Science.gov

Sample records for migration project progress

  1. Laboratory and field studies related to the radionuclide migration project. Progress report, October 1, 1980-September 30, 1981

    SciTech Connect

    Daniels, W.R.

    1982-02-01

    FY 1981 laboratory and field studies related to the Radionuclide Migration project are described. Results are presented for radiochemical analyses of water samples collected from the RNM-1 well and the RNM-2S satellite well at the Cambric site. Data are included for tritium, {sup 85}Kr, {sup 129}I, and {sup 36}Cl. The maximum-concentration tritium, peak appears to have arrived at RNM-2S near the end of FY-1981. Laboratory studies emphasize the sorptive behavior of alluvium and tuff and its dependence on mineralogy. Results from batch measurements and crushed-rock and whole-core column studies are presented.

  2. Probabilistic population projections with migration uncertainty.

    PubMed

    Azose, Jonathan J; Ševčíková, Hana; Raftery, Adrian E

    2016-06-07

    We produce probabilistic projections of population for all countries based on probabilistic projections of fertility, mortality, and migration. We compare our projections to those from the United Nations' Probabilistic Population Projections, which uses similar methods for fertility and mortality but deterministic migration projections. We find that uncertainty in migration projection is a substantial contributor to uncertainty in population projections for many countries. Prediction intervals for the populations of Northern America and Europe are over 70% wider, whereas prediction intervals for the populations of Africa, Asia, and the world as a whole are nearly unchanged. Out-of-sample validation shows that the model is reasonably well calibrated.

  3. Bayesian Probabilistic Projection of International Migration.

    PubMed

    Azose, Jonathan J; Raftery, Adrian E

    2015-10-01

    We propose a method for obtaining joint probabilistic projections of migration for all countries, broken down by age and sex. Joint trajectories for all countries are constrained to satisfy the requirement of zero global net migration. We evaluate our model using out-of-sample validation and compare point projections to the projected migration rates from a persistence model similar to the method used in the United Nations' World Population Prospects, and also to a state-of-the-art gravity model.

  4. HARVARD PROJECT PHYSICS PROGRESS REPORT.

    ERIC Educational Resources Information Center

    Harvard Univ., Cambridge, MA.

    THIS REPORT OF HARVARD PROJECT PHYSICS PRESENTS DRAFTS OF THREE SPEECHES DELIVERED TO THE AMERICAN ASSOCIATION OF PHYSICS TEACHERS (AAPT) MEETING, FEBRUARY, 1967. THE ADDRESS BY GERALD HOLTON DEALS WITH THE AIMS AND PROGRESS OF THE PROJECT. DISCUSSED ARE (1) PROJECT PARTICIPANTS, (2) AIMS AND CONTENT, (3) THE NEW EMPHASIS, (4) SURVEY OF COURSE…

  5. Migrating Professional Knowledge: Progressions, Regressions, and Dislocations

    ERIC Educational Resources Information Center

    Slade, Bonnie L.

    2015-01-01

    Drawing on practice-based learning theory, this chapter examines issues pertaining to the deskilling of immigrant professionals in Canada. It argues that adult educators need to have an awareness of transnational migration dynamics and work in meaningful ways to keep immigrant professionals connected to professional knowledge practices.

  6. CERN ELENA project progress report

    NASA Astrophysics Data System (ADS)

    Bartmann, Wolfgang; Belochitskii, Pavel; Breuker, Horst; Butin, François; Carli, C.; Eriksson, Tommy; Oelert, Walter; Maury, Stephan; Pasinelli, Sergio; Tranquille, Gerard

    2015-05-01

    The Extra Low Energy Antiproton ring (ELENA) is a CERN project aiming at constructing a 30 m circumference synchrotron to further decelerate antiprotons from the Antiproton Decelerator (AD) from 5.3 MeV to 100 keV. The additional deceleration complemented by an electron cooler to reduce emittances will allow the existing AD experiments to increase substantially their antiproton capture efficiencies and render new experiments possible. The ELENA design is now well advanced and the project has entered the construction stage, in particular for what concerns the infrastructure. Installation of the machine components is foreseen during the second half of 2015 and beginning of 2016 followed by ring commissioning until the end of 2016. New electrostatic transfer lines to the experiments will be installed and commissioned during the first half of 2017 followed by the first physics operation with AD/ELENA end of 2017. Main ELENA related infrastructure progresses as well as the status of the project are reported.

  7. TAFE Projects in Progress. No. 1.

    ERIC Educational Resources Information Center

    Skott, Diana, Comp.

    1982-01-01

    This publication contains a listing of educational research and development projects currently in progress in Australia, which is the first of a planned twice-yearly listing of projects in progress. Projects are listed by territories and are indexed by author and by subject. Information supplied for each project includes a reference number,…

  8. Progress on the DPASS project

    NASA Astrophysics Data System (ADS)

    Galkin, Sergei A.; Bogatu, I. N.; Svidzinski, V. A.

    2015-11-01

    A novel project to develop Disruption Prediction And Simulation Suite (DPASS) of comprehensive computational tools to predict, model, and analyze disruption events in tokamaks has been recently started at FAR-TECH Inc. DPASS will eventually address the following aspects of the disruption problem: MHD, plasma edge dynamics, plasma-wall interaction, generation and losses of runaway electrons. DPASS uses the 3-D Disruption Simulation Code (DSC-3D) as a core tool and will have a modular structure. DSC is a one fluid non-linear, time-dependent 3D MHD code to simulate dynamics of tokamak plasma surrounded by pure vacuum B-field in the real geometry of a conducting tokamak vessel. DSC utilizes the adaptive meshless technique with adaptation to the moving plasma boundary, with accurate magnetic flux conservation and resolution of the plasma surface current. DSC has also an option to neglect the plasma inertia to eliminate fast magnetosonic scale. This option can be turned on/off as needed. During Phase I of the project, two modules will be developed: the computational module for modeling the massive gas injection and main plasma respond; and the module for nanoparticle plasma jet injection as an innovative disruption mitigation scheme. We will report on this development progress. Work is supported by the US DOE SBIR grant # DE-SC0013727.

  9. Minneapolis Multi-Ethnic Curriculum Project--Migration Unit.

    ERIC Educational Resources Information Center

    Minneapolis Public Schools, Minn. Dept. of Intergroup Education.

    The student booklet presents short chapters illustrating the migration unit of the Minneapolis Multi-Ethnic Curriculum Project for secondary schools. Sixteen brief chapters describe migration, immigration, and emigration in the United States. The first six chapters offer first person accounts of immigrants from Norway, Korea, Egypt, Hitler's…

  10. Progress Update: Stack Project Complete

    ScienceCinema

    Cody, Tom

    2016-07-12

    Progress update from the Savannah River Site. The 75 foot 293 F Stack, built for plutonium production, was cut down to size in order to prevent injury or release of toxic material if the structure were to collapse due to harsh weather.

  11. Progress Update: Stack Project Complete

    SciTech Connect

    Cody, Tom

    2010-01-01

    Progress update from the Savannah River Site. The 75 foot 293 F Stack, built for plutonium production, was cut down to size in order to prevent injury or release of toxic material if the structure were to collapse due to harsh weather.

  12. The International Project. Progress Report.

    ERIC Educational Resources Information Center

    Rutimann, Hans

    The International Project of the Commission on Preservation and Access was begun in June 1988 to explore the feasibility of creating an international database of preserved materials. Its main goals are to: (1) determine the extent to which preservation records exist in other countries; (2) identify the difficulties in converting records to…

  13. Project MEDICO Third Progress Report.

    ERIC Educational Resources Information Center

    Artandi, Susan; Baxendale, Stanley

    This report describes the searching methods and the search program for the automatic indexing method which was developed and implemented in an earlie r phase of the project. The indexing method generates index tags automatically from English language text and creates a machine searchable file of index records for the document being processed.…

  14. International megaregional project-principles and progress

    SciTech Connect

    Bertagne, A.J. )

    1993-02-01

    The International Megaregional Project is a worldwide project involving the compilation and interpretation of long regional seismic lines crossing international basins. The goal of the project is to synthesize the current geologic knowledge of the areas traversed and to identify new areas of exploration interest. The project is modeled after, and an extension of the well-documented U.S. Megaregional Project (see AAPG Explorer, September 1990, Oil and Gas Journal, November 4, 1991). A conceptual international Megaregional framework has been established and will serve as a focus for the geologic efforts and seismic data compilation. The work is being conducted with the cooperation of a consortium of multinational oil companies as well as host governments. Megaregional lines can provide new insights into: (1) what is and is not basement, (2) maturation history and migration pathways, (3) regional structure, and (4) regional stratigraphy. The lines can thereby lead to the development of new exploration concepts. The paper will include examples of completed Magaregional lines and will provide an update on the status of the project, with an emphasis on Latin America.

  15. Eggen Card Project: Progress and Plans (Abstract)

    NASA Astrophysics Data System (ADS)

    Silvis, G.

    2016-12-01

    (Abstract only) The Eggen Card Project has been running since 2009 and has involved 30+ AAVSO staff and volunteers. Let me offer a short review of the project, our progress this year and our plans for the future. Phase 1 of the project has been to index the 108,000 card images, identifying the stars they belong too. We've passed the 75% point on this phase. The next phase is how to use this data. Jack Crast has identified the photometric schemes used by Olin and developed a spreadsheet tool to prepare this data for inclusion into the AAVSO International Database (AID). Anyone want good photometry from 1970? We got it!

  16. Tevatron beam-beam compensation project progress

    SciTech Connect

    Shiltsev, V.; Zhang, X.L.; Kuznetsov, G.; Pfeffer, H.; Saewert, G.; Zimmermann, F.; Tiunov, M.; Bishofberger, K.; Bogdanov, I.; Kashtanov, E.; Kozub, S.; Sytnik, V.; Tkachenko, L.; /Serpukhov, IHEP

    2005-05-01

    In this paper, we report the progress of the Tevatron Beam-Beam Compensation (BBC) project [1]. Electron beam induced proton and antiproton tuneshifts have been reported in [2], suppression of an antiproton emittance growth has been observed, too [1]. Currently, the first electron lens (TEL1) is in operational use as the Tevatron DC beam cleaner. We have made a lot of the upgrades to improve its stability [3]. The 2nd Tevatron electron lens (TEL2) is under the final phase of development and preparation for installation in the Tevatron.

  17. Hydrology and radionuclide migration program 1987 progress report

    SciTech Connect

    Marsh, K.V.

    1991-03-01

    This report presents results from the Lawrence Livermore National Laboratory's participation in the Hydrology and Radionuclide Migration Program at the Nevada Test Site (NTS) during the fiscal year 1987. The report discussed initial data from a new well (UE20n-1) drilled at the Cheshire site; presents a description of a proposed laboratory study of migration of colloids in fractured media; lists data collected during the drilling and initial sampling of UE20n-1; and describes a tentative proposal for work to be performed in FY88 by Lamont-Doherty Geological Observatory. Groundwater sampled from the new well at the Cheshire site contains tritium concentrations comparable to those measured in previous years from locations above and within the Cheshire cavity. This presence of tritium, as well as several other radionuclides, in a well 100 m away from the cavity region indicates transport of radionuclides, validates a proposed model of the flow path, and provides data on rates of groundwater flow. Previous work at the Cheshire site has shown that radionuclides are transported by colloids through fractured media. However, we have no data that can be used for predictive modeling, and existing theories are not applicable. While physical transport mechanisms of sub-micrometer colloids to defined mineral surfaces are well known, predictions based on well-defined conditions differ from experimental observations by orders of magnitude. The U.C. Berkeley group has designed a laboratory experiment to quantify colloid retention and permeability alteration by the retained colloids.

  18. Landbird migration in the American West: Recent progress and future research directions

    USGS Publications Warehouse

    Carlisle, J.D.; Skagen, S.K.; Kus, B.E.; van Riper, Charles; Paxton, K.L.; Kelly, J.F.

    2009-01-01

    Our knowledge of avian behaviors during the nonbreeding period still lags behind that of the breeding season, but the last decade has witnessed a proliferation in research that has yielded significant progress in understanding migration patterns of North American birds. And, although historically the great majority of migration research has been conducted in the eastern half of the continent, there has been much recent progress on aspects of avian migration in the West. In particular, expanded use of techniques such as radar, plasma metabolites, mist-netting, count surveys, stable isotopes, genetic data, and animal tracking, coupled with an increase in multi-investigator collaborations, have all contributed to this growth of knowledge. There is increasing recognition that migration is likely the most limiting time of year for migratory birds, increasing the importance of continuing to decipher patterns of stopover ecology, identifying critical stopover habitats, and documenting migration routes in the diverse and changing landscapes of the American West. Here, we review and briefly synthesize the latest findings and advances in avian migration and consider research needs to guide future research on migration in the West. ?? 2009 by The Cooper Ornithological Society. All rights reserved.

  19. The Astronomy Genealogy Project: A Progress Report

    NASA Astrophysics Data System (ADS)

    Tenn, Joseph S.

    2016-01-01

    Although it is not yet visible, much progress has been made on the Astronomy Genealogy Project (AstroGen) since it was accepted as a project of the Historical Astronomy Division (HAD) three years ago. AstroGen will list the world's astronomers with information about their highest degrees and advisors. (In academic genealogy, your thesis advisor is your parent.) A small group (the AstroGen Team) has compiled a database of approximately 12,000 individuals who have earned doctorates with theses (dissertations) on topics in astronomy, astrophysics, cosmology, or planetary science. These include nearly all those submitted in Australia, Canada, the Netherlands, and New Zealand, and most of those in the United States (all through 2014 for most universities and all through 1990 for all). We are compiling more information than is maintained by the Mathematics Genealogy Project (MGP). In addition to name, degree, university, year of degree, and thesis advisor(s), all provided by MGP as well, we are including years of birth and death when available, mentors in addition to advisors, and links to the thesis when it is online and to the person's web page or obituary, when we can find it. We are still struggling with some questions, such as the boundaries of inclusion and whether or not to include subfields of astronomy. We believe that AstroGen will be a valuable resource for historians of science as well as a source of entertainment for those who like to look up their academic family trees. A dedicated researcher following links from AstroGen will be able to learn quite a lot about the careers of astronomy graduates of a particular university, country, or era. We are still seeking volunteers to enter the graduates of one or more universities.

  20. The PLX- α Project: Progress and Plans

    NASA Astrophysics Data System (ADS)

    Hsu, S.; Witherspoon, F. D.; Cassibry, J.; Gilmore, M.; Samulyak, R.; Stoltz, P.; PLX-α Team

    2016-10-01

    The Plasma Liner Experiment-ALPHA (PLX- α) project aims to demonstrate the viability of spherically imploding plasma liners as a standoff driver for plasma-jet-driven magneto-inertial fusion (PJMIF). In the past year, progress has been made in designing and testing new contoured-gap coaxial guns, 3D model development and simulations (via Eulerian and Lagrangian hydrocodes) of PLX- α-relevant plasma-liner formation/implosion via up to 60 plasma jets ( 100 kJ of liner kinetic energy), 1D semi-analytic and numerical modeling of reactor-scale PJMIF (10s of MJ of liner kinetic energy), and preparation/upgrade of the PLX facility/diagnostics. The design goal for the coaxial guns is to form plasma jets of up to initial n 2 ×1016 cm-3, mass 5 mg, Vjet 50 km/s, rjet = 4 cm, and length 10 cm. The modeling research is assessing ram-pressure amplification and Mach-number degradation during liner convergence, evolution of liner non-uniformity amplitude and mode number, and exploration of PJMIF configurations with promising 1D and 2D fusion gains. Conical multi-jet-merging and full-4 π experiments will commence in Fall, 2016 and late 2017, respectively. Supported by the ARPA-E ALPHA Program.

  1. Progress of the Sarlux IGCC project

    SciTech Connect

    Collodi, G.; Zaccolo, G.

    1998-07-01

    SARLUX, a joint venture between SARAS and ENRON, is developing a new 551 MW IGCC plant in the SARAS Refinery located in Sarroch, Sardinia, Italy. The plant will be built by the Raggruppamento Temporaneo d'Imprese (Consortium) formed by SNAMPROGETTI - GENERAL ELECTRIC - TURBOTECNICA under a lump-sum, turn-key construction contract. The process configuration includes three parallel Texaco low pressure quench gasifiers (TAR feedstock) followed by two trains of gas cooling, COS hydrolysis, Selexol (UOP) sulphur removal and syngas moisturization. The combined cycle unit (CCU) consists of three parallel single shaft units General Electric STAG 109E producing 551 MW net power to ENEL national grid. Facilities for pure hydrogen and liquid sulphur production are included, as well as all necessary utilities required to support the IGCC operation. The contract, started on January 1997, is at present under the construction phase. After 14 months, the overall progress of the project is 47% with the engineering and procurement activities almost concluded. The commissioning of the utility units is expected from September 1998, the first CCU train on March 1999 (on gasoil) and the first gasifier will be ignited on August 1999. At present an intensive and complete training program is under-way for the Sarlux personnel involved in the management and conduction of the new IGCC.

  2. Fluor Hanford Project Focused Progress at Hanford

    SciTech Connect

    HANSON, R.D.

    2000-02-01

    Fluor Hanford is making significant progress in accelerating cleanup at the Hanford site. This progress consistently aligns with a new strategic vision established by the U.S. Department of Energy's Richland Operations Office (RL).

  3. Introduction and Progress of APOSOS Project

    NASA Astrophysics Data System (ADS)

    Zhao, You; Gao, P. Q.; Shen, Ming; Chaudhry, Maqbool A.; Guo, Xiaozhong; Teng, D. P.; Yang, Datao; Yu, Huanhuan; Zhao, Zhe

    Asia-Pacific Ground-Based Optical Satellite Observation System (APOSOS) project is based on members of Asia-Pacific Space Cooperation Organization (APSCO). Its aim is to develop a regional or even global satellite tracking network basically composed of optical trackers. The system will be used to track objects of interest or space-debris for the safety of spacecraft launch mission or the intactness of operational satellites. The system will benefit from the distribution of APSCO members and multi-national fund support or technical cooperation. Thus APOSOS will have a potential capability to observe all the satellites orbiting earth with high precision but relatively low cost. This paper will present the introduction, progress and current status of APOSOS project, including: System Requirements Definition, System Main Mission, System Goal, System design, Services and Clients, Organization Framework of Observation Center, Major Function of Observation Center, Establishment of Observation Plan, Format Standard for Exchanging Data, Data Policy, Implementation Schedule, etc.. APOSOS will build a unified surveillance network from observational facilities of member states involved, to utilize the wide geographical distribution advantage of multi-country. It will be operated under the coordination of APSCO observation mission management department. (1)APOSOS should conduct observation missions of specific satellites, space-debris or other space objects of interest, based on requirements of member states. APOSOS should fulfill the basic requirement for satellites observation and tracking missions. And it should also have the potential ability of small debris detection to support collision avoidance planning, which can protect the members high valued space assets. (2)In some particular application, APOSOS would be able to be used for long-term tracking of specific space object of interest, and have the ability of data processing and analysis, so as to provide conjunction

  4. Progress in direct heat applications projects

    SciTech Connect

    Childs, F.W.; Jones, K.W.; Nelson, L.B.; Strawn, J.A.; Tucker, M.K.

    1980-09-09

    The development of hydrothermal energy for direct heat applications is being aided by twenty-two demonstration projects that are funded on a cost-sharing basis by the US Department of Energy, Division of Geothermal Energy. These projects are designed to demonstrate the technical and economic feasibility of the direct use of geothermal heat in the United States. Twelve of these projects are administered by the DOE-Idaho Operations Office with technical support from EG and G Idaho, Inc. Engineering and economic data for these projects are summarized in this paper. The data and experience being generated by these projects will be an important basis for future geothermal direct use projects.

  5. 7 CFR 3406.26 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... project and grant management, opportunities for collaborative efforts, future directions for education reform, research project management, advancing a field of science, and opportunities to enhance... 7 Agriculture 15 2014-01-01 2014-01-01 false Monitoring progress of funded projects....

  6. 7 CFR 3406.26 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... project and grant management, opportunities for collaborative efforts, future directions for education reform, research project management, advancing a field of science, and opportunities to enhance... 7 Agriculture 15 2013-01-01 2013-01-01 false Monitoring progress of funded projects....

  7. 7 CFR 3406.26 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... project and grant management, opportunities for collaborative efforts, future directions for education reform, research project management, advancing a field of science, and opportunities to enhance... 7 Agriculture 15 2011-01-01 2011-01-01 false Monitoring progress of funded projects....

  8. 7 CFR 3406.26 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... purpose of the meeting will be to discuss project and grant management, opportunities for collaborative efforts, future directions for education reform, research project management, advancing a field of science... 7 Agriculture 15 2010-01-01 2010-01-01 false Monitoring progress of funded projects....

  9. 7 CFR 3406.26 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... project and grant management, opportunities for collaborative efforts, future directions for education reform, research project management, advancing a field of science, and opportunities to enhance... 7 Agriculture 15 2012-01-01 2012-01-01 false Monitoring progress of funded projects....

  10. Repeat migration and remittances as mechanisms for wealth inequality in 119 communities from the Mexican Migration Project data.

    PubMed

    Garip, Filiz

    2012-11-01

    To evaluate the distributional impact of remittances in origin communities, prior research studied how migrants' selectivity by wealth varies with migration prevalence in the community or prior migration experience of the individual. This study considers both patterns; it examines selectivity separately in low- and high-prevalence communities and for first-time and repeat migrants. Based on data from 18,042 household heads in 119 Mexican communities from the Mexican Migration Project, the analyses show that (1) first-time migrants in low-prevalence communities come from poor households, whereas repeat migrants in high-prevalence communities belong to wealthy households; and (2) higher amounts of remittances reach wealthy households. These results suggest that repeat migration and remittances may be mechanisms for wealth accumulation in the study communities. Descriptive analyses associate these mechanisms with increasing wealth disparities between households with and without migrants, especially in high-prevalence communities. The study, similar to prior findings, shows the importance of repeat migration trips, which, given sustained remittances, may amplify the wealth gap between migrants and nonmigrants in migrant-sending communities. The study also qualifies prior findings by differentiating between low- and high-prevalence communities and observing a growing wealth gap only in the latter.

  11. DOE Robotics Project. Summary of progress for 1991

    SciTech Connect

    Not Available

    1991-01-01

    This document provide the bimonthly progress reports on the Department of Energy (DOE) Robotics Project by the University of Michigan. Reports are provided for the time periods of December 90/January 91 through June 91/July 91. (FI)

  12. 7 CFR 3405.19 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS... Annual Performance Reports should include a summary of the overall progress toward project objectives... reform, and opportunities to enhance dissemination of exemplary end products/results. (b) An...

  13. 105. View of tracking radome replacement project, progress photograph, official ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    105. View of tracking radome replacement project, progress photograph, official photograph BMEWS Project by unknown photographer, 11 August 1981, clear as negative no. A-18562. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

  14. The ciliary GTPase Arl13b regulates cell migration and cell cycle progression

    PubMed Central

    Pruski, Michal; Rajnicek, Ann; Yang, Zhifu; Clancy, Hannah; Ding, Yu-Qiang; McCaig, Colin D.; Lang, Bing

    2016-01-01

    ABSTRACT The GTPase ARL13B is localized to primary cilia; small cellular protrusions that act as antennae. Its defective ARL13B hennin (HNN) variant is linked causally with Joubert Syndrome, a developmental ciliopathy attributed to poor sensing of extracellular chemical gradients. We tested the hypothesis that impaired detection of extracellular voltage gradients also contributes to the HNN phenotype. In vitro, extracellular electric fields stimulated migration of wild type (WT) and HNN fibroblasts toward the cathode but the field only increased the migration speed of WT cells. Cilia on WT cells did not align to the field vector. HNN cells divided more slowly than WT cells, arresting at the G2/M phase. Mechanistically, HNN cells had reduced phospho-ERK1/2 signaling and elevated levels of Suppressor of Fused protein. These suggest that cells may not be able to read extracellular chemical cues appropriately, resulting in deficits in cell migration and proliferation. Finally, an increase in tubulin stabilization (more detyrosinated tubulin) confirmed the general stagnation of HNN cells, which may further contribute to slower migration and cell cycle progression. We conclude that Arl13b dysfunction resulted in HNN cell stagnation due to poor growth factor signaling and impaired detection of extracellular electrical gradients, and that the role of Arl13b in cell proliferation may be understated. PMID:26963749

  15. Biorefinery Demonstration Project Final Progress Report

    SciTech Connect

    Lee, David

    2015-10-20

    In this project we focused on various aspects of biorefinery technology development including algal-biorefinery technology, thermochemical conversion of biomass to bio-oils and biochar; we tested characteristics and applications of biochars and evaluated nutrient cycling with wastewater treatment by the coupling of algal culture systems and anaerobic digestion. Key results include a method for reducing water content of bio-oil through atomized alcohol addition. The effect included increasing the pH and reducing the viscosity and cloud point of the bio-oil. Low input biochar production systems were evaluated via literature reviews and direct experimental work. Additionally, emissions were evaluated and three biochar systems were compared via a life cycle analysis. Attached growth systems for both algal cultivation and algal harvesting were found to be superior to suspended growth cultures. Nutrient requirements for algal cultivation could be obtained by the recycling of anaerobic digester effluents, thus experimentally showing that these two systems could be directly coupled. Twenty-two journal articles and six intellectual property applications resulted from the cumulative work that this project contributed to programmatically.

  16. A progress report on the LXCat project

    NASA Astrophysics Data System (ADS)

    Pancheshnyi, Sergey; Pitchford, Leanne

    2016-09-01

    LXCat is an open-access, web-based platform (www.lxcat.net) for storing, exchanging and manipulating data for modeling the electron and ion components of low-temperature, non-equilibrium plasmas. The data types supported by LXCat are electron and ion scattering cross sections and rate coefficients, electron and ion swarm/transport parameters, ion-neutral interaction potentials, and optical oscillator strengths. On-line tools allow for searching, graphical display, and downloading of data, and an on-line Boltzmann solver allows users to calculate electron transport and rate coefficients in arbitrary gas mixtures if ``complete'' sets of cross sections for the individual components are available in the databases. At present, 24 public databases contributed by different groups around the world can be accessed on LXCat. The database contributors retain ownership and are responsible for the contents and maintenance of the individual databases. New contributors are welcome and can request an account and receive instructions for setting up a password-protected database on LXCat. This presentation will summarize the LXCat project objectives, its structure, the available databases, and the current status of the project. Presented on behalf of the LXCat Team.

  17. Changes in Gas Bubble Disease Signs for Migrating Juvenile Salmonids Experimentally Exposed to Supersaturated Gasses, 1996-1997 Progress Report.

    SciTech Connect

    Absolon, Randall F.

    1999-03-01

    This study was designed to answer the question of whether gas bubble disease (GBD) signs change as a result of the hydrostatic conditions juvenile salmonids encounter when they enter the turbine intake of hydroelectric projects during their downstream migration.

  18. Progress on Suffa Large Radiotelescope Project

    NASA Astrophysics Data System (ADS)

    Shanin, G. I.; Hojaev, A. S.

    2006-08-01

    The large-scale radio astronomy facility complex (analogous to the GBT at NRAO) is being created not far from Samarkand (Uzbekistan) on Suffa plateau at 2300 m (Trimble,2001). Originally it was designed as a basic part of the Earth-Space VLBI system (Kardashev et al,1995; URL http://www.asc.rssi.ru/suffa/) and contains the radio telescope for 0.8-60 mm band with 70m main reflector, two removable subreflectors; satellite communication station; data receiving and processing system and other necessary infrastructure. The adaptive optics principle will be used for control the surface of the main mirror consisted of 1200 trapezoid panels. The site location provides good seeing conditions for cm-mm range. Averaged annual atmospheric transmission coefficients at zenith were derived as 0.90-0.98 for 3.1 mm and 5.8 mm wavelengths and about 0.60 for 1.36 (Hojaev & Shanin, 1996). The project started as far back as the period of the Soviet Union was stalled since its disintegration. Quite recently the firm decision on completing the project has been endorsed by our Governments, and Russia will invest for these; therefore the project's layouts have been considerably modernizated and updated in order to build up the state-of-art instrument. It should be operational in 2009. Now we are arranging the scientific consortium to further explore the Suffa site more deep and to learn the main 'radio astro climate' parameters by means of a new technology ('radioseeing', radio transparency in different submm, mm and cm bands, PWV , their intercorrelation and correlation with meteoparameters) for the atmosphere modelling at the site and try to forecast the "radio-weather" for reliably planning the scientific schedule of the future telescope. References: Kardashev N.S., Andreyanov V.V., Gvamichava A.S., Likhachev S.F., and Slysh V.I., 1995, , Acta Astronautica, vol.37, p.271 Hojaev A.S., Shanin G.I., 1996, JKAS, v.29 , p.S411 Trimble, V., 2001, A Year of Discovery: Astronomy Highlights of

  19. Progress on Suffa Large Radiotelescope Project

    NASA Astrophysics Data System (ADS)

    Shanin, G. I.; Hojaev, A. S.

    2006-08-01

    The large-scale radio astronomy facility complex (analogous to the GBT at NRAO) is being created not far from Samarkand (Uzbekistan) on Suffa plateau at 2300 m (Trimble,2001). Originally it was designed as a basic part of the Earth-Space VLBI system (Kardashev et al,1995; URL http://www.asc.rssi.ru/suffa/) and contains the radio telescope for 0.8-60 mm band with 70 [Author ID2: at Fri Jul 14 10:39:00 2006 ]m main reflector, two removable subreflectors; satellite communication station; data receiving and processing system and other necessary infrastructure. The adaptive optics principle will be used for control the surface of the main mirror consisted of 1200 trapezoid panels. The site location provides good seeing conditions for cm-mm range. Averaged annual atmospheric transmission coefficients at zenith were derived as 0.90-0.98 for 3.1 mm and 5.8 mm wavelengths and about 0.60 for 1.36 (Hojaev & Shanin, 1996). The project started as far back as the period of the Soviet Union was stalled since its disintegration. Quite recently the firm decision on completing the project has been endorsed by our Governments, and Russia will invest for these; therefore the project's layouts have been considerably modernizated and updated in order to build up the state-of-art instrument. It should be operational in 2009. Now we are arranging the scientific consortium to further explore the Suffa site more deep and to learn the main 'radio astro climate' parameters by means of a new technology ('radioseeing', radio transparency in different submm, mm and cm bands, PWV, their intercorrelation and correlation with meteoparameters) for the atmosphere modelling at the site and try to forecast the "radio-weather" for reliably planning the scientific schedule of the future telescope. References: Kardashev N.S., Andreyanov V.V., Gvamichava A.S., Likhachev S.F., and Slysh V.I., 1995, , Acta Astronautica, vol.37, p.271 Hojaev A.S., Shanin G.I., 1996, JKAS, v.29 , p.S411 Trimble, V., 2001, A

  20. Progress in PV:BONUS project

    NASA Astrophysics Data System (ADS)

    Spaeth, James J.; Pierce, Lizana K.

    1996-01-01

    The PV:BONUS (Building Opportunities in the U.S. for Photovoltaics) program, to develop photovoltaic products and the associated infrastructure for a sustainable photovoltaic market in the building sector, has attracted a variety of promising projects ranging from integrated modular homes, rooftop integrated photovoltaic systems, dispatchable peak shaving systems, alternating-current module, photovoltaic glazing systems, and curtain wall systems. The mutual commitment by the Department of Energy and the program recipients has inspired diverse partnerships among manufacturers, utilities, construction companies, and universities for the development of niche markets for building-integrated photovoltaics. Many of the photovoltaic systems are currently being demonstrated with market campaigns underway to commercialize these innovative renewable energy, building-integrated products.

  1. Navigator-3, a modulator of cell migration, may act as a suppressor of breast cancer progression

    PubMed Central

    Cohen-Dvashi, Hadas; Ben-Chetrit, Nir; Russell, Roslin; Carvalho, Silvia; Lauriola, Mattia; Nisani, Sophia; Mancini, Maicol; Nataraj, Nishanth; Kedmi, Merav; Roth, Lee; Köstler, Wolfgang; Zeisel, Amit; Yitzhaky, Assif; Zylberg, Jacques; Tarcic, Gabi; Eilam, Raya; Wigelman, Yoav; Will, Rainer; Lavi, Sara; Porat, Ziv; Wiemann, Stefan; Ricardo, Sara; Schmitt, Fernando; Caldas, Carlos; Yarden, Yosef

    2015-01-01

    Dissemination of primary tumor cells depends on migratory and invasive attributes. Here, we identify Navigator-3 (NAV3), a gene frequently mutated or deleted in human tumors, as a regulator of epithelial migration and invasion. Following induction by growth factors, NAV3 localizes to the plus ends of microtubules and enhances their polarized growth. Accordingly, NAV3 depletion trimmed microtubule growth, prolonged growth factor signaling, prevented apoptosis and enhanced random cell migration. Mathematical modeling suggested that NAV3-depleted cells acquire an advantage in terms of the way they explore their environment. In animal models, silencing NAV3 increased metastasis, whereas ectopic expression of the wild-type form, unlike expression of two, relatively unstable oncogenic mutants from human tumors, inhibited metastasis. Congruently, analyses of > 2,500 breast and lung cancer patients associated low NAV3 with shorter survival. We propose that NAV3 inhibits breast cancer progression by regulating microtubule dynamics, biasing directionally persistent rather than random migration, and inhibiting locomotion of initiated cells. PMID:25678558

  2. 7 CFR 3405.19 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Supplementary Information § 3405.19... director(s), the institution, and the food and agricultural sciences higher education system; and data on... 7 Agriculture 15 2012-01-01 2012-01-01 false Monitoring progress of funded projects....

  3. 7 CFR 3405.19 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Supplementary Information § 3405.19... director(s), the institution, and the food and agricultural sciences higher education system; and data on... 7 Agriculture 15 2011-01-01 2011-01-01 false Monitoring progress of funded projects....

  4. 7 CFR 3405.19 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Supplementary Information § 3405.19... director(s), the institution, and the food and agricultural sciences higher education system; and data on... 7 Agriculture 15 2013-01-01 2013-01-01 false Monitoring progress of funded projects....

  5. 7 CFR 3405.19 - Monitoring progress of funded projects.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... FOOD AND AGRICULTURE HIGHER EDUCATION CHALLENGE GRANTS PROGRAM Supplementary Information § 3405.19... director(s), the institution, and the food and agricultural sciences higher education system; and data on... 7 Agriculture 15 2014-01-01 2014-01-01 false Monitoring progress of funded projects....

  6. Integrated Library System (ILS) Challenges and Opportunities: A Survey of U.S. Academic Libraries with Migration Projects

    ERIC Educational Resources Information Center

    Wang, Zhonghong

    2009-01-01

    An online survey was sent to academic libraries and consortia with an integrated library system (ILS) migration project, based on review of press releases from major U.S. ILS vendors. This study takes a systematic approach to provide a snapshot of the academic ILS market and key factors affecting the outcome of an ILS migration project. It reveals…

  7. Progress in Aging Epidemiology in Japan: The JAGES Project

    PubMed Central

    Kondo, Katsunori

    2016-01-01

    Aging is a prominent topic in global health. The purpose of this report is to document progress in two of our research projects in Japan, which currently is the most aged society in the world. The Japan Gerontological Evaluation Study (JAGES) is one of the largest nation-wide research projects on aging, with more than 100 000 participants in 2010 and 2013. One of the notable findings is that community participation is a significant determinant of older people’s health. We have also made progress in the development of the JAGES Health Equity Assessment and Response Tools (HEART), which is a management tool for developing age-friendly cities. This progress suggests that community perspective and management of health promotion in the communities are valuable and require further research. PMID:27349200

  8. Progress in Aging Epidemiology in Japan: The JAGES Project.

    PubMed

    Kondo, Katsunori

    2016-07-05

    Aging is a prominent topic in global health. The purpose of this report is to document progress in two of our research projects in Japan, which currently is the most aged society in the world. The Japan Gerontological Evaluation Study (JAGES) is one of the largest nation-wide research projects on aging, with more than 100 000 participants in 2010 and 2013. One of the notable findings is that community participation is a significant determinant of older people's health. We have also made progress in the development of the JAGES Health Equity Assessment and Response Tools (HEART), which is a management tool for developing age-friendly cities. This progress suggests that community perspective and management of health promotion in the communities are valuable and require further research.

  9. FGF19 Contributes to Tumor Progression in Gastric Cancer by Promoting Migration and Invasion.

    PubMed

    Wang, Shuang; Zhao, Daqi; Tian, Ruihua; Shi, Hailong; Chen, Xiangming; Liu, Wenzhi; Wei, Lin

    2016-01-01

    Gastric cancer is the fourth most common type of cancer and second leading cause of cancer-related death in the world. Since patients are often diagnosed at a late stage, very few effective therapies are left in the arsenal. FGF19, as a hormone, has been reported to promote tumor growth in various types of cancer; however, its function in gastric cancer remains unknown. In the current study, we showed that FGF19 is overexpressed in gastric cancer and is associated with depth of invasion, lymph node metastasis, and TNM stage. In addition, in vitro experiments demonstrated that FGF19 is able to enhance migration and invasion abilities of gastric cancer cells. Given its great potency in gastric cancer progression, FGF19 may be an effective target of treatment for advanced gastric cancer patients.

  10. Making Progress: The Use of Multiple Progress Reports to Enhance Advertising Students' Media Plan Term Projects

    ERIC Educational Resources Information Center

    Kritz, Gary H.; Lozada, Hector R.; Long, Mary M.

    2007-01-01

    Since the AACSB mandates that students demonstrate effective oral and written communication skills, it is imperative that business professors do what is necessary to improve such skills. The authors investigate whether the use of using multiple progress reports in an Advertising class project improves the final product. The data results show that…

  11. Projects at the Western Environmental Technology Office. Quarterly technical progress report, January 1--March 31, 1995

    SciTech Connect

    1995-06-01

    This quarterly report briefly describes recent progress in eight projects. The projects are entitled Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Program; Plasma Projects; Resource Recovery Project; Spray Casting Project; and Watervliet Arsenal Project.

  12. Ceramic Technology Project semiannual progress report, October 1992--March 1993

    SciTech Connect

    Johnson, D.R.

    1993-09-01

    This project was developed to meet the ceramic technology requirements of the OTS`s automotive technology programs. Although progress has been made in developing reliable structural ceramics, further work is needed to reduce cost. The work described in this report is organized according to the following work breakdown structure project elements: Materials and processing (monolithics [Si nitride, carbide], ceramic composites, thermal and wear coatings, joining, cost effective ceramic machining), materials design methodology (contact interfaces, new concepts), data base and life prediction (structural qualification, time-dependent behavior, environmental effects, fracture mechanics, nondestructive evaluation development), and technology transfer.

  13. Macrophage/Epithelium Cross-Talk Regulates Cell Cycle Progression and Migration in Pancreatic Progenitors

    PubMed Central

    McLennan, Linsey; Gearhart, Addie; Jimenez-Caliani, Antonio J.; Cirulli, Vincenzo; Crisa, Laura

    2014-01-01

    Macrophages populate the mesenchymal compartment of all organs during embryogenesis and have been shown to support tissue organogenesis and regeneration by regulating remodeling of the extracellular microenvironment. Whether this mesenchymal component can also dictate select developmental decisions in epithelia is unknown. Here, using the embryonic pancreatic epithelium as model system, we show that macrophages drive the epithelium to execute two developmentally important choices, i.e. the exit from cell cycle and the acquisition of a migratory phenotype. We demonstrate that these developmental decisions are effectively imparted by macrophages activated toward an M2 fetal-like functional state, and involve modulation of the adhesion receptor NCAM and an uncommon “paired-less” isoform of the transcription factor PAX6 in the epithelium. Over-expression of this PAX6 variant in pancreatic epithelia controls both cell motility and cell cycle progression in a gene-dosage dependent fashion. Importantly, induction of these phenotypes in embryonic pancreatic transplants by M2 macrophages in vivo is associated with an increased frequency of endocrine-committed cells emerging from ductal progenitor pools. These results identify M2 macrophages as key effectors capable of coordinating epithelial cell cycle withdrawal and cell migration, two events critical to pancreatic progenitors' delamination and progression toward their differentiated fates. PMID:24586821

  14. The Myth of the Phoenix: Progressive Education, Migration and the Shaping of the Welfare State, 1985-2015

    ERIC Educational Resources Information Center

    Goossens, Cedric; Van Gorp, Angelo

    2016-01-01

    Since the 1970s, many western welfare states have been subject both to increased migration and to a renewed interest in progressive education. The present article addresses the question of whether these two phenomena are related and how changing notions of the welfare state shape and are shaped by this relationship. To answer the question, we…

  15. Progress on the Fabric for Frontier Experiments Project at Fermilab

    NASA Astrophysics Data System (ADS)

    Box, Dennis; Boyd, Joseph; Dykstra, Dave; Garzoglio, Gabriele; Herner, Kenneth; Kirby, Michael; Kreymer, Arthur; Levshina, Tanya; Mhashilkar, Parag; Sharma, Neha

    2015-12-01

    The FabrIc for Frontier Experiments (FIFE) project is an ambitious, major-impact initiative within the Fermilab Scientific Computing Division designed to lead the computing model for Fermilab experiments. FIFE is a collaborative effort between experimenters and computing professionals to design and develop integrated computing models for experiments of varying needs and infrastructure. The major focus of the FIFE project is the development, deployment, and integration of Open Science Grid solutions for high throughput computing, data management, database access and collaboration within experiment. To accomplish this goal, FIFE has developed workflows that utilize Open Science Grid sites along with dedicated and commercial cloud resources. The FIFE project has made significant progress integrating into experiment computing operations several services including new job submission services, software and reference data distribution through CVMFS repositories, flexible data transfer client, and access to opportunistic resources on the Open Science Grid. The progress with current experiments and plans for expansion with additional projects will be discussed. FIFE has taken a leading role in the definition of the computing model for Fermilab experiments, aided in the design of computing for experiments beyond Fermilab, and will continue to define the future direction of high throughput computing for future physics experiments worldwide.

  16. Olympic Fisher Reintroduction Project: Progress report 2008-2011

    USGS Publications Warehouse

    Jeffrey C. Lewis,; Patti J. Happe,; Jenkins, Kurt J.; Manson, David J.

    2012-01-01

    This progress report summarizes the final year of activities of Phase I of the Olympic fisher restoration project. The intent of the Olympic fisher reintroduction project is to reestablish a self-sustaining population of fishers on the Olympic Peninsula. To achieve this goal, the Olympic fisher reintroduction project released 90 fishers within Olympic National Park from 2008 to 2010. The reintroduction of fishers to the Olympic Peninsula was designed as an adaptive management project, including the monitoring of released fishers as a means to (1) evaluate reintroduction success, (2) investigate key biological and ecological traits of fishers, and (3) inform future reintroduction, monitoring, and research efforts. This report summarizes reintroduction activities and preliminary research and monitoring results completed through December 2011. The report is non-interpretational in nature. Although we report the status of movement, survival, and home range components of the research, we have not completed final analyses and interpretation of research results. Much of the data collected during the monitoring and research project will be analyzed and interpreted in the doctoral dissertation being developed by Jeff Lewis; the completion of this dissertation is anticipated prior to April 2013. We anticipate that this work, and analyses of other data collected during the project, will result in several peer-reviewed scientific publications in ecological and conservation journals, which collectively will comprise the final reporting of work summarized here. These publications will include papers addressing post-release movements, survival, resource selection, food habits, and age determination of fishers.

  17. TraqBio - Flexible Progress Tracking for Core Unit Projects

    PubMed Central

    Schneider, Fabian; Görlach, Matthias; Kestler, Hans A.

    2016-01-01

    Motivation Core service units have become an organisational hallmark in many research institutions world wide. Such service cores provide complex state-of-the-art technologies and expertise to the research community. Typically, a user delivers material or raw data to a core. The core defines work packages for ensuing analysis and returns results back to the user. This core activity can be quite complex and time consuming and usually does not communicate itself to the outside. Naturally, the user is highly interested to follow the progress of a project once handed over to the core unit. This generates a time-intensive direct communication activity back and forth. A more effective, convenient and less disruptive way to track the status of a given project by the researcher, but also by core managers, appears highly desirable. Hence, we developed a lightweight and readily implementable web application that allows efficient progress tracking of core unit projects. Results The web application TraqBio allows for the convenient tracking of projects. Following project set-up by the core, the user receives an e-mail containing links for tracking the project status. Examples are provided for three common core units, namely genomics, proteomics, and bioinformatics units. TraqBio is a secure lightweight web application that can be either used in a standalone setup or incorporated into an existing web server infrastructure. Being accessible not only from classical desktop computers but also from mobile devices such as smartphones and tablets, TraqBio offers easy integration into every day work. PMID:27677174

  18. Function and regulation of Rnd proteins in cortical projection neuron migration

    PubMed Central

    Azzarelli, Roberta; Guillemot, François; Pacary, Emilie

    2015-01-01

    The mammalian cerebral cortex contains a high variety of neuronal subtypes that acquire precise spatial locations and form long or short-range connections to establish functional neuronal circuits. During embryonic development, cortical projection neurons are generated in the areas lining the lateral ventricles and they subsequently undergo radial migration to reach the position of their final maturation within the cortical plate. The control of the neuroblast migratory behavior and the coordination of the migration process with other neurogenic events such as cell cycle exit, differentiation and final maturation are crucial to normal brain development. Among the key regulators of cortical neuron migration, the small GTP binding proteins of the Rho family and the atypical Rnd members play important roles in integrating intracellular signaling pathways into changes in cytoskeletal dynamics and motility behavior. Here we review the role of Rnd proteins during cortical neuronal migration and we discuss both the upstream mechanisms that regulate Rnd protein activity and the downstream molecular pathways that mediate Rnd effects on cell cytoskeleton. PMID:25705175

  19. Thermally induced chemical migration: a natural analog approach. Progress report, September 1984-September 1985

    SciTech Connect

    Papike, J.J.

    1985-04-26

    The objective has been to understand the extent and mechanisms of chemical migration in the broadest sense, i.e., over a range of temperatures and in diverse geologic media. Pegmatites are genetic links between ''normal granites'' and hydrothermal systems. At some stage in their crystallization history with falling temperature (and sometimes pressure) an aqueous fluid phase exsolves and coexists with a silicate melt. Little is known about the composition of these fluids, the element partitioning behavior between fluid and silicate melt, and how these fluids interact with previously crystallized granite. It is these fluids that ''leak'' out of the pegmatites and form the dispersion halos that we are studying. Research progress is reported in the following areas: (1) fluid evolution in the Notch Peak, Utah, metamorphic aureole; (2) tourmaline as a recorder of pegmatite evolution; (3) feldspar as a recorder of pegmatite evolution; (4) the distribution of boron among pegmatite minerals and the mass balance of boron in granitic pegmatite systems; (5) crystal chemical aspects of Li, Pb, and Cs partitioning between coexisting muscovite and biotite; (6) apatite as a recorder of pegmatite petrogenesis; (7) mineralogy and REE geochemistry of an S-type granite; (8) exomorphic aureoles as indicators of pegmatite fluid composition; (9) anatomy of a layered granite pluton; and (10) fractionation within a granitic system. (ACR)

  20. Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

    PubMed Central

    Schulz, Ramona; Marchenko, Natalia D.; Holembowski, Lena; Fingerle-Rowson, Günter; Pesic, Marina; Zender, Lars; Dobbelstein, Matthias

    2012-01-01

    Intracellular macrophage migration inhibitory factor (MIF) often becomes stabilized in human cancer cells. MIF can promote tumor cell survival, and elevated MIF protein correlates with tumor aggressiveness and poor prognosis. However, the molecular mechanism facilitating MIF stabilization in tumors is not understood. We show that the tumor-activated HSP90 chaperone complex protects MIF from degradation. Pharmacological inhibition of HSP90 activity, or siRNA-mediated knockdown of HSP90 or HDAC6, destabilizes MIF in a variety of human cancer cells. The HSP90-associated E3 ubiquitin ligase CHIP mediates the ensuing proteasome-dependent MIF degradation. Cancer cells contain constitutive endogenous MIF–HSP90 complexes. siRNA-mediated MIF knockdown inhibits proliferation and triggers apoptosis of cultured human cancer cells, whereas HSP90 inhibitor-induced apoptosis is overridden by ectopic MIF expression. In the ErbB2 transgenic model of human HER2-positive breast cancer, genetic ablation of MIF delays tumor progression and prolongs overall survival of mice. Systemic treatment with the HSP90 inhibitor 17AAG reduces MIF expression and blocks growth of MIF-expressing, but not MIF-deficient, tumors. Together, these findings identify MIF as a novel HSP90 client and suggest that HSP90 inhibitors inhibit ErbB2-driven breast tumor growth at least in part by destabilizing MIF. PMID:22271573

  1. Laboratory and field studies related to the Hydrology/Radionuclide Migration Project

    SciTech Connect

    Thompson, J.L.

    1991-05-01

    This annual report describes research conducted in FY 1990 by Los Alamos National Laboratory for the Hydrology/Radionuclide Migration Project. This multi-agency project measures the underground movement of radionuclides related to nuclear testing at the Nevada Test Site. This project continues the long-term experiment at the site of the Cambric nuclear test. Water pumped from a well adjacent to the explosion cavity continues to show decreasing amounts of tritium and Krypton 85 but no Cesium 139. Analyses of drillback debris shows a distinction between refractory and volatile materials in respect to both their location in the test cavity and their leachability with groundwater. We surveyed materials used during nuclear testing to evaluate any post-test hazard; we concluded that most such materials pose a minimal hazard. The Los Alamos drilling program provided an opportunity for us to sample a collapsed zone above the cavity of a test, which was fired 2 years ago. We continue our research in colloid characterization and in detection of low levels of Technetium 99 in Nevada Test Site water. During FY 1990, we drilled a new hole in the Yucca Flat area to study radionuclide migration. This report also describes Los Alamos management and planning activities in support of this project. 20 refs., 2 figs., 14 tabs.

  2. Radionuclide migration at the Koongarra uranium deposit, Northern Australia Lessons from the Alligator Rivers analogue project

    NASA Astrophysics Data System (ADS)

    Payne, Timothy E.; Airey, Peter L.

    The Koongarra uranium deposit in Northern Australia provides a ‘natural analogue’ for processes that are of relevance for assessing the safety of radioactive waste disposal. In an international project extending over two decades, the Koongarra ore body was studied to increase the understanding of radionuclide migration and retention mechanisms that might occur in the vicinity of a geological repository. The research effort included extensive characterisation of the geological, hydrological and geochemical conditions at the site. Patterns of the distribution of radionuclides (predominantly members of the 238U decay chain, but also the rare isotopes 239Pu, 99Tc and 129I) were studied in both solid and groundwater phases. The project included detailed studies of uranium adsorption on mineral surfaces, and of subsequent processes that may lead to long-term uranium immobilisation. Numerous models for uranium migration were developed during the project. This paper provides a comprehensive review of the research at Koongarra, and assesses the value of the site for integrating the results of a complex series of laboratory, modelling and field studies. The insights gained from this review of the Koongarra project may assist in maximising the potential scientific benefit of future natural analogue studies.

  3. TPS In-Flight Health Monitoring Project Progress Report

    NASA Technical Reports Server (NTRS)

    Kostyk, Chris; Richards, Lance; Hudston, Larry; Prosser, William

    2007-01-01

    Progress in the development of new thermal protection systems (TPS) is reported. New approaches use embedded lightweight, sensitive, fiber optic strain and temperature sensors within the TPS. Goals of the program are to develop and demonstrate a prototype TPS health monitoring system, develop a thermal-based damage detection algorithm, characterize limits of sensor/system performance, and develop ea methodology transferable to new designs of TPS health monitoring systems. Tasks completed during the project helped establish confidence in understanding of both test setup and the model and validated system/sensor performance in a simple TPS structure. Other progress included complete initial system testing, commencement of the algorithm development effort, generation of a damaged thermal response characteristics database, initial development of a test plan for integration testing of proven FBG sensors in simple TPS structure, and development of partnerships to apply the technology.

  4. Advanced Neutron Source (ANS) Project. Progress report FY 1993

    SciTech Connect

    Campbell, J.H.; Selby, D.L.; Harrington, R.M.; Thompson, P.B.

    1994-01-01

    This report covers the progress made in 1993 in the following sections: (1) project management; (2) research and development; (3) design and (4) safety. The section on research and development covers the following: (1) reactor core development; (2) fuel development; (3) corrosion loop tests and analysis; (4) thermal-hydraulic loop tests; (5) reactor control and shutdown concepts; (6) critical and subcritical experiments; (7) material data, structure tests, and analysis; (8) cold source development; (9) beam tube, guide, and instrument development; (10) neutron transport and shielding; (11) I and C research and development; and (12) facility concepts.

  5. Ceramic Technology Project semiannual progress report, April 1992--September 1992

    SciTech Connect

    Johnson, D.R.

    1993-07-01

    This project was developed to meet the ceramic technology requirements of the DOE Office of Transportation Systems` automotive technology programs. Significant progress in fabricating ceramic components for DOE, NASA, and DOE advanced heat engine programs show that operation of ceramic parts in high-temperature engines is feasible; however, addition research is needed in materials and processing, design, and data base and life prediction before industry will have a sufficient technology base for producing reliable cost-effective ceramic engine components commercially. A 5-yr project plan was developed, with focus on structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines.

  6. Chemical Species of Migrating Radionuclides at Commercial Shallow Land Burial Sites: Quarterly Progress Report - October-December, 1983

    SciTech Connect

    Kirby, L. J.; RIckard, W. H.; Toste, A. P.

    1984-02-01

    The primary purpose of this project is to develop an understanding of chemical processes that significantly influence the migration of radionuclides at commercial low-level waste (LLW} burial sites. Chemical measurements of waste trench leachate and identification of chanical changes in leachate during migration will provide a basis for geochemical waste transport models. This project will produce for the U.S. Nuclear Regulatory C011mission (NRC) information to support guidance for implementation of 10 CFR 61, particularly in the developnent of criteria for low level waste disposal site selection, management, permanent closure and monitoring. This project will also produce information needed by the Canmonwealth of Kentucky as they finalize plans to stabilize. close and monitor the Maxey Flats site.

  7. Progress and status of cryogenic refrigeration system for project Hydra

    NASA Astrophysics Data System (ADS)

    Yuan, J.; Catseman, F.; Tilleman, H.; Henderson, N.

    2015-12-01

    In the last two decades, HTS cables have been successfully demonstrated around the world, preparing HTS power cables for a full commercial introduction. Among the demonstration projects, circulating subcooled liquid nitrogen to maintain the HTS cable at operating temperature is a widely adopted approach. In this approach, the cooling systems are absolutely critical to the successful operation of the HTS cables. This paper describes the progress and status of the cryogenic refrigeration system designed and manufactured for project Hydra, which is a project jointly funded by the U.S. Department of Homeland Security Science and Technology Directorate, American Superconductor and Consolidated Edison Company of New York, Inc. American Superconductor is leading the team supported by Con Edison, Ultera, Altran Solutions, and DH Industries. The cable is an inherently fault current limiting HTS cable, approximately 200 m long and designed to carry 96 MVA at a distribution level voltage of 13.8 kV. The cable will be installed and energized near New York City. The refrigeration system was designed and manufactured by DH Industries. This paper provides details on the successful factory acceptance testing completed in November 2014.

  8. Milliwatt Generator Project. Progress report, April 1986--March 1988

    SciTech Connect

    Latimer, T.W.; Rinehart, G.H.

    1992-05-01

    This report covers progress on the Milliwatt Generator Project from April 1986 through March 1988. Activities included fuel processing and characterization, production of heat sources, fabrication of pressure-burst test units, compatibility studies, impact testing, and examination of surveillance units. The major task of the Los Alamos Milliwatt Generator Project is to fabricate MC2893A heat sources (4.0 W) for MC2730A radioisotope thermoelectric generators (RTGS) and MC3599 heat sources (4.5 W) for MC3500 RTGs. The MWG Project interfaces with the following contractors: Sandia National Laboratories, Albuquerque (designer); E.I. du Pont de Nemours and Co. (Inc.), Savannah River Plant (fuel); Monsanto Research Corporation, Mound Facility (metal hardware); and General Electric Company, Neutron Devices Department (RTGs). In addition to MWG fabrication activities, Los Alamos is involved in (1) fabrication of pressure-burst test units, (2) compatibility testing and evaluation, (3) examination of surveillance units, and (4) impact testing and subsequent examination of compatibility and surveillance units.

  9. Chemical species of migrating radionuclides at commercial shallow land burial sites. Quarterly progress report, May-July, 1984

    SciTech Connect

    Kirby, L.J.; Rickard, W.H.

    1984-08-01

    The primary purposes of this project are to develop an understanding of chemical processes that significantly influence the migration of radionuclides at commercial low-level waste (LLW) burial sites and to evaluate ecological field sampling procedures for monitoring the performance of these sites. This project will produce information to support guidance for implementation of 10 CFR 61, particularly in the development of criteria for LLW disposal site selection, management, permanent closure, and monitoring. It will also produce information needed by the Commonwealth of Kentucky as they finalize plans to stabilize, close, and monitor the Maxey Flats site. Significant current research results are reported for the following tasks: inorganic and organic radionuclide species chemical forms; subsurface migration and infiltration studies; specific radionuclide mapping at Maxey Flats and commercial shallow land burial sites; ecological monitoring at commercial shallow land burial sites; and technical program coordination for LLW research. 13 references, 4 figures, 1 table.

  10. Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 87

    SciTech Connect

    1997-10-01

    Approximately 30 research projects are summarized in this report. Title of the project, contract number, company or university, award amount, principal investigators, objectives, and summary of technical progress are given for each project. Enhanced oil recovery projects include chemical flooding, gas displacement, and thermal recovery. Most of the research projects though are related to geoscience technology and reservoir characterization.

  11. Progress of the NASA/USGS Lunar Regolith Simulant Project

    NASA Technical Reports Server (NTRS)

    Rickman, Doug; MLemore, Carole; Wilson, Steve; Stoeser, Doug; Schrader, Christian; Fikes, John; Street, Kenneth

    2009-01-01

    Beginning in 2004 personnel at MSFC began serious efforts to develop a new generation of lunar simulants. The first two products were a replication of the previous JSC-1 simulant under a contract to Orbitec and a major workshop in 2005 on future simulant development. Beginning in 2006 the project refocused its efforts and approached simulant development in a new and more comprehensive manner, examining new approaches in simulant development and ways to more accurately compare simulants to actual lunar materials. This led to a multi-year effort with five major tasks running in parallel. The five tasks are Requirements, Lunar Analysis, Process Development, Feed Stocks, and Standards. Major progress has been made in all five areas. A substantial draft of a formal requirements document now exists and has been largely stable since 2007. It does evolve as specific details of the standards and Lunar Analysis efforts proceed. Lunar Analysis has turned out to be vastly more difficult than anticipated. After great effort to mine existing published and gray literature, the team has realized the necessity of making new measurements of the Apollo samples, an effort that is currently in progress. Process development is substantially ahead of expectations in 2006. It is now practical to synthesize glasses of appropriate composition and purity. It is also possible to make agglutinate particles in significant quantities. A series of minerals commonly found on the Moon has been synthesized. Separation of mineral constituents from starting rock material is also proceeding. Customized grinding and mixing processes have been developed and tested are now being documented. Identification and development of appropriate feedstocks has been both easier and more difficult than anticipated. The Stillwater Mining Company, operating in the Stillwater layered mafic intrusive complex of Montana, has been an amazing resource for the project, but finding adequate sources for some of the components

  12. Progress Report on the TIBET AS+MD Project

    NASA Astrophysics Data System (ADS)

    Amenomori, M.; Bi, X. J.; Chen, D.; Chen, T. L.; Chen, W. Y.; Cui, S. W.; Danzengluobu; Ding, L. K.; Feng, C. F.; Feng, Zhaoyang; Feng, Z. Y.; Gou, Q. B.; Guo, Y. Q.; He, H. H.; He, Z. T.; Hibino, K.; Hotta, N.; Hu, Haibing; Hu, H. B.; Huang, J.; Jia, H. Y.; Jiang, L.; Kajino, F.; Kasahara, K.; Katayose, Y.; Kato, C.; Kawata, K.; Kozai, M.; Labaciren; Le, G. M.; Li, A. F.; Li, H. J.; Li, W. J.; Liu, C.; Liu, J. S.; Liu, M. Y.; Lu, H.; Meng, X. R.; Mizutani, K.; Munakata, K.; Nanjo, H.; Nishizawa, M.; Ohnishi, M.; Ohta, I.; Ozawa, S.; Qian, X. L.; Qu, X. B.; Saito, T.; Saito, T. Y.; Sakata, M.; Sako, T. K.; Shao, J.; Shibata, M.; Shiomi, A.; Shirai, T.; Sugimoto, H.; Takita, M.; Tan, Y. H.; Tateyama, N.; Torii, S.; Tsuchiya, H.; Udo, S.; Wang, H.; Wu, H. R.; Xue, L.; Yamamoto, Y.; Yang, Z.; Yasue, S.; Yuan, A. F.; Yuda, T.; Zhai, L. M.; Zhang, H. M.; Zhang, J. L.; Zhang, X. Y.; Zhang, Y.; Zhang, Yi; Zhang, Ying; Zhaxisangzhu; Zhou, X. X.

    We plan to build a large (approximately 10,000 m2) water-Cherenkov-type muon detector array under the existing Tibet air shower array at 4,300 m above sea level, to observe 10-1000 TeV gamma rays from cosmic-ray accelerators in our Galaxy with wide field of view at very low background level. The gamma-ray induced air shower has significantly less muons compared with a cosmic-ray induced one. Therefore, we can effectively discriminate between primary gamma rays and cosmic-ray background events by means of counting the number of muons in an air shower by the muon detector array. We will make a progress report on the project, as 5/12 of it is under construction now.

  13. Chemical species of migrating radionuclides at commercial shallow land burial sites. Quarterly progress report, July-September 1983

    SciTech Connect

    Kirby, L.J.; Rickard, W.H.; Toste, A.P.

    1983-11-01

    The primary purpose of this project is to develop an understanding of chemical processes that significantly influence the migration of radionuclides at commercial low-level waste burial sites. Chemical measurements of waste trench leachate and identification of chemical changes in leachate during migration will provide a basis for geochemical waste transport models. This project will produce for the US Nuclear Regulatory Commission (NRC) information to support guidance for implementation of 10 CFR 61, particularly in the development of criteria for low level waste disposal site selection, management, permanent closure and monitoring. This project will also produce information needed by the Commonwealth of Kentucky as they finalize plans to stabilize, close and monitor the Maxey Flats site. Current research results are presented for the following tasks: (1) chemical forms inorganic and organic radionuclide species; (2) subsurface migration and infiltration studies; (3) specific radionuclide mapping at Maxey Flats and other commercial shallow land burial sites; (4) ecological monitoring at commercial shallow land burial sites; and (5) technical program coordination for low-level waste research. 17 references, 6 figures, 3 tables.

  14. Lincoln County nuclear waste project. Quarterly progress report, October 1, 1991--December 31, 1991

    SciTech Connect

    1996-03-01

    This document included the following three progress reports to the Yucca Mountain Project Office on radioactive waste storage in Lincoln County, Nevada: financial status report; federal cash transactions report; and technical progress report.

  15. Integrated multidisciplinary fault observation in Marmara Through MARSite - Project Progress

    NASA Astrophysics Data System (ADS)

    Meral Ozel, Nurcan; Necmioglu, Ocal; Oguz Ozel, Asım; Ergintav, Semih; Geli, Louis Louis; Favali, Paolo; Guralp, Cansun; Douglas, John; Mathieu, Pierre-Philippe; Tan, Onur; Gürbüz, Cemil; Erdik, Mustafa

    2015-04-01

    This presentation provides a progress overview of the EC/FP-7 MARSite Project started in November 2012, which aims to coordinate research groups ranging from seismology to gas geochemistry in a comprehensive monitoring activity developed both in the Marmara Region based on collection of multidisciplinary data to be shared, interpreted and merged in consistent theoretical and practical models suitable for the implementation of good practices to move the necessary information to the end users in charge of seismic risk management of the region. In addition, processes involved in earthquake generation and the physics of short-term seismic transients, 4D deformations to understand earthquake cycle processes, fluid activity monitoring and seismicity under the sea floor using existing autonomous instrumentation, early warning and development of real-time shake and loss information, real- and quasi-real-time earthquake and tsunami hazard monitoring and earthquake-induced landslide hazard topics are also covered within MARSite. This presentation would provide a report on the progress achieved during the half-life of the project. In this respect, the main data server for the integration of real time network data has been finalized. Daily evaluation of online spring water and soil radon gas data in relation to seismic activity is in place, together with the continuous GPS data processing. A significant combination of postseismic (viscoelastic) deformation and afterslip was detected in the western segment of the 1999 Izmit rupture plane based on InSAR modeling. The optimum borehole depths have been identified based on seismic reflection studies and GURALP Systems is continuing its work on the manufacturing the borehole system. Seismic risk study for IGDAS Natural Gas Network including pipelines and its components has been carried out with several earthquake scenarios in Marmara Sea and an automatic shut-off algorithm has been developed for the automatic shut-off of the gas

  16. Walla Walla River Fish Passage Operations Project : Annual Progress Report October 2007 - September 2008.

    SciTech Connect

    Bronson, James P.; Duke, Bill; Loffink, Ken

    2008-12-30

    In the late 1990s, the Confederated Tribes of the Umatilla Indian Reservation, Oregon Department of Fish and Wildlife, and Washington Department of Fish and Wildlife, along with many other agencies, began implementing fisheries restoration activities in the Walla Walla Basin. An integral part of these efforts is to alleviate the inadequate fish migration conditions in the basin. Migration concerns are being addressed by removing diversion structures, constructing fish passage facilities, implementing minimum instream flow requirements, and providing trap and haul efforts when needed. The objective of the Walla Walla River Fish Passage Operations Project is to increase the survival of migrating adult and juvenile salmonids in the Walla Walla River basin. The project is responsible for coordinating operation and maintenance of ladders, screen sites, bypasses, trap facilities, and transportation equipment. In addition, the project provides technical input on passage and trapping facility design, operation, and criteria. Operation of the various passage facilities and passage criteria guidelines are outlined in an annual operations plan that the project develops. Beginning in March of 2007, two work elements from the Walla Walla Fish Passage Operations Project were transferred to other projects. The work element Enumeration of Adult Migration at Nursery Bridge Dam is now conducted under the Walla Walla Basin Natural Production Monitoring and Evaluation Project and the work element Provide Transportation Assistance is conducted under the Umatilla Satellite Facilities Operation and Maintenance Project. Details of these activities can be found in those project's respective annual reports.

  17. Projects at the Component Development and Integration Facility. Quarterly technical progress report, July 1--September 30, 1993

    SciTech Connect

    Not Available

    1993-12-31

    This quarterly technical progress report presents progress on the projects at the Component Development and Integration Facility (CDIF) during the first quarter of FY94. The CDIF is a major US Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: MHD Proof-of-Concept project; mine waste technology pilot program; plasma projects; resource recovery project; sodium sulfide/ferrous sulfate project; soil washing project; and spray casting project.

  18. Projects at the Component Development and Integration Facility. Quarterly technical progress report, April 1--June 30, 1993

    SciTech Connect

    Not Available

    1993-12-01

    This quarterly technical progress report presents progress on the projects at the Component Development and Integration Facility (CDIF) during the third quarter of FY93. The CDIF is a major US Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: MHD Proof-of-Concept Project; Mine Waste Technology Program; Plasma Projects; Resource Recovery Project; Sodium Sulfide/Ferrous Sulfate Project; Soil Washing Project; and Spray Casting Project.

  19. Projects at the Component Development and Integration Facility. Quarterly technical progress report, January 1, 1994--March 31, 1994

    SciTech Connect

    Not Available

    1994-08-01

    This quarterly technical progress report presents progress on the projects at the Component Development and Integration Facility (CDIF) during the second quarter of FY94. The CDIF is a major US Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Pilot Program; Plasma Projects; Resource Recovery Project; Sodium Sulfide/Ferrous Sulfate Project; and Spray Casting Project.

  20. Great Basin paleoenvironmental studies project; Technical progress report: First quarter (January--August 1993)

    SciTech Connect

    1993-12-31

    Project goals, project tasks, progress on tasks, and problems encountered are described and discussed for each of the studies that make up the Great Basin Paleoenvironmental Studies Project for Yucca Mountain. These studies are: Paleobotany, Paleofauna, Geomorphology, and Transportation. Budget summaries are also given for each of the studies and for the overall project.

  1. Progress report for project modeling Arctic barrier island-lagoon system response to projected Arctic warming

    USGS Publications Warehouse

    Erikson, Li H.; Gibbs, Ann E.; Richmond, Bruce M.; Storlazzi, Curt; B.M. Jones,

    2012-01-01

    Changes in Arctic coastal ecosystems in response to global warming may be some of the most severe on the planet. A better understanding and analysis of the rates at which these changes are expected to occur over the coming decades is crucial in order to delineate high-priority areas that are likely to be affected by climate changes. In this study we investigate the likelihood of changes to habitat-supporting barrier island – lagoon systems in response to projected changes in atmospheric and oceanographic forcing associated with Arctic warming. To better understand the relative importance of processes responsible for the current and future coastal landscape, key parameters related to increasing arctic temperatures are investigated and used to establish boundary conditions for models that simulate barrier island migration and inundation of deltaic deposits and low-lying tundra. The modeling effort investigates the dominance and relative importance of physical processes shaping the modern Arctic coastline as well as decadal responses due to projected conditions out to the year 2100.

  2. DEVELOPING AND IMPLEMENTING A BIRD MIGRATION MONITORING, ASSESSMENT AND PUBLIC OUTREACH PROGRAM FOR YOUR COMMUNITY - THE BIRDCAST PROJECT

    EPA Science Inventory

    The USEPA has developed a technology transfer handbook for the EMPACt BirdCast bird migration monitoring project. The document is essentially a "How-To" Handbook that addresses the planning and implementation steps that were needed to develop, operate and maintain a program simil...

  3. PFTK1 Promotes Gastric Cancer Progression by Regulating Proliferation, Migration and Invasion.

    PubMed

    Yang, Lei; Zhu, Jia; Huang, Hua; Yang, Qichang; Cai, Jing; Wang, Qiuhong; Zhu, Junya; Shao, Mengting; Xiao, Jinzhang; Cao, Jie; Gu, Xiaodan; Zhang, Shusen; Wang, Yingying

    2015-01-01

    PFTK1, also known as PFTAIRE1, CDK14, is a novel member of Cdc2-related serine/threonine protein kinases. Recent studies show that PFTK1 is highly expressed in several malignant tumors such as hepatocellular carcinoma, esophageal cancer, breast cancer, and involved in regulation of cell cycle, tumors proliferation, migration, and invasion that further influence the prognosis of tumors. However, the expression and physiological significance of PFTK1 in gastric cancer remain unclear. In this study, we analyzed the expression and clinical significance of PFTK1 by Western blot in 8 paired fresh gastric cancer tissues, nontumorous gastric mucosal tissues and immunohistochemistry on 161 paraffinembedded slices. High PFTK1 expression was correlated with the tumor grade, lymph node invasion as well as Ki-67. Through Cell Counting Kit (CCK)-8 assay, flow cytometry, colony formation, wound healing and transwell assays, the vitro studies demonstrated that PFTK1 overexpression promoted proliferation, migration and invasion of gastric cancer cells, while PFTK1 knockdown led to the opposite results. Our findings for the first time supported that PFTK1 might play an important role in the regulation of gastric cancer proliferation, migration and would provide a novel promising therapeutic strategy against human gastric cancer.

  4. Evansville Area Earthquake Hazards Mapping Project (EAEHMP) - Progress Report, 2008

    USGS Publications Warehouse

    Boyd, Oliver S.; Haase, Jennifer L.; Moore, David W.

    2009-01-01

    Maps of surficial geology, deterministic and probabilistic seismic hazard, and liquefaction potential index have been prepared by various members of the Evansville Area Earthquake Hazard Mapping Project for seven quadrangles in the Evansville, Indiana, and Henderson, Kentucky, metropolitan areas. The surficial geologic maps feature 23 types of surficial geologic deposits, artificial fill, and undifferentiated bedrock outcrop and include alluvial and lake deposits of the Ohio River valley. Probabilistic and deterministic seismic hazard and liquefaction hazard mapping is made possible by drawing on a wealth of information including surficial geologic maps, water well logs, and in-situ testing profiles using the cone penetration test, standard penetration test, down-hole shear wave velocity tests, and seismic refraction tests. These data were compiled and collected with contributions from the Indiana Geological Survey, Kentucky Geological Survey, Illinois State Geological Survey, United States Geological Survey, and Purdue University. Hazard map products are in progress and are expected to be completed by the end of 2009, with a public roll out in early 2010. Preliminary results suggest that there is a 2 percent probability that peak ground accelerations of about 0.3 g will be exceeded in much of the study area within 50 years, which is similar to the 2002 USGS National Seismic Hazard Maps for a firm rock site value. Accelerations as high as 0.4-0.5 g may be exceeded along the edge of the Ohio River basin. Most of the region outside of the river basin has a low liquefaction potential index (LPI), where the probability that LPI is greater than 5 (that is, there is a high potential for liquefaction) for a M7.7 New Madrid type event is only 20-30 percent. Within the river basin, most of the region has high LPI, where the probability that LPI is greater than 5 for a New Madrid type event is 80-100 percent.

  5. Project Impact: A Progress Report on the Innotech Project Impact in the Philippines and Proyek Pamong in Indonesia.

    ERIC Educational Resources Information Center

    Sanger, Clyde

    A pilot project (to run from 1974 to 1979) to improve the delivery system of primary education in rural areas of the Philippines (Project Impact) and Indonesia (Proyek Pamong) is described in this progress report. Underway in seven villages, the experiment (aimed specifically at increasing schooling opportunities for young people in the Third…

  6. Project CHILD: Progress in Restructuring Schools to Tap Technology's Potential.

    ERIC Educational Resources Information Center

    Butzin, Sarah M.

    1991-01-01

    Project CHILD is a research and development project for grades K-5, which covers reading, language arts, thinking skills, and mathematics. Project CHILD provides the model, supporting materials, and applications of technology. Three classrooms form a CHILD cluster (K-2 and 3-5); each teacher becomes a subject specialist; and the children work in…

  7. Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development

    PubMed Central

    Ohtaka-Maruyama, Chiaki; Okado, Haruo

    2015-01-01

    Glutamatergic neurons of the mammalian cerebral cortex originate from radial glia (RG) progenitors in the ventricular zone (VZ). During corticogenesis, neuroblasts migrate toward the pial surface using two different migration modes. One is multipolar (MP) migration with random directional movement, and the other is locomotion, which is a unidirectional movement guided by the RG fiber. After reaching their final destination, the neurons finalize their migration by terminal translocation, which is followed by maturation via dendrite extension to initiate synaptogenesis and thereby complete neural circuit formation. This switching of migration modes during cortical development is unique in mammals, which suggests that the RG-guided locomotion mode may contribute to the evolution of the mammalian neocortical 6-layer structure. Many factors have been reported to be involved in the regulation of this radial neuronal migration process. In general, the radial migration can be largely divided into four steps; (1) maintenance and departure from the VZ of neural progenitor cells, (2) MP migration and transition to bipolar cells, (3) RG-guided locomotion, and (4) terminal translocation and dendrite maturation. Among these, many different gene mutations or knockdown effects have resulted in failure of the MP to bipolar transition (step 2), suggesting that it is a critical step, particularly in radial migration. Moreover, this transition occurs at the subplate layer. In this review, we summarize recent advances in our understanding of the molecular mechanisms underlying each of these steps. Finally, we discuss the evolutionary aspects of neuronal migration in corticogenesis. PMID:26733777

  8. LNG projects make progress in Oman and Yemen

    SciTech Connect

    1997-02-24

    Two LNG projects in the Middle East, one in Oman and the other in Yemen, are due on stream at the turn of the century--each the largest single project ever put together in its country. Officials described their projects at a yearend 1996 conference in Paris by Institut Francais du Petrole and Petrostrategies. The Oman project develops gas reserves, does gas processing, and transports the gas 360 km to a liquefaction plant to be built on the coast. The Yemen project involves a liquefaction plant and an export terminal.

  9. Progressive migration and anagenesis in Drimys confertifolia of the Juan Fernández Archipelago, Chile.

    PubMed

    López-Sepúlveda, Patricio; Takayama, Koji; Greimler, Josef; Crawford, Daniel J; Peñailillo, Patricio; Baeza, Marcelo; Ruiz, Eduardo; Kohl, Gudrun; Tremetsberger, Karin; Gatica, Alejandro; Letelier, Luis; Novoa, Patricio; Novak, Johannes; Stuessy, Tod F

    2015-01-01

    A common mode of speciation in oceanic islands is by anagenesis, wherein an immigrant arrives and through time transforms by mutation, recombination, and drift into a morphologically and genetically distinct species, with the new species accumulating a high level of genetic diversity. We investigate speciation in Drimys confertifolia, endemic to the two major islands of the Juan Fernández Archipelago, Chile, to determine genetic consequences of anagenesis, to examine relationships among populations of D. confertifolia and the continental species D. winteri and D. andina, and to test probable migration routes between the major islands. Population genetic analyses were conducted using AFLPs and nuclear microsatellites of 421 individuals from 42 populations from the Juan Fernández islands and the continent. Drimys confertifolia shows a wide genetic variation within populations on both islands, and values of genetic diversity within populations are similar to those found within populations of the continental progenitor. The genetic results are compatible with the hypothesis of high levels of genetic variation accumulating within anagenetically derived species in oceanic islands, and with the concept of little or no geographical partitioning of this variation over the landscape. Analysis of the probability of migration within the archipelago confirms colonization from the older island, Robinson Crusoe, to the younger island Alejandro Selkirk.

  10. Subsurface mass migration at active volcanoes: what we learnt from the VOLUME project

    NASA Astrophysics Data System (ADS)

    Saccorotti, G.; Volume Team

    2009-04-01

    Movements of multiphase fluids beneath active volcanoes are generally detected at the surface in terms of changes in geophysical and geochemical observables. The prompt detection and interpretation of such signals thus represent a crucial step toward the short-term evaluation of volcanic hazard. Funded through the European 6th framework program, the VOLUME project joined 19 institutions from 6 EU and 5 extra-european countries under the common goal of improving our understanding of how subsurface mass movement manifests itself at the surface, in turn revealing the significance of such movements as precursors to impending eruptions. We integrated high-end experimental procedures with a robust modeling framework to address some of the most relevant issues of modern, quantitative volcanology. In particular, our studies focused on: (i) Unrevealing the complex interplay between hydrothermal and magmatic fluids in generating the observed geophysical / geochemical signals, (ii) Detailing the location, geometry and dynamics of magma pathways and storage zones (iii) Probing variations of the elastic parameters of volcanic media in response to stress changes induced by mass migration, and (iv) Developing a robust computational framework for forward-modelling the geophysical observables resulting from the dynamics of multiphase magmatic systems. VOLUME activities developed at both european and extra-european volcanoes. We present here the most striking results obtained at two italian test-sites, namely Etna and Campi Flegrei, for which we had available data sets of unprecedented sensitivity and temporal resolution. Results from Etna include a) mapping of the shallow plumbing system from Moment-Tensor inversion of broadband seismic signal, b) the detection of deep magma intrusion from inversion of joint gravity-tremor anomalies; c) the measurement of changes in both elastic anisotropy and seismic velocity concomitant to the waning stage of the 2002 NE flank lava effusion; and

  11. CAP 5: Progress Report on the Center Accreditation Project

    ERIC Educational Resources Information Center

    Young Children, 1983

    1983-01-01

    Discusses the progress of development of a nationwide voluntary accreditation system for early childhood centers and schools, reviewing the accreditation process and providing a draft describing criteria for high quality programs. (BJD)

  12. Quarterly Technical Progress Report - West Hackberry Tertiary Project

    SciTech Connect

    Bruce Cerveny; Tor Kragas; Travis Gillham

    1997-07-10

    The West Hackberry Tertiary Project is a field test of the concept that air injection can generate tertiary oil recovery through the Double Displacement Process is the gas displacement of a water invaded oil column for the purpose of recovering tertiary oil through gravity discharge. The novel aspect of this project is the use of air as the injection fluid.

  13. Quarterly Technical Progress Report - West Hackberry Tertiary Project

    SciTech Connect

    Demetrois Yannimaras; Travis Gillham

    1998-04-15

    The West Hackberry Tertiary Project is a field test of the concept that air injection can generate tertiary oil recovery through the Double Displacement Process is the gas displacement of a water invaded oil column for the purpose of recovering tertiary oil through gravity discharge. The novel aspect of this project is the use of air as the injection fluid.

  14. Oregon Migrant Health Project; Annual Progress Report 1969.

    ERIC Educational Resources Information Center

    Oregon State Board of Health, Portland.

    In this 1969 annual report, 10 objectives of the Oregon Migrant Health Project--which served approximately 18,400 migrants during the project year--are listed. These objectives relate to providing for diagnostic and medical services, preventive medical services, and dental care, as well as promoting health awareness, education, and improved living…

  15. The Columbia Classroom Environments Project.... Fifth Progress Report, May 1972.

    ERIC Educational Resources Information Center

    Grannis, Joseph C.

    This report is organized into seven chapters. Chapter One, an Introduction by Joseph C. Grannis, includes the most relevant sections of the proposal made by the Columbia Classroom Environments Project (CCEP) to Project Follow Through in August 1970. Chapter Two is an Analysis of the Child Behavior Stream Observations from the Spring 1971 Study of…

  16. Skilled craftswomen or cheap labour? Craft-based NGO projects as an alternative to female urban migration in northern Thailand.

    PubMed

    Humphreys, R

    1999-07-01

    This article presents a craft-based nongovernmental organization (NGO) project designed as an alternative to female urban migration in northern Thailand. ThaiCraft works with over 60 community-based artisan groups including members of minority and refugee groups. Activities include supporting community groups in their move toward self-reliance, coordination of producers' activities for ensuring fair payment, and maximizing marketing opportunities to increase producers' income. One of the project¿s aims is to form dynamic educational partnerships among producers, volunteers, and the public through the provision of training. Still, it is doubtful whether craft-based NGOs and other organizations can constitute a viable long-term alternative to urban migration. No proposed solution can respond to all issues associated with the emigration of rural Thai women for employment; however, the recognition of women's skills and knowledge is of importance to the fight against gender inequality in development.

  17. Steelhead Supplementation in Idaho Rivers : 2001 Project Progress Report.

    SciTech Connect

    Byrne, Alan

    2002-03-01

    In 2001, Idaho Department of Fish and Game (IDFG) continued an assessment of the Sawtooth Hatchery steelhead Oncorhynchus mykiss stock to reestablish natural populations in Beaver and Frenchman creeks in the upper Salmon River. Crews stocked both streams with 20 pair of hatchery adults, and I estimated the potential smolt production from the 2000 adult outplants. n the Red River drainage, IDFG stocked Dworshak hatchery stock fingerlings and smolts from 1993 to 1999 to assess which life stage produces more progeny when the adults return to spawn. In 2001, IDFG operated the Red River weir to trap adults that returned from these stockings, but none were caught from either group. Wild steelhead populations in the Lochsa and Selway river drainages were assessed and the chinook salmon Oncorhynchus tshawytscha escapement was enumerated in Fish Creek. I estimated that 75 wild adult steelhead and 122 adult chinook salmon returned to Fish Creek in 2001. I estimated that slightly more than 30,000 juvenile steelhead migrated out of Fish Creek. This is the largest number of steelhead to migrate out of Fish Creek in a single year since I began estimating the yearly migration in 1994. Juvenile steelhead densities in Lochsa and Selway tributaries were somewhat higher in 2001 than those observed in 2000. Crews from IDFG collected over 4,800 fin samples from wild steelhead in 74 streams of the Clearwater, Snake, and Salmon river drainages and from five hatchery stocks during the summer of 2000 for a DNA analysis to assess Idaho's steelhead stock structure. The DNA analysis was subcontracted to Dr. Jennifer Nielsen, Alaska Biological Science Center, Anchorage. Her lab developed protocols to use for the analysis in 2001 and is continuing to analyze the samples. Dr. Nielsen plans to have the complete set of wild and hatchery stocks analyzed in 2002.

  18. Progressive migration of slab break-off along the southern Tyrrhenian plate boundary: Constraints for the present day kinematics

    NASA Astrophysics Data System (ADS)

    Chiarabba, Claudio; Palano, Mimmo

    2017-04-01

    The Ionian subduction in the central Mediterranean, just 200 km wide, is one of the narrowest in the world. Its evolution has involved a progressive disruption of the subducting slab, contemporaneous to the retreat and step-wise opening of back-arc basins. In this study, we analyse velocity anomalies of the upper mantle, together with the most comprehensive set of earthquake locations and kinematic indicators available for Italy, to reconstruct the geodynamics and tectonic evolution of the Ionian subduction system. Along the Sicilian boundary, we identify an eastward migration of the slab edge with detachment of the Ionian oceanic lithosphere. We hypothesize that the progressive detachment of the slab took place along lithospheric transform faults of the Neo-Tethys Ocean. Among the main active kinematic elements of the Ionian accretionary wedge, we suggest that a ∼400-km-long and highly segmented shear zone formed by the Aeolian-Tindari-Letojanni fault system and the Ionian fault represents the surface expression of such a lithospheric tearing. The present day convergence between the Eurasian and African plates is accommodated both at the frontal thrust of the flexed Hyblean margin in southern Sicily and offshore along the Tyrrhenian Sea. Lithospheric bending favors the wedging of the mantle underneath northern Sicily, while magmatic fluids are channeled along slab tears.

  19. 7 CFR 3402.23 - Documentation of progress on funded projects.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... database contains narrative project information, progress/impact statements, and final technical reports... reports may be needed to assess continuing progress of Fellows supported by any special international... five-year grant duration, HEP may request a preliminary exit report. In such a case, a final...

  20. 7 CFR 3402.23 - Documentation of progress on funded projects.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... database contains narrative project information, progress/impact statements, and final technical reports... reports may be needed to assess continuing progress of Fellows supported by any special international... five-year grant duration, HEP may request a preliminary exit report. In such a case, a final...

  1. 7 CFR 3402.23 - Documentation of progress on funded projects.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... database contains narrative project information, progress/impact statements, and final technical reports... reports may be needed to assess continuing progress of Fellows supported by any special international... five-year grant duration, HEP may request a preliminary exit report. In such a case, a final...

  2. 7 CFR 3402.23 - Documentation of progress on funded projects.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... database contains narrative project information, progress/impact statements, and final technical reports... reports may be needed to assess continuing progress of Fellows supported by any special international... five-year grant duration, HEP may request a preliminary exit report. In such a case, a final...

  3. Magma Energy Research Project, FY80 annual progress report

    SciTech Connect

    Colp, J.L.

    1982-04-01

    The technical feasibility of extracting energy from magma bodies is explored. Five aspects of the project are studied: resource location and definition, source tapping, magma characterization, magma/material compatibility, and energy extraction.

  4. Fifteenmile Basin Habitat Enhancement Project, 1986-1988 Progress Report.

    SciTech Connect

    Cain, Thomas C.; Hutchinson, Corey Sue; MacDonald, Ken

    1989-01-01

    The Fifteenmile Basin Habitat Improvement Project is an ongoing multi-agency effort to improve habitat in the Fifteenmile drainage and increase production of the depressed wild, winter steelhead run. Cooperating agencies include the Oregon Department of Fish and Wildlife, USDA Forest Service. USDA Soil Conservation Service and Bonneville Power Administration. in consultation with the Confederated Tribes of Warm Springs. The Oregon Department of Fish and Wildlife is administering project work on state and private lands and the U.S.D.A. Forest Service is administering project work on National Forest land. Project work on the Forest has been sub-divided into four components; (1) Ramsey Creek, (2) Eightmile Creek, (3) Fifteenmile Creek, and (4) Fivemile Creek. Forest Service activities in the Fifteenmile basin during 1988 involved habitat improvement work on Ramsey Creek, continuation of physical and biological monitoring, collection of spawning survey information, and macroinvertebrate sampling. The primary project objective on Ramsey Creek was to increase juvenile rearing habitat for 1+ steelhead. A total of 48 log structures including sills, diggers, wings and diagonal series were constructed in two project areas.

  5. Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression

    PubMed Central

    Henderson, Veronica; Smith, Basil; Burton, Liza J; Randle, Diandra; Morris, Marisha; Odero-Marah, Valerie A

    2015-01-01

    Snail, a zinc-finger transcription factor, induces epithelial-mesenchymal transition (EMT), which is associated with increased cell migration and metastasis in cancer cells. Rac1 is a small G-protein which upon activation results in formation of lamellipodia, the first protrusions formed by migrating cells. We have previously shown that Snail promotes cell migration through down-regulation of maspin tumor suppressor. We hypothesized that Snail's regulation of cell migration may also involve Rac1 signaling regulated by PI3K/AKT and/or MAPK pathways. We found that Snail overexpression in LNCaP and 22Rv1 prostate cancer cells increased Rac1 activity associated with increased cell migration, and the Rac1 inhibitor, NSC23766, could inhibit Snail-mediated cell migration. Conversely, Snail downregulation using shRNA in the aggressive C4–2 prostate cancer cells decreased Rac1 activity and cell migration. Moreover, Snail overexpression increased ERK and PI3K/AKT activity in 22Rv1 prostate cancer cells. Treatment of Snail-overexpressing 22Rv1 cells with LY294002, PI3K/AKT inhibitor or U0126, MEK inhibitor, decreased cell migration significantly, but only LY294002 significantly reduced Rac1 activity, suggesting that Snail promotes Rac1 activation via the PI3K/AKT pathway. Furthermore, 22Rv1 cells overexpressing Snail displayed decreased maspin levels, while inhibition of maspin expression in 22Rv1 cells with siRNA, led to increased PI3K/AKT, Rac1 activity and cell migration, without affecting ERK activity, suggesting that maspin is upstream of PI3K/AKT. Overall, we have dissected signaling pathways by which Snail may promote cell migration through MAPK signaling or alternatively through PI3K/AKT-Rac1 signaling that involves Snail inhibition of maspin tumor suppressor. This may contribute to prostate cancer progression. PMID:26207671

  6. Canadian Environmental Concerns: Winnipeg, Manitoba. Progress Report. Project Canada West.

    ERIC Educational Resources Information Center

    Western Curriculum Project on Canada Studies, Edmonton (Alberta).

    Part I of this progress report places emphasis on curriculum development from the standpoint of the teacher-developer. The role is defined and factors such as teacher selection, release time, administrative cooperation, work schedules, assigned work space, and benefits to the school division and to the teacher are discussed. Recommendations deal…

  7. Elevated Serum Levels of Macrophage Migration Inhibitory Factor Are Associated with Progressive Chronic Cardiomyopathy in Patients with Chagas Disease

    PubMed Central

    Cutrullis, Romina A.; Petray, Patricia B.; Schapachnik, Edgardo; Sánchez, Rubén; Postan, Miriam; González, Mariela N.; Martín, Valentina; Corral, Ricardo S.

    2013-01-01

    Clinical symptoms of chronic Chagas disease occur in around 30% of the individuals infected with Trypanosoma cruzi and are characterized by heart inflammation and dysfunction. The pathogenesis of chronic chagasic cardiomyopathy (CCC) is not completely understood yet, partially because disease evolution depends on complex host-parasite interactions. Macrophage migration inhibitory factor (MIF) is a pleiotropic proinflammatory cytokine that promotes numerous pathophysiological processes. In the current study, we investigated the link between MIF and CCC progression. Immunohistochemical analysis demonstrated MIF overexpression in the hearts from chronically T. cruzi-infected mice, particularly those showing intense inflammatory infiltration. We also found that MIF exogenously added to parasite-infected murine macrophage cultures is capable of enhancing the production of TNF-α and reactive oxygen species, both with pathogenic roles in CCC. Thus, the integrated action of MIF and other cytokines and chemokines may account for leukocyte influx to the infected myocardium, accompanied by enhanced local production of multiple inflammatory mediators. We further examined by ELISA the level of MIF in the sera from chronic indeterminate and cardiomyopathic chagasic patients, and healthy subjects. CCC patients displayed significantly higher MIF concentrations than those recorded in asymptomatic T. cruzi-infected and uninfected individuals. Interestingly, increased MIF levels were associated with severe progressive Chagas heart disease, in correlation with elevated serum concentration of high sensitivity C-reactive protein and also with several echocardiographic indicators of left ventricular dysfunction, one of the hallmarks of CCC. Our present findings represent the first evidence that enhanced MIF production is associated with progressive cardiac impairment in chronic human infection with T. cruzi, strengthening the relationship between inflammatory response and parasite

  8. The Second Year of the Brookline Early Education Project: Progress Report and Plans for the Future.

    ERIC Educational Resources Information Center

    Brookline Public Schools, MA.

    This is the second in a series of progress reports on the Brookline Early Education Project (BEEP), a program which provides diagnostic and educational services for very young children and their families. The 1972-74 programs are described, and plans for the following 3-year period are reviewed. The purpose of this pilot project of the Brookline…

  9. Palm Beach County Health Department Migrant Project, Annual Progress Report, 1972-73.

    ERIC Educational Resources Information Center

    Palm Beach County Health Dept., West Palm Beach, FL.

    Information about the Palm Beach County Health Department Migrant Project for 1972 is presented in this annual progress report. Information on services provided by the Project as prescribed by the Migrant Health Branch is included. Major topics include program objectives, relationships and contributions, staff orientation and training, a general…

  10. FLORIDA MIGRANT HEALTH PROJECT. FOURTH ANNUAL PROGRESS REPORT, 1966-1967.

    ERIC Educational Resources Information Center

    Florida State Board of Health, Jacksonville.

    THE FOURTH ANNUAL PROGRESS REPORT OF THE FLORIDA MIGRANT HEALTH PROJECT INDICATES THAT IN 1966-67 THERE WAS AN APPRECIABLE INCREASE IN THE AMOUNT AND VARIETY OF MIGRANT HEALTH SERVICES RENDERED, THE NUMBER OF MIGRANTS CONTACTED, AND THE ACTIVITIES PERFORMED BY PROJECT PERSONNEL. MIGRANT HEALTH SERVICE REFERRALS INCREASED BY 1,222 OVER THE SAME…

  11. Human liver proteome project: plan, progress, and perspectives.

    PubMed

    He, Fuchu

    2005-12-01

    The Human Liver Proteome Project is the first initiative of the human proteome project for human organs/tissues and aims at writing a modern Prometheus myth. Its global scientific objectives are to reveal the "solar system" of the human liver proteome, expression profiles, modification profiles, a protein linkage (protein-protein interaction) map, and a proteome localization map, and to define an ORFeome, physiome, and pathome. Since it was first proposed in April 2002, the Human Liver Proteome Project has attracted more than 100 laboratories from all over the world. In the ensuing 3 years, we set up a management infrastructure, identified reference laboratories, confirmed standard operating procedures, initiated international research collaborations, and finally achieved the first set of expression profile data.

  12. Progress, status, and plans for the HRIBF project

    SciTech Connect

    Auble, R.L.; Alton, G.D.; Bailey, J.D

    1995-12-31

    Over the last three years, the Holifield accelerator system has been reconfigured into a first-generation radioactive ion beam facility, the HRIBF, a national user facility for RIB research. The construction and reconfiguration have been completed and the equipment commissioning and beam development phases have started. The progress to date, the present status, and future plans will be given. The special problems connected with the production and acceleration of RIBs will be discussed.

  13. Progress, status, and plans for the HRIBF project

    NASA Astrophysics Data System (ADS)

    Olsen, D. K.; Auble, R. L.; Alton, G. D.; Bailey, J. D.; Dinehart, M. R.; Dukes, C. L.; Dowling, D. T.; Haynes, D. L.; Jones, C. M.; Lane, S. N.; LeCroy, C. T.; Juras, R. C.; Meigs, M. J.; Mills, G. D.; Mosko, S. W.; Mueller, P. E.; Murray, S. N.; Tatum, B. A.; Welton, R. F.; Wollnik, H.

    1996-02-01

    Over the last three years, the Holifield accelerator system has been reconfigured into a first-generation radioactive ion beam facility, the HRIBF, a national user facility for RIB research. The construction and reconfiguration have been completed and the equipment commissioning and beam development phases have started. The progress to date, the present status, and future plans will be given. The special problems connected with the production and acceleration of RIBs will be discussed.

  14. Progress Report 15, December 1979-April 1980, and proceedings of the fifteenth Project Integration Meeting

    SciTech Connect

    Not Available

    1980-01-01

    Progress made by the Low-Cost Solar Array Project during the period December 1979 to April 1980 is reported. Reports on project analysis and integration; technology development in silicon material, large-area silicon sheet and encapsulation; production process and equipment development; engineering; and operations are included. Also, a report on, and copies of visual presentations made at, the Project Integration Meeting held April 2 and 3, 1980, are included.

  15. Doctoral Projects in Progress in Theatre Arts, 1983.

    ERIC Educational Resources Information Center

    Hill, Philip G.

    1983-01-01

    Thirty-first annual listing of dissertations arranged by subject according to geographical divisions. Entries include researchers's name, title of project, institution, academic department, faculty supervisor, and expected date of completion. Available from American Theatre Assoc. 1010 Wisconsin Ave., N.W., Suite 630, Washington, D.C. 20007; sc…

  16. The Shongololo Interconnectivity Pilot Project: A Work in Progress

    ERIC Educational Resources Information Center

    Rosario, Joy; Molapo, Lunga

    2005-01-01

    The Shongololo project of the KwaZulu-Natal Department of Education and Culture in South Africa aims to endorse the notion that a school can quite effectively cross the digital divide with a single online computer that is accessible to both learners and educators and which is managed by an enthusiastic and committed information…

  17. Doctoral Projects in Progress in Theatre Arts, 1982.

    ERIC Educational Resources Information Center

    Hill, Philip G.

    1982-01-01

    Thirtieth annual listing of dissertations, arranged, for the most part, by subject according to geographical divisions. Entries include researcher's name, title of project, institution, academic department, faculty supervisor, and expected date of completion. Available from American Theatre Assn., 1000 Vermont Ave., N.W., Washington, DC 20005, sc…

  18. Aboriginal Language Standardisation Project: Progress Report, 2000. Literacy Ontario.

    ERIC Educational Resources Information Center

    Ontario Ministry of Training, Colleges and Universities, Toronto. Literacy and Basic Skills Section.

    The Aboriginal Language Standardisation (ALS) Project's task is to develop quality literacy materials in order to help preserve aboriginal languages of Canada. The Canadian Assembly of First Nations, a group of tribal leaders, recently called for the establishment of standards for written and oral languages by approving terminology, developing…

  19. Ceramic Technology Project. Semiannual progress report, April 1991--September 1991

    SciTech Connect

    Not Available

    1992-03-01

    The Ceramic Technology Project was developed by the USDOE Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS`s Materials Development Program, was developed to meet the ceramic technology requirements of the OTS`s automotive technology programs. Significant accomplishments in fabricating ceramic components for the USDOE and NASA advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. These programs have also demonstrated that additional research is needed in materials and processing development, design methodology, and data base and life prediction before industry will have a sufficient technology base from which to produce reliable cost-effective ceramic engine components commercially. A five-year project plan was developed with extensive input from private industry. In July 1990 the original plan was updated through the estimated completion of development in 1993. The objective is to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. The project approach includes determining the mechanisms controlling reliability, improving processes for fabricating existing ceramics, developing new materials with increased reliability, and testing these materials in simulated engine environments to confirm reliability. Although this is a generic materials project, the focus is on the structural ceramics for advanced gas turbine and diesel engines, ceramic bearings and attachments, and ceramic coatings for thermal barrier and wear applications in these engines. To facilitate the rapid transfer of this technology to US industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities.

  20. Advanced Neutron Source (ANS) Project Progress report, FY 1991

    SciTech Connect

    Campbell, J.H. ); Selby, D.L.; Harrington, R.M. ); Thompson, P.B. . Engineering Division)

    1992-01-01

    This report discusses the following about the Advanced Neutron Source: Project Management; Research and Development; Fuel Development; Corrosion Loop Tests and Analyses; Thermal-Hydraulic Loop Tests; Reactor Control and Shutdown Concepts; Critical and Subcritical Experiments; Material Data, Structural Tests, and Analysis; Cold-Source Development; Beam Tube, Guide, and Instrument Development; Hot-Source Development; Neutron Transport and Shielding; I C Research and Development; Design; and Safety.

  1. Advanced Neutron Source (ANS) Project Progress report, FY 1991

    SciTech Connect

    Campbell, J.H.; Selby, D.L.; Harrington, R.M.; Thompson, P.B.

    1992-01-01

    This report discusses the following about the Advanced Neutron Source: Project Management; Research and Development; Fuel Development; Corrosion Loop Tests and Analyses; Thermal-Hydraulic Loop Tests; Reactor Control and Shutdown Concepts; Critical and Subcritical Experiments; Material Data, Structural Tests, and Analysis; Cold-Source Development; Beam Tube, Guide, and Instrument Development; Hot-Source Development; Neutron Transport and Shielding; I & C Research and Development; Design; and Safety.

  2. Caribbean LNG project marks progress; LNG tanker launched

    SciTech Connect

    1997-10-20

    World LNG trade continues to expand as construction of a major LNG project in the Caribbean hits full stride this fall and another LNG carrier was launched earlier this year. Engineering is nearly complete and construction is nearing midway on Trinidad`s Atlantic LNG. In Japan, NKK Corp. launched another LNG tanker that employs the membrane-storage system. The 50-mile pipeline to move natural gas to the Atlantic LNG facility is also on track for completion by October 1998.

  3. Progress of excimer laser development in the AMMTRA project

    NASA Astrophysics Data System (ADS)

    Nagai, Haruhiko

    1993-05-01

    Since 1986, five kinds of excimer laser technologies have been studied by five companies as part of the large-scale project `Advanced Material-Processing and Machining System,' which is one of the national R&D projects in Japan. The five kinds of excimer lasers being developed are as follows: (1) high power XeCl laser with an average power of 2 kW, (2) high repetition rate XeCl laser with a repetition rate of 5 kHz, (3) automatically power-stabilized 400 W average power XeCl laser with a stability of +/- 1% or less, (4) long-life ArF laser with a gas life of 109 shots or more, and (5) high beam-quality ArF laser with an average power of 200 W. The project passed an interim evaluation at the end of fiscal 1990, and is now ongoing toward the achievement of final targets as of the end of fiscal 1993. The present status and future prospect of the technologies are reviewed.

  4. DOE project on genome mapping and sequencing. Progress report, 1992

    SciTech Connect

    Evans, G.A.

    1992-12-31

    These efforts on the human genome project were initiated in September, 1990, to contribute towards completion of the human genome project physical mapping effort. In the original application, the authors proposed a novel strategy for constructing a physical map of human chromosome 11, based upon techniques derived in this group and by others. The original goals were to (1) produce a set of cosmid reference clones mapped to specific sites by high resolution fluorescence in situ hybridization, (2) produce a set of associated STS sequences and PCR primers for each site, (3) isolate YAC clones corresponding to each STS and, (4) construct YAC contigs such that > 90% of the chromosome would be covered by contigs of 2 mb or greater. Since that time, and with the advent of new technology and reagents, the strategy has been modified slightly but still retains the same goals as originally proposed. The authors have added a project to produce chromosome 11-specific cDNAs and determine the map location and DNA sequence of a selected portion of them.

  5. Out-migration and land-use change in agricultural frontiers: insights from Altamira settlement project.

    PubMed

    Vanwey, Leah K; Guedes, Gilvan R; D'Antona, Alvaro O

    2012-09-01

    One of Daniel Hogan's lasting impacts on international demography community comes through his advocacy for studying bidirectional relationships between environment and demography, particularly migration. We build on his holistic approach to mobility and examine dynamic changes in land use and migration among small farm families in Altamira, Pará, Brazil. We find that prior area in either pasture or perennials promotes out-migration of adult children, but that out-migration is not directly associated with land-use change. In contrast to early formulations of household life cycle models that argued that aging parents would decrease productive land use as children left the farm, we find no effect of out-migration of adult children on land-use change. Instead, remittances facilitate increases in area in perennials, a slower to pay off investment that requires scarce capital, but in pasture. While remittances are rare, they appear to permit sound investments in the rural milieu and thus to slow rural exodus and the potential consolidation of land into large holdings. We would do well to promote the conditions that allow them to be sent and to be used productively to keep families on the land to avoid the specter of extensive deforestation for pasture followed by land consolidation.

  6. Out-migration and land-use change in agricultural frontiers: insights from Altamira settlement project

    PubMed Central

    D’Antona, Álvaro O.

    2012-01-01

    One of Daniel Hogan’s lasting impacts on international demography community comes through his advocacy for studying bidirectional relationships between environment and demography, particularly migration. We build on his holistic approach to mobility and examine dynamic changes in land use and migration among small farm families in Altamira, Pará, Brazil. We find that prior area in either pasture or perennials promotes out-migration of adult children, but that out-migration is not directly associated with land-use change. In contrast to early formulations of household life cycle models that argued that aging parents would decrease productive land use as children left the farm, we find no effect of out-migration of adult children on land-use change. Instead, remittances facilitate increases in area in perennials, a slower to pay off investment that requires scarce capital, but in pasture. While remittances are rare, they appear to permit sound investments in the rural milieu and thus to slow rural exodus and the potential consolidation of land into large holdings. We would do well to promote the conditions that allow them to be sent and to be used productively to keep families on the land to avoid the specter of extensive deforestation for pasture followed by land consolidation. PMID:23129878

  7. Increasing the realism of projected tree species ranges by incorporating migration potential: an eastern US case study

    NASA Astrophysics Data System (ADS)

    Rogers, B. M.; Jantz, P.; Goetz, S. J.

    2015-12-01

    Models of vegetation distributions are used for a wide variety of purposes, from global assessments of biome shifts and biogeochemical feedbacks to local management planning. Dynamic vegetation models, mostly mechanistic in origin, are valuable for regional to global studies but remain limited for more local-scale applications, especially those that require species-specific responses to climate change. Species distribution models (SDMs) are broadly used for such applications, but these too have several outstanding limitations, one of the most prominent being a lack of dispersal and migration. Several hybrid models have recently been developed, but these generally require detailed parameterization of species-level attributes that may not be known. Here we present an approach to couple migration potential with SDM output for a large number of species in order to more realistically project future range shifts. We focus on 40 tree species in the eastern US of potential management concern, either because of their canopy dominance, ecosystem functions, or potential for utilizing future climates. Future climates were taken from a CMIP5 model ensemble average using RCP 4.5 and 8.5 scenarios. We used Random Forests to characterize current and future environmental suitability, and modeled migration as a negative exponential kernel that is affected by forest fragmentation and the density of current seed sources. We present results in a vulnerability framework relevant for a number of ongoing management activities in the region. We find an overarching pattern of northward and eastward range shifts, with high-elevation and northern species being the most adversely impacted. Because of limitations to migration, many newly suitable areas could not be utilized without active intervention. Only a few areas exhibited consistently favorable conditions that could be utilized by the relevant species, including the central Appalachian foothills and the Florida panhandle. We suggest that

  8. MiR-146b negatively regulates migration and delays progression of T-cell acute lymphoblastic leukemia

    PubMed Central

    Correia, Nádia C.; Fragoso, Rita; Carvalho, Tânia; Enguita, Francisco J.; Barata, João T.

    2016-01-01

    Previous results indicated that miR-146b-5p is downregulated by TAL1, a transcription factor critical for early hematopoiesis that is frequently overexpressed in T-cell acute lymphoblastic leukemia (T-ALL) where it has an oncogenic role. Here, we confirmed that miR-146b-5p expression is lower in TAL1-positive patient samples than in other T-ALL cases. Furthermore, leukemia T-cells display decreased levels of miR-146b-5p as compared to normal T-cells, thymocytes and other hematopoietic progenitors. MiR-146b-5p silencing enhances the in vitro migration and invasion of T-ALL cells, associated with increased levels of filamentous actin and chemokinesis. In vivo, miR-146b overexpression in a TAL1-positive cell line extends mouse survival in a xenotransplant model of human T-ALL. In contrast, knockdown of miR-146b-5p results in leukemia acceleration and decreased mouse overall survival, paralleled by faster tumor infiltration of the central nervous system. Our results suggest that miR-146b-5p is a functionally relevant microRNA gene in the context of T-ALL, whose negative regulation by TAL1 and possibly other oncogenes contributes to disease progression by modulating leukemia cell motility and disease aggressiveness. PMID:27550837

  9. CDC Periodontal Disease Surveillance Project: background, objectives, and progress report.

    PubMed

    Eke, Paul I; Genco, Robert J

    2007-07-01

    This supplement contains papers presented at the 2006 International Association of Dental Research (IADR) symposium entitled "Development of Self-Reported Measures for Population-Based Surveillance of Periodontitis." These papers highlight activities of an independent periodontal disease surveillance workgroup convened by the Division of Oral Health (DOH), Centers for Disease Control and Prevention (CDC), in collaboration with the American Academy of Periodontology, to examine the feasibility of using self-reported measures for population-based surveillance of periodontal disease in the United States. This workgroup was convened in 2003 as part of a CDC periodontal disease surveillance project.

  10. Plutonium Reclamation Facility incident response project progress report

    SciTech Connect

    Austin, B.A.

    1997-11-25

    This report provides status of Hanford activities in response to process deficiencies highlighted during and in response to the May 14, 1997, explosion at the Plutonium Reclamation Facility. This report provides specific response to the August 4, 1997, memorandum from the Secretary which requested a progress report, in 120 days, on activities associated with reassessing the known and evaluating new vulnerabilities (chemical and radiological) at facilities that have been shut down, are in standby, are being deactivated or have otherwise changed their conventional mode of operation in the last several years. In addition, this report is intended to provide status on emergency response corrective activities as requested in the memorandum from the Secretary on August 28, 1997. Status is also included for actions requested in the second August 28, 1997, memorandum from the Secretary, regarding timely notification of emergencies.

  11. Advanced Neutron Source (ANS) Project progress report, FY 1994

    SciTech Connect

    Campbell, J.H.; King-Jones, K.H.; Selby, D.L.; Harrington, R.M.; Thompson, P.B.

    1995-01-01

    The President`s budget request for FY 1994 included a construction project for the Advanced Neutron Source (ANS). However, the budget that emerged from the Congress did not, and so activities during this reporting period were limited to continued research and development and to advanced conceptual design. A significant effort was devoted to a study, requested by the US Department of Energy (DOE) and led by Brookhaven National Laboratory, of the performance and cost impacts of reducing the uranium fuel enrichment below the baseline design value of 93%. The study also considered alternative core designs that might mitigate those impacts. The ANS Project proposed a modified core design, with three fuel elements instead of two, that would allow operation with only 50% enriched uranium and use existing fuel technology. The performance penalty would be 15--20% loss of thermal neutron flux; the flux would still just meet the minimum design requirement set by the user community. At the time of this writing, DOE has not established an enrichment level for ANS, but two advisory committees have recommended adopting the new core design, provided the minimum flux requirements are still met.

  12. Tunneling on the Yucca Mountain Project: Progress and lessons learned

    SciTech Connect

    Hansmire, W.H.; Rogers, D.J.; Wightman, W.D.

    1996-06-01

    The Yucca Mountain Site Characterization Project is the US`s effort to confirm the technical acceptability of Yucca Mountain as a repository for high-level nuclear waste. A key part of the site characterization project is the construction of a 7.8-km-long, 7.6-m-diameter tunnel for in-depth geologic and other scientific investigations. The work is governed in varying degrees by the special requirements for nuclear quality assurance, which imposes uncommon and often stringent limitations on the materials which can be used in construction, the tunneling methods and procedures used, and record-keeping for many activities. This paper presents the current status of what has been learned, how construction has adapted to meet the requirements, and how the requirements were interpreted in a mitigating way to meet the legal obligations, yet build the tunnel as rapidly as possible. With regard to design methodologies and the realities of tunnel construction, ground support with a shielded Tunnel Boring Machine is discussed. Notable lessons learned include the need for broad design analyses for a wide variety of conditions and how construction procedures affect ground support.

  13. Ceramic Technology Project. Semiannual progress report for April 1993 through September 1993

    SciTech Connect

    Not Available

    1994-04-01

    The Ceramic Technology Project was originally developed by the Department of Energy`s Office of Transportation Systems (OTS) in Conservation and Renewable Energy. This project, part of the OTS`s Materials Development Program, was developed to meet the ceramic technology requirements of the OTS`s automotive technology programs. During the course of the Ceramic Technology Project, remarkable progress has been made in the development of reliable structural ceramics. However, further work is needed to reduce the cost of ceramics to facilitate their commercial introduction, especially in the highly cost-sensitive automotive market. The work described in this report is organized according to the following WBS project elements: Project Management and Coordination; Materials and Processing; Materials Design Methodology; Data Base and Life Prediction; and Technology Transfer. This report includes contributions from all currently active project participants. Separate abstracts were prepared for the 47 projects reported here.

  14. Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells.

    PubMed

    Zhang, Ying-Ying; Li, Gang; Che, Hui; Sun, Hai-Ying; Xiao, Guo-Sheng; Wang, Yan; Li, Gui-Rong

    2015-01-01

    Our previous study demonstrated that a large-conductance Ca2+-activated K+ current (BKCa), a voltage-gated TTX-sensitive sodium current (INa.TTX), and an inward rectifier K+ current (IKir) were heterogeneously present in most of human cardiac c-kit+ progenitor cells. The present study was designed to investigate the effects of these ion channels on cell cycling progression and migration of human cardiac c-kit+ progenitor cells with approaches of cell proliferation and mobility assays, siRNA, RT-PCR, Western blots, flow cytometry analysis, etc. It was found that inhibition of BKCa with paxilline, but not INa.TTX with tetrodotoxin, decreased both cell proliferation and migration. Inhibition of IKir with Ba2+ had no effect on cell proliferation, while enhanced cell mobility. Silencing KCa.1.1 reduced cell proliferation by accumulating the cells at G0/G1 phase and decreased cell mobility. Interestingly, silencing Kir2.1 increased the cell migration without affecting cell cycling progression. These results demonstrate the novel information that blockade or silence of BKCa channels, but not INa.TTX channels, decreases cell cycling progression and mobility, whereas inhibition of Kir2.1 channels increases cell mobility without affecting cell cycling progression in human cardiac c-kit+ progenitor cells.

  15. Effects of BKCa and Kir2.1 Channels on Cell Cycling Progression and Migration in Human Cardiac c-kit+ Progenitor Cells

    PubMed Central

    Zhang, Ying-Ying; Li, Gang; Che, Hui; Sun, Hai-Ying; Xiao, Guo-Sheng; Wang, Yan; Li, Gui-Rong

    2015-01-01

    Our previous study demonstrated that a large-conductance Ca2+-activated K+ current (BKCa), a voltage-gated TTX-sensitive sodium current (INa.TTX), and an inward rectifier K+ current (IKir) were heterogeneously present in most of human cardiac c-kit+ progenitor cells. The present study was designed to investigate the effects of these ion channels on cell cycling progression and migration of human cardiac c-kit+ progenitor cells with approaches of cell proliferation and mobility assays, siRNA, RT-PCR, Western blots, flow cytometry analysis, etc. It was found that inhibition of BKCa with paxilline, but not INa.TTX with tetrodotoxin, decreased both cell proliferation and migration. Inhibition of IKir with Ba2+ had no effect on cell proliferation, while enhanced cell mobility. Silencing KCa.1.1 reduced cell proliferation by accumulating the cells at G0/G1 phase and decreased cell mobility. Interestingly, silencing Kir2.1 increased the cell migration without affecting cell cycling progression. These results demonstrate the novel information that blockade or silence of BKCa channels, but not INa.TTX channels, decreases cell cycling progression and mobility, whereas inhibition of Kir2.1 channels increases cell mobility without affecting cell cycling progression in human cardiac c-kit+ progenitor cells. PMID:26390131

  16. Manchester Spring Chinook Broodstock Project : Progress Report, 2000.

    SciTech Connect

    McAuley, W. Carlin; Wastel, Michael R.; Flagg, Thomas A.

    2000-11-01

    In spring 1995 the Idaho Department of Fish and Game (IDFG) and the Oregon Department of Fish and Wildlife (ODFW) initiated captive broodstocks as part of conservation efforts for ESA-listed stocks of Snake River spring/summer chinook salmon (Oncorhynchus tshawytscha). The need for this captive broodstock strategy was identified as critical in the National Marine Fisheries Service (NMFS) Proposed Recovery Plan for Snake River Salmon. These captive broodstock programs are being coordinated by the Bonneville Power Administration (BPA) through the Chinook Salmon Captive Propagation Technical Oversight Committee (CSCPTOC). Oregon's Snake River spring/summer chinook salmon captive broodstock program currently focuses on three stocks captured as juveniles from the Grande Ronde River Basin: the upper Grande Ronde River, Catherine Creek, and the Lostine River. Idaho's Snake River program includes three stocks captured as eggs and juveniles from the Salmon River Basin: the Lemhi River, East Fork Salmon River, and West Fork Yankee Fork. The majority of captive fish from each stock of the Grande Ronde Basin will be grown to maturity in freshwater at the ODFW Bonneville Hatchery. A minority of the Salmon River Basin stocks will be grown to maturity in freshwater at the IDFG Eagle Hatchery. However, the IDFG and ODFW requested that a portion of each group also be reared in protective culture in seawater. In August 1996, NMFS began a BPA funded project (Project 96-067-00) to rear Snake River spring/summer chinook salmon captive broodstocks in seawater at the NMFS Manchester Research Station. During 1997-1999, facilities modifications were undertaken at Manchester to provide secure facilities for rearing of these ESA-listed fish. This included construction of a building housing a total of twenty 6.1-m diameter fiberglass rearing tanks, upgrade of the Manchester salt water pumping and filtration/sterilization systems to a total capacity of 5,670 L/min (1,500 gpm), and installation

  17. Progress towards implementing the e-Bug Project in Poland.

    PubMed

    Olczak-Pienkowska, Anna; Grzesiowski, Pawel

    2011-06-01

    The e-Bug Project provides useful educational tools that can be implemented in primary and secondary schools, and plays important role in reducing the burden of community-acquired infections. Consideration of the Polish education system and educational programmes in schools facilitated the selection of the best age groups for the implementation of e-Bug materials in Poland. The Polish version of the resources has been reviewed by a special group of experts and teachers from pilot schools. The pilot implementation is currently provided by demonstration lessons for educators and recorded as a demonstration material. The e-Bug teaching pack is a valuable resource that is useful for improving knowledge about microorganisms, hygiene and antimicrobial agents, and is aimed at pupils, teachers and parents.

  18. Project 3000 by 2000. Progress to Date. Year Four Progress Report.

    ERIC Educational Resources Information Center

    Association of American Medical Colleges, Washington, DC.

    The Association of American Medical Colleges launched Project 3000 by 2000 in November 1991 to address the under-representation of Blacks, American Indians, Mexican Americans, and Mainland Puerto Ricans in medical schools. Its aim is to increase the number of under-represented minorities to entering medical schools to 3,000 by the year 2000. Since…

  19. The Subaru Coronagraphic Extreme AO Project: Progress and Upgrades

    NASA Astrophysics Data System (ADS)

    Jovanovic, Nemanja; Martinache, F.; Guyon, O.; Clergeon, C.; Garrel, V.

    2013-01-01

    The Subaru Coronagraphic Extreme AO (SCExAO) instrument consists of a high performance Phase Induced Amplitude Apodisation (PIAA) coronagraph combined with an extreme Adaptive Optics (AO) system operating in the near-infrared (H band). The extreme AO system driven by the 2000 element deformable mirror will allow for Strehl ratios>90% to be achieved in the H-band when it goes closed loop. This makes the SCExAO instrument a powerful platform for high contrast imaging down to angular separations of the order of 1 λ/D. In this paper we report on the recent progress in regards to the development of the instrument, which includes the addition of a visible bench that makes use of the light at shorter wavelengths not currently utilized by SCExAO and closing the loop on the tip/tilt wavefront sensor. We will also discuss two exciting guest instruments which will expand the capabilities of SCExAO over the next few years; namely CHARIS which is a integral field spectrograph as well as VAMPIRES, a visible aperture masking experiment based on polarimetric analysis of circumstellar disks.

  20. Instrumentation progress at the Giant Magellan Telescope project

    NASA Astrophysics Data System (ADS)

    Jacoby, George H.; Bernstein, R.; Bouchez, A.; Colless, M.; Crane, Jeff; DePoy, D.; Espeland, B.; Hare, Tyson; Jaffe, D.; Lawrence, J.; Marshall, J.; McGregor, P.; Shectman, Stephen; Sharp, R.; Szentgyorgyi, A.; Uomoto, Alan; Walls, B.

    2016-08-01

    Instrument development for the 24m Giant Magellan Telescope (GMT) is described: current activities, progress, status, and schedule. One instrument team has completed its preliminary design and is currently beginning its final design (GCLEF, an optical 350-950 nm, high-resolution and precision radial velocity echelle spectrograph). A second instrument team is in its conceptual design phase (GMACS, an optical 350-950 nm, medium resolution, 6-10 arcmin field, multi-object spectrograph). A third instrument team is midway through its preliminary design phase (GMTIFS, a near-IR YJHK diffraction-limited imager/integral-field-spectrograph), focused on risk reduction prototyping and design optimization. A fourth instrument team is currently fabricating the 5 silicon immersion gratings needed to begin its preliminary design phase (GMTNIRS, a simultaneous JHKLM high-resolution, AO-fed, echelle spectrograph). And, another instrument team is focusing on technical development and prototyping (MANIFEST, a facility robotic, multifiber feed, with a 20 arcmin field of view). In addition, a medium-field (6 arcmin, 0.06 arcsec/pix) optical imager will support telescope and AO commissioning activities, and will excel at narrow-band imaging. In the spirit of advancing synergies with other groups, the challenges of running an ELT instrument program and opportunities for cross-ELT collaborations are discussed.

  1. Progress of the LASL dry hot rock geothermal energy project

    NASA Technical Reports Server (NTRS)

    Smith, M. C.

    1974-01-01

    The possibilities and problems of extracting energy from geothermal reservoirs which do not spontaneously yield useful amounts of steam or hot water are discussed. The system for accomplishing this which is being developed first is a pressurized-water circulation loop intended for use in relatively impermeable hot rock. It will consist of two holes connected through the hot rock by a very large hydraulic fracture and connected at the surface through the primary heat exchanger of an energy utilization system. Preliminary experiments in a hole 2576 ft (0.7852 km) deep, extending about 470 ft (143 m) into the Precambrian basement rock underlying the Jemez Plateau of north-central New Mexico, revealed no unexpected difficulties in drilling or hydraulically fracturing such rock at a temperature of approximately 100 C, and demonstrated a permeability low enough so that it appeared probable that pressurized water could be contained by the basement rock. Similar experiments are in progress in a second hole, now 6701 ft (2.043 km) deep, about 1.5 miles (2.4 km) south of the first one.

  2. Recent Progress of the Series-Connected Hybrid Magnet Projects

    SciTech Connect

    Adkins, Todd; Bole, Scott

    2010-01-01

    The National High Magnetic Field Laboratory (NHMFL) in Tallahassee, Florida has designed and is now constructing two Series Connected Hybrid (SCH) magnets, each connecting a superconducting outsert coil and a resistive Florida Bitter insert coil electrically in series. The SCH to be installed at the NHMFL will produce 36 T and provide 1 ppm maximum field inhomogeneity over a 1 cm diameter spherical volume. The SCH to be installed at the Helmholtz Center Berlin (HZB) in combination with a neutron source will produce 25 T to 30 T depending on the resistive insert. The two magnets have a common design for their cable-in-conduit conductor (CICC) and superconducting outsert coils. The CICC outsert coil winding packs have an inner diameter of 0.6 m and contribute 13.1 T to the central field using three grades of CICC conductors. Each conductor grade carries 20 kA and employs the same type of Nb{sub 3}Sn superconducting wire, but each grade contains different quantities of superconducting wires, different cabling patterns and different aspect ratios. The cryostats and resistive insert coils for the two magnets are different. This paper discusses the progress in CIC conductor and coil fabrication over the last year including specification, qualification and production activities for wire, cable, conductor and coil processing.

  3. Geothermal direct-heat utilization assistance. Quarterly project progress report, April--June 1993

    SciTech Connect

    Lienau, P.

    1993-06-01

    Technical assistance was provided to 60 requests from 19 states. R&D progress is reported on: evaluation of lineshaft turbine pump problems, geothermal district heating marketing strategy, and greenhouse peaking analysis. Two presentations and one tour were conducted, and three technical papers were prepared. The Geothermal Progress Monitor reported: USGS Forum on Mineral Resources, Renewable Energy Tax Credits Not Working as Congress Intended, Geothermal Industry Tells House Panel, Newberry Pilot Project, and Low-Temperature Geothermal Resources in Nevada.

  4. Design implementation and migration of security systems as an extreme project.

    SciTech Connect

    Scharmer, Carol

    2010-10-01

    Decision Trees, algorithms, software code, risk management, reports, plans, drawings, change control, presentations, and analysis - all useful tools and efforts but time consuming, resource intensive, and potentially costly for projects that have absolute schedule and budget constraints. What are necessary and prudent efforts when a customer calls with a major security problem that needs to be fixed with a proven, off-the-approval-list, multi-layered integrated system with high visibility and limited funding and expires at the end of the Fiscal Year? Whether driven by budget cycles, safety, or by management decree, many such projects begin with generic scopes and funding allocated based on a rapid management 'guestimate.' Then a Project Manager (PM) is assigned a project with a predefined and potentially limited scope, compressed schedule, and potentially insufficient funding. The PM is tasked to rapidly and cost effectively coordinate a requirements-based design, implementation, test, and turnover of a fully operational system to the customer, all while the customer is operating and maintaining an existing security system. Many project management manuals call this an impossible project that should not be attempted. However, security is serious business and the reality is that rapid deployment of proven systems via an 'Extreme Project' is sometimes necessary. Extreme Projects can be wildly successful but require a dedicated team of security professionals lead by an experienced project manager using a highly-tailored and agile project management process with management support at all levels, all combined with significant interface with the customer. This paper does not advocate such projects or condone eliminating the valuable analysis and project management techniques. Indeed, having worked on a well-planned project provides the basis for experienced team members to complete Extreme Projects. This paper does, however, provide insight into what it takes for projects

  5. Design, implementation and migration of security systems as an extreme project.

    SciTech Connect

    Scharmer, Carol; Trujillo, David

    2010-08-01

    Decision Trees, algorithms, software code, risk management, reports, plans, drawings, change control, presentations, and analysis - all useful tools and efforts but time consuming, resource intensive, and potentially costly for projects that have absolute schedule and budget constraints. What are necessary and prudent efforts when a customer calls with a major security problem that needs to be fixed with a proven, off-the-approval-list, multi-layered integrated system with high visibility and limited funding and expires at the end of the Fiscal Year? Whether driven by budget cycles, safety, or by management decree, many such projects begin with generic scopes and funding allocated based on a rapid management 'guestimate.' Then a Project Manager (PM) is assigned a project with a predefined and potentially limited scope, compressed schedule, and potentially insufficient funding. The PM is tasked to rapidly and cost effectively coordinate a requirements-based design, implementation, test, and turnover of a fully operational system to the customer, all while the customer is operating and maintaining an existing security system. Many project management manuals call this an impossible project that should not be attempted. However, security is serious business and the reality is that rapid deployment of proven systems via an 'Extreme Project' is sometimes necessary. Extreme Projects can be wildly successful but require a dedicated team of security professionals lead by an experienced project manager using a highly-tailored and agile project management process with management support at all levels, all combined with significant interface with the customer. This paper does not advocate such projects or condone eliminating the valuable analysis and project management techniques. Indeed, having worked on a well-planned project provides the basis for experienced team members to complete Extreme Projects. This paper does, however, provide insight into what it takes for projects

  6. Progress of the NASAUSGS Lunar Regolith Simulant Project

    NASA Technical Reports Server (NTRS)

    Rickman, Douglas; McLemore, C.; Stoeser, D.; Schrader, C.; Fikes, J.; Street, K.

    2009-01-01

    Beginning in 2004 personnel at MSFC began serious efforts to develop a new generation of lunar simulants. The first two products were a replication of the previous JSC-1 simulant under a contract to Orbitec and a major workshop in 2005 on future simulant development. It was recognized in early 2006 there were serious limitations with the standard approach of simply taking a single terrestrial rock and grinding it. To a geologist, even a cursory examination of the Lunar Sourcebook shows that matching lunar heterogeneity, crystal size, relative mineral abundances, lack of H2O, plagioclase chemistry and glass abundance simply can not be done with any simple combination of terrestrial rocks. Thus the project refocused its efforts and approached simulant development in a new and more comprehensive manner, examining new approaches in simulant development and ways to more accurately compare simulants to actual lunar materials. This led to a multi-year effort with five major tasks running in parallel. The five tasks are Requirements, Lunar Analysis, Process Development, Feed Stocks, and Standards.

  7. The New Progress of the Starry Sky Project of China

    NASA Astrophysics Data System (ADS)

    Wang, Xiaohua

    2015-08-01

    Since the 28th General Assembly of IAU, the SSPC team made new progress:1. Enhanced the function of the SSPC team-- Established the contact with IAU C50, IUCN Dark Skies Advisory Group, AWB and IDA,and undertakes the work of the IDA Beijing Chapter.-- Got supports from China’s National Astronomical Observatories, Beijing Planetarium, and Shanghai Science and Technology Museum.-- Signed cooperation agreements with Lighting Research Center, English Education Group and law Firm; formed the team force.2. Put forward a proposal to national top institutionThe SSPC submitted the first proposal about dark sky protection to the Chinese People’s Political Consultative Conference.3. Introduced the Criteria and Guideline of dark sky protectionThe SSPC team translated 8 documents of IDA, and provided a reference basis for Chinese dark sky protection.4. Actively establish dark sky places-- Plan a Dark Sky Reserve around Ali astronomical observatory (5,100m elevation) in Tibet. China’s Xinhua News Agency released the news.-- Combining with Hangcuo Lake, a National Natural Reserve and Scenic in Tibet, to plan and establish the Dark Sky Park.-- Cooperated with Shandong Longgang Tourism Group to construct the Dream Sky Theme Park in the suburbs of Jinan city.In the IYL 2015, the SSPC is getting further development:First, make dark sky protection enter National Ecological Strategy of “Beautiful China”. We call on: “Beautiful China” needs “Beautiful Night Sky” China should care the shared starry sky, and left this resource and heritage for children.Second, hold “Cosmic Light” exhibition in Shanghai Science and Technology Museum on August.Third, continue to establish Dark Sky Reserve, Park and Theme Park. We want to make these places become the bases of dark sky protection, astronomical education and ecological tourism, and develop into new cultural industry.Fourth, actively join international cooperation.Now, “Blue Sky, White Cloud and Starry Sky “have become

  8. MIGRESIVES: a research project on migration from adhesives in food-packaging materials in support of European legislation and standardization.

    PubMed

    Störmer, A; Franz, R

    2009-12-01

    Most food packages and food-contact materials are manufactured using adhesives. The European Union regulates all food-contact materials, as their constituents may not contaminate food and endanger consumers' health. In contrast to plastics which are regulated by positive lists of authorized ingredients, adhesives have not yet a specific regulation. The MIGRESIVES project aimed to elaborate a scientific global risk-assessment approach to meet current general European Union regulatory requirements and as a basis for future specific European Union legislation as well as to provide the industry, especially small and medium-sized enterprises, a tool to ensure that migration from adhesives is in compliance with the regulatory requirements. The idea was to demonstrate that consumers' exposure to chemicals released by adhesives is in many cases below levels of concern. Technical/scientific knowledge from industry and research institutes will be merged into a collective research endeavour gathering all stakeholders. The major milestones are (1) the classification of adhesives according to chemistry and uses, (2) the test strategies based on physico-chemical behaviour of adhesives, (3) modelling migration/exposure from adhesives, (4) providing guidelines to integrate the risk-assessment approach into the daily life of companies, (5) the feasibility of applying the toxicological approach from the European Union BIOSAFEPAPER project, and (6) extensive training/education to small and medium-sized enterprises (SMEs) and large dissemination for general adoption of the concept in Europe.

  9. St. Louis Area Earthquake Hazards Mapping Project - December 2008-June 2009 Progress Report

    USGS Publications Warehouse

    Williams, R.A.; Bauer, R.A.; Boyd, O.S.; Chung, J.; Cramer, C.H.; Gaunt, D.A.; Hempen, G.L.; Hoffman, D.; McCallister, N.S.; Prewett, J.L.; Rogers, J.D.; Steckel, P.J.; Watkins, C.M.

    2009-01-01

    This report summarizes the mission, the project background, the participants, and the progress of the St. Louis Area Earthquake Hazards Mapping Project (SLAEHMP) for the period from December 2008 through June 2009. During this period, the SLAEHMP held five conference calls and two face-to-face meetings in St. Louis, participated in several earthquake awareness public meetings, held one outreach field trip for the business and government community, collected and compiled new borehole and digital elevation data from partners, and published a project summary.

  10. Western Kansas Migrant Health Project: 8th Annual Progress Report, 1971.

    ERIC Educational Resources Information Center

    Kansas State Dept. of Health, Topeka.

    The Western Kansas Migrant Health Project provides migrant families with such services as: (1) remedial schools and day care centers; (2) health education; (3) housing and sanitation; (4) nursing services; (5) medical and dental services; (6) hospital services; and (7) supplemental food programs. This 1971 annual progress report covers the…

  11. Contracts for field projects and supporting research on enhanced oil recovery. Progress review No. 89

    SciTech Connect

    1998-04-01

    Summaries are presented for the DOE contracts related to supported research for thermal recovery of petroleum, geoscience technology, and field demonstrations in high-priority reservoir classes. Data included for each project are: title, contract number, principal investigator, research organization, beginning date, expected completion date, amount of award, objectives of the research, and summary of technical progress.

  12. Hydrologic Resources Management Program and Underground Test Area Project FY 2000 Progress Report

    SciTech Connect

    Davisson, M L; Eaton, G F; Hakemi, N L; Hudson, G B; Hutcheon, I D; Lau, C A; Kersting, A B; Kenneally, J M; Moran, J E; Phinney, D L; Rose, T P; Smith, D K; Sylwester, E R; Wang, L; Williams, R; Zavarin, M

    2001-07-01

    This report highlights the results of FY 2000 technical studies conducted by the Analytical and Nuclear Chemistry Division (ANCD) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrology and Radionuclide Migration Program (HRMP) and Underground Test Area (UGTA) Project. This is the latest in a series of annual reports published by LLNL-ANCD to document recent investigations of radionuclide migration and transport processes at the Nevada Test Site (NTS). The HRMP is sponsored by Defense Programs (DP) at the U.S. Department of Energy, Nevada Operations Office (DOENV), and supports DP operations at the NTS through studies of radiochemical and hydrologic processes that are relevant to the DP mission. Other organizations that support the HRMP include Los Alamos National Laboratory (LANL), the U.S. Geological Survey (USGS), the Desert Research Institute (DRI) of the University of Nevada, the U.S. Environmental Protection Agency (EPS), and Bechtel Nevada (BN). The UGTA Project is sponsored by the Environmental Management (EM) program at DOENV; its goal is to determine the extent of radionuclide contamination in groundwater resulting from underground nuclear testing at the NTS. The project strategy follows guidelines set forth in a Federal Facilities Agreement and Consent Order between the U.S. Department of Energy, the U.S. Department of Defense, and the State of Nevada. Participating contractors include LLNL (both ANCD and the Energy and Environmental Sciences Directorate), LANL, USGS, DRI, BN, and IT Corporation (with subcontract support from Geotrans Inc.).

  13. Ground-water monitoring compliance projects for Hanford Site facilities: Annual progress report for 1987

    SciTech Connect

    Hall, S.H.

    1988-09-01

    This report describes progress during 1987 of five Hanford Site ground water monitoring projects. Four of these projects are being conducted according to regulations based on the federal Resource Conservation and Recovery Act of 1976 and the state Hazardous Waste Management Act. The fifth project is being conducted according to regulations based on the state Solid Waste Management Act. The five projects discussed herein are: 300 Area Process Trenches; 183-H Solar Evaporation Basins; 200 Areas Low-Level Burial Grounds; Nonradioactive Dangerous Waste Landfill; Solid Waste Landfill. For each of the projects, there are included, as applicable, discussions of monitoring well installations, water-table measurements, background and/or downgradient water quality and results of chemical analysis, and extent and rate of movement of contaminant plumes. 14 refs., 30 figs., 13 tabs.

  14. Progression in Investigative Work in Science: Procedural and Conceptual Knowledge in Science Project (the PACKS Project).

    ERIC Educational Resources Information Center

    Gott, Richard; And Others

    In investigative work, pupils encounter relatively open-ended tasks for which they have to devise their own solutions. Historically, the development of investigative work in the United Kingdom has come to the point where many schools are adopting it with some enthusiasm and with a degree of success. Progression has been largely defined by the…

  15. Advanced Coal Conversion Process Demonstration Project. Technical progress report, January 1, 1995--March 31, 1995

    SciTech Connect

    1996-06-01

    This detailed report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project. This U.S. Department of Energy (DOE) Clean Coal Technology Project demonstrates an advanced thermal coal upgrading process, coupled with physical cleaning techniques, that is designed to upgrade high-moisture, low-rank coals to high-quality, low-sulfur fuel. During this reporting period, the primary focus for the project was to expand market awareness and acceptability for the products and the technology. The use of covered hopper cars has been successful and marketing efforts have focused on this technique. Operational improvements are currently aimed at developing fines marketing systems, increasing throughput capacity, decreasing operation costs, and developing standardized continuous operator training. Testburns at industrial user sites were also conducted. A detailed process description; technical progress report including facility operations/plant production, facility testing, product testing, and testburn product; and process stability report are included. 3 figs., 8 tabs.

  16. Clinch River Breeder Reactor Plant Project. Summary edition. 1980 technical progress report, October 1979-September 1980

    SciTech Connect

    Not Available

    1980-01-01

    This technical progress report on the CRBRP Project describes the objectives, design decisions, and major accomplishments achieved in the planning, organizing, design, and execution of the Project during the period October 1, 1979, through September 30, 1980. It is a summary of the 1980 CRBRP Technical Progress Report, which was prepared by the Advanced Reactors Division of Westinghouse Electric Corporation, the Lead Reactor Manufacturer for the Clinch River Breeder Reactor Plant Project, in fulfillment of contract requirements with the United States Department of Energy. It includes inputs from the CRBRP Architect-Engineer (Burns and Roe, Inc.), from the Constructor (Stone and Webster Engineering Corporation), and from the supporting Reactor Manufacturers (Atomics International Division of the Energy Systems Group of Rockwell International Corporation, the Advanced Reactor Systems Department of General Electric Company, and the Advanced Reactors Division of Westinghouse Electric Corporation).

  17. Monitoring the Migrations of Wild Snake River Spring/Summer Chinook Salmon Smolts, 1994-1995 Progress (Annual) Report.

    SciTech Connect

    Achord, Stephen

    1996-09-01

    We PIT tagged wild spring/summer chinook-salmon parr in the Snake River Basin in 1994 and subsequently monitored these fish during their smolt migration through Lower Granite, Little Goose, Lower Monumental, McNary, John Day, and Bonneville Darns during spring, summer, and fall 1995. This report details our findings. The goals of this study are to (1) characterize the migration timing of different wild stocks of Snake River spring/summer chinook salmon smolts at dams on the Snake and Columbia Rivers, (2) determine if consistent patterns are apparent, and (3) determine what environmental factors influence migration timing.

  18. Environment, safety and health progress assessment of the Fernald Environmental Management Project (FEMP)

    SciTech Connect

    Not Available

    1991-11-01

    This report documents the results of the Environment, Safety, and Health (ES&H) Progress Assessment of the Fernald Environmental Management Project (FEMP), Fernald, Ohio, conducted from October 15 through October 25, 1991. The Secretary of Energy directed that small, focused, ES&H Progress Assessments be performed as part of the continuing effort to institutionalize line management accountability and the self-assessment process in the areas of ES&H. The FEMP assessment is the pilot assessment for this new program. The objectives for the FEMP ES&H Progress Assessment were to assess: (1) how the FEMP has progressed since the 1989 Tiger Assessment; (2) how effectively the FEMP has corrected specific deficiencies and associated root causes identified by that team; and (3) whether the current organization, resources, and systems are sufficient to proactively manage ES&H issues.

  19. Project SafeFoodPack Design: case study "indirect migration from paper and boards".

    PubMed

    Nguyen, Phuong-Mai; Julien, Jean Mario; Breysse, Colette; Lyathaud, Cédric; Thébault, Jacques; Vitrac, Olivier

    2017-04-04

    Migration due to indirect contact with packaging caused several major sanitary crises, including the spread contamination of dry food by mineral oils and printing ink constituents from cardboard. The issues are still not fully resolved because the mechanisms have been insufficiently described and the relationship between design, the contamination level, the type of contaminant, the conditions of storage (time and temperature) are poorly understood. This study proposes a forensic analysis of these phenomena, when food is separated from cardboard by a plastic layer. Practical relationships and advances simulation scenarios were devised and validated against the long-term migration between 20 °C and 60 °C of 15 substances. They were chosen to be representative of main contaminants of cardboard: aliphatic and aromatic mineral oils, photoinitiators and plasticizers. Data were summarized as iso-contamination curves and iso-contamination times up to two years. Simple rules are illustrated to extrapolate presented results to arbitrary conditions in order to identify critical substances, to estimate the plastic film thickness to keep the contamination within acceptable limits. Recommendations for risk management of contamination routes without contact are finally drafted.

  20. Environmentally conscious manufacturing & technology access project: Final technical progress report, April 1, 1994--September 30, 1996

    SciTech Connect

    1997-05-01

    This final report is being submitted in fulfillment of the management obligations associated with the TRP/DOE grant which funded the Environmentally Conscious Manufacturing & Technology Access (ECM) Project. A {open_quotes}Federal Assistance Project Status Report{close_quotes} is also being submitted with this form. This report will elaborate on the successful completion of this project in achieving and in most cases exceeding its programmatic goals and fulfilling it statutory financial match obligation. A review of the Year 1 {open_quotes}Technical Progress Report{close_quotes} and the Quarterly Reports filed during the project period, clearly portray that, in all substantive areas, the Environmentally Conscious Manufacturing & Technology Access Project (ECM Project) achieved or exceeded its goals. The success of the Project is largely due to the tremendous support provided by the Center for Technology Transfer (CTT) and the Maine Metal Products Association (MMPA). Both organizations provided extensive administrative and financial support and were instrumental in promoting the work of the project within the metals industry. The programmatic oversight provided by the industry Steering Committee and the broad partnership represented on the Board of Advisors were invaluable in developing, promoting and implementing the work of the ECM Project.

  1. Low-Cost Solar Array Project. Progress report 14, August 1979-December 1979 and proceedings of the 14th Project Integration Meeting

    SciTech Connect

    Not Available

    1980-01-01

    Progress made by the Low-Cost Solar Array Project during the period August through November 1979, is described. Progress on project analysis and integration; technology development in silicon material, large-area sheet silicon, and encapsulation; production process and equipment development; engineering, and operations, and the steps taken to integrate these efforts are detailed. A report on the Project Integration Meeting held December 5-6, 1979, including copies of the visual materials used, is presented.

  2. Hydrology/Radionuclide Migration Program and related research activities; FY 1986 progress report, October 1, 1985--September 30, 1986

    SciTech Connect

    Jones, M.A.

    1992-02-01

    This report presents the results of technical studies conducted under the Hydrology/Radionuclide Migration Program (HRMP) at the Nevada Test Site (NTS) for the period of October 1, 1985 through September 30, 1986. The HRMP was initiated in 1973 as the Radionuclide Migration Program to study and better understand the hydrologic systems of the NTS and potential movement and rates of movement of radionuclides and other contaminants injected into these systems by underground nuclear testing.

  3. Project Progress

    SciTech Connect

    William F. Morgan, Ph.D., D.Sc.

    2006-09-11

    The proposed study investigates the effect of low dose and low dose rate radiation exposure (X-rays) on induced genomic instability and the adaptive response, including the molecular mechanisms for these phenomena. The proposed studies will utilize human cell lines containing a stably integrated plasmid that can be caused by certain kinds of mutational insults to recombine to express the green fluorescent proteins, GFP. The study will use this cell line with the fluorescent plasmid recombination reporter system in a direct study of the effects of 1, 2.5, 5, 7.5, 10, 100 and 500 rads acute X-irradiation and the same doses delivered by protraction at 1 rad or 0.01 rad per minute. This system will be used to provide a quantitative measure of the kinetics of genomic instability in colonies of cells exposed to low dose/dose rate, as well as to examine the adaptive response. The study will also apply micro array technology to investigate the molecular mechanisms underlying induced instability and adaptive effects.

  4. Monarch Migration.

    ERIC Educational Resources Information Center

    Williamson, Brad; Taylor, Orley

    1996-01-01

    Describes the Monarch Watch program that tracks the migration of the monarch butterfly. Presents activities that introduce students to research and international collaboration between students and researchers. Familiarizes students with monarchs, stimulates their interest, and helps them generate questions that can lead to good research projects.…

  5. Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via activating the Akt pathway.

    PubMed

    Zheng, Dong; Chen, Ziang; Chen, Jingfu; Zhuang, Xiaomin; Feng, Jianqiang; Li, Juan

    2016-10-01

    Hydrogen sulfide (H2S), regarded as the third gaseous transmitter, mediates and induces various biological effects. The present study investigated the effects of H2S on multiple myeloma cell progression via amplifying the activation of Akt pathway in multiple myeloma cells. The level of H2S produced in multiple myeloma (MM) patients and healthy subjects was measured using enzyme-linked immunosorbent assay (ELISA). MM cells were treated with 500 µmol/l NaHS (a donor of H2S) for 24 h. The expression levels of phosphorylated-Akt (p-Akt), Bcl-2 and caspase-3 were measured by western blot assay. Cell viability was detected by Cell Counting Kit 8 (CCK-8). The cell cycle was analyzed by flow cytometry. Our results show that the concentration of H2S was higher in MM patients and that it increased in parallel with disease progression. Treating MM cells with 500 µmol/l NaHS for 24 h markedly increased the expression level of Bcl-2 and the activation of p-Akt, however, the expression level of caspase-3 was decreased, cell viability was increased, and cell cycle progression was accelerated in MM cells. NaHS also induced migration in MM cells in transwell migration assay. Furthermore, co-treatment of MM cells with 500 µmol/l NaHS and 50 µmol/l LY294002 for 24 h significantly overset these effects. In conclusion, our findings demonstrate that the Akt pathway contributes to NaHS-induced cell proliferation, migration and acceleration of cell cycle progression in MM cells.

  6. Progress of the Enhanced Hanford Single Shell Tank (SST) Integrity Project

    SciTech Connect

    Venetz, Theodore J.; Washenfelder, Dennis J.; Boomer, Kayle D.; Johnson, Jeremy M.; Castleberry, Jim L.

    2015-01-07

    To improve the understanding of the single-shell tanks (SSTs) integrity, Washington River Protection Solutions, LLC (WRPS), the USDOE Hanford Site tank contractor, developed an enhanced Single-Shell Tank Integrity Project (SSTIP) in 2009. An expert panel on SST integrity, consisting of various subject matters experts in industry and academia, was created to provide recommendations supporting the development of the project. This panel developed 33 recommendations in four main areas of interest: structural integrity, liner degradation, leak integrity and prevention, and mitigation of contamination migration. In late 2010, seventeen of these recommendations were used to develop the basis for the M-45-10-1 Change Package for the Hanford Federal Agreement and Compliance Order, which is also known as the Tri-Party Agreement.

  7. MHD Integrated Topping Cycle Project. Eighteenth quarterly technical progress report, November 1, 1991--January 31, 1992

    SciTech Connect

    Not Available

    1992-07-01

    This eighteenth quarterly technical progress report of the MHD Integrated Topping cycle Project presents the accomplishments during the period November 1, 1991 to January 31, 1992. The precombustor is fully assembled. Manufacturing of all slagging stage components has been completed. All cooling panels were welded in place and the panel/shell gap was filled with RTV. Final combustor assembly is in progress. The low pressure cooling subsystem (LPCS) was delivered to the CDIF. Second stage brazing issues were resolved. The construction of the two anode power cabinets was completed.

  8. Maunakea Spectroscopic Explorer: the status and progress of a major site redevelopment project

    NASA Astrophysics Data System (ADS)

    Murowinski, Rick; Simons, Douglas A.; McConnachie, Alan W.; Szeto, Kei

    2016-07-01

    The Maunakea Spectroscopic Explorer (MSE) project is a collaboration designing the largest non-ELT optical/NIR astronomical telescope to date. MSE is unique as a major astronomical facility since it involves the redevelopment of an existing facility, that of the Canada France Hawai`i Telescope (CFHT), with a newly expanded partnership. The project office is hosted at CFHT in Waimea HI, and includes new partners from Australia, China, India and Spain. The project is being developed by an international collaboration with design team membership distributed across four continents. In addition to a report on the progress and organization of design work, this paper describes the challenges of redeveloping a major astronomical site in Hawai`i. We discuss the Project Office and engineering work from the aspects of meeting the Science Requirements while satisfying the unique conditions imposed by redevelopment on Maunakea.

  9. Progress Report 16 for the period April-September 1980, and the proceedings of the 16th Project Integration Meeting

    SciTech Connect

    McDonald, R.R.

    1980-01-01

    Progress made by the Low-Cost Solar Array Project during the period April to September 1980, is reported in detail. Progress on project analysis and integration; technology development in silicon material, large-area silicon sheet and encapsulation; production process and equipment development; engineering, and operations is described. A report on, and copies of visual presentations made at, the Project Integration Meeting held September 24 and 25, 1980 are included.

  10. Controlled Hydrogen Fleet and Infrastructure Demonstration and Validation Project: Fall 2006 Progress Update

    SciTech Connect

    Wipke, K.; Welch, C.; Thomas, H.; Sprik, S.; Gronich, S.; Garbak, J.

    2006-10-01

    The U.S. Department of Energy (DOE) initiated the Controlled Hydrogen Fleet and Infrastructure Demonstration and Validation Project through a competitive solicitation process in 2003. The purpose of this project is to conduct an integrated field validation that simultaneously examines the performance of fuel cell vehicles and the supporting hydrogen infrastructure. Four industry teams have signed cooperative agreements with DOE and are supporting plans for more than 130 fuel cell vehicles and 20 hydrogen refueling stations over the 5-year project duration. This paper provides a status update covering the progress accomplished by the demonstration and validation project over the last six months; the first composite data products from the project were published in March 2006. The composite data products aggregate individual performance into a range that protects the intellectual property of the companies involved, while publicizing the progress the hydrogen and fuel cell industry is making as a whole relative to the program objectives and timeline. Updates to previously published composite data products, such as on-road fuel economy and vehicle/infrastructure safety, will be presented along with new composite data products, such as fuel cell stack efficiency and refueling behavior.

  11. Geothermal direct-heat utilization assistance. Quarterly project progress report, January--March 1996

    SciTech Connect

    1996-05-01

    This report summarizes geothermal technical assistance, R&D, and technology transfer activities of the Geo-Heat Center. It describes 95 contacts with parties during this period related to technical assistance with goethermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment, economics, and resources. Research activities are summarized on geothermal district heating system cost evaluation and silica waste utilization project. Outreach activities include publication of a geothermal direct use Bulletin, dissemination of information, goethermal library, technical papers and seminars, and progress monitor reports on geothermal resources and utilization.

  12. Hydrologic Resources Management Program and Underground Test Area Project FY 2006 Progress Report

    SciTech Connect

    Culham, H W; Eaton, G F; Genetti, V; Hu, Q; Kersting, A B; Lindvall, R E; Moran, J E; Blasiyh Nuno, G A; Powell, B A; Rose, T P; Singleton, M J; Williams, R W; Zavarin, M; Zhao, P

    2008-04-08

    This report describes FY 2006 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area Project (UGTA). These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The report is organized on a topical basis and contains four chapters that highlight technical work products produced by CBND. However, it is important to recognize that most of this work involves collaborative partnerships with the other HRMP and UGTA contract organizations. These groups include the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and National Security Technologies (NSTec). Chapter 1 is a summary of FY 2006 sampling efforts at near-field 'hot' wells at the NTS, and presents new chemical and isotopic data for groundwater samples from four near-field wells. These include PM-2 and U-20n PS 1DDh (CHESHIRE), UE-7ns (BOURBON), and U-19v PS No.1ds (ALMENDRO). Chapter 2 is a summary of the results of chemical and isotopic measurements of groundwater samples from three UGTA environmental monitoring wells. These wells are: ER-12-4 and U12S located in Area 12 on Rainier Mesa and

  13. Annual Progress Report Fish Research Project Oregon : Project title, Evaluation of Habitat Improvements -- John Day River.

    SciTech Connect

    Olsen, Erik A.

    1984-01-01

    This report summarizes data collected in 1983 to evaluate habitat improvements in Deer, Camp, and Clear creeks, tributaries of the John Day River. The studies are designed to evaluate changes in abundance of spring chinook and summer steelhead due to habitat improvement projects and to contrast fishery benefits with costs of construction and maintenance of each project. Structure types being evaluated are: (1) log weirs, rock weirs, log deflectors, and in stream boulders in Deer Creek; (2) log weirs in Camp Creek; and (3) log weir-boulder combinations and introduced spawning gravel in Clear Creek. Abundance of juvenile steelhead ranged from 16% to 119% higher in the improved (treatment) area than in the unimproved (control) area of Deer Creek. However, abundance of steelhead in Camp Creek was not significantly different between treatment and control areas. Chinook and steelhead abundance in Clear Creek was 50% and 25% lower, respectively in 1983, than the mean abundance estimated in three previous years. The age structure of steelhead was similar between treatment and control areas in Deer and Clear creeks. The treatment area in Camp Creek, however, had a higher percentage of age 2 and older steelhead than the control. Steelhead redd counts in Camp Creek were 36% lower in 1983 than the previous five year average. Steelhead redd counts in Deer Creek were not made in 1983 because of high streamflows. Chinook redds counted in Clear Creek were 64% lower than the five year average. Surface area, volume, cover, and spawning gravel were the same or higher than the corresponding control in each stream except in Deer Creek where there was less available cover and spawning gravel in sections with rock weirs and in those with log deflectors, respectively. Pool:riffle ratios ranged from 57:43 in sections in upper Clear Creek with log weirs to 9:91 in sections in Deer Creek with rock weirs. Smolt production following habitat improvements is estimated for each stream

  14. Progress on the FabrIc for Frontier Experiments project at Fermilab

    DOE PAGES

    Box, Dennis; Boyd, Joseph; Dykstra, Dave; ...

    2015-12-23

    The FabrIc for Frontier Experiments (FIFE) project is an ambitious, major-impact initiative within the Fermilab Scientific Computing Division designed to lead the computing model for Fermilab experiments. FIFE is a collaborative effort between experimenters and computing professionals to design and develop integrated computing models for experiments of varying needs and infrastructure. The major focus of the FIFE project is the development, deployment, and integration of Open Science Grid solutions for high throughput computing, data management, database access and collaboration within experiment. To accomplish this goal, FIFE has developed workflows that utilize Open Science Grid sites along with dedicated and commercialmore » cloud resources. The FIFE project has made significant progress integrating into experiment computing operations several services including new job submission services, software and reference data distribution through CVMFS repositories, flexible data transfer client, and access to opportunistic resources on the Open Science Grid. Hence, the progress with current experiments and plans for expansion with additional projects will be discussed. FIFE has taken a leading role in the definition of the computing model for Fermilab experiments, aided in the design of computing for experiments beyond Fermilab, and will continue to define the future direction of high throughput computing for future physics experiments worldwide« less

  15. Progress on the FabrIc for Frontier Experiments project at Fermilab

    SciTech Connect

    Box, Dennis; Boyd, Joseph; Dykstra, Dave; Garzoglio, Gabriele; Herner, Kenneth; Kirby, Michael; Kreymer, Arthur; Levshina, Tanya; Mhashilkar, Parag; Sharma, Neha

    2015-12-23

    The FabrIc for Frontier Experiments (FIFE) project is an ambitious, major-impact initiative within the Fermilab Scientific Computing Division designed to lead the computing model for Fermilab experiments. FIFE is a collaborative effort between experimenters and computing professionals to design and develop integrated computing models for experiments of varying needs and infrastructure. The major focus of the FIFE project is the development, deployment, and integration of Open Science Grid solutions for high throughput computing, data management, database access and collaboration within experiment. To accomplish this goal, FIFE has developed workflows that utilize Open Science Grid sites along with dedicated and commercial cloud resources. The FIFE project has made significant progress integrating into experiment computing operations several services including new job submission services, software and reference data distribution through CVMFS repositories, flexible data transfer client, and access to opportunistic resources on the Open Science Grid. Hence, the progress with current experiments and plans for expansion with additional projects will be discussed. FIFE has taken a leading role in the definition of the computing model for Fermilab experiments, aided in the design of computing for experiments beyond Fermilab, and will continue to define the future direction of high throughput computing for future physics experiments worldwide

  16. One System Integrated Project Team Progress in Coordinating Hanford Tank Farms and the Waste Treatment Plant

    SciTech Connect

    Skwarek, Raymond J.; Harp, Ben J.; Duncan, Garth M.

    2013-12-18

    The One System Integrated Project Team (IPT) was formed at the Hanford Site in late 2011 as a way to improve coordination and itegration between the Hanford Tank Waste Treatment and Immobilization Plant (WTP) and the Tank Operations Contractor (TOC) on interfaces between the two projects, and to eliminate duplication and exploit opportunities for synergy. The IPT is composed of jointly staffed groups that work on technical issues of mutal interest, front-end design and project definition, nuclear safety, plant engineering system integration, commissioning, planning and scheduling, and environmental, safety, health and quality (ESH&Q) areas. In the past year important progress has been made in a number of areas as the organization has matured and additional opportunities have been identified. Areas covered in this paper include: Support for development of the Office of Envirnmental Management (EM) framework document to progress the Office of River Protection's (ORP) River Protection Project (RPP) mission; Stewardship of the RPP flowsheet; Collaboration with Savannah River Site (SRS), Savannah River National Laboratory (SRNL), and Pacific Northwest National Laboratory (PNNL); Operations programs integration; and, Further development of the waste acceptance criteria.

  17. Great basin paleoenvironmental studies project; Technical progress report first quarter (year 2), June--August 1994

    SciTech Connect

    1994-10-01

    The paleobiotic and geomorphic records are being examined for the local and regional impact of past climates to assess Yucca Mountain`s suitability as a high-level nuclear waste repository. The project includes botanical, faunal, and geomorphic components that will be integrated to accomplish this goal Progress reports are presented for: Paleobotenical studies in the Great Basin; Paleofaunas studies in the Great Basin; Geomorphology studies in the Great Basin; and Transportation. The goal of the transportation project is to compare the results from three models (FESWMS-2DH, DAMBRK, and FLO-2D) that have been suggested as appropriate for evaluating flood flows on alluvial fans with the results obtained from the traditional one-dimensional, stochastic model used in previous research performed by DRI for the Yucca Mountain Project.

  18. Synthetic seismic monitoring using reverse-time migration and Kirchhoff migration for CO2 sequestration in Korea

    NASA Astrophysics Data System (ADS)

    Kim, W.; Kim, Y.; Min, D.; Oh, J.; Huh, C.; Kang, S.

    2012-12-01

    During last two decades, CO2 sequestration in the subsurface has been extensively studied and progressed as a direct tool to reduce CO2 emission. Commercial projects such as Sleipner, In Salah and Weyburn that inject more than one million tons of CO2 per year are operated actively as well as test projects such as Ketzin to study the behavior of CO2 and the monitoring techniques. Korea also began the CCS (CO2 capture and storage) project. One of the prospects for CO2 sequestration in Korea is the southwestern continental margin of Ulleung basin. To monitor the behavior of CO2 underground for the evaluation of stability and safety, several geophysical monitoring techniques should be applied. Among various geophysical monitoring techniques, seismic survey is considered as the most effective tool. To verify CO2 migration in the subsurface more effectively, seismic numerical simulation is an essential process. Furthermore, the efficiency of the seismic migration techniques should be investigated for various cases because numerical seismic simulation and migration test help us accurately interpret CO2 migration. In this study, we apply the reverse-time migration and Kirchhoff migration to synthetic seismic monitoring data generated for the simplified model based on the geological structures of Ulleung basin in Korea. Synthetic seismic monitoring data are generated for various cases of CO2 migration in the subsurface. From the seismic migration images, we can investigate CO2 diffusion patterns indirectly. From seismic monitoring simulation, it is noted that while the reverse-time migration generates clear subsurface images when subsurface structures are steeply dipping, Kirchhoff migration has an advantage in imaging horizontal-layered structures such as depositional sediments appearing in the continental shelf. The reverse-time migration and Kirchhoff migration present reliable subsurface images for the potential site characterized by stratigraphical traps. In case of

  19. Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition.

    PubMed

    Li, Juan; Davidson, Dominique; Martins Souza, Cleiton; Zhong, Ming-Chao; Wu, Ning; Park, Morag; Muller, William J; Veillette, André

    2015-12-01

    PTPN12 is a cytoplasmic protein tyrosine phosphatase (PTP) reported to be a tumor suppressor in breast cancer, through its capacity to dephosphorylate oncogenic receptor protein tyrosine kinases (PTKs), such as ErbB2. However, the precise molecular and cellular impact of PTPN12 deficiency in breast cancer progression remains to be fully clarified. Here, we addressed this issue by examining the effect of PTPN12 deficiency on breast cancer progression in vivo, in a mouse model of ErbB2-dependent breast cancer using a conditional PTPN12-deficient mouse. Our studies showed that lack of PTPN12 in breast epithelial cells accelerated breast cancer development and lung metastases in vivo. PTPN12-deficient breast cancer cells displayed enhanced tyrosine phosphorylation of the adaptor Cas, the adaptor paxillin, and the kinase Pyk2. They exhibited no detectable increase in ErbB2 tyrosine phosphorylation. PTPN12-deficient cells were more resistant to anoikis and had augmented migratory and invasive properties. Enhanced migration was corrected by inhibiting Pyk2. PTPN12-deficient breast cancer cells also acquired partial features of epithelial-to-mesenchymal transition (EMT), a feature of more aggressive forms of breast cancer. Hence, loss of PTPN12 promoted tumor progression in a mouse model of breast cancer, supporting the notion that PTPN12 is a tumor suppressor in human breast cancer. This function was related to the ability of PTPN12 to suppress cell survival, migration, invasiveness, and EMT and to inhibit tyrosine phosphorylation of Cas, Pyk2, and paxillin. These findings enhance our understanding of the role and mechanism of action of PTPN12 in the control of breast cancer progression.

  20. Personal genomes in progress: from the human genome project to the personal genome project.

    PubMed

    Lunshof, Jeantine E; Bobe, Jason; Aach, John; Angrist, Misha; Thakuria, Joseph V; Vorhaus, Daniel B; Hoehe, Margret R; Church, George M

    2010-01-01

    The cost of a diploid human genome sequence has dropped from about $70M to $2000 since 2007--even as the standards for redundancy have increased from 7x to 40x in order to improve call rates. Coupled with the low return on investment for common single-nucleotide polylmorphisms, this has caused a significant rise in interest in correlating genome sequences with comprehensive environmental and trait data (GET). The cost of electronic health records, imaging, and microbial, immunological, and behavioral data are also dropping quickly. Sharing such integrated GET datasets and their interpretations with a diversity of researchers and research subjects highlights the need for informed-consent models capable of addressing novel privacy and other issues, as well as for flexible data-sharing resources that make materials and data available with minimum restrictions on use. This article examines the Personal Genome Project's effort to develop a GET database as a public genomics resource broadly accessible to both researchers and research participants, while pursuing the highest standards in research ethics.

  1. Downregulation of ROS-FIG inhibits cell proliferation, colony‑formation, cell cycle progression, migration and invasion, while inducing apoptosis in intrahepatic cholangiocarcinoma cells.

    PubMed

    Deng, Gang; Hu, Chenghuan; Zhu, Lei; Huang, Feizhou; Huang, Wei; Xu, Hongbo; Nie, Wanpin

    2014-09-01

    Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer with poor responsiveness to existing drug therapies. Therefore, novel treatment strategies against ICC are required to improve survival. The aim of this study was to demonstrate the role of fused-in-glioblastoma-c-ros-oncogene1 (FIG-ROS) fusion gene in ICC. ROS was positively expressed in ICC tissues and HUCCT1 cells. Plasmids expressing ROS- and FIG-specific shRNAs were constructed and transfected into HUCCT1 cells. The results showed that single transfection of ROS- or FIG-specific shRNA inhibited HUCCT1 cell proliferation, colony formation, cell cycle progression, migration and invasion, while inducing apoptosis. Moreover, the co-inhibition of ROS- and FIG-specific shRNA exhibited stronger effects on HUCCT1 cell proliferation, apoptosis, colony formation, cell cycle progression, migration and invasion, when compared to single inhibition of ROS and FIG. Furthermore, findings of this study suggested that the AKT signaling pathway was involved in the ROS-FIG-mediated biological processes of HUCCT1 cells. In summary, the results suggest that FIG-ROS plays an oncogenic role in ICC. Additionally, ROS1-6290 and FIG-363 segments may become effective therapeutic targets for ICC harboring ROS-FIG fusion protein.

  2. Overexpression of Lin28 inhibits the proliferation, migration and cell cycle progression and induces apoptosis of BGC-823 gastric cancer cells.

    PubMed

    Song, Hu; Xu, Wei; Song, Jun; Liang, Yong; Fu, Wei; Zhu, Xiao-Cheng; Li, Chao; Peng, Jun-Sheng; Zheng, Jun-Nian

    2015-02-01

    Lin28 plays important roles in the development, maintenance of pluripotency and progression of various types of cancers. Lin28 represses the biogenesis of let-7 microRNAs and is implicated in both development and tumorigenesis. Oncogenic regulation of let-7 microRNAs has been demonstrated in several human malignancies, yet their correlation with Lin28 has not yet been studied in gastric cancer. Therefore, in the present study, we explored the possible mechanisms involved in the effects by Lin28 on the proliferation, migration, cell cycle arrest and apoptosis in gastric cancer cells via alteration of let-7 miRNA. The expression levels of Lin28 and let-7 were detected by real-time PCR in gastric cancer cell lines in vitro. Lin28 was overexpressed in the BGC-823 cells via lentiviral transfection, and let-7 expression was assessed. Cell proliferation and migration capabilities were investigated by MTT and Transwell assays, while cell cycle distribution and the apoptosis rate were detected using flow cytometry. The expression of Lin28 was moderately expressed in the GES cells while underexpressed in the BGC-823, SGC-7901 and HGC-27 cells. Let-7a miRNA was highly expressed in the GES, BGC-823, SGC-7901 and HGC-27 cells. Overexpression of Lin28 was inversely correlated with the downregulated expression of let-7a, and markedly suppressed the proliferation, migration, cell cycle progression and induced apoptosis in the BGC-823 cells. These findings demonstrated that overexpression of Lin28 can suppress the biological behavior of gastric cancer in vitro, and let-7 miRNA may play an important role in the process. We suggest that Lin28 may be a candidate predictor or an anticancer therapeutic target for gastric cancer patients.

  3. The Progress of Research Project for Magnetized Target Fusion in China

    NASA Astrophysics Data System (ADS)

    Yang, Xian-Jun

    2015-11-01

    The fusion of magnetized plasma called Magnetized Target Fusion (MTF) is a hot research area recently. It may significantly reduce the cost and size. Great progress has been achieved in past decades around the world. Five years ago, China initiated the MTF project and has gotten some progress as follows: 1. Verifying the feasibility of ignition of MTF by means of first principle and MHD simulation; 2. Generating the magnetic field over 1400 Tesla, which can be suppress the heat conduction from charged particles, deposit the energy of alpha particle to promote the ignition process, and produce the stable magnetized plasma for the target of ignition; 3. The imploding facility of FP-1 can put several Mega Joule energy to the solid liner of about ten gram in the range of microsecond risen time, while the simulating tool has been developed for design and analysis of the process; 4. The target of FRC can be generated by ``YG 1 facility'' while some simulating tools have be developed. Next five years, the above theoretical work and the experiments of MTF may be integrated to step up as the National project, which may make my term play an important lead role and be supposed to achieve farther progress in China. Supported by the National Natural Science Foundation of China under Grant No 11175028.

  4. The Umatilla Basin Natural Production Monitoring and Evaluation Project, 2008 Annual Progress Report.

    SciTech Connect

    Contor, Craig R.; Harris, Robin; King, Marty

    2009-06-10

    salmon (O. kisutch), and enhance summer steelhead (O. mykiss). The need for restoration began with agricultural development in the early 1900's that extirpated salmon and reduced steelhead runs (Bureau of Reclamation, BOR 1988). The most notable development was the construction and operation of Three Mile Falls Dam (TMD) and other irrigation projects which dewatered the Umatilla River during salmon migrations. CTUIR and ODFW developed the Umatilla Hatchery Master Plan to restore fisheries to the basin. The plan was completed in 1990 and included the following objectives which were updated in 1999: (1) Establish hatchery and natural runs of Chinook and coho salmon. (2) Enhance existing summer steelhead populations through a hatchery program. (3) Provide sustainable tribal and non-tribal harvest of salmon and steelhead. (4) Maintain the genetic characteristics of salmonids in the Umatilla River Basin. (5) Increase annual returns to Three Mile Falls Dam to 31,500 adult salmon and steelhead. In the past the M&E project conducted long-term monitoring activities as well as two and three-year projects that address special needs for adaptive management. Examples of these projects include adult passage evaluations, habitat assessment surveys (Contor et al. 1995, Contor et al. 1996, Contor et al. 1997, Contor et al. 1998), and genetic monitoring (Currens & Schreck 1995, Narum et al. 2004). The project's goal is to provide quality information to managers and researchers working to restore anadromous salmonids to the Umatilla River Basin. The status of completion of each of BPA's standardized work element was reported in 'Pisces'(March 2008) and is summarized.

  5. Heber geothermal binary demonstration project quarterly technical progress report, October 1, 1982--December 31, 1982

    SciTech Connect

    Lacy, R.G.; Allen, R.F.; Dixon, J.R.; Hsiao, W.P.; Liparidis, G.S.; Lombard, G.L.; Nelson, T.T.; Van De Mark, G.D.

    1983-05-01

    The purpose of this quarterly technical progress report is to document work completed on the nominal 65 Megawatt (Mwe gross) Heber Geothermal Binary Demonstration Project, located at Heber, California, during the period of October 1, 1982--December 31, 1982. The work was performed by San Diego Gas and Electric Company under the support and cooperation of the U.S. Department of Energy, the Electric Power Research Institute, the Imperial Irrigation District, the California Department of Water Resources, and the Southern California Edison Company. Topics covered in this quarterly report include progress made in the areas of Wells and Fluid Production and Injection Systems, Power Plant Design and Construction, Power Plant Demonstration, and Data Acquisition and Dissemination.

  6. Heber geothermal binary demonstration project quarterly technical progress report, July 1, 1981--September 30, 1981

    SciTech Connect

    Lacy, R.G.; Allen, R.F.; Alsup, R.A.; Liparidis, G.S.; Van De Mark, G.D.

    1983-08-01

    The purpose of this quarterly technical progress report is to document work completed on the nominal 65 Megawatt (Mwe gross) Heber Geothermal Binary Demonstration Project, located at Heber, California, during the period of July 1, 1981, through September 30, 1981. The work was performed by San Diego Gas and Electric Company under the support and cooperation of the US Department of Energy, the Electric Power Research Institute, the Imperial Irrigation District, the California Department of Water Resources, and the Southern California Edison Company. Topics covered in this quarterly report include progress made in the areas of Wells and Fluid production and Injection Systems, Power Plant Design and Construction, Power Plant Demonstration, and Data Acquisition and Dissemination.

  7. Colorado School of Mines Low Energy Nuclear Physics Project technical progress report

    SciTech Connect

    Cecil, F.E.

    1990-01-05

    This report summarizes the activity and accomplishments of the Colorado School of Mines Low Energy Nuclear Physics project during the calendar year 1989. Many of the projects which were anticipated in the original grant proposal have been completed. Among these completed projects we include of study of the radiative capture of low energy protons on {sup 6}Li, {sup 7}Li, {sup 9}Be, and {sup 11}B. Preliminary measurements of the branching ratios and yields of these reactions were reported in last year's Technical Progress Report. These measurements are now complete and have been used to extract the respective astrophysical S-factors and the corresponding thermonuclear reactivities. While not complete, progress has been made in some of the other originally proposed studies. Among these include a fairly extensive study of the interaction of low energy deuterons with {sup 6}Li and {sup 7}Li. In the course of this study we have made a solid observation of the Oppenheimer-Phillips effect in the D-{sup 6}Li system. Progress has been made in our study of the radiative capture of alpha particles by deuterons, {sup 6}Li, and {sup 7}Li but considerable work remains in these studies. In our earlier reports we noted the observation of d-d reactions during the bombardment of deuterated targets with energetic beams of protons, alpha particles, and other light-to-medium ions. We believe we now understand this phenomenon and feel it has some fairly significant consequences both for our studies and for those of other researchers. Our susceptibility to mob hysteria led us to invest a significant effort in cold nuclear fusion, both employing a fairly unique accelerator based approach at CSM and as one of the gamma ray diagnosticians on the Princeton Plasma Physics Laboratory's Cold Fusion Task Force.

  8. Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c.

    PubMed

    Wiegreffe, Christoph; Simon, Ruth; Peschkes, Katharina; Kling, Carolin; Strehle, Michael; Cheng, Jin; Srivatsa, Swathi; Liu, Pentao; Jenkins, Nancy A; Copeland, Neal G; Tarabykin, Victor; Britsch, Stefan

    2015-07-15

    During neocortical development, neurons undergo polarization, oriented migration, and layer-type-specific differentiation. The transcriptional programs underlying these processes are not completely understood. Here, we show that the transcription factor Bcl11a regulates polarity and migration of upper layer neurons. Bcl11a-deficient late-born neurons fail to correctly switch from multipolar to bipolar morphology, resulting in impaired radial migration. We show that the expression of Sema3c is increased in migrating Bcl11a-deficient neurons and that Bcl11a is a direct negative regulator of Sema3c transcription. In vivo gain-of-function and rescue experiments demonstrate that Sema3c is a major downstream effector of Bcl11a required for the cell polarity switch and for the migration of upper layer neurons. Our data uncover a novel Bcl11a/Sema3c-dependent regulatory pathway used by migrating cortical neurons.

  9. Geothermal direct-heat utilization assistance. Quarterly project progress report, July 1995--September 1995

    SciTech Connect

    Lienau, P.

    1995-12-01

    The report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the fourth quarter of FY-95. It describes 80 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment and resources. Research activities are summarized on low-temperature resource assessment, geothermal energy cost evaluation and marketing strategy for geothermal district heating. Outreach activities include the publication of a geothermal direct use Bulletin, dissemination of information, geothermal library, technical papers and seminars, and progress monitor reports on geothermal resources and utilization.

  10. Geothermal direct-heat utilization assistance: Quarterly project progress report, January--March 1995

    SciTech Connect

    1995-05-01

    The report summarizes geothermal activities of the Geo-Heat Center at Oregon Institute of Technology for the second quarter of FY-95. It describes 92 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, resources and equipment. Research activities are summarized on geothermal energy cost evaluation, low temperature resource assessment and ground-source heat pump case studies and utility programs. Outreach activities include the publication of a geothermal direct heat Bulletin, dissemination of information, geothermal library, and progress monitor reports on geothermal resources and utilization.

  11. Progress Report 18 for the Period February to July 1981 and Proceeidngs of the 18th Project Integration Meeting

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Progress in the low cost solar array project during the period February to July 1981 is reported. Included are: (1) project analysis and integration; (2) technology development in silicon material, large area silicon sheer and encapsulation; (3) process development; (4) engineering, and operations.

  12. 42 CFR 137.351 - Is a Self-Governance Tribe required to submit construction project progress and financial reports...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Roles of Self-Governance Tribe in Establishing and Implementing Construction Project Agreements § 137.351 Is a Self-Governance Tribe required to... Self-Governance Tribe must provide the Secretary with construction project progress and...

  13. Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasion

    PubMed Central

    Browne, Gillian; Taipaleenmäki, Hanna; Bishop, Nicole M.; Madasu, Sharath C.; Shaw, Leslie M.; van Wijnen, Andre J.; Stein, Janet L.; Stein, Gary S.; Lian, Jane B.

    2015-01-01

    Runx1 is a transcription factor essential for definitive hematopoiesis, and genetic abnormalities in Runx1 cause leukemia. Runx1 is functionally promiscuous and acts as either an oncogene or tumor suppressor gene in certain epithelial cancers. Recent evidence suggests that Runx1 is an important factor in breast cancer, however its role remains ambiguous. Here, we addressed whether Runx1 has a specific pathological role during breast cancer progression and show that Runx1 has an oncogenic function. We observed elevated Runx1 expression in a subset of human breast cancers. Furthermore, throughout the course of disease progression in a classical mouse model of breast cancer (i.e., the MMTV-PyMT transgenic model), Runx1 expression increases in the primary site (mammary gland) and is further upregulated in tumors and distal lung metastatic lesions. Ex vivo studies using tumor epithelial cells derived from these mice express significantly higher levels of Runx1 than normal mammary epithelial cells. The tumor cells exhibit increased rates of migration and invasion, indicative of an aggressive cancer phenotype. Inhibition of Runx1 expression using RNA interference significantly abrogates these cancer-relevant phenotypic characteristics. Importantly, our data establish that Runx1 contributes to murine mammary tumor development and malignancy and potentially represents a key disease-promoting and prognostic factor in human breast cancer progression and metastasis. PMID:25802202

  14. Projected Imbalances between Labor Supply and Labor Demand in the Caribbean Basin: Implications for Future Migration to the United States.

    ERIC Educational Resources Information Center

    Espenshade, Thomas J.

    This paper examines the economic push factors encouraging migration from the Caribbean Basin to the United States, as part of an assessment of the effectiveness of the Immigration Reform and Control Act of 1986. The basic assumption is that much of the migration is motivated by a desire to improve economic circumstances, and that the…

  15. Progress update of NASA's free-piston Stirling space power converter technology project

    NASA Astrophysics Data System (ADS)

    Dudenhoefer, James E.; Winter, Jerry M.; Alger, Donald

    1992-08-01

    A progress update is presented of the NASA LeRC Free-Piston Stirling Space Power Converter Technology Project. This work is being conducted under NASA's Civil Space Technology Initiative (CSTI). The goal of the CSTI High Capacity Power Element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA space initiatives. Efforts are focused upon increasing system power output and system thermal and electric energy conversion efficiency at least five fold over current SP-100 technology, and on achieving systems that are compatible with space nuclear reactors. This paper will discuss progress toward 1050 K Stirling Space Power Converters. Fabrication is nearly completed for the 1050 K Component Test Power Converter (CTPC); results of motoring tests of the cold end (525 K), are presented. The success of these and future designs is dependent upon supporting research and technology efforts including heat pipes, bearings, superalloy joining technologies, high efficiency alternators, life and reliability testing, and predictive methodologies. This paper will compare progress in significant areas of component development from the start of the program with the Space Power Development Engine (SPDE) to the present work on CTPC.

  16. Progress update of NASA's free-piston Stirling space power converter technology project

    NASA Technical Reports Server (NTRS)

    Dudenhoefer, James E.; Winter, Jerry M.; Alger, Donald

    1992-01-01

    A progress update is presented of the NASA LeRC Free-Piston Stirling Space Power Converter Technology Project. This work is being conducted under NASA's Civil Space Technology Initiative (CSTI). The goal of the CSTI High Capacity Power Element is to develop the technology base needed to meet the long duration, high capacity power requirements for future NASA space initiatives. Efforts are focused upon increasing system power output and system thermal and electric energy conversion efficiency at least five fold over current SP-100 technology, and on achieving systems that are compatible with space nuclear reactors. This paper will discuss progress toward 1050 K Stirling Space Power Converters. Fabrication is nearly completed for the 1050 K Component Test Power Converter (CTPC); results of motoring tests of the cold end (525 K), are presented. The success of these and future designs is dependent upon supporting research and technology efforts including heat pipes, bearings, superalloy joining technologies, high efficiency alternators, life and reliability testing, and predictive methodologies. This paper will compare progress in significant areas of component development from the start of the program with the Space Power Development Engine (SPDE) to the present work on CTPC.

  17. Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 83, quarter ending June 30, 1995

    SciTech Connect

    1996-08-01

    Summaries of 41 research projects on enhanced recovery are presented under the following sections: (1) chemical flooding; (2) gas displacement; (3) thermal recovery; (4) geoscience technology; (5) resource assessment technology; and (6) reservoir classes. Each presentation gives the title of the project, contract number, research facility, contract date, expected completion data, amount of the award, principal investigator, and DOE program manager, and describes the objectives of the project and a summary of the technical progress.

  18. Ceramic Technology Project, semiannual progress report for October 1993 through March 1994

    SciTech Connect

    Johnson, D.R.

    1994-09-01

    The Ceramic Technology Project was originally developed by the Department of Energy`s Office of Transportation Systems (OTS) in Conservation and Renewable Energy. Significant accomplishments in fabricating ceramic components for the Department of Energy (DOE), National Aeronautics and Space Administration (NASA), and Department of Defense (DoD) advanced heat engine programs have provided evidence that the operation of ceramic parts in high-temperature engine environments is feasible. An assessment of needs was completed, and a five-year project plan was developed with extensive input from private industry. In July 1990, the original plan was updated through the estimated completion of development in 1993. The original objective of the project was to develop the industrial technology base required for reliable ceramics for application in advanced automotive heat engines. During the course of the Ceramic Technology Project, remarkable progress has been made in the development of reliable structural ceramics. The direction of the Ceramic Technology Project is now shifting toward reducing the cost of ceramics to facilitate commercial introduction of ceramic components for near-term engine applications. In response to extensive input from industry, the plan is to extend the engine types which were previously supported (advanced gas turbine and low-heat-rejection diesel engines) to include near-term (5-10 years) applications in conventional automobile and diesel truck engines. To facilitate the rapid transfer of this technology to U.S. industry, the major portion of the work is being done in the ceramic industry, with technological support from government laboratories, other industrial laboratories, and universities. A systematic approach to reducing the cost of components is envisioned.

  19. miR-29a/b Enhances Cell Migration and Invasion in Nasopharyngeal Carcinoma Progression by Regulating SPARC and COL3A1 Gene Expression

    PubMed Central

    Deng, Ning; Guo, Tianyu; Cao, Yange; Yu, Ying; Wang, Xuejun; Zou, Bingcheng; Zhang, Songmei; Jing, Tao; Ling, Tao; Xie, Jun; Zhang, Qing

    2015-01-01

    Nasopharyngeal carcinoma (NPC) is a malignant tumor associated with a genetic predisposition, Epstein-Barr virus infection and chromosomal abnormalities. Recently, several miRNAs have been shown to target specific mRNAs to regulate NPC development and progression. However, the involvement of miRNAs in processes leading to NPC migration and invasion remains to be elucidated. We predicted that miR-29a/b are associated with dysregulated genes controlling NPC through an integrated interaction network of miRNAs and genes. miR-29a/b over-expression in NPC cell lines had no significant effect on proliferation, whereas miR-29b mildly increased the percentage of cells in the G1 phase with a concomitant decrease in the percentage of cells in S phase. Furthermore, we demonstrated that miR-29a/b might be responsible for increasing S18 cell migration and invasion, and only COL3A1 was identified as a direct target of miR-29b despite the fact that both SPARC and COL3A1 were inhibited by miR-29a/b over-expression. Meanwhile, SPARC proteins were increased in metastatic NPC tissue and are involved in NPC progression. Unexpectedly, we identified that miRNA-29b expression was elevated in the serum of NPC patients with a high risk of metastasis. The 5-year actuarial overall survival rates in NPC patients with high serum miR-29b expression was significantly shorter than those with low serum miR-29b expression; therefore, serum miR-29b expression could be a promising prognostic marker. PMID:25786138

  20. Umatilla River Fish Passage Operations Project : Annual Progress Report October 2007 - September 2008.

    SciTech Connect

    Bronson, James P.; Loffink, Ken; Duke, Bill

    2008-12-31

    Threemile Falls Dam (Threemile Dam), located near the town of Umatilla, is the major collection and counting point for adult salmonids returning to the Umatilla River. Returning salmon and steelhead were enumerated at Threemile Dam from June 7, 2007 to August 11, 2008. A total of 3,133 summer steelhead (Oncorhynchus mykiss); 1,487 adult, 1,067 jack, and 999 subjack fall Chinook (O. tshawytscha); 5,140 adult and 150 jack coho (O. kisutch); and 2,009 adult, 517 jack, and 128 subjack spring Chinook (O. tshawytscha) were counted. All fish were enumerated at the east bank facility. Of the fish counted, 1,442 summer steelhead and 88 adult and 84 jack spring Chinook were hauled upstream from Threemile Dam. There were 1,497 summer steelhead; 609 adult, 1,018 jack and 979 subjack fall Chinook; 5,036 adult and 144 jack coho; and 1,117 adult, 386 jack and 125 subjack spring Chinook either released at, or allowed to volitionally migrate past, Threemile Dam. Also, 110 summer steelhead; 878 adult and 43 jack fall Chinook; and 560 adult and 28 jack spring Chinook were collected as broodstock for the Umatilla River hatchery program. In addition, there were 241 adult and 15 jack spring Chinook collected at Threemile Dam for outplanting in the South Fork Walla Walla River and Mill Cr, a tributary of the mainstem Walla Walla River. The Westland Canal juvenile facility (Westland), located near the town of Echo at river mile (RM) 27, is the major collection point for out-migrating juvenile salmonids and steelhead kelts. The canal was open for 158 days between February 11, 2008 and July 18, 2008. During that period, fish were bypassed back to the river 150 days and were trapped 6 days. There were also 2 days when fish were directed into and held in the canal forebay between the time the bypass was closed and the trap opened. An estimated 64 pounds of fish were transported from the Westland trapping facility. Approximately 25.8% of the fish transported were salmonids. In addition, one

  1. Yucca Mountain Project - Argonne National Laboratory annual progress report, FY 1994

    SciTech Connect

    Bates, J.K.; Fortner, J.A.; Finn, P.A.; Wronkiewicz, D.J.; Hoh, J.C.; Emery, J.W.; Buck, E.C.; Wolf, S.F.

    1995-02-01

    This document reports on the work done by the Nuclear Waste Management Section of the Chemical Technology Division (CMT), Argonne National Laboratory, in the period October 1993-September 1994. Studies have been performed to evaluate the performance of nuclear waste glass and spent fuel samples under unsaturated conditions (low volume water contact) that are likely to exist in the Yucca Mountain environment being considered as a potential site for a high-level waste repository. Tests with simulated waste glasses have been in progress for over eight years and demonstrate that actinides from initially fresh glass surfaces will be released as a result of the spallation of reacted glass layers from the surface, as the small volume of water passes over the waste form. Studies are also underway to evaluate the performance of spent fuel samples and unirradiated UO{sub 2} in projected repository conditions. Tests with UO{sub 2} have been ongoing for nine years and show that the oxidation of UO{sub 2} occurs rapidly, and the resulting paragenetic sequence of secondary phases that form on the sample surface is similar to that observed in natural analogues. The reaction of spent fuel samples under conditions similar to those used with UO{sub 2} have been in progress for nearly two years, and the results suggest that spent fuel follows the same reaction progress as UO{sub 2}. The release of individual fission products and transuranic elements was not congruent, with the release being controlled by the formation of small particles or colloids that are suspended in solution and transported away from the waste form. The reaction progress depends on the composition of the spent fuel samples used and, likely, on the composition of the groundwater that contacts the waste form.

  2. Symmetries of migration related segments of all [001] coincidence site lattice tilt boundaries in (001) projections for all holohedral cubic materials

    SciTech Connect

    Moeck, Peter; York, Bryant W.; Browning, Nigel D.

    2014-09-11

    Utilizing bicrystallography in two dimensions (2D), the symmetries of migration related segments of Coincidence Site Lattice (CSL) boundaries are derived for projections along their [001] tilt axis in grain boundaries of crystalline materials that possess the holohedral point symmetry of the cubic system (i.e. m3m). These kinds of “edge-on” projections are typical for atomic resolution imaging of such tilt boundaries with Transmission Electron Microscopes (TEM). This fact facilitates the visual confirmation of our predictions by recently published Zcontrast scanning TEM investigations [H. Yang et al., Phil. Mag. 93 (2013) 1219] and many other TEM studies.

  3. MHD Integrated Topping Cycle Project. Sixteenth quarterly technical progress report, May 1991--July 1991

    SciTech Connect

    Not Available

    1992-03-01

    The Magnetohydrodynamics (MHD) Integrated Topping Cycle (ITC) Project represents the culmination of the proof-of-concept (POC) development stage in the US Department of Energy (DOE) program to advance MHD technology to early commercial development stage utility power applications. The project is a joint effort, combining the skills of three topping cycle component developers: TRW, Avco/TDS, and Westinghouse. TRW, the prime contractor and system integrator, is responsible for the 50 thermal megawatt (50 MW{sub t}) slagging coal combustion subsystem. Avco/TDS is responsible for the MHD channel subsystem (nozzle, channel, diffuser, and power conditioning circuits), and Westinghouse is responsible for the current consolidation subsystem. The ITC Project will advance the state-of-the-art in MHD power systems with the design, construction, and integrated testing of 50 MW{sub t} power train components which are prototypical of the equipment that will be used in an early commercial scale MHD utility retrofit. Long duration testing of the integrated power train at the Component Development and Integration Facility (CDIF) in Butte, Montana will be performed, so that by the early 1990`s, an engineering data base on the reliability, availability, maintainability and performance of the system will be available to allow scaleup of the prototypical designs to the next development level. This Sixteenth Quarterly Technical Progress Report covers the period May 1, 1991 to July 31, 1991.

  4. Hydrologic Resources Management Program and Underground Test Area Project FY2005 Progress Report

    SciTech Connect

    Eaton, G F; Genetti, V; Hu, Q; Hudson, G B; Kersting, A B; Lindvall, R E; Moran, J E; Nimz, G J; Ramon, E C; Rose, T P; Shuller, L; Williams, R W; Zavarin, M; Zhao, P

    2007-03-23

    This report describes FY 2005 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area Project (UGTA). These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The report is organized on a topical basis and contains five chapters that highlight technical work products produced by CBND. However, it is important to recognize that most of this work involves collaborative partnerships with the other HRMP and UGTA contract organizations. These groups include the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN).

  5. Hydrologic Resources Management Program and Underground Tests Area Project FY 2003 Progress Report

    SciTech Connect

    J., B C; F., E G; K., E B; L., F D; J., H L; Max, H; Bryant, H G; B., K A; E., M J; A., P G; P., R T; K., S D; F.B., T A; W., W R; Mavrik, Z; Pihong, Z

    2004-08-17

    This report describes FY 2003 technical studies conducted by the Chemical Biology and Nuclear Science Division (CBND) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area (UGTA) Project. These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work is directed toward the responsible management of the natural resources at the Nevada Test Site (NTS), enabling its continued use as a staging area for strategic operations in support of national security. UGTA-funded work emphasizes the development of an integrated set of groundwater flow and contaminant transport models to predict the extent of radionuclide migration from underground nuclear testing areas at the NTS. The present report is organized on a topical basis and contains five chapters that reflect the range of technical work performed by LLNL-CBND during FY 2003. Although we have emphasized investigations that were led by CBND, we also participated in a variety of collaborative studies with other UGTA and HRMP contract organizations including the Energy and Environment Directorate at LLNL (LLNL-E&E), Los Alamos National Laboratory (LANL), the Desert Research Institute (DRI), the U.S. Geological Survey (USGS), Stoller-Navarro Joint Venture (SNJV), and Bechtel Nevada (BN).

  6. Advanced Coal Conversion Process Demonstration Project. Final technical progress report, January 1, 1995--December 31, 1995

    SciTech Connect

    1997-05-01

    This report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project from January 1, 1995 through December 31, 1995. This project demonstrates an advanced, thermal, coal upgrading process, coupled with physical cleaning techniques, that is designed to upgrade high-moisture, low-rank coals to a high-quality, low-sulfur fuel, registered as the SynCoal Process. The coal is processed through three stages (two heating stages followed by an inert cooling stage) of vibrating fluidized bed reactors that remove chemically bound water, carboxyl groups, and volatile sulfur compounds. After thermal upgrading, the coal is put through a deep-bed stratifier cleaning process to separate the pyrite-rich ash from the coal. The SynCoal Process enhances low-rank, western coals, usually with a moisture content of 25 to 55 percent, sulfur content of 0.5 to 1.5 percent, and heating value of 5,5000 to 9,000 British thermal units per pound (Btu/lb), by producing a stable, upgraded, coal product with a moisture content as low as 1 percent, sulfur content as low as 0.3 percent, and heating value up to 12,000 Btu/lb. During this reporting period, the primary focus for the ACCP Demonstration Project team was to expand SynCoal market awareness and acceptability for both the products and the technology. The ACCP Project team continued to focus on improving the operation, developing commercial markets, and improving the SynCoal products as well as the product`s acceptance.

  7. The latest results on colloid associated radionuclide migration from the CFM Project, Grimsel Test Site (GTS, Switzerland)

    NASA Astrophysics Data System (ADS)

    Schaefer, T.; Blechschmidt, I.; Bouby, M.; Buechner, S.; Brendlé, J.; Geckeis, H.; Kupcik, T.; Goetz, R.; Hauser, W.; Heck, S.; Huber, F. M.; Lagos, M.; Martin, A. J.

    2013-12-01

    The influence of colloidal/nano-scale phases on the radionuclide (RNs) solubility and migration behavior is still one of the uncertainties in repository safety assessment [1]. Within the Colloid Formation and Migration (CFM) project at the Grimsel Test Site (GTS Switzerland) a huge geo-technical effort was taken to isolate hydraulically a shear-zone from the artificially introduced hydraulic gradient due to the tunnel construction. The construction is a combination of polymer resin impregnation of the tunnel surface and a steel torus to seal the tunnel surface. Natural outflow points of the MI shear zone were localized prior to the construction and sealed by surface packers. This design gives the opportunity to adjust the flow velocity in the fracture. After optimization of the experimental setup and injection procedure through a number of conservative tracer tests a license was granted in January 2012 by the Swiss regulator (BAG) to perform the first radionuclide tracer test under these low-flow conditions. The injection cocktail of 2.25L volume consisted of 101.4 × 2.5 mg/L montmorillonite clay colloids, whereas 8.9 × 0.4mg/L were present as synthetic montmorillonite with structural incorporated Ni. For details on the structural characterization of the Ni-montmorillonite phyllosilicate, see [2]. Beside the colloids and the conservative tracer Amino-G (1646 × 8ppb) the radioisotopes Na-22, Ba-133, Cs-137, Th-232, Np-237, Pu-242 and Am-243 were injected. The trivalent and tetravalent actinides were quantitatively associated with the colloids present as well as a part of the Cs, whereas Np(V) and Na are not bentonite colloid bond. For on-site colloid analysis a mobile Laser- Induced Breakdown Detection (LIBD) system similar to the one used in the CRR experiments [3] was transferred to Grimsel and installed in-line at the 'Pinkel' outlet to directly monitor the mobile colloid fraction throughout the experiment. The conservative tracer Amino-G was recovered

  8. Geothermal direct-heat utilization assistance. Quarterly project progress report, July--September 1997

    SciTech Connect

    1997-10-01

    This report summarizes geothermal technical assistance, R and D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the fourth quarter of FY-97 (July--September 1997). It describes 213 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include requests for general information including maps, geothermal heat pumps, resource and well data, space heating and cooling, greenhouses, acquaculture, equipment, district heating, resorts and spas, and industrial applications. Research activities include the completion of a Comprehensive Greenhouse Developer Package. Work accomplished on the revision of the Geothermal Direct Use Engineering and Design Guidebook are discussed. Outreach activities include the publication of the Quarterly Bulletin (Vol. 18, No. 3), dissemination of information mainly through mailings of publications, geothermal library acquisition and use, participation in workshops, short courses, and technical meetings by the staff, and progress monitor reports on geothermal activities.

  9. Progress in cavity and cryomodule design for the Project X linac

    SciTech Connect

    Champion, M.; Barbanotti, S.; Foley, M.; Ginsburg, S.; Gonin, I; Grimm, C.; Kerby, J.; Nagaitsev, S.; Nicol, T.; Peterson, T.; Ristori, L.; /Fermilab

    2011-03-01

    The continuous wave 3 GeV Project X Linac requires the development of two families of cavities and cryomodules at 325 and 650 MHz. The baseline design calls for three types of superconducting single-spoke resonators at 325 MHz having betas of 0.11, 0.22, and 0.42 and two types of superconducting five-cell elliptical cavities having betas of 0.61 and 0.9. These cavities shall accelerate a 1 mA H- beam initially and must support eventual operation at 4 mA. The electromagnetic and mechanical designs of the cavities are in progress and acquisition of prototypes is planned. The heat load to the cryogenic system is up to 25 W per cavity in the 650 MHz section, thus segmentation of the cryogenic system is a major issue in the cryomodule design. Designs for the two families of cryomodules are underway.

  10. MHD Integrated Topping Cycle Project. Seventeenth quarterly technical progress report, August 1, 1991--October 31, 1991

    SciTech Connect

    Not Available

    1992-07-01

    This seventeenth quarterly technical progress report of the MHD Integrated Topping Cycle Project presents the accomplishments during the period August 1, 1991 to October 31, 1991. Manufacturing of the prototypical combustor pressure shell has been completed including leak, proof, and assembly fit checking. Manufacturing of forty-five cooling panels was also completed including leak, proof, and flow testing. All precombustor internal components (combustion can baffle and swirl box) were received and checked, and integration of the components was initiated. A decision was made regarding the primary and backup designs for the 1A4 channel. The assembly of the channel related prototypical hardware continued. The cathode wall electrical wiring is now complete. The mechanical design of the diffuser has been completed.

  11. MHD Integrated Topping Cycle Project. Fourteenth quarterly technical progress report, November 1, 1990-- January 31, 1991

    SciTech Connect

    Not Available

    1992-02-01

    This fourteenth quarterly technical progress report of the MHD Integrated Topping Cycle Project presents the accomplishments during the period November 1, 1990 to January 31, 1991. Testing of the High Pressure Cooling Subsystem electrical isolator was completed. The PEEK material successfully passed the high temperature, high pressure duration tests (50 hours). The Combustion Subsystem drawings were CADAM released. The procurement process is in progress. An equipment specification and RFP were prepared for the new Low Pressure Cooling System (LPCS) and released for quotation. Work has been conducted on confirmation tests leading to final gas-side designs and studies to assist in channel fabrication.The final cathode gas-side design and the proposed gas-side designs of the anode and sidewall are presented. Anode confirmation tests and related analyses of anode wear mechanisms used in the selection of the proposed anode design are presented. Sidewall confirmation tests, which were used to select the proposed gas-side design, were conducted. The design for the full scale CDIF system was completed. A test program was initiated to investigate the practicality of using Avco current controls for current consolidation in the power takeoff (PTO) regions and to determine the cause of past current consolidation failures. Another important activity was the installation of 1A4-style coupons in the 1A1 channel. A description of the coupons and their location with 1A1 channel is presented herein.

  12. General-purpose heat source project and space nuclear safety and fuels program. Progress report

    SciTech Connect

    Maraman, W.J.

    1980-02-01

    Studies related to the use of /sup 238/PuO/sub 2/ in radioisotopic power systems carried out for the Advanced Nuclear Systems and Projects Division of LASL are presented. The three programs involved are: general-purpose heat source development; space nuclear safety; and fuels program. Three impact tests were conducted to evaluate the effects of a high temperature reentry pulse and the use of CBCF on impact performance. Additionally, two /sup 238/PuO/sub 2/ pellets were encapsulated in Ir-0.3% W for impact testing. Results of the clad development test and vent testing are noted. Results of the environmental tests are summarized. Progress on the Stirling isotope power systems test and the status of the improved MHW tests are indicated. The examination of the impact failure of the iridium shell of MHFT-65 at a fuel pass-through continued. A test plan was written for vibration testing of the assembled light-weight radioisotopic heater unit. Progress on fuel processing is reported.

  13. The creation and progress of the J Project in Eastern and Central Europe.

    PubMed

    Maródi, László

    2011-11-01

    Primary immunodeficiencies (PIDs) have now become recognized as a worldwide health problem. Rapid development of immunological and genetic technologies has led to the discovery of more than 200 PIDs and more than 150 disease-related genes. Progress in the field is expected to take a new turn after the introduction of new-generation sequencing technologies that will enable searches for currently unknown PID-related genes. By contrast, even with progress in molecular genetics, many patients remain ill and die early because of the lack of diagnostic or treatment facilities, or both. Thus, the gap between the knowledge accumulated and the appropriate management of patients with PIDs in everyday clinical practice has widened, necessitating PID awareness, particularly in countries with poor socioeconomic conditions. The J Project, established as a physician education and research collaboration program in Eastern and Central Europe, demonstrates how professional responsibility and long-term joint efforts can make a beneficial difference for patients with inborn errors of immunity.

  14. Plasminogen kringle 5-engineered glioma cells block migration of tumor-associated macrophages and suppress tumor vascularization and progression.

    PubMed

    Perri, Sabrina R; Nalbantoglu, Josephine; Annabi, Borhane; Koty, Zafiro; Lejeune, Laurence; François, Moïra; Di Falco, Marcos R; Béliveau, Richard; Galipeau, Jacques

    2005-09-15

    Angiostatin, a well-characterized angiostatic agent, is a proteolytic cleavage product of human plasminogen encompassing the first four kringle structures. The fifth kringle domain (K5) of human plasminogen is distinct from angiostatin and has been shown, on its own, to act as a potent endothelial cell inhibitor. We propose that tumor-targeted K5 cDNA expression may act as an effective therapeutic intervention as part of a cancer gene therapy strategy. In this study, we provide evidence that eukaryotically expressed His-tagged human K5 cDNA (hK5His) is exported extracellularly and maintains predicted disulfide bridging conformation in solution. Functionally, hK5His protein produced by retrovirally engineered human U87MG glioma cells suppresses in vitro migration of both human umbilical vein endothelial cells and human macrophages. Subcutaneous implantation of Matrigel-embedded hK5His-producing glioma cells in nonobese diabetic/severe combined immunodeficient mice reveals that hK5His induces a marked reduction in blood vessel formation and significantly suppresses the recruitment of tumor-infiltrating CD45+ Mac3+ Gr1- macrophages. Therapeutically, we show in a nude mouse orthotopic brain cancer model that tumor-targeted K5 expression is capable of effectively suppressing glioma growth and promotes significant long-term survival (>120 days) of test animals. These data suggest that plasminogen K5 acts as a novel two-pronged anticancer agent, mediating its inhibitory effect via its action on host-derived endothelial cells and tumor-associated macrophages, resulting in a potent, clinically relevant antitumor effect.

  15. Advanced Coal Conversion Process Demonstration Project. Technical progress report, January 1, 1993--December 31, 1993

    SciTech Connect

    1995-02-01

    This report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project from January 1, 1993, through December 31, 1993. This project demonstrates an advanced, thermal, coal drying process, coupled with physical cleaning techniques, that is designed to upgrade high-moisture, low- rank coals to a high-quality, low-sulfur fuel, registered as the SynCoal{reg_sign} process. The coal is processed through three stages (two heating stages followed by an inert cooling stage) of vibrating fluidized bed reactors that remove chemically bound water, carboxyl groups, and volatile sulfur compounds. After thermal processing, the coal is put through a deep-bed stratifier cleaning process to separate the pyrite-rich ash from the coal. Rosebud SynCoal Partnership`s ACCP Demonstration Facility entered Phase III, Demonstration Operation, in April 1992 and operated in an extended startup mode through August 10, 1993, when the facility became commercial. Rosebud SynCoal Partnership instituted an aggressive program to overcome startup obstacles and now focuses on supplying product coal to customers. Significant accomplishments in the history of the SynCoal{reg_sign} process development are shown in Appendix A.

  16. Advanced Coal Conversion Process Demonstration Project. Quarterly technical progress report, January 1, 1994--March 31, 1994

    SciTech Connect

    1996-02-01

    This report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project from January 1, 1994, through March 31, 1994. This project demonstrates an advanced, thermal, coal drying process, coupled with physical cleaning techniques, that is designed to upgrade high-moisture, low-rank coals to a high-quality, low-sulfur fuel, registered as the SynCoal{reg_sign} process. The coal is processed through three stages (two heating stages followed by an inert cooling stage) of vibrating fluidized bed reactors that remove chemically bound water, carboxyl groups, and volatile sulfur compounds. After thermal processing, the coal is put through a deep-bed stratifier cleaning process to separate the pyrite-rich ash from the coal. Rosebud SynCoal Partnership`s ACCP Demonstration Facility entered Phase III, Demonstration Operation, in April 1992 and operated in an extended startup mode through August 10, 1993, when the facility became commercial. Rosebud SynCoal Partnership instituted an aggressive program to overcome startup obstacles and now focuses on supplying product coal to customers. Significant accomplishments in the history of the SynCoal{reg_sign} process development are shown in Appendix A.

  17. [Advanced Coal Conversion Process Demonstration Project]. Technical progress report: April 1, 1992--June 30, 1992

    SciTech Connect

    Not Available

    1993-10-01

    This report describes the technical progress made on the Advanced Coal Conversion Process (ACCP) Demonstration Project from April 1, 1992, through June 30, 1992. This project demonstrates an advanced thermal coal drying process coupled with physical cleaning techniques designed to upgrade high-moisture, low-rank coals into a high-quality, low-sulfur fuel, registered as the SynCoal{reg_sign} process. The coal is processed through three stages (two heating stages followed by an inert cooling stage) of vibrating fluidized bed reactors that remove chemically bound water, carboxyl groups, and volatile sulfur compounds. After drying, the coal is put through a deep-bed stratifier cleaning process to separate the pyrite-rich ash from the coal. The SynCoal{reg_sign} process enhances low-rank, western coals, usually with a moisture content of 25 to 55 percent, sulfur content of 0.5 to 1.5 percent, and heating value of 5,500 to 9,000 British thermal units per pound (Btu/Ib), by producing a stable, upgraded coal product with a moisture content as low as 1 percent, sulfur content as low as 0.3 percent, and heating value up to 12,000 Btu/lb. The 45-ton-per-hour unit is located adjacent to a unit train loadout facility at Western Energy Company`s Rosebud coal mine near Colstrip, Montana. The demonstration plant is sized at about one-tenth the projected throughput of a multiple processing train commercial facility. The demonstration drying and cooling equipment is currently near commercial size.

  18. RCRA (Resource Conservation and Recovery Act) ground-water monitoring projects for Hanford facilities: Annual progress report for 1988

    SciTech Connect

    Fruland, R.M.; Lundgren, R.E.

    1989-04-01

    This report describes the progress during 1988 of 14 Hanford Site ground-water monitoring projects covering 16 hazardous waste facilities and 1 nonhazardous waste facility (the Solid Waste Landfill). Each of the projects is being conducted according to federal regulations based on the Resource Conservation and Recovery Act (RCRA) of 1976 and the State of Washington Administrative Code. 21 refs., 23 figs., 8 tabs.

  19. Contracts for field projects and supporting research on enhanced oil recovery. Progress review number 86, quarter ending March 31, 1996

    SciTech Connect

    1997-05-01

    Summaries are presented for 37 enhanced oil recovery contracts being supported by the Department of Energy. The projects are grouped into gas displacement methods, thermal recovery methods, geoscience technology, reservoir characterization, and field demonstrations in high-priority reservoir classes. Each summary includes the objectives of the project and a summary of the technical progress, as well as information on contract dates, size of award, principal investigator, and company or facility doing the research.

  20. Fluid flow, element migration, and petrotectonic evolution of the Early Mesozoic central Klamath Island arc, northwesternmost California. Progress report

    SciTech Connect

    Ernst, W.G.

    1992-12-11

    Investigations in the central Klamath Mountains (KM) have documented the presence of a polymetamorphosed suite of highly magnesian basaltic rocks, the Yellow Dog greenstones, in the Sawyers Bar (SB) terrane of the western Triassic and Paleozoic belt. The assemblage was laid down, altered and metasomatized during the hypothesized collapse of a Phillipine Sea-type back-arc basin which brought the westerly SB oceanic arc terrane into juxtaposition with the inboard, pre-existing Stuart Fork subduction complex, and more easterly KM terranes in an immature island arc setting. Supporting research has concentrated on elucidating the areal extent and structural/stratigraphic relations of these mafic/ultramafic Yellow Dog metavolcanic units, and has documented the insignificant degree of crustal contamination of the melts by associated terrigenous metasediments. The thermal structure and its evolution in the central KM evidently reflects surfaceward advective transport of magmatic energy derived from the partly fused downgoing oceanic slab, as well as hydrothermal fluid circulation. Clarification of the thermal evolution of this crust-constructional event in the immature basaltic island arc are the goals of the research now underway, emptying both field and geochemical methods. Continuing work is documenting the flow and P-T history of aqueous fluids through the evolving KM arc, utilizing electron microprobe and oxygen isotopic data. The authors have nearly finished a regional reconnaissance map showing the distribution of the lavas throughout the California part of the KM. Application of the terrane concept to the central KM has also been reevaluated in the light of regional petrotectonic relationships. Investigations of the regional and contact metamorphism/metasomatism of the SB metasedimentary pile are in progress.

  1. Are Substance Use Prevention Programs More Effective in Schools Making Adequate Yearly Progress? A Study of Project ALERT

    ERIC Educational Resources Information Center

    Clark, Heddy Kovach; Ringwalt, Chris L.; Shamblen, Stephen R.; Hanley, Sean M.; Flewelling, Robert L.

    2011-01-01

    This exploratory study sought to determine if a popular school-based drug prevention program might be effective in schools that are making adequate yearly progress (AYP). Thirty-four schools with grades 6 through 8 in 11 states were randomly assigned either to receive Project ALERT (n = 17) or to a control group (n = 17); of these, 10 intervention…

  2. Project LIFE--Language Improvement to Facilitate Education. (Technical Progress Report; Third Quarter; March 1, 1974-May 31, 1974).

    ERIC Educational Resources Information Center

    National Foundation for the Improvement of Education, Washington, DC.

    Reported is the third quarter, fiscal year 1974 (March 1, 1974-May 31, 1974) technical progress of Project LIFE (Language Improvement to Facilitate Education), toward developing an instructional system in which filmstrips in the areas of perceptual training, perceptual thinking, and language/reading are used to assist hearing impaired children in…

  3. Snake River Sockeye Salmon Captive Broodstock Program, Research Element : Project Progress Report, 2000 Annual Report.

    SciTech Connect

    Hebdon, J. Lance; Castillo, Jason; Kline, Paul A.

    2002-08-01

    On November 20, 1991, the National Marine Fisheries Service listed Snake River sockeye salmon Oncorhynchus nerka as endangered under the Endangered Species Act of 1973. In 1991, the Shoshone-Bannock Tribes and Idaho Department of Fish and Game initiated the Snake River Sockeye Salmon Sawtooth Valley Project to conserve and rebuild populations in Idaho. Restoration efforts are focusing on Redfish, Pettit, and Alturas lakes within the Sawtooth Valley. The first release of hatchery-produced juvenile sockeye salmon from the captive broodstock program occurred in 1994. The first anadromous adult returns from the captive broodstock program were recorded in 1999 when six jacks and one jill were captured at Idaho Department of Fish and Game's Sawtooth Fish Hatchery. In 2000, progeny from the captive broodstock program were released using four strategies: eyed-eggs were placed in Pettit Lake; age-0 presmolts were released to all three lakes in October; age-1 smolts were released to Redfish Lake Creek, and hatchery-produced adult sockeye salmon were released to Redfish and Alturas lakes for volitional spawning in September. Anadromous adult sockeye salmon were released to all three lakes. Total kokanee abundance in Redfish Lake was estimated at 10,268, which was the lowest abundance since 1991. Abundance of kokanee in Alturas Lake was estimated at 125,462, which was one of the highest values recorded since 1991. Abundance of kokanee in Pettit Lake was estimated at 40,599, which is the third highest value recorded since 1991. Upon the recommendation of the Stanley Basin Sockeye Technical Oversight Committee, the National Marine Fisheries Service reopened the kokanee fishery on Redfish Lake in 1995 in an attempt to reduce kokanee numbers. Anglers fished an estimated 3,063 hours and harvested approximately 67 kokanee during the 2000 season. Angler effort and harvest were also monitored on Alturas Lake during 2000. Effort on Alturas Lake was 5,190 hours, and harvest of kokanee

  4. St. Louis Area Earthquake Hazards Mapping Project - A Progress Report-November 2008

    USGS Publications Warehouse

    Karadeniz, D.; Rogers, J.D.; Williams, R.A.; Cramer, C.H.; Bauer, R.A.; Hoffman, D.; Chung, J.; Hempen, G.L.; Steckel, P.H.; Boyd, O.L.; Watkins, C.M.; McCallister, N.S.; Schweig, E.

    2009-01-01

    St. Louis has experienced minor earthquake damage at least 12 times in the past 200 years. Because of this history and its proximity to known active earthquake zones, the St. Louis Area Earthquake Hazards Mapping Project (SLAEHMP) is producing digital maps that show variability of earthquake hazards, including liquefaction and ground shaking, in the St. Louis area. The maps will be available free via the internet. Although not site specific enough to indicate the hazard at a house-by-house resolution, they can be customized by the user to show specific areas of interest, such as neighborhoods or transportation routes. Earthquakes currently cannot be predicted, but scientists can estimate how strongly the ground is likely to shake as the result of an earthquake. Earthquake hazard maps provide one way of conveying such estimates. The U.S. Geological Survey (USGS), which produces earthquake hazard maps for the Nation, is working with local partners to develop detailed maps for urban areas vulnerable to strong ground shaking. These partners, which along with the USGS comprise the SLAEHMP, include the Missouri University of Science and Technology-Rolla (Missouri S&T), Missouri Department of Natural Resources (MDNR), Illinois State Geological Survey (ISGS), Saint Louis University, Missouri State Emergency Management Agency, and URS Corporation. Preliminary hazard maps covering a test portion of the 29-quadrangle St. Louis study area have been produced and are currently being evaluated by the SLAEHMP. A USGS Fact Sheet summarizing this project was produced and almost 1000 copies have been distributed at several public outreach meetings and field trips that have featured the SLAEHMP (Williams and others, 2007). In addition, a USGS website focusing on the SLAEHMP, which provides links to project results and relevant earthquake hazard information, can be found at: http://earthquake.usgs.gov/regional/ceus/urban_map/st_louis/index.php. This progress report summarizes the

  5. Great Basin paleoenvironmental studies project; Technical progress report, second quarter, September--November, 1993

    SciTech Connect

    1993-12-31

    Progress is described in the four tasks associated with this project. Task 1, Paleobotanical studies in the Great Basin, has as its objective the reconstruction of the response of vegetation to climate in order to identify periods of mesic climate at Yucca Mountain during the last 20,000 to 50,000 years. Past extremes in infiltration rates are expected to serve as estimates of climate that may be expected during the next 10,000 years at Yucca Mtn. Task 2, Paleofaunas, will construct a history of Great Basin vertebrates that will provide empirical evidence of past environmental and climatic conditions. The objective of Task 3, Geomorphology, is to document the responses of surficial processes and landforms to the climatic changes documented by studies of packrat middens, pollen, and faunal distributions. The goal of Task 4, Transportation, is to compare the results from three models that have been suggested as appropriate for evaluating flood flows on alluvial fans with the results obtained from the traditional one-dimensional, stochastic model used in previous research for Yucca Mountain. This research looked at three alluvial fans with rail transportation alignments crossing them.

  6. Great Basin paleoenvironmental studies project; Technical progress report: Fourth quarter, March--May, 1994

    SciTech Connect

    1994-07-01

    Examination of the paleoenvironmental and geomorphic records to determine the local and regional impact of past climates will advance the assessment of Yucca Mountain`s suitability as a high-level nuclear waste repository. Paleobotanical studies will reconstruct the response of vegetation to climate change at the community and the organismal levels in order to identify periods of mesic climate at Yucca Mountain and the adjacent region during the last 20,000 to 50,000 years. Constructing a history of Great Basin vertebrates, particularly mammals, will provide empirical evidence of past environmental and climatic conditions within the Great Basin. The objective of the geomorphology component of the program is to document the responses of surficial processes and landforms to the climatic changes documented by studies of packrat middens, pollens, and faunal distributions. The goal of the transportation component is to compare the results from three models (FESWMS-2DH, DAMBRK, and FLO-2D) that have been suggested as appropriate for evaluating flood flows on alluvial fans with the results obtained from the traditional one-dimensional, stochastic model used in previous research for the Yucca Mountain Project. Progress on all these tasks is described.

  7. Low cost solar array project. Quarterly progress report, January-March 1980

    SciTech Connect

    Not Available

    1980-01-01

    The overall objective of the LSA Silicon Material Task is to establish a chemical process for producing silicon at a rate and rice commensurate with the production goals of the LSA project for solar-cell modules. As part of -- overall Silicon Material Task, Union Carbide developed the silane-silicon process and advanced the technology to the point where it has a definite potential for providing high-purity polysilicon on a commercial scale at a price of $14/kg by 1986 (1980 dollars). This work, completed under Phases I and II of the contract, provided a firm base for the Phase III program (initiated in April 1979) aimed at establishing the practicality of the process by pursuing the following specific objectives: (1) design, fabricate, install, and operate an Experimental Process System Development Unit (EPSDU) sized for 100 MT/Yr to obtain extensive performance data to establish the data base for the design of commercial facilities; (2) perform support research and development to provide an information base usable for the EPSDU and for technological design and economic analysis for potential scale-up of the process; and (3) perform iterative economic analyses of the estimated product cost for the production of semiconductor-grade silicon in a facility capably of producing 1000 MT/Yr. Progress is repoted in detail. (WHK)

  8. Geothermal direct-heat utilization assistance. Quarterly project progress report, October--December 1997

    SciTech Connect

    1997-01-01

    This report summarizes geothermal technical assistance, R and D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the first quarter of FY-98 (October--December 1997). It describes 216 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include requests for general information including maps and material for high school debates, and material on geothermal heat pumps, resource and well data, space heating and cooling, greenhouses, aquaculture, equipment, district heating, resorts and spas, industrial applications, electric power and snow melting. Research activities include work on model construction specifications of lineshaft submersible pumps and plate heat exchangers, a comprehensive aquaculture developer package and revisions to the Geothermal Direct Use Engineering and Design Guidebook. Outreach activities include the publication of the Quarterly Bulletin (Vol. 18, No. 4) which was devoted entirely to geothermal activities in South Dakota, dissemination of information mainly through mailings of publications, tours of local geothermal uses, geothermal library acquisition and use, participation in workshops, short courses and technical meetings by the staff, and progress monitor reports on geothermal activities.

  9. SETI prototype system for NASA's Sky Survey microwave observing project - A progress report

    NASA Technical Reports Server (NTRS)

    Klein, M. J.; Gulkis, S.; Wilck, H. C.

    1990-01-01

    Two complementary search strategies, a Targeted Search and a Sky Survey, are part of NASA's SETI microwave observing project scheduled to begin in October of 1992. The current progress in the development of hardware and software elements of the JPL Sky Survey data processing system are presented. While the Targeted Search stresses sensitivity allowing the detection of either continuous or pulsed signals over the 1-3 GHz frequency range, the Sky Survey gives up sensitivity to survey the 99 percent of the sky that is not covered by the Targeted Search. The Sky Survey spans a larger frequency range from 1-10 GHz. The two searches will deploy special-purpose digital signal processing equipment designed and built to automate the observing and data processing activities. A two-million channel digital wideband spectrum analyzer and a signal processor system will serve as a prototype for the SETI Sky Survey processor. The design will permit future expansion to meet the SETI requirement that the processor concurrently search for left and right circularly polarized signals.

  10. Federal assistance program. Quarterly project progress report, January 1998--March 1998

    SciTech Connect

    1998-04-01

    This report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the second quarter of FY-98-98 (January-March, 1998). It describes 268 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include requests for general information including maps and material for high school debates, and material on geothermal heat pumps, resource and well data, spacing heating and cooling, greenhouses, aquaculture, equipment, district heating, resorts and spas, industrial applications, electric power and snow melting. Research activities include work on model construction specifications for line shaft submersible pumps and plate heat exchangers and a comprehensive aquaculture developer package. The revised Geothermal Direct Use Engineering and Design Guidebooks was completed, published and is available for distribution. Outreach activities include the publication of the Quarterly Bulletin (Vol. 19, No. 1) which was devoted entirely to geothermal equipment, dissemination of information mainly through mailings of publications, tours of local geothermal uses, geothermal library acquisitions and use, participation in workshops, short courses and technical meetings by the staff, and progress monitor reports on geothermal activities.

  11. Project Management Plan/Progress Report UT/GTKS Training Program Development for Commercial Building Operators

    SciTech Connect

    None, None

    2013-03-31

    Universidad del Turabo (UT), in a collaborative effort with Global Turn Key Services, Inc. (GTKS), proposed to develop a training program and a commercialization plan for the development of Commercial Building Operators (CBOs). The CBOs will operate energy efficient buildings to help maintain existing buildings up to their optimal energy performance level, and ensure that net-zero-energy buildings continuously operate at design specifications, thus helping achieve progress towards meeting BTP Strategic Goals of creating technologies and design approaches that enable net-zero-energy buildings at low incremental costs by 2025. The proposed objectives were then: (1) Develop a Commercial Building Operator (CBO) training program and accreditation that will in turn provide a certification to participants recognized by Accreditation Boards such as the North American Board of Certified Energy Practitioners (NABCEP) and Leadership in Energy & Environmental Designs (LEED). (2) Develop and implement a commercialization and sustainability plan that details marketing, deployment, financial characterization, job placement, and other goals required for long-term sustainability of the project after the funding period. (3) After program development and deployment, provide potential candidates with the knowledge and skill sets to obtain employment in the commercial building green energy (net-zero-energy building) job market. The developed CBO training program will focus on providing skills for participants, such as displaced and unemployed workers, to enter the commercial building green energy (net-zeroenergy building) job market. This course was designed to allow a participant with minimal to no experience in commercial building green technology to obtain the required skill sets to enter the job market in as little as 12 weeks of intensive multi-faceted learning. After completion of the course, the CBO staff concluded the participant will meet minimum established accreditation

  12. The Agricultural Model Intercomparison and Improvement Project (AgMIP): Progress and Preliminary Results

    NASA Astrophysics Data System (ADS)

    Rosenzweig, C.

    2011-12-01

    The Agricultural Model Intercomparison and Improvement Project (AgMIP) is a distributed climate-scenario simulation exercise for historical model intercomparison and future climate change conditions with participation of multiple crop and agricultural trade modeling groups around the world. The goals of AgMIP are to improve substantially the characterization of risk of hunger and world food security due to climate change and to enhance adaptation capacity in both developing and developed countries. Recent progress and the current status of AgMIP will be presented, highlighting three areas of activity: preliminary results from crop pilot studies, outcomes from regional workshops, and emerging scientific challenges. AgMIP crop modeling efforts are being led by pilot studies, which have been established for wheat, maize, rice, and sugarcane. These crop-specific initiatives have proven instrumental in testing and contributing to AgMIP protocols, as well as creating preliminary results for aggregation and input to agricultural trade models. Regional workshops are being held to encourage collaborations and set research activities in motion for key agricultural areas. The first of these workshops was hosted by Embrapa and UNICAMP and held in Campinas, Brazil. Outcomes from this meeting have informed crop modeling research activities within South America, AgMIP protocols, and future regional workshops. Several scientific challenges have emerged and are currently being addressed by AgMIP researchers. Areas of particular interest include geospatial weather generation, ensemble methods for climate scenarios and crop models, spatial aggregation of field-scale yields to regional and global production, and characterization of future changes in climate variability.

  13. Low cost solar array project. Quarterly progress report, July-September 1980

    SciTech Connect

    Not Available

    1980-01-01

    The overall objective of the LSA Silicon Material Task is to establish a chemical process for producing silicon at a rate and price commensurate with the production goals of the LSA project for solar-cell modules. As part of the overall Silicon Material Task, Union Carbide developed the silane-silicon process and advanced the technology to the point where it has a definite potential for providing high-purity polysilicon on a commercial scale at a price of $14/kg by 1986 (1980 dollars). This process for preparing semiconductor-grade silicon in the EPSDU from metallurgical-grade (M-G) silicon is based on a well-integrated arrangement of purification steps that provides a cost-effective process system. The three basic steps entail converting M-G silicon to trichlorosilane, redistributing the trichlorosilane to produce silane, and thermally decomposing the silane to form amorphous silicon powder. The powder is then melted and the molten silicon is cast into polycrystalline silicon for subsequent use in fabricating solar cells. Progress is reported on the following tasks: (1) design, fabricate, install, and operate an Experimental Process System Development Unit (EPSDU) sized for 100 MT/Yr to obtain extensive performance data to establish the data base for the design of commercial facilities; (2) perform supporting research and development to provide an information base usable for the EPSDU and for technological design and economic analysis for potential scale-up of the process; and (3) perform iterative economic analyses of the estimated product cost for the product of semiconductor-grade silicon in a facility capable of producing 1000 MT/Yr. (WHK)

  14. Low-Cost Solar-Array Project. Quarterly progress report, April-June 1980

    SciTech Connect

    Not Available

    1980-01-01

    The overall objective of the LSA Silicon Material Task is to establish a chemical process for producing silicon at a rate and price commensurate with the production goals of the LSA project for solar-cell modules. As part of the overall Silicon Material Task, Union Carbide developed the silane-silicon process and advanced the technology to the point where it has a definite potential for providing high-purity polysilicon on a commercial scale at a price of $14/kg by 1986 (1980 dollars). This work, completed under Phases I and II of the contract, provided a firm base for the Phase III Program (initiated in April 1979) aimed at establishing the practicality of the process by pursuing the following specific objectives: (1) design, fabricate, install, and operate an Experimental Process System Development Unit (EPSDU) sized for 100 MT/yr to obtain extensive performance data to establish the data base for the design of commercial facilities; (2) perform support research and development to provide an information base usable for the EPSDU and for technological design and economic analysis for potential scale-up of the process; and (3) perform iterative economic analyses of the estimated product cost for the production of semiconductor-grade silicon in a facility capable of producing 1000 MT/yr. This process for preparing semiconductor-grade silicon in the EPSDU from metallurgical-grade (M-G) silicon is based on a well-integrated arrangement of purification steps that provides a cost-effective process system. The three basic steps entail converting M-G silicon to trichlorosilane, redistributing the trichlorosilane to produce silane, and thermally decomposing the silane to form amorphous silicon powder. The powder is then melted and the molten silicon is cast to polycrystalline for subsequent use in fabricating solar cells. Progress is reported in detail. (WHK)

  15. Tucannon Model Watershed 1997 Habitat Projects : Annual Progress Report Project Period: January 1, 1997 to March 31, 1998.

    SciTech Connect

    Bruegman, Terry; Nordheim, Debby

    1998-10-28

    The Tucannon Model Watershed 1997 habitat projects were designed to address critical limiting factors identified through the watershed assessment and Plan development. Construction elements were composed of bioengineering techniques designed to increase salmonid habitat complexity, insure stream bank and geomorphic stability, and reduce stream temperature and sediments in spawning gravels. Cooperation and agreement between landowners and resource agencies for restoring resource conditions has grown due to project success and is expected to continue for the benefit of all.

  16. Chernobyl Studies Project. Working Group 7.0, environmental transport and health effects. Progress report, February 1994

    SciTech Connect

    Hendrickson, S.M.

    1994-04-01

    The focus of the Chernobyl Studies Project has now turned to the issue of health effects from the Chernobyl accident. Currently, we are involved in and making progress on the case-control and co-hort studies of thyroid diseases among Belarussian children. Dosimetric aspects are a fundamental part of these studies. We are working to implement similar studies in Ukraine. A major part of the effort of these projects is supporting these studies, both by providing methods and applications of dose reconstruction and by providing support and equipment for the medical teams.

  17. Research project on CO{sub 2}-induced climate change. Annual progress report, March 1, 1994--February 28, 1995

    SciTech Connect

    Cess, R.D.; Hameed, S.

    1995-01-01

    This summarizes current progress in the research project at SUNY Stony Brook on CO2-induced climate change. Three tasks are described, corresponding to the task categories in the USDOE/PRC CAS cooperative project on climate change. Task 1, led by Dr. Robert Cess, concerns the intercomparison of CO2 related climatic warming in contemporary general circulation models. Task 2, directed by Dr. Sultan Hameed, looks at understanding the natural variability in climatic data and comparing its significant features between observations and model simulations. Task 3, also directed by Dr. Hameed focuses on analysis of historical climate data developed at the institute of Geography of the Chinese Academy of Sciences.

  18. The Silk Road Health Project: How Mobility and Migration Status Influence HIV Risks among Male Migrant Workers in Central Asia

    PubMed Central

    El-Bassel, Nabila; Gilbert, Louisa; Shaw, Stacey A.; Mergenova, Gaukhar; Terlikbayeva, Assel; Primbetova, Sholpan; Ma, Xin; Chang, Mingway; Ismayilova, Leyla; Hunt, Tim; West, Brooke; Wu, Elwin; Beyrer, Chris

    2016-01-01

    Objectives We examined whether mobility, migrant status, and risk environments are associated with sexually transmitted infections (STIs) and HIV risk behaviors (e.g. sex trading, multiple partners, and unprotected sex). Methods We used Respondent Driven Sampling (RDS) to recruit external male migrant market vendors from Kyrgyzstan, Uzbekistan, and Tajikistan as well internal migrant and non-migrant market vendors from Kazakhstan. We conducted multivariate logistic regressions to examine the effects of mobility combined with the interaction between mobility and migration status on STIs and sexual risk behaviors, when controlling for risk environment characteristics. Results Mobility was associated with increased risk for biologically-confirmed STIs, sex trading, and unprotected sex among non-migrants, but not among internal or external migrants. Condom use rates were low among all three groups, particularly external migrants. Risk environment factors of low-income status, debt, homelessness, and limited access to medical care were associated with unprotected sex among external migrants. Conclusion Study findings underscore the role mobility and risk environments play in shaping HIV/STI risks. They highlight the need to consider mobility in the context of migration status and other risk environment factors in developing effective prevention strategies for this population. PMID:26967159

  19. Project Integration Office for the electric and hybrid vehicle R and D program. Eighth progress report, March 1982

    SciTech Connect

    Not Available

    1982-04-19

    The Project Integration Office (PIO) was established to assist the US DOE with the direction and coordination of its multiple electric vehicle and hybrid electric vehicle research programs in order to get the maximum payoff from these research efforts. In addition, the PIO performs objective independent technical and economic studies, analyses and modeling, and maintains a technical information liaison service to facilitate information exchange between the program participants and industry. Progress in each of these activities is reported. (LCL)

  20. Projects at the Western Environmental Technology Office. Quarterly technical progress report, April 1--June 30, 1995

    SciTech Connect

    1995-08-01

    This report contains brief outlines of the multiple projects under the responsibility of the Western Environmental Technology Office in Butte Montana. These projects include biomass remediation, remediation of contaminated soils, mine waste technology, and several other types of remediation.

  1. Language Research in Progress: Report No. 7, January 1969; A Cross-Referenced List of Documented Language Research Projects Current April 1968 - November 1968.

    ERIC Educational Resources Information Center

    Hayes, Alfred S.; Vis, Joan

    This document is the seventh report in the Language Research in Progress (LRIP) series, and lists a wide variety of language-related research projects current between April 1968 and November 1968. Research projects terminated in the six months prior to publication are included as well. Approximately 250 projects in the U.S. and abroad are…

  2. Yucca Mountain site characteriztion project bibliography. Progress Report, 1994--1995

    SciTech Connect

    1996-08-01

    Following a reorganization of the Office of Civilian Radioactive Waste Management in 1990, the Yucca Mountain Project was renamed Yucca Mountain Site Characterization Project. The title of this bibliography was also changed to Yucca Mountain Site Characterization Project Bibliography. Prior to August 5, 1988, this project was called the Nevada Nuclear Waste Storage Investigations. This bibliography contains information on this ongoing project which was added to the Department of Energy`s Energy Science and Technology Database from January 1, 1994, through December 31, 1995. The bibliography is categorized by principal project participating organization. Participant-sponsored subcontractor reports, papers, and articles are included in the sponsoring organization`s list. Another section contains information about publications on the Energy Science and Technology database which were not sponsored by the project but have some relevance to it.

  3. First Year Progress Report on Project Open, Ona Junior High School, Cabell County, West Virginia, 1977-78 Project Year.

    ERIC Educational Resources Information Center

    Murwin, Scott; Murray, Michael

    As part of Project Open (see related documents listed below), unified arts and industrial arts curricula were developed and implemented at Ona Junior High School in West Virginia. The unified arts program combines the four subject areas of art, home economics, music, and industrial arts. It is a two-year required course for all seventh and eighth…

  4. Development of a Stochastic Inversion Tool To Optimize Agreement Between The Observed And Predicted Seismic Response To CO2 Injection/Migration in the Weyburn-Midale Project

    SciTech Connect

    Ramirez, A L; Hao, Y; White, D; Carle, S; Dyer, K; Yang, X; Mcnab, W; Foxall, W; Johnson, J

    2009-12-02

    During Phase 1 of the Weyburn Project (2000-2004), 4D reflection seismic data were used to map CO{sub 2} migration within the Midale reservoir, while an extensive fluid sampling program documented the geochemical evolution triggered by CO{sub 2}-brine-oil-mineral interactions. The aim of this task (3b.11) is to exploit these existing seismic and geochemical data sets, augmented by CO{sub 2}/H{sub 2}O injection and HC/H{sub 2}O production data toward optimizing the reservoir model and thereby improving site characterization and dependent predictions of long-term CO{sub 2} storage in the Weyburn-Midale reservoir. Our initial project activities have concentrated on developing a stochastic inversion method that will identify reservoir models that optimize agreement between the observed and predicted seismic response. This report describes the technical approach we have followed, the data that supports it, and associated implementation activities. The report fulfills deliverable D1 in the project's statement of work. Future deliverables will describe the development of the stochastic inversion tool that uses geochemical data to optimize the reservoir model.

  5. Determination and maintenance of DE minimis risk for migration of residual tritium (3H) from the 1969 Project Rulison nuclear test to nearby hydraulically fractured natural gas wells.

    PubMed

    Daniels, Jeffrey I; Chapman, Jenny B

    2013-05-01

    The Project Rulison underground nuclear test was a proof-of-concept experiment that was conducted under the Plowshare Program in 1969 in the Williams Fork Formation of the Piceance Basin in west-central Colorado. Today, commercial production of natural gas is possible from low permeability, natural gas bearing formations like that of the Williams Fork Formation using modern hydraulic fracturing techniques. With natural gas exploration and production active in the Project Rulison area, this human health risk assessment was performed in order to add a human health perspective for site stewardship. Tritium (H) is the radionuclide of concern with respect to potential induced migration from the test cavity leading to subsequent exposure during gas-flaring activities. This analysis assumes gas flaring would occur for up to 30 d and produce atmospheric H activity concentrations either as low as 2.2 × 10 Bq m (6 × 10 pCi m) from the minimum detectable activity concentration in produced water or as high as 20.7 Bq m (560 pCi m), which equals the highest atmospheric measurement reported during gas-flaring operations conducted at the time of Project Rulison. The lifetime morbidity (fatal and nonfatal) cancer risks calculated for adults (residents and workers) and children (residents) from inhalation and dermal exposures to such activity concentrations are all below 1 × 10 and considered de minimis. The implications for monitoring production water for conforming health-protective, risk-based action levels also are examined.

  6. Chernobyl Studies Project - working group 7.0 environmental transport and health effects. Progress report, October 1993--January 1994

    SciTech Connect

    Hendrickson, S.M.

    1994-03-01

    The DOE-funded Chernobyl Studies Project was begun as part of a cooperative agreement between the US and the former USSR, (quote) To develop jointly methods to project rapidly the health effects of any future reactor accident (quote). Most of the initial tasks for this project are completed or near completion. The focus has now turned primarily to the issue of health effects from the Chernobyl accident. Currently, we are extensively engaged in case-control and cohort studies of thyroid diseases among Belarussian children and in the Ukraine. A major part of the effort is providing methods and applications of dose reconstruction and providing support and equipment for the medical teams. This document contains reports on progress in the following task areas: Management; External Dose; Hydrological Transport; Chromosome Painting Dosimetry; Stochastic Effects; Thyroid Studies; and Leukemia Studies.

  7. High Performance Parallel Processing Project: Industrial computing initiative. Progress reports for fiscal year 1995

    SciTech Connect

    Koniges, A.

    1996-02-09

    This project is a package of 11 individual CRADA`s plus hardware. This innovative project established a three-year multi-party collaboration that is significantly accelerating the availability of commercial massively parallel processing computing software technology to U.S. government, academic, and industrial end-users. This report contains individual presentations from nine principal investigators along with overall program information.

  8. Florida "State" Migrant Health Project. Third Annual Progress Report, 1965-1966.

    ERIC Educational Resources Information Center

    Florida State Board of Health, Jacksonville.

    The Third Annual Report on the Florida Migrant Health Project covered migrant health activities engaged in by 14 counties for the period May 1, 1965, through April 30, 1966. The project was designed to develop a basic statewide program of health services for migrant farm workers and their dependents in Florida. Three of the 12 objectives included…

  9. The NEPAD e-Schools Demonstration Project: A Work in Progress. A Public Report

    ERIC Educational Resources Information Center

    Farrell, Glen; Isaacs, Shafika; Trucano, Michael

    2007-01-01

    The NEPAD e-Schools Initiative is a multi-country, multi-stakeholder, continental project to teach ICT skills to young Africans in primary and secondary schools and improve the provision of education in schools through the use of ICT applications and the Internet. The first phase of the Initiative is a "Demonstration Project"…

  10. A Progress Assessment of the School Health Education Project of Appalachian Maryland.

    ERIC Educational Resources Information Center

    Regional Education Service Agency of Appalachian Maryland, Cumberland.

    This document evaluates the effectiveness of a project on health education conducted in Appalachian Maryland. The emphasis of the project was on teaching children in the fifth grade about lung and respiratory system problems and their connection with smoking. This health education course was incorporated into their regular curriculum. Prior to…

  11. Projected progress in the engineering state-of-the-art. [for aerospace

    NASA Technical Reports Server (NTRS)

    Nicks, O. W.

    1978-01-01

    Projected advances in discipline areas associated with aerospace engineering are discussed. The areas examined are propulsion and power, materials and structures, aerothermodynamics, and electronics. Attention is directed to interdisciplinary relationships; one example would be the application of communications technology to the solution of propulsion problems. Examples involving projected technology changes are presented, and technology integration and societal effects are considered.

  12. The Columbia Classroom Environments Project...Fourth Progress Report, December 1971.

    ERIC Educational Resources Information Center

    Grannis, Joseph C.

    The Columbia Classroom Environments Project (CCEP) report discusses a number of questions about a set of dimensions of learning and development as well as the instruments the project was developing for the analysis of behavior in learning environments. Joseph C. Grannis examines The Argument, Assumptions, Definitions, Hypothesis; Rochelle Mayer…

  13. Asotin Creek Model Watershed 1997 Habitat Projects, 1997-1998 Annual Progress Report.

    SciTech Connect

    Johnson, B.J.

    1998-12-01

    The installation of fish and wildlife restoration projects on Asotin Creek completed in 1997 include: 11 in-stream habitat restoration projects, 3 reparian exclusion fences, 6 riparian fences, 14 sediment basin constructions, 54 sediment basin cleanouts, 1 multi-purpose pond construction, 1800 ft of terraces, and 1 three month water quality study. In-stream project objectives were to increase the number of large pools with complex fish habitat containing LWD, re-establish the steambank stability, and reduce in-stream temperatures. Most of the projects listed above were cost-share on private land with the landowners paying 50%-10% of the project costs and signing a ten-year maintenance agreement.

  14. Lake Roosevelt White Sturgeon Recovery Project : Annual Progress Report, January 2003 – March 2004.

    SciTech Connect

    Howell, Matthew D.; McLellan, Jason G.

    2009-07-15

    This report summarizes catch data collected from white sturgeon Acipenser transmontanus in Lake Roosevelt during limited setlining and gill netting activities in the fall of 2003, and documents progress toward development of a U.S. white sturgeon conservation aquaculture program for Lake Roosevelt. From 27-30 October, 42 overnight small mesh gill net sets were made between Marcus and Northport, WA for a total catch of 15 juvenile white sturgeon (275-488 mm FL). All sturgeon captured were of Canadian hatchery origin. These fish had been previously released as sub-yearlings into the Canadian portion (Keenleyside Reach) of the Transboundary Reach of the Columbia River during 2002 and 2003. Most sturgeon (n=14) were caught in the most upstream area sampled (Northport) in low velocity eddy areas. Five fish exhibited pectoral fin deformities (curled or stunted). Growth rates were less than for juvenile sturgeon captured in the Keenleyside Reach but condition factor was similar. Condition factor was also similar to that observed in juvenile sturgeon (ages 1-8) captured in the unimpounded Columbia River below Bonneville Dam between 1987-92. From 10-14 November, 28 overnight setline sets were made in the Roosevelt Reach between the confluence of the Spokane River and Marcus Island for a total catch of 17 white sturgeon (94-213 cm FL). Catch was greatest in the most upstream areas sampled, a distribution similar to that observed during a WDFW setline survey in Lake Roosevelt in 1998. The mean W{sub r} index of 110% for fish captured this year was higher than the mean W{sub r} of 91% for fish captured in 1998. Excellent fish condition hindered surgical examination of gonads as lipid deposits made the ventral body wall very thick and difficult to penetrate with available otoscope specula. Acoustic tags (Vemco model V16 coded pingers, 69 kHz, 48-month life expectancy) were internally applied to 15 fish for subsequent telemetry investigations of seasonal and reproductively

  15. Geothermal direct-heat utilization assistance. Quarterly project progress report, January--March 1994

    SciTech Connect

    Not Available

    1994-05-01

    The Geo-Heat Center provides technical assistance on geothermal direct heat applications to developers, consultants and the public which could include: data and information on low-temperature (< 1500 C) resources, space and district heating, geothermal heat pumps, greenhouses, aquaculture, industrial processes and other technologies. This assistance could include preliminary engineering feasibility studies, review of direct-use project plans, assistance in project material and equipment selection, analysis and solutions of project operating problems, and information on resources and utilization. The following are brief descriptions of technical assistance provided during the second quarter of the program.

  16. BX in situ oil shale project. Quarterly technical progress report, September 1-November 30, 1981

    SciTech Connect

    Dougan, P.M.

    1981-12-20

    September 1, 1981-November 30, 1981, was the fourth consecutive quarter of superheated steam injection at the BX In Situ Oil Shale Project. During the quarter, 117,520 barrels of water as steam were injected into project injection wells at an average wellhead temperature of 715/sup 0/F and an average wellhead pressure of 1378 PSIG. During the same period, 148,516 barrels of fluid were produced from the project production wells for a produced-to-injected fluid ratio of 1.26 to 1.0. Net oil production for the quarter was 169 barrels.

  17. Geothermal direct-heat utilization assistance. Quarterly project progress report, October--December 1993

    SciTech Connect

    Not Available

    1993-12-31

    This report consists of brief summaries of the activities of the Geo-Heat Center during the report period. Technical assistance was given to requests from 20 states in the following applications: space and district heating; geothermal heat pumps; greenhouses; aquaculture; industrial plants; electric power; resource/well; equipment; and resort/spa. Research and development activities progressed on (1) compilation of data on low-temperature resources and (2) evaluation of groundwater vs. ground-coupled heat pumps. Also summarized are technology transfer activities and geothermal progress monitoring activities.

  18. Contracts for field projects and supporting research on enhanced oil recovery and improved drilling technology. Progress review No. 34, quarter ending March 31, 1983

    SciTech Connect

    Linville, B.

    1983-07-01

    Progress achieved for the quarter ending March 1983 are presented for field projects and supporting research for the following: chemical flooding; carbon dioxide injection; and thermal/heavy oil. In addition, progress reports are presented for: resource assessment technology; extraction technology; environmental and safety; microbial enhanced oil recovery; oil recovered by gravity mining; improved drilling technology; and general supporting research. (ATT)

  19. 7 CFR 3402.23 - Documentation of progress on funded projects.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE FOOD AND AGRICULTURAL SCIENCES... of Fellows supported by any special international study or thesis/dissertation research allowance and... Research Information System (CRIS). The CRIS database contains narrative project information,...

  20. Progress and implications from the grazing lands Conservation Effects Assessment Project (CEAP) literature syntheses

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Conservation Effects Assessment Project (CEAP) is a multiagency effort to quantify scientifically the environmental outcomes of conservation practices used by private landowners. Two syntheses of the scientific literature are underway, which will document the environmental outcomes of conservati...

  1. PROGRESS REPORT ON HumRRO RESEARCH ON PROJECT 100,000

    DTIC Science & Technology

    Advisory Service. Preliminary findings are described, including certain background information concerning Project 100,000 personnel. Training factors, learning ability, literacy requirements, and on-the-job performance, are covered.

  2. Molten-Caustic-Leaching System Integration Project. Technical progress report, quarter ending March 27, 1992

    SciTech Connect

    Not Available

    1992-06-01

    The objective of this project is to modify an existing molten-caustic-leaching (MCL) system for coal upgrading so that it operates in an integrated continuous manner. The overall strategy consists of several tasks, but only a few are discussed here. Tasks discussed are: MCL circuit component testing (coal sample procurement), final circuit modifications for integrated operation, coal product handling/waste disposal (coal inventory disposal, MCL solid waste disposal), project management and control. (VC)

  3. Geothermal direct-heat utilization assistance. Quarterly project progress report, July 1996--September 1996. Federal Assistance Program

    SciTech Connect

    Lienau, P.

    1996-11-01

    This report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the fourth quarter of FY-96. It describes 152 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment, economics and resources. Research activities are summarized on greenhouse peaking. Outreach activities include the publication of a geothermal direct use Bulletin, dissemination of information, geothermal library, technical papers and seminars, and progress monitor reports on geothermal resources and utilization.

  4. Resource conservation and recovery act ground-water monitoring projects for Hanford facilities: Progress report, January 1--March 31, 1989

    SciTech Connect

    Smith, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-06-01

    This document describes the progress of 13 Hanford Site ground-water monitoring projects for the period January 1 to March 31, 1989. The work described in this document is conducted by the Pacific Northwest Laboratory under the management of Westinghouse Hanford Company for the US Department of Energy. Concentrations of ground-water constituents are compared to federal drinking water standards throughout this document for reference purposes. All drinking water supplied from the sampled aquifer meets regulatory standards for drinking water quality. 32 refs., 30 figs., 103 tabs.

  5. Toms Creek Integrated Gasification Combined Cycle Demonstration Project. Final quarterly technical progress report for the period ending March 31, 1993

    SciTech Connect

    Feher, G.

    1993-05-24

    This Quarterly Technical Progress Report for the period ending March 31, 1993 summarizes the work done to data by Tampella Power Corporation and Enviropower, Inc. on the integrated combined-cycle power plant project. Efforts were concentrated on the Toms Creek PDS (Preliminary Design and Studies). Tampella Power Corporation`s efforts were concentrated on the Toms Creek Preliminary Process Flow Diagram (PFD) and Piping and Instrument Diagrams (P&IDs). Tampella Power Corporation also prepared Heat and Material Balances (H&MBs) for different site-specific cases.

  6. Cell Migration

    PubMed Central

    Trepat, Xavier; Chen, Zaozao; Jacobson, Ken

    2015-01-01

    Cell migration is fundamental to establishing and maintaining the proper organization of multicellular organisms. Morphogenesis can be viewed as a consequence, in part, of cell locomotion, from large-scale migrations of epithelial sheets during gastrulation, to the movement of individual cells during development of the nervous system. In an adult organism, cell migration is essential for proper immune response, wound repair, and tissue homeostasis, while aberrant cell migration is found in various pathologies. Indeed, as our knowledge of migration increases, we can look forward to, for example, abating the spread of highly malignant cancer cells, retarding the invasion of white cells in the inflammatory process, or enhancing the healing of wounds. This article is organized in two main sections. The first section is devoted to the single-cell migrating in isolation such as occurs when leukocytes migrate during the immune response or when fibroblasts squeeze through connective tissue. The second section is devoted to cells collectively migrating as part of multicellular clusters or sheets. This second type of migration is prevalent in development, wound healing, and in some forms of cancer metastasis. PMID:23720251

  7. Research project on CO{sub 2}-induced climate change. Progress report, March 1, 1993--February 28, 1994

    SciTech Connect

    Cess, R.D.; Hameed, S.

    1994-03-01

    This summary of current progress in the research project at SUNY Stony Brook on CO{sub 2}-induced climate change is classified into three tasks corresponding to the task categories in the US DOE/PRC CAS cooperative project on climate change. Task 1, is concerned with intercomparison of CO{sub 2} related climatic warming in contemporary general circulation models. Task 2, aims at understanding the natural variability in climatic data and comparing its significant features between observations and model simulations. Task 3, focuses on analysis of historical climate data developed at the Institute of Geography of the Chinese Academy of Sciences. A summary of current research for all tasks is presented in this paper.

  8. Geothermal direct-heat utilization assistance: Federal assistance program. Quarterly project progress report, October--December 1995

    SciTech Connect

    1996-02-01

    The report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the first quarter of FY-96. It describes 90 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment and resources. Research activities are summarized on low-temperature resource assessment, geothermal district heating system cost evaluation and silica waste utilization project. Outreach activities include the publication of a geothermal direct use Bulletin, dissemination of information, geothermal library, technical papers and seminars, development of a webpage, and progress monitor reports on geothermal resources and utilization.

  9. Project Ideals: Curriculum and Instruction Practices for Continuous Learner Progress (Area G).

    ERIC Educational Resources Information Center

    Hass, Glen

    This pamphlet surveys the research and literature concerned with the effects of curriculum and instructional practices on pupil progress. Specific topics include (1) student grade acceleration and retardation, and elimination from school; (2) graded vs nongraded curriculum and school organization; (3) teaching and curriculum practices for…

  10. Reading Framework for the 1992 National Assessment of Educational Progress. NAEP Reading Consensus Project.

    ERIC Educational Resources Information Center

    Council of Chief State School Officers, Washington, DC.

    The Reading Framework for the 1992 National Assessment of Educational Progress (NAEP) contains the rationale for the aspects of reading assessed in 1992 and criteria for development of the assessment. Developed through a national consensus process as a part of an effort to move assessment forward, the framework presented in the booklet is more…

  11. Reading Framework for the National Assessment of Educational Progress: 1992-2000. NAEP Reading Consensus Project.

    ERIC Educational Resources Information Center

    Council of Chief State School Officers, Washington, DC.

    This booklet presents the Reading Framework for the 1992, 1994, 1998, and 2000 National Assessments of Educational Progress (NAEP), adopted by the National Assessment Governing Board (NAGB). The Framework contains the rationale for the aspects of reading assessed and criteria for development of the assessment. Developed through a national…

  12. Reading Framework for the 1992 and 1994 National Assessment of Educational Progress: NAEP Reading Consensus Project.

    ERIC Educational Resources Information Center

    Council of Chief State School Officers, Washington, DC.

    This booklet presents the Reading Framework for the 1992 and 1994 National Assessment of Educational Progress (NAEP), which contains the rationale for the aspects of reading assessed and the criteria for the development of the assessment. The booklet notes that the new reading assessment examines students' abilities to construct, extend, and…

  13. Reading Framework for the National Assessment of Educational Progress: 1992-1998. NAEP Reading Consensus Project.

    ERIC Educational Resources Information Center

    Council of Chief State School Officers, Washington, DC.

    This booklet presents the Reading Framework for the 1992, 1994, and 1998 National Assessment of Educational Progress (NAEP). Developed through a national consensus process as part of an effort to move assessment forward, the framework presented in the booklet is more consistent with contemporary knowledge about reading and more relevant to the…

  14. Civics Framework for the 2006 National Assessment of Educational Progress. NAEP Civics Project

    ERIC Educational Resources Information Center

    National Assessment Governing Board, 2007

    2007-01-01

    To gauge the civic knowledge and skills of the nation's 4th-, 8th-, and 12th-grade students, an assessment has been scheduled for 2006 by the National Assessment of Educational Progress (NAEP). This assessment will enable NAEP to report on trends in civics achievement from 1998 to 2006. The National Assessment Governing Board (NAGB), NAEP's…

  15. Piloting the AIM Project: Measuring Progress for Program Evaluation and Accountability.

    ERIC Educational Resources Information Center

    Mundie, Karen; Thompson, Debbie; Joyce, Michelle

    The AIM (Assessment, Instruction, Mastery) system is a performance-based assessment that was developed in Oregon. The AIM system was piloted by 83 volunteers and staff from 18 volunteer-based programs to assess the system's usefulness as a means of collecting and aggregating data on student progress in adult literacy and similar programs in…

  16. Astrocytes in Migration.

    PubMed

    Zhan, Jiang Shan; Gao, Kai; Chai, Rui Chao; Jia, Xi Hua; Luo, Dao Peng; Ge, Guo; Jiang, Yu Wu; Fung, Yin-Wan Wendy; Li, Lina; Yu, Albert Cheung Hoi

    2017-01-01

    Cell migration is a fundamental phenomenon that underlies tissue morphogenesis, wound healing, immune response, and cancer metastasis. Great progresses have been made in research methodologies, with cell migration identified as a highly orchestrated process. Brain is considered the most complex organ in the human body, containing many types of neural cells with astrocytes playing crucial roles in monitoring normal functions of the central nervous system. Astrocytes are mostly quiescent under normal physiological conditions in the adult brain but become migratory after injury. Under most known pathological conditions in the brain, spinal cord and retina, astrocytes are activated and become hypertrophic, hyperplastic, and up-regulating GFAP based on the grades of severity. These three observations are the hallmark in glia scar formation-astrogliosis. The reactivation process is initiated with structural changes involving cell process migration and ended with cell migration. Detailed mechanisms in astrocyte migration have not been studied extensively and remain largely unknown. Here, we therefore attempt to review the mechanisms in migration of astrocytes.

  17. A Progress Report on the Lincoln Near Earth Asteroid Research Project

    NASA Astrophysics Data System (ADS)

    Elowitz, R. M.; Stokes, G. H.; Bezpalko, M.; Blythe, M. S.; Evans, J. B.; Pearce, E. C.; Sayer, R. W.; Shelly, F. C.; Viggh, H. E. M.

    1999-12-01

    The Lincoln Near-Earth Asteroid Research (LINEAR) project is a MIT Lincoln Laboratory effort cooperatively sponsored by the United States Air Force Office of Scientific Research (AFOSR) and the National Aeronautics and Space Administration (NASA). The objective of the LINEAR project is to substantially contribute to the NASA goal of cataloging 90 larger than 1 km, within the next 10 years. Since March 1998, the LINEAR project has been hosted on a 1-meter diameter telescope located at the Lincoln Laboratory Experimental Test Site (ETS) on the White Sands Missile Range near Socorro, New Mexico. Beginning in October 1999, the LINEAR system added a second 1-meter telescope to routine operations, thus doubling the search capacity. Each telescope is equipped with a large format 2560x1960 back-illuminated frame-transfer CCD along with associated camera/processing elements developed by MIT Lincoln Laboratory for United States Air Force space surveillance applications. Since March of 1998, LINEAR has contributed 70 1999 the LINEAR project has discovered 66 Potentially Hazardous Asteroids (also referred to as PHAs), 20 Atens, 132 Apollos and 127 Amors type Near Earth asteroids. In addition, LINEAR has discovered 23 comets within the past year, and the first two asteroids with retrograde orbits that show no indication of cometary activity. Future plans for the LINEAR project include further automation of operations and processing enhancements that will increase the already impressive discovery rate of the LINEAR program.

  18. Progress in Projecting Solar Radiation at the Earth's Surface in Climate Models

    NASA Astrophysics Data System (ADS)

    Collins, W.; Fildier, B.; Feldman, D.

    2015-12-01

    Projecting changes in solar radiation at the Earth's surface in futureclimates is a critical input to forecast surface irradiance for solarenergy. We demonstrate the current state of the art using theensemble of opportunity assembled for the Coupled ModelIntercomparison Project (CMIP5) and the Fifth Assessment Report (AR5)of the Intergovernmental Panel on Climate Change (IPCC). The reliability of these projections depends upon the accuracy of theunderlying radiation codes, the fidelity of these codes to themeasured optical properties of key radiatively active atmosphericconstituents, and the realism of future projections of theseatmospheric constituents. These constituents include aerosols,clouds, water vapor, greenhouse gases that absorb near-infraredsunlight. Since the realism of future projections of anthropogenicaerosol species is contingent on the underlying scenario, we focus onthe other challenges in forecasting surface irradiance. Regarding accuracy, we demonstrate that current GCM shortwaveparameterizations often exhibit quite small errors relative tobenchmark radiative transfer codes. In addition, recent work hasbracketed the uncertainties in solar irradiance associated withcomplex cloud geometries. There is also an emerging consensus howcloud radiative effects will evolve in a warmer climate. However,there is evidence that current GCM codes still exhibit systematicerrors in the near-infrared water vapor bands, particularly for moistsub-tropical atmospheres. These errors will become more acute aswater vapor feedbacks, combined with global warming, increase thetotal precipitable water in the Earth's atmosphere.

  19. Changes in Gas Bubble Disease Signs and Survival of Migrating Juvenile Salmonids Experimentally Exposed to Supersaturated Gasses, 1995-1996 Progress Report.

    SciTech Connect

    Absolon, Randall F.

    1997-11-01

    Research conducted in 1996 to evaluate (1) changes in GBD signs in juvenile salmonids resulting from passage through turbine intakes and bypass systems, and (2) relative survival during migration through the lower Snake River for juvenile salmonids experimentally exposed to supersaturation of dissolved gas.

  20. The Human Genome Project and Mental Retardation: An Educational Program. Final Progress Report

    SciTech Connect

    Davis, Sharon

    1999-05-03

    The Arc, a national organization on mental retardation, conducted an educational program for members, many of whom have a family member with a genetic condition causing mental retardation. The project informed members about the Human Genome scientific efforts, conducted training regarding ethical, legal and social implications and involved members in issue discussions. Short reports and fact sheets on genetic and ELSI topics were disseminated to 2,200 of the Arc's leaders across the country and to other interested individuals. Materials produced by the project can e found on the Arc's web site, TheArc.org.

  1. HIFS VNL Monthly Progress Report Preparation for NDCX-II Project

    SciTech Connect

    Logan, Grant; Kwan, Joe; Barnard, John; Friedman, Alex; Gilson, Erik; Leitner, Matthaeus; Waldron, Will; Bieniosek, Frank

    2009-05-29

    In preparation for the project and for anticipated review in August, the HIFS-VNL hosted an NDCX-II Advisory Meeting at LBNL on May 27, 2009. A number of experts in accelerator physics, engineering, and construction were asked to visit for a full day, listen to presentations on the project, its goals, and its status, and to offer their advice on how best to proceed, what topics needed attention, and what technical options seemed most attractive to them. This was a productive meeting, and the Committee's comments will provide useful guidance.

  2. ERIP Project No. 670, Nevada Energy Control Systems, Inc.. Final techincal progress report

    SciTech Connect

    Kimber, D.J.

    1998-02-11

    In order to gauge the effectiveness of the ERIP Project No. 670, Nevada Energy Control Systems, Inc., Grant Number DE-FG01-96EE15670, the Statement of Work must be compared to the achievements by NECSI during the grant period. The following report reflects the aforementioned statement and is coordinated directly with it. The project goal is to gather data and test in order to validate earlier tests of energy savings,safety,reliability and practicality of the NECSI Evaporator Fan Controller in order to fully commercialize and market the product.

  3. Low cost solar array project. Quarterly progress report, January-March, 1981

    SciTech Connect

    Not Available

    1981-01-01

    The engineering design, fabrication, assembly, operation, economic analysis, and process support R and D for an Experimental Process System Development Unit (EPSDU) are presented. The civil construction work was completed and the mechanical bid package is in preparation. The electrical design effort is in progress. Parallel efforts which complement the mechanical design are the process flow diagrams and control instrumentation logic for startup operation and shutdown. These are in progress and will identify all process and utility streams, control systems, and flow logic. The data collection system takes the signals from the instrumentation, translates them into engineering units and finally develops a data report which summarizes all key performance parameters. Cleaning procedures have been established to assure a contamination-free product and inspection visits have been made to the fabricators of specialty equipment.

  4. [The Juniper Gardens Children's Project.] Final Progress Report for OEO Grant CG-8180.

    ERIC Educational Resources Information Center

    Juniper Gardens Children's Project, Kansas City, MO.

    Research and demonstration activities at the Juniper Gardens Children's Project at the University of Kansas involved studies in these areas: (1) an after school remedial classroom program, (2) inappropriate study behavior in class, and (3) demonstration activities which involved teacher and parent training. The effects of reinforcement…

  5. Assigning Inquiry: How Handouts for Research Assignments Guide Today's College Students. Project Information Literacy Progress Report

    ERIC Educational Resources Information Center

    Head, Alison J.; Eisenberg, Michael B.

    2010-01-01

    A report of findings from a content analysis of 191 course-related research assignment handouts distributed to undergraduates on 28 college campuses across the U.S., as part of Project Information Literacy. A majority of handouts in the sample emphasized standards about the mechanics of compiling college research papers, more so than guiding…

  6. Two Decades of JDAI: From Demonstration Project to National Standard. A Progress Report

    ERIC Educational Resources Information Center

    Mendel, Richard

    2009-01-01

    Launched in the 1990s by the Annie E. Casey Foundation as a five-site demonstration project, the Juvenile Detention Alternatives Initiative (JDAI) has steadily swept the country in recent years and is on track to become the standard of practice for how local justice systems nationwide handle the critical front end of the juvenile court process.…

  7. Project MEDICO; Model Experiment in Drug Indexing by Computer. First Progress Report.

    ERIC Educational Resources Information Center

    Artandi, Susan; Baxendale, Stanley

    This report describes Phase 1 of a research project with the over-all objective of exploring the applicability of automatic methods in the indexing of drug information appearing in English natural language text. Two major phases of the research have been completed: (1) development of the automatic indexing method and its implementation on the test…

  8. Alaska Broad Scale Orthoimagery and Elevation Mapping - Current Statewide Project Progress and Historic Work in Alaska

    NASA Astrophysics Data System (ADS)

    Heinrichs, T. A.; Broderson, D.; Johnson, A.; Slife, M.

    2014-12-01

    This presentation describes the overall program goals and current status of broad scale, statewide orthoimagery and digital elevation model (DEM) projects currently underway in Alaska. As context, it will also describe the history and successes of previous statewide Alaska mapping efforts over the preceding 75 years. A new statewide orthomosaic imagery baselayer at 1:24,000 NMAS accuracy (12.2-meters CE90) is nearing completion. The entire state (1.56 million square kilometers) has been imaged with the SPOT 5 satellite, and a 2.5-meter spatial resolution, multi-spectral, nearly cloud-free, pan-sharpened orthoimage will be produced by mid-2015. A second major project is collection of an improved accuracy DEM statewide. Airborne interferometric synthetic aperture radar (IfSAR) data has been collected for about half of the state of Alaska and completion of the rest of the state is anticipated within a few years. A 5-meter post spacing, 20-foot contour interval accuracy equivalent (3-meter vertical LE90) DEM and radar backscatter intensity image is being delivered. Historic projects to be described include the 1950's USGS Alaska topographic mapping program, one of the largest and most pioneering, challenging, and successful ever undertaken in North America. These historic and current mapping programs have served as both a baselayer framework and as feedstock for science for virtually every geologic, geophysical, and terrestrial natural science project in the state.

  9. Progress of the Photovoltaic Technology Incubator Project Towards an Enhanced U.S. Manufacturing Base: Preprint

    SciTech Connect

    Ullal, H.; Mitchell, R.; Keyes, B.; VanSant, K.; von Roedern, B.; Symko-Davies, M.; Kane, V.

    2011-07-01

    In this paper, we report on the major accomplishments of the U.S. Department of Energy's (DOE) Solar Energy Technologies Program (SETP) Photovoltaic (PV) Technology Incubator project. The Incubator project facilitates a company's transition from developing a solar cell or PV module prototype to pilot- and large-scale U.S. manufacturing. The project targets small businesses that have demonstrated proof-of-concept devices or processes in the laboratory. Their success supports U.S. Secretary of Energy Steven Chu's SunShot Initiative, which seeks to achieve PV technologies that are cost-competitive without subsidies at large scale with fossil-based energy sources by the end of this decade. The Incubator Project has enhanced U.S. PV manufacturing capacity and created more than 1200 clean energy jobs, resulting in an increase in American economic competitiveness. The investment raised to date by these PV Incubator companies as a result of DOE's $ 59 million investment totals nearly $ 1.3 billion.

  10. Lessons Learned: How College Students Seek Information in the Digital Age. Project Information Literacy Progress Report

    ERIC Educational Resources Information Center

    Head, Alison J.; Eisenberg, Michael B.

    2009-01-01

    A report of findings from 2,318 respondents to a survey carried out among college students on six campuses distributed across the U.S. in the spring of 2009, as part of Project Information Literacy. Respondents, while curious in the beginning stages of research, employed a consistent and predictable research strategy for finding information,…

  11. West Hackberry Tertiary Project. Quarterly technical progress report, January 1, 1996--March 31, 1996

    SciTech Connect

    Gillham, T.; Cerveny, B.; Turek, E.

    1996-04-10

    The goal of the West Hackberry Tertiary Project is to demonstrate the technical and economic feasibility of combining air injection with the Double Displacement Process for tertiary oil recovery. The Double Displacement Process is the gas displacement of a water invaded oil column for the purpose of recovering oil through gravity drainage. The novel aspect of this project is the use of air as the injection fluid. The target reservoir for the project is the Camerina C-1,2,3 sand located on the West Flank of West Hackberry Field in Cameron Parish, Louisiana. If successful, this project will demonstrate that the use of air injection in the Double Displacement Process can economically recover oil in reservoirs where tertiary oil recovery is presently uneconomic. The first quarter of 1996 was outstanding both in terms of volume of air injected and low cost operations. More air was injected during this quarter than in any preceding quarter. The compressors experienced much improved run time with minimal repairs. Low operating costs resulted from no repairs required for injection or production wells. A discussion of the following topics are contained herein: (1) performance summary for the injection and production wells, (2) air compressor operations, (3) updated bottom hole pressure data, (4) technology transfer activities and (5) plans for the upcoming quarter.

  12. 42 CFR 137.352 - What is contained in a construction project progress report?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES TRIBAL SELF-GOVERNANCE Construction Roles of Self-Governance Tribe in Establishing and Implementing Construction Project Agreements... 42 Public Health 1 2010-10-01 2010-10-01 false What is contained in a construction...

  13. Progress made towards enhancement of rheumatology education and practice in Zambia: review of an ILAR-supported project.

    PubMed

    Chipeta, James; Njobvu, Panganani; McGill, Paul E; Bucala, Richard

    2014-01-01

    The burden of non-communicable diseases such as musculoskeletal diseases in the developing world is often overshadowed by the more prevalent infectious diseases. Generally, there is gross underestimation of the burden of rheumatologic disease in the backdrop of scanty or indeed non-existent rheumatology services in these countries. Local studies conducted in the last two decades in Zambia have documented the increasing burden of rheumatologic conditions in the country. There are unfortunately negligible rheumatology services in the country both at tertiary or primary health-care facility levels. There is thus an urgent need to build capacity for these services so as to improve the care and management of rheumatic conditions. Here, we review progress made by an International League of Associations for Rheumatology (ILAR)-supported project that has run for the past 2 years (2012-2013) with the objective of enhancing paediatric and adult rheumatology education and practice so as to stimulate positive change in practice and related care services in Zambia. During this short time of the project, substantial progress has been made in the areas of paediatric and adult rheumatology services enhancement at the University Teaching Hospital, Lusaka: streamlining of referrals and follow-ups of rheumatology patients, laying foundations for short- and long-term medical education in rheumatology and raising public awareness of rheumatic diseases. The progress made by this grant underscores the suitability of the ILAR mission statement "think global, act local" demonstrating that even with minimum resources and networking, improvement of rheumatology care in developing countries is attainable.

  14. Physical view on migration modes

    PubMed Central

    Mierke, Claudia Tanja

    2015-01-01

    Cellular motility is essential for many processes such as embryonic development, wound healing processes, tissue assembly and regeneration, immune cell trafficing and diseases such as cancer. The migration efficiency and the migratory potential depend on the type of migration mode. The previously established migration modes such as epithelial (non-migratory) and mesenchymal (migratory) as well as amoeboid (squeezing motility) relay mainly on phenomenological criteria such as cell morphology and molecular biological criteria such as gene expression. However, the physical view on the migration modes is still not well understood. As the process of malignant cancer progression such as metastasis depends on the migration of single cancer cells and their migration mode, this review focuses on the different migration strategies and discusses which mechanical prerequisites are necessary to perform a special migration mode through a 3-dimensional microenvironment. In particular, this review discusses how cells can distinguish and finally switch between the migration modes and what impact do the physical properties of cells and their microenvironment have on the transition between the novel migration modes such as blebbing and protrusive motility. PMID:26192136

  15. Physical view on migration modes.

    PubMed

    Mierke, Claudia Tanja

    2015-01-01

    Cellular motility is essential for many processes such as embryonic development, wound healing processes, tissue assembly and regeneration, immune cell trafficing and diseases such as cancer. The migration efficiency and the migratory potential depend on the type of migration mode. The previously established migration modes such as epithelial (non-migratory) and mesenchymal (migratory) as well as amoeboid (squeezing motility) relay mainly on phenomenological criteria such as cell morphology and molecular biological criteria such as gene expression. However, the physical view on the migration modes is still not well understood. As the process of malignant cancer progression such as metastasis depends on the migration of single cancer cells and their migration mode, this review focuses on the different migration strategies and discusses which mechanical prerequisites are necessary to perform a special migration mode through a 3-dimensional microenvironment. In particular, this review discusses how cells can distinguish and finally switch between the migration modes and what impact do the physical properties of cells and their microenvironment have on the transition between the novel migration modes such as blebbing and protrusive motility.

  16. Kootenai River Fisheries Investigation : Stock Status of Burbot : Project Progress Report 2008 Annual Report.

    SciTech Connect

    Paragamian, Valughn L.; Laude Dorothy C.

    2008-12-26

    Objectives of this investigation were to (1) monitor the population status and recruitment of burbot Lota lota in the Kootenai River, Idaho and British Columbia, Canada during the winter of 2006-2007; (2) evaluate the selective withdrawal system in place at Libby Dam to maintain the river temperature near Bonners Ferry between 1-4 C (November-December) to improve burbot migration and spawning activity; and (3) determine if a hatching success of 10% of eyed burbot embryos could be achieved through extensive rearing and produce fingerlings averaging 9.8 cm in six months. Water temperature did not fall below the upper limit (4 C) until mid-January but was usually maintained between 1-4 C January through February and was acceptable. Snowpack was characterized by a 101% of normal January runoff forecast. Adult burbot were sampled with hoop nets and slat traps. Only three burbot were captured in hoop nets, all at Ambush Rock (rkm 244.5). No burbot were caught in either slat traps or juvenile sampling gear, indicating the population is nearly extirpated. Burbot catch per unit effort in hoop nets was 0.003 fish/net d. Extensive rearing was moved to a smaller private pond and will be reported in the 2008-2009 annual report.

  17. Compilation and analyses of emissions inventories for the NOAA atmospheric chemistry project. Progress report, August 1997

    SciTech Connect

    Benkovitz, C.M.

    1997-09-01

    Global inventories of anthropogenic emissions of oxides of nitrogen for circa 1985 and 1990 and non-methane volatile organic compounds (NMVOCs) for circa 1990 have been compiled by this project. Work on the inventories has been carried out under the umbrella of the Global Emissions Inventory Activity of the International Global Atmospheric Chemistry program. Global emissions of NOx for 1985 are estimated to be 21 Tg N/yr, with approximately 84% originating in the Northern Hemisphere. The global emissions for 1990 are 31 Tg N/yr for NOx and 173 Gg NMVOC/yr. Ongoing research activities for this project continue to address emissions of both NOx and NMVOCs. Future tasks include: evaluation of more detailed regional emissions estimates and update of the default 1990 inventories with the appropriate estimates; derivation of quantitative uncertainty estimates for the emission values; and development of emissions estimates for 1995.

  18. PROGRESS REPORT: COFIRING PROJECTS FOR WILLOW ISLAND AND ALBRIGHT GENERATING STATIONS

    SciTech Connect

    K. Payette; D. Tillman

    2001-07-01

    During the period April 1, 2001--June 30, 2001, Allegheny Energy Supply Co., LLC (Allegheny) accelerated construction of the Willow Island cofiring project, completed the installation of foundations for the fuel storage facility, the fuel receiving facility, and the processing building. Allegheny received all processing equipment to be installed at Willow Island. Allegheny completed the combustion modeling for the Willow Island project. During this time period construction of the Albright Generating Station cofiring facility was completed, with few items left for final action. The facility was dedicated at a ceremony on June 29. Initial testing of cofiring at the facility commenced. This report summarizes the activities associated with the Designer Opportunity Fuel program, and demonstrations at Willow Island and Albright Generating Stations. It details the construction activities at both sites along with the combustion modeling at the Willow Island site.

  19. A progress report on the Malaga Bend Experimental Salinity Alleviation Project, Eddy County, New Mexico

    USGS Publications Warehouse

    Cox, E.R.; Havens, J.S.

    1965-01-01

    At Malaga Bend on the Pecos River in Eddy County, New Mexico, a brine aquifer about 1950 feet below the stream channel has a pressure head about 10 feet above the river bed. This aquifer normally discharges about 430 tons of dissolved minerals daily into the river of which about 370 tons was sodium chloride. The Malaga Bend Experimental Salinity Alleviation Project, authorized by the U.S. Congress in 1958, Public Law 85-333,is an attempt to determine if the salinity content of the Pecos River below Malaga Bend can be decreased by reducing the inflow of saline water into the river at Malaga Bend by pumping from the brine aquifer. Construction for the project was supervised by the Bureau of Reclamation, and the collection of data and its interpretation were the responsibility cooperatively of the U. S. Geological Survey and the Pecos River Commission.

  20. The Agricultural Model Intercomparison and Improvement Project (AgMIP): Overview and Progress

    NASA Astrophysics Data System (ADS)

    Rosenzweig, C.; Hatfield, J.; Jones, J. W.; Ruane, A. C.

    2012-12-01

    The Agricultural Model Intercomparison and Improvement Project (AgMIP) is an international effort to assess the state of global agricultural modeling and to understand climate impacts on the agricultural sector. AgMIP connects the climate science, crop modeling, and agricultural economic modeling communities to generate probabilistic projections of current and future climate impacts. The goals of AgMIP are to improve substantially the characterization of risk of hunger and world food security due to climate change and to enhance adaptation capacity in both developing and developed countries. This presentation will describe the general approach of AgMIP and highlight its findings and activities. AgMIP crop model intercomparisons have been established for wheat (27 models participating), maize (25 models), and rice (15+ models), and are being established for sugarcane, soybean, sorghum/millet, and peanut. In coordination with these pilots, methodologies to utilize weather generators and downscaled climate simulations for agricultural applications are under development. An AgMIP global agricultural economics model intercomparison with participation of 11 international groups is ongoing, and a number of global biophysical models are currently being evaluated for future climate impacts on agricultural lands both as part of the Inter-Sectoral Impact Model Intercomparison Project (ISI-MIP) and for contribution to the IPCC Fifth Assessment Report (AR5). AgMIP is also organizing regional research efforts, and has already held workshops in South America, Sub-Saharan Africa, South Asia, Europe, and North America. Outcomes from these meetings have informed AgMIP activities, and 10 research teams from Sub-Saharan Africa and South Asia have been selected for project funding. Additional activities are planned for Australia and East Asia. As the AgMIP research community continues to work towards its goals, three key cross-cutting scientific challenges have emerged and are being

  1. Final Progress Report for Project Entitled: Quantum Dot Tracers for Use in Engineered Geothermal Systems

    SciTech Connect

    Rose, Peter; Bartl, Michael; Reimus, Paul; Williams, Mark; Mella, Mike

    2015-09-12

    The objective of this project was to develop and demonstrate a new class of tracers that offer great promise for use in characterizing fracture networks in EGS reservoirs. From laboratory synthesis and testing through numerical modeling and field demonstrations, we have demonstrated the amazing versatility and applicability of quantum dot tracers. This report summarizes the results of four years of research into the design, synthesis, and characterization of semiconductor nanocrystals (quantum dots) for use as geothermal tracers.

  2. Progress report on decommissioning activities at the Fernald Environmental Management Project (FEMP) site

    SciTech Connect

    1998-07-01

    The Fernald Environmental Management Project (FEMP), is located about 18 miles northwest of Cincinnati, Ohio. Between 1953 and 1989, the facility, then called the Feed Material Production Center or FMPC, produced uranium metal products used in the eventual production of weapons grade material for use by other US Department of Energy (DOE) sites. In 1989, FMPC`s production was suspended by the federal government in order to focus resources on environmental restoration versus defense production. In 1992, Fluor Daniel Fernald assumed responsibility for managing all cleanup activities at the FEMP under contract to the DOE. In 1990, as part of the remediation effort, the site was divided into five operable units based on physical proximity of contaminated areas, similar amounts of types of contamination, or the potential for a similar technology to be used in cleanup activities. This report continues the outline of the decontamination and decommissioning (D and D) activities at the FEMP site Operable Unit 3 (OU3) and provides an update on the status of the decommissioning activities. OU3, the Facilities Closure and Demolition Project, involves the remediation of more than 200 uranium processing facilities. The mission of the project is to remove nuclear materials stored in these buildings, then perform the clean out of the buildings and equipment, and decontaminate and dismantle the facilities.

  3. Colorado School of Mines low energy nuclear physics project. Final technical progress report

    SciTech Connect

    Cecil, F.E.

    1993-11-23

    This report summarizes the accomplishments of the project ``Studies of nuclear reactions at very low energies``. This project was undertaken in 1987 and completed in 1993. All but one of the major objectives of this study have been accomplished. Specifically the authors have completed their investigation of the (p,{gamma}) on light nuclei, a study of the Oppenheimer-Phillips effect, a measurements of the astrophysically interesting reaction D({alpha},{gamma}){sup 6}Li at low energies and an extension of the reaction D(d,{gamma}){sup 4}He to lower energies than previously observed. Preliminary investigation of te reaction {sup 7}Li({sup 3}He,p){sup 9}Be was begun and is continuing under a separate DOE grant. In addition to these tasks, they have completed some very interesting projects which were not included in the original proposal. These include a study of the (d,{gamma}) reactions on {sup 6}Li, {sup 7}Li and {sup 10}B and an investigation of the possibility of observing terrestrial antineutrinos from the beta decay chains of U and Th as a diagnostic of terrestrial heat flow.

  4. Progress on Fuel Receiving and Storage Decontamination Work at the West Valley Demonstration Project

    SciTech Connect

    Jablonski, J. F.; Al-Daouk, A. M.; Moore, H. R.

    2003-02-25

    The West Valley Demonstration Project (WVDP) removed the last of its spent nuclear fuel assemblies from an on-site storage pool last year and is now decontaminating its Fuel Receiving and Storage (FRS) Facility. The decontamination project will reduce the long-lived curie inventory, associated radiological hazards, and the operational costs associated with the maintenance of this facility. Workers at the WVDP conducted the first phase of the FRS decontamination project in late 2001 by removing 149 canisters that previously contained spent fuel assemblies from the pool. Removal of the canisters from the pool paved the way for nuclear divers to begin removing canister storage racks and other miscellaneous material from the FRS pool in February 2002. This was only the third time in the history of the WVDP that nuclear divers were used to perform underwater work. After decontaminating the pool, it will be drained slowly until all of the water is removed. The water will be processed through an ion exchanger to remove radioactive contaminants as it is being drained, and a fixative will be applied to the walls above the water surface to secure residual contamination.

  5. Geology, geochemistry, and geophysics of the Fry Canyon uranium/copper project site, southeastern Utah - Indications of contaminant migration

    USGS Publications Warehouse

    Otton, James K.; Zielinski, Robert A.; Horton, Robert J.

    2010-01-01

    The Fry Canyon uranium/copper project site in San Juan County, southeastern Utah, was affected by the historical (1957-68) processing of uranium and copper-uranium ores. Relict uranium tailings and related ponds, and a large copper heap-leach pile at the site represent point sources of uranium and copper to local soils, surface water, and groundwater. This study was designed to establish the nature, extent, and pathways of contaminant dispersion. The methods used in this study are applicable at other sites of uranium mining, milling, or processing. The uranium tailings and associated ponds sit on a bench that is as much as 4.25 meters above the level of the adjacent modern channel of Fry Creek. The copper heap leach pile sits on bedrock just south of this bench. Contaminated groundwater from the ponds and other nearby sites moves downvalley and enters the modern alluvium of adjacent Fry Creek, its surface water, and also a broader, deeper paleochannel that underlies the modern creek channel and adjacent benches and stream terraces. The northern extent of contaminated groundwater is uncertain from geochemical data beyond an area of monitoring wells about 300 meters north of the site. Contaminated surface water extends to the State highway bridge. Some uranium-contaminated groundwater may also enter underlying bedrock of the Permian Cedar Mesa Sandstone along fracture zones. Four dc-resistivity surveys perpendicular to the valley trend were run across the channel and its adjacent stream terraces north of the heap-leach pile and ponds. Two surveys were done in a small field of monitoring wells and two in areas untested by borings to the north of the well field. Bedrock intercepts, salt distribution, and lithologic information from the wells and surface observations in the well field aided interpretation of the geophysical profiles there and allowed interpretation of the two profiles not tested by wells. The geophysical data for the two profiles to the north of the

  6. Kootenai River Fisheries Investigations: Salmonid Studies Project Progress Report, 2007-2008 Annual Report.

    SciTech Connect

    Paragamian, Vaughn L.; Walters, Jody; Maiolie, Melo

    2009-04-09

    This research report addresses bull trout Salvelinus confluentus and Redband trout Oncorhynchus mykiss redd surveys, population monitoring, trout distribution, and abundance surveys in the Kootenai River drainage of Idaho. The bull trout is one of several sport fish native to the Kootenai River, Idaho that no longer supports a fishery. Because bull trout are listed under the Endangered Species Act, population data will be vital to monitoring status relative to recovery goals. Thirty-three bull trout redds were found in North and South Callahan creeks and Boulder Creek in 2007. This is a decrease from 2006 and 2005 and less than the high count in 2003. However, because redd numbers have only been monitored since 2002, the data series is too short to determine bull trout population trends based on redd counts. Redband trout still provide an important Kootenai River sport fishery, but densities are low, at least partly due to limited recruitment. The redband trout proportional stock density (PSD) in 2007 increased from 2006 for a second year after a two-year decline in 2004 and 2005. This may indicate increased recruitment to or survival in the 201-305 mm length group due to the minimum 406 mm (16 inches) length limit initiated in 2002. We conducted 13 redd surveys and counted 44 redband trout redds from May 7 to June 3, 2007 in a 3.8 km survey reach on Twentymile Creek. We surveyed streams in the Kootenai River valley to look for barriers to trout migration. Man-made barriers, for at least part of the year, were found on Caboose, Debt, Fisher, and Twenty Mile creeks. Removing these barriers would increase spawning and rearing habitat for trout and help to restore trout fisheries in the Kootenai River.

  7. The Walla Walla Basin Natural Production Monitoring and Evaluation Project : Progress Report, 1999-2002.

    SciTech Connect

    Contor, Craig R.; Sexton, Amy D.

    2003-06-02

    The Walla Walla Basin Natural Production Monitoring and Evaluation Project (WWNPME) was funded by Bonneville Power Administration (BPA) as directed by section 4(h) of the Pacific Northwest Electric Power Planning and Conservation Act of 1980 (P. L. 96-501). This project is in accordance with and pursuant to measures 4.2A, 4.3C.1, 7.1A.2, 7.1C.3, 7.1C.4 and 7.1D.2 of the Northwest Power Planning Council's (NPPC) Columbia River Basin Fish and Wildlife Program (NPPC 1994). Work was conducted by the Fisheries Program of the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) under the Walla Walla Basin Natural Production Monitoring and Evaluation Project (WWNPME). Chapter One provides an overview of the entire report and how the objectives of each statement of work from 1999, 2000, 2001, and 2002 contract years are organized and reported. Chapter One also provides background information relevant to the aquatic resources of the Walla Walla River Basin. Objectives are outlined below for the statements of work for the 1999, 2000, 2001 and 2002 contract years. The same objectives were sometimes given different numbers in different years. Because this document is a synthesis of four years of reporting, we gave objectives letter designations and listed the objective number associated with the statement of work for each year. Some objectives were in all four work statements, while other objectives were in only one or two work statements. Each objective is discussed in a chapter. The chapter that reports activities and findings of each objective are listed with the objective below. Because data is often interrelated, aspects of some findings may be reported or discussed in more than one chapter. Specifics related to tasks, approaches, methods, results and discussion are addressed in the individual chapters.

  8. General-purpose heat source project and space nuclear safety fuels program. Progress report, February 1980

    SciTech Connect

    Maraman, W.J.

    1980-05-01

    This formal monthly report covers the studies related to the use of /sup 238/PuO/sub 2/ in radioisotopic power systems carried out for the Advanced Nuclear Systems and Projects Division of the Los Alamos Scientific Laboratory. The two programs involved are: General-Purpose Heat Source Development and Space Nuclear Safety and Fuels. Most of the studies discussed here are of a continuing nature. Results and conclusions described may change as the work continues. Published reference to the results cited in this report should not be made without the explicit permission of the person in charge of the work.

  9. Progress of projection computed tomography by upgrading of the beamline 37XU of SPring-8

    SciTech Connect

    Terada, Yasuko Suzuki, Yoshio; Uesugi, Kentaro; Miura, Keiko

    2016-01-28

    Beamline 37XU at SPring-8 has been upgraded for nano-focusing applications. The length of the beamline has been extended to 80 m. By utilizing this length, the beamline has advantages for experiments such as X-ray focusing, X-ray microscopic imaging and X-ray computed tomography. Projection computed tomography measurements were carried out at experimental hutch 3 located 80 m from the light source. CT images of a microcapsule have been successfully obtained with a wide X-ray energy range.

  10. Progress in phases 2 and 3 of the Photovoltaic Manufacturing Technology Project (PVMaT)

    SciTech Connect

    Witt, C E; Mitchell, R L; Mooney, G D; Herwig, L O; Hasti, D; Sellers, R

    1993-10-01

    This first year of the process-specific activities of the Photo- voltaic Manufacturing Technology (PVMaT) project has been completed, and the first subcontracts for teamed efforts on R&D of a general nature have been awarded. A second solicitation for process-specific research and development (R&D) is in the evaluation stage for award of subcontracts. This paper describes the technical accomplishments of the first process-specific subcontracts (Phase 2A), the status of the teamed research (Phase 3A), and the status of the solicitation for the second process-specific solicitation (Phases 2B).

  11. [Tampa Electric Company IGCC project]. Final public design report; Technical progress report

    SciTech Connect

    1996-07-01

    This final Public Design Report (PDR) provides completed design information about Tampa Electric Company`s Polk Power Station Unit No. 1, which will demonstrate in a commercial 250 MW unit the operating parameters and benefits of the integration of oxygen-blown, entrained-flow coal gasification with advanced combined cycle technology. Pending development of technically and commercially viable sorbent for the Hot Gas Cleanup System, the HGCU also is demonstrated. The report is organized under the following sections: design basis description; plant descriptions; plant systems; project costs and schedule; heat and material balances; general arrangement drawings; equipment list; and miscellaneous drawings.

  12. Great Basin Paleoenvironmental Studies Project: Technical progress report, Second quarter (Year 2), September--December 1994

    SciTech Connect

    1994-12-31

    The paleobiotic and geomorphic records are being examined for the local and regional impact of past climates to assess Yucca Mountain`s suitability as a high-level nuclear waste repository. In particular these data are being used to provide estimates of the timing, duration and extremes of past periods of moister climate for use in hydrological models of local and regional recharge that are being formulated by USGS and other hydrologists for the Yucca Mountain area. The project includes botanical, faunal, and geomorphic components that will be integrated to accomplish this goal.

  13. DOE Waste Package Project. Quarterly progress report, October 1, 1993--December 31, 1993

    SciTech Connect

    Ladkany, S.G.

    1993-12-31

    The Waste Package Project research activities continued in all research areas. The areas include: Container structural and stress analysis; Nuclear fission criticality studies; Investigation of canister design concepts and corrosion studies; Heat transfer studies; Fluid flow in porous media and radionuclide transport in near field rock; Studies of stresses and stability of the rock formations resulting from the thermal loading of the fuel elements and the multi tunnel concept being analyzed; Characterization of a Faulted Rock Tunnel Model Using Photoelastic and Finite Element Studies; Experiment studies of the dynamic response of a flexible three-link robot using strain gages and Lagrange polynomials; and Robotic manipulation of the nuclear waste container.

  14. Retrieval process development and enhancements project Fiscal year 1995: Simulant development technology task progress report

    SciTech Connect

    Golcar, G.R.; Bontha, J.R.; Darab, J.G.

    1997-01-01

    The mission of the Retrieval Process Development and Enhancements (RPD&E) project is to develop an understanding of retrieval processes, including emerging and existing technologies, gather data on these technologies, and relate the data to specific tank problems such that end-users have the requisite technical bases to make retrieval and closure decisions. The development of waste simulants is an integral part of this effort. The work of the RPD&E simulant-development task is described in this document. The key FY95 accomplishments of the RPD&E simulant-development task are summarized below.

  15. Magnetic Earth Ionosphere Resonant Frequencies (MEIRF) project. Semiannual progress report, September 1992-March 1993

    SciTech Connect

    Spaniol, C.

    1993-06-01

    The West Virginia State College Community College Division NASA Magnetic Earth Ionosphere Resonant Frequencies (MEIRF) study is described. During this contract period, the two most significant and professionally rewarding events were the presentation of the research activity at the Sir Isaac Newton Conference in St. Petersburg, Russia, and the second Day of Discovery Conference, focusing on economic recovery in West Virginia. An active antenna concept utilizing a signal feedback principle similar to regenerative receivers used in early radio was studied. The device has potential for ELF research and other commercial applications for improved signal reception. Finally, work continues to progress on the development of a prototype monitoring station. Signal monitoring, data display, and data storage are major areas of activity. In addition, the authors plan to continue their dissemination of research activity through presentations at seminars and other universities.

  16. Chernobyl Studies Project: Working group 7.0, Environmental transport and health effects. Progress report, March--September 1994

    SciTech Connect

    Anspaugh, L.R.; Hendrickson, S.M.

    1994-12-01

    In April 1988, the US and the former-USSR signed a Memorandum of Cooperation (MOC) for Civilian Nuclear Reactor Safety; this MOC was a direct result of the accident at the Chernobyl Nuclear Power Plant Unit 4 and the following efforts by the two countries to implement a joint program to improve the safety of nuclear power plants and to understand the implications of environmental releases. A Joint Coordinating Committee for Civilian Nuclear Reactor Safety (JCCCNRS) was formed to implement the MOC. The JCCCNRS established many working groups; most of these were the responsibility of the Nuclear Regulatory Commission, as far as the US participation was concerned. The lone exception was Working Group 7 on Environmental Transport and Health Effects, for which the US participation was the responsibility of the US Department of Energy (DOE). The purpose of Working Group 7 was succintly stated to be, ``To develop jointly methods to project rapidly the health effects of any future nuclear reactor accident.`` To implement the work DOE then formed two subworking groups: 7.1 to address Environmental Transport and 7.2 to address Health Effects. Thus, the DOE-funded Chernobyl Studies Project began. The majority of the initial tasks for this project are completed or near completion. The focus is now turned to the issue of health effects from the Chernobyl accident. Currently, we are involved in and making progress on the case-control and co-hort studies of thyroid diseases among Belarussian children. Dosimetric aspects are a fundamental part of these studies. We are currently working to implement similar studies in Ukraine. A major part of the effort of these projects is supporting these studies, both by providing methods and applications of dose reconstruction and by providing support and equipment for the medical teams.

  17. History and progress of the North American Soil Geochemical Landscapes Project, 2001-2010

    USGS Publications Warehouse

    Smith, David B.; Cannon, William F.; Woodruff, Laurel G.; Rivera, Francisco Moreira; Rencz, Andrew N.; Garrett, Robert G.

    2012-01-01

    In 2007, the U.S. Geological Survey, the Geological Survey of Canada, and the Mexican Geological Survey initiated a low-density (1 site per 1600 km2, 13323 sites) geochemical and mineralogical survey of North American soils (North American Soil Geochemical Landscapes Project). Sampling and analytical protocols were developed at a series of workshops in 20032004 and pilot studies were conducted from 20042007. The ideal sampling protocol at each site includes a sample from 05 cm depth, a composite of the soil A horizon, and a sample from the soil C horizon. The 3, HClO4, and HF. Separate methods are used for As, Hg, Se, and total C on this same size fraction. The major mineralogical components are determined by a quantitative X-ray diffraction method. Sampling in the conterminous U.S. was completed in 2010 (c. 4800 sites) with chemical and mineralogical analysis currently underway. In Mexico, approximately 66% of the sampling (871 sites) had been done by the end of 2010 with completion expected in 2012. After completing sampling in the Maritime provinces and portions of other provinces (472 sites, 7.6% of the total), Canada withdrew from the project in 2010. Preliminary results for a swath from the central U.S. to Florida clearly show the effects of soil parent material and climate on the chemical and mineralogical composition of soils. A sample archive will be established and made available for future investigations.

  18. Mexico City air quality: Progress of an international collaborative project to define air quality management options

    SciTech Connect

    Streit, G.E.

    1992-01-01

    Mexico City, faces a severe air pollution problem due to a combination of circumstances. The city is in a high mountain basin at a subtropical latitude. The basin setting inhibits dispersion of pollution and contributes to frequent wintertime thermal inversions which further trap pollutants near the surface. The elevation and latitude combine to provide plentiful sunshine which, in comparison to more northern latitudes, is enhanced in the UV radiation which drives atmospheric photochemistry to produce secondary pollutants such as ozone. The Area Metropolitana de la Ciudad de Mexico AMCW is defined to include the 16 delegations of the Federal District (D.F.) and 17 highly urbanized municipalities in the State of Mexico which border the D.F. The 1990 census (XI Censo General de Poblacion y Vivienda de 1990) records that slightly over 15 million people live in the AMCM. There are numerous other nearby communities which are in the airshed region of Mexico City, but which are not included in the definition and population of the AMCM. The Mexico City Air Quality Research Initiative is one project that is examining the complex relationship between air pollution, economic growth, societal values, and air quality management policies. The project utilizes a systems approach including computer modeling, comprehensive measurement studies of Mexico City's air pollutants, environmental chemical reaction studies and socioeconomic analysis. Los Alamos National Laboratory (USA) and the Mexican Petroleum Institute are the designated lead institutions.

  19. Mexico City air quality: Progress of an international collaborative project to define air quality management options

    SciTech Connect

    Streit, G.E.

    1992-10-01

    Mexico City, faces a severe air pollution problem due to a combination of circumstances. The city is in a high mountain basin at a subtropical latitude. The basin setting inhibits dispersion of pollution and contributes to frequent wintertime thermal inversions which further trap pollutants near the surface. The elevation and latitude combine to provide plentiful sunshine which, in comparison to more northern latitudes, is enhanced in the UV radiation which drives atmospheric photochemistry to produce secondary pollutants such as ozone. The Area Metropolitana de la Ciudad de Mexico AMCW is defined to include the 16 delegations of the Federal District (D.F.) and 17 highly urbanized municipalities in the State of Mexico which border the D.F. The 1990 census (XI Censo General de Poblacion y Vivienda de 1990) records that slightly over 15 million people live in the AMCM. There are numerous other nearby communities which are in the airshed region of Mexico City, but which are not included in the definition and population of the AMCM. The Mexico City Air Quality Research Initiative is one project that is examining the complex relationship between air pollution, economic growth, societal values, and air quality management policies. The project utilizes a systems approach including computer modeling, comprehensive measurement studies of Mexico City`s air pollutants, environmental chemical reaction studies and socioeconomic analysis. Los Alamos National Laboratory (USA) and the Mexican Petroleum Institute are the designated lead institutions.

  20. Standard terminology for phenotypic variations: the elements of morphology project, its current progress, and future directions.

    PubMed

    Carey, John C; Allanson, Judith E; Hennekam, Raoul C M; Biesecker, Leslie G

    2012-05-01

    In 2005, the authors of this article formed an international working group to develop standardized definitions and terms to describe the physical variations used in human phenotypic analyses. This project, which came to be known as the Elements of Morphology, resulted in six articles proposing consensus definitions for almost 400 phenotypic variations of the head and face; periorbital region; ear, nose, and philtrum; mouth and lips; and hands and feet. Every variation was accompanied by a representative figure depicting the feature. The articles were published in the January 2009 issue of the American Journal of Medical Genetics Part A and are available for free access on both the Journal's Web page and a National Institutes of Health-based site. The publication of the Elements' definitions has spawned an ongoing dialogue about the proposed terms to describe the phenotype. The working group considered the six articles as only the first step in the process, and four more articles on proposed terminology for the trunk, genital region, skin, and remainder of the limb terms are in preparation. The secondary outcome of the Elements project is the provision of a working methodology for the establishment of standardized terminology and definitions for phenotype analysis in general.

  1. Progress Report on the GROWTH (GNSS Reflectometry for Ocean Waves, Tides, and Height) Research Project

    NASA Astrophysics Data System (ADS)

    Ichikawa, Kaoru; Akiyama, Hiroaki; Ebinuma, Takuji; Isoguchi, Osamu; Kimura, Noriaki; Kitazawa, Yukihito; Konda, Masanori; Kouguchi, Nobuyuki; Tamura, Hitoshi; Tomita, Hiroyuki; Yoshikawa, Yutaka; Waseda, Takuji

    2016-04-01

    There has been considerable interest in GNSS Reflectometry (GNSS-R) as a new remote-sensing method. We have started a research program for GNSS-R applications on oceanographic observations under the contract with MEXT (Ministry of Education Culture, Sports, Science and Technology, JAPAN) and launched a Japanese research consortium, GROWTH. It is aiming to evaluate the capabilities of GNSS-R observations for oceanographic phenomena with different time scales, such as ocean waves (1/10 to tens of seconds), tides (one or half days), and sea surface dynamic height (a few days to years). In situ observations of ocean wave spectrum, wind speed vertical profile, and sea surface height will be quantitatively compared with equivalent estimates from simultaneous GNSS-R measurements. The GROWTH project will utilize different types of observation platforms; marine observation towers (about 20 m height), multi-copters (about 100 to 200 m height), and much higher-altitude CYGNSS data. Cross-platform data, together with in situ oceanographic observations, will be compared after adequate temporal averaging that accounts differences of the footprint sizes and temporal and spatial scales of oceanographic phenomena. This paper will provide overview of the GROWTH project, preliminary test results obtained by the multi-sensor platform at observation towers, and preparation status of a ground station that will be supplied to receive CYGNSS data at Japan.

  2. UP2 400 High Activity Oxide Legacy Waste Retrieval Project Scope and Progress-13048

    SciTech Connect

    Chabeuf, Jean-Michel; Varet, Thierry

    2013-07-01

    The High Activity Oxide facility (HAO) reprocessed sheared and dissolved 4500 metric tons of light water reactor fuel the fuel of the emerging light water reactor spent fuel between 1976 and 1998. Over the period, approximately 2200 tons of process waste, composed primarily of sheared hulls, was produced and stored in a vast silo in the first place, and in canisters stored in pools in subsequent years. Upon shutdown of the facility, AREVA D and D Division in La Hague launched a thorough investigation and characterization of the silos and pools content, which then served as input data for the definition of a legacy waste retrieval and reconditioning program. Basic design was conducted between 2005 and 2007, and was followed by an optimization phase which lead to the definition of a final scenario and budget, 12% under the initial estimates. The scenario planned for the construction of a retrieval and reconditioning cell to be built on top of the storage silo. The retrieved waste would then be rinsed and sorted, so that hulls could subsequently be sent to La Hague high activity compacting facility, while resins and sludge would be cemented within the retrieval cell. Detailed design was conducted successfully from 2008 until 2011, while a thorough research and development program was conducted in order to qualify each stage of the retrieval and reconditioning process, and assist in the elaboration of the final waste package specification. This R and D program was defined and conducted as a response and mitigation of the major project risks identified during the basic design process. Procurement and site preparatory works were then launched in 2011. By the end of 2012, R and D is nearly completed, the retrieval and reconditioning process have been secured, the final waste package specification is being completed, the first equipment for the retrieval cell is being delivered on site, while preparation works are allowing to free up space above and around the silo, to

  3. The Point-Focusing Thermal and Electric Applications Project - A progress report. [small solar power systems applications

    NASA Technical Reports Server (NTRS)

    Marriott, A. T.

    1979-01-01

    The paper discusses the Point-Focusing Thermal and Electric Applications Project which encompasses three primary activities: (1) applications analysis and development, in which potential markets for small power systems (less than 10 MWe) are identified and characterized in order to provide requirements for design and information for activities relating to market development; (2) systems engineering and development, for analyses that will define the most appropriate small power system designs based on specific user requirements; and (3) experiment implementation and test, which deals with the design and placement of engineering experiments in various applications environments in order to test the readiness of the selected technology in an operational setting. Progress to date and/or key results are discussed throughout the text.

  4. Trade and migration: the case of NAFTA.

    PubMed

    Martin, P L

    1993-01-01

    "This article provides background information on NAFTA [the North American Free Trade Agreement], reviews data on its economic effects, and summarizes studies and projections of NAFTA's likely effects on Mexico-to-U.S. migration. Migration factors (demand-pull, supply-push, and networks) are examined to determine whether NAFTA's effect on economic development particularly in the border areas will accelerate or retard migration. The conclusion is that NAFTA is likely to produce a temporary migration hump, slightly raising already high migration levels in the 1990s, but reducing the volume of Mexico-to-U.S. migration that would otherwise occur over subsequent decades."

  5. Captive Rearing Program for Salmon River Chinook Salmon : Project Progress Report, 2001 Annual Report.

    SciTech Connect

    Venditti, David A.

    2003-10-01

    distributed themselves throughout the study section and displayed a progression of habitat associations and behavior consistent with progressing maturation and the onset of spawning. Five of the 18 redds spawned by captive-reared parents were hydraulically sampled to assess survival to the eyed stage of development. Eyed-eggs were collected from four of these, and survival to this stage ranged from 0%-89%. Expanding these results to the remaining redds produced an estimate of 15,000 eyed-eggs being produced by captive-reared fish.

  6. Captive Rearing Program for Salmon River Chinook Salmon, 2000 Project Progress Report.

    SciTech Connect

    Venditti, David A.

    2002-04-01

    During 2000, the Idaho Department of Fish and Game (IDFG) continued to develop techniques to rear chinook salmon Oncorhynchus tshawytscha to sexual maturity in captivity and to monitor their reproductive performance under natural conditions. Eyed-eggs were collected to establish captive cohorts from three study streams and included 503 eyed-eggs from East Fork Salmon River (EFSR), 250 from the Yankee Fork Salmon River, and 304 from the West Fork Yankee Fork Salmon River (WFYF). After collection, the eyed-eggs were immediately transferred to the Eagle Fish Hatchery, where they were incubated and reared by family group. Juveniles collected the previous summer were PIT and elastomer tagged and vaccinated against vibrio Vibrio spp. and bacterial kidney disease before the majority (approximately 75%) were transferred to the National Marine Fisheries Service, Manchester Marine Experimental Station for saltwater rearing through sexual maturity. Smolt transfers included 158 individuals from the Lemhi River (LEM), 193 from the WFYF, and 372 from the EFSR. Maturing fish transfers from the Manchester facility to the Eagle Fish Hatchery included 77 individuals from the LEM, 45 from the WFYF, and 11 from the EFSR. Two mature females from the WFYF were spawned in captivity with four males in 2000. Only one of the females produced viable eggs (N = 1,266), which were placed in in-stream incubators by personnel from the Shoshone-Bannock Tribe. Mature adults (N = 70) from the Lemhi River were released into Big Springs Creek to evaluate their reproductive performance. After release, fish distributed themselves throughout the study section and displayed a progression of habitat associations and behavior consistent with progressing maturation and the onset of spawning. Fifteen of the 17 suspected redds spawned by captive-reared parents in Big Springs Creek were hydraulically sampled to assess survival to the eyed stage of development. Eyed-eggs were collected from 13 of these, and

  7. Coal-fired MHD combustor development project: Phase IIIB. First quarterly technical progress report, 13 January-30 April 1982

    SciTech Connect

    1982-05-20

    The first quarterly technical progress report of the Coal-Fired MHD Combustor Development Project (Phase IIIB) presents the accomplishments during the period 13 January to 30 April, 1982. The scope of work covered by this quarterly report relates to those tasks associated with preparing the TRW 20 MW/sub t/ MHD coal combustor for delivery to AERL for integrated power tests and the work associated with the preliminary design of a 50 MW/sub t/ coal-fired combustor. Progress during this reporting period is described. All new 20 MW/sub t/ hardware was designed and fabricated. Interface coordination meetings were conducted with AERL and DOE. Interface control drawings were completed and a 20 MW/sub t/ coal combustion User's manual was delivered to AERL. The User's manual contained a shipping plan, a crew training plan, an assembly manual, interface documentation and recommended operating procedures. Facility/combustor set-up was completed and the pre-delivery 20 MW/sub t/ coal combustor qualification test series was completed. The 50 MW/sub t/ coal-fired MHD combustor preliminary designs were finalized and the DOE preliminary design review (PDR) was successfully completed.

  8. Prediction of radiographic progression in synovitis-positive joints on maximum intensity projection of magnetic resonance imaging in rheumatoid arthritis.

    PubMed

    Akai, Takanori; Taniguchi, Daigo; Oda, Ryo; Asada, Maki; Toyama, Shogo; Tokunaga, Daisaku; Seno, Takahiro; Kawahito, Yutaka; Fujii, Yosuke; Ito, Hirotoshi; Fujiwara, Hiroyoshi; Kubo, Toshikazu

    2016-04-01

    Contrast-enhanced magnetic resonance imaging with maximum intensity projection (MRI-MIP) is an easy, useful imaging method to evaluate synovitis in rheumatoid hands. However, the prognosis of synovitis-positive joints on MRI-MIP has not been clarified. The aim of this study was to evaluate the relationship between synovitis visualized by MRI-MIP and joint destruction on X-rays in rheumatoid hands. The wrists, metacarpophalangeal (MP) joints, and proximal interphalangeal (PIP) joints of both hands (500 joints in total) were evaluated in 25 rheumatoid arthritis (RA) patients. Synovitis was scored from grade 0 to 2 on the MRI-MIP images. The Sharp/van der Heijde score and Larsen grade were used for radiographic evaluation. The relationships between the MIP score and the progression of radiographic scores and between the MIP score and bone marrow edema on MRI were analyzed using the trend test. As the MIP score increased, the Sharp/van der Heijde score and Larsen grade progressed severely. The rate of bone marrow edema-positive joints also increased with higher MIP scores. MRI-MIP imaging of RA hands is a clinically useful method that allows semi-quantitative evaluation of synovitis with ease and can be used to predict joint destruction.

  9. Great Basin paleoenvironmental studies project; Third quarterly technical progress report, December 1993--February 1994

    SciTech Connect

    1994-04-01

    Examination of the paleolithic and geomorphic records to determine the local and regional impact of past climates will advance assessment of Yucca Mountain`s suitability as a high-level nuclear waste repository. The project includes the integration of botanical, faunal, and geomorphic components to accomplish this goal. Paleobotanical studies will reconstruct the response of vegetation to climate change at the community and the organismal levels by integrating data obtained from nearly continuous sediment records of pollen, plant macrofossils, and stable isotopes from fossil woodrat middens. The goal of the paleofaunas study is to construct a history of Great Basin vertebrates, particularly mammals, that will provide empirical evidence of past environmental and climatic conditions within the Great Basin as it is recorded by the animals. Taxonomic composition of archaeological and paleontological faunas from various areas within the Great Basin and morphological change within individual mammalian taxa at specific localities are being investigated to monitor faunal response to changing environmental conditions. The objective of the geomorphology component of the paleoenvironmental program is to document the responses of surficial processes and landforms to the climatic changes documented by studies of packrat middens, pollen, and faunal distributions. The project will focus on: (1) stratigraphic relationships between lake deposits and aeolian or fluvial sediments and landforms; (2) cut and fill sequences in floodplain and river-channel deposits; (3) identification of periods of dune mobility and stability; (4) documentation of episodes of alluvial fan and terrace development and erosion; and (5) correlation of (3) and (4) to climatically driven lake-level fluctuation as revealed by shoreline features such as strandlines and beach ridges. Accomplishments for this period are presented for these studies.

  10. TIDD PFBC Demonstration Project. First quarterly technical progress report, CY 1993

    SciTech Connect

    Not Available

    1993-04-01

    This is the 24th Technical Progress Report submitted in connection with the cooperative agreement between the DOE and the Ohio Power Company for the Tidd Pressurized Fluidized Bed Combustion (PFBC) Demonstration Plant. This report covers the period from January 1, 1993 to March 31, 1993. The following activities are reported: The unit was operated for a total of 331 hours (including gas turbine air prewarming). There were three gas turbine starts, five bed preheater starts, and two operating periods with coal fire. The peak gross output of 61 MWH was achieved for the period of 2200 to 2300 hours on January 20, 1993. The longest coal fire was 273 hours beginning at 0605 hours on January 20, 1993; total gross generation was 13,453 MWH, and coal consumption was 6,481 tons; The sorbent fines injection system was installed and is ready for use; A totally new secondary ash removal system was designed; New sparge ducts are being fabricated to replace the existing ducts; The plant was found to be in compliance with applicable Ohio regulation after an EPA inspection; and The unit has been out of service since early February due to the failure of the gas turbine. Replacement parts are being fabricated

  11. Tidd PFBC Demonstration Project fourth quarterly technical progress report, CY 1992

    SciTech Connect

    Not Available

    1993-01-01

    This is the 23rd technical progress report submitted to the Department of Energy in connection with the cooperative agreement between the DOE and the Ohio Power Company for the Tidd PFBC Demonstration Plant. This report covers the period from October 1, 1992 to December 31, 1992. Major activities during this period involve: (1) The unit was operated for a total of 714 hours (including gas turbine air prewarming). There were seven gas turbine starts, seven bed preheater starts, and seven operating periods with coal fire. The peak gross output of 64 MWH was achieved for the period of 1000 to 1100 hours on November 23, 1992. The longest coal fire was 285 hours beginning at 1211 hours on November 25, 1992. (2) Total gross generation was 24,643, and coal consumption was 11,900 tons. (3) The hot gas clean up system was commissioned. (4) Active end fluidization system to address sparge duct cracking and deformation problem was jointly initiated by ABB carbon, B&W and AEPSC. (5) All testing continued using Plum Run dolomite. This approach was taken as a conservative means to avoid sintering and unit trips which were encountered during the previous two start-ups in September using limestone and (6) monitoring of solid, liquid and gaseous waste streams, as detailed in the operations phase monitoring requirements in the EMP, were performed.

  12. Tidd PFBC Demonstration Project fourth quarterly technical progress report, CY 1992

    SciTech Connect

    Not Available

    1993-01-01

    This is the 23rd technical progress report submitted to the Department of Energy in connection with the cooperative agreement between the DOE and the Ohio Power Company for the Tidd PFBC Demonstration Plant. This report covers the period from October 1, 1992 to December 31, 1992. Major activities during this period involve: (1) The unit was operated for a total of 714 hours (including gas turbine air prewarming). There were seven gas turbine starts, seven bed preheater starts, and seven operating periods with coal fire. The peak gross output of 64 MWH was achieved for the period of 1000 to 1100 hours on November 23, 1992. The longest coal fire was 285 hours beginning at 1211 hours on November 25, 1992. (2) Total gross generation was 24,643, and coal consumption was 11,900 tons. (3) The hot gas clean up system was commissioned. (4) Active end fluidization system to address sparge duct cracking and deformation problem was jointly initiated by ABB carbon, B W and AEPSC. (5) All testing continued using Plum Run dolomite. This approach was taken as a conservative means to avoid sintering and unit trips which were encountered during the previous two start-ups in September using limestone and (6) monitoring of solid, liquid and gaseous waste streams, as detailed in the operations phase monitoring requirements in the EMP, were performed.

  13. TIDD PFBC Demonstration Project: Third quarterly technical progress report 1992, CY 1992

    SciTech Connect

    Not Available

    1992-10-01

    This is the 22nd Technical Progress Report submitted to the Department of Energy in connection with the Cooperative Agreement between the DOE and the Ohio Power Company for the Tidd PFBC Demonstration Plant. This report covers the period from July 1, 1992 to September 30, 1992. The unit was operated for a total of 903 hours (including gas turbine air prewarming). There were 9 gas turbine starts, 11 preheating starts, and 8 operating periods with coal fire. The peak gross output of 59 MWH was achieved for the period of 1600 to 1700 hours on September 23, 1992. The longest coal fire was 422 hourb beginning at 1349 hours on August 9, 1992. Total gross generation was 32,418 MWH, and coal consumption was 15,846 tons. Testing was completed on the gas turbine blade resonance frequency problem. The report showed that a resonant frequency problem existing at high LPT speeds and at a mostly closed guide vane position. An operating curve was developed by ABBC to avoid the points of blade resonance. Monitoring of solid, liquid and gaseous waste streams, as detailed in the operations phase monitoring requirements in the EMP, were performed throughout the quarter.

  14. Progress of the Keda Torus eXperiment Project in China: design and mission

    NASA Astrophysics Data System (ADS)

    Liu, Wandong; Mao, Wenzhe; Li, Hong; Xie, Jinlin; Lan, Tao; Liu, Ahdi; Wan, Shude; Wang, Hai; Zheng, Jian; Wen, Xiaohui; Zhou, Haiyang; You, Wei; Li, Chenguang; Bai, Wei; Tu, Cui; Tan, Mingsheng; Luo, Bing; Fu, Chenshuo; Huang, Fangcheng; Xiao, Bingjia; Luo, Zhengping; Shen, Biao; Fu, Peng; Yang, Lei; Song, Yuntao; Yang, Qingxi; Zheng, Jinxing; Xu, Hao; Zhang, Ping; Xiao, Chijin; Ding, Weixing

    2014-09-01

    The Keda Torus eXperiment (KTX) is a medium-sized reversed field pinch (RFP) device under construction at the University of Science and Technology of China. The KTX has a major radius of 1.4 m and a minor radius of 0.4 m with an Ohmic discharge current up to 1 MA. The expected electron density and temperature are, respectively, 2 × 1019 m-3 and 800 eV. A combination of a stainless steel vacuum chamber and a thin copper shell (with a penetration time of 20 ms) surrounding the plasma provides an opportunity for studying resistive wall mode instabilities. The unique double-C design of the KTX vacuum vessel allows access to the interior of the KTX for easy first-wall modifications and investigations of power and particle handling, a largely unexplored territory in RFP research leading to demonstration of the fusion potential of the RFP concept. An active feedback mode control system is designed and will be implemented in the second phase of the KTX program. The recent progress of this program will be presented, including the design of the vacuum vessel, magnet systems and power supplies.

  15. Geothermal direct-heat utilization assistance. Federal Assistance Program quarterly project progress report, April 1--June 30, 1998

    SciTech Connect

    1998-07-01

    This report summarizes geothermal technical assistance, R and D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the third quarter of FY98 (April--June, 1998). It describes 231 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with included requests for general information including material for high school and university students, and material on geothermal heat pumps, resource and well data, spacing heating and cooling, greenhouses, aquaculture, equipment, district heating, resorts and spas, industrial applications, snow melting and electric power. Research activities include work on model construction specifications for line shaft submersible pumps and plate heat exchangers, and a comprehensive aquaculture developers package. A brochure on Geothermal Energy in Klamath County was developed for state and local tourism use. Outreach activities include the publication of the Quarterly Bulletin (Vol. 19, No. 2) with articles on research at the Geo-Heat Center, sustainability of geothermal resources, injection well drilling in Boise, ID and a greenhouse project in the Azores. Other outreach activities include dissemination of information mainly through mailings of publications, tours of local geothermal uses, geothermal library acquisitions and use, participation in workshops, short courses and technical meetings by the staff, and progress monitor reports on geothermal activities.

  16. COMPILATION AND ANALYSES OF EMISSIONS INVENTORIES FOR THE NOAA ATMOSPHERIC CHEMISTRY PROJECT. PROGRESS REPORT, AUGUST 1997.

    SciTech Connect

    BENKOVITZ,C.M.

    1997-09-01

    Global inventories of anthropogenic emissions of oxides of nitrogen (NO{sub x}) for circa 1985 and 1990 and Non-Methane Volatile Organic Compounds (NMVOCs) for circa 1990 have been compiled by this project. Work on the inventories has been carried out under the umbrella of the Global Emissions Inventory Activity (GEIA) of the International Global Atmospheric Chemistry (IGAC) Program. The 1985 NO{sub x} inventory was compiled using default data sets of global emissions that were refined via the use of more detailed regional data sets; this inventory is being distributed to the scientific community at large as the GEIA Version 1A inventory. Global emissions of NO{sub x} for 1985 are estimated to be 21 Tg N y{sup -1}, with approximately 84% originating in the Northern Hemisphere. The 1990 inventories of NO{sub x} and NMVOCs were compiled using unified methodologies and data sets in collaboration with the Netherlands National Institute of Public Health and Environmental Protection (Rijksinstituut Voor Volksgezondheid en Milieuhygiene, RIVM) and the Division of Technology for Society of the Netherlands Organization for Applied Scientific Research, (IMW-TNO); these emissions will be used as the default estimates to be updated with more accurate regional data. The NMVOC inventory was gridded and speciated into 23 chemical categories. The resulting global emissions for 1990 are 31 Tg N yr{sup -1} for NO{sub x} and 173 Gg NMVOC yr{sup -1}. Emissions of NO{sub x} are highest in the populated and industrialized areas of eastern North America and across Europe, and in biomass burning areas of South America, Africa, and Asia. Emissions of NMVOCs are highest in biomass burning areas of South America, Africa, and Asia. The 1990 NO{sub x} emissions were gridded to 1{sup o} resolution using surrogate data, and were given seasonal, two-vertical-level resolution and speciated into NO and NO{sub 2} based on proportions derived from the 1985 GEIA Version 1B inventory. Global NMVOC

  17. REDUCING UNCERTAINTIES IN MODEL PREDICTIONS VIA HISTORY MATCHING OF CO2 MIGRATION AND REACTIVE TRANSPORT MODELING OF CO2 FATE AT THE SLEIPNER PROJECT

    SciTech Connect

    Zhu, Chen

    2015-03-31

    An important question for the Carbon Capture, Storage, and Utility program is “can we adequately predict the CO2 plume migration?” For tracking CO2 plume development, the Sleipner project in the Norwegian North Sea provides more time-lapse seismic monitoring data than any other sites, but significant uncertainties still exist for some of the reservoir parameters. In Part I, we assessed model uncertainties by applying two multi-phase compositional simulators to the Sleipner Benchmark model for the uppermost layer (Layer 9) of the Utsira Sand and calibrated our model against the time-lapsed seismic monitoring data for the site from 1999 to 2010. Approximate match with the observed plume was achieved by introducing lateral permeability anisotropy, adding CH4 into the CO2 stream, and adjusting the reservoir temperatures. Model-predicted gas saturation, CO2 accumulation thickness, and CO2 solubility in brine—none were used as calibration metrics—were all comparable with the interpretations of the seismic data in the literature. In Part II & III, we evaluated the uncertainties of predicted long-term CO2 fate up to 10,000 years, due to uncertain reaction kinetics. Under four scenarios of the kinetic rate laws, the temporal and spatial evolution of CO2 partitioning into the four trapping mechanisms (hydrodynamic/structural, solubility, residual/capillary, and mineral) was simulated with ToughReact, taking into account the CO2-brine-rock reactions and the multi-phase reactive flow and mass transport. Modeling results show that different rate laws for mineral dissolution and precipitation reactions resulted in different predicted amounts of trapped CO2 by carbonate minerals, with scenarios of the conventional linear rate law for feldspar dissolution having twice as much mineral trapping (21% of the injected CO2) as scenarios with a Burch-type or Alekseyev et al.–type rate law for feldspar dissolution (11%). So far, most reactive transport modeling (RTM) studies for

  18. MHD Integrated Topping Cycle Project. Thirteenth quarterly technical progress report, August 1, 1990--October 31, 1990

    SciTech Connect

    Not Available

    1992-01-01

    The overall objective of the project is to design and construct prototypical hardware for an integrated MHD topping cycle, and conduct long duration proof-of-concept tests of integrated system at the US DOE Component Development and Integration Facility in Butte, Montana. The results of the long duration tests will augment the existing engineering design data base on MHD power train reliability, availability, maintainability, and performance, and will serve as a basis for scaling up the topping cycle design to the next level of development, an early commercial scale power plant retrofit. The components of the MHD power train to be designed, fabricated, and tested include: A slagging coal combustor with a rated capacity of 50 MW thermal input, capable of operation with an Eastern (Illinois {number_sign}6) or Western (Montana Rosebud) coal, a segmented supersonic nozzle, a supersonic MHD channel capable of generating at least 1.5 MW of electrical power, a segmented supersonic diffuser section to interface the channel with existing facility quench and exhaust systems, a complete set of current control circuits for local diagonal current control along the channel, and a set of current consolidation circuits to interface the channel with the existing facility inverter.

  19. REBL: design progress toward 16 nm half-pitch maskless projection electron beam lithography

    NASA Astrophysics Data System (ADS)

    McCord, Mark A.; Petric, Paul; Ummethala, Upendra; Carroll, Allen; Kojima, Shinichi; Grella, Luca; Shriyan, Sameet; Rettner, Charles T.; Bevis, Chris F.

    2012-03-01

    REBL (Reflective Electron Beam Lithography) is a novel concept for high speed maskless projection electron beam lithography. Originally targeting 45 nm HP (half pitch) under a DARPA funded contract, we are now working on optimizing the optics and architecture for the commercial silicon integrated circuit fabrication market at the equivalent of 16 nm HP. The shift to smaller features requires innovation in most major subsystems of the tool, including optics, stage, and metrology. We also require better simulation and understanding of the exposure process. In order to meet blur requirements for 16 nm lithography, we are both shrinking the pixel size and reducing the beam current. Throughput will be maintained by increasing the number of columns as well as other design optimizations. In consequence, the maximum stage speed required to meet wafer throughput targets at 16 nm will be much less than originally planned for at 45 nm. As a result, we are changing the stage architecture from a rotary design to a linear design that can still meet the throughput requirements but with more conventional technology that entails less technical risk. The linear concept also allows for simplifications in the datapath, primarily from being able to reuse pattern data across dies and columns. Finally, we are now able to demonstrate working dynamic pattern generator (DPG) chips, CMOS chips with microfabricated lenslets on top to prevent crosstalk between pixels.

  20. Recent progress in the joint multisensor mine-signatures database project

    NASA Astrophysics Data System (ADS)

    Lewis, Adam M.; Verlinde, Patrick S. A.; Acheroy, Marc P. J.; Sieber, Alois J.

    2002-08-01

    The MsMs project is a major campaign to collect calibrated and well-documented data, suitable for use by workers developing advanced multisensor algorithms for antipersonnel mine detection. The data, together with a full description of the site layout and measurement protocols, are publicly available via the internet site http://demining.jrc.it/msms. Measurements are made on a test lane consisting of 7 plots of different soils, each 6m by 6m, populated with surrogate mines, calibration objects, simulated clutter and position markers. There are 48 targets in each plot, configured identically for all plots. A first report was presented last year. Since then, laser acoustic vibrometer and magnetometer data have been added and the metal detector and thermal infrared data have been augmented. The database has been reformatted to make it more uniform and user-friendly and to remove typographic mistakes. The test site remains essentially unchanged, apart from some equipment upgrades, and is available for further data collection. In particular, the targets have not been moved, so as to provide stable surrounding soil conditions representative of mines left undisturbed for long periods post-conflict. This presentation will describe the new data and data format, the status of the upgrades and the outlook for the future.

  1. NREL Solar Radiation Resource Assessment Project: Status and outlook. FY 1991 annual progress report

    SciTech Connect

    Renne, D.; Riordan, C.; Maxwell, E.; Stoffel, T.; Marion, B.; Rymes, M.; Wilcox, S.; Myers, D.

    1992-05-01

    This report summarizes the activities and accomplishments of NREL`s Solar Radiation Resource Assessment Project during fiscal year 1991. Currently, the primary focus of the SRRAP is to produce a 1961--1990 National Solar Radiation Data Base, providing hourly values of global horizontal, diffuse, and direct normal solar radiation at approximately 250 sites around the United States. Because these solar radiation quantities have been measured intermittently at only about 50 of these sites, models were developed and applied to the majority of the stations to provide estimates of these parameters. Although approximately 93% of the data base consists of modeled data this represents a significant improvement over the SOLMET/ERSATZ 1952--1975 data base. The magnitude and importance of this activity are such that the majority of SRRAP human and financial in many other activities, which are reported here. These include the continued maintenance of a solar radiation monitoring network in the southeast United States at six Historically Black Colleges and Universities (HBCU`s), the transfer of solar radiation resource assessment technology through a variety of activities, participation in international programs, and the maintenance and operation of NREL`s Solar Radiation Research Laboratory. 17 refs.

  2. Progress with the 2Q-LEBT facility for the RIA project.

    SciTech Connect

    Vinogradov, N.; Aseev, V. N.; Kern, M. R. L.; Ostroumov, P. N.; Pardo, R. C.; Scott, R.; Physics

    2005-01-01

    The design goal of 400 kW uranium beam in the Rare Isotope Accelerator (RIA) Driver Linac can be achieved employing a concept of simultaneous acceleration of two charge states. It has been undertaken to build a prototype 2Q-injector of the RIA Driver Linac which includes an ECR ion source, a LEBT and one-segment of the prototype RFQ. The project called the 2Q-LEBT Facility is being developed in the Physics Division of ANL. Currently, the 2Q-LEBT Facility consists of BIE-100 ECR ion source. The reassembly and commissioning of the source has been completed. During the commissioning process we redesigned and manufactured a few components of the source to increase the beam production performance. A new diagnostic station has been designed and built for accurate measurements of the output beam emittance. The further development of the 2Q-LEBT Facility comprises installation of the source on 100 kV high-voltage platform, building an achromatic bending and transport system including the multi-harmonic buncher, and a full power 57.5 MHz RFQ segment. This report includes a detailed description of the 2Q-LEBT design and beam dynamics simulations along with emittance measurements for various beams.

  3. NERI Project 99-119. A New Paradigm for Automatic Development of Highly Reliable Control Architectures for Nuclear Power Plants. Phase-2 Progress Report

    SciTech Connect

    March-Leuba, JA

    2002-01-15

    This report describes the tasks performed and the progress made during Phase 2 of the DOE-NERI project number 99-119 entitled Automatic Development of Highly Reliable Control Architecture for Future Nuclear Power Plants. This project is a collaboration effort between the Oak Ridge National Laboratory (ORNL), The University of Tennessee, Knoxville (UTK) and the North Carolina State University (NCSU). ORNL is the lead organization and is responsible for the coordination and integration of all work.

  4. Ground-water monitoring compliance projects for Hanford Site Facilities: Progress report for the period April 1--June 30, 1988: Volume 1, Text

    SciTech Connect

    Not Available

    1988-09-01

    This is Volume 1 of a two-volume set of documents that describes the progress of 10 Hanford Site ground-water monitoring projects for the period April 1 to June 30, 1988. This volume discusses the projects; Volume 2 provides as-built diagrams, drilling logs, and geophysical logs for wells drilled during this period in the 100-N Area and near the 216-A-36B Crib.

  5. The dynamics of mass migration

    PubMed Central

    Massey, Douglas S.; Zenteno, Rene M.

    1999-01-01

    We specify a set of equations defining a dynamic model of international migration and estimate its parameters by using data specially collected in Mexico. We then used it to project the a hypothetical Mexican community population forward in time. Beginning with a stable population of 10,000 people, we project ahead 50 years under three different assumptions: no international migration; constant probabilities of in- and out-migration, and dynamic schedules of out- and in-migration that change as migratory experience accumulates. This exercise represents an attempt to model the self-feeding character of international migration noted by prior observers and theorists. Our model quantifies the mechanisms of cumulative causation predicted by social capital theory and illustrates the shortcomings of standard projection methodologies. The failure to model dynamically changing migration schedules yields a 5% overstatement of the projected size of the Mexican population after 50 years, an 11% understatement of the total number of U.S. migrants, a 15% understatement of the prevalence of U.S. migratory experience in the Mexican population, and an 85% understatement of the size of the Mexican population living in the United States. PMID:10220465

  6. Snake River Sockeye Salmon Captive Broodstock Program Hatchery Element : Project Progress Report 2007 Annual Report.

    SciTech Connect

    Baker, Dan J.; Heindel, Jeff A.; Green, Daniel G.; Kline, Paul A.

    2008-12-17

    Numbers of Snake River sockeye salmon Oncorhynchus nerka have declined dramatically in recent years. In Idaho, only the lakes of the upper Salmon River (Sawtooth Valley) remain as potential sources of production (Figure 1). Historically, five Sawtooth Valley lakes (Redfish, Alturas, Pettit, Stanley, and Yellowbelly) supported sockeye salmon (Bjornn et al. 1968; Chapman et al. 1990). Currently, only Redfish Lake receives a remnant anadromous run. On April 2, 1990, the National Oceanic and Atmospheric Administration Fisheries Service (NOAA - formerly National Marine Fisheries Service) received a petition from the Shoshone-Bannock Tribes (SBT) to list Snake River sockeye salmon as endangered under the United States Endangered Species Act (ESA) of 1973. On November 20, 1991, NOAA declared Snake River sockeye salmon endangered. In 1991, the SBT, along with the Idaho Department of Fish & Game (IDFG), initiated the Snake River Sockeye Salmon Sawtooth Valley Project (Sawtooth Valley Project) with funding from the Bonneville Power Administration (BPA). The goal of this program is to conserve genetic resources and to rebuild Snake River sockeye salmon populations in Idaho. Coordination of this effort is carried out under the guidance of the Stanley Basin Sockeye Technical Oversight Committee (SBSTOC), a team of biologists representing the agencies involved in the recovery and management of Snake River sockeye salmon. National Oceanic and Atmospheric Administration Fisheries Service ESA Permit Nos. 1120, 1124, and 1481 authorize IDFG to conduct scientific research on listed Snake River sockeye salmon. Initial steps to recover the species involved the establishment of captive broodstocks at the Eagle Fish Hatchery in Idaho and at NOAA facilities in Washington State (for a review, see Flagg 1993; Johnson 1993; Flagg and McAuley 1994; Kline 1994; Johnson and Pravecek 1995; Kline and Younk 1995; Flagg et al. 1996; Johnson and Pravecek 1996; Kline and Lamansky 1997; Pravecek and

  7. Migration Theories

    NASA Astrophysics Data System (ADS)

    Crida, Aurélien

    2015-08-01

    The great variety of the architectures of the extra-solar planetary systems has revealed the fundamental role played by planetary migration: the interactions between the planets and the gaseous disk in which they form leads to a modification of their orbits. Here, I will review the basic processes and the most recent results in this area.Planets up to ~50 Earth masses are prone to so-called type I migration.I will describe the processes at play, namely the Lindblad and corotation torques, and explain how the total torque depends on the planet mass and the local disk structure. Application to realistic disks shows one or two sweet spot(s) for outward migration of planets roughly between 5 and 30 Earth masses around the snowline ; this is confirmed by dedicated 3D numerical simulations. This has strong consequences on the formation of hot Super-Earths or mini-Neptunes.For smaller mass planets, it has been recently proposed that the heating of the neighboring gas by the luminous planet can lead to a positive torque, hence promoting outward migration. On the other hand, if the planet is not a heat source, a cold finger appears, whose resulting torque is negative. Applications of these two recent results should be discussed.Giant planets open gaps in the proto-planetary disk, and then are supposedly subject to type II migration, following the viscous accretion of the disk. This standard picture has been questioned recently, as gas appears to drift through the gap. Although the gap opening process is well understood in 2D for a planet on a fixed orbit, recent results on 3D simulations or migrating planets make the picture more accurate.Our ever better understanding of planet-disk interactions is of crucial importance as the statistics on extra solar systems keep growing and the results of these interactions are now imaged.

  8. Migrating Planets

    NASA Astrophysics Data System (ADS)

    Murray, N.; Hansen, B.; Holman, M.; Tremaine, S.

    1998-01-01

    A planet orbiting in a disk of planetesimals can experience an instability in which it migrates to smaller orbital radii. Resonant interactions between the planet and planetesimals remove angular momentum from the planetesimals, increasing their eccentricities. Subsequently, the planetesimals either collide with or are ejected by the planet, reducing the semimajor axis of the planet. If the surface density of planetesimals exceeds a critical value, corresponding to 0.03 solar masses of gas inside the orbit of Jupiter, the planet will migrate inward a large distance. This instability may explain the presence of Jupiter-mass objects in small orbits around nearby stars.

  9. A progress report on the ARRA-funded geotechnical site characterization project

    NASA Astrophysics Data System (ADS)

    Martin, A. J.; Yong, A.; Stokoe, K.; Di Matteo, A.; Diehl, J.; Jack, S.

    2011-12-01

    calculated VS30 for each site-will be prepared after the completion of the project in November 2011.

  10. Enabling the direct detection of earth-sized exoplanets with the LBTI HOSTS project: a progress report

    NASA Astrophysics Data System (ADS)

    Danchi, W.; Bailey, V.; Bryden, G.; Defrère, D.; Ertel, S.; Haniff, C.; Hinz, P.; Kennedy, G.; Mennesson, B.; Millan-Gabet, R.; Rieke, G.; Roberge, A.; Serabyn, E.; Skemer, A.; Stapelfeldt, K.; Weinberger, A.; Wyatt, M.; Vaz, A.

    2016-08-01

    NASA has funded a project called the Hunt for Observable Signatures of Terrestrial Systems (HOSTS) to survey nearby solar type stars to determine the amount of warm zodiacal dust in their habitable zones. The goal is not only to determine the luminosity distribution function but also to know which individual stars have the least amount of zodiacal dust. It is important to have this information for future missions that directly image exoplanets as this dust is the main source of astrophysical noise for them. The HOSTS project utilizes the Large Binocular Telescope Interferometer (LBTI), which consists of two 8.4-m apertures separated by a 14.4-m baseline on Mt. Graham, Arizona. The LBTI operates in a nulling mode in the mid-infrared spectral window (8-13 μm), in which light from the two telescopes is coherently combined with a 180 degree phase shift between them, producing a dark fringe at the location of the target star. In doing so the starlight is greatly reduced, increasing the contrast, analogous to a coronagraph operating at shorter wavelengths. The LBTI is a unique instrument, having only three warm reflections before the starlight reaches cold mirrors, giving it the best photometric sensitivity of any interferometer operating in the mid-infrared. It also has a superb Adaptive Optics (AO) system giving it Strehl ratios greater than 98% at 10 μm. In 2014 into early 2015 LBTI was undergoing commissioning. The HOSTS project team passed its Operational Readiness Review (ORR) in April 2015. The team recently published papers on the target sample, modeling of the nulled disk images, and initial results such as the detection of warm dust around η Corvi. Recently a paper was published on the data pipeline and on-sky performance. An additional paper is in preparation on β Leo. We will discuss the scientific and programmatic context for the LBTI project, and we will report recent progress, new results, and plans for the science verification phase that started in

  11. Dateline Migration.

    ERIC Educational Resources Information Center

    Tomasi, Lydio E., Ed.

    1995-01-01

    Presents data on international migration and its effects in and between various countries in North America, Europe, and Africa. Discussions include refugee, immigrant, and migrant worker flows; the legal, political, and social problems surrounding immigrants; alien terrorism and law enforcement problems; and migrant effects on education, social…

  12. The Rise and Fall of the Social Science Curriculum Project in Iceland, 1974-1984: Reflections on Reason and Power in Educational Progress.

    ERIC Educational Resources Information Center

    Edelstein, Wolfgang

    1987-01-01

    Examines the demise of the Icelandic Social Science Curriculum Project (SSCP) as an example of progressive educational reform thwarted by neofundamentalist ideologies. States that the paper goes beyond Jerome Bruner's 1984 account of the rise and fall of "Man: A Course of Study" to provide a deeper analysis of the politics of…

  13. EXPERIMENTAL AND DEMONSTRATION MANPOWER PROJECT FOR TRAINING AND PLACEMENT OF YOUTHFUL INMATES OF DRAPER CORRECTIONAL CENTER, ELMORE, ALABAMA. 16TH PROGRESS REPORT, MAY 1-JULY 1, 1967.

    ERIC Educational Resources Information Center

    MCKEE, JOHN M.

    PROGRESS IN THE AREAS OF EMPLOYMENT, PUBLIC RELATIONS, THE CORRECTIONAL SYSTEM, COOPERATING AGENCIES, AND RECIDIVISM ARE ILLUSTRATED BY FOUR CASE STUDIES OF PAROLEE GRADUATES FROM THE CENTER'S EDUCATIONAL PROGRAM. OF THE 980 INMATES WHO APPLIED FOR TRAINING DURING 33 MONTHS OF PROJECT OPERATION, 271 COMPLETED TRAINING, AND 74 WERE PRESENTLY…

  14. Programmatic Research to Develop and Disseminate Improved Instructional Technology for Handicapped Children. Project MORE Quarterly Progress Report, September 1 to December 1, 1972.

    ERIC Educational Resources Information Center

    Schiefelbusch, Richard L.; Lent, James R.

    During the past reporting period the curriculum development staff of Project MORE (Mediated Operational Research for Education) has made substantial progress in attaining its program objectives. Design and development phases have proceeded on schedule. Four programs are currently in the field-testing stage, and four others are under development.…

  15. RECONSTRUCTION OF DOSE TO THE RESIDENTS OF OZERSK FROM THE OPERATION OF THE MAYAK PRODUCTION ASSOCIATION: 1948-2002: Progress Report on Project 1.4

    SciTech Connect

    Mokrov, Y.; Rovny, Sergey I.; Anspaugh, L. R.; Napier, Bruce A.

    2009-10-23

    This Progress Report for Project 1.4 of the U.S.–Russia Joint Coordinating Committee on Radiation Effects Research continues in the abbreviated format of providing details only on the work accomplished during this six-month reporting period.

  16. Six month progress report on the Waste Package Project at the University of Nevada, Las Vegas, July 1991--January 1992: Management, quality assurance and overview

    SciTech Connect

    Ladkany, S.G.

    1991-12-31

    The progress of the waste package project at the University of Nevada, Las Vegas was the subject of this report. It covered aspects of management and quality assurance, container design, application of ASME Pressure Vessel Codes, structural analysis of containers, design of rock tunnels for storage, and heat transfer phenomena. (MB)

  17. Six month progress report on the Waste Package Project at the University of Nevada, Las Vegas, July 1991--January 1992: Management, quality assurance and overview

    SciTech Connect

    Ladkany, S.G.

    1991-01-01

    The progress of the waste package project at the University of Nevada, Las Vegas was the subject of this report. It covered aspects of management and quality assurance, container design, application of ASME Pressure Vessel Codes, structural analysis of containers, design of rock tunnels for storage, and heat transfer phenomena. (MB)

  18. Project Catch-Up, June, 1966 to July, 1971: An Educational Program for Socially Disadvantaged Thirteen and Fourteen Year Old Youngsters. A Progress Report....

    ERIC Educational Resources Information Center

    Mason, Evelyn P.

    In this progress report are descriptions of (1) the 1970 program of Project Catch-Up (PCU), Western Washington State College's (WWSC) 6-week summer residence program of remediation and cultural enrichment for junior high age youth of ethnic minority status or poverty background having high potential and low achievement, and (2) the follow-up…

  19. Hydrologic Resources Management Program and Underground Test Area Project FY 2001-2002 Progress Report

    SciTech Connect

    Rose, T P; Kersting, A B; Harris, L J; Hudson, G B; Smith, D K; Williams, R W; Loewen, D R; Nelson, E J; Allen, P G; Ryerson, F J; Pawloski, G A; Laue, C A; Moran, J E

    2003-08-15

    This report contains highlights of FY 2001 and 2002 technical studies conducted by the Analytical and Nuclear Chemistry Division (ANCD) at Lawrence Livermore National Laboratory (LLNL) in support of the Hydrologic Resources Management Program (HRMP) and the Underground Test Area (UGTA) Project. These programs are administered by the U.S. Department of Energy, National Nuclear Security Administration, Nevada Site Office (NNSA/NSO) through the Defense Programs and Environmental Restoration Divisions, respectively. HRMP-sponsored work emphasizes the Defense Programs goal of responsible management of natural resources at the NTS, while UGTA-funded work focuses on defining the extent of radionuclide contamination in NTS groundwater resulting from underground nuclear testing. The report is organized on a topical basis, and contains eight chapters that reflect the range of technical work performed by LLNL-ANCD in support of HRMP and UGTA. Chapter 1 describes recent hot well sampling efforts at the NTS, and presents the results of chemical and isotopic analyses of groundwater samples from six near-field wells. These include the Cambric (UE-5n), Bilby (U-3cn PS No.2), Bourbon (UE-7nS), Nash (UE-2ce), Tybo/Benham (ER-20-5 No.3), and Almendro (U-19v PS No.1ds) sites. The data generated by the hot well program is vital to the development and validation of contaminant transport models at the NTS. Chapter 2 discusses the results of xenon isotope measurements of groundwater samples from the six near-field wells described in Chapter 1. This work demonstrates that fission xenon is present in the water at levels that are readily measurable and highlights the significant differences in xenon concentrations and isotopic abundances at different sites. These differences provide insight into the early cooling history of nuclear test cavities, and may assist in predicting the distribution of the source term in the near-field environment. Chapter 3 is an investigation of the distribution

  20. BX in situ oil shale project. Annual technical progress report, March 1, 1979-February 29, 1980 and quarterly technical progress report, December 1, 1979-February 29, 1980

    SciTech Connect

    Dougan, P.M.

    1980-03-20

    During the year, design, construction and installation of all project equipment was completed, and continuous steam injection began on September 18, 1979 and continued until February 29, 1980. In the five-month period of steam injection, 235,060 barrels of water as steam at an average wellhead pressure of 1199 psig and an average wellhead temperature of 456/sup 0/F were injected into the eight project injection wells. Operation of the project at design temperature and pressure (1000/sup 0/F and 1500 psig) was not possible due to continuing problems with surface equipment. Environmental monitoring at the project site continued during startup and operation.

  1. Decreased Expression of MiRNA-204-5p Contributes to Glioma Progression and Promotes Glioma Cell Growth, Migration and Invasion

    PubMed Central

    Xia, Zhiqiang; Liu, Fang; Zhang, Jian; Liu, Li

    2015-01-01

    Gliomas are the most common malignant primary brain tumors in adults and exhibit a spectrum of aberrantly aggressive phenotype. Although increasing evidence indicated that the deregulation of microRNAs (miRNAs) contributes to tumorigenesis and invasion, little is known about the roles of miR-204-5p in human gliomas. In the present study, the expression of miR-204-5p in clinical glioma tissues was measured by qRT-PCR. The effects of miR-204-5p on glioma cell growth and metastasis were examined by overexpressing or inhibiting miR-204-5p. We found that the expression level of miR-204-5p was significantly reduced in clinical glioma tissues compared with normal brain tissues. Moreover, we revealed that the introduction of miR-204-5p dramatically suppressed glioma cell growth, migration and invasion. Furthermore, mechanistic investigations revealed that RAB22A, a member of the RAS oncogene family, is a direct functional target of miR-204-5p in gliomas. In vivo, restoring miR-204-5p expression in glioma cells suppressed tumorigenesis and increased overall host survival. Our findings suggest that miR-204-5p is a cancer suppressor miRNA and overexpression of miR-204-5p is a novel glioma treatment strategy. PMID:26134825

  2. Monitor and Protect Wigwam River Bull Trout for Koocanusa Reservoir; White River Bull Trout Enumeration Project Summary, Progress Report 2003.

    SciTech Connect

    Cope, R.

    2004-02-01

    This report summarizes the first year of a three-year bull trout (Salvelinus confluentus) enumeration project on the White River and is a co-operative initiative of the British Columbia Ministry of Water, Land, and Air Protection and Bonneville Power Administration. The White River has been identified as an important bull trout spawning tributary of the upper Kootenay River in southeastern British Columbia. The objective was to collect information on the returning adult spawning population to the White River through the use of a fish fence and traps, and to conduct redd surveys at the conclusion of spawning to provide an index of spawning escapement and distribution. The fence was installed on September 9th, 2003 and was operated continuously (i.e. no high-water or breaching events) until the fence was removed on October 9th, 2003. Estimation of the spawning population of White River bull trout was incomplete. This was due to a larger and more protracted out-migration than expected. As a result, the bull trout spawning population of the White River was estimated to be somewhere above 899 fish. In comparison, this represents approximately one third the population estimate of the 2003 Wigwam River bull trout spawning population. Based on redd index data, the number of bull trout per redd was over twice that of the Wigwam River or Skookumchuck Creek. This was expected as the index sites on the Wigwam River and Skookumchuck Creek cover the majority of the spawning area. This is not true on the White River. From previous redd counts, it is known that there are approximately twice as many redds in Blackfoot Creek as there are in the index site. Additionally, given the large size of the White River watershed and in particular, the large number of tributaries, there is a high likelihood that important bull trout spawning areas remain unidentified. Both floy tag and radio-telemetry data for the White River bull trout have identified extensive life history migrations

  3. The combined use of Building Information Modelling (BIM) and Unmanned Aerial Vehicle (UAV) technologies for the 3D illustration of the progress of works in infrastructure construction projects

    NASA Astrophysics Data System (ADS)

    Vacanas, Yiannis; Themistocleous, Kyriacos; Agapiou, Athos; Hadjimitsis, Diofantos

    2016-08-01

    Building Information Modelling (BIM) technology is already part of the construction industry and is considered by professionals as a very useful tool for all phases of a construction project. BIM technology, with the particularly useful 3D illustrations which it provides, can be used to illustrate and monitor the progress of works effectively through the entire lifetime of the project. Unmanned Aerial Vehicles (UAVs) have undergone significant advances in equipment capabilities and now have the capacity to acquire high resolution imagery from different angles in a cost effective and efficient manner. By using photogrammetry, characteristics such as distances, areas, volumes, elevations, object sizes, and object shape can be determined within overlapping areas. This paper explores the combined use of BIM and UAV technologies in order to achieve efficient and accurate as-built data collection and 3D illustrations of the works progress during an infrastructure construction project.

  4. Progress report for the project: Comparison of the response of mature branches and seedlings of Pinus ponderosa to atmospheric pollution

    SciTech Connect

    Houpis, J.L.J.; Anderson, P.D.; Benes, S.E.; Phelps, S.P.; Loeffler, A.T.

    1990-09-01

    This progress report details Lawrence Livermore National Laboratory's (LLNL) performance regarding the projects Comparison of the Response of Mature Branches and Seedlings of Pinus ponderosa to Atmospheric Pollution'' and Effects of Ozone, acid Precipitation, and Their Interactions on Mature Branches and Seedlings of Ponderosa Pine'' for the months of November 1989 to June 1990. During the last eight months, we have initiated ozone and acid precipitation exposures, and we began intensive growth, morphological, and physiological measurements. During these major physiological measurement periods, we measured photosynthesis, transpiration, stomatal conductance, respiration, antioxidant activity, pigmentation, and foliar nutrient concentration. We have also concluded the analysis of our branch autonomy experiment, which we conducted in the fall. We determined that virtually no carbon is exported among branches in close proximity to one another. This conclusion assists in validating the approach of using branches and branch exposure chambers as a means of assessing the effects of air pollution on mature trees of Ponderosa pine. 6 refs., 4 figs., 3 tabs.

  5. Guidance for growth factors, projections, and control strategies for the 15 percent rate-of-progress plans

    SciTech Connect

    Not Available

    1993-03-01

    Section 182(b)(1) of the Clean Air Act (Act) requires all ozone nonattainment areas classified as moderate and above to submit a State Implementation Plan (SIP) revision by November 15, 1993, which describes, in part, how the areas will achieve an actual volatile organic compound (VOC) emissions reduction of at least 15 percent during the first 6 years after enactment of the Clean Air Act Amendments of 1990 (CAAA). In addition, the SIP revision must describe how any growth in emissions from 1990 through 1996 will be fully offset. It is important to note that section 182(b)(1) also requires the SIP for moderate areas to provide for reductions in VOC and nitrogen oxides (NOx) emissions as necessary to attain the national primary ambient air quality standard for ozone by November 15, 1996. The guidance document focuses on the procedures for developing 1996 projected emissions inventories and control measures which moderate and above ozone nonattainment areas must include in their rate-of-progress plans. The document provides technical guidance to support the policy presented in the 'General Preamble: Implementation of Title I of the CAAA of 1990' (57 FR 13498).

  6. Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT): Rationale and design of a meta-analysis project.

    PubMed

    Lorenz, Matthias W; Bickel, Horst; Bots, Michiel L; Breteler, Monique M B; Catapano, Alberico L; Desvarieux, Moise; Hedblad, Bo; Iglseder, Bernhard; Johnsen, Stein Harald; Juraska, Michal; Kiechl, Stefan; Mathiesen, Ellisiv B; Norata, Giuseppe D; Grigore, Liliana; Polak, Joseph; Poppert, Holger; Rosvall, Maria; Rundek, Tatjana; Sacco, Ralph L; Sander, Dirk; Sitzer, Matthias; Steinmetz, Helmuth; Stensland, Eva; Willeit, Johann; Witteman, Jacqueline; Yanez, David; Thompson, Simon G

    2010-05-01

    Carotid intima media thickness (IMT) progression is increasingly used as a surrogate for vascular risk. This use is supported by data from a few clinical trials investigating statins, but established criteria of surrogacy are only partially fulfilled. To provide a valid basis for the use of IMT progression as a study end point, we are performing a 3-step meta-analysis project based on individual participant data. Objectives of the 3 successive stages are to investigate (1) whether IMT progression prospectively predicts myocardial infarction, stroke, or death in population-based samples; (2) whether it does so in prevalent disease cohorts; and (3) whether interventions affecting IMT progression predict a therapeutic effect on clinical end points. Recruitment strategies, inclusion criteria, and estimates of the expected numbers of eligible studies are presented along with a detailed analysis plan.

  7. Contracts for field projects and supporting research on enhanced oil recovery. Progress review No. 78, quarter ending March 31, 1994

    SciTech Connect

    1995-05-01

    This report presents descriptions of various research projects and field projects concerned with the enhanced recovery of petroleum. Contract numbers, principal investigators, company names, and project management information is included.

  8. What's driving migration?

    PubMed

    Kane, H

    1995-01-01

    During the 1990s investment in prevention of international or internal migration declined, and crisis intervention increased. The budgets of the UN High Commissioner for Refugees and the UN Development Program remained about the same. The operating assumption is that war, persecution, famine, and environmental and social disintegration are inevitable. Future efforts should be directed to stabilizing populations through investment in sanitation, public health, preventive medicine, land tenure, environmental protection, and literacy. Forces pushing migration are likely to increase in the future. Forces include depletion of natural resources, income disparities, population pressure, and political disruption. The causes of migration are not constant. In the past, migration occurred during conquests, settlement, intermarriage, or religious conversion and was a collective movement. Current migration involves mass movement of individuals and the struggle to survive. There is new pressure to leave poor squatter settlements and the scarcities in land, water, and food. The slave trade between the 1500s and the 1800s linked continents, and only 2-3 million voluntarily crossed national borders. Involuntary migration began in the early 1800s when European feudal systems were in a decline, and people sought freedom. Official refugees, who satisfy the strict 1951 UN definition, increased from 15 million in 1980 to 23 million in 1990 but remained a small proportion of international migrants. Much of the mass movement occurs between developing countries. Migration to developed countries is accompanied by growing intolerance, which is misinformed. China practices a form of "population transfer" in Tibet in order to dilute Tibetan nationalism. Colonization of countries is a new less expensive form of control over territory. Eviction of minorities is another popular strategy in Iraq. Public works projects supported by foreign aid displace millions annually. War and civil conflicts

  9. Project progress report

    SciTech Connect

    Isakov, A. I.

    1997-12-31

    Works of two variety have been fulfilled: first, research of polystyrene shells formation conditions in drop tower furnace and ballistic furnace; second, creation of computer codes for simulation of shells formation processes, including numerous nucleation. Besides that polystyrene shells with diameter up to 2 mm transmitted to LLNL in parcel.

  10. Simple rules guide dragonfly migration

    PubMed Central

    Wikelski, Martin; Moskowitz, David; Adelman, James S; Cochran, Jim; Wilcove, David S; May, Michael L

    2006-01-01

    Every year billions of butterflies, dragonflies, moths and other insects migrate across continents, and considerable progress has been made in understanding population-level migratory phenomena. However, little is known about destinations and strategies of individual insects. We attached miniaturized radio transmitters (ca 300 mg) to the thoraxes of 14 individual dragonflies (common green darners, Anax junius) and followed them during their autumn migration for up to 12 days, using receiver-equipped Cessna airplanes and ground teams. Green darners exhibited distinct stopover and migration days. On average, they migrated every 2.9±0.3 days, and their average net advance was 58±11 km in 6.1±0.9 days (11.9±2.8 km d−1) in a generally southward direction (186±52°). They migrated exclusively during the daytime, when wind speeds were less than 25 km h−1, regardless of wind direction, but only after two nights of successively lower temperatures (decrease of 2.1±0.6 °C in minimum temperature). The migratory patterns and apparent decision rules of green darners are strikingly similar to those proposed for songbirds, and may represent a general migration strategy for long-distance migration of organisms with high self-propelled flight speeds. PMID:17148394

  11. Quarterly progress report on the DOE Waste Package project at the University of Nevada, Las Vegas, July 1, 1993 through September 30, 1993

    SciTech Connect

    Ladkany, S.G.

    1993-11-01

    Progress reports are presented for the following tasks: overview and progress of waste package project and container design; waste container design considerations (criticality analysis, experimental drift model); waste container alternate design considerations; thermal simulation of high level nuclear waste canister emplacement; structural analysis and design of nuclear waste package canister; robotic manipulation of the nuclear waste container; investigation of stress in a circular tunnel due to overburden & thermal loading of horizontally placed 21PWR multi-purpose canisters; investigation of faulted tunnel models by combined photoelasticity and finite element analysis; and transport phenomena in the near field.

  12. Initiatives for community building in an urban semi-marginal village: Progress of the Ajinadai Lively Project and future challenges.

    PubMed

    Masaki, Naoko; Matsubara, Miyuki; Hayashi, Shinji; Fukuizumi, Maiko; Morimoto, Chiyoko; Mori, Matsue

    2016-01-01

    Objectives We launched and engaged in the "Ajinadai Lively Project" to examine the ideal state of community building in an urban semi-marginal village. In addition to discussing its progress and describing the activities, we examine future challenges.Methods (1) We gathered existing resources, conducted a district survey and focus group interview, and investigated the community's health issues. (2) We conducted a workshop with local residents and formulated an action plan. (3) We conducted a health volunteer training class to foster community leaders. (4) Local residents interacted with students through nursing school practice and student volunteer activities.Results The health issues in the community were as follows: (1) Few connections existed between residents across generations, and no framework for mutual assistance was established. (2) Many solitary elderly people and elderly households existed, and we found many instances of elderly-to-elderly care and social withdrawal of elderly people. (3) Many slopes and staircases existed, which made mobility difficult for elderly people. Based on these results, we encouraged the state to pursue quality of life as "A community where people connect and help one another across generations" as well as "A healthy community where people greet one another." We also established health, behavioral, and environmental goals. The health volunteer training class became an impetus for residents to realize the necessity of not only protecting their own health, but also encouraging others and the whole community to get involved.Conclusion While the health volunteer training class did not initiate autonomous activity, it increased the motivation of residents themselves for community building. Performing continuous evaluations and offering support for autonomous activity is important in the future.

  13. Assessing fish predation on migrating juvenile steelhead and a retrospective comparison to steelhead survival through the Priest Rapids Hydroelectric Project, Columbia River, Washington, 2009-11

    USGS Publications Warehouse

    Hardiman, Jill M.; Counihan, Timothy D.; Burgess, Dave S.; Simmons, Katrina E.; Holmberg, Glen S.; Rogala, Josh; Polacek, Rochelle

    2012-01-01

    The U.S. Geological Survey (USGS) and the Washington Department of Fish and Wildlife (WDFW) have been working with the Public Utility District No. 2 of Grant County, Washington (Grant PUD), to increase their understanding of predator-prey interactions in the Priest Rapids Hydroelectric Project (PRP), Columbia River, Washington. For this study, the PRP is defined as the area approximately 6 kilometers upstream of Wanapum Dam to the Priest Rapids Dam tailrace, 397.1 miles from the mouth of the Columbia River. Past year’s low survival numbers of juvenile steelhead (Oncorhynchus mykiss) through Wanapum and Priest Rapids Dams has prompted Grant PUD, on behalf of the Priest Rapids Coordinating Committee, to focus research efforts on steelhead migration and potential causal mechanisms for low survival. Steelhead passage survival in 2009 was estimated at 0.944 through the Wanapum Development (dam and reservoir) and 0.881 through the Priest Rapids Development and for 2010, steelhead survival was 0.855 for Wanapum Development and 0.904 for Priest Rapids Development. The USGS and WDFW implemented field collection efforts in 2011 for northern pikeminnow (Ptychocheilus oregonensis), smallmouth bass (Micropterus dolomieu), and walleye (Sander vitreus, formerly Stizostedion vitreum) and their diets in the PRP. For predator indexing, we collected 948 northern pikeminnow, 237 smallmouth bass, 18 walleye, and two largemouth bass (Micropterus salmoides). The intent of this study was to provide standardized predation indices within individual reaches of the PRP to discern spatial variability in predation patterns. Furthermore, the results of the 2011 study were compared to results of a concurrent steelhead survival study. Our results do not indicate excessively high predation of Oncorhynchus spp. occurring by northern pikeminnow or smallmouth bass in any particular reach throughout the study area. Although we found Oncorhynchus spp. in the predator diets, the relative

  14. Resource conservation and recovery act ground-water monitoring projects for Hanford facilities: Progress report for the period July 1 to September 30, 1988: Volume 2, Appendices

    SciTech Connect

    Fruland, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-02-01

    This is Volume 2 of a two-volume set of documents that describes the progress of 12 Hanford Site ground-water monitoring projects for the period July 1 to September 30, 1988. This volume provides those drilling logs and well inspection/completion reports inadvertently left out of last quarter's report for the 216-A-36B Crib (Appendix A) and as-built diagrams, drilling logs, and geophysical logs for wells drilled this quarter near the 2101-M Pond. Volume 1 discusses the 12 projects.

  15. Ground-water monitoring compliance projects for Hanford Site facilities: Progress report for the period April 1 to June 30, 1988: Volume 2, Appendices

    SciTech Connect

    Not Available

    1988-09-01

    This is Volume 2 of a two-volume set of documents that describes the progress of 10 Hanford Site ground-water monitoring projects for the period April 1 to June 30, 1988. This volume discusses as-built diagrams, drilling logs, and geophysical logs for wells drilled during this period in the 100-N Area (Appendix A) and near the 216-A-36B Crib (Appendix B). Volume 1 discusses the 10 projects. This work was supported by the US Department of Energy under Contract AC06-76RL01830.

  16. Resource Conservation and Recovery Act ground-water monitoring projects for Hanford facilities: Progress report for the period October 1 to December 31, 1989

    SciTech Connect

    Smith, R.M.; Bates, D.J.; Lundgren, R.E.

    1990-03-01

    This is Volume 1 of a two-volume document that describes the progress of 15 Hanford Site ground-water monitoring projects for the period October 1 to December 31, 1989. This volume discusses the projects. The work described in this document is conducted by the Pacific Northwest Laboratory under the management of Westinghouse Hanford Company for the US Department of Energy. Concentrations of ground-water constituents are compared to federal drinking water standards throughout this document for reference purposes. All drinking water supplied from the samples aquifer meets regulatory standards for drinking water quality. 51 refs., 35 figs., 86 tabs.

  17. Ground-water monitoring compliance projects for Hanford Site facilities: Volume 1, The report and Appendix A, Progress report for the period October 1 to December 31, 1986

    SciTech Connect

    Not Available

    1987-02-01

    This report documents recent progress on ground-water monitoring projects for four Hanford Site facilities: the 300 Area Process Trenches, the 183-H Solar Evaporation Basins, the 200 Area Low-Level Burial Grounds, and the Nonradioactive Dangerous Waste (NRDW) Landfill. The existing ground-water monitoring projects for the first two facilities named in the paragraph above are currently being expanded by adding new wells to the networks. During the reporting period, sampling of the existing wells continued on a monthly basis, and the analytical results for samples collected from September through November 1986 are included and discussed in this document. 8 refs., 41 figs., 7 tabs.

  18. High shear flow induces migration of adherent human platelets.

    PubMed

    Kraemer, Bjoern F; Schmidt, Christine; Urban, Benjamin; Bigalke, Boris; Schwanitz, Laura; Koch, Miriam; Seizer, Peter; Schaller, Martin; Gawaz, Meinrad; Lindemann, Stephan

    2011-01-01

    Shear forces are generated in all parts of the vascular system and contribute directly and indirectly to vascular disease progression. Endothelial cells are able to adapt to flow conditions, and are known to polarize and migrate in response to shear forces. Platelets exposed to shear stress are activated and release bioactive molecules from their alpha granules. So far, platelets have been considered to be static cells that do not leave the site of tight adhesion. However, we have recently been able to demonstrate the capacity of platelets to migrate in response to stromal derived factor-1 (SDF-1). In this project, we have demonstrated that platelets accumulate in areas with a high concentration of SDF-1 under flow conditions and respond to high shear stress by cellular polarization, cytoskeletal reorganisation, and flow-directed migration. In this context, we have shown increased Wiskott-Aldrich Syndrome protein (WASP) phosphorylation and intracellular redistribution of focal adhesion kinase (FAK) under high-shear stress conditions. The effect of flow-induced platelet migration has not previously been recognized and offers a new role for platelets as mobile cells. Their migratory potential may enable platelets to cover intimal lesions and contribute to vascular repair.

  19. Great Plains Coal Gasification Project: Quarterly technical progress report, April-June 1988 (Fourth fiscal quarter, 1987-1988)

    SciTech Connect

    Not Available

    1988-07-29

    This progress report describes the operation of the Great Plains Gasification Plant, including lignite coal production, SNG production, gas quality, by-products, and certain problems encountered. (LTN)

  20. Research-Airplane-Committee Report on Conference on the Progress of the X-15 Project : A Compilation of the Papers Presented

    NASA Technical Reports Server (NTRS)

    1958-01-01

    This document is a compilation of papers presented at the Conference on the Progress of the X-15 project held at the IAS Building, Los Angeles, California, July 28-30, 1958. The conference was held by the Research Airplane Committee of the U. S. Air Force, the U. S. Navy, and the National Advisory Committee for Aeronautics to report on the technical status of this airplane.

  1. Smolt Migration Characteristics and Mainstem Snake and Columbia River Detection Rates of PIT-Tagged Grande Ronde and Imnaha River Naturally Produced Spring Chinook Salmon, Annual Reports 1993, 1994, 1995 : Fish Research Project, Oregon.

    SciTech Connect

    Walters, Timothy R.; Carmichael, Richard W.; Keefe, MaryLouise

    1996-04-01

    This reports on the second, third, and fourth years of a multi-year study to assess smolt migration characteristics and cumulative detection rates of naturally produced spring chinook salmon (Oncorhynchus tshawytscha) from Northeast Oregon streams. The goal of this project is to develop an understanding of interpopulational and interannual variation in several early life history parameters of naturally produced spring and summer chinook salmon in the Grande Ronde and Imnaha River subbasins. This project will provide information to assist chinook salmon population recovery efforts. Specific populations included in the study are: (1) Catherine Creek; (2) Upper Grande Ronde River; (3) Lostine River; (4) Imnaha River; (5) Wenaha River; and (6) Minam River. In this document, the authors present findings and activities from research completed in 1993, 1994, and 1995.

  2. MIGRANT HEALTH PROJECT, PENNSYLVANIA, 1966--ANNUAL PROGRESS REPORT REPORT ON HEALTH AND MEDICAL SERVICES FOR MIGRANTS, PROJECT GRANT 33, UNITED STATES PUBLIC HEALTH SERVICE.

    ERIC Educational Resources Information Center

    CHAPMAN, A.L.; AND OTHERS

    HEALTH SERVICES WERE MADE AVAILABLE TO SOME 6176 SEASONAL AGRICULTURAL MIGRANTS IN A FIFTEEN-COUNTY PROJECT AREA OF PENNSYLVANIA DURING 1966. THIS PROJECT IS AN EXTENSION AND EXPANSION OF A FOUR-COUNTY MIGRANT HEALTH PROGRAM BEGUN IN 1963. THE SERVICES PROVIDED BY THIS PROGRAM HAVE BEEN EXPANDED FROM OUT-PATIENT SERVICES TO INCLUDE DENTAL CARE,…

  3. Migrating Legacy Systems in the Global Merger & Acquisition Environment

    ERIC Educational Resources Information Center

    Katerattanakul, Pairin; Kam, Hwee-Joo; Lee, James J.; Hong, Soongoo

    2009-01-01

    The MetaFrame system migration project at WorldPharma, while driven by merger and acquisition, had faced complexities caused by both technical challenges and organizational issues in the climate of uncertainties. However, WorldPharma still insisted on instigating this post-merger system migration project. This project served to (1) consolidate the…

  4. Asotin Creek Instream Habitat Alteration Projects : Habitat Evaluation, Adult and Juvenile Habitat Utilization and Water Temperature Monitoring : 2001 Progress Report.

    SciTech Connect

    Bumgarner, Joseph D.

    2002-01-01

    projects to improve fish habitat. In 1998, the ACCD identified the need for a more detailed analysis of these instream projects to fully evaluate their effectiveness at improving fish habitat. Therefore, ACCD contracted with WDFW's Snake River Lab (SRL) to take pre- and post-construction measurements of the habitat (i.e., pools, LOD, width, depth) at each site, and to evaluate fish use within some of the altered sites. These results have been published annually as progress reports to the ACCD (Bumgarner et al. 1999, Wargo et al. 2000, and Bumgarner and Schuck 2001). The ACCD also contracted with the WDFW SRL to conduct other evaluation and monitoring in the stream such as: (1) conduct snorkel surveys at habitat alteration sites to document fish usage following construction, (2) deploy temperature monitors throughout the basin to document summer water temperatures, and (3) attempt to document adult fish utilization by documenting the number of steelhead redds associated with habitat altered areas. This report provides a summary of pre-construction measurements taken on three proposed Charley Creek habitat sites during 2001, two sites in main Asotin Creek, and one site in George Creek, a tributary that enters in the lower Asotin Creek basin. Further, it provides a comparison of measurements taken pre- and post-construction on three 1999 habitat sites taken two years later, but at similar river flows. It also presents data collected from snorkel surveys, redd counts, and temperature monitoring.

  5. Characterization of Collective Cell Migration Dynamics

    NASA Astrophysics Data System (ADS)

    Lee, Rachel; Yue, Haicen; Rappel, Wouter-Jan; Losert, Wolfgang

    2015-03-01

    During cancer progression, tumor cells invade the surrounding tissue and migrate throughout the body, forming clinically dangerous secondary tumors. This metastatic process begins when cells leave the primary tumor, either as individual cells or collectively migrating groups. Here we present data on the migration dynamics of epithelial sheets composed of many cells. Using quantitative image analysis techniques, we are able to extract motion information from time-lapse images of cell lines with varying malignancy. Adapting metrics originally used to study fluid flows we are able to characterize the migration dynamics of these cell lines. By describing the migration dynamics in great detail, we are able to make a clear comparison of our results to a simulation of collective cell migration. Specifically, we explore whether leader cells are required to describe our expanding sheets of cells and whether the answer depends on individual cell activity.

  6. Progress in evaluation of radionuclide geochemical information developed by DOE high-level nuclear waste repository site projects; Report for October 1987--June 1989

    SciTech Connect

    Meyer, R.E.; Arnold, W.D.; O`Kelley, G.D.; Case, F.I.; Land, J.F.

    1989-08-01

    Information that is being developed by projects within the Department of Energy (DOE) pertinent to the potential geochemical behavior of radionuclides at candidate sites for a high-level radioactive waste repository is being evaluated by Oak Ridge National Laboratory (ORNL) for the Nuclear Regulatory Commission (NRC). During this report period, all experiments were conducted with tuff from the proposed high-level nuclear waste site at Yucca Mountain, Nevada. The principal emphasis in this report period was on column studies of migration of uranium and technetium in water from well J-13 at the Yucca Mountain site. Columns 1 cm in diameter and about 5 cm long were constructed and carefully packed with ground tuff. The characteristics of the columns were tested by determination of elution curves of tritium and TcO{sub 4}{sup {minus}}. Elution peaks obtained in past studies with uranium were asymmetrical and the shapes were often complex, observations that suggested irreversibilities in the sorption reaction. To try to understand these observations, the effects of flow rate and temperature on uranium migration were studied in detail. Sorption ratios calculated from the elution peaks became larger as the flow rate decreased and as the temperature increased. These observations support the conclusion that the sorption of uranium is kinetically hindered. To confirm this, batch sorption ratio experiments were completed for uranium as a function of time for a variety of conditions.

  7. News & Views Evaluation of Projects for Basic Research of Scientific Instruments in 2008 Completed NSFC Former President Tang Ao-qing Passed Away Professor Tang Aoqing and NSFC Carbon Nanotube Film-Based Speaker Developed in Tsinghua University Dinosaur Footprint Fossils Discovered in Xinjiang New Method for Early Cancer Diagnosis New Progress Achieved by NSFC Project in Basic Research of Black Hole Physics New progress in Organic FET 67 NSFC-RFBR Cooperative Projects Approved for 2008 Spin Configuration and Super-exchange Mechanism in Molecular Magnets Observed NSFC Strengthens its Funding in Wenchuan Concerns Go to Disaster's Impact on Economy and Emergency Response Thirty-seven NSFC-KOSEF Cooperative Projects Approved

    NASA Astrophysics Data System (ADS)

    2008-01-01

    Evaluation of Projects for Basic Research of Scientific Instruments in 2008 Completed NSFC Former President Tang Ao-qing Passed Away Professor Tang Aoqing and NSFC Carbon Nanotube Film-Based Speaker Developed in Tsinghua University Dinosaur Footprint Fossils Discovered in Xinjiang New Method for Early Cancer Diagnosis New Progress Achieved by NSFC Project in Basic Research of Black Hole Physics New progress in Organic FET 67 NSFC-RFBR Cooperative Projects Approved for 2008 Spin Configuration and Super-exchange Mechanism in Molecular Magnets Observed NSFC Strengthens its Funding in Wenchuan Concerns Go to Disaster's Impact on Economy and Emergency Response Thirty-seven NSFC-KOSEF Cooperative Projects Approved

  8. Logical Operations Instruction in the Preschool. Interim Progress Report - Hatch Research Project 142-1769, March, 1973.

    ERIC Educational Resources Information Center

    Burke-Merkle, Ann M.; And Others

    The original task of this project, the development of a preschool curriculum based on Piagetian theory, was broadened to include the development of a teacher training program supporting the curriculum. During the first year of the project the following has been accomplished: (1) a coded card file of approximately 100 curriculum-specific…

  9. A Smooth Trajectory: Developing Continuity and Progression between Primary and Secondary Science Education through a Jointly-Planned Projectiles Project

    ERIC Educational Resources Information Center

    Davies, Dan; McMahon, Kendra

    2004-01-01

    This article reports on findings from a two-year project--'Improving Science Together'--undertaken in 20 primary and four secondary schools in and around Bristol, UK. The project was funded by the pharmaceutical company AstraZeneca PLC as part of their national Science Teaching Trust initiative, and had as one of its aims the development of…

  10. Williams Holding Lease Steamflood Demonstration Project: Cat Canyon Oil Field. Third progress report, July 1978-November 1979

    SciTech Connect

    Ditmore, T.L.

    1980-06-01

    This report discusses pilot operations and results during this period. The performance of the displacement steam generator, the status of the sulfur dioxide scrubbing system, well workovers and the results of drilling four thermal observation wells are examined. Additional computer thermal simulation studies are discussed in detail and a new production performance projection is made. Finally, project economics and future operations are summarized.

  11. Recent progress in Open Data production and consumption - examples from a Governmental institute (SMHI) and a collaborative EU research project (SWITCH-ON)

    NASA Astrophysics Data System (ADS)

    Arheimer, Berit; Falkenroth, Esa

    2014-05-01

    The Swedish Meteorological and Hydrological Institute (SMHI) has a long tradition both in producing and consuming open data on a national, European and global scale. It is also promoting community building among water scientists in Europe by participating in and initiating collaborative projects. This presentation will exemplify the contemporary European movement imposed by the INSPIRE directive and the Open Data Strategy, by showing the progress in openness and shift in attitudes during the last decade when handling Research Data and Public Sector Information at a national European institute. Moreover, the presentation will inform about a recently started collaborative project (EU FP7 project No 603587) coordinated by SMHI and called SWITCH-ON http://water-switch-on.eu/. The project addresses water concerns and currently untapped potential of open data for improved water management across the EU. The overall goal of the project is to make use of open data, and add value to society by repurposing and refining data from various sources. SWITCH-ON will establish new forms of water research and facilitate the development of new products and services based on principles of sharing and community building in the water society. The SWITCH-ON objectives are to use open data for implementing: 1) an innovative spatial information platform with open data tailored for direct water assessments, 2) an entirely new form of collaborative research for water-related sciences, 3) fourteen new operational products and services dedicated to appointed end-users, 4) new business and knowledge to inform individual and collective decisions in line with the Europe's smart growth and environmental objectives. The presentation will discuss challenges, progress and opportunities with the open data strategy, based on the experiences from working both at a Governmental institute and being part of the global research community.

  12. [Mexican migration policies after IRCA].

    PubMed

    Alba, F

    1999-01-01

    The evolution since 1964 of Mexican government policy regarding migrant workers in the US is discussed. For a decade after the "bracero" program was terminated by the US, the Mexican government attempted to encourage creation of another legal framework for migration, regarded as inevitable whether legal or clandestine. Around 1974-75, a more distant attitude, termed the "policy of no policy," acquired considerable support in Mexican government and academic circles. The no-policy strategy allowed Mexico to achieve certain objectives regarding migration without prompting US intervention in its internal affairs, as for example by a linkage of US migration policy to specific Mexican government actions. The 1986 passage of the US Immigration Reform and Control Act effectively ended the no-policy strategy that had allowed the Mexican government to count on the continued emigration of Mexican workers without compromising its position of promoting respect for migrant rights. The unilateral change in the status quo by the US led to substitution of the "policy of dialogue," a clear signal of the Mexican government's search for a new migration agreement. The policy of dialogue has entailed greater discussion of the two traditional Mexican objectives regarding migration. Some progress has apparently been made concerning migrant rights, but the second and less explicit objective, that of preventing abrupt changes in US immigration policy and in migratory flows, is harder to judge. The atmosphere of freer public debate in Mexico is politicizing migratory policy.

  13. Flat-plate solar array project of the US Department of Energy's National Photovoltaics Program: Ten years of progress

    NASA Technical Reports Server (NTRS)

    Christensen, Elmer

    1985-01-01

    The Flat-Plate Solar Array (FSA) Project, a Government-sponsored photovoltaics project, was initiated in January 1975 (previously named the Low-Cost Silicon Solar Array Project) to stimulate the development of PV systems for widespread use. Its goal then was to develop PV modules with 10% efficiency, a 20-year lifetime, and a selling price of $0.50 per peak watt of generating capacity (1975 dollars). It was recognized that cost reduction of PV solar-cell and module manufacturing was the key achievement needed if PV power systems were to be economically competitive for large-scale terrestrial use.

  14. Prophets of Progress: Authority in the Scientific Projections and Religious Realizations of the Great Eastern Steamship.

    PubMed

    Gillin, Edward

    2015-10-01

    Naval architect John Scott Russell heralded the Great Eastern steamship as a beacon of modern science and used it to promote his own approaches to shipbuilding among Britain's science elites. While Russell defined the project through a rhetoric of science, to popular audiences the ship was analogous to biblical teachings, embodying profound moral lessons. This article places Russell's projections within this wider cultural context of religious interpretation and argues that in Victorian Britain the right to define the meaning of engineering spectacles was not the exclusive privilege of men of science, but open to broader cultural understandings. Religious, as much as scientific, values shaped social constructions of the project.

  15. [Implementing population-based integrated care for a region: a work-in-progress report on the project "Gesundes Kinzigtal"].

    PubMed

    Hildebrandt, Helmut; Schmitt, Gwendolyn; Roth, Monika; Stunder, Brigitte

    2011-01-01

    The regional integrated care model "Gesundes Kinzigtal" pursues the idea of integrated health care with special focus on increasing the health gain of the served population. Physicians (general practitioners) and psychotherapists, physiotherapists, hospitals, nursing services, non-profit associations, fitness centers, and health insurance companies work closely together with a regional management company and its programs on prevention and care coordination and enhancement. The 10 year-project is run by a company that was founded by the physician network "MQNK" and "OptiMedis AG", a corporation with public health background specialising in integrated health care. The aim of this project is to enhance prevention and quality of health care for a whole region in a sustainable way, and to decrease costs of care. The article describes the special funding model of the project, the engagement of patients, and the different health and prevention programmes. The programmes and projects are developed, implemented, and evaluated by multidisciplinary teams.

  16. The human genome project: Information management, access, and regulation. Technical progress report, 1 April--31 August 1993

    SciTech Connect

    McInerney, J.D.; Micikas, L.B.

    1993-09-10

    Efforts are described to prepare educational materials including computer based as well as conventional type teaching materials for training interested high school and elementary students in aspects of Human Genome Project.

  17. Resource Conservation and Recovery Act ground-water monitoring projects for Hanford Facilities: Progress report for the period July 1 to September 30, 1989 - Volume 1 - Text

    SciTech Connect

    Smith, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-12-01

    This is Volume 1 of a two-volume document that describes the progress of 14 Hanford Site ground-water monitoring projects for the period July 1 to September 30, 1989. This volume discusses the projects; Volume 2 provides as-built diagrams, completion/inspection reports, drilling logs, and geophysical logs for wells drilled, completed, or logged during this period. Volume 2 can be found on microfiche in the back pocket of Volume 1. The work described in this document is conducted by the Pacific Northwest Laboratory under the management of Westinghouse Hanford Company for the US Department of Energy. Concentrations of ground-water constituents are compared to federal drinking water standards throughout this document for reference purposes. All drinking water supplied from the sampled aquifer meets regulatory standards for drinking water quality.

  18. Resource Conservation and Recovery Act ground-water monitoring projects for Hanford facilities: Progress Report for the Period April 1 to June 30, 1989

    SciTech Connect

    Smith, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-09-01

    This report describes the progress of 13 Hanford ground-water monitoring projects for the period April 1 to June 30, 1989. These projects are for the 300 area process trenches (300 area), 183-H solar evaporation basins (100-H area), 200 areas low-level burial grounds, nonradioactive dangerous waste landfill (southeast of the 200 areas), 1301-N liquid waste disposal facility (100-N area), 1324-N surface impoundment and 1324-NA percolation pond (100-N area), 1325-N liquid waste disposal facility (100-N area), 216-A-10 crib (200-east area), 216-A-29 ditch (200-east area), 216-A-36B crib (200-east area), 216-B-36B crib (200-east area), 216-B-3 pond (east of the 200-east area), 2101-M pond (200-east area), grout treatment facility (200-east area).

  19. Microdroplet chain array for cell migration assays.

    PubMed

    Ma, Yan; Pan, Jian-Zhang; Zhao, Shi-Ping; Lou, Qi; Zhu, Ying; Fang, Qun

    2016-11-29

    Establishing cell migration assays in multiple different microenvironments is important in the study of tissue repair and regeneration, cancer progression, atherosclerosis, and arthritis. In this work, we developed a miniaturized and massive parallel microfluidic platform for multiple cell migration assays combining the traditional membrane-based cell migration technique and the droplet-based microfluidic technique. Nanoliter-scale droplets are flexibly assembled as building blocks based on a porous membrane to form microdroplet chains with diverse configurations for different assay modes. Multiple operations including in-droplet 2D/3D cell culture, cell co-culture and cell migration induced by a chemoattractant concentration gradient in droplet chains could be flexibly performed with reagent consumption in the nanoliter range for each assay and an assay scale-up to 81 assays in parallel in one microchip. We have applied the present platform to multiple modes of cell migration assays including the accurate cell migration assay, competitive cell migration assay, biomimetic chemotaxis assay, and multifactor cell migration assay based on the organ-on-a-chip concept, for demonstrating its versatility, applicability, and potential in cell migration-related research.

  20. Contracts for field projects and supporting research on enhanced oil recovery. Progress review quarter ending September 30, 1993

    SciTech Connect

    Not Available

    1994-08-01

    Progress reports are presented for the following tasks: chemical flooding--supporting research; gas displacement--supporting research; thermal recovery--supporting research; geoscience technology; resource assessment technology; and field demonstrations in high-priority reservoir classes. A list of available publications is also included.

  1. Annual Progress Report of the Coastal Bend Migrant Council Health Project, San Patricio Migrant Health Center (Texas), 1973-1974.

    ERIC Educational Resources Information Center

    Coastal Bend Migrant Council, Mathis, TX. San Patricio Migrant Health Center.

    The annual medical progress report covers migrant health services in San Patricio County, Texas, from February 1, 1973 to January 31, 1974. The report discusses: staff, administration, cardiology, dental services, health services, medical services, outreach and environmental health services, prescription services, registration and identification,…

  2. The Failure of Progressive Classroom Reform: Lessons from the Curriculum Reform Implementation Project in Papua New Guinea

    ERIC Educational Resources Information Center

    Guthrie, Gerard

    2012-01-01

    Progressive education has been an article of educational faith in Papua New Guinea during the last 50 years but the best available evidence indicates that major reforms to formalistic curriculum and teaching in primary and secondary classrooms have failed during this period despite large-scale professional, administrative and financial support. In…

  3. Contracts for field projects and supporting research on enhanced oil recovery. Progress review No. 71, quarter ending June 30, 1992

    SciTech Connect

    Not Available

    1993-06-01

    Progress reports are presented for the following tasks: chemical flooding--supporting research; gas displacement--supporting research; thermal recovery--supporting research; geoscience technology; resource assessment technology; microbial technology; and novel technology. A list of available publication is also provided.

  4. Progress in evaluation of radionuclide geochemical information developed by DOE high-level nuclear waste repository site projects: report for January-March 1985. Volume 2

    SciTech Connect

    Kelmers, A.D.; Seeley, F.G.; Arnold, W.D.; Blencoe, J.G.; Meyer, R.E.; Jacobs, G.K.; Whatley, S.K.

    1985-09-01

    Geochemical information relevant to the retention of radionuclides by the Hanford Site (in basalt) and the Yucca Mountain site (in tuff), candidate high-level nuclear waste geologic repositories being developed by US Department of Energy (DOE) projects, is being evaluated by Oak Ridge National Laboratory (ORNL) for the US Nuclear Regulatory Commission (NRC). Our evaluation of the sorption of technetium by basalt/groundwater systems was essentially completed this quarter and the results summarized; we conclude that the experimental methodology and results reported by the DOE for the Hanford Site have not conclusively established that significant retardation of technetium migration may be provided by phases present in the basalts of the Hanford Site. We have shown that sodium boltwoodite is the saturating uranium solid phase in two basalt/groundwater systems. Because thermodynamic data are not available for sodium boltwoodite, calculated solubilities for uranium are erroneous in these systems. Results of radionuclide solubility/speciation calculations, published by the DOE for the Yucca Mountain site, were evaluated this quarter under our geochemical modeling task. We express concerns relative to the inherent limitations of such calculations. Samples of Yucca Mountain tuff and J-13 well water were received for use in our planned radionuclide sorption/solubility experiments. These Yucca Mountain materials will be used to evaluate radionuclide sorption and apparent concentration limit values published by the Nevada Nuclear Waste Storage Investigations (NNWSI) project. 40 refs., 5 figs., 16 tabs.

  5. BX in-situ oil-shale project. Quarterly technical progress report, June 1, 1981-August 31, 1981

    SciTech Connect

    Dougan, P.M.

    1981-09-20

    June 1, 1981-August 31, 1981 was the third consecutive quarter of superheated steam injection at the BX In Situ Oil Shale Project. Injection was continuous except for the period of July 14th to August 1st when the injection was suspended during the drilling of core hole BX-37. During the quarter, 99,760 barrels of water as superheated steam were injected into Project injection wells at an average well head temperature of 752/sup 0/F and an average wellhead pressure of 1312 PSIG. During the same period, 135,469 barrels of fluid were produced from the Project production wells for a produced to injected fluid ratio of 1.36 to 1.0. Net oil production during the quarter was 38 barrels.

  6. Advanced fuel gas desulfurization (AFGD) demonstration project. Technical progress report No. 19, July 1, 1994--September 30, 1994

    SciTech Connect

    1995-12-01

    The {open_quotes}Advanced Flue Gas Desulfurization (AFGD) Demonstration Project{close_quotes} is a $150.5 million cooperative effort between the U.S. Department of Energy and Pure Air, a general partnership of Air Products and Chemicals, Inc. and Mitsubishi Heavy Industries America, Inc. The AFGD process is one of several alternatives to conventional flue gas desulfurization (FGD) being demonstrated under the Department of Energy`s Clean Coal Technology Demonstration Program. The AFGD demonstration project is located at the Northern Indiana Public Service Company`s Bailly Generating Station, about 12 miles northeast of Gary, Indiana.

  7. Microbial communities in subsurface environments: Diversity, origin, and evolution. Project technical progress report, September 1, 1993--August 31, 1996

    SciTech Connect

    Nierzwicki-Bauer, S.A.

    1994-05-02

    This report summarizes the progress made from 9-1-93 to 5-1-94 on this DOE grant. As participants in the subsurface science program, the authors are assessing the influence of environmental conditions on the distribution and evolution of subsurface microorganisms employing molecular techniques. The approach utilizes 16S rRNA targeted oligonucleotide probes, polymerase chain reaction (PCR) amplification of gene sequences, and sequencing techniques. Continued progress towards identifying target sequences for selected microbial types and groups is being made by analysis of rRNA sequence data for subsurface microorganisms and other microorganisms in the rRNA databases. Hybridization probes for these target sequences are being produced and used to classify isolated strains of subsurface microbes into focus clades useful for testing origins hypotheses.

  8. Nuclide-migration field experiments

    SciTech Connect

    Erdal, B.R.; Wolfsberg, K.; Johnstone, J.K.; Erickson, K.L.; Friedman, A.M.; Fried, S.; Hines, J.J.

    1981-03-01

    When considering groundwater flow and radionuclide retention in the complex flow systems that can occur in geologic formations, one has a serious problem in determining if laboratory studies are being performed under conditions appropriate to natural systems. This document is the project plan for a program designed to begin to address these problems. The project is being carried out jointly by the Los Alamos National Laboratory, Sandia National Laboratories, and Argonne National Laboratory. The work has three principal objectives: (1) to develop the experimental, instrumental, and safety techniques necessary to conduct controlled, small-scale radionuclide migration field experiments, including those involving actinides; (2) to use these techniques to define radionuclide migration through rock by performing generic, at-depth experiments under closely monitored conditions; and (3) to determine whether available lithologic, geochemical, and hydrologic properties together with existing or developing transport models are sufficient and appropriate to describe real field conditions.

  9. Medical migration. A study projects Americans spending up to $68 billion abroad by 2010 for treatment, but some doubt the trend's momentum.

    PubMed

    Rhea, Shawn

    2008-05-05

    As soaring costs are sending Americans abroad for healthcare, a new study projects they'll spend $68 billion annually by 2010 for overseas treatment. Besides that cost, it could pressure U.S. providers to deliver quality for less. "As you see other cultures where the outcomes look very favorable, then we'll see more people questioning why we can't provide that level of care at similar costs," says Jeffrey Moe, left.

  10. Migration and AIDS.

    PubMed

    Decosas, J; Kane, F; Anarfi, J K; Sodji, K D; Wagner, H U

    1995-09-23

    A successful short-term solution to transmission of AIDS in Western Africa by migrants involves provision of accessible and acceptable basic health and social services to migrants at their destination. The aim is to establish a sense of security and community, which is a health requirement. When migrants are excluded from community life or victimized as carriers of HIV infections, they will be driven by basic survival needs and dysfunctional social organization, which results in the rapid spread of HIV. Closing borders and mass deportation may not be an option. The long-term solution is population policy, environmental protection, and economic development. The focus on mapping the spread of AIDS must shift to a consideration of the migrant social conditions that make them vulnerable to AIDS. The issue of migration and AIDS will be addressed at the First European Conference on Tropical Medicine in October 1995 in Hamburg, Germany. In Uganda, HIV seroprevalence rates ranged from 5.5% among the stable population to 12.4% among internal migrants moving between villages to 16.3% among migrants from other areas. A World Bank project is operating in Western Africa, which traces seasonal male migration from the Cameroon to Liberia, Senegal to Nigeria, and from the Sahel to the coast during dry seasons. National border rules may influence the routes but not the extent of migration. A major destination place is Cote d' Ivoire, which has 25% of total population comprised of migrants from other countries and one of the highest HIV prevalence rates in Western Africa. On plantations prostitutes are brought in. Each prostitute serves about 25 workers. The pattern of sexual mixing contributes to the high HIV rates. Female migration is smaller and usually concentrated in prostitution at place of destination. Illiteracy and poverty drive women migrants into the trade. Their frequent health problems are malaria, pelvic pain, menstrual irregularity, vaginal discharge, and genital

  11. Hood River and Pelton Ladder Monitoring and Evaluation Project and Hood River Fish Habitat Project : Annual Progress Report 1999-2000.

    SciTech Connect

    Lambert, Michael B.; McCanna, Joseph P.; Jennings, Mick

    2001-02-01

    The Hood River subbasin is home to four species of anadromous salmonids: chinook salmon (Oncorhynchus tshawytscha), coho salmon (Oncorhynchus kisutch), steelhead (Oncorhynchus mykiss), and sea run cutthroat trout (Salmo clarki). Indigenous spring chinook salmon were extirpated during the late 1960's. The naturally spawning spring chinook salmon currently present in the subbasin are progeny of Deschutes stock. Historically, the Hood River subbasin hatchery steelhead program utilized out-of-basin stocks for many years. Indigenous stocks of summer and winter steelhead were listed in March 1998 by National Marine Fisheries Service (NMFS) under the Endangered Species Act (ESA) as a ''Threatened'' Species along with similar genetically similar steelhead in the Lower Columbia Basin. This annual report summarizes work for two consecutive contract periods: the fiscal year (FY) 1999 contract period was 1 October, 1998 through 30 September, 1999 and 1 October, 1999 through 30 September, 2000 for FY 2000. Work implemented during FY 1999 and FY 2000 included (1) acclimation of hatchery spring chinook salmon and hatchery summer and winter steelhead smolts, (2) spring chinook salmon spawning ground surveys on the West Fork Hood River (3) genetic analysis of steelhead and cutthroat [contractual service with the ODFW], (4) Hood River water temperature studies, (5) Oak Springs Hatchery (OSH) and Round Butte Hatchery (RBH) coded-wire tagging and clipping evaluation, (6) preparation of the Hood River Watershed Assessment (Coccoli et al., December 1999) and the Fish Habitat Protection, Restoration, and Monitoring Plan (Coccoli et al., February 2000), (7) project implementation of early action habitat protection and restoration projects, (8) Pelton Ladder evaluation studies, (9) management oversight and guidance to BPA and ODFW engineering on HRPP facilities, and (10) preparation of an annual report summarizing project objectives for FY 1999 and FY 2000.

  12. Displacement of diesel fuel with wind energy in rural Alaskan villages. Final progress and project closeout report

    SciTech Connect

    Meiners, Dennis; Drouhilet, Steve; Reeve, Brad; Bergen, Matt

    2002-03-11

    The basic concept behind this project was to construct a wind diesel hybrid power system which combines and maximizes the intermittent and variable energy output of wind turbine(s) with diesel generator(s) to provide continuous high quality electric power to weak isolated mini-grids.

  13. MDTA VOCATIONAL EXPERIMENTAL-DEMONSTRATION PROJECT FOR TRAINING AND PLACEMENT OF YOUTHFUL OFFENDERS. 15TH PROGRESS REPORT.

    ERIC Educational Resources Information Center

    MCKEE, JOHN M.; AND OTHERS

    IN THE DRAPER MANPOWER DEVELOPMENT AND TRAINING PROJECT, INITIATED TO TRAIN INSTITUTIONALIZED OFFENDERS IN TRADES, 810 INMATES HAVE BEEN TESTED FOR ABILITY, APTITUDE, AND EDUCATIONAL ACHIEVEMENT. A PICTURE VOCATIONAL PREFERENCE TEST WAS DEVISED TO OVERCOME THE GROUP'S VERBAL DISABILITY. OF THE 331 INMATES ACCEPTED FOR TRAINING, 231 HAVE GRADUATED,…

  14. MDTA VOCATIONAL EXPERIMENTAL-DEMONSTRATION PROJECT FOR TRAINING AND PLACEMENT OF YOUTHFUL OFFENDERS. 11TH PROGRESS REPORT, COMMUNITY SPONSORSHIP PROGRAM.

    ERIC Educational Resources Information Center

    MCKEE, JOHN M.; AND OTHERS

    THE VOCATIONAL EXPERIMENTAL-DEMONSTRATION PROJECT AT DRAPER CORRECTIONAL CENTER, AN EXPERIMENT TO REDUCE RECIDIVISM THROUGH VOCATIONAL TRAINING, IN ITS FIRST 21 MONTHS TRAINED 173 YOUTHS IN SEVEN TRADES AND PLACED 150 GRADUATES IN JOBS. DETAILS OF SELECTION, COUNSELING, TRAINING, PLACEMENT, AND FOLLOW-UP OF INMATES THE USE OF INDIVIDUALIZED…

  15. MDTA VOCATIONAL EXPERIMENTAL-DEMONSTRATION PROJECT FOR TRAINING AND PLACEMENT OF YOUTHFUL OFFENDERS. 14TH PROGRESS REPORT.

    ERIC Educational Resources Information Center

    MCKEE, JOHN M.; AND OTHERS

    DISSEMINATION OF PROGRAM FINDINGS TO THE CORRECTIONAL FIELD IS A KEY OBJECTIVE OF THE CURRENT PHASE OF THE EXPERIMENTAL-DEMONSTRATION PROJECT FOR VOCATIONAL TRAINING OF INMATES AT DRAPER CORRECTIONAL CENTER. LEADERS IN CORRECTIONS AND MANPOWER TRAINING WILL MEET IN FOUR CONFERENCES, PLANS FOR WHICH ARE OUTLINED IN THIS REPORT. BECAUSE 23 PERCENT…

  16. MDTA VOCATIONAL EXPERIMENTAL-DEMONSTRATION PROJECT FOR TRAINING AND PLACEMENT OF YOUTHFUL OFFENDERS. 13TH PROGRESS REPORT.

    ERIC Educational Resources Information Center

    MCKEE, JOHN M.; AND OTHERS

    INDIVIDUALLY DESIGNED BASIC EDUCATION PROGRAMS EMPHASIZING PROGRAMED INSTRUCTION TO PROVIDE MOTIVATION THROUGH CONTINUOUS FEEDBACK COMPLEMENT THE VOCATIONAL TRAINING GIVEN EACH INMATE PARTICIPATING IN THE DEMONSTRATION PROJECT AT THE DRAPER CORRECTIONAL CENTER. A REMEDIAL READING PROGRAM FOR ALL TRAINEES SCORING BELOW 7TH GRADE INCLUDES PHONICS…

  17. Working Group 7.0 Environmental Transport and Health Effects, Chernobyl Studies Project. Progress report, October 1994 -- March 1995

    SciTech Connect

    Anspaugh, L.R.; Hendrickson, S.M.

    1995-06-01

    This document presents the details from the working group 7.0 Chernobyl Studies Project. This working group looked at the environmental transport and health effects from the fallout due to the meltdown of Chernobylsk-4 reactor. Topics include: hydrological transport; chromosome painting dosimetry; EPR, TL and OSL dosimetry; stochastic effects; thyroid studies; and leukemia studies.

  18. Bilingual Mini-School Tutoring Project. Evaluation Progress Report Number 4, Final Evaluation, Program Year 2, July 1975.

    ERIC Educational Resources Information Center

    McConnell, Beverly

    The Bilingual Mini-School Tutoring Project offers parents a major role in their children's education as decision makers responsible for hiring and other areas of program operations and as teachers providing bilingual, bicultural instruction. The program design has two components: the mobile and the non-mobile component. The non-mobile program has…

  19. Bilingual Mini-School Tutoring Project. Evaluation Progress Report Number 2, Final Evaluation Program Year 1, July 1974.

    ERIC Educational Resources Information Center

    McConnell, Beverly

    An early childhood education program for children of migrant and seasonal farm workers, the Project provides tutoring, usually outside of regular school hours, to kindergarten and first grade children. The tutoring is done by adult paraprofessionals who are former migrants or seasonal farm workers. Program focus is to: (1) develop the child's…

  20. Smolt Migration Characteristics and Mainstem Snake and Columbia River Detection Rates of PIT-Tagged Grande Ronde and Imnaha River Naturally-Produced Spring Chinook Salmon, 1996 Annual Report : Fish Research Project, Oregon.

    SciTech Connect

    Sankovich, Paul; Keefe, MaryLouise; Carmichael, Richard W.

    1997-01-01

    This is the fifth year of a multi-year study to assess smolt migration characteristics and cumulative detection rates of naturally-produced chinook salmon (Oncorhynchus tshawytscha), from northeast Oregon streams. The goal of this project is to develop an understanding of interpopulation and interannual variation in several early life history characteristics of naturally-produced chinook salmon from the Grande Ronde and Imnaha River subbasins. This project provides information useful in the recovery of listed Snake River spring/summer chinook salmon. Specific populations included in the study are (1) Catherine Creek, (2) upper Grande Ronde River, (3) Lostine River, (4) Imnaha River, (5) Wenaha River, and (6) Minam River. In this document, we present findings from research completed in 1996. Naturally-produced chinook salmon populations in the Grande Ronde and Imnaha River subbasins have declined drastically in recent years due in part to habitat alterations and hydropower development. Declines have continued despite extensive mitigation efforts, including fish passage improvements, artificial production, supplementation, and habitat modification (BPA Division of Fish and Wildlife 1990). Snake River spring/summer chinook salmon (hereafter referred to as chinook salmon), which include naturally-produced chinook salmon in the Grande Ronde and Imnaha River subbasins, have been listed under the Endangered Species Act of 1973 as threatened or endangered since 1992.

  1. Implementation and assessment of a yeast orphan gene research project: involving undergraduates in authentic research experiences and progressing our understanding of uncharacterized open reading frames.

    PubMed

    Bowling, Bethany V; Schultheis, Patrick J; Strome, Erin D

    2016-02-01

    Saccharomyces cerevisiae was the first eukaryotic organism to be sequenced; however, little progress has been made in recent years in furthering our understanding of all open reading frames (ORFs). From October 2012 to May 2015 the number of verified ORFs had only risen from 75.31% to 78%, while the number of uncharacterized ORFs had decreased from 12.8% to 11% (representing > 700 genes still left in this category; http://www.yeastgenome.org/genomesnapshot). Course-based research has been shown to increase student learning while providing experience with real scientific investigation; however, implementation in large, multi-section courses presents many challenges. This study sought to test the feasibility and effectiveness of incorporating authentic research into a core genetics course, with multiple instructors, to increase student learning and progress our understanding of uncharacterized ORFs. We generated a module-based annotation toolkit and utilized easily accessible bioinformatics tools to predict gene function for uncharacterized ORFs within the Saccharomyces Genome Database (SGD). Students were each assigned an uncharacterized ORF, which they annotated using contemporary comparative genomics methodologies, including multiple sequence alignment, conserved domain identification, signal peptide prediction and cellular localization algorithms. Student learning outcomes were measured by quizzes, project reports and presentations, as well as a post-project questionnaire. Our results indicate that the authentic research experience had positive impacts on students' perception of their learning and their confidence to conduct future research. Furthermore, we believe that creation of an online repository and adoption and/or adaptation of this project across multiple researchers and institutions could speed the process of gene function prediction.

  2. Implementation and assessment of a yeast orphan gene research project; involving undergraduates in authentic research experiences and progressing our understanding of uncharacterized open reading frames

    PubMed Central

    Bowling, Bethany V.; Schultheis, Patrick J.

    2015-01-01

    Saccharomyces cerevisiae was the first eukaryotic organism to be sequenced, however little progress has been made in recent years in furthering our understanding of all open reading frames (ORFs). From October 2012 to May 2015 the number of verified ORFs has only risen from 75.31% to 78% while the number of uncharacterized ORFs have decreased from 12.8% to 11% (representing more than 700 genes still left in this category) [http://www.yeastgenome.org/genomesnapshot]. Course-based research has been shown to increase student learning while providing experience with real scientific investigation; however, implementation in large, multi-section courses presents many challenges. This study sought to test the feasibility and effectiveness of incorporating authentic research into a core genetics course with multiple instructors to increase student learning and progress our understanding of uncharacterized ORFs. We generated a module-based annotation toolkit and utilized easily accessible bioinformatics tools to predict gene function for uncharacterized ORFs within the Saccharomyces Genome Database (SGD). Students were each assigned an uncharacterized ORF which they annotated using contemporary comparative genomics methodologies including multiple sequence alignment, conserved domain identification, signal peptide prediction and cellular localization algorithms. Student learning outcomes were measured by quizzes, project reports and presentations, as well as a post-project questionnaire. Our results indicate the authentic research experience had positive impacts on student's perception of their learning and their confidence to conduct future research. Furthermore we believe that creation of an online repository and adoption and/or adaptation of this project across multiple researchers and institutions could speed the process of gene function prediction. PMID:26460164

  3. Advanced Flue Gas Desulfurization (AFGD) Demonstration Project. Technical progress report No. 15, July 1, 1993--September 30, 1993

    SciTech Connect

    Not Available

    1994-08-01

    The goal of this project is to demonstrate that, by combining state-of-the-art technology, highly efficient plant operation and maintenance capabilities and by-product gypsum sales, significant reductions of SO{sub 2} emissions can be achieved at approximately one-half the life cycle cost of a conventional Flue Gas Desulfurization (FGD) system. Further, this emission reduction is achieved without generating solid waste and while minimizing liquid wastewater effluent. Basically, this project entails the design, construction and operation of a nominal 600 MWe AFGD facility to remove SO{sub 2} from coal-fired power plant flue gas at the Northern Indiana Public Service Company`s Bailly Generating Station.

  4. Green River Formation Water Flood Demonstration Project, Uinta Basin, Utah. Quarterly technical progress report, July 1, 1993--September 30, 1993

    SciTech Connect

    Lomax, J.D.; Nielson, D.L.; Deo, M.D.

    1993-12-01

    The project is designed to increase recoverable petroleum reserves in the United States. The Green River Formation in Utah`s Uinta Basin contains abundant hydrocarbons that are not easily recovered by primary means. The successful Lomax Montument Butte Unit water flood will be evaluated under this contract, and based on this information, water floods will be initiated in nearby Travis and Boundary units. In 1987, Lomax Exploration Company started a water flood in the Monument Butte Unit of a Douglas Creek member of the Green River Formation. This was a low-enerey, geologically heterogeneous reservoir producing a waxy crude oil. Primary production yielded 5% of the OOIP. Due to the water flood project, total production will yield an estimated recovery of 20% OOIP.

  5. Investigating the San Andreas Fault System in the Northern Salton Trough by a Combination of Seismic Tomography and Pre-stack Depth Migration: Results from the Salton Seismic Imaging Project (SSIP)

    NASA Astrophysics Data System (ADS)

    Bauer, K.; Ryberg, T.; Fuis, G. S.; Goldman, M.; Catchings, R.; Rymer, M. J.; Hole, J. A.; Stock, J. M.

    2013-12-01

    The Salton Trough in southern California is a tectonically active pull-apart basin which was formed in migrating step-overs between strike-slip faults, of which the San Andreas fault (SAF) and the Imperial fault are current examples. It is located within the large-scale transition between the onshore SAF strike-slip system to the north and the marine rift system of the Gulf of California to the south. Crustal stretching and sinking formed the distinct topographic features and sedimentary successions of the Salton Trough. The active SAF and related fault systems can produce potentially large damaging earthquakes. The Salton Seismic Imaging Project (SSIP), funded by NSF and USGS, was undertaken to generate seismic data and images to improve the knowledge of fault geometry and seismic velocities within the sedimentary basins and underlying crystalline crust around the SAF in this key region. The results from these studies are required as input for modeling of earthquake scenarios and prediction of strong ground motion in the surrounding populated areas and cities. We present seismic data analysis and results from tomography and pre-stack depth migration for a number of seismic profiles (Lines 1, 4-7) covering mainly the northern Salton Trough. The controlled-source seismic data were acquired in 2011. The seismic lines have lengths ranging from 37 to 72 km. On each profile, 9-17 explosion sources with charges of 110-460 kg were recorded by 100-m spaced vertical component receivers. On Line 7, additional OBS data were acquired within the Salton Sea. Travel times of first arrivals were picked and inverted for initial 1D velocity models. Alternatively, the starting models were derived from the crustal-scale velocity models developed by the Southern California Earthquake Center. The final 2D velocity models were obtained using the algorithm of Hole (1992; JGR). We have also tested the tomography packages FAST and SIMUL2000, resulting in similar velocity structures. An

  6. Ground-water monitoring compliance projects for Hanford Site facilities: Progress report for the period January 1--March 31, 1988: Volume 1, Text

    SciTech Connect

    Not Available

    1988-05-01

    This report describes the progress of eight Hanford Site ground-water monitoring projects for the period January 1 to March 31, 1988. The facilities represented by the eight projects are the 300 Area Process trenches, 183-H Solar Evaporation Basins, 200 Areas Low-Level Burial Grounds, Nonradioactive Dangerous Waste Landfill, 216-A-36B Crib, 1301-N Liquid Waste Disposal Facility, 1325-N Liquid Waste Disposal Facility, and 1324-N/NA Surface Impoundment and Percolation Ponds. The latter four projects are included in this series of quarterly reports for the first time. This report is the seventh in a series of periodic status reports; the first six cover the period from May 1, 1986, through December 31, 1987 (PNL 1986; 1987a, b, c, d; 1988a). This report satisfies the requirements of Section 17B(3) of the Consent Agreement and Compliance Order issued by the Washington State Department of Ecology (1986a) to the US Department of Energy-Richland Operations Office. 13 refs., 19 figs., 24 tabs.

  7. RCRA (Resource Conservation and Recovery Act of 1976) ground-water monitoring projects for Hanford facilities: Progress report, October 1--December 31, 1988: Volume 1, Text

    SciTech Connect

    Fruland, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-04-01

    This report describes the progress of 13 Hanford ground-water monitoring projects for the period October 1 to December 31, 1988. There are 16 individual hazardous waste facilities covered by the 13 ground-water monitoring projects. The Grout Treatment Facility is included in this series of quarterly reports for the first time. The 13 projects discussed in this report were designed according to applicable interim-status ground-water monitoring requirements specified in the Resource Conservation and Recovery Act of 1976 (RCRA). During this quarter, field activities primarily consisted of sampling and analyses, and water-level monitoring. The 200 Areas Low-Level Burial Grounds section includes sediment analyses in addition to ground-water monitoring results. Twelve new wells were installed during the previous quarter: two at the 216-A-29 Ditch, six at the 216-A-10 Crib, and four at the 216-B-3 Pond. Preliminary characterization data for these new wells include drillers' logs and other drilling and site characterization data, and are provided in Volume 2 or on microfiche in the back of Volume 1. 26 refs., 28 figs., 74 tabs.

  8. Estimations of the extent of migration of surficially applied water for various surface conditions near the potential repository perimeter; Yucca Mountain Site Characterization Project

    SciTech Connect

    Sobolik, S.R.; Fewell, M.E.

    1993-12-01

    The Yucca Mountain Site Characterization Project is studying Yucca Mountain in southwestern Nevada as a potential site for a high-level nuclear waste repository. Site characterization includes surface-based and underground testing. Analyses have been performed to support the design of site characterization activities so to have minimal impact on the ability of the site to isolate waste, and on tests performed as part of the characterization process. Two examples of site characterization activities are the construction of an Exploratory Studies Facility, which may include underground shafts, drifts, and ramps, and surface-based testing activities, which may require borehole drilling, excavation of test pits, and road watering for dust control. The information in this report pertains to two-dimensional numerical calculations modeling the movement of surficially applied water and the potential effects of that water on repository performance and underground experiments. This document contains information that has been used in preparing recommendations for two Yucca Mountain Site Characterization Project documents: Appendix I of the Exploratory Studies Facility Design Requirements document, and the Surface-Based Testing Field Requirements Document.

  9. Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification.

    PubMed

    Omenn, Gilbert S; Lane, Lydie; Lundberg, Emma K; Beavis, Ronald C; Nesvizhskii, Alexey I; Deutsch, Eric W

    2015-09-04

    Remarkable progress continues on the annotation of the proteins identified in the Human Proteome and on finding credible proteomic evidence for the expression of "missing proteins". Missing proteins are those with no previous protein-level evidence or insufficient evidence to make a confident identification upon reanalysis in PeptideAtlas and curation in neXtProt. Enhanced with several major new data sets published in 2014, the human proteome presented as neXtProt, version 2014-09-19, has 16,491 unique confident proteins (PE level 1), up from 13,664 at 2012-12 and 15,646 at 2013-09. That leaves 2948 missing proteins from genes classified having protein existence level PE 2, 3, or 4, as well as 616 dubious proteins at PE 5. Here, we document the progress of the HPP and discuss the importance of assessing the quality of evidence, confirming automated findings and considering alternative protein matches for spectra and peptides. We provide guidelines for proteomics investigators to apply in reporting newly identified proteins.

  10. The PixFEL project: Progress towards a fine pitch X-ray imaging camera for next generation FEL facilities

    NASA Astrophysics Data System (ADS)

    Rizzo, G.; Batignani, G.; Benkechkache, M. A.; Bettarini, S.; Casarosa, G.; Comotti, D.; Dalla Betta, G.-F.; Fabris, L.; Forti, F.; Grassi, M.; Lodola, L.; Malcovati, P.; Manghisoni, M.; Mendicino, R.; Morsani, F.; Paladino, A.; Pancheri, L.; Paoloni, E.; Ratti, L.; Re, V.; Traversi, G.; Vacchi, C.; Verzellesi, G.; Xu, H.

    2016-07-01

    The INFN PixFEL project is developing the fundamental building blocks for a large area X-ray imaging camera to be deployed at next generation free electron laser (FEL) facilities with unprecedented intensity. Improvement in performance beyond the state of art in imaging instrumentation will be explored adopting advanced technologies like active edge sensors, a 65 nm node CMOS process and vertical integration. These are the key ingredients of the PixFEL project to realize a seamless large area focal plane instrument composed by a matrix of multilayer four-side buttable tiles. In order to minimize the dead area and reduce ambiguities in image reconstruction, a fine pitch active edge thick sensor is being optimized to cope with very high intensity photon flux, up to 104 photons per pixel, in the range from 1 to 10 keV. A low noise analog front-end channel with this wide dynamic range and a novel dynamic compression feature, together with a low power 10 bit analog to digital conversion up to 5 MHz, has been realized in a 110 μm pitch with a 65 nm CMOS process. Vertical interconnection of two CMOS tiers will be also explored in the future to build a four-side buttable readout chip with high density memories. In the long run the objective of the PixFEL project is to build a flexible X-ray imaging camera for operation both in burst mode, like at the European X-FEL, or in continuous mode with the high frame rates anticipated for future FEL facilities.

  11. Progress in evaluation of radionuclide geochemical information developed by DOE high-level nuclear waste repository site projects. Report for April-June 1985. Volume 3

    SciTech Connect

    Kelmers, A.D.; Arnold, W.D.; Blencoe, J.G.; Meyer, R.E.; Jacobs, G.K.; Whatley, S.K.

    1986-02-01

    Geochemical information relevant to the potential mobility of radionuclides at the Hanford Site and the Yucca Mountain site, candidate sites for high-level nuclear waste geologic repositories being developed by Department of Energy projects, is being evaluated by Oak Ridge National Laboratory (ORNL) for the US Nuclear Regulatory Commission. Neptunium(V) sorption isotherms in three different basalt/synthetic groundwater systems were initiated this quarter. Uranium(VI) sorption isotherms were completed with McCoy Canyon basalt and synthetic groundwater GR-2. The control of U(VI) solutions at a level of {similar_to}10{sup -4} mol/L is apparently dominated by the precipitation of sodium boltwoodite. Different apparent concentration limits for uranium were obtained with GR-2 and GR-4 solutions. The results suggest that uranium sorption/solubility behavior could be substantially different in the various basalt units likely to be encountered by groundwater during migration from the waste package to the accessible environment. The EQ3/6 software package was implemented and tested on the ORNL computer system. 13 refs., 2 figs., 1 tab.

  12. New concept for coal wettability evaluation and modulation. Technical progress report for the project, July 1, 1995--September 30, 1995

    SciTech Connect

    Hu, W.

    1995-12-31

    This project is concerned with the new concept for coal surface wettability and floatability evaluation and modulation. the objective of the work is the fundamental surface chemistry features about the evaluation of the surface wettability and floatability of coal and pyrite, and establish a new separation strategy which could contribute to advanced coal-cleaning for premium fuel application. In this quarter, the mini-cell flotation tests are conducted to study kinetic floatability and kinetic collectability of coal and pyrite. The kinetic floatability of the five samples have been tested with methanol, butanol, and hexanol as collector.

  13. General-purpose heat source project and space nuclear safety and fuels program. Progress reportt, January 1980

    SciTech Connect

    Maraman, W.J.

    1980-04-01

    This formal monthly report covers the studies related to the use of /sup 238/PuO/sub 2/ in radioisotopic power systems carried out for the Advanced Nuclear Systems and Projects Division of the Los Alamos Scientific Laboratory. The two programs involved are the general-purpose heat source development and space nuclear safety and fuels. Most of the studies discussed here are of a continuing nature. Results and conclusions described may change as the work continues. Published reference to the results cited in this report should not be made without the explicit permission of the person in charge of the work.

  14. Geothermal direct-heat utilization assistance. Federal Assistance Program, Quarterly project progress report, October--December 1994

    SciTech Connect

    Not Available

    1994-12-31

    The report summarizes activities of the Geo-Heat Center (GHC) at Oregon Institute of Technology for the first quarter of Fiscal Year 1995. It describes contacts with parties during this period related to assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, resources and equipment. Research is also being conducted on geothermal energy cost evaluation, low-temperature geothermal resource assessment, use of silica waste from the Cerro Prieto geothermal field as construction materials and geothermal heat pumps. Outreach activities include the publication of a quarterly Bulletin on direct heat applications and dissemination of information on low-temperature geothermal resources and utilization.

  15. Population, migration and urbanization.

    PubMed

    1982-06-01

    Despite recent estimates that natural increase is becoming a more important component of urban growth than rural urban transfer (excess of inmigrants over outmigrants), the share of migration in the total population growth has been consistently increasing in both developed and developing countries. From a demographic perspective, the migration process involves 3 elements: an area of origin which the mover leaves and where he or she is considered an outmigrant; the destination or place of inmigration; and the period over which migration is measured. The 2 basic types of migration are internal and international. Internal migration consists of rural to urban migration, urban to urban migration, rural to rural migration, and urban to rural migration. Among these 4 types of migration various patterns or processes are followed. Migration may be direct when the migrant moves directly from the village to the city and stays there permanently. It can be circular migration, meaning that the migrant moves to the city when it is not planting season and returns to the village when he is needed on the farm. In stage migration the migrant makes a series of moves, each to a city closer to the largest or fastest growing city. Temporary migration may be 1 time or cyclical. The most dominant pattern of internal migration is rural urban. The contribution of migration to urbanization is evident. For example, the rapid urbanization and increase in urban growth from 1960-70 in the Republic of Korea can be attributed to net migration. In Asia the largest component of the population movement consists of individuals and groups moving from 1 rural location to another. Recently, because urban centers could no longer absorb the growing number of migrants from other places, there has been increased interest in the urban to rural population redistribution. This reverse migration also has come about due to slower rates of employment growth in the urban centers and improved economic opportunities

  16. [Circular migration in Indonesia].

    PubMed

    Mantra, I B

    1979-12-01

    The author examines circular migration in Indonesia, with primary focus on the 1970s. It is found that circular, or repeated return migration, generally occurs over short distances and for short periods and is more frequent than lifetime migration. The relationships between improvements in the national transport system, access to labor force opportunities in both the formal and informal sectors of the economy, and circular migration are discussed.

  17. Progress and challenges in modelling country-level HIV/AIDS epidemics: the UNAIDS Estimation and Projection Package 2007.

    PubMed

    Brown, T; Salomon, J A; Alkema, L; Raftery, A E; Gouws, E

    2008-08-01

    The UNAIDS Estimation and Projection Package (EPP) was developed to aid in country-level estimation and short-term projection of HIV/AIDS epidemics. This paper describes advances reflected in the most recent update of this tool (EPP 2007), and identifies key issues that remain to be addressed in future versions. The major change to EPP 2007 is the addition of uncertainty estimation for generalised epidemics using the technique of Bayesian melding, but many additional changes have been made to improve the user interface and efficiency of the package. This paper describes the interface for uncertainty analysis, changes to the user interface for calibration procedures and other user interface changes to improve EPP's utility in different settings. While formal uncertainty assessment remains an unresolved challenge in low-level and concentrated epidemics, the Bayesian melding approach has been applied to provide analysts in these settings with a visual depiction of the range of models that may be consistent with their data. In fitting the model to countries with longer-running epidemics in sub-Saharan Africa, a number of limitations have been identified in the current model with respect to accommodating behaviour change and accurately replicating certain observed epidemic patterns. This paper discusses these issues along with their implications for future changes to EPP and to the underlying UNAIDS Reference Group model.

  18. Projects at the Western Environmental Technology Office. Quarterly technical progress report, July 1, 1995--September 30, 1995

    SciTech Connect

    1996-01-01

    The goal of this project is to demonstrate the technical and economic feasibility of commercializing a biotechnology that uses plants to remediate soils, sediments, surface waters, and groundwaters contaminated by heavy metals and radionuclides. This technology, known as phytoremediation, is particularly suited to remediation of soils or water where low levels of contaminants are widespread. Project objectives are to provide an accurate estimate of the capability and rate of phytoremediation for removal of contaminants of concern from soils and groundwaters at Department of Energy (DOE) sites and to develop data suitable for engineering design and economic feasibility evaluations, including methods for destruction or final disposition of plants containing contaminants of concern. The bioremediation systems being evaluated could be less expensive than soil removal and treatment systems, given the areal extent and topography of sites under consideration and the investment of energy and money in soil-moving and -treating processes. In situ technology may receive regulatory acceptance more easily than ex situ treatments requiring excavation, processing, and replacement of surface soils. In addition, phytoremediation may be viable for cleanup of contaminated waters, either as the primary treatment or the final polishing stage, depending on the contaminant concentrations and process economics considerations.

  19. Sour gas plant subsurface remediation technology research and demonstration project. Quarterly technical progress report, January 1, 1994--March 31, 1994

    SciTech Connect

    Stepan, D.J.; Kuehnel, V.

    1994-04-01

    Recognizing the potential impacts of sour gas plant operations on the subsurface environment, the Canadian Association of Petroleum Producers (CAPP), formerly the Canadian Petroleum Association (CPA), and Environment Canada initiated a multiphase study focusing on research related to the development and demonstration of remedial technologies for soil and groundwater contamination at these facilities. The first phase of the project was completed in 1990, and consisted of a comprehensive review of all soil and groundwater monitoring data submitted to Alberta Environment by sour gas plants in accordance with the Clean Water Act (1980). That review indicated that all but one of the 45 sour gas plants for which data were available exhibited some form of impact on soil and groundwater quality. The study identified the most frequently occurring contamination situations at the sites and classified them by source, type of contaminant, and the hydrogeological characteristics of the contaminated setting. The project steering committee subsequently selected the Strachan Gas Plant, located near Rocky Mountain House, Alberta, Canada, as a field research and remediation technology demonstration site. Research to be performed under this agreement is for activities in the areas of soil vapor extraction (SVE), bioventing, and bioremediation, all focusing on residual contamination in the unsaturated, or vadose, zone at the site, as well as evaluations of biological treatment of groundwater and ex situ soil remediation using solvent extraction in conjunction with photooxidation, solvent extraction in conjunction with microwave irradiation, and low-temperature thermal desorption.

  20. Migration within China and from China to the USA: the effects of migration networks, selectivity, and the rural political economy in Fujian Province.

    PubMed

    Liang, Zai; Chunyu, Miao David

    2013-07-01

    This paper tests a new strategy for simultaneously studying internal migration within, and international migration from, China. Our theoretical discussion draws on ideas from migration-networks theory and studies of the transition to a market-oriented economy. Data collection is modelled on the Mexican Migration Project. We find that education is more important in initiating internal migration than international migration. Second, although the role of migration networks at a community level seems similar to that for Mexico-USA migration, the networks at a family level show a different pattern. Third, there is evidence that internal and international migration are competing options. Finally, we find that individuals with cadres (public officials) in the family are less likely to undertake internal migration, but more likely to participate in international migration, a finding that highlights the continuing significance of the cadres in coastal rural China.

  1. Migration within China and from China to the USA: The effects of migration networks, selectivity, and the rural political economy in Fujian Province

    PubMed Central

    Liang, Zai; Chunyu, Miao David

    2013-01-01

    This paper tests a new strategy to study domestic and international migration from China simultaneously. Our theoretical discussion draws on ideas from migration networks theory and the market transition debate. Data collection is modeled on the Mexican Migration Project. We find that education is more important in the initiation of internal migration than international migration. Second, although there is consistent evidence regarding the role of migration networks at a community level, migration networks at a family level show a different pattern compared to that in Mexico-US migration. Third, there is evidence that internal and international migration “deters” each other. Finally, we find that individuals with cadres in the family are less likely to undertake internal migration but more likely to participate in international migration, a finding that highlights the continuing significance of positional power in coastal rural China. PMID:23368517

  2. More Myths of Migration.

    ERIC Educational Resources Information Center

    Basch, Linda; Lerner, Gail

    1986-01-01

    Challenges "myths" about women and migration, including (1) the causes of migration are economic, not racism; (2) migrant women receive support from feminist groups and trade unions; (3) transnational corporations are positive forces in developing nations; (4) migration today has little impact on family life; and (5) most migrants cluster in…

  3. Migration and Adult Education

    ERIC Educational Resources Information Center

    Gois, William

    2007-01-01

    The objective of this paper is to highlight the role of adult education as a tool in addressing labour migration issues, specifically those concerning the protection of migrant workers' rights and the transformation of the impact of migration into positive holistic developmental gains. The view of labour migration as a means to forge the economic…

  4. Study of Mechanisms of Aerosol Indirect Effects on Glaciated Clouds: Progress during the Project Final Technical Report

    SciTech Connect

    Phillips, Vaughan T. J.

    2013-10-18

    This 3-year project has studied how aerosol pollution influences glaciated clouds. The tool applied has been an 'aerosol-cloud model'. It is a type of Cloud-System Resolving Model (CSRM) modified to include 2-moment bulk microphysics and 7 aerosol species, as described by Phillips et al. (2009, 2013). The study has been done by, first, improving the model and then performing sensitivity studies with validated simulations of a couple of observed cases from ARM. These are namely the Tropical Warm Pool International Cloud Experiment (TWP-ICE) over the tropical west Pacific and the Cloud and Land Surface Interaction Campaign (CLASIC) over Oklahoma. During the project, sensitivity tests with the model showed that in continental clouds, extra liquid aerosols (soluble aerosol material) from pollution inhibited warm rain processes for precipitation production. This promoted homogeneous freezing of cloud droplets and aerosols. Mass and number concentrations of cloud-ice particles were boosted. The mean sizes of cloud-ice particles were reduced by the pollution. Hence, the lifetime of glaciated clouds, especially ice-only clouds, was augmented due to inhibition of sedimentation and ice-ice aggregation. Latent heat released from extra homogeneous freezing invigorated convective updrafts, and raised their maximum cloud-tops, when aerosol pollution was included. In the particular cases simulated in the project, the aerosol indirect effect of glaciated clouds was twice than of (warm) water clouds. This was because glaciated clouds are higher in the troposphere than water clouds and have the first interaction with incoming solar radiation. Ice-only clouds caused solar cooling by becoming more extensive as a result of aerosol pollution. This 'lifetime indirect effect' of ice-only clouds was due to higher numbers of homogeneously nucleated ice crystals causing a reduction in their mean size, slowing the ice-crystal process of snow production and slowing sedimentation. In addition

  5. Quality Indicators in Laboratory Medicine: the status of the progress of IFCC Working Group "Laboratory Errors and Patient Safety" project.

    PubMed

    Sciacovelli, Laura; Lippi, Giuseppe; Sumarac, Zorica; West, Jamie; Garcia Del Pino Castro, Isabel; Furtado Vieira, Keila; Ivanov, Agnes; Plebani, Mario

    2017-03-01

    The knowledge of error rates is essential in all clinical laboratories as it enables them to accurately identify their risk level, and compare it with those of other laboratories in order to evaluate their performance in relation to the State-of-the-Art (i.e. benchmarking) and define priorities for improvement actions. Although no activity is risk free, it is widely accepted that the risk of error is minimized by the use of Quality Indicators (QIs) managed as a part of laboratory improvement strategy and proven to be suitable monitoring and improvement tools. The purpose of QIs is to keep the error risk at a level that minimizes the likelihood of patients. However, identifying a suitable State-of-the-Art is challenging, because it calls for the knowledge of error rates measured in a variety of laboratories throughout world that differ in their organization and management, context, and the population they serve. Moreover, it also depends on the choice of the events to keep under control and the individual procedure for measurement. Although many laboratory professionals believe that the systemic use of QIs in Laboratory Medicine may be effective in decreasing errors occurring throughout the total testing process (TTP), to improve patient safety as well as to satisfy the requirements of International Standard ISO 15189, they find it difficult to maintain standardized and systematic data collection, and to promote continued high level of interest, commitment and dedication in the entire staff. Although many laboratories worldwide express a willingness to participate to the Model of QIs (MQI) project of IFCC Working Group "Laboratory Errors and Patient Safety", few systematically enter/record their own results and/or use a number of QIs designed to cover all phases of the TTP. Many laboratories justify their inadequate participation in data collection of QIs by claiming that the number of QIs included in the MQI is excessive. However, an analysis of results suggests

  6. Progress report on terrestrial model development (TERRA and HABITAT): Research in support of the CERES earth system modeling project

    SciTech Connect

    Kercher, J.R.; Axelrod, M.C.; Amthor, J.S.; Chambers, J.Q. |

    1994-05-01

    Although there is only a developing understanding of the many processes affecting and coupling the atmosphere, oceans, and land systems of the earth, we are embarked on an effort to construct a prototype model (CERES) of the full Earth system. As part of this effort, we have proposed to the EPA to construct an Earth System Framework for the CERES model that supports flexible, modular development, coupling, and replacement of Earth System submodel components. This project has two specific areas of study. These areas are (1) the terrestrial contribution to the biogeochemical cycling and (2) the interactions of climate and the land ecosystems. The objectives of these two areas of study are: development of a globally distributed model of terrestrial ecosystem productivity, linking model to the submodels, using coupled system to explore biogeochemical cycles, exploration of greenhouse effect, development of models of surface, and the study of the dynamics of climate change and vegetation response.

  7. [The theory of migration].

    PubMed

    Delbruck, C; Raffelhuschen, B

    1993-09-01

    "The present and expected migration flows in Europe require a detailed analysis of determinants and elements of migration decisions. This survey encompasses a view on classical--labor market and demand side oriented--theories, the more recent human capital approach as well as on migration under asymmetric information. Since these theories so far yield an unsatisfactory basis for description and forecasting of multilateral migration flows, a closer look at empirical methods of migration research is taken. Consequently, a description of possible policy oriented applications of the gravity model and the random utility approach, with their descriptive and normative characteristics, is given." (SUMMARY IN ENG)

  8. Molecular genetics of neuronal migration disorders.

    PubMed

    Liu, Judy S

    2011-04-01

    Cortical malformations associated with defects in neuronal migration result in severe developmental consequences including intractable epilepsy and intellectual disability. Genetic causes of migration defects have been identified with the advent and widespread use of high-resolution MRI and genetic techniques. Thus, the full phenotypic range of these genetic disorders is becoming apparent. Genes that cause lissencephaly, pachygyria, subcortical band heterotopia, and periventricular nodular heterotopias have been defined. Many of these genes are involved in cytoskeletal regulation including the function of microtubules (LIS1, TUBA1A,TUBB3, and DCX) and of actin (FilaminA). Thus, the molecular pathways regulating neuronal migration including the cytoskeletal pathways appear to be defined by human mutation syndromes. Basic science, including cell biology and animal models of these disorders, has informed our understanding of the pathogenesis of neuronal migration disorders and further progress depends on the continued integration of the clinical and basic sciences.

  9. Analyzing bat migration

    USGS Publications Warehouse

    Cryan, Paul M.; Diehl, Robert H.

    2009-01-01

    T HE MIGRATORY MOVEIvl.ENTS OF BATS have proven ex­ tremely difficult to determine. Despite extensive efforts during the past century to track the movements of bats across landscapes, efficient methods of following small- to medium-size volant animals <240 gl for extended periods (>8 weeks) over long distances (>100 km) have not been developed. Important questions about bat migration remain unanswered: Which bats migrate? Where do they go? How far do they move? How high and fast do they fly? What are their habitat needs during migration? How do bats orient and navigate during migration? Addressing these apparently simple questions will be a considerable challenge to anyone interested in advancing the study of bat migration. In this chapter, we present direct and indirect methods used to study bat migration as well as techniques that have worked for studying bird migration that could feasibly be adapted to the study of bats.

  10. Contracts for field projects and supporting research on enhanced oil recovery. Progress review No. 80. Quarterly report, July--September, 1994

    SciTech Connect

    1995-11-01

    This report contains information on petroleum enhanced recovery projects. In addition to project descriptions, contract numbers, principal investigators and project management information is included.

  11. Compilation and analyses of emissions inventories for NOAA`s atmospheric chemistry project. Progress report, August 1997

    SciTech Connect

    Benkovitz, C.M.; Mubaraki, M.A.

    1997-09-01

    Global inventories of anthropogenic emissions of oxides of nitrogen (NO{sub x}) for circa 1985 and 1990 and Non-Methane Volatile Organic Compounds (NMVOCs) for circa 1990 have been compiled by this project. Work on the inventories has been carried out under the umbrella of the Global Emissions Inventory Activity (GEIA) of the International Global Atmospheric Chemistry (IGAC) Program. The 1985 NO{sub x} inventory was compiled using default data sets of global emissions that were refined via the use of more detailed regional data sets; this inventory is being distributed to the scientific community at large as the GEIA Version 1A inventory. Global emissions of NO{sub x} for 1985 are estimated to be 21 Tg N y{sup -1}, with approximately 84% originating in the Northern Hemisphere. The 1990 inventories of NO{sub x} and NMVOCs were compiled using unified methodologies and data sets in collaboration with the Netherlands National Institute of Public Health and Environmental Protection (Rijksinstituut Voor Volksgezondheid en Milieuhygiene, RIVM) and the Division of Technology for Society of the Netherlands Organization for Applied Scientific Research, (IMW-TNO); these emissions will be used as the default estimates to be updated with more accurate regional data. The NMVOC inventory was gridded and speciated into 23 chemical categories.

  12. Gas generation and gas migration in deep geological repositories for radioactive waste

    SciTech Connect

    Haijtink, B.

    1996-12-31

    It is generally accepted that there will be some degree of gas generation in deep geological repositories for radioactive waste. This gas generation will depend on a number of factors such as the nature of the waste, the waste container, the buffer material and the near field host rock. In an ideal situation the gas generated would all dissolve in the groundwater and/or be transported away from the deep repository by the mechanisms of advection, diffusion and dispersion. However the sought-after characteristic of a repository host medium of very low permeability, e.g. bentonite buffer material and argillaceous geological media can be problematic when considering gas migration. High gas pressures might be build-up which could lead to potential fracturing of engineered barriers in the near field and enhancing groundwater flow and radionuclide migration. Various theoretical as well as experimental research activities have been undertaken to investigate the different phenomena. Within the framework of R&D programmes on Management and Storage of Radioactive Waste, conducted by the European Commission, some of the research activities are grouped together in a coordinated project named PEGASUS (Project on the Effects of GAS in an Underground Storage facility). In this project a total of about twenty research institutes and laboratories from seven different European countries are involved. This PEGASUS project will be followed up by a new project named PROGRESS (PROject of Research into Gas generation and migration in radioactive waste REpository SystemS). In this paper, an overview is given of the various research activities carried out and results obtained so far.

  13. Metrics for the Human Proteome Project 2016: Progress on Identifying and Characterizing the Human Proteome, Including Post-Translational Modifications.

    PubMed

    Omenn, Gilbert S; Lane, Lydie; Lundberg, Emma K; Beavis, Ronald C; Overall, Christopher M; Deutsch, Eric W

    2016-11-04

    The HUPO Human Proteome Project (HPP) has two overall goals: (1) stepwise completion of the protein parts list-the draft human proteome including confidently identifying and characterizing at least one protein product from each protein-coding gene, with increasing emphasis on sequence variants, post-translational modifications (PTMs), and splice isoforms of those proteins; and (2) making proteomics an integrated counterpart to genomics throughout the biomedical and life sciences community. PeptideAtlas and GPMDB reanalyze all major human mass spectrometry data sets available through ProteomeXchange with standardized protocols and stringent quality filters; neXtProt curates and integrates mass spectrometry and other findings to present the most up to date authorative compendium of the human proteome. The HPP Guidelines for Mass Spectrometry Data Interpretation version 2.1 were applied to manuscripts submitted for this 2016 C-HPP-led special issue [ www.thehpp.org/guidelines ]. The Human Proteome presented as neXtProt version 2016-02 has 16,518 confident protein identifications (Protein Existence [PE] Level 1), up from 13,664 at 2012-12, 15,646 at 2013-09, and 16,491 at 2014-10. There are 485 proteins that would have been PE1 under the Guidelines v1.0 from 2012 but now have insufficient evidence due to the agreed-upon more stringent Guidelines v2.0 to reduce false positives. neXtProt and PeptideAtlas now both require two non-nested, uniquely mapping (proteotypic) peptides of at least 9 aa in length. There are 2,949 missing proteins (PE2+3+4) as the baseline for submissions for this fourth annual C-HPP special issue of Journal of Proteome Research. PeptideAtlas has 14,629 canonical (plus 1187 uncertain and 1755 redundant) entries. GPMDB has 16,190 EC4 entries, and the Human Protein Atlas has 10,475 entries with supportive evidence. neXtProt, PeptideAtlas, and GPMDB are rich resources of information about post-translational modifications (PTMs), single amino acid

  14. Progress on Optimizing Miscanthus Biomass Production for the European Bioeconomy: Results of the EU FP7 Project OPTIMISC

    PubMed Central

    Lewandowski, Iris; Clifton-Brown, John; Trindade, Luisa M.; van der Linden, Gerard C.; Schwarz, Kai-Uwe; Müller-Sämann, Karl; Anisimov, Alexander; Chen, C.-L.; Dolstra, Oene; Donnison, Iain S.; Farrar, Kerrie; Fonteyne, Simon; Harding, Graham; Hastings, Astley; Huxley, Laurie M.; Iqbal, Yasir; Khokhlov, Nikolay; Kiesel, Andreas; Lootens, Peter; Meyer, Heike; Mos, Michal; Muylle, Hilde; Nunn, Chris; Özgüven, Mensure; Roldán-Ruiz, Isabel; Schüle, Heinrich; Tarakanov, Ivan; van der Weijde, Tim; Wagner, Moritz; Xi, Qingguo; Kalinina, Olena

    2016-01-01

    This paper describes the complete findings of the EU-funded research project OPTIMISC, which investigated methods to optimize the production and use of miscanthus biomass. Miscanthus bioenergy and bioproduct chains were investigated by trialing 15 diverse germplasm types in a range of climatic and soil environments across central Europe, Ukraine, Russia, and China. The abiotic stress tolerances of a wider panel of 100 germplasm types to drought, salinity, and low temperatures were measured in the laboratory and a field trial in Belgium. A small selection of germplasm types was evaluated for performance in grasslands on marginal sites in Germany and the UK. The growth traits underlying biomass yield and quality were measured to improve regional estimates of feedstock availability. Several potential high-value bioproducts were identified. The combined results provide recommendations to policymakers, growers and industry. The major technical advances in miscanthus production achieved by OPTIMISC include: (1) demonstration that novel hybrids can out-yield the standard commercially grown genotype Miscanthus x giganteus; (2) characterization of the interactions of physiological growth responses with environmental variation within and between sites; (3) quantification of biomass-quality-relevant traits; (4) abiotic stress tolerances of miscanthus genotypes; (5) selections suitable for production on marginal land; (6) field establishment methods for seeds using plugs; (7) evaluation of harvesting methods; and (8) quantification of energy used in densification (pellet) technologies with a range of hybrids with differences in stem wall properties. End-user needs were addressed by demonstrating the potential of optimizing miscanthus biomass composition for the production of ethanol and biogas as well as for combustion. The costs and life-cycle assessment of seven miscanthus-based value chains, including small- and large-scale heat and power, ethanol, biogas, and insulation

  15. Measuring research progress in photovoltaics

    NASA Technical Reports Server (NTRS)

    Jackson, B.; Mcguire, P.

    1986-01-01

    The role and some results of the project analysis and integration function in the Flat-plate Solar Array (FSA) Project are presented. Activities included supporting the decision-making process, preparation of plans for project direction, setting goals for project activities, measuring progress within the project, and the development and maintenance of analytical models.

  16. Nanoparticles migration in fractured rocks and affects on contaminant migration

    NASA Astrophysics Data System (ADS)

    Missana, Tiziana; Garcia-Gutierrez, Miguel; Alonso, Ursula

    2014-05-01

    In previous studies, the transport behavior of artificial (gold and latex) and natural (smectite clay) colloids, within a planar fracture in crystalline rock, was analyzed. In order to better understand the effects of colloid size, shape and surface charge on nanoparticle migration and especially on filtration processes on natural rock surfaces, different clay colloids and oxide nanoparticles were selected and their transport studied as a function of the residence time. In all the cases, (a fraction of) the nanoparticles travelled in the fracture as fast as or faster than water (with a retardation factor, Rf ≤ 1) and the observed Rf, was related to the Taylor dispersion coefficient, accounting for colloid size, water velocity and fracture width. However, under most of the cases, in contrast to the behavior of a conservative tracer, colloids recovery was much lower than 100 %. Differences in recovery between different nanoparticles, under similar residence times, were analyzed. In order to evaluate the possible consequences, on contaminant migration, of the presence of nanoparticles in the system, transport tests were carried out with both colloids and sorbing radionuclides. The overall capacity for colloids of enhancing radionuclide migration in crystalline rock fractures is discussed. Acknowledgments: The research leading to these results received funding from EU FP7/2007-2011 grant agreement Nº 295487 (BELBAR, Bentonite Erosion: effects on the Long term performance of the engineered Barrier and Radionuclide Transport) and by the Spanish Government under the project NANOBAG (CTM2011-2797).

  17. Leaving A Legacy: Parental Migration and School Outcomes Among Young Children in the Philippines

    PubMed Central

    Asis, Maruja M.B.; Ruiz-Marave, Cecilia

    2014-01-01

    This article examines the link between parental migration and young children’s education using data from the Philippine country study of the Child Health and Migrant Parents in South-East Asia (CHAMPSEA) Project. The key research question probed here is: what difference does parental migration make to the school outcomes of young children? Specifically, it looks at factors that explain children’s school progression (school pacing) and academic performance (school achievement) using multiple regression analysis. These questions are explored using CHAMPSEA data gathered from a survey of children under 12 years of age and their households in Laguna and Batangas (n=487). The concern that parental absence due to migration can negatively affect the school performance of children is not supported by the study. If parental migration affects school outcomes, it is associated with positive outcomes, or with outcomes which show that children in transnational households are not doing worse than children living with both parents. Positive school outcomes are best associated with a migrant-carer arrangement where fathers work abroad and mothers stay home as carers –children in these households fare very well when it comes to school pacing and school achievement. The study concludes that families and households need to provide both economic and psychological support to enhance the chances that children are at pace with their schooling and are doing well at school. PMID:24954962

  18. Migration and its risks.

    PubMed

    O'brien, P

    1996-01-01

    "This essay applies the theories of Ulrich Beck...to the politics of migration in Germany. In particular, the essay focuses on Beck's notion of the waning influence, indeed even relevancy, of science and scientists regarding postmodern risk phenomena. The essay argues that migration to Germany can be understood as a Beckian risk phenomenon, helping to explain the decreasing influence of social scientists over the politics of migration in the Federal Republic."

  19. A Case Study of the Basic Education Project for the Children of Seasonal Agricultural Workers in the Cukurova Region in Turkey. Mid-Decade Review of Progress towards Education for All.

    ERIC Educational Resources Information Center

    Guner, Barbaros; Simsek, Hasan; Yildirim, Ali

    In 1995, the International Consultative Forum on Education for All commissioned case studies in developing countries as part of a mid-decade review of progress in expanding access to basic education. This paper examines a project in Turkey that provided basic education and health services to the children of seasonal agricultural workers. Between…

  20. Using SAR and GPS for Hazard Management and Response: Progress and Examples from the Advanced Rapid Imaging and Analysis (ARIA) Project

    NASA Astrophysics Data System (ADS)

    Owen, S. E.; Simons, M.; Hua, H.; Yun, S. H.; Agram, P. S.; Milillo, P.; Sacco, G. F.; Webb, F.; Rosen, P. A.; Lundgren, P.; Milillo, G.; Manipon, G. J. M.; Moore, A. W.; Liu, Z.; Polet, J.; Cruz, J.

    2014-12-01

    ARIA is a joint JPL/Caltech project to automate synthetic aperture radar (SAR) and GPS imaging capabilities for scientific understanding, hazard response, and societal benefit. We have built a prototype SAR and GPS data system that forms the foundation for hazard monitoring and response capability, as well as providing imaging capabilities important for science studies. Together, InSAR and GPS have the ability to capture surface deformation in high spatial and temporal resolution. For earthquakes, this deformation provides information that is complementary to seismic data on location, geometry and magnitude of earthquakes. Accurate location information is critical for understanding the regions affected by damaging shaking. Regular surface deformation measurements from SAR and GPS are useful for monitoring changes related to many processes that are important for hazard and resource management such as volcanic deformation, groundwater withdrawal, and landsliding. Observations of SAR coherence change have a demonstrated use for damage assessment for hazards such as earthquakes, tsunamis, hurricanes, and volcanic eruptions. These damage assessment maps can be made from imagery taken day or night and are not affected by clouds, making them valuable complements to optical imagery. The coherence change caused by the damage from hazards (building collapse, flooding, ash fall) is also detectable with intelligent algorithms, allowing for rapid generation of damage assessment maps over large areas at fine resolution, down to the spatial scale of single family homes. We will present the progress and results we have made on automating the analysis of SAR data for hazard monitoring and response using data from the Italian Space Agency's (ASI) COSMO-SkyMed constellation of X-band SAR satellites. Since the beginning of our project with ASI, our team has imaged deformation and coherence change caused by many natural hazard events around the world. We will present progress on our

  1. FURTHER STUDIES ON UNCERTAINTY, CONFOUNDING, AND VALIDATION OF THE DOSES IN THE TECHA RIVER DOSIMETRY SYSTEM: Concluding Progress Report on the Second Phase of Project 1.1

    SciTech Connect

    Degteva, M. O.; Anspaugh, L. R.; Napier, Bruce A.

    2009-10-23

    This is the concluding Progress Report for Project 1.1 of the U.S./Russia Joint Coordinating Committee on Radiation Effects Research (JCCRER). An overwhelming majority of our work this period has been to complete our primary obligation of providing a new version of the Techa River Dosimetry System (TRDS), which we call TRDS-2009D; the D denotes deterministic. This system provides estimates of individual doses to members of the Extended Techa River Cohort (ETRC) and post-natal doses to members of the Techa River Offspring Cohort (TROC). The latter doses were calculated with use of the TRDS-2009D. The doses for the members of the ETRC have been made available to the American and Russian epidemiologists in September for their studies in deriving radiogenic risk factors. Doses for members of the TROC are being provided to European and Russian epidemiologists, as partial input for studies of risk in this population. Two of our original goals for the completion of this nine-year phase of Project 1.1 were not completed. These are completion of TRDS-2009MC, which was to be a Monte Carlo version of TRDS-2009 that could be used for more explicit analysis of the impact of uncertainty in doses on uncertainty in radiogenic risk factors. The second incomplete goal was to be the provision of household specific external doses (rather than village average). This task was far along, but had to be delayed due to the lead investigator’s work on consideration of a revised source term.

  2. Lessons from the motorized migrations

    USGS Publications Warehouse

    Ellis, D.H.; Gee, G.F.; Clegg, K.R.; Duff, J.W.; Lishman, W.A.; Sladen, William J. L.

    2001-01-01

    Ten experiments have been conducted to determine if cranes can be led on migration and if those so trained will repeat migrations on their own. Results have been mixed as we have experienced the mishaps common to pilot studies. Nevertheless, we have learned many valuable lessons. Chief among these are that cranes can be led long distances behind motorized craft (air and ground), and those led over most or the entire route will return north come spring and south in fall to and from the general area of training. However, they will follow their own route. Groups transported south and flown at intervals along the route will migrate but often miss target termini. If certain protocol restrictions are followed, it is possible to make the trained cranes wild, however, the most practical way of so doing is to introduce them into a flock of wild cranes. We project that it is possible to create or restore wild migratory flocks of cranes by first leading small groups from chosen northern to southern termini.

  3. Grande Ronde Model Watershed Program Administration and Habitat Projects, Annual Progress Report, Project Period: Program Administration: January 1, 1997 - December 31, 1997 Habitat Projects: January 1, 1997 - March 31, 1998.

    SciTech Connect

    Noyes, Cecilia; Kuchenbecker, Lyle; Perry, Patty

    1998-10-28

    This agreement provided funding for operation and administration of the Grande Ronde Model Watershed Program including staffing of an Executive Director, Program Planner, and clerical personnel. The contract covers maintaining program services, project planning, subwatershed plans (CRMP's), public involvement and education, interagency coordination/clearing house, monitoring, and technical support activities that have taken place in the Grande Ronde basin. Cost-share has been received from the Bureau of Reclamation and the Governor's Watershed Enhancement Board.

  4. Resource Conservation and Recovery Act ground-water monitoring projects for Hanford facilities: Progress report for the period July 1 to September 30, 1988: Volume 1, Text

    SciTech Connect

    Fruland, R.M.; Bates, D.J.; Lundgren, R.E.

    1989-02-01

    This report describes the progress of 12 Hanford ground-water monitoring projects for the period July 1 to September 30, 1988. During this quarter, field activities at the 300 Area process trenches, the Nonradioactive Dangerous Waste Landfill, the 183-H Solar Evaporation Basins, the 1324-N/NA Surface Impoundment and Percolation Ponds, the 1301-N and 1325-N Liquid Waste Disposal Facilities, and the 216-A-36B Crib consisted of ground-water sampling and analyses, and water-level monitoring. The 200 Area Low-Level Burial Grounds section includes well development data, sediment analysis, and water-level measurements. Ground-water sampling was begun at this site, and results will be included in next quarter's report. Twelve new wells were installed during the quarter, two at the 216-A-29 Ditch, size at the 216-A-10 Crib, and four at the 216-B-3 Pond. Preliminary characterization data for these new wells are included in this report. Driller's logs and other drilling and site characterization data will be provided in the next quarterly report. At the 2101-M Pond, construction was completed on four wells, and initial ground-water samples were taken. The drilling logs, geophysical logging data, and as-built diagrams are included in this report in Volume 2. 19 refs., 24 figs., 39 tabs.

  5. Cell migration, freshly squeezed.

    PubMed

    Welch, Matthew D

    2015-02-12

    Migrating cells exhibit distinct motility modes and can switch between modes based on chemical or physical cues. Liu et al. and Ruprecht et al. now describe how confinement and contractility influence motility mode plasticity and instigate a mode termed stable bleb migration in embryonic and tumor cells.

  6. Orion Progress - Spring 2010

    NASA Video Gallery

    NASA and contractor teams are designing, building and testing the next generation human spacecraft Orion. Progress on Orion is highlighted by employees working on the project, along with video of t...

  7. Migration and Environmental Hazards

    PubMed Central

    Hunter, Lori M.

    2011-01-01

    Losses due to natural hazards (e.g., earthquakes, hurricanes) and technological hazards (e.g., nuclear waste facilities, chemical spills) are both on the rise. One response to hazard-related losses is migration, with this paper offering a review of research examining the association between migration and environmental hazards. Using examples from both developed and developing regional contexts, the overview demonstrates that the association between migration and environmental hazards varies by setting, hazard types, and household characteristics. In many cases, however, results demonstrate that environmental factors play a role in shaping migration decisions, particularly among those most vulnerable. Research also suggests that risk perception acts as a mediating factor. Classic migration theory is reviewed to offer a foundation for examination of these associations. PMID:21886366

  8. Project MAC Progress Report 11

    DTIC Science & Technology

    1974-12-01

    INTRODUCTION In the report submitted by this group (formerly called " Educational Computer Systems") for 1971-72 it was announced with the...algebraic manipulation will be needed. We know of no easy way to surmount the educational problems that are encountered in such areas. In the past...Advanced Study Institute, Aberystwyth, Wales, August 1973. 2. Licklider, J. C. R., "Potential of Networking for Research and Education ," Networks for

  9. Project SQUID. Quarterly Progress Report

    DTIC Science & Technology

    1950-04-01

    M h- »- 4 J DUCT WAL L TEMPER ATURE...1 V i i * $111 1 i || | i i i | j | \\ [ ! ; ! o | T I r ■ | " j \\ 1 i M 1 \\ T j 1 11 ’ 1 ! j ...i ’ i I\\l M ! Ik j |\\| ; I ; N IT 1*1 1 i 1 B ’ill 1 \\ r w i i\\ i i i \\ 1 \\ ’ \\

  10. Project SQUID: Quarterly Progress Report

    DTIC Science & Technology

    1950-07-01

    effect of mixing temperature upon the ignition lag of the bipropellant system, white fuming nitric acid and furfuryl alcohol , has been completed...in molecular activity with decreasing mixing temrerature and the poor mixing resulting from the marked increase in viscosity of the furfuryl alcohol ...micrometer mounted on the outside of the tubeo A traveling thermocouple constructed with No. 40B and S copper and constantan wires butt-welded together to

  11. Foam shell project: Progress report

    SciTech Connect

    Overturf, G.; Reibold, B.; Cook, B.; Schroen-Carey, D.

    1994-03-25

    The authors report on their work to produce a foam shell target for two possible applications: (1) as liquid-layered cryogenic target on Omega Upgrade, and (2) as a back-up design for the NIF. This target consists of a roughly 1 mm diameter and 100 {mu}m thick spherical low-density foam shell surrounding a central void. The foam will be slightly overfilled with liquid D{sub 2} or DT, the overfilled excess being symmetrically distributed on the inside of the shell and supported by thermal gradient techniques. The outside of the foam is overcoated with full density polymer which must be topologically smooth. The technology for manufacturing this style of foam shell involves microencapsulation techniques and has been developed by the Japanese at ILE. Their goal is to determine whether this technology can be successfully adapted to meet US ICF objectives. To this end a program of foam shell development has been initiated at LLNL in collaboration with both the General Atomics DOE Target Fabrication Contract Corporation and the Target Fabrication Group at LLE.

  12. Project SQUID. Quarterly Progress Report

    DTIC Science & Technology

    1948-04-01

    No.30 (C, 1.07%; Ni, 4.96%; Mn, 0.48%; Si, 0.41%) to determine its suitability for cold forming. i 20 Tensile tests, bending tests, and drop ... oil bath heater and a control panel for the apparatus were installed. A number of heating runs were made to determine the time required to reach...B. Edelman, Baton Rouge, Louisiana. 20. Prof. Clark Millikan , California Institute of Technology. 21. Prof. R. Folsom, University of California. 22

  13. Project SQUID. Quarterly Progress Report

    DTIC Science & Technology

    1948-10-01

    the problem of flow in a laminar boundary layer with pressure drop in the direction of flow has been calculated. A study of heat trans- fer in the...in this investiga- tion will be given in a Technical Memorandum. The problem of flow in a laminar boundary layer with pressure drop in the...boundary layer thickness as a function of length in the direction of flow is carried out for the case of linear pressure drop . EXPEHMWAL WOHK The

  14. Project SQUID. Quarterly Progress Report

    DTIC Science & Technology

    1949-07-01

    allowed to remain in contact for 91.3 seconds before the reaction was stopped. A dark red oil weighing 2 g was isolated. This oil contained...nitrogen and gave reactions characteristic of a nitro-compound. When puri- fication was attempted by distillation, the oil smoothly decomposed intc...a viscous black oil . Because of the complexity of the composition of AN-F-58 and the small quantities of materials used, the products of the

  15. Migration and AIDS.

    PubMed

    1998-01-01

    This article presents the perspectives of UNAIDS and the International Organization for Migration (IOM) on migration and HIV/AIDS. It identifies research and action priorities and policy issues, and describes the current situation in major regions of the world. Migration is a process. Movement is enhanced by air transport, rising international trade, deregulation of trade practices, and opening of borders. Movements are restricted by laws and statutes. Denial to freely circulate and obtain asylum is associated with vulnerability to HIV infections. A UNAIDS policy paper in 1997 and IOM policy guidelines in 1988 affirm that refugees and asylum seekers should not be targeted for special measures due to HIV/AIDS. There is an urgent need to provide primary health services for migrants, voluntary counseling and testing, and more favorable conditions. Research is needed on the role of migration in the spread of HIV, the extent of migration, availability of health services, and options for HIV prevention. Research must be action-oriented and focused on vulnerability to HIV and risk taking behavior. There is substantial mobility in West and Central Africa, economic migration in South Africa, and nonvoluntary migration in Angola. Sex workers in southeast Asia contribute to the spread. The breakup of the USSR led to population shifts. Migrants in Central America and Mexico move north to the US where HIV prevalence is higher.

  16. STRUCTURAL ECONOMIC CHANGE AND INTERNATIONAL MIGRATION FROM MEXICO AND POLAND

    PubMed Central

    Massey, Douglas S.; Kalter, Frank; Pren, Karen A.

    2010-01-01

    In this article we use uniquely comparable data sets from two very different settings to examine how exogenous economic transformations affect the likelihood and selectivity of international out-migration. Specifically, we use data from the Mexican Migration Project to construct event history files predicting first U.S. trips from seven communities in the state of Veracruz, which until recently sent very few migrants abroad. Similarly, using data from the Polish Migration Project, we derive comparable event history files predicting first trips to Germany from four Polish communities, which also sent few migrants abroad before the 1980s. Our analyses suggest that the onset of structural adjustment in both places had a significant effect in raising the probability of international migration, even when controlling for a set of standard variables specified by other theories to influence migration propensity, such as the size of the binational income gap and various indicators of human and social capital. PMID:21765550

  17. Measuring Progress on the Control of Porcine Reproductive and Respiratory Syndrome (PRRS) at a Regional Level: The Minnesota N212 Regional Control Project (Rcp) as a Working Example

    PubMed Central

    Valdes-Donoso, Pablo; Jarvis, Lovell S.; Wright, Dave; Alvarez, Julio; Perez, Andres M.

    2016-01-01

    Due to the highly transmissible nature of porcine reproductive and respiratory syndrome (PRRS), implementation of regional programs to control the disease may be critical. Because PRRS is not reported in the US, numerous voluntary regional control projects (RCPs) have been established. However, the effect of RCPs on PRRS control has not been assessed yet. This study aims to quantify the extent to which RCPs contribute to PRRS control by proposing a methodological framework to evaluate the progress of RCPs. Information collected between July 2012 and June 2015 from the Minnesota Voluntary Regional PRRS Elimination Project (RCP-N212) was used. Demography of premises (e.g. composition of farms with sows = SS and without sows = NSS) was assessed by a repeated analysis of variance. By using general linear mixed-effects models, active participation of farms enrolled in the RCP-N212, defined as the decision to share (or not to share) PRRS status, was evaluated and used as a predictor, along with other variables, to assess the PRRS trend over time. Additionally, spatial and temporal patterns of farmers’ participation and the disease dynamics were investigated. The number of farms enrolled in RCP-N212 and its geographical coverage increased, but the proportion of SS and NSS did not vary significantly over time. A significant increasing (p<0.001) trend in farmers’ decision to share PRRS status was observed, but with NSS producers less willing to report and a large variability between counties. The incidence of PRRS significantly (p<0.001) decreased, showing a negative correlation between degree of participation and occurrence of PRRS (p<0.001) and a positive correlation with farm density at the county level (p = 0.02). Despite a noted decrease in PRRS, significant spatio-temporal patterns of incidence of the disease over 3-weeks and 3-kms during the entire study period were identified. This study established a systematic approach to quantify the effect of RCPs on PRRS

  18. NERI PROJECT 99-119."A NEW PARADIGM FOR AUTOMATIC DEVELOPMENT OF HIGHLY RELIABLE CONTROL ARCHITECTURES FOR NUCLEAR POWER PLANTS."PHASE-1 PROGRESS REPORT

    SciTech Connect

    March-Leuba, J.A.

    2000-08-29

    This report describes the tasks performed and the progress made during Phase 1 of the DOE-NERI project number 99-119 entitled ''Automatic Development of Highly Reliable Control Architecture for Future Nuclear Power Plants''. This project is a collaboration effort between the Oak Ridge National Laboratory (ORNL,) The University of Tennessee, Knoxville (UTK) and the North Carolina State University (NCSU). ORNL is the lead organization and is responsible for the coordination and integration of all work. This research focuses on the development of methods for automated generation of control systems that can be traced directly to the design requirements for the life of the plant. Our final goal is to ''capture'' the design requirements inside a ''control engine'' during the design phase. This control engine is, then, not only capable of designing automatically the initial implementation of the control system, but it also can confirm that the original design requirements are still met during the life of the plant as conditions change. This control engine captures the high-level requirements and stress factors that the control system must survive (e.g. a list of transients, or a requirement to withstand a single failure). The control engine, then, is able to generate automatically the control-system algorithms and parameters that optimize a design goal and satisfy all requirements. As conditions change during the life of the plant (e.g. component degradation, or subsystem failures) the control engine automatically ''flags'' that a requirement is not satisfied, and it can even suggest a modified configuration that would satisfy it. This control engine concept is shown schematically in Fig. 1. The implementation of this ''control-engine'' design methodology requires the following steps, which are described in detail in the attachments to this report: (1) Selection of Design Requirements Related to Control System Performance; (2) Implementation of Requirements in

  19. Measuring Progress on the Control of Porcine Reproductive and Respiratory Syndrome (PRRS) at a Regional Level: The Minnesota N212 Regional Control Project (Rcp) as a Working Example.

    PubMed

    Valdes-Donoso, Pablo; Jarvis, Lovell S; Wright, Dave; Alvarez, Julio; Perez, Andres M

    2016-01-01

    Due to the highly transmissible nature of porcine reproductive and respiratory syndrome (PRRS), implementation of regional programs to control the disease may be critical. Because PRRS is not reported in the US, numerous voluntary regional control projects (RCPs) have been established. However, the effect of RCPs on PRRS control has not been assessed yet. This study aims to quantify the extent to which RCPs contribute to PRRS control by proposing a methodological framework to evaluate the progress of RCPs. Information collected between July 2012 and June 2015 from the Minnesota Voluntary Regional PRRS Elimination Project (RCP-N212) was used. Demography of premises (e.g. composition of farms with sows = SS and without sows = NSS) was assessed by a repeated analysis of variance. By using general linear mixed-effects models, active participation of farms enrolled in the RCP-N212, defined as the decision to share (or not to share) PRRS status, was evaluated and used as a predictor, along with other variables, to assess the PRRS trend over time. Additionally, spatial and temporal patterns of farmers' participation and the disease dynamics were investigated. The number of farms enrolled in RCP-N212 and its geographical coverage increased, but the proportion of SS and NSS did not vary significantly over time. A significant increasing (p<0.001) trend in farmers' decision to share PRRS status was observed, but with NSS producers less willing to report and a large variability between counties. The incidence of PRRS significantly (p<0.001) decreased, showing a negative correlation between degree of participation and occurrence of PRRS (p<0.001) and a positive correlation with farm density at the county level (p = 0.02). Despite a noted decrease in PRRS, significant spatio-temporal patterns of incidence of the disease over 3-weeks and 3-kms during the entire study period were identified. This study established a systematic approach to quantify the effect of RCPs on PRRS

  20. Phenotypic and functional changes in peripheral blood monocytes during progression of human immunodeficiency virus infection. Effects of soluble immune complexes, cytokines, subcellular particulates from apoptotic cells, and HIV-1-encoded proteins on monocytes phagocytic function, oxidative burst, transendothelial migration, and cell surface phenotype.

    PubMed Central

    Trial, J; Birdsall, H H; Hallum, J A; Crane, M L; Rodriguez-Barradas, M C; de Jong, A L; Krishnan, B; Lacke, C E; Figdor, C G; Rossen, R D

    1995-01-01

    We postulated that changes in the cell surface display of molecules that facilitate cell-cell and cell-matrix adhesions may reflect the changing immunosurveillance capacity of blood monocytes during progression of human immunodeficiency virus (HIV) infections. In Centers for Disease Control (CDC) stage A patients, whose monocytes' ability to phagocytose bacteria and generate reactive oxygen intermediates is often increased, the frequency of monocytes expressing CD49d, HLA-DP, HLA-DQ, and an activation epitope of CD11a/CD18 was increased and monocyte transendothelial migration was unimpaired. In CDC stage B/C patients, whose monocytes' ability to phagocytose bacteria and migrate across confluent endothelial monolayers was diminished, surface expression of CD49e and CD62L and the percentage of monocytes expressing CD18, CD11a, CD29, CD49e, CD54, CD58, CD31, and HLA-I were significantly decreased. Incubating normal donor monocytes with immune complexes in vitro reproduced the phenotypic and functional abnormalities seen in stage B/C patients. By contrast, in vitro stimulation with subcellular particulates released by apoptotic lymphocytes reproduced changes seen in stage A patients' monocytes. Although circulating monocytes appear to be activated at all stages, these data suggest that the high levels of circulating immune complexes, found predominantly in the later stages of HIV infection, may be particularly instrumental in reducing the monocyte's capacity to maintain surveillance against infection. Images PMID:7706478

  1. Tetraspanins in Cell Migration

    PubMed Central

    Jiang, Xupin; Zhang, Jiaping; Huang, Yuesheng

    2015-01-01

    Tetraspanins are a superfamily of small transmembrane proteins that are expressed in almost all eukaryotic cells. Through interacting with one another and with other membrane and intracellular proteins, tetraspanins regulate a wide range of proteins such as integrins, cell surface receptors, and signaling molecules, and thereby engage in diverse cellular processes ranging from cell adhesion and migration to proliferation and differentiation. In particular, tetraspanins modulate the function of proteins involved in all determining factors of cell migration including cell–cell adhesion, cell–ECM adhesion, cytoskeletal protrusion/contraction, and proteolytic ECM remodeling. We herein provide a brief overview of collective in vitro and in vivo studies of tetraspanins to illustrate their regulatory functions in the migration and trafficking of cancer cells, vascular endothelial cells, skin cells (keratinocytes and fibroblasts), and leukocytes. We also discuss the involvement of tetraspanins in various pathologic and remedial processes that rely on cell migration and their potential value as targets for therapeutic intervention. PMID:26091149

  2. Neuronal Migration Disorders

    MedlinePlus

    ... Understanding Sleep The Life and Death of a Neuron Order Publications Support Resources Patient Organizations Professional Societies ... birth defects caused by the abnormal migration of neurons in the developing brain and nervous system. In ...

  3. Indonesia's migration transition.

    PubMed

    Hugo, G

    1995-01-01

    This article describes population movements in Indonesia in the context of rapid and marked social and economic change. Foreign investment in Indonesia is increasing, and global mass media is available to many households. Agriculture is being commercialized, and structural shifts are occurring in the economy. Educational levels are increasing, and women's role and status are shifting. Population migration has increased over the decades, both short and long distance, permanent and temporary, legal and illegal, and migration to and between urban areas. This article focuses specifically on rural-to-urban migration and international migration. Population settlements are dense in the agriculturally rich inner areas of Java, Bali, and Madura. Although the rate of growth of the gross domestic product was 6.8% annually during 1969-94, the World Bank ranked Indonesia as a low-income economy in 1992 because of the large population size. Income per capita is US $670. Indonesia is becoming a large exporter of labor to the Middle East, particularly women. The predominance of women as overseas contract workers is changing women's role and status in the family and is controversial due to the cases of mistreatment. Malaysia's high economic growth rate of over 8% per year means an additional 1.3 million foreign workers and technicians are needed. During the 1980s urban growth increased at a very rapid rate. Urban growth tended to occur along corridors and major transportation routes around urban areas. It is posited that most of the urban growth is due to rural-to-urban migration. Data limitations prevent an exact determination of the extent of rural-to-urban migration. More women are estimated to be involved in movements to cities during the 1980s compared to the 1970s. Recruiters and middlemen have played an important role in rural-to-urban migration and international migration.

  4. Seasonal changes in the altitudinal distribution of nocturnally migrating birds during autumn migration.

    PubMed

    La Sorte, Frank A; Hochachka, Wesley M; Farnsworth, Andrew; Sheldon, Daniel; Van Doren, Benjamin M; Fink, Daniel; Kelling, Steve

    2015-12-01

    Wind plays a significant role in the flight altitudes selected by nocturnally migrating birds. At mid-latitudes in the Northern Hemisphere, atmospheric conditions are dictated by the polar-front jet stream, whose amplitude increases in the autumn. One consequence for migratory birds is that the region's prevailing westerly winds become progressively stronger at higher migration altitudes. We expect this seasonality in wind speed to result in migrants occupying progressively lower flight altitudes, which we test using density estimates of nocturnal migrants at 100 m altitudinal intervals from 12 weather surveillance radar stations located in the northeastern USA. Contrary to our expectations, median migration altitudes deviated little across the season, and the variance was lower during the middle of the season and higher during the beginning and especially the end of the season. Early-season migrants included small- to intermediate-sized long-distance migrants in the orders Charadriiformes and Passeriformes, and late-season migrants included large-bodied and intermediate-distance migrants in the order Anseriformes. Therefore, seasonality in the composition of migratory species, and related variation in migration strategies and behaviours, resulted in a convex-concave bounded distribution of migration altitudes. Our results provide a basis for assessing the implications for migratory bird populations of changes in mid-latitude atmospheric conditions probably occurring under global climate change.

  5. Project: "Project!"

    ERIC Educational Resources Information Center

    Grayson, Katherine

    2007-01-01

    In November 2006, the editors of "Campus Technology" launched their first-ever High-Resolution Projection Study, to find out if the latest in projector technology could really make a significant difference in teaching, learning, and educational innovation on US campuses. The author and her colleagues asked campus educators,…

  6. ISABELLE: a progress report

    SciTech Connect

    Hahn, H

    1980-01-01

    This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed.

  7. Radionuclide migration in clayrock host formations for deep geological disposal of radioactive waste: advances in process understanding and up-scaling methods resulting from the EC integrated project `Funmig

    NASA Astrophysics Data System (ADS)

    Altmann, S.; Tournassat, C.; Goutelard, F.; Parneix, J. C.; Gimmi, T.; Maes, N.

    2009-04-01

    One of the ‘pillars' supporting Safety Cases for deep geological disposal of radioactive waste in clayrock formations is the knowledge base regarding radionuclide (Rn) retention by sorption and diffusion-driven transport which is why the EC integrated project ‘Funmig' focused a major part of its effort on advancing understanding of these two macroscopic phenomena. This talk presents some of the main results of this four year effort (2005-2008). One of the keys to understanding diffusion-driven transport of anionic and cationic radionuclide species in clayrocks lies in a detailed understanding of the phenomena governing Rn total concentration and speciation (dissolved, adsorbed) in the different types of pore spaces present in highly-compacted masses of permanently charged clay minerals. Work carried out on a specifically synthesized montmorillonite (a model for the clay mineral fraction in clayrocks) led to development, and preliminary experimental validation, of a conceptually coherent set of theoretical models (molecular dynamics, electrostatic double layer, thermodynamic) describing dissolved ion and water solvent behavior in this material. This work, complemented by the existing state of the art, provides a sound theoretical basis for explaining such important phenomena as anion exclusion, cation exchange and the diffusion behavior of anions, weakly sorbing cations and water tracers. Concerning the behavior of strongly sorbing and/or redox-reactive radionuclides in clay systems, project research improved understanding of the nature of sorption reactions and sorbed species structure for key radioelements, or analogues (U, Se, Eu, Sm, Yb, Nd) on the basal surfaces and in the interlayers of synthetic or purified clay minerals. A probable mechanism for Se(IV) retention by reduction to Se° in Fe2+-containing clays was brought to light; this same process was also studied on the Callovo-Oxfordien clayrock targeted by the French radwaste management program. The

  8. [International migration in Latin America].

    PubMed

    Pellegrino, A

    1995-12-01

    Trends in international migration in Latin America are reviewed using data from published sources. Aspects considered include historical views; migration according to occupational status and educational level; migration to the United States; migration characteristics in different regions of Latin America; and the crisis of the 1980s and its impact on population distribution.

  9. Environmental concerns and international migration.

    PubMed

    Hugo, G

    1996-01-01

    "This article focuses on international migration occurring as a result of environmental changes and processes. It briefly reviews attempts to conceptualize environment-related migration and then considers the extent to which environmental factors have been and may be significant in initiating migration. Following is an examination of migration as an independent variable in the migration-environment relationship. Finally, ethical and policy dimensions are addressed."

  10. Modeling Quasi-Static and Fatigue-Driven Delamination Migration

    NASA Technical Reports Server (NTRS)

    De Carvalho, N. V.; Ratcliffe, J. G.; Chen, B. Y.; Pinho, S. T.; Baiz, P. M.; Tay, T. E.

    2014-01-01

    An approach was proposed and assessed for the high-fidelity modeling of progressive damage and failure in composite materials. It combines the Floating Node Method (FNM) and the Virtual Crack Closure Technique (VCCT) to represent multiple interacting failure mechanisms in a mesh-independent fashion. Delamination, matrix cracking, and migration were captured failure and migration criteria based on fracture mechanics. Quasi-static and fatigue loading were modeled within the same overall framework. The methodology proposed was illustrated by simulating the delamination migration test, showing good agreement with the available experimental data.

  11. Brazilian population 1982: growth, migration, race, religion.

    PubMed

    Sanders, T G

    1982-01-01

    The rate of population increase dropped to less than 2.5% annually in Brazil between 1970-80, but 26 million more people were born. The 1980 census also provides details of continuing urbanization, settlement of the farthest frontiers, and changes in racial composition. The direct cause of the drop in population increase was a drop of about 15% in the fertility rate that had been projected for the decade. Brazil's rate of population increase declined impressively despite the fact that the country continued to make progress in reducing mortality. The greatest improvement occurred between 1930-60. The mortality rate averaged 20.9/1000 between 1940-50 but dropped to 14.2/1000 between 1950-60. Even though the crude death rate dropped 28% in the 1970-80 decade and each child born in 1980 can expect to live 6.5 years longer than a child born in 1970, the life expectancy of 62 years compares with Colombia and El Salvador, which are much poorer countries. In Brazil as a whole the crude birthrate in the 15-19 age group was 66/1000 in 1980. It was 46/1000 in 1970, an increase of nearly 50%. In urban areas the rate increased from 37/1000 to 57/1000 and in the countryside from 59/1000 to 89/1000. The crude birthrate went down slightly in Brazil from 1970-80 from 34 to 32/1000. The total fertility rate (TFR) dropped in the same period from 4.9ll to 3.983. The question that arises is whether fertility rates will increase, with women in the youngest age group continuing to have more children during their reproductive years. Internal migration plays a major role in the distribution of the population. Between 1970-80 there were changes in the migration pattern from the previous decade. All the rapidly growing areas, defined as the frontier, have high fertility rates, but much of their growth results from migration. Between 1960-70 and 1970-80 the most rapidly growing areas of the frontier changed. Few are aware of the extent to which Brazil is becoming a country of large cities

  12. Migration and pension.

    PubMed

    Razin, A; Sadka, E

    1998-11-01

    "Migration has important implications for the financial soundness of the pension system.... While it is common sense to expect that young migrants, even if low-skilled, can help society pay the benefits to the currently elderly, it may nevertheless be reasonable to argue that these migrants would adversely affect current young since, after all, the migrants are net beneficiaries of the welfare state. In contrast to the adverse effects of low skilled migration in a static model, [the authors] show that in a Samuelsonian overlapping generations model...migration is a Pareto-improving measure. All the existing income (low and high) and age (young and old) groups living at the time of the migrant's arrival would be better off."

  13. More myths of migration.

    PubMed

    Basch, L; Lerner, G

    1986-01-01

    This paper discusses some of the myths of migration. The 5 myths presented are: 1) racism has little to do with the causes of migration and does not necessarily impede the adjustment or success of migrants; 2) in areas where there is a strong feminist movement and trade unions, migrant women receive their support and can count on the solidarity of these organizations; 3) transnational corporations are positive forces in the developing countries where they operate--not only do they provide these states with new sources of capital, but they also impart new industrial skills to the labor force; 4) migration today is essentially short-term in nature--it therefore does not have a strong impact on family life; and 5) most migrants cluster together in ethnic enclaves which provide a strong source of support and diminish dislocation inherent in the migrant process.

  14. Migration from Packaging Materials

    NASA Astrophysics Data System (ADS)

    Meulenaer, B. De

    Various chemical compounds can be present in foodstuffs which may induce health problems in humans. The origin of these compounds can be very diverse. Mathematical modeling can sometimes be used to predict the concentration of these chemicals in the food. Particularly for compounds which are produced in the food during, e.g., processing and for compounds which migrate from a food contact material this technique can be very fruitful. For the former type of compounds, classical chemical kinetics can be applied. In this contribution, the modeling of the migration from polymeric food contact materials is considered. This migration phenomenon can be modeled mathematically since the physical processes which govern this process are very well studied and understood. Therefore, initially some of these fundamentals will be discussed in more detail.

  15. Detecting interstellar migrations

    NASA Astrophysics Data System (ADS)

    Matloff, Gregory L.; Pazmino, John

    1997-01-01

    Interstellar migrations may occur when a civilization's star enters the red giant phase, thereby dooming the life-bearing planet. Ecologically self-contained 'world ships', massing billions of kilograms and propelled by hyperthin, space manufactured solar sails thousands of kilometers in diameter unfurled near the home star are possible vehicles to transfer a threatened civilization to a neighboring star. Consideration of the nearest red giants reveals that Pollux is the nearest formerly solar-type red giant. Known stellar neighbors of Pollux are surveyed to determine likely directions for an interstellar migration departing Pollux. Such migrations might consist of many world ships launched over millennia on voyages of about 1000 terrestrial-year duration; discovery of such events will be serendipitous. The difficulties of observing solar-sail star ships near Pollux are considered. A facility dedicated to imaging extrasolar planets within 10 parsecs might be capable of detecting these large spacecraft.

  16. Climate Change as Migration Driver from Rural and Urban Mexico

    PubMed Central

    Hunter, Lori M.; Runfola, Daniel M.; Riosmena, Fernando

    2015-01-01

    Studies investigating migration as a response to climate variability have largely focused on rural locations to the exclusion of urban areas. This lack of urban focus is unfortunate given the sheer numbers of urban residents and continuing high levels of urbanization. To begin filling this empirical gap, this study investigates climate change impacts on U.S.-bound migration from rural and urban Mexico, 1986–1999. We employ geostatistical interpolation methods to construct two climate change indices, capturing warm and wet spell duration, based on daily temperature and precipitation readings for 214 weather stations across Mexico. In combination with detailed migration histories obtained from the Mexican Migration Project, we model the influence of climate change on household-level migration from 68 rural and 49 urban municipalities. Results from multilevel event-history models reveal that a temperature warming and excessive precipitation significantly increased international migration during the study period. However, climate change impacts on international migration is only observed for rural areas. Interactions reveal a causal pathway in which temperature (but not precipitation) influences migration patterns through employment in the agricultural sector. As such, climate-related international migration may decline with continued urbanization and the resulting reductions in direct dependence of households on rural agriculture. PMID:26692890

  17. Climate Change as Migration Driver from Rural and Urban Mexico.

    PubMed

    Nawrotzki, Raphael J; Hunter, Lori M; Runfola, Daniel M; Riosmena, Fernando

    2015-11-01

    Studies investigating migration as a response to climate variability have largely focused on rural locations to the exclusion of urban areas. This lack of urban focus is unfortunate given the sheer numbers of urban residents and continuing high levels of urbanization. To begin filling this empirical gap, this study investigates climate change impacts on U.S.-bound migration from rural and urban Mexico, 1986-1999. We employ geostatistical interpolation methods to construct two climate change indices, capturing warm and wet spell duration, based on daily temperature and precipitation readings for 214 weather stations across Mexico. In combination with detailed migration histories obtained from the Mexican Migration Project, we model the influence of climate change on household-level migration from 68 rural and 49 urban municipalities. Results from multilevel event-history models reveal that a temperature warming and excessive precipitation significantly increased international migration during the study period. However, climate change impacts on international migration is only observed for rural areas. Interactions reveal a causal pathway in which temperature (but not precipitation) influences migration patterns through employment in the agricultural sector. As such, climate-related international migration may decline with continued urbanization and the resulting reductions in direct dependence of households on rural agriculture.

  18. Understanding Population Projections.

    ERIC Educational Resources Information Center

    Haub, Carl

    1987-01-01

    Population projections are "what if" computational exercises. Given selected assumptions about future trends in fertility, mortality, and migration, population trends can be projected. Government and business planners need this information, and they also require enough time to put facilities in place to meet future needs. Everyone benefits from a…

  19. Analysing immune cell migration.

    PubMed

    Beltman, Joost B; Marée, Athanasius F M; de Boer, Rob J

    2009-11-01

    The visualization of the dynamic behaviour of and interactions between immune cells using time-lapse video microscopy has an important role in modern immunology. To draw robust conclusions, quantification of such cell migration is required. However, imaging experiments are associated with various artefacts that can affect the estimated positions of the immune cells under analysis, which form the basis of any subsequent analysis. Here, we describe potential artefacts that could affect the interpretation of data sets on immune cell migration. We propose how these errors can be recognized and corrected, and suggest ways to prevent the data analysis itself leading to biased results.

  20. [Migration, climate and health].

    PubMed

    Tellier, Siri; Carballo, Manuel; Calballo, Manuel

    2009-10-26

    Many tentative connections have been postulated between migration and climate. This article points to rural-urban migration, particularly into low elevation urban slums prone to flooding as an issue needing urgent attention by health professionals. It also notes the no-man's land in which environmental refugees find themselves and the consequences this may have. Finally, it points to the urgent need to reform health systems in both developing and developed countries to adapt to rapidly changing disease patterns and to become more responsive to them.