ExoMol line lists - XXII. The rotation-vibration spectrum of silane up to 1200 K

NASA Astrophysics Data System (ADS)

Owens, A.; Yachmenev, A.; Thiel, W.; Tennyson, J.; Yurchenko, S. N.

2017-11-01

A variationally computed 28SiH4 rotation-vibration line list applicable for temperatures up to T = 1200 K is presented. The line list, called OY2T, considers transitions with rotational excitation up to J = 42 in the wavenumber range 0-5000 cm-1 (wavelengths λ > 2 μm). Just under 62.7 billion transitions have been calculated between 6.1 million energy levels. Rovibrational calculations have utilized a new `spectroscopic' potential energy surface determined by empirical refinement to 1452 experimentally derived energy levels up to J = 6, and a previously reported ab initio dipole moment surface. The temperature-dependent partition function of silane, the OY2T line list format, and the temperature dependence of the OY2T line list are discussed. Comparisons with the PNNL spectral library and other experimental sources indicate that the OY2T line list is robust and able to accurately reproduce weaker intensity features. The full line list is available from the ExoMol data base and the CDS data base.

Pembrolizumab as second-line therapy in non-small cell lung cancer in northern Norway: budget impact and expected gain—a model-based analysis

PubMed Central

Norum, Jan; Antonsen, Margareth Aarag; Tollåli, Terje; Al-Shibli, Khalid; Andersen, Gry; Svanqvist, Kristin Helene; Helbekkmo, Nina

2017-01-01

Background Pembrolizumab is a new drug approved in several countries for second-line therapy in non-small cell lung cancer (NSCLC) being programmed cell death ligand (PD-L1) positive. This drug has a high cost, and the cost-effectiveness ratio has been debated. Patients and methods The budget impact to the Northern Norwegian Regional Health Authority trust of implementing pembrolizumab in second-line therapy in patients with PD-L1-positive NSCLC was calculated. A model was developed employing data from the Cancer Registry of Norway, the KEYNOTE-010 study, the price list from The Hospital Pharmacy of North Norway, the cost of analysing PD-L1 expression and the cost of travelling. Today’s cost of second-line therapy was compared with the new standard employing pembrolizumab. The sale price of pembrolizumab in Norway was not published due to price confidentiality. Norwegian krone (NKr) was converted into Euros (€) at a rate of 1€=Nkr 8.8138. (Bank of Norway, 21 February 2017). Results 105 new patients were identified available for pembrolizumab per year. The annual cost of pembrolizumab was €5.2 million, hospital pharmacy administration costs €0.1 million, PD-L1 testing €0.3 million, oncologist/pulmonologist/nurses €0.2 million, radiology €0.06 million and transportation €0.4 million. Savings due to avoided present second-line therapy was calculated €0.4 million. Consequently, the cost of implementing pembrolizumab was €5.5 million and the annual budget impact was €5.0 million. A mean gain of at least 9 months per patient treated was necessary to make pembrolizumab cost-effective. Conclusions The net budget impact of pembrolizumab was €5.0 million. The expenditure could not be indicated cost-effective. Price confidentiality is a growing problem in health economics and it has become a ‘menu without prices’ setting. PMID:29209527

Strengthening Software Authentication with the ROSE Software Suite

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G

2006-06-15

Many recent nonproliferation and arms control software projects include a software authentication regime. These include U.S. Government-sponsored projects both in the United States and in the Russian Federation (RF). This trend toward requiring software authentication is only accelerating. Demonstrating assurance that software performs as expected without hidden ''backdoors'' is crucial to a project's success. In this context, ''authentication'' is defined as determining that a software package performs only its intended purpose and performs said purpose correctly and reliably over the planned duration of an agreement. In addition to visual inspections by knowledgeable computer scientists, automated tools are needed to highlightmore » suspicious code constructs, both to aid visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary and not extensible. An open-source, extensible tool can be customized to the unique needs of each project (projects can have both common and custom rules to detect flaws and security holes). Any such extensible tool has to be based on a complete language compiler. ROSE is precisely such a compiler infrastructure developed within the Department of Energy (DOE) and targeted at the optimization of scientific applications and user-defined libraries within large-scale applications (typically applications of a million lines of code). ROSE is a robust, source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C and C++ (handling the full C, C99, C++ languages and with current collaborations to support Fortran90). We propose to extend ROSE to address a number of security-specific requirements, and apply it to software authentication for nonproliferation and arms control projects.« less

Critical care medicine as a distinct product line with substantial financial profitability: the role of business planning.

PubMed

Bekes, Carolyn E; Dellinger, R Phillip; Brooks, Daniel; Edmondson, Robert; Olivia, Christopher T; Parrillo, Joseph E

2004-05-01

As academic health centers face increasing financial pressures, they have adopted a more businesslike approach to planning, particularly for discrete "product" or clinical service lines. Since critical care typically has been viewed as a service provided by a hospital, and not a product line, business plans have not historically been developed to expand and promote critical care. The major focus when examining the finances of critical care has been cost reduction, not business development. We hypothesized that a critical care business plan can be developed and analyzed like other more typical product lines and that such a critical care product line can be profitable for an institution. In-depth analysis of critical care including business planning for critical care services. Regional academic health center in southern New Jersey. None. As part of an overall business planning process directed by the Board of Trustees, the critical care product line was identified by isolating revenue, expenses, and profitability associated with critical care patients. We were able to identify the major sources ("value chain") of critical care patients: the emergency room, patients who are admitted for other problems but spend time in a critical care unit, and patients transferred to our intensive care units from other hospitals. The greatest opportunity to expand the product line comes from increasing the referrals from other hospitals. A methodology was developed to identify the revenue and expenses associated with critical care, based on the analysis of past experience. With this model, we were able to demonstrate a positive contribution margin of dollar 7 million per year related to patients transferred to the institution primarily for critical care services. This can be seen as the profit related to the product line segment of critical care. There was an additional positive contribution margin of dollar 5.8 million attributed to the critical care portion of the hospital stay of patients admitted primarily through other product lines or the emergency room. This can be seen as the profit related to the "hospital service" segment of critical care. This represented a total contribution margin of dollar 12.8 million, approximately 24% of the institution's entire contribution margin. This information was subsequently used to develop strategic plans to promote this product line. We were able to define the critical care product line, and we were able to demonstrate profitability through an analysis of revenue and expenses related to critical care services. Our experience suggests that the concept of critical care as a product line, in addition to a hospital service, may lead to a useful analysis of this new discipline. This plan provided a rational foundation for development of the operating and capital budgets for the health system.

The effect of interstellar absorption on measurements of the baryon acoustic peak in the Lyman α forest

DOE PAGES

Vadai, Yishay; Poznanski, Dovi; Baron, Dalya; ...

2017-08-14

In recent years, the autocorrelation of the hydrogen Lyman α forest has been used to observe the baryon acoustic peak at redshift 2 < z < 3.5 using tens of thousands of QSO spectra from the BOSS survey. However, the interstellar medium of the Milky Way introduces absorption lines into the spectrum of any extragalactic source. These lines, while weak and undetectable in a single BOSS spectrum, could potentially bias the cosmological signal. In order to examine this, we generate absorption line maps by stacking over a million spectra of galaxies and QSOs. Here, we find that the systematics introducedmore » are too small to affect the current accuracy of the baryon acoustic peak, but might be relevant to future surveys such as the Dark Energy Spectroscopic Instrument (DESI). We outline a method to account for this with future data sets.« less

The effect of interstellar absorption on measurements of the baryon acoustic peak in the Lyman α forest

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vadai, Yishay; Poznanski, Dovi; Baron, Dalya

In recent years, the autocorrelation of the hydrogen Lyman α forest has been used to observe the baryon acoustic peak at redshift 2 < z < 3.5 using tens of thousands of QSO spectra from the BOSS survey. However, the interstellar medium of the Milky Way introduces absorption lines into the spectrum of any extragalactic source. These lines, while weak and undetectable in a single BOSS spectrum, could potentially bias the cosmological signal. In order to examine this, we generate absorption line maps by stacking over a million spectra of galaxies and QSOs. Here, we find that the systematics introducedmore » are too small to affect the current accuracy of the baryon acoustic peak, but might be relevant to future surveys such as the Dark Energy Spectroscopic Instrument (DESI). We outline a method to account for this with future data sets.« less

Stark cell optoacoustic detection of constituent gases in sample

NASA Technical Reports Server (NTRS)

Margolis, J. S.; Shumate, M. S. (Inventor)

1980-01-01

An optoacoustic detector for gas analysis is implemented with Stark effect cell modulation for switching a beam in and out of coincidence with a spectral line of a constituent gas in order to eliminate the heating effect of laser energy in the cell as a source of background noise. By using a multiline laser, and linearly sweeping the DC bias voltage while exciting the cell with a multiline laser, it is possible to obtain a spectrum from which to determine the combinations of excited constituents and determine their concentrations in parts per million.

Analysis of magnesium XI line profiles from solar active regions

NASA Technical Reports Server (NTRS)

Blake, R. L.; Cowan, R. D.; Felthauser, H.; Fenimore, E. E.; Hockaday, M. P.; Bely-Dubau, F.; Faucher, P.; Steenman-Clark, L.

1984-01-01

High-resolution solar spectra of the Mg XI 1s2 1S0-1s2p 1P1 resonance line at 9.169 A and the associated nearby satellite lines obtained from two rocket-borne crystal spectrometer measurements are presented. Comparisons with two independent sets of theoretical calculations for the 1s2nl-1s2pnl dielectronic satellite lines with n = 3-7 indicate electron temperatures of 4-4.5 million K. Measured line widths indicate either that the ion temperature exceeds the electron temperature by about a million K or that about 28 km/s of turbulence is present.

Soft X-ray observations of pre-main sequence stars in the chamaeleon dark cloud

NASA Technical Reports Server (NTRS)

Feigelson, Eric D.; Kriss, Gerard A.

1987-01-01

Einstein IPC observations of the nearby Chamaeleon I star forming cloud show 22 well-resolved soft X-ray sources in a 1x2 deg region. Twelve are associated with H-alpha emission line pre-main sequence (PMS) stars, and four with optically selected PMS stars. Several X-ray sources have two or more PMS stars in their error circles. Optical spectra were obtained at CTIO of possible stellar counterparts of the remaining X-ray sources. They reveal 5 probable new cloud members, K7-MO stars with weak or absent emission lines. These naked X-ray selected PMS stars are similar to those found in the Taurus-Auriga cloud. The spatial distributions and H-R diagrams of the X-ray and optically selected PMS stars in the cloud are very similar. Luminosity functions indicate the Chamaeleon stars are on average approximately 5 times more X-ray luminous than Pleiad dwarfs. A significant correlation between L sub x and optical magnitude suggests this trend may continue within the PMS phase of stellar evolution. The relation of increasing X-ray luminosity with decreasing stellar ages is thus extended to stellar ages as young as 1 million years.

Alu expression in human cell lines and their retrotranspositional potential.

PubMed

Oler, Andrew J; Traina-Dorge, Stephen; Derbes, Rebecca S; Canella, Donatella; Cairns, Brad R; Roy-Engel, Astrid M

2012-06-20

The vast majority of the 1.1 million Alu elements are retrotranspositionally inactive, where only a few loci referred to as 'source elements' can generate new Alu insertions. The first step in identifying the active Alu sources is to determine the loci transcribed by RNA polymerase III (pol III). Previous genome-wide analyses from normal and transformed cell lines identified multiple Alu loci occupied by pol III factors, making them candidate source elements. Analysis of the data from these genome-wide studies determined that the majority of pol III-bound Alus belonged to the older subfamilies Alu S and Alu J, which varied between cell lines from 62.5% to 98.7% of the identified loci. The pol III-bound Alus were further scored for estimated retrotransposition potential (ERP) based on the absence or presence of selected sequence features associated with Alu retrotransposition capability. Our analyses indicate that most of the pol III-bound Alu loci candidates identified lack the sequence characteristics important for retrotransposition. These data suggest that Alu expression likely varies by cell type, growth conditions and transformation state. This variation could extend to where the same cell lines in different laboratories present different Alu expression patterns. The vast majority of Alu loci potentially transcribed by RNA pol III lack important sequence features for retrotransposition and the majority of potentially active Alu loci in the genome (scored high ERP) belong to young Alu subfamilies. Our observations suggest that in an in vivo scenario, the contribution of Alu activity on somatic genetic damage may significantly vary between individuals and tissues.

Massive Gas Cloud Around Jupiter

NASA Technical Reports Server (NTRS)

2003-01-01

An innovative instrument on NASA's Cassini spacecraft makes the space environment around Jupiter visible, revealing a donut-shaped gas cloud encircling the planet.

The image was taken with the energetic neutral atom imaging technique by the Magnetospheric Imaging Instrument on Cassini as the spacecraft flew past Jupiter in early 2001 at a distance of about 10 million kilometers (6 million miles). This technique provides information about a source by detecting neutral atoms emitted by the source, comparable to how a camera reveals information about an object by detecting photons coming from the object.

The central object in this image represents energetic neutral atom emissions from Jupiter itself. The outer two objects represent emissions from a donut-shaped cloud, or torus, that shares an orbit with Jupiter's moon Europa. The cloud's emissions appear dot-like because of the viewing angle. The torus is viewed edge-on, and the image is brightest at the line-of-sight angles that pass through the greatest volume of it.

Cassini is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. The Jet Propulsion Laboratory, a division of the California Institute of Technology in Pasadena, Calif., manages Cassini for NASA's Office of Space Science, Washington, D.C.

NASA Scientific and Technical Information System (STI) and New Directory of Numerical Data Bases

NASA Technical Reports Server (NTRS)

Wilson, J.

1984-01-01

The heart of NASA's STI system is a collection of scientific and technical information gathered from worldwide sources. Currently containing over 2.2 million items, the data base is growing at the rate of 140,000 items per year. In addition to announcement journals, information is disseminated through the NASA RECON on-line bibliographic search system. One part of RECON is NALNET which lists journals and books held by the NASA Centers. Another service now accessible by recon is a directory of numerical data bases (DND) which can be shared by NASA staff and contractors. The DND describes each data base and gives the name and phone number of a contact person. A NASA-wide integrated library system is being developed for the Center libraries which will include on-line catalog and subsystems for acquisition, circulation control, information retrieveal, management information, and an authority file. These subsystems can interact with on-line bibliographic, patron, and vendor files.

From the Sun with Love

NASA Image and Video Library

2017-12-08

This Solar Dynamics Observatory (SDO) image of the Sun taken on January 20, 2012 in extreme ultraviolet light captures a heart-shaped dark coronal hole. Coronal holes are areas of the Sun's surface that are the source of open magnetic field lines that head way out into space. They are also the source regions of the fast solar wind, which is characterized by a relatively steady speed of approximately 800 km/s (about 1.8 million mph). NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Multi-MHz FDML OCT: snapshot retinal imaging at 6.7 million axial-scans per second

NASA Astrophysics Data System (ADS)

Klein, Thomas; Wieser, Wolfgang; André, Raphael; Pfeiffer, Tom; Eigenwillig, Christoph M.; Huber, Robert

2012-01-01

We demonstrate the acquisition of densely sampled wide-field 3D OCT datasets of the human retina in 0.3s. This performance is achieved with a multi-MHz Fourier domain mode-locked (FDML) laser source operating at 1050nm. A two-beam setup doubles the 3.35MHz laser sweep rate to 6.7MHz, which is 16x faster than results achieved with any non-FDML source used for retinal OCT. We discuss two main benefits of these high line rates: First, large datasets over an ultra-wide field of view can be acquired with a low probability of distortions. Second, even if eye movements occur, now the scan rate is high enough to directly correct even the fastest saccades without loss of information.

The Global Drug Facility as an intervention in the market for tuberculosis drugs

PubMed Central

Cordier-Lassalle, Thierry; Lunte, Kaspars; Dye, Christopher

2015-01-01

Abstract Objective To investigate funding for the Global Drug Facility since 2001 and to analyse the facility’s influence on the price of high-quality tuberculosis drugs. Methods Data on the price of tuberculosis drugs were obtained from the Global Drug Facility for 2001 to 2012 and, for the private sector in 15 countries, from IMS Health for 2002 to 2012. Data on funding of the facility were also collected. Findings Quality-assured tuberculosis drugs supplied by the Global Drug Facility were generally priced lower than drugs purchased in the private sector. In 2012, just three manufacturers accounted for 29.9 million United Stated dollars (US$) of US$ 44.5 million by value of first-line drugs supplied. The Global Fund to Fight AIDS, Tuberculosis and Malaria provided 73% (US$ 32.5 million of US$ 44.5 million) and 89% (US$ 57.8 million of US $65.2 million) of funds for first- and second-line drugs, respectively. Between 2010 and 2012, the facility’s market share of second-line tuberculosis drugs increased from 26.1% to 42.9%, while prices decreased by as much as 24% (from US$ 1231 to US$ 939). Conversely, the facility’s market share of first-line drugs fell from 37.2% to 19.2% during this time, while prices increased from US$ 9.53 to US$ 10.2. Conclusion The price of tuberculosis drugs supplied through the facility was generally less than that on the private market. However, to realize its full potential and meet the needs of more tuberculosis patients, the facility requires more diverse and stable public funding and greater flexibility to participate in the private market. PMID:26229188

The Global Drug Facility as an intervention in the market for tuberculosis drugs.

PubMed

Arinaminpathy, Nimalan; Cordier-Lassalle, Thierry; Lunte, Kaspars; Dye, Christopher

2015-04-01

To investigate funding for the Global Drug Facility since 2001 and to analyse the facility's influence on the price of high-quality tuberculosis drugs. Data on the price of tuberculosis drugs were obtained from the Global Drug Facility for 2001 to 2012 and, for the private sector in 15 countries, from IMS Health for 2002 to 2012. Data on funding of the facility were also collected. Quality-assured tuberculosis drugs supplied by the Global Drug Facility were generally priced lower than drugs purchased in the private sector. In 2012, just three manufacturers accounted for 29.9 million United Stated dollars (US$) of US$ 44.5 million by value of first-line drugs supplied. The Global Fund to Fight AIDS, Tuberculosis and Malaria provided 73% (US$ 32.5 million of US$ 44.5 million) and 89% (US$ 57.8 million of US $65.2 million) of funds for first- and second-line drugs, respectively. Between 2010 and 2012, the facility's market share of second-line tuberculosis drugs increased from 26.1% to 42.9%, while prices decreased by as much as 24% (from US$ 1231 to US$ 939). Conversely, the facility's market share of first-line drugs fell from 37.2% to 19.2% during this time, while prices increased from US$ 9.53 to US$ 10.2. The price of tuberculosis drugs supplied through the facility was generally less than that on the private market. However, to realize its full potential and meet the needs of more tuberculosis patients, the facility requires more diverse and stable public funding and greater flexibility to participate in the private market.

Estimated withdrawals and use of freshwater in New Hampshire, 1990

USGS Publications Warehouse

Medalie, Laura; Horn, M.A.

1994-01-01

Estimated freshwater withdrawals during 1990 in New Hampshire totaled about 422 million gallons per day from ground-water and surface-water sources. The largest withdrawals were for thermoelectric-power generation (60 percent), public supply (23 percent), and industrial use (9 percent). Most withdrawals, 358 million gallons per day, were made from surface- water sources, as compared to 63.7 million gallons per day from ground-water sources. The largest with- drawals were in the Merrimack river basin (322 million gallons per day). An additional 46,000 million gallons per day was used instream for hydroelectric-power generation, primarily in the Upper Androscoggin and Upper Connecticut River subbasins. Other information describing water-use patterns is shown in tables, bar graphs, pie charts, maps, and accompanying text. The data are aggregated by river basin (hydrologic cataloging unit), and all values are reported in million gallons per day.

QUASI-STAR JETS AS UNIDENTIFIED GAMMA-RAY SOURCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Czerny, Bozena; Sikora, Marek; Janiuk, Agnieszka

2012-08-10

Gamma-ray catalogs contain a considerable amount of unidentified sources. Many of these are located out of the Galactic plane and therefore may have extragalactic origin. Here we assume that the formation of massive black holes in galactic nuclei proceeds through a quasi-star stage and consider the possibility of jet production by such objects. Those jets would be the sources of collimated synchrotron and Compton emission, extending from radio to gamma rays. The expected lifetimes of quasi-stars are of the order of million of years while the jet luminosities, somewhat smaller than that of quasar jets, are sufficient to account formore » the unidentified gamma-ray sources. The jet emission dominates over the thermal emission of a quasi-star in all energy bands, except when the jet is not directed toward an observer. The predicted synchrotron emission peaks in the IR band, with the flux close to the limits of the available IR all sky surveys. The ratio of the gamma-ray flux to the IR flux is found to be very large ({approx}60), much larger than in BL Lac objects but reached by some radio-loud quasars. On the other hand, radio-loud quasars show broad emission lines while no such lines are expected from quasi-stars. Therefore, the differentiation between various scenarios accounting for the unidentified gamma-ray sources will be possible at the basis of the photometry and spectroscopy of the IR/optical counterparts.« less

JPRS Report, Soviet Union, Foreign Military Review, No. 8, August 1987

DTIC Science & Technology

1988-01-28

Hinkley Point (1.5 million) and Hartlepool (1.3 million). In recent years the country has begun building large hydro- electric pumped storage power ...antenna 6. Interface equipment 7. Data transmission line terminal 8. Computer 9. Power supply plant control station 10. Radio-relay station terminals... stations and data transmission line, interface equipment, and power distribution unit (Fig. 3). The parallel computer, which performs operations on

SDSS-IV MaNGA: the spectroscopic discovery of strongly lensed galaxies

NASA Astrophysics Data System (ADS)

Talbot, Michael S.; Brownstein, Joel R.; Bolton, Adam S.; Bundy, Kevin; Andrews, Brett H.; Cherinka, Brian; Collett, Thomas E.; More, Anupreeta; More, Surhud; Sonnenfeld, Alessandro; Vegetti, Simona; Wake, David A.; Weijmans, Anne-Marie; Westfall, Kyle B.

2018-06-01

We present a catalogue of 38 spectroscopically detected strong galaxy-galaxy gravitational lens candidates identified in the Sloan Digital Sky Survey IV (SDSS-IV). We were able to simulate narrow-band images for eight of them demonstrating evidence of multiple images. Two of our systems are compound lens candidates, each with two background source-planes. One of these compound systems shows clear lensing features in the narrow-band image. Our sample is based on 2812 galaxies observed by the Mapping Nearby Galaxies at APO (MaNGA) integral field unit (IFU). This Spectroscopic Identification of Lensing Objects (SILO) survey extends the methodology of the Sloan Lens ACS Survey (SLACS) and BOSS Emission-Line Survey (BELLS) to lower redshift and multiple IFU spectra. We searched ˜1.5 million spectra, of which 3065 contained multiple high signal-to-noise ratio background emission-lines or a resolved [O II] doublet, that are included in this catalogue. Upon manual inspection, we discovered regions with multiple spectra containing background emission-lines at the same redshift, providing evidence of a common source-plane geometry which was not possible in previous SLACS and BELLS discovery programs. We estimate more than half of our candidates have an Einstein radius ≳ 1.7 arcsec, which is significantly greater than seen in SLACS and BELLS. These larger Einstein radii produce more extended images of the background galaxy increasing the probability that a background emission-line will enter one of the IFU spectroscopic fibres, making detection more likely.

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri.

PubMed

Bashyal, Bharat; Li, Linfeng; Bains, Trpta; Debnath, Anjan; LaBarbera, Daniel V

2017-08-01

Protozoan parasites infect and kill millions of people worldwide every year, particularly in developing countries where access to clean fresh water is limited. Among the most common are intestinal parasites, including Giardia lamblia and Entamoeba histolytica. These parasites wreak havoc on the epithelium lining the small intestines (G. lamblia) and colon (E. histolytica) causing giardiasis and amebiasis, respectively. In addition, there are less common but far more deadly pathogens such as Naegleria fowleri that thrive in warm waters and infect the central nervous systems of their victims via the nasal passages. Despite their prevalence and associated high mortality rates, there remains an unmet need to identify more effective therapeutics for people infected with these opportunistic parasites. To address this unmet need, we have surveyed plants and traditional herbal medicines known throughout the world to identify novel antiparasitic agents with activity against G. lamblia, E. histolytica, and N. fowleri. Herein, we report Larrea tridentata, known as creosote bush, as a novel source for secondary metabolites that display antiparasitic activity against all three pathogens. This report also characterizes the lignan compound classes, nordihydroguairetic acid and demethoxyisoguaiacin, as novel antiparasitic lead agents to further develop more effective drug therapy options for millions of people worldwide.

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri

PubMed Central

Bains, Trpta; Debnath, Anjan

2017-01-01

Protozoan parasites infect and kill millions of people worldwide every year, particularly in developing countries where access to clean fresh water is limited. Among the most common are intestinal parasites, including Giardia lamblia and Entamoeba histolytica. These parasites wreak havoc on the epithelium lining the small intestines (G. lamblia) and colon (E. histolytica) causing giardiasis and amebiasis, respectively. In addition, there are less common but far more deadly pathogens such as Naegleria fowleri that thrive in warm waters and infect the central nervous systems of their victims via the nasal passages. Despite their prevalence and associated high mortality rates, there remains an unmet need to identify more effective therapeutics for people infected with these opportunistic parasites. To address this unmet need, we have surveyed plants and traditional herbal medicines known throughout the world to identify novel antiparasitic agents with activity against G. lamblia, E. histolytica, and N. fowleri. Herein, we report Larrea tridentata, known as creosote bush, as a novel source for secondary metabolites that display antiparasitic activity against all three pathogens. This report also characterizes the lignan compound classes, nordihydroguairetic acid and demethoxyisoguaiacin, as novel antiparasitic lead agents to further develop more effective drug therapy options for millions of people worldwide. PMID:28793307

SELFI: an object-based, Bayesian method for faint emission line source detection in MUSE deep field data cubes

NASA Astrophysics Data System (ADS)

Meillier, Céline; Chatelain, Florent; Michel, Olivier; Bacon, Roland; Piqueras, Laure; Bacher, Raphael; Ayasso, Hacheme

2016-04-01

We present SELFI, the Source Emission Line FInder, a new Bayesian method optimized for detection of faint galaxies in Multi Unit Spectroscopic Explorer (MUSE) deep fields. MUSE is the new panoramic integral field spectrograph at the Very Large Telescope (VLT) that has unique capabilities for spectroscopic investigation of the deep sky. It has provided data cubes with 324 million voxels over a single 1 arcmin2 field of view. To address the challenge of faint-galaxy detection in these large data cubes, we developed a new method that processes 3D data either for modeling or for estimation and extraction of source configurations. This object-based approach yields a natural sparse representation of the sources in massive data fields, such as MUSE data cubes. In the Bayesian framework, the parameters that describe the observed sources are considered random variables. The Bayesian model leads to a general and robust algorithm where the parameters are estimated in a fully data-driven way. This detection algorithm was applied to the MUSE observation of Hubble Deep Field-South. With 27 h total integration time, these observations provide a catalog of 189 sources of various categories and with secured redshift. The algorithm retrieved 91% of the galaxies with only 9% false detection. This method also allowed the discovery of three new Lyα emitters and one [OII] emitter, all without any Hubble Space Telescope counterpart. We analyzed the reasons for failure for some targets, and found that the most important limitation of the method is when faint sources are located in the vicinity of bright spatially resolved galaxies that cannot be approximated by the Sérsic elliptical profile. The software and its documentation are available on the MUSE science web service (muse-vlt.eu/science).

Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis.

PubMed

Schweitzer, Mary H; Zheng, Wenxia; Organ, Chris L; Avci, Recep; Suo, Zhiyong; Freimark, Lisa M; Lebleu, Valerie S; Duncan, Michael B; Vander Heiden, Matthew G; Neveu, John M; Lane, William S; Cottrell, John S; Horner, John R; Cantley, Lewis C; Kalluri, Raghu; Asara, John M

2009-05-01

Molecular preservation in non-avian dinosaurs is controversial. We present multiple lines of evidence that endogenous proteinaceous material is preserved in bone fragments and soft tissues from an 80-million-year-old Campanian hadrosaur, Brachylophosaurus canadensis [Museum of the Rockies (MOR) 2598]. Microstructural and immunological data are consistent with preservation of multiple bone matrix and vessel proteins, and phylogenetic analyses of Brachylophosaurus collagen sequenced by mass spectrometry robustly support the bird-dinosaur clade, consistent with an endogenous source for these collagen peptides. These data complement earlier results from Tyrannosaurus rex (MOR 1125) and confirm that molecular preservation in Cretaceous dinosaurs is not a unique event.

High-resolution VLBA imaging of the radio source Sgr A* at the Galactic Centre

NASA Technical Reports Server (NTRS)

Lo, K. Y.; Backer, D. C.; Kellermann, K. I.; Reid, M.; Zhao, J. H.; Goss, W. M.; Moran, J. M.

1993-01-01

Images of Sgr* A with milliarcsecond resolution obtained by using five telescopes of the partially completed Very Long Baseline Array (VLBA) in conjunction with a few additional telescopes are presented. The image of Sgr A* at a wavelength of 3.6 cm confirms almost exactly the elliptical Gaussian model that has been proposed on the basis of previous data. The source size at 1.34 cm wavelength is 2.4 +/- 0.2 mas, similar to previous results. At both wavelengths, the radio source is smooth, without detectable fine structure. These observations support the suggestion that the radio emission from Sgr A* is strongly scattered by electron-density fluctuations along the line of sight. On the assumption that the emission is due to a black hole accreting stellar winds from massive stars in the central 0.5 pc, the observations are consistent with a black hole mass of less than about 2 million solar masses.

SESAME, A 3rd Generation Synchrotron Light Source for the Middle East

DOE Office of Scientific and Technical Information (OSTI.GOV)

Einfeld, D.; Hasnain, S.S.; Sayers, Z.

2004-05-12

Developed under the auspices of UNESCO, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) will be a major international research centre in the Middle East and Mediterranean region. On 6th of January 2003, the official foundation of SESAME took place. The facility is located in Allan, Jordan, 30 km North-West of Amman. As of August 2003 the Founding Members are Bahrain, Egypt, Iran, Israel, Jordan, Pakistan, Palestine, Turkey and United Arabic Emirates, representing a population of over 300 million. SESAME will be a 2.5 GeV 3rd Generation light source (emittance 24.6 nm.rad, circumference {approx}125m). About 40% ofmore » the circumference is available for insertion devices (average length 2.75m) in 13 straight sections. Beam lines are up to 36m. The site and a building are provided by Jordan. Construction started in August 2003. The scientific program will start with up to 6 beam lines: MAD Protein Crystallography, SAXS and WAXS for polymers and proteins, Powder Diffraction for material science, UV/VUV/SXR Photoelectron Spectroscopy and Photoabsorption Spectroscopy, IR Spectroscopy, and EXAFS.« less

How to review 4 million lines of ATLAS code

NASA Astrophysics Data System (ADS)

Stewart, Graeme A.; Lampl, Walter; ATLAS Collaboration

2017-10-01

As the ATLAS Experiment prepares to move to a multi-threaded framework (AthenaMT) for Run3, we are faced with the problem of how to migrate 4 million lines of C++ source code. This code has been written over the past 15 years and has often been adapted, re-written or extended to the changing requirements and circumstances of LHC data taking. The code was developed by different authors, many of whom are no longer active, and under the deep assumption that processing ATLAS data would be done in a serial fashion. In order to understand the scale of the problem faced by the ATLAS software community, and to plan appropriately the significant efforts posed by the new AthenaMT framework, ATLAS embarked on a wide ranging review of our offline code, covering all areas of activity: event generation, simulation, trigger, reconstruction. We discuss the difficulties in even logistically organising such reviews in an already busy community, how to examine areas in sufficient depth to learn key areas in need of upgrade, yet also to finish the reviews in a timely fashion. We show how the reviews were organised and how the ouptuts were captured in a way that the sub-system communities could then tackle the problems uncovered on a realistic timeline. Further, we discuss how the review has inuenced the overall planning for the Run 3 ATLAS offline code.

Widespread Amazon forest tree mortality from a single cross-basin squall line event

NASA Astrophysics Data System (ADS)

Negrón-Juárez, Robinson I.; Chambers, Jeffrey Q.; Guimaraes, Giuliano; Zeng, Hongcheng; Raupp, Carlos F. M.; Marra, Daniel M.; Ribeiro, Gabriel H. P. M.; Saatchi, Sassan S.; Nelson, Bruce W.; Higuchi, Niro

2010-08-01

Climate change is expected to increase the intensity of extreme precipitation events in Amazonia that in turn might produce more forest blowdowns associated with convective storms. Yet quantitative tree mortality associated with convective storms has never been reported across Amazonia, representing an important additional source of carbon to the atmosphere. Here we demonstrate that a single squall line (aligned cluster of convective storm cells) propagating across Amazonia in January, 2005, caused widespread forest tree mortality and may have contributed to the elevated mortality observed that year. Forest plot data demonstrated that the same year represented the second highest mortality rate over a 15-year annual monitoring interval. Over the Manaus region, disturbed forest patches generated by the squall followed a power-law distribution (scaling exponent α = 1.48) and produced a mortality of 0.3-0.5 million trees, equivalent to 30% of the observed annual deforestation reported in 2005 over the same area. Basin-wide, potential tree mortality from this one event was estimated at 542 ± 121 million trees, equivalent to 23% of the mean annual biomass accumulation estimated for these forests. Our results highlight the vulnerability of Amazon trees to wind-driven mortality associated with convective storms. Storm intensity is expected to increase with a warming climate, which would result in additional tree mortality and carbon release to the atmosphere, with the potential to further warm the climate system.

Poverty and Brain Development During Childhood: An Approach from Cognitive Psychology and Neuroscience. Human Brain Development Series

ERIC Educational Resources Information Center

Lipina, Sebastian J.; Colombo, Jorge A.

2009-01-01

Poverty remains an urgent crisis worldwide. In the United States, 28.6 million children live in low-income families and 12.7 million children live in poor families. In nations belonging to the Organization for Economic Co-operation and Development (OECD), 47 million children live below national poverty lines. These figures pertain to…

Overview of Hydrometeorologic Forecasting Procedures at BC Hydro

NASA Astrophysics Data System (ADS)

McCollor, D.

2004-12-01

Energy utility companies must balance production from limited sources with increasing demand from industrial, business, and residential consumers. The utility planning process requires a balanced, efficient, and effective distribution of energy from source to consumer. Therefore utility planners must consider the impact of weather on energy production and consumption. Hydro-electric companies should be particularly tuned to weather because their source of energy is water, and water supply depends on precipitation. BC Hydro operates as the largest hydro-electric company in western Canada, managing over 30 reservoirs within the province of British Columbia, and generating electricity for 1.6 million people. BC Hydro relies on weather forecasts of watershed precipitation and temperature to drive hydrologic reservoir inflow models and of urban temperatures to meet energy demand requirements. Operations and planning specialists in the company rely on current, value-added weather forecasts for extreme high-inflow events, daily reservoir operations planning, and long-term water resource management. Weather plays a dominant role for BC Hydro financial planners in terms of sensitive economic responses. For example, a two percent change in hydropower generation, due in large part to annual precipitation patterns, results in an annual net change of \\50 million in earnings. A five percent change in temperature produces a \\5 million change in yearly earnings. On a daily basis, significant precipitation events or temperature extremes involve potential profit/loss decisions in the tens of thousands of dollars worth of power generation. These factors are in addition to environmental and societal costs that must be considered equally as part of a triple bottom line reporting structure. BC Hydro water resource managers require improved meteorological information from recent advancements in numerical weather prediction. At BC Hydro, methods of providing meteorological forecast data are changing as new downscaling and ensemble techniques evolve to improve environmental information supplied to water managers.

Assessing the Financial Benefits of Faster Development Times: The Case of Single-source Versus Multi-vendor Outsourced Biopharmaceutical Manufacturing.

PubMed

DiMasi, Joseph A; Smith, Zachary; Getz, Kenneth A

2018-05-10

The extent to which new drug developers can benefit financially from shorter development times has implications for development efficiency and innovation incentives. We provided a real-world example of such gains by using recent estimates of drug development costs and returns. Time and fee data were obtained on 5 single-source manufacturing projects. Time and fees were modeled for these projects as if the drug substance and drug product processes had been contracted separately from 2 vendors. The multi-vendor model was taken as the base case, and financial impacts from single-source contracting were determined relative to the base case. The mean and median after-tax financial benefits of shorter development times from single-source contracting were $44.7 million and $34.9 million, respectively (2016 dollars). The after-tax increases in sponsor fees from single-source contracting were small in comparison (mean and median of $0.65 million and $0.25 million). For the data we examined, single-source contracting yielded substantial financial benefits over multi-source contracting, even after accounting for somewhat higher sponsor fees. Copyright © 2018 Elsevier HS Journals, Inc. All rights reserved.

Potential industrial sites in the Lynn Canal area, Alaska

USGS Publications Warehouse

Johnson, Arthur; Twenhofel, William Stephens

1953-01-01

Full development of a proposal to divert the headwaters of the Yukon River drainage from Canada into the Taiya River valley of Alaska would make available more than a half million kilowatts of electrical energy. Utilization of this block of power, for which there is at present no local market, will require an industrial and community development of appreciable magnitude. Suitable sites for industrial and community development near the proposed power source are limited because of the extremely rugged and mountainous terrain of the Lynn Canal area. This report considers potential industrial areas at Skagway, Taiya River, Ferebee River, Lutak Inlet, Haines and vicinity, Klukwan and vicinity, Haines to Klukwan along the Haines cutoff, Berners Bay, and Juneau and vicinity. The factors considered in their evaluation are topography, geology, climate, water supply, transportation facilities, and transmission-line routes from the source of power.

The VIRUS Emission Line Detection Recipe

NASA Astrophysics Data System (ADS)

Gössl, C. A.; Hopp, U.; Köhler, R.; Grupp, F.; Relke, H.; Drory, N.; Gebhardt, K.; Hill, G.; MacQueen, P.

2007-10-01

HETDEX, the Hobby-Eberly Telescope Dark Energy Experiment, will measure the imprint of the baryonic acoustic oscillations on the galaxy population at redshifts of 1.8 < z < 3.7 to constrain the nature of dark energy. The survey will be performed over at least 200 deg^2. The tracer population for this blind search will be Ly-α emitting galaxies through their most prominent emission line. The data reduction pipeline will extract these emission line objects from ˜35,000 spectra per exposure (5 million per night, i.e. 500 million in total) while performing astrometric, photometric, and wavelength calibration fully automatically. Here we will present our ideas how to find and classify objects even at low signal-to-noise ratios.

Reconnaissance geology and geochronology of the Precambrian of the Granite Mountains, Wyoming

USGS Publications Warehouse

Peterman, Zell E.; Hildreth, Robert A.

1978-01-01

The Precambrian of the western part of the Granite Mountains, Wyoming, contains a metamorphic complex of gneisses, schists, and amphibolites that were derived through amphibolite-grade metamorphism from a sedimentary-volcanic sequence perhaps similar to that exposed in the southeastern Wind River Mountains. Whole-rock Rb-Sr dating places the time of metamorphism at 2,860?80 million years. A high initial 87Sr/ 86 S r ratio of 0.7048 suggests that either the protoliths or the source terrane of the sedimentary component is several hundred million years older than the time of metamorphism. Following an interval of 300:t100 million years for which the geologic record is lacking or still undeciphered, the metamorphic complex was intruded by a batholith and satellite bodies of medium- to coarse-grained, generally massive biotite granite and related pegmatite and aplite. The main body of granite is dated at 2,550?60 million years by the Rb-Sr method. Limited data suggest that diabase dikes were emplaced and nephrite veins were formed only shortly after intrusion of the granite. Emplacement of the granite at about 2,550 million years ago appears to be related to a major period of regional granitic plutonism in the Precambrian of southern and western Wyoming. Granites, in the strict sense, that are dated between 2,450 and 2,600 million years occur in the Teton Range, the Sierra Madre, the Medicine Bow Mountains and the Laramie Range. This episode of granitic plutonism occured some 50 to 100 million years later than the major tonalitic to granitic plutonism in the Superior province of northern Minnesota and adjacent Ontario-the nearest exposed Precambrian W terrane that is analogous to the Wyoming province. Initial 87Sr / 86Sr ratios of some of the Wyoming granites are higher than expected if the rocks had been derived from juvenile magmas and it is likely that older crustal rocks were involved to some degree in the generation of these granites. Slightly to highly disturbed Rb-Sr and K-Ar mineral ages are obtained on rocks of the metamorphic complex and on the granite. These ages range from about 2,400 to 1,420 million years and are part of a regional pattern of lowered mineral ages of Precambrian W rocks of southern Wyoming. A major discontinuity in these mineral ages occurs along a line extending from the northern Laramie Range, through the northern part of the Granite Mountains, to the southeastern Wind River Mountains. North of this line, Rb-Sr and K-Ar biotite ages are 2,300 million years or greater, whereas to the south, the biotite ages decrease drastically over a short distance, to a common range of 1,600-1,400 million years. We suggest that these lowered ages represent regional cooling below the 300 0 C isotherm as a consequence of uplift and erosion of the large crustal block occurring south of the age discontinuity. In this interpretation, the westerly-trending age discontinuity would be a zone of major crustal dislocation that resulted from vertical tectonics in late Precambrian X or early Precambrian Y time.

Estimated withdrawals and use of freshwater in Vermont, 1990

USGS Publications Warehouse

Horn, M.A.; Medalie, Laura

1996-01-01

Estimated freshwater withdrawals during 1990 in Vermont totaled about 632 million gallons per day. The largest withdrawals were for thermoelectric- power generation (82 percent), industrial use (7 percent), and public supply (6 percent). Most withdrawals, 587 million gallons per day, were made from surface-water sources as compared to 44.9 million gallons per day from ground-water sources. The largest withdrawals were in the Upper Connecticut-Mascomo River Basin (525 million gallons per day). About 17,700 million gallons per day were used instream for hydroelectric-poser generation, the largest of which were in the Upper Connecticut-Mascoma and Otter River Basins. Other information describing water-use patters is shown in tables, bar graphs, pie charts, maps, and accompanying text. The data are aggregated by river basin (hydrologic cataloging unit), and all amounts are reports in million gallons per day.

Accretion tori and cones of ionizing radiation in Seyfert galaxies

NASA Technical Reports Server (NTRS)

Acosta-Pulido, Jose A.; Perez-Fournon, Ismael; Calvani, Massimo; Wilson, Andrew S.

1990-01-01

The photoionization of extended narrow-line regions in Seyfert galaxies by the radiation produced in a thick accretion disk is studied. The emission-line spectrum is calculated for a range of black hole masses, varying the values of the ionization parameter and the disk size. It is found that models with a million solar masses fit observations of very large accretion disk sizes, while models with 10 million solar masses fit them better with smaller disks. The latter models are preferable since they have lower super-Eddington accretion rates.

27 CFR 9.90 - Willamette Valley.

Code of Federal Regulations, 2012 CFR

2012-04-01

... east by the Cascade Mountains, encompassing approximately 5,200 square miles (3.3 million acres). The... miles to its intersection with the Washington/Multnomah County line; (2) South along the Washington County line 5 miles to its intersection with the 1,000 foot contour line; (3) Northwest (15 miles due...

27 CFR 9.90 - Willamette Valley.

Code of Federal Regulations, 2013 CFR

2013-04-01

... east by the Cascade Mountains, encompassing approximately 5,200 square miles (3.3 million acres). The... miles to its intersection with the Washington/Multnomah County line; (2) South along the Washington County line 5 miles to its intersection with the 1,000 foot contour line; (3) Northwest (15 miles due...

27 CFR 9.90 - Willamette Valley.

Code of Federal Regulations, 2014 CFR

2014-04-01

... east by the Cascade Mountains, encompassing approximately 5,200 square miles (3.3 million acres). The... miles to its intersection with the Washington/Multnomah County line; (2) South along the Washington County line 5 miles to its intersection with the 1,000 foot contour line; (3) Northwest (15 miles due...

21 CFR 179.21 - Sources of radiation used for inspection of food, for inspection of packaged food, and for...

Code of Federal Regulations, 2013 CFR

2013-04-01

... radiations at energy levels of not more than 2.2 million electron volts from one of the following isotopes... in food. (4) Machine sources producing X-radiation at energies no greater than 10 million electron...

21 CFR 179.21 - Sources of radiation used for inspection of food, for inspection of packaged food, and for...

Code of Federal Regulations, 2012 CFR

2012-04-01

... radiations at energy levels of not more than 2.2 million electron volts from one of the following isotopes... in food. (4) Machine sources producing X-radiation at energies no greater than 10 million electron...

21 CFR 179.21 - Sources of radiation used for inspection of food, for inspection of packaged food, and for...

Code of Federal Regulations, 2011 CFR

2011-04-01

... radiations at energy levels of not more than 2.2 million electron volts from one of the following isotopes... in food. (4) Machine sources producing X-radiation at energies no greater than 10 million electron...

High-sensitivity supercontinuum-based parallel line-field optical coherence tomography with 1 million A-lines/s (Conference Presentation)

NASA Astrophysics Data System (ADS)

Barrick, Jessica; Doblas, Ana; Sears, Patrick R.; Ostrowski, Lawrence E.; Oldenburg, Amy L.

2017-02-01

While traditional, flying-spot, spectral domain OCT systems can achieve MHz linerates, they are limited by the need for mechanical scanning to produce a B-mode image. Line-field OCT (LF OCT) removes the need for mechanical scanning by simultaneously recording all A-lines on a 2D CMOS sensor. Our LF OCT system operates at the highest A-line rate of any spectral domain (SD) LF OCT system reported to date (1,024,000 A-lines/s). This is comparable with the fastest flying-spot SDOCT system reported. Additionally, all OCT systems face a tradeoff between imaging speed and sensitivity. Long exposure times improve sensitivity but can lead to undesirable motion artifacts. LF OCT has the potential to relax this tradeoff between sensitivity and imaging speed because all A-lines are exposed during the entire frame acquisition time. However, this advantage has not yet been realized due to the loss of power-per-A-line by spreading the illumination light across all A-lines on the sample. Here we use a supercontinuum source to illuminate the sample with 500mW of light in the 605-950 nm wavelength band, effectively providing 480 µW of power-per-A-line, with axial and lateral resolutions of 1.8 µm and 14 µm, respectively. With this system we achieve the highest reported sensitivity (113 dB) of any LF OCT system. We then demonstrate the capability of this system by capturing the rapidly beating cilia of human bronchial-epithelial cells in vitro. The combination of high speed and high sensitivity offered by supercontinuum-based LF SD OCT offers new opportunities for studying cell and tissue dynamics.

A 'Plumefall' on Io

NASA Technical Reports Server (NTRS)

2007-01-01

New Horizons took this image of Jupiter's volcanic moon Io with its Long Range Reconnaissance Imager (LORRI) at 15:15 Universal Time on February 28, 2007, nearly 10 hours after the spacecraft's closest approach to Jupiter. The image is centered at Io coordinates 5 degrees south, 92 degrees west, and the spacecraft was 2.4 million kilometers (1.5 million miles) from Io. Io's diameter is 3,640 kilometers (2,262 miles).

Io's dayside was deliberately overexposed in this image to bring out details on the nightside and in any volcanic plumes that might be present. Io cooperated by producing an enormous plume, 330 kilometers (200 miles) high, from the volcano Tvashtar. Near Io's north pole, Tvashtar was active throughout New Horizons' Jupiter encounter.

In this image, volcanic debris from the plume, illuminated by the setting sun, rains down onto Io's nightside. Hot, glowing lava at the source of the plume is the bright point of light on the sunlit side of the terminator (the line separating day and night). Elsewhere along the terminator, mountains catch the setting sun. The nightside of Io is lit up by light reflected from Jupiter.

Ultraviolet Opacity and Fluorescence in Supernova Envelopes

NASA Technical Reports Server (NTRS)

Li, Hongwei; McCray, Richard

1996-01-01

By the time the expanding envelope of a Type 2 supernova becomes transparent in the optical continuum, most of the gamma-ray luminosity produced by radioactive Fe/Co/Ni clumps propagates into the hydrogen/helium envelope and is deposited there, if at all. The resulting fast electrons excite He 1 and H 1, the two- photon continua of which are the dominant internal sources of ultraviolet radiation. The UV radiation is blocked by scattering in thousands of resonance lines of metals and converted by fluorescence into optical and infrared emission lines that escape freely. We describe results of Monte Carlo calculations that simulate non-LTE scattering and fluorescence in more than five million allowed lines of Ca, Sc, Ti, V, Cr, Mn, Fe, Co, and Ni. For a model approximating conditions in the envelope of SN 1987A, the calculated emergent spectrum resembles the observed one. For the first 2 yr after explosion, the ultraviolet radiation (lambda less than or approximately equals 3000) is largely blocked and converted into a quasi continuum of many thousands of weak optical and infrared emission lines and some prominent emission features, such as the Ca 2 lambdalambda8600 triplet. Later, as the envelope cools and expands, it becomes more transparent, and an increasing fraction of the luminosity emerges in the UV band.

Democracy and Tunisia: A Case Study

DTIC Science & Technology

1994-06-01

2591 E. ISLAMIC MOVEMENT The al-Nahda Islamic movement, originally called the Mouvement de la Tendance Islamique (MTI), is claimed by the government to...billion for the period 1987-1991. At the same time reportedly an African Development Bank offered a $79 million credit line to finance tourism and...industrial projects, England’s Midland Bank financed $27 million and the Italian government provided $500 million in loans and grants for a five year

A Roadmap to Continuous Integration for ATLAS Software Development

NASA Astrophysics Data System (ADS)

Elmsheuser, J.; Krasznahorkay, A.; Obreshkov, E.; Undrus, A.; ATLAS Collaboration

2017-10-01

The ATLAS software infrastructure facilitates efforts of more than 1000 developers working on the code base of 2200 packages with 4 million lines of C++ and 1.4 million lines of python code. The ATLAS offline code management system is the powerful, flexible framework for processing new package versions requests, probing code changes in the Nightly Build System, migration to new platforms and compilers, deployment of production releases for worldwide access and supporting physicists with tools and interfaces for efficient software use. It maintains multi-stream, parallel development environment with about 70 multi-platform branches of nightly releases and provides vast opportunities for testing new packages, for verifying patches to existing software and for migrating to new platforms and compilers. The system evolution is currently aimed on the adoption of modern continuous integration (CI) practices focused on building nightly releases early and often, with rigorous unit and integration testing. This paper describes the CI incorporation program for the ATLAS software infrastructure. It brings modern open source tools such as Jenkins and GitLab into the ATLAS Nightly System, rationalizes hardware resource allocation and administrative operations, provides improved feedback and means to fix broken builds promptly for developers. Once adopted, ATLAS CI practices will improve and accelerate innovation cycles and result in increased confidence in new software deployments. The paper reports the status of Jenkins integration with the ATLAS Nightly System as well as short and long term plans for the incorporation of CI practices.

High resolution X-ray spectra of solar flares. V - Interpretation of inner-shell transitions in Fe XX-Fe XXIII

NASA Technical Reports Server (NTRS)

Doschek, G. A.; Feldman, U.; Cowan, R. D.

1981-01-01

The paper examines high-resolution solar flare iron line spectra recorded between 1.82 and 1.97 A by a spectrometer flown by the Naval Research Laboratory on an Air Force spacecraft launched on 1979 February 24. The emission line spectrum is due to inner-shell transitions in the ions Fe XX-Fe XXV. Using theoretical spectra and calculations of line intensities obtained by methods discussed by Merts, Cowan, and Magee (1976), electron temperatures as a function of time for two large class X flares are derived. These temperatures are deduced from intensities of lines of Fe XXII, Fe XXIII, and Fe XXIV. The determination of the differential emission measure between about 12-million and 20-million K using these temperatures is considered. The possibility of determining electron densities in flare and tokamak plasmas using the inner-shell spectra of Fe XXI and Fe XX is discussed.

The devil is in the details: Transposable element analysis of the Tasmanian devil genome.

PubMed

Nilsson, Maria A

2016-01-01

The third marsupial genome was sequenced from the Tasmanian devil ( Sarcophilus harrisii ), a species that currently is driven to extinction by a rare transmissible cancer. The transposable element (TE) landscape of the Tasmanian devil genome revealed that the main driver of retrotransposition the L ong IN terspersed E lement 1 (LINE1) seem to have become inactivated during the past 12 million years. Strangely, the S hort IN terspersed E lements (SINE), that normally hijacks the LINE1 retrotransposition system, became inactive prior to LINE1 at around 30 million years ago. The SINE inactivation was in vitro verified in several species. Here I discuss that the apparent LINE1 inactivation might be caused by a genome assembly artifact. The repetitive fraction of any genome is highly complex to assemble and the observed problems are not unique to the Tasmanian devil genome.

The devil is in the details: Transposable element analysis of the Tasmanian devil genome

PubMed Central

Nilsson, Maria A.

2016-01-01

ABSTRACT The third marsupial genome was sequenced from the Tasmanian devil (Sarcophilus harrisii), a species that currently is driven to extinction by a rare transmissible cancer. The transposable element (TE) landscape of the Tasmanian devil genome revealed that the main driver of retrotransposition the Long INterspersed Element 1 (LINE1) seem to have become inactivated during the past 12 million years. Strangely, the Short INterspersed Elements (SINE), that normally hijacks the LINE1 retrotransposition system, became inactive prior to LINE1 at around 30 million years ago. The SINE inactivation was in vitro verified in several species. Here I discuss that the apparent LINE1 inactivation might be caused by a genome assembly artifact. The repetitive fraction of any genome is highly complex to assemble and the observed problems are not unique to the Tasmanian devil genome. PMID:27066301

Source habitats for terrestrial vertebrates of focus in the interior Columbia basin: broadscale trends and management implications. Volume 1—Overview.

Treesearch

Michael J. Wisdom; Richard S. Holthausen; Barbara C. Wales; Christina D. Hargis; Victoria A. Saab; Danny C. Lee; Wendel J. Hann; Terrell D. Rich; Mary M. Rowland; Wally J. Murphy; Michelle R. Eames

2000-01-01

We defined habitat requirements (source habitats) and assessed trends in these habitats for 91 species of terrestrial vertebrates on 58 million ha (145 million acres) of public and private lands within the interior Columbia basin (hereafter referred to as the basin). We also summarized knowledge about species-road relations for each species and mapped source habitats...

Unreported Emission Lines of Rb, Ce, La, Sr, Y, Zr, Pb and Se Detected Using Laser-Induced Breakdown Spectroscopy

NASA Technical Reports Server (NTRS)

Lepore, K. H.; Mackie, J.; Dyar, M. D.; Fassett, C. I.

2017-01-01

Information on emission lines for major and minor elements is readily available from the National Institute of Standards and Technology (NIST) as part of the Atomic Spectra Database. However, tabulated emission lines are scarce for some minor elements and the wavelength ranges presented on the NIST database are limited to those included in existing studies. Previous work concerning minor element calibration curves measured using laser-induced break-down spectroscopy found evidence of Zn emission lines that were not documented on the NIST database. In this study, rock powders were doped with Rb, Ce, La, Sr, Y, Zr, Pb and Se in concentrations ranging from 10 percent to 10 parts per million. The difference between normalized spectra collected on samples containing 10 percent dopant and those containing only 10 parts per million were used to identify all emission lines that can be detected using LIBS (Laser-Induced Breakdown Spectroscopy) in a ChemCam-like configuration at the Mount Holyoke College LIBS facility. These emission spectra provide evidence of many previously undocumented emission lines for the elements measured here.

Mobile hybrid LiDAR & infrared sensing for natural gas pipeline monitoring, final report.

DOT National Transportation Integrated Search

2016-01-01

The natural gas distribution system in the U.S. has a total of 1.2 million miles of mains and about 65 million service lines as of 2012 [1]. This distribution system consists of various material types and is subjected to various threats which vary ac...

Refining Estimates of Bird Collision and Electrocution Mortality at Power Lines in the United States

PubMed Central

Loss, Scott R.; Will, Tom; Marra, Peter P.

2014-01-01

Collisions and electrocutions at power lines are thought to kill large numbers of birds in the United States annually. However, existing estimates of mortality are either speculative (for electrocution) or based on extrapolation of results from one study to all U.S. power lines (for collision). Because national-scale estimates of mortality and comparisons among threats are likely to be used for prioritizing policy and management strategies and for identifying major research needs, these estimates should be based on systematic and transparent assessment of rigorously collected data. We conducted a quantitative review that incorporated data from 14 studies meeting our inclusion criteria to estimate that between 12 and 64 million birds are killed each year at U.S. power lines, with between 8 and 57 million birds killed by collision and between 0.9 and 11.6 million birds killed by electrocution. Sensitivity analyses indicate that the majority of uncertainty in our estimates arises from variation in mortality rates across studies; this variation is due in part to the small sample of rigorously conducted studies that can be used to estimate mortality. Little information is available to quantify species-specific vulnerability to mortality at power lines; the available literature over-represents particular bird groups and habitats, and most studies only sample and present data for one or a few species. Furthermore, additional research is needed to clarify whether, to what degree, and in what regions populations of different bird species are affected by power line-related mortality. Nonetheless, our data-driven analysis suggests that the amount of bird mortality at U.S. power lines is substantial and that conservation management and policy is necessary to reduce this mortality. PMID:24991997

Dissolved Solids in Streams of the Conterminous United States

NASA Astrophysics Data System (ADS)

Anning, D. W.; Flynn, M.

2014-12-01

Studies have shown that excessive dissolved-solids concentrations in water can have adverse effects on the environment and on agricultural, municipal, and industrial water users. Such effects motivated the U.S. Geological Survey's National Water-Quality Assessment Program to develop a SPAtially-Referenced Regression on Watershed Attributes (SPARROW) model to improve the understanding of dissolved solids in streams of the United States. Using the SPARROW model, annual dissolved-solids loads from 2,560 water-quality monitoring stations were statistically related to several spatial datasets serving as surrogates for dissolved-solids sources and transport processes. Sources investigated in the model included geologic materials, road de-icers, urban lands, cultivated lands, and pasture lands. Factors affecting transport from these sources to streams in the model included climate, soil, vegetation, terrain, population, irrigation, and artificial-drainage characteristics. The SPARROW model was used to predict long-term mean annual conditions for dissolved-solids sources, loads, yields, and concentrations in about 66,000 stream reaches and corresponding incremental catchments nationwide. The estimated total amount of dissolved solids delivered to the Nation's streams is 272 million metric tons (Mt) annually, of which 194 million Mt (71%) are from geologic sources, 38 million Mt (14%) are from road de-icers, 18 million Mt (7%) are from pasture lands, 14 million Mt (5 %) are from urban lands, and 8 million Mt (3%) are from cultivated lands. The median incremental-catchment yield delivered to local streams is 26 metric tons per year per square kilometer [(Mt/yr)/km2]. Ten percent of the incremental catchments yield less than 4 (Mt/yr)/km2, and 10 percent yield more than 90 (Mt/yr)/km2. In 13% of the reaches, predicted flow-weighted concentrations exceed 500 mg/L—the U.S. Environmental Protection Agency secondary non-enforceable drinking-water standard.

Survey of Large Methane Emitters in North America

NASA Astrophysics Data System (ADS)

Deiker, S.

2017-12-01

It has been theorized that methane emissions in the oil and gas industry follow log normal or "fat tail" distributions, with large numbers of small sources for every very large source. Such distributions would have significant policy and operational implications. Unfortunately, by their very nature such distributions would require large sample sizes to verify. Until recently, such large-scale studies would be prohibitively expensive. The largest public study to date sampled 450 wells, an order of magnitude too low to effectively constrain these models. During 2016 and 2017, Kairos Aerospace conducted a series of surveys the LeakSurveyor imaging spectrometer, mounted on light aircraft. This small, lightweight instrument was designed to rapidly locate large emission sources. The resulting survey covers over three million acres of oil and gas production. This includes over 100,000 wells, thousands of storage tanks and over 7,500 miles of gathering lines. This data set allows us to now probe the distribution of large methane emitters. Results of this survey, and implications for methane emission distribution, methane policy and LDAR will be discussed.

Using Rose and Compass for Authentication

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G

2009-07-09

Many recent non-proliferation software projects include a software authentication component. In this context, 'authentication' is defined as determining that a software package performs only its intended purpose and performs that purpose correctly and reliably over many years. In addition to visual inspection by knowledgeable computer scientists, automated tools are needed to highlight suspicious code constructs both to aid the visual inspection and to guide program development. While many commercial tools are available for portions of the authentication task, they are proprietary, and have limited extensibility. An open-source, extensible tool can be customized to the unique needs of each project. ROSEmore » is an LLNL-developed robust source-to-source analysis and optimization infrastructure currently addressing large, million-line DOE applications in C, C++, and FORTRAN. It continues to be extended to support the automated analysis of binaries (x86, ARM, and PowerPC). We continue to extend ROSE to address a number of security specific requirements and apply it to software authentication for non-proliferation projects. We will give an update on the status of our work.« less

Stellar Clusters in the NGC 6334 Star-Forming Complex

NASA Astrophysics Data System (ADS)

Feigelson, Eric D.; Martin, Amanda L.; McNeill, Collin J.; Broos, Patrick S.; Garmire, Gordon P.

2009-07-01

The full stellar population of NGC 6334, one of the most spectacular regions of massive star formation in the nearby Galaxy, has not been well sampled in past studies. We analyze here a mosaic of two Chandra X-ray Observatory images of the region using sensitive data analysis methods, giving a list of 1607 faint X-ray sources with arcsecond positions and approximate line-of-sight absorption. About 95% of these are expected to be cluster members, most lower mass pre-main-sequence stars. Extrapolating to low X-ray levels, the total stellar population is estimated to be 20,000-30,000 pre-main-sequence stars. The X-ray sources show a complicated spatial pattern with ~10 distinct star clusters. The heavily obscured clusters are mostly associated with previously known far-infrared sources and radio H II regions. The lightly obscured clusters are mostly newly identified in the X-ray images. Dozens of likely OB stars are found, both in clusters and dispersed throughout the region, suggesting that star formation in the complex has proceeded over millions of years. A number of extraordinarily heavily absorbed X-ray sources are associated with the active regions of star formation.

New GALEX UV Data Products At MAST For Stellar Astrophysics

NASA Astrophysics Data System (ADS)

Shiao, Bernie; Fleming, S. W.; Million, C.; Seibert, M.; Bianchi, L.; Thompson, R.; Tseng, S.; Adler, W. J.; Hubbard, M.; Levay, K.; Madore, B. F.; Martin, C. D.; Nieto-Santisteban, M. A.; Sahai, R.; Schiminovich, D.; White, R. L.; Wyder, T. K.

2014-01-01

The Galaxy Evolution Explorer (GALEX) mission ended in June 2013 after ten years in orbit. Its FUV and NUV microchannel plate detectors were used to conduct a variety of direct imaging and spectroscopic astronomical surveys with various depths and sky coverage, recording individual photon events with a time resolution of five thousandths of a second. Although the mission has ended, MAST is continuing to provide new data products as the mission transitions to a legacy archive. One product is the GCAT (Seibert et al., in prep), a catalog of GALEX sources across the entire GR6 data release that removes duplicate objects found in the GALEX MCAT. The GCAT defines "primary" NUV and FUV fluxes within the AIS and MIS surveys 40 million and 22 million sources, respectively), accounting for tile overlaps, and with visual inspection of every tile to flag artifacts and conduct other quality control checks. Another catalog of unique sources is that of Bianchi et al. (2013). Similar to the GCAT, their catalog produces a list of distinct GALEX sources in both the FUV and NUV from the AIS and MIS surveys, and includes data from GR7 (through the end of 2012). They have also cross-matched their sources with SDSS DR9, GSC-II, PanSTARRS, and 2MASS. We review access options for these catalogs, including updated matches between the GCAT and SDSS / Kepler available at MAST. In addition to these unique GALEX source catalogs, MAST will provide a database and software package that archives each of the ~1.5 trillion photon events detected over the lifetime of the mission. For the first time, users will be able to create calibrated lightcurves, intensity maps, and animated movies from any set of photons selected across any tile, and with specified aperture sizes, coordinates, and time steps. Users can access the data using either a python-based command-line software package, through a web interface at MAST, or (eventually) through CasJobs using direct SQL queries. We present some example GALEX lightcurves and images using this new data product to highlight just some of the possibilities available for users to mine the GALEX photon database, particularly with variable sources.

Water Use in Oklahoma 1950-2005

USGS Publications Warehouse

Tortorelli, Robert L.

2009-01-01

Comprehensive planning for water resources development and use in Oklahoma requires a historical perspective on water resources. The U.S. Geological Survey, in cooperation with the Oklahoma Water Resources Board, summarized the 1950-2005 water-use information for Oklahoma. This report presents 1950-2005 estimates of freshwater withdrawal for water use in Oklahoma by source and category in 5-year intervals. Withdrawal source was either surface water or groundwater. Withdrawal categories include: public supply, irrigation, livestock and aquaculture, thermoelectric-power generation (cooling water), domestic and commercial, and industrial and mining. Withdrawal data were aggregated and tabulated by county, major river basin, and principal aquifer. The purpose of this report is to summarize water-use data in Oklahoma through: (1) presentation of detailed information on freshwater withdrawals by source, county, major river basin, and principal aquifer for 2005; (2) comparison of water use by source, category, major river basin, and principal aquifer at 5-year intervals from 1990-2005; and (3) comparison of water use on a statewide basis by source and category at 5-year intervals from 1950-2005. Total withdrawals from surface-water and groundwater sources during 2005 were 1,559 million gallons per day-989 million gallons a day or 63 percent from surface-water sources and 570 million gallons per day or 37 percent from groundwater sources. The three largest water use categories were: public supply, 646 million gallons per day or 41 percent of total withdrawals; irrigation, 495 million gallons per day or 32 percent of total withdrawals; and livestock and aquaculture, 181 million gallons per day or 12 percent of total withdrawals. All other categories were 237 million gallons per day or 15 percent of total withdrawals. The influence of public supply on the total withdrawals can be seen in the eastern two-thirds of Oklahoma; whereas, the influence of irrigation on total withdrawals can be seen in the western third of Oklahoma. Surface-water sources were dominant in the eastern half of Oklahoma and groundwater sources were dominant in the western half of Oklahoma. Public supply withdrawals increased steadily from 1990-2000 and then decreased slightly in 2005, mainly because of a decrease in surface-water withdrawals. Irrigation withdrawals increased from 1990-1995 and then decreased steadily to 2005. Total livestock and aquaculture withdrawals steadily increased from 1990-2005. The largest increase in the other categories was for thermoelectric power generation that has steadily increased and almost doubled from 1990-2005. Surface-water sources have been increasing in importance from 1950-2005, in part because of the increasing percentage of surface-water for public supply as the total population of Oklahoma and population served by surface-water sources increased. Groundwater sources have been generally decreasing in importance as a percentage of total withdrawals in recent years. However, the magnitude of groundwater withdrawals was greatly dependent on irrigation withdrawals and specifically irrigated acreage in the panhandle.

40 CFR 464.25 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) EFFLUENT GUIDELINES AND STANDARDS METAL MOLDING AND CASTING POINT SOURCE CATEGORY Copper Casting... Maximum for monthly average kg/1000 kkg (pounds per million pounds) of metal poured Copper (T) 0.0307 0... any 1 day Maximum for monthly average kg/1,000 kkg (pounds per million pounds) of metal poured Copper...

Skills for Work in the Future: A Youth Perspective

ERIC Educational Resources Information Center

Lyngdoh, Bremley W. B.

2005-01-01

According to a 2004 International Labour Organization (ILO) report, young people represent 130 million of the world's 550 million working poor who are unable to lift themselves and their families above the equivalent of the $1 per day poverty line. These young people struggle to survive, often performing work under unsatisfactory conditions in the…

For Athletics, a Billion-Dollar Goal Line

ERIC Educational Resources Information Center

Wolverton, Brad

2009-01-01

The nation's biggest athletics departments are quietly trying to raise hundreds of millions of dollars for separate sports endowments, heating up the competition for donors and raising questions about institutional priorities during the economic crunch. At least eight programs hope to bring in more than $100-million each to defray the rising costs…

The Path for the Development and Release of Heat Tolerant Soybean Lines

USDA-ARS?s Scientific Manuscript database

High ambient temperatures can damage soybean seed. Heat is recognized by the crop insurance industry as a major cause for monetary losses to producers. The USDA Risk Management Agency reported payouts to soybean farmers of more than $247 million on over 1.62 million hectares for losses due to heat...

Estimated use of water in Colorado, 1985

USGS Publications Warehouse

Litke, D.W.; Appel, C.L.

1989-01-01

Water-use data was collected for the State of Colorado as part of the U.S. Geological Survey 's National Water-Use Information Program. An estimated 20,800 million gal/day of water were used in Colorado during 1985. 89% came from surface water sources and 11% came from groundwater sources. Public supply systems provided 4% of all water used in Colorado during 1985, but provided 80% of all commercial, domestic, and industrial water used. An estimated 4,840 million gal/day of water were consumed during 1985; return flows amounted to 16,000 million gallons per day. Of all water used, 60% was used for irrigation, 35% for hydroelectric power generation, and the remaining 5% for commercial, domestic, industrial, livestock, mining, and other uses. The most water was used in Montrose (3,260 million gal/day), Mesa (1,950 million gal/day), and Gunnison (1,520 million gal/day) Counties. The predominant water uses in these counties were hydroelectric power and irrigation. (USGS)

Million Trees Los Angeles: Carbon dioxide sink or source?

Treesearch

E.G. McPherson; A. Kendall; S. Albers

2015-01-01

This study seeks to answer the question, 'Will the Million Trees LA (MTLA) programme be a CO2 sink or source?' Using surveys, interviews, field sampling and computer simulation of tree growth and survival over a 40-year period, we developed the first process-based life cycle inventory of CO2 for a large tree...

Advancing Learning by Countering the Effects of Poverty

ERIC Educational Resources Information Center

Arnett-Hartwick, Sally E.; Walters, Connor M.

2016-01-01

The negative effects of poverty have a pervasive impact on the well-being of individuals, families, and communities. More than 45 million people in the United States hover around the poverty line, about 20% of whom (9.02 million) are children (U. S. Census Bureau, 2014). These children are at great risk for continuing the cycle of living in…

A calibrated chronology of biochemistry reveals a stem line of descent responsible for planetary biodiversity.

PubMed

Caetano-Anollés, Gustavo; Mittenthal, Jay E; Caetano-Anollés, Derek; Kim, Kyung Mo

2014-01-01

Time-calibrated phylogenomic trees of protein domain structure produce powerful chronologies describing the evolution of biochemistry and life. These timetrees are built from a genomic census of millions of encoded proteins using models of nested accumulation of molecules in evolving proteomes. Here we show that a primordial stem line of descent, a propagating series of pluripotent cellular entities, populates the deeper branches of the timetrees. The stem line produced for the first time cellular grades ~2.9 billion years (Gy)-ago, which slowly turned into lineages of superkingdom Archaea. Prompted by the rise of planetary oxygen and aerobic metabolism, the stem line also produced bacterial and eukaryal lineages. Superkingdom-specific domain repertoires emerged ~2.1 Gy-ago delimiting fully diversified Bacteria. Repertoires specific to Eukarya and Archaea appeared 300 millions years later. Results reconcile reductive evolutionary processes leading to the early emergence of Archaea to superkingdom-specific innovations compatible with a tree of life rooted in Bacteria.

Calling on a million minds for community annotation in WikiProteins

PubMed Central

Mons, Barend; Ashburner, Michael; Chichester, Christine; van Mulligen, Erik; Weeber, Marc; den Dunnen, Johan; van Ommen, Gert-Jan; Musen, Mark; Cockerill, Matthew; Hermjakob, Henning; Mons, Albert; Packer, Abel; Pacheco, Roberto; Lewis, Suzanna; Berkeley, Alfred; Melton, William; Barris, Nickolas; Wales, Jimmy; Meijssen, Gerard; Moeller, Erik; Roes, Peter Jan; Borner, Katy; Bairoch, Amos

2008-01-01

WikiProteins enables community annotation in a Wiki-based system. Extracts of major data sources have been fused into an editable environment that links out to the original sources. Data from community edits create automatic copies of the original data. Semantic technology captures concepts co-occurring in one sentence and thus potential factual statements. In addition, indirect associations between concepts have been calculated. We call on a 'million minds' to annotate a 'million concepts' and to collect facts from the literature with the reward of collaborative knowledge discovery. The system is available for beta testing at . PMID:18507872

Apoptosis Activation in Human Lung Cancer Cell Lines by a Novel Synthetic Peptide Derived from Conus californicus Venom

PubMed Central

Oroz-Parra, Irasema; Navarro, Mario; Cervantes-Luevano, Karla E.; Álvarez-Delgado, Carolina; Salvesen, Guy; Sanchez-Campos, Liliana N.; Licea-Navarro, Alexei F.

2016-01-01

Lung cancer is one of the most common types of cancer in men and women and a leading cause of death worldwide resulting in more than one million deaths per year. The venom of marine snails Conus contains up to 200 pharmacologically active compounds that target several receptors in the cell membrane. Due to their diversity and specific binding properties, Conus toxins hold great potential as source of new drugs against cancer. We analyzed the cytotoxic effect of a 17-amino acid synthetic peptide (s-cal14.1a) that is based on a native toxin (cal14.1a) isolated from the sea snail Conus californicus. Cytotoxicity studies in four lung cancer cell lines were complemented with measurement of gene expression of apoptosis-related proteins Bcl-2, BAX and the pro-survival proteins NFκB-1 and COX-2, as well as quantification of caspase activity. Our results showed that H1299 and H1437 cell lines treated with s-call4.1a had decreased cell viability, activated caspases, and reduced expression of the pro-survival protein NFκB-1. To our knowledge, this is the first report describing activation of apoptosis in human lung cancer cell lines by s-cal14.1a and we offer insight into the possible mechanism of action. PMID:26861394

SUBTLEX-CH: Chinese Word and Character Frequencies Based on Film Subtitles

PubMed Central

Cai, Qing; Brysbaert, Marc

2010-01-01

Background Word frequency is the most important variable in language research. However, despite the growing interest in the Chinese language, there are only a few sources of word frequency measures available to researchers, and the quality is less than what researchers in other languages are used to. Methodology Following recent work by New, Brysbaert, and colleagues in English, French and Dutch, we assembled a database of word and character frequencies based on a corpus of film and television subtitles (46.8 million characters, 33.5 million words). In line with what has been found in the other languages, the new word and character frequencies explain significantly more of the variance in Chinese word naming and lexical decision performance than measures based on written texts. Conclusions Our results confirm that word frequencies based on subtitles are a good estimate of daily language exposure and capture much of the variance in word processing efficiency. In addition, our database is the first to include information about the contextual diversity of the words and to provide good frequency estimates for multi-character words and the different syntactic roles in which the words are used. The word frequencies are freely available for research purposes. PMID:20532192

Differential Subsidence in Mexico City and its Consequences to the Collective Transport System (Metro)

NASA Astrophysics Data System (ADS)

Solano Rojas, D. E.; Wdowinski, S.; Cabral, E.; Zhang, Y.; Torres, Y.

2015-12-01

Mexico City is one of the most populated metropolitans in the world, with more than 20 millions inhabitants. It is located above a sequence of deformable unconsolidated lacustrine sediments interlayered with strong volcanic rocks. These natural conditions combined with massive groundwater extraction, caused the city to subside unevenly, at rates from 0 to ~370 mm/yr, which we term differential subsidence. Our study focuses on the Collective Transport System (Metro), the massive, widely used transportation system in the city. It has been in operation since 1969. The Metro system carries an average of more than four million passengers per day along its 218 km of railways. This system has been occasionally damaged by ground deformation, in particular Line 12, in which 50% of its stations where shut down just 2.5 years after the beginning of its operation due to faults, "waves" and "bumps" along the line. In this study we used Interferometric Synthetic Aperture Radar (InSAR) observations to monitor land subsidence throughout the city and infer differential subsidence along the main Metro lines. Our analysis is based on 34 TerraSAR-X and 36 COSMO-SkyMed high-resolution scenes acquired from mid 2011 to mid 2013. The data were processed using the StaMPS InSAR time series technique, which calculates ground displacement time series for more than 2.5 million selected measurement points, typically separated 3-15 meters apart. The differential subsidence along the Metro lines was calculated by averaging subsidence rate within a 30 m radius circles, every 60 m along the lines. We found that the segments with the most differential deformation are in lines 4, 5, 9, A, B and 12. Our easy-to-implement method can be applied to permanent monitor deformation along the railways, as well as serve as a guide for the development of new lines of the Metro system prospected by Mexico's City government.

40 CFR 464.26 - Pretreatment standards for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS METAL MOLDING AND CASTING POINT SOURCE CATEGORY Copper Casting Subcategory § 464.26... million pounds) of metal poured Copper (T) 0.0307 0.0168 Lead (T) 0.0211 0.0104 Zinc (T) 0.0303 0.0116 TTO... kkg (pounds per million pounds) of metal poured Copper (T) 0.928 0.506 Lead (T) 0.639 0.314 Zinc (T) 0...

40 CFR 464.46 - Pretreatment standards for new sources.

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUIDELINES AND STANDARDS METAL MOLDING AND CASTING POINT SOURCE CATEGORY Zinc Casting Subcategory § 464.46... million pounds) of metal poured Copper (T) 0.0344 0.0187 Lead (T) 0.0237 0.0116 Zinc (T) 0.0339 0.0129 TTO... million pounds) of metal poured Copper (T) 0.0066 0.0036 Lead (T) 0.0046 0.0022 Zinc (T) 0.0066 0.0025...

40 CFR 464.46 - Pretreatment standards for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS METAL MOLDING AND CASTING POINT SOURCE CATEGORY Zinc Casting Subcategory § 464.46... million pounds) of metal poured Copper (T) 0.0344 0.0187 Lead (T) 0.0237 0.0116 Zinc (T) 0.0339 0.0129 TTO... million pounds) of metal poured Copper (T) 0.0066 0.0036 Lead (T) 0.0046 0.0022 Zinc (T) 0.0066 0.0025...

Save the Children Nonformal Education and Early Childhood Development Activities in Rural Nepal.

ERIC Educational Resources Information Center

Reinhold, Amy Jo

In 1981, Save the Children (SC) opened an office in Nepal to support projects related to health, education, income generation, and resource management. Statistics show that between 7 and 8 million of Nepal's 19 million people live below the poverty line, and almost 2 out of 3 adolescent girls do not attend school, placing the overall female…

Class III / short line system inventory to determine 286,000 lb (129,844 kg) railcar operational status in Kansas : final report.

DOT National Transportation Integrated Search

2017-08-01

The rail industrys recent shift towards larger and heavier railcars has influenced Class III/short line railroad operation and track maintenance costs. Class III railroads earn less than $38.1 million in annual revenue and generally operate first ...

Class III / short line system inventory to determine 286,000 lb (129,844 kg) railcar operational status in Kansas : technical summary.

DOT National Transportation Integrated Search

2017-08-01

The rail industrys recent shift towards larger and heavier railcars has influenced Class III/short line railroad operation and track maintenance costs. Class III railroads earn less than $38.1 million in annual revenue and generally operate first ...

On-line application of near-infrared spectroscopy for monitoring water levels in parts per million in a manufacturing-scale distillation process.

PubMed

Lambertus, Gordon; Shi, Zhenqi; Forbes, Robert; Kramer, Timothy T; Doherty, Steven; Hermiller, James; Scully, Norma; Wong, Sze Wing; LaPack, Mark

2014-01-01

An on-line analytical method based on transmission near-infrared spectroscopy (NIRS) for the quantitative determination of water concentrations (in parts per million) was developed and applied to the manufacture of a pharmaceutical intermediate. Calibration models for water analysis, built at the development site and applied at the manufacturing site, were successfully demonstrated during six manufacturing runs at a 250-gallon scale. The water measurements will be used as a forward-processing control point following distillation of a toluene product solution prior to use in a Grignard reaction. The most significant impact of using this NIRS-based process analytical technology (PAT) to replace off-line measurements is the significant reduction in the risk of operator exposure through the elimination of sampling of a severely lachrymatory and mutagenic compound. The work described in this report illustrates the development effort from proof-of-concept phase to manufacturing implementation.

A genetic variation map for chicken with 2.8 million single nucleotide polymorphisms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wong, G K; Hillier, L; Brandstrom, M

2005-02-20

We describe a genetic variation map for the chicken genome containing 2.8 million single nucleotide polymorphisms (SNPs), based on a comparison of the sequences of 3 domestic chickens (broiler, layer, Silkie) to their wild ancestor Red Jungle Fowl (RJF). Subsequent experiments indicate that at least 90% are true SNPs, and at least 70% are common SNPs that segregate in many domestic breeds. Mean nucleotide diversity is about 5 SNP/kb for almost every possible comparison between RJF and domestic lines, between two different domestic lines, and within domestic lines--contrary to the idea that domestic animals are highly inbred relative to theirmore » wild ancestors. In fact, most of the SNPs originated prior to domestication, and there is little to no evidence of selective sweeps for adaptive alleles on length scales of greater than 100 kb.« less

NASA cancels carbon monitoring research program

NASA Astrophysics Data System (ADS)

Voosen, Paul

2018-05-01

The administration of President Donald Trump has waged a broad attack on climate science conducted by NASA, including proposals to cut the budget of earth science research and kill off the Orbiting Carbon Observatory 3 mission. Congress has fended these attacks off—with one exception. NASA has moved ahead with plans to end the Carbon Monitoring System, a $10-million-a-year research line that has helped stitch together observations of sources and sinks of methane and carbon dioxide into high-resolution models of the planet's flows of carbon, the agency confirmed to Science. The program, begun in 2010, has developed tools to improve estimates of carbon stocks in forests, especially, from Alaska to Indonesia. Ending it, researchers say, will complicate future efforts to monitor and verify national emission cuts stemming from the Paris climate deal.

GARLIC, A SHIELDING PROGRAM FOR GAMMA RADIATION FROM LINE- AND CYLINDER- SOURCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roos, M.

1959-06-01

GARLlC is a program for computing the gamma ray flux or dose rate at a shielded isotropic point detector, due to a line source or the line equivalent of a cylindrical source. The source strength distribution along the line must be either uniform or an arbitrary part of the positive half-cycle of a cosine function The line source can be orierted arbitrarily with respect to the main shield and the detector, except that the detector must not be located on the line source or on its extensionThe main source is a homogeneous plane slab in which scattered radiation is accountedmore » for by multiplying each point element of the line source by a point source buildup factor inside the integral over the point elements. Between the main shield and the line source additional shields can be introduced, which are either plane slabs, parallel to the main shield, or cylindrical rings, coaxial with the line source. Scattered radiation in the additional shields can only be accounted for by constant build-up factors outside the integral. GARLlC-xyz is an extended version particularly suited for the frequently met problem of shielding a room containing a large number of line sources in diHerent positions. The program computes the angles and linear dimensions of a problem for GARLIC when the positions of the detector point and the end points of the line source are given as points in an arbitrary rectangular coordinate system. As an example the isodose curves in water are presented for a monoenergetic cosine-distributed line source at several source energies and for an operating fuel element of the Swedish reactor R3, (auth)« less

12 Scientists Will Share $120-Million from Saudis

ERIC Educational Resources Information Center

Guterman, Lila

2008-01-01

This spring 12 scientists found themselves in an unusual position--they have to figure out how to spend $2-million every year for the next five years. The money adds up to $10-million per researcher. In May the researchers made a pilgrimage to the source of the generous grants: King Abdullah University of Science and Technology, a graduate…

Medical Review Process and License Disposition of Drivers Referred by Law Enforcement and Other Sources in Virginia

DOT National Transportation Integrated Search

2011-07-01

This year, 2011, the first of the Baby Boom generation begins to reach age 65. This 65- : and-older age group, which numbered 35 million in the United States in 2000, will grow to more : than 54 million by 2020, and will exceed 70 million by 2030. By...

Trail Creek II: Modeling Flow and E. Coli Concentrations in a Small Urban Stream using SWAT

NASA Astrophysics Data System (ADS)

Radcliffe, D. E.; Saintil, T.

2017-12-01

Pathogens are one of the leading causes of stream and river impairment in the State of Georgia. The common presence of fecal bacteria is driven by several factors including rapid population growth stressing pre-existing and ageing infrastructure, urbanization and poor planning, increase percent imperviousness, urban runoff, municipal discharges, sewage, pet/wildlife waste and leaky septic tanks. The Trail Creek watershed, located in Athens-Clarke County, Georgia covers about 33 km2. Stream segments within Trail Creek violate the GA standard due to high levels of fecal coliform bacteria. In this study, the Soil and Water Assessment Tool (SWAT) modeling software was used to predict E. coli bacteria concentrations during baseflow and stormflow. Census data from the county was used for human and animal population estimates and the Fecal Indicator Tool to generate the number of colony forming units of E. Coli for each source. The model was calibrated at a daily time step with one year of monitored streamflow and E. coli bacteria data using SWAT-CUP and the SUFI2 algorithm. To simulate leaking sewer lines, we added point sources in the five subbasins in the SWAT model with the greatest length of sewer line within 50 m of the stream. The flow in the point sources were set to 5% of the stream flow and the bacteria count set to that of raw sewage (30,000 cfu/100 mL). The calibrated model showed that the average load during 2003-2013 at the watershed outlet was 13 million cfu per month. Using the calibrated model, we simulated scenarios that assumed leaking sewers were repaired in one of the five subbasins with point sources. The reduction ranged from 10 to 46%, with the largest reduction in subbasin in the downtown area. Future modeling work will focus on the use of green infrastructure to address sources of bacteria.

Roadmap to control HBV and HDV epidemics in China

DOE PAGES

Goyal, Ashish; Murray, John M.

2017-04-23

Hepatitis B virus (HBV) is endemic in China. Almost 10% of HBV infected individuals are also infected with hepatitis D virus (HDV) which has a 5–10 times higher mortality rate than HBV mono-infection. The aim of this manuscript is to devise strategies that can not only control HBV infections but also HDV infections in China under the current health care budget in an optimal manner. Furthermore, using a mathematical model, an annual budget of 10 billion dollars was optimally allocated among five interventions namely, testing and HBV adult vaccination, treatment for mono-infected and dually-infected individuals, second line treatment for HBVmore » mono-infections, and awareness programs. As a result, we determine that the optimal strategy is to test and treat both infections as early as possible while applying awareness programs at full intensity. Under this strategy, an additional 19.8 million HBV, 1.9 million HDV infections and 0.25 million lives will be saved over the next 10 years at a cost-savings of 79 billion dollars than performing no intervention. Introduction of second line treatment does not add a significant economic burden yet prevents 1.4 million new HBV infections and 15,000 new HDV infections. In conclusion, test and treatment programs are highly efficient in reducing HBV and HDV prevalence in the population. Under the current health budget in China, not only test and treat programs but awareness programs and second line treatment can also be implemented that minimizes prevalence and mortality, and maximizes economic benefits.« less

Roadmap to control HBV and HDV epidemics in China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goyal, Ashish; Murray, John M.

Hepatitis B virus (HBV) is endemic in China. Almost 10% of HBV infected individuals are also infected with hepatitis D virus (HDV) which has a 5–10 times higher mortality rate than HBV mono-infection. The aim of this manuscript is to devise strategies that can not only control HBV infections but also HDV infections in China under the current health care budget in an optimal manner. Furthermore, using a mathematical model, an annual budget of 10 billion dollars was optimally allocated among five interventions namely, testing and HBV adult vaccination, treatment for mono-infected and dually-infected individuals, second line treatment for HBVmore » mono-infections, and awareness programs. As a result, we determine that the optimal strategy is to test and treat both infections as early as possible while applying awareness programs at full intensity. Under this strategy, an additional 19.8 million HBV, 1.9 million HDV infections and 0.25 million lives will be saved over the next 10 years at a cost-savings of 79 billion dollars than performing no intervention. Introduction of second line treatment does not add a significant economic burden yet prevents 1.4 million new HBV infections and 15,000 new HDV infections. In conclusion, test and treatment programs are highly efficient in reducing HBV and HDV prevalence in the population. Under the current health budget in China, not only test and treat programs but awareness programs and second line treatment can also be implemented that minimizes prevalence and mortality, and maximizes economic benefits.« less

Extracting and connecting chemical structures from text sources using chemicalize.org.

PubMed

Southan, Christopher; Stracz, Andras

2013-04-23

Exploring bioactive chemistry requires navigating between structures and data from a variety of text-based sources. While PubChem currently includes approximately 16 million document-extracted structures (15 million from patents) the extent of public inter-document and document-to-database links is still well below any estimated total, especially for journal articles. A major expansion in access to text-entombed chemistry is enabled by chemicalize.org. This on-line resource can process IUPAC names, SMILES, InChI strings, CAS numbers and drug names from pasted text, PDFs or URLs to generate structures, calculate properties and launch searches. Here, we explore its utility for answering questions related to chemical structures in documents and where these overlap with database records. These aspects are illustrated using a common theme of Dipeptidyl Peptidase 4 (DPPIV) inhibitors. Full-text open URL sources facilitated the download of over 1400 structures from a DPPIV patent and the alignment of specific examples with IC50 data. Uploading the SMILES to PubChem revealed extensive linking to patents and papers, including prior submissions from chemicalize.org as submitting source. A DPPIV medicinal chemistry paper was completely extracted and structures were aligned to the activity results table, as well as linked to other documents via PubChem. In both cases, key structures with data were partitioned from common chemistry by dividing them into individual new PDFs for conversion. Over 500 structures were also extracted from a batch of PubMed abstracts related to DPPIV inhibition. The drug structures could be stepped through each text occurrence and included some converted MeSH-only IUPAC names not linked in PubChem. Performing set intersections proved effective for detecting compounds-in-common between documents and merged extractions. This work demonstrates the utility of chemicalize.org for the exploration of chemical structure connectivity between documents and databases, including structure searches in PubChem, InChIKey searches in Google and the chemicalize.org archive. It has the flexibility to extract text from any internal, external or Web source. It synergizes with other open tools and the application is undergoing continued development. It should thus facilitate progress in medicinal chemistry, chemical biology and other bioactive chemistry domains.

Estimated water use in South Dakota, 1985

USGS Publications Warehouse

Benson, Rick D.; Winterton, J.E.

1988-01-01

Water use in South Dakota during 1985 is estimated to have been 674 million gal/day. This is a slight decrease from the 1980 estimate of 690 million gal/day. Of the total use, 63% was from surface-water sources and 37% was from groundwater sources. About 75% of the total water use was for agriculture, 16% was for domestic and commercial use, 8% was for industrial and mining use, and 1% was for thermoelectric and geothermal uses. Of the total used, 361 million gal/day were consumed and 313 million gal/day were returned to the surface- and groundwater system. Water use by agriculture, the largest user, was mostly for irrigation. Total use was 516,000 acre-ft (460 million gal/day) for irrigation of 397,000 acres. Non-irrigation use, mainly for livestock, was 47.1 million gal/day. About 12% of the total use was by public-water suppliers. Seventy-five percent of the deliveries by public-water suppliers were for domestic use by 78% of the population. In addition to offstream use, instream use was substantial because of hydroelectric-power generation by the four dams on the Missouri River. During 1985, 60,500 million gal/day were used to generate 6,095 gigawatt-hr of electricity. (USGS)

Water Planetary and Cometary Atmospheres: H2O/HDO Transmittance and Fluorescence Models

NASA Technical Reports Server (NTRS)

Villanueva, G. L.; Mumma, M. J.; Bonev, B. P.; Novak, R. E.; Barber, R. J.; DiSanti, M. A.

2012-01-01

We developed a modern methodology to retrieve water (H2O) and deuterated water (HDO) in planetary and cometary atmospheres, and constructed an accurate spectral database that combines theoretical and empirical results. Based on a greatly expanded set of spectroscopic parameters, we built a full non-resonance cascade fluorescence model and computed fluorescence efficiencies for H2O (500 million lines) and HDO (700 million lines). The new line list was also integrated into an advanced terrestrial radiative transfer code (LBLRTM) and adapted to the CO2 rich atmosphere of Mars, for which we adopted the complex Robert-Bonamy formalism for line shapes. We then retrieved water and D/H in the atmospheres of Mars, comet C/2007 WI, and Earth by applying the new formalism to spectra obtained with the high-resolution spectrograph NIRSPEC/Keck II atop Mauna Kea (Hawaii). The new model accurately describes the complex morphology of the water bands and greatly increases the accuracy of the retrieved abundances (and the D/H ratio in water) with respect to previously available models. The new model provides improved agreement of predicted and measured intensities for many H2O lines already identified in comets, and it identifies several unassigned cometary emission lines as new emission lines of H2O. The improved spectral accuracy permits retrieval of more accurate rotational temperatures and production rates for cometary water.

Mapping the Asymmetric Thick Disk. II. Distance, Size, and Mass of the Hercules Thick Disk Cloud

NASA Astrophysics Data System (ADS)

Larsen, Jeffrey A.; Cabanela, Juan E.; Humphreys, Roberta M.

2011-04-01

The Hercules Thick Disk Cloud was initially discovered as an excess in the number of faint blue stars between Quadrants 1 and 4 of the Galaxy. The origin of the Cloud could be an interaction with the disk bar, a triaxial Thick Disk, or a merger remnant or stream. To better map the spatial extent of the Cloud along the line of sight, we have obtained multi-color UBVR photometry for 1.2 million stars in 63 fields each of approximately 1 deg2. Our analysis of the fields beyond the apparent boundaries of the excess has already ruled out a triaxial Thick Disk as a likely explanation. In this paper, we present our results for the star counts over all of our fields, determine the spatial extent of the overdensity across and along the line of sight, and estimate the size and mass of the Cloud. Using photometric parallaxes, the stars responsible for the excess are between 1 and 6 kpc from the Sun, 0.5-4 kpc above the Galactic plane, and extend approximately 3-4 kpc across our line of sight. The Cloud is thus a major substructure in the Galaxy. The distribution of the excess along our sight lines corresponds with the density contours of the bar in the Disk, and its most distant stars are directly over the bar. We also see through the Cloud to its far side. Over the entire 500 deg2 of the sky containing the Cloud, we estimate more than 5.6 million stars and 1.9 million solar masses of material. If the overdensity is associated with the bar, it would exceed 1.4 billion stars and more than 50 million solar masses. Finally, we argue that the Hercules-Aquila Cloud is actually the Hercules Thick Disk Cloud.

MAPPING THE ASYMMETRIC THICK DISK. II. DISTANCE, SIZE, AND MASS OF THE HERCULES THICK DISK CLOUD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larsen, Jeffrey A.; Cabanela, Juan E.; Humphreys, Roberta M., E-mail: larsen@usna.edu, E-mail: cabanela@mnstate.edu, E-mail: roberta@umn.edu

2011-04-15

The Hercules Thick Disk Cloud was initially discovered as an excess in the number of faint blue stars between Quadrants 1 and 4 of the Galaxy. The origin of the Cloud could be an interaction with the disk bar, a triaxial Thick Disk, or a merger remnant or stream. To better map the spatial extent of the Cloud along the line of sight, we have obtained multi-color UBVR photometry for 1.2 million stars in 63 fields each of approximately 1 deg{sup 2}. Our analysis of the fields beyond the apparent boundaries of the excess has already ruled out a triaxialmore » Thick Disk as a likely explanation. In this paper, we present our results for the star counts over all of our fields, determine the spatial extent of the overdensity across and along the line of sight, and estimate the size and mass of the Cloud. Using photometric parallaxes, the stars responsible for the excess are between 1 and 6 kpc from the Sun, 0.5-4 kpc above the Galactic plane, and extend approximately 3-4 kpc across our line of sight. The Cloud is thus a major substructure in the Galaxy. The distribution of the excess along our sight lines corresponds with the density contours of the bar in the Disk, and its most distant stars are directly over the bar. We also see through the Cloud to its far side. Over the entire 500 deg{sup 2} of the sky containing the Cloud, we estimate more than 5.6 million stars and 1.9 million solar masses of material. If the overdensity is associated with the bar, it would exceed 1.4 billion stars and more than 50 million solar masses. Finally, we argue that the Hercules-Aquila Cloud is actually the Hercules Thick Disk Cloud.« less

40 CFR 280.95 - Financial test of self-insurance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... least $10 million? ___ 8. Is line 6 at least 10 times line 3? ___ 9. Have financial statements for the.... (f) The Director of the implementing agency may require reports of financial condition at any time... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Financial test of self-insurance. 280...

40 CFR 467.36 - Pretreatment standards for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of extruded Chromium 0.13 0.05 Cyanide... monthly average mg/off-kg (lb/million off-lbs) of hard alloy aluminum extruded Chromium 0.11 0.05 Cyanide... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum cast Chromium 0.49 0.20...

The Trans-African Hydro-Meteorological Observatory: Early results from the crowd sourcing competition

NASA Astrophysics Data System (ADS)

van de Giesen, Nick; Hilkhuijsen, Tanja; Hut, Rolf; Andreini, Marc; Selker, John

2013-04-01

The Trans-African Hydro-Meteorological Observatory (www.tahmo.org) is an international initiative with the objective to develop, build, and operate 20,000 hydro-meteorological measurement stations in sub-Saharan Africa. TAHMO tries to integrate science with education. At the same time, we try to make the initiative financially sustainable by developing and rolling out viable business development. Estimated total costs for establishing the network will be in the order of US 20 million, whereas operational costs will be around US 2 million per year. The stations need to be designed in accordance to a set of rules that serves easy deployment and operation, such as absence of moving parts and cavities, self- and cross calibration of sensors, and low cost (€ 200-300 per station). There are some promising first results in this respect. The presentation will focus on recent activities, specifically concerning crowd sourcing activities at African universities. This competition (http://tahmo.info/sensor-design-competition) consists of two rounds. The first round is open to any academic or research group in Africa and asks for the design of an innovative robust sensor in line with the TAHMO design criteria. The top twenty teams with the best designs will receive a "Maker Package" that will allow them to build and test the sensors. The final top ten design teams will meet in Nairobi in August 2013 to tinker and collaborate for one week and to integrate the sensors into a standard weather station. The deadline for the first round is 1 March 2013 and the results from this round will be presented.

Annual Review of Progress in Applied Computational Electromagnetics (6th), Held in Monterey, California on March 19-22, 1990

DTIC Science & Technology

1990-01-01

the six fields will have two million cell locations. The table below shows the total allocation of 392 chips across fields and banks. To allow for...future growth, we allocate 16 wires for addressing both the rows and columns. eU 4 MBit locations bytes bits Chips (millions) (millions) (millions) per...sources apt to appear in most problems. If material parameters change during a run, then time must be allocated to read these constants into their

Thermal storage system flops at Illinois State office building

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ponczak, G.

1986-02-03

A thermal storage and electric resistive heating system in the new State of Illinois building in Chicago has used about 65% more electricity in its first year of operation than building designers originally predicted, according to state government sources. The state proposes to spend about $2 million to fine tune the system this year. Total first year electricity usage for the all-electric, 1.15 million square foot building was expected to be 18.7 million kilowatt hours (kWh). But according to recent energy bills, actual usage for the first year of operation, ending in December, was 31 million kWh, a usage overrunmore » that has cost the state of Illinois an extra $500,000. Some industry sources blame the thermal storage system and the electric heat system, which were untried when proposed in 1980, for much of the overrun, while others blame the building design.« less

ExoMol line lists - VII. The rotation-vibration spectrum of phosphine up to 1500 K

NASA Astrophysics Data System (ADS)

Sousa-Silva, Clara; Al-Refaie, Ahmed F.; Tennyson, Jonathan; Yurchenko, Sergei N.

2015-01-01

A comprehensive hot line list is calculated for 31PH3 in its ground electronic state. This line list, called SAlTY, contains almost 16.8 billion transitions between 7.5 million energy levels and it is suitable for simulating spectra up to temperatures of 1500 K. It covers wavelengths longer than 1 μm and includes all transitions to upper states with energies below hc × 18 000 cm-1 and rotational excitation up to J = 46. The line list is computed by variational solution of the Schrödinger equation for the rotation-vibration motion employing the nuclear-motion program TROVE. A previously reported ab initio dipole moment surface is used as well as an updated `spectroscopic' potential energy surface, obtained by refining an existing ab initio surface through least-squares fitting to the experimentally derived energies. Detailed comparisons with other available sources of phosphine transitions confirms SAlTY's accuracy and illustrates the incompleteness of previous experimental and theoretical compilations for temperatures above 300 K. Atmospheric models are expected to severely underestimate the abundance of phosphine in disequilibrium environments, and it is predicted that phosphine will be detectable in the upper troposphere of many substellar objects. This list is suitable for modelling atmospheres of many astrophysical environments, namely carbon stars, Y dwarfs, T dwarfs, hot Jupiters and Solar system gas giant planets. It is available in full from the Strasbourg data centre, CDS, and at www.exomol.com.

Cyberchondriacs.

PubMed

Smith, Peter K; Fox, Adam T; Davies, Patrick; Hamidi-Manesh, Laila

2006-01-01

Over 110 million Americans have accessed the internet for healthcare information. This information is often used in medical consultations and possibly contributing to increasing health care burdens. Although well informed patients are an advantage in disease management, the quality and reliability of information online is variable. Adolescents today have grown up with the Internet as a primary knowledge source, but still lack the skills to effectively filter credible information. Voluntary standards on health information have been attempted by Health on the Net Foundation; however their success has been limited, mainly due to the fact that most people searching for health information on line use a search engine rather than a specific site. This makes regulations almost impossible. Cyberchondriacs, a term used to describe anyone who seeks health-related information on the Internet, are not only at risk of acquiring unreliable information on line and therefore potential unnecessary anxiety, but they could also be financially exploited, for example, by e-health organisations and pharmaceutical companies. Moreover, the vulnerable e-health seeker, such as the inexperienced adolescent, is able to buy any quantity of nearly any medication on-line. Reasons for patients seeking information on line are varied, but include not having enough time at consultations. To try to address these issues, organisations such as NHS direct have been set up but their success is difficult to measure due to a lack of data. However, potential exploitation of a vulnerable population and the motivations behind their search for information on the internet merit further study.

Do Vehicle Recalls Reduce the Number of Accidents? The Case of the U.S. Car Market

ERIC Educational Resources Information Center

Bae, Yong-Kyun; Benitez-Silva, Hugo

2011-01-01

The number of automobile recalls in the U.S. has increased sharply in the last two decades, and the numbers of units involved are often counted in the millions. In 2010 alone, over 20 million vehicles were recalled in the United States, and the massive recalls of full model lines by Toyota have brought this issue to the front pages around the…

Children in Poverty: Trends, Consequences, and Policy Options. Child Trends Research Brief, Publication #2009-11

ERIC Educational Resources Information Center

Moore, Kristin Anderson; Redd, Zakia; Burkhauser, Mary; Mbwana, Kassim; Collins, Ashleigh

2009-01-01

The number of U.S. children living in poverty increased in 2007--continuing an upward trend dating back to 2000: in 2007, 13.3 million children were living in poverty, up from 11.6 million children in 2000. The percentage of children living in families with incomes below the poverty line has increased from 16.2 percent in 2000 to 18.0 percent in…

Congress examines administration's coal research priorities

NASA Astrophysics Data System (ADS)

Showstack, Randy

2011-10-01

While the Obama administration has proposed a shift in coal research funding to further emphasize carbon capture and sequestration (CCS) programs in its fiscal year (FY) 2012 budget request, Republicans and several witnesses at a 13 October hearing of a subcommittee of the House of Representatives' Committee on Science, Space, and Technology questioned those priorities, called for additional federal funding for coal research, and defended the use of coal as a major part of the U.S. energy sector. The administration's FY 2012 budget requests 291.4 million to fund the Department of Energy's (DOE) CCS and power systems program while zeroing out funding for DOE's fuels and power systems program (which includes funding for coal research) and shifting some of its line items to the CCS program. The FY 2011 continuing resolution has funded the fuels and power systems program at 400.2 million, including 142 million for carbon sequestration, 64.8 million for innovations for existing plants, and funding for other subprograms such as advanced integrated gasification combined cycle (52.9 million), fuel cells (49.8 million), and advanced research ($47.6 million).

A life cycle carbon dioxide inventory of the Million Trees Los Angeles Program

Treesearch

E. Gregory McPherson; Alissa Kendall

2014-01-01

PurposeThis study seeks to answer the question, “Will the Million Trees LA (Million Trees Los Angeles, MTLA) program be a carbon dioxide (CO2) sink or source?” Because there has never been a full accounting of CO2 emissions, it is unclear if urban tree planting initiatives (TPIs) are likely to be...

40 CFR 421.306 - Pretreatment standards for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... average mg/kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.346 0.140 Lead 0.262 0.122... Maximum for monthly average mg/kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.385 0... for any 1 day Maximum for monthly average mg/kg (pounds per million pounds) of TiCl4 handled Chromium...

40 CFR 421.306 - Pretreatment standards for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... average mg/kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.346 0.140 Lead 0.262 0.122... Maximum for monthly average mg/kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.385 0... for any 1 day Maximum for monthly average mg/kg (pounds per million pounds) of TiCl4 handled Chromium...

40 CFR 421.306 - Pretreatment standards for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... average mg/kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.346 0.140 Lead 0.262 0.122... Maximum for monthly average mg/kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.385 0... for any 1 day Maximum for monthly average mg/kg (pounds per million pounds) of TiCl4 handled Chromium...

Chandra X-Ray Observatory Image of Andromeda Galaxy

NASA Technical Reports Server (NTRS)

1999-01-01

Chandra X-Ray Observatory took this first x-ray picture of the Andromeda Galaxy (M31) on October 13, 1999. The blue dot in the center of the image is a 'cool' million-degree x-ray source where a supermassive black hole with the mass of 30-million suns is located. The x-rays are produced by matter furneling toward the black hole. Numerous other hotter x-ray sources are also apparent. Most of these are probably due to x-ray binary systems, in which a neutron star or black hole is in close orbit around a normal star. While the gas falling into the central black hole is cool, it is only cool by comparison to the 100 other x-ray sources in the Andromeda Galaxy. To be detected by an x-ray telescope, the gas must have a temperature of more than a million degrees. The Andromeda Galaxy is our nearest neighbor spiral galaxy at a distance of two million light years. It is similar to our own Milky Way in size, shape, and also contains a supermassive black hole at the center. (Photo Credit: NASA/CXC/SAO/S. Murray, M. Garcia)

History of Chandra X-Ray Observatory

NASA Image and Video Library

1999-10-13

Chandra X-Ray Observatory took this first x-ray picture of the Andromeda Galaxy (M31) on October 13, 1999. The blue dot in the center of the image is a "cool" million-degree x-ray source where a supermassive black hole with the mass of 30-million suns is located. The x-rays are produced by matter furneling toward the black hole. Numerous other hotter x-ray sources are also apparent. Most of these are probably due to x-ray binary systems, in which a neutron star or black hole is in close orbit around a normal star. While the gas falling into the central black hole is cool, it is only cool by comparison to the 100 other x-ray sources in the Andromeda Galaxy. To be detected by an x-ray telescope, the gas must have a temperature of more than a million degrees. The Andromeda Galaxy is our nearest neighbor spiral galaxy at a distance of two million light years. It is similar to our own Milky Way in size, shape, and also contains a supermassive black hole at the center. (Photo Credit: NASA/CXC/SAO/S. Murray, M. Garcia)

Test Analysis Tools to Ensure Higher Quality of On-Board Real Time Software for Space Applications

NASA Astrophysics Data System (ADS)

Boudillet, O.; Mescam, J.-C.; Dalemagne, D.

2008-08-01

EADS Astrium Space Transportation, in its Les Mureaux premises, is responsible for the French M51 nuclear deterrent missile onboard SW. There was also developed over 1 million of line of code, mostly in ADA, for the Automated Transfer Vehicle (ATV) onboard SW and the flight control SW of the ARIANE5 launcher which has put it into orbit. As part of the ATV SW, ASTRIUM ST has developed the first Category A SW ever qualified for a European space application. To ensure that all these embedded SW have been developed with the highest quality and reliability level, specific development tools have been designed to cover the steps of source code verification, automated validation test or complete target instruction coverage verification. Three of such dedicated tools are presented here.

An accreting black hole model for Sagittarius A

NASA Technical Reports Server (NTRS)

Melia, Fulvio

1992-01-01

Several observations, notably of broad He I, Br-alpha, and Br-gamma emission lines from the vicinity of IRS 16, indicate the presence of a strong circumnuclear wind near the dynamical center of the Galaxy. Sgr A, a hypothesized supermassive object situated about 0.06 pc to the west of IRS 16, should be accreting from this wind if it is not itself a source of gaseous outflow, for which there is currently no observational evidence. Here, the spectrum and flux of radiation resulting from this process are calculated, and it is shown that they are consistent with the data over at least 12 decades of frequency. Together with the kinematic studies of the stellar and gas distributions in this region, the model argues strongly in favor of Sgr A being a black hole with mass over a million solar masses.

Transient behavior of a flare-associated solar wind. I - Gas dynamics in a radial open field region

NASA Technical Reports Server (NTRS)

Nagai, F.

1984-01-01

A numerical investigation is conducted into the way in which a solar wind model initially satisfying both steady state and energy balance conditions is disturbed and deformed, under the assumption of heating that correspoonds to the energy release of solar flares of an importance value of approximately 1 which occur in radial open field regions. Flare-associated solar wind transient behavior is modeled for 1-8 solar radii. The coronal temperature around the heat source region rises, and a large thermal conductive flux flows inward to the chromosphere and outward to interplanetary space along field lines. The speed of the front of expanding chromospheric material generated by the impingement of the conduction front on the upper chromosphere exceeds the local sound velocity in a few minutes and eventually exceeds 100 million cm/sec.

Sawmill closures, openings, and net capacity changes in the softwood lumber sector, 1996-2003 [electronic resource

Treesearch

Henry Spelter

From a starting universe of approximately 1,300 Canadian and American sawmills, 149 were permanently closed between 1996 and 2003. This figure does not include small portable or part-time operations. These mills represented 17.6 million m3 of capacity, nearly 12% of the 1995 industry total. On the other hand, 25 new mills brought on-line have offset 4.9 million m3 of...

Million Degree Plasmas in Extreme Ultraviolet (EUV) Astrophysics. White Paper in Response to Astro2010 Science Call

DTIC Science & Technology

2010-01-01

photometry , timing measurements of suitable cadence, and advanced theory are the keys to understanding the physics of million degree plasmas in...Disentangling these components requires time - and phase- resolved spectroscopic observations of a sample that spans a range of mass accretion rates...many narrow lines, or a continuum with strong, broad absorption features. Key Objective: Obtaining time - and phase- resolved high-resolution EUV

Plant operation planning and scheduling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jammar, R.J.

When properly designed, planning and scheduling can actually add millions of dollars per year to the bottom line. Planning and scheduling is a continuum of decisions starting with crude selection and ending with establishing short-term targets for crude processing and blending. It also includes maintaining optimization and operation simulation models. It is thought that conservatively, a refinery may save from $5 million to $10 million a year if it pays more attention to the processes behind proper planning and scheduling. Of course, the amount of savings can reach staggering proportions for companies now at the bottom of the Solomon Associatesmore » Inc. refinery performance ranking.« less

Kyrgyzstan: Recent Developments and U.S. Interests

DTIC Science & Technology

2010-09-09

industries , housing, and retail outlets. Kyrgyzstan has surplus hydroelectric energy, rare earth mineral reserves, and tourism potential that could...party in Frunze (now Bishkek). In the late 1980s, she served as head of the Soviet delegation to UNESCO, and later as Soviet ambassador to Malaysia ...164 million in 2010, $120 million in 2011, and $66 million in 2012).16 Gold production has been the most significant industrial source of GDP and

United States Air Force 611th Civil Engineer Squadron, Elmendorf, AFB, Alaska. Final engineering evaluation/cost analysis, million gallon hill source area of the West Unit, Galena Airport, Alaska

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-02-05

This decision document presents the selected removal action for the Million Gallon Hill source area of the Installation Restoration Program (IRP) site ST009, otherwise known as the West Unit at Galena Airport, Alaska. The information from the RI Report is summarized, along with an analysis of potential removal action alternatives in the Engineering Evaluation/Cost Analysis (EE/CA).

Assessing dissolved inorganic nitrogen flux in the Yangtze River, China: Sources and scenarios

NASA Astrophysics Data System (ADS)

Xu, Hao; Chen, Zhongyuan; Finlayson, Brian; Webber, Michael; Wu, Xiaodan; Li, Maotian; Chen, Jing; Wei, Taoyuan; Barnett, Jon; Wang, Mark

2013-07-01

This study gives a thorough assessment of the occurrences of dissolved inorganic nitrogen (DIN) in the Yangtze River in the past half century. The results have shown that nitrogen fertilizer, a major DIN source, has been replaced by domestic sewage in the last decade, which has dramatically driven up DIN loads in the Yangtze. DIN concentrations showed a rapid increase from < 0.5 mg L- 1 in the 1960s to nearly 1.5 mg L- 1 at the end of the 1990s. Since then DIN has remained steady at ca. 1.6-1.8 mg L- 1. A significant relationship between the historical DIN record at the downstream gauging station (Datong) and nitrogen (N) sources in the Yangtze River basin is established using principal components analysis. This allows us to apportion DIN loads for the year 2007 (the most recent year of measured DIN data available) to various N sources, listed here in order of weight: sewage (0.391 million tons); atmosphere (0.358 million tons); manure (0.318 million tons), N-fertilizer (0.271 million tons). Therefore, we estimated that a DIN load of 1.339 × 106 t was delivered to the lower Yangtze and its estuarine water in that year. We established scenarios to predict DIN concentrations in the lower Yangtze at 10 year intervals to 2050. For a dry year (20,000 m3 s- 1) DIN concentrations would range from 2.2-3.0 mg L- 1 for 2020-2050. This far exceeds the 2.0 mg L- 1 defined on the Chinese National Scale as the worst class for potable source water. The scenario results suggest that upgrading the sewage treatment systems throughout the basin will be an effective way to help reduce DIN concentrations to less than 2.0 mg L- 1 in the lower Yangtze. This would save the Shanghai megacity from the increasing threat of heavily polluted water sources, where > 23 million people are at present dependent on the Yangtze estuary for 70% of their freshwater intake.

Estimated water use in Puerto Rico, 1995

USGS Publications Warehouse

Molina-Rivera, Wanda L.

1998-01-01

Water-use data during calendar year 1995 was compiled for the 78 municipios of the Commonwealth of Puerto Rico. Eight offstream water-use categories were considered during the study: public supply, wastewater treatment discharges, domestic, industrial, mining, thermoelectric power, livestock, and irrigation. Three instream water-use categories were considered: hydroelectric power, saline water used at thermoelectric power plants, and reservoir evaporation. Freshwater withdrawals for offstream use from surface- and ground-water sources in Puerto Rico were estimated to be 566 million gallons per day. The largest amount of freshwater withdrawn was 431 million gallons per day for public supply. Total discharge from public wastewater treatment facilities was reported as 185 million gallons per day. Fresh surface- and ground-water withdrawals for domestic and industrial self-supplied facilities were estimated to be about 19 million gallons per day. Mining activities, which in Puerto Rico are mostly limited to the production of sand and gravel, withdrew about 4.2 million gallons per day of freshwater. Livestock activities used 6.3 million gallons per day from surface- and ground-water sources to meet the water needs of the 12.1 million animals counted in the 1992 Census of Agriculture in Puerto Rico. Self-supplied ground-water withdrawals for thermoelectric facilities were estimated to be 2.2 million gallons per day. Freshwater withdrawals for irrigation purposes were estimated to be 103 million gallons per day, or approximately 18 percent of all offstream freshwater withdrawals. Instream freshwater withdrawals by hydroelectric facilities were 349 million gallons per day. Reservoir evaporation is considered to be a consumptive use associated with the storage of water. The evaporation from 15 reservoirs in Puerto Rico was estimated to average about 23,900 acre-feet from a total reservoir surface area of 6,900 acres. The largest amount of withdrawals was 2,260 million gallons per day of saline water (instream use) for thermoelectric power.

A Selective Stratistical Study of Transaction Activity in a Large On-Line Automated Circulation System. Final Report.

ERIC Educational Resources Information Center

Guthrie, Gerry D.

The objective of this study was to provide the library community with basic statistical data from on-line activity in the Ohio State University Libraries' Circulation System. Over 1.6 million archive records in the circulation system for 1972 were investigated to produce subject reports of circulation activity, activity reports by collection…

In vitro fertilization and stem cell harvesting from human embryos: the law and practice in the United States.

PubMed

Hook, C Christopher

2010-07-01

The challenges before science and medicine are these: science must explore the natural world as thoroughly as possible, while still honoring, protecting, serving and preserving the subject of its investigations, and the human beings for whom it is a tool; medicine must confront disease and disability as effectively as possible, while also honoring, protecting, and preserving those beings for whom it serves - all of those beings, not just some, or even most, at the potential expense of others. These goals are challenged by embryo-destructive human embryonic stem cell research. The human embryo is a human being as clearly defined by embryology, and as such should be protected by the codes governing human subject research. However, because of the "potential" benefits offered by pluripotent stem cells, coupled with abortion politics and a very poorly regulated infertility industry, United States governmental advisory commissions and the scientific, medical, and political communities have attempted to define away the humanity of the human embryo, with a few notable exceptions. Because infertility treatments in the United States are poorly regulated, there are large numbers of supernumerary embryos in cryopreservation. However, only a tiny portion of these will ever be potentially available for research, and thus are not a realistic source of the cells necessary to provide treatments to the millions who might benefit from proposed stem cell based therapies. Cloning will not be the answer either, given the millions of women who must be exploited to provide sufficient numbers of eggs to generate the cloned cell lines. Moreover, the disposition decisions parents must make for their extra embryos are often agonizing, and not uncommonly change. The use of supernumerary embryos as a source for human embryonic stem cells is unethical, will never be a sufficient source for the medical treatments expected from stem cell research, and is often a source of great distress for the conceiving parents. The United States experience is not a positive model for other countries to emulate.

Artifact Removal from Biosignal using Fixed Point ICA Algorithm for Pre-processing in Biometric Recognition

NASA Astrophysics Data System (ADS)

Mishra, Puneet; Singla, Sunil Kumar

2013-01-01

In the modern world of automation, biological signals, especially Electroencephalogram (EEG) and Electrocardiogram (ECG), are gaining wide attention as a source of biometric information. Earlier studies have shown that EEG and ECG show versatility with individuals and every individual has distinct EEG and ECG spectrum. EEG (which can be recorded from the scalp due to the effect of millions of neurons) may contain noise signals such as eye blink, eye movement, muscular movement, line noise, etc. Similarly, ECG may contain artifact like line noise, tremor artifacts, baseline wandering, etc. These noise signals are required to be separated from the EEG and ECG signals to obtain the accurate results. This paper proposes a technique for the removal of eye blink artifact from EEG and ECG signal using fixed point or FastICA algorithm of Independent Component Analysis (ICA). For validation, FastICA algorithm has been applied to synthetic signal prepared by adding random noise to the Electrocardiogram (ECG) signal. FastICA algorithm separates the signal into two independent components, i.e. ECG pure and artifact signal. Similarly, the same algorithm has been applied to remove the artifacts (Electrooculogram or eye blink) from the EEG signal.

Alkali Halide Opacity in Brown Dwarf and Cool Stellar Atmospheres: A Study of Lithium Chloride

NASA Astrophysics Data System (ADS)

Kirby, K.; Weck, P. F.; Schweitzer, A.; Stancil, P. C.; Hauschildt, P. H.

2003-12-01

Recent thermochemical equilibrium calculations have revealed the important role played by lithium chloride in the lithium chemistry of cool dwarf atmospheres (K. Lodders 1999, ApJ 519, 793). Indeed, LiCl appears to be the dominant Li-bearing gas over an extended domain of the (P,T) diagram, typically for temperatures below 1500 K. LiCl has a large dipole moment in its ground electronic state which can give rise to intense rovibrational line spectra. In addition, LiCl can make dipole transitions to several low-lying unbound excited states, causing dissociation of the molecule. For these reasons, LiCl may be a significant source of line and continuum opacity in brown dwarf and cool stellar atmospheres. In this work, we report calculations of complete lists of line oscillator strengths and photodissociation cross sections for the low-lying electronic states of LiCl. We have performed single- and double-excitation configuration interaction calculations using the ALCHEMY ab initio package (Mc Lean et al. 1991, MOTECC 91, Elsevier, Leiden) and obtained the potential curves and the corresponding dipole transition moment functions between the X 1Σ ^+ ground state and the B 1Σ ^+ and A 1Π excited states. The resulting line oscillator strengths and molecular photodissociation cross sections have been included in the PHOENIX stellar atmosphere code (Hauschildt & Baron 1999, J. Comput. App. Math. 102, 41). The new models, calculated using spherical geometry for all gravities considered, also incorporate our latest database of nearly 670 million molecular lines, and updated equations of state (EOS). This work was supported in part by NSF grants AST-9720704 and AST-0086246, NASA grants NAG5-8425, NAG5-9222, and NAG5-10551 as well as NASA/JPL grant 961582.

Public funding for contraceptive, sterilization and abortion services, 1994.

PubMed

Sollom, T; Gold, R B; Saul, R

1996-01-01

In 1994, federal and state funding for contraceptive services and supplies reached +715 million. Funding totaled +148 million for contraceptive sterilization and +90 million for abortion services. According to a survey of state health, Medicaid and social service agencies, reported spending on contraceptive services and supplies increased by 11% between 1992 and 1994. In the same period, spending under Title X rose by 37%, making it the third largest public funding source for contraceptive services and supplies. The largest source of public funds for family planning services continues to be the joint federal-state Medicaid program. Medicaid family planning expenditures increased by only 4% between 1992 and 1994, a sizable decrease in growth from previous years. State funds continue to be the second largest source, providing almost one-quarter of reported public expenditures in 1994. The maternal and child health and social services block grants remain relatively minor sources of support nationally, although in a handful of states they provide the majority of public-sector funds. State governments were virtually the sole source of public support for the 203,200 abortions provided in 1994 to low-income women. Despite the loosening of federal abortion funding criteria in FY 1994 permitting payment in cases of rape and incest, federally funded abortions numbered only 282.

Overcoming CRPC Treatment Resistance via Novel Dual AKR1C3 Targeting

DTIC Science & Technology

2017-10-01

We therefore characterized another drug resistant line from C4-2B cells, C4-2B AbiR cells. C4-2B AbiR cells were resistant to Abi acetate in a...Testosterone level in C4-2B AbiR cell was 12 pg/50 million cells, similar to that in C4-2B MDVR or LNCaP-AKR1C3 cells. With the single drug resistant...cell lines on hand, we tested for their cross- resistance to Enza and Abi. While the parental line was sensitive to both drugs , the resistant lines

Estimated Water Use in 1990, Island of Kauai, Hawaii

USGS Publications Warehouse

Shade, Patricia J.

1995-01-01

The estimated total quantity of freshwater withdrawn on the island of Kauai, Hawaii, in 1990 was 370.84 million gallons per day of which 46.29 million gallons per day (12 percent) was from ground-water sources, and 324.55 million gallons per day (88 percent) was from surface-water sources. An additional estimated 40.94 million gallons per day of saline water was withdrawn for thermoelectric power generation. Agricultural irrigation was the principal use, accounting for 66 percent of the total freshwater withdrawals. Irrigation accounted for about 40 percent of the fresh ground-water withdrawals, followed by public supply, thermoelectric power generation, self-supplied domestic, self-supplied commercial, and self-supplied industrial withdrawals. Agricultural irrigation accounted for 69 percent of the total fresh surface-water withdrawals, followed by hydroelectric power generation, self-supplied industrial, public-supply and self-supplied livestock withdrawals. A comparison of water-use data for 1980 and 1990 shows total freshwater uses decreased during 1990 by slightly more than 100 million gallons per day because of decreased withdrawals for sugarcane irrigation and processing. During this time, increased domestic, commercial, and thermoelectric power usage reflects increases in the resident population and in tourism on the island.

Review of US medical school finances, 1997-1998.

PubMed

Krakower, J Y; Williams, D J; Jones, R F

1999-09-01

Based on data from the Annual Medical School Questionnaire of the Liaison Committee on Medical Education (LCME), to which 100% of schools responded, we found that revenue supporting programs and activities of the 125 accredited medical schools in the United States totaled $36997 million in 1997-1998. A large proportion of revenue (79%) was derived from 3 sources: practice plans ($12559 million; 33.9%), grants and contracts ($10916 million; 29.5%), and hospital support ($5741 million; 15.5%). An analysis of revenue trends revealed that medical schools, in aggregate, have continued to experience growth during the last 2 years. However, the aggregate numbers mask considerable variation among schools with regard to changes in financing. Between 1995-1996 and 1996-1997, 46 schools (37%) reported constant-dollar declines in the sum of practice plan and hospital revenue, and 50 schools (40%) reported a decline from 1996-1997 to 1997-1998. The financial data reviewed in this report demonstrate the continued dependence of medical schools on faculty-generated sources of revenue and confirm the perception that a growing number of medical schools are experiencing reductions in key sources of financial support. Current and projected reductions in teaching hospital revenue due to the implementation of the Balanced Budget Amendment are expected to erode further hospital support for medical school programs and activities.

40 CFR 49.129 - Rule for limiting emissions of sulfur dioxide.

Code of Federal Regulations, 2010 CFR

2010-07-01

... emissions from a combustion source stack must not exceed an average of 500 parts per million by volume, on a..., air pollution source, ambient air, British thermal unit (Btu), coal, combustion source, continuous..., incinerator, marine vessel, mobile sources, motor vehicle, nonroad engine, nonroad vehicle, open burning...

40 CFR 49.129 - Rule for limiting emissions of sulfur dioxide.

Code of Federal Regulations, 2011 CFR

2011-07-01

... emissions from a combustion source stack must not exceed an average of 500 parts per million by volume, on a..., air pollution source, ambient air, British thermal unit (Btu), coal, combustion source, continuous..., incinerator, marine vessel, mobile sources, motor vehicle, nonroad engine, nonroad vehicle, open burning...

Selected coal-related ground-water data, Wasatch Plateau-Book Cliffs area, Utah

USGS Publications Warehouse

Sumsion, C.T.

1979-01-01

The Wasatch Plateau-Book Cliffs%area as used in this report consists of about 8,000 square miles in east-central Utah. The major geographic features included in the area are the Wasatch Plateau, Book Cliffs, San Rafael Swell, Price River basin, and a small part of the Green River basin (pl. 1). The area is defined by approximate drainage-divide boundaries in the Wasatch Plateau and Book Cliffs, by an arbitrary boundary on the south, and by the Utah-Colorado State line on the east.The Wasatch Plateau-Book Cliffs area includes all the operating coal mines in Utah in 1978. Annual coal production in the area is expected to increase from the current (1978) rate of about 8 million tons to as much as 30 million tons within the next 10 years (J. W. Moffitt, U.S. Geological Survey, oral commun., 1978). Ground water is an important source of water supply in the area. As mining increases and mining-related municipalities grow, many sources of ground-water supply may be subjected to increased demands and possibly degradation of chemical quality.Waddell, Vickers, Upton, and Contratto (1978) reported some ground- water data after a reconnaissance of part of the area. The purpose of this report, which was prepared in cooperation with the U.S. Bureau of Land Management, is to present a more detailed compilation of ground-water-related data that were collected and compiled during October 1976 to March 1978. The report is designed to make the data available in an orderly and usable form for local and regional water managers and other users of water data.

Biofortification of essential nutritional compounds and trace elements in rice and cassava.

PubMed

Sautter, C; Poletti, S; Zhang, P; Gruissem, W

2006-05-01

Plant biotechnology can make important contributions to food security and nutritional improvement. For example, the development of 'Golden Rice' by Professor Ingo Potrykus was a milestone in the application of gene technology to deliver both increased nutritional qualities and health improvement to wide sections of the human population. Mineral nutrient and protein deficiency as well as food security remain the most important challenges for developing countries. Current projects are addressing these issues in two major staple crops, cassava (Manihot esculenta Crantz) and rice. The tropical root crop cassava is a major source of food for approximately 600 million of the population worldwide. In sub-Saharan Africa >200 million of the population rely on cassava as their major source of dietary energy. The nutritional quality of the cassava root is not sufficient to meet all dietary needs. Rice is the staple food for half the world population, providing approximately 20% of the per capita energy and 13% of the protein for human consumption worldwide. In many developing countries the dietary contributions of rice are substantially greater (29.3% dietary energy and 29.1% dietary protein). The current six most popular 'mega' rice varieties (in terms of popularity and acreage), including Chinese hybrid rice, have an incomplete amino acid profile and contain limited amounts of essential micronutrients. Rice lines with improved Fe contents have been developed using genes that have functions in Fe absorption, translocation and accumulation in the plant, as well as improved Fe bioavailability in the human intestine. Current developments in biotechnology-assisted plant improvement are reviewed and the potential of the technology in addressing human nutrition and health are discussed.

VizieR Online Data Catalog: Gaia DR2 (Gaia Collaboration, 2018)

NASA Astrophysics Data System (ADS)

Gaia Collaboration

2018-04-01

Contents of Gaia DR2: The five-parameter astrometric solution - positions on the sky (alpha,delta), parallaxes, and proper motions - for more than 1.3 billion (109) sources, with a limiting magnitude of G=21 and a bright limit of G~=3. Parallax uncertainties are in the range of up to 0.04 milliarcsecond for sources at G<15, around 0.1mas for sources with G=17 and at the faint end, the uncertainty is of the order of 0.7mas at G=20. The corresponding uncertainties in the respective proper motion components are up to 0.06mas/yr (for G<15mag), 0.2mas/yr (for G=17mag) and 1.2mas/yr (for G=20mag). The Gaia DR2 parallaxes and proper motions are based only on Gaia data; they do no longer depend on the Tycho-2 Catalogue. Median radial velocities (i.e. the median value over the epochs) for more than 6 million stars with a mean G magnitude between about 4 and 13 and an effective temperature (Teff) in the range of about 3550 to 6900K. This leads to a full six-parameter solution: positions and motions on the sky with parallaxes and radial velocities, all combined with mean G magnitudes. The overall precision of the radial velocities at the bright end is in the order of 200-300m/s while at the faint end the overall precision is approximately 1.2km/s for a Teff of 4750K and about 2.5km/s for a Teff of 6500K. An additional set of more than 200 million sources for which a two-parameter solution is available: the positions on the sky (alpha,delta) combined with the mean G magnitude. These sources will have a positional uncertainty at G=20 of about 2mas, at J2015.5. G magnitudes for more than 1.5 billion sources, with precisions varying from around 1 milli-mag at the bright (G<13) end to around 20 milli-mag at G=20. Please be aware that the photometric system for the G band in Gaia DR2 will be different from the photometric system as used in Gaia DR1. GBP and GRP magnitudes for more than 1.1 billion sources, with precisions varying from a few milli-mag at the bright (G<13) end to around 200 milli-mag at G=20. Full passband definitions for G, BP and RP. These passbands are now available for download. A detailed description is given here. Epoch astrometry for more than 13,000 known asteroids based on more than 1.5 million CCD observations. 96% of the along-scan (AL) residuals are in the range -5 to 5mas, and 52% of the AL residuals are in the range of -1 to 1mas. The observations will be published in Gaia DR2 and also delivered to the Minor Planet Center (MPC). Subject to limitations the effective temperatures Teff for more than 150 million sources brighter than 17th magnitude with effective temperatures in the range 3000 to 10,000 K. For a subset of these sources also the line-of-sight extinction AG and reddening E(BP-RP) will be given, as well as the luminosity and radius. Lightcurves for more than 500,000 variable sources consisting of Cepheids, RR Lyrae, Mira and Semi-Regular Candidates as well as High-Amplitude Delta Scuti, BY Draconis candidates, SX Phoenicis Candidates and short time scale phenomena. Planned cross-matches between Gaia DR2 sources on the one hand and Hipparcos-2, Tycho-2, 2MASS PSC, SDSS DR9, Pan-STARRS1, GSC2.3, PPM-XL, AllWISE, and URAT-1 data on the other hand. Catalogue of radial velocity standard stars (Soubiran et al., 2018A&A..in.prep...): Individual and combined radial velocity measurements are presented for 4813 stars in rvstdcat.dat and rvstdmes.dat files. (20 data files).

Assessment of Sociodemographic and Geographic Disparities in Cancer Risk from Air Toxics in South Carolina

PubMed Central

Wilson, Sacoby; Burwell-Naney, Kristen; Jiang, Chengsheng; Zhang, Hongmei; Samantapudi, Ashok; Murray, Rianna; Dalemarre, Laura; Rice, LaShanta; Williams, Edith

2015-01-01

Populations of color and low-income communities are often disproportionately burdened by exposures to various environmental contaminants, including air pollution. Some air pollutants have carcinogenic properties that are particularly problematic in South Carolina (SC), a state that consistently has high rates of cancer mortality for all sites. The purpose of this study was to assess cancer risk disparities in SC by linking risk estimates from the U.S. Environmental Protection Agency’s 2005 National Air Toxics Assessment (NATA) with sociodemographic data from the 2000 US Census Bureau. Specifically, NATA risk data for varying risk categories were linked by tract ID and analyzed with sociodemographic variables from the 2000 census using R. The average change in cancer risk from all sources by sociodemographic variable was quantified using multiple linear regression models. Spatial methods were further employed using ArcGIS 10 to assess the distribution of all source risk and percent non-white at each census tract level. The relative risk estimates of the proportion of high cancer risk tracts (defined as the top 10% of cancer risk in SC) and their respective 95% confidence intervals (CIs) were calculated between the first and latter three quartiles defined by sociodemographic factors, while the variance in the percentage of high cancer risk between quartile groups was tested using Pearson’s chi-square. The average total cancer risk for SC was 26.8 people/million (ppl/million). The risk from on-road sources was approximately 5.8 ppl/million, higher than the risk from major, area, and non-road sources (1.8, 2.6, and 1.3 ppl/million), respectively. Based on our findings, addressing on-road sources may decrease the disproportionate cancer risk burden among low-income populations and communities of color in SC. PMID:26037107

Ground water resources of the Bryce Canyon National Park Area, Utah: With a section on the drilling of a test well

USGS Publications Warehouse

Marine, I. Wendell

1963-01-01

The water need at Bryce Canyon National Park in 1957 was about 1.3 million cubic feet for a tourist season that lasted from the middle of May to the middle of October. To evaluate the adequacy of water-supply sources, a hypothetical future need of 5 million cubic feet of water per season is used. This amount of water might be obtained from the East Fork of the Sevier River, from wells in the alluvium of the East Fork, from Yellow Creek Spring and nearby springs, which are below the canyon rim, or from a well drilled about 2,000 feet to the top of the Tropic shale. Although the present source of water, consisting of wells in the alluvium of East Creek valley, may be an important supplemental source in the future, it will not yield sufficient water in dry years to meet the total demand for water at the park.The yield of Yellow Creek Spring and nearby springs is estimated at a total of 7.8 million cubic feet of water per season. The springs provide water of satisfactory chemical quality, and are a reliable source even in times of drought. A serious disadvantage of using this source of water is the difficulty of constructing a pipeline over extremely rugged terrain from the source to the lodge and headquarters area.A well drilled to the top of the Tropic shale of Cretaceous age in the lodge and headquarters area might penetrate two or more aquifers, one at the base of the Wasatch formation of Eocene age and one or more in the Wahweap and Straight Cliffs sandstones of Cretaceous age. The yield of this well would depend to a large degree on the number of fractures encountered. To assure the most favorable conditions for intercepting fracture zones in the bedrock, a test-well site is proposed near the crest of a gentle anticline where tension fractures in the rocks should be common.Shallow wells in the alluvium of East Creek valley cannot be depended upon to yield sufficient water in times of drought, but they are nevertheless an important source. The water-storage capacity of the alluvium of East Creek valley in the vicinity of the wells of the Utah Parks Co. is estimated at 1.4 million cubic feet. By lowering the water table in the valley uniformly without creating excessively large cones of depression, the alluvium could supply the 1.3 million cubic feet of water per season estimated as the water need in 1957. However, in times of drought this alluvium cannot supply the hypothetical future needs of 5 million cubic feet of water per season.

40 CFR 467.24 - New source performance standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions...

40 CFR 467.24 - New source performance standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions...

40 CFR 467.24 - New source performance standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions...

KECK SPECTROSCOPY OF FAINT 3 < z < 8 LYMAN BREAK GALAXIES: EVIDENCE FOR A DECLINING FRACTION OF EMISSION LINE SOURCES IN THE REDSHIFT RANGE 6 < z < 8

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schenker, Matthew A.; Ellis, Richard S.; Robertson, Brant E.

2012-01-10

Using deep Keck spectroscopy of Lyman break galaxies selected from infrared imaging data taken with the Wide Field Camera 3 on board the Hubble Space Telescope, we present new evidence for a reversal in the redshift-dependent fraction of star-forming galaxies with detectable Lyman alpha (Ly{alpha}) emission in the redshift range 6.3 < z < 8.8. Our earlier surveys with the DEIMOS spectrograph demonstrated a significant increase with redshift in the fraction of line emitting galaxies over the interval 4 < z < 6, particularly for intrinsically faint systems which dominate the luminosity density. Using the longer wavelength sensitivities of Lowmore » Resolution Imaging Spectrometer and NIRSPEC, we have targeted 19 Lyman break galaxies selected using recent WFC3/IR data whose photometric redshifts are in the range 6.3 < z < 8.8 and which span a wide range of intrinsic luminosities. Our spectroscopic exposures typically reach a 5{sigma} sensitivity of <50 A for the rest-frame equivalent width (EW) of Ly{alpha} emission. Despite the high fraction of emitters seen only a few hundred million years later, we find only two convincing and one possible line emitter in our more distant sample. Combining with published data on a further seven sources obtained using FORS2 on the ESO Very Large Telescope, and assuming continuity in the trends found at lower redshift, we discuss the significance of this apparent reversal in the redshift-dependent Ly{alpha} fraction in the context of our range in continuum luminosity. Assuming all the targeted sources are at their photometric redshift and our assumptions about the Ly{alpha} EW distribution are correct, we would expect to find so few emitters in less than 1% of the realizations drawn from our lower redshift samples. Our new results provide further support for the suggestion that, at the redshifts now being probed spectroscopically, we are entering the era where the intergalactic medium is partially neutral. With the arrival of more sensitive multi-slit infrared spectrographs, the prospects for improving the statistical validity of this result are promising.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mills, Evan; Jones, Richard B.

Large yet infrequent disruptions of electrical power can impact tens of millions of people in a single event, triggering significant economic damages, portions of which are insured. Small and frequent events are also significant in the aggregate. This article explores the role that insurance claims data can play in better defining the broader economic impacts of grid disruptions in the U.S. context. We developed four case studies, using previously unpublished data for specific actual grid disruptions. The cases include the 1977 New York City blackout, the 2003 Northeast blackout, multi-year national annual lightning-related electrical damage and multi-year national line-disturbance events.more » Insured losses represent between 3 and 64 per cent of total loss costs across the case studies. Here, the household sector emerges as a larger locus of costs than indicated in previous studies, and short-lived events emerge as important sources of loss costs.« less

Global GIS database; digital atlas of Central and South America

USGS Publications Warehouse

Hearn,, Paul P.; Hare, T.; Schruben, P.; Sherrill, D.; LaMar, C.; Tsushima, P.

2000-01-01

This CD-ROM contains a digital atlas of the countries of Central and South America. This atlas is part of a global database compiled from USGS and other data sources at the nominal scale of 1:1 million and is intended to be used as a regional-scale reference and analytical tool by government officials, researchers, the private sector, and the general public. The atlas includes free GIS software or may also be used with ESRI's ArcView software. Customized ArcView tools, specifically designed to make the atlas easier to use, are also included. The atlas contains the following datasets: country political boundaries, digital shaded relief map, elevation, slope, hydrology, locations of cities and towns, airfields, roads, railroads, utility lines, population density, geology, ecological regions, historical seismicity, volcanoes, ore deposits, oil and gas fields, climate data, landcover, vegetation index, and lights at night.

Anti-inflammatory agents from plants: progress and potential.

PubMed

Recio, M C; Andujar, I; Rios, J L

2012-01-01

The identification of substances that can promote the resolution of inflammation in a way that is homeostatic, modulatory, efficient, and well-tolerated by the body is of fundamental importance. Traditional medicines have long provided front-line pharmacotherapy for many millions of people worldwide. Medicinal extracts are a rich source of therapeutic leads for the pharmaceutical industry. The use of medicinal plant therapies to treat chronic illness, including rheumatoid arthritis (RA) and inflammatory bowel disease (IBD), is thus widespread and on the rise.The aim of this review is to present recent progress in clinical anti-inflammatory studies of plant extracts and compound leads such as green tea polyphenols, curcumin, resveratrol, boswellic acid, and cucurbitacins, among others, against chronic inflammatory diseases, mainly RA and IBD. In this context, the present paper also highlights the most promising experimental data on those plant extracts and pure compounds active in animal models of the aforementioned diseases.

An insurance perspective on U.S. electric grid disruption costs

DOE PAGES

Mills, Evan; Jones, Richard B.

2016-10-12

Large yet infrequent disruptions of electrical power can impact tens of millions of people in a single event, triggering significant economic damages, portions of which are insured. Small and frequent events are also significant in the aggregate. This article explores the role that insurance claims data can play in better defining the broader economic impacts of grid disruptions in the U.S. context. We developed four case studies, using previously unpublished data for specific actual grid disruptions. The cases include the 1977 New York City blackout, the 2003 Northeast blackout, multi-year national annual lightning-related electrical damage and multi-year national line-disturbance events.more » Insured losses represent between 3 and 64 per cent of total loss costs across the case studies. Here, the household sector emerges as a larger locus of costs than indicated in previous studies, and short-lived events emerge as important sources of loss costs.« less

Troubleshooting Costs

NASA Astrophysics Data System (ADS)

Kornacki, Jeffrey L.

Seventy-six million cases of foodborne disease occur each year in the United States alone. Medical and lost productivity costs of the most common pathogens are estimated to be 5.6-9.4 billion. Product recalls, whether from foodborne illness or spoilage, result in added costs to manufacturers in a variety of ways. These may include expenses associated with lawsuits from real or allegedly stricken individuals and lawsuits from shorted customers. Other costs include those associated with efforts involved in finding the source of the contamination and eliminating it and include time when lines are shut down and therefore non-productive, additional non-routine testing, consultant fees, time and personnel required to overhaul the entire food safety system, lost market share to competitors, and the cost associated with redesign of the factory and redesign or acquisition of more hygienic equipment. The cost associated with an effective quality assurance plan is well worth the effort to prevent the situations described.

Appalachian Regional Commission: 1981 Annual Report.

ERIC Educational Resources Information Center

Appalachian Regional Commission, Washington, DC.

Although fiscal year 1981 was a time of uncertainty for the Appalachian Regional Commission (ARC), Congress did appropriate $218.2 million for the highway program and $87 million for area development, research and local development districts (LDDs), and administrative costs. Coupled with other federal funds and funds from state and local sources,…

Research Advances. Image Pinpoints All 5 Million Atoms in Viral Coat; Bilirubin, "Animals-Only" Pigment, Found in Plants; New Evidence Shows Humans Make Salicylic Acid

NASA Astrophysics Data System (ADS)

King, Angela G.

2009-08-01

Recent "firsts" in chemical research: image of a viral capsid pinpointing 5 million atoms; isolation and identification of an "animal" pigment, bilirubin, from a plant source; evidence that humans make salicylic acid.

X-ray spectra of Hercules X-1. 1: Iron line fluorescence from a subrelativistic shell

NASA Technical Reports Server (NTRS)

Pravdo, S. H.; Becker, R. H.; Boldt, E. A.; Holt, S. S.; Serlemitsos, P. J.; Swank, J. H.

1977-01-01

The X-ray spectrum of Hercules X-1 was observed in the energy range 2-24 keV from August 29 to September 3, 1975. A broad iron line feature is observed in the normal high state spectrum. The line equivalent width is given along with its full-width-half-maximum energy. Iron line fluorescence from an opaque, cool shell of material at the Alfven surface provides the necessary luminosity in this feature. The line energy width can be due to Doppler broadening if the shell is forced to corotate with the pulsar at a radius 800 million cm. Implications of this model regarding physical conditions near Her X-1 are discussed.

A line-source method for aligning on-board and other pinhole SPECT systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yan, Susu; Bowsher, James; Yin, Fang-Fang

2013-12-15

Purpose: In order to achieve functional and molecular imaging as patients are in position for radiation therapy, a robotic multipinhole SPECT system is being developed. Alignment of the SPECT system—to the linear accelerator (LINAC) coordinate frame and to the coordinate frames of other on-board imaging systems such as cone-beam CT (CBCT)—is essential for target localization and image reconstruction. An alignment method that utilizes line sources and one pinhole projection is proposed and investigated to achieve this goal. Potentially, this method could also be applied to the calibration of the other pinhole SPECT systems.Methods: An alignment model consisting of multiple alignmentmore » parameters was developed which maps line sources in three-dimensional (3D) space to their two-dimensional (2D) projections on the SPECT detector. In a computer-simulation study, 3D coordinates of line-sources were defined in a reference room coordinate frame, such as the LINAC coordinate frame. Corresponding 2D line-source projections were generated by computer simulation that included SPECT blurring and noise effects. The Radon transform was utilized to detect angles (α) and offsets (ρ) of the line-source projections. Alignment parameters were then estimated by a nonlinear least squares method, based on the α and ρ values and the alignment model. Alignment performance was evaluated as a function of number of line sources, Radon transform accuracy, finite line-source width, intrinsic camera resolution, Poisson noise, and acquisition geometry. Experimental evaluations were performed using a physical line-source phantom and a pinhole-collimated gamma camera attached to a robot.Results: In computer-simulation studies, when there was no error in determining angles (α) and offsets (ρ) of the measured projections, six alignment parameters (three translational and three rotational) were estimated perfectly using three line sources. When angles (α) and offsets (ρ) were provided by the Radon transform, estimation accuracy was reduced. The estimation error was associated with rounding errors of Radon transform, finite line-source width, Poisson noise, number of line sources, intrinsic camera resolution, and detector acquisition geometry. Statistically, the estimation accuracy was significantly improved by using four line sources rather than three and by thinner line-source projections (obtained by better intrinsic detector resolution). With five line sources, median errors were 0.2 mm for the detector translations, 0.7 mm for the detector radius of rotation, and less than 0.5° for detector rotation, tilt, and twist. In experimental evaluations, average errors relative to a different, independent registration technique were about 1.8 mm for detector translations, 1.1 mm for the detector radius of rotation (ROR), 0.5° and 0.4° for detector rotation and tilt, respectively, and 1.2° for detector twist.Conclusions: Alignment parameters can be estimated using one pinhole projection of line sources. Alignment errors are largely associated with limited accuracy of the Radon transform in determining angles (α) and offsets (ρ) of the line-source projections. This alignment method may be important for multipinhole SPECT, where relative pinhole alignment may vary during rotation. For pinhole and multipinhole SPECT imaging on-board radiation therapy machines, the method could provide alignment of SPECT coordinates with those of CBCT and the LINAC.« less

A line-source method for aligning on-board and other pinhole SPECT systems

PubMed Central

Yan, Susu; Bowsher, James; Yin, Fang-Fang

2013-01-01

Purpose: In order to achieve functional and molecular imaging as patients are in position for radiation therapy, a robotic multipinhole SPECT system is being developed. Alignment of the SPECT system—to the linear accelerator (LINAC) coordinate frame and to the coordinate frames of other on-board imaging systems such as cone-beam CT (CBCT)—is essential for target localization and image reconstruction. An alignment method that utilizes line sources and one pinhole projection is proposed and investigated to achieve this goal. Potentially, this method could also be applied to the calibration of the other pinhole SPECT systems. Methods: An alignment model consisting of multiple alignment parameters was developed which maps line sources in three-dimensional (3D) space to their two-dimensional (2D) projections on the SPECT detector. In a computer-simulation study, 3D coordinates of line-sources were defined in a reference room coordinate frame, such as the LINAC coordinate frame. Corresponding 2D line-source projections were generated by computer simulation that included SPECT blurring and noise effects. The Radon transform was utilized to detect angles (α) and offsets (ρ) of the line-source projections. Alignment parameters were then estimated by a nonlinear least squares method, based on the α and ρ values and the alignment model. Alignment performance was evaluated as a function of number of line sources, Radon transform accuracy, finite line-source width, intrinsic camera resolution, Poisson noise, and acquisition geometry. Experimental evaluations were performed using a physical line-source phantom and a pinhole-collimated gamma camera attached to a robot. Results: In computer-simulation studies, when there was no error in determining angles (α) and offsets (ρ) of the measured projections, six alignment parameters (three translational and three rotational) were estimated perfectly using three line sources. When angles (α) and offsets (ρ) were provided by the Radon transform, estimation accuracy was reduced. The estimation error was associated with rounding errors of Radon transform, finite line-source width, Poisson noise, number of line sources, intrinsic camera resolution, and detector acquisition geometry. Statistically, the estimation accuracy was significantly improved by using four line sources rather than three and by thinner line-source projections (obtained by better intrinsic detector resolution). With five line sources, median errors were 0.2 mm for the detector translations, 0.7 mm for the detector radius of rotation, and less than 0.5° for detector rotation, tilt, and twist. In experimental evaluations, average errors relative to a different, independent registration technique were about 1.8 mm for detector translations, 1.1 mm for the detector radius of rotation (ROR), 0.5° and 0.4° for detector rotation and tilt, respectively, and 1.2° for detector twist. Conclusions: Alignment parameters can be estimated using one pinhole projection of line sources. Alignment errors are largely associated with limited accuracy of the Radon transform in determining angles (α) and offsets (ρ) of the line-source projections. This alignment method may be important for multipinhole SPECT, where relative pinhole alignment may vary during rotation. For pinhole and multipinhole SPECT imaging on-board radiation therapy machines, the method could provide alignment of SPECT coordinates with those of CBCT and the LINAC. PMID:24320537

A line-source method for aligning on-board and other pinhole SPECT systems.

PubMed

Yan, Susu; Bowsher, James; Yin, Fang-Fang

2013-12-01

In order to achieve functional and molecular imaging as patients are in position for radiation therapy, a robotic multipinhole SPECT system is being developed. Alignment of the SPECT system-to the linear accelerator (LINAC) coordinate frame and to the coordinate frames of other on-board imaging systems such as cone-beam CT (CBCT)-is essential for target localization and image reconstruction. An alignment method that utilizes line sources and one pinhole projection is proposed and investigated to achieve this goal. Potentially, this method could also be applied to the calibration of the other pinhole SPECT systems. An alignment model consisting of multiple alignment parameters was developed which maps line sources in three-dimensional (3D) space to their two-dimensional (2D) projections on the SPECT detector. In a computer-simulation study, 3D coordinates of line-sources were defined in a reference room coordinate frame, such as the LINAC coordinate frame. Corresponding 2D line-source projections were generated by computer simulation that included SPECT blurring and noise effects. The Radon transform was utilized to detect angles (α) and offsets (ρ) of the line-source projections. Alignment parameters were then estimated by a nonlinear least squares method, based on the α and ρ values and the alignment model. Alignment performance was evaluated as a function of number of line sources, Radon transform accuracy, finite line-source width, intrinsic camera resolution, Poisson noise, and acquisition geometry. Experimental evaluations were performed using a physical line-source phantom and a pinhole-collimated gamma camera attached to a robot. In computer-simulation studies, when there was no error in determining angles (α) and offsets (ρ) of the measured projections, six alignment parameters (three translational and three rotational) were estimated perfectly using three line sources. When angles (α) and offsets (ρ) were provided by the Radon transform, estimation accuracy was reduced. The estimation error was associated with rounding errors of Radon transform, finite line-source width, Poisson noise, number of line sources, intrinsic camera resolution, and detector acquisition geometry. Statistically, the estimation accuracy was significantly improved by using four line sources rather than three and by thinner line-source projections (obtained by better intrinsic detector resolution). With five line sources, median errors were 0.2 mm for the detector translations, 0.7 mm for the detector radius of rotation, and less than 0.5° for detector rotation, tilt, and twist. In experimental evaluations, average errors relative to a different, independent registration technique were about 1.8 mm for detector translations, 1.1 mm for the detector radius of rotation (ROR), 0.5° and 0.4° for detector rotation and tilt, respectively, and 1.2° for detector twist. Alignment parameters can be estimated using one pinhole projection of line sources. Alignment errors are largely associated with limited accuracy of the Radon transform in determining angles (α) and offsets (ρ) of the line-source projections. This alignment method may be important for multipinhole SPECT, where relative pinhole alignment may vary during rotation. For pinhole and multipinhole SPECT imaging on-board radiation therapy machines, the method could provide alignment of SPECT coordinates with those of CBCT and the LINAC.

Identification and Classification of Infrared Excess Sources in the Spitzer Enhanced Imaging Products (SEIP) Catalog

NASA Astrophysics Data System (ADS)

Strasburger, David; Gorjian, Varoujan; Burke, Todd; Childs, Linda; Odden, Caroline; Tambara, Kevin; Abate, Antoinette; Akhtar, Nadir; Beach, Skyler; Bhojwani, Ishaan; Brown, Caden; Dear, AnnaMaria; Dumont, Theodore; Harden, Olivia; Joli-Coeur, Laurent; Nahirny, Rachel; Nakahira, Andie; Nix, Sabine; Orgul, Sarp; Parry, Johnny; Picken, John; Taylor, Isabel; Toner, Emre; Turner, Aspen; Xu, Jessica; Zhu, Emily

2015-01-01

The Spitzer Space Telescope's original cryogenic mission imaged roughly 42 million sources, most of which were incidental and never specifically targeted for research. These have now been compiled in the publicly accessible Spitzer Enhanced Imaging Products (SEIP) catalog. The SEIP stores millions of never before examined sources that happened to be in the same field of view as objects specifically selected for study. This project examined the catalog to isolate previously unknown infrared excess (IRXS) candidates. The culling process utilized four steps. First, we considered only those objects with signal to noise ratios of at least 10 to 1 in the following five wavelengths: 3.6, 4.5, 5.8, 8 and 24 microns, which narrowed the source list to about one million. Second, objects were removed from highly studied regions, such as the galactic plane and previously conducted infrared surveys. This further reduced the population of sources to 283,758. Third, the remaining sources were plotted using a [3.6]-[4.5] vs. [8]-[24] color-color diagram to isolate IRXS candidates. Fourth, multiple images of sixty-three outlier points from the extrema of the color-color diagram were examined to verify that the sources had been cross matched correctly and to exclude any candidate sources that may have been compromised due to image artifacts or field crowding. The team will ultimately provide statistics for the prevalence of IRXS sources in the SEIP catalog and provide analysis of those extreme outliers from the main locus of points. This research was made possible through the NASA/IPAC Teacher Archive Research Program (NITARP) and was funded by NASA Astrophysics Data Program.

Thermal Analysis of Post-eruption Loops from 80,000 to 1.6 million K

NASA Technical Reports Server (NTRS)

Kucera, T.; Landi, E.

2006-01-01

We analyze the thermal properties of a set of post eruptive loops which appeared after a prominence eruption on April 30, 2004. The event was observed by TRACE and SOHO/SUMER. The SUMER data was taken from a single slit location with a 90 second cadence and included a number of lines spanning the temperature range 80,000 to 1.6 million K. We perform a differential emission measure analysis of the loops in order to study their thermal evolution.

40 CFR 467.25 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) EFFLUENT GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions Subcategory... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions...

Source, use, and disposition of water in Florida, 1980

USGS Publications Warehouse

Leach, S.D.

1983-01-01

An average of 21,206 million gallons of water was withdrawn for use in Florida each day for the combined use for public supplies , rural domestic and livestock, industrial self-supplied, irrigation, and thermoelectric power generation. This amount, broken down into 7,309 millions gallons per day of freshwater and 13,897 million gallons per day of saline water, indicates an increase of more than 40 percent for all uses during the 10-year period 1970-80. The largest user of freshwater in Florida was for irrigation--2,997 million gallons per day which also is responsible for the greatest consumption, 1,530 million gallons on the average each day or about half the water applied. The remaining use of freshwater amounted to 1,859 million gallons per day for thermoelectric power generation (which also used about 13.7 billion gallons per day of saline water); 1,361 million gallons per day of public supply; 797 million gallons per day for industrial use other than thermoelectric power generation; and 310 million gallons per day, on the average, for rural domestic and livestock use. (USGS)

Explanatory Supplement to the WISE All-Sky Release Products

NASA Technical Reports Server (NTRS)

2012-01-01

The Wide-field Infrared Survey Explorer (WISE; Wright et al. 2010) surveyed the entire sky at 3.4, 4.6, 12 and 22 microns in 2010, achieving 5-sigma point source sensitivities per band better than 0.08, 0.11, 1 and 6 mJy in unconfused regions on the ecliptic. The WISE All-Sky Data Release, conducted on March 14, 2012, incorporates all data taken during the full cryogenic mission phase, 7 January 2010 to 6 August 20l0,that were processed with improved calibrations and reduction algorithms. Release data products include: (1) an Atlas of 18,240 match-filtered, calibrated and coadded image sets; (2) a Source Catalog containing positions and four-band photometry for over 563 million objects, and (3) an Explanatory Supplement. Ancillary products include a Reject Table that contains 284 million detections that were not selected for the Source Catalog because they are low signal-to-noise ratio or spurious detections of image artifacts, an archive of over 1.5 million sets of calibrated WISE Single-exposure images, and a database of 9.4 billion source extractions from those single images, and moving object tracklets identified by the NEOWISE program (Mainzer et aI. 2011). The WISE All-Sky Data Release products supersede those from the WISE Preliminary Data Release (Cutri et al. 2011). The Explanatory Supplement to the WISE All-Sky Data Release Products is a general guide for users of the WISE data. The Supplement contains an overview of the WISE mission, facilities, and operations, a detailed description of WISE data processing algorithms, a guide to the content and formals of the image and tabular data products, and cautionary notes that describe known limitations of the All-Sky Release products. Instructions for accessing the WISE data products via the services of the NASA/IPAC Infrared Science Archive are provided. The Supplement also provides analyses of the achieved sky coverage, photometric and astrometric characteristics and completeness and reliability of the All-Sky Release data products. The WISE All-Sky Release Explanatory Supplement is an on-line document that is updated frequently to provide the most current information for users of the WISE data products. The Explanatory Supplement is maintained at: http://wise2.ipac.caltech.edu/docs/release/allsky/expsup/index.html WISE is a joint project of the University of California, Los Angeles and the Jet Propulsion Laboratory/California Institute of Technology, funded by the National Aeronautics and Space Administration. NEOWISE is a project of the Jet Propulsion Laboratory/California Institute of Technology, funded by the Planetary Science Division of the National Aeronautics and Space Administration.

A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations.

PubMed

Pinheiro, Eloan Dos Santos; Antunes, Octavio Augusto Ceva; Fortunak, Joseph M D

2008-09-01

It has been roughly 25 years since the threat posed by human immunodeficiency virus type 1 (HIV-1) became widely known. The cumulative death toll from HIV/AIDS is now greater than 25 million. There are approximately 33 million people living worldwide with this disease, of whom about 68% (22.5 million) live in sub-Saharan Africa (http://www.avert.org/worldstats.htm). A number of antiretroviral (ARV) drugs have been approved for treatment of HIV/AIDS. Inhibitors of HIV reverse transcriptase (RTIs) include the nucleoside/nucleotide drugs zidovudine, lamivudine, abacavir, didanosine, stavudine, emtricitabine and tenofovir disoproxil fumarate. Non-nucleoside RTIs include nevirapine, efavirenz and etravirine. Inhibitors of HIV protease (PIs) include saquinavir, ritonavir, lopinavir, nelfinavir, indinavir, fosamprenavir and atazanavir. Enfuvirtide inhibits the HIV fusion protein. The CCR5 chemokine antagonist maraviroc and the integrase inhibitor raltegravir were very recently approved by the US FDA. Fixed-dose combinations (FDCs) have been formulated to increase tolerability, convenience and compliance. First-line drug combinations are offered to treatment-naive patients, while second-line drugs are reserved for those who no longer respond adequately to first-line therapy. In developing countries a modest but increasing fraction of those infected have access to ARVs. The Clinton HIV/AIDS Initiative estimates that 2.4 million of the nearly 8 million individuals needing treatment in developing nations have access to some drugs. First-line FDCs used in resource-poor settings are largely combinations of two nucleoside RTIs and a non-nucleoside RTI or PI. The effectiveness of these combinations decreases over time, requiring a switch to combinations that retain potency in the presence of viral resistance. Increasing access to second-line FDCs and new developments in first-line ARV therapy are cost challenges. In high-income countries the cost of ARV therapy is largely irrelevant, except for "advanced salvage" drugs such as enfuvirtide. In resource-poor settings cost is a huge factor that limits drug access, resulting in high rates of new infection and subsequent mortality. IP coverage, where granted, can keep access prices for essential ARVs higher than would otherwise be the case. Large, innovator companies have made drugs available at prices very close to the cost of manufacturing for "lowest income" countries. Generic providers in India and elsewhere provide the largest supply of drugs for the developing world. The recent issuance of Voluntary and Compulsory Licenses (VLs, CLs) through the World Trade Organization's TRIP (Treaty Respecting Intellectual Property) provisions arguably contribute to bringing down access prices. The utilization of improved science, pooled purchasing and intelligent procurement practices all definitely contribute to access. This work surveys the production processes for several critical ARVs. These are discussed in terms of scale up, raw material/intermediates and active pharmaceutical ingredient (API) costs. In some cases new routes to APIs or critical intermediates are needed. Based on potential new chemistries, there are significant opportunities to reduce cost for a number of critical ARVs.

40 CFR 467.26 - Pretreatment standards for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions... for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions Chromium 0.048 0...

40 CFR 467.64 - New source performance standards.

Code of Federal Regulations, 2014 CFR

2014-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.64 - New source performance standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps Subcategory... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.66 - Pretreatment standards for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.26 - Pretreatment standards for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions... for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions Chromium 0.048 0...

40 CFR 467.66 - Pretreatment standards for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps Subcategory... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.26 - Pretreatment standards for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions... for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions Chromium 0.048 0...

40 CFR 467.66 - Pretreatment standards for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.64 - New source performance standards.

Code of Federal Regulations, 2012 CFR

2012-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.66 - Pretreatment standards for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

40 CFR 467.64 - New source performance standards.

Code of Federal Regulations, 2013 CFR

2013-07-01

... GUIDELINES AND STANDARDS (CONTINUED) ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Emulsions or Soaps... for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with emulsions or soaps Chromium...

Pharmacoeconomic analysis of consolidation therapy with pemetrexed after first-line chemotherapy for non-small cell lung cancer.

PubMed

Tsuchiya, Takanori; Fukuda, Takashi; Furuiye, Masashi; Kawabuchi, Koichi

2011-12-01

Prolongation of progression-free survival and overall survival have been reported with consolidation therapy after first-line chemotherapy in non-small cell lung cancer, but only a few pharmacoeconomic analyses have been performed. We performed a pharmacoeconomic analysis to assess the cost-effectiveness of consolidation therapy with pemetrexed compared with non-consolidation therapy. We developed a Markov model to evaluate the incremental cost-effectiveness ratio (ICER) of consolidation therapy with pemetrexed compared with non-consolidation therapy based on previous reports. We analyzed all histology groups together, and individually analyzed non-squamous cell carcinoma, in which pemetrexed has been shown to be more effective, and squamous cell carcinoma, in which pemetrexed has been shown to be less effective. We conducted a Monte-Carlo simulation to assess the uncertainty for our analysis model and the willingness to pay using thresholds. The ICER for consolidation therapy with pemetrexed was about US$ 109,024/life years gained (LYG) (JPY 12.5 million/LYG) and US$ 203,022/quality-adjusted life years (QALY) (JPY 23.3 million/QALY) for all histology. For non-squamous cell carcinoma, respective values were US$ 80,563/LYG (JPY 9.3 million/LYG) and US$ 150,115/QALY (JPY 17.3 million/QALY). Both % of probability at a threshold of JPY 5.0 million (US$ 43,478) for all histology and non-squamous cell carcinoma were less than 0.1%. This result indicates that it is difficult to use consolidation therapy as the standard of care in Japan while being covered by general medical insurance. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Italian Contributions to the Development of Continuous Glucose Monitoring Sensors for Diabetes Management

PubMed Central

Sparacino, Giovanni; Zanon, Mattia; Facchinetti, Andrea; Zecchin, Chiara; Maran, Alberto; Cobelli, Claudio

2012-01-01

Monitoring glucose concentration in the blood is essential in the therapy of diabetes, a pathology which affects about 350 million people around the World (three million in Italy), causes more than four million deaths per year and consumes a significant portion of the budget of national health systems (10% in Italy). In the last 15 years, several sensors with different degree of invasiveness have been proposed to monitor glycemia in a quasi-continuous way (up to 1 sample/min rate) for relatively long intervals (up to 7 consecutive days). These continuous glucose monitoring (CGM) sensors have opened new scenarios to assess, off-line, the effectiveness of individual patient therapeutic plans from the retrospective analysis of glucose time-series, but have also stimulated the development of innovative on-line applications, such as hypo/hyper-glycemia alert systems and artificial pancreas closed-loop control algorithms. In this review, we illustrate some significant Italian contributions, both from industry and academia, to the growth of the CGM sensors research area. In particular, technological, algorithmic and clinical developments performed in Italy will be discussed and put in relation with the advances obtained in the field in the wider international research community. PMID:23202020

Italian contributions to the development of continuous glucose monitoring sensors for diabetes management.

PubMed

Sparacino, Giovanni; Zanon, Mattia; Facchinetti, Andrea; Zecchin, Chiara; Maran, Alberto; Cobelli, Claudio

2012-10-12

Monitoring glucose concentration in the blood is essential in the therapy of diabetes, a pathology which affects about 350 million people around the World (three million in Italy), causes more than four million deaths per year and consumes a significant portion of the budget of national health systems (10% in Italy). In the last 15 years, several sensors with different degree of invasiveness have been proposed to monitor glycemia in a quasi-continuous way (up to 1 sample/min rate) for relatively long intervals (up to 7 consecutive days). These continuous glucose monitoring (CGM) sensors have opened new scenarios to assess, off-line, the effectiveness of individual patient therapeutic plans from the retrospective analysis of glucose time-series, but have also stimulated the development of innovative on-line applications, such as hypo/hyper-glycemia alert systems and artificial pancreas closed-loop control algorithms. In this review, we illustrate some significant Italian contributions, both from industry and academia, to the growth of the CGM sensors research area. In particular, technological, algorithmic and clinical developments performed in Italy will be discussed and put in relation with the advances obtained in the field in the wider international research community.

Irrigated acreage and other land uses on the Snake River Plain, Idaho and eastern Oregon

USGS Publications Warehouse

Lindholm, Gerald F.; Goodell, S.A.

1986-01-01

Prompted by the need for a current, accurate, and repeatable delineation of irrigated acreage on the Snake River Plain, the U.S. Geological Survey entered into a cooperative agreement with the Idaho Department of Water Resources Image Analysis Facility and the U.S. Bureau of Reclamation to delineate 1980 land use form Landsat data. Irrigated acreage data were needed as input to groundwater flow models developed by the U.S. Geological Survey in a study of the regional aquifer system underlying the Snake River Plain. Single-date digital multispectral scanner data analyzed to delineate land-use classes. Source of irrigation water (surface water, ground water, and combined) was determined from county maps of 1975 water-related land use, data from previous investigations, and field checking. Surface-water diversions for irrigation on the Snake River Plain began in the 1840's. With the stimulus of Federal aid authorized by the Desert Land Act, Carey Act, and Reclamation Act, irrigated area increased rapidly in the early 1900's. By 1929, 2.2 million acres were irrigated. Ground water became and important source of irrigation water after World War II. In 1980, about 3.1 million acres of the Snake River Plain were irrigate: 2.0 million acres with surface water, 1.0 million with ground water, and 0.1 million with combined surface and ground water. About 5.2 million acres (half of the plain) are undeveloped rangeland, 1.0 million acres (one-tenth) are classified as barren. The remaining land is a mixture of dryland agriculture, water bodies, wetland, forests, and urban areas.

ARC-1989-A89-7005

NASA Image and Video Library

1989-08-17

August 17 to 19, 1989 Range : 11.5 million km (7.1 million mi.) to 7.9 million km (4.9 million mi.) Four black and white images of Neptune's largest satellite, Triton, show it's rotation between the first (upper left) image and the last (lower right). Resolution improves from about 200 km (124 miles) to 150 km (93 miles) per line pair. Triton's south pole lies in the dark area near the bottom of the disk. Dark spots, roughly 1,000 km (620 miles) across, occur near the equator, and show Triton rotation between images. The rotation appears to be synchronous with Triton's 5.88-day orbital period (i.e., Triton rotates on its axis in the same time it revolves around Neptune.) The spots' constant rotation rate and their visibility near the edge of the disk suggest the spots are surface features. Whatever atmosphere is present on Triton appears transparent enough that Voyager 2's cameras can see through it.

Alabama rail directory 2001

DOT National Transportation Integrated Search

2002-01-01

The State of Alabama is crisscrossed by some 4,728 miles rail lines hauling 93.5 million tons of cargo annually. This directory, Alabama's first comprehensive rail directory, provides a range of information regarding railroads operating in the state,...

Photographer : JPL Range : 4.2 million kilometers (2.6 million miles) Ganymede is Jupiter's Largest

NASA Technical Reports Server (NTRS)

1979-01-01

Photographer : JPL Range : 4.2 million kilometers (2.6 million miles) Ganymede is Jupiter's Largest Galilean satellites and 3rd from the planet. Photo taken after midnight Ganymede is slightly larger than Mercury but much less dense (twice the density of water). Its surface brightness is 4 times of Earth's Moon. Mare regions (dark features) are like the Moon's but have twice the brightness, and believed to be unlikely of rock or lava as the Moon's are. It's north pole seems covered with brighter material and may be water frost. Scattered brighter spots may be related to impact craters or source of fresh ice.

Photographer : JPL Range : 6 million kilometers (3.7 million miles) Central Longitude 120 degrees

NASA Technical Reports Server (NTRS)

1979-01-01

Photographer : JPL Range : 6 million kilometers (3.7 million miles) Central Longitude 120 degrees west, North is up. and 3rd from the planet. Photo taken after midnight Ganymede is slightly larger than Mercury but much less dense (twice the density of water). Its surface brightness is 4 times of Earth's Moon. Mare regions (dark features) are like the Moon's but have twice the brightness, and believed to be unlikely of rock or lava as the Moon's are. It's north pole seems covered with brighter material and may be water frost. Scattered brighter spots may be related to impact craters or source of fresh ice.

CHROMOSPHERIC NANOFLARES AS A SOURCE OF CORONAL PLASMA. II. REPEATING NANOFLARES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradshaw, S. J.; Klimchuk, J. A., E-mail: stephen.bradshaw@rice.edu, E-mail: James.A.Klimchuk@nasa.gov

The million degree plasma of the solar corona must be supplied by the underlying layers of the atmosphere. The mechanism and location of energy release, and the precise source of coronal plasma, remain unresolved. In earlier work, we pursued the idea that warm plasma is supplied to the corona via direct heating of the chromosphere by nanoflares, contrary to the prevailing belief that the corona is heated in situ and the chromosphere is subsequently energized and ablated by thermal conduction. We found that single (low-frequency) chromospheric nanoflares could not explain the observed intensities, Doppler-shifts, and red/blue asymmetries in Fe xiimore » and xiv emission lines. In the present work, we follow up on another suggestion that the corona could be powered by chromospheric nanoflares that repeat on a timescale substantially shorter than the cooling/draining timescale. That is, a single magnetic strand is re-supplied with coronal plasma before the existing plasma has time to cool and drain. We perform a series of hydrodynamic experiments and predict the Fe xii and xiv line intensities, Doppler-shifts, and red/blue asymmetries. We find that our predicted quantities disagree dramatically with observations and fully developed loop structures cannot be created by intermediate- or high-frequency chromospheric nanoflares. We conclude that the mechanism ultimately responsible for producing coronal plasma operates above the chromosphere, but this does not preclude the possibility of a similar mechanism powering the chromosphere, extreme examples of which may be responsible for heating chromospheric plasma to transition region temperatures (e.g., type II spicules)« less

New gas-pipeline system planned for Argentina

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andrich, V.

1979-03-01

A new gas-pipeline system planned for Argentina by Gas del Estado will carry up to 10 million cu m/day to Mendoza, San Juan, and San Luis from the Neuquen basin. Operating on a toll system of transport payment, the Centro-Oeste pipeline system will consist of 1100 km of over 30 in. dia trunk line and 600 km of 8, 12, and 18 in. dia lateral lines.

History of Chandra X-Ray Observatory

NASA Image and Video Library

1999-12-01

This Chandra image shows the central regions of two colliding galaxies known collectively as the Antennae (NGC-4038/4039). The dozens of bright pointy-like sources are neutron stars or black holes pulling gas off nearby stars. The bright fuzzy patches are multimillion degree gas superbubbles, thousands of light years in diameter that were produced by the accumulated power of thousands of supernovae. The remaining glow of x-ray emission could be due to many faint x-ray sources or to clouds of hot gas in the galaxies. About 60 million light years from Earth in the constellation Corvus, the Antennae Galaxies got their nickname from the wispy anntennae-like streams of gas as seen by optical telescopes. These ongoing wisps are believed to have been produced approximately 100 million years ago by the collision between the galaxies. Although it is rare for stars to hit each other during a galactic collision, clouds of dust and gas do collide. Compression of these clouds can lead to the rebirth of millions of stars, and a few million years later, to thousands of supernovae.

Market assessment of tuberculosis diagnostics in India in 2013.

PubMed

Maheshwari, P; Chauhan, K; Kadam, R; Pujani, A; Kaur, M; Chitalia, M; Dabas, H; Perkins, M D; Boehme, C C; Denkinger, C M; Raizada, N; Ginnard, J; Jefferson, C; Pantoja, A; Rupert, S; Kik, S V; Cohen, C; Chedore, P; Satyanarayana, S; Pai, M

2016-03-01

India represents a significant potential market for new tests. We assessed India's market for tuberculosis (TB) diagnostics in 2013. Test volumes and unit costs were assessed for tuberculin tests, interferon-gamma release assays, sputum smear microscopy, serology, culture, speciation testing, nucleic-acid amplification tests (i.e., in-house polymerase chain reaction, Xpert(®) MTB/RIF, line-probe assays) and drug susceptibility testing. Data from the public sector were collected from the Revised National TB Control Programme reports. Private sector data were collected through a survey of private laboratories and practitioners. Data were also collected from manufacturers. In 2013, India's public sector performed 19.2 million tests, with a market value of US$22.9 million. The private sector performed 13.6 million tests, with a market value of US$60.4 million when prices charged to the patient were applied. The overall market was US$70.8 million when unit costs from the ingredient approach were used for the 32.8 million TB tests performed in the entire country. Smear microscopy was the most common test performed, accounting for 25% of the overall market value. India's estimated market value for TB diagnostics in 2013 was US$70.8 million. These data should be of relevance to test developers, donors and implementers.

A correlation between hard gamma-ray sources and cosmic voids along the line of sight

DOE PAGES

Furniss, A.; Sutter, P. M.; Primack, J. R.; ...

2014-11-25

We estimate the galaxy density along lines of sight to hard extragalactic gamma-ray sources by correlating source positions on the sky with a void catalog based on the Sloan Digital Sky Survey (SDSS). Extragalactic gamma-ray sources that are detected at very high energy (VHE; E > 100 GeV) or have been highlighted as VHE-emitting candidates in the Fermi Large Area Telescope hard source catalog (together referred to as “VHE-like” sources) are distributed along underdense lines of sight at the 2.4σ level. There is a less suggestive correlation for the Fermi hard source population (1.7σ). A correlation between 10-500 GeV fluxmore » and underdense fraction along the line of sight for VHE-like and Fermi hard sources is found at 2.4σ and 2.6σ, calculated from the Pearson correlation coefficients of r = 0.57 and 0.47, respectively. The preference for underdense sight lines is not displayed by gamma-ray emitting galaxies within the second Fermi catalog, containing sources detected above 100 MeV, or the SDSS DR7 quasar catalog. We investigate whether this marginal correlation might be a result of lower extragalactic background light (EBL) photon density within the underdense regions and find that, even in the most extreme case of a entirely underdense sight line, the EBL photon density is only 2% less than the nominal EBL density. Translating this into gamma-ray attenuation along the line of sight for a highly attenuated source with opacity τ(E, z) ~ 5, we estimate that the attentuation of gamma-rays decreases no more than 10%. This decrease, although non-neglible, is unable to account for the apparent hard source correlation with underdense lines of sight.« less

Optimization of a Focusable and Rotatable Shear-Wave Periodic Permanent Magnet Electromagnetic Acoustic Transducers for Plates Inspection

PubMed Central

Qiu, Gongzhe

2017-01-01

Due to the symmetry of conventional periodic-permanent-magnet electromagnetic acoustic transducers (PPM EMATs), two shear (SH) waves can be generated and propagated simultaneously in opposite directions, which makes the signal recognition and interpretation complicatedly. Thus, this work presents a new SH wave PPM EMAT design, rotating the parallel line sources to realize the wave beam focusing in a single-direction. The theoretical model of distributed line sources was deduced firstly, and the effects of some parameters, such as the inner coil width, adjacent line sources spacing and the angle between parallel line sources, on SH wave focusing and directivity were studied mainly with the help of 3D FEM. Employing the proposed PPM EMATs, some experiments are carried out to verify the reliability of FEM simulation. The results indicate that rotating the parallel line sources can strength the wave on the closing side of line sources, decreasing the inner coil width and the adjacent line sources spacing can improve the amplitude and directivity of signals excited by transducers. Compared with traditional PPM EMATs, both the capacity of unidirectional excitation and directivity of the proposed PPM EMATs are improved significantly. PMID:29186790

Optimization of a Focusable and Rotatable Shear-Wave Periodic Permanent Magnet Electromagnetic Acoustic Transducers for Plates Inspection.

PubMed

Song, Xiaochun; Qiu, Gongzhe

2017-11-24

Due to the symmetry of conventional periodic-permanent-magnet electromagnetic acoustic transducers (PPM EMATs), two shear (SH) waves can be generated and propagated simultaneously in opposite directions, which makes the signal recognition and interpretation complicatedly. Thus, this work presents a new SH wave PPM EMAT design, rotating the parallel line sources to realize the wave beam focusing in a single-direction. The theoretical model of distributed line sources was deduced firstly, and the effects of some parameters, such as the inner coil width, adjacent line sources spacing and the angle between parallel line sources, on SH wave focusing and directivity were studied mainly with the help of 3D FEM. Employing the proposed PPM EMATs, some experiments are carried out to verify the reliability of FEM simulation. The results indicate that rotating the parallel line sources can strength the wave on the closing side of line sources, decreasing the inner coil width and the adjacent line sources spacing can improve the amplitude and directivity of signals excited by transducers. Compared with traditional PPM EMATs, both the capacity of unidirectional excitation and directivity of the proposed PPM EMATs are improved significantly.

40 CFR 467.24 - New source performance standards.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions Subcategory § 467.24... for monthly average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions Chromium 0.048 0...

SESAME -- A third generation synchrotron light source for the Middle East

NASA Astrophysics Data System (ADS)

Winick, Herman

2012-03-01

Developed under the auspices of UNESCO and modeled on CERN, SESAME (Synchrotron-light for Experimental Science and Applications in the Middle East) is an international research centre in construction in Jordan, enabling world-class research while promoting peace through scientific cooperation. Its centerpiece, a new 2.5 GeV 3rd Generation Electron Storage Ring (133m circumference, 26nm-rad emittance, 12 places for insertion devices), will provide intense light from infra-red to hard X-rays. Members of the Council (Bahrain, Cyprus, Egypt, Iran, Israel, Jordan, Pakistan, Palestinian Authority,Turkey) provide the operations budget. Voluntary contributions by several Council Members that could amount to over 20 million over 5 years are now being finalized. This, plus funds from other sources, will enable acquisition of the technical components of the new ring and the upgrading of beamline equipment donated by several European and US labs. All concrete shielding is complete. The 0.8 GeV BESSY I injector system, a gift from Germany, is now being installed. A training program has been underway since 2000. SESAME is on track to start operation with four day-one beam lines in 2015.

The Emergence of Open-Source Software in North America

ERIC Educational Resources Information Center

Pan, Guohua; Bonk, Curtis J.

2007-01-01

Unlike conventional models of software development, the open source model is based on the collaborative efforts of users who are also co-developers of the software. Interest in open source software has grown exponentially in recent years. A "Google" search for the phrase open source in early 2005 returned 28.8 million webpage hits, while…

Multi-kanban mechanism for personal computer disassembly

NASA Astrophysics Data System (ADS)

Udomsawat, Gun; Gupta, Surendra M.; Kamarthi, Sagar V.

2004-12-01

The use of personal computers (PCs) continues to increase every year. According to a 1999 figure, 50 percent of all US households owned PCs, a figure that continues to rise every year. With continuous development of sophisticated software, PCs are becoming increasingly powerful. In addition, the price of a PC continues to steadily decline. Furthermore, the typical life of a PC in the workplace is approximately two to three years while in the home it is three to five years. As these PCs become obsolete, they are replaced and the old PCs are disposed of. It is estimated that between 14 and 20 million PCs are retired annually in the US. While 20 to 30% of the units may be resold, the others are discarded. These discards represent a significant potential source of lead for the waste stream. In some communities, waste cathode ray tubes (CRTs) represent the second largest source of lead in the waste stream after vehicular lead acid batteries. PCs are, therefore, not suitable for dumping in landfills. Besides, several components of a PC can be reused and then there are other valuable materials that can also be harvested. And with the advent of product stewardship, product recovery is the best solution for manufacturers. Disassembly line is perhaps the most suitable set up for disassembling PCs. However, planning and scheduling of disassembly on a disassembly line is complicated. In this paper, we discuss some of the complications including product arrival, demand arrival, inventory fluctuation and production control mechanisms. We then show how to overcome them by implementing a multi-kanban mechanism in the PC disassembly line setting. The multi-kanban mechanism relies on dynamic routing of kanbans according to the state of the system. We investigate the multi-kanban mechanism using simulation and demonstrate that this mechanism is superior to the traditional push system in terms of controlling the system"s inventory while maintaining a decent customer service level.

Prevalence and effects of multiple chemical sensitivities in Australia.

PubMed

Steinemann, Anne

2018-06-01

Multiple chemical sensitivities (MCS) is a medical condition associated with exposure to common chemical pollutants. The aims of this study are to assess the prevalence of MCS, its overlaps with asthma and fragrance sensitivity, and its health and societal effects in Australia. Data were collected in June 2016 using an on-line survey with a representative national sample (N = 1098) of adults (ages 18-65) in Australia. Results found that, across the country, 6.5% report medically diagnosed MCS, 18.9% report chemical sensitivity (being unusually sensitive to everyday chemicals and chemically formulated products), and 19.9% either or both. Among people with MCS, 74.6% also have diagnosed asthma or an asthma-like condition, and 91.5% have fragrance sensitivity, reporting health problems (such as migraine headaches) when exposed to fragranced consumer products (such as air fresheners and cleaning supplies). In addition, among people with MCS, 77.5% are prevented from access to places because of fragranced products, 52.1% lost workdays or a job in the past year due to fragranced product exposure in the workplace, and 55.4% report health effects considered potentially disabling. Results indicate that MCS is a widespread disease, affecting an estimated 1 million adult Australians, with chemical sensitivity affecting another 2 million. Reducing chemical exposure to problematic sources, such as fragranced consumer products, is critical to reduce adverse effects.

Quantitative assessment of the expanding complementarity between public and commercial databases of bioactive compounds.

PubMed

Southan, Christopher; Várkonyi, Péter; Muresan, Sorel

2009-07-06

Since 2004 public cheminformatic databases and their collective functionality for exploring relationships between compounds, protein sequences, literature and assay data have advanced dramatically. In parallel, commercial sources that extract and curate such relationships from journals and patents have also been expanding. This work updates a previous comparative study of databases chosen because of their bioactive content, availability of downloads and facility to select informative subsets. Where they could be calculated, extracted compounds-per-journal article were in the range of 12 to 19 but compound-per-protein counts increased with document numbers. Chemical structure filtration to facilitate standardised comparisons typically reduced source counts by between 5% and 30%. The pair-wise overlaps between 23 databases and subsets were determined, as well as changes between 2006 and 2008. While all compound sets have increased, PubChem has doubled to 14.2 million. The 2008 comparison matrix shows not only overlap but also unique content across all sources. Many of the detailed differences could be attributed to individual strategies for data selection and extraction. While there was a big increase in patent-derived structures entering PubChem since 2006, GVKBIO contains over 0.8 million unique structures from this source. Venn diagrams showed extensive overlap between compounds extracted by independent expert curation from journals by GVKBIO, WOMBAT (both commercial) and BindingDB (public) but each included unique content. In contrast, the approved drug collections from GVKBIO, MDDR (commercial) and DrugBank (public) showed surprisingly low overlap. Aggregating all commercial sources established that while 1 million compounds overlapped with PubChem 1.2 million did not. On the basis of chemical structure content per se public sources have covered an increasing proportion of commercial databases over the last two years. However, commercial products included in this study provide links between compounds and information from patents and journals at a larger scale than current public efforts. They also continue to capture a significant proportion of unique content. Our results thus demonstrate not only an encouraging overall expansion of data-supported bioactive chemical space but also that both commercial and public sources are complementary for its exploration.

40 CFR 471.13 - New source performance standards (NSPS).

Code of Federal Regulations, 2013 CFR

2013-07-01

...-Tin-Bismuth Forming Subcategory § 471.13 New source performance standards (NSPS). Any new source... pollutants in the lead-tin-bismuth forming operations' process wastewater shall not exceed the following... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.13 - New source performance standards (NSPS).

Code of Federal Regulations, 2014 CFR

2014-07-01

...-Tin-Bismuth Forming Subcategory § 471.13 New source performance standards (NSPS). Any new source... pollutants in the lead-tin-bismuth forming operations' process wastewater shall not exceed the following... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.13 - New source performance standards (NSPS).

Code of Federal Regulations, 2012 CFR

2012-07-01

...-Tin-Bismuth Forming Subcategory § 471.13 New source performance standards (NSPS). Any new source... pollutants in the lead-tin-bismuth forming operations' process wastewater shall not exceed the following... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.73 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUIDELINES AND STANDARDS NONFERROUS METALS FORMING AND METAL POWDERS POINT SOURCE CATEGORY Uranium Forming... achieve the following new source performance standards (NSPS). The mass of pollutants in the uranium... mg/off-kg (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium 0.013 0...

40 CFR 471.73 - New source performance standards (NSPS).

Code of Federal Regulations, 2012 CFR

2012-07-01

... Uranium Forming Subcategory § 471.73 New source performance standards (NSPS). Any new source subject to... in the uranium forming process wastewater shall not exceed the following values: (a) Extrusion spent... monthly average mg/off-kg (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium...

40 CFR 471.73 - New source performance standards (NSPS).

Code of Federal Regulations, 2013 CFR

2013-07-01

... Uranium Forming Subcategory § 471.73 New source performance standards (NSPS). Any new source subject to... in the uranium forming process wastewater shall not exceed the following values: (a) Extrusion spent... monthly average mg/off-kg (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium...

40 CFR 471.73 - New source performance standards (NSPS).

Code of Federal Regulations, 2014 CFR

2014-07-01

... Uranium Forming Subcategory § 471.73 New source performance standards (NSPS). Any new source subject to... in the uranium forming process wastewater shall not exceed the following values: (a) Extrusion spent... monthly average mg/off-kg (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium...

40 CFR 471.73 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS NONFERROUS METALS FORMING AND METAL POWDERS POINT SOURCE CATEGORY Uranium Forming... achieve the following new source performance standards (NSPS). The mass of pollutants in the uranium... mg/off-kg (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium 0.013 0...

40 CFR 421.84 - Standards of performance for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Primary Zinc... achieve the following new source performance standards: (a) Subpart H—Zinc Reduction Furnace Wet Air.../kg (pounds per million pounds) of zinc reduced Cadmium .334 .134 Copper 2.135 1.018 Lead .467 .217...

EVALUATING THE EFFECTS OF UPSTREAM DISCHARGERS ON DOWNSTREAM WATER SUPPLIES: A SOURCE WATER PROTECTION MODEL

EPA Science Inventory

Source water protection is a component of the 1996 Amendments to the Safe Drinking Water Act. Drinking water utilities have adopted widely different philosophies for source water protection. the City of New York, with large upland water reservoirs, is investing millions of doll...

Iran: U.S. Concerns and Policy Responses

DTIC Science & Technology

2008-09-24

Iran’s total pistachio nut production. President Mahmoud Ahmadinejad Leads faction of younger, harder line conservatives associated with...juice, caviar, pistachio nuts, carpets, medicines, artwork). Imports from U.S. — $146 million (food, medicines, tobacco products, seeds). Foreign

A virtual observatory for photoionized nebulae: the Mexican Million Models database (3MdB).

NASA Astrophysics Data System (ADS)

Morisset, C.; Delgado-Inglada, G.; Flores-Fajardo, N.

2015-04-01

Photoionization models obtained with numerical codes are widely used to study the physics of the interstellar medium (planetary nebulae, HII regions, etc). Grids of models are performed to understand the effects of the different parameters used to describe the regions on the observables (mainly emission line intensities). Most of the time, only a small part of the computed results of such grids are published, and they are sometimes hard to obtain in a user-friendly format. We present here the Mexican Million Models dataBase (3MdB), an effort to resolve both of these issues in the form of a database of photoionization models, easily accessible through the MySQL protocol, and containing a lot of useful outputs from the models, such as the intensities of 178 emission lines, the ionic fractions of all the ions, etc. Some examples of the use of the 3MdB are also presented.

Road traffic injuries and data systems in Egypt: addressing the challenges.

PubMed

Puvanachandra, P; Hoe, C; El-Sayed, H F; Saad, R; Al-Gasseer, N; Bakr, M; Hyder, A A

2012-01-01

Road traffic injuries (RTIs) are a major cause of global mortality and morbidity, killing approximately 1.3 million people and injuring 20 to 50 million each year. The significance of this public health threat is most pronounced in low- and middle-income countries where 90 percent of the world's road traffic-related fatalities take place. Current estimates for Egypt show a road traffic fatality rate of 42 deaths per 100,000 population-one of the highest in the Eastern Mediterranean Region. RTIs are also responsible for 1.8 percent of all deaths and 2.4 percent of all disability-adjusted life years (DALYs) lost in the country. Despite this, studies surrounding this topic are scarce, and reliable data are limited. The overall goal of this article is to define the health impact of RTIs in Egypt and to identify the strengths and weaknesses of each data source for the purpose of improving the current RTI data systems. A 2-pronged approach was undertaken to assess the burden of RTIs in Egypt. First, a thorough literature review was performed using PubMed, Embase, ISIS Web of Knowledge, and Scopus databases. Articles pertaining to Egypt and road traffic injuries were selected for screening. With assistance from Egyptian colleagues, a comprehensive exploration of data sources pertaining to RTIs in Egypt was undertaken and secondary data from these sources were procured for analysis. The literature review yielded a total of 20 studies, of which 6 were multi-country and 5 were hospital-based studies. None examined risk factors such as speeding, alcohol, or seat belt use. Secondary data sources were acquired from national hospital-based injury surveillance; a community-based health survey; pre-hospital injury surveillance; the Ministry of Transport; the General Authority for Roads, Bridges and Land Transport; death certificates; and the central agency for public motorization and statistics. Risk factor data are also limited from these sources. The results of this article clearly highlight the significant burden that road traffic injuries pose on the health of the Egyptian population. The hospital-based injury surveillance system that has been established in the country and the use of International Classification of Diseases (ICD-10) coding brings the system very closely in line with international guidelines. There is, however, some considerable room for improvement, including the need to extend the coverage of the surveillance system, the inclusion of injury severity scores and disability indicators, and standardization of the sometimes rather disparate sources from various sectors in order to maximally capture the true burden of RTIs.

40 CFR 467.26 - Pretreatment standards for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Rolling With Emulsions Subcategory § 467.26... average mg/off-kg (lb/million off-lbs) of aluminum rolled with emulsions Chromium 0.048 0.020 Cyanide 0...

21 CFR 573.320 - Diammonium phosphate.

Code of Federal Regulations, 2011 CFR

2011-04-01

... (nitrogen × 6.25) and 20 percent phosphorus. It contains not more than the following: 1 part fluorine to 100 parts phosphorus. 75 parts per million or arsenic (as As). 30 parts per million of heavy metals, as lead (Pb). (b) It is used in ruminant feeds as a source of phosphorus and nitrogen in an amount that...

21 CFR 573.320 - Diammonium phosphate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... (nitrogen × 6.25) and 20 percent phosphorus. It contains not more than the following: 1 part fluorine to 100 parts phosphorus. 75 parts per million or arsenic (as As). 30 parts per million of heavy metals, as lead (Pb). (b) It is used in ruminant feeds as a source of phosphorus and nitrogen in an amount that...

40 CFR 471.103 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... mg/off-kg (pounds per million off-pounds) of powder metallurgy parts steam treated Copper 0.151 0.079... million off-pounds) of powder metallurgy parts tumbled, burnished, or cleaned Copper 0.836 0.440 Cyanide 0... off-pounds) of powder metallurgy parts sawed or ground with emulsions Copper 0.035 0.018 Cyanide 0.005...

40 CFR 471.105 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... mg/off-kg (pounds per million off-pounds) of powder metallurgy parts steam treated Copper 0.151 0.079... million off-pounds) of powder metallurgy parts tumbled, burnished, or cleaned Copper 0.836 0.440 Cyanide 0... off-pounds) of powder metallurgy parts sawed or ground with emulsions Copper 0.035 0.018 Cyanide 0.005...

Revival and Identification of Bacterial Spores in 25- to 40-Million-Year-Old Dominican Amber

NASA Astrophysics Data System (ADS)

Cano, Raul J.; Borucki, Monica K.

1995-05-01

A bacterial spore was revived, cultured, and identified from the abdominal contents of extinct bees preserved for 25 to 40 million years in buried Dominican amber. Rigorous surface decontamination of the amber and aseptic procedures were used during the recovery of the bacterium. Several lines of evidence indicated that the isolated bacterium was of ancient origin and not an extant contaminant. The characteristic enzymatic, biochemical, and 16S ribosomal DNA profiles indicated that the ancient bacterium is most closely related to extant Bacillus sphaericus.

A global tectonic activity map with orbital photographic supplement

NASA Technical Reports Server (NTRS)

Lowman, P. D., Jr.

1981-01-01

A three part map showing equatorial and polar regions was compiled showing tectonic and volcanic activity of the past one million years, including the present. Features shown include actively spreading ridges, spreading rates, major active faults, subduction zones, well defined plates, and volcanic areas active within the past one million years. Activity within this period was inferred from seismicity (instrumental and historic), physiography, and published literature. The tectonic activity map was used for planning global geodetic programs of satellite laser ranging and very long base line interferometry and for geologic education.

Experts warn against cutting NOAA Space Weather Center

NASA Astrophysics Data System (ADS)

Showstack, Randy

A well-timed congressional hearing, coming in the midst of fierce geomagnetic storms, could help to restore funding to the U.S. National Oceanic and Atmospheric Administration's Space Environment Center (SEC).The center, which is the nation's official source of space weather alerts and warnings, currently is funded at $5.24 million for fiscal year 2003. That amount is $2 million less than it received the previous year. The Bush Administration has requested $8.02 million in funding. The appropriations bill, for the departments of Commerce, Justice, and State for fiscal year 2004, passed on 23 July by the House of Representatives, calls for funding the SEC at the $5.29 million level.

Year 2001 Alabama rail plan update

DOT National Transportation Integrated Search

2002-01-01

The State of Alabama is crisscrossed by some 4,728 miles rail lines hauling 93.5 million tons of cargo annually. There are five Class I railroads that operate in Alabama: Burlington Northern Santa Fe, Canadian National/Illinois Central, CSX Transport...

A Quasar Turns On

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-02-01

The intermediate Palomar Transient Factory (iPTF) has discovered a quasar the brightly-shining, active nucleus of a galaxy abruptly turning on in what appears to be the fastest such transition ever seen in such an object.A Rapid TransitionQuasars are expected to show variations in brightness on timescales of hours to millions of years, but its not often that we get to study their major variability in real time! So far, weve discovered only a dozen changing-look quasars active galactic nuclei that exhibit major changes in their spectral class and brightness between observations. Roughly half of these were quasars that turned on and half were quasars that turned off, generally on timescales of maybe 5 or 10 years.The dramatic change in spectrum of iPTF 16bco between the archival SDSS data from 2004 (bottom) and the follow-up spectroscopy from Keck 2+DEIMOS in 2016 (top). [Adapted from Gezari et al. 2017]In June 2016, however, a team of scientists led by Suvi Gezari (University of Maryland) discovered iPTF 16bco, a nuclear transient that wasnt there the last time Palomar checked in 2012. A search through archival Sloan Digital Sky Survey and GALEX data in addition to some follow-up X-ray imaging and spectroscopic observations told the team what they needed to know: iPTF 16bco is a quasar that only just turned on within the 500 days preceding the iPTF observations.This source, in fact, is a 100-million-solar-mass black hole located at the center of a galaxy at a redshift of z= 0.237. In just over a year, the source changed classification from a galaxy with weak narrow-line emission to a quasar with characteristic strong, broad emission lines and a ten-fold increase in continuum brightness! What caused this sudden transition?Instabilities at Fault?iPTF 16bco and the other known changing-look quasars with disappearing (red circles) and appearing (blue circles) broad-line emission. [Adapted from Gezari et al. 2017]Gezari and collaborators used the large number of recent and archival observations of the galaxy to explore several scenarios that might be responsible for the rapid change in its brightness and spectral appearance. They found that the data disfavor variable obscuration by an absorber between us and the galaxy, microlensing of a background object, and tidal disruption of a star.Instead, the authors conclude that the best-fitting explanation is one in which thegalaxys nucleus already had a preexisting accretion disk, but the disk recently developed an instability. That instability caused more gas to rapidly feed onto the black hole, bumping the accretion rate up a notch and resulting in the quasar suddenlybrightening.Continued observations ofiPTF 16bcowill certainly help us to better understand whats happening in this unusual source. In the meantime, itsrapid change of state pushes the limits of accretion disk theory and presents us with an intriguing challenge to our understanding of quasars.CitationS. Gezari et al 2017 ApJ 835 144. doi:10.3847/1538-4357/835/2/144

The Ice Line in Pre-Solar Protoplanetary Disks

NASA Technical Reports Server (NTRS)

Davis, Sanford S.

2012-01-01

Protoplanetary disks contain abundant quantities of water molecules in both gas and solid phases. The distribution of these two phases in an evolving protoplanetary disk will have important consequences regarding water sequestration in planetary embryos. The boundary between gaseous and solid water is the "ice line" or "snow line" A simplified model that captures the complicated two-branched structure of the ice line is developed and compared with recent investigations. The effect of an evolving Sun is also included for the first time. This latter parameter could have important consequences regarding the thermodynamic state and the surface reaction environment for the time-dependent chemical reactions occurring during the 1- to 10-million-year lifetime of the pre-solar disk.

Spitzer Photometry of Approximately 1 Million Stars in M31 and 15 Other Galaxies

NASA Technical Reports Server (NTRS)

Khan, Rubab

2017-01-01

We present Spitzer IRAC 3.6-8 micrometer and Multiband Imaging Photometer 24 micrometer point-source catalogs for M31 and 15 other mostly large, star-forming galaxies at distances approximately 3.5-14 Mpc, including M51, M83, M101, and NGC 6946. These catalogs contain approximately 1 million sources including approximately 859,000 in M31 and approximately 116,000 in the other galaxies. They were created following the procedures described in Khan et al. through a combination of pointspread function (PSF) fitting and aperture photometry. These data products constitute a resource to improve our understanding of the IR-bright (3.6-24 micrometer) point-source populations in crowded extragalactic stellar fields and to plan observations with the James Webb Space Telescope.

40 CFR 471.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2013 CFR

2013-07-01

... CATEGORY Lead-Tin-Bismuth Forming Subcategory § 471.15 Pretreatment standards for new sources (PSNS... pretreatment standards for new sources. The mass of wastewater pollutants in lead-tin-bismuth forming process... (pounds per million off-pounds) of lead-tin-bismuth rolled with emulsions Antimony 0.067 0.030 Lead 0.010...

40 CFR 471.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2014 CFR

2014-07-01

... CATEGORY Lead-Tin-Bismuth Forming Subcategory § 471.15 Pretreatment standards for new sources (PSNS... pretreatment standards for new sources. The mass of wastewater pollutants in lead-tin-bismuth forming process... (pounds per million off-pounds) of lead-tin-bismuth rolled with emulsions Antimony 0.067 0.030 Lead 0.010...

40 CFR 471.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2010 CFR

2010-07-01

...-Tin-Bismuth Forming Subcategory § 471.15 Pretreatment standards for new sources (PSNS). Except as... standards for new sources. The mass of wastewater pollutants in lead-tin-bismuth forming process wastewater... million off-pounds) of lead-tin-bismuth rolled with emulsions Antimony 0.067 0.030 Lead 0.010 0.005 (b...

40 CFR 471.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2012 CFR

2012-07-01

... CATEGORY Lead-Tin-Bismuth Forming Subcategory § 471.15 Pretreatment standards for new sources (PSNS... pretreatment standards for new sources. The mass of wastewater pollutants in lead-tin-bismuth forming process... (pounds per million off-pounds) of lead-tin-bismuth rolled with emulsions Antimony 0.067 0.030 Lead 0.010...

40 CFR 471.15 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2011 CFR

2011-07-01

...-Tin-Bismuth Forming Subcategory § 471.15 Pretreatment standards for new sources (PSNS). Except as... standards for new sources. The mass of wastewater pollutants in lead-tin-bismuth forming process wastewater... million off-pounds) of lead-tin-bismuth rolled with emulsions Antimony 0.067 0.030 Lead 0.010 0.005 (b...

40 CFR 471.75 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2013 CFR

2013-07-01

... CATEGORY Uranium Forming Subcategory § 471.75 Pretreatment standards for new sources (PSNS). Except as... standards for new sources (PSNS). The mass of wastewater pollutants in uranium forming process wastewater... (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium 0.013 0.005 Copper 0.044...

40 CFR 471.75 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2014 CFR

2014-07-01

... CATEGORY Uranium Forming Subcategory § 471.75 Pretreatment standards for new sources (PSNS). Except as... standards for new sources (PSNS). The mass of wastewater pollutants in uranium forming process wastewater... (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium 0.013 0.005 Copper 0.044...

40 CFR 471.75 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2012 CFR

2012-07-01

... CATEGORY Uranium Forming Subcategory § 471.75 Pretreatment standards for new sources (PSNS). Except as... standards for new sources (PSNS). The mass of wastewater pollutants in uranium forming process wastewater... (pounds per million off-pounds) of uranium extruded Cadmium 0.007 0.003 Chromium 0.013 0.005 Copper 0.044...

Cassava as a food.

PubMed

Okezie, B O; Kosikowski, F V

1982-01-01

This review has attempted to examine information pertaining to the role of cassava (Manihot esculenta) as a major food source for a large part of the world population, particularly the countries of South America, Africa, and Asia, where it is primarily a major source of energy for 300 to 500 million people. Its cultivation, usually on small farms with little technology, is estimated to cover on an annual basis about 11 million hectares providing about 105 million tons, more than half of which is consumed by humans. The importance of cassava as an energy source can be seen by its growing demand in the European economic community countries where it forms up to 60% of the balanced diets for swine. Cassava is one of the crops that converts the greatest amount of solar energy into soluble carbohydrates per unit of area, thus 1 kg of moisture-free cassava meal may yield up to about 3750 kcal which would mean that a yearly production of 15 tons of cassava meal per hectare would yield some 56 million kcal. The major limitations of cassava as food appear to be its poor protein content and quality and the rapid post harvest deterioration of its roots which usually prevents their storage in the fresh state for more than a few days. However, in addition to its use for culinary purposes, cassava finds application in industrial products such as an adhesive for laundry purposes, for manufacturing paper, alcohol, butanol, dextrin, adhesive tape, textile sizing, and glue.

Ground-water withdrawals from the Coastal Plain of New Jersey, 1956-1980

USGS Publications Warehouse

Vowinkel, E.F.

1984-01-01

Withdrawals and site data for wells with a pump capacity of 100 ,000 gallons per day or greater in the Coastal Plain of New Jersey are stored in computer files for 1956-80. The data are aggregated by computer into tables, graphs and maps to show the distribution of ground-water withdrawals. Withdrawals are reported by type of use and aquifer for each county in the Coastal Plain. Public-supply wells withdraw the largest quantity of ground water in the Coastal Plain, followed by industrial and agricultural wells. In 1980 public-supply withdrawals were about 280 million gallons per day; the maximum monthly rate was about 355 million gallons per day in July, and the lowest was about 215 million gallons per day in February. Average industrial withdrawals were about 65 million gallons per day. Ground-water withdrawals used for agriculture vary significantly during the year. In 1980, about 75 percent of the agricultural withdrawals occurred from June through September. Several aquifers are used as sources of water supply in the Coastal Plain. Five regional aquifers are the major sources of water for public-supply, industrial, or agricultural use. In decreasing order of withdrawals in 1980, in million gallons per day, they are: The Potomac-Raritan-Magothy aquifer system, 243; Kirkwood-Cohansey aquifer system, 70; Atlantic City 800-foot sand, 21; Englishtown aquifer, 12; and the Wenonah-Mount Laurel aquifer system, 5. (USGS)

Apportionment of urban aerosol sources in Chongqing (China) using synergistic on-line techniques

NASA Astrophysics Data System (ADS)

Chen, Yang; Yang, Fumo

2016-04-01

The sources of ambient fine particulate matter (PM2.5) during wintertime at a background urban location in Chongqing (southwestern China) have been determined. Aerosol chemical composition analyses were performed using multiple on-line techniques, such as single particle aerosol mass spectrometer (SPAMS) for single particle chemical composition, on-line elemental carbon-organic carbon analyzer (on-line OC-EC), on-line X-ray fluorescence (XRF) for elements, and in-situ Gas and Aerosol Compositions monitor (IGAC) for water-soluble ions in PM2.5. All the datasets from these techniques have been adjusted to a 1-h time resolution for receptor model input. Positive matrix factorization (PMF) has been used for resolving aerosol sources. At least six sources, including domestic coal burning, biomass burning, dust, traffic, industrial and secondary/aged factors have been resolved and interpreted. The synergistic on-line techniques were helpful for identifying aerosol sources more clearly than when only employing the results from the individual techniques. This results are useful for better understanding of aerosol sources and atmospheric processes.

DNA methylation on N6-adenine in mammalian embryonic stem cells

PubMed Central

Wu, Tao P.; Wang, Tao; Seetin, Matthew G.; Lai, Yongquan; Zhu, Shijia; Lin, Kaixuan; Liu, Yifei; Byrum, Stephanie D.; Mackintosh, Samuel G.; Zhong, Mei; Tackett, Alan; Wang, Guilin; Hon, Lawrence S.; Fang, Gang; Swenberg, James A.; Xiao, Andrew Z.

2016-01-01

It has been widely accepted that 5-methylcytosine is the only form of DNA methylation in mammalian genomes. Here we identify N6-methyladenine as another form of DNA modification in mouse embryonic stem cells. Alkbh1 encodes a demethylase for N6-methyladenine. An increase of N6-methyladenine levels in Alkbh1-deficient cells leads to transcriptional silencing. N6-methyladenine deposition is inversely correlated with the evolutionary age of LINE-1 transposons; its deposition is strongly enriched at young (<1.5 million years old) but not old (>6 million years old) L1 elements. The deposition of N6-methyladenine correlates with epigenetic silencing of such LINE-1 transposons, together with their neighbouring enhancers and genes, thereby resisting the gene activation signals during embryonic stem cell differentiation. As young full-length LINE-1 transposons are strongly enriched on the X chromosome, genes located on the X chromosome are also silenced. Thus, N6-methyladenine developed a new role in epigenetic silencing in mammalian evolution distinct from its role in gene activation in other organisms. Our results demonstrate that N6-methyladenine constitutes a crucial component of the epigenetic regulation repertoire in mammalian genomes. PMID:27027282

Estimating large numbers.

PubMed

Landy, David; Silbert, Noah; Goldin, Aleah

2013-07-01

Despite their importance in public discourse, numbers in the range of 1 million to 1 trillion are notoriously difficult to understand. We examine magnitude estimation by adult Americans when placing large numbers on a number line and when qualitatively evaluating descriptions of imaginary geopolitical scenarios. Prior theoretical conceptions predict a log-to-linear shift: People will either place numbers linearly or will place numbers according to a compressive logarithmic or power-shaped function (Barth & Paladino, ; Siegler & Opfer, ). While about half of people did estimate numbers linearly over this range, nearly all the remaining participants placed 1 million approximately halfway between 1 thousand and 1 billion, but placed numbers linearly across each half, as though they believed that the number words "thousand, million, billion, trillion" constitute a uniformly spaced count list. Participants in this group also tended to be optimistic in evaluations of largely ineffective political strategies, relative to linear number-line placers. The results indicate that the surface structure of number words can heavily influence processes for dealing with numbers in this range, and it can amplify the possibility that analogous surface regularities are partially responsible for parallel phenomena in children. In addition, these results have direct implications for lawmakers and scientists hoping to communicate effectively with the public. Copyright © 2013 Cognitive Science Society, Inc.

Pain conditions ranked by healthcare costs for members of a national health plan.

PubMed

Pasquale, Margaret K; Dufour, Robert; Schaaf, David; Reiners, Andrew T; Mardekian, Jack; Joshi, Ashish V; Patel, Nick C

2014-02-01

Healthcare resource utilization (HCRU) and associated costs specific to pain are a growing concern, as increasing dollar amounts are spent on pain-related conditions. Understanding which pain conditions drive the highest utilization and cost burden to the healthcare system would enable providers and payers to better target conditions to manage pain adequately and efficiently. The current study focused on 36 noncancer chronic and 14 noncancer acute pain conditions and measured the HCRU and costs per member over 365 days. These conditions were ranked by per-member costs and total adjusted healthcare costs to determine the most expensive conditions to a national health plan. The top 5 conditions for the commercial line of business were back pain, osteoarthritis (OA), childbirth, injuries, and non-hip, non-spine fractures (adjusted annual total costs for the commercial members were $119 million, $98 million, $69 million, $61 million, and $48 million, respectively). The top 5 conditions for Medicare members were OA, back pain, hip fractures, injuries, and non-hip, non-spine fractures (adjusted annual costs for the Medicare members were $327 million, $218 million, $117 million, $82 million, and $67 million, respectively). The conditions ranked highest for both per-member and total healthcare costs were hip fractures, childbirth, and non-hip, non-spine fractures. Among these, hip fractures in the Medicare member population had the highest mean cost per member (adjusted per-member cost was $21,058). Further examination specific to how pain is managed in these high-cost conditions will enable providers and payers to develop strategies to improve patient outcomes through appropriate pain management. © 2013 Humana Inc. and Pfizer Inc. Pain Practice © 2013 World Institute of Pain.

“A Reduced-form Model to Estimate Near-road Air Quality for Communities: the Community Line Source modeling system (C-LINE)”

EPA Science Inventory

The paper presents the Community Line Source (C-LINE) modeling system that estimates toxic air pollutant (air toxics) concentration gradients within 500 meters of busy roadways for community-sized areas on the order of 100 km2. C-LINE accesses publicly available datasets with nat...

Shallow Refraction and Rg Analysis at the Source Physics Experiment Site

NASA Astrophysics Data System (ADS)

Rowe, C. A.; Carmichael, J. D.; Patton, H. J.; Snelson, C. M.; Coblentz, D. D.; Larmat, C. S.; Yang, X.

2014-12-01

We present analyses of the two-dimensional (2D) seismic structure beneath Source Physics Experiments (SPE) geophone lines that extended 100 to 2000 m from the source borehole with 100 m spacing. With seismic sources provided only at one end of the geophone lines, standard refraction profiling methods are unable to resolve the seismic velocity structures unambiguously. In previous work we have shown overall agreement between body-wave refraction modeling and Rg dispersion curves for the least complex of the five lines, Line 2, leading us to offer a simplified1D model for this line. A more detailed inspection of Line 2 supports a 2D re-interpretation of the structure on this line. We observe variation along the length of the line, as evidenced by abrupt and consistent changes in the behavior of surface waves at higher frequencies. We interpret this as a manifestation of significant material or structural heterogeneity in the shallowest strata. This interpretation is consistent with P-wave and Rg attenuation observations. Planned additional sources, both at the distal ends of the profiles and intermittently within their lengths, will provide significant enhancement to our ability to resolve this complicated shallow structure.

77 FR 58624 - ABE Fairmont, LLC-Acquisition and Operation Exemption-Fillmore Western Railway Company

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

... the line a number of years ago from FWRC for its private purposes under the mistaken belief that the... million. If the verified notice contains false or misleading information, the exemption is void ab initio...

Iran: U.S. Concerns and Policy Responses

DTIC Science & Technology

2008-01-30

family owns large share of Iran’s total pistachio nut production. President Mahmoud Ahmadinejad Leads faction of younger, harder line conservatives... pistachio nuts, carpets, medicines, artwork). Imports from U.S. — $85 million (food, medicines, tobacco products). Foreign Exchange $40 billion+ External

Iran: U.S. Concerns and Policy Responses

DTIC Science & Technology

2008-05-28

large share of Iran’s total pistachio nut production. President Mahmoud Ahmadinejad Leads faction of younger, harder line conservatives associated with...caviar, pistachio nuts, carpets, medicines, artwork). Imports from U.S. — $85 million (food, medicines, tobacco products). Foreign Exchange $40

Effecting IT infrastructure culture change: management by processes and metrics

NASA Technical Reports Server (NTRS)

Miller, R. L.

2001-01-01

This talk describes the processes and metrics used by Jet Propulsion Laboratory to bring about the required IT infrastructure culture change to update and certify, as Y2K compliant, thousands of computers and millions of lines of code.

Military Department Requirements for Currently Procured Wholesale Inventories for Consumable Items

DTIC Science & Technology

1991-06-28

The Military Departments have 13 major inventory control points (ICP’s) that provide logistics support to military customers to maximize the...Military Departments’ ICP’s managed approximately 1.1 million consumable line items for which wholesale inventories valued at $13.1 billion were held. In...August 1989, the ICP’s were in the process of procuring approximately $3.5 billion of stock for 77,650 consumable line items. The procurement process at

ETR COMPRESSOR BUILDING, TRA643. CAMERA FACES NORTH. AIR HEATERS LINE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

ETR COMPRESSOR BUILDING, TRA-643. CAMERA FACES NORTH. AIR HEATERS LINE UP AGAINST WALL, TO BE USED IN CONNECTION WITH ETR EXPERIMENTS. EACH HAD A HEAT OUTPUT OF 8 MILLION BTU PER HOUR, OPERATED AT 1260 DEGREES F. AND A PRESSURE OF 320 PSI. NOTE METAL WALLS AND ROOF. INL NEGATIVE NO. 56-3709. R.G. Larsen, Photographer, 11/13/1956 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

Geology and assessment of the undiscovered, technically recoverable petroleum resources of Armenia, 2013

USGS Publications Warehouse

Klett, T.R.

2016-02-23

The U.S. Geological Survey (USGS) assessed the undiscovered, technically recoverable oil and gas resources of Armenia in 2013. A Paleozoic and a Cenozoic total petroleum system (TPS) were identified within the country of Armenia. The postulated petroleum system elements are uncertain, resulting in low geologic probabilities for significant oil an gas resources. Two assessment units (AU) were delineated in each TPS—a Paleozoic-Sourced Conventional Reservoirs AU and a Permian Shale Gas AU in the Paleozoic Composite TPS and a Paleogene-Sourced Conventional Reservoirs AU and a Cenozoic Coalbed Gas AU in the Cenozoic Composite TPS. The TPS elements are largely uncertain and risked, and so only the Paleogene-Sourced Conventional Reservoirs AU was quantitatively assessed because the geologic probability is more than the threshold of 10 percent (that is, the probability of at least one conventional oil or gas accumulation of 5 million barrels of oil equivalent or greater based on postulated petroleum-system elements). The USGS estimated fully risked mean volumes of about 1 million barrels of oil (MMBO), about 6 billion cubic feet of natural gas (BCFG), and less than 1 million barrels of natural gas liquids (MMBNGL).

Status of timber utilization on the Pacific Coast.

Treesearch

John B. Grantham

1974-01-01

The need for additional sources of energy and raw material in the forest products industry enhances the opportunity to improve timber utilization by reducing logging residue. This is particularly true on the Pacific Coast where some 14 million tons of logging residue accumulate each year and where some 3 million tons of unused bark create a disposal problem at mills....

40 CFR 421.324 - Standards of performance for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

.../kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 27.14 11.00... average mg/kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 1.689 0... Chromium (total) 2.357 0.955 Copper 8.152 3.885 Nickel 3.503 2.357 Fluoride 222.900 126.700 Total suspended...

40 CFR 471.35 - Pretreatment standards for new sources (PSNS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... (pounds per million off-pounds) of nickel-cobalt rolled with emulsions Chromium 0.063 0.026 Nickel 0.094 0... nickel-cobalt rolled with water Chromium 0.028 0.012 Nickel 0.042 0.028 Fluoride 4.49 1.99 (d) Tube... monthly average mg/off-kg (pounds per million off-pounds) of nickel-cobalt drawn with emulsions Chromium 0...

40 CFR 421.324 - Standards of performance for new sources.

Code of Federal Regulations, 2010 CFR

2010-07-01

.../kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 27.14 11.00... average mg/kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 1.689 0... Chromium (total) 2.357 0.955 Copper 8.152 3.885 Nickel 3.503 2.357 Fluoride 222.900 126.700 Total suspended...

Basin-Wide Amazon Forest Tree Mortality From a Large 2005 Storm

NASA Astrophysics Data System (ADS)

Negron Juarez, R. I.; Chambers, J. Q.; Guimaraes, G.; Zeng, H.; Raupp, C.; Marra, D. M.; Ribeiro, G.; Saatchi, S. S.; Higuchi, N.

2010-12-01

Blowdowns are a recurrent characteristic of Amazon forests and are produced, among others, by squall lines. Squall lines are aligned clusters (typical length of 1000 km, width of 200 km) of deep convective cells that produce heavy rainfall during the dry season and significant rainfall during the wet season. These squall lines (accompanied by intense downbursts from convective cells) have been associated with large blowdowns characterized by uprooted, snapped trees, and trees being dragged down by other falling trees. Most squall lines in Amazonia form along the northeastern coast of South America as sea breeze-induced instability lines and propagate inside the continent. They occur frequently (~4 times per month), and can reach the central and even extreme western parts of Amazonia. Squall lines can also be generated inside the Amazon and propagate toward the equator. In January 2005 a squall line propagated from south to north across the entire Amazon basin producing widespread forest tree mortality and contributed to the elevated mortality observed that year. Over the Manaus region (3.4 x104 km2), disturbed forest patches generated by the squall produced a mortality of 0.3-0.5 million trees, equivalent to 30% of the observed annual deforestation reported in 2005 over the same area. The elevated mortality observed in the Central Amazon in 2005 is unlikely to be related to the 2005 Amazon drought since drought did not affect Central or Eastern Amazonia. Assuming a similar rate of forest mortality across the basin, the squall line could have potentially produced tree mortality estimated at 542 ± 121 million trees, equivalent to 23% of the mean annual biomass accumulation estimated for these forests. Our results highlight the vulnerability of Amazon trees to wind-driven mortality associated with convective storms. This vulnerability is likely to increase in a warming climate with models projecting an increase in storm intensity.

LSDCat: Detection and cataloguing of emission-line sources in integral-field spectroscopy datacubes

NASA Astrophysics Data System (ADS)

Herenz, Edmund Christian; Wisotzki, Lutz

2017-06-01

We present a robust, efficient, and user-friendly algorithm for detecting faint emission-line sources in large integral-field spectroscopic datacubes together with the public release of the software package Line Source Detection and Cataloguing (LSDCat). LSDCat uses a three-dimensional matched filter approach, combined with thresholding in signal-to-noise, to build a catalogue of individual line detections. In a second pass, the detected lines are grouped into distinct objects, and positions, spatial extents, and fluxes of the detected lines are determined. LSDCat requires only a small number of input parameters, and we provide guidelines for choosing appropriate values. The software is coded in Python and capable of processing very large datacubes in a short time. We verify the implementation with a source insertion and recovery experiment utilising a real datacube taken with the MUSE instrument at the ESO Very Large Telescope. The LSDCat software is available for download at http://muse-vlt.eu/science/tools and via the Astrophysics Source Code Library at http://ascl.net/1612.002

Water-use data by category, county, and water management district in Florida, 1950-90

USGS Publications Warehouse

Marella, R.L.

1995-01-01

The population for Florida in 1990 was estimated at 12.94 million, an increase of nearly 10.17 million (370 percent) from the population of 2.77 million in 1950. Consequently, water use (fresh and saline) in Florida increased nearly 510 percent (15,175 million gallons per day) between 1950 and 1990. The resident population of the State is projected to surpass 20 million by the year 2020. Through the cooperation of the Florida Department of Environ- mental Protection and the U.S. Geologial Survey, water-use data for the period between 1950 and 1990 has been consolidated into one publication. This report aggregates and summarizes the quantities of water withdrawn annually for all water-use categories (public supply, self-supplied domestic, self-supplied commercial-industrial, agriculture, and thermoelectric power generation), by counties, and water management districts in Florida from 1950 through 1990. Total water withdrawn in Florida increased from 2,923 million gallons per day in 1950 to 17,898 million gallons per day in 1990. Surface- water withdrawals during 1950 totaled 2,333 million gallons per day but were not differentiated between fresh and saline, therefore, comparisons between fresh and saline water were made beginning with 1955 data. Freshwater withdrawals increased 245 percent between 1955 and 1990. Saline water withdrawals increased more than 1,500 percent between 1955 and 1990. In 1955, more than 47 percent of the fresh- water used was withdrawn from ground-water sources and 53 percent was withdrawn from surface-water sources. In 1990, nearly 62 percent of the fresh- water withdrawn was from ground-water sources, while 38 percent was withdrawn from surface-water sources. The steady increase in ground-water withdrawals since the 1950's primarily is a result of the ability to drill and pump water more economically from large, deep wells and the reliability of both the quality and quantity of water from these wells. Water withdrawn for public supply in Florida increased 1,030 percent between 1950 and 1990. The population served by public supply increased from 1.66 million in 1950 to 11.23 million in 1990, and the percentage of the population served by public supply increased from 60 percent in 1950 to nearly 88 percent in 1990. Freshwater withdrawn for self- supplied domestic use in Florida increased 1,010 percent, self-supplied commercial-industrial uses increased 170 percent, and agriculture increased 915 percent between 1950 and 1990. Freshwater with- drawals for thermoelectric power generation decreased 8 percent between 1955 and 1990, while saline water withdrawals increased nearly 1,540 percent between 1955 and 1990. Between 1965 and 1990, total freshwater withdrawals increased in 58 of the 67 counties in Florida. Fresh ground-water was withdrawn in all 67 counties in 1965 through 1990, and increased in 65 counties between 1965 and 1990. Fresh surface-water was withdrawn in 60 counties from 1965 to 1990, and increased in 42 counties between 1965 and 1990. The change in total freshwater withdrawals within the water management districts between 1975 and 1990 were as follows: Northwest Florida Water Management District increased 3 percent, St. Johns River Water Management District decreased 6 percent, South Florida Water Management District increased 37 percent, Southwest Florida Water Management District decreased 1 percent, and Suwannee River Water Management District increased 8 percent.(USGS)

Estimated water and nutrient inflows and outflows, Lake Cochituate, eastern Massachusetts, 1977-79

USGS Publications Warehouse

Gay, F.B.

1984-01-01

Streamflow was the major source of water and nutrients (nitrogen and phosphorus) to Lake Cochituate, followed by ground water, and then precipitation during April 1978 through March 1979. Compared to all sources during that period, streams contributed 7,217 million gallons (a little over 82 percent) of water, 63 ,000 pounds (between 50 and 60 percent) of nitrogen, and 3,000 pounds (94 percent) of phosphorus. A little over 60 percent of all the water that entered Lake Cochituate flowed from Fisk Pond. This single source transported about 38,000 pounds of nitrogen and 2,000 pounds of phosphorus. Ground-water inflow to Lake Cochituate occurs along its shoreline except at the north end of Lake Cochituate 's North Pond where natural seepage from the lake is occurring and at locations on the lake 's Middle and South Ponds where municipal wells induce infiltration of lake water amounting to 1,228 million gallons for that period. Discharge of ground water to the lake was estimated to range from 462 to 816 million gallons and transported from 31,000 to 55,000 pounds of nitrogen and from 46 to 82 pounds of phosphorus. Bulk precipitation was estimated to contribute about the same volume of water to the lake as ground water but double its phosphorus load. However, the load of nitrogen, 8000 pounds, from bulk precipitation was the smallest of any source. (USGS)

Community LINE Source Model (C-LINE)

EPA Science Inventory

This presentation provides an introduction for the live demo and explains the purpose of C-LINE and its key features. C-LINE is a web-based model designed to inform the community user of local air quality impacts due to mobile-sources in their region of interest using a simplifie...

Selected approaches to estimate water-budget components of the High Plains, 1940 through 1949 and 2000 through 2009

USGS Publications Warehouse

Stanton, Jennifer S.; Qi, Sharon L.; Ryter, Derek W.; Falk, Sarah E.; Houston, Natalie A.; Peterson, Steven M.; Westenbroek, Stephen M.; Christenson, Scott C.

2011-01-01

The High Plains aquifer, underlying almost 112 million acres in the central United States, is one of the largest aquifers in the Nation. It is the primary water supply for drinking water, irrigation, animal production, and industry in the region. Expansion of irrigated agriculture throughout the past 60 years has helped make the High Plains one of the most productive agricultural regions in the Nation. Extensive withdrawals of groundwater for irrigation have caused water-level declines in many parts of the aquifer and increased concerns about the long-term sustainability of the aquifer. Quantification of water-budget components is a prerequisite for effective water-resources management. Components analyzed as part of this study were precipitation, evapotranspiration, recharge, surface runoff, groundwater discharge to streams, groundwater fluxes to and from adjacent geologic units, irrigation, and groundwater in storage. These components were assessed for 1940 through 1949 (representing conditions prior to substantial groundwater development and referred to as "pregroundwater development" throughout this report) and 2000 through 2009. Because no single method can perfectly quantify the magnitude of any part of a water budget at a regional scale, results from several methods and previously published work were compiled and compared for this study when feasible. Results varied among the several methods applied, as indicated by the range of average annual volumes given for each component listed in the following paragraphs. Precipitation was derived from three sources: the Parameter-Elevation Regressions on Independent Slopes Model, data developed using Next Generation Weather Radar and measured precipitation from weather stations by the Office of Hydrologic Development at the National Weather Service for the Sacramento-Soil Moisture Accounting model, and precipitation measured at weather stations and spatially distributed using an inverse-distance-weighted interpolation method. Precipitation estimates using these sources, as a 10-year average annual total volume for the High Plains, ranged from 192 to 199 million acre-feet (acre-ft) for 1940 through 1949 and from 185 to 199 million acre-ft for 2000 through 2009. Evapotranspiration was obtained from three sources: the National Weather Service Sacramento-Soil Moisture Accounting model, the Simplified-Surface-Energy-Balance model using remotely sensed data, and the Soil-Water-Balance model. Average annual total evapotranspiration estimated using these sources was 148 million acre-ft for 1940 through 1949 and ranged from 154 to 193 million acre-ft for 2000 through 2009. The maximum amount of shallow groundwater lost to evapotranspiration was approximated for areas where the water table was within 5 feet of land surface. The average annual total volume of evapotranspiration from shallow groundwater was 9.0 million acre-ft for 1940 through 1949 and ranged from 9.6 to 12.6 million acre-ft for 2000 through 2009. Recharge was estimated using two soil-water-balance models as well as previously published studies for various locations across the High Plains region. Average annual total recharge ranged from 8.3 to 13.2 million acre-ft for 1940 through 1949 and from 15.9 to 35.0 million acre-ft for 2000 through 2009. Surface runoff and groundwater discharge to streams were determined using discharge records from streamflow-gaging stations near the edges of the High Plains and the Base-Flow Index program. For 1940 through 1949, the average annual net surface runoff leaving the High Plains was 1.9 million acre-ft, and the net loss from the High Plains aquifer by groundwater discharge to streams was 3.1 million acre-ft. For 2000 through 2009, the average annual net surface runoff leaving the High Plains region was 1.3 million acre-ft and the net loss by groundwater discharge to streams was 3.9 million acre-ft. For 2000 through 2009, the average annual total estimated groundwater pumpage volume from two soil-water-balance models ranged from 8.7 to 16.2 million acre-ft. Average annual irrigation application rates for the High Plains ranged from 8.4 to 16.2 inches per year. The USGS Water-Use Program published estimated total annual pumpage from the High Plains aquifer for 2000 and 2005. Those volumes were greater than those estimated from the two soil-water-balance models. Total groundwater in storage in the High Plains aquifer was estimated as 3,173 million acre-ft prior to groundwater development and 2,907 million acre-ft in 2007. The average annual decrease of groundwater in storage between 2000 and 2007 was 10 million acre-ft per year.

76 FR 58150 - Defense Federal Acquisition Regulations Supplement; Discussions Prior to Contract Award (DFARS...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

... discussions prior to award for source selections of procurements estimated at $100 million or more. DATES... 24, 2010, to implement the recommendation of the DoD Source Selection Joint Analysis Team (JAT) to... negative effects, such as added Government and industry cost due to the significant increase in the source...

2MASS Extended Source Catalog: Overview and Algorithms

NASA Technical Reports Server (NTRS)

Jarrett, T.; Chester, T.; Cutri, R.; Schneider, S.; Skrutskie, M.; Huchra, J.

1999-01-01

The 2 Micron All-Sky Survey (2MASS)will observe over one-million galaxies and extended Galactic sources covering the entire sky at wavelenghts between 1 and 2 m. Most of these galaxies, from 70 to 80%, will be newly catalogued objetcs.

Development of a transportable neutron activation analysis system to quantify manganese in bone in vivo: feasibility and methodology.

PubMed

Liu, Yingzi; Koltick, David; Byrne, Patrick; Wang, Haoyu; Zheng, Wei; Nie, Linda H

2013-12-01

This study was conducted to investigate the methodology and feasibility of developing a transportable neutron activation analysis (NAA) system to quantify manganese (Mn) in bone using a portable deuterium-deuterium (DD) neutron generator as the neutron source. Since a DD neutron generator was not available in our laboratory, a deuterium-tritium (DT) neutron generator was used to obtain experimental data and validate the results from Monte Carlo (MC) simulations. After validation, MC simulations using a DD generator as the neutron source were then conducted. Different types of moderators and reflectors were simulated, and the optimal thicknesses for the moderator and reflector were determined. To estimate the detection limit (DL) of the system, and to observe the interference of the magnesium (Mg) γ line at 844 keV to the Mn γ line at 847 keV, three hand phantoms with Mn concentrations of 30 parts per million (ppm), 150 ppm, and 500 ppm were made and irradiated by the DT generator system. The Mn signals in these phantoms were then measured using a 50% high-efficiency high-purity germanium (HPGe) detector. The DL was calculated to be about 4.4 ppm for the chosen irradiation, decay, and measurement time. This was calculated to be equivalent to a DL of about 3.3 ppm for the DD generator system. To achieve this DL with one 50% high-efficiency HPGe detector, the dose to the hand was simulated to be about 37 mSv, with the total body equivalent dose being about 23µSv. In conclusion, it is feasible to develop a transportable NAA system to quantify Mn in bone in vivo with an acceptable radiation exposure to the subject.

Development of a transportable neutron activation analysis system to quantify manganese in bone in vivo: feasibility and methodology

PubMed Central

Liu, Yingzi; Koltick, David; Byrne, Patrick; Wang, Haoyu; Zheng, Wei; Nie, Linda H

2014-01-01

This study was conducted to investigate the methodology and feasibility of developing a transportable neutron activation analysis (NAA) system to quantify manganese (Mn) in bone using a portable deuterium–deuterium (DD) neutron generator as the neutron source. Since a DD neutron generator was not available in our laboratory, a deuterium–tritium (DT) neutron generator was used to obtain experimental data and validate the results from Monte Carlo (MC) simulations. After validation, MC simulations using a DD generator as the neutron source were then conducted. Different types of moderators and reflectors were simulated, and the optimal thicknesses for the moderator and reflector were determined. To estimate the detection limit (DL) of the system, and to observe the interference of the magnesium (Mg) γ line at 844 keV to the Mn γ line at 847 keV, three hand phantoms with Mn concentrations of 30 parts per million (ppm), 150 ppm, and 500 ppm were made and irradiated by the DT generator system. The Mn signals in these phantoms were then measured using a 50% high-efficiency high-purity germanium (HPGe) detector. The DL was calculated to be about 4.4 ppm for the chosen irradiation, decay, and measurement time. This was calculated to be equivalent to a DL of about 3.3 ppm for the DD generator system. To achieve this DL with one 50% high-efficiency HPGe detector, the dose to the hand was simulated to be about 37 mSv, with the total body equivalent dose being about 23μSv. In conclusion, it is feasible to develop a transportable NAA system to quantify Mn in bone in vivo with an acceptable radiation exposure to the subject. PMID:24165395

Detailed Velocity and Density models of the Cascadia Subduction Zone from Prestack Full-Waveform Inversion

NASA Astrophysics Data System (ADS)

Fortin, W.; Holbrook, W. S.; Mallick, S.; Everson, E. D.; Tobin, H. J.; Keranen, K. M.

2014-12-01

Understanding the geologic composition of the Cascadia Subduction Zone (CSZ) is critically important in assessing seismic hazards in the Pacific Northwest. Despite being a potential earthquake and tsunami threat to millions of people, key details of the structure and fault mechanisms remain poorly understood in the CSZ. In particular, the position and character of the subduction interface remains elusive due to its relative aseismicity and low seismic reflectivity, making imaging difficult for both passive and active source methods. Modern active-source reflection seismic data acquired as part of the COAST project in 2012 provide an opportunity to study the transition from the Cascadia basin, across the deformation front, and into the accretionary prism. Coupled with advances in seismic inversion methods, this new data allow us to produce detailed velocity models of the CSZ and accurate pre-stack depth migrations for studying geologic structure. While still computationally expensive, current computing clusters can perform seismic inversions at resolutions that match that of the seismic image itself. Here we present pre-stack full waveform inversions of the central seismic line of the COAST survey offshore Washington state. The resultant velocity model is produced by inversion at every CMP location, 6.25 m laterally, with vertical resolution of 0.2 times the dominant seismic frequency. We report a good average correlation value above 0.8 across the entire seismic line, determined by comparing synthetic gathers to the real pre-stack gathers. These detailed velocity models, both Vp and Vs, along with the density model, are a necessary step toward a detailed porosity cross section to be used to determine the role of fluids in the CSZ. Additionally, the P-velocity model is used to produce a pre-stack depth migration image of the CSZ.

Class 1 railroad statistics, 2010

DOT National Transportation Integrated Search

2010-05-24

U.S. Class I Railroads are line haul freight railroads with 2008 operating revenue in excess of $401.4 million. Two Canadian railroads, CN and Canadian Pacific, have enough revenue that they would be U.S. Class I railroads if they were U.S. companies...

BIOFILM IN DRINKING WATER DISTRIBUTION SYSTEMS

EPA Science Inventory

Throughout the world there are millions of miles of water distribution pipe lines which provide potable water for use by individuals and industry. Some of these water distribution systems have been in service well over one hundred years. Treated water moving through a distributio...

Uncovering the Secret of Shock Wave Lithotripsy

NASA Astrophysics Data System (ADS)

Zhong, P.

Shock wave lithotripsy (SWL) is an engineering innovation that has revolutionized the treatment of kidney stone disease since the early 1980s [1] - [3]. Today, SWL is the first-line therapy for millions of patients worldwide with renal and upper urinary stones [3, 4].

[Random Variable Read Me File

NASA Technical Reports Server (NTRS)

Teubert, Christopher; Sankararaman, Shankar; Cullo, Aiden

2017-01-01

Readme for the Random Variable Toolbox usable manner. is a Web-based Git version control repository hosting service. It is mostly used for computer code. It offers all of the distributed version control and source code management (SCM) functionality of Git as well as adding its own features. It provides access control and several collaboration features such as bug tracking, feature requests, task management, and wikis for every project.[3] GitHub offers both plans for private and free repositories on the same account[4] which are commonly used to host open-source software projects.[5] As of April 2017, GitHub reports having almost 20 million users and 57 million repositories,[6] making it the largest host of source code in the world.[7] GitHub has a mascot called Octocat, a cat with five tentacles and a human-like face

Method and apparatus for reducing the harmonic currents in alternating-current distribution networks

DOEpatents

Beverly, Leon H.; Hance, Richard D.; Kristalinski, Alexandr L.; Visser, Age T.

1996-01-01

An improved apparatus and method reduce the harmonic content of AC line and neutral line currents in polyphase AC source distribution networks. The apparatus and method employ a polyphase Zig-Zag transformer connected between the AC source distribution network and a load. The apparatus and method also employs a mechanism for increasing the source neutral impedance of the AC source distribution network. This mechanism can consist of a choke installed in the neutral line between the AC source and the Zig-Zag transformer.

Method and apparatus for reducing the harmonic currents in alternating-current distribution networks

DOEpatents

Beverly, L.H.; Hance, R.D.; Kristalinski, A.L.; Visser, A.T.

1996-11-19

An improved apparatus and method reduce the harmonic content of AC line and neutral line currents in polyphase AC source distribution networks. The apparatus and method employ a polyphase Zig-Zag transformer connected between the AC source distribution network and a load. The apparatus and method also employs a mechanism for increasing the source neutral impedance of the AC source distribution network. This mechanism can consist of a choke installed in the neutral line between the AC source and the Zig-Zag transformer. 23 figs.

Sugar and Other Sweeteners

NASA Astrophysics Data System (ADS)

Godshall, Mary An

Sugar and starch are among the most abundant plant products available, and large industries exist worldwide to extract and process them from agricultural sources. The world production of sugar (sucrose from cane and beet) in 2004/2005 was 142 million metric tons, raw value, 1 with 24.8 percent of that being beet sugar and 75.1 percent being cane sugar.2 The proportion of beet sugar to cane sugar has fallen steadily since about 1971, when it constituted 42.8 percent of total sugar production. The decline in total beet sugar proportion over the last ten years represents not so much a decline in beet production, which has remained in a range of 33-39 million metric tons, but rather a continued increase in cane sugar production from around 70 million metric tons in 1991 to 112 million metric tons.2 The production of total world sugar has also risen dramatically since 1971/72, when it was 71.7 million tons.3

Line-source simulation for shallow-seismic data. Part 2: full-waveform inversion—a synthetic 2-D case study

NASA Astrophysics Data System (ADS)

Schäfer, M.; Groos, L.; Forbriger, T.; Bohlen, T.

2014-09-01

Full-waveform inversion (FWI) of shallow-seismic surface waves is able to reconstruct lateral variations of subsurface elastic properties. Line-source simulation for point-source data is required when applying algorithms of 2-D adjoint FWI to recorded shallow-seismic field data. The equivalent line-source response for point-source data can be obtained by convolving the waveforms with √{t^{-1}} (t: traveltime), which produces a phase shift of π/4. Subsequently an amplitude correction must be applied. In this work we recommend to scale the seismograms with √{2 r v_ph} at small receiver offsets r, where vph is the phase velocity, and gradually shift to applying a √{t^{-1}} time-domain taper and scaling the waveforms with r√{2} for larger receiver offsets r. We call this the hybrid transformation which is adapted for direct body and Rayleigh waves and demonstrate its outstanding performance on a 2-D heterogeneous structure. The fit of the phases as well as the amplitudes for all shot locations and components (vertical and radial) is excellent with respect to the reference line-source data. An approach for 1-D media based on Fourier-Bessel integral transformation generates strong artefacts for waves produced by 2-D structures. The theoretical background for both approaches is presented in a companion contribution. In the current contribution we study their performance when applied to waves propagating in a significantly 2-D-heterogeneous structure. We calculate synthetic seismograms for 2-D structure for line sources as well as point sources. Line-source simulations obtained from the point-source seismograms through different approaches are then compared to the corresponding line-source reference waveforms. Although being derived by approximation the hybrid transformation performs excellently except for explicitly back-scattered waves. In reconstruction tests we further invert point-source synthetic seismograms by a 2-D FWI to subsurface structure and evaluate its ability to reproduce the original structural model in comparison to the inversion of line-source synthetic data. Even when applying no explicit correction to the point-source waveforms prior to inversion only moderate artefacts appear in the results. However, the overall performance is best in terms of model reproduction and ability to reproduce the original data in a 3-D simulation if inverted waveforms are obtained by the hybrid transformation.

STUDIES ON MAMMALIAN AND HUMAN PYRUVATE AND ALPHA-KETOGLUTARATE DEHYDROGENATION COMPLEXES.

DTIC Science & Technology

The pig heart pyruvate and alpha - ketoglutarate dehydrogenase complex were isolated in highly purified state as multienzyme units with molecular...weights of approximately 9 million and 2.8 million, respectively. The aims were to resolve the pig heart pyruvate and alpha - ketoglutarate dehydrogenase...complexes was isolated from three sources; (1) pyruvate dehydrogenase complex, (2) alpha - ketoglutarate dehydrogenase, and (3) amber-color extract free

Rural Land Use: Patterns and Proposals for Reform.

ERIC Educational Resources Information Center

Erickson, Ronald P.

In a world where the population is increasing at an annual rate of 76 million, where food is in short supply, and where agricultural production is one of our largest capital generating sources, U.S. agriculture and the land base supporting it are vital. Rural America has been losing land at a rate of one and a half million acres a year due to soil…

40 CFR 471.93 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... monthly average mg/off-kg (pounds per million off-pounds) of zirconium-hafnium extruded Chromium 0.104 0... monthly average mg/off-kg (pounds per million off-pounds) of zirconium-hafnium heat treated Chromium 0.015... Chromium 0.150 0.061 Cyanide 0.099 0.041 Nickel 0.653 0.432 Ammonia 45.3 20.0 Fluoride 20.0 8.98 Oil and...

40 CFR 471.93 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... monthly average mg/off-kg (pounds per million off-pounds) of zirconium-hafnium extruded Chromium 0.104 0... monthly average mg/off-kg (pounds per million off-pounds) of zirconium-hafnium heat treated Chromium 0.015... Chromium 0.150 0.061 Cyanide 0.099 0.041 Nickel 0.653 0.432 Ammonia 45.3 20.0 Fluoride 20.0 8.98 Oil and...

Seniors in Cyberspace. Trends and Issues Alerts.

ERIC Educational Resources Information Center

Imel, Susan

Approximately 15% (7.6 million) of the estimated 50.6 million U.S. citizens who browse the World Wide Web are aged 50 or older, and 30% of adults aged 55-75 own a computer. Although many older adults initially log on to the Internet as a means of connecting with friends and family, they quickly learn that it is also a valuable source of…

76 FR 80531 - National Emission Standards for Hazardous Air Pollutants for Area Sources: Industrial, Commercial...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-23

... boilers are small (less than 10 MMBtu/hr heat input) and are generally owned and operated by contractors... (> 5MMBtu/h) or five-year ( New boilers with heat input capacity greater than 10 million Btu per hour that... with heat input capacity greater than 10 million Btu per hour that are biomass-fired or oil-fired must...

BC International Student Revenue Grows Again. BCTF Research Report. Section V. 2012-EF-02

ERIC Educational Resources Information Center

Kuehn, Larry

2011-01-01

After two years of decline, the tuition from international students increased in 2010-11 and reached more than $129 million. The revenue from international students has more than doubled in a decade, from $55.5 million in 2001-02. This revenue is the most significant source of funding for K-12 education in BC outside of direct grants from the…

40 CFR 467.35 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... extruded Chromium 0.15 0.061 Cyanide 0.098 0.041 Zinc 0.49 0.21 TTO 0.23 Oil and grease (alternate... for any 1 day Maximum for monthly average mg/off-kg (lb/million off-lbs) of extruded Chromium 0.65 0... 1 day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum cast Chromium 0.59 0.24...

Carbon and oxygen X-ray line emission from the interstellar medium

NASA Technical Reports Server (NTRS)

Schnopper, H. W.; Delvaille, J. P.; Rocchia, R.; Blondel, C.; Cheron, C.; Christy, J. C.; Ducros, R.; Koch, L.; Rothenflug, R.

1982-01-01

A soft X-ray, 0.3-1.0 keV spectrum from a 1 sr region which includes a portion of the North Polar Spur, obtained by three rocketborne lithium-drifted silicon detectors, shows the C V, C VI, O VII and O VIII emission lines. The spectrum is well fitted by a two-component, modified Kato (1976) model, where the coronal emission is in collisional equilibrium, with interstellar medium and North Polar Spur temperatures of 1.1 and 3.8 million K, respectively.

Ballet of Loops

NASA Image and Video Library

2018-06-11

Giant, bright coronal loops trace out the magnetic field lines above an active region from June 4-6, 2018. The wavelength of extreme ultraviolet light shown here is emitted by ionized iron travelling along the field lines, super-heated to approximately 1 million degrees K. Coronal loops were not seen in this level of detail until the Solar Dynamics Observatory was launched in 2010 and came online, giving solar scientists new data with which to study the Sun and its processes. https://photojournal.jpl.nasa.gov/catalog/PIA22508

Introduction to the Security Engineering Risk Analysis (SERA) Framework

DTIC Science & Technology

2014-11-01

military aircraft has increased from 8% to 80%. At the same time, the size of software in military aircraft has grown from 1,000 lines of code in the F...4A to 1.7 million lines of code in the F-22. This growth trend is expected to con- tinue over time [NASA 2009]. As software exerts more control of...their root causes can be traced to the software’s requirements, architecture, design, or code . Studies have shown that the cost of addressing a software

Software ``Best'' Practices: Agile Deconstructed

NASA Astrophysics Data System (ADS)

Fraser, Steven

This workshop will explore the intersection of agility and software development in a world of legacy code-bases and large teams. Organizations with hundreds of developers and code-bases exceeding a million or tens of millions of lines of code are seeking new ways to expedite development while retaining and attracting staff who desire to apply “agile” methods. This is a situation where specific agile practices may be embraced outside of their usual zone of applicability. Here is where practitioners must understand both what “best practices” already exist in the organization - and how they might be improved or modified by applying “agile” approaches.

WMATA (Washington Metropolitan Area Transit Authority) 1985 annual report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-12-31

Ridership continues to grow with 210.9 million trips taken during calendar year 1985. The Red Line from Van Ness-UDC to Shady Grove opened in late 1984 and helped stimulate the growth. Meanwhile, construction gets underway on the Green Line with groundbreakings at Anacostia and West Hyattsville stations. The Board approves the Green Line alignment between Columbia Heights and Fort Totten, ending years of discussion and study. Report's feature articles deal with preventive maintenance, the need to finish building the 103-mile system, safety, Metro-related development and the five-year capital improvement plan. The report contains eight pages of financial statements.

Documentation of input datasets for the soil-water balance groundwater recharge model of the Upper Colorado River Basin

USGS Publications Warehouse

Tillman, Fred D.

2015-01-01

The Colorado River and its tributaries supply water to more than 35 million people in the United States and 3 million people in Mexico, irrigating more than 4.5 million acres of farmland, and generating about 12 billion kilowatt hours of hydroelectric power annually. The Upper Colorado River Basin, encompassing more than 110,000 square miles (mi2), contains the headwaters of the Colorado River (also known as the River) and is an important source of snowmelt runoff to the River. Groundwater discharge also is an important source of water in the River and its tributaries, with estimates ranging from 21 to 58 percent of streamflow in the upper basin. Planning for the sustainable management of the Colorado River in future climates requires an understanding of the Upper Colorado River Basin groundwater system. This report documents input datasets for a Soil-Water Balance groundwater recharge model that was developed for the Upper Colorado River Basin.

History of Chandra X-Ray Observatory

NASA Image and Video Library

1999-12-01

This Chandra image shows the central regions of two colliding galaxies known collectively as the Antennae (NGC-4038/4039). The Chandra image reveals a large population of extremely bright x-ray sources in this area of intense star formation. These x-ray sources, which emit 10 to several hundred times more x-ray power than similar sources in our own galaxy, are believed to be either massive black holes, or black holes that are beaming their energy toward Earth. In this x-ray image, red represents the low energy band, green intermediate, and blue the highest observed energies. The white and yellow sources are those that emit significant amounts of both low and high energy x-rays. About 60 million light years from Earth in the constellation Corvus, the Antennae Galaxies got their nickname from the wispy anntennae-like streams of gas as seen by optical telescopes. These ongoing wisps are believed to have been produced approximately 100 million years ago by the collision between the gala

Inselect: Automating the Digitization of Natural History Collections

PubMed Central

Hudson, Lawrence N.; Blagoderov, Vladimir; Heaton, Alice; Holtzhausen, Pieter; Livermore, Laurence; Price, Benjamin W.; van der Walt, Stéfan; Smith, Vincent S.

2015-01-01

The world’s natural history collections constitute an enormous evidence base for scientific research on the natural world. To facilitate these studies and improve access to collections, many organisations are embarking on major programmes of digitization. This requires automated approaches to mass-digitization that support rapid imaging of specimens and associated data capture, in order to process the tens of millions of specimens common to most natural history collections. In this paper we present Inselect—a modular, easy-to-use, cross-platform suite of open-source software tools that supports the semi-automated processing of specimen images generated by natural history digitization programmes. The software is made up of a Windows, Mac OS X, and Linux desktop application, together with command-line tools that are designed for unattended operation on batches of images. Blending image visualisation algorithms that automatically recognise specimens together with workflows to support post-processing tasks such as barcode reading, label transcription and metadata capture, Inselect fills a critical gap to increase the rate of specimen digitization. PMID:26599208

Inselect: Automating the Digitization of Natural History Collections.

PubMed

Hudson, Lawrence N; Blagoderov, Vladimir; Heaton, Alice; Holtzhausen, Pieter; Livermore, Laurence; Price, Benjamin W; van der Walt, Stéfan; Smith, Vincent S

2015-01-01

The world's natural history collections constitute an enormous evidence base for scientific research on the natural world. To facilitate these studies and improve access to collections, many organisations are embarking on major programmes of digitization. This requires automated approaches to mass-digitization that support rapid imaging of specimens and associated data capture, in order to process the tens of millions of specimens common to most natural history collections. In this paper we present Inselect-a modular, easy-to-use, cross-platform suite of open-source software tools that supports the semi-automated processing of specimen images generated by natural history digitization programmes. The software is made up of a Windows, Mac OS X, and Linux desktop application, together with command-line tools that are designed for unattended operation on batches of images. Blending image visualisation algorithms that automatically recognise specimens together with workflows to support post-processing tasks such as barcode reading, label transcription and metadata capture, Inselect fills a critical gap to increase the rate of specimen digitization.

Landscape of genomic diversity and trait discovery in soybean.

PubMed

Valliyodan, Babu; Dan Qiu; Patil, Gunvant; Zeng, Peng; Huang, Jiaying; Dai, Lu; Chen, Chengxuan; Li, Yanjun; Joshi, Trupti; Song, Li; Vuong, Tri D; Musket, Theresa A; Xu, Dong; Shannon, J Grover; Shifeng, Cheng; Liu, Xin; Nguyen, Henry T

2016-03-31

Cultivated soybean [Glycine max (L.) Merr.] is a primary source of vegetable oil and protein. We report a landscape analysis of genome-wide genetic variation and an association study of major domestication and agronomic traits in soybean. A total of 106 soybean genomes representing wild, landraces, and elite lines were re-sequenced at an average of 17x depth with a 97.5% coverage. Over 10 million high-quality SNPs were discovered, and 35.34% of these have not been previously reported. Additionally, 159 putative domestication sweeps were identified, which includes 54.34 Mbp (4.9%) and 4,414 genes; 146 regions were involved in artificial selection during domestication. A genome-wide association study of major traits including oil and protein content, salinity, and domestication traits resulted in the discovery of novel alleles. Genomic information from this study provides a valuable resource for understanding soybean genome structure and evolution, and can also facilitate trait dissection leading to sequencing-based molecular breeding.

Landscape of genomic diversity and trait discovery in soybean

PubMed Central

Valliyodan, Babu; Dan Qiu; Patil, Gunvant; Zeng, Peng; Huang, Jiaying; Dai, Lu; Chen, Chengxuan; Li, Yanjun; Joshi, Trupti; Song, Li; Vuong, Tri D.; Musket, Theresa A.; Xu, Dong; Shannon, J. Grover; Shifeng, Cheng; Liu, Xin; Nguyen, Henry T.

2016-01-01

Cultivated soybean [Glycine max (L.) Merr.] is a primary source of vegetable oil and protein. We report a landscape analysis of genome-wide genetic variation and an association study of major domestication and agronomic traits in soybean. A total of 106 soybean genomes representing wild, landraces, and elite lines were re-sequenced at an average of 17x depth with a 97.5% coverage. Over 10 million high-quality SNPs were discovered, and 35.34% of these have not been previously reported. Additionally, 159 putative domestication sweeps were identified, which includes 54.34 Mbp (4.9%) and 4,414 genes; 146 regions were involved in artificial selection during domestication. A genome-wide association study of major traits including oil and protein content, salinity, and domestication traits resulted in the discovery of novel alleles. Genomic information from this study provides a valuable resource for understanding soybean genome structure and evolution, and can also facilitate trait dissection leading to sequencing-based molecular breeding. PMID:27029319

THE CORES OF THE Fe K{alpha} LINES IN ACTIVE GALACTIC NUCLEI: AN EXTENDED CHANDRA HIGH ENERGY GRATING SAMPLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shu, X. W.; Wang, J. X.; Yaqoob, T.

We extend the study of the core of the Fe K{alpha} emission line at {approx}6.4 keV in Seyfert galaxies reported by Yaqoob and Padmanabhan using a larger sample observed by the Chandra high-energy grating (HEG). The sample consists of 82 observations of 36 unique sources with z < 0.3. Whilst heavily obscured active galactic nuclei are excluded from the sample, these data offer some of the highest precision measurements of the peak energy of the Fe K{alpha} line, and the highest spectral resolution measurements of the width of the core of the line in unobscured and moderately obscured (N {submore » H} < 10{sup 23} cm{sup -2}) Seyfert galaxies to date. From an empirical and uniform analysis, we present measurements of the Fe K{alpha} line centroid energy, flux, equivalent width (EW), and intrinsic width (FWHM). The Fe K{alpha} line is detected in 33 sources, and its centroid energy is constrained in 32 sources. In 27 sources, the statistical quality of the data is good enough to yield measurements of the FWHM. We find that the distribution in the line centroid energy is strongly peaked around the value for neutral Fe, with over 80% of the observations giving values in the range 6.38-6.43 keV. Including statistical errors, 30 out of 32 sources ({approx}94%) have a line centroid energy in the range 6.35-6.47 keV. The mean EW, among the observations in which a non-zero lower limit could be measured, was 53 {+-} 3 eV. The mean FWHM from the subsample of 27 sources was 2060 {+-} 230 km s{sup -1}. The mean EW and FWHM are somewhat higher when multiple observations for a given source are averaged. From a comparison with the H{beta} optical emission-line widths (or, for one source, Br{alpha}), we find that there is no universal location of the Fe K{alpha} line-emitting region relative to the optical broad-line region (BLR). In general, a given source may have contributions to the Fe K{alpha} line flux from parsec-scale distances from the putative black hole, down to matter a factor {approx}2 closer to the black hole than the BLR. We confirm the presence of the X-ray Baldwin effect, an anti-correlation between the Fe K{alpha} line EW and X-ray continuum luminosity. The HEG data have enabled isolation of this effect to the narrow core of the Fe K{alpha} line.« less

Profits without People.

ERIC Educational Resources Information Center

Boutwell, Clinton E.

1997-01-01

America's corporate executives consider a huge world-class workforce superfluous. Corporate restructuring's bottom line was the massive shedding of workers, a reduction in future job opportunities, and a concomitant plunge in income, benefits, and living standards for millions. Experts predict that only 20% of well-trained college graduates will…

Estimating Large Numbers

ERIC Educational Resources Information Center

Landy, David; Silbert, Noah; Goldin, Aleah

2013-01-01

Despite their importance in public discourse, numbers in the range of 1 million to 1 trillion are notoriously difficult to understand. We examine magnitude estimation by adult Americans when placing large numbers on a number line and when qualitatively evaluating descriptions of imaginary geopolitical scenarios. Prior theoretical conceptions…

Near-infrared line and continuum emission from the blue dwarf galaxy II Zw 40

NASA Technical Reports Server (NTRS)

Joy, Marshall; Lester, Daniel F.

1988-01-01

A multicolor analysis of new near-infrared line and continuum measurements indicates that nebular recombination emission and photospheric radiation from young blue stars produce most of the near-infrared continuum emission in the central 6 arcsec of the dwarf galaxy II Zw 40. The derived nebular recombination level is in excellent agreement with independent observations of the radio free-free continuum. It is found that evolved stars, which dominate the near-infrared emission from normal galaxies, contribute no more than 25 percent of the total 2.2 micron flux in the central region of II Zw 40. It is concluded that the total mass of the evolved stellar population in the central 400 pc of the galaxy is less than about two hundred million solar. The total mass of recently formed stars is about two million solar, and the stellar mass ratio is exceptionally large. Thus, II Zw 40 is a quintessential starburst galaxy.

Public health burden of sudden cardiac death in the United States.

PubMed

Stecker, Eric C; Reinier, Kyndaron; Marijon, Eloi; Narayanan, Kumar; Teodorescu, Carmen; Uy-Evanado, Audrey; Gunson, Karen; Jui, Jonathan; Chugh, Sumeet S

2014-04-01

Sudden cardiac death (SCD) is a leading cause of death in the United States, but the relative public health burden is unknown. We estimated the burden of premature death from SCD and compared it with other diseases. Analyses were based on the following data sources (using most recent sources that provided appropriately stratified data): (1) leading causes of death among men and women from 2009 US death certificate reporting; (2) individual cancer mortality rates from 2008 death certificate reporting from the Centers for Disease Control and Prevention's National Program of Cancer Registries; (3) county, state, and national population data for 2009 from the US Census Bureau; and (4) SCD rates from the Oregon Sudden Unexpected Death Study (SUDS) population-based surveillance study of SCD between 2002 and 2004. Cases were identified from multiple sources in a prospectively designed surveillance program. Incidence, counts, and years of potential life lost for SCD and other major diseases were compared. The age-adjusted national incidence of SCD was 60 per 100 000 population (95% confidence interval, 54-66 per 100,000). The burden of premature death for men (2.04 million years of potential life lost; 95% uncertainty interval, 1.86-2.23 million) and women (1.29 million years of potential life lost; 95% uncertainty interval, 1.13-1.45 million) was greater for SCD than for all individual cancers and most other leading causes of death. The societal burden of SCD is high relative to other major causes of death. Accordingly, improved national surveillance with the goal of optimizing and monitoring SCD prevention and treatment should be a high priority.

Current perspectives in drug discovery against tuberculosis from natural products.

PubMed

Nguta, Joseph Mwanzia; Appiah-Opong, Regina; Nyarko, Alexander K; Yeboah-Manu, Dorothy; Addo, Phyllis G A

2015-09-01

Currently, one third of the world's population is latently infected with Mycobacterium tuberculosis (MTB), while 8.9-9.9 million new and relapse cases of tuberculosis (TB) are reported yearly. The renewed research interests in natural products in the hope of discovering new and novel antitubercular leads have been driven partly by the increased incidence of multidrug-resistant strains of MTB and the adverse effects associated with the first- and second-line antitubercular drugs. Natural products have been, and will continue to be a rich source of new drugs against many diseases. The depth and breadth of therapeutic agents that have their origins in the secondary metabolites produced by living organisms cannot be compared with any other source of therapeutic agents. Discovery of new chemical molecules against active and latent TB from natural products requires an interdisciplinary approach, which is a major challenge facing scientists in this field. In order to overcome this challenge, cutting edge techniques in mycobacteriology and innovative natural product chemistry tools need to be developed and used in tandem. The present review provides a cross-linkage to the most recent literature in both fields and their potential to impact the early phase of drug discovery against TB if seamlessly combined. Copyright © 2015 Asian African Society for Mycobacteriology. Published by Elsevier Ltd. All rights reserved.

RadioAstron Science Program Five Years after Launch: Main Science Results

NASA Astrophysics Data System (ADS)

Kardashev, N. S.; Alakoz, A. V.; Andrianov, A. S.; Artyukhov, M. I.; Baan, W.; Babyshkin, V. E.; Bartel, N.; Bayandina, O. S.; Val'tts, I. E.; Voitsik, P. A.; Vorobyov, A. Z.; Gwinn, C.; Gomez, J. L.; Giovannini, G.; Jauncey, D.; Johnson, M.; Imai, H.; Kovalev, Y. Y.; Kurtz, S. E.; Lisakov, M. M.; Lobanov, A. P.; Molodtsov, V. A.; Novikov, B. S.; Pogodin, A. V.; Popov, M. V.; Privesenzev, A. S.; Rudnitski, A. G.; Rudnitski, G. M.; Savolainen, T.; Smirnova, T. V.; Sobolev, A. M.; Soglasnov, V. A.; Sokolovsky, K. V.; Filippova, E. N.; Khartov, V. V.; Churikova, M. E.; Shirshakov, A. E.; Shishov, V. I.; Edwards, P.

2017-12-01

The RadioAstron ground-space interferometer provides the highest angular resolution achieved now in astronomy. The detection of interferometric fringes from quasars with this angular resolution on baselines of 100-200 thousand km suggests the brightness temperatures which exceed the Compton limit by two orders of magnitude. Polarimetric measurements on ground-space baselines have revealed fine structure testifying to recollimation shocks on scales of 100-250 μas and a helical magnetic field near the base of radio emission in BL Lacertae. Substructure within a the scattering disk of pulsar emission on interferometer baselines (from 60000 to 250000 km) was discovered. This substructure is produced by action of the interstellar interferometer with an effective baseline of about 1 AU and the effective angular resolution of better than 1 μas. Diameters of scattering disks were measured for several pulsars, and distances to diffusing screens were evaluated. The ground-space observations of sources of the maser radiation in lines of water and hydroxyl have shown that the maser sources in star-forming regions remain unresolved on baselines, which considerably exceed the Earth diameter. These very compact and bright features with angular sizes of about 20-60 μas correspond to linear sizes of about 5-10 million km (several solar diameters).

Blind Spectroscopic Galaxy Surveys Using an Ultra-Wide-Band Imaging Spectrograph on AtLAST and LST

NASA Astrophysics Data System (ADS)

Kohno, Kotaro

2018-01-01

A novel approach to elucidation of cosmic star formation history is a blind search for CO and [CII] emissions using a ultra-wide-band imaging spectrograph on the future large submm telescopes like AtLAST and LST. In particular, searching for [CII] emitters in the appropriate frequency range allows us to sample those sources very efficiently for a redshift range of 3.5 to 9 (190 to 420 GHz), reaching the star-formation in the EoR. Further, spectroscopic analysis of CO in the lower frequency bands will constrain the evolution of CO luminosity functions across cosmic time. We conducted a feasibility study of ``CO/[CII] tomography'' based on a mock galaxy catalog containing 1.4 million objects drawn from the S(3) -SAX (Obreschkow et al. 2009). We find that a blind spectroscopic survey using a 50-m telescope equipped with a 100-pixel imaging spectrograph, which covers 70-370 GHz simultaneously, will be promising indeed. A survey of 2 deg(2) in 1,000 hr (on-source) will uncover > 10^5 line-emitting galaxies in total, including 10^3 [CII] emitters in the EoR (Tamura et al., in prep.). Wider surveys (10 deg^2 or wider) will also be discussed for RSD science cases.

40 CFR 471.13 - New source performance standards (NSPS).

Code of Federal Regulations, 2011 CFR

2011-07-01

... GUIDELINES AND STANDARDS NONFERROUS METALS FORMING AND METAL POWDERS POINT SOURCE CATEGORY Lead-Tin-Bismuth...-tin-bismuth forming operations' process wastewater shall not exceed the following values: (a) Rolling... monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with emulsions...

40 CFR 471.13 - New source performance standards (NSPS).

Code of Federal Regulations, 2010 CFR

2010-07-01

... GUIDELINES AND STANDARDS NONFERROUS METALS FORMING AND METAL POWDERS POINT SOURCE CATEGORY Lead-Tin-Bismuth...-tin-bismuth forming operations' process wastewater shall not exceed the following values: (a) Rolling... monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with emulsions...

40 CFR 421.324 - Standards of performance for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Secondary Uranium... Uranium Subcategory Pollutant or pollutant property Maximum for any 1 day Maximum for monthly average mg/kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 27.14 11.00...

40 CFR 421.324 - Standards of performance for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Secondary Uranium... Uranium Subcategory Pollutant or pollutant property Maximum for any 1 day Maximum for monthly average mg/kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 27.14 11.00...

40 CFR 421.324 - Standards of performance for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) EFFLUENT GUIDELINES AND STANDARDS NONFERROUS METALS MANUFACTURING POINT SOURCE CATEGORY Secondary Uranium... Uranium Subcategory Pollutant or pollutant property Maximum for any 1 day Maximum for monthly average mg/kg (pounds per million pounds) of uranium processed in the refinery Chromium (total) 27.14 11.00...

Heavy Metal.

ERIC Educational Resources Information Center

Black, Susan

2001-01-01

The Centers for Disease Control and Prevention (CDC) estimate that more than 1 million children ages 5 and under are afflicted with unsafe amounts of lead. Schools can be a source of lead poisoning. Other sources include playgrounds near freeways, playground equipment, contaminated soil, and technology rooms with lead-bearing supplies. Sidebars…

Sources of revenue for nonprofit mental health and addictions organizations in Canada.

PubMed

Escober-Doran, Carissa; Jacobs, Philip; Dewa, Carolyn

2010-10-01

In Canada charitable or nonprofit organizations provide government-contracted mental health and addictions services, and they augment government funding by raising charitable revenues. This study estimated by source the revenues of nonprofit mental health and addictions organizations in Canada. A list of nonprofit, service-providing organizations in Canada was developed, financial returns to the Canada Revenue Agency (CRA) in 2007 were obtained, and data were analyzed in aggregate. Information was obtained from 369 Canadian organizations, which had $915.4 million (Canadian dollars [CAD]) in total revenues: 85% were from the government, 4% were from charitable giving, and 11% were from other sources. The ratio of charitable giving to government funding of mental health care was about .55% ($35 million to $6.3 billion CAD). This charitable giving level cannot compensate for the relatively low levels of total government mental health spending identified in government reports.

40 CFR 421.305 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pounds) of TiCl4 produced Chromium (total) 0.346 0.140 Lead 0.262 0.122 Nickel 0.515 0.346 Titanium 0.496.../kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.385 0.156 Lead 0.291 0.135 Nickel... monthly average mg/kg (pounds per million pounds) of TiCl4 handled Chromium (total) 0.069 0.028 Lead 0.052...

40 CFR 421.305 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... pounds) of TiCl4 produced Chromium (total) 0.346 0.140 Lead 0.262 0.122 Nickel 0.515 0.346 Titanium 0.496.../kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.385 0.156 Lead 0.291 0.135 Nickel... monthly average mg/kg (pounds per million pounds) of TiCl4 handled Chromium (total) 0.069 0.028 Lead 0.052...

40 CFR 421.305 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... pounds) of TiCl4 produced Chromium (total) 0.346 0.140 Lead 0.262 0.122 Nickel 0.515 0.346 Titanium 0.496.../kg (pounds per million pounds) of TiCl4 produced Chromium (total) 0.385 0.156 Lead 0.291 0.135 Nickel... monthly average mg/kg (pounds per million pounds) of TiCl4 handled Chromium (total) 0.069 0.028 Lead 0.052...

Evaluation of the incremental cost to the National Health Service of prescribing analogue insulin

PubMed Central

Holden, Sarah E; Poole, Chris D; Morgan, Christopher Ll

2011-01-01

Introduction Insulin analogues have become increasingly popular despite their greater cost compared with human insulin. The aim of this study was to calculate the incremental cost to the National Health Service (NHS) of prescribing analogue insulin preparations instead of their human insulin alternatives. Methods Open-source data from the four UK prescription pricing agencies from 2000 to 2009 were analysed. Cost was adjusted for inflation and reported in UK pounds at 2010 prices. Results Over the 10-year period, the NHS spent a total of £2732 million on insulin. The total annual cost increased from £156 million to £359 million, an increase of 130%. The annual cost of analogue insulin increased from £18.2 million (12% of total insulin cost) to £305 million (85% of total insulin cost), whereas the cost of human insulin decreased from £131 million (84% of total insulin cost) to £51 million (14% of total insulin cost). If it is assumed that all patients using insulin analogues could have received human insulin instead, the overall incremental cost of analogue insulin was £625 million. Conclusion Given the high marginal cost of analogue insulin, adherence to prescribing guidelines recommending the preferential use of human insulin would have resulted in considerable financial savings over the period. PMID:22021891

Estimated water use in Puerto Rico, 2000

USGS Publications Warehouse

Molina-Rivera, Wanda L.

2005-01-01

Water-use data were compiled for the 78 municipios of the Commonwealth of Puerto Rico for 2000. Five offstream categories were considered: public-supply water withdrawals, domestic self-supplied water use, industrial self-supplied withdrawals, crop irrigation water use, and thermoelectric power fresh water use. Two additional categories also were considered: power generation instream use and public wastewater treatment return-flows. Fresh water withdrawals for offstream use from surface- and ground-water sources in Puerto Rico were estimated at 617 million gallons per day. The largest amount of fresh water withdrawn was by public-supply water facilities and was estimated at 540 million gallons per day. Fresh surface- and ground-water withdrawals by domestic self-supplied users was estimated at 2 million gallons per day and the industrial self-supplied withdrawals were estimated at 9.5 million gallons per day. Withdrawals for crop irrigation purposes were estimated at 64 million gallons per day, or approximately 10 percent of all offstream fresh water withdrawals. Saline instream surface-water withdrawals for cooling purposes by thermoelectric power facilities was estimated at 2,191 million gallons per day, and instream fresh water withdrawals by hydroelectric facilities at 171 million gallons per day. Total discharge from public wastewater treatment facilities was estimated at 211 million gallons per day.

Inpatient charges and mental illness: Findings from the Nationwide Inpatient Sample 1999-2007.

PubMed

Banta, Jim E; Belk, Ivorie; Newton, Kedon; Sherzai, Abdullah

2010-01-01

Inpatient costs related to mental illness are substantial, though declining as a percentage of overall mental health treatment costs. The public sector has become increasingly involved in funding and providing mental health services. Nationwide Inpatient Sample data for the years 1999-2007 were used to: 1) examine Medicare, Medicaid, and private insurance charges related to mental illness hospitalizations, including trends over time; and 2) examine trends in mental comorbidity with physical illness and its effect on charges. There were an estimated 12.4 million mental illness discharges during the 9-year period, with Medicare being the primary payer for 4.3 million discharges, Medicaid for 3.3 million, private insurance for 3.2 million, and 1.6 million for all other payers. Mean inflation-adjusted charges per hospitalization were US$17,528, US$15,651, US$10,539, and US$11,663, respectively. Charges to public sources increased for schizophrenia and dementia-related discharges, with little private/public change noted for mood disorders. Comorbid mood disorders increased dramatically from 1.5 million discharges in 1999 to 3.4 million discharges in 2007. Comorbid illness was noted in 14.0% of the 342 million inpatient discharges during the study period and was associated with increased charges for some medical conditions and decreased charges for other medical conditions.

Do Atoms Really "Emit" Absorption Lines?

ERIC Educational Resources Information Center

Brecher, Kenneth

1991-01-01

Presents three absorption line sources that enhance student understanding of the phenomena associated with the interaction of light with matter and help dispel the misconception that atoms "emit" absorption lines. Sources include neodymium, food coloring and other common household liquids, and fluorescent materials. (MDH)

Neon and [CII] 158 μm Emission Line Profiles in Dusty Starbursts and Active Galactic Nuclei

NASA Astrophysics Data System (ADS)

Samsonyan, A.; Weedman, D.; Lebouteiller, V.; Barry, D.; Sargsyan, L.

2017-07-01

Identifying and understanding the initial formation of massive galaxies and quasars in the early universe is a fundamental goal of observational cosmology. A rapidly developing capability for tracing luminosity sources to high redshifts is the observation of the [CII] 158 μm emission line at redshifts z > 4 using ground based submillimeter interferometers, with detections now having been made to z = 7. This has long been known as the strongest far-infrared line in most sources, often carrying about 1% of the total source luminosity, and is thought to be associated with star formation because it should arise within the photodissociation region (PDR) surrounding starbursts. The sample of 382 extragalactic sources has been analysed that have mid-infrared,high resolution spectroscopy with the Spitzer Infrared Spectrograph (IRS) and also spectroscopy of the [CII] 158 μm line with the Herschel Photodetector Array Camera and Spectrometer (PACS). The emission line profiles of [NeII] 12.81μm , [NeIII] 15.55 μm , and [CII] 158 μm are studied, and intrinsic line widths are determined. All line profiles together with overlays comparing positions of PACS and IRS observations are made available in the Cornell Atlas of Spitzer IRS Sources (CASSIS). Sources are classified from AGN to starburst based on equivalent widths of the 6.2 μm polycyclic aromatic hydrocarbon feature. It is found that intrinsic line widths do not change among classification for [CII], with median widths of 207 km s-1 for AGN, 248 km s-1 for composites, and 233 km s-1 for starbursts. The [NeII] line widths also do not change with classification, but [NeIII] lines are progressively broader from starburst to AGN. A small number of objects with unusually broad lines or unusual redshift differences in any feature are identified.

Assessing the economic and environmental feasibility of utility scaled PV electricity production in the state of Georgia.

PubMed

Taylor, Ruthie; Critttenden, John

2012-01-01

Photovoltaic (PV) technology, an increasingly popular source for renewable energy, is being deployed in places with solar insolation that is comparable to that in state of Georgia. This study assesses the feasibility and environmental impact of utility scale photovoltaic (PV) electricity production in Georgia by assessing the economic costs, avoided costs, health benefits, and environmental benefits. The cost of PV used in this study is 3.52 $/kW. The RETScreen model was employed to analyze the impact of incentives on the economic viability of the plants that produce 93 GWh, 371 GWh, and 1,484 GWh, respectively. 57% of the capital cost is required in the form of incentives or subsidies to make the projects economically feasible. The high estimated cost of cleaning the equivalent amount of emissions from a coal-fired power plant is $14.5 million, $58 million, and $232 million for a 50 MW, 200 MW, and 800 MW plant, respectively Avoided costs in health damages are estimated to be $28 million, $112 million, and $449 million and the numbers of jobs to be created are 2,500, 10,000, and 40,000 for 50 MW, 200 MW, and 800 MW plants, respectively. And, the cumulative value of renewable energy credits from a 50 MW, 200 MW, and a 800 MW plant are $59 million, $237 million, and $789 million, respectively.

Quality of Malaria Case Management in Malawi: Results from a Nationally Representative Health Facility Survey

PubMed Central

Steinhardt, Laura C.; Chinkhumba, Jobiba; Wolkon, Adam; Luka, Madalitso; Luhanga, Misheck; Sande, John; Oyugi, Jessica; Ali, Doreen; Mathanga, Don; Skarbinski, Jacek

2014-01-01

Background Malaria is endemic throughout Malawi, but little is known about quality of malaria case management at publicly-funded health facilities, which are the major source of care for febrile patients. Methods In April–May 2011, we conducted a nationwide, geographically-stratified health facility survey to assess the quality of outpatient malaria diagnosis and treatment. We enrolled patients presenting for care and conducted exit interviews and re-examinations, including reference blood smears. Moreover, we assessed health worker readiness (e.g., training, supervision) and health facility capacity (e.g. availability of diagnostics and antimalarials) to provide malaria case management. All analyses accounted for clustering and unequal selection probabilities. We also used survey weights to produce estimates of national caseloads. Results At the 107 facilities surveyed, most of the 136 health workers interviewed (83%) had received training on malaria case management. However, only 24% of facilities had functional microscopy, 15% lacked a thermometer, and 19% did not have the first-line artemisinin-based combination therapy (ACT), artemether-lumefantrine, in stock. Of 2,019 participating patients, 34% had clinical malaria (measured fever or self-reported history of fever plus a positive reference blood smear). Only 67% (95% confidence interval (CI): 59%, 76%) of patients with malaria were correctly prescribed an ACT, primarily due to missed malaria diagnosis. Among patients without clinical malaria, 31% (95% CI: 24%, 39%) were prescribed an ACT. By our estimates, 1.5 million of the 4.4 million malaria patients seen in public facilities annually did not receive correct treatment, and 2.7 million patients without clinical malaria were inappropriately given an ACT. Conclusions Malawi has a high burden of uncomplicated malaria but nearly one-third of all patients receive incorrect malaria treatment, including under- and over-treatment. To improve malaria case management, facilities must at minimum have basic case management tools, and health worker performance in diagnosing malaria must be improved. PMID:24586497

Estimating antimalarial drugs consumption in Africa before the switch to artemisinin-based combination therapies (ACTs).

PubMed

Kindermans, Jean-Marie; Vandenbergh, Daniel; Vreeke, Ed; Olliaro, Piero; D'Altilia, Jean-Pierre

2007-07-10

Having reliable forecasts is critical now for producers, malaria-endemic countries and agencies in order to adapt production and procurement of the artemisinin-based combination treatments (ACTs), the new first-line treatments of malaria. There is no ideal method to quantify drug requirements for malaria. Morbidity data give uncertain estimations. This study uses drug consumption to provide elements to help estimate quantities and financial requirements of ACTs. The consumption of chloroquine, sulphadoxine/pyrimethamine and quinine both through the private and public sector was assessed in five sub-Saharan Africa countries with different epidemiological patterns (Senegal, Rwanda, Tanzania, Malawi, Zimbabwe). From these data the number of adult treatments per capita was calculated and the volumes and financial implications derived for the whole of Africa. Identifying and obtaining data from the private sector was difficult. The quality of information on drug supply and distribution in countries must be improved. The number of adult treatments per capita and per year in the five countries ranged from 0.18 to 0.50. Current adult treatment prices for ACTs range US$ 1-1.8. Taking the upper range for both volumes and costs, the highest number of adult treatments consumed for Africa was estimated at 314.5 million, corresponding to an overall maximum annual need for financing ACT procurement of US$ 566.1 million. In reality, both the number of cases treated and the cost of treatment are likely to be lower (projections for the lowest consumption estimate with the least expensive ACT would require US $ 113 million per annum). There were substantial variations in the market share between public and private sources among these countries (the public sector share ranging from 98% in Rwanda to 33% in Tanzania). Additional studies are required to build a more robust methodology, and to assess current consumptions more accurately in order to better quantify volumes and finances for production and procurement of ACTs.

Quality of malaria case management in Malawi: results from a nationally representative health facility survey.

PubMed

Steinhardt, Laura C; Chinkhumba, Jobiba; Wolkon, Adam; Luka, Madalitso; Luhanga, Misheck; Sande, John; Oyugi, Jessica; Ali, Doreen; Mathanga, Don; Skarbinski, Jacek

2014-01-01

Malaria is endemic throughout Malawi, but little is known about quality of malaria case management at publicly-funded health facilities, which are the major source of care for febrile patients. In April-May 2011, we conducted a nationwide, geographically-stratified health facility survey to assess the quality of outpatient malaria diagnosis and treatment. We enrolled patients presenting for care and conducted exit interviews and re-examinations, including reference blood smears. Moreover, we assessed health worker readiness (e.g., training, supervision) and health facility capacity (e.g. availability of diagnostics and antimalarials) to provide malaria case management. All analyses accounted for clustering and unequal selection probabilities. We also used survey weights to produce estimates of national caseloads. At the 107 facilities surveyed, most of the 136 health workers interviewed (83%) had received training on malaria case management. However, only 24% of facilities had functional microscopy, 15% lacked a thermometer, and 19% did not have the first-line artemisinin-based combination therapy (ACT), artemether-lumefantrine, in stock. Of 2,019 participating patients, 34% had clinical malaria (measured fever or self-reported history of fever plus a positive reference blood smear). Only 67% (95% confidence interval (CI): 59%, 76%) of patients with malaria were correctly prescribed an ACT, primarily due to missed malaria diagnosis. Among patients without clinical malaria, 31% (95% CI: 24%, 39%) were prescribed an ACT. By our estimates, 1.5 million of the 4.4 million malaria patients seen in public facilities annually did not receive correct treatment, and 2.7 million patients without clinical malaria were inappropriately given an ACT. Malawi has a high burden of uncomplicated malaria but nearly one-third of all patients receive incorrect malaria treatment, including under- and over-treatment. To improve malaria case management, facilities must at minimum have basic case management tools, and health worker performance in diagnosing malaria must be improved.

Diffusion from a line source

NASA Technical Reports Server (NTRS)

Burns, R. E.

1973-01-01

The problem with predicting pollutant diffusion from a line source of arbitrary geometry is treated. The concentration at the line source may be arbitrarily varied with time. Special attention is given to the meteorological inputs which act as boundary conditions for the problem, and a mixing layer of arbitrary depth is assumed. Numerical application of the derived theory indicates the combinations of meteorological parameters that may be expected to result in high pollution concentrations.

Multi-channel Analysis of Passive Surface Waves (MAPS)

NASA Astrophysics Data System (ADS)

Xia, J.; Cheng, F. Mr; Xu, Z.; Wang, L.; Shen, C.; Liu, R.; Pan, Y.; Mi, B.; Hu, Y.

2017-12-01

Urbanization is an inevitable trend in modernization of human society. In the end of 2013 the Chinese Central Government launched a national urbanization plan—"Three 100 Million People", which aggressively and steadily pushes forward urbanization. Based on the plan, by 2020, approximately 100 million people from rural areas will permanently settle in towns, dwelling conditions of about 100 million people in towns and villages will be improved, and about 100 million people in the central and western China will permanently settle in towns. China's urbanization process will run at the highest speed in the urbanization history of China. Environmentally friendly, non-destructive and non-invasive geophysical assessment method has played an important role in the urbanization process in China. Because human noise and electromagnetic field due to industrial life, geophysical methods already used in urban environments (gravity, magnetics, electricity, seismic) face great challenges. But humanity activity provides an effective source of passive seismic methods. Claerbout pointed out that wavefileds that are received at one point with excitation at the other point can be reconstructed by calculating the cross-correlation of noise records at two surface points. Based on this idea (cross-correlation of two noise records) and the virtual source method, we proposed Multi-channel Analysis of Passive Surface Waves (MAPS). MAPS mainly uses traffic noise recorded with a linear receiver array. Because Multi-channel Analysis of Surface Waves can produces a shear (S) wave velocity model with high resolution in shallow part of the model, MPAS combines acquisition and processing of active source and passive source data in a same flow, which does not require to distinguish them. MAPS is also of ability of real-time quality control of noise recording that is important for near-surface applications in urban environment. The numerical and real-world examples demonstrated that MAPS can be used for accurate and fast imaging of high-frequency surface wave energy, and some examples also show that high quality imaging similar to those with active sources can be generated only by the use of a few minutes of noise. The use of cultural noise in town, MAPS can image S-wave velocity structure from the ground surface to hundreds of meters depth.

Geology and oil and gas assessment of the Todilto Total Petroleum System, San Juan Basin Province, New Mexico and Colorado: Chapter 3 in Total petroleum systems and geologic assessment of undiscovered oil and gas resources in the San Juan Basin Province, exclusive of Paleozoic rocks, New Mexico and Colorado

USGS Publications Warehouse

Ridgley, J.L.; Hatch, J.R.

2013-01-01

Organic-rich, shaly limestone beds, which contain hydrocarbon source beds in the lower part of the Jurassic Todilto Limestone Member of the Wanakah Formation, and sandstone reservoirs in the overlying Jurassic Entrada Sandstone, compose the Todilto Total Petroleum System (TPS). Source rock facies of the Todilto Limestone were deposited in a combined marine-lacustrine depositional setting. Sandstone reservoirs in the Entrada Sandstone were deposited in eolian depositional environments. Oil in Todilto source beds was generated beginning in the middle Paleocene, about 63 million years ago, and maximum generation of oil occurred in the middle Eocene. In the northern part of the San Juan Basin, possible gas and condensate were generated in Todilto Limestone Member source beds until the middle Miocene. The migration distance of oil from the Todilto source beds into the underlying Entrada Sandstone reservoirs was short, probably within the dimensions of a single dune crest. Traps in the Entrada are mainly stratigraphic and diagenetic. Regional tilt of the strata to the northeast has influenced structural trapping of oil, but also allowed for later introduction of water. Subsequent hydrodynamic forces have influenced the repositioning of the oil in some reservoirs and flushing in others. Seals are mostly the anhydrite and limestone facies of the Todilto, which thin to as little as 10 ft over the crests of the dunes. The TPS contains only one assessment unit, the Entrada Sandstone Conventional Oil Assessment Unit (AU) (50220401). Only four of the eight oil fields producing from the Entrada met the 0.5 million barrels of oil minimum size used for this assessment. The AU was estimated at the mean to have potential additions to reserves of 2.32 million barrels of oil (MMBO), 5.56 billion cubic feet of natural gas (BCFG), and 0.22 million barrels of natural gas liquids (MMBNGL).

40 CFR 471.14 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2012 CFR

2012-07-01

... CATEGORY Lead-Tin-Bismuth Forming Subcategory § 471.14 Pretreatment standards for existing sources (PSES... in lead-tin-bismuth forming process wastewater introduced into a POTW shall not exceed the following... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.14 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2011 CFR

2011-07-01

...-Tin-Bismuth Forming Subcategory § 471.14 Pretreatment standards for existing sources (PSES). Except as...-tin-bismuth forming process wastewater introduced into a POTW shall not exceed the following values... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.14 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2014 CFR

2014-07-01

... CATEGORY Lead-Tin-Bismuth Forming Subcategory § 471.14 Pretreatment standards for existing sources (PSES... in lead-tin-bismuth forming process wastewater introduced into a POTW shall not exceed the following... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.14 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2010 CFR

2010-07-01

...-Tin-Bismuth Forming Subcategory § 471.14 Pretreatment standards for existing sources (PSES). Except as...-tin-bismuth forming process wastewater introduced into a POTW shall not exceed the following values... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

40 CFR 471.14 - Pretreatment standards for existing sources (PSES).

Code of Federal Regulations, 2013 CFR

2013-07-01

... CATEGORY Lead-Tin-Bismuth Forming Subcategory § 471.14 Pretreatment standards for existing sources (PSES... in lead-tin-bismuth forming process wastewater introduced into a POTW shall not exceed the following... Maximum for monthly average mg/off-kg (pounds per million off-pounds) of lead-tin-bismuth rolled with...

Starch and protein chemistry and functional properties

USDA-ARS?s Scientific Manuscript database

Starch and protein are the major constituents of all cereal grains and are an important source of nutrition for humans and animals. Worldwide, sorghum and the millets are basic food staples for millions of people and are important sources of animal feed, and in some cases fuel. The chemical properti...

40 CFR 467.36 - Pretreatment standards for new sources.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... 467.36 Section 467.36 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Extrusion Subcategory § 467.36 Pretreatment... day Maximum for monthly average mg/off-kg (lb/million off-lbs) of extruded Chromium 0.13 0.05 Cyanide...

First Detections of the [NII] 122 Micrometer Line at High Redshift: Demonstrating the Utility of the Line for Studying Galaxies in the Early Universe

NASA Technical Reports Server (NTRS)

Ferkinhoff, Carl; Brisbin, Drew; Nikola, Thomas; Parshley, Stephen C.; Stacey, Gordon J.; Phillips, Thomas G.; Falgarone, Edith; Benford, Dominic J.; Staguhn, Johannes G.; Tucker, Carol E.

2011-01-01

We report the first detections of the [NIl] 122 {\\mu} m line from a high redshift galaxy. The line was strongly (> 6{\\sigma}) detected from SMMJ02399-0136, and HI413+ 117 (the Cloverleaf QSO) using the Redshift(z) and Early Universe Spectrometer (ZEUS) on the CSO. The lines from both sources are quite bright with line-to-FIR continuum luminosity ratios that are approx.7.0x10(exp -4) (Cloverleaf) and 2.1x10(exp -3) (SMMJ02399). With ratios 2-10 times larger than the average value for nearby galaxies, neither source exhibits the line-to-continuum deficits seen in nearby sources. The line strengths also indicate large ionized gas fractions, approx.8 to 17% of the molecular gas mass. The [OIII]/[NII] line ratio is very sensitive to the effective temperature of ionizing stars and the ionization parameter for emission arising in the narrow-line region (NLR) of an AGN. Using our previous detection of the [01II] 88 {\\mu}m line, the [OIII]/ [NIl] line ratio for SMMJ02399-0136 indicates the dominant source of the line emission is either stellar HII regions ionized by 09.5 stars, or the NLR of the AGN with ionization parameter 10g(U) = -3.3 to -4.0. A composite system, where 30 to 50% of the FIR lines arise in the NLR also matches the data. The Cloverleaf is best modeled by a superposition of approx.200 M82like starbursts accounting for all of the FIR emission and 43% of the [NIl] line. The remainder may come from the NLR. This work demonstrates the utility of the [NIl] and [OIII] lines in constraining properties of the ionized medium.

World Health Organization Estimates of the Global and Regional Disease Burden of 22 Foodborne Bacterial, Protozoal, and Viral Diseases, 2010: A Data Synthesis.

PubMed

Kirk, Martyn D; Pires, Sara M; Black, Robert E; Caipo, Marisa; Crump, John A; Devleesschauwer, Brecht; Döpfer, Dörte; Fazil, Aamir; Fischer-Walker, Christa L; Hald, Tine; Hall, Aron J; Keddy, Karen H; Lake, Robin J; Lanata, Claudio F; Torgerson, Paul R; Havelaar, Arie H; Angulo, Frederick J

2015-12-01

Foodborne diseases are important worldwide, resulting in considerable morbidity and mortality. To our knowledge, we present the first global and regional estimates of the disease burden of the most important foodborne bacterial, protozoal, and viral diseases. We synthesized data on the number of foodborne illnesses, sequelae, deaths, and Disability Adjusted Life Years (DALYs), for all diseases with sufficient data to support global and regional estimates, by age and region. The data sources included varied by pathogen and included systematic reviews, cohort studies, surveillance studies and other burden of disease assessments. We sought relevant data circa 2010, and included sources from 1990-2012. The number of studies per pathogen ranged from as few as 5 studies for bacterial intoxications through to 494 studies for diarrheal pathogens. To estimate mortality for Mycobacterium bovis infections and morbidity and mortality for invasive non-typhoidal Salmonella enterica infections, we excluded cases attributed to HIV infection. We excluded stillbirths in our estimates. We estimate that the 22 diseases included in our study resulted in two billion (95% uncertainty interval [UI] 1.5-2.9 billion) cases, over one million (95% UI 0.89-1.4 million) deaths, and 78.7 million (95% UI 65.0-97.7 million) DALYs in 2010. To estimate the burden due to contaminated food, we then applied proportions of infections that were estimated to be foodborne from a global expert elicitation. Waterborne transmission of disease was not included. We estimate that 29% (95% UI 23-36%) of cases caused by diseases in our study, or 582 million (95% UI 401-922 million), were transmitted by contaminated food, resulting in 25.2 million (95% UI 17.5-37.0 million) DALYs. Norovirus was the leading cause of foodborne illness causing 125 million (95% UI 70-251 million) cases, while Campylobacter spp. caused 96 million (95% UI 52-177 million) foodborne illnesses. Of all foodborne diseases, diarrheal and invasive infections due to non-typhoidal S. enterica infections resulted in the highest burden, causing 4.07 million (95% UI 2.49-6.27 million) DALYs. Regionally, DALYs per 100,000 population were highest in the African region followed by the South East Asian region. Considerable burden of foodborne disease is borne by children less than five years of age. Major limitations of our study include data gaps, particularly in middle- and high-mortality countries, and uncertainty around the proportion of diseases that were foodborne. Foodborne diseases result in a large disease burden, particularly in children. Although it is known that diarrheal diseases are a major burden in children, we have demonstrated for the first time the importance of contaminated food as a cause. There is a need to focus food safety interventions on preventing foodborne diseases, particularly in low- and middle-income settings.

World Health Organization Estimates of the Global and Regional Disease Burden of 22 Foodborne Bacterial, Protozoal, and Viral Diseases, 2010: A Data Synthesis

PubMed Central

Kirk, Martyn D.; Pires, Sara M.; Black, Robert E.; Caipo, Marisa; Crump, John A.; Devleesschauwer, Brecht; Döpfer, Dörte; Fazil, Aamir; Fischer-Walker, Christa L.; Hald, Tine; Hall, Aron J.; Keddy, Karen H.; Lake, Robin J.; Lanata, Claudio F.; Torgerson, Paul R.; Havelaar, Arie H.; Angulo, Frederick J.

2015-01-01

Background Foodborne diseases are important worldwide, resulting in considerable morbidity and mortality. To our knowledge, we present the first global and regional estimates of the disease burden of the most important foodborne bacterial, protozoal, and viral diseases. Methods and Findings We synthesized data on the number of foodborne illnesses, sequelae, deaths, and Disability Adjusted Life Years (DALYs), for all diseases with sufficient data to support global and regional estimates, by age and region. The data sources included varied by pathogen and included systematic reviews, cohort studies, surveillance studies and other burden of disease assessments. We sought relevant data circa 2010, and included sources from 1990–2012. The number of studies per pathogen ranged from as few as 5 studies for bacterial intoxications through to 494 studies for diarrheal pathogens. To estimate mortality for Mycobacterium bovis infections and morbidity and mortality for invasive non-typhoidal Salmonella enterica infections, we excluded cases attributed to HIV infection. We excluded stillbirths in our estimates. We estimate that the 22 diseases included in our study resulted in two billion (95% uncertainty interval [UI] 1.5–2.9 billion) cases, over one million (95% UI 0.89–1.4 million) deaths, and 78.7 million (95% UI 65.0–97.7 million) DALYs in 2010. To estimate the burden due to contaminated food, we then applied proportions of infections that were estimated to be foodborne from a global expert elicitation. Waterborne transmission of disease was not included. We estimate that 29% (95% UI 23–36%) of cases caused by diseases in our study, or 582 million (95% UI 401–922 million), were transmitted by contaminated food, resulting in 25.2 million (95% UI 17.5–37.0 million) DALYs. Norovirus was the leading cause of foodborne illness causing 125 million (95% UI 70–251 million) cases, while Campylobacter spp. caused 96 million (95% UI 52–177 million) foodborne illnesses. Of all foodborne diseases, diarrheal and invasive infections due to non-typhoidal S. enterica infections resulted in the highest burden, causing 4.07 million (95% UI 2.49–6.27 million) DALYs. Regionally, DALYs per 100,000 population were highest in the African region followed by the South East Asian region. Considerable burden of foodborne disease is borne by children less than five years of age. Major limitations of our study include data gaps, particularly in middle- and high-mortality countries, and uncertainty around the proportion of diseases that were foodborne. Conclusions Foodborne diseases result in a large disease burden, particularly in children. Although it is known that diarrheal diseases are a major burden in children, we have demonstrated for the first time the importance of contaminated food as a cause. There is a need to focus food safety interventions on preventing foodborne diseases, particularly in low- and middle-income settings. PMID:26633831

Cornstalk as a source of fiber and energy

Treesearch

Aziz Ahmed; J. Y. Zhu

2006-01-01

Wood is the major source of fiber supply. Non-wood fibers are mainly used in papermaking where there is a lack of forest resource such as in China and India. Cornstalk, among the agricultural residues and other non-wood fiber, is the most promising source of fiber. However, The usage of cornstalks is very limited in pulp and paper industry, although nearly 284 million...

Sodium D-line emission from Io - Comparison of observed and theoretical line profiles

NASA Technical Reports Server (NTRS)

Carlson, R. W.; Matson, D. L.; Johnson, T. V.; Bergstralh, J. T.

1978-01-01

High-resolution spectra of the D-line profiles have been obtained for Io's sodium emission cloud. These lines, which are produced through resonance scattering of sunlight, are broad and asymmetric and can be used to infer source and dynamical properties of the sodium cloud. In this paper we compare line profile data with theoretical line shapes computed for several assumed initial velocity distributions corresponding to various source mechanisms. We also examine the consequences of source distributions which are nonuniform over the surface of Io. It is found that the experimental data are compatible with escape of sodium atoms from the leading hemisphere of Io and with velocity distributions characteristic of sputtering processes. Thermal escape and simple models of plasma sweeping are found to be incompatible with the observations.

The Southern Argentina Agile Meteor Radar Orbital System (SAAMER-OS): An Initial Sporadic Meteoroid Orbital Survey in the Southern Sky

NASA Technical Reports Server (NTRS)

Janches, D.; Close, S.; Hormaechea, J. L.; Swarnalingam, N.; Murphy, A.; O'Connor, D.; Vandepeer, B.; Fuller, B.; Fritts, D. C.; Brunini, C.

2015-01-01

We present an initial survey in the southern sky of the sporadic meteoroid orbital environment obtained with the Southern Argentina Agile MEteor Radar (SAAMER) Orbital System (OS), in which over three-quarters of a million orbits of dust particles were determined from 2012 January through 2015 April. SAAMER-OS is located at the southernmost tip of Argentina and is currently the only operational radar with orbit determination capability providing continuous observations of the southern hemisphere. Distributions of the observed meteoroid speed, radiant, and heliocentric orbital parameters are presented, as well as those corrected by the observational biases associated with the SAAMER-OS operating parameters. The results are compared with those reported by three previous surveys performed with the Harvard Radio Meteor Project, the Advanced Meteor Orbit Radar, and the Canadian Meteor Orbit Radar, and they are in agreement with these previous studies. Weighted distributions for meteoroids above the thresholds for meteor trail electron line density, meteoroid mass, and meteoroid kinetic energy are also considered. Finally, the minimum line density and kinetic energy weighting factors are found to be very suitable for meteoroid applications. The outcomes of this work show that, given SAAMERs location, the system is ideal for providing crucial data to continuously study the South Toroidal and South Apex sporadic meteoroid apparent sources.

Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity.

PubMed

Kruger, Matthew; Boney, Robert; Ordoobadi, Alexander J; Sommers, Thomas F; Trapani, Josef G; Coffin, Allison B

2016-01-01

Moderate to severe hearing loss affects 360 million people worldwide and most often results from damage to sensory hair cells. Hair cell damage can result from aging, genetic mutations, excess noise exposure, and certain medications including aminoglycoside antibiotics. Aminoglycosides are effective at treating infections associated with cystic fibrosis and other life-threatening conditions such as sepsis, but cause hearing loss in 20-30% of patients. It is therefore imperative to develop new therapies to combat hearing loss and allow safe use of these potent antibiotics. We approach this drug discovery question using the larval zebrafish lateral line because zebrafish hair cells are structurally and functionally similar to mammalian inner ear hair cells and respond similarly to toxins. We screened a library of 502 natural compounds in order to identify novel hair cell protectants. Our screen identified four bisbenzylisoquinoline derivatives: berbamine, E6 berbamine, hernandezine, and isotetrandrine, each of which robustly protected hair cells from aminoglycoside-induced damage. Using fluorescence microscopy and electrophysiology, we demonstrated that the natural compounds confer protection by reducing antibiotic uptake into hair cells and showed that hair cells remain functional during and after incubation in E6 berbamine. We also determined that these natural compounds do not reduce antibiotic efficacy. Together, these natural compounds represent a novel source of possible otoprotective drugs that may offer therapeutic options for patients receiving aminoglycoside treatment.

Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity

PubMed Central

Kruger, Matthew; Boney, Robert; Ordoobadi, Alexander J.; Sommers, Thomas F.; Trapani, Josef G.; Coffin, Allison B.

2016-01-01

Moderate to severe hearing loss affects 360 million people worldwide and most often results from damage to sensory hair cells. Hair cell damage can result from aging, genetic mutations, excess noise exposure, and certain medications including aminoglycoside antibiotics. Aminoglycosides are effective at treating infections associated with cystic fibrosis and other life-threatening conditions such as sepsis, but cause hearing loss in 20–30% of patients. It is therefore imperative to develop new therapies to combat hearing loss and allow safe use of these potent antibiotics. We approach this drug discovery question using the larval zebrafish lateral line because zebrafish hair cells are structurally and functionally similar to mammalian inner ear hair cells and respond similarly to toxins. We screened a library of 502 natural compounds in order to identify novel hair cell protectants. Our screen identified four bisbenzylisoquinoline derivatives: berbamine, E6 berbamine, hernandezine, and isotetrandrine, each of which robustly protected hair cells from aminoglycoside-induced damage. Using fluorescence microscopy and electrophysiology, we demonstrated that the natural compounds confer protection by reducing antibiotic uptake into hair cells and showed that hair cells remain functional during and after incubation in E6 berbamine. We also determined that these natural compounds do not reduce antibiotic efficacy. Together, these natural compounds represent a novel source of possible otoprotective drugs that may offer therapeutic options for patients receiving aminoglycoside treatment. PMID:27065807

In vivo delivery of recombinant human growth hormone from genetically engineered human fibroblasts implanted within Baxter immunoisolation devices.

PubMed

Josephs, S F; Loudovaris, T; Dixit, A; Young, S K; Johnson, R C

1999-01-01

Continuous delivery of therapeutic peptide to the systemic circulation would be the optimal treatment for a variety of diseases. The Baxter TheraCyte system is a membrane encapsulation system developed for implantation of tissues, cells such as endocrine cells or cell lines genetically engineered for therapeutic peptide delivery in vivo. To demonstrate the utility of this system, cell lines were developed which expressed human growth hormone (hGH) at levels exceeding 1 microgram per million cells per day. These were loaded into devices which were then implanted into juvenile nude rats. Significant levels of hGH of up to 2.5 ng/ml were detected in plasma throughout the six month duration of the study. In contrast, animals implanted with free cells showed peak plasma levels of 0.5 to 1.2 ng four days after implantation with no detectable hGH beyond 10 days. Histological examination of explanted devices showed they were vascularized and contained cells that were viable and morphologically healthy. After removal of the implants, no hGH could be detected which confirmed that the source of hGH was from cells contained within the device. The long term expression of human growth hormone as a model peptide has implications for the peptide therapies for a variety of human diseases using membrane encapsulated cells.

The Haematological Malignancy Research Network (HMRN): a new information strategy for population based epidemiology and health service research

PubMed Central

Smith, Alexandra; Roman, Eve; Howell, Debra; Jones, Richard; Patmore, Russell; Jack, Andrew

2010-01-01

The Haematological Malignancy Research Network (HMRN) was established in 2004 to provide robust generalizable data to inform clinical practice and research. It comprises an ongoing population-based cohort of patients newly diagnosed by a single integrated haematopathology laboratory in two adjacent UK Cancer Networks (population 3·6 million). With an emphasis on primary-source data, prognostic factors, sequential treatment/response history, and socio-demographic details are recorded to clinical trial standards. Data on 8131 patients diagnosed over the 4 years 2004–08 are examined here using the latest World Health Organization classification. HMRN captures all diagnoses (adult and paediatric) and the diagnostic age ranged from 4 weeks to 99 years (median 70·4 years). In line with published estimates, first-line clinical trial entry varied widely by disease subtype and age, falling from 59·5% in those aged <15 years to 1·9% in those aged over 75 years – underscoring the need for contextual population-based treatment and response data of the type collected by HMRN. The critical importance of incorporating molecular and prognostic markers into comparative survival analyses is illustrated with reference to diffuse-large B-cell lymphoma, acute myeloid leukaemia and myeloma. With respect to aetiology, several descriptive factors are highlighted and discussed, including the unexplained male predominance evident for most subtypes across all ages. PMID:19958356

THE SOUTHERN ARGENTINA AGILE METEOR RADAR ORBITAL SYSTEM (SAAMER-OS): AN INITIAL SPORADIC METEOROID ORBITAL SURVEY IN THE SOUTHERN SKY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Janches, D.; Swarnalingam, N.; Close, S.

2015-08-10

We present an initial survey in the southern sky of the sporadic meteoroid orbital environment obtained with the Southern Argentina Agile MEteor Radar (SAAMER) Orbital System (OS), in which over three-quarters of a million orbits of dust particles were determined from 2012 January through 2015 April. SAAMER-OS is located at the southernmost tip of Argentina and is currently the only operational radar with orbit determination capability providing continuous observations of the southern hemisphere. Distributions of the observed meteoroid speed, radiant, and heliocentric orbital parameters are presented, as well as those corrected by the observational biases associated with the SAAMER-OS operatingmore » parameters. The results are compared with those reported by three previous surveys performed with the Harvard Radio Meteor Project, the Advanced Meteor Orbit Radar, and the Canadian Meteor Orbit Radar, and they are in agreement with these previous studies. Weighted distributions for meteoroids above the thresholds for meteor trail electron line density, meteoroid mass, and meteoroid kinetic energy are also considered. Finally, the minimum line density and kinetic energy weighting factors are found to be very suitable for meteroid applications. The outcomes of this work show that, given SAAMER’s location, the system is ideal for providing crucial data to continuously study the South Toroidal and South Apex sporadic meteoroid apparent sources.« less

Honey Lake Power Facility under construction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-12-01

Geothermal energy and wood waste are primary energy sources for the 30 megawatt, net, Honey Lake Power Facility, a cogeneration power plant. The facility 60% completed in January 1989, will use 1,300 tons per day of fuel obtained from selective forest thinnings and from logging residue combined with mill wastes. The power plant will be the largest industrial facility to use some of Lassen County's geothermal resources. The facility will produce 236 million kilowatt-hours of electricity annually. The plant consists of a wood-fired traveling grate furnace with a utility-type high pressure boiler. Fluids from a geothermal well will pass throughmore » a heat exchange to preheat boiler feedwater. Used geothermal fluid will be disposed of in an injection well. Steam will be converted to electrical power through a 35.5-megawatt turbine generator and transmitted 22 miles to Susanville over company-owned and maintained transmission lines. The plant includes pollution control for particulate removal, ammonia injection for removal of nitrogen oxides, and computer-controlled combustion systems to control carbon monoxide and hydrocarbons. The highly automated wood yard consists of systems to remove metal, handle oversized material, receive up to six truck loads of wood products per hour, and continuously deliver 58 tons per hour of fuel through redundant systems to ensure maximum on-line performance. The plant is scheduled to become operational in mid-1989.« less

Water Treatment Technologies Inspire Healthy Beverages

NASA Technical Reports Server (NTRS)

2013-01-01

Mike Johnson, a former technician at Johnson Space Center, drew on his expertise as a wastewater engineer to create a line of kombucha-based probiotic drinks. Unpeeled Inc., based in Minneapolis-St. Paul, Minnesota, employs 12 people and has sold more than 6 million units of its NASA-inspired beverage.

Sequenced sorghum mutant library- an efficient platform for discovery of causal gene mutations

USDA-ARS?s Scientific Manuscript database

Ethyl methanesulfonate (EMS) efficiently generates high-density mutations in genomes. We applied whole-genome sequencing to 256 phenotyped mutant lines of sorghum (Sorghum bicolor L. Moench) to 16x coverage. Comparisons with the reference sequence revealed >1.8 million canonical EMS-induced G/C to A...

Morpho-physiological parameters affecting iron deficiency chlorosis response in soybean (Glycine max L.)

USDA-ARS?s Scientific Manuscript database

Iron deficiency chlorosis (IDC) leads to severe leaf chlorosis, low photosynthetic rates, and yield reductions of several million metric tons each year. In order to devise breeding and genetic transformation programs that aim at generating high-yielding and IDC-tolerant soybean lines, it is necessar...

No Wires.

ERIC Educational Resources Information Center

DeLoughry, Thomas J.

1995-01-01

The University of California at Santa Cruz has completed a successful test of a wireless computer network that would enable students and professors to get on line from anywhere on campus. The network, linked by radio waves, could save millions of dollars in campus wiring costs and would better meet student and faculty information needs. (MSE)

Breaking up the transcription logjam can improve cash flow.

PubMed

Paulik, Dennis

2004-06-01

Using more than 20 transcription companies to handle its annual volume of 36 million lines, Health Midwest knew it had to gain control of the document transcription and delivery process. By centralizing its transcription service, the organization saved $600,000 and reduced days in accounts receivable by 10 days.

"What Works" Research Site Unveiled

ERIC Educational Resources Information Center

Viadero, Debra

2004-01-01

After nearly two years in development, a new federally backed research service on "what works" in education began rolling its first products off the assembly line. Launched with $18.5 million in funding from the U.S. Department of Education, the newly operational What Works Clearinghouse is the department's electronic version of a "Consumer…

Nanoscale shift of the intensity distribution of dipole radiation.

PubMed

Shu, Jie; Li, Xin; Arnoldus, Henk F

2009-02-01

The energy flow lines (field lines of the Poynting vector) for radiation emitted by a dipole are in general curves, rather than straight lines. For a linear dipole the field lines are straight, but when the dipole moment of a source rotates, the field lines wind numerous times around an axis, which is perpendicular to the plane of rotation, before asymptotically approaching a straight line. We consider an elliptical dipole moment, representing the most general state of oscillation, and this includes the linear dipole as a special case. Due to the spiraling near the source, for the case of a rotating dipole moment, the field lines in the far field are displaced with respect to the outward radial direction, and this leads to a shift of the intensity distribution of the radiation in the far field. This shift is shown to be independent of the distance to the source and, although of nanoscale dimension, should be experimentally observable.

Green, Clean, & Mean: Pushing the Energy Envelope in Tech Industry Buildings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mills, Evan; Granderson, Jessica; Chan, Rengie

When it comes to innovation in energy and building performance, one can expect leading-edge activity from the technology sector. As front-line innovators in design, materials science, and information management, developing and operating high-performance buildings is a natural extension of their core business. The energy choices made by technology companies have broad importance given their influence on society at large as well as the extent of their own energy footprint. Microsoft, for example, has approximately 250 facilities around the world (30 million square feet of floor area), with significant aggregate energy use of approximately 4 million kilowatt-hours per day (Figure 1).

Wildfire-related deaths--Texas, March 12-20, 2006.

PubMed

2007-08-03

During March 12-20, 2006, wildfires burned approximately 1 million acres in the Panhandle region of Texas, advancing 45 miles in 9 hours, with dense smoke and flames up to 11 feet. The two largest fires, which together extended into nine counties, resulted from power lines downed by sustained winds of 46 mph and gusts up to 53 mph. The wildfires destroyed more than 89 structures, with losses estimated at $16 million. The fires caused evacuations in eight communities with a total population of 4,072. This report summarizes the circumstances of 12 deaths and describes the five separate incidents caused by the two wildfires that resulted in those deaths.

Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines

DTIC Science & Technology

2012-01-01

conditions (mean of 471.16 pmoles per 10 million cells) during a period of 15 minutes was able to account for about 18% and more than 30...of 85.64 pmoles per 10 million cells) during a period of 15 minutes was able to account for about 15% andmore than 17%, respectively, of the total...least one common explanation for the changes in intraspinal bio- chemistry to account for the chronic pain that they produce, 22 Pain Research and

Urologic diseases in America Project: analytical methods and principal findings.

PubMed

Litwin, Mark S; Saigal, Christopher S; Yano, Elizabeth M; Avila, Chantal; Geschwind, Sandy A; Hanley, Jan M; Joyce, Geoffrey F; Madison, Rodger; Pace, Jennifer; Polich, Suzanne M; Wang, Mingming

2005-03-01

The burden of urological diseases on the American public is immense in human and financial terms but it has been under studied. We undertook a project, Urologic Diseases in America, to quantify the burden of urological diseases on the American public. We identified public and private data sources that contain population based data on resource utilization by patients with benign and malignant urological conditions. Sources included the Centers for Medicare and Medicaid Services, National Center for Health Statistics, Medical Expenditure Panel Survey, National Health and Nutrition Examination Survey, Department of Veterans Affairs, National Association of Children's Hospitals and Related Institutions, and private data sets maintained by MarketScan Health and Productivity Management (MarketScan, Chichester, United Kingdom), Ingenix (Ingenix, Salt Lake City, Utah) and Center for Health Care Policy and Evaluation. Using diagnosis and procedure codes we described trends in the utilization of urological services. In 2000 urinary tract infections accounted for more than 6.8 million office visits and 1.3 million emergency room visits, and 245,000 hospitalizations in women with an annual cost of more than 2.4 billion dollars. Urinary tract infections accounted for more than 1.4 million office visits, 424,000 emergency room visits and 121,000 hospitalizations in men with an annual cost of more than 1 billion dollars. Benign prostatic hyperplasia was the primary diagnosis in more than 4.4 million office visits, 117,000 emergency room visits and 105,000 hospitalizations, accounting for 1.1 billion dollars in expenditures that year. Urolithiasis was the primary diagnosis for almost 2 million office visits, more than 600,000 emergency room visits, and more than 177,000 hospitalizations, totaling more than 2 billion dollars in annual expenditures. Urinary incontinence in women was the primary cause for more than 1.1 million office visits in 2000 and 452 million dollars in aggregate primary cause for more than 1.1 million office visits in 2000 and 452 million dollars in aggregate annual expenditures. Other manuscripts in this series present further detail for specific urologic conditions. Recent trends in epidemiology, practice patterns, resource utilization and costs for urological diseases have broad implications for quality of health care, access to care and the equitable allocation of scarce resources for clinical care and research.

On the Non-Equilibrium Population Distribution of E-Methanol in Dark Clouds

NASA Astrophysics Data System (ADS)

Wollman, Emma

2007-12-01

The goal of this project was to determine the typical distribution of rotational level populations in the k=0 ladder of E-methanol in dark clouds in order to provide another observational test for theoretical models of pumping. We used our own observations of several sources with the 12-m ARO telescope on Kitt Peak as well as the published observational results by Slysh et al. (1999). The relative level populations (excitation temperatures) were determined from the measured intensity ratios of a series of the J(0)-J(-1) transitions of E-methanol under the assumption of spontaneous, optically thin emission. We observed the J(0)-J(-1) lines in six sources: W75N, DR21N, DR21, and three positions at DR21OH. The J=1 to J=5 lines were observed for all sources and the J=7 line was observed for W75N, DR21N, and one position in DR21OH. We also used Slysh et al.'s results for the J=1 through 4 lines in 52 sources, for the J=5 line in 50 sources, for the J=6 line in 15 sources, and for the J=7 and 8 lines in 2 sources. We determined the excitation temperatures of the involved levels in the k=0 ladder relative to the 1(0) level for each source and averaged the results over the sources. The average excitation temperatures demonstrate strong evidence of overcooling in the k=0 ladder - the excitation temperature increases linearly with increasing energy, from 8 K to 35 K. Our observations confirm this tendency of overcooling. We will discuss the agreement of these results with the predictions of the current models of methanol pumping. The author thanks the technical staff of the 12-m ARO telescope for help with the observations. This project was supported by the NSF/REU grant AST-0354056 and the Nantucket Maria Mitchell Association.

Water withdrawal and use in Maryland, 1986

USGS Publications Warehouse

Wheeler, J.C.

1990-01-01

During 1986, about 1,460 million gallons per day of freshwater was withdrawn from the surface-, and groundwater resources of Maryland. In addition, more than 6,240 million gallons per day of saline surface water was withdrawn and used primarily for cooling purposes in the generation of electricity. Most freshwater withdrawals (84%) were from surface water sources and were withdrawn and used in the Potomac drainage basin, whereas most groundwater was withdrawn and used in the Upper Chesapeake drainage basin. The Potomac Group aquifers provided the most groundwater (56 million gallons per day). Ten water use categories comprise the major demands on the surface and groundwater resources of the State: public supply, domestic, commercial, industrial, mining, thermoelectric power generation, hydroelectric power generation, agricultural (non-irrigation), irrigation, and aquaculture. Public-supply systems withdrew the most water in the State (801 million gallon/day) for use by residents, commercial establishments, and industries. Baltimore City had the largest public-supply use in 1986 (about 151 million gallons/day). (USGS)

A longitudinal dataset of five years of public activity in the Scratch online community.

PubMed

Hill, Benjamin Mako; Monroy-Hernández, Andrés

2017-01-31

Scratch is a programming environment and an online community where young people can create, share, learn, and communicate. In collaboration with the Scratch Team at MIT, we created a longitudinal dataset of public activity in the Scratch online community during its first five years (2007-2012). The dataset comprises 32 tables with information on more than 1 million Scratch users, nearly 2 million Scratch projects, more than 10 million comments, more than 30 million visits to Scratch projects, and more. To help researchers understand this dataset, and to establish the validity of the data, we also include the source code of every version of the software that operated the website, as well as the software used to generate this dataset. We believe this is the largest and most comprehensive downloadable dataset of youth programming artifacts and communication.

Photographer : JPL Range : 7 million kilometers (5 million miles) Callisto is Jupiter's outermost

NASA Technical Reports Server (NTRS)

1979-01-01

Photographer : JPL Range : 7 million kilometers (5 million miles) Callisto is Jupiter's outermost Galilean satellites and darkest of the four(but almost twice as bright as Earth's Moon). Mottled appearance from bright and dark patches. Bright spots seem like rayed or bright halved craters seen on our Moon. This face is always turned toward Jupiter. Photo taken through violet filter. Ganymede is slightly larger than Mercury but much less dense (twice the density of water). Its surface brightness is 4 times of Earth's Moon. Mare regions (dark features) are like the Moon's but have twice the brightness, and believed to be unlikely of rock or lava as the Moon's are. It's north pole seems covered with brighter material and may be water frost. Scattered brighter spots may be related to impact craters or source of fresh ice.

Metal Hydride and Alkali Halide Opacities in Extrasolar Giant Planets and Cool Stellar Atmospheres

NASA Technical Reports Server (NTRS)

Weck, Philippe F.; Stancil, Phillip C.; Kirby, Kate; Schweitzer, Andreas; Hauschildt, Peter H.

2006-01-01

The lack of accurate and complete molecular line and continuum opacity data has been a serious limitation to developing atmospheric models of cool stars and Extrasolar Giant Planets (EGPs). We report our recent calculations of molecular opacities resulting from the presence of metal hydrides and alkali halides. The resulting data have been included in the PHOENIX stellar atmosphere code (Hauschildt & Baron 1999). The new models, calculated using spherical geometry for all gravities considered, also incorporate our latest database of nearly 670 million molecular lines, and updated equations of state.

The soft X-ray polychromator for the Solar Maximum Mission

NASA Technical Reports Server (NTRS)

Acton, L. W.; Finch, M. L.; Gilbreth, C. W.; Culhane, J. L.; Bentley, R. D.; Bowles, J. A.; Guttridge, P.; Gabriel, A. H.; Firth, J. G.; Hayes, R. W.

1980-01-01

The paper considers the soft X-ray polychromator (XRP) operating in the 1.4-22.4 A range of the soft X-ray spectrum which includes many emission lines important for the diagnosis of plasmas in the 1.5-50 million deg temperature range. The flat crystal scanning spectrometer provides for a channel polychromatic mapping of flares and active regions in the resonance lines of O VIII, Ne IX, and Mg XI; in its spectral scanning mode it covers essentially the entire 1.4-22.5 A region.

The soft X-ray polychromator for the Solar Maximum Mission

NASA Astrophysics Data System (ADS)

Acton, L. W.; Culhane, J. L.; Gabriel, A. H.; Bentley, R. D.; Bowles, J. A.; Firth, J. G.; Finch, M. L.; Gilbreth, C. W.; Guttridge, P.; Hayes, R. W.; Joki, E. G.; Jones, B. B.; Kent, B. J.; Leibacher, J. W.; Nobles, R. A.; Patrick, T. J.; Phillips, K. J. H.; Rapley, C. G.; Sheather, P. H.; Sherman, J. C.; Stark, J. P.; Springer, L. A.; Turner, R. F.; Wolfson, C. J.

1980-02-01

The paper considers the soft X-ray polychromator (XRP) operating in the 1.4-22.4 A range of the soft X-ray spectrum which includes many emission lines important for the diagnosis of plasmas in the 1.5-50 million deg temperature range. The flat crystal scanning spectrometer provides for a channel polychromatic mapping of flares and active regions in the resonance lines of O VIII, Ne IX, and Mg XI; in its spectral scanning mode it covers essentially the entire 1.4-22.5 A region.

Geochemical evaluation of part of the Cambay basin, India

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banerjee, A.; Rao, K.L.N.

1993-01-01

In Broach-Jambusar and Ahmedabad-Mehsana blocks of Cambay basin, India, the hydrocarbon generated (HCG) and hydrocarbon expelled (HCE) per unit area of four Paleogene formations were computed at 38 locations to select the best targets and thus reduce exploration risk. Fractional generation curves, which show relation between vitrinite reflectance and fraction of original generative potential converted to hydrocarbons, were constructed for study areas and used to calculate HCG through remaining generation potential (S[sub 2] of Rock-Eval) and the thickness of the sedimentary section. HCE was estimated by subtracting volatile hydrocarbon content (S[sub 1] of Rock-Eval), representing the unexpelled in-situ-generated bitumen, frommore » the computed value of HCG. HCG and HCE, which combine source rock richness, thickness, and maturity, are useful for comparative evaluation of charging capacity of source rocks. Positive and negative HCEs characterize drainage and accumulation locales, respectively. In the study areas, the major generative depressions are at Sobhasan/Linch/Wadu and Ahmedabad in the Ahmedabad-Mehsana block and the Tankari and Broach depressions in the Broach-Jambusar block. In these areas, Paleogene source rocks have generated between 3 million and 12 million MT hydrocarbon/km[sup 2]. The major known oil and gas accumulations, which are in middle to lower Eocene sandstones in vicinity of the generative depressions, overlie 2 million to 7 million MT hydrocarbon/km[sup 2] and HCG contours in both blocks and correlate well with negative HCE in the reservoir. Isopach maps of several major middle to lower Eocene reservoir sandstones in conjunction with HCG maps for Paleogene section help to delineate favorable exploration locales. 23 refs., 31 figs.« less

RLINE: A Line Source Dispersion Model for Near-Surface Releases

EPA Science Inventory

This paper describes the formulation and evaluation of RLINE, a Research LINE source model for near surface releases. The model is designed to simulate mobile source pollutant dispersion to support the assessment of human exposures in near-roadway environments where a significant...

Hydrocephalus research funding from the National Institutes of Health: a 10-year perspective.

PubMed

Gross, Paul; Reed, Gavin T; Engelmann, Rachel; Kestle, John R W

2014-02-01

Funding of hydrocephalus research is important to the advancement of the field. The goal of this paper is to describe the funding of hydrocephalus research from the National Institutes of Health (NIH) over a recent 10-year period. The NIH online database RePORT (Research Portfolio Online Reporting Tools) was searched using the key word "hydrocephalus." Studies were sorted by relevance to hydrocephalus. The authors analyzed funding by institute, grant type, and scientific approach over time. Over $54 million was awarded to 59 grantees for 66 unique hydrocephalus proposals from 48 institutions from 2002 to 2011. The largest sources of funding were the National Institute of Neurological Disease and Stroke and the National Institute of Child Health and Human Development. Of the total, $22 million went to clinical trials, $15 million to basic science, and $10 million to joint ventures with small business (Small Business Innovation Research or Small Business Technology Transfer). Annual funding varied from $2.3 to $8.1 million and steadily increased in the second half of the observation period. The number of new grants also went from 15 in the first 5 years to 27 in the second 5 years. A large portion of the funding has been for clinical trials. Funding for shunt-device development grew substantially. Support for training of hydrocephalus investigators has been low. Hydrocephalus research funding is low compared with that for other conditions of similar health care burden. In addition to NIH applications, researchers should pursue other funding sources. Small business collaborations appear to present an opportunity for appropriate projects.

Line plus arc source trajectories and their R-line coverage for long-object cone-beam imaging with a C-arm system

NASA Astrophysics Data System (ADS)

Yu, Zhicong; Wunderlich, Adam; Dennerlein, Frank; Lauritsch, Günter; Noo, Frédéric

2011-06-01

Cone-beam imaging with C-arm systems has become a valuable tool in interventional radiology. Currently, a simple circular trajectory is used, but future applications should use more sophisticated source trajectories, not only to avoid cone-beam artifacts but also to allow extended volume imaging. One attractive strategy to achieve these two goals is to use a source trajectory that consists of two parallel circular arcs connected by a line segment, possibly with repetition. In this work, we address the question of R-line coverage for such a trajectory. More specifically, we examine to what extent R-lines for such a trajectory cover a central cylindrical region of interest (ROI). An R-line is a line segment connecting any two points on the source trajectory. Knowledge of R-line coverage is crucial because a general theory for theoretically exact and stable image reconstruction from axially truncated data is only known for the points in the scanned object that lie on R-lines. Our analysis starts by examining the R-line coverage for the elemental trajectories consisting of (i) two parallel circular arcs and (ii) a circular arc connected orthogonally to a line segment. Next, we utilize our understanding of the R-lines for the aforementioned elemental trajectories to determine the R-line coverage for the trajectory consisting of two parallel circular arcs connected by a tightly fit line segment. For this trajectory, we find that the R-line coverage is insufficient to completely cover any central ROI. Because extension of the line segment beyond the circular arcs helps to increase the R-line coverage, we subsequently propose a trajectory composed of two parallel circular arcs connected by an extended line. We show that the R-lines for this trajectory can fully cover a central ROI if the line extension is long enough. Our presentation includes a formula for the minimum line extension needed to achieve full R-line coverage of an ROI with a specified size, and also includes a preliminary study on the required detector size, showing that the R-lines added by the line extension are not constraining.

Use of Oil Palm Waste as a Renewable Energy Source and Its Impact on Reduction of Air Pollution in Context of Malaysia

NASA Astrophysics Data System (ADS)

Begum, Shahida; P, Kumaran; M, Jayakumar

2013-06-01

One of the most efficient and effective solutions for sustainable energy supply to supplement the increasing energy demand and reducing environment pollution is renewable energy resources. Malaysia is currently the world's second largest producer and exporter of palm oil and 47% of the world's supply of palm oil is produced by this country. Nearly 80 million tonnes of Fresh Fruit Bunches (FFB) are processed annually in 406 palm oil mills and are generating approximately 54 million tonnes of palm oil mill effluent (POME), known to generate biogas consisting of methane - a Green House Gas (GHG) identifiable to cause global warming. This is 21 times more potent GHG than CO2. These two major oil palm wastes are a viable renewable energy (RE) source for production of electricity. If the two sources are used in harnessing the renewable energy potential the pollution intensity from usage of non-renewable sources can also be reduced significantly. This study focused on the pollution mitigation potential of biogas as biogas is a renewable energy. Utilization of this renewable source for the production of electricity is believed to reduce GHG emissions to the atmosphere.

Phase 3 experiments of the JAERI/USDOE collaborative program on fusion blanket neutronics. Volume 1: Experiment

NASA Astrophysics Data System (ADS)

Oyama, Yukio; Konno, Chikara; Ikeda, Yujiro; Maekawa, Fujio; Kosako, Kazuaki; Nakamura, Tomoo; Maekawa, Hiroshi; Youssef, Mahmoud Z.; Kumar, Anil; Abdou, Mohamed A.

1994-02-01

A pseudo-line source has been realized by using an accelerator based D-T point neutron source. The pseudo-line source is obtained by time averaging of continuously moving point source or by superposition of finely distributed point sources. The line source is utilized for fusion blanket neutronics experiments with an annular geometry so as to simulate a part of a tokamak reactor. The source neutron characteristics were measured for two operational modes for the line source, continuous and step-wide modes, with the activation foil and the NE213 detectors, respectively. In order to give a source condition for a successive calculational analysis on the annular blanket experiment, the neutron source characteristics was calculated by a Monte Carlo code. The reliability of the Monte Carlo calculation was confirmed by comparison with the measured source characteristics. The shape of the annular blanket system was a rectangular with an inner cavity. The annular blanket was consist of 15 mm-thick first wall (SS304) and 406 mm-thick breeder zone with Li2O at inside and Li2CO3 at outside. The line source was produced at the center of the inner cavity by moving the annular blanket system in the span of 2 m. Three annular blanket configurations were examined; the reference blanket, the blanket covered with 25 mm thick graphite armor and the armor-blanket with a large opening. The neutronics parameters of tritium production rate, neutron spectrum and activation reaction rate were measured with specially developed techniques such as multi-detector data acquisition system, spectrum weighting function method and ramp controlled high voltage system. The present experiment provides unique data for a higher step of benchmark to test a reliability of neutronics design calculation for a realistic tokamak reactor.

Prediction of ppm level electrical failure by using physical variation analysis

NASA Astrophysics Data System (ADS)

Hou, Hsin-Ming; Kung, Ji-Fu; Hsu, Y.-B.; Yamazaki, Y.; Maruyama, Kotaro; Toyoshima, Yuya; Chen, Chu-en

2016-03-01

The quality of patterns printed on wafer may be attributed to factors such as process window control, pattern fidelity, overlay performance, and metrology. Each of these factors play an important role in making the process more effective by ensuring that certain design- and process-specific parameters are kept within acceptable variation. Since chip size and pattern density are increasing accordingly, in-line real time catching the in-chip weak patterns/defects per million opportunities (WP-DPMO) plays more and more significant role for product yield with high density memory. However, the current in-line inspection tools focus on single layer defect inspection, not effectively and efficiently to catch multi-layer weak patterns/defects even through voltage contrast and/or special test structure design [1]-[2]. In general, the multi-layer weak patterns/defects are escaped easily by using in-line inspection and cause ignorance of product dysfunction until off-line time-consuming final PFA/EFA will be used. To effectively and efficiently in-line real time monitor the potential multi-layer weak patterns, we quantify the bridge electrical metric between contact and gate electrodes into CD physical metric via big data from the larger field of view (FOV: 8k x 16k with 3 nm pixel equalizes to image main field size 34 um x 34 um @ 3 nm pixel) e-beam quality image contour compared to layout GDS database (D2DB) as shown in Fig. 1. Hadoop-based distributed parallel computing is implemented to improve the performance of big data architectures, Fig. 2. Therefore, the state of art in-line real time catching in-chip potential multi-layer weak patterns can be proven and achieved by following some studying cases [3]. Therefore, manufacturing sources of variations can be partitioned to systematic and random variations by applying statistical techniques based on the big data fundamental infrastructures. After big data handling, the in-chip CD and AA variations are distinguished by their spatial correlation distance. For local variations (LV) there is no correlation, whereas for global variations (GV) the correlation distance is very large [7]-[9]. This is the first time to certificate the validation of spatial distribution from the affordable bias contour big data fundamental infrastructures. And then apply statistical techniques to dig out the variation sources. The GV come from systematic issue, which could be compensated by adaptive LT condition or OPC correction. But LV comes from random issue, which being considered as intrinsic problem such as structure, material, tool capability… etc. In this paper studying, we can find out the advanced technology node SRAM contact CD local variation (LV) dominates in total variation, about 70%. It often plays significant in-line real time catching WP-DPMO role of the product yield loss, especially for wafer edge is the worst loss within wafer distribution and causes serious reliability concern. The major root cause of variations comes from the PR material induced burr defect (LV), the second one comes from GV enhanced wafer edge short opportunity, which being attributed to three factors, first one factor is wafer edge CD deliberated enlargement for yield improvement as shown in Fig. 10. Second factor is overlaps/AA shifts due to tool capability dealing with incoming wafer's war page issue and optical periphery layout dependent working pitch issue as shown in Fig. 9 (1)., the last factor comes from wafer edge burr enhanced by wafer edge larger Photo Resistance (PR) spin centrifugal force. After implementing KPIs such as GV related AA/CD indexes as shown in Fig. 9 (1) and 10, respectively, and LV related burr index as shown in Fig. 11., we can construct the parts per million (PPM) level short probability model via multi-variables regression, canonical correlation analysis and logistic transformation. The model provides prediction of PPM level electrical failure by using in-line real time physical variation analysis. However in order to achieve Total Quality Management (TQM), the adaptive Statistical Process Control (SPC) charts can be implemented to in-line real time catch PPM level product malfunction at manufacturing stage. Applying for early stage monitor likes incoming raw material, Photo Resistance (PR) … etc., the LV related burr KPI SPC charts could be a powerful quality inspection vehicle. To sum up the paper's contributions, the state of art in-line real time catching in-chip potential multi-layer physical weak patterns can be proven and achieved effectively and efficiently to associate with PPM level product dysfunction.

ExoMol line lists - XXIX. The rotation-vibration spectrum of methyl chloride up to 1200 K

NASA Astrophysics Data System (ADS)

Owens, A.; Yachmenev, A.; Thiel, W.; Fateev, A.; Tennyson, J.; Yurchenko, S. N.

2018-06-01

Comprehensive rotation-vibration line lists are presented for the two main isotopologues of methyl chloride, 12CH335Cl and 12CH337Cl. The line lists, OYT-35 and OYT-37, are suitable for temperatures up to T = 1200 K and consider transitions with rotational excitation up to J = 85 in the wavenumber range 0-6400 cm-1 (wavelengths λ > 1.56 μm). Over 166 billion transitions between 10.2 million energy levels have been calculated variationally for each line list using a new empirically refined potential energy surface, determined by refining to 739 experimentally derived energy levels up to J = 5, and an established ab initio dipole moment surface. The OYT line lists show excellent agreement with newly measured high-temperature infrared absorption cross-sections, reproducing both strong and weak intensity features across the spectrum. The line lists are available from the ExoMol database and the CDS database.

Alternative Funding Sources for Migrant Education.

ERIC Educational Resources Information Center

Binder, Eugene

Despite 1983 Elementary and Secondary Education ACT (ESEA) Title I federal funding of over $255 million for more than 3,000 projects for some 600,000 migrant children and youth, there is still need for alternate funding sources to overcome spiraling inflation and increasing program costs and numbers of eligible children. Other federal, state,…

40 CFR 421.245 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... existing sources. The mass of wastewater pollutants in secondary nickel process wastewater introduced into.../kg (pounds per million pounds) of slag input to reclaim process Chromium (total) 5.653 2.313 Copper 24.410 12.850 Nickel 24.670 16.320 (b) Acid reclaim leaching filtrate. PSES for the Secondary Nickel...

75 FR 53269 - Federal Acquisition Regulation; Tribal Consultation; Justification and Approval of Sole-Source 8...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-31

... Administration (NASA). ACTION: Notice of tribal consultation and outreach meetings and request for comments... owned by Indian Tribes and Alaska Native Corporations, if the sole-source award is to exceed $20 million... Indian Tribes and Alaska Native Corporations. As explained in E.O. 13175, Tribal consultation is a...

The Joint Effects-Based Contracting Execution System: A Proposed Enabling Concept for Future Joint Expeditionary Contracting Execution

DTIC Science & Technology

2008-12-01

average 1 hour per response, including the time for reviewing instruction, searching existing data sources , gathering and maintaining the data needed...Representative for the Contracting Officer on five contracts whose value xii exceeded $200 million and participated on four source selection committees...roles on source selection boards; Consolidated Husbanding Services for all Pacific Ports, Consolidated MWR services for the Pacific, Software

Cost-effectiveness analysis of KRAS testing and cetuximab as last-line therapy for colorectal cancer.

PubMed

Shiroiwa, Takeru; Motoo, Yoshiharu; Tsutani, Kiichiro

2010-12-01

Cetuximab, a monoclonal antibody directed against the epidermal growth factor receptor, improves progression-free survival and overall survival in patients with metastatic colorectal cancer (mCRC). However, patients with a KRAS gene mutation do not benefit from cetuximab therapy. We performed a cost-effectiveness analysis of KRAS testing and cetuximab treatment as last-line therapy for patients with mCRC in Japan. In our analysis, we considered three treatment strategies. In the 'KRAS-testing strategy' (strategy A), KRAS testing was performed to guide treatment: patients with wild-type KRAS received cetuximab, and those with mutant KRAS received best supportive care (BSC). In the 'no-KRAS-testing strategy' (strategy B), genetic testing was not conducted and all patients received cetuximab. In the 'no-cetuximab strategy' (strategy C), genetic testing was not conducted and all patients received BSC. To evaluate the cost effectiveness of KRAS testing, the KRAS-testing strategy was compared with the no-KRAS-testing strategy; to evaluate the cost effectiveness of KRAS testing and cetuximab, the KRAS-testing strategy was compared with the no-cetuximab strategy; and to evaluate the cost effectiveness of cetuximab treatment without KRAS testing, the no-KRAS-testing strategy was compared with the no-cetuximab strategy. A three-state Markov model was used to predict expected costs and outcomes for each group. Outcomes in the model were based on those reported in a retrospective analysis of data from the National Cancer Institute of Canada Clinical Trials Group CO.17 study. We included only direct medical costs from the perspective of the Japanese healthcare payer. A 3% discount rate was used for both costs and outcome. Two outcomes, life-years (LYs) gained and quality-adjusted life-years (QALYs) gained, were used to calculate the incremental cost-effectiveness ratio (ICER). Our cost-effectiveness analysis revealed that the KRAS-testing strategy was dominant compared with the no-KRAS-testing strategy, with an expected cost reduction of ¥0.5 million per patient and an estimated budget impact of ¥3-5 billion ($US42-59 million; July 2010 values) per year. The ICER of the KRAS-testing strategy compared with the no-cetuximab strategy was ¥11 million ($US120 000) per LY gained and ¥16 million ($US160 000) per QALY gained, whereas the ICER of the KRAS-testing strategy compared with the no-KRAS-testing strategy was ¥14 million ($US180 000) per LY gained and ¥21 million ($US230 000) per QALY gained. These results were supported by the sensitivity analysis. KRAS testing is recommended before administering cetuximab as last-line therapy for patients with mCRC. However, our analysis suggests that the ICER of cetuximab treatment (with or without KRAS testing) is too high, even if treatment is limited to patients with wild-type KRAS.

Maize aflatoxin accumulation segregates with early maturing selections from an S2 breeding cross population.

PubMed

Henry, W Brien

2013-01-15

Maize breeders continue to seek new sources of aflatoxin resistance, but most lines identified as resistance sources are late maturing. The vast difference in flowering time makes it hard to cross these lines with proprietary commercial lines that mature much earlier and often subjects the reproductive phase of these resistant lines to the hottest and driest portion of the summer, making silking, pollination and grain fill challenging. Two hundred crosses from the GEM Project were screened for aflatoxin accumulation at Mississippi State in 2008, and a subset of these lines were screened again in 2009. The breeding cross UR13085:S99g99u was identified as a potential source of aflatoxin resistance, and maturity-based selections were made from an S2 breeding population from this same germplasm source: UR13085:S99g99u-B-B. The earliest maturing selections performed poorly for aflatoxin accumulation, but later maturing selections were identified with favorable levels of aflatoxin accumulation. These selections, while designated as "late" within this study, matured earlier than most aflatoxin resistant lines presently available to breeders. Two selections from this study, designated S5_L7 and S5_L8, are potential sources of aflatoxin resistance and will be advanced for line development and additional aflatoxin screening over more site years and environments.

33 CFR 183.410 - Ignition protection.

Code of Federal Regulations, 2010 CFR

2010-07-01

... both vertically and horizontally the distance of the open space between the fuel source and the... sources, such as engines, and valves, connections, or other fittings in vent lines, fill lines... component is isolated from a gasoline fuel source if: (1) A bulkhead that meets the requirements of...

Outburst of GX304-1 Monitored with INTEGRAL: Positive Correlation Between the Cyclotron Line Energy and Flux

NASA Technical Reports Server (NTRS)

Klochkov, D.; Doroshenko, V.; Santangelo, A.; Staubert, R.; Ferrigno, C.; Kretschmar, P.; Caballero, I.; Wilms, J.; Kreykenbohm, I.; Pottschmidt, I.;

Spectral lines and characteristic of temporal variations in photoionized plasmas induced with laser-produced plasma extreme ultraviolet source

NASA Astrophysics Data System (ADS)

Saber, I.; Bartnik, A.; Wachulak, P.; Skrzeczanowski, W.; Jarocki, R.; Fiedorowicz, H.

2017-11-01

Spectral lines for Kr/Ne/H2 photoionized plasma in the ultraviolet and visible (UV/Vis) wavelength ranges have been created using a laser-produced plasma (LPP) EUV source. The source is based on a double-stream gas puff target irradiated with a commercial Nd:YAG laser. The laser pulses were focused onto a gas stream, injected into a vacuum chamber synchronously with the EUV pulses. Spectral lines from photoionization in neutral Kr/Ne/H2 and up to few charged states were observed. The intense emission lines were associated with the Kr transition lines. Experimental and theoretical investigations on intensity variations for some ionic lines are presented. A decrease in the intensity with the delay time between the laser pulse and the spectrum acquisition was revealed. Electron temperature and electron density in the photoionized plasma have been estimated from the characteristic emission lines. Temperature was obtained using Boltzmann plot method, assuming that the population density of atoms and ions are considered in a local thermodynamic equilibrium (LTE). Electron density was calculated from the Stark broadening profile. The temporal evaluation of the plasma and the way of optimizing the radiation intensity of LPP EUV sources is discussed.

Ebola research funding: a systematic analysis, 1997–2015

PubMed Central

Fitchett, Joseph RA; Lichtman, Amos; Soyode, Damilola T; Low, Ariel; Villar de Onis, Jimena; Head, Michael G; Atun, Rifat

2016-01-01

Background The latest outbreak of Ebola in West Africa overwhelmed the affected countries, with the impact on health extending far beyond Ebola–related deaths that have exceeded 11 000. The need to promptly mobilise resources to control emerging infections is widely recognized. Yet, data on research funding for emerging infections remains inadequately documented. Methods We defined research investment as all funding flows for Ebola and/or Marburg virus from 1997 to April 2015 whose primary purpose was to advance knowledge and new technologies to prevent or cure disease. We sourced data directly from funding organizations and estimated the investment in 2015 US dollars (US$). Results Funding for Ebola and Marburg virus research in 1997 to 2015 amounted to US$ 1.035 billion, including US$ 435.4 million (42.0%) awarded in 2014 and 2015. Public sources of funding invested US$ 758.8 million (73.1%), philanthropic sources US$ 65.1 million (6.3%), and joint public/private/philanthropic ventures accounted for US$ 213.8 million (20.6%). Prior to the Ebola outbreak in 2014, pre–clinical research dominated research with US$ 443.6 million (73.9%) investment. After the outbreak, however, investment for new product development increased 942.7–fold and that for clinical trials rose 23.5–fold. Investment in new tools to control Ebola and Marburg virus amounted to US$ 399.1 million, with 61.3% awarded for vaccine research, 29.2% for novel therapeutics research such as antivirals and convalescent blood products, and 9.5% for diagnostics research. Research funding and bibliometric output were moderately associated (Spearman’s ρ = 0.5232, P = 0.0259), however number of Ebola cases in previous outbreaks and research funding (ρ = 0.1706, P = 0.4985) and Ebola cases in previous outbreaks and research output (ρ = 0.3020, P = 0.0616) were poorly correlated. Conclusion Significant public and philanthropic funds have been invested in Ebola and Marburg virus research in 2014 and 2015, following the outbreak in West Africa. Long term, strategic vision and leadership are needed to invest in infections with pandemic potential early, including innovative financing measures and open access investment data to promote the development of new therapies and technologies. PMID:27909582

Ebola research funding: a systematic analysis, 1997-2015.

PubMed

Fitchett, Joseph Ra; Lichtman, Amos; Soyode, Damilola T; Low, Ariel; Villar de Onis, Jimena; Head, Michael G; Atun, Rifat

2016-12-01

The latest outbreak of Ebola in West Africa overwhelmed the affected countries, with the impact on health extending far beyond Ebola-related deaths that have exceeded 11 000. The need to promptly mobilise resources to control emerging infections is widely recognized. Yet, data on research funding for emerging infections remains inadequately documented. We defined research investment as all funding flows for Ebola and/or Marburg virus from 1997 to April 2015 whose primary purpose was to advance knowledge and new technologies to prevent or cure disease. We sourced data directly from funding organizations and estimated the investment in 2015 US dollars (US$). Funding for Ebola and Marburg virus research in 1997 to 2015 amounted to US$ 1.035 billion, including US$ 435.4 million (42.0%) awarded in 2014 and 2015. Public sources of funding invested US$ 758.8 million (73.1%), philanthropic sources US$ 65.1 million (6.3%), and joint public/private/philanthropic ventures accounted for US$ 213.8 million (20.6%). Prior to the Ebola outbreak in 2014, pre-clinical research dominated research with US$ 443.6 million (73.9%) investment. After the outbreak, however, investment for new product development increased 942.7-fold and that for clinical trials rose 23.5-fold. Investment in new tools to control Ebola and Marburg virus amounted to US$ 399.1 million, with 61.3% awarded for vaccine research, 29.2% for novel therapeutics research such as antivirals and convalescent blood products, and 9.5% for diagnostics research. Research funding and bibliometric output were moderately associated (Spearman's ρ  = 0.5232, P  = 0.0259), however number of Ebola cases in previous outbreaks and research funding (ρ = 0.1706, P  = 0.4985) and Ebola cases in previous outbreaks and research output (ρ = 0.3020, P  = 0.0616) were poorly correlated. Significant public and philanthropic funds have been invested in Ebola and Marburg virus research in 2014 and 2015, following the outbreak in West Africa. Long term, strategic vision and leadership are needed to invest in infections with pandemic potential early, including innovative financing measures and open access investment data to promote the development of new therapies and technologies.

WISE Photometry for 400 million SDSS sources

DOE PAGES

Lang, Dustin; Hogg, David W.; Schlegel, David J.

2016-01-28

Here, we present photometry of images from the Wide-Field Infrared Survey Explorer (WISE) of over 400 million sources detected by the Sloan Digital Sky Survey (SDSS). We also use a "forced photometry" technique, using measured SDSS source positions, star-galaxy classification, and galaxy profiles to define the sources whose fluxes are to be measured in the WISE images. We perform photometry with The Tractor image modeling code, working on our "unWISE" coaddds and taking account of the WISE point-spread function and a noise model. The result is a measurement of the flux of each SDSS source in each WISE band. Manymore » sources have little flux in the WISE bands, so often the measurements we report are consistent with zero given our uncertainties. But, for many sources we get 3σ or 4σ measurements; these sources would not be reported by the "official" WISE pipeline and will not appear in the WISE catalog, yet they can be highly informative for some scientific questions. In addition, these small-signal measurements can be used in stacking analyses at the catalog level. The forced photometry approach has the advantage that we measure a consistent set of sources between SDSS and WISE, taking advantage of the resolution and depth of the SDSS images to interpret the WISE images; objects that are resolved in SDSS but blended together in WISE still have accurate measurements in our photometry. Our results, and the code used to produce them, are publicly available at http://unwise.me.« less

Development of the TFTR neutral beam injection system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prichard, Jr., B. A.

1977-01-01

The TFTR Neutral Beam Lines are designed to inject 20 MW of 120 keV neutral deuterium atoms into the plasma. This is accomplished using 12 sources, 65 amperes each, mounted in 4 beam lines. The 120 kV sources and a prototype beam line are being developed. The implementation of these beam lines has required the development of several associated pieces of hardware. 200 kV switch tubes for the power supplies are being developed for modulation and regulation of the accelerating supplies. A 90 cm metallic seal gate valve capable of sealing against atmosphere in either direction is being developed formore » separating the torus and beam line vacuum systems. A 70 x 80 cm fast shutter valve is also being developed to limit tritium migration from the torus into the beam line. Internal to the beam line a calorimeter, ion dump and deflection magnet have been designed to handle three beams, and optical diagnostics utilizing the doppler broadening and doppler shift of light emitted from the accelerated beam are being developed. The control and monitoring of the 12 sources will be done via the TFTR computer control system (CICADA) as will other parts of the machine, and software is being developed to condition and operate the sources automatically. The prototype beam line is scheduled to begin operation in the fall of 1978 and all four production beam lines on TFTR in 1982.« less

Ion source and injection line for high intensity medical cyclotron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jia, XianLu, E-mail: jiaxl@ciae.ac.cn; Guan, Fengping; Yao, Hongjuan

2014-02-15

A 14 MeV high intensity compact cyclotron, CYCIAE-14, was built at China Institute of Atomic Energy (CIAE). An injection system based on the external H− ion source was used on CYCIAE-14 so as to provide high intensity beam, while most positron emission tomography cyclotrons adopt internal ion source. A beam intensity of 100 μA/14 MeV was extracted from the cyclotron with a small multi-cusp H− ion source (CIAE-CH-I type) and a short injection line, which the H− ion source of 3 mA/25 keV H− beam with emittance of 0.3π mm mrad and the injection line of with only 1.2 m from themore » extraction of ion source to the medial plane of the cyclotron. To increase the extracted beam intensity of the cyclotron, a new ion source (CIAE-CH-II type) of 9.1 mA was used, with maximum of 500 μA was achieved from the cyclotron. The design and test results of the ion source and injection line optimized for high intensity acceleration will be given in this paper.« less

StreaMorph: A Case for Synthesizing Energy-Efficient Adaptive Programs Using High-Level Abstractions

DTIC Science & Technology

2013-08-12

technique when switching from using eight cores to one core. 1. Introduction Real - time streaming of media data is growing in popularity. This includes...both capture and processing of real - time video and audio, and delivery of video and audio from servers; recent usage number shows over 800 million...source of data, when that source is a real - time source, and it is generally not necessary to get ahead of the sink. Even with real - time sources and sinks

Energy production from biosolids: A cattle feedlot demonstration system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fedler, C.B.; Parker, N.C.

1996-12-31

About 5 million head of cattle are produced annually from about 200 feedlots in the Texas High Plains with about 3.5 million head standing. Annually, the 3.5 million head of cattle produce about 28 millions metric tons of were manure (88% water). If anaerobically digested, the manure would yield about 1.4 million m{sup 3} of biogas, or about 4.4 million kWh daily. With cogeneration and nutrient recovery, the sum of the revenue sources in over $500 million annually and does no include the value of water or other byproducts such as fish and plants that could be produced from anmore » integrated system. A demonstration unit to treat the waste from a 1000-head cattle and a 280 sow farrow-to-finish swine operation is constructed. This system employs a 6 m deep anaerobic pit for production and capture of biogas integrated with a facultative pond, a shallow pond for production of aquatic plants, and a pond for production of fish or other aquatic species. The resulting related agribusinesses would not only produce additional revenues, but would also produce energy, improve the environment though extraction of nitrogen compounds, capture of gaseous emissions, reduction of odor, and creation of wildlife habitat in consturcted wetlants.« less

Effect through inhalation on human health of PM1 bound polycyclic aromatic hydrocarbons collected from foggy days in northern part of India.

PubMed

Singh, Dharmendra Kumar; Gupta, Tarun

2016-04-05

We investigated the health risk from 16 polycyclic aromatic hydrocarbons (PAHs) adsorbed on submicron particles and also reported their concentrations, spatial distribution and possible sources during foggy days at Kanpur. Twenty-four urban foggy day's samples gathered from Kanpur, an urban center in North India and most densely populated city in the Indo-Gangetic plain of India, were examined for 16 PAHs (2-6 rings).The mean concentration of PM1 was found to be 160.16±37.70μg/m(3). ∑16PAHs concentrations were 529.17ng/m(3) with a mean of 33.07ng/m(3). The compounds of higher molecular weight (4-6 rings) added to 70.67% of ∑PAHs mass concentration in the foggy day's samples. The results of source identification by using principle component analysis (PCA) and diagnostic ratios proposed that the primary sources of PAHs were vehicular emission (primarily driven by diesel fuel) and coal combustion and the secondary source. Exposure to total PAHs in the ambient air resulted in, 95% probability total Incremental Lifetime Cancer Risk (TILCR) 3.57×10(-5) for adults and 2.08×10(-5) for children or (∼35 cancer case per million in adults and ∼20 cancer case per million in children) due to inhalation in terms of ILCR were higher than the baseline value of acceptable risk (one cancer case per million people) suggesting moderate health risk to resident human population. Copyright © 2015 Elsevier B.V. All rights reserved.

40 CFR 98.80 - Definition of the source category.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Cement Production § 98.80 Definition of the source category. The cement production source category consists of each kiln and each in-line kiln/raw mill at any portland cement manufacturing facility including alkali bypasses, and includes kilns and in-line kiln/raw...

40 CFR 98.80 - Definition of the source category.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Cement Production § 98.80 Definition of the source category. The cement production source category consists of each kiln and each in-line kiln/raw mill at any portland cement manufacturing facility including alkali bypasses, and includes kilns and in-line kiln/raw...

40 CFR 98.80 - Definition of the source category.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Cement Production § 98.80 Definition of the source category. The cement production source category consists of each kiln and each in-line kiln/raw mill at any portland cement manufacturing facility including alkali bypasses, and includes kilns and in-line kiln/raw...

QSL Squasher: A Fast Quasi-separatrix Layer Map Calculator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tassev, Svetlin; Savcheva, Antonia, E-mail: svetlin.tassev@cfa.harvard.edu

Quasi-Separatrix Layers (QSLs) are a useful proxy for the locations where current sheets can develop in the solar corona, and give valuable information about the connectivity in complicated magnetic field configurations. However, calculating QSL maps, even for two-dimensional slices through three-dimensional models of coronal magnetic fields, is a non-trivial task, as it usually involves tracing out millions of magnetic field lines with immense precision. Thus, extending QSL calculations to three dimensions has rarely been done until now. In order to address this challenge, we present QSL Squasher—a public, open-source code, which is optimized for calculating QSL maps in both twomore » and three dimensions on graphics processing units. The code achieves large processing speeds for three reasons, each of which results in an order-of-magnitude speed-up. (1) The code is parallelized using OpenCL. (2) The precision requirements for the QSL calculation are drastically reduced by using perturbation theory. (3) A new boundary detection criterion between quasi-connectivity domains is used, which quickly identifies possible QSL locations that need to be finely sampled by the code. That boundary detection criterion relies on finding the locations of abrupt field-line length changes, which we do by introducing a new Field-line Length Edge (FLEDGE) map. We find FLEDGE maps useful on their own as a quick-and-dirty substitute for QSL maps. QSL Squasher allows construction of high-resolution 3D FLEDGE maps in a matter of minutes, which is two orders of magnitude faster than calculating the corresponding 3D QSL maps. We include a sample of calculations done using QSL Squasher to demonstrate its capabilities as a QSL calculator, as well as to compare QSL and FLEDGE maps.« less

The Virginia Beach shallow ground-water study

USGS Publications Warehouse

Johnson, Henry M.

1999-01-01

IntroductionVirginia Beach is a rapidly growing city of more than 425,000 people. Sources of fresh water within the city, however, are limited. Prior to 1998, the Virginia Beach Public Utilities Department met the city's water needs by purchasing treated drinking water from the City of Norfolk. Because Norfolk had to meet its own requirements, the amount of water available to Virginia Beach was limited to about 30 million gallons per day (mgd) and even less during droughts. This water supply was supplemented with ground water from city-owned, community, and private wells. In many parts of the city, however, ground water cannot be used because of high concentrations of chloride, iron, and (or) sulfur, which give the water an unpleasant taste.In early 1998, a pipeline came on-line that can carry up to 45 mgd of water from Lake Gaston to Virginia Beach. The Gaston pipeline has alleviated concerns about water supply and quality for most residents living north of the "Green Line." These residents primarily use ground water only for small-scale domestic activities such as watering lawns, filling ponds and pools, and washing cars. City water and sewer services have been extended beyond the Green Line into the "Transition Area." Residents and businesses south of the Transition Area, however, continue to rely on ground water to meet most of their needs for potable and non-potable water. To help assure a continued, reliable supply of ground water, the U.S. Geological Survey (USGS), in cooperation with the City of Virginia Beach Public Utilities Department, has begun an assessment of the shallow ground-water resources underlying the City of Virginia Beach.

Constraining parameters of white-dwarf binaries using gravitational-wave and electromagnetic observations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shah, Sweta; Nelemans, Gijs, E-mail: s.shah@astro.ru.nl

The space-based gravitational wave (GW) detector, evolved Laser Interferometer Space Antenna (eLISA) is expected to observe millions of compact Galactic binaries that populate our Milky Way. GW measurements obtained from the eLISA detector are in many cases complimentary to possible electromagnetic (EM) data. In our previous papers, we have shown that the EM data can significantly enhance our knowledge of the astrophysically relevant GW parameters of Galactic binaries, such as the amplitude and inclination. This is possible due to the presence of some strong correlations between GW parameters that are measurable by both EM and GW observations, for example, themore » inclination and sky position. In this paper, we quantify the constraints in the physical parameters of the white-dwarf binaries, i.e., the individual masses, chirp mass, and the distance to the source that can be obtained by combining the full set of EM measurements such as the inclination, radial velocities, distances, and/or individual masses with the GW measurements. We find the following 2σ fractional uncertainties in the parameters of interest. The EM observations of distance constrain the chirp mass to ∼15%-25%, whereas EM data of a single-lined spectroscopic binary constrain the secondary mass and the distance with factors of two to ∼40%. The single-line spectroscopic data complemented with distance constrains the secondary mass to ∼25%-30%. Finally, EM data on double-lined spectroscopic binary constrain the distance to ∼30%. All of these constraints depend on the inclination and the signal strength of the binary systems. We also find that the EM information on distance and/or the radial velocity are the most useful in improving the estimate of the secondary mass, inclination, and/or distance.« less

Train-induced field vibration measurements of ground and over-track buildings.

PubMed

Zou, Chao; Wang, Yimin; Moore, James A; Sanayei, Masoud

2017-01-01

Transit-oriented development, such as metro depot and over-track building complexes, has expanded rapidly over the last 5years in China. Over-track building construction has the advantage of comprehensive utilization of land resources, ease of commuting to work, and provide funds for subway construction. But the high frequency of subway operations into and out of the depots can generate excessive vibrations that transmit into the over track buildings, radiate noise within the buildings, hamper the operation of vibration sensitive equipment, and adversely affect the living quality of the building occupants. Field measurements of vibration during subway operations were conducted at Shenzhen, China, a city of 10.62 million people in southern China. Considering the metro depot train testing line and throat area train lines were the main vibration sources, vibration data were captured in five measurement setups. The train-induced vibrations were obtained and compared with limitation of FTA criteria. The structure-radiated noise was calculated using measured vibration levels. The vertical vibration energy directly passed through the columns on both sides of track into the platform, amplifying vibration on the platform by up to 6dB greater than ground levels at testing line area. Vibration amplification around the natural frequency in the vertical direction of over-track building made the peak values of indoor floor vibration about 16dB greater than outdoor platform vibration. We recommend to carefully examining design of new over-track buildings within 40m on the platform over the throat area to avoid excessive vertical vibrations and noise. For both buildings, the measured vertical vibrations were less than the FTA limit. However, it is demonstrated that the traffic-induced high-frequency noise has the potential to annoy occupants on the upper floors. Copyright © 2016 Elsevier B.V. All rights reserved.

QSL Squasher: A Fast Quasi-separatrix Layer Map Calculator

NASA Astrophysics Data System (ADS)

Tassev, Svetlin; Savcheva, Antonia

2017-05-01

Quasi-Separatrix Layers (QSLs) are a useful proxy for the locations where current sheets can develop in the solar corona, and give valuable information about the connectivity in complicated magnetic field configurations. However, calculating QSL maps, even for two-dimensional slices through three-dimensional models of coronal magnetic fields, is a non-trivial task, as it usually involves tracing out millions of magnetic field lines with immense precision. Thus, extending QSL calculations to three dimensions has rarely been done until now. In order to address this challenge, we present QSL Squasher—a public, open-source code, which is optimized for calculating QSL maps in both two and three dimensions on graphics processing units. The code achieves large processing speeds for three reasons, each of which results in an order-of-magnitude speed-up. (1) The code is parallelized using OpenCL. (2) The precision requirements for the QSL calculation are drastically reduced by using perturbation theory. (3) A new boundary detection criterion between quasi-connectivity domains is used, which quickly identifies possible QSL locations that need to be finely sampled by the code. That boundary detection criterion relies on finding the locations of abrupt field-line length changes, which we do by introducing a new Field-line Length Edge (FLEDGE) map. We find FLEDGE maps useful on their own as a quick-and-dirty substitute for QSL maps. QSL Squasher allows construction of high-resolution 3D FLEDGE maps in a matter of minutes, which is two orders of magnitude faster than calculating the corresponding 3D QSL maps. We include a sample of calculations done using QSL Squasher to demonstrate its capabilities as a QSL calculator, as well as to compare QSL and FLEDGE maps.

Landquake dynamics inferred from seismic source inversion: Greenland and Sichuan events of 2017

NASA Astrophysics Data System (ADS)

Chao, W. A.

2017-12-01

In June 2017 two catastrophic landquake events occurred in Greenland and Sichuan. The Greenland event leads to tsunami hazard in the small town of Nuugaarsiaq. A landquake in Sichuan hit the town, which resulted in over 100 death. Both two events generated the strong seismic signals recorded by the real-time global seismic network. I adopt an inversion algorithm to derive the landquake force time history (LFH) using the long-period waveforms, and the landslide volume ( 76 million m3) can be rapidly estimated, facilitating the tsunami-wave modeling for early warning purpose. Based on an integrated approach involving tsunami forward simulation and seismic waveform inversion, this study has significant implications to issuing actionable warnings before hazardous tsunami waves strike populated areas. Two single-forces (SFs) mechanism (two block model) yields the best explanation for Sichuan event, which demonstrates that secondary event (seismic inferred volume: 8.2 million m3) may be mobilized by collapse-mass hitting from initial rock avalanches ( 5.8 million m3), likely causing a catastrophic disaster. The later source with a force magnitude of 0.9967×1011 N occurred 70 seconds after first mass-movement occurrence. In contrast, first event has the smaller force magnitude of 0.8116×1011 N. In conclusion, seismically inferred physical parameters will substantially contribute to improving our understanding of landquake source mechanisms and mitigating similar hazards in other parts of the world.

Exposure to Electronic Cigarette Advertising Among Middle and High School Students - United States, 2014-2016.

PubMed

Marynak, Kristy; Gentzke, Andrea; Wang, Teresa W; Neff, Linda; King, Brian A

2018-03-16

Electronic cigarettes (e-cigarettes) are the most commonly used tobacco product among U.S. middle and high school students (1). Exposure to e-cigarette advertisements is associated with higher odds of current e-cigarette use among middle and high school students (2-4). To assess patterns of self-reported exposure to four e-cigarette advertising sources (retail stores, the Internet, television, and newspapers and magazines), CDC analyzed data from the 2014, 2015, and 2016 National Youth Tobacco Surveys (NYTSs). Overall, exposure to e-cigarette advertising from at least one source increased each year during 2014-2016 (2014: 68.9%, 18.3 million; 2015: 73.0%, 19.2 million; 2016: 78.2%, 20.5 million). In 2016, exposure was highest for retail stores (68.0%), followed by the Internet (40.6%), television (37.7%), and newspapers and magazines (23.9%). During 2014-2016, youth exposure to e-cigarette advertising increased for retail stores (54.8% to 68.0%), decreased for newspapers and magazines (30.4% to 23.9%), and did not significantly change for the Internet or television. A comprehensive strategy to prevent and reduce youth use of e-cigarettes and other tobacco products includes efforts to reduce youth exposure to e-cigarette advertising from a range of sources, including retail stores, television, the Internet, and print media such as newspapers and magazines (5).

Estimation of the Change in Freshwater Volume in the North Coast Limestone Upper Aquifer of Puerto Rico in the Rio Grande de Manati-Rio de la Plata Area between 1960 and 1990 and Implications on Public-Supply Water Availability

USGS Publications Warehouse

Gómez-Gómez, Fernando

2008-01-01

Ground water in the upper aquifer of the North Coast Limestone aquifer system historically has been the principal source of public-supply and self-supplied industrial water use in north-central Puerto Rico. Development of the aquifer for these two major water-use categories began in about 1930; however, withdrawals did not become an important water-supply source for sustaining local development until the 1960s. Ground-water withdrawals averaged about 6 million gallons per day from 1948 to the mid-1960s and peaked at about 33 million gallons per day in the 1980s. Withdrawals have since declined, averaging about 11.5 million gallons per day in 2002. Aquifer contamination by industrial chemical spills and by nitrates from agricultural and domestic sources initially reduced pumpage for public-supply use within localized areas, leading eventually to increased withdrawals at unaffected well fields. The long-term effect of unconstrained ground-water withdrawals has been a regional thinning of the freshwater lens in an area encompassing 50,600 acres between the Rio Grande de Manati and Rio de la Plata, generally north of latitude 18?25?. The effects of aquifer overdraft have been documented in the regional thinning of the freshwater lens, with an increase in dissolved-solids concentration in ground-water wells. Dissolved-solids concentration in public-supply wells were generally between 250 and 350 milligrams per liter during the 1960s, but increased to greater than 500 milligrams per liter in virtually all of the wells by 2000. Depletion of fresh ground water was estimated at 282,000 acre-feet: 103,000 acre-feet in the Rio Grande de Manati to Rio Cibuco area between 1960 and 1995, and 179,000 acre-feet in the Rio Cibuco to Rio de la Plata area between 1960 and 1992. Thus, aquifer freshwater volume depletion below mean sea level datum may have contributed as much as 38 percent (7.5 million gallons per day) of the 20-million gallons per day average withdrawal rate during the stated time periods. The calculated depletion of aquifer freshwater volume is equivalent to an average long-term rate of 8,400 acre-feet per year. Aquifer withdrawals can be anticipated to decline to about 10 million gallons per day by 2010 at the projected trend of well closures. The lost supply would have to be compensated from surface-water sources because the part of the North Coast Limestone aquifer system south of latitude 18?25?, although less vulnerable to saline-water encroachment, is not as productive.

Whole genome SNP discovery and analysis of genetic diversity in Turkey (Meleagris gallopavo)

PubMed Central

2012-01-01

Background The turkey (Meleagris gallopavo) is an important agricultural species and the second largest contributor to the world’s poultry meat production. Genetic improvement is attributed largely to selective breeding programs that rely on highly heritable phenotypic traits, such as body size and breast muscle development. Commercial breeding with small effective population sizes and epistasis can result in loss of genetic diversity, which in turn can lead to reduced individual fitness and reduced response to selection. The presence of genomic diversity in domestic livestock species therefore, is of great importance and a prerequisite for rapid and accurate genetic improvement of selected breeds in various environments, as well as to facilitate rapid adaptation to potential changes in breeding goals. Genomic selection requires a large number of genetic markers such as e.g. single nucleotide polymorphisms (SNPs) the most abundant source of genetic variation within the genome. Results Alignment of next generation sequencing data of 32 individual turkeys from different populations was used for the discovery of 5.49 million SNPs, which subsequently were used for the analysis of genetic diversity among the different populations. All of the commercial lines branched from a single node relative to the heritage varieties and the South Mexican turkey population. Heterozygosity of all individuals from the different turkey populations ranged from 0.17-2.73 SNPs/Kb, while heterozygosity of populations ranged from 0.73-1.64 SNPs/Kb. The average frequency of heterozygous SNPs in individual turkeys was 1.07 SNPs/Kb. Five genomic regions with very low nucleotide variation were identified in domestic turkeys that showed state of fixation towards alleles different than wild alleles. Conclusion The turkey genome is much less diverse with a relatively low frequency of heterozygous SNPs as compared to other livestock species like chicken and pig. The whole genome SNP discovery study in turkey resulted in the detection of 5.49 million putative SNPs compared to the reference genome. All commercial lines appear to share a common origin. Presence of different alleles/haplotypes in the SM population highlights that specific haplotypes have been selected in the modern domesticated turkey. PMID:22891612

Optimizing antiretroviral product selection: a sample approach to improving patient outcomes, saving money, and scaling-up health services in developing countries.

PubMed

Amole, Carolyn D; Brisebois, Catherine; Essajee, Shaffiq; Koehler, Erin; Levin, Andrew D; Moore, Meredith C; Brown Ripin, David H; Sickler, Joanna J; Singh, Inder R

2011-08-01

Over the last decade, increased funding to support HIV treatment programs has enabled millions of new patients in developing countries to access the medications they need. Today, although demand for antiretrovirals continues to grow, the financial crisis has severely constrained funding leaving countries with difficult choices on program prioritization. Product optimization is one solution countries can pursue to continue to improve patient care while also uncovering savings that can be used for further scale up or other health system needs. Program managers can make procurement decisions that actually reduce program costs by considering additional factors beyond World Health Organization guidelines when making procurement decisions. These include in-country product availability, convenience, price, and logistics such as supply chain implications and laboratory testing requirements. Three immediate product selection opportunities in the HIV space include using boosted atazanavir in place of lopinovir for second-line therapy, lamivudine instead of emtricitabine in both first-line and second-line therapy, and tenofovir + lamivudine over abacavir + didanosine in second-line therapy. If these 3 opportunities were broadly implemented in sub-Saharan Africa and India today, approximately $300 million of savings would be realized over the next 5 years, enabling hundreds of thousands of additional patients to be treated. Although the discussion herein is specific to antriretrovirals, the principles of product selection are generalizable to diseases with multiple treatment options and fungible commodity procurement. Identifying and implementing approaches to overcome health system inefficiencies will help sustain and may expand quality care in resource-limited settings.

False Color Aurora

NASA Image and Video Library

1997-09-23

Data from NASA's Galileo spacecraft were used to produce this false-color composite of Jupiter's northern aurora on the night side of the planet. The height of the aurora, the thickness of the auroral arc, and the small-scale structure are revealed for the first time. Images in Galileo's red, green, and clear filters are displayed in red, green, and blue respectively. The smallest resolved features are tens of kilometers in size, which is a ten-fold improvement over Hubble Space Telescope images and a hundred-fold improvement over ground-based images. The glow is caused by electrically charged particles impinging on the atmosphere from above. The particles travel along Jupiter's magnetic field lines, which are nearly vertical at this latitude. The auroral arc marks the boundary between the "closed" field lines that are attached to the planet at both ends and the "open" field lines that extend out into interplanetary space. At the boundary the particles have been accelerated over the greatest distances, and the glow is especially intense. The latitude-longitude lines refer to altitudes where the pressure is 1 bar. The image shows that the auroral emissions originate about 500 kilometers (about 310 miles) above this surface. The colored background is light scattered from Jupiter's bright crescent, which is out of view to the right. North is at the top. The images are centered at 57 degrees north and 184 degrees west and were taken on April 2, 1997 at a range of 1.7 million kilometers (1.05 million miles) by Galileo's Solid State Imaging (SSI) system. http://photojournal.jpl.nasa.gov/catalog/PIA00603

Material flows of mobile phones and accessories in Nigeria: Environmental implications and sound end-of-life management options

DOE Office of Scientific and Technical Information (OSTI.GOV)

Osibanjo, Oladele; Nnorom, Innocent Chidi

Presently, Nigeria is one of the fastest growing Telecom markets in the world. The country's teledensity increased from a mere 0.4 in 1999 to 10 in 2005 following the liberalization of the Telecom sector in 2001. More than 25 million new digital mobile lines have been connected by June 2006. Large quantities of mobile phones and accessories including secondhand and remanufactured products are being imported to meet the pent-up demand. This improvement in mobile telecom services resulted in the preference of mobile telecom services to fixed lines. Consequently, the contribution of fixed lines decreased from about 95% in year 2000more » to less than 10% in March 2005. This phenomenal progress in information technology has resulted in the generation of large quantities of electronic waste (e-waste) in the country. Abandoned fixed line telephone sets estimated at 120,000 units are either disposed or stockpiled. Increasing quantities of waste mobile phones estimated at 8 million units by 2007, and accessories will be generated. With no material recovery facility for e-waste and/or appropriate solid waste management infrastructure in place, these waste materials end up in open dumps and unlined landfills. These practices create the potential for the release of toxic metals and halocarbons from batteries, printed wiring boards, liquid crystal display and plastic housing units. This paper presents an overview of the developments in the Nigerian Telecom sector, the material in-flow of mobile phones, and the implications of the management practices for wastes from the Telecom sector in the country.« less

First Detections of the [N II] 122 micron Line at High Redshift: Demonstrating the Utility of the Line for Studying Galaxies in the Early Universe

NASA Technical Reports Server (NTRS)

Ferkinhoff, Carl; Brisbin, Drew; Nikola, Thomas; Parshley, Stephen C.; Stacey, Gordon J.; Phillips, Thomas G.; Falgarone, Edith; Benford, Dominic J.; Staguhn, Johannes G.; Tucker, Carol E.

2011-01-01

We report the first detections of the [N II] 122 micron line from a high-redshift galaxy. The line was strongly (>6(sigma)) detected from SMMJ02399-0136, and H1413 + 117 (the Cloverleaf QSO) using the Redshift (zeta) and Early Universe Spectrometer on the Caltech Submillimeter Observatory. The lines from both sources are quite bright with line to far-infrared (FIR) continuum luminosity ratios that are approx.7.0 x 10(exp -4) (Cloverleaf) and 2.1 x 10(exo -3) (SMMJ02399). With ratios 2-10 times larger than the average value for nearby galaxies, neither source exhibits the line to continuum deficits seen in nearby sources. The line strengths also indicate large ionized gas fractions, approx.8%-17% of the molecUlar gas mass. The [O III]/[N II] line ratio is very sensitive to the effective temperature of ionizing stars and the ionization parameter for emission arising in the narrow-line region (NLR) of an active galactic nucleus (AGN). Using Our previous detection of the [O III] 88 micron line, the [O III]/[N II]line ratio for SMMJ02399-0136 indicates that the dominant source of the line emission is either stellar H II regions ionized by O9.5 stars, or the NLR of the AGN with ionization parameter log(U) = -3.3 to -4.0. A composite system, where 30%-50% of the FIR lines arise in the NLR also matches the data. The Cloverleaf is best modeled by a superposition of approx.200 M82-like starbursts accounting for all of the FIR emission and 43% of the [N II]line. The remainder may come from the NLR. This war!< demonstrates the utility of the [N II] and [O III] lines in constraining properties of the ionized medium.

Human Development, Human Evolution.

ERIC Educational Resources Information Center

Smillie, David

One of the truly remarkable events in human evolution is the unprecedented increase in the size of the brain of "Homo" over a brief span of 2 million years. It would appear that some significant selective pressure or opportunity presented itself to this branch of the hominid line and caused a rapid increase in the brain, introducing a…

75 FR 51455 - Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

... loops,\\1\\ construct one new compressor station, add compression at two existing compressor stations, and perform other modifications to five compressor stations. The MSEP would provide about 451 million standard... Mobile Bay Lateral, down to existing Compressor Station 85. According to Transco, its project would...

17 CFR Appendix B to Part 420 - Sample Large Position Report

Code of Federal Regulations, 2013 CFR

2013-04-01

... $ Memorandum 2: Report the gross par amount of fails to deliver. Included in the calculation of line item 3... millions at par value as of trade date] Security Being Reported Date For Which Information is Being... Principal Components of the Specific Security $ Total Net Trading Position $ 2. Gross Financing Position...

17 CFR Appendix B to Part 420 - Sample Large Position Report

Code of Federal Regulations, 2012 CFR

2012-04-01

... $ Memorandum 2: Report the gross par amount of fails to deliver. Included in the calculation of line item 3... millions at par value as of trade date] Security Being Reported Date For Which Information is Being... Principal Components of the Specific Security $ Total Net Trading Position $ 2. Gross Financing Position...

17 CFR Appendix B to Part 420 - Sample Large Position Report

Code of Federal Regulations, 2011 CFR

2011-04-01

... $ Memorandum 2: Report the gross par amount of fails to deliver. Included in the calculation of line item 3... millions at par value as of trade date] Security Being Reported Date For Which Information is Being... Principal Components of the Specific Security $ Total Net Trading Position $ 2. Gross Financing Position...

China’s Assistance and Government-Sponsored Investment Activities in Africa, Latin America, and Southeast Asia

DTIC Science & Technology

2009-11-25

line.55 In January 2008, the Indonesian state electricity company signed an agreement with China’s Eximbank to borrow $615 million to build coal -fired...aid in the construction of infrastructure and educational facilities in exchange for rights over copper and cobalt deposits .37 Examples of PRC

Poverty Matters: The Cost of Child Poverty in America.

ERIC Educational Resources Information Center

Sherman, Arloc

The poverty affecting 14.5 million U.S. children living below the poverty line poses long-term effects, including risks to health, educational achievement, family stability, and employment prospects. This report provides compelling evidence of the substantial costs of poverty among children to our nation's economic well-being, and shows that…

On the Front Line

ERIC Educational Resources Information Center

Ruffins, Paul

2011-01-01

Physician assistants take on primary care duties that were once the exclusive domain of physicians. According to Kevin Lohenry, director of the Primary Care Physician Assistant Program at the University of Southern California, there are either 90,000 or 30 million reasons why someone might see a physician assistant rather than a physician. The 30…

A new rainbow trout (Oncorhynchus mykiss) reference genome assembly

USDA-ARS?s Scientific Manuscript database

In an effort to improve the rainbow trout reference genome assembly, we have re-sequenced the doubled-haploid Swanson line using the longest available reads from the Illumina technology. Overall we generated over 510 million 260nt paired-end shotgun reads, and 1 billion 160nt mate-pair reads from f...

Wind Energy Systems.

ERIC Educational Resources Information Center

Conservation and Renewable Energy Inquiry and Referral Service (DOE), Silver Spring, MD.

During the 1920s and 1930s, millions of wind energy systems were used on farms and other locations far from utility lines. However, with passage of the Rural Electrification Act in 1939, cheap electricity was brought to rural areas. After that, the use of wind machines dramatically declined. Recently, the rapid rise in fuel prices has led to a…

Report on Progress toward Security and Stability in Afghanistan

DTIC Science & Technology

2009-10-01

teams from Germany, two teams from Poland , two teams from the Netherlands, and one team from Canada. The Mol and CSTC-A are implementing a modified...Development Bank sponsored construction of a rail line from the Uzbek border to Mazer e Sharif. Kazakhstan has also provided $50 million to educate more than

Absolute quantification of the host-to-parasite DNA ratio in theileria parva-infected lymphocyte cell lines

USDA-ARS?s Scientific Manuscript database

Theileria parva is a tick-transmitted intracellular apicomplexan pathogen of cattle in sub-Saharan Africa that causes East Coast fever (ECF). ECF is an acute fatal disease that kills over one million cattle annually, imposing a tremendous burden on African small-holder cattle farmers. The pathology ...

Craters 'Twixt Day and Night

NASA Image and Video Library

2004-12-20

Three sizeable impact craters, including one with a marked central peak, lie along the line that divides day and night on the Saturnian moon, Dione (dee-OH-nee), which is 1,118 kilometers, or 695 miles across. The low angle of the Sun along the terminator, as this dividing line is called, brings details like these craters into sharp relief. This view shows principally the leading hemisphere of Dione. Some of this moon's bright, wispy streaks can be seen curling around its eastern limb. Cassini imaged the wispy terrain at high resolution during its first Dione flyby on Dec. 14, 2004. This image was taken in visible light with the Cassini spacecraft narrow angle camera on Nov. 1, 2004, at a distance of 2.4 million kilometers (1.5 million miles) from Dione and at a Sun-Dione-spacecraft, or phase, angle of 106 degrees. North is up. The image scale is 14 kilometers (8.7 miles) per pixel. The image has been magnified by a factor of two and contrast-enhanced to aid visibility of surface features. http://photojournal.jpl.nasa.gov/catalog/PIA06542

The Hidden Poor: Over Three-Quarters of a Million Older Californians Overlooked by Official Poverty Line.

PubMed

Padilla-Frausto, Imelda D; Wallace, Steven P

2015-08-01

More than three-quarters of a million (772,000) older Californians are among the "hidden poor"--older adults with incomes above the federal poverty line (FPL) but below a minimally decent standard of living as determined by the Elder Economic Security Standard™ Index (Elder Index) in 2011. This policy brief uses the most recent Elder Index calculations to document the wide discrepancy that exists between the FPL and the Elder Index. This study finds that the FPL significantly underestimates the number of economically insecure older adults who are unable to make ends meet. Yet, because many public assistance programs are aligned with the FPL, potentially hundreds of thousands of economically insecure older Californians are denied aid. The highest rates of the hidden poor among older adults are found among renters, Latinos, women, those who are raising grandchildren, and people in the oldest age groups. Raising the income and asset eligibility requirement thresholds for social support programs such as Supplemental Security Income (SSI), housing, health care, and food assistance would help California's older hidden poor make ends meet.

Chapter 5: Geologic Assessment of Undiscovered Petroleum Resources in the Waltman Shale Total Petroleum System,Wind River Basin Province, Wyoming

USGS Publications Warehouse

Roberts, Steve B.; Roberts, Laura N.R.; Cook, Troy

2007-01-01

The Waltman Shale Total Petroleum System encompasses about 3,400 square miles in the Wind River Basin Province, Wyoming, and includes accumulations of oil and associated gas that were generated and expelled from oil-prone, lacustrine shale source rocks in the Waltman Shale Member of the Paleocene Fort Union Formation. Much of the petroleum migrated and accumulated in marginal lacustrine (deltaic) and fluvial sandstone reservoirs in the Shotgun Member of the Fort Union, which overlies and intertongues with the Waltman Shale Member. Additional petroleum accumulations derived from Waltman source rocks are present in fluvial deposits in the Eocene Wind River Formation overlying the Shotgun Member, and also might be present within fan-delta deposits included in the Waltman Shale Member, and in fluvial sandstone reservoirs in the uppermost part of the lower member of the Fort Union Formation immediately underlying the Waltman. To date, cumulative production from 53 wells producing Waltman-sourced petroleum exceeds 2.8 million barrels of oil and 5.8 billion cubic feet of gas. Productive horizons range from about 1,770 feet to 5,800 feet in depth, and average about 3,400 to 3,500 feet in depth. Formations in the Waltman Shale Total Petroleum System (Fort Union and Wind River Formations) reflect synorogenic deposition closely related to Laramide structural development of the Wind River Basin. In much of the basin, the Fort Union Formation is divided into three members (ascending order): the lower unnamed member, the Waltman Shale Member, and the Shotgun Member. These members record the transition from deposition in dominantly fluvial, floodplain, and mire environments in the early Paleocene (lower member) to a depositional setting characterized by substantial lacustrine development (Waltman Shale Member) and contemporaneous fluvial, and marginal lacustrine (deltaic) deposition (Shotgun Member) during the middle and late Paleocene. Waltman Shale Member source rocks have total organic carbon values ranging from 0.93 to 6.21 weight percent, averaging about 2.71 weight percent. The hydrocarbon generative potential of the source rocks typically exceeds 2.5 milligrams of hydrocarbon per gram of rock and numerous samples had generative potentials exceeding 6.0 milligrams of hydrocarbon per gram of rock. Waltman source rocks are oil prone, and contain a mix of Type-II and Type-III kerogen, indicating organic input from a mix of algal and terrestrial plant matter, or a mix of algal and reworked or recycled material. Thermal maturity at the base of the Waltman Shale Member ranges from a vitrinite reflectance value of less than 0.60 percent along the south basin margin to projected values exceeding 1.10 percent in the deep basin west of Madden anticline. Burial history reconstructions for three wells in the northern part of the Wind River Basin indicate that the Waltman Shale Member was well within the oil window (Ro equal to or greater than 0.65 percent) by the time of maximum burial about 15 million years ago; maximum burial depths exceeded 10,000 feet. Onset of oil generation calculated for the base of the Waltman Shale member took place from about 49 million years ago to about 20 million years ago. Peak oil generation occurred from about 31 million years ago to 26 million years ago in the deep basin west of Madden anticline. Two assessment units were defined in the Waltman Shale Total Petroleum System: the Upper Fort Union Sandstones Conventional Oil and Gas Assessment Unit (50350301) and the Waltman Fractured Shale Continuous Oil Assessment Unit (50350361). The conventional assessment unit primarily relates to the potential for undiscovered petroleum accumulations that are derived from source rocks in the Waltman Shale Member and trapped within sandstone reservoirs in the Shotgun Member (Fort Union Formation) and in the lower part of the overlying Wind River Formation. The potential for Waltman-sourced oil accumulations in fan-delta depos

Localization of source with unknown amplitude using IPMC sensor arrays

NASA Astrophysics Data System (ADS)

Abdulsadda, Ahmad T.; Zhang, Feitian; Tan, Xiaobo

2011-04-01

The lateral line system, consisting of arrays of neuromasts functioning as flow sensors, is an important sensory organ for fish that enables them to detect predators, locate preys, perform rheotaxis, and coordinate schooling. Creating artificial lateral line systems is of significant interest since it will provide a new sensing mechanism for control and coordination of underwater robots and vehicles. In this paper we propose recursive algorithms for localizing a vibrating sphere, also known as a dipole source, based on measurements from an array of flow sensors. A dipole source is frequently used in the study of biological lateral lines, as a surrogate for underwater motion sources such as a flapping fish fin. We first formulate a nonlinear estimation problem based on an analytical model for the dipole-generated flow field. Two algorithms are presented to estimate both the source location and the vibration amplitude, one based on the least squares method and the other based on the Newton-Raphson method. Simulation results show that both methods deliver comparable performance in source localization. A prototype of artificial lateral line system comprising four ionic polymer-metal composite (IPMC) sensors is built, and experimental results are further presented to demonstrate the effectiveness of IPMC lateral line systems and the proposed estimation algorithms.

High temperature ion source for an on-line isotope separator

DOEpatents

Mlekodaj, Ronald L.

1979-01-01

A reduced size ion source for on-line use with a cyclotron heavy-ion beam is provided. A sixfold reduction in source volume while operating with similar input power levels results in a 2000.degree. C. operating temperature. A combined target/window normally provides the reaction products for ionization while isolating the ion source plasma from the cyclotron beam line vacuum. A graphite felt catcher stops the recoiling reaction products and releases them into the plasma through diffusion and evaporation. Other target arrangements are also possible. A twenty-four hour lifetime of unattended operation is achieved, and a wider range of elements can be studied than was heretofore possible.

Extended Source/Galaxy All Sky 1

NASA Image and Video Library

2003-03-27

This panoramic view of the entire sky reveals the distribution of galaxies beyond our Milky Way galaxy, which astronomers call extended sources, as observed by Two Micron All-Sky Survey. The image is constructed from a database of over 1.6 million galaxies listed in the survey's Extended Source Catalog; more than half of the galaxies have never before been catalogued. The image is a representation of the relative brightnesses of these million-plus galaxies, all observed at a wavelength of 2.2 microns. The brightest and nearest galaxies are represented in blue, and the faintest, most distant ones are in red. This color scheme gives insights into the three dimensional large-scale structure of the nearby universe with the brightest, closest clusters and superclusters showing up as the blue and bluish-white features. The dark band in this image shows the area of the sky where our Milky Way galaxy blocks our view of distant objects, which, in this projection, lies predominantly along the edges of the image. http://photojournal.jpl.nasa.gov/catalog/PIA04252

'Between one and three million': towards the demographic reconstruction of a decade of Cambodian history (1970-79).

PubMed

Heuveline, P

1998-03-01

Estimates of mortality in Camabodia during the Khmer Rouge regime (1975-79) range from 20,000 deaths according to former Khmer Rouge sources, to over three million victims according to Vietnamese government sources. This paper uses an unusual data source - the 1992 electoral lists registered by the United Nations - to estimate the population size after the Khmer Rouge regime and the extent of "excess" mortality in the 1970s. These data also provide the first breakdown of population by single year of age, which allows analysis of the age structure of "excess" mortality and inference of the relative importance of violence as a cause of death in that period. The estimates derived here are more comparable with the higher estimates made in the past. In addition, the analysis of likely causes of death that could have generated the age pattern of "excess" mortality clearly shows a larger contribution of direct or violent mortality than has been previously recognized.

Estimated water use, by county, in North Carolina, 1990

USGS Publications Warehouse

Terziotti, Silvia; Schrader, Tony P.; Treece, M.W.

1994-01-01

Data on water use in North Carolina were compiled for 1990 as part of a cooperative agreement between the U.S. Geological Survey and the Division of Water Resources of the North Carolina Department of Environment, Health, and Natural Resources. Data were compiled from a number of Federal, State, and private sources for the offstream water-use categories of public supply, domestic, commercial, industrial, mining, livestock, irrigation, and thermoelectric-power generation. Data also were collected for instream use from hydroelectric facilities. Total estimated offstream water use in the State for 1990 was about 8,940 million gallons per day. About 95 percent of the water withdrawn was from surface-water sources. Thermoelectric-power generation accounted for about 81 percent of all withdrawals. Data for instream water use for hydroelectric-power generation also were compiled. This instream water use totaled about 66,900 million gallons per day. eAch water-use category is summarized in this report by county and source of water supply.

Creation of a national resource with linked genealogy and phenotypic data: the Veterans Genealogy Project.

PubMed

Cannon-Albright, Lisa A; Dintelman, Sue; Maness, Tim; Backus, Steve; Thomas, Alun; Meyer, Laurence J

2013-07-01

Creation of a genealogy of the United States and its ancestral populations is under way. When complete, this US genealogy will be record linked to the National Veteran's Health Administration medical data representing more than 8 million US veterans. Genealogical data are gathered from public sources, primarily the Internet. Record linking using data from relatives is accomplished to integrate multiple data sources and then to link genealogical data to the veteran's demographic data. This resource currently includes genealogy for more than 22 million individuals representing the Intermountain West and the East Coast. The demographic data for more than 40,000 veteran patients using Veterans Hospital Administration services in Utah and Massachusetts have already been record linked. The resource is only in its second year of creation and already represents the largest such combination of genealogy and medical data in the world. The data sources, the creation of the genealogy, record-linking methods and results, proposed genetic analyses, and future directions are discussed.

Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells.

PubMed

Lukhele, Sindiswa T; Motadi, Lesetja R

2016-09-01

Cervical cancer remains a global health related issue among females of Sub-Saharan Africa, with over half a million new cases reported each year. Different therapeutic regimens have been suggested in various regions of Africa, however, over a quarter of a million women die of cervical cancer, annually. This makes it the most lethal cancer amongst black women and calls for urgent therapeutic strategies. In this study we compare the anti-proliferative effects of crude extract of Cannabis sativa and its main compound cannabidiol on different cervical cancer cell lines. To achieve our aim, phytochemical screening, MTT assay, cell growth analysis, flow cytometry, morphology analysis, Western blot, caspase 3/7 assay, and ATP measurement assay were conducted. Results obtained indicate that both cannabidiol and Cannabis sativa extracts were able to halt cell proliferation in all cell lines at varying concentrations. They further revealed that apoptosis was induced by cannabidiol as shown by increased subG0/G1 and apoptosis through annexin V. Apoptosis was confirmed by overexpression of p53, caspase 3 and bax. Apoptosis induction was further confirmed by morphological changes, an increase in Caspase 3/7 and a decrease in the ATP levels. In conclusion, these data suggest that cannabidiol rather than Cannabis sativa crude extracts prevent cell growth and induce cell death in cervical cancer cell lines.

Resolved atomic lines reveal outflows in two ultraluminous X-ray sources.

PubMed

Pinto, Ciro; Middleton, Matthew J; Fabian, Andrew C

2016-05-05

Ultraluminous X-ray sources are extragalactic, off-nucleus, point sources in galaxies, and have X-ray luminosities in excess of 3 × 10(39) ergs per second. They are thought to be powered by accretion onto a compact object. Possible explanations include accretion onto neutron stars with strong magnetic fields, onto stellar-mass black holes (of up to 20 solar masses) at or in excess of the classical Eddington limit, or onto intermediate-mass black holes (10(3)-10(5) solar masses). The lack of sufficient energy resolution in previous analyses has prevented an unambiguous identification of any emission or absorption lines in the X-ray band, thereby precluding a detailed analysis of the accretion flow. Here we report the presence of X-ray emission lines arising from highly ionized iron, oxygen and neon with a cumulative significance in excess of five standard deviations, together with blueshifted (about 0.2 times light velocity) absorption lines of similar significance, in the high-resolution X-ray spectra of the ultraluminous X-ray sources NGC 1313 X-1 and NGC 5408 X-1. The blueshifted absorption lines must occur in a fast-outflowing gas, whereas the emission lines originate in slow-moving gas around the source. We conclude that the compact object in each source is surrounded by powerful winds with an outflow velocity of about 0.2 times that of light, as predicted by models of accreting supermassive black holes and hyper-accreting stellar-mass black holes.

40 CFR 467.55 - Pretreatment standards for existing sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... any 1 day Maximum for monthly average mg/off-kg (lb/million off-lbs) of aluminum drawn with neat oils Chromium 0.022 0.009 Cyanide 0.015 0.006 Zinc 0.073 0.031 TTO 0.035 Oil and grease (alternate monitoring...) EFFLUENT GUIDELINES AND STANDARDS ALUMINUM FORMING POINT SOURCE CATEGORY Drawing With Neat Oils Subcategory...

10 CFR 36.21 - Performance criteria for sealed sources.

Code of Federal Regulations, 2014 CFR

2014-01-01

... to an external pressure (absolute) of 2 million newtons per square meter. (d) Impact. A 2-kilogram steel weight, 2.5 centimeters in diameter, must be dropped from a height of 1 meter onto the test source... from 25 hertz to 500 hertz with a peak amplitude of 5 times the acceleration of gravity. In addition...

10 CFR 36.21 - Performance criteria for sealed sources.

Code of Federal Regulations, 2012 CFR

2012-01-01

... to an external pressure (absolute) of 2 million newtons per square meter. (d) Impact. A 2-kilogram steel weight, 2.5 centimeters in diameter, must be dropped from a height of 1 meter onto the test source... from 25 hertz to 500 hertz with a peak amplitude of 5 times the acceleration of gravity. In addition...

10 CFR 36.21 - Performance criteria for sealed sources.

Code of Federal Regulations, 2013 CFR

2013-01-01

... to an external pressure (absolute) of 2 million newtons per square meter. (d) Impact. A 2-kilogram steel weight, 2.5 centimeters in diameter, must be dropped from a height of 1 meter onto the test source... from 25 hertz to 500 hertz with a peak amplitude of 5 times the acceleration of gravity. In addition...

10 CFR 36.21 - Performance criteria for sealed sources.

Code of Federal Regulations, 2011 CFR

2011-01-01

... to an external pressure (absolute) of 2 million newtons per square meter. (d) Impact. A 2-kilogram steel weight, 2.5 centimeters in diameter, must be dropped from a height of 1 meter onto the test source... from 25 hertz to 500 hertz with a peak amplitude of 5 times the acceleration of gravity. In addition...

Imprint of DESI fiber assignment on the anisotropic power spectrum of emission line galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pinol, Lucas; Cahn, Robert N.; Hand, Nick

The Dark Energy Spectroscopic Instrument (DESI), a multiplexed fiber-fed spectrograph, is a Stage-IV ground-based dark energy experiment aiming to measure redshifts for 29 million Emission-Line Galaxies (ELG), 4 million Luminous Red Galaxies (LRG), and 2 million Quasi-Stellar Objects (QSO). The survey design includes a pattern of tiling on the sky, the locations of the fiber positioners in the focal plane of the telescope, and an observation strategy determined by a fiber assignment algorithm that optimizes the allocation of fibers to targets. This strategy allows a given region to be covered on average five times for a five-year survey, with amore » typical variation of about 1.5 about the mean, which imprints a spatially-dependent pattern on the galaxy clustering. We investigate the systematic effects of the fiber assignment coverage on the anisotropic galaxy clustering of ELGs and show that, in the absence of any corrections, it leads to discrepancies of order ten percent on large scales for the power spectrum multipoles. We introduce a method where objects in a random catalog are assigned a coverage, and the mean density is separately computed for each coverage factor. We show that this method reduces, but does not eliminate the effect. We next investigate the angular dependence of the contaminated signal, arguing that it is mostly localized to purely transverse modes. We demonstrate that the cleanest way to remove the contaminating signal is to perform an analysis of the anisotropic power spectrum P ( k ,μ) and remove the lowest μ bin, leaving μ > 0 modes accurate at the few-percent level. Here, μ is the cosine of the angle between the line-of-sight and the direction of k-vector . We also investigate two alternative definitions of the random catalog and show that they are comparable but less effective than the coverage randoms method.« less

Cost-effectiveness analysis of EGFR mutation testing and gefitinib as first-line therapy for non-small cell lung cancer.

PubMed

Narita, Yusuke; Matsushima, Yukiko; Shiroiwa, Takeru; Chiba, Koji; Nakanishi, Yoichi; Kurokawa, Tatsuo; Urushihara, Hisashi

2015-10-01

The combination use of gefitinib and epidermal growth factor receptor (EGFR) testing is a standard first-line therapy for patients with non-small cell lung cancer (NSCLC). Here, we examined the cost-effectiveness of this approach in Japan. Our analysis compared the 'EGFR testing strategy', in which EGFR mutation testing was performed before treatment and patients with EGFR mutations received gefitinib while those without mutations received standard chemotherapy, to the 'no-testing strategy,' in which genetic testing was not conducted and all patients were treated with standard chemotherapy. A three-state Markov model was constructed to predict expected costs and outcomes for each strategy. We included only direct medical costs from the healthcare payer's perspective. Outcomes in the model were based on those reported in the Iressa Pan-Asia Study (IPASS). The incremental cost-effectiveness ratio (ICER) was calculated using quality-adjusted life-years (QALYs) gained. Sensitivity and scenario analyses were conducted. The incremental cost and effectiveness per patient of the 'EGFR testing strategy' compared to the 'no-testing strategy' was estimated to be approximately JP¥122,000 (US$1180; US$1=JP¥104 as of February 2014) and 0.036 QALYs. The ICER was then calculated to be around JP¥3.38 million (US$32,500) per QALY gained. These results suggest that the 'EGFR testing strategy' is cost-effective compared with the 'no-testing strategy' when JP¥5.0 million to 6.0 million per QALY gained is considered an acceptable threshold. These results were supported by the sensitivity and scenario analyses. The combination use of gefitinib and EGFR testing can be considered a cost-effective first-line therapy compared to chemotherapy such as carboplatin-paclitaxel for the treatment for NSCLC in Japan. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Imprint of DESI fiber assignment on the anisotropic power spectrum of emission line galaxies

NASA Astrophysics Data System (ADS)

Pinol, Lucas; Cahn, Robert N.; Hand, Nick; Seljak, Uroš; White, Martin

2017-04-01

The Dark Energy Spectroscopic Instrument (DESI), a multiplexed fiber-fed spectrograph, is a Stage-IV ground-based dark energy experiment aiming to measure redshifts for 29 million Emission-Line Galaxies (ELG), 4 million Luminous Red Galaxies (LRG), and 2 million Quasi-Stellar Objects (QSO). The survey design includes a pattern of tiling on the sky, the locations of the fiber positioners in the focal plane of the telescope, and an observation strategy determined by a fiber assignment algorithm that optimizes the allocation of fibers to targets. This strategy allows a given region to be covered on average five times for a five-year survey, with a typical variation of about 1.5 about the mean, which imprints a spatially-dependent pattern on the galaxy clustering. We investigate the systematic effects of the fiber assignment coverage on the anisotropic galaxy clustering of ELGs and show that, in the absence of any corrections, it leads to discrepancies of order ten percent on large scales for the power spectrum multipoles. We introduce a method where objects in a random catalog are assigned a coverage, and the mean density is separately computed for each coverage factor. We show that this method reduces, but does not eliminate the effect. We next investigate the angular dependence of the contaminated signal, arguing that it is mostly localized to purely transverse modes. We demonstrate that the cleanest way to remove the contaminating signal is to perform an analysis of the anisotropic power spectrum P(k,μ) and remove the lowest μ bin, leaving μ > 0 modes accurate at the few-percent level. Here, μ is the cosine of the angle between the line-of-sight and the direction of vec k. We also investigate two alternative definitions of the random catalog and show that they are comparable but less effective than the coverage randoms method.

Model atmospheres for M (sub)dwarf stars. 1: The base model grid

NASA Technical Reports Server (NTRS)

Allard, France; Hauschildt, Peter H.

1995-01-01

We have calculated a grid of more than 700 model atmospheres valid for a wide range of parameters encompassing the coolest known M dwarfs, M subdwarfs, and brown dwarf candidates: 1500 less than or equal to T(sub eff) less than or equal to 4000 K, 3.5 less than or equal to log g less than or equal to 5.5, and -4.0 less than or equal to (M/H) less than or equal to +0.5. Our equation of state includes 105 molecules and up to 27 ionization stages of 39 elements. In the calculations of the base grid of model atmospheres presented here, we include over 300 molecular bands of four molecules (TiO, VO, CaH, FeH) in the JOLA approximation, the water opacity of Ludwig (1971), collision-induced opacities, b-f and f-f atomic processes, as well as about 2 million spectral lines selected from a list with more than 42 million atomic and 24 million molecular (H2, CH, NH, OH, MgH, SiH, C2, CN, CO, SiO) lines. High-resolution synthetic spectra are obtained using an opacity sampling method. The model atmospheres and spectra are calculated with the generalized stellar atmosphere code PHOENIX, assuming LTE, plane-parallel geometry, energy (radiative plus convective) conservation, and hydrostatic equilibrium. The model spectra give close agreement with observations of M dwarfs across a wide spectral range from the blue to the near-IR, with one notable exception: the fit to the water bands. We discuss several practical applications of our model grid, e.g., broadband colors derived from the synthetic spectra. In light of current efforts to identify genuine brown dwarfs, we also show how low-resolution spectra of cool dwarfs vary with surface gravity, and how the high-regulation line profile of the Li I resonance doublet depends on the Li abundance.

Earth observations taken during STS-77 mission

NASA Image and Video Library

1996-05-28

STS077-732-093 (19-29 May 1996) --- This high oblique perspective from the Space Shuttle Endeavour shows the Dead Sea Rift Valley and the surrounding deserts. North is to the right side of the frame. The vegetation line on the coast between Egypt and Israel is clearly visible. Crete is visible in the Mediterranean Sea. The Dead Sea was formed approximately 3 million years ago. A passage opened up to the sea and the water poured in. It is about 1,300 feet below sea level. It is fed by the Jordan River and numerous mineral springs from the surrounding hills. It is estimated to contain 43 million metric tons of salt. The salinity is 32 percent.

Onion dehydration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lund, J.W.

1995-12-31

Onion dehydration consists of a continuous operation, belt conveyor using fairly low-temperature hot air from 38-104{degrees}C (100 to 200{degrees}F). Typical processing plants will handle 4500 kg (10,000 pounds) of raw product per hour (single line), reducing the moisture from around 83 % to 4 % (680 to 820 kg - 1,500 to 1,800 pounds finished product). An example of a geothermal processing plant is Integrate Ingredients at Empire, Nevada, in the San Emidio Desert. A total of 6.3 million kg (14 million pounds) of dry product are produced annually: 60% onion and 40% garlic. A 130{degrees}C (266{degrees}F) well provide themore » necessary heat for the plant.« less

Light Sources and Lighting Circuits

NASA Astrophysics Data System (ADS)

Honda, Hisashi; Suwa, Takumi; Yasuda, Takeo; Ohtani, Yoshihiko; Maehara, Akiyoshi; Okada, Atsunori; Komatsu, Naoki; Mannami, Tomoaki

According to the Machinery Statistics of the Ministry of Economy, Trade and Industry, the production of incandescent lamps in Japan in 2007 was 990 million units (90.0% of the previous year's total), in which the production of incandescent lamps for general lighting was 110 million units (90.0% of the previous year's total) and of tungsten-halogen lamps was 44 million units (96.6% of the previous year's total). The production of fluorescent lamps was 927 million units (93.9% of the previous year's total), in which general fluorescent lamps, excluding those for LCD back lighting, was 320 million units (87.2% of the previous year's total). Also, the production of HID lamps was 10 million units (101.5% of the previous year's total). On the other hand, when the numbers of sales are compared with the sales of the previous year, incandescent lamps for general use was 99.8%, tungsten-halogen lamps was 96.9%, fluorescent lamps was 95.9%, and HID lamps was 98.9%. Self-ballasted fluorescent lamps alone showed an increase in sales as strong as 29 million units, or 121.7% of the previous year's sales. It is considered that the switchover of incandescent lamps to HID lamps was promoted for energy conservation and carbon dioxide reduction with the problem of global warming in the background. In regard to exhibitions, Lighting Fair 2007 was held in Tokyo in March, and LIGHTFAIR INTERNATIONAL 2007 was held in New York in May. Regarding academic conferences, LS:11 (the 11th International Symposium on the Science & Technology of Light Sources) was held in Shanghai in May, and the First International Conference on White LEDs and Solid State Lighting was held in Tokyo in November. Both conferences suggested that there are strong needs and concerns now about energy conservation, saving natural resources, and restrictions of hazardous materials. In regard to incandescent lamps, the development of products aiming at higher efficacy, electric power savings, and longer life was advanced by means of using filler gas with a higher atomic weight. Regarding fluorescent lamps, studies and developments for longer operating life and improvement in the lumen maintenance factor for the straight-type and circular-type fluorescent lamps were actively pursued. Regarding self-ballasted fluorescent lamps, the main stream of development was aimed at reducing lamp size and increasing energy conservation, and the development of new products that took advantage of these features proceeded. In regard to LED light sources, basic research and product development, including new application development, were vigorously implemented. In basic research, studies were reported, not only on efficacy improvements through optimization of the LED chips, phosphor layers, and packaging technology, but also on photometry, colorimetry, and visual psychology. In the field of application, applications were studied for general lighting sources and also for a wide range of fields, such as automotive headlights and visible light communication. Also, many academic conferences and exhibitions were held domestically and overseas, and the high level of interest suggests high expectations for this next-generation light source. Regarding HID lamps, there was much activity in research and development and in the commercialization of the ceramic metal halide lamp product, and products were commercialized with features such as higher efficiency (130 lm/W) and higher color rendering properties (R9 ≥ 90). In the high-pressure sodium lamps, there were many study reports concerning plant growth and insect pest control using its low insect-attracting characteristics. With high-pressure mercury lamps, there were many reports on reducing lamp size and increasing intensity for use as a light source for projectors.

Mercury's Na Exosphere from MESSENGER Data

NASA Technical Reports Server (NTRS)

Killen, Rosemary M.; Burger, M. H.; Cassidy, T. A.; Sarantos, M.; Vervack, R. J.; McClintock, W. El; Merkel, A. W.; Sprague, A. L.; Solomon, S. C.

2012-01-01

MESSENGER entered orbit about Mercury on March 18, 2011. Since then, the Ultraviolet and Visible Spectrometer (UWS) channel of MESSENGER's Mercury Atmospheric and Surface Composition Spectrometer (MASCS) has been observing Mercury's exosphere nearly continuously. Daily measurements of Na brightness were fitted with non-uniform exospheric models. With Monte Carlo sampling we traced the trajectories of a representative number of test particles, generally one million per run per source process, until photoionization, escape from the gravitational well, or permanent sticking at the surface removed the atom from the simulation. Atoms were assumed to partially thermally accommodate on each encounter with the surface with accommodation coefficient 0.25. Runs for different assumed source processes are run separately, scaled and co-added. Once these model results were saved onto a 3D grid, we ran lines of sight from the MESSENGER spacecraft :0 infinity using the SPICE kernels and we computed brightness integrals. Note that only particles that contribute to the measurement can be constrained with our method. Atoms and molecules produced on the nightside must escape the shadow in order to scatter light if the excitation process is resonant-light scattering, as assumed here. The aggregate distribution of Na atoms fits a 1200 K gas, with a PSD distribution, along with a hotter component. Our models constrain the hot component, assumed to be impact vaporization, to be emitted with a 2500 K Maxwellian. Most orbits show a dawnside enhancement in the hot component broadly spread over the leading hemisphere. However, on some dates there is no dawn/dusk asymmetry. The portion of the hot/cold source appears to be highly variable.

Testing AGN unification via inference from large catalogs

NASA Astrophysics Data System (ADS)

Nikutta, Robert; Ivezic, Zeljko; Elitzur, Moshe; Nenkova, Maia

2018-01-01

Source orientation and clumpiness of the central dust are the main factors in AGN classification. Type-1 QSOs are easy to observe and large samples are available (e.g. in SDSS), but obscured type-2 AGN are dimmer and redder as our line of sight is more obscured, making it difficult to obtain a complete sample. WISE has found up to a million QSOs. With only 4 bands and a relatively small aperture the analysis of individual sources is challenging, but the large sample allows inference of bulk properties at a very significant level.CLUMPY (www.clumpy.org) is arguably the most popular database of AGN torus SEDs. We model the ensemble properties of the entire WISE AGN content using regularized linear regression, with orientation-dependent CLUMPY color-color-magnitude (CCM) tracks as basis functions. We can reproduce the observed number counts per CCM bin with percent-level accuracy, and simultaneously infer the probability distributions of all torus parameters, redshifts, additional SED components, and identify type-1/2 AGN populations through their IR properties alone. We increase the statistical power of our AGN unification tests even further, by adding other datasets as axes in the regression problem. To this end, we make use of the NOAO Data Lab (datalab.noao.edu), which hosts several high-level large datasets and provides very powerful tools for handling large data, e.g. cross-matched catalogs, fast remote queries, etc.

Spectroscopic confirmation of a galaxy at redshift z = 8.6.

PubMed

Lehnert, M D; Nesvadba, N P H; Cuby, J-G; Swinbank, A M; Morris, S; Clément, B; Evans, C J; Bremer, M N; Basa, S

2010-10-21

Galaxies had their most significant impact on the Universe when they assembled their first generations of stars. Energetic photons emitted by young, massive stars in primeval galaxies ionized the intergalactic medium surrounding their host galaxies, cleared sightlines along which the light of the young galaxies could escape, and fundamentally altered the physical state of the intergalactic gas in the Universe continuously until the present day. Observations of the cosmic microwave background, and of galaxies and quasars at the highest redshifts, suggest that the Universe was reionized through a complex process that was completed about a billion years after the Big Bang, by redshift z ≈ 6. Detecting ionizing Lyman-α photons from increasingly distant galaxies places important constraints on the timing, location and nature of the sources responsible for reionization. Here we report the detection of Lyα photons emitted less than 600 million years after the Big Bang. UDFy-38135539 (ref. 5) is at a redshift of z = 8.5549 ± 0.0002, which is greater than those of the previously known most distant objects, at z = 8.2 (refs 6 and 7) and z = 6.96 (ref. 8). We find that this single source is unlikely to provide enough photons to ionize the volume necessary for the emission line to escape, requiring a significant contribution from other, probably fainter galaxies nearby.

Abandoned coal mine stores gas for Colorado peak-day demands

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brown, L.W.

1978-09-01

Since 1961, the Leyden Mine, from which 6 million tons of coal had been removed to leave a 150 million cu ft void, has been used for gas storage at 250 psig max pressure, after the hoisting and ventilation shafts had been sealed with concrete, rock, sand, and mud. Following several withdrawal expansions, a design for maximum delivery of 230 million cu ft/day for five days with a pressure drop in the cavern down to 100 psig was developed to satisfy customer requirements for peak shaving. This required redesigning the gathering system by looping large existing lines, eliminating inefficient ones,more » and drilling additional wells; installing three lightweight 3500-hp Centaur turbine/compressor units from Solar Turbines International to provide the minimum 200 psig compressor discharge pressure needed for gas distribution on peak usage days; and installing Donaldson Co. engine air-inlet silencers on the turbine inlets to reduce noise levels below the public code requirement. In the 1977-78 heating season, the Leyden facility produced 196 million cu ft/day of gas; with continued load growth and well drilling to reduce pressure loss, the maximum design flow rate will be attained.« less

Floods of January-February 1957 in southeastern Kentucky and adjacent areas

USGS Publications Warehouse

,

1964-01-01

Heavy rains over an extensive area on January 27-February 2, caused extreme flooding in southeastern Kentucky and adjacent areas in West Virginia, Virginia, and Tennessee. Total rainfall for the storm period ranged from 6-9 inches over most of the report area and was 12? inches at the eastern end of the Virginia-Kentucky State line. The principal basins affected by the storm were those of the Big Sandy, Kentucky, Cumberland, and Tennessee Rivers. Maximum discharge of record occurred in many streams. On Levisa Fork near Grundy, Va., the peak discharge of 33,200 cfs was 50 percent greater than the previous maximum in 17 years of record and was 3.3 times the mean annual flood. The peak discharges on-tributaries of the Kentucky River and on ,the Holston and Clinch Rivers were also the greatest of record and .those on the upper Cumberland River were nearly as great as .those during the historic floods of 1918 and 1946. Total flood damage was estimated at $61 million of which $39 million was in the Big Sandy River basin (mostly in Kentucky) and $15 million was in the Kentucky River basin--$52 million of the total damage was in Kentucky.

Costs analysis of a population level rabies control programme in Tamil Nadu, India.

PubMed

Abbas, Syed Shahid; Kakkar, Manish; Rogawski, Elizabeth Tacket

2014-02-01

The study aimed to determine costs to the state government of implementing different interventions for controlling rabies among the entire human and animal populations of Tamil Nadu. This built upon an earlier assessment of Tamil Nadu's efforts to control rabies. Anti-rabies vaccines were made available at all health facilities. Costs were estimated for five different combinations of animal and human interventions using an activity-based costing approach from the provider perspective. Disease and population data were sourced from the state surveillance data, human census and livestock census. Program costs were extrapolated from official documents. All capital costs were depreciated to estimate annualized costs. All costs were inflated to 2012 Rupees. Sensitivity analysis was conducted across all major cost centres to assess their relative impact on program costs. It was found that the annual costs of providing Anti-rabies vaccine alone and in combination with Immunoglobulins was $0.7 million (Rs 36 million) and $2.2 million (Rs 119 million), respectively. For animal sector interventions, the annualised costs of rolling out surgical sterilisation-immunization, injectable immunization and oral immunizations were estimated to be $ 44 million (Rs 2,350 million), $23 million (Rs 1,230 million) and $ 11 million (Rs 590 million), respectively. Dog bite incidence, health systems coverage and cost of rabies biologicals were found to be important drivers of costs for human interventions. For the animal sector interventions, the size of dog catching team, dog population and vaccine costs were found to be driving the costs. Rabies control in Tamil Nadu seems a costly proposition the way it is currently structured. Policy makers in Tamil Nadu and other similar settings should consider the long-term financial sustainability before embarking upon a state or nation-wide rabies control programme.

Costs Analysis of a Population Level Rabies Control Programme in Tamil Nadu, India

PubMed Central

Abbas, Syed Shahid; Kakkar, Manish; Rogawski, Elizabeth Tacket

2014-01-01

The study aimed to determine costs to the state government of implementing different interventions for controlling rabies among the entire human and animal populations of Tamil Nadu. This built upon an earlier assessment of Tamil Nadu's efforts to control rabies. Anti-rabies vaccines were made available at all health facilities. Costs were estimated for five different combinations of animal and human interventions using an activity-based costing approach from the provider perspective. Disease and population data were sourced from the state surveillance data, human census and livestock census. Program costs were extrapolated from official documents. All capital costs were depreciated to estimate annualized costs. All costs were inflated to 2012 Rupees. Sensitivity analysis was conducted across all major cost centres to assess their relative impact on program costs. It was found that the annual costs of providing Anti-rabies vaccine alone and in combination with Immunoglobulins was $0.7 million (Rs 36 million) and $2.2 million (Rs 119 million), respectively. For animal sector interventions, the annualised costs of rolling out surgical sterilisation-immunization, injectable immunization and oral immunizations were estimated to be $ 44 million (Rs 2,350 million), $23 million (Rs 1,230 million) and $ 11 million (Rs 590 million), respectively. Dog bite incidence, health systems coverage and cost of rabies biologicals were found to be important drivers of costs for human interventions. For the animal sector interventions, the size of dog catching team, dog population and vaccine costs were found to be driving the costs. Rabies control in Tamil Nadu seems a costly proposition the way it is currently structured. Policy makers in Tamil Nadu and other similar settings should consider the long-term financial sustainability before embarking upon a state or nation-wide rabies control programme. PMID:24587471

State-level medical and absenteeism cost of asthma in the United States.

PubMed

Nurmagambetov, Tursynbek; Khavjou, Olga; Murphy, Louise; Orenstein, Diane

2017-05-01

For medically treated asthma, we estimated prevalence, medical and absenteeism costs, and projected medical costs from 2015 to 2020 for the entire population and separately for children in the 50 US states and District of Columbia (DC) using the most recently available data. We used multiple data sources, including the Medical Expenditure Panel Survey, U.S. Census Bureau, Kaiser Family Foundation, Medical Statistical Information System, and Current Population Survey. We used a two-part regression model to estimate annual medical costs of asthma and a negative binomial model to estimate annual school and work days missed due to asthma. Per capita medical costs of asthma ranged from $1,860 (Mississippi) to $2,514 (Michigan). Total medical costs of asthma ranged from $60.7 million (Wyoming) to $3.4 billion (California). Medicaid costs ranged from $4.1 million (Wyoming) to $566.8 million (California), Medicare from $5.9 million (DC) to $446.6 million (California), and costs paid by private insurers ranged from $27.2 million (DC) to $1.4 billion (California). Total annual school and work days lost due to asthma ranged from 22.4 thousand (Wyoming) to 1.5 million days (California) and absenteeism costs ranged from $4.4 million (Wyoming) to $345 million (California). Projected increase in medical costs from 2015 to 2020 ranged from 9% (DC) to 34% (Arizona). Medical and absenteeism costs of asthma represent a significant economic burden for states and these costs are expected to rise. Our study results emphasize the urgency for strategies to strengthen state level efforts to prevent and control asthma attacks.

The Global Burden of Cancer 2013.

PubMed

Fitzmaurice, Christina; Dicker, Daniel; Pain, Amanda; Hamavid, Hannah; Moradi-Lakeh, Maziar; MacIntyre, Michael F; Allen, Christine; Hansen, Gillian; Woodbrook, Rachel; Wolfe, Charles; Hamadeh, Randah R; Moore, Ami; Werdecker, Andrea; Gessner, Bradford D; Te Ao, Braden; McMahon, Brian; Karimkhani, Chante; Yu, Chuanhua; Cooke, Graham S; Schwebel, David C; Carpenter, David O; Pereira, David M; Nash, Denis; Kazi, Dhruv S; De Leo, Diego; Plass, Dietrich; Ukwaja, Kingsley N; Thurston, George D; Yun Jin, Kim; Simard, Edgar P; Mills, Edward; Park, Eun-Kee; Catalá-López, Ferrán; deVeber, Gabrielle; Gotay, Carolyn; Khan, Gulfaraz; Hosgood, H Dean; Santos, Itamar S; Leasher, Janet L; Singh, Jasvinder; Leigh, James; Jonas, Jost B; Jonas, Jost; Sanabria, Juan; Beardsley, Justin; Jacobsen, Kathryn H; Takahashi, Ken; Franklin, Richard C; Ronfani, Luca; Montico, Marcella; Naldi, Luigi; Tonelli, Marcello; Geleijnse, Johanna; Petzold, Max; Shrime, Mark G; Younis, Mustafa; Yonemoto, Naohiro; Breitborde, Nicholas; Yip, Paul; Pourmalek, Farshad; Lotufo, Paulo A; Esteghamati, Alireza; Hankey, Graeme J; Ali, Raghib; Lunevicius, Raimundas; Malekzadeh, Reza; Dellavalle, Robert; Weintraub, Robert; Lucas, Robyn; Hay, Roderick; Rojas-Rueda, David; Westerman, Ronny; Sepanlou, Sadaf G; Nolte, Sandra; Patten, Scott; Weichenthal, Scott; Abera, Semaw Ferede; Fereshtehnejad, Seyed-Mohammad; Shiue, Ivy; Driscoll, Tim; Vasankari, Tommi; Alsharif, Ubai; Rahimi-Movaghar, Vafa; Vlassov, Vasiliy V; Marcenes, W S; Mekonnen, Wubegzier; Melaku, Yohannes Adama; Yano, Yuichiro; Artaman, Al; Campos, Ismael; MacLachlan, Jennifer; Mueller, Ulrich; Kim, Daniel; Trillini, Matias; Eshrati, Babak; Williams, Hywel C; Shibuya, Kenji; Dandona, Rakhi; Murthy, Kinnari; Cowie, Benjamin; Amare, Azmeraw T; Antonio, Carl Abelardo; Castañeda-Orjuela, Carlos; van Gool, Coen H; Violante, Francesco; Oh, In-Hwan; Deribe, Kedede; Soreide, Kjetil; Knibbs, Luke; Kereselidze, Maia; Green, Mark; Cardenas, Rosario; Roy, Nobhojit; Tillmann, Taavi; Tillman, Taavi; Li, Yongmei; Krueger, Hans; Monasta, Lorenzo; Dey, Subhojit; Sheikhbahaei, Sara; Hafezi-Nejad, Nima; Kumar, G Anil; Sreeramareddy, Chandrashekhar T; Dandona, Lalit; Wang, Haidong; Vollset, Stein Emil; Mokdad, Ali; Salomon, Joshua A; Lozano, Rafael; Vos, Theo; Forouzanfar, Mohammad; Lopez, Alan; Murray, Christopher; Naghavi, Mohsen

2015-07-01

Cancer is among the leading causes of death worldwide. Current estimates of cancer burden in individual countries and regions are necessary to inform local cancer control strategies. To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 28 cancers in 188 countries by sex from 1990 to 2013. The general methodology of the Global Burden of Disease (GBD) 2013 study was used. Cancer registries were the source for cancer incidence data as well as mortality incidence (MI) ratios. Sources for cause of death data include vital registration system data, verbal autopsy studies, and other sources. The MI ratios were used to transform incidence data to mortality estimates and cause of death estimates to incidence estimates. Cancer prevalence was estimated using MI ratios as surrogates for survival data; YLDs were calculated by multiplying prevalence estimates with disability weights, which were derived from population-based surveys; YLLs were computed by multiplying the number of estimated cancer deaths at each age with a reference life expectancy; and DALYs were calculated as the sum of YLDs and YLLs. In 2013 there were 14.9 million incident cancer cases, 8.2 million deaths, and 196.3 million DALYs. Prostate cancer was the leading cause for cancer incidence (1.4 million) for men and breast cancer for women (1.8 million). Tracheal, bronchus, and lung (TBL) cancer was the leading cause for cancer death in men and women, with 1.6 million deaths. For men, TBL cancer was the leading cause of DALYs (24.9 million). For women, breast cancer was the leading cause of DALYs (13.1 million). Age-standardized incidence rates (ASIRs) per 100 000 and age-standardized death rates (ASDRs) per 100 000 for both sexes in 2013 were higher in developing vs developed countries for stomach cancer (ASIR, 17 vs 14; ASDR, 15 vs 11), liver cancer (ASIR, 15 vs 7; ASDR, 16 vs 7), esophageal cancer (ASIR, 9 vs 4; ASDR, 9 vs 4), cervical cancer (ASIR, 8 vs 5; ASDR, 4 vs 2), lip and oral cavity cancer (ASIR, 7 vs 6; ASDR, 2 vs 2), and nasopharyngeal cancer (ASIR, 1.5 vs 0.4; ASDR, 1.2 vs 0.3). Between 1990 and 2013, ASIRs for all cancers combined (except nonmelanoma skin cancer and Kaposi sarcoma) increased by more than 10% in 113 countries and decreased by more than 10% in 12 of 188 countries. Cancer poses a major threat to public health worldwide, and incidence rates have increased in most countries since 1990. The trend is a particular threat to developing nations with health systems that are ill-equipped to deal with complex and expensive cancer treatments. The annual update on the Global Burden of Cancer will provide all stakeholders with timely estimates to guide policy efforts in cancer prevention, screening, treatment, and palliation.

The Global Burden of Cancer 2013

PubMed Central

2015-01-01

IMPORTANCE Cancer is among the leading causes of death worldwide. Current estimates of cancer burden in individual countries and regions are necessary to inform local cancer control strategies. OBJECTIVE To estimate mortality, incidence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs) for 28 cancers in 188 countries by sex from 1990 to 2013. EVIDENCE REVIEW The general methodology of the Global Burden of Disease (GBD) 2013 study was used. Cancer registries were the source for cancer incidence data as well as mortality incidence (MI) ratios. Sources for cause of death data include vital registration system data, verbal autopsy studies, and other sources. The MI ratios were used to transform incidence data to mortality estimates and cause of death estimates to incidence estimates. Cancer prevalence was estimated using MI ratios as surrogates for survival data; YLDs were calculated by multiplying prevalence estimates with disability weights, which were derived from population-based surveys; YLLs were computed by multiplying the number of estimated cancer deaths at each age with a reference life expectancy; and DALYs were calculated as the sum of YLDs and YLLs. FINDINGS In 2013 there were 14.9 million incident cancer cases, 8.2 million deaths, and 196.3 million DALYs. Prostate cancer was the leading cause for cancer incidence (1.4 million) for men and breast cancer for women (1.8 million). Tracheal, bronchus, and lung (TBL) cancer was the leading cause for cancer death in men and women, with 1.6 million deaths. For men, TBL cancer was the leading cause of DALYs (24.9 million). For women, breast cancer was the leading cause of DALYs (13.1 million). Age-standardized incidence rates (ASIRs) per 100 000 and age-standardized death rates (ASDRs) per 100 000 for both sexes in 2013 were higher in developing vs developed countries for stomach cancer (ASIR, 17 vs 14; ASDR, 15 vs 11), liver cancer (ASIR, 15 vs 7; ASDR, 16 vs 7), esophageal cancer (ASIR, 9 vs 4; ASDR, 9 vs 4), cervical cancer (ASIR, 8 vs 5; ASDR, 4 vs 2), lip and oral cavity cancer (ASIR, 7 vs 6; ASDR, 2 vs 2), and nasopharyngeal cancer (ASIR, 1.5 vs 0.4; ASDR, 1.2 vs 0.3). Between 1990 and 2013, ASIRs for all cancers combined (except nonmelanoma skin cancer and Kaposi sarcoma) increased by more than 10% in 113 countries and decreased by more than 10% in 12 of 188 countries. CONCLUSIONS AND RELEVANCE Cancer poses a major threat to public health worldwide, and incidence rates have increased in most countries since 1990. The trend is a particular threat to developing nations with health systems that are ill-equipped to deal with complex and expensive cancer treatments. The annual update on the Global Burden of Cancer will provide all stakeholders with timely estimates to guide policy efforts in cancer prevention, screening, treatment, and palliation. PMID:26181261

Spatial patterns of mobile source particulate matter emissions-to-exposure relationships across the United States

NASA Astrophysics Data System (ADS)

Greco, Susan L.; Wilson, Andrew M.; Spengler, John D.; Levy, Jonathan I.

Assessing the public health benefits from air pollution control measures is assisted by understanding the relationship between mobile source emissions and subsequent fine particulate matter (PM 2.5) exposure. Since this relationship varies by location, we characterized its magnitude and geographic distribution using the intake fraction (iF) concept. We considered emissions of primary PM 2.5 as well as particle precursors SO 2 and NO x from each of 3080 counties in the US. We modeled the relationship between these emissions and total US population exposure to PM 2.5, making use of a source-receptor matrix developed for health risk assessment. For primary PM 2.5, we found a median iF of 1.2 per million, with a range of 0.12-25. Half of the total exposure was reached by a median distance of 150 km from the county where mobile source emissions originated, though this spatial extent varied across counties from within the county borders to 1800 km away. For secondary ammonium sulfate from SO 2 emissions, the median iF was 0.41 per million (range: 0.050-10), versus 0.068 per million for secondary ammonium nitrate from NO x emissions (range: 0.00092-1.3). The median distance to half of the total exposure was greater for secondary PM 2.5 (450 km for sulfate, 390 km for nitrate). Regression analyses using exhaustive population predictors explained much of the variation in primary PM 2.5 iF ( R2=0.83) as well as secondary sulfate and nitrate iF ( R2=0.74 and 0.60), with greater near-source contribution for primary than for secondary PM 2.5. We conclude that long-range dispersion models with coarse geographic resolution are appropriate for risk assessments of secondary PM 2.5 or primary PM 2.5 emitted from mobile sources in rural areas, but that more resolved dispersion models are warranted for primary PM 2.5 in urban areas due to the substantial contribution of near-source populations.

Source Contributions to Premature Mortality Due to Ambient Particulate Matter in China

NASA Astrophysics Data System (ADS)

Hu, J.; Huang, L.; Ying, Q.; Zhang, H.; Shi, Z.

2016-12-01

Outdoor air pollution is linked to various health effects. Globally it is estimated that ambient air pollution caused 3.3 million premature deaths in 2010. The health risk occurs predominantly in developing countries, particularly in Asia. China has been suffering serious air pollution in recent decades. The annual concentrations of ambient PM2.5 are more than five times higher than the WHO guideline value in many populous Chinese cities. Sustained exposure to high PM2.5 concentrations greatly threatens public health in this country. Recognizing the severity of the air pollution situation, the Chinese government has set a target in 2013 to reduce PM2.5 level by up to 25% in major metropolitan areas by 2017. It is urgently needed for China to assess premature mortality caused by outdoor air pollution, identify source contributions of the premature mortality, and evaluate responses of the premature mortality to air quality improvement, in order to design effective control plans and set priority for air pollution controls to better protect public health. In this study, we determined the spatial distribution of excess mortality (ΔMort) due to adult (> 30 years old) ischemic heart disease (IHD), cerebrovascular disease (CEV), chronic obstructive pulmonary disease (COPD) and lung cancer (LC) at 36-km horizontal resolution for 2013 from the predicted annual-average surface PM2.5 concentrations using an updated source-oriented Community Multiscale Air Quality (CMAQ) model along with an ensemble of four regional and global emission inventories. Observation data fusing was applied to provide additional correction of the biases in the PM2.5 concentration field from the ensemble. Source contributions to ΔMort were determined based on total ΔMort and fractional source contributions to PM2.5 mass concentrations. We estimated that ΔMort due to COPD, LC, IHD and CEV are 0.329, 0.148, 0.239 and 0.953 million in China, respectively, leading to a total ΔMort of 1.669 million. Industries and residential sources were the two leading sources to ΔMort, contributing to 0.508 (30.5%) and 0.366 (21.9%) mp, respectively. Secondary ammonium ion from agriculture sources, secondary organic aerosol and aerosols from power generation sources were responsible for ΔMort of 0.204, 0.179 and 0.172 mp, respectively.

Continuous discharge Penning source with emission lines between 50 A and 300 A. [for astronomy

NASA Technical Reports Server (NTRS)

Finley, D. S.; Bowyer, S.; Paresce, F.; Malina, R. F.

1979-01-01

The present paper deals with a modified Penning discharge lamp developed specially to cover the soft X-ray and extreme UV spectral regions. The source produces a total of nearly 40 intense lines in the 50 to 300 A range. The lamp is quiet, continuous, and stable over most of the cathode lifetime (which is sufficient for long calibration runs). When the cathodes become exhausted, the refurbishment procedure is so simple that the source can be back on line in an hour or less

Cyclotron Line Measurements with INTEGRAL

NASA Technical Reports Server (NTRS)

Pottschmidt, K.; Kreykenbohm, I.; Caballero, I.; Fritz, S.; Schoenherr, G.; Kretschmar, P.; Wilms, J.; McBride, V. A.; Suchy, S.; Rothschild, R. E.

2008-01-01

Due to its broadband energy coverage, INTEGRAL has made important contributions to observing and interpreting cyclotron lines, which are present in the 10-100 keV range of a sample of accreting pulsars. In these systems photons with energies fulfilling the resonance condition inelastically Compton scatter off electrons quantized in the accretion column above the neutron star's magnetic pole(s). This process gives rise to the broad, absorption-like lines or 'cyclotron resonant scattering features' (CRSF). The observed lines allow to directly measure the B-fields of these sources, resulting in values of a few times 1E12G. In this overview I will present recent highlights regarding CRSF observations as well as discuss current ideas and models for the physical conditions in the accretion column. Among the former are the stability of the spectrum of Vela X-1 during giant flares in 2003, the observation of three cyclotron lines during the 2004 outburst of V0332+53, the confirmation of the fundamental line at approximately 45 keV during a 2005 normal outburst of A0535-26, and the simultaneous detection of the two lines in the dipping source 4U 1907+09 (for which also a torque reversal was detected for the first time). Through these and other observations it has become increasingly apparent that two types of observations can potentially be used to constrain the accretion column geometry: the determination of energy ratios for multiple harmonic lines (only two sources with greater than 2 lines are known), was well as the evolution of the fundamental line centroid, which, for different sources, may or may not be correlated with flux. Furthermore, first steps have been taken away from the usual phenomenological description of the lines, towards a physical approach based on self-consistent CRSF modeling. Initial applications are presented.

40 CFR 63.1345 - Emissions limits for affected sources other than kilns; in-line kiln/raw mills; clinker coolers...

Code of Federal Regulations, 2011 CFR

2011-07-01

... other than kilns; in-line kiln/raw mills; clinker coolers; new and reconstructed raw material dryers; and raw and finish mills, and open clinker piles. 63.1345 Section 63.1345 Protection of Environment... for affected sources other than kilns; in-line kiln/raw mills; clinker coolers; new and reconstructed...

UK investments in global infectious disease research 1997-2010: a case study.

PubMed

Head, Michael G; Fitchett, Joseph R; Cooke, Mary K; Wurie, Fatima B; Hayward, Andrew C; Atun, Rifat

2013-01-01

Infectious diseases account for 15 million deaths per year worldwide, and disproportionately affect young people, elderly people, and the poorest sections of society. We aimed to describe the investments awarded to UK institutions for infectious disease research. We systematically searched databases and websites for information on research studies from funding institutions and created a comprehensive database of infectious disease research projects for the period 1997-2010. We categorised studies and funding by disease, cross-cutting theme, and by a research and development value chain describing the type of science. Regression analyses were reported with Spearman's rank correlation coefficient to establish the relation between research investment, mortality, and disease burden as measured by disability-adjusted life years (DALYs). We identified 6170 funded studies, with a total research investment of UK£2·6 billion. Studies with a clear global health component represented 35·6% of all funding (£927 million). By disease, HIV received £461 million (17·7%), malaria £346 million (13·3%), tuberculosis £149 million (5·7%), influenza £80 million (3·1%), and hepatitis C £60 million (2·3%). We compared funding with disease burden (DALYs and mortality) to show low levels of investment relative to burden for gastrointestinal infections (£254 million, 9·7%), some neglected tropical diseases (£184 million, 7·1%), and antimicrobial resistance (£96 million, 3·7%). Virology was the highest funded category (£1 billion, 38·4%). Leading funding sources were the Wellcome Trust (£688 million, 26·4%) and the Medical Research Council (£673 million, 25·8%). Research funding has to be aligned with prevailing and projected global infectious disease burden. Funding agencies and industry need to openly document their research investments to redress any inequities in resource allocation. None. Copyright © 2013 Elsevier Ltd. All rights reserved.

Estimation of the number and demographics of companion dogs in the UK

PubMed Central

2011-01-01

Background Current estimates of the UK dog population vary, contain potential sources of bias and are based on expensive, large scale, public surveys. Here, we evaluate the potential of a variety of sources for estimation and monitoring of the companion dog population in the UK and associated demographic information. The sources considered were: a public survey; veterinary practices; pet insurance companies; micro-chip records; Kennel Club registrations; and the Pet Travel Scheme. The public survey and subpopulation estimates from veterinary practices, pet insurance companies and Kennel Club registrations, were combined to generate distinct estimates of the UK owned dog population using a Bayesian approach. Results We estimated there are 9.4 (95% CI: 8.1-11.5) million companion dogs in the UK according to the public survey alone, which is similar to other recent estimates. The population was judged to be over-estimated by combining the public and veterinary surveys (16.4, 95% CI: 12.5-21.5 million) and under-estimated by combining the public survey and insured dog numbers (4.8, 95% CI: 3.6-6.9 million). An estimate based on combining the public survey and Kennel Club registered dogs was 7.1 (95% CI: 4.5-12.9) million. Based on Bayesian estimations, 77 (95% CI: 62-92)% of the UK dog population were registered at a veterinary practice; 42 (95% CI: 29-55)% of dogs were insured; and 29 (95% CI: 17-43)% of dogs were Kennel Club registered. Breed demographics suggested the Labrador was consistently the most popular breed registered in micro-chip records, with the Kennel Club and with J. Sainsbury's PLC pet insurance. A comparison of the demographics between these sources suggested that popular working breeds were under-represented and certain toy, utility and miniature breeds were over- represented in the Kennel Club registrations. Density maps were produced from micro-chip records based on the geographical distribution of dogs. Conclusions A list containing the breed of each insured dog was provided by J. Sainsbury's PLC pet insurance without any accompanying information about the dog or owner. PMID:22112367

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gutiérrez, Carlos M.; Moon, Dae-Sik, E-mail: cgc@iac.es

We present the identification and characterization of the optical counterpart to 2XMM J011942.7+032421, one of the most luminous and distant ultra-luminous X-ray sources (ULXs). The counterpart is located near a star-forming region in a spiral arm of the galaxy NGC 470 with u, g, and r magnitudes of 21.53, 21.69, and 21.71 mag, respectively. The luminosity of the counterpart is much larger than that of a single O-type star, indicating that it may be a stellar cluster. Our optical spectroscopic observations confirm the association of the X-ray source and the optical counterpart with its host galaxy NGC 470, which validates the high,more » ≳10{sup 41} erg s{sup -1}, X-ray luminosity of the source. Its optical spectrum is embedded with numerous emission lines, including H recombination lines, metallic forbidden lines, and more notably the high-ionization He II (λ4686) line. That line shows a large velocity dispersion of ≅410 km s{sup -1}, consistent with the existence of a compact (<5 AU) highly ionized accretion disk rotating around the central X-ray source. The ∼1.4 × 10{sup 37} erg s{sup -1} luminosity of the He II line emission makes the source one of the most luminous ULXs in that emission. This, together with the high X-ray luminosity and the large velocity dispersion of the He II emission, suggests that the source is an ideal candidate for more extensive follow-up observations for understanding the nature of hyper-luminous X-ray sources, a more luminous subgroup of ULXs, and more likely candidates for intermediate-mass black holes.« less

Advanced Fire Detector for Space Applications

NASA Technical Reports Server (NTRS)

Kutzner, Joerg

2012-01-01

A document discusses an optical carbon monoxide sensor for early fire detection. During the sensor development, a concept was implemented to allow reliable carbon monoxide detection in the presence of interfering absorption signals. Methane interference is present in the operating wavelength range of the developed prototype sensor for carbon monoxide detection. The operating parameters of the prototype sensor have been optimized so that interference with methane is minimized. In addition, simultaneous measurement of methane is implemented, and the instrument automatically corrects the carbon monoxide signal at high methane concentrations. This is possible because VCSELs (vertical cavity surface emitting lasers) with extended current tuning capabilities are implemented in the optical device. The tuning capabilities of these new laser sources are sufficient to cover the wavelength range of several absorption lines. The delivered carbon monoxide sensor (COMA 1) reliably measures low carbon monoxide levels even in the presence of high methane signals. The signal bleed-over is determined during system calibration and is then accounted for in the system parameters. The sensor reports carbon monoxide concentrations reliably for (interfering) methane concentrations up to several thousand parts per million.

Bathymetric map of the south part of Great Salt Lake, Utah, 2005

USGS Publications Warehouse

Baskin, Robert L.; Allen, David V.

2005-01-01

The U.S. Geological Survey, in cooperation with the Utah Department of Natural Resources, Division of Wildlife Resources, collected bathymetric data for the south part of Great Salt Lake during 2002–04 using a single beam, high-definition fathometer and real-time differential global positioning system. Approximately 7.6 million depth readings were collected along more than 1,050 miles of survey transects for construction of this map. Sound velocities were obtained in conjunction with the bathymetric data to provide time-of-travel corrections to the depth calculations. Data were processed with commercial hydrographic software and exported into geographic information system (GIS) software for mapping. Because of the shallow nature of the lake and the limitations of the instrumentation, contours above an altitude of 4,193 feet were digitized from existing USGS 1:24,000 source-scale digital line graph data.For additional information on methods used to derive the bathymetric contours for this map, please see Baskin, Robert L., 2005, Calculation of area and volume for the south part of Great Salt Lake, Utah, U.S. Geological Survey Open-File Report OFR–2005–1327.

Solar Magnetized Tornadoes: Rotational Motion in a Tornado-like Prominence

NASA Astrophysics Data System (ADS)

Su, Yang; Gömöry, Peter; Veronig, Astrid; Temmer, Manuela; Wang, Tongjiang; Vanninathan, Kamalam; Gan, Weiqun; Li, YouPing

2014-04-01

Su et al. proposed a new explanation for filament formation and eruption, where filament barbs are rotating magnetic structures driven by underlying vortices on the surface. Such structures have been noticed as tornado-like prominences when they appear above the limb. They may play a key role as the source of plasma and twist in filaments. However, no observations have successfully distinguished rotational motion of the magnetic structures in tornado-like prominences from other motions such as oscillation and counter-streaming plasma flows. Here we report evidence of rotational motions in a tornado-like prominence. The spectroscopic observations in two coronal lines were obtained from a specifically designed Hinode/EIS observing program. The data revealed the existence of both cold and million-degree-hot plasma in the prominence leg, supporting the so-called prominence-corona transition region. The opposite velocities at the two sides of the prominence and their persistent time evolution, together with the periodic motions evident in SDO/AIA dark structures, indicate a rotational motion of both cold and hot plasma with a speed of ~5 km s-1.

[Food labeling in Ecuador: implementation, results, and pending actions].

PubMed

Díaz, Adrián Alberto; Veliz, Paula Mariana; Rivas-Mariño, Gabriela; Mafla, Carina Vance; Altamirano, Luz María Martínez; Jones, Cecilia Vaca

2017-06-08

Noncommunicable diseases are the world's leading cause of death, responsible for 38 million deaths in 2012. This epidemic is primarily associated with smoking, excessive alcohol consumption, sedentary lifestyle, and changes in dietary patterns, characterized by diets high in sugar and saturated fat, typical of processed foods and sugar-sweetened beverages, plus low intake of fruits and vegetables. Ecuador is no exception to this epidemiological profile or to changes in eating patterns. Thus, Ecuador's government designed and implemented an action plan aimed at changing the obesogenic environment, which includes six strategic lines. One of these is implementation of a traffic-light nutritional labeling system for processed foods, in late 2014, aimed at guaranteeing people's right to timely, clear, accurate, and non-deceptive information on the content and characteristics of these foods. This article analyzes implementation of processed food labeling and results to date, and proposes complementary measures needed to reach the goal in the National Plan for Good Living, in light of new scientific evidence and different agreements and regulatory frameworks in our Region. Methods included a literature and documentary review, key informant interviews, and analysis and processing of secondary sources.

The origin of intermediary metabolism

NASA Technical Reports Server (NTRS)

Morowitz, H. J.; Kostelnik, J. D.; Yang, J.; Cody, G. D.

2000-01-01

The core of intermediary metabolism in autotrophs is the citric acid cycle. In a certain group of chemoautotrophs, the reductive citric acid cycle is an engine of synthesis, taking in CO(2) and synthesizing the molecules of the cycle. We have examined the chemistry of a model system of C, H, and O that starts with carbon dioxide and reductants and uses redox couples as the energy source. To inquire into the reaction networks that might emerge, we start with the largest available database of organic molecules, Beilstein on-line, and prune by a set of physical and chemical constraints applicable to the model system. From the 3.5 million entries in Beilstein we emerge with 153 molecules that contain all 11 members of the reductive citric acid cycle. A small number of selection rules generates a very constrained subset, suggesting that this is the type of reaction model that will prove useful in the study of biogenesis. The model indicates that the metabolism shown in the universal chart of pathways may be central to the origin of life, is emergent from organic chemistry, and may be unique.

Uzbek licensing round brings geology, potential into focus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heafford, A.P.; Lichtman, G.S.

1993-08-09

Uzbekistan is a Central Asian Republic that declared independence from the former Soviet Union in 1991. Uzbekistan produces about 18 million bbl/year of oil and 40 bcf/year of gas. It is the third largest gas producer in the Commonwealth of Independent States and imports oil. The Uzbek government and oil and gas industry are offering exploration acreage for foreign participation via competitive bid. Acreage on offer includes fields for development and unproven-underexplored areas. Terms awaiting approval by the Cabinet of Ministers provide financial incentives for rapid development of existing reserves, creation of required infrastructure, and long term investment growth. Licensemore » areas concentrate on acreage where western equipment and technology can bring new reserves economically on line in the near future. National oil company Uzbekneftegaz was created in 1992 to oversee the extraction, transport, and refining of hydrocarbons in Uzbekistan. The paper describes some of the fields and infrastructure in place, the structural geology, stratigraphy, petroleum distribution, source rocks, reservoir rocks, cap rocks, traps, and hydrocarbon composition, which includes oil, gases, and gas condensates.« less

Bipolar outflows and Jets From Young Stars

NASA Astrophysics Data System (ADS)

Bally, J.

2000-05-01

Stars produce powerful jets and winds during their birth. These primary outflows power shock waves (Herbig-Haro objects) and entrain surrounding gas to produce molecular outflows. Many outflows reach parsec-scale dimensions whose dynamical ages can become comparable to the accretion age of the source star. Thus, these giant outflows provide fossil records of the mass loss histories of their parent stars. Jet symmetries provide tantalizing clues about the violent history of stellar accretion and dynamical interactions with nearby companions. These flows inject sufficient energy and momentum into the surrounding medium to alter the physical and chemical state of the gas, generate turbulence, disrupt the parent cloud, and self-regulate the rate of star formation. Recent observations have revealed a new class of externally irradiated jets which are rendered visible by the light of nearby massive stars. Some of these jets appear to be millions of years old, indicating that outflow activity can persist for much longer than previously thought. Stellar jets provide ideal laboratories for the investigation of accretion powered outflows and associated shocks since their time-dependent behavior can be observed with a rich variety of spectral line diagnostics.

WISE PHOTOMETRY FOR 400 MILLION SDSS SOURCES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lang, Dustin; Hogg, David W.; Schlegel, David J., E-mail: dstndstn@gmail.com

2016-02-15

We present photometry of images from the Wide-Field Infrared Survey Explorer (WISE) of over 400 million sources detected by the Sloan Digital Sky Survey (SDSS). We use a “forced photometry” technique, using measured SDSS source positions, star–galaxy classification, and galaxy profiles to define the sources whose fluxes are to be measured in the WISE images. We perform photometry with The Tractor image modeling code, working on our “unWISE” coaddds and taking account of the WISE point-spread function and a noise model. The result is a measurement of the flux of each SDSS source in each WISE band. Many sources havemore » little flux in the WISE bands, so often the measurements we report are consistent with zero given our uncertainties. However, for many sources we get 3σ or 4σ measurements; these sources would not be reported by the “official” WISE pipeline and will not appear in the WISE catalog, yet they can be highly informative for some scientific questions. In addition, these small-signal measurements can be used in stacking analyses at the catalog level. The forced photometry approach has the advantage that we measure a consistent set of sources between SDSS and WISE, taking advantage of the resolution and depth of the SDSS images to interpret the WISE images; objects that are resolved in SDSS but blended together in WISE still have accurate measurements in our photometry. Our results, and the code used to produce them, are publicly available at http://unwise.me.« less

VLBA SURVEYS OF OH MASERS IN STAR-FORMING REGIONS. I. SATELLITE LINES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruiz-Velasco, A. E.; Felli, D.; Migenes, V.

2016-05-10

Using the Very Long Baseline Array we performed a high-resolution OH maser survey in Galactic star-forming regions (SFRs). We observed all the ground state spectral lines: the main lines at 1665 and 1667 MHz and the satellite lines at 1612 and 1720 MHz. Due to the exceptionality of finding satellite lines in SFRs, we will focus our discussion on those lines. In our sample of 41 OH maser sources, five (12%) showed the 1612 MHz line and ten (24%) showed the 1720 MHz line, with only one source showing both lines. We find that 1720 MHz emission is correlated withmore » the presence of H ii regions, suggesting that this emission could be used to diagnose or trace high-mass star formation. We include an analysis of the possible mechanisms that could be causing this correlation as well as assessing the possible relationships between lines in our sample. In particular, the presence of magnetic fields seems to play an important role as we found Zeeman splitting in four of our sources (W75 N, W3(OH), W51 and NGC 7538). Our results have implications for current understanding of the formation of high-mass stars as well as on the masing processes present in SFRs.« less

Inertial confinement fusion method producing line source radiation fluence

DOEpatents

Rose, Ronald P.

1984-01-01

An inertial confinement fusion method in which target pellets are imploded in sequence by laser light beams or other energy beams at an implosion site which is variable between pellet implosions along a line. The effect of the variability in position of the implosion site along a line is to distribute the radiation fluence in surrounding reactor components as a line source of radiation would do, thereby permitting the utilization of cylindrical geometry in the design of the reactor and internal components.

Assessment of bacteriological quality of drinking water from various sources in Amritsar district of northern India.

PubMed

Malhotra, Sita; Sidhu, Shailpreet K; Devi, Pushpa

2015-08-29

Safe water is a precondition for health and development and is a basic human right, yet it is still denied to hundreds of millions of people throughout the developing world. Water-related diseases caused by insufficient safe water supplies, coupled with poor sanitation and hygiene, cause 3.4 million deaths a year, mostly in children. The present study was conducted on 1,317 drinking water samples from various water sources in Amritsar district in northern India. All the samples were analyzed to assess bacteriological quality of water for presumptive coliform count by the multiple tube test. A total of 42.9% (565/1,317) samples from various sources were found to be unfit for human consumption. Of the total 565 unsatisfactory samples, 253 were from submersible pumps, 197 were from taps of piped supply (domestic/public), 79 were from hand pumps, and 36 were from various other sources A significantly high level of contamination was observed in samples collected from submersible pumps (47.6%) and water tanks (47.3%), as these sources of water are more exposed and liable to contamination. Despite continuous efforts by the government, civil society, and the international community, over a billion people still do not have access to improved water resources. Bacteriological assessment of all sources of drinking should be planned and conducted on regular basis to prevent waterborne dissemination of diseases.

Hydrogen transmission/storage with a metal hydride/organic slurry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Breault, R.W.; Rolfe, J.; McClaine, A.

1998-08-01

Thermo Power Corporation has developed a new approach for the production, transmission, and storage of hydrogen. In this approach, a chemical hydride slurry is used as the hydrogen carrier and storage media. The slurry protects the hydride from unanticipated contact with moisture in the air and makes the hydride pumpable. At the point of storage and use, a chemical hydride/water reaction is used to produce high-purity hydrogen. An essential feature of this approach is the recovery and recycle of the spent hydride at centralized processing plants, resulting in an overall low cost for hydrogen. This approach has two clear benefits:more » it greatly improves energy transmission and storage characteristics of hydrogen as a fuel, and it produces the hydrogen carrier efficiently and economically from a low cost carbon source. The preliminary economic analysis of the process indicates that hydrogen can be produced for $3.85 per million Btu based on a carbon cost of $1.42 per million Btu and a plant sized to serve a million cars per day. This compares to current costs of approximately $9.00 per million Btu to produce hydrogen from $3.00 per million Btu natural gas, and $25 per million Btu to produce hydrogen by electrolysis from $0.05 per Kwh electricity. The present standard for production of hydrogen from renewable energy is photovoltaic-electrolysis at $100 to $150 per million Btu.« less

Search for cosmic ray sources using muons detected by the MACRO experiment

NASA Astrophysics Data System (ADS)

Ambrosio, M.; Antolini, R.; Auriemma, G.; Bakari, D.; Baldini, A.; Barbarino, G. C.; Barish, B. C.; Battistoni, G.; Becherini, Y.; Bellotti, R.; Bemporad, C.; Bernardini, P.; Bilokon, H.; Bloise, C.; Bower, C.; Brigida, M.; Bussino, S.; Cafagna, F.; Calicchio, M.; Campana, D.; Carboni, M.; Caruso, R.; Cecchini, S.; Cei, F.; Chiarella, V.; Choudhary, B. C.; Coutu, S.; Cozzi, M.; de Cataldo, G.; Dekhissi, H.; de Marzo, C.; de Mitri, I.; Derkaoui, J.; de Vincenzi, M.; di Credico, A.; Erriquez, O.; Favuzzi, C.; Forti, C.; Fusco, P.; Giacomelli, G.; Giannini, G.; Giglietto, N.; Giorgini, M.; Grassi, M.; Grillo, A.; Guarino, F.; Gustavino, C.; Habig, A.; Hanson, K.; Heinz, R.; Iarocci, E.; Katsavounidis, E.; Katsavounidis, I.; Kearns, E.; Kim, H.; Kyriazopoulou, S.; Lamanna, E.; Lane, C.; Levin, D. S.; Lipari, P.; Longley, N. P.; Longo, M. J.; Loparco, F.; Maaroufi, F.; Mancarella, G.; Mandrioli, G.; Margiotta, A.; Marini, A.; Martello, D.; Marzari-Chiesa, A.; Mazziotta, M. N.; Michael, D. G.; Monacelli, P.; Montaruli, T.; Monteno, M.; Mufson, S.; Musser, J.; Nicolò, D.; Nolty, R.; Orth, C.; Osteria, G.; Palamara, O.; Patera, V.; Patrizii, L.; Pazzi, R.; Peck, C. W.; Perrone, L.; Petrera, S.; Pistilli, P.; Popa, V.; Rainò, A.; Reynoldson, J.; Ronga, F.; Rrhioua, A.; Satriano, C.; Scapparone, E.; Scholberg, K.; Sciubba, A.; Serra, P.; Sioli, M.; Sirri, G.; Sitta, M.; Spinelli, P.; Spinetti, M.; Spurio, M.; Steinberg, R.; Stone, J. L.; Sulak, L. R.; Surdo, A.; Tarlè, G.; Togo, V.; Vakili, M.; Walter, C. W.; Webb, R.

2003-03-01

The MACRO underground detector at Gran Sasso Laboratory recorded 60 million secondary cosmic ray muons from February 1989 until December 2000. Different techniques were used to analyze this sample in search for density excesses from astrophysical point-like sources. No evidence for DC excesses for any source in an all-sky survey is reported. In addition, searches for muon excess correlated with the known binary periods of Cygnus X-3 and Hercules X-1, and searches for statistically significant bursting episodes from known γ-ray sources are also proved negative.

Ultraviolet Changes of the Central Source and the Very Nearby Ejecta

NASA Technical Reports Server (NTRS)

Gull, Theodore R.; Nielsen, Krister; Vierira, Gladys; Hillier, John; Walborn, Nolan; Davidson, Kris

2004-01-01

We utilized the high spatial and high spectral resolution of the HST/STIS MAMA echelle modes in the ultraviolet (0.025 inch spatial resolution and 30,000 to 120,000 spectral resolving power) to view changes in and around Eta Carinae before and after the X-Ray drop which occurred on June 29, 2003 (M. Corcoran, IAUC 8160). Major changes in the spectra of the Central Source and nearby nebulosities occurred between June 22 and July 5. Visibility of the Central Source dropped, especially between 1175 and 1350 Angstroms, but not uniformly throughout the ultraviolet. This fading is likely due to multiple line absorptions both in the source and in the intervening ejecta. Nebular emission of Si III] and Fe III, located 0.09 sec. to the west, disappeared. By July 29, a bright feature extending up to 0.071 sec. east of the Central Source became prominent in broad emission lines near 2500 Angstroms, but was not noticeable longward of 2900 Angstroms. ACS/HRC imagery and STIS CCD spectra taken concurrently are being examined for larger scale changes. Numerous narrow velocity components between -146 and -585 kilometers per second were identified in spectra before the minimum. New components appeared primarily in Fe II absorption lines with velocities between -170 and -380 kilometers per second. While the lines of the -513 kilometers per second component did not change, most lines of the -146 kilometers per second component changed considerably. Lines originating from high energy levels diminished or disappeared, while lines originating from lower energy levels strengthened. Strong absorption lines of Ti II, not present before the X-Ray drop, appeared within seven days, but disappeared by July 29. Further analysis of these unprecedented data will provide significant new information about the structure of Eta Carinae and its periodic variations.

Evaluation of maturity group III soybean lines for resistance to purple seed stain in Mississippi, 2010

USDA-ARS?s Scientific Manuscript database

Purple seed stain (PSS) of soybean is an important disease caused by Cercospora kikuchii. PSS reduces seed quality and market grade, affects seed germination and vigor, and has been reported wherever soybeans are grown worldwide. In 2009, PSS caused 6.4 million bushels of yield losses in 16 southern...

Evaluation of maturity group IV soybean lines for resistance to purple seed stains in Mississippi 2010

USDA-ARS?s Scientific Manuscript database

Purple seed stain (PSS) of soybean is an important disease caused by Cercospora kikuchii. PSS reduces seed quality and market grade, affects seed germination and vigor, and has been reported wherever soybeans are grown worldwide. In 2009, PSS caused 6.4 million bushels of yield losses in 16 southern...

Top 10 Research Questions Related to Physical Activity and Multiple Sclerosis

ERIC Educational Resources Information Center

Motl, Robert W.; Learmonth, Yvonne C.; Pilutti, Lara A.; Gappmaier, Eduard; Coote, Susan

2015-01-01

An estimated 2.5 million people worldwide are living with multiple sclerosis (MS), and this disease may be increasing in prevalence. MS is a disease of the central nervous system that is associated with heterogeneous symptoms and functional consequences, and the current first-line disease-modifying therapies often become ineffective later in the…

Discovering the "-Ologies" on the Jurassic Coast

ERIC Educational Resources Information Center

Peacock, Alan

2007-01-01

The Jurassic Coast is Britain's only natural World Heritage site, a tangible time-line that takes one through 185 million years of history in 95 miles of coast. It provides individuals with a world-famous educational resource and an unrivalled outdoor classroom that has played a key role in the study of earth sciences. The author is keen to ignite…

Libert-E Motor

ERIC Educational Resources Information Center

Sieloff, Susan F.; Kinnunen, Raymond; Chevarley, Joseph

2011-01-01

Kei Yun Wong has big dreams. She has been entrusted with the United States launch of Libert-E Motor, a new line of Chinese-manufactured electric scooters. With only $750,000 of her original budget of $3 million left, she needs to make sure that the launch succeeds, as it represents the initial step in her desire to create the first Chinese global…

Outside the Lines and beyond the Classroom: African American Football Student-Athletes' Experiences with Race in Academia

ERIC Educational Resources Information Center

Conroy, Carissa Marie

2016-01-01

Intercollegiate athletics are a multi-million-dollar business on which many universities strive to become dependent for economic profits and marketing leverage. The increased commercialization and revenues of collegiate sports have drawn attention to the overall college experiences of student-athletes, specifically those in revenue generating…

A New and Improved Rainbow Trout (Oncorhynchus mykiss) Reference Genome Assembly

USDA-ARS?s Scientific Manuscript database

In an effort to improve the rainbow trout reference genome assembly, we re-sequenced the doubled-haploid Swanson line using the longest available reads from the Illumina technology; generating over 510 million paired-end shotgun reads (2x260nt), and 1 billion mate-pair reads (2x160nt) from four sequ...

JPRS Report, Telecommunications.

DTIC Science & Technology

1989-03-24

3 LATIN AMERICA MEXICO Ericsson Plans $20 Million Investment in 1989 [ Mexico City UNOMASUNO, 1 Feb 89] ............... 4 NEAR EAST...Telephone System for Azores [Lisbon DIARIO DE NOTICIAS ECONOMIA , 30 Jan 89] ........................................................... 25 UNITED...aid in Bloc. JPRS-TTP-89-004 24 March 1989 LATIN AMERICA 4 MEXICO This contract will provide Mexico with over 2 milion AXE-equivalent lines, thus

Rethinking the Role of the Automobile. Worldwatch Paper No. 84.

ERIC Educational Resources Information Center

Renner, Michael

In 1987, a record 126,000 automobiles rolled off assembly lines each working day, and close to 400 million vehicles are used on the world's roads today. Prior to the 1970s the automobile's utility and sustainability were hardly questioned. A decade of oil price increases and worries about future fuel availability slowed automobile use somewhat,…

Power Converters Secure Electronics in Harsh Environments

NASA Technical Reports Server (NTRS)

2013-01-01

In order to harden power converters for the rigors of space, NASA awarded multiple SBIR contracts to Blacksburg, Virginia-based VPT Inc. The resulting hybrid DC-DC converters have proven valuable in aerospace applications, and as a result the company has generated millions in revenue from the product line and created four high-tech jobs to handle production.

Millions in cash in your hospital halls. Calculating the cash value of employee engagement, Part II.

PubMed

Simon, Matthew

2003-01-01

Quality of care and the bottom line are often seen as trade-offs. But this can be a false dichotomy. As we shall see, many of the factors impacted by employee engagement--a term that encompasses trust, loyalty, motivation and cooperative spirit--contribute to both quality of care and financial performance.

Gold in placer deposits

USGS Publications Warehouse

Yeend, Warren; Shawe, Daniel R.; Wier, Kenneth L.

1989-01-01

Man most likely first obtained gold from placer deposits, more than 6,000 years ago. Placers account for more than two-thirds of the total world gold supply, and roughly half of that mined in the States of California, Alaska, Montana, and Idaho.Placer deposits result from weathering and release of gold from lode deposits, transportation of the gold, and concentration of the gold dominantly in stream gravels. Unless preserved by burial, a placer subsequently may be eroded, and either dispersed or reconcentrated.California has produced more than 40 million troy ounces of gold from placers, both modern and fossil (Tertiary). The source of the great bulk of the gold is numerous quartz veins and mineralized zones of the Mother Lode and related systems in the western Sierra Nevada region. The gold-bearing lodes were emplaced in Carboniferous and Jurassic metamorphic rocks intruded by small bodies of Jurassic and Cretaceous igneous rocks. Mineralization occurred probably in Late Cretaceous time. Significant amounts of placer gold also were mined along the Salmon and Trinity Rivers in northern California. Source of the gold is lode deposits in Paleozoic and Mesozoic metamorphic rocks that were intruded by Mesozoic igneous rocks.Alaska has produced roughly 21 million ounces of gold from placer deposits. Most (about 13 million ounces) has come from the interior region, including 7,600,000 ounces from the Fairbanks district and 1,300,000 ounces from the Iditarod district. Lode sources are believed to be mostly quartz veins in Precambrian or Paleozoic metamorphic rocks intruded by small igneous bodies near Fairbanks, and shear zones in Tertiary(?) quartz monzonite stocks at Iditarod. The Seward Peninsula has produced more than 6 million ounces of placer gold, including about 4,000,000 ounces from the Nome district. Most of the gold was derived from raised beach deposits. Source of the gold probably is Tertiary-mineralized faults and joints in metamorphic rocks of late Precambrian age.The Helena-Last Chance district, Montana, produced nearly 1 million ounces of gold from placers that were derived from lode deposits in the contact zones of the Cretaceous Boulder batholith granitic rocks intruded into upper Precambrian, Paleozoic, and Mesozoic sedimentary rocks. The Virginia City-Alder Gulch district, Montana, produced more than 2,600,000 ounces of gold, nearly all from placer deposits derived from quartz veins of uncertain age in Archean gneisses and schists. The Boise basin district, Idaho, produced about 2,300,000 ounces of gold, mostly derived from quartz veins in quartz monzonite of the Cretaceous Idaho batholith.

SpIES: The Spitzer IRAC Equatorial Survey

NASA Technical Reports Server (NTRS)

Timlin, John D.; Ross, Nicholas P.; Richards, Gordon, T.; Lacy, Mark; Ryan, Erin L.; Stone, Robert B.; Bauer, Franz, E.; Brandt, W. N.; Fan, Xiaohui; Glikman, Eilat;

Body and Surface Wave Modeling of Observed Seismic Events. Part 2.

DTIC Science & Technology

1987-05-12

is based on expand - ing the complete three dimensional solution of the wave equation expressed in cylindrical S coordinates in an asymptotic form which...using line source (2-D) theory. It is based on expand - ing the complete three dimensional solution of the wave equation expressed in cylindrical...generating synthetic point-source seismograms for shear dislocation sources using line source (2-D) theory. It is based on expanding the complete three

Runoff phosphorus in a small rotationally-grazed pasture in Georgia with no history of broiler litter application

USDA-ARS?s Scientific Manuscript database

Pastures are sources of phosphorus (P) into water sources and can contribute to eutrophication and impairment. Close to 4 million ha of land in the Southern Coastal Plain and the Southern Piedmont in eastern USA is used for pasture and hay production. We present an 11-yr (1999 to 2009) of dissolved ...

Influence of a source line position on results of EM observations applied to the diagnostics of underground heating system pipelines in urban area

NASA Astrophysics Data System (ADS)

Vetrov, A.

2009-05-01

The condition of underground constructions, communication and supply systems in the cities has to be periodically monitored and controlled in order to prevent their breakage, which can result in serious accident, especially in urban area. The most risk of damage have the underground construction made of steal such as pipelines widely used for water, gas and heat supply. To ensure the pipeline survivability it is necessary to carry out the operative and inexpensive control of pipelines condition. Induced electromagnetic methods of geophysics can be applied to provide such diagnostics. The highly developed surface in urbane area is one of cause hampering the realization of electromagnetic methods of diagnostics. The main problem is in finding of an appropriate place for the source line and electrodes on a limited surface area and their optimal position relative to the observation path to minimize their influence on observed data. Author made a number of experiments of an underground heating system pipeline diagnostics using different position of the source line and electrodes. The experiments were made on a 200 meters section over 2 meters deep pipeline. The admissible length of the source line and angle between the source line and the observation path were determined. The minimal length of the source line for the experiment conditions and accuracy made 30 meters, the maximum admissible angle departure from the perpendicular position made 30 degrees. The work was undertaken in cooperation with diagnostics company DIsSO, Saint-Petersburg, Russia.

Bubble-induced skin-friction drag reduction and the abrupt transition to air-layer drag reduction

NASA Astrophysics Data System (ADS)

Elbing, Brian R.; Winkel, Eric S.; Lay, Keary A.; Ceccio, Steven L.; Dowling, David R.; Perlin, Marc

To investigate the phenomena of skin-friction drag reduction in a turbulent boundary layer (TBL) at large scales and high Reynolds numbers, a set of experiments has been conducted at the US Navy's William B. Morgan Large Cavitation Channel (LCC). Drag reduction was achieved by injecting gas (air) from a line source through the wall of a nearly zero-pressure-gradient TBL that formed on a flat-plate test model that was either hydraulically smooth or fully rough. Two distinct drag-reduction phenomena were investigated; bubble drag reduction (BDR) and air-layer drag reduction (ALDR).The streamwise distribution of skin-friction drag reduction was monitored with six skin-friction balances at downstream-distance-based Reynolds numbers to 220 million and at test speeds to 20.0msinitial zone1. These results indicated that there are three distinct regions associated with drag reduction with air injection: Region I, BDR; Region II, transition between BDR and ALDR; and Region III, ALDR. In addition, once ALDR was established: friction drag reduction in excess of 80% was observed over the entire smooth model for speeds to 15.3ms1 with the surface fully roughened (though approximately 50% greater volumetric air flux was required); and ALDR was sensitive to the inflow conditions. The sensitivity to the inflow conditions can be mitigated by employing a small faired step (10mm height in the experiment) that helps to create a fixed separation line.

Line-scanning, stage scanning confocal microscope

NASA Astrophysics Data System (ADS)

Carucci, John A.; Stevenson, Mary; Gareau, Daniel

2016-03-01

We created a line-scanning, stage scanning confocal microscope as part of a new procedure: video assisted micrographic surgery (VAMS). The need for rapid pathological assessment of the tissue on the surface of skin excisions very large since there are 3.5 million new skin cancers diagnosed annually in the United States. The new design presented here is a confocal microscope without any scanning optics. Instead, a line is focused in space and the sample, which is flattened, is physically translated such that the line scans across its face in a direction perpendicular to the line its self. The line is 6mm long and the stage is capable of scanning 50 mm, hence the field of view is quite large. The theoretical diffraction-limited resolution is 0.7um lateral and 3.7um axial. However, in this preliminary report, we present initial results that are a factor of 5-7 poorer in resolution. The results are encouraging because they demonstrate that the linear array detector measures sufficient signal from fluorescently labeled tissue and also demonstrate the large field of view achievable with VAMS.

A magnified young galaxy from about 500 million years after the Big Bang.

PubMed

Zheng, Wei; Postman, Marc; Zitrin, Adi; Moustakas, John; Shu, Xinwen; Jouvel, Stephanie; Høst, Ole; Molino, Alberto; Bradley, Larry; Coe, Dan; Moustakas, Leonidas A; Carrasco, Mauricio; Ford, Holland; Benítez, Narciso; Lauer, Tod R; Seitz, Stella; Bouwens, Rychard; Koekemoer, Anton; Medezinski, Elinor; Bartelmann, Matthias; Broadhurst, Tom; Donahue, Megan; Grillo, Claudio; Infante, Leopoldo; Jha, Saurabh W; Kelson, Daniel D; Lahav, Ofer; Lemze, Doron; Melchior, Peter; Meneghetti, Massimo; Merten, Julian; Nonino, Mario; Ogaz, Sara; Rosati, Piero; Umetsu, Keiichi; van der Wel, Arjen

2012-09-20

Re-ionization of the intergalactic medium occurred in the early Universe at redshift z ≈ 6-11, following the formation of the first generation of stars. Those young galaxies (where the bulk of stars formed) at a cosmic age of less than about 500 million years (z ≲ 10) remain largely unexplored because they are at or beyond the sensitivity limits of existing large telescopes. Understanding the properties of these galaxies is critical to identifying the source of the radiation that re-ionized the intergalactic medium. Gravitational lensing by galaxy clusters allows the detection of high-redshift galaxies fainter than what otherwise could be found in the deepest images of the sky. Here we report multiband observations of the cluster MACS J1149+2223 that have revealed (with high probability) a gravitationally magnified galaxy from the early Universe, at a redshift of z = 9.6 ± 0.2 (that is, a cosmic age of 490 ± 15 million years, or 3.6 per cent of the age of the Universe). We estimate that it formed less than 200 million years after the Big Bang (at the 95 per cent confidence level), implying a formation redshift of ≲14. Given the small sky area that our observations cover, faint galaxies seem to be abundant at such a young cosmic age, suggesting that they may be the dominant source for the early re-ionization of the intergalactic medium.

Understanding large-scale, long-term larval connectivity patterns: The case of the Northern Line Islands in the Central Pacific Ocean

PubMed Central

Mari, Lorenzo; Bonaventura, Luca; Storto, Andrea; Melià, Paco; Gatto, Marino; Masina, Simona

2017-01-01

Protecting key hotspots of marine biodiversity is essential to maintain ecosystem services at large spatial scales. Protected areas serve not only as sources of propagules colonizing other habitats, but also as receptors, thus acting as protected nurseries. To quantify the geographical extent and the temporal persistence of ecological benefits resulting from protection, we investigate larval connectivity within a remote archipelago, characterized by a strong spatial gradient of human impact from pristine to heavily exploited: the Northern Line Islands (NLIs), including part of the Pacific Remote Islands Marine National Monument (PRI-MNM). Larvae are described as passive Lagrangian particles transported by oceanic currents obtained from a oceanographic reanalysis. We compare different simulation schemes and compute connectivity measures (larval exchange probabilities and minimum/average larval dispersal distances from target islands). To explore the role of PRI-MNM in protecting marine organisms with pelagic larval stages, we drive millions of individual-based simulations for various Pelagic Larval Durations (PLDs), in all release seasons, and over a two-decades time horizon (1991–2010). We find that connectivity in the NLIs is spatially asymmetric and displays significant intra- and inter-annual variations. The islands belonging to PRI-MNM act more as sinks than sources of larvae, and connectivity is higher during the winter-spring period. In multi-annual analyses, yearly averaged southward connectivity significantly and negatively correlates with climatological anomalies (El Niño). This points out a possible system fragility and susceptibility to global warming. Quantitative assessments of large-scale, long-term marine connectivity patterns help understand region-specific, ecologically relevant interactions between islands. This is fundamental for devising scientifically-based protection strategies, which must be space- and time-varying to cope with the challenges posed by the concurrent pressures of human exploitation and global climate change. PMID:28809937

Understanding large-scale, long-term larval connectivity patterns: The case of the Northern Line Islands in the Central Pacific Ocean.

PubMed

Mari, Lorenzo; Bonaventura, Luca; Storto, Andrea; Melià, Paco; Gatto, Marino; Masina, Simona; Casagrandi, Renato

2017-01-01

Protecting key hotspots of marine biodiversity is essential to maintain ecosystem services at large spatial scales. Protected areas serve not only as sources of propagules colonizing other habitats, but also as receptors, thus acting as protected nurseries. To quantify the geographical extent and the temporal persistence of ecological benefits resulting from protection, we investigate larval connectivity within a remote archipelago, characterized by a strong spatial gradient of human impact from pristine to heavily exploited: the Northern Line Islands (NLIs), including part of the Pacific Remote Islands Marine National Monument (PRI-MNM). Larvae are described as passive Lagrangian particles transported by oceanic currents obtained from a oceanographic reanalysis. We compare different simulation schemes and compute connectivity measures (larval exchange probabilities and minimum/average larval dispersal distances from target islands). To explore the role of PRI-MNM in protecting marine organisms with pelagic larval stages, we drive millions of individual-based simulations for various Pelagic Larval Durations (PLDs), in all release seasons, and over a two-decades time horizon (1991-2010). We find that connectivity in the NLIs is spatially asymmetric and displays significant intra- and inter-annual variations. The islands belonging to PRI-MNM act more as sinks than sources of larvae, and connectivity is higher during the winter-spring period. In multi-annual analyses, yearly averaged southward connectivity significantly and negatively correlates with climatological anomalies (El Niño). This points out a possible system fragility and susceptibility to global warming. Quantitative assessments of large-scale, long-term marine connectivity patterns help understand region-specific, ecologically relevant interactions between islands. This is fundamental for devising scientifically-based protection strategies, which must be space- and time-varying to cope with the challenges posed by the concurrent pressures of human exploitation and global climate change.

High spectral resolution observations of fluorescent molecular hydrogen in molecular clouds

NASA Technical Reports Server (NTRS)

Burton, Michael G.; Geballe, T. R.; Brand, P. W. J. L.; Moorhouse, A.

1990-01-01

The 1-0 S(1) line of molecular hydrogen has been observed at high spectral resolution in several sources where the emission was suspected of being fluorescent. In NGC 2023, the Orion Bar, and Parsamyan 18, the S(1) line is unresolved, and the line center close to the rest velocity of the ambient molecular cloud. Such behavior is expected for UV-excited line emission. The H2 line widths in molecular clouds thus can serve as diagnostic for shocked and UV-excitation mechanisms. If the lines are broader than several km/s or velocity shifts are observed across a source it is likely that shocks are responsible for the excitation of the gas.

40 CFR 421.284 - Standards of performance for new sources.

Code of Federal Regulations, 2010 CFR

2010-07-01

... for monthly average mg/kg (pounds per million pounds) of tantalum powder produced from leaching Copper... all times. (e) Leaching wet air pollution control. NSPS for the Secondary Tantalum Subcategory...

40 CFR 421.284 - Standards of performance for new sources.

Code of Federal Regulations, 2013 CFR

2013-07-01

... for monthly average mg/kg (pounds per million pounds) of tantalum powder produced from leaching Copper... all times. (e) Leaching wet air pollution control. NSPS for the Secondary Tantalum Subcategory...

40 CFR 421.284 - Standards of performance for new sources.

Code of Federal Regulations, 2014 CFR

2014-07-01

... for monthly average mg/kg (pounds per million pounds) of tantalum powder produced from leaching Copper... all times. (e) Leaching wet air pollution control. NSPS for the Secondary Tantalum Subcategory...

40 CFR 421.284 - Standards of performance for new sources.

Code of Federal Regulations, 2012 CFR

2012-07-01

... for monthly average mg/kg (pounds per million pounds) of tantalum powder produced from leaching Copper... all times. (e) Leaching wet air pollution control. NSPS for the Secondary Tantalum Subcategory...

40 CFR 421.284 - Standards of performance for new sources.

Code of Federal Regulations, 2011 CFR

2011-07-01

... for monthly average mg/kg (pounds per million pounds) of tantalum powder produced from leaching Copper... all times. (e) Leaching wet air pollution control. NSPS for the Secondary Tantalum Subcategory...

Lab Tracker and Copper Calculator

MedlinePlus

... Wilson's disease patients? If the water is over 0.1 ppm (parts per million) (which is 0.1 mg/L), I recommend an alternative source. While 0.1 ppm isn't particularly hazardous, it indicates that ...

Making sense of rocket science - NASA's knowledge management program

NASA Technical Reports Server (NTRS)

Holm, J.

2002-01-01

The National Aeronautics and Space Administration (NASA) has launched a range of KM activities - from deploying intelligent 'know-bots' across millions of electronic sources to ensuring tacit knowledge is transferred across generations.