Sample records for microsc res tech

  1. The effects of acid erosion and remineralization on enamel and three different dental materials: FT-Raman spectroscopy and scanning electron microscopy analysis.

    PubMed

    Soares, Luís Eduardo Silva; Soares, Ana Lúcia Silva; De Oliveira, Rodrigo; Nahórny, Sidnei

    2016-07-01

    FT-Raman spectroscopy and scanning electron microscopy (SEM) were employed to test the hypothesis that the beverage consumption or mouthwash utilization would change the chemistry of dental materials and enamel inorganic content. Bovine enamel samples (n = 36) each received two cavity preparations (n = 72), each pair filled with one of three dental materials (R: nanofilled composite resin, GIC: glass-ionomer cement, RMGIC: resin-modified GIC). Furthermore, they were treated with three different solutions (S: artificial saliva, E: erosion/Pepsi Twist or EM: erosion + mouthwash/Colgate Plax). Reduction of carbonate content of enamel was greater in RE than RS (P < 0.01). Increment of carbonate was greater in GICEM than in GICE and GICS (P < 0.01; P < 0.001). Significant material degradation was found in RE, REM, GICE, and GICEM than in RS and GICS (P < 0.01; P < 0.001). SEM showed clear enamel demineralization after erosion. Material degradation was greater after E and EM than S. GIC and RMGIC materials had a positive effect against acid erosion in the adjacent enamel after remineralization with mouthwash. The beverage and mouthwash utilization would change R and GIC chemical properties. A professional should periodically monitor the glass-ionomer and resin restorations, as they degrade over time under erosive challenges and mouthwash utilization. Microsc. Res. Tech., 2016. © 2016 Wiley Periodicals, Inc. Microsc. Res. Tech. 79:646-656, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  2. Micromorphological characterization of zinc/silver particle composite coatings

    PubMed Central

    Méndez, Alia; Reyes, Yolanda; Trejo, Gabriel; StĘpień, Krzysztof

    2015-01-01

    ABSTRACT The aim of this study was to evaluate the three‐dimensional (3D) surface micromorphology of zinc/silver particles (Zn/AgPs) composite coatings with antibacterial activity prepared using an electrodeposition technique. These 3D nanostructures were investigated over square areas of 5 μm × 5 μm by atomic force microscopy (AFM), fractal, and wavelet analysis. The fractal analysis of 3D surface roughness revealed that (Zn/AgPs) composite coatings have fractal geometry. Triangulation method, based on the linear interpolation type, applied for AFM data was employed in order to characterise the surfaces topographically (in amplitude, spatial distribution and pattern of surface characteristics). The surface fractal dimension D f, as well as height values distribution have been determined for the 3D nanostructure surfaces. Microsc. Res. Tech. 78:1082–1089, 2015. © 2015 The Authors published by Wiley Periodicals, Inc. PMID:26500164

  3. Microstructure and mechanical properties of sheep horn.

    PubMed

    Zhu, Bing; Zhang, Ming; Zhao, Jian

    2016-07-01

    The sheep horn presents outstanding mechanical properties of impact resistance and energy absorption, which suits the need of the vehicle bumper design, but the mechanism behind this phenomenon is less investigated. The microstructure and mechanical properties of the sheep horn of Small Tailed Han Sheep (Ovis aries) living in northeast China were investigated in this article. The effect of sampling position and orientation of the sheep horn sheath on mechanical properties were researched by tensile and compression tests. Meanwhile, the surface morphology and microstructure of the sheep horn were observed using scanning electron microscopy (SEM). The formation mechanism of the mechanical properties of the sheep horn was investigated by biological coupling analysis. The analytical results indicated that the outstanding mechanical properties of the sheep horn are determined by configuration, structure, surface morphology and material coupling elements. These biological coupling elements make the sheep horn possess super characteristics of crashworthiness and energy absorption through the internal coupling mechanism. We suppose that these findings would make a difference in vehicle bumper design. Microsc. Res. Tech. 79:664-674, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  4. A beginner's guide to atomic force microscopy probing for cell mechanics

    PubMed Central

    2016-01-01

    Abstract Atomic Force microscopy (AFM) is becoming a prevalent tool in cell biology and biomedical studies, especially those focusing on the mechanical properties of cells and tissues. The newest generation of bio‐AFMs combine ease of use and seamless integration with live‐cell epifluorescence or more advanced optical microscopies. As a unique feature with respect to other bionanotools, AFM provides nanometer‐resolution maps for cell topography, stiffness, viscoelasticity, and adhesion, often overlaid with matching optical images of the probed cells. This review is intended for those about to embark in the use of bio‐AFMs, and aims to assist them in designing an experiment to measure the mechanical properties of adherent cells. In addition to describing the main steps in a typical cell mechanics protocol and explaining how data is analysed, this review will also discuss some of the relevant contact mechanics models available and how they have been used to characterize specific features of cellular and biological samples. Microsc. Res. Tech. 80:75–84, 2017. © 2016 Wiley Periodicals, Inc. PMID:27676584

  5. Laser-induced reversion of δ' precipitates in an Al-Li alloy: Study on temperature rise in pulsed laser atom probe.

    PubMed

    Khushaim, Muna; Gemma, Ryota; Al-Kassab, Talaat

    2016-08-01

    The influence of tuning the laser pulse energy during the analyses on the resulting microstructure in a specimen utilizing an ultra-fast laser assisted atom probe was demonstrated by a case study of a binary Al-Li alloy. The decomposition parameters, such as the size, number density, volume fraction, and composition of δ' precipitates, were carefully monitored after each analysis. A simple model was employed to estimate the corresponding specimen temperature for each value of the laser energy. The results indicated that the corresponding temperatures for the laser pulse energy in the range of 10 to 80 pJ are located inside the miscibility gap of the binary Al-Li phase diagram and fall into the metastable equilibrium field. In addition, the corresponding temperature for a laser pulse energy of 100 pJ was in fairly good agreement with reported range of  δ' solvus temperature, suggesting a result of reversion upon heating due to laser pulsing. Microsc. Res. Tech. 79:727-737, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  6. The external morphology of adult female Egrasilus labracis as shown using hexamethyldisilazane treated, uncoated specimens for scanning electron microscopy.

    PubMed

    Murray, Harry M; Hill, Stephen J; Ang, Keng P

    2016-07-01

    The description and application of a modified Scanning Electron Microscope preparation technique using hexamethyldisilazane for small parasitic copepods was demonstrated though a high resolution depiction of individuals of Ergasilus labracis sampled from three spined stickleback (Gasterosteus aculeatus) in Bay D'Espoir, Newfoundland during summer 2015 and from archival samples retrieved from Atlantic salmon par (Salmo salar) stored at the Atlantic reference centre, St. Andrews, New Brunswick. The specimens were very well preserved showing high quality detail of important features and verifying those previously described using light microscopy by Hogans. Additionally the technique allowed excellent in situ demonstrations of mouth parts, swimming legs, and unusual and previously undescribed features of the second antenna including prominent striations and pore-like structures found to define the claw. It is thought that this technique will become a quick and efficient tool for describing important taxonomic features of small parasitic copepods like E. labracis or other similar small aquatic organisms. Microsc. Res. Tech. 79:657-663, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  7. Albumin microvascular leakage in brains with diabetes mellitus.

    PubMed

    Fujihara, Ryuji; Chiba, Yoichi; Nakagawa, Toshitaka; Nishi, Nozomu; Murakami, Ryuta; Matsumoto, Koichi; Kawauchi, Machi; Yamamoto, Tetsuji; Ueno, Masaki

    2016-09-01

    Their aim was to examine whether microvascular leakage of endogenous albumin, a representative marker for blood-brain barrier (BBB) damage, was induced in the periventricular area of diabetic db/db mice because periventricular white matter hyperintensity formation in magnetic resonance images was accelerating in elderly patients with diabetes mellitus. Using light and electron microscopes, and semi-quantitative analysis techniques, immunoreactivity of endogenous albumin, indicating vascular permeability, was examined in the periventricular area and spinal cord of db/db mice and db/+m control mice. Greater immunoreactivity of albumin was observed in the vessel wall of the periventricular area of db/db mice than in controls. Additionally, weak immunoreactivity was observed in the spinal cord of both db/db mice and controls. The number of gold particles, indicating immunoreactivity of albumin, in the perivascular area of db/db mice was significantly higher than that of control mice, but there was no significant difference in the number of particles in the spinal cord between db/db mice and controls. These findings suggest that albumin microvascular leakage, or BBB breakdown, is induced in the periventricular area of diabetic mice. Microsc. Res. Tech. 79:833-837, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  8. Semiautomated confocal imaging of fungal pathogenesis on plants: Microscopic analysis of macroscopic specimens.

    PubMed

    Minker, Katharine R; Biedrzycki, Meredith L; Kolagunda, Abhishek; Rhein, Stephen; Perina, Fabiano J; Jacobs, Samuel S; Moore, Michael; Jamann, Tiffany M; Yang, Qin; Nelson, Rebecca; Balint-Kurti, Peter; Kambhamettu, Chandra; Wisser, Randall J; Caplan, Jeffrey L

    2018-02-01

    The study of phenotypic variation in plant pathogenesis provides fundamental information about the nature of disease resistance. Cellular mechanisms that alter pathogenesis can be elucidated with confocal microscopy; however, systematic phenotyping platforms-from sample processing to image analysis-to investigate this do not exist. We have developed a platform for 3D phenotyping of cellular features underlying variation in disease development by fluorescence-specific resolution of host and pathogen interactions across time (4D). A confocal microscopy phenotyping platform compatible with different maize-fungal pathosystems (fungi: Setosphaeria turcica, Cochliobolus heterostrophus, and Cercospora zeae-maydis) was developed. Protocols and techniques were standardized for sample fixation, optical clearing, species-specific combinatorial fluorescence staining, multisample imaging, and image processing for investigation at the macroscale. The sample preparation methods presented here overcome challenges to fluorescence imaging such as specimen thickness and topography as well as physiological characteristics of the samples such as tissue autofluorescence and presence of cuticle. The resulting imaging techniques provide interesting qualitative and quantitative information not possible with conventional light or electron 2D imaging. Microsc. Res. Tech., 81:141-152, 2018. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  9. Biotinylated vanadium and chromium sulfide nanoparticles as probes for colocalization of membrane proteins.

    PubMed

    Loukanov, Alexandre; Emin, Saim

    2016-09-01

    We report the microemulsion synthesis of vanadium and chromium sulfide nanoparticles (NPs) and their biological application as nanoprobes for colocalization of membrane proteins. Spherical V2 S3 and Cr2 S3 NPs were prepared in reverse microemulsion droplets, as nanoreactors, obtained by the surfactant sodium bis(2-ethylhexyl) sulfosuccinate (AOT) in nonpolar organic phase (heptane). Electron microscopic data indicated that the size distribution of the nanoparticles was uniform with an average diameter between 3 ÷ 5 nm. The prepared hydrophobic nanocrystals were transferred in aqueous phase by surface cap exchange of AOT with biotin-dihydrolipoic ligands. This substitution allows the nanoparticles solubility in aqueous solutions and confer their bioactivity. In addition, we report the conjugation procedure between α-Lipoic acid (LA) and biotin (abbreviated as biotin-LA). The biotin-LA structure was characterized by 1D and 2D NMR spectroscopy. The biotinylated vanadium and chromium sulfide nanoparticles were tested as probes for colocalization of glutamate receptors on sodium-dodecyl-sulfate-digested replica prepared from rat hippocampus. The method suggests their high labeling efficiency for study of membrane biological macromolecules. Microsc. Res. Tech. 79:799-805, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  10. The cutting of ultrathin sections with the thickness less than 20 nm from biological specimens embedded in resin blocks.

    PubMed

    Nebesářová, Jana; Hozák, Pavel; Frank, Luděk; Štěpan, Petr; Vancová, Marie

    2016-06-01

    Low voltage electron microscopes working in transmission mode, like LVEM5 (Delong Instruments, Czech Republic) working at accelerating voltage 5 kV or scanning electron microscope working in transmission mode with accelerating voltage below 1 kV, require ultrathin sections with the thickness below 20 nm. Decreasing of the primary electron energy leads to enhancement of image contrast, which is especially useful in the case of biological samples composed of elements with low atomic numbers. As a result treatments with heavy metals, like post-fixation with osmium tetroxide or ultrathin section staining, can by omitted. The disadvantage is reduced penetration ability of incident electrons influencing the usable thickness of the specimen resulting in the need of ultrathin sections of under 20 nm thickness. In this study we want to answer basic questions concerning the cutting of extremely ultrathin sections: Is it possible routinely and reproducibly to cut extremely thin sections of biological specimens embedded in commonly used resins with contemporary ultramicrotome techniques and under what conditions? Microsc. Res. Tech. 79:512-517, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. Advanced light microscopy core facilities: Balancing service, science and career

    PubMed Central

    Hartmann, Hella; Reymann, Jürgen; Ansari, Nariman; Utz, Nadine; Fried, Hans‐Ulrich; Kukat, Christian; Peychl, Jan; Liebig, Christian; Terjung, Stefan; Laketa, Vibor; Sporbert, Anje; Weidtkamp‐Peters, Stefanie; Schauss, Astrid; Zuschratter, Werner; Avilov, Sergiy

    2016-01-01

    ABSTRACT Core Facilities (CF) for advanced light microscopy (ALM) have become indispensable support units for research in the life sciences. Their organizational structure and technical characteristics are quite diverse, although the tasks they pursue and the services they offer are similar. Therefore, throughout Europe, scientists from ALM‐CFs are forming networks to promote interactions and discuss best practice models. Here, we present recommendations for ALM‐CF operations elaborated by the workgroups of the German network of ALM‐CFs, German Bio‐Imaging (GerBI). We address technical aspects of CF planning and instrument maintainance, give advice on the organization and management of an ALM‐CF, propose a scheme for the training of CF users, and provide an overview of current resources for image processing and analysis. Further, we elaborate on the new challenges and opportunities for professional development and careers created by CFs. While some information specifically refers to the German academic system, most of the content of this article is of general interest for CFs in the life sciences. Microsc. Res. Tech. 79:463–479, 2016. © 2016 THE AUTHORS MICROSCOPY RESEARCH AND TECHNIQUE PUBLISHED BY WILEY PERIODICALS, INC. PMID:27040755

  12. Advanced light microscopy core facilities: Balancing service, science and career.

    PubMed

    Ferrando-May, Elisa; Hartmann, Hella; Reymann, Jürgen; Ansari, Nariman; Utz, Nadine; Fried, Hans-Ulrich; Kukat, Christian; Peychl, Jan; Liebig, Christian; Terjung, Stefan; Laketa, Vibor; Sporbert, Anje; Weidtkamp-Peters, Stefanie; Schauss, Astrid; Zuschratter, Werner; Avilov, Sergiy

    2016-06-01

    Core Facilities (CF) for advanced light microscopy (ALM) have become indispensable support units for research in the life sciences. Their organizational structure and technical characteristics are quite diverse, although the tasks they pursue and the services they offer are similar. Therefore, throughout Europe, scientists from ALM-CFs are forming networks to promote interactions and discuss best practice models. Here, we present recommendations for ALM-CF operations elaborated by the workgroups of the German network of ALM-CFs, German Bio-Imaging (GerBI). We address technical aspects of CF planning and instrument maintainance, give advice on the organization and management of an ALM-CF, propose a scheme for the training of CF users, and provide an overview of current resources for image processing and analysis. Further, we elaborate on the new challenges and opportunities for professional development and careers created by CFs. While some information specifically refers to the German academic system, most of the content of this article is of general interest for CFs in the life sciences. Microsc. Res. Tech. 79:463-479, 2016. © 2016 THE AUTHORS MICROSCOPY RESEARCH AND TECHNIQUE PUBLISHED BY WILEY PERIODICALS, INC. © 2016 The Authors Microscopy Research and Technique Published by Wiley Periodicals, Inc.

  13. Tip in–light on: Advantages, challenges, and applications of combining AFM and Raman microscopy on biological samples

    PubMed Central

    Gierlinger, Notburga

    2016-01-01

    Abstract Scanning probe microscopies and spectroscopies, especially AFM and Confocal Raman microscopy are powerful tools to characterize biological materials. They are both non‐destructive methods and reveal mechanical and chemical properties on the micro and nano‐scale. In the last years the interest for increasing the lateral resolution of optical and spectral images has driven the development of new technologies that overcome the diffraction limit of light. The combination of AFM and Raman reaches resolutions of about 50–150 nm in near‐field Raman and 1.7–50 nm in tip enhanced Raman spectroscopy (TERS) and both give a molecular information of the sample and the topography of the scanned surface. In this review, the mentioned approaches are introduced, the main advantages and problems for application on biological samples discussed and some examples for successful experiments given. Finally the potential of colocated AFM and Raman measurements is shown on a case study of cellulose‐lignin films: the topography structures revealed by AFM can be related to a certain chemistry by the colocated Raman scan and additionally the mechanical properties be revealed by using the digital pulsed force mode. Microsc. Res. Tech. 80:30–40, 2017. © 2016 Wiley Periodicals, Inc. PMID:27514318

  14. Ambient atomic resolution atomic force microscopy with qPlus sensors: Part 1.

    PubMed

    Wastl, Daniel S

    2017-01-01

    Atomic force microscopy (AFM) is an enormous tool to observe nature in highest resolution and understand fundamental processes like friction and tribology on the nanoscale. Atomic resolution in highest quality was possible only in well-controlled environments like ultrahigh vacuum (UHV) or controlled buffer environments (liquid conditions) and more specified for long-term high-resolution analysis at low temperatures (∼4 K) in UHV where drift is nearly completely absent. Atomic resolution in these environments is possible and is widely used. However, in uncontrolled environments like air, with all its pollutants and aerosols, unspecified thin liquid films as thin as a single molecular water-layer of 200 pm or thicker condensation films with thicknesses up to hundred nanometer, have been a problem for highest resolution since the invention of the AFM. The goal of true atomic resolution on hydrophilic as well as hydrophobic samples was reached recently. In this manuscript we want to review the concept of ambient AFM with atomic resolution. The reader will be introduced to the phenomenology in ambient conditions and the problems will be explained and analyzed while a method for scan parameter optimization will be explained. Recently developed concepts and techniques how to reach atomic resolution in air and ultra-thin liquid films will be shown and explained in detail, using several examples. Microsc. Res. Tech. 80:50-65, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  15. Live imaging of fluorescent proteins in chordate embryos: from ascidians to mice.

    PubMed

    Passamaneck, Yale J; Di Gregorio, Anna; Papaioannou, Virginia E; Hadjantonakis, Anna-Katerina

    2006-03-01

    Although we have advanced in our understanding of the molecular mechanisms intrinsic to the morphogenesis of chordate embryos, the question of how individual developmental events are integrated to generate the final morphological form is still unresolved. Microscopic observation is a pivotal tool in developmental biology, both for determining the normal course of events and for contrasting this with the results of experimental and pathological perturbations. Since embryonic development takes place in three dimensions over time, to fully understand the events required to build an embryo we must investigate embryo morphogenesis in multiple dimensions in situ. Recent advances in the isolation of naturally fluorescent proteins, and the refinement of techniques for in vivo microscopy offer unprecedented opportunities to study the cellular and molecular events within living, intact embryos using optical imaging. These technologies allow direct visual access to complex events as they happen in their native environment, and thus provide greater insights into cell behaviors operating during embryonic development. Since most fluorescent protein probes and modes of data acquisition are common across species, we have chosen the mouse and the ascidian, two model organisms at opposite ends of the chordate clade, to review the use of some of the current genetically-encoded fluorescent proteins and their visualization in vivo in living embryos for the generation of high-resolution imaging data. Microsc. Res. Tech. 69:160-167, 2006. (c) 2006 Wiley-Liss, Inc.

  16. Advanced imaging of tau pathology in Alzheimer Disease: New perspectives from super resolution microscopy and label-free nanoscopy.

    PubMed

    Schierle, Gabriele S Kaminski; Michel, Claire H; Gasparini, Laura

    2016-08-01

    Alzheimer's disease (AD) is the main cause of dementia in the elderly population. Over 30 million people worldwide are living with dementia and AD prevalence is projected to increase dramatically in the next two decades. In terms of neuropathology, AD is characterized by two major cerebral hallmarks: extracellular β-amyloid (Aβ) plaques and intracellular Tau inclusions, which start accumulating in the brain 15-20 years before the onset of symptoms. Within this context, the scientific community worldwide is undertaking a wide research effort to detect AD pathology at its earliest, before symptoms appear. Neuroimaging of Aβ by positron emission tomography (PET) is clinically available and is a promising modality for early detection of Aβ pathology and AD diagnosis. Substantive efforts are ongoing to develop advanced imaging techniques for early detection of Tau pathology. Here, we will briefly describe the key features of Tau pathology and its heterogeneity across various neurodegenerative diseases bearing cerebral Tau inclusions (i.e., tauopathies). We will outline the current status of research on Tau-specific PET tracers and their clinical development. Finally, we will discuss the potential application of novel super-resolution and label-free techniques for investigating Tau pathology at the experimental level and their potential application for AD diagnosis. Microsc. Res. Tech. 79:677-683, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  17. Investigating cell-substrate and cell-cell interactions by means of single-cell-probe force spectroscopy.

    PubMed

    Moreno-Cencerrado, Alberto; Iturri, Jagoba; Pecorari, Ilaria; D M Vivanco, Maria; Sbaizero, Orfeo; Toca-Herrera, José L

    2017-01-01

    Cell adhesion forces are typically a mixture of specific and nonspecific cell-substrate and cell-cell interactions. In order to resolve these phenomena, Atomic Force Microscopy appears as a powerful device which can measure cell parameters by means of manipulation of single cells. This method, commonly known as cell-probe force spectroscopy, allows us to control the force applied, the area of interest, the approach/retracting speed, the force rate, and the time of interaction. Here, we developed a novel approach for in situ cantilever cell capturing and measurement of specific cell interactions. In particular, we present a new setup consisting of two different half-surfaces coated either with recrystallized SbpA bacterial cell surface layer proteins (S-layers) or integrin binding Fibronectin, on which MCF-7 breast cancer cells are incubated. The presence of a clear physical boundary between both surfaces benefits for a quick detection of the region under analysis. Thus, quantitative results about SbpA-cell and Fibronectin-cell adhesion forces as a function of the contact time are described. Additionally, the importance of the cell spreading in cell-cell interactions has been studied for surfaces coated with two different Fibronectin concentrations: 20 μg/mL (FN20) and 100 μg/mL (FN100), which impact the number of substrate receptors. Microsc. Res. Tech. 80:124-130, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  18. Spectral characterization of Dictyostelium autofluorescence.

    PubMed

    Engel, Ruchira; Van Haastert, Peter J M; Visser, Antonie J W G

    2006-03-01

    Dictyostelium discoideum is used extensively as a model organism for the study of chemotaxis. In recent years, an increasing number of studies of Dictyostelium chemotaxis have made use of fluorescence-based techniques. One of the major factors that can interfere with the application of these techniques in cells is the cellular autofluorescence. In this study, the spectral properties of Dictyostelium autofluorescence have been characterized using fluorescence microscopy. Whole cell autofluorescence spectra obtained using spectral imaging microscopy show that Dictyostelium autofluorescence covers a wavelength range from approximately 500 to 650 nm with a maximum at approximately 510 nm, and thus, potentially interferes with measurements of green fluorescent protein (GFP) fusion proteins with fluorescence microscopy techniques. Further characterization of the spatial distribution, intensity, and brightness of the autofluorescence was performed with fluorescence confocal microscopy and fluorescence fluctuation spectroscopy (FFS). The autofluorescence in both chemotaxing and nonchemotaxing cells is localized in discrete areas. The high intensity seen in cells incubated in the growth medium HG5 reduces by around 50% when incubated in buffer, and can be further reduced by around 85% by photobleaching cells for 5-7 s. The average intensity and spatial distribution of the autofluorescence do not change with long incubations in the buffer. The cellular autofluorescence has a seven times lower molecular brightness than eGFP. The influence of autofluorescence in FFS measurements can be minimized by incubating cells in buffer during the measurements, pre-bleaching, and making use of low excitation intensities. The results obtained in this study thus offer guidelines to the design of future fluorescence studies of Dictyostelium. Microsc. Res. Tech. 69:168-174, 2006. (c) 2006 Wiley-Liss, Inc.

  19. Increase of forage dryness induces differentiated anatomical response in the sheep rumen compartments.

    PubMed

    Scocco, Paola; Mercati, Francesca; Tardella, Federico Maria; Catorci, Andrea

    2016-08-01

    The aim of this study was to investigate how the Surface Enlargement Factor (SEF) and the epithelial keratinization degree of sheep rumen change in response to phytomass production, and to forage fiber and water content during the pasture vegetative cycle. The study used eighteen sheep nourished with dry hay and cereals during the winter season and with fresh hay during the pasture vegetative cycle. We collected samples from rumen indicative regions for two consecutive years characterized by different rainfall and pasture productivity values. We evaluated the densities (D) of rumen papillae to estimate the rumen SEF, and the keratinization percentage of the epithelial lining; these parameters showed differentiated modifications in the four ruminal analyzed compartments in response to pasture seasonal conditions. In addition, we performed Canonical Redundancy Analysis (RDA) on the "keratinization and SEF" matrix constrained by phytomass, water, and crude fiber contents of pasture at different time in the two considered years to highlight how rumen features answer to pasture conditions. Atrium (A) and ventral sac (VS) keratinization showed a strict positive correlation to crude fiber, while SEF of VS was positively related to phytomass and forage water content. The degree of keratinization of the rumen VS epithelium proved to be a useful parameter for evaluating anatomical variations in the short term period related to pasture features; in addition, its monitoring could be carried out through biopsy, thus avoiding the killing of animals. The study also leads to the application of the 3Rs (Replacement; Reduction; and Refinement). Microsc. Res. Tech. 79:738-743, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  20. Cytotoxic effects of extract of Acmella oleraceae (Jambú) in Rhipicephalus microplus females ticks.

    PubMed

    de Oliveira, Patrícia Rosa; de Carvalho Castro, Karina Neoob; Anholeto, Luis Adriano; Camargo Mathias, Maria Izabel

    2016-08-01

    The present study analyzed the effects of different concentrations of the hexane extract of A. oleraceae (HEAO) (Jambú) on the germ cells of semi-engorged Rhipicephalus microplus female ticks, through a morpho-histological study, evaluating the effectiveness of the extract in the genesis of the individuals. To perform this analysis, 100 semi-engorged females were divided into five groups with 20 individuals each: groups I and II, respectively constituted by distilled water control and 50% ethanol + 1% DMSO, and groups III, IV, and V constituted by treatment with HEAO in the concentrations of 12.5, 25.0 and 50.0 mg/mL, respectively. All the ticks were immersed in the different concentrations of the extract or in distilled water for 5 minutes, dried and conditioned in BOD incubator for 7 days. The individuals of the treatment groups revealed the action of this extract showing alterations in the germ cells of the females from the different groups when compared with those from the groups I and II (control groups). These alterations were mainly related to the size and shape of the oocytes; number of yolk granules; presence, number, size and location of vacuoles in the cytoplasm of all the germ cells; and the presence of nuclear alterations in these cells as well. Thus, it was demonstrated that the concentrations of HEAO affected the germ cells of R. microplus ticks. The effects of the extract are similar to those caused by renowned and efficient chemical products used to control these ticks. Microsc. Res. Tech. 79:744-753, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  1. Iodine Vapor Staining for Atomic Number Contrast in Backscattered Electron and X-ray Imaging

    PubMed Central

    Boyde, Alan; Mccorkell, Fergus A; Taylor, Graham K; Bomphrey, Richard J; Doube, Michael

    2014-01-01

    Iodine imparts strong contrast to objects imaged with electrons and X-rays due to its high atomic number (53), and is widely used in liquid form as a microscopic stain and clinical contrast agent. We have developed a simple technique which exploits elemental iodine's sublimation-deposition state-change equilibrium to vapor stain specimens with iodine gas. Specimens are enclosed in a gas-tight container along with a small mass of solid I2. The bottle is left at ambient laboratory conditions while staining proceeds until empirically determined completion (typically days to weeks). We demonstrate the utility of iodine vapor staining by applying it to resin-embedded tissue blocks and whole locusts and imaging them with backscattered electron scanning electron microscopy (BSE SEM) or X-ray microtomography (XMT). Contrast is comparable to that achieved with liquid staining but without the consequent tissue shrinkage, stain pooling, or uneven coverage artefacts associated with immersing the specimen in iodine solutions. Unmineralized tissue histology can be read in BSE SEM images with good discrimination between tissue components. Organs within the locust head are readily distinguished in XMT images with particularly useful contrast in the chitin exoskeleton, muscle and nerves. Here, we have used iodine vapor staining for two imaging modalities in frequent use in our laboratories and on the specimen types with which we work. It is likely to be equally convenient for a wide range of specimens, and for other modalities which generate contrast from electron- and photon-sample interactions, such as transmission electron microscopy and light microscopy. Microsc. Res. Tech. 77:1044–1051, 2014. © 2014 The Authors. Microscopy Research Technique published by Wiley Periodocals, Inc. PMID:25219801

  2. Seasonal changes in hepatocytic lipid droplets, glycogen deposits, and rough endoplasmic reticulum along the natural breeding cycle of female ohrid trout (Salmo letnica Kar.)-A semiquantitative ultrastructural study.

    PubMed

    Jordanova, Maja; Rebok, Katerina; Malhão, Fernanda; Rocha, Maria J; Rocha, Eduardo

    2016-08-01

    This study on wild female Ohrid trout was primarily designed to provide a general overview of the breeding cycle influence upon selected aspects of hepatocytes. According with a semiquantitatively evaluation, some of these cell's structural compartments change during the breeding cycle. Structural modifications were disclosed in the relative occurrence of lipid, glycogen, and RER content during breeding cycle. The relative amount of lipid deposits in the hepatocytes was much greater in previtellogenesis, and decreased postspawning. So, while the seasonal changes in RER were positively related with the ovary maturation status, those of the lipid droplets followed an opposite trend. The hepatocytic glycogen occurred rarely, mainly in late-vitellogenesis and spawning, suggesting that in this species such kind of energy storage is comparatively unimportant. Lipid accumulation and later usage is, probably, the relevant biochemical pathway for Ohrid trout in the wild. While glycogen and RER contents were positively correlated with the gonadosomatic index, lipids were negatively correlated. Additionally, glycogen inclusions were positively correlated with the plasma estradiol levels. When comparing seasonal patterns from wild Ohrid trout with those from well-studied rainbow and brown trout (specimens studied were from aquaculture), there are contradicting results as to lipid and glycogen reserves, and also as to RER loads. The differences among the mentioned trout can result from intrinsic interspecies differences or may be associated with natural feeding conditions versus feeding with commercially prepared diets, or other factors. This study offers new data useful as standard to access liver pathology in wild and aquacultured Ohrid trout. Microsc. Res. Tech. 79:700-706, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. MOBILE EMISSIONS ASSESSMENT SYSTEM FOR URBAN AND REGIONAL EVALUATION

    EPA Science Inventory

    A working research model for Atlanta, GA has been developed by Georgia Tech, and is called the Mobile Emissions Assessment System for Urban and Regional Evaluation (MEASURE). The EPA Office of Research and Development has developed an additional implementation of the MEASURE res...

  4. Leidos Biomed Teams with NCI, DOE, and Argonne National Lab to Support National X-Ray Resource | FNLCR Staging

    Cancer.gov

    Scientists are making progress in understanding a bleeding disorder caused by prescription drug interactions, thanks to a high-tech research facility involving two federal national laboratories, Argonne and Frederick. Miroslawa Dauter is a Senior Res

  5. Metabolic Mapping of Breast Cancer with Multiphoton Spectral and Lifetime Imaging

    DTIC Science & Technology

    2008-03-01

    Biomedical Optics May/June 2008 Vol. 133031220-1 the most prevalent cancer among women . 1 Therefore, tech- nologies to detect, classify, study, and...and molecular function using optical imaging: applications to breast cancer,” Breast Cancer Res. Treat. 31, 41–46 2001. 3. M. Sidani , J. Wyckoff

  6. FE-ANN based modeling of 3D Simple Reinforced Concrete Girders for Objective Structural Health Evaluation : Tech Transfer Summary

    DOT National Transportation Integrated Search

    2017-06-01

    The objective of this study was to develop an objective, quantitative method for evaluating damage to bridge girders by using artificial neural networks (ANNs). This evaluation method, which is a supplement to visual inspection, requires only the res...

  7. Studies of Heat Transfer in Complex Internal Flows.

    DTIC Science & Technology

    1982-01-01

    D.C. 20362 (Tel 202-692-6874) Mr. Richard S. Carlton Director, Engines Division, Code 523 NC #4 Naval Sea Systems Command Washington, D.C. 20362...Walter Ritz Code 033C Naval Ships Systems Engineering Station Philadelphia, Pennsylvania 19112 (Tel. 215-755-3841) Dr. Simion Kuo United Tech. Res

  8. Transport of Nordic Seas Overflow Water into and Within the Irminger Sea: An Eddy-Resolving Simulation and Observations

    DTIC Science & Technology

    2010-12-18

    grated for 20 years after initialization from rest and January temperature (T) and salinity (S) from the Generalized Digital Environmental Model ( GDEM ...coordinates, Ocean Modell., 37, 55–88. Carnes, M. R. (2009), Description and evaluation of GDEM ‐V 3.0, Tech. Rep. 724/NRL/MR/7300‐09‐9165, Nav. Res. Lab

  9. Investigating the tool marks on oracle bones inscriptions from the Yinxu site (ca., 1319-1046 BC), Henan province, China.

    PubMed

    Zhao, Xiaolong; Tang, Jigen; Gu, Zhou; Shi, Jilong; Yang, Yimin; Wang, Changsui

    2016-09-01

    Oracle Bone Inscriptions in the Shang dynasty (1600-1046 BC) are the earliest well-developed writing forms of the Chinese character system, and their carving techniques have not been studied by tool marks analysis with microscopy. In this study, a digital microscope with three-dimensional surface reconstruction based on extended depth of focus technology was used to investigate tool marks on the surface of four pieces of oracle bones excavated at the eastern area of Huayuanzhuang, Yinxu site(ca., 1319-1046 BC), the last capital of the Shang dynasty, Henan province, China. The results show that there were two procedures to carve the characters on the analyzed tortoise shells. The first procedure was direct carving. The second was "outlining design," which means to engrave a formal character after engraving a draft with a pointed tool. Most of the strokes developed by an engraver do not overlap the smaller draft, which implies that the outlining design would be a sound way to avoid errors such as wrong and missing characters. The strokes of these characters have different shape at two ends and variations on width and depth of the grooves. Moreover, the bottom of the grooves is always rugged. Thus, the use of rotary wheel-cutting tools could be ruled out. In most cases, the starting points of the strokes are round or flat while the finishing points are always pointed. Moreover, the strokes should be engraved from top to bottom. When vertical or horizontal strokes had been engraved, the shell would be turned about 90 degrees to engrave the crossed strokes from top to bottom. There was no preferred order to engrave vertical or horizontal strokes. Since both sides of the grooves of the characters are neat and there exists no unorganized tool marks, then it is suggested that some sharp tools had been used for engraving characters on the shells. Microsc. Res. Tech. 79:827-832, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  10. Proceedings of the Annual Military Librarians’ Workshop (28th): Cost of Library Operations 1984 and Beyond Held at Panama City Beach, Florida on 17-19 October 1984

    DTIC Science & Technology

    1985-10-01

    Aviation Tech Lib Ft. Rucker, AL Dave Hlanna Naval Underwater Sys Ctr New London, CT Barbara Witt Defence Res Est, Pac Victoria, BC CONTENTS PAGE...solved problems, and is the key to eventually build- -,r s’s-• -"a• gch can reasoti across knowledge areas; and common sense reason- an•jn v:- nabe the

  11. Physical, Nutrient, and Biological Measurements of Coastal Waters off Central California in March 2012

    DTIC Science & Technology

    2012-10-01

    Salinity Scale, 1978 ( UNESCO , 1981). Dissolved oxygen (Winkler) samples were collected at CTD stations 2, 6, 10, 16, 17, and 19. These were...the Farallones. Deep-Sea Res. II 47: 907- 946. UNESCO . Background papers and supporting data on the Practical Salinity Scale, 1978. 1981... UNESCO Tech. Pap. In: Mar. Sci. 37. Venrick, E. L., and T. L. Hayward. 1984. Determining chlorophyll on the 1984 CalCOFI surveys. CalCOFI Rep

  12. Apparatus and method for the electrolysis of water

    DOEpatents

    Greenbaum, Elias

    2015-04-21

    An apparatus for the electrolytic splitting of water into hydrogen and/or oxygen, the apparatus comprising: (i) at least one lithographically-patternable substrate having a surface; (ii) a plurality of microscaled catalytic electrodes embedded in said surface; (iii) at least one counter electrode in proximity to but not on said surface; (iv) means for collecting evolved hydrogen and/or oxygen gas; (v) electrical powering means for applying a voltage across said plurality of microscaled catalytic electrodes and said at least one counter electrode; and (vi) a container for holding an aqueous electrolyte and housing said plurality of microscaled catalytic electrodes and said at least one counter electrode. Electrolytic processes using the above electrolytic apparatus or functional mimics thereof are also described.

  13. Crystal Field Splittings of the Hund Ground States of Nd(N) Ions in S4 Symmetry: Theory and Application to the Ga(3+) Site of Gd3Sc2Ga3O12.

    DTIC Science & Technology

    1984-03-01

    DRDAR-TSS-S (STINFO) ATTN DRXRES-RTL, TECH LIBRARY ABERDEN PROVING GROUND , MD 21005 NATICK, MA 01762 23 %.. * ,w...DRXSY-MP (LIBRARY) ABERDEEN PROVING GROUND , MD 21005 UNDER SECRETARY OF DEFENSE RES £ ENGINEERING COMMANDER ATTN TECHNICAL LIBRARY, 3C128 US ARMY MISSILE...SANDS MISSILE RANGE, N 88002 ABERDEEN PROVING GROUND , MD 21005 DIRECTOR COMMANDER 08 RMM BALLISTIC RESEARCH LABORATORY US ARMY TROOP SUPPORT COMMAND AT

  14. Mean Atlantic Meridional Overturning Circulation Across 26.5 degs N from Eddy-Resolving Simulations Compared to Observations

    DTIC Science & Technology

    2012-03-30

    climatology, the Gen- eralized Digital Environmental Model ( GDEM [Carnes, 2009]), with an e-folding time of 5–60 days that increases with distance from the...after 10 years of integration due to an oversight. As a third change, E026 uses a new version of GDEM for initialization and buffer zone restor- ing...Carnes, M. R. (2009), Description and evaluation of GDEM -V3.0, Tech. Rep. NRL/ MR/7330–09-9165, 21 pp., Naval Res. Lab., Stennis Space Cent., Miss

  15. Analysis of renewable energy projects' implementation in Russia

    NASA Astrophysics Data System (ADS)

    Ratner, S. V.; Nizhegorodtsev, R. M.

    2017-06-01

    With the enactment in 2013 of a renewable energy scheme by contracting qualified power generation facilities working on renewable energy sources (RES), the process of construction and connection of such facilities to the Federal Grid Company has intensified in Russia. In 2013-2015, 93 projects of solar, wind, and small hydropower energy were selected on the basis of competitive bidding in the country with the purpose of subsequent support. Despite some technical and organizational problems and a time delay of some RES projects, in 2014-2015 five solar generating facilities with total capacity of 50 MW were commissioned, including 30 MW in Orenburg oblast. However, the proportion of successful projects is low and amounts to approximately 30% of the total number of announced projects. The purpose of this paper is to analyze the experience of implementation of renewable energy projects that passed through a competitive selection and gained the right to get a partial compensation for the construction and commissioning costs of RES generating facilities in the electric power wholesale market zone. The informational background for the study is corporate reports of project promoters, analytical and information materials of the Association NP Market Council, and legal documents for the development of renewable energy. The methodological base of the study is a theory of learning curves that assumes that cost savings in the production of high-tech products depends on the production growth rate (economy of scale) and gaining manufacturing experience (learning by doing). The study has identified factors that have a positive and a negative impact on the implementation of RES projects. Improvement of promotion measures in the renewable energy development in Russia corresponding to the current socio-economic situation is proposed.

  16. Lipid Identification by Untargeted Tandem Mass Spectrometry Coupled with Ultra-High-Pressure Liquid Chromatography.

    PubMed

    Gugiu, Gabriel B

    2017-01-01

    Lipidomics refers to the large-scale study of lipids in biological systems (Wenk, Nat Rev Drug Discov 4(7):594-610, 2005; Rolim et al., Gene 554(2):131-139, 2015). From a mass spectrometric point of view, by lipidomics we understand targeted or untargeted mass spectrometric analysis of lipids using either liquid chromatography (LC) (Castro-Perez et al., J Proteome Res 9(5):2377-2389, 2010) or shotgun (Han and Gross, Mass Spectrom Rev 24(3):367-412, 2005) approaches coupled with tandem mass spectrometry. This chapter describes the former methodology, which is becoming rapidly the preferred method for lipid identification owing to similarities with established omics workflows, such as proteomics (Washburn et al., Nat Biotechnol 19(3):242-247, 2001) or genomics (Yadav, J Biomol Tech: JBT 18(5):277, 2007). The workflow described consists in lipid extraction using a modified Bligh and Dyer method (Bligh and Dyer, Can J Biochem Physiol 37(8):911-917, 1959), ultra high pressure liquid chromatography fractionation of lipid samples on a reverse phase C18 column, followed by tandem mass spectrometric analysis and in silico database search for lipid identification based on MSMS spectrum matching (Kind et al., Nat Methods 10(8):755-758, 2013; Yamada et al., J Chromatogr A 1292:211-218, 2013; Taguchi and Ishikawa, J Chromatogr A 1217(25):4229-4239, 2010; Peake et al., Thermoscientifices 1-3, 2015) and accurate mass of parent ion (Sud et al., Nucleic Acids Res 35(database issue):D527-D532, 2007; Wishart et al., Nucleic Acids Res 35(database):D521-D526, 2007).

  17. Probing dynamics of micro-magnets with multi-mode superconducting resonator

    NASA Astrophysics Data System (ADS)

    Golovchanskiy, I. A.; Abramov, N. N.; Stolyarov, V. S.; Shchetinin, I. V.; Dzhumaev, P. S.; Averkin, A. S.; Kozlov, S. N.; Golubov, A. A.; Ryazanov, V. V.; Ustinov, A. V.

    2018-05-01

    In this work, we propose and explore a sensitive technique for investigation of ferromagnetic resonance and corresponding magnetic properties of individual micro-scaled and/or weak ferromagnetic samples. The technique is based on coupling the investigated sample to a high-Q transmission line superconducting resonator, where the response of the sample is studied at eigen frequencies of the resonator. The high quality factor of the resonator enables sensitive detection of weak absorption losses at multiple frequencies of the ferromagnetic resonance. Studying the microwave response of individual micro-scaled permalloy rectangles, we have confirmed the superiority of fluxometric demagnetizing factor over the commonly accepted magnetometric one and have depicted the demagnetization of the sample, as well as magnetostatic standing wave resonance.

  18. Where technology does not go: specialised neonatal care in resource-poor and conflict-affected contexts

    PubMed Central

    van den Boogaard, W.; Van den Bergh, R.; Takarinda, K. C.; Martinez, P.; Bekouanebandi, J. G.; Javed, I.; Ndelema, B.; Lefèvre, A.; Khalid, G. G.; Zuniga, I.

    2017-01-01

    Setting: Although neonatal mortality is gradually decreasing worldwide, 98% of neonatal deaths occur in low- and middle-income countries, where hospital care for sick and premature neonates is often unavailable. Médecins Sans Frontières Operational Centre Brussels (MSF-OCB) managed eight specialised neonatal care units (SNCUs) at district level in low-resource and conflict-affected settings in seven countries. Objective: To assess the performance of the MSF SNCU model across different settings in Africa and Southern Asia, and to describe the set-up of eight SNCUs, neonate characteristics and clinical outcomes among neonates from 2012 to 2015. Design: Multicentric descriptive study. Results: The MSF SNCU model was characterised by an absence of high-tech equipment and an emphasis on dedicated nursing and medical care. Focus was on the management of hypothermia, hypoglycaemia, feeding support and early identification/treatment of infection. Overall, 11 970 neonates were admitted, 41% of whom had low birthweight (<2500 g). The main diagnoses were low birthweight, asphyxia and neonatal infections. Overall mortality was 17%, with consistency across the sites. Chances of survival increased with higher birthweight. Conclusion: The standardised SNCU model was implemented across different contexts and showed in-patient outcomes within acceptable limits. Low-tech medical care for sick and premature neonates can and should be implemented at district hospital level in low-resource settings. PMID:28695092

  19. Bacterial toxicity comparison between nano- and micro-scaled oxide particles.

    PubMed

    Jiang, Wei; Mashayekhi, Hamid; Xing, Baoshan

    2009-05-01

    Toxicity of nano-scaled aluminum, silicon, titanium and zinc oxides to bacteria (Bacillus subtilis, Escherichia coli and Pseudomonas fluorescens) was examined and compared to that of their respective bulk (micro-scaled) counterparts. All nanoparticles but titanium oxide showed higher toxicity (at 20 mg/L) than their bulk counterparts. Toxicity of released metal ions was differentiated from that of the oxide particles. ZnO was the most toxic among the three nanoparticles, causing 100% mortality to the three tested bacteria. Al(2)O(3) nanoparticles had a mortality rate of 57% to B. subtilis, 36% to E. coli, and 70% to P. fluorescens. SiO(2) nanoparticles killed 40% of B. subtilis, 58% of E. coli, and 70% of P. fluorescens. TEM images showed attachment of nanoparticles to the bacteria, suggesting that the toxicity was affected by bacterial attachment. Bacterial responses to nanoparticles were different from their bulk counterparts; hence nanoparticle toxicity mechanisms need to be studied thoroughly.

  20. Broadband VHF Interferometer Observations of an Energetic In-cloud Pulse (EIP)

    NASA Astrophysics Data System (ADS)

    Tilles, J.; Krehbiel, P. R.; Stanley, M. A.; Rison, W.; Lyu, F.; Cummer, S.; Liu, N.; Dwyer, J. R.; Brown, R. G.; Wilson, J. G.

    2017-12-01

    Energetic in-cloud pulses (EIPs) are a little-known in-cloud subprocess of lightning. While they may be best identified by their large peak current (>200 kA) [Lyu et al., Geophys. Res. Lett., 42, 2015], they differ from narrow bipolar events (NBEs) - another type of in-cloud, high peak-current process - in that the sferic of an EIP lasts an order of magnitude longer ( ˜100 us) than that of a typical NBE ( ˜10 us). To further differentiate them from NBEs, EIPs are generally embedded within other electrical activity, whereas NBEs are known to primarily occur in isolation or as a lightning-initiating event [Smith et al., J. Geophys. Res., 104, D4, 4189-4212, 1999; Rison et al., Nat. Commun., 7, 10721, 2016]. Moreover, EIPs may have an intrinsic connection with the production of terrestrial gamma ray flashes (TGFs) [Cummer et al., Geophys. Res. Lett., 41, 8586-8593, 2014].Here we present coincident broadband VHF interferometer (INTF) observations and electric and magnetic field waveforms of an EIP with an associated NLDN peak current of 247 kA. The EIP occurs nearly 4 ms into a normal-polarity intracloud flash as part of the upward extension of the negative-polarity lightning leader. For this reason, we suspect that EIPs are a more energetic version of initial breakdown pulses (IBPs), which accompany the development of negative stepped leaders [e.g. Marshall et al., J. Geophys. Res. Atmos., 119, 445-460, 2014]. In addition, we show similarities with NBE-producing fast breakdown [Rison et al., 2016; Tilles et al., AE12A-03, AGU Fall Meeting, 2016], in that the breakdown accompanying the EIP propagates over a similar vertical extent ( ˜0.5-1 km) and with similar propagation speed ( ˜3×107 m/s). The INTF was developed by New Mexico Tech and has been deployed at Kennedy Space Center since July 2016. It employed three 100-m baselines in 2016, has a bandwidth of 14-88 MHz and samples at 180 MS/s with 16-bit resolution. A synchronously digitized fast antenna (FA), with 100-μ s decay time constant, samples the electric field, and the whole INTF+FA system is automatically triggered on strong VHF radiation. Coincident VLF/ LF (1-300 kHz, sampled at 1 MS/s) observations are made with Duke University's magnetic sensor network.

  1. Robotic technology evolution and transfer

    NASA Technical Reports Server (NTRS)

    Marzwell, Neville I.

    1992-01-01

    A report concerning technology transfer in the area of robotics is presented in vugraph form. The following topics are discussed: definition of technology innovation and tech-transfer; concepts relevant for understanding tech-transfer; models advanced to portray tech-transfer process; factors identified as promoting tech-transfer; factors identified as impeding tech-transfer; what important roles do individuals fulfill in tech-transfer; federal infrastructure for promoting tech-transfer; federal infrastructure for promoting tech-transfer; robotic technology evolution; robotic technology transferred; and recommendations for successful robotics tech-transfer.

  2. Occupational Field 66 (Avionics) Less MOS’s 6682, 6683 and 6689 Task Analysis.

    DTIC Science & Technology

    1979-04-01

    EQUIPMENT ( SACE ) TECH 011 ACFT CRYPTOGRAPHIC SYS TECI-, IMA 018 ACFT INERTIAL NAVIGATION SYSTEM (INS) SACE TECH 019 ACFT SEARCH/TRACK (SIT) SACE TECH...020 SACE SYS TECH 021 ACFT DECEPTIVE ELECTRONIC COUNTERMEASURES IDECM) TECH 022 ELECTRONIC COUNTERMEASURES (ECM) MODULE REPAIR TECH 023 ACFT ECM TECH

  3. Reinforcing Natural Rubber with Cellulose Nanofibrils Extracted from Bleached Eucalyptus Kraft Pulp

    Treesearch

    Chunmei Zhang; Tianliang Zhai; Ronald Sabo; Craig Clemons; Yi Dan; Lih-Sheng Turng

    2014-01-01

    Reinforced natural rubber (NR) nanocomposites were prepared by solution mixing, casting, and evaporation of pre-vulcanized natural rubber latex and an aqueous suspension of cellulose nanofibrils (CNFs) extracted from bleached eucalyptus kraft pulp. Scanning electron microscopy (SEM) images showed that there were no micro-scaled aggregates observed in the nanocomposites...

  4. FIB preparation of a NiO Wedge-Lamella and STEM X-ray microanalysis for the determination of the experimental k(O-Ni) Cliff-Lorimer coefficient.

    PubMed

    Armigliato, Aldo; Frabboni, Stefano; Gazzadi, Gian Carlo; Rosa, Rodolfo

    2013-02-01

    A method for the fabrication of a wedge-shaped thin NiO lamella by focused ion beam is reported. The starting sample is an oxidized bulk single crystalline, <100> oriented, Ni commercial standard. The lamella is employed for the determination, by analytical electron microscopy at 200 kV of the experimental k(O-Ni) Cliff-Lorimer (G. Cliff & G.W. Lorimer, J Microsc 103, 203-207, 1975) coefficient, according to the extrapolation method by Van Cappellen (E. Van Cappellen, Microsc Microstruct Microanal 1, 1-22, 1990). The result thus obtained is compared to the theoretical k(O-Ni) values either implemented into the commercial software for X-ray microanalysis quantification of the scanning transmission electron microscopy/energy dispersive spectrometry equipment or calculated by the Monte Carlo method. Significant differences among the three values are found. This confirms that for a reliable quantification of binary alloys containing light elements, the choice of the Cliff-Lorimer coefficients is crucial and experimental values are recommended.

  5. Tech Prep Marketing Guide. The Complete Book of Strategies and Practical Experiences.

    ERIC Educational Resources Information Center

    Williamson, Patty

    This guide explains the concept of marketing tech prep and provides marketing principles and strategies to promote tech prep programs. The guide covers the following topics: (1) why it is necessary to market tech prep; (2) what a comprehensive tech prep marketing plan should include; (3) targeting the benefits message; (4) marketing tech prep to…

  6. Biocompatibility and mechanical properties of diamond-like coatings on cobalt-chromium-molybdenum steel and titanium-aluminum-vanadium biomedical alloys.

    PubMed

    Hinüber, C; Kleemann, C; Friederichs, R J; Haubold, L; Scheibe, H J; Schuelke, T; Boehlert, C; Baumann, M J

    2010-11-01

    Diamond-like carbon (DLC) films are favored for wear components because of diamond-like hardness, low friction, low wear, and high corrosion resistance (Schultz et al., Mat-wiss u Werkstofftech 2004;35:924-928; Lappalainen et al., J Biomed Mater Res B Appl Biomater 2003;66B:410-413; Tiainen, Diam Relat Mater 2001;10:153-160). Several studies have demonstrated their inertness, nontoxicity, and the biocompatibility, which has led to interest among manufacturers of surgical implants (Allen et al., J Biomed Mater Res B Appl Biomater 2001;58:319-328; Uzumaki et al., Diam Relat Mater 2006;15:982-988; Hauert, Diam Relat Mater 2003;12:583-589; Grill, Diam Relat Mater 2003;12:166-170). In this study, hydrogen-free amorphous, tetrahedrally bonded DLC films (ta-C) were deposited at low temperatures by physical vapor deposition on medical grade Co28Cr6Mo steel and the titanium alloy Ti6Al4V (Scheibe et al., Surf Coat Tech 1996;85:209-214). The mechanical performance of the ta-C was characterized by measuring its surface roughness, contact angle, adhesion, and wear behavior, whereas the biocompatibility was assessed by osteoblast (OB) attachment and cell viability via Live/Dead assay. There was no statistical difference found in the wettability as measured by contact angle measurements for the ta-C coated and the uncoated samples of either Co28Cr6Mo or Ti6Al4V. Rockwell C indentation and dynamic scratch testing on 2-10 μm thick ta-C films on Co28Cr6Mo substrates showed excellent adhesion with HF1 grade and up to 48 N for the critical load L(C2) during scratch testing. The ta-C coating reduced the wear from 3.5 × 10(-5) mm(3)/Nm for an uncoated control sample (uncoated Co28Cr6Mo against uncoated stainless steel) to 1.1 × 10(-7) mm(3)/Nm (coated Co28Cr6Mo against uncoated stainless steel) in reciprocating pin-on-disk testing. The lowest wear factor of 3.9 × 10(-10) mm(3)/Nm was measured using a ta-C coated steel ball running against a ta-C coated and polished Co28Cr6Mo disk. Student's t-test found that the ta-C coating had no statistically significant (p < 0.05) effect on OB attachment, when compared with the uncoated control samples. There was no significant difference (p < 0.05) in the Live/Dead assay results in cell death between the ta-C coated Co28Cr6Mo and Ti6Al4V samples and the uncoated controls. Therefore, these ta-C coatings show improved wear and corrosion (Dorner-Reisel et al., Diam Relat Mater 2003;11:823-827; Affato et al., J Biomed Mater Res B Appl Biomater 2000;53:221-226; Dorner-Reisel et al., Surf Coat Tech 2004;177-178:830-837; Kim et al., Diam Relat Mater 2004;14:35-41) performance and excellent in vitro cyto-compatibility, when compared with currently used uncoated Co28Cr6Mo and Ti6Al4V implant materials.

  7. Application of microtremor horizontal-to-vertical spectral ratio (MHVSR) analysis for site characterization: State of the art

    USGS Publications Warehouse

    Molnar, S.; Cassidy, J. F.; Castellaro, S.; Cornou, C.; Crow, H.; Hunter, J. A.; Matsushima, S.; Sanchez-Sesma, F. J.; Yong, Alan

    2018-01-01

    Nakamura (Q Rep Railway Tech Res Inst 30:25–33, 1989) popularized the application of the horizontal-to-vertical spectral ratio (HVSR) analysis of microtremor (seismic noise or ambient vibration) recordings to estimate the predominant frequency and amplification factor of earthquake shaking. During the following quarter century, popularity in the microtremor HVSR (MHVSR) method grew; studies have verified the stability of a site’s MHVSR response over time and validated the MHVSR response with that of earthquake HVSR response. Today, MHVSR analysis is a popular reconnaissance tool used worldwide for seismic microzonation and earthquake site characterization in numerous regions, specifically, in the mapping of site period or fundamental frequency and inverted for shear-wave velocity depth profiles, respectively. However, the ubiquity of MHVSR analysis is predominantly a consequence of its ease in application rather than our full understanding of its theory. We present the state of the art in MHVSR analyses in terms of the development of its theoretical basis, current state of practice, and we comment on its future for applications in earthquake site characterization.

  8. Application of Microtremor Horizontal-to-Vertical Spectral Ratio (MHVSR) Analysis for Site Characterization: State of the Art

    NASA Astrophysics Data System (ADS)

    Molnar, S.; Cassidy, J. F.; Castellaro, S.; Cornou, C.; Crow, H.; Hunter, J. A.; Matsushima, S.; Sánchez-Sesma, F. J.; Yong, A.

    2018-03-01

    Nakamura (Q Rep Railway Tech Res Inst 30:25-33, 1989) popularized the application of the horizontal-to-vertical spectral ratio (HVSR) analysis of microtremor (seismic noise or ambient vibration) recordings to estimate the predominant frequency and amplification factor of earthquake shaking. During the following quarter century, popularity in the microtremor HVSR (MHVSR) method grew; studies have verified the stability of a site's MHVSR response over time and validated the MHVSR response with that of earthquake HVSR response. Today, MHVSR analysis is a popular reconnaissance tool used worldwide for seismic microzonation and earthquake site characterization in numerous regions, specifically, in the mapping of site period or fundamental frequency and inverted for shear-wave velocity depth profiles, respectively. However, the ubiquity of MHVSR analysis is predominantly a consequence of its ease in application rather than our full understanding of its theory. We present the state of the art in MHVSR analyses in terms of the development of its theoretical basis, current state of practice, and we comment on its future for applications in earthquake site characterization.

  9. Application of Microtremor Horizontal-to-Vertical Spectral Ratio (MHVSR) Analysis for Site Characterization: State of the Art

    NASA Astrophysics Data System (ADS)

    Molnar, S.; Cassidy, J. F.; Castellaro, S.; Cornou, C.; Crow, H.; Hunter, J. A.; Matsushima, S.; Sánchez-Sesma, F. J.; Yong, A.

    2018-07-01

    Nakamura (Q Rep Railway Tech Res Inst 30:25-33, 1989) popularized the application of the horizontal-to-vertical spectral ratio (HVSR) analysis of microtremor (seismic noise or ambient vibration) recordings to estimate the predominant frequency and amplification factor of earthquake shaking. During the following quarter century, popularity in the microtremor HVSR (MHVSR) method grew; studies have verified the stability of a site's MHVSR response over time and validated the MHVSR response with that of earthquake HVSR response. Today, MHVSR analysis is a popular reconnaissance tool used worldwide for seismic microzonation and earthquake site characterization in numerous regions, specifically, in the mapping of site period or fundamental frequency and inverted for shear-wave velocity depth profiles, respectively. However, the ubiquity of MHVSR analysis is predominantly a consequence of its ease in application rather than our full understanding of its theory. We present the state of the art in MHVSR analyses in terms of the development of its theoretical basis, current state of practice, and we comment on its future for applications in earthquake site characterization.

  10. The Texas Tech Prep Consortia: Strategies for Advancing Academic and Technical Education.

    ERIC Educational Resources Information Center

    Hensley, Oliver D., Ed.; And Others

    This book contains 30 chapters on the tech prep initiative in Texas: "The Identity of Tech Prep in Texas" (Tunstall); "A Snap-Shot of the Impact of the Tech Prep Initiative in the Governor's 24 Planning Regions" (Brown); "The Tech Prep Consortium Directors: The Architects for the Future of Texas" (Hensley et al.);…

  11. Tech Prep Implementation in the United States: The Once and Future Role of Community Colleges.

    ERIC Educational Resources Information Center

    Bragg, Debra D.; Layton, James D.

    1995-01-01

    Describes a study examining the impact of the Tech Prep Education Act on the initial implementation of federally supported Tech Prep Initiatives. Based on telephone survey responses from all 50 state Tech Prep leaders, reviews findings concerning the funding of Tech Prep consortia, state and local administrative structures, policies and goals, and…

  12. Tech-Prep in New York State: Profiles of Four Diverse Programs.

    ERIC Educational Resources Information Center

    Frenkel, Michael W.; Brodsky, Stanley M.

    These case studies highlight the diversity of four tech programs that responded with a unique set of organizational policies and procedures to a unique set of challenges. The case study on City Tech Tech-Prep Consortium in Brooklyn focuses on three strategies: transition to City Tech program, postsecondary component, and program evaluation. The…

  13. Tech Prep Implementation and Preliminary Student Outcomes for Eight Local Tech Prep Consortia.

    ERIC Educational Resources Information Center

    Bragg, Debra D.; Dare, Donna E.; Reger, W. M., IV; Ovaice, Ghazala; Zamani, Eboni M.; Layton, James D.; Dornsife, Carolyn J.; Vallee, Manuel; Brown, Carrie H.; Orr, Margaret Terry

    The implementation and student outcomes of Tech Prep were examined in a study of eight consortia that represented a range of Tech Prep models and approaches in urban, suburban, and rural locations across the United States. Data were collected from the following sources: field visits; follow-up survey of Tech Prep participants and nonparticipants;…

  14. NASA Tech Briefs Index 1979. Volume 4, Nos. 1-4

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Tech Briefs are short announcements of new technology derived from the research and development activities of the National Aeronautics and Space Administration. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This Index to NASA Tech Briefs contains abstracts and four indexes -- subject, personal author, originating Center, and Tech Brief number -- for 1979 Tech Briefs.

  15. NASA Tech Briefs Index 1978. Volume 3, Nos. 1-4

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Tech Briefs are short announcements of new technology derived from the research and development activities of the National Aeronautics and Space Administration. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This Index to NASA Tech Briefs contains abstracts and four indexes -- subject, personal author, originating Center, and Tech Brief number -- for 1978 Tech Briefs.

  16. NASA Tech Briefs Index 1980. Volume 5, Nos. 1-4

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Tech Briefs are short announcements of new technology derived from the research and development activities of the National Aeronautics and Space Administration. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This Index to NASA Tech Briefs contains abstracts and four indexes -- subject,. personal author, originating Center, and Tech Brief number -- for 1980 Tech Briefs.

  17. Cumulative index to NASA Tech Briefs, 1970-1975. [bibliographies

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Tech briefs of technology derived from the research and development activities of the National Aeronautics and Space Administration are presented. Abstracts and indexes of subject, personal author, originating center, and tech brief number for the 1970-1975 tech briefs are presented.

  18. Research on the competitiveness of high-tech industries in northeast China

    NASA Astrophysics Data System (ADS)

    Liu, Lei; Wang, Yang; Wang, Ming-Quan; Xiao, Yan-Bo; Gao, Ming

    2017-06-01

    Based on characteristics of high-tech industry in Northeast China, high-tech industry competitiveness index system was developed, and the competitiveness of high-tech industry was evaluated through principal component analysis and location quotient method. The results showed that the scale of high-tech industry in Northeast China as a whole was small, and presented a decreasing trend for the proportion in the country. The competitiveness of high-tech industry in Northeast China lagged far behind that of the eastern and central regions. The high-tech industry competitiveness of Liaoning, Jilin and Heilongjiang provinces in China ranked 15, 19 and 21, respectively. The manufacture of medicine in Jilin province, and the manufacture of aircraft and spacecraft and the related equipment in Liaoning and Heilongjiang provinces had high competitive advantage, but the manufacture of electronic equipment and communication equipment and the manufacture of computers and office equipment was lack of competitiveness. The development suggestions were put forward to improve the competitiveness of high-tech industries in Northeast China.

  19. Illinois Tech Prep Planning Strategies.

    ERIC Educational Resources Information Center

    Illinois Univ., Urbana. Dept. of Vocational and Technical Education.

    This tech prep planning handbook is based on the research conducted at the Office of Community College Research and Leadership, University of Illinois at Urbana-Champaign. The study involved information gathering procedures at each of the 17 tech prep pilot sites about their planning activities. Seven sections are included: (1) tech prep in…

  20. Wide-Bandgap MOSFET Research with Virginia Tech Graduate Students |

    Science.gov Websites

    Advanced Manufacturing Research | NREL Wide Bandgap MOSFET Research with Virginia Tech Wide -Bandgap MOSFET Research with Virginia Tech Graduate Students Along with graduate student fellows from Virginia Tech, NREL is researching aspects related to the reliability and prognostics of power electronic

  1. Planning a Tech Prep Program in Hospitality. Final Report.

    ERIC Educational Resources Information Center

    Chicago City Colleges, IL. Chicago City-Wide Coll.

    A project conducted to establish tech prep articulation training agreements between City Colleges of Chicago and several public secondary schools is described in this report. Project activities were as follows: (1) developed a handbook to define the tech prep experience and guide committee members on how tech prep can be a valuable asset to…

  2. Evaluating and Improving Tech Prep: Development, Validation, and Results of the Minnesota Self-Assessment Model.

    ERIC Educational Resources Information Center

    Pucel, David J.; And Others

    1996-01-01

    The Minnesota Tech Prep Self-Evaluation System is a framework based on ideas from Deming, Juran, and the Baldridge award. Testing with 17 Minnesota tech prep consortia found it effective in identifying areas needing improvement and promoting dialog among those involved in tech prep implementation. (SK)

  3. Tech-Prep Competency Profiles within the Engineering Technologies Cluster.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 12 competency profiles for tech prep courses within the engineering technologies cluster. The document consists of the following sections: (1) systemic curriculum reform philosophy--Ohio's vision of tech prep and its six critical components; (2) an explanation of the process of developing the tech prep competencies; (3) a…

  4. 34 CFR 406.1 - What is the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What is the State-Administered Tech-Prep Education... (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.1 What is the State-Administered Tech-Prep Education Program? If the annual...

  5. NCRVE Change Agent. Shaping the Future of Vocational Education. Volume 4, 1994.

    ERIC Educational Resources Information Center

    NCRVE Change Agent, 1994

    1994-01-01

    The first of four issues in this volume consists of four review articles. "Tech Prep Quality" reviews a guide to total quality management and tech prep. "Specific, Ocean to Ocean" reviews a publication that identifies 10 preliminary plans for implementing tech prep. "...No Single Option" is about a monograph that evaluates tech prep and other…

  6. Selected Outcomes Related to Tech Prep Implementation by Illinois Consortia, 2001-2005

    ERIC Educational Resources Information Center

    Bragg, Debra D.; Kirby, Catherine; Zhu, Rongchun

    2006-01-01

    This report is the summary of key aspects of Tech Prep in Illinois over the five year period of 2001-2005 during which all Tech Prep consortia provided annual data based on federal legislative requirements and state-determined essential elements of successful programs. These annual Tech Prep reports enable local educators to monitor student…

  7. Alumni Giving at Arkansas Tech University: College Experiences and Motivations to Give as Predictors of Giving Behavior

    ERIC Educational Resources Information Center

    Lackie, Mary Bane

    2010-01-01

    The purpose of this study was to examine the characteristics of the "Lost Generation" alumni who ended their attendance or graduated from Arkansas Tech University (Tech) between January 1973 and December 1995 relating to their demographic characteristics, perceptions of college experiences, involvement with Tech after graduation, and attitudes…

  8. 77 FR 26588 - In the Matter of Recycle Tech, Inc.; Order of Suspension of Trading

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] In the Matter of Recycle Tech, Inc.; Order of Suspension of Trading May 2, 2012. It appears to the Securities and Exchange Commission that there is a lack of current and accurate information concerning the securities of Recycle Tech, Inc. (``Recycle Tech...

  9. Cost Reduction Through the Use of Additive Manufacturing (3d Printing) and Collaborative Product Life Cycle Management Technologies to Enhance the Navy’s Maintenance Programs

    DTIC Science & Technology

    2013-09-01

    the order from the DLA; convenes a meeting with tech librarians , engineers, machinists, quality assurance (QA) inspectors, and mechanics to assess...created, begins the in-house process. 3. Research of Technical Drawings The tech librarian reviews the applicable repository for any tech drawings...applicable to Widget A. If none are found, the tech librarian contacts the OEM and other D-Level activities to find out whether the tech drawing is out

  10. Disability Evaluation System Analysis and Research Annual Report 2017

    DTIC Science & Technology

    2017-11-20

    Amanda L. Kelley, MPH Program Manager, AMSARA Deputy Program Manager, AMSARA Contractor, ManTech Health Contractor, ManTech Health Christine...Toolin, MS Cordie K. Campbell, MPH Public Health Analyst, AMSARA Public Health Analyst, AMSARA Contractor, ManTech Health Contractor...ManTech Health Preventive Medicine Branch Walter Reed Army Institute of Research 503 Robert Grant Road, Forest Glen Annex Silver

  11. TechEdSat Nano-Satellite Series Fact Sheet

    NASA Technical Reports Server (NTRS)

    Murbach, Marcus; Martinez, Andres; Guarneros Luna, Ali

    2014-01-01

    TechEdSat-3p is the second generation in the TechEdSat-X series. The TechEdSat Series uses the CubeSat standards established by the California Polytechnic State University Cal Poly), San Luis Obispo. With typical blocks being constructed from 1-unit (1U 10x10x10 cm) increments, the TechEdSat-3p has a 3U volume with a 30 cm length. The project uniquely pairs advanced university students with NASA researchers in a rapid design-to-flight experience lasting 1-2 semesters.The TechEdSat Nano-Satellite Series provides a rapid platform for testing technologies for future NASA Earth and planetary missions, as well as providing students with an early exposure to flight hardware development and management.

  12. Yttrium recovery from primary and secondary sources: A review of main hydrometallurgical processes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Innocenzi, Valentina, E-mail: valentina.innocenzi1@univaq.it; De Michelis, Ida; Kopacek, Bernd

    2014-07-15

    Highlights: • Review of the main hydrometallurgical processes to recover yttrium. • Recovery of yttrium from primary sources. • Recovery of yttrium from e-waste and other types of waste. - Abstract: Yttrium is important rare earths (REs) used in numerous fields, mainly in the phosphor powders for low-energy lighting. The uses of these elements, especially for high-tech products are increased in recent years and combined with the scarcity of the resources and the environmental impact of the technologies to extract them from ores make the recycling waste, that contain Y and other RE, a priority. The present review summarized themore » main hydrometallurgical technologies to extract Y from ores, contaminated solutions, WEEE and generic wastes. Before to discuss the works about the treatment of wastes, the processes to retrieval Y from ores are discussed, since the processes are similar and derived from those already developed for the extraction from primary sources. Particular attention was given to the recovery of Y from WEEE because the recycle of them is important not only for economical point of view, considering its value, but also for environmental impact that this could be generated if not properly disposal.« less

  13. 34 CFR 406.31 - How does a State carry out the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false How does a State carry out the State-Administered Tech... TECH-PREP EDUCATION PROGRAM What Conditions Must Be Met After a State Receives an Award? § 406.31 How does a State carry out the State-Administered Tech-Prep Education Program? (a) A State board carries...

  14. Evidence-Based Design for Project-Based Learning: A Case Study for a 50,000 SF Addition Dedicated to the New Tech Curriculum

    ERIC Educational Resources Information Center

    Moretti, Richard D.; Conte, Philip R.

    2012-01-01

    The Seaford School District, Seaford, Delaware, determined that a component of their "reinvention" of Seaford High School would be the creation of a New Tech Academy, affiliated with the New Tech Network and housed in an addition to that building. The New Tech Network, headquartered in Napa, California, is a rapidly growing association…

  15. Adapted managerial mathematical model to study the functions and interactions between enterprises in high-tech cluster

    NASA Astrophysics Data System (ADS)

    Anguelov, Kiril P.; Kaynakchieva, Vesela G.

    2017-12-01

    The aim of the current study is to research and analyze Adapted managerial mathematical model to study the functions and interactions between enterprises in high-tech cluster, and his approbation in given high-tech cluster; to create high-tech cluster, taking into account the impact of relationships between individual units in the cluster-Leading Enterprises, network of Enterprises subcontractors, economic infrastructure.

  16. Communications for Lifelong Success I and II (Tech Prep English I and II). Pilot Test Materials for Pendleton High School, Pendleton, South Carolina. Draft.

    ERIC Educational Resources Information Center

    Turlington, Anita; And Others

    These instructional materials include six supplementary units for Tech Prep English I (grade 9) and six assignments for Tech Prep English II (grade 10). The Tech Prep English I units have these components: unit objectives, introduction, and follow-up exercises. Topics include goal setting, problem solving and decision making, listening and reading…

  17. Pharmacist and Technician Perceptions of Tech-Check-Tech in Community Pharmacy Practice Settings.

    PubMed

    Frost, Timothy P; Adams, Alex J

    2018-04-01

    Tech-check-tech (TCT) is a practice model in which pharmacy technicians with advanced training can perform final verification of prescriptions that have been previously reviewed for appropriateness by a pharmacist. Few states have adopted TCT in part because of the common view that this model is controversial among members of the profession. This article aims to summarize the existing research on pharmacist and technician perceptions of community pharmacy-based TCT. A literature review was conducted using MEDLINE (January 1990 to August 2016) and Google Scholar (January 1990 to August 2016) using the terms "tech* and check," "tech-check-tech," "checking technician," and "accuracy checking tech*." Of the 7 studies identified we found general agreement among both pharmacists and technicians that TCT in community pharmacy settings can be safely performed. This agreement persisted in studies of theoretical TCT models and in studies assessing participants in actual community-based TCT models. Pharmacists who had previously worked with a checking technician were generally more favorable toward TCT. Both pharmacists and technicians in community pharmacy settings generally perceived TCT to be safe, in both theoretical surveys and in surveys following actual TCT demonstration projects. These perceptions of safety align well with the actual outcomes achieved from community pharmacy TCT studies.

  18. Get on Board the Cost Effective Way: A Tech Prep Replication Process.

    ERIC Educational Resources Information Center

    Moore, Wayne A.; Szul, Linda F.; Rivosecchi, Karen

    1997-01-01

    The Northwestern Pennsylvania Tech Prep Consortium model for replicating tech prep programs includes these steps: fact finding, local industry analysis, curriculum development, detailed description, marketing strategies, implementation, and program evaluation. (SK)

  19. Toward healthy prisons: the TECH model and its applications.

    PubMed

    Ross, Michael W; Jo Harzke, Amy

    2012-01-01

    This paper aims to explore how the TECH Model (testing for and treating infectious diseases and vaccination; environmental modification to prevent disease transmission; chronic disease identification and treatment; and health maintenance and education) can be used for assessing and achieving healthy prisons. This paper explores the concepts of "health in prison" and "healthy prisons" in the context of recent research and guidance. The paper then considers the TECH Model as an approach to achieving healthy prisons. Under each of the four TECH Model domains are tasks to achieve a healthy prison. For prisons with poor or no resources, each domain contains steps that will improve prison health and move towards a healthy prison for both prisoners and staff. Implementation can thus be "low-TECH" or "high-TECH" depending on the setting and the available resources and the model is specifically designed to provide options for resource-poor as well as resource-rich correctional settings. The TECH Model is a first step in characterizing the components of a healthy prison and the processes to achieve this. This Model could be implemented in all levels of prisons internationally.

  20. The ORNL Chemical Technology Division, 1950-1994

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jolley, R.L.; Genung, R.K.; McNeese, L.E.

    1994-10-01

    This document attempts to reconstruct the role played by the Chemical Technology Division (Chem Tech) of the Oak Ridge National Laboratory (ORNL) in the atomic era since the 1940`s related to the development and production of nuclear weapons and power reactors. Chem Tech`s early contributions were landmark pioneering studies. Unknown and dimly perceived problems like chemical hazards, radioactivity, and criticality had to be dealt with. New chemical concepts and processes had to be developed to test the new theories being developed by physicists. New engineering concepts had to be developed and demonstrated in order to build facilities and equipment thatmore » had never before been attempted. Chem Tech`s role was chemical separations, especially uranium and plutonium, and nuclear fuel reprocessing. With diversification of national and ORNL missions, Chem Tech undertook R&D studies in many areas including biotechnology; clinical and environmental chemistry; nuclear reactors; safety regulations; effective and safe waste management and disposal; computer modeling and informational databases; isotope production; and environmental control. The changing mission of Chem Tech are encapsulated in the evolving activities.« less

  1. NASA Tech Briefs, April 1999. Volume 23, No. 4

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Topics include: special coverage sections on automotive technology, and CAM and sections on electronic components and systems, software, materials, machinery/automation, physical sciences, and a special section of Electronic Tech Briefs and Motion Control Tech Briefs.

  2. NASA Tech Briefs, December 2000. Volume 24, No. 12

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Topics include: special coverage sections on Imaging/Video/Display Technology, and sections on electronic components and systems, test and measurement, software, information sciences, and special sections of Electronics Tech Briefs and Motion Control Tech Briefs.

  3. NASA Tech Briefs, October 2001. Volume 25, No. 10

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage section on composites and plastics, electronic components and systems, software, mechanics, physical sciences, information sciences, book and reports, and a special sections of Photonics Tech Briefs and Motion Control Tech Briefs.

  4. NASA Tech Briefs, February 2002. Volume 26, No. 2

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include:a technology focus on computers, electronic components and systems, software, materials, mechanics,physical sciences machinery, manufacturing/fabrication, mathematics, book and reports, motion control tech briefs and a special section on Photonics Tech Briefs.

  5. How To Implement a Tech Prep Program Based on the Rhode Island Model. Tech Prep Associate Degree Program. Technical Programs. Business/Office Administration Programs. Allied Health/Dental Health Programs.

    ERIC Educational Resources Information Center

    Community Coll. of Rhode Island, Warwick.

    This implementation guide contains information based on experiences that occurred during the development and implementation of the Rhode Island Tech Prep Model. It is intended to assist educators in addressing challenges and obstacles faced by the program early in the planning process. It begins with a rationale for tech prep. Rhode Island…

  6. Digital Logistics

    DTIC Science & Technology

    2000-03-17

    There will also be instances when we will need to take advantage of technological leaps made by our allies. The ’clash’ of high tech with low tech ...must be considered, especially as we move toward very high tech solutions to our military needs. The end goal is to create Army Forces that are...effect that science and technology today distort the military by substituting high - tech weapons that do not always work for more basic military

  7. a Study on the Document Information Service of the National Agricultural Library for Agricultural Sci-Tech Innovation in China

    NASA Astrophysics Data System (ADS)

    Xu, Qian; Meng, Xianxue

    This paper presents the significant function of the Chinese National Agricultural Library (CNAL) in the agricultural sci-tech innovation system in China, analyses the development of collection and service in the CNAL, explores the challenge towards sustain and develop information services for the agricultural sci-tech research and innovation, at last proposes the strategy for sci-tech document information service development.

  8. Impact of newer self-monitoring technology and brief phone-based intervention on weight loss: a randomized pilot study

    PubMed Central

    Ross, Kathryn M.; Wing, Rena R.

    2016-01-01

    Objective Despite the proliferation of newer self-monitoring technology (e.g., activity monitors and smartphone apps), their impact on weight loss outside of structured in-person behavioral intervention is unknown. Methods A randomized, controlled pilot study was conducted to examine efficacy of self-monitoring technology, with and without phone-based intervention, on 6-month weight loss in adults with overweight and obesity. Eighty participants were randomized to receive standard self-monitoring tools (ST, n=26), technology-based self-monitoring tools (TECH, n=27), or technology-based tools combined with phone-based intervention (TECH+PHONE, n=27). All participants attended one introductory weight loss session and completed assessments at baseline, 3 months, and 6 months. Results Weight loss from baseline to 6 months differed significantly between groups p=.042; there was a trend for TECH+PHONE (−6.4±1.2kg) to lose more weight than ST (−1.3±1.2kg); weight loss in TECH (−4.1±1.4kg) was between ST and TECH+PHONE. Fewer ST (15%) achieved ≥5% weight losses compared to TECH and TECH+PHONE (44%), p=.039. Adherence to self-monitoring caloric intake was higher in TECH+PHONE than TECH or ST, ps<.05. Conclusion These results suggest use of newer self-monitoring technology plus brief phone-based intervention improves adherence and weight loss compared to traditional self-monitoring tools. Further research should determine cost-effectiveness of adding phone-based intervention when providing self-monitoring technology. PMID:27367614

  9. NASA Tech Briefs, September 1998. Volume 22, No. 9

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage on data acquisition, also, electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, physical sciences, information sciences, This issue contains a special sections of Electronics Tech Briefs and Motion Control Tech Briefs.

  10. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-05

    ... Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Tampa, Florida; Amended Certification Regarding... Business Networks Services, Inc., Order Management Division, Philadelphia, Pennsylvania and Verizon...

  11. 76 FR 68243 - Youth Leadership Program: TechGirls

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... DEPARTMENT OF STATE [Public Notice: 7671] Youth Leadership Program: TechGirls Overview Information Bureau of Educational and Cultural Affairs (ECA) Request for Grant Proposals: Youth Leadership Program... Cultural Affairs (ECA) announces an open competition for the new Youth Leadership Program ``TechGirls...

  12. Materials Evaluation in the Tri-Service Thermal Radiation Test Facility.

    DTIC Science & Technology

    1984-06-20

    CONTRACTORS (Continued) Science Applications Intl Corp Science Applications. Inc ATTN: S. Binninger ATTN: Tech Library Science Applications Intl Corp...Tech, Inc ATTN: Library Science Applications, Inc ATTN: Tech Library TRW Electronics & Defense Sector ATTN: h. Plows ATTN: B. Sussholtz ATTN: J

  13. "What I Did over My Summer Vacation..."

    ERIC Educational Resources Information Center

    Techniques: Making Education and Career Connections, 1997

    1997-01-01

    A tech prep summer camp was designed to give ninth graders a taste of tech prep before they were asked to choose a high school path. Parents were invited to dinner to learn about tech prep programs and their potential for successful careers. (JOW)

  14. LUVOIR Tech Notes

    NASA Technical Reports Server (NTRS)

    Bolcar, Matthew R.; Shaklan, Stuart; Roberge, Aki; Rioux, Norman; Feinberg, Lee; Werner, Michael; Rauscher, Bernard; Mandell, Avi; France, Kevin; Schiminovich, David

    2016-01-01

    We present nine "tech notes" prepared by the Large UV/Optical/Infrared (LUVOIR) Science and Technology Definition Team (STDT), Study Office, and Technology Working Group. These tech notes are intended to highlight technical challenges that represent boundaries in the trade space for developing the LUVOIR architecture that may impact the science objectives being developed by the STDT. These tech notes are intended to be high-level discussions of the technical challenges and will serve as starting points for more in-depth analysis as the LUVOIR study progresses.

  15. Longitudinal analysis of high-technology medical services and hospital financial performance.

    PubMed

    Zengul, Ferhat D; Weech-Maldonado, Robert; Ozaydin, Bunyamin; Patrician, Patricia A; OʼConnor, Stephen J

    U.S. hospitals have been investing in high-technology medical services as a strategy to improve financial performance. Despite the interest in high-tech medical services, there is not much information available about the impact of high-tech services on financial performance. The aim of this study was to examine the impact of high-tech medical services on financial performance of U.S. hospitals by using the resource-based view of the firm as a conceptual framework. Fixed-effects regressions with 2 years lagged independent variables using a longitudinal panel sample of 3,268 hospitals (2005-2010). It was hypothesized that hospitals with rare or large numbers (breadth) of high-tech medical services will experience better financial performance. Fixed effects regression results supported the link between a larger breadth of high-tech services and total margin, but only among not-for-profit hospitals. Both breadth and rareness of high-tech services were associated with high total margin among not-for-profit hospitals. Neither breadth nor rareness of high-tech services was associated with operating margin. Although breadth and rareness of high-tech services resulted in lower expenses per inpatient day among not-for-profit hospitals, these lower costs were offset by lower revenues per inpatient day. Enhancing the breadth of high-tech services may be a legitimate organizational strategy to improve financial performance, especially among not-for-profit hospitals. Hospitals may experience increased productivity and efficiency, and therefore lower inpatient operating costs, as a result of newer technologies. However, the negative impact on operating revenue should caution hospital administrators about revenue reducing features of these technologies, which may be related to the payer mix that these technologies may attract. Therefore, managers should consider both the cost and revenue implications of these technologies.

  16. Biodegradation of tech-hexachlorocyclohexane in a upflow anaerobic sludge blanket (UASB) reactor.

    PubMed

    Bhat, Praveena; Kumar, M Suresh; Mudliar, Sandeep N; Chakrabarti, T

    2006-04-01

    Biodegradability of technical grade hexachlorocyclohexane (tech-HCH) was studied in an upflow anaerobic sludge blanket reactor (UASB) under continuous mode of operation in concentration range of 100-200 mg/l and constant HRT of 48 h. At steady state operation more than 85% removal of tech-HCH (upto 175 mg/l concentration) and complete disappearance of beta-HCH was observed. Kinetic constants in terms of maximum specific tech-HCH utilization rate (k) and half saturation velocity constant (K(L)) were found to be 11.88 mg/g/day and 8.11 mg/g/day, respectively. The tech-HCH degrading seed preparation, UASB reactor startup and degradation in continuous mode of operation of the reactor is presented in this paper.

  17. GT | Government & Community Relations | Georgia Institute of Technology |

    Science.gov Websites

    Atlanta, GA Skip to content Georgia Tech Georgia Institute of Technology Government & Georgia Tech's Impact State Relations Capitol Jackets Advocacy Network Legislative Priorities & ; Resources Georgia Legislative Internship Program Georgia Tech's Impact 2018 PHELAP Conference Community &

  18. NASA Tech Briefs, November 1998. Volume 22, No. 11

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage sections on test and measurement and sections on electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, physical sciences, information sciences, book and reports, and special sections of Electronics Tech Briefs amd Rapid Product Development Tech Briefs.

  19. A Mobile Phone Based Method to Assess Energy and Food Intake in Young Children: A Validation Study against the Doubly Labelled Water Method and 24 h Dietary Recalls.

    PubMed

    Delisle Nyström, Christine; Forsum, Elisabet; Henriksson, Hanna; Trolle-Lagerros, Ylva; Larsson, Christel; Maddison, Ralph; Timpka, Toomas; Löf, Marie

    2016-01-15

    Mobile phones are becoming important instruments for assessing diet and energy intake. We developed the Tool for Energy Balance in Children (TECH), which uses a mobile phone to assess energy and food intake in pre-school children. The aims of this study were: (a) to compare energy intake (EI) using TECH with total energy expenditure (TEE) measured via doubly labelled water (DLW); and (b) to compare intakes of fruits, vegetables, fruit juice, sweetened beverages, candy, ice cream, and bakery products using TECH with intakes acquired by 24 h dietary recalls. Participants were 39 healthy, Swedish children (5.5 ± 0.5 years) within the ongoing Mobile-based Intervention Intended to Stop Obesity in Preschoolers (MINISTOP) obesity prevention trial. Energy and food intakes were assessed during four days using TECH and 24 h telephone dietary recalls. Mean EI (TECH) was not statistically different from TEE (DLW) (5820 ± 820 kJ/24 h and 6040 ± 680 kJ/24 h, respectively). No significant differences in the average food intakes using TECH and 24 h dietary recalls were found. All food intakes were correlated between TECH and the 24 h dietary recalls (ρ = 0.665-0.896, p < 0.001). In conclusion, TECH accurately estimated the average intakes of energy and selected foods and thus has the potential to be a useful tool for dietary studies in pre-school children, for example obesity prevention trials.

  20. Tech Prep Compendium of Models. [Revised].

    ERIC Educational Resources Information Center

    Delaware Technical and Community Coll., Dover.

    This publication discusses four models for technical preparation (tech prep): program organization; student progress; tech prep data collection and evaluation model; and school/community. The program organization model is divided into four sections. Section I, the business industry, and labor section, shows the flow from craft committee and…

  1. NASA Tech Briefs, June 1998. Volume 22, No. 6

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage on computer hardware and peripherals, electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, manufacturing, physical sciences, information sciences, book and reports, and a special section of Photonics Tech Briefs. and a second special section of Motion Control Tech Briefs

  2. Health Technologies State Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This "tech prep" state competency profile contains all the competencies required and recommended for entry-level employees in occupations in the health technologies cluster. Introductory materials include the following: descriptions of the different types of competencies (essential ones that must be included in all new tech prep programs…

  3. NASA Tech Briefs, May 1999. Volume 23, No. 5

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Topics include: special coverage sections on sensors and composites and plastics, and sections on electronic components and systems, software, materials, mechanics, machinery and automation, bio-medical, physical sciences, book and reports, and a special section of Photonics Tech Briefs and Rapid Product Development Tech Briefs.

  4. NASA Tech Briefs, October 1999. Volume 23, No. 10

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Topics include: special coverage section on data acquisition and sensors and sections on electronic components and systems, software, materials, mechanics, machinery/automation, manufacturing/fabrication, bio-medical, physical sciences, information sciences, book and reports, and special section of Electronics Tech Briefs and Motion Control Tech briefs

  5. Planning a Successful Tech Show

    ERIC Educational Resources Information Center

    Nikirk, Martin

    2011-01-01

    Tech shows are a great way to introduce prospective students, parents, and local business and industry to a technology and engineering or career and technical education program. In addition to showcasing instructional programs, a tech show allows students to demonstrate their professionalism and skills, practice public presentations, and interact…

  6. Strategic directions and mechanisms in technology transfer

    NASA Technical Reports Server (NTRS)

    Mackin, Robert

    1992-01-01

    An outline summarizing the Working Panel discussion related to strategic directions for technology transfer is presented. Specific topics addressed include measuring success, management of technology, innovation and experimentation in the tech transfer process, integration of tech transfer into R&D planning, institutionalization of tech transfer, and policy/legislative resources.

  7. Adult Tech Prep.

    ERIC Educational Resources Information Center

    Schaad, Donna

    For over 2 years, Blak Hawk College (Illinois) has provided high school equivalency (GED) candidates and recipients, older returning students, and underprepared high school graduates with a Tech Prep curriculum to give them the skills to make the transition from adult basic education to college or work. The Adult Tech Prep (ATP) core curriculum…

  8. Promoting Tech Schools within Your Community

    ERIC Educational Resources Information Center

    Nikirk, Martin

    2010-01-01

    This article describes a number of promotional events and practices that the author's school engages in. The author hopes that his school's experiences will serve as an inspiration and useful model for other "Tech Directions" readers. There are many methods for successfully promoting one's tech program. Two key strategies are: (1) Connect in…

  9. Contextual Learning and Tech Prep Curriculum Integration.

    ERIC Educational Resources Information Center

    Edling, Walter

    Because tech prep has the twin goals of preparing students for entry into postsecondary/continuing education or the work force after high school, tech prep programs require significant modification of conventional curricula and teaching methodologies. Both research and experience have demonstrated that the ability to transfer learning from one…

  10. Minimizing Security Vulnerabilities in High-Tech Classrooms

    ERIC Educational Resources Information Center

    Ozkan, Betul C.; Gunay, Vedat

    2004-01-01

    Emerging technologies are quickly becoming part of daily learning and teaching endeavors in academia. Due to the access to certain high-tech tools educators must learn how to integrate these tools in educational settings. However, many also encounter problems and weaknesses in the same high-tech environment that uses and delivers information…

  11. NASA Tech Briefs, December 1998. Volume 22, No. 12

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage section on design and analysis software, and sections on electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, manufacturing/fabrication, physical sciences, and special sections of Photonics Tech Briefs, Motion Control Tech briefs and a Hot Technology File 1999 Resource Guide.

  12. NASA Tech Briefs, October 2000. Volume 24, No. 10

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Topics include: special coverage sections on CAD, CAE, and PDM, and, Composites and Plastics, and sections on electronic components and systems, software, test and measurement, mechanics, manufacturing/fabrication, physical sciences, information sciences, book and reports, and special sections of Electronics Tech Briefs and Motion Control Tech Briefs

  13. Tech-Prep Competency Profiles within the Business/Computer Technologies.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document, which is designed for educators throughout Ohio who are involved in planning and/or delivering tech prep programs within the business/computer technologies cluster, discusses and presents tech prep competency profiles (TCPs) for 12 business/computer technology occupations. The first part of the document contains the following:…

  14. 75 FR 76036 - American Axle & Manufacturing Detroit Manufacturing Complex Holbrook Avenue and Saint Aubin...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ... From Paint Tech International Detroit, MI; Amended Certification Regarding Eligibility To Apply for... firm. New information revealed that workers leased from Paint Tech International were employed on-site... certification to include workers leased from Paint Tech International working on-site at the Detroit, Michigan...

  15. Design Tech High School: d.tech

    ERIC Educational Resources Information Center

    EDUCAUSE, 2015

    2015-01-01

    A Bay Area charter high school, d.tech develops "innovation-ready" students by combining content knowledge with the design thinking process while fostering a sense of autonomy and purpose. The academic model is grounded in self-paced learning through a flex schedule, high standards, and design thinking through a four-year design…

  16. School-to-Work Apprenticeship. Project Manual 1993-1994.

    ERIC Educational Resources Information Center

    Lee Coll., Baytown, TX.

    With Perkins tech prep funds, Lee College (Baytown, Texas), working with the Gulf Coast Tech Prep Consortium and the Goose Creek Consolidated Independent School District, developed a school-to-work apprenticeship model for tech prep programs. An advisory committe provided guidance in identifying targeted apprenticeable jobs, program content, and…

  17. Understanding transferable supply chain lessons and practices to a "high-tech" industry using guidelines from a primary sector industry: a case study in the food industry supply chain.

    PubMed

    Coronado Mondragon, Adrian E; Coronado Mondragon, Christian E; Coronado, Etienne S

    2015-01-01

    Flexibility and innovation at creating shapes, adapting processes, and modifying materials characterize composites materials, a "high-tech" industry. However, the absence of standard manufacturing processes and the selection of materials with defined properties hinder the configuration of the composites materials supply chain. An interesting alternative for a "high-tech" industry such as composite materials would be to review supply chain lessons and practices in "low-tech" industries such as food. The main motivation of this study is to identify lessons and practices that comprise innovations in the supply chain of a firm in a perceived "low-tech" industry that can be used to provide guidelines in the design of the supply chain of a "high-tech" industry, in this case composite materials. This work uses the case study/site visit with analogy methodology to collect data from a Spanish leading producer of fresh fruit juice which is sold in major European markets and makes use of a cold chain. The study highlights supply base management and visibility/traceability as two elements of the supply chain in a "low-tech" industry that can provide guidelines that can be used in the configuration of the supply chain of the composite materials industry.

  18. Museum in a School (reaching the unreachable audience). Final report, February 2, 1993--December 14, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Diaz, O.

    SciTech, an interactive science and technology center located 45 miles west of Chicago, is dedicated to providing hands-on and minds-on experiences that explore the spectrum of science and mathematics. SciTech opened at its present location during the summer of 1990 in Aurora, a changing community with a large minority population. Since then, SciTech has received over 331,000 visitors from the entire Chicago metropolitan area. There are now more than 250 exhibits housed in the museum. SciTech has grown quickly in part due to the strong volunteer support from the research and development corridor population it serves, as well as throughmore » international ties. SciTech has become known as an innovative force in the science museum community for its original exhibits and unique youth and school programs. SciTech`s traveling outreach program, ``Museum in a School,`` has served over 391 public and private schools in 111 districts in the Chicago metropolitan area, and has reached over 3,099 teachers and 98,837 students throughout its history. This program serves a wide variety of students, including bilingual, economically depressed, and learning impaired. SciTech is concerned with every American`s need for increasing basic science literacy.« less

  19. Synergistic effect of PEGylated resveratrol on delivery of anticancer drugs.

    PubMed

    Wang, Wenlong; Zhang, Liang; Le, Yuan; Chen, Jian-Feng; Wang, Jiexin; Yun, Jimmy

    2016-02-10

    Resveratrol (RES) is a natural polyphenol which can be considered as a nutraceutical because of its benefits such as anticancer and antioxidant activity. In this paper, we designed polymer-RES conjugates as anticancer drug carrier for synergistic therapeutic effect in cancer treatment. Bicalutamide (BIC) was used as a model drug to investigate the drug release behaviors and in vitro anticancer performance. PEG-RES and PEG-Glycine-RES nanoparticles were prepared and characterized. The size of the prepared particles was around 50 nm with RES content of 17.2 and 16.3 wt% for PEG-RES and PEG-Glycine-RES, respectively, and BIC loading efficiency were of 81.6% and 84.5%, separately. Release rate of RES from conjugates depended on the stability of ester group against hydrolysis. BIC release was much faster than RES release. The anticancer activity of BIC loaded PEGylated RES nanoparticles was much better than that of free BIC, indicating the conjugates provided a synergetic cytotoxicity to cancer cells. Confocal laser scanning microscopy observation and flow cytometry analyses indicated that PEGylated RES conjugates were more efficiently internalized into cells, released drug into cytoplasm. These results suggest that PEGylated RES conjugates show great potential for cancer therapy. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Does the high–tech industry consistently reduce CO{sub 2} emissions? Results from nonparametric additive regression model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Bin; Research Center of Applied Statistics, Jiangxi University of Finance and Economics, Nanchang, Jiangxi 330013; Lin, Boqiang, E-mail: bqlin@xmu.edu.cn

    China is currently the world's largest carbon dioxide (CO{sub 2}) emitter. Moreover, total energy consumption and CO{sub 2} emissions in China will continue to increase due to the rapid growth of industrialization and urbanization. Therefore, vigorously developing the high–tech industry becomes an inevitable choice to reduce CO{sub 2} emissions at the moment or in the future. However, ignoring the existing nonlinear links between economic variables, most scholars use traditional linear models to explore the impact of the high–tech industry on CO{sub 2} emissions from an aggregate perspective. Few studies have focused on nonlinear relationships and regional differences in China. Basedmore » on panel data of 1998–2014, this study uses the nonparametric additive regression model to explore the nonlinear effect of the high–tech industry from a regional perspective. The estimated results show that the residual sum of squares (SSR) of the nonparametric additive regression model in the eastern, central and western regions are 0.693, 0.054 and 0.085 respectively, which are much less those that of the traditional linear regression model (3.158, 4.227 and 7.196). This verifies that the nonparametric additive regression model has a better fitting effect. Specifically, the high–tech industry produces an inverted “U–shaped” nonlinear impact on CO{sub 2} emissions in the eastern region, but a positive “U–shaped” nonlinear effect in the central and western regions. Therefore, the nonlinear impact of the high–tech industry on CO{sub 2} emissions in the three regions should be given adequate attention in developing effective abatement policies. - Highlights: • The nonlinear effect of the high–tech industry on CO{sub 2} emissions was investigated. • The high–tech industry yields an inverted “U–shaped” effect in the eastern region. • The high–tech industry has a positive “U–shaped” nonlinear effect in other regions. • The linear impact of the high–tech industry in the eastern region is the strongest.« less

  1. A Mobile Phone Based Method to Assess Energy and Food Intake in Young Children: A Validation Study against the Doubly Labelled Water Method and 24 h Dietary Recalls

    PubMed Central

    Delisle Nyström, Christine; Forsum, Elisabet; Henriksson, Hanna; Trolle-Lagerros, Ylva; Larsson, Christel; Maddison, Ralph; Timpka, Toomas; Löf, Marie

    2016-01-01

    Mobile phones are becoming important instruments for assessing diet and energy intake. We developed the Tool for Energy Balance in Children (TECH), which uses a mobile phone to assess energy and food intake in pre-school children. The aims of this study were: (a) to compare energy intake (EI) using TECH with total energy expenditure (TEE) measured via doubly labelled water (DLW); and (b) to compare intakes of fruits, vegetables, fruit juice, sweetened beverages, candy, ice cream, and bakery products using TECH with intakes acquired by 24 h dietary recalls. Participants were 39 healthy, Swedish children (5.5 ± 0.5 years) within the ongoing Mobile-based Intervention Intended to Stop Obesity in Preschoolers (MINISTOP) obesity prevention trial. Energy and food intakes were assessed during four days using TECH and 24 h telephone dietary recalls. Mean EI (TECH) was not statistically different from TEE (DLW) (5820 ± 820 kJ/24 h and 6040 ± 680kJ/24 h, respectively). No significant differences in the average food intakes using TECH and 24 h dietary recalls were found. All food intakes were correlated between TECH and the 24 h dietary recalls (ρ = 0.665–0.896, p < 0.001). In conclusion, TECH accurately estimated the average intakes of energy and selected foods and thus has the potential to be a useful tool for dietary studies in pre-school children, for example obesity prevention trials. PMID:26784226

  2. Virginia Tech Researchers Study Effects of Shootings on Their Campus

    ERIC Educational Resources Information Center

    Gravois, John

    2008-01-01

    This article reports how researchers at Virginia Tech, working in a variety of disciplines, are studying the long-term effects of the campus killings 10 months ago. After the killings, administrators at Virginia Tech realized that their normal institutional-review process for research proposals was not sufficient to deal with the likely onslaught…

  3. High Tech, Low Tech and Education. Sociology of the School.

    ERIC Educational Resources Information Center

    Watkins, Peter

    Designed to provide a link between academic thought and research and the practice of teaching, this monograph explores the appropriate educational response to technological change. The central argument of this study is that future job opportunities will lie essentially with low tech jobs, i.e., traditional, basic, industrial jobs, rather than the…

  4. School-to-Work Apprenticeship. Project Manual 1993-1995.

    ERIC Educational Resources Information Center

    Lee Coll., Baytown, TX.

    With 1993-94 and 1994-95 Perkins tech prep funds, Lee College, in cooperation with a consortium and local schools, planned, developed, and validated a school-to-work apprenticeship model for tech prep programs. The other educational partners were the Gulf Coast Tech Prep Consortium and nine high schools in eight area school districts. The…

  5. A Survey of Perceptions of the Virginia Tech Tragedy

    ERIC Educational Resources Information Center

    Fallahi, Carolyn R.; Austad, Carol Shaw; Fallon, Marianne; Leishman, Lisa

    2009-01-01

    The recent shootings at the Virginia Polytechnic Institute (Virginia Tech) shocked the nation and brought violence on college campuses to the forefront of the nation's attention. We surveyed college students and faculty/staff three weeks after the incident about their perceptions of the Virginia Tech shooting, subsequent media exposure, and school…

  6. Tech Prep SCANS Lesson Development. Region 10 Tech Prep.

    ERIC Educational Resources Information Center

    Region 10 Tech Prep Consortium, Bloomington, IN.

    This document contains 50 applications-based lessons developed during the 1993-94 school year as part of the Indiana Region 10 Tech Prep Project. The lessons were developed by 91 secondary and postsecondary educators and are modeled around the SCANS (Secretary's Commission on Achieving Necessary Skills) competencies. The applications-based lessons…

  7. Building 21st Century Schools: Designing Smarter, Sleeker High-Tech Facilities.

    ERIC Educational Resources Information Center

    Cutshall, Sandy

    2003-01-01

    The demand for high-tech programs in tandem with traditional classes challenges school districts to provide flexible facilities for career and technical education. Some districts partner with local businesses to develop state-of-the art facilities and deal with costs, upkeep, and upgrading. Some high-tech educational facilities are themselves…

  8. Soft Soil Tire Model Development and Experimental Testing

    DTIC Science & Technology

    2012-09-01

    Sandu 1 , Mr. Eduardo Pinto 2 , Mr. Scott Naranjo 3 , Dr. Paramsothy Jayakumar 4 , Dr. Brant Ross 5 1Virginia Tech, 2Virginia Tech, 3Virginia Tech...W56HZV-04-2-0001 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Corina Sandu; Eduardo Pinto; Scott Naranjo; Paramsothy Jayakumar ; Brant Ross

  9. Introduction to Vocations. High Tech Focus. Final Report 1984-85.

    ERIC Educational Resources Information Center

    Wayne Township Schools, NJ.

    This report contains the materials that were developed during a project to make middle-grade students more aware of high tech careers through the following activities: (1) teacher and student visitations of community sites to explore high tech careers in 15 occupational clusters; (2) exploratory activities to facilitate linkages and articulation…

  10. TechTrends 2010-2015: A Content Analysis

    ERIC Educational Resources Information Center

    Stauffer, Eric

    2017-01-01

    This study is a content analysis of articles published within the journal "TechTrends" from 2000 to 2015. The study reveals that the publication "TechTrends" has increased the overall number of peer reviewed original papers over the last 6 years. The author describes the proportion of these original papers per volume and…

  11. Project Georgia High School/High Tech

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The High School/High Tech initiative of the President's Committee on Employment of Disabilities, Georgia's application of the collaborative "Georgia Model" and NASA's commitment of funding have shown that opportunities for High School/High Tech students are unlimited. In Georgia, the partnership approach to meeting the needs of this program has opened doors previously closed. As the program grows and develops, reflecting the needs of our students and the marketplace, more opportunities will be available. Our collaboratives are there to provide these opportunities and meet the challenge of matching our students with appropriate education and career goals. Summing up the activities and outcomes of Project Georgia High School/High Tech is not difficult. Significant outcomes have already occurred in the Savannah area as a result of NASA's grant. The support of NASA has enabled Georgia Committee to "grow" High School/High Tech throughout the region-and, by example, the state. The success of the Columbus pilot project has fostered the proliferation of projects, resulting in more than 30 Georgia High School High Tech programs-with eight in the Savannah area.

  12. Is the Writing on the Wall for Tabletops?

    NASA Astrophysics Data System (ADS)

    Pantidi, Nadia; Rogers, Yvonne; Robinson, Hugh

    We describe an ethnographic study that explores how low tech and new tech surfaces support participation and collaboration during a workshop breakout session. The low tech surfaces were post-it notes and large sheets of paper. The new tech surfaces were writeable walls and a multi-touch tabletop. Four groups used the different surfaces during three phases: i) brief presentation of position papers and discussion of themes, ii) the creation of a group presentation and iii) a report back session. Participation and collaboration varied depending on the physical, technological and social factors at play when using the different surfaces. We discuss why this is the case, noting how new shareable surfaces may need to be constrained to invite participation in ways that are simply taken for granted because of their familiarity when using low tech materials.

  13. NASA Tech Briefs, April 1995. Volume 19, No. 4

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This issue of the NASA Tech Briefs has a special focus section on video and imaging, a feature on the NASA invention of the year, and a resource report on the Dryden Flight Research Center. The issue also contains articles on electronic components and circuits, electronic systems, physical sciences, materials, computer programs, mechanics, machinery, manufacturing/fabrication, mathematics and information sciences and life sciences. In addition to the standard articles in the NASA Tech brief, this contains a supplement entitled "Laser Tech Briefs" which features an article on the National Ignition Facility, and other articles on the use of Lasers.

  14. Effects of an Abbreviated Obesity Intervention Supported by Mobile Technology: The ENGAGED Randomized Clinical Trial

    PubMed Central

    Spring, Bonnie; Pellegrini, Christine A.; Pfammatter, Angela; Duncan, Jennifer M.; Pictor, Alex; McFadden, H. Gene; Siddique, Juned; Hedeker, Donald

    2017-01-01

    Objectives To determine the effects on weight loss of three abbreviated behavioral weight loss interventions with and without coaching and mobile technology. Methods Randomized controlled efficacy study of three six-month weight loss treatments delivered to 96 adults with obesity: 1) self-guided [SELF], 2) standard [STND], or 3) technology-supported [TECH]. STND and TECH received 8 in-person group treatment sessions. SELF and STND used paper diaries to self-monitor diet, activity, and weight; TECH used a smartphone application with social networking features and wireless accelerometer. Results Weight loss was greater for TECH and STND than SELF at 6 months [−5.7kg (95% CI: −7.2, −4.1) vs. −2.7kg (95% CI: −5.1, −0.3), p<.05]), but not 12 months. TECH and STND did not differ except that more STND (59%) than TECH (34%) achieved ≥5% weight loss at 6 months (P < 0.05). Self-monitoring adherence was greater in TECH than STND (P <0.001), greater in both interventions than SELF (P <0.001), and covaried with weight loss (r(84) = 0.36 − 0.51, P<.001). Conclusions Abbreviated behavioral counseling can produce clinically meaningful weight loss regardless of whether self-monitoring is performed on paper or smartphone, but long-term superiority over standard of care self-guided treatment is challenging to maintain. PMID:28494136

  15. Co-encapsulated resveratrol and quercetin in chitosan and peg modified chitosan nanoparticles: For efficient intra ocular pressure reduction.

    PubMed

    Natesan, Subramanian; Pandian, Saravanakumar; Ponnusamy, Chandrasekar; Palanichamy, Rajaguru; Muthusamy, Sivakumar; Kandasamy, Ruckmani

    2017-11-01

    Natural anti-oxidants resveratrol (RES) and quercetin (QUR) posses the ability to reduce intra ocular pressure efficiently. Concurrent administration of RES and QUR was able to enhance the bioavailability of RES. Present research work describes upsurge of QUR in RES loaded chitosan (CS) nanoparticles (NPs) and polyethylene glycol (PEG) modified CS NPs for improved delivery and synergic effects on reducing intra ocular pressure for the treatment of glaucoma. CS NPs and PEG modified CS NPs were prepared by ionic gelation of tripolyphosphate and CS. The synthesised NPs were spherical in shape and RES entrapment and loading efficiency in the formulation decreased with increasing PEG concentration. Particle size of the formulation increased while incorporating PEG and drugs. The crystalline nature of RES and QUR changed in the NPs and that was confirmed by XRD study. Free radical neutralising efficiency improved while incorporating QUR in the formulation. Ex-vivo corneal permeation of RES was higher from RES and QUR loaded formulation than RES alone containing NPs and free RES dispersion. RES and QUR loaded PEG modified CS NPs showed sustained and enhanced reduction of intra ocular pressure (5.5±0.5mmHg) in normotensive rabbits. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. AVA Guide to Federal Funding for Tech Prep.

    ERIC Educational Resources Information Center

    Brustein, Michael

    This handbook outlines the options and requirements for federal support for tech prep in the Perkins law. It explains what educators must do and not do to assure compliance with all the law's mandates and to avoid audit exceptions. The guide also covers new tech prep provisions that were included in the Higher Education Act of 1992. Discussed in…

  17. A User-Friendly Model for Business/Education Partnerships.

    ERIC Educational Resources Information Center

    Brooks, Gayle; Bell Carmine

    In an effort to ensure local business involvement, the Steering Committee of the Tech Prep Consortium at Pasco-Hernando Community College (PHCC) in Central Florida invited members of the local business community to a Tech Prep Kickoff luncheon to sell them on Tech Prep. A tremendous number of companies attended the meeting and, to focus the energy…

  18. Virginia Water Resources Research Center - at Virginia Tech since 1965

    Science.gov Websites

    Virginia Water Resources Research Center at Virginia Tech since 1965 Search for: Search Skip to collaborative research, extension, and education programs to develop solutions to water resource challenges. We Monitoring Council Conference: March 21, 2018 The Virginia Water Resources Research Center at Virginia Tech

  19. Turning Students into Employees: The School-to-Work Payoff.

    ERIC Educational Resources Information Center

    Center for Occupational Research and Development, Inc., Waco, TX.

    This booklet describes the success of tech prep under the federal school-to-work (STW) initiative and provides case studies showing how schools and businesses are using tech prep to create the world's best work force for the new millennium. The first section discusses the payoff from STW, and the second section describes tech prep. Section 3…

  20. Med-Tech Program. Tech Prep Final Report.

    ERIC Educational Resources Information Center

    Chicago Public Schools, IL.

    Staff from DuSable High School in Chicago, Illinois, collaborated with Malcolm X College and three area hospitals to develop a medical technician training program focusing on career awareness and development of the basic reading and math skills needed for any career. A 3-year Med Tech curriculum for grades 9, 10, and 11 and a career awareness…

  1. Igniting the Spark: Tech Trek STEM Camps for Girls. Summary of Survey Findings

    ERIC Educational Resources Information Center

    American Association of University Women, 2014

    2014-01-01

    Tech Trek opens up STEM possibilities for girls in many contexts. It expands and influences their academic and social lives, starting in middle school and continuing on into their careers. The program seeks out talented girls, sparks their interest, illuminates the value of a college education, and validates their passions. Tech Trek's exciting,…

  2. Report from the BIT's 4th Annual World Congress of High-Tech Acupuncture and Integrative Medicine Held in Xi'an, China, 25-27 September 2017.

    PubMed

    Litscher, Gerhard; Mei, Xiaodan

    2017-10-19

    High-tech acupuncture is an example of a very successful cross-over between tradition and innovation. "The Annual World Congress of High-Tech Acupuncture and Integrative Medicine" was successfully organized on four occasions, and attracted more than 800 participants from 55 countries [...].

  3. Virginia Tech Weighs Hundreds of Recommendations and Acts on Some

    ERIC Educational Resources Information Center

    Fischer, Karin

    2008-01-01

    Three reports on last April's shootings left Virginia Tech under a mountain of recommendations--roughly 400 in all. So far the university has dealt with some of the most significant ones. Virginia Tech established an emergency-notification system, created a team to assess at-risk students and employees, and hired additional police officers and…

  4. Connecting Teachers and Ed-Tech Developers: Lessons from NYC's "Gap App" Program. Report

    ERIC Educational Resources Information Center

    Villavicencio, Adriana; Siman, Nina; Lafayette, Camille; Kang, David

    2016-01-01

    In 2011, with support from a federal Investing in Innovation grant, the NYC Department of Education launched Innovate NYC Schools. The initiative was designed to address two, related challenges to effectively integrating education technology (ed-tech) into classrooms: First, procurement of ed-tech tools is often hampered by a disconnect between…

  5. Connecting Teachers and Ed-Tech Developers: Lessons from NYC's "Gap App" Program. Technical Appendices

    ERIC Educational Resources Information Center

    Villavicencio, Adriana; Siman, Nina; Lafayette, Camille; Kang, David

    2016-01-01

    In 2011, with support from a federal Investing in Innovation grant, the NYC Department of Education launched Innovate NYC Schools. The initiative was designed to address two, related challenges to effectively integrating education technology (ed-tech) into classrooms: First, procurement of ed-tech tools is often hampered by a disconnect between…

  6. 75 FR 19626 - Notice of Intent To Grant Exclusive Patent License: SciTech Medical Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... DEPARTMENT OF DEFENSE Department of the Navy Notice of Intent To Grant Exclusive Patent License: SciTech Medical Inc. AGENCY: Department of the Navy, DoD. ACTION: Notice. SUMMARY: The Department of the Navy hereby gives notice of its intent to grant a partially exclusive license to SciTech Medical...

  7. The Effect of Studying Tech Prep in High School and College Academic Performance

    ERIC Educational Resources Information Center

    Ray, Larry A.

    2011-01-01

    This study examined the academic performance of Tech Prep students (referred to as participants) in comparison to non-Tech Prep students (referred to as non-participants) entering a two-year community college from sixteen different high schools in Stark County, Ohio. This study provided a quantitative analysis of students' academic experiences to…

  8. The Debreather and NuTech: A Reply to Kleespies

    ERIC Educational Resources Information Center

    Ogden, Russel D.

    2010-01-01

    This article responds to Phillip Kleespies's (2010/this issue) commentary on NuTech fieldworkers and their use of the debreather. Non-medical assistance with suicide raises legitimate concerns about accountability, public safety, and care for those who are suffering. Given that suicide is not a crime, an outcome of the NuTech movement may be that…

  9. 75 FR 28656 - Amphenol Printed Circuits, Inc., a Subsidiary of Amphenol Corporation, Including On-Site Leased...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ..., MicoTech, and CoWorx, Nashua, NH; Amended Certification Regarding Eligibility To Apply for Worker... commercial products. The company reports that workers leased from Technical Needs, MicoTech, and CoWorx were... amending this certification to include workers leased from Technical Needs, MicoTech, and CoWorx working on...

  10. Impact of the Siena College Tech Valley Scholars Program on Student Outcomes

    ERIC Educational Resources Information Center

    Medsker, Larry; Allard, Lee; Tucker, Lucas J.; O'Donnell, Jodi L.; Sterne-Marr, Rachel; Bannon, Jon; Finn, Rose; Weatherwax, Allan

    2016-01-01

    The Tech Valley Scholars (TVS) program included 38 students who joined this program over the course of three academic years, from 2009 to 2012. These students comprise the experimental group for this study to determine if participating in the NSF-funded Tech Valley Scholars program improved academic outcomes. The experimental group was compared to…

  11. Virtual reality helmet display quality influences the magnitude of virtual reality analgesia.

    PubMed

    Hoffman, Hunter G; Seibel, Eric J; Richards, Todd L; Furness, Thomas A; Patterson, David R; Sharar, Sam R

    2006-11-01

    Immersive Virtual Reality (VR) distraction can be used in addition to traditional opioids to reduce procedural pain. The current study explored whether a High-Tech-VR helmet (ie, a 60-degree field-of-view head-mounted display) reduces pain more effectively than a Low-Tech-VR helmet (a 35-degree field-of-view head-mounted display). Using a double-blind between-groups design, 77 healthy volunteers (no patients) aged 18-23 were randomly assigned to 1 of 3 groups. Each subject received a brief baseline thermal pain stimulus, and the same stimulus again minutes later while in SnowWorld using a Low-Tech-VR helmet (Group 1), using a High-Tech-VR helmet (Group 2), or receiving no distraction (Group 3, control group). Each participant provided subjective 0-10 ratings of cognitive, sensory, and affective components of pain, and amount of fun during the pain stimulus. Compared to the Low-Tech-VR helmet group, subjects in the High-Tech-VR helmet group reported 34% more reduction in worst pain (P < .05), 46% more reduction in pain unpleasantness (P = .001), 29% more reduction in "time spent thinking about pain" (P < .05), and 32% more fun during the pain stimulus in VR (P < .05). Only 29% of participants in the Low-Tech helmet group, as opposed to 65% of participants in the High-Tech-VR helmet group, showed a clinically significant reduction in pain intensity during virtual reality. These results highlight the importance of using an appropriately designed VR helmet to achieve effective VR analgesia (see ). Pain during medical procedures (eg, burn wound care) is often excessive. Adjunctive virtual reality distraction can substantially reduce procedural pain. The results of the present study show that a higher quality VR helmet was more effective at reducing pain than a lower quality VR helmet.

  12. Technology Cost and Schedule Estimation (TCASE) Final Report

    NASA Technical Reports Server (NTRS)

    Wallace, Jon; Schaffer, Mark

    2015-01-01

    During the 2014-2015 project year, the focus of the TCASE project has shifted from collection of historical data from many sources to securing a data pipeline between TCASE and NASA's widely used TechPort system. TCASE v1.0 implements a data import solution that was achievable within the project scope, while still providing the basis for a long-term ability to keep TCASE in sync with TechPort. Conclusion: TCASE data quantity is adequate and the established data pipeline will enable future growth. Data quality is now highly dependent the quality of data in TechPort. Recommendation: Technology development organizations within NASA should continue to work closely with project/program data tracking and archiving efforts (e.g. TechPort) to ensure that the right data is being captured at the appropriate quality level. TCASE would greatly benefit, for example, if project cost/budget information was included in TechPort in the future.

  13. Drop-wise and film-wise water condensation processes occurring on metallic micro-scaled surfaces

    NASA Astrophysics Data System (ADS)

    Starostin, Anton; Valtsifer, Viktor; Barkay, Zahava; Legchenkova, Irina; Danchuk, Viktor; Bormashenko, Edward

    2018-06-01

    Water condensation was studied on silanized (superhydrophobic) and fluorinated (superoleophobic) micro-rough aluminum surfaces of the same topography. Condensation on superhydrophobic surfaces occurred via film-wise mechanism, whereas on superoleophobic surfaces it was drop-wise. The difference in the pathways of condensation was attributed to the various energy barriers separating the Cassie and Wenzel wetting states on the investigated surfaces. The higher barriers inherent for superoleophobic surfaces promoted the drop-wise condensation. Triple-stage kinetics of growth of droplets condensed on superoleophobic surfaces is reported and discussed.

  14. Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways

    PubMed Central

    Singh, Bhupendra; Shoulson, Rivka; Chatterjee, Anwesha; Ronghe, Amruta; Bhat, Nimee K.; Dim, Daniel C.; Bhat, Hari K.

    2014-01-01

    The importance of estrogens in the etiology of breast cancer is widely recognized. Estrogen-induced oxidative stress has been implicated in this carcinogenic process. Resveratrol (Res), a natural antioxidant phytoestrogen has chemopreventive effects against a variety of illnesses including cancer. The objective of the present study was to characterize the mechanism(s) of Res-mediated protection against estrogen-induced breast carcinogenesis. Female August Copenhagen Irish rats were treated with 17β-estradiol (E2), Res and Res + E2 for 8 months. Cotreatment of rats with Res and E2 inhibited E2-mediated proliferative changes in mammary tissues and significantly increased tumor latency and reduced E2-induced breast tumor development. Resveratrol treatment alone or in combination with E2 significantly upregulated expression of nuclear factor erythroid 2-related factor 2 (NRF2) in mammary tissues. Expression of NRF2-regulated antioxidant genes NQO1, SOD3 and OGG1 that are involved in protection against oxidative DNA damage was increased in Res- and Res + E2-treated mammary tissues. Resveratrol also prevented E2-mediated inhibition of detoxification genes AOX1 and FMO1. Inhibition of E2-mediated alterations in NRF2 promoter methylation and expression of NRF2 targeting miR-93 after Res treatment indicated Res-mediated epigenetic regulation of NRF2 during E2-induced breast carcinogenesis. Resveratrol treatment also induced apoptosis and inhibited E2-mediated increase in DNA damage in mammary tissues. Increased apoptosis and decreased DNA damage, cell migration, colony and mammosphere formation in Res- and Res + E2-treated MCF-10A cells suggested a protective role of Res against E2-induced mammary carcinogenesis. Small-interfering RNA-mediated silencing of NRF2 inhibited Res-mediated preventive effects on the colony and mammosphere formation. Taken together, these results suggest that Res inhibits E2-induced breast carcinogenesis via induction of NRF2-mediated protective pathways. PMID:24894866

  15. Development of a Career Student Guide for the Tech Prep Program for Henry County High School.

    ERIC Educational Resources Information Center

    Winchester, Ruth Ann

    This practicum report describes the research conducted in preparation for developing a career student guide to acquaint students attending Henry County High School (HCHS) in McDonough, Georgia, with the school's new tech prep program. Chapters 1 and 2 contain background information about HCHS' tech prep program and a review of literature regarding…

  16. A Virginia Tech MFT Ethics Class Reflects on the Shootings at Virginia Tech

    ERIC Educational Resources Information Center

    Piercy, Fred; Banker, Jamie; Traylor, Ryan; Krug, Sarah; Castanos, Carolina; Cole, Elise; Ciafardini, Anthony J.; Jordal, Christian; Rodgers, Brandon; Stewart, Shelley; Goodwin, Annabelle

    2008-01-01

    The authors of this article include the professor and most of the students in a doctoral course on marriage and family therapy ethical and professional issues that met the semester that a disturbed student shot and killed 32 Virginia Tech students and faculty before killing himself. In this article, we reflect through short essays on issues…

  17. Iowa High School High Tech: Promoting Careers in Technology for Students with Disabilities. Final Report and Implementation Manual.

    ERIC Educational Resources Information Center

    McQuillen, Terry; Nietupski, John; Berg, Deana Duncan; Daugherty, Vicki; Bildstein, Stephanie

    This final report and implementation manual describes the activities and outcomes of Iowa's High School High Tech (HSHT) program, a joint effort of Grant Wood Area Education Agency and Goodwill Industries of Southeast Iowa to inspire students with disabilities to pursue high tech careers. The program provides opportunities for students to learn…

  18. The Tech Prep Handbook: Essential Documents To Promte Effective Tech Prep Policies and Practices.

    ERIC Educational Resources Information Center

    Hensley, Oliver D., Ed.; And Others

    Developed during a project to document and analyze the tech prep initiative in Texas, this handbook contains exemplary documents associated with the model programs in the state. This second edition of the handbook organizes documents in sections (sections A, C, D, and G) that correspond to the major impact sectors identified during the research…

  19. Peace at Virginia Tech; A LEAP to Promote the Liberal Arts

    ERIC Educational Resources Information Center

    Wilson, Robin; Wasley, Paula

    2008-01-01

    This article reports that a Virginia Tech professor whose wife was among 32 people killed by a student gunman last year will become director of the university's new Center for Peace Studies and Violence Prevention. Jerzy Nowak will give up his job as chairman of Tech's horticulture department to take the new post on July 1. His wife, Jocelyne…

  20. Proceedings of the International Conferences on Education Technologies (ICEduTech) and Sustainability, Technology and Education (STE) (New Tapei City, Taiwan, December 10-12, 2014)

    ERIC Educational Resources Information Center

    Kommers, Piet, Ed.; Issa, Tomayess, Ed.; Issa, Theodora, Ed.; Chang, Dian-Fu, Ed.; Isias, Pedro, Ed.

    2014-01-01

    These proceedings contain the papers of the International Conferences on Educational Technologies (ICEduTech 2014), and Sustainability, Technology and Education (STE 2014). The International Conference on Educational Technologies (ICEduTech 2014) is the scientific conference addressing the real topics as seen by teachers, students, parents and…

  1. Integrated Technical Curriculum. Curriculum Developed for Project Second Chance II: Tech Reading, Tech Science, Tech Math, Automotive.

    ERIC Educational Resources Information Center

    Sorensen, Mary K.; And Others

    This integrated technical curriculum is designed to enroll and retain adult high school noncompleters in occupational programs by providing them with the remedial and content-area reading instruction needed for success in an automotive program. The following topics are covered in the four units: (1) skills for reading technical materials (basics…

  2. Soft Toys as Instructional Technology in Higher Education: The Case of Llewelyn the Lynx

    ERIC Educational Resources Information Center

    Raye, Lee

    2017-01-01

    Scholarship on instructive technologies in higher education has emphasized the use of high-tech facilitative technologies for long-term use, and low-tech props to illustrate single topics. This paper, on the contrary, discusses the use of a long-term, low-tech instructional technology: Llewelyn the Lynx was a soft animal used to assist with…

  3. Virginia Tech Was Slow to Respond to Gunman, Panel Finds

    ERIC Educational Resources Information Center

    Fischer, Karin; Wilson, Robin

    2007-01-01

    This article reports on the findings of the state panel on the Virginia Tech massacre. A state panel that investigated last spring's massacre at Virginia Tech has issued a harshly worded report that says the university erred in the way it handled a mentally disabled student who became a killer and in how it dealt with the immediate aftermath of…

  4. 78 FR 23622 - In the Matter of NewTech Brake Corp., Order of Suspension of Trading

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-19

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] In the Matter of NewTech Brake Corp., Order of Suspension of Trading April 17, 2013. It appears to the Securities and Exchange Commission that there is a lack of current and accurate information concerning the securities of NewTech Brake Corp. because it...

  5. Technology Predictors of Inquiry-Based Teaching: An Examination of Two K-12 1:1 Pilots

    ERIC Educational Resources Information Center

    Theis, Jennifer Lee

    2016-01-01

    The purpose of this study was to examine the relationship of technology use and facilitation of inquiry-based teaching across the curriculum through the implementation of a one-to-one technology pilot. This study also explored which technology related factors (Teacher Tech Use, Student Tech Use, Tech Barriers, Teacher Comfort) best predict the use…

  6. ECO TECH LINK: PT3 Grant Builds Technology Circles in the K-18 Community.

    ERIC Educational Resources Information Center

    Klinger, Katie; Duckett, Jane; Medrano, Maria; Crow, Nedra; Stowers, Gwen

    Through the vehicle of the PT3 grant program, ECO TECH LINK has built a strong consortium to support technology circles of government, education and business in order to raise student achievement scores, shorten the time it takes to earn a teaching credential, and enhance the quality of teacher credential courses. The ECO TECH LINK grant enables…

  7. Cumulative index to NASA Tech Briefs, 1986-1990, volumes 10-14

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Tech Briefs are short announcements of new technology derived from the R&D activities of the National Aeronautics and Space Administration. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This cumulative index of Tech Briefs contains abstracts and four indexes (subject, personal author, originating center, and Tech Brief number) and covers the period 1986 to 1990. The abstract section is organized by the following subject categories: electronic components and circuits, electronic systems, physical sciences, materials, computer programs, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  8. Manipulating presence influences the magnitude of virtual reality analgesia.

    PubMed

    Hoffman, Hunter G; Sharar, Sam R; Coda, Barbara; Everett, John J; Ciol, Marcia; Richards, Todd; Patterson, David R

    2004-09-01

    Excessive pain during medical procedures performed in unanesthetized patients is frequently reported, but can be reduced with virtual reality (VR) distraction. Increasing the person's illusion of going into the virtual world may increase how effectively VR distracts pain. Healthy volunteers aged 18-20 years participated in a double-blind between-groups design. Each subject received a brief baseline thermal pain stimulus, and the same stimulus again minutes later with either a Low Tech or a High Tech VR distraction. Each subject provided subjective 0-10 ratings of cognitive, sensory and affective components of pain, and rated their illusion of going inside the virtual world. Subjects in the High Tech VR group reported a stronger illusion of going into the virtual world (VR presence) than subjects in the Low Tech VR group, (4.2 vs. 2.5, respectively, P = 0.009) and more pain reduction (reduction of worst pain is 3.1 for High Tech VR vs. 0.7 for Low Tech VR, P < 0.001). Across groups, the amount of pain reduction was positively and significantly correlated with VR presence levels reported by subjects ( r = 0.48 for 'worst pain', P < 0.005).

  9. Effects of an 8-Week Outdoor Brisk Walking Program on Fatigue in Hi-Tech Industry Employees: A Randomized Control Trial.

    PubMed

    Wu, Li-Ling; Wang, Kuo-Ming; Liao, Po-I; Kao, Yu-Hsiu; Huang, Yi-Ching

    2015-10-01

    Over 73% of hi-tech industry employees in Taiwan lack regular exercise. They are exposed to a highly variable and stressful work environment for extended periods of time, and may subsequently experience depression, detrimental to workers' physiological and mental health. In this cross-sectional survey, the authors explored the effect of an 8-week brisk walking program on the fatigue of employees in the hi-tech industry. The participants, from a hi-tech company in northern Taiwan, were randomly assigned to an experimental group (EG; 41 subjects, Mage = 33.34 ± 6.40) or control group (CG; 45 subjects, Mage = 29.40 ± 3.60). Following the 8-week brisk walking program, the EG showed significantly lower scores for subjective fatigue, working motivation, attention, and overall fatigue. The authors confirmed that the 8-week outdoor brisk walking program significantly improved the level of fatigue among employees of the hi-tech industry. The finding serves as an important reference for health authorities in Taiwan and provides awareness of workplace health promotion in the hi-tech industry. © 2015 The Author(s).

  10. Supplemental progesterone and timing of resynchronization on pregnancy outcomes in lactating dairy cows.

    PubMed

    Bilby, T R; Bruno, R G S; Lager, K J; Chebel, R C; Moraes, J G N; Fricke, P M; Lopes, G; Giordano, J O; Santos, J E P; Lima, F S; Stevenson, J S; Pulley, S L

    2013-01-01

    The objective was to determine the effect of exogenous progesterone (P4) in a timed artificial insemination (TAI) protocol initiated at 2 different times post-AI on pregnancies per AI (P/AI) in lactating dairy cows. Cows (n=1,982) in 5 dairy herds were assigned randomly at a nonpregnancy diagnosis 32 ± 3 d post-AI to 1 of 4 resynchronization (RES) treatments arranged in a 2 × 2 factorial design using the Ovsynch-56 (GnRH, 7d later PGF2α, 56 h later GnRH, 16 h later TAI) protocol. Treatments were as follows: cows initiating RES 32 ± 3 d after AI with no supplemental P4 (d 32 RES-CON; n=516); same as d 32 RES-CON plus a controlled internal drug release (CIDR) insert containing P4 at the onset of Ovsynch-56 (d 32 RES-CIDR; n=503); cows initiating RES 39 ± 3 d after AI (d 39 RES-CON; n=494); and same as d 39 RES-CON plus a CIDR (d 39 RES-CIDR; n=491). Cows were inseminated if observed in estrus before TAI. The P/AI was determined 32 and 60 d after TAI. In a subgroup of cows (n=1,152), blood samples were collected and ovarian structures examined by ultrasonography on the days of the first GnRH (G1) and PGF2α of Ovsynch-56. Percentage of cows with a corpus luteum (CL) at G1 was unaffected by timing of treatments, but percentage of cows with a CL at PGF2α was greater for d 32 than for d 39 cows (87.9 vs. 79.4%). In addition, percentage of cows with P4 ≥ 1 ng/mL at G1 was unaffected by timing of treatments, but was increased for d 32 compared with d 39 RES cows on the day of the PGF2α of the RES protocols (86.5 vs. 74.3%). Treatment did not affect ovulation to G1 or P/AI 32 d after RES TAI (d 32 RES-CON=30.1%, d 32 RES-CIDR=28.8%, d 39 RES-CON=27.5%, d 39 RES-CIDR=30.5%). A greater percentage of d 39 RES cows underwent premature luteolysis during the RES protocol compared with d 32 RES cows. An interaction was detected between day of RES initiation and CIDR treatment, in which the CIDR increased P/AI 60 d after TAI for d 39 (CON=23.7% vs. CIDR=28.0%), but not for d 32 (CON=26.9% and CIDR=24.2%) cows. Pregnancy loss was unaffected by treatment. In addition, cows had improved P/AI 60 d after TAI when they received a CIDR and did not have a CL (CON-CL=28.2%, CON-No CL=19.2%, CIDR-CL=27.0%, and CIDR-No CL=26.5%) or had P4 <1 ng/mL (CON-High P4=27.8%, CON-Low P4=15.0%, CIDR-High P4=25.0%, and CIDR-Low P4=29.4%) at G1, but not if a CL was present or P4 was ≥ 1 ng/mL at G1. In conclusion, addition of a CIDR insert to supplement P4 during the RES protocol increased P/AI for cows initiating RES 39 ± 3 d after AI but not 32 ± 3 d after AI. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  11. Pulmonary Metabolism of Resveratrol: In Vitro and In Vivo Evidence

    PubMed Central

    Sharan, Satish

    2013-01-01

    The role of pulmonary metabolism in trans-resveratrol (RES) pharmacokinetics was studied in a mouse model. Plasma concentrations of RES and its major metabolites trans-resveratrol-3-sulfate (R3S) and trans-resveratrol-3-glucuronide (R3G) were compared after administration of RES by intravenous (IV) and intra-arterial (IA) routes. Total area under the curve (AUC) of RES decreased by approximately 50% when RES was administered by the IV route compared with the IA route. The AUC of R3G was also significantly higher in mice administered RES by the IV route compared with the IA route. In vitro studies performed with mouse and human lung fractions confirmed pulmonary metabolism of RES. Interestingly, mouse-lung fractions gave rise to both R3S and R3G, whereas human lung fractions yielded R3S. This indicates marked interspecies variation in RES conjugation, especially in the context of extrapolating rodent data to humans. Taken together, the results presented here underline, for the first time, the impact of pulmonary metabolism on resveratrol pharmacokinetics and interspecies differences in RES pulmonary metabolism. PMID:23474649

  12. Effects of an abbreviated obesity intervention supported by mobile technology: The ENGAGED randomized clinical trial.

    PubMed

    Spring, Bonnie; Pellegrini, Christine A; Pfammatter, Angela; Duncan, Jennifer M; Pictor, Alex; McFadden, H Gene; Siddique, Juned; Hedeker, Donald

    2017-07-01

    To determine the effects on weight loss of three abbreviated behavioral weight loss interventions with and without coaching and mobile technology. A randomized controlled efficacy study of three 6-month weight loss treatments was conducted in 96 adults with obesity: 1) self-guided (SELF), 2) standard (STND), or 3) technology-supported (TECH). STND and TECH received eight in-person group treatment sessions. SELF and STND used paper diaries to self-monitor diet, activity, and weight; TECH used a smartphone application with social networking features and wireless accelerometer. Weight loss was greater for TECH and STND than SELF at 6 months (-5.7 kg [95% confidence interval: -7.2 to -4.1] vs. -2.7 kg [95% confidence interval: -5.1 to -0.3], P < 0.05) but not 12 months. TECH and STND did not differ except that more STND (59%) than TECH (34%) achieved ≥ 5% weight loss at 6 months (P < 0.05). Self-monitoring adherence was greater in TECH than STND (P < 0.001), greater in both interventions than SELF (P < 0.001), and covaried with weight loss (r(84) = 0.36-0.51, P < 0.001). Abbreviated behavioral counseling can produce clinically meaningful weight loss regardless of whether self-monitoring is performed on paper or smartphone, but long-term superiority over standard of care self-guided treatment is challenging to maintain. © 2017 The Obesity Society.

  13. Anti-hepatocarcinoma effects of resveratrol nanoethosomes against human HepG2 cells

    NASA Astrophysics Data System (ADS)

    Meng, Xiang-Ping; Zhang, Zhen; Chen, Tong-sheng; Wang, Yi-fei; Wang, Zhi-ping

    2017-02-01

    Hepatocarcinoma, a malignant cancer, threaten human life badly. It is a current issue to seek the effective natural remedy from plant to treat cancer due to the resistance of the advanced hepatocarcinoma to chemotherapy. Resveratrol (Res) has been widely investigated with its strong anti-tumor activity. However, its low oral bioavailability restricts its wide application. In this study, we prepared resveratrol nanoethosomes (ResN) via ethanol injection method. The in vitro anti-hepatocarcinoma effects of ResN relative to efficacy of bulk Res were evaluated on proliferation and apoptosis of human HepG2 cells. ResN were spherical vesicles and its particle diameter, zeta potential were (115.8 +/- 1.3) nm and (-12.8 +/- 1.9) mV, respectively. ResN exhibited significant inhibitory effects against human HepG2 cells by MTT assay, and the IC50 value was 49.2 μg/ml (105.4 μg/ml of Res bulk solution). By flow cytometry assay, there was an increase in G2/M phase cells treated with ResN. The results demonstrated ResN could effectively block the G2/M phase of HepG2 cells, which can also enhance the inhibitory effect of Res against HepG2 cells.

  14. Psychological and Ethical Considerations Concerning the Debreather and Assisted Suicide: A Commentary on Ogden

    ERIC Educational Resources Information Center

    Kleespies, Phillip M.

    2010-01-01

    This article offers a commentary on the report by Russel Ogden (2010/this issue) on the use of the "debreather" for suicide assistance by the NuTech (or New Technologies for Self-Deliverance) program. The emergence of NuTech is set within its historical and political context. Nu Tech is criticized for its anarchic and extreme advocacy of…

  15. Project Georgia High School/High Tech

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Georgia High School/High Tech has been developing a suggested curriculum for use in its programs. The purpose of this instructional material is to provide a basic curriculum format for teachers of High School/High Tech students. The curriculum is designed to implement QCC classroom instruction that encourages career development in technological fields through post-secondary education, paid summer internships, and exposure to experiences in high technology.

  16. Development of an enzyme-linked immunoelectrotransfer blot (EITB) assay using two baculovirus expressed recombinant antigens for diagnosis of Taenia solium taeniasis.

    PubMed

    Levine, Min Z; Lewis, Melissa M; Rodriquez, Silvia; Jimenez, Juan A; Khan, Azra; Lin, Sehching; Garcia, Hector H; Gonzales, Armando E; Gilman, Robert H; Tsang, Victor C W

    2007-04-01

    Taeniasis diagnosis is an important step in the control and elimination of both cysticercosis and taeniasis. We report the development of 2 serological taeniasis diagnostic tests using recombinant antigens rES33 and rES38 expressed by baculovirus in insect cells in an EITB format. In laboratory testing with defined sera from nonendemic areas, rES33 has a sensitivity of 98% (n = 167) and a specificity of 99% (n = 310) (J index: 0.97); rES38 has a sensitivity of 99% (n = 146) and a specificity of 97% (n = 275) (J index: 0.96). Independent field testing in Peru showed 97% (n = 203) of the taeniasis sera were positive with rES33, and 100% of the nontaeniasis sera (n = 272) were negative with rES33; 98% (n = 198) of taeniasis sera were positive with rES38, and 91% (n = 274) of the nontaeniasis sera were negative with rES38. Among the Peruvian sera tested, 17 of 26 Peruvian Taenia saginata sera were false positive with rES38 test. Both tests were also examined with cysticercosis sera, with a positive rate ranging from 21% to 46%. rES33 and rES38 tests offer sensitive and specific diagnosis of taeniasis and easy sample collection through finger sticks that can be used in large-scale studies. They are currently being used in cysticercosis elimination programs in Peru.

  17. EDITORIAL: 'Best article' prize for the 5th anniversary of Environmental Research Letters 'Best article' prize for the 5th anniversary of Environmental Research Letters

    NASA Astrophysics Data System (ADS)

    Kammen, Dan; Wright, Guillaume

    2011-12-01

    To celebrate the 5th anniversary of Environmental Research Letters (ERL) the publishers of the journal, IOP Publishing, have awarded a prize for the five best articles published in ERL since the journal began in 2006. The procedure for deciding the winning articles was as thorough as possible to ensure that the most outstanding articles would win the prize. A shortlist of 25 nominated research articles, five for each year since ERL was launched, which were chosen based on a range of criteria including novelty, scientific impact, readership, broad appeal and wider media coverage, was selected. The ERL Editorial Board then assessed and rated these 25 articles in order to choose a winning article for each year. We would like to announce that the following articles have been awarded ERL's 5th anniversary best article prize: 2006/7 The Bodélé depression: a single spot in the Sahara that provides most of the mineral dust to the Amazon forest Ilan Koren, Yoram J Kaufman, Richard Washington, Martin C Todd, Yinon Rudich, J Vanderlei Martins and Daniel Rosenfeld 2006 Environ. Res. Lett. 1 014005 2008 Causes and impacts of the 2005 Amazon drought Ning Zeng, Jin-Ho Yoon, Jose A Marengo, Ajit Subramaniam, Carlos A Nobre, Annarita Mariotti and J David Neelin 2008 Environ. Res. Lett. 3 014002 2009 How difficult is it to recover from dangerous levels of global warming? J A Lowe, C Huntingford, S C B Raper, C D Jones, S K Liddicoat and L K Gohar 2009 Environ. Res. Lett. 4 014012 2010 Is physical water scarcity a new phenomenon? Global assessment of water shortage over the last two millennia Matti Kummu, Philip J Ward, Hans de Moel and Olli Varis 2010 Environ. Res. Lett. 5 034006 2011 Implications of urban structure on carbon consumption in metropolitan areas Jukka Heinonen and Seppo Junnila 2011 Environ. Res. Lett. 6 014018 Our congratulations go to these authors. In recognition of their outstanding work, we are delighted to offer all of the authors of the winning articles free publication in the journal until the end of 2012. Of course all of the shortlisted papers were of great merit, and the full list of nominees can be found below (in alphabetical order). Nominees Achard F, DeFries R, Eva H, Hansen M, Mayaux P and Stibig H-J 2007 Environ. Res. Lett. 2 045022 Baccini A, Laporte N, Goetz S J, Sun M and Dong H 2008 Environ. Res. Lett. 3 045011 Barona E, Ramankutty N, Hyman G and Coomes O T 2010 Environ. Res. Lett. 5 024002 Charpentier A D, Bergerson J A and MacLean H L 2009 Environ. Res. Lett. 4 014005 Chester M V and Horvath A 2009 Environ. Res. Lett. 4 024008 Cooley S R and Doney S C 2009 Environ. Res. Lett. 4 024007 Diffenbaugh N S, White M A, Jones G V and Ashfaq M 2011 Environ. Res. Lett. 6 024024 Farrell A E and Brandt A R 2006 Environ. Res. Lett. 1 014004 Graham W M, Condon R H, Carmichael R H, D'Ambra I, Patterson H K, Linn L J and Hernandez F J Jr 2010 Environ. Res. Lett. 5 045301 Hansen J E 2007 Environ. Res. Lett. 2 024002 Heinonen J and Junnila S 2011 Environ. Res. Lett. 6 014018 Jackson R B et al 2008 Environ. Res. Lett. 3 044006 Jiang M, Michael Griffin W, Hendrickson C, Jaramillo P, VanBriesen J and Venkatesh A 2011 Environ. Res. Lett. 6 034014 Koren I, Kaufman Y J, Washington R, Todd M C, Rudich Y, Martins J V and Rosenfeld D 2006 Environ. Res. Lett. 1 014005 Kummu M, Ward P J, de Moel H and Varis O 2010 Environ. Res. Lett. 5 034006 Lau W K M, Kim M-K, Kim K-M and Lee W-S 2010 Environ. Res. Lett. 5 025204 Lindeboom H J et al 2011 Environ. Res. Lett. 6 035101 Lowe J A, Huntingford C, Raper S C B, Jones C D, Liddicoat S K and Gohar L K 2009 Environ. Res. Lett. 4 014012 Möhler O, Benz S, Saathoff H, Schnaiter M, Wagner R, Schneider J, Walter S, Ebert V and Wagner S 2008 Environ. Res. Lett. 3 025007 Menon S, Akbari H, Mahanama S, Sednev I and Levinson R 2010 Environ. Res. Lett. 5 014005 Schneider A, Friedl M A and Potere D 2009 Environ. Res. Lett. 4 044003 Sloan T and Wolfendale A W 2008 Environ. Res. Lett. 3 024001 Tedesco M, Fettweis X, van den Broeke M R, van de Wal R S W, Smeets C J P P, van de Berg W J, Serreze M C and Box J E 2011 Environ. Res. Lett. 6 014005 Wang M, Wu M and Huo H 2007 Environ. Res. Lett. 2 024001 Zeng N, Yoon J H, Marengo J A, Subramaniam A, Nobre C A, Mariotti A and Neelin J D 2008 Environ. Res. Lett. 3 014002

  18. Regional Emphysema Score Predicting Overall Survival, Quality of Life and Pulmonary Function Recovery in Early-stage Lung Cancer Patients

    PubMed Central

    Dai, Jie; Liu, Ming; Swensen, Stephen J.; Stoddard, Shawn M.; Wampfler, Jason A.; Limper, Andrew H.; Jiang, Gening; Yang, Ping

    2017-01-01

    Introduction Pulmonary emphysema is a common comorbidity in lung cancer, but its role in tumor prognosis remains obscure. Our aim was to evaluate the impact of the regional emphysema score (RES) on patient’s overall survival, quality of life (QOL), and pulmonary function recovery in stage I–II lung cancer. Methods Between 1997 and 2009, 1,073 patients were identified and divided into two surgical groups (cancer in emphysematous [group 1, n=565] and non-emphysematous [group 2, n=435] region) and one non-surgical group (group 3, n=73). RES was derived from the emphysematous region and categorized into mild (≤5%), moderate (6–24%) and severe (25–60%). Results In group 1, patients with moderate and severe RES experienced slight decreases in postoperative FEV1, but increases in FEV1/FVC, compared to those with mild RES (p<0.01); however, this correlation was not observed in group 2. Post-treatment QOL was lower in patients with greater RES in all groups mainly due to dyspnea (p<0.05). Cox-regression analysis revealed that patients with higher RES had a significantly poorer survival in both surgical groups, with adjusted HRs of 1.41 and 1.43 for moderate RES and 1.63 and 2.04 for severe RES, respectively; however, this association was insignificant in the non-surgical group (adjusted HR of 0.99 for moderate/severe RES). Conclusions In surgically-treated patients with cancer in emphysematous region, RES is associated with postoperative changes in lung function. RES is also predictive of post-treatment QOL related to dyspnea in early-stage lung cancer. In both surgical groups, RES is an independent predictor of survival. PMID:28126539

  19. Factors and trade-offs with rehabilitation effectiveness and efficiency in newly disabled older persons.

    PubMed

    Chow, Patsy; Chen, Cynthia; Cheong, Angela; Fong, Ngan Phoon; Chan, Kin Ming; Tan, Boon Yeow; Menon, Edward; Ee, Chye Hua; Lee, Kok Keng; Koh, David; Koh, Gerald C

    2014-08-01

    To determine the factors for rehabilitation effectiveness (REs) and rehabilitation efficiency (REy) among newly disabled older persons and if there is any trade-off between REs and REy. Retrospective cohort study. Rehabilitation hospitals. Patients (N=8828) aged ≥65 years admitted for inpatient rehabilitation from 1996 to 2005. Not applicable. Independent factors affecting REs and REy were determined. The median rank ratios of REs to REy for each admission Barthel Index (BI) unit and number of days of stay were generated. The ideal ranges of admission BI score and length of stay (LOS) that corresponded to the REs to REy median rank ratio of 1 (both REs and REy optimized) were identified. Factors associated with poorer REs and REy were older age, Malay ethnicity, delayed admission, admission diagnosis of amputation, and comorbidities of dementia and stroke. An increase of 10 in admission BI score was associated with an increase of 3.47% in REs but a decrease of 1.1 per 30 days in REy; and an increase in LOS of 2.7 days was associated with an increase of 28% in REs but a decrease of 5.2 per 30 days in REy. A trade-off relation between REs and REy with respect to admission functional status and LOS was observed. The range, which optimized both REs and REy, was 50 to 59 units for admission BI score and 37 to 46 days for LOS. There are trade-offs between REs and REy with respect to admission functional status and LOS. Clinicians, policymakers, patients, and other stakeholders should be aware of such trade-offs when they make joint policy decisions about rehabilitation services. Copyright © 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  20. NASA Tech House: An early evaluation

    NASA Technical Reports Server (NTRS)

    1977-01-01

    An architect-engineering firm, as well as university participants, performed system studies, evaluated construction methods, performed cost effectiveness studies, and prepared construction drawings which incorporated the selected technology features into a final design. A Technology Utilization House (Tech House) based on this design was constructed at the NASA Langley Research Center in Hampton, Virginia. The Tech House is instrumented so that the performance of the design features and energy systems can be evaluated during a planned family live-in period. As such, the house is both a demonstration unit and a research laboratory. The Tech House is to demonstrate the kind of single-family residence that will probably be available within the next five years.

  1. Randomized clinical study assessing two membranes for guided bone regeneration of peri-implant bone defects: clinical and histological outcomes at 6 months.

    PubMed

    Naenni, Nadja; Schneider, David; Jung, Ronald E; Hüsler, Jürg; Hämmerle, Christoph H F; Thoma, Daniel S

    2017-10-01

    To test whether or not one of two membranes is superior for peri-implant-guided bone regeneration in terms of clinical and histologic outcomes. In 27 patients, 27 two-piece dental implants were placed in single-tooth gaps in the esthetic area. Buccal dehiscence and/or fenestration-type defects were regenerated using demineralized bovine bone mineral and randomly covered with either a resorbable membrane (RES) or a titanium-reinforced non-resorbable membrane (N-RES). Clinical measurements included vertical defect resolution and the horizontal thickness of regenerated bone at implant placement and at 6 months. Statistics were performed by means of nonparametric testing. The remaining mean vertical defect measured 4 mm (±2.07) (RES) and 2.36 mm (±2.09) (N-RES) (P = 0.044) at baseline and 0.77 mm (±0.85) (RES) and 0.21 mm (±0.80) (N-RES) (P = 0.021) at re-entry. This translated into a defect resolution of 85% (RES) and 90.7% (N-RES) (P = 0.10). The horizontal thickness after augmentation measured 3.46 mm (±0.52) (RES) and 2.82 mm (±0.50) (N-RES) (P = 0.004). The mean loss in horizontal thickness from baseline to re-entry measured 2.23 mm (SD ±1.21) (RES) and 0.14 mm (±0.79) (N-RES) (P = 0.017). The horizontal changes in thickness at the implant shoulder level were statistically significant between the groups (P = 0.0001). Both treatment modalities were clinically effective in regenerating bone as demonstrated by a similar horizontal thickness and vertical defect fill at 6 months. The N-RES group exhibited significantly less horizontal bone thickness reduction from baseline to follow-up. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Two Different Maintenance Strategies in the Hospital Environment: Preventive Maintenance for Older Technology Devices and Predictive Maintenance for Newer High-Tech Devices.

    PubMed

    Sezdi, Mana

    2016-01-01

    A maintenance program generated through the consideration of characteristics and failures of medical equipment is an important component of technology management. However, older technology devices and newer high-tech devices cannot be efficiently managed using the same strategies because of their different characteristics. This study aimed to generate a maintenance program comprising two different strategies to increase the efficiency of device management: preventive maintenance for older technology devices and predictive maintenance for newer high-tech devices. For preventive maintenance development, 589 older technology devices were subjected to performance verification and safety testing (PVST). For predictive maintenance development, the manufacturers' recommendations were used for 134 high-tech devices. These strategies were evaluated in terms of device reliability. This study recommends the use of two different maintenance strategies for old and new devices at hospitals in developing countries. Thus, older technology devices that applied only corrective maintenance will be included in maintenance like high-tech devices.

  3. Two Different Maintenance Strategies in the Hospital Environment: Preventive Maintenance for Older Technology Devices and Predictive Maintenance for Newer High-Tech Devices

    PubMed Central

    Sezdi, Mana

    2016-01-01

    A maintenance program generated through the consideration of characteristics and failures of medical equipment is an important component of technology management. However, older technology devices and newer high-tech devices cannot be efficiently managed using the same strategies because of their different characteristics. This study aimed to generate a maintenance program comprising two different strategies to increase the efficiency of device management: preventive maintenance for older technology devices and predictive maintenance for newer high-tech devices. For preventive maintenance development, 589 older technology devices were subjected to performance verification and safety testing (PVST). For predictive maintenance development, the manufacturers' recommendations were used for 134 high-tech devices. These strategies were evaluated in terms of device reliability. This study recommends the use of two different maintenance strategies for old and new devices at hospitals in developing countries. Thus, older technology devices that applied only corrective maintenance will be included in maintenance like high-tech devices. PMID:27195666

  4. Nalco Fuel Tech

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Michalak, S.

    1995-12-31

    The Nalco Fuel Tech with its seat at Naperville (near Chicago), Illinois, is an engineering company working in the field of technology and equipment for environmental protection. A major portion of NALCO products constitute chemical materials and additives used in environmental protection technologies (waste-water treatment plants, water treatment, fuel modifiers, etc.). Basing in part on the experience, laboratories and RD potential of the mother company, the Nalco Fuel Tech Company developed and implemented in the power industry a series of technologies aimed at the reduction of environment-polluting products of fuel combustion. The engineering solution of Nalco Fuel Tech belong tomore » a new generation of environmental protection techniques developed in the USA. They consist in actions focused on the sources of pollutants, i.e., in upgrading the combustion chambers of power engineering plants, e.g., boilers or communal and/or industrial waste combustion units. The Nalco Fuel Tech development and research group cooperates with leading US investigation and research institutes.« less

  5. Displacement in new economy labor markets: Post-displacement wage loss in high tech versus low tech cities.

    PubMed

    Davis, Daniel J; Rubin, Beth A

    2016-11-01

    While scholars and politicians tout education as the salve to employment disruptions, we argue that the geography of the new economy, and the social closure mechanisms that geography creates, may be just as important as individuals' characteristics for predicting post-displacement wage loss (or gain). We use data from the 2012 Displaced Workers ement of the Current Population Survey and from the 2010 United States Census to test hypotheses linking local labor markets in different industrial contexts to post-displacement wage loss. Our results point to age as a closure mechanism, and to the partially protective effect of education in high-tech versus low-tech economic sectors. This study is the first to use national level data to examine how employment in high-tech cities influences post-displacement wages. These findings are relevant both for theorizing about the new economy and for public policy. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. LanzaTech- Capturing Carbon. Fueling Growth.

    ScienceCinema

    NONE

    2018-01-16

    LanzaTech will design a gas fermentation system that will significantly improve the rate at which methane gas is delivered to a biocatalyst. Current gas fermentation processes are not cost effective compared to other gas-to-liquid technologies because they are too slow for large-scale production. If successful, LanzaTech's system will process large amounts of methane at a high rate, reducing the energy inputs and costs associated with methane conversion.

  7. High-Tech, Low-Tech, No-Tech: Communications Strategies During Blackouts

    DTIC Science & Technology

    2013-12-01

    share radiation measurements; it was created within a week of the Fukushima nuclear disaster . More than 3.5 million data readings have already been...national nuclear crisis, especially as the extent of the disaster at the Fukushima Daiichi plant became known. This is where hyper-local communication...accompany major crises, particularly natural disasters such as severe weather events. Thus, during crises, communications are often severely hampered

  8. Defense AT&L (Volume 34, Number 4, July-August 2005)

    DTIC Science & Technology

    2005-08-01

    government, industry, and academic communities. The system provides a single site where individuals and organizations can quickly access and search...made specifically about Navy TechMatch, the design, human interface, and system operation of DoD TechMatch are identical . Anyone can view, sort, and...causes another that subsequently supports the first]. Industry, academic , and DoD partners will benefit from the TechMatch concept. Tailored information

  9. NASA Tech House

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The NASA Technology Utilization House, called Tech House, was designed and constructed at NASA's Langley Research Center in Hampton, Virginia, to demonstrate new technology that is available or will be available in the next several years and how the application of aerospace technology could help advance the homebuilding industry. Solar energy use, energy and water conservation, safety, security, and cost were major considerations in adapting the aerospace technology to the construction of Tech House.

  10. High School/High Tech Program Guide: An Implementation Guide for High School/High Tech Program Coordinators. Promoting Careers in Science and Technology for High School Students with Disabilities.

    ERIC Educational Resources Information Center

    Office of Disability Employment Policy (DOL), Washington, DC.

    This implementation guide is intended to assist educators in planning, establishing, building, and managing a High School/High Tech project for high school students with disabilities. The program is designed to develop career opportunities, provide activities that will spark an interest in high technology fields, and encourage students to pursue…

  11. Implementation of DoD ManTech Projects Receiving FY03-05 Funds

    DTIC Science & Technology

    2008-12-01

    ManTech project is providing an integrated tool to grind, laser clad , and finish repair work of submarine VLS tubes. The system is scheduled for...hours from about 400 - 500 hours to 40 - 50 hours resulting in improved readiness. The in- situ laser clad process eliminates the use of hazardous...Alternate Remote Shipboard Lighting for Reduced Costs .......................................................... 14 2.2.10 ManTech for Military Lasers

  12. Comparing Safari Tech Books Online and Books24x7 E-Book Collections: A Case Study from the University of British Columbia Library

    ERIC Educational Resources Information Center

    Barsky, Eugene; Schattman, Lisa; Greenwood, Aleteia

    2009-01-01

    Most academic libraries are seeking to provide electronic access to the very dynamic and changing field of technology related material. "Safari Tech Books Online" and "Books24x7" are the major e-book collections in this area. We compared the "Safari Tech Books Online" and "Books24x7" e-book packages as to…

  13. Does the Number of College Credits Earned in a Tech Prep and Postsecondary Enrollment Options Program Predict College Success?

    ERIC Educational Resources Information Center

    Meyer, Bruce A.

    2011-01-01

    The purpose of this study was to examine a Tech Prep Program located in Northwest Ohio and determine the degree to which college credits earned in high school through the Tech Prep and PSEO Programs predict college success and if there were any significant gender/race differences in credits earned and college success as well as high school…

  14. A Virginia Tech MFT ethics class reflects on the shootings at Virginia Tech.

    PubMed

    Piercy, Fred; Banker, Jamie; Traylor, Ryan; Krug, Sarah; Castanos, Carolina; Cole, Elise; Ciafardini, Anthony J; Jordal, Christian; Rodgers, Brandon; Stewart, Shelley; Goodwin, Annabelle

    2008-04-01

    The authors of this article include the professor and most of the students in a doctoral course on marriage and family therapy ethical and professional issues that met the semester that a disturbed student shot and killed 32 Virginia Tech students and faculty before killing himself. In this article, we reflect through short essays on issues related to the tragedy, ethics, and recovery.

  15. Engineering English and the High-Tech Industry: A Case Study of an English Needs Analysis of Process Integration Engineers at a Semiconductor Manufacturing Company in Taiwan

    ERIC Educational Resources Information Center

    Spence, Paul; Liu, Gi-Zen

    2013-01-01

    The global high-tech industry is characterized by extreme competitiveness, innovation, and widespread use of English. Consequently, Taiwanese high-tech companies require engineers that are talented in both their engineering and English abilities. In response to the lack of knowledge regarding the English skills needed by engineers in Taiwan's…

  16. An Implementation Analysis of Threat Assessment Policies in Public Universities and Community Colleges in Central Texas: A Post Virginia Tech Incident Assessment

    ERIC Educational Resources Information Center

    Piet DeLaTorre, Christine

    2011-01-01

    It is clear that the tragic events at Virginia Tech and other institutions of higher education (IHEs) have brought threat assessment to the forefront of higher education literature and increased public concern for campus safety. IHEs have a profound duty to learn from the Virginia Tech tragedy and to recognize their responsibility in providing a…

  17. A systematic quality review of high-tech AAC interventions as an evidence-based practice.

    PubMed

    Morin, Kristi L; Ganz, Jennifer B; Gregori, Emily V; Foster, Margaret J; Gerow, Stephanie L; Genç-Tosun, Derya; Hong, Ee Rea

    2018-06-01

    Although high-tech augmentative and alternative communication (AAC) is commonly used to teach social-communication skills to people with autism spectrum disorder or intellectual disabilities who have complex communication needs, there is a critical need to evaluate the efficacy of this approach. The aim of this systematic review was to evaluate the quality of single-case experimental design research on the use of high-tech AAC to teach social-communication skills to individuals with autism spectrum disorder or intellectual disabilities who have complex communication needs, to determine if this intervention approach meets the criteria for evidence-based practices as outlined by the What Works Clearinghouse. Additionally, information on the following extended methodological standards is reported on all included studies: participant description, description of setting and materials, interventionist description, baseline and intervention description, maintenance, generalization, procedural integrity, and social validity. The results from 18 multiple-baseline or multiple-probe experiments across 17 studies indicate that using high-tech AAC to teach social-communication skills to individuals with autism spectrum disorder or intellectual disabilities and complex communication needs can be considered an evidence-based practice, although the review of comparison (i.e., alternating treatment) design studies did not indicate that high-tech AAC is significantly better than low-tech AAC.

  18. Georgia Institute of Technology chilled water system evaluation and master plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-05-15

    As the host of the Olympic Village for the 1996 Atlanta Olympics, Georgia Tech has experienced a surge in construction activities over the last three years. Over 1.3 million square feet of new buildings have been constructed on the Georgia Tech campus. This growth has placed a strain on the Georgia Tech community and challenged the facilities support staff charged with planning and organizing utility services. In concert with Olympic construction, utility planners have worked to ensure long term benefits for Georgia Tech facilities while meeting the short term requirements of the Olympic Games. The concentration of building construction inmore » the northwest quadrant of the campus allowed planners to construct a satellite chilled water plant to serve the needs of this area and provide the opportunity to integrate this section of the campus with the main campus chilled water system. This assessment and master plan, funded in part by the US Department of Energy, has evaluated the chilled water infrastructure at Georgia Tech, identified ongoing problems and made recommendations for long term chilled water infrastructure development and efficiency improvements. The Georgia Tech office of Facilities and RDA Engineering, Inc. have worked together to assemble relevant information and prepare the recommendations contained in this document.« less

  19. Self-Nanoemulsifying Drug Delivery System for Resveratrol: Enhanced Oral Bioavailability and Reduced Physical Fatigue in Rats

    PubMed Central

    Yen, Ching-Chi; Hsu, Mei-Chich; Wu, Yu-Tse

    2017-01-01

    Resveratrol (RES), a natural polyphenolic compound, exerts anti-fatigue activity, but its administration is complicated by its low water solubility. To improve RES bioavailability, this study developed a self-nanoemulsifying drug delivery system (SNEDDS) for RES and evaluated its anti-fatigue activity and rat exercise performance by measuring fatigue-related parameters, namely lactate, ammonia, plasma creatinine phosphokinase, and glucose levels and the swimming time to exhaustion. Through solubility and emulsification testing, the optimized SNEDDS composed of Capryol 90, Cremophor EL, and Tween 20 was developed; the average particle size in this formulation, which had favorable self-emulsification ability, was approximately 41.3 ± 4.1 nm. Pharmacokinetic studies revealed that the oral bioavailability of the optimized RES-SNEDDS increased by 3.2-fold compared with that of the unformulated RES-solution. Pretreatment using the RES-SNEDDS before exercise accelerated the recovery of lactate after exercise; compared with the vehicle group, the plasma ammonia level in the RES-SNEDDS group significantly decreased by 65.4%, whereas the glucose level significantly increased by approximately 1.8-fold. Moreover, the swimming time to exhaustion increased by 2.1- and 1.8-fold, respectively, compared with the vehicle and RES-solution pretreatment groups. Therefore, the developed RES-SNEDDS not only enhances the oral bioavailability of RES but may also exert anti-fatigue pharmacological effect. PMID:28841149

  20. Resveratrol and its combination with α-tocopherol mediate salt adaptation in citrus seedlings.

    PubMed

    Kostopoulou, Zacharoula; Therios, Ioannis; Molassiotis, Athanassios

    2014-05-01

    Resveratrol, a phytoalexin found in red wine, has the potential to impact a variety of human diseases but its function in plants exposed to stressful conditions is still unknown. In the present study the effect of exogenous application of resveratrol (Res), α-tocopherol (α-Toc) and their combination (Res+α-Toc) in salt adaptation of citrus seedlings was investigated. It was found that Res, α-Toc or Res+α-Toc treatments reduced NaCl-derived membrane permeability (EL), lipid peroxidation (MDA) and pigments degradation, whereas companied Res and α-Toc application also reduced H2O2 accumulation in leaves and restored the reduction of photosynthesis induced by NaCl. Application of Res under salinity retained Cl- in roots while Res+α-Toc reduced the translocation of Na+ and Cl- to leaves. Carbohydrates and proline, phenols, total ascorbic acid and glutathione were remarkably affected by NaCl as well as by chemical treatments in leaves and roots of citrus. NaCl treatment increased the activity of superoxide dismutase (SOD), ascorbate peroxidase (APX), peroxidase (POD), glutathione reductase (GR), polyphenol oxidase (PPO) in leaves while SOD and POD activities were decreased in roots by this treatment. Also, Res, α-Toc or Res+α-Toc treatments displayed tissue specific activation or deactivation of the antioxidant enzymes. Overall, this work revealed a new functional role of Res in plants and provided evidence that the interplay of between Res and α-Toc is involved in salinity adaptation. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  1. Tech House

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The members of the Swain family- Dr. Charles "Bill" Swain, wife Elaine, daughter Carol, 17, son "Chuck", 12, and dog Susie have an interesting assignment. They are active participants in an important NASA research program involving the application of space-age technology to home construction. b' Transplanted Floridians, the Swains now reside in NASA's Tech House, loatedat Langley Research Center, Hampton, Virginia. Their job is to use and help evaluate the variety of advanced technology systems in Tech House. A contemporary three-bedroom home, Tech House incorporates NASA technology, the latest commercial building techniques and other innovations, all designed to reduce energy and water consumption and to provide new levels of comfort, convenience, security and fire safety. Tech House equipment performed well in initial tests, but a house is not a home until it has people. That's where the Swains come in. NASA wants to see how the various systems work under actual living conditions, to confirm the effectiveness of the innovations or to determine necessary modifications for improvement. The Swains are occupying the house for a year, during which NASA engineers are computer monitoring the equipment and assembling a record of day-to-day performance. . Tech House is a laboratory rather than a mass production prototype, but its many benefits may influence home design and construction. In a period of sharply rising utility costs, widespread adoption of Tech House features could provide large-scale savings to homeowners and potentially enormous national benefit in resources conservation. Most innovations are aerospace spinoffs: Some of the equipment is now commercially available; other systems are expected to be in production within a few years. Around 1980, a Tech House-type of home could be built for $45-50,000 (1 976 dollars). It is estimated that the homeowner would save well over $20,000 (again 1976 dollars) in utility costs over the average mortgage span of 20 years.

  2. Biomass burning smoke episodes in Finland from Eastern European wildfires

    NASA Astrophysics Data System (ADS)

    Leino, Katri E.; Riuttanen, Laura; Nieminen, Tuomo; Dal Maso, Miikka; Väänänen, Riikka; Pohja, Toivo; Keronen, Petri; Järvi, Leena; Aalto, Pasi P.; Virkkula, Aki; Kerminen, Veli-Matti; Petäjä, Tuukka; Kulmala, Markku

    2014-05-01

    Biomass burning emissions from Eastern Europe are occasionally observed in Finland. In spring of 2006 and the late summers of 2006 and 2010, smoke plumes were transported to large parts of Finland. By combining multiple methods we were able to study the horizontal and vertical properties of long-range transported smoke plume, as well as time evolution of particle number size distributions in an aged biomass burning smoke. In this study we used trace gas and aerosol particle number size distribution measurements at three SMEAR stations (Station for Measuring Forest Ecosystem - Atmosphere Relations; Ruuskanen et al., 2003; Hari & Kulmala, 2005; Järvi et al., 2009). Vertical distribution of the smoke was studied by a small aircraft, Cessna FR172F, instrumented with Ultrafine Condensation Particle Counter and CO2/H2O -gas analyser. The airborne measurements were compared with vertical profiles from a polarization-sensitive, two-wavelength lidar (CALIOP; the Cloud-Aerosol Lidar with Orthogonal Polarization; Winker et al., 2009) onboard the CALIPSO satellite (the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation). HYSPLIT 4 (Hybrid Single Particle Lagrangian Integrated Trajectory Model; Draxler, 1999) backward trajectories as well as MODIS (Moderate Resolution Imaging Spectroradiometer) Terra thermal anomalies data (MOD14A1) were used together with synoptic analyses to study the transport and the horizontal distribution of the smoke. In the spring 2006, there was a blocking high pressure system in Eastern Europe and smoke from the Eastern European fires was transported far to the north-west. The smoke episode in Finland lasted for two weeks. In summers of 2006 and 2010 the smoke came to Finland in a warm sector of a low-pressure system and the episodes lasted for less than two days. Smoke plumes had elevated concentrations of aerosol particles, black carbon and CO, and varying concentrations of CO2, SO2, O3 and NOx. The difference to the background air was clear. At least one of the smoke plumes had a layered structure, and the smoke plumes were observed to be vertically and horizontally inhomogeneous. Aerosol number size distributions peaked at 100-200 nm size, median particle size being 60-250 % larger than in July-August on average. Growth of aerosol particles in the aged smoke plume was observed. References: Draxler R. R. (1999). HYSPLIT4 user's guide. NOAA Tech. Memo. ERL ARL-230. Hari P. & Kulmala M. (2005). Boreal Environ. Res. 10, 315-322. Järvi L. et al. (2009). Boreal Environ. Res. 14, 86-109. Ruuskanen T. M. et al. (2003). Boreal. Environ. Res., 8, 335-349. Winker D. M. et al. (2009). J. Atmos. Oceanic Technol., 26, 2310-2323.

  3. Sell, Sell, Sell or Learn, Learn, Learn? The EdTech Market in New Zealand's Education System--Privatisation by Stealth?

    ERIC Educational Resources Information Center

    Wright, Noeline; Peters, Michael

    2017-01-01

    An article in "The Atlantic" "Quantifying the Ed-Tech Market" (2015), which draws on a review by the Education Technology Industry Network, reports that the U.S. Ed-tech market totalled $8.38 billion in the 2012-2013 academic year, which is up from $7.9 billion the year before, and up 11.7 per cent from 2009. K-12 online course…

  4. Tech-Prep/Associate Degree Program Guide: Tech Prep Associate Degree Program, Business Administration Associate Degree Program, Office Administration Associate Degree Program, Allied Health Associate Degree Program.

    ERIC Educational Resources Information Center

    Marmaras, Judy; Neri, Pat

    The Tech-Prep Associate Degree Program (TPAD) at the Community College of Rhode Island (CCRI) in Warwick, is a high school/community college partnership providing high school students with an alternative program of study focused on goal setting, basic academic skills development, and the skills needed to pursue a career in a technical, business or…

  5. Inactivation of Microbiological Contaminants in Drinking Water by Ultraviolet Light Technology: NeoTech Aqua Solutions, Inc.; Ultraviolet Water Treatment System, NeoTech D438™ (Report and VS)

    EPA Science Inventory

    The NeoTech Aqua Solutions, Inc. D438™ UV Water Treatment System was tested to validate the UV dose delivered by the system using biodosimetry and a set line approach. The set line for 40 mJ/cm2 measured Reduction Equivalent Dose (RED) was based on validation testing at three (3)...

  6. Economic Migrants in a Global Labour Market: A Report on the Recruitment and Retention of Asian Computer Professionals by Canadian High Tech Firms. CPRN Discussion Paper.

    ERIC Educational Resources Information Center

    Rao, Badrinath

    The recruitment and retention of Asian computer professionals by Canadian high-tech companies was examined by interviewing 8 Canadian-born information technology (IT) workers, 47 Asian-born IT workers, and 8 human resource (HR) professionals employed by high-tech companies in Ottawa. Of the 47 Asians, 33 stated that they did not know much about…

  7. The Effects of Partnership Management on Supply Chain Cooperative Performance: A Case Study of High-Tech Industry

    NASA Astrophysics Data System (ADS)

    Wu, Mei-Ying; Chang, Yun-Ju; Weng, Yung-Chien

    2009-08-01

    With the structural change of global supply chains, the relationship between manufacturers and suppliers has transformed into a long-term partnership. Thus, this study aims to explore the partnership between manufacturers and suppliers in Taiwan's high-tech industry. Four constructs, including partner characteristic, partnership quality, partnership closeness, and cooperative performance, induced from previous literatures are used to construct the research framework and hypotheses. A questionnaire survey is then performed on executives and staffs involved in the high-tech industry. The proposed framework and hypotheses are empirically validated through confirmatory factory analysis and structural equation modeling. It is expected that the research findings can serve as a reference for Taiwan's high-tech industry on building partnerships.

  8. Cardiovascular Small Heat Shock Protein HSPB7 Is a Kinetically Privileged Reactive Electrophilic Species (RES) Sensor.

    PubMed

    Surya, Sanjna L; Long, Marcus J C; Urul, Daniel A; Zhao, Yi; Mercer, Emily J; EIsaid, Islam M; Evans, Todd; Aye, Yimon

    2018-02-08

    Small heat shock protein (sHSP)-B7 (HSPB7) is a muscle-specific member of the non-ATP-dependent sHSPs. The precise role of HSPB7 is enigmatic. Here, we disclose that zebrafish Hspb7 is a kinetically privileged sensor that is able to react rapidly with native reactive electrophilic species (RES), when only substoichiometric amounts of RES are available in proximity to Hspb7 expressed in living cells. Among the two Hspb7-cysteines, this RES sensing is fulfilled by a single cysteine (C117). Purification and characterizations in vitro reveal that the rate for RES adduction is among the most efficient reported for protein-cysteines with native carbonyl-based RES. Covalent-ligand binding is accompanied by structural changes (increase in β-sheet-content), based on circular dichroism analysis. Among the two cysteines, only C117 is conserved across vertebrates; we show that the human ortholog is also capable of RES sensing in cells. Furthermore, a cancer-relevant missense mutation reduces this RES-sensing property. This evolutionarily conserved cysteine-biosensor may play a redox-regulatory role in cardioprotection.

  9. New Fks hot spot for acquired echinocandin resistance in Saccharomyces cerevisiae and its contribution to intrinsic resistance of Scedosporium species.

    PubMed

    Johnson, Michael E; Katiyar, Santosh K; Edlind, Thomas D

    2011-08-01

    Echinocandins represent a new antifungal group with potent activity against Candida species. These lipopeptides inhibit the synthesis of β-1,3-glucan, the major cell wall polysaccharide. Acquired resistance or reduced echinocandin susceptibility (RES) is rare and associated with mutations in two "hot spot" regions of Fks1 or Fks2, the probable β-1,3-glucan synthases. In contrast, many fungi demonstrate intrinsic RES for reasons that remain unclear. We are using Saccharomyces cerevisiae to understand the basis for RES by modeling echinocandin-Fks interaction. Previously characterized mutations confer cross-RES; we screened for mutations conferring differential RES, implying direct interaction of that Fks residue with a variable echinocandin side chain. One mutant (in an fks1Δ background) exhibited ≥16-fold micafungin and anidulafungin versus caspofungin RES. Sequencing identified a novel Fks2 mutation, W714L/Y715N. Equivalent W695L/Y696N and related W695L/F/C mutations in Fks1 generated by site-directed mutagenesis and the isolation of a W695L-equivalent mutation in Candida glabrata confirmed the role of the new "hot spot 3" in RES. Further mutagenesis expanded hot spot 3 to Fks1 residues 690 to 700, yielding phenotypes ranging from cross-RES to differential hypersusceptibility. Fks1 sequences from intrinsically RES Scedosporium species revealed W695F-equivalent substitutions; Fks1 hybrids expressing Scedosporium prolificans hot spot 3 confirmed that this substitution imparts RES.

  10. Research Center Renaming Will Honor Senator Domenici

    NASA Astrophysics Data System (ADS)

    2008-05-01

    New Mexico Tech and the National Radio Astronomy Observatory (NRAO) will rename the observatory's research center on the New Mexico Tech campus to honor retiring U.S. Senator Pete V. Domenici in a ceremony on May 30. The building that serves as the scientific, technical, and administrative center for the Very Large Array (VLA) and Very Long Baseline Array (VLBA) radio telescopes will be named the "Pete V. Domenici Science Operations Center." The building previously was known simply as the "Array Operations Center." Sen. Pete V. Domenici Sen. Pete V. Domenici "The new name recognizes the strong and effective support for science that has been a hallmark of Senator Domenici's long career in public service," said Dr. Fred Lo, NRAO Director. New Mexico Tech President Daniel H. Lopez said Sen. Domenici has always been a supporter of science and research in Socorro and throughout the state. "He's been a statesman for New Mexico, the nation -- and without exaggeration -- for the world," Lopez said. "Anyone with that track record deserves this recognition." Van Romero, Tech vice president of research and economic development, has served as the university's main lobbyist in Washington, D.C., for more than a decade. He said Sen. Domenici has always been receptive to new ideas and willing to take risks. "Over the years, Sen. Domenici has always had time to listen to our needs and goals," Romero said. "He has served as a champion of New Mexico Tech's causes and we owe him a debt of gratitude for all his efforts over the decades." Originally dedicated in 1988, the center houses offices and laboratories that support VLA and VLBA operations. The center also supports work on the VLA modernization project and on the international Atacama Large Millimeter/submillimeter Array (ALMA) project. Work on ALMA at the Socorro center and at the ALMA Test Facility at the VLA site west of Socorro has focused on developing and testing equipment to be deployed at the ALMA site in Chile's Atacama Desert. The research facility, part of the National Science Foundation-funded NRAO, was located on the NM Tech campus through a joint Federal-State effort spearheaded by Domenici. "Senator Domenici has worked hard over the years to support research both at New Mexico Tech and at the NRAO, and our facility on the New Mexico Tech campus is a symbol of that support. It's highly appropriate to name it after him," said Dr. Ethan Schreier, President of Associated Universities Inc., which operates the NRAO for the National Science Foundation. Senator Domenici helped make New Mexico Tech's Magdalena Ridge Observatory (MRO) a reality and provided essential support for NRAO's VLA and VLBA. MRO is one of the world's most technologically-advanced optical observatories. The VLA is the most scientifically-productive ground-based telescope in the history of astronomy. "Both these facilities will advance the frontiers of 21st-Century astrophysics, and keep our state and its research community in the forefront of science worldwide," said Dr. Robert Dickman, NRAO's Director for New Mexico Operations. Domenici also was instrumental in bringing the International Law Enforcement Academy -- another New Mexico Tech division -- to Roswell. During the Reagan Administration, Domenici sponsored the legislation that allowed the university to use the "M" Mountain range for research and testing. Lopez said the U.S. Department of the Interior would not let the university conduct testing on the range. A high level bureaucrat told Laurence Lattman, then the president of Tech, that it "would take an act of Congress" for Tech to have unlimited access to the land. Domenici sponsored the legislation -- signed by Reagan -- that gave Tech access to the land. Over the years, Domenici's support has helped Tech launch the homeland security training program in Playas, the EarthScope research and other anti-terrorism training programs. "All these projects benefit New Mexico Tech," Lopez said. "But these programs also benefit the nation. Senator Domenici has always been careful to make sure that federal money went to programs that benefit the entire nation." The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.

  11. Impact of water table level on annual carbon and greenhouse gas balances of a restored peat extraction area

    NASA Astrophysics Data System (ADS)

    Järveoja, J.; Peichl, M.; Maddison, M.; Soosaar, K.; Vellak, K.; Karofeld, E.; Teemusk, A.; Mander, Ü.

    2015-10-01

    Peatland restoration may provide a potential after-use option to mitigate the negative climate impact of abandoned peat extraction areas; currently, however, knowledge about restoration effects on the annual balances of carbon (C) and greenhouse gas (GHG) exchanges is still limited. The aim of this study was to investigate the impact of contrasting water table levels (WTL) on the annual C and GHG balances of restoration treatments with high (Res-H) and low (Res-L) WTL relative to an unrestored bare peat (BP) site. Measurements of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) fluxes were conducted over a full year using the closed chamber method and complemented by measurements of abiotic controls and vegetation cover. Three years following restoration, the difference in the mean WTL resulted in higher bryophyte and lower vascular plant cover in Res-H relative to Res-L. Consequently, greater gross primary production and autotrophic respiration associated with greater vascular plant cover were observed in Res-L compared to Res-H. However, the means of the measured net ecosystem CO2 exchanges (NEE) were not significantly different between Res-H and Res-L. Similarly, no significant differences were observed in the respective means of CH4 and N2O exchanges in Res-H and Res-L, respectively. In comparison to the two restored sites, greater net CO2, similar CH4 and greater N2O emissions occurred in BP. On the annual scale, Res-H, Res-L and BP were C sources of 111, 103 and 268 g C m-2 yr-1 and had positive GHG balances of 4.1, 3.8 and 10.2 t CO2 eq ha-1 yr-1, respectively. Thus, the different WTLs had a limited impact on the C and GHG balances in the two restored treatments three years following restoration. However, the C and GHG balances in Res-H and Res-L were considerably lower than in BP owing to the large reduction in CO2 emissions. This study therefore suggests that restoration may serve as an effective method to mitigate the negative climate impacts of abandoned peat extraction areas.

  12. Hi-Res scan mode in clinical MDCT systems: Experimental assessment of spatial resolution performance

    PubMed Central

    Cruz-Bastida, Juan P.; Gomez-Cardona, Daniel; Li, Ke; Sun, Heyi; Hsieh, Jiang; Szczykutowicz, Timothy P.; Chen, Guang-Hong

    2016-01-01

    Purpose: The introduction of a High-Resolution (Hi-Res) scan mode and another associated option that combines Hi-Res mode with the so-called High Definition (HD) reconstruction kernels (referred to as a Hi-Res/HD mode in this paper) in some multi-detector CT (MDCT) systems offers new opportunities to increase spatial resolution for some clinical applications that demand high spatial resolution. The purpose of this work was to quantify the in-plane spatial resolution along both the radial direction and tangential direction for the Hi-Res and Hi-Res/HD scan modes at different off-center positions. Methods: A technique was introduced and validated to address the signal saturation problem encountered in the attempt to quantify spatial resolution for the Hi-Res and Hi-Res/HD scan modes. Using the proposed method, the modulation transfer functions (MTFs) of a 64-slice MDCT system (Discovery CT750 HD, GE Healthcare) equipped with both Hi-Res and Hi-Res/HD modes were measured using a metal bead at nine different off-centered positions (0–16 cm with a step size of 2 cm); at each position, both conventional scans and Hi-Res scans were performed. For each type of scan and position, 80 repeated acquisitions were performed to reduce noise induced uncertainties in the MTF measurements. A total of 15 reconstruction kernels, including eight conventional kernels and seven HD kernels, were used to reconstruct CT images of the bead. An ex vivo animal study consisting of a bone fracture model was performed to corroborate the MTF results, as the detection of this high-contrast and high frequency task is predominantly determined by spatial resolution. Images of this animal model generated by different scan modes and reconstruction kernels were qualitatively compared with the MTF results. Results: At the centered position, the use of Hi-Res mode resulted in a slight improvement in the MTF; each HD kernel generated higher spatial resolution than its counterpart conventional kernel. However, the MTF along the tangential direction of the scan field of view (SFOV) was significantly degraded at off-centered positions, yet the combined Hi-Res/HD mode reduced this azimuthal MTF degradation. Images of the animal bone fracture model confirmed the improved spatial resolution at the off-centered positions through the use of the Hi-Res mode and HD kernels. Conclusions: The Hi-Res/HD scan improve spatial resolution of MDCT systems at both centered and off-centered positions. PMID:27147351

  13. Hi-Res scan mode in clinical MDCT systems: Experimental assessment of spatial resolution performance.

    PubMed

    Cruz-Bastida, Juan P; Gomez-Cardona, Daniel; Li, Ke; Sun, Heyi; Hsieh, Jiang; Szczykutowicz, Timothy P; Chen, Guang-Hong

    2016-05-01

    The introduction of a High-Resolution (Hi-Res) scan mode and another associated option that combines Hi-Res mode with the so-called High Definition (HD) reconstruction kernels (referred to as a Hi-Res/HD mode in this paper) in some multi-detector CT (MDCT) systems offers new opportunities to increase spatial resolution for some clinical applications that demand high spatial resolution. The purpose of this work was to quantify the in-plane spatial resolution along both the radial direction and tangential direction for the Hi-Res and Hi-Res/HD scan modes at different off-center positions. A technique was introduced and validated to address the signal saturation problem encountered in the attempt to quantify spatial resolution for the Hi-Res and Hi-Res/HD scan modes. Using the proposed method, the modulation transfer functions (MTFs) of a 64-slice MDCT system (Discovery CT750 HD, GE Healthcare) equipped with both Hi-Res and Hi-Res/HD modes were measured using a metal bead at nine different off-centered positions (0-16 cm with a step size of 2 cm); at each position, both conventional scans and Hi-Res scans were performed. For each type of scan and position, 80 repeated acquisitions were performed to reduce noise induced uncertainties in the MTF measurements. A total of 15 reconstruction kernels, including eight conventional kernels and seven HD kernels, were used to reconstruct CT images of the bead. An ex vivo animal study consisting of a bone fracture model was performed to corroborate the MTF results, as the detection of this high-contrast and high frequency task is predominantly determined by spatial resolution. Images of this animal model generated by different scan modes and reconstruction kernels were qualitatively compared with the MTF results. At the centered position, the use of Hi-Res mode resulted in a slight improvement in the MTF; each HD kernel generated higher spatial resolution than its counterpart conventional kernel. However, the MTF along the tangential direction of the scan field of view (SFOV) was significantly degraded at off-centered positions, yet the combined Hi-Res/HD mode reduced this azimuthal MTF degradation. Images of the animal bone fracture model confirmed the improved spatial resolution at the off-centered positions through the use of the Hi-Res mode and HD kernels. The Hi-Res/HD scan improve spatial resolution of MDCT systems at both centered and off-centered positions.

  14. Cumulative Index to NASA Tech Briefs

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Tech Briefs are short announcements of new technology derived from the R&D activities of the National Aeronautics and Space Administration. This Index to NASA Tech Briefs lists the technological innovations derived from the U.S. space program and published during the period January through December 1968. A new five year cycle of cumulative indexes begins with this index. The main section is arranged in six categories: Electrical (Electronic); Physical Sciences (Energy Sources); Materials (Chemistry); Life Sciences; Mechanical; and Computer Programs.

  15. Tech Forum Highlights: Last October, Technology Directors, Superintendents, Principals, Teacher Trainers, and Other Education Leaders Gathered Just outside New York City for T&L's One-Day Tech Forum Event

    ERIC Educational Resources Information Center

    McLester, Susan

    2005-01-01

    This brief article describes the events and discussions that took place at the annual Fall Tech Forum event, hosted at the IBM Conference Center in Palisades, New York. At the Forum, practitioners and leaders gathered for a day of professional development sessions and networking with colleagues and industry experts. The highlights of the Forum are…

  16. EcoCAR Challenge Profile: Virginia Tech

    ScienceCinema

    Gantt, Lynn

    2017-12-27

    Since childhood, Lynn Gantt has had a deep seeded passion for cars and the mechanics that drive them. The Virginia native spent his weekends rebuilding antique tractors with his dad to race at tractor pulls across the state, and now the Virginia Tech graduate student is the proud team co-leader of Virginia Tech's EcoCAR Challenge team -- the winners of the three-year long competition, as announced last night at an awards ceremony in Washington, D.C.

  17. LASER Tech Briefs, February 1995. Volume 3, No. 1

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Topics included in this issue of LASER Tech Briefs are: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Mechanics, Fabrication, and Mathematics and Information Sciences, and

  18. Develop applications based on android: Teacher Engagement Control of Health (TECH)

    NASA Astrophysics Data System (ADS)

    Sasmoko; Manalu, S. R.; Widhoyoko, S. A.; Indrianti, Y.; Suparto

    2018-03-01

    Physical and psychological condition of teachers is very important because it helped determine the realization of a positive school climate and productive so that they can run their profession optimally. This research is an advanced research on the design of ITEI application that able to see the profile of teacher’s engagement in Indonesia and to optimize the condition is needed an application that can detect the health of teachers both physically and psychologically. The research method used is the neuroresearch method combined with the development of IT system design for TECH which includes server design, database and android TECH application display. The study yielded 1) mental health benchmarks, 2) physical health benchmarks, and 3) the design of Android Application for Teacher Engagement Control of Health (TECH).

  19. New Fks Hot Spot for Acquired Echinocandin Resistance in Saccharomyces cerevisiae and Its Contribution to Intrinsic Resistance of Scedosporium Species▿

    PubMed Central

    Johnson, Michael E.; Katiyar, Santosh K.; Edlind, Thomas D.

    2011-01-01

    Echinocandins represent a new antifungal group with potent activity against Candida species. These lipopeptides inhibit the synthesis of β-1,3-glucan, the major cell wall polysaccharide. Acquired resistance or reduced echinocandin susceptibility (RES) is rare and associated with mutations in two “hot spot” regions of Fks1 or Fks2, the probable β-1,3-glucan synthases. In contrast, many fungi demonstrate intrinsic RES for reasons that remain unclear. We are using Saccharomyces cerevisiae to understand the basis for RES by modeling echinocandin-Fks interaction. Previously characterized mutations confer cross-RES; we screened for mutations conferring differential RES, implying direct interaction of that Fks residue with a variable echinocandin side chain. One mutant (in an fks1Δ background) exhibited ≥16-fold micafungin and anidulafungin versus caspofungin RES. Sequencing identified a novel Fks2 mutation, W714L/Y715N. Equivalent W695L/Y696N and related W695L/F/C mutations in Fks1 generated by site-directed mutagenesis and the isolation of a W695L-equivalent mutation in Candida glabrata confirmed the role of the new “hot spot 3” in RES. Further mutagenesis expanded hot spot 3 to Fks1 residues 690 to 700, yielding phenotypes ranging from cross-RES to differential hypersusceptibility. Fks1 sequences from intrinsically RES Scedosporium species revealed W695F-equivalent substitutions; Fks1 hybrids expressing Scedosporium prolificans hot spot 3 confirmed that this substitution imparts RES. PMID:21576441

  20. The protective effects of resveratrol on Schwann cells with toxicity induced by ethanol in vitro.

    PubMed

    Yuan, Hongtu; Zhang, Jingfen; Liu, Huaxiang; Li, Zhenzhong

    2013-09-01

    Schwann cells (SCs) are the myelin forming cells in the peripheral nervous system, they play a key role in the pathology of various polyneuropathies and provide trophic support to axons via expression of various neurotrophic factors, such as nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF). Ethanol (EtOH) adversely affected both SCs proliferation and myelin formation in culture. Resveratrol (Res) has been shown to regulate many cellular processes and to display multiple protective and therapeutic effects. Whether Res has protective effects on SCs with EtOH-induced toxicity is still unclear. The protective efficacy of Res on EtOH-treated SCs in vitro was investigated in the present study. Res improved cell viability of the EtOH-treated SCs. Hoechst 33342 staining and terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuridine triphosphate nick-end labeling analysis showed that the EtOH-induced apoptosis was inhibited by Res. The effects of Res were blocked by the 5'-adenosine monophosphate-activated protein kinase inhibitor Compound C and the silencing information regulator T1 inhibitor nicotinamide. Res could increase the mRNA and protein levels of BDNF and GDNF in the EtOH-treated SCs. However, the EtOH-induced increase of NGF in the SCs is inhibited by Res. The data from the present study indicate that Res protects SCs from EtOH-induced cell death and regulates the expression of neurotrophicfactors. Res and its derivative may be effective for the treatment of neuropathic diseases induced by EtOH. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Dimethyl Sulfoxide Attenuates Acute Lung Injury Induced by Hemorrhagic Shock/Resuscitation in Rats.

    PubMed

    Tsung, Yu-Chi; Chung, Chih-Yang; Wan, Hung-Chieh; Chang, Ya-Ying; Shih, Ping-Cheng; Hsu, Han-Shui; Kao, Ming-Chang; Huang, Chun-Jen

    2017-04-01

    Inflammation following hemorrhagic shock/resuscitation (HS/RES) induces acute lung injury (ALI). Dimethyl sulfoxide (DMSO) possesses anti-inflammatory and antioxidative capacities. We sought to clarify whether DMSO could attenuate ALI induced by HS/RES. Male Sprague-Dawley rats were allocated to receive either a sham operation, sham plus DMSO, HS/RES, or HS/RES plus DMSO, and these were denoted as the Sham, Sham + DMSO, HS/RES, or HS/RES + DMSO group, respectively (n = 12 in each group). HS/RES was achieved by drawing blood to lower mean arterial pressure (40-45 mmHg for 60 min) followed by reinfusion with shed blood/saline mixtures. All rats received an intravenous injection of normal saline or DMSO immediately before resuscitation or at matching points relative to the sham groups. Arterial blood gas and histological assays (including histopathology, neutrophil infiltration, and lung water content) confirmed that HS/RES induced ALI. Significant increases in pulmonary expression of tumor necrosis factor-α (TNF-α), malondialdehyde, nuclear factor-kappa B (NF-κB), inducible nitric oxide synthase (iNOS), and cyclooxygenase 2 (COX-2) confirmed that HS/RES induced pulmonary inflammation and oxidative stress. DMSO significantly attenuated the pulmonary inflammation and ALI induced by HS/RES. The mechanisms for this may involve reducing inflammation and oxidative stress through inhibition of pulmonary NF-κB, TNF-α, iNOS, and COX-2 expression.

  2. Resveratrol stimulates mitochondrial fusion by a mechanism requiring mitofusin-2.

    PubMed

    Robb, Ellen L; Moradi, Fereshteh; Maddalena, Lucas A; Valente, Andrew J F; Fonseca, Joao; Stuart, Jeffrey A

    2017-04-01

    Resveratrol (RES) is a plant-derived stilbene associated with a wide range of health benefits. Mitochondria are a key downstream target of RES, and in some cell types RES promotes mitochondrial biogenesis, altered cellular redox status, and a shift toward oxidative metabolism. Mitochondria exist as a dynamic network that continually remodels via fusion and fission processes, and the extent of fusion is related to cellular redox status and metabolism. We investigated RES's effects on mitochondrial network morphology in several cell lines using a quantitative approach to measure the extent of network fusion. 48 h continuous treatment with 10-20 μM RES stimulated mitochondrial fusion in C2C12 myoblasts, PC3 cancer cells, and mouse embryonic fibroblasts stimulated significant increases in fusion in all instances, resulting in larger and more highly branched mitochondrial networks. Mitofusin-2 (Mfn2) is a key protein facilitating mitochondrial fusion, and its expression was also stimulated by RES. Using Mfn2-null cells we demonstrated that RES's effects on mitochondrial fusion, cellular respiration rates, and cell growth are all dependent upon the presence of Mfn2. Taken together, these results demonstrate that Mfn2 and mitochondrial fusion are affected by RES in ways that appear to relate to RES's known effects on cellular metabolism and growth. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Zoledronate and ion-releasing resins impair dentin collagen degradation.

    PubMed

    Tezvergil-Mutluay, A; Seseogullari-Dirihan, R; Feitosa, V P; Tay, F R; Watson, T F; Pashley, D H; Sauro, S

    2014-10-01

    This study analyzed the amounts of solubilized telopeptides cross-linked carboxyterminal telopeptide of type I collagen (ICTP) and C-terminal crosslinked telopeptide of type I collagen (CTX) derived from matrix-metalloproteinases (MMPs) and cysteine cathepsins (CTPs) subsequent to application of a filler-free (Res.A) or an ion-releasing resin (Res.B) to ethylenediaminetetraacetic acid (EDTA)-demineralized dentin with or without zoledronate-containing primer (Zol-primer) pre-treatment. The chemical modification induced following treatments and artificial saliva (AS) storage was also analyzed through attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Totally EDTA-demineralized specimens were infiltrated with Res.A or Res.B with or without Zol-primer pre-treatment, light-cured, and immersed in AS for up to 4 wk. ICTP release was reduced following infiltration with Res.B and further reduced when Res.B was used with Zol-primer; remarkable phosphate mineral uptake was attained after AS storage. CTX release was increased in Res.A- and Res.B-treated dentin. However, when Zol-primer was used with Res.A, the CTX release fell significantly compared to the other tested resin-infiltration methods. In conclusion, zoledronate offers an additional inhibitory effect to the ion-releasing resins in MMP-mediated collagen degradation. However, Zol-primer induces a modest reduction in CTX release only when used with resin-based systems containing no ion-releasing fillers. © International & American Associations for Dental Research.

  4. Zoledronate and Ion-releasing Resins Impair Dentin Collagen Degradation

    PubMed Central

    Tezvergil-Mutluay, A.; Seseogullari-Dirihan, R.; Feitosa, V.P.; Tay, F.R.; Watson, T.F.; Pashley, D.H.; Sauro, S.

    2014-01-01

    This study analyzed the amounts of solubilized telopeptides cross-linked carboxyterminal telopeptide of type I collagen (ICTP) and C-terminal crosslinked telopeptide of type I collagen (CTX) derived from matrix-metalloproteinases (MMPs) and cysteine cathepsins (CTPs) subsequent to application of a filler-free (Res.A) or an ion-releasing resin (Res.B) to ethylenediaminetetraacetic acid (EDTA)-demineralized dentin with or without zoledronate-containing primer (Zol-primer) pre-treatment. The chemical modification induced following treatments and artificial saliva (AS) storage was also analyzed through attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Totally EDTA-demineralized specimens were infiltrated with Res.A or Res.B with or without Zol-primer pre-treatment, light-cured, and immersed in AS for up to 4 wk. ICTP release was reduced following infiltration with Res.B and further reduced when Res.B was used with Zol-primer; remarkable phosphate mineral uptake was attained after AS storage. CTX release was increased in Res.A- and Res.B-treated dentin. However, when Zol-primer was used with Res.A, the CTX release fell significantly compared to the other tested resin-infiltration methods. In conclusion, zoledronate offers an additional inhibitory effect to the ion-releasing resins in MMP-mediated collagen degradation. However, Zol-primer induces a modest reduction in CTX release only when used with resin-based systems containing no ion-releasing fillers. PMID:25074494

  5. Protective effects of resveratrol and its analogs on age-related macular degeneration in vitro.

    PubMed

    Kang, Jung-Hwan; Choung, Se-Young

    2016-12-01

    Damage of retinal pigment epithelial (RPE) cells by A2E may be critical for age-related macular degeneration (AMD) management. Accumulation and photooxidation of A2E are known to be one of the critical causes in AMD. Here, we evaluated the protective effect of resveratrol (RES), piceatannol (PIC) and RES glycones on blue-light-induced RPE cell death caused by A2E photooxidation. A2E treatment followed by blue light exposure caused significant damages on human RPE cells (ARPE-19). But the damages were attenuated by post- and pre-treatment of RES and PIC in our in vitro models. The results of cell free system and FAB-MS analysis clearly showed that the reduction of A2E by blue light exposure was significantly rescued, and that oxidized forms of A2E were significantly reduced by RES or PIC treatment. Besides, RES or PIC inhibited the intracellular accumulation of A2E. Not only RES and PIC but RES glycones showed protection of ARPE-19 cells against A2E and blue-light-induced photo-damage. These findings demonstrate that RES and its analogs may have protective effects against A2E and blue-light-induced ARPE-19 cell death through regulation of A2E accumulation as well as photooxidation of A2E. Thus RES and its analogs may be beneficial for AMD treatment.

  6. Hydrogen-induced structural transition in single layer ReS2

    NASA Astrophysics Data System (ADS)

    Yagmurcukardes, M.; Bacaksiz, C.; Senger, R. T.; Sahin, H.

    2017-09-01

    By performing density functional theory-based calculations, we investigate how structural, electronic and mechanical properties of single layer ReS2 can be tuned upon hydrogenation of its surfaces. It is found that a stable, fully hydrogenated structure can be obtained by formation of strong S-H bonds. The optimized atomic structure of ReS2H2 is considerably different than that of the monolayer ReS2 which has a distorted-1T phase. By performing phonon dispersion calculations, we also predict that the Re2-dimerized 1T structure (called 1T {{}\\text{R{{\\text{e}}2}}} ) of the ReS2H2 is dynamically stable. Unlike the bare ReS2 the 1T {{}\\text{R{{\\text{e}}2}}} -ReS2H2 structure which is formed by breaking the Re4 clusters into separated Re2 dimers, is an indirect-gap semiconductor. Furthermore, mechanical properties of the 1T {{}\\text{R{{\\text{e}}2}}} phase in terms of elastic constants, in-plane stiffness (C) and Poisson ratio (ν) are investigated. It is found that full hydrogenation not only enhances the flexibility of the single layer ReS2 crystal but also increases anisotropy of the elastic constants.

  7. NASA Tech Briefs, August 1998. Volume 22, No. 8

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage of medical design, electronic components and circuits, electronic systems, software, materials, mechanics, machinery/automation, physical sciences, and a special section of Photonics Tech Briefs.

  8. NASA Tech Briefs, July 2001. Volume 25, No. 7

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage sections on Data Acquisition, and sections on electronic components and systems, software, mechanics, machinery/automation, biomedical and a special section of Photonics Tech Briefs.

  9. 34 CFR 406.4 - What regulations apply?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.4 What regulations apply? The following regulations apply to the State-Administered Tech-Prep Education Program: (a) The...

  10. Chemical Vapor Deposition Growth of Degenerate p-Type Mo-Doped ReS2 Films and Their Homojunction.

    PubMed

    Qin, Jing-Kai; Shao, Wen-Zhu; Xu, Cheng-Yan; Li, Yang; Ren, Dan-Dan; Song, Xiao-Guo; Zhen, Liang

    2017-05-10

    Substitutional doping of transition metal dichalcogenide two-dimensional materials has proven to be effective in tuning their intrinsic properties, such as band gap, transport characteristics, and magnetism. In this study, we realized substitutional doping of monolayer rhenium disulfide (ReS 2 ) with Mo via chemical vapor deposition. Scanning transmission electron microscopy demonstrated that Mo atoms are successfully doped into ReS 2 by substitutionally replacing Re atoms in the lattice. Electrical measurements revealed the degenerate p-type semiconductor behavior of Mo-doped ReS 2 field effect transistors, in agreement with density functional theory calculations. The p-n diode device based on a doped ReS 2 and ReS 2 homojunction exhibited gate-tunable current rectification behaviors, and the maximum rectification ratio could reach up to 150 at V d = -2/+2 V. The successful synthesis of p-type ReS 2 in this study could largely promote its application in novel electronic and optoelectronic devices.

  11. Mastery of Content Representation (CoRes) Related TPACK High School Biology Teacher

    NASA Astrophysics Data System (ADS)

    Nasution, W. R.; Sriyati, S.; Riandi, R.; Safitri, M.

    2017-09-01

    The purpose of this study was to determine the mastery of Content Representation (CoRes) teachers related to the integration of technology and pedagogy in teaching Biology (TPACK). This research uses a descriptive method. The data were taken using instruments CoRes as the primary data and semi-structured interviews as supporting data. The subjects were biology teacher in class X MIA from four schools in Bandung. Teachers raised CoRes was analyzed using a scoring rubric CoRes with coding 1-3 then categorized into a group of upper, middle, or lower. The results showed that the two teachers in the lower category. This results means that the control of teachers in defining the essential concept in the CoRes has not been detailed and specific. Meanwhile, two other teachers were in the middle category. This means that the ability of teachers to determine the essential concepts in the CoRes are still inadequate so that still needs to be improved.

  12. Tomorrow’s Handgun: Ensuring the Right Gun for All Military Law Enforcement Officers

    DTIC Science & Technology

    2016-02-01

    www.military.com/equipment/m9-pistol. 23 Ibid. 24 Russell, Sara M. Soldier Perspectives on Small Arms in Combat. Tech. no. CRM D0015259.A2. Alexandria...pistol-of- choice-1749620057. Russell, Sara M. Soldier Perspectives on Small Arms in Combat. Tech. no. CRM D0015259.A2. Alexandria, VA: CNA...Tech. no. CRM D0015259.A2. Alexandria, VA: CNA, 2006. Print. "The Avalon Project: Laws of War - Declaration on the Use of Bullets Which Expand or

  13. Index to 1982 NASA Tech Briefs, volume 7, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1982 Tech Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  14. Cumulative Index to NASA Tech Briefs 1963-1969

    NASA Technical Reports Server (NTRS)

    1970-01-01

    Tech Briefs are short announcements of new technology derived from the research and development activities of the National Aeronautics and Space Administration. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This Cumulative index to NASA Tech Briefs lists those published from 1963 through 1969. The main listing is divided into six categokies: Electrical (Electronic), Physical Sciences (Energy Sources), Materials (Chemistry), Life Sciences, Mechanical, and Computer Programs.

  15. Index to 1984 NASA Tech Briefs, volume 9, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1984 Tech B Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  16. Index to 1981 NASA Tech Briefs, volume 6, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1981 Tech Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  17. The Evolution and Impact of PCS Technology.

    DTIC Science & Technology

    1994-09-01

    CTIA), June, 1994), p. 4. 44 Communication Daily, Vol. 14, No. 137, July 18, 1994, p.3. i45 FinTech Mobile Communications, June 16, 1994. 46 FCC...a palm-sized portable answering machine 3 which can receive and replay voice messages based on Voice Now service being developed I 47 FinTech Mobile...1994. 66 FinTech Mobile Communications, June 16, 1994. 67 Leslie Cauley, "U S West Inc., AirTouch Plan," Wall Street Journal, July 26, 1994. I II-10

  18. Index to 1983 NASA Tech Briefs, volume 8, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1983 Tech Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  19. Index to 1985 NASA Tech Briefs, volume 10, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1985 Tech Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  20. Historical and Archeological Investigations of Fort Bisland and Lower Bayou Teche, St. Mary Parish, Louisiana

    DTIC Science & Technology

    1991-06-01

    marsh deposits and sediments originating from the adjacent Lafourche delta complex. Relative sea level within the project region continues to rise...unique natural levee complex that consists of as many as three natural levees flanking both sides of Bayou Teche. From the center of Bayou Teche outward...loam, silty clay, and clay. These deposits are over 8 m thick beneath the center of the outer natural levee. These sediments interfinger and pinch out

  1. Problems and Countermeasures of Zhejiang High-Tech Enterprises Industry-University-Institute Cooperation in China

    NASA Astrophysics Data System (ADS)

    Zhou, Qing; Mao, Chong-Feng; Hou, Lin

    Industry-university-institute cooperation is an important means to accelerate technical development and achievements for high-tech enterprises. Considering that Zhejiang high-tech enterprises existed some problems which included low cooperative level, single distribution, weak secondary R&D ability, obvious risk and so on, government should play an guiding role on improving information service system, enhancing cooperative level, promoting scientific intermediary service organization system construction, and building better environment for Industry-university-institute cooperation.

  2. Index to 1986 NASA Tech Briefs, volume 11, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Short announcements of new technology derived from the R&D activities of NASA are presented. These briefs emphasize information considered likely to be transferrable across industrial, regional, or disciplinary lines and are issued to encourage commercial application. This index for 1986 Tech Briefs contains abstracts and four indexes: subject, personal author, originating center, and Tech Brief Number. The following areas are covered: electronic components and circuits, electronic systems, physical sciences, materials, life sciences, mechanics, machinery, fabrication technology, and mathematics and information sciences.

  3. UNL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aptekar, Alexander

    The final report on New York City College of Technology (City Tech) DURA (Diverse | Urban | Resilient | Adaptable) home project. City Tech has participated in the Solar Decathlon 2015 project as DURA. The DURA team consists of students, faculty, volunteers, Service Corps participants, Industry advisers, recent graduates and others. The DURA team researched, designed, and constructed a zero energy prototype house. This process was a valuable opportunity for City Tech as a project of such scale has not been completed before with the integration of so many departments and their students.

  4. LASER Tech Briefs, Fall 1994. Volume 2, No. 4

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Topics in this issue of LASER Tech briefs include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Fabrication Technology, Mathematics and Information Sciences, and Life Sciences

  5. NASA Tech Briefs, August 2002. Volume 26, No. 8

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on computers, electronic components and systems, software, materials, mechanics, machinery/automation, manufacturing, physical sciences, information sciences, book and reports, and Motion control Tech Briefs.

  6. New generation extracorporeal membrane oxygenation with MedTech Mag-Lev, a single-use, magnetically levitated, centrifugal blood pump: preclinical evaluation in calves.

    PubMed

    Fujiwara, Tatsuki; Nagaoka, Eiki; Watanabe, Taiju; Miyagi, Naoto; Kitao, Takashi; Sakota, Daisuke; Mamiya, Taichi; Shinshi, Tadahiko; Arai, Hirokuni; Takatani, Setsuo

    2013-05-01

    We have evaluated the feasibility of a newly developed single-use, magnetically levitated centrifugal blood pump, MedTech Mag-Lev, in a 3-week extracorporeal membrane oxygenation (ECMO) study in calves against a Medtronic Bio-Pump BPX-80. A heparin- and silicone-coated polypropylene membrane oxygenator MERA NHP Excelung NSH-R was employed as an oxygenator. Six healthy male Holstein calves with body weights of about 100 kg were divided into two groups, four in the MedTech group and two in the Bio-Pump group. Under general anesthesia, the blood pump and oxygenator were inserted extracorporeally between the main pulmonary artery and the descending aorta via a fifth left thoracotomy. Postoperatively, both the pump and oxygen flow rates were controlled at 3 L/min. Heparin was continuously infused to maintain the activated clotting time at 200-240 s. All the MedTech ECMO calves completed the study duration. However, the Bio-Pump ECMO calves were terminated on postoperative days 7 and 10 because of severe hemolysis and thrombus formation. At the start of the MedTech ECMO, the pressure drop across the oxygenator was about 25 mm Hg with the pump operated at 2800 rpm and delivering 3 L/min flow. The PO2 of the oxygenator outlet was higher than 400 mm Hg with the PCO2 below 45 mm Hg. Hemolysis and thrombus were not seen in the MedTech ECMO circuits (plasma-free hemoglobin [PFH] < 5 mg/dL), while severe hemolysis (PFH > 20 mg/dL) and large thrombus were observed in the Bio-Pump ECMO circuits. Plasma leakage from the oxygenator did not occur in any ECMO circuits. Three-week cardiopulmonary support was performed successfully with the MedTech ECMO without circuit exchanges. The MedTech Mag-Lev could help extend the durability of ECMO circuits by the improved biocompatible performances. © 2013, Copyright the Authors. Artificial Organs © 2013, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  7. Impact of water table level on annual carbon and greenhouse gas balances of a restored peat extraction area

    NASA Astrophysics Data System (ADS)

    Järveoja, Järvi; Peichl, Matthias; Maddison, Martin; Soosaar, Kaido; Vellak, Kai; Karofeld, Edgar; Teemusk, Alar; Mander, Ülo

    2016-05-01

    Peatland restoration may provide a potential after-use option to mitigate the negative climate impact of abandoned peat extraction areas; currently, however, knowledge about restoration effects on the annual balances of carbon (C) and greenhouse gas (GHG) exchanges is still limited. The aim of this study was to investigate the impact of contrasting mean water table levels (WTLs) on the annual C and GHG balances of restoration treatments with high (ResH) and low (ResL) WTL relative to an unrestored bare peat (BP) site. Measurements of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) fluxes were conducted over a full year using the closed chamber method and complemented by measurements of abiotic controls and vegetation cover. Three years following restoration, the difference in the mean WTL resulted in higher bryophyte and lower vascular plant cover in ResH relative to ResL. Consequently, greater gross primary production and autotrophic respiration associated with greater vascular plant cover were observed in ResL compared to ResH. However, the means of the measured net ecosystem CO2 exchanges (NEE) were not significantly different between ResH and ResL. Similarly, no significant differences were observed in the respective means of CH4 and N2O exchanges. In comparison to the two restored sites, greater net CO2, similar CH4 and greater N2O emissions occurred in BP. On the annual scale, ResH, ResL and BP were C sources of 111, 103 and 268 g C m-2 yr-1 and had positive GHG balances of 4.1, 3.8 and 10.2 t CO2 eq ha-1 yr-1, respectively. Thus, the different WTLs had a limited impact on the C and GHG balances in the two restored treatments 3 years following restoration. However, the C and GHG balances in ResH and ResL were considerably lower than in BP due to the large reduction in CO2 emissions. This study therefore suggests that restoration may serve as an effective method to mitigate the negative climate impacts of abandoned peat extraction areas.

  8. Protective effects of resveratrol on postmenopausal osteoporosis: regulation of SIRT1-NF-κB signaling pathway.

    PubMed

    Feng, Jing; Liu, Shuai; Ma, Sai; Zhao, Jian; Zhang, Wei; Qi, Wei; Cao, Pengchong; Wang, Zheng; Lei, Wei

    2014-12-01

    Postmenopausal osteoporosis severely jeopardizes human health. Seeking for therapeutic drugs without side effects is of great necessity. Our study was designed to investigate whether resveratrol, an agonist of SIRT1, could have favorable effect on osteoporosis and to explore the underlying mechanisms. Rat osteoporosis model (ovariectomy group, OVX) was established by bilateral ovariectomy. Three different doses of resveratrol were used: 5 mg/kg/d (low-dosed, RES(LD)), 25 mg/kg/d (medium-dosed, RES(MD)), and 45 mg/kg/d (high-dosed, RES(HD)). Results showed that RES(LD) did not show any significant effect on OVX alterations, while RES(MD) and RES(HD) significantly elevated the decreased bone mineral density induced by osteoporosis (RES(MD) 0.205 ± 0.023, RES(HD) 0.214 ± 0.053 vs. OVX 0.165 ± 0.050 g/cm(2) respectively; P < 0.05). Serum markers alkaline phosphatase (ALP) and osteocalcin were moderately restored by resveratrol. Moreover, resveratrol improved bone structure in OVX rats, demonstrated by hematoxylin-eosin staining and micro-computed tomographic results. In vitro results revealed that resveratrol promoted osteoblast differentiation of bone marrow mesenchymal stromal cells, evidenced by the increase of ALP generation and mRNA expression of collagen 1 (P < 0.05; RES(MD), RES(HD) vs. control group). SIRT1 gene silencing by siRNA transfection blocked these beneficial effects of resveratrol (P < 0.05; RES + SIRT1(KD) vs. RES(HD)). Western blot results showed that resveratrol activated SIRT1 and subsequently suppressed the activity of NF-κB with decreased expression level of p-IκBα and NF-κB p65 (P < 0.05). Our findings verified the effects of specific dosed resveratrol on postmenopausal osteoporosis through osteoblast differentiation via SIRT1-NF-κB signaling pathway. This study suggested the therapeutic potential of resveratrol against osteoporosis and stressed the importance of effective doses. © The Author 2014. Published by ABBS Editorial Office in association with Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.

  9. Aphasia vs. Apraxia

    MedlinePlus

    ... tech system – Paper and pencil High-tech system – Computer program that produces voice output at keystroke Oral ... for Aphasia Actions Speak as Loud as Words Computers & Language Rehab From Singing to Speaking When the ...

  10. NASA Tech Briefs, April 1998. Volume 22, No. 4

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage on video and imaging, electronic components and circuits, electronic systems, physical sciences, materials, computer software, mechanics, machinery/automation, and a special section of Photonics Tech Briefs.

  11. Regional Emphysema Score Predicting Overall Survival, Quality of Life, and Pulmonary Function Recovery in Early-Stage Lung Cancer Patients.

    PubMed

    Dai, Jie; Liu, Ming; Swensen, Stephen J; Stoddard, Shawn M; Wampfler, Jason A; Limper, Andrew H; Jiang, Gening; Yang, Ping

    2017-05-01

    Pulmonary emphysema is a frequent comorbidity in lung cancer, but its role in tumor prognosis remains obscure. Our aim was to evaluate the impact of the regional emphysema score (RES) on a patient's overall survival, quality of life (QOL), and recovery of pulmonary function in stage I to II lung cancer. Between 1997 and 2009, a total of 1073 patients were identified and divided into two surgical groups-cancer in the emphysematous (group 1 [n = 565]) and nonemphysematous (group 2 [n = 435]) regions-and one nonsurgical group (group 3 [n = 73]). RES was derived from the emphysematous region and categorized as mild (≤5%), moderate (6%-24%), or severe (25%-60%). In group 1, patients with a moderate or severe RES experienced slight decreases in postoperative forced expiratory volume in 1 second, but increases in the ratio of forced expiratory volume in 1 second to forced vital capacity compared with those with a mild RES (p < 0.01); however, this correlation was not observed in group 2. Posttreatment QOL was lower in patients with higher RESs in all groups, mainly owing to dyspnea (p < 0.05). Cox regression analysis revealed that patients with a higher RES had significantly poorer survival in both surgical groups, with adjusted hazard ratios of 1.41 and 1.43 for a moderate RES and 1.63 and 2.04 for a severe RES, respectively; however, this association was insignificant in the nonsurgical group (adjusted hazard ratio of 0.99 for a moderate or severe RES). In surgically treated patients with cancer in the emphysematous region, RES is associated with postoperative changes in lung function. RES is also predictive of posttreatment QOL related to dyspnea in early-stage lung cancer. In both surgical groups, RES is an independent predictor of survival. Copyright © 2017 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

  12. Observation of three-dimensional elemental distributions of a Si device using a 360 degrees -tilt FIB and the cold field-emission STEM system.

    PubMed

    Yaguchi, Toshie; Konno, Mitsuru; Kamino, Takeo; Watanabe, Masashi

    2008-11-01

    A technique for preparation of a pillar-shaped specimen and its multidirectional observation using a combination of a scanning transmission electron microscope (STEM) and a focused ion beam (FIB) instrument has been developed. The system employs an FIB/STEM compatible holder with a specially designed tilt mechanism, which allows the specimen to be tilted through 360 degrees [T. Yaguchi, M. Konno, T. Kamino, T. Hashimoto, T. Ohnishi, K. Umemura, K. Asayama, Microsc. Microanal. 9 (Suppl. 2) (2003) 118; T. Yaguchi, M. Konno, T. Kamino, T. Hashimoto, T. Ohnishi, M. Watanabe, Microsc. Microanal. 10 (Suppl. 2) (2004) 1030]. This technique was applied to obtain the three-dimensional (3D) elemental distributions around a contact plug of a Si device used in a 90-nm technology. A specimen containing only one contact plug was prepared in the shape of a pillar with a diameter of 200nm and a length of 5mum. Elemental maps were obtained from the pillar specimen using a 200-kV cold-field emission gun (FEG) STEM model HD-2300C equipped with the EDAX genesis X-ray energy-dispersive spectrometry (XEDS) system through a spectrum imaging technique. In this study, elemental distributions of minor elements with weak signals were enhanced by applying principal component analysis (PCA), which is a superior technique to extract weak signals from a large dataset. The distributions of elements, especially the metallization component Ti and minor dopant As in this particular device, were successfully extracted by PCA. Finally, the 3D elemental distributions around the contact plug could be visualized by reconstruction from the tilt series of maps.

  13. Perceived impact of the 80-hour workweek: five years later.

    PubMed

    Dozois, Eric J; Holubar, Stefan D; Tsikitis, Vassiliki L; Malireddy, Kishore; Cima, Robert R; Farley, David R; Larson, David W

    2009-09-01

    We aimed to assess perceptions of the effects of the 80-hour workweek (80hWW) restriction on patient care, education, and resident quality of life. In April 2007, attending surgeons and residents in nine surgical specialties at our institution were surveyed. Respondents were categorized into three groups: (1) attending surgeons; (2) residents beginning their training before the 80hWW implementation (ResBefore); and (3) residents beginning training after the 80hWW implementation (ResAfter). Differences between groups were assessed with univariate analysis. The overall response rate was 57%. A minority in all three groups (< or =33%) believed the 80hWW improved patient care. Fifteen percent of attending surgeons, 30% of ResBefore, and 67% of ResAfter believed patients were safer (P < 0.001). Eighty-three percent of attending surgeons, 74% of ResBefore, and 41% of ResAfter (P < 0.001) believed continuity of care was compromised. All groups (> or =84%) agreed that midlevel providers were now critical to successfully deliver health care (P = 0.40). Fewer attending surgeons (21%) and ResBefore (29%) perceived improvements in education compared with ResAfter (68%; P <0.001). A majority perceived improved work-life balance for residents (attending surgeons [85%], ResBefore [71%], and ResAfter [92%]; P = 0.008), but 76% of attending surgeons reported decreased job satisfaction. We showed a discrepancy between perceptions of attending surgeons and residents regarding the effect of the 80hWW on patient care and surgical education. Quality of life was improved for residents but not for attending surgeons. The impact of the 80hWW on patient care and surgical education needs to be quantified.

  14. P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jia, Yongming

    The purpose of present study was to investigate the effect of resveratrol (Res) on altering methotrexate (MTX) pharmacokinetics and clarify the related molecular mechanism. Res significantly increased rat intestinal absorption of MTX in vivo and in vitro. Simultaneously, Res inhibited MTX efflux transport in MDR1-MDCK and MRP2-MDCK cell monolayers, suggesting that the target of drug interaction was MDR1 and MRP2 in the intestine during the absorption process. Furthermore, there was a significant decrease in renal clearance of MTX after simultaneous intravenous administration. Similarly, MTX uptake was markedly inhibited by Res in rat kidney slices and hOAT1/3-HEK293 cell, indicating that OAT1more » and OAT3 were involved in the drug interaction in the kidney. Additionally, concomitant administration of Res decreased cytotoxic effects of MTX in hOAT1/3-HEK293 cells, and ameliorated nephrotoxicity caused by MTX in rats. Conversely, intestinal damage caused by MTX was not exacerbated after Res treatment. In conclusion, Res enhanced MTX absorption in intestine and decreased MTX renal elimination by inhibiting P-gp, MRP2, OAT1 and OAT3 in vivo and in vitro. Res improved MTX-induced renal damage without increasing intestinal toxicity. - Highlights: • DDI between MTX and Res will occur when they are co-administered. • The first targets of the DDI are P-gp and MRP2 located in intestine. • The second targets of the DDI are OAT1 and OAT3 in kidney. • Res improved MTX-induced renal damage without increasing intestinal toxicity.« less

  15. Obesity-induced hepatic hypoperfusion primes for hepatic dysfunction after resuscitated hemorrhagic shock.

    PubMed

    Matheson, Paul J; Hurt, Ryan T; Franklin, Glen A; McClain, Craig J; Garrison, R Neal

    2009-10-01

    Obese patients (BMI>35) after blunt trauma are at increased risk compared to non-obese for organ dysfunction, prolonged hospital stay, infection, prolonged mechanical ventilation, and mortality. Obesity and non-alcoholic fatty liver disease (NAFLD) produce a low grade systemic inflammatory response syndrome (SIRS) with compromised hepatic blood flow, which increases with body mass index. We hypothesized that obesity further aggravates liver dysfunction by reduced hepatic perfusion following resuscitated hemorrhagic shock (HEM). Age-matched Zucker rats (Obese, 314-519 g & Lean, 211-280 g) were randomly assigned to 4 groups (n = 10-12/group): (1) Lean-Sham; (2) Lean, HEM, and resuscitation (HEM/RES); (3) Obese-Sham; and (4) Obese-HEM/RES. HEM was 40% of mean arterial pressure (MAP) for 60 min; RES was return of shed blood/5 min and 2 volumes of saline/25 min. Hepatic blood flow (HBF) using galactose clearance, liver enzymes and complete metabolic panel were measured over 4 h after completion of RES. Obese rats had increased MAP, heart rate, and fasting blood glucose and BUN concentrations compared to lean controls, required less blood withdrawal (mL/g) to maintain 40% MAP, and RES did not restore BL MAP. Obese rats had decreased HBF at BL and during HEM/RES, which persisted 4 h post RES. ALT and BUN were increased compared to Lean-HEM/RES at 4 h post-RES. These data suggest that obesity significantly contributes to trauma outcomes through compromised vascular control or through fat-induced sinusoidal compression to impair hepatic blood flow after HEM/RES resulting in a greater hepatic injury. The pro-inflammatory state of NAFLD seen in obesity appears to prime the liver for hepatic ischemia after resuscitated hemorrhagic shock, perhaps intensified by insidious and ongoing hepatic hypoperfusion established prior to the traumatic injury or shock.

  16. Evaluating uncertainty in predicting spatially variable representative elementary scales in fractured aquifers, with application to Turkey Creek Basin, Colorado

    USGS Publications Warehouse

    Wellman, Tristan P.; Poeter, Eileen P.

    2006-01-01

    Computational limitations and sparse field data often mandate use of continuum representation for modeling hydrologic processes in large‐scale fractured aquifers. Selecting appropriate element size is of primary importance because continuum approximation is not valid for all scales. The traditional approach is to select elements by identifying a single representative elementary scale (RES) for the region of interest. Recent advances indicate RES may be spatially variable, prompting unanswered questions regarding the ability of sparse data to spatially resolve continuum equivalents in fractured aquifers. We address this uncertainty of estimating RES using two techniques. In one technique we employ data‐conditioned realizations generated by sequential Gaussian simulation. For the other we develop a new approach using conditioned random walks and nonparametric bootstrapping (CRWN). We evaluate the effectiveness of each method under three fracture densities, three data sets, and two groups of RES analysis parameters. In sum, 18 separate RES analyses are evaluated, which indicate RES magnitudes may be reasonably bounded using uncertainty analysis, even for limited data sets and complex fracture structure. In addition, we conduct a field study to estimate RES magnitudes and resulting uncertainty for Turkey Creek Basin, a crystalline fractured rock aquifer located 30 km southwest of Denver, Colorado. Analyses indicate RES does not correlate to rock type or local relief in several instances but is generally lower within incised creek valleys and higher along mountain fronts. Results of this study suggest that (1) CRWN is an effective and computationally efficient method to estimate uncertainty, (2) RES predictions are well constrained using uncertainty analysis, and (3) for aquifers such as Turkey Creek Basin, spatial variability of RES is significant and complex.

  17. NASA Tech Briefs, November 2001. Volume 25, No. 11

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage section on data acquisition, and sections on electronic components and systems, software, materials, machinery/automation, physical sciences, book and reports, and a special section of Photonics Tech Briefs.

  18. Laying the Groundwork.

    ERIC Educational Resources Information Center

    Kretchmer, Mark R.

    2000-01-01

    Discusses how to avoid costly errors in high-tech retrofits through proper planning and coordination. Guidelines are offered for selecting cable installers, using multi-disciplinary consulting engineering firm, and space planning when making high-tech retrofits. (GR)

  19. NASA Tech Briefs, June 2002. Volume 26, No. 6

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on data acquisition, electronic components and systems, software, materials, mechanics, machinery/automation, physical sciences, book and reports, motion control, and a special section of Photonics Tech Briefs.

  20. Floor Plans Rolling Platform, Tech Systems Platform, and Load ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Floor Plans - Rolling Platform, Tech Systems Platform, and Load Platform Plans - Marshall Space Flight Center, F-1 Engine Static Test Stand, On Route 565 between Huntsville and Decatur, Huntsville, Madison County, AL

  1. NASA Tech Briefs, September 2001. Volume 25, No. 9

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage section on sensors, and sections on electronic components systems, software, materials, machinery/automation, manufacturing/fabrication, bio-medical, book and reports, and a special section of Photonics Tech Briefs.

  2. NASA Tech Briefs, May 2002. Volume 26, No. 5

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on engineering materials, electronic components and circuits, software, mechanics, machinery/automation, manufacturing, physical sciences, information sciences, book and reports, and a special section of Photonics Tech Briefs.

  3. NASA Tech Briefs, September 2002. Volume 26, No. 9

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on data acquisition, electronic components and systems, software, materials, mechanics, machinery/automation, bio-medical, physical sciences, book and reports, and a special section of Photonics Tech Briefs.

  4. Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.

    PubMed

    Wu, Haili; Wang, Yingying; Wu, Changxin; Yang, Peng; Li, Hanqing; Li, Zhuoyu

    2016-12-14

    Resveratrol (Res), a natural phytoalexin found in a variety of plants, has significant antitumor activity. Pyruvate kinase M2 (PKM2) has abnormally high expression in various tumor cells, and it has been implicated in the survival of tumors. However, whether and how Res inhibits PKM2 expression is poorly understood. In the present study, we found that treatment with Res inhibited cell proliferation and induced cell apoptosis. The IC 50 values of Res against DLD1, HeLa, and MCF-7 cells were 75 ± 4.54, 50 ± 3.65, and 50 ± 3.32 μM, respectively. To elucidate mechanisms underlying its antitumor activities, serial experiments were performed. Results showed that reduction of PKM2 expression in tumor cells by Res treatment increased the expression of ER stress and mitochondrial fission proteins but reduced cell viability and the levels of fusion proteins. These phenomena were reversed by artificial overexpression of PKM2. Quantitative analyses showed that the expression of microRNA-326 (miR-326) was increased upon Res treatment. Treatment with the miR-326 mimic reduced PKM2 expression, promoting recovery from ER stress and mitochondrial fission. Overall, these results demonstrate that miR-326/PKM2-mediated ER stress and mitochondrial dysfunction participate in apoptosis induced by Res. These results provide novel insight into the molecular mechanisms by which Res suppresses tumors and further support for the use of Res as an antitumor drug.

  5. Vertically oriented arrays of ReS 2 nanosheets for electrochemical energy storage and electrocatalysis

    DOE PAGES

    Gao, Jian; Li, Lu; Tan, Jiawei; ...

    2016-05-17

    Here, transition-metal dichalcogenide (TMD) nanolayers show potential as high-performance catalysts in energy conversion and storage devices. Synthetic TMDs produced by chemical-vapor deposition (CVD) methods tend to grow parallel to the growth substrate. Here, we show that with the right precursors and appropriate tuning of the CVD growth conditions, ReS 2 nanosheets can be made to orient perpendicular to the growth substrate. This accomplishes two important objectives; first, it drastically increases the wetted or exposed surface area of the ReS 2 sheets, and second, it exposes the sharp edges and corners of the ReS 2 sheets. We show that these structuralmore » features of the vertically grown ReS 2 sheets can be exploited to significantly improve their performance as polysulfide immobilizers and electrochemical catalysts in lithium–sulfur (Li–S) batteries and in hydrogen evolution reactions (HER). After 300 cycles, the specific capacity of the Li–S battery with vertical ReS 2 catalyst is retained above 750 mA h g –1, with only ~0.063% capacity decay per cycle, much better than the baseline battery (without ReS 2), which shows ~0.184% capacity decay per cycle under the same test conditions. As a HER catalyst, the vertical ReS 2 provides very small onset overpotential (<100 mV) and an exceptional exchange-current density (~67.6 μA/cm 2), which is vastly superior to the baseline electrode without ReS 2.« less

  6. Resveratrol and Cardiovascular Diseases

    PubMed Central

    Bonnefont-Rousselot, Dominique

    2016-01-01

    The increased incidence of cardiovascular diseases (CVDs) has stimulated research for substances that could improve cardiovascular health. Among them, resveratrol (RES), a polyphenolic compound notably present in grapes and red wine, has been involved in the “French paradox”. RES is known for its antioxidant and anti-inflammatory properties and for its ability to upregulate endothelial NO synthase (eNOS). RES was able to scavenge •OH/O2•− and peroxyl radicals, which can limit the lipid peroxidation processes. Moreover, in bovine aortic endothelial cells (BAEC) under glucose-induced oxidative stress, RES restored the activity of dimethylargininedimethylaminohydrolase (DDAH), an enzyme that degrades an endogenous inhibitor of eNOS named asymmetric dimethylarginine (ADMA). Thus, RES could improve •NO availability and decrease the endothelial dysfunction observed in diabetes. Preclinical studies have made it possible to identify molecular targets (SIRT-1, AMPK, Nrf2, NFκB…); however, there are limited human clinical trials, and difficulties in the interpretation of results arise from the use of high-dose RES supplements in research studies, whereas low RES concentrations are present in red wine. The discussions on potential beneficial effects of RES in CVDs (atherosclerosis, hypertension, stroke, myocardial infarction, heart failure) should compare the results of preclinical studies with those of clinical trials. PMID:27144581

  7. Low-Frequency Noise in Layered ReS2 Field Effect Transistors on HfO2 and Its Application for pH Sensing.

    PubMed

    Liao, Wugang; Wei, Wei; Tong, Yu; Chim, Wai Kin; Zhu, Chunxiang

    2018-02-28

    Layered rhenium disulfide (ReS 2 ) field effect transistors (FETs), with thickness ranging from few to dozens of layers, are demonstrated on 20 nm thick HfO 2 /Si substrates. A small threshold voltage of -0.25 V, high on/off current ratio of up to ∼10 7 , small subthreshold swing of 116 mV/dec, and electron carrier mobility of 6.02 cm 2 /V·s are obtained for the two-layer ReS 2 FETs. Low-frequency noise characteristics in ReS 2 FETs are analyzed for the first time, and it is found that the carrier number fluctuation mechanism well describes the flicker (1/f) noise of ReS 2 FETs with different thicknesses. pH sensing using a two-layer ReS 2 FET with HfO 2 as a sensing oxide is then demonstrated with a voltage sensitivity of 54.8 mV/pH and a current sensitivity of 126. The noise characteristics of the ReS 2 FET-based pH sensors are also examined, and a corresponding detection limit of 0.0132 pH is obtained. Our studies suggest the high potential of ReS 2 for future low-power nanoelectronics and biosensor applications.

  8. RES-loaded pegylated CS NPs: for efficient ocular delivery.

    PubMed

    Pandian, Saravanakumar; Jeevanesan, Vinoth; Ponnusamy, Chandrasekar; Natesan, Subramanian

    2017-02-01

    The objective of this study is to develop resveratrol (RES) loaded polyethylene glycols (PEGs) modified chitosan (CS) nanoparticles (NPs) by ionic gelation method for the treatment of glaucoma. While increasing the concentration of PEG, the particle size and polydispersity index of the formulations increased. Entrapment efficiency and RES loading (RL) of NPs decreased while increasing PEG concentration. The in vitro release of NPs showed an initial burst release of RES (45%) followed by controlled release. Osmolality of formulations revealed that the prepared NPs were iso-osmolar with the tear. Ocular tolerance of the NPs was evaluated using hen's egg test on the chorioallantoic membrane and it showed that the NPs were non-irritant. RES-loaded PEG-modified CS NPs shows an improved corneal permeation compared with RES dispersion. Fluorescein isothiocyanate loaded CS NPs accumulated on the surface of the cornea but the PEG-modified CS NPs crossed the cornea and reached retinal choroid. RES-loaded PEG-modified CS NPs reduced the intra-ocular pressure (IOP) by 4.3 ± 0.5 mmHg up to 8 h in normotensive rabbits. These results indicate that the developed NPs have efficient delivery of RES to the ocular tissues and reduce the IOP for the treatment of glaucoma.

  9. Hierarchical architecture of ReS2/rGO composites with enhanced electrochemical properties for lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Qi, Fei; Chen, Yuanfu; Zheng, Binjie; He, Jiarui; Li, Qian; Wang, Xinqiang; Lin, Jie; Zhou, Jinhao; Yu, Bo; Li, Pingjian; Zhang, Wanli

    2017-08-01

    Rhenium disulfide (ReS2), a two-dimensional (2D) semiconductor, has attracted more and more attention due to its unique anisotropic electronic, optical, mechanical properties. However, the facile synthesis and electrochemical property of ReS2 and its composite are still necessary to be researched. In this study, for the first time, the ReS2/reduced graphene oxide (rGO) composites have been synthesized through a facile and one-pot hydrothermal method. The ReS2/rGO composites exhibit a hierarchical, interconnected, and porous architecture constructed by nanosheets. As anode for lithium-ion batteries, the as-synthesized ReS2/rGO composites deliver a large initial capacity of 918 mAh g-1 at 0.2 C. In addition, the ReS2/rGO composites exhibit much better electrochemical cycling stability and rate capability than that of bare ReS2. The significant enhancement in electrochemical property can be attributed to its unique architecture constructed by nanosheets and porous structure, which can allow for easy electrolyte infiltration, efficient electron transfer, and ionic diffusion. Furthermore, the graphene with high electronic conductivity can provide good conductive passageways. The facile synthesis approach can be extended to prepare other 2D transition metal dichalcogenides semiconductors for energy storage and catalytic application.

  10. SciTech Clubs for Girls. [Annual] technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nogal, A.M.

    1993-02-01

    Since January 1992, 9 exhibits have been constructed by the SciTech Clubs for Girls, which involved 63 girls, ages 10 to 14. These exhibits are: Bubble Shapes by the St. Charles Cadette Girl Scout Troop No. 109. Density Games by the South Elgin Cadette Girl Scout Troop No. 132. Electric Fleas by the Warrenville Junior Girl Scout Troop No. 305. Energy vs. Power by the Aurora Junior Girl Scout Troop No. 242. The Organ Pipe by the Bartlett Junior Girl Scout Troop No. 107. Ohm`s Law by the Geneva Junior Girl Scout Troop No. 401. What is Gravity by themore » Pilsen YMCA girls. Insulation at Work by the Algonquin Junior Girl Scout Troop No. 303. Series vs. Parallel by the Leland Junior Girl Scout Troop No. 50. The report is a description of each exhibit and the group that built the exhibit. Each group had a minimum of 10 hours of contact time at SciTech with the SciTech Clubs for Girls Program Coordinator. All mentors are female. Each exhibit building experience includes a trip to the hardware store to purchase supplies. After the exhibit is complete, the girls receive certificates of achievement and a SciTech Club Patch.« less

  11. NASA Tech Briefs, November 2002. Volume 26, No. 11

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on engineering materials, electronic components and systems, software, mechanics, machinery/automation, manufacturing, bio-medical, physical sciences, information sciences book and reports, and a special section of Photonics Tech Briefs.

  12. NASA Tech Briefs, August 2001. Volume 25, No. 8

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage section on computers and peripherals, and sections on electronic components systems, software, materials, mechanics, manufacturing/fabrication, physical sciences, book and reports, and a special section of Motion Control Tech Briefs.

  13. NASA Tech Briefs, October 2002. Volume 26, No. 10

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus on sensors, electronic components and systems, software, materials, materials, mechanics, manufacturing, physical sciences, information sciences, book and reports, motion control and a special section of Photonics Tech Briefs.

  14. NASA Tech Briefs, March 2002. Volume 26, No. 3

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a special section on data acquisition, software, electronic components and systems, materials, computer programs, mechanics, machinery/automation, manufacturing, biomedical, physical sciences, book and reports, and a special section of Photonics Tech Briefs.

  15. Concrete pavement construction basics : tech notes.

    DOT National Transportation Integrated Search

    2006-08-01

    This tech note has been produced for developers, consultants, and engineers planning concrete pavement construction projects, superintendents and supervisors who want a basic training aid and reference, and crew members new to the concrete paving ind...

  16. NASA Tech Briefs, July 2002. Volume 26, No. 7

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Topics include: a technology focus sensors, software, electronic components and systems, materials, mechanics, machinery/automation, manufacturing, bio-medical, physical sciences, information sciences, book and reports, and a special section of Photonics Tech Briefs.

  17. NASA Tech Briefs Index, 1977, volume 2, numbers 1-4

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Announcements of new technology derived from the research and development activities of NASA are presented. Abstracts, and indexes for subject, personal author, originating center, and Tech Brief number are presented for 1977.

  18. Epitaxial growth of ReS2(001) thin film via deposited-Re sulfurization

    NASA Astrophysics Data System (ADS)

    Urakami, Noriyuki; Okuda, Tetsuya; Hashimoto, Yoshio

    2018-02-01

    In this paper, we present the formation of large-size rhenium disulfide (ReS2) films via the sulfurization of Re films deposited on sapphire substrates. The effects of sulfurization temperature and pressure on the crystal quality were investigated. A [001]-oriented single crystal of ReS2 films with 6 × 10 mm2 area was realized. By sulfurizing Re films at 1100 °C, ReS2 films with well-defined sharp interfaces to c-plane sapphire substrates could be formed. Below and above the sulfurization temperature of 1100 °C, incomplete sulfurization and film degradation were observed. The twofold symmetry of the monocrystalline in-plane structure composed of Re-Re bonds along with Re-S bonds pointed to a distorted 1T structure, indicating that this structure is the most stable atomic arrangement for ReS2. For a S/Re compositional ratio equal to or slightly lower than 2.0, characteristic Raman vibrational modes with the narrowest line widths were observed. The typical absorption peak of ReS2 can be detected at 1.5 eV.

  19. Residual Deep Convolutional Neural Network Predicts MGMT Methylation Status.

    PubMed

    Korfiatis, Panagiotis; Kline, Timothy L; Lachance, Daniel H; Parney, Ian F; Buckner, Jan C; Erickson, Bradley J

    2017-10-01

    Predicting methylation of the O6-methylguanine methyltransferase (MGMT) gene status utilizing MRI imaging is of high importance since it is a predictor of response and prognosis in brain tumors. In this study, we compare three different residual deep neural network (ResNet) architectures to evaluate their ability in predicting MGMT methylation status without the need for a distinct tumor segmentation step. We found that the ResNet50 (50 layers) architecture was the best performing model, achieving an accuracy of 94.90% (+/- 3.92%) for the test set (classification of a slice as no tumor, methylated MGMT, or non-methylated). ResNet34 (34 layers) achieved 80.72% (+/- 13.61%) while ResNet18 (18 layers) accuracy was 76.75% (+/- 20.67%). ResNet50 performance was statistically significantly better than both ResNet18 and ResNet34 architectures (p < 0.001). We report a method that alleviates the need of extensive preprocessing and acts as a proof of concept that deep neural architectures can be used to predict molecular biomarkers from routine medical images.

  20. Shaking Up Biotech/Pharma: Can Cues Be Taken from the Tech Industry?

    PubMed

    Wang, C Katherine

    2017-06-01

    The biotech and pharma (biotech/pharma) industry is in dire need of finding ways to increase efficacy, efficiency, and affordability of its products. The information and technology industry ("tech") industry, which is an industry similarly founded on inventions and innovation, may provide some food for thought. This perspective will demonstrate the shift that biotech/pharma is already making and will propose that the industry has an opportunity to compel change by adopting some aspects of the tech industry with regards to models for technology/product development and leadership attributes.

  1. Report on Workshop on Research in Experimental Computer Science Held in Palo Alto, California on 16-18 October 1991

    DTIC Science & Technology

    1992-06-01

    HiTech was the highest ranked chess ma- chine between 1985 and 1988, and the three things that were key to HiTech’s success ’D. S. Johnson and C. C...colleagues to help him understand anomalies. Hans Berliner discussed the HiTech chess machine. This was a small project that began with a new idea of one of...light. 4. Proposals to do experimental research should have detailed sections on the method- ology and the criteria that would constitute success of

  2. Economic Analysis Model Evaluation for Technology Modernization Programs.

    DTIC Science & Technology

    1983-09-01

    program and ’ expost - facto ’ utilized the ASD model to evaluate the accuracy of the ASD model. The following chapter reviews the literature on Tech Mod and...was applied to the CAR 80 Tech Mod project ’ expost - facto ’ in order to develop an ASD model estimated rate o . return. The ASD model was applied in...ASD estimate to achieve a range for the actual IRR. The ASD model was applied expost - facto to the CAR 80 Tech Mod program to derive an IRR. Initial data

  3. When the brain does not adequately feel the body: Links between low resilience and interoception.

    PubMed

    Haase, Lori; Stewart, Jennifer L; Youssef, Brittany; May, April C; Isakovic, Sara; Simmons, Alan N; Johnson, Douglas C; Potterat, Eric G; Paulus, Martin P

    2016-01-01

    This study examined neural processes of resilience during aversive interoceptive processing. Forty-six individuals were divided into three groups of resilience Low (LowRes), high (HighRes), and normal (NormRes), based on the Connor-Davidson Resilience Scale (2003). Participants then completed a task involving anticipation and experience of loaded breathing during functional magnetic resonance imaging (fMRI) recording. Compared to HighRes and NormRes groups, LowRes self-reported lower levels of interoceptive awareness and demonstrated higher insular and thalamic activation across anticipation and breathing load conditions. Thus, individuals with lower resilience show reduced attention to bodily signals but greater neural processing to aversive bodily perturbations. In low resilient individuals, this mismatch between attention to and processing of interoceptive afferents may result in poor adaptation in stressful situations. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Technology Components as Adjuncts to Family-Based Pediatric Obesity Treatment in Low-Income Minority Youth.

    PubMed

    Tripicchio, Gina L; Ammerman, Alice S; Neshteruk, Cody; Faith, Myles S; Dean, Kelsey; Befort, Christie; Ward, Dianne S; Truesdale, Kimberly P; Burger, Kyle S; Davis, Ann

    2017-12-01

    Strategies to treat pediatric obesity are needed, especially among high-need populations. Technology is an innovative approach; however, data on technology as adjuncts to in-person treatment programs are limited. A total of 64 children [body mass index (BMI) ≥85th percentile, mean age = 9.6 ± 3.1 years, 32.8% female, 84.4% Hispanic] were recruited to participate in one of three cohorts of a family-based behavioral group (FBBG) treatment program: FBBG only, TECH1, and TECH2. Rolling, nonrandomized recruitment was used to enroll participants into three cohorts from May 2014 to February 2015. FBBG began in May 2014 and received the standard, in-person 12-week treatment only (n = 21); TECH1 began in September 2014 and received FBBG plus a digital tablet equipped with a fitness app (FITNET) (n = 20); TECH2 began in February 2015 and received FBBG and FITNET, plus five individually tailored TeleMed health-coaching sessions delivered via Skype (n = 23). Child BMI z-score (BMI-z) was assessed at baseline and postintervention. Secondary aims examined weekly FBBG attendance, feasibility/acceptability of FITNET and Skype, and the effect of technology engagement on BMI-z. FBBG and TECH1 participants did not show significant reductions in BMI-z postintervention [FBBG: β = -0.05(0.04), p = 0.25; TECH1: β = -0.006(0.06), p = 0.92], but TECH2 participants did [β = -0.09(0.02), p < 0.001] and TeleMed session participation was significantly associated with BMI-z reduction [β = -0.04(0.01), p = 0.01]. FITNET use and FBBG attendance were not associated with BMI-z in any cohort. Overall, participants rated the technology as highly acceptable. Technology adjuncts are feasible, used by hard-to-reach participants, and show promise for improving child weight status in obesity treatment programs.

  5. Gestion de la douleur chronique par les infirmières des Groupes de médecine de famille

    PubMed Central

    Bergeron, Dave A; Bourgault, Patricia; Gallagher, Frances

    2015-01-01

    INTRODUCTION : Des milliers de personnes souffrent actuellement de douleur chronique (DC) pour laquelle la prise en charge s’avère souvent inadéquate. Au Québec, les infirmières qui oeuvrent dans les Groupes de médecine de famille (GMF) jouent un rôle clé dans le suivi des personnes aux prises avec des problèmes de santé chroniques dont la DC. OBJECTIFS : Cette étude a pour objectifs de décrire les activités réalisées par les infirmières œuvrant en GMF en lien avec la gestion de la douleur chez la clientèle souffrant de DC, ainsi que les barrières à ces activités. MÉTHODE : Un dispositif descriptif corrélationnel transversal de type enquête postale a été utilisé. La population accessible à l’étude comprend les infirmières qui figurent sur la liste des membres de l’Ordre des infirmières et infirmiers du Québec travaillant en GMF. L’ensemble des infirmières figurant sur cette liste ayant consenti à être contactées à leur domicile pour des fins de recherche ont été contactées. Un questionnaire postal auto-administré (Pain Management Activities Questionnaire) a été complété par 53 infirmières travaillant en GMF. RÉSULTATS : Les trois activités le plus souvent réalisées par les infirmières sont d’établir une relation thérapeutique avec le client; de discuter avec le médecin de l’efficacité des mesures thérapeutiques et de faire un enseignement personnalisé au client. Les infirmières ont la perception qu’elles rencontrent en moyenne 2,68 personnes par semaine qui souffrent de DC. La méconnaissance des interventions possibles en douleur (71,7%) et la non-disponibilité de l’information sur la gestion de la douleur (52,8%) constituent les principales barrières selon les infirmières sondées. CONCLUSION : Les infirmières au sein des GMF font actuellement peu d’activités en gestion de la DC probablement en raison du manque de reconnaissance de la DC. PMID:25848847

  6. TxDOT wildland fire management training.

    DOT National Transportation Integrated Search

    2014-06-01

    In 2011, the Texas Tech Center for Multidisciplinary Research in Transportation (TechMRT) was contracted by the Texas Department of Transportation (TxDOT) to analyze best practices for the department in responding to wildfires. This project (0-6735) ...

  7. NASA Tech Briefs, May 1998. Volume 22, No. 5

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage on advanced composites, plastics and metals, electronic components and circuits, electronic systems, physical sciences, computer software, mechanics, machinery/automation, manufacturing/fabrication book and reports, and a special section of Electronics Tech Briefs.

  8. Georgia Tech

    Science.gov Websites

    Family Programs Dean of Students Scholarships & Financial Aid Employee, Alumni, & Other Resources Education Georgia Tech Online Academic Calendar Admissions Prospective Students Admissions Overview roots extend worldwide, creating international business connections and giving students unique research

  9. NASA Tech Briefs, January 1999. Volume 23, Mp/ 1

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Topics include: special coverage sections on sensors and data acquisition and sections on electronic components and circuits, electronic software, materials, mechanics, bio-medical physical sciences, book and reports, and a special section of Photonics Tech Briefs.

  10. Training for healthy older drivers : traffic tech.

    DOT National Transportation Integrated Search

    2013-05-01

    The research described in this edition of "Traffic Tech" examined the effectiveness of four types of : training techniques designed to improve the driving performance : of normally aging adults. Each technique is suitable : for a broad cross-section ...

  11. NASA Tech Briefs, July 1995. Volume 19, No. 7

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Topics include: mechanical components, electronic components and circuits, electronic systems, physical sciences, materials, computer programs, mechanics, machinery, manufacturing/fabrication, mathematics and information sciences, book and reports, and a special section of Federal laboratory computing Tech Briefs.

  12. Minnesota's Tech Prep Outcome Evaluation Model.

    ERIC Educational Resources Information Center

    Brown, James M.; Pucel, David; Twohig, Cathy; Semler, Steve; Kuchinke, K. Peter

    1998-01-01

    Describes the Minnesota Tech Prep Consortia Evaluation System, which collects outcomes data on enrollment, retention, related job placement, higher education, dropouts, and diplomas/degrees awarded. Explains outcome measures, database development, data collection and analysis methods, and remaining challenges. (SK)

  13. Watershed Modeling Recommendation Report for Lake Champlain TMDL

    EPA Pesticide Factsheets

    This report describes the recommended modeling approach for watershed modeling component of the Lake Champlain TMDL project. The report was prepared by Tetra Tech, with input from the Lake Champlain watershed analysis workgroup. (TetraTech, 2012a)

  14. NASA Tech Briefs, June 1995. Volume 19, No. 6

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Topics include: communications technology, electronic components and circuits, electronic systems, physical sciences, materials, computer programs, mechanics, machinery, manufacturing/fabrication, mathematics and information sciences, life sciences, books and reports, a special section of laser Tech Briefs.

  15. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 27: Knowledge diffusion and US government technology policy: Issues and opportunities for sci/tech librarians

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Hannah, Stan; Lawrence, Barbara; Kennedy, John M.

    1992-01-01

    Federal involvement in simulating economic growth through the development and application of technology policy is currently the subject of serious debate. A recession and the recognition that an internationally competitive economy is a prerequisite for the attainment of national goals have fostered a number of technology policy initiatives aimed at improving the economic competitiveness of American industry. This paper suggests that the successful implementation of U.S. technology policy will require the adoption of a knowledge diffusion model, the development of user oriented information products and services, and a more 'activist' approach on the part of sci/tech librarians in the provision of scientific and technical information (STI). These changes will have a dramatic impact on the sci/tech library of the future and the preparation of sci/tech librarians.

  16. NASA/DoD Aerospace Knowledge Diffusion Research Project. XXVII - Knowledge diffusion and U.S. government technology policy: Issues and opportunities for sci/tech librarians

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Hannah, Stan; Lawrence, Barbara; Kennedy, John M.

    1992-01-01

    Federal involvement in stimulating economic growth through the development and application of technology policy is currently the subject of serious debate. A recession and the recognition that an internationally competitive economy is a prerequisite for the attainment of national goals have fostered a number of technology policy initiatives aimed at improving the economic competitiveness of American industry. This paper suggests that the successful implementation of U.S. technology policy will require the adoption of a knowledge diffusion model, the development of user oriented information products and services, and a more 'activist' approach on the part of sci/tech librarians in the provision of scientific and technical information (STI). These changes will have a dramatic impact on the sci/tech library of the future and the preparation of sci/tech librarians.

  17. Evaluate the ability of PVP to inhibit crystallization of amorphous solid dispersions by density functional theory and experimental verify.

    PubMed

    Wang, Bing; Wang, Dandan; Zhao, Shan; Huang, Xiaobin; Zhang, Jianbin; Lv, Yan; Liu, Xiaocen; Lv, Guojun; Ma, Xiaojun

    2017-01-01

    In this study, we used density functional theory (DFT) to predict polymer-drug interactions, and then evaluated the ability of poly (vinyl pyrrolidone) (PVP) to inhibit crystallization of amorphous solid dispersions by experimental-verification. Solid dispersions of PVP/resveratrol (Res) and PVP/griseofulvin (Gri) were adopted for evaluating the ability of PVP to inhibit crystallization. The density functional theory (DFT) with the B3LYP was used to calculate polymer-drug and drug-drug interactions. Fourier transform infrared spectroscopy (FTIR) was used to confirm hydrogen bonding interactions. Polymer-drug miscibility and drug crystallinity were characterized by the modulated differential scanning calorimetry (MDSC) and X-ray powder diffraction (XRD). The release profiles were studied to investigate the dissolution advantage. DFT results indicated that E PVP-Res >E Res-Res (E: represents hydrogen bonding energy). A strong interaction was formed between PVP and Res. In addition, Fourier transform infrared spectroscopy (FTIR) analysis showed hydrogen bonding formed between PVP and Res, but not between PVP and Gri. MDSC and XRD results suggested that 70-90wt% PVP/Res and PVP/Gri solid dispersions formed amorphous solid dispersions (ASDs). Under the accelerated testing condition, PVP/Res dispersions with higher miscibility quantified as 90/10wt% were more stable than PVP/Gri dispersions. The cumulative dissolution rate of 90wt% PVP/Res dispersions still kept high after 90days storage due to the strong interaction. However, the cumulative dissolution rate of PVP/Gri solid dispersions significantly dropped because of the recrystallization of Gri. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Southeast Regional Experiment Station

    NASA Astrophysics Data System (ADS)

    1994-08-01

    This is the final report of the Southeast Regional Experiment Station project. The Florida Solar Energy Center (FSEC), a research institute of the University of Central Florida (UCF), has operated the Southeast Regional Experiment Station (SE RES) for the US Department of Energy (DOE) since September 1982. Sandia National Laboratories, Albuquerque (SNLA) provides technical program direction for both the SE RES and the Southwest Regional Experiment Station (SW RES) located at the Southwest Technology Development Institute at Las Cruces, New Mexico. This cooperative effort serves a critical role in the national photovoltaic program by conducting system evaluations, design assistance and technology transfer to enhance the cost-effective utilization and development of photovoltaic technology. Initially, the research focus of the SE RES program centered on utility-connected PV systems and associated issues. In 1987, the SE RES began evaluating amorphous silicon (a-Si) thin-film PV modules for application in utility-interactive systems. Stand-alone PV systems began receiving increased emphasis at the SE RES in 1986. Research projects were initiated that involved evaluation of vaccine refrigeration, water pumping and other stand-alone power systems. The results of this work have led to design optimization techniques and procedures for the sizing and modeling of PV water pumping systems. Later recent research at the SE RES included test and evaluation of batteries and charge controllers for stand-alone PV system applications. The SE RES project provided the foundation on which FSEC achieved national recognition for its expertise in PV systems research and related technology transfer programs. These synergistic products of the SE RES illustrate the high visibility and contributions the FSEC PV program offers to the DOE.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mohapatra, Purusottam; Satapathy, Shakti Ranjan; Das, Dipon

    Cigarette smoking is a key factor for the development and progression of different cancers including mammary tumor in women. Resveratrol (Res) is a promising natural chemotherapeutic agent that regulates many cellular targets including p21, a cip/kip family of cyclin kinase inhibitors involved in DNA damage-induced cell cycle arrest and blocking of DNA replication and repair. We have recently shown that cigarette smoke condensate (CSC) prepared from commercially available Indian cigarette can cause neoplastic transformation of normal breast epithelial MCF-10A cell. Here we studied the mechanism of Res mediated apoptosis in CSC transformed (MCF-10A-Tr) cells in vitro and in vivo. Resmore » mediated apoptosis in MCF-10A-Tr cells was a p21 dependent event. It increased the p21 protein expression in MCF-10A-Tr cells and MCF-10A-Tr cells-mediated tumors in xenograft mice. Res treatment reduced the tumor size(s) and expression of anti-apoptotic proteins (e.g. PI3K, AKT, NFκB) in solid tumor. The expressions of cell cycle regulatory (Cyclins, CDC-2, CDC-6, etc.), BER associated (Pol-β, Pol-δ, Pol-ε, Pol-η, RPA, Fen-1, DNA-Ligase-I, etc.) proteins and LP-BER activity decreased in MCF-10A-Tr cells but remain significantly unaltered in isogenic p21 null MCF-10A-Tr cells after Res treatment. Interestingly, no significant changes were noted in SP-BER activity in both the cell lines after Res exposure. Finally, it was observed that increased p21 blocks the LP-BER in MCF-10A-Tr cells by increasing its interaction with PCNA via competing with Fen-1 after Res treatment. Thus, Res caused apoptosis in CSC-induced cancer cells by reduction of LP-BER activity and this phenomenon largely depends on p21. - Highlights: • Resveratrol (Res) caused reduction of MCF-10A-Tr cell growth by inducing apoptosis. • Res caused cell cycle arrest and DNA damage in p21 dependent manner. • Res mediated LP-BER reduction in MCF-10A-Tr cells was a p21 dependent phenomenon. • Res inhibits BER and PI3K, AKT, and NFκB protein expressions in tumor and xenografts. • Res-induced-p21 inhibited DNA repair by modulating Fen-1 binding to PCNA complex.« less

  20. Dietary resveratrol supplementation prevents transport-stress-impaired meat quality of broilers through maintaining muscle energy metabolism and antioxidant status

    PubMed Central

    Zhang, C.; Wang, L.; Zhao, X. H.; Chen, X. Y.; Yang, L.; Geng, Z. Y.

    2017-01-01

    Abstract This experiment was to evaluate the effect of dietary resveratrol (Res) supplementation (0, 400 mg/kg) on growth performance, meat quality, and muscle anaerobic glycolysis and antioxidant capacity of transported broilers. A total of 360 21-day-old male Cobb broilers was randomly allotted to 2 dietary treatments (Res-free group and Res group) with 12 replicates of 15 birds each. On the morning of d 42, after a 9-hour fast, 24 birds (2 birds of each replicate) were selected from the Res-free group and then equally placed into 2 crates, and the other 12 birds (one bird of each replicate) were selected from the Res group and then placed into the other crate. All birds in the 3 crates were transported according to the following protocols: 0-hour transport of birds in the Res-free group (control group), 3-hour transport of birds in the Res-free group (T group), and 3-hour transport of birds in the Res group (T + Res group). The results showed that Res not only improved feed conversion ratio (P < 0.05) but also tended to improve birds’ final body weight (P < 0.10). In the Res-free group, a 3-hour transport increased serum corticosterone concentration, muscle malondialdehyde (MDA) and lactate contents, and muscle lactate dehydrogenase (LDH) activity, while it decreased muscle glycogen content, total superoxide dismutase (T-SOD), and glutathione peroxidase (GSH-PX) activities (P < 0.05), which induced decreased breast meat quality (lower pH24h and higher drip loss and L*24 h, P < 0.05). Nevertheless, compared with the T group, Res increased muscle glycogen content and T-SOD and GSH-PX activities (P < 0.05 or P < 0.10), while it decreased muscle MDA content and LDH activity (P < 0.05), which is beneficial to the meat quality maintenance of transported broilers (lower drip loss, L*24 h, and higher pH24h, P < 0.05 or P < 0.10). This study provides the first evidence that dietary resveratrol supplementation prevents transport-stress-impaired meat quality of broilers, possibly through decreasing the muscle anaerobic glycolysis metabolism and improving the muscle antioxidant capacity. PMID:28339929

  1. Hypoglycemic depression of RES function.

    PubMed

    Buchanan, B J; Filkins, J P

    1976-07-01

    The intravascular removal rates of colloidal carbon and of biologically active endotoxin by the reticuloendothelial system (RES) were evaluated as a function of blood-glucose levels. There was a significant negative correlation of carbon clearance half time on blood glucose in both saline-treated and insulin-treated rats. Insulin hypoglycemia depressed RES carbon clearance with the maximal effect occurring at blood glucose values below 30 mg/dl. Insulin hypoglycemia also severely impaired the intravascular removal of endotoxin as evaluated by lethality bioassay in lead-sensitized rats. It is concluded that blood glucose may modulate RES phagocytic function and that the hypoglycemia of endotoxin shock may augment the shock state due to impairment of RES host defense clearance functions.

  2. Inventory of File sref_nmb.t03z.pgrb221.ctl.grib2

    Science.gov Websites

    006 10 m above ground UGRD analysis U-Component of Wind [m/s] ENS=low-res ctl 007 10 m above ground VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl 008 surface WEASD analysis Water Equivalent of -Component of Wind [m/s] ENS=low-res ctl 021 250 mb VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl

  3. Inventory of File sref_nmb.t03z.pgrb132.ctl.grib2

    Science.gov Websites

    006 10 m above ground UGRD analysis U-Component of Wind [m/s] ENS=low-res ctl 007 10 m above ground VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl 008 surface WEASD analysis Water Equivalent of -Component of Wind [m/s] ENS=low-res ctl 021 250 mb VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl

  4. Inventory of File sref_nmb.t03z.pgrb243.ctl.grib2

    Science.gov Websites

    006 10 m above ground UGRD analysis U-Component of Wind [m/s] ENS=low-res ctl 007 10 m above ground VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl 008 surface WEASD analysis Water Equivalent of -Component of Wind [m/s] ENS=low-res ctl 021 250 mb VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl

  5. Inventory of File sref_nmb.t03z.pgrb216.ctl.grib2

    Science.gov Websites

    006 10 m above ground UGRD analysis U-Component of Wind [m/s] ENS=low-res ctl 007 10 m above ground VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl 008 surface WEASD analysis Water Equivalent of -Component of Wind [m/s] ENS=low-res ctl 021 250 mb VGRD analysis V-Component of Wind [m/s] ENS=low-res ctl

  6. Exploring Astrobiology: Future and In-Service Teacher Research Experiences

    NASA Astrophysics Data System (ADS)

    Cola, J.; Williams, L. D.; Snell, T.; Gaucher, E.; Harris, B.; Usselman, M. C.; Millman, R. S.

    2009-12-01

    The Georgia Tech Center for Ribosome Adaptation and Evolution, a center funded by the NASA Astrobiology Institute, developed an educational Astrobiology program titled, “Life on the Edge: Astrobiology.” The purpose of the program was to provide educators with the materials, exposure, and skills necessary to prepare our future workforce and to foster student interest in scientific discovery on Earth and throughout the universe. A one-week, non-residential summer enrichment program for high school students was conducted and tested by two high school educators, an undergraduate student, and faculty in the Schools of Biology, and Chemistry and Biochemistry at Georgia Tech. In an effort to promote and encourage entry into teaching careers, Georgia Tech paired in-service teachers in the Georgia Intern-Fellowship for Teachers (GIFT) program with an undergraduate student interested in becoming a teacher through the Tech to Teaching program. The GIFT and Tech to Teaching fellows investigated extremophiles which have adapted to life under extreme environmental conditions. As a result, extremophiles became the focus of a week-long, “Life on the Edge: Astrobiology” curriculum aligned with the Georgia Performance Standards in Biology. Twenty-five high school students explored the adaptation and survival rates for various types of extremophiles exposed to UV radiation and desiccation; students were also introduced to hands-on activities and techniques such as genomic DNA purification, gel electrophoresis, and Polymerase Chain Reaction (PCR). The impact on everyone invested and involved in the Astrobiology program including the GIFT and Tech to Teaching fellows, high school students, and faculty are discussed.

  7. Resveratrol ameliorates chronic unpredictable mild stress-induced depression-like behavior: involvement of the HPA axis, inflammatory markers, BDNF, and Wnt/β-catenin pathway in rats.

    PubMed

    Yang, Xin-Hua; Song, Su-Qi; Xu, Yun

    2017-01-01

    Classic antidepressant drugs are modestly effective across the population and most are associated with intolerable side effects. Recently, numerous lines of evidence suggest that resveratrol (RES), a natural polyphenol, possesses beneficial therapeutic activity for depression. The aim of the present study was to explore whether RES exhibits an antidepressant-like effect in a depression model and to explore the possible mechanism. A depression model was established via chronic unpredictable mild stress (CUMS), after which the model rats in the RES and fluoxetine groups received a daily injection of RES or fluoxetine, respectively. The sucrose preference test, open field test, and forced swimming test were used to explore the antidepressant-like effects of RES. The activity of the hypothalamic-pituitary-adrenal (HPA) axis was evaluated by detecting the plasma corticosterone concentration and hypothalamic mRNA expression of corticotrophin-releasing hormone. The plasma interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) concentrations were measured by enzyme-linked immunosorbent assay. Hippocampal protein expression of brain-derived neurotrophic factor (BDNF) and the Wnt/β-catenin pathway were analyzed by western blot. The results showed that RES relieved depression-like behavior of CUMS rats, as indicated by the increased sucrose preference and the decreased immobile time. Rats that received RES treatment exhibited reduced plasma corticosterone levels and corticotrophin-releasing hormone mRNA expression in the hypothalamus, suggesting that the hyperactivity of the HPA axis in CUMS rats was reversed by RES. Moreover, after RES treatment, the rats exhibited increased plasma IL-6, CRP, and TNF-α concentrations. Furthermore, RES treatment upregulated the hippocampal protein levels of BDNF and the relative ratio of p-β-catenin/β-catenin while downregulating the relative ratio of p-GSK-3β/GSK-3β. Our findings suggest that RES improved depressive behavior in CUMS rats by downregulating HPA axis hyperactivity, increasing BDNF expression and plasma IL-6, CRP, and TNF-α concentrations, and regulating the hippocampal Wnt/β-catenin pathway.

  8. Self-Protecting Security for Assured Information Sharing

    DTIC Science & Technology

    2015-08-29

    by Author Sophia Novitzky (Senior), Virginia Tech Mahalia Sapp (Senior), Virginia Tech Performance Sensitivity in Vertical Geothermal Energy...Harvesting Systems 9:15 AM, Annapolis Room, Student Center Residential geothermal energy systems have the potential to provide a cost-effective, low

  9. In-lake Modeling Recommendation Report for Lake Champlain TMDL

    EPA Pesticide Factsheets

    This report describes the recommended modeling approach for the in-lake modeling component of the Lake Champlain TMDL project. The report was prepared by Tetra Tech, with input from the Lake Champlain modeling workgroup. (TetraTech, 2012b)

  10. Proceedings of Denver GeoTech '92

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roberts, C.A.

    1992-01-01

    This book contains proceedings of Denver Geo Tech '92. Topics covered include: practical ways to use microcomputers and workstations in geology, geophysics, environmental concerns, petroleum engineering, mining, hydrogeology, reclamation, microcomputers, state-of-the-art information on computer hardware, software, and services.

  11. Tech-Prep Competency Profiles within the Health Technologies Cluster.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains competency profiles for Ohio tech prep courses in the following 12 health technologies occupations: radiographer, respiratory care therapist, occupational therapy assistant, physical therapist assistant, registered nurse (associate degree), pharmacy technologist, medical laboratory technician, histotechnologist, emergency…

  12. Protocol for selecting ASR-affected structures for lithium treatment

    DOT National Transportation Integrated Search

    2006-02-01

    This TechBrief describes a protocol for evaluating damaged concrete structures to determine whether they are suitable candidates for lithium treatment to address alkali-silica reactivity (ASR). A major part of the TechBrief's source document, Protoco...

  13. TechNovation Lecture Series

    NASA Image and Video Library

    2011-02-17

    Karim R. Lakhani, assistant professor at Harvard Business School, kicked off the Office of the Chief Technologist TechNovation Lecture series with his talk "Accessing the Ideas Cloud" on Thursday, Feb. 17, 2011 at NASA Headquarters in Washington. Photo Credit: (NASA/Carla Cioffi)

  14. Detection of colorectal masses in CT colonography: application of deep residual networks for differentiating masses from normal colon anatomy

    NASA Astrophysics Data System (ADS)

    Näppi, Janne J.; Hironaka, Toru; Yoshida, Hiroyuki

    2018-02-01

    Even though the clinical consequences of a missed colorectal cancer far outweigh those of a missed polyp, there has been little work on computer-aided detection (CADe) for colorectal masses in CT colonography (CTC). One of the problems is that it is not clear how to manually design mathematical image-based features that could be used to differentiate effectively between masses and certain types of normal colon anatomy such as ileocecal valves (ICVs). Deep learning has demonstrated ability to automatically determine effective discriminating features in many image-based problems. Recently, residual networks (ResNets) were developed to address the practical problems of constructing deep network architectures for optimizing the performance of deep learning. In this pilot study, we compared the classification performance of a conventional 2D-convolutional ResNet (2D-ResNet) with that of a volumetric 3D-convolutional ResNet (3D-ResNet) in differentiating masses from normal colon anatomy in CTC. For the development and evaluation of the ResNets, 695 volumetric images of biopsy-proven colorectal masses, ICVs, haustral folds, and rectal tubes were sampled from 196 clinical CTC cases and divided randomly into independent training, validation, and test datasets. The training set was expanded by use of volumetric data augmentation. Our preliminary results on the 140 test samples indicate that it is feasible to train a deep volumetric 3D-ResNet for performing effective image-based discriminations in CTC. The 3D-ResNet slightly outperformed the 2D-ResNet in the discrimination of masses and normal colon anatomy, but the statistical difference between their very high classification accuracies was not significant. The highest classification accuracy was obtained by combining the mass-likelihood estimates of the 2D- and 3D-ResNets, which enabled correct classification of all of the masses.

  15. A dichotomy in primary marine organic aerosol-cloud-climate system

    NASA Astrophysics Data System (ADS)

    Ceburnis, D.; Ovadnevaite, J.; Martucci, G.; Bialek, J.; Monahan, C.; Rinaldi, M.; Facchini, C.; Berresheim, H.; Worsnop, D. R.; O'Dowd, C.

    2011-12-01

    D. Ceburnis1, J. Ovadnevaite1, G. Martucci1, J. Bialek1, C. Monahan1, M. Rinaldi2, M. C. Facchini2, H. Berresheim1, D. R. Worsnop3,4 and C. D. O'Dowd1 1School of Physics & Centre for Climate and Air Pollution Studies, National University of Ireland Galway, University Road, Galway, Ireland 2Institute of Atmospheric Sciences and Climate, National Research Council, Bologna, 20129, Italy. 3 Aerodyne Research, Inc., 45 Manning Road, Billerica, MA 01821-3976, USA 4 Physics Department, University of Helsinki, P.O. Box 64, 00014, Helsinki, Finland Organic matter has been observed to significantly contribute to particulate matter in every environment including pristine remote oceans. A significant if not dominant contribution of insoluble organic matter to marine aerosol has been proved to be of biogenic origin1,2. High time resolution measurements of marine organic matter have demonstrated a dynamic system with regular organic matter plume events occurring during summer3 as well as frequent open ocean particle formation events4. High-time resolution measurements of primary marine organic sea-spray physico-chemical properties reveal an apparent dichotomous behavior in terms of water uptake: specifically sea-spray aerosol enriched in organic matter possesses a low hygroscopic Growth Factor (GF~1.25) while simultaneously having a cloud condensation nucleus/condensation nuclei (CCN/CN) activation efficiency of between 83% at 0.25% supersaturation and 100% at 0.75%5. Simultaneous retrieval of Cloud Droplet Number Concentration (CDNC) during primary organic aerosol plumes reveal CDNC concentrations of 350 cm-3 in newly formed marine stratocumulus cloud for boundary layer organic mass concentrations of 3-4 ug m-36. It is suggested that marine hydrogels are responsible for this dichotomous behavior which has profound impacts to aerosol-cloud-climate system along with a better understood process analysis of aerosol formation by sea-spray7. A hydrophobic character of organic matter dominated aerosol in sub-saturated conditions should have significant implications for direct radiative effect while effectively forming cloud condensation nuclei should have significant contribution to indirect effect. 1 O'Dowd, C. D. et al. Nature 431, 676-680, doi:10.1038/Nature02959 (2004). 2 Ceburnis, D. et al. Atmos. Chem. Phys. Discuss. 11, 2749-2772, doi:doi:10.5194/acpd-11-2749-2011 (2011). 3 Ovadnevaite, J. et al. Geophys Res Lett 38, L02807, doi:10.1029/2010gl046083 (2011). 4 O'Dowd, C., et al. Geophys Res Lett 37, doi:L19805 10.1029/2010gl044679 (2010). 5 Ovadnevaite, J. et al. Geophys Res Lett (2011). 6 Martucci, G. and O'Dowd, C. D. Atmos. Meas. Tech. Discuss., 4, 4825-4865, doi:10.5194/amtd-4-4825-2011 (2011) 7 Gantt, B. et al. Atmos. Chem. Phys. Discuss. 11, 10525-10555, doi:10.5194/acpd-11-10525-2011 (2011).

  16. Evaluation of TransTech joint maker and precompaction screed.

    DOT National Transportation Integrated Search

    2000-09-01

    The primary objective of this evaluation is to determine the effectiveness of the Joint Maker and Precompaction : Screed, both developed by TransTech Systems, Inc., in achieving higher and more uniform density across the mat of : a rehabilitated Hot ...

  17. Green Power Partnership Top 30 Tech & Telecom

    EPA Pesticide Factsheets

    The U.S. EPA's Green Power Partnership is a voluntary program designed to reduce the environmental impact of electricity generation by promoting renewable energy. On this list are the largest green power users among tech and telecom partners within the GPP

  18. LASER Tech Briefs, September 1993. Volume 1, No. 1

    NASA Technical Reports Server (NTRS)

    Schnirring, Bill (Editor)

    1993-01-01

    This edition of LASER Tech briefs contains a feature on photonics. The other topics include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Computer Programs, Mechanics, Machinery, Fabrication Technology, Mathematics and Information Sciences, Life Sciences and books and reports.

  19. National Tech Prep Conference Review--Best Practices for Changing Times.

    ERIC Educational Resources Information Center

    Vandenberg, Victoria

    1995-01-01

    Provides an overview of the National Tech Prep Network Annual Conference in Atlanta, Georgia, October 5-7, 1995. Issues addressed include changes in funding for vocational education, new block grants, marketing programs, partnerships, and school to work. (JOW)

  20. Considering High-Tech Exhibits?

    ERIC Educational Resources Information Center

    Routman, Emily

    1994-01-01

    Discusses a variety of high-tech exhibit media used in The Living World, an educational facility operated by The Saint Louis Zoo. Considers the strengths and weaknesses of holograms, video, animatronics, video-equipped microscopes, and computer interactives. Computer interactives are treated with special attention. (LZ)

  1. NASA Tech Briefs, September 1995. Volume 19, No. 9

    NASA Technical Reports Server (NTRS)

    1995-01-01

    A special focus for this issue is Sensors. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. A section of Laser Tech Briefs is included.

  2. NASA Tech Briefs, December 1995. Volume 19, No. 12

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Topics include: a special focus section on Bio/Medical technology, electronic components and circuits, electronic systems, physical sciences, materials, computer programs, mechanics, machinery, manufacturing/fabrication, mathematics and information sciences, book and reports, and a special section on Laser Tech Briefs.

  3. The performances of standard and ResMed masks during bag-valve-mask ventilation.

    PubMed

    Lee, Hyoung Youn; Jeung, Kyung Woon; Lee, Byung Kook; Lee, Seung Joon; Jung, Yong Hun; Lee, Geo Sung; Min, Yong Il; Heo, Tag

    2013-01-01

    A tight mask seal is frequently difficult to obtain and maintain during single-rescuer bag-valve-mask (BVM) ventilation. The ResMed mask (Bella Vista, NSW, Australia) is a continuous-positive-airway-pressure mask (CM) designed for noninvasive ventilation. In this study, we compared the ventilation performances of a standard mask (SM) and a ResMed CM using a simulation manikin in an out-of-hospital single-rescuer BVM ventilation scenario. Thirty emergency medical technicians (EMTs) performed two 2-minute attempts to ventilate a simulation manikin using BVM ventilation, alternatively, with the SM or the ResMed CM in a randomized order. Ventilation parameters including tidal volume and peak airway pressure were measured using computer analysis software connected to the simulation manikin. Successful volume delivery was defined as delivery of 440-540 mL of tidal volume in accord with present cardiopulmonary resuscitation guidelines. BVM ventilation using the ResMed CM produced higher mean (± standard deviation) tidal volumes (452 ± 50 mL vs. 394 ± 113 mL, p = 0.014) and had a higher proportion of successful volume deliveries (65.3% vs. 26.7%, p < 0.001) than that using the SM. Peak airway pressure was higher in BVM ventilation using the ResMed CM (p = 0.035). Stomach insufflation did not occur during either method. Twenty-nine of the participants (96.7%) preferred BVM ventilation using the ResMed CM. BVM ventilations using ResMed CM resulted in a significantly higher proportion of successful volume deliveries meeting the currently recommended range of tidal volume. Clinical studies are needed to determine the value of the ResMed CM for BVM ventilation.

  4. Resveratrol Improves the Mitochondrial Function and Fertilization Outcome of Bovine Oocytes

    PubMed Central

    TAKEO, Shun; SATO, Daichi; KIMURA, Koji; MONJI, Yasunori; KUWAYAMA, Takehito; KAWAHARA-MIKI, Ryoka; IWATA, Hisataka

    2013-01-01

    The aim of the present study was to address the effect of resveratrol-mediated upregulation of sirtuin 1 (SIRT1) during oocyte maturation on mitochondrial function, the developmental ability of oocytes and on mechanisms responsible for blockage of polyspermic fertilization. Oocytes collected from slaughterhouse-derived ovaries were cultured in TCM-199 medium supplemented with 10% FCS and 0 or 20 µM resveratrol (Res). We examined the effect of Res on SIRT1 expression in in vitro-matured oocytes (Exp 1); fertilization and developmental ability (Exp 2); mitochondrial DNA copy number (Mt number), ATP content and mitochondrial membrane potential in matured oocytes (Exp 3); and the time required for proteinase to dissolve the zona pellucida following in vitro fertilization (as a marker of zona pellucida hardening), as well as on the distribution of cortical granules before and after fertilization (Exp 4). In Exp 1, the 20 µM Res treatment upregulated protein expression of SIRT1 in oocytes. In Exp 2, Res treatment improved the ratio of normal fertilization and the total cell number of blastocysts. In Exp 3, Res treatment significantly increased the ATP content in matured oocytes. Additionally, Res increased the overall Mt number and mitochondrial membrane potential, but the effect was donor-dependent. In Exp 4, Res-induced zona hardening improved the distribution and exocytosis of cortical granules after in vitro fertilization. In conclusion, Res improved the quality of oocytes by improving mitochondrial quantity and quality. In addition, Res added to the maturation medium enhanced SIRT1 protein expression in oocytes and improved fertilization via reinforcement of the mechanisms responsible for blockage of polyspermic fertilization. PMID:24390595

  5. Development of renewable energy in China: Studying the experience and making recommendations for Russia

    NASA Astrophysics Data System (ADS)

    Lanshina, T. A.; Kulakov, A. V.

    2017-07-01

    The article reviews a state policy of China, due to which the country has managed to develop the world's largest sector of renewable energy sources (RES). Basic aspects of the formation and development of a comprehensive system of state support for the sector, i.e., the creation of scientific and technological advancement, stimulation of renewable energy equipment manufacturing, and support for RES electricity generation, are studied. Key programs implemented in specific stages are analyzed. Considerable attention is paid to the role and characteristics of foreign technology transfers. The dynamics of China's RES sector and the results of its rapid growth with the active participation of the state are researched. On the basis of the analysis, it is concluded that, in general, China's experience in development of RES is successful. Using the example of China, it is safe to say that, in the presence of a balanced state policy, a country is able to create in a decade a strong renewable energy equipment industry and to become a leader in the area of RES electricity generation. Specific features and main problems of the Russian RES sector are considered. On the basis of China's experience, recommendations for improving the state policy in RES are made for Russia. According to the authors, first of all, a sharp increase in state support for scientific research and development (R&D), pilot and demonstration projects, recognition of RES as a part of the fuel and energy sector at all tiers of authority, guarantees of state support for RES in the long run, ensuring access to long-term funds, and the creation of state programs supporting households participation in the distributed power generation are needed.

  6. SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy.

    PubMed

    Cappetta, Donato; Esposito, Grazia; Piegari, Elena; Russo, Rosa; Ciuffreda, Loreta Pia; Rivellino, Alessia; Berrino, Liberato; Rossi, Francesco; De Angelis, Antonella; Urbanek, Konrad

    2016-02-15

    Doxorubicin (DOXO) is an effective anti-neoplastic drug but its clinical benefits are hampered by cardiotoxicity. Oxidative stress, apoptosis and myocardial fibrosis mediate the anthracycline cardiomyopathy. ROS trigger TGF-β pathway that activates cardiac fibroblasts promoting fibrosis. Myocardial stiffness contributes to diastolic dysfunction, less studied aspect of anthracycline cardiomyopathy. Considering the role of SIRT1 in the inhibition of the TGF-β/SMAD3 pathway, resveratrol (RES), a SIRT1 activator, might improve cardiac function by interfering with the development of cardiac fibrosis in a model of DOXO-induced cardiomyopathy. F344 rats received a cumulative dose of 15 mg/kg of DOXO in 2 weeks or DOXO+RES (DOXO and RES, 2.5mg/kg/day, concomitantly for 2 weeks and then RES alone for 1 more week). The effects of RES on cardiac fibroblasts were also tested in vitro. Along with systolic dysfunction, DOXO was also responsible of diastolic abnormalities. Myocardial stiffness correlated with fibroblast activation and collagen deposition. DOXO+RES co-treatment significantly improved ± dP/dt and, more interestingly, ameliorated end-diastolic pressure/volume relationship. Treatment with RES resulted in reduced fibrosis and fibroblast activation and, most importantly, the mortality rate was significantly reduced in DOXO+RES group. Fibroblasts isolated from DOXO+RES-treated rats, in which SIRT1 was upregulated, showed decreased levels of TGF-β and pSMAD3/SMAD3 when compared to cells isolated from DOXO-exposed hearts. Our findings reveal a key role of SIRT1 in supporting animal survival and functional parameters of the heart. SIRT1 activation by interfering with fibrogenesis can improve relaxation properties of myocardium and attenuate myocardial remodeling related to chemotherapy. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  7. Transferring Technology to Industry

    NASA Technical Reports Server (NTRS)

    Wolfenbarger, J. Ken

    2006-01-01

    This slide presentation reviews the technology transfer processes in which JPL has been involved to assist in transferring the technology derived from aerospace research and development to industry. California Institute of Technology (CalTech), the organization that runs JPL, is the leading institute in patents for all U.S. universities. There are several mechanisms that are available to JPL to inform industry of these technological advances: (1) a dedicated organization at JPL, National Space Technology Applications (NSTA), (2) Tech Brief Magazine, (3) Spinoff magazine, and (4) JPL publications. There have also been many start-up organizations and businesses from CalTech.

  8. Memory function and supportive technology

    PubMed Central

    Charness, Neil; Best, Ryan; Souders, Dustin

    2013-01-01

    Episodic and working memory processes show pronounced age-related decline, with other memory processes such as semantic, procedural, and metamemory less affected. Older adults tend to complain the most about prospective and retrospective memory failures. We introduce a framework for deciding how to mitigate memory decline using augmentation and substitution and discuss techniques that change the user, through mnemonics training, and change the tool or environment, by providing environmental support. We provide examples of low-tech and high-tech memory supports and discuss constraints on the utility of high-tech systems including effectiveness of devices, attitudes toward memory aids, and reliability of systems. PMID:24379752

  9. Environmental Impact Research Program. Proceedings of the US Army Corps of Engineers Riparian Zone Restoration and Management Workshop Held in San Antonio, Texas on 24-27 February 1986

    DTIC Science & Technology

    1988-02-01

    Dwayne G. Lee, CE, was Commander and Director of WES. Dr. Robert W. Whalin was Technical Director. This report should be cited as follows: Martin, Chester...Environmental features for streambank protection projects. U.S. Army Eng. Waterways Exp. Sta., Tech. Rep. E-84-11. 150 pp. Johnson , R. R., and D. A. Jones...Serv. Gen. Tech. Rep. RM-43. 217 pp. 57 Johnson , R. R., and J. F. McCormick (tech. coords.). 1978. Strategies for protection and management of

  10. Exploring cognitive support use and preference by college students with TBI: A mixed-methods study.

    PubMed

    Brown, Jessica; Hux, Karen; Hey, Morgan; Murphy, Madeline

    2017-01-01

    Many college students with TBI rely on external strategies and supports to compensate for persistent memory, organization, and planning deficits that interfere with recalling and executing daily tasks. Practitioners know little, however, about the supports students with TBI choose for this purpose, the reasoning behind their choice, or preferred features of selected supports. The purpose of this study was to explore these issues. We collected and analyzed quantitative and qualitative data from eight college students with TBI for completion of a concurrent triangulation mixed-methods design. Data analysis included evaluation and triangulation of participant demographic information, survey responses about persistent post-injury symptoms, transcripts from semi-structured interviews about cognitive support devices and strategies, and ranking results about specific compensatory tools. Results suggest that college students with TBI prefer high-tech external supports-sometimes with the addition of low-tech, paper supports-to assist them in managing daily tasks. This preference related to features of portability, accessibility, and automatic reminders. An electronic calendar was the most-preferred high-tech support, and a paper checklist was the most-preferred low-tech support. Rehabilitation professionals should consider implementing high-tech supports with preferred characteristics during treatment given the preferences of students with TBI and the consequent likelihood of their continued long-term use following reintegration to community settings.

  11. Project Synopsis for High School/High Tech

    NASA Technical Reports Server (NTRS)

    1997-01-01

    To help increase the diversity of workers at NASA centers it is necessary to provide students with disabilities the opportunities to explore careers in high technology. HIGH SCHOOL/HIGH TECH, an enrichment program, pioneered at Goddard Space Flight Center, successfully introduces students with disabilities to high tech careers. This community-based partnership serves as a model for three additional NASA sites-Ames Research Center, Johnson Space Flight Center, and Lewis Research Center. For a three year period beginning August 15, 1995, provide financial and technical support to a local agency in each NASA center area which serves persons with disabilities to enable a High School/High Tech program to develop and stand alone. Each project will develop a basis of cooperation with Ames, Johnson, and Lewis as well as a variety of community groups including the public schools, high tech employers, post-secondary education and training programs, rehabilitation agencies, and community economic development organizations. Throughout the startup period and thereafter, local youths with disabilities will have early exposure to professions in mathematics, science, and technology-related fields. This exposure will be multifaceted to insure adequate opportunity for realistic career exploration so these youths have an opportunity to test their interests and abilities. The exposure will be presented in the most supportive environment that is feasible.

  12. An optimal contract approach to hospital financing.

    PubMed

    Boadway, Robin; Marchand, Maurice; Sato, Motohiro

    2004-01-01

    Existing models of hospital financing advocate mixed schemes which include both lump-sum and cost-based payments. The doctor is generally the unique decision maker, which is unrealistic in a hospital setting where both managers and doctors are involved. This paper develops a model in which managers and doctors are responsible for different decisions within the hospital. In this model, public authorities who provide the financing, hospital managers who allocate resources within the hospital, and doctors who assign patients to either a low-tech or a high-tech therapy have information of increasing quality on the casemix of patients. The public authorities sign with hospital managers contracts specifying some lump-sum financing and some size of a high-tech equipment. In turn, managers, who know the broad mix of patients in the hospital, sign with hospital doctors contracts that specify the non-medical resources allocated to this facility as well as some remuneration. Doctors, who know each patient's illness severity, select the patients to be treated by the high-tech facility, and receive from public authorities some fee-for-service payment that is differentiated according to the low- or high-tech treatment used for curing their patients. What emerges is a two-stage agency problem in which contracts are designed to elicit information in the most efficient way.

  13. The impacts of renewable energy policies on renewable energy sources for electricity generating capacity

    NASA Astrophysics Data System (ADS)

    Koo, Bryan Bonsuk

    Electricity generation from non-hydro renewable sources has increased rapidly in the last decade. For example, Renewable Energy Sources for Electricity (RES-E) generating capacity in the U.S. almost doubled for the last three year from 2009 to 2012. Multiple papers point out that RES-E policies implemented by state governments play a crucial role in increasing RES-E generation or capacity. This study examines the effects of state RES-E policies on state RES-E generating capacity, using a fixed effects model. The research employs panel data from the 50 states and the District of Columbia, for the period 1990 to 2011, and uses a two-stage approach to control endogeneity embedded in the policies adopted by state governments, and a Prais-Winsten estimator to fix any autocorrelation in the panel data. The analysis finds that Renewable Portfolio Standards (RPS) and Net-metering are significantly and positively associated with RES-E generating capacity, but neither Public Benefit Funds nor the Mandatory Green Power Option has a statistically significant relation to RES-E generating capacity. Results of the two-stage model are quite different from models which do not employ predicted policy variables. Analysis using non-predicted variables finds that RPS and Net-metering policy are statistically insignificant and negatively associated with RES-E generating capacity. On the other hand, Green Energy Purchasing policy is insignificant in the two-stage model, but significant in the model without predicted values.

  14. Bone metabolic responses to low energy availability achieved by diet or exercise in active eumenorrheic women.

    PubMed

    Papageorgiou, Maria; Martin, Daniel; Colgan, Hannah; Cooper, Simon; Greeves, Julie P; Tang, Jonathan C Y; Fraser, William D; Elliott-Sale, Kirsty J; Sale, Craig

    2018-06-19

    We aimed to explore the effects of low energy availability (EA)[15 kcal·kg lean body mass (LBM) -1 ·d -1 ] achieved by diet or exercise on bone turnover markers in active, eumenorrheic women. By using a crossover design, ten eumenorrheic women (VO 2 peak : 48.1 ± 3.3 ml·kg -1 ·min -1 ) completed all three, 3-day conditions in a randomised order: controlled EA (CON; 45 kcal·kgLBM -1 ·d -1 ), low EA through dietary energy restriction (D-RES; 15 kcal·kgLBM -1 ·d -1 ) and low EA through increasing exercise energy expenditure (E-RES; 15 kcal·kgLBM -1 ·d -1 ), during the follicular phase of three menstrual cycles. In CON, D-RES and E-RES, participants consumed diets providing 45, 15 and 45 kcal·kgLBM -1 ·d -1 . In E-RES only, participants completed supervised running sessions (129 ± 10 min·d -1 ) at 70% of their VO 2 peak that resulted in an exercise energy expenditure of 30 kcal·kg LBM -1 ·d -1 . Blood samples were collected at baseline (BASE) and at the end of the 3-day period (D6) and analysed for bone turnover markers (β-CTX and P1NP), markers of calcium metabolism (PTH, albumin-adjusted Ca, Mg and PO 4 ) and hormones (IGF-1, T 3 , insulin, leptin and 17β-oestradiol). In D-RES, P1NP concentrations at D6 decreased by 17% (BASE: 54.8 ± 12.7 μg·L -1 , D6: 45.2 ± 9.3 μg·L -1 , P < 0.001, d = 0.91) and were lower than D6 concentrations in CON (D6: 52.5 ± 11.9 μg·L -1 , P = 0.001). P1NP did not change significantly in E-RES (BASE: 55.3 ± 14.4 μg·L -1 , D6: 50.9 ± 15.8 μg·L -1 , P = 0.14). β-CTX concentrations did not change following D-RES (BASE: 0.48 ± 0.18 μg·L -1 , D6: 0.55 ± 0.17 μg·L -1 ) or E-RES (BASE: 0.47 ± 0.24 μg·L -1 , D6: 0.49 ± 0.18 μg·L -1 ) (condition × time interaction effect, P = 0.17). There were no significant differences in P1NP (P = 0.25) or β-CTX (P = 0.13) responses between D-RES and E-RES. Both conditions resulted in reductions in IGF-1 (-13% and - 23% from BASE in D-RES and E-RES, both P < 0.01) and leptin (-59% and - 61% from BASE in D-RES and E-RES, both P < 0.001); T 3 decreased in D-RES only (-15% from BASE, P = 0.002) and PO 4 concentrations decreased in E-RES only (-9%, P = 0.03). Low EA achieved through dietary energy restriction resulted in a significant decrease in bone formation but no change in bone resorption, whereas low EA achieved through exercise energy expenditure did not significantly influence bone metabolism. Both low EA conditions elicited significant and similar changes in hormone concentrations. Copyright © 2018. Published by Elsevier Inc.

  15. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile covers these occupations: manufacturing technician, computer-assisted design and drafting (CADD) technician, quality technician, and mechanical technician. Section 1 provides occupation definitions. Section 2 lists development committee members. Section 3 provides the leveling codes---abbreviations for grade level…

  16. High Tech Educators Network Evaluation.

    ERIC Educational Resources Information Center

    O'Shea, Dan

    A process evaluation was conducted to assess the High Tech Educators Network's (HTEN's) activities. Four basic components to the evaluation approach were documentation review, program logic model, written survey, and participant interviews. The model mapped the basic goals and objectives, assumptions, activities, outcome expectations, and…

  17. NASA Tech Briefs, October 1998. Volume 22, No. 10

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage sections on sensors/imaging and mechanical technology, and sections on electronic components and circuits, electronic systems, software, materials, machinery/automation, manufacturing/fabrication, physical sciences, information sciences, book and reports, and a special section of Photonics Tech Briefs.

  18. The Virginia Tech Library System (VTLS).

    ERIC Educational Resources Information Center

    McGrath, Deborah Hall; Lee, Carl R.

    1989-01-01

    Discusses topics relating to the Virginia Tech Library System: the company (VTLS, Inc.); the software; data structure; cataloging, status, and authority control; circulation; serials control and acquisitions; the online catalog; management reporting; networking; and the operating environment. Sidebars discuss the Vanilla Network; LINNEA--a network…

  19. APPLICATION ANALYSIS REPORT: THE DEHYDRO-TECH CORPORATION CARVER-GREENFIELD PROCESS

    EPA Science Inventory

    This report evaluates the Dehydro-Tech Corporation's Carver-Greenfield (C-G) Process and focuses on the technology’s ability to separate waste mixtures into their constituent solid, organic, and water fractions while producing a solid residual that meets applicable disposal requi...

  20. High-Tech Security Help.

    ERIC Educational Resources Information Center

    Flanigan, Robin L.

    2000-01-01

    Advocates embrace high-tech security measures as necessary to avoid Columbine-style massacres. Critics contend that school systems can go overboard, making students feel less safe and too closely scrutinized. Current electronic, biometric, and computer-mapping devices and school applications are discussed. Vendors are listed. (MLH)

  1. Long-term evaluation of Astra Tech and Brånemark implants in patients treated with full-arch bridges. Results after 12-15 years.

    PubMed

    Ravald, Nils; Dahlgren, Simon; Teiwik, Anders; Gröndahl, Kerstin

    2013-10-01

    To study the long-term outcome of implant survival rate, soft and hard tissue conditions and prosthetic status in a group of individuals treated with either Astra Tech TiOblast or Brånemark turned implants supporting a full-arch bridge. Edentulous patients treated with either Astra Tech TiOblast surface or Brånemark turned implants were recalled for examination after 12-15 years. Out of initially 66 patients 46 were available for examination. Intra-oral radiographs were taken for bone level assessments. Clinical prosthetic conditions, number of surviving implants, implant stability, plaque scores, probing pocket depths, bleeding and pus after probing were recorded. Analyses of bone level changes during the total observation period were performed. Three patients in the Astra Tech group lost totally eight implants and five patients in the Brånemark group lost 10 implants during the total observation period. No statistically significant difference in implant loss or bone level change was found. Sixteen per cent of Astra Tech and 29% of Brånemark patients showed at least one implant with ≥2 mm bone loss after the first year in function. The corresponding prevalence on implant level was 6% and 5% respectively. No significant differences were found between the other examined variables. Two patients showed prosthetic complications of the supra construction in need of repair. Seven bridges had minor ceramic chippings. Treatment with Astra Tech TiOblast implants and Brånemark turned implants supporting full-arch bridges showed generally good clinical results with low numbers of implants with marginal bone loss indicative of peri-implantitis. No significant differences were found between the implant systems after 12-15 years in function. © 2012 John Wiley & Sons A/S.

  2. RES-E Support Policies In The Baltic States: Development Aspect (Part I)

    NASA Astrophysics Data System (ADS)

    Bobinaite, V.; Priedite, I.

    2015-02-01

    Despite quite similar conditions (natural resources) for electricity production from renewable energy sources (RES-E) in three Baltic States (Estonia, Latvia and Lithuania), significant differences exist in these countries as to the RES-E production volume. In Latvia this volume is the highest, while in Estonia and Lithuania it is half as high. One of the factors that determine the RES-E production volumes is support policies, which in the Baltic States are different. The main objective of this work was to analyze and compare these support policies. The results have shown that for rapid RES-E development the most effective policy is to be market-oriented (as in Estonia), whereas for more stable development such policy should be producer-oriented (as in Lithuania).

  3. Resveratrol cocrystals with enhanced solubility and tabletability.

    PubMed

    Zhou, Zhengzheng; Li, Wanying; Sun, Wei-Jhe; Lu, Tongbu; Tong, Henry H Y; Sun, Changquan Calvin; Zheng, Ying

    2016-07-25

    Two new 1:1 cocrystals of resveratrol (RES) with 4-aminobenzamide (RES-4ABZ) and isoniazid (RES-ISN) were synthesized by liquid assisted grinding (LAG) and rapid solvent removal (RSR) methods using ethanol as solvent. Their physiochemical properties were characterized using PXRD, DSC, solid state and solution NMR, FT-IR, and HPLC. Pharmaceutically relevant properties, including tabletability, solubility, intrinsic dissolution rate, and hygroscopicity, were evaluated. Temperature-composition phase diagram for RES-ISN cocrystal system was constructed from DSC data. Both cocrystals show higher solubility than resveratrol over a broad range of pH. They are phase stable and non-hygroscopic even under high humidity conditions. Importantly, both cocrystals exhibit improved solubility and tabletability compared with RES, which make them more suitable candidates for tablet formulation development. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. The wheat Lr34 multipathogen resistance gene confers resistance to anthracnose and rust in sorghum.

    PubMed

    Schnippenkoetter, Wendelin; Lo, Clive; Liu, Guoquan; Dibley, Katherine; Chan, Wai Lung; White, Jodie; Milne, Ricky; Zwart, Alexander; Kwong, Eunjung; Keller, Beat; Godwin, Ian; Krattinger, Simon G; Lagudah, Evans

    2017-11-01

    The ability of the wheat Lr34 multipathogen resistance gene (Lr34res) to function across a wide taxonomic boundary was investigated in transgenic Sorghum bicolor. Increased resistance to sorghum rust and anthracnose disease symptoms following infection with the biotrophic pathogen Puccinia purpurea and the hemibiotroph Colletotrichum sublineolum, respectively, occurred in transgenic plants expressing the Lr34res ABC transporter. Transgenic sorghum lines that highly expressed the wheat Lr34res gene exhibited immunity to sorghum rust compared to the low-expressing single copy Lr34res genotype that conferred partial resistance. Pathogen-induced pigmentation mediated by flavonoid phytoalexins was evident on transgenic sorghum leaves following P. purpurea infection within 24-72 h, which paralleled Lr34res gene expression. Elevated expression of flavone synthase II, flavanone 4-reductase and dihydroflavonol reductase genes which control the biosynthesis of flavonoid phytoalexins characterized the highly expressing Lr34res transgenic lines 24-h post-inoculation with P. purpurea. Metabolite analysis of mesocotyls infected with C. sublineolum showed increased levels of 3-deoxyanthocyanidin metabolites were associated with Lr34res expression, concomitant with reduced symptoms of anthracnose. © 2017 The Authors. Plant Biotechnology Journal published by Society for Experimental Biology and The Association of Applied Biologists and John Wiley & Sons Ltd.

  5. Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

    PubMed Central

    Caughey, Winslow S.; Raymond, Lynne D.; Horiuchi, Motohiro; Caughey, Byron

    1998-01-01

    A central aspect of pathogenesis in the transmissible spongiform encephalopathies or prion diseases is the conversion of normal protease-sensitive prion protein (PrP-sen) to the abnormal protease-resistant form, PrP-res. Here we identify porphyrins and phthalocyanines as inhibitors of PrP-res accumulation. The most potent of these tetrapyrroles had IC50 values of 0.5–1 μM in scrapie-infected mouse neuroblastoma (ScNB) cell cultures. Inhibition was observed without effects on protein biosynthesis in general or PrP-sen biosynthesis in particular. Tetrapyrroles also inhibited PrP-res formation in a cell-free reaction composed predominantly of hamster PrP-res and PrP-sen. Inhibitors were found among phthalocyanines, deuteroporphyrins IX, and meso-substituted porphines; examples included compounds containing anionic, neutral protic, and cationic peripheral substituents and various metals. We conclude that certain tetrapyrroles specifically inhibit the conversion of PrP-sen to PrP-res without apparent cytotoxic effects. The inhibition observed in the cell-free conversion reaction suggests that the mechanism involved direct interactions of the tetrapyrrole with PrP-res and/or PrP-sen. These findings introduce a new class of inhibitors of PrP-res formation that represents a potential source of therapeutic agents for transmissible spongiform encephalopathies. PMID:9770449

  6. Complement inhibition prevents gut ischemia and endothelial cell dysfunction after hemorrhage/resuscitation.

    PubMed

    Fruchterman, T M; Spain, D A; Wilson, M A; Harris, P D; Garrison, R N

    1998-10-01

    Complement, a nonspecific immune response, is activated during hemorrhage/resuscitation (HEM/RES) and is involved in cellular damage. We hypothesized that activated complement injures endothelial cells (ETCs) and is responsible for intestinal microvascular hypoperfusion after HEM/RES. Four groups of rats were studied by in vivo videomicroscopy of the intestine: SHAM, HEM/RES, HEM/RES + sCR1 (complement inhibitor, 15 mg/kg intravenously given before resuscitation), and SHAM + sCR1. Hemorrhage was to 50% of mean arterial pressure for 60 minutes followed by resuscitation with shed blood plus an equal volume of saline. ETC function was assessed by response to acetylcholine. Resuscitation restored central hemodynamics to baseline after hemorrhage. After resuscitation, inflow A1 and premucosal A3 arterioles progressively constricted (-24% and -29% change from baseline, respectively), mucosal blood flow was reduced, and ETC function was impaired. Complement inhibition prevented postresuscitation vasoconstriction and gut ischemia. This protective effect appeared to involve preservation of ETC function in the A3 vessels (SHAM 76% of maximal dilation, HEM/RES 61%, HEM/RES + sCR1 74%, P < .05). Complement inhibition preserved ETC function after HEM/RES and maintained gut perfusion. Inhibition of complement activation before resuscitation may be a useful adjunct in patients experiencing major hemorrhage and might prevent the sequelae of gut ischemia.

  7. Postactivation Potentiation Following Acute Bouts of Plyometric versus Heavy-Resistance Exercise in Collegiate Soccer Players.

    PubMed

    Sharma, Sourabh Kumar; Raza, Shahid; Moiz, Jamal Ali; Verma, Shalini; Naqvi, Irshad Husain; Anwer, Shahnawaz; Alghadir, Ahmad H

    2018-01-01

    Postactivation potentiation is referred to as an acute and temporary enhancement of muscle performance resulting from previous muscle contraction. The purpose of this study was to compare the acute effect of plyometric exercise (PLY) and heavy-resistance exercise (RES) on the blood lactate level (BLa) and physical performance. Fourteen male collegiate soccer players were randomized to perform either RES or PLY first and then crossed over to perform the opposite intervention. PLY consisted of 40 jumps, whereas RES comprised ten single repetitions at 90% of one repetition maximum. BLa and physical performance (countermovement jump height and 20-m sprint) were measured before and at 1 and 10 min following the exercise. No significant difference was observed in the BLa for both exercises (PLY and RES). Relative to baseline, countermovement jump (CMJ) height was significantly better for the PLY group after 1 min ( P = 0.004) and after 10 min ( P = 0.001) compared to that of the RES group. The 20-m sprint time was significantly better for PLY at 10 min ( P = 0.003) compared to that of RES. The present study concluded that, compared to RES, PLY causes greater potentiation, which leads to improved physical performance. This trial is registered with NCT03150277.

  8. Collaborative decision-making on wind power projects based on AHP method

    NASA Astrophysics Data System (ADS)

    Badea, A.; Proştean, G.; Tămăşilă, M.; Vârtosu, A.

    2017-01-01

    The complexity of projects implementation in Renewable Energy Sources (RES) requires finding collaborative alliances between suppliers and project developers in RES. Links activities in supply chain in RES, respectively, transportation of heavy components, processing orders to purchase quality raw materials, storage and materials handling, packaging, and other complex activities requiring a logistics system collaboratively to be permanently dimensioned properly selected and monitored. Requirements imposed by stringency of wind power energy projects implementation inevitably involves constraints in infrastructure, implementation and logistics. Thus, following an extensive research in RES project, to eliminate these constraints were identified alternative collaboration to provide feasible solutions on different levels of performance. The paper presents a critical analysis of different collaboration alternatives in supply chain for RES projects, selecting the ones most suitable for particular situations by using decision-making method Analytic Hierarchy Process (AHP). The role of AHP method was to formulate a decision model by which can be establish the collaboration alternative choice through mathematical calculation to reduce the impact created by constraints encountered. The solution provided through AHP provides a framework for detecting optimal alternative collaboration between suppliers and project developers in RES and avoids some breaks in the chain by resizing safety buffers for leveling orders in RES projects.

  9. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile for computer-integrated manufacturing technology begins with definitions for four occupations: manufacturing technician, quality technician, mechanical engineering technician, and computer-assisted design/drafting (CADD) technician. A chart lists competencies by unit and indicates whether entire or partial unit is…

  10. TECH-NJ, 2000-2002.

    ERIC Educational Resources Information Center

    Dell, Amy G., Ed.

    2002-01-01

    These three issues of "TECH-NJ" from 2000 to 2002 focus on technology and children with disabilities in New Jersey. The issues address how technology can support language development and people with learning disabilities, and technology tools that support reading. Featured articles include: (1) "Adaptive Technology Center for New…

  11. NASA Tech Briefs, December 2001. Volume 25, No. 12

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Topics include: special coverage section on sensors, and sections on electronic components and systems, software, materials, mechanics, information sciences, book and reports, and a special section of Motion Control Tech Briefs. It also contains a section celebrating the 25th anniversary of the publication.

  12. Tech Transfer News. Volume 9, No. 1

    NASA Technical Reports Server (NTRS)

    Victor, Megan E. (Compiler)

    2017-01-01

    Kennedy Tech Transfer News is the magazine of the Technology Transfer Office at NASA's Kennedy Space Center, Florida. This magazine seeks to inform and educate civil servant and contractor personnel at Kennedy Space Center about actively participating in achieving NASA's technology transfer and partnership goals.

  13. Horticulture. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Ohio State Univ., Wooster. Agricultural Technical Inst.

    This tech prep competency profile (TCP), which was developed by a consortium of Ohio educators and business/industry representatives, lists the competencies that have been identified as necessary for employment in the following occupations: nursery technician; golf course superintendent; landscape designer/manager; lawn care specialist; tree care…

  14. Reports show fewer pallets entering landfills

    Treesearch

    Robert J. Bush; Philip A. Araman

    2010-01-01

    Information from a series of Virginia Tech studies reveals current trends in core utilization by the pallet industry. The most recent report released this year studied trends from 2006. Virginia Tech researchers compared these results to five previous studies going all the way back to 1992.

  15. Tech Gets Physical

    ERIC Educational Resources Information Center

    Ravage, Barbara

    2011-01-01

    As colleges push for increased efficiencies, facilities departments nationwide are turning more and more to high-tech approaches. Nowhere has this trend been more visible than in the realm of energy consumption, where managers hope to extract significant cost savings. Technology is helping facilities managers achieve significant efficiencies,…

  16. Alcohol and highway safety : a special report on race/ethnicity and impaired driving : traffic tech.

    DOT National Transportation Integrated Search

    2010-11-01

    The report examined in this edition of "Traffic Tech" reviews the state of knowledge of alcohol-impaired : driving among major racial and ethnic groups : living in the United States. Although it primarily focuses : on the relationship between impaire...

  17. Assessing segment- and corridor-based travel-time reliability on urban freeways tech transfer summary : tech transfer summary.

    DOT National Transportation Integrated Search

    2016-09-01

    Travel time and travel-time reliability have been used as performance : measures to evaluate traffic system conditions and develop advanced : traveler information and traffic management systems. The objectives of this research were to: : - Quantify s...

  18. National traffic speeds survey I: 2007 : traffic tech.

    DOT National Transportation Integrated Search

    2012-09-01

    The speed survey reviewed in this edition of "Traffic Tech" was designed as a geographic cluster : sample of primary sampling units (PSUs), which can be : a city, county, or group of two or three counties. PSUs : were chosen to represent a range of c...

  19. Guidelines for design and rating of gusset-plate connections for steel truss bridges : [tech brief].

    DOT National Transportation Integrated Search

    2014-08-01

    The FHWA guide provides rating guidance : on both load and resistance factor rating : (LRFR) and load factor rating philosophies. : Discussions in this TechBrief are from the LRFR : perspective only. The FHWA guide recommends five resistance checks a...

  20. Pricing and inventory policies for Hi-tech products under replacement warranty

    NASA Astrophysics Data System (ADS)

    Tsao, Yu-Chung; Teng, Wei-Guang; Chen, Ruey-Shii; Chou, Wang-Ying

    2014-06-01

    Companies, especially in the Hi-tech (high-technology) industry (such as computer, communication and consumer electronic products), often provide a replacement warranty period for purchased items. In reality, simultaneously determining the price and inventory decisions under warranty policy is an important issue. The objective of this paper is to develop a joint pricing and inventory model for Hi-tech products under replacement warranty policy. In the first model, we consider a Hi-tech product feature in which the selling price is declining in a trend. We determine the optimal inventory level for each period and retail price for the first period while maximising the total profit. In the second model, we further determine the optimal retail price and inventory level for each period in the dynamic demand market. This study develops solution approaches to solve the problems described above. Numerical analysis discusses the influence of system parameters on the company's decisions and behaviours. The results of this study could serve as a reference for business managers or administrators.

  1. TurboTech Technical Evaluation Automated System

    NASA Technical Reports Server (NTRS)

    Tiffany, Dorothy J.

    2009-01-01

    TurboTech software is a Web-based process that simplifies and semiautomates technical evaluation of NASA proposals for Contracting Officer's Technical Representatives (COTRs). At the time of this reporting, there have been no set standards or systems for training new COTRs in technical evaluations. This new process provides boilerplate text in response to interview style questions. This text is collected into a Microsoft Word document that can then be further edited to conform to specific cases. By providing technical language and a structured format, TurboTech allows the COTRs to concentrate more on the actual evaluation, and less on deciding what language would be most appropriate. Since the actual word choice is one of the more time-consuming parts of a COTRs job, this process should allow for an increase in quantity of proposals evaluated. TurboTech is applicable to composing technical evaluations of contractor proposals, task and delivery orders, change order modifications, requests for proposals, new work modifications, task assignments, as well as any changes to existing contracts.

  2. Fine-Filament MgB2 Superconductor Wire

    NASA Technical Reports Server (NTRS)

    Cantu, Sherrie

    2015-01-01

    Hyper Tech Research, Inc., has developed fine-filament magnesium diboride (MgB2) superconductor wire for motors and generators used in turboelectric aircraft propulsion systems. In Phase I of the project, Hyper Tech demonstrated that MgB2 multifilament wires (<10 micrometers) could reduce alternating current (AC) losses that occur due to hysteresis, eddy currents, and coupling losses. The company refined a manufacturing method that incorporates a magnesium-infiltration process and provides a tenfold enhancement in critical current density over wire made by a conventional method involving magnesium-boron powder mixtures. Hyper Tech also improved its wire-drawing capability to fabricate fine multifilament strands. In Phase II, the company developed, manufactured, and tested the wire for superconductor and engineering current density and AC losses. Hyper Tech also fabricated MgB2 rotor coil packs for a superconducting generator. The ultimate goal is to enable low-cost, round, lightweight, low-AC-loss superconductors for motor and generator stator coils operating at 25 K in next-generation turboelectric aircraft propulsion systems.

  3. Additive Transforms Paint into Insulation

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Tech Traders Inc. sought assistance developing low-cost, highly effective coatings and paints that created useful thermal reflectance and were safe and non-toxic. In cooperation with a group of engineers at Kennedy Space Center., Tech Traders created Insuladd, a powder additive made up of microscopic, inert gas-filled, ceramic microspheres that can be mixed into ordinary interior or exterior paint, allowing the paint to act like a layer of insulation. When the paint dries, this forms a radiant heat barrier, turning the ordinary house paint into heat-reflecting thermal paint. According to Tech Traders, the product works with all types of paints and coatings and will not change the coverage rate, application, or adhesion of the paint. Other useful applications include feed storage silos to help prevent feed spoilage, poultry hatcheries to reduce the summer heat and winter cold effects, and on military vehicles and ships. Tech Traders has continued its connection to the aerospace community by recently providing Lockheed Martin Corporation with one of its thermal products for use on the F-22 Raptor.

  4. Detecting Tsunami Source Energy and Scales from GNSS & Laboratory Experiments

    NASA Astrophysics Data System (ADS)

    Song, Y. T.; Yim, S. C.; Mohtat, A.

    2016-12-01

    Historically, tsunami warnings based on the earthquake magnitude have not been very accurate. According to the 2006 U.S. Government Accountability Office report, an unacceptable 75% false alarm rate has prevailed in the Pacific Ocean (GAO-06-519). One of the main reasons for those inaccurate warnings is that an earthquake's magnitude is not the scale or power of the resulting tsunami. For the last 10 years, we have been developing both theories and algorithms to detect tsunami source energy and scales, instead of earthquake magnitudes per se, directly from real-time Global Navigation Satellite System (GNSS) stations along coastlines for early warnings [Song 2007; Song et al., 2008; Song et al., 2012; Xu and Song 2013; Titov et al, 2016]. Here we will report recent progress on two fronts: 1) Examples of using GNSS in detecting the tsunami energy scales for the 2004 Sumatra M9.1 earthquake, the 2005 Nias M8.7 earthquake, the 2010 M8.8 Chilean earthquake, the 2011 M9.0 Tohoku-Oki earthquake, and the 2015 M8.3 Illapel earthquake. 2) New results from recent state-of-the-art wave-maker experiments and comparisons with GNSS data will also be presented. Related reference: Titov, V., Y. T. Song, L. Tang, E. N. Bernard, Y. Bar-Sever, and Y. Wei (2016), Consistent estimates of tsunami energy show promise for improved early warning, Pur Appl. Geophs., DOI: 10.1007/s00024-016-1312-1. Xu, Z. and Y. T. Song (2013), Combining the all-source Green's functions and the GPS-derived source for fast tsunami prediction - illustrated by the March 2011 Japan tsunami, J. Atmos. Oceanic Tech., jtechD1200201. Song, Y. T., I. Fukumori, C. K. Shum, and Y. Yi (2012), Merging tsunamis of the 2011 Tohoku-Oki earthquake detected over the open ocean, Geophys. Res. Lett., doi:10.1029/2011GL050767. Song, Y. T., L.-L. Fu, V. Zlotnicki, C. Ji, V. Hjorleifsdottir, C.K. Shum, and Y. Yi, 2008: The role of horizontal impulses of the faulting continental slope in generating the 26 December 2004 Tsunami (2007), Ocean Modelling, doi:10.1016/j.ocemod.2007.10.007. Song, Y. T. (2007) Detecting tsunami genesis and scales directly from coastal GPS stations, Geophys. Res. Lett., 34, L19602, doi:10.1029/2007GL031681.

  5. EFFECT OF SITE ON BACTERIAL POPULATIONS IN THE SAPWOOD OF COARSE WOODY DEBRIS.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Porter, Emma, G.,; Waldrop, Thomas, A.; McElreath, Susan, D.

    1998-01-01

    Porter, Emma G., T.A. Waldrop, Susan D. McElreath, and Frank H. Tainter. 1998. Effect of site on bacterial populations in the sapwood of coarse woody debris. Pp. 480-484. In: Proc. 9th Bienn. South. Silv. Res. Conf. T.A. Waldrop (ed). USDA Forest Service, Southern Research Station. Gen. Tech. Rep. SRS-20. Abstract: Coarse woody debris (CWD) is an important structural component of southeastern forest ecosystems, yet little is known about its dynamics in these systems. This project identified bacterial populations associated with CWD and their dynamics across landscape ecosystem classification (LEC) units. Bolts of red oak and loblolly pine were placed onmore » plots at each of three hydric, mesic, and xeric sites at the Savannah River Station. After the controls were processed, samples were taken at four intervals over a 16-week period. Samples were ground within an anaerobe chamber using nonselective media. Aerobic and facultative anaerobic bacteria were identified using the Biolog system and the anaerobes were identified using the API 20A system. Major genera isolated were: Bacillus, Buttiauxella, Cedecea, Enterobacter, Erwinia, Escherichia, Klebsiella, Pantoea, Pseudomonas, Serratia, and Xanthomonas. The mean total isolates were determined by LEC units and sample intervals. Differences occurred between the sample intervals with total isolates of 6.67, 13.33, 10.17, and 9.50 at 3, 6, 10, and 16 weeks, respectively. No significant differences in the numbers of bacteria isolated were found between LEC units.« less

  6. Chemical Technology Division: Progress report, January 1, 1987--June 30, 1988

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1989-02-01

    This progress report summarizes the research and development efforts conducted in the Chemical Technology Division (Chem Tech) during the period January 1, 1987, to June 30, 1988. The following major areas are covered: waste management and environmental programs, radiochemical and reactor engineering programs, basic science and technology, Nuclear Regulatory Commission programs, and administrative resources and facilities. The Administrative Summary, an appendix, presents a comprehensive listing of publications, oral presentations, awards and recognitions, and patents of Chem Tech staff members during this period. A staffing level and financial summary and lists of seminars and Chem Tech consultants for the period aremore » also included.« less

  7. Prime Contract Awards by Service Category and Federal Supply Classification, Fiscal Years 1981, 1982, 1983, 1984.

    DTIC Science & Technology

    1984-01-01

    SERVICE/VALVES 77 0 0 0 11349 INSPECTION SERVICE’MAINTENANCE SHOP EQ 0 855 0 131 11352 INSPECTIONf SERVICE’IMEASURING TOOLS 0 0 00 H354 INPECTION...INST-RADIO-TV 46 226 254 06 J307: MAINTr-REPAIR OF EQ/RECREATIONAL EQUIP ISO 434 302 347 J3076 MAINY-REPAI OF EQ/ CL EANING EQUIP 106 44 111 62 .1060...VALVES 0 0 40 0 LO4 TECH REP SERVICES /MAINTENANCE SHOP EO 2,294 300 1,212 ISO LO52 TECH REP SERVICES /MEASURING TOOLS NA 161 ,695 3.264 LO3 TECH REP

  8. Methodological Choices in Muscle Synergy Analysis Impact Differentiation of Physiological Characteristics Following Stroke

    PubMed Central

    Banks, Caitlin L.; Pai, Mihir M.; McGuirk, Theresa E.; Fregly, Benjamin J.; Patten, Carolynn

    2017-01-01

    Muscle synergy analysis (MSA) is a mathematical technique that reduces the dimensionality of electromyographic (EMG) data. Used increasingly in biomechanics research, MSA requires methodological choices at each stage of the analysis. Differences in methodological steps affect the overall outcome, making it difficult to compare results across studies. We applied MSA to EMG data collected from individuals post-stroke identified as either responders (RES) or non-responders (nRES) on the basis of a critical post-treatment increase in walking speed. Importantly, no clinical or functional indicators identified differences between the cohort of RES and nRES at baseline. For this exploratory study, we selected the five highest RES and five lowest nRES available from a larger sample. Our goal was to assess how the methodological choices made before, during, and after MSA affect the ability to differentiate two groups with intrinsic physiologic differences based on MSA results. We investigated 30 variations in MSA methodology to determine which choices allowed differentiation of RES from nRES at baseline. Trial-to-trial variability in time-independent synergy vectors (SVs) and time-varying neural commands (NCs) were measured as a function of: (1) number of synergies computed; (2) EMG normalization method before MSA; (3) whether SVs were held constant across trials or allowed to vary during MSA; and (4) synergy analysis output normalization method after MSA. MSA methodology had a strong effect on our ability to differentiate RES from nRES at baseline. Across all 10 individuals and MSA variations, two synergies were needed to reach an average of 90% variance accounted for (VAF). Based on effect sizes, differences in SV and NC variability between groups were greatest using two synergies with SVs that varied from trial-to-trial. Differences in SV variability were clearest using unit magnitude per trial EMG normalization, while NC variability was less sensitive to EMG normalization method. No outcomes were greatly impacted by output normalization method. MSA variability for some, but not all, methods successfully differentiated intrinsic physiological differences inaccessible to traditional clinical or biomechanical assessments. Our results were sensitive to methodological choices, highlighting the need for disclosure of all aspects of MSA methodology in future studies. PMID:28912707

  9. Methodological Choices in Muscle Synergy Analysis Impact Differentiation of Physiological Characteristics Following Stroke.

    PubMed

    Banks, Caitlin L; Pai, Mihir M; McGuirk, Theresa E; Fregly, Benjamin J; Patten, Carolynn

    2017-01-01

    Muscle synergy analysis (MSA) is a mathematical technique that reduces the dimensionality of electromyographic (EMG) data. Used increasingly in biomechanics research, MSA requires methodological choices at each stage of the analysis. Differences in methodological steps affect the overall outcome, making it difficult to compare results across studies. We applied MSA to EMG data collected from individuals post-stroke identified as either responders (RES) or non-responders (nRES) on the basis of a critical post-treatment increase in walking speed. Importantly, no clinical or functional indicators identified differences between the cohort of RES and nRES at baseline. For this exploratory study, we selected the five highest RES and five lowest nRES available from a larger sample. Our goal was to assess how the methodological choices made before, during, and after MSA affect the ability to differentiate two groups with intrinsic physiologic differences based on MSA results. We investigated 30 variations in MSA methodology to determine which choices allowed differentiation of RES from nRES at baseline. Trial-to-trial variability in time-independent synergy vectors (SVs) and time-varying neural commands (NCs) were measured as a function of: (1) number of synergies computed; (2) EMG normalization method before MSA; (3) whether SVs were held constant across trials or allowed to vary during MSA; and (4) synergy analysis output normalization method after MSA. MSA methodology had a strong effect on our ability to differentiate RES from nRES at baseline. Across all 10 individuals and MSA variations, two synergies were needed to reach an average of 90% variance accounted for (VAF). Based on effect sizes, differences in SV and NC variability between groups were greatest using two synergies with SVs that varied from trial-to-trial. Differences in SV variability were clearest using unit magnitude per trial EMG normalization, while NC variability was less sensitive to EMG normalization method. No outcomes were greatly impacted by output normalization method. MSA variability for some, but not all, methods successfully differentiated intrinsic physiological differences inaccessible to traditional clinical or biomechanical assessments. Our results were sensitive to methodological choices, highlighting the need for disclosure of all aspects of MSA methodology in future studies.

  10. Cancer Treatment Side Effects: A Meta-analysis of the Relationship Between Response Expectancies and Experience.

    PubMed

    Devlin, Elise J; Denson, Linley A; Whitford, Hayley S

    2017-08-01

    Although previous research has, overall, suggested a moderate relationship between response expectancies (REs) and cancer treatment-related side effects, empirical results have been mixed. We aimed to further explore these relationships, hypothesizing that REs would predict subsequent toxicities with the inclusion of more recent studies, across a broader range of side effects, while incorporating the impact of potential moderators including patients' experience with treatment and measurement methods. We further investigated the impact of REs across individual toxicities. A systematic search and analysis were conducted across four databases (PsychInfo, PubMed, CINAHL, and Embase) and reference lists, from 1985 to February 2016. This provided 27 eligible studies with 4474 participants, through which the main analysis, moderator analyses, and individual side-effect analyses were explored. REs were moderately related to side effects overall (r = 0.26), and effect sizes were significantly influenced by sample diagnostic homogeneity, whereas differences between type and timing of measurement showed trends. Of the 16 toxicities examined, 15 demonstrated significant relationships between REs and side-effect experience, with hair loss (r = 0.48) the strongest. No clear difference emerged between objective and subjective side effects; however, significant differences across individual toxicities were revealed. Findings support a relationship between REs and a wide range of subsequent side effects, yet differences between individual RE-toxicity associations emerged. These findings provide direction for the measurement of side effects and REs and support REs as potential targets for intervention during the informed consent process. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

  11. Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF).

    PubMed

    Vancauwenberghe, Eric; Noyer, Lucile; Derouiche, Sandra; Lemonnier, Loïc; Gosset, Pierre; Sadofsky, Laura R; Mariot, Pascal; Warnier, Marine; Bokhobza, Alexandre; Slomianny, Christian; Mauroy, Brigitte; Bonnal, Jean-Louis; Dewailly, Etienne; Delcourt, Philippe; Allart, Laurent; Desruelles, Emilie; Prevarskaya, Natalia; Roudbaraki, Morad

    2017-08-01

    Previous studies showed the effects of resveratrol (RES) on several cancer cells, including prostate cancer (PCa) cell apoptosis without taking into consideration the impact of the tumor microenvironment (TME). The TME is composed of cancer cells, endothelial cells, blood cells, and cancer-associated fibroblasts (CAF), the main source of growth factors. The latter cells might modify in the TME the impact of RES on tumor cells via secreted factors. Recent data clearly show the impact of CAF on cancer cells apoptosis resistance via secreted factors. However, the effects of RES on PCa CAF have not been studied so far. We have investigated here for the first time the effects of RES on the physiology of PCa CAF in the context of TME. Using a prostate cancer CAF cell line and primary cultures of CAF from prostate cancers, we show that RES activates the N-terminal mutated Transient Receptor Potential Ankyrin 1 (TRPA1) channel leading to an increase in intracellular calcium concentration and the expression and secretion of growth factors (HGF and VEGF) without inducing apoptosis in these cells. Interestingly, in the present work, we also show that when the prostate cancer cells were co-cultured with CAF, the RES-induced cancer cell apoptosis was reduced by 40%, an apoptosis reduction canceled in the presence of the TRPA1 channel inhibitors. The present work highlights CAF TRPA1 ion channels as a target for RES and the importance of the channel in the epithelial-stromal crosstalk in the TME leading to resistance to the RES-induced apoptosis. © 2017 Wiley Periodicals, Inc.

  12. Role of resilience and social support in alleviating depression in patients receiving maintenance hemodialysis.

    PubMed

    Liu, Yueh-Min; Chang, Hong-Jer; Wang, Ru-Hwa; Yang, Li-King; Lu, Kuo-Cheng; Hou, Yi-Chou

    2018-01-01

    Patients who undergo hemodialysis encounter challenges including role changes, physical degeneration, and difficulty in performing activities of daily living (ADLs) and self-care. These challenges deteriorate their physiological and psychosocial conditions, resulting in depression. High resilience (RES) and social support can alleviate stress and depression. This study evaluated the importance of RES and social support in managing depression in elderly patients undergoing maintenance hemodialysis (HD). In this descriptive, correlational study, 194 older patients undergoing HD were enrolled from the HD centers of three hospitals in northern Taiwan. The Barthel ADL Index, RES scale, Inventory of Socially Supportive Behavior, and Beck Depression Inventory-II were used. Hierarchical regression analysis was applied to evaluate the interaction of RES and social support with illness severity, demographics, and ADLs. Of the total participants, 45.9% experienced depressive symptoms. Demographic analysis showed that men and those with high educational level and income and financial independence had less depression ( p <0.01). Patients with a higher Barthel Index (n=103), RES scale (n=33), and social support (n=113) showed less depressive symptoms ( p <0.01). We found a significant negative correlation between depressive symptoms and social support ( r =-0.506, p <0.01) and RES ( r =-0.743, p <0.01). Hierarchical regression analysis showed that RES could buffer the effects of symptom severity on depression ( b =-0.436, p <0.01), but social support did not exert a buffering effect. The severity of illness symptoms and ADLs were the major determinants of depressive symptoms. High RES could alleviate depressive symptoms in the older patients undergoing HD.

  13. DoD Science and Engineering Apprenticeship Program for High-School Students

    DTIC Science & Technology

    1995-06-01

    Mu Alpha Theta for Computers, Calculus, Integral Calculus, and Precalculus ; 1994 Georgia Tech Distinguished Math Scholar; Captain of First Place...Computers. Calr.uIns. TntPg^i Painii»«. and Precalculus ; 1994 Georgia Tech Distinguished Math Scholar;.Captain of.First.Place Brain Bowl

  14. NASA Tech Briefs, July 1998. Volume 22, No. 7

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Topics include: special coverage on graphics and simulation, electronic components and circuits, electronic systems, materials, a second special coverage on mechanical technology, machinery/automation, and a special section of electronics Tech Briefs. There is also a section devoted to the technology of the International Space Station.

  15. KSC Tech Transfer News, Volume 5, No. 2

    NASA Technical Reports Server (NTRS)

    Nichols, James D.

    2013-01-01

    Kennedy Tech Transfer News is the semiannual magazine of the Innovative Partnerships Program Office at NASA Kennedy Space Center in Cape Canaveral, Florida. This magazine seeks to inform and educate cMI servant and Contractor personnel at Kennedy about actively participating in achieving NASA's technology transfer goals

  16. An Automated Slide Classification System at Georgia Tech

    ERIC Educational Resources Information Center

    LoPresti, Maryellen

    1973-01-01

    The Georgia Tech Architecture Library slide collection is being revolutionized by adapting the Santa Cruz Slide Classification System. The slide catalog record is being transferred inexpensively to tapes and updated by the computer. Computer programs print out indexes in any of fifteen different sort fields. (Author)

  17. Not Just for CTE Teachers

    ERIC Educational Resources Information Center

    Reese, Susan

    2005-01-01

    Connecting education and careers through professional development experiences can benefit academic teachers as well as career tech teachers. At the Upper Rio Grande College Tech-Prep Youth Consortium in El Paso, Texas, there is a professional development program that helps academic teachers see the connection between learning and earning. A…

  18. 2 CFR Appendix C to Part 230 - Non-Profit Organizations Not Subject to This Part

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., Michigan 11. Georgia Institute of Technology/Georgia Tech Applied Research Corporation/Georgia Tech Research Institute, Atlanta, Georgia 12. Hanford Environmental Health Foundation, Richland, Washington 13... Institutes of Research (AIR), Washington DC 4. Argonne National Laboratory, Chicago, Illinois 5. Atomic...

  19. 75 FR 45159 - Delphi Steering Currently Known as Nexteer Automotive Including On-Site Leased Workers From Acro...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ..., Inc., Continental, Inc., Dynamic Corp., G-Tech Professional Staffing, Inc., Globaledgetechnologies... Corporation, Aerotek, Inc., Continental, Inc., Dynamic Corp., G-Tech Professional Staffing, Inc., Globaledge... steering systems and components such as steering columns, gears, pumps and electronic power steering...

  20. Tech-Know: Integrating Engaging Activities through Standards-Based Learning

    ERIC Educational Resources Information Center

    Ernst, Jeremy V.; Taylor, Jerianne S.; Peterson, Richard E.

    2005-01-01

    In August 2001, North Carolina State University received a four-year grant from the National Science Foundation to develop standards-based instructional materials for 20 Technology Student Association (TSA) activities. The TECH-know Project represents a significant collaboration between selected state departments, universities, businesses, and…

  1. On-Demand Lectures Create an Effective Distributed Education Experience

    ERIC Educational Resources Information Center

    Lindsey, Stanley D.

    2003-01-01

    In this article, the author shares his experience teaching senior-level structural engineering courses at the Georgia Institute of Technology's Georgia Tech Regional Engineering Program. The program is a unique partnership of four universities--Georgia Tech, Savannah State University, Armstrong Atlantic State University, and Georgia Southern…

  2. NASA Tech Briefs, March 1999. Volume 23, No. 3

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Topics include: special coverage sections on CAD/CAE/PDM, industrial controls and sections on electronic components systems, materials, software, mechanics, machinery/automation, manufacturing/fabrication, physical sciences, book and reports, and a special section of Photonics Tech Briefs and a seconds special section of Rapid Product Development.

  3. Resistor Susceptibility Survey

    DTIC Science & Technology

    1976-11-01

    SATIN IV ATTN: DCKE, L. Staples ATTN. YWES ATTN XRE-Surv. ATTN- MCAE, Lt Col Sparks ATTN: XRP , Maj Gingrich Sandia Lab. ATTN 3141 ATTN E...Diamond Lab. ATTN: Lib. HQ USAF ATTN: XOOWD AFSC Tech. Lib. ATTN: DLCAW ATTN: XRP ! Sperry Rand Fit. Sys. Div. ATTN: Tech. Lib. ATTN: D

  4. Special Report: Vocational Training in the High-Tech Age.

    ERIC Educational Resources Information Center

    Mansnerus, Laura; And Others

    1994-01-01

    "New Pressures on Vocational Education" (Mansnerus) describes new forms (tech prep, career academies, apprenticeship, school enterprises); "Biotechnology Goes to High School" (Quinn) describes Berkeley High's Biotech Academy created by industry; and "Votech That Works" (Holusha) stresses the importance of specialized training for non-college-bound…

  5. SITE DEMONSTRATION BULLETIN - ENHANCED IN-SITU BIOREMEDIATION PROCESS, EARTH TECH, INC.

    EPA Science Inventory

    The USEPA conducted an evaluation of the Enhanced In-situ Bioremediation process, a biostimulation technology developed by the USDOE at the Westinghouse Savannah River Plant site in Aiken, SC. DOE has licensed the process to Earth Tech, Inc. The evaluation described in this bulle...

  6. Peer review statement

    NASA Astrophysics Data System (ADS)

    2012-11-01

    All papers published in this volume of Journal of Physics: Conference Series have been peer reviewed through processes administered by the editors of the 26th IAHR Symposium on Hydraulic Machinery and Systems proceedings. Reviews were conducted by expert referees from the International Technical Committee to the professional and scientific standards expected of a proceedings journal published by IOP Publishing. The members of the Scientific Committee who selected and reviewed the papers included in the Proceedings of the 26th IAHR Symposium on Hydraulic Machinery and Systems are: Yulin WU Tsinghua University China François AVELLAN EPFL-LMH Switzerland (principal) Xingqi LUO Xi'an University of Sci & Tech China Martin BÖHLE Kaiserslautern University Germany Gerard BOIS Arts et Métiers ParisTech France Luca D'AGOSTINO University of Pisa Italy Eduard EGUSQUIZA Polytechnical University Catalonia Spain Richard FISHER Voith Hydro Inc USA Regiane FORTES-PATELLA Institute Polytechnique de Grenoble France Aleksandar GAJIC University of Belgrade Serbia Wei YANG China Agriculture University China YinLu YOUNG University of Michigan USA Adrian LUNGU Dunarea de Jos University of Galati Romania Arpad FAY University of Miskolcz Hungary José GONZÁLEZ Universidad de Oviedo Spain Baoshan ZHU Tsinghua University China Hongxun CHEN Shanghai University China Chisachi KATO University of Tokyo Japan Zhenyue MA Dalian University of Sci & Tech China Honggang FAN Tsinghua University China François GUIBAULT Ecole Polytechnique de Montreal Canada Pengcheng GUO Xian University of Technology China Leqing WANG Zhejiang University China Toshiaki IKOHAGI Tohoku University Japan Jiandong YANG Wuhan University China Jianzhong ZHOU Huazhong University of Sci & Tech China Jinwei LI NULL China Rennian LI Lanzhou University of Sci & Tech China Houlin LIU NULL China Juan LIU Tsinghua University China Shuhong LIU Tsinghua University China Xianwu LUO Tsinghua University China Michihiro NISHI Tsinghua University China Peter PELZ Darmstadt University Germany František POCHYLY Brno University Czech Republic Rudolf SCHILLING Technische Universität München Germany Minguan YANG Jiangsu University China Smaine KOUIDRI Université Pierre et Marie Curie (Paris 6) France Kazuhiro TANAKA Kyushu Institute of Technology Japan Xuelin TANG Tsinghua University China Yoshinobu TSUJIMOTO Osaka University Japan Fujun WANG China Agriculture University China Guoyu WANG Beijing University of Sci & Tech China Wenwu SONG NULL China Zhengwei WANG Tsinghua University China Hongyuan XU Tsinghua University China Lefu XIAO NULL China Fan YANG Tsinghua University China Yuan ZHENG Hehai University China Zhigang ZUO Tsinghua University China Hongwu ZHU China Petroleum University China Lixiang ZHANG Yunnan University of Sci & Tech China Shengchang ZHANG Zhejiang University of Tech China

  7. TechCare: mobile assessment and therapy for psychosis - an intervention for clients in the Early Intervention Service: A feasibility study protocol.

    PubMed

    Husain, Nusrat; Gire, Nadeem; Kelly, James; Duxbury, Joy; McKeown, Mick; Riley, Miv; Taylor, Christopher Dj; Taylor, Peter J; Emsley, Richard; Farooq, Saeed; Caton, Neil; Naeem, Farooq; Kingdon, David; Chaudhry, Imran

    2016-01-01

    Technological advances in healthcare have shown promise when delivering interventions for mental health problems such as psychosis. The aim of this project is to develop a mobile phone intervention for people with psychosis and to conduct a feasibility study of the TechCare App. The TechCare App will assess participant's symptoms and respond with a personalised guided self-help-based psychological intervention with the aim of exploring feasibility and acceptability. The project will recruit 16 service users and 8-10 health professionals from the Lancashire Care NHS Foundation Trust Early Intervention Service. In strand 1 of the study, we will invite people to discuss their experience of psychosis and give their opinions on the existing evidence-based treatment (cognitive behavioural therapy) and how the mobile app can be developed. In strand 2, we will complete a test run with a small number of participants (n = 4) to refine the mobile intervention (TechCare). Finally, in strand 3 of the study, the TechCare App will be examined in a feasibility study with 12 participants. It has been suggested that there is a need for a rapid increase in the efforts to develop the evidence base for the clinical effectiveness of digital technologies, considering mHealth research can potentially be helpful in addressing the demand on mental health services globally.

  8. 2014 International Conference on Science & Engineering in Mathematics, Chemistry and Physics (ScieTech 2014)

    NASA Astrophysics Data System (ADS)

    2014-04-01

    2014 International Conference on Science & Engineering in Mathematics, Chemistry and Physics (ScieTech 2014), was held at the Media Hotel, Jakarta, Indonesia, on 13-14 January 2014. The ScieTech 2014 conference is aimed to bring together researchers, engineers and scientists in the domain of interest from around the world. ScieTech 2014 is placed on promoting interaction between the theoretical, experimental, and applied communities, so that a high level exchange is achieved in new and emerging areas within Mathematics, Chemistry and Physics. We would like to express our sincere gratitude to all in the Technical Program Committee who have reviewed the papers and developed a very interesting Conference Program as well as the invited and plenary speakers. This year, we received 187 papers and after rigorous review, 50 papers were accepted. The participants come from 16 countries. There are 5 (Five) Paralell Sessions and Four Keynote Speakers. It is an honour to present this volume of Journal of Physics: Conference Series (JPCS) and we deeply thank the authors for their enthusiastic and high-grade contributions. Finally, we would like to thank the conference chairmen, the members of the steering committee, the organizing committee, the organizing secretariat and the financial support from the conference sponsors that allowed the success of ScieTech 2014. The Editors of the Scietech 2014 Proceedings: Dr. Ford Lumban Gaol Dr. Benfano Soewito Dr. P.N. Gajjar

  9. NREL: International Activities - Pakistan Resource Maps

    Science.gov Websites

    . The high-resolution (1-km) annual wind power maps were developed using a numerical modeling approach along with NREL's empirical validation methodology. The high-resolution (10-km) annual and seasonal KB) | High-Res (ZIP 281 KB) 40-km Resolution Annual Maps (Direct) Low-Res (JPG 156 KB) | High-Res

  10. ResStock - Targeting Energy and Cost Savings for U.S. Homes | NREL

    Science.gov Websites

    ResStock - Targeting Energy and Cost Savings for U.S. Homes Science and Technology Highlights Highlights in Research & Development ResStock - Targeting Energy and Cost Savings for U.S. Homes Key discovered $49 billion in potential annual utility bill savings through cost-effective energy efficiency

  11. University of Utrecht 1636-1676: "Res Ecclesia, Res Publica and … Res Pecunia"

    ERIC Educational Resources Information Center

    van Rinsum, Henk; Koops, Willem

    2016-01-01

    The early history of Utrecht University (founded 1636) reflects an emerging public sphere (Habermas's "bürgerliche öffentlichkeit") of a major town in the Netherlands. This public sphere was a contested field among the different groups establishing and administering the university: university professors, town magistrates and…

  12. Neuroprotective effect of resveratrol against brain ischemia reperfusion injury in rats entails reduction of DJ-1 protein expression and activation of PI3K/Akt/GSK3b survival pathway.

    PubMed

    Abdel-Aleem, Ghada A; Khaleel, Eman F; Mostafa, Dalia G; Elberier, Lydia K

    2016-10-01

    In the current study, we aimed to investigate the mechanistic role of DJ-1/PI3K/Akt survival pathway in ischemia/reperfusion (I/R) induced cerebral damage and to investigate if the resveratrol (RES) mediates its ischemic neuroptotection through this pathway. RES administration to Sham rats boosted glutathione level and superoxide dismutase activity and downregulated inducible nitric oxide synthase expression without affecting redox levels of DJ-1 forms or components of PI3K/Akt pathway including PTEN, p-Akt or p/p-GSK3b. However, RES pre-administration to I/R rats reduced infarction area, oxidative stress, inflammation and apoptosis. Concomitantly, RES ameliorated the decreased levels of oxidized forms of DJ-1 and enhancing its reduction, increased the nuclear protein expression of Nfr-2 and led to activation of PI3K/Akt survival pathway. In conclusion, overoxidation of DJ-1 is a major factor that contributes to post-I/R cerebral damage and its reduction by RES could explain the neuroprotection offered by RES.

  13. Influence of signal processing strategy in auditory abilities.

    PubMed

    Melo, Tatiana Mendes de; Bevilacqua, Maria Cecília; Costa, Orozimbo Alves; Moret, Adriane Lima Mortari

    2013-01-01

    The signal processing strategy is a parameter that may influence the auditory performance of cochlear implant and is important to optimize this parameter to provide better speech perception, especially in difficult listening situations. To evaluate the individual's auditory performance using two different signal processing strategy. Prospective study with 11 prelingually deafened children with open-set speech recognition. A within-subjects design was used to compare performance with standard HiRes and HiRes 120 in three different moments. During test sessions, subject's performance was evaluated by warble-tone sound-field thresholds, speech perception evaluation, in quiet and in noise. In the silence, children S1, S4, S5, S7 showed better performance with the HiRes 120 strategy and children S2, S9, S11 showed better performance with the HiRes strategy. In the noise was also observed that some children performed better using the HiRes 120 strategy and other with HiRes. Not all children presented the same pattern of response to the different strategies used in this study, which reinforces the need to look at optimizing cochlear implant clinical programming.

  14. Nanoparticle-macrophage interactions: A balance between clearance and cell-specific targeting

    PubMed Central

    Rattan, Rahul; Bhattacharjee, Somnath; Zong, Hong; Swain, Corban; Siddiqui, Muneeb A.; Visovatti, Scott H.; Kanthi, Yogendra; Desai, Sajani; Pinsky, David J.; Goonewardena, Sascha N.

    2017-01-01

    The surface properties of nanoparticles (NPs) are a major factor that influences how these nanomaterials interact with biological systems. Interactions between NPs and macrophages of the reticuloendothelial system (RES) can reduce the efficacy of NP diagnostics and therapeutics. Traditionally, to limit NP clearance by the RES system, the NP surface is neutralized with molecules like poly(ethylene glycol) (PEG) which are known to resist protein adsorption and RES clearance. Unfortunately, PEG modification is not without drawbacks including difficulties with the synthesis and associations with immune reactions. To overcome some of these obstacles, we neutralized the NP surface by acetylation and compared this modification to PEGylation for RES clearance and tumor-specific targeting. We found that acetylation was comparable to PEGylation in reducing RES clearance. Additionally, we found that dendrimer acetylation did not impact folic acid (FA)-mediated targeting of tumor cells whereas PEG surface modification reduced the targeting ability of the NP. These results clarify the impact of different NP surface modifications on RES clearance and cell-specific targeting and provide insights into the design of more effective NPs. PMID:28705434

  15. US defensive operations against Libya and the nuclear accident at Chernobyl. Markup before the Committee on Foreign Affairs, House of Representatives, Ninety-Ninth Congress, Second Session on H. Res. 424 and H. Res 440, May 1, 1986

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1986-01-01

    The House Foreign Affairs Committee met to mark up two resolutions: H. Res. 424 and H. Res. 440. H. Res. 424 thanks the United Kingdom for its assistance in the April 14, 1986 operation against Libya. Despite objections to the raid and to including the British, as well as questions about the quality of the US response and about the President's compliance with the Constitution and the War Powers Resolution, the resolution passed. H. Res. 440 expresses sympathy to the victims of the Chernobyl accident and asks the Soviet Union to relax restrictions on communications and the transfer of whatevermore » technology and assistance will be helpful. It also criticizes the Soviet handling of information about the accident. An amendment strengthened the wording of the criticism, and the resolution passed. The report includes the committee discussion and the tests of the two resolutions.« less

  16. Effects of ranavirus infection of red-eared sliders (Trachemys scripta elegans) on plasma proteins.

    PubMed

    Moore, A Russell; Allender, Matthew C; MacNeill, Amy L

    2014-06-01

    Ranavirus is an emerging disease that infects fish, amphibians, and reptiles. Ranavirus induces an inflammatory response leading to death in many susceptible species. Red-eared sliders (RES; Trachemys scripta elegans) are vulnerable to ranavirus infection and are economically significant chelonians kept in the pet trade and utilized in research. Early identification of RES with inflammatory diseases would allow for isolation of affected individuals and subsequent disease investigation, including molecular testing for ranavirus. Validation of an inexpensive, clinically relevant, and reproducible diagnostic test that detects inflammation in turtles is needed. Although commonly used, plasma protein electrophoresis to detect an inflammatory acute-phase protein response has not been evaluated in a controlled environment in turtles with experimentally induced inflammatory disease. The objective of this study was to measure plasma protein fractions by electrophoresis to determine if an acute-phase protein response occurs in RES during infection with a frog virus 3-like ranavirus (FV3-like virus) isolated from a chelonian. A Bradford assay and agarose gel electrophoresis (AGE) were performed using plasma collected during a study of the effect of temperature on the pathogenesis of ranavirus in RES. In RES at the time of viremia, total albumin (ALB(mg/ml)) and albumin to globulin ratio were significantly lower and beta-globulin percentage was significantly higher in RES exposed to ranavirus (n = 4) as compared to matched, uninfected RES (n = 8). In the last sample collected prior to death, total protein (TP(mg/ml)), ALB(mg/ml), alpha-globulin percentage, and total alpha-globulin (alpha(mg/ml)) were significantly lower in RES exposed to ranavirus (n = 4) than control individuals (n = 8). In summary, FV3-like virus induces a decrease in plasma albumin concentration at the onset ofviremia and decreases in TP(mg/ml, ALB(mg/ml), and alpha(mg/ml) concentrations prior to death in RES as measured by AGE.

  17. Hepatic transcriptome analysis of juvenile GIFT tilapia (Oreochromis niloticus), fed diets supplemented with different concentrations of resveratrol.

    PubMed

    Zheng, Yao; Wu, Wei; Hu, Gengdong; Zhao, Zhixiang; Meng, Shunlong; Fan, Limin; Song, Chao; Qiu, Liping; Chen, Jiazhang

    2018-01-01

    The GIFT (Genetically Improved Farmed Tilapia) tilapia, Oreochromis niloticus, is cultured widely for the production of freshwater fish in China. Streptococcosis, which is related to pathogenic infections, occurs frequently in juvenile and adult female GIFT individuals. Resveratrol (RES) has been used in feed to control these infections in freshwater tilapia. To address the effects of RES on tilapia, we used high-throughput RNA sequencing technology (RNA-Seq, HiSeq. 2500) to explore the global transcriptomic response and specific involvement of hepatic mRNA of juvenile O. niloticus fed with diets containing different concentrations of (0, 0.025, 0.05, and 0.1g/kg) RES. A total of > 24,513,018 clean reads were generated and then assembled into 23,244 unigenes. The unigenes were annotated by comparing them against non-redundant protein sequence (Nr), non-redundant nucleotide (Nt), Swiss-Prot, Pfam, Gene Ontology database (GO), Clusters of Orthologous Groups (COG) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, and 12,578 unigenes were annotated to the GO database. A total of 1444 (0.025g/kg RES), 1526 (0.05g/kg RES), and 3135 (0.1g/kg RES) genes were detected as significant differentially expressed genes (DEGs), when compared with the controls. A total of 6 (0.025 vs 0.05g/kg RES), 19 (0.025 vs 0.1g/kg RES), and 124 (0.05 vs 0.1g/kg RES) genes were detected as significant DEGs. Six genes, including dnah7x1, sox4, fam46a, hsp90a, ddit4, and nmrk2, were associated with an immune response. These findings provide information on the innate immunity of GIFT and might contribute to the development of strategies for the effective management of diseases and long-term sustainability of O. niloticus culture. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Alleviation of Acute Lung Injury in Rats with Sepsis by Resveratrol via the Phosphatidylinositol 3-Kinase/Nuclear Factor-Erythroid 2 Related Factor 2/Heme Oxygenase-1 (PI3K/Nrf2/HO-1) Pathway.

    PubMed

    Wang, Yu; Wang, Xiaofeng; Zhang, Lichun; Zhang, Rong

    2018-05-30

    BACKGROUND Resveratrol (Res) is a type of polyphenol found in many plants, which can protect important organs from the damage induced by sepsis. However, the exact mechanism of its protective effect has not been established. This study investigated the effect of Res on the PI3K/Nrf2/HO-1 signaling pathway in rats with sepsis-induced acute lung injury (ALI). MATERIAL AND METHODS Male Wistar rats were treated with 30 mg/kg Res by intraperitoneal administration for 1 hour immediately after cecal ligation and puncture. Levels of MIP-2, IL-18, and IL-10 in bronchoalveolar lavage fluid (BALF) were determined. Lung tissues were collected to measure the wet-to-dry (W/D) ratios, oxidative stress index, and lung injury scores. Expression levels of Akt, p-Akt, HO-1, Nrf-2, and active caspase-3 proteins were determined by western blotting; expression of HO-1 mRNA was determined by RT-PCR. RESULTS Treatment with Res significantly decreased the levels of MIP-2 and IL-18 and increased IL-10 in the BALF of rats with sepsis-induced ALI. In addition, Res also effectively reduced the W/D lung weight ratio, lung injury score, and the levels of MDA (malondialdehyde) and 8-OHdG. Conversely, Res increased SOD (superoxide dismutase) activity in the lung tissue. Moreover, Res significantly induced higher HO-1 mRNA expression, upregulated HO-1 and Nrf-2 protein expression, and the phosphorylation of Akt in the lung tissue. In contrast, the levels of activated caspase-3 protein were decreased in Res-treated rats (P<0.05). CONCLUSIONS Res could inhibit inflammation, oxidative stress, and cell apoptosis to alleviate ALI in septic rats through the inhibition of the PI3K/Nrf2/HO-1 signaling pathway.

  19. Electromechanical Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 25 units to consider for use in a tech prep competency profile for the occupation of electromechanical technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and…

  20. Tool & Die Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 23 units to consider for use in a tech prep competency profile for the occupation of tool and die technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and…

  1. Effect of Nanotechnology Instructions on Senior High School Students

    ERIC Educational Resources Information Center

    Lu, Chow-Chin; Sung, Chia-Chi

    2011-01-01

    In this research, we cooperate with senior high school teachers to understand current nanotechnology model of senior high school nanotechnology curriculum in Taiwan. Then design senior high school nanotechnology (nano-tech) curriculum to teach 503 senior high school students. After teaching the nano-tech curriculum we use the "Nanotechnology…

  2. CADD Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 22 units to consider for use in a tech prep competency profile for the occupation of CADD (computer-assisted drafting and design) technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within…

  3. Electronics Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 27 units to consider for use in a tech prep competency profile for the occupation of electronics technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and would…

  4. Re-conceptualsing Learning Spaces: Developing Capabilities in a High-Tech Small Firm.

    ERIC Educational Resources Information Center

    Macpherson, Allan; Jones, Ossie; Zhang, Michael; Wilson, Alison

    2003-01-01

    A case study of a small high-tech business explains how they created a virtual cluster of innovation through supply networks, enhancing their own learning and facilitating integration of knowledge. This process overcomes limitations to management learning for small companies in isolated regions. (Contains 66 references.) (SK)

  5. Virginia Tech State Task Force Reports Summary

    ERIC Educational Resources Information Center

    McBride, James T.

    2010-01-01

    An analysis of eleven state task force reports prompted by the tragic nature of the Virginia Tech shooting in 2007 revealed that all shared a primary theme: no "single best way" to protect American college and university campuses yet exists. These documents, individually and collectively, make it clear that contemporary complex learning…

  6. NASA Tech Briefs, October 1995. Volume 19, No. 10

    NASA Technical Reports Server (NTRS)

    1995-01-01

    A special focus in this issue is Data acquisition and analysis. Topics covered include : Electronic Components and Circuits; Electronic Systems; Physical Sciences; Materials; Life Sciences; Mechanics; Machinery; Fabrication Technology; and Mathematics and Information Sciences. Also included in this issue are Laser Tech Briefs and Industry Focus: Motion Control/ Positioning Equipment

  7. Asia's New High-Tech Competitors: An SRS Special Report.

    ERIC Educational Resources Information Center

    Rausch, Lawrence M.

    This report profiles nine economies linked by Asian identity, yet marked by great economic and technological disparity, in order to project which economies will be full-fledged participants and competitors in tomorrow's high-tech product markets. Based on the various indicators of technological activity and competitiveness presented in this…

  8. Electronics Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile covers the occupation of electronics technician. Section 1 provides the occupation definition. Section 2 lists development committee members. Section 3 provides the leveling codes--abbreviations for grade level, (by the end of grade 12, by the end of associate degree), academic codes (communications, math, or…

  9. Plastics Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 16 units to consider for use in a tech prep competency profile for the occupation of plastics technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and would…

  10. Ending the Tech Refresh Nightmare

    ERIC Educational Resources Information Center

    Demski, Jennifer

    2010-01-01

    As higher education budgets tighten in the ongoing recession, colleges and universities have found themselves questioning, lengthening, and even eliminating tech refresh cycles. Yet how deep an institution cuts into its refresh program can compromise its ability to provide an up-to-date and competitive computing environment for students and a…

  11. Quality Control Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 18 units to consider for use in a tech prep competency profile for the occupation of quality control technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and…

  12. Music for Music's Sake and Tech for Tech's Sake

    ERIC Educational Resources Information Center

    Dunbar, Laura

    2016-01-01

    Technology is constantly changing, and it can be challenging to move beyond the "bells and whistles" of a new app or piece of software to confirm worthiness for classroom use. This article explores the balance point between technology use and more traditional modalities in the music classroom.

  13. Tech Prep Associate Degree: A Win/Win Experience.

    ERIC Educational Resources Information Center

    Hull, Dan, Comp.; Parnell, Dale, Comp.

    Designed to serve as a "how to" guide for policymakers, and state, federal, and institutional leaders, as well as public school and higher education practitioners interested in developing a Tech Prep/Associate Degree (TPAD) consortium, this book provides a detailed synthesis of successful TPAD consortia and programs. The first five…

  14. Low-Tech High-Tech.

    ERIC Educational Resources Information Center

    Hart, Tom

    1997-01-01

    Outlines how Compact Disc-interactive (CD-i)--software that looks like a CD-ROM but operates independently using a television set--can be used in elementary, secondary, and vocational education. Discusses the cost effectiveness of CD-i and compares costs and operational issues with CD-ROM. Describes special features of one CD-i program,…

  15. High Touch in a High-Tech World

    ERIC Educational Resources Information Center

    Gibson, Cindy L.

    2009-01-01

    In a world of high tech and low touch, it is easy for public relations programs to stray from tried-and-true interpersonal strategies long associated with solid communication planning. New technologies allow communications professionals to quickly send e-mails and telephone calls to selected groups. Social media sites provide users immediate…

  16. Electrical Maintenance Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 30 units to consider for use in a tech prep competency profile for the occupation of electrical maintenance technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific…

  17. Determining Studies Conducted upon Individuals with Autism Spectrum Disorder Using High-Tech Devices

    ERIC Educational Resources Information Center

    Eliçin, Özge; Kaya, Ali

    2017-01-01

    This study explores 67 experimental research articles written about children with Autism Spectrum Disorder using high-tech devices. The studies in this research were accessed through EBSCO, Academic Search Complete, ERIC, and Uludag University online search engines using keywords such as "autism and technology", "autism and…

  18. The Boeing Company's Manufacturing Technology Student Internship. Evaluation Report.

    ERIC Educational Resources Information Center

    Owens, Thomas R.

    The Boeing Company contracted with the Northwest Regional Educational Laboratory to evaluate its student internship program, part of a "school-to-work" effort modeled after the nationally recognized Tech Prep initiative. The company's involvement in the Tech Prep Program has been implemented in three phases: (1) the initial phase helped…

  19. Standard/Handbook for Multipactor Breakdown Prevention in Spacecraft Components

    DTIC Science & Technology

    2014-05-28

    Axley, Transient-mode Multipactor Discharge, Phys. Plasmas, 2009, 16, n. 8, pp. 083502-1 – 083502-7. 11. D. Woode and J. Petit. ESTEC Working Paper 1556...Bearings Scot Lichty scot.r.lichty@lmco.com Lockheed Martin Sultan Ali Lilani sultan.lilani@integra- tech.com Integra - Tech Josh Lindley

  20. Chicago Manufacturing Tech Prep. Fiscal Year 1991 Final Report.

    ERIC Educational Resources Information Center

    Chicago City Colleges, IL.

    During its first year of development in 1991, the Chicago Manufacturing Technical Preparation (Tech Prep) Program established a plan for implementing an industry-driven, articulated 4-year manufacturing technology course of study that integrates applied academic courses with technical courses and meets industry hiring standards. The project…

  1. 78 FR 57921 - Patch International, Inc., QuadTech International, Inc., Strategic Resources, Ltd., and Virtual...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... SECURITIES AND EXCHANGE COMMISSION [File No. 500-1] Patch International, Inc., QuadTech International, Inc., Strategic Resources, Ltd., and Virtual Medical Centre, Inc.; Order of Suspension of Trading... lack of current and accurate information concerning the securities of Virtual Medical Centre, Inc...

  2. Perceptions of Diversity Training Needs in High Tech Business.

    ERIC Educational Resources Information Center

    Lieberman, Devorah A.; Gurtov, Ellene

    A study questioned 12 human resource personnel, corporation managers, and diversity trainers about their perceptions of diversity training needs in Pacific Northwest high tech organizations. The overarching research questions for the study were as follows: (1) What are the most frequently reported diversity training needs among human resource…

  3. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT THE PROTECTOSEAL COMPANY PIN-TECH BUBBLE TIGHT < 500 PPM RELIEF VENT

    EPA Science Inventory

    The Environmental Technology Verification report discusses the technology and performance of a pressure relief valve for protection of storage tanks that operate at pressures of 15 psig or less. Four Pin-Tech Bubble Tight <500 ppm Relief Vent valves manufactured by the Protectose...

  4. Publications - GMC 311 | Alaska Division of Geological & Geophysical

    Science.gov Websites

    and Facilities Staff Seismic and Well Data Data Reports Contact Us Frequently Asked Questions Ask a DGGS GMC 311 Publication Details Title: Seal evaluation of NPRA well samples Authors: PetroTech information. Bibliographic Reference PetroTech Associates, 2004, Seal evaluation of NPRA well samples: Alaska

  5. Manufacturing (Industrial) Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 35 units to consider for use in a tech prep competency profile for the occupation of manufacturing (industrial) technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific…

  6. Mechanical Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 33 units to consider for use in a tech prep competency profile for the occupation of mechanical technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and would…

  7. Tech Prep Model for Marketing Education.

    ERIC Educational Resources Information Center

    Ruhland, Sheila K.; King, Binky M.

    A project was conducted to develop two tech prep models for marketing education (ME) in Missouri to provide a sequence of courses for skill-enhanced and time-shortened programs. First, labor market trends, employment growth projections, and business and industry labor needs in Missouri were researched and analyzed. The analysis results were used…

  8. Defense.gov Special Report: Travels With Carter

    Science.gov Websites

    . Story Carter Visits Silicon Valley Companies to Enhance DoD Technology Innovation Defense Secretary Ash innovation found in that part of the nation. Story Carter Seeks Tech-sector Partnerships During Two-day the highest-tech companies in one of the nation's innovation hotspots. Story Secretary's Silicon

  9. Low-Tech Education Threatens the High-Tech Future.

    ERIC Educational Resources Information Center

    Business Week, 1983

    1983-01-01

    Indicating that the quality of scientific/technical education in the United States has been slipping since the brief surge of attention in the decade following Sputnik, discusses the need for upgrading science/technical education. Includes efforts currently under way, including financial support by industry and donations of equipment and computers…

  10. Ten Top Tech Trends

    ERIC Educational Resources Information Center

    McLester, Susan

    2008-01-01

    In this article, the author discusses the major technical issues, products, and practices of the day. The top ten tech trends are listed and discussed. These include: (1) data mining; (2) cyberbullying; (3) 21st century skills; (4) digital content; (5) learning at leisure; (6) personal responders; (7) mobile tools; (8) bandwidth; (9) open-source…

  11. A Low-Tech, Hands-On Approach To Teaching Sorting Algorithms to Working Students.

    ERIC Educational Resources Information Center

    Dios, R.; Geller, J.

    1998-01-01

    Focuses on identifying the educational effects of "activity oriented" instructional techniques. Examines which instructional methods produce enhanced learning and comprehension. Discusses the problem of learning "sorting algorithms," a major topic in every Computer Science curriculum. Presents a low-tech, hands-on teaching method for sorting…

  12. 76 FR 29274 - Interstate Electronics Corp., a Subsidiary of L-3 Communications Including On-Site Leased Workers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... Resources, Systems Pros, Total Tech Services, Triple Crown Consulting, and Ingenium Technology, Inc... Resources, PDS Technical Service, Superior Technical Resources, Systems Pros, Total Tech Services, and... subject firm. The company reports that workers leased from Ingenium Technology, Inc. were employed on-site...

  13. Stability of the IMEX Methods, CNLF and BDF2-AB2, for Uncoupling Systems of Evolution Equations

    DTIC Science & Technology

    2011-02-01

    Implicit-Explicit linear multistep methods, Tech. rep., Centrum Wiskunde and Informatica (CWI) (1996). [14] W. Hundsdorfer, J. Verwer, Numerical...component splitting for the Crank-Nicolson Leap- Frog integration method, Tech. rep., Centrum Wiskunde and Informatica (CWI) (2009). [23] J. Verwer

  14. Creating Tech Wizards: Tech-Savvy Students Help Teachers Transform Practice

    ERIC Educational Resources Information Center

    Breiner, Beth

    2009-01-01

    In eastern Pennsylvania, middle schoolers are teaching the teachers how to use technology effectively in the classroom. This article describes the Technology Wizards program which was developed by the Carbon Lehigh Intermediate Unit's Department of Instructional Innovation. It is a radical departure from traditional educational professional…

  15. How Geek Became Chic

    ERIC Educational Resources Information Center

    Waters, John K.

    2008-01-01

    With budgets and staff stretched thin, schools are turning tech-savvy students into technology leaders and a popular, important source of IT support. Providing professional tech support is a very expensive a proposition, so districts from Tupelo to Greenville, and from Hattiesburg to Columbia, are enlisting students to fill the gaps. This article…

  16. Instrumentation Control Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 22 units to consider for use in a tech prep competency profile for the occupation of instrumentation control technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific…

  17. Developing Games and Simulations for Today and Tomorrow's Tech Savvy Youth

    ERIC Educational Resources Information Center

    Klopfer, Eric; Yoon, Susan

    2005-01-01

    Constructively promoting the educational development of today's young tech savvy students and fostering the productive technological facility of tomorrow's youth requires harnessing new technological tools creatively. The MIT Teacher Education Program (TEP) focuses on the research and development of educational computer-based simulations and games…

  18. Alcohol and highway safety: screening and brief intervention for alcohol problems as a community approach to improve traffic safety : traffic tech.

    DOT National Transportation Integrated Search

    2013-09-01

    The report discussed in this edition of Traffic Tech reviews the current state of knowledge : on Screening and Brief Intervention (SBI). It specifically : addresses the rationale for addressing at-risk : drinkers, defines SBI, provides examples of ho...

  19. The Virginia Tech Shootings: Implications for Crisis Communication in Educational Settings

    ERIC Educational Resources Information Center

    Barker, Gina G.; Yoder, Mollie E.

    2012-01-01

    By examining Virginia Tech's crisis communication during and after the shootings on April 16, 2007, valuable insights were gained that may be applied to current crisis communication models. This article addresses the unique characteristics of educational institutions and the need for comprehensive emergency communication strategies and on-site…

  20. Development of High-Tech Skills.

    ERIC Educational Resources Information Center

    Theuerkauf, Walter E.

    High tech systems not only generate new structures in the production process, but also involve profound changes in job organization, which in turn imply that job qualifications must be modified. In view of the changes within engineering systems and the relevant technologies, it seems expedient to choose a curricular approach based on the concepts…

  1. Tech Transfer Magazine - KSC News Volume I, Number 2, Fall/Winter 2008

    NASA Technical Reports Server (NTRS)

    Dunn, Carol (Editor)

    2008-01-01

    Kennedy Tech Transfer News is the semiannual magazine of the Innovative Partnerships Program Office at NASA Kennedy Space Center in Cape Canaveral, Florida. This magazine seeks to inform and educate cMI servant and Contractor personnel at Kennedy about actively participating in achieving NASA's technology transfer goals:

  2. Implementing a Project-Based Technology Program for High School Women.

    ERIC Educational Resources Information Center

    Boudria, Theodore J.

    2002-01-01

    Describes the successful implementation of a Women in Technology (WIT) Project-Based Learning Program in High Tech Manufacturing by the Tech Prep Consortium at Bristol Community College (Massachusetts). Reports that the program's success was mainly due to the establishment of partnerships with industry, government, and education, including area…

  3. Examination of the New Tech Model as a Holistic Democracy

    ERIC Educational Resources Information Center

    Bradley-Levine, Jill; Mosier, Gina

    2017-01-01

    Using the Degrees of Democracy Framework (Woods & Woods, 2012), we examined eight New Tech (NT) high schools to determine the extent to which they demonstrated characteristics of holistic democracy. We collected qualitative data, including observations and interviews during the fourth year of implementation. Findings indicated that the eight…

  4. The Evolution of the Georgia Tech Library Circulation Department

    ERIC Educational Resources Information Center

    Glover, Karen

    2006-01-01

    The author reviews the evolution of the Circulation Department at the Georgia Institute of Technology (Georgia Tech) Library and Information Center from 2001 to the present. It is shown how a traditional circulation department with poor customer relations transformed itself by adopting innovative policies and services leading to improved customer…

  5. Rhode Island Tech Prep Business & Industry Resource Guide.

    ERIC Educational Resources Information Center

    Community Coll. of Rhode Island, Warwick.

    This guide provides educators with information about developing partnerships with businesses. It begins with a rationale for forging education-business relationships and highlights benefits to all parties--educators, businesses, and students. The Rhode Island Tech Prep Associate Degree Program is cited as an example of how to create win-win…

  6. Curriculum Designs for Tech Prep Clusters. PACE '94.

    ERIC Educational Resources Information Center

    Schoon, Kenneth J., Ed.; Wiles, Clyde A., Ed.

    This booklet contains descriptions of various Tech Prep programs developed by PACE (Promoting Academic Excellence In Mathematics, Science & Technology for Workers of the 21st Century). Each entry includes general program descriptions, curriculum outlines, and course descriptions. The clusters and their specialty areas described in the booklet are:…

  7. Building Career Tech Programs into Career Academies

    ERIC Educational Resources Information Center

    Delano, Rick; Mittelsteadt, Sandy

    2005-01-01

    In Manatee County, Florida, not only did they build career tech programs into career academies, but they also developed an evaluation process to ensure these career academies were credible. A District Academic team created the "Documentation of Academy Assessment Criteria" with 12 core components and a rubric that helps evaluators…

  8. EARTH TECH INC.'S ENHANCED IN-SITU BIOREMEDIATION PROCESS; INNOVATIVE TECHNOLOGY EVALUATION REPORT

    EPA Science Inventory

    The USEPA conducted an evaluation of the Enhanced In-situ Bioremediation process, a biostimulation technology developed by the USDOE at the Westinghouse Savannah River Plant site in Aiken, SC. DOE has licensed the process to Earth Tech, Inc. The evaluation described in this bulle...

  9. Case Study of a Service-Learning Partnership: Montana Tech and the Montana State Prison.

    ERIC Educational Resources Information Center

    Amtmann, John; Evans, Roberta; Powers, Jack

    2002-01-01

    As a service learning project, Montana Tech students deliver a wellness program for older inmates in Montana State Prison. Outcomes identified in student interviews included improved interpersonal skills (tact, diplomacy, communication, assertiveness) and opportunities to apply knowledge. Students recognized the value of the program for…

  10. Sino-Austrian High-Tech Acupuncture Network—Annual Report 2016

    PubMed Central

    Litscher, Gerhard

    2017-01-01

    The Sino-Austrian High-Tech Acupuncture Research Network was founded in 2005 and has been growing ever since. The network comprises many partners from China and is highly involved in research and education activities. This report introduces the network’s activities in the year 2016. PMID:28930227

  11. Sino-Austrian High-Tech Acupuncture Network: Annual Report 2017

    PubMed Central

    2018-01-01

    The Sino-Austrian High-Tech Acupuncture Research Network was founded in 2005 and has been growing ever since. The network comprises many partners from China and is highly involved in research and education activities. This report introduces the network’s activities in the year 2017. PMID:29329241

  12. Loading Intensity Prediction by Velocity and the OMNI-RES 0-10 Scale in Bench Press.

    PubMed

    Naclerio, Fernando; Larumbe-Zabala, Eneko

    2017-02-01

    Naclerio, F and Larumbe-Zabala, E. Loading intensity prediction by velocity and the OMNI-RES 0-10 scale in bench press. J Strength Cond Res 32(1): 323-329, 2017-This study examined the possibility of using movement velocity and the perceived exertion as indicators of relative load in the bench press (BP) exercise. A total of 308 young, healthy, resistance trained athletes (242 men and 66 women) performed a progressive strength test up to the one repetition maximum for the individual determination of the full load-velocity and load-exertion relationships. Longitudinal regression models were used to predict the relative load from the average velocity (AV) and the OMNI-Resistance Exercise Scales (OMNI-RES 0-10 scale), considering sets as the time-related variable. Load associated with the AV and the OMNI-RES 0-10 scale value expressed after performing a set of 1-3 repetitions were used to construct 2 adjusted predictive equations: Relative load = 107.75 - 62.97 × average velocity; and Relative load = 29.03 + 7.26 × OMNI-RES 0-10 scale value. The 2 models were capable of estimating the relative load with an accuracy of 84 and 93%, respectively. These findings confirm the ability of the 2 calculated regression models, using load-velocity and load-exertion from the OMNI-RES 0-10 scale, to accurately predict strength performance in BP.

  13. Renewable Electricity Standards: Good Practices and Design Considerations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cox, Sadie; Esterly, Sean

    2016-01-02

    In widespread use globally, renewable electricity standards (RES) are one of the most widely adopted renewable energy policies and a critical regulatory vehicle to accelerate renewable energy deployment. This policy brief provides an introduction to key RES design elements, lessons from country experience, and support resources to enable more detailed and country-specific RES policy design.

  14. Postlingual adult performance in noise with HiRes 120 and ClearVoice Low, Medium, and High.

    PubMed

    Holden, Laura K; Brenner, Christine; Reeder, Ruth M; Firszt, Jill B

    2013-11-01

    The study's objectives were to evaluate speech recognition in multiple listening conditions using several noise types with HiRes 120 and ClearVoice (Low, Medium, High) and to determine which ClearVoice program was most beneficial for everyday use. Fifteen postlingual adults attended four sessions; speech recognition was assessed at sessions 1 and 3 with HiRes 120 and at sessions 2 and 4 with all ClearVoice programs. Test measures included sentences presented in restaurant noise (R-SPACE), in speech-spectrum noise, in four- and eight-talker babble, and connected discourse presented in 12-talker babble. Participants completed a questionnaire comparing ClearVoice programs. Significant group differences in performance between HiRes 120 and ClearVoice were present only in the R-SPACE; performance was better with ClearVoice High than HiRes 120. Among ClearVoice programs, no significant group differences were present for any measure. Individual results revealed most participants performed better in the R-SPACE with ClearVoice than HiRes 120. For other measures, significant individual differences between HiRes 120 and ClearVoice were not prevalent. Individual results among ClearVoice programs differed and overall preferences varied. Questionnaire data indicated increased understanding with High and Medium in certain environments. R-SPACE and questionnaire results indicated an advantage for ClearVoice High and Medium. Individual test and preference data showed mixed results between ClearVoice programs making global recommendations difficult; however, results suggest providing ClearVoice High and Medium and HiRes 120 as processor options for adults willing to change settings. For adults unwilling or unable to change settings, ClearVoice Medium is a practical choice for daily listening.

  15. Role of resilience and social support in alleviating depression in patients receiving maintenance hemodialysis

    PubMed Central

    Liu, Yueh-Min; Chang, Hong-Jer; Wang, Ru-Hwa; Yang, Li-King; Lu, Kuo-Cheng; Hou, Yi-Chou

    2018-01-01

    Background Patients who undergo hemodialysis encounter challenges including role changes, physical degeneration, and difficulty in performing activities of daily living (ADLs) and self-care. These challenges deteriorate their physiological and psychosocial conditions, resulting in depression. High resilience (RES) and social support can alleviate stress and depression. This study evaluated the importance of RES and social support in managing depression in elderly patients undergoing maintenance hemodialysis (HD). Patients and methods In this descriptive, correlational study, 194 older patients undergoing HD were enrolled from the HD centers of three hospitals in northern Taiwan. The Barthel ADL Index, RES scale, Inventory of Socially Supportive Behavior, and Beck Depression Inventory-II were used. Hierarchical regression analysis was applied to evaluate the interaction of RES and social support with illness severity, demographics, and ADLs. Results Of the total participants, 45.9% experienced depressive symptoms. Demographic analysis showed that men and those with high educational level and income and financial independence had less depression (p<0.01). Patients with a higher Barthel Index (n=103), RES scale (n=33), and social support (n=113) showed less depressive symptoms (p<0.01). We found a significant negative correlation between depressive symptoms and social support (r=−0.506, p<0.01) and RES (r=−0.743, p<0.01). Hierarchical regression analysis showed that RES could buffer the effects of symptom severity on depression (b=−0.436, p<0.01), but social support did not exert a buffering effect. Conclusion The severity of illness symptoms and ADLs were the major determinants of depressive symptoms. High RES could alleviate depressive symptoms in the older patients undergoing HD. PMID:29535526

  16. Immunomodulatory effects of high-protein diet with resveratrol supplementation on radiation-induced acute-phase inflammation in rats.

    PubMed

    Kim, Kyoung-Ok; Park, HyunJin; Chun, Mison; Kim, Hyun-Sook

    2014-09-01

    We hypothesized that a high-protein diet and/or resveratrol supplementation will improve acute inflammatory responses in rats after receiving experimental abdominal radiation treatment (ART). Based on our previous study, the period of 10 days after ART was used as an acute inflammation model. Rats were exposed to a radiation dose of 17.5 Gy and were supplied with a control (C), 30% high-protein diet (HP), resveratrol supplementation (RES), or HP with RES diet ([HP+RES]). At day 10 after ART, we measured profiles of lipids, proteins, and immune cells in blood. The levels of clusters of differentiating 4(+) (CD4(+)) cells and regulatory T cells, serum proinflammatory cytokines, and 8-hydroxy-2'-deoxyguanosine (8-OHdG) in urine were also measured. ART caused significant disturbances of lipid profiles by increasing triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C), and decreasing high-density lipoprotein cholesterol. The proinflammatroy cytokine levels were also increased by ART. All the experimental diets (HP, RES, and [HP+RES]) significantly decreased levels of TG, monocytes, proinflammatory cytokines, and 8-OHdG, whereas the platelet counts were increased. In addition, the HP and [HP+RES] diets decreased the concentrations of plasma LDL-C and total cholesterol. Also, the HP and RES diets decreased regulatory T cells compared with those of the control diet in ART group. Further, the HP diet led to a significant recovery of white blood cell counts, as well as increased percentages of lymphocyte and decreased percentages of neutrophils. In summary, RES appeared to be significantly effective in minimizing radiation-induced damage to lipid metabolism and immune responses. Our study also demonstrated the importance of dietary protein intake in recovering from acute inflammation by radiation.

  17. A regulatory network to segregate the identity of neuronal subtypes.

    PubMed

    Lee, Seunghee; Lee, Bora; Joshi, Kaumudi; Pfaff, Samuel L; Lee, Jae W; Lee, Soo-Kyung

    2008-06-01

    Spinal motor neurons (MNs) and V2 interneurons (V2-INs) are specified by two related LIM-complexes, MN-hexamer and V2-tetramer, respectively. Here we show how multiple parallel and complementary feedback loops are integrated to assign these two cell fates accurately. While MN-hexamer response elements (REs) are specific to MN-hexamer, V2-tetramer-REs can bind both LIM-complexes. In embryonic MNs, however, two factors cooperatively suppress the aberrant activation of V2-tetramer-REs. First, LMO4 blocks V2-tetramer assembly. Second, MN-hexamer induces a repressor, Hb9, which binds V2-tetramer-REs and suppresses their activation. V2-INs use a similar approach; V2-tetramer induces a repressor, Chx10, which binds MN-hexamer-REs and blocks their activation. Thus, our study uncovers a regulatory network to segregate related cell fates, which involves reciprocal feedforward gene regulatory loops.

  18. Recycling Endosomes of Polarized Epithelial Cells Actively Sort Apical and Basolateral Cargos into Separate Subdomains

    PubMed Central

    Thompson, Anthony; Nessler, Randy; Wisco, Dolora; Anderson, Eric; Winckler, Bettina

    2007-01-01

    The plasma membranes of epithelial cells plasma membranes contain distinct apical and basolateral domains that are critical for their polarized functions. However, both domains are continuously internalized, with proteins and lipids from each intermixing in supranuclear recycling endosomes (REs). To maintain polarity, REs must faithfully recycle membrane proteins back to the correct plasma membrane domains. We examined sorting within REs and found that apical and basolateral proteins were laterally segregated into subdomains of individual REs. Subdomains were absent in unpolarized cells and developed along with polarization. Subdomains were formed by an active sorting process within REs, which precedes the formation of AP-1B–dependent basolateral transport vesicles. Both the formation of subdomains and the fidelity of basolateral trafficking were dependent on PI3 kinase activity. This suggests that subdomain and transport vesicle formation occur as separate sorting steps and that both processes may contribute to sorting fidelity. PMID:17494872

  19. Renewable energy sources in Bulgaria: Current state and trends

    NASA Astrophysics Data System (ADS)

    Kolev, K.

    The over-dependency of Bulgaria on imported fuel stressed the importance of developing a new energy strategy based on energy saving which includes also using renewable energy sources (RES). The target is the substitution of at least 2 percent of the real primary energy consumption with RES by 2010. The author gives a generalized analysis of the available RES in Bulgaria -solar, wind, geothermal, biomass and mini-hydraulic. The potentialities of each source for its usage as a suitable energy supply are pointed out, as well as the current status of research and implementation work, problems connected with legislation, financing and production of particular facilities. The governmental policy concerning RES is considered briefly. A description is given to the project 'Technical and Economical Assessment of Possibilities for Expansion of the RES-part in the Energy Balance of the Country' developed and started in 1994 in the framework of the PHARE program.

  20. [Comparison of the accuracy of rectal endoscopic sonography and magnetic resonance imaging in the diagnosis of colorectal endometriosis].

    PubMed

    Kanté, F; Belghiti, J; Roseau, G; Thomassin-Naggara, I; Bazot, M; Daraï, E; Ballester, M

    2017-03-01

    To compare the accuracy of magnetic resonance imaging (MRI) and rectal endoscopic sonography (RES) for the diagnosis of colorectal endometriosis. In retrospective study, 407 patients operated on service of gynecology of Tenon hospital for deep endometriosis with suspected colorectal involvement. All patients underwent MRI and then RES. In the study, 239 patients (59%) had colorectal endometriosis which were diagnosed with the histology. The sensitivity, specificity, positive and negative predictive value (PPV and NPV) of RES and MRI for the diagnosis of colorectal endometriosis were respectively 92%, 87%, 91%, 88% and 85%, 88%, 91%, 80%. The accuracy of RES was not significantly different than MRI (90% versus 86%, P=0.09). RES is a good exam to diagnose colorectal endometriosis. It is able to improve diagnosis performances. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Binding of resveratrol with sodium caseinate in aqueous solutions.

    PubMed

    Acharya, Durga P; Sanguansri, Luz; Augustin, Mary Ann

    2013-11-15

    The interaction between resveratrol (Res) and sodium caseinate (Na-Cas) has been studied by measuring fluorescence quenching of the protein by resveratrol. Quenching constants were determined using Stern-Volmer equation, which suggests that both dynamic and static quenching occur between Na-Cas and Res. Binding constants for the complexation between Na-Cas and Res were determined at different temperatures. The large binding constants (3.7-5.1×10(5)M(-1)) suggest that Res has strong affinity for Na-Cas. This affinity decreases as the temperature is raised from 25 to 37°C. The binding involves both hydrogen bonding and hydrophobic interaction, as suggested by negative enthalpy change and positive entropy change for the binding reaction. The present study indicates that Na-Cas, a common food protein, may be used as a carrier of Res, a bioactive polyphenol which is insoluble in both water and oils. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Hypergol Maintenance Facility Hazardous Waste South Staging Areas, SWMU 070 Corrective Measures Implementation

    NASA Technical Reports Server (NTRS)

    Miller, Ralinda R.

    2016-01-01

    This document presents the Corrective Measures Implementation (CMI) Year 10 Annual Report for implementation of corrective measures at the Hypergol Maintenance Facility (HMF) Hazardous Waste South Staging Areas at Kennedy Space Center, Florida. The work is being performed by Tetra Tech, Inc., for the National Aeronautics and Space Administration (NASA) under Indefinite Delivery Indefinite Quantity (IDIQ) NNK12CA15B, Task Order (TO) 07. Mr. Harry Plaza, P.E., of NASA's Environmental Assurance Branch is the Remediation Project Manager for John F. Kennedy Space Center. The Tetra Tech Program Manager is Mr. Mark Speranza, P.E., and the Tetra Tech Project Manager is Robert Simcik, P.E.

  3. The Value of "Experience" and the labour market entry of new immigrants to Canada.

    PubMed

    Hall, Peter V; Sadouzai, Tulin

    2010-01-01

    We use data from three waves of the Longitudinal Survey of Immigrants to Canada to compare how pre-immigration experience in hi-tech and regulated occupations affects employment outcomes. While differences do decline over time, those with experience in an unregulated hi-tech occupation are more likely to be employed sooner in a matching and/or full time job. Immigrants with hi-tech occupational experience are more likely to have their foreign experience accepted, possibly due to the transferability of these skills and the absence of institutional barriers. These findings indicate important sectoral, regulatory, and institutional differences in the treatment of pre-immigration experience, with policy implications.

  4. Future Assets, Student Talent (FAST)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Future Assets, Student Talent (FAST) motivates and prepares talented students with disabilities to further their education and achieve High Tech and professional employment. The FAST program is managed by local professionals, business, and industry leaders; it is modeled after High School High Tech project TAKE CHARGE started in Los Angeles in 1983. Through cooperative efforts of Alabama Department of Education, Vocational Rehabilitation, Adult and Children Services, and the President's Committee on Employment of People with Disabilities, north central Alabama was chosen as the second site for a High School High Tech project. In 1986 local business, industry, education, government agencies, and rehabilitation representatives started FAST. The program objectives and goals, results and accomplishments, and survey results are included.

  5. Transforming the Classroom. Technology Counts, 2016. Education Week. Volume 35, Issue 35

    ERIC Educational Resources Information Center

    Edwards, Virginia B., Ed.

    2016-01-01

    The 2016 edition of "Education Week's" long-­running "Technology Counts" report combines in-depth reporting and insight from an original national survey to reveal teachers' confidence levels in ed tech, how teachers approach integrating technology into the classroom, and decision-making behind tech products. Contents include:…

  6. Reformulating General Engineering and Biological Systems Engineering Programs at Virginia Tech

    ERIC Educational Resources Information Center

    Lohani, Vinod K.; Wolfe, Mary Leigh; Wildman, Terry; Mallikarjunan, Kumar; Connor, Jeffrey

    2011-01-01

    In 2004, a group of engineering and education faculty at Virginia Tech received a major curriculum reform and engineering education research grant under the department-level reform (DLR) program of the NSF. This DLR project laid the foundation of sponsored research in engineering education in the Department of Engineering Education. The DLR…

  7. Iowa's Tech Prep Model: Issues/Model Components/"Patterns of Evidence." Revised.

    ERIC Educational Resources Information Center

    North Iowa Area Community Coll., Mason City.

    Developed by the Iowa Department of Education, North Iowa Area Community College, and Hawkeye Community College (Iowa), this booklet presents the tech prep model for articulation efforts among all educational entities, business, industry, labor, and communities in Iowa. Following a list of committee members working on the model and graphs of the…

  8. Low Tech Solutions: A Place To Begin.

    ERIC Educational Resources Information Center

    Ensign, Arselia S., Ed.

    1992-01-01

    This guide presents low tech solutions that have worked for some people with disabilities or their parents. Twenty-one ideas are offered to give children with physical disabilities more opportunities for play and art. Examples include recycling stuffed animals into puppets, punching a hole in top of playing cards to accommodate a mouth stick, and…

  9. Individualized Math Problems in Percent. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This volume includes problems concerned with computing percents.…

  10. Individualized Math Problems in Algebra. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic, and contains problems related to diverse vocations. Solutions are provided for all problems. Problems presented in this package concern ratios used in food…

  11. Individualized Math Problems in Fractions. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This package contains problems involving computation with common…

  12. Individualized Math Problems in Geometry. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. The volume contains problems in applied geometry. Measurement of…

  13. ADOPT: Automotive Deployment Options Projection Tool | Transportation

    Science.gov Websites

    new model options by combining high-selling powertrains and high-selling vehicle platforms. NREL has . Screenshot of the ADOPT user interface, with two simulation scenario options (low tech and high tech emissions. Biomass Market Dynamics Supporting the Large-Scale Deployment of High-Octane Fuel Production in

  14. Computer-Based Cognitive Tools in Teacher Training: The COG-TECH Projects

    ERIC Educational Resources Information Center

    Orhun, Emrah

    2003-01-01

    The COG-TECH (Cognitive Technologies for Problem Solving and Learning) Network conducted three international projects between 1994 and 2001 under the auspices of the European Commission. The main purpose of these projects was to train teacher educators in the Mediterranean countries to use computers as effective pedagogical tools. The summer…

  15. Relationship of Technology Education to Tech Prep.

    ERIC Educational Resources Information Center

    Anderson, Lowell D.

    With increased global competition, it is imperative that secondary school programs be reformed so as to be able to turn out productive workers having basic skills in reading, writing, and mathematics and the ability to solve problems and learn new information. One proposed reform, tech prep, can be defined as a technical education alternative to…

  16. 76 FR 14099 - Quad Tech, Inc., Sussex, WI; Notice of Affirmative Determination Regarding Application for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... dated February 7, 2011, a worker requested administrative reconsideration of the negative determination regarding workers' eligibility to apply for Trade Adjustment Assistance (TAA) applicable to workers and former workers of Quad Tech, Inc., Sussex, Wisconsin (TA-W-73,441A) (subject firm). The determination was...

  17. Hartford Hospital surgeons share publicity with robot 'assistants.'.

    PubMed

    Botvin, Judith D

    2004-01-01

    Hartford Hospital, Hartford, Conn. finds some patients gravitate to Boston or New York City for high-tech procedures. Being the first Connecticut hospital with the daVinci Robotic Surgery System, it developed an advertising campaign emphasizing high-tech surgery with the human touch. Hartford also broadcast a robotic prostatectomy on its popular live webcast series.

  18. Blueprint for Safer Campuses

    ERIC Educational Resources Information Center

    Thrower, Raymond H.; Healy, Steven J.; Lynch, Michael; Margolis, Gary J.; Stafford, Dolores; Taylor, William

    2009-01-01

    The impact of the rampage shootings at Virginia Tech on April 16, 2007 continues to be felt across the U.S. and the world. Clearly this incident, along with other active shooter incidents that have occurred since the Virginia Tech tragedy, has impacted one's awareness of campus safety and security. A number of states, other governmental entities,…

  19. Teacher Development Program for ATP 2000. Project Report.

    ERIC Educational Resources Information Center

    Sutphin, Dean; And Others

    Agri Tech Prep 2000 (ATP 2000) is a 4-year tech prep program linking high school and postsecondary curricula designed to prepare New York students for careers in agriculture or acceptance into a college program in agriculture. Because teacher development was designated an integral project component for fiscal year 1991-1992, a weeklong teacher…

  20. Educating Silicon Valley: Corporate Education Reform and the Reproduction of the Techno-Economic Revolution

    ERIC Educational Resources Information Center

    Williamson, Ben

    2017-01-01

    Silicon Valley's high-tech companies, tech-philanthropists, startups, and culture of venture capital are "the centre of a techno-economic revolution" that is "now spreading outwards across the world, with major societal effects and implications" (Duff 2016, 5). In this article, Ben Williamson traces and maps how education is…

  1. Update on Research and Leadership, 2002.

    ERIC Educational Resources Information Center

    Barnett, Elisabeth, Ed.

    2002-01-01

    This issue (v14 n1) of the University of Illinois'"On Research and Leadership Update" contains seven articles. The first, "Community College and Beyond: A National Evaluation of Tech Prep," by Debra Bragg, discusses results of the author's study of student experiences and outcomes in eight local tech-prep consortia in the U.S.…

  2. Twitter Chats: Connect, Foster, and Engage Internal Extension Networks

    ERIC Educational Resources Information Center

    Seger, Jamie; Hill, Paul; Stafne, Eric; Swadley, Emy

    2017-01-01

    The eXtension Educational Technology Learning Network (EdTechLN) has found Twitter to be an effective form of informal communication for routinely engaging network members. Twitter chats provide Extension professionals an opportunity to reach and engage one other. As the EdTechLN's experimentation with Twitter chats has demonstrated, the use of…

  3. Individualized Math Problems in Measurement and Conversion. Oregon Vo-Tech Mathematics Problem Sets.

    ERIC Educational Resources Information Center

    Cosler, Norma, Ed.

    This is one of eighteen sets of individualized mathematics problems developed by the Oregon Vo-Tech Math Project. Each of these problem packages is organized around a mathematical topic and contains problems related to diverse vocations. Solutions are provided for all problems. This volume includes problems involving measurement, computation of…

  4. High Tech and the Upward Mobility of Non-Technical People.

    ERIC Educational Resources Information Center

    Kammire, Linda L.

    The social and psychological effects of rapid technological advancement in the computer industry is the subject of this paper, which focuses on the concerns of people with non-technical backgrounds. It describes the career series, High Tech for Non-Technical People, created by the Georgia State University Career Development Center. The three…

  5. Give Your Old-School Curriculum a NETS Makeover

    ERIC Educational Resources Information Center

    LaMaster, Jen

    2012-01-01

    Integrating digital age technology into an industrial age educational system is hard enough. Imagine introducing ed tech to a 450-year-old Jesuit educational paradigm. Find out how to seamlessly combine the NETS with a centuries-old framework to create an effective ed tech strategic plan. This article describes how the author successfully…

  6. Community College Professional Development: Sharing What Works. Proceedings of a National Conference (San Antonio, Texas, October 18-19, 1991).

    ERIC Educational Resources Information Center

    Faulkner, Susan L.; And Others

    This document contains 30 papers on professional development in community colleges. The following papers are included: "Effective Leadership Strategies for Planning and Implementing Tech Prep" (Bragg, Huffman); "Small Business Management-Tech Prep" (Harvey); "Educational Reform and the New Mission" (Hoerner);…

  7. Tech Prep II: Implementation Final Report.

    ERIC Educational Resources Information Center

    Brown, Jane A.

    This document contains the final progress report on a tech prep implementation project and the Work Force Challenge 2000 Report developed during the project. The final report lists these major accomplishments: approximately 1,500 educators in grades K-12 were provided information concerning future global issues in the work force and the effects in…

  8. From High School to College to Work: Students with Disabilities in High Tech Fields.

    ERIC Educational Resources Information Center

    Burgstahler, Sheryl; Wild, Nellie; Smallman, Julie

    This paper describes DO-IT (Disabilities, Opportunities, Internetworking and Technology), a cooperative program of the University of Washington and the High School/High Tech program to increase the career success of individuals with disabilities by providing access to technology, career preparation activities, and work experiences. DO-IT works…

  9. Human Resource Blueprints in Irish High-Tech Start-Up Firms

    ERIC Educational Resources Information Center

    Keating, Mary A.; Olivares, Mariabrisa

    2006-01-01

    Focusing on Irish high-tech start-ups, this paper reports on the results of an empirical study of organization building by entrepreneurial firms, specifically in relation to human resource practices. The research findings are benchmarked with findings from SPEC, the Stanford Project of Emerging Companies (Baron and Hannan, 2002). Human resources…

  10. Innovation Engine

    ERIC Educational Resources Information Center

    Stuart, Reginald

    2012-01-01

    This article describes how Wayne State University's TechTown is helping revive Detroit's hard-hit economy. TechTown got its start when then-Wayne State President Irvin Reid and a small group of business leaders in the city and state officials decided Detroit needed to embrace the business incubator idea that had been so successful in other regions…

  11. Future of Autonomous Ground Logistics: Convoys in the Department of Defense

    DTIC Science & Technology

    2011-02-13

    Driverless van crosses from Europe to Asia, CNN, October 27, 2010, http://edition.cnn.com/2010/TECH/innovation/10/27/driverless.car/ (accessed November 13...accessed March 13, 2011). Kent, Jo Ling. “ Driverless Van Crosses from Europe to Asia,” CNN, October 27, 2010. http://edition.cnn.com/2010/TECH

  12. Restructuring Student Experiences Using Tech Prep Mapping To Integrate Vocational and Academic Curriculum.

    ERIC Educational Resources Information Center

    Pirozzoli, Don

    The growing emphasis on accountability and the demand for better prepared students is pressing institutions of higher education to examine restructuring. Student experiences represent an important arena for school restructuring, and a useful approach to changing student experiences is the Tech Prep Mapping (TPM) process. The TPM process requires…

  13. Is Education Facing a "Tech Bubble"?

    ERIC Educational Resources Information Center

    Davis, Michelle R.

    2013-01-01

    Educational technology companies and entrepreneurs may face the risk of a "tech bubble," similar to the massive boom-and-bust that rocked the technology market in the late 1990s, according to market analysts and a recently released paper. A relatively new focus on K-12 educational technology as an investment vehicle, a surge of investors looking…

  14. Job Future's Bright for the Chefs of Muskingum Tech.

    ERIC Educational Resources Information Center

    Hoffman, Carl

    1993-01-01

    A two-year culinary arts program at Muskingum College (Zanesville, Ohio) prepares students for jobs in an emerging service-based economy. Students receive intensive classroom instruction and hands-on learning in a high-tech kitchen. Twenty-five full-time and 12 part-time students are completing their first year in the program. (LP)

  15. 76 FR 51432 - The Boeing Company; Amended Certification Regarding Eligibility To Apply for Worker Adjustment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Internatinal Corp, Comsys, Filter LLC, Excell, Entegee, Chipton-Ross, Ian Martin, Can-Tech, IT Services, IDEX... Internatinal Corp, Comsys, Filter LLC, Excell, Entegee, Chipton-Ross, Ian Martin, Can-Tech, IT Services, IDEX..., Inconen, CTS, Hi-Tec, Woods, Ciber, Kelly Services, Analysts International Corp, Comsys, Filter LLC...

  16. The Road to Lasting Tech Leadership

    ERIC Educational Resources Information Center

    Luthra, Shabbi; Fochtman, Paul

    2011-01-01

    As with many schools, tech integration at the American School of Bombay (ASB) was varied and scattered. ASB had enthusiastic teachers who used technology in class, but they were the exception. As a result, just a small percentage of students experienced new ways of learning. The authors wanted to turn the occasional use of technology into a…

  17. Engaging Students in STEM Careers with Project-Based Learning--MarineTech Project

    ERIC Educational Resources Information Center

    Verma, Alok K.; Dickerson, Daniel; McKinney, Sue

    2011-01-01

    Old Dominion University and Norfolk State University, in collaboration with the marine industry and local school systems, is improving STEM preparation using innovative experiences for students and teachers in the nation's major shipbuilding and repair areas through MarineTech and SBRCD (Shipbuilding Repair and Maritime Career Day) projects. The…

  18. Tragedy at Virginia Tech: Trauma and Its Aftermath

    ERIC Educational Resources Information Center

    Flynn, Christopher; Heitzmann, Dennis

    2008-01-01

    While college campuses are relatively safe environments, the promise of safety and security on campus was shattered by a single gunman on April 16, 2007. Seung-Hui Cho, a senior at Virginia Tech, shot 49 students and faculty, killing 32, before killing himself. The authors are psychologists and directors of university counseling centers; they…

  19. A Dialogue with the Original Curriculum Basher about Tech Prep and a Liberal Education.

    ERIC Educational Resources Information Center

    Roth, Gene L.

    1992-01-01

    An imaginary dialogue with Socrates elicits premises about tech prep: (1) it is not narrow vocationalism or anomalous to liberal education; (2) by blending academic and vocational content, it emulates liberal education purposes; (3) critical thinking skills must be fostered; and (4) meaningful cross-disciplinary integration is vital. (SK)

  20. Report on Virginia Tech Shootings Urges Clarification of Privacy Laws

    ERIC Educational Resources Information Center

    Fischer, Karin

    2007-01-01

    Educators, mental-health officials, and law-enforcement officers often do not share information about troubled students because they are confused by what they can disclose under complex and overlapping privacy laws, according to a report on the Virginia Tech shootings. Attorney General Alberto R. Gonzales and two other Bush cabinet secretaries…

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