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Sample records for middle east water

  1. Water Resource Conflicts in the Middle East.

    ERIC Educational Resources Information Center

    Drake, Christine

    1997-01-01

    Analyzes the causes and conditions of the major sources of conflict concerning the three major international river basins in the Middle East: the Tigris-Euphrates, the Nile, and the Jordan-Yarmuk. Investigates possible solutions. Includes maps and population statistics of the major countries involved in the conflict. (MJP)

  2. Middle East

    SciTech Connect

    Hemer, D.O.; Mason, J.F.; Hatch, G.C.

    1981-10-01

    Petroleum production in Middle East countries during 1980 totaled 6,747,719,000 bbl or an average rate of 18,436,390,000 bbl/d, down 13.9% from 1979. Increases were in Saudi Arabia and Syria. Significant decreases occurred in Iraq, Iran, Kuwait, and Turkey. New discoveries were made in Abu Dhabi, Iran, Saudi Arabia, Sharjah, and Oman. New areas were explored in Bahrain, Oman, Syria, and Yemen. 9 figures, 16 tables.

  3. Water in the Middle East, a Secondary and College Level Multi-Media Study.

    ERIC Educational Resources Information Center

    Manneberg, Eliezer

    The secondary and college level guide outlines a course of study on the Middle East, with emphasis on water problems of the area. Among the course objectives are the following: (1) make generalizations about particular Middle Eastern cultures and support them with evidence; (2) interpret environmental and social data from specific Middle Eastern…

  4. Water management in Africa and the Middle East, challenges and opportunities

    SciTech Connect

    Brooks, D.B.; Rached, E.; Rathgeber, E.

    1996-11-01

    This publication presents proceedings and contributed papers from a workshop held to determine the present water supply situation in Africa and the Middle East and to gain a better understanding of the opinions and priorities that should be taken into consideration when setting strategies for sustainable water management. The first three papers are overviews of key water issues: Demand-side management, conservation, and efficiency; allocation of water resources; the roles of women and men in water resource management in Africa. These are followed by eleven contributions on water management in various sub-regions of Africa and the Middle East.

  5. The Middle East.

    ERIC Educational Resources Information Center

    Blouin, Virginia; And Others

    This sixth grade resource unit focuses on Middle East culture as seen through five areas of the social sciences: anthropology-sociology, geography, history, economics, and political science. Among objectives that the student is expected to achieve are the following: 1) given general information on the Middle East through the use of film, visuals,…

  6. Optimal water management and conflict resolution: The Middle East Water Project

    NASA Astrophysics Data System (ADS)

    Fisher, Franklin M.; Arlosoroff, Shaul; Eckstein, Zvi; Haddadin, Munther; Hamati, Salem G.; Huber-Lee, Annette; Jarrar, Ammar; Jayyousi, Anan; Shamir, Uri; Wesseling, Hans

    2002-11-01

    In many situations, actual water markets will not allocate water resources optimally, largely because of the perceived social value of water. It is possible, however, to build optimizing models which, taking account of demand as well as supply considerations, can substitute for actual markets. Such models can assist the formation of water policies, taking into account user-supplied values and constraints. They provide powerful tools for the system-wide cost-benefit analysis of infrastructure; this is illustrated by an analysis of the need for desalination in Israel and the cost and benefits of adding a conveyance line. Further, the use of such models can facilitate cooperation in water, yielding gains that can be considerably greater than the value of the disputed water itself. This can turn what appear to be zero-sum games into win-win situations. The Middle East Water Project has built such a model for the Israeli-Jordanian-Palestinian region. We find that the value of the water in dispute in the region is very small and the possible gains from cooperation are relatively large. Analysis of the scarcity value of water is a crucial feature.

  7. Water and Land Limitations to Future Agricultural Production in the Middle East

    NASA Astrophysics Data System (ADS)

    Koch, J. A. M.; Wimmer, F.; Schaldach, R.

    2015-12-01

    Countries in the Middle East use a large fraction of their scarce water resources to produce cash crops, such as fruit and vegetables, for international markets. At the same time, these countries import large amounts of staple crops, such as cereals, required to meet the nutritional demand of their populations. This makes food security in the Middle East heavily dependent on world market prices for staple crops. Under these preconditions, increasing food demand due to population growth, urban expansion on fertile farmlands, and detrimental effects of a changing climate on the production of agricultural commodities present major challenges to countries in the Middle East that try to improve food security by increasing their self-sufficiency rate of staple crops.We applied the spatio-temporal land-use change model LandSHIFT.JR to simulate how an expansion of urban areas may affect the production of agricultural commodities in Jordan. We furthermore evaluated how climate change and changes in socio-economic conditions may influence crop production. The focus of our analysis was on potential future irrigated and rainfed production (crop yield and area demand) of fruit, vegetables, and cereals. Our simulation results show that the expansion of urban areas and the resulting displacement of agricultural areas does result in a slight decrease in crop yields. This leads to almost no additional irrigation water requirements due to the relocation of agricultural areas, i.e. there is the same amount of "crop per drop". However, taking into account projected changes in socio-economic conditions and climate conditions, a large volume of water would be required for cereal production in order to safeguard current self-sufficiency rates for staple crops. Irrigation water requirements are expected to double until 2025 and to triple until 2050. Irrigated crop yields are projected to decrease by about 25%, whereas there is no decrease in rainfed crop yields to be expected.

  8. Understanding the Middle East.

    ERIC Educational Resources Information Center

    Owen, Evelyn C.

    This nine-week unit on the Middle East for sixth graders was developed as part of a series by the Public Education Religion Studies Center at Wright State University. A major objective is to help students understand and appreciate sacred times and sacred places within this cultural setting. They learn how beliefs and practices cause the people to…

  9. Middle East Respiratory Syndrome (MERS)

    MedlinePlus

    Middle East Respiratory Syndrome Coronavirus; MERS-CoV; Novel coronavirus; nCoV ... Centers for Disease Control and Prevention. Middle East Respiratory Syndrome (MERS): Frequently Asked Questions and Answers. Updated ...

  10. Progressive development of water resources in the Middle East for sustainable water supply in a period of climate change.

    PubMed

    Issar, Arie S; Adar, Eilon

    2010-11-28

    The history of the Middle East has been influenced by past global climatic changes. Warm periods caused droughts, resulting in desertification, migration and war. Cold periods were humid and brought prosperity and agricultural settlement to the desert fringes. The forecast based on this correlation is that the present global warming will cause the drying up of the Middle East. As in the past, this negative impact should be mitigated by using the groundwater resources stored from past wetter times. This will involve deep drilling, pumping and modern irrigation methods within the framework of a new policy of 'progressive development', which will entail the use of currently undeveloped natural water resources beyond that of present water replenishment. While the use of the one-time groundwater reserves is taking place, a master long-term comprehensive progressive development plan for the Middle East will be prepared. This plan will include the step-by-step development of other water resources such as treated effluents, desalinated brackish groundwater and desalination of seawater. PMID:20956375

  11. Progressive development of water resources in the Middle East for sustainable water supply in a period of climate change.

    PubMed

    Issar, Arie S; Adar, Eilon

    2010-11-28

    The history of the Middle East has been influenced by past global climatic changes. Warm periods caused droughts, resulting in desertification, migration and war. Cold periods were humid and brought prosperity and agricultural settlement to the desert fringes. The forecast based on this correlation is that the present global warming will cause the drying up of the Middle East. As in the past, this negative impact should be mitigated by using the groundwater resources stored from past wetter times. This will involve deep drilling, pumping and modern irrigation methods within the framework of a new policy of 'progressive development', which will entail the use of currently undeveloped natural water resources beyond that of present water replenishment. While the use of the one-time groundwater reserves is taking place, a master long-term comprehensive progressive development plan for the Middle East will be prepared. This plan will include the step-by-step development of other water resources such as treated effluents, desalinated brackish groundwater and desalination of seawater.

  12. Improving water use in agriculture. Experiences in the Middle East and North Africa

    SciTech Connect

    Tuijl, W.V.

    1993-08-01

    As water becomes more scarce, many countries are under pressure to conserve water, especially in the agricultural sector. This paper examines strategies that save water in river basins, irrigation projects, and on farms throughout the Middle East and North Africa. Countries elsewhere can use these suggestions in their own water conservation strategies. Improved surface irrigation techniques and micro-irrigation systems are evaluated. These systems use sprinkler, drip/trickle, or micro-spray methods. The author reviews the preliminary work that is needed to install modern irrigation technologies. He describes the role that governments must play to improve the infrastructure and institutions that affect water use. He also provides detailed case studies of efficient irrigation practices in Cyprus, Israel, and Jordan. These case studies describe the conditions that made better irrigation technology a necessity. They look at ways to plan for development, management, and utilization of water in the face of growing demand. Key topics include how to oversee water rights, adopt essential land reforms, and install a graduated system of water pricing and allocation. The study also recommends projects in water conservation and research.

  13. Virtual industrial water usage and wastewater generation in the Middle East/North African region

    NASA Astrophysics Data System (ADS)

    Sakhel, S. R.; Geissen, S.-U.; Vogelpohl, A.

    2013-01-01

    This study deals with the quantification of volumes of water usage, wastewater generation, virtual water export, and wastewater generation from export for eight export relevant industries present in the Middle East/North Africa (MENA). It shows that about 3400 million m3 of water is used per annum while around 793 million m3 of wastewater is generated from products that are meant for domestic consumption and export. The difference between volumes of water usage and wastewater generation is due to water evaporation or injecting underground (oil wells pressure maintenance). The wastewater volume generated from production represents a population equivalent of 15.5 million in terms of wastewater quantity and 30.4 million in terms of BOD. About 409 million m3 of virtual water flows from MENA to EU27 (resulting from export of eight commodities) which is equivalent to 12.1% of the water usage of those industries and Libya is the largest virtual water exporter (about 87 million m3). Crude oil and refined petroleum products represent about 89% of the total virtual water flow, fertilizers represent around 10% and 1% remaining industries. EU27 poses the greatest indirect pressure on the Kuwaiti hydrological system where the virtual water export represents about 96% of the actual renewable water resources in this country. The Kuwaiti crude oil water use in relation to domestic water withdrawal is about 89% which is highest among MENA countries. Pollution of water bodies, in terms of BOD, due to production is very relevant for crude oil, slaughterhouses, refineries, olive oil, and tanneries while pollution due to export to EU27 is most relevant for crude oil industry and olive oil mills.

  14. The politics of assessment: water and sanitation MDGs in the Middle East.

    PubMed

    Zawahri, Neda; Sowers, Jeannie; Weinthal, Erika

    2011-01-01

    The Middle East and North Africa (MENA) is generally considered to be making adequate progress towards meeting Target 10 of the Millennium Development Goals (MDGs), which calls for halving the proportion of the population with inadequate access to drinking water and sanitation. Progress towards achieving Target 10 is evaluated by the Joint Monitoring Programme (JMP), run by UNICEF and WHO. This article shows that the assessment methodologies employed by the JMP significantly overstate coverage rates in the drinking water and sanitation sectors, by overlooking and ‘not counting’ problems of access, affordability, quality of service and pollution. The authors show that states in MENA often fail to provide safe drinking water and adequate sanitation services, particularly in densely populated informal settlements, and that many centralized water and sanitation infrastructures contribute to water pollution and contamination. Despite the glaring gap between the MDG statistics and the evidence available from national and local reports, exclusionary political regimes in the region have had few incentives to adopt more accurate assessments and improve the quality of service. While international organizations have proposed some reforms, they too lack incentives to employ adequate measures that gauge access, quality and affordability of drinking water and sanitation services.

  15. Modeling drought variability in the water scarce Middle East and Southwest Asia

    NASA Astrophysics Data System (ADS)

    Barlow, Mathew; Hoell, Andrew; Schubert, Siegfried; Wang, Hailan

    2016-04-01

    The ability to simulate drought variability across the water scarce Middle East and Southwest Asia [40-80E,10-45N] is examined in terms of the seasonal precipitation variability simulated in a suite of different atmospheric models forced with observed sea surface temperatures. Several, but not all, of the models are able to capture key circulation changes known to be associated with large-scale forcing of severe drought in the region. Simulation skill also varies across the region. The model differences and skill areas have important implications for seasonal prediction of regional drought, which is explored both in general and for specific regional drought events, including 1999-2001, 2007-2008, and 2014-2015. The societal impact of the drought variability is considered in terms of the occurrence of drought disasters, as recorded in the CRED EM-DAT database.

  16. Bilharziasis control in relation to water resources development in Africa and the Middle East

    PubMed Central

    McMullen, Donald B.; Buzo, Z. J.; Rainey, Marshall B.; Francotte, Jean

    1962-01-01

    As part of its world-wide programme for the control of bilharziasis, the World Health Organization has set up a Bilharziasis Advisory Team, composed of an epidemiologist and an engineer, to investigate in different countries the prevalence of the disease and its relationship to irrigation, agriculture and a variety of factors associated with the development of water resources. This paper is an appraisal of the situation in 15 countries in Africa and the Middle East, based largely on surveys conducted by the Bilharziasis Advisory Team in the period 1958-60. Analyses of data from these 15 countries indicate that about 26 million people, out of a total population of 107 million, have bilharziasis. In spite of considerable expenditure on control measures, the prevalence of the disease is increasing. This trend is closely related to water resources development. On the basis of observations in the field, it is believed that improved water management and agricultural methods, stream and water impoundment control, the proper use of molluscicides and mechanical barriers, and certain aspects of environmental sanitation offer practical solutions to this problem. The complexity of these measures requires the closest co-operation between the various agencies, national and international, concerned with agriculture, water resources and public health. PMID:20604119

  17. Middle East respiratory syndrome.

    PubMed

    Zumla, Alimuddin; Hui, David S; Perlman, Stanley

    2015-09-01

    Middle East respiratory syndrome (MERS) is a highly lethal respiratory disease caused by a novel single-stranded, positive-sense RNA betacoronavirus (MERS-CoV). Dromedary camels, hosts for MERS-CoV, are implicated in direct or indirect transmission to human beings, although the exact mode of transmission is unknown. The virus was first isolated from a patient who died from a severe respiratory illness in June, 2012, in Jeddah, Saudi Arabia. As of May 31, 2015, 1180 laboratory-confirmed cases (483 deaths; 40% mortality) have been reported to WHO. Both community-acquired and hospital-acquired cases have been reported with little human-to-human transmission reported in the community. Although most cases of MERS have occurred in Saudi Arabia and the United Arab Emirates, cases have been reported in Europe, the USA, and Asia in people who travelled from the Middle East or their contacts. Clinical features of MERS range from asymptomatic or mild disease to acute respiratory distress syndrome and multiorgan failure resulting in death, especially in individuals with underlying comorbidities. No specific drug treatment exists for MERS and infection prevention and control measures are crucial to prevent spread in health-care facilities. MERS-CoV continues to be an endemic, low-level public health threat. However, the virus could mutate to have increased interhuman transmissibility, increasing its pandemic potential.

  18. Middle East respiratory syndrome.

    PubMed

    Zumla, Alimuddin; Hui, David S; Perlman, Stanley

    2015-09-01

    Middle East respiratory syndrome (MERS) is a highly lethal respiratory disease caused by a novel single-stranded, positive-sense RNA betacoronavirus (MERS-CoV). Dromedary camels, hosts for MERS-CoV, are implicated in direct or indirect transmission to human beings, although the exact mode of transmission is unknown. The virus was first isolated from a patient who died from a severe respiratory illness in June, 2012, in Jeddah, Saudi Arabia. As of May 31, 2015, 1180 laboratory-confirmed cases (483 deaths; 40% mortality) have been reported to WHO. Both community-acquired and hospital-acquired cases have been reported with little human-to-human transmission reported in the community. Although most cases of MERS have occurred in Saudi Arabia and the United Arab Emirates, cases have been reported in Europe, the USA, and Asia in people who travelled from the Middle East or their contacts. Clinical features of MERS range from asymptomatic or mild disease to acute respiratory distress syndrome and multiorgan failure resulting in death, especially in individuals with underlying comorbidities. No specific drug treatment exists for MERS and infection prevention and control measures are crucial to prevent spread in health-care facilities. MERS-CoV continues to be an endemic, low-level public health threat. However, the virus could mutate to have increased interhuman transmissibility, increasing its pandemic potential. PMID:26049252

  19. Treated Wastewater's Potential for Improving Water and Food Security in the Middle East and North Africa

    NASA Astrophysics Data System (ADS)

    Dare, A. E.

    2014-12-01

    The Middle East and North Africa (MENA) contains just 1% of the world's freshwater; however, even in the very arid countries of the Gulf region, high quality treated wastewater rarely sees a productive use. As countries deal with growing populations and strive for increased food security, freshwater alone cannot be relied upon to meet these demands. This research identifies best practices from the MENA for reusing treated wastewater in agricultural production, and calculates the potential of treated wastewater for increasing food production in select countries. Drawing upon both published and original treated wastewater quality data for locations in the MENA, the annual volume of treated wastewater produced, and crop water demands, estimates for potential crop production from treated wastewater are calculated. The volume of wastewater treated annually is equivalent to 10-40% of agricultural withdrawals in most MENA countries. Irrigation by treated wastewater has significant potential to impact water and food security by reducing agricultural water withdrawals and increasing domestic food production. Such initiatives require application of best management practices, such as transparent monitoring and evaluation of reuse projects for public and environmental health risks, and support from both farmers and policy makers.

  20. Middle East Respiratory Syndrome

    PubMed Central

    Zumla, Alimuddin; Hui, David S; Perlman, Stanley

    2016-01-01

    SUMMARY The Middle East Respiratory Syndrome (MERS) is a newly recognized highly lethal respiratory disease caused by a novel single stranded, positive sense RNA betacoronavirus (MERS-CoV). Dromedary camels, host species for MERS-CoV are implicated in the direct or indirect transmission to humans, although the exact mode of transmission remains unknown. First isolated from a patient who died from a severe respiratory illness in June 2012 in Jeddah, Saudi Arabia, as of 16 February 2015, 983 laboratory-confirmed cases of MERS-CoV (360 deaths; 36.6% mortality) were reported to the WHO. Cases have been acquired in both the community and hospitals with limited human-to-human transmission reported in the community. Whilst the majority of MERS cases have occurred in Saudi Arabia and the United Arab Emirates, cases have been reported from Europe, USA and Asia in people who traveled from the Middle East or their contacts. Clinical features of MERS range from asymptomatic or mild disease to acute respiratory distress syndrome and multi-organ failure resulting in death, especially in individuals with underlying co-morbidities. There is no specific drug treatment for MERS and infection prevention and control measures are crucial to prevent spread of MERS-CoV in health care facilities. MERS-CoV continues to be an endemic,low level public health threat. However, the concern remains that the virus could mutate to exhibit increased interhuman transmissibility, increasing pandemic potential. Our seminar presents an overview of current knowledge and perspectives on the epidemiology, virology, mode of transmission, pathogen-host responses, clinical features, diagnosis and development of new drugs and vaccines. PMID:26049252

  1. Hydrologic modeling for monitoring water availability in Africa and the Middle East

    NASA Astrophysics Data System (ADS)

    McNally, A.; Getirana, A.; Arsenault, K. R.; Peters-Lidard, C. D.; Verdin, J. P.

    2015-12-01

    Drought impacts water resources required by crops and communities, in turn threatening lives and livelihoods. Early warning systems, which rely on inputs from hydro-climate models, are used to help manage risk and provide humanitarian assistance to the right place at the right time. However, translating advancements in hydro-climate science into action is a persistent and time-consuming challenge: scientists and decision-makers need to work together to enhance the salience, credibility, and legitimacy of the hydrological data products being produced. One organization that tackles this challenge is the Famine Early Warning Systems Network (FEWS NET), which has been using evidence-based approaches to address food security since the 1980s.In this presentation, we describe the FEWS NET Land Data Assimilation System (FLDAS), developed by FEWS NET and NASA hydrologic scientists to maximize the use of limited hydro-climatic observations for humanitarian applications. The FLDAS, an instance of the NASA Land Information System (LIS), is comprised of land surface models driven by satellite rainfall inputs already familiar to FEWS NET food security analysts. First, we evaluate the quality of model outputs over parts of the Middle East and Africa using remotely sensed soil moisture and vegetation indices. We then describe derived water availability indices that have been identified by analysts as potentially useful sources of information. Specifically, we demonstrate how the Baseline Water Stress and Drought Severity Index detect recent water availability crisis events in the Tigris-Euphrates Basin and the Gaborone Reservoir, Botswana. Finally we discuss ongoing work to deliver this information to FEWS NET analysts in a timely and user-friendly manner, with the ultimate goal of integrating these water availability metrics into regular decision-making activities.

  2. Regions. [Africa, Middle East].

    PubMed

    1985-03-01

    This discussion of population focuses on the regions of Africa and the Middle East. In South Africa more white women are working but fewer black women work. The overall result is that the percentage of women who work is declining. Marita de Beer, research liaison executive at the South African Advertising Research Foundation, reports that the female population grew by 31% in the past 10 years while the number of working women has grown by only 11%. Among blacks the female population rose by 36%, but the number of workers among them declined by about 1%. Married women are among the fastest growing groups of working women in South Africa. The most recent estimate of the population of Nigeria is 92 million. According to Professor Vremudia Diejomaoh, Nigeria's population will probably reach 155 million by 2000 with 33% living in urban areas. In Saudi Arabia the Pan Arab Research Center recently completed a census of retail outlets in 3 metropolitan areas: Jeddah, Riyadh, and Dammam. The types of outlets surveyed include large supermarkets, small supermarkets, groceries with and without deep freeze, tobacco shops, meat shop/delis, small cafeterias, large restaurants/hotels, cosmetics shops or perfumeries, camera stores, toy shops, pharmacies, watch and gift shop, newsstands, department store, and appliance outlets. Using the Census of Retail Outlets as a base, Pan Arab Research Center also has a new distribution audit system that will cover 500 outlets. By plotting Arab countries according to their population policies and their current growth rates, it is possible to project where the middle class will grow fastest in the Arab world. The countries that have declining growth rates and strong population programs designed to encourage lower fertility rates among women are Egypt, Tunisia, Morocco, Algeria, and Lebanon. The countries most likely to have a better per capita distribution of resources within this decade are those where governments encourage reductions in

  3. Regions. [Africa, Middle East].

    PubMed

    1985-03-01

    This discussion of population focuses on the regions of Africa and the Middle East. In South Africa more white women are working but fewer black women work. The overall result is that the percentage of women who work is declining. Marita de Beer, research liaison executive at the South African Advertising Research Foundation, reports that the female population grew by 31% in the past 10 years while the number of working women has grown by only 11%. Among blacks the female population rose by 36%, but the number of workers among them declined by about 1%. Married women are among the fastest growing groups of working women in South Africa. The most recent estimate of the population of Nigeria is 92 million. According to Professor Vremudia Diejomaoh, Nigeria's population will probably reach 155 million by 2000 with 33% living in urban areas. In Saudi Arabia the Pan Arab Research Center recently completed a census of retail outlets in 3 metropolitan areas: Jeddah, Riyadh, and Dammam. The types of outlets surveyed include large supermarkets, small supermarkets, groceries with and without deep freeze, tobacco shops, meat shop/delis, small cafeterias, large restaurants/hotels, cosmetics shops or perfumeries, camera stores, toy shops, pharmacies, watch and gift shop, newsstands, department store, and appliance outlets. Using the Census of Retail Outlets as a base, Pan Arab Research Center also has a new distribution audit system that will cover 500 outlets. By plotting Arab countries according to their population policies and their current growth rates, it is possible to project where the middle class will grow fastest in the Arab world. The countries that have declining growth rates and strong population programs designed to encourage lower fertility rates among women are Egypt, Tunisia, Morocco, Algeria, and Lebanon. The countries most likely to have a better per capita distribution of resources within this decade are those where governments encourage reductions in

  4. Understanding and predicting climate variations in the Middle East for sustainable water resource management and development

    NASA Astrophysics Data System (ADS)

    Samuels, Rana

    Water issues are a source of tension between Israelis and Palestinians. In the and region of the Middle East, water supply is not just scarce but also uncertain: It is not uncommon for annual rainfall to be as little as 60% or as much as 125% of the multiannual average. This combination of scarcity and uncertainty exacerbates the already strained economy and the already tensed political situation. The uncertainty could be alleviated if it were possible to better forecast water availability. Such forecasting is key not only for water planning and management, but also for economic policy and for political decision making. Water forecasts at multiple time scales are necessary for crop choice, aquifer operation and investments in desalination infrastructure. The unequivocal warming of the climate system adds another level of uncertainty as global and regional water cycles change. This makes the prediction of water availability an even greater challenge. Understanding the impact of climate change on precipitation can provide the information necessary for appropriate risk assessment and water planning. Unfortunately, current global circulation models (GCMs) are only able to predict long term climatic evolution at large scales but not local rainfall. The statistics of local precipitation are traditionally predicted using historical rainfall data. Obviously these data cannot anticipate changes that result from climate change. It is therefore clear that integration of the global information about climate evolution and local historical data is needed to provide the much needed predictions of regional water availability. Currently, there is no theoretical or computational framework that enables such integration for this region. In this dissertation both a conceptual framework and a computational platform for such integration are introduced. In particular, suite of models that link forecasts of climatic evolution under different CO2 emissions scenarios to observed rainfall

  5. Sustainable Electricity and Water for Europe, Middle East and North Africa

    NASA Astrophysics Data System (ADS)

    Müller-Steinhagen, H.; Trieb, F.

    2009-04-01

    Sufficient supply of energy and water are among the key requirements for a sustainable development of nations. Both depend strongly on energy carriers such as oil, gas, coal and uranium which have limited availability and a negative impact on the environment during their use. Within the framework of a series of detailed studies, conventional and renewable energy sources available for electricity production and desalination in Europe, North Africa and the Middle East (EU-MENA) have been analysed. Scenarios have been developed for a sustainable electricity supply based on increased plant and user efficiency, and an accelerated introduction of renewable energy sources. Even if all potential exclusion criteria are applied and only those technologies are considered which will become economically competitive within the next decades, a potential has been identified which exceeds the present electricity demand by orders of magnitude. Solar energy is, in this context, the by far largest resource which will most economically be exploited in centralised solar thermal power plants. In combination with heat storage, these power plants can provide bulk and peak electricity, and can be combined with thermal or reverse osmosis desalination plants. At present, solar thermal power plants with a total capacity exceeding 10 GW are in operation or under construction in Abu Dhabi, Algeria, Egypt, Iran, Israel, Italy, Morocco, Spain and the USA. Ultimately, the increasing electricity demand of EU-MENA can only be secured in conjunction with the required climate and resource protection targets, if all renewable energy sources are exploited where appropriate, and conversion and user efficiency are increased. To utilise the enormous energy resources of the Mediterranean countries, high voltage direct current power lines will have to be built, linking the most abundant and economic resources with the load centres in the North. With electricity losses below 10% over a distance of 3000 km

  6. Security in the Middle East

    SciTech Connect

    Wells, S.F. Jr.; Bruzonsky, M.A.

    1986-01-01

    The full range of U.S. security interests in the Middle East is covered in this volume of original contributions from prominent international scholars. Case studies of key countries emphasize the prospects for peaceful political, economic, and cultural change in the region. The Arab-Israeli conflict is examined with particular attention to the ''Palestine problem,'' U.S. policy and diplomacy, and the peace process. Finally, the involvement of the U.S. and the USSR and the policy options open to them are considered. Includes chapters on oil and its role in Middle-East security issues.

  7. AED in the Middle East

    ERIC Educational Resources Information Center

    Academy for Educational Development, 2004

    2004-01-01

    Founded in 1961, the Academy for Educational Development (AED) is an independent, nonprofit, charitable organization that operates development programs in the United States and throughout the world. This directory presents an overview of the varied activities undertaken by AED throughout the Middle East. Current AED Programs include: (1) Behavior…

  8. Middle East and North African Oil.

    ERIC Educational Resources Information Center

    Al-Quazzaz, Ayad

    1981-01-01

    Traces the history of oil and natural gas in the Middle East and relates the importance of the Middle East's current stores of oil to economic development. Information is presented on the relationship of major oil companies and local governments, OPEC, rate of production, and the impact of oil on the societies of the Middle East and North Africa.…

  9. Characterizing the Effects of Irrigation in the Middle East and North Africa Using Remotely Sensed Vegetation and Water Cycle Observations

    NASA Technical Reports Server (NTRS)

    Bolten, John; Ozdogan, Mutlu; Beaudoing, Hiroko; Rodell, Matthew

    2012-01-01

    A majority of the countries in the Middle East and North Africa (MENA) region suffer from water scarcity due in part to widespread rainfall deficits, unprecedented levels of water demand, and the inefficient use of renewable freshwater resources. Since a majority of the water withdrawal in the MENA is used for irrigation, there is a desperate need for improved understanding of irrigation practices and agricultural water use in the region. Here, satellite-derived irrigation maps and crop-type agricultural data are applied to the Land Data Assimilation System for the MENA region (MENA LDAS), designed to provide regional, gridded fields of hydrological states and fluxes relevant for water resources assessments. Within MENA-LDAS, the Catchment Land Surface Model (CLSM) simulates the location, timing, and amount of water applied through agricultural irrigation practices over the region from 2002-2012. In addition to simulating the irrigation impact on evapotranspiration, soil moisture, and runoff, we also investigate regional changes in terrestrial water storage (TWS) observed from the Gravity Recovery and Climate Experiment (GRACE) and simulated by CLSM.

  10. The Middle East population puzzle.

    PubMed

    Omran, A R; Roudi, F

    1993-07-01

    An overview is provided of Middle Eastern countries on the following topics; population change, epidemiological transition theory and 4 patterns of transition in the middle East, transition in causes of death, infant mortality declines, war mortality, fertility, family planning, age and sex composition, ethnicity, educational status, urbanization, labor force, international labor migration, refugees, Jewish immigration, families, marriage patterns, and future growth. The Middle East is geographically defined as Bahrain, Egypt, Iraq, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, United Arab Emirates, Yemen, Gaza and the West Bank, Iran, Turkey, and Israel. The Middle East's population grew very little until 1990 when the population was 43 million. Population was about doubled in the mid-1950s at 80 million. Rapid growth occurred after 1950 with declines in mortality due to widespread disease control and sanitation efforts. Countries are grouped in the following ways: persistent high fertility and declining mortality with low to medium socioeconomic conditions (Jordan, Oman, Syria, Yemen, and the West Bank and Gaza), declining fertility and mortality in intermediate socioeconomic development (Egypt, Lebanon, Turkey, and Iran), high fertility and declining mortality in high socioeconomic conditions (Bahrain, Iraq, Kuwait, Qatar, Saudi Arabia, and the United Arab Emirates), and low fertility and mortality in average socioeconomic conditions (Israel). As birth and death rates decline, there is an accompanying shift from communicable diseases to degenerative diseases and increases in life expectancy; this pattern is reflected in the available data from Egypt, Kuwait, and Israel. High infant and child mortality tends to remain a problem throughout the Middle East, with the exception of Israel and the Gulf States. War casualties are undetermined, yet have not impeded the fastest growing population growth rate in the world. The average fertility is 5 births

  11. The Middle East population puzzle.

    PubMed

    Omran, A R; Roudi, F

    1993-07-01

    An overview is provided of Middle Eastern countries on the following topics; population change, epidemiological transition theory and 4 patterns of transition in the middle East, transition in causes of death, infant mortality declines, war mortality, fertility, family planning, age and sex composition, ethnicity, educational status, urbanization, labor force, international labor migration, refugees, Jewish immigration, families, marriage patterns, and future growth. The Middle East is geographically defined as Bahrain, Egypt, Iraq, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, United Arab Emirates, Yemen, Gaza and the West Bank, Iran, Turkey, and Israel. The Middle East's population grew very little until 1990 when the population was 43 million. Population was about doubled in the mid-1950s at 80 million. Rapid growth occurred after 1950 with declines in mortality due to widespread disease control and sanitation efforts. Countries are grouped in the following ways: persistent high fertility and declining mortality with low to medium socioeconomic conditions (Jordan, Oman, Syria, Yemen, and the West Bank and Gaza), declining fertility and mortality in intermediate socioeconomic development (Egypt, Lebanon, Turkey, and Iran), high fertility and declining mortality in high socioeconomic conditions (Bahrain, Iraq, Kuwait, Qatar, Saudi Arabia, and the United Arab Emirates), and low fertility and mortality in average socioeconomic conditions (Israel). As birth and death rates decline, there is an accompanying shift from communicable diseases to degenerative diseases and increases in life expectancy; this pattern is reflected in the available data from Egypt, Kuwait, and Israel. High infant and child mortality tends to remain a problem throughout the Middle East, with the exception of Israel and the Gulf States. War casualties are undetermined, yet have not impeded the fastest growing population growth rate in the world. The average fertility is 5 births

  12. Quality of water in mines in the Western Middle Coal Field, Anthracite Region, east-central Pennsylvania

    USGS Publications Warehouse

    Reed, L.A.; Beard, M.M.; Growitz, D.J.

    1987-01-01

    The quality of mine water in the 75 sq-mi Western Middle anthracite field, Pennsylvania was determined by sampling discharges and boreholes at 60 abandoned and flooded mines during 1975-78. The Vulcan-Buck Mountain mine, east-northeast of Mahanoy City, contains an estimated 6,100 acre-ft of water with a specific conductance of 380 to 460 micromhos and a pH of 4.4 to 4.6 units. Twenty-two mines are in a 15-sq mi area between Mahanoy City and Girardville, all of which closed prior to 1958. Seven of these mines in the Mahanoy Basin may contain 30,000 acre-ft of water. Specific conductance ranges from 630 micromhos in the Tunnel mine to 1,800 micromhos in the Gilberton mine. Fifteen of these mines are in the Shenandoah complex; specific conductance ranges from 240 to 310 micromhos in mines in the eastern end of the complex to 2,400 micromhos in the western end. The specific conductance of water in 25 mines in the Mount Carmel-Shamokin area ranges from 460 to 980 micromhos. The North Franklin mine near Trevorton contains about 4,900 acre-ft of water with a specific conductance of about 1,100 micromhos. (USGS)

  13. Middle East respiratory syndrome (MERS)

    PubMed Central

    Cunha, Cheston B; Opal, Steven M

    2014-01-01

    Coronaviruses have traditionally been associated with mild upper respiratory tract infections throughout the world. In the fall of 2002, a new coronavirus emerged in in Asia causing severe viral pneumonia, i.e., severe acute respiratory syndrome (SARS). Nearly a decade following the SARS epidemic, a new coronavirus causing severe viral pneumonia has emerged, i.e., middle east respiratory syndrome (MERS). Since the initial case of MERS-CoV occurred in June of 2012 in Saudi Arabia there have been 688 confirmed cases and 282 deaths in 20 countries.   Although both SARS and MERS are caused by coronaviruses, SARS was characterized by efficient human transmission and relatively low mortality rate. In contrast, MERS is relatively inefficiently transmitted to humans but has a high mortality rate. Given the potential overlap in presentation and manifestation, it is important to understand the clinical and epidemiologic differences between MERS, SARS and influenza. PMID:25089913

  14. Teaching the Literature of Today's Middle East

    ERIC Educational Resources Information Center

    Webb, Allen

    2011-01-01

    Providing a gateway into the real literature emerging from the Middle East, this book shows teachers how to make the topic authentic, powerful, and relevant. "Teaching the Literature of Today's Middle East": (1) Introduces teachers to this literature and how to teach it; (2) Brings to the reader a tremendous diversity of teachable texts and…

  15. Children in the Muslim Middle East.

    ERIC Educational Resources Information Center

    Fernea, Elizabeth Warnock, Ed.

    The Middle East has been undergoing vast social and economic change, but in all reports available today, little attention has been paid to the situation of children. The purpose of this book is to help readers better understand the children of the Middle East to give a sense of their lives today and a sense of attitudes toward children and their…

  16. Greening of the Sahara - a paleo perspective on the history of water in the Middle East and North Africa

    NASA Astrophysics Data System (ADS)

    Bar-Matthews, M.

    2012-04-01

    The Middle-East, mostly at its southern edge together with North Africa, the northern edge of the Sahara Desert, are located at the boundary between high- to-mid latitude and tropical-subtropical climate systems. The geographical duality of desert adjacent to Mediterranean-type climate regions played and still plays a major role on the water availability. Thanks to the number of important paleoclimate studies that been made on accurate dating of cave speleothems in Southern Arabia and Oman (Fleitmann et al., 2011) and in the northeast Sahara, the Negev Desert Israel (Vaks et al., 2010) and the study of sapropels in Eastern and central Mediterranean (Almogi-Labin et al., 2009; Osborne et al, 2008), it is clear that the region was graced with water during peak interglacials when the African monsoon and westerly storm/rainfall systems intensified. Northward penetration of the Inter Tropical Convergence Zone over the Arabian and African continents resulted in increased discharge of the Nile River and rivers that emerged from central Sahara into the Eastern Mediterranean Sea. Correspondingly, enhanced westerly wind activity led to an increase in rainfall from Atlantic-Mediterranean sources over the entire Mediterranean basin, which even penetrated south into the north-east corner of the Sahara Desert. The Saharo-Arabian Desert became narrower and climatic "windows" opened for the dispersal of hominids and animals out of the African continent at 250-239, 210-193, 138-120, 108-98, 87-84 and 10-6.5 ka BP, with severe dry conditions in between. Greening of the Sahara Desert at these intervals is supported also by various marine and terrestrial records, such as corals, lakes, tufa deposits and archeological findings. Dry conditions prevailed in the Sahara desert during glacials. This is in contrast to the climatic conditions in the Eastern Mediterranean coastal region and the Jordan Rift Valley (Bar-Matthews et al., 2003; Lisker et al., 2010), where water was available for

  17. Middle East food safety perspectives.

    PubMed

    Idriss, Atef W; El-Habbab, Mohammad S

    2014-08-01

    Food safety and quality assurance are increasingly a major issue with the globalisation of agricultural trade, on the one hand, and intensification of agriculture, on the other. Consumer protection has become a priority in policy-making amongst the large economies of the Middle East and North Africa (MENA) countries following a number of food safety incidents. To enhance food safety, it is necessary to establish markets underpinned by knowledge and resources, including analysis of international rejections of food products from MENA countries, international laboratory accreditation, improved reporting systems and traceability, continued development and validation of analytical methods, and more work on correlating sensory evaluation with analytical results. MENA countries should develop a national strategy for food safety based on a holistic approach that extends from farm-to-fork and involves all the relevant stakeholders. Accordingly, food safety should be a regional programme, raising awareness among policy- and decision-makers of the importance of food safety and quality for consumer protection, food trade and economic development. PMID:24415527

  18. Middle East food safety perspectives.

    PubMed

    Idriss, Atef W; El-Habbab, Mohammad S

    2014-08-01

    Food safety and quality assurance are increasingly a major issue with the globalisation of agricultural trade, on the one hand, and intensification of agriculture, on the other. Consumer protection has become a priority in policy-making amongst the large economies of the Middle East and North Africa (MENA) countries following a number of food safety incidents. To enhance food safety, it is necessary to establish markets underpinned by knowledge and resources, including analysis of international rejections of food products from MENA countries, international laboratory accreditation, improved reporting systems and traceability, continued development and validation of analytical methods, and more work on correlating sensory evaluation with analytical results. MENA countries should develop a national strategy for food safety based on a holistic approach that extends from farm-to-fork and involves all the relevant stakeholders. Accordingly, food safety should be a regional programme, raising awareness among policy- and decision-makers of the importance of food safety and quality for consumer protection, food trade and economic development.

  19. Middle East Respiratory Syndrome (MERS).

    PubMed

    Rasmussen, Sonja A; Watson, Amelia K; Swerdlow, David L

    2016-06-01

    Since the identification of the first patients with Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, over 1,600 cases have been reported as of February 2016. Most cases have occurred in Saudi Arabia or in other countries on or near the Arabian Peninsula, but travel-associated cases have also been seen in countries outside the Arabian Peninsula. MERS-CoV causes a severe respiratory illness in many patients, with a case fatality rate as high as 40%, although when contacts are investigated, a significant proportion of patients are asymptomatic or only have mild symptoms. At this time, no vaccines or treatments are available. Epidemiological and other data suggest that the source of most primary cases is exposure to camels. Person-to-person transmission occurs in household and health care settings, although sustained and efficient person-to-person transmission has not been observed. Strict adherence to infection control recommendations has been associated with control of previous outbreaks. Vigilance is needed because genomic changes in MERS-CoV could result in increased transmissibility, similar to what was seen in severe acute respiratory syndrome coronavirus (SARS-CoV). PMID:27337460

  20. Groundwater depletion in the Middle East from GRACE with implications for transboundary water management in the Tigris-Euphrates-Western Iran region

    PubMed Central

    Voss, Katalyn A; Famiglietti, James S; Lo, MinHui; Linage, Caroline; Rodell, Matthew; Swenson, Sean C

    2013-01-01

    In this study, we use observations from the Gravity Recovery and Climate Experiment (GRACE) satellite mission to evaluate freshwater storage trends in the north-central Middle East, including portions of the Tigris and Euphrates River Basins and western Iran, from January 2003 to December 2009. GRACE data show an alarming rate of decrease in total water storage of approximately −27.2±0.6 mm yr−1 equivalent water height, equal to a volume of 143.6 km3 during the course of the study period. Additional remote-sensing information and output from land surface models were used to identify that groundwater losses are the major source of this trend. The approach used in this study provides an example of “best current capabilities” in regions like the Middle East, where data access can be severely limited. Results indicate that the region lost 17.3±2.1 mm yr−1 equivalent water height of groundwater during the study period, or 91.3±10.9 km3 in volume. Furthermore, results raise important issues regarding water use in transboundary river basins and aquifers, including the necessity of international water use treaties and resolving discrepancies in international water law, while amplifying the need for increased monitoring for core components of the water budget. PMID:23658469

  1. Groundwater depletion in the Middle East from GRACE with implications for transboundary water management in the Tigris-Euphrates-Western Iran region.

    PubMed

    Voss, Katalyn A; Famiglietti, James S; Lo, Minhui; Linage, Caroline; Rodell, Matthew; Swenson, Sean C

    2013-02-01

    In this study, we use observations from the Gravity Recovery and Climate Experiment (GRACE) satellite mission to evaluate freshwater storage trends in the north-central Middle East, including portions of the Tigris and Euphrates River Basins and western Iran, from January 2003 to December 2009. GRACE data show an alarming rate of decrease in total water storage of approximately -27.2±0.6 mm yr(-1) equivalent water height, equal to a volume of 143.6 km(3) during the course of the study period. Additional remote-sensing information and output from land surface models were used to identify that groundwater losses are the major source of this trend. The approach used in this study provides an example of "best current capabilities" in regions like the Middle East, where data access can be severely limited. Results indicate that the region lost 17.3±2.1 mm yr(-1) equivalent water height of groundwater during the study period, or 91.3±10.9 km(3) in volume. Furthermore, results raise important issues regarding water use in transboundary river basins and aquifers, including the necessity of international water use treaties and resolving discrepancies in international water law, while amplifying the need for increased monitoring for core components of the water budget.

  2. Groundwater Depletion in the Middle East from GRACE with Implications for Transboundary Water Management in the Tigris-Euphrates-Western Iran Region

    NASA Technical Reports Server (NTRS)

    Voss, Katalyn; Famiglietti, James S.; Lo, MinHui; de Linage, Caroline; Rodell, Matthew; Swenson, Sean C.

    2013-01-01

    In this study, we use observations from the Gravity Recovery and Climate Experiment (GRACE) satellite mission to evaluate freshwater storage trends in the north-central Middle East, including portions of the Tigris and Euphrates River Basins and western Iran, from January 2003 to December 2009. GRACE data show an alarming rate of decrease in total water storage of approximately -27.2 plus or minus 0.6 mm per yr equivalent water height, equal to a volume of 143.6 cubic kilometers during the course of the study period. Additional remote-sensing information and output from land surface models were used to identify that groundwater losses are the major source of this trend. The approach used in this study provides an example of ''best current capabilities'' in regions like the Middle East, where data access can be severely limited. Results indicate that the region lost 17.3 plus or minus 2.1 mm per yr equivalent water height of groundwater during the study period, or 91.3 plus or minus 10.9 cubic kilometers in volume. Furthermore, results raise important issues regarding water use in transboundary river basins and aquifers, including the necessity of international water use treaties and resolving discrepancies in international water law, while amplifying the need for increased monitoring for core components of the water budget

  3. Groundwater Depletion in the Middle East from GRACE with Implications for Transboundary Water Management in the Tigris-Euphrates-Western Iran Region

    NASA Technical Reports Server (NTRS)

    Voss, Katalyn A.; Famiglietti, James S.; Lo, MinHui; De Linage, Caroline; Rodell, Matthew; Swenson, Sean C.

    2013-01-01

    In this study, we use observations from the Gravity Recovery and Climate Experiment (GRACE) satellite mission to evaluate freshwater storage trends in the north-central Middle East, including portions of the Tigris and Euphrates River Basins and western Iran, from January 2003 to December 2009. GRACE data show an alarming rate of decrease in total water storage of approximately -27.2 plus or minus 0.6 millimeters per year equivalent water height, equal to a volume of 143.6 cubic kimometers during the course of the study period. Additional remote-sensing information and output from land surface models were used to identify that groundwater losses are the major source of this trend. The approach used in this study provides an example of ''best current capabilities'' in regions like the Middle East, where data access can be severely limited. Results indicate that the region lost 17.3 plus or minus 2.1 millimeters per year equivalent water height of groundwater during the study period, or 91.3 plus or minus 10.9 cubic kilometers in volume. Furthermore, results raise important issues regarding water use in transboundary river basins and aquifers, including the necessity of international water use treaties and resolving discrepancies in international water law, while amplifying the need for increased monitoring for core components of the water budget.

  4. MISR Views the Middle East

    NASA Technical Reports Server (NTRS)

    2000-01-01

    This image, generated using 16 orbits of MISR data collected between August 16 and August 30, 2000, takes us to the cradle of many civilizations. The data are from the 60-degree aftward-viewing camera. Because the individual orbit swaths are only 400 kilometers wide, they were 'mosaiced' together to form this composite picture, which covers about 2700 kilometers from west to east and 1750 kilometers from north to south. A few discontinuities are present in the mosaic, particularly near clouds, due to changes in the scene which occurred between dates when the individual orbit data were acquired.

    At the northern tip of the Red Sea, the Gulf of Suez and the Gulf of Aqaba frame the sandy deserts and spectacular mountains of the Sinai Peninsula. The highest peaks are Gebel Katherina (Mountain of St. Catherine, 2637 meters) and Gebel Musa (Mountain of Moses, also known as Mount Sinai, 2285 meters). To the northeast, Israel and Jordan flank the Dead Sea, one of the saltiest inland water bodies in the world. At its northern edge is Qumran, where the ancient Scrolls were discovered; the city of Jerusalem lies about 30 kilometers to the west.

    Several large rivers are prominent. Flowing southeastward through Iraq are the Tigris and Euphrates. The dark area between the two rivers, northwest of the Persian Gulf, is a very fertile region where fishing and farming are prevalent. Wending its way through eastern Egypt is the Nile. In the south is Lake Nasser and the Aswan Dam; continuing northward the Nile passes the Temple of Luxor as it sharply loops to the east. It then turns west and northward, eventually passing the capital city of Cairo, and finally spreading into a prominent delta as it empties into the Mediterranean Sea. The bright dot just west of the apex of the delta marks the location of the great Pyramids and Sphinx complexes on the Giza Plateau. On the coast, west of the delta, is the ancient city of Alexandria, Egypt's main seaport.

    'MISR', as it turns

  5. Estimation of Severe Middle East Respiratory Syndrome Cases in the Middle East, 2012-2016.

    PubMed

    O'Hagan, Justin J; Carias, Cristina; Rudd, Jessica M; Pham, Huong T; Haber, Yonat; Pesik, Nicki; Cetron, Martin S; Gambhir, Manoj; Gerber, Susan I; Swerdlow, David L

    2016-10-01

    Using data from travelers to 4 countries in the Middle East, we estimated 3,250 (95% CI 1,300-6,600) severe cases of Middle East respiratory syndrome occurred in this region during September 2012-January 2016. This number is 2.3-fold higher than the number of laboratory-confirmed cases recorded in these countries. PMID:27648640

  6. Armageddon, oil, and the Middle East crisis

    SciTech Connect

    Walvoord, J.F.; Walvoord, J.E.

    1980-01-01

    This book relates the intricate subject of biblical prophecy to the current crisis in the Middle East. With the development of oil politics, Dr. Walvoord believes a new world government will emerge, centered in the Middle East, which will eclipse the United States and Russia as world powers. The world government will be subjected to catastrophic, divine judgments which precipitate a gigantic world war culminating in Armageddon. Each chapter is devoted to the scriptural explanations of events leading to the second coming of Christ. The result is a prophetic calendar summing up to the countdown to Armageddon. Some of the chapter titles include: the Arab oil blackmail; watch Jerusalen; the rising tide of world religion; the coming Middle East peace; the coming world dictator; and Armageddon: the world's death struggle.

  7. Education Quality in the Middle East

    NASA Astrophysics Data System (ADS)

    Chapman, David W.; Miric, Suzanne L.

    2009-07-01

    Some of the most dramatic growth in the provision of primary and secondary education over the last decade has occurred across countries of the Middle East and North Africa (MENA). Yet student achievement across MENA is lagging compared to many other parts of the world. Low quality of education is a primary concern and one of the greatest challenges facing education and government leaders across the region. This paper summarises recent evidence regarding student learning in the MENA region and draws on Galal's model of policy formulation in considering ways that governments across the Middle East might address this problem.

  8. The Middle East in global strategy

    SciTech Connect

    Braun, A.

    1986-01-01

    This book emphasizes the links between international politics and strategy. The contributors provide an analysis of the strategic interests of the major international actors in the Middle East. The policies of the superpowers toward the Middle East are evaluated. The awareness of the strategic value and interests of two key regional actors - Syria and Israel - are discussed. The author further discusses NATO and the Warsaw Treaty Organization (WTO), West European allies and the U.S., as well as Soviet dominance in foreign policy decisions made in the WTO. There is emphasis on the Arab-Israeli conflict and the Iran-Iraq war.

  9. Media and Teaching about the Middle East

    ERIC Educational Resources Information Center

    Kaviani, Khodadad

    2009-01-01

    This qualitative study was conducted in 2006-2007 and found that teachers relied on a variety of readily available media to stay informed about the Middle East and used some of them in their teaching. Teachers tried to explain to their students that every Middle Eastern Muslim is not a terrorist and Iraq was not behind the 9/11 terrorist attacks.…

  10. Education Quality in the Middle East

    ERIC Educational Resources Information Center

    Chapman, David W.; Miric, Suzanne L.

    2009-01-01

    Some of the most dramatic growth in the provision of primary and secondary education over the last decade has occurred across countries of the Middle East and North Africa (MENA). Yet student achievement across MENA is lagging compared to many other parts of the world. Low quality of education is a primary concern and one of the greatest…

  11. Academic Freedom and Middle East Studies

    ERIC Educational Resources Information Center

    Colla, Elliott

    2007-01-01

    When the author and his colleague Marsha Pripstein Posusney of Bryant College organized a workshop, entitled "The Study of the Middle East and Islam: Challenges after 9-11," at the Watson Institute for International Studies at Brown University, he naively assumed it would come off without friction. After all, he thought, they were not even talking…

  12. Estimation of Severe Middle East Respiratory Syndrome Cases in the Middle East, 2012–2016

    PubMed Central

    Carias, Cristina; Rudd, Jessica M.; Pham, Huong T.; Haber, Yonat; Pesik, Nicki; Cetron, Martin S.; Gambhir, Manoj; Gerber, Susan I.; Swerdlow, David L.

    2016-01-01

    Using data from travelers to 4 countries in the Middle East, we estimated 3,250 (95% CI 1,300–6,600) severe cases of Middle East respiratory syndrome occurred in this region during September 2012–January 2016. This number is 2.3-fold higher than the number of laboratory-confirmed cases recorded in these countries. PMID:27648640

  13. RAND's Impact in the Middle East. Corporate Publication

    ERIC Educational Resources Information Center

    RAND Corporation, 2015

    2015-01-01

    The RAND Corporation works throughout the Middle East to analyze complex policy problems and help policymakers create enduring solutions. RAND's work in the Middle East focuses on the issues that drive economic development. This brief report provides an overview of RAND's impact in the Middle East in the areas of supporting youth, health and…

  14. The post-war Middle East

    SciTech Connect

    Tempest, P.

    1992-03-09

    The Middle East remains today the global energy fulcrum. One year after the Persian Gulf war, the region is in greater turmoil and political uncertainty than it has known in modern times. The Iraqi invasion of Kuwait and subsequent external military intervention forced neighboring states to question the need for a foreign military presence in the future. The rift between the secular revolutionary states in the region led by Iraq, Libya, Yemen, Algeria, and Syria and the traditional monarchy of Saudi Arabia and the emirates of the gulf has widened. Egypt provides, at present, an uncomfortable bridge. The balance of political forces may be shifting. This paper attempts to answer the following questions: Where will we see the new leadership in the Middle East Will it again play a role through the Organization of Petroleum Exporting Countries and determination of the oil price in shaping the structure of global energy supply and demand

  15. Understanding farmers' intention and behavior regarding water conservation in the Middle-East and North Africa: a case study in Iran.

    PubMed

    Yazdanpanah, Masoud; Hayati, Dariush; Hochrainer-Stigler, Stefan; Zamani, Gholam Hosein

    2014-03-15

    There is a high risk of serious water shortages in Middle-East and North African countries. To decrease this threat water conservation strategies are gaining overall importance and one main focus is now on farmer's behavior. Among other dimensions it is assumed that normative issues play an important role in predicting environmental oriented intentions and actual actions. To empirically test the possible interactions the Theory of Planned Behavior was used, revised and expanded for the specific case on water management issues and applied to Iranian farmers. The results could not validate the TPB framework which emphasizes the importance of perceived behavioral control for intention and actual behavior and findings are much more in line with the Theory of Reasoned Action. Normative inclinations as well as perception of risk are found to be important for intention as well as actual water conservation behavior. Additionally, the importance and linkages of the dimensions are found to be different between sub-groups of farmers, especially between traditional water management farmers and those who already using advanced water management strategies. This raises the question if one-fits-all behavioral models are adequate for practical studies where sub-groups may very much differ in their actions. Still, our study suggests that in the context of water conservation, normative inclination is a key dimension and it may be useful to consider the role of positive, self-rewarding feelings for farmers when setting up policy measures in the region.

  16. Understanding farmers' intention and behavior regarding water conservation in the Middle-East and North Africa: a case study in Iran.

    PubMed

    Yazdanpanah, Masoud; Hayati, Dariush; Hochrainer-Stigler, Stefan; Zamani, Gholam Hosein

    2014-03-15

    There is a high risk of serious water shortages in Middle-East and North African countries. To decrease this threat water conservation strategies are gaining overall importance and one main focus is now on farmer's behavior. Among other dimensions it is assumed that normative issues play an important role in predicting environmental oriented intentions and actual actions. To empirically test the possible interactions the Theory of Planned Behavior was used, revised and expanded for the specific case on water management issues and applied to Iranian farmers. The results could not validate the TPB framework which emphasizes the importance of perceived behavioral control for intention and actual behavior and findings are much more in line with the Theory of Reasoned Action. Normative inclinations as well as perception of risk are found to be important for intention as well as actual water conservation behavior. Additionally, the importance and linkages of the dimensions are found to be different between sub-groups of farmers, especially between traditional water management farmers and those who already using advanced water management strategies. This raises the question if one-fits-all behavioral models are adequate for practical studies where sub-groups may very much differ in their actions. Still, our study suggests that in the context of water conservation, normative inclination is a key dimension and it may be useful to consider the role of positive, self-rewarding feelings for farmers when setting up policy measures in the region. PMID:24513405

  17. Recent developments of the Middle East catalog

    NASA Astrophysics Data System (ADS)

    Zare, Mehdi; Amini, Hamideh; Yazdi, Pouye; Sesetyan, Karin; Demircioglu, Mine Betul; Kalafat, Dogan; Erdik, Mustafa; Giardini, Domenico; Khan, M. Asif; Tsereteli, Nino

    2014-10-01

    This article summarizes a recent study in the framework of the Global Earth model (GEM) and the Earthquake Model of the Middle East (EMME) project to establish the new catalog of seismicity for the Middle East, using all historical (pre-1900), early and modern instrumental events up to 2006. According to different seismicity, which depends on geophysical, geological, tectonic, and seismicity data, this region is subdivided to nine subregions, consisting of Alborz-Azerbaijan, Afghanistan-Pakistan, Saudi Arabia, Caucasus, Central Iran, Kopeh-Dagh, Makran, Zagros, and Turkey (Eastern Anatolia; after 30° E). After omitting the duplicate events, aftershocks, and foreshocks by using the Gruenthal method, and uniform all magnitude to Mw scale, 28,244 main events remain for the new catalog of Middle East from 1250 B.C. through 2006. The magnitude of completeness ( Mc) was determined as 4.9 for five out of nine subregions, where the least values of Mc were found to be 4.2. The threshold of Mc is around 5.5, 5.0, 4.5, and 4.0, for the time after 1950, 1963, 1975, and 2000, respectively. The average of teleseismic depths in all regions is less than 15 km. Totally, majority of depth for Kopeh-Dagh and Central Iran, Zagros, and Alborz-Azerbaijan, approximately, is 15, 13, and 11 km and for Afghanistan-Pakistan, Caucasus, Makran, Turkey (after 30° E), and Saudi Arabia is about 9 km.

  18. Huntington Disease (Chorea) in the Middle East

    PubMed Central

    Scrimgeour, Euan M

    2009-01-01

    Huntington disease (HD) has been reported in Arab families in several Middle East countries including Saudi Arabia, Oman, Syria, Lebanon, and Egypt and in non-Arab populations in other countries in the region. It is probably under-reported, and until now, has not been recorded in Yemen, the United Arab Emirates, Jordan or in Iraq. The Middle East has always been on the crossroads of trade and travel, and HD was probably introduced to some of these countries in previous times. The prevalence rate in Middle Eastern Arabs is estimated to vary from 3 to 4 per 100,000. Although the HD gene which codes for the protein huntingtin has been identified, the function of this protein is not known. At present, no treatment has been found to delay the onset of HD or to treat it effectively. Although relatively rare, HD has increasingly become a focus of international gene research, with the support and collaboration of the International Huntington Association (IHA). The IHA has been represented in Saudi Arabia and Oman. PMID:21509270

  19. In search of an oasis: Opportunity in the Middle East

    SciTech Connect

    VanderMeer, D.C.

    1996-03-01

    Across the Middle East, people contend with heat, dust, lack of rainfall, and a harsh geography. In this century, industrial development, political upheaval, and war have left a legacy of environmental and health problems. Scarce arable land is being lost to desertification. Fresh water is diverted, misused, and polluted with hazardous wastes, sewage, and agricultural and other chemicals. Coastal zones are polluted with oil, threatening pristine coral reefs, wild fowl, and fishing areas. Unprecedented urbanization and migration of traditionally rural peoples and resettlement of political refugees and foreign workers strain city services. Yet there is reason for optimism in the Middle East. Peace in the region is in sight, bringing an opportunity to stop the rapid environmental decline. Technology is available to assess the degradation, and the impact of environmental conditions on human health can be quantified.

  20. MERI reports on the Middle East

    SciTech Connect

    Not Available

    1985-01-01

    The MERI Reports on the current political and economic situation of the major countries of the Middle East have established themselves as one of the most authoritative sources for the region. The volumes have been expanded by the addition of considerable statistical appendices for each country. This book presents MERI Reports on Middle East Countries. Each report has five general sections; 1. Summary Conclusions. 2. Background Description. 3. Political Analysis. 4. Economic Analysis. 5. Statistical and Tabular Data. The Political Analysis is broken down into an overview of recent internal and external developments, an analysis of the present situation (internal and external), country-specific or regional issues, and projections. The Economic Analysis is divided into macroeconomic analysis, planning, sectoral analyses, balance-of-payments, opportunities for foreign business, and projections. The section on Data begins with basic information and then gives specialized data on politics, defence, resources (natural and human), the economy, transport, communications, and health, education and welfare. The statistics and tables on the economy deal successively with basic indicators, banking and finance, energy, industry, agriculture and fishing, development, trade, and labor.

  1. Global perspectives--the Middle East: Egypt.

    PubMed

    Aidaros, H

    2005-08-01

    The Middle East region is characterised by the grouping of 20 countries with similar cultural traditions and religious concepts. The majority of the population of this region follows the religion of Islam, which considers all animals as important as humans, and others follow Christianity and Judaism. The majority of people dealing with animals have their own religious concepts, but most countries have no clear enforced official animal welfare regulations. Animal welfare activities in the Middle East region, as in Egypt for example, are carried out by various individuals, non-governmental organisations and the official Veterinary Services. The slaughter of animals for human consumption is in accordance with Islamic rites, which is the least painful method for the animals. Extensive production systems are the predominant systems in the region, and it is not common for animals in the region to suffer stress during production processes or slaughter. Although some success has been achieved in the area of animal welfare, as seen in improvements in health care, the development of modern abattoirs with proper facilities, and the establishment of policies for combating stray dogs, there are still major constraints to the implementation of effective animal welfare measures, including those for wildlife. These constraints include the lack of finances and the absence of effective legislative measures to prevent the trapping and/or hunting of wild animals for pleasure or illegal trade.

  2. Purdah and overpopulation in the Middle East.

    PubMed

    Misch, A

    1990-01-01

    The Middle East and North Africa constitute the Islamic world. From Morocco to Afghanistan the population is 340 million and growing at a rate of 3% annually and will double in 23 years. Currently food, water, and land resources are being taxed to their limit and continued growth will only cause larger scale problems for the region. To complicate the issue public policies and private practices and attitudes are leading to continued population growth. The rise of Islamic fundamentalism does not recognize the problem of over population. In fact the revision of family law by fundamentalist politicians has done a great deal of damage to the improvements in the status of women throughout the region. The revival of Purdah, the practice of keeping women out of the public eye and confined to home, is just one example or how the rise of Islamic fundamentalism is turning back the clock in terms of women's rights. The primary disadvantage is that since women are being returned to the home, their only source of values is as child bearers. Women cloistered at home are expected to be prolific child bearers, in fact their value as human beings is judged primarily on this basis. It is their ability to bear sons that is coveted. This of course will only compound the population problems being experienced in the region. Few countries have tried to institute state wide family planning programs, namely: Algeria, Egypt, Morocco, Tunisia and Yemen, but none of these programs has been very successful. In Iraq, Kuwait, Oman and Saudi Arabia, population growth is viewed as a positive event because it will help eliminate the need for foreign workers. Even in this region, educated people have a lower fertility rate. For example in Jordan 60% of illiterate males "did not believe in" contraception while only 15% of men educated past the secondary level felt the same way. If women are forced out of the labor force and into the home to have children, the population problem will only grow.

  3. Sn Attenuation in the Middle-East

    NASA Astrophysics Data System (ADS)

    Ku, W.; Kaviani, A.; Bao, X.; Sandvol, E. A.

    2015-12-01

    The Turkish-Iranian Plateau and Zagros Mountains, a dominant tectonic feature in the Middle-East, were formed as a result of the continental collision (between Arabian plate and Eurasia plates). In order to better understand the nature of the lithosphere mantle and origin of the measure seismic velocity anomalies we have made detailed measurements of the uppermost mantle attenuation using the high frequency regional phase Sn. In order to measure Sn attenuation. We have collected a large data set consisting of 18 years (1995-2012) of waveforms recorded by 305 permanent and temporary stations. We used a bandpass filter (0.1-0.5Hz) to identify efficient longer period Sn phases. In order to determine Sn Q we applied a Two Station Method (TSM) and Reverse Two Station Method (RTM) to eliminate the source effects. We have used the LSQR algorithm to tomographically map Sn attenuation tomography across the Middle-East. We also determined the Sn propagation efficiencies visually and tomographically map qualitatively assigned Sn propagation efficiencies across the Middle-East. The Sn Attenuation Tomography show moderately low Q values beneath the Turkish-Iranian Plateau (~250) and high Q values beneath the south Caspian sea (~400) and Arabian shield (~400). We also observe high Q values beneath the Zagros mountains (~450) that is consistent with the Arabian plate underthrusting beneath the Eurasia plate. The Sn Efficiency Tomography shows high attenuation within the Turkish-Iranian Plateau and low attenuation in the Arabian Plate and across the Caspian Sea. This is consistent with prior studies that suggest a hot and thin lithosphere beneath the Turkish-Iranian Plateau and it also suggests that intrinsic attenuation is the dominant component in Sn Q across the Turkish-Iranian Plateau. Due to the signal-to-noise criterion to select amplitudes and the efficiency criterion to select two-station and reverse-two-station paths for the inversion, the data are left-censored and the

  4. Middle East Respiratory Syndrome Virus Pathogenesis.

    PubMed

    Singh, Sunit K

    2016-08-01

    Coronaviruses (CoVs) are enveloped RNA viruses that infect birds, mammals, and humans. Infections caused by human coronaviruses (hCoVs) are mostly associated with the respiratory, enteric, and nervous systems. The hCoVs only occasionally induce lower respiratory tract disease, including bronchitis, bronchiolitis, and pneumonia. In 2002 to 2003, a global outbreak of severe acute respiratory syndrome (SARS) was the seminal detection of a novel CoV (SARS-CoV). A decade later (June 2012), another novel CoV was implicated as the cause of Middle East respiratory syndrome (MERS) in Saudi Arabia. Although bats might serve as a reservoir of MERS-CoV, it is unlikely that they are the direct source for most human cases. Severe lines of evidence suggest that dromedary camels have been the major cause of transmission to humans. The emergence of MERS-CoV has triggered serious concerns about the potential for a widespread outbreak. All MERS cases were linked directly or indirectly to the Middle East region including Saudi Arabia, Jordan, Qatar, Oman, Kuwait, and UAE. MERS cases have also been reported in the later phases in the United Kingdom, France, Germany, Italy, Spain, and Tunisia. Most of these MERS cases were linked with the Middle East. The high mortality rates in family-based and hospital-based outbreaks were reported among patients with comorbidities such as diabetes and renal failure. MERS-CoV causes an acute, highly lethal pneumonia and renal dysfunction. The major complications reported in fatal cases are hyperkalemia with associated ventricular tachycardia, disseminated intravascular coagulation, pericarditis, and multiorgan failure. The case-fatality rate seems to be higher for MERS-CoV (around 30%) than for SARS-CoV (9.6%). The combination regimen of type 1 interferon + lopinavir/ritonavir is considered as the first-line therapy for MERS. Antiviral treatment is generally recommended for 10 to 14 days in patients with MERS-CoV infection. Convalescent plasma

  5. The impacts of Middle East dust on Indian summer rainfall

    NASA Astrophysics Data System (ADS)

    Jin, Q.; Yang, Z. L.; Wei, J.

    2014-12-01

    Using the Weather Research and Forecasting model with online chemistry (WRF-Chem), the impact of Middle East dust aerosols on the Indian summer monsoon rainfall was studied. Eight numerical experiments were conducted to take into account uncertainties related to dust-absorbing properties, various assumptions used in calculating aerosol optical depth (AOD), and various radiation schemes. In order to obtain reasonable dust emission, model-simulated AOD and radiation forcing at the top of the atmosphere were compared with multiple satellite- and surface-based observations. Consistent with observations, modeled results show heavy dust loadings in the Arabian Peninsula and Pakistan, which can be transported through long distance to the Arabian Sea and the Indian Peninsula. By heating the atmosphere in the lower troposphere over the Iranian Plateau, these dust aerosols result in strengthened Indian summer monsoon circulations, which in turn transport more water vapor to the Indian Peninsula. The model shows that northern India becomes wetter during the monsoon season in dust cases than non-dust cases. Further observational analyses show an increasing trend in AOD over the Arabian Peninsula, which corresponds to an increasing trend of rainfall in northern India during summer monsoon seasons from 2000 to 2013. These observed trends of AOD and rainfall are consistent with the model-simulated positive relationship between Middle East dust and Indian summer monsoon rainfall. Our results highlight long-term (decadal) impacts of Middle East dust aerosols on the Indian summer rainfall.

  6. Regional stratigraphy and petroleum geology, North Africa-Middle East

    SciTech Connect

    Peterson, J.A. )

    1991-03-01

    The North Africa-Middle East petroleum provinces are part of the broad sedimentary platform that occupied the northern and northeastern borders of the African-Arabian craton adjacent to the ancestral Hercynian (late Paleozoic) and subsequent Tethyan-Alpine oceans. Carbonate-clastic-evaporite sediments of infra-Cambrian through Holocene age were cyclically deposited in a relatively continuous belt around the eastern and northern borders of the craton, mainly on a broad, shallow-water platform adjacent to the proto-Tethys and Tethys seaway. The Paleozoic section reaches a substantial thickness in the subsurface of the Middle East and in northern Africa adjacent to the Mediterranean Sea, but all or part of it is absent because of nondeposition or erosion over much of the region. Post-Paleozoic deposition was more or less continuous across the entire craton border region in the Middle East and along the northern border of the Sahara platform in North Africa and in Somalia and eastern Ethiopia. Similar marine and associated sedimentary rock facies are present in all of these regions, although paleotectonic-stratigraphic interrelationships and continental paleolatitude positions have greatly affected petroleum generation and accumulation in the specific provinces along the craton border. A series of regional stratigraphic-sedimentary environment, and continental position, layer maps illustrates the relative influence of these factors through geologic time with respect to the relationship between petroleum reservoirs, source rocks, and confining rock facies.

  7. Respiratory disorders in the Middle East: a review.

    PubMed

    Waness, Abdelkarim; El-Sameed, Yaser Abu; Mahboub, Bassam; Noshi, Mohammed; Al-Jahdali, Hamdan; Vats, Mayank; Mehta, Atul C

    2011-07-01

    The spectrum of pulmonary pathology in the Middle East is as versatile as its civilizations and cultures. In this review, we outline the key challenges confronting pulmonologists in the Middle East. We shed light on the diverse conditions commonly encountered in the region, from the centuries-old illnesses of tuberculosis, to contemporary problems such as lung complications from chemical warfare. We specifically highlighted unique aspects related to respiratory illnesses in the Middle East, for example, climate factors in the desert region, cultural habits, for example, water-pipe smoking and disorders unique to the region, such as Behçet's disease. Pulmonologists are also faced with the consequences of modernization, including large immigrant population and associated social and health issues, rising incidence of obesity and sleep apnoea, and drug-resistant tuberculosis. Tackling these health issues will require an integrated approach involving public health, primary care as well as specialist pulmonology input, taking into consideration the unique cultural and environmental factors to ensure effective management and compliance to medical care. PMID:21564399

  8. Middle East: Slow year on the Gulf

    SciTech Connect

    Not Available

    1986-08-01

    This article surveys the petroleum outlook in the Middle East area. Observations include: Saudi Arabia's money crunch continues to keep the lid on exploration, production work; Abu Dhabi has also curtailed operations because of low oil prices, reduced budgets; Followup drilling has been disappointing around recent gas strikes in Sharjah, Dubai; Oman's aggressive EandP program will result in a 30% drilling increase this year; Kuwait isn't slowing down its development of light oil either; the goal is 40 new wells; Iran and Iraq are still boosting export capacities despite attacks on oil facilities; North Yemen's Alief field is a major find. Numerous structures remain to be drilled; Syria, Bahrain have development projects underway. Turkey is attracting U.S. majors.

  9. MODIS Views the Middle-East

    NASA Technical Reports Server (NTRS)

    2002-01-01

    To paraphrase English author T.H. White, borders are the one thing a man sees that a bird cannot see as it flies high overhead. For the 15th consecutive day, differences in ideology have sparked violence and tension in the middle-east as the rest of the world watches, concerned. This true-color image of the region was taken on September 10, 2000, by the MODerate-resolution Imaging Spectroradiometer (MODIS) flying aboard NASA's Terra spacecraft. The image shows the lands of Israel along the eastern shore of the Mediterranean Sea, with the countries of Jordan to the southeast and Syria to the Northeast. Jerusalem, labeled, is Israel's capital city and Aman, labeled, is the capital of Jordan. The region known as the West Bank lies between the two countries. Running from north to south, the Jordan River links the Sea of Galilee to the Dead Sea. Image courtesy Jacques Descloitres, MODIS Land Group, NASA GSFC

  10. GRACE water storage estimates for the Middle East and other regions with significant reservoir and lake storage

    NASA Astrophysics Data System (ADS)

    Longuevergne, L.; Wilson, C. R.; Scanlon, B. R.; Crétaux, J. F.

    2012-10-01

    While GRACE (Gravity Recovery and Climate Experiment) satellites are increasingly being used to monitor water storage changes globally, the impact of spatial distribution of water storage within a basin is generally ignored but may be substantial. In many basins, water may be stored in reservoirs, lakes, flooded areas, small aquifer systems, and other localized regions with sizes typically below GRACE resolution. The objective of this study was to assess the impact of non-uniform water storage distribution on GRACE estimates as basin-wide averages, focusing on surface water reservoirs. Analysis included numerical experiments testing the effect of mass size and position within a basin, and application to the Lower Nile (Lake Nasser) and Tigri-Euphrates (TE) basins as examples. Numerical experiments show that by assuming uniform mass distribution, GRACE estimates may under- or over-estimate basin-average water storage by up to a factor of two, depending on reservoir location and extent. Although their spatial extent may be unresolved by GRACE, reservoir storage may dominate in some basins. For example, it accounts for 95% of seasonal variations in the Lower Nile and 10% in the TE basins. Because reservoirs are used to mitigate droughts and buffer against climate extremes, their influence on interannual time scales can be large, for example accounting for 50% of total water storage decline during the 2007-2009 drought in the TE basin. Effects on GRACE estimates are not easily accounted for via simple multiplicative scaling, but in many cases independent information may be available to improve estimates. Accurate estimation of the reservoir contribution is critical, especially when separating groundwater from GRACE total water storage changes. Because the influence of spatially concentrated water storage - and more generally water distribution - is significant, GRACE estimates will be improved when it is possible to combine independent spatial distribution information

  11. Kicking up Sand in Middle-East Studies

    ERIC Educational Resources Information Center

    Byrne, Richard

    2008-01-01

    Professors who attended the Association for the Study of the Middle East and Africa (ASMEA) were alarmed about the state of Middle East studies. The group's co-founder, Bernard Lewis, said in his keynote address that the freedom to study and write on the topic of Islam was under assault by a Cerberus of "postmodernism," "political correctness,"…

  12. Books about the Middle East for Children and Youth.

    ERIC Educational Resources Information Center

    Kuntz, Patricia

    This bibliography comprises a list of 236 reviewed children's books about the Middle East. All books were published since 1970 in the United States. For the purpose of this document the countries of the Middle East number 16: Bahrain, Cyprus, Iraq, Iran, Israel, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, Syria, Turkey, United Arab…

  13. Middle East Geopolitical Transformation: The Disappearance of a Shatterbelt.

    ERIC Educational Resources Information Center

    Cohen, Saul B.

    1992-01-01

    Discusses the future of the Middle East in the wake of the end of the Cold War. Examines the ongoing political reorientation of the region. Suggests that the United States and Europe can foster a political balance in the Middle East by acting as competitive but allied stabilizers. (SG)

  14. A Global Perspective on Public Relations Ethics: The Middle East.

    ERIC Educational Resources Information Center

    Kruckeberg, Dean

    Sophisticated public relations is being practiced in the Middle East. However, the models used in that region are not identical to American models, nor are they identical to those in other Western countries usually considered part of the "First World." In particular, Moslem culture heavily influences Middle East practice. Can the ethics of public…

  15. Communication in the Middle East: A Basic Bibliography.

    ERIC Educational Resources Information Center

    Merriam, Allen H.

    This 48-item bibliography on communication in the Middle East includes books and journal articles published between 1951 and 1990. The bibliography includes materials dealing with Iran, Israel, Islam, media coverage of the Middle East, rhetorical strategies, and the rest of the Arab world. (RS)

  16. Middle East Respiratory Syndrome in 3 Persons, South Korea, 2015.

    PubMed

    Yang, Jeong-Sun; Park, SungHan; Kim, You-Jin; Kang, Hae Ji; Kim, Hak; Han, Young Woo; Lee, Han Saem; Kim, Dae-Won; Kim, A-Reum; Heo, Deok Rim; Kim, Joo Ae; Kim, Su Jin; Nam, Jeong-Gu; Jung, Hee-Dong; Cheong, Hyang-Min; Kim, Kisoon; Lee, Joo-Shil; Kim, Sung Soon

    2015-11-01

    In May 2015, Middle East respiratory syndrome coronavirus infection was laboratory confirmed in South Korea. Patients were a man who had visited the Middle East, his wife, and a man who shared a hospital room with the index patient. Rapid laboratory confirmation will facilitate subsequent prevention and control for imported cases. PMID:26488745

  17. The Middle East Institute Resource Guide for Teachers.

    ERIC Educational Resources Information Center

    Fix, Jerrold E.

    Abstracts and evaluations of over 50 instructional and resource materials related to the Middle East are presented in the resource guide. The guide is intended for use by elementary and secondary school social studies classroom teachers as they seek information about availability and potential uses of resources dealing with the Middle East. Four…

  18. GRACE water storage estimates for the Middle East and other regions with significant reservoir and lake storage

    NASA Astrophysics Data System (ADS)

    Longuevergne, L.; Wilson, C. R.; Scanlon, B. R.; Crétaux, J. F.

    2013-12-01

    While GRACE (Gravity Recovery and Climate Experiment) satellites are increasingly being used to monitor total water storage (TWS) changes globally, the impact of spatial distribution of water storage within a basin is generally ignored but may be substantial. In many basins, water is often stored in reservoirs or lakes, flooded areas, small aquifer systems, and other localized regions with areas typically below GRACE resolution (~200 000 km2). The objective of this study was to assess the impact of nonuniform water storage distribution on GRACE estimates of TWS changes as basin-wide averages, focusing on surface water reservoirs and using a priori information on reservoir storage from radar altimetry. Analysis included numerical experiments testing effects of location and areal extent of the localized mass (reservoirs) within a basin on basin-wide average water storage changes, and application to the lower Nile (Lake Nasser) and Tigris-Euphrates basins as examples. Numerical experiments show that by assuming uniform mass distribution, GRACE estimates may under- or overestimate basin-wide average water storage by up to a factor of ~2, depending on reservoir location and areal extent. Although reservoirs generally cover less than 1% of the basin area, and their spatial extent may be unresolved by GRACE, reservoir storage may dominate water storage changes in some basins. For example, reservoir storage accounts for ~95% of seasonal water storage changes in the lower Nile and 10% in the Tigris-Euphrates. Because reservoirs are used to mitigate droughts and buffer against climate extremes, their influence on interannual timescales can be large. For example, TWS decline during the 2007-2009 drought in the Tigris-Euphrates basin measured by GRACE was ~93 km3. Actual reservoir storage from satellite altimetry was limited to 27 km3, but their apparent impact on GRACE reached 45 km3, i.e., 50% of GRACE trend. Therefore, the actual impact of reservoirs would have been greatly

  19. Helicobacter pylori: the Middle East scenario.

    PubMed Central

    Novis, B. H.; Gabay, G.; Naftali, T.

    1998-01-01

    A review of Helicobacter pylori in the Middle East is presented. Prevalence studies have been performed in asymptomatic population groups from Algeria, Israel, Saudi Arabia and Turkey. These showed that the prevalence of H. pylori is similar to that of the developing countries of the world with a high level of infection in childhood (40 to 70 percent), which increases with age to 85 to 90 percent. Israel, however, has a low prevalence in children (10 percent), but there is a rapid rise in the second decade of life to 39 percent, reaching 79 percent in those over 60 years old. The prevalence rates were higher in those living in communal settlements (72 percent) than in urban dwellers (65 percent). The infection rates were higher in persons of Mediterranean and Asian origin (89 percent) compared to those of Western European/North American origin (57 percent). The prevalence rate of H. pylori infection in patients undergoing endoscopy for upper gastrointestinal symptoms has now been reported from many Middle Eastern countries, including Egypt, Iran, Israel, Oman, Saudi Arabia, the United Arab Emirates and Yemen. These studies showed that patients with gastritis and peptic ulcer disease had similar rates of infection as reported from Europe, United States and Africa (71 to 92 percent). However, patients with non-ulcer dyspepsia had higher rates of infection (61 to 89 percent). The H. pylori scenario from the prevalence rates, treatment protocols and responses to treatment does not differ very much from other developing areas of the world. PMID:10378359

  20. The rabies situation in the Middle East.

    PubMed

    Seimenis, A

    2008-01-01

    Rabies is a public health problem of significant importance in the majority of Southern and Eastern Mediterranean and Middle Eastern countries. In some of these countries, there is a considerable death rate due to rabies. Dogs are the main source of human infection, while cats constitute the second most important group of domestic animals followed by cattle, sheep, goats, camels, donkeys and then wild animals. There are around 300 reported human cases in these regions annually, with several hundred thousand post-exposure treatments. Laboratory confirmation of rabies cases is not always performed. In most countries, there is one central rabies diagnosis laboratory with trained staff and the diagnosis capability of district laboratories is weak. Animal rabies control consists of the vaccination of dogs and cats, the elimination of stray animals, health education for the public, etc. Mass vaccination of dogs is not implemented, and the effective coverage rate is not exactly known. The elimination of stray dogs and other animals by shooting and poisoning is still implemented in certain countries, however, this has a minimal effect on rabies transmission. Certain countries of the Middle East region are facing increasing problems due to wildlife rabies, including Saudi Arabia, Oman, Yemen, Israel, Iran and Turkey. The red fox (Vulpes vulpes) and golden jackal (Canis aureus) are usually involved. Coordinated actions to confront the serious rabies public health and economic problems should be undertaken by affected countries, with the assistance of international organisations, under conditions that are suitable for each country. PMID:18634465

  1. Oil, turmoil, and Islam in the Middle East

    SciTech Connect

    Sheikh, A.R.

    1986-01-01

    The turmoil and strife of the Middle East raises serious questions about the security of the world's oil supply. The author argues that OPEC and OAPEC can no longer afford to impose indiscriminate price increases on the marketplace because they hurt not only themselves but oil poor Third World nations as well. The author analyzes the importance of Middle Eastern oil in world politics. He emphasizes that any consideration of the forces influencing development in the Middle East should take Islamic tradition into account. Each chapter is organized around a current Middle Eastern problem: oil politics in relation to international energy needs; the ramifications of the new oil wealth and power of the Middle East; The Iran-Iraq War; Muslim insurgency in Afghanistan; The Arab-Israel conflict; turmoil in Lebanon; Palestinian nationalism; and the Middle East as a superpower.

  2. Pathogenesis of Middle East respiratory syndrome coronavirus.

    PubMed

    van den Brand, Judith M A; Smits, Saskia L; Haagmans, Bart L

    2015-01-01

    Human coronaviruses (CoVs) mostly cause a common cold that is mild and self-limiting. Zoonotic transmission of CoVs such as the recently identified Middle East respiratory syndrome (MERS)-CoV and severe acute respiratory syndrome (SARS)-CoV, on the other hand, may be associated with severe lower respiratory tract infection. This article reviews the clinical and pathological data available on MERS and compares it to SARS. Most importantly, chest radiographs and imaging results of patients with MERS show features that resemble the findings of organizing pneumonia, different from the lesions in SARS patients, which show fibrocellular intra-alveolar organization with a bronchiolitis obliterans organizing pneumonia-like pattern. These findings are in line with differences in the induction of cytopathological changes, induction of host gene responses and sensitivity to the antiviral effect of interferons in vitro when comparing both MERS-CoV and SARS-CoV. The challenge will be to translate these findings into an integrated picture of MERS pathogenesis in humans and to develop intervention strategies that will eventually allow the effective control of this newly emerging infectious disease.

  3. Wind Resource Assessment in the Middle East

    NASA Astrophysics Data System (ADS)

    Yip, C. M. A.; Gunturu, U. B.; Stenchikov, G. L.

    2014-12-01

    This study constructs wind power resource in the Middle East using the Modern Era Retrospective-Analysis for Research and Applications (MERRA) boundary layer flux data at 80m, 100m, and 120m. The resource is then characterized using robust metrics on abundance, variability, and intermittency of wind power density at separate heights. The analyses suggest high resource in western regions of Saudi Arabia, especially at the Red Sea and the mountainous regions away from the coastline. Southern coast of Oman and the Gulf of Aden also demonstrate high median wind power density. These corresponding high wind regions also exhibit high availability over the period of record length (1979-2013) as characterized by power density above 200W/m2, as well as similar behavior in episode length, which measures the persistence of the resource. These identified high wind regions differ in resource variability in terms of the coefficient of variation. The western mountainous regions of Saudi Arabia and the coastline of Oman show moderate variability compared to the Red Sea, where it sees two different regimes of variability, low in the north and high in the south. The Gulf of Aden demonstrates surprisingly low variability. Further statistical measures of variability, abundance, and intermittency will be elaborated. We will also discuss the geographical and meteorological factors controlling the wind resource in the region.

  4. Earthquake Model of the Middle East (EMME) Project: Active Fault Database for the Middle East Region

    NASA Astrophysics Data System (ADS)

    Gülen, L.; Wp2 Team

    2010-12-01

    The Earthquake Model of the Middle East (EMME) Project is a regional project of the umbrella GEM (Global Earthquake Model) project (http://www.emme-gem.org/). EMME project region includes Turkey, Georgia, Armenia, Azerbaijan, Syria, Lebanon, Jordan, Iran, Pakistan, and Afghanistan. Both EMME and SHARE projects overlap and Turkey becomes a bridge connecting the two projects. The Middle East region is tectonically and seismically very active part of the Alpine-Himalayan orogenic belt. Many major earthquakes have occurred in this region over the years causing casualties in the millions. The EMME project will use PSHA approach and the existing source models will be revised or modified by the incorporation of newly acquired data. More importantly the most distinguishing aspect of the EMME project from the previous ones will be its dynamic character. This very important characteristic is accomplished by the design of a flexible and scalable database that will permit continuous update, refinement, and analysis. A digital active fault map of the Middle East region is under construction in ArcGIS format. We are developing a database of fault parameters for active faults that are capable of generating earthquakes above a threshold magnitude of Mw≥5.5. Similar to the WGCEP-2007 and UCERF-2 projects, the EMME project database includes information on the geometry and rates of movement of faults in a “Fault Section Database”. The “Fault Section” concept has a physical significance, in that if one or more fault parameters change, a new fault section is defined along a fault zone. So far over 3,000 Fault Sections have been defined and parameterized for the Middle East region. A separate “Paleo-Sites Database” includes information on the timing and amounts of fault displacement for major fault zones. A digital reference library that includes the pdf files of the relevant papers, reports is also being prepared. Another task of the WP-2 of the EMME project is to prepare

  5. Ecology and distribution of Bulinus truncatus in the Middle East

    PubMed Central

    Watson, J. M.

    1958-01-01

    The author gives a comprehensive account of the present status of knowledge regarding the ecology and distribution of Bulinus truncatus, the intermediate host of Schistosoma haematobium in the Middle East and North Africa. He discusses in detail the types of habitat favoured by this snail, its life-cycle and seasonal variations in its populations, the effect of ecological factors on its distribution and occurrence, and the relationship between its control and its bionomics, stressing the many aspects of these subjects that require further investigation and suggesting lines for future research. In addition, the author outlines briefly the effect of some human activities (for example, extension of irrigation and agriculture), in their relationship to the snail host, on the incidence of bilharziasis haematobia in the Middle East and Africa. He concludes the paper with a summary of the three basic needs in respect of bilharziasis control: ecological research; prevention of pollution of waters with human excrement; and avoidance of human contact with infective water. PMID:13573115

  6. Drought is a recurring challenge in the Middle East

    PubMed Central

    Kaniewski, David; Van Campo, Elise; Weiss, Harvey

    2012-01-01

    Climate change and water availability in the Middle East are important in understanding human adaptive capacities in the face of long-term environmental changes. The key role of water availability for sedentary and nomad populations in these arid to semiarid landscapes is understood, but the millennium-scale influence of hydrologic instability on vegetation dynamics, human occupation, and historic land use are unknown, which has led to a stochastic view of population responses and adaptive capacities to precipitation anomalies. Within the time-frame of the last two global climate events, the Medieval Climate Anomaly and the Little Ice Age, we report hydrologic instability reconstructed from pollen-derived climate proxies recovered near Tell Leilan, at the Wadi Jarrah in the Khabur Plains of northeastern Syria, at the heart of ancient northern Mesopotamia. By coupling climate proxies with archaeological-historical data and a pollen-based record of agriculture, this integrative study suggests that variability in precipitation is a key factor on crop yields, productivity, and economic systems. It may also have been one of the main parameters controlling human settlement and population migrations at the century to millennial timescales in the arid to semiarid areas of the Middle East. An abrupt shift to drier conditions at ca. AD 1400 is contemporaneous with a change from sedentary village life to regional desertion and nomadization (sheep/camel pastoralists) during the preindustrial era in formerly Ottoman realms, and thereby adds climate change to the multiple causes for Ottoman Empire “decline.” PMID:22355126

  7. Drought is a recurring challenge in the Middle East.

    PubMed

    Kaniewski, David; Van Campo, Elise; Weiss, Harvey

    2012-03-01

    Climate change and water availability in the Middle East are important in understanding human adaptive capacities in the face of long-term environmental changes. The key role of water availability for sedentary and nomad populations in these arid to semiarid landscapes is understood, but the millennium-scale influence of hydrologic instability on vegetation dynamics, human occupation, and historic land use are unknown, which has led to a stochastic view of population responses and adaptive capacities to precipitation anomalies. Within the time-frame of the last two global climate events, the Medieval Climate Anomaly and the Little Ice Age, we report hydrologic instability reconstructed from pollen-derived climate proxies recovered near Tell Leilan, at the Wadi Jarrah in the Khabur Plains of northeastern Syria, at the heart of ancient northern Mesopotamia. By coupling climate proxies with archaeological-historical data and a pollen-based record of agriculture, this integrative study suggests that variability in precipitation is a key factor on crop yields, productivity, and economic systems. It may also have been one of the main parameters controlling human settlement and population migrations at the century to millennial timescales in the arid to semiarid areas of the Middle East. An abrupt shift to drier conditions at ca. AD 1400 is contemporaneous with a change from sedentary village life to regional desertion and nomadization (sheep/camel pastoralists) during the preindustrial era in formerly Ottoman realms, and thereby adds climate change to the multiple causes for Ottoman Empire "decline." PMID:22355126

  8. Suggested Activities for a Unit on the Middle East.

    ERIC Educational Resources Information Center

    Ediger, Marlow

    1983-01-01

    Student activities that focus on the different cultures and the history of the Middle East from Biblical times to the present are suggested. These include debates, art projects, slide shows, maps, and research problems. (IS)

  9. Night Pass over Central Africa and the Middle East

    NASA Video Gallery

    This video over Central Africa and the Middle East was taken by the crew of Expedition 29 aboard the International Space Station. This sequence of shots was taken on Oct. 1, 2011, from 21:20:24 to ...

  10. Evening Pass Over the Sahara Desert and the Middle East

    NASA Video Gallery

    This video over the Sahara Desert and the Middle East was taken by the crew of Expedition 29 aboard the International Space Station. This sequence of shots was taken on Oct. 6, 2011, from 19:46:23 ...

  11. A Review of Dietary Selenium Intake and Selenium Status in Europe and the Middle East

    PubMed Central

    Stoffaneller, Rita; Morse, Nancy L.

    2015-01-01

    This is a systematic review of existing data on dietary selenium (Se) intake and status for various population groups in Europe (including the United Kingdom (UK)) and the Middle East. It includes English language systematic reviews, meta-analyses, randomised controlled trials, cohort studies, cross-sectional and case-control studies obtained through PUBMED searches from January, 2002, to November, 2014, for European data and from 1990 to November 2014, for Middle Eastern data. Reports were selected if they included data on Se intake and status. The search identified 19 European/UK studies and 15 investigations in the Middle East that reported Se intake and Se concentration in water and/or food and 48 European/UK studies and 44 investigations in the Middle East reporting Se status. Suboptimal Se status was reported to be widespread throughout Europe, the UK and the Middle East, and these results agreed with previous reports highlighting the problem. Eastern European countries had lower Se intake than Western European countries. Middle Eastern studies provided varying results, possibly due to varying food habits and imports in different regions and within differing socioeconomic groups. In conclusion, Se intake and status is suboptimal in European and Middle Eastern countries, with less consistency in the Middle East. PMID:25734564

  12. The Middle East: An Annotated Bibliography of Literature for Children.

    ERIC Educational Resources Information Center

    Maehr, Jane

    This is an annotated bibliography of folklore, fiction and nonfiction about the Middle East, written in English for children aged 5 and older. There are eleven chapters - one which focuses on the entire Middle Eastern region, and ten which deal with individual countries: Iran, Iraq, Israel, Jordan, Kuwait, Lebanon, Saudi Arabia, Syria, Turkey, and…

  13. Middle East Studies: A Catalogue of Middle East Studies Resources In or Near Connecticut. Area Studies Resource Guides, Number Two.

    ERIC Educational Resources Information Center

    Stone, Frank A., Comp.

    This directory of Middle Eastern resource materials in or near Connecticut is designed for use by educators, librarians, media specialists, and the general public. The Middle East is defined as the part of the world known as Southwest Asia/North Africa (SWANA). The information is organized under ten major categories: associations and…

  14. SSA 02-1 SALT AND HYPERTENSION IN MIDDLE EAST.

    PubMed

    Arici, Mustafa

    2016-09-01

    Middle East and Eastern Mediterranean Region (EMR) is a transcontinental region centered on Western Asia, east of the Mediterranean Sea and the Egypt. The whole area has almost 20 countries with an approximate population of 400 million with different ethnicities. The whole area has basically a hot and dry climate. In some parts of the Middle East, there is a desert climate.Cardiovascular diseases were the leading causes of death in the Middle East, similar to the many other territories of the World. Beyond that, the World Health Organization (WHO) has recognized this region as a hotspot for cardiovascular disease, where disease projections will exceed those of other regions. The major reason for this is the great epidemiological transition in these countries. There is a great prevalence of smoking, increasing obesity, and a change in dietary patterns, as well, from traditional to ones higher in calories and processed foods.Diets high in salt increase blood pressure levels that are the leading contributor to cardiovascular disease mortality. Hypertension is very prevalent in the EMR and the Middle East. The average hypertension prevalence in this territory is around 30% and unawareness, untreated and uncontrolled hypertension rates were very high. Middle East ranks on the top levels for high salt intake compared to many other territories. The global salt consumption analysis showed that average sodium intake ranges from 3.74 to 4.12 grams of sodium per day in the Middle East. This corresponds to 9.35 to 10.3 grams of salt per day. This amount was nearly twice the WHO recommended limit of 5 g/day. Estimated intakes in Middle East countries were also diverse, ranging from 7,8 grams of salt per day in Lebanon to 15 grams of salt per day in Turkey.It is well known that decreasing dietary salt intake from 10 grams to 5 grams per day could reduce cardiovascular diseases rate by 17% worldwide. Several analyses have also showed that salt reduction strategies will be cost

  15. SSA 02-1 SALT AND HYPERTENSION IN MIDDLE EAST.

    PubMed

    Arici, Mustafa

    2016-09-01

    Middle East and Eastern Mediterranean Region (EMR) is a transcontinental region centered on Western Asia, east of the Mediterranean Sea and the Egypt. The whole area has almost 20 countries with an approximate population of 400 million with different ethnicities. The whole area has basically a hot and dry climate. In some parts of the Middle East, there is a desert climate.Cardiovascular diseases were the leading causes of death in the Middle East, similar to the many other territories of the World. Beyond that, the World Health Organization (WHO) has recognized this region as a hotspot for cardiovascular disease, where disease projections will exceed those of other regions. The major reason for this is the great epidemiological transition in these countries. There is a great prevalence of smoking, increasing obesity, and a change in dietary patterns, as well, from traditional to ones higher in calories and processed foods.Diets high in salt increase blood pressure levels that are the leading contributor to cardiovascular disease mortality. Hypertension is very prevalent in the EMR and the Middle East. The average hypertension prevalence in this territory is around 30% and unawareness, untreated and uncontrolled hypertension rates were very high. Middle East ranks on the top levels for high salt intake compared to many other territories. The global salt consumption analysis showed that average sodium intake ranges from 3.74 to 4.12 grams of sodium per day in the Middle East. This corresponds to 9.35 to 10.3 grams of salt per day. This amount was nearly twice the WHO recommended limit of 5 g/day. Estimated intakes in Middle East countries were also diverse, ranging from 7,8 grams of salt per day in Lebanon to 15 grams of salt per day in Turkey.It is well known that decreasing dietary salt intake from 10 grams to 5 grams per day could reduce cardiovascular diseases rate by 17% worldwide. Several analyses have also showed that salt reduction strategies will be cost

  16. Middle East respiratory syndrome: what clinicians need to know.

    PubMed

    Sampathkumar, Priya

    2014-08-01

    A severe viral illness caused by a newly discovered coronavirus was first reported in the Middle East in 2012. The virus has since been named the Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV cases have been reported in several countries around the world in travelers from the Middle East. The illness has a high mortality rate. Limited human-to-human transmission has occurred including transmission to health care workers. The source of the virus remains unclear, but camels are a possible source. Two unrelated imported cases of MERS-CoV have been reported in the United States. Neither a vaccine nor effective therapy against the virus is available. International cooperation and information sharing will be key to understanding and ending the MERS-CoV outbreak. PMID:25034307

  17. Oil and gas developments in Middle East in 1986

    SciTech Connect

    Hemer, D.O.; Gohrbandt, K.H.A.

    1987-10-01

    Petroleum production in Middle East countries during 1986 totaled 4,493,973,000 bbl (an average rate of 12,312,254 BOPD), up 22.3% from the revised 1985 total of 3,673,729,000 bbl. Iraq, Kuwait, Saudi Arabia, Abu Dhabi, and Oman had significant increased; Iran was the only Middle East country with a significant decrease. New fields went on production in Oman and Yemen Arab Republic, and significant discoveries were reported in Iraq, Yemen Arab Republic, Oman, and Syria. However, exploration was generally down in most countries. Exploration and production operations continued to be affected by war in Iraq and Iran. 8 figures, 7 tables.

  18. Language Teacher Research in the Middle East

    ERIC Educational Resources Information Center

    Coombe, Christine, Ed.; Barlow, Lisa, Ed.

    2007-01-01

    An openness to new ways of teaching and learning is vital for growth among English language teachers, teacher educators, teachers in training, and students. This volume in the Language Teacher Research Series (Thomas S. C. Farrell, series editor) shares the studies and reflections of teacher researchers working in Middle Eastern countries with…

  19. Evaluating Land Information System (LIS) capabilities in simulating the water budget and surface water dynamics over data-scarce areas in the Middle East

    NASA Astrophysics Data System (ADS)

    Getirana, A.; Jung, H. C.; McNally, A.; Peters-Lidard, C. D.; Cretaux, J. F.

    2015-12-01

    Despite recent advances in land surface modeling and remote sensing, estimates of the global water budget are still fairly uncertain. Uncertainties are particularly high in areas where data for model calibration and evaluation are scarce or unavailable. This study presents recent developments in the hydrological modeling over the Tigris-Euphrates River basin. An intercomparison effort is performed in order to determine how models and meteorological forcings represent physical processes. In this sense, multiple experiments are performed using state-of-the-art capabilities implemented in the NASA Land Information System (LIS). The NASA Modern Era Retrospective Reanalysis for Applications (MERRA) and Global Data Assimilation System (GDAS) meteorological datasets are used as main forcings. Additional experiments are performed replacing their precipitation with the Climate Hazards Group Infra-Red Precipitation with Stations (CHIRPS) dataset. Both Catchment and Noah land surface models coupled with the Hydrological Modeling and Analysis Platform (HyMAP) river routing scheme are considered to simulate the water budget and surface water dynamics. Due to the scarce ground-based data availability, satellite-based estimates of the terrestrial water storage, evapotranspiration, water level and floodplain extent are used as complimentary information to evaluate the hydrological behavior in the basin. In particular, the water shortage observed in 2015 in that region is analyzed based on model outputs. Finally, we discuss prospects and challenges in considering anthropogenic impacts (irrigation and dams) on the hydrological modeling of the basin.

  20. Middle East Regional Irrigation Management Information Systems project-Some science products

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Similarities in the aridity of environments and water scarcity for irrigation allow common approaches to irrigation management problems and research methods in the Southern Great Plains of the United States and the Middle East. Measurement methods involving weighing lysimeters and eddy covariance sy...

  1. Education in the Broader Middle East: Borrowing a Baroque Arsenal

    ERIC Educational Resources Information Center

    Donn, Gari, Ed.; Al Manthri, Yahya, Ed.

    2013-01-01

    This book brings together academics and postgraduate students, practitioners and Ministry officials all of whom are wedded to developing an understanding of what is happening to education in the broader Middle East. They cover many countries whilst recognising that many more could have been included. In drawing attention to education in Pakistan,…

  2. Literature from the Modern Middle East: Making a Living Connection

    ERIC Educational Resources Information Center

    Webb, Allen

    2009-01-01

    While the United States is deeply involved in the Middle East, most Americans, including students, lack knowledge about the region. Yet from Afghanistan to Palestine, from Morocco to Iraq, there is a vibrant and exciting literature by living authors that can bring the diverse experiences and perspectives of this vital part of the world to classes.…

  3. Aspects of Education in the Middle East and North Africa

    ERIC Educational Resources Information Center

    Brock, Colin, Ed.; Levers, Lila Zia

    2007-01-01

    The chapters in this volume do not represent the whole of the Middle East and North Africa, as such a collection would have been too large for one volume. Rather, the selection here is intended to present different perspectives on a range of educational issues, relevant to a particular focus or country, or common to a number of countries in the…

  4. Sprue in the Middle East: five case reports

    PubMed Central

    Haeney, M. R.; Montgomery, R. D.; Schneider, R.

    1974-01-01

    Tropical sprue is a well documented condition with a special geographical distribution. This paper describes five patients with unexplained malabsorption whose symptoms began during a period of residence in the Middle East or Mediterranean areas. ImagesFig 4Fig 6 PMID:18668847

  5. Persistence of Antibodies against Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Iblan, Ibrahim; Rha, Brian; Alqasrawi, Sultan; Haddadin, Aktham; Al Nsour, Mohannad; Alsanouri, Tarek; Ali, Sami Sheikh; Harcourt, Jennifer; Miao, Congrong; Tamin, Azaibi; Gerber, Susan I.; Haynes, Lia M.; Al Abdallat, Mohammad Mousa

    2016-01-01

    To determine how long antibodies against Middle East respiratory syndrome coronavirus persist, we measured long-term antibody responses among persons serologically positive or indeterminate after a 2012 outbreak in Jordan. Antibodies, including neutralizing antibodies, were detectable in 6 (86%) of 7 persons for at least 34 months after the outbreak. PMID:27332149

  6. Agrarian Reform Policies and Development in the Arab Middle East.

    ERIC Educational Resources Information Center

    Baali, Fuad

    The purpose of this paper is to analyze and evaluate the nature, scope, and implications of the rural development in the Arab countries of the Middle East and North Africa. The first section of the paper deals with the forces that have caused changes in agrarian reform policies as they affected rural development in these countries. Specifically…

  7. Deconstructing the Other: Teaching Politics of the Middle East.

    ERIC Educational Resources Information Center

    Tetreault, Mary Ann

    1996-01-01

    Discusses strategies aimed at moving undergraduates beyond the traditional stereotypical and demonized portrait of the Middle East. Suggests focusing on boundaries (shifting between national, cultural, religious, and economic), on bases of information (different students bring different knowledge levels), and using a wide variety of biographies…

  8. Archaeologists' Group Proposes Safekeeping of Middle East Artifacts

    ERIC Educational Resources Information Center

    Kalman, Matthew

    2008-01-01

    Israeli, Palestinian, and American archaeologists unveiled a draft agreement on archaeological and cultural heritage that they hope to see included in a future Middle East peace agreement. Presenting their proposal to an audience of archaeologists at the Van Leer Jerusalem Institute, they said it was the first time that Israelis and Palestinians…

  9. Cooperative monitoring workshop: Focus on the Middle East

    SciTech Connect

    Pregenzer, A.L.; Vannoni, M.; Biringer, K.; Dobranich, P.

    1995-05-01

    Sandia National Laboratories and the Institute for Global Conflict and Cooperation hosted a workshop on the application of cooperative monitoring to the Middle East. The workshop, held in Albuquerque, New Mexico, from July 17 through 21, 1994, was sponsored by the US Department of Energy, the Arms Control and Disarmament Agency, and the US Department of State. The meeting, which focused on use of technical monitoring tools and sharing of collected information to facilitate regional agreements, included participants from five regional countries as well as from American universities, the US government, and US National Laboratories. Some attendees previously participated in meetings of the Arms Control and Regional Security working group of the Middle East Multilateral Peace Talks. The workshop combined presentations, demonstrations and hands-on experimentation with monitoring hardware and software. An exercise was conducted to evaluate and recommend cooperative monitoring options for a model agreement between two hypothetical countries. Historical precedents were reviewed and the role of environmental and natural resource conflicts explored. These activities were supplemented by roundtable discussions covering Middle East security issues, the relationship of ``national means`` to cooperative monitoring, and cooperative monitoring of ballistic missiles in the Middle East.

  10. Relighting the Torch: East Middle School's OA Success Story.

    ERIC Educational Resources Information Center

    Pokorny, Nancy

    1995-01-01

    Describes the implementation of outcomes accreditation at East Middle School, in Aurora, Colorado. Reports significant gains in student success, including a 68% decline in student tardiness and a 60% decrease in suspensions. Indicates that the school was selected as a state Governor's Challenger School. (MAB)

  11. Transnational Higher Education: Offshore Campuses in the Middle East

    ERIC Educational Resources Information Center

    Miller-Idriss, Cynthia; Hanauer, Elizabeth

    2011-01-01

    This paper maps the landscape of transnational higher education in the Middle East, focusing in particular on the recent expansion of satellite, branch, and offshore educational institutions and programs that foreign institutions have set up in the region. Of the estimated 100 branch campuses currently operating worldwide, over one-third are in…

  12. United States security strategy for the Middle East

    SciTech Connect

    1995-05-01

    One of the most controversial questions the United States faces in the aftermath of the Cold War is when to use military force in this complex world. But there is little dispute that we must be prepared to use force to defend our vital interests: when the survival of the United States or its key allies is in danger, when our critical economic interests are threatened, or when dealing with the emergence of a future nuclear threat. Nowhere are these criteria met more clearly than in the Middle East. This report is the second in a series of regional reports undertaken by the Assistant Secretary of Defense for International Security Affairs with the aim of defining U.S. interests and commitments in critical parts of the world. It outlines a strategy for promoting stability and peaceful change through a combination of diplomacy, peacetime engagement, forward presence, and rapid response capabilities. It also explains how we can carry out this strategy without formal alliances or permanent basing arrangements that are familiar elsewhere in the world. The prospects for stability in the Middle East in the coming decades are mixed. On the positive side, unprecedented progress has recently been made in the Middle East peace process, holding forth the hope that Israelis and Palestinians alike can finally be integrated fully into the political and economic life of the Middle East. Furthermore, U.S. capabilities to defend its vital interests in the Middle East are at an all-time high, in stark contrast to the situation less than two decades ago.

  13. [Impacts of urbanization on the water quality and macrobenthos community structure of the tributaries in middle reach of Qiantang River, East China].

    PubMed

    Liu, Dong-Xiao; Yu, Hai-Yan; Liu, Shuo-Ru; Hu, Zun-Ying; Yu, Jian; Wang, Bei-Xin

    2012-05-01

    The 59 1st-3rd order tributaries in the middle reach of Qiantang River are negatively affected by different intensities of urbanization. In April 2010, an investigation was conducted on the water bodies' physical and chemical properties and macrobenthos communities of the tributaries, with the relationships between the tributaries' water quality and biological communities and the percentage of ground surface impervious area (PIA), an indicator of urbanization intensity. The Spearman correlation analysis showed that the water bodies' NH(4+)-N, PO4(3-)-P, TP, COD(Mn), conductivity, width, depth, and fine sand/silt ratio were positively correlated with PIA, and negatively correlated with forest land area. The fitted nonlinear regression equations revealed that all the test macro-benthic invertebrate's parameters had significant relationships with PIA, of which, the total number of taxa, Shannon diversity index, richness index, EPT (%), predators (%), shredders (%), filterers (%) and scrapers (%) were negatively correlated to PIA but positively correlated to forest land area, and the BI, collectors (%), tolerance taxa (%) and oligochaeta (%) were positively correlated to the PIA. Our study indicated that under the impact of urbanization, these tributaries presented the common features of degradation, i. e., high concentrations of nitrogen and phosphorus, degradation of physical habitat, disappearance of pollution-sensitive macro-benthic invertebrate species, and dramatic increase of pollution-tolerant species individuals.

  14. Freshwater Losses In The Middle East

    NASA Video Gallery

    › Related story› Download video in HD formatsThe visualization shows variations in total water storage from normal,in millimeters, in the Tigris and Euphrates river basins, as measuredby N...

  15. Idiopathic intracranial hypertension in the Middle East: A growing concern

    PubMed Central

    Almarzouqi, Sumayya J.; Morgan, Michael L.; Lee, Andrew G.

    2014-01-01

    Idiopathic Intracranial Hypertension (IIH) is a disorder of increased intracranial pressure without any identifiable etiology. It is defined by elevated intracranial pressure (ICP) with normal neuroimaging and normal cerebrospinal fluid (CSF) contents. IIH typically affects young obese women and produces symptoms and signs related to high ICP. Headache and blurred vision are the most common symptoms, and papilledema is the major clinical sign. In this review we examine the epidemiology and demographic features of IIH in Middle Eastern countries and compare and contrast them with the published IIH literature from Western countries. The incidence of IIH in several Middle East countries has been estimated at 2.02–2.2/100,000 in the general population, which is higher than the Western rate. Obesity is a major risk factor globally and it is associated with an increased risk of severe vision loss due to IIH. There has been an increase in obesity prevalence in the Middle East countries mainly affecting the Gulf Council Countries (GCC), which parallels increased industrial development. This rise may be contributing to the increasing incidence of IIH in these countries. Other risk factors may also be contributing to IIH in Middle East countries and the differences and similarities to Western IIH merit further study. PMID:25859136

  16. Oil and turmoil: America faces OPEC and the Middle East

    SciTech Connect

    Rustow, D.A.

    1982-01-01

    Middle-East expert Rustow traces the chain of events that placed economic power in an unstable region. He recounts how European imperialists acquired and surrendered their positions of domination, how nationalists such as Nasser and Qaddafi sought to manipulate the superpowers, and how leaders such as Sadat and Begin wrestled with war and peace. Meanwhile, the oil industry's Seven Sisters lost their preeminence as OPEC grew from a loose confederacy of oil shiekdoms into a cartel strong enough to shake the world economy. Rustow analyzes the confusion in oil-consuming countries that led to long gasoline lines one year and talk of an oil glut and OPEC's collapse the next. He puts into context Washington's uneven efforts to bring stability to the strife-torn Middle East. 221 references, 3 figures, 7 tables.

  17. Leishmaniasis in the Middle East: Incidence and Epidemiology

    PubMed Central

    Salam, Nasir; Al-Shaqha, Waleed Mohammed; Azzi, Arezki

    2014-01-01

    Leishmaniasis is a major health problem worldwide, with several countries reporting cases of leishmaniasis resulting in loss of human life or a lifelong stigma because of bodily scars. The Middle East is endemic for cutaneous leishmaniasis, with countries like Syria reporting very high incidence of the disease. Despite several countries establishing national control programs for containing the sandfly vector and treatment of infection, the disease continues to spread. In addition to the endemicity of the region for leishmaniasis, the Middle East has seen a great deal of human migration either for earning of livelihood or due to political upheaval in the region. These factors contribute to the spread and proliferation of the causative species Leishmania and its sandfly host. This review discusses the current epidemiological scenario in Iraq, Syria, Saudi Arabia, and Jordan, emphasizing the number of cases reported, vector species, Leishmania species, and treatment available. The data is primarily from WHO reports for each country and current and old literature. PMID:25275483

  18. Active Faults and Seismic Sources of the Middle East Region: Earthquake Model of the Middle East (EMME) Project

    NASA Astrophysics Data System (ADS)

    Gulen, L.; EMME WP2 Team*

    2011-12-01

    The Earthquake Model of the Middle East (EMME) Project is a regional project of the GEM (Global Earthquake Model) project (http://www.emme-gem.org/). The EMME project covers Turkey, Georgia, Armenia, Azerbaijan, Syria, Lebanon, Jordan, Iran, Pakistan, and Afghanistan. Both EMME and SHARE projects overlap and Turkey becomes a bridge connecting the two projects. The Middle East region is tectonically and seismically very active part of the Alpine-Himalayan orogenic belt. Many major earthquakes have occurred in this region over the years causing casualties in the millions. The EMME project consists of three main modules: hazard, risk, and socio-economic modules. The EMME project uses PSHA approach for earthquake hazard and the existing source models have been revised or modified by the incorporation of newly acquired data. The most distinguishing aspect of the EMME project from the previous ones is its dynamic character. This very important characteristic is accomplished by the design of a flexible and scalable database that permits continuous update, refinement, and analysis. An up-to-date earthquake catalog of the Middle East region has been prepared and declustered by the WP1 team. EMME WP2 team has prepared a digital active fault map of the Middle East region in ArcGIS format. We have constructed a database of fault parameters for active faults that are capable of generating earthquakes above a threshold magnitude of Mw≥5.5. The EMME project database includes information on the geometry and rates of movement of faults in a "Fault Section Database", which contains 36 entries for each fault section. The "Fault Section" concept has a physical significance, in that if one or more fault parameters change, a new fault section is defined along a fault zone. So far 6,991 Fault Sections have been defined and 83,402 km of faults are fully parameterized in the Middle East region. A separate "Paleo-Sites Database" includes information on the timing and amounts of fault

  19. Oil and gas developments in Middle East in 1982

    SciTech Connect

    Hemer, D.O.; Hatch, G.C.

    1983-10-01

    Petroleum production in Middle East countries during 1982 totaled 4,499,464,000 bbl (an average rate of 12,162,915 BOPD), down 21.5% from 1981. Increases were in Iraq, Iran, and Oman. Significant decreases occurred in Kuwait, Divided Neutral Zone, Saudi Arabia, Qatar, and Abu Dhabi. New discoveries were reported in Oman, Syria, Abu Dhabi, Dubai, Iran, and Saudi Arabia.

  20. Petroleum developments in Middle East countries in 1979

    SciTech Connect

    Hemer, D.O.; Mason, J.F.; Hatch, G.C.

    1980-11-01

    Petroleum production in Middle East countries in 1979 totaled 7,779,619,000 bbl at an average rate of 21,314,024 b/d, up 0.4% from 1978. Principal increases were in Iraq, Kuwait, Divided Neutral Zone, and Saudi Arabia. Significant new discoveries were made in Saudi Arabia, Oman, and Abu Dhabi. New areas were explored in Oman, Syria, offshore South Yemen, Dubai, and Qatar.

  1. Saved Lives at Risk in the Middle East.

    PubMed

    Skouri, Hadi; Shurrab, Mohammed; Haj-Yahia, Saleem

    2016-01-01

    In the Middle East, heart failure prevalence seems to be high as the rest of the world. Few countries in the region recently have started implanting left ventricular assist devices (LVADs), basically as destination therapy. Terrorism and terrorist activities have been expanded worldwide especially in this part of the world. We present a case that highlights the relation between suicide bombers and LVAD patients. PMID:26735560

  2. A new inventory for middle east dust source points.

    PubMed

    Moridnejad, Ali; Karimi, Neamat; Ariya, Parisa A

    2015-09-01

    We use the Moderate Resolution Imaging Spectroradiometer (MODIS) sensor on both Terra and Aqua satellites to present new high-resolution mapping of major atmospheric dust source points in the Middle East region on the basis of the improved version of the recently developed Middle East Dust Index (MEDI) applied to 70 dust storms, which occurred during the period between 2001 and 2012. Results indicate that 247 different source points have participated in dust storm generation in the Middle East region in which Iraq and Syria are the highest efficient sites for dust storm generation in this region, respectively. Using extracted indices for Deep Blue algorithm, identified dust sources were classified into three levels of intensity. The frequency of occurrence approach, the relationship between high atmospheric dust content and its number of occurrences, is also used to identify sensitive source points. High-intensity dust storms are mainly located west of Iraq and the border of Iraq and Syria. We will discuss the implications of our results in understanding the global dust cycle. PMID:26297415

  3. Diasporic dreaming: return reproductive tourism to the Middle East.

    PubMed

    Inhorn, Marcia C

    2011-11-01

    This article attempts to capture the dynamics of return reproductive tourism to the Middle East, based on ethnographic research undertaken at four different Middle Eastern locales (Egypt, Lebanon, United Arab Emirates and Arab America). Across the Middle Eastern diaspora, which is now vast, due to the disruptions of war and political violence, infertile couples often dream of making a test-tube baby 'back home' for a variety of cultural, moral and psychological reasons. These reasons – including medical expatriotism, the language of medicine, co-religion and moral trustworthiness, donor phenotype, the comforts of home and discrimination – are rarely highlighted in the scholarly literature on cross-border reproductive care. Thus, further empirical investigation is needed in order to assess additional reasons for reproductive travel beyond Euro-America. Of particular concern are the needs of 'stranded' refugee populations, who are constrained from seeking assisted reproduction technology 'back home', but who may face economic constraints and cultural discrimination in host communities.

  4. Emerging diseases of Africa and the Middle East.

    PubMed

    Rweyemamu, M; Paskin, R; Benkirane, A; Martin, V; Roeder, P; Wojciechowski, K

    2000-01-01

    The term "emerging diseases" has been used recently to refer to different scenarios, all of which indicate changes in the dynamics of disease in the population. Of the OIE List A diseases, major changes have been experienced with rinderpest, peste des petit ruminants (PPR), contagious bovine pleuropneumonia (CBPP), foot-and-mouth disease, African swine fever, lumpy skin disease, and Rift Valley fever. Rinderpest represents a success story of the 1990s, thanks to the programs of the Pan African Rinderpest Campaign (PARC). The situation has changed from that of the 1980s when rinderpest was widespread throughout most of Tropical Africa and the Middle East. PPR is a disease that has become of increasing importance throughout Tropical Africa and the Middle East. CBPP, which had previously been reduced to sporadic incidence within endemic areas, invaded new areas, causing heavy mortality. African swine fever has extended to West Africa and to Madagascar, in both regions resulting in heavy losses. Climatic changes in both East and West Africa were associated with an upsurge of Rift Valley fever. Deficiencies in national veterinary services have contributed to failures in early detection and response; in many regions investigation and diagnosis services have deteriorated. The continuing structural adjustment program for national veterinary services will need to take into account their transformation from providers of services (e.g., vaccinations, medicines) to inspection and quality assurance services. Surveillance, early warning, and disease emergency preparedness will need to be pursued more vigorously in Africa and the Middle East as vital components of national veterinary services.

  5. Oil jobs have big impact on heavily populated Middle East.

    PubMed

    Omran, A R; Roudi, F

    1993-09-01

    Labor force interdependence creates a complex pattern among countries in the Middle East. Oil-rich countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates) must import two-thirds of their labor force, including 80% of their professional and technical workers. These migrant workers come from Egypt (60%), Jordan, Yemen, Sudan, and South Asia, and the money they send home is a major factor in the economies of their native lands. Many Arabs who are considered foreign laborers have spent their entire lives, or have even been born, in the oil-rich countries; they have no hope of attaining citizenship. South Asians compete with Arabs for work in the Gulf States and tend to accept less-desirable jobs and lower wages. South Asian workers migrate from Bangladesh, India, Pakistan, Sri Lanka, Indonesia, Korea, the Philippines, and Thailand. Middle Eastern women have social constraints on labor force participation, and most of the women working n the Gulf States are Asian; they often work as domestics. The women of the Middle East are an untapped resource for this labor market. PMID:12286978

  6. Oil jobs have big impact on heavily populated Middle East.

    PubMed

    Omran, A R; Roudi, F

    1993-09-01

    Labor force interdependence creates a complex pattern among countries in the Middle East. Oil-rich countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates) must import two-thirds of their labor force, including 80% of their professional and technical workers. These migrant workers come from Egypt (60%), Jordan, Yemen, Sudan, and South Asia, and the money they send home is a major factor in the economies of their native lands. Many Arabs who are considered foreign laborers have spent their entire lives, or have even been born, in the oil-rich countries; they have no hope of attaining citizenship. South Asians compete with Arabs for work in the Gulf States and tend to accept less-desirable jobs and lower wages. South Asian workers migrate from Bangladesh, India, Pakistan, Sri Lanka, Indonesia, Korea, the Philippines, and Thailand. Middle Eastern women have social constraints on labor force participation, and most of the women working n the Gulf States are Asian; they often work as domestics. The women of the Middle East are an untapped resource for this labor market.

  7. Oil and gas developments in Middle East in 1985

    SciTech Connect

    Hemer, D.O.; Gohrbandt, K.H.A.

    1986-10-01

    Petroleum production in Middle East countries during 1985 totaled 3,837,580,000 bbl (an average rate of 10,513,917 BOPD), down 2.2% from the revised 1984 total of 3,924,034,000 bbl. Iran, Iraq, Dubai, Oman, and Syria had significant increases; Kuwait, Kuwait-Saudi Arabia Divided Neutral Zone, Saudi Arabia, and Qatar had significant decreases. New fields went on production in Iraq, Abu Dhabi, Oman, and Syria. In North Yemen, the first ever oil production in that country was nearing the start-up stage at year end. 9 figures, 9 tables.

  8. Oil and gas developments in Middle East in 1984

    SciTech Connect

    Hemer, D.O.; Lyle, J.H.

    1985-10-01

    Petroleum production in Middle East countries during 1984 totaled 4,088,853,000 bbl (an average rate of 11,144,407 BOPD), down less than 1.0% from the revised total of 4,112,116,000 bbl produced in 1983. Iraq, Kuwait, Qatar, and Oman had significant increases; Iran and Dubai had significant decreases. Jordan produced oil, although a minor amount, for the first time ever, and new production facilities were in the planning stage in Syria, North Yemen, and Oman, which will bring new fields on stream when completed. 4 figures, 9 tables.

  9. Oil and gas developments in Middle East in 1984

    SciTech Connect

    Hemer, D.O.; Lyle, J.H.

    1985-10-01

    Petroleum production in Middle East countries during 1984 totaled 4,088,853,000 bbl (an average rate of 11,144,407 BOPD), down less than 1.0% from the revised total of 4,112,116,000 bbl produced in 1983. Iraq, Kuwait, Qatar, and Oman had significant increases; Iran and Dubai had significant decreases. Jordan produced oil, although a minor amount, for the first time ever, and new production facilities were in the planning stage in Syria, North Yemen, and Oman, which will bring new fields on stream when completed.

  10. Middle East respiratory syndrome: A new global threat

    PubMed Central

    Bhatia, Pradeep Kumar; Sethi, Priyanka; Gupta, Neeraj; Biyani, Ghansham

    2016-01-01

    The outbreak of Middle East respiratory syndrome (MERS) is reported from Saudi Arabia and the Republic of Korea. It is a respiratory disease caused by coronavirus. Camels are considered as a source for MERS transmission in humans, although the exact source is unknown. Human-to-human transmission is reported in the community with droplet and contact spread being the possible modes. Most patients without any underlying diseases remain asymptomatic or develop mild clinical disease, but some patients require critical care for mechanical ventilation, dialysis and other organ support. MERS is a disease with pandemic potential and awareness, and surveillance can prevent such further outbreaks. PMID:27013745

  11. Organ donation--world experience; the Middle East.

    PubMed

    Daar, A S

    1991-10-01

    Many countries in the Middle East began renal transplantation in the late 1970s and the 1980s. In many countries transplantation has evolved through distinct stages of development, and at present living-related donors continue to be the main source of kidneys. Islamic opinion has been strongly in favour of transplantation of organs from both living and cadaveric donors. Brain death as a criterion of death was accepted by Islamic Jurists in 1986, and in Saudi Arabia about 35% of all transplants are from cadaveric donors. Some patients continue to go to neighbouring countries to buy kidneys for transplantation; there is evidence that this practice has resulted in unacceptable morbidity and mortality, and is currently associated with a risk of at least 1:18 of acquiring HIV infection. Extrarenal solid organ transplantation is very new, with heart transplants being performed in Turkey, Jordan, and Saudi Arabia. Liver transplants have been initiated in Turkey and Kuwait. The favourable religious rulings and the resources available should enable transplantation to develop rapidly in the next few years in the Middle East and West Asia.

  12. Mineral facilities of Africa and the Middle East

    USGS Publications Warehouse

    Eros, J.M.; Candelario-Quintana, Luissette

    2006-01-01

    This map displays over 1,500 mineral facilities in Africa and the Middle East. The mineral facilities include mines, plants, mills, or refineries of aluminum, cement, coal, copper, diamond, gold, iron and steel, nickel, platinum-group metals, salt, and silver, among others. The data used in this poster were compiled from multiple sources, including the 2004 USGS Minerals Yearbook (Africa and Middle East volume), Minerals Statistics and Information from the USGS Web site (http://minerals.usgs.gov/minerals/), and data collected by USGS minerals information country specialists. Data reflect the most recent published table of industry structure for each country. Other sources include statistical publications of individual countries, annual reports and press releases of operating companies, and trade journals. Due to the sensitivity of some energy commodity data, the quality of these data should be evaluated on a country-by-country basis. Additional information and explanation is available from the country specialists. See Table 1 for general information about each mineral facility site including country, location and facility name, facility type, latitude, longitude, mineral commodity, mining method, main operating company, status, capacity, and units.

  13. Hepatitis B epidemiology in Asia, the Middle East and Africa.

    PubMed

    André, F

    2000-02-18

    Asia and Africa have previously been classified as areas of high endemicity for hepatitis B virus (HBV), but in some countries highly effective vaccination programmes have shifted this pattern towards intermediate or low endemicity. Thus, China is now the only country in Asia where HBV endemicity is high. Countries with intermediate endemicity include India, Korea, the Philippines, Taiwan and Thailand, and those with low endemicity include Japan, Pakistan, Bangladesh, Singapore, Sri Lanka and Malaysia. Most countries in Africa have high HBV endemicity, with the exceptions of Tunisia and Morocco, which have intermediate endemicity. Zambia has borderline intermediate/high endemicity. In the Middle East, Bahrain, Iran, Israel and Kuwait are areas of low endemicity, Cyprus, Iraq and the United Arab Emirates have intermediate endemicity, and Egypt, Jordan, Oman, Palestine, Yemen and Saudi Arabia have high endemicity. All of these Middle East countries reach a large proportion of their population with hepatitis B vaccination, which is reducing the infection rate, particularly in Saudi Arabia. The vaccination programme in Taiwan has also greatly reduced the HBV infection rate. Future vaccination programmes must take into account the mode of transmission of HBV, the healthcare infrastructure to deliver vaccination, and the socioeconomic and political factors in each individual country, to determine the most cost-effective way of infection control.

  14. Oil and gas development in Middle East in 1987

    SciTech Connect

    Hemer, D.O.; Gohrbandt, K.H.A.; Phillips, C.B.

    1988-10-01

    Petroleum production in Middle East countries during 1987 totaled an estimated 4,500,500,000 bbl (an average rate of 12,330,137 b/d), up slightly from the revised 1986 total of 4,478,972,000 bbl. Iran, Iraq, Syria, and Yemen Arab Republic had significant increases; Kuwait and Saudi Arabia had significant decreases. Production was established for the first time in People's Democratic Republic of Yemen. New fields went on production in Iraq, Oman, People's Democratic Republic of Yemen, and Syria, and significant oil discoveries were reported in Iraq, Oman, People's Democratic Republic of Yemen, Syria, and Yemen Arab Republic. The level of exploration increased in 1987 with new concessions awarded in some countries, drilling and seismic activities on the increase, new regions in mature areas explored for the first time, and significant reserve additions reported in new and old permits. The Iraq-Iran war still had a negative impact in some regions of the Middle East, particularly in and around the Gulf. 11 figs., 4 tabs.

  15. Broadband Lg Attenuation Modeling in the Middle East

    SciTech Connect

    Pasyanos, M E; Matzel, E M; Walter, W R; Rodgers, A J

    2008-08-21

    We present a broadband tomographic model of Lg attenuation in the Middle East derived from source- and site-corrected amplitudes. Absolute amplitude measurements are made on hand-selected and carefully windowed seismograms for tens of stations and thousands of crustal earthquakes resulting in excellent coverage of the region. A conjugate gradient method is used to tomographically invert the amplitude dataset of over 8000 paths over a 45{sup o} x 40{sup o} region of the Middle East. We solve for Q variation, as well as site and source terms, for a wide range of frequencies ranging from 0.5-10 Hz. We have modified the standard attenuation tomography technique to more explicitly define the earthquake source expression in terms of the seismic moment. This facilitates the use of the model to predict the expected amplitudes of new events, an important consideration for earthquake hazard or explosion monitoring applications. The attenuation results have a strong correlation to tectonics. Shields have low attenuation, while tectonic regions have high attenuation, with the highest attenuation at 1 Hz is found in eastern Turkey. The results also compare favorably to other studies in the region made using Lg propagation efficiency, Lg/Pg amplitude ratios and two-station methods. We tomographically invert the amplitude measurements for each frequency independently. In doing so, it appears the frequency-dependence of attenuation is not compatible with the power law representation of Q(f), an assumption that is often made.

  16. Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Kumar, Mia; Mazur, Steven; Ork, Britini L.; Postnikova, Elena; Hensley, Lisa E.; Jahrling, Peter B.; Johnson, Reed; Holbrook, Michael R.

    2015-01-01

    Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a recently emerged virus that has caused a number of human infections and deaths, primarily in the Middle East. The transmission of MERS-CoV to humans has been proposed to be as a result of contact with camels, but evidence of human-to-human transmission also exists. In order to work with MERS-CoV in a laboratory setting, the US Centers for Disease Control and Prevention (CDC) has determined that MERS-CoV should be handled at a biosafety level (BSL) 3 (BSL-3) biocontainment level. Many processes and procedures used to characterize MERS-CoV and to evaluate samples from MERS-CoV infected animals are more easily and efficiently completed at BSL-2 or lower containment. In order to complete experimental work at BSL-2, demonstration or proof of inactivation is required before removal of specimens from biocontainment laboratories. In the studies presented here, we evaluated typical means of inactivating viruses prior to handling specimens at a lower biocontainment level. We found that Trizol, AVL buffer and gamma irradiation were effective at inactivating MERS-CoV, that formaldehyde-based solutions required at least 30 minutes of contact time in a cell culture system while a mixture of methanol and acetone required 60 minutes to inactivate MERS-CoV. Together, these data provide a foundation for safely inactivating MERS-CoV, and potentially other coronaviruses, prior to removal from biocontainment facilities. PMID:26190637

  17. Aerosol optical depth trend over the Middle East

    NASA Astrophysics Data System (ADS)

    Klingmueller, Klaus; Pozzer, Andrea; Metzger, Swen; Abdelkader, Mohamed; Stenchikov, Georgiy; Lelieveld, Jos

    2016-04-01

    We use the combined Dark Target/Deep Blue aerosol optical depth (AOD) satellite product of the Moderate-resolution Imaging Spectroradiometer (MODIS) collection 6 to study trends over the Middle East between 2000 and 2015. Our analysis corroborates a previously identified positive AOD trend over large parts of the Middle East during the period 2001 to 2012. By relating the annual AOD to precipitation, soil moisture and surface wind, being the main factors controlling the dust cycle, we identify regions where these attributes are significantly correlated to the AOD over Saudi Arabia, Iraq and Iran. The Fertile Crescent turns out to be of prime importance for the AOD trend over these countries. Using multiple linear regression we show that AOD trend and interannual variability can be attributed to the above mentioned dust cycle parameters, confirming that the AOD increase is predominantly driven by dust. In particular, the positive AOD trend relates to a negative soil moisture trend. This suggests that increasing temperature and decreasing relative humidity in the last decade have promoted soil drying, leading to increased dust emissions and AOD; consequently an AOD increase is expected due to climate change. Based on simulations using the ECHAM/MESSy atmospheric chemistry-climate model (EMAC), we interpret the correlations identified in the observational data in terms of causal relationships.

  18. Inactivation and safety testing of Middle East Respiratory Syndrome Coronavirus.

    PubMed

    Kumar, Mia; Mazur, Steven; Ork, Britini L; Postnikova, Elena; Hensley, Lisa E; Jahrling, Peter B; Johnson, Reed; Holbrook, Michael R

    2015-10-01

    Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a recently emerged virus that has caused a number of human infections and deaths, primarily in the Middle East. The transmission of MERS-CoV to humans has been proposed to be as a result of contact with camels, but evidence of human-to-human transmission also exists. In order to work with MERS-CoV in a laboratory setting, the US Centers for Disease Control and Prevention (CDC) has determined that MERS-CoV should be handled at a biosafety level (BSL) 3 (BSL-3) biocontainment level. Many processes and procedures used to characterize MERS-CoV and to evaluate samples from MERS-CoV infected animals are more easily and efficiently completed at BSL-2 or lower containment. In order to complete experimental work at BSL-2, demonstration or proof of inactivation is required before removal of specimens from biocontainment laboratories. In the studies presented here, we evaluated typical means of inactivating viruses prior to handling specimens at a lower biocontainment level. We found that Trizol, AVL buffer and gamma irradiation were effective at inactivating MERS-CoV, that formaldehyde-based solutions required at least 30 min of contact time in a cell culture system while a mixture of methanol and acetone required 60 min to inactivate MERS-CoV. Together, these data provide a foundation for safely inactivating MERS-CoV, and potentially other coronaviruses, prior to removal from biocontainment facilities. PMID:26190637

  19. Diasporic dreaming: return reproductive tourism to the Middle East.

    PubMed

    Inhorn, Marcia C

    2011-11-01

    This article attempts to capture the dynamics of return reproductive tourism to the Middle East, based on ethnographic research undertaken at four different Middle Eastern locales (Egypt, Lebanon, United Arab Emirates and Arab America). Across the Middle Eastern diaspora, which is now vast, due to the disruptions of war and political violence, infertile couples often dream of making a test-tube baby 'back home' for a variety of cultural, moral and psychological reasons. These reasons – including medical expatriotism, the language of medicine, co-religion and moral trustworthiness, donor phenotype, the comforts of home and discrimination – are rarely highlighted in the scholarly literature on cross-border reproductive care. Thus, further empirical investigation is needed in order to assess additional reasons for reproductive travel beyond Euro-America. Of particular concern are the needs of 'stranded' refugee populations, who are constrained from seeking assisted reproduction technology 'back home', but who may face economic constraints and cultural discrimination in host communities. PMID:21955490

  20. Contaminant profiles for surface water, sediment, flora and fauna associated with the mangrove fringe along middle and lower East Tampa Bay

    EPA Science Inventory

    Contaminant concentrations are reported for surface water, sediment, seagrass, mangroves, Florida Crown conch, blue crabs and fish collected during 2010-2011 from the mangrove fringe along eastern Tampa Bay. Concentrations of trace metals, chlorinated pesticides, atrazine, total ...

  1. Biochemical Characterization of Middle East Respiratory Syndrome Coronavirus Helicase

    PubMed Central

    Lazarus, Hilary

    2016-01-01

    ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) helicase is a superfamily 1 helicase containing seven conserved motifs. We have cloned, expressed, and purified a Strep-fused recombinant MERS-CoV nonstructural protein 13 (M-nsp13) helicase. Characterization of its biochemical properties showed that it unwound DNA and RNA similarly to severe acute respiratory syndrome CoV nsp13 (S-nsp13) helicase. We showed that M-nsp13 unwound in a 5′-to-3′ direction and efficiently unwound the partially duplex RNA substrates with a long loading strand relative to those of the RNA substrates with a short or no loading strand. Moreover, the Km of ATP for M-nsp13 is inversely proportional to the length of the 5′ loading strand of the partially duplex RNA substrates. Finally, we also showed that the rate of unwinding (ku) of M-nsp13 is directly proportional to the length of the 5′ loading strand of the partially duplex RNA substrate. These results provide insights that enhance our understanding of the biochemical properties of M-nsp13. IMPORTANCE Coronaviruses are known to cause a wide range of diseases in humans and animals. Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans in the Middle East, Europe, North Africa, and the United States of America. Helicases are motor proteins that catalyze the processive separation of double-stranded nucleic acids into two single-stranded nucleic acids by utilizing the energy derived from ATP hydrolysis. MERS-CoV helicase is one of the most important viral replication enzymes of this coronavirus. Herein, we report the first bacterial expression, enzyme purification, and biochemical characterization of MERS-CoV helicase. The knowledge obtained from this study might be used to identify an inhibitor of MERS-CoV replication, and the helicase might be used as a therapeutic target.

  2. Biochemical Characterization of Middle East Respiratory Syndrome Coronavirus Helicase

    PubMed Central

    Lazarus, Hilary

    2016-01-01

    ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) helicase is a superfamily 1 helicase containing seven conserved motifs. We have cloned, expressed, and purified a Strep-fused recombinant MERS-CoV nonstructural protein 13 (M-nsp13) helicase. Characterization of its biochemical properties showed that it unwound DNA and RNA similarly to severe acute respiratory syndrome CoV nsp13 (S-nsp13) helicase. We showed that M-nsp13 unwound in a 5′-to-3′ direction and efficiently unwound the partially duplex RNA substrates with a long loading strand relative to those of the RNA substrates with a short or no loading strand. Moreover, the Km of ATP for M-nsp13 is inversely proportional to the length of the 5′ loading strand of the partially duplex RNA substrates. Finally, we also showed that the rate of unwinding (ku) of M-nsp13 is directly proportional to the length of the 5′ loading strand of the partially duplex RNA substrate. These results provide insights that enhance our understanding of the biochemical properties of M-nsp13. IMPORTANCE Coronaviruses are known to cause a wide range of diseases in humans and animals. Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans in the Middle East, Europe, North Africa, and the United States of America. Helicases are motor proteins that catalyze the processive separation of double-stranded nucleic acids into two single-stranded nucleic acids by utilizing the energy derived from ATP hydrolysis. MERS-CoV helicase is one of the most important viral replication enzymes of this coronavirus. Herein, we report the first bacterial expression, enzyme purification, and biochemical characterization of MERS-CoV helicase. The knowledge obtained from this study might be used to identify an inhibitor of MERS-CoV replication, and the helicase might be used as a therapeutic target. PMID:27631026

  3. Biochemical Characterization of Middle East Respiratory Syndrome Coronavirus Helicase.

    PubMed

    Adedeji, Adeyemi O; Lazarus, Hilary

    2016-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) helicase is a superfamily 1 helicase containing seven conserved motifs. We have cloned, expressed, and purified a Strep-fused recombinant MERS-CoV nonstructural protein 13 (M-nsp13) helicase. Characterization of its biochemical properties showed that it unwound DNA and RNA similarly to severe acute respiratory syndrome CoV nsp13 (S-nsp13) helicase. We showed that M-nsp13 unwound in a 5'-to-3' direction and efficiently unwound the partially duplex RNA substrates with a long loading strand relative to those of the RNA substrates with a short or no loading strand. Moreover, the Km of ATP for M-nsp13 is inversely proportional to the length of the 5' loading strand of the partially duplex RNA substrates. Finally, we also showed that the rate of unwinding (ku) of M-nsp13 is directly proportional to the length of the 5' loading strand of the partially duplex RNA substrate. These results provide insights that enhance our understanding of the biochemical properties of M-nsp13. IMPORTANCE Coronaviruses are known to cause a wide range of diseases in humans and animals. Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans in the Middle East, Europe, North Africa, and the United States of America. Helicases are motor proteins that catalyze the processive separation of double-stranded nucleic acids into two single-stranded nucleic acids by utilizing the energy derived from ATP hydrolysis. MERS-CoV helicase is one of the most important viral replication enzymes of this coronavirus. Herein, we report the first bacterial expression, enzyme purification, and biochemical characterization of MERS-CoV helicase. The knowledge obtained from this study might be used to identify an inhibitor of MERS-CoV replication, and the helicase might be used as a therapeutic target. PMID:27631026

  4. Game theory, international law, and future environmental cooperation in the Middle East

    SciTech Connect

    Hirsch, M.

    1998-12-31

    Through the use of game theory, this article explores some of the principal factors influencing the emergence and maintenance of international cooperation in order to develop legal guidelines for establishing an effective environmental mechanism in the Middle East. As this article shows, game theory concepts and models provide a valuable tool for analyzing the phenomenon of cooperation, enabling international lawyers to shape legal norms which will enhance the prospects for environmental cooperation in the Middle East. Part 2 of this article sets for the basic concepts and models of game theory and its relationship to modern international relations theory. Part 3 presents a game theoretical analysis of two major environmental settings in the Middle East: marine pollution in the Gulf of Aqaba and water contamination of the Mountain Aquifer. It then suggests some legal mechanisms to enhance the likelihood of cooperation in these settings. Part 4 concludes the article by exploring the options nd limits of combining game theory and international law as an instrument to improve the prospects of cooperation. The article ultimately states that this combination offers scholars and policy-makers important insights into better legal mechanisms for long-term international cooperation.

  5. CRUSTAL TECTONICS AND SEISMICITY OF THE MIDDLE EAST

    NASA Astrophysics Data System (ADS)

    Ghalib, H. A.; Gritto, R.; Sibol, M. S.; Herrmann, R. B.; Aleqabi, G. I.; Caron, P. F.; Wagner, R. A.; Ali, B. S.; Ali, A. A.

    2009-12-01

    The Arabian plate describes a geological entity and a dynamic system that has been in continuous interaction with the African plate to the west and south and the Eurasian plate to the north and east. The western and southern boundaries are distinguished by see floor spreading along the Gulf of Aden and Red Sea and transform faulting along the Dead Sea, whereas the northern and eastern boundaries are portrayed by compressional suture zones under thrusting the Turkish and Iranian plateaus. Despite this favorable juxtaposition of continental land masses and the plethora of national seismic networks in every country of the Middle East, the majority of published research on the Arabian plate and surrounding tectonic blocks still depends primarily on global seismographic stations and occasional local networks. Since 2005, we deployed a number of seismic stations, and more recently a five elements array, in close proximity to the northeastern boundary of the Arabian plate. The primary objective of the effort is to better understand the regional seismicity and seismotectonics of the Arabian plate and surrounding regions. To date over a terabyte of high quality 100 sps continuous three-component broadband data have been collected and being analyzed to derive models representative of the greater Middle East tectonic setting. This goal is, in part, achieved by estimating local and regional seismic velocity models using receiver function and surface wave dispersion analyses, and by using these models to obtain accurate hypocenter locations and event focal mechanisms. The resulting events distribution reveals a distinct picture of the interaction between the seismicity and tectonics of the region. The highest seismicity rate seems to be confined to the active northern section of the Zagros thrust zone, while it decreases towards the southern end, before the intensity increases again in the Bandar Abbas region. Spatial distribution of the events and stations provide thorough

  6. Stillbirth During Infection With Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Payne, Daniel C.; Iblan, Ibrahim; Alqasrawi, Sultan; Al Nsour, Mohannad; Rha, Brian; Tohme, Rania A.; Abedi, Glen R.; Farag, Noha H.; Haddadin, Aktham; Sanhouri, Tarek Al; Jarour, Najwa; Swerdlow, David L.; Jamieson, Denise J.; Pallansch, Mark A.; Haynes, Lia M.; Gerber, Susan I.; Al Abdallat, Mohammad Mousa

    2015-01-01

    We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing. PMID:24474813

  7. Middle East respiratory syndrome (MERS): a new zoonotic viral pneumonia.

    PubMed

    Cunha, Cheston B; Opal, Steven M

    2014-08-15

    Coronaviruses have traditionally been associated with mild upper respiratory tract infections throughout the world. In the fall of 2002, a new coronavirus emerged in in Asia causing severe viral pneumonia, i.e., severe acute respiratory syndrome (SARS). Nearly a decade following the SARS epidemic, a new coronavirus causing severe viral pneumonia has emerged, i.e., middle east respiratory syndrome (MERS). Since the initial case of MERS-CoV occurred in June of 2012 in Saudi Arabia there have been 688 confirmed cases and 282 deaths in 20 countries. Although both SARS and MERS are caused by coronaviruses, SARS was characterized by efficient human transmission and relatively low mortality rate. In contrast, MERS is relatively inefficiently transmitted to humans but has a high mortality rate. Given the potential overlap in presentation and manifestation, it is important to understand the clinical and epidemiologic differences between MERS, SARS and influenza.

  8. Stillbirth during infection with Middle East respiratory syndrome coronavirus.

    PubMed

    Payne, Daniel C; Iblan, Ibrahim; Alqasrawi, Sultan; Al Nsour, Mohannad; Rha, Brian; Tohme, Rania A; Abedi, Glen R; Farag, Noha H; Haddadin, Aktham; Al Sanhouri, Tarek; Jarour, Najwa; Swerdlow, David L; Jamieson, Denise J; Pallansch, Mark A; Haynes, Lia M; Gerber, Susan I; Al Abdallat, Mohammad Mousa

    2014-06-15

    We conducted an epidemiologic investigation among survivors of an outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in Jordan. A second-trimester stillbirth occurred during the course of an acute respiratory illness that was attributed to MERS-CoV on the basis of exposure history and positive results of MERS-CoV serologic testing. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy-related data, including biological specimens for confirmatory testing. PMID:24474813

  9. Middle East respiratory syndrome coronavirus: epidemiology and disease control measures

    PubMed Central

    Al-Tawfiq, Jaffar A; Memish, Ziad A

    2014-01-01

    The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in 2012 resulted in an increased concern of the spread of the infection globally. MERS-CoV infection had previously caused multiple health-care-associated outbreaks and resulted in transmission of the virus within families. Community onset MERS-CoV cases continue to occur. Dromedary camels are currently the most likely animal to be linked to human MERS-CoV cases. Serologic tests showed significant infection in adult camels compared to juvenile camels. The control of MERS-CoV infection relies on prompt identification of cases within health care facilities, with institutions applying appropriate infection control measures. In addition, determining the exact route of transmission from camels to humans would further add to the control measures of MERS-CoV infection. PMID:25395865

  10. Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus.

    PubMed

    Uyeki, Timothy M; Erlandson, Karl J; Korch, George; O'Hara, Michael; Wathen, Michael; Hu-Primmer, Jean; Hojvat, Sally; Stemmy, Erik J; Donabedian, Armen

    2016-07-01

    Preclinical development of and research on potential Middle East respiratory syndrome coronavirus (MERS-CoV) medical countermeasures remain preliminary; advancements are needed before most countermeasures are ready to be tested in human clinical trials. Research priorities include standardization of animal models and virus stocks for studying disease pathogenesis and efficacy of medical countermeasures; development of MERS-CoV diagnostics; improved access to nonhuman primates to support preclinical research; studies to better understand and control MERS-CoV disease, including vaccination studies in camels; and development of a standardized clinical trial protocol. Partnering with clinical trial networks in affected countries to evaluate safety and efficacy of investigational therapeutics will strengthen efforts to identify successful medical countermeasures. PMID:27191188

  11. Development of Medical Countermeasures to Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Erlandson, Karl J.; Korch, George; O’Hara, Michael; Wathen, Michael; Hu-Primmer, Jean; Hojvat, Sally; Stemmy, Erik J.; Donabedian, Armen

    2016-01-01

    Preclinical development of and research on potential Middle East respiratory syndrome coronavirus (MERS-CoV) medical countermeasures remain preliminary; advancements are needed before most countermeasures are ready to be tested in human clinical trials. Research priorities include standardization of animal models and virus stocks for studying disease pathogenesis and efficacy of medical countermeasures; development of MERS-CoV diagnostics; improved access to nonhuman primates to support preclinical research; studies to better understand and control MERS-CoV disease, including vaccination studies in camels; and development of a standardized clinical trial protocol. Partnering with clinical trial networks in affected countries to evaluate safety and efficacy of investigational therapeutics will strengthen efforts to identify successful medical countermeasures. PMID:27191188

  12. Trafficking and contract migrant workers in the Middle East.

    PubMed

    Jureidini, Ray

    2010-01-01

    The paper addresses a number of issues regarding the extent to which trafficking may be applied to migrant domestic workers who enter under the kafala system of sponsorship in the Middle East. Migrant domestic workers are the most numerous of those mentioned in reports on trafficking for labour exploitation in the region. The discussion seeks to determine whether "trafficking" can be ex post facto, rather than ex ante? In other words, can the label of trafficking be attributed only after the worker has arrived in the receiving country and is victimized according to the principles of trafficking protocols? In addition, must there be a proven intent to traffic by agents, or can employers who harm and/or exploit them be considered as traffickers alone? Should the harm done to workers on arrival at their place of work be classified (and assisted) as victims of trafficking, or as exploited workers?

  13. Middle East respiratory syndrome: obstacles and prospects for vaccine development

    PubMed Central

    Papaneri, Amy B.; Johnson, Reed F.; Wada, Jiro; Bollinger, Laura; Jahrling, Peter B.; Kuhn, Jens H.

    2016-01-01

    Summary The recent emergence of Middle East respiratory syndrome (MERS) highlights the need to engineer new methods for expediting vaccine development against emerging diseases. However, several obstacles prevent pursuit of a licensable MERS vaccine. First, the lack of a suitable animal model for MERS complicates in vivo testing of candidate vaccines. Second, due to the low number of MERS cases, pharmaceutical companies have little incentive to pursue MERS vaccine production as the costs of clinical trials are high. In addition, the timeline from bench research to approved vaccine use is 10 years or longer. Using novel methods and cost-saving strategies, genetically engineered vaccines can be produced quickly and cost-effectively. Along with progress in MERS animal model development, these obstacles can be circumvented or at least mitigated. PMID:25864502

  14. Astronomy in the Middle East and North Africa

    NASA Astrophysics Data System (ADS)

    Athem Alsabti, Abdul

    2015-08-01

    Recent turbulent events in the Middle East and North Africa have influenced all aspects of life. Education in general, including astronomy, teaching and research has all been greatly affected. In this presentation, the current situation regarding astronomy in this region is reviewed in detail. This is based on visits made to Tunisia and Algeria recently on behalf of the IAU and other visits to Iraq, Qatar, Egypt and Jordan in recent years, as well as on discussions and communications with astronomers, officials and astronomical and educational institutes in the region. Discussions have also been established with astronomers from Iran, Oman and Morocco. Ideas and proposals will be presented on the best ways for the IAU and the international academic community to help under these circumstances.

  15. High altitude wind resource in the Middle East

    NASA Astrophysics Data System (ADS)

    Yip, Chak Man Andrew; Gunturu, Udaya B.; Stenchikov, Georgiy L.

    2016-04-01

    This study presents a first identification of areas favorable to Airborne Wind Energy (AWE) Systems deployment in the Middle East and illustrates their diurnal and seasonal characteristics. Optimal heights of AWE system deployment are computed. The AWE literature has conventionally used a top-down approach where AWE potentials are estimated as a fraction of wind power density. This study takes the bottom-up approach where the regional AWE potentials are estimated using realistic machine specification with assumptions upon deployment conditions. The annual energy production per capita illustrates the potential of AWE systems in fulfilling electricity needs at the current level for several countries in the region. Our estimate also compares favorably to the near-surface wind power potential using identical data source from a previous study. In addition, the non-monotonicity in the vertical profile is examined for areas with potential LLJ influences, where behaviors in wind speed and direction similar to that of inertial oscillations are identified.

  16. Aeroallergens, atopy and allergic rhinitis in the Middle East.

    PubMed

    Goronfolah, L

    2016-01-01

    The literature on the nature and prevalence of indoor and/or outdoor aeroallergens, atopy and symptoms of rhinitis and asthma in the Middle East region (defined here as Bahrain, Egypt, Iran, Iraq, Israel, Jordan, Kuwait, Lebanon, Oman, Palestine, Qatar, Kingdom of Saudi Arabia - KSA, Syria, United Arab Emirates and Yemen) was reviewed. Although documentation was poor in all countries other than Iran and the KSA, a wide range of "global" and "local" aeroallergens (grass, weed and tree pollens, fungal spores, insect allergens, dander, and house dust mites) has been observed across the region. The prevalence of current self-reported or parent-reported symptoms of rhinitis ranged from 9% to 38%. Researchers have suggested that the high atopy rates and self-reported rhinitis rates are associated with an on-going shift towards a "western" lifestyle.

  17. Aerosol optical depth trend over the Middle East

    NASA Astrophysics Data System (ADS)

    Klingmüller, Klaus; Pozzer, Andrea; Metzger, Swen; Stenchikov, Georgiy L.; Lelieveld, Jos

    2016-04-01

    We use the combined Dark Target/Deep Blue aerosol optical depth (AOD) satellite product of the moderate-resolution imaging spectroradiometer (MODIS) collection 6 to study trends over the Middle East between 2000 and 2015. Our analysis corroborates a previously identified positive AOD trend over large parts of the Middle East during the period 2001 to 2012. We relate the annual AOD to precipitation, soil moisture and surface winds to identify regions where these attributes are directly related to the AOD over Saudi Arabia, Iraq and Iran. Regarding precipitation and soil moisture, a relatively small area in and surrounding Iraq turns out to be of prime importance for the AOD over these countries. Regarding surface wind speed, the African Red Sea coastal area is relevant for the Saudi Arabian AOD. Using multiple linear regression we show that AOD trends and interannual variability can be attributed to soil moisture, precipitation and surface winds, being the main factors controlling the dust cycle. Our results confirm the dust driven AOD trends and variability, supported by a decreasing MODIS-derived Ångström exponent and a decreasing AERONET-derived fine mode fraction that accompany the AOD increase over Saudi Arabia. The positive AOD trend relates to a negative soil moisture trend. As a lower soil moisture translates into enhanced dust emissions, it is not needed to assume growing anthropogenic aerosol and aerosol precursor emissions to explain the observations. Instead, our results suggest that increasing temperature and decreasing relative humidity in the last decade have promoted soil drying, leading to increased dust emissions and AOD; consequently an AOD increase is expected due to climate change.

  18. American School Textbooks: How They Portrayed the Middle East from 1898 to 1994

    ERIC Educational Resources Information Center

    Morgan, Hani

    2008-01-01

    The portrayal of the Middle East in school textbooks has been reported to be inaccurate and negative as late as the mid 1990's. Numerous major studies conducted by various researchers and organizations indicate that school textbooks written between the 1970's and 1990's contributed to existing stereotypes of the Middle East held by many Americans.…

  19. Leaders of American Universities in the Middle East Bring Their Message to the U.S.

    ERIC Educational Resources Information Center

    Chronicle of Higher Education, 2007

    2007-01-01

    Last week the leaders of four American universities in the Middle East visited Washington and New York to present a simple message: Don't forget about us. "The American public is seeing nothing but bad-news stories coming out of the Middle East," said David D. Arnold, president of the American University in Cairo, who met with editors of The…

  20. A Dialog of Faith: Reflections on Middle East Conflict from Jewish, Muslim and Christian Perspectives

    ERIC Educational Resources Information Center

    Stover, William James

    2005-01-01

    In 2004, Santa Clara University's Bannan Center for Jesuit Education brought together online religious teachers and practitioners from the three world religions to discuss important issues associated with Middle East conflict: resistance, suicide bombing, America's role in the Middle East, and the future shape of peace. These conversations aimed…

  1. Exportations of Symptomatic Cases of MERS-CoV Infection to Countries outside the Middle East

    PubMed Central

    O’Hagan, Justin J.; Jewett, Amy; Gambhir, Manoj; Cohen, Nicole J.; Haber, Yoni; Pesik, Nicki; Swerdlow, David L.

    2016-01-01

    In 2012, an outbreak of infection with Middle East respiratory syndrome coronavirus (MERS-CoV), was detected in the Arabian Peninsula. Modeling can produce estimates of the expected annual number of symptomatic cases of MERS-CoV infection exported and the likelihood of exportation from source countries in the Middle East to countries outside the region. PMID:27358972

  2. Recurring middle Pleistocene outburst floods in east-central Alaska

    USGS Publications Warehouse

    Froese, D.G.; Smith, D.G.; Westgate, J.A.; Ager, T.A.; Preece, S.J.; Sandhu, A.; Enkin, R.J.; Weber, F.

    2003-01-01

    Recurring glacial outburst floods from the Yukon-Tanana Upland are inferred from sediments exposed along the Yukon River near the mouth of Charley River in east-central Alaska. Deposits range from imbricate gravel and granules indicating flow locally extending up the Yukon valley, to more distal sediments consisting of at least 10 couplets of planar sands, granules, and climbing ripples with up-valley paleocurrent indicators overlain by massive silt. An interglacial organic silt, occurring within the sequence, indicates at least two flood events are associated with an earlier glaciation, and at least three flood events are associated with a later glaciation which postdates the organic silt. A minimum age for the floods is provided by a glass fission track age of 560,000 ?? 80,000 yr on the GI tephra, which occurs 8 m above the flood beds. A maximum age of 780,000 yr for the floods is based on normal magnetic polarity of the sediments. These age constraints allow us to correlate the flood events to the early-middle Pleistocene. And further, the outburst floods indicate extensive glaciation of the Yukon-Tanana Upland during the early-middle Pleistocene, likely representing the most extensive Pleistocene glaciation of the area. ?? 2003 University of Washington. Published by Elsevier Inc. All rights reserved.

  3. LLNL Middle East and North Africa research database

    SciTech Connect

    Dodge, D; Hauk, T; Moore, R M; O'Boyle, J; Ruppert, S

    1999-07-23

    The Lawrence Livermore National Laboratory (LLNL) Comprehensive Nuclear-Test-Ban Treaty Research and Development (CTBT R and D) program has made significant progress populating a comprehensive seismic research database (RDB) for seismic events and derived research products in the Middle East and North Africa (MENA). Our original ME/NA study region has enlarged and is now defined as an area including the Middle East, Africa, Europe, Southwest Asia, the Former Soviet Union and the Scandinavian/Arctic region. The LLNL RDB will facilitate calibration of all International Monitoring System (IMS) stations (primary and auxiliary) or their surrogates (if not yet installed) as well as a variety of gamma stations. The RDB provides not only a coherent framework in which to store and organize large volumes of collected seismic waveforms and associated event parameter information, but also provides an efficient data processing/research environment for deriving location and discrimination correction sur faces and capabilities. In order to accommodate large volumes of data from many sources with diverse formats the RDB is designed to be flexible and extensible in addition to maintaining detailed quality control information and associated metadata. Station parameters, instrument responses, phase pick information, and event bulletins were compiled and made available through the RDB. For seismic events in the MENA region occurring between 1976 and 1999, we have systematically assembled, quality checked and organized event waveforms; continuous seismic data from 1990 to present are archived for many stations. Currently, over 11,400 seismic events and 1.2 million waveforms are maintained in the RDB and made readily available to researchers. In addition to open sources of seismic data, we have established collaborative relationships with several ME/NA countries that have yielded additional ground truth and broadband waveform data essential for regional calibration and capability

  4. Synoptic analysis of dust storms in the Middle East

    NASA Astrophysics Data System (ADS)

    Hamidi, Mehdi; Kavianpour, Mohammad Reza; Shao, Yaping

    2013-05-01

    Dust storm in the Middle East and south-west Asia is a natural hazard and the Tigris-Euphrates alluvial plain has been recognized as the main dust source in this area. In this study, more than 60 dust storms that occurred during the period 2003-2011 are investigated on the basis of MODIS satellite images, and 12 of the dust storms are selected for synoptic analysis using the NCEP-NCAR Reanalysis Data. The potential dust sources in the Middle East and south-west Asian region (20°E to 80°E, 5°N to 50°N) are analyzed and used in the synoptic analysis. Dust storms in the region can be grouped into two main categories, i.e., the Shamal dust storms and the frontal dust storms. Synoptic systems, associated with the two categories, are distinguished and the frequency of the patterns is identified. For 68% of the Shamal dust storms, a high pressure system is situated between 0°E to 30°E and 27°N to 45°N, and a low pressure system between 50°E to 70°E and 23°N to 43°N. For 86% of the frontal dust storms, a high is located between 51°E to 67°E and 18°N to 33°N and a low between 28°E to 48°E and 32°N to 43°N. Three main patterns for Shamal dust storms are identified, which represent about 60% of the Shamal dust storms. This analysis confirms that the Shamal is related to the anticyclones located over northern Africa to Eastern Europe and the monsoon trough over Iraq, southern Iran, Pakistan and the Indian Subcontinent. The analysis also shows that the main dust sink for the frontal dust storms in Tigris and Euphrates alluvial plain extends from center of Iraq to west and center of Iran and, in most severe cases, to northern Iran and the southern coast of the Caspian Sea.

  5. Enhancing Middle East climate change monitoring and indexes

    SciTech Connect

    Sensoy, S.; Peterson, T.C.; Zhang, X.

    2007-08-15

    Extreme climate events can have significant impacts on both natural and human systems, and therefore it is important to know if and how climate extremes are changing. Analysis of extremes requires long-term daily station data and, unfortunately, there are many regions in the world where these data are not internationally exchanged. The Intergovernmental Panel on Climate Change (IPCC) Third Assessment Report (Folland et al. 2001) relied heavily on the multinational analysis of Frich et al (2002). However, Frich et al. had no results from all of Central and South America, and most of Africa and southern Asia, including the Middle East. To remedy this situation for the IPCC Fourth Assessment Report, the joint World Meteorological Organization Commission for Climatology/World Climate Research Programme (WCRP) project on Climate Variability and Predictability (CLIVAR) Expert Team on Climate Change Detection, Monitoring, and Indices (Zwiers et al. 2003) internationally coordinated a series of five regional climate change workshops and a set of indices for analyses of extremes. Two workshops covered the Americas, one in Brazil and one in Guatemala. One workshop addressed southern Africa. A workshop in India involved south and central Asia, while the workshop for the Middle East sought to address the region from Turkey to Iran and from Georgia to the southern tip of the Arabian Peninsula. The key to a successful workshop is a collaborative approach between outside experts and regional participants. The participants here broght long-term daily precipitation and maximum and minimum temperature data, station history information, an understanding of their country's climate, and a willingness to analyze thse data under the tutelage of outside experts. The outside experts brought knowledge of the crucial data and climate change issues, presentations to explain these issues, and user-friendly software to aid the analyses. Xuebin Zhang of Environment Canada wrote the workshop

  6. Nuclear Explosion Monitoring Research and Development in the Middle East

    NASA Astrophysics Data System (ADS)

    Pasyanos, M. E.; Walter, W. R.; Myers, S. C.; Matzel, E.; Gok, R.; Simmons, N. A.; Ford, S. R.; Rodgers, A. J.; Ruppert, S.; Hauk, T. F.; Dodge, D.; Ganzberger, M.; Ramirez, A. L.; Ryall, F.

    2010-12-01

    Lawrence Livermore National Laboratory has a long-standing research and development program for nuclear explosion monitoring. Here, we cover aspects of recent work applied to the Middle East region, specifically data management, seismic location, event identification, and magnitude estimation. Seismic data from broadband stations in the region is available through a combination of expanding global networks, improved and increasingly available national networks, and temporary deployments. Managing the huge amounts of data necessary to perform the work is an underappreciated aspect of monitoring research. Our research database provides vertically-integrated management of seismic data, catalogs, picks, magnitudes, etc., as well as analysis tools that are fully integrated into the database. Seismic locations have improved significantly through a succession of models starting with empirical corrections to 1-D models, progressing through to 2 1/2 -D models which significantly improve regional body-wave travel times by characterizing the upper mantle as a gradient, and on through high-resolution fully 3-D models that are currently in development. Our surface wave tomography results provide additional constraints on Earth lithospheric structure and can be used to improve Ms determination. Event identification has been achieved through a number of methods including the traditional mb:Ms discriminant, regional high-frequency P/S discriminants, and analysis of the complete moment tensor solution, which also has the possibility of distinguishing between explosions and mining-type events. Optimal use of these methods requires calibration, such as the multi-phase attenuation model of the crust and upper mantle that has been developed for the region. Use of the models reduces scatter of the earthquake population and reduces misclassification. Another important aspect of explosion monitoring is getting robust estimates of event magnitude, and hence explosive yield. This has been

  7. 76 FR 30152 - East Calloway County Middle School Mercury Spill Site, Murray, Calloway County, KY; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... AGENCY East Calloway County Middle School Mercury Spill Site, Murray, Calloway County, KY; Notice of... response costs concerning the East Calloway County Middle School Mercury Spill Site located in Murray... Site name East Calloway County ] Middle School Mercury Spill Site by one of the following methods:...

  8. Is the Saudi public aware of Middle East respiratory syndrome?

    PubMed

    Al-Mohrej, Omar A; Al-Shirian, Sarah D; Al-Otaibi, Salman K; Tamim, Hani M; Masuadi, Emad M; Fakhoury, Hana M

    2016-01-01

    To limit the spread of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia, the Ministry of Health tried to raise public awareness using different public campaigns. We aimed to measure public awareness of MERS in Saudi Arabia. A cross-sectional study was conducted between May and June 2014 using a newly designed Arabic questionnaire that was distributed and completed online. We analyzed the response of 1149 respondents across Saudi Arabia. We found that 97% of the participants were aware of MERS. In addition, 72% realized that coughing and sneezing could spread the infection. Furthermore, 83% thought that some patients with MERS could be cured. Moreover, 62% knew that no vaccine can prevent the disease. However, only 36% realized that taking antibiotics will not stop the infection, and only 41% recognized that no medication has yet been manufactured to treat it. Regarding protection measures, 74% used hand sanitizers, 43% avoided crowded places, and 11% wore masks in public places. Moreover, only 47% knew that bats and camels are the primary source of the virus. As anticipated, this level of awareness varied between the different categories of the studied population. Female, married, older, and more educated participants were significantly more knowledgeable about the disease. Public awareness of MERS is generally sufficient. However, some false beliefs about treatment were fairly common. In addition, almost half of the population remains unaware that bats and camels are the most likely sources of the virus. PMID:26589657

  9. Collaborative Intervention of Middle East Respiratory Syndrome: Rapid Response Team.

    PubMed

    Lee, Jacob; Kim, Woo Joo

    2016-06-01

    On May 20th 2015, a 68 year old man was the first to be diagnosed with Middle East Respiratory Syndrome-Corona Virus (MERS-CoV) in Korea. He travelled to Bahrain, Saudi Arabia, and Qatar for 16 days. On May 4th 2015, the patient entered Korea, with febrile sense and respiratory symptoms that appeared on May 11th. The MERS-CoV Outbreak became worse and several patients had to be admitted throughout various hospitals starting at the beginning of June. This situation led to a nationwide chaos. The Rapid Response Team (RRT) was organized after the Korean government's calling for specialists that were composed of 15 Infectious disease Doctors and 2 Infection Control professionals on the 8th of June 2015. The main purpose of the RRT were: 1) consultation to the Government controlling MERS-CoV outbreak. 2) Visit hospitals that were exposed to MERS-CoV infected patients, and to provide advice regarding infection control strategy for rehabilitating of the exposed hospitals. Since June 8th, the RRT visited more than 10 hospitals and an effective consultation was carried out. Most of the hospitals were recovering from the MERS outbreak since early July. Cooperation between the government and private sector experts was very effective. The efforts of government and private sector experts overcame the initial chaos situation. It could prevent further deterioration of the MERS outbreak.

  10. Collaborative Intervention of Middle East Respiratory Syndrome: Rapid Response Team

    PubMed Central

    2016-01-01

    On May 20th 2015, a 68 year old man was the first to be diagnosed with Middle East Respiratory Syndrome-Corona Virus (MERS-CoV) in Korea. He travelled to Bahrain, Saudi Arabia, and Qatar for 16 days. On May 4th 2015, the patient entered Korea, with febrile sense and respiratory symptoms that appeared on May 11th. The MERS-CoV Outbreak became worse and several patients had to be admitted throughout various hospitals starting at the beginning of June. This situation led to a nationwide chaos. The Rapid Response Team (RRT) was organized after the Korean government's calling for specialists that were composed of 15 Infectious disease Doctors and 2 Infection Control professionals on the 8th of June 2015. The main purpose of the RRT were: 1) consultation to the Government controlling MERS-CoV outbreak. 2) Visit hospitals that were exposed to MERS-CoV infected patients, and to provide advice regarding infection control strategy for rehabilitating of the exposed hospitals. Since June 8th, the RRT visited more than 10 hospitals and an effective consultation was carried out. Most of the hospitals were recovering from the MERS outbreak since early July. Cooperation between the government and private sector experts was very effective. The efforts of government and private sector experts overcame the initial chaos situation. It could prevent further deterioration of the MERS outbreak. PMID:27433376

  11. LLNL Middle East and North Africa research database

    SciTech Connect

    Ruppert, S.D.; Hauk, T.F.; Leach, R.

    1997-07-15

    The Lawrence Livermore National Laboratory (LLNL) CTBT R{ampersand}D program has made significant progress assembling a comprehensive seismic database (DB) for events and derived parameters in the Middle East and North Africa (ME/NA). The LLNL research DB provides not only a coherent framework in which store and organize large volumes of collected seismic waveforms and associated event parameter information but also provides an efficient data processing/research environment. The DB is designed to be flexible and extensible in order to accommodate the large volumes of data in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Researchers can make use of the relational nature of the DB and interactive analysis tools to quickly and efficiently process large volumes of data. Seismic waveforms have been systematically collected form a wide range of local and regional networks using numerous earthquake bulletins and converted a common format based on CSS3.O while undergoing quality control and corrections of errors. By combining traveltime observations, event characterization studies, and regional wave-propagation studies of the LLNL CTBT team, we are assembling a library of ground truth information and event location correction surfaces required to support the ME/NA regionalization program. Corrections and parameters distilled from the LLNL research DB will provide needed contributions to the DOE knowledge base for the ME/NA region and enable the USNDC and IDC to effectively verify CTBT compliance.

  12. Paleointensity determinations from Middle Miocene volcanic rocks, Far East, Russia

    NASA Astrophysics Data System (ADS)

    Shcherbakov, Valeriy; Shcherbakova, Valentina; Zhidkov, Grigoriy; Bretstein, Yury

    2010-05-01

    Paleomagnetic and paleointensity studies of a representative collection of Middle Miocene volcanic rocks of (12.4-10.0) Ma age from Far East, Russia were carried out. A comprehensive rock magnetic investigation has been performed in order to determine the mineralogy of magnetic fraction and to identify the origin of NRM. Successful Thellier palaeointensity determinations with pTRM checks were obtained for 4 sites (33 samples). The Thellier experiments were complimented by the Wilson's express method. Values of the VDMs range from 3.1 to 7.5 (10^22 Am^2) with the mean VDM = 5.5×10^22 Am^2. A total 88 Thellier-type palaeointensity determinations were found in the World Paleointensity database for the 5-23 Ma period with the overall mean VDM = 5×10^22 Am^2. The VDM distribution is characterized by high variance from 1.5 to 12 (10^22 Am^2). No significant difference between the VDM distributions for the normal and reverse polarity intervals was revealed.

  13. Collaborative Intervention of Middle East Respiratory Syndrome: Rapid Response Team.

    PubMed

    Lee, Jacob; Kim, Woo Joo

    2016-06-01

    On May 20th 2015, a 68 year old man was the first to be diagnosed with Middle East Respiratory Syndrome-Corona Virus (MERS-CoV) in Korea. He travelled to Bahrain, Saudi Arabia, and Qatar for 16 days. On May 4th 2015, the patient entered Korea, with febrile sense and respiratory symptoms that appeared on May 11th. The MERS-CoV Outbreak became worse and several patients had to be admitted throughout various hospitals starting at the beginning of June. This situation led to a nationwide chaos. The Rapid Response Team (RRT) was organized after the Korean government's calling for specialists that were composed of 15 Infectious disease Doctors and 2 Infection Control professionals on the 8th of June 2015. The main purpose of the RRT were: 1) consultation to the Government controlling MERS-CoV outbreak. 2) Visit hospitals that were exposed to MERS-CoV infected patients, and to provide advice regarding infection control strategy for rehabilitating of the exposed hospitals. Since June 8th, the RRT visited more than 10 hospitals and an effective consultation was carried out. Most of the hospitals were recovering from the MERS outbreak since early July. Cooperation between the government and private sector experts was very effective. The efforts of government and private sector experts overcame the initial chaos situation. It could prevent further deterioration of the MERS outbreak. PMID:27433376

  14. Middle East respiratory syndrome coronavirus infection is inhibited by griffithsin.

    PubMed

    Millet, Jean K; Séron, Karin; Labitt, Rachael N; Danneels, Adeline; Palmer, Kenneth E; Whittaker, Gary R; Dubuisson, Jean; Belouzard, Sandrine

    2016-09-01

    Highly pathogenic human coronaviruses associated with a severe respiratory syndrome, including Middle East respiratory syndrome coronavirus (MERS-CoV), have recently emerged. The MERS-CoV epidemic started in 2012 and is still ongoing, with a mortality rate of approximately 35%. No vaccine is available against MERS-CoV and therapeutic options for MERS-CoV infections are limited to palliative and supportive care. A search for specific antiviral treatments is urgently needed. Coronaviruses are enveloped viruses, with the spike proteins present on their surface responsible for virus entry into the target cell. Lectins are attractive anti-coronavirus candidates because of the highly glycosylated nature of the spike protein. We tested the antiviral effect of griffithsin (GRFT), a lectin isolated from the red marine alga Griffithsia sp. against MERS-CoV infection. Our results demonstrate that while displaying no significant cytotoxicity, griffithsin is a potent inhibitor of MERS-CoV infection. Griffithsin also inhibits entry into host cells of particles pseudotyped with the MERS-CoV spike protein, suggesting that griffithsin inhibits spike protein function during entry. Spike proteins have a dual function during entry, they mediate binding to the host cell surface and also the fusion of the viral envelope with host cell membrane. Time course experiments show that griffithsin inhibits MERS-CoV infection at the binding step. In conclusion, we identify griffithsin as a potent inhibitor of MERS-CoV infection at the entry step. PMID:27424494

  15. Fibrous calcite from the Middle Ordovician Holston Formation (east Tennessee)

    SciTech Connect

    Tobin, K.J.; Walker, K.R. . Dept. of Geological Sciences)

    1993-03-01

    Fibrous calcite from buildups, which occur near the top of the Middle Ordovician Holston Formation, were examined from two localities near Knoxville, TN (Alcoa Highway and Deanne Quarry). Buildups at these localities were deposited under open-marine conditions, slightly down-slope from the platform edge. Fibrous calcite (mainly radiaxial fibrous) occur most commonly as cements in mainly stromatactis structures present in bioherms and intergranular porosity in beds that flank bioherms. Fibrous calcite is interpreted to have been precipitated in a marine setting. Fibrous calcite is uniformly turbid or banded with interlayered turbid and clearer cement. Fibrous calcite most commonly shows patchy or blotchy dull-non-luminescence under cathodoluminescence. Bands of uniformly non-luminescent and relatively bright luminescent calcite are present. [delta][sup 13]C compositions of fibrous calcite vary little (0.6 to 1.0%) but [delta][sup 18]O values are highly variable ([minus]4.8 to [minus]7.1%). Post-marine cement consists of ferroan and non-ferroan, dull luminescent equant calcite ([delta][sup 13]C = 0.3 to 0.8; [delta][sup 18]O = [minus]8.6 to [minus]11.5) and is interpreted as precipitated in a deep meteoric or burial setting. Depleted [delta][sup 18]O compositions of fibrous calcite reflect addition of post-depositional calcite during stabilization. Most enriched [delta][sup 13]C and [delta][sup 18]O fibrous calcite composition are similar to enriched values from other Middle Ordovician southern Appalachian buildups (other localities of Holston (TN) and Effna (VA) formations) ([delta][sup 13]C = 0.3 to 0.8; [delta][sup 18]O = [minus]3.9 to [minus]4.8) and may reflect fibrous calcite precipitated in isotopic equilibrium with Middle Ordovician sea water.

  16. Current Status of Nuclear Medicine Practice in the Middle East.

    PubMed

    Paez, Diana; Becic, Tarik; Bhonsle, Uday; Jalilian, Amir R; Nuñez-Miller, Rodolfo; Osso, Joao Alberto

    2016-07-01

    The practice of nuclear medicine (NM) in the Middle East region has experienced an important growth in the last 2 decades and has become crucial in providing healthcare to the region's population of about 395 million people. Even though there are some countries in which the services provided are limited to basic coverage of studies with (99m)Tc and (131)I, most have well-established practices covering most of the available studies in this medical specialty; this is the case in for example, Iran, Israel, Kuwait, Saudi Arabia, and Turkey. According to data provided by the NM professionals in the 17 countries included in the present publication, which was collected by the International Atomic Energy Agency in 2015, the total number of gamma cameras in the region is 910 with an average of 2.3 gamma cameras per million inhabitants. Out of these, 107 cameras, or 12%, are SPECT/CT cameras. There are 194 operating PET/CT scanners, translating to one PET/CT scanner for 2.04 million people on average. The availability of PET/CT scanners in relation to population is the highest in Lebanon and Kuwait, with 2.2 and 1.7 scanners per million people, respectively. There is a total of 628 NM centers in the 17 countries, whereas most NM centers belong to the public healthcare system and in most of the countries are widely spread and not confined exclusively to capital cities. As for the radionuclide therapies, (131)I is used regularly in diagnostic workup as well as in therapeutic applications in all the countries included in this analysis. Only five countries have the capability of assembling (99)Mo-(99m)Tc generators (Egypt, Iran, Saudi Arabia, Israel, and Turkey), and cold kits are produced in several countries. Although there are no capabilities in the region to produce (99)Mo from nuclear reactors, a total of 46 cyclotrons are operated for production of PET radionuclides. The most widely used PET tracer in the region is (18)F-FDG followed by (18)F-NaF; concomitantly, the

  17. Current Status of Nuclear Medicine Practice in the Middle East.

    PubMed

    Paez, Diana; Becic, Tarik; Bhonsle, Uday; Jalilian, Amir R; Nuñez-Miller, Rodolfo; Osso, Joao Alberto

    2016-07-01

    The practice of nuclear medicine (NM) in the Middle East region has experienced an important growth in the last 2 decades and has become crucial in providing healthcare to the region's population of about 395 million people. Even though there are some countries in which the services provided are limited to basic coverage of studies with (99m)Tc and (131)I, most have well-established practices covering most of the available studies in this medical specialty; this is the case in for example, Iran, Israel, Kuwait, Saudi Arabia, and Turkey. According to data provided by the NM professionals in the 17 countries included in the present publication, which was collected by the International Atomic Energy Agency in 2015, the total number of gamma cameras in the region is 910 with an average of 2.3 gamma cameras per million inhabitants. Out of these, 107 cameras, or 12%, are SPECT/CT cameras. There are 194 operating PET/CT scanners, translating to one PET/CT scanner for 2.04 million people on average. The availability of PET/CT scanners in relation to population is the highest in Lebanon and Kuwait, with 2.2 and 1.7 scanners per million people, respectively. There is a total of 628 NM centers in the 17 countries, whereas most NM centers belong to the public healthcare system and in most of the countries are widely spread and not confined exclusively to capital cities. As for the radionuclide therapies, (131)I is used regularly in diagnostic workup as well as in therapeutic applications in all the countries included in this analysis. Only five countries have the capability of assembling (99)Mo-(99m)Tc generators (Egypt, Iran, Saudi Arabia, Israel, and Turkey), and cold kits are produced in several countries. Although there are no capabilities in the region to produce (99)Mo from nuclear reactors, a total of 46 cyclotrons are operated for production of PET radionuclides. The most widely used PET tracer in the region is (18)F-FDG followed by (18)F-NaF; concomitantly, the

  18. Reinvestigating Three Paleo Lake Records in the Middle East using new Model Results

    NASA Astrophysics Data System (ADS)

    Reuter, J. M.; Stott, L. D.; Buenning, N. H.; Yoshimura, K.

    2013-12-01

    Here we present a reinterpretation of three oxygen isotope records from three Middle Eastern Lakes (Zeribar, Van and Eski Acigo). These lake isotope records were interpreted previously to document changes in the precipitation-to-evaporation ratio (Eski and Van) and varying seasonality of precipitation over the lake (Zeribar). These differing interpretations are a consequence of inadequate constraints on atmospheric dynamics that influence isotopic variability in the water cycle of the Middle East. We present new isotope-enabled atmospheric model results that provide a more comprehensive view of each of the potential influences that affected these lake records. Currently the Middle East exhibits a highly seasonal precipitation cycle with the bulk of the rainfall occurring during the winter months. The yearly isotopic composition of rainfall exhibits a seasonal cycle as well with decreased values during the winter and higher isotopic values in both fall and spring. We conducted two model simulations with the Isotope-incorporated Global Spectral Model (IsoGSM): 1) with present-day conditions and 2) with mid-Holocene conditions. For the mid-Holocene simulations changes were made to the surface forcing, orbital parameters and greenhouse gas concentrations. These results show that the annual averaged oxygen isotopes in precipitation 6000 years ago were depleted on the order of 1 to 3‰ compared to present day. The model results are consistent with the published lake core records. However, the shift in isotopic composition of precipitation results from the combined influences of orbital changes, the changes in green house gases and surface forcings. We have evaluated the relative contribution of each of the forcings and present a re-interpretation of the Middle Eastern lake records.

  19. The state of mobile health in the developing world and the Middle East.

    PubMed

    Ababtain, Arwa F; Almulhim, Deana A; Househ, Mowafa S

    2013-01-01

    The rapid expansion and development of mobile technology have advanced an area called mobile health (mHealth), which is expected to improve healthcare delivery and increase the efficacy of healthcare services. This paper provides an overview of mHealthuse in the developing world with a specific focus on the Middle East. Different search engines and databases were used to search for Mobile Health (mHealth) literature on the developing world and the Middle East, in September 2012. The results show that there is a growing demand within the developing world and the Middle East for the use of mobile technologies that focus on information gathering and sharing, accessibility and reach, and public health. The future of mHealth in the developing world and the Middle East is also discussed.

  20. 75 FR 15686 - Middle East Public Health Mission; Application Deadline Extended

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Middle East Public Health Mission; Application Deadline Extended AGENCY... Applications Mission recruitment will be conducted in an open and public manner, including publication in...

  1. 75 FR 18783 - Middle East Public Health Mission; Application Deadline Extended

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration Middle East Public Health Mission; Application Deadline Extended AGENCY... Applications Mission recruitment will be conducted in an open and public manner, including publication in...

  2. The Islamic Middle East: A Short Annotated Bibliography for High School Teachers and Libraries

    ERIC Educational Resources Information Center

    Birnbaum, E.; And Others

    1977-01-01

    An annotated bibliography of 133 books about the Middle East. Categories are reference works; general works; pre-modern history and geography; Islamic religion, law, institutions, and thought; Islamic literature; and Islamic art and archaeology. (AV)

  3. EAST ELEVATION, TOWER, MIDDLE LEFT. Glass plate stereopair number PA1430139 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EAST ELEVATION, TOWER, MIDDLE LEFT. Glass plate stereopair number PA-1430-139 LC-HABS-GS05-ET-3 157.4630. Left (printed) - Independence Hall Complex, Independence Hall, 500 Chestnut Street, Philadelphia, Philadelphia County, PA

  4. EAST ELEVATION, TOWER, MIDDLE RIGHT. Glass plate stereopair number PA1430139 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EAST ELEVATION, TOWER, MIDDLE RIGHT. Glass plate stereopair number PA-1430-139 LC-HABS-GS05-ET-4 157.4631. Left (printed) - Independence Hall Complex, Independence Hall, 500 Chestnut Street, Philadelphia, Philadelphia County, PA

  5. EAST ELEVATION, TOWER, MIDDLE RIGHT. Glass plate stereopair number PA1430139 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EAST ELEVATION, TOWER, MIDDLE RIGHT. Glass plate stereopair number PA-1430-139 LC-HABS-GS05-ET-4 157.4631. Right (not printed) - Independence Hall Complex, Independence Hall, 500 Chestnut Street, Philadelphia, Philadelphia County, PA

  6. EAST ELEVATION, TOWER, MIDDLE LEFT. Glass plate stereopair number PA1430139 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EAST ELEVATION, TOWER, MIDDLE LEFT. Glass plate stereopair number PA-1430-139 LC-HABS-GS05-ET-3 157.4630. Right (not printed) - Independence Hall Complex, Independence Hall, 500 Chestnut Street, Philadelphia, Philadelphia County, PA

  7. Hypovitaminosis D in the Middle East and North Africa

    PubMed Central

    Bassil, Darina; Rahme, Maya; Hoteit, Maha; Fuleihan, Ghada El-Hajj

    2013-01-01

    Background: The Middle East and North Africa (MENA) region registers some of the highest rates of hypovitaminosis D worldwide.   Aim: We systematically reviewed the prevalence of hypovitaminosis D, rickets and osteomalacia, their predictors and impact on major outcomes, in the region. Methods: Medline, Pubmed and Embase search engines, entering keywords and concepts, combined with individual countries of interest, were used. Search was limited years 2000–2012; and review articles were used for the period preceding year 2000. Results: Rickets and osteomalacia still occur in this sunny region. Hypovitaminosis D prevails, with rates varying 30–90%, considering a desirable serum 25 hydroxy-vitamin D [25(OH)D] of 20 ng/ml. Advancing age, female gender, multi-parity, clothing style, season, socio-economic status and urban living are recognized predictors of hypovitaminosis D in adults. Prolonged breastfeeding without vitamin D supplementation and low dietary calcium intake are the recognized risk factors for rickets and hypovitaminosis D in children.. Associations with pain score and disease activity in rheumatologic disorders, viral load and interleukins in hepatitis C, BMI, lipids and insulin sensitivity, blood pressure, heart failure and mortality are described. Sun exposure in adults decreased prevalence of metabolic syndrome in one study. Few randomized vitamin D trials revealed that the majority of mothers or children failed to achieve a desirable 25(OH)D level, even with doses by far exceeding current recommendations. A trial in adolescent girls reveals substantial bone and lean mass increments. Conclusion: Hypovitaminosis D is prevalent in MENA. The lack of populations based studies, gaps in studies in infants, pre-pubertal children and pregnant women, hinder the development of region specific guidelines and constitute a major obstacle to impact this chronic and most often subclinical disease. PMID:24194968

  8. Drivers for animal welfare policies in the Middle East.

    PubMed

    Aidaros, H

    2014-04-01

    Religion, ethics and culture are an important group of drivers for animal welfare policies in the Middle East. In many countries of the region the understanding of animal welfare is expressed more in terms of religious precepts and humane ethics than via regulations and legislation. In fact, regulatory and legislated animal welfare standards are still not well implemented and many animal welfare issues require attention. The Qur'an provides considerable support for conscientiously attending to animal welfare. For example, the Islamic rules on the process of slaughter were intended to provide a quick, humane and relatively painless death. Current practices that are not in accordance with these religious teachings may cause great suffering to animals. Although these rules have been in place for 1,400 years or more, now, in the 21st Century, they are found to closely correspond to the related standards of the World Organisation for Animal Health (OIE). The OIE plays an important role in improving animal welfare by developing global animal welfare standards. These should assist countries in two important ways: first, by helping them to establish new, or to refine existing, animal welfare legislation, and second, at the OIE regional level, by facilitating interactions between Member Countries as they develop and refine a strategic plan for the advancement of animal welfare. As the OIE standards are compatible with the requirements of Islamic law, issuing animal welfare legislation referring to those standards and implementing them at a national level is highly recommended. A dialogue between the OIE and the Veterinary Services and religious leaders in the region should therefore start with the objective of improving animal welfare.

  9. Animal models of Middle East Respiratory Syndrome coronavirus infection

    PubMed Central

    van Doremalen, Neeltje; Munster, Vincent J.

    2015-01-01

    The emergence of the Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second time that a new, highly pathogenic coronavirus has emerged in the human population in the 21st century. In this review, we discuss the current state of knowledge of animal models of MERS-CoV infection. Commonly used laboratory animal species such as Syrian hamsters, mice and ferrets are not susceptible to MERS-CoV, due to differences in the MERS-CoV receptor dipeptyl peptidase 4 (DPP4). The initially developed animal models comprise two nonhuman primate species, the rhesus macaque and the common marmoset. Rhesus macaques develop a mild to moderate respiratory disease upon inoculation, reminiscent of milder MERS cases, whereas marmosets develop a moderate to severe respiratory disease, recapitulating the severe disease observed in some patients. Dromedary camels, considered to be the reservoir for MERS-CoV, develop a mild upper respiratory tract infection with abundant viral shedding. Although normal mice are not susceptible to MERS-CoV, expression of the human DPP4 (hDPP4) overcomes the lack of susceptibility. Transgenic hDPP4 mice develop severe and lethal respiratory disease upon inoculation with MERS-CoV. These hDPP4 transgenic mice are potentially the ideal first line animal model for efficacy testing of therapeutic and prophylactic countermeasures. Further characterization of identified countermeasures would ideally be performed in the common marmoset model, due to the more severe disease outcome. This article forms part of a symposium in Antiviral Research on “From SARS to MERS: research on highly pathogenic human coronaviruses.” PMID:26192750

  10. Genomics and zoonotic infections: Middle East respiratory syndrome.

    PubMed

    Wernery, U; Lau, S K P; Woo, P C Y

    2016-04-01

    The emergence of Middle East respiratory syndrome (MERS) and the discovery of MERS coronavirus (MERS-CoV) in 2012 suggests that another SARS-like epidemic is occurring. Unlike the severe acute respiratory syndrome (SARS) epidemic, which rapidly disappeared in less than one year, MERS has persisted for over three years. More than 1,600 cases of MERS have been reported worldwide, and the disease carries a worryingly high fatality rate of >30%. A total of 182 MERS-CoV genomes have been sequenced, including 94 from humans and 88 from dromedary camels. The 182 genomes all share >99% identity, indicating minimal variation among MERS-CoV genomes. MERS-CoV is a lineage C Betacoronavirus (ßCoV). MERS-CoV genomes can be roughly divided into two clades: clade A, which contains only a few strains, and clade B, to which most strains belong. In contrast to ORF1ab and structural proteins, the putative proteins encoded by ORF3, ORF4a, ORF4b, ORF5 and ORF8b in the MERS-CoV genome do not share homology with any known host or virus protein, other than those of its closely related lineage C ßCoVs. Human and dromedary viral genomes have intermingled, indicating that multiple camel-to-human transmission events have occurred. The multiple origins of MERS-CoV suggest that the virus has been resident in dromedaries for many years. This is consistent with the detection of anti-MERS-CoV antibodies in dromedary camels as early as the 1980s. PMID:27217178

  11. Genomics and zoonotic infections: Middle East respiratory syndrome.

    PubMed

    Wernery, U; Lau, S K P; Woo, P C Y

    2016-04-01

    The emergence of Middle East respiratory syndrome (MERS) and the discovery of MERS coronavirus (MERS-CoV) in 2012 suggests that another SARS-like epidemic is occurring. Unlike the severe acute respiratory syndrome (SARS) epidemic, which rapidly disappeared in less than one year, MERS has persisted for over three years. More than 1,600 cases of MERS have been reported worldwide, and the disease carries a worryingly high fatality rate of >30%. A total of 182 MERS-CoV genomes have been sequenced, including 94 from humans and 88 from dromedary camels. The 182 genomes all share >99% identity, indicating minimal variation among MERS-CoV genomes. MERS-CoV is a lineage C Betacoronavirus (ßCoV). MERS-CoV genomes can be roughly divided into two clades: clade A, which contains only a few strains, and clade B, to which most strains belong. In contrast to ORF1ab and structural proteins, the putative proteins encoded by ORF3, ORF4a, ORF4b, ORF5 and ORF8b in the MERS-CoV genome do not share homology with any known host or virus protein, other than those of its closely related lineage C ßCoVs. Human and dromedary viral genomes have intermingled, indicating that multiple camel-to-human transmission events have occurred. The multiple origins of MERS-CoV suggest that the virus has been resident in dromedaries for many years. This is consistent with the detection of anti-MERS-CoV antibodies in dromedary camels as early as the 1980s.

  12. Drivers for animal welfare policies in the Middle East.

    PubMed

    Aidaros, H

    2014-04-01

    Religion, ethics and culture are an important group of drivers for animal welfare policies in the Middle East. In many countries of the region the understanding of animal welfare is expressed more in terms of religious precepts and humane ethics than via regulations and legislation. In fact, regulatory and legislated animal welfare standards are still not well implemented and many animal welfare issues require attention. The Qur'an provides considerable support for conscientiously attending to animal welfare. For example, the Islamic rules on the process of slaughter were intended to provide a quick, humane and relatively painless death. Current practices that are not in accordance with these religious teachings may cause great suffering to animals. Although these rules have been in place for 1,400 years or more, now, in the 21st Century, they are found to closely correspond to the related standards of the World Organisation for Animal Health (OIE). The OIE plays an important role in improving animal welfare by developing global animal welfare standards. These should assist countries in two important ways: first, by helping them to establish new, or to refine existing, animal welfare legislation, and second, at the OIE regional level, by facilitating interactions between Member Countries as they develop and refine a strategic plan for the advancement of animal welfare. As the OIE standards are compatible with the requirements of Islamic law, issuing animal welfare legislation referring to those standards and implementing them at a national level is highly recommended. A dialogue between the OIE and the Veterinary Services and religious leaders in the region should therefore start with the objective of improving animal welfare. PMID:25000780

  13. Filipino workers in the Middle East: social profile and policy implications.

    PubMed

    Smart, J E; Teodosio, V A; Jimenez, C J

    1985-03-01

    The characteristics of international labor migrants from the Philippines are examined. "Based on an analysis of a sample of 495 Middle East workers and 1983 worker placements, this paper presents a profile of Filipino workers in the Middle East with reference to such variables as occupation, gender, age and work experience, civil status, education, Philippine residence, household size and number of dependents." (summary in FRE, SPA)

  14. Water Budget of East Maui, Hawaii

    USGS Publications Warehouse

    Shade, Patricia J.

    1999-01-01

    Ground-water recharge is estimated from six monthly water budgets calculated using long-term average rainfall and streamflow data, estimated pan-evaporation and fog-drip data, and soil characteristics. The water-budget components are defined seasonally, through the use of monthly data, and spatially by broad climatic and geohydrologic areas, through the use of a geographic information system model. The long-term average water budget for east Maui was estimated for natural land-use conditions. The average rainfall, fog-drip, runoff, evapotranspiration, and ground-water recharge volumes for the east Maui study area are 2,246 Mgal/d, 323 Mgal/d, 771 Mgal/d, 735 Mgal/d, and 1,064 Mgal/d, respectively.

  15. Impacts of The Future Changes in Extreme Events on Migration in The Middle East

    NASA Astrophysics Data System (ADS)

    An, Nazan; Turp, M. Tufan; Ozturk, Tugba; Kurnaz, M. Levent

    2016-04-01

    Natural hazards are defined as extreme events that threat people, their homes and their neighborhoods. They damage housing, food production system and other infrastructures. The frequency of natural hazards namely drought, floods can influence the residential decision-making and can cause substantial residential mobility by affecting relatively greater numbers of people in the region. Developing countries are more vulnerable to the impacts of natural hazards. Therefore, environmental migration can be associated with natural hazards especially in the developing countries. Limited water resources and demographic dynamics of the Middle East make the region one of the most affected domains from the impacts of natural hazards. In this study, we consider the relationship between migration as a demographic process and the frequency of natural hazards in the Middle East for the period of 2020 - 2045 with respect to 1980 - 2005 by performing the projection according to the scenario of IPCC, namely RCP8.5 through the RegCM4.4 and combining them with an econometric analysis. This research has been supported by Boǧaziçi University Research Fund Grant Number 10421.

  16. Cardiovascular Risk Factor Burden in Africa and the Middle East: The Africa Middle East Cardiovascular Epidemiological (ACE) Study

    PubMed Central

    Alsheikh-Ali, Alawi A.; Omar, Mohamed I.; Raal, Frederick J.; Rashed, Wafa; Hamoui, Omar; Kane, Abdoul; Alami, Mohamed; Abreu, Paula; Mashhoud, Walid M.

    2014-01-01

    Background Increased urbanization in the developing world parallels a rising burden of chronic diseases. Developing countries account for ∼80% of global cardiovascular (CV) deaths, but contribute a paucity of systematic epidemiological data on CV risk factors. Objective To estimate the prevalence of CV risk factors in rural and urban cohorts attending general practice clinics in the Africa and Middle East (AfME) region. Methods In a cross-sectional epidemiological study, the presence of CV risk factors (hypertension, diabetes mellitus (diabetes), dyslipidemia, obesity, smoking and abdominal obesity) were evaluated in stable adult outpatients attending general practice primary care clinics. A rural population was defined as isolated (>50 km or lack of easy access to commuter transportation) from urban centers. Results 4,378 outpatients were systematically recruited from 94 clinics across 14 AfME countries. Mean age was 46±14 years and 52% of outpatients were female. A high prevalence of dyslipidemia (70%) and abdominal obesity (68%) were observed, followed by hypertension (43%) and diabetes (25%). The vast majority of outpatients (92%) had at least one modifiable CV risk factor, many (74%) had more than one, and half (53%) had 3 or more. These findings were observed in both genders and across urban and rural centers. Among outpatients with pre-existing hypertension or dyslipidemia, many were not at their target blood pressure or LDL-cholesterol goals. Conclusion Cardiovascular risk factors are highly prevalent among relatively young, stable outpatients attending general practice clinics across AfME. The findings support opportunistic screening for CV risk factors whenever outpatients visit a general practitioner and provide an opportunity for early identification and management of CV risk factors, including lifestyle interventions. PMID:25090638

  17. Disillusionment with Higher Education in the Middle East and the United States

    ERIC Educational Resources Information Center

    Cochran, Judith A.

    2011-01-01

    University graduates in the Middle East and the United States of America are disillusioned with their higher education degrees. Youth expect to be well employed upon graduation and to improve their social status. Employment has been guaranteed from the earliest university certificates granted in Middle Eastern yeshivas, Houses of Learning, and…

  18. Teaching East Asia in Middle Schools: Lesson Plans Contributed at the 1998 East Asian Studies Center Summer Workshop.

    ERIC Educational Resources Information Center

    Indiana Univ., Bloomington. East Asian Studies Center.

    This document contains five middle school lesson plans that teach about East Asia, focusing on Japan, China, and Korea. Lessons deal with geography, history, cultural comparisons, and trade relations. Lesson plans include background information, materials needed, extension and enrichment ideas, a lesson script, a rubric, a list of resources, and…

  19. Crustal Structure of the Middle East from Regional Seismic Studies

    NASA Astrophysics Data System (ADS)

    Gritto, Roland; Sibol, Matthew; Caron, Pierre; Ghalib, Hafidh; Chen, Youlin

    2010-05-01

    We present results of crustal studies obtained with seismic data from the Northern Iraq Seismic Network (NISN). NISN has operated ten broadband stations in north-eastern Iraq since late 2005. This network was supplemented by the five-element broadband Iraq Seismic Array (KSIRS) in 2007. More recently, the former Iraq Seismic Network (ISN), destroyed during the war with Iran, was reestablished with the deployment of six broadband stations throughout Iraq. The aim of the present study is to derive models of the local and regional crustal structure of the Middle East, including Eastern Turkey, Iraq and Iran. To achieve this goal, we derive crustal velocity models using receiver function, surface wave and body wave analyses. These refined velocity models will eventually be used to obtain accurate hypocenter locations and event focal mechanisms. Our analysis of preliminary hypocenter locations produced a clearer picture of the seismicity associated with the tectonics of the region. The largest seismicity rate is confined to the active northern section of the Zagros thrust zone, while it decreases towards the southern end, before the intensity increases in the Bandar Abbas region again. Additionally, the rift zones in the Red Sea and the Gulf of Aden are clearly demarked by high seismicity rates. Surface wave velocity analysis resulted in a clear demarcation of the tectonic features in the region. The Arabian shield, Zagros thrust zone and the Red Sea are apparent through distinct velocity distributions separating them from each other. Furthermore, the shear wave velocity of the crust in North Iraq appears to be 10% higher than that of the Iranian plateau. The velocity anomaly of the Zagros mountains appears to be present into the upper mantle beyond the resolving limit of our model. Analysis of waveform data for obstructed pathways indicates clear propagation paths from the west or south-west across the Arabian shield as well as from the north and east into NISN. Phases

  20. LLNL Middle East, North Africa and Western Eurasia Knowledge Base

    SciTech Connect

    O'Boyle, J; Ruppert, S D; Hauk, T F; Dodge, D A; Ryall, F; Firpo, M A

    2001-07-12

    The Lawrence Livermore National Laboratory (LLNL) Ground-Based Nuclear Event Monitoring (GNEM) program has made significant progress populating a comprehensive Seismic Research Knowledge Base (SRKB) and deriving calibration parameters for the Middle East, North Africa and Western Eurasia (ME/NA/WE) regions. The LLNL SRKB provides not only a coherent framework in which to store and organize very large volumes of collected seismic waveforms, associated event parameter information, and spatial contextual data, but also provides an efficient data processing/research environment for deriving location and discrimination correction surfaces. The SRKB is a flexible and extensible framework consisting of a relational database (RDB), Geographical Information System (GIS), and associated product/data visualization and data management tools. This SRKB framework is designed to accommodate large volumes of data (almost 3 million waveforms from 57,000 events) in diverse formats from many sources (both LLNL derived research and integrated contractor products), in addition to maintaining detailed quality control and metadata. We have developed expanded look-up tables for critical station parameter information (including location and response) and an integrated and reconciled event catalog data set (including specification of preferred origin solutions and associated phase arrivals) for the PDE, CMT, ISC, REB and selected regional catalogs. Using the SRKB framework, we are combining traveltime observations, event characterization studies, and regional tectonic models to assemble a library of ground truth information and phenomenology (e.g. travel-time and amplitude) correction surfaces required for support of the ME/NA/WE regionalization program. We also use the SRKB to integrate data and research products from a variety of sources, such as contractors and universities, to merge and maintain quality control of the data sets. Corrections and parameters distilled from the LLNL SRKB

  1. Sustainable wastewater management for small communities in the Middle East and North Africa.

    PubMed

    Bakir, H A

    2001-04-01

    Accelerated expansion of wastewater services to small communities in the Middle East and North Africa (MENA) is essential in order to address serious concerns over water scarcity and pollution in addition to meeting the demand for convenience and protecting public health. Centralized and conventional wastewater systems are currently the preferred choice of planners and decision-makers in MENA. Water and funding are not available to provide these centralized conventional services to small communities. This paper presents an integrated approach to sustainable wastewater management for small communities in MENA under the severe water resources crisis. The approach calls for a paradigm shift from centralized conventional wastewater systems to decentralized wastewater systems. Management of wastewater in MENA should start at home. Wastewater generation should be reduced through a combination of domestic water conservation measures. On-site systems must be improved and monitored to control pollution and to recover water for non-potable water uses. Should the circumstances not allow the use of on-site systems, wastewater should be transported and managed through a community system applying the principles of decentralized wastewater management and using the settled sewers for wastewater transportation where appropriate. This approach will facilitate the accelerated and sustainable extension of environmentally responsible wastewater services to MENA's small communities. It offers great potential for cost reduction, accommodates the necessary domestic water conservation efforts, reduces freshwater inputs in wastewater transportation thus eliminating unnecessary demand on freshwater, reduces associated environmental risks and increases wastewater reuse opportunities.

  2. Evaluation ofthe Middle East and North Africa Land Data Assimilation System

    NASA Technical Reports Server (NTRS)

    Bolten, John D.; Rodell, Matthew; Zaitchik, Benjamin; Ozdogan, Mutlu; Anderson, Martha; Bergaoui, Karim B.; Khalaf, Adla J.; McDonnell, Rachael A.

    2012-01-01

    The Middle East and North Africa (MENA) region is dominated by dry, warm deserts, areas of dense population, and inefficient use of fresh water resources. Due to the scarcity, high intensity, and short duration of rainfall in the MENA, the region is prone to hydro climatic extremes that are realized by devastating floods and times of drought. However, given its widespread water stress and the considerable demand for water, the MENA remains relatively poorly monitored. This is due in part to the shortage of meteorological observations and the lack of data sharing between nations. As a result, the accurate monitoring of the dynamics of the water cycle in the MENA is difficult. The Land Data Assimilation System for the MENA region (MENA LDAS) has been developed to provide regional, gridded fields of hydrological states and fluxes relevant for water resources assessments. As an extension of the Global Land Data Assimilation System (GLDAS), the MENA LDAS was designed to aid in the identification and evaluation of regional hydrological anomalies by synergistically combining the physically-based Catchment Land Surface Model (CLSM) with observations from several independent data products including soil-water storage variations from the Gravity Recovery and Climate Experiment (GRACE) and irrigation intensity derived from the Moderate Resolution Imaging Spectroradiometer (MODIS). In this fashion, we estimate the mean and seasonal cycle of the water budget components across the MENA.

  3. Food habits and infant feeding in newly resettled refugee families from Chile and the Middle East.

    PubMed

    Hjern, A; Kocturk-Runefors, T; Jeppson, O

    1990-09-01

    Food habits and infant feeding patterns of 45 newly resettled refugee families from Chile and the Middle East were studied in the suburbs of Stockholm. The social background of the sample was mixed and the level of maternal education high with the exception of the rural Kurds from Turkey. Children from rural Middle East areas had been breastfed for longer periods than the children from urban areas. Solid and semi-solid foods were introduced late in the Middle East. Chileans had a characteristic meal pattern, emphasizing lunch and often replacing dinner with a light meal. Resettled Chileans and Middle Easterners had a varied and well balanced diet with the characteristics of each culture. Foods containing sucrose were consumed frequently in both refugee groups.

  4. Teaching about the Middle East: Challenges and Resource

    ERIC Educational Resources Information Center

    Jaffee, Cyrisse

    2004-01-01

    Barbara Petzen began working as a part-time outreach coordinator at Harvard University's Center for Middle Eastern Studies (CMES) a week before September 11, 2001. She was finishing her dissertation in Middle Eastern studies, specializing in the Ottoman Empire and Arab history, and thought it would be a good job to have while she completed her…

  5. The Future of Area Studies: The Middle East.

    ERIC Educational Resources Information Center

    Winder, R. B.

    1985-01-01

    Describes problems in Middle Eastern studies, focusing on: (1) the problem of access for students and faculty conducting research due to countries being completely closed or highly restrictive; (2) declines in Middle Eastern and American corporate donations to language and area studies as oil prices decrease; and (3) the difficulties inherent in…

  6. Recharge rates and aquifer hydraulic characteristics for selected drainage basins in middle and east Tennessee

    USGS Publications Warehouse

    Hoos, A.B.

    1990-01-01

    Quantitative information concerning aquifer hydrologic and hydraulic characteristics is needed to manage the development of ground-water resources. These characteristics are poorly defined for the bedrock aquifers in Middle and East Tennessee where demand for water is increasing. This report presents estimates of recharge rate, storage coefficient, diffusivity, and transmissivity for representative drainage basins in Middle and East Tennessee, as determined from analyses of stream-aquifer interactions. The drainage basins have been grouped according to the underlying major aquifer, then statistical descriptions applied to each group, in order to define area1 distribution of these characteristics. Aquifer recharge rates are estimated for representative low, average, and high flow years for 63 drainage basins using hydrograph analysis techniques. Net annual recharge during average flow years for all basins ranges from 4.1 to 16.8 in/yr (inches per year), with a mean value of 7.3 in. In general, recharge rates are highest for basins underlain by the Blue Ridge aquifer (mean value11.7 in/yr) and lowest for basins underlain by the Central Basin aquifer (mean value 5.6 in/yr). Mean recharge values for the Cumberland Plateau, Highland Rim, and Valley and Ridge aquifers are 6.5, 7.4, and 6.6 in/yr, respectively. Gravity drainage characterizes ground-water flow in most surficial bedrock aquifer in Tennessee. Accordingly, a gravity yield analysis, which compares concurrent water-level and streamflow hydrographs, was used to estimate aquifer storage coefficient for nine study basins. The basin estimates range from 0.002 to 0.140; however, most estimates are within a narrow range of values, from 0.01 to 0.025. Accordingly, storage coefficient is estimated to be 0.01 for all aquifers in Middle and East Tennessee, with the exception of the aquifer in the inner part of the Central Basin, for which storage coefficient is estimated to be 0.002. Estimates of aquifer hydraulic

  7. Obesity Researches Over the Past 24 years: A Scientometrics Study in Middle East Countries

    PubMed Central

    Djalalinia, Shirin; Peykari, Niloofar; Qorbani, Mostafa; Moghaddam, Sahar Saeedi; Larijani, Bagher; Farzadfar, Farshad

    2015-01-01

    Background: Researchers, practitioners, and policy-makers call for updated valid evidences to monitor, prevent, and control of alarming trends of obesity. We quantify the trends of obesity/overweight researches outputs of Middle East countries. Methods: We systematically searched Scopus database as the only sources for multidisciplinary citation reports, with the most coverage in health and biomedicine disciplines for all related obesity/overweight publications, from 1990 to 2013. These scientometrics analysis assessed the trends of scientific products, citations, and collaborative papers in Middle East countries. We also provided Information on top institutions, journals, and collaborative research centers in the field of obesity/overweight. Results: Over 24-year period, the number of obesity/overweight publications and related citations in Middle East countries had increasing trend. Globally, during 1990–2013, 415,126 papers have been published, from them, 3.56% were affiliated to Middle East countries. Iran with 26.27%, compare with other countries in the regions, after Turkey (47.94%) and Israel (35.25%), had the third position. Israel, Turkey, and Iran were leading countries in citation analysis. The most collaborative country with Middle East countries was USA and within the region, the most collaborative country was Saudi Arabia. Conclusions: Despite the ascending trends in research outputs, more efforts required for promotion of collaborative partnerships. Results could be useful for better health policy and more planned studies in this field. These findings also could be used for future complementary analysis. PMID:26015861

  8. Intravenous drug abuse and tricuspid valve endocarditis: Growing trends in the Middle East Gulf region

    PubMed Central

    Panduranga, Prashanth; Al-Abri, Seif; Al-Lawati, Jawad

    2013-01-01

    Traditionally, tricuspid valve endocarditis is uncommon in the Middle East region. However, recent global data indicate growing trends in the use of illicit drug abuse, specifically injectable heroin, in the Middle East Gulf region. The presence of many transit port services in the Middle East Gulf States has led to smuggling of substance abuse drugs in the region. The Middle East Gulf States, currently a transit market, are also becoming a growing consumer market in view of the increased substance abuse in the youth. However, there is a paucity of data with respect to the prevalence or incidence of tricuspid valve endocarditis in the region, probably due to underdiagnosis or underreporting. A high index of suspicion of tricuspid valve endocarditis is essential in patients with a history of intravenous drug abuse. This article reviews the epidemiology of illicit drug abuse in the Middle East Gulf region, as well as the diagnosis and treatment of tricuspid valve endocarditis, and calls for all physicians in the region to be vigilant while dealing with intravenous drug abuse. PMID:24829628

  9. Recent Outbreaks of Rift Valley Fever in East Africa and the Middle East

    PubMed Central

    Himeidan, Yousif E.; Kweka, Eliningaya J.; Mahgoub, Mostafa M.; El Rayah, El Amin; Ouma, Johnson O.

    2014-01-01

    Rift Valley fever (RVF) is an important neglected, emerging, mosquito-borne disease with severe negative impact on human and animal health. Mosquitoes in the Aedes genus have been considered as the reservoir, as well as vectors, since their transovarially infected eggs withstand desiccation and larvae hatch when in contact with water. However, different mosquito species serve as epizootic/epidemic vectors of RVF, creating a complex epidemiologic pattern in East Africa. The recent RVF outbreaks in Somalia (2006–2007), Kenya (2006–2007), Tanzania (2007), and Sudan (2007–2008) showed extension to districts, which were not involved before. These outbreaks also demonstrated the changing epidemiology of the disease from being originally associated with livestock, to a seemingly highly virulent form infecting humans and causing considerably high-fatality rates. The amount of rainfall is considered to be the main factor initiating RVF outbreaks. The interaction between rainfall and local environment, i.e., type of soil, livestock, and human determine the space-time clustering of RVF outbreaks. Contact with animals or their products was the most dominant risk factor to transfer the infection to humans. Uncontrolled movement of livestock during an outbreak is responsible for introducing RVF to new areas. For example, the virus that caused the Saudi Arabia outbreak in 2000 was found to be the same strain that caused the 1997–98 outbreaks in East Africa. A strategy that involves active surveillance with effective case management and diagnosis for humans and identifying target areas for animal vaccination, restriction on animal movements outside the affected areas, identifying breeding sites, and targeted intensive mosquito control programs has been shown to succeed in limiting the effect of RVF outbreak and curb the spread of the disease from the onset. PMID:25340047

  10. Recent outbreaks of rift valley Fever in East Africa and the middle East.

    PubMed

    Himeidan, Yousif E; Kweka, Eliningaya J; Mahgoub, Mostafa M; El Rayah, El Amin; Ouma, Johnson O

    2014-01-01

    Rift Valley fever (RVF) is an important neglected, emerging, mosquito-borne disease with severe negative impact on human and animal health. Mosquitoes in the Aedes genus have been considered as the reservoir, as well as vectors, since their transovarially infected eggs withstand desiccation and larvae hatch when in contact with water. However, different mosquito species serve as epizootic/epidemic vectors of RVF, creating a complex epidemiologic pattern in East Africa. The recent RVF outbreaks in Somalia (2006-2007), Kenya (2006-2007), Tanzania (2007), and Sudan (2007-2008) showed extension to districts, which were not involved before. These outbreaks also demonstrated the changing epidemiology of the disease from being originally associated with livestock, to a seemingly highly virulent form infecting humans and causing considerably high-fatality rates. The amount of rainfall is considered to be the main factor initiating RVF outbreaks. The interaction between rainfall and local environment, i.e., type of soil, livestock, and human determine the space-time clustering of RVF outbreaks. Contact with animals or their products was the most dominant risk factor to transfer the infection to humans. Uncontrolled movement of livestock during an outbreak is responsible for introducing RVF to new areas. For example, the virus that caused the Saudi Arabia outbreak in 2000 was found to be the same strain that caused the 1997-98 outbreaks in East Africa. A strategy that involves active surveillance with effective case management and diagnosis for humans and identifying target areas for animal vaccination, restriction on animal movements outside the affected areas, identifying breeding sites, and targeted intensive mosquito control programs has been shown to succeed in limiting the effect of RVF outbreak and curb the spread of the disease from the onset. PMID:25340047

  11. Impacts of Climate Change on the Climate Extremes of the Middle East

    NASA Astrophysics Data System (ADS)

    Turp, M. Tufan; Collu, Kamil; Deler, F. Busra; Ozturk, Tugba; Kurnaz, M. Levent

    2016-04-01

    The Middle East is one of the most vulnerable regions to the impacts of climate change. Because of the importance of the region and its vulnerability to global climate change, the studies including the investigation of projected changes in the climate of the Middle East play a crucial role in order to struggle with the negative effects of climate change. This research points out the relationship between the climate change and climate extremes indices in the Middle East and it investigates the changes in the number of extreme events as described by the joint CCl/CLIVAR/JCOMM Expert Team (ET) on Climate Change Detection and Indices (ETCCDI). As part of the study, the regional climate model (RegCM4.4) of the Abdus Salam International Centre for Theoretical Physics (ICTP) is run to obtain future projection data. This research has been supported by Boǧaziçi University Research Fund Grant Number 10421.

  12. Dust storm detection using random forests and physical-based approaches over the Middle East

    NASA Astrophysics Data System (ADS)

    Souri, Amir Hossein; Vajedian, Sanaz

    2015-07-01

    Dust storms are important phenomena over large regions of the arid and semi-arid areas of the Middle East. Due to the influences of dust aerosols on climate and human daily activities, dust detection plays a crucial role in environmental and climatic studies. Detection of dust storms is critical to accurately understand dust, their properties and distribution. Currently, remotely sensed data such as MODIS (Moderate Resolution Imaging Spectroradiometer) with appropriate temporal and spectral resolutions have been widely used for this purpose. This paper investigates the capability of two physical-based methods, and random forests (RF) classifier, for the first time, to detect dust storms using MODIS imagery. Since the physical-based approaches are empirical, they suffer from certain drawbacks such as high variability of thresholds depending on the underlying surface. Therefore, classification-based approaches could be deployed as an alternative. In this paper, the most relevant bands are chosen based on the physical effects of the major classes, particularly dust, cloud and snow, on both emissive infrared and reflective bands. In order to verify the capability of the methods, OMAERUV AAOD (aerosol absorption optical depth) product from OMI (Ozone Monitoring Instrument) sensor is exploited. In addition, some small regions are selected manually to be considered as ground truth for measuring the probability of false detection (POFD) and probability of missing detection (POMD). The dust class generated by RF is consistent qualitatively with the location and extent of dust observed in OMERAUV and MODIS true colour images. Quantitatively, the dust classes generated for eight dust outbreaks in the Middle East are found to be accurate from 7% and 6% of POFD and POMD respectively. Moreover, results demonstrate the sound capability of RF in classifying dust plumes over both water and land simultaneously. The performance of the physical-based approaches is found weaker than RF

  13. Middle Rio Grande Cooperative Water Model

    2005-11-01

    This is computer simulation model built in a commercial modeling product Called Studio Expert, developed by Powersim, Inc. The simulation model is built in a system dynamics environment, allowing the simulation of the interaction among multiple systems that are all changing over time. The model focuses on hydrology, ecology, demography, and economy of the Middle Rio Grande, with Water as the unifying feature.

  14. Multiple co-circulating HIV-1 subtypes in the Middle East and North Africa

    PubMed Central

    Rolland, Morgane; Modjarrad, Kayvon

    2015-01-01

    HIV-1 incidence has been increasing more rapidly in the Middle East and North Africa than in any other global region. Despite this trend, HIV epidemiology in the region remains poorly defined. We conducted an analysis of 3284 publicly available HIV-1 sequences from 15 countries in the Middle East and North Africa to better characterize the regional epidemic. A phylogenetic tree based on the reverse transcriptase gene revealed a complex mosaic of diverse HIV subtypes and circulating recombinant forms across the region. PMID:26091303

  15. Access to orphan drugs in the Middle East: Challenge and perspective

    PubMed Central

    Almalki, Ziyad S.; Alahmari, Abdullah K.; Guo, Jeff J.; Kelton, Christina M.L.

    2012-01-01

    Summary An orphan drug is a drug developed specifically to treat a rare medical condition. With a combined population of less than 400 million, about 2.8 million patients are estimated to be suffering from a rare disease in the Middle East. Some disorders such as hemoglobinopathy, glucose-6-phosphate dehydrogenase deficiency, autosomal recessive syndromes, and several metabolic disorders have a presence throughout the Middle East. In order to promote the treatment of these diseases, Middle Eastern governments need to facilitate education and training of healthcare personnel; develop and execute a method for obtaining and paying for orphan drugs; and, finally, provide tax, marketing, and other incentives to domestic and international firms to develop drugs specifically for the diseases of most importance to Middle Eastern patients. PMID:25343087

  16. Access to orphan drugs in the Middle East: Challenge and perspective.

    PubMed

    Almalki, Ziyad S; Alahmari, Abdullah K; Guo, Jeff J; Kelton, Christina M L

    2012-11-01

    An orphan drug is a drug developed specifically to treat a rare medical condition. With a combined population of less than 400 million, about 2.8 million patients are estimated to be suffering from a rare disease in the Middle East. Some disorders such as hemoglobinopathy, glucose-6-phosphate dehydrogenase deficiency, autosomal recessive syndromes, and several metabolic disorders have a presence throughout the Middle East. In order to promote the treatment of these diseases, Middle Eastern governments need to facilitate education and training of healthcare personnel; develop and execute a method for obtaining and paying for orphan drugs; and, finally, provide tax, marketing, and other incentives to domestic and international firms to develop drugs specifically for the diseases of most importance to Middle Eastern patients. PMID:25343087

  17. Sickle cell disease in Middle East Arab countries

    PubMed Central

    El-Hazmi, Mohsen A. F.; Al-Hazmi, Ali M.; Warsy, Arjumand S.

    2011-01-01

    The sickle cell (HbS) gene occurs at a variable frequency in the Middle Eastern Arab countries, with characteristic distribution patterns and representing an overall picture of blood genetic disorders in the region. The origin of the gene has been debated, but studies using β-globin gene haplotypes have ascertained that there were multiple origins for HbS. In some regions the HbS gene is common and exhibits polymorphism, while the reverse is true in others. A common causative factor for the high prevalence and maintenance of HbS and thalassaemia genes is malaria endemicity. The HbS gene also co-exists with other haemoglobin variants and thalassaemia genes and the resulting clinical state is referred to as sickle cell disease (SCD). In the Middle Eastern Arab countries, the clinical picture of SCD expresses two distinct forms, the benign and the severe forms, which are related to two distinct β-globin gene haplotypes. These are referred to as the Saudi-Indian and the Benin haplotypes, respectively. In a majority of the Middle Eastern Arab countries the HbS is linked to the Saudi-Indian haplotype, while in others it is linked to the Benin haplotype. This review outlines the frequency, distribution, clinical feature, management and prevention as well as gene interactions of the HbS genes with other haemoglobin disorders in the Middle Eastern Arab countries. PMID:22199098

  18. Seeking Truth in the Social Studies Classroom: Media Literacy, Critical Thinking and Teaching about the Middle East

    ERIC Educational Resources Information Center

    Sperry, Chris

    2006-01-01

    In this article, the author relates how he uses media literacy activities in his classroom when discussing issues involving the Middle East countries. He relates how this strategy helps him to teach accurate information about the most challenging and controversial aspects of the contemporary Middle East. He shares that through media analysis,…

  19. Analysis of the summertime buildup of tropospheric ozone abundances over the Middle East and North Africa as observed by the Tropospheric Emission Spectrometer instrument

    NASA Astrophysics Data System (ADS)

    Liu, Jane J.; Jones, Dylan B. A.; Worden, John R.; Noone, David; Parrington, Mark; Kar, Jay

    2009-03-01

    We use the GEOS-Chem chemical transport model to interpret observations of tropospheric ozone from the Tropospheric Emission Spectrometer (TES) satellite instrument in summer 2005. Observations from TES reveal elevated ozone in the middle troposphere (500-400 hPa) across North Africa and the Middle East. Observed ozone abundances in the middle troposphere are at a maximum in summer and a minimum in winter, consistent with the previously predicted summertime "Middle East ozone maximum." This summertime enhancement in ozone is associated with the Arabian and Sahara anticyclones, centered over the Zagros and Atlas Mountains, respectively. These anticyclones isolate the middle troposphere over northeast Africa and the Middle East, with westerlies to the north and easterlies to the south, facilitating the buildup of ozone. Over the Middle East, we find that in situ production and transport from Asia provides comparable contributions of 30-35% to the ozone buildup. Over North Africa, in situ production is dominant (at about 20%), with transport from Asia, North America, and equatorial Africa each contributing about 10-15% to the total ozone. We find that although the eastern Mediterranean is characterized by strong descent in the middle and upper troposphere in summer, transport from the boundary layer accounts for about 25% of the local Middle Eastern contribution to the ozone enhancement in the middle troposphere. This upward transport of boundary layer air is associated with orographic lifting along the Zagros Mountains in Iran and the Asir and Hijaz Mountain ranges in Saudi Arabia, and is consistent with TES observations of deuterated water.

  20. Enhancing Services for Students with Mild Disabilities in the Middle East Gulf Region: A Kuwait Initiative

    ERIC Educational Resources Information Center

    Al-Hilawani, Yasser A.; Koch, Kourtland R.; Braaten, Sheldon R.

    2008-01-01

    At a conference, titled: "Childhood Disabilities: Assessment and Early Intervention" held between March 20-22, 2006, at Kuwait University, a range of discussion topics were considered that would enhance and design specific best practices in special education for the Middle East Arab Gulf region. Governmental representatives, post-secondary…

  1. The American Role in Education in the Middle East: Ideology and Experiment, 1920-1940

    ERIC Educational Resources Information Center

    Ment, David M.

    2011-01-01

    In a significant 1925 essay, "Western Education in Moslem Lands", Paul Monroe addressed the emerging cultural and political forces faced by American educators in the Middle East. Monroe was widely recognised at the time as editor of the Cyclopedia of Education and director of the International Institute of Teachers College, Columbia University.…

  2. Internationalisation in US Higher Education: Studying the Middle East in the American University

    ERIC Educational Resources Information Center

    Miller-Idriss, Cynthia; Worden, Elizabeth Anderson

    2010-01-01

    This paper examines the organisation of the production of knowledge about international issues in US higher education, drawing on six case studies of Middle East studies. We review three key findings. First, we suggest that the American model for studying "the international" is rooted in a default, and outmoded, way of thinking about international…

  3. Revolution and Journalism Higher Education in the Middle East/North Africa Region

    ERIC Educational Resources Information Center

    Schafer, Shaun T.

    2012-01-01

    The disruptions brought by the Arab Spring revolutions in the Middle East/North Africa (MENA) region in 2010-2011 created a series of personal and professional challenges for those involved in higher education in journalism in the region. This research uses narrative inquiry to examine the impact revolution had on a group of educators in the MENA…

  4. Becoming Jordan's Writers: Developing Powerful Writing Instruction in the Middle East

    ERIC Educational Resources Information Center

    Lehman, Christopher; DeLiddo, Emily

    2010-01-01

    The United States involvement in the Middle East has been prominent in our recent national history, sometimes clouded by myths and misrepresentations of the people of that region of the world. This article details the experiences of teacher-researchers working with teachers and students in Amman, Jordan, to develop powerful English writing…

  5. Faculty Response to Ethical Issues at an American University in the Middle-East

    ERIC Educational Resources Information Center

    Tabsh, Sami W.; El Kadi, Hany A.; Abdelfatah, Akmal S.

    2012-01-01

    Purpose: The objective of this study is to get feedback on faculty perception of ethical issues related to teaching, scholarship and service at a relatively new American-style university in the Middle-East. Design/methodology/approach: A questionnaire involving 21 scenarios with multiple choice answers was developed and distributed to all faculty…

  6. TeachMideast: An Educational Initiative of the Middle East Policy Council

    ERIC Educational Resources Information Center

    Petzen, Barbara

    2010-01-01

    In this article, the author presents an activity wherein she uses the first Arab Human Development Report to examine not only the levels and measures of development in the Arab countries of the Middle East, but also to examine the act of measuring itself. The goal of the Arab Human Development Report is to measure "development in all its…

  7. Escaping from Sunday School: Teaching "The Middle East" in the Setting of Religion

    ERIC Educational Resources Information Center

    Marten, Michael

    2011-01-01

    The article argues that, in the teaching of religion at undergraduate level, many students approach understanding the historical or contemporary Middle East in ways that are coloured by what they think is biblical knowledge or basic Christian beliefs. This is less noticeable for students in disciplines such as history or politics. Many history or…

  8. Conventional Middle East arms control: Impact of the end of the cold war. Study project report

    SciTech Connect

    Johnson, L.L.; Johnsen, W.T.

    1993-03-31

    The end of the Gulf War brought to the forefront concern for dangers posed by unrestrained militarization of the Middle East. In response, on 29 May 1991 President Bush unveiled a comprehensive Middle East arms control policy in a speech at the U.S. Air Force Academy. A key element of the policy banned the sale of the most dangerous conventional weapons to the region. Although the major arms suppliers (which also happen to be the five permanent members of the U.N. Security Council) have held a series of high level meetings to discuss options for restricting sales to the region, all continue conventional arms transfers to the Middle East and are likely to continue to do so. This paper contends that the end of the Cold War put additional economic pressure on the major suppliers to export arms to the Middle East; and, their interests are so compelling that the suppliers are unlikely to support President Bush's proposal. This position is supported by analyzing the interests that influence major arms suppliers to sell arms abroad. The format for this analysis includes an assessment of: each country's interest in selling arms during the Cold War; the impact of the Cold War's end on those interests; and whether the post Cold War interests conflict with President Bush's conventional arms control proposal. The paper concludes with recommendations for US policy in the region.

  9. Mortality Risk Factors for Middle East Respiratory Syndrome Outbreak, South Korea, 2015.

    PubMed

    Majumder, Maimuna S; Kluberg, Sheryl A; Mekaru, Sumiko R; Brownstein, John S

    2015-11-01

    As of July 15, 2015, the South Korean Ministry of Health and Welfare had reported 186 case-patients with Middle East respiratory syndrome in South Korea. For 159 case-patients with known outcomes and complete case histories, we found that older age and preexisting concurrent health conditions were risk factors for death.

  10. Crisis Paper No. 32. The Middle East and the Super Powers.

    ERIC Educational Resources Information Center

    Critchley, Julian, Ed.

    This "Crisis Paper" examines the events of October, 1973, relating to the Middle East war. A chronology of events during the month is established, followed by short editorial commentary. A multi-national view of the situation is developed, quoting newspapers and journals from France, West Germany, USSR, China, Switzerland, Austria, Egypt, Lebanon,…

  11. Dissemination of carbapenemases producing Gram negative bacteria in the Middle East

    PubMed Central

    Zahedi bialvaei, Abed; Samadi kafil, Hossein; Ebrahimzadeh Leylabadlo, Hamed; Asgharzadeh, Mohammad; Aghazadeh, Mohammad

    2015-01-01

    The emergence and spread of carbapenemase-producing bacteria, that hydolyze most β-lactams, including carbapenems, are a major concern of public health system worldwide, particularly in the Middle East area. Since the plasmids harboring resistance genes could be spread across other bacterial populations, detection of carbapenemase-producing organisms has become more problematic. These organisms produce different types of enzymes including the most prevalent types including KPC, VIM, IMP, NDM, and OXA-48. Carbapenemase producers are mostly identified among Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii. This study reviewed almost all papers, which conducted in the Middle East. In order to decrease the spread of resistance, the regional cooperation has been emphasized by the Middle East countries. The highest resistance, which is mediated by KPC has been observed in Afghanistan, Saudi Arabia and Jordan followed by NDM in Pakistan and OXA in Turkey and Pakistan. It is important to mention that the spread of these types have been reported sporadically in the other countries of this area. This review described the widespread carbapenemases in the Middle East area, which have been identified in an alarming rate. PMID:26719779

  12. Acute middle East respiratory syndrome coronavirus infection in livestock Dromedaries, Dubai, 2014.

    PubMed

    Wernery, Ulrich; Corman, Victor M; Wong, Emily Y M; Tsang, Alan K L; Muth, Doreen; Lau, Susanna K P; Khazanehdari, Kamal; Zirkel, Florian; Ali, Mansoor; Nagy, Peter; Juhasz, Jutka; Wernery, Renate; Joseph, Sunitha; Syriac, Ginu; Elizabeth, Shyna K; Patteril, Nissy Annie Georgy; Woo, Patrick C Y; Drosten, Christian

    2015-06-01

    Camels carry Middle East respiratory syndrome coronavirus, but little is known about infection age or prevalence. We studied >800 dromedaries of all ages and 15 mother-calf pairs. This syndrome constitutes an acute, epidemic, and time-limited infection in camels <4 years of age, particularly calves. Delayed social separation of calves might reduce human infection risk.

  13. Launching of an American Medical College in the Middle East: "Educational Challenges in a Multicultural Environment"

    ERIC Educational Resources Information Center

    Hajjar, David P.; Gotto, Antonio M., Jr.

    2013-01-01

    The graduation of the first class of medical students in May 2008 from the Weill Cornell Medical College in Qatar (WCMC-Q), Cornell University's branch campus in the Middle East, was the first time that an M.D. degree from an American university was awarded abroad. It marked a milestone in American higher education. The establishment of WCMC-Q is…

  14. An Empirical Study of the Distributional Changes in Higher Education among East, Middle and West China

    ERIC Educational Resources Information Center

    Jiang, Chunjiao; Li, Song

    2008-01-01

    Based on the quantitative research and comparative study method, this paper attempts to make a systematic study and analysis of regional differences which have existed since 1949 in higher education among East, Middle and West China. The study is intended to explore the causes, regional differences, social changes, and their co-related…

  15. Gas projects surge in the Middle East as governments seek new revenue sources

    SciTech Connect

    Williams, M.D.

    1997-02-24

    The rapid development of natural gas and condensate reserves in the Middle East results from a simple motivation: the desire of governments to earn revenues. For the past decade, Middle East governments have run budget deficits, which they funded by drawing down foreign assets and issuing debt. Now in the process of structural economic reform, they have begun to use an under-utilized resource--natural gas, of which Middle East governments own about one third of the world`s reserves. Governments receive revenues from several sources in natural gas developments, which makes the projects very attractive. Revenue comes from the sale of the natural gas in the domestic market and, if exported, the international market; the sale of associated condensates; the additional exports of crude oil or refined products if natural gas is substituted for refined products in domestic markets; the increased sale of crude oil if natural gas is injected into reservoirs to maintain pressure; and the sale of petrochemicals where natural gas is used as feedstock. Large projects under way in the Middle East highlight the consequences of multiple revenue sources and interlinked costs of natural gas and condensate development. Other countries in the region are undertaking similar projects, so examples cited represent only a portion of what is occurring. The paper describes Abu Dhabi, Qatar, Saudi Arabia, and Iran.

  16. Bioinformatics in Middle East Program Curricula--A Focus on the Arabian Gulf

    ERIC Educational Resources Information Center

    Loucif, Samia

    2014-01-01

    The purpose of this paper is to investigate the inclusion of bioinformatics in program curricula in the Middle East, focusing on educational institutions in the Arabian Gulf. Bioinformatics is a multidisciplinary field which has emerged in response to the need for efficient data storage and retrieval, and accurate and fast computational and…

  17. A Song for Humanistic Education: Pedagogy and Politics in the Middle East

    ERIC Educational Resources Information Center

    Herrera, Linda A.

    2008-01-01

    Background/Context: If we take as a given the desirability of an education that promotes principles of respect, pluralism, rational critical inquiry, compassion, innovation, and excellence, then humanistic pedagogies should be paramount to that educational vision. Yet humanistic education in the Middle East has been on the demise in past decades…

  18. Oil and the economic geography of the Middle East and North Africa

    SciTech Connect

    Kortepeter, C.M. )

    1990-01-01

    This book gives us the opportunity to follow the development of the field of economic geography as applied to the Middle East during the past half century. The materials are arranged under the following three headings: Geography and Petroleum: Boundaries and Boundary Disputes: and Social Geography.

  19. Contact Tracing for Imported Case of Middle East Respiratory Syndrome, China, 2015

    PubMed Central

    Kang, Min; Zhong, Haojie; Hou, Jie; Wang, Jun; Li, Jiansen; Wu, Jie; He, Jianfeng; Lin, Jinyan; Zhang, Yonghhui

    2016-01-01

    Confirmation of an imported case of infection with Middle East respiratory syndrome coronavirus in China triggered intensive contact tracing and mandatory monitoring. Using a hotline and surveillance video footage was effective for tracing all 110 identified contacts. Contact monitoring detected no secondary transmission of infection in China. PMID:27532887

  20. Selected Factors Influencing Student Enrollment at Area Vocational Schools in East, Middle and West Tennessee.

    ERIC Educational Resources Information Center

    Lindsey, Willie E., Jr.

    An analysis was made of selected factors influencing students to enroll in area postsecondary vocational schools in East, Middle, and West Tennessee. Four hundred forty-three students were surveyed concerning three broad areas of dependent variables: domestic environment, perceived opportunities, and assessment of program. Data were analyzed by…

  1. At the Crossroads of the World: Women of the Middle East

    ERIC Educational Resources Information Center

    Crocco, Margaret S.; Pervez, Nadia; Katz, Meredith

    2009-01-01

    The authors offer a brief introduction to the history of women of the Middle East, with a focus on three major religions (Judaism, Christianity, and Islam). Schools are paying increased attention to teaching world history, but they are giving too little attention to incorporating women as part of world history. One of the major dividing lines…

  2. International Trends in Health Science Librarianship Part 18: The Middle East (Iran, Qatar and Turkey).

    PubMed

    Zeraatkar, Kimia; Ayatollahi, Haleh; Havlin, Tracy; Neves, Karen; Şendir, Mesra

    2016-06-01

    This is the 18th in a series of articles exploring international trends in health science librarianship in the 21st century. The focus of the present issue is the Middle East (Iran, Qatar and Turkey). The next feature column will investigate trends in the Balkan States JM.

  3. History Didactics in the Post Cold War World: Central Asia, the Middle East, and China.

    ERIC Educational Resources Information Center

    Forsyth, Louise; Gould, David; Lawrence, David

    2000-01-01

    Examines three key geographical regions, Central Asia, the Middle East, and China, discussing how the political changes resulting from the end of the Cold War have affected each area. Attempts to demonstrate how teachers can address these changes in their classrooms. (CMK)

  4. A Matter of Perspective: Teaching International Relations in the Middle East

    ERIC Educational Resources Information Center

    Burns, Sean

    2014-01-01

    In this article, the author looks at several popular international relations textbooks in light of his experience teaching students in the Middle East. He finds that, for their many strengths, most of the books lack some key features that would make them more useful for students abroad.

  5. Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015

    PubMed Central

    Seong, Moon-Woo; Kim, So Yeon; Corman, Victor Max; Kim, Taek Soo; Cho, Sung Im; Kim, Man Jin; Lee, Seung Jun; Lee, Jee-Soo; Seo, Soo Hyun; Ahn, Ji Soo; Yu, Byeong Su; Park, Nare; Oh, Myoung-don; Park, Wan Beom; Lee, Ji Yeon; Kim, Gayeon; Joh, Joon Sung; Jeong, Ina; Kim, Eui Chong

    2016-01-01

    During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins. PMID:26814649

  6. Seeing Other Sides: Nongame Simulations and Alternative Perspectives of Middle East Conflict

    ERIC Educational Resources Information Center

    Baylouny, Anne Marie

    2009-01-01

    Simple role-play simulations can not only demonstrate the dynamics of a conflict but also create awareness of multiple perspectives even among populations relatively set in their opinions. To teach my student population of military officers, I utilize simple, nongame simulations of multisided Middle East conflicts that not only facilitate learning…

  7. Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection

    PubMed Central

    Kim, So Yeon; Park, Sun Jae; Cho, Sook Young; Cha, Ran-hui; Jee, Hyeon-Gun; Kim, Gayeon; Shin, Hyoung-Shik; Kim, Yeonjae; Jung, Yu Mi; Yang, Jeong-Sun; Kim, Sung Soon; Cho, Sung Im; Kim, Man Jin; Lee, Jee-Soo; Lee, Seung Jun; Seo, Soo Hyun; Park, Sung Sup

    2016-01-01

    We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA was detected in blood from 33% of patients at initial diagnosis, and the detection preceded a worse clinical course. PMID:27479636

  8. Modern Tools of Propaganda: Television Treatments of National Anthems in the Middle East.

    ERIC Educational Resources Information Center

    Leidman, Mary Beth

    Because of the close proximity of countries in the Middle East, broadcast signals freely cross national boundaries, bringing not always friendly endemic populations into contact with each other through radio and television programming--a fact that has not been lost on the governments which fund broadcasting facilities. National anthems are…

  9. Improving the Preparation of Middle Grades Mathematics Teachers: The Case of East Carolina University.

    ERIC Educational Resources Information Center

    Preston, Ron; Rachlin, Sid; DeBellis, Valerie; Robinson, Zachary; Sinicrope, Rose

    This paper describes the mathematics concentration program at East Carolina University (ECU) that is taken by preservice middle grades teachers intending to teach mathematics. Following a brief examination of the forces that impacted the formation of this mathematics concentration, this paper describes the program and highlights five courses from…

  10. Teaching East Asia: China, Japan, Korea. Lesson Plans for Middle School Teachers. Volume I.

    ERIC Educational Resources Information Center

    Aiken, Geoff; Benton, Susan; Duvall, James; Eltzroth, Diane; Hooyberg, Astrid; Keim, Marilee; Norris, Elizabeth; Smith, Peggy; Vogel, Kathy; Williams, Steven

    This volume contains 40 lesson plans that were written for middle school teachers to help students learn about East Asia. The lessons are organized across five themes: (1) "People, Places & Environment"; (2) "Technology, Production, Distribution & Consumption"; (3) "Cultures, Continuity, Change"; (4) Institutions, Power & Government"; and (5)…

  11. Teaching East Asia: China, Japan, Korea. Lesson Plans for Middle School Teachers. Volume II.

    ERIC Educational Resources Information Center

    Beville, Francie; Boone, Mark; Chapman, Kelly; Crump, Claudia; Curtis, Lonnie; Erickson, Stacy; Kaiser-Polge, Tami; Klus, John A.; Luebbehusen, Mary Lou; Rea, Patrick S.; Ward, Mary E.

    This volume contains 23 lesson plans that were written for middle school teachers to help students learn about East Asia. The lessons are organized across six themes: (1) "People, Places & Environment"; (2) "Technology, Production, Distribution & Consumption"; (3) "Cultures, Continuity, and Change"; (4) "Aesthetics, Celebrations and Values"; (5)…

  12. Contact Tracing for Imported Case of Middle East Respiratory Syndrome, China, 2015.

    PubMed

    Kang, Min; Song, Tie; Zhong, Haojie; Hou, Jie; Wang, Jun; Li, Jiansen; Wu, Jie; He, Jianfeng; Lin, Jinyan; Zhang, Yonghhui

    2016-09-01

    Confirmation of an imported case of infection with Middle East respiratory syndrome coronavirus in China triggered intensive contact tracing and mandatory monitoring. Using a hotline and surveillance video footage was effective for tracing all 110 identified contacts. Contact monitoring detected no secondary transmission of infection in China. PMID:27532887

  13. Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection.

    PubMed

    Kim, So Yeon; Park, Sun Jae; Cho, Sook Young; Cha, Ran-Hui; Jee, Hyeon-Gun; Kim, Gayeon; Shin, Hyoung-Shik; Kim, Yeonjae; Jung, Yu Mi; Yang, Jeong-Sun; Kim, Sung Soon; Cho, Sung Im; Kim, Man Jin; Lee, Jee-Soo; Lee, Seung Jun; Seo, Soo Hyun; Park, Sung Sup; Seong, Moon-Woo

    2016-10-01

    We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA was detected in blood from 33% of patients at initial diagnosis, and the detection preceded a worse clinical course. PMID:27479636

  14. Experimental Infection and Response to Rechallenge of Alpacas with Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Crameri, Gary; Klein, Reuben; Foord, Adam; Yu, Meng; Riddell, Sarah; Haining, Jessica; Johnson, Dayna; Hemida, Maged G.; Barr, Jennifer; Peiris, Malik; Middleton, Deborah; Wang, Lin-Fa

    2016-01-01

    We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus. PMID:27070733

  15. Refinement of late-Early and Middle Miocene diatom biostratigraphy for the east coast of the United States

    USGS Publications Warehouse

    Barron, John A.; Browning, James; Sugarman, Peter; Miller, Kenneth G.

    2013-01-01

    Integrated Ocean Drilling Program (IODP) Expedition 313 continuously cored Lower to Middle Miocene sequences at three continental shelf sites off New Jersey, USA. The most seaward of these, Site M29, contains a well-preserved Early and Middle Miocene succession of planktonic diatoms that have been independently correlated with the geomagnetic polarity time scale derived in studies from the equatorial and North Pacific. Shallow water diatoms (species of Delphineis, Rhaphoneis, and Sceptroneis) dominate in onshore sequences in Maryland and Virginia, forming the basis for the East Coast Diatom Zones (ECDZ). Integrated study of both planktonic and shallow water diatoms in Hole M29A as well as in onshore sequences in Maryland (the Baltimore Gas and Electric Company well) and Delaware (the Ocean Drilling Program Bethany Beach corehole) allows the refinement of ECDZ zones into a high-resolution biochronology that can be successfully applied in both onshore and offshore regions of the East Coast of the United States. Strontium isotope stratigraphy supports the diatom biochronology, although for much of the Middle Miocene it suggests ages that are on average 0.4 m.y. older. The ECDZ zonal definitions are updated to include evolutionary events of Delphineis species, and regional occurrences of important planktonic diatom marker taxa are included. Updated taxonomy, reference to published figures, and photographic images are provided that will aid in the application of this diatom biostratigraphy.

  16. Only the bad died young in the ancient Middle East.

    PubMed

    Arnett, W S

    1985-01-01

    Biblical writers generally viewed old age as a reward for righteousness and piety. Consequently, they stressed the belief that the elderly were blessed and that they should be venerated. While life expectancy was usually below forty years, there are exceptional cases on record of individuals--men and women--living to advanced old ages. An analysis of these special few cases and a discussion of extra-Biblical texts shows that other ancient Middle Eastern societies held attitudes toward aging and the aged comparable to those expressed in the Hebrew Bible.

  17. Abrupt recent trend changes in atmospheric nitrogen dioxide over the Middle East

    PubMed Central

    Lelieveld, Jos; Beirle, Steffen; Hörmann, Christoph; Stenchikov, Georgiy; Wagner, Thomas

    2015-01-01

    Nitrogen oxides, released from fossil fuel use and other combustion processes, affect air quality and climate. From the mid-1990s onward, nitrogen dioxide (NO2) has been monitored from space, and since 2004 with relatively high spatial resolution by the Ozone Monitoring Instrument. Strong upward NO2 trends have been observed over South and East Asia and the Middle East, in particular over major cities. We show, however, that a combination of air quality control and political factors, including economical crisis and armed conflict, has drastically altered the emission landscape of nitrogen oxides in the Middle East. Large changes, including trend reversals, have occurred since about 2010 that could not have been predicted and therefore are at odds with emission scenarios used in projections of air pollution and climate change in the early 21st century. PMID:26601240

  18. Abrupt recent trend changes in atmospheric nitrogen dioxide over the Middle East.

    PubMed

    Lelieveld, Jos; Beirle, Steffen; Hörmann, Christoph; Stenchikov, Georgiy; Wagner, Thomas

    2015-08-01

    Nitrogen oxides, released from fossil fuel use and other combustion processes, affect air quality and climate. From the mid-1990s onward, nitrogen dioxide (NO2) has been monitored from space, and since 2004 with relatively high spatial resolution by the Ozone Monitoring Instrument. Strong upward NO2 trends have been observed over South and East Asia and the Middle East, in particular over major cities. We show, however, that a combination of air quality control and political factors, including economical crisis and armed conflict, has drastically altered the emission landscape of nitrogen oxides in the Middle East. Large changes, including trend reversals, have occurred since about 2010 that could not have been predicted and therefore are at odds with emission scenarios used in projections of air pollution and climate change in the early 21st century. PMID:26601240

  19. Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir.

    PubMed

    Mohd, Hamzah A; Al-Tawfiq, Jaffar A; Memish, Ziad A

    2016-01-01

    Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) is a novel coronavirus discovered in 2012 and is responsible for acute respiratory syndrome in humans. Though not confirmed yet, multiple surveillance and phylogenetic studies suggest a bat origin. The disease is heavily endemic in dromedary camel populations of East Africa and the Middle East. It is unclear as to when the virus was introduced to dromedary camels, but data from studies that investigated stored dromedary camel sera and geographical distribution of involved dromedary camel populations suggested that the virus was present in dromedary camels several decades ago. Though bats and alpacas can serve as potential reservoirs for MERS-CoV, dromedary camels seem to be the only animal host responsible for the spill over human infections. PMID:27255185

  20. Diabetes research in Middle East countries; a scientometrics study from 1990 to 2012

    PubMed Central

    Peykari, Niloofar; Djalalinia, Shirin; Kasaeian, Amir; Naderimagham, Shohreh; Hasannia, Tahereh; Larijani, Bagher; Farzadfar, Farshad

    2015-01-01

    Background: Diabetes burden is a serious warning for urgent action plan across the world. Knowledge production in this context could provide evidences for more efficient interventions. Aimed to that, we quantify the trend of diabetes research outputs of Middle East countries focusing on the scientific publication numbers, citations, and international collaboration. Materials and Methods: This scientometrics study was performed based on the systematic analysis through three international databases; ISI, PubMed, and Scopus from 1990 to 2012. International collaboration of Middle East countries and citations was analyzed based on Scopus. Diabetes’ publications in Iran specifically were assessed, and frequent used terms were mapped by VOSviewer software. Results: Over 23-year period, the number of diabetes publications and related citations in Middle East countries had increasing trend. The number of articles on diabetes in ISI, PubMed, and Scopus were respectively; 13,994, 11,336, and 20,707. Turkey, Israel, Iran, Saudi Arabia, and Egypt have devoted the five top competition positions. In addition, Israel, Turkey, and Iran were leading countries in citation analysis. The most collaborative country with Middle East countries was USA and within the region, the most collaborative country was Saudi Arabia. Iran in all databases stands on third position and produced 12.7% of diabetes publications within region. Regarding diabetes researches, the frequent used terms in Iranian articles were “effect,” “woman,” and “metabolic syndrome.” Conclusion: Ascending trend of diabetes research outputs in Middle East countries is appreciated but encouraging to strategic planning for maintaining this trend, and more collaboration between researchers is needed to regional health promotion. PMID:26109972

  1. High naturally occurring radioactivity in fossil groundwater from the Middle East.

    PubMed

    Vengosh, Avner; Hirschfeld, Daniella; Vinson, David; Dwyer, Gary; Raanan, Hadas; Rimawi, Omar; Al-Zoubi, Abdallah; Akkawi, Emad; Marie, Amer; Haquin, Gustavo; Zaarur, Shikma; Ganor, Jiwchar

    2009-03-15

    High levels of naturally occurring and carcinogenic radium isotopes have been measured in low-saline and oxic groundwater from the Rum Group of the Disi sandstone aquifer in Jordan. The combined 228Ra and 226Ra activities are up to 2000% higher than international drinking water standards. Analyses of the host sandstone aquifer rocks show 228Ra and 226Ra activities and ratios that are consistent with previous reports of sandstone rocks from different parts of the world. A compilation of previous data in groundwater from worldwide sandstone aquifers shows large variations in Ra activities regardless of the groundwater salinity. On the basis of the distribution of the four Ra isotopes and the ratios of the short- to long-lived Ra isotopes, we postulate that Ra activity in groundwater is controlled by the balance of radioactive decay of parent Th isotopes on aquifer solids, decay of the dissolved radium isotopes, and adsorption of dissolved Ra on solid surfaces. The availability of surface adsorption sites, which depends on the clay content in the aquifer rocks, is therefore an important constraint for Ra activity in sandstone aquifers. These findings raise concerns about the safety of this and similar nonrenewable groundwater reservoirs, exacerbating the already severe water crisis in the Middle East.

  2. Middle East: Iran isn't missed much

    SciTech Connect

    Not Available

    1980-08-15

    A concerted effort to further develop productive capacity is evident in most Middle Eastern Countries, through exploration, field development, and secondary recovery. Saudi Arabia, Iraq, and Abu Dhabi all plan expanded petroleum industry programs in 1980. Oil production in Saudi Arabia through the first one-half of 1980 averaged 9.5 million bpd, and the Saudis are proceeding with the large-scale associated gas utilization and industrialization program. Iraq's near-term interest is in development of the Majnoon Discovery. Abu Dhabi is continuing efforts to complete development of a giant offshore field and finalize an onshore/offshore associated gas utilization facility. Only Iran and Kuwait are expected to be relatively inactive in petroleum programs during the remainder of 1980. Individual country reports are presented for Saudi Arabia, Iraq, Abu Dhabi, Dubai, Iran, Kuwait, the Divided Neutral Zone, Qatar, Oman, Bahrain, Syria, Turkey, Israel, Jordan, South Yemen, and Yemen Arab Republic.

  3. Impacts of anthropogenic and natural sources on free tropospheric ozone over the Middle East

    NASA Astrophysics Data System (ADS)

    Jiang, Zhe; Miyazaki, Kazuyuki; Worden, John R.; Liu, Jane J.; Jones, Dylan B. A.; Henze, Daven K.

    2016-05-01

    Significant progress has been made in identifying the influence of different processes and emissions on the summertime enhancements of free tropospheric ozone (O3) at northern midlatitude regions. However, the exact contribution of regional emissions, chemical and transport processes to these summertime enhancements is still not well quantified. Here we focus on quantifying the influence of regional emissions on the summertime O3 enhancements over the Middle East, using updated reactive nitrogen (NOx) emissions. We then use the adjoint of the GEOS-Chem model with these updated NOx emissions to show that the global total contribution of lightning NOx on middle free tropospheric O3 over the Middle East is about 2 times larger than that from global anthropogenic sources. The summertime middle free tropospheric O3 enhancement is primarily due to Asian NOx emissions, with approximately equivalent contributions from Asian anthropogenic activities and lightning. In the Middle Eastern lower free troposphere, lightning NOx from Europe and North America and anthropogenic NOx from Middle Eastern local emissions are the primary sources of O3. This work highlights the critical role of lightning NOx on northern midlatitude free tropospheric O3 and the important effect of the Asian summer monsoon on the export of Asian pollutants.

  4. Hepatitis A virus in the Middle East and North Africa region: a new challenge.

    PubMed

    Melhem, N M; Talhouk, R; Rachidi, H; Ramia, S

    2014-01-01

    During the past three decades, a gradual shift in the age of infection with hepatitis A virus (HAV) from early childhood to adulthood has been observed. There is a general lack of updated data on HAV burden of disease, incidence and age-specific seroprevalence in countries of the Middle East and North Africa (MENA) region. The aim of this article is to review the published data on anti-HAV seroprevalence, an important tool to monitor infections rates, in countries of the MENA region and associated risk factors including water and socioeconomic data when available. Data on anti-HAV seroprevalence were found for 12 of 25 MENA countries. We show that MENA countries, similar to other areas in the world, have a clear shift in HAV incidence with a decline among young age groups and an increase among adults and older individuals. This would likely be associated with increased morbidity and increased risks of outbreaks among younger age groups. Consequently, the continuous surveillance of hepatitis A cases and the inclusion of hepatitis A vaccine in the expanded immunization programmes are needed in countries of the MENA.

  5. OBLIQUE VIEW OF SOUTH AND EAST SIDES OF WATER TREATMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    OBLIQUE VIEW OF SOUTH AND EAST SIDES OF WATER TREATMENT PLANT, VIEW TOWARDS NORTHWEST - Ortona Lock, Lock No. 2, Water Treatment Plant, Caloosahatchee River, Cross-State Canal, Okeechobee Intracoastal Waterway, Ortona, Glades County, FL

  6. OBLIQUE VIEW OF EAST AND NORTH SIDES OF WATER TREATMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    OBLIQUE VIEW OF EAST AND NORTH SIDES OF WATER TREATMENT PLANT, LOCK TENDER'S HOUSE IN BACKGROUND, VIEW TOWARDS SOUTHWEST - Ortona Lock, Lock No. 2, Water Treatment Plant, Caloosahatchee River, Cross-State Canal, Okeechobee Intracoastal Waterway, Ortona, Glades County, FL

  7. 8. LOOKING EAST FROM TOP OF WATER TOWER: VIEW SHOWS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. LOOKING EAST FROM TOP OF WATER TOWER: VIEW SHOWS BUILDING #626 AND PORTION OF QUADRANGLE - Fort Sam Houston, San Antonio Depot, Water-Watch Tower, Grayson Street & New Braunfels Avenue, San Antonio, Bexar County, TX

  8. Consensus recommendation for meningococcal disease prevention in children and adolescents in the Middle East region.

    PubMed

    Shibl, Atef; Tufenkeji, Haysam; Khalil, Mohamed; Memish, Ziad

    2012-03-01

    Facing the availability of the new generation of quadrivalent meningococcal conjugate vaccines (Menveo®, Menactra® and others pending for license) and their recent implementation in Saudi Arabia, experts from 11 countries of the Middle East region met at a "Meningococcal Leadership Forum" (MLF), which took place in May 2010 in Dubai. The participants of the conference discussed the importance of introducing the concept of conjugate vaccines - especially for children and adolescents - and elaborated a consensus recommendation to support healthcare professionals and decision makers with their expertise. In experts' opinion, conjugate vaccines are the best choice for the prevention of meningococcal disease caused by serogroups A, C, W-135 and Y. As quadrivalent meningococcal conjugate vaccines are registered and available in the Middle East region, they should replace plain polysaccharide vaccines and be integrated in pediatric and adolescent vaccination schedules, including infant vaccination concomitantly with basic EPI vaccines when licensed.

  9. Nuclear war in the Middle East: where is the voice of medicine and public health.

    PubMed

    Dallas, Cham E; Burkle, Frederick M

    2011-10-01

    Once again, the politically volatile Middle East and accompanying rhetoric has escalated the risk of a major nuclear exchange. Diplomatic efforts have failed to make the medical consequences of such an exchange a leading element in negotiations. The medical and academic communities share this denial. Without exaggeration, the harsh reality of the enormous consequences of an imminently conceivable nuclear war between Iran and Israel will encompass an unprecedented millions of dead and an unavoidable decline in public health and environmental devastation that would impact major populations in the Middle East for decades to come. Nuclear deterrence and the uncomfortable but real medical and public health consequences must become an integral part of a broader global health diplomacy that emphasizes health security along with poverty reduction and good governance. PMID:22509536

  10. Marshak Lectureship Talk: SESAME: An International Collaborative Science Project in the Middle East

    NASA Astrophysics Data System (ADS)

    Sowwan, Mukhles

    2010-02-01

    In this talk I will speak about the international collaborative science project SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East). SESAME is being developed under the umbrella of UNESCO and is modeled closely on CERN. The first beam line will be operational in 2012. Several hundred scientists from the region and other parts of the world are expected to use this facility, which will cover disciplines ranging from archaeology to the medical sciences and nanotechnology. The members of SESAME are (Bahrain, Cyprus, Egypt, Iran, Israel, Palestinian Authority, Jordan, Pakistan, Turkey). This makes SESAME a unique multidisciplinary centre in this part of the world. In addition, I will talk about the Nanotechnology Research at Al-Quds University, and my views on science and politics, and international collaboration, in a volatile environment like the Middle East. )

  11. Climate change as a draw bridge between Africa and the Middle East

    NASA Astrophysics Data System (ADS)

    Issar, Arie S.

    2010-07-01

    Since the very beginning of the human race, the Middle East served as a bridge between Africa-where our species first evolved-and the rest of the world. The passage over this bridge opened and closed with the global fluctuations of climate. The first glacial periods at the beginning of the Quaternary caused the greenhouse of equatorial Africa to become less hospitable, while making the desert belt of the Middle East more humid, green, and thus passable. Flint tools found along the shores of dried up lakes and swamps in the Negev Desert provide evidence that members of the first wave, Homo erectus, as well as the last wave, Homo sapiens, camped there en route to all the other continents.

  12. Consistent response of Indian summer monsoon to Middle East dust in observations and simulations

    NASA Astrophysics Data System (ADS)

    Jin, Q.; Wei, J.; Yang, Z.-L.; Pu, B.; Huang, J.

    2015-06-01

    The response of the Indian summer monsoon (ISM) circulation and precipitation to Middle East dust aerosols on sub-seasonal timescales is studied using observations and the Weather Research and Forecasting model with chemistry (WRF-Chem). Satellite data shows that the ISM rainfall in coastal southwest India, central and northern India, and Pakistan are closely associated with Middle East dust aerosols. The physical mechanism behind this dust-ISM rainfall connection is examined through ensemble simulations with and without dust emission. Each ensemble includes 16 members with various physical and chemical schemes to consider the model uncertainties in parameterizing shortwave radiation, the planetary boundary layer, and aerosol chemical mixing rules. Experiments show that dust aerosols increase rainfall by about 0.44 mm day-1 (~ 10%) in coastal southwest India, central and northern India, and northern Pakistan, a pattern consistent with the observed relationship. The ensemble mean rainfall response over India shows much stronger spatial correlation with the observed rainfall response than any of the ensemble members. The largest modeling uncertainties are from the boundary layer schemes, followed by shortwave radiation schemes. In WRF-Chem, the dust AOD over the Middle East shows the strongest correlation with the ISM rainfall response when dust AOD leads rainfall response by about 11 days. Further analyses show that the increased ISM rainfall is related to the enhanced southwesterly flow and moisture transport from the Arabian Sea to the Indian subcontinent, which are associated with the development of an anomalous low pressure system over the Arabian Sea, the southern Arabian Peninsula, and the Iranian Plateau due to dust-induced heating in the lower troposphere (800-500 hPa). This study demonstrates a thermodynamic mechanism that links remote desert dust emission in the Middle East to the ISM circulation and precipitation variability on sub-seasonal timescales

  13. Revised East-West Antarctic plate motions since the Middle Eocene

    NASA Astrophysics Data System (ADS)

    Granot, R.; Cande, S. C.; Stock, J.; Damaske, D.

    2010-12-01

    The middle Cenozoic (43-26 Ma) rifting between East and West Antarctica is defined by an episode of ultraslow seafloor spreading in the Adare Basin, located off northwestern Ross Sea. The absence of fracture zones and the lack of sufficient well-located magnetic anomaly picks have resulted in a poorly constrained kinematic model (Cande et al., 2000). Here we utilize the results from a dense aeromagnetic survey (Damaske et al., 2007) collected as part of GANOVEX IX 2005/06 campaign to re-evaluate the kinematics of the West Antarctic rift system since the Middle Eocene. We identify marine magnetic anomalies (anomalies 12o, 13o, 16y, and 18o) along a total of 25,000 km of the GPS navigated magnetic profiles. The continuation of these anomalies into the Northern Basin has allowed us to use the entire N-S length of this dataset in our calculations. A distinct curvature in the orientation of the spreading axis provides a strong constraint on our calculated kinematic models. The results from two- (East-West Antarctica) and three- (Australia-East Antarctica-West Antarctica) plate solutions agree well and create a cluster of rotation axes located south of the rift system, near the South Pole. These solutions reveal that spreading rate and direction, and therefore motion between East and West Antarctica, were steady between the Middle Eocene and Early Oligocene. Our kinematic solutions confirm the results of Davey and De Santis (2005) that the Victoria Land Basin has accommodated ~95 km of extension since the Middle Eocene. This magnetic pattern also provides valuable constraints on the post-spreading deformation of the Adare Basin (Granot et al., 2010). The Adare Basin has accommodated very little extension since the Late Oligocene (<7 km), but motion has probably increased southward. The details of this younger phase of motion are still crudely constrained.

  14. Outdoor particulate matter (PM) and associated cardiovascular diseases in the Middle East.

    PubMed

    Nasser, Zeina; Salameh, Pascale; Nasser, Wissam; Abou Abbas, Linda; Elias, Elias; Leveque, Alain

    2015-01-01

    Air pollution is a widespread environmental concern. Considerable epidemiological evidence indicates air pollution, particularly particulate matter (PM), as a major risk factor for cardiovascular diseases (CVD) in the developed countries. The main objective of our review is to assess the levels and sources of PM across the Middle East area and to search evidence for the relationship between PM exposure and CVD. An extensive review of the published literature pertaining to the subject (2000-2013) was conducted using PubMed, Medline and Google Scholar databases. We reveal that low utilization of public transport, ageing vehicle fleet and the increasing number of personal cars in the developing countries all contribute to the traffic congestion and aggravate the pollution problem. The annual average values of PM pollutants in the Middle East region are much higher than the World Health Organization 2006 guidelines (PM2.5 = 10 μg/m(3), PM10 = 20 μg/m(3)). We uncover evidence on the association between PM and CVD in 4 Middle East countries: Iran, Kingdom of Saudi Arabia, Qatar and the United Arab Emirates. The findings are in light of the international figures. Ambient PM pollution is considered a potential risk factor for platelet activation and atherosclerosis and has been found to be linked with an increased risk for mortality and hospital admissions due to CVD. This review highlights the importance of developing a strategy to improve air quality and reduce outdoor air pollution in the developing countries, particularly in the Middle East. Future studies should weigh the potential impact of PM on the overall burden of cardiac diseases. PMID:26216305

  15. Middle East Respiratory Syndrome Coronavirus during Pregnancy, Abu Dhabi, United Arab Emirates, 2013.

    PubMed

    Malik, Asim; El Masry, Karim Medhat; Ravi, Mini; Sayed, Falak

    2016-03-01

    As of June 19, 2015, the World Health Organization had received 1,338 notifications of laboratory-confirmed infection with Middle East respiratory syndrome coronavirus (MERS-CoV). Little is known about the course of or treatment for MERS-CoV in pregnant women. We report a fatal case of MERS-CoV in a pregnant woman administered combination ribavirin-peginterferon-α therapy.

  16. Outdoor particulate matter (PM) and associated cardiovascular diseases in the Middle East.

    PubMed

    Nasser, Zeina; Salameh, Pascale; Nasser, Wissam; Abou Abbas, Linda; Elias, Elias; Leveque, Alain

    2015-01-01

    Air pollution is a widespread environmental concern. Considerable epidemiological evidence indicates air pollution, particularly particulate matter (PM), as a major risk factor for cardiovascular diseases (CVD) in the developed countries. The main objective of our review is to assess the levels and sources of PM across the Middle East area and to search evidence for the relationship between PM exposure and CVD. An extensive review of the published literature pertaining to the subject (2000-2013) was conducted using PubMed, Medline and Google Scholar databases. We reveal that low utilization of public transport, ageing vehicle fleet and the increasing number of personal cars in the developing countries all contribute to the traffic congestion and aggravate the pollution problem. The annual average values of PM pollutants in the Middle East region are much higher than the World Health Organization 2006 guidelines (PM2.5 = 10 μg/m(3), PM10 = 20 μg/m(3)). We uncover evidence on the association between PM and CVD in 4 Middle East countries: Iran, Kingdom of Saudi Arabia, Qatar and the United Arab Emirates. The findings are in light of the international figures. Ambient PM pollution is considered a potential risk factor for platelet activation and atherosclerosis and has been found to be linked with an increased risk for mortality and hospital admissions due to CVD. This review highlights the importance of developing a strategy to improve air quality and reduce outdoor air pollution in the developing countries, particularly in the Middle East. Future studies should weigh the potential impact of PM on the overall burden of cardiac diseases.

  17. Laboratory Testing for Middle East Respiratory Syndrome Coronavirus, California, USA, 2013–2014

    PubMed Central

    Shahkarami, Mahtab; Yen, Cynthia; Glaser, Carol; Xia, Dongxiang; Watt, James

    2015-01-01

    Since Middle East respiratory syndrome coronavirus (MERS-CoV) first emerged, the California Department of Public Health has coordinated efforts to identify possible cases in travelers to California, USA, from affected areas. During 2013–2014, the department investigated 54 travelers for MERS-CoV; none tested positive, but 32 (62%) of 52 travelers with suspected MERS-CoV had other respiratory viruses. PMID:26291839

  18. The recent ancestry of Middle East respiratory syndrome coronavirus in Korea has been shaped by recombination

    PubMed Central

    Kim, Jin Il; Kim, You-Jin; Lemey, Philippe; Lee, Ilseob; Park, Sehee; Bae, Joon-Yong; Kim, Donghwan; Kim, Hyejin; Jang, Seok-Il; Yang, Jeong-Sun; Kim, Hak; Kim, Dae-Won; Nam, Jeong-Gu; Kim, Sung Soon; Kim, Kisoon; Myun Lee, Jae; Song, Man Ki; Song, Daesub; Chang, Jun; Hong, Kee-Jong; Bae, Yong-Soo; Song, Jin-Won; Lee, Joo-Shil; Park, Man-Seong

    2016-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe cases of human respiratory disease. Since 2012, the victims have mainly come from the Middle East countries or sporadically from some other geographical regions seeded by the travelers who visited the Middle East. Such an introduction through travelling led to the emergence of a MERS-CoV outbreak in Korea in May 2015, which caused more than 140 confirmed human cases in less than a month. Using 70 complete genome sequences of MERS-CoV isolates, including the most recent sequences for the Korean and Chinese isolates, we reconstructed the phylogenetic relationships of the complete genome and the individual protein coding regions. The Korean MERS-CoV strain clustered in the previously established Hafr-Al-Batin-1_2013 clade together with two Saudi Arabian and one Chinese strain sampled in 2015. Although these four strains remained monophyletic in the entire protein-coding region, this clade showed different phylogenetic relationships across the genome, indicating a shared unique recombination pattern that is different from previously reported putative recombination strains. Our findings suggest that the recent ancestor of the Korean and its related MERS-CoV strains is characterized by unique mosaic genome pattern that is different from other putative recombinants. PMID:26732651

  19. Climatic change and the history of the Middle East: Did major climatic changes alter the course of Middle Eastern history during the past 5,000 years?

    SciTech Connect

    Issar, A.S.

    1995-07-01

    This article explores the influence of climatic change on history, specifically that of the Middle Eastern regions. The Middle east may provide a unique model and opportunity to assess the impact of climatic change on human evenst. The climatic history of the Middle East varied considerably during the past 10,000 years (after the beginning of the agricultural revolution) and there is a rich archeological and historical record. The author looks at the conventional reasons for upheavels in the region and then superimposes the climatic changes to find another explanation which better fits the archeological and historical facts. 15 refs., 6 figs.

  20. Mediterranean summer climate and the importance of Middle-East Topography

    NASA Astrophysics Data System (ADS)

    Simpson, Isla; Seager, Richard; Shaw, Tiffany; Ting, Mingfang

    2015-04-01

    In summer, the atmospheric circulation over the Mediterranean is characterized by localized intense subsidence and low level northerlies over the central- to eastern portion of the basin. Here, simulations with the Community Atmosphere Model, version 5 are used to investigate the influence of the elevated terrain of North Africa and the Middle East on this summertime circulation. This builds on previous work that recognized a role for North African topography in localizing the Mediterranean subsidence. By flattening the two regions of elevated terrain in the model it is demonstrated that, while they both conspire to produce about 30% of the summertime subsidence, contrary to previous work, the mountains of the Middle-East dominate in this topographic contribution by far. This topography, consisting primarily of the Zagros Mountain range, alters the circulation throughout the depth of the troposphere over the Mediterranean, and further East. The model results suggest that about 20% of the Mediterranean summertime moisture deficit can be attributed to this mountain induced circulation. This topography, therefore, plays an important role in the climate of the Mediterranean and the large scale circulation over the rest of Eurasia during the summer. Further stationary wave modelling reveals that the mountain influence is produced via mechanical forcing of the flow. The greatest influence of the topography occurs when the low level incident flow is easterly, as happens during the summer, primarily due to the presence of condensational heating over Asia. During other seasons, when the low level incident flow is westerly, the influence of Middle-East topography on the Mediterranean is negligible.

  1. Summertime coastal current reversal opposing offshore forcing and local wind near the middle east coast of Korea: Observation and dynamics

    NASA Astrophysics Data System (ADS)

    Park, Jae-Hyoung; Chang, Kyung-Il; Nam, SungHyun

    2016-07-01

    A 6 year long current measurement at a buoy station off the middle east coast of Korea reveals an equatorward reversal of coastal current in summer opposing poleward local wind stress and offshore boundary current. The current reversal extends about 40 km offshore from the coast and is concurrent with warming and freshening of water column. Estimates of the depth-averaged alongshore momentum balance suggest a major balance between the alongshore pressure gradient and the lateral friction. Sources of the pressure gradient for the summertime current reversal are identified as the alongshore buoyancy gradient driven by the wind curl gradient and the prevalence of warmer and lower salinity water in the north. Alongshore pressure gradient and velocity induced by the wind curl gradient are quantified, which yields the observed seasonal current reversal.

  2. 57. LOOKING UP TAILRACE OF PLANE 2 EAST. WATER DISCHARGING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. LOOKING UP TAILRACE OF PLANE 2 EAST. WATER DISCHARGING FROM CULVERT ON LEFT HAD JUST PASSED THROUGH THE FLUME AND POWER HOUSE IN ORDER TO OPERATE THE LIFT MACHINERY. TAILRACE ON RIGHT IS A BYPASS FLUME SO THAT LEVEL OF CANAL BELOW PLANE 2 EAST CAN BE MAINTAINED. - Morris Canal, Phillipsburg, Warren County, NJ

  3. Acheulean technological behaviour in the Middle Pleistocene landscape of Mieso (East-Central Ethiopia).

    PubMed

    de la Torre, Ignacio; Mora, Rafael; Arroyo, Adrian; Benito-Calvo, Alfonso

    2014-11-01

    The Mieso valley is a new paleoanthropological sequence located in East-Central Ethiopia. It contains Middle and Upper Pleistocene deposits with fossil and lithic assemblages in stratified deposits. This paper introduces the Middle Pleistocene archaeological sequence, attributed to the late Acheulean. Low density clusters of artefacts suggest short-term use of the landscape by Acheulean hominins. In Mieso 31, one of the excavated assemblages, refit sets indicate fragmentation of the reduction sequences and enable study of the initial stages of biface manufacture. Mieso 7, also a stratified site, is primarily characterized by a small concentration of standardized cleavers, and portrays another dimension of Acheulean technology, that related to final stages of use and discard of large cutting tools. Available radiometric dates place the Mieso Acheulean around 212 ka (thousands of years) ago, which would make this sequence among the latest evidence of the Acheulean in East Africa, in a time span when the Middle Stone Age is already documented in the region.

  4. 16. EAST ELEVATION OF FLOAT HOUSE AND FISH WATER RELEASE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. EAST ELEVATION OF FLOAT HOUSE AND FISH WATER RELEASE OUTLET. PART OF ENERGY DISSIPATING BAFFLE PIER SYSTEM IS VISIBLE AT LEFT. - Pit 4 Diversion Dam, Pit River west of State Highway 89, Big Bend, Shasta County, CA

  5. Looking east at the boiler water treatment tank located off ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking east at the boiler water treatment tank located off the west wall of the boiler house. - Wheeling-Pittsburgh Steel Corporation, Allenport Works, Boiler House, Route 88 on West bank of Monongahela River, Allenport, Washington County, PA

  6. AERIAL VIEW LOOKING FURTHER SOUTH EAST, VILLAGE CREEK WATER TREATMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    AERIAL VIEW LOOKING FURTHER SOUTH EAST, VILLAGE CREEK WATER TREATMENT PLANT ON RIGHT SIDE, ENSLEY IN BACKGROUND. - Birmingham Southern Railroad Yard, Thirty-fourth Street, Ensley, Jefferson County, AL

  7. 1. East side of lower dam shown with water level ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. East side of lower dam shown with water level dropped. VIEW WEST - Loleta Recreation Area, Lower Dam, 6 miles Southeast of interesection of State Route 24041 & State Route 66, Loleta, Elk County, PA

  8. 2. East side of lower dam shown with water flowing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. East side of lower dam shown with water flowing over dam. VIEW WEST - Loleta Recreation Area, Lower Dam, 6 miles Southeast of interesection of State Route 24041 & State Route 66, Loleta, Elk County, PA

  9. View of east and south (rear) walls, water wheels and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of east and south (rear) walls, water wheels and generators, interior of Childs Powerhouse. Looking southeast - Childs-Irving Hydroelectric Project, Childs System, Childs Powerhouse, Forest Service Road 708/502, Camp Verde, Yavapai County, AZ

  10. 1. VIEW EAST, TANK POND, OIL HOUSE, WATER TOWER, BOILER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW EAST, TANK POND, OIL HOUSE, WATER TOWER, BOILER HOUSE AND ASSEMBLY PLANT WITH MANHATTAN IN BACKGROUND - Ford Motor Company Edgewater Assembly Plant, 309 River Road, Edgewater, Bergen County, NJ

  11. 4. EXTERIOR VIEW LOOKING EAST. WATER IN THE AQUEDUCT CAN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. EXTERIOR VIEW LOOKING EAST. WATER IN THE AQUEDUCT CAN CAN BE DIVERTED AT THE WASTE WEIR TO BE DISCHARGED INTO THE CULVERT IN FOREGROUND. - Old Croton Aqueduct, Northern Waste Weir, Snowden Avenue & Van Wick Street, Ossining, Westchester County, NY

  12. Progressive Development of Groundwater Sources in Dryland Basins with Vague Hydro-geological Information - Methodology and Examples from the Middle East

    NASA Astrophysics Data System (ADS)

    Adar, E. M.; Issar, A. S.

    2012-04-01

    The history of Middle East was influenced by past global climatic changes. Warm periods caused droughts, which brought desertification, migrations and wars. Cold periods were humid and brought abundance and the settling of the deserts' fringes. The forecast based on this correlation is that the present global warming will cause the drying up of the Middle East. Like in the past, the mitigating of this negative impact should be by the utilization of the long-term storage of the groundwater resources. This will involve deep drilling and pumping and modern irrigation methods in the framework of a new policy of "Progressive Development", which will entail the utilization of the up-till-now, undeveloped natural water resources beyond that of present water replenishment. While the utilization of the one-time groundwater reserves is taking place a master long term comprehensive progressive development plan for the Middle East will be prepared. The Progressive Development methodology infers the step by step development of all existing water resources like treated effluents, desalinated brackish groundwater and at the end desalination of seawater. Key words: climate change, desertification, groundwater, irrigation, desalination

  13. The Impact of the SESAME Project on Science and Society in the Middle East

    NASA Astrophysics Data System (ADS)

    Winick, Herman

    2008-04-01

    SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is a UNESCO-sponsored project that is constructing an international research laboratory, closely modeled on CERN, in Jordan (www.sesame.org.jo). Ten Members of the governing Council (Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Jordan, Pakistan, Palestinian Authority, and Turkey) have responsibility for the project, led by Herwig Schopper, Council President since 1999. In late 2008 Chris Llewellyn-Smith will become Council President. SESAME was initiated by a gift from Germany of the decommissioned BESSY I facility. The BESSY I 0.8 GeV injector is now being installed in the recently completed building, funded by Jordan, as components are procured for a new 133 m circumference, 2.5 GeV third-generation storage ring with 12 locations for insertion devices. Beam line equipment has been provided by laboratories in France, UK, and US. Support also comes from EU, IAEA, ICTP, Japan Society for the Promotion of Science, the US Department of Energy and State Department, and laboratories around the world. The broad scientific program includes biomedical, environmental, and archaeological programs particularly relevant to the Middle East. Five scientific workshops and six annual Users' meetings have brought together several hundred scientists from the region, along with researchers from around the world. Training programs have enabled about 100 scientists from the region to work at synchrotron radiation laboratories. These activities have already had significant impact on science and society in the Middle East, for example leading to collaborations between scientists from countries that are not particularly friendly with each other, and to national planning emphasizing synchrotron radiation research. When research starts in 2011 this impact will grow as graduate students are trained in the region in many scientific disciplines, and scientists working abroad are attracted to return.

  14. HIV Surveillance and Epidemic Profile in the Middle East and North Africa

    PubMed Central

    Shawky, Sherine; Soliman, Cherif; Kassak, Kassem M.; Oraby, Doaa; El-Khoury, Danielle; Kabore, Inoussa

    2011-01-01

    Summary HIV infection is the most devastating infection that has emerged in the recent history. The risk of being infected can be associated with both individual’s knowledge and behavior and community vulnerability influenced by cultural norms, laws, politics, and social practices. Despite that the countries in the Middle East and North Africa have succeeded in keeping low the HIV epidemic rates, the number of identified infected cases are increasing. Since the appearance of the first AIDS cases, all the national authorities devoted their efforts to abort the epidemic in its early stages. The rate of new HIV infections across the Middle East and North Africa region are not at an alarming level, but the need for a concerted effort from nation-states and nongovernmental organizations to stem the spread of the virus across the region is vital. Most countries of the region have put in place better information systems to track the HIV epidemic, yet the passive HIV/AIDS reporting remains the cornerstone in the HIV surveillance systems. Several countries still believe that their current strategies are optimal to the HIV status within their territories and that their national strategies are appropriate to their low epidemic status that is not expected to grow. Additionally, these countries fear that establishing an HIV national program to survey risk behaviors may be perceived as an approval of these behaviors that are culturally and religiously unacceptable. This background article aims to summarize the HIV surveillance strategies and epidemic profile in 17 Arab countries in the Middle East and North Africa. The article, also, displays the national surveillance system and the epidemic profile in Egypt and Lebanon as models for the region. This information aims to provide useful insights that may help the national authorities in finding out the best surveillance strategies that allow merging and collecting biological and risk data which is an integral part of their

  15. Enhancing research ethics capacity in the Middle East: experience and challenges of a Fogarty-sponsored training program.

    PubMed

    Silverman, Henry; Edwards, Hillary; Shamoo, Adil; Matar, Amal

    2013-12-01

    We describe the research ethics capacity needs of the countries from the Middle East region. Against this background, we relate the experience of an international training program focused on providing long-term training in research ethics to individuals from low and middle-income countries in the Middle East area. We describe our pedagogical approach to training, program changes to address challenges faced, and accomplishments of trainees. Many former trainees developed research ethics curricula in their home institutions, established or enhanced their institutions' research ethics committees, provided leadership to national research ethics systems, and conducted research in research ethics. Based on our analysis, we make recommendations for how trainees can further address current regional research ethics needs in the Middle East and conduct future research. This paper is part of a collection of papers analyzing the Fogarty International Center's International Research Ethics Education and Curriculum Development program.

  16. Enhancing Research Ethics Capacity in the Middle East: Experience and Challenges of a Fogarty-Sponsored Training Program

    PubMed Central

    Silverman, Henry; Edwards, Hillary; Shamoo, Adil; Matar, Amal

    2014-01-01

    we describe the research ethics capacity needs of the countries from the Middle East region. Against this background, we relate the experience of an international training program focused on providing long-term training in research ethics to individuals from low- and middle-income countries in the Middle East area. We describe our pedagogical approach to training, program changes to address challenges faced, and accomplishments of trainees. Many former trainees developed research ethics curricula in their home institutions, established or enhanced their institutions’ research ethics committees, provided leadership to national research ethics systems, and conducted research in research ethics. Based on our analysis, we make recommendations for how trainees can further address current regional research ethics needs in the Middle East and conduct future research. This paper is part of a collection of papers analyzing the Fogarty International Center’s International Research Ethics Education and Curriculum Development program. PMID:24384515

  17. Consistent response of Indian summer monsoon to Middle East dust in observations and simulations

    NASA Astrophysics Data System (ADS)

    Jin, Q.; Wei, J.; Yang, Z.-L.; Pu, B.; Huang, J.

    2015-09-01

    The response of the Indian summer monsoon (ISM) circulation and precipitation to Middle East dust aerosols on sub-seasonal timescales is studied using observations and the Weather Research and Forecasting model coupled with online chemistry (WRF-Chem). Satellite data show that the ISM rainfall in coastal southwest India, central and northern India, and Pakistan is closely associated with the Middle East dust aerosols. The physical mechanism behind this dust-ISM rainfall connection is examined through ensemble simulations with and without dust emissions. Each ensemble includes 16 members with various physical and chemical schemes to consider the model uncertainties in parameterizing short-wave radiation, the planetary boundary layer, and aerosol chemical mixing rules. Experiments show that dust aerosols increase rainfall by about 0.44 mm day-1 (~10 % of the climatology) in coastal southwest India, central and northern India, and north Pakistan, a pattern consistent with the observed relationship. The ensemble mean rainfall response over India shows a much stronger spatial correlation with the observed rainfall response than any other ensemble members. The largest modeling uncertainties are from the boundary layer schemes, followed by short-wave radiation schemes. In WRF-Chem, the dust aerosol optical depth (AOD) over the Middle East shows the strongest correlation with the ISM rainfall response when dust AOD leads rainfall response by about 11 days. Further analyses show that increased ISM rainfall is related to enhanced southwesterly monsoon flow and moisture transport from the Arabian Sea to the Indian subcontinent, which are associated with the development of an anomalous low-pressure system over the Arabian Sea, the southern Arabian Peninsula, and the Iranian Plateau due to dust-induced heating in the troposphere. The dust-induced heating in the mid-upper troposphere is mainly located in the Iranian Plateau rather than the Tibetan Plateau. This study

  18. Evaluation of multispectral middle infrared aircraft images for lithologic mapping the East Tintic Mountains, Utah( USA).

    USGS Publications Warehouse

    Kahle, A.B.; Rowan, L.C.

    1980-01-01

    Six channels of moultispectral middle infrared (8 to 14 micrometres) aircraft scanner data were acquired over the East Tintic mining district, Utah. The digital image data were computer processed to create a color-composite image based on principal component transformations. When combined with a visible and near infrared color-composite image from a previous flight, with limited field checking, it is possible to discriminate quartzite, carbonate rocks, quartz latitic and quartz monzonitic rocks, latitic and monzonitic rocks, silicified altered rocks, argillized altered rocks, and vegetation. -from Authors

  19. NMR assignments of the macro domain from Middle East respiratory syndrome coronavirus (MERS-CoV).

    PubMed

    Huang, Yi-Ping; Cho, Chao-Cheng; Chang, Chi-Fon; Hsu, Chun-Hua

    2016-10-01

    The newly emerging human pathogen, Middle East respiratory syndrome coronavirus (MERS-CoV), contains a macro domain in the highly conserved N-terminal region of non-structural protein 3. Intense research has shown that macro domains bind ADP-ribose and other derivatives, but it still remains intangible about their exact function. In this study we report the preliminary structural analysis through solution NMR spectroscopy of the MERS-CoV macro domain. The near complete NMR assignments of MERS-CoV macro domain provide the basis for subsequent structural and biochemical investigation in the context of protein function.

  20. Newcastle disease in captive falcons in the Middle East: a review of clinical and pathologic findings.

    PubMed

    Samour, Jaime

    2014-03-01

    Newcastle disease is an important viral disease of falcons in the Middle East. Two different clinical presentations producing distinct clinical symptoms and pathologic lesions have been identified in affected falcons, denoted as neurotropic velogenic and viscerotropic velogenic forms. Humoral response after vaccination with commercially available oil-emulsion inactivated poultry vaccines has been observed for up to 9 months in vaccinated falcons. Public awareness programs at falcon medical facilities in the region are needed to promote annual vaccinations to prevent Newcastle disease in falcons.

  1. World Directory of Energy Information. Volume 2: Middle East, Africa and Asia/Pacific

    SciTech Connect

    Not Available

    1982-01-01

    Volume 2 of the four-part Directory includes a detailed review of energy resource development of 64 countries, 15 of which are in the Middle East, 30 in Africa, and 19 in the Asia and Pacific area. The volume is divided into four parts: (1) International Framework; (2) Country Reviews; (3) Energy Organizations; and (4) Energy Publications. The organizations and publications information covers both international and by country. Three indices list publications alphabetically, by subject and country, and publishing bodies. 6 figures, 2 tables. (DCK)

  2. Emergency cesarean section in an epidemic of the middle east respiratory syndrome: a case report

    PubMed Central

    Kim, Hee Ryun; Sung, Ji Hee; Kim, Jong Hwa

    2016-01-01

    Only a few reports have been published on women with an infectious respiratory viral pathogen, such as Middle East Respiratory Syndrome (MERS) Coronavirus delivering a baby. A laboratory confirmed case of MERS was reported during a MERS outbreak in the Republic of Korea in a woman at gestational week 35 + 4. She recovered, and delivered a healthy baby by emergency cesarean section (C-sec). We present the clinical course and the emergency C-sec in a pregnant woman with MERS. PMID:27274377

  3. Virtual communities? The Middle East revolutions at the Guardian forum: Comment Is Free

    NASA Astrophysics Data System (ADS)

    Kujawski, B.; Abell, P.

    2011-10-01

    We investigate the possibility of virtual community formation in an online social network under a rapid increase of activity of members and newcomers. The evolution is studied of the activity of online users at the Guardian - Comment Is Free forum - covering topics related to the Middle East turmoil during the period of 1st of January 2010 to the 28th of March 2011. Despite a threefold upsurge of forum users and the formation of a giant component, the main network characteristics, i.e. degree and weight distribution and clustering coefficient, remained almost unchanged.

  4. Saudi demand for Filipino workers: labor migration issues in the Middle East.

    PubMed

    Smart, J E

    1982-08-01

    The increased demand for Filipino workers in Saudi Arabia over the past decade is analyzed. The role of the Philippines in the supply of foreign labor is briefly considered. An overview of manpower needs in the Middle East is presented, and the effects of various social, political, and economic features of Saudi Arabian development on the demand for Filipino workers are examined. Issues discussed include the long-term American presence in Saudi Arabia, sensitivity to the impact of foreigners on the work force and on life-style, investment in the welfare of temporary workers, skill requirements, wages and productivity, and political influence.

  5. Enhanced surveillance for detection and management of infectious diseases: regional collaboration in the middle East.

    PubMed

    Leventhal, Alex; Ramlawi, Assad; Belbiesi, Adel; Sheikh, Sami; Haddadin, Akhtam; Husseini, Sari; Abdeen, Ziad; Cohen, Dani

    2013-01-01

    Formed before international negotiations of the revised International Health Regulations (IHR), the Middle East Consortium for Infectious Disease Surveillance (MECIDS) is a regional collaboration aimed at facilitating implementation of the revised IHR and, more broadly, improving the detection and control of infectious disease outbreaks among neighboring countries in an area of continuous dispute. Initially focused on enhancing foodborne disease surveillance, MECIDS has expanded the scope of its work to also include avian and pandemic influenza and other emerging and re-emerging infectious diseases. Here, we describe the history and governance of MECIDS, highlighting key achievements over the consortium's seven-year history, and discuss the future of MECIDS. PMID:23362413

  6. Genetic diversity analysis of wild close relatives of barley from Tibet and the Middle East by ISSR and SSR markers.

    PubMed

    Wang, Aihua; Yu, Zhiyong; Ding, Yi

    2009-04-01

    The genetic diversity analysis of 90 barley samples, including 45 wild close relatives of barley from the Tibet region of China and 45 wild accessions from different countries throughout the Middle East, were carried out using ISSR and SSR markers. The results showed that Tibetan wild close relatives of barley had a higher genetic diversity than those from the Middle East. Ten ISSR primers amplified 91 allelic variants, of which 79 were polymorphic (86.81%), in the Tibetan genotypes and 82 allelic variants, of which 66 were polymorphic (80.49%), in the Middle East genotypes. Eleven primer pairs of SSR markers amplified 100 allelic variants among the Tibetan genotypes with 100 polymorphic bands (100%). Among the Middle East genotypes, 78 allelic variants were produced containing 77 polymorphic bands (98.72%). Moreover, the total gene diversity analysis (HT) values of Tibetan barley (0.227 for ISSRs and 0.126 for SSRs) were higher than those of Middle East (0.212 for ISSRs and 0.102 for SSRs). Cluster analysis of the ISSR and SSR results by the UPGMA method revealed two distinct groups correlated with the geographic origin of sampling. These results offer a new evidence for the theory of the origin of Hordeum vulgare L. PMID:19304270

  7. Study of Regional Volcanic Impact on the Middle East and North Africa using high-resolution global and regional models

    NASA Astrophysics Data System (ADS)

    Osipov, Sergey; Dogar, Mohammad; Stenchikov, Georgiy

    2016-04-01

    High-latitude winter warming after strong equatorial volcanic eruptions caused by circulation changes associated with the anomalously positive phase of Arctic Oscillation is a subject of active research during recent decade. But severe winter cooling in the Middle East observed after the Mt. Pinatubo eruption of 1991, although recognized, was not thoroughly investigated. These severe regional climate perturbations in the Middle East cannot be explained by solely radiative volcanic cooling, which suggests that a contribution of forced circulation changes could be important and significant. To better understand the mechanisms of the Middle East climate response and evaluate the contributions of dynamic and radiative effects we conducted a comparative study using Geophysical Fluid Dynamics Laboratory global High Resolution Atmospheric Model (HiRAM) with the effectively "regional-model-resolution" of 25-km and the regional Weather Research and Forecasting (WRF) model focusing on the eruption of Mount Pinatubo on June 15, 1991 followed by a pronounced positive phase of the Arctic Oscillation. The WRF model has been configured over the Middle East and North Africa (MENA) region. The WRF code has been modified to interactively account for the radiative effect of volcanic aerosols. Both HiRAM and WRF capture the main features of the MENA climate response and show that in winter the dynamic effects in the Middle East prevail the direct radiative cooling from volcanic aerosols.

  8. Clinical Assessment and Management of Spondyloarthritides in the Middle East: A Multinational Investigation

    PubMed Central

    Hammoudeh, Mohammed; Al Rayes, Hanan; Gado, Kamel; Shirazy, Khalid; Deodhar, Atul

    2015-01-01

    Data on spondyloarthritis (SpA) from the Middle East are sparse and the management of these diseases in this area of the world faces a number of challenges, including the relevant resources to enable early diagnosis and referral and sufficient funds to aid the most appropriate treatment strategy. The objective was to report on the characteristics, disease burden, and treatment of SpA in the Middle East region and to highlight where management strategies could be improved, with the overall aim of achieving better patient outcomes. This multicenter, observational, cross-sectional study collected demographic, clinical, laboratory, and treatment data on 169 consecutive SpA patients at four centers (Egypt, Kuwait, Qatar, and Saudi Arabia). The data collected presents the average time from symptom onset to diagnosis along with the presence of comorbidities in the region and comparisons between treatment with NSAIDs and biologics. In the absence of regional registries of SpA patients, the data presented here provide a rare snapshot of the characteristics, disease burden, and treatment of these patients, highlighting the management challenges in the region. PMID:26793241

  9. Helicobacter pylori and gastric cancer in the Middle East: a new enigma?

    PubMed

    Hussein, Nawfal R

    2010-07-14

    The Middle East is the home of ethnic groups from three main backgrounds: Semitic (Arabs and Jews), Indo-European (Persians and Kurdish) and Turkic (Turkish and Turkmens). Its geographic location, which has been under continuous influences from Asia, Europe and Africa, has made it an ideal site for epidemiological studies on Helicobacter pylori (H. pylori) infection and genotyping. The gastric cancer rate differs in this region from very high in Iran (26.1/10(5)) to low in Israel (12.5/10(5)) and very low in Egypt (3.4/10(5)). Epidemiological studies showed that the prevalence of H. pylori is almost similar in those countries with a high level of infection in childhood. Importantly, the frequency of vacA s1 and m1 regions and cagA+ genotypes were higher in non Semitic populations who inhabit the North than Semitic populations, the inhabitants of Southern parts of the Middle East. H. pylori infection prevalence, distribution pattern of virulence factors, diet and smoking could not have explained the difference in cancer rate. This reflects the multifactorial aetiology of gastric cancer and suggests that H. pylori infection does not always directly correlate with the risk for gastrointestinal disease, such as gastric cancer. Further detailed investigations and international comparative studies of each risk factor need to be performed to investigate whether this represents a true enigma. PMID:20614477

  10. Middle East respiratory syndrome coronavirus antibody reactors among camels in Dubai, United Arab Emirates, in 2005.

    PubMed

    Alexandersen, S; Kobinger, G P; Soule, G; Wernery, U

    2014-04-01

    We tested, using a low starting dilution, sequential serum samples from dromedary camels, sheep and horses collected in Dubai from February/April to October of 2005 and from dromedary camels for export/import testing between Canada and USA in 2000-2001. Using a standard Middle East respiratory syndrome coronavirus (MERS-CoV) neutralization test, serial sera from three sheep and three horses were all negative while sera from 9 of 11 dromedary camels from Dubai were positive for antibodies supported by similar results in a MERS-CoV recombinant partial spike protein antibody ELISA. The two negative Dubai camels were both dromedary calves and remained negative over the 5 months studied. The six dromedary samples from USA and Canada were negative in both tests. These results support the recent findings that infection with MERS-CoV or a closely related virus is not a new occurrence in camels in the Middle East. Therefore, interactions of MERS-CoV at the human-animal interface may have been ongoing for several, perhaps many, years and by inference, a widespread pandemic may be less likely unless significant evolution of the virus allow accelerated infection and spread potential in the human population.

  11. Super-giant oil fields and future prospects in the Middle East

    SciTech Connect

    Christian, L.; Johnston, D.

    1995-06-01

    Upper Jurassic carbonates, Lower Cretaceous sands, Lower Cretaceous carbonates and Tertiary carbonates of the Middle East contain more than 50% of the worlds oil. Our area of interest covers SE Turkey and Syria in the north to the borders of Yemen and Oman in the south, and from the Red Sea across Saudi Arabia, the Emirates and the Arabian/Persian Gulf to Iran in the East. There are over 80 fields in this region with over 1 billion barrels of recoverable reserves. Yet only around 30,000 wells have been drilled in this territory. Regional structure and stratigraphy are discussed within the context of three major plays in the region as well as a new play in the Permo-Carboniferous. Numerous opportunities are available and countries such as Iraq and Iran may one day open their doors more to the industry than is presently the case. The dramatic petroleum geology of the region will stamp its influence on the nature of business and opportunities for years to come. While fiscal systems here already offer some of the toughest terms in the world, future deals in the more prolific areas will be even tougher. But, the economies of Middle Eastern scale will provide some of the great mega-opportunities of future international exploration.

  12. Middle East measurements of concentration and size distribution of aerosol particles for coastal zones

    NASA Astrophysics Data System (ADS)

    Bendersky, Sergey; Kopeika, Norman S.; Blaunstein, Natan S.

    2005-10-01

    Recently, an extension of the Navy Aerosol Model (NAM) was proposed based on analysis of an extensive series of measurements at the Irish Atlantic Coast and at the French Mediterranean Coast. We confirm the relevance of that work for the distant eastern Meditteranean and extend several coefficients of that coastal model, proposed by Piazzola et al. for the Meditteranean Coast (a form of the Navy Aerosol Model), to midland Middle East coastal environments. This analysis is based on data collected at three different Middle East coastal areas: the Negev Desert (Eilat) Red Sea Coast, the Sea of Galilee (Tiberias) Coast, and the Mediterranean (Haifa) Coast. Aerosol size distributions are compared with those obtained through measurements carried out over the Atlantic, Pacific, and Indian Ocean Coasts, and Mediterranean, and Baltic Seas Coasts. An analysis of these different results allows better understanding of the similarities and differences between different coastal lake, sea, and open ocean zones. It is shown that in the coastal regions in Israel, compared to open ocean and other sea zones, larger differences in aerosol particle concentration are observed. The aerosol particle concentrations and their dependences on wind speed for these coastal zones are analyzed and discussed. We propose to classify the aerosol distribution models to either: 1. a coastal model with marine aerosol domination; 2. a coastal model with continental aerosol domination (referred to as midland coast in this work); or 3. a coastal model with balanced marine and continental conditions.

  13. Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control

    PubMed Central

    Durai, Prasannavenkatesh; Batool, Maria; Shah, Masaud; Choi, Sangdun

    2015-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) causes high fever, cough, acute respiratory tract infection and multiorgan dysfunction that may eventually lead to the death of the infected individuals. MERS-CoV is thought to be transmitted to humans through dromedary camels. The occurrence of the virus was first reported in the Middle East and it subsequently spread to several parts of the world. Since 2012, about 1368 infections, including ~487 deaths, have been reported worldwide. Notably, the recent human-to-human ‘superspreading' of MERS-CoV in hospitals in South Korea has raised a major global health concern. The fatality rate in MERS-CoV infection is four times higher compared with that of the closely related severe acute respiratory syndrome coronavirus infection. Currently, no drug has been clinically approved to control MERS-CoV infection. In this study, we highlight the potential drug targets that can be used to develop anti-MERS-CoV therapeutics. PMID:26315600

  14. Return migration and occupational change: the case of Pakistani migrants returned from the Middle East.

    PubMed

    Arif, G M; Irfan, M

    1997-01-01

    This paper reports on the factors affecting occupational composition of Pakistani workers upon their return from Middle East employment locations as determined by using the 1986 ILO/ARTEP Survey of Return Migrant Households. Three issues related to post-migration occupation change of return migrants were explored: 1) the comparison of occupational composition in the pre-migration phase with the composition during migration; 2) the direction of occupational change; and 3) the factors affecting these changes after return. 44% of the total employed in the ILO sample changed their pre-migration occupations upon return from employment in production or service jobs to smallbusinessrelated employment; the highest level of occupational change was observed in nonirrigated areas. Occupational change was strongly related to migrants' duration of stay in the Middle East, their ages upon returning, and their level of educational attainment. Occupational mobility experienced by the returnees was mainly towards the business sectora direction approved by the Pakistan Government. The preference of the returnees to work independently might have enabled them to earn sufficient money to maintain their higher standard of living into the period following return migration. It is concluded that in order to achieve stability in the businesses established by the returnees, the Overseas Pakistanis' Foundation should provide services, including project-oriented training courses and loan plans, that will aid the returnees in managing their small businesses.

  15. The pursuit of longevity - the bringer of peace to the middle East.

    PubMed

    Stambler, Ilia

    2014-01-01

    Despite the common apprehensions regarding the aging population, this work aims to argue, on both deontological and utilitarian moral grounds, that any increase in general life-expectancy will be beneficial for the Middle East, countering the common fears associated with this increase. A set of ethical arguments concerning increasing longevity is presented, from both the deontological and utilitarian perspective. A wide selection of economic, psychological, demographic and epidemiological literature and databases is analyzed to determine common correlates of extended longevity. On the deontological grounds, the value of extended longevity is derived from the value of life preservation, regardless of its term. On the utilitarian grounds, the value of extended longevity is demonstrated by its correlation with further human values, such as education level and intellectual activity, economic prosperity, equality, solidarity and peacefulness. With the common apprehensions of stagnation and scarcity due to life extension found wanting, the pursuit of longevity by the population can be seen as a cross-cultural and cross-generational good. Though the current study mainly refers to sources and data relevant to the Middle East, a similar pro-longevity argument can be also made for other cultural contexts. In view of its numerous benefits, normatively, the goal of longevity should be set clearly and openly by the society, and actively pursued, or at least discussed, in academia, the political system and broader public. PMID:24852012

  16. Middle East respiratory syndrome coronavirus "MERS-CoV": current knowledge gaps.

    PubMed

    Banik, G R; Khandaker, G; Rashid, H

    2015-06-01

    The Middle East respiratory syndrome coronavirus (MERS-CoV) that causes a severe lower respiratory tract infection in humans is now considered a pandemic threat to the Gulf region. Since its discovery in 2012, MERS-CoV has reached 23 countries affecting about 1100 people, including a dozen children, and claiming over 400 lives. Compared to SARS (severe acute respiratory syndrome), MERS-CoV appears to kill more people (40% versus 10%), more quickly, and is especially more severe in those with pre-existing medical conditions. Most MERS-CoV cases (>85%) reported thus far have a history of residence in, or travel to the Middle East. The current epidemiology is characterised by slow and sustained transmission with occasional sparks. The dromedary camel is the intermediate host of MERS-CoV, but the transmission cycle is not fully understood. In this current review, we have briefly summarised the latest information on the epidemiology, clinical features, diagnosis, treatment and prevention of MERS-CoV especially highlighting the knowledge gaps in its transmission dynamics, diagnosis and preventive strategy. PMID:26002405

  17. The pursuit of longevity - the bringer of peace to the middle East.

    PubMed

    Stambler, Ilia

    2014-01-01

    Despite the common apprehensions regarding the aging population, this work aims to argue, on both deontological and utilitarian moral grounds, that any increase in general life-expectancy will be beneficial for the Middle East, countering the common fears associated with this increase. A set of ethical arguments concerning increasing longevity is presented, from both the deontological and utilitarian perspective. A wide selection of economic, psychological, demographic and epidemiological literature and databases is analyzed to determine common correlates of extended longevity. On the deontological grounds, the value of extended longevity is derived from the value of life preservation, regardless of its term. On the utilitarian grounds, the value of extended longevity is demonstrated by its correlation with further human values, such as education level and intellectual activity, economic prosperity, equality, solidarity and peacefulness. With the common apprehensions of stagnation and scarcity due to life extension found wanting, the pursuit of longevity by the population can be seen as a cross-cultural and cross-generational good. Though the current study mainly refers to sources and data relevant to the Middle East, a similar pro-longevity argument can be also made for other cultural contexts. In view of its numerous benefits, normatively, the goal of longevity should be set clearly and openly by the society, and actively pursued, or at least discussed, in academia, the political system and broader public.

  18. Modeling the Transmission of Middle East Respirator Syndrome Corona Virus in the Republic of Korea

    PubMed Central

    Xia, Zhi-Qiang; Zhang, Juan; Xue, Ya-Kui; Sun, Gui-Quan; Jin, Zhen

    2015-01-01

    The 2015 epidemic of Middle East respiratory syndrome (MERS) in the Republic of Korea has been the largest outbreak outside Middle East. This epidemic had caused 185 laboratory-confirmed cases and 36 deaths in the Republic of Korea until September 2, 2015, which attracted public’s attention. Based on the detailed data of patients released by World Health Organization (WHO) and actual propagation of the epidemic, we construct two dynamical models to simulate the propagation processes from May 20 to June 8 and from June 9 to July 10, 2015, respectively and find that the basic reproduction number R0 reaches up to 4.422. The numerical analysis shows that the reasons of the outbreak spread quickly are lack of self-protection sense and targeted control measures. Through partial correction analysis, the parameters β1 and γ have strong correlations with R0, i.e., the infectivity and proportion of the asymptomatic infected cases have much influence on the spread of disease. By sensitivity analysis, strengthening self-protection ability of susceptible and quickly isolating or monitoring close contacts are effective measures to control the disease. PMID:26690750

  19. Helicobacter pylori and gastric cancer in the Middle East: A new enigma?

    PubMed Central

    Hussein, Nawfal R

    2010-01-01

    The Middle East is the home of ethnic groups from three main backgrounds: Semitic (Arabs and Jews), Indo-European (Persians and Kurdish) and Turkic (Turkish and Turkmens). Its geographic location, which has been under continuous influences from Asia, Europe and Africa, has made it an ideal site for epidemiological studies on Helicobacter pylori (H. pylori) infection and genotyping. The gastric cancer rate differs in this region from very high in Iran (26.1/105) to low in Israel (12.5/105) and very low in Egypt (3.4/105). Epidemiological studies showed that the prevalence of H. pylori is almost similar in those countries with a high level of infection in childhood. Importantly, the frequency of vacA s1 and m1 regions and cagA+ genotypes were higher in non Semitic populations who inhabit the North than Semitic populations, the inhabitants of Southern parts of the Middle East. H. pylori infection prevalence, distribution pattern of virulence factors, diet and smoking could not have explained the difference in cancer rate. This reflects the multifactorial aetiology of gastric cancer and suggests that H. pylori infection does not always directly correlate with the risk for gastrointestinal disease, such as gastric cancer. Further detailed investigations and international comparative studies of each risk factor need to be performed to investigate whether this represents a true enigma. PMID:20614477

  20. General view of Sector Six Compound, looking east. Water Storage ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of Sector Six Compound, looking east. Water Storage Tank is at left - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Water Storage Plant, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  1. Revolutionising engineering education in the Middle East region to promote earthquake-disaster mitigation

    NASA Astrophysics Data System (ADS)

    Baytiyeh, Hoda; Naja, Mohamad K.

    2014-09-01

    Due to the high market demands for professional engineers in the Arab oil-producing countries, the appetite of Middle Eastern students for high-paying jobs and challenging careers in engineering has sharply increased. As a result, engineering programmes are providing opportunities for more students to enrol on engineering courses through lenient admission policies that do not compromise academic standards. This strategy has generated an influx of students who must be carefully educated to enhance their professional knowledge and social capital to assist in future earthquake-disaster risk-reduction efforts. However, the majority of Middle Eastern engineering students are unaware of the valuable acquired engineering skills and knowledge in building the resilience of their communities to earthquake disasters. As the majority of the countries in the Middle East are exposed to seismic hazards and are vulnerable to destructive earthquakes, engineers have become indispensable assets and the first line of defence against earthquake threats. This article highlights the contributions of some of the engineering innovations in advancing technologies and techniques for effective disaster mitigation and it calls for the incorporation of earthquake-disaster-mitigation education into academic engineering programmes in the Eastern Mediterranean region.

  2. New records of predaceous midges from the Middle East, with the description of two new species (Diptera: Ceratopogonidae).

    PubMed

    Dominiak, Patrycja; Alwin, Alicja; Giłka, Wojciech

    2014-01-01

    Two new distinctive species of predaceous biting midges of the tribe Ceratopogonini are described and illustrated from the Middle East. Brachypogon freidbergi sp. nov., with a unique Y-shaped gonostylus, is recorded from Israel. We also provide the first records of Brachypogon vitiosus (Winnertz) and B. aethiopicus (Clastrier, Rioux & Descous) from this country, and a key to the adult males of the genus Brachypogon Kieffer from the Middle East. Ceratopogon azari sp. nov., described from Lebanon, shows a distinctive structure of the male genital apparatus, and is the southernmost species of that genus in the Western Palaearctic. PMID:24872285

  3. Blood vitamins and trace elements in Northern-East African cheetahs (Acinonyx jubatus soemmeringii) in captivity in the Middle East.

    PubMed

    Beckmann, Katie M; O'Donovan, Declan; McKeown, Sean; Wernery, Ulli; Basu, Puja; Bailey, Tom A

    2013-09-01

    There are few published data regarding the endangered Northern-East African cheetah (Acinonyx jubatus soemmeringii), held in captivity in the Middle East and Europe. Studies have demonstrated a high incidence of disease in captive cheetahs, in which vitamin and trace element imbalances have often been implicated. Blood vitamin and trace element reference values in cheetahs merit further investigation. In this study, blood samples were opportunistically collected from apparently healthy A. j. soemmeringii from two collections (A and B) with successful breeding programs in the United Arab Emirates. The cheetahs were fed whole prey of mixed species (and, in Collection B, goat muscle and bone as well) dusted with vitamin and mineral supplements. Mean serum vitamin and trace element values (for cheetahs > 4 mo in age) were as follows: vitamin A (retinol), 2.20 microM/L (n = 27); vitamin B1, 0.0818 microM/L (n = 45); vitamin C, 28.6 microM/L (n=10); vitamin E (alpha-tocopherol), 35.6 microM/L (n = 27); copper (Cu), 12.53 microM/L (n = 27); selenium (Se), 3.10 microM/L (n = 27); and zinc (Zn), 10.87 microM/L (n = 27). Mean values of vitamin A, vitamin E, Cu, and Zn fell within ranges of published cheetah mean values, and mean Se was lower than range values for cheetahs presented in one previous study; blood vitamin B1 and vitamin C values of cheetahs have not previously been published. The values were taken to indicate that the cheetahs' nutritional status was adequate with regard to those nutrients analyzed. Serum vitamin E was particularly high in cheetahs fed fresh whole prey, and on this basis vitamin E supplementation of fresh whole prey appeared to have been unnecessary. There were differences (P < 0.05) between collections in serum vitamin B1, vitamin E, Cu, and 10 other hematologic and biochemical parameters. Nine hematologic and blood biochemical parameters differed among age categories.

  4. SESAME - A 3rd Generation Synchrotron Light Source for the Middle East

    SciTech Connect

    Ulkue, Dincer; Rahighi, Javad; Winick, Herman

    2007-01-19

    SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be the Middle East's first international research center. It is a cooperative venture by the scientists and governments of the region with founding members Bahrain, Egypt, Israel, Jordan, Pakistan, Palestine Authority, and Turkey. Iran is in the process of finalizing its formal membership. Other countries (Cyprus, Morocco, and the United Arab Emirates) are also expected to join. The permanent Council of member states has full responsibility for the project. Members provide the annual operating budget. Observer countries are Germany, Greece, Italy, Kuwait, Portugal, Russian Federation, Sweden, the UK, and the US. SESAME is being developed under the umbrella of UNESCO. Jordan was selected as the building site. SESAME will offer excellent opportunities for training of Middle East scientists and attract those working abroad to consider returning. SESAME will be a 2.5GeV 3rd Generation light source (emittance 26nm-rad, circumference {approx}133m), providing excellent performance for structural molecular biology, molecular environmental science, surface and interface science, microelectromechanical devices, x-ray imaging, archaeological microanalysis, and materials characterization. It will cover a broad spectral range from the infrared to hard x-rays and will have 12 straight sections for insertion devices (average length 2.75m). The injector will be the BESSY I 0.8 GeV booster synchrotron which has been given as a gift from Germany. Four committees advise the Council and assist in developing the technical design, beam lines, user community, and scientific Program. The SESAME building, now in construction with funds and a site provided by Jordan, is scheduled for completion in late 2006 after which the BESSY I injector will be installed. First stored beam in the new 2.5 GeV ring is planned for 2009 with six initial beamlines planned. Some beamlines will be built by member

  5. Water resources of East Baton Rouge Parish, Louisiana

    USGS Publications Warehouse

    White, Vincent E.; Prakken, Lawrence B.

    2015-01-01

    Information concerning the availability, use, and quality of water in East Baton Rouge Parish, Louisiana, is critical for proper water-supply management. The purpose of this fact sheet is to present information that can be used by water managers, parish residents, and others for stewardship of this vital resource. Information on the availability, past and current use, use trends, and water quality from groundwater and surface-water sources in the parish is presented. Previously published reports and data stored in the U.S. Geological Survey’s National Water Information System (http://waterdata.usgs.gov/nwis) are the primary sources of the information presented here.

  6. Workers' remittances from the Middle East and their effect on Pakistan's economy.

    PubMed

    Burney, N A

    1987-01-01

    "This paper makes an attempt to analyse the impact of remittances on the Pakistani economy, in particular, on broad economic indicators [such] as GNP growth, saving, and balance of payments (BOP), from 1969-70 to 1985-86. Section II estimates the contribution of the remittances, from the Middle East, to the growth in the Gross National Product (GNP), over different sub-periods. In Section III, an analysis of the relationship between national/domestic savings and remittances is given. Section IV discusses the impact of remittances on the balance of payments position of Pakistan. Finally, the main findings are summarized in Section V." Comments by Meekal A. Ahmad are included (pp. 762-3). PMID:12342015

  7. Middle East Respiratory Syndrome Coronavirus Superspreading Event Involving 81 Persons, Korea 2015.

    PubMed

    Oh, Myoung-don; Choe, Pyoeng Gyun; Oh, Hong Sang; Park, Wan Beom; Lee, Sang-Min; Park, Jinkyeong; Lee, Sang Kook; Song, Jeong-Sup; Kim, Nam Joong

    2015-11-01

    Since the first imported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection was reported on May 20, 2015 in Korea, there have been 186 laboratory-confirmed cases of MERS-CoV infection with 36 fatalities. Ninety-seven percent (181/186) of the cases had exposure to the health care facilities. We are reporting a superspreading event that transmitted MERS-CoV to 81 persons at a hospital emergency room (ER) during the Korean outbreak in 2015. The index case was a 35-yr-old man who had vigorous coughing while staying at the ER for 58 hr. As in severe acute respiratory syndrome outbreaks, superspreading events can cause a large outbreak of MERS in healthcare facilities with severe consequences. All healthcare facilities should establish and implement infection prevention and control measure as well as triage policies and procedures for early detection and isolation of suspected MERS-CoV cases.

  8. Conservation of nucleotide sequences for molecular diagnosis of Middle East respiratory syndrome coronavirus, 2015.

    PubMed

    Furuse, Yuki; Okamoto, Michiko; Oshitani, Hitoshi

    2015-11-01

    Infection due to the Middle East respiratory syndrome coronavirus (MERS-CoV) is widespread. The present study was performed to assess the protocols used for the molecular diagnosis of MERS-CoV by analyzing the nucleotide sequences of viruses detected between 2012 and 2015, including sequences from the large outbreak in eastern Asia in 2015. Although the diagnostic protocols were established only 2 years ago, mismatches between the sequences of primers/probes and viruses were found for several of the assays. Such mismatches could lead to a lower sensitivity of the assay, thereby leading to false-negative diagnosis. A slight modification in the primer design is suggested. Protocols for the molecular diagnosis of viral infections should be reviewed regularly after they are established, particularly for viruses that pose a great threat to public health such as MERS-CoV.

  9. Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014

    PubMed Central

    Alraddadi, Basem M.; Watson, John T.; Almarashi, Abdulatif; Abedi, Glen R.; Turkistani, Amal; Sadran, Musallam; Housa, Abeer; Almazroa, Mohammad A.; Alraihan, Naif; Banjar, Ayman; Albalawi, Eman; Alhindi, Hanan; Choudhry, Abdul Jamil; Meiman, Jonathan G.; Paczkowski, Magdalena; Curns, Aaron; Mounts, Anthony; Feikin, Daniel R.; Marano, Nina; Swerdlow, David L.; Gerber, Susan I.; Hajjeh, Rana

    2016-01-01

    Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March–November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a case–control design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2–4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV. PMID:26692185

  10. Verification of ECMWF, GFS and WRF forecast in coastal desert region of Middle East

    NASA Astrophysics Data System (ADS)

    Nechaj, Pavol; Bartoková, Ivana

    2014-05-01

    Forecast skill of different models over Middle East region is presented. ECMWF has 12.5 km resolution, while WRF with 16 km and nested 5 km grid is initialized by GFS. The comparison encompasses first half of year 2012 and 48-72 hours forecasts, which are evaluated by standard scores Bias, Mean Absolute Error (MAE) and Root Mean Square Error (RMSE). In Dubai Emirate, the temperature RMSE of ECMWF is higher by 1.5 deg. C on average. As far as the desert terrain is flat and the station is 100km form the coast, the reason is not straightforward result of better resolution. More precise capturing of the diurnal variation especially the sea breeze phenomenon seems of higher importance. 9 other stations were examined.

  11. Family patterns, women's status and fertility in the Middle East and North Africa.

    PubMed

    Allman, J

    1978-01-01

    Currently, countries in the Middle East and North Africa are in the process of changing from high to low mortality and fertility, and the present paper reviews and assesses the current state of the social science research on family patterns and women's status in these regions. In particular, it reviews literature on: 1) marriage patterns; 2) the extended family and relations internal to the family; 3) larger kinship structures; 4) the role and status of women in the larger society; and 5) divorce, widowhood, and remarriage. The author, however, believes that much of the research on family patterns lacks concern with the impact of basic structural changes in the economic and social organization of countries in the region. He concludes by offering a few suggestions about areas where research linking population dynamics with family patterns and the status of women could be usefully undertaken.

  12. Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants

    PubMed Central

    Borucki, Monica K.; Lao, Victoria; Hwang, Mona; Gardner, Shea; Adney, Danielle; Munster, Vincent; Bowen, Richard; Allen, Jonathan E.

    2016-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging human pathogen related to SARS virus. In vitro studies indicate this virus may have a broad host range suggesting an increased pandemic potential. Genetic and epidemiological evidence indicate camels serve as a reservoir for MERS virus but the mechanism of cross species transmission is unclear and many questions remain regarding the susceptibility of humans to infection. Deep sequencing data was obtained from the nasal samples of three camels that had been experimentally infected with a human MERS-CoV isolate. A majority of the genome was covered and average coverage was greater than 12,000x depth. Although only 5 mutations were detected in the consensus sequences, 473 intrahost single nucleotide variants were identified. Many of these variants were present at high frequencies and could potentially influence viral phenotype and the sensitivity of detection assays that target these regions for primer or probe binding. PMID:26790002

  13. Guidelines for the Laboratory Diagnosis of Middle East Respiratory Syndrome Coronavirus in Korea.

    PubMed

    Lee, Hyukmin; Ki, Chang-Seok; Sung, Heungsup; Kim, Sinyoung; Seong, Moon-Woo; Yong, Dongeun; Kim, Jae-Seok; Lee, Mi-Kyung; Kim, Mi-Na; Choi, Jong-Rak; Kim, Jeong-Ho

    2016-03-01

    The recent outbreak of Middle East respiratory syndrome (MERS) in Korea was unexpected that laboratory response had to be built up urgently during the outbreak. The outbreak was almost all healthcare-associated, which was aggravated by lack of availability in laboratory diagnosis of MERS-CoV on site. On behalf of the MERS joint public and private sector response committee (MERS Joint committee), the Korean Society for Laboratory Medicine (KSLM) launched a MERS response task force (MERS KSLM TF) to facilitate clinical laboratories set up MERS molecular diagnosis. MERS TF established guidelines for laboratory diagnosis of MERS-CoV and provided it to all participating laboratories as the official guidance of MERS Joint committee. This guideline was used for procedure manual of molecular diagnosis of MERS-CoV and laboratory safety manual. PMID:27104019

  14. Middle East Respiratory Syndrome Infection Control and Prevention Guideline for Healthcare Facilities

    PubMed Central

    Kim, Jin Yong; Song, Joon Young; Yoon, Young Kyung; Choi, Seong-Ho; Song, Young Goo; Kim, Sung-Ran; Son, Hee-Jung; Jeong, Sun-Young; Choi, Jung-Hwa; Kim, Kyung Mi; Yoon, Hee Jung; Choi, Jun Yong; Kim, Tae Hyong; Choi, Young Hwa; Kim, Hong Bin; Yoon, Ji Hyun; Lee, Jacob; Eom, Joong Sik; Lee, Sang-Oh; Oh, Won Sup; Choi, Jung-Hyun; Yoo, Jin-Hong; Kim, Woo Joo

    2015-01-01

    Middle East Respiratory Syndrome (MERS) is an acute viral respiratory illness with high mortality caused by a new strain of betacoronavirus (MERS-CoV). Since the report of the first patient in Saudi Arabia in 2012, large-scale outbreaks through hospital-acquired infection and inter-hospital transmission have been reported. Most of the patients reported in South Korea were also infected in hospital settings. Therefore, to eliminate the spread of MERS-CoV, infection prevention and control measures should be implemented with rigor. The present guideline has been drafted on the basis of the experiences of infection control in the South Korean hospitals involved in the recent MERS outbreak and on domestic and international infection prevention and control guidelines. To ensure efficient MERS-CoV infection prevention and control, care should be taken to provide comprehensive infection control measures including contact control, hand hygiene, personal protective equipment, disinfection, and environmental cleaning. PMID:26788414

  15. Guidelines for the Laboratory Diagnosis of Middle East Respiratory Syndrome Coronavirus in Korea

    PubMed Central

    Sung, Heungsup; Kim, Sinyoung; Seong, Moon-Woo; Yong, Dongeun; Kim, Jae-Seok; Lee, Mi-Kyung; Choi, Jong-Rak; Kim, Jeong-Ho

    2016-01-01

    The recent outbreak of Middle East respiratory syndrome (MERS) in Korea was unexpected that laboratory response had to be built up urgently during the outbreak. The outbreak was almost all healthcare-associated, which was aggravated by lack of availability in laboratory diagnosis of MERS-CoV on site. On behalf of the MERS joint public and private sector response committee (MERS Joint committee), the Korean Society for Laboratory Medicine (KSLM) launched a MERS response task force (MERS KSLM TF) to facilitate clinical laboratories set up MERS molecular diagnosis. MERS TF established guidelines for laboratory diagnosis of MERS-CoV and provided it to all participating laboratories as the official guidance of MERS Joint committee. This guideline was used for procedure manual of molecular diagnosis of MERS-CoV and laboratory safety manual. PMID:27104019

  16. Comparative SWOT analysis of strategic environmental assessment systems in the Middle East and North Africa region.

    PubMed

    Rachid, G; El Fadel, M

    2013-08-15

    This paper presents a SWOT analysis of SEA systems in the Middle East North Africa region through a comparative examination of the status, application and structure of existing systems based on country-specific legal, institutional and procedural frameworks. The analysis is coupled with the multi-attribute decision making method (MADM) within an analytical framework that involves both performance analysis based on predefined evaluation criteria and countries' self-assessment of their SEA system through open-ended surveys. The results show heterogenous status with a general delayed progress characterized by varied levels of weaknesses embedded in the legal and administrative frameworks and poor integration with the decision making process. Capitalizing on available opportunities, the paper highlights measures to enhance the development and enactment of SEA in the region. PMID:23648267

  17. Religion, spirituality and mental health in the West and the Middle East.

    PubMed

    Koenig, Harold G; Zaben, Faten Al; Khalifa, Doaa Ahmed

    2012-06-01

    Research on religion, spirituality and mental health has been rapidly accumulating from Western countries and now increasingly from the Middle East. We review here the latest research on this topic from these two areas of the world, one largely Christian and the other largely Muslim, after discussing similarities and differences in these faith traditions. Contrary to popular thought, there is considerable overlap between these religious groups in beliefs, practices of worship, moral beliefs and values, and emphasis on family life (although also some distinct differences). Because of the similarity in belief and practice, it is not surprising that research on mental health and devout religious involvement in both these religious traditions has tended to produce similar results. Religious psychotherapies within these faith traditions have been developed and are now being refined and used in clinical trials to determine if integrating patients' religious resources into therapy is more or less effective than conventional therapies in relieving the symptoms of depression and anxiety.

  18. Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014.

    PubMed

    Alraddadi, Basem M; Watson, John T; Almarashi, Abdulatif; Abedi, Glen R; Turkistani, Amal; Sadran, Musallam; Housa, Abeer; Almazroa, Mohammad A; Alraihan, Naif; Banjar, Ayman; Albalawi, Eman; Alhindi, Hanan; Choudhry, Abdul Jamil; Meiman, Jonathan G; Paczkowski, Magdalena; Curns, Aaron; Mounts, Anthony; Feikin, Daniel R; Marano, Nina; Swerdlow, David L; Gerber, Susan I; Hajjeh, Rana; Madani, Tariq A

    2016-01-01

    Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March-November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a case-control design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2-4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV. PMID:26692185

  19. Science and Technology to Advance Regional Security in the Middle East and Central Asia

    SciTech Connect

    Tompson, A F B; Richardson, J H; Ragaini, R C; Knapp, R B; Rosenberg, N D; Smith, D K; Ball, D Y

    2002-10-09

    This paper is concerned with the promotion and advancement of regional security in the Middle East and Central Asia through the development of bilateral and multilateral cooperation on targeted scientific and technical projects. It is widely recognized that increasing tensions and instability in many parts of the world emphasize--or reemphasize--a need to seek and promote regional security in these areas. At the Lawrence Livermore National Laboratory (LLNL), a national security research facility operated for the US Department of Energy, we are pursuing an effort to use science and technology as a ''low risk'' means of engagement in regions of strategic importance to the United States. In particular, we are developing collaborations and cooperative projects among (and between) national laboratory scientists in the US and our various counterparts in the countries of interest.

  20. Infection, Replication, and Transmission of Middle East Respiratory Syndrome Coronavirus in Alpacas

    PubMed Central

    Adney, Danielle R.; Bielefeldt-Ohmann, Helle; Hartwig, Airn E.

    2016-01-01

    Middle East respiratory syndrome coronavirus is a recently emerged pathogen associated with severe human disease. Zoonotic spillover from camels appears to play a major role in transmission. Because of logistic difficulties in working with dromedaries in containment, a more manageable animal model would be desirable. We report shedding and transmission of this virus in experimentally infected alpacas (n = 3) or those infected by contact (n = 3). Infectious virus was detected in all infected animals and in 2 of 3 in-contact animals. All alpacas seroconverted and were rechallenged 70 days after the original infection. Experimentally infected animals were protected against reinfection, and those infected by contact were partially protected. Necropsy specimens from immunologically naive animals (n = 3) obtained on day 5 postinfection showed virus in the upper respiratory tract. These data demonstrate efficient virus replication and animal-to-animal transmission and indicate that alpacas might be useful surrogates for camels in laboratory studies. PMID:27070385

  1. The next generation of public health approaches to asthma in Asia and the Middle East.

    PubMed

    Van Sickle, David

    2010-07-01

    Chronic respiratory diseases now affect more than half a billion people worldwide and their importance as a global health problem has risen dramatically in recent years, prompting intense epidemiological investigation and the launch of numerous initiatives. Across Asia and the Middle East, a variety of environmental exposures increase the risk for the onset or exacerbation of chronic respiratory disease, resulting in a considerable burden of morbidity and mortality. This article outlines new possibilities for public health surveillance of environmental exposures and chronic respiratory disease built around an emerging model of participatory public health: a decentralized approach that involves citizens in the collection and analysis of data, harnesses pervasive technology such as mobile phones and distributed sensors, and provides an open platform for public-private collaboration.

  2. Comment on the implications of external price referencing of pharmaceuticals in Middle East countries.

    PubMed

    Carapinha, João L

    2016-01-01

    External Price Referencing (EPR) is frequently used by countries to control pharmaceutical prices but studies to substantiate its use in the Middle East (ME) is lacking. The paper by Kalo et al set-out to fill this lacuna through three objectives: i) to document the use of EPR in 7 ME countries, ii) to assess whether pharmaceutical EPR resulted in a narrow price corridor for patented pharmaceuticals, and iii) to analyse factors influencing pharmaceutical prices. This comment discusses why the paper fell short of achieving these objectives and over-stated the results. Despite a thought-provoking contribution, objective 1 presented few new insights on EPR mechanisms, objective 2 deployed an inappropriate research design, and the policy implications of objective 3 are voided given the choice of explanatory variables.

  3. Outbreak of Middle East Respiratory Syndrome at Tertiary Care Hospital, Jeddah, Saudi Arabia, 2014

    PubMed Central

    Hastings, Deborah L.; Tokars, Jerome I.; Abdel Aziz, Inas Zakaria A.M.; Alkhaldi, Khulud Z.; Bensadek, Areej T.; Alraddadi, Basem M.; Jokhdar, Hani; Jernigan, John A.; Garout, Mohammed A.; Tomczyk, Sara M.; Oboho, Ikwo K.; Geller, Andrew I.; Arinaminpathy, Nimalan; Swerdlow, David L.

    2016-01-01

    During March–May 2014, a Middle East respiratory syndrome (MERS) outbreak occurred in Jeddah, Saudi Arabia, that included many persons who worked or received medical treatment at King Fahd General Hospital. We investigated 78 persons who had laboratory-confirmed MERS during March 2–May 10 and documented contact at this hospital. The 78 persons with MERS comprised 53 patients, 16 healthcare workers, and 9 visitors. Among the 53 patients, the most probable sites of acquisition were the emergency department (22 patients), inpatient areas (17), dialysis unit (11), and outpatient areas (3). Infection control deficiencies included limited separation of suspected MERS patients, patient crowding, and inconsistent use of infection control precautions; aggressive improvements in these deficiencies preceded a decline in cases. MERS coronavirus transmission probably was multifocal, occurring in multiple hospital settings. Continued vigilance and strict application of infection control precautions are necessary to prevent future MERS outbreaks. PMID:27089550

  4. Silent Epidemic of Depression in Women in the Middle East and North Africa Region

    PubMed Central

    Eloul, Liyam; Ambusaidi, Aamal; Al-Adawi, Samir

    2009-01-01

    Background: As the world is being gripped by economic depression, international psychological epidemiologists have amassed evidence to suggest that psychological depression and its variants are becoming leading contributors to the global burden of disease with the Middle East and North Africa (MENA) region being no exception. Aim: The main aim of the present discourse, based on a review of the available literature, is to discuss critically whether women in the MENA region have a higher rate of psychological depression than those in other parts of the globe. Result: From the present synthesis, it emerges that the rate of depression may not be necessarily unique to the region. Conclusion: Although no society has totally overcome the marginalisation and lack of empowerment of women, in order to come to grips to this complex issue more vigorously designed epidemiological studies, using taxonomies that are standardised for cross-cultural populations, are needed to quantify the psychological functioning of women. PMID:21509269

  5. Diet, Genetics, and Disease: A Focus on the Middle East and North Africa Region

    PubMed Central

    Fahed, Akl C.; El-Hage-Sleiman, Abdul-Karim M.; Farhat, Theresa I.; Nemer, Georges M.

    2012-01-01

    The Middle East and North Africa (MENA) region suffers a drastic change from a traditional diet to an industrialized diet. This has led to an unparalleled increase in the prevalence of chronic diseases. This review discusses the role of nutritional genomics, or the dietary signature, in these dietary and disease changes in the MENA. The diet-genetics-disease relation is discussed in detail. Selected disease categories in the MENA are discussed starting with a review of their epidemiology in the different MENA countries, followed by an examination of the known genetic factors that have been reported in the disease discussed, whether inside or outside the MENA. Several diet-genetics-disease relationships in the MENA may be contributing to the increased prevalence of civilization disorders of metabolism and micronutrient deficiencies. Future research in the field of nutritional genomics in the MENA is needed to better define these relationships. PMID:22536488

  6. Mycotoxin occurrence in commodities, feeds and feed ingredients sourced in the Middle East and Africa

    PubMed Central

    Rodrigues, I.; Handl, J.; Binder, E.M.

    2011-01-01

    Between February and October 2009, 324 grain, feed and feed commodity samples were sourced directly at animal farms or feed production sites in Middle East and Africa and tested for the presence of A- and B-trichothecenes, zearalenone, fumonisins, aflatoxins and ochratoxin A, or for selected groups of mycotoxins only. Samples were analyzed after clean-up by immunoaffinity or solid-phase extraction followed by HPLC with derivatization where appropriate and fluorescence, UV or mass spectrometric detection. The percentage of positive samples of B-trichothecenes ranged from 0 to 87% of tested samples. The prevalence of fumonisins in the different countries was >50% in most cases. Zearalenone was present in tested commodities from all countries except three. The presence of aflatoxin in analyzed samples varied from 0 to 94%. Ochratoxin A was present in 67% of samples in Sudan and in 100% of Nigerian samples. No A-trichothecenes were found in this survey. PMID:24786003

  7. Transmission of Middle East Respiratory Syndrome Coronavirus Infections in Healthcare Settings, Abu Dhabi

    PubMed Central

    Nguyen, Duc; Aden, Bashir; Al Bandar, Zyad; Al Dhaheri, Wafa; Abu Elkheir, Kheir; Khudair, Ahmed; Al Mulla, Mariam; El Saleh, Feda; Imambaccus, Hala; Al Kaabi, Nawal; Sheikh, Farrukh Amin; Sasse, Jurgen; Turner, Andrew; Abdel Wareth, Laila; Weber, Stefan; Al Ameri, Asma; Abu Amer, Wesal; Alami, Negar N.; Bunga, Sudhir; Haynes, Lia M.; Hall, Aron J.; Kallen, Alexander J.; Kuhar, David; Pham, Huong; Pringle, Kimberly; Tong, Suxiang; Whitaker, Brett L.; Gerber, Susan I.; Al Hosani, Farida Ismail

    2016-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) infections sharply increased in the Arabian Peninsula during spring 2014. In Abu Dhabi, United Arab Emirates, these infections occurred primarily among healthcare workers and patients. To identify and describe epidemiologic and clinical characteristics of persons with healthcare-associated infection, we reviewed laboratory-confirmed MERS-CoV cases reported to the Health Authority of Abu Dhabi during January 1, 2013–May 9, 2014. Of 65 case-patients identified with MERS-CoV infection, 27 (42%) had healthcare-associated cases. Epidemiologic and genetic sequencing findings suggest that 3 healthcare clusters of MERS-CoV infection occurred, including 1 that resulted in 20 infected persons in 1 hospital. MERS-CoV in healthcare settings spread predominantly before MERS-CoV infection was diagnosed, underscoring the importance of increasing awareness and infection control measures at first points of entry to healthcare facilities. PMID:26981708

  8. Comparative SWOT analysis of strategic environmental assessment systems in the Middle East and North Africa region.

    PubMed

    Rachid, G; El Fadel, M

    2013-08-15

    This paper presents a SWOT analysis of SEA systems in the Middle East North Africa region through a comparative examination of the status, application and structure of existing systems based on country-specific legal, institutional and procedural frameworks. The analysis is coupled with the multi-attribute decision making method (MADM) within an analytical framework that involves both performance analysis based on predefined evaluation criteria and countries' self-assessment of their SEA system through open-ended surveys. The results show heterogenous status with a general delayed progress characterized by varied levels of weaknesses embedded in the legal and administrative frameworks and poor integration with the decision making process. Capitalizing on available opportunities, the paper highlights measures to enhance the development and enactment of SEA in the region.

  9. A call-to-action from the feedM.E. Middle East study group

    PubMed Central

    Al-Zeer, Osama; Ozcagli, Tahsin G.; Uyar, Mehmet

    2015-01-01

    Up to 50% of hospitalized patients worldwide are malnourished or at risk of malnutrition. Guidelines recommend nutritional screening of all patients on hospital admission. Results from studies of hospitalized patients show that screening, with follow-up nutritional assessment and care when indicated, can improve patients’ clinical outcomes and reduce healthcare costs. Despite compelling evidence, attention to nutritional care remains suboptimal in clinical settings worldwide. The feedM.E. Global Study Group developed a simple, stepwise Nutrition Care Pathway to facilitate best-practice nutrition care. This pathway guides clinicians to screen patients’ nutritional status on hospital admission or at initiation of care; intervene promptly with nutrition care when needed; and supervene or follow-up routinely with adjustment and reinforcement of nutrition care plans. The feedM.E. Middle East Study Group seeks to extend this program to our region. We advise clinicians to adopt and adapt the Nutrition Care Pathway, bringing quality nutrition care to everyday practice. PMID:26219439

  10. Middle East Respiratory Syndrome Infection Control and Prevention Guideline for Healthcare Facilities.

    PubMed

    Kim, Jin Yong; Song, Joon Young; Yoon, Young Kyung; Choi, Seong-Ho; Song, Young Goo; Kim, Sung-Ran; Son, Hee-Jung; Jeong, Sun-Young; Choi, Jung-Hwa; Kim, Kyung Mi; Yoon, Hee Jung; Choi, Jun Yong; Kim, Tae Hyong; Choi, Young Hwa; Kim, Hong Bin; Yoon, Ji Hyun; Lee, Jacob; Eom, Joong Sik; Lee, Sang-Oh; Oh, Won Sup; Choi, Jung-Hyun; Yoo, Jin-Hong; Kim, Woo Joo; Cheong, Hee Jin

    2015-12-01

    Middle East Respiratory Syndrome (MERS) is an acute viral respiratory illness with high mortality caused by a new strain of betacoronavirus (MERS-CoV). Since the report of the first patient in Saudi Arabia in 2012, large-scale outbreaks through hospital-acquired infection and inter-hospital transmission have been reported. Most of the patients reported in South Korea were also infected in hospital settings. Therefore, to eliminate the spread of MERS-CoV, infection prevention and control measures should be implemented with rigor. The present guideline has been drafted on the basis of the experiences of infection control in the South Korean hospitals involved in the recent MERS outbreak and on domestic and international infection prevention and control guidelines. To ensure efficient MERS-CoV infection prevention and control, care should be taken to provide comprehensive infection control measures including contact control, hand hygiene, personal protective equipment, disinfection, and environmental cleaning.

  11. Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea, 2015

    PubMed Central

    2015-01-01

    Objectives The outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the Republic of Korea started from the index case who developed fever after returning from the Middle East. He infected 26 cases in Hospital C, and consecutive nosocomial transmission proceeded throughout the nation. We provide an epidemiologic description of the outbreak, as of July 2015. Methods Epidemiological research was performed by direct interview of the confirmed patients and reviewing medical records. We also analyzed the incubation period, serial interval, the characteristics of superspreaders, and factors associated with mortality. Full genome sequence was obtained from sputum specimens of the index patient. Results A total of 186 confirmed patients with MERS-CoV infection across 16 hospitals were identified in the Republic of Korea. Some 44.1% of the cases were patients exposed in hospitals, 32.8% were caregivers, and 13.4% were healthcare personnel. The most common presenting symptom was fever and chills. The estimated incubation period was 6.83 days and the serial interval was 12.5 days. A total of 83.2% of the transmission events were epidemiologically linked to five superspreaders, all of whom had pneumonia at presentation and contacted hundreds of people. Older age [odds ratio (OR) = 4.86, 95% confidence interval (CI) 1.90–12.45] and underlying respiratory disease (OR = 4.90, 95% CI 1.64–14.65) were significantly associated with mortality. Phylogenetic analysis showed that the MERS-CoV of the index case clustered closest with a recent virus from Riyadh, Saudi Arabia. Conclusion A single imported MERS-CoV infection case imposed a huge threat to public health and safety. This highlights the importance of robust preparedness and optimal infection prevention control. The lessons learned from the current outbreak will contribute to more up-to-date guidelines and global health security. PMID:26473095

  12. Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

    PubMed Central

    Chan, Jasper F. W.; Lau, Susanna K. P.; To, Kelvin K. W.; Cheng, Vincent C. C.; Woo, Patrick C. Y.

    2015-01-01

    SUMMARY The source of the severe acute respiratory syndrome (SARS) epidemic was traced to wildlife market civets and ultimately to bats. Subsequent hunting for novel coronaviruses (CoVs) led to the discovery of two additional human and over 40 animal CoVs, including the prototype lineage C betacoronaviruses, Tylonycteris bat CoV HKU4 and Pipistrellus bat CoV HKU5; these are phylogenetically closely related to the Middle East respiratory syndrome (MERS) CoV, which has affected more than 1,000 patients with over 35% fatality since its emergence in 2012. All primary cases of MERS are epidemiologically linked to the Middle East. Some of these patients had contacted camels which shed virus and/or had positive serology. Most secondary cases are related to health care-associated clusters. The disease is especially severe in elderly men with comorbidities. Clinical severity may be related to MERS-CoV's ability to infect a broad range of cells with DPP4 expression, evade the host innate immune response, and induce cytokine dysregulation. Reverse transcription-PCR on respiratory and/or extrapulmonary specimens rapidly establishes diagnosis. Supportive treatment with extracorporeal membrane oxygenation and dialysis is often required in patients with organ failure. Antivirals with potent in vitro activities include neutralizing monoclonal antibodies, antiviral peptides, interferons, mycophenolic acid, and lopinavir. They should be evaluated in suitable animal models before clinical trials. Developing an effective camel MERS-CoV vaccine and implementing appropriate infection control measures may control the continuing epidemic. PMID:25810418

  13. Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of Korea

    PubMed Central

    Choi, Won Suk; Kang, Cheol-In; Kim, Yonjae; Joh, Joon Sung; Shin, Hyoung-Shik; Kim, Gayeon; Peck, Kyong Ran; Chung, Doo Ryeon; Kim, Hye Ok; Song, Sook Hee; Kim, Yang Ree; Sohn, Kyung Mok; Jung, Younghee; Bang, Ji Hwan; Kim, Nam Joong; Lee, Kkot Sil; Jeong, Hye Won; Rhee, Ji-Young; Kim, Eu Suk; Woo, Heungjeong; Oh, Won Sup; Huh, Kyungmin; Lee, Young Hyun; Song, Joon Young; Lee, Jacob; Lee, Chang-Seop; Kim, Baek-Nam; Choi, Young Hwa; Jeong, Su Jin; Lee, Jin-Soo; Yoon, Ji Hyun; Wi, Yu Mi; Joung, Mi Kyong; Park, Seong Yeon; Lee, Sun Hee; Jung, Sook-In; Kim, Shin-Woo; Lee, Jae Hoon; Lee, Hyuck; Ki, Hyun Kyun

    2016-01-01

    Background From May to July 2015, the Republic of Korea experienced the largest outbreak of Middle East respiratory syndrome (MERS) outside the Arabian Peninsula. A total of 186 patients, including 36 deaths, had been diagnosed with MERS-coronavirus (MERS-CoV) infection as of September 30th, 2015. Materials and Methods We obtained information of patients who were confirmed to have MERS-CoV infection. MERS-CoV infection was diagnosed using real-time reverse-transcriptase polymerase chain reaction assay. Results The median age of the patients was 55 years (range, 16 to 86). A total of 55.4% of the patients had one or more coexisting medical conditions. The most common symptom was fever (95.2%). At admission, leukopenia (42.6%), thrombocytopenia (46.6%), and elevation of aspartate aminotransferase (42.7%) were observed. Pneumonia was detected in 68.3% of patients at admission and developed in 80.8% during the disease course. Antiviral agents were used for 74.7% of patients. Mechanical ventilation, extracorporeal membrane oxygenation, and convalescent serum were employed for 24.5%, 7.1%, and 3.8% of patients, respectively. Older age, presence of coexisting medical conditions including diabetes or chronic lung disease, presence of dyspnea, hypotension, and leukocytosis at admission, and the use of mechanical ventilation were revealed to be independent predictors of death. Conclusion The clinical features of MERS-CoV infection in the Republic of Korea were similar to those of previous outbreaks in the Middle East. However, the overall mortality rate (20.4%) was lower than that in previous reports. Enhanced surveillance and active management of patients during the outbreak may have resulted in improved outcomes. PMID:27433382

  14. The Potential Uses of Commercial Satellite Imagery in the Middle East

    SciTech Connect

    Vannoni, M.G.

    1999-06-08

    It became clear during the workshop that the applicability of commercial satellite imagery to the verification of future regional arms control agreements is limited at this time. Non-traditional security topics such as environmental protection, natural resource management, and the development of infrastructure offer the more promising applications for commercial satellite imagery in the short-term. Many problems and opportunities in these topics are regional, or at least multilateral, in nature. A further advantage is that, unlike arms control and nonproliferation applications, cooperative use of imagery in these topics can be done independently of the formal Middle East Peace Process. The value of commercial satellite imagery to regional arms control and nonproliferation, however, will increase during the next three years as new, more capable satellite systems are launched. Aerial imagery, such as that used in the Open Skies Treaty, can also make significant contributions to both traditional and non-traditional security applications but has the disadvantage of requiring access to national airspace and potentially higher cost. There was general consensus that commercial satellite imagery is under-utilized in the Middle East and resources for remote sensing, both human and institutional, are limited. This relative scarcity, however, provides a natural motivation for collaboration in non-traditional security topics. Collaborations between scientists, businesses, universities, and non-governmental organizations can work at the grass-roots level and yield contributions to confidence building as well as scientific and economic results. Joint analysis projects would benefit the region as well as establish precedents for cooperation.

  15. Overview of cervical cancer screening practices in the extended Middle East and North Africa countries.

    PubMed

    Sancho-Garnier, Hélène; Khazraji, Youssef Chami; Cherif, Moktar Hamdi; Mahnane, Abbes; Hsairi, Mohamed; El Shalakamy, Amr; Osgul, Nejat; Tuncer, Murat; Jumaan, Aisha O; Seoud, Muhieddine

    2013-12-30

    National Organized Cervical Cancer Screening (NOCCS) programs are lacking in most of the "Extended Middle East and North Africa" (EMENA) countries. Consequently, most cervical cancers are diagnosed late and are associated with high mortality. In fact, in most of these countries, national mortality data are unknown due to the absence of population-based mortality registries. Most countries of the EMENA practice more or less limited opportunistic, cytology-based, screening tests, which often lack quality assurance and follow-up care. A few countries, within the initiation of a National Cancer Control Plan, have just started to implement organized screening programs using, for cervical cancer detection, visual inspection with acetic acid (Morocco) or cytology (Turkey). Moreover, most countries of the EMENA lack national guideline, as well as resources for the management of abnormal cytologic screening (or any other screening test). The main obstacle for the implementation of NOCCS is a lack of political understanding to support such public health programs and provide the necessary resources. Other obstacles that hinder the participation of women in cervical screening include a lack of knowledge of the disease, socio-religious and cultural barriers, and geographic and economic difficulties in accessing medical services. These countries are already convinced that prevention of cervical cancers in women who have cervical intraepithelial neoplasia is possible through various screening and treatment algorithms, but most countries still need to invest in well organized programs that can reduce cervical cancer incidence and mortality in women. This article forms part of a regional report entitled "Comprehensive Control of HPV Infections and Related Diseases in the Extended Middle East and North Africa Region" Vaccine Volume 31, Supplement 6, 2013. Updates of the progress in the field are presented in a separate monograph entitled "Comprehensive Control of HPV Infections and

  16. MENA 1.1 - An Updated Geophysical Regionalization of the Middle East and North Africa

    SciTech Connect

    Walters, B.; Pasyanos, M.E.; Bhattacharyya, J.; O'Boyle, J.

    2000-03-01

    This short report provides an update to the earlier LLNL paper entitled ''Preliminary Definition of Geophysical Regions for the Middle East and North Africa'' (Sweeney and Walter, 1998). This report is designed to be used in combination with that earlier paper. The reader is referred to Sweeney and Walter (1998) for all details, including definitions, references, uses, shortcomings, etc., of the regionalization process. In this report we will discuss only those regions in which we have changed the boundaries or velocity structure from that given by the original paper. The paper by Sweeney and Walter (1998) drew on a variety of sources to estimate a preliminary, first-order regionalization of the Middle East and North Africa (MENA), providing regional boundaries and velocity models within each region. The model attempts to properly account for major structural discontinuities and significant crustal thickness and velocity variations on a gross scale. The model can be used to extrapolate sparse calibration data within a distinct geophysical region. This model can also serve as a background model in the process of forming station calibration maps using intelligent interpolation techniques such as kriging, extending the calibration into aseismic areas. Such station maps can greatly improve the ability to locate and identify seismic events, which in turn improves the ability to seismically monitor for underground nuclear testing. The original model from Sweeney and Walter (1998) was digitized to a 1{sup o} resolution, for simplicity we will hereafter refer to this model as MENA 1.0. The new model described here has also been digitized to a 1{sup o} resolution and will be referred to as MENA1.1 throughout this report.

  17. Geological and geometrical characteristics of reservoir fracturing throughout the Middle East

    SciTech Connect

    Nurmi, R. ) Akbar, M. ); Standen, E. )

    1993-09-01

    The geometry and basic characteristics (length, density/intensity, aperture, and porosity) of fractures (joints) have been defined recently for a number of Middle East reservoirs. The factors that determine the occurrence of natural, open, permeable fractures within Middle East reservoirs are nature and degree of folding and/or faulting, in-situ stresses, and changes in rock properties such as porosity, lithology, and especially shaliness. Fracture distribution and orientation within Mesozoic Arabian/Persian Gulf halo-kinetic structures is important to reservoir development and modeling, although the fractures generally only assist productivity. In the deeper Paleozoic reservoirs, fractures become increasingly important. Fractures are best developed in relatively anhydrite free, low porosity, dolomite facies, and with few exceptions their orientation is related to regional trends, only slightly modified by local tectonic features. Exploration for deep-fracture reservoirs needs to consider that the probability of uncemented fractures will be present only where the timing of hydrocarbon migration was close in timing to fracturing. Examination of fractured reservoirs in the Zagros-Bitlis orogenic belt from Turkey through Syria, Iraq, Iran and the northern Emirates demonstrates that the fracturing is dominantly related to folding, with only minor karst fracturing or fault-related fracturing, whereas the fractures in the Gulf of Suez are closely related to the faulting history with some of the most intense fracturing of the low-porosity Eocene limestones forming a fracture reservoir near fault zones. Studies of basement fracturing reveals that decreases in fracture apertures generally accompanies increases in fracture density. The distribution of fractures within the northern Sinai closely fit a wrench-tectonic model, where the greatest density and largest apertures occur in the dolomitic facies and have an orientation parallel to synthetic faulting of the wrench system.

  18. Overview of cervical cancer screening practices in the extended Middle East and North Africa countries.

    PubMed

    Sancho-Garnier, Hélène; Khazraji, Youssef Chami; Cherif, Moktar Hamdi; Mahnane, Abbes; Hsairi, Mohamed; El Shalakamy, Amr; Osgul, Nejat; Tuncer, Murat; Jumaan, Aisha O; Seoud, Muhieddine

    2013-12-30

    National Organized Cervical Cancer Screening (NOCCS) programs are lacking in most of the "Extended Middle East and North Africa" (EMENA) countries. Consequently, most cervical cancers are diagnosed late and are associated with high mortality. In fact, in most of these countries, national mortality data are unknown due to the absence of population-based mortality registries. Most countries of the EMENA practice more or less limited opportunistic, cytology-based, screening tests, which often lack quality assurance and follow-up care. A few countries, within the initiation of a National Cancer Control Plan, have just started to implement organized screening programs using, for cervical cancer detection, visual inspection with acetic acid (Morocco) or cytology (Turkey). Moreover, most countries of the EMENA lack national guideline, as well as resources for the management of abnormal cytologic screening (or any other screening test). The main obstacle for the implementation of NOCCS is a lack of political understanding to support such public health programs and provide the necessary resources. Other obstacles that hinder the participation of women in cervical screening include a lack of knowledge of the disease, socio-religious and cultural barriers, and geographic and economic difficulties in accessing medical services. These countries are already convinced that prevention of cervical cancers in women who have cervical intraepithelial neoplasia is possible through various screening and treatment algorithms, but most countries still need to invest in well organized programs that can reduce cervical cancer incidence and mortality in women. This article forms part of a regional report entitled "Comprehensive Control of HPV Infections and Related Diseases in the Extended Middle East and North Africa Region" Vaccine Volume 31, Supplement 6, 2013. Updates of the progress in the field are presented in a separate monograph entitled "Comprehensive Control of HPV Infections and

  19. The Spread of Tomato Yellow Leaf Curl Virus from the Middle East to the World

    PubMed Central

    Lefeuvre, Pierre; Martin, Darren P.; Harkins, Gordon; Lemey, Philippe; Gray, Alistair J. A.; Meredith, Sandra; Lakay, Francisco; Monjane, Adérito; Lett, Jean-Michel; Varsani, Arvind; Heydarnejad, Jahangir

    2010-01-01

    The ongoing global spread of Tomato yellow leaf curl virus (TYLCV; Genus Begomovirus, Family Geminiviridae) represents a serious looming threat to tomato production in all temperate parts of the world. Whereas determining where and when TYLCV movements have occurred could help curtail its spread and prevent future movements of related viruses, determining the consequences of past TYLCV movements could reveal the ecological and economic risks associated with similar viral invasions. Towards this end we applied Bayesian phylogeographic inference and recombination analyses to available TYLCV sequences (including those of 15 new Iranian full TYLCV genomes) and reconstructed a plausible history of TYLCV's diversification and movements throughout the world. In agreement with historical accounts, our results suggest that the first TYLCVs most probably arose somewhere in the Middle East between the 1930s and 1950s (with 95% highest probability density intervals 1905–1972) and that the global spread of TYLCV only began in the 1980s after the evolution of the TYLCV-Mld and -IL strains. Despite the global distribution of TYLCV we found no convincing evidence anywhere other than the Middle East and the Western Mediterranean of epidemiologically relevant TYLCV variants arising through recombination. Although the region around Iran is both the center of present day TYLCV diversity and the site of the most intensive ongoing TYLCV evolution, the evidence indicates that the region is epidemiologically isolated, which suggests that novel TYLCV variants found there are probably not direct global threats. We instead identify the Mediterranean basin as the main launch-pad of global TYLCV movements. PMID:21060815

  20. Guidelines for acute management of hyperammonemia in the Middle East region

    PubMed Central

    Alfadhel, Majid; Mutairi, Fuad Al; Makhseed, Nawal; Jasmi, Fatma Al; Al-Thihli, Khalid; Al-Jishi, Emtithal; AlSayed, Moeenaldeen; Al-Hassnan, Zuhair N; Al-Murshedi, Fathiya; Häberle, Johannes; Ben-Omran, Tawfeg

    2016-01-01

    Background Hyperammonemia is a life-threatening event that can occur at any age. If treated, the early symptoms in all age groups could be reversible. If untreated, hyperammonemia could be toxic and cause irreversible brain damage to the developing brain. Objective There are major challenges that worsen the outcome of hyperammonemic individuals in the Middle East. These include: lack of awareness among emergency department physicians about proper management of hyperammonemia, strained communication between physicians at primary, secondary, and tertiary hospitals, and shortage of the medications used in the acute management of hyperammonemia. Therefore, the urge to develop regional guidelines is extremely obvious. Method We searched PubMed and Embase databases to include published materials from 2011 to 2014 that were not covered by the European guidelines, which was published in 2012. We followed the process of a Delphi conference and involved one preliminary meeting and two follow-up meetings with email exchanges between the Middle East Hyperammonemia and Urea Cycle Disorders Scientific Group regarding each draft of the manuscript. Results and discussion We have developed consensus guidelines based on the highest available level of evidence. The aim of these guidelines is to homogenize and harmonize the treatment protocols used for patients with acute hyperammonemia, and to provide a resource to not only metabolic physicians, but also physicians who may come in contact with individuals with acute hyperammonemia. Conclusion These suggested guidelines aim to ease the challenges faced by physicians dealing with acute hyperammonemia in the region. In addition, guidelines have demonstrated useful collaboration between experts in the region, and provides information that will hopefully improve the outcomes of patients with acute hyperammonemia. PMID:27099506

  1. Prevalence and Severity of Oral Diseases in the Africa and Middle East Region.

    PubMed

    Abid, A; Maatouk, F; Berrezouga, L; Azodo, C; Uti, O; El-Shamy, H; Oginni, A

    2015-07-01

    This review aims to determine the prevalence and severity of oral health diseases in the Africa and Middle East region (AMER). The profile of oral diseases is not homogeneous across the AMER. There are large disparities between groups. Reliable data are scarce. The prevalence and severity of oral diseases appear to be increasing in the African region, as does associated morbidity. There are substantial differences in inequalities in oral health. Dental caries prevalence is less severe in most African countries than in developed countries, but the high rate of untreated caries reflects the limited resources available and difficulties of access and affordability to essential oral health care services. The prevalence of gingival inflammation is very high in all age groups in several African countries. The prevalence of maxillofacial trauma has increased in many countries, with a wide variation of the incidence and high prevalence of traumatic dental injuries in primary and permanent teeth. Orofacial clefts are among the most common birth defects. Annual incidence of oral cancer is estimated as 25 cases per 100,000 people in Africa. Noma is a major public health problem for the Middle East and North African (MENA) region. Data about human immunodeficiency virus/AIDS are limited, particularly in the MENA region. According to the World Health Organization Regional Committee for Africa report, some fundamental key basic knowledge gaps need to be underlined. They include inequalities in oral health, low priority for oral health, lack of adequate funding, inadequate dental student training, obstacles to medical and dental research, and poor databases. There are very few effective public prevention and oral health promotion programs in the AMER. Universal health coverage is not achievable without scientific research on the effectiveness of health promotion interventions.

  2. A novel dromedary camel enterovirus in the family Picornaviridae from dromedaries in the Middle East.

    PubMed

    Woo, Patrick C Y; Lau, Susanna K P; Li, Tong; Jose, Shanty; Yip, Cyril C Y; Huang, Yi; Wong, Emily Y M; Fan, Rachel Y Y; Cai, Jian-Piao; Wernery, Ulrich; Yuen, Kwok-Yung

    2015-07-01

    The recent emergence of Middle East respiratory syndrome coronavirus from the Middle East and the discovery of the virus from dromedary camels have boosted interest in the search for novel viruses in dromedaries. Whilst picornaviruses are known to infect various animals, their existence in dromedaries was unknown. We describe the discovery of a novel picornavirus, dromedary camel enterovirus (DcEV), from dromedaries in Dubai. Among 215 dromedaries, DcEV was detected in faecal samples of four (1.9 %) dromedaries [one (0.5 %) adult dromedary and three (25 %) dromedary calves] by reverse transcription PCR. Analysis of two DcEV genomes showed that DcEV was clustered with other species of the genus Enterovirus and was most closely related to and possessed highest amino acid identities to the species Enterovirus E and Enterovirus F found in cattle. The G+C content of DcEV was 45 mol%, which differed from that of Enterovirus E and Enterovirus F (49-50 mol%) by 4-5 %. Similar to other members of the genus Enterovirus, the 5' UTR of DcEV possessed a putative type I internal ribosome entry site. The low ratios of the number of nonsynonymous substitutions per non-synonymous site to the number of synonymous substitutions per synonymous site (Ka/Ks) of various coding regions suggested that dromedaries are the natural reservoir in which DcEV has been stably evolving. These results suggest that DcEV is a novel species of the genus Enterovirus in the family Picornaviridae. Western blot analysis using recombinant DcEV VP1 polypeptide showed a high seroprevalence of 52 % among serum samples from 172 dromedaries for IgG, concurring with its much higher infection rates in dromedary calves than in adults. Further studies are important to understand the pathogenicity, epidemiology and genetic evolution of DcEV in this unique group of animals.

  3. Ancient glaciations and hydrocarbon accumulations in North Africa and the Middle East

    NASA Astrophysics Data System (ADS)

    Le Heron, Daniel Paul; Craig, Jonathan; Etienne, James L.

    2009-04-01

    At least six glaciations are purported to have affected North Africa and the Middle East region over the last one billion years, including two in the Cryogenian (Neoproterozoic), Hirnantian (Late Ordovician), Silurian, Carboniferous and Early Permian events. The sedimentary record associated with these glaciations, together with the intensity to which each has been investigated, is highly variable. As hydrocarbon exploration proceeds aggressively across the North Africa and Middle East regions, we review the relationship between glaciation and hydrocarbon accumulations. With the exception of Oman, and locally Egypt, which were tectonically active both during the Neoproterozoic and Early Palaeozoic all glaciations took place along an essentially stable passive continental margin. During the Neoproterozoic, two glaciations are recognised, referred to as older and younger Cryogenian glaciations respectively. Both of these Cryogenian events are preserved in Oman; only the younger Cryogenian has been reported in North Africa in Mauritania and Mali at the flanks of the Taoudenni Basin. The process of initial deglaciation in younger Cryogenian glaciations resulted in incision, at least locally producing large-bedrock palaeovalleys in Oman, and the deposition of glacial diamictites, gravels, sandstones and mudstones. As deglaciation progressed "cap carbonates" were deposited, passing vertically into shale with evidence for deposition in an anoxic environment. Hence, younger Cryogenian deglaciation may be associated with hydrocarbon source rock deposits. Hirnantian (Late Ordovician) glaciation was short lived (< 0.5 Myr) and affected intracratonic basins of Mauritania, Morocco, Algeria, Libya, Egypt and Saudi Arabia. The organisation of the glacial sedimentary record is considered to be controlled at the basin-scale by the location of fast-flowing ice streams active during glacial maxima, and by the processes of meltwater release during glacial recession. In these latter

  4. Strategic planning by the palliative care steering committee of the Middle East Cancer Consortium.

    PubMed

    Moore, Shannon Y; Pirrello, Rosene D; Christianson, Sonya K; Ferris, Frank D

    2011-04-01

    High quality comprehensive palliative care is a critical need for millions of patients and families, but remains only a dream in many parts of the world. The failure to do a strategic planning process is one obstacle to advancing education and pain prevention and relief. The Middle Eastern Cancer Consortium Steering Committee attendees completed an initial strategic planning process and identified "developmental steps" to advance palliative care. Underscoring the multi-disciplinary nature of comprehensive palliative care, discipline-specific planning was done (adult and pediatric cancer and medicine, pharmacy, nursing) in a separate process from country-specific planning. Delineating the layers of intersection and differences between disciplines and countries was very powerful. Finding the common strengths and weaknesses in the status quo creates the potential for a more powerful regional response to the palliative care needs. Implementing and refining these preliminary strategic plans will augment and align the efforts to advance palliative care education and pain management in the Middle East. The dream to prevent and relieve suffering for millions of patients with advanced disease will become reality with a powerful strategic planning process well implemented.

  5. Experiences in control of avian influenza in Europe, the Russian Federation and the Middle East.

    PubMed

    Brown, I H; Pittman, M; Irza, V; Laddomada, A

    2007-01-01

    An unprecedented global epidemic of highly pathogenic avian influenza virus H5N1 has and continues to present enormous challenges to the international community for control in the animal reservoir. Enhanced biosecurity, good surveillance, both passive and active, supplemented by strong veterinary services, can reduce the risk for incursion and subsequent spread in free countries. Surveillance of mortality and laboratory testing among wild birds are useful early indicators of incursion of the virus into areas in which domestic poultry are not infected. Conventional control methods used widely in Europe and the Middle Eastern region involve stamping-out, zoning, quarantine, movement restrictions, enhanced surveillance and disinfection. Use of preventive vaccination is increasing in the region. In the Russian Federation, all backyard poultry considered to be at high risk for infection have been vaccinated since 2006. Several countries in the Middle East permit the use of vaccine, although rarely as part of a formal statutory programme. In the European Union, conventional approaches for control have proved effective, but both emergency and preventive vaccination could be used. Application of such programmes would have to be preceded by an evaluation of the risks for introduction and spread and might be restricted.

  6. Conducting Environmental Health Research in the Arabian Middle East: Lessons Learned and Opportunities

    PubMed Central

    El-Sadig, Mohamed; Ali, Habiba I.; Al-Maskari, Fatma; Campbell, Alan; Ng, Shu Wen; Reeves, Lisa; Chan, Ronna L.; Davidson, Christopher A.; Funk, William E.; Boundy, Maryanne G.; Leith, David; Popkin, Barry; Gibson, Jacqueline MacDonald; Rusyn, Ivan; Olshan, Andrew F.

    2012-01-01

    Background: The Arabian Gulf nations are undergoing rapid economic development, leading to major shifts in both the traditional lifestyle and the environment. Although the pace of change is brisk, there is a dearth of environmental health research in this region. Objective: We describe challenges and successes of conducting an environmental epidemiologic study in the United Arab Emirates (UAE), a Gulf nation in the Middle East, with an inter-disciplinary team that includes in-country academic and government collaborators as well as U.S. academic collaborators. Discussion: We present several issues, including study and data collection design, exposure assessment, scheduling and time coordination, quality assurance and quality control, and institutional review board protocols. These topics are considered in a cultural context. Benefits of this research included building linkages among multinational, interdisciplinary team members, generating data for local environmental decision making, and developing local epidemiologic research capacity. The Middle Eastern culture of hospitality greatly benefited the project team. Conclusion: Cultural differences impact multiple aspects of epidemiologic research and should be respectfully addressed. Conducting international population-based environmental research poses many challenges; these challenges can be met successfully with careful planning, cultural knowledge, and flexibility. Lessons learned are applicable to interdisciplinary research all over the world. The research conducted will benefit the environmental and public health agencies of the UAE and provide the nation’s leadership with country-specific environmental health data that can be used to protect the public’s health in a rapidly changing environment. PMID:22356946

  7. An Exploratory Study of Factors That Affect the Research Progress of International PhD Students from the Middle East

    ERIC Educational Resources Information Center

    Khozaei, Fatemeh; Naidu, Sivabala; Khozaei, Zahra; Salleh, Nor Aini

    2015-01-01

    Purpose: Despite the critical issues involving Middle East countries such as war and a drop in currency exchange rates, a large number of students leave their country to pursue a higher education abroad, every year. The purpose of this paper is to understand the difficulties that these students face while conducting their research in a foreign…

  8. A Human Economy: A "Third Way" for the Future of Young People in the Middle East and North Africa

    ERIC Educational Resources Information Center

    Zaalouk, Malak

    2014-01-01

    This paper looks at the vulnerability of today's youth worldwide, with a particular focus on the Middle East and North Africa (MENA), where the proportion of citizens aged 12-24 is particularly high at one-third of the total population. Cursed with poor education and few work opportunities, the youth unemployment rate has risen to 50 per cent…

  9. U.S. Students Study Abroad in the Middle East/North Africa: Factors Influencing Growing Numbers

    ERIC Educational Resources Information Center

    Lane-Toomey, Cara K.; Lane, Shannon R.

    2013-01-01

    The political events of the last decade and the Arab Spring have made it more important than ever for Americans to understand the language, culture, and history of the Middle East/North Africa (MENA) region. Study abroad is one important method that can significantly increase American students' understanding of the Arabic language and the…

  10. Follow-up of Contacts of Middle East Respiratory Syndrome Coronavirus-Infected Returning Travelers, the Netherlands, 2014.

    PubMed

    Mollers, Madelief; Jonges, Marcel; Pas, Suzan D; van der Eijk, Annemiek A; Dirksen, Kees; Jansen, Casper; Gelinck, Luc B S; Leyten, Eliane M S; Thurkow, Ingrid; Groeneveld, Paul H P; van Gageldonk-Lafeber, Arianne B; Koopmans, Marion P; Timen, Aura

    2015-09-01

    Notification of 2 imported cases of infection with Middle East respiratory syndrome coronavirus in the Netherlands triggered comprehensive monitoring of contacts. Observed low rates of virus transmission and the psychological effect of contact monitoring indicate that thoughtful assessment of close contacts is prudent and must be guided by clinical and epidemiologic risk factors.

  11. Moral Reasoning and Student Perceptions of the Middle East: Observations on Student Learning from an Internet Dialog

    ERIC Educational Resources Information Center

    Stover, William J.

    2006-01-01

    This article explores the relationship between the religious based moral reasoning of Judaism and Islam and college student subjects' attitudes toward political entities involved in Middle East conflict, Israel and Arab states. Subjects learn about the moral positions by observing parts of an interactive, Internet dialog among Christian, Jewish,…

  12. Follow-up of Contacts of Middle East Respiratory Syndrome Coronavirus–Infected Returning Travelers, the Netherlands, 2014

    PubMed Central

    Mollers, Madelief; Jonges, Marcel; Pas, Suzan D.; van der Eijk, Annemiek A.; Dirksen, Kees; Jansen, Casper; Gelinck, Luc B.S.; Leyten, Eliane M.S.; Thurkow, Ingrid; Groeneveld, Paul H.P.; van Gageldonk-Lafeber, Arianne B.; Koopmans, Marion P.

    2015-01-01

    Notification of 2 imported cases of infection with Middle East respiratory syndrome coronavirus in the Netherlands triggered comprehensive monitoring of contacts. Observed low rates of virus transmission and the psychological effect of contact monitoring indicate that thoughtful assessment of close contacts is prudent and must be guided by clinical and epidemiologic risk factors. PMID:26291986

  13. A Comprehensive Review of the Status of Early Childhood Development in the Middle East and North Africa.

    ERIC Educational Resources Information Center

    Khattab, Mohammad Salih

    This report reviews the status of early childhood education (ECE) programs in UNICEF's Middle East and North Africa region. The report compiles information about ECE programs in 18 countries based on a questionnaire sent to UNICEF country offices and other sources. The introduction sets out the economic and social rationales for investing in early…

  14. A New Middle East? A Report of FPRI's History Institute for Teachers. Footnotes. Volume 10, Number 1

    ERIC Educational Resources Information Center

    Kuehner, Trudy J.

    2005-01-01

    Understanding the current conflicts and political changes in the Middle East us important for American educators if American students are to understand the dynamics of the region. To discuss these issues, FPRI held its 12th History Institute for Teachers on October 16-17, 2004. Forty teachers from 15 states attended the weekend program at the…

  15. Follow-up of Contacts of Middle East Respiratory Syndrome Coronavirus-Infected Returning Travelers, the Netherlands, 2014.

    PubMed

    Mollers, Madelief; Jonges, Marcel; Pas, Suzan D; van der Eijk, Annemiek A; Dirksen, Kees; Jansen, Casper; Gelinck, Luc B S; Leyten, Eliane M S; Thurkow, Ingrid; Groeneveld, Paul H P; van Gageldonk-Lafeber, Arianne B; Koopmans, Marion P; Timen, Aura

    2015-09-01

    Notification of 2 imported cases of infection with Middle East respiratory syndrome coronavirus in the Netherlands triggered comprehensive monitoring of contacts. Observed low rates of virus transmission and the psychological effect of contact monitoring indicate that thoughtful assessment of close contacts is prudent and must be guided by clinical and epidemiologic risk factors. PMID:26291986

  16. A Multilevel Analysis of the Role of School Quality and Family Background on Students' Mathematics Achievement in the Middle East

    ERIC Educational Resources Information Center

    Kareshki, Hossein; Hajinezhad, Zahra

    2014-01-01

    The purpose of the present study is investigating the correlation between school quality and family socioeconomic background and students' mathematics achievement in the Middle East. The countries in comparison are UAE, Syria, Qatar, Iran, Saudi Arabia, Oman, Lebanon, Jordan, and Bahrain. The study utilized data from IEA's Trends in International…

  17. Two Future American Leaders React to the Middle East Crises of 1939 and 1948: A Documentary Exercise

    ERIC Educational Resources Information Center

    Nurse, Ronald J.

    1974-01-01

    In 1939 and 1948, John Kennedy and Robert Kennedy visited the Middle East, both while seniors in college. This article consists of two letters written to their parents from Palestine assessing the problems of their day between Arab and Jew. Questions to stimulate classroom discussion are included. (Author/RM)

  18. The Quality of Secondary Education in the Middle East and North Africa: What Can We Learn from TIMSS' Results?

    ERIC Educational Resources Information Center

    Bouhlila, Donia Smaali

    2011-01-01

    Research on educational quality has been scarce in the Middle East and North Africa (MENA) region, whereas the debates over educational quality date from 1966 in the USA with the Coleman Report. Fortunately TIMSS (Trends in International Mathematics and Science Study) starts to fill this gap by providing data on students' achievement and for many…

  19. 1. Building 3 east elevation, Building 15 and steel water ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Building 3 east elevation, Building 15 and steel water tank (elevated) to left, stack associated with Building 3 Boiler room, center. View looking west. - John & James Dobson Carpet Mill (West Parcel), Building No. 3, 4041-4055 Ridge Avenue, Philadelphia, Philadelphia County, PA

  20. 1. East apron upper dam with water flowing over overspill. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. East apron upper dam with water flowing over overspill. Photograph taken from crest of lower dam in foreground). VIEW WEST - Loleta Recreation Area, Upper Dam, 6 miles Southeast of interesection of State Route 24041 & State Route 66, Loleta, Elk County, PA

  1. View of water wheel, generator #3 and exciter (at east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of water wheel, generator #3 and exciter (at east end of Childs Powerhouse) on a single shaft. In foreground the governor and shut-off valve are visible. Looking southwest - Childs-Irving Hydroelectric Project, Childs System, Childs Powerhouse, Forest Service Road 708/502, Camp Verde, Yavapai County, AZ

  2. Rayleigh wave group velocity dispersion across Northern Africa, Southern Europe and the Middle East

    SciTech Connect

    McNamara, D.E.; Walter, W.R.

    1997-07-15

    THis report presents preliminary results from a large scale study of surface wave group velocity dispersion throughout Northern Africa, the Mediterranean, Southern Europe and the Middle East. Our goal is to better define the 3D lithospheric shear-wave velocity structure within this region by improving the resolution of global surface wave tomographic studies. We hope to accomplish this goal by incorporating regional data at relatively short periods (less than 40 sec), into the regionalization of lateral velocity variation. Due to the sparse distributions of stations and earthquakes throughout the region (Figure 1) we have relied on data recorded at both teleseismic and regions; distances. Also, to date we have concentrated on Rayleigh wave group velocity measurements since valuable measurements can be made without knowledge of the source. In order to obtain Rayleigh wave group velocity throughout the region, vertical component teleseismic and regional seismograms were gathered from broadband, 3-component, digital MEDNET, GEOSCOPE and IRIS stations plus the portable PASSCAL deployment in Saudi Arabia. Figure 1 shows the distribution of earthquakes (black circles) and broadband digital seismic stations (white triangles) throughout southern Europe, the middle east and northern Africa used in this study. The most seismicly active regions of northern Africa are the Atlas mountains of Morocco and Algeria as well as the Red Sea region to the east. Significant seismicity also occurs in the Mediterranean, southern Europe and throughout the high mountains and plateaus of the middle-east. To date, over 1300 seismograms have been analyzed to determine the individual group velocities of 10-150 second Rayleigh waves. Travel times, for each period, are then inverted in a back projection tomographic method in order to determine the lateral group velocity variation throughout the region. These results are preliminary, however, Rayleigh wave group velocity maps for a range of

  3. Host Species Restriction of Middle East Respiratory Syndrome Coronavirus through Its Receptor, Dipeptidyl Peptidase 4

    PubMed Central

    van Doremalen, Neeltje; Miazgowicz, Kerri L.; Milne-Price, Shauna; Bushmaker, Trenton; Robertson, Shelly; Scott, Dana; Kinne, Joerg; McLellan, Jason S.; Zhu, Jiang

    2014-01-01

    ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012. Recently, the MERS-CoV receptor dipeptidyl peptidase 4 (DPP4) was identified and the specific interaction of the receptor-binding domain (RBD) of MERS-CoV spike protein and DPP4 was determined by crystallography. Animal studies identified rhesus macaques but not hamsters, ferrets, or mice to be susceptible for MERS-CoV. Here, we investigated the role of DPP4 in this observed species tropism. Cell lines of human and nonhuman primate origin were permissive of MERS-CoV, whereas hamster, ferret, or mouse cell lines were not, despite the presence of DPP4. Expression of human DPP4 in nonsusceptible BHK and ferret cells enabled MERS-CoV replication, whereas expression of hamster or ferret DPP4 did not. Modeling the binding energies of MERS-CoV spike protein RBD to DPP4 of human (susceptible) or hamster (nonsusceptible) identified five amino acid residues involved in the DPP4-RBD interaction. Expression of hamster DPP4 containing the five human DPP4 amino acids rendered BHK cells susceptible to MERS-CoV, whereas expression of human DPP4 containing the five hamster DPP4 amino acids did not. Using the same approach, the potential of MERS-CoV to utilize the DPP4s of common Middle Eastern livestock was investigated. Modeling of the DPP4 and MERS-CoV RBD interaction predicted the ability of MERS-CoV to bind the DPP4s of camel, goat, cow, and sheep. Expression of the DPP4s of these species on BHK cells supported MERS-CoV replication. This suggests, together with the abundant DPP4 presence in the respiratory tract, that these species might be able to function as a MERS-CoV intermediate reservoir. IMPORTANCE The ongoing outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) has caused 701 laboratory-confirmed cases to date, with 249 fatalities. Although bats and dromedary camels have been identified as potential MERS-CoV hosts, the virus has so far not been isolated from any species

  4. Depositional and structural evolution of the Middle Miocene depositional episode, east-central Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Combellas Bigott, Ricardo Ignacio

    Two widespread, transgressive deposits associated with the faunal top Amphistegina B (15.5 Ma) and Textularia W (12.1 Ma) define the Middle Miocene depositional episode. An extensive stratigraphic correlation framework established in this study allowed tracing of the middle Miocene sediment dispersal system from the shelf through the slope to the basin floor in the complex paleogeography of the east-central Gulf of Mexico. The Middle Miocene depositional episode is recorded in four genetic cycles (˜1 to 2 Ma), bounded by regional maximum flooding surfaces in the shelf and shelf margin setting, and three equivalent seismic sequences punctuated by condensed sections in the slope and basin floor. Two principal, long-lived extrabasinal fluvial/delta axes, the ancestral Mississippi and the Tennessee systems, provided the bulk of sediments that infilled the middle Miocene depocenters. Salt-related structural provinces controlled the configuration of the depocenters. Structural linked systems, dominated by gravity spreading, and a minibasin province, driven by differential subsidence, were established during the Middle Miocene depositional episode. Sediment supply coupled with wave energy flux, high-frequency sea-level changes, and salt tectonism determined the time and space distribution of progradation, aggradation, and retrogradation of system tracts. Middle Miocene shelf margins have prograded 20 to 40 miles from the relict lower Miocene shelf margin. Two depositional systems tracts characterize the constructional shelf margin: (1) a mixed-load fluvial-dominated platform delta/shelf-margin delta/delta-fed apron systems tract; and (2) a strandplain/shelf/muddy slope systems tract. However, the constructional, offlapping shelf margin systems were locally punctuated by a large-scale phase of retreat and erosion, named the Harang collapse system, in which a large volume of sediments bypassed the shelf margin to be deposited on the slope and basin floor. The Harang

  5. Receptor Variation and Susceptibility to Middle East Respiratory Syndrome Coronavirus Infection

    PubMed Central

    Barlan, Arlene; Zhao, Jincun; Sarkar, Mayukh K.; Li, Kun; McCray, Paul B.; Perlman, Stanley

    2014-01-01

    ABSTRACT The Middle East respiratory syndrome coronavirus (MERS-CoV) recently spread from an animal reservoir to infect humans, causing sporadic severe and frequently fatal respiratory disease. Appropriate public health and control measures will require discovery of the zoonotic MERS coronavirus reservoirs. The relevant animal hosts are liable to be those that offer optimal MERS virus cell entry. Cell entry begins with virus spike (S) protein binding to DPP4 receptors. We constructed chimeric DPP4 receptors that have the virus-binding domains of indigenous Middle Eastern animals and assessed the activities of these receptors in supporting S protein binding and virus entry. Human, camel, and horse receptors were potent and nearly equally effective MERS virus receptors, while goat and bat receptors were considerably less effective. These patterns reflected S protein affinities for the receptors. However, even the low-affinity receptors could hypersensitize cells to infection when an S-cleaving protease(s) was present, indicating that affinity thresholds for virus entry must be considered in the context of host-cell proteolytic environments. These findings suggest that virus receptors and S protein-cleaving proteases combine in a variety of animals to offer efficient virus entry and that several Middle Eastern animals are potential reservoirs for transmitting MERS-CoV to humans. IMPORTANCE MERS is a frequently fatal disease that is caused by a zoonotic CoV. The animals transmitting MERS-CoV to humans are not yet known. Infection by MERS-CoV requires receptors and proteases on host cells. We compared the receptors of humans and Middle Eastern animals and found that human, camel, and horse receptors sensitized cells to MERS-CoV infection more robustly than goat and bat receptors. Infection susceptibility correlated with affinities of the receptors for viral spike proteins. We also found that the presence of a cell surface lung protease greatly increases susceptibility

  6. Cobalt in north-east Pacific waters

    NASA Astrophysics Data System (ADS)

    Knauer, G. A.; Martin, J. H.; Gordon, R. M.

    1982-05-01

    Significant understanding has been gained recently about the biogeochemical cycling of trace metals in the ocean. This knowledge has mostly resulted from the accurate measurement of dissolved species in oceanic water columns. We report here that cobalt's vertical distribution is similar to that exhibited1-3 by Mn; that is, its surface enrichment/deep depletion (Fig. 1). However, amounts of Co (1-7 ng 1-1) are ~10-20 times less than those for Mn (Table 1), as might be expected from crustal abundance estimates4 for these elements (Mn=950; Co = 25 µg per g). The similarity between Mn and Co profiles implies the same biogeochemical pathways. The Co excess in nearshore surface waters probably results from continental weathering input processes, as suggested by the remarkable Co-salinity mirror-image relationship shown in Fig. 1, and the Co-salinity scatter diagram in Fig. 2a. The steady decrease in Co concentrations also indicates that Co is usually scavenged rather than regenerated at depth, as is the case with Mn (Fig. 1; Table 1).

  7. Analog models of convergence and divergence: perspectives of the tectonics of the Middle East

    NASA Astrophysics Data System (ADS)

    Mart, Yossi

    2010-05-01

    Three series of analog models of convergence and divergence of tectonic plates illuminate the possible tectonic processes that shaped the lithology of the Middle East since the early Miocene. The Mid-East geographic province extends from the Ionian Sea to the Arabian Sea, and comprises the Hellenic subduction zone, the Aegean back-arc basin, the motion of Anatolia southwestwards, the oblique collision of Arabia and Iran along the Zagros suture, and the continental break-up of the Gulf of Aden and the Red Sea. The tectonic evolution of all these diverse domains started in the Miocene nearly contemporaneously, and modeling suggests that the convergence and divergence, though derived from unrelated processes, their tectonics is intertwined. Centrifuge models of the initiation of subduction show the correlation between early subduction and the opening of its back-arc basin (Mart et al., 2005). The models emphasize the significance of extensive seawards roll-back of the deformation front when friction between the thrust slabs is reduced, and consequently, the pull within the overthrust slab that leads to its structural extension. That extension produced the Aegean domain with its volcanism and the exposure of its core complex, as well as the westwards displacement of Anatolia along the North and East Anatolian Faults. Sand-box models of oblique subduction, namely the gradual shift from subduction to collision along the convergence front, showed orthogonal patterns of extension in distal parts of the underthrust slab (Bellahsen et al., 2002). It is suggested that the extensional domains deflected the propagation of Carlsberg Ridge to swing 1200 and penetrate the Gulf of Aden in the early Miocene. The structural differences between the Gulf of Aden and the Red Sea can be accounted for by the results of sand-box experiments in oblique rifting (Mart and Dauteuil, 2000). The models suggest that oblique rifting, where the deviation from the normal extension was ca. 50, would

  8. 1. VIEW OF THE WATER PUMP (FEATURE B25), FACING EAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF THE WATER PUMP (FEATURE B-25), FACING EAST. PHOTO TAKEN FROM THE SEDIMENT DAM. - Nevada Lucky Tiger Mill & Mine, Water Pump, East slope of Buckskin Mountain, Paradise Valley, Humboldt County, NV

  9. Seismicity of the Earth 1900–2010 Middle East and vicinity

    USGS Publications Warehouse

    Jenkins, Jennifer; Turner, Bethan; Turner, Rebecca; Hayes, Gavin P.; Davies, Sian; Dart, Richard L.; Tarr, Arthur C.; Villaseñor, Antonio; Benz, Harley M.

    2013-01-01

    No fewer than four major tectonic plates (Arabia, Eurasia, India, and Africa) and one smaller tectonic block (Anatolia) are responsible for seismicity and tectonics in the Middle East and surrounding region. Geologic development of the region is a consequence of a number of first-order plate tectonic processes that include subduction, large-scale transform faulting, compressional mountain building, and crustal extension. In the east, tectonics are dominated by the collision of the India plate with Eurasia, driving the uplift of the Himalaya, Karakorum, Pamir and Hindu Kush mountain ranges. Beneath the Pamir‒Hindu Kush Mountains of northern Afghanistan, earthquakes occur to depths as great as 200 km as a result of remnant lithospheric subduction. Along the western margin of the India plate, relative motions between India and Eurasia are accommodated by strike-slip, reverse, and oblique-slip faulting, resulting in the complex Sulaiman Range fold and thrust belt, and the major translational Chaman Fault in Afghanistan. Off the south coasts of Pakistan and Iran, the Makran trench is the surface expression of active subduction of the Arabia plate beneath Eurasia. Northwest of this subduction zone, collision between the two plates forms the approximately 1,500-km-long fold and thrust belts of the Zagros Mountains, which cross the whole of western Iran and extend into northeastern Iraq. Tectonics in the eastern Mediterranean region are dominated by complex interactions between the Africa, Arabia, and Eurasia plates, and the Anatolia block. Dominant structures in this region include: the Red Sea Rift, the spreading center between the Africa and Arabia plates; the Dead Sea Transform, a major strike-slip fault, also accommodating Africa-Arabia relative motions; the North Anatolia Fault, a right-lateral strike-slip structure in northern Turkey accommodating much of the translational motion of the Anatolia block westwards with respect to Eurasia and Africa; and the Cyprian

  10. Medical Geology in the Middle East: Potential Health Risks from Mineralized Dust Exposure

    NASA Astrophysics Data System (ADS)

    Lyles, M. B.; Fredrickson, H. L.; Bednar, A. J.; Fannin, H. B.; Griffin, D. W.; Sobecki, T. M.

    2012-04-01

    In the Middle East, dust and sand storms are a persistent problem delivering significant amounts of mineralized particulates via inhalation into the mouth, nasal pharynx, and lungs. The health risks of this dust inhalation are presently being studied but accurate characterization as to the potential health effects is still lacking. Experiments were designed to study the chemical composition, mineral content, and microbial flora of Kuwaiti and Iraqi dust particles for the potential to cause adverse human health effects both acute and chronic. Multiple site samples were collected and chemical and physical characterization including particle size distribution and inorganic analysis was conducted, followed by analysis and identification of biologic flora to include bacteria, fungi and viruses. Additionally, PM10 exposure data was collected hourly over a 12 day period (>10,000 ug/m3). Data indicates that the mineralized dust is composed of calcium carbonate and magnesium sulfate coating over a precipitated matrix of metallic silicate nanocrystals of various forms containing a variety of trace and heavy metals constituting ~3 % of the particles by weight. This includes ~ 1% by weight bioaccessible aluminum and reactive iron with the remaining 1% a mixture of bioaccessible trace and heavy metals. Microbial analysis reveals a significant biodiversity of bacteria of which ~25 % are known pathogens. Of the microbes identified, several have hemolytic properties and most have significant antibiotic resistance. Viral analysis indicates a tremendous amount of virons with a large percent of RNA viruses. The level of total suspended particle mass at PM10 constitutes an excessive exposure micro-particulates including PM 2.5 (~1,0000 ug/m3). Reported data on cell culture and animal studies have indicated a high level of toxicity to these dust particles. Taken together, these data suggest that at the level of dust exposure commonly found in the Middle East (i.e., Iraq, Kuwait, and

  11. Middle East Desert Dust Exposure: Health Risks from Metals and Microbial Pathogens

    NASA Astrophysics Data System (ADS)

    Lyles, M. B.

    2014-12-01

    In the Middle East, dust and sand storms are a persistent problem and can deliver significant amounts of micro-particulates via inhalation into the mouth, nasal pharynx, & lungs due to the fine size and abundance of these micro-particulates. The chronic and acute health risks of this dust inhalation have not been well studied nor has the dust been effectively characterized as to its chemical composition, mineral content, or microbial flora. Scientific experiments were designed to study the Kuwaiti and Iraqi dust as to its physical, chemical, and biological characteristics and for its potential to cause adverse health effects. First, dust samples from different locations were collected and processed and exposure data collected. Initial chemical and physical characterization of each sample including particle size distribution and inorganic analysis was conducted, followed by characterization of biologic flora of the dust, including bacteria, fungi and viruses. Data indicates that the mineralized dust is composed of calcium carbonate over a matrix of metallic silicate nanocrystals containing a variety of trace and heavy metals constituting ~3 % of the PM10 particles by weight, of which ~1% is bioaccessible aluminum and reactive iron, each. The particles also consist of ~1% bioavailable aluminum and reactive iron each. Microbial analysis reveals a significant biodiversity of bacterial, fungi, and viruses of which ~30% are known pathogens. Of the microbes identified, several have hemolytic properties and most have significant antibiotic resistance. Viral analysis indicates a tremendous amount of virons with a large percent of RNA viruses. The level of total suspended particle mass at PM 10 along with environmental & physiological conditions present constitute an excessive exposure to micro-particulates including PM 2.5 and the potential for adverse health effects. Reported data on cell culture and animal studies have indicated a high level of toxicity to these dust

  12. Future of Management of Multiple Sclerosis in the Middle East: A Consensus View from Specialists in Ten Countries

    PubMed Central

    Aljumah, Mohammed; Alsharoqi, I.; Bohlega, Saeed A.; Dahdaleh, Maurice; Deleu, Dirk; Esmat, Khaled; Khalifa, Ahmad; Sahraian, Mohammad A.; Szólics, Miklós; AlTahan, Abdulrahman; Yamout, Bassem I.; Rieckmann, Peter

    2013-01-01

    The prevalence of multiple sclerosis (MS) is now considered to be medium-to-high in the Middle East and is rising, particularly among women. While the characteristics of the disease and the response of patients to disease-modifying therapies are generally comparable between the Middle East and other areas, significant barriers to achieving optimal care for MS exist in these developing nations. A group of physicians involved in the management of MS in ten Middle Eastern countries met to consider the future of MS care in the region, using a structured process to reach a consensus. Six key priorities were identified: early diagnosis and management of MS, the provision of multidisciplinary MS centres, patient engagement and better communication with stakeholders, regulatory body education and reimbursement, a commitment to research, and more therapy options with better benefit-to-risk ratios. The experts distilled these priorities into a single vision statement: “Optimization of patient-centred multidisciplinary strategies to improve the quality of life of people with MS.” These core principles will contribute to the development of a broader consensus on the future of care for MS in the Middle East. PMID:24455267

  13. Future of management of multiple sclerosis in the middle East: a consensus view from specialists in ten countries.

    PubMed

    Aljumah, Mohammed; Alroughani, Raed; Alsharoqi, I; Bohlega, Saeed A; Dahdaleh, Maurice; Deleu, Dirk; Esmat, Khaled; Khalifa, Ahmad; Sahraian, Mohammad A; Szólics, Miklós; Altahan, Abdulrahman; Yamout, Bassem I; Rieckmann, Peter; Daif, Abdulkader

    2013-01-01

    The prevalence of multiple sclerosis (MS) is now considered to be medium-to-high in the Middle East and is rising, particularly among women. While the characteristics of the disease and the response of patients to disease-modifying therapies are generally comparable between the Middle East and other areas, significant barriers to achieving optimal care for MS exist in these developing nations. A group of physicians involved in the management of MS in ten Middle Eastern countries met to consider the future of MS care in the region, using a structured process to reach a consensus. Six key priorities were identified: early diagnosis and management of MS, the provision of multidisciplinary MS centres, patient engagement and better communication with stakeholders, regulatory body education and reimbursement, a commitment to research, and more therapy options with better benefit-to-risk ratios. The experts distilled these priorities into a single vision statement: "Optimization of patient-centred multidisciplinary strategies to improve the quality of life of people with MS." These core principles will contribute to the development of a broader consensus on the future of care for MS in the Middle East.

  14. Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection.

    PubMed

    Musallam, I I; Abo-Shehada, M N; Hegazy, Y M; Holt, H R; Guitian, F J

    2016-03-01

    A systematic review of studies providing frequency estimates of brucellosis in humans and ruminants and risk factors for Brucella spp. seropositivity in humans in the Middle East was conducted to collate current knowledge of brucellosis in this region. Eight databases were searched for peer-reviewed original Arabic, English, French and Persian journal articles; the search was conducted on June 2014. Two reviewers evaluated articles for inclusion based on pre-defined criteria. Of 451 research articles, only 87 articles passed the screening process and provided bacteriological and serological evidence for brucellosis in all Middle Eastern countries. Brucella melitensis and B. abortus have been identified in most countries in the Middle East, supporting the notion of widespread presence of Brucella spp. especially B. melitensis across the region. Of the 87 articles, 49 were used to provide evidence of the presence of Brucella spp. but only 11 provided new knowledge on the frequency of brucellosis in humans and ruminants or on human risk factors for seropositivity and were deemed of sufficient quality. Small ruminant populations in the region show seroprevalence values that are among the highest worldwide. Human cases are likely to arise from subpopulations occupationally exposed to ruminants or from the consumption of unpasteurized dairy products. The Middle East is in need of well-designed observational studies that could generate reliable frequency estimates needed to assess the burden of disease and to inform disease control policies.

  15. Confidentiality, informed consent, and children's participation in research involving stored tissue samples: interviews with medical professionals from the Middle East.

    PubMed

    Alahmad, Ghiath; Al Jumah, Mohammed; Dierickx, Kris

    2015-01-01

    Ethical issues regarding research biobanks continue to be a topic of intense debate, especially issues of confidentiality, informed consent, and child participation. Although considerable empirical literature concerning research biobank ethics exists, very little information is available regarding the opinions of medical professionals doing genetics research from the Middle East, especially Arabic speaking countries. Ethical guidelines for research biobanks are critically needed as some countries in the Middle East are starting to establish national research biobanks. Islam is the dominant religion in these countries, and it affects people's behavior and influences their positions. Moreover, communities in these countries enjoy a set of customs, traditions and social norms, and have social and familial structures that must be taken into account when developing research policies. We interviewed 12 medical professionals from the Middle East currently working with stored tissue samples to document their opinions. We found general agreement. Participants' primary concerns were similar to the views of researchers internationally. Since children tend to represent a high percentage of Middle Eastern populations, and because children's bodies are not just small adult bodies, the interviewed professionals strongly believed that it is imperative to include children in biobank research. Participants generally believed that protecting confidentiality is socially very important and that informed consent/assent must be obtained from both adult and child participants. This study provides a starting point for additional studies.

  16. Capacity Building and Financing Oral Health in the African and Middle East Region.

    PubMed

    Mumghamba, E G; Joury, E; Fatusi, O; Ober-Oluoch, J; Onigbanjo, R J; Honkala, S

    2015-07-01

    Many low- and middle-income countries do not yet have policies to implement effective oral health programs. A reason is lack of human and financial resources. Gaps between resource needs and available health funding are widening. By building capacity, countries aim to improve oral health through actions by oral health care personnel and oral health care organizations and their communities. Capacity building involves achieving measurable and sustainable results in training, research, and provision of care. Actions include advancement of knowledge, attitudes and skills, expansion of support, and development of cohesiveness and partnerships. The aim of this critical review is to review existing knowledge and identify gaps and variations between and within different income levels in relation to the capacity building and financing oral health in the African and Middle East region (AMER). A second aim is to formulate research priorities and outline a research agenda for capacity building and financing to improve oral health and reduce oral health inequalities in the AMER. The article focuses on capacity building for oral health and oral health financing in the AMER of the IADR. In many communities in the AMER, there are clear and widening gaps between the dental needs and the existing capacity to meet these needs in terms of financial and human resources. Concerted efforts are required to improve access to oral health care through appropriate financing mechanisms, innovative health insurance schemes, and donor support and move toward universal oral health care coverage to reduce social inequality in the region. It is necessary to build capacity and incentivize the workforce to render evidence-based services as well as accessing funds to conduct research on equity and social determinants of oral health while promoting community engagement and a multidisciplinary approach.

  17. Identification and Treatment of Patients with Homozygous Familial Hypercholesterolaemia: Information and Recommendations from a Middle East Advisory Panel.

    PubMed

    Al-Ashwal, Abdullah; Alnouri, Fahad; Sabbour, Hani; Al-Mahfouz, Abdulraof; Al-Sayed, Nasreen; Razzaghy-Azar, Maryam; Al-Allaf, Faisal; Al-Waili, Khalid; Banerjee, Yajnavalka; Genest, Jacques; Santos, Raul D; Al-Rasadi, Khalid

    2015-01-01

    We present clinical practice guidelines for the diagnosis and treatment of homozygous familial hypercholesterolaemia (HoFH) in the Middle East region. While guidelines are broadly applicable in Europe, in the Middle East we experience a range of confounding factors that complicate disease management to a point whereby the European guidance cannot be applied without significant modification. Specifically, for disease prevalence, the Middle East region has an established epidemic of diabetes and metabolic syndrome that can complicate treatment and mask a clinical diagnosis of HoFH. We have also a high incidence of consanguineous marriages, which increase the risk of transmission of recessive and homozygous genetic disorders. This risk is further augmented in autosomal dominant disorders such as familial hypercholesterolaemia (FH), in which a range of defective genes can be transmitted, all of which contribute to the phenotypic expression of the disease. In terms of treatment, we do not have access to lipoprotein apheresis on the same scale as in Europe, and there remains a significant reliance on statins, ezetimibe and the older plasma exchange methods. Additionally, we do not have widespread access to anti-apolipoprotein B therapies and microsomal transfer protein inhibitors. In order to adapt existing global guidance documents on HoFH to the Middle East region, we convened a panel of experts from Oman, Saudi Arabia, UAE, Iran and Bahrain to draft a regional guidance document for HoFH. We also included selected experts from outside the region. This panel statement will form the foundation of a detailed appraisal of the current FH management in the Middle Eastern population and thereby provide a suitable set of guidelines tailored for the region. PMID:26311574

  18. Supporting Hospital Doctors in the Middle East by Email Telemedicine: Something the Industrialized World Can Do to Help

    PubMed Central

    Patterson, Victor; Swinfen, Pat; Swinfen, Roger; Azzo, Emil; Taha, Husen

    2007-01-01

    Background Since 1999, the Swinfen Charitable Trust has operated an email referral system between doctors in the developing world and specialists in the industrialized world. Since 2001, it has expanded its operation into the Middle East, in particular Iraq, an area of considerable conflict. Objectives The aim was to compare referral patterns to the Trust from the Middle East with those received from the rest of the developing world and to look for qualitative evidence of health gain. Methods We analyzed referrals to the Swinfen Charitable Trust between July 2004 and June 2007 and compared these by speciality with those received from elsewhere during the same 3-year period. We asked two referring doctors for their views of the process, and we analyzed the total Middle Eastern referrals made to a single specialty (neurology). Results Between July 2004 and June 2007, 283 referrals were received from four countries in the Middle East (Iraq, Afghanistan, Pakistan, Kuwait) and 500 cases were received from 22 other countries. The 283 cases resulted in 522 separate queries to specialists. The median time to specialist reply for the queries relating to the 283 Middle Eastern cases was 24.3 hours (interquartile range 6.1-63.3). There was a significant difference in case mix between the Middle East and the rest of the world (P < .001), with more obstetric referrals and fewer referrals in medical specialties and radiology. The referring doctors were helped greatly by the service. The neurologist was confident of the diagnosis in 20 of 26 referrals received (77%). Both referring doctors and the specialist were able to cite referred cases where management was improved as a result of the service. Conclusions Email telemedicine can be used in areas of conflict such as the Middle East. Perhaps surprisingly, trauma referrals are not increased but obstetric referrals are. Supporting individual doctor-patient encounters in this way is therefore often beneficial and is easily

  19. [Responses of functional diversity of aquatic insect community to land use change in middle reach of Qiantang River, East China].

    PubMed

    Zhang, Lian-Bo; Liu, Dong-Xiao; Liu, Shuo-Ru; Zhang, Yong; Tong, Xiao-Li; Wang, Bei-Xin

    2013-10-01

    Based on the biological traits such as life history, resistance ability against environmental disturbance, and physiological characteristics of aquatic insects, and by using the fourth-corner statistical method, this paper studied the responses of the functional diversity of aquatic insect community to land use change in the middle reach of Qiantang River, Zhejiang Province of East China. For the test aquatic insect community, some of its biological traits were sensitive to land use change, and altered along human disturbance gradients as expected. With the increasing intensity of human disturbance, the maximal insect body length decreased gradually, the dominant respiration pattern evolved from gill respiration to tegument respiration, and the abundance of burrowers increased significantly. At the same time, the functional diversity measured as Rao's quadratic entropy was significantly higher in reference sites than in disturbed sites (P < 0.001), demonstrating that the changes in the functional diversity of the aquatic community were mainly induced by the land use change caused by human activities, which resulted in the decline of stream water quality and habitat quality and the variations of aquatic insect community composition and biological traits. The aquatic insect biological traits and functional diversity could be the potentially effective indicators in the stream health assessment in the future.

  20. Silurian shale origin for light oil, condensate, and gas in Algeria and the Middle East

    SciTech Connect

    Zumberge, J.E. ); Macko, S. ) Engel, M. )

    1996-01-01

    Two of the largest gas fields in the world, Hasi R'Mel, Algeria and North Dome, Qatar, also contain substantial condensate and light oil reserves. Gas to source rock geochemical correlation is difficult due to the paucity of molecular parameters in the former although stable isotope composition is invaluable. However, by correlating source rocks with light oils and condensates associated with gas production using traditional geochemical parameters such as biomarkers and isotopes, a better understanding of the origin of the gas is achieved. Much of the crude oil in the Ghadames/Illizi Basins of Algeria has long been thought to have been generated from Silurian shales. New light oil discoveries in Saudi Arabia have also been shown to originate in basal euxinic Silurian shales. Key sterane and terpane biomarkers as well as the stable carbon isotopic compositions of the C15+ saturate and aromatic hydrocarbon fractions allow for the typing of Silurian-sourced, thermally mature light oils in Algeria and the Middle East. Even though biomarkers are often absent due to advanced thermal maturity, condensates can be correlated to the light oils using (1) carbon isotopes of the residual heavy hydrocarbon fractions, (2) light hydrocarbon distributions (e.g., C7 composition), and (3) compound specific carbon isotopic composition of the light hydrocarbons. The carbon isotopes of the C2-C4 gas components ran then be compared to the associated condensate and light oil isotopic composition.

  1. Silurian shale origin for light oil, condensate, and gas in Algeria and the Middle East

    SciTech Connect

    Zumberge, J.E.; Macko, S. Engel, M.

    1996-12-31

    Two of the largest gas fields in the world, Hasi R`Mel, Algeria and North Dome, Qatar, also contain substantial condensate and light oil reserves. Gas to source rock geochemical correlation is difficult due to the paucity of molecular parameters in the former although stable isotope composition is invaluable. However, by correlating source rocks with light oils and condensates associated with gas production using traditional geochemical parameters such as biomarkers and isotopes, a better understanding of the origin of the gas is achieved. Much of the crude oil in the Ghadames/Illizi Basins of Algeria has long been thought to have been generated from Silurian shales. New light oil discoveries in Saudi Arabia have also been shown to originate in basal euxinic Silurian shales. Key sterane and terpane biomarkers as well as the stable carbon isotopic compositions of the C15+ saturate and aromatic hydrocarbon fractions allow for the typing of Silurian-sourced, thermally mature light oils in Algeria and the Middle East. Even though biomarkers are often absent due to advanced thermal maturity, condensates can be correlated to the light oils using (1) carbon isotopes of the residual heavy hydrocarbon fractions, (2) light hydrocarbon distributions (e.g., C7 composition), and (3) compound specific carbon isotopic composition of the light hydrocarbons. The carbon isotopes of the C2-C4 gas components ran then be compared to the associated condensate and light oil isotopic composition.

  2. Strengthening epidemiologic investigation of infectious diseases in Korea: lessons from the Middle East Respiratory Syndrome outbreak

    PubMed Central

    Lee, Changhwan; Ki, Moran

    2015-01-01

    The recent outbreak of Middle East Respiratory Syndrome (MERS) coronavirus infection in Korea resulted in large socioeconomic losses. This provoked the Korean government and the general public to recognize the importance of having a well-established system against infectious diseases. Although epidemiologic investigation is one of the most important aspects of prevention, it has been pointed out that much needs to be improved in Korea. We review here the current status of the Korean epidemiologic service and suggest possible supplementation measures. We examine the current national preventive infrastructure, including human resources such as Epidemic Intelligence Service officers, its governmental management, and related policies. In addition, we describe the practical application of these resources to the recent MERS outbreak and the progress in preventive measures. The spread of MERS demonstrated that the general readiness for emerging infectious diseases in Korea is considerably low. We believe that it is essential to increase society’s investment in disease prevention. Fostering public health personnel, legislating management policies, and establishing research centers for emerging infectious diseases are potential solutions. Evaluating international preventive systems, developing cooperative measures, and initiating improvements are necessary. We evaluated the Korean epidemiologic investigation system and the public preventive measures against infectious diseases in light of the recent MERS outbreak. We suggest that governmental authorities in Korea enforce preventive policies, foster the development of highly qualified personnel, and increase investment in the public health domain of infectious disease prevention. PMID:26493654

  3. High correlation of Middle East respiratory syndrome spread with Google search and Twitter trends in Korea.

    PubMed

    Shin, Soo-Yong; Seo, Dong-Woo; An, Jisun; Kwak, Haewoon; Kim, Sung-Han; Gwack, Jin; Jo, Min-Woo

    2016-09-06

    The Middle East respiratory syndrome coronavirus (MERS-CoV) was exported to Korea in 2015, resulting in a threat to neighboring nations. We evaluated the possibility of using a digital surveillance system based on web searches and social media data to monitor this MERS outbreak. We collected the number of daily laboratory-confirmed MERS cases and quarantined cases from May 11, 2015 to June 26, 2015 using the Korean government MERS portal. The daily trends observed via Google search and Twitter during the same time period were also ascertained using Google Trends and Topsy. Correlations among the data were then examined using Spearman correlation analysis. We found high correlations (>0.7) between Google search and Twitter results and the number of confirmed MERS cases for the previous three days using only four simple keywords: "MERS", " ("MERS (in Korean)"), " ("MERS symptoms (in Korean)"), and " ("MERS hospital (in Korean)"). Additionally, we found high correlations between the Google search and Twitter results and the number of quarantined cases using the above keywords. This study demonstrates the possibility of using a digital surveillance system to monitor the outbreak of MERS.

  4. Increased seasonality in Middle East temperatures during the last interglacial period.

    PubMed

    Felis, Thomas; Lohmann, Gerrit; Kuhnert, Henning; Lorenz, Stephan J; Scholz, Denis; Pätzold, Jürgen; Al-Rousan, Saber A; Al-Moghrabi, Salim M

    2004-05-13

    The last interglacial period (about 125,000 years ago) is thought to have been at least as warm as the present climate. Owing to changes in the Earth's orbit around the Sun, it is thought that insolation in the Northern Hemisphere varied more strongly than today on seasonal timescales, which would have led to corresponding changes in the seasonal temperature cycle. Here we present seasonally resolved proxy records using corals from the northernmost Red Sea, which record climate during the last interglacial period, the late Holocene epoch and the present. We find an increased seasonality in the temperature recorded in the last interglacial coral. Today, climate in the northern Red Sea is sensitive to the North Atlantic Oscillation, a climate oscillation that strongly influences winter temperatures and precipitation in the North Atlantic region. From our coral records and simulations with a coupled atmosphere-ocean circulation model, we conclude that a tendency towards the high-index state of the North Atlantic Oscillation during the last interglacial period, which is consistent with European proxy records, contributed to the larger amplitude of the seasonal cycle in the Middle East.

  5. Calibration of Regional Seismic Stations in the Middle East with Shots in Turkey

    SciTech Connect

    Toksoz, M N; Kuleli, S; Gurbuz, C; Kalafat, D; Nekler, T; Zor, K; Yilmazer, M; Ogutcu, Z; Schultz, C A; Harris, D B

    2003-07-21

    The objective of this project is to calibrate regional travel-times and propagation characteristics of seismic waves in Turkey and surrounding areas in the Middle East in order to enhance detection and location capabilities in the region. Important data for the project will be obtained by large calibration shots in central and eastern Turkey. The first, a two-ton shot, was fired in boreholes near Keskin in central Anatolia on 23 November 2002. The explosives were placed in 14 holes, each 80 m deep, arranged in concentric circular arrays. Ninety temporary seismic stations were deployed within a 300 km radius around the shot. The permanent stations of the Turkish National Seismic Network provided a good azimuthal coverage as well as three radial traverses. Most stations within a radius of 200 km recorded the shot. Travel-time data have been analyzed to obtain a detailed crustal model under the shot and along the profiles. The model gives a 35 km thick crust, characterized by two layers with velocities of 5.0 and 6.4 km/s. The P{sub n} velocity was found to be 7.8 km/s. The crustal thickness decreases to the north where the profile crosses the North Anatolian fault. There is a slight increase in crustal velocities, but no change in crustal thickness to the west. Data analysis effort is continuing to refine the regional velocity models and to obtain station corrections.

  6. Standard and AEGIS nicking molecular beacons detect amplicons from the Middle East respiratory syndrome coronavirus.

    PubMed

    Yaren, Ozlem; Glushakova, Lyudmyla G; Bradley, Kevin M; Hoshika, Shuichi; Benner, Steven A

    2016-10-01

    This paper combines two advances to detect MERS-CoV, the causative agent of Middle East Respiratory Syndrome, that have emerged over the past few years from the new field of "synthetic biology". Both are based on an older concept, where molecular beacons are used as the downstream detection of viral RNA in biological mixtures followed by reverse transcription PCR amplification. The first advance exploits the artificially expanded genetic information systems (AEGIS). AEGIS adds nucleotides to the four found in standard DNA and RNA (xNA); AEGIS nucleotides pair orthogonally to the A:T and G:C pairs. Placing AEGIS components in the stems of molecular beacons is shown to lower noise by preventing unwanted stem invasion by adventitious natural xNA. This should improve the signal-to-noise ratio of molecular beacons operating in complex biological mixtures. The second advance introduces a nicking enzyme that allows a single target molecule to activate more than one beacon, allowing "signal amplification". Combining these technologies in primers with components of a self-avoiding molecular recognition system (SAMRS), we detect 50 copies of MERS-CoV RNA in a multiplexed respiratory virus panel by generating fluorescence signal visible to human eye and/or camera. PMID:27421627

  7. Avoiding student infection during a Middle East respiratory syndrome (MERS) outbreak: a single medical school experience

    PubMed Central

    2016-01-01

    Purpose: In outbreaks of infectious disease, medical students are easily overlooked in the management of healthcare personnel protection although they serve in clinical clerkships in hospitals. In the early summer of 2015, Middle East respiratory syndrome (MERS) struck South Korea, and students of Sungkyunkwan University School of Medicine (SKKUSOM) were at risk of contracting the disease. The purpose of this report is to share SKKUSOM’s experience against the MERS outbreak and provide suggestions for medical schools to consider in the face of similar challenges. Methods: Through a process of reflection-on-action, we examined SKKUSOM’s efforts to avoid student infection during the MERS outbreak and derived a few practical guidelines that medical schools can adopt to ensure student safety in outbreaks of infectious disease. Results: The school leadership conducted ongoing risk assessment and developed contingency plans to balance student safety and continuity in medical education. They rearranged the clerkships to another hospital and offered distant lectures and tutorials. Five suggestions are extracted for medical schools to consider in infection outbreaks: instant cessation of clinical clerkships; rational decision making on a school closure; use of information technology; constant communication with hospitals; and open communication with faculty, staff, and students. Conclusion: Medical schools need to take the initiative and actively seek countermeasures against student infection. It is essential that medical schools keep constant communication with their index hospitals and the involved personnel. In order to assure student learning, medical schools may consider offering distant education with online technology. PMID:27240893

  8. Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants

    DOE PAGESBeta

    Borucki, Monica K.; Lao, Victoria; Hwang, Mona; Gardner, Shea; Adney, Danielle; Munster, Vincent; Bowen, Richard; Allen, Jonathan E.

    2016-01-20

    Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging human pathogen related to SARS virus. In vitro studies indicate this virus may have a broad host range suggesting an increased pandemic potential. Genetic and epidemiological evidence indicate camels serve as a reservoir for MERS virus but the mechanism of cross species transmission is unclear and many questions remain regarding the susceptibility of humans to infection. Deep sequencing data was obtained from the nasal samples of three camels that had been experimentally infected with a human MERS-CoV isolate. A majority of the genome was covered and average coverage was greater thanmore » 12,000x depth. Although only 5 mutations were detected in the consensus sequences, 473 intrahost single nucleotide variants were identified. Lastly, many of these variants were present at high frequencies and could potentially influence viral phenotype and the sensitivity of detection assays that target these regions for primer or probe binding.« less

  9. Preliminary maps of crustal thickness and regional seismic phases for the Middle East and North Africa

    SciTech Connect

    Sweeney, J.J.

    1995-09-06

    As part of the development of regional seismic discrimination methods for the Middle East and North Africa (MENA) the author is building a database of information related to seismic propagation and crustal structure as well as associated geologic-tectonic and geophysical data. He hopes to use these data to construct and test models of regional seismic propagation and evaluate various detection/discrimination scenarios. To date, the database has been developed by building on a list of references for MENA provided by the Institute for the Study of the Continents (INSTOC) at Cornell University. To this list the author has added an equal number of references resulting from his own literature search which has emphasized papers dealing with seismicity and regional and teleseismic phase data. This paper represents an initial attempt to consolidate some of the information from the database into a form useful to researchers modeling regional seismic waveforms. The information compiled in this report is supplemental to the INSTOC database and has not been compiled anywhere else. What follows is a series of maps which illustrate the spatial variation of seismic phase velocities and crustal thickness. The text identifies the sources of information used in the map preparation. Data for the compilation of these maps has come from an initial search of the database as it presently exists and is not intended to be exhaustive. The author hopes that this initial exercise will help to identify areas and types of data that are deficient and help to focus future data gathering activities.

  10. A Comparative Review of Animal Models of Middle East Respiratory Syndrome Coronavirus Infection.

    PubMed

    Baseler, L; de Wit, E; Feldmann, H

    2016-05-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) was initially isolated from a Saudi Arabian man with fatal pneumonia. Since the original case in 2012, MERS-CoV infections have been reported in >1500 humans, and the case fatality rate is currently 35%. This lineage C betacoronavirus has been reported to cause a wide range of disease severity in humans, ranging from asymptomatic to progressive fatal pneumonia that may be accompanied by renal or multiorgan failure. Although the clinical presentation of human MERS-CoV infection has been documented, many facets of this emerging disease are still unknown and could be studied with animal models. Several animal models of MERS-CoV have been developed, including New Zealand white rabbits, transduced or transgenic mice that express human dipeptidyl peptidase 4, rhesus macaques, and common marmosets. This review provides an overview of the current state of knowledge on human MERS-CoV infections, the probable origin of MERS-CoV, and the available animal models of MERS-CoV infection. Evaluation of the benefits and limitations of these models will aid in appropriate model selection for studying viral pathogenesis and transmission, as well as for testing vaccines and antivirals against MERS-CoV.

  11. An Acute Immune Response to Middle East Respiratory Syndrome Coronavirus Replication Contributes to Viral Pathogenicity.

    PubMed

    Baseler, Laura J; Falzarano, Darryl; Scott, Dana P; Rosenke, Rebecca; Thomas, Tina; Munster, Vincent J; Feldmann, Heinz; de Wit, Emmie

    2016-03-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in a human with severe pneumonia in 2012. Since then, infections have been detected in >1500 individuals, with disease severity ranging from asymptomatic to severe, fatal pneumonia. To elucidate the pathogenesis of this virus and investigate mechanisms underlying disease severity variation in the absence of autopsy data, a rhesus macaque and common marmoset model of MERS-CoV disease were analyzed. Rhesus macaques developed mild disease, and common marmosets exhibited moderate to severe, potentially lethal, disease. Both nonhuman primate species exhibited respiratory clinical signs after inoculation, which were more severe and of longer duration in the marmosets, and developed bronchointerstitial pneumonia. In marmosets, the pneumonia was more extensive, with development of severe airway lesions. Quantitative analysis showed significantly higher levels of pulmonary neutrophil infiltration and higher amounts of pulmonary viral antigen in marmosets. Pulmonary expression of the MERS-CoV receptor, dipeptidyl peptidase 4, was similar in marmosets and macaques. These results suggest that increased virus replication and the local immune response to MERS-CoV infection likely play a role in pulmonary pathology severity. Together, the rhesus macaque and common marmoset models of MERS-CoV span the wide range of disease severity reported in MERS-CoV-infected humans, which will aid in investigating MERS-CoV disease pathogenesis. PMID:26724387

  12. Stray animal populations and public health in the South Mediterranean and the Middle East regions.

    PubMed

    Seimenis, Aristarhos; Tabbaa, Darem

    2014-01-01

    Uncontrolled urban growth in South Mediterranean and the Middle East regions involves city dwellers and stray animals (mainly dogs and cats) creating a dense and downgraded environment, in which irregular street garbage collection disposes sufficient food for survival and proliferation of stray animals. Under such conditions serious public health hazards are expected due to the increase of animal bites, the multiplication of insects and rodents vectors of different viral, bacterial, fungal and parasitic agents to which humans are exposed. Traditional national stray animal eradication programs and occasional small animals' humane elimination campaigns are insufficient to avert human and veterinary health risks when not coupled with modern technologies. In such environments, multiple foci of emerging and re-emerging zoonoses easily spread, i.e. rabies, hydatidosis, leishmaniasis and toxoplasmosis. Upgrading urban and peri-urban situations requires integrated/coordinated management programmes, in which public and animal health services as well as municipalities have a crucial role. Control and upgrading programmes should be flexible and able to adapt to the specific conditions of the given country/region. In this context, intersectoral/interprofessional collaborations and community participation are crucial for any national and regional development strategies. In this respect, a global approach considering both public health and socio-economic problems shows to be extremely adequate and effective.

  13. Review of subtribe Singilina Jeannel, 1949, of the Middle East and Central Asia (Coleoptera, Carabidae, Lebiini)

    PubMed Central

    Anichtchenko, Alexander

    2011-01-01

    Abstract Species of the genus Singilis Rambur, 1837 (Phloeozeteus Peyron, 1856, syn. n., Agatus Motschulsky, 1845, syn. n.), occurring in the Middle East and Central Asia are reviewed, with 24 species now recognized in the region, including ten species described as new: Singilis makarovi sp. n. (Tajikistan), Singilis jedlickai sp. n. (Afghanistan), Singilis kolesnichenkoi sp. n. (Iran), Singilis kabakovi sp. n. (Afghanistan, Iran), Singilis timuri sp. n. (Uzbekistan), Singilis klimenkoi sp. n. (Iran), Singilis saeedi sp. n. (Iran), Singilis felixi sp. n. (UAE), Singilis kryzhanovskii sp. n. (Iran, Turkmenistan), and Singilis timidus sp. n. (Iran); Singilis libani (Sahlberg, 1913) is recognized as a valid species; and Singilis solskyi nom. n. is proposed as a replacement name for Agatus bicolor (Solsky, 1874, not Rambur 1837), now placed in Singilis as junior homonym. New synonymies include: Singilis cingulatus (Gebler, 1843) = Singilis jakeschi Jedlička, 1967, syn. n.; Singilis mesopotamicus Pic, 1901 = Singilis apicalis Jedlička, 1956, syn. n. A key to species is provided. Habitus and aedeagal illustrations are provided for all species. Distributional data include many new country records. PMID:22291510

  14. Diversity of Cronobacter spp. isolates from the vegetables in the middle-east coastline of China.

    PubMed

    Chen, Wanyi; Yang, Jielin; You, Chunping; Liu, Zhenmin

    2016-06-01

    Cronobacter spp. has caused life-threatening neonatal infections mainly resulted from consumption of contaminated powdered infant formula. A total of 102 vegetable samples from retail markets were evaluated for the presence of Cronobacter spp. Thirty-five presumptive Cronobacter isolates were isolated and identified using API 20E and 16S rDNA sequencing analyses. All isolates and type strains were characterized using enterobacterial repetitive intergenic consensus sequence PCR (ERIC-PCR), and genetic profiles of cluster analysis from this molecular typing test clearly showed that there were differences among isolates from different vegetables. A polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) based on the amplification of the gyrB gene (1258 bp) was developed to differentiate among Cronobacter species. A new PCR-RFLP assay based on the amplification of the gyrB gene using Alu I and Hinf I endonuclease combination is established and it has been confirmed an accurate and rapid subtyping method to differentiate Cronobacter species. Sequence analysis of the gyrB gene was proven to be suitable for the phylogenetic analysis of the Cronobacter strains, which has much better resolution based on SNPs in the identification of Cronobacter species specificity than PCR-RFLP and ERIC-PCR. Our study further confirmed that vegetables are one of the most common habitats or sources of Cronobacter spp. contamination in the middle-east coastline of China.

  15. Molecular typing of Vibrio parahaemolyticus isolates from the middle-east coastline of China.

    PubMed

    Chen, Wanyi; Xie, Yanping; Xu, Jingye; Wang, Qingzhong; Gu, Ming; Yang, Jielin; Zhou, Min; Wang, Dapeng; Shi, Chunlei; Shi, Xianming

    2012-02-15

    The occurrence of outbreaks of Vibrio parahaemolyticus gastroenteritis in China highlights the need for strain characterization and subtyping of this pathogenic species. A total of 56 epidemiologically-unrelated strains of V. parahaemolyticus were isolated from clinical samples, seafood and various environmental sites in the middle-east coastline of China from 2006 to 2008. The isolates were characterized using four molecular typing methods, including ribotyping, enterobacterial repetitive intergenic consensus sequence PCR (ERIC-PCR), pulsed-field gel electrophoresis (PFGE), and sequence analysis of the gyrB gene. Genetic profiles of cluster analysis from these molecular typing tests clearly showed that there were differences in potential pathogenicity among isolates from seafood and its environments. Genetic characterization of two isolates (F13 and QS2) that originated from seafood demonstrated that they were potentially pathogenic. Discriminatory indices of four typing methods for the 56 V. parahaemolyticus isolates were differentiated by Simpson's Index of Diversity. The discriminatory index of ERIC-PCR typing was maximal (D=0.942), while that of sequence analysis of the gyrB gene was minimal (D=0.702). The discriminatory ability was greatly enhanced (D=0.966) when ERIC-PCR was coupled with sequence analysis of the gyrB gene. These results suggest that ERIC-PCR combined with sequence analysis of gyrB gene may be a reliable, rapid typing strategy for V. parahaemolyticus strains.

  16. Assessment of the awareness level of dental students toward Middle East Respiratory Syndrome-coronavirus

    PubMed Central

    Kharma, Mohamed Yasser; Alalwani, Mohamad Sadek; Amer, Manal Fouad; Tarakji, Bassel; Aws, Ghassan

    2015-01-01

    Background: Infection prevention and control measures are critical to prevent the possible spread of Middle East Respiratory Syndrome-coronavirus (MERS-CoV) in healthcare facilities. Therefore, healthcare workers should be aware of all procedures concerning prevention of and protection from MERS-CoV. Objective: The aim of this study is to improve the knowledge of the dental students and evaluate their awareness about MERS-CoV. Materials and Methods: A questionnaire was made according to MOH information and 200 dental students (Al-Farabi Colleges, Jeddah) were interviewed to evaluate their knowledge about MERS-CoV. Results: More than half of the dental students (54%) interviewed had good knowledge about the etiology, symptoms, and treatment of MERS-CoV. Measurements for infection control and protection were also known (79%). The sources of information for the students were: college (27%), MOH (25%), media (24%), and social community (23%), while 17% of the students interviewed had no idea about it. Conclusion: Dental students had good knowledge about MERS-CoV. However, more information still must be provided by MOH and college for the medical staff. PMID:26236674

  17. Concentrating solar power in Europe, the Middle East and North Africa: achieving its potential

    NASA Astrophysics Data System (ADS)

    Pitz-Paal, R.; Amin, A.; Bettzüge, M.; Eames, P.; Fabrizi, F.; Flamant, G.; Garcia Novo, F.; Holmes, J.; Kribus, A.; van der Laan, H.; Lopez, C.; Papagiannakopoulos, P.; Pihl, E.; Smith, P.; Wagner, H.-J.

    2012-10-01

    Concentrating solar power (CSP) is a commercially available renewable energy technology capable of harnessing the immense solar resource in Southern Europe, the Middle East and North Africa (the MENA region), and elsewhere. This paper summarises the findings of a study by the European Academies Science Advisory Council which has examined the current status and development challenges of CSP, and consequently has evaluated the potential contribution of CSP in Europe and the MENA region to 2050. It identifies the actions that will be required by scientists, engineers, policy makers, politicians, business and investors alike, to enable this vast solar resource to make a major contribution to establishing a sustainable energy system. The study concludes that cost reductions of 50-60% in CSP electricity may reasonably be expected in the next 10-15 years, enabling the technology to be cost competitive with fossil-fired power generation at some point between 2020 and 2030. Incorporation of storage delivers added value in enabling CSP to deliver dispatchable power. Incentive schemes will be needed in Europe and MENA countries to enable this point to be achieved. Such schemes should reflect the true value of electricity to the grid, effectively drive R&D, and ensure transparency of performance and cost data.

  18. Male enhancement Nutraceuticals in the Middle East market: Claim, pharmaceutical quality and safety assessments.

    PubMed

    ElAgouri, Ghada; ElAmrawy, Fatema; ElYazbi, Ahmed; Eshra, Ahmed; Nounou, Mohamed I

    2015-08-15

    The global market is invaded by male enhancement nutraceuticals claimed to be of natural origin sold with a major therapeutic claim. Most of these products have been reported by international systems like the Food and Drug Administration (FDA). We hypothesize that these products could represent a major threat to the health of the consumers. In this paper, pharmaceutical evaluation of some of these nutraceutical products sold in Egypt under the therapeutic claim of treating erectile dysfunction, are discussed along with pharmacological evaluation to investigate their safety and efficacy parameters. Samples were analyzed utterly using conventional methods, i.e.: HPLC, HPTLC, NIR, content uniformity and weight variation and friability. The SeDeM system was used for quality assessment. On the basis of the results of this research, the sampled products are adulterated and totally heterogeneous in their adulterant drug content and pharmaceutical quality. These products represent a major safety threat for the consumers in Egypt and the Middle East, especially; the target audience is mostly affected with heart and blood pressure problems seeking natural and safe alternatives to the well-established Phosphodiesterase 5 Inhibitors (PDE-5Is).

  19. Geologic Map of the Middle East Rift Geothermal Subzone, Kilauea Volcano, Hawaii

    USGS Publications Warehouse

    Trusdell, Frank A.; Moore, Richard B.

    2006-01-01

    K'lauea is an active shield volcano in the southeastern part of the Island of Hawai'i. The middle east rift zone (MERZ) map includes about 27 square kilometers of the MERZ and shows the distribution of the products of 37 separate eruptions during late Holocene time. Lava flows erupted during 1983-96 have reached the mapped area. The subaerial part of the MERZ is 3-4 km wide and about 18 km long. It is a constructional ridge, 50-150 m above the adjoining terrain, marked by low spatter ramparts and cones as high as 60 m. Lava typically flowed either northeast or southeast, depending on vent location relative to the topographic crest of the rift zone. The MERZ receives more than 100 in. of rainfall annually and is covered by tropical rain forest. Vegetation begins to grow on lava a few months after its eruption. Relative heights of trees can be a guide to relative ages of underlying lava flows, but proximity to faults, presence of easily weathered cinders, and human activity also affect the rate of growth. The rocks have been grouped into five basic age groups. The framework for the ages assigned is provided by eight radiocarbon ages from previous mapping by the authors and a single date from the current mapping effort. The numerical ages are supplemented by observations of stratigraphic relations, degree of weathering, soil development, and vegetative cover.

  20. Prenatal metal exposure in the Middle East: imprint of war in deciduous teeth of children.

    PubMed

    Savabieasfahani, M; Ali, S Sadik; Bacho, R; Savabi, O; Alsabbak, M

    2016-09-01

    In war zones, the explosion of bombs, bullets, and other ammunition releases multiple neurotoxicants into the environment. The Middle East is currently the site of heavy environmental disruption by massive bombardments. A very large number of US military bases, which release highly toxic environmental contaminants, have also been erected since 2003. Current knowledge supports the hypothesis that war-created pollution is a major cause of rising birth defects and cancers in Iraq. We created elemental bio-imaging of trace elements in deciduous teeth of children with birth defects from Iraq. Healthy and naturally shed teeth from Lebanon and Iran were also analyzed for trace elements. Lead (Pb) was highest in teeth from children with birth defects who donated their teeth from Basra, Iraq (mean 0.73-16.74 (208)Pb/(43)Ca ppm, n = 3). Pb in healthy Lebanese and Iranian teeth were 0.038-0.382 (208)Pb/(43)Ca ppm (n = 4) and 0.041-0.31 (208)Pb/(43)Ca ppm (n = 2), respectively. Our hypothesis that increased war activity coincides with increased metal levels in deciduous teeth is confirmed by this research. Lead levels were similar in Lebanese and Iranian deciduous teeth. Deciduous teeth from Iraqi children with birth defects had remarkably higher levels of Pb. Two Iraqi teeth had four times more Pb, and one tooth had as much as 50 times more Pb than samples from Lebanon and Iran. PMID:27491948

  1. Characterization of a Novel Betacoronavirus Related to Middle East Respiratory Syndrome Coronavirus in European Hedgehogs

    PubMed Central

    Corman, Victor Max; Kallies, René; Philipps, Heike; Göpner, Gertraude; Müller, Marcel Alexander; Eckerle, Isabella; Brünink, Sebastian

    2014-01-01

    Bats are known to host viruses closely related to important human coronaviruses (HCoVs), such as HCoV-229E, severe-acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome CoV (MERS-CoV). As RNA viruses may coevolve with their hosts, we sought to investigate the closest sister taxon to bats, the Eulipotyphla, and screened European hedgehogs (Erinaceus europaeus) from Germany for CoV by nested reverse transcriptase PCR. A novel betacoronavirus species in a phylogenetic sister relationship to MERS-CoV and clade c bat CoVs was detected and characterized on the whole-genome level. A total of 58.9% of hedgehog fecal specimens were positive for the novel CoV (EriCoV) at 7.9 log10 mean RNA copies per ml. EriCoV RNA concentrations were higher in the intestine than in other solid organs, blood, or urine. Detailed analyses of the full hedgehog intestine showed the highest EriCoV concentrations in lower gastrointestinal tract specimens, compatible with viral replication in the lower intestine and fecal-oral transmission. Thirteen of 27 (48.2%) hedgehog sera contained non-neutralizing antibodies against MERS-CoV. The animal origins of this betacoronavirus clade that includes MERS-CoV may thus include both bat and nonbat hosts. PMID:24131722

  2. High correlation of Middle East respiratory syndrome spread with Google search and Twitter trends in Korea

    NASA Astrophysics Data System (ADS)

    Shin, Soo-Yong; Seo, Dong-Woo; An, Jisun; Kwak, Haewoon; Kim, Sung-Han; Gwack, Jin; Jo, Min-Woo

    2016-09-01

    The Middle East respiratory syndrome coronavirus (MERS-CoV) was exported to Korea in 2015, resulting in a threat to neighboring nations. We evaluated the possibility of using a digital surveillance system based on web searches and social media data to monitor this MERS outbreak. We collected the number of daily laboratory-confirmed MERS cases and quarantined cases from May 11, 2015 to June 26, 2015 using the Korean government MERS portal. The daily trends observed via Google search and Twitter during the same time period were also ascertained using Google Trends and Topsy. Correlations among the data were then examined using Spearman correlation analysis. We found high correlations (>0.7) between Google search and Twitter results and the number of confirmed MERS cases for the previous three days using only four simple keywords: “MERS”, “” (“MERS (in Korean)”), “” (“MERS symptoms (in Korean)”), and “” (“MERS hospital (in Korean)”). Additionally, we found high correlations between the Google search and Twitter results and the number of quarantined cases using the above keywords. This study demonstrates the possibility of using a digital surveillance system to monitor the outbreak of MERS.

  3. Metallogenic evolution of uranium deposits in the Middle East and North Africa deposits

    NASA Astrophysics Data System (ADS)

    Howari, Fares; Goodell, Philip; Salman, Abdulaty

    2016-02-01

    This paper is briefly involved in classification and distributions of the Middle East and North Africa (MENA) uranium deposits. The study of these mineral systems can significantly contribute to our further understanding of the metallogeny of known and poorly explored deposits. This provides contribution to, and further enhancement of, current classifications and metallogenic models of uranium systems, allowing researchers to emphasize on unknown or poorly studied mineral systems found in MENA. The present study identified eight metallogenic types of uranium associated with: 1) the Archean rocks and intra-cratonic basins, 2) the Pan-African granites and rhyolites which are characterized by igneous activity, 3) Phanerozoic (Paleozoic) clastics, these deposits are the sedimentological response to Pan African magmatism, 4) Mesozoic (basal) clastics type e.g. Nubia sandstones which are characterized by uranium minerals, 5) regional sedimentary phosphate deposits which are categorized as geosynclinal, or continental margin deposits, on the shelf of the Tethys Ocean, 6) Cenozoic Intracratonic Felsic Magmatism of the Tibesti and Hoggar, and the sandstone U deposits of adjoining Niger. These are similar to the Pan-African magmatism metallogenic, 7) Calcretes, and 8) Resistate minerals which are often enriched in rare earth elements, sometimes including uranium. They are thus sometimes considered as U resources but poorly explored in the MENA region. These metallogenic types are described and discussed in the current paper.

  4. Abortion and Islam: policies and practice in the Middle East and North Africa.

    PubMed

    Hessini, Leila

    2007-05-01

    This paper provides an overview of legal, religious, medical and social factors that serve to support or hinder women's access to safe abortion services in the 21 predominantly Muslim countries of the Middle East and North Africa (MENA) region, where one in ten pregnancies ends in abortion. Reform efforts, including progressive interpretations of Islam, have resulted in laws allowing for early abortion on request in two countries; six others permit abortion on health grounds and three more also allow abortion in cases of rape or fetal impairment. However, medical and social factors limit access to safe abortion services in all but Turkey and Tunisia. To address this situation, efforts are increasing in a few countries to introduce post-abortion care, document the magnitude of unsafe abortion and understand women's experience of unplanned pregnancy. Religious fatāwa have been issued allowing abortions in certain circumstances. An understanding of variations in Muslim beliefs and practices, and the interplay between politics, religion, history and reproductive rights is key to understanding abortion in different Muslim societies. More needs to be done to build on efforts to increase women's rights, engage community leaders, support progressive religious leaders and government officials and promote advocacy among health professionals. PMID:17512379

  5. Keratitis–ichthyosis–deafness syndrome: first affected family reported in the Middle East

    PubMed Central

    Al Fahaad, Hamad

    2014-01-01

    Introduction Keratitis–ichthyosis–deafness (KID) syndrome is a rare congenital multisystem disorder affecting certain tissues of ectodermal origin such as epidermis, cochlea, and cornea, leading mainly to palmoplantar hyperkeratosis, ichthyosiform scaling, deafness, and blindness. The author reports for the first time in the Middle East three family members suffering from KID syndrome in the southwestern part of Saudi Arabia. Case presentation Three patients from one family (ages 26, 16, and 14 years) of apparently normal parents, with the two eldest being females and the youngest being male. All three patients were referred from a peripheral hospital to our dermatology clinic due to recurrent cutaneous fungal infections on their trunk, forearms, legs, and nails. On full assessment, they also found to have nearly similar cutaneous problems manifested by palmoplantar hyperkeratosis, generalized ichthyosiform scaling, subungual hyperkeratosis, and nail dystrophies. All patients suffered from total hearing loss in both ears since childhood as confirmed by pure tune audiometry. However, there was no blindness in any case; blepharitis with marked photophobia was the only ocular complaint. All these features are classically suggestive of KID syndrome. PMID:24741331

  6. Diagenetic evolution and petrophysical characteristics of oomoldic facies in United States and Middle East reservoirs

    SciTech Connect

    Nurmi, R.; Neuberger, D.

    1987-08-01

    The diagenetic evolution of oomoldic pore rocks from US and Middle East reservoirs were studied to determine their variation. The oomolds in all of the reservoir samples appear to have formed prior to any compaction, and were also subject to early cementation, which preserved the delicate structure of these rocks. The most common oomold-filling mineral is calcite, regardless of whether the remainder of the rock is dolostone or limestone. Anhydrite is commonly the mineral filling oomolds in formations depositionally associated with evaporites. Partial cementation of individual oomolds is rare. However, partial filling of oomoldic wackestones by lime mud was observed. The petrophysical characteristics of oomoldic rocks in different stages of diagenetic evolution were analyzed using thin sections, pore casts, porosity and permeability measurements, and saturation. The rocks used in the study included core samples from the Lansing-Kansas City Group, San Andres, Smackover, Arab, and Khuff formations. Selected samples from the Lansing-Kansas City Groups were also measured for formation factor, density, and for dielectric and acoustic properties. The study quantified the relationship of pore type and volume with both formation factor and permeability of oomoldic rocks. The framework mineralogy (calcite or dolomite) and microstructure, and the presence and nature of interparticle pore-filling cements are critical factors in assessing the reservoir potential of an oomoldic reservoir facies. Furthermore, the geologic analysis of the pore system can greatly improve the determination of the Archie m exponent, which provides more reasonable evaluations of the saturation and permeability of these complex rocks.

  7. SESAME-A 3rd Generation Synchrotron Light Source for the Middle East

    NASA Astrophysics Data System (ADS)

    Winick, Herman

    2010-02-01

    Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research center in construction in Jordan. It will enable world class research by scientists from the region, reversing the brain drain. It will also build bridges between diverse societies, contributing to a culture of peace through international cooperation in science. The centerpiece is a synchrotron light source originating from BESSY I, a gift by Germany. The upgraded machine, a 2.5 GeV 3rd Generation Light Source (133m circumference, 26nm-rad emittance and 12 places for insertion devices), will provide light from infra-red to hard X-rays, offering excellent opportunities to train local scientists and attract those working abroad to return. The SESAME Council meets twice each year and presently has nine Members (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority, Turkey). Members have responsibility for the project and provide the annual operations budget (1.5M US dollars in 2009, expected to rise to about 5M when operation starts in 2012-13). Jordan provided the site, building, and infrastructure. A staff of 20 is installing the 0.8 GeV BESSY I injection system. The facility will have the capacity to serve 30 or more experiments operating simultaneously. See www.sesame.org.jo )

  8. The emergence of the Middle East Respiratory Syndrome coronavirus (MERS-CoV)

    PubMed Central

    Milne-Price, Shauna; Miazgowicz, Kerri L.; Munster, Vincent J.

    2014-01-01

    On September 20, 2012, a Saudi Arabian physician reported the isolation of a novel coronavirus from a patient with pneumonia on ProMED-mail. Within a few days the same virus was detected in a Qatari patient receiving intensive care in a London hospital, a situation reminiscent of the role air travel played in the spread of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) in 2002. SARS-CoV originated in China’s Guangdong Province and affected more than 8000 patients in 26 countries before it was contained six months later. Over a year after the emergence of this novel coronavirus—Middle East Respiratory Syndrome coronavirus (MERS-CoV)—it has caused 178 laboratory confirmed cases and 76 deaths The emergence of a second highly pathogenic coronavirus within a decade highlights the importance of a coordinated global response incorporating reservoir surveillance, high-containment capacity with fundamental and applied research programs, and dependable communication pathways to ensure outbreak containment. Here we review the current state of knowledge on the epidemiology, ecology, molecular biology, clinical features and intervention strategies of the novel coronavirus, MERS-CoV. PMID:24585737

  9. Medication risk communication with cancer patients in a Middle East cancer care setting

    PubMed Central

    Wilbur, Kerry; Al-Okka, Maha; Jumaat, Ebaa; Eissa, Nesma; Elbashir, Merwa; Al-Yafei, Sumaya M Al Saadi

    2016-01-01

    Purpose Cancer treatments are frequently associated with adverse effects, but there may be a cultural reluctance by care providers to be forthcoming with patients regarding these risks for fear of promoting nonadherence. Conversely, research in a number of countries indicates high levels of patient desire for this information. We sought to explore cancer patient experiences, satisfaction, and preferences for medication risk communication in a Middle East care setting. Methods We developed and administered a ten-item questionnaire (Arabic and English) to a convenience sample of consenting adult patients receiving treatment at the National Center for Cancer Care and Research in Qatar. Results One hundred and forty-three patients were interviewed. Most (88%) stated that the level of side effect information they received was sufficient, with physicians (86%) followed by pharmacists (39%) as the preferred sources. The majority (97%) agreed that knowing about possible side effects would help them recognize and manage the reaction, and 92% agreed that it would help them understand how to minimize or prevent the risks. Eighteen percent indicated that this information would make them not want to take treatment. Two-thirds (65%) had previously experienced intolerance to their cancer treatment regimen. Conclusion Most patients surveyed expressed preference for the details of possible side effects they may encounter in their treatment. However, one in five considered such information a factor for nonadherence, indicating the need for patient-specific approaches when communicating medication risks. PMID:27175061

  10. Preliminary definition of geophysical regions for the Middle East and North Africa

    SciTech Connect

    Sweeney, J J; Walter, B

    1998-12-01

    The ability to calibrate seismic stations to improve the monitoring of the Comprehensive Test Ban Treaty is partially limited by the availability of seismic events with known locations and source properties. To confidently extrapolate from these events to aseismic regions, and to properly account for discontinuities in seismic properties requires accurate geophysical models. This paper lays out a preliminary, first-order, regionalization of the Middle East and North African (MENA) region. The model specifies boundaries and velocity structures based on the geology and tectonics of the region, previously published studies, and empirical data observations by the LLNL group. This model is a starting point and is expected to be improved and refined by comparisons with ongoing tomography efforts and the collection of new data. We anticipate that this model and its successors will prove useful as a background model in the process of forming station calibration maps based on intelligent interpolation techniques such as kriging. We also hope the model, as it improves and demonstrates some predictive power, will provide a reference model for broader CTBT research efforts in detection, location and discrimination as well as other aspects of earth science.

  11. Increased seasonality in Middle East temperatures during the last interglacial period.

    PubMed

    Felis, Thomas; Lohmann, Gerrit; Kuhnert, Henning; Lorenz, Stephan J; Scholz, Denis; Pätzold, Jürgen; Al-Rousan, Saber A; Al-Moghrabi, Salim M

    2004-05-13

    The last interglacial period (about 125,000 years ago) is thought to have been at least as warm as the present climate. Owing to changes in the Earth's orbit around the Sun, it is thought that insolation in the Northern Hemisphere varied more strongly than today on seasonal timescales, which would have led to corresponding changes in the seasonal temperature cycle. Here we present seasonally resolved proxy records using corals from the northernmost Red Sea, which record climate during the last interglacial period, the late Holocene epoch and the present. We find an increased seasonality in the temperature recorded in the last interglacial coral. Today, climate in the northern Red Sea is sensitive to the North Atlantic Oscillation, a climate oscillation that strongly influences winter temperatures and precipitation in the North Atlantic region. From our coral records and simulations with a coupled atmosphere-ocean circulation model, we conclude that a tendency towards the high-index state of the North Atlantic Oscillation during the last interglacial period, which is consistent with European proxy records, contributed to the larger amplitude of the seasonal cycle in the Middle East. PMID:15141207

  12. Diabetes in the Middle-East and North Africa: an update.

    PubMed

    Majeed, Azeem; El-Sayed, Adel A; Khoja, Tawfik; Alshamsan, Riyadh; Millett, Christopher; Rawaf, Salman

    2014-02-01

    In recent decades, the prevalence of diabetes has risen dramatically in many countries of the International Diabetes Federation's (IDF) Middle-East and North Africa (MENA) Region. This increase has been driven by a range of factors that include rapid economic development and urbanisation; changes in lifestyle that have led to reduced levels of physical activity, increased intake of refined carbohydrates, and a rise in obesity. These changes have resulted in the countries of MENA Region now having among the highest rates of diabetes prevalence in the world. The current prevalence of diabetes in adults in the Region is estimated to be around 9.2%. Of the 34 million people affected by diabetes, nearly 17 million were undiagnosed and therefore at considerable risk of diabetes complications and poor health outcomes. Enhanced research on the epidemiology of diabetes in the MENA Region needs to be combined with more effective primary prevention of diabetes; and early detection and improved management of patients with established diabetes, including an increased focus on self-management and management in primary care and community settings. PMID:24300017

  13. Medical educators working abroad: a pilot study of educators' experiences in the Middle East.

    PubMed

    McLean, Michelle; McKimm, Judy; Major, Stella

    2014-09-01

    Medical education is now a global enterprise, with many medical educators working internationally, either for short or longer periods or even permanently. In parallel, many medical schools are now involved in collaborations and partnerships with schools in other countries. With this in mind, we set out to explore what motivates, supports and inhibits medical educators who wish to or might work outside their "home country". This article reports on the pilot stage (in specific organizational contexts in Middle East) of a longitudinal project aimed at canvassing medical educators on a broader global scale, using reflective accounts and a questionnaire survey. The findings from this pilot study raise interesting issues about the lived experience of medical educators who have chosen to work in a different culture from their own. Respondents identify many advantages around skills, personal and professional development. Three main issues emerged in terms of educators' experiences: the academic environment, medical practice in a different cultural context and personal matters. Adapting to the local culture, gender segregation and the impact on learning and teaching was an overarching factor. We introduce an explanatory framework to explain the development of international educator identity, a cyclical process in which, through experiences and reflection, individual world views and perspectives are continually modified and developed. This pilot study tested the methodologies and developed a new conceptual model that will be used in a wider study across different cultures.

  14. A lesson learned from Middle East respiratory syndrome (MERS) in Saudi Arabia.

    PubMed

    Al Shehri, Ali M

    2015-04-01

    Middle East respiratory syndrome (MERS) caused by novel Corona virus hit Kingdom of Saudi Arabia (KSA) and resulted in hundreds of mortality and morbidity, fears and psychosocial stress among population, economic loss and major political change at Ministry of Health (MoH). Although MERS discovered two years ago, confusion still exists about its origin, nature, and consequences. In 2003, similar virus (SARS) hit Canada and resulted in a reform of Canada's public health system and creation of a Canadian Agency for Public Health, similar to the US Centers for Disease Control (CDC). The idea of Saudi CDC is attractive and even "sexy" but it is not the best option. Experience and literature indicate that the best option for KSA is to revitalize national public health systems on the basis of comprehensive, continuing, and integrated primary health care (PHC) and public health (PH). This article proposes three initial, but essential, steps for such revitalization to take place: political will and support, integration of PHC and PH, and on-job professional programs for the workforce. In addition, current academic and training programs for PHC and PH should be revisited in the light of national vision and strategy that aim for high quality products that protect and promote healthy nation. Scientific associations, medical education research chair, and relevant academic bodies should be involved in the revitalization to ensure quality of process and outcomes. PMID:25803593

  15. Diversity of Cronobacter spp. isolates from the vegetables in the middle-east coastline of China.

    PubMed

    Chen, Wanyi; Yang, Jielin; You, Chunping; Liu, Zhenmin

    2016-06-01

    Cronobacter spp. has caused life-threatening neonatal infections mainly resulted from consumption of contaminated powdered infant formula. A total of 102 vegetable samples from retail markets were evaluated for the presence of Cronobacter spp. Thirty-five presumptive Cronobacter isolates were isolated and identified using API 20E and 16S rDNA sequencing analyses. All isolates and type strains were characterized using enterobacterial repetitive intergenic consensus sequence PCR (ERIC-PCR), and genetic profiles of cluster analysis from this molecular typing test clearly showed that there were differences among isolates from different vegetables. A polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) based on the amplification of the gyrB gene (1258 bp) was developed to differentiate among Cronobacter species. A new PCR-RFLP assay based on the amplification of the gyrB gene using Alu I and Hinf I endonuclease combination is established and it has been confirmed an accurate and rapid subtyping method to differentiate Cronobacter species. Sequence analysis of the gyrB gene was proven to be suitable for the phylogenetic analysis of the Cronobacter strains, which has much better resolution based on SNPs in the identification of Cronobacter species specificity than PCR-RFLP and ERIC-PCR. Our study further confirmed that vegetables are one of the most common habitats or sources of Cronobacter spp. contamination in the middle-east coastline of China. PMID:27116956

  16. Middle East Respiratory Syndrome Coronavirus Transmission in Extended Family, Saudi Arabia, 2014

    PubMed Central

    Arwady, M. Allison; Alraddadi, Basem; Basler, Colin; Azhar, Esam I.; Abuelzein, Eltayb; Sindy, Abdulfattah I.; Sadiq, Bakr M. Bin; Althaqafi, Abdulhakeem O.; Shabouni, Omaima; Banjar, Ayman; Haynes, Lia M.; Gerber, Susan I.; Feikin, Daniel R.

    2016-01-01

    Risk factors for human-to-human transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) are largely unknown. After MERS-CoV infections occurred in an extended family in Saudi Arabia in 2014, relatives were tested by using real-time reverse transcription PCR (rRT-PCR) and serologic methods. Among 79 relatives, 19 (24%) were MERS-CoV positive; 11 were hospitalized, and 2 died. Eleven (58%) tested positive by rRT-PCR; 8 (42%) tested negative by rRT-PCR but positive by serology. Compared with MERS-CoV–negative adult relatives, MERS-CoV–positive adult relatives were older and more likely to be male and to have chronic medical conditions. Risk factors for household transmission included sleeping in an index patient’s room and touching respiratory secretions from an index patient. Casual contact and simple proximity were not associated with transmission. Serology was more sensitive than standard rRT-PCR for identifying infected relatives, highlighting the value of including serology in future investigations. PMID:27191038

  17. The Qatar genome: a population-specific tool for precision medicine in the Middle East

    PubMed Central

    Fakhro, Khalid A; Staudt, Michelle R; Ramstetter, Monica Denise; Robay, Amal; Malek, Joel A; Badii, Ramin; Al-Marri, Ajayeb Al-Nabet; Khalil, Charbel Abi; Al-Shakaki, Alya; Chidiac, Omar; Stadler, Dora; Zirie, Mahmoud; Jayyousi, Amin; Salit, Jacqueline; Mezey, Jason G; Crystal, Ronald G; Rodriguez-Flores, Juan L

    2016-01-01

    Reaching the full potential of precision medicine depends on the quality of personalized genome interpretation. In order to facilitate precision medicine in regions of the Middle East and North Africa (MENA), a population-specific genome for the indigenous Arab population of Qatar (QTRG) was constructed by incorporating allele frequency data from sequencing of 1,161 Qataris, representing 0.4% of the population. A total of 20.9 million single nucleotide polymorphisms (SNPs) and 3.1 million indels were observed in Qatar, including an average of 1.79% novel variants per individual genome. Replacement of the GRCh37 standard reference with QTRG in a best practices genome analysis workflow resulted in an average of 7* deeper coverage depth (an improvement of 23%) and 756,671 fewer variants on average, a reduction of 16% that is attributed to common Qatari alleles being present in QTRG. The benefit for using QTRG varies across ancestries, a factor that should be taken into consideration when selecting an appropriate reference for analysis. PMID:27408750

  18. Mobilizing the Global Scientific Enterprise to Foster Cooperation with the Middle East

    NASA Astrophysics Data System (ADS)

    Turekian, Vaughan

    2007-03-01

    International science cooperation - e.g. science for diplomacy - has long been an important tool in the US foreign policy approach. Cold War science exchanges and development of institutions such as IIASA in Vienna, Austria played a critical role in increasing contacts and building trust between the adversaries. American - Chinese science exchanges starting in the 1970's laid the groundwork for increased interactions between the two countries. While such a deep history of exchange with the Muslim world U.S. policy, scientific diplomacy should now be a central point of any broader diplomatic engagement with these countries. Although perceptions of the U.S. are at historical lows throughout the region, recent polling continues to show that U.S. science and scientists remain highly respected. In part as a response to this unpopularity of the U.S. throughout the broader Middle East, President Bush appointed Karen Hughes, one of his most trusted advisers, to serve as the Under Secretary of State for Public Diplomacy - a position that is charges with improving the U.S. image abroad. This presentation will demonstrate that Under Secretary Hughes has valuable resources within the scientific community that are willing, able and proactively engaging with the Muslim world. The paper will highlight some of the key areas of cooperation, and highlight areas and programs that AAAS is using to further engage elements of the Muslim scientific community.

  19. SSA 02-2 CHANGING CONCEPTS IN THE MANAGEMENT OF HYPERTENSION: MIDDLE EAST.

    PubMed

    Berbari, Adel

    2016-09-01

    The Middle East Region is undergoing a transition from communicable to non-communicable disease. Although the population is to a large extent young, there is also an increasing number of elderly people due to improved health care facilities and socioeconomic status. Similar to developing countries, there is a high burden of cardiovascular risk factors.Hypertension, a major cause of increased morbidity and mortality from cardiovascular events, is quite prevalent, varying from 25-40%, associated with an increased prevalence of obesity, diabetes mellitus and high salt intake.With improvement of socioeconomic conditions and increased rate of education, there is a changing concept in the evaluation and management of hypertension, due largely to an increased number of local hypertension societies which follow guidelines recommended by international hypertension societies. Blood pressure measurement is still determined by mercury sphygmomanometers although automatic oscillometric manometers are increasingly used. Further, ambulatory blood pressure measurement is also recommended by a large number of healthcare professionals.Lifestyle measures are increasingly recommended including weight reduction, salt restriction, nicotine/smoking cessation and increased physical activity.Blood pressure goals for control of hypertension depend upon the countries. Combination pharmacotherapy is often initiated with combination therapy. Diuretics remain however the major antihypertensive agent used in most countries. PMID:27642930

  20. Strong Lg-wave attenuation in the Middle East continental collision orogenic belt

    NASA Astrophysics Data System (ADS)

    Zhao, Lian-Feng; Xie, Xiao-Bi

    2016-04-01

    Using Lg-wave Q tomography, we construct a broadband crustal attenuation model for the Middle East. The QLg images reveal a relationship between attenuation and geological structures. Strong attenuation is found in the continental collision orogenic belt that extends from the Turkish and Iranian plateau to the Pamir plateau. We investigate the frequency dependence of QLg in different geologic formations. The results illustrate that QLg values generally increase with increasing frequency but exhibit complex relationships both with frequency and between regions. An average QLg value between 0.2 and 2.0 Hz, QLg (0.2-2.0 Hz), may be a critical index for crustal attenuation and is used to infer the regional geology. Low-QLg anomalies are present in the eastern Turkish plateau and correlate well with low Pn-velocities and Cenozoic volcanic activity, thus indicating possible partial melting within the crust in this region. Very strong attenuation is also observed in central Iran, the Afghanistan block, and the southern Caspian Sea. This in line with the previously observed high crustal temperature, high-conductivity layers, and thick marine sediments in these areas, suggests the high Lg attenuation is caused by abnormally high tectonic and thermal activities.

  1. Ethical Perspectives on the Middle East Respiratory Syndrome Coronavirus Epidemic in Korea.

    PubMed

    Kim, Ock-Joo

    2016-01-01

    Ethical considerations are essential in planning for and responding to outbreaks of infectious diseases. During the outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in the Republic of Korea in 2015, serious challenges emerged regarding important ethical issues, such as transparency and the protection of privacy. The development of bioethics in Korea has been influenced by individualistic perspectives applied in clinical contexts, leading to a paucity of ethical perspectives relevant to population-level phenomena such as outbreaks. Alternative theories of public health ethics include the perspectives of relational autonomy and the patient as victim and vector. Public health actions need to incorporate clear and systematic procedures founded upon ethical principles. The MERS-CoV epidemic in Korea created significant public support for more aggressive early interventions in future outbreaks. This trend makes it all the more imperative for ethical principles and procedures to be implemented in future planning and responses to outbreaks in order to promote perceptions of legitimacy and civic participation.

  2. High correlation of Middle East respiratory syndrome spread with Google search and Twitter trends in Korea.

    PubMed

    Shin, Soo-Yong; Seo, Dong-Woo; An, Jisun; Kwak, Haewoon; Kim, Sung-Han; Gwack, Jin; Jo, Min-Woo

    2016-01-01

    The Middle East respiratory syndrome coronavirus (MERS-CoV) was exported to Korea in 2015, resulting in a threat to neighboring nations. We evaluated the possibility of using a digital surveillance system based on web searches and social media data to monitor this MERS outbreak. We collected the number of daily laboratory-confirmed MERS cases and quarantined cases from May 11, 2015 to June 26, 2015 using the Korean government MERS portal. The daily trends observed via Google search and Twitter during the same time period were also ascertained using Google Trends and Topsy. Correlations among the data were then examined using Spearman correlation analysis. We found high correlations (>0.7) between Google search and Twitter results and the number of confirmed MERS cases for the previous three days using only four simple keywords: "MERS", " ("MERS (in Korean)"), " ("MERS symptoms (in Korean)"), and " ("MERS hospital (in Korean)"). Additionally, we found high correlations between the Google search and Twitter results and the number of quarantined cases using the above keywords. This study demonstrates the possibility of using a digital surveillance system to monitor the outbreak of MERS. PMID:27595921

  3. Standard and AEGIS nicking molecular beacons detect amplicons from the Middle East respiratory syndrome coronavirus.

    PubMed

    Yaren, Ozlem; Glushakova, Lyudmyla G; Bradley, Kevin M; Hoshika, Shuichi; Benner, Steven A

    2016-10-01

    This paper combines two advances to detect MERS-CoV, the causative agent of Middle East Respiratory Syndrome, that have emerged over the past few years from the new field of "synthetic biology". Both are based on an older concept, where molecular beacons are used as the downstream detection of viral RNA in biological mixtures followed by reverse transcription PCR amplification. The first advance exploits the artificially expanded genetic information systems (AEGIS). AEGIS adds nucleotides to the four found in standard DNA and RNA (xNA); AEGIS nucleotides pair orthogonally to the A:T and G:C pairs. Placing AEGIS components in the stems of molecular beacons is shown to lower noise by preventing unwanted stem invasion by adventitious natural xNA. This should improve the signal-to-noise ratio of molecular beacons operating in complex biological mixtures. The second advance introduces a nicking enzyme that allows a single target molecule to activate more than one beacon, allowing "signal amplification". Combining these technologies in primers with components of a self-avoiding molecular recognition system (SAMRS), we detect 50 copies of MERS-CoV RNA in a multiplexed respiratory virus panel by generating fluorescence signal visible to human eye and/or camera.

  4. Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein.

    PubMed

    Xia, Shuai; Liu, Qi; Wang, Qian; Sun, Zhiwu; Su, Shan; Du, Lanying; Ying, Tianlei; Lu, Lu; Jiang, Shibo

    2014-12-19

    The recent outbreak of Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) infection has led to more than 800 laboratory-confirmed MERS cases with a high case fatality rate (∼35%), posing a serious threat to global public health and calling for the development of effective and safe therapeutic and prophylactic strategies to treat and prevent MERS-CoV infection. Here we discuss the most recent studies on the structure of the MERS-CoV spike protein and its role in virus binding and entry, and the development of MERS-CoV entry/fusion inhibitors targeting the S1 subunit, particularly the receptor-binding domain (RBD), and the S2 subunit, especially the HR1 region, of the MERS-CoV spike protein. We then look ahead to future applications of these viral entry/fusion inhibitors, either alone or in combination with specific and nonspecific MERS-CoV replication inhibitors, for the treatment and prevention of MERS-CoV infection. PMID:25451066

  5. SESAME -- A third generation synchrotron light source for the Middle East

    NASA Astrophysics Data System (ADS)

    Winick, Herman

    2012-03-01

    Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research centre in construction in Jordan, enabling world-class research while promoting peace through scientific cooperation. Its centerpiece, a new 2.5 GeV 3rd Generation Electron Storage Ring (133m circumference, 26nm-rad emittance, 12 places for insertion devices), will provide intense light from infra-red to hard X-rays. Members of the Council (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority,Turkey) provide the operations budget. Voluntary contributions by several Council Members that could amount to over 20 million over 5 years are now being finalized. This, plus funds from other sources, will enable acquisition of the technical components of the new ring and the upgrading of beamline equipment donated by several European and US labs. All concrete shielding is complete. The 0.8 GeV BESSY I injector system, a gift from Germany, is now being installed. A training program has been underway since 2000. SESAME is on track to start operation with four day-one beam lines in 2015.

  6. Reverse transcription recombinase polymerase amplification assay for the detection of middle East respiratory syndrome coronavirus.

    PubMed

    Abd El Wahed, Ahmed; Patel, Pranav; Heidenreich, Doris; Hufert, Frank T; Weidmann, Manfred

    2013-12-12

    The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the eastern Mediterranean and imported cases to Europe has alerted public health authorities. Currently, detection of MERS-CoV in patient samples is done by real-time RT-PCR. Samples collected from suspected cases are sent to highly-equipped centralized laboratories for screening. A rapid point-of-care test is needed to allow more widespread mobile detection of the virus directly from patient material. In this study, we describe the development of a reverse transcription isothermal Recombinase Polymerase Amplification (RT-RPA) assay for the identification of MERS-CoV. A partial nucleocapsid gene RNA molecular standard of MERS-coronavirus was used to determine the assay sensitivity. The isothermal (42°C) MERS-CoV RT-RPA was as sensitive as real-time RT-PCR (10 RNA molecules), rapid (3-7 minutes) and mobile (using tubescanner weighing 1kg). The MERS-CoV RT-RPA showed cross-detection neither of any of the RNAs of several coronaviruses and respiratory viruses affecting humans nor of the human genome. The developed isothermal real-time RT-RPA is ideal for rapid mobile molecular MERS-CoV monitoring in acute patients and may also facilitate the search for the animal reservoir of MERS-CoV.

  7. Ethical Perspectives on the Middle East Respiratory Syndrome Coronavirus Epidemic in Korea

    PubMed Central

    2016-01-01

    Ethical considerations are essential in planning for and responding to outbreaks of infectious diseases. During the outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in the Republic of Korea in 2015, serious challenges emerged regarding important ethical issues, such as transparency and the protection of privacy. The development of bioethics in Korea has been influenced by individualistic perspectives applied in clinical contexts, leading to a paucity of ethical perspectives relevant to population-level phenomena such as outbreaks. Alternative theories of public health ethics include the perspectives of relational autonomy and the patient as victim and vector. Public health actions need to incorporate clear and systematic procedures founded upon ethical principles. The MERS-CoV epidemic in Korea created significant public support for more aggressive early interventions in future outbreaks. This trend makes it all the more imperative for ethical principles and procedures to be implemented in future planning and responses to outbreaks in order to promote perceptions of legitimacy and civic participation. PMID:26841881

  8. High correlation of Middle East respiratory syndrome spread with Google search and Twitter trends in Korea

    PubMed Central

    Shin, Soo-Yong; Seo, Dong-Woo; An, Jisun; Kwak, Haewoon; Kim, Sung-Han; Gwack, Jin; Jo, Min-Woo

    2016-01-01

    The Middle East respiratory syndrome coronavirus (MERS-CoV) was exported to Korea in 2015, resulting in a threat to neighboring nations. We evaluated the possibility of using a digital surveillance system based on web searches and social media data to monitor this MERS outbreak. We collected the number of daily laboratory-confirmed MERS cases and quarantined cases from May 11, 2015 to June 26, 2015 using the Korean government MERS portal. The daily trends observed via Google search and Twitter during the same time period were also ascertained using Google Trends and Topsy. Correlations among the data were then examined using Spearman correlation analysis. We found high correlations (>0.7) between Google search and Twitter results and the number of confirmed MERS cases for the previous three days using only four simple keywords: “MERS”, “” (“MERS (in Korean)”), “” (“MERS symptoms (in Korean)”), and “” (“MERS hospital (in Korean)”). Additionally, we found high correlations between the Google search and Twitter results and the number of quarantined cases using the above keywords. This study demonstrates the possibility of using a digital surveillance system to monitor the outbreak of MERS. PMID:27595921

  9. Prenatal metal exposure in the Middle East: imprint of war in deciduous teeth of children.

    PubMed

    Savabieasfahani, M; Ali, S Sadik; Bacho, R; Savabi, O; Alsabbak, M

    2016-09-01

    In war zones, the explosion of bombs, bullets, and other ammunition releases multiple neurotoxicants into the environment. The Middle East is currently the site of heavy environmental disruption by massive bombardments. A very large number of US military bases, which release highly toxic environmental contaminants, have also been erected since 2003. Current knowledge supports the hypothesis that war-created pollution is a major cause of rising birth defects and cancers in Iraq. We created elemental bio-imaging of trace elements in deciduous teeth of children with birth defects from Iraq. Healthy and naturally shed teeth from Lebanon and Iran were also analyzed for trace elements. Lead (Pb) was highest in teeth from children with birth defects who donated their teeth from Basra, Iraq (mean 0.73-16.74 (208)Pb/(43)Ca ppm, n = 3). Pb in healthy Lebanese and Iranian teeth were 0.038-0.382 (208)Pb/(43)Ca ppm (n = 4) and 0.041-0.31 (208)Pb/(43)Ca ppm (n = 2), respectively. Our hypothesis that increased war activity coincides with increased metal levels in deciduous teeth is confirmed by this research. Lead levels were similar in Lebanese and Iranian deciduous teeth. Deciduous teeth from Iraqi children with birth defects had remarkably higher levels of Pb. Two Iraqi teeth had four times more Pb, and one tooth had as much as 50 times more Pb than samples from Lebanon and Iran.

  10. Geology and Nonfuel Mineral Deposits of Africa and the Middle East

    USGS Publications Warehouse

    Taylor, Cliff D.; Schulz, Klaus J.; Doebrich, Jeff L.; Orris, Greta; Denning, Paul D.; Kirschbaum, Michael J.

    2009-01-01

    A nation's endowment of nonfuel mineral resources, relative to the world's endowment, is a fundamental consideration in decisions related to a nation's economic and environmental well being and security. Knowledge of the worldwide abundance, distribution, and general geologic setting of mineral commodities provides a framework within which a nation can make decisions about economic development of its own resources, and the economic and environmental consequences of those decisions, in a global perspective. The information in this report is part of a U.S. Geological Survey (USGS) endeavor to evaluate the global endowment of both identified and undiscovered nonfuel mineral resources. The results will delineate areas of the world that are geologically permissive for the occurrence of undiscovered selected nonfuel mineral resources together with estimates of the quantity and quality of the resources. The results will be published as a series of regional reports; this one provides basic data on the identified resources and geologic setting, together with a brief appraisal of the potential for undiscovered mineral resources in Africa and the Middle East. Additional information, such as production statistics, economic factors that affect the mineral industries of the region, and historical information, is available in U.S. Geological Survey publications such as the Minerals Yearbook and the annual Mineral Commodity Summaries (available at http://minerals.usgs.gov/minerals).

  11. The role of Congress in arms transfer to the Middle East, 1976-1988

    SciTech Connect

    Ghanem, M.E.

    1991-01-01

    This study examines how domestic considerations affect the conduct of foreign policy of the Unites States. Taking the role of Congress in arms transfer to the Middle East as a case in point, the study identifies the major actors in the arms transfer policymaking process, examines the dynamic and fluid relationship between those actors, explores how Congress voted on arms transfer to moderate Arab countries, and also addresses the question of why members of Congress voted the way they did on this issue. Arms transfer involves companies that make the arms to be transferred and ethnic groups who have emotional ties to their countries of origin requesting the arms. Except for the Arms Export Control Act of 1976, Congress has not been an initiator in arms-transfer policymaking; its role has been confined to fine-tuning arms transfers rather than blocking, vetoing them. The executive branch is still in control of arms-transfer policymaking. The House and Senate have behaved differently on exporting arms to Arab countries. The House has been more opposed to such arms sales than the Senate.

  12. Repurposing of clinically developed drugs for treatment of Middle East respiratory syndrome coronavirus infection.

    PubMed

    Dyall, Julie; Coleman, Christopher M; Hart, Brit J; Venkataraman, Thiagarajan; Holbrook, Michael R; Kindrachuk, Jason; Johnson, Reed F; Olinger, Gene G; Jahrling, Peter B; Laidlaw, Monique; Johansen, Lisa M; Lear-Rooney, Calli M; Glass, Pamela J; Hensley, Lisa E; Frieman, Matthew B

    2014-08-01

    Outbreaks of emerging infections present health professionals with the unique challenge of trying to select appropriate pharmacologic treatments in the clinic with little time available for drug testing and development. Typically, clinicians are left with general supportive care and often untested convalescent-phase plasma as available treatment options. Repurposing of approved pharmaceutical drugs for new indications presents an attractive alternative to clinicians, researchers, public health agencies, drug developers, and funding agencies. Given the development times and manufacturing requirements for new products, repurposing of existing drugs is likely the only solution for outbreaks due to emerging viruses. In the studies described here, a library of 290 compounds was screened for antiviral activity against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus (SARS-CoV). Selection of compounds for inclusion in the library was dependent on current or previous FDA approval or advanced clinical development. Some drugs that had a well-defined cellular pathway as target were included. In total, 27 compounds with activity against both MERS-CoV and SARS-CoV were identified. The compounds belong to 13 different classes of pharmaceuticals, including inhibitors of estrogen receptors used for cancer treatment and inhibitors of dopamine receptor used as antipsychotics. The drugs identified in these screens provide new targets for in vivo studies as well as incorporation into ongoing clinical studies. PMID:24841273

  13. Reverse Transcription Recombinase Polymerase Amplification Assay for the Detection of Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Abd El Wahed, Ahmed; Patel, Pranav; Heidenreich, Doris; Hufert, Frank T.; Weidmann, Manfred

    2013-01-01

    The emergence of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in the eastern Mediterranean and imported cases to Europe has alerted public health authorities. Currently, detection of MERS-CoV in patient samples is done by real-time RT-PCR. Samples collected from suspected cases are sent to highly-equipped centralized laboratories for screening. A rapid point-of-care test is needed to allow more widespread mobile detection of the virus directly from patient material. In this study, we describe the development of a reverse transcription isothermal Recombinase Polymerase Amplification (RT-RPA) assay for the identification of MERS-CoV. A partial nucleocapsid gene RNA molecular standard of MERS-coronavirus was used to determine the assay sensitivity. The isothermal (42°C) MERS-CoV RT-RPA was as sensitive as real-time RT-PCR (10 RNA molecules), rapid (3-7 minutes) and mobile (using tubescanner weighing 1kg). The MERS-CoV RT-RPA showed cross-detection neither of any of the RNAs of several coronaviruses and respiratory viruses affecting humans nor of the human genome. The developed isothermal real-time RT-RPA is ideal for rapid mobile molecular MERS-CoV monitoring in acute patients and may also facilitate the search for the animal reservoir of MERS-CoV. PMID:24459611

  14. Molecular Epidemiology of Hospital Outbreak of Middle East Respiratory Syndrome, Riyadh, Saudi Arabia, 2014

    PubMed Central

    Fagbo, Shamsudeen F.; Skakni, Leila; Chu, Daniel K.W.; Garbati, Musa A.; Joseph, Mercy

    2015-01-01

    We investigated an outbreak of Middle East respiratory syndrome (MERS) at King Fahad Medical City (KFMC), Riyadh, Saudi Arabia, during March 29–May 21, 2014. This outbreak involved 45 patients: 8 infected outside KFMC, 13 long-term patients at KFMC, 23 health care workers, and 1 who had an indeterminate source of infection. Sequences of full-length MERS coronavirus (MERS-CoV) from 10 patients and a partial sequence of MERS-CoV from another patient, when compared with other MERS-CoV sequences, demonstrated that this outbreak was part of a larger outbreak that affected multiple health care facilities in Riyadh and possibly arose from a single zoonotic transmission event that occurred in December 2013 (95% highest posterior density interval November 8, 2013–February 10, 2014). This finding suggested continued health care–associated transmission for 5 months. Molecular epidemiology documented multiple external introductions in a seemingly contiguous outbreak and helped support or refute transmission pathways suspected through epidemiologic investigation. PMID:26484549

  15. Water Clarity Simulant for K East Basin Filtration Testing

    SciTech Connect

    Schmidt, Andrew J.

    2006-01-20

    This document provides a simulant formulation intended to mimic the behavior of the suspended solids in the K East (KE) Basin fuel storage pool. The simulant will be used to evaluate alternative filtration apparatus to improve Basin water clarity and to possibly replace the existing sandfilter. The simulant was formulated based on the simulant objectives, the key identified parameters important to filtration, the composition and character of the KE Basin suspended sludge particles, and consideration of properties of surrogate materials.

  16. Fish community diversity in the middle continental shelf of the East China Sea

    NASA Astrophysics Data System (ADS)

    Shan, Xiujuan; Jin, Xianshi; Zhou, Zhipeng; Dai, Fangqun

    2011-11-01

    The status of fishery stocks in the coastal waters of China is far from ideal, mainly due to climate change and the impacts of human activities (e.g., pollution and overfishing). Thus, the restoration and protection of fishery resources have become critical and complex. The stability and balanced structure of the fish community is a basic foundation for the protection of fishery resources. Based on data collected from bottom trawls by the R/V Beidou in continental shelf of the East China Sea in November 2006 and February 2007, changes in the composition and diversity of fish species and functional groups were analyzed. The research area was divided into offshore waters and inshore waters by the two-way indicator species analysis (TWIA). The results showed that the dominant species were different between offshore waters and inshore waters and also varied with the survey time. The most abundant family was Sciaenidae and Teraponidae in November 2006, Sciaenidae, Engraulidae and Triglidae were most abundant in February 2007. The species belonged mainly to mobile piscivores (G6), benthivores/piscivores (G4), benthivores (G3) and planktivores (G1), and the dominant species in November 2006 were commercial species (e.g. Larimichthys polyactis and Trichiurus japonicus), but small-sized species were dominant in February 2007 (e.g., Harpadon nehereus, Benthosema pterotum, Champsodon capensis, and Acropoma japonicum). The species diversity showed a similar trend as the functional group diversity. Stations with higher diversity were mainly distributed in inshore waters in February 2007, whereas higher diversity was found in offshore waters in November 2006. The highest biomass and species number were found in G6 group, followed by the G4, G5 and G1 groups. The distribution of the number of individuals of each functional group showed the opposite trend as that of the biomass distribution. In addition, the size spectra were mainly concentrated around 3-29 cm, and the individual

  17. [Remarks concerning risk of infections and health service infrastructure in countries of the Middle East with Syria, for example].

    PubMed

    Korzeniewski, Krzysztof

    2006-01-01

    Assessment of epidemiological situation in the Middle East, in the Mediterranean Sea basin, based on the status of the Syrian health service and diseases occurring among society of this country within the space of the last tens of years is presented in this article. Knowledge of morbidity and morbidness of Syrians, representatives of Arab-Muslim community is relatively low. First of all, it is related to isolation of Syria in the international arena, poor status of education and health service, lack of current epidemiological data on health condition of the country population. Knowledge of issues mentioned above has essential importance for people working or serving in Syria (military and civilian UN personnel), as well as for tourists travelling in the Middle East.

  18. Emergence of antigenic variants within serotype A FMDV in the Middle East with antigenically critical amino acid substitutions.

    PubMed

    Mahapatra, Mana; Statham, Bob; Li, Yanmin; Hammond, Jef; Paton, David; Parida, Satya

    2016-06-01

    A new immunologically distinct strain (A-Iran-05) of foot-and-mouth disease virus serotype A emerged in the Middle East in 2003 that replaced the previously circulating strains (A-Iran-96 and A-Iran-99) in the region. This resulted in introduction of a new vaccine of this strain (A/TUR/2006) in 2006. Though this vaccine strain has been predominantly used to control FMD in the region, recent viruses isolated in 2012 and 2013 have shown antigenic drift and a poor match with it. In this study, we report the antigenic matching results and capsid sequence data of currently circulating viruses belonging to the SIS-10 and SIS-12 sub-lineages of A-Iran-05 (isolated in 2012 and 2013), highlighting the inadequacy of the currently used serotype A vaccines. Implications of these results in the context of FMD control in the Middle East are discussed. PMID:27016651

  19. Overview of preparedness and response for Middle East respiratory syndrome coronavirus (MERS-CoV) in Oman.

    PubMed

    Al-Abaidani, I S; Al-Maani, A S; Al-Kindi, H S; Al-Jardani, A K; Abdel-Hady, D M; Zayed, B E; Al-Harthy, K S; Al-Shaqsi, K H; Al-Abri, S S

    2014-12-01

    Several countries in the Middle East and around 22 countries worldwide have reported cases of human infection with the Middle East respiratory syndrome coronavirus (MERS-CoV). The exceptionally high fatality rate resulting from MERS-CoV infection in conjunction with the paucity of knowledge about this emerging virus has led to major public and international concern. Within the framework of the national acute respiratory illness surveillance, the Ministry of Health in the Sultanate of Oman has announced two confirmed cases of MERS-CoV to date. The aim of this report is to describe the epidemiological aspects of these two cases and to highlight the importance of public health preparedness and response. The absence of secondary cases among contacts of the reported cases can be seen as evidence of the effectiveness of infection prevention and control precautions as an important pillar of the national preparedness and response plan applied in the health care institutions in Oman. PMID:25447719

  20. Risks of Death and Severe Disease in Patients With Middle East Respiratory Syndrome Coronavirus, 2012-2015.

    PubMed

    Rivers, Caitlin M; Majumder, Maimuna S; Lofgren, Eric T

    2016-09-15

    Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging pathogen, first recognized in 2012, with a high case fatality risk, no vaccine, and no treatment beyond supportive care. We estimated the relative risks of death and severe disease among MERS-CoV patients in the Middle East between 2012 and 2015 for several risk factors, using Poisson regression with robust variance and a bootstrap-based expectation maximization algorithm to handle extensive missing data. Increased age and underlying comorbidity were risk factors for both death and severe disease, while cases arising in Saudi Arabia were more likely to be severe. Cases occurring later in the emergence of MERS-CoV and among health-care workers were less serious. This study represents an attempt to estimate risk factors for an emerging infectious disease using open data and to address some of the uncertainty surrounding MERS-CoV epidemiology. PMID:27608662

  1. Milankovitch forcing and role of Indonesian Gateway on middle Miocene climate and carbon cycle: New perspective from the South China Sea, equatorial West Pacific and East Indian Ocean

    NASA Astrophysics Data System (ADS)

    Holbourn, A.; Kuhnt, W.; Schulz, M.

    2003-04-01

    The enigmatic long-term positive carbon isotope excursion ("Monterey excursion") in the middle Miocene exhibits an apparent 400 ky cyclicity (long eccentricity cycle of the Milankovitch frequency band). Similar isotope excursion are known from the mid-Cretaceous and may be a characteristic feature of a greenhouse world with extreme warm climate, high sealevel, and a dominantly zonal circulation pattern in the world ocean. This period of extreme warmth (the mid-Miocene climate optimum) ended between 14.2 and 13.8 Ma, when a significant increase in deep-water oxygen isotopic values occurred that was related to the growth of the East Antarctic ice sheet. Plate tectonic movements between Australia and SE Asia, ultimately leading to the closure of the deep water gateway connecting the Indian and Pacific Oceans, started prior to this paleoceanographic change. We used benthic deep water oxygen and carbon isotope curves in combination with new age models at critical locations along the northern margin of the Indonesian Gateway (South China Sea, ODP Site 1146), at the western end of the gateway (NW Australian margin, ODP Site 761) and at the eastern end of the gateway (Ontong Java Plateau, ODP Site 806) to investigate the frequency and amplitude of deep water isotope fluctuations during the middle Miocene. High resolution sediment color reflectance data, benthic carbon isotopes and foraminiferal assemblages are used as proxies of deep-water ventilation and carbon flux. Our results indicate Milankovitch forcing on virtually all proxies and a change from eccentricity to precession driven cyclicity at approximately 15 Ma. Our data reveal increased carbon flux and a restricted deep water exchange between the Pacific Ocean and Indian Ocean through the Indonesian Gateway during the middle Miocene climate optimum. After 13.6 Ma, the decrease in d13C was strongest at Site 806, indicating a marked change in the deep-water circulation of the equatorial West Pacific and a switch to a

  2. Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary Camels.

    PubMed

    Widagdo, W; Raj, V Stalin; Schipper, Debby; Kolijn, Kimberley; van Leenders, Geert J L H; Bosch, Berend J; Bensaid, Albert; Segalés, Joaquim; Baumgärtner, Wolfgang; Osterhaus, Albert D M E; Koopmans, Marion P; van den Brand, Judith M A; Haagmans, Bart L

    2016-05-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) is not efficiently transmitted between humans, but it is highly prevalent in dromedary camels. Here we report that the MERS-CoV receptor--dipeptidyl peptidase 4 (DPP4)--is expressed in the upper respiratory tract epithelium of camels but not in that of humans. Lack of DPP4 expression may be the primary cause of limited MERS-CoV replication in the human upper respiratory tract and hence restrict transmission.

  3. A note on the discovery of the suturocavate dinoflagellate cyst (Limbodinium absidatum) in the Middle East (Binalud Mountains, NE Iran)

    NASA Astrophysics Data System (ADS)

    Mafi, Abradat; Ghasemi-Nejad, Ebrahim; Ashouri, Alireza; Vahidi-Nia, Mohammad

    2014-04-01

    Limbodinium absidatum is a suturocavate dinocyst that is being reported here from the Binalud Mountains, NE Iran, which is also the first record of this rare species from the Middle East. A few specimens of L. absidatum are recorded from samples taken from the Dalichai Formation at a section measured at Ghoroneh. The stratigraphic range of this species (Late Callovian-Early Oxfordian) is very important for Jurassic palynologists. Morphological characteristics of this Sexiform species are described in detail to support the identification.

  4. Security implications of the proliferation of weapons of mass destruction (WMD) in the Middle East. Research report

    SciTech Connect

    Hajjar, S.G.

    1998-12-17

    This paper concerns the underlying dynamic of the proliferation of weapons of mass destruction (WMD) in the Middle East. It will seek to explain the quest to proliferation in terms of the interconnectivity and the region, the motivations of the major regional powers, and local perceptions as to the nature of security threats. Finally, the paper will discuss the implications of proliferation for US policy toward the region that may require a shift in that policy.

  5. Complex Epidemiology of a Zoonotic Disease in a Culturally Diverse Region: Phylogeography of Rabies Virus in the Middle East

    PubMed Central

    Horton, Daniel L.; McElhinney, Lorraine M.; Freuling, Conrad M.; Marston, Denise A.; Banyard, Ashley C.; Goharrriz, Hooman; Wise, Emma; Breed, Andrew C.; Saturday, Greg; Kolodziejek, Jolanta; Zilahi, Erika; Al-Kobaisi, Muhannad F.; Nowotny, Norbert; Mueller, Thomas; Fooks, Anthony R.

    2015-01-01

    The Middle East is a culturally and politically diverse region at the gateway between Europe, Africa and Asia. Spatial dynamics of the fatal zoonotic disease rabies among countries of the Middle East and surrounding regions is poorly understood. An improved understanding of virus distribution is necessary to direct control methods. Previous studies have suggested regular trans-boundary movement, but have been unable to infer direction. Here we address these issues, by investigating the evolution of 183 rabies virus isolates collected from over 20 countries between 1972 and 2014. We have undertaken a discrete phylogeographic analysis on a subset of 139 samples to infer where and when movements of rabies have occurred. We provide evidence for four genetically distinct clades with separate origins currently circulating in the Middle East and surrounding countries. Introductions of these viruses have been followed by regular and multidirectional trans-boundary movements in some parts of the region, but relative isolation in others. There is evidence for minimal regular incursion of rabies from Central and Eastern Asia. These data support current initiatives for regional collaboration that are essential for rabies elimination. PMID:25811659

  6. Assessment of the risk posed to Singapore by the 2015 Middle East respiratory syndrome outbreak in the Republic of Korea

    PubMed Central

    Zhang, Emma Xuxiao; Oh, Olivia Seen Huey; See, Wanhan; Raj, Pream; James, Lyn; Khan, Kamran

    2016-01-01

    Objective To assess the public health risk to Singapore posed by the Middle East respiratory syndrome (MERS) outbreak in the Republic of Korea in 2015. Methods The likelihood of importation of MERS cases and the magnitude of the public health impact in Singapore were assessed to determine overall risk. Literature on the epidemiology and contextual factors associated with MERS coronavirus infection was collected and reviewed. Connectivity between the Republic of Korea and Singapore was analysed. Public health measures implemented by the two countries were reviewed. Results The epidemiology of the 2015 MERS outbreak in the Republic of Korea remained similar to the MERS outbreaks in Saudi Arabia. In addition, strong infection control and response measures were effective in controlling the outbreak. In view of the air traffic between Singapore and MERS-affected areas, importation of MERS cases into Singapore is possible. Nonetheless, the risk of a serious public health impact to Singapore in the event of an imported case of MERS would be mitigated by its strong health-care system and established infection control practices. Discussion The MERS outbreak was sparked by an exported case from the Middle East, which remains a concern as the reservoir of infection (thought to be camels) continues to exist in the Middle East, and sporadic cases in the community and outbreaks in health-care settings continue to occur there. This risk assessment highlights the need for Singapore to stay vigilant and to continue enhancing core public health capacities to detect and respond to MERS coronavirus. PMID:27508087

  7. Woods to sand: Operational considerations for the employment of a European base division in a contingency in the Middle East

    SciTech Connect

    Townsend, J.

    1991-05-29

    This monograph examines the employment of a European based U.S. heavy division in a contingency in the Middle East. Applicable theory is described and developed against the historical lens of armored campaigns in desert regions and then is used to develop the research paper's product: employment considerations. The strategic setting of the Middle East demands sustained attention from the United States. We can expect continued trouble and violence resulting from the diverse religious, cultural, economic, and military pressures within the area. We will most likely see United States interests in protecting sovereign nations and encouraging peace in the region. Since the diminished Soviet threat in Europe no longer fixes divisions in position, a heavy division could be available for employment in the adjacent theater, the Middle East. The criteria introduced to develop the analysis are the dynamics of combat power: maneuver, firepower, protection and leadership. These are examined from theoretical and historical frames of reference that include the German World War II North African campaign, Arab-Israeli wars, and the recent Iran-Iraq War.

  8. Automated inter-station phase velocity measurements across the eastern Mediterranean and Middle East

    NASA Astrophysics Data System (ADS)

    El-Sharkawy, Amr; Weidle, Christian; Christiano, Luigia; Soomro, Riaz; Lebedev, Sergi; Meier, Thomas

    2016-04-01

    The structure of the lithosphere in northeastern Africa, eastern Mediterranean and the Middle East is highly variable. It ranges from young oceanic lithosphere in the Red Sea to what is considered the oldest oceanic lithosphere on Earth in the Mediterranean Sea north of Libya, and from highly deformed continental lithosphere at the east-Mediterranean margins to more stable continental lithosphere of Phanerozoic origin and to cratonic lithosphere beneath the Arabian Peninsula. Details of the lithospheric structure are, however, poorly known. Surface waves are ideally suited for studies of the lithosphere and the sublithospheric mantle. Our goal is to better define the 3D lithospheric shear-wave velocity structure within this region by surface wave tomography. Using regional to teleseismic Rayleigh and Love waves that traverse the area we can obtain information about its seismic structure by examining phase velocities as a function of frequency. A newly developed algorithm for automated inter-station phase velocity measurements (Soomro et al. 2016) is applied here to obtain both Rayleigh and Love fundamental mode phase velocities. We utilize a database consisting of more than 3800 regional and teleseismic earthquakes recorded by more than 1850 broadband seismic stations within the area, provided by the European Integrated Data Archive (WebDc/EIDA) and IRIS. Moreover, for the first time, data from the Egyptian National Seismological Network (ENSN), recorded by up to 25 broad band seismic stations, is also included in the analysis. For each station pair approximately located on the same great circle path, the recorded waveforms are cross correlated and the dispersion curves of fundamental modes are calculated from the phase of the weighted cross correlation functions. Path average dispersion curves are obtained by averaging the smooth parts of single-event dispersion curves. Parameters tests and preliminary results of automatically measured phase velocities are

  9. Wave of Middle East migration raises questions of policy in many countries.

    PubMed

    Gerakis, A S; Thayanithy, S

    1978-09-01

    Since 1973 the increase in revenues from petroleum has resulted in a substantial migration of workers to the oil exporting countries of the Middle East. Discussion focuses on the policies being used to minimize the costs and maximize the advantages of emigration, including description and evaluation of measures and proposals for further action. No action seems to have been taken to regulate the present wave of Middle Eastern emigration, probably because in its initial stages it proved an unmixed blessing for the labor exporting countries. Steps should have been taken to protect the emigrants. Their living conditions are unsatisfactory in some host countries, and frequently they are exploited by the unscrupulous middlemen who arranged their employment and wages. No effective international agreements, multilateral or bilateral, have been concluded to deal with these problems. A policy response is required as labor shortages emerge in the later phases of emigration, especially as the balance of payments situation improves and reserves rise. An appropriate strategy should combine both supply and demand management measures. It should avoid overambitious antiinflationary objectives. For the majority of the labor exporting countries discussed here, foreign exchange earnings from migrants have reached sizable amounts, exceeding, for example, $1 billion in Egypt, India, Pakistan, and the Yemen Arab Republic. Countries are maximizing those receipts by resorting to compulsion and surrender requirements. Emigrants should be coaxed and not compelled to remit currently a high proportion of savings and to invest a low percentage in the country where they work or in 3rd countries. Remittances by workers during the period of their stay in foreign countries are made for family maintenance and for investment. The most effective way to satisfy emigrants that they will be able to reexport their assets is to remove all restrictions on payments. Going beyond general policies to create a

  10. Wave of Middle East migration raises questions of policy in many countries.

    PubMed

    Gerakis, A S; Thayanithy, S

    1978-09-01

    Since 1973 the increase in revenues from petroleum has resulted in a substantial migration of workers to the oil exporting countries of the Middle East. Discussion focuses on the policies being used to minimize the costs and maximize the advantages of emigration, including description and evaluation of measures and proposals for further action. No action seems to have been taken to regulate the present wave of Middle Eastern emigration, probably because in its initial stages it proved an unmixed blessing for the labor exporting countries. Steps should have been taken to protect the emigrants. Their living conditions are unsatisfactory in some host countries, and frequently they are exploited by the unscrupulous middlemen who arranged their employment and wages. No effective international agreements, multilateral or bilateral, have been concluded to deal with these problems. A policy response is required as labor shortages emerge in the later phases of emigration, especially as the balance of payments situation improves and reserves rise. An appropriate strategy should combine both supply and demand management measures. It should avoid overambitious antiinflationary objectives. For the majority of the labor exporting countries discussed here, foreign exchange earnings from migrants have reached sizable amounts, exceeding, for example, $1 billion in Egypt, India, Pakistan, and the Yemen Arab Republic. Countries are maximizing those receipts by resorting to compulsion and surrender requirements. Emigrants should be coaxed and not compelled to remit currently a high proportion of savings and to invest a low percentage in the country where they work or in 3rd countries. Remittances by workers during the period of their stay in foreign countries are made for family maintenance and for investment. The most effective way to satisfy emigrants that they will be able to reexport their assets is to remove all restrictions on payments. Going beyond general policies to create a

  11. Redescription of Protanura papillata Cassagnau & Delamare Deboutteville, 1955 (Collembola, Neanuridae, Neanurinae), with new records from Middle East, and with supplemented diagnosis and key to the genus.

    PubMed

    Smolis, Adrian; Skarżyński, Dariusz; Kahrarian, Morteza; Kaprus, Ighor J

    2016-01-01

    The poorly known Neanurini genus Protanura is rediagnosed and briefly compared with Lathriopyga. Protanura papillata Cassagnau & Delamare Deboutteville, 1955, known to date only from Lebanon, is redescribed based on the lectotype and new extensive material from Middle East. PMID:27394457

  12. Characterising the progress in HIV/AIDS research in the Middle East and North Africa

    PubMed Central

    Saba, Hanan F; Kouyoumjian, Silva P; Mumtaz, Ghina R; Abu-Raddad, Laith J

    2013-01-01

    Objectives The Middle East and North Africa (MENA) region is perceived to have limited HIV data. The objective of this study was to quantitatively characterise the progress in HIV research in this region since the discovery of the epidemic. Methods Four indices were defined and implemented to measure the progress of HIV research using the PubMed, Embase, MENA HIV/AIDS Epidemiology Synthesis Project and US Census Bureau HIV/AIDS Surveillance databases. The four indices provide complementary measures to characterise different aspects of the progress of HIV research. Results A total of 2118, 2352, 683 and 4889 records were identified through the PubMed, the Embase, the Synthesis Project and the HIV Prevalence indices, respectively. The proportion of the total global HIV records that relate to MENA is 1.2%. Overall, the indices show steady progress in the number of new records every year, with an accelerated pace in the last few years. The rate of progress in MENA was also higher than the rate of progress in HIV records globally. There is no evidence so far of stabilisation or a peak in the number of new records year by year. About half of the records were produced after the year 2005. The number of records shows large heterogeneity across countries. Conclusions MENA has witnessed a rapid growth in HIV research over the last decade. However, there are still large gaps in HIV scientific evidence in the region, and the progress is far from being uniform across countries. Ongoing and future research needs to be geared towards academic standard and production of scientific publications. PMID:23596206

  13. Early initiation of antiretroviral treatment: Challenges in the Middle East and North Africa

    PubMed Central

    Sardashti, Sara; Samaei, Mehrnoosh; Firouzeh, Mona Mohammadi; Mirshahvalad, Seyed Ali; Pahlaviani, Fatemeh Golsoorat; SeyedAlinaghi, SeyedAhmad

    2015-01-01

    New World Health Organization guidelines recommend the initiation of antiretroviral treatment (ART) for asymptomatic patients with CD4+ T-cell counts of ≤ 500 cells/mm3. Substantial reduction of human immunodeficiency virus (HIV) transmission is addressed as a major public health outcome of this new approach. Middle East and North Africa (MENA), known as the area of controversies in terms of availability of comprehensive data, has shown concentrated epidemics among most of it’s at risk population groups. Serious challenges impede the applicability of new guidelines in the MENA Region. Insufficient resources restrict ART coverage to less than 14%, while only one fourth of the countries had reportable data on patients’ CD4 counts at the time of diagnosis. Clinical guidelines need to be significantly modified to reach practical utility, and surveillance systems have not yet been developed in many countries of MENA. Based on available evidence in several countries people who inject drugs and men who have sex with men are increasingly vulnerable to HIV and viral hepatitis, while their sexual partners - either female sex workers or women in monogamous relationships with high-risk men - are potential bridging populations that are not appropriately addressed by regional programs. Research to monitor the response to ART among the mentioned groups are seriously lacking, while drug resistant HIV strains and limited information on adherence patterns to treatment regimens require urgent recognition by health policymakers. Commitment to defined goals in the fight against HIV, development of innovative methods to improve registration and reporting systems, monitoring and evaluation of current programs followed by cost-effective modifications are proposed as effective steps to be acknowledged by National AIDS Programs of the countries of MENA Region. PMID:25964878

  14. Oral Health Inequalities between Rural and Urban Populations of the African and Middle East Region.

    PubMed

    Ogunbodede, E O; Kida, I A; Madjapa, H S; Amedari, M; Ehizele, A; Mutave, R; Sodipo, B; Temilola, S; Okoye, L

    2015-07-01

    Although there have been major improvements in oral health, with remarkable advances in the prevention and management of oral diseases, globally, inequalities persist between urban and rural communities. These inequalities exist in the distribution of oral health services, accessibility, utilization, treatment outcomes, oral health knowledge and practices, health insurance coverage, oral health-related quality of life, and prevalence of oral diseases, among others. People living in rural areas are likely to be poorer, be less health literate, have more caries, have fewer teeth, have no health insurance coverage, and have less money to spend on dental care than persons living in urban areas. Rural areas are often associated with lower education levels, which in turn have been found to be related to lower levels of health literacy and poor use of health care services. These factors have an impact on oral health care, service delivery, and research. Hence, unmet dental care remains one of the most urgent health care needs in these communities. We highlight some of the conceptual issues relating to urban-rural inequalities in oral health, especially in the African and Middle East Region (AMER). Actions to reduce oral health inequalities and ameliorate rural-urban disparity are necessary both within the health sector and the wider policy environment. Recommended actions include population-specific oral health promotion programs, measures aimed at increasing access to oral health services in rural areas, integration of oral health into existing primary health care services, and support for research aimed at informing policy on the social determinants of health. Concerted efforts must be made by all stakeholders (governments, health care workforce, organizations, and communities) to reduce disparities and improve oral health outcomes in underserved populations. PMID:26101336

  15. Rapid generation of a mouse model for Middle East respiratory syndrome

    PubMed Central

    Zhao, Jincun; Li, Kun; Wohlford-Lenane, Christine; Agnihothram, Sudhakar S.; Fett, Craig; Zhao, Jingxian; Gale, Michael J.; Baric, Ralph S.; Enjuanes, Luis; Gallagher, Tom; McCray, Paul B.; Perlman, Stanley

    2014-01-01

    In this era of continued emergence of zoonotic virus infections, the rapid development of rodent models represents a critical barrier to public health preparedness, including the testing of antivirus therapy and vaccines. The Middle East respiratory syndrome coronavirus (MERS-CoV) was recently identified as the causative agent of a severe pneumonia. Given the ability of coronavirus to rapidly adapt to new hosts, a major public health concern is that MERS-CoV will further adapt to replication in humans, triggering a pandemic. No small-animal model for this infection is currently available, but studies suggest that virus entry factors can confer virus susceptibility. Here, we show that mice were sensitized to MERS-CoV infection by prior transduction with adenoviral vectors expressing the human host-cell receptor dipeptidyl peptidase 4. Mice developed a pneumonia characterized by extensive inflammatory-cell infiltration with virus clearance occurring 6–8 d after infection. Clinical disease and histopathological changes were more severe in the absence of type-I IFN signaling whereas the T-cell response was required for virus clearance. Using these mice, we demonstrated the efficacy of a therapeutic intervention (poly I:C) and a potential vaccine [Venezuelan equine encephalitis replicon particles expressing MERS-CoV spike protein]. We also found little protective cross-reactivity between MERS-CoV and the severe acute respiratory syndrome-CoV. Our results demonstrate that this system will be useful for MERS-CoV studies and for the rapid development of relevant animal models for emerging respiratory viral infections. PMID:24599590

  16. Hospital-Associated Outbreak of Middle East Respiratory Syndrome Coronavirus: A Serologic, Epidemiologic, and Clinical Description

    PubMed Central

    Al-Abdallat, Mohammad Mousa; Payne, Daniel C.; Alqasrawi, Sultan; Rha, Brian; Tohme, Rania A.; Abedi, Glen R.; Nsour, Mohannad Al; Iblan, Ibrahim; Jarour, Najwa; Farag, Noha H.; Haddadin, Aktham; Al-Sanouri, Tarek; Tamin, Azaibi; Harcourt, Jennifer L.; Kuhar, David T.; Swerdlow, David L.; Erdman, Dean D.; Pallansch, Mark A.; Haynes, Lia M.; Gerber, Susan I.

    2015-01-01

    Background In April 2012, the Jordan Ministry of Health investigated an outbreak of lower respiratory illnesses at a hospital in Jordan; 2 fatal cases were retrospectively confirmed by real-time reverse transcription polymerase chain reaction (rRT-PCR) to be the first detected cases of Middle East respiratory syndrome (MERS-CoV). Methods Epidemiologic and clinical characteristics of selected potential cases were assessed through serum blood specimens, medical record reviews, and interviews with surviving outbreak members, household contacts, and healthcare personnel. Cases of MERS-CoV infection were identified using 3 US Centers for Disease Control and Prevention serologic tests for detection of anti–MERS-CoV antibodies. Results Specimens and interviews were obtained from 124 subjects. Seven previously unconfirmed individuals tested positive for anti–MERS-CoV antibodies by at least 2 of 3 serologic tests, in addition to 2 fatal cases identified by rRT-PCR. The case-fatality rate among the 9 total cases was 22%. Six subjects were healthcare workers at the outbreak hospital, yielding an attack rate of 10% among potentially exposed outbreak hospital personnel. There was no evidence of MERS-CoV transmission at 2 transfer hospitals having acceptable infection control practices. Conclusions Novel serologic tests allowed for the detection of otherwise unrecognized cases of MERS-CoV infection among contacts in a Jordanian hospital-associated respiratory illness outbreak in April 2012, resulting in a total of 9 test-positive cases. Serologic results suggest that further spread of this outbreak to transfer hospitals did not occur. Most subjects had no major, underlying medical conditions; none were on hemodialysis. Our observed case-fatality rate was lower than has been reported from outbreaks elsewhere. PMID:24829216

  17. Smoking habits in the Middle East and North Africa: results of the BREATHE study.

    PubMed

    Khattab, Adel; Javaid, Arshad; Iraqi, Ghali; Alzaabi, Ashraf; Ben Kheder, Ali; Koniski, Marie-Louise; Shahrour, Naem; Taright, Samya; Idrees, Magdy; Polatli, Mehmet; Rashid, Nauman; El Hasnaoui, Abdelkader

    2012-12-01

    Few recent comparative data exist on smoking habits in the Middle East and North Africa (MENA) region. The objective of this analysis was to evaluate smoking patterns in a large general population sample of individuals aged ≥ 40 years in ten countries in the region (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arabia, Syria, Tunisia, Turkey and United Arab Emirates), together with Pakistan, using a standardised methodology. A random sample of 457,258 telephone numbers was generated and called. This identified 65,154 eligible subjects, of whom 62,086 agreed to participate. A screening questionnaire was administered to each participant, which included six questions relating to cigarette consumption and waterpipe use. The age- and gender-adjusted proportion of respondents reporting current or past smoking of cigarettes or waterpipes was 31.2% [95% CI: 30.9-31.6%]. This proportion was significantly higher (p < 0.001) in men (48.0%) than in women (13.8%), but no relevant differences were observed between age groups. Smoking rates were in general lowest in the Maghreb countries and Pakistan and highest in the Eastern Mediterranean countries, ranging from 15.3% in Morocco to 53.9% in Lebanon. Consumption rates were 28.8% [28.4-29.2%] for cigarette smoking and 3.5% [3.4-3.6%] for waterpipe use. Use of waterpipes was most frequent in Saudi Arabia (8.5% of respondents) but remained low in the Maghreb countries (< 1.5%). Cumulative cigarette exposure was high, with a mean number of pack · years smoked of 18.5 ± 20.5 for women and 29.1 ± 26.2 for men. In conclusion, smoking is a major health issue in the MENA region.

  18. Climatology and dynamics of summer tropopause folds over the eastern Mediterranean and the Middle East

    NASA Astrophysics Data System (ADS)

    Tyrlis, E.; Skerlak, B.; Sprenger, M.; Wernli, H.; Zittis, G.; Lelieveld, J.

    2013-12-01

    A climatology of tropopause folds is presented that focus on the summer events occurring over the Eastern Mediterranean and the Middle East (EMME) based on the ERA-Interim dataset. The methodology employs an algorithm that detects folds as areas featuring multiple crossings of the dynamical tropopause and allows their classification according to their vertical extent. Our results confirm the findings of an earlier 1-year climatology that recognized a global ';hot spot' of fold activity over a sector extending from the eastern Mediterranean to Afghanistan, in the vicinity of the subtropical jet. Two distinct maxima of activity are recognized over Turkey and Iran-Afghanistan where fold occurrence exceeds 25%. Rarely, deep folds form over the Levantine Basin and Iran at surprising low latitudes. This summertime increase in fold activity defies the zonal mean seasonal cycle over the subtropics and it is driven by the South Asian Monsoon. From late spring, the EMME is gradually brought under the influence of the zonally asymmetric background state induced by the monsoon, which features an elevated tropopause and depression of isentropic surfaces. As areas of sharply sloping isentropes develop especially over the eastern Mediterranean and Iran-Afghanistan, subsidence and fold formation are favored. The monsoon also drives the interannual variability of EMME fold activity. An upward trend in fold activity is identified, especially during May that can be attributed to the recent advanced monsoon onset and the deeper convective activity throughout summer. This stronger upper level monsoon signature promotes enhanced upper level baroclinicity over the EMME that favors folding.

  19. Middle East respiratory syndrome coronavirus (MERS-CoV): what lessons can we learn?

    PubMed

    Omrani, A S; Shalhoub, S

    2015-11-01

    The Middle East Respiratory Coronavirus (MERS-CoV) was first isolated from a patient who died with severe pneumonia in June 2012. As of 19 June 2015, a total of 1,338 MERS-CoV infections have been notified to the World Health Organization (WHO). Clinical illness associated with MERS-CoV ranges from mild upper respiratory symptoms to rapidly progressive pneumonia and multi-organ failure. A significant proportion of patients present with non-respiratory symptoms such as headache, myalgia, vomiting and diarrhoea. A few potential therapeutic agents have been identified but none have been conclusively shown to be clinically effective. Human to human transmission is well documented, but the epidemic potential of MERS-CoV remains limited at present. Healthcare-associated clusters of MERS-CoV have been responsible for the majority of reported cases. The largest outbreaks have been driven by delayed diagnosis, overcrowding and poor infection control practices. However, chains of MERS-CoV transmission can be readily interrupted with implementation of appropriate control measures. As with any emerging infectious disease, guidelines for MERS-CoV case identification and surveillance evolved as new data became available. Sound clinical judgment is required to identify unusual presentations and trigger appropriate control precautions. Evidence from multiple sources implicates dromedary camels as natural hosts of MERS-CoV. Camel to human transmission has been demonstrated, but the exact mechanism of infection remains uncertain. The ubiquitously available social media have facilitated communication and networking amongst healthcare professionals and eventually proved to be important channels for presenting the public with factual material, timely updates and relevant advice. PMID:26452615

  20. Stem cell course in the Middle East: science diplomacy and international collaborations during the Arab spring.

    PubMed

    Sarkadi, Balazs; Schatten, Gerald

    2012-03-01

    In April 2011, an international advanced course and workshop entitled "Frontiers in Human Pluripotent Stem Cells" and an International Congress on Fertility and Genetics ( http://www.fertigen.com.jo/ConferenceDetails.aspx ) was held in Amman Jordan hosted by the Jordanian Society of Fertility and Genetics under the auspices of the International Cell Research Organization (ICRO), a UNESCO associated NGO. The Congress President Dr. Zaid Kilani, with Dr. Abdel Latif Abu Khadra, President of the Jordanian society for Fertility and Genetics, Dr. Rana Dajani of the Hashemite University of Jordan, and their Organizing Committee proved to be an excellent organizers and dedicated physician-scientists and, focusing on fertility, genetics and stem cells in a wide range of advanced therapeutic applications. Brilliant course participants included trainees, scientists and clinicians from the Greater Middle East. The lectures and practical sessions, presented by internationally acknowledged scientists, included overviews of recent achievements in pluripotent stem cell research, emphasizing the role of both the embryonic (ES) and induced pluripotent stem (iPS) cells. A major emphasis was placed on the clinical achievements in germ cell and umbilical cord stem cell transplantation issues, and on the potential of fast and successful prenatal and pre-implantation molecular genetics diagnostics. The organization of the stem cell course in the Holy Land especially emphasized that issues of "eternal life" and "rejuvenation" are already at hand--at least in the pluripotent stem cell research field. In the lively atmosphere of the course about 60 participants had heated discussions on the possibility and ethics of advanced prenatal diagnostics, and on regulatory issues reflecting the need of separation of clinically effective versus unapproved, unwarranted stem cell treatments. An open discussion of many ethical issues, reflecting profound differences in religion and medical tradition in

  1. Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus

    PubMed Central

    Cotten, Matthew; Watson, Simon J.; Zumla, Alimuddin I.; Makhdoom, Hatem Q.; Palser, Anne L.; Ong, Swee Hoe; Al Rabeeah, Abdullah A.; Alhakeem, Rafat F.; Assiri, Abdullah; Al-Tawfiq, Jaffar A.; Albarrak, Ali; Barry, Mazin; Shibl, Atef; Alrabiah, Fahad A.; Hajjar, Sami; Balkhy, Hanan H.; Flemban, Hesham; Rambaut, Andrew; Kellam, Paul; Memish, Ziad A.

    2014-01-01

    ABSTRACT The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality. In this study, we have determined the MERS-CoV evolutionary rate, documented genetic variants of the virus and their distribution throughout the Arabian peninsula, and identified the genome positions under positive selection, important features for monitoring adaptation of MERS-CoV to human transmission and for identifying the source of infections. Respiratory samples from confirmed KSA MERS cases from May to September 2013 were subjected to whole-genome deep sequencing, and 32 complete or partial sequences (20 were ≥99% complete, 7 were 50 to 94% complete, and 5 were 27 to 50% complete) were obtained, bringing the total available MERS-CoV genomic sequences to 65. An evolutionary rate of 1.12 × 10−3 substitutions per site per year (95% credible interval [95% CI], 8.76 × 10−4; 1.37 × 10−3) was estimated, bringing the time to most recent common ancestor to March 2012 (95% CI, December 2011; June 2012). Only one MERS-CoV codon, spike 1020, located in a domain required for cell entry, is under strong positive selection. Four KSA MERS-CoV phylogenetic clades were found, with 3 clades apparently no longer contributing to current cases. The size of the population infected with MERS-CoV showed a gradual increase to June 2013, followed by a decline, possibly due to increased surveillance and infection control measures combined with a basic reproduction number (R0) for the virus that is less than 1. PMID:24549846

  2. Mantle convection in the Middle East: Reconciling Afar upwelling, Arabia indentation and Aegean trench rollback

    NASA Astrophysics Data System (ADS)

    Faccenna, Claudio; Becker, Thorsten W.; Jolivet, Laurent; Keskin, Mehmet

    2013-08-01

    The Middle East region represents a key site within the Tethyan domain where continental break-up, collision, backarc extension and escape tectonics are kinematically linked together. We perform global mantle circulation computations to test the role of slab pull and mantle upwellings as driving forces for the kinematics of the Arabia-Anatolia-Aegean (AAA) system, evaluating different boundary conditions and mantle density distributions as inferred from seismic tomography or slab models. Model results are compared with geodetically inferred crustal motions, residual topography, and shear wave splitting measurements. The AAA velocity field with respect to Eurasia shows an anti-clockwise toroidal pattern, with increasing velocities toward the Aegean trench. The best match to these crustal motions can be obtained by combining the effect of slab pull exerted in the Aegean with a mantle upwelling underneath Afar and, more generally, with the large-scale flow associated with a whole mantle, Tethyan convection cell. Neogene volcanism for AAA is widespread, not only in the extensional or subduction settings, but also within plates, such as in Syria-Jordan-Israel and in Turkey, with geochemical fingerprints similar of those of the Afar lava. In addition, morphological features show large uplifting domains far from plate boundaries. We speculate that the tectonic evolution of AAA is related to the progressive northward entrainment of upwelling mantle material, which is itself associated with the establishment of the downwelling part of a convection cell through the segmented Tethyan slab below the northern Zagros and Bitlis collision zone. The recently established westward flow dragged Anatolia and pushed the Aegean slab south-westward, thus accelerating backarc extension. Our model reconciles Afar plume volcanism, the collision in the Bitlis mountains and northern Zagros, and the rapid increase of Aegean trench rollback in a single coherent frame of large scale mantle

  3. Middle East respiratory syndrome coronavirus (MERS-CoV): animal to human interaction.

    PubMed

    Omrani, Ali S; Al-Tawfiq, Jaffar A; Memish, Ziad A

    2015-01-01

    The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel enzootic betacoronavirus that was first described in September 2012. The clinical spectrum of MERS-CoV infection in humans ranges from an asymptomatic or mild respiratory illness to severe pneumonia and multi-organ failure; overall mortality is around 35.7%. Bats harbour several betacoronaviruses that are closely related to MERS-CoV but more research is needed to establish the relationship between bats and MERS-CoV. The seroprevalence of MERS-CoV antibodies is very high in dromedary camels in Eastern Africa and the Arabian Peninsula. MERS-CoV RNA and viable virus have been isolated from dromedary camels, including some with respiratory symptoms. Furthermore, near-identical strains of MERS-CoV have been isolated from epidemiologically linked humans and camels, confirming inter-transmission, most probably from camels to humans. Though inter-human spread within health care settings is responsible for the majority of reported MERS-CoV cases, the virus is incapable at present of causing sustained human-to-human transmission. Clusters can be readily controlled with implementation of appropriate infection control procedures. Phylogenetic and sequencing data strongly suggest that MERS-CoV originated from bat ancestors after undergoing a recombination event in the spike protein, possibly in dromedary camels in Africa, before its exportation to the Arabian Peninsula along the camel trading routes. MERS-CoV serosurveys are needed to investigate possible unrecognized human infections in Africa. Amongst the important measures to control MERS-CoV spread are strict regulation of camel movement, regular herd screening and isolation of infected camels, use of personal protective equipment by camel handlers and enforcing rules banning all consumption of unpasteurized camel milk and urine. PMID:26924345

  4. A Bibliometric Analysis of PubMed Literature on Middle East Respiratory Syndrome.

    PubMed

    Wang, Zhengting; Chen, Yongdi; Cai, Gaofeng; Jiang, Zhenggang; Liu, Kui; Chen, Bin; Jiang, Jianmin; Gu, Hua

    2016-01-01

    Middle East Respiratory Syndrome (MERS), a pandemic threat to human beings, has aroused huge concern worldwide, but no bibliometric studies have been conducted on MERS research. The aim of this study was to map research productivity on the disease based on the articles indexed in PubMed. The articles related to MERS dated from 2012 to 2015 were retrieved from PubMed. The articles were classified into three categories according to their focus. Publication outputs were assessed and frequently used terms were mapped using the VOS viewer software. A total of 443 articles were included for analysis. They were published in 162 journals, with Journal of Virology being the most productive (44 articles; 9.9%) and by six types of organizations, with universities being the most productive (276 articles; 62.4%).The largest proportion of the articles focused on basic medical sciences and clinical studies (47.2%) and those on prevention and control ranked third (26.2%), with those on other focuses coming in between (26.6%). The articles on prevention and control had the highest mean rank for impact factor (IF) (226.34), followed by those on basic medical sciences and clinical studies (180.23) and those on other focuses (168.03). The mean rank differences were statistically significant (p = 0.000). Besides, "conronavirus", "case", "transmission" and "detection" were found to be the most frequently used terms. The findings of this first bibliometric study on MERS suggest that the prevention and control of the disease has become a big concern and related research should be strengthened. PMID:27304963

  5. Demographic research in the Arab Middle East: opportunities, barriers, and prospects.

    PubMed

    Weller, R H

    1981-06-01

    The demographic characteristics of the Arab region that present opportunities for population research are described, and existing obstacles to research are discussed. Additionally, the prospects for improving the situation are explored. The combination of high fertility, moderately low mortality, and in some instances massive new immigration have produced extremely rapid rates of population growth. During the early 1970s the population of the United Arab Emirates increased by an annual rate of at least 15%, Qatar's population by 8.5% annually, and Kuwait's population by 6% annually. Even the labor exporting countries had high rates of population growth. Thus the slowest growth between 1970 and 1975 occurred in Yemen, where the annual rate of population growth was 1.8%. Because of the large growth gap between birth and death rates in the Arab countries, the age composition is very young. Such young age composition reduces measures of fertility and mortality that do not control for age. It also means that rapid population growth will not cease in the near future. These are the major demographic characteristics of the region and some of the major opportunities for demographic research they present. Obstacles to research in the region include the absence of a tradition of census taking or survey research for demographic purposes and the absence of a registration system for vital statistics in many of the countries. According to informed sources, the governments involved are not always supportive of research per se. Political instability often works against conducting demographic research. Another obstacle to demographic research in the Arab Middle East is language. There is a shortage of qualified instructors to teach demography in universities working in Arabic. A promising development for population research is the increase of demographic data collection by the various governments. Also, non-Arab researchers and funding organizations have expressed growing interest

  6. A Bibliometric Analysis of PubMed Literature on Middle East Respiratory Syndrome

    PubMed Central

    Wang, Zhengting; Chen, Yongdi; Cai, Gaofeng; Jiang, Zhenggang; Liu, Kui; Chen, Bin; Jiang, Jianmin; Gu, Hua

    2016-01-01

    Middle East Respiratory Syndrome (MERS), a pandemic threat to human beings, has aroused huge concern worldwide, but no bibliometric studies have been conducted on MERS research. The aim of this study was to map research productivity on the disease based on the articles indexed in PubMed. The articles related to MERS dated from 2012 to 2015 were retrieved from PubMed. The articles were classified into three categories according to their focus. Publication outputs were assessed and frequently used terms were mapped using the VOS viewer software. A total of 443 articles were included for analysis. They were published in 162 journals, with Journal of Virology being the most productive (44 articles; 9.9%) and by six types of organizations, with universities being the most productive (276 articles; 62.4%).The largest proportion of the articles focused on basic medical sciences and clinical studies (47.2%) and those on prevention and control ranked third (26.2%), with those on other focuses coming in between (26.6%). The articles on prevention and control had the highest mean rank for impact factor (IF) (226.34), followed by those on basic medical sciences and clinical studies (180.23) and those on other focuses (168.03). The mean rank differences were statistically significant (p = 0.000). Besides, “conronavirus”, “case”, “transmission” and “detection” were found to be the most frequently used terms. The findings of this first bibliometric study on MERS suggest that the prevention and control of the disease has become a big concern and related research should be strengthened. PMID:27304963

  7. Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation

    PubMed Central

    Thornbrough, Joshua M.; Jha, Babal K.; Yount, Boyd; Goldstein, Stephen A.; Li, Yize; Elliott, Ruth; Sims, Amy C.; Baric, Ralph S.; Silverman, Robert H.

    2016-01-01

    ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) is the first highly pathogenic human coronavirus to emerge since severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. Like many coronaviruses, MERS-CoV carries genes that encode multiple accessory proteins that are not required for replication of the genome but are likely involved in pathogenesis. Evasion of host innate immunity through interferon (IFN) antagonism is a critical component of viral pathogenesis. The IFN-inducible oligoadenylate synthetase (OAS)-RNase L pathway activates upon sensing of viral double-stranded RNA (dsRNA). Activated RNase L cleaves viral and host single-stranded RNA (ssRNA), which leads to translational arrest and subsequent cell death, preventing viral replication and spread. Here we report that MERS-CoV, a lineage C Betacoronavirus, and related bat CoV NS4b accessory proteins have phosphodiesterase (PDE) activity and antagonize OAS-RNase L by enzymatically degrading 2′,5′-oligoadenylate (2-5A), activators of RNase L. This is a novel function for NS4b, which has previously been reported to antagonize IFN signaling. NS4b proteins are distinct from lineage A Betacoronavirus PDEs and rotavirus gene-encoded PDEs, in having an amino-terminal nuclear localization signal (NLS) and are localized mostly to the nucleus. However, the expression level of cytoplasmic MERS-CoV NS4b protein is sufficient to prevent activation of RNase L. Finally, this is the first report of an RNase L antagonist expressed by a human or bat coronavirus and provides a specific mechanism by which this occurs. Our findings provide a potential mechanism for evasion of innate immunity by MERS-CoV while also identifying a potential target for therapeutic intervention. PMID:27025250

  8. Testing for possible cyclicity in carbonate sediments of Middle Ordovician of east Tennessee

    SciTech Connect

    Ghazizadeh, M.; Walker, K.R.

    1986-05-01

    Middle Ordovician carbonate sediments (Chickamauga Group) near Decatur, Tennessee, consist of 450 m of complex tidal-flat and subtidal sediments. Fourteen facies are recognized: (1) cherty dolostone (supratidal environment); (2) green and red silty mudstone (supratidal mud flat); (3) greenish-gray micrite-biomicrite (supratidal mud flat); (4) red silty, intrapelbiosparite-biosparite (intertidal channel); (5) green and red, loosely packed, ostracod-rich pelbiomicrite (intertidal pond); (6) stromatolitic mudstone (intertidal levee); (7) bryozoan-ostracod-brachiopod-rich pelbiomicrite (subtidal lagoon type I); (8) silty, packed pelbiomicrite-pelbiosparite (subtidal lagoon type II); (9) ostracod-gastropod-rich, bioturbated pelbiomicrite (subtidal lagoon type III); (10) bioturbated brachiopod-molluscan-rich biomicrite (subtidal lagoon type IV); (11) bioturbated green and red silty mudstone to silty sparse biomicrite (lagoon); (12) gray-tan mudstone to sparse biomicrite (quiet water, deeper subtidal lagoon); (13) intrapelbiosparite-pelbiosparite (subtidal channel); and (14) Tetradium-rich packstone (subtidal wave baffle).

  9. Ground-water contamination in East Bay Township, Michigan

    USGS Publications Warehouse

    Twenter, F.R.; Cummings, T.R.; Grannemann, N.G.

    1985-01-01

    Glacial deposits, as much as 360 feet thick, underlie the study area. The upper 29 to 118 feet, a sand and gravel unit, is the aquifer tapped by all wells in the area. This unit is underlain by impermeable clay that is at least 100 feet thick. Ground-water flow is northeastward at an estimated rate of 2 to 5 feet per day. Hydraulic conductivities in the aquifer range from 85 to 250 feet per day; 120 feet per day provided the best match of field data in a ground-water flow model. The depth to water ranged from 1 to 20 feet. Chemical analyses indicate that ground water is contaminated with organic chemicals from near the Hangar/Administration building at the U.S. Coast Guard Air Station at East Bay, about 4,300 feet northeast. The plume, which follows ground-water flow lines, ranges from 180 to 400 feet wide. In the upper reach of the plume, hydrocarbons less dense than water occur at the surface of the water table; they move downward in the aquifer as they move toward east Bay. Maximum concentrations of the major organic compounds include: benzene, 3,390 ug/L; toluene, 55,500 ug/L; xylene, 3,900 ug/L, tetrachloroethylene, 3,410 ug/L; amd bis (2-ethyl hexyl) phthalate, 2,100 ug/L. Soils are generally free of these hydrocarbons; however, in the vicinity of past drum storage, aircraft maintenance operations, and fuel storage and dispensing , as much as 1,100 ug/kg of tetrachloroethylene and 1,500 ug/kg of bis (-ethyl hexyl) phthalate were detected. At a few locations higher molecular weight hydrocarbons, characteristic of petroleum distillates were found. (USGS)

  10. Water movement in till of east-central South Dakota

    SciTech Connect

    Craven, S.J.; Ruedisili, L.C.; Barari, A.

    1985-01-01

    Factors that control the flow of water through till are poorly understood. Hydrographic analyses, field hydraulic conductivity measurements, and major-ion sampling were conducted on weathered and unweathered tills at 22 sites in east-central South Dakota. Water from a buried outwash aquifer was also chemically analyzed and carbon age dated. The upper part of most till has been weathered and exhibits extensive secondary permeability. Hydraulic conductivity values range from 10/sup -7/ to 10/sup -4/ cm/sec; typically 10 to 200 times higher than the hydraulic conductivity of unweathered till. Hydraulic gradients within weathered tills average seven times lower than within unweathered till. Water infiltrating below plant roots is believed to principally recharge and discharge the weathered till. Total dissolved solids were significantly higher in the weathered till than in the unweathered till. Water extracted from unweathered till is, in turn, up to three time higher in major-ion concentrations than water from the underlying outwash aquifer. Carbon-14 age dates from outwash aquifer water exceed 9000 years before present. Results indicate that Tittle to no water passes from the weathered till through the unweathered till into the buried outwash aquifer. Discharge from the weathered till is hypothesized to be primarily local lateral flow to sloughs, streams and ponds, combined with evapotranspiration losses during periods of high water table.

  11. Primary domestication and early uses of the emblematic olive tree: palaeobotanical, historical and molecular evidence from the Middle East.

    PubMed

    Kaniewski, David; Van Campo, Elise; Boiy, Tom; Terral, Jean-Frédéric; Khadari, Bouchaïb; Besnard, Guillaume

    2012-11-01

    Our knowledge of the origins of olive tree domestication in the Middle East and on the processes governing its extension and persistence in different vegetation types from prehistory through antiquity to modern times derives from diverse sources, spanning the biological sciences to the humanities. Nonetheless, it lacks a robust overview that may lead to floating interpretations. This is especially true in the Middle East, considered as the cradle of agriculture, and where the evolutionary history of this emblematic tree is intertwined with that of civilizations. Olive fruit, oil and wood have been, since Prehistoric times, characteristic products of the lands bordering the Mediterranean Sea. In the domestic economy of these countries, the olive tree gradually became a traditional tree crop since the first oil extraction, through the emergence of regional commerce that accompanied the rise and fall of early Near-Middle Eastern urbanism, until the development of modern trade, with an oil production estimated at circa 3000000 tons per year. The rising importance of the olive tree in human life has turned the tree into an endless source of fascination in the Aegean and Eastern Mediterranean, a symbol and a sacred tree, widely cited in the Bibles, the Koran, and in ancient literature. Here we argue that advances in radiocarbon chronology, palaeobotany, genetics, and archaeology-history have profoundly refined the history of olive trees in the Middle East. This review shows that the heartland of primary olive domestication must be enlarged to the Levant and not only focus on the Jordan Valley. The domestication of the olive tree is a long and ongoing process, linked to the early production of oil and the development of the olive trade. We also suggest that the olive tree became a particular icon, a sacred tree, during the Biblical period in the Levant.

  12. Bi-cycles petrographic association in middle part of East Pana PGE layers deposit

    NASA Astrophysics Data System (ADS)

    Asavin, Alex; Veksler, Ilya; Gorbunov, Artem

    2016-04-01

    The PGE mineralization in the East Pana layered gabbroic intrusion forms three discrete layers at different stratigraphic levels, which are traditionally labeled as zones A, B and C. In order to investigate possible relationships of mineralization with magmatic layering we sampled a 120 m long drill core section across zone B in the middle part of the intrusion and carried out detailed petrographic, mineralogical and geochemical studies of the samples. The ore zone is located in medial part of the of East's Pana deposite. The samples represent mainly from a layered sequence of gabbro and gabbro-norite. This zone is composed of interlayers of gabbroic sequences and gabbro-norite of various color, with different structures and different relationship of rock-forming minerals of Ol-Opx-Cpx-Pl. We studied one of key's drill-hole section of ore zone, in which is located two ore horizons. Fundamental feature layered intrusions are presence in cross-section cycles includes of stable petrographic association. In section of ore zone it is possible to select two most contrast petrographic types. Whole-rock analyses and petrographic observations reveal two units of modal layering comprising, from bottom to top, melanocratic gabbro grading upwards into mesocratic gabbro and gabbro-norite overlain by pegmatoidal, gabbroic rock with has sharp footwall and hanging wall contacts.There is also an olivine-bearing gabbro at the bottom of the lower unit. The ore horizons are located in same gabbro-norite type rock. The ore horizons are located in same gabbro-norite type part. The second upper ore zone located in more differential species types. There is the common trend of system evolution of well distinguished on triangle of Ol-Pl-Di, Ol-Pl-Q and other. However composition of the rocks in the two parts of our section show us similar, but independent trends. For example on diagram differentiation of rocks composition, with normative content of anorthite on the X axis, trends of

  13. Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

    PubMed Central

    Rabouw, Huib H.; Canton, Javier; Sola, Isabel; Enjuanes, Luis; Bredenbeek, Peter J.; Kikkert, Marjolein; de Groot, Raoul J.; van Kuppeveld, Frank J. M.

    2016-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe respiratory infections that can be life-threatening. To establish an infection and spread, MERS-CoV, like most other viruses, must navigate through an intricate network of antiviral host responses. Besides the well-known type I interferon (IFN-α/β) response, the protein kinase R (PKR)-mediated stress response is being recognized as an important innate response pathway. Upon detecting viral dsRNA, PKR phosphorylates eIF2α, leading to the inhibition of cellular and viral translation and the formation of stress granules (SGs), which are increasingly recognized as platforms for antiviral signaling pathways. It is unknown whether cellular infection by MERS-CoV activates the stress response pathway or whether the virus has evolved strategies to suppress this infection-limiting pathway. Here, we show that cellular infection with MERS-CoV does not lead to the formation of SGs. By transiently expressing the MERS-CoV accessory proteins individually, we identified a role of protein 4a (p4a) in preventing activation of the stress response pathway. Expression of MERS-CoV p4a impeded dsRNA-mediated PKR activation, thereby rescuing translation inhibition and preventing SG formation. In contrast, p4a failed to suppress stress response pathway activation that is independent of PKR and dsRNA. MERS-CoV p4a is a dsRNA binding protein. Mutation of the dsRNA binding motif in p4a disrupted its PKR antagonistic activity. By inserting p4a in a picornavirus lacking its natural PKR antagonist, we showed that p4a exerts PKR antagonistic activity also under infection conditions. However, a recombinant MERS-CoV deficient in p4a expression still suppressed SG formation, indicating the expression of at least one other stress response antagonist. This virus also suppressed the dsRNA-independent stress response pathway. Thus, MERS-CoV interferes with antiviral stress responses using at least two different mechanisms, with p4a

  14. Epidemiologic Parameters of the Middle East Respiratory Syndrome Outbreak in Korea, 2015

    PubMed Central

    Yoo, Jin-Hong; Choi, Jung-Hyun

    2016-01-01

    Background Epidemiologic parameters are important in planning infection control policies during the outbreak of emerging infections. Korea experienced an outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) infection in 2015, which was characterized by superspreading events in healthcare settings. We aimed to estimate the epidemiologic parameters over time during the outbreak to assess the effectiveness of countermeasures. Materials and Methods Publicly available data pertaining to the MERS outbreak in Korea were collected. We estimated the incubation periods of 162 cases whose sources of exposure were identified and the temporal trend was evaluated. Factors influencing incubation duration were analyzed. The generational reproduction number (Rg) and case reproduction number (Rc) were estimated over time. Results The estimated median incubation period was 7.4 days (95% CI, 6.9-8.0). Median incubation periods tended to be longer over time as the disease generation progressed: 6.16 days (95% CI, 5.38-6.97), 7.68 days (95% CI, 7.04-8.44), and 7.95 days (95% CI, 6.25-9.88) in the first, second, and third generations, respectively. The number of days of illness in the source cases at the time of exposure inversely correlated with the incubation periods in the receiving cases (HR 0.91 [95% CI, 0.84-0.99] per one illness day increase; P=0.026). This relationship was consistent (HR 0.83 [95% CI, 0.74-0.93] per one illness day increase) in the multivariable analysis incorporating clinical characteristics, the order of generation, and a link to superspreaders. Because the third generation cases were exposed to their source cases in the early stage (median one day) compared to the second generation cases (median 6 days), the temporal trend of incubation periods appears to be influenced by early isolation of symptomatic cases and reduction of potential exposure to source cases in the later stage. Rg declined rapidly from 28 to 0.23 in two generations. Rc dropped

  15. LLNL Middle East and North Africa and Former Soviet Union Research Database

    SciTech Connect

    O'Boyle, J.L.; Ruppert, S.D.; Hauk, T.F.; Dodge, D.; Firpo, M.

    2000-07-14

    The Lawrence Livermore National Laboratory (LLNL) Ground-Based Nuclear Explosion Monitoring (GNEM) R and D program has made significant progress populating a comprehensive Seismic Research knowledge Base (SRKB) and deriving calibration parameters for the Middle East and North Africa (ME/NA) and Former Soviet Union (FSU) regions. The LLNL SRKB provides not only a coherent framework in which to store and organize very large volumes of collected seismic waveforms, associated event parameter information, and spatial contextual data, but also provides an efficient data processing/research environment for deriving location and discrimination correction surfaces. The SRKB is a flexible and extensible framework consisting of a relational database (RDB), Geographical Information System (GIS), and associated product/data visualization and data management tools. This SRKB framework is designed to accommodate large volumes of data (over 2 million waveforms from 20,000 events) in diverse formats from many sources in addition to maintaining detailed quality control and metadata. Using the SRKB framework, they are combining travel-time observations, event characterization studies, and regional tectonic models to assemble a library of ground truth information and phenomenology correction surfaces required for support of the ME/NA and FSU regionalization program. Corrections and parameters distilled from the LLNL SRKB provide needed contributions to the DOE Knowledge Base (DOE KB) for the ME/NA and FSU regions and will help improve monitoring for underground nuclear testing. The LLNL research products will facilitate calibration of IMS stations (primary and auxiliary), their surrogates (if not yet installed) and selected gamma stations necessary to complete the above tasks in the ME/NA and FSU regions. They present expanded lookup tables for critical station parameter information (including location and response) and a new integrated and reconciled event catalog dataset including

  16. Spatial and Temporal Epidemiology of Lumpy Skin Disease in the Middle East, 2012–2015

    PubMed Central

    Alkhamis, Mohammad A.; VanderWaal, Kimberly

    2016-01-01

    Lumpy skin disease virus (LSDV) is an infectious disease of cattle that can have severe economic implications. New LSD outbreaks are currently circulating in the Middle East (ME). Since 2012, severe outbreaks were reported in cattle across the region. Characterizing the spatial and temporal dynamics of LSDV in cattle populations is prerequisite for guiding successful surveillance and control efforts at a regional level in the ME. Here, we aim to model the ecological niche of LSDV and identify epidemic progression patterns over the course of the epidemic. We analyzed publically available outbreak data from the ME for the period 2012–2015 using presence-only maximum entropy ecological niche modeling and the time-dependent method for the estimation of the effective reproductive number (R-TD). High-risk areas (probability >0.60) for LSDV identified by ecological niche modeling included parts of many northeastern ME countries, though Israel and Turkey were estimated to be the most suitable locations for occurrence of LSDV outbreaks. The most important environmental predictors that contributed to the ecological niche of LSDV included annual precipitation, land cover, mean diurnal range, type of livestock production system, and global livestock densities. Average monthly effective R-TD was equal to 2.2 (95% CI: 1.2, 3.5), whereas the largest R-TD was estimated in Israel (R-TD = 22.2, 95 CI: 15.2, 31.5) in September 2013, which indicated that the demographic and environmental conditions during this period were suitable to LSDV super-spreading events. The sharp drop of Isreal’s inferred R-TD in the following month reflected the success of their 2013 vaccination campaign in controlling the disease. Our results identified areas in which underreporting of LSDV outbreaks may have occurred. More epidemiological information related to cattle populations are needed to further improve the inferred spatial and temporal characteristics of currently circulating LSDV. However

  17. Seismic Hazard Assessment of Middle East Region: Based on the Example to Georgia (Preliminary results)

    NASA Astrophysics Data System (ADS)

    Tsereteli, N. S.; Akkar, S.; Askan, A.; Varazanashvili, O.; Adamia, S.; Chkhitunidze, M.

    2012-12-01

    The country of Georgia is located between Russia and Turkey. The main morphological units of Georgia are the mountain ranges of the Greater and Lesser Caucasus separated by the Black Sea-Rioni and Kura (Mtkvari)-South Caspian intermountain troughs. Recent geodynamics of Georgia and adjacent territories of the Black Sea-Caspian Sea region, as a whole, are determined by its position between the still-converging Eurasian and Africa-Arabian plates. That caused moderate seismicity in the region. However, the risk resulting from these earthquakes is considerably high, as recent events during the last two decades have shown. Seismic hazard and risk assessment is a major research topic in various recent international and national projects. Despite the current efforts, estimation of regional seismic hazard assessment remains as a major problem. Georgia is one of the partners of ongoing regional project EMME (Earthquake Model for Middle East region). The main objective of EMME is calculation of Earthquake hazard uniformly with heights standards. One approach used in the project is the probabilistic seismic hazard assessment PSHA. In this study, we present the preliminary results of PSHA for Georgia in this project attempting to improve gaps especially in such steps as: determination of seismic sources; selection or derivation of ground motion prediction equations models; estimation of maximum magnitude Mmax. Seismic sources (SS) were obtained on the bases of structural geology, parameters of seismicity and seismotectonics. Finely new SS have been developed for Georgia and adjacent region. Each zone was defined with the following parameters: the magnitude-frequency parameters, maximum magnitude, and depth distribution as well as modern dynamical characteristics widely used for complex processes. As the ground motion dataset is absolutely insufficient by itself to derive a ground motion prediction model for Georgia, two approaches were taken in defining ground motions. First

  18. Spatial and Temporal Epidemiology of Lumpy Skin Disease in the Middle East, 2012-2015.

    PubMed

    Alkhamis, Mohammad A; VanderWaal, Kimberly

    2016-01-01

    Lumpy skin disease virus (LSDV) is an infectious disease of cattle that can have severe economic implications. New LSD outbreaks are currently circulating in the Middle East (ME). Since 2012, severe outbreaks were reported in cattle across the region. Characterizing the spatial and temporal dynamics of LSDV in cattle populations is prerequisite for guiding successful surveillance and control efforts at a regional level in the ME. Here, we aim to model the ecological niche of LSDV and identify epidemic progression patterns over the course of the epidemic. We analyzed publically available outbreak data from the ME for the period 2012-2015 using presence-only maximum entropy ecological niche modeling and the time-dependent method for the estimation of the effective reproductive number (R-TD). High-risk areas (probability >0.60) for LSDV identified by ecological niche modeling included parts of many northeastern ME countries, though Israel and Turkey were estimated to be the most suitable locations for occurrence of LSDV outbreaks. The most important environmental predictors that contributed to the ecological niche of LSDV included annual precipitation, land cover, mean diurnal range, type of livestock production system, and global livestock densities. Average monthly effective R-TD was equal to 2.2 (95% CI: 1.2, 3.5), whereas the largest R-TD was estimated in Israel (R-TD = 22.2, 95 CI: 15.2, 31.5) in September 2013, which indicated that the demographic and environmental conditions during this period were suitable to LSDV super-spreading events. The sharp drop of Isreal's inferred R-TD in the following month reflected the success of their 2013 vaccination campaign in controlling the disease. Our results identified areas in which underreporting of LSDV outbreaks may have occurred. More epidemiological information related to cattle populations are needed to further improve the inferred spatial and temporal characteristics of currently circulating LSDV. However, the

  19. Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro)

    PubMed Central

    Tomar, Sakshi; Johnston, Melanie L.; St. John, Sarah E.; Osswald, Heather L.; Nyalapatla, Prasanth R.; Paul, Lake N.; Ghosh, Arun K.; Denison, Mark R.; Mesecar, Andrew D.

    2015-01-01

    All coronaviruses, including the recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) from the β-CoV subgroup, require the proteolytic activity of the nsp5 protease (also known as 3C-like protease, 3CLpro) during virus replication, making it a high value target for the development of anti-coronavirus therapeutics. Kinetic studies indicate that in contrast to 3CLpro from other β-CoV 2c members, including HKU4 and HKU5, MERS-CoV 3CLpro is less efficient at processing a peptide substrate due to MERS-CoV 3CLpro being a weakly associated dimer. Conversely, HKU4, HKU5, and SARS-CoV 3CLpro enzymes are tightly associated dimers. Analytical ultracentrifugation studies support that MERS-CoV 3CLpro is a weakly associated dimer (Kd ∼52 μm) with a slow off-rate. Peptidomimetic inhibitors of MERS-CoV 3CLpro were synthesized and utilized in analytical ultracentrifugation experiments and demonstrate that MERS-CoV 3CLpro undergoes significant ligand-induced dimerization. Kinetic studies also revealed that designed reversible inhibitors act as activators at a low compound concentration as a result of induced dimerization. Primary sequence comparisons and x-ray structural analyses of two MERS-CoV 3CLpro and inhibitor complexes, determined to 1.6 Å, reveal remarkable structural similarity of the dimer interface with 3CLpro from HKU4-CoV and HKU5-CoV. Despite this structural similarity, substantial differences in the dimerization ability suggest that long range interactions by the nonconserved amino acids distant from the dimer interface may control MERS-CoV 3CLpro dimerization. Activation of MERS-CoV 3CLpro through ligand-induced dimerization appears to be unique within the genogroup 2c and may potentially increase the complexity in the development of MERS-CoV 3CLpro inhibitors as antiviral agents. PMID:26055715

  20. An inventory survey at the site of the proposed Kilauea Middle East Rift Zone (KMERZ), Well Site No. 2

    SciTech Connect

    Kennedy, Joseph

    1991-03-01

    At the request of True Mid Pacific Geothermal, Archaeological Consultants of Hawaii, Inc. has conducted an inventory survey at the site of the proposed Kilauea Middle East Rift Zone (KMERZ), Well Site No.2, TMK: 1-2-10:3. The Principal Investigator was Joseph Kennedy M.A., assisted by Jacob Kaio, Field Supervisor and field crew Mark Borrello B.A., Michael O'Shaughnessy B.A., and Randy Adric. This report supercedes all previous reports submitted to the Historic Presentation Section of the Department of Land and Natural Resources. In addition to 100% surface coverage of the 400 x 400 foot well pad itself, 100% surface coverage of a substantial buffer zone was also completed. This buffer zone was established by the Department of Land and Natural Resources, Historic Preservation personnel and extends 1000 feet east and west of the well site and 500 feet north and south of the well site.