Sample records for minimum activity epoch

  1. Grand minima of solar activity and sociodynamics of culture

    NASA Astrophysics Data System (ADS)

    Vladimirsky, B. M.

    2012-12-01

    Indices of creative productivity introduced by C. Murrey were used to verify S. Ertel's conclusion about a global increase in creative productivity during the prolonged minimum of solar activity in 1640-1710. It was found that these indices for mathematicians, philosophers, and scientists increase in the Maunder era by factor of 1.6 in comparison with intervals of the same length before and after the minimum. A similar effect was obtained for mathematicians and philosophers for five earlier equitype minima in total (an increase by a factor of 1.9). The regularity that is revealed is confirmed by the fact that the most important achievements of high-ranking mathematicians and philosophers during the whole time period (2300 years) considered in this study fall on epochs of reduced levels of solar activity. The rise in the probability of the generation of rational ideas during grand minima is reflected also in the fact that they precede the appearance of written language and farming. Ultra-low-frequency electromagnetic fields appear to serve as a physical agent stimulating the activity of the brain's left hemisphere during the epochs of minima.

  2. The electrophysiological "delayed effect" of focal interictal epileptiform discharges. A low resolution electromagnetic tomography (LORETA) study.

    PubMed

    Clemens, Béla; Piros, Pálma; Bessenyei, Mónika; Varga, Edit; Puskás, Szilvia; Fekete, István

    2009-08-01

    Collating the findings regarding the role of focal interictal epileptiform discharges (IEDs) on CNS functions raises the possibility that IEDs might have negative impact that outlasts the duration of the spike-and-wave complexes. The aim of this study was the electrophysiological demonstration of the "delayed effect" of the IEDs. 19-channel, linked-ears referenced, digital waking EEG records of 11 children (aged 6-14 years, eight with idiopathic, three with cryptogenic focal epilepsy, showing a single spike focus) were retrospectively selected from our database. A minimum of 20 (preferably, 30), 2-s epochs containing a single focal spike-and-wave complex were selected (Spike epochs). Thereafter, Postspike-1 (Ps1), Postspike-2 (Ps2) and Postspike-3 (Ps3) epochs were selected, representing the first and second seconds (Ps1), the third and fourth seconds (Ps2) and the fifth and sixth seconds (Ps3) after the Spike epoch, respectively. Interspike epochs (Is) were selected at a distance at least 10s after the Spike epoch. Individual analysis: the frequency of interest (FOI=the individual frequency of the wave component of the IEDs), and the region of interest (ROI=the site of the IEDs) were identified by reading the raw EEG waveform and the instant power spectrum. Very narrow band LORETA (low resolution electromagnetic tomography) analysis at the FOI and ROI was carried out. Age-adjusted, Z-transformed LORETA "activity" (=current source density, amperes/meters squared) was compared in the Spike, Ps1, Ps2, Ps3 and Is epochs. the greatest (uppermost pathological) Z-scores and the greatest spatial extension of the LORETA-abnormality were always found in the Spike epochs, followed by the gradual decrease of activity in terms of severity and spatial extension in the Ps1, Ps2, Ps3 epochs. The lowest (baseline) level and extension of the abnormality was found in the Is epochs. Group analysis: average values of activity across the patients were computed for the temporal decrease of the abnormality. a clear tendency for the decrease of abnormality was demonstrated. the "delayed effect" of the IEDs was demonstrated electrophysiologically and quantified. The method may be utilized in the individual assessment of the effect of IEDs on cortical activity, the degree and temporo-spatial extension of the abnormality.

  3. Climatology of GW-TIDs in the magnetic equatorial upper thermosphere over India

    NASA Astrophysics Data System (ADS)

    Manju, G.; Aswathy, R. P.

    2017-11-01

    An analysis of Gravity wave induced travelling ionospheric disturbances (GW-TIDs) in the thermosphere during high and low solar epochs is undertaken using ionosonde data at Trivandrum (8.50N, 770E). Wavelet analysis is performed on the temporal variations of foF2 and the amplitudes of waves present in two period bands of (0.5-1.5) h and (2-4) h are extracted. The real height profiles are generated at 15 min internal for the whole day (for sample days) during high and low solar activity years. The study reveals that the GW-TID activity is significantly greater for solar minimum compared to solar maximum for the period 8.5-17.5 h. Diurnally the GW-TID activity in the (2-4) h period band peaks in the post sunset hours for both high and low solar epochs. For the 0.5-1.5 h period band, the diurnal maximum in GW-TID is occurring in the post sunset hours for high solar epoch while it occurs in the morning hours around 10 h LT for low solar epoch. Seasonally the day time GW-TID activity maximizes (minimizes) for winter (vernal equinox). The post sunset time GW-TID maximizes (minimizes) either for summer/winter (vernal equinox). The other interesting observation is the anti correlation of GW-TID in upper thermosphere with solar activity for day time and the correlation of the same with solar activity in the post sunset hours. The present results for daytime are in agreement with the equatorial daytime GW-TID behaviour reported from CHAMP satellite observations. The GW-TID activity during post sunset time for equatorial region upper thermosphere has not been reported so far.

  4. Could a Hexagonal Sunspot Have Been Observed During the Maunder Minimum?

    NASA Astrophysics Data System (ADS)

    Carrasco, V. M. S.; Vaquero, J. M.; Gallego, M. C.

    2018-03-01

    The Maunder Minimum is the period between 1645 and 1715. Its main characteristic is abnormally low and prolonged solar activity. However, some authors have doubted the low level of solar activity during that period by questioning the accuracy and objectivity of the observers. This work presents a particular case of a sunspot observed during the Maunder Minimum with an unusual shape of its umbra and penumbra: a hexagon. This sunspot was observed by Cassini in November 1676, just at the core of the Maunder Minimum. This historical observation is compared with a twin case that occurred recently in May 2016. The conclusion reached is that Cassini's record is another example of the good quality of the observations that were made during the Maunder Minimum, showing the meticulousness of the astronomers of that epoch. This sunspot observation made by Cassini does not support the conclusions of Zolotova and Ponyavin ( Astrophys. J. 800, 42, 2015) that professional astronomers in the seventeenth century only registered round sunspots. Finally, a discussion is given of the importance of this kind of unusual sunspot record for a better assessment of the true level of solar activity in the Maunder Minimum.

  5. Activity associated with the solar origin of coronal mass ejections

    NASA Technical Reports Server (NTRS)

    Webb, D. F.; Hundhausen, A. J.

    1987-01-01

    Solar coronal mass ejections (CMEs) observed in 1980 with the HAO Coronagraph/Polarimeter on the Solar Maximum Mission (SMM) satellite are compared with other forms of solar activity that might be physically related to the ejections. The solar phenomena checked and the method of association used were intentionally patterned after those of Munro et al.'s (1979) analysis of mass ejections observed with the Skylab coronagraph to facilitate comparison of the two epochs. Comparison of the results reveals that the types and degree of CME associations are similar near solar activity minimum and at maximum. For both epochs, most CMEs with associations had associated eruptive prominences, and the proportions of association of all types of activity were similar. A high percentage of association between SMM CMEs and X-ray long duration events is also found, in agreement with Skylab results. It is concluded that most CMEs are the result of the destabilization and eruption of a prominence and its overlying coronal structure, or of a magnetic structure capable of supporting a prominence.

  6. A study of the geomagnetic indices asymmetry based on the interplanetary magnetic field polarities

    NASA Astrophysics Data System (ADS)

    El-Borie, M. A.; El-Taher, A. M.; Aly, N. E.; Bishara, A. A.

    2018-05-01

    Data of geomagnetic indices ( aa, Kp, Ap, and Dst) recorded near 1 AU over the period 1967-2016, have been studied based on the asymmetry between the interplanetary magnetic field (IMF) directions above and below of the heliospheric current sheet (HCS). Our results led to the following conclusions: (i) Throughout the considered period, 31 random years (62%) showed apparent asymmetries between Toward (T) and Away (A) polarity days and 19 years (38%) exhibited nearly a symmetrical behavior. The days of A polarity predominated over the T polarity days by 4.3% during the positive magnetic polarity epoch (1991-1999). While the days of T polarity exceeded the days of A polarity by 5.8% during the negative magnetic polarity epoch (2001-2012). (ii) Considerable yearly North-South (N-S) asymmetries of geomagnetic indices observed throughout the considered period. (iii) The largest toward dominant peaks for aa and Ap indices occurred in 1995 near to minimum of solar activity. Moreover, the most substantial away dominant peaks for aa and Ap indices occurred in 2003 (during the descending phase of the solar cycle 23) and in 1991 (near the maximum of solar activity cycle) respectively. (iv) The N-S asymmetry of Kp index indicated a most significant away dominant peak occurred in 2003. (v) Four of the away dominant peaks of Dst index occurred at the maxima of solar activity in the years 1980, 1990, 2000, and 2013. The largest toward dominant peak occurred in 1991 (at the reversal of IMF polarity). (vi) The geomagnetic indices ( aa, Ap, and Kp) all have northern dominance during positive magnetic polarity epoch (1971-1979), while the asymmetries shifts to the southern solar hemisphere during negative magnetic polarity epoch (2001-2012).

  7. A Relationship Between the Solar Rotation and Activity Analysed by Tracing Sunspot Groups

    NASA Astrophysics Data System (ADS)

    Ruždjak, Domagoj; Brajša, Roman; Sudar, Davor; Skokić, Ivica; Poljančić Beljan, Ivana

    2017-12-01

    The sunspot position published in the data bases of the Greenwich Photoheliographic Results (GPR), the US Air Force Solar Optical Observing Network and National Oceanic and Atmospheric Administration (USAF/NOAA), and of the Debrecen Photoheliographic Data (DPD) in the period 1874 to 2016 were used to calculate yearly values of the solar differential-rotation parameters A and B. These differential-rotation parameters were compared with the solar-activity level. We found that the Sun rotates more differentially at the minimum than at the maximum of activity during the epoch 1977 - 2016. An inverse correlation between equatorial rotation and solar activity was found using the recently revised sunspot number. The secular decrease of the equatorial rotation rate that accompanies the increase in activity stopped in the last part of the twentieth century. It was noted that when a significant peak in equatorial rotation velocity is observed during activity minimum, the next maximum is weaker than the previous one.

  8. Influence of geomagnetic activity and atmospheric pressure on human arterial pressure during the solar cycle 24

    NASA Astrophysics Data System (ADS)

    Azcárate, T.; Mendoza, B.; Levi, J. R.

    2016-11-01

    We performed a study of the systolic (SBP) and diastolic (DBP) arterial blood pressure behavior under natural variables such as the atmospheric pressure (AtmP) and the horizontal geomagnetic field component (H). We worked with a sample of 304 healthy normotense volunteers, 152 men and 152 women, with ages between 18 and 84 years in Mexico City during the period 2008-2014, corresponding to the minimum, ascending and maximum phases of the solar cycle 24. The data was divided by gender, age and day/night cycle. We studied the time series using three methods: Correlations, bivariate and superposed epochs (within a window of three days around the day of occurrence of a geomagnetic storm) analysis, between the SBP and DBP and the natural variables (AtmP and H). The correlation analysis indicated correlation between the SBP and DBP and AtmP and H, being the largest during the night. Furthermore, the correlation and bivariate analysis showed that the largest correlations are between the SBP and DBP and the AtmP. The superposed epoch analysis found that the largest number of significant SBP and DBP changes occurred for women. Finally, the blood pressure changes are larger during the solar minimum and ascending solar cycle phases than during the solar maximum; the storms of the minimum were more intense than those of the maximum and this could be the reason of behavior of the blood pressure changes along the solar cycle.

  9. Latitude and Power Characteristics of Solar Activity at the End of the Maunder Minimum

    NASA Astrophysics Data System (ADS)

    Ivanov, V. G.; Miletsky, E. V.

    2017-12-01

    Two important sources of information about sunspots in the Maunder minimum are the Spörer catalog (Spörer, 1889) and observations of the Paris observatory (Ribes and Nesme-Ribes, 1993), which cover in total the last quarter of the 17th and the first two decades of the 18th century. These data, in particular, contain information about sunspot latitudes. As we showed in (Ivanov et al., 2011; Ivanov and Miletsky, 2016), dispersions of sunspot latitude distributions are tightly related to sunspot indices, and we can estimate the level of solar activity in the past using a method which is not based on direct calculation of sunspots and weakly affected by loss of observational data. The latitude distributions of sunspots in the time of transition from the Maunder minimum to the regular regime of solar activity proved to be wide enough. It gives evidences in favor of, first, not very low cycle no.-3 (1712-1723) with the Wolf number in maximum W = 100 ± 50, and, second, nonzero activity in the maximum of cycle no.-4 (1700-1711) W = 60 ± 45. Therefore, the latitude distributions in the end of the Maunder minimum are in better agreement with the traditional Wolf numbers and new revisited indices of activity SN and GN (Clette et al., 2014; Svalgaard and Schatten, 2016) than with the GSN (Hoyt and Schatten, 1998); the latter provide much lower level of activity in this epoch.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Pisin; Hsin, Po-Shen; Niu, Yuezhen, E-mail: pisinchen@phys.ntu.edu.tw, E-mail: r01222031@ntu.edu.tw, E-mail: yuezhenniu@gmail.com

    We investigate the entropy evolution in the early universe by computing the change of the entanglement entropy in Freedmann-Robertson-Walker quantum cosmology in the presence of particle horizon. The matter is modeled by a Chaplygin gas so as to provide a smooth interpolation between inflationary and radiation epochs, rendering the evolution of entropy from early time to late time trackable. We found that soon after the onset of the inflation, the total entanglement entropy rapidly decreases to a minimum. It then rises monotonically in the remainder of the inflation epoch as well as the radiation epoch. Our result is in qualitativemore » agreement with the area law of Ryu and Takayanagi including the logarithmic correction. We comment on the possible implication of our finding to the cosmological entropy problem.« less

  11. Effects of Varying Epoch Lengths, Wear Time Algorithms, and Activity Cut-Points on Estimates of Child Sedentary Behavior and Physical Activity from Accelerometer Data.

    PubMed

    Banda, Jorge A; Haydel, K Farish; Davila, Tania; Desai, Manisha; Bryson, Susan; Haskell, William L; Matheson, Donna; Robinson, Thomas N

    2016-01-01

    To examine the effects of accelerometer epoch lengths, wear time (WT) algorithms, and activity cut-points on estimates of WT, sedentary behavior (SB), and physical activity (PA). 268 7-11 year-olds with BMI ≥ 85th percentile for age and sex wore accelerometers on their right hips for 4-7 days. Data were processed and analyzed at epoch lengths of 1-, 5-, 10-, 15-, 30-, and 60-seconds. For each epoch length, WT minutes/day was determined using three common WT algorithms, and minutes/day and percent time spent in SB, light (LPA), moderate (MPA), and vigorous (VPA) PA were determined using five common activity cut-points. ANOVA tested differences in WT, SB, LPA, MPA, VPA, and MVPA when using the different epoch lengths, WT algorithms, and activity cut-points. WT minutes/day varied significantly by epoch length when using the NHANES WT algorithm (p < .0001), but did not vary significantly by epoch length when using the ≥ 20 minute consecutive zero or Choi WT algorithms. Minutes/day and percent time spent in SB, LPA, MPA, VPA, and MVPA varied significantly by epoch length for all sets of activity cut-points tested with all three WT algorithms (all p < .0001). Across all epoch lengths, minutes/day and percent time spent in SB, LPA, MPA, VPA, and MVPA also varied significantly across all sets of activity cut-points with all three WT algorithms (all p < .0001). The common practice of converting WT algorithms and activity cut-point definitions to match different epoch lengths may introduce significant errors. Estimates of SB and PA from studies that process and analyze data using different epoch lengths, WT algorithms, and/or activity cut-points are not comparable, potentially leading to very different results, interpretations, and conclusions, misleading research and public policy.

  12. Will Solar Cycles 25 and 26 Be Weaker than Cycle 24?

    NASA Astrophysics Data System (ADS)

    Javaraiah, J.

    2017-11-01

    The study of variations in solar activity is important for understanding the underlying mechanism of solar activity and for predicting the level of activity in view of the activity impact on space weather and global climate. Here we have used the amplitudes (the peak values of the 13-month smoothed international sunspot number) of Solar Cycles 1 - 24 to predict the relative amplitudes of the solar cycles during the rising phase of the upcoming Gleissberg cycle. We fitted a cosine function to the amplitudes and times of the solar cycles after subtracting a linear fit of the amplitudes. The best cosine fit shows overall properties (periods, maxima, minima, etc.) of Gleissberg cycles, but with large uncertainties. We obtain a pattern of the rising phase of the upcoming Gleissberg cycle, but there is considerable ambiguity. Using the epochs of violations of the Gnevyshev-Ohl rule (G-O rule) and the `tentative inverse G-O rule' of solar cycles during the period 1610 - 2015, and also using the epochs where the orbital angular momentum of the Sun is steeply decreased during the period 1600 - 2099, we infer that Solar Cycle 25 will be weaker than Cycle 24. Cycles 25 and 26 will have almost same strength, and their epochs are at the minimum between the current and upcoming Gleissberg cycles. In addition, Cycle 27 is expected to be stronger than Cycle 26 and weaker than Cycle 28, and Cycle 29 is expected to be stronger than both Cycles 28 and 30. The maximum of Cycle 29 is expected to represent the next Gleissberg maximum. Our analysis also suggests a much lower value (30 - 40) for the maximum amplitude of the upcoming Cycle 25.

  13. Variability of fractal dimension of solar radio flux

    NASA Astrophysics Data System (ADS)

    Bhatt, Hitaishi; Sharma, Som Kumar; Trivedi, Rupal; Vats, Hari Om

    2018-04-01

    In the present communication, the variation of the fractal dimension of solar radio flux is reported. Solar radio flux observations on a day to day basis at 410, 1415, 2695, 4995, and 8800 MHz are used in this study. The data were recorded at Learmonth Solar Observatory, Australia from 1988 to 2009 covering an epoch of two solar activity cycles (22 yr). The fractal dimension is calculated for the listed frequencies for this period. The fractal dimension, being a measure of randomness, represents variability of solar radio flux at shorter time-scales. The contour plot of fractal dimension on a grid of years versus radio frequency suggests high correlation with solar activity. Fractal dimension increases with increasing frequency suggests randomness increases towards the inner corona. This study also shows that the low frequency is more affected by solar activity (at low frequency fractal dimension difference between solar maximum and solar minimum is 0.42) whereas, the higher frequency is less affected by solar activity (here fractal dimension difference between solar maximum and solar minimum is 0.07). A good positive correlation is found between fractal dimension averaged over all frequencies and yearly averaged sunspot number (Pearson's coefficient is 0.87).

  14. Salt Kinematics and InSAR

    NASA Technical Reports Server (NTRS)

    Aftabi, Pedarm; Talbot, hristopher; Fielding, Eric

    2005-01-01

    As part of a long-term attempt to learn how the climatic and tectonic signal interact to shape a steady state mountain monitored displacement of a markers in SE termination and also near the summit of a small viscous salt fountain extruding onto the Central plateau of Iran. The marker displacements relate to the first InSAR interferograms of salt extrusion (980913 to 990620) calculated Earth tides, winds, air pressures and temperatures. In the first documented staking exercise, hammered wooden stakes vertically through the surgical marl (c. 1 Ocm deep) onto the top of crystalline salt. These stakes installed in an irregular array elongate E-W along the c.50 m high cliff marking the effective SE terminus of the glacier at Qum Kuh(Centra1 Iran) ,just to the E of a NE trending river cliff about 40 m high. We merely measured the distances between pairs of stakes with known azimuth about 2 m apart to calculate sub horizontal strain in a small part of Qum Kuh. Stakes moved and micro strains for up to 46 pairs of stakes (p strain= ((lengthl-length2)/1engthl) x 10-1) was calculated for each seven stake epochs and plotted against their azimuth on simplified array maps. The data fit well the sine curves cxpected of the maximum and minimum strain ellipses. The first documented stakes located on the SE where the InSAR image show -1 1 to 0 mm pink to purple, 0 to lOmm purple to blue, and show high activity of salt in low activity area of the InSAR image (980913 to 990620).Short term micro strains of stake tie lines record anisotropic expansions due to heating and contraction due to cooling. All epochs changed between 7 to 1 17 days (990928 to000 1 16), showed 200 to 400 micro strain lengthening and shortening. The contraction and extension existed in each epoch, but the final strain was extension in E-W in Epoch land 6, contraction in E-W direction during epochs 2-3-4-5 and 7. The second pair of stakes hammered about 20 cm deep into the deep soils(more than 1 m) , near summit, where the colors change between 19 to 29mm in InSAR image(9809 13 to 990620). Additional information is included in the original abstract.

  15. The effect of epoch length on estimated EEG functional connectivity and brain network organisation

    NASA Astrophysics Data System (ADS)

    Fraschini, Matteo; Demuru, Matteo; Crobe, Alessandra; Marrosu, Francesco; Stam, Cornelis J.; Hillebrand, Arjan

    2016-06-01

    Objective. Graph theory and network science tools have revealed fundamental mechanisms of functional brain organization in resting-state M/EEG analysis. Nevertheless, it is still not clearly understood how several methodological aspects may bias the topology of the reconstructed functional networks. In this context, the literature shows inconsistency in the chosen length of the selected epochs, impeding a meaningful comparison between results from different studies. Approach. The aim of this study was to provide a network approach insensitive to the effects that epoch length has on functional connectivity and network reconstruction. Two different measures, the phase lag index (PLI) and the amplitude envelope correlation (AEC) were applied to EEG resting-state recordings for a group of 18 healthy volunteers using non-overlapping epochs with variable length (1, 2, 4, 6, 8, 10, 12, 14 and 16 s). Weighted clustering coefficient (CCw), weighted characteristic path length (L w) and minimum spanning tree (MST) parameters were computed to evaluate the network topology. The analysis was performed on both scalp and source-space data. Main results. Results from scalp analysis show a decrease in both mean PLI and AEC values with an increase in epoch length, with a tendency to stabilize at a length of 12 s for PLI and 6 s for AEC. Moreover, CCw and L w show very similar behaviour, with metrics based on AEC more reliable in terms of stability. In general, MST parameters stabilize at short epoch lengths, particularly for MSTs based on PLI (1-6 s versus 4-8 s for AEC). At the source-level the results were even more reliable, with stability already at 1 s duration for PLI-based MSTs. Significance. The present work suggests that both PLI and AEC depend on epoch length and that this has an impact on the reconstructed network topology, particularly at the scalp-level. Source-level MST topology is less sensitive to differences in epoch length, therefore enabling the comparison of brain network topology between different studies.

  16. Multithreading with separate data to improve the performance of Backpropagation method

    NASA Astrophysics Data System (ADS)

    Dhamma, Mulia; Zarlis, Muhammad; Budhiarti Nababan, Erna

    2017-12-01

    Backpropagation is one method of artificial neural network that can make a prediction for a new data with learning by supervised of the past data. The learning process of backpropagation method will become slow if we give too much data for backpropagation method to learn the data. Multithreading with a separate data inside of each thread are being used in order to improve the performance of backpropagtion method . Base on the research for 39 data and also 5 times experiment with separate data into 2 thread, the result showed that the average epoch become 6490 when using 2 thread and 453049 epoch when using only 1 thread. The most lowest epoch for 2 thread is 1295 and 1 thread is 356116. The process of improvement is caused by the minimum error from 2 thread that has been compared to take the weight and bias value. This process will be repeat as long as the backpropagation do learning.

  17. The extended atmosphere of Lambda Pavonis at the time of the emergence of H-emissions from minimum intensity

    NASA Technical Reports Server (NTRS)

    Sahade, Jorge; Rovira, Marta; Ringuelet, Adela E.; Kondo, Yoji; Cidale, Lydia

    1988-01-01

    A study of the Be star Lambda Pavonis, particularly of the changes in the Balmer discontinuity in the interval 1949-1982, is presented. Nearly simultaneous observations carried out with the ESO 1.5 m reflector at La Silla and with the IUE satellite correspond to an epoch when the H emission is starting to increase intensity immediately after having reached its minimum strength. These observations suggest the presence of four distinct regions of line formation, with the material moving outward in the transition region.

  18. Characterization of REM sleep without atonia in patients with narcolepsy and idiopathic hypersomnia using AASM scoring manual criteria.

    PubMed

    DelRosso, Lourdes M; Chesson, Andrew L; Hoque, Romy

    2013-07-15

    The AASM Manual for the Scoring of Sleep and Associated Events (Manual) has provided standardized definitions for tonic and phasic REM sleep without atonia (RSWA). This study used Manual criteria to characterize REM sleep in patients with narcolepsy and idiopathic hypersomnia (IH). A retrospective review of PSG data from ICSD-2 defined patients with narcolepsy or IH, performed by two board certified sleep medicine physicians. Data compiled included REM sleep epochs and the presence in REM sleep of epochs scored as sustained muscle activity (tonic), and excessive transient muscle activity (phasic) as defined by Manual criteria. PSG data from 8 narcolepsy patients (mean age: 27.5 years; age range: 11-55) showed mean ± standard deviation values for: total REM sleep epochs 205 ± 46.1; RSWA/ phasic epochs 56.1 ± 25.4; and RSWA/tonic epochs 15.0 ± 10.7. PSG data from 8 IH patients (mean age: 33.1 years; age range: 20-57) showed mean ± standard deviation values of total REM sleep epochs 163.8 ± 67.9; RSWA/phasic epochs 6.2 ± 3.5; and RSWA/tonic epochs 0.2 ± 0.4. Comparison revealed intergroup differences in phasic REM sleep (p < 0.01) and tonic REM sleep (p < 0.01) were significantly increased in narcoleptics compared to IH. Our retrospective analysis showed that RSWA phasic activity and RSWA tonic activity are significantly increased in patients meeting ICSD-2 criteria for narcolepsy compared to patients meeting ICSD-2 criteria for IH. This robust difference, with further validation, could be useful as electrophysiological criteria differentiating the two disorders and understanding the physiological differences.

  19. Peculiarities of cosmic ray modulation in the solar minimum 23/24

    NASA Astrophysics Data System (ADS)

    Alania, M. V.; Modzelewska, R.; Wawrzynczak, A.

    2014-06-01

    We study changes of the galactic cosmic ray (GCR) intensity for the ending period of the solar cycle 23 and the beginning of the solar cycle 24 using neutron monitors experimental data. We show that an increase of the GCR intensity in 2009 is generally related with decrease of the solar wind velocity U, the strength B of the interplanetary magnetic field (IMF), and the drift in negative (A < 0) polarity epoch. We present that temporal changes of rigidity dependence of the GCR intensity variation, before reaching maximum level in 2009 and after it, do not noticeably differ from each other. The rigidity spectrum of the GCR intensity variations calculated based on neutron monitors data (for rigidities > 10 GV) is hard in the minimum and near-minimum epoch. We do not recognize any nonordinary changes in the physical mechanism of modulation of the GCR intensity in the rigidity range of GCR particles to which neutron monitors respond. We compose 2-D nonstationary model of transport equation to describe variations of the GCR intensity for 1996-2012 including the A > 0 (1996-2001) and the A < 0 (2002-2012) periods; diffusion coefficient of cosmic rays for rigidity 10-15 GV is increased by 30% in 2009 (A < 0) comparing with 1996 (A > 0). We believe that the proposed model is relatively realistic, and obtained results are satisfactorily compatible with neutron monitors data.

  20. Description of nighttime cough epochs in patients with stable COPD GOLD II-IV.

    PubMed

    Fischer, Patrick; Gross, Volker; Kroenig, Johannes; Weissflog, Andreas; Hildebrandt, Olaf; Sohrabi, Keywan; Koehler, Ulrich

    Chronic cough is one of the main symptoms of COPD. Ambulatory objective monitoring provides novel insights into the determinants and characteristics of nighttime cough in COPD. Nighttime cough was monitored objectively by LEOSound lung sound monitor in patients with stable COPD II-IV. In 30 patients, with 10 patients in each stage group, nighttime cough was analyzed for epoch frequency, epoch severity (epoch length and coughs per epoch), and pattern (productive or nonproductive). Cough was found in all patients ranging from 1 to 294 events over the recording period. In 29 patients, cough epochs were monitored, ranging from 1 to 75 epochs. The highest amount of cough epochs was found in patients with COPD stage III. Active smokers had significantly more productive cough epochs (61%) than nonsmokers (24%). We found a high rate of nighttime cough epochs in patients with COPD, especially in those in stage III. Productive cough was predominantly found in patients with persistent smoking. LEOSound lung sound monitor offers a practical and valuable opportunity to evaluate cough objectively.

  1. The Influence of Epoch Length on Physical Activity Patterns Varies by Child's Activity Level

    ERIC Educational Resources Information Center

    Nettlefold, Lindsay; Naylor, P. J.; Warburton, Darren E. R.; Bredin, Shannon S. D.; Race, Douglas; McKay, Heather A.

    2016-01-01

    Purpose: Patterns of physical activity (PA) and sedentary time, including volume of bouted activity, are important health indicators. However, the effect of accelerometer epoch length on measurement of these patterns and associations with health outcomes in children remain unknown. Method: We measured activity patterns in 308 children (52% girls,…

  2. Low-noise encoding of active touch by layer 4 in the somatosensory cortex.

    PubMed

    Hires, Samuel Andrew; Gutnisky, Diego A; Yu, Jianing; O'Connor, Daniel H; Svoboda, Karel

    2015-08-06

    Cortical spike trains often appear noisy, with the timing and number of spikes varying across repetitions of stimuli. Spiking variability can arise from internal (behavioral state, unreliable neurons, or chaotic dynamics in neural circuits) and external (uncontrolled behavior or sensory stimuli) sources. The amount of irreducible internal noise in spike trains, an important constraint on models of cortical networks, has been difficult to estimate, since behavior and brain state must be precisely controlled or tracked. We recorded from excitatory barrel cortex neurons in layer 4 during active behavior, where mice control tactile input through learned whisker movements. Touch was the dominant sensorimotor feature, with >70% spikes occurring in millisecond timescale epochs after touch onset. The variance of touch responses was smaller than expected from Poisson processes, often reaching the theoretical minimum. Layer 4 spike trains thus reflect the millisecond-timescale structure of tactile input with little noise.

  3. Pulse Wave Amplitude Drops during Sleep are Reliable Surrogate Markers of Changes in Cortical Activity

    PubMed Central

    Delessert, Alexandre; Espa, Fabrice; Rossetti, Andrea; Lavigne, Gilles; Tafti, Mehdi; Heinzer, Raphael

    2010-01-01

    Background: During sleep, sudden drops in pulse wave amplitude (PWA) measured by pulse oximetry are commonly associated with simultaneous arousals and are thought to result from autonomic vasoconstriction. In the present study, we determine whether PWA drops were associated with changes in cortical activity as determined by EEG spectral analysis. Methods: A 20% decrease in PWA was chosen as a minimum for a drop. A total of 1085 PWA drops from 10 consecutive sleep recordings were analyzed. EEG spectral analysis was performed over 5 consecutive epochs of 5 seconds: 2 before, 1 during, and 2 after the PWA drop. EEG spectral analysis was performed over delta, theta, alpha, sigma, and beta frequency bands. Within each frequency band, power density was compared across the five 5-sec epochs. Presence or absence of visually scored EEG arousals were adjudicated by an investigator blinded to the PWA signal and considered associated with PWA drop if concomitant. Results: A significant increase in EEG power density in all EEG frequency bands was found during PWA drops (P < 0.001) compared to before and after drop. Even in the absence of visually scored arousals, PWA drops were associated with a significant increase in EEG power density (P < 0.001) in most frequency bands. Conclusions: Drops in PWA are associated with a significant increase in EEG power density, suggesting that these events can be used as a surrogate for changes in cortical activity during sleep. This approach may prove of value in scoring respiratory events on limited-channel (type III) portable monitors. Citation: Delessert A; Espa F; Rossetti A; Lavigne G; Tafti M; Heinzer R. Pulse wave amplitude drops during sleep are reliable surrogate markers of changes in cortical activity. SLEEP 2010;33(12):1687-1692. PMID:21120131

  4. Efficacy of brain-computer interface-driven neuromuscular electrical stimulation for chronic paresis after stroke.

    PubMed

    Mukaino, Masahiko; Ono, Takashi; Shindo, Keiichiro; Fujiwara, Toshiyuki; Ota, Tetsuo; Kimura, Akio; Liu, Meigen; Ushiba, Junichi

    2014-04-01

    Brain computer interface technology is of great interest to researchers as a potential therapeutic measure for people with severe neurological disorders. The aim of this study was to examine the efficacy of brain computer interface, by comparing conventional neuromuscular electrical stimulation and brain computer interface-driven neuromuscular electrical stimulation, using an A-B-A-B withdrawal single-subject design. A 38-year-old male with severe hemiplegia due to a putaminal haemorrhage participated in this study. The design involved 2 epochs. In epoch A, the patient attempted to open his fingers during the application of neuromuscular electrical stimulation, irrespective of his actual brain activity. In epoch B, neuromuscular electrical stimulation was applied only when a significant motor-related cortical potential was observed in the electroencephalogram. The subject initially showed diffuse functional magnetic resonance imaging activation and small electro-encephalogram responses while attempting finger movement. Epoch A was associated with few neurological or clinical signs of improvement. Epoch B, with a brain computer interface, was associated with marked lateralization of electroencephalogram (EEG) and blood oxygenation level dependent responses. Voluntary electromyogram (EMG) activity, with significant EEG-EMG coherence, was also prompted. Clinical improvement in upper-extremity function and muscle tone was observed. These results indicate that self-directed training with a brain computer interface may induce activity- dependent cortical plasticity and promote functional recovery. This preliminary clinical investigation encourages further research using a controlled design.

  5. Combinations of Epoch Durations and Cut-Points to Estimate Sedentary Time and Physical Activity among Adolescents

    ERIC Educational Resources Information Center

    Fröberg, Andreas; Berg, Christina; Larsson, Christel; Boldemann, Cecilia; Raustorp, Anders

    2017-01-01

    The purpose of the current study was to investigate how combinations of different epoch durations and cut-points affect the estimations of sedentary time and physical activity in adolescents. Accelerometer data from 101 adolescents were derived and 30 combinations were used to estimate sedentary time, light, moderate, vigorous, and combined…

  6. Changes in solar quiet magnetic variations since the Maunder Minimum: A comparison of historical observations and model simulations

    NASA Astrophysics Data System (ADS)

    Cnossen, Ingrid; Matzka, Jürgen

    2016-10-01

    Magnetic measurements going back to the eighteenth century offer a unique opportunity to study multicentennial changes in the upper atmosphere. We analyzed measurements from Rome and Mannheim from May 1782 to May 1783 and measurements from Greenwich, St. Helena, Cape of Good Hope, and Singapore from May 1841 to May 1842. A comparison of the daily magnetic variations in these historical data with modern-day observations from 2010 at nearby stations (where available) showed notable differences in the amplitude and/or phase of the X and Y components. Model simulations indicated that these can be explained at least to some extent by changes in the Earth's main magnetic field. Changes in the main field strength and the northwestward movement of the magnetic equator, in particular in the region of the South Atlantic Anomaly, have caused changes in the positioning, shape, and strength of the equivalent current vortices in the ionosphere that result in the magnetic perturbations on the ground. Differences in solar activity between the historical and modern epochs, which were all near solar minima, were too small to have a notable effect on the ground magnetic perturbations. However, in regions where main magnetic field changes have been relatively small for the last 400 years, e.g., in Singapore, the effects of a long-term increase in solar activity from Maunder Minimum conditions to normal solar minimum conditions (an increase in F10.7 of 35 solar flux units) were comparable to the effects of geomagnetic main field changes.

  7. Potential impacts of a future Grand Solar Minimum on decadal regional climate change and interannual hemispherical climate variability

    NASA Astrophysics Data System (ADS)

    Spiegl, Tobias; Langematz, Ulrike

    2016-04-01

    The political, technical and socio-economic developments of the next decades will determine the magnitude of 21st century climate change, since they are inextricably linked to future anthropogenic greenhouse gas emissions. To assess the range of uncertainty that is related to these developments, it is common to assume different emission scenarios for 21st climate projections. While the uncertainties associated with the anthropogenic greenhouse gas forcing have been studied intensely, the contribution of natural climate drivers (particularly solar variability) to recent and future climate change are subject of intense debate. The past 1,000 years featured at least 5 excursions (lasting 60-100 years) of exceptionally low solar activity, induced by a weak magnetic field of the Sun, so called Grand Solar Minima. While the global temperature response to such a decrease in solar activity is assumed to be rather small, nonlinear mechanisms in the climate system might amplify the regional temperature signal. This hypothesis is supported by the last Grand Solar Minimum (the Maunder Minimum, 1645-1715) which coincides with the Little Ice Age, an epoch which is characterized by severe cold and hardship over Europe, North America and Asia. The long-lasting minimum of Solar Cycle 23 as well as the overall weak maximum of Cycle 24 reveal the possibility for a return to Grand Solar Minimum conditions within the next decades. The quantification of the implications of such a projected decrease in solar forcing is of ultimate importance, given the on-going public discussion of the role of carbon dioxide emissions for global warming, and the possible role a cooling due to decreasing solar activity could be ascribed to. Since there is still no clear consensus about the actual strength of the Maunder Minimum, we used 3 acknowledged solar reconstruction datasets that show significant differences in both, total solar irradiance (TSI) and spectral irradiance (SSI) to simulate a future Grand Solar Minimum under RCP6.0 conditions. The results obtained were compared to a RCP6.0 simulation that was carried out using the CCMI recommendations for a 21st century solar forcing. We used the ECHAM/MESSy Atmospheric Chemistry (EMAC) chemistry-climate model that incorporates interactive ozone chemistry, a high-resolution shortwave radiation scheme, a high model top (0.01 hPa) and is coupled to a 3D ocean general circulation model. We focused on the regional responses to a future Grand Solar Minimum and interannual variability patterns (i.e. the Northern and Southern Annular Mode (NAM/SAM)).

  8. What time does the recovery phase of geomagnetic storms start: A superposed epoch analysis

    NASA Astrophysics Data System (ADS)

    Du, A.; Zhang, Y.; Ou, J.; Luo, H.

    2015-12-01

    It is well known that the recovery phase of the geomagnetic storms start during Dst reaches a minimum. This present paper is a discussion of recovery phase onset of a superposed epoch analysis of 247 storm events (-450 < Dst < -50 nT). The data of the solar wind parameters, the geomagnetic index AE and Dst are by means of 1 hour OMNI database. The energy budget for the driver and decay terms introduced by Burton et al. (1975) are checked. As might be expected, the recovery phase of geomagnetic storms starts when the decay term is greater than the driver term. The balance of the decay and driver terms is also dependent on the solar wind energy input during the initial phase. In general, at the onset of the recovery phase, EK-L decreases to 70% of a maximum of EK-L.

  9. MODULATION OF GALACTIC ELECTRONS IN THE HELIOSPHERE DURING THE UNUSUAL SOLAR MINIMUM OF 2006–2009: A MODELING APPROACH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Potgieter, M. S.; Vos, E. E.; Munini, R.

    The last solar minimum activity period, and the consequent minimum modulation conditions for cosmic rays, was unusual. The highest levels of Galactic protons were recorded at Earth in late 2009 in contrast to expectations. A comprehensive model was used to study the proton modulation for the period from 2006 to 2009 in order to determine what basic processes were responsible for solar modulation during this period and why it differs from proton modulation during previous solar minimum modulation periods. This established model is now applied to studying the solar modulation of electron spectra as observed for 80 MeV–30 GeV bymore » the PAMELA space detector from mid-2006 to the end of 2009. Over this period the heliospheric magnetic field had decreased significantly until the end of 2009 while the waviness of the heliospheric current sheet decreased moderately and the observed electron spectra increased by a factor of ∼1.5 at 1.0 GeV to ∼3.5 at 100 MeV. In order to reproduce the modulation evident from seven consecutive semesters, the diffusion coefficients had to increase moderately while maintaining the basic rigidity dependence. It is confirmed that the main diffusion coefficients are independent of rigidity below ∼0.5 GV, while the drift coefficient had to be reduced below this value. The 2006–2009 solar minimum epoch indeed was different than previously observed minima, at least since the beginning of the space exploration era. This period could be called “diffusion-dominated” as was also found for the modulation of protons.« less

  10. Evaluation of mirrored muscle activity in patients with Complex Regional Pain Syndrome.

    PubMed

    Bank, Paulina J M; Peper, C Lieke E; Marinus, Johan; Beek, Peter J; van Hilten, Jacobus J

    2014-10-01

    Motor dysfunction in Complex Regional Pain Syndrome (CRPS) has been associated with bilateral changes in central motor processing, suggesting abnormal coupling between the affected and unaffected limb. We evaluated the occurrence of involuntary muscle activity in a limb during voluntary movements of the contralateral limb (i.e., mirror activity) in unilaterally affected patients to examine disinhibition of contralateral motor activity in CRPS. Mirror activity was examined during unimanual rhythmic flexion-extension movements of the wrist through in-depth analysis of electromyography recordings from the passive arm in 20 CRPS patients and 40 controls. The number of mirror-epochs was comparable for both arms in both CRPS patients and controls. Mirror-epochs in the affected arm of patients were comparable to those in controls. Mirror-epochs in the unaffected arm were shorter and showed less resemblance (in terms of rhythm and timing) to activity of the homologous muscle in the moving arm compared to mirror-epochs in controls. No evidence for disinhibition of contralateral motor activity was found during unimanual movement. Although motor dysfunction in CRPS has been associated with bilateral changes in cortical motor processing, the present findings argue against disinhibition of interhemispheric projections to homologous muscles in the contralateral limb during unimanual movement. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  11. Analysis of short single rest/activation epoch fMRI by self-organizing map neural network

    NASA Astrophysics Data System (ADS)

    Erberich, Stephan G.; Dietrich, Thomas; Kemeny, Stefan; Krings, Timo; Willmes, Klaus; Thron, Armin; Oberschelp, Walter

    2000-04-01

    Functional magnet resonance imaging (fMRI) has become a standard non invasive brain imaging technique delivering high spatial resolution. Brain activation is determined by magnetic susceptibility of the blood oxygen level (BOLD effect) during an activation task, e.g. motor, auditory and visual tasks. Usually box-car paradigms have 2 - 4 rest/activation epochs with at least an overall of 50 volumes per scan in the time domain. Statistical test based analysis methods need a large amount of repetitively acquired brain volumes to gain statistical power, like Student's t-test. The introduced technique based on a self-organizing neural network (SOM) makes use of the intrinsic features of the condition change between rest and activation epoch and demonstrated to differentiate between the conditions with less time points having only one rest and one activation epoch. The method reduces scan and analysis time and the probability of possible motion artifacts from the relaxation of the patients head. Functional magnet resonance imaging (fMRI) of patients for pre-surgical evaluation and volunteers were acquired with motor (hand clenching and finger tapping), sensory (ice application), auditory (phonological and semantic word recognition task) and visual paradigms (mental rotation). For imaging we used different BOLD contrast sensitive Gradient Echo Planar Imaging (GE-EPI) single-shot pulse sequences (TR 2000 and 4000, 64 X 64 and 128 X 128, 15 - 40 slices) on a Philips Gyroscan NT 1.5 Tesla MR imager. All paradigms were RARARA (R equals rest, A equals activation) with an epoch width of 11 time points each. We used the self-organizing neural network implementation described by T. Kohonen with a 4 X 2 2D neuron map. The presented time course vectors were clustered by similar features in the 2D neuron map. Three neural networks were trained and used for labeling with the time course vectors of one, two and all three on/off epochs. The results were also compared by using a Kolmogorov-Smirnov statistical test of all 66 time points. To remove non- periodical time courses from training an auto-correlation function and bandwidth limiting Fourier filtering in combination with Gauss temporal smoothing was used. None of the trained maps, with one, two and three epochs, were significantly different which indicates that the feature space of only one on/off epoch is sufficient to differentiate between the rest and task condition. We found, that without pre-processing of the data no meaningful results can be achieved because of the huge amount of the non-activated and background voxels represents the majority of the features and is therefore learned by the SOM. Thus it is crucial to remove unnecessary capacity load of the neural network by selection of the training input, using auto-correlation function and/or Fourier spectrum analysis. However by reducing the time points to one rest and one activation epoch either strong auto- correlation or a precise periodical frequency is vanishing. Self-organizing maps can be used to separate rest and activation epochs of with only a 1/3 of the usually acquired time points. Because of the nature of the SOM technique, the pattern or feature separation, only the presence of a state change between the conditions is necessary for differentiation. Also the variance of the individual hemodynamic response function (HRF) and the variance of the spatial different regional cerebral blood flow (rCBF) is learned from the subject and not compared with a fixed model done by statistical evaluation. We found that reducing the information to only a few time points around the BOLD effect was not successful due to delays of rCBF and the insufficient extension of the BOLD feature in the time space. Especially for patient routine observation and pre-surgical planing a reduced scan time is of interest.

  12. Detection and description of non-linear interdependence in normal multichannel human EEG data.

    PubMed

    Breakspear, M; Terry, J R

    2002-05-01

    This study examines human scalp electroencephalographic (EEG) data for evidence of non-linear interdependence between posterior channels. The spectral and phase properties of those epochs of EEG exhibiting non-linear interdependence are studied. Scalp EEG data was collected from 40 healthy subjects. A technique for the detection of non-linear interdependence was applied to 2.048 s segments of posterior bipolar electrode data. Amplitude-adjusted phase-randomized surrogate data was used to statistically determine which EEG epochs exhibited non-linear interdependence. Statistically significant evidence of non-linear interactions were evident in 2.9% (eyes open) to 4.8% (eyes closed) of the epochs. In the eyes-open recordings, these epochs exhibited a peak in the spectral and cross-spectral density functions at about 10 Hz. Two types of EEG epochs are evident in the eyes-closed recordings; one type exhibits a peak in the spectral density and cross-spectrum at 8 Hz. The other type has increased spectral and cross-spectral power across faster frequencies. Epochs identified as exhibiting non-linear interdependence display a tendency towards phase interdependencies across and between a broad range of frequencies. Non-linear interdependence is detectable in a small number of multichannel EEG epochs, and makes a contribution to the alpha rhythm. Non-linear interdependence produces spatially distributed activity that exhibits phase synchronization between oscillations present at different frequencies. The possible physiological significance of these findings are discussed with reference to the dynamical properties of neural systems and the role of synchronous activity in the neocortex.

  13. Solar wind and coronal structure near sunspot minimum - Pioneer and SMM observations from 1985-1987

    NASA Technical Reports Server (NTRS)

    Mihalov, J. D.; Barnes, A.; Hundhausen, A. J.; Smith, E. J.

    1990-01-01

    Changes in solar wind speed and magnetic polarity observed at the Pioneer spacecraft are discussed here in terms of the changing magnetic geometry implied by SMM coronagraph observations over the period 1985-1987. The pattern of recurrent solar wind streams, the long-term average speed, and the sector polarity of the interplanetary magnetic field all changed in a manner suggesting both a temporal variation, and a changing dependence on heliographic latitude. Coronal observations during this epoch show a systematic variation in coronal structure and the magnetic structure imposed on the expanding solar wind. These observations suggest interpretation of the solar wind speed variations in terms of the familiar model where the speed increases with distance from a nearly flat interplanetary current sheet, and where this current sheet becomes aligned with the solar equatorial plane as sunspot minimum approaches, but deviates rapidly from that orientation after minimum.

  14. Black hole masses in active galactic nuclei

    NASA Astrophysics Data System (ADS)

    Denney, Kelly D.

    2010-11-01

    We present the complete results from two, high sampling-rate, multi-month, spectrophotometric reverberation mapping campaigns undertaken to obtain either new or improved Hbeta reverberation lag measurements for several relatively low-luminosity active galactic nuclei (AGNs). We have reliably measured the time delay between variations in the continuum and Hbeta emission line in seven local Seyfert 1 galaxies. These measurements are used to calculate the mass of the supermassive black hole at the center of each of these AGNs. We place our results in context to the most current calibration of the broad-line region (BLR) RBLR-L relationship, where our results remove many outliers and significantly reduce the scatter at the low-luminosity end of this relationship. A detailed analysis of the data from our high sampling rate, multi-month reverberation mapping campaign in 2007 reveals that the Hbeta emission region within the BLRs of several nearby AGNs exhibit a variety of kinematic behaviors. Through a velocity-resolved reverberation analysis of the broad Hbeta emission-line flux variations in our sample, we reconstruct velocity-resolved kinematic signals for our entire sample and clearly see evidence for outflowing, infalling, and virialized BLR gas motions in NGC 3227, NGC 3516, and NGC 5548, respectively. Finally, we explore the nature of systematic errors that can arise in measurements of black hole masses from single-epoch spectra of AGNs by utilizing the many epochs available for NGC 5548 and PG1229+204 from reverberation mapping databases. In particular, we examine systematics due to AGN variability, contamination due to constant spectral components (i.e., narrow lines and host galaxy flux), data quality (i.e., signal-to-noise ratio, S/N), and blending of spectral features. We investigate the effect that each of these systematics has on the precision and accuracy of single-epoch masses calculated from two commonly-used line-width measures by comparing these results to recent reverberation mapping studies. We then present an error budget which summarizes the minimum observable uncertainties as well as the amount of additional scatter and/or systematic offset that can be expected from the individual sources of error investigated.

  15. The validity of activity monitors for measuring sleep in elite athletes.

    PubMed

    Sargent, Charli; Lastella, Michele; Halson, Shona L; Roach, Gregory D

    2016-10-01

    There is a growing interest in monitoring the sleep of elite athletes. Polysomnography is considered the gold standard for measuring sleep, however this technique is impractical if the aim is to collect data simultaneously with multiple athletes over consecutive nights. Activity monitors may be a suitable alternative for monitoring sleep, but these devices have not been validated against polysomnography in a population of elite athletes. Participants (n=16) were endurance-trained cyclists participating in a 6-week training camp. A total of 122 nights of sleep were recorded with polysomnography and activity monitors simultaneously. Agreement, sensitivity, and specificity were calculated from epoch-for-epoch comparisons of polysomnography and activity monitor data. Sleep variables derived from polysomnography and activity monitors were compared using paired t-tests. Activity monitor data were analysed using low, medium, and high sleep-wake thresholds. Epoch-for-epoch comparisons showed good agreement between activity monitors and polysomnography for each sleep-wake threshold (81-90%). Activity monitors were sensitive to sleep (81-92%), but specificity differed depending on the threshold applied (67-82%). Activity monitors underestimated sleep duration (18-90min) and overestimated wake duration (4-77min) depending on the threshold applied. Applying the correct sleep-wake threshold is important when using activity monitors to measure the sleep of elite athletes. For example, the default sleep-wake threshold (>40 activity counts=wake) underestimates sleep duration by ∼50min and overestimates wake duration by ∼40min. In contrast, sleep-wake thresholds that have a high sensitivity to sleep (>80 activity counts=wake) yield the best combination of agreement, sensitivity, and specificity. Copyright © 2015 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  16. [Walking abnormalities in children].

    PubMed

    Segawa, Masaya

    2010-11-01

    Walking is a spontaneous movement termed locomotion that is promoted by activation of antigravity muscles by serotonergic (5HT) neurons. Development of antigravity activity follows 3 developmental epochs of the sleep-wake (S-W) cycle and is modulated by particular 5HT neurons in each epoch. Activation of antigravity activities occurs in the first epoch (around the age of 3 to 4 months) as restriction of atonia in rapid eye movement (REM) stage and development of circadian S-W cycle. These activities strengthen in the second epoch, with modulation of day-time sleep and induction of crawling around the age of 8 months and induction of walking by 1 year. Around the age of 1 year 6 months, absence of guarded walking and interlimb cordination is observed along with modulation of day-time sleep to once in the afternoon. Bipedal walking in upright position occurs in the third epoch, with development of a biphasic S-W cycle by the age of 4-5 years. Patients with infantile autism (IA), Rett syndrome (RTT), or Tourette syndrome (TS) show failure in the development of the first, second, or third epoch, respectively. Patients with IA fail to develop interlimb coordination; those with RTT, crawling and walking; and those with TS, walking in upright posture. Basic pathophysiology underlying these condition is failure in restricting atonia in REM stage; this induces dysfunction of the pedunculopontine nucleus and consequently dys- or hypofunction of the dopamine (DA) neurons. DA hypofunction in the developing brain, associated with compensatory upward regulation of the DA receptors causes psychobehavioral disorders in infancy (IA), failure in synaptogenesis in the frontal cortex and functional development of the motor and associate cortexes in late infancy through the basal ganglia (RTT), and failure in functional development of the prefrontal cortex through the basal ganglia (TS). Further, locomotion failure in early childhood causes failure in development of functional specialization of the cortex through the spinal stepping generator-fastigial nucleus-thalamus-cortex pathway. Early detection of locomotion failure and early adjustment of this condition through environmental factors can prevent the development of higher cortical dysfunction.

  17. Assessment of Differing Definitions of Accelerometer Nonwear Time

    ERIC Educational Resources Information Center

    Evenson, Kelly R.; Terry, James W., Jr.

    2009-01-01

    Measuring physical activity with objective tools, such as accelerometers, is becoming more common. Accelerometers measure acceleration multiple times within a given frequency and summarize this as a count over a pre-specified time period or epoch. The resultant count represents acceleration over the epoch length. Accelerometers eliminate biases…

  18. Planetary resonances, bi-stable oscillation modes, and solar activity cycles

    NASA Technical Reports Server (NTRS)

    Sleeper, H. P., Jr.

    1972-01-01

    The natural resonance structure of the planets in the solar system yields resonance periods of 11.08 and 180 years. The 11.08 year period is due to resonance of the sidereal periods of the three inner planets. The 180-year period is due to synodic resonances of the four major planets. These periods are also observed in the sunspot time series. The 11-year sunspot cycles from 1 to 19 are separated into categories of positive and negative cycles, Mode 1 and Mode 2 cycles, and typical and anomalous cycles. Each category has a characteristic shape, magnitude, or duration, so that statistical prediction techniques are improved when a cycle can be classified in a given category. These categories provide evidence for bistable modes of solar oscillation. The next minimum is expected in 1977 and the next maximum in 1981 or later. These epoch values are 2.5 years later than those based on typical cycle characteristics.

  19. Supernova bangs as a tool to study big bang

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blinnikov, S. I., E-mail: Sergei.Blinnikov@itep.ru

    Supernovae and gamma-ray bursts are the most powerful explosions in observed Universe. This educational review tells about supernovae and their applications in cosmology. It is explained how to understand the production of light in the most luminous events with minimum required energy of explosion. These most luminous phenomena can serve as primary cosmological distance indicators. Comparing the observed distance dependence on red shift with theoretical models one can extract information on evolution of the Universe from Big Bang until our epoch.

  20. Specificity of Direct Transition from Wake to REM Sleep in Orexin/ataxin-3 Transgenic Narcoleptic Mice

    PubMed Central

    Fujiki, Nobuhiro; Cheng, Timothy; Yoshino, Fuyumi; Nishino, Seiji

    2009-01-01

    To create operational criteria for polygraphic assessments of direct transitions from wake to REM sleep (DREM), as a murine analog of human cataplexy, we have analyzed DREM episodes in congenic lines of orexin/ataxin-3 transgenic [TG] mice and wild-type littermates. The sleep stage of each 10-second epoch was visually scored using our standard criteria. Specificity of DREM for narcoleptic TG mice and sensitivity to detect DREM was evaluated using different DREM criteria. We found that DREM transitions by 10-second epoch scoring are not specific for narcoleptic TG mice and also occur in WT mice during light period. These wake-to-REM transitions in WT mice (also seen in TG mice during light period) were characteristically different from DREM transitions in TG mice during dark period; they tended to occur as brief bouts of wakefulness interrupting extended episodes of REM sleep, suggesting that these transitions do not represent abnormal manifestations of REM sleep. We therefore defined the DREM transitions by requiring a minimum number of preceding wake epochs. Requiring no fewer than four consecutive epochs of wakefulness produced the best combination of specificity (95.9%) and sensitivity (66.0%). By definition, DREM in dark-period is 100% specific to narcolepsy and was 95.9% specific overall. In addition, we found that desipramine, a trycyclic anticataplectic, potently reduces DREM, while two wake-promoting compounds have moderate (d-amphetamine) and no (modafinil) effect on DREM; the effects mirror the anticataplectic effects of these compounds reported in canine and human narcolepsy. Our definition of DREM in murine narcolepsy may provide good electrophysiological measure for cataplexy-equivalent episodes. PMID:19416673

  1. Electrical source imaging of interictal spikes using multiple sparse volumetric priors for presurgical epileptogenic focus localization

    PubMed Central

    Strobbe, Gregor; Carrette, Evelien; López, José David; Montes Restrepo, Victoria; Van Roost, Dirk; Meurs, Alfred; Vonck, Kristl; Boon, Paul; Vandenberghe, Stefaan; van Mierlo, Pieter

    2016-01-01

    Electrical source imaging of interictal spikes observed in EEG recordings of patients with refractory epilepsy provides useful information to localize the epileptogenic focus during the presurgical evaluation. However, the selection of the time points or time epochs of the spikes in order to estimate the origin of the activity remains a challenge. In this study, we consider a Bayesian EEG source imaging technique for distributed sources, i.e. the multiple volumetric sparse priors (MSVP) approach. The approach allows to estimate the time courses of the intensity of the sources corresponding with a specific time epoch of the spike. Based on presurgical averaged interictal spikes in six patients who were successfully treated with surgery, we estimated the time courses of the source intensities for three different time epochs: (i) an epoch starting 50 ms before the spike peak and ending at 50% of the spike peak during the rising phase of the spike, (ii) an epoch starting 50 ms before the spike peak and ending at the spike peak and (iii) an epoch containing the full spike time period starting 50 ms before the spike peak and ending 230 ms after the spike peak. To identify the primary source of the spike activity, the source with the maximum energy from 50 ms before the spike peak till 50% of the spike peak was subsequently selected for each of the time windows. For comparison, the activity at the spike peaks and at 50% of the peaks was localized using the LORETA inversion technique and an ECD approach. Both patient-specific spherical forward models and patient-specific 5-layered finite difference models were considered to evaluate the influence of the forward model. Based on the resected zones in each of the patients, extracted from post-operative MR images, we compared the distances to the resection border of the estimated activity. Using the spherical models, the distances to the resection border for the MSVP approach and each of the different time epochs were in the same range as the LORETA and ECD techniques. We found distances smaller than 23 mm, with robust results for all the patients. For the finite difference models, we found that the distances to the resection border for the MSVP inversions of the full spike time epochs were generally smaller compared to the MSVP inversions of the time epochs before the spike peak. The results also suggest that the inversions using the finite difference models resulted in slightly smaller distances to the resection border compared to the spherical models. The results we obtained are promising because the MSVP approach allows to study the network of the estimated source-intensities and allows to characterize the spatial extent of the underlying sources. PMID:26958464

  2. An automated sleep-state classification algorithm for quantifying sleep timing and sleep-dependent dynamics of electroencephalographic and cerebral metabolic parameters

    PubMed Central

    Rempe, Michael J; Clegern, William C; Wisor, Jonathan P

    2015-01-01

    Introduction Rodent sleep research uses electroencephalography (EEG) and electromyography (EMG) to determine the sleep state of an animal at any given time. EEG and EMG signals, typically sampled at >100 Hz, are segmented arbitrarily into epochs of equal duration (usually 2–10 seconds), and each epoch is scored as wake, slow-wave sleep (SWS), or rapid-eye-movement sleep (REMS), on the basis of visual inspection. Automated state scoring can minimize the burden associated with state and thereby facilitate the use of shorter epoch durations. Methods We developed a semiautomated state-scoring procedure that uses a combination of principal component analysis and naïve Bayes classification, with the EEG and EMG as inputs. We validated this algorithm against human-scored sleep-state scoring of data from C57BL/6J and BALB/CJ mice. We then applied a general homeostatic model to characterize the state-dependent dynamics of sleep slow-wave activity and cerebral glycolytic flux, measured as lactate concentration. Results More than 89% of epochs scored as wake or SWS by the human were scored as the same state by the machine, whether scoring in 2-second or 10-second epochs. The majority of epochs scored as REMS by the human were also scored as REMS by the machine. However, of epochs scored as REMS by the human, more than 10% were scored as SWS by the machine and 18 (10-second epochs) to 28% (2-second epochs) were scored as wake. These biases were not strain-specific, as strain differences in sleep-state timing relative to the light/dark cycle, EEG power spectral profiles, and the homeostatic dynamics of both slow waves and lactate were detected equally effectively with the automated method or the manual scoring method. Error associated with mathematical modeling of temporal dynamics of both EEG slow-wave activity and cerebral lactate either did not differ significantly when state scoring was done with automated versus visual scoring, or was reduced with automated state scoring relative to manual classification. Conclusions Machine scoring is as effective as human scoring in detecting experimental effects in rodent sleep studies. Automated scoring is an efficient alternative to visual inspection in studies of strain differences in sleep and the temporal dynamics of sleep-related physiological parameters. PMID:26366107

  3. Identifying the locations of future eruptions within large calderas: Campi Flegrei, Southern Italy.

    NASA Astrophysics Data System (ADS)

    Charlton, Danielle; Kilburn, Christopher; Sobradelo, Rosa; Edwards, Stephen

    2016-04-01

    Large calderas, with surface areas of 100 km2 or more, are among the most populated active volcanoes on Earth. New vents commonly open at locations across the caldera floor. An important goal for hazard mitigation, therefore, is to develop reliable methods for evaluating the most likely location for a future eruption. A preferred approach is to analyse statistically the distributions of previous vents. Using the Campi Flegrei caldera as a test case, we here examine the sensitivity of results to starting assumptions, notably the choice of data set for defining preferred vent locations. Situated immediately west of Naples, in southern Italy, Campi Flegrei poses a direct threat to more than 300,000 people. It has been in episodic unrest since the late 1950s. The unrest is the first since the last eruption in Campi Flegrei in 1538 and suggests that the caldera may have re-entered a state with an increased probability of an eruption. Since the most recent episode of caldera collapse 15.5 ka BP, at least 60 intra-caldera eruptions have occurred across the 150 km2 that make up the modern onshore area of Campi Flegrei. The eruptions have been concentrated within three epochs: 15.5-9.5 ka BP (Epoch 1, c. 27 eruptions), 8.6-8.2 ka BP (Epoch 2; c. 6 eruptions) and 4.8-3.8 ka BP (Epoch 3; c. 27 eruptions). Recent statistical studies of future vent locations have assumed that (1) only data from Epoch 3 are relevant to modern Campi Flegrei, and (2) repeated eruptions from the same vent can be incorporated, whether they are independent events or belong to a connected sequence of activity. We have relaxed these assumptions to investigate data from all epochs and to distinguish between independent and related eruptions from the same vent. Quadrat and nearest-neighbour statistics show that eruptions from Epochs 1 and 2 were distributed within an annulus 3-5 km around modern Pozzuoli, but that, in agreement with previous studies, eruptions occurred preferentially NE-ENE of Pozzuoli in Epoch 3. However, when related sequences of eruptions from the same vent are removed, the data show an even, annular distribution for all three epochs. The results suggest that, instead of a preference for the NE-ENE sector of Campi Flegrei, a new vent is expected to open within the established annular structure around Pozzuoli; that the probability of opening is similar in all locations within the annulus; and that, compared with Epochs 1 and 2, Epoch 3 was distinguished by a greater number of multiple eruptions from individual vents.

  4. Constraining the radio jet proper motion of the high-redshift quasar J2134-0419 at z = 4.3

    NASA Astrophysics Data System (ADS)

    Perger, Krisztina; Frey, Sándor; Gabányi, Krisztina É.; An, Tao; Britzen, Silke; Cao, Hong-Min; Cseh, Dávid; Dennett-Thorpe, Jane; Gurvits, Leonid I.; Hong, Xiao-Yu; Hook, Isobel M.; Paragi, Zsolt; Schilizzi, Richard T.; Yang, Jun; Zhang, Yingkang

    2018-06-01

    To date, PMN J2134-0419 (at a redshift z = 4.33) is the second most distant quasar known with a milliarcsecond-scale morphology permitting direct estimates of the jet proper motion. Based on two-epoch observations, we constrained its radio jet proper motion using the very long baseline interferometry (VLBI) technique. The observations were conducted with the European VLBI Network (EVN) at 5 GHz on 1999 November 26 and 2015 October 6. We imaged the central 10-pc scale radio jet emission and modelled its brightness distribution. By identifying a jet component at both epochs separated by 15.86 yr, a proper motion of μ = 0.035 ± 0.023 mas yr-1 is found. It corresponds to an apparent superluminal speed of βa = 4.1 ± 2.7 c. Relativistic beaming at both epochs suggests that the jet viewing angle with respect to the line of sight is smaller than 20°, with a minimum bulk Lorentz factor Γ = 4.3. The small value of the proper motion is in good agreement with the expectations from the cosmological interpretation of the redshift and the current cosmological model. Additionally we analysed archival Very Large Array observations of J2143-0419 and found indication of a bent jet extending to ˜30 kpc.

  5. a Robust Registration Algorithm for Point Clouds from Uav Images for Change Detection

    NASA Astrophysics Data System (ADS)

    Al-Rawabdeh, A.; Al-Gurrani, H.; Al-Durgham, K.; Detchev, I.; He, F.; El-Sheimy, N.; Habib, A.

    2016-06-01

    Landslides are among the major threats to urban landscape and manmade infrastructure. They often cause economic losses, property damages, and loss of lives. Temporal monitoring data of landslides from different epochs empowers the evaluation of landslide progression. Alignment of overlapping surfaces from two or more epochs is crucial for the proper analysis of landslide dynamics. The traditional methods for point-cloud-based landslide monitoring rely on using a variation of the Iterative Closest Point (ICP) registration procedure to align any reconstructed surfaces from different epochs to a common reference frame. However, sometimes the ICP-based registration can fail or may not provide sufficient accuracy. For example, point clouds from different epochs might fit to local minima due to lack of geometrical variability within the data. Also, manual interaction is required to exclude any non-stable areas from the registration process. In this paper, a robust image-based registration method is introduced for the simultaneous evaluation of all registration parameters. This includes the Interior Orientation Parameters (IOPs) of the camera and the Exterior Orientation Parameters (EOPs) of the involved images from all available observation epochs via a bundle block adjustment with self-calibration. Next, a semi-global dense matching technique is implemented to generate dense 3D point clouds for each epoch using the images captured in a particular epoch separately. The normal distances between any two consecutive point clouds can then be readily computed, because the point clouds are already effectively co-registered. A low-cost DJI Phantom II Unmanned Aerial Vehicle (UAV) was customised and used in this research for temporal data collection over an active soil creep area in Lethbridge, Alberta, Canada. The customisation included adding a GPS logger and a Large-Field-Of-View (LFOV) action camera which facilitated capturing high-resolution geo-tagged images in two epochs over the period of one year (i.e., May 2014 and May 2015). Note that due to the coarse accuracy of the on-board GPS receiver (e.g., +/- 5-10 m) the geo-tagged positions of the images were only used as initial values in the bundle block adjustment. Normal distances, signifying detected changes, varying from 20 cm to 4 m were identified between the two epochs. The accuracy of the co-registered surfaces was estimated by comparing non-active patches within the monitored area of interest. Since these non-active sub-areas are stationary, the computed normal distances should theoretically be close to zero. The quality control of the registration results showed that the average normal distance was approximately 4 cm, which is within the noise level of the reconstructed surfaces.

  6. Formal Uncertainty and Dispersion of Single and Double Difference Models for GNSS-Based Attitude Determination.

    PubMed

    Chen, Wen; Yu, Chao; Dong, Danan; Cai, Miaomiao; Zhou, Feng; Wang, Zhiren; Zhang, Lei; Zheng, Zhengqi

    2017-02-20

    With multi-antenna synchronized global navigation satellite system (GNSS) receivers, the single difference (SD) between two antennas is able to eliminate both satellite and receiver clock error, thus it becomes necessary to reconsider the equivalency problem between the SD and double difference (DD) models. In this paper, we quantitatively compared the formal uncertainties and dispersions between multiple SD models and the DD model, and also carried out static and kinematic short baseline experiments. The theoretical and experimental results show that under a non-common clock scheme the SD and DD model are equivalent. Under a common clock scheme, if we estimate stochastic uncalibrated phase delay (UPD) parameters every epoch, this SD model is still equivalent to the DD model, but if we estimate only one UPD parameter for all epochs or take it as a known constant, the SD (here called SD2) and DD models are no longer equivalent. For the vertical component of baseline solutions, the formal uncertainties of the SD2 model are two times smaller than those of the DD model, and the dispersions of the SD2 model are even more than twice smaller than those of the DD model. In addition, to obtain baseline solutions, the SD2 model requires a minimum of three satellites, while the DD model requires a minimum of four satellites, which makes the SD2 more advantageous in attitude determination under sheltered environments.

  7. Formal Uncertainty and Dispersion of Single and Double Difference Models for GNSS-Based Attitude Determination

    PubMed Central

    Chen, Wen; Yu, Chao; Dong, Danan; Cai, Miaomiao; Zhou, Feng; Wang, Zhiren; Zhang, Lei; Zheng, Zhengqi

    2017-01-01

    With multi-antenna synchronized global navigation satellite system (GNSS) receivers, the single difference (SD) between two antennas is able to eliminate both satellite and receiver clock error, thus it becomes necessary to reconsider the equivalency problem between the SD and double difference (DD) models. In this paper, we quantitatively compared the formal uncertainties and dispersions between multiple SD models and the DD model, and also carried out static and kinematic short baseline experiments. The theoretical and experimental results show that under a non-common clock scheme the SD and DD model are equivalent. Under a common clock scheme, if we estimate stochastic uncalibrated phase delay (UPD) parameters every epoch, this SD model is still equivalent to the DD model, but if we estimate only one UPD parameter for all epochs or take it as a known constant, the SD (here called SD2) and DD models are no longer equivalent. For the vertical component of baseline solutions, the formal uncertainties of the SD2 model are two times smaller than those of the DD model, and the dispersions of the SD2 model are even more than twice smaller than those of the DD model. In addition, to obtain baseline solutions, the SD2 model requires a minimum of three satellites, while the DD model requires a minimum of four satellites, which makes the SD2 more advantageous in attitude determination under sheltered environments. PMID:28230753

  8. Subfreezing activity of microorganisms and the potential habitability of Mars' polar regions.

    PubMed

    Jakosky, Bruce M; Nealson, Kenneth H; Bakermans, Corien; Ley, Ruth E; Mellon, Michael T

    2003-01-01

    The availability of water-ice at the surface in the Mars polar cap and within the top meter of the high-latitude regolith raises the question of whether liquid water can exist there under some circumstances and possibly support the existence of biota. We examine the minimum temperatures at which liquid water can exist at ice grain-dust grain and ice grain-ice grain contacts, the minimum subfreezing temperatures at which terrestrial organisms can grow or multiply, and the maximum temperatures that can occur in martian high-latitude and polar regions, to see if there is overlap. Liquid water can exist at grain contacts above about -20 degrees C. Measurements of growth in organisms isolated from Siberian permafrost indicate growth at -10 degrees C and metabolism at -20 degrees C. Mars polar and high-latitude temperatures rise above -20 degrees C at obliquities greater than ~40 degrees, and under some conditions rise above 0 degrees C. Thus, the environment in the Mars polar regions has overlapped habitable conditions within relatively recent epochs, and Mars appears to be on the edge of being habitable at present. The easy accessibility of the polar surface layer relative to the deep subsurface make these viable locations to search for evidence of life.

  9. A generalised optimal linear quadratic tracker with universal applications. Part 2: discrete-time systems

    NASA Astrophysics Data System (ADS)

    Ebrahimzadeh, Faezeh; Tsai, Jason Sheng-Hong; Chung, Min-Ching; Liao, Ying Ting; Guo, Shu-Mei; Shieh, Leang-San; Wang, Li

    2017-01-01

    Contrastive to Part 1, Part 2 presents a generalised optimal linear quadratic digital tracker (LQDT) with universal applications for the discrete-time (DT) systems. This includes (1) a generalised optimal LQDT design for the system with the pre-specified trajectories of the output and the control input and additionally with both the input-to-output direct-feedthrough term and known/estimated system disturbances or extra input/output signals; (2) a new optimal filter-shaped proportional plus integral state-feedback LQDT design for non-square non-minimum phase DT systems to achieve a minimum-phase-like tracking performance; (3) a new approach for computing the control zeros of the given non-square DT systems; and (4) a one-learning-epoch input-constrained iterative learning LQDT design for the repetitive DT systems.

  10. Coordinated neuronal activity enhances corticocortical communication

    PubMed Central

    Zandvakili, Amin; Kohn, Adam

    2015-01-01

    Summary Relaying neural signals between cortical areas is central to cognition and sensory processing. The temporal coordination of activity in a source population has been suggested to determine corticocortical signaling efficacy, but others have argued that coordination is functionally irrelevant. We reasoned that if coordination significantly influenced signaling, spiking in downstream networks should be preceded by transiently elevated coordination in a source population. We developed a metric to quantify network coordination in brief epochs, and applied it to simultaneous recordings of neuronal populations in cortical areas V1 and V2 of the macaque monkey. Spiking in the input layers of V2 was preceded by brief epochs of elevated V1 coordination, but this was not the case in other layers of V2. Our results indicate that V1 coordination influences its signaling to direct downstream targets, but that coordinated V1 epochs do not propagate through multiple downstream networks as in some corticocortical signaling schemes. PMID:26291164

  11. RADIO ASTROMETRY OF THE CLOSE ACTIVE BINARY HR 5110

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abbuhl, E.; Mutel, R. L.; Lynch, C.

    2015-09-20

    The close active binary HR 5110 was observed at six epochs over 26 days using a global very long baseline interferometry array at 15.4 GHz. We used phase referencing to determine the position of the radio centroid at each epoch with an uncertainty significantly smaller than the component separation. After correcting for proper motion and parallax, we find that the centroid locations of all six epochs have barycenter separations consistent with an emission source located on the KIV secondary, and not in an interaction region between the stars or on the F primary. We used a homogeneous power-law gyrosynchrotron emissionmore » model to reproduce the observed flux densities and fractional circular polarization. The resulting ranges of mean magnetic field strength and relativistic electron densities are of the order of 10 G and 10{sup 5} cm{sup −3}, respectively, in the source region.« less

  12. Solar Cycle Dependence of the Diurnal Anisotropy of 0.6 TeV Cosmic-ray Intensity Observed with the Matsushiro Underground Muon Detector

    NASA Astrophysics Data System (ADS)

    Munakata, K.; Mizoguchi, Y.; Kato, C.; Yasue, S.; Mori, S.; Takita, M.; Kóta, J.

    2010-04-01

    We analyze the temporal variation of the diurnal anisotropy of sub-TeV cosmic-ray intensity observed with the Matsushiro (Japan) underground muon detector over two full solar activity cycles in 1985-2008. We find an anisotropy component in the solar diurnal anisotropy superimposed on the Compton-Getting anisotropy due to Earth's orbital motion around the Sun. The phase of this additional anisotropy is almost constant at ~15:00 local solar time corresponding to the direction perpendicular to the average interplanetary magnetic field at Earth's orbit, while the amplitude varies between a maximum (0.043% ± 0.002%) and minimum (~0.008% ± 0.002%) in a clear correlation with the solar activity. We find a significant time lag between the temporal variations of the amplitude and the sunspot number (SSN) and obtain the best correlation coefficient of +0.74 with the SSN delayed for 26 months. We suggest that this anisotropy might be interpreted in terms of the energy change due to the solar-wind-induced electric field expected for galactic cosmic rays (GCRs) crossing the wavy neutral sheet. The average amplitude of the sidereal diurnal variation over the entire period is 0.034% ± 0.003%, which is roughly one-third of the amplitude reported from air shower and deep-underground muon experiments monitoring multi-TeV GCR intensity suggesting a significant attenuation of the anisotropy due to the solar modulation. We find, on the other hand, only a weak positive correlation between the sidereal diurnal anisotropy and the solar activity cycle in which the amplitude in the "active" solar activity epoch is about twice the amplitude in the "quiet" solar activity epoch. This implies that only one-fourth of the total attenuation varies in correlation with the solar activity cycle and/or the solar magnetic cycle. We finally examine the temporal variation of the "single-band valley depth" (SBVD) quoted by the Milagro experiment and, in contrast with recent Milagro's report, we find no steady increase in the Matsushiro observations in a seven-year period between 2000 and 2007. We suggest, therefore, that the steady increase of the SBVD reported by the Milagro experiment is not caused by the decreasing solar modulation in the declining phase of the 23rd solar activity cycle.

  13. Environmental Profile of a Community's Health (EPOCH): An Instrument to Measure Environmental Determinants of Cardiovascular Health in Five Countries

    PubMed Central

    Chow, Clara K.; Lock, Karen; Madhavan, Manisha; Corsi, Daniel J.; Gilmore, Anna B.; Subramanian, S. V.; Li, Wei; Swaminathan, Sumathi; Lopez-Jaramillo, Patricio; Avezum, Alvaro; Lear, Scott A.; Dagenais, Gilles; Teo, Koon; McKee, Martin; Yusuf, Salim

    2010-01-01

    Background The environment in which people live is known to be important in influencing diet, physical activity, smoking, psychosocial and other risk factors for cardiovascular (CV) disease. However no instrument exists that evaluates communities for these multiple environmental factors and is suitable for use across different communities, regions and countries. This report describes the design and reliability of an instrument to measure environmental determinants of CV risk factors. Method/Principal Findings The Environmental Profile of Community Health (EPOCH) instrument comprises two parts: (I) an assessment of the physical environment, and (II) an interviewer-administered questionnaire to collect residents' perceptions of their community. We examined the inter-rater reliability amongst 3 observers from each region of the direct observation component of the instrument (EPOCH I) in 93 rural and urban communities in 5 countries (Canada, Colombia, Brazil, China and India). Data collection using the EPOCH instrument was feasible in all communities. Reliability of the instrument was excellent (Intraclass Correlation Coefficient - ICC>0.75) for 24 of 38 items and fair to good (ICC 0.4–0.75) for 14 of 38 items. Conclusion This report shows data collection with the EPOCH instrument is feasible and direct observation of community measures reliable. The EPOCH instrument will enable further research on environmental determinants of health for population studies from a broad range of settings. PMID:21170320

  14. Galactic wind X-ray heating of the intergalactic medium during the Epoch of Reionization

    NASA Astrophysics Data System (ADS)

    Meiksin, Avery; Khochfar, Sadegh; Paardekooper, Jan-Pieter; Dalla Vecchia, Claudio; Kohn, Saul

    2017-11-01

    The diffuse soft X-ray emissivity from galactic winds is computed during the Epoch of Reionization (EoR). We consider two analytic models, a pressure-driven wind and a superbubble model, and a 3D cosmological simulation including gas dynamics from the First Billion Years (FiBY) project. The analytic models are normalized to match the diffuse X-ray emissivity of star-forming galaxies in the nearby Universe. The cosmological simulation uses physically motivated star formation and wind prescriptions, and includes radiative transfer corrections. The models and the simulation all are found to produce sufficient heating of the intergalactic medium to be detectable by current and planned radio facilities through 21 cm measurements during the EoR. While the analytic models predict a 21 cm emission signal relative to the cosmic microwave backgroundsets in by ztrans ≃ 8-10, the predicted signal in the FiBY simulation remains in absorption until reionization completes. The 21 cm absorption differential brightness temperature reaches a minimum of ΔT ≃ -130 to -200 mK, depending on model. Allowing for additional heat from high-mass X-ray binaries pushes the transition to emission to ztrans ≃ 10-12, with shallower absorption signatures having a minimum of ΔT ≃ -110 to -140 mK. The 21 cm signal may be a means of distinguishing between the wind models, with the superbubble model favouring earlier reheating. While an early transition to emission may indicate X-ray binaries dominate the reheating, a transition to emission as early as ztrans > 12 would suggest the presence of additional heat sources.

  15. Role of multisensory stimuli in vigilance enhancement- a single trial event related potential study.

    PubMed

    Abbasi, Nida Itrat; Bodala, Indu Prasad; Bezerianos, Anastasios; Yu Sun; Al-Nashash, Hasan; Thakor, Nitish V

    2017-07-01

    Development of interventions to prevent vigilance decrement has important applications in sensitive areas like transportation and defence. The objective of this work is to use multisensory (visual and haptic) stimuli for cognitive enhancement during mundane tasks. Two different epoch intervals representing sensory perception and motor response were analysed using minimum variance distortionless response (MVDR) based single trial ERP estimation to understand the performance dependency on both factors. Bereitschaftspotential (BP) latency L3 (r=0.6 in phase 1 (visual) and r=0.71 in phase 2 (visual and haptic)) was significantly correlated with reaction time as compared to that of sensory ERP latency L2 (r=0.1 in both phase 1 and phase 2). This implies that low performance in monotonous tasks is predominantly dependent on the prolonged neural interaction with the muscles to initiate movement. Further, negative relationship was found between the ERP latencies related to sensory perception and Bereitschaftspotential (BP) and occurrence of epochs when multisensory cues are provided. This means that vigilance decrement is reduced with the help of multisensory stimulus presentation in prolonged monotonous tasks.

  16. Classification of epilepsy types through global network analysis of scalp electroencephalograms

    NASA Astrophysics Data System (ADS)

    Lee, Uncheol; Kim, Seunghwan; Jung, Ki-Young

    2006-04-01

    Epilepsy is a dynamic disease in which self-organization and emergent structures occur dynamically at multiple levels of neuronal integration. Therefore, the transient relationship within multichannel electroencephalograms (EEGs) is crucial for understanding epileptic processes. In this paper, we show that the global relationship within multichannel EEGs provides us with more useful information in classifying two different epilepsy types than pairwise relationships such as cross correlation. To demonstrate this, we determine the global network structure within channels of the scalp EEG based on the minimum spanning tree method. The topological dissimilarity of the network structures from different types of temporal lobe epilepsy is described in the form of the divergence rate and is computed for 11 patients with left (LTLE) and right temporal lobe epilepsy (RTLE). We find that patients with LTLE and RTLE exhibit different large scale network structures, which emerge at the epoch immediately before the seizure onset, not in the preceding epochs. Our results suggest that patients with the two different epilepsy types display distinct large scale dynamical networks with characteristic epileptic network structures.

  17. Nonlinear Recurrent Dynamics and Long-Term Nonstationarities in EEG Alpha Cortical Activity: Implications for Choosing Adequate Segment Length in Nonlinear EEG Analyses.

    PubMed

    Cerquera, Alexander; Vollebregt, Madelon A; Arns, Martijn

    2018-03-01

    Nonlinear analysis of EEG recordings allows detection of characteristics that would probably be neglected by linear methods. This study aimed to determine a suitable epoch length for nonlinear analysis of EEG data based on its recurrence rate in EEG alpha activity (electrodes Fz, Oz, and Pz) from 28 healthy and 64 major depressive disorder subjects. Two nonlinear metrics, Lempel-Ziv complexity and scaling index, were applied in sliding windows of 20 seconds shifted every 1 second and in nonoverlapping windows of 1 minute. In addition, linear spectral analysis was carried out for comparison with the nonlinear results. The analysis with sliding windows showed that the cortical dynamics underlying alpha activity had a recurrence period of around 40 seconds in both groups. In the analysis with nonoverlapping windows, long-term nonstationarities entailed changes over time in the nonlinear dynamics that became significantly different between epochs across time, which was not detected with the linear spectral analysis. Findings suggest that epoch lengths shorter than 40 seconds neglect information in EEG nonlinear studies. In turn, linear analysis did not detect characteristics from long-term nonstationarities in EEG alpha waves of control subjects and patients with major depressive disorder patients. We recommend that application of nonlinear metrics in EEG time series, particularly of alpha activity, should be carried out with epochs around 60 seconds. In addition, this study aimed to demonstrate that long-term nonlinearities are inherent to the cortical brain dynamics regardless of the presence or absence of a mental disorder.

  18. Postinflationary Higgs relaxation and the origin of matter-antimatter asymmetry.

    PubMed

    Kusenko, Alexander; Pearce, Lauren; Yang, Louis

    2015-02-13

    The recent measurement of the Higgs boson mass implies a relatively slow rise of the standard model Higgs potential at large scales, and a possible second minimum at even larger scales. Consequently, the Higgs field may develop a large vacuum expectation value during inflation. The relaxation of the Higgs field from its large postinflationary value to the minimum of the effective potential represents an important stage in the evolution of the Universe. During this epoch, the time-dependent Higgs condensate can create an effective chemical potential for the lepton number, leading to a generation of the lepton asymmetry in the presence of some large right-handed Majorana neutrino masses. The electroweak sphalerons redistribute this asymmetry between leptons and baryons. This Higgs relaxation leptogenesis can explain the observed matter-antimatter asymmetry of the Universe even if the standard model is valid up to the scale of inflation, and any new physics is suppressed by that high scale.

  19. INFERRING THE STRUCTURE OF THE SOLAR CORONA AND INNER HELIOSPHERE DURING THE MAUNDER MINIMUM USING GLOBAL THERMODYNAMIC MAGNETOHYDRODYNAMIC SIMULATIONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riley, Pete; Lionello, Roberto; Linker, Jon A., E-mail: pete@predsci.com, E-mail: lionel@predsci.com, E-mail: linkerj@predsci.com

    Observations of the Sun’s corona during the space era have led to a picture of relatively constant, but cyclically varying solar output and structure. Longer-term, more indirect measurements, such as from {sup 10}Be, coupled by other albeit less reliable contemporaneous reports, however, suggest periods of significant departure from this standard. The Maunder Minimum was one such epoch where: (1) sunspots effectively disappeared for long intervals during a 70 yr period; (2) eclipse observations suggested the distinct lack of a visible K-corona but possible appearance of the F-corona; (3) reports of aurora were notably reduced; and (4) cosmic ray intensities atmore » Earth were inferred to be substantially higher. Using a global thermodynamic MHD model, we have constructed a range of possible coronal configurations for the Maunder Minimum period and compared their predictions with these limited observational constraints. We conclude that the most likely state of the corona during—at least—the later portion of the Maunder Minimum was not merely that of the 2008/2009 solar minimum, as has been suggested recently, but rather a state devoid of any large-scale structure, driven by a photospheric field composed of only ephemeral regions, and likely substantially reduced in strength. Moreover, we suggest that the Sun evolved from a 2008/2009-like configuration at the start of the Maunder Minimum toward an ephemeral-only configuration by the end of it, supporting a prediction that we may be on the cusp of a new grand solar minimum.« less

  20. Evoked potentials in final epoch of self-initiated hand movement: A study in patients with depth electrodes.

    PubMed

    Kukleta, Miloslav; Damborská, Alena; Turak, Baris; Louvel, Jacques

    2017-07-01

    Comparison between the intended and performed motor action can be expected to occur in the final epoch of a voluntary movement. In search for electrophysiological correlates of this mental process the purpose of the current study was to identify intracerebral sites activated in final epoch of self-paced voluntary movement. Intracerebral EEG was recorded from 235 brain regions of 42 epileptic patients who performed self-paced voluntary movement task. Evoked potentials starting at 0 to 243ms after the peak of averaged, rectified electromyogram were identified in 21 regions of 13 subjects. The mean amplitude value of these late movement potentials (LMP) was 56.4±27.5μV. LMPs were observed in remote regions of mesiotemporal structures, cingulate, frontal, temporal, parietal, and occipital cortices. Closely before the LMP onset, a significant increase of phase synchronization was observed in all EEG record pairs in 9 of 10 examined subjects; p<0.001, Mann-Whitney U test. In conclusion, mesiotemporal structures, cingulate, frontal, temporal, parietal, and occipital cortices seem to represent integral functionally linked parts of network activated in final epoch of self-paced voluntary movement. Activation of this large-scale neuronal network was suggested to reflect a comparison process between the intended and actually performed motor action. Our results contribute to better understanding of neural mechanisms underlying goal-directed behavior crucial for creation of agentive experience. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Evidence that one is more likely to see the aurora near Moscow than near Ann Arbor

    NASA Astrophysics Data System (ADS)

    Liemohn, Michael; Immel, Thomas; Katus, Roxanne

    We present a superposed epoch analysis of solar wind drivers and geomagnetic index responses during magnetic storms, categorized as a function of universal time (UT) of the storm peak, to investigate the dependency of storm intensity on UT. Storms with Dst minimum less than - 100 nT were identified in the 1970 - 2012 era (totaling 310 events), covering four solar cycles. The storms were classified into 6 groups based on the UT of the minimum Dst (36 to 82 events per bin), then each grouping was superposed on a timeline that aligns the time of the minimum Dst. Fifteen different quantities were considered, seven solar wind parameters and eight activity indices derived from ground-based magnetometers. Statistical analyses of the superposed means against each other (between the different UT groupings) were conducted to determine the mathematical significance of similarities and differences in the time series plots. It was found that most of the solar wind parameters have essentially no significant difference between the UT groupings, as expected. The exception is solar wind velocity, which appears to be bifurcated into two levels with three of the UT groupings systematically faster than the other three (although, interestingly, not three consecutive UT bins). The geomagnetic activity indices, however, all show statistically significant differences with UT during the main phase and/or early recovery phase. Specifically, the 16, 20, and 00 UT groupings are stronger storms than those in the other UT bins. That is, storms are stronger when the Asian sector is on the nightside (American sector on the dayside) during the main phase. An inference from these findings, therefore, is that one is more likely to see the aurora near Moscow in Russia than near Ann Arbor, Michigan in the United States, even though these two cities have very similar magnetic latitudes (52 degrees).

  2. Diagnostic thresholds for quantitative REM sleep phasic burst duration, phasic and tonic muscle activity, and REM atonia index in REM sleep behavior disorder with and without comorbid obstructive sleep apnea.

    PubMed

    McCarter, Stuart J; St Louis, Erik K; Duwell, Ethan J; Timm, Paul C; Sandness, David J; Boeve, Bradley F; Silber, Michael H

    2014-10-01

    We aimed to determine whether phasic burst duration and conventional REM sleep without atonia (RSWA) methods could accurately diagnose REM sleep behavior disorder (RBD) patients with comorbid OSA. We visually analyzed RSWA phasic burst durations, phasic, "any," and tonic muscle activity by 3-s mini-epochs, phasic activity by 30-s (AASM rules) epochs, and conducted automated REM atonia index (RAI) analysis. Group RSWA metrics were analyzed and regression models fit, with receiver operating characteristic (ROC) curves determining the best diagnostic cutoff thresholds for RBD. Both split-night and full-night polysomnographic studies were analyzed. N/A. Parkinson disease (PD)-RBD (n = 20) and matched controls with (n = 20) and without (n = 20) OSA. N/A. All mean RSWA phasic burst durations and muscle activities were higher in PD-RBD patients than controls (P < 0.0001), and RSWA associations with PD-RBD remained significant when adjusting for age, gender, and REM AHI (P < 0.0001). RSWA muscle activity (phasic, "any") cutoffs for 3-s mini-epoch scorings were submentalis (SM) (15.5%, 21.6%), anterior tibialis (AT) (30.2%, 30.2%), and combined SM/AT (37.9%, 43.4%). Diagnostic cutoffs for 30-s epochs (AASM criteria) were SM 2.8%, AT 11.3%, and combined SM/AT 34.7%. Tonic muscle activity cutoff of 1.2% was 100% sensitive and specific, while RAI (SM) cutoff was 0.88. Phasic muscle burst duration cutoffs were: SM (0.65) and AT (0.79) seconds. Combining phasic burst durations with RSWA muscle activity improved sensitivity and specificity of RBD diagnosis. This study provides evidence for REM sleep without atonia diagnostic thresholds applicable in Parkinson disease-REM sleep behavior disorder (PD-RBD) patient populations with comorbid OSA that may be useful toward distinguishing PD-RBD in typical outpatient populations. © 2014 Associated Professional Sleep Societies, LLC.

  3. Using recurrence plot for determinism analysis of EEG recordings in genetic absence epilepsy rats.

    PubMed

    Ouyang, Gaoxiang; Li, Xiaoli; Dang, Chuangyin; Richards, Douglas A

    2008-08-01

    Understanding the transition of brain activity towards an absence seizure is a challenging task. In this paper, we use recurrence quantification analysis to indicate the deterministic dynamics of EEG series at the seizure-free, pre-seizure and seizure states in genetic absence epilepsy rats. The determinism measure, DET, based on recurrence plot, was applied to analyse these three EEG datasets, each dataset containing 300 single-channel EEG epochs of 5-s duration. Then, statistical analysis of the DET values in each dataset was carried out to determine whether their distributions over the three groups were significantly different. Furthermore, a surrogate technique was applied to calculate the significance level of determinism measures in EEG recordings. The mean (+/-SD) DET of EEG was 0.177+/-0.045 in pre-seizure intervals. The DET values of pre-seizure EEG data are significantly higher than those of seizure-free intervals, 0.123+/-0.023, (P<0.01), but lower than those of seizure intervals, 0.392+/-0.110, (P<0.01). Using surrogate data methods, the significance of determinism in EEG epochs was present in 25 of 300 (8.3%), 181 of 300 (60.3%) and 289 of 300 (96.3%) in seizure-free, pre-seizure and seizure intervals, respectively. Results provide some first indications that EEG epochs during pre-seizure intervals exhibit a higher degree of determinism than seizure-free EEG epochs, but lower than those in seizure EEG epochs in absence epilepsy. The proposed methods have the potential of detecting the transition between normal brain activity and the absence seizure state, thus opening up the possibility of intervention, whether electrical or pharmacological, to prevent the oncoming seizure.

  4. Have We Entered a 21st Century Prolonged Minimum of Solar Activity? Updated Implications of a 1987 Prediction

    NASA Astrophysics Data System (ADS)

    Shirley, James H.

    2009-05-01

    Fairbridge and Shirley (1987) predicted that a new prolonged minimum of solar activity would be underway by the year 2013 (Solar Physics 110, 191). While it is much too early to tell if this prediction will be fully realized, recent observations document a striking reduction in the Sun's general level of activity. While other forecasts of reduced future activity levels on decadal time scales have appeared, the Fairbridge-Shirley (FS) prediction is unique in pinpointing the current epoch. We are unaware of any forecast method that shows a better correspondence with the actual behavior of the Sun to this point. The FS prediction was based on the present-day recurrence of two physical indicators that were correlated in time with the occurrence of the Wolf, Sporer, and Maunder Minima. The amplitude of the inertial revolution of the axis of symmetry of the Sun's orbital motion about the solar system barycenter, and the direction in space of that axis, each bear a relationship to the occurrence of the prolonged minima of the historic record. The FS prediction appeared before the importance of solar meridional flows was generally appreciated, and before the existence and role of the tachocline was suspected. We will update and restate some of the physical implications of the FS results, along with those of some more recent investigations, particularly with reference to orbit-spin coupling hypotheses (Shirley, 2006: M.N.R.A.S. 368, 280). New investigations combining and integrating modern dynamo models with physical solutions describing key aspects of the variability of the solar motion may lead to significant advances in our ability to forecast future changes in the Sun. Acknowledgement: This work was supported by the resources of the author. No part of this work was performed at the Jet Propulsion Laboratory under a contract from NASA.

  5. Second Epoch VLBA Calibrator Survey Observations - VCS-II

    NASA Technical Reports Server (NTRS)

    Gordon, David; Jacobs, Christopher; Beasley, Anthony; Peck, Alison; Gaume, Ralph; Charlot, Patrick; Fey, Alan; Ma, Chopo; Titov, Oleg; Boboltz, David

    2016-01-01

    Six very successful VLBA calibrator survey campaigns were run between 1994 and 2007 to build up a large list of compact radio sources with positions precise enough for use as VLBI phase reference calibrators. We report on the results of a second epoch VLBA Calibrator Survey campaign (VCS-II) in which 2400 VCS sources were re-observed at X and S bands in order to improve the upcoming third realization of the International Celestial Reference Frame (ICRF3) as well as to improve their usefulness as VLBI phase reference calibrators. In this survey, some 2062 previously detected sources and 324 previously undetected sources were detected and revised positions are presented. Average position uncertainties for the reobserved sources were reduced from 1.14 and 1.98 mas to 0.24 and 0.41 mas in RA and Declination, respectively, or by nearly a factor of 5. Minimum detected flux values were approximately 15 and 28 mJy in X and S bands, respectively, and median total fluxes are approximately 230 and 280 mJy. The vast majority of these sources are flat-spectrum sources, with approximately 82% having spectral indices greater than -0.5.

  6. Second Epoch VLBA Calibrator Survey Observations: VCS-II

    NASA Astrophysics Data System (ADS)

    Gordon, David; Jacobs, Christopher; Beasley, Anthony; Peck, Alison; Gaume, Ralph; Charlot, Patrick; Fey, Alan; Ma, Chopo; Titov, Oleg; Boboltz, David

    2016-06-01

    Six very successful Very Long Baseline Array (VLBA) calibrator survey campaigns were run between 1994 and 2007 to build up a large list of compact radio sources with positions precise enough for use as very long baseline interferometry (VLBI) phase reference calibrators. We report on the results of a second epoch VLBA Calibrator Survey campaign (VCS-II) in which 2400 VCS sources were re-observed in the X and S bands in order to improve the upcoming third realization of the International Celestial Reference Frame (ICRF3) as well as to improve their usefulness as VLBI phase reference calibrators. In this survey, some 2062 previously detected sources and 324 previously undetected sources were detected and revised positions are presented. Average position uncertainties for the re-observed sources were reduced from 1.14 and 1.98 mas to 0.24 and 0.41 mas in R.A. and decl., respectively, or by nearly a factor of 5. Minimum detected flux values were approximately 15 and 28 mJy in the X and S bands, respectively, and median total fluxes are approximately 230 and 280 mJy. The vast majority of these sources are flat-spectrum sources, with ˜82% having spectral indices greater than -0.5.

  7. Improving activity recognition using a wearable barometric pressure sensor in mobility-impaired stroke patients.

    PubMed

    Massé, Fabien; Gonzenbach, Roman R; Arami, Arash; Paraschiv-Ionescu, Anisoara; Luft, Andreas R; Aminian, Kamiar

    2015-08-25

    Stroke survivors often suffer from mobility deficits. Current clinical evaluation methods, including questionnaires and motor function tests, cannot provide an objective measure of the patients' mobility in daily life. Physical activity performance in daily-life can be assessed using unobtrusive monitoring, for example with a single sensor module fixed on the trunk. Existing approaches based on inertial sensors have limited performance, particularly in detecting transitions between different activities and postures, due to the inherent inter-patient variability of kinematic patterns. To overcome these limitations, one possibility is to use additional information from a barometric pressure (BP) sensor. Our study aims at integrating BP and inertial sensor data into an activity classifier in order to improve the activity (sitting, standing, walking, lying) recognition and the corresponding body elevation (during climbing stairs or when taking an elevator). Taking into account the trunk elevation changes during postural transitions (sit-to-stand, stand-to-sit), we devised an event-driven activity classifier based on fuzzy-logic. Data were acquired from 12 stroke patients with impaired mobility, using a trunk-worn inertial and BP sensor. Events, including walking and lying periods and potential postural transitions, were first extracted. These events were then fed into a double-stage hierarchical Fuzzy Inference System (H-FIS). The first stage processed the events to infer activities and the second stage improved activity recognition by applying behavioral constraints. Finally, the body elevation was estimated using a pattern-enhancing algorithm applied on BP. The patients were videotaped for reference. The performance of the algorithm was estimated using the Correct Classification Rate (CCR) and F-score. The BP-based classification approach was benchmarked against a previously-published fuzzy-logic classifier (FIS-IMU) and a conventional epoch-based classifier (EPOCH). The algorithm performance for posture/activity detection, in terms of CCR was 90.4 %, with 3.3 % and 5.6 % improvements against FIS-IMU and EPOCH, respectively. The proposed classifier essentially benefits from a better recognition of standing activity (70.3 % versus 61.5 % [FIS-IMU] and 42.5 % [EPOCH]) with 98.2 % CCR for body elevation estimation. The monitoring and recognition of daily activities in mobility-impaired stoke patients can be significantly improved using a trunk-fixed sensor that integrates BP, inertial sensors, and an event-based activity classifier.

  8. Mount Etna: 3-D and 4-D structure using seismic tomography

    NASA Astrophysics Data System (ADS)

    Nunn, C.; Julian, B. R.; Foulger, G. R.; Patanè, D.; Ibáñez, J. M.; Briole, P.; Mhanna, N.

    2015-12-01

    We investigate the time-varying structure of Etna, an active stratovolcano in eastern Sicily, using seismic tomography. In volcanic systems, it is thought that the presence of fluids, cracks and pressurized gases can rapidly and drastically change the elastic properties of the host rocks. Recent work suggests that changes beneath Etna are detectable with seismic methods, and that these changes can be linked to volcanic activity. Temporal changes to Earth structure are commonly investigated by carrying out separate tomographic inversions for different epochs. However, repeated inversions of the same area are expected to vary, even if the structure itself does not change. This is due to variations in the seismic ray distribution and to observational errors. Potentially, changes between epochs which are due to experimental limitations can be misinterpreted as changes to the structure of the volcano. Consequently, we use a new tomographic program, TOMO4D, that inverts multiple data sets simultaneously [Julian & Foulger, Time-dependent seismic tomography, GJI, 2010]. This code imposes constraints which minimise the differences calculated between two epochs. The remaining structural variations are thus truly required to fit the data, and reflect changes which almost certainly exist between the two epochs. We have selected and relocated ~400 local earthquakes with at least 5 P and 5 S observations. They cover a period which includes several eruptions, from 1st November 2000 to 31st December 2006. We divide our data into different epochs and invert two epochs simultaneously. The models show a seismically fast central region, surrounded by a slower outer region. This suggests a central system of dykes or sills surrounded by volcanic sediments and country rock. At depths of 0-4 km below sea level the seismically fast region is not below the summit crater but is offset to the southwest. By monitoring the changes to the elastic parameters of the host rocks we observe temporal changes within the volcano. The technique has potential for long-term volcano monitoring and hazard assessment since it could be applied to monitoring changes from month to month.

  9. Relationship between lunar tidal enhancements in the equatorial electrojet and tropospheric eddy heat flux during stratospheric sudden warmings

    NASA Astrophysics Data System (ADS)

    Siddiqui, T. A.; Yamazaki, Y.; Stolle, C.; Lühr, H.; Matzka, J.

    2017-12-01

    A number of studies in recent years have reported about the lunar tidal enhancements in the equatorial electrojet (EEJ) from ground- and space-based magnetometer measurements during stratospheric sudden warming (SSW) events. In this study, we make use of the ground magnetometer recordings at Huancayo observatory in Peru for the years 1978 - 2013 to derive a relationship between the lunar tidal enhancements in the EEJ and tropospheric eddy heat fluxes at 100 hPa during the SSW events. Tropospheric eddy heat fluxes are used to quantify the amount of wave activity entering the stratosphere. Anomalously large upward wave activity is known to precede the polar vortex breakdown during SSWs. We make use of the superposed epoch analysis method to determine the temporal relations between lunar tidal enhancements and eddy heat flux anomalies during SSWs, in order to demonstrate the causal relationship between these two phenomena. We also compare the lunar tidal enhancements and eddy heat flux anomalies for vortex split and for vortex displaced SSWs. It is found that larger lunar tidal enhancements are recorded for vortex split events, as compared to vortex displaced events. This confirms earlier observation; larger heat flux anomalies are recorded during vortex split SSW events than the heat flux anomalies during vortex displaced SSW events. Further, the temporal relations of lunar tidal enhancements in the EEJ have been compared separately for both the QBO phases and with the phases of the moon with respect to the central epoch of SSWs by means of the superposed epoch analysis approach. The EEJ lunar tidal enhancements in the east phase of QBO are found to be larger than the lunar tidal enhancements in the west phase of QBO. The phase of moon relative to the central SSW epoch also affects the lunar tidal enhancement in the EEJ. It is found that the lunar tidal enhancements are significantly larger when the day of new or full moon lies near the central SSW epoch, as compared to cases when new or full moon occur further away from the central SSW epoch.

  10. Early-Childhood Neurodevelopmental Outcomes Are Not Improving for Infants Born at <25 Weeks' Gestational Age

    PubMed Central

    Kendrick, Douglas E.; Wilson-Costello, Deanne E.; Das, Abhik; Bell, Edward F.; Vohr, Betty R.; Higgins, Rosemary D.

    2011-01-01

    OBJECTIVE: We compared neurodevelopmental outcomes at 18 to 22 months' corrected age of infants born with extremely low birth weight at an estimated gestational age of <25 weeks during 2 periods: 1999–2001 (epoch 1) and 2002–2004 (epoch 2). PATIENTS AND METHODS: We conducted a multicenter, retrospective analysis of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Perinatal and neonatal variables and outcomes were compared between epochs. Neurodevelopmental outcomes at 18 to 22 months' corrected age were evaluated with neurologic exams and Bayley Scales of Infant Development II. Logistic regression analyses determined the independent risk of epoch for adverse outcomes. RESULTS: Infant survival was similar between epochs (epoch 1, 35.4%, vs epoch 2, 32.3%; P = .09). A total of 411 of 452 surviving infants in epoch 1 and 405 of 438 surviving infants in epoch 2 were evaluated at 18 to 22 months' corrected age. Cesarean delivery (P = .03), surgery for patent ductus arteriosus (P = .004), and late sepsis (P = .01) were more common in epoch 2, but postnatal steroid use was dramatically reduced (63.5% vs 32.8%; P < .0001). Adverse outcomes at 18 to 22 months' corrected age were common in both epochs. Moderate-to-severe cerebral palsy was diagnosed in 11.1% of surviving infants in epoch 1 and 14.9% in epoch 2 (adjusted odds ratio [OR]: 1.52 [95% confidence interval (CI): 0.86–2.71]; P = .15), the Mental Developmental Index was <70 in 44.9% in epoch 1 and 51% in epoch 2 (OR: 1.30 [95% CI: 0.91–1.87]; P = .15), and neurodevelopmental impairment was diagnosed in 50.1% of surviving infants in epoch 1 and 58.7% in epoch 2 (OR: 1.4 [95% CI: 0.98–2.04]; P = .07). CONCLUSIONS: Early-childhood outcomes for infants born at <25 weeks' estimated gestational age were unchanged between the 2 periods. PMID:21187312

  11. Use of Apollo 17 Epoch Neutron Spectrum as a Benchmark in Testing LEND Collimated Sensor

    NASA Technical Reports Server (NTRS)

    Chin, Gordon; Sagdeev, R.; Milikh, G.

    2011-01-01

    The Apollo 17 neutron experiment LPNE provided a unique set of data on production of neutrons in the Lunar soil bombarded by Galactic Cosmic Rays (GCR). It serves as valuable "ground-truth" in the age of orbital remote sensing. We used the neutron data attributed to Apollo 17 epoch as a benchmark for testing the LEND's collimated sensor, as introduced by the geometry of collimator and efficiency of He3 counters. The latter is defined by the size of gas counter and pressure inside it. The intensity and energy spectrum of neutrons escaping the lunar surface are dependent on incident flux of Galactic Cosmic Rays (GCR) whose variability is associated with Solar Cycle and its peculiarities. We obtain first the share of neutrons entering through the field of view of collimator as a fraction of the total neutron flux by using the angular distribution of neutron exiting the Moon described by our Monte Carlo code. We computed next the count rate of the 3He sensor by using the neutron energy spectrum from McKinney et al. [JGR, 2006] and by consider geometry and gas pressure of the LEND sensor. Finally the neutron count rate obtained for the Apollo 17 epoch characterized by intermediate solar activity was adjusted to the LRO epoch characterized by low solar activity. It has been done by taking into account solar modulation potential, which affects the GCR flux, and in turn changes the neutron albedo flux.

  12. The dynamics of the Jovian White Ovals and the Great Red Spot in the presence of the East-West zonal flow

    NASA Astrophysics Data System (ADS)

    Youssef, Ashraf

    We characterize the history of Jupiter's three White Ovals as four distinct epochs: Formation (1939-41), Kármán Vortex Street (1941-94), Pre- Merger (1994-97), and Merger (1997-98). We use a quasi-geostrophic model. During Formation, the three anti-cyclonic White Ovals were created through the break up of a band of clouds that circled the planet at ~34°S. The Kármán Vortex Street Epoch is marked by longitudinal oscillations of the vortices. We show that for the White Ovals to oscillate and not merge, they must be in a Kármán vortex street, where the row of White Ovals is staggered with a row of cyclones slightly to their north. The Pre- Merger Epoch is marked by the White Ovals travelling as a closely spaced group. We found that if the eastern jet to the south of the row of White Ovals is a sharp gradient in background potential vorticity, it forms a Rossby wave that traps the White Ovals. During the Merger Epoch, in early 1998, the trapped White Ovals BC and DE approached a cyclone to their east, and they merged. Our numerical simulations show that the cyclone between BC and DE was forced to exchange places with DE for the merger to occur. We determine the energy requirements for exchange. The numerical simulations of the Great Red Spot (GRS) cannot reproduce its quiet central region unless it too is trapped by a Rossby wave. In order for the GRS to be a high speed circumferential jet surrounding a quiet center, it must be a hollow vortex with a minimum of potential vorticity at the center and a maximum at the edge. The GRS with sufficient hollowness is unstable to fragmentation and redistribution of its potential vorticity to a distribution which is peaked at the center rather than hollow. If the GRS rests in the trough of a Rossby wave, we show that a sufficiently hollow GRS is stabilized.

  13. A system for automatic artifact removal in ictal scalp EEG based on independent component analysis and Bayesian classification.

    PubMed

    LeVan, P; Urrestarazu, E; Gotman, J

    2006-04-01

    To devise an automated system to remove artifacts from ictal scalp EEG, using independent component analysis (ICA). A Bayesian classifier was used to determine the probability that 2s epochs of seizure segments decomposed by ICA represented EEG activity, as opposed to artifact. The classifier was trained using numerous statistical, spectral, and spatial features. The system's performance was then assessed using separate validation data. The classifier identified epochs representing EEG activity in the validation dataset with a sensitivity of 82.4% and a specificity of 83.3%. An ICA component was considered to represent EEG activity if the sum of the probabilities that its epochs represented EEG exceeded a threshold predetermined using the training data. Otherwise, the component represented artifact. Using this threshold on the validation set, the identification of EEG components was performed with a sensitivity of 87.6% and a specificity of 70.2%. Most misclassified components were a mixture of EEG and artifactual activity. The automated system successfully rejected a good proportion of artifactual components extracted by ICA, while preserving almost all EEG components. The misclassification rate was comparable to the variability observed in human classification. Current ICA methods of artifact removal require a tedious visual classification of the components. The proposed system automates this process and removes simultaneously multiple types of artifacts.

  14. Sleep-Wake Evaluation from Whole-Night Non-Contact Audio Recordings of Breathing Sounds

    PubMed Central

    Dafna, Eliran; Tarasiuk, Ariel; Zigel, Yaniv

    2015-01-01

    Study Objectives To develop and validate a novel non-contact system for whole-night sleep evaluation using breathing sounds analysis (BSA). Design Whole-night breathing sounds (using ambient microphone) and polysomnography (PSG) were simultaneously collected at a sleep laboratory (mean recording time 7.1 hours). A set of acoustic features quantifying breathing pattern were developed to distinguish between sleep and wake epochs (30 sec segments). Epochs (n = 59,108 design study and n = 68,560 validation study) were classified using AdaBoost classifier and validated epoch-by-epoch for sensitivity, specificity, positive and negative predictive values, accuracy, and Cohen's kappa. Sleep quality parameters were calculated based on the sleep/wake classifications and compared with PSG for validity. Setting University affiliated sleep-wake disorder center and biomedical signal processing laboratory. Patients One hundred and fifty patients (age 54.0±14.8 years, BMI 31.6±5.5 kg/m2, m/f 97/53) referred for PSG were prospectively and consecutively recruited. The system was trained (design study) on 80 subjects; validation study was blindly performed on the additional 70 subjects. Measurements and Results Epoch-by-epoch accuracy rate for the validation study was 83.3% with sensitivity of 92.2% (sleep as sleep), specificity of 56.6% (awake as awake), and Cohen's kappa of 0.508. Comparing sleep quality parameters of BSA and PSG demonstrate average error of sleep latency, total sleep time, wake after sleep onset, and sleep efficiency of 16.6 min, 35.8 min, and 29.6 min, and 8%, respectively. Conclusions This study provides evidence that sleep-wake activity and sleep quality parameters can be reliably estimated solely using breathing sound analysis. This study highlights the potential of this innovative approach to measure sleep in research and clinical circumstances. PMID:25710495

  15. MOJAVE - XIV. Shapes and opening angles of AGN jets

    NASA Astrophysics Data System (ADS)

    Pushkarev, A. B.; Kovalev, Y. Y.; Lister, M. L.; Savolainen, T.

    2017-07-01

    We present 15 GHz stacked VLBA images of 373 jets associated with active galactic nuclei (AGNs) having at least five observing epochs within a 20 yr time interval 1994-2015 from the Monitoring Of Jets in Active galactic nuclei with VLBA Experiments (MOJAVE) programme and/or its precursor, the 2-cm VLBA Survey. These data are supplemented by 1.4 GHz single-epoch VLBA observations of 135 MOJAVE AGNs to probe larger scale jet structures. The typical jet geometry is found to be close to conical on scales from hundreds to thousands of parsecs, while a number of galaxies show quasi-parabolic streamlines on smaller scales. A true jet geometry in a considerable fraction of AGNs appears only after stacking epochs over several years. The jets with significant radial accelerated motion undergo more active collimation. We have analysed total intensity jet profiles transverse to the local jet ridgeline and derived both apparent and intrinsic opening angles of the flows, with medians of 21.5° and 1.3°, respectively. The Fermi LAT-detected gamma-ray AGNs in our sample have, on average, wider apparent and narrower intrinsic opening angle, and smaller viewing angle than non-LAT-detected AGNs. We have established a highly significant correlation between the apparent opening angle and gamma-ray luminosity, driven by Doppler beaming and projection effects.

  16. Geomagnetic activity during 10 - 11 solar cycles that has been observed by old Russian observatories.

    NASA Astrophysics Data System (ADS)

    Seredyn, Tomasz; Wysokinski, Arkadiusz; Kobylinski, Zbigniew; Bialy, Jerzy

    2016-07-01

    A good knowledge of solar-terrestrial relations during past solar activity cycles could give the appropriate tools for a correct space weather forecast. The paper focuses on the analysis of the historical collections of the ground based magnetic observations and their operational indices from the period of two sunspot solar cycles 10 - 11, period 1856 - 1878 (Bartels rotations 324 - 635). We use hourly observations of H and D geomagnetic field components registered at Russian stations: St. Petersburg - Pavlovsk, Barnaul, Ekaterinburg, Nertshinsk, Sitka, and compare them to the data obtained from the Helsinki observatory. We compare directly these records and also calculated from the data of the every above mentioned station IHV indices introduced by Svalgaard (2003), which have been used for further comparisons in epochs of assumed different polarity of the heliospheric magnetic field. We used also local index C9 derived by Zosimovich (1981) from St. Petersburg - Pavlovsk data. Solar activity is represented by sunspot numbers. The correlative and continuous wavelet analyses are applied for estimation of the correctness of records from different magnetic stations. We have specially regard to magnetic storms in the investigated period and the special Carrington event of 1-2 Sep 1859. Generally studied magnetic time series correctly show variability of the geomagnetic activity. Geomagnetic activity presents some delay in relation to solar one as it is seen especially during descending and minimum phase of the even 11-year cycle. This pattern looks similarly in the case of 16 - 17 solar cycles.

  17. Validation of Regression-Based Myogenic Correction Techniques for Scalp and Source-Localized EEG

    PubMed Central

    McMenamin, Brenton W.; Shackman, Alexander J.; Maxwell, Jeffrey S.; Greischar, Lawrence L.; Davidson, Richard J.

    2008-01-01

    EEG and EEG source-estimation are susceptible to electromyographic artifacts (EMG) generated by the cranial muscles. EMG can mask genuine effects or masquerade as a legitimate effect - even in low frequencies, such as alpha (8–13Hz). Although regression-based correction has been used previously, only cursory attempts at validation exist and the utility for source-localized data is unknown. To address this, EEG was recorded from 17 participants while neurogenic and myogenic activity were factorially varied. We assessed the sensitivity and specificity of four regression-based techniques: between-subjects, between-subjects using difference-scores, within-subjects condition-wise, and within-subject epoch-wise on the scalp and in data modeled using the LORETA algorithm. Although within-subject epoch-wise showed superior performance on the scalp, no technique succeeded in the source-space. Aside from validating the novel epoch-wise methods on the scalp, we highlight methods requiring further development. PMID:19298626

  18. Evolution of the luminosity function of extragalactic objects

    NASA Technical Reports Server (NTRS)

    Petrosian, V.

    1985-01-01

    A nonparametric procedure for determination of the evolution of the luminosity function of extragalactic objects and use of this for prediction of expected redshift and luminosity distribution of objects is described. The relation between this statistical evolution of the population and their physical evolution, such as the variation with cosmological epoch of their luminosity and formation rate is presented. This procedure when applied to a sample of optically selected quasars with redshifts less than two shows that the luminosity function evolves more strongly for higher luminosities, indicating a larger quasar activity at earlier epochs and a more rapid evolution of the objects during their higher luminosity phases. It is also shown that absence of many quasars at redshifts greater than three implies slowing down of this evolution in the conventional cosmological models, perhaps indicating that this is near the epoch of the birth of the quasar (and galaxies).

  19. Improved survival and neurodevelopmental outcomes among extremely premature infants born near the limit of viability.

    PubMed

    Younge, Noelle; Smith, P Brian; Gustafson, Kathryn E; Malcolm, William; Ashley, Patricia; Cotten, C Michael; Goldberg, Ronald N; Goldstein, Ricki F

    2016-04-01

    Infants born near the limit of viability are at high risk for death or adverse neurodevelopmental outcomes. It is unclear whether these outcomes have improved over the past 15 years. To determine if death and neurodevelopmental impairment have declined over the past 15 years in infants born at 22 to 24 weeks' gestation. Retrospective cohort study. We identified infants born at 22 to 24 weeks' gestation in our center in two epochs: 1998-2004 (Epoch 1) and 2005-2011 (Epoch 2). The primary outcome, death or neurodevelopmental impairment, was evaluated at 17-25 months' corrected gestational age with neurologic exams and Bayley Scales of Infant Development. Perinatal characteristics, major morbidities, and outcomes were compared between epochs. Birth weight and gestational age were similar between 170 infants in Epoch 1 and 187 infants in Epoch 2. Mortality was significantly lower in Epoch 2, 55% vs. 42% (p=0.02). Among surviving infants, late-onset sepsis (p<0.01), bronchopulmonary dysplasia (p<0.01), and surgical necrotizing enterocolitis (p=0.04) were less common in Epoch 2. Neurodevelopmental impairment among surviving infants declined from 68% in Epoch 1 to 47% in Epoch 2, p=0.02. Odds of death or NDI were significantly lower in Epoch 2 vs. Epoch 1, OR=0.31 (95% confidence interval; 0.16, 0.58). Risk of death or neurodevelopmental impairment decreased over time in infants born at 22 to 24 weeks' gestation. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  20. Cassini Observes the Active South Pole of Enceladus

    NASA Technical Reports Server (NTRS)

    Porco, C. C.; Helfenstein P.; Thomas, P. C.; Ingersoll, A. P.; Wisdom, J.; West, R.; Neukum, G.; Denk, T.; Wagner, R.; Roatsch, T.; hide

    2007-01-01

    Cassini has identified a geologically active province a the south pole of Saturn's moon Enceladus. The shape of Enceladus suggests a possible intense heating epoch in the past by capture into a 1:4 secondary spin/orbit resonance.

  1. Diagnostic Thresholds for Quantitative REM Sleep Phasic Burst Duration, Phasic and Tonic Muscle Activity, and REM Atonia Index in REM Sleep Behavior Disorder with and without Comorbid Obstructive Sleep Apnea

    PubMed Central

    McCarter, Stuart J.; St. Louis, Erik K.; Duwell, Ethan J.; Timm, Paul C.; Sandness, David J.; Boeve, Bradley F.; Silber, Michael H.

    2014-01-01

    Objectives: We aimed to determine whether phasic burst duration and conventional REM sleep without atonia (RSWA) methods could accurately diagnose REM sleep behavior disorder (RBD) patients with comorbid OSA. Design: We visually analyzed RSWA phasic burst durations, phasic, “any,” and tonic muscle activity by 3-s mini-epochs, phasic activity by 30-s (AASM rules) epochs, and conducted automated REM atonia index (RAI) analysis. Group RSWA metrics were analyzed and regression models fit, with receiver operating characteristic (ROC) curves determining the best diagnostic cutoff thresholds for RBD. Both split-night and full-night polysomnographic studies were analyzed. Setting: N/A. Participants: Parkinson disease (PD)-RBD (n = 20) and matched controls with (n = 20) and without (n = 20) OSA. Interventions: N/A. Measurements and Results: All mean RSWA phasic burst durations and muscle activities were higher in PD-RBD patients than controls (P < 0.0001), and RSWA associations with PD-RBD remained significant when adjusting for age, gender, and REM AHI (P < 0.0001). RSWA muscle activity (phasic, “any”) cutoffs for 3-s mini-epoch scorings were submentalis (SM) (15.5%, 21.6%), anterior tibialis (AT) (30.2%, 30.2%), and combined SM/AT (37.9%, 43.4%). Diagnostic cutoffs for 30-s epochs (AASM criteria) were SM 2.8%, AT 11.3%, and combined SM/AT 34.7%. Tonic muscle activity cutoff of 1.2% was 100% sensitive and specific, while RAI (SM) cutoff was 0.88. Phasic muscle burst duration cutoffs were: SM (0.65) and AT (0.79) seconds. Combining phasic burst durations with RSWA muscle activity improved sensitivity and specificity of RBD diagnosis. Conclusions: This study provides evidence for REM sleep without atonia diagnostic thresholds applicable in Parkinson disease-REM sleep behavior disorder (PD-RBD) patient populations with comorbid OSA that may be useful toward distinguishing PD-RBD in typical outpatient populations. Citation: McCarter SJ, St. Louis EK, Duwell EJ, Timm PC, Sandness DJ, Boeve BF, Silber MH. Diagnostic thresholds for quantitative REM sleep phasic burst duration, phasic and tonic muscle activity, and REM atonia index in REM sleep behavior disorder with and without comorbid obstructive sleep apnea. SLEEP 2014;37(10):1649-1662. PMID:25197816

  2. Suzaku Observes Weak Flares from IGRJ17391-3021 Representing a Common Low-Activity State in this SFXT

    NASA Technical Reports Server (NTRS)

    Bodaghee, A.; Tomsick, J. A.; Rodriquez, J.; Chaty, S.; Pottschmidt, K.; Walter, R.; Romano, P.

    2010-01-01

    We present an analysis of a 37-ks observation of the supergiant fast X-ray transient (SFXT) IGRJ17391 -3021 (=XTEJ1739-302) gathered with Suzaku. The source evolved from quiescence to a low-activity level culminating in three weak flares lasting approx.3 ks each in which the peak luminosity is only a factor of 5 times that of the pre-flare luminosity. The minimum observed luminosity was 1.3 x 10(exp 33) erg/s (d/2.7 kpc)(exp 2) in the 0.5-10 keV range. The weak flares are accompanied by significant changes in the spectral parameters including a column density (N(sub H) = (4.1(+0.4/-0.5)) x 10(exp 22)/sq cm) that is approx.2-9 times the absorption measured during quiescence. Accretion of obscuring clumps of stellar wind material can explain both the small flares and the increase in NH. Placing this observation in the context of the recent Swift monitoring campaign, we find that weak-flaring episodes, or at least epochs of enhanced activity just above the quiescent level but well below the moderately bright or high-luminosity outbursts, represent more than 60+/-5% of all observations in the 0.5-10keV energy range making this the most common state in the emission behavior of IGRJ17391 -3021.

  3. The VLA Sky Survey (VLASS): Overview and First Results

    NASA Astrophysics Data System (ADS)

    Myers, Steven T.; VLASS Survey Team, Survey Science Group (SSG)

    2018-01-01

    The VLA Sky Survey (VLASS) is a 5520 hour spectropolarimetric synoptic survey covering the 33885 square degrees of the sky above Declination -40 degrees from 2-4 GHz at 2.5" angular resolution using the upgraded Karl G. Jansky Very Large Array (VLA). Over the survey duration of 7 years, each area of the sky will be covered in 3 epochs spaced 32 months apart, to a projected depth of 0.12mJy/beam rms noise per epoch and 0.07mJy/beam for 3 epochs combined. The VLASS employs on-the-fly mosaicking (OTFM) to rapidly scan the sky with a net speed of approximately 20 sq. degrees per hour. The high-level science goals for the survey include the identification and precise location of radio transients, the measurement of magnetic fields in our galaxy and beyond, and the study of radio emission from galaxies and active galactic nuclei throughout the Universe. The ability of the VLASS to see through dust allows us to unveil phenomena such as hidden cosmic explosions, emission from deep within our galaxy, and supermassive black holes buried within host galaxies.The VLASS was proposed in 2014 by our community-led Survey Science Group (SSG). VLASS Pilot observations were taken in mid-2016, and the first epoch covering half the area (VLASS1.1) commenced in September 2017. The raw data from the VLASS are available in the NRAO archive immediately with no proprietary period. The Basic Data Products (BDP) that will be produced by the survey team are public and will additionally include: calibrated visibility data, quick-look continuum images (with a goal of posting to the archive within 1 week of observation), single-epoch and cumulative combined-epoch images, spectral image cubes, and basic object catalogs. Single-epoch and cumulative images are in intensity and linear polarization (Stokes IQU). In addition to the BDP provided by NRAO and served through the NRAO archive, there are plans for Enhanced Data Products and Services to be provided by the community in partnership with the VLASS team.In this presentation we describe the science goals, survey design, and technical implementation for the VLASS, and highlight results from the Pilot and the first epoch observations taken so far.

  4. Using the Inflection Points and Rates of Growth and Decay to Predict Levels of Solar Activity

    NASA Technical Reports Server (NTRS)

    Wilson, Robert M.; Hathaway, David H.

    2008-01-01

    The ascending and descending inflection points and rates of growth and decay at specific times during the sunspot cycle are examined as predictors for future activity. On average, the ascending inflection point occurs about 1-2 yr after sunspot minimum amplitude (Rm) and the descending inflection point occurs about 6-7 yr after Rm. The ascending inflection point and the inferred slope (including the 12-mo moving average (12-mma) of (Delta)R (the month-to-month change in the smoothed monthly mean sunspot number (R)) at the ascending inflection point provide strong indications as to the expected size of the ongoing cycle s sunspot maximum amplitude (RM), while the descending inflection point appears to provide an indication as to the expected length of the ongoing cycle. The value of the 12-mma of (Delta)R at elapsed time T = 27 mo past the epoch of RM (E(RM)) seems to provide a strong indication as to the expected size of Rm for the following cycle. The expected Rm for cycle 24 is 7.6 +/- 4.4 (the 90-percent prediction interval), occurring before September 2008. Evidence is also presented for secular rises in selected cycle-related parameters and for preferential grouping of sunspot cycles by amplitude and/or period.

  5. VARIATIONS OF THE 10 mum SILICATE FEATURES IN THE ACTIVELY ACCRETING T TAURI STARS: DG Tau AND XZ Tau

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bary, Jeffrey S.; Leisenring, Jarron M.; Skrutskie, Michael F., E-mail: jbary@colgate.ed, E-mail: jml2u@virginia.ed, E-mail: mfs4n@virginia.ed

    2009-11-20

    Using the Infrared Spectrograph aboard the Spitzer Space Telescope, we observed multiple epochs of 11 actively accreting T Tauri stars in the nearby Taurus-Auriga star-forming region. In total, 88 low-resolution mid-infrared spectra were collected over 1.5 years in Cycles 2 and 3. The results of this multi-epoch survey show that the 10 mum silicate complex in the spectra of two sources-DG Tau and XZ Tau-undergoes significant variations with the silicate feature growing both weaker and stronger over month- and year-long timescales. Shorter timescale variations on day- to week-long timescales were not detected within the measured flux errors. The time resolutionmore » coverage of this data set is inadequate for determining if the variations are periodic. Pure emission compositional models of the silicate complex in each epoch of the DG Tau and XZ Tau spectra provide poor fits to the observed silicate features. These results agree with those of previous groups that attempted to fit only single-epoch observations of these sources. Simple two-temperature, two-slab models with similar compositions successfully reproduce the observed variations in the silicate features. These models hint at a self-absorption origin of the diminution of the silicate complex instead of a compositional change in the population of emitting dust grains. We discuss several scenarios for producing such variability including disk shadowing, vertical mixing, variations in disk heating, and disk wind events associated with accretion outbursts.« less

  6. A New Binary Star System of EW Type in Draco: GSC 03905-01870

    NASA Astrophysics Data System (ADS)

    Barquin, S.

    2018-05-01

    Discovery of a new binary star system (GSC 03905-01870 = USNO-B1.0 1431-0327922 = UCAC4 716-059522) in the Draco constellation is presented. It was discovered during a search for previously unreported eclipsing binary stars through the ASAS-SN database. The shape of the light curve and its characteristics (period of 0.428988+-0.000001 d, amplitude of 0.34+-0.02 V Mag, primary minimum epoch HJD 2457994.2756+-0.0002) indicates that the new variable star is an eclipsing binary of W Ursae Majoris type. I registered this variable star in The International Variable Star Index (VSX), its AAVSO UID is 000-BMP-891.

  7. Superorbital Period in the high mass X-ray binary 2S 0114+650

    NASA Astrophysics Data System (ADS)

    Farrell, S.; Sood, R.; O'Neill, P.

    2004-05-01

    We report the identification of a superorbital period in the high mass X-ray binary 2S 0114+650. RXTE ASM observations of this object from 1996 Jan 5 to 2003 May 26 show the presence of a modulation at a period of 30.7 +/- 0.2 days. This period is detected using a Lomb-Scargle periodogram, and has a false-alarm probability of 5E-12. Epoch folding of the data gives an ephemeris of JD 2450079.4 (+/- 0.7) +30.7 (+/- 0.2)N, where N is the cycle number, with phase zero defined as the modulation minimum, and a full amplitude of 60 +/- 20%.

  8. Performance characteristics of a batch service queueing system with functioning server failure and multiple vacations

    NASA Astrophysics Data System (ADS)

    Niranjan, S. P.; Chandrasekaran, V. M.; Indhira, K.

    2018-04-01

    This paper examines bulk arrival and batch service queueing system with functioning server failure and multiple vacations. Customers are arriving into the system in bulk according to Poisson process with rate λ. Arriving customers are served in batches with minimum of ‘a’ and maximum of ‘b’ number of customers according to general bulk service rule. In the service completion epoch if the queue length is less than ‘a’ then the server leaves for vacation (secondary job) of random length. After a vacation completion, if the queue length is still less than ‘a’ then the server leaves for another vacation. The server keeps on going vacation until the queue length reaches the value ‘a’. The server is not stable at all the times. Sometimes it may fails during functioning of customers. Though the server fails service process will not be interrupted.It will be continued for the current batch of customers with lower service rate than the regular service rate. The server will be repaired after the service completion with lower service rate. The probability generating function of the queue size at an arbitrary time epoch will be obtained for the modelled queueing system by using supplementary variable technique. Moreover various performance characteristics will also be derived with suitable numerical illustrations.

  9. Administering an epoch initiated for remote memory access

    DOEpatents

    Blocksome, Michael A; Miller, Douglas R

    2014-03-18

    Methods, systems, and products are disclosed for administering an epoch initiated for remote memory access that include: initiating, by an origin application messaging module on an origin compute node, one or more data transfers to a target compute node for the epoch; initiating, by the origin application messaging module after initiating the data transfers, a closing stage for the epoch, including rejecting any new data transfers after initiating the closing stage for the epoch; determining, by the origin application messaging module, whether the data transfers have completed; and closing, by the origin application messaging module, the epoch if the data transfers have completed.

  10. Administering an epoch initiated for remote memory access

    DOEpatents

    Blocksome, Michael A; Miller, Douglas R

    2012-10-23

    Methods, systems, and products are disclosed for administering an epoch initiated for remote memory access that include: initiating, by an origin application messaging module on an origin compute node, one or more data transfers to a target compute node for the epoch; initiating, by the origin application messaging module after initiating the data transfers, a closing stage for the epoch, including rejecting any new data transfers after initiating the closing stage for the epoch; determining, by the origin application messaging module, whether the data transfers have completed; and closing, by the origin application messaging module, the epoch if the data transfers have completed.

  11. Administering an epoch initiated for remote memory access

    DOEpatents

    Blocksome, Michael A.; Miller, Douglas R.

    2013-01-01

    Methods, systems, and products are disclosed for administering an epoch initiated for remote memory access that include: initiating, by an origin application messaging module on an origin compute node, one or more data transfers to a target compute node for the epoch; initiating, by the origin application messaging module after initiating the data transfers, a closing stage for the epoch, including rejecting any new data transfers after initiating the closing stage for the epoch; determining, by the origin application messaging module, whether the data transfers have completed; and closing, by the origin application messaging module, the epoch if the data transfers have completed.

  12. Disturbance zonal and vertical plasma drifts in the Peruvian sector during solar minimum phases

    NASA Astrophysics Data System (ADS)

    Santos, A. M.; Abdu, M. A.; Souza, J. R.; Sobral, J. H. A.; Batista, I. S.

    2016-03-01

    In the present work, we investigate the behavior of the equatorial F region zonal plasma drifts over the Peruvian region under magnetically disturbed conditions during two solar minimum epochs, one of them being the recent prolonged solar activity minimum. The study utilizes the vertical and zonal components of the plasma drifts measured by the Jicamarca (11.95°S; 76.87°W) incoherent scatter radar during two events that occurred on 10 April 1997 and 24 June 2008 and model calculation of the zonal drift in a realistic ionosphere simulated by the Sheffield University Plasmasphere-Ionosphere Model-INPE. Two main points are focused: (1) the connection between electric fields and plasma drifts under prompt penetration electric field during a disturbed periods and (2) anomalous behavior of daytime zonal drift in the absence of any magnetic storm. A perfect anticorrelation between vertical and zonal drifts was observed during the night and in the initial and growth phases of the magnetic storm. For the first time, based on a realistic low-latitude ionosphere, we will show, on a detailed quantitative basis, that this anticorrelation is driven mainly by a vertical Hall electric field induced by the primary zonal electric field in the presence of an enhanced nighttime E region ionization. It is shown that an increase in the field line-integrated Hall-to-Pedersen conductivity ratio (∑H/∑P), which can arise from precipitation of energetic particles in the region of the South American Magnetic Anomaly, is capable of explaining the observed anticorrelation between the vertical and zonal plasma drifts. Evidence for the particle ionization is provided from the occurrence of anomalous sporadic E layers over the low-latitude station, Cachoeira Paulista (22.67°S; 44.9°W)—Brazil. It will also be shown that the zonal plasma drift reversal to eastward in the afternoon two hours earlier than its reference quiet time pattern is possibly caused by weakening of the zonal wind system during the prolonged solar minimum period.

  13. Short Communication - Urease inhibitory activity of Hippophae rhamnoids and Cassia fistula.

    PubMed

    Khan, Barkat Ali; Akhtar, Naveed; Khan, Haroon; Mustafa, Ghulam; Niazi, Zahid Rasul; Menaa, Farid

    2017-09-01

    The rational use of plants as medicine is traced back over five epochs to ancient documents of early civilizations and is certainly as old as mankind. These medicines originally developed from crude drugs like tinctures and tinctures. Minimum 119 chemical substances are derived from 90 plant species and used all over the world as medicines, several of them containing compounds derived from or modelled after naturally occurring lead molecules and 74% of these derived from orthodox medicinal plants. 252 drugs (11%) are believed to be basic and essential by the WHO and are exclusively of plant origin. We have examined anti-urease activity of ethyl alcohol (Et-OH) and methyl alcohol (Me-OH) extracts of H. rhamnoides and Cassia fistula. Berthelot assay was used for the determination of anti-urease activity. The enzyme activity and inhibition was measured through catalytic effects of urease on urea by measuring change in absorbance in the absence and in the presence of inhibitor at 625nm using UV spectrophotometer. In the study, both Et-OH and Me-OH extracts of H. rhamnoides (91.69%±1.21) and C. fisstula (79.44%±0.55) showed stronger action against urease activity. An overview on the medicinal uses of H. rhamnoides and C. fisstula showing anti-urease activity may predict their possible alternative use for stomach problems. This study may help to explain the beneficial effects of these plants against stomach infection associated with pathogenic strains of H. pylori as Urease is the most prominent protein component of H. pylori.

  14. Are muscle activation patterns altered during shod and barefoot running with a forefoot footfall pattern?

    PubMed

    Ervilha, Ulysses Fernandes; Mochizuki, Luis; Figueira, Aylton; Hamill, Joseph

    2017-09-01

    This study aimed to investigate the activation of lower limb muscles during barefoot and shod running with forefoot or rearfoot footfall patterns. Nine habitually shod runners were asked to run straight for 20 m at self-selected speed. Ground reaction forces and thigh and shank muscle surface electromyographic (EMG) were recorded. EMG outcomes (EMG intensity [iEMG], latency between muscle activation and ground reaction force, latency between muscle pairs and co-activation index between muscle pairs) were compared across condition (shod and barefoot), running cycle epochs (pre-strike, strike, propulsion) and footfall (rearfoot and forefoot) by ANOVA. Condition affected iEMG at pre-strike epoch. Forefoot and rearfoot strike patterns induced different EMG activation time patterns affecting co-activation index for pairs of thigh and shank muscles. All these timing changes suggest that wearing shoes or not is less important for muscle activation than the way runners strike the foot on the ground. In conclusion, the guidance for changing external forces applied on lower limbs should be pointed to the question of rearfoot or forefoot footfall patterns.

  15. Sleepwalking episodes are preceded by arousal-related activation in the cingulate motor area: EEG current density imaging.

    PubMed

    Januszko, Piotr; Niemcewicz, Szymon; Gajda, Tomasz; Wołyńczyk-Gmaj, Dorota; Piotrowska, Anna Justyna; Gmaj, Bartłomiej; Piotrowski, Tadeusz; Szelenberger, Waldemar

    2016-01-01

    To investigate local arousal fluctuations in adults who received ICSD-2 diagnosis of somnambulism. EEG neuroimaging (eLORETA) was utilized to compare current density distribution for 4s epochs immediately preceding sleepwalking episode (from -4.0 s to 0 s) to the distribution during earlier 4s epochs (from -8.0 s to -4.0 s) in 20 EEG segments from 15 patients. Comparisons between eLORETA images revealed significant (t>4.52; p<0.05) brain activations before onset of sleepwalking, with greater current density within beta 3 frequency range (24-30 Hz) in Brodmann areas 33 and 24. Sleepwalking motor events are associated with arousal-related activation of cingulate motor area. These results support the notion of blurred boundaries between wakefulness and NREM sleep in sleepwalking. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  16. Interdecadal change in the Eurasia-Pacific anti-phase relation of atmospheric mass and its possible link with PDO

    NASA Astrophysics Data System (ADS)

    Zhang, Qian; Guan, Zhaoyong

    2017-02-01

    Based on the known climatic shift that occurred in 1976, we divide the present study period into two epochs: epoch-I, for 1958-1976; and epoch-II, for 1977-2002. Using ERA-40 and the 20th century reanalysis data, we investigate the interdecadal change in the Eurasia-Pacific anti-phase relation (EPAR) pattern of atmospheric mass (AM) during boreal winter before and after 1976. It is found that anomalous AM over lands is highly and negatively correlated with anomalous AM over oceans in the Northern Hemisphere during the winter season. This correlation does not change much from epoch-I to epoch-II. However, the correlation pattern of surface air pressure anomalies with variations of anomalous AM over lands changes remarkably from epoch-I to epoch-II; the EPAR pattern emerges evidently in the later period, whereas it is not significant in epoch-I. The occurrence of the EPAR pattern in epoch-II may be attributable to the Pacific Decadal Oscillation (PDO). The PDO may modulate the EPAR pattern in two ways. Firstly, the interdecadal component of the PDO as a background may modulate the intensities of the Aleutian low, East Asian trough, and westerly flow, acting as a waveguide during the warm phase (epoch-II) of the PDO. Secondly, the interannual variations of sea surface temperature anomalies in the North Pacific, in association with the PDO, may affect the interannual variations of AM, which facilitates the existence of the EPAR pattern in epoch-II only. With the teleconnection pattern having changed before and after 1976, winter climate anomalies, including rainfall and temperature, are found to be different in many regions in the Northern Hemisphere between epoch-I and epoch-II. All the results of the present work are meaningful for a better understanding of climate anomalies during boreal winter.

  17. Binaural Beat: A Failure to Enhance EEG Power and Emotional Arousal

    PubMed Central

    López-Caballero, Fran; Escera, Carles

    2017-01-01

    When two pure tones of slightly different frequencies are delivered simultaneously to the two ears, is generated a beat whose frequency corresponds to the frequency difference between them. That beat is known as acoustic beat. If these two tones are presented one to each ear, they still produce the sensation of the same beat, although no physical combination of the tones occurs outside the auditory system. This phenomenon is called binaural beat. In the present study, we explored the potential contribution of binaural beats to the enhancement of specific electroencephalographic (EEG) bands, as previous studies suggest the potential usefulness of binaural beats as a brainwave entrainment tool. Additionally, we analyzed the effects of binaural-beat stimulation on two psychophysiological measures related to emotional arousal: heart rate and skin conductance. Beats of five different frequencies (4.53 Hz -theta-, 8.97 Hz -alpha-, 17.93 Hz -beta-, 34.49 Hz -gamma- or 57.3 Hz -upper-gamma) were presented binaurally and acoustically for epochs of 3 min (Beat epochs), preceded and followed by pink noise epochs of 90 s (Baseline and Post epochs, respectively). In each of these epochs, we analyzed the EEG spectral power, as well as calculated the heart rate and skin conductance response (SCR). For all the beat frequencies used for stimulation, no significant changes between Baseline and Beat epochs were observed within the corresponding EEG bands, neither with binaural or with acoustic beats. Additional analysis of spectral EEG topographies yielded negative results for the effect of binaural beats in the scalp distribution of EEG spectral power. In the psychophysiological measures, no changes in heart rate and skin conductance were observed for any of the beat frequencies presented. Our results do not support binaural-beat stimulation as a potential tool for the enhancement of EEG oscillatory activity, nor to induce changes in emotional arousal. PMID:29187819

  18. Binaural Beat: A Failure to Enhance EEG Power and Emotional Arousal.

    PubMed

    López-Caballero, Fran; Escera, Carles

    2017-01-01

    When two pure tones of slightly different frequencies are delivered simultaneously to the two ears, is generated a beat whose frequency corresponds to the frequency difference between them. That beat is known as acoustic beat. If these two tones are presented one to each ear, they still produce the sensation of the same beat, although no physical combination of the tones occurs outside the auditory system. This phenomenon is called binaural beat. In the present study, we explored the potential contribution of binaural beats to the enhancement of specific electroencephalographic (EEG) bands, as previous studies suggest the potential usefulness of binaural beats as a brainwave entrainment tool. Additionally, we analyzed the effects of binaural-beat stimulation on two psychophysiological measures related to emotional arousal: heart rate and skin conductance. Beats of five different frequencies (4.53 Hz -theta-, 8.97 Hz -alpha-, 17.93 Hz -beta-, 34.49 Hz -gamma- or 57.3 Hz -upper-gamma) were presented binaurally and acoustically for epochs of 3 min (Beat epochs), preceded and followed by pink noise epochs of 90 s (Baseline and Post epochs, respectively). In each of these epochs, we analyzed the EEG spectral power, as well as calculated the heart rate and skin conductance response (SCR). For all the beat frequencies used for stimulation, no significant changes between Baseline and Beat epochs were observed within the corresponding EEG bands, neither with binaural or with acoustic beats. Additional analysis of spectral EEG topographies yielded negative results for the effect of binaural beats in the scalp distribution of EEG spectral power. In the psychophysiological measures, no changes in heart rate and skin conductance were observed for any of the beat frequencies presented. Our results do not support binaural-beat stimulation as a potential tool for the enhancement of EEG oscillatory activity, nor to induce changes in emotional arousal.

  19. Global trends in the awareness of sepsis: insights from search engine data between 2012 and 2017.

    PubMed

    Jabaley, Craig S; Blum, James M; Groff, Robert F; O'Reilly-Shah, Vikas N

    2018-01-17

    Sepsis is an established global health priority with high mortality that can be curtailed through early recognition and intervention; as such, efforts to raise awareness are potentially impactful and increasingly common. We sought to characterize trends in the awareness of sepsis by examining temporal, geographic, and other changes in search engine utilization for sepsis information-seeking online. Using time series analyses and mixed descriptive methods, we retrospectively analyzed publicly available global usage data reported by Google Trends (Google, Palo Alto, CA, USA) concerning web searches for the topic of sepsis between 24 June 2012 and 24 June 2017. Google Trends reports aggregated and de-identified usage data for its search products, including interest over time, interest by region, and details concerning the popularity of related queries where applicable. Outlying epochs of search activity were identified using autoregressive integrated moving average modeling with transfer functions. We then identified awareness campaigns and news media coverage that correlated with epochs of significantly heightened search activity. A second-order autoregressive model with transfer functions was specified following preliminary outlier analysis. Nineteen significant outlying epochs above the modeled baseline were identified in the final analysis that correlated with 14 awareness and news media events. Our model demonstrated that the baseline level of search activity increased in a nonlinear fashion. A recurrent cyclic increase in search volume beginning in 2012 was observed that correlates with World Sepsis Day. Numerous other awareness and media events were correlated with outlying epochs. The average worldwide search volume for sepsis was less than that of influenza, myocardial infarction, and stroke. Analyzing aggregate search engine utilization data has promise as a mechanism to measure the impact of awareness efforts. Heightened information-seeking about sepsis occurs in close proximity to awareness events and relevant news media coverage. Future work should focus on validating this approach in other contexts and comparing its results to traditional methods of awareness campaign evaluation.

  20. Group Analysis in MNE-Python of Evoked Responses from a Tactile Stimulation Paradigm: A Pipeline for Reproducibility at Every Step of Processing, Going from Individual Sensor Space Representations to an across-Group Source Space Representation

    PubMed Central

    Andersen, Lau M.

    2018-01-01

    An important aim of an analysis pipeline for magnetoencephalographic data is that it allows for the researcher spending maximal effort on making the statistical comparisons that will answer the questions of the researcher, while in turn spending minimal effort on the intricacies and machinery of the pipeline. I here present a set of functions and scripts that allow for setting up a clear, reproducible structure for separating raw and processed data into folders and files such that minimal effort can be spend on: (1) double-checking that the right input goes into the right functions; (2) making sure that output and intermediate steps can be accessed meaningfully; (3) applying operations efficiently across groups of subjects; (4) re-processing data if changes to any intermediate step are desirable. Applying the scripts requires only general knowledge about the Python language. The data analyses are neural responses to tactile stimulations of the right index finger in a group of 20 healthy participants acquired from an Elekta Neuromag System. Two analyses are presented: going from individual sensor space representations to, respectively, an across-group sensor space representation and an across-group source space representation. The processing steps covered for the first analysis are filtering the raw data, finding events of interest in the data, epoching data, finding and removing independent components related to eye blinks and heart beats, calculating participants' individual evoked responses by averaging over epoched data and calculating a grand average sensor space representation over participants. The second analysis starts from the participants' individual evoked responses and covers: estimating noise covariance, creating a forward model, creating an inverse operator, estimating distributed source activity on the cortical surface using a minimum norm procedure, morphing those estimates onto a common cortical template and calculating the patterns of activity that are statistically different from baseline. To estimate source activity, processing of the anatomy of subjects based on magnetic resonance imaging is necessary. The necessary steps are covered here: importing magnetic resonance images, segmenting the brain, estimating boundaries between different tissue layers, making fine-resolution scalp surfaces for facilitating co-registration, creating source spaces and creating volume conductors for each subject. PMID:29403349

  1. Group Analysis in MNE-Python of Evoked Responses from a Tactile Stimulation Paradigm: A Pipeline for Reproducibility at Every Step of Processing, Going from Individual Sensor Space Representations to an across-Group Source Space Representation.

    PubMed

    Andersen, Lau M

    2018-01-01

    An important aim of an analysis pipeline for magnetoencephalographic data is that it allows for the researcher spending maximal effort on making the statistical comparisons that will answer the questions of the researcher, while in turn spending minimal effort on the intricacies and machinery of the pipeline. I here present a set of functions and scripts that allow for setting up a clear, reproducible structure for separating raw and processed data into folders and files such that minimal effort can be spend on: (1) double-checking that the right input goes into the right functions; (2) making sure that output and intermediate steps can be accessed meaningfully; (3) applying operations efficiently across groups of subjects; (4) re-processing data if changes to any intermediate step are desirable. Applying the scripts requires only general knowledge about the Python language. The data analyses are neural responses to tactile stimulations of the right index finger in a group of 20 healthy participants acquired from an Elekta Neuromag System. Two analyses are presented: going from individual sensor space representations to, respectively, an across-group sensor space representation and an across-group source space representation. The processing steps covered for the first analysis are filtering the raw data, finding events of interest in the data, epoching data, finding and removing independent components related to eye blinks and heart beats, calculating participants' individual evoked responses by averaging over epoched data and calculating a grand average sensor space representation over participants. The second analysis starts from the participants' individual evoked responses and covers: estimating noise covariance, creating a forward model, creating an inverse operator, estimating distributed source activity on the cortical surface using a minimum norm procedure, morphing those estimates onto a common cortical template and calculating the patterns of activity that are statistically different from baseline. To estimate source activity, processing of the anatomy of subjects based on magnetic resonance imaging is necessary. The necessary steps are covered here: importing magnetic resonance images, segmenting the brain, estimating boundaries between different tissue layers, making fine-resolution scalp surfaces for facilitating co-registration, creating source spaces and creating volume conductors for each subject.

  2. The sensory timecourses associated with conscious visual item memory and source memory.

    PubMed

    Thakral, Preston P; Slotnick, Scott D

    2015-09-01

    Previous event-related potential (ERP) findings have suggested that during visual item and source memory, nonconscious and conscious sensory (occipital-temporal) activity onsets may be restricted to early (0-800 ms) and late (800-1600 ms) temporal epochs, respectively. In an ERP experiment, we tested this hypothesis by separately assessing whether the onset of conscious sensory activity was restricted to the late epoch during source (location) memory and item (shape) memory. We found that conscious sensory activity had a late (>800 ms) onset during source memory and an early (<200 ms) onset during item memory. In a follow-up fMRI experiment, conscious sensory activity was localized to BA17, BA18, and BA19. Of primary importance, the distinct source memory and item memory ERP onsets contradict the hypothesis that there is a fixed temporal boundary separating nonconscious and conscious processing during all forms of visual conscious retrieval. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. PERIOD–COLOR AND AMPLITUDE–COLOR RELATIONS AT MAXIMUM AND MINIMUM LIGHT FOR RR LYRAE STARS IN THE SDSS STRIPE 82 REGION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ngeow, Chow-Choong; Kanbur, Shashi M.; Schrecengost, Zachariah

    Investigation of period–color (PC) and amplitude–color (AC) relations at the maximum and minimum light can be used to probe the interaction of the hydrogen ionization front (HIF) with the photosphere and the radiation hydrodynamics of the outer envelopes of Cepheids and RR Lyraes. For example, theoretical calculations indicated that such interactions would occur at minimum light for RR Lyrae and result in a flatter PC relation. In the past, the PC and AC relations have been investigated by using either the ( V − R ){sub MACHO} or ( V − I ) colors. In this work, we extend previousmore » work to other bands by analyzing the RR Lyraes in the Sloan Digital Sky Survey Stripe 82 Region. Multi-epoch data are available for RR Lyraes located within the footprint of the Stripe 82 Region in five ( ugriz ) bands. We present the PC and AC relations at maximum and minimum light in four colors: ( u − g ){sub 0}, ( g − r ){sub 0}, ( r − i ){sub 0}, and ( i − z ){sub 0}, after they are corrected for extinction. We found that the PC and AC relations for this sample of RR Lyraes show a complex nature in the form of flat, linear or quadratic relations. Furthermore, the PC relations at minimum light for fundamental mode RR Lyrae stars are separated according to the Oosterhoff type, especially in the ( g − r ){sub 0} and ( r − i ){sub 0} colors. If only considering the results from linear regressions, our results are quantitatively consistent with the theory of HIF-photosphere interaction for both fundamental and first overtone RR Lyraes.« less

  4. Global Peak in Atmospheric Radiocarbon Provides a Potential Definition for the Onset of the Anthropocene Epoch in 1965.

    PubMed

    Turney, Chris S M; Palmer, Jonathan; Maslin, Mark A; Hogg, Alan; Fogwill, Christopher J; Southon, John; Fenwick, Pavla; Helle, Gerhard; Wilmshurst, Janet M; McGlone, Matt; Bronk Ramsey, Christopher; Thomas, Zoë; Lipson, Mathew; Beaven, Brent; Jones, Richard T; Andrews, Oliver; Hua, Quan

    2018-02-19

    Anthropogenic activity is now recognised as having profoundly and permanently altered the Earth system, suggesting we have entered a human-dominated geological epoch, the 'Anthropocene'. To formally define the onset of the Anthropocene, a synchronous global signature within geological-forming materials is required. Here we report a series of precisely-dated tree-ring records from Campbell Island (Southern Ocean) that capture peak atmospheric radiocarbon ( 14 C) resulting from Northern Hemisphere-dominated thermonuclear bomb tests during the 1950s and 1960s. The only alien tree on the island, a Sitka spruce (Picea sitchensis), allows us to seasonally-resolve Southern Hemisphere atmospheric 14 C, demonstrating the 'bomb peak' in this remote and pristine location occurred in the last-quarter of 1965 (October-December), coincident with the broader changes associated with the post-World War II 'Great Acceleration' in industrial capacity and consumption. Our findings provide a precisely-resolved potential Global Stratotype Section and Point (GSSP) or 'golden spike', marking the onset of the Anthropocene Epoch.

  5. Photometry of symbiotic stars. XI. EG And, Z And, BF Cyg, CH Cyg, CI Cyg, V1329 Cyg, TX CVn, AG Dra, RW Hya, AR Pav, AG Peg, AX Per, QW Sge, IV Vir and the LMXB V934 Her

    NASA Astrophysics Data System (ADS)

    Skopal, A.; Pribulla, T.; Vaňko, M.; Velič, Z.; Semkov, E.; Wolf, M.; Jones, A.

    2004-02-01

    We present new photometric observations of EG And, Z And, BF Cyg, CH Cyg, CI Cyg, V1329 Cyg, TX CVn, AG Dra, RW Hya, AG Peg, AX Per, IV Vir and the peculiar M giant V934 Her, which were made in the standard Johnson UBV(R) system. QW Sge was measured in the Kron-Cousin B, V, RC, IC system and for AR Pav we present its new visual estimates. The current issue gathers observations of these objects to December 2003. The main results can be summarized as follows: EG And: The primary minimum in the U light curve (LC) occurred at the end of 2002. A 0.2 -- 0.3 mag brightening in U was detected in the autumn of 2003. Z And: At around August 2002 we detected for the first time a minimum, which is due to eclipse of the active object by the red giant. Measurements from 2003.3 are close to those of a quiescent phase. BF Cyg: In February 2003 a short-term flare developed in the LC. A difference in the depth of recent minima was detected. CH Cyg: This star was in a quiescent phase at a rather bright state. A shallow minimum occurred at ˜ JD 2 452 730, close to the position of the inferior conjunction of the giant in the inner binary of the triple-star model of CH Cyg. CI Cyg: Our observations cover the descending branch of a broad minimum. TX CVn: At/around the beginning of 2003 the star entered a bright stage containing a minimum at ˜ JD 2 452 660. AG Dra: New observations revealed two eruptions, which peaked in October 2002 and 2003 at ˜ 9.3 in U. AR Pav: Our new visual estimates showed a transient disappearance of a wave-like modulation in the star's brightness between the minima at epochs E = 66 and E = 68 and its reappearance. AG Peg: Our measurements from the end of 2001 showed rather complex profile of the LC. RW Hya: Observations follow behaviour of the wave-like variability of quiet symbiotics. AX Per: In May 2003 a 0.5 mag flare was detected following a rapid decrease of the light to a minimum. QW Sge: CCD observations in B, V, RC, IC bands cover a period from 1994.5 to 2003.5. An increase in the star's brightness by about 1 mag was observed in all passbands in 1997. Less pronounced brightening was detected in 1999/2000. V934 Her: Our observations did not show any larger variation in the optical as a reaction to its X-ray activity.

  6. Valence interacts with the early ERP old/new effect and arousal with the sustained ERP old/new effect for affective pictures.

    PubMed

    Van Strien, Jan W; Langeslag, Sandra J E; Strekalova, Nadja J; Gootjes, Liselotte; Franken, Ingmar H A

    2009-01-28

    To examine whether valence and arousal influence recognition memory during early automatic or during more sustained processes, event-related brain potentials (ERPs) of 21 women were recorded while they made old/new judgments in a continuous recognition task with pictures from the International Affective Picture System. The pictures were presented twice and differed in emotional valence and arousal. The P1 peak and four time windows were investigated: 200-300 ms, 300-400 ms, 400-600 ms, and 750-1000 ms after stimulus onset. There was a robust old/new effect starting in the 200-300 ms epoch and lasting all time windows. The valence effect was mainly present in the P1 peak and the 200-400 ms epoch, whereas the arousal effect was found in the 300-1000 ms epoch. Exploratory sLORETA analyses dissociated valence-dependent ventromedial prefrontal activity and arousal-dependent occipital activity in the 350-380 ms time window. Valence interacted with the 200-400 ms old/new effect at central and frontal sites. Arousal interacted with the 750-1000 ms old/new effect at posterior sites. It is concluded that valence influences fast recognition memory, while arousal may influence sustained encoding.

  7. Constraints on the power spectrum of the primordial density field from large-scale data - Microwave background and predictions of inflation

    NASA Technical Reports Server (NTRS)

    Kashlinsky, A.

    1992-01-01

    It is shown here that, by using galaxy catalog correlation data as input, measurements of microwave background radiation (MBR) anisotropies should soon be able to test two of the inflationary scenario's most basic predictions: (1) that the primordial density fluctuations produced were scale-invariant and (2) that the universe is flat. They should also be able to detect anisotropies of large-scale structure formed by gravitational evolution of density fluctuations present at the last scattering epoch. Computations of MBR anisotropies corresponding to the minimum of the large-scale variance of the MBR anisotropy are presented which favor an open universe with P(k) significantly different from the Harrison-Zeldovich spectrum predicted by most inflationary models.

  8. Earth Observing System Covariance Realism

    NASA Technical Reports Server (NTRS)

    Zaidi, Waqar H.; Hejduk, Matthew D.

    2016-01-01

    The purpose of covariance realism is to properly size a primary object's covariance in order to add validity to the calculation of the probability of collision. The covariance realism technique in this paper consists of three parts: collection/calculation of definitive state estimates through orbit determination, calculation of covariance realism test statistics at each covariance propagation point, and proper assessment of those test statistics. An empirical cumulative distribution function (ECDF) Goodness-of-Fit (GOF) method is employed to determine if a covariance is properly sized by comparing the empirical distribution of Mahalanobis distance calculations to the hypothesized parent 3-DoF chi-squared distribution. To realistically size a covariance for collision probability calculations, this study uses a state noise compensation algorithm that adds process noise to the definitive epoch covariance to account for uncertainty in the force model. Process noise is added until the GOF tests pass a group significance level threshold. The results of this study indicate that when outliers attributed to persistently high or extreme levels of solar activity are removed, the aforementioned covariance realism compensation method produces a tuned covariance with up to 80 to 90% of the covariance propagation timespan passing (against a 60% minimum passing threshold) the GOF tests-a quite satisfactory and useful result.

  9. Investigation of Sunspot Area Varying with Sunspot Number

    NASA Astrophysics Data System (ADS)

    Li, K. J.; Li, F. Y.; Zhang, J.; Feng, W.

    2016-11-01

    The statistical relationship between sunspot area (SA) and sunspot number (SN) is investigated through analysis of their daily observation records from May 1874 to April 2015. For a total of 1607 days, representing 3 % of the total interval considered, either SA or SN had a value of zero while the other parameter did not. These occurrences most likely reflect the report of short-lived spots by a single observatory and subsequent averaging of zero values over multiple stations. The main results obtained are as follows: i) The number of spotless days around the minimum of a solar cycle is statistically negatively correlated with the maximum strength of solar activity of that cycle. ii) The probability distribution of SA generally decreases monotonically with SA, but the distribution of SN generally increases first, then it decreases as a whole. The different probability distribution of SA and SN should strengthen their non-linear relation, and the correction factor [k] in the definition of SN may be one of the factors that cause the non-linearity. iii) The non-linear relation of SA and SN indeed exists statistically, and it is clearer during the maximum epoch of a solar cycle.

  10. Glacial geology of the Hellas region on Mars

    NASA Technical Reports Server (NTRS)

    Kargel, Jeffrey S.; Strom, Robert G.; Johnson, Natasha

    1991-01-01

    A glacial geologic interpretation was recently presented for Argyre, which is herein extended to Hellas. This glacial event is believed to constitute an important link in a global cryohydric epoch of Middle Amazonian age. At glacial maximum, ice apparently extended far beyond the regions of Argyre and Hellas, and formed what is termed as the Austral Ice Sheet, an agglomeration of several ice domes and lobes including the Hellas Lobe. It is concluded that Hellas was apparently heavily glaciated. Also glaciation was young by Martian standards (Middle Amazonian), and ancient by terrestrial standards. Glaciation appears to have occurred during the same period that other areas on Mars were experiencing glaciation and periglacial activity. Glaciation seems to have occurred as a geological brief epoch of intense geomorphic activity in an era characterized by long periods of relative inactivity.

  11. Restricted Ventilation Associated with Reduced Neurodevelopmental Impairment in Preterm Infants.

    PubMed

    Vliegenthart, Roseanne J S; Onland, Wes; van Wassenaer-Leemhuis, Aleid G; De Jaegere, Anne P M; Aarnoudse-Moens, Cornelieke S H; van Kaam, Anton H

    2017-01-01

    Restrictive use of invasive mechanical ventilation (IMV) in preterm infants reduces the risk of bronchopulmonary dysplasia (BPD). Our objective was to determine its effect on neurodevelopmental impairment (NDI) at 24 months' corrected age (CA). This retrospective single-center cohort study included all patients with a gestational age <30 weeks born in 2004/2005 (epoch 1) and 2010/2011 (epoch 2). In epoch 2, we introduced a policy of restriction on IMV and liberalized the use of respiratory stimulants in the delivery room and neonatal intensive care. Data on patient characteristics, respiratory management, short-term outcomes, mortality, BPD, and NDI at 24 months' CA were collected. Four hundred and four preterm infants were included. Compared to those in epoch 1, infants in epoch 2 were less likely to be intubated and the duration of IMV was shorter. Other noninvasive adjuvant therapies such as caffeine, doxapram, and nasal ventilation were more often used during epoch 2. There was a trend to less BPD in epoch 2 compared to epoch 1 (17 vs. 23%, adjusted OR = 0.75, 95% CI: 0.48, 1.16). Mortality did not change over time. The combined outcome death or NDI at 24 months' CA was significantly lower in epoch 2 compared to epoch 1 (24.7 vs. 33.9%, adjusted OR = 0.71, 95% CI: 0.53, 0.97). Restricted use of IMV is feasible in preterm infants and might be associated with a reduced risk of the combined outcome death or NDI at 24 months' CA. Larger studies are needed to confirm these findings. © 2017 The Author(s) Published by S. Karger AG, Basel.

  12. Inflation in a closed universe

    NASA Astrophysics Data System (ADS)

    Ratra, Bharat

    2017-11-01

    To derive a power spectrum for energy density inhomogeneities in a closed universe, we study a spatially-closed inflation-modified hot big bang model whose evolutionary history is divided into three epochs: an early slowly-rolling scalar field inflation epoch and the usual radiation and nonrelativistic matter epochs. (For our purposes it is not necessary to consider a final dark energy dominated epoch.) We derive general solutions of the relativistic linear perturbation equations in each epoch. The constants of integration in the inflation epoch solutions are determined from de Sitter invariant quantum-mechanical initial conditions in the Lorentzian section of the inflating closed de Sitter space derived from Hawking's prescription that the quantum state of the universe only include field configurations that are regular on the Euclidean (de Sitter) sphere section. The constants of integration in the radiation and matter epoch solutions are determined from joining conditions derived by requiring that the linear perturbation equations remain nonsingular at the transitions between epochs. The matter epoch power spectrum of gauge-invariant energy density inhomogeneities is not a power law, and depends on spatial wave number in the way expected for a generalization to the closed model of the standard flat-space scale-invariant power spectrum. The power spectrum we derive appears to differ from a number of other closed inflation model power spectra derived assuming different (presumably non de Sitter invariant) initial conditions.

  13. Cross Calibration of Omnidirectional Orbital Neutron Detectors of Lunar Prospector (LP) and Lunar Exploration Neutron Detector (LEND) by Monte Carlo Simulation

    NASA Astrophysics Data System (ADS)

    Murray, J.; SU, J. J.; Sagdeev, R.; Chin, G.

    2014-12-01

    Introduction:Monte Carlo (MC) simulations have been used to investigate neutron production and leakage from the lunar surface to assess the composition of the lunar soil [1-3]. Orbital measurements of lunar neutron flux have been made by the Lunar Prospector Neutron Spectrometer (LPNS)[4] of the Lunar Prospector mission and the Lunar Exploration Neutron Detector (LEND)[5] of the Lunar Reconnaissance Orbiter mission. While both are cylindrical helium-3 detectors, LEND's SETN (Sensor EpiThermal Neutrons) instrument is shorter, with double the helium-3 pressure than that of LPNS. The two instruments therefore have different angular sensitivities and neutron detection efficiencies. Furthermore, the Lunar Prospector's spin-stabilized design makes its detection efficiency latitude-dependent, while the SETN instrument faces permanently downward toward the lunar surface. We use the GEANT4 Monte Carlo simulation code[6] to investigate the leakage lunar neutron energy spectrum, which follows a power law of the form E-0.9 in the epithermal energy range, and the signals detected by LPNS and SETN in the LP and LRO mission epochs, respectively. Using the lunar neutron flux reconstructed for LPNS epoch, we calculate the signal that would have been observed by SETN at that time. The subsequent deviation from the actual signal observed during the LEND epoch is due to the significantly higher intensity of Galactic Cosmic Rays during the anomalous Solar Minimum of 2009-2010. References: [1] W. C. Feldman, et al., (1998) Science Vol. 281 no. 5382 pp. 1496-1500. [2] Gasnault, O., et al.,(2000) J. Geophys. Res., 105(E2), 4263-4271. [3] Little, R. C., et al. (2003), J. Geophys. Res., 108(E5), 5046. [4]W. C. Feldman, et al., (1999) Nucl. Inst. And Method in Phys. Res. A 422, [5] M. L. Litvak, et al., (2012) J.Geophys. Res. 117, E00H32 [6] J. Allison, et al, (2006) IEEE Trans. on Nucl Sci, Vol 53, No 1.

  14. Identification of scalp EEG circadian variation using a novel correlation sum measure

    NASA Astrophysics Data System (ADS)

    Shahidi Zandi, Ali; Boudreau, Philippe; Boivin, Diane B.; Dumont, Guy A.

    2015-10-01

    Objective. In this paper, we propose a novel method to determine the circadian variation of scalp electroencephalogram (EEG) in both individual and group levels using a correlation sum measure, quantifying self-similarity of the EEG relative energy across waking epochs. Approach. We analysed EEG recordings from central-parietal and occipito-parietal montages in nine healthy subjects undergoing a 72 h ultradian sleep-wake cycle protocol. Each waking epoch (˜1 s) of every nap opportunity was decomposed using the wavelet packet transform, and the relative energy for that epoch was calculated in the desired frequency band using the corresponding wavelet coefficients. Then, the resulting set of energy values was resampled randomly to generate different subsets with equal number of elements. The correlation sum of each subset was then calculated over a range of distance thresholds, and the average over all subsets was computed. This average value was finally scaled for each nap opportunity and considered as a new circadian measure. Main results. According to the evaluation results, a clear circadian rhythm was identified in some EEG frequency ranges, particularly in 4-8 Hz and 10-12 Hz. The correlation sum measure not only was able to disclose the circadian rhythm on the group data but also revealed significant circadian variations in most individual cases, as opposed to previous studies only reporting the circadian rhythms on a population of subjects. Compared to a naive measure based on the EEG absolute energy in the frequency band of interest, the proposed measure showed a clear superiority using both individual and group data. Results also suggested that the acrophase (i.e., the peak) of the circadian rhythm in 10-12 Hz occurs close to the core body temperature minimum. Significance. These results confirm the potential usefulness of the proposed EEG-based measure as a non-invasive circadian marker.

  15. Changes in the Far UV Spectrum of Eta Carinae Near the 2003 Minimum

    NASA Technical Reports Server (NTRS)

    Iping, R. C.; Gull, T. R.; Sonneborn, G.; Massa, D.; Vieira, G. L.; Nielsen, K. E.

    2004-01-01

    High resolution 905-1180 spectra of \\eta Carinae have been obtained with the Far Ultraviolet Spectroscopic Explorer (FUSE) satellite at nine epochs between February 2000 and June 2003 . This period of time extends from the broad maximum up to the very beginning of the minimum of the 5.52-year period initially discovered by A. Damineli. The flux levels were unchanged between February 2000 through February 2003 with minor spectral differences. The X-Ray minimum started on June 29, 2003 . Three observations were accomplished on June 10, June 17 and June 27 leading up to the minimum. Substantial changes were present in the June 10 and June 17 spectra, but a very significant change occurred by June 27, 2003. Longward of 1100A, the overall flux dropped 10 to 30 %. Shortward of 1100A, there are spectral intervals with NO decrease in flux even down to the shortest wavelengths (920--950 ). This indicates that dust absorption has a negligible role in the observed spectral changes and that line absorptions play a major role. Throughout the spectrum there are intervals ranging in width of 3-10A with strong increased absorption. Significant absorptions may be associated with the red portion of the following stellar wind lines: C III 977, O VI 1031,1037, P V 1117, while other absorption features are much broader, more extended and not clearly associated with well-known spectral transitions. Given the complexity of the STIS echelle spectra taken in this period of time, many of these absorption features are likely due to multiple absorption lines

  16. Anon-Pass: Practical Anonymous Subscriptions

    PubMed Central

    Lee, Michael Z.; Dunn, Alan M.; Katz, Jonathan; Waters, Brent; Witchel, Emmett

    2014-01-01

    We present the design, security proof, and implementation of an anonymous subscription service. Users register for the service by providing some form of identity, which might or might not be linked to a real-world identity such as a credit card, a web login, or a public key. A user logs on to the system by presenting a credential derived from information received at registration. Each credential allows only a single login in any authentication window, or epoch. Logins are anonymous in the sense that the service cannot distinguish which user is logging in any better than random guessing. This implies unlinkability of a user across different logins. We find that a central tension in an anonymous subscription service is the service provider’s desire for a long epoch (to reduce server-side computation) versus users’ desire for a short epoch (so they can repeatedly “re-anonymize” their sessions). We balance this tension by having short epochs, but adding an efficient operation for clients who do not need unlinkability to cheaply re-authenticate themselves for the next time period. We measure performance of a research prototype of our protocol that allows an independent service to offer anonymous access to existing services. We implement a music service, an Android-based subway-pass application, and a web proxy, and show that adding anonymity adds minimal client latency and only requires 33 KB of server memory per active user. PMID:24504081

  17. Anon-Pass: Practical Anonymous Subscriptions.

    PubMed

    Lee, Michael Z; Dunn, Alan M; Katz, Jonathan; Waters, Brent; Witchel, Emmett

    2013-12-31

    We present the design, security proof, and implementation of an anonymous subscription service. Users register for the service by providing some form of identity, which might or might not be linked to a real-world identity such as a credit card, a web login, or a public key. A user logs on to the system by presenting a credential derived from information received at registration. Each credential allows only a single login in any authentication window, or epoch . Logins are anonymous in the sense that the service cannot distinguish which user is logging in any better than random guessing. This implies unlinkability of a user across different logins. We find that a central tension in an anonymous subscription service is the service provider's desire for a long epoch (to reduce server-side computation) versus users' desire for a short epoch (so they can repeatedly "re-anonymize" their sessions). We balance this tension by having short epochs, but adding an efficient operation for clients who do not need unlinkability to cheaply re-authenticate themselves for the next time period. We measure performance of a research prototype of our protocol that allows an independent service to offer anonymous access to existing services. We implement a music service, an Android-based subway-pass application, and a web proxy, and show that adding anonymity adds minimal client latency and only requires 33 KB of server memory per active user.

  18. The Cycles of α Centauri

    NASA Astrophysics Data System (ADS)

    Ayres, Thomas R.

    2009-05-01

    The main AB pair of the nearby α Centauri triple system has one of the most extensive X-ray records of any cosmic object, stretching over 30 years. The primary, α Cen A (G2 V), is a near twin of the Sun, with a similarly soft (1-2 MK) corona. The secondary, α Cen B (K1 V), is more active than the Sun, with a generally harder coronal spectrum. Here, more than a decade of spatially resolved measurements from ROSAT, XMM-Newton, and Chandra are compared on a common basis, with careful attention to conversion factors that translate count rates of the different instruments into absolute energy fluxes. For the latter purpose, two epochs of Chandra transmission grating spectra, which fully resolve the binary, were modeled using a differential emission measure formalism. The aggregate time series suggests that α Cen B was near X-ray maximum in the mid-1990s, minimum in the late-1990s, then peaked again in 2004-2005, and more recently has been declining toward another minimum. Meanwhile, α Cen A showed minimal variability 1995-2000, and like the secondary presently is mired in an activity lull (in fact, as seen by XMM-Newton, the primary "fainted" from view in the 2005 time frame). Comparisons between X-ray luminosities in the 0.2-2 keV (6-60 Å) ROSAT "WGACAT" band and a softer counterpart 0.06-1.2 keV (10-200 Å) reinforce the idea that cycle depth is strongly dependent on the energy span of the measurement, and that much of the coronal luminosity of cool-corona objects like the Sun falls at longer wavelengths than are recorded efficiently by contemporary instruments. Consequently, one must be careful in discussing X-ray cycles, their amplitudes, and coronal heating requirements unless one can demonstrate good control over the out-of-band component.

  19. 78 FR 48421 - Publication of North American Datum of 1983 (2011) Epoch 2010.00, North American Datum of 1983...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... of 1983'' (or ``NAD 83''). The new realizations are NAD 83 (2011) epoch 2010.00 [for the North America and Caribbean tectonic plates], NAD 83 (MA11) epoch 2010.00 [for the Mariana tectonic plate] and NAD 83 (PA11) epoch 2010.00 [for the Pacific tectonic plate]. These three realizations supersede all...

  20. Hierarchical porous silver metal using Pluronic F-127 and graphene oxide as reinforcing agents for the reduction of o-nitroaniline to 1, 2-benzenediamine

    NASA Astrophysics Data System (ADS)

    Bano, Mustri; Ahirwar, Devendra; Thomas, Molly; Sheikh, Mehraj Ud Din; Khan, Farid

    2017-04-01

    An elegant method is used to prepare silver monoliths with Pluronic F-127(F-127) as sacrificial template by modified sol-gel method. Si nanoparticles (SiNPs) and graphene oxide (GO) are added in situ to Ag/F-127 hydrogel for the reduction of ο-nitroaniline (ο-NA) to 1, 2-benzenediamine. Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Thermogravimetric analysis (TGA), Raman Spectroscopy, Powder X-Ray Diffraction (PXRD) analysis and Brunauer-Emmett-Teller (BET) Nitrogen adsorption techniques were used for characterization of monoliths. An epoch-making catalytic activity of Ag/F-127/GO monoliths is observed in the reduction of ο-NA to 1, 2-benzenediamine in presence of NaBH4 in aqueous media. The catalyst Ag/F-127/GO took only 2 min which is the minimum time reported so far with significant rate constant claimed itself a leading catalyst for the reduction of ο-NA to 1,2-benzenediamine. Pseudo first order rate constant (k) and Turn over frequency (TOF) values are 0.231 min-1 and 30.053×1019 molecules min-1 respectively suggest that the catalyst has industrial importance. Recyclability and stability of Ag/F-127/GO catalyst are studied successfully up to 10 cycles. Energy of activation (Ea), and thermodynamic parameters viz. activation enthalpy (ΔH≠), activation Gibbs free energy (ΔG≠), and entropy of activation (ΔS≠) were also ascertained. Catalytic activities of Ag/F-127, Ag/F-127/Dextran, Ag/F-127/Trimethylbenzene (TMB), Ag/F-127/SiNPs, and Ag/F-127/Si/GO monoliths were also studied.

  1. "God has sent me to you": Right temporal epilepsy, left prefrontal psychosis.

    PubMed

    Arzy, Shahar; Schurr, Roey

    2016-07-01

    Religious experiences have long been documented in patients with epilepsy, though their exact underlying neural mechanisms are still unclear. Here, we had the rare opportunity to record a delusional religious conversion in real time in a patient with right temporal lobe epilepsy undergoing continuous video-EEG. In this patient, a messianic revelation experience occurred several hours after a complex partial seizure of temporal origin, compatible with postictal psychosis (PIP). We analyzed the recorded resting-state EEG epochs separately for each of the conventional frequency bands. Topographical analysis of the bandpass filtered EEG epochs revealed increased activity in the low-gamma range (30-40Hz) during religious conversion compared with activity during the patient's habitual state. The brain generator underlying this activity was localized to the left prefrontal cortex. This suggests that religious conversion in PIP is related to control mechanisms in the prefrontal lobe-related processes rather than medial temporal lobe-related processes. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. A study of the kinematic dynamo equation with time-dependent coefficients

    NASA Technical Reports Server (NTRS)

    Ko, Chung-Ming

    1990-01-01

    During an active star formation epoch the interstellar medium of a galaxy is in a hyperactive state, and the average turbulent velocity is higher than in the long periods between star formation epochs. The galactic magnetic field generated by dynamo action depends strongly on the turbulent velocity, so that generation of magnetic field should vary with star formation activity. This paper is a preliminary study of the kinematic dynamo equation with time-dependent coefficients simulating the time dependence of the star formation activities. Ko and Parker argued in a simple model that the thickness of the dynamo region is the most sensitive dynamo parameter. The present work shows that the effect of inflating the galactic disk suddenly is to transform a stationary magnetic field into a growing field while keeping the profile more or less intact. Plane wave solutions for a dynamo with power-law time-dependent parameters show that the field may decay first and then grow, and vice versa, which is quite different from a constant parameter dynamo.

  3. Epoch length to accurately estimate the amplitude of interference EMG is likely the result of unavoidable amplitude cancellation

    PubMed Central

    Keenan, Kevin G.; Valero-Cuevas, Francisco J.

    2008-01-01

    Researchers and clinicians routinely rely on interference electromyograms (EMGs) to estimate muscle forces and command signals in the neuromuscular system (e.g., amplitude, timing, and frequency content). The amplitude cancellation intrinsic to interference EMG, however, raises important questions about how to optimize these estimates. For example, what should the length of the epoch (time window) be to average an EMG signal to reliably estimate muscle forces and command signals? Shorter epochs are most practical, and significant reductions in epoch have been reported with high-pass filtering and whitening. Given that this processing attenuates power at frequencies of interest (< 250 Hz), however, it is unclear how it improves the extraction of physiologically-relevant information. We examined the influence of amplitude cancellation and high-pass filtering on the epoch necessary to accurately estimate the “true” average EMG amplitude calculated from a 28 s EMG trace (EMGref) during simulated constant isometric conditions. Monte Carlo iterations of a motor-unit model simulating 28 s of surface EMG produced 245 simulations under 2 conditions: with and without amplitude cancellation. For each simulation, we calculated the epoch necessary to generate average full-wave rectified EMG amplitudes that settled within 5% of EMGref. For the no-cancellation EMG, the necessary epochs were short (e.g., < 100 ms). For the more realistic interference EMG (i.e., cancellation condition), epochs shortened dramatically after using high-pass filter cutoffs above 250 Hz, producing epochs short enough to be practical (i.e., < 500 ms). We conclude that the need to use long epochs to accurately estimate EMG amplitude is likely the result of unavoidable amplitude cancellation, which helps to clarify why high-pass filtering (> 250 Hz) improves EMG estimates. PMID:19081815

  4. The Caltech-NRAO Stripe 82 Survey (CNSS) Paper. I. The Pilot Radio Transient Survey in 50 Deg.(exp. 2)

    NASA Technical Reports Server (NTRS)

    Mooley, K. P.; Hallinan, G.; Bourke, S.; Horesh, A.; Myers, S. T.; Frail, D. A.; Kulkarni, S. R.; Levitan, D. B.; Kasliwal, M. M.; Cenko, S. B.; hide

    2016-01-01

    We have commenced a multiyear program, the Caltech-NRAO Stripe 82 Survey (CNSS), to search for radio transients with the Jansky VLA in the Sloan Digital Sky Survey Stripe 82 region. The CNSS will deliver five epochs over the entire approx. 270 deg.(exp. 2) of Stripe 82, an eventual deep combined map with an rms noise of approx. 40 proper motion epoch y and catalogs at a frequency of 3 GHz, and having a spatial resolution of 3 inches. This first paper presents the results from an initial pilot survey of a 50 deg.(exp. 2) region of Stripe 82, involving four epochs spanning logarithmic timescales between 1 week and 1.5 yr, with the combined map having a median rms noise of 35 proper motion epoch y. This pilot survey enabled the development of the hardware and software for rapid data processing, as well as transient detection and follow-up, necessary for the full 270 deg.(exp. 2) survey. Data editing, calibration, imaging, source extraction, cataloging, and transient identification were completed in a semi-automated fashion within 6 hr of completion of each epoch of observations, using dedicated computational hardware at the NRAO in Socorro and custom-developed data reduction and transient detection pipelines. Classification of variable and transient sources relied heavily on the wealth of multiwavelength legacy survey data in the Stripe 82 region, supplemented by repeated mapping of the region by the Palomar Transient Factory. A total of 3.9(+0.5%/-0.9%) of the few thousand detected point sources werefound to vary by greater than 30%, consistent with similar studies at 1.4 and 5 GHz. Multiwavelength photometric data and light curves suggest that the variability is mostly due to shock-induced flaring in the jets of active galactic nuclei (AGNs). Although this was only a pilot survey, we detected two bona fide transients, associated with an RS CVn binary and a dKe star. Comparison with existing legacy survey data (FIRST, VLA-Stripe 82) revealed additional highly variable and transient sources on timescales between 5 and 20 yr, largely associated with renewed AGN activity. The rates of such AGNs possibly imply episodes of enhanced accretion and jet activity occurring once every approx. 40,000 yr in these galaxies. We compile the revised radio transient rates and make recommendations for future transient surveys and joint radio-optical experiments.

  5. Fitbit Charge HR Wireless Heart Rate Monitor: Validation Study Conducted Under Free-Living Conditions.

    PubMed

    Gorny, Alexander Wilhelm; Liew, Seaw Jia; Tan, Chuen Seng; Müller-Riemenschneider, Falk

    2017-10-20

    Many modern smart watches and activity trackers feature an optical sensor that estimates the wearer's heart rate. Recent studies have evaluated the performance of these consumer devices in the laboratory. The objective of our study was to examine the accuracy and sensitivity of a common wrist-worn tracker device in measuring heart rates and detecting 1-min bouts of moderate to vigorous physical activity (MVPA) under free-living conditions. Ten healthy volunteers were recruited from a large university in Singapore to participate in a limited field test, followed by a month of continuous data collection. During the field test, each participant would wear one Fitbit Charge HR activity tracker and one Polar H6 heart rate monitor. Fitbit measures were accessed at 1-min intervals, while Polar readings were available for 10-s intervals. We derived intraclass correlation coefficients (ICCs) for individual participants comparing heart rate estimates. We applied Centers for Disease Control and Prevention heart rate zone cut-offs to ascertain the sensitivity and specificity of Fitbit in identifying 1-min epochs falling into MVPA heart rate zone. We collected paired heart rate data for 2509 1-min epochs in 10 individuals under free-living conditions of 3 to 6 hours. The overall ICC comparing 1-min Fitbit measures with average 10-s Polar H6 measures for the same epoch was .83 (95% CI .63-.91). On average, the Fitbit tracker underestimated heart rate measures by -5.96 bpm (standard error, SE=0.18). At the low intensity heart rate zone, the underestimate was smaller at -4.22 bpm (SE=0.15). This underestimate grew to -16.2 bpm (SE=0.74) in the MVPA heart rate zone. Fitbit devices detected 52.9% (192/363) of MVPA heart rate zone epochs correctly. Positive and negative predictive values were 86.1% (192/223) and 92.52% (2115/2286), respectively. During subsequent 1 month of continuous data collection (270 person-days), only 3.9% of 1-min epochs could be categorized as MVPA according to heart rate zones. This measure was affected by decreasing wear time and adherence over the period of follow-up. Under free-living conditions, Fitbit trackers are affected by significant systematic errors. Improvements in tracker accuracy and sensitivity when measuring MVPA are required before they can be considered for use in the context of exercise prescription to promote better health. ©Alexander Wilhelm Gorny, Seaw Jia Liew, Chuen Seng Tan, Falk Müller-Riemenschneider. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 20.10.2017.

  6. Patients with mild cognitive impairment have an abnormal upper-alpha event-related desynchronization/synchronization (ERD/ERS) during a task of temporal attention.

    PubMed

    Caravaglios, Giuseppe; Muscoso, Emma Gabriella; Di Maria, Giulia; Costanzo, Erminio

    2015-03-01

    There are several evidences indicating that an impairment in attention-executive functions is present in prodromal Alzheimer's disease and predict future global cognitive decline. In particular, the issue of temporal orienting of attention in patients with mild cognitive impairment (MCI) due to Alzheimer's disease has been overlooked. The present research aimed to explore whether subtle deficits of cortical activation are present in these patients early in the course of the disease. We studied the upper-alpha event-related synchronization/desynchronization phenomenon during a paradigm of temporal orientation of attention. MCI patients (n = 27) and healthy elderly controls (n = 15) performed a task in which periodically omitted tones had to be predicted and their virtual onset time had to be marked by pressing a button. Single-trial responses were measured, respectively, before and after the motor response. Then, upper-alpha responses were compared to upper-alpha power during eyes-closed resting state. The time course of the task was characterized by two different behavioral conditions: (1) a pre-event epoch, in which the subject awaited the virtual onset of the omitted tone, (2) a post-event epoch (after button pressing), in which the subject was in a post-motor response condition. The principal findings are: (1) during the waiting epoch, only healthy elderly had an upper-alpha ERD at the level of both temporal and posterior brain regions; (2) during the post-motor epoch, the aMCI patients had a weaker upper-alpha ERS on prefrontal regions; (3) only healthy elderly showed a laterality effect: (a) during the waiting epoch, the upper-alpha ERD was greater at the level of the right posterior-temporal lead; during the post-motor epoch, the upper alpha ERS was greater on the left prefrontal lead. The relevance of these findings is that the weaker upper-alpha response observed in aMCI patients is evident even if the accuracy of the behavioral performance (i.e., button pressing) is still spared. This abnormal upper-alpha response might represent an early biomarker of the attention-executive network impairment in MCI due to Alzheimer's disease.

  7. Tonic and phasic co-variation of peripheral arousal indices in infants

    PubMed Central

    Wass, S.V.; de Barbaro, K.; Clackson, K.

    2015-01-01

    Tonic and phasic differences in peripheral autonomic nervous system (ANS) indicators strongly predict differences in attention and emotion regulation in developmental populations. However, virtually all previous research has been based on individual ANS measures, which poses a variety of conceptual and methodlogical challenges to comparing results across studies. Here we recorded heart rate, electrodermal activity (EDA), pupil size, head movement velocity and peripheral accelerometry concurrently while a cohort of 37 typical 12-month-old infants completed a mixed assessment battery lasting approximately 20 min per participant. We analysed covariation of these autonomic indices in three ways: first, tonic (baseline) arousal; second, co-variation in spontaneous (phasic) changes during testing; third, phasic co-variation relative to an external stimulus event. We found that heart rate, head velocity and peripheral accelerometry showed strong positive co-variation across all three analyses. EDA showed no co-variation in tonic activity levels but did show phasic positive co-variation with other measures, that appeared limited to sections of high but not low general arousal. Tonic pupil size showed significant positive covariation, but phasic pupil changes were inconsistent. We conclude that: (i) there is high covariation between autonomic indices in infants, but that EDA may only be sensitive at extreme arousal levels, (ii) that tonic pupil size covaries with other indices, but does not show predicted patterns of phasic change and (iii) that motor activity appears to be a good proxy measure of ANS activity. The strongest patterns of covariation were observed using epoch durations of 40 s per epoch, although significant covariation between indices was also observed using shorter epochs (1 and 5 s). PMID:26316360

  8. The where and how of attention-based rehearsal in spatial working memory.

    PubMed

    Postle, B R; Awh, E; Jonides, J; Smith, E E; D'Esposito, M

    2004-07-01

    Rehearsal in human spatial working memory is accomplished, in part, via covert shifts of spatial selective attention to memorized locations ("attention-based rehearsal"). We addressed two outstanding questions about attention-based rehearsal: the topography of the attention-based rehearsal effect, and the mechanism by which it operates. Using event-related fMRI and a procedure that randomized the presentation of trials with delay epochs that were either filled with a flickering checkerboard or unfilled, we localized the effect to extrastriate areas 18 and 19, and confirmed its absence in striate cortex. Delay-epoch activity in these extrastriate regions, as well as in superior parietal lobule and intraparietal sulcus, was also lateralized on unfilled trials, suggesting that attention-based rehearsal produces a baseline shift in areas representing the to-be-remembered location in space. No frontal regions (including frontal eye fields) demonstrated lateralized activity consistent with a role in attention-based rehearsal.

  9. Real-time forecasting of ICME shock arrivals at L1 during the "April Fool’s Day" epoch: 28 March  21 April 2001

    NASA Astrophysics Data System (ADS)

    Sun, W.; Dryer, M.; Fry, C. D.; Deehr, C. S.; Smith, Z.; Akasofu, S.-I.; Kartalev, M. D.; Grigorov, K. G.

    2002-07-01

    The Sun was extremely active during the "April Fool’s Day" epoch of 2001. We chose this period between a solar flare on 28 March 2001 to a final shock arrival at Earth on 21 April 2001. The activity consisted of two presumed helmet-streamer blowouts, seven M-class flares, and nine X-class flares, the last of which was behind the west limb. We have been experimenting since February 1997 with real-time, end-to-end forecasting of interplanetary coronal mass ejection (ICME) shock arrival times. Since August 1998, these forecasts have been distributed in real-time by e-mail to a list of interested scientists and operational USAF and NOAA forecasters. They are made using three different solar wind models. We describe here the solar events observed during the April Fool’s 2001 epoch, along with the predicted and actual shock arrival times, and the ex post facto correction to the real-time coronal shock speed observations. It appears that the initial estimates of coronal shock speeds from Type II radio burst observations and coronal mass ejections were too high by as much as 30%. We conclude that a 3-dimensional coronal density model should be developed for application to observations of solar flares and their Type II radio burst observations.

  10. Impact of Sommerfeld enhancement on helium reionization via WIMP dark matter

    NASA Astrophysics Data System (ADS)

    Bandyopadhyay, Bidisha; Schleicher, Dominik R. G.

    2018-03-01

    Dark matter annihilation can have a strong impact on many astrophysical processes in the Universe. In the case of Sommerfeld-enhanced annihilation cross sections, the annihilation rates are enhanced at late times, thus enhancing the potential annihilation signatures. We here calculate the Sommerfeld-enhanced annihilation signatures during the epoch of helium reionization, the epoch where helium becomes fully ionized due to energetic photons. When considering the upper limits on the energy injection from the CMB, we find that the resulting abundance of He++ becomes independent of the dark matter particle mass. The resulting enhancement compared to a standard scenario is thus 1-2 orders of magnitude higher. For realistic scenarios compatible with CMB constraints, there is no significant shift in the epoch of helium reionization, which is completed between redshifts 3 and 4. While it is thus difficult to disentangle dark matter annihilation from astrophysical contributions (active galactic nuclei), a potential detection of dark matter particles and its interactions using the Large Hadron Collider (LHC) would allow one to quantify the dark matter contribution.

  11. Superposed epoch analysis and storm statistics from 25 years of the global geomagnetic disturbance index, USGS-Dst

    USGS Publications Warehouse

    Gannon, J.L.

    2012-01-01

    Statistics on geomagnetic storms with minima below -50 nanoTesla are compiled using a 25-year span of the 1-minute resolution disturbance index, U.S. Geological Survey Dst. A sudden commencement, main phase minimum, and time between the two has a magnitude of 35 nanoTesla, -100 nanoTesla, and 12 hours, respectively, at the 50th percentile level. The cumulative distribution functions for each of these features are presented. Correlation between sudden commencement magnitude and main phase magnitude is shown to be low. Small, medium, and large storm templates at the 33rd, 50th, and 90th percentile are presented and compared to real examples. In addition, the relative occurrence of rates of change in Dst are presented.

  12. The effect of epoch length on time and frequency domain parameters of electromyographic and mechanomyographic signals.

    PubMed

    Keller, Joshua L; Housh, Terry J; Camic, Clayton L; Bergstrom, Haley C; Smith, Doug B; Smith, Cory M; Hill, Ethan C; Schmidt, Richard J; Johnson, Glen O; Zuniga, Jorge M

    2018-06-01

    The selection of epoch lengths affects the time and frequency resolution of electromyographic (EMG) and mechanomyographic (MMG) signals, as well as decisions regarding the signal processing techniques to use for determining the power density spectrum. No previous studies, however, have examined the effects of epoch length on parameters of the MMG signal. The purpose of this study was to examine the differences between epoch lengths for EMG amplitude, EMG mean power frequency (MPF), MMG amplitude, and MMG MPF from the VL and VM muscles during MVIC muscle actions as well as at each 10% of the time to exhaustion (TTE) during a continuous isometric muscle action of the leg extensors at 50% of MVIC. During the MVIC trial, there were no significant (p > 0.05) differences between epoch lengths (0.25, 0.50, 1.00, and 2.00-s) for mean absolute values for any of the EMG or MMG parameters. During the submaximal, sustained muscle action, however, absolute MMG amplitude and MMG MPF were affected by the length of epoch. All epoch related differences were eliminated by normalizing the absolute values to MVIC. These findings supported normalizing EMG and MMG parameter values to MVIC and utilizing epoch lengths that ranged from 0.25 to 2.00-s. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Changes in neurodevelopmental outcomes at 18 to 22 months' corrected age among infants of less than 25 weeks' gestational age born in 1993-1999.

    PubMed

    Hintz, Susan R; Kendrick, Douglas E; Vohr, Betty R; Poole, W Kenneth; Higgins, Rosemary D

    2005-06-01

    Increased survival rates for extremely preterm, extremely low birth weight infants during the postsurfactant era have been reported, but data on changes in neurosensory and developmental impairments are sparse. To compare neuromotor and neurodevelopmental outcomes at 18 to 22 months' corrected age for infants of <25 weeks' estimated gestational age (EGA) who were born in the 1990s. This was a multicenter, retrospective, comparative analysis of infants of <25 weeks' EGA, with birth weights of 501 to 1000 g, born between January 1993 and June 1996 (epoch I) or between July 1996 and December 1999 (epoch II), in the National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental assessments were performed at 18 to 22 months' corrected age. Logistic-regression models were constructed to evaluate the independent risk of cerebral palsy, Mental Development Index of <70, Psychomotor Development Index of <70, and neurodevelopmental impairment. A total of 366 patients in epoch I and 473 patients in epoch II were evaluated. Prenatal steroid use, cesarean section, surfactant treatment, bronchopulmonary dysplasia, and severe retinopathy of prematurity were more likely in epoch II, whereas Apgar scores of <5 at 5 minutes, patent ductus arteriosus, and severe intraventricular hemorrhage were more likely in epoch I. The prevalences of cerebral palsy, Psychomotor Development Index of <70, and neurodevelopmental impairment were similar between epochs. The prevalences of Mental Development Index of <70 were 40% for epoch I and 47% for epoch II. Regression analysis revealed that epoch II was an independent risk factor for Mental Developmental Index of <70 (epoch I versus II: odds ratio: 0.63; 95% confidence interval: 0.45-0.87) but not for other outcomes. Early childhood neurodevelopmental outcomes among infants of <25 weeks' EGA are not improving in the postsurfactant era, despite more aggressive perinatal and neonatal treatment. Later childhood follow-up assessment is needed to delineate trends in severe cognitive impairment in this extremely high-risk group.

  14. V405 ANDROMEDA REVISITED

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ribeiro, T.; Baptista, R.; Kafka, S.

    We present a multi-epoch time-resolved high-resolution optical spectroscopy study of the short-period (P{sub orb} = 11.2 hr) eclipsing M0V+M5V RS CVn binary V405 Andromeda. By means of indirect imaging techniques, namely Doppler imaging, we study the surface activity features of the M0V component of the system. A modified version of a Doppler imaging code, which takes into account the tidal distortion of the surface of the star, is applied to the multi-epoch data set in order to provide indirect images of the stellar surface. The multi-epoch surface brightness distributions show a low intensity 'belt' of spots at latitudes {+-}40{sup 0}more » and a noticeable absence of high latitude features or polar spots on the primary star of V405 Andromeda. They also reveal slow evolution of the spot distribution over {approx}4 yr. An entropy landscape procedure is used in order to find the set of binary parameters that lead to the smoothest surface brightness distributions. As a result, we find M{sub 1} = 0.51 {+-} 0.03 M{sub sun}, M{sub 2} = 0.21 {+-} 0.01 M{sub sun}, R{sub 1} = 0.71 {+-} 0.01 R{sub sun}, and an inclination i = 65{sup 0} {+-} 1{sup 0}. The resulting systemic velocity is distinct for different epochs, raising the possibility of the existence of a third body in the system.« less

  15. Reducing door-to-needle times using Toyota's lean manufacturing principles and value stream analysis.

    PubMed

    Ford, Andria L; Williams, Jennifer A; Spencer, Mary; McCammon, Craig; Khoury, Naim; Sampson, Tomoko R; Panagos, Peter; Lee, Jin-Moo

    2012-12-01

    Earlier tissue-type plasminogen activator (tPA) treatment for acute ischemic stroke increases efficacy, prompting national efforts to reduce door-to-needle times. We used lean process improvement methodology to develop a streamlined intravenous tPA protocol. In early 2011, a multidisciplinary team analyzed the steps required to treat patients with acute ischemic stroke with intravenous tPA using value stream analysis (VSA). We directly compared the tPA-treated patients in the "pre-VSA" epoch with the "post-VSA" epoch with regard to baseline characteristics, protocol metrics, and clinical outcomes. The VSA revealed several tPA protocol inefficiencies: routing of patients to room, then to CT, then back to the room; serial processing of workflow; and delays in waiting for laboratory results. On March 1, 2011, a new protocol incorporated changes to minimize delays: routing patients directly to head CT before the patient room, using parallel process workflow, and implementing point-of-care laboratories. In the pre and post-VSA epochs, 132 and 87 patients were treated with intravenous tPA, respectively. Compared with pre-VSA, door-to-needle times and percent of patients treated ≤60 minutes from hospital arrival were improved in the post-VSA epoch: 60 minutes versus 39 minutes (P<0.0001) and 52% versus 78% (P<0.0001), respectively, with no change in symptomatic hemorrhage rate. Lean process improvement methodology can expedite time-dependent stroke care without compromising safety.

  16. Identifying individual sleep apnea/hypoapnea epochs using smartphone-based pulse oximetry.

    PubMed

    Garde, Ainara; Dekhordi, Parastoo; Ansermino, J Mark; Dumont, Guy A

    2016-08-01

    Sleep apnea, characterized by frequent pauses in breathing during sleep, poses a serious threat to the healthy growth and development of children. Polysomnography (PSG), the gold standard for sleep apnea diagnosis, is resource intensive and confined to sleep laboratories, thus reducing its accessibility. Pulse oximetry alone, providing blood oxygen saturation (SpO2) and blood volume changes in tissue (PPG), has the potential to identify children with sleep apnea. Thus, we aim to develop a tool for at-home sleep apnea screening that provides a detailed and automated 30 sec epoch-by-epoch sleep apnea analysis. We propose to extract features characterizing pulse oximetry (SpO2 and pulse rate variability [PRV], a surrogate measure of heart rate variability) to create a multivariate logistic regression model that identifies epochs containing apnea/hypoapnea events. Overnight pulse oximetry was collected using a smartphone-based pulse oximeter, simultaneously with standard PSG from 160 children at the British Columbia Children's hospital. The sleep technician manually scored all apnea/hypoapnea events during the PSG study. Based on these scores we labeled each epoch as containing or not containing apnea/hypoapnea. We randomly divided the subjects into training data (40%), used to develop the model applying the LASSO method, and testing data (60%), used to validate the model. The developed model was assessed epoch-by-epoch for each subject. The test dataset had a median area under the receiver operating characteristic (ROC) curve of 81%; the model provided a median accuracy of 74% sensitivity of 75%, and specificity of 73% when using a risk threshold similar to the percentage of apnea/hypopnea epochs. Thus, providing a detailed epoch-by-epoch analysis with at-home pulse oximetry alone is feasible with accuracy, sensitivity and specificity values above 73% However, the performance might decrease when analyzing subjects with a low number of apnea/hypoapnea events.

  17. Staging Sleep in Polysomnograms: Analysis of Inter-Scorer Variability

    PubMed Central

    Younes, Magdy; Raneri, Jill; Hanly, Patrick

    2016-01-01

    Study Objectives: To determine the reasons for inter-scorer variability in sleep staging of polysomnograms (PSGs). Methods: Fifty-six PSGs were scored (5-stage sleep scoring) by 2 experienced technologists, (first manual, M1). Months later, the technologists edited their own scoring (second manual, M2) based upon feedback from the investigators that highlighted differences between their scoring. The PSGs were then scored with an automatic system (Auto) and the technologists edited them, epoch-by-epoch (Edited-Auto). This resulted in 6 different manual scores for each PSG. Epochs were classified as scorer errors (one M1 score differed from the other 5 scores), scorer bias (all 3 scores of each technologist were similar, but differed from the other technologist) and equivocal (sleep scoring was inconsistent within and between technologists). Results: Percent agreement after M1 was 78.9% ± 9.0% and was unchanged after M2 (78.1% ± 9.7%) despite numerous edits (≈40/PSG) by the scorers. Agreement in Edited-Auto was higher (86.5% ± 6.4%, p < 1E−9). Scorer errors (< 2% of epochs) and scorer bias (3.5% ± 2.3% of epochs) together accounted for < 20% of M1 disagreements. A large number of epochs (92 ± 44/PSG) with scoring agreement in M1 were subsequently changed in M2 and/or Edited-Auto. Equivocal epochs, which showed scoring inconsistency, accounted for 28% ± 12% of all epochs, and up to 76% of all epochs in individual patients. Disagreements were largely between awake/NREM, N1/N2, and N2/N3 sleep. Conclusion: Inter-scorer variability is largely due to epochs that are difficult to classify. Availability of digitally identified events (e.g., spindles) or calculated variables (e.g., depth of sleep, delta wave duration) during scoring may greatly reduce scoring variability. Citation: Younes M, Raneri J, Hanly P. Staging sleep in polysomnograms: analysis of inter-scorer variability. J Clin Sleep Med 2016;12(6):885–894. PMID:27070243

  18. Orbitally-resolved SST Changes during the EOT: Results from IODP 342 Expedition

    NASA Astrophysics Data System (ADS)

    Liu, Z.; He, Y.; Wilson, P. A.; Pagani, M.

    2014-12-01

    Sea surface temperature (SST) changes during the Eocene-Oligocene climate transition were characterized by substantial cooling at high latitudes and less cooling in low latitudes, with little information from mid-latitudes so far. Taking advantage of the newly retrieved drift sediments from the IODP 342 Expedition, we aim to reconstruct SST changes at the mid-latitude Newfoundland region, at an unprecedented orbital resolution from Site U1411. During the period investigated, 32-36 Ma, the alkenone UK'37 values range from 0.65 to 0.95, with values all greater than 0.80 before the transition and lower values (<0.80) occurring approximately at the eccentricity minimum nodes after the transition. No immediate cooling associated with Oi-1 glaciation was observed. During the Oligocene, SSTs during warm epochs (corresponding to eccentricity maxima) were not significantly cooler than before. Overall, SST fluctuations appear to be modulated by orbital changes throughout the record, although more apparent due to larger amplitude of SST variability after the transition. We thus hypothesize that the mid-latitude Newfoundland region was largely bathed by low-latitude warm waters during the transition and that polar waters (fronts) reached to the region occasionally at periods of eccentricity minimum nodes during the Oligocene.

  19. Rapid ambiguity resolution over medium-to-long baselines based on GPS/BDS multi-frequency observables

    NASA Astrophysics Data System (ADS)

    Gong, Xiaopeng; Lou, Yidong; Liu, Wanke; Zheng, Fu; Gu, Shengfeng; Wang, Hua

    2017-02-01

    Medium-long baseline RTK positioning generally needs a long initial time to find an accurate position due to non-negligible atmospheric delay residual. In order to shorten the initial or re-convergence time, a rapid phase ambiguity resolution method is employed based on GPS/BDS multi-frequency observables in this paper. This method is realized by two steps. First, double-differenced un-combined observables (i.e., L1/L2 and B1/B2/B3 observables) are used to obtain a float solution with atmospheric delay estimated as random walk parameter by using Kalman filter. This model enables an easy and consistent implementation for different systems and different frequency observables and can readily be extended to use more satellite navigation systems (e.g., Galileo, QZSS). Additional prior constraints for atmospheric information can be quickly added as well, because atmospheric delay is parameterized. Second, in order to fix ambiguity rapidly and reliably, ambiguities are divided into three types (extra-wide-lane (EWL), wide-lane (WL) and narrow-lane (NL)) according to their wavelengths and are to be fixed sequentially by using the LAMBDA method. Several baselines ranging from 61 km to 232 km collected by Trimble and Panda receivers are used to validate the method. The results illustrate that it only takes approximately 1, 2 and 6 epochs (30 s intervals) to fix EWL, WL and NL ambiguities, respectively. More epochs' observables are needed to fix WL and NL ambiguity around local time 14:00 than other time mainly due to more active ionosphere activity. As for the re-convergence time, the simulated results show that 90% of epochs can be fixed within 2 epochs by using prior atmospheric delay information obtained from previously 5 min. Finally, as for positioning accuracy, meter, decimeter and centimeter level positioning results are obtained according to different ambiguity resolution performances, i.e., EWL, WL and NL fixed solutions.

  20. Impact of umbilical cord milking and pasteurized donor human milk on necrotizing enterocolitis: a retrospective review.

    PubMed

    Sekhon, Mehtab K; Yoder, Bradley A

    2018-05-08

    Necrotizing enterocolitis (NEC) is a serious complication of prematurity. Our objective was to evaluate the impact of an umbilical cord milking protocol (UCM) and pasteurized donor human milk (PDHM) on NEC rates in infants less than 30 weeks gestational age from January 1, 2010 to September 30, 2016. We hypothesized an incremental decrease in NEC after each intervention. We performed a retrospective review of 638 infants born less than 30 weeks gestational age. Infants were grouped into three epochs: pre-UCM/pre-PDHM (Epoch 1, n = 159), post-UCM/pre-PDHM (Epoch 2, n = 133), and post-UCM/post-PDHM (Epoch 3, n = 252). The incidence of NEC, surgical NEC, and NEC/death were compared. Logistic regression was used to determine independent significance of time epoch, gestational age, birth weight, and patent ductus arteriosus for NEC, surgical NEC, and death/NEC. At birth, infants in Epoch 1 were younger than Epoch 2 and 3 (26.8 weeks versus 27.3 and 27.2, respectively, P = 0.036) and smaller (910 g versus 1012 and 983, respectively, P = 0.012). Across epochs, there was a significant correlation between patent ductus arteriosus treatment and NEC rate (P < 0.001, Cochran-Mantel-Haenszel). There was a significant decrease in rates of NEC, surgical NEC, and NEC/death between groups. Logistic regression showed this as significant for rates of NEC and surgical NEC between Epoch 1 and 3. Patent ductus arteriosus was a significant variable affecting the incidence of NEC, but not surgical NEC or death/NEC. An umbilical cord milking protocol and pasteurized donor human milk availability was associated with decreased rates of NEC and surgical NEC. This suggests an additive effect of these interventions in preventing NEC.

  1. Metabolic Thresholds and Validated Accelerometer Cutoff Points for the Actigraph GT1M in Young Children Based on Measurements of Locomotion and Play Activities

    ERIC Educational Resources Information Center

    Jimmy, Gerda; Dossegger, Alain; Seiler, Roland; Mader, Urs

    2012-01-01

    The purpose of the current study was to determine metabolic thresholds and subsequent activity intensity cutoff points for the ActiGraph GT1M with various epochs spanning from 5 to 60 sec in young children. Twenty-two children, aged 4 to 9 years, performed 10 different activities including locomotion and play activities. Energy expenditure was…

  2. The convective photosphere of the red supergiant CE Tauri. I. VLTI/PIONIER H-band interferometric imaging

    NASA Astrophysics Data System (ADS)

    Montargès, M.; Norris, R.; Chiavassa, A.; Tessore, B.; Lèbre, A.; Baron, F.

    2018-06-01

    Context. Red supergiant stars are one of the latest stages in the evolution of massive stars. Their photospheric convection may play an important role in the launching mechanism of their mass loss; however, its characteristics and dynamics are still poorly constrained. Aims: By observing red supergiant stars with near infrared interferometry at different epochs, we expect to reveal the evolution of bright convective features on their stellar surface. Methods: We observed the M2Iab-Ib red supergiant star CE Tau with the VLTI/PIONIER instrument in the H band at two different epochs separated by one month. Results: We derive the angular diameter of the star and basic stellar parameters, and reconstruct two reliable images of its H-band photosphere. The contrast of the convective pattern of the reconstructed images is 5 ± 1% and 6 ± 1% for our two epochs of observation. Conclusions: The stellar photosphere shows few changes between the two epochs. The contrast of the convective pattern is below the average contrast variations obtained on 30 randomly chosen snapshots of the best matching 3D radiative hydrodynamics simulation: 23 ± 1% for the original simulation images and 16 ± 1% for the maps degraded to the reconstruction resolution. We offer two hypotheses to explain this observation. CE Tau may be experiencing a quiet convective activity episode or it could be a consequence of its warmer effective temperature (hence its smaller radius) compared to the simulation. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programs 298.D-5005(A) and 298.D-5005(B).Reconstructed images as FITS files and basic stellar parameters are available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/614/A12Animated gif of the two epochs is available at http://https://www.aanda.org

  3. The impact of a dedicated patent ductus arteriosus ligation team on neonatal health-care outcomes.

    PubMed

    Resende, M H F; More, K; Nicholls, D; Ting, J; Jain, A; McNamara, P J

    2016-06-01

    The decision to perform patent ductus arteriosus (PDA) ligation is controversial. Patient selection is oftentimes poorly standardized, leading to delays in referral and inappropriate intervention. A system for PDA ligation categorization and triaging process was introduced in 2006 at a quaternary hospital in Canada to streamline referrals and enhance perioperative care. We aimed to evaluate the impact of this dedicated PDA ligation triaging system comparing pre- and postimplementation of this system. We performed a retrospective chart review. Demographic and cardiorespiratory data of neonates ⩽30 weeks gestation age at birth, who were referred for and/or had a PDA ligation performed during two distinct epochs (EPOCH 1 (2003 to 2005) and EPOCH 2 (2010 to 2012)), were analyzed. All surgeries were performed at The Hospital for Sick Children, the regional referral center for PDA ligation. The primary outcome was incidence of PDA ligation and procedural cancellations. Secondary outcomes included postoperative need for cardiovascular or respiratory support. Subgroup analysis was performed in neonates <1000 vs >1000 g at the time of surgery during both epochs. A total of 198 neonates underwent surgery with no difference in baseline demographics between epochs. The incidence of PDA ligation as a proportion of total live births under 30 weeks in Central East Region of Ontario was lower in the second epoch (EPOCH 1: 117/1092 (10.7%) vs EPOCH 2: 81/1520 (5.3%)). During the second epoch, 24% of referrals for surgery were canceled after review by our PDA ligation team. There were no overall differences in the proportion of neonates with oxygenation failure, ventilation failure or Post-Ligation Cardiac Syndrome (PLCS), after surgery, between epochs. The proportion of neonates who developed systemic hypotension was higher in patients <1000 g (n=34 (34%) vs n=17 (17.4%), P=0.01) at the time of surgery. In addition, we identified a reduction in the proportion of neonates <1000 g who developed PLCS in EPOCH 2. On the contrary, there was an increase in the proportion of neonates >1000 g who developed ventilation failure in EPOCH 2. The presence of dedicated triaging and management system enhances efficiency of referral process through careful selection of patients for PDA ligation and optimizes perioperative management. We demonstrated a reduction in the incidence of PDA ligation without any negative impact on short-term neonatal morbidity. The use of targeted neonatal echocardiography in the assessment of PDA shunt volume and guiding postoperative decision making is likely to have contributed to these findings.

  4. Solar Drivers of 11-yr and Long-Term Cosmic Ray Modulation

    NASA Technical Reports Server (NTRS)

    Cliver, E. W.; Richardson, I. G.; Ling, A. G.

    2011-01-01

    In the current paradigm for the modulation of galactic cosmic rays (GCRs), diffusion is taken to be the dominant process during solar maxima while drift dominates at minima. Observations during the recent solar minimum challenge the pre-eminence of drift: at such times. In 2009, the approx.2 GV GCR intensity measured by the Newark neutron monitor increased by approx.5% relative to its maximum value two cycles earlier even though the average tilt angle in 2009 was slightly larger than that in 1986 (approx.20deg vs. approx.14deg), while solar wind B was significantly lower (approx.3.9 nT vs. approx.5.4 nT). A decomposition of the solar wind into high-speed streams, slow solar wind, and coronal mass ejections (CMEs; including postshock flows) reveals that the Sun transmits its message of changing magnetic field (diffusion coefficient) to the heliosphere primarily through CMEs at solar maximum and high-speed streams at solar minimum. Long-term reconstructions of solar wind B are in general agreement for the approx. 1900-present interval and can be used to reliably estimate GCR intensity over this period. For earlier epochs, however, a recent Be-10-based reconstruction covering the past approx. 10(exp 4) years shows nine abrupt and relatively short-lived drops of B to < or approx.= 0 nT, with the first of these corresponding to the Sporer minimum. Such dips are at variance with the recent suggestion that B has a minimum or floor value of approx.2.8 nT. A floor in solar wind B implies a ceiling in the GCR intensity (a permanent modulation of the local interstellar spectrum) at a given energy/rigidity. The 30-40% increase in the intensity of 2.5 GV electrons observed by Ulysses during the recent solar minimum raises an interesting paradox that will need to be resolved.

  5. Linear Covariance Analysis and Epoch State Estimators

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis; Carpenter, J. Russell

    2014-01-01

    This paper extends in two directions the results of prior work on generalized linear covariance analysis of both batch least-squares and sequential estimators. The first is an improved treatment of process noise in the batch, or epoch state, estimator with an epoch time that may be later than some or all of the measurements in the batch. The second is to account for process noise in specifying the gains in the epoch state estimator. We establish the conditions under which the latter estimator is equivalent to the Kalman filter.

  6. Linear Covariance Analysis and Epoch State Estimators

    NASA Technical Reports Server (NTRS)

    Markley, F. Landis; Carpenter, J. Russell

    2012-01-01

    This paper extends in two directions the results of prior work on generalized linear covariance analysis of both batch least-squares and sequential estimators. The first is an improved treatment of process noise in the batch, or epoch state, estimator with an epoch time that may be later than some or all of the measurements in the batch. The second is to account for process noise in specifying the gains in the epoch state estimator. We establish the conditions under which the latter estimator is equivalent to the Kalman filter.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Borovsky, Joseph E; Cayton, Thomas E; Denton, Michael H

    Electron flux measurements from 7 satellites in geosynchronous orbit from 1990-2007 are fit with relativistic bi-Maxwellians, yielding a number density n and temperature T description of the outer electron radiation belt. For 54.5 spacecraft years of measurements the median value ofn is 3.7x10-4 cm-3 and the median value ofT is 142 keY. General statistical properties of n, T, and the 1.1-1.5 MeV flux J are investigated, including local-time and solar-cycle dependencies. Using superposed-epoch analysis triggered on storm onset, the evolution of the outer electron radiation belt through high-speed-steam-driven storms is investigated. The number density decay during the calm before themore » storm is seen, relativistic-electron dropouts and recoveries from dropout are investigated, and the heating of the outer electron radiation belt during storms is examined. Using four different triggers (SSCs, southward-IMF CME sheaths, southward-IMF magnetic clouds, and minimum Dst), CME-driven storms are analyzed with superposed-epoch techniques. For CME-driven storms an absence of a density decay prior to storm onset is found, the compression of the outer electron radiation belt at time of SSC is analyzed, the number-density increase and temperature decrease during storm main phase is seen, and the increase in density and temperature during storm recovery phase is observed. Differences are found between the density-temperature and the flux descriptions, with more information for analysis being available in the density-temperature description.« less

  8. Automatic sleep stage classification using two-channel electro-oculography.

    PubMed

    Virkkala, Jussi; Hasan, Joel; Värri, Alpo; Himanen, Sari-Leena; Müller, Kiti

    2007-10-15

    An automatic method for the classification of wakefulness and sleep stages SREM, S1, S2 and SWS was developed based on our two previous studies. The method is based on a two-channel electro-oculography (EOG) referenced to the left mastoid (M1). Synchronous electroencephalographic (EEG) activity in S2 and SWS was detected by calculating cross-correlation and peak-to-peak amplitude difference in the 0.5-6 Hz band between the two EOG channels. An automatic slow eye-movement (SEM) estimation was used to indicate wakefulness, SREM and S1. Beta power 18-30 Hz and alpha power 8-12 Hz was also used for wakefulness detection. Synchronous 1.5-6 Hz EEG activity and absence of large eye movements was used for S1 separation from SREM. Simple smoothing rules were also applied. Sleep EEG, EOG and EMG were recorded from 265 subjects. The system was tuned using data from 132 training subjects and then applied to data from 131 validation subjects that were different to the training subjects. Cohen's Kappa between the visual and the developed new automatic scoring in separating 30s wakefulness, SREM, S1, S2 and SWS epochs was substantial 0.62 with epoch by epoch agreement of 72%. With automatic subject specific alpha thresholds for offline applications results improved to 0.63 and 73%. The automatic method can be further developed and applied for ambulatory sleep recordings by using only four disposable, self-adhesive and self-applicable electrodes.

  9. OT2_smalhotr_3: Herschel Extreme Lensing Line Observations (HELLO)

    NASA Astrophysics Data System (ADS)

    Malhotra, S.

    2011-09-01

    We request 59.8 hours of Herschel time to observe 20 normal star-forming galaxies in the [CII] 158 micron and [OI] 63 micron lines. These galaxies lie at high redshift (1

  10. EEG epochs with less alpha rhythm improve discrimination of mild Alzheimer's.

    PubMed

    Kanda, Paulo A M; Oliveira, Eliezyer F; Fraga, Francisco J

    2017-01-01

    Eyes-closed-awake electroencephalogram (EEG) is a useful tool in the diagnosis of Alzheimer's. However, there is eyes-closed-awake EEG with dominant or rare alpha rhythm. In this paper, we show that random selection of EEG epochs disregarding the alpha rhythm will lead to bias concerning EEG-based Alzheimer's Disease diagnosis. We compared EEG epochs with more than 30% and with less than 30% alpha rhythm of mild Alzheimer's Disease patients and healthy elderly. We classified epochs as dominant alpha scenario and rare alpha scenario according to alpha rhythm (8-13 Hz) percentage in O1, O2 and Oz channels. Accordingly, we divided the probands into four groups: 17 dominant alpha scenario controls, 15 mild Alzheimer's patients with dominant alpha scenario epochs, 12 rare alpha scenario healthy elderly and 15 mild Alzheimer's Disease patients with rare alpha scenario epochs. We looked for group differences using one-way ANOVA tests followed by post-hoc multiple comparisons (p < 0.05) over normalized energy values (%) on the other four well-known frequency bands (delta, theta, beta and gamma) using two different electrode configurations (parieto-occipital and central). After carrying out post-hoc multiple comparisons, for both electrode configurations we found significant differences between mild Alzheimer's patients and healthy elderly on beta- and theta-energy (%) only for the rare alpha scenario. No differences were found for the dominant alpha scenario in any of the five frequency bands. This is the first study of Alzheimer's awake-EEG reporting the influence of alpha rhythm on epoch selection, where our results revealed that, contrarily to what was most likely expected, less synchronized EEG epochs (rare alpha scenario) better discriminated mild Alzheimer's than those presenting abundant alpha (dominant alpha scenario). In addition, we find out that epoch selection is a very sensitive issue in qEEG research. Consequently, for Alzheimer's studies dealing with resting state EEG, we propose that epoch selection strategies should always be cautiously designed and thoroughly explained. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  11. Survival and Neurodevelopmental Outcomes among Periviable Infants.

    PubMed

    Younge, Noelle; Goldstein, Ricki F; Bann, Carla M; Hintz, Susan R; Patel, Ravi M; Smith, P Brian; Bell, Edward F; Rysavy, Matthew A; Duncan, Andrea F; Vohr, Betty R; Das, Abhik; Goldberg, Ronald N; Higgins, Rosemary D; Cotten, C Michael

    2017-02-16

    Data reported during the past 5 years indicate that rates of survival have increased among infants born at the borderline of viability, but less is known about how increased rates of survival among these infants relate to early childhood neurodevelopmental outcomes. We compared survival and neurodevelopmental outcomes among infants born at 22 to 24 weeks of gestation, as assessed at 18 to 22 months of corrected age, across three consecutive birth-year epochs (2000-2003 [epoch 1], 2004-2007 [epoch 2], and 2008-2011 [epoch 3]). The infants were born at 11 centers that participated in the National Institute of Child Health and Human Development Neonatal Research Network. The primary outcome measure was a three-level outcome - survival without neurodevelopmental impairment, survival with neurodevelopmental impairment, or death. After accounting for differences in infant characteristics, including birth center, we used multinomial generalized logit models to compare the relative risk of survival without neurodevelopmental impairment, survival with neurodevelopmental impairment, and death. Data on the primary outcome were available for 4274 of 4458 infants (96%) born at the 11 centers. The percentage of infants who survived increased from 30% (424 of 1391 infants) in epoch 1 to 36% (487 of 1348 infants) in epoch 3 (P<0.001). The percentage of infants who survived without neurodevelopmental impairment increased from 16% (217 of 1391) in epoch 1 to 20% (276 of 1348) in epoch 3 (P=0.001), whereas the percentage of infants who survived with neurodevelopmental impairment did not change significantly (15% [207 of 1391] in epoch 1 and 16% [211 of 1348] in epoch 3, P=0.29). After adjustment for changes in the baseline characteristics of the infants over time, both the rate of survival with neurodevelopmental impairment (as compared with death) and the rate of survival without neurodevelopmental impairment (as compared with death) increased over time (adjusted relative risks, 1.27 [95% confidence interval {CI}, 1.01 to 1.59] and 1.59 [95% CI, 1.28 to 1.99], respectively). The rate of survival without neurodevelopmental impairment increased between 2000 and 2011 in this large cohort of periviable infants. (Funded by the National Institutes of Health and others; ClinicalTrials.gov numbers, NCT00063063 and NCT00009633 .).

  12. Brain network segregation and integration during an epoch-related working memory fMRI experiment.

    PubMed

    Fransson, Peter; Schiffler, Björn C; Thompson, William Hedley

    2018-05-17

    The characterization of brain subnetwork segregation and integration has previously focused on changes that are detectable at the level of entire sessions or epochs of imaging data. In this study, we applied time-varying functional connectivity analysis together with temporal network theory to calculate point-by-point estimates in subnetwork segregation and integration during an epoch-based (2-back, 0-back, baseline) working memory fMRI experiment as well as during resting-state. This approach allowed us to follow task-related changes in subnetwork segregation and integration at a high temporal resolution. At a global level, the cognitively more taxing 2-back epochs elicited an overall stronger response of integration between subnetworks compared to the 0-back epochs. Moreover, the visual, sensorimotor and fronto-parietal subnetworks displayed characteristic and distinct temporal profiles of segregation and integration during the 0- and 2-back epochs. During the interspersed epochs of baseline, several subnetworks, including the visual, fronto-parietal, cingulo-opercular and dorsal attention subnetworks showed pronounced increases in segregation. Using a drift diffusion model we show that the response time for the 2-back trials are correlated with integration for the fronto-parietal subnetwork and correlated with segregation for the visual subnetwork. Our results elucidate the fast-evolving events with regard to subnetwork integration and segregation that occur in an epoch-related task fMRI experiment. Our findings suggest that minute changes in subnetwork integration are of importance for task performance. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  13. Faint Object Detection in Multi-Epoch Observations via Catalog Data Fusion

    NASA Astrophysics Data System (ADS)

    Budavári, Tamás; Szalay, Alexander S.; Loredo, Thomas J.

    2017-03-01

    Astronomy in the time-domain era faces several new challenges. One of them is the efficient use of observations obtained at multiple epochs. The work presented here addresses faint object detection and describes an incremental strategy for separating real objects from artifacts in ongoing surveys. The idea is to produce low-threshold single-epoch catalogs and to accumulate information across epochs. This is in contrast to more conventional strategies based on co-added or stacked images. We adopt a Bayesian approach, addressing object detection by calculating the marginal likelihoods for hypotheses asserting that there is no object or one object in a small image patch containing at most one cataloged source at each epoch. The object-present hypothesis interprets the sources in a patch at different epochs as arising from a genuine object; the no-object hypothesis interprets candidate sources as spurious, arising from noise peaks. We study the detection probability for constant-flux objects in a Gaussian noise setting, comparing results based on single and stacked exposures to results based on a series of single-epoch catalog summaries. Our procedure amounts to generalized cross-matching: it is the product of a factor accounting for the matching of the estimated fluxes of the candidate sources and a factor accounting for the matching of their estimated directions. We find that probabilistic fusion of multi-epoch catalogs can detect sources with similar sensitivity and selectivity compared to stacking. The probabilistic cross-matching framework underlying our approach plays an important role in maintaining detection sensitivity and points toward generalizations that could accommodate variability and complex object structure.

  14. Electron heating and Tp/Te variations during magnetic dipolarizations

    NASA Astrophysics Data System (ADS)

    Grigorenko, Elena; Kronberg, Elena; Daly, Patrick; Ganushkina, Natalia; Lavraud, Benoit; Sauvaud, Jean-Andre; Zelenyi, Lev

    2017-04-01

    The proton-to-electron temperature ratio (Tp/Te) in the plasma sheet (PS) of the Earth's magnetotail is studied by using 5 years of Cluster observations (2001-2005). The PS intervals are searched within a region defined with -19

  15. Inactivation of basolateral amygdala specifically eliminates palatability-related information in cortical sensory responses.

    PubMed

    Piette, Caitlin E; Baez-Santiago, Madelyn A; Reid, Emily E; Katz, Donald B; Moran, Anan

    2012-07-18

    Evidence indirectly implicates the amygdala as the primary processor of emotional information used by cortex to drive appropriate behavioral responses to stimuli. Taste provides an ideal system with which to test this hypothesis directly, as neurons in both basolateral amygdala (BLA) and gustatory cortex (GC)-anatomically interconnected nodes of the gustatory system-code the emotional valence of taste stimuli (i.e., palatability), in firing rate responses that progress similarly through "epochs." The fact that palatability-related firing appears one epoch earlier in BLA than GC is broadly consistent with the hypothesis that such information may propagate from the former to the latter. Here, we provide evidence supporting this hypothesis, assaying taste responses in small GC single-neuron ensembles before, during, and after temporarily inactivating BLA in awake rats. BLA inactivation (BLAx) changed responses in 98% of taste-responsive GC neurons, altering the entirety of every taste response in many neurons. Most changes involved reductions in firing rate, but regardless of the direction of change, the effect of BLAx was epoch-specific: while firing rates were changed, the taste specificity of responses remained stable; information about taste palatability, however, which normally resides in the "Late" epoch, was reduced in magnitude across the entire GC sample and outright eliminated in most neurons. Only in the specific minority of neurons for which BLAx enhanced responses did palatability specificity survive undiminished. Our data therefore provide direct evidence that BLA is a necessary component of GC gustatory processing, and that cortical palatability processing in particular is, in part, a function of BLA activity.

  16. Inactivation of basolateral amygdala specifically eliminates palatability-related information in cortical sensory responses

    PubMed Central

    Piette, Caitlin E.; Baez-Santiago, Madelyn A.; Reid, Emily E.; Katz, Donald B.; Moran, Anan

    2012-01-01

    Evidence indirectly implicates the amygdala as the primary processor of emotional information used by cortex to drive appropriate behavioral responses to stimuli. Taste provides an ideal system with which to test this hypothesis directly, as neurons in both basolateral amygdala (BLA) and gustatory cortex (GC)—anatomically interconnected nodes of the gustatory system—code the emotional valence of taste stimuli (i.e., palatability), in firing rate responses that progress similarly through “epochs.” The fact that palatability-related firing appears one epoch earlier in BLA than GC is broadly consistent with the hypothesis that such information may propagate from the former to the latter. Here, we provide evidence supporting this hypothesis, assaying taste responses in small GC single-neuron ensembles before, during and after temporarily inactivating BLA (BLAx) in awake rats. BLAx changed responses in 98% of taste-responsive GC neurons, altering the entirety of every taste response in many neurons. Most changes involved reductions in firing rate, but regardless of the direction of change, the effect of BLAx was epoch-specific: while firing rates were changed, the taste-specificity of responses remained stable; information about taste palatability, however, which normally resides in the “Late” epoch, was reduced in magnitude across the entire GC sample and outright eliminated in most neurons. Only in the specific minority of neurons for which BLAx enhanced responses did palatability-specificity survive undiminished. Our data therefore provide direct evidence that BLA is a necessary component of GC gustatory processing, and that cortical palatability processing in particular is, in part, a function of BLA activity. PMID:22815512

  17. Different Simultaneous Sleep States in the Hippocampus and Neocortex.

    PubMed

    Emrick, Joshua J; Gross, Brooks A; Riley, Brett T; Poe, Gina R

    2016-12-01

    Investigators assign sleep-waking states using brain activity collected from a single site, with the assumption that states occur at the same time throughout the brain. We sought to determine if sleep-waking states differ between two separate structures: the hippocampus and neocortex. We measured electrical signals (electroencephalograms and electromyograms) during sleep from the hippocampus and neocortex of five freely behaving adult male rats. We assigned sleep-waking states in 10-sec epochs based on standard scoring criteria across a 4-h recording, then analyzed and compared states and signals from simultaneous epochs between sites. We found that the total amount of each state, assigned independently using the hippocampal and neocortical signals, was similar between the hippocampus and neocortex. However, states at simultaneous epochs were different as often as they were the same (P = 0.82). Furthermore, we found that the progression of states often flowed through asynchronous state-pairs led by the hippocampus. For example, the hippocampus progressed from transition-to-rapid eye movement sleep to rapid eye movement sleep before the neocortex more often than in synchrony with the neocortex (38.7 ± 16.2% versus 15.8 ± 5.6% mean ± standard error of the mean). We demonstrate that hippocampal and neocortical sleep-waking states often differ in the same epoch. Consequently, electrode location affects estimates of sleep architecture, state transition timing, and perhaps even percentage of time in sleep states. Therefore, under normal conditions, models assuming brain state homogeneity should not be applied to the sleeping or waking brain. © 2016 Associated Professional Sleep Societies, LLC.

  18. The Anthropo-scene: A guide for the perplexed.

    PubMed

    Lorimer, Jamie

    2017-02-01

    The scientific proposal that the Earth has entered a new epoch as a result of human activities - the Anthropocene - has catalysed a flurry of intellectual activity. I introduce and review the rich, inchoate and multi-disciplinary diversity of this Anthropo-scene. I identify five ways in which the concept of the Anthropocene has been mobilized: scientific question, intellectual zeitgeist, ideological provocation, new ontologies and science fiction. This typology offers an analytical framework for parsing this diversity, for understanding the interactions between different ways of thinking in the Anthropo-scene, and thus for comprehending elements of its particular and peculiar sociabilities. Here I deploy this framework to situate Earth Systems Science within the Anthropo-scene, exploring both the status afforded science in discussions of this new epoch, and the various ways in which the other means of engaging with the concept come to shape the conduct, content and politics of this scientific enquiry. In conclusion the paper reflects on the potential of the Anthropocene for new modes of academic praxis.

  19. Does resting-state connectivity reflect depressive rumination? A tale of two analyses.

    PubMed

    Berman, Marc G; Misic, Bratislav; Buschkuehl, Martin; Kross, Ethan; Deldin, Patricia J; Peltier, Scott; Churchill, Nathan W; Jaeggi, Susanne M; Vakorin, Vasily; McIntosh, Anthony R; Jonides, John

    2014-12-01

    Major Depressive Disorder (MDD) is characterized by rumination. Prior research suggests that resting-state brain activation reflects rumination when depressed individuals are not task engaged. However, no study has directly tested this. Here we investigated whether resting-state epochs differ from induced ruminative states for healthy and depressed individuals. Most previous research on resting-state networks comes from seed-based analyses with the posterior cingulate cortex (PCC). By contrast, we examined resting state connectivity by using the complete multivariate connectivity profile (i.e., connections across all brain nodes) and by comparing these results to seeded analyses. We find that unconstrained resting-state intervals differ from active rumination states in strength of connectivity and that overall connectivity was higher for healthy vs. depressed individuals. Relationships between connectivity and subjective mood (i.e., behavior) were strongly observed during induced rumination epochs. Furthermore, connectivity patterns that related to subjective mood were strikingly different for MDD and healthy control (HC) groups suggesting different mood regulation mechanisms. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Formation and mantling ages of lobate debris aprons on Mars: Insights from categorized crater counts

    NASA Astrophysics Data System (ADS)

    Berman, Daniel C.; Crown, David A.; Joseph, Emily C. S.

    2015-06-01

    Lobate debris aprons in the Martian mid-latitudes offer important insights into the history of the Martian climate and the role of volatiles in Martian geologic activity. Here we present the results of counts of small impact craters, categorized by morphology, on debris aprons in the Deuteronilus Mensae region and the area east of Hellas basin. Mars Reconnaissance Orbiter (MRO) ConTeXt Camera (CTX) images were used to document crater populations on the apron surfaces. Each crater was assessed and categorized according to its morphological characteristics (fresh, degraded, or filled). Fresh and most degraded craters likely superpose recent mantling deposits, whereas filled craters contain mantling deposits and thus indicate a minimum formation age for the apron (i.e., the age since stabilization of the debris apron surface following some modification but prior to mantling). Size-frequency distributions (SFDs) were compiled using established methodologies and plotted to assess their fit to the isochrons. The range or ranges in crater diameter over which each distribution paralleled the isochrons was determined by visual inspection, and general age constraints were noted from SFDs for all craters on a given surface and from each morphological class. The diameter range of each SFD segment observed to parallel an isochron was then input into the Craterstats2 analysis tool to calculate specific age estimates. The aprons were assessed both individually and as regional populations, which improved interpretation of the results and demonstrated the value and limitations of both approaches. The categorized counts reveal three groups of ages: (a) filled impact craters at larger diameters (>~500 m) typically show the oldest ages, between ~300 Ma and 1 Ga, (b) smaller diameter filled and degraded craters reveal ages of resurfacing events between ~10 Ma and 300 Ma, and (c) fresh crater populations (<~100 m diameter) indicate mantling deposits of less than ~10 Ma in age. These results indicate that the lobate debris apron populations formed (or their surfaces became stable) in the Early to Middle Amazonian Epochs, and were subsequently subjected to complex degradation by erosion and sublimation and/or melting of contained ice, culminating in episodes of deposition of ice-rich mantles in the Late Amazonian Epoch.

  1. The Universe Adventure - The Plank Epoch

    Science.gov Websites

    Physics In the time before the first 10-44 seconds of the Universe, or the Planck Epoch, the laws of physics as we know them break down; the predictions of General Relativity become meaningless as distance physics models predict that during this epoch the four fundamental forces were combined into one unified

  2. Faint Object Detection in Multi-Epoch Observations via Catalog Data Fusion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Budavári, Tamás; Szalay, Alexander S.; Loredo, Thomas J.

    Astronomy in the time-domain era faces several new challenges. One of them is the efficient use of observations obtained at multiple epochs. The work presented here addresses faint object detection and describes an incremental strategy for separating real objects from artifacts in ongoing surveys. The idea is to produce low-threshold single-epoch catalogs and to accumulate information across epochs. This is in contrast to more conventional strategies based on co-added or stacked images. We adopt a Bayesian approach, addressing object detection by calculating the marginal likelihoods for hypotheses asserting that there is no object or one object in a small imagemore » patch containing at most one cataloged source at each epoch. The object-present hypothesis interprets the sources in a patch at different epochs as arising from a genuine object; the no-object hypothesis interprets candidate sources as spurious, arising from noise peaks. We study the detection probability for constant-flux objects in a Gaussian noise setting, comparing results based on single and stacked exposures to results based on a series of single-epoch catalog summaries. Our procedure amounts to generalized cross-matching: it is the product of a factor accounting for the matching of the estimated fluxes of the candidate sources and a factor accounting for the matching of their estimated directions. We find that probabilistic fusion of multi-epoch catalogs can detect sources with similar sensitivity and selectivity compared to stacking. The probabilistic cross-matching framework underlying our approach plays an important role in maintaining detection sensitivity and points toward generalizations that could accommodate variability and complex object structure.« less

  3. Was the Sun especially active at the end of the late glacial epoch?

    NASA Astrophysics Data System (ADS)

    Alekseeva, Liliya

    In their pioneering work, the geophysicists A. Brekke and A. Egeland (1983) collected beliefs of different peoples, associated with northern lights. Our analyses of this collection show that these beliefs are mainly related to the mythological idea of ``abnormal'' deads (dead, childless old maids in Finnish beliefs; killed people; spirits dangerous to children). We find similar motifs in Slavic fairy tales about the ``Thrice-Nine Land,'' regarded as the other world in folkloric studies (in the Land where mobile and agitated warlike girls live, whose Head Girl is characterized by the words ``white snow, pretty light, the prettiest in the World,'' but whose name ``Mariya Morevna'' refers to the word ``mort''; where a river flows with its banks covered by human bones; where the witch Baba-Yaga dwells, being extremely dangerous for children). Moreover, it can be noted that similar narrative fabulous myths deal with the concept of auroral oval northern lights, since some specific features of the natural auroral forms are mentioned there, with their particular spatial orientations (to the North or West). This resembles the manner in which Ancient Greek myths describe the real properties of the heavenly phenomena in a mythological language. It is interesting that myths on the high-latitude northern lights spread even to the South of Europe (and, might be, to India and Iran). This fact can be understood in view of the following. It has been established that, during the late glacial epoch, the environmental and cultural conditions were similar over the area from Pyrenean to the Ural Mountains; the pattern of hunters' settlements outlined the glacial sheet from the outside. Relics of the hunters' beliefs can now be found in Arctic, where the environment and lifestyle remain nearly unchanged. The ethnographer Yu.B. Simchenko (1976) has reconstructed the most archaic Arctic myths. According to them, the World of dead is associated with the world of ice governed by the ``Ice mother,'' who takes human souls to the World of dead. At the beginning of glacial-sheet degradation, people lived by hunting for wild reindeer. The animal moved to high latitudes behind the edge of the thawing glacial sheet, and the people followed the main object of their hunting. Thus, they went in the direction of their mythological World of dead. As they unexpectedly discovered the enchanting eye-catcher of northern lights, they should assume that they encountered the border of the World of dead. Emotional experience gained from such direct contact with the World of dead, as also from the narratives about the fascinating and spectacular view of this World seen by their own eyes, was recorded in the cosmological myths. Later, the descendants of the hunters scattered over the drying earth, which rapidly became overgrown with forest. The relics of their cosmological myths persist as a cultural phenomenon. Thus, the cultural inheritance looks like evidence of high auroral and solar activity at the epoch when the glacial sheet was thawing. If so, we deal with a mirror reflection of the correlation between the space weather and climate known for Maunder's minimum.

  4. Neutrino probe comparisons of supernovae as a function of redshift

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fryer, Christopher Lee

    2009-01-01

    We compare aspects of supernova explosions produced in the current epoch against those produced in the first round of star formation. Although the total final mass of stars can change dramatically between these two epochs due to different mass-loss rates from winds, their cores remam very similar. The core structure is more sensitive to the stellar evolution code than it is to the amount of metals. As such, current stellar models produce supernovae from first stars that look very similar to that of stars produced in the current epoch. The neutrino signal, a powerful probe of the inner core, ismore » identical to the few percent level for both star formation epochs. A change in the neutrino signal in the supernova population between these two star formation epochs will only arise if the initial mass function is altered.« less

  5. Joint Estimation of the Epoch of Reionization Power Spectrum and Foregrounds

    NASA Astrophysics Data System (ADS)

    Sims, Peter; Pober, Jonathan

    2018-01-01

    Bright astrophysical foregrounds present a significant impediment to the detection of redshifted 21-cm emission from the Epoch of Reionization on large spatial scales. In this talk I present a framework for the joint modeling of the power spectral contamination by astrophysical foregrounds and the power spectrum of the Epoch of Reionization. I show how informative priors on the power spectral contamination by astrophysical foregrounds at high redshifts, where emission from both the Epoch of Reionization and its foregrounds is present in the data, can be obtained through analysis of foreground-only emission at lower redshifts. Finally, I demonstrate how, by using such informative foreground priors, joint modeling can be employed to mitigate bias in estimates of the power spectrum of the Epoch of Reionization signal and, in particular, to enable recovery of more robust power spectral estimates on large spatial scales.

  6. Expressions for the precession quantities based upon the IAU /1976/ system of astronomical constants

    NASA Technical Reports Server (NTRS)

    Lieske, J. H.; Lederle, T.; Fricke, W.; Morando, B.

    1977-01-01

    The structure of the expressions usually employed in calculating the effects of precession is examined, and a method is outlined for revising the expressions to account for changes in the fundamental astronomical constants. It is shown that the basic set of parameters, upon which depend the lengthy polynomials for computing the mean obliquity of data and the elements of the precession matrix, consists of the mean obliquity, the speed of general precession in longitude at a fixed epoch, and the system of planetary masses. Special attention is given to the motion of the ecliptic pole, formulations for a basic epoch as well as an arbitrary epoch, and ecliptic motion relative to the basic epoch. Numerical precession quantities at epoch J2000.0 (JED 2451545.0) are presented which result from the revision of astronomical constants adopted at the XVI General Assembly of the IAU.

  7. The eclipse of Epsilon Aurigae visible spectroscopy and ultraviolet activity

    NASA Technical Reports Server (NTRS)

    Ferluga, S.; Hack, M.

    1985-01-01

    The preliminary results of the study of several high resolution spectrograms (lambda 3500 - lambda 7000 A), obtained at the Haute Provence Observatory (OHP) in France, at different epochs before, during and after the eclipse are reported. Some of these spectrograms are compared with corresponding IUE high resolution observations, in order to study the effects of the intrinsic UV activity, towards the longer wavelengths.

  8. The Effect of "Rogue" Active Regions on the Solar Cycle

    NASA Astrophysics Data System (ADS)

    Nagy, Melinda; Lemerle, Alexandre; Labonville, François; Petrovay, Kristóf; Charbonneau, Paul

    2017-11-01

    The origin of cycle-to-cycle variations in solar activity is currently the focus of much interest. It has recently been pointed out that large individual active regions with atypical properties can have a significant impact on the long-term behavior of solar activity. We investigate this possibility in more detail using a recently developed 2×2D dynamo model of the solar magnetic cycle. We find that even a single "rogue" bipolar magnetic region (BMR) in the simulations can have a major effect on the further development of solar activity cycles, boosting or suppressing the amplitude of subsequent cycles. In extreme cases, an individual BMR can completely halt the dynamo, triggering a grand minimum. Rogue BMRs also have the potential to induce significant hemispheric asymmetries in the solar cycle. To study the effect of rogue BMRs in a more systematic manner, a series of dynamo simulations were conducted, in which a large test BMR was manually introduced in the model at various phases of cycles of different amplitudes. BMRs emerging in the rising phase of a cycle can modify the amplitude of the ongoing cycle, while BMRs emerging in later phases will only affect subsequent cycles. In this model, the strongest effect on the subsequent cycle occurs when the rogue BMR emerges around cycle maximum at low latitudes, but the BMR does not need to be strictly cross-equatorial. Active regions emerging as far as 20° from the equator can still have a significant effect. We demonstrate that the combined effect of the magnetic flux, tilt angle, and polarity separation of the BMR on the dynamo is via their contribution to the dipole moment, δ D_{BMR}. Our results indicate that prediction of the amplitude, starting epoch, and duration of a cycle requires an accurate accounting of a broad range of active regions emerging in the previous cycle.

  9. Epoch Lifetimes in the Dynamics of a Competing Population

    NASA Astrophysics Data System (ADS)

    Yeung, C. H.; Ma, Y. P.; Wong, K. Y. Michael

    We propose a dynamical model of a competing population whose agents have a tendency to balance their decisions in time. The model is applicable to financial markets in which the agents trade with finite capital, or other multiagent systems such as routers in communication networks attempting to transmit multiclass traffic in a fair way. We find an oscillatory behavior due to the segregation of agents into two groups. Each group remains winning over epochs. The aggregation of smart agents is able to explain the lifetime distribution of epochs to 8 decades of probability. The existence of the super agents further refines the lifetime distribution of short epochs.

  10. EPOCH regimen as salvage therapy for adult T-cell leukemia-lymphoma.

    PubMed

    Toriyama, Eo; Imaizumi, Yoshitaka; Taniguchi, Hiroaki; Taguchi, Jun; Nakashima, Jun; Itonaga, Hidehiro; Sato, Shinya; Ando, Koji; Sawayama, Yasushi; Hata, Tomoko; Fukushima, Takuya; Miyazaki, Yasushi

    2018-04-12

    Adult T-cell leukemia-lymphoma (ATL) is an intractable hematopoietic malignancy with a very poor prognosis. Although improved responses have been achieved through intensive chemotherapy in newly diagnosed patients with aggressive ATL, most patients suffer from relapse or disease recurrence, and an effective salvage therapy, especially for candidates for allogeneic hematopoietic stem cell transplantation (allo-HSCT), is yet to be established. The efficacy of the EPOCH regimen has been reported for several lymphoid malignancies; however, its efficacy for ATL has not been sufficiently evaluated. Here, we report results of a study of the EPOCH regimen as a salvage therapy for ATL. We retrospectively analyzed patients with relapsed or refractory ATL treated in our institution, with EPOCH as a first salvage therapy. Fourteen patients with a median age of 58 years were analyzed, among whom eight achieved a response, including a complete response in one patient and partial responses in seven. Seven patients underwent allo-HSCT after EPOCH therapy; however, the median overall survival (OS) could not be determined, whereas OS at 2 years after allo-HSCT was estimated to be 85.7%. These results suggest that EPOCH is an option for salvage therapy in patients with ATL, including candidates for allo-HSCT.

  11. Survival and Neurodevelopmental Outcomes among Periviable Infants

    PubMed Central

    Younge, Noelle; Goldstein, Ricki F.; Bann, Carla M.; Hintz, Susan R.; Patel, Ravi M.; Smith, P. Brian; Bell, Edward F.; Rysavy, Matthew A.; Duncan, Andrea F.; Vohr, Betty R.; Das, Abhik; Goldberg, Ronald N.; Higgins, Rosemary D.; Cotten, C. Michael

    2017-01-01

    BACKGROUND Data reported during the past 5 years indicate that rates of survival have increased among infants born at the borderline of viability, but less is known about how increased rates of survival among these infants relate to early childhood neurodevelopmental outcomes. METHODS We compared survival and neurodevelopmental outcomes among infants born at 22 to 24 weeks of gestation, as assessed at 18 to 22 months of corrected age, across three consecutive birth-year epochs (2000–2003 [epoch 1], 2004–2007 [epoch 2], and 2008–2011 [epoch 3]). The infants were born at 11 centers that participated in the National Institute of Child Health and Human Development Neonatal Research Network. The primary outcome measure was a three-level outcome — survival without neurodevelopmental impairment, survival with neurodevelopmental impairment, or death. After accounting for differences in infant characteristics, including birth center, we used multinomial generalized logit models to compare the relative risk of survival without neurodevelopmental impairment, survival with neurodevelopmental impairment, and death. RESULTS Data on the primary outcome were available for 4274 of 4458 infants (96%) born at the 11 centers. The percentage of infants who survived increased from 30% (424 of 1391 infants) in epoch 1 to 36% (487 of 1348 infants) in epoch 3 (P<0.001). The percentage of infants who survived without neurodevelopmental impairment increased from 16% (217 of 1391) in epoch 1 to 20% (276 of 1348) in epoch 3 (P = 0.001), whereas the percentage of infants who survived with neurodevelopmental impairment did not change significantly (15% [207 of 1391] in epoch 1 and 16% [211 of 1348] in epoch 3, P = 0.29). After adjustment for changes in the baseline characteristics of the infants over time, both the rate of survival with neurodevelopmental impairment (as compared with death) and the rate of survival without neurodevelopmental impairment (as compared with death) increased over time (adjusted relative risks, 1.27 [95% confidence interval {CI}, 1.01 to 1.59] and 1.59 [95% CI, 1.28 to 1.99], respectively). CONCLUSIONS The rate of survival without neurodevelopmental impairment increased between 2000 and 2011 in this large cohort of periviable infants. (Funded by the National Institutes of Health and others; ClinicalTrials.gov numbers, NCT00063063 and NCT00009633.) PMID:28199816

  12. [Prof. Francis Albert Eley Crew - the great friend of Poles from the past epoch].

    PubMed

    Midro, A

    1995-01-01

    In the article there is presented a figure of prof. D.A. Crew - English scientist doctor (physician) and geneticist, who during the IInd world War was involved in organisation and activity of Polish Faculty of Medicine University of Edinburgh. The attention has been drawn to the motives, which induced prof. F.A. Crew to take up the medical studies, the pre-war activity in Institute of Edinburgh and scientific activity of his team.

  13. Pre-School Teachers' Informatics and Information Literacy

    ERIC Educational Resources Information Center

    Tatkovic, Nevenka; Ruzic, Maja; Pecaric, Dilda

    2006-01-01

    The life and activities of every man in the period of transition from the second into the third millennium have been marked by epochal changes which appear as the consequence of scientific and technological revolution dominated by highly developed information and communication technology. Informatics and information education based on information…

  14. Toward the Probabilistic Forecasting of High-latitude GPS Phase Scintillation

    NASA Technical Reports Server (NTRS)

    Prikryl, P.; Jayachandran, P.T.; Mushini, S. C.; Richardson, I. G.

    2012-01-01

    The phase scintillation index was obtained from L1 GPS data collected with the Canadian High Arctic Ionospheric Network (CHAIN) during years of extended solar minimum 2008-2010. Phase scintillation occurs predominantly on the dayside in the cusp and in the nightside auroral oval. We set forth a probabilistic forecast method of phase scintillation in the cusp based on the arrival time of either solar wind corotating interaction regions (CIRs) or interplanetary coronal mass ejections (ICMEs). CIRs on the leading edge of high-speed streams (HSS) from coronal holes are known to cause recurrent geomagnetic and ionospheric disturbances that can be forecast one or several solar rotations in advance. Superposed epoch analysis of phase scintillation occurrence showed a sharp increase in scintillation occurrence just after the arrival of high-speed solar wind and a peak associated with weak to moderate CMEs during the solar minimum. Cumulative probability distribution functions for the phase scintillation occurrence in the cusp are obtained from statistical data for days before and after CIR and ICME arrivals. The probability curves are also specified for low and high (below and above median) values of various solar wind plasma parameters. The initial results are used to demonstrate a forecasting technique on two example periods of CIRs and ICMEs.

  15. Estimating Noise in the Hydrogen Epoch of Reionization Array

    NASA Astrophysics Data System (ADS)

    Englund Mathieu, Philip; HERA Team

    2017-01-01

    The Hydrogen Epoch of Reionization Array (HERA) is a radio telescope dedicated to observing large scale structure during and prior to the epoch of reionization. Once completed, HERA will have unprecedented sensitivity to the 21-cm signal from hydrogen reionization. This poster will present time- and frequency-subtraction methods and results from a preliminary analysis of the noise characteristics of the nineteen-element pathfinder array.

  16. Different Simultaneous Sleep States in the Hippocampus and Neocortex

    PubMed Central

    Emrick, Joshua J.; Gross, Brooks A.; Riley, Brett T.; Poe, Gina R.

    2016-01-01

    Study Objectives: Investigators assign sleep-waking states using brain activity collected from a single site, with the assumption that states occur at the same time throughout the brain. We sought to determine if sleep-waking states differ between two separate structures: the hippocampus and neocortex. Methods: We measured electrical signals (electroencephalograms and electromyograms) during sleep from the hippocampus and neocortex of five freely behaving adult male rats. We assigned sleep-waking states in 10-sec epochs based on standard scoring criteria across a 4-h recording, then analyzed and compared states and signals from simultaneous epochs between sites. Results: We found that the total amount of each state, assigned independently using the hippocampal and neocortical signals, was similar between the hippocampus and neocortex. However, states at simultaneous epochs were different as often as they were the same (P = 0.82). Furthermore, we found that the progression of states often flowed through asynchronous state-pairs led by the hippocampus. For example, the hippocampus progressed from transition-to-rapid eye movement sleep to rapid eye movement sleep before the neocortex more often than in synchrony with the neocortex (38.7 ± 16.2% versus 15.8 ± 5.6% mean ± standard error of the mean). Conclusions: We demonstrate that hippocampal and neocortical sleep-waking states often differ in the same epoch. Consequently, electrode location affects estimates of sleep architecture, state transition timing, and perhaps even percentage of time in sleep states. Therefore, under normal conditions, models assuming brain state homogeneity should not be applied to the sleeping or waking brain. Citation: Emrick JJ, Gross BA, Riley BT, Poe GR. Different simultaneous sleep states in the hippocampus and neocortex. SLEEP 2016;39(12):2201–2209. PMID:27748240

  17. Review of the Cambrian volcanic activity in Morocco: geochemical fingerprints and geotectonic implications for the rifting of West Gondwana

    NASA Astrophysics Data System (ADS)

    Pouclet, André; El Hadi, Hassan; Álvaro, J. Javier; Bardintzeff, Jacques-Marie; Benharref, Mohammed; Fekkak, Abdelilah

    2018-03-01

    Volcanic activities related to the opening of a Cambrian rift in Morocco were widespread from the Fortunian to the Cambrian Epoch 3. Numerous data are available from northwestern volcanic sites, particularly in the western High Atlas, but they are scarce from the southeastern sites. New data are documented here from the volcanic formations exposed in the Jbel Tazoult n'Ouzina of the Tafilalt Province, eastern Anti-Atlas and dated to Cambrian Epoch 2-3. The Cambrian volcanic activities recorded in the High Atlas, Anti-Atlas, and Coastal Meseta are synthesized to refine their stratigraphic setting and to characterize their magmatic affinities and fingerprints. Six volcanic pulses are determined as tholeiitic, transitional, and alkaline suites. The tholeiitic and transitional magmas originated from primitive mantle and E-MORB-type sources with a spinel- and garnet-bearing lherzolite composition. Some of them were modified by assimilation-fractional crystallisation processes during crust-mantle interactions. The alkaline magmas fit with an OIB-type and a garnet-bearing lherzolite source. The palaeogeographic distribution of the magmatic suites was controlled by the lithospheric thinning of the Cambrian Atlas Rift and lithospheric constraints of the Pan-African metacraton and West African craton.

  18. Period Variations in the Close Binary BM UMa

    NASA Astrophysics Data System (ADS)

    Virnina, Natalia A.; Panko, Elena; Sergienko, O. G.; Murnikov, Boris A.; Gubin, E. G.; Klabukova, A. V.; Movchan, A. I.

    2010-12-01

    We present the results of analysing of the light curve and O-C variations in the eclipsing system BM UMa, based on V-band observations which cover the period from JD 2454933 to 2454961 using two robotic remotely-controlled telescopes of Tzec Maun Observatory (USA) along with observations made with the RK-600 telescope of Odessa Astronomical Observatory. The full light curve displays a total primary eclipse with a duration 0.06 of the period, or 24 minutes, and a partial secondary eclipse, with both maxima of equal magnitude. For our obesrvations, we determined the statistically optimal values of the initial epoch of T0 = 2454944.2814 ± 0.0001 and orbital period of P = 0.d271226± 0.000002. The depths of primary and secondary minima are nearly equal, 0.m838 ± 0.006 and 0.m748 ± 0.006, respectively. The physical parameters of the system were calculated using the Wilson-Devinney code, appended with the Monte Carlo search algorithm. The result establishes BM UMa as a contact system (fillout factor 10.7%) with parameters: mass ratio 0.538 ± 0.001, inclination 86.°815 ± 0.005, and temperatures of components 4700 ± 20 K and 4510 ± 10 K. The more massive component is larger and cooler. The 72 archival and 11 newly-obtained times of light minimum cover the interval 1961-2010 and allowed us to exclude possible systematic period variations in BM UMa and to determine an initial epoch of HJD 2447927.382 and orbital period of P = 0.d2712209± 0.0000006.

  19. Functional recovery in upper limb function in stroke survivors by using brain-computer interface A single case A-B-A-B design.

    PubMed

    Ono, Takashi; Mukaino, Masahiko; Ushiba, Junichi

    2013-01-01

    Resent studies suggest that brain-computer interface (BCI) training for chronic stroke patient is useful to improve their motor function of paretic hand. However, these studies does not show the extent of the contribution of the BCI clearly because they prescribed BCI with other rehabilitation systems, e.g. an orthosis itself, a robotic intervention, or electrical stimulation. We therefore compared neurological effects between interventions with neuromuscular electrical stimulation (NMES) with motor imagery and BCI-driven NMES, employing an ABAB experimental design. In epoch A, the subject received NMES on paretic extensor digitorum communis (EDC). The subject was asked to attempt finger extension simultaneously. In epoch B, the subject received NMES when BCI system detected motor-related electroencephalogram change while attempting motor imagery. Both epochs were carried out for 60 min per day, 5 days per week. As a result, EMG activity of EDC was enhanced by BCI-driven NMES and significant cortico-muscular coherence was observed at the final evaluation. These results indicate that the training by BCI-driven NMES is effective even compared to motor imagery combined with NMES, suggesting the superiority of closed-loop training with BCI-driven NMES to open-loop NMES for chronic stroke patients.

  20. Magnetic substorms and northward IMF turning

    NASA Astrophysics Data System (ADS)

    Troshichev, Oleg; Podorozhkina, Nataly

    To determine the relation of the northward IMF turnings to substorm sudden onsets, we separated all events with sharp northward IMF turnings observed in years of solar maximum (1999-2002) and solar minimum (2007-2008). The events (N=261) have been classified in 5 groups in accordance with average magnetic activity in auroral zone (low, moderate or high levels of AL index) at unchanged or slightly changed PC index and with dynamics of PC (steady distinct growth or distinct decline) at arbitrary values of AL index. Statistical analysis of relationships between the IMF turning and changes of PC and AL indices has been fulfilled separately for each of 5 classes. Results of the analysis showed that, irrespective of geophysical conditions and solar activity epoch, the magnetic activity in the polar caps and in the auroral zone demonstrate no response to the sudden northward IMF turning, if the moment of northward turning is taken as a key date. Sharp increases of magnetic disturbance in the auroral zone are observed only under conditions of the growing PC index and statistically they are related to moment of the PC index exceeding the threshold level (~1.5 mV/m), not to northward turnings timed, as a rule, after the moment of sudden onset. Magnetic disturbances observed in these cases in the auroral zone (magnetic substorms) are guided by behavior of the PC index, like to ordinary magnetic substorms or substorms developed under conditions of the prolonged northward IMF impact on the magnetosphere. The evident inconsistency between the sharp IMF changes measured outside of the magnetosphere and behavior of the ground-based PC index, the latter determining the substorm development, provides an additional argument in favor of the PC index as a ground-based proxy of the solar wind energy that entered into magnetosphere.

  1. A detached stellar-mass black hole candidate in the globular cluster NGC 3201

    NASA Astrophysics Data System (ADS)

    Giesers, Benjamin; Dreizler, Stefan; Husser, Tim-Oliver; Kamann, Sebastian; Anglada Escudé, Guillem; Brinchmann, Jarle; Carollo, C. Marcella; Roth, Martin M.; Weilbacher, Peter M.; Wisotzki, Lutz

    2018-03-01

    As part of our massive spectroscopic survey of 25 Galactic globular clusters with MUSE, we performed multiple epoch observations of NGC 3201 with the aim of constraining the binary fraction. In this cluster, we found one curious star at the main-sequence turn-off with radial velocity variations of the order of 100 km s- 1, indicating the membership to a binary system with an unseen component since no other variations appear in the spectra. Using an adapted variant of the generalized Lomb-Scargle periodogram, we could calculate the orbital parameters and found the companion to be a detached stellar-mass black hole with a minimum mass of 4.36 ± 0.41 M⊙. The result is an important constraint for binary and black hole evolution models in globular clusters as well as in the context of gravitational wave sources.

  2. Dealing with Uncertainties in Initial Orbit Determination

    NASA Technical Reports Server (NTRS)

    Armellin, Roberto; Di Lizia, Pierluigi; Zanetti, Renato

    2015-01-01

    A method to deal with uncertainties in initial orbit determination (IOD) is presented. This is based on the use of Taylor differential algebra (DA) to nonlinearly map the observation uncertainties from the observation space to the state space. When a minimum set of observations is available DA is used to expand the solution of the IOD problem in Taylor series with respect to measurement errors. When more observations are available high order inversion tools are exploited to obtain full state pseudo-observations at a common epoch. The mean and covariance of these pseudo-observations are nonlinearly computed by evaluating the expectation of high order Taylor polynomials. Finally, a linear scheme is employed to update the current knowledge of the orbit. Angles-only observations are considered and simplified Keplerian dynamics adopted to ease the explanation. Three test cases of orbit determination of artificial satellites in different orbital regimes are presented to discuss the feature and performances of the proposed methodology.

  3. Computational time reduction for sequential batch solutions in GNSS precise point positioning technique

    NASA Astrophysics Data System (ADS)

    Martín Furones, Angel; Anquela Julián, Ana Belén; Dimas-Pages, Alejandro; Cos-Gayón, Fernando

    2017-08-01

    Precise point positioning (PPP) is a well established Global Navigation Satellite System (GNSS) technique that only requires information from the receiver (or rover) to obtain high-precision position coordinates. This is a very interesting and promising technique because eliminates the need for a reference station near the rover receiver or a network of reference stations, thus reducing the cost of a GNSS survey. From a computational perspective, there are two ways to solve the system of observation equations produced by static PPP either in a single step (so-called batch adjustment) or with a sequential adjustment/filter. The results of each should be the same if they are both well implemented. However, if a sequential solution (that is, not only the final coordinates, but also those observed in previous GNSS epochs), is needed, as for convergence studies, finding a batch solution becomes a very time consuming task owing to the need for matrix inversion that accumulates with each consecutive epoch. This is not a problem for the filter solution, which uses information computed in the previous epoch for the solution of the current epoch. Thus filter implementations need extra considerations of user dynamics and parameter state variations between observation epochs with appropriate stochastic update parameter variances from epoch to epoch. These filtering considerations are not needed in batch adjustment, which makes it attractive. The main objective of this research is to significantly reduce the computation time required to obtain sequential results using batch adjustment. The new method we implemented in the adjustment process led to a mean reduction in computational time by 45%.

  4. Relativistic jet models for the BL Lacertae object Mrk 421 during three epochs of observation

    NASA Technical Reports Server (NTRS)

    Mufson, S. L.; Hutter, D. J.; Kondo, Y.; Wisniewski, W. Z.

    1988-01-01

    Coordinated observation of the nearby BL Lacertae object Mrk 421 obtained during May 1980, January 1984, and March 1984 are described. These observations give a time-frozen picture of the continuous spectrum of Mrk 421 at X-ray, ultraviolet, optical, and radio wavelengths. The observed spectra have been fitted to an inhomogeneous relativistic jet model. In general, the models reproduce the data well. Many of the observed differences during the three epochs can be attributed to variations in the opening angle of the jet and in the angle that the jet makes to the line of sight. The jet models obtained here are compared with the homogeneous, spherically symmetric, synchrotron self-Compton models for this source. The models are also compared with the relativistic jet models obtained for other active galactic nuclei.

  5. Search for Terrestrial Planets with SIM Planet Quest

    NASA Technical Reports Server (NTRS)

    Shao, Michael; Tanner, Angelle M.; Catanzarite, Joseph H.

    2006-01-01

    SIM is an astrometric mission that will be capable of 1 microarcsec relative astrometric accuracy in a single measurement of approx.1000 sec. The search for terrestrial planets in the habitable zone around nearby stars is one of the main science goals of the project. In 2001, NASA through the peer review process selected 10 key projects, two of which had as its goal, the search for terrestrial planets around nearby stars. The two teams, one led by G. Marcy (UC Berkeley) and one lead by M. Shao (JPL), have an extensive preparatory science program underway. This paper describes the status of this activity as well as the technology status of SIM's narrow angle astrometry capability, to reach 1 uas in a single epoch measure and its ability to average multiple epoch measurements to well below 1 uas.

  6. The 1975 report on active and planned spacecraft and experiments. [index

    NASA Technical Reports Server (NTRS)

    Horowitz, R. (Editor); Davis, L. R. (Editor)

    1975-01-01

    Information is presented on current and planned spacecraft activity for various disciplines: astronomy, earth sciences, meteorology, planetary sciences, aeronomy, solar physics, and life sciences. For active orbiting spacecraft, the epoch date, orbit type, orbit period, apoasis, periapsis, and inclination are given along with the spacecraft weight, launch date, launch site, launch vehicle, and sponsoring agency. For each planned orbiting spacecraft, the orbit parameters, planned launch date, launch site, launch vehicle, spacecraft weight, and sponsoring agency are given.

  7. Reconstructing Environmental Change Using Lake Varves as a Climate Proxy

    ERIC Educational Resources Information Center

    Dempsey, Christopher; Bodzin, Alec; Cirucci, Lori; Anastasio, David; Sahagian, Dork

    2012-01-01

    In this article, the authors describe an investigative activity in which their eighth-grade students reconstructed past environmental change in the New England area using data from lake varves in central Vermont to examine evidence of climate change. The investigation uses an authentic paleoclimate record (Ridge 2011) from the Pleistocene epoch,…

  8. Hydrological Process of Martian Surface in Hesperian epoch

    NASA Astrophysics Data System (ADS)

    Yamashiki, Y. A.; Sato, H.; Kuroki, R.; Miyamoto, H.; Hemmi, R.

    2017-12-01

    It is considered that the Mars in Noachian ecoch was much warmer temperature than current condition, with atmosphere and ocean supported by its magnetic actiity. Several valley which seems to be developed by ancient hydrological processes are obsered in Martian surface, is being considered to be built long time before. Some fluvial fun was formed during the following Hesperian epoch, which is considered as much cooler and drier than Noachian epoch. In this study, we applied Hydro-debris 2D model into Martian surface in Hesperian epoch in order to try develping surface vallay formation throughout hydrological processes. Sediment transport and associated small-scale debris-flow occurrence may be the key for valley formation, where might be the micro-habitable zone.

  9. Increased oscillatory theta activation evoked by violent digital game events.

    PubMed

    Salminen, Mikko; Ravaja, Niklas

    2008-04-11

    The authors examined electroencephalographic (EEG) oscillatory responses to two violent events, the player character wounding and killing an opponent character with a gun, in the digital game James Bond 007: NightFire. EEG was recorded from 25 (16 male) right-handed healthy young adults. EEG data were segmented into one 1-s baseline epoch before each event and two 1-s epochs after event onset. Power estimates (microV(2)) were derived with the fast Fourier transform (FFT) for each artefact free event. Both of the studied events evoked increased occipital theta (4-6Hz) responses as compared to the pre-event baseline. The wounding event evoked also increased occipital high theta (6-8Hz) response and the killing event evoked low alpha (8-10Hz) asymmetry over the central electrodes, both relative to the pre-event baseline. The results are discussed in light of facial electromyographic and electrodermal activity responses evoked by these same events, and it is suggested that the reported EEG responses may be attributable to affective processes related to these violent game events.

  10. Gasdynamic Inlet Isolation in Rotating Detonation Engine

    DTIC Science & Technology

    2010-12-01

    2D Total Variation Diminishing (TVD): Continuous Riemann Solver Minimum Dissipation: LHS & RHS Activate pressure switch : Supersonic Activate...Total Variation Diminishing (TVD) limiter: Continuous Riemann Solver Minimum Dissipation: LHS & RHS Activate pressure switch : Supersonic Activate...Continuous 94 Riemann Solver Minimum Dissipation: LHS & RHS Activate pressure switch : Supersonic Activate pressure gradient switch: Normal

  11. Origin of low proton-to-electron temperature ratio in the Earth's plasma sheet

    NASA Astrophysics Data System (ADS)

    Grigorenko, E. E.; Kronberg, E. A.; Daly, P. W.; Ganushkina, N. Yu.; Lavraud, B.; Sauvaud, J.-A.; Zelenyi, L. M.

    2016-10-01

    We study the proton-to-electron temperature ratio (Tp/Te) in the plasma sheet (PS) of the Earth's magnetotail using 5 years of Cluster observations (2001-2005). The PS intervals are searched within a region defined with -19 < X ≤ -7 RE and |Y| < 15 RE (GSM) under the condition |BX| ≤ 10 nT. One hundred sixty PS crossings are identified. We find an average value of 6.0. However, in many PS intervals Tp/Te varies over a wide range from a few units to several tens of units. In 86 PS intervals the Tp/Te decreases below 3.5. Generally, the decreases of Tp/Te are due to some increase of Te while Tp either decreases or remains unchanged. In the majority of these intervals the Tp/Te drops are observed during magnetotail dipolarizations. A superposed epoch analysis applied to these events shows that the minimum value of Tp/Te is observed after the dipolarization onset during the "turbulent phase" of dipolarization, when a number of transient BZ pulses are reduced, but the value of BZ is still large and an intensification of wave activity is observed. The Tp/Te drops, and associated increases of Te often coincide either with bursts of broadband electrostatic emissions, which may include electron cyclotron harmonics, or with broadband electromagnetic emission in a frequency range from proton plasma frequency (fpp) up to the electron gyrofrequency (fce). These findings show that the wave activity developing in the current sheet after dipolarization onset may play a role in the additional electron heating and the associated Tp/Te decrease.

  12. Adapting Tropical Forest Policy and Practice in the Context of the Anthropocene: Opportunities and Challenges for the El Yunque National Forest in Puerto Rico

    Treesearch

    Kathleen McGinley

    2017-01-01

    Tropical forest management increasingly is challenged by multiple, complex, intersecting, and in many cases unprecedented changes in the environment that are triggered by human activity. Many of these changes are associated with the Anthropocene—a new geologic epoch in which humans have become a dominating factor in shaping the biosphere. Ultimately, as human activity...

  13. Vibration over the larynx increases swallowing and cortical activation for swallowing.

    PubMed

    Mulheren, Rachel W; Ludlow, Christy L

    2017-09-01

    Sensory input can alter swallowing control in both the cortex and brainstem. Electrical stimulation of superior laryngeal nerve afferents increases reflexive swallowing in animals, with different frequencies optimally effective across species. Here we determined 1 ) if neck vibration overlying the larynx affected the fundamental frequency of the voice demonstrating penetration of vibration into the laryngeal tissues, and 2 ) if vibration, in comparison with sham, increased spontaneous swallowing and enhanced cortical hemodynamic responses to swallows in the swallowing network. A device with two motors, one over each thyroid lamina, delivered intermittent 10-s epochs of vibration. We recorded swallows and event-related changes in blood oxygenation level to swallows over the motor and sensory swallowing cortexes bilaterally using functional near infrared spectroscopy. Ten healthy participants completed eight 20-min conditions in counterbalanced order with either epochs of continuous vibration at 30, 70, 110, 150, and 70 + 110 Hz combined, 4-Hz pulsed vibration at 70 + 110 Hz, or two sham conditions without stimulation. Stimulation epochs were separated by interstimulus intervals varying between 30 and 45 s in duration. Vibration significantly reduced the fundamental frequency of the voice compared with no stimulation demonstrating that vibration penetrated laryngeal tissues. Vibration at 70 and at 150 Hz increased spontaneous swallowing compared with sham. Hemodynamic responses to swallows in the motor cortex were enhanced during conditions containing stimulation compared with sham. As vibratory stimulation on the neck increased spontaneous swallowing and enhanced cortical activation for swallows in healthy participants, it may be useful for enhancing swallowing in patients with dysphagia. NEW & NOTEWORTHY Vibratory stimulation at 70 and 150 Hz on the neck overlying the larynx increased the frequency of spontaneous swallowing. Simultaneously vibration also enhanced hemodynamic responses in the motor cortex to swallows when recorded with functional near-infrared spectroscopy (fNIRS). As vibrotactile stimulation on the neck enhanced cortical activation for swallowing in healthy participants, it may be useful for enhancing swallowing in patients with dysphagia. Copyright © 2017 the American Physiological Society.

  14. Rainfall variability over South-east Asia - connections with Indian monsoon and ENSO extremes: new perspectives

    NASA Astrophysics Data System (ADS)

    Kripalani, R. H.; Kulkarni, Ashwini

    1997-09-01

    Seasonal and annual rainfall data for 135 stations for periods varying from 25 to 125 years are utilized to investigate and understand the interannual and short-term (decadal) climate variability over the South-east Asian domain. Contemporaneous relations during the summer monsoon period (June to September) reveal that the rainfall variations over central India, north China, northern parts of Thailand, central parts of Brunei and Borneo and the Indonesian region east of 120°E vary in phase. However, the rainfall variations over the regions surrounding the South China Sea, in particular the north-west Philippines, vary in the opposite phase. Possible dynamic causes for the spatial correlation structure obtained are discussed.Based on the instrumental data available and on an objective criteria, regional rainfall anomaly time series for contiguous regions over Thailand, Malaysia, Singapore, Brunei, Indonesia and Philippines are prepared. Results reveal that although there are year-to-year random fluctuations, there are certain epochs of the above- and below-normal rainfall over each region. These epochs are not forced by the El Niño/La Nina frequencies. Near the equatorial regions the epochs tend to last for about a decade, whereas over the tropical regions, away from the Equator, epochs last for about three decades. There is no systematic climate change or trend in any of the series. Further, the impact of El Niño (La Nina) on the rainfall regimes is more severe during the below (above) normal epochs than during the above (below) normal epochs. Extreme drought/flood situations tend to occur when the epochal behaviour and the El Niño/La Nina events are phase-locked.

  15. Single-trial log transformation is optimal in frequency analysis of resting EEG alpha.

    PubMed

    Smulders, Fren T Y; Ten Oever, Sanne; Donkers, Franc C L; Quaedflieg, Conny W E M; van de Ven, Vincent

    2018-02-01

    The appropriate definition and scaling of the magnitude of electroencephalogram (EEG) oscillations is an underdeveloped area. The aim of this study was to optimize the analysis of resting EEG alpha magnitude, focusing on alpha peak frequency and nonlinear transformation of alpha power. A family of nonlinear transforms, Box-Cox transforms, were applied to find the transform that (a) maximized a non-disputed effect: the increase in alpha magnitude when the eyes are closed (Berger effect), and (b) made the distribution of alpha magnitude closest to normal across epochs within each participant, or across participants. The transformations were performed either at the single epoch level or at the epoch-average level. Alpha peak frequency showed large individual differences, yet good correspondence between various ways to estimate it in 2 min of eyes-closed and 2 min of eyes-open resting EEG data. Both alpha magnitude and the Berger effect were larger for individual alpha than for a generic (8-12 Hz) alpha band. The log-transform on single epochs (a) maximized the t-value of the contrast between the eyes-open and eyes-closed conditions when tested within each participant, and (b) rendered near-normally distributed alpha power across epochs and participants, thereby making further transformation of epoch averages superfluous. The results suggest that the log-normal distribution is a fundamental property of variations in alpha power across time in the order of seconds. Moreover, effects on alpha power appear to be multiplicative rather than additive. These findings support the use of the log-transform on single epochs to achieve appropriate scaling of alpha magnitude. © 2018 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  16. Installation Restoration Program Preliminary Assessment Bethel Radio Relay Station, Alaska

    DTIC Science & Technology

    1989-04-01

    third glacial stage of the Pleistocene * Epoch in North America . KNOB - A rounded eminence, as a knoll, hillock, or small hill or mountain. 3 KNOLL...Pleistocene Epoch in North America , after the Illinoian and before the Wisconsinan. SEDGE - Any of the family (Cyperaceae) of grasslike plants often found on...Pleistocene epoch in North America . I 3 GL-IO U I UREFERENCES 1. Department of the Interior List of Geological Survey Geologic and Water SupplY Reports

  17. Changes in the influence of the western Pacific subtropical high on Asian summer monsoon rainfall in the late 1990s

    NASA Astrophysics Data System (ADS)

    Huang, Yanyan; Wang, Bin; Li, Xiaofan; Wang, Huijun

    2017-10-01

    The Year-to-year variability of the western Pacific subtropical high (WPSH) is primarily controlled by atmosphere-ocean interaction (AOI) between the WPSH and the Indo-Pacific warm pool dipole SST anomalies (AOI mode) and the anomalous SST forcing from the equatorial central Pacific (the CP forcing mode). In this study, we show that the impacts of the WPSH variability on Asian summer monsoon rainfall have changed after the late 1990s. Before the late 1990s (the PRE epoch), the WPSH primarily affects East Asian summer monsoon (EASM) and had little influence on Indian summer monsoon (ISM), whereas after the late 1990s (the POST epoch), the WPSH has strengthened its linkage to the ISM while weakened its relationship with the EASM. This epochal change is associated with a change in the leading circulation mode in the Asia-WP region. During the PRE (POST) epoch the WPSH variation is mainly controlled by the AOI (CP forcing) that mainly affects EASM (ISM). The epochal change of the leading mode may be attributed to the change of the ENSO properties in late 1990s: the CP types of El Nino become a leading ENSO mode in the POST epoch. This work provides a new perspective for understanding decadal changes of the ENSO-monsoon relationship through subtropical dynamics.

  18. DR Tauri: Temporal variability of the brightness distribution in the potential planet-forming region

    NASA Astrophysics Data System (ADS)

    Brunngräber, R.; Wolf, S.; Ratzka, Th.; Ober, F.

    2016-01-01

    Aims: We investigate the variability of the brightness distribution and the changing density structure of the protoplanetary disk around DR Tau, a classical T Tauri star. DR Tau is known for its peculiar variations from the ultraviolet (UV) to the mid-infrared (MIR). Our goal is to constrain the temporal variation of the disk structure based on photometric and MIR interferometric data. Methods: We observed DR Tau with the MID-infrared Interferometric instrument (MIDI) at the Very Large Telescope Interferometer (VLTI) at three epochs separated by about nine years, two months, respectively. We fit the spectral energy distribution and the MIR visibilities with radiative transfer simulations. Results: We are able to reproduce the spectral energy distribution as well as the MIR visibility for one of the three epochs (third epoch) with a basic disk model. We were able to reproduce the very different visibility curve obtained nine years earlier with a very similar baseline (first epoch), using the same disk model with a smaller scale height. The same density distribution also reproduces the observation made with a higher spatial resolution in the second epoch, I.e. only two months before the third epoch. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere, Chile, under the programs 074.C-0342(A) and 092.C-0726(A,B).

  19. Effects of tectonic plate deformation on the geodetic reference frame of Mexico

    NASA Astrophysics Data System (ADS)

    Gonzalez Franco, G. A.; Avalos, D.; Esquivel, R.

    2013-05-01

    Positioning for geodetic applications is commonly determined at one observation epoch, but tectonic drift and tectonic deformation cause the coordinates to be different for any other epoch. Finding the right coordinates at a different epoch from that of the observation time is necessary in Mexico in order to comply the official reference frame, which requires all coordinates to be referred to the standard epoch 2010.0. Available models of horizontal movement in rigid tectonic plates are used to calculate the displacement of coordinates; however for a portion of Mexico these models fail because of miss-modeled regional deformation, decreasing the quality of users' data transformed to the standard epoch. In this work we present the progress achieved in measuring actual horizontal motion towards an improved modeling of horizontal displacements for some regions. Miss-modeled velocities found are as big as 23mm/a, affecting significantly applications like cadastral and geodetic control. Data from a large set of GNSS permanent stations in Mexico is being analyzed to produce the preliminary model of horizontal crustal movement that will be used to minimize distortions of the reference frame.

  20. A jackknife approach to quantifying single-trial correlation between covariance-based metrics undefined on a single-trial basis.

    PubMed

    Richter, Craig G; Thompson, William H; Bosman, Conrado A; Fries, Pascal

    2015-07-01

    The quantification of covariance between neuronal activities (functional connectivity) requires the observation of correlated changes and therefore multiple observations. The strength of such neuronal correlations may itself undergo moment-by-moment fluctuations, which might e.g. lead to fluctuations in single-trial metrics such as reaction time (RT), or may co-fluctuate with the correlation between activity in other brain areas. Yet, quantifying the relation between moment-by-moment co-fluctuations in neuronal correlations is precluded by the fact that neuronal correlations are not defined per single observation. The proposed solution quantifies this relation by first calculating neuronal correlations for all leave-one-out subsamples (i.e. the jackknife replications of all observations) and then correlating these values. Because the correlation is calculated between jackknife replications, we address this approach as jackknife correlation (JC). First, we demonstrate the equivalence of JC to conventional correlation for simulated paired data that are defined per observation and therefore allow the calculation of conventional correlation. While the JC recovers the conventional correlation precisely, alternative approaches, like sorting-and-binning, result in detrimental effects of the analysis parameters. We then explore the case of relating two spectral correlation metrics, like coherence, that require multiple observation epochs, where the only viable alternative analysis approaches are based on some form of epoch subdivision, which results in reduced spectral resolution and poor spectral estimators. We show that JC outperforms these approaches, particularly for short epoch lengths, without sacrificing any spectral resolution. Finally, we note that the JC can be applied to relate fluctuations in any smooth metric that is not defined on single observations. Copyright © 2015. Published by Elsevier Inc.

  1. Hard X-Ray Lightcurves of High Mass X-Ray Binaries

    NASA Technical Reports Server (NTRS)

    Laycock, S.; Coe, M. J.; Harmon, B. A.; Finger, M.; Wilson-Hodge, C.; Rose, M. Franklin (Technical Monitor)

    2001-01-01

    Using the 7.2 years of continuous data now available from the Burst And Transient Source Experiment (BATSE) aboard CGRO, we have measured orbital periods and produced folded lightcurves for 8 High Mass X-ray Binaries (HMXB). Given the length of the datasets, our determinations are based on many more binary orbits than previous investigations. Thus our source detections have high statistical significance and we are able to follow long-term trends in X-ray output. In particular we focus on two systems: A0538-668 and EXO2030+375 both HMXBs exhibiting Type I outbursts. Recent work on A0538-668 (Alcock et al 1999) reported a 16.65d optical variability due to the orbital period, but only seen during minima of a longer-term variability at 421d. We searched for this signal in the BATSE dataset using an ephemeris derived from Alcock et al ( 1999) & Skinner ( 1982). We found no evidence for such modulation and place an upper limit of 3.0 x 10(exp -3) photon/sq cm.s in the 20-70 keV BATSE energy band , based upon statistical modelling of the signal. EXO2030+375 has exhibited an X-ray active epoch, followed by a quiescent period lasting 2.5yr and since April 1996 has exhibited renewed activity. Previous observations (Reig et a 1998) using RXTE ASM data indicate secondary outbursts occur at apastron passage during the current epoch, but not in the former. We present a lightcurve for the earlier epoch showing convincing evidence for such apastron outbursts. We find apastron outbursts in 3 sources, all having orbital periods greater than 41d. No such signal is conclusively detected in the more rapidly orbiting systems studied.

  2. A process model of technology innovation in governmental agencies: Insights from NASA’s science directorate

    NASA Astrophysics Data System (ADS)

    Szajnfarber, Zoe; Weigel, Annalisa L.

    2013-03-01

    This paper investigates the process through which new technical concepts are matured in the NASA innovation ecosystem. We propose an "epoch-shock" conceptualization as an alternative mental model to the traditional stage-gate view. The epoch-shock model is developed inductively, based on detailed empirical observations of the process, and validated, to the extent possible, through expert review. The paper concludes by illustrating how the new epoch-shock conceptualization could provide a useful basis for rethinking feasible interventions to improve innovation management in the space agency context. Where the more traditional stage-gate model leads to an emphasis on centralized flow control, the epoch-shock model acknowledges the decentralized, probabilistic nature of key interactions and highlights which aspects may be influenced.

  3. Recurrent Cosmic-ray Variations as a Probe of the Heliospheric Magnetic Field

    NASA Astrophysics Data System (ADS)

    Burger, R. A.; Engelbrecht, E. E.

    2006-12-01

    A linear relationship between the observed 26-day recurrent cosmic-ray intensity variations and the global latitudinal gradient was first reported by Zhang (1997, ApJ, 488), who made extensive use of Ulysses data. This relationship is seen for all species considered and at all latitudes covered by the spacecraft. Burger and Hitge (2004, ApJL, 617) used a three-dimensional steady-state numerical modulation model and showed that a Fisk-type (Fisk 1996, JGR, 101) heliospheric magnetic field (HMF) can in principle explain these observations, at least at high latitudes. In this progress report we use a refinement of the Fisk-Parker hybrid HMF model of Burger and Hitge (2004) by Kruger (2006, MSc dissertation, NWU University) (see also Kruger, Burger and Hitge 2005, AGU Fall meeting abstracts SH23B-0341) to study these 26-day recurrent variations in more detail with the same modulation code. In Kruger's model the HMF is Parker-like at the highest latitudes, becomes Fisk- like at intermediate latitudes, and becomes Parker-like again in the region swept out by the wavy current sheet. By using an almost continuous range of latitudinal gradients for both solar magnetic polarity cycles and for both protons and electrons - in contrast to the limited number of values used by Burger and Hitge (2004) - the structure of the graphs of amplitude of the recurrent cosmic-ray intensity variations as function of global latitudinal gradient can be studied in detail. This was performed in a 100 AU model heliosphere for solar minimum conditions with the tilt angle of the heliospheric current sheet at 10 degrees. In all cases drift effects are included. We find that these curves for amplitude vs. latitudinal gradient are similar for protons and for electrons. By switching the sign of the modeled amplitudes when the latitudinal gradient becomes negative, the existence of a single relationship between the two quantities can be studied for the whole range of modeled latitudinal gradients. This study shows that a single second-order fit gives better results than a first-order fit for the whole range of latitudinal gradients (and consequently for both species and both solar magnetic polarities) and that there is a difference in the amplitudes for high- and for low rigidities, even if the latitudinal gradient is the same. This difference is a minimum at latitudes where the Fisk-type field is expected to dominate. In the ecliptic at 1 AU, we find that at high rigidity, the amplitude of the recurrent variations is larger for protons during A > 0 polarity epochs than for A < 0 epochs. This is in agreement with observational results of Richardson, Cane and Wibberenz (1999, JGR, 104). For the case of a Parker field, the modeled amplitudes have about the same magnitude for both polarity epochs. Note that what we discus here are preliminary results, and while they clearly suggest the existence of a Fisk-type HMF, the role of the diffusion tensor (and the associated turbulence quantities) has yet to be determined.

  4. The Pandora Effect: The Power and Peril of Curiosity.

    PubMed

    Hsee, Christopher K; Ruan, Bowen

    2016-05-01

    Curiosity-the desire for information-underlies many human activities, from reading celebrity gossip to developing nuclear science. Curiosity is well recognized as a human blessing. Is it also a human curse? Tales about such things as Pandora's box suggest that it is, but scientific evidence is lacking. In four controlled experiments, we demonstrated that curiosity could lead humans to expose themselves to aversive stimuli (even electric shocks) for no apparent benefits. The research suggests that humans possess an inherent desire, independent of consequentialist considerations, to resolve uncertainty; when facing something uncertain and feeling curious, they will act to resolve the uncertainty even if they expect negative consequences. This research reveals the potential perverse side of curiosity, and is particularly relevant to the current epoch, the epoch of information, and to the scientific community, a community with high curiosity. © The Author(s) 2016.

  5. GNSS CORS hardware and software enabling new science

    NASA Astrophysics Data System (ADS)

    Drummond, P.

    2009-12-01

    GNSS CORS networks are enabling new opportunities for science and public and private sector business. This paper will explore how the newest geodetic monitoring software and GNSS receiver hardware from Trimble Navigation Ltd are enabling new science. Technology trends and science opportunities will be explored. These trends include the installation of active GNSS control, automation of observations and processing, and the advantages of multi-observable and multi-constellation observations, all performed with the use of off the shelf products and industry standard open-source data formats. Also the possibilities with moving science from an after-the-fact postprocessed model to a real-time epoch-by-epoch solution will be explored. This presentation will also discuss the combination of existing GNSS CORS networks with project specific installations used for monitoring. Experience is showing GNSS is able to provide higher resolution data than previous methods, providing new tools for science, decision makers and financial planners.

  6. Examining Initial Sleep Onset in Primary Insomnia: A Case-Control Study Using 4-Second Epochs

    PubMed Central

    Moul, Douglas E.; Germain, Anne; Cashmere, J. David; Quigley, Michael; Miewald, Jean M.; Buysse, Daniel J.

    2007-01-01

    Study Objectives: To explore the sleep onset process in primary insomnia patients, new rules for scoring 4-second epochs were implemented to score sleep and artifacts during initial sleep onset. Conventional scorings in 20-second and 60-second epochs were also obtained. Methods: The start of the initial 60-second epoch of stage 1 was used to define “time zero” (t0). Sleep onset periods from 11 patients and 11 individually age- and sex-matched controls spanned from 5 minutes before t0 through 29 minutes after t0. Using the new rules, the periods were scored blind to group assignment. This t0 time-referenced the data analysis to one plausible midpoint in the sleep onset process. In parallel, latencies were time-referenced from good night time. Results: Reliability in scoring sleep and artifacts was adequate (kappa = 0.68 & 0.63, respectively, p <0.001). Group differences in sleep latencies were marginal in 60-second and 20-second scoring but significant with a definition of 4-second sleep latency. Patients had more 4-second epochs scored as awake (Mantel-Haenszel χ2 = 271, d.f. = 1, p <0.001) and containing artifact (M-H χ2 = 143, p <0.001). Patients took longer to achieve 30 continuous 4-second epochs of NREM sleep (Breslow χ2 = 4.03, d.f. = 1, p = 0.045) after t0. Patients accumulated sleep more slowly with all 3 scoring rules after t0. A slower rate of accumulating sleep after t0 was detected only with the 4-second scoring (p = 0.047). Conclusions: Evidence was present for momentary state-switching instabilities in the patients during the initial sleep onset process. Using rules for scoring small epochs may reveal such instabilities more readily than traditional scoring methods. Citation: Moul DE; Germain A; Cashmere D; Quigley M; Miewald JM; Buysse DJ. Examining initial sleep onset in primary insomnia: a case-control study using 4-second epochs. J Clin Sleep Med 2007;3(5):479-488. PMID:17803011

  7. Forest conservation and management in the Anthropocene: Conference proceedings

    Treesearch

    V. Alaric Sample; R. Patrick Bixler

    2014-01-01

    Climate change is but one aspect of the Anthropocene, a new epoch in which the effects of human activities have become the predominant force in the global biosphere. More than just an overlay on the traditional concerns of sustainable natural resource management, the uncertainties associated with these effects are creating a "no-analog future" in which much...

  8. Outward Motions of SiO Masers around VX Sgr

    NASA Astrophysics Data System (ADS)

    Su, J. B.; Shen, Z.-Q.; Chen, X.; Jiang, D. R.

    2014-09-01

    We report the proper motions of SiO maser features around VX Sgr from the two-epoch VLBA observations (2006 December 15 and 2007 August 19). The majority of maser feature activities show a trend of outward motions. It is consistent with our previous finding that the outflow may play an important role for SiO maser pumping.

  9. Paleoclimate of the Earth and solar activity

    NASA Astrophysics Data System (ADS)

    Dergachev, V. A.

    2017-09-01

    The paper focuses on climate variations caused by the orbital effect and solar activity over the last one million years and oscillations (warming or cooling) of the climate since the last ice age retreat. Attention is paid to a significant discrepancy in the trend of global temperature change during the modern interglacial epoch (Holocene) obtained by various methods. A long-term cooling trend was observed in the summer temperature of the Northern Hemisphere during the last 2000 years.

  10. Solar activity variations of nocturnal thermospheric meridional winds over Indian longitude sector

    NASA Astrophysics Data System (ADS)

    Madhav Haridas, M. K.; Manju, G.; Arunamani, T.

    2016-09-01

    The night time F-layer base height information from ionosondes located at two equatorial stations Trivandrum (TRV 8.5°N, 77°E) and Sriharikota (SHAR 13.7°N, 80.2°E) spanning over two decades are used to derive the climatology of equatorial nocturnal Thermospheric Meridional Winds (TMWs) prevailing during High Solar Activity (HSA) and Low Solar Activity (LSA) epochs. The important inferences from the analysis are 1) Increase in mean equatorward winds observed during LSA compared to HSA during pre midnight hours; 25 m/s for VE (Vernal Equinox) and 20 m/s for SS (Summer Solstice), AE (autumnal Equinox) and WS (Winter Solstice). 2) Mean wind response to Solar Flux Unit (SFU) is established quantitatively for all seasons for pre-midnight hours; rate of increase is 0.25 m/s/SFU for VE, 0.2 m/s/SFU for SS and WS and 0.08 m/s/SFU for AE. 3) Theoretical estimates of winds for the two epochs are performed and indicate the role of ion drag forcing as a major factor influencing TMWs. 4) Observed magnitude of winds and rate of flux dependencies are compared to thermospheric wind models. 5) Equinoctial asymmetry in TMWs is observed for HSA at certain times, with more equatorward winds during AE. These observations lend a potential to parameterize the wind components and effectively model the winds, catering to solar activity variations.

  11. Identification of the Infrared Counterpart of SGR 1935+2154 with the Hubble Space Telescope

    NASA Astrophysics Data System (ADS)

    Levan, Andrew; Kouveliotou, Chryssa; Fruchter, Andrew

    2018-02-01

    We present deep Hubble Space Telescope observations of a new magnetar source, the soft gamma-repeater SGR 1935+2154, discovered by Swift. We obtained three epochs of observations: while the source was active in 2015 March, during a quiescent period in 2015 August, and during a further active phase in 2016 May. Close to the center of the X-ray error region identified by Chandra, we find a faint (F140W(AB) = 25.3) source, which fades by a factor of ∼2 over the course of 5 months between the first two epochs of observations, before rebrightening during the second active period. If this source is indeed the counterpart to SGR 1935+2154, then it is among the faintest yet located for a magnetar. Our observations are spaced over 1.3 years and enable us to place limits on the source velocity of μ = (60 ± 40) km s‑1 kpc‑1 observations on timescales of a decade can hence probe proper motion limits smaller than the velocities observed for the majority of pulsars. The comparison of the optical/IR and X-ray light curves of the source suggests that emission in the two regimes is associated but not directly correlated, offering support for a magnetospheric versus a fallback disk origin.

  12. EEG Frequency Changes Prior to Making Errors in an Easy Stroop Task

    PubMed Central

    Atchley, Rachel; Klee, Daniel; Oken, Barry

    2017-01-01

    Background: Mind-wandering is a form of off-task attention that has been associated with negative affect and rumination. The goal of this study was to assess potential electroencephalographic markers of task-unrelated thought, or mind-wandering state, as related to error rates during a specialized cognitive task. We used EEG to record frontal frequency band activity while participants completed a Stroop task that was modified to induce boredom, task-unrelated thought, and therefore mind-wandering. Methods: A convenience sample of 27 older adults (50–80 years) completed a computerized Stroop matching task. Half of the Stroop trials were congruent (word/color match), and the other half were incongruent (mismatched). Behavioral data and EEG recordings were assessed. EEG analysis focused on the 1-s epochs prior to stimulus presentation in order to compare trials followed by correct versus incorrect responses. Results: Participants made errors on 9% of incongruent trials. There were no errors on congruent trials. There was a decrease in alpha and theta band activity during the epochs followed by error responses. Conclusion: Although replication of these results is necessary, these findings suggest that potential mind-wandering, as evidenced by errors, can be characterized by a decrease in alpha and theta activity compared to on-task, accurate performance periods. PMID:29163101

  13. Grand average ERP-image plotting and statistics: A method for comparing variability in event-related single-trial EEG activities across subjects and conditions

    PubMed Central

    Delorme, Arnaud; Miyakoshi, Makoto; Jung, Tzyy-Ping; Makeig, Scott

    2014-01-01

    With the advent of modern computing methods, modeling trial-to-trial variability in biophysical recordings including electroencephalography (EEG) has become of increasingly interest. Yet no widely used method exists for comparing variability in ordered collections of single-trial data epochs across conditions and subjects. We have developed a method based on an ERP-image visualization tool in which potential, spectral power, or some other measure at each time point in a set of event-related single-trial data epochs are represented as color coded horizontal lines that are then stacked to form a 2-D colored image. Moving-window smoothing across trial epochs can make otherwise hidden event-related features in the data more perceptible. Stacking trials in different orders, for example ordered by subject reaction time, by context-related information such as inter-stimulus interval, or some other characteristic of the data (e.g., latency-window mean power or phase of some EEG source) can reveal aspects of the multifold complexities of trial-to-trial EEG data variability. This study demonstrates new methods for computing and visualizing grand ERP-image plots across subjects and for performing robust statistical testing on the resulting images. These methods have been implemented and made freely available in the EEGLAB signal-processing environment that we maintain and distribute. PMID:25447029

  14. VLTI-GRAVITY measurements of cool evolved stars

    NASA Astrophysics Data System (ADS)

    Wittkowski, M.; Rau, G.; Chiavassa, A.; Höfner, S.; Scholz, M.; Wood, P. R.; de Wit, W. J.; Eisenhauer, F.; Haubois, X.; Paumard, T.

    2018-06-01

    Context. Dynamic model atmospheres of Mira stars predict variabilities in the photospheric radius and in atmospheric molecular layers which are not yet strongly constrained by observations. Aims: Here we measure the variability of the oxygen-rich Mira star R Peg in near-continuum and molecular bands. Methods: We used near-infrared K-band spectro-interferometry with a spectral resolution of about 4000 obtained at four epochs between post-maximum and minimum visual phases employing the newly available GRAVITY beam combiner at the Very Large Telescope Interferometer (VLTI). Results: Our observations show a continuum radius that is anti-correlated with the visual lightcurve. Uniform disc (UD) angular diameters at a near-continuum wavelength of 2.25 μm are steadily increasing with values of 8.7 ± 0.1 mas, 9.4 ± 0.1 mas, 9.8 ± 0.1 mas, and 9.9 ± 0.1 mas at visual phases of 0.15, 0.36, 0,45, 0.53, respectively. UD diameters at a bandpass around 2.05 μm, dominated by water vapour, follow the near-continuum variability at larger UD diameters between 10.7 mas and 11.7 mas. UD diameters at the CO 2-0 bandhead, instead, are correlated with the visual lightcurve and anti-correlated with the near-continuum UD diameters, with values between 12.3 mas and 11.7 mas. Conclusions: The observed anti-correlation between continuum radius and visual lightcurve is consistent with an earlier study of the oxygen-rich Mira S Lac, and with recent 1D CODEX dynamic model atmosphere predictions. The amplitude of the variation is comparable to the earlier observations of S Lac, and smaller than predicted by CODEX models. The wavelength-dependent visibility variations at our epochs can be reproduced by a set of CODEX models at model phases between 0.3 and 0.6. The anti-correlation of water vapour and CO contributions at our epochs suggests that these molecules undergo different processes in the extended atmosphere along the stellar cycle. The newly available GRAVITY instrument is suited to conducting longer time series observations, which are needed to provide strong constraints on the model-predicted intra- and inter-cycle variability. Based on observations made with the VLT Interferometer at Paranal Observatory under programme IDs 60.A-9176 and 098.D-0647.

  15. Geomagnetic Polarity Epochs: Sierra Nevada II.

    PubMed

    Cox, A; Doell, R R; Dalrymple, G B

    1963-10-18

    Ten new determinations on volcanic extrusions in the Sierra Nevada with potassium-argon ages of 3.1 million years or less indicate that the remanent magnetizations fall into two groups, a normal group in which the remanent magnetization is directed downward and to the north, and a reversed group magnetized up and to the south. Thermomagnetic experiments and mineralogic studies fail to provide an explanation of the opposing polarities in terms of mineralogic control, but rather suggest that the remanent magnetization reflects reversals of the main dipole field of the earth. All available radiometric ages are consistent with this field-reversal hypothesis and indicate that the present normal polarity epoch (N1) as well as the previous reversed epoch (R1) are 0.9 to 1.0 million years long, whereas the previous normal epoch (N2) was at least 25 percent longer.

  16. Geomagnetic polarity epochs: Sierra Nevada II

    USGS Publications Warehouse

    Cox, A.; Doell, Richard R.; Brent, Dalrymple G.

    1963-01-01

    Ten new determinations on volcanic extrusions in the Sierra Nevada with potassium-argon ages of 3.1 million years or less indicate that the remanent magnetizations fall into two groups, a normal group in which the remanent magnetization is directed downward and to the north, and a reversed group magnetized up and to the south. Thermomagnetic experiments and mineralogic studies fail to provide an explanation of the opposing polarities in terms of mineralogic control, but rather suggest that the remanent magnetization reflects reversals of the main dipole field of the earth. All available radiometric ages are consistent with this field-reversal hypothesis and indicate that the present normal polarity epoch (N1) as well as the previous reversed epoch (R1) are 0.9 to 1.0 million years long, whereas the previous normal epoch (N2) was at least 25 percent longer.

  17. Quantitative Assessment of the CCMC's Experimental Real-time SWMF-Geospace Results

    NASA Astrophysics Data System (ADS)

    Liemohn, Michael; Ganushkina, Natalia; De Zeeuw, Darren; Welling, Daniel; Toth, Gabor; Ilie, Raluca; Gombosi, Tamas; van der Holst, Bart; Kuznetsova, Maria; Maddox, Marlo; Rastaetter, Lutz

    2016-04-01

    Experimental real-time simulations of the Space Weather Modeling Framework (SWMF) are conducted at the Community Coordinated Modeling Center (CCMC), with results available there (http://ccmc.gsfc.nasa.gov/realtime.php), through the CCMC Integrated Space Weather Analysis (iSWA) site (http://iswa.ccmc.gsfc.nasa.gov/IswaSystemWebApp/), and the Michigan SWMF site (http://csem.engin.umich.edu/realtime). Presently, two configurations of the SWMF are running in real time at CCMC, both focusing on the geospace modules, using the BATS-R-US magnetohydrodynamic model, the Ridley Ionosphere Model, and with and without the Rice Convection Model for inner magnetospheric drift physics. While both have been running for several years, nearly continuous results are available since July 2015. Dst from the model output is compared against the Kyoto real-time Dst, in particular the daily minimum value of Dst to quantify the ability of the model to capture storms. Contingency tables are presented, showing that the run with the inner magnetosphere model is much better at reproducing storm-time values. For disturbances with a minimum Dst lower than -50 nT, this version yields a probability of event detection of 0.86 and a Heidke Skill Score of 0.60. In the other version of the SWMF, without the inner magnetospheric module included, the modeled Dst never dropped below -50 nT during the examined epoch.

  18. 'Anthropocene': An Ethical Crisis, Not a Geological Epoch

    NASA Astrophysics Data System (ADS)

    Cuomo, Chris

    2017-04-01

    The term 'anthropocene' has gained enormous popularity among scientists who believe we are in a global phase distinguished by the extensive and lasting impacts of social activities on Earth's sedimentary record and vital systems. Beyond its widespread informal use, a working group of the International Union of Geological Sciences seeks to formalize the term to name a new geological epoch, implying that the Holocene epoch has ended. I argue that the move to formalize the 'anthropocene' and to declare the demise of the Holocene is premature and ethically misguided, at best, and that the very name 'anthropocene' obscures rather than illuminates the serious moral and political/economic implications of the dire warnings evident in recent stratigraphic and ecological changes. If human-caused mass extinction and other ecological catastrophes are serious harms, ethical responses are required. Instead, the move to formalize the idea of an 'anthropocene' epoch treats dire ethical warnings as an opportunity to redefine the current dangerous situation as a new status quo. Have we met our responsibilities to protect Holocene Earth? This presentation will focus on the ethical implications of using the power and discourse of geology to demote Holocene ecological states from their role as the foundational benchmarks for guiding and assessing human relationships with nature and other species. Have geoscientists adequately consulted the biological, ecological and social sciences before declaring the end of the Holocene epoch? Upon what do we base environmental ethics if the Holocene is considered past history? I will also examine the ethical dimensions of naming the so-called 'anthropocene', asking: who is the presumed 'anthro' in the 'anthropocene'? Are the phenomena identified with the 'anthropocene' (nuclear fallout, mass species endangerment, ocean acidification, fossil fuel pollution, deforestation, mining) definitive accomplishments of the human species? Should the practices and institutions that have created enduring marks in the sedimentary record, and that currently endanger global ecological health, be identified as 'human' rather than colonial, modern, industrial, capitalist, etc.? Rather than asserting that all of humanity is responsible for recent dramatic earth-system changes, and thereby implying that humanity is inevitably dominating and destructive, I argue that more specific and precise analyses and descriptions of the causes and forces behind troubling stratigraphic and ecological signals are required, so as to assess responsibility, take responsibility, and better support and restore the health and resiliencies of Earth's physical and living systems.

  19. An Analytic Formulation of the 21 cm Signal from the Early Phase of the Epoch of Reionization

    NASA Astrophysics Data System (ADS)

    Raste, Janakee; Sethi, Shiv

    2018-06-01

    We present an analytic formulation to model the fluctuating component of the H I signal from the epoch of reionization during the phase of partial heating. During this phase, we assume self-ionized regions, whose size distribution can be computed using excursion set formalism, to be surrounded by heated regions. We model the evolution of the heating profile around these regions (near zone) and their merger into the time-dependent background (far zone). We develop a formalism to compute the two-point correlation function for this topology, taking into account the heating autocorrelation and heating-ionization cross-correlation. We model the ionization and X-ray heating using four parameters: efficiency of ionization, ζ number of X-ray photons per stellar baryon, N heat; spectral index of X-ray photons, α and minimum frequency of X-ray photons, ν min. We compute the H I signal in the redshift range 10 < z < 20 for the ΛCDM model for a set of these parameters. We show that the H I signal for a range of scales 1–8 Mpc shows a peak strength of 100–1000 (mK)2 during the partially heated era. The redshift at which the signal makes a transition to a uniformly heated universe depends on the modeling parameters; e.g., if ν min is changed from 100 eV to 1 keV, this transition moves from z ≃ 15 to z ≃ 12. This result, along with the dependence of the H I signal on the modeling parameters, is in reasonable agreement with existing results from N-body simulations.

  20. Optical Polarization and Spectral Variability in the M87 Jet

    NASA Technical Reports Server (NTRS)

    Perlman, Eric S.; Adams, Steven C.; Cara, Mihai; Bourque, Matthew; Harris, D. E.; Madrid, Juan P.; Simons, Raymond C.; Clausen-Brown, Eric; Cheung, C. C.; Stawarz, Lukasz; hide

    2011-01-01

    During the last decade, M87's jet has been the site of an extraordinary variability event, with one knot (HST-1) increasing by over a factor 100 in brightness. Variability was also seen on timescales of months in the nuclear flux. Here we discuss the optical-UV polarization and spectral variability of these components, which show vastly different behavior. HST -1 shows a highly significant correlation between flux and polarization, with P increasing from approx 20% at minimum to > 40% at maximum, while the orientation of its electric vector stayed constant. HST-l's optical-UV spectrum is very hard (alpha(sub uv-0) approx. 0.5, F(sub v) varies as (v(exp -alpha)), and displays "hard lags" during epochs 2004.9-2005.5, including the peak of the flare, with soft lags at later epochs. We interpret the behavior of HST-1 as enhanced particle acceleration in a shock, with cooling from both particle aging and the relaxation of the compression. We set 2alpha upper limits of 0.5 delta parsecs and 1.02c on the size and advance speed of the flaring region. The slight deviation of the electric vector orientation from the jet PA, makes it likely that on smaller scales the flaring region has either a double or twisted structure. By contrast, the nucleus displays much more rapid variability, with a highly variable electric vector orientation and 'looping' in the (I, P) plane. The nucleus has a much steeper spectrum ((alpha(sub uv-0) approx. 1.5) but does not show UV-optical spectral variability. Its behavior can be interpreted as either a helical distortion to a steady jet or a shock propagating through a helical jet.

  1. STIS CORONAGRAPHIC IMAGING OF FOMALHAUT: MAIN BELT STRUCTURE AND THE ORBIT OF FOMALHAUT b

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kalas, Paul; Graham, James R.; Fitzgerald, Michael P.

    2013-09-20

    We present new optical coronagraphic data of Fomalhaut obtained with HST/STIS in 2010 and 2012. Fomalhaut b is recovered at both epochs to high significance. The observations include the discoveries of tenuous nebulosity beyond the main dust belt detected to at least 209 AU projected radius, and a ∼50 AU wide azimuthal gap in the belt northward of Fomalhaut b. The two epochs of Space Telescope Imaging Spectrograph (STIS) photometry exclude optical variability greater than 35%. A Markov chain Monte Carlo analysis demonstrates that the orbit of Fomalhaut b is highly eccentric, with e = 0.8 ± 0.1, a =more » 177 ± 68 AU, and q = 32 ± 24 AU. Fomalhaut b is apsidally aligned with the belt and 90% of allowed orbits have mutual inclination ≤36°. Fomalhaut b's orbit is belt crossing in the sky plane projection, but only 12% of possible orbits have ascending or descending nodes within a 25 AU wide belt annulus. The high eccentricity invokes a dynamical history where Fomalhaut b may have experienced a significant dynamical interaction with a hypothetical planet Fomalhaut c, and the current orbital configuration may be relatively short-lived. The Tisserand parameter with respect to a hypothetical Fomalhaut planet at 30 AU or 120 AU lies in the range 2-3, similar to highly eccentric dwarf planets in our solar system. We argue that Fomalhaut b's minimum mass is that of a dwarf planet in order for a circumplanetary satellite system to remain bound to a sufficient radius from the planet to be consistent with the dust scattered light hypothesis. In the coplanar case, Fomalhaut b will collide with the main belt around 2032, and the subsequent emergent phenomena may help determine its physical nature.« less

  2. Revision of IRIS/IDA Seismic Station Metadata

    NASA Astrophysics Data System (ADS)

    Xu, W.; Davis, P.; Auerbach, D.; Klimczak, E.

    2017-12-01

    Trustworthy data quality assurance has always been one of the goals of seismic network operators and data management centers. This task is considerably complex and evolving due to the huge quantities as well as the rapidly changing characteristics and complexities of seismic data. Published metadata usually reflect instrument response characteristics and their accuracies, which includes zero frequency sensitivity for both seismometer and data logger as well as other, frequency-dependent elements. In this work, we are mainly focused studying the variation of the seismometer sensitivity with time of IRIS/IDA seismic recording systems with a goal to improve the metadata accuracy for the history of the network. There are several ways to measure the accuracy of seismometer sensitivity for the seismic stations in service. An effective practice recently developed is to collocate a reference seismometer in proximity to verify the in-situ sensors' calibration. For those stations with a secondary broadband seismometer, IRIS' MUSTANG metric computation system introduced a transfer function metric to reflect two sensors' gain ratios in the microseism frequency band. In addition, a simulation approach based on M2 tidal measurements has been proposed and proven to be effective. In this work, we compare and analyze the results from three different methods, and concluded that the collocated-sensor method is most stable and reliable with the minimum uncertainties all the time. However, for epochs without both the collocated sensor and secondary seismometer, we rely on the analysis results from tide method. For the data since 1992 on IDA stations, we computed over 600 revised seismometer sensitivities for all the IRIS/IDA network calibration epochs. Hopefully further revision procedures will help to guarantee that the data is accurately reflected by the metadata of these stations.

  3. STIS Coronagraphic Imaging of Fomalhaut: Main Belt Structure and the Orbit of Fomalhaut b

    NASA Technical Reports Server (NTRS)

    Kalas, Paul; Graham, James R.; Fitzgerald, Michael P.; Clampin, Mark

    2013-01-01

    We present new optical coronagraphic data of Fomalhaut obtained with HST/STIS in 2010 and 2012. Fomalhaut b is recovered at both epochs to high significance. The observations include the discoveries of tenuous nebulosity beyond the main dust belt detected to at least 209AU projected radius, and a approx. 50AU wide azimuthal gap in the belt northward of Fomalhaut b. The two epochs of Space Telescope Imaging Spectrograph (STIS) photometry exclude optical variability greater than 35%. A Markov chain Monte Carlo analysis demonstrates that the orbit of Fomalhaut b is highly eccentric, with e = 0.8 +/- 0.1, a = 177 +/- 68AU, and q = 32 +/- 24AU. Fomalhaut b is apsidally aligned with the belt and 90% of allowed orbits have mutual inclination <=36 deg. Fomalhaut b's orbit is belt crossing in the sky plane projection, but only 12% of possible orbits have ascending or descending nodes within a 25AU wide belt annulus. The high eccentricity invokes a dynamical history where Fomalhaut b may have experienced a significant dynamical interaction with a hypothetical planet Fomalhaut c, and the current orbital configuration may be relatively short-lived. The Tisserand parameter with respect to a hypothetical Fomalhaut planet at 30AU or 120AU lies in the range 2-3, similar to highly eccentric dwarf planets in our solar system. We argue that Fomalhaut b's minimum mass is that of a dwarf planet in order for a circumplanetary satellite system to remain bound to a sufficient radius from the planet to be consistent with the dust scattered light hypothesis. In the coplanar case, Fomalhaut b will collide with the main belt around 2032, and the subsequent emergent phenomena may help determine its physical nature.

  4. The American Academy of Sleep Medicine Inter-scorer Reliability Program: Respiratory Events

    PubMed Central

    Rosenberg, Richard S.; Van Hout, Steven

    2014-01-01

    Study Objectives: The American Academy of Sleep Medicine (AASM) Inter-scorer Reliability program provides a unique opportunity to compare a large number of scorers with varied levels of experience to determine agreement in the scoring of respiratory events. The objective of this paper is to examine areas of disagreement to inform future revisions of the AASM Manual for the Scoring of Sleep and Associated Events. Methods: The sample included 15 monthly records, 200 epochs each. The number of scorers increased steadily during the period of data collection, reaching more than 3,600 scorers by the final record. Scorers were asked to identify whether an obstructive, mixed, or central apnea; a hypopnea; or no event was seen in each of the 200 epochs. The “correct” respiratory event score was defined as the score endorsed by the most scorers. Percentage agreement with the majority score was determined for each epoch and the mean agreement determined. Results: The overall agreement for scoring of respiratory events was 93.9% (κ = 0.92). There was very high agreement on epochs without respiratory events (97.4%), and the majority score for most of the epochs (87.8%) was no event. For the 364 epochs scored as having a respiratory event, overall agreement that some type of respiratory event occurred was 88.4% (κ = 0.77). The agreement for epochs scored as obstructive apnea by the majority was 77.1% (κ = 0.71), and the most common disagreement was hypopnea rather than obstructive apnea (14.4%). The agreement for hypopnea was 65.4% (κ = 0.57), with 16.4% scoring no event and 14.8% scoring obstructive apnea. The agreement for central apnea was 52.4% (κ = 0.41). A single epoch was scored as a mixed apnea by a plurality of scorers. Conclusions: The study demonstrated excellent agreement among a large sample of scorers for epochs with no respiratory events. Agreement for some type of event was good, but disagreements in scoring of apnea vs. hypopnea and type of apnea were common. A limitation of the analysis is that most of the records had normal breathing. A review of controversial events yielded no consistent bias that might be resolved by a change of scoring rules. Citation: Rosenberg RS; Van Hout S. The American Academy of Sleep Medicine inter-scorer reliability program: respiratory events. J Clin Sleep Med 2014;10(4):447-454. PMID:24733993

  5. Monitoring the Black Hole Binary GRS 1758-258 with INTEGRAL and RXTE

    NASA Technical Reports Server (NTRS)

    Pottschmidt, Katja; Chernyakova, Masha; Lubinski, Piotr; Migliari, Simone; Smith, David M.; Zdziarski, Andrzej A.; Tomsick, John A.; Bezayiff, N.; Kreykenbohm, Ingo; Kretschmar, Peter; hide

    2008-01-01

    The microquasar GRS 1758-258 is one of only three persistent black hole binaries that spend most of their time in the hard spectral state, the other two being Cyg X-l and 1E 1741.7-2942. It therefore provides the rare opportunity for an extensive long term study of this important black hole state which is associated with strong variability and radio jet emission. INTEGRAL has been monitoring the source since the first Galactic Center Deep Exposure season in spring 2003 during two 2-3 months long Galactic Center viewing epochs each year, amounting to 11 epochs including spring of 2008. With the exception of the last epoch quasi-simultaneous RXTE monitoring observations are available as well. Here we present an analysis of the epoch averaged broad band spectra which display considerable long term variability, most notably the occurrence of two soft/off states, extreme examples for the hysteretic behavior of black hole binaries. The hard source spectrum and long exposures allow us to extend the analysis for several epochs to approximately 800 keV using PICsIT data and address the question of the presence of a non-thermal Comptonization component.

  6. Developmental Patterns of Adverse Childhood Experiences and Current Symptoms and Impairment in Youth Referred For Trauma-Specific Services.

    PubMed

    Grasso, Damion J; Dierkhising, Carly B; Branson, Christopher E; Ford, Julian D; Lee, Robert

    2016-07-01

    By the time children reach adolescence, most have experienced at least one type of severe adversity and many have been exposed to multiple types. However, whether patterns of adverse childhood experiences are consistent or change across developmental epochs in childhood is not known. Retrospective reports of adverse potentially traumatic childhood experiences in 3 distinct developmental epochs (early childhood, 0- to 5-years-old; middle childhood, 6- to 12-years-old; and adolescence, 13- to 18-years-old) were obtained from adolescents (N = 3485) referred to providers in the National Child Traumatic Stress Network (NCTSN) for trauma-focused assessment and treatment. Results from latent class analysis (LCA) revealed increasingly complex patterns of adverse/traumatic experiences in middle childhood and adolescence compared to early childhood. Depending upon the specific developmental epoch assessed, different patterns of adverse/traumatic experiences were associated with gender and with adolescent psychopathology (e.g., internalizing/externalizing behavior problems), and juvenile justice involvement. A multiply exposed subgroup that had severe problems in adolescence was evident in each of the 3 epochs, but their specific types of adverse/traumatic experiences differed depending upon the developmental epoch. Implications for research and clinical practice are identified.

  7. VLTI-Pionier Imaging of the Carbon AGB Star R Sculptoris and the Supergiant V766 Centauri

    NASA Astrophysics Data System (ADS)

    Wittkowski, Markus

    2018-04-01

    I will present reconstructed images of the carbon-rich AGB star R Scl and of the supergiant V766 Cen, both recently obtained from VLTI-PIONIER data. The images are compared to state-of-the art atmosphere and wind models. The images of R Scl exhibit a complex structure within the stellar disk. This structure is most likely caused by giant convection cells, resulting in large-scale shock fronts, and their effects on clumpy molecule and dust formation seen against the photosphere. Images of V 766 Cen were obtained at three epochs. The first epoch shows a complex elongated structure within the photospheric disk, consistent with a red supergiant harboring giant photospheric convection cells. The second and third epochs show a qualitatively and quantitatively different structure with significantly increased contrast, which is not compatible with current models of convection. Instead we interpret the 2016 and 2017 epochs as showing a previously suggested close eclipsing companion in front of the primary, which was located behind the primary at the 2014 epoch. Finally, I will show preliminary reconstructed images of a small sample of further red supergiants.

  8. System and method for generating attitude determinations using GPS

    NASA Technical Reports Server (NTRS)

    Cohen, Clark E. (Inventor)

    1996-01-01

    A GPS attitude receiver for determining the attitude of a moving vehicle in conjunction with a first, a second, a third, and a fourth antenna mounted to the moving vehicle. Each of the antennas receives a plurality of GPS signals that each include a carrier component. For each of the carrier components of the received GPS signals there is an integer ambiguity associated with the first and fourth antennas, an integer ambiguity associated with second and fourth antennas, and an integer ambiguity associated with the third and fourth antennas. The GPS attitude receiver measures phase values for the carrier components of the GPS signals received from each of the antennas at a plurality of measurement epochs during an initialization period and at a measurement epoch after the initialization period. In response to the phase values measured at the measurement epochs during the initialization period, the GPS attitude receiver computes integer ambiguity resolution values representing resolution of the integer ambiguities. Then, in response to the computed integer ambiguity resolution values and the phase value measured at the measurement epoch after the initialization period, it computes values defining the attitude of the moving vehicle at the measurement epoch after the initialization period.

  9. The James Webb Space Telescope Mission

    NASA Technical Reports Server (NTRS)

    Greenhouse, Matt

    2017-01-01

    The universe is 13.7 billion years old. Hubble can look back in time to observe an epoch during which the universe was approximately 1 billion years old, and has seen some galaxies at even earlier epochs.

  10. Time-Resolved Surveys of Stellar Clusters

    NASA Astrophysics Data System (ADS)

    Eyer, Laurent; Eggenberger, Patrick; Greco, Claudia; Saesen, Sophie; Anderson, Richard I.; Mowlavi, Nami

    We describe the information that can be gained when a survey is done multi-epoch, and its particular impact in open cluster research. We first explain the irreplaceable information that multi-epoch observations are giving within astrometry, photometry and spectroscopy. Then we give three examples of results on open clusters from multi-epoch surveys, namely, the distance to the Pleiades, the angular momentum evolution of low mass stars and asteroseismology. Finally we mention several very large surveys, which are ongoing or planned for the future, Gaia, JASMINE, LSST, and VVV.

  11. Solar luminosity variations and the climate of Mars

    NASA Technical Reports Server (NTRS)

    Toon, O. B.; Gierasch, P. J.; Sagan, C.

    1975-01-01

    A simple climatological model of Mars indicates that its climate may be more sensitive to luminosity changes than earth's because of strong positive feedback mechanisms at work on Mars. Mariner 9 photographs of Mars show an abundance of large sinuous channels that point to an epoch of higher atmospheric pressures and abundant liquid water. Such an epoch could have been the result of large-scale solar luminosity variations. The climatological model suggests that other less controversial mechanisms, such as obliquity or polar albedo changes, also could have led to such an epoch.

  12. Study protocol of physical activity and sedentary behaviour measurement among schoolchildren by accelerometry--cross-sectional survey as part of the ENERGY-project.

    PubMed

    Yıldırım, Mine; Verloigne, Maïté; de Bourdeaudhuij, Ilse; Androutsos, Odysseas; Manios, Yannis; Felso, Regina; Kovács, Éva; Doessegger, Alain; Bringolf-Isler, Bettina; te Velde, Saskia J; Brug, Johannes; Chinapaw, Mai J M

    2011-03-25

    Physical activity and sedentary behaviour among children should be measured accurately in order to investigate their relationship with health. Accelerometry provides objective and accurate measurement of body movement, which can be converted to meaningful behavioural outcomes. The aim of this study was to evaluate the best evidence for the decisions on data collection and data processing with accelerometers among children resulting in a standardized protocol for use in the participating countries. This cross-sectional accelerometer study was conducted as part of the European ENERGY-project that aimed to produce an obesity prevention intervention among schoolchildren. Five countries, namely Belgium, Greece, Hungary, Switzerland and the Netherlands participated in the accelerometer study. We used three different Actigraph models--Actitrainers (triaxial), GT3Xs and GT1Ms. Children wore the device for six consecutive days including two weekend days. We selected an epoch length of 15 seconds. Accelerometers were placed at children's waist at the right side of the body in an elastic belt. In total, 1082 children participated in the study (mean age = 11.7 ± 0.75 y, 51% girls). Non-wearing time was calculated as periods of more than 20 minutes of consecutive zero counts. The minimum daily wearing time was set to 10 hours for weekdays and 8 hours for weekend days. The inclusion criterion for further analysis was having at least three valid weekdays and one valid weekend day. We selected a cut-point (count per minute (cpm)) of <100 cpm for sedentary behaviour, <3000 cpm for light, <5200 cpm for moderate, and >5200 cpm for vigorous physical activity. We also created time filters for school-time during data cleaning in order to explore school-time physical activity and sedentary behaviour patterns in particular. This paper describes the decisions for data collection and processing. Use of standardized protocols would ease future use of accelerometry and the comparability of results between studies.

  13. Creation of the Naturalistic Engagement in Secondary Tasks (NEST) distracted driving dataset.

    PubMed

    Owens, Justin M; Angell, Linda; Hankey, Jonathan M; Foley, James; Ebe, Kazutoshi

    2015-09-01

    Distracted driving has become a topic of critical importance to driving safety research over the past several decades. Naturalistic driving data offer a unique opportunity to study how drivers engage with secondary tasks in real-world driving; however, the complexities involved with identifying and coding relevant epochs of naturalistic data have limited its accessibility to the general research community. This project was developed to help address this problem by creating an accessible dataset of driver behavior and situational factors observed during distraction-related safety-critical events and baseline driving epochs, using the Strategic Highway Research Program 2 (SHRP2) naturalistic dataset. The new NEST (Naturalistic Engagement in Secondary Tasks) dataset was created using crashes and near-crashes from the SHRP2 dataset that were identified as including secondary task engagement as a potential contributing factor. Data coding included frame-by-frame video analysis of secondary task and hands-on-wheel activity, as well as summary event information. In addition, information about each secondary task engagement within the trip prior to the crash/near-crash was coded at a higher level. Data were also coded for four baseline epochs and trips per safety-critical event. 1,180 events and baseline epochs were coded, and a dataset was constructed. The project team is currently working to determine the most useful way to allow broad public access to the dataset. We anticipate that the NEST dataset will be extraordinarily useful in allowing qualified researchers access to timely, real-world data concerning how drivers interact with secondary tasks during safety-critical events and baseline driving. The coded dataset developed for this project will allow future researchers to have access to detailed data on driver secondary task engagement in the real world. It will be useful for standalone research, as well as for integration with additional SHRP2 data to enable the conduct of more complex research. Copyright © 2015 Elsevier Ltd and National Safety Council. All rights reserved.

  14. Between-game variation of physical soccer performance measures in highly trained youth soccer players.

    PubMed

    Doncaster, Greg; Unnithan, Viswanath

    2017-07-12

    To assess the between-game variation in measures of physical performance during 11 v 11 soccer match-play, over a short period of time, in highly trained youth soccer players. A single cohort observational study design was employed. Physical match performance data were collected from 17 male, highly trained youth soccer players (age: 13.3 ± 0.4 y) over three, 2 x 20min, 11 v 11 matches. Using 10 Hz GPS, the variables selected for analyses were total distance (TD), high-speed running (HSR), very high-speed running (VHSR), number of high-speed running efforts (HSReff) and number of very high-speed running efforts (VHSReff). Match data was also separated into cumulative 5 min epochs, to identify the peak 5 min epoch and the mean of the cumulative 5 min epochs for each match. Variability was quantified using the coefficient of variation (CV), Standard error of measurement (SEM) and intra-class correlation coefficient (ICC). Between- and within-player smallest worthwhile changes (SWC) were also calculated for each variable to aid in the interpretation of the data. Analysis of the variance between games reported a low CV for TD (3.8%) but larger CVs for HSR (33.3%), HSReff (35.4%) and VHSR and VHSReff (59.6 and 57.4 %, respectively). Analysis of 5 min epochs (peak and average) found an increase in the CVs beyond that of the values reported for the whole match. Between-player SWC in high intensity physical performance data ranged from 24.7 - 42.4 %, whereas within-player SWC ranged from 1.2 - 79.9%. The between-game variability of high and very high intensity activities in youth soccer players, across three soccer matches over a short period of time (2 weeks), is relatively 'large' and specific to the individual, thus highlighting the need for caution when interpreting physical performance data between games and players.

  15. Anthropocene: Shifting Paradigms in Geoscience, Philosophy, History and Geopolitics

    NASA Astrophysics Data System (ADS)

    Maslin, M. A.; Lewis, S. L.

    2015-12-01

    The concept of the Anthropocene has created a profound paradigm shift within the scientific community that we argue will create equally important changes in philosophy, history and politics. There is general scientific agreement that human activity has been a geologically recent, yet profound, influence on the Earth System. The magnitude, variety and longevity of human-induced changes, to the lithosphere, hydrosphere, cryosphere, biosphere and atmosphere suggests that we should refer to the present, not as within the Holocene Epoch (as it is currently formally referred to), but instead as within the Anthropocene Epoch. Discussion is now centred on defining the start of the epoch using the fundamental principles of stratigraphy. These must include (i) a near permanent change to the Earth system that sets it on to a new trajectory and (ii) global changes to the Earth system recorded in a number of stratigraphic deposits worldwide to provide a correlative boundary event or marker called a Global Stratotype Section & Point (GSSP) or 'golden spike'. Using this framework we conclude that just two time-periods are likely adhere to the criteria. These are 1) the irreversible cross-ocean exchange of species alongside the globally synchronous coolest part of the Little Ice Age in the 17th century, marked by the 1610 minima of CO2 (Orbis Spike), and 2) the accelerating atmospheric, oceanic and terrestrial changes in the second half of the 20th century, referred to as the Great Acceleration and conveniently marked by the 1964 peak radionuclide fallout (Bomb Spike). We seek to clear up misconceptions and misunderstandings about geological criteria and relevant evidence that have crept into the literature. We also argue that there are multiple definitions of the Anthropocene and even if a formal definition of the Anthropocene Epoch is agreed by geoscientists, this would in no way invalidate other definitions or uses. It is the utility and wide appeal that makes the Anthropocene such an important concept.

  16. Assessing worst case scenarios in movement demands derived from global positioning systems during international rugby union matches: Rolling averages versus fixed length epochs.

    PubMed

    Cunningham, Daniel J; Shearer, David A; Carter, Neil; Drawer, Scott; Pollard, Ben; Bennett, Mark; Eager, Robin; Cook, Christian J; Farrell, John; Russell, Mark; Kilduff, Liam P

    2018-01-01

    The assessment of competitive movement demands in team sports has traditionally relied upon global positioning system (GPS) analyses presented as fixed-time epochs (e.g., 5-40 min). More recently, presenting game data as a rolling average has become prevalent due to concerns over a loss of sampling resolution associated with the windowing of data over fixed periods. Accordingly, this study compared rolling average (ROLL) and fixed-time (FIXED) epochs for quantifying the peak movement demands of international rugby union match-play as a function of playing position. Elite players from three different squads (n = 119) were monitored using 10 Hz GPS during 36 matches played in the 2014-2017 seasons. Players categorised broadly as forwards and backs, and then by positional sub-group (FR: front row, SR: second row, BR: back row, HB: half back, MF: midfield, B3: back three) were monitored during match-play for peak values of high-speed running (>5 m·s-1; HSR) and relative distance covered (m·min-1) over 60-300 s using two types of sample-epoch (ROLL, FIXED). Irrespective of the method used, as the epoch length increased, values for the intensity of running actions decreased (e.g., For the backs using the ROLL method, distance covered decreased from 177.4 ± 20.6 m·min-1 in the 60 s epoch to 107.5 ± 13.3 m·min-1 for the 300 s epoch). For the team as a whole, and irrespective of position, estimates of fixed effects indicated significant between-method differences across all time-points for both relative distance covered and HSR. Movement demands were underestimated consistently by FIXED versus ROLL with differences being most pronounced using 60 s epochs (95% CI HSR: -6.05 to -4.70 m·min-1, 95% CI distance: -18.45 to -16.43 m·min-1). For all HSR time epochs except one, all backs groups increased more (p < 0.01) from FIXED to ROLL than the forward groups. Linear mixed modelling of ROLL data highlighted that for HSR (except 60 s epoch), SR was the only group not significantly different to FR. For relative distance covered all other position groups were greater than the FR (p < 0.05). The FIXED method underestimated both relative distance (~11%) and HSR values (up to ~20%) compared to the ROLL method. These differences were exaggerated for the HSR variable in the backs position who covered the greatest HSR distance; highlighting important consideration for those implementing the FIXED method of analysis. The data provides coaches with a worst-case scenario reference on the running demands required for periods of 60-300 s in length. This information offers novel insight into game demands and can be used to inform the design of training games to increase specificity of preparation for the most demanding phases of matches.

  17. Be Stars in M31

    NASA Astrophysics Data System (ADS)

    Peters, Matthew L.; Wisniewski, John; Choi, Yumi; Williams, Ben; Lomax, Jamie; Bjorkman, Karen; Durbin, Meredith; Johnson, Lent Cliff; Lewis, Alexia; Lutz, Julie; Sigut, Aaron; Wallach, Aislynn; Dalcanton, Julianne

    2018-01-01

    We identify Be candidate stars in M31 using two-epoch F625W + F658N photometry from HST/ACS+WFC3 combined with the Panchromatic Hubble Andromeda Treasury (PHAT) Catalog. Using the PHAT catalog allows us to extract stellar parameters such as surface temperature and gravity, thereby allowing us to identify the main sequence B type stars in the field of view. Be candidate stars are identified by comparing their HST narrow-band Hα excess magnitudes with that predicted by Kurucz spectra. We find 314 Be candidate stars out of 5699 B + Be candidate stars (5.51%) in our first epoch and 301 Be candidate stars out of 5769 B + Be candidate stars (5.22%) in our second epoch. Our Be fraction, while lower than that of the SMC, LMC, and MW, is possibly consistent with the fact the M31 has a higher metallicity than the other galaxies because Be fraction varies inversely with metallicity. We note that earlier spectral types have the largest Be fraction, and that the Be fraction strictly declines as the spectral type increases to later types. We then match our Be candidate stars with clusters, establishing that 39 of 314 are cluster stars in epoch one and 36 of 301 stars are cluster stars in epoch two. We assign ages, using the cluster age to characterize cluster Be candidate stars and star formation histories to characterize field Be candidate stars. Finally, we determine which Be candidate stars exhibited disk loss or disk growth between epochs, finding that, of the Be stars that did not show source confusion or low SNR in one of the epochs, 65 / 265 (24.5%) showed disk loss or renewal, while 200 / 265 (75.5%) showed only small changes in Hα excess. Our research provides context for the parameters of candidate Be stars in M31, which will be useful in further determining the nature of Be stars. This paper was supported by a grant from STScI via GO-13857.

  18. Odds Ratio Product of Sleep EEG as a Continuous Measure of Sleep State

    PubMed Central

    Younes, Magdy; Ostrowski, Michele; Soiferman, Marc; Younes, Henry; Younes, Mark; Raneri, Jill; Hanly, Patrick

    2015-01-01

    Study Objectives: To develop and validate an algorithm that provides a continuous estimate of sleep depth from the electroencephalogram (EEG). Design: Retrospective analysis of polysomnograms. Setting: Research laboratory. Participants: 114 patients who underwent clinical polysomnography in sleep centers at the University of Manitoba (n = 58) and the University of Calgary (n = 56). Interventions: None. Measurements and Results: Power spectrum of EEG was determined in 3-second epochs and divided into delta, theta, alpha-sigma, and beta frequency bands. The range of powers in each band was divided into 10 aliquots. EEG patterns were assigned a 4-digit number that reflects the relative power in the 4 frequency ranges (10,000 possible patterns). Probability of each pattern occurring in 30-s epochs staged awake was determined, resulting in a continuous probability value from 0% to 100%. This was divided by 40 (% of epochs staged awake) producing the odds ratio product (ORP), with a range of 0–2.5. In validation testing, average ORP decreased progressively as EEG progressed from wakefulness (2.19 ± 0.29) to stage N3 (0.13 ± 0.05). ORP < 1.0 predicted sleep and ORP > 2.0 predicted wakefulness in > 95% of 30-s epochs. Epochs with intermediate ORP occurred in unstable sleep with a high arousal index (> 70/h) and were subject to much interrater scoring variability. There was an excellent correlation (r2 = 0.98) between ORP in current 30-s epochs and the likelihood of arousal or awakening occurring in the next 30-s epoch. Conclusions: Our results support the use of the odds ratio product (ORP) as a continuous measure of sleep depth. Citation: Younes M, Ostrowski M, Soiferman M, Younes H, Younes M, Raneri J, Hanly P. Odds ratio product of sleep EEG as a continuous measure of sleep state. SLEEP 2015;38(4):641–654. PMID:25348125

  19. Paleoclimatological perspective on the hydrometeorology of the Mekong Basin

    NASA Astrophysics Data System (ADS)

    Räsänen, T. A.; Lehr, C.; Mellin, I.; Ward, P. J.; Kummu, M.

    2012-11-01

    During recent decades the Mekong River has experienced substantial interannual variations between droughts and major floods. The causes of these variations have been sought in climate change and dam construction. However, so far little research has addressed whether these recent variations are significantly different to long-term variations in the past. Hence, the aim of our paper is to place the recent variations between droughts and floods into a historical and paleoclimatological context. To achieve this we analysed the Mekong's meteorological conditions over the period 1300-2005 with a basin scale approach by using the Monsoon Asia Drought Atlas (MADA), which is a Palmer Drought Severity Index (PDSI) dataset derived from tree-ring growth records. The correlation analyses, both in time and frequency domains, showed correlation between MADA and the Mekong's discharge over the period 1910-2005 which suggests that MADA can be used as proxy for the hydrometeorology of the Mekong Basin. We found that the meteorological conditions of the Mekong varied at multi-annual, decadal and centennial scales over the study period. We found two especially distinct features: firstly, multi-annual and decadal variation between prolonged wet and dry epochs; and secondly, epochs with higher or lower interannual variability between very dry and wet years. Furthermore we found two epochs with exceptionally large interannual variability, one at the beginning of 17th century and the other in the post 1950 epoch. Both epochs are characterized by distinct increases in variability between very wet and dry years. The variability in the post 1950 epoch is much higher compared to any of the other epochs included in this study. Thus, during recent decades the climate in the Mekong has exhibited features that have not been experienced for at least several centuries. These findings call for further climate research, particularly regarding increased climate variability, and resilient adaptation and development approaches in the basin.

  20. Was the Universe actually radiation dominated prior to nucleosynthesis?

    NASA Astrophysics Data System (ADS)

    Giblin, John T.; Kane, Gordon; Nesbit, Eva; Watson, Scott; Zhao, Yue

    2017-08-01

    Maybe not. String theory approaches to both beyond the Standard Model and inflationary model building generically predict the existence of scalars (moduli) that are light compared to the scale of quantum gravity. These moduli become displaced from their low energy minima in the early Universe and lead to a prolonged matter-dominated epoch prior to big bang nucleosynthesis (BBN). In this paper, we examine whether nonperturbative effects such as parametric resonance or tachyonic instabilities can shorten, or even eliminate, the moduli condensate and matter-dominated epoch. Such effects depend crucially on the strength of the couplings, and we find that unless the moduli become strongly coupled, the matter-dominated epoch is unavoidable. In particular, we find that in string and M-theory compactifications where the lightest moduli are near the TeV scale, a matter-dominated epoch will persist until the time of big bang nucleosynthesis.

  1. Multichannel interictal spike activity detection using time-frequency entropy measure.

    PubMed

    Thanaraj, Palani; Parvathavarthini, B

    2017-06-01

    Localization of interictal spikes is an important clinical step in the pre-surgical assessment of pharmacoresistant epileptic patients. The manual selection of interictal spike periods is cumbersome and involves a considerable amount of analysis workload for the physician. The primary focus of this paper is to automate the detection of interictal spikes for clinical applications in epilepsy localization. The epilepsy localization procedure involves detection of spikes in a multichannel EEG epoch. Therefore, a multichannel Time-Frequency (T-F) entropy measure is proposed to extract features related to the interictal spike activity. Least squares support vector machine is used to train the proposed feature to classify the EEG epochs as either normal or interictal spike period. The proposed T-F entropy measure, when validated with epilepsy dataset of 15 patients, shows an interictal spike classification accuracy of 91.20%, sensitivity of 100% and specificity of 84.23%. Moreover, the area under the curve of Receiver Operating Characteristics plot of 0.9339 shows the superior classification performance of the proposed T-F entropy measure. The results of this paper show a good spike detection accuracy without any prior information about the spike morphology.

  2. A two-step automatic sleep stage classification method with dubious range detection.

    PubMed

    Sousa, Teresa; Cruz, Aniana; Khalighi, Sirvan; Pires, Gabriel; Nunes, Urbano

    2015-04-01

    The limitations of the current systems of automatic sleep stage classification (ASSC) are essentially related to the similarities between epochs from different sleep stages and the subjects' variability. Several studies have already identified the situations with the highest likelihood of misclassification in sleep scoring. Here, we took advantage of such information to develop an ASSC system based on knowledge of subjects' variability of some indicators that characterize sleep stages and on the American Academy of Sleep Medicine (AASM) rules. An ASSC system consisting of a two-step classifier is proposed. In the first step, epochs are classified using support vector machines (SVMs) spread into different nodes of a decision tree. In the post-processing step, the epochs suspected of misclassification (dubious classification) are tagged, and a new classification is suggested. Identification and correction are based on the AASM rules, and on misclassifications most commonly found/reported in automatic sleep staging. Six electroencephalographic and two electrooculographic channels were used to classify wake, non-rapid eye movement (NREM) sleep--N1, N2 and N3, and rapid eye movement (REM) sleep. The proposed system was tested in a dataset of 14 clinical polysomnographic records of subjects suspected of apnea disorders. Wake and REM epochs not falling in the dubious range, are classified with accuracy levels compatible with the requirements for clinical applications. The suggested correction assigned to the epochs that are tagged as dubious enhances the global results of all sleep stages. This approach provides reliable sleep staging results for non-dubious epochs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Magnetic field topology of the cool, active, short-period binary system σ2 Coronae Borealis

    NASA Astrophysics Data System (ADS)

    Rosén, L.; Kochukhov, O.; Alecian, E.; Neiner, C.; Morin, J.; Wade, G. A.; BinaMIcS Collaboration

    2018-06-01

    Aims: The goal of this work is to study the cool, active binary star σ2 CrB, focussing on its magnetic field. The two F9-G0 components of this system are tidally locked and in a close orbit, increasing the chance of interaction between their magnetospheres. Methods: We used Stokes IV data from the twin spectropolarimeters Narval at the TBL and ESPaDOnS at the CFHT. The least-squares deconvolution multi-line technique was used to increase the signal-to-noise ratio of the data. We then applied a new binary Zeeman-Doppler imaging code to reconstruct simultaneously the magnetic topology and brightness distribution of both components of σ2 CrB. This analysis was carried out for two observational epochs in 2014 and 2017. Results: A previously unconfirmed magnetic field of the primary star has been securely detected. At the same time, the polarisation signatures of the secondary appear to have a systematically larger amplitude than that of the primary. This corresponds to a stronger magnetic field, for which the magnetic energy of the secondary exceeds that of the primary by a factor of 3.3-5.7. While the magnetic energy is similar for the secondary star in the two epochs, the magnetic energy is about twice as high in 2017 for the primary. The magnetic field topology of the two stars in the earlier epoch (2014) is very different. The fractions of energy in the dipole and quadrupole components of the secondary are similar and thereafter decrease with increasing harmonic angular degree ℓ. At the same time, for the primary the fraction of energy in the dipole component is low and the maximum energy contribution comes from ℓ = 4. However, in the 2017 epoch both stars have similar field topologies and a systematically decreasing energy with increasing ℓ. In the earlier epoch, the magnetic field at the visible pole appears to be of opposite polarity for the primary and secondary, suggesting linked magnetospheres. The apparent rotational periods of both σ2 CrB components are longer than the orbital period, which we interpret as an evidence of a solar-like differential rotation. Conclusions: Despite their nearly identical fundamental parameters, the components of σ2 CrB system exhibit different magnetic field properties. This indicates that the magnetic dynamo process is a very sensitive function of stellar parameters. Based on observations obtained at the Bernard Lyot Telescope (TBL; Pic du Midi, France) of the Midi-Pyrénées Observatory, which is operated by the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France. Also based on observations obtained at the Canada-France-Hawaii Telescope (CFHT), which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii.

  4. Dark radiation sterile neutrino candidates after Planck data

    NASA Astrophysics Data System (ADS)

    Di Valentino, Eleonora; Melchiorri, Alessandro; Mena, Olga

    2013-11-01

    Recent Cosmic Microwave Background (CMB) results from the Planck satellite, combined with previous CMB data and Hubble constant measurements from the Hubble Space Telescope, provide a constraint on the effective number of relativistic degrees of freedom 3.62+0.50-0.48 at 95% CL. New Planck data provide a unique opportunity to place limits on models containing relativistic species at the decoupling epoch. We present here the bounds on sterile neutrino models combining Planck data with galaxy clustering information. Assuming Neff active plus sterile massive neutrino species, in the case of a Planck+WP+HighL+HST analysis we find mν, sterileeff < 0.36 eV and 3.14 < Neff < 4.15 at 95% CL, while using Planck+WP+HighL data in combination with the full shape of the galaxy power spectrum from the Baryon Oscillation Spectroscopic Survey BOSS Data Relase 9 measurements, we find that 3.30 < Neff < 4.43 and mν, sterileeff < 0.33 eV both at 95% CL with the three active neutrinos having the minimum mass allowed in the normal hierarchy scheme, i.e. ∑mν ~ 0.06 eV. These values compromise the viability of the (3+2) massive sterile neutrino models for the parameter region indicated by global fits of neutrino oscillation data. Within the (3+1) massive sterile neutrino scenario, we find mν, sterileeff < 0.34 eV at 95% CL. While the existence of one extra sterile massive neutrino state is compatible with current oscillation data, the values for the sterile neutrino mass preferred by oscillation analyses are significantly higher than the current cosmological bound. We review as well the bounds on extended dark sectors with additional light species based on the latest Planck CMB observations.

  5. High-resolution VLBA Observations of Three 7 mm SiO Masers toward VX Sgr at Five Epochs

    NASA Astrophysics Data System (ADS)

    Su, J. B.; Shen, Z.-Q.; Chen, X.; Yi, Jiyune; Jiang, D. R.; Yun, Y. J.

    2012-07-01

    VX Sgr is a red supergiant at an adopted distance of 1.6 kpc with intense 43 GHz SiO maser emission. In this paper, we present the high-resolution very long baseline interferometry (VLBI) observations of SiO masers toward VX Sgr at five epochs. We used the Very Long Baseline Array to map the J = 1→0 (v = 1, 2) 28SiO masers and confirmed a ring-like structure. In the first two epochs, the v = 1 masers form a ring, but v = 2 maser spots residing only in the southern and northern regions do not form a complete ring. In the third epoch, the two masers are distributed in a ring structure and the v = 2 masers are a bit closer to the central star. In the last two epochs, many new maser spots appear and overlap each other. These overlapping maser spots can be related to the shock waves and reflect the collisional pumping. We compare the observations with the pumping models and speculate that the real pumping mechanism may be complex in VX Sgr and vary with time. The J = 1→0 (v = 0) 29SiO line emission is also detected, but is too weak to produce any VLBI map.

  6. Independence of amplitude-frequency and phase calibrations in an SSVEP-based BCI using stepping delay flickering sequences.

    PubMed

    Chang, Hsiang-Chih; Lee, Po-Lei; Lo, Men-Tzung; Lee, I-Hui; Yeh, Ting-Kuang; Chang, Chun-Yen

    2012-05-01

    This study proposes a steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) independent of amplitude-frequency and phase calibrations. Six stepping delay flickering sequences (SDFSs) at 32-Hz flickering frequency were used to implement a six-command BCI system. EEG signals recorded from Oz position were first filtered within 29-35 Hz, segmented based on trigger events of SDFSs to obtain SDFS epochs, and then stored separately in epoch registers. An epoch-average process suppressed the inter-SDFS interference. For each detection point, the latest six SDFS epochs in each epoch register were averaged and the normalized power of averaged responses was calculated. The visual target that induced the maximum normalized power was identified as the visual target. Eight subjects were recruited in this study. All subjects were requested to produce the "563241" command sequence four times. The averaged accuracy, command transfer interval, and information transfer rate (mean ± std.) values for all eight subjects were 97.38 ± 5.97%, 3.56 ± 0.68 s, and 42.46 ± 11.17 bits/min, respectively. The proposed system requires no calibration in either the amplitude-frequency characteristic or the reference phase of SSVEP which may provide an efficient and reliable channel for the neuromuscular disabled to communicate with external environments.

  7. The effects of low solar activity upon the cosmic radiation and the interplanetary magnetic field over the past 10,000 years, and implications for the future. (Invited)

    NASA Astrophysics Data System (ADS)

    McCracken, K. G.; McDonald, F. B.; Beer, J.; Abreu, J.; Steinhilber, F.

    2009-12-01

    The paleo-cosmic ray records based on the radionuclides 10Be and 14 C show that the Sun has experienced twenty two extended periods of low activity (similar to, or longer than the Maunder Minimum) in the past 10,000 years, and many more periods of reduced activity for 2 or more solar cycles similar to the period 1880-1910. The 10,000 yr record shows that solar activity has exhibited three persistent periodicities that modulate the amplitude of the Hale (11/22 year) cycle. They are the Gleissberg (~85 yr); the de Vries (~208 yr); and the Hallstatt (~2200 yr) periodicities. It is possible that the Sun is entering a somewhat delayed Gleissberg repetition of the 1880-1910 period of reduced activity or a de Vries repetition of the Dalton Minimum of 1800-1820; or a combination of both. The historic record shows that the cosmic ray intensity at sunspot minimum increases substantially during periods of reduced solar activity- during the Dalton minimum it was twice the present-day sunspot minimum intensity at 2GeV/nucleon ; and 10 times greater at 100 MeV/nucleon. The Hale cycle of solar activity continued throughout the Spoerer (1420-1540) and Maunder Minima, and it appears possible that the local interstellar cosmic ray spectrum was occasionally incident on Earth. Using the cosmic ray transport equation to invert the paleo-cosmic ray record shows that the magnetic field was <1nT at Hale minima during the Spoerer Minimum and late in the Maunder Minimum. The Sun was at a minimum of the Hallstatt (2200yr) cycle of activity in the 15th century, and is now on a steadily rising plane of activity. Paleo-cosmic ray evidence suggests that there was a greater production of impulsive solar energetic particle events in the solar cycles of reduced solar activity 1880-1910. Based on these observations, three scenarios for the next several decades will be outlined- (a) a single, deep sunspot minimum followed by an active sun; (b) several cycles of reduced solar activity similar to 1880-1910; and (c) a “Grand Minimum” with one or more 11 year cycles of very low activity similar to the Dalton Minimum.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, Yue; Liu, Xin; Loeb, Abraham

    We perform a systematic search for sub-parsec binary supermassive black holes (BHs) in normal broad-line quasars at z < 0.8, using multi-epoch Sloan Digital Sky Survey (SDSS) spectroscopy of the broad Hβ line. Our working model is that (1) one and only one of the two BHs in the binary is active; (2) the active BH dynamically dominates its own broad-line region (BLR) in the binary system, so that the mean velocity of the BLR reflects the mean velocity of its host BH; (3) the inactive companion BH is orbiting at a distance of a few R{sub BLR}, where R{submore » BLR} ∼ 0.01-0.1 pc is the BLR size. We search for the expected line-of-sight acceleration of the broad-line velocity from binary orbital motion by cross-correlating SDSS spectra from two epochs separated by up to several years in the quasar rest frame. Out of ∼700 pairs of spectra for which we have good measurements of the velocity shift between two epochs (1σ error ∼40 km s{sup –1}), we detect 28 systems with significant velocity shifts in broad Hβ, among which 7 are the best candidates for the hypothesized binaries, 4 are most likely due to broad-line variability in single BHs, and the rest are ambiguous. Continued spectroscopic observations of these candidates will easily strengthen or disprove these claims. We use the distribution of the observed accelerations (mostly non-detections) to place constraints on the abundance of such binary systems among the general quasar population. Excess variance in the velocity shift is inferred for observations separated by longer than 0.4 yr (quasar rest frame). Attributing all the excess to binary motion would imply that most of the quasars in this sample must be in binaries, that the inactive BH must be on average more massive than the active one, and that the binary separation is at most a few times the size of the BLR. However, if this excess variance is partly or largely due to long-term broad-line variability, the requirement of a large population of close binaries is much weakened or even disfavored for massive companions. Future time-domain spectroscopic surveys of normal quasars can provide vital prior information on the structure function of stochastic velocity shifts induced by broad-line variability in single BHs. Such surveys with improved spectral quality, increased time baseline, and more epochs can greatly improve the statistical constraints of this method on the general binary population in broad-line quasars, further shrink the allowed binary parameter space, and detect true sub-parsec binaries.« less

  9. Spectroscopic planetary detection

    NASA Technical Reports Server (NTRS)

    Deming, D.; Espenak, F.; Hillman, J. J.; Kostiuk, T.; Mumma, M. J.; Jennings, D. E.

    1986-01-01

    The Sun-as-a-star was monitored using the McMath Fourier transform spectometer (FTS) on Kitt Peak in 1983. In 1985 the first measurement was made using the laser heterodyne technique. The FTS measurements now extend for three years, with errors of order 3 meters/sec at a given epoch. Over this 3 year period, a 33 meter/sec change was measured in the apparent velocity of integrated sunlight. The sense of the effect is that a greater blueshift is seen near solar minimum, which is consistent with expectations based on considering the changing morphology of solar granular convection. Presuming this effect is solar-cycle-related, it will mimic the Doppler reflex produced by a planetary companion of approximately two Jupiter masses, with an 11 year orbital period. Thus, Jupiter itself is below the threshold for detection by spectroscopic means, without an additional technique for discrimination. However, for planetary companions in shorter period orbits (P approx. 3 years) the threshold for unambiguous detection is well below one Jupiter mass.

  10. VizieR Online Data Catalog: V and R CCD photometry of visual binaries (Abad+, 2004)

    NASA Astrophysics Data System (ADS)

    Abad, C.; Docobo, J. A.; Lanchares, V.; Lahulla, J. F.; Abelleira, P.; Blanco, J.; Alvarez, C.

    2003-11-01

    Table 1 gives relevant data for the visual binaries observed. Observations were carried out over a short period of time, therefore we assign the mean epoch (1998.58) for the totality of data. Data of individual stars are presented as average data with errors, by parameter, when various observations have been calculated, as well as the number of observations involved. Errors corresponding to astrometric relative positions between components are always present. For single observations, parameter fitting errors, specially for dx and dy parameters, have been calculated analysing the chi2 test around the minimum. Following the rules for error propagation, theta and rho errors can be estimated. Then, Table 1 shows single observation errors with an additional significant digit. When a star does not have known references, we include it in Table 2, where J2000 position and magnitudes are from the USNO-A2.0 catalogue (Monet et al., 1998, Cat. ). (2 data files).

  11. Large Magneto-ionic Variations toward the Galactic Center Magnetar, PSR J1745-2900

    NASA Astrophysics Data System (ADS)

    Desvignes, G.; Eatough, R. P.; Pen, U. L.; Lee, K. J.; Mao, S. A.; Karuppusamy, R.; Schnitzeler, D. H. F. M.; Falcke, H.; Kramer, M.; Wucknitz, O.; Spitler, L. G.; Torne, P.; Liu, K.; Bower, G. C.; Cognard, I.; Lyne, A. G.; Stappers, B. W.

    2018-01-01

    Polarized radio emission from PSR J1745‑2900 has already been used to investigate the strength of the magnetic field in the Galactic center (GC), close to Sagittarius A*. Here we report how persistent radio emission from this magnetar, for over four years since its discovery, has revealed large changes in the observed Faraday rotation measure (RM), by up to 3500 rad m‑2 (a 5% fractional change). From simultaneous analysis of the dispersion measure, we determine that these fluctuations are dominated by variations in either the projected magnetic field or the free electron content within the GC, along the changing line of sight to the rapidly moving magnetar. From a structure function analysis of RM variations, and a recent epoch of rapid change of RM, we determine a minimum scale of magneto-ionic fluctuations of size ∼2 au at the GC distance, inferring PSR J1745‑2900 is just ∼0.1 pc behind an additional scattering screen.

  12. Signal Processing for a Lunar Array: Minimizing Power Consumption

    NASA Technical Reports Server (NTRS)

    D'Addario, Larry; Simmons, Samuel

    2011-01-01

    Motivation for the study is: (1) Lunar Radio Array for low frequency, high redshift Dark Ages/Epoch of Reionization observations (z =6-50, f=30-200 MHz) (2) High precision cosmological measurements of 21 cm H I line fluctuations (3) Probe universe before first star formation and provide information about the Intergalactic Medium and evolution of large scale structures (5) Does the current cosmological model accurately describe the Universe before reionization? Lunar Radio Array is for (1) Radio interferometer based on the far side of the moon (1a) Necessary for precision measurements, (1b) Shielding from earth-based and solar RFI (12) No permanent ionosphere, (2) Minimum collecting area of approximately 1 square km and brightness sensitivity 10 mK (3)Several technologies must be developed before deployment The power needed to process signals from a large array of nonsteerable elements is not prohibitive, even for the Moon, and even in current technology. Two different concepts have been proposed: (1) Dark Ages Radio Interferometer (DALI) (2)( Lunar Array for Radio Cosmology (LARC)

  13. The mean coronal magnetic field determined from Helios Faraday rotation measurements

    NASA Technical Reports Server (NTRS)

    Patzold, M.; Bird, M. K.; Volland, H.; Levy, G. S.; Seidel, B. L.; Stelzried, C. T.

    1987-01-01

    Coronal Faraday rotation of the linearly polarized carrier signals of the Helios spacecraft was recorded during the regularly occurring solar occultations over almost a complete solar cycle from 1975 to 1984. These measurements are used to determine the average strength and radial variation of the coronal magnetic field at solar minimum at solar distances from 3-10 solar radii, i.e., the range over which the complex fields at the coronal base are transformed into the interplanetary spiral. The mean coronal magnetic field in 1975-1976 was found to decrease with radial distance according to r exp-alpha, where alpha = 2.7 + or - 0.2. The mean field magnitude was 1.0 + or - 0.5 x 10 to the -5th tesla at a nominal solar distance of 5 solar radii. Possibly higher magnetic field strengths were indicated at solar maximum, but a lack of data prevented a statistical determination of the mean coronal field during this epoch.

  14. Day-to-day variability of foEs in the equatorial ionosphere

    NASA Astrophysics Data System (ADS)

    Somoye, E. O.; Akala, A. O.; Adeniji-Adele, R. A.; Onori, E. O.; Ogwala, A.; Karimu, A. O.

    2013-09-01

    seasonal, and solar cycle effects of the variability (VR) of the critical frequency of sporadic E layer (foEsq) are investigated at Ibadan (7.4°N, 3.9°E, 6°S dip) in the African sector during high solar activity (HSA) year of 1958 (Rz = 181), moderate solar activity (MSA) year of 1973 (Rz = 30), and low solar activity (LSA) year of 1965 (Rz = 17). The diurnal variation of foEsq VR is characterized by post-midnight (32%-78%) and pre-midnight (20%-84%) peaks during high solar activity (HSA), the only epoch of the three showing these peaks and a diurnal trend. While the daytime foEsq VRs of the three epochs show no seasonal trend, pre-midnight and post-midnight, the foEsq VRs during HSA and LSA show seasonal trends. Similarity is observed in the curve of reciprocal of percentage occurrence of Esq and that of foEsq VR, indicating inverse variation of percentage occurrence and foEsq VR. Longitudinal influence is observed in the diurnal variation of HSA and MSA July foEsq VR of Ibadan (7.4°N, 3.9°E, 6°S dip) in the African sector, which is in the neighborhood of the Greenwich Meridian (GM); Singapore (1.3°N, 108.3°E, 17.6°S dip) in the Asian sector, east of GM; and Huancayo (12°S, 284.7°E, 1.90 dip) in the American sector, west of GM.

  15. Discovery of extreme [O III] λ5007 Å outflows in high-redshift red quasars

    NASA Astrophysics Data System (ADS)

    Zakamska, Nadia L.; Hamann, Fred; Pâris, Isabelle; Brandt, W. N.; Greene, Jenny E.; Strauss, Michael A.; Villforth, Carolin; Wylezalek, Dominika; Alexandroff, Rachael M.; Ross, Nicholas P.

    2016-07-01

    Black hole feedback is now a standard component of galaxy formation models. These models predict that the impact of black hole activity on its host galaxy likely peaked at z = 2-3, the epoch of strongest star formation activity and black hole accretion activity in the Universe. We used XSHOOTER on the Very Large Telescope to measure rest-frame optical spectra of four z ˜ 2.5 extremely red quasars with infrared luminosities ˜1047 erg s-1. We present the discovery of very broad (full width at half max = 2600-5000 km s-1), strongly blueshifted (by up to 1500 km s-1) [O III] λ5007 Å emission lines in these objects. In a large sample of type 2 and red quasars, [O III] kinematics are positively correlated with infrared luminosity, and the four objects in our sample are on the extreme end in both [O III] kinematics and infrared luminosity. We estimate that at least 3 per cent of the bolometric luminosity in these objects is being converted into the kinetic power of the observed wind. Photo-ionization estimates suggest that the [O III] emission might be extended on a few kpc scales, which would suggest that the extreme outflow is affecting the entire host galaxy of the quasar. These sources may be the signposts of the most extreme form of quasar feedback at the peak epoch of galaxy formation, and may represent an active `blow-out' phase of quasar evolution.

  16. The Visual Scoring of Sleep in Infants 0 to 2 Months of Age.

    PubMed

    Grigg-Damberger, Madeleine M

    2016-03-01

    In March 2014, the American Academy of Sleep Medicine (AASM) Board of Directors requested the Scoring Manual Editorial Board develop rules, terminology, and technical specifications for scoring sleep/wake states in full-term infants from birth to 2 mo of age, cognizant of the 1971 Anders, Emde, and Parmelee Manual for Scoring Sleep in Newborns. On July 1, 2015, the AASM published rules for scoring sleep in infants, ages 0-2 mo. This evidence-based review summarizes the background information provided to the Scoring Manual Editorial Board to write these rules. The Anders Manual only provided criteria for coding physiological and behavioral state characteristics in polysomnograms (PSG) of infants, leaving specific sleep scoring criteria to the individual investigator. Other infant scoring criteria have been published, none widely accepted or used. The AASM Scoring Manual infant scoring criteria incorporate modern concepts, digital PSG recording techniques, practicalities, and compromises. Important tenets are: (1) sleep/wake should be scored in 30-sec epochs as either wakefulness (W), rapid eye movement, REM (R), nonrapid eye movement, NREM (N) and transitional (T) sleep; (2) an electroencephalographic (EEG) montage that permits adequate display of young infant EEG is: F3-M2, F4-M1, C3-M2, C4-M1, O1-M2, O2-M1; additionally, recording C3-Cz, Cz-C4 help detect early and asynchronous sleep spindles; (3) sleep onsets are more often R sleep until 2-3 mo postterm; (4) drowsiness is best characterized by visual observation (supplemented by later video review); (5) wide open eyes is the most crucial determinant of W; (6) regularity (or irregularity) of respiration is the single most useful PSG characteristic for scoring sleep stages at this age; (7) trace alternant (TA) is the only relatively distinctive EEG pattern, characteristic of N sleep, and usually disappears by 1 mo postterm replaced by high voltage slow (HVS); (8) sleep spindles first appear 44-48 w conceptional age (CA) and when present prompt scoring N; (9) score EEG activity in an epoch as "continuous" or "discontinuous" for inter-scorer reliability; (10) score R if four or more of the following conditions are present, including irregular respiration and rapid eye movement(s): (a) low chin EMG (for the majority of the epoch); (b) eyes closed with at least one rapid eye movement (concurrent with low chin tone); (c) irregular respiration; (d) mouthing, sucking, twitches, or brief head movements; and (e) EEG exhibits a continuous pattern without sleep spindles; (11) because rapid eye movements may not be seen on every page, epochs following an epoch of definite R in the absence of rapid eye movements may be scored if the EEG is continuous without TA or sleep spindles, chin muscle tone low for the majority of the epoch; and there is no intervening arousal; (12) Score N if four or more of the following conditions are present, including regular respiration, for the majority of the epoch: (a) eyes are closed with no eye movements; (b) chin EMG tone present; (c) regular respiration; and (d) EEG patterns of either TA, HVS, or sleep spindles are present; and (13) score T sleep if an epoch contains two or more discordant PSG state characteristics (either three NREM and two REM characteristics or two NREM and three REM characteristics). These criteria for ages 0-2 mo represent far more than baby steps. Like all the other AASM Manual rules and specifications none are fixed in stone, all open for debate, discussion and revision with the fundamental goal to provide standards for comparison of methods and results. A commentary on this article appears in this issue on page 291. © 2016 American Academy of Sleep Medicine.

  17. Mitochondrial DNA Detects a Complex Evolutionary History with Pleistocene Epoch Divergence for the Neotropical Malaria Vector Anopheles nuneztovari Sensu Lato

    PubMed Central

    Scarpassa, Vera Margarete; Conn, Jan E.

    2011-01-01

    Cryptic species and lineages characterize Anopheles nuneztovari s.l. Gabaldón, an important malaria vector in South America. We investigated the phylogeographic structure across the range of this species with cytochrome oxidase subunit I (COI) mitochondrial DNA sequences to estimate the number of clades and levels of divergence. Bayesian and maximum-likelihood phylogenetic analyses detected four groups distributed in two major monophyletic clades (I and II). Samples from the Amazon Basin were clustered in clade I, as were subclades II-A and II-B, whereas those from Bolivia/Colombia/Venezuela were restricted to one basal subclade (II-C). These data, together with a statistical parsimony network, confirm results of previous studies that An. nuneztovari is a species complex consisting of at least two cryptic taxa, one occurring in Colombia and Venezuela and the another occurring in the Amazon Basin. These data also suggest that additional incipient species may exist in the Amazon Basin. Divergence time and expansion tests suggested that these groups separated and expanded in the Pleistocene Epoch. In addition, the COI sequences clearly separated An. nuneztovari s.l. from the closely related species An. dunhami Causey, and three new records are reported for An. dunhami in Amazonian Brazil. These findings are relevant for vector control programs in areas where both species occur. Our analyses support dynamic geologic and landscape changes in northern South America, and infer particularly active divergence during the Pleistocene Epoch for New World anophelines. PMID:22049039

  18. Frequency domain beamforming of magnetoencephalographic beta band activity in epilepsy patients with focal cortical dysplasia.

    PubMed

    Heers, Marcel; Hirschmann, Jan; Jacobs, Julia; Dümpelmann, Matthias; Butz, Markus; von Lehe, Marec; Elger, Christian E; Schnitzler, Alfons; Wellmer, Jörg

    2014-09-01

    Spike-based magnetoencephalography (MEG) source localization is an established method in the presurgical evaluation of epilepsy patients. Focal cortical dysplasias (FCDs) are associated with focal epileptic discharges of variable morphologies in the beta frequency band in addition to single epileptic spikes. Therefore, we investigated the potential diagnostic value of MEG-based localization of spike-independent beta band (12-30Hz) activity generated by epileptogenic lesions. Five patients with FCD IIB underwent MEG. In one patient, invasive EEG (iEEG) was recorded simultaneously with MEG. In two patients, iEEG succeeded MEG, and two patients had MEG only. MEG and iEEG were evaluated for epileptic spikes. Two minutes of iEEG data and MEG epochs with no spikes as well as MEG epochs with epileptic spikes were analyzed in the frequency domain. MEG oscillatory beta band activity was localized using Dynamic Imaging of Coherent Sources. Intralesional beta band activity was coherent between simultaneous MEG and iEEG recordings. Continuous 14Hz beta band power correlated with the rate of interictal epileptic discharges detected in iEEG. In cases where visual MEG evaluation revealed epileptic spikes, the sources of beta band activity localized within <2cm of the epileptogenic lesion as shown on magnetic resonance imaging. This result held even when visually marked epileptic spikes were deselected. When epileptic spikes were detectable in iEEG but not MEG, MEG beta band activity source localization failed. Source localization of beta band activity has the potential to contribute to the identification of epileptic foci in addition to source localization of visually marked epileptic spikes. Thus, this technique may assist in the localization of epileptic foci in patients with suspected FCD. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Violence in the hearts of galaxies: aberration or adolescence?

    PubMed

    Mundell, Carole G

    2002-12-15

    Violent activity in the nuclei of galaxies has long been considered a curiosity in its own right; manifestations of this phenomenon include distant quasars in the early Universe and comparatively nearby Seyfert galaxies, both thought to be powered by the release of gravitational potential energy as material from the host galaxy accretes onto a central supermassive black hole (SMBH). Traditionally, the broader study of the formation, structure and evolution of galaxies has largely excluded active galactic nuclei. Recently, however, this situation has changed dramatically, both observationally and theoretically, with the realization that the growth and influence of the SMBH, the origin and development of galaxies and nuclear activity at different epochs in the Universe may be intimately related. The most spectacular fireworks seen in distant quasars may be relatively easy to explain, since the era of greatest quasar activity seems to coincide with turbulent dynamics at the epoch of galaxy formation in the young, gas-rich Universe. Ubiquitous black holes are believed to be a legacy of this violent birth. Alternatively, black holes may be the seeds that drive galaxy formation in the first place. Closer to home, and hence more recently in the history of the Universe, a fraction of comparatively ordinary galaxies, similar to our own, has reignited their central engines, albeit at a lower level of activity. Since these galaxies are more established than their younger and more distant counterparts, the activity here is all the more puzzling. Whatever the mechanisms involved, they are likely to play an important role in galaxy evolution. I review the intriguing evidence for causal links between SMBHs, nuclear activity and the formation and evolution of galaxies, and describe opportunities for testing these relationships using the next generation of earthbound and space-borne astronomical facilities.

  20. Assessing worst case scenarios in movement demands derived from global positioning systems during international rugby union matches: Rolling averages versus fixed length epochs

    PubMed Central

    Cunningham, Daniel J.; Shearer, David A.; Carter, Neil; Drawer, Scott; Pollard, Ben; Bennett, Mark; Eager, Robin; Cook, Christian J.; Farrell, John; Russell, Mark

    2018-01-01

    The assessment of competitive movement demands in team sports has traditionally relied upon global positioning system (GPS) analyses presented as fixed-time epochs (e.g., 5–40 min). More recently, presenting game data as a rolling average has become prevalent due to concerns over a loss of sampling resolution associated with the windowing of data over fixed periods. Accordingly, this study compared rolling average (ROLL) and fixed-time (FIXED) epochs for quantifying the peak movement demands of international rugby union match-play as a function of playing position. Elite players from three different squads (n = 119) were monitored using 10 Hz GPS during 36 matches played in the 2014–2017 seasons. Players categorised broadly as forwards and backs, and then by positional sub-group (FR: front row, SR: second row, BR: back row, HB: half back, MF: midfield, B3: back three) were monitored during match-play for peak values of high-speed running (>5 m·s-1; HSR) and relative distance covered (m·min-1) over 60–300 s using two types of sample-epoch (ROLL, FIXED). Irrespective of the method used, as the epoch length increased, values for the intensity of running actions decreased (e.g., For the backs using the ROLL method, distance covered decreased from 177.4 ± 20.6 m·min-1 in the 60 s epoch to 107.5 ± 13.3 m·min-1 for the 300 s epoch). For the team as a whole, and irrespective of position, estimates of fixed effects indicated significant between-method differences across all time-points for both relative distance covered and HSR. Movement demands were underestimated consistently by FIXED versus ROLL with differences being most pronounced using 60 s epochs (95% CI HSR: -6.05 to -4.70 m·min-1, 95% CI distance: -18.45 to -16.43 m·min-1). For all HSR time epochs except one, all backs groups increased more (p < 0.01) from FIXED to ROLL than the forward groups. Linear mixed modelling of ROLL data highlighted that for HSR (except 60 s epoch), SR was the only group not significantly different to FR. For relative distance covered all other position groups were greater than the FR (p < 0.05). The FIXED method underestimated both relative distance (~11%) and HSR values (up to ~20%) compared to the ROLL method. These differences were exaggerated for the HSR variable in the backs position who covered the greatest HSR distance; highlighting important consideration for those implementing the FIXED method of analysis. The data provides coaches with a worst-case scenario reference on the running demands required for periods of 60–300 s in length. This information offers novel insight into game demands and can be used to inform the design of training games to increase specificity of preparation for the most demanding phases of matches. PMID:29621279

  1. Heart-Brain Interactions in the MR Environment: Characterization of the Ballistocardiogram in EEG Signals Collected During Simultaneous fMRI.

    PubMed

    Marino, Marco; Liu, Quanying; Del Castello, Mariangela; Corsi, Cristiana; Wenderoth, Nicole; Mantini, Dante

    2018-05-01

    The ballistocardiographic (BCG) artifact is linked to cardiac activity and occurs in electroencephalographic (EEG) recordings acquired inside the magnetic resonance (MR) environment. Its variability in terms of amplitude, waveform shape and spatial distribution over subject's scalp makes its attenuation a challenging task. In this study, we aimed to provide a detailed characterization of the BCG properties, including its temporal dependency on cardiac events and its spatio-temporal dynamics. To this end, we used high-density EEG data acquired during simultaneous functional MR imaging in six healthy volunteers. First, we investigated the relationship between cardiac activity and BCG occurrences in the EEG recordings. We observed large variability in the delay between ECG and subsequent BCG events (ECG-BCG delay) across subjects and non-negligible epoch-by-epoch variations at the single subject level. The inspection of spatial-temporal variations revealed a prominent non-stationarity of the BCG signal. We identified five main BCG waves, which were common across subjects. Principal component analysis revealed two spatially distinct patterns to explain most of the variance (85% in total). These components are possibly related to head rotation and pulse-driven scalp expansion, respectively. Our results may inspire the development of novel, more effective methods for the removal of the BCG, capable of isolating and attenuating artifact occurrences while preserving true neuronal activity.

  2. Identifying reliable independent components via split-half comparisons

    PubMed Central

    Groppe, David M.; Makeig, Scott; Kutas, Marta

    2011-01-01

    Independent component analysis (ICA) is a family of unsupervised learning algorithms that have proven useful for the analysis of the electroencephalogram (EEG) and magnetoencephalogram (MEG). ICA decomposes an EEG/MEG data set into a basis of maximally temporally independent components (ICs) that are learned from the data. As with any statistic, a concern with using ICA is the degree to which the estimated ICs are reliable. An IC may not be reliable if ICA was trained on insufficient data, if ICA training was stopped prematurely or at a local minimum (for some algorithms), or if multiple global minima were present. Consequently, evidence of ICA reliability is critical for the credibility of ICA results. In this paper, we present a new algorithm for assessing the reliability of ICs based on applying ICA separately to split-halves of a data set. This algorithm improves upon existing methods in that it considers both IC scalp topographies and activations, uses a probabilistically interpretable threshold for accepting ICs as reliable, and requires applying ICA only three times per data set. As evidence of the method’s validity, we show that the method can perform comparably to more time intensive bootstrap resampling and depends in a reasonable manner on the amount of training data. Finally, using the method we illustrate the importance of checking the reliability of ICs by demonstrating that IC reliability is dramatically increased by removing the mean EEG at each channel for each epoch of data rather than the mean EEG in a prestimulus baseline. PMID:19162199

  3. Designing Successful Next-Generation Instruments to Detect the Epoch of Reionization

    NASA Astrophysics Data System (ADS)

    Thyagarajan, Nithyanandan; Hydrogen Epoch of Reionization Array (HERA) team, Murchison Widefield Array (MWA) team

    2018-01-01

    The Epoch of Reionization (EoR) signifies a period of intense evolution of the Inter-Galactic Medium (IGM) in the early Universe caused by the first generations of stars and galaxies, wherein they turned the neutral IGM to be completely ionized by redshift ≥ 6. This important epoch is poorly explored to date. Measurement of redshifted 21 cm line from neutral Hydrogen during the EoR is promising to provide the most direct constraints of this epoch. Ongoing experiments to detect redshifted 21 cm power spectrum during reionization, including the Murchison Widefield Array (MWA), Precision Array for Probing the Epoch of Reionization (PAPER), and the Low Frequency Array (LOFAR), appear to be severely affected by bright foregrounds and unaccounted instrumental systematics. For example, the spectral structure introduced by wide-field effects, aperture shapes and angular power patterns of the antennas, electrical and geometrical reflections in the antennas and electrical paths, and antenna position errors can be major limiting factors. These mimic the 21 cm signal and severely degrade the instrument performance. It is imperative for the next-generation of experiments to eliminate these systematics at their source via robust instrument design. I will discuss a generic framework to set cosmologically motivated antenna performance specifications and design strategies using the Precision Radio Interferometry Simulator (PRISim) -- a high-precision tool that I have developed for simulations of foregrounds and the instrument transfer function intended primarily for 21 cm EoR studies, but also broadly applicable to interferometer-based intensity mapping experiments. The Hydrogen Epoch of Reionization Array (HERA), designed in-part based on this framework, is expected to detect the 21 cm signal with high significance. I will present this framework and the simulations, and their potential for designing upcoming radio instruments such as HERA and the Square Kilometre Array (SKA).

  4. Four "E"pochs: The Story of Informatization.

    ERIC Educational Resources Information Center

    Duff, Alistair S.

    2003-01-01

    Informatization is a term of Japanese provenance denoting major systemic change from the application of information technology. Proposes a theory of post-war informatization focusing on information services in libraries, specifically computerized information retrieval. Describes four electronic epochs: offline, online, CD-ROM, and Internet, and…

  5. Application of COMSOL to Acoustic Imaging

    DTIC Science & Technology

    2010-10-01

    Marquardt (LM) (2 epochs), followed by Broyden, Fletcher, Goldfarb, and Shannon (BFGS) (2 epochs) followed by scaled conjugate gradient ( SCG )(100...Use Matlab’s excellent Neural Network Toolbox  Optimization techniques considered:  Scaled‏Con jugate‏ Gradient‏ (“ SCG ”)‏ - fast  One‏Step

  6. VizieR Online Data Catalog: MOJAVE. VIII. Faraday rotation in AGN jets. (Hovatta+, 2012)

    NASA Astrophysics Data System (ADS)

    Hovatta, T.; Lister, M. L.; Aller, M. F.; Aller, H. D.; Homan, D. C.; Kovalev, Yu. Y.; Pushkarev, A. B.; Savolainen, T.

    2013-10-01

    Our sample consists of 191 AGNs observed within the MOJAVE Very Long Baseline Array (VLBA) survey (Lister et al., 2009, cat. J/AJ/137/3718, Paper V). It includes 134 sources of the complete flux density-limited MOJAVE-1 sample. The rest of the sources belong to the MOJAVE-2 sample (http://www.physics.purdue.edu/astro/MOJAVE/allsources.html), which includes sources from the 2cm survey (Kellermann et al. 2004, cat. J/ApJ/609/539), gamma-ray blazars, and other sources with unusual jet properties. The sources were observed with VLBA in 2006 over 12 epochs with about monthly separation, each epoch containing 18 sources (except for epoch 2006 February 12, which included only 14 sources and epoch 2006 April 28, which included 17 sources). The observations were made in dual polarization mode using frequencies centered at 8.104, 8.424 (X band), 12.119, and 15.369GHz (U band). (2 data files).

  7. Results From PAPER/HERA

    NASA Astrophysics Data System (ADS)

    Pober, Jonathan C.

    2018-05-01

    The Precision Array for Probing the Epoch of Reionization (PAPER) was a first-generation 21 cm cosmology experiment with the specific goal of detecting the power spectrum of the 21 cm emission from the Epoch of Reionization. Analysis of PAPER data is still ongoing, but lessons learned from PAPER to date have played a critical role in designing the next-generation Hydrogen Epoch of Reionization Array (HERA) experiment. This article reviews five key design choices made by PAPER: use of a non-imaging configuration, redundancy, short baselines, small antenna elements, and a large instantaneous bandwidth. We describe the impact of these choices and the role they played in designing HERA.

  8. A Decade of H α Transits for HD 189733 b: Stellar Activity versus Absorption in the Extended Atmosphere

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cauley, P. Wilson; Redfield, Seth; Jensen, Adam G., E-mail: pcauley@wesleyan.edu

    HD 189733 b is one of the most well studied exoplanets due to its large transit depth and host star brightness. The focus on this object has produced a number of high-cadence transit observations using high-resolution optical spectrographs. Here we present an analysis of seven full H α transits of HD 189733 b using HARPS on the 3.6 meter La Silla telescope and HIRES on Keck I, taken over the course of nine years from 2006 to 2015. H α transmission signals are analyzed as a function of the stellar activity level, as measured using the normalized core flux ofmore » the Ca ii H and K lines. We find strong variations in the strength of the H α transmission spectrum from epoch to epoch. However, there is no clear trend between the Ca ii core emission and the strength of the in-transit H α signal, although the transit showing the largest absorption value also occurs when the star is the most active. We present simulations of the in-transit contrast effect and find that the planet must consistently transit active latitudes with very strong facular and plage emission regions in order to reproduce the observed line strengths. We also investigate the measured velocity centroids with models of planetary rotation and show that the small line profile velocities could be due to large velocities in the upper atmosphere of the planet. Overall, we find it more likely that the measured H α signals arise in the extended planetary atmosphere, although a better understanding of active region emission for active stars such as HD 189733 is needed.« less

  9. HIGH-RESOLUTION VLBA OBSERVATIONS OF THREE 7 mm SiO MASERS TOWARD VX Sgr AT FIVE EPOCHS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su, J. B.; Shen, Z.-Q.; Chen, X.

    2012-07-20

    VX Sgr is a red supergiant at an adopted distance of 1.6 kpc with intense 43 GHz SiO maser emission. In this paper, we present the high-resolution very long baseline interferometry (VLBI) observations of SiO masers toward VX Sgr at five epochs. We used the Very Long Baseline Array to map the J = 1{yields}0 (v = 1, 2) {sup 28}SiO masers and confirmed a ring-like structure. In the first two epochs, the v = 1 masers form a ring, but v = 2 maser spots residing only in the southern and northern regions do not form a complete ring.more » In the third epoch, the two masers are distributed in a ring structure and the v = 2 masers are a bit closer to the central star. In the last two epochs, many new maser spots appear and overlap each other. These overlapping maser spots can be related to the shock waves and reflect the collisional pumping. We compare the observations with the pumping models and speculate that the real pumping mechanism may be complex in VX Sgr and vary with time. The J = 1{yields}0 (v = 0) {sup 29}SiO line emission is also detected, but is too weak to produce any VLBI map.« less

  10. The addition of entropy-based regularity parameters improves sleep stage classification based on heart rate variability.

    PubMed

    Aktaruzzaman, M; Migliorini, M; Tenhunen, M; Himanen, S L; Bianchi, A M; Sassi, R

    2015-05-01

    The work considers automatic sleep stage classification, based on heart rate variability (HRV) analysis, with a focus on the distinction of wakefulness (WAKE) from sleep and rapid eye movement (REM) from non-REM (NREM) sleep. A set of 20 automatically annotated one-night polysomnographic recordings was considered, and artificial neural networks were selected for classification. For each inter-heartbeat (RR) series, beside features previously presented in literature, we introduced a set of four parameters related to signal regularity. RR series of three different lengths were considered (corresponding to 2, 6, and 10 successive epochs, 30 s each, in the same sleep stage). Two sets of only four features captured 99 % of the data variance in each classification problem, and both of them contained one of the new regularity features proposed. The accuracy of classification for REM versus NREM (68.4 %, 2 epochs; 83.8 %, 10 epochs) was higher than when distinguishing WAKE versus SLEEP (67.6 %, 2 epochs; 71.3 %, 10 epochs). Also, the reliability parameter (Cohens's Kappa) was higher (0.68 and 0.45, respectively). Sleep staging classification based on HRV was still less precise than other staging methods, employing a larger variety of signals collected during polysomnographic studies. However, cheap and unobtrusive HRV-only sleep classification proved sufficiently precise for a wide range of applications.

  11. Multiepoch Spectropolarimetry of SN 2011fe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milne, Peter A.; Williams, G. Grant; Smith, Paul S.

    2017-01-20

    We present multiple spectropolarimetric observations of the nearby Type Ia supernova (SN) 2011fe in M101, obtained before, during, and after the time of maximum apparent visual brightness. The excellent time coverage of our spectropolarimetry has allowed better monitoring of the evolution of polarization features than is typical, which has allowed us new insight into the nature of normal SNe Ia. SN 2011fe exhibits time-dependent polarization in both the continuum and strong absorption lines. At early epochs, red wavelengths exhibit a degree of continuum polarization of up to 0.4%, likely indicative of a mild asymmetry in the electron-scattering photosphere. This behaviormore » is more common in subluminous SNe Ia than in normal events, such as SN 2011fe. The degree of polarization across a collection of absorption lines varies dramatically from epoch to epoch. During the earliest epoch, a λ 4600–5000 Å complex of absorption lines shows enhanced polarization at a different position angle than the continuum. We explore the origin of these features, presenting a few possible interpretations, without arriving at a single favored ion. During two epochs near maximum, the dominant polarization feature is associated with the Si ii λ 6355 Å absorption line. This is common for SNe Ia, but for SN 2011fe the polarization of this feature increases after maximum light, whereas for other SNe Ia, that polarization feature was strongest before maximum light.« less

  12. The quantum epoché.

    PubMed

    Pylkkänen, Paavo

    2015-12-01

    The theme of phenomenology and quantum physics is here tackled by examining some basic interpretational issues in quantum physics. One key issue in quantum theory from the very beginning has been whether it is possible to provide a quantum ontology of particles in motion in the same way as in classical physics, or whether we are restricted to stay within a more limited view of quantum systems, in terms of complementary but mutually exclusive phenomena. In phenomenological terms we could describe the situation by saying that according to the usual interpretation of quantum theory (especially Niels Bohr's), quantum phenomena require a kind of epoché (i.e. a suspension of assumptions about reality at the quantum level). However, there are other interpretations (especially David Bohm's) that seem to re-establish the possibility of a mind-independent ontology at the quantum level. We will show that even such ontological interpretations contain novel, non-classical features, which require them to give a special role to "phenomena" or "appearances", a role not encountered in classical physics. We will conclude that while ontological interpretations of quantum theory are possible, quantum theory implies the need of a certain kind of epoché even for this type of interpretations. While different from the epoché connected to phenomenological description, the "quantum epoché" nevertheless points to a potentially interesting parallel between phenomenology and quantum philosophy. Copyright © 2015. Published by Elsevier Ltd.

  13. A statistical study of the low-altitude ionospheric magnetic fields over the north pole of Venus

    NASA Astrophysics Data System (ADS)

    Zhang, T. L.; Baumjohann, W.; Russell, C. T.; Villarreal, M. N.; Luhmann, J. G.; Teh, W. L.

    2015-08-01

    Examination of Venus Express (VEX) low-altitude ionospheric magnetic field measurements during solar minimum has revealed the presence of strong magnetic fields at low altitudes over the north pole of Venus. A total of 77 events with strong magnetic fields as VEX crossed the northern polar region were identified between July 2008 and October 2009. These events all have strong horizontal fields, slowly varying with position. Using the superposed epoch method, we find that the averaged peak field is about 45 nT, which is well above the average ambient ionospheric field of 20 nT, with a full width at half maximum duration of 32 s, equivalent to a width of about 300 km. Considering the field orientation preference and spacecraft trajectory geometry, we conclude that these strong fields are found over the northern hemisphere with an occurrence frequency of more than 33% during solar minimum. They do not show a preference for any particular interplanetary magnetic field (IMF) orientation. However, they are found over the geographic pole more often when the interplanetary field is in the Venus orbital plane than when it is perpendicular to the orbital plane of Venus. The structures were found most frequently in the -E hemisphere, determined from the IMF orientation. The enhanced magnetic field is mainly quasi perpendicular to solar wind flow direction, and it is suggested that these structures form in the low-altitude collisional ionosphere where the diffusion and convection times are long.

  14. The Corporate University's Role in Managing an Epoch in Learning Organisation Innovation

    ERIC Educational Resources Information Center

    Dealtry, Richard

    2006-01-01

    Purpose: The purpose of this paper is to set the scene for some radical epochal thinking about the approach and future strategic directions in the management of organisational learning, following the author's earlier editorial theme concerning the need for exploration and innovation in organisational learning management.…

  15. Estimating Sleep from Multisensory Armband Measurements: Validity and Reliability in Teens

    PubMed Central

    Roane, Brandy M.; Van Reen, Eliza; Hart, Chantelle N.; Wing, Rena; Carskadon, Mary A.

    2015-01-01

    SUMMARY Given the recognition that sleep may influence obesity risk, there is increasing interest in measuring sleep parameters within obesity studies. The goal of the current analyses was to determine whether the SenseWear® Pro3 Armband (armband), typically used to assess physical activity, is reliable at assessing sleep parameters. We compared the armband to the AMI Motionlogger® (actigraph), a validated activity monitor for sleep assessment and to polysomnography (PSG), the gold standard for assessing sleep. Participants were twenty adolescents (mean age=15.5 years) with a mean BMI %tile of 63.7. All participants wore the armband and actigraph on their non-dominant arm while in-lab during a nocturnal PSG recording (600 minutes). Epoch-by-epoch sleep/wake data and concordance of sleep parameters were examined. No significant sleep parameter differences were found between the armband and PSG; the actigraph tended to overestimate sleep and underestimate wake compared to PSG. Both devices showed high sleep sensitivity, but lower wake detection rates. Bland-Altman plots showed large individual differences in armband sleep parameter concordance rates. The armband did well estimating sleep overall with group results more similar to PSG than the actigraph; however, the armband was less accurate at an individual level than the actigraph. PMID:26126746

  16. Estimating sleep from multisensory armband measurements: validity and reliability in teens.

    PubMed

    Roane, Brandy M; Van Reen, Eliza; Hart, Chantelle N; Wing, Rena; Carskadon, Mary A

    2015-12-01

    Given the recognition that sleep may influence obesity risk, there is increasing interest in measuring sleep parameters within obesity studies. The goal of the current analyses was to determine whether the SenseWear(®) Pro3 Armband (armband), typically used to assess physical activity, is reliable at assessing sleep parameters. The armband was compared with the AMI Motionlogger(®) (actigraph), a validated activity monitor for sleep assessment, and with polysomnography, the gold standard for assessing sleep. Participants were 20 adolescents (mean age = 15.5 years) with a mean body mass index percentile of 63.7. All participants wore the armband and actigraph on their non-dominant arm while in-lab during a nocturnal polysomnographic recording (600 min). Epoch-by-epoch sleep/wake data and concordance of sleep parameters were examined. No significant sleep parameter differences were found between the armband and polysomnography; the actigraph tended to overestimate sleep and underestimate wake compared with polysomnography. Both devices showed high sleep sensitivity, but lower wake detection rates. Bland-Altman plots showed large individual differences in armband sleep parameter concordance rates. The armband did well estimating sleep overall, with group results more similar to polysomnography than the actigraph; however, the armband was less accurate at an individual level than the actigraph. © 2015 European Sleep Research Society.

  17. Pre-movement planning processes in people with congenital mirror movements.

    PubMed

    Franz, E A; Fu, Y

    2017-10-01

    Pre-movement processes were investigated in people with Congenital mirrormovement (CMM), a rare disorder in which bilateral movement (mirroring) occurs in the upper distal extremities (primarily the hands and fingers) during intended unilateral movements. Abnormal density of ipsilateral corticospinal projections is an established hallmark of CMM. This study tested whether the Lateralised Readiness Potential (LRP), which reflects movement planning and readiness, is also abnormal in people with CMM. Twenty-eight neurologically-normal controls and 8 people with CMM were tested on a unimanual Go/No-go task while electroencephalography (EEG) was recorded to assess the LRP. No significant group differences were found in reaction time (RT). However, significantly smaller LRP amplitudes were found, on average, in the CMM group compared to Controls at central-motor (C3,C4) sites in stimulus-locked and response-locked epochs; similar group differences were also found at further frontal sites (F3,F4) during response-locked epochs. Abnormal brain activity in pre-movement processes associated with response planning and preparation is present in people with CMM. Aberrant bilateral activity during pre-movement processes is clearly implicated; whether part of the etiology of CMM, or as a mechanism of neuro-compensation, is not yet known. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

  18. Effect of Receiver Choosing on Point Positions Determination in Network RTK

    NASA Astrophysics Data System (ADS)

    Bulbul, Sercan; Inal, Cevat

    2016-04-01

    Nowadays, the developments in GNSS technique allow to determinate point positioning in real time. Initially, point positioning was determined by RTK (Real Time Kinematic) based on a reference station. But, to avoid systematic errors in this method, distance between the reference points and rover receiver must be shorter than10 km. To overcome this restriction in RTK method, the idea of setting more than one reference point had been suggested and, CORS (Continuously Operations Reference Systems) was put into practice. Today, countries like ABD, Germany, Japan etc. have set CORS network. CORS-TR network which has 146 reference points has also been established in 2009 in Turkey. In CORS-TR network, active CORS approach was adopted. In Turkey, CORS-TR reference stations covering whole country are interconnected and, the positions of these stations and atmospheric corrections are continuously calculated. In this study, in a selected point, RTK measurements based on CORS-TR, were made with different receivers (JAVAD TRIUMPH-1, TOPCON Hiper V, MAGELLAN PRoMark 500, PENTAX SMT888-3G, SATLAB SL-600) and with different correction techniques (VRS, FKP, MAC). In the measurements, epoch interval was taken as 5 seconds and measurement time as 1 hour. According to each receiver and each correction technique, means and differences between maximum and minimum values of measured coordinates, root mean squares in the directions of coordinate axis and 2D and 3D positioning precisions were calculated, the results were evaluated by statistical methods and the obtained graphics were interpreted. After evaluation of the measurements and calculations, for each receiver and each correction technique; the coordinate differences between maximum and minimum values were measured to be less than 8 cm, root mean squares in coordinate axis directions less than ±1.5 cm, 2D point positioning precisions less than ±1.5 cm and 3D point positioning precisions less than ±1.5 cm. In the measurement point, it has been concluded that VRS correction technique is generally better than other corrections techniques.

  19. Measures of sleep and cardiac functioning during sleep using a multi-sensory commercially-available wristband in adolescents.

    PubMed

    de Zambotti, Massimiliano; Baker, Fiona C; Willoughby, Adrian R; Godino, Job G; Wing, David; Patrick, Kevin; Colrain, Ian M

    2016-05-01

    To validate measures of sleep and heart rate (HR) during sleep generated by a commercially-available activity tracker against those derived from polysomnography (PSG) in healthy adolescents. Sleep data were concurrently recorded using FitbitChargeHR™ and PSG, including electrocardiography (ECG), during an overnight laboratory sleep recording in 32 healthy adolescents (15 females; age, mean±SD: 17.3±2.5years). Sleep and HR measures were compared between FitbitChargeHR™ and PSG using paired t-tests and Bland-Altman plots. Epoch-by-epoch analysis showed that FitbitChargeHR™ had high overall accuracy (91%), high sensitivity (97%) in detecting sleep, and poor specificity (42%) in detecting wake on a min-to-min basis. On average, FitbitChargeHR™ significantly but negligibly overestimated total sleep time by 8min and sleep efficiency by 1.8%, and underestimated wake after sleep onset by 5.6min (p<0.05). Within FitbitChargeHR™ epochs of sleep, the average HR was 59.3±7.5bpm, which was significantly but negligibly lower than that calculated from ECG (60.2±7.6bpm, p<0.001), with no change in mean discrepancies throughout the night. FitbitChargeHR™ showed good agreement with PSG and ECG in measuring sleep and HR during sleep, supporting its use in assessing sleep and cardiac function in healthy adolescents. Further validation is needed to assess its reliability over prolonged periods of time in ecological settings and in clinical populations. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Measures of Sleep and Cardiac Functioning During Sleep Using a Multi-Sensory Commercially–Available Wristband in Adolescents

    PubMed Central

    de Zambotti, Massimiliano; Baker, Fiona C.; Willoughby, Adrian R.; Godino, Job G.; Wing, David; Patrick, Kevin; Colrain, Ian M.

    2016-01-01

    To validate measures of sleep and heart rate (HR) during sleep generated by a commercially-available activity tracker against those derived from polysomnography (PSG) in healthy adolescents. Sleep data were concurrently recorded using FitbitChargeHR™ and PSG, including electrocardiography (ECG), during an overnight laboratory sleep recording in 32 healthy adolescents (15 females; Age, mean±SD: 17.3±2.5 years). Sleep and HR measures were compared between FitbitChargeHR™ and PSG using paired t-tests and Bland-Altman plots. Epoch-by-epoch analysis showed that FitbitChargeHR™ had high overall accuracy (91%), high sensitivity (97%) in detecting sleep, and poor specificity (42%) in detecting wake on a min-to-min basis. On average, FitbitChargeHR™ significantly but negligibly overestimated total sleep time by 8min and sleep efficiency by 1.8%, and underestimated wake after sleep onset by 5.6min (p<0.05). Within FitbitChargeHR™ epochs of sleep, the average HR was 59.3±7.5 bpm, which was significantly but negligibly lower than that calculated from ECG (60.2±7.6 bpm, p<0.001), with no change in mean discrepancies throughout the night. FitbitChargeHR™ showed good agreement with PSG and ECG in measuring sleep and HR during sleep, supporting its use in assessing sleep and cardiac function in healthy adolescents. Further validation is needed to assess its reliability over prolonged periods of time in ecological settings and in clinical populations. PMID:26969518

  1. Assessing complexity of skin blood flow oscillations in response to locally applied heating and pressure in rats: Implications for pressure ulcer risk

    NASA Astrophysics Data System (ADS)

    Liao, Fuyuan; O'Brien, William D.; Jan, Yih-Kuen

    2013-10-01

    The objective of this study was to investigate the effects of local heating on the complexity of skin blood flow oscillations (BFO) under prolonged surface pressure in rats. Eleven Sprague-Dawley rats were studied: 7 rats underwent surface pressure with local heating (△t=10 °C) and 4 rats underwent pressure without heating. A pressure of 700 mmHg was applied to the right trochanter area of rats for 3 h. Skin blood flow was measured using laser Doppler flowmetry. The loading period was divided into nonoverlapping 30 min epochs. For each epoch, multifractal detrended fluctuation analysis (MDFA) was utilized to compute DFA coefficients and complexity of endothelial related metabolic, neurogenic, and myogenic frequencies of BFO. The results showed that under surface pressure, local heating led to a significant decrease in DFA coefficients of myogenic frequency during the initial epoch of loading period, a sustained decrease in complexity of myogenic frequency, and a significantly higher degree of complexity of metabolic frequency during the later phase of loading period. Surrogate tests showed that the reduction in complexity of myogenic frequency was associated with a loss of nonlinearity whereas increased complexity of metabolic frequency was associated with enhanced nonlinearity. Our results indicate that increased metabolic activity and decreased myogenic response due to local heating manifest themselves not only in magnitudes of metabolic and myogenic frequencies but also in their structural complexity. This study demonstrates the feasibility of using complexity analysis of BFO to monitor the ischemic status of weight-bearing skin and risk of pressure ulcers.

  2. Quasar Feedback at the Peak of Galaxy Formation Epoch

    NASA Astrophysics Data System (ADS)

    Liu, Guilin; Zakamska, Nadia L.; Strauss, Michael A.; Greene, Jenny E.; Alexandroff, Rachael

    2013-02-01

    The correlations between properties of supermassive black holes and stellar spheroids in galaxies imply a physical connection between these two components in spite of their vastly different masses and physical scales. Using Gemini GMOS IFU, we demonstrated that powerful ionized gas winds are a ubiquitous feature in luminous radio-quiet obscured z 0.5 quasars. We now plan to extend this discovery to the era of peak galaxy formation and quasar activity - to the epoch when feedback was most prominent and the galaxy vs. black hole correlations were established. We propose a GMOS IFU survey to map the spatial distribution and the kinematics of Ly(alpha) and N sc v 1240Å emission around 5 obscured quasars at z=3-3.4. We will use Ly(alpha) observations to directly probe the effects of ionizing radiation of obscured quasars on their large-scale environments and N sc v observations to look for signatures of unbound quasar-driven outflows. We will observe in the g-band on sub-galactic and galaxy- wide scales (spatial resolution 3-6 kpc, field of view 40times50 kpc^2 at z=3). Obscured quasars likely constitute the majority of the quasar population and may represent the relatively early enshrouded phase of black hole growth; thus, luminous obscured quasars are the most likely sites of quasar ionization- and wind-feedback, as we found at low redshifts. Our proposed GMOS observations will provide a definitive probe of the effects of quasars on their galaxy-wide and large-scale environments close to the peak of galaxy formation epoch.

  3. Detection of magnetic field in the B2 star ρ Ophiuchi A with ESO FORS2

    NASA Astrophysics Data System (ADS)

    Pillitteri, I.; Fossati, L.; Castro Rodriguez, N.; Oskinova, L.; Wolk, S. J.

    2018-02-01

    Circumstantial evidence suggests that magnetism and enhanced X-ray emission are likely correlated in early B-type stars: similar fractions of them ( 10%) are strong and hard X-ray sources and possess strong magnetic fields. It is also known that some B-type stars have spots on their surface. Yet up to now no X-ray activity associated with spots on early-type stars was detected. In this Letter we report the detection of a magnetic field on the B2V star ρ Oph A. Previously, we assessed that the X-ray activity of this star is associated with a surface spot, herewith we establish its magnetic origin. We analyze spectra of ρ Oph A obtained with the FORS2 spectrograph at ESO Very Large Telescope (VLT) at two epochs, and detect a longitudinal component of the magnetic field of the order of 500 G in one of the datasets. The detection of the magnetic field only at one epoch can be explained by stellar rotation which is also invoked to explain observed periodic X-ray activity. From archival HARPS ESO VLT high resolution spectra we derived the fundamental stellar parameters of ρ Oph A and further constrained its age. We conclude that ρ Oph A provides strong evidence for the presence of active X-ray emitting regions on young magnetized early type stars. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 099.D-0067(A) and 078.C-0403(A).

  4. An Intense Terminal Epoch of Widespread Fluvial Activity on Early Mars: 2. Increased Runoff and Paleolake Development

    NASA Technical Reports Server (NTRS)

    Rossman III, Irwin P.; Howard, Alan D.; Craddock, Robert A.; Moore, Jeffrey M.

    2005-01-01

    To explain the much higher denudation rates and valley network development on early Mars (more than approximately 3.6 Gyr ago), most investigators have invoked either steady state warm/wet (Earthlike) or cold/dry (modern Mars) end-member paleoclimates. Here we discuss evidence that highland gradation was prolonged, but generally slow and possibly ephemeral during the Noachian Period, and that the immature valley networks entrenched during a brief terminal epoch of more erosive fluvial activity in the late Noachian to early Hesperian. Observational support for this interpretation includes (1) late-stage breaching of some enclosed basins that had previously been extensively modified, but only by internal erosion and deposition; (2) deposition of pristine deltas and fans during a late stage of contributing valley entrenchment; (3) a brief, erosive response to base level decline (which was imparted as fretted terrain developed by a suite of processes unrelated to surface runoff) in fluvial valleys that crosscut the highland-lowland boundary scarp; and (4) width/contributing area relationships of interior channels within valley networks, which record significant late-stage runoff production with no evidence of recovery to lower-flow conditions. This erosion appears to have ended abruptly, as depositional landforms generally were not entrenched with declining base level in crater lakes. A possible planetwide synchronicity and common cause to the late-stage fluvial activity are possible but remain uncertain. This increased activity of valley networks is offered as a possible explanation for diverse features of highland drainage basins, which were previously cited to support competing warm, wet and cold, dry paleoclimate scenarios.

  5. Evidence for possible relation between local irregularities in the horizondal deformation field and microseismic activity of the Mygdonian basin(Northern Greece)

    NASA Astrophysics Data System (ADS)

    Contadakis, M. E.; Leventakis, G.-A. N.

    1992-12-01

    Geodetic methods have been proved very useful tools for the detection and monitoring of the earth crustal deformation. Using the repeated measurements in the decade 1979-1990 of the 16-point trigonometric network, located in the seismic active area of the lake Volvi in Northern Greece, a continuous strain field was determined for the area and for each epoch of the corresponding surveys. The dominant characteristic of the deformation field of the area relates, in a way, to the system of the surface faults, which appeared after the string earthquake of June 21, 1978. In addition, there is local as well as time variation of the strain field which is well correlated with the microseismic activity of the area. That is, although there is a general tendency of a N-S horizontal extension in accordance with the direction of the stress field of the area, regions of contraction appear in places where microseismic activity has taken place before the epochs of the respective survey. A few shocks in these region, for which reliable fault plane solutions could be defined by Scordilis on 1985,show focal mechanisms conformable to the geodetic results. Seismicity and fault plane solutions, based on a micro-earthquake study of the region during March and April of 1984 by Hatzfeld et al. with the help of a temporary network of 29 portable stations shows a rather complex pattern. The proposed model for the formation and the evolution of a complex graben system conform qualitatively to the geodetic results

  6. The Reel Deal: Interpreting HST Multi-Epoch Movies of YSO Jets.

    NASA Astrophysics Data System (ADS)

    Frank, Adam

    2010-09-01

    The goal of this proposal is to bring the theoretical interpretation of Young Stellar Object jets and their environments to a new level of realism. We propose to build on the results of a successful Cycle 16 observing proposal that has obtained 3rd epoch images of HH jets. We will use Adaptive Mesh Refinement MHD simulations {developed by our team} to carry forward a detailed program of modeling and interpretation of the time-dependent behavior revealed in the new, extended multi-epoch data set. Only with the third epoch observations can we explore forces: i.e. accelerations, decelerations and structural changes to develop an accurate understanding of physical processes occurring in hypersonic, magnetized jet flows. Our studies will allow us to characterize the jets and, therefore, make the crucial link with jet central engines. We note an innovative feature of our project is its link with laboratory astrophysical experiments of jets. Our analysis of the observations will be used to determine future laboratory experiments which will explore A?clumpyA? jet propagation issues.

  7. THE TIME EVOLUTION OF HH 1 FROM FOUR EPOCHS OF HST IMAGES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raga, A. C.; Esquivel, A.; Reipurth, B.

    We present an analysis of four epochs of Hα and [S ii] λλ 6716/6731 Hubble Space Telescope (HST) images of HH 1. For determining proper motions, we explore a new method based on the analysis of spatially degraded images obtained convolving the images with wavelet functions of chosen widths. With this procedure, we are able to generate maps of proper motion velocities along and across the outflow axis, as well as (angularly integrated) proper motion velocity distributions. From the four available epochs, we find the time evolution of the velocities, intensities, and spatial distribution of the line emission. We find that overmore » the last two decades HH 1 shows a clear acceleration. Also, the Hα and [S ii] intensities first dropped and then recovered in the more recent (2014) images. Finally, we show a comparison between the two available HST epochs of [O iii] λ 5007 (1994 and 2014), in which we see a clear drop in the value of the [O iii]/Hα ratio.« less

  8. Outgassing History and Escape of the Martian Atmosphere and Water Inventory

    NASA Astrophysics Data System (ADS)

    Lammer, Helmut; Chassefière, Eric; Karatekin, Özgür; Morschhauser, Achim; Niles, Paul B.; Mousis, Olivier; Odert, Petra; Möstl, Ute V.; Breuer, Doris; Dehant, Véronique; Grott, Matthias; Gröller, Hannes; Hauber, Ernst; Pham, Lê Binh San

    2013-01-01

    The evolution and escape of the martian atmosphere and the planet's water inventory can be separated into an early and late evolutionary epoch. The first epoch started from the planet's origin and lasted ˜500 Myr. Because of the high EUV flux of the young Sun and Mars' low gravity it was accompanied by hydrodynamic blow-off of hydrogen and strong thermal escape rates of dragged heavier species such as O and C atoms. After the main part of the protoatmosphere was lost, impact-related volatiles and mantle outgassing may have resulted in accumulation of a secondary CO2 atmosphere of a few tens to a few hundred mbar around ˜4-4.3 Gyr ago. The evolution of the atmospheric surface pressure and water inventory of such a secondary atmosphere during the second epoch which lasted from the end of the Noachian until today was most likely determined by a complex interplay of various nonthermal atmospheric escape processes, impacts, carbonate precipitation, and serpentinization during the Hesperian and Amazonian epochs which led to the present day surface pressure.

  9. Epoch-based Entropy for Early Screening of Alzheimer's Disease.

    PubMed

    Houmani, N; Dreyfus, G; Vialatte, F B

    2015-12-01

    In this paper, we introduce a novel entropy measure, termed epoch-based entropy. This measure quantifies disorder of EEG signals both at the time level and spatial level, using local density estimation by a Hidden Markov Model on inter-channel stationary epochs. The investigation is led on a multi-centric EEG database recorded from patients at an early stage of Alzheimer's disease (AD) and age-matched healthy subjects. We investigate the classification performances of this method, its robustness to noise, and its sensitivity to sampling frequency and to variations of hyperparameters. The measure is compared to two alternative complexity measures, Shannon's entropy and correlation dimension. The classification accuracies for the discrimination of AD patients from healthy subjects were estimated using a linear classifier designed on a development dataset, and subsequently tested on an independent test set. Epoch-based entropy reached a classification accuracy of 83% on the test dataset (specificity = 83.3%, sensitivity = 82.3%), outperforming the two other complexity measures. Furthermore, it was shown to be more stable to hyperparameter variations, and less sensitive to noise and sampling frequency disturbances than the other two complexity measures.

  10. Simultaneously constraining the astrophysics of reionization and the epoch of heating with 21CMMC

    NASA Astrophysics Data System (ADS)

    Greig, Bradley; Mesinger, Andrei

    2017-12-01

    The cosmic 21 cm signal is set to revolutionize our understanding of the early Universe, allowing us to probe the 3D temperature and ionization structure of the intergalactic medium (IGM). It will open a window on to the unseen first galaxies, showing us how their UV and X-ray photons drove the cosmic milestones of the epoch of reionization (EoR) and epoch of heating (EoH). To facilitate parameter inference from the 21 cm signal, we previously developed 21CMMC: a Monte Carlo Markov Chain sampler of 3D EoR simulations. Here, we extend 21CMMC to include simultaneous modelling of the EoH, resulting in a complete Bayesian inference framework for the astrophysics dominating the observable epochs of the cosmic 21 cm signal. We demonstrate that second-generation interferometers, the Hydrogen Epoch of Reionization Array and Square Kilometre Array will be able to constrain ionizing and X-ray source properties of the first galaxies with a fractional precision of the order of ∼1-10 per cent (1σ). The ionization history of the Universe can be constrained to within a few percent. Using our extended framework, we quantify the bias in EoR parameter recovery incurred by the common simplification of a saturated spin temperature in the IGM. Depending on the extent of overlap between the EoR and the EoH, the recovered astrophysical parameters can be biased by ∼3σ-10σ.

  11. Causal Conceptions in Social Explanation and Moral Evaluation: A Historical Tour.

    PubMed

    Alicke, Mark D; Mandel, David R; Hilton, Denis J; Gerstenberg, Tobias; Lagnado, David A

    2015-11-01

    Understanding the causes of human behavior is essential for advancing one's interests and for coordinating social relations. The scientific study of how people arrive at such understandings or explanations has unfolded in four distinguishable epochs in psychology, each characterized by a different metaphor that researchers have used to represent how people think as they attribute causality and blame to other individuals. The first epoch was guided by an "intuitive scientist" metaphor, which emphasized whether observers perceived behavior to be caused by the unique tendencies of the actor or by common reactions to the requirements of the situation. This metaphor was displaced in the second epoch by an "intuitive lawyer" depiction that focused on the need to hold people responsible for their misdeeds. The third epoch was dominated by theories of counterfactual thinking, which conveyed a "person as reconstructor" approach that emphasized the antecedents and consequences of imagining alternatives to events, especially harmful ones. With the current upsurge in moral psychology, the fourth epoch emphasizes the moral-evaluative aspect of causal judgment, reflected in a "person as moralist" metaphor. By tracing the progression from the person-environment distinction in early attribution theories to present concerns with moral judgment, our goal is to clarify how causal constructs have been used, how they relate to one another, and what unique attributional problems each addresses. © Her Majesty the Queen in Right of Canada, as represented by Defence Research and Development Canada 2015.

  12. On the Hipparcos Link to the ICRF derived from VLA and MERLIN radio astrometry

    NASA Astrophysics Data System (ADS)

    Hering, R.; Walter, H. G.

    2007-06-01

    Positions and proper motions obtained from observations by the very large array (VLA) and the multi-element radio-linked interferometer network (MERLIN) are used to establish the link of the Hipparcos Celestial Reference Frame (HCRF) to the International Celestial Reference Frame (ICRF). The VLA and MERLIN data are apparently the latest ones published in the literature. Their mean epoch at around 2001 is about 10 years after the epoch of the Hipparcos catalogue and, therefore, the data are considered suitable to check the Hipparcos link established at epoch 1991.25. The parameters of the link, i.e., the angles of frame orientation and the angular rates of frame rotation, are estimated by fitting these parameters to the differences of the optical and radio positions and proper motions of stars common to the Hipparcos catalogue and the VLA and MERLIN data. Both the estimates of the angles of orientation and the angular rates of rotation show nearly consistent but insignificant results for all samples of stars treated. We conclude that not only the size of the samples of 9 15 stars is too small, but also that the accuracy of the radio positions and, above all, of the radio proper motions is insufficient, the latter being based on early-epoch star positions of low accuracy. The present observational data at epoch 2001 suggest that maintenance of the Hipparcos frame is not feasible at this stage.

  13. Correlations between gait speed, 6-minute walk distance, physical activity, and self-efficacy in patients with severe chronic lung disease.

    PubMed

    DePew, Zachary S; Karpman, Craig; Novotny, Paul J; Benzo, Roberto P

    2013-12-01

    Four-meter gait speed (4MGS) has been associated with functional capacity and overall mortality in elderly patients, and may easily be translated to daily practice. We evaluated the association of 4MGS with meaningful outcomes. In 70 subjects we conducted the 4MGS, 6-min walk test (6MWT), objectively measured physical activity, and assessed dyspnea, quality of life, and self-efficacy for walking and routine physical activity. 4MGS was measured in 3 separate time epochs during the 6MWT, to explore 4MGS variability. Diagnoses included COPD (51.4%), interstitial lung disease (38.6%), and other pulmonary conditions (10%). The mean ± SD values were: 4MGS 0.85 ± 0.21 m/s, 6-min walk distance (6MWD) 305 ± 115 m, and physical activity level 1.28 ± 0.17, which is consistent with severe physical inactivity. The gait speeds within the time epochs 1-2, 3-4, and 5-6 min during the 6MWT were not significantly different: 1.01 ± 0.29 m/s, 0.98 ± 0.31 m/s, and 1.00 ± 0.31 m/s, respectively. 4MGS had a significant correlation with 6MWD (r = 0.70, P < .001). 6MWD was the dominant variable for predicting 4MGS. Other significant predictors of 4MGS included dyspnea, self-efficacy, quality of life, and objectively measured physical activity. 4MGS is significantly and independently associated with 6MWD, and may serve as a reasonable simple surrogate for 6MWD in subjects with chronic lung disease. Gait speed was remarkably stable throughout the 6MWT, which supports the validity of an abbreviated walk test such as 4MGS.

  14. Can sleep quality and wellbeing be improved by changing the indoor lighting in the homes of healthy, elderly citizens?

    PubMed Central

    Sander, Birgit; Markvart, Jakob; Kessel, Line; Argyraki, Aikaterini; Johnsen, Kjeld

    2015-01-01

    The study investigated the effect of bright blue-enriched versus blue-suppressed indoor light on sleep and wellbeing of healthy participants over 65 years. Twenty-nine participants in 20 private houses in a uniform settlement in Copenhagen were exposed to two light epochs of 3 weeks with blue-enriched (280 lux) and 3 weeks blue-suppressed (240 lux) indoor light or vice versa from 8 to 13 pm in a randomized cross-over design. The first light epoch was in October, the second in November and the two light epochs were separated by one week. Participants were examined at baseline and at the end of each light epoch. The experimental indoor light was well tolerated by the majority of the participants. Sleep duration was 7.44 (95% CI 7.14–7.74) hours during blue-enriched conditions and 7.31 (95% CI 7.01–7.62) hours during blue-suppressed conditions (p = 0.289). Neither rest hours, chromatic pupillometry, nor saliva melatonin profile showed significant changes between blue-enriched and blue-suppressed epochs. Baseline Pittsburgh Sleep Quality Index (PSQI) was significantly worse in females; 7.62 (95% CI 5.13–10.0) versus 4.06 (95% CI 2.64–5.49) in males, p = 0.009. For females, PSQI improved significantly during blue-enriched light exposure (p = 0.007); no significant changes were found for males. The subjective grading of indoor light quality doubled from participants habitual indoor light to the bright experimental light, while it was stable between light epochs, although there were clear differences between blue-enriched and blue-suppressed electrical light conditions imposed. Even though the study was carried out in the late autumn at northern latitude, the only significant difference in Actiwatch-measured total blue light exposure was from 8 to 9 am, because contributions from blue-enriched, bright indoor light were superseded by contributions from daylight. PMID:26181467

  15. Sensitivity of quantitative EEG for seizure identification in the intensive care unit.

    PubMed

    Haider, Hiba A; Esteller, Rosana; Hahn, Cecil D; Westover, M Brandon; Halford, Jonathan J; Lee, Jong W; Shafi, Mouhsin M; Gaspard, Nicolas; Herman, Susan T; Gerard, Elizabeth E; Hirsch, Lawrence J; Ehrenberg, Joshua A; LaRoche, Suzette M

    2016-08-30

    To evaluate the sensitivity of quantitative EEG (QEEG) for electrographic seizure identification in the intensive care unit (ICU). Six-hour EEG epochs chosen from 15 patients underwent transformation into QEEG displays. Each epoch was reviewed in 3 formats: raw EEG, QEEG + raw, and QEEG-only. Epochs were also analyzed by a proprietary seizure detection algorithm. Nine neurophysiologists reviewed raw EEGs to identify seizures to serve as the gold standard. Nine other neurophysiologists with experience in QEEG evaluated the epochs in QEEG formats, with and without concomitant raw EEG. Sensitivity and false-positive rates (FPRs) for seizure identification were calculated and median review time assessed. Mean sensitivity for seizure identification ranged from 51% to 67% for QEEG-only and 63%-68% for QEEG + raw. FPRs averaged 1/h for QEEG-only and 0.5/h for QEEG + raw. Mean sensitivity of seizure probability software was 26.2%-26.7%, with FPR of 0.07/h. Epochs with the highest sensitivities contained frequent, intermittent seizures. Lower sensitivities were seen with slow-frequency, low-amplitude seizures and epochs with rhythmic or periodic patterns. Median review times were shorter for QEEG (6 minutes) and QEEG + raw analysis (14.5 minutes) vs raw EEG (19 minutes; p = 0.00003). A panel of QEEG trends can be used by experts to shorten EEG review time for seizure identification with reasonable sensitivity and low FPRs. The prevalence of false detections confirms that raw EEG review must be used in conjunction with QEEG. Studies are needed to identify optimal QEEG trend configurations and the utility of QEEG as a screening tool for non-EEG personnel. This study provides Class II evidence that QEEG + raw interpreted by experts identifies seizures in patients in the ICU with a sensitivity of 63%-68% and FPR of 0.5 seizures per hour. © 2016 American Academy of Neurology.

  16. Minimizing Interrater Variability in Staging Sleep by Use of Computer-Derived Features

    PubMed Central

    Younes, Magdy; Hanly, Patrick J.

    2016-01-01

    Study Objectives: Inter-scorer variability in sleep staging of polysomnograms (PSGs) results primarily from difficulty in determining whether: (1) an electroencephalogram pattern of wakefulness spans > 15 sec in transitional epochs, (2) spindles or K complexes are present, and (3) duration of delta waves exceeds 6 sec in a 30-sec epoch. We hypothesized that providing digitally derived information about these variables to PSG scorers may reduce inter-scorer variability. Methods: Fifty-six PSGs were scored (five-stage) by two experienced technologists, (first manual, M1). Months later, the technologists edited their own scoring (second manual, M2). PSGs were then scored with an automatic system and the same two technologists and an additional experienced technologist edited them, epoch-by-epoch (Edited-Auto). This resulted in seven manual scores for each PSG. The two M2 scores were then independently modified using digitally obtained values for sleep depth and delta duration and digitally identified spindles and K complexes. Results: Percent agreement between scorers in M2 was 78.9 ± 9.0% before modification and 96.5 ± 2.6% after. Errors of this approach were defined as a change in a manual score to a stage that was not assigned by any scorer during the seven manual scoring sessions. Total errors averaged 7.1 ± 3.7% and 6.9 ± 3.8% of epochs for scorers 1 and 2, respectively, and there was excellent agreement between the modified score and the initial manual score of each technologist. Conclusions: Providing digitally obtained information about sleep depth, delta duration, spindles and K complexes during manual scoring can greatly reduce interrater variability in sleep staging by eliminating the guesswork in scoring epochs with equivocal features. Citation: Younes M, Hanly PJ. Minimizing interrater variability in staging sleep by use of computer-derived features. J Clin Sleep Med 2016;12(10):1347–1356. PMID:27448418

  17. Long-Term Neurodevelopmental Outcomes of Premature Infants in Singapore.

    PubMed

    Teo, Charmaine M; Poon, Woei Bing; Ho, Selina Ky

    2018-02-01

    Neonatal care advances have resulted in improved survival but have raised concerns of increase in neurodevelopmental impairment. This study looked at long-term neurodevelopmental outcomes at ages 5 and 8 years of very low birthweight infants born in the 2000s as compared to the 1990s. Neurodevelopmental assessment at 2 years old was compared to that at 5 and 8 years to determine if assessment at 2 years was predictive of later outcomes. A retrospective cohort study of consecutive infants with birthweight less than 1250 grams admitted to a tertiary centre in Singapore between January 1994 to December 1995 (Epoch I) and January 2004 to December 2005 (Epoch II) were included. Neurodevelopmental impairment was defined as having intelligence quotient (IQ) of less than 70, cerebral palsy, legal blindness, or hearing impairment requiring hearing aids. Mean gestational age was lower for Epoch II compared to Epoch I (28.1 ± 2.5 vs 29.4 ± 2.7 weeks, P = 0.004). Death or neurodevelopmental impairment rates did not differ (24.3% and 17.1% at 5 years old, P = 0.398; 29.1% and 25.0% at 8 years old, P = 0.709). There was improvement in visual impairment rate at 8 years in Epoch II (10.7% vs 34.0%, P = 0.024). Mean IQ was better in Epoch II (109 and 107 vs 97 and 99 at 5 [ P = 0.001] and 8 years [ P = 0.047], respectively). All infants with no neurodevelopmental impairment at 2 years remained without impairment later on. Over a decade, neurodevelopmental outcomes did not worsen despite lower mean gestational age. Long- term improvement in IQ scores and a reduction in visual impairment rates were seen. Our data suggests that children without neurodevelopmental impairment at 2 years are without impairment later on; therefore, they may need only developmental monitoring with targeted assessments instead of routine formal IQ assessments.

  18. End-of-treatment and serial PET imaging in primary mediastinal B-cell lymphoma following dose-adjusted-EPOCH-R: A paradigm shift in clinical decision making.

    PubMed

    Melani, Christopher; Advani, Ranjana; Roschewski, Mark; Walters, Kelsey M; Chen, Clara C; Baratto, Lucia; Ahlman, Mark A; Miljkovic, Milos D; Steinberg, Seth M; Lam, Jessica; Shovlin, Margaret; Dunleavy, Kieron; Pittaluga, Stefania; Jaffe, Elaine S; Wilson, Wyndham H

    2018-05-10

    Dose-adjusted-EPOCH-R obviates the need for radiotherapy in most patients with primary mediastinal B-cell lymphoma. End-of-treatment PET, however, does not accurately identify patients at risk of treatment failure, thereby confounding clinical decision making. To define the role of PET in primary mediastinal B-cell lymphoma following dose-adjusted-EPOCH-R, we extended enrollment and follow-up on our published phase II trial and independent series. Ninety-three patients received dose-adjusted-EPOCH-R without radiotherapy. End-of-treatment PET was performed in 80 patients, of whom 57 received 144 serial scans. One nuclear medicine physician from each institution blindly reviewed all scans from their respective institution. End-of-treatment PET was negative (Deauville 1-3) in 55 (69%) patients with one treatment failure (8-year event-free and overall survival of 96.0% and 97.7%). Among 25 (31%) patients with a positive (Deauville 4-5) end-of-treatment PET, there were 5 (20%) treatment failures (8-year event-free and overall survival of 71.1% and 84.3%). Linear regression analysis of serial scans showed a significant decrease in SUVmax in positive end-of-treatment PET non-progressors compared to an increase in treatment failures. Among 6 treatment failures, the median end-of-treatment SUVmax was 15.4 (range, 1.9-21.3) and 4 achieved long-term remission with salvage therapy. Virtually all patients with a negative end-of-treatment PET following dose-adjusted-EPOCH-R achieved durable remissions and should not receive radiotherapy. Among patients with a positive end-of-treatment PET, only 5/25 (20%) had treatment-failure. Serial PET imaging distinguished end-of-treatment PET positive patients without treatment failure, thereby reducing unnecessary radiotherapy by 80%, and should be considered in all patients with an initial positive PET following dose-adjusted-EPOCH-R (NCT00001337). Copyright © 2018, Ferrata Storti Foundation.

  19. Assessing REM Sleep in Mice Using Video Data

    PubMed Central

    McShane, Blakeley B.; Galante, Raymond J.; Biber, Michael; Jensen, Shane T.; Wyner, Abraham J.; Pack, Allan I.

    2012-01-01

    Study Objectives: Assessment of sleep and its substages in mice currently requires implantation of chronic electrodes for measurement of electroencephalogram (EEG) and electromyogram (EMG). This is not ideal for high-throughput screening. To address this deficiency, we present a novel method based on digital video analysis. This methodology extends previous approaches that estimate sleep and wakefulness without EEG/EMG in order to now discriminate rapid eye movement (REM) from non-REM (NREM) sleep. Design: Studies were conducted in 8 male C57BL/6J mice. EEG/EMG were recorded for 24 hours and manually scored in 10-second epochs. Mouse behavior was continuously recorded by digital video at 10 frames/second. Six variables were extracted from the video for each 10-second epoch (i.e., intraepoch mean of velocity, aspect ratio, and area of the mouse and intraepoch standard deviation of the same variables) and used as inputs for our model. Measurements and Results: We focus on estimating features of REM (i.e., time spent in REM, number of bouts, and median bout length) as well as time spent in NREM and WAKE. We also consider the model's epoch-by-epoch scoring performance relative to several alternative approaches. Our model provides good estimates of these features across the day both when averaged across mice and in individual mice, but the epoch-by-epoch agreement is not as good. Conclusions: There are subtle changes in the area and shape (i.e., aspect ratio) of the mouse as it transitions from NREM to REM, likely due to the atonia of REM, thus allowing our methodology to discriminate these two states. Although REM is relatively rare, our methodology can detect it and assess the amount of REM sleep. Citation: McShane BB; Galante RJ; Biber M; Jensen ST; Wyner AJ; Pack AI. Assessing REM sleep in mice using video data. SLEEP 2012;35(3):433-442. PMID:22379250

  20. A description of communication patterns during CPR in ICU.

    PubMed

    Taylor, Katherine L; Ferri, Susan; Yavorska, Tatyana; Everett, Tobias; Parshuram, Christopher

    2014-10-01

    Deficiencies in communication in health care are a common source of medical error. Preferred communication patterns are a component of resuscitation teaching. We audio-recorded resuscitations in a mixed paediatric medical and surgical ICU to describe communication. In the intensive care unit, resuscitation events were prospectively audio-recorded by two trained observers (using handheld recorders). Recordings were transcribed and anonymised within 24h. We grouped utterances regarding the same subject matter from beginning (irrespective of response) as a communication epoch. For each epoch, we describe the initiator, audience and content of message. Teamwork behaviours were described using Anesthesia Nontechnical Skills framework (ANTS), a behavioural marker system for crisis-resource management. Consent rates from staff were 139/140 (99%) and parents were 67/92 (73%). We analysed 36min 57s of audio dialogue from 4 cardiac arrest events in 363h of prospective screening. There were 180 communication epochs (1 every 12s): 100 (56%) from the team-leader and 80 (44%) from non-team-leader(s). Team-leader epochs were to give or confirm orders or assert authority (61%), clarify patient history (14%) and provide clinical updates (25%). Non-team-leader epochs were more often directed to the team (65%) than the team-leader (35%). Audio-recordings provided information for 80% of the ANTS component elements with scores of 2-4. Communication epochs were frequent, most from the team-leader. We identified an 'outer loop' of communication between team members not including the team-leader, responsible for 44% of all communication events. We discuss difficulties in this research methodology. Future work includes exploring the process of the 'outer loop' by resuscitation team members to evaluate the optimal balance between single leader and team suggestions, the content of the outer loop discussions and in-event communication strategies to improve outcomes. Crown Copyright © 2014. Published by Elsevier Ireland Ltd. All rights reserved.

  1. HST Archival Imaging of the Light Echoes of SN 1987A

    NASA Astrophysics Data System (ADS)

    Lawrence, S. S.; Hayon, M.; Sugerman, B. E. K.; Crotts, A. P. S.

    2002-12-01

    We have undertaken a search for light echo signals from Supernova 1987A that have been serendipitously recorded in images taken near the 30 Doradus region of the Large Magellanic Cloud by HST. We used the MAST interface to create a database of the 1282 WF/PC, WFPC2 and STIS images taken within 15 arcminutes of the supernova, between 1992 April and 2002 June. These 1282 images are grouped into 125 distinct epochs and pointings, with each epoch containing between 1 and 42 separate exposures. Sorting this database with various programs, aided by the STScI Visual Target Tuner, we have identified 63 pairs of WFPC2 imaging epochs that are not centered on the supernova but that have a significant amount of spatial overlap between their fields of view. These image data were downloaded from the public archive, cleaned of cosmic rays, and blinked to search for light echoes at radii larger than 2 arcminutes from the supernova. Our search to date has focused on those pairs of epochs with the largest degree of overlap. Of 16 pairs of epochs scanned to date, we have detected 3 strong light echoes and one faint, tentative echo signal. We will present direct and difference images of these and any further echoes, as well as the 3-D geometric, photometric and color properties of the echoing dust structures. In addition, a set of 20 epochs of WF/PC and WFPC2 imaging centered on SN 1987A remain to be searched for echoes within 2 arcminutes of the supernova. We will discuss our plans to integrate the high spatial-resolution HST snapshots of the echoes with our extensive, well-time-sampled, ground-based imaging data. We gratefully acknowledge the support of this undergraduate research project through an HST Archival Research Grant (HST-AR-09209.01-A).

  2. Validation of Photoplethysmography-Based Sleep Staging Compared With Polysomnography in Healthy Middle-Aged Adults.

    PubMed

    Fonseca, Pedro; Weysen, Tim; Goelema, Maaike S; Møst, Els I S; Radha, Mustafa; Lunsingh Scheurleer, Charlotte; van den Heuvel, Leonie; Aarts, Ronald M

    2017-07-01

    To compare the accuracy of automatic sleep staging based on heart rate variability measured from photoplethysmography (PPG) combined with body movements measured with an accelerometer, with polysomnography (PSG) and actigraphy. Using wrist-worn PPG to analyze heart rate variability and an accelerometer to measure body movements, sleep stages and sleep statistics were automatically computed from overnight recordings. Sleep-wake, 4-class (wake/N1 + N2/N3/REM) and 3-class (wake/NREM/REM) classifiers were trained on 135 simultaneously recorded PSG and PPG recordings of 101 healthy participants and validated on 80 recordings of 51 healthy middle-aged adults. Epoch-by-epoch agreement and sleep statistics were compared with actigraphy for a subset of the validation set. The sleep-wake classifier obtained an epoch-by-epoch Cohen's κ between PPG and PSG sleep stages of 0.55 ± 0.14, sensitivity to wake of 58.2 ± 17.3%, and accuracy of 91.5 ± 5.1%. κ and sensitivity were significantly higher than with actigraphy (0.40 ± 0.15 and 45.5 ± 19.3%, respectively). The 3-class classifier achieved a κ of 0.46 ± 0.15 and accuracy of 72.9 ± 8.3%, and the 4-class classifier, a κ of 0.42 ± 0.12 and accuracy of 59.3 ± 8.5%. The moderate epoch-by-epoch agreement and, in particular, the good agreement in terms of sleep statistics suggest that this technique is promising for long-term sleep monitoring, although more evidence is needed to understand whether it can complement PSG in clinical practice. It also offers an improvement in sleep/wake detection over actigraphy for healthy individuals, although this must be confirmed on a larger, clinical population. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  3. Binary-corrected velocity dispersions from single- and multi-epoch radial velocities: massive stars in R136 as a test case

    NASA Astrophysics Data System (ADS)

    Cottaar, M.; Hénault-Brunet, V.

    2014-02-01

    Orbital motions from binary stars can broaden the observed line-of-sight velocity distribution of a stellar system and artificially inflate the measured line-of-sight velocity dispersion, which can in turn lead to erroneous conclusions about the dynamical state of the system. Recently, a maximum-likelihood procedure was proposed to recover the intrinsic velocity dispersion of a resolved star cluster from a single epoch of radial velocity data of individual stars, which was achieved by simultaneously fitting the intrinsic velocity distribution of the single stars and the centers of mass of the binaries along with the velocity shifts caused by binary orbital motions. Assuming well-characterized binary properties, this procedure can accurately reproduce intrinsic velocity dispersions below 1 km s-1 for solar-type stars. Here we investigate the systematic offsets induced when the binary properties are uncertain and we show that two epochs of radial velocity data with an appropriate baseline can help to mitigate these systematic effects. We first test the method described above using Monte Carlo simulations, taking into account the large uncertainties in the binary properties of OB stars. We then apply it to radial velocity data in the young massive cluster R136 for which the intrinsic velocity dispersion of O-type stars is known from an intensive multi-epoch approach. For typical velocity dispersions of young massive clusters (≳4 km s-1) and with a single epoch of data, we demonstrate that the method can just about distinguish between a cluster in virial equilibrium and an unbound cluster. This is due to the higher spectroscopic binary fraction and more loosely constrained distributions of orbital parameters of OB stars compared to solar-type stars. By extending the maximum-likelihood method to multi-epoch data, we show that the accuracy on the fitted velocity dispersion can be improved by only a few percent by using only two epochs of radial velocities. This procedure offers a promising method of accurately measuring the intrinsic stellar velocity dispersion in other systems for which the binary properties are poorly constrained, for example, young clusters and associations whose luminosity is dominated by OB stars. Appendix A is available in electronic form at http://www.aanda.org

  4. Multi-epoch VLTI-PIONIER imaging of the supergiant V766 Cen

    NASA Astrophysics Data System (ADS)

    Wittkowski, M.; Abellán, F. J.; Arroyo-Torres, B.; Chiavassa, A.; Guirado, J. C.; Marcaide, J. M.; Alberdi, A.; de Wit, W. J.; Hofmann, K.-H.; Meilland, A.; Millour, F.; Mohamed, S.; Sanchez-Bermudez, J.

    2017-09-01

    Context. The star V766 Cen (=HR 5171A) was originally classified as a yellow hypergiant but lately found to more likely be a 27-36 M⊙ red supergiant (RSG). Recent observations indicated a close eclipsing companion in the contact or common-envelope phase. Aims: Here, we aim at imaging observations of V766 Cen to confirm the presence of the close companion. Methods: We used near-infrared H-band aperture synthesis imaging at three epochs in 2014, 2016, and 2017, employing the PIONIER instrument at the Very Large Telescope Interferometer (VLTI). Results: The visibility data indicate a mean Rosseland angular diameter of 4.1 ± 0.8 mas, corresponding to a radius of 1575 ± 400 R⊙. The data show an extended shell (MOLsphere) of about 2.5 times the Rosseland diameter, which contributes about 30% of the H-band flux. The reconstructed images at the 2014 epoch show a complex elongated structure within the photospheric disk with a contrast of about 10%. The second and third epochs show qualitatively and quantitatively different structures with a single very bright and narrow feature and high contrasts of 20-30%. This feature is located toward the south-western limb of the photospheric stellar disk. We estimate an angular size of the feature of 1.7 ± 0.3 mas, corresponding to a radius of 650 ± 150 R⊙, and giving a radius ratio of 0.42+0.35-0.10 compared to the primary stellar disk. Conclusions: We interpret the images at the 2016 and 2017 epochs as showing the close companion, or a common envelope toward the companion, in front of the primary. At the 2014 epoch, the close companion is behind the primary and not visible. Instead, the structure and contrast at the 2014 epoch are typical of a single RSG harboring giant photospheric convection cells. The companion is most likely a cool giant or supergiant star with a mass of 5+15-3 M⊙. Based on observations made with the VLT Interferometer at Paranal Observatory under programme IDs 092.D-0096, 092.C-0312, and 097.D-0286.Olivier Chesneau was PI of the program 092.D-0096. He unfortunately passed away before seeing the results coming out of it. This Letter may serve as a posthumous tribute to his inspiring work on this source.

  5. Severe hypercalcaemia and hypophosphataemia with an optimised preterm parenteral nutrition formulation in two epochs of differing phosphate supplementation.

    PubMed

    Mulla, Shaveta; Stirling, Susan; Cowey, Sarah; Close, Rosie; Pullan, Sara; Howe, Rosalind; Radbone, Lynne; Clarke, Paul

    2017-09-01

    To compare in two epochs of differing phosphate provision serum calcium, phosphate, potassium, and sodium concentrations and the frequency of abnormality of these electrolytes and of sepsis in preterm infants who received an optimised higher amino acid-content formulation. Retrospective cohort study at a single tertiary-level neonatal unit. Preterm infants given parenteral nutrition (PN) in the first postnatal week during two discrete 6-month epochs in 2013-2014. In epoch 1 the Ca 2+ :PO 4 molar ratio of the PN formulation was ~1.3-1.5:1 (1.7 mmol Ca 2+ and 1.1 mmol PO 4 per 100 mL aqueous phase) and in epoch 2 was 1.0:1 via extra phosphate supplementation (1.7 mmol Ca 2+ and 1.7 mmol PO 4 per 100 mL). Peak calcium and nadir phosphate and potassium concentrations, and proportions with severe hypercalcaemia (Ca 2+ >3.0 mmol/L), hypophosphataemia (PO 4 <1.5 mmol/L), and hypokalaemia (K + <3.5 mmol/L) within the first postnatal week. In epoch 2, peak calcium concentrations were lower than in epoch 1 (geometric means: 2.83 mmol/L vs 3.09 mmol/L, p value<0.0001), fewer babies were severely hypercalcaemic (10/49, 20%, vs 31/51, 61%, p value<0.0001); nadir plasma phosphate concentrations were higher (means: 1.54 mmol/L vs 1.32 mmol/L, p value=0.006), and there were fewer cases of hypophosphataemia (17/49, 35% vs 31/51, 61%, p value=0.009) and hypokalaemia (12/49, 25% vs 23/51, 45%, p value=0.03). Reverting from a PN Ca 2+ :PO 4 molar ratio of 1.3-1.5:1 to a ratio of 1.0:1 was associated with a lower incidence and severity of hypophosphataemia and hypercalcaemia. For preterm infants given higher concentrations of amino acids (≥2.5 g/kg/day) from postnatal day 1, an equimolar Ca 2+ :PO 4 ratio may be preferable during the first postnatal week. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  6. Swift follow-up of the flaring blazar PKS 0250-225

    NASA Astrophysics Data System (ADS)

    Dutka, Michael; Ojha, Roopesh; Donato, DavidePottschmidt, Katja

    2012-11-01

    Following the gamma-ray flaring activity of the flat spectrum radio quasar PKS 0250-225 (also known as 2FGL J0252.7-2218, Nolan et al. 2012, ApJS, 199, 31) detected by Fermi LAT on 2012 November 13 (ATel #4574) two Swift target of opportunity observations were performed on November 14 and 16. As no significant differences were found between the two epochs the combined results are reported here.

  7. Amazon rain-forest fires.

    PubMed

    Sanford, R L; Saldarriaga, J; Clark, K E; Uhl, C; Herrera, R

    1985-01-04

    Charcoal is common in the soils of mature rain forests within 75 kilometers of San Carlos de Rio Negro in the north central Amazon Basin. Carbon-14 dates of soil charcoal from this region indicate that numerous fires have occurred since the mid-Holocene epoch. Charcoal is most common in tierra firme forest Oxisols and Ultisols and less common in caatinga and igapo forest soils. Climatic changes or human activities, or both, have caused rain-forest fires.

  8. Linking express saccade occurance to stimulus properties and sensorimotor integration in the superior colliculus.

    PubMed

    Marino, Robert A; Levy, Ron; Munoz, Douglas P

    2015-08-01

    Express saccades represent the fastest possible eye movements to visual targets with reaction times that approach minimum sensory-motor conduction delays. Previous work in monkeys has identified two specific neural signals in the superior colliculus (SC: a midbrain sensorimotor integration structure involved in gaze control) that are required to execute express saccades: 1) previsual activity consisting of a low-frequency increase in action potentials in sensory-motor neurons immediately before the arrival of a visual response; and 2) a transient visual-sensory response consisting of a high-frequency burst of action potentials in visually responsive neurons resulting from the appearance of a visual target stimulus. To better understand how these two neural signals interact to produce express saccades, we manipulated the arrival time and magnitude of visual responses in the SC by altering target luminance and we examined the corresponding influences on SC activity and express saccade generation. We recorded from saccade neurons with visual-, motor-, and previsual-related activity in the SC of monkeys performing the gap saccade task while target luminance was systematically varied between 0.001 and 42.5 cd/m(2) against a black background (∼0.0001 cd/m(2)). Our results demonstrated that 1) express saccade latencies were linked directly to the arrival time in the SC of visual responses produced by abruptly appearing visual stimuli; 2) express saccades were generated toward both dim and bright targets whenever sufficient previsual activity was present; and 3) target luminance altered the likelihood of producing an express saccade. When an express saccade was generated, visuomotor neurons increased their activity immediately before the arrival of the visual response in the SC and saccade initiation. Furthermore, the visual and motor responses of visuomotor neurons merged into a single burst of action potentials, while the visual response of visual-only neurons was unaffected. A linear combination model was used to test which SC signals best predicted the likelihood of producing an express saccade. In addition to visual response magnitude and previsual activity of saccade neurons, the model identified presaccadic activity (activity occurring during the 30-ms epoch immediately before saccade initiation) as a third important signal for predicting express saccades. We conclude that express saccades can be predicted by visual, previsual, and presaccadic signals recorded from visuomotor neurons in the intermediate layers of the SC. Copyright © 2015 the American Physiological Society.

  9. Linking express saccade occurance to stimulus properties and sensorimotor integration in the superior colliculus

    PubMed Central

    Levy, Ron; Munoz, Douglas P.

    2015-01-01

    Express saccades represent the fastest possible eye movements to visual targets with reaction times that approach minimum sensory-motor conduction delays. Previous work in monkeys has identified two specific neural signals in the superior colliculus (SC: a midbrain sensorimotor integration structure involved in gaze control) that are required to execute express saccades: 1) previsual activity consisting of a low-frequency increase in action potentials in sensory-motor neurons immediately before the arrival of a visual response; and 2) a transient visual-sensory response consisting of a high-frequency burst of action potentials in visually responsive neurons resulting from the appearance of a visual target stimulus. To better understand how these two neural signals interact to produce express saccades, we manipulated the arrival time and magnitude of visual responses in the SC by altering target luminance and we examined the corresponding influences on SC activity and express saccade generation. We recorded from saccade neurons with visual-, motor-, and previsual-related activity in the SC of monkeys performing the gap saccade task while target luminance was systematically varied between 0.001 and 42.5 cd/m2 against a black background (∼0.0001 cd/m2). Our results demonstrated that 1) express saccade latencies were linked directly to the arrival time in the SC of visual responses produced by abruptly appearing visual stimuli; 2) express saccades were generated toward both dim and bright targets whenever sufficient previsual activity was present; and 3) target luminance altered the likelihood of producing an express saccade. When an express saccade was generated, visuomotor neurons increased their activity immediately before the arrival of the visual response in the SC and saccade initiation. Furthermore, the visual and motor responses of visuomotor neurons merged into a single burst of action potentials, while the visual response of visual-only neurons was unaffected. A linear combination model was used to test which SC signals best predicted the likelihood of producing an express saccade. In addition to visual response magnitude and previsual activity of saccade neurons, the model identified presaccadic activity (activity occurring during the 30-ms epoch immediately before saccade initiation) as a third important signal for predicting express saccades. We conclude that express saccades can be predicted by visual, previsual, and presaccadic signals recorded from visuomotor neurons in the intermediate layers of the SC. PMID:26063770

  10. Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship.

    PubMed

    Arem, Hannah; Moore, Steven C; Patel, Alpa; Hartge, Patricia; Berrington de Gonzalez, Amy; Visvanathan, Kala; Campbell, Peter T; Freedman, Michal; Weiderpass, Elisabete; Adami, Hans Olov; Linet, Martha S; Lee, I-Min; Matthews, Charles E

    2015-06-01

    The 2008 Physical Activity Guidelines for Americans recommended a minimum of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic-equivalent hours per week) of aerobic activity for substantial health benefit and suggested additional benefits by doing more than double this amount. However, the upper limit of longevity benefit or possible harm with more physical activity is unclear. To quantify the dose-response association between leisure time physical activity and mortality and define the upper limit of benefit or harm associated with increased levels of physical activity. We pooled data from 6 studies in the National Cancer Institute Cohort Consortium (baseline 1992-2003). Population-based prospective cohorts in the United States and Europe with self-reported physical activity were analyzed in 2014. A total of 661,137 men and women (median age, 62 years; range, 21-98 years) and 116,686 deaths were included. We used Cox proportional hazards regression with cohort stratification to generate multivariable-adjusted hazard ratios (HRs) and 95% CIs. Median follow-up time was 14.2 years. Leisure time moderate- to vigorous-intensity physical activity. The upper limit of mortality benefit from high levels of leisure time physical activity. Compared with individuals reporting no leisure time physical activity, we observed a 20% lower mortality risk among those performing less than the recommended minimum of 7.5 metabolic-equivalent hours per week (HR, 0.80 [95% CI, 0.78-0.82]), a 31% lower risk at 1 to 2 times the recommended minimum (HR, 0.69 [95% CI, 0.67-0.70]), and a 37% lower risk at 2 to 3 times the minimum (HR, 0.63 [95% CI, 0.62-0.65]). An upper threshold for mortality benefit occurred at 3 to 5 times the physical activity recommendation (HR, 0.61 [95% CI, 0.59-0.62]); however, compared with the recommended minimum, the additional benefit was modest (31% vs 39%). There was no evidence of harm at 10 or more times the recommended minimum (HR, 0.69 [95% CI, 0.59-0.78]). A similar dose-response relationship was observed for mortality due to cardiovascular disease and to cancer. Meeting the 2008 Physical Activity Guidelines for Americans minimum by either moderate- or vigorous-intensity activities was associated with nearly the maximum longevity benefit. We observed a benefit threshold at approximately 3 to 5 times the recommended leisure time physical activity minimum and no excess risk at 10 or more times the minimum. In regard to mortality, health care professionals should encourage inactive adults to perform leisure time physical activity and do not need to discourage adults who already participate in high-activity levels.

  11. Visualizing the Anthropocene: Human Land Use History and Environmental Management

    Treesearch

    Richard D. Periman

    2006-01-01

    The term “Anthropocene” defines the current, human-dominated, geological epoch of human-caused environmental influences. Some researchers believe that the beginning of this epoch coincides with the inception of the Industrial Revolution (Crutzen and Stoermer 2000). Research is revealing that humans have affected environments on global and local scales for millennia....

  12. A Cepheid Distance to NGC 4603 in the Centaurus Cluster

    NASA Technical Reports Server (NTRS)

    Madore, B.; Newman, J.; Zepf, S.; Davis, M.; Freedman, W.; Madore, B.; Stetson, P.; Silbermann, N.; Phelps, R.

    1999-01-01

    In an attempt to use Cepheid variables to determine the distance to the Centaurus cluster, we have obtained images of NGC 4603 with the Hubble Space Telescope for 9 epochs (totalling 24 orbits) over 14 months in the F555W filter and 2 epochs (totalling 6 orbits) in the F814W filter.

  13. Toward a Communication Theory Focused on Humankind's Future.

    ERIC Educational Resources Information Center

    Ternent, William A.; Ternent, Janet A.

    This speech presents a model of human communication which integrates the existential philosophy of Martin Buber with the communication views of Jonas Salk. In his book, "The Survival of the Wisest," Salk characterizes an "Epoch A" to describe the values and behaviors of the past and an "Epoch B" to describe the necessary values and behaviors for…

  14. Mean Energy Density of Photogenerated Magnetic Fields Throughout the EoR

    NASA Astrophysics Data System (ADS)

    Durrive, Jean-Baptiste; Tashiro, Hiroyuki; Langer, Mathieu; Sugiyama, Naoshi

    2018-05-01

    There seems to be magnetic fields at all scales and epochs in our Universe, but their origin at large scales remains an important open question of cosmology. In this work we focus on the generation of magnetic fields in the intergalactic medium due to the photoionizations by the first galaxies, all along the Epoch of Reionization. Based on previous studies which considered only isolated sources, we develop an analytical model to estimate the mean magnetic energy density accumulated in the Universe by this process. In our model, without considering any amplification process, the Universe is globally magnetized by this mechanism to the order of, at least, several 10-18 G during the Epoch of Reionization (i.e. a few 10-20 G comoving).

  15. Observable Signatures of Cosmic Reionization and the End of the Dark Ages

    NASA Astrophysics Data System (ADS)

    Shapiro, Paul R.; Iliev, I. T.; Mellema, G.; Pen, U. L.; McDonald, P.; Bond, J. R.; Alvarez, M.; Ahn, K.

    2007-12-01

    Reionization exerted a strong feedback effect which left its imprint on all scales and on radiation backgrounds at all wavelengths. When the first stars formed inside minihalos of mass 106 solar masses at z > 20, ionizing radiation heated and expelled the gas inside their minihalos and escaped to create intergalactic H II regions. As these H II regions grew, their ionization fronts encountered other minihalos, which blocked their path and trapped them, causing this minihalo gas, too, to escape in a photoevaporative wind. Further star formation inside minihalos was affected not only by these I-fronts, but also by the rising dissociating background. Eventually, hierarchical clustering formed dwarf galaxies > 108 solar masses, where atomic cooling was effective enough to trigger more star formation, and intergalactic H II regions grew and merged to become 10's of comoving Mpc's in size. Inside these H II regions, gas pressure inhibited gravitational collapse, so the minimum mass of newly-formed galaxies jumped above 109 solar masses. Reionization ended when the intergalactic H II regions finally overlapped everywhere. We have studied this process by a variety of techniques, on a hierarchy of mass- and length-scales. The latter span the range from interiors of minihalos, to giant H II regions produced by the clustered formation of galaxies, to large-scale structure of the patchy distribution of neutral and ionized gas during the epoch of reionization. These results lead to predictions of a fluctuating background of redshifted 21-cm line radiation, temperature and polarization anisotropy of the CMB, gaps in the Gunn-Peterson absorption spectra of high-z quasars, and distortion of the luminosity function and spatial clustering of Lyman alpha emission-line galaxies during this epoch, among other things. I will summarize the latest theoretical developments in this talk. This work supported by NASA grants NNX07AH09G and NNG04GI77G and NSF AST-0708176.

  16. Effects of mental tasks on the cardiorespiratory synchronization.

    PubMed

    Zhang, Jianbao; Yu, Xiaolin; Xie, Dongdong

    2010-01-31

    The cardiovascular and respiratory systems are functionally related to each other, but it is unclear if the cerebral cortex can affect their interaction. The effect of a mental task on the synchronization between cardiovascular and respiratory systems was investigated in the article. Electroencephalogram (EEG), electrocardiogram (ECG) and respiratory signal (RES) were collected from 29 healthy male subjects during the mental arithmetic (MA) task and the synchrogram was used to estimate the strength of cardiorespiratory synchronization. Our results showed that MA task significantly increased the breath rate, the heart rate and the EEG power spectral energy in theta band at FC3, FC4 and C4 electrodes (p<0.01), decreased the duration of cardiorespiratory synchronization epochs (p<0.05). Moreover the duration of cardiorespiratory synchronization epochs during MA task was negatively correlated with the EEG power spectral energy in theta band at FC3, FC4 and C4 electrodes and the sympathetic activity (p<0.05). The results demonstrated that ANS and cerebral cortex are implicated in the changes of cardiorespiratory synchronization during MA task. Copyright 2009 Elsevier B.V. All rights reserved.

  17. Technologies for Low Frequency Radio Observations of the Cosmic Dawn

    NASA Technical Reports Server (NTRS)

    Jones, Dayton L.

    2014-01-01

    The Jet Propulsion Laboratory (JPL) is developing concepts and technologies for low frequency radio astronomy space missions aimed at observing highly redshifted neutral Hydrogen from the Dark Ages. This is the period of cosmic history between the recombination epoch when the microwave background radiation was produced and the re-ionization of the intergalactic medium by the first generation of stars (Cosmic Dawn). This period, at redshifts greater than about 20, is a critical epoch for the formation and evolution of large-scale structure in the universe. The 21-cm spectral line of Hydrogen provides the most promising method for directly studying the Dark Ages, but the corresponding frequencies at such large redshifts are only tens of MHz and thus require space-based observations to avoid terrestrial RFI and ionospheric absorption and refraction. This paper reports on the status of several low frequency technology development activities at JPL, including deployable bi-conical dipoles for a planned lunar-orbiting mission, and both rover-deployed and inflation-deployed long dipole antennas for use on the lunar surface.

  18. Like/dislike analysis using EEG: determination of most discriminative channels and frequencies.

    PubMed

    Yılmaz, Bülent; Korkmaz, Sümeyye; Arslan, Dilek Betül; Güngör, Evrim; Asyalı, Musa H

    2014-02-01

    In this study, we have analyzed electroencephalography (EEG) signals to investigate the following issues, (i) which frequencies and EEG channels could be relatively better indicators of preference (like or dislike decisions) of consumer products, (ii) timing characteristic of "like" decisions during such mental processes. For this purpose, we have obtained multichannel EEG recordings from 15 subjects, during total of 16 epochs of 10 s long, while they were presented with some shoe photographs. When they liked a specific shoe, they pressed on a button and marked the time of this activity and the particular epoch was labeled as a LIKE case. No button press meant that the subject did not like the particular shoe that was displayed and corresponding epoch designated as a DISLIKE case. After preprocessing, power spectral density (PSD) of EEG data was estimated at different frequencies (4, 5, …, 40 Hz) using the Burg method, for each epoch corresponding to one shoe presentation. Each subject's data consisted of normalized PSD values (NPVs) from all LIKE and DISLIKE cases/epochs coming from all 19 EEG channels. In order to determine the most discriminative frequencies and channels, we have utilized logistic regression, where LIKE/DISLIKE status was used as a categorical (binary) response variable and corresponding NPVs were the continuously valued input variables or predictors. We observed that when all the NPVs (total of 37) are used as predictors, the regression problem was becoming ill-posed due to large number of predictors (compared to the number of samples) and high correlation among predictors. To circumvent this issue, we have divided the frequency band into low frequency (LF) 4-19 Hz and high frequency (HF) 20-40 Hz bands and analyzed the influence of the NPV in these bands separately. Then, using the p-values that indicate how significantly estimated predictor weights are different than zero, we have determined the NPVs and channels that are more influential in determining the outcome, i.e., like/dislike decision. In the LF band, 4 and 5 Hz were found to be the most discriminative frequencies (MDFs). In the HF band, none of the frequencies seemed offer significant information. When both male and female data was used, in the LF band, a frontal channel on the left (F7-A1) and a temporal channel on the right (T6-A2) were found to be the most discriminative channels (MDCs). In the HF band, MDCs were central (Cz-A1) and occipital on the left (O1-A1) channels. The results of like timings suggest that male and female behavior for this set of stimulant images were similar. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  19. Activity-Dependence of Synaptic Vesicle Dynamics

    PubMed Central

    Forte, Luca A.

    2017-01-01

    The proper function of synapses relies on efficient recycling of synaptic vesicles. The small size of synaptic boutons has hampered efforts to define the dynamical states of vesicles during recycling. Moreover, whether vesicle motion during recycling is regulated by neural activity remains largely unknown. We combined nanoscale-resolution tracking of individual synaptic vesicles in cultured hippocampal neurons from rats of both sexes with advanced motion analyses to demonstrate that the majority of recently endocytosed vesicles undergo sequences of transient dynamical states including epochs of directed, diffusional, and stalled motion. We observed that vesicle motion is modulated in an activity-dependent manner, with dynamical changes apparent in ∼20% of observed boutons. Within this subpopulation of boutons, 35% of observed vesicles exhibited acceleration and 65% exhibited deceleration, accompanied by corresponding changes in directed motion. Individual vesicles observed in the remaining ∼80% of boutons did not exhibit apparent dynamical changes in response to stimulation. More quantitative transient motion analyses revealed that the overall reduction of vesicle mobility, and specifically of the directed motion component, is the predominant activity-evoked change across the entire bouton population. Activity-dependent modulation of vesicle mobility may represent an important mechanism controlling vesicle availability and neurotransmitter release. SIGNIFICANCE STATEMENT Mechanisms governing synaptic vesicle dynamics during recycling remain poorly understood. Using nanoscale resolution tracking of individual synaptic vesicles in hippocampal synapses and advanced motion analysis tools we demonstrate that synaptic vesicles undergo complex sets of dynamical states that include epochs of directed, diffusive, and stalled motion. Most importantly, our analyses revealed that vesicle motion is modulated in an activity-dependent manner apparent as the reduction in overall vesicle mobility in response to stimulation. These results define the vesicle dynamical states during recycling and reveal their activity-dependent modulation. Our study thus provides fundamental new insights into the principles governing synaptic function. PMID:28954868

  20. Hierarchical porous silver metal using Pluronic F-127 and graphene oxide as reinforcing agents for the reduction of o-nitroaniline to 1, 2-benzenediamine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bano, Mustri; Ahirwar, Devendra; Thomas, Molly

    An elegant method is used to prepare silver monoliths with Pluronic F-127(F-127) as sacrificial template by modified sol-gel method. Si nanoparticles (SiNPs) and graphene oxide (GO) are added in situ to Ag/F-127 hydrogel for the reduction of ο-nitroaniline (ο-NA) to 1, 2-benzenediamine. Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Thermogravimetric analysis (TGA), Raman Spectroscopy, Powder X-Ray Diffraction (PXRD) analysis and Brunauer-Emmett-Teller (BET) Nitrogen adsorption techniques were used for characterization of monoliths. An epoch-making catalytic activity of Ag/F-127/GO monoliths is observed in the reduction of ο-NA to 1, 2-benzenediamine in presence of NaBH{sub 4} inmore » aqueous media. The catalyst Ag/F-127/GO took only 2 min which is the minimum time reported so far with significant rate constant claimed itself a leading catalyst for the reduction of ο-NA to 1,2-benzenediamine. Pseudo first order rate constant (k) and Turn over frequency (TOF) values are 0.231 min{sup −1} and 30.053×10{sup 19} molecules min{sup −1} respectively suggest that the catalyst has industrial importance. Recyclability and stability of Ag/F-127/GO catalyst are studied successfully up to 10 cycles. Energy of activation (E{sub a}), and thermodynamic parameters viz. activation enthalpy (ΔH{sup ≠}), activation Gibbs free energy (ΔG{sup ≠}), and entropy of activation (ΔS{sup ≠}) were also ascertained. Catalytic activities of Ag/F-127, Ag/F-127/Dextran, Ag/F-127/Trimethylbenzene (TMB), Ag/F-127/SiNPs, and Ag/F-127/Si/GO monoliths were also studied. - Graphical abstract: Significant catalytic activities of silver monoliths against the reduction of ο-NA to 1,2 benzenediamine. - Highlights: • A new catalyst synthesized Ag/F-127/GO for the reduction of ο- NA to 1, 2- benzenediamine took only 2 min. • Turn over frequency of as synthesized catalyst was 30.053×10{sup 19} molecules min{sup −1} claimed itself a leading catalyst. • Recyclability of the catalyst was up to 10 cycles. • The synthesis is non toxic, economically viable and environmentally benign.« less

  1. Historic mass movements recorded in the sediments of Hallstätter See (Upper Austria) - natural hazards at a UNESCO World Cultural Heritage Site

    NASA Astrophysics Data System (ADS)

    Lauterbach, Stefan; Strasser, Michael; Tjallingii, Rik; Spötl, Christoph; Brauer, Achim

    2017-04-01

    Human activity associated with salt mining in Hallstatt (Upper Austria) can be traced back to the Neolithic and underground salt mining in the area is documented since the Middle Bronze Age. The cultural importance of this salt mining and the wealth of archaeological artefacts - particularly from the epoch of the Early Iron Age, for which Hallstatt became the eponym - has been recognized already 20 years ago by assigning the status of a UNESCO World Cultural Heritage Site to the Hallstatt area. Mining activity is well documented for prehistoric times and known to have been repeatedly affected by large mass movements, destroying mining facilities, for example, at the end of the Bronze Age and during the Late Iron Age. In contrast, evidence of mining activity in the Common Era until the late 13th century AD is scarce, which could be related to socio-economic changes as well as mass movement activity, possibly biasing the archaeological record. Within a project aiming at reconstructing past flood activity of the Traun River, a major tributary of the Danube, a ca. 16-m-long sediment core has been recovered from Hallstätter See. The sediments are continuously cm- to sub-mm-scale laminated, reflecting seasonally variable detrital input by the Traun River and the smaller tributaries. However, an outstanding feature of the sediment record are two meter-scale event layers. The upper one is characterized by a basal mass-transport deposit of 2.50 m thickness, containing folded laminated sediments, homogeneous sediments with liquefaction structures and large stones of up to 4 cm in diameter, which is overlain by a co-genetic turbidite of 1.50 m thickness. From the lower event layer only the topmost part of the turbiditic sequence was recovered, revealing a (minimum) thickness of 1.50 m. Based on their sedimentological characteristics, both event layers are interpreted as the subaqueous continuation of large-scale mass movements, which occurred during the last 2000 years and likely originated from the Plassen Massif where the Hallstatt salt mining area is located. This indicates that past mass movement activity not only threatened prehistoric salt mining, but repeatedly occurred during the Common Era, which could possibly explain the lack of archaeological evidence for mining activity between the Late Iron Age and the late 13th century AD.

  2. The Square Kilometre Array Epoch of Reionisation and Cosmic Dawn Experiment

    NASA Astrophysics Data System (ADS)

    Trott, Cathryn M.

    2018-05-01

    The Square Kilometre Array (SKA) Epoch of Reionisation and Cosmic Dawn (EoR/CD) experiments aim to explore the growth of structure and production of ionising radiation in the first billion years of the Universe. Here I describe the experiments planned for the future low-frequency components of the Observatory, and work underway to define, design and execute these programs.

  3. Geomagnetic reversal in brunhes normal polarity epoch.

    PubMed

    Smith, J D; Foster, J H

    1969-02-07

    The magnetic stratigraphly of seven cores of deep-sea sediment established the existence of a short interval of reversed polarity in the upper part of the Brunches epoch of normal polarity. The reversed zone in the cores correlates well with paleontological boundaries and is named the Blake event. Its boundaries are estimated to be 108,000 and 114,000 years ago +/- 10 percent.

  4. Accounting for phase drifts in SSVEP-based BCIs by means of biphasic stimulation.

    PubMed

    Wu, Hung-Yi; Lee, Po-Lei; Chang, Hsiang-Chih; Hsieh, Jen-Chuen

    2011-05-01

    This study proposes a novel biphasic stimulation technique to solve the issue of phase drifts in steady-state visual evoked potential (SSVEPs) in phase-tagged systems. Phase calibration was embedded in stimulus sequences using a biphasic flicker, which is driven by a sequence with alternating reference and phase-shift states. Nine subjects were recruited to participate in off-line and online tests. Signals were bandpass filtered and segmented by trigger signals into reference and phase-shift epochs. Frequency components of SSVEP in the reference and phase-shift epochs were extracted using the Fourier method with a 50% overlapped sliding window. The real and imaginary parts of the SSVEP frequency components were organized into complex vectors in each epoch. Hotelling's t-square test was used to determine the significances of nonzero mean vectors. The rejection of noisy data segments and the validation of gaze detections were made based on p values. The phase difference between the valid mean vectors of reference and phase-shift epochs was used to identify user's gazed targets in this system. Data showed an average information transfer rate of 44.55 and 38.21 bits/min in off-line and online tests, respectively. © 2011 IEEE

  5. Superposed epoch analysis of ion temperatures during CME- and CIR/HSS-driven storms

    NASA Astrophysics Data System (ADS)

    Keesee, A. M.; Scime, E. E.

    2012-12-01

    The NASA Two Wide-angle Imaging Neutral atom Spectrometers (TWINS) Mission provides a global view of the magnetosphere with near-continuous coverage. Utilizing a novel technique to calculate ion temperatures from the TWINS energetic neutral atom (ENA) measurements, we generate ion temperature maps of the magnetosphere. These maps can be used to study ion temperature evolution during geomagnetic storms. A superposed epoch analysis of the ion temperature evolution during 48 storms will be presented. Zaniewski et al. [2006] performed a superposed epoch analysis of ion temperatures by storm interval using data from the MENA instrument on the IMAGE mission, demonstrating significant dayside ion heating during the main phase. The TWINS measurements provide more continuous coverage and improved spatial and temporal resolution. Denton and Borovsky [2008] noted differences in ion temperature evolution at geosynchronous orbit between coronal mass ejection (CME)- and corotating interaction region (CIR)/high speed stream (HSS)- driven storms. Using our global ion temperature maps, we have found consistent results for select individual storms [Keesee et al., 2012]. We will present superposed epoch analyses for the subgroups of CME- and CIR/HSS-driven storms to compare global ion temperature evolution during the two types of storms.

  6. Simultaneous infrared and optical observations of the transiting debris cloud around WD 1145+017

    NASA Astrophysics Data System (ADS)

    Zhou, G.; Kedziora-Chudczer, L.; Bailey, J.; Marshall, J. P.; Bayliss, D. D. R.; Stockdale, C.; Nelson, P.; Tan, T. G.; Rodriguez, J. E.; Tinney, C. G.; Dragomir, D.; Colon, K.; Shporer, A.; Bento, J.; Sefako, R.; Horne, K.; Cochran, W.

    2016-12-01

    We present multiwavelength photometric monitoring of WD 1145+017, a white dwarf exhibiting periodic dimming events interpreted to be the transits of orbiting, disintegrating planetesimals. Our observations include the first set of near-infrared light curves for the object, obtained on multiple nights over the span of 1 month, and recorded multiple transit events with depths varying between ˜20 and 50 per cent. Simultaneous near-infrared and optical observations of the deepest and longest duration transit event were obtained on two epochs with the Anglo-Australian Telescope and three optical facilities, over the wavelength range of 0.5-1.2 μm. These observations revealed no measurable difference in transit depths for multiple photometric pass bands, allowing us to place a 2σ lower limit of 0.8 μm on the grain size in the putative transiting debris cloud. This conclusion is consistent with the spectral energy distribution of the system, which can be fit with an optically thin debris disc with minimum particle sizes of 10^{+5}_{-3} μm.

  7. Future Earth: Advancing Civic Understanding of the Anthropocene

    NASA Astrophysics Data System (ADS)

    Schultz, Colin

    2014-08-01

    The Anthropocene, a term first coined in the 1980s by biologist Eugene Stoermer, is a word that encapsulates a powerful idea—that the world is now in the throes of a novel geological epoch, a period of time in which human activity, not natural cycles, dominates many of Earth's chemical, geological, and biological systems. The growing realization of our importance has caused a reanalysis, both scientifically and ethically, of our relationship with the natural world.

  8. Searching for Missing Pieces for Solar Flare Forecasting

    NASA Astrophysics Data System (ADS)

    Leka, K. D.

    2015-12-01

    Knowledge of the state of the solar photospheric magnetic field at a single instant in time does not appear sufficient to uniquely predict the size and timing of impending solar flares. Such knowledge may provide necessary conditions, such as estimates of the magnetic energy needed for a flare to occur. Given the necessary conditions, it is often assumed that the evolution of the field, possibly by only a small amount, may trigger the onset of a flare. We present the results of a study using time series of photospheric vector field data from the Helioseismic and Magnetic Imager (HMI) on NASA's Solar Dynamics Observatory (SDO) to quantitatively parameterize both the state and evolution of solar active regions - their complexity, magnetic topology and energy - as related to solar flare events. We examine both extensive and intensive parameters and their short-term temporal behavior, in the context of predicting flares at various thresholds. Statistical tests based on nonparametric Discriminant Analysis are used to compare pre-flare epochs to a control group of flare-quiet epochs and active regions. Results regarding the type of photospheric signature examined and the efficacy of using the present state vs. temporal evolution to predict solar flares is quantified by standard skill scores. This work is made possible by contracts NASA NNH12CG10C and NOAA/SBIR WC-133R-13-CN-0079.

  9. The Conundrum of the Solar Pre-Flare Photospheric State.

    NASA Astrophysics Data System (ADS)

    Leka, KD; Barnes, Graham; Wagner, Eric

    2015-08-01

    Knowledge of the state of the solar photospheric magnetic field at a single instant in time does not appear sufficient to predict the size and timing of impending solar flares. Such knowledge may provide necessary conditions, such as the free magnetic energy needed for a flare to occur. Given the necessary conditions, it is often assumed that the evolution of the field, possibly by only a small amount, may trigger the onset of a flare. We present the results of a study using time series of photospheric vector field data from the Helioseismic and Magnetic Imager (HMI) on NASA's Solar Dynamics Observatory (SDO) to quantitatively parameterize both the state and evolution of solar active regions - their complexity, magnetic topology and energy - as related to solar flare events. We examine both extensive and intensive parameters and their temporal behavior, in the context of both large and small flaring episodes. Statistical tests based on nonparametric Discriminant Analysis are used to compare pre-flare epochs to a control group of flare-quiet epochs and active regions. Results regarding the type of photospheric signature examined and the efficacy of using the present state vs. temporal evolution to predict solar flares is quantified by standard skill scores.This work is made possible by contracts NASA NNH12CG10C and NOAA/SBIR WC-133R-13-CN-0079.

  10. Electrophysiological Correlates of Reading the Single- and Interactive-Mind

    PubMed Central

    Wang, Yi-Wen; Zheng, Yu-Wei; Lin, Chong-De; Wu, Jie; Shen, De-Li

    2011-01-01

    Understanding minds is the cognitive basis of successful social interaction. In everyday life, human mental activity often happens at the moment of social interaction among two or multiple persons instead of only one-person. Understanding the interactive mind of two- or multi-person is more complex and higher than understanding the single-person mind in the hierarchical structure of theory of mind. Understanding the interactive mind maybe differentiate from understanding the single mind. In order to examine the dissociative electrophysiological correlates of reading the single mind and reading the interactive mind, the 64 channels event-related potentials were recorded while 16 normal adults were observing three kinds of Chinese idioms depicted physical scenes, one-person with mental activity, and two- or multi-person with mental interaction. After the equivalent N400, in the 500- to 700-ms epoch, the mean amplitudes of late positive component (LPC) over frontal for reading the single mind and reading the interactive mind were significantly more positive than for physical representation, while there was no difference between the former two. In the 700- to 800-ms epoch, the mean amplitudes of LPC over frontal–central for reading the interactive mind were more positive than for reading the single mind and physical representation, while there was no difference between the latter two. The present study provides electrophysiological signature of the dissociations between reading the single mind and reading the interactive mind. PMID:21845178

  11. AGN Variability in the GOODS Fields

    NASA Astrophysics Data System (ADS)

    Sarajedini, Vicki

    2007-07-01

    Variability is a proven method to identify intrinsically faint active nuclei in galaxies found in deep HST surveys. We propose to extend our short-term variability study of the GOODS fields to include the more recent epochs obtained via supernovae searchers, increasing the overall time baseline from 6 months to 2.5 years. Based on typical AGN lightcurves, we expect to detect 70% more AGN by including these more recent epochs. Variable-detected AGN samples complement current X-ray and mid-IR surveys for AGN by providing unambigous evidence of nuclear activity. Additionallty, a significant number of variable nuclei are not associated with X-ray or mid-IR sources and would thus go undetected. With the increased time baseline, we will be able to construct the structure function {variability amplitude vs. time} for low-luminosity AGN to z 1. The inclusion of the longer time interval will allow for better descrimination among the various models describing the nature of AGN variability. The variability survey will be compared against spectroscopically selected AGN from the Team Keck Redshift Survey of the GOODS-N and the upcoming Flamingos-II NIR survey of the GOODS-S. The high-resolution ACS images will be used to separate the AGN from the host galaxy light and study the morphology, size and environment of the host galaxy. These studies will address questions concerning the nature of low-luminosity AGN evolution and variability at z 1.

  12. Primordial random motions and angular momenta of galaxies and galaxy clusters.

    NASA Technical Reports Server (NTRS)

    Silk, J.; Lea, S.

    1973-01-01

    We study the decay of primordial random motions of galaxies and galaxy clusters in an expanding universe by solving a kinetic equation for the relaxation of differential energy spectra N(E, t). Systematic dissipative energy losses are included, involving gravitational drag by, and accretion of, intergalactic matter, as well as the effect of collisions with other systems. Formal and numerical solutions are described for two distinct modes of galaxy formation in a turbulent medium, corresponding to formation at a distinct epoch and to continuous formation of galaxies. We show that any primordial random motions of galaxies at the present epoch can amount to at most a few km/sec, and that collisions at early epochs can lead to the acquisition of significant amounts of primordial angular momentum.

  13. VizieR Online Data Catalog: Cordoba Carte du Ciel-Astrographic Catalog, CCAC (Orellana+, 2010)

    NASA Astrophysics Data System (ADS)

    Orellana, R. B.; de Biasi, M. S.; Bustos Fierro, I. H.; Calderon, J. H.

    2010-07-01

    This is Cordoba Carte du Ciel-Astrographic Catalog (CCAC) constructed from four Carte du Ciel and one Astrographic Catalog photographic plates for first epoch positions in the region of the open cluster Collinder 132. The plates were digitized using the MAMA measuring machine from the Paris Observatory. Stars from Tycho-2 catalogue (Hog et al., 2000, Cat. I/259) were used as reference stars. Every plate was reduced independently from the others adopting a first order polynomial in the measured coordinates. Proper motions were calculated using the CCAC positions as first epoch, and as second epoch the positions given by UCAC2 (Zacharias et al., 2004, Cat. I/289) and USNO-B1.0 (Monet et al., 2003, Cat. I/284). (2 data files).

  14. International Geomagnetic Reference Field: the 12th generation

    NASA Astrophysics Data System (ADS)

    Thébault, Erwan; Finlay, Christopher C.; Beggan, Ciarán D.; Alken, Patrick; Aubert, Julien; Barrois, Olivier; Bertrand, Francois; Bondar, Tatiana; Boness, Axel; Brocco, Laura; Canet, Elisabeth; Chambodut, Aude; Chulliat, Arnaud; Coïsson, Pierdavide; Civet, François; Du, Aimin; Fournier, Alexandre; Fratter, Isabelle; Gillet, Nicolas; Hamilton, Brian; Hamoudi, Mohamed; Hulot, Gauthier; Jager, Thomas; Korte, Monika; Kuang, Weijia; Lalanne, Xavier; Langlais, Benoit; Léger, Jean-Michel; Lesur, Vincent; Lowes, Frank J.; Macmillan, Susan; Mandea, Mioara; Manoj, Chandrasekharan; Maus, Stefan; Olsen, Nils; Petrov, Valeriy; Ridley, Victoria; Rother, Martin; Sabaka, Terence J.; Saturnino, Diana; Schachtschneider, Reyko; Sirol, Olivier; Tangborn, Andrew; Thomson, Alan; Tøffner-Clausen, Lars; Vigneron, Pierre; Wardinski, Ingo; Zvereva, Tatiana

    2015-05-01

    The 12th generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2014 by the Working Group V-MOD appointed by the International Association of Geomagnetism and Aeronomy (IAGA). It updates the previous IGRF generation with a definitive main field model for epoch 2010.0, a main field model for epoch 2015.0, and a linear annual predictive secular variation model for 2015.0-2020.0. Here, we present the equations defining the IGRF model, provide the spherical harmonic coefficients, and provide maps of the magnetic declination, inclination, and total intensity for epoch 2015.0 and their predicted rates of change for 2015.0-2020.0. We also update the magnetic pole positions and discuss briefly the latest changes and possible future trends of the Earth's magnetic field.

  15. Toward an objective indexing system for ADHD-screening using children's activity monitoring.

    PubMed

    Kam, Hye Jin; Choi, Jong Pil; Park, Rae Woong

    2008-11-06

    Signs of ADHD are discernible in specific situations, and usually assessed according to subjective impressions. We performed a preliminary comparative study from children's activity at a natural classroom environment with 3-axis accelerator for a feasible objective index. From a total of 157 children (7-9 yrs) and clinically diagnosed 24 children out of them, variances in 1-min epoch mean activity had shown significant differences among the subgroups: (1) ADHD=.0194, Other Diseases=.0080, Normal=.0009; (2) ADHD=.0194, non-ADHD=.0057(p<.01, respectively). There were also significant differences in high-level activity (>1.6G) features among subgroups with the same order (p<.01, respectively). ADHD patients exhibited more dispersed activities and higher high-level activity ratio than normal. Activity features can be useful to build an objective indexing system for screening ADHD patients.

  16. Feedback-Driven Trial-by-Trial Learning in Autism Spectrum Disorders

    PubMed Central

    Solomon, Marjorie; Frank, Michael J.; Ragland, J. Daniel; Smith, Anne C.; Niendam, Tara A.; Lesh, Tyler A.; Grayson, David S.; Beck, Jonathan S.; Matter, John C.; Carter, Cameron S.

    2017-01-01

    Objective Impairments in learning are central to autism spectrum disorders. The authors investigated the cognitive and neural basis of these deficits in young adults with autism spectrum disorders using a well-characterized probabilistic reinforcement learning paradigm. Method The probabilistic selection task was implemented among matched participants with autism spectrum disorders (N=22) and with typical development (N=25), aged 18–40 years, using rapid event-related functional MRI. Participants were trained to choose the correct stimulus in high-probability (AB), medium-probability (CD), and low-probability (EF) pairs, presented with valid feedback 80%, 70%, and 60% of the time, respectively. Whole-brain voxel-wise and parametric modulator analyses examined early and late learning during the stimulus and feedback epochs of the task. Results The groups exhibited comparable performance on medium- and low-probability pairs. Typically developing persons showed higher accuracy on the high-probability pair, better win-stay performance (selection of the previously rewarded stimulus on the next trial of that type), and more robust recruitment of the anterior and medial prefrontal cortex during the stimulus epoch, suggesting development of an intact reward-based working memory for recent stimulus values. Throughout the feedback epoch, individuals with autism spectrum disorders exhibited greater recruitment of the anterior cingulate and orbito-frontal cortices compared with individuals with typical development, indicating continuing trial-by-trial activity related to feedback processing. Conclusions Individuals with autism spectrum disorders exhibit learning deficits reflecting impaired ability to develop an effective reward-based working memory to guide stimulus selection. Instead, they continue to rely on trial-by-trial feedback processing to support learning dependent upon engagement of the anterior cingulate and orbito-frontal cortices. PMID:25158242

  17. INTERFEROMETRIC MONITORING OF GAMMA-RAY BRIGHT AGNs. I. THE RESULTS OF SINGLE-EPOCH MULTIFREQUENCY OBSERVATIONS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Sang-Sung; Wajima, Kiyoaki; Algaba, Juan-Carlos

    2016-11-01

    We present results of single-epoch very long baseline interferometry (VLBI) observations of gamma-ray bright active galactic nuclei (AGNs) using the Korean VLBI Network (KVN) at the 22, 43, 86, and 129 GHz bands, which are part of a KVN key science program, Interferometric Monitoring of Gamma-Ray Bright AGNs. We selected a total of 34 radio-loud AGNs of which 30 sources are gamma-ray bright AGNs with flux densities of >6 × 10{sup −10} ph cm{sup −2} s{sup −1}. Single-epoch multifrequency VLBI observations of the target sources were conducted during a 24 hr session on 2013 November 19 and 20. All observed sources weremore » detected and imaged at all frequency bands, with or without a frequency phase transfer technique, which enabled the imaging of 12 faint sources at 129 GHz, except for one source. Many of the target sources are resolved on milliarcsecond scales, yielding a core-jet structure, with the VLBI core dominating the synchrotron emission on a milliarcsecond scale. CLEAN flux densities of the target sources are 0.43–28 Jy, 0.32–21 Jy, 0.18–11 Jy, and 0.35–8.0 Jy in the 22, 43, 86, and 129 GHz bands, respectively. Spectra of the target sources become steeper at higher frequency, with spectral index means of −0.40, −0.62, and −1.00 in the 22–43 GHz, 43–86 GHz and 86–129 GHz bands, respectively, implying that the target sources become optically thin at higher frequencies (e.g., 86–129 GHz).« less

  18. In-flight automatic detection of vigilance states using a single EEG channel.

    PubMed

    Sauvet, F; Bougard, C; Coroenne, M; Lely, L; Van Beers, P; Elbaz, M; Guillard, M; Leger, D; Chennaoui, M

    2014-12-01

    Sleepiness and fatigue can reach particularly high levels during long-haul overnight flights. Under these conditions, voluntary or even involuntary sleep periods may occur, increasing the risk of accidents. The aim of this study was to assess the performance of an in-flight automatic detection system of low-vigilance states using a single electroencephalogram channel. Fourteen healthy pilots voluntarily wore a miniaturized brain electrical activity recording device during long-haul flights ( 10 ±2.0 h, Atlantic 2 and Falcon 50 M, French naval aviation). No subject was disturbed by the equipment. Seven pilots experienced at least a period of voluntary ( 26.8 ±8.0 min, n = 4) or involuntary sleep (N1 sleep stage, 26.6 ±18.7 s, n = 7) during the flight. Automatic classification (wake/sleep) by the algorithm was made for 10-s epochs (O1-M2 or C3-M2 channel), based on comparison of means to detect changes in α, β, and θ relative power, or ratio [( α+θ)/β], or fuzzy logic fusion (α, β). Pertinence and prognostic of the algorithm were determined using epoch-by-epoch comparison with visual-scoring (two blinded readers, AASM rules). The best concordance between automatic detection and visual-scoring was observed within the O1-M2 channel, using the ratio [( α+θ )/β] ( 98.3 ±4.1% of good detection, K = 0.94 ±0.07, with a 0.04 ±0.04 false positive rate and a 0.87 ±0.10 true positive rate). Our results confirm the efficiency of a miniaturized single electroencephalographic channel recording device, associated with an automatic detection algorithm, in order to detect low-vigilance states during real flights.

  19. Historical halo displays as past weather indicator

    NASA Astrophysics Data System (ADS)

    Neuhäuser, Dagmar; Neuhäuser, Ralph

    2017-04-01

    Certain halo displays like the 22° circle were known to indicate specific weather pattern since millennia - as specified in Babylonian omina, Aristotle's Meteorology, farmers' weather lore, etc. Today, it is known that halo phenomena are due to refraction and reflection of sun and moon light in ice crystals in cirrus and cirrostratus, so that halo observations do indicate atmospheric conditions like temperature, humidity, pressure etc. in a few km height. The Astronomical Diaries of Babylonia have recorded both halo phenomena (circles, parhelia, etc.) and weather conditions (rain, clouds, etc.), so that we can use them to show statistically, whether, which and how fast halo phenomena are related to weather - for the last few centuries BC for Babylonia. We can then also compare the observations of Babylonian priests in the given BC epoch (without air and light pollution) with the last few decades of the modern epoch (with air and light pollution), where amateur halo observers have systematically recorded such phenomena (in Europe). Weather and climate are known to be partly driven by solar activity. Hence, one could also consider whether there is an indirect relation between halo displays as weather proxy and aurorae as solar activity proxy - if low solar activity leads to low pressure systems, one could expect more halos, preliminary studies show such a hint. For the last few decades, we have many halo observations, satellite imaging of the aurora oval, and many data on solar activity. A statistically sufficient amount of aurora and halo observations should be available for the historic time to investigate such a possible connection: halos were recorded very often in antiquity and the medieval times (as found in chronicles etc.), and modern scholarly catalogs of aurorae also often contain unrecognized halo displays.

  20. Deciphering the Long-Term Trend of Atlantic Basin Intense Hurricanes: More Active Versus Less Active During the Present Epoch

    NASA Technical Reports Server (NTRS)

    Wilson, Robert M.

    1998-01-01

    During the interval of 1944-1997, 120 intense hurricanes (i.e., those of category 3 or higher on the Saffir-Simpson hurricane damage potential scale) were observed in the Atlantic basin, having an annual frequency of 0-7 events per year, being more active prior to the mid 1960's than thereafter (hence a possible two-state division: more active versus less active), and being preferentially lower during El Nino years as compared to non-El Nino years. Because decadal averages of the frequency of intense hurricanes closely resemble those of average temperature anomalies for northern hemispheric and global standards and of the average temperature at the Armagh Observatory (Northern Ireland), a proxy for climatic change, it is inferred that the long-term trends of the annual frequency of intense hurricanes and temperature may be statistically related. Indeed, on the basis of 4- and 10-yr moving averages, one finds that there exists strong linear associations between the annual frequency of intense hurricanes in the Atlantic basin and temperature (specially, when temperature slightly leads). Because the long-term leading trends of temperature are now decidedly upward, beginning about the mid 1980's, it is inferred that the long-term consequential trends of the annual frequency of intense hurricanes should now also be upward, having begun near 1990, suggesting that a return to the more active state probably has already occurred. However, because of the anomalous El Nino activity of the early to mid 1990's, the switch from the less active to the more active state essentially went unnoticed (a marked increase in the number of intense hurricanes was not observed until the 1995 and 1996 hurricane seasons, following the end of the anomalous El Nino activity). Presuming that a return to the more active state has, indeed, occurred, one expects the number of seasonal intense hurricanes during the present epoch (continuing through about 2012) to usually be higher than average (i.e., greater than or equal to 2), except during El Nino-related seasons when the number usually will be less than average.

  1. Survival and developmental disability in infants with birth weights of 501 to 800 grams, born between 1979 and 1994.

    PubMed

    O'Shea, T M; Klinepeter, K L; Goldstein, D J; Jackson, B W; Dillard, R G

    1997-12-01

    Because the survival rate has increased for extremely low birth weight neonates, many have raised the concern that the rate of developmental disability among survivors will also increase. To address this concern, we analyzed changes over time in survival and major neurosensory impairment in a sample of extremely low birth weight infants born between July 1, 1979, and June 30, 1994. The study sample included 513 infants with birth weights of 501 to 800 g who were cared for in either of the two neonatal intensive care units that serve a 17-county region in northwest North Carolina and who were born to mothers residing in that region. At 1 year of age (corrected for gestation), survivors were examined by a pediatrician and were tested using the Bayley Scales of Infant Development. Major neurosensory impairment was defined as cerebral palsy, a Bayley Mental Developmental Index <68, or blindness. A total of 209/216 (97%) of survivors were examined at 1 year of age. Epoch of birth was defined as follows: epoch 1, July 1, 1979 to June 30, 1984; epoch 2, July 1, 1984 to June 30, 1989; and epoch 3, July 1, 1989 to June 30, 1994. Survival rates for epochs 1, 2, and 3 were, respectively, 24/120 (20%), 63/175 (36%), and 129/218 (59%). In contrast, the proportions with a major neurosensory impairment did not increase over time; rates for successive epochs were 6/24 (25%), 17/61 (28%), and 26/124 (21%). Rates of cerebral palsy were 3/24 (13%), 12/61 (20%), and 9/124 (7%); rates of delayed mental development were 4/24 (17%), 12/61 (20%), and 17/124 (14%); and rates of blindness were 2/24 (8%), 0/62, and 5/124 (4%), respectively. This analysis suggests that the increasing survival of extremely low birth weight neonates since the late 1970s has not resulted in an increased rate of major developmental problems identifiable at 1 year of age.

  2. Neurobiology of Self-Awareness in Schizophrenia: an fMRI Study

    PubMed Central

    Shad, Mujeeb U.; Keshavan, Matcheri S.; Steinberg, Joel L.; Mihalakos, Perry; Thomas, Binu P.; Motes, Michael A.; Soares, Jair C.; Tamminga, Carol A.

    2012-01-01

    Self-awareness (SA) is one of the core domains of higher cortical functions and is frequently compromised in schizophrenia. Deficits in SA have been associated with functional and psychosocial impairment in this patient population. However, despite its clinical significance, only a few studies have examined the neural substrates of self-referential processing in schizophrenia. The aim of this study was to assess self-awareness in schizophrenia using a functional magnetic resonance imaging (fMRI) paradigm designed to elicit judgments of self-reference in a simulated social context. While scanned, volunteers looked at visually-displayed sentences that had the volunteer’s own first name (self-directed sentence-stimulus) or an unknown other person’s first name (other-directed sentence stimulus) as the grammatical subject of the sentence. The volunteers were asked to discern whether each sentence-stimulus was about the volunteer personally (during a self-referential cue epoch) or asked whether each statement was about someone else (during an other-referential cue epoch). We predicted that individuals with schizophrenia would demonstrate altered functional activation to self- and other-directed sentence-stimuli as compared to controls. Fifteen controls and seventeen schizophrenia volunteers completed clinical assessments and SA fMRI task on a 3T Philips 3.0 T Achieva system. The results showed significantly greater activation in schizophrenia compared to controls for cortical midline structures in response to self- vs. other-directed sentence-stimuli. These findings support results from earlier studies and demonstrate selective alteration in the activation of cortical midline structures associated with evaluations of self-reference in schizophrenia as compared to controls. PMID:22480958

  3. Neurobiology of self-awareness in schizophrenia: an fMRI study.

    PubMed

    Shad, Mujeeb U; Keshavan, Matcheri S; Steinberg, Joel L; Mihalakos, Perry; Thomas, Binu P; Motes, Michael A; Soares, Jair C; Tamminga, Carol A

    2012-07-01

    Self-awareness (SA) is one of the core domains of higher cortical functions and is frequently compromised in schizophrenia. Deficits in SA have been associated with functional and psychosocial impairment in this patient population. However, despite its clinical significance, only a few studies have examined the neural substrates of self-referential processing in schizophrenia. The aim of this study was to assess self-awareness in schizophrenia using a functional magnetic resonance imaging (fMRI) paradigm designed to elicit judgments of self-reference in a simulated social context. While scanned, volunteers looked at visually-displayed sentences that had the volunteer's own first name (self-directed sentence-stimulus) or an unknown other person's first name (other-directed sentence stimulus) as the grammatical subject of the sentence. The volunteers were asked to discern whether each sentence-stimulus was about the volunteer personally (during a self-referential cue epoch) or asked whether each statement was about someone else (during an other-referential cue epoch). We predicted that individuals with schizophrenia would demonstrate altered functional activation to self- and other-directed sentence-stimuli as compared to controls. Fifteen controls and seventeen schizophrenia volunteers completed clinical assessments and SA fMRI task on a 3T Philips 3.0 T Achieva system. The results showed significantly greater activation in schizophrenia compared to controls for cortical midline structures in response to self- vs. other-directed sentence-stimuli. These findings support results from earlier studies and demonstrate selective alteration in the activation of cortical midline structures associated with evaluations of self-reference in schizophrenia as compared to controls. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Accuracy of Automatic Polysomnography Scoring Using Frontal Electrodes

    PubMed Central

    Younes, Magdy; Younes, Mark; Giannouli, Eleni

    2016-01-01

    Study Objectives: The economic cost of performing sleep monitoring at home is a major deterrent to adding sleep data during home studies for investigation of sleep apnea and to investigating non-respiratory sleep complaints. Michele Sleep Scoring System (MSS) is a validated automatic system that utilizes central electroencephalography (EEG) derivations and requires minimal editing. We wished to determine if MSS' accuracy is maintained if frontal derivations are used instead. If confirmed, home sleep monitoring would not require home setup or lengthy manual scoring by technologists. Methods: One hundred two polysomnograms (PSGs) previously recorded from patients with assorted sleep disorders were scored using MSS once with central and once with frontal derivations. Total sleep time, sleep/stage R sleep onset latencies, awake time, time in different sleep stages, arousal/awakening index and apnea-hypopnea index were compared. In addition, odds ratio product (ORP), a continuous index of sleep depth/quality (Sleep 2015;38:641–54), was generated for every 30-sec epoch in each PSG and epoch-by-epoch comparison of ORP was performed. Results: Intraclass correlation coefficients (ICCs) ranged from 0.89 to 1.0 for the various sleep variables (0.96 ± 0.03). For epoch-by-epoch comparisons of ORP, ICC was > 0.85 in 96 PSGs. Lower values in the other six PSGs were related to signal artifacts in either derivation. ICC for whole-record average ORP was 0.98. Conclusions: MSS is as accurate with frontal as with central EEG derivations. The use of frontal electrodes along with MSS should make it possible to obtain high-quality sleep data without requiring home setup or lengthy scoring time by expert technologists. Citation: Younes M, Younes M, Giannouli E. Accuracy of automatic polysomnography scoring using frontal electrodes. J Clin Sleep Med 2016;12(5):735–746. PMID:26951417

  5. A comparison of video review and feedback device measurement of chest compressions quality during pediatric cardiopulmonary resuscitation.

    PubMed

    Hsieh, Ting-Chang; Wolfe, Heather; Sutton, Robert; Myers, Sage; Nadkarni, Vinay; Donoghue, Aaron

    2015-08-01

    To describe chest compression (CC) rate, depth, and leaning during pediatric cardiopulmonary resuscitation (CPR) as measured by two simultaneous methods, and to assess the accuracy and reliability of video review in measuring CC quality. Resuscitations in a pediatric emergency department are videorecorded for quality improvement. Patients aged 8-18 years receiving CPR under videorecording were eligible for inclusion. CPR was recorded by a pressure/accelerometer feedback device and tabulated in 30-s epochs of uninterrupted CC. Investigators reviewed videorecorded CPR and measured rate, depth, and release by observation. Raters categorized epochs as 'meeting criteria' if 80% of CCs in an epoch were done with appropriate depth (>45 mm) and/or release (<2.5 kg leaning). Comparison between device measurement and video was made by Spearman's ρ for rate and by κ statistic for depth and release. Interrater reliability for depth and release was measured by κ statistic. Five patients underwent videorecorded CPR using the feedback device. 97 30-s epochs of CCs were analyzed. CCs met criteria for rate in 74/97 (76%) of epochs; depth in 38/97 (39%); release in 82/97 (84%). Agreement between video and feedback device for rate was good (ρ = 0.77); agreement was poor for depth and release (κ 0.04-0.41). Interrater reliability for depth and release measured by video was poor (κ 0.04-0.49). Video review measured CC rate accurately; depth and release were not reliably or accurately assessed by video. Future research should focus on the optimal combination of methods for measuring CPR quality. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  6. A search for changing look quasars in second epoch imaging

    NASA Astrophysics Data System (ADS)

    Findlay, Joseph; Myers, Adam; McGreer, Ian

    2018-01-01

    Over nearly two decades, the Sloan Digital Sky Survey has compiled a catalog of over half a million confirmed quasars. During that period approximately ten percent of these objects have been spectroscopically observed in two or more epochs over baselines of ten or more years. This led recently to the discovery of the largest change in luminosity ever before observed in a quasar. The dimming emission was a reflection of very significant changes in continuum and broad line properties, the source had effectively transitioned from a Type I quasar to a Type II AGN. Since then several more "changing look" quasars have been discovered in multi-epoch SDSS spectroscopy. Among them are objects with rising and falling luminosities, appearing and disappearing broad lines. The origin of this behavior is still very uncertain, currently favored is the scenario in which an accreting black hole is simply starved of fuel. Other plausible scenarios include flaring due to stellar tidal disruption close to the black hole or large changes in accretion flow, which can occur during transitions between radiatively efficient and inefficient accretion regimes. Monitoring of larger numbers of changing look quasars will help to elucidate these ideas.In this poster, we report on the progress of a pilot study in which we hope to learn how to select changing look quasars in multi-epoch imaging. This will allow us to take advantage of the entire SDSS quasar catalog rather than just the ten percent of objects with multi-epoch spectroscopy. Comparing archival SDSS and more recent Legacy Survey imaging over ten-year baselines we select objects whose photometry is consistent with the large changes in luminosity expected in changing look quasars. We aim to build up a catalog of both transitioned and transitioning objects for future monitoring.

  7. Extragalactic optical and near-infrared foregrounds to 21-cm epoch of reionisation experiments

    NASA Astrophysics Data System (ADS)

    Jarvis, Matt J.; Bowler, Rebecca A. A.; Hatfield, Peter W.

    2018-05-01

    Foreground contamination is one of the most important limiting factors in detecting the neutral hydrogen in the epoch of reionisation. These foregrounds can be roughly split into galactic and extragalactic foregrounds. In these proceedings we highlight information that can be gleaned from multi-wavelength extragalactic surveys in order to overcome this issue. We discuss how clustering information from the lower-redshift, foreground galaxies, can be used as additional information in accounting for the noise associated with the foregrounds. We then go on to highlight the expected contribution of future optical and near-infrared surveys for detecting the galaxies responsible for ionising the Universe. We suggest that these galaxies can also be used to reduce the systematics in the 21-cm epoch of reionisation signal through cross-correlations if enough common area is surveyed.

  8. Multi-epoch BVRI Photometry of Luminous Stars in M31 and M33

    NASA Astrophysics Data System (ADS)

    Martin, John C.; Humphreys, Roberta M.

    2017-09-01

    We present the first four years of BVRI photometry from an on-going survey to annually monitor the photometric behavior of evolved luminous stars in M31 and M33. Photometry was measured for 199 stars at multiple epochs, including 9 classic Luminous Blue Variables (LBVs), 22 LBV candidates, 10 post-RGB A/F type hypergiants, and 18 B[e] supergiants. At all epochs, the brightness is measured in the V-band and at least one other band to a precision of 0.04-0.10 mag down to a limiting magnitude of 19.0-19.5. Thirty three stars in our survey exhibit significant variability, including at least two classic LBVs caught in S Doradus-type outbursts. A hyperlinked version of the photometry catalog is at http://go.uis.edu/m31m33photcat.

  9. The Anthropocene: A Planetary Perspective

    NASA Astrophysics Data System (ADS)

    Anbar, A. D.; Hartnett, H. E.; York, A.; Selin, C.

    2016-12-01

    The Anthropocene is a new planetary epoch defined by the emergence of human activity as one of the most important driving forces on Earth, rivaling and also stressing the other systems that govern the planet's habitability. Public discussions and debates about the challenges of this epoch tend to be polarized. One extreme denies that humans have a planetary-scale impact, while the other wishes that this impact could disappear. The tension between these perspectives is often paralyzing. Effective adaptation and mitigation requires a new perspective that reframes the conversation. We propose a planetary perspective according to which this epoch is the result of a recent major innovation in the 4 ­billion ­year history of life on Earth: the emergence of an energy-intensive planetary civilization. The rate of human energy use is already within an order of magnitude of that of the rest of the biosphere, and rising rapidly, and so this innovation is second only to the evolution of photosynthesis in terms of energy capture and utilization by living systems. Such energy use has and will continue to affect Earth at planetary scale. This reality cannot be denied nor wished away. From this pragmatic perspective, the Anthropocene is not an unnatural event that can be reversed, as though humanity is separate from the Earth systems with which we are co-evolving. Rather, it is an evolutionary transition to be managed. This is the challenge of turning a carelessly altered planet into a carefully designed and managed world, maintaining a "safe operating space" for human civilization (Steffen et al., 2011). To do so, we need an integrated approach to Earth systems science that considers humans as a natural and integral component of Earth's systems. Insights drawn from the humanities and the social sciences must be integrated with the natural sciences in order to thrive in this new epoch. This type of integrated perspective is relatively uncontroversial on personal, local, and even regional scales. It is, however, intimidating at the global scale, for good reason: it is a daunting challenge that we barely understand and for which we are poorly prepared. In this presentation, we will address approaches to adaptation and mitigation that illustrate the promise - and pitfalls - of a planetary design perspective relevant to food, energy, water, and climate.

  10. Defining the Anthropocene

    NASA Astrophysics Data System (ADS)

    Lewis, Simon; Maslin, Mark

    2016-04-01

    Time is divided by geologists according to marked shifts in Earth's state. Recent global environmental changes suggest that Earth may have entered a new human-dominated geological epoch, the Anthropocene. Should the Anthropocene - the idea that human activity is a force acting upon the Earth system in ways that mean that Earth will be altered for millions of years - be defined as a geological time-unit at the level of an Epoch? Here we appraise the data to assess such claims, first in terms of changes to the Earth system, with particular focus on very long-lived impacts, as Epochs typically last millions of years. Can Earth really be said to be in transition from one state to another? Secondly, we then consider the formal criteria used to define geological time-units and move forward through time examining whether currently available evidence passes typical geological time-unit evidence thresholds. We suggest two time periods likely fit the criteria (1) the aftermath of the interlinking of the Old and New Worlds, which moved species across continents and ocean basins worldwide, a geologically unprecedented and permanent change, which is also the globally synchronous coolest part of the Little Ice Age (in Earth system terms), and the beginning of global trade and a new socio-economic "world system" (in historical terms), marked as a golden spike by a temporary drop in atmospheric CO2, centred on 1610 CE; and (2) the aftermath of the Second World War, when many global environmental changes accelerated and novel long-lived materials were increasingly manufactured, known as the Great Acceleration (in Earth system terms) and the beginning of the Cold War (in historical terms), marked as a golden spike by the peak in radionuclide fallout in 1964. We finish by noting that the Anthropocene debate is politically loaded, thus transparency in the presentation of evidence is essential if a formal definition of the Anthropocene is to avoid becoming a debate about bias. The Anthropocene is essentially the time when human history meshes with near-permanent changes to the Earth system and some of those changes are preserved as geological deposits. A satisfying theory and definition of the Anthropocene will ideally rest on intertwined evidence from disparate human history and natural science disciplines. Such a definition may not be possible, and different disciplines many utilise different definitions. However, any scientific definition of the Anthropocene Epoch should be transparently evidence-based.

  11. Deciphering Solar Magnetic Activity: On Grand Minima in Solar Activity

    NASA Astrophysics Data System (ADS)

    Mcintosh, Scott; Leamon, Robert

    2015-07-01

    The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well understood. There has been tremendous progress in the century since the discovery of solar magnetism - magnetism that ultimately drives the electromagnetic, particulate and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a "grand minimum"? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(-ish) year solar activity cycle.

  12. Minimum Risk Pesticides - Inert Ingredient and Active Ingredient Eligibility under 40 CFR 152.25(f)

    EPA Pesticide Factsheets

    Ingredients found on both the Minimum Risk Active Ingredient and List 4A Inert Ingredients of Minimal Concern lists may be used either as an active or an inert ingredient. Otherwise, it can only be used based on the list it appears on.

  13. The 1992 activities of the International GPS Geodynamics Service (IGS).

    NASA Astrophysics Data System (ADS)

    Beutler, G.

    The primary goal of the International GPS Geodynamics Service (IGS) is to give the scientific community high quality GPS orbits (and related information like earth orientation parameters) to perform regional or local GPS analyses without further orbit improvement. The declared goal of the three month 1992 IGS Test Campaign was the routine production of accurate GPS orbits using the observations of about 30 globally distributed IGS Core Sites. IGS Epoch Campaigns will be organized about every second year.

  14. Omega VLF timing revision 1

    NASA Technical Reports Server (NTRS)

    Swanson, E. R.; Kugel, C. P.

    1972-01-01

    The report specifically discusses time dissemination techniques, including epoch determination, frequency determination, and ambiguity resolution. It also discusses operational considerations including equipment, path selection, and adjustment procedure. epoch (the actual location or timing of periodic events) is shown to be both maintainable and calibratable by the techniques described to better than 3-microsecond accuracy; and frequency (the uniformity of the time scale) to about one part in 10 to the 12th power.

  15. Observing the epoch of galaxy formation.

    PubMed

    Steidel, C C

    1999-04-13

    Significant observational progress in addressing the question of the origin and early evolution of galaxies has been made in the past few years, allowing for direct comparison of the epoch when most of the stars in the universe were forming to prevailing theoretical models. There is currently broad consistency between theoretical expectations and the observations, but rapid improvement in the data will provide much more critical tests of theory in the coming years.

  16. Electro-oculography-based detection of sleep-wake in sleep apnea patients.

    PubMed

    Virkkala, Jussi; Toppila, Jussi; Maasilta, Paula; Bachour, Adel

    2015-09-01

    Recently, we have developed a simple method that uses two electro-oculography (EOG) electrodes for the automatic scoring of sleep-wake in normal subjects. In this study, we investigated the usefulness of this method on 284 consecutive patients referred for a suspicion of sleep apnea who underwent a polysomnography (PSG). We applied the AASM 2007 scoring rules. A simple automatic sleep-wake classification algorithm based on 18-45 Hz beta power was applied to the calculated bipolar EOG channel and was compared to standard polysomnography. Epoch by epoch agreement was evaluated. Eighteen patients were excluded due to poor EOG quality. One hundred fifty-eight males and 108 females were studied, their mean age was 48 (range 17-89) years, apnea-hypopnea index 13 (range 0-96) /h, BMI 29 (range 17-52) kg/m(2), and sleep efficiency 78 (range 0-98) %. The mean agreement in sleep-wake states between EOG and PSG was 85% and the Cohen's kappa was 0.56. Overall epoch-by-epoch agreement was 85%, and the Cohen's kappa was 0.57 with positive predictive value of 91% and negative predictive value of 65%. The EOG method can be applied to patients referred for suspicion of sleep apnea to indicate the sleep-wake state.

  17. A 2 epoch proper motion catalogue from the UKIDSS Large Area Survey

    NASA Astrophysics Data System (ADS)

    Smith, Leigh; Lucas, Phil; Burningham, Ben; Jones, Hugh; Pinfield, David; Smart, Ricky; Andrei, Alexandre

    2013-04-01

    The UKIDSS Large Area Survey (LAS) began in 2005, with the start of the UKIDSS program as a 7 year effort to survey roughly 4000 square degrees at high galactic latitudes in Y, J, H and K bands. The survey also included a significant quantity of 2-epoch J band observations, with epoch baselines ranging from 2 to 7 years. We present a proper motion catalogue for the 1500 square degrees of the 2 epoch LAS data, which includes some 800,000 sources with motions detected above the 5σ level. We developed a bespoke proper motion pipeline which applies a source-unique second order polynomial transformation to UKIDSS array coordinates of each source to counter potential local non-uniformity in the focal plane. Our catalogue agrees well with the proper motion data supplied in the current WFCAM Science Archive (WSA) DR9 catalogue where there is overlap, and in various optical catalogues, but it benefits from some improvements. One improvement is that we provide absolute proper motions, using LAS galaxies for the relative to absolute correction. Also, by using unique, local, 2nd order polynomial tranformations, as opposed to the linear transformations in the WSA, we correct better for any local distortions in the focal plane, not including the radial distortion that is removed by their pipeline.

  18. ENSO shifts and their link to Southern Africa surface air temperature in summer

    NASA Astrophysics Data System (ADS)

    Manatsa, D.; Mukwada, G.; Makaba, L.

    2018-05-01

    ENSO has been known to influence the trends of summer warming over Southern Africa. In this work, we used observational and reanalysis data to analyze the relationship between ENSO and maximum surface air temperature (SATmax) trends during the three epochs created by the ENSO phase shifts around 1977 and 1997 for the period 1960 to 2014. We observed that while ENSO and cloud cover remains the dominant factor controlling SATmax variability, the first two epochs had the predominant La Niña (El Niño)-like events connected to robust positive (negative) trends in cloud fraction. However, this established relationship reversed in the post-1997 La Niña-like dominated epoch which coincided with a falling cloud cover trend. It is established that this deviation from the previously established link within the previous epochs could be due to the post-1998 era in which SATmin was suppressed while SATmax was enhanced. The resulting increase in diurnal temperature range (DTR) could have discouraged the formation of low-level clouds which have relatively more extensive areal coverage and hence allowing more solar energy to reach the surface to boost daytime SATmax. It is noted that these relationships are more pronounced from December to March.

  19. Implementation of health information technology to maximize efficiency of resource utilization in a geographically dispersed prenatal care delivery system.

    PubMed

    Cochran, Marlo Baker; Snyder, Russell R; Thomas, Elizabeth; Freeman, Daniel H; Hankins, Gary D V

    2012-04-01

    This study investigated the utilization of health information technology (HIT) to enhance resource utilization in a geographically dispersed tertiary care system with extensive outpatient and delivery services. It was initiated as a result of a systems change implemented after Hurricane Ike devastated southeast Texas. A retrospective database and electronic medical record review was performed, which included data collection from all patients evaluated 18 months prior (epoch I) and 18 months following (epoch II) the landfall of Hurricane Ike. The months immediately following the storm were omitted from the analysis, allowing time to establish a new baseline. We analyzed a total of 21,201 patients evaluated in triage at the University of Texas Medical Branch. Epoch I consisted of 11,280 patients and epoch II consisted of 9922 patients. Using HIT, we were able to decrease the number of visits to triage while simultaneously managing more complex patients in the outpatient setting with no clinically significant change in maternal or fetal outcome. This study developed an innovated model of care using constrained resources while providing quality and safety to our patients without additional cost to the health care delivery system. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  20. Sunspot variation and selected associated phenomena: A look at solar cycle 21 and beyond

    NASA Technical Reports Server (NTRS)

    Wilson, R. M.

    1982-01-01

    Solar sunspot cycles 8 through 21 are reviewed. Mean time intervals are calculated for maximum to maximum, minimum to minimum, minimum to maximum, and maximum to minimum phases for cycles 8 through 20 and 8 through 21. Simple cosine functions with a period of 132 years are compared to, and found to be representative of, the variation of smoothed sunspot numbers at solar maximum and minimum. A comparison of cycles 20 and 21 is given, leading to a projection for activity levels during the Spacelab 2 era (tentatively, November 1984). A prediction is made for cycle 22. Major flares are observed to peak several months subsequent to the solar maximum during cycle 21 and to be at minimum level several months after the solar minimum. Additional remarks are given for flares, gradual rise and fall radio events and 2800 MHz radio emission. Certain solar activity parameters, especially as they relate to the near term Spacelab 2 time frame are estimated.

  1. The ultraviolet-bright, slowly declining transient PS1-11af as a partial tidal disruption event

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chornock, R.; Berger, E.; Zauderer, B. A.

    2014-01-01

    We present the Pan-STARRS1 discovery of the long-lived and blue transient PS1-11af, which was also detected by Galaxy Evolution Explorer with coordinated observations in the near-ultraviolet (NUV) band. PS1-11af is associated with the nucleus of an early type galaxy at redshift z = 0.4046 that exhibits no evidence for star formation or active galactic nucleus activity. Four epochs of spectroscopy reveal a pair of transient broad absorption features in the UV on otherwise featureless spectra. Despite the superficial similarity of these features to P-Cygni absorptions of supernovae (SNe), we conclude that PS1-11af is not consistent with the properties of knownmore » types of SNe. Blackbody fits to the spectral energy distribution are inconsistent with the cooling, expanding ejecta of a SN, and the velocities of the absorption features are too high to represent material in homologous expansion near a SN photosphere. However, the constant blue colors and slow evolution of the luminosity are similar to previous optically selected tidal disruption events (TDEs). The shape of the optical light curve is consistent with models for TDEs, but the minimum accreted mass necessary to power the observed luminosity is only ∼0.002 M {sub ☉}, which points to a partial disruption model. A full disruption model predicts higher bolometric luminosities, which would require most of the radiation to be emitted in a separate component at high energies where we lack observations. In addition, the observed temperature is lower than that predicted by pure accretion disk models for TDEs and requires reprocessing to a constant, lower temperature. Three deep non-detections in the radio with the Very Large Array over the first two years after the event set strict limits on the production of any relativistic outflow comparable to Swift J1644+57, even if off-axis.« less

  2. Using multiple linear regression model to estimate thunderstorm activity

    NASA Astrophysics Data System (ADS)

    Suparta, W.; Putro, W. S.

    2017-03-01

    This paper is aimed to develop a numerical model with the use of a nonlinear model to estimate the thunderstorm activity. Meteorological data such as Pressure (P), Temperature (T), Relative Humidity (H), cloud (C), Precipitable Water Vapor (PWV), and precipitation on a daily basis were used in the proposed method. The model was constructed with six configurations of input and one target output. The output tested in this work is the thunderstorm event when one-year data is used. Results showed that the model works well in estimating thunderstorm activities with the maximum epoch reaching 1000 iterations and the percent error was found below 50%. The model also found that the thunderstorm activities in May and October are detected higher than the other months due to the inter-monsoon season.

  3. Renewed Radio Activity of Age 370 years in the Extragalactic Source 0108+388

    NASA Astrophysics Data System (ADS)

    Owsianik, I.; Conway, J. E.; Polatidis, A. G.

    1998-08-01

    We present the results of multi-epoch global VLBI observations of the Compact Symmetric Object (CSO) 0108+388 at 5 GHz. Analysis of data spread over 12 years shows strong evidence for an increase in the separation of the outer components at a rate of 0.197+/-0.026 h(-1) c. Given an overall size of 22.2 h(-1) pc this implies a kinematic age of only 367+/-48 yrs. This result strongly supports the idea that radio emission in Compact Symmetric Objects arises from recently activated radio sources. The presence of weak radio emission on kpc-scales in 0108+388 suggests recurrent activity in this source, and that we are observing it just as a new period of activity is beginning.

  4. Strong earthquakes, novae and cosmic ray environment

    NASA Technical Reports Server (NTRS)

    Yu, Z. D.

    1985-01-01

    Observations about the relationship between seismic activity and astronomical phenomena are discussed. First, after investigating the seismic data (magnitude 7.0 and over) with the method of superposed epochs it is found that world seismicity evidently increased after the occurring of novae with apparent magnitude brighter than 2.2. Second, a great many earthquakes of magnitude 7.0 and over occurred in the 13th month after two of the largest ground level solar cosmic ray events (GLEs). The causes of three high level phenomena of global seismic activity in 1918-1965 can be related to these, and it is suggested that according to the information of large GLE or bright nova predictions of the times of global intense seismic activity can be made.

  5. 29 CFR 510.23 - Agricultural activities eligible for minimum wage phase-in.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Agricultural activities eligible for minimum wage phase-in. 510.23 Section 510.23 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... FAIR LABOR STANDARDS ACT IN PUERTO RICO Classification of Industries § 510.23 Agricultural activities...

  6. Report on the Photometric Observations of the Variable Stars DH Pegasi, DY Pegasi, and RZ Cephei

    NASA Astrophysics Data System (ADS)

    Abu-Sharkh, I.; Fang, S.; Mehta, S.; Pham, D.

    2014-12-01

    We report 872 observations on two RR Lyrae variable stars, DH Pegasi and RZ Cephei, and on one SX Phoenicis variable, DY Pegasi. This paper discusses the methodology of our measurements, the light curves, magnitudes, epochs, and epoch prediction of the above stars. We also derived the period of DY Pegasi. All measurements and analyses are compared with prior publications and known values from multiple databases.

  7. Observing the epoch of galaxy formation

    PubMed Central

    Steidel, Charles C.

    1999-01-01

    Significant observational progress in addressing the question of the origin and early evolution of galaxies has been made in the past few years, allowing for direct comparison of the epoch when most of the stars in the universe were forming to prevailing theoretical models. There is currently broad consistency between theoretical expectations and the observations, but rapid improvement in the data will provide much more critical tests of theory in the coming years. PMID:10200244

  8. Multi-epoch analysis of the X-ray spectrum of the active galactic nucleus in NGC 5506

    NASA Astrophysics Data System (ADS)

    Sun, Shangyu; Guainazzi, Matteo; Ni, Qingling; Wang, Jingchun; Qian, Chenyang; Shi, Fangzheng; Wang, Yu; Bambi, Cosimo

    2018-05-01

    We present a multi-epoch X-ray spectroscopy analysis of the nearby narrow-line Seyfert I galaxy NGC 5506. For the first time, spectra taken by Chandra, XMM-Newton, Suzaku, and NuSTAR - covering the 2000-2014 time span - are analyzed simultaneously, using state-of-the-art models to describe reprocessing of the primary continuum by optical thick matter in the AGN environment. The main goal of our study is determining the spin of the supermassive black hole (SMBH). The nuclear X-ray spectrum is photoelectrically absorbed by matter with column density ≃ 3 × 1022 cm-2. A soft excess is present at energies lower than the photoelectric cut-off. Both photo-ionized and collisionally ionized components are required to fit it. This component is constant over the time-scales probed by our data. The spectrum at energies higher than 2 keV is variable. We propose that its evolution could be driven by flux-dependent changes in the geometry of the innermost regions of the accretion disk. The black hole spin in NGC ,5506 is constrained to be 0.93± _{ 0.04 }^{0.04} at 90% confidence level for one interesting parameter.

  9. Stratigraphic and Earth System approaches to defining the Anthropocene

    NASA Astrophysics Data System (ADS)

    Steffen, Will; Leinfelder, Reinhold; Zalasiewicz, Jan; Waters, Colin N.; Williams, Mark; Summerhayes, Colin; Barnosky, Anthony D.; Cearreta, Alejandro; Crutzen, Paul; Edgeworth, Matt; Ellis, Erle C.; Fairchild, Ian J.; Galuszka, Agnieszka; Grinevald, Jacques; Haywood, Alan; Ivar do Sul, Juliana; Jeandel, Catherine; McNeill, J. R.; Odada, Eric; Oreskes, Naomi; Revkin, Andrew; Richter, Daniel deB.; Syvitski, James; Vidas, Davor; Wagreich, Michael; Wing, Scott L.; Wolfe, Alexander P.; Schellnhuber, H. J.

    2016-08-01

    Stratigraphy provides insights into the evolution and dynamics of the Earth System over its long history. With recent developments in Earth System science, changes in Earth System dynamics can now be observed directly and projected into the near future. An integration of the two approaches provides powerful insights into the nature and significance of contemporary changes to Earth. From both perspectives, the Earth has been pushed out of the Holocene Epoch by human activities, with the mid-20th century a strong candidate for the start date of the Anthropocene, the proposed new epoch in Earth history. Here we explore two contrasting scenarios for the future of the Anthropocene, recognizing that the Earth System has already undergone a substantial transition away from the Holocene state. A rapid shift of societies toward the UN Sustainable Development Goals could stabilize the Earth System in a state with more intense interglacial conditions than in the late Quaternary climate regime and with little further biospheric change. In contrast, a continuation of the present Anthropocene trajectory of growing human pressures will likely lead to biotic impoverishment and a much warmer climate with a significant loss of polar ice.

  10. Influence of geomagnetic activity and atmospheric pressure in hypertensive adults.

    PubMed

    Azcárate, T; Mendoza, B

    2017-09-01

    We performed a study of the systolic and diastolic arterial blood pressure behavior under natural variables such as the atmospheric pressure and the horizontal geomagnetic field component. We worked with a group of eight adult hypertensive volunteers, four men and four women, with ages between 18 and 27 years in Mexico City during a geomagnetic storm in 2014. The data was divided by gender, age, and day/night cycle. We studied the time series using three methods: correlations, bivariate analysis, and superposed epoch (within a window of 2 days around the day of occurrence of a geomagnetic storm) analysis, between the systolic and diastolic blood pressure and the natural variables. The correlation analysis indicated a correlation between the systolic and diastolic blood pressure and the atmospheric pressure and the horizontal geomagnetic field component, being the largest during the night. Furthermore, the correlation and bivariate analyses showed that the largest correlations are between the systolic and diastolic blood pressure and the horizontal geomagnetic field component. Finally, the superposed epoch analysis showed that the largest number of significant changes in the blood pressure under the influence of geomagnetic field occurred in the systolic blood pressure for men.

  11. Influence of geomagnetic activity and atmospheric pressure in hypertensive adults

    NASA Astrophysics Data System (ADS)

    Azcárate, T.; Mendoza, B.

    2017-09-01

    We performed a study of the systolic and diastolic arterial blood pressure behavior under natural variables such as the atmospheric pressure and the horizontal geomagnetic field component. We worked with a group of eight adult hypertensive volunteers, four men and four women, with ages between 18 and 27 years in Mexico City during a geomagnetic storm in 2014. The data was divided by gender, age, and day/night cycle. We studied the time series using three methods: correlations, bivariate analysis, and superposed epoch (within a window of 2 days around the day of occurrence of a geomagnetic storm) analysis, between the systolic and diastolic blood pressure and the natural variables. The correlation analysis indicated a correlation between the systolic and diastolic blood pressure and the atmospheric pressure and the horizontal geomagnetic field component, being the largest during the night. Furthermore, the correlation and bivariate analyses showed that the largest correlations are between the systolic and diastolic blood pressure and the horizontal geomagnetic field component. Finally, the superposed epoch analysis showed that the largest number of significant changes in the blood pressure under the influence of geomagnetic field occurred in the systolic blood pressure for men.

  12. Quasar Feedback at the Peak of the Galaxy Formation Epoch

    NASA Astrophysics Data System (ADS)

    Liu, Guilin; Zakamska, Nadia L.; Strauss, Michael A.; Greene, Jenny E.; Alexandroff, Rachael

    2014-08-01

    The correlations between properties of supermassive black holes and stellar spheroids in galaxies imply a physical connection between these two components. Using Gemini GMOS IFU, we demonstrated that powerful ionized gas winds are ubiquitous in luminous radio-quiet z~ 0.5 quasars. We now extend this study to the era of peak galaxy formation and quasar activity when quasar feedback likely shaped the properties of massive galaxies. Our GMOS IFU observations of 5 quasars at z~ 3 are now underway, and we plan for fall observations. We propose a GMOS IFU survey to map the spatial distribution and kinematics of Ly(alpha) and N V 1240Aemission around 5 obscured quasars at z=3-3.3 that are extremely luminous (L_Ly(alpha)~10^45 erg s^- 1). Obscured quasars likely constitute the majority of the quasar population and represent the early enshrouded phase of black hole growth, luminous obscured quasars are thus the most likely sites of quasar feedback, as we found at low redshifts. We will look for quasar- driven outflows, and directly probe the effects of quasars on their galaxy-wide and intergalactic environments close to the peak of the galaxy formation epoch.

  13. VizieR Online Data Catalog: Proper motions and photometry of stars in NGC 3201 (Sariya+, 2017)

    NASA Astrophysics Data System (ADS)

    Sariya, D. P.; Jiang, I.-G.; Yadav, R. K. S.

    2017-07-01

    To determine the PMs of the stars in this work, we used archive images (http://archive.eso.org/eso/esoarchivemain.html) from observations made with the 2.2m ESO/MPI telescope at La Silla, Chile. This telescope contains a mosaic camera called the Wide-Field Imager (WFI), consisting of 4*2 (i.e., 8 CCD chips). Since each CCD has an array of 2048*4096 pixels, WFI ultimately produces images with a 34*33arcmin2 field of view. The observational run of the first epoch contains two images in B,V and I bands, each with 240s exposure time observed on 1999 December 05. In the second epoch, we have 35 images with 40s exposure time each in V filter observed during the period of 2014 April 02-05. Thus the epoch gap between the data is ~14.3 years. (2 data files).

  14. Geomagnetic polarity epochs: Nunivak Island, Alaska

    USGS Publications Warehouse

    Cox, A.; Dalrymple, G.B.

    1967-01-01

    New paleomagnetic and potassium-argon dating measurements have been made of basalt flows from Nunivak Island, Alaska, with the following results. (1) The best estimate of the age of the Brunhes/Matuyama polarity epoch boundary is found to be 0.694 m.y. (2) The best estimate of the age of the Gauss/Gilbert boundary is 3.32 m.y. (3) Three normally magnetized flows with ages from 0.93 to 0.88 m.y. are in accord with previous estimates of the age and duration of the Jaramillo normal event. (4) One normally magnetized flow with an age of 1.65 ?? 0.09 m.y. supplies additional evidence for the Gilsa?? normal event. (5) Two new normal events are identified within the Gilbert reversed epoch, the "Cochiti normal event" with an age of 3.7 m.y. and the "Nunivak normal event" with an age of 4.1 m.y. ?? 1967.

  15. Sequential Probability Ratio Test for Collision Avoidance Maneuver Decisions Based on a Bank of Norm-Inequality-Constrained Epoch-State Filters

    NASA Technical Reports Server (NTRS)

    Carpenter, J. R.; Markley, F. L.; Alfriend, K. T.; Wright, C.; Arcido, J.

    2011-01-01

    Sequential probability ratio tests explicitly allow decision makers to incorporate false alarm and missed detection risks, and are potentially less sensitive to modeling errors than a procedure that relies solely on a probability of collision threshold. Recent work on constrained Kalman filtering has suggested an approach to formulating such a test for collision avoidance maneuver decisions: a filter bank with two norm-inequality-constrained epoch-state extended Kalman filters. One filter models 1he null hypothesis 1ha1 the miss distance is inside the combined hard body radius at the predicted time of closest approach, and one filter models the alternative hypothesis. The epoch-state filter developed for this method explicitly accounts for any process noise present in the system. The method appears to work well using a realistic example based on an upcoming highly-elliptical orbit formation flying mission.

  16. Generalized Galileons: instabilities of bouncing and Genesis cosmologies and modified Genesis

    NASA Astrophysics Data System (ADS)

    Libanov, M.; Mironov, S.; Rubakov, V.

    2016-08-01

    We study spatially flat bouncing cosmologies and models with the early-time Genesis epoch in a popular class of generalized Galileon theories. We ask whether there exist solutions of these types which are free of gradient and ghost instabilities. We find that irrespectively of the forms of the Lagrangian functions, the bouncing models either are plagued with these instabilities or have singularities. The same result holds for the original Genesis model and its variants in which the scale factor tends to a constant as t → -∞. The result remains valid in theories with additional matter that obeys the Null Energy Condition and interacts with the Galileon only gravitationally. We propose a modified Genesis model which evades our no-go argument and give an explicit example of healthy cosmology that connects the modified Genesis epoch with kination (the epoch still driven by the Galileon field, which is a conventional massless scalar field at that stage).

  17. Integrated Change Detection and Classification in Urban Areas Based on Airborne Laser Scanning Point Clouds.

    PubMed

    Tran, Thi Huong Giang; Ressl, Camillo; Pfeifer, Norbert

    2018-02-03

    This paper suggests a new approach for change detection (CD) in 3D point clouds. It combines classification and CD in one step using machine learning. The point cloud data of both epochs are merged for computing features of four types: features describing the point distribution, a feature relating to relative terrain elevation, features specific for the multi-target capability of laser scanning, and features combining the point clouds of both epochs to identify the change. All these features are merged in the points and then training samples are acquired to create the model for supervised classification, which is then applied to the whole study area. The final results reach an overall accuracy of over 90% for both epochs of eight classes: lost tree, new tree, lost building, new building, changed ground, unchanged building, unchanged tree, and unchanged ground.

  18. A unified universe

    NASA Astrophysics Data System (ADS)

    Codello, Alessandro; Jain, Rajeev Kumar

    2018-05-01

    We present a unified evolution of the universe from very early times until the present epoch by including both the leading local correction R^2 and the leading non-local term R1/\\square ^2R to the classical gravitational action. We find that the inflationary phase driven by R^2 term gracefully exits in a transitory regime characterized by coherent oscillations of the Hubble parameter. The universe then naturally enters into a radiation dominated epoch followed by a matter dominated era. At sufficiently late times after radiation-matter equality, the non-local term starts to dominate inducing an accelerated expansion of the universe at the present epoch. We further exhibit the fact that both the leading local and non-local terms can be obtained within the covariant effective field theory of gravity. This scenario thus provides a unified picture of inflation and dark energy in a single framework by means of a purely gravitational action without the usual need of a scalar field.

  19. Evaluation of the new radiation belt AE9/AP9/SPM model for a cislunar mission

    NASA Astrophysics Data System (ADS)

    Badavi, Francis F.; Walker, Steven A.; Santos Koos, Lindsey M.

    2014-09-01

    Space mission planners continue to experience challenges associated with human space flight. Concerned with the omnipresence of harmful ionizing radiation in space, at the mission design stage, mission planners must evaluate the amount of exposure the crew of a spacecraft is subjected to during the transit trajectory from low Earth orbit (LEO) to geosynchronous orbit (GEO) and beyond (free space). The Earth's geomagnetic field is located within the domain of LEO-GEO and, depending on latitude, extends out some 40,000-60,000 km. This field contains the Van Allen trapped electrons, protons, and low-energy plasmas, such as the nuclei of hydrogen, helium, oxygen, and to a lesser degree other atoms. In addition, there exist the geomagnetically attenuated energetic galactic cosmic rays (GCR). These particles are potentially harmful to improperly shielded crew members and onboard subsystems. Mitigation strategies to limit the exposure due to free space GCR and sporadic solar energetic particles (SEP) such as flare and coronal mass ejection (CME) must also be exercised beyond the trapped field. Presented in this work is the exposure analysis for a multi-vehicle mission planned for the epoch of February 2020 from LEO to the Earth-moon Lagrange-point two (L2), located approximately 63,000 km beyond the orbit of the Earth-moon binary system. Space operation at L2 provides a gravitationally stable orbit for a vehicle and partially eliminates the need for periodic thrust-vectoring to maintain orbital stability. In the cislunar (Earth-moon) space of L2, the mission trajectory and timeline in this work call for a cargo vehicle to rendezvous with a crew vehicle. This is followed by 15 days of space activities at L2 while the cargo and crew vehicles are docked after which the crew returns to Earth. The mission epoch of 2020 is specifically chosen as it is anticipated that the next solar minimum (i.e. end of cycle 24) in the Sun's approximate 11 years cycle will take place around this time. From a mission planning point of view, this date is ideal as the predictable GCR exposure will be at a maximum, while the sporadic SEP will be at a minimum. In addition, it is anticipated that by 2020 a vehicle capable of launching a crew of four will be operationally ready. During the LEO-GEO transit, the crew and cargo vehicles will encounter exposure from trapped particles and attenuated GCR, followed by free space exposure due to GCR and SEP during solar active times. Within the trapped field, a challenge arises from properly calculating the amount of exposure acquired. Within this field, in the absence of SEP (i.e. solar quiet times), the vehicles will have to transit through an inner proton belt, an inner and outer electron belts, and an attenuated GCR field. There exist a number of models to define the intensities of the trapped particles during the quiet and active SEP. Among the more established trapped models are the historic and popular electron/proton AE8/AP8 model dating back to the 1980s, the historic and less popular electron/proton CRRES model dating back to 1990s, and the recently released electron/proton/space plasma AE9/AP9/SPM model. The AE9/AP9/SPM model is a major improvement over the older AE8/AP8 and CRRES models. This model is derived from numerous measurements acquired over four solar cycles dating back to the 1970s, roughly representing 40 years of data collection. In contrast, the older AE8/AP8 and CRRES models were limited to only a few months of measurements taken during the prior solar minima and maxima. In this work, within the trapped field, along the design trajectory of the crew vehicle, the AE9/AP9/SPM model is evaluated against the older AE8/AP8 model during solar quiet times. The analysis is then extended to the GCR dominated en-route, cislunar L2 space and return trajectories in order to provide cumulative exposure estimates to the crew vehicle for the duration of the entire mission.

  20. Assessing the depth of hypnosis of xenon anaesthesia with the EEG.

    PubMed

    Stuttmann, Ralph; Schultz, Arthur; Kneif, Thomas; Krauss, Terence; Schultz, Barbara

    2010-04-01

    Xenon was approved as an inhaled anaesthetic in Germany in 2005 and in other countries of the European Union in 2007. Owing to its low blood/gas partition coefficient, xenons effects on the central nervous system show a fast onset and offset and, even after long xenon anaesthetics, the wake-up times are very short. The aim of this study was to examine which electroencephalogram (EEG) stages are reached during xenon application and whether these stages can be identified by an automatic EEG classification. Therefore, EEG recordings were performed during xenon anaesthetics (EEG monitor: Narcotrend®). A total of 300 EEG epochs were assessed visually with regard to the EEG stages. These epochs were also classified automatically by the EEG monitor Narcotrend® using multivariate algorithms. There was a high correlation between visual and automatic classification (Spearman's rank correlation coefficient r=0.957, prediction probability Pk=0.949). Furthermore, it was observed that very deep stages of hypnosis were reached which are characterised by EEG activity in the low frequency range (delta waves). The burst suppression pattern was not seen. In deep hypnosis, in contrast to the xenon EEG, the propofol EEG was characterised by a marked superimposed higher frequency activity. To ensure an optimised dosage for the single patient, anaesthetic machines for xenon should be combined with EEG monitoring. To date, only a few anaesthetic machines for xenon are available. Because of the high price of xenon, new and further developments of machines focus on optimizing xenon consumption.

  1. Comparison of a single-channel EEG sleep study to polysomnography

    PubMed Central

    Lucey, Brendan P.; McLeland, Jennifer S.; Toedebusch, Cristina D.; Boyd, Jill; Morris, John C.; Landsness, Eric C.; Yamada, Kelvin; Holtzman, David M.

    2016-01-01

    Summary An accurate home sleep study to assess electroencephalography (EEG)-based sleep stages and EEG power would be advantageous for both clinical and research purposes, such as for longitudinal studies measuring changes in sleep stages over time. The purpose of this study was to compare sleep scoring of a single-channel EEG recorded simultaneously on the forehead against attended polysomnography. Participants were recruited from both a clinical sleep center and a longitudinal research study investigating cognitively-normal aging and Alzheimer's disease. Analysis for overall epoch-by-epoch agreement found strong and substantial agreement between the single-channel EEG compared to polysomnography (kappa=0.67). Slow wave activity in the frontal regions was also similar when comparing the single-channel EEG device to polysomnography. As expected, stage N1 showed poor agreement (sensitivity 0.2) due to lack of occipital electrodes. Other sleep parameters such as sleep latency and REM onset latency had decreased agreement. Participants with disrupted sleep consolidation, such as from obstructive sleep apnea, also had poor agreement. We suspect that disagreement in sleep parameters between the single-channel EEG and polysomnography is partially due to altered waveform morphology and/or poorer signal quality in the single-channel derivation. Our results show that single-channel EEG provides comparable results to polysomnography in assessing REM, combined stages N2 and N3 sleep, and several other parameters including frontal slow wave activity. The data establish that single-channel EEG can be a useful research tool. PMID:27252090

  2. 40 CFR Table 3 to Subpart Jjjjjj... - Operating Limits for Boilers With Emission Limits

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... as defined in § 63.11237. 4. Dry sorbent or activated carbon injection control Maintain the 30-day rolling average sorbent or activated carbon injection rate at or above the minimum sorbent injection rate or minimum activated carbon injection rate as defined in § 63.11237. When your boiler operates at...

  3. The orbit of asteroid (99942) Apophis as determined from optical and radar observations

    NASA Astrophysics Data System (ADS)

    Vinogradova, T. A.; Kochetova, O. M.; Chernetenko, Yu. A.; Shor, V. A.; Yagudina, E. I.

    2008-08-01

    The results of improving the orbit accuracy for the asteroid Apophis and the circumstances of its approach to Earth in 2029 are described. Gravitational perturbations from all of the major planets and Pluto, Ceres, Pallas, and Vesta are taken into account in the equations of motion of the asteroid. Relativistic perturbations from the Sun and perturbations due to the oblateness of the Sun and Earth and due to the light pressure are also included in the model. Perturbations from the Earth and Moon are considered separately. The coordinates of the perturbing bodies are calculated using DE405. The phase correction and the gravitational deflection of light are taken into account. The numerical integration of the equations of motion and equations in variations is performed by the 15th-order Everhart method. The error of the numerical integration over the 2005 2029 interval, estimated using forward and backward computations, is not more than 3 × 10-11 AU. Improved coordinates and velocities at epoch JD2454200.5 (April 10, 2007) were obtained applying the weighted leastsquares fit. For the period from March 15, 2004, to August 16, 2006, 989 optical and 7 radar observations were used. The resulting system represents the optical observations with an error of 0.37 (66 conditional equations were rejected). The residuals of the radar observations are an order, or more, smaller than their errors. The system of Apophis’ elements and the estimates of their precision obtained in this study are in perfect agreement with the results published by other authors. The minimum Apophis-Earth distance is about 38 200 km on April 13, 2029. This estimate agrees to within 20 km with those calculated based on other published systems of elements. The effect of some model components on the minimum distance is estimated.

  4. Continuously Deformation Monitoring of Subway Tunnel Based on Terrestrial Point Clouds

    NASA Astrophysics Data System (ADS)

    Kang, Z.; Tuo, L.; Zlatanova, S.

    2012-07-01

    The deformation monitoring of subway tunnel is of extraordinary necessity. Therefore, a method for deformation monitoring based on terrestrial point clouds is proposed in this paper. First, the traditional adjacent stations registration is replaced by sectioncontrolled registration, so that the common control points can be used by each station and thus the error accumulation avoided within a section. Afterwards, the central axis of the subway tunnel is determined through RANSAC (Random Sample Consensus) algorithm and curve fitting. Although with very high resolution, laser points are still discrete and thus the vertical section is computed via the quadric fitting of the vicinity of interest, instead of the fitting of the whole model of a subway tunnel, which is determined by the intersection line rotated about the central axis of tunnel within a vertical plane. The extraction of the vertical section is then optimized using RANSAC for the purpose of filtering out noises. Based on the extracted vertical sections, the volume of tunnel deformation is estimated by the comparison between vertical sections extracted at the same position from different epochs of point clouds. Furthermore, the continuously extracted vertical sections are deployed to evaluate the convergent tendency of the tunnel. The proposed algorithms are verified using real datasets in terms of accuracy and computation efficiency. The experimental result of fitting accuracy analysis shows the maximum deviation between interpolated point and real point is 1.5 mm, and the minimum one is 0.1 mm; the convergent tendency of the tunnel was detected by the comparison of adjacent fitting radius. The maximum error is 6 mm, while the minimum one is 1 mm. The computation cost of vertical section abstraction is within 3 seconds/section, which proves high efficiency..

  5. A hot Jupiter around the very active weak-line T Tauri star TAP 26

    NASA Astrophysics Data System (ADS)

    Yu, L.; Donati, J.-F.; Hébrard, E. M.; Moutou, C.; Malo, L.; Grankin, K.; Hussain, G.; Collier Cameron, A.; Vidotto, A. A.; Baruteau, C.; Alencar, S. H. P.; Bouvier, J.; Petit, P.; Takami, M.; Herczeg, G.; Gregory, S. G.; Jardine, M.; Morin, J.; Ménard, F.; Matysse Collaboration

    2017-05-01

    We report the results of an extended spectropolarimetric and photometric monitoring of the weak-line T Tauri star TAP 26, carried out within the Magnetic Topologies of Young Stars and the Survival of close-in massive Exoplanets (MaTYSSE) programme with the Echelle SpectroPolarimetric Device for the Observation of Stars (ESPaDOnS) spectropolarimeter at the 3.6-m Canada-France-Hawaii Telescope. Applying Zeeman-Doppler Imaging (ZDI) to our observations, concentrating in 2015 November and 2016 January and spanning 72 d in total, 16 d in 2015 November and 13 d in 2016 January, we reconstruct surface brightness and magnetic field maps for both epochs and demonstrate that both distributions exhibit temporal evolution not explained by differential rotation alone. We report the detection of a hot Jupiter (hJ) around TAP 26 using three different methods, two using ZDI and one Gaussian-process regression (GPR), with a false-alarm probability smaller than 6 × 10-4. However, as a result of the aliasing related to the observing window, the orbital period cannot be uniquely determined; the orbital period with highest likelihood is 10.79 ± 0.14 d followed by 8.99 ± 0.09 d. Assuming the most likely period, and that the planet orbits in the stellar equatorial plane, we obtain that the planet has a minimum mass Msin I of 1.66 ± 0.31 MJup and orbits at 0.0968 ± 0.0032 au from its host star. This new detection suggests that disc type II migration is efficient at generating newborn hJs, and that hJs may be more frequent around young T Tauri stars than around mature stars (or that the MaTYSSE sample is biased towards hJ-hosting stars).

  6. Interpretation of a Variable Reflection Nebula Associated with HBC 340 and HBC 341 in NGC 1333

    NASA Astrophysics Data System (ADS)

    Dahm, S. E.; Hillenbrand, L. A.

    2017-11-01

    We present multi-epoch, R-band imaging obtained from the Palomar Transient Factory of a small, fan-shaped reflection nebula in NGC 1333 that experiences prominent brightness fluctuations. Photometry of HBC 340 (K7e) and HBC 341 (M5e), a visual pair of late-type, young stellar objects lying near the apex of the nebula, demonstrates that while both are variable, the former has brightened by more than two magnitudes following a deep local minimum in 2014 September. Keck high-dispersion (R ˜ 45,000-66,000), optical spectroscopy of HBC 340 suggests that the protostar is a spectroscopic binary (HBC 340Aa + HBC 340Ab). Both HBC 340 and HBC 341 exhibit strong Hα and forbidden line emission, consistent with accretion and outflow. We conclude that the brightness fluctuations in the reflection nebula represent light echos produced by varying incident radiation emanating from HBC 340. The short-term variability observed in the protostar is attributed to irregular accretion activity, while correlated, dipping behavior on a several hundred day timescale may be due to eclipse-like events caused by orbiting circumstellar material. Archival Hubble Space Telescope imaging of the region reveals a second, faint (F814W ˜ 20.3 mag) companion to HBC 340 that lies 1.″02 (˜235 au) east of the protostar. If associated, this probable substellar mass object (20-50 Jupiter masses), HBC 340B, is likely unrelated to the observed brightness variations. The sustained brightening of HBC 340 since late 2014 can be explained by an EXor-like outburst, the recovery from a long duration eclipse event caused by obscuring circumstellar dust, or by the gradual removal of extincting material from along the line of sight. Our analysis here favors one of the extinction scenarios.

  7. Methodological Caveats in the Detection of Coordinated Replay between Place Cells and Grid Cells.

    PubMed

    Trimper, John B; Trettel, Sean G; Hwaun, Ernie; Colgin, Laura Lee

    2017-01-01

    At rest, hippocampal "place cells," neurons with receptive fields corresponding to specific spatial locations, reactivate in a manner that reflects recently traveled trajectories. These "replay" events have been proposed as a mechanism underlying memory consolidation, or the transfer of a memory representation from the hippocampus to neocortical regions associated with the original sensory experience. Accordingly, it has been hypothesized that hippocampal replay of a particular experience should be accompanied by simultaneous reactivation of corresponding representations in the neocortex and in the entorhinal cortex, the primary interface between the hippocampus and the neocortex. Recent studies have reported that coordinated replay may occur between hippocampal place cells and medial entorhinal cortex grid cells, cells with multiple spatial receptive fields. Assessing replay in grid cells is problematic, however, as the cells exhibit regularly spaced spatial receptive fields in all environments and, therefore, coordinated replay between place cells and grid cells may be detected by chance. In the present report, we adapted analytical approaches utilized in recent studies of grid cell and place cell replay to determine the extent to which coordinated replay is spuriously detected between grid cells and place cells recorded from separate rats. For a subset of the employed analytical methods, coordinated replay was detected spuriously in a significant proportion of cases in which place cell replay events were randomly matched with grid cell firing epochs of equal duration. More rigorous replay evaluation procedures and minimum spike count requirements greatly reduced the amount of spurious findings. These results provide insights into aspects of place cell and grid cell activity during rest that contribute to false detection of coordinated replay. The results further emphasize the need for careful controls and rigorous methods when testing the hypothesis that place cells and grid cells exhibit coordinated replay.

  8. A THEMIS Survey of Flux Ropes and Traveling Compression Regions: Location of the Near-Earth Reconnection Site During Solar Minimum

    NASA Technical Reports Server (NTRS)

    Imber, S. M.; Slavin, J. A.; Auster, H. U.; Angelopoulos, V.

    2011-01-01

    A statistical study of flux ropes and traveling compression regions (TCRs) during the Time History of Events and Macroscale Interactions during Substorms (THEMIS) second tail season has been performed. A combined total of 135 flux ropes and TCRs in the range GSM X approx -14 to -31 R(sub E) were identified, many of these occurring in series of two or more events separated by a few tens of seconds. Those occurring within 10 min of each other were combined into aggregated reconnection events. For the purposes of this survey, these are most likely the products of reconnect ion occurring simultaneously at multiple, closely spaced x-lines as opposed to statistically independent episodes of reconnection. The 135 flux ropes and TCRs were grouped into 87 reconnection events; of these, 28 were moving tailward and 59 were moving Earthward. The average location of the near-Earth x-line determined from statistical analysis of these reconnection events is (X(sub GSM), Y*(sub GSM)) = (-30R(sub E), 5R(sub E)), where Y* includes a correction for the solar aberration angle. A strong east-west asymmetry is present in the tailward events, with >80% being observed at GSM Y* > O. Our results indicate that the Earthward flows are similarly asymmetric in the midtail region, becoming more symmetric inside - 18 R(sub E). Superposed epoch analyses indicate that the occurrence of reconnection closer to the Earth, i.e., X > -20 R(sub E), is associated with elevated solar wind velocity and enhanced negative interplanetary magnetic field B(sub z). Reconnection events taking place closer to the Earth are also far more effective in producing geomagnetic activity, judged by the AL index, than reconnection initiated beyond X approx -25 R(sub E).

  9. 42 CFR 84.196 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Chemical Cartridge Respirators § 84.196 Harnesses; installation and construction; minimum...

  10. Evolution of galaxy structure using visual morphologies in CANDELS and Hydro-ART simulations

    NASA Astrophysics Data System (ADS)

    Mozena, Mark W.

    2013-08-01

    The general properties, morphologies, and classes of galaxies in the local Universe are well studied. Most local galaxies are morphologically members of the Hubble sequence and can be crudely separated into elliptical red quiescent galaxies or disky blue star-forming galaxies. This Hubble sequence of relaxed structures has been shown to dominate galaxy populations out to a redshift of z~1. The description of galaxies at earlier times is not well known nor is it understood how and at what epoch the Hubble sequence formed. Of particular interest is the structure of galaxies at z~2. This epoch was an active time for galaxy growth and was the peak epoch for star formation rate, active galactic nuclei activity, and mergers between galaxies. With the installation of the near-infrared Wide Field Camera 3 (WFC3) on the Hubble Space Telescope in 2009, large area photometric surveys of galaxies were able to be performed for the first time at moderate redshifts (z~2) in wavebands that effectively trace the older stellar populations and stellar mass of the galaxies rather than the clumpy star-forming regions. Using WFC3 HST images, an in-depth morphology classification system was developed to probe the galaxy populations at higher redshifts (focusing on z~2). These visual classifications were used with other galaxy parameters (stellar mass, color, star formation rate, radius, Sersic profiles, etc) to identify and quantify the moderate redshift galaxy populations and study how these populations changed with time to form the relaxed Hubble sequence Universe we observe today. Additionally, these same tools that were used to probe galaxy populations at z~2 in the observed Universe were also used on simulated galaxy images produced from state-of-the-art cosmological simulations. These Hydro-ART simulations build artificial galaxies that are compared to observations so as to shed light on the relevant mechanisms in galaxy evolution. By classifying and comparing the populations present in the simulations with our observations, we are able to probe the model's ability to create realistic galaxy populations. The first chapter of this thesis focuses on visually classifying and studying galaxy populations at z~2 and how they change with redshift for a given mass. The second chapter focuses on applying our techniques to Hydro-ART simulations at z~2 and comparing these mock 'observed' simulations with our real WFC3 HST observations. Both of these chapters closely resemble manuscripts in the process of being submitted for independent publication.

  11. Tracing Evolution of Starbursts and AGNs using Ultra-deep Radio and mm/smm Surveys

    NASA Astrophysics Data System (ADS)

    Yun, Min S.; Gim, Hansung; Morrison, Glenn; Hales, Christopher A.; Momjian, Emmanuel; Owen, Frazer; Kellermann, Ken; Aretxaga, Itziar; Giavalisco, Mauro; Hughes, David; Lowenthal, James; Miller, Neal; Kawabe, Ryohei; Kohno, Kotaro

    2015-08-01

    There is growing evidence supporting a rapid build up of metals among massive galaxies during their rapid growth via an intense starburst in the early epochs. These star formation activities may be largely obscured in the UV and optical light, as in the local universe. If the growth of supermassive blackholes occurs at or nearly the same time, the accompanying AGN activity may also be heavily obscured. Ultra-deep surveys in the radio and far-infrared can offer extinction-free view of these systems, and the advent of new facilities such as the Jansky VLA, ALMA, and LMT now allows us to probe directly the population of starburst galaxies that are responsible for the bulk of the stellar mass build-up during the epoch of galaxy growth (SFR > 10-100 M⊙/yr at z≈2 or earlier). We will present our analysis of the properties of the micro-Jansky radio sources identified by new Jansky VLA surveys of the GOODS and COSMOS fields using the rich archival data already available (Herschel, Spitzer, Chandra, ALMA, LMT, etc.). Specifically, we find evidence for two populations of microJy radio sources with distinct spectral index distribution. We explore whether this reflects differences in the underlying powering mechanisms by examining their radio-FIR correlation and X-ray properties. We also find the previously reported apparent systematic change in the "q-value" with increasing redshift, and we examine the reality of this trend in some detail. Finally, we will also examine the spatial extent of activities for a subset of the sample where high angular resolution (better than 1") information is available.

  12. Van Allen Probe Observations of Chorus Wave Activity, Source and Seed electrons, and the Radiation Belt Response During ICME and CIR Storms

    NASA Astrophysics Data System (ADS)

    Bingham, S.; Mouikis, C.; Kistler, L. M.; Farrugia, C. J.; Paulson, K. W.; Huang, C. L.; Boyd, A. J.; Spence, H. E.; Kletzing, C.

    2017-12-01

    Whistler mode chorus waves are electromagnetic waves that have been shown to be a major contributor to enhancements in the outer radiation belt during geomagnetic storms. The temperature anisotropy of source electrons (10s of keV) provides the free energy for chorus waves, which can accelerate sub-relativistic seed electrons (100s of keV) to relativistic energies. This study uses Van Allen Probe observations to examine the excitation and plasma conditions associated with chorus wave observations, the development of the seed population, and the outer radiation belt response in the inner magnetosphere, for 25 ICME and 35 CIR storms. Plasma data from the Helium Oxygen Proton Electron (HOPE) instrument and magnetic field measurements from the Electric and Magnetic Field Instrument Suite and Integrated Science (EMFISIS) are used to identify chorus wave activity and to model a linear theory based proxy for chorus wave growth. A superposed epoch analysis shows a peak of chorus wave power on the dawnside during the storm main phase that spreads towards noon during the storm recovery phase. According to the linear theory results, this wave activity is driven by the enhanced convection driving plasma sheet electrons across the dayside. Both ICME and CIR storms show comparable levels of wave growth. Plasma data from the Magnetic Electron Ion Spectrometer (MagEIS) and the Relativistic Electron Proton Telescope (REPT) are used to observe the seed and relativistic electrons. A superposed epoch analysis of seed and relativistic electrons vs. L shows radiation belt enhancements with much greater frequency in the ICME storms, coinciding with a much stronger and earlier seed electron enhancement in the ICME storms.

  13. VizieR Online Data Catalog: NIR proper motion catalogue from UKIDSS-LAS (Smith+, 2014)

    NASA Astrophysics Data System (ADS)

    Smith, L.; Lucas, P. W.; Burningham, B.; Jones, H. R. A.; Smart, R. L.; Andrei, A. H.; Catalan, S.; Pinfield, D. J.

    2015-07-01

    We constructed two epoch catalogues for each pointing by matching sources within the pairs of multiframes using the Starlink Tables Infrastructure Library Tool Set (STILTS; Taylor 2006, ASP conf. Ser. 351, 666). We required pairs of sources to be uniquely paired to their closest match within 6-arcsec, and we required the J band magnitudes for the two epochs to agree within 0.5mag, to minimize mismatches. (1 data file).

  14. SPECTROPOLARIMETRY OF SUPERLUMINOUS SUPERNOVAE: INSIGHT INTO THEIR GEOMETRY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Inserra, C.; Bulla, M.; Sim, S. A.

    2016-11-01

    We present the first spectropolarimetric observations of a hydrogen-free superluminous supernova (SLSN) at z = 0.1136, namely SN 2015bn. The transient shows significant polarization at both of the observed epochs: one 24 days before maximum light in the rest-frame, and the other at 27 days after peak luminosity. Analysis of the Q – U plane suggests the presence of a dominant axis and no physical departure from the main axis at either epoch. The polarization spectrum along the dominant axis is characterized by a strong wavelength dependence and an increase in the signal from the first to the second epoch.more » We use a Monte Carlo code to demonstrate that these properties are consistent with a simple toy model that adopts an axisymmetric ellipsoidal configuration for the ejecta. We find that the wavelength dependence of the polarization is possibly due to a strong wavelength dependence in the line opacity, while the higher level of polarization at the second epoch is a consequence of the increase in the asphericity of the inner layers of the ejecta or the fact that the photosphere recedes into less spherical layers. The geometry of the SLSN is similar to that of stripped-envelope core-collapse SNe connected to GRB, while the overall evolution of the ejecta shape could be consistent with a central engine.« less

  15. Epoch-based likelihood models reveal no evidence for accelerated evolution of viviparity in squamate reptiles in response to cenozoic climate change.

    PubMed

    King, Benedict; Lee, Michael S Y

    2015-09-01

    A broad scale analysis of the evolution of viviparity across nearly 4,000 species of squamates revealed that origins increase in frequency toward the present, raising the question of whether rates of change have accelerated. We here use simulations to show that the increased frequency is within the range expected given that the number of squamate lineages also increases with time. Novel, epoch-based methods implemented in BEAST (which allow rates of discrete character evolution to vary across time-slices) also give congruent results, with recent epochs having very similar rates to older epochs. Thus, contrary to expectations, there was no accelerated burst of origins of viviparity in response to global cooling during the Cenozoic or glacial cycles during the Plio-Pleistocene. However, if one accepts the conventional view that viviparity is more likely to evolve than to be lost, and also the evidence here that viviparity has evolved with similar regularity throughout the last 200 Ma, then the absence of large, ancient clades of viviparous squamates (analogs to therian mammals) requires explanation. Viviparous squamate lineages might be more prone to extinction than are oviparous lineages, due to their prevalance at high elevations and latitudes and thus greater susceptibility to climate fluctuations. If so, the directional bias in character evolution would be offset by the bias in extinction rates. © 2015 Wiley Periodicals, Inc.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bag, Satadru; Sahni, Varun; Viznyuk, Alexander

    We obtain a closed system of equations for scalar perturbations in a multi-component braneworld. Our braneworld possesses a phantom-like equation of state at late times, w {sub eff} < −1, but no big-rip future singularity. In addition to matter and radiation, the braneworld possesses a new effective degree of freedom—the 'Weyl fluid' or 'dark radiation'. Setting initial conditions on super-Hubble spatial scales at the epoch of radiation domination, we evolve perturbations of radiation, pressureless matter and the Weyl fluid until the present epoch. We observe a gradual decrease in the amplitude of the Weyl-fluid perturbations after Hubble-radius crossing, which resultsmore » in a negligible effect of the Weyl fluid on the evolution of matter perturbations on spatial scales relevant for structure formation. Consequently, the quasi-static approximation of Koyama and Maartens provides a good fit to the exact results during the matter-dominated epoch. We find that the late-time growth of density perturbations on the brane proceeds at a faster rate than in ΛCDM. Additionally, the gravitational potentials Φ and Ψ evolve differently on the brane than in ΛCDM, for which Φ = Ψ. On the brane, by contrast, the ratio Φ/Ψ exceeds unity during the late matter-dominated epoch ( z ∼< 50). These features emerge as smoking gun tests of phantom brane cosmology and allow predictions of this scenario to be tested against observations of galaxy clustering and large-scale structure.« less

  17. Emulating Simulations of Cosmic Dawn for 21 cm Power Spectrum Constraints on Cosmology, Reionization, and X-Ray Heating

    NASA Astrophysics Data System (ADS)

    Kern, Nicholas S.; Liu, Adrian; Parsons, Aaron R.; Mesinger, Andrei; Greig, Bradley

    2017-10-01

    Current and upcoming radio interferometric experiments are aiming to make a statistical characterization of the high-redshift 21 cm fluctuation signal spanning the hydrogen reionization and X-ray heating epochs of the universe. However, connecting 21 cm statistics to the underlying physical parameters is complicated by the theoretical challenge of modeling the relevant physics at computational speeds quick enough to enable exploration of the high-dimensional and weakly constrained parameter space. In this work, we use machine learning algorithms to build a fast emulator that can accurately mimic an expensive simulation of the 21 cm signal across a wide parameter space. We embed our emulator within a Markov Chain Monte Carlo framework in order to perform Bayesian parameter constraints over a large number of model parameters, including those that govern the Epoch of Reionization, the Epoch of X-ray Heating, and cosmology. As a worked example, we use our emulator to present an updated parameter constraint forecast for the Hydrogen Epoch of Reionization Array experiment, showing that its characterization of a fiducial 21 cm power spectrum will considerably narrow the allowed parameter space of reionization and heating parameters, and could help strengthen Planck's constraints on {σ }8. We provide both our generalized emulator code and its implementation specifically for 21 cm parameter constraints as publicly available software.

  18. How unprecedented a solar minimum was it?

    PubMed

    Russell, C T; Jian, L K; Luhmann, J G

    2013-05-01

    The end of the last solar cycle was at least 3 years late, and to date, the new solar cycle has seen mainly weaker activity since the onset of the rising phase toward the new solar maximum. The newspapers now even report when auroras are seen in Norway. This paper is an update of our review paper written during the deepest part of the last solar minimum [1]. We update the records of solar activity and its consequent effects on the interplanetary fields and solar wind density. The arrival of solar minimum allows us to use two techniques that predict sunspot maximum from readings obtained at solar minimum. It is clear that the Sun is still behaving strangely compared to the last few solar minima even though we are well beyond the minimum phase of the cycle 23-24 transition.

  19. 42 CFR 84.173 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE... construction; minimum requirements. (a) Each respirator shall, where necessary, be equipped with a suitable...

  20. 42 CFR 84.133 - Harnesses; installation and construction; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Harnesses; installation and construction; minimum... SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Supplied-Air Respirators § 84.133 Harnesses; installation and construction; minimum requirements...

  1. A subharmonic dynamical bifurcation during in vitro epileptiform activity

    NASA Astrophysics Data System (ADS)

    Perez Velazquez, Jose L.; Khosravani, Houman

    2004-06-01

    Epileptic seizures are considered to result from a sudden change in the synchronization of firing neurons in brain neural networks. We have used an in vitro model of status epilepticus (SE) to characterize dynamical regimes underlying the observed seizure-like activity. Time intervals between spikes or bursts were used as the variable to construct first-return interpeak or interburst interval plots, for studying neuronal population activity during the transition to seizure, as well as within seizures. Return maps constructed for a brief epoch before seizures were used for approximating the local system dynamics during that time window. Analysis of the first-return maps suggests that intermittency is a dynamical regime underlying the observed epileptic activity. This type of analysis may be useful for understanding the collective dynamics of neuronal populations in the normal and pathological brain.

  2. [The business game as a form of organization of competent approach in teaching of history of medicine].

    PubMed

    Konopleva, E L; Ostapenko, V M

    2015-01-01

    The article considers issue of implementation of competent approach in teaching of course of history of medicine in medical universities. The such methods of active training as imitation role business games are proposed as a mean of developing common cultural and professional competences offuture medical personnel. The business games promote development of motivation basis or education and require activities related to practical implementation of acquired knowledge and skills (analysis of historical event, work with map, reading of historical documents, participation in scientific discussion, etc.). As a result, students acquire sufficiently large notion concerning world of medicine, relationship of historical epochs and occurrences and unity of medical systems.

  3. Predicting present-day rates of glacial isostatic adjustment using a smoothed GPS velocity field for the reconciliation of NAD83 reference frames in Canada

    NASA Astrophysics Data System (ADS)

    Craymer, M. R.; Henton, J. A.; Piraszewski, M.

    2008-12-01

    Glacial isostatic adjustment following the last glacial period is the dominant source of crustal deformation in Canada east of the Rocky Mountains. The present-day vertical component of motion associated with this process may exceed 1 cm/y and is being directly measured with the Global Positioning System (GPS). A consequence of this steady deformation is that high accuracy coordinates at one epoch may not be compatible with those at another epoch. For example, modern precise point positioning (PPP) methods provide coordinates at the epoch of observation while NAD83, the officially adopted reference frame in Canada and the U.S., is expressed at some past reference epoch. The PPP positions are therefore incompatible with coordinates in such a realization of the reference frame and need to be propagated back to the frame's reference epoch. Moreover, the realizations of NAD83 adopted by the provincial geodetic agencies in Canada are referenced to different coordinate epochs; either 1997.0 or 2002.0. Proper comparison of coordinates between provinces therefore requires propagating them from one reference epoch to another. In an effort to reconcile PPP results and different realizations of NAD83, we empirically represent crustal deformation throughout Canada using a velocity field based solely on high accuracy continuous and episodic GPS observations. The continuous observations from 2001 to 2007 were obtained from nearly 100 permanent GPS stations, predominately operated by Natural Resources Canada (NRCan) and provincial geodetic agencies. Many of these sites are part of the International GNSS Service (IGS) global network. Episodic observations from 1994 to 2006 were obtained from repeated occupations of the Canadian Base Network (CBN), which consists of approximately 160 stable pillar-type monuments across the entire country. The CBN enables a much denser spatial sampling of crustal motions although coverage in the far north is still rather sparse. NRCan solutions of the continuous GPS data were combined with those from other agencies as part of the North American Reference Frame (NAREF) effort to improve the reliability of the results. This NAREF solution has then been combined with our CBN results to obtain a denser velocity sampling for fitting different types of surfaces in a first attempt to determine a continuous GPS velocity field for the entire country. Expressing this velocity field as a grid enables users to interpolate to any location in Canada, allowing for the propagation of coordinates to any desired reference epoch. We examine the accuracy and limitations of this GPS velocity field by comparing it to other published GPS velocity solutions (which are all based on less data) as well as to GIA models, including versions of ICE-3G, ICE-5G and the recent Stable North America Reference Frame (SNARF) model. Of course, the accuracy of the GPS velocity field depends directly on the density of the GPS coverage. Consequently, the GPS velocity field is unable to fully represent the actual GIA motion in the far north and tends to smooth out the signal due to the spatially sparse coverage. On the other hand, the model performs quite well in the southern parts of the country where there is a much greater spatial density of GPS measurements.

  4. Sunspot Observations During the Maunder Minimum from the Correspondence of John Flamsteed

    NASA Astrophysics Data System (ADS)

    Carrasco, V. M. S.; Vaquero, J. M.

    2016-11-01

    We compile and analyze the sunspot observations made by John Flamsteed for the period 1672 - 1703, which corresponds to the second part of the Maunder Minimum. They appear in the correspondence of the famous astronomer. We include in an appendix the original texts of the sunspot records kept by Flamsteed. We compute an estimate of the level of solar activity using these records, and compare the results with the latest reconstructions of solar activity during the Maunder Minimum, obtaining values characteristic of a grand solar minimum. Finally, we discuss a phenomenon observed and described by Stephen Gray in 1705 that has been interpreted as a white-light flare.

  5. Estimation of metabolic energy expenditure from core temperature using a human thermoregulatory model.

    PubMed

    Welles, Alexander P; Buller, Mark J; Looney, David P; Rumpler, William V; Gribok, Andrei V; Hoyt, Reed W

    2018-02-01

    Human metabolic energy expenditure is critical to many scientific disciplines but can only be measured using expensive and/or restrictive equipment. The aim of this work is to determine whether the SCENARIO thermoregulatory model can be adapted to estimate metabolic rate (M) from core body temperature (T C ). To validate this method of M estimation, data were collected from fifteen test volunteers (age = 23 ± 3yr, height = 1.73 ± 0.07m, mass = 68.6 ± 8.7kg, body fat = 16.7 ± 7.3%; mean ± SD) who wore long sleeved nylon jackets and pants (I tot,clo = 1.22, I m = 0.41) during treadmill exercise tasks (32 trials; 7.8 ± 0.5km in 1h; air temp. = 22°C, 50% RH, wind speed = 0.35ms -1 ). Core body temperatures were recorded by ingested thermometer pill and M data were measured via whole room indirect calorimetry. Metabolic rate was estimated for 5min epochs in a two-step process. First, for a given epoch, a range of M values were input to the SCENARIO model and a corresponding range of T C values were output. Second, the output T C range value with the lowest absolute error relative to the observed T C for the given epoch was identified and its corresponding M range input was selected as the estimated M for that epoch. This process was then repeated for each subsequent remaining epoch. Root mean square error (RMSE), mean absolute error (MAE), and bias between observed and estimated M were 186W, 130 ± 174W, and 33 ± 183W, respectively. The RMSE for total energy expenditure by exercise period was 0.30 MJ. These results indicate that the SCENARIO model is useful for estimating M from T C when measurement is otherwise impractical. Published by Elsevier Ltd.

  6. Multi-epoch VLBA Imaging of 20 New TeV Blazars: Apparent Jet Speeds

    NASA Astrophysics Data System (ADS)

    Piner, B. Glenn; Edwards, Philip G.

    2018-01-01

    We present 88 multi-epoch Very Long Baseline Array (VLBA) images (most at an observing frequency of 8 GHz) of 20 TeV blazars, all of the high-frequency-peaked BL Lac (HBL) class, that have not been previously studied at multiple epochs on the parsec scale. From these 20 sources, we analyze the apparent speeds of 43 jet components that are all detected at four or more epochs. As has been found for other TeV HBLs, the apparent speeds of these components are relatively slow. About two-thirds of the components have an apparent speed that is consistent (within 2σ) with no motion, and some of these components may be stationary patterns whose apparent speed does not relate to the underlying bulk flow speed. In addition, a superluminal tail to the apparent speed distribution of the TeV HBLs is detected for the first time, with eight components in seven sources having a 2σ lower limit on the apparent speed exceeding 1c. We combine the data from these 20 sources with an additional 18 sources from the literature to analyze the complete apparent speed distribution of all 38 TeV HBLs that have been studied with very long baseline interferometry at multiple epochs. The highest 2σ apparent speed lower limit considering all sources is 3.6c. This suggests that bulk Lorentz factors of up to about 4, but probably not much higher, exist in the parsec-scale radio-emitting regions of these sources, consistent with estimates obtained in the radio by other means such as brightness temperatures. This can be reconciled with the high Lorentz factors estimated from the high-energy data if the jet has velocity structures consisting of different emission regions with different Lorentz factors. In particular, we analyze the current apparent speed data for the TeV HBLs in the context of a model with a fast central spine and a slower outer layer.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pinnix, Chelsea C.; Dabaja, Bouthaina, E-mail: bdabaja@mdanderson.org; Ahmed, Mohamed Amin

    Purpose: Excellent outcomes obtained after infusional dose-adjusted etoposide, doxorubicin, cyclophosphamide, vincristine, prednisone, and rituximab (R-EPOCH) alone have led some to question the role of consolidative radiation therapy (RT) in the treatment of primary mediastinal B cell lymphoma (PMBL). We reviewed the outcomes in patients treated with 1 of 3 rituximab-containing regimens (cyclophosphamide, doxorubicin, vincristine, prednisone [R-CHOP]; hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone [R-HCVAD], or R-EPOCH) with or without RT. We also evaluated the ability of positron emission tomography–computed tomography (PET-CT) to identify patients at risk of relapse. Methods and Materials: We retrospectively identified 97 patients with diagnoses of stage I/IImore » PMBCL treated at our institution between 2001 and 2013. The clinical characteristics, treatment outcomes, and toxicity were assessed. We analyzed whether postchemotherapy PET-CT could identify patients at risk for progressive disease according to a 5 point scale (5PS) Deauville score assigned. Results: Among 97 patients (median follow-up time, 57 months), the 5-year overall survival rate was 99%. Of patients treated with R-CHOP, 99% received RT; R-HCVAD, 82%; and R-EPOCH, 36%. Of 68 patients with evaluable end-of-chemotherapy PET-CT scans, 62% had a positive scan (avidity above that of the mediastinal blood pool [Deauville 5PS = 3]), but only 9 patients experienced relapse (n=1) or progressive disease (n=8), all with a 5PS of 4 to 5. Of the 25 patients who received R-EPOCH, 4 experienced progression, all with 5PS of 4 to 5; salvage therapy (RT and autologous stem cell transplantation) was successful in all cases. Conclusion: Combined modality immunochemotherapy and RT is well tolerated and effective for treatment of PMBCL. A postchemotherapy 5PS of 4 to 5, rather than 3 to 5, can identify patients at high risk of progression who should be considered for therapy beyond chemotherapy alone after R-EPOCH.« less

  8. CONSTRAINING THE DUST COMA PROPERTIES OF COMET C/SIDING SPRING (2013 A1) AT LARGE HELIOCENTRIC DISTANCES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Jian-Yang; Samarasinha, Nalin H.; Kelley, Michael S. P.

    2014-12-10

    The close encounter of comet C/2013 A1 (Siding Spring) with Mars on 2014 October 19 presented an extremely rare opportunity to obtain the first flyby quality data of the nucleus and inner coma of a dynamically new comet. However, the comet's dust tail potentially posed an impact hazard to those spacecraft orbiting Mars. To characterize the comet at large heliocentric distances, study its long-term evolution, and provide critical inputs to hazard modeling, we imaged C/Siding Spring with the Hubble Space Telescope when the comet was at 4.58, 3.77, and 3.28 AU from the Sun. The dust production rate, parameterized bymore » the quantity Afρ, was 2500, 2100, and 1700 cm (5000 km radius aperture) for the three epochs, respectively. The color of the dust coma is (5.0 ± 0.3)%/100 nm for the first two epochs, and (9.0 ± 0.3)%/100 nm for the last epoch, and reddens with increasing cometocentric distance out to ∼3000 km from the nucleus. The spatial distribution and the temporal evolution of the dust color are most consistent with the existence of icy grains in the coma. Two jet-like dust features appear in the northwest and south-southeast directions projected in the sky plane. Within each epoch of 1-2 hr, no temporal variations were observed for either feature, but the position angle of the south-southeastern feature varied between the three epochs by ∼30°. The dust feature morphology suggests two possible orientations for the rotational pole of the nucleus, (R.A., decl.) = (295° ± 5°, +43° ± 2°) and (190° ± 10°, +50° ± 5°), or their diametrically opposite orientations.« less

  9. A Map of Anticipatory Activity in Mouse Motor Cortex.

    PubMed

    Chen, Tsai-Wen; Li, Nuo; Daie, Kayvon; Svoboda, Karel

    2017-05-17

    Activity in the mouse anterior lateral motor cortex (ALM) instructs directional movements, often seconds before movement initiation. It is unknown whether this preparatory activity is localized to ALM or widely distributed within motor cortex. Here we imaged activity across motor cortex while mice performed a whisker-based object localization task with a delayed, directional licking response. During tactile sensation and the delay epoch, object location was represented in motor cortex areas that are medial and posterior relative to ALM, including vibrissal motor cortex. Preparatory activity appeared first in deep layers of ALM, seconds before the behavioral response, and remained localized to ALM until the behavioral response. Later, widely distributed neurons represented the outcome of the trial. Cortical area was more predictive of neuronal selectivity than laminar location or axonal projection target. Motor cortex therefore represents sensory, motor, and outcome information in a spatially organized manner. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Modeling of Red Giant and AGB Stars Atmospheres: Constraints from VLTI and HST Observations

    NASA Astrophysics Data System (ADS)

    Rau, Gioia

    2018-04-01

    The chemical enrichment of the Universe is considerably affected by the contributions of low-to-intermediate mass stars through the mass-loss provided via their stellar winds. First, we will present our investigation in the near-IR with VLTI/GRAVITY (Wittkowski, Rau, et al., in prep.). Our aim was to verify at different epochs the model-predicted variability of the visibility spectra. We use CODEX model atmospheres, as well as best-fit 3D radiation hydrodynamic simulations (e.g. Freytag et al., 2017), for comparison with the observations. Our preliminary results on R Peg suggest a decreasing contribution by extended CO layers as the star transitions from maximum to minimum phase. Second, we will show a preliminary modeling of UV spectra obtained with HST/GHRS that contain chromospheric emission lines of, e.g., Mg II and Fe II. Via Sobolev with Exact Integration (SEI) modeling, we determined for the two M-giant stars γ Cru and µ Gem the characteristics of their winds (turbulence, acceleration, and opacity), and their average global mass-loss rates (Rau, Carpenter et al., in prep.). Finally, we briefly discuss the impact of instruments on board JWST in progressing this investigation.

  11. Social vision: sustained perceptual enhancement of affective facial cues in social anxiety

    PubMed Central

    McTeague, Lisa M.; Shumen, Joshua R.; Wieser, Matthias J.; Lang, Peter J.; Keil, Andreas

    2010-01-01

    Heightened perception of facial cues is at the core of many theories of social behavior and its disorders. In the present study, we continuously measured electrocortical dynamics in human visual cortex, as evoked by happy, neutral, fearful, and angry faces. Thirty-seven participants endorsing high versus low generalized social anxiety (upper and lower tertiles of 2,104 screened undergraduates) viewed naturalistic faces flickering at 17.5 Hz to evoke steady-state visual evoked potentials (ssVEPs), recorded from 129 scalp electrodes. Electrophysiological data were evaluated in the time-frequency domain after linear source space projection using the minimum norm method. Source estimation indicated an early visual cortical origin of the face-evoked ssVEP, which showed sustained amplitude enhancement for emotional expressions specifically in individuals with pervasive social anxiety. Participants in the low symptom group showed no such sensitivity, and a correlational analysis across the entire sample revealed a strong relationship between self-reported interpersonal anxiety/avoidance and enhanced visual cortical response amplitude for emotional, versus neutral expressions. This pattern was maintained across the 3500 ms viewing epoch, suggesting that temporally sustained, heightened perceptual bias towards affective facial cues is associated with generalized social anxiety. PMID:20832490

  12. Heart rate control in normal and aborted-SIDS infants.

    PubMed

    Pincus, S M; Cummins, T R; Haddad, G G

    1993-03-01

    Approximate entropy (ApEn), a mathematical formula quantifying regularity in data, was applied to heart rate data from normal and aborted-sudden infant death syndrome (SIDS) infants. We distinguished quiet from rapid-eye-movement (REM) sleep via the following three criteria, refining the notion of REM as more "variable": 1) REM sleep has greater overall variability (0.0374 +/- 0.0138 vs. 0.0205 +/- 0.0090 s, P < 0.005); 2) REM sleep is less stationary (StatAv = 0.742 +/- 0.110) than quiet sleep (StatAv = 0.599 +/- 0.159, P < 0.03); 3) after normalization to overall variability, REM sleep is more regular (ApEnsub = 1.224 +/- 0.092) than quiet sleep (ApEnsub = 1.448 +/- 0.071, P < 0.0001). Fifty percent of aborted-SIDS infants showed greater ApEn instability across quiet sleep than any normal infant exhibited, suggesting that autonomic regulation of heart rate occasionally becomes abnormal in a high-risk subject. There was an association between low ApEn values and aborted-SIDS events; 5 of 14 aborted-SIDS infants had at least one quiet sleep epoch with an ApEn value below the minimum of 45 normal-infant ApEn values.

  13. Photometric investigation of a very short period W UMa-type binary - Does CE Leonis have a large superluminous area?

    NASA Technical Reports Server (NTRS)

    Samec, Ronald G.; Su, Wen; Terrell, Dirk; Hube, Douglas P.

    1993-01-01

    A complete photometric analysis of BVRI Johnson-Cousins photometry of the high northern latitude galactic variable, CE Leo is presented. These observations were taken at Kitt Peak National Observatory on May 31, 1989-June 7, 1989. Three new precise epochs of minimum light were determined and a linear and a quadratic ephemeris were computed from these and previous data covering 28 years of observation. The light curves reveal that the system undergoes a brief 20 min totality in the primary eclipse, indicating that CE Leo is a W UMa W-type binary. A systemic velocity of about -40 km/s was determined. Standard magnitudes were found and a simultaneous solution of the B, V, R, I light curves was computed using the new Wilson-Devinney synthetic light curve code which has the capability of automatically adjusting star spots. The solution indicates that the system consists of two early K-type dwarfs in marginal contact with a fill-out factor less than 3 percent. Evidence for the presence of a large (45 deg radius) superluminous area on the cooler component is given.

  14. A Limit on the Warm Dark Matter Particle Mass from the Redshifted 21 cm Absorption Line

    NASA Astrophysics Data System (ADS)

    Safarzadeh, Mohammadtaher; Scannapieco, Evan; Babul, Arif

    2018-06-01

    The recent Experiment to Detect the Global Epoch of Reionization Signature (EDGES) collaboration detection of an absorption signal at a central frequency of ν = 78 ± 1 MHz points to the presence of a significant Lyα background by a redshift of z = 18. The timing of this signal constrains the dark matter particle mass (m χ ) in the warm dark matter (WDM) cosmological model. WDM delays the formation of small-scale structures, and therefore a stringent lower limit can be placed on m χ based on the presence of a sufficiently strong Lyα background due to star formation at z = 18. Our results show that coupling the spin temperature to the gas through Lyα pumping requires a minimum mass of m χ > 3 keV if atomic cooling halos dominate the star formation rate at z = 18, and m χ > 2 keV if {{{H}}}2 cooling halos also form stars efficiently at this redshift. These limits match or exceed the most stringent limits cited to date in the literature, even in the face of the many uncertainties regarding star formation at high redshift.

  15. The observable signature of late heating of the Universe during cosmic reionization.

    PubMed

    Fialkov, Anastasia; Barkana, Rennan; Visbal, Eli

    2014-02-13

    Models and simulations of the epoch of reionization predict that spectra of the 21-centimetre transition of atomic hydrogen will show a clear fluctuation peak, at a redshift and scale, respectively, that mark the central stage of reionization and the characteristic size of ionized bubbles. This is based on the assumption that the cosmic gas was heated by stellar remnants-particularly X-ray binaries-to temperatures well above the cosmic microwave background at that time (about 30 kelvin). Here we show instead that the hard spectra (that is, spectra with more high-energy photons than low-energy photons) of X-ray binaries make such heating ineffective, resulting in a delayed and spatially uniform heating that modifies the 21-centimetre signature of reionization. Rather than looking for a simple rise and fall of the large-scale fluctuations (peaking at several millikelvin), we must expect a more complex signal also featuring a distinct minimum (at less than a millikelvin) that marks the rise of the cosmic mean gas temperature above the microwave background. Observing this signal, possibly with radio telescopes in operation today, will demonstrate the presence of a cosmic background of hard X-rays at that early time.

  16. Outflow Channels Influencing Martian Climate: Global Circulation Model Simulations with Emplaced Water

    NASA Technical Reports Server (NTRS)

    Santiago, D. L.; Colaprete, A.; Haberle, R. M.; Sloan, L. C.; Asphaug, E. I.

    2005-01-01

    The existence of surface water on Mars in past geologic epochs is inferred on the basis of geomorphologic interpretation of spaceflight images, and is supported by the recent Mars Odyssey identification of ice-rich soils [1]. The Mars Exploration Rovers have provided further chemical evidence for past surface hydrologic activity [2]. One issue is whether this water-rich climate ever existed in a steady state, or whether it was triggered by catastrophic events such as large impacts [3], and/ or catastrophic outburst floods, the topic of consideration here.

  17. Recollimation shocks in the relativistic outflows of active galactic nuclei. Doctoral Thesis Award Lecture 2014

    NASA Astrophysics Data System (ADS)

    Fromm, C. M.

    2015-06-01

    We analysed the single-dish radio light curves of the blazar CTA 102 during its major flare around April 2006. The modelling of these data revealed a possible travelling shock-recollimation shock interaction during the flare. To verify this hypothesis, we used multi-epoch and multi-frequency very-long baseline interferometry (VLBI) observations and performed a detailed kinematic and spectral analysis. The results confirmed the hypothesis of a shock-shock interaction causing the 2006 radio flare and provided indications for additional recollimation shocks farther downstream.

  18. Prefazione al secondo volume di GERBERTVS

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    The act of the symposium Gerbertus Magister et Pastor held in Rome on May 2, 2011 and dedicated to the studies and to the activities of Gerbert of Aurillac, scientist, astronomer and pope. Here are presented the papers of Flavio G. Nuvolone, Paolo Rossi on historical subjects: Gerbert and king Lotarius, and the relationships between Gerbert and the Empire, with the choice of the name Sylvester. Finally Maurizio Chirri presents a study on the sources of the Geometry written by Gerbert, which contains also some astronomical methods as usual in the treatises of that epoch.

  19. UNUSUAL TRENDS IN SOLAR P-MODE FREQUENCIES DURING THE CURRENT EXTENDED MINIMUM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tripathy, S. C.; Jain, K.; Hill, F.

    2010-03-10

    We investigate the behavior of the intermediate-degree mode frequencies of the Sun during the current extended minimum phase to explore the time-varying conditions in the solar interior. Using contemporaneous helioseismic data from the Global Oscillation Network Group (GONG) and the Michelson Doppler Imager (MDI), we find that the changes in resonant mode frequencies during the activity minimum period are significantly greater than the changes in solar activity as measured by different proxies. We detect a seismic minimum in MDI p-mode frequency shifts during 2008 July-August but no such signature is seen in mean shifts computed from GONG frequencies. We alsomore » analyze the frequencies of individual oscillation modes from GONG data as a function of latitude and observe a signature of the onset of the solar cycle 24 in early 2009. Thus, the intermediate-degree modes do not confirm the onset of the cycle 24 during late 2007 as reported from the analysis of the low-degree Global Oscillations at Low Frequency frequencies. Further, both the GONG and MDI frequencies show a surprising anti-correlation between frequencies and activity proxies during the current minimum, in contrast to the behavior during the minimum between cycles 22 and 23.« less

  20. An Overview of Major Terrestrial, Celestial, and Temporal Coordinate Systems for Target Tracking

    DTIC Science & Technology

    2016-08-10

    interp and Subroutines) http://hpiers.obspm.fr/eop-pc/index.php?index=models General Software for Astronomy and Time Conversions The IAU’s Standards...of Fundamental Astronomy Software [146] http://www.iausofa.org Software for Optimal 2D Assignment An overview of 2D assignment algorithms; the... Astronomy (SOFA) library were used to change the epoch of the data. The points in red are at the epoch of the Hipparcos catalog (1994.25 TT), and 20

  1. Libration Point Orbit Utilization for Tactical Advantage in Communications, Surveillance, and Risk Mitigation

    DTIC Science & Technology

    2014-10-27

    Ephemeris model in the orbit analysis software Satellite Took Kit ( STK ). As the first step, a study was conducted to find the visibility coverage using...northern L1 and L3 halo orbits. Figure 55. Average visibility by latitude at different ephemeris epochs for an L1 orbiter from STK analysis . Figure...56. Average visibility by latitude at different ephemeris epochs for an L3 orbiter from STK analysis . Figure 57. Average percent visibility of the

  2. Set Up for Failure: The Use of US Security Force Assistance to Prepare Foreign Security Forces for Traditional Combat Operations

    DTIC Science & Technology

    2017-05-17

    Do the SFA lessons drawn from the unconventional warfare focus of the post-9-11 paradigm hold true across the spectrum of conflict, or are there...relevance. Do the SFA lessons drawn from the unconventional warfare focus of the post-9-11 paradigm hold true across the spectrum of conflict, or...traditional warfare is fought changes from epoch to epoch as technology, armament, and other factors change, but certain immutable principles hold true

  3. VizieR Online Data Catalog: Gould's Belt VLA Survey. II. Serpens region (Ortiz-Leon+, 2015)

    NASA Astrophysics Data System (ADS)

    Ortiz-Leon, G. N.; Loinard, L.; Mioduszewski, A. J.; Dzib, S. A.; Rodriguez, L. F.; Pech, G.; Rivera, J. L.; Torres, R. M.; Boden, A. F.; Hartmann, L.; Evans, N. J., II; Briceno, C.; Tobin, J.; Kounkel, M. A.; Gonzalez-Lopezlira, R. A.

    2015-09-01

    The Serpens molecular cloud and the Serpens South cluster were observed in the same observing sessions on three different epochs (2011 June 17, July 19, and September 12 UT), using 25 and 4 pointings, respectively, with the Jansky Very Large Array (JVLA) at 4.5 and 4.5GHz. The W40 region, on the other hand, was only observed on two epochs (2011 June 17 and July 16), using 13 pointings. (3 data files).

  4. The joint US/UK 1990 epoch world magnetic model

    NASA Technical Reports Server (NTRS)

    Quinn, John M.; Coleman, Rachel J.; Peck, Michael R.; Lauber, Stephen E.

    1991-01-01

    A detailed summary of the data used, analyses performed, modeling techniques employed, and results obtained in the course of the 1990 Epoch World Magnetic Modeling effort are given. Also, use and limitations of the GEOMAG algorithm are presented. Charts and tables related to the 1990 World Magnetic Model (WMM-90) for the Earth's main field and secular variation in Mercator and polar stereographic projections are presented along with useful tables of several magnetic field components and their secular variation on a 5-degree worldwide grid.

  5. The stratigraphy of Mars

    NASA Technical Reports Server (NTRS)

    Tanaka, Kenneth L.

    1986-01-01

    A global stratigraphy of Mars was developed from a global geologic map series derived from Viking images; the stratigraphy is composed of three maps. A new chronostratigraphic classification system which consists of lower, middle, and upper Noachian, Hesperian, and Amazonian systems is described. The crater-density boundaries of the chronostratigraphic units and the absolute ages of the Martian epochs aer estimated. The relative ages of major geologic units and featues are calculated and analyzed. The geologic history of Mars is summarized on the maps in terms of epochs.

  6. GEODYN programmer's guide, volume 2, part 2. [computer program for estimation of orbit and geodetic parameters

    NASA Technical Reports Server (NTRS)

    Mullins, N. E.; Dao, N. C.; Martin, T. V.; Goad, C. C.; Boulware, N. L.; Chin, M. M.

    1972-01-01

    A computer program for executive control routine for orbit integration of artificial satellites is presented. At the beginning of each arc, the program initiates required constants as well as the variational partials at epoch. If epoch needs to be reset to a previous time, the program negates the stepsize, and calls for integration backward to the desired time. After backward integration is completed, the program resets the stepsize to the proper positive quantity.

  7. Reinforcement of double dynamo waves as a source of solar activity and its prediction on millennium timescale

    NASA Astrophysics Data System (ADS)

    Popova, E.; Zharkova, V. V.; Shepherd, S. J.; Zharkov, S.

    2016-12-01

    Using the principal components of solar magnetic field variations derived from the synoptic maps for solar cycles 21-24 with Principal Components Analysis (PCA) (Zharkova et al, 2015) we confirm our previous prediction of the upcoming Maunder minimum to occur in cycles 25-27, or in 2020-2055. We also use a summary curve of the two eigen vectors of solar magnetic field oscillations (or two dynamo waves) to extrapolate solar activity backwards to the three millennia and to compare it with relevant historic and Holocene data. Extrapolation of the summary curve confirms the eight grand cycles of 350-400-years superimposed on 22 year-cycles caused by beating effect of the two dynamo waves generated in the two (deep and shallow) layers of the solar interior. The grand cycles in different periods comprise a different number of individual 22-year cycles; the longer the grand cycles the larger number of 22 year cycles and the smaller their amplitudes. We also report the super-grand cycle of about 2000 years often found in solas activity with spectral analysis. Furthermore, the summary curve reproduces a remarkable resemblance to the sunspot and terrestrial activity reported in the past: the recent Maunder Minimum (1645-1715), Dalton minimum (1790-1815), Wolf minimum (1200), Homeric minimum (800-900 BC), the Medieval Warmth Period (900-1200), the Roman Warmth Period (400-10BC) and so on. Temporal variations of these dynamo waves are modelled with the two layer mean dynamo model with meridional circulation revealing a remarkable resemblance of the butterfly diagram to the one derived for the last Maunder minimum in 17 century and predicting the one for the upcoming Maunder minimum in 2020-2055.

  8. Antibacterial and antioxidant activities of Musa sp. leaf extracts against multidrug resistant clinical pathogens causing nosocomial infection

    PubMed Central

    Karuppiah, Ponmurugan; Mustaffa, Muhammed

    2013-01-01

    Objective To investigate different Musa sp. leave extracts of hexane, ethyl acetate and methanol were evaluated for antibacterial activity against multi-drug resistant pathogens causing nosocomial infection by agar well diffusion method and also antioxidant activities. Methods The four different Musa species leaves were extracted with hexane, ethyl acetate and methanol. Antibacterial susceptibility test, minimum inhibitory concentration and minimum inhibitory bacterial concentration were determined by agar well diffusion method. Total phenolic content and in vitro antioxidant activity was determined. Results All the Musa sp. extracts showed moderate antibacterial activities expect Musa paradisiaca with the inhibition zone ranging from 8.0 to 18.6 mm. Among four species ethyl acetate extracts of Musa paradisiaca showed highest activity against tested pathogens particularly E. coli, P. aeruginosa and Citrobacter sp. The minimum inhibitory concentrations were within the value of 15.63- 250 µg/mL and minimum bactericidal concentrations were ranging from 31.25- 250 µg/mL. Antioxidant activity of Musa acuminate exhibited maximum activity among other three Musa species. Conclusions The present study concluded that among the different Musa species, Musa paradisiaca displayed efficient antibacterial activity followed by Musa acuminata against multi-drug resistant nosocomial infection causing pathogens. Further, an extensive study is needed to identify the bioactive compounds, mode of action and toxic effect in vivo of Musa sp. PMID:23998016

  9. Antibacterial and antioxidant activities of Musa sp. leaf extracts against multidrug resistant clinical pathogens causing nosocomial infection.

    PubMed

    Karuppiah, Ponmurugan; Mustaffa, Muhammed

    2013-09-01

    To investigate different Musa sp. leave extracts of hexane, ethyl acetate and methanol were evaluated for antibacterial activity against multi-drug resistant pathogens causing nosocomial infection by agar well diffusion method and also antioxidant activities. The four different Musa species leaves were extracted with hexane, ethyl acetate and methanol. Antibacterial susceptibility test, minimum inhibitory concentration and minimum inhibitory bacterial concentration were determined by agar well diffusion method. Total phenolic content and in vitro antioxidant activity was determined. All the Musa sp. extracts showed moderate antibacterial activities expect Musa paradisiaca with the inhibition zone ranging from 8.0 to 18.6 mm. Among four species ethyl acetate extracts of Musa paradisiaca showed highest activity against tested pathogens particularly E. coli, P. aeruginosa and Citrobacter sp. The minimum inhibitory concentrations were within the value of 15.63- 250 µg/mL and minimum bactericidal concentrations were ranging from 31.25- 250 µg/mL. Antioxidant activity of Musa acuminate exhibited maximum activity among other three Musa species. The present study concluded that among the different Musa species, Musa paradisiaca displayed efficient antibacterial activity followed by Musa acuminata against multi-drug resistant nosocomial infection causing pathogens. Further, an extensive study is needed to identify the bioactive compounds, mode of action and toxic effect in vivo of Musa sp.

  10. 40 CFR 60.2170 - Is there a minimum amount of monitoring data I must obtain?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... monitoring system quality assurance or quality control activities (including, as applicable, calibration... required monitoring system quality assurance or quality control activities including, as applicable... 40 Protection of Environment 7 2014-07-01 2014-07-01 false Is there a minimum amount of monitoring...

  11. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  12. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  13. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  14. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  15. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  16. 50 CFR 218.174 - Requirements for monitoring and reporting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...-based surveys shall be designed to maximize detections of marine mammals near mission activity event. (2... Navy to implement, at a minimum, the monitoring activities summarized below: (1) Visual Surveys: (i) The Holder of this Authorization shall conduct a minimum of 2 special visual surveys per year to...

  17. Statistical Comparison of Anomalous Cosmic Rays and Galactic Cosmic Rays during the Recently Consecutive Unusual Solar Cycles

    NASA Astrophysics Data System (ADS)

    Zhao, L.; Zhang, H.

    2014-12-01

    Anomalous cosmic rays (ACRs) carry crucial information on the coupling between solar wind and interstellar medium, as well as cosmic ray modulation within the heliosphere. Due to the distinct origins and modulation processes, the spectra and abundance of ACRs are significantly different from that of galactic cosmic rays (GCRs). Since the launch of NASA's ACE spacecraft in 1997, its CRIS and SIS instruments have continuously recorded GCR and ACR intensities of several elemental heavy-ions, spanning the whole cycle 23 and the cycle 24 maximum. Here we present a statistical comparison of ACR and GCR observed by ACE spacecraft and their possible relation to solar activity. While the differential flux of ACR also exhibits apparent anti-correlation with solar activity level, the flux of the latest prolonged solar minimum (year 2009) is approximately 5% lower than its previous solar minimum (year 1997). And the minimal level of ACR flux appears in year 2004, instead of year 2001 with the strongest solar activities. The negative indexes of the power law spectra within the energy range from 5 to 30 MeV/nuc also vary with time. The spectra get harder during the solar minimum but softer during the solar maximum. The approaching solar minimum of cycle 24 is believed to resemble the Dalton or Gleissberg Minimum with extremely low solar activity (Zolotova and Ponyavin, 2014). Therefore, the different characteristics of ACRs between the coming solar minimum and the previous minimum are also of great interest. Finally, we will also discuss the possible solar-modulation processes which is responsible for different modulation of ACR and GCR, especially the roles played by diffusion and drifts. The comparative analysis will provide valuable insights into the physical modulation process within the heliosphere under opposite solar polarity and variable solar activity levels.

  18. North-south asymmetric thermosphere response to geomagnetic storms caused by coronal mass ejections

    NASA Astrophysics Data System (ADS)

    Oliveira, D. M.; Zesta, E.; Schuck, P. W.; Sutton, E. K.

    2017-12-01

    We use CHAMP and GRACE density data in a statistical and superposed epoch analysis study to investigate the thermosphere global space and time response to CME-caused geomagnetic storms in the time period of September 2001 to September 2011. In order to account for solar cycle effects, we inter-calibrate both CHAMP and GRACE data against the Jacchia-Bowman 2008 (JB2008) empirical model under a regime of very low geomagnetic activity by fitting a polynomial fit with orthogonal expansion into the modeled density. We choose two different approaches related to physical effects of CME interactions with the magnetosphere. The zero epoch times are chosen as follows: in the first case, the instance of CME impact time associated with compression effects and, in the second case, the instance of time in which the IMF Bz turns suddenly southward, associated with the storm main phase onset. In general, in the second case, the thermosphere effects are more superposed in time in comparison to the effects of the first case. We find that, on average, large scale wave structures, presumably traveling atmospheric disturbances (TADs), propagate from auroral to equatorial regions in lag times as short as 3 hours. We also find that all local time regions, i.e., the global response, takes 2 more hours to occur. In addition, our findings show that there exists a strong north-south asymmetric heating, being most pronounced in the Southern Hemisphere in the moments preceding and following the zero epoch time. We attribute this effect to a combination of several factors that affect high latitude energy input into the upper atmosphere, such as seasons, IMF By component, and universal times, that is, the dipole longitude position during the developing of the storm main phase, the crucial time for energy input and subsequent thermosphere heating during geomagnetic storms.

  19. Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice.

    PubMed

    Roundtree, Harrison M; Simeone, Timothy A; Johnson, Chaz; Matthews, Stephanie A; Samson, Kaeli K; Simeone, Kristina A

    2016-02-01

    Comorbid sleep disorders occur in approximately one-third of people with epilepsy. Seizures and sleep disorders have an interdependent relationship where the occurrence of one can exacerbate the other. Orexin, a wake-promoting neuropeptide, is associated with sleep disorder symptoms. Here, we tested the hypothesis that orexin dysregulation plays a role in the comorbid sleep disorder symptoms in the Kcna1-null mouse model of temporal lobe epilepsy. Rest-activity was assessed using infrared beam actigraphy. Sleep architecture and seizures were assessed using continuous video-electroencephalography-electromyography recordings in Kcna1-null mice treated with vehicle or the dual orexin receptor antagonist, almorexant (100 mg/kg, intraperitoneally). Orexin levels in the lateral hypothalamus/perifornical region (LH/P) and hypothalamic pathology were assessed with immunohistochemistry and oxygen polarography. Kcna1-null mice have increased latency to rapid eye movement (REM) sleep onset, sleep fragmentation, and number of wake epochs. The numbers of REM and non-REM (NREM) sleep epochs are significantly reduced in Kcna1-null mice. Severe seizures propagate to the wake-promoting LH/P where injury is apparent (indicated by astrogliosis, blood-brain barrier permeability, and impaired mitochondrial function). The number of orexin-positive neurons is increased in the LH/P compared to wild-type LH/P. Treatment with a dual orexin receptor antagonist significantly increases the number and duration of NREM sleep epochs and reduces the latency to REM sleep onset. Further, almorexant treatment reduces the incidence of severe seizures and overall seizure burden. Interestingly, we report a significant positive correlation between latency to REM onset and seizure burden in Kcna1-null mice. Dual orexin receptor antagonists may be an effective sleeping aid in epilepsy, and warrants further study on their somnogenic and ant-seizure effects in other epilepsy models. © 2016 Associated Professional Sleep Societies, LLC.

  20. Performance of Transit Model Fitting in Processing Four Years of Kepler Science Data

    NASA Astrophysics Data System (ADS)

    Li, Jie; Burke, Christopher J.; Jenkins, Jon Michael; Quintana, Elisa V.; Rowe, Jason; Seader, Shawn; Tenenbaum, Peter; Twicken, Joseph D.

    2014-06-01

    We present transit model fitting performance of the Kepler Science Operations Center (SOC) Pipeline in processing four years of science data, which were collected by the Kepler spacecraft from May 13, 2009 to May 12, 2013. Threshold Crossing Events (TCEs), which represent transiting planet detections, are generated by the Transiting Planet Search (TPS) component of the pipeline and subsequently processed in the Data Validation (DV) component. The transit model is used in DV to fit TCEs and derive parameters that are used in various diagnostic tests to validate planetary candidates. The standard transit model includes five fit parameters: transit epoch time (i.e. central time of first transit), orbital period, impact parameter, ratio of planet radius to star radius and ratio of semi-major axis to star radius. In the latest Kepler SOC pipeline codebase, the light curve of the target for which a TCE is generated is initially fitted by a trapezoidal model with four parameters: transit epoch time, depth, duration and ingress time. The trapezoidal model fit, implemented with repeated Levenberg-Marquardt minimization, provides a quick and high fidelity assessment of the transit signal. The fit parameters of the trapezoidal model with the minimum chi-square metric are converted to set initial values of the fit parameters of the standard transit model. Additional parameters, such as the equilibrium temperature and effective stellar flux of the planet candidate, are derived from the fit parameters of the standard transit model to characterize pipeline candidates for the search of Earth-size planets in the Habitable Zone. The uncertainties of all derived parameters are updated in the latest codebase to take into account for the propagated errors of the fit parameters as well as the uncertainties in stellar parameters. The results of the transit model fitting of the TCEs identified by the Kepler SOC Pipeline, including fitted and derived parameters, fit goodness metrics and diagnostic figures, are included in the DV report and one-page report summary, which are accessible by the science community at NASA Exoplanet Archive. Funding for the Kepler Mission has been provided by the NASA Science Mission Directorate.

  1. A modified carrier-to-code leveling method for retrieving ionospheric observables and detecting short-term temporal variability of receiver differential code biases

    NASA Astrophysics Data System (ADS)

    Zhang, Baocheng; Teunissen, Peter J. G.; Yuan, Yunbin; Zhang, Xiao; Li, Min

    2018-03-01

    Sensing the ionosphere with the global positioning system involves two sequential tasks, namely the ionospheric observable retrieval and the ionospheric parameter estimation. A prominent source of error has long been identified as short-term variability in receiver differential code bias (rDCB). We modify the carrier-to-code leveling (CCL), a method commonly used to accomplish the first task, through assuming rDCB to be unlinked in time. Aside from the ionospheric observables, which are affected by, among others, the rDCB at one reference epoch, the Modified CCL (MCCL) can also provide the rDCB offsets with respect to the reference epoch as by-products. Two consequences arise. First, MCCL is capable of excluding the effects of time-varying rDCB from the ionospheric observables, which, in turn, improves the quality of ionospheric parameters of interest. Second, MCCL has significant potential as a means to detect between-epoch fluctuations experienced by rDCB of a single receiver.

  2. Interacting dark energy: Dynamical system analysis

    NASA Astrophysics Data System (ADS)

    Golchin, Hanif; Jamali, Sara; Ebrahimi, Esmaeil

    We investigate the impacts of interaction between dark matter (DM) and dark energy (DE) in the context of two DE models, holographic (HDE) and ghost dark energy (GDE). In fact, using the dynamical system analysis, we obtain the cosmological consequence of several interactions, considering all relevant component of universe, i.e. matter (dark and luminous), radiation and DE. Studying the phase space for all interactions in detail, we show the existence of unstable matter-dominated and stable DE-dominated phases. We also show that linear interactions suffer from the absence of standard radiation-dominated epoch. Interestingly, this failure resolved by adding the nonlinear interactions to the models. We find an upper bound for the value of the coupling constant of the interaction between DM and DE as b < 0.57in the case of holographic model, and b < 0.61 in the case of GDE model, to result in a cosmological viable matter-dominated epoch. More specifically, this bound is vital to satisfy instability and deceleration of matter-dominated epoch.

  3. Generalized Galileons: instabilities of bouncing and Genesis cosmologies and modified Genesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Libanov, M.; Moscow Institute of Physics and Technology,Institutskii per. 9, 141700 Dolgoprudny, Moscow Region; Mironov, S.

    2016-08-18

    We study spatially flat bouncing cosmologies and models with the early-time Genesis epoch in a popular class of generalized Galileon theories. We ask whether there exist solutions of these types which are free of gradient and ghost instabilities. We find that irrespectively of the forms of the Lagrangian functions, the bouncing models either are plagued with these instabilities or have singularities. The same result holds for the original Genesis model and its variants in which the scale factor tends to a constant as t→−∞. The result remains valid in theories with additional matter that obeys the Null Energy Condition andmore » interacts with the Galileon only gravitationally. We propose a modified Genesis model which evades our no-go argument and give an explicit example of healthy cosmology that connects the modified Genesis epoch with kination (the epoch still driven by the Galileon field, which is a conventional massless scalar field at that stage).« less

  4. Epochs of phase coherence between El Niño/Southern Oscillation and Indian monsoon

    NASA Astrophysics Data System (ADS)

    Maraun, D.; Kurths, J.

    2005-08-01

    We present a modern method used in nonlinear time series analysis to investigate the relation of two oscillating systems with respect to their phases, independently of their amplitudes. We study the difference of the phase dynamics between El Niño/Southern Oscillation (ENSO) and the Indian Monsoon on inter-annual time scales. We identify distinct epochs, especially two intervals of phase coherence, 1886-1908 and 1964-1980, corroborating earlier findings from a new point of view. A significance test shows that the coherence is very unlikely to be the result of stochastic fluctuations. We also detect so far unknown periods of coupling which are invisible to linear methods. These findings suggest that the decreasing correlation during the last decades might be a typical epoch of the ENSO/Monsoon system having occurred repeatedly. The high time resolution of the method enables us to present an interpretation of how volcanic radiative forcing could cause the coupling.

  5. Solar wind conditions leading to efficient radiation belt electron acceleration: A superposed epoch analysis

    DOE PAGES

    Li, W.; Thorne, R. M.; Bortnik, J.; ...

    2015-09-07

    In this study by determining preferential solar wind conditions leading to efficient radiation belt electron acceleration is crucial for predicting radiation belt electron dynamics. Using Van Allen Probes electron observations (>1 MeV) from 2012 to 2015, we identify a number of efficient and inefficient acceleration events separately to perform a superposed epoch analysis of the corresponding solar wind parameters and geomagnetic indices. By directly comparing efficient and inefficient acceleration events, we clearly show that prolonged southward Bz, high solar wind speed, and low dynamic pressure are critical for electron acceleration to >1 MeV energies in the heart of the outermore » radiation belt. We also evaluate chorus wave evolution using the superposed epoch analysis for the identified efficient and inefficient acceleration events and find that chorus wave intensity is much stronger and lasts longer during efficient electron acceleration events, supporting the scenario that chorus waves play a key role in MeV electron acceleration.« less

  6. Fifth Fundamental Catalogue (FK5). Part 1: Basic fundamental stars (Fricke, Schwan, and Lederle 1988): Documentation for the machine-readable version

    NASA Technical Reports Server (NTRS)

    Warren, Wayne H., Jr.

    1990-01-01

    The machine-readable version of the catalog, as it is currently being distributed from the Astronomical Data Center, is described. The Basic FK5 provides improved mean positions and proper motions for the 1535 classical fundamental stars that had been included in the FK3 and FK4 catalogs. The machine version of the catalog contains the positions and proper motions of the Basic FK5 stars for the epochs and equinoxes J2000.0 and B1950.0, the mean epochs of individual observed right ascensions and declinations used to determine the final positions, and the mean errors of the final positions and proper motions for the reported epochs. The cross identifications to other designations used for the FK5 stars that are given in the published catalog were not included in the original machine versions, but the Durchmusterung numbers have been added at the Astronomical Data Center.

  7. Star formation in globular clusters and dwarf galaxies and implications for the early evolution of galaxies

    NASA Technical Reports Server (NTRS)

    Lin, Douglas N. C.; Murray, Stephen D.

    1991-01-01

    Based upon the observed properties of globular clusters and dwarf galaxies in the Local Group, we present important theoretical constraints on star formation in these systems. These constraints indicate that protoglobular cluster clouds had long dormant periods and a brief epoch of violent star formation. Collisions between protocluster clouds triggered fragmentation into individual stars. Most protocluster clouds dispersed into the Galactic halo during the star formation epoch. In contrast, the large spread in stellar metallicity in dwarf galaxies suggests that star formation in their pregenitors was self-regulated: we propose the protocluster clouds formed from thermal instability in the protogalactic clouds and show that a population of massive stars is needed to provide sufficient UV flux to prevent the collapsing protogalactic clouds from fragmenting into individual stars. Based upon these constraints, we propose a unified scenario to describe the early epochs of star formation in the Galactic halo as well as the thick and thin components of the Galactic disk.

  8. Distinct roles of visual, parietal, and frontal motor cortices in memory-guided sensorimotor decisions.

    PubMed

    Goard, Michael J; Pho, Gerald N; Woodson, Jonathan; Sur, Mriganka

    2016-08-04

    Mapping specific sensory features to future motor actions is a crucial capability of mammalian nervous systems. We investigated the role of visual (V1), posterior parietal (PPC), and frontal motor (fMC) cortices for sensorimotor mapping in mice during performance of a memory-guided visual discrimination task. Large-scale calcium imaging revealed that V1, PPC, and fMC neurons exhibited heterogeneous responses spanning all task epochs (stimulus, delay, response). Population analyses demonstrated unique encoding of stimulus identity and behavioral choice information across regions, with V1 encoding stimulus, fMC encoding choice even early in the trial, and PPC multiplexing the two variables. Optogenetic inhibition during behavior revealed that all regions were necessary during the stimulus epoch, but only fMC was required during the delay and response epochs. Stimulus identity can thus be rapidly transformed into behavioral choice, requiring V1, PPC, and fMC during the transformation period, but only fMC for maintaining the choice in memory prior to execution.

  9. Circadian Activity Rhythms and Voluntary Ethanol Intake in Male and Female Ethanol-Preferring Rats: Effects of Long-Term Ethanol Access

    PubMed Central

    Rosenwasser, Alan M.; McCulley, Walter D.; Fecteau, Matthew

    2014-01-01

    Chronic alcohol (ethanol) intake alters fundamental properties of the circadian clock. While previous studies have reported significant alterations in free-running circadian period during chronic ethanol access, these effects are typically subtle and appear to require high levels of intake. In the present study we examined the effects of long-term voluntary ethanol intake on ethanol consumption and free-running circadian period in male and female, selectively bred ethanol-preferring P and HAD2 rats. In light of previous reports that intermittent access can result in escalated ethanol intake, an initial 2-week water-only baseline was followed by either continuous or intermittent ethanol access (i.e., alternating 15-day epochs of ethanol access and ethanol deprivation) in separate groups of rats. Thus, animals were exposed to either 135 days of continuous ethanol access or to five 15-day access periods alternating with four 15-day periods of ethanol deprivation. Animals were maintained individually in running-wheel cages under continuous darkness throughout the experiment to allow monitoring of free-running activity and drinking rhythms, and 10% (v/v) ethanol and plain water were available continuously via separate drinking tubes during ethanol access. While there were no initial sex differences in ethanol drinking, ethanol preference increased progressively in male P and HAD2 rats under both continuous and intermittent-access conditions, and eventually exceeded that seen in females. Free-running period shortened during the initial ethanol-access epoch in all groups, but the persistence of this effect showed complex dependence on sex, breeding line, and ethanol-access schedule. Finally, while females of both breeding lines displayed higher levels of locomotor activity than males, there was little evidence for modulation of activity level by ethanol access. These results are consistent with previous findings that chronic ethanol intake alters free-running circadian period, and show further that the development of chronobiological tolerance to ethanol may vary by sex and genotype. PMID:25281289

  10. Trial-by-Trial Motor Cortical Correlates of a Rapidly Adapting Visuomotor Internal Model

    PubMed Central

    Ryu, Stephen I.

    2017-01-01

    Accurate motor control is mediated by internal models of how neural activity generates movement. We examined neural correlates of an adapting internal model of visuomotor gain in motor cortex while two macaques performed a reaching task in which the gain scaling between the hand and a presented cursor was varied. Previous studies of cortical changes during visuomotor adaptation focused on preparatory and perimovement epochs and analyzed trial-averaged neural data. Here, we recorded simultaneous neural population activity using multielectrode arrays and focused our analysis on neural differences in the period before the target appeared. We found that we could estimate the monkey's internal model of the gain using the neural population state during this pretarget epoch. This neural correlate depended on the gain experienced during recent trials and it predicted the speed of the subsequent reach. To explore the utility of this internal model estimate for brain–machine interfaces, we performed an offline analysis showing that it can be used to compensate for upcoming reach extent errors. Together, these results demonstrate that pretarget neural activity in motor cortex reflects the monkey's internal model of visuomotor gain on single trials and can potentially be used to improve neural prostheses. SIGNIFICANCE STATEMENT When generating movement commands, the brain is believed to use internal models of the relationship between neural activity and the body's movement. Visuomotor adaptation tasks have revealed neural correlates of these computations in multiple brain areas during movement preparation and execution. Here, we describe motor cortical changes in a visuomotor gain change task even before a specific movement is cued. We were able to estimate the gain internal model from these pretarget neural correlates and relate it to single-trial behavior. This is an important step toward understanding the sensorimotor system's algorithms for updating its internal models after specific movements and errors. Furthermore, the ability to estimate the internal model before movement could improve motor neural prostheses being developed for people with paralysis. PMID:28087767

  11. Efficient synthesis of new 2,3-dihydrooxazole-spirooxindoles hybrids as antimicrobial agents.

    PubMed

    Tiwari, Shailendra; Pathak, Poonam; Sagar, Ram

    2016-05-15

    Two series of new 2,3-dihydrooxazole-spirooxindole derivatives were efficiently synthesized starting from N'-(2-oxoindolin-3-ylidene) benzohydrazide/N'-(2-oxoindolin-3-ylidene)-2-phenoxyacetohydrazide using designed synthetic route. Newly synthesized 2,3-dihydrooxazole-spirooxindole derivatives were screened for their antibacterial and antifungal activity against different pathogenic strain of bacteria and fungi. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) were determined for the test compounds as well as for reference standards. Compounds 4e, 4g, 7g have shown good antibacterial activity whereas compounds 4f, 7b, 7d have displayed better antifungal activity. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. IN-SYNC VI. Identification and Radial Velocity Extraction for 100+ Double-Lined Spectroscopic Binaries in the APOGEE/IN-SYNC Fields

    NASA Astrophysics Data System (ADS)

    Fernandez, M. A.; Covey, Kevin R.; De Lee, Nathan; Chojnowski, S. Drew; Nidever, David; Ballantyne, Richard; Cottaar, Michiel; Da Rio, Nicola; Foster, Jonathan B.; Majewski, Steven R.; Meyer, Michael R.; Reyna, A. M.; Roberts, G. W.; Skinner, Jacob; Stassun, Keivan; Tan, Jonathan C.; Troup, Nicholas; Zasowski, Gail

    2017-08-01

    We present radial velocity measurements for 70 high confidence, and 34 potential binary systems in fields containing the Perseus Molecular Cloud, Pleiades, NGC 2264, and the Orion A star-forming region. Eighteen of these systems have been previously identified as binaries in the literature. Candidate double-lined spectroscopic binaries (SB2s) are identified by analyzing the cross-correlation functions (CCFs) computed during the reduction of each APOGEE spectrum. We identify sources whose CCFs are well fit as the sum of two Lorentzians as likely binaries, and provide an initial characterization of the system based on the radial velocities indicated by that dual fit. For systems observed over several epochs, we present mass ratios and systemic velocities; for two systems with observations on eight or more epochs, and which meet our criteria for robust orbital coverage, we derive initial orbital parameters. The distribution of mass ratios for multi-epoch sources in our sample peaks at q = 1, but with a significant tail toward lower q values. Tables reporting radial velocities, systemic velocities, and mass ratios are provided online. We discuss future improvements to the radial velocity extraction method we employ, as well as limitations imposed by the number of epochs currently available in the APOGEE database. The Appendix contains brief notes from the literature on each system in the sample, and more extensive notes for select sources of interest.

  13. Time-dependent seismic tomography

    USGS Publications Warehouse

    Julian, B.R.; Foulger, G.R.

    2010-01-01

    Of methods for measuring temporal changes in seismic-wave speeds in the Earth, seismic tomography is among those that offer the highest spatial resolution. 3-D tomographic methods are commonly applied in this context by inverting seismic wave arrival time data sets from different epochs independently and assuming that differences in the derived structures represent real temporal variations. This assumption is dangerous because the results of independent inversions would differ even if the structure in the Earth did not change, due to observational errors and differences in the seismic ray distributions. The latter effect may be especially severe when data sets include earthquake swarms or aftershock sequences, and may produce the appearance of correlation between structural changes and seismicity when the wave speeds are actually temporally invariant. A better approach, which makes it possible to assess what changes are truly required by the data, is to invert multiple data sets simultaneously, minimizing the difference between models for different epochs as well as the rms arrival-time residuals. This problem leads, in the case of two epochs, to a system of normal equations whose order is twice as great as for a single epoch. The direct solution of this system would require twice as much memory and four times as much computational effort as would independent inversions. We present an algorithm, tomo4d, that takes advantage of the structure and sparseness of the system to obtain the solution with essentially no more effort than independent inversions require. No claim to original US government works Journal compilation ?? 2010 RAS.

  14. Bilateral hegu acupoints have the same effect on the heart rate variability of the healthy subjects.

    PubMed

    Guangjun, Wang; Yuying, Tian; Shuyong, Jia; Wenting, Zhou; Weibo, Zhang

    2014-01-01

    Background. The specificity of acupuncture points (acupoints) is one of the key concepts in traditional acupuncture theory, but the question of whether there is adequate scientific evidence to prove or disprove specificity has been vigorously debated in recent years. Acupoint laterality is an important aspect of acupoint specificity. Data is particularly scarce regarding the laterality of the same channel, namesake acupoint located on opposite sides of the body. Our previous study results suggest that Neiguan acupoint (PC6) has the laterality. The aim of this study was to investigate whether Hegu (LI4) also has laterality from the perspective of heart rate variability. Methods. A total of twenty-eight healthy female volunteers were recruited for this study and were randomly separated into the group I (n = 14) and the group II (n = 14) according to the register order. In the group I, left LI4 was stimulated in the first epoch and the right LI4 was stimulated in the second epoch. In the group II, right LI4 was stimulated in the first epoch and left LI4 was stimulated in the second epoch. Electrocardiogram was recorded and heart rate variability was analyzed. Results. The results show that there were no significant differences of heart rate variablity between the group I and the group II in the time domain and in the frequency domain. Conclusions. Bilateral Hegu acupoints have the same effect on the heart rate variability of the healthy subjects.

  15. Reducing Door-to-Needle Times using Toyota’s Lean Manufacturing Principles and Value Stream Analysis

    PubMed Central

    Ford, Andria L.; Williams, Jennifer A.; Spencer, Mary; McCammon, Craig; Khoury, Naim; Sampson, Tomoko; Panagos, Peter; Lee, Jin-Moo

    2012-01-01

    Background Earlier tPA treatment for acute ischemic stroke increases efficacy, prompting national efforts to reduce door-to-needle times (DNTs). We utilized lean process improvement methodology to develop a streamlined IV tPA protocol. Methods In early 2011, a multi-disciplinary team analyzed the steps required to treat acute ischemic stroke patients with IV tPA, utilizing value stream analysis (VSA). We directly compared the tPA-treated patients in the “pre-VSA” epoch to the “post-VSA” epoch with regard to baseline characteristics, protocol metrics, and clinical outcomes. Results The VSA revealed several tPA protocol inefficiencies: routing of patients to room, then to CT, then back to room; serial processing of work flow; and delays in waiting for lab results. On 3/1/2011, a new protocol incorporated changes to minimize delays: routing patients directly to head CT prior to patient room, utilizing parallel process work-flow, and implementing point-of-care labs. In the pre-and post-VSA epochs, 132 and 87 patients were treated with IV tPA, respectively. Compared to pre-VSA, DNTs and percent of patients treated ≤60 minutes from hospital arrival were improved in the post-VSA epoch: 60 min vs. 39 min (p<0.0001) and 52% vs. 78% (p<0.0001), respectively, with no change in symptomatic hemorrhage rate. Conclusions Lean process improvement methodology can expedite time-dependent stroke care, without compromising safety. PMID:23138440

  16. Antibacterial, antifungal and cytotoxic evaluation of some new quinazolinone derivatives

    PubMed Central

    Hassanzadeh, F.; Jafari, E.; Hakimelahi, G.H.; Khajouei, M. Rahmani; Jalali, M.; Khodarahmi, G.A.

    2012-01-01

    Quinazolinone ring system is renown because of its wide spectrum of pharmacological activities due to various substitutions on this ring system. In this study, the minimum inhibitory concentration of the synthesized compounds in our laboratory was determined by micro dilution Alamar Blue® Assay against six strains of bacteria (three Gram-positive and three Gram-negative) and three strains of fungi. Following a broth micro dilution minimum inhibitory concentration (MIC) test, Minimum Bactericidal Concentration (MBC) and Minimum Fungicidal Concentration (MFC) tests were performed. Cytotoxic effects of the compounds were measured using the MTT colorimetric assay on HeLa cell line. Results of antimicrobial screening showed that compounds had better bacteriostatic activity against Gram-negative bacteria. Results from MBC revealed that these compounds had more significant bacteriostatic than bactericidal activities. Nearly all screened compounds showed good activity against C. albicans and A. niger. Results from MFC indicated that these compounds had better fungistatic rather than fungicidal activities. The synthesized target molecules were found to exhibit different cytotoxicity in the range of 10 to 100 μM on HeLa cell line. Compounds 6 and 7 exhibited acceptable cytotoxicity approximately 50% at 10 μM concentration. PMID:23181085

  17. A longitudinal study of Caenorhabditis elegans larvae reveals a novel locomotion switch, regulated by Gαs signaling

    PubMed Central

    Nagy, Stanislav; Wright, Charles; Tramm, Nora; Labello, Nicholas; Burov, Stanislav; Biron, David

    2013-01-01

    Despite their simplicity, longitudinal studies of invertebrate models are rare. We thus sought to characterize behavioral trends of Caenorhabditis elegans, from the mid fourth larval stage through the mid young adult stage. We found that, outside of lethargus, animals exhibited abrupt switching between two distinct behavioral states: active wakefulness and quiet wakefulness. The durations of epochs of active wakefulness exhibited non-Poisson statistics. Increased Gαs signaling stabilized the active wakefulness state before, during and after lethargus. In contrast, decreased Gαs signaling, decreased neuropeptide release, or decreased CREB activity destabilized active wakefulness outside of, but not during, lethargus. Taken together, our findings support a model in which protein kinase A (PKA) stabilizes active wakefulness, at least in part through two of its downstream targets: neuropeptide release and CREB. However, during lethargus, when active wakefulness is strongly suppressed, the native role of PKA signaling in modulating locomotion and quiescence may be minor. DOI: http://dx.doi.org/10.7554/eLife.00782.001 PMID:23840929

  18. 40 CFR 60.2735 - Is there a minimum amount of monitoring data I must obtain?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... monitoring malfunctions, associated repairs, and required quality assurance or quality control activities for... periods, or required monitoring system quality assurance or control activities in calculations used to... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Is there a minimum amount of monitoring...

  19. 40 CFR 60.2735 - Is there a minimum amount of monitoring data I must obtain?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ....2770(o) of this part), and required monitoring system quality assurance or quality control activities... periods, and required monitoring system quality assurance or quality control activities including, as... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Is there a minimum amount of monitoring...

  20. Minimum structural requirements for cell membrane leakage-mediated anti-MRSA activity of macrocyclic bis(bibenzyl)s.

    PubMed

    Fujii, Kana; Morita, Daichi; Onoda, Kenji; Kuroda, Teruo; Miyachi, Hiroyuki

    2016-05-01

    Macrocyclic bis(bibenzyl)-type phenolic natural products, found exclusively in bryophytes, exhibit potent antibacterial activity towards methicillin-resistant Staphylococcus aureus (anti-MRSA activity). Here, in order to identify the minimum essential structure for cell membrane leakage-mediated anti-MRSA activity of these compounds, we synthesized acyclic fragment structures and evaluated their anti-MRSA activity. The activities of all of the acyclic fragments tested exhibited similar characteristics to those of the macrocycles, i.e., anti-MRSA bactericidal activity, an enhancing effect on influx and efflux of ethidium bromide (EtBr: fluorescent DNA-binder) in Staphylococcus aureus cells, and bactericidal activity towards a Staphylococcus aureus strain resistant to 2-phenoxyphenol (4). The latter result suggests that they have a different mechanism of action from 4, which is a FabI inhibitor previously proposed to be the minimum active fragment of riccardin-type macrocycles. Thus, cyclic structure is not a necessary condition for cell membrane leakage-mediated anti-MRSA activity of macrocyclic bis(bibenzyl)s. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Effect of dopamine injection on the hemocyte count and prophenoloxidase system of the white shrimp Litopenaeus vannamei

    NASA Astrophysics Data System (ADS)

    Pan, Luqing; Hu, Fawen; Zheng, Debin

    2011-09-01

    Effects of dopamine injection on the hemocyte count, phenoloxidase activity, serine proteinase activity, proteinase inhibitor activity and α2-macroglobulin-like activity in L. vannamei were studied. Results showed that dopamine injection resulted in a significant effect on the parameters measured ( P < 0.05), while no significant difference was observed in the control group (0.85% NaCl). In the experimental groups, the hemocyte count reached the minimum in 3 h; granular and semi-granular cells became stable after 12 h and hyaline cells and the total hemocyte count became stable after 18 h. Phenoloxidase activity reached the minimum in 6 h, and then became stable after 9 h. Serine protease activity and proteinase inhibitor activity reached the minimum in 3 h, and α2-macroglobulin-like activity reached the maximum in 3 h, and all the three parameters became stable after 12 h. The results suggest that the activating mechanisms of the proPO system triggered by dopamine are different from those triggered by invasive agents or spontaneously activated under a normal physical condition.

  2. Period Study and Analyses of 2017 Observations of the Totally Eclipsing, Solar Type Binary, MT Camelopardalis

    NASA Astrophysics Data System (ADS)

    Faulkner, Danny R.; Samec, Ronald G.; Caton, Daniel B.

    2018-06-01

    We report here on a period study and the analysis of BVRcIc light curves (taken in 2017) of MT Cam (GSC03737-01085), which is a solar type (T ~ 5500K) eclipsing binary. D. Caton observed MT Cam on 05, 14, 15, 16, and 17, December 2017 with the 0.81-m reflector at Dark Sky Observatory. Six times of minimum light were calculated from four primary eclipses and two secondary eclipses:HJD I = 24 58092.4937±0.0002, 2458102.74600±0.0021, 2458104.5769±0.0002, 2458104.9434±0.0029HJD II = 2458103.6610±0.0001, 2458104.7607±0.0020,Six times of minimum light were also calculated from data taken by Terrell, Gross, and Cooney, in their 2016 and 2004 observations (reported in IBVS #6166; TGC, hereafter). In addition, six more times of minimum light were taken from the literature. From all 18 times of minimum light, we determined the following light elements:JD Hel Min I=2458102.7460(4) + 0.36613937(5) EWe found the orbital period was constant over the 14 years spanning all observations. We note that TGC found a slightly increasing period. However, our results were obtained from a period study rather than comparison of observations from only two epochs by the Wilson-Devinney (W-D) Program. A BVRcIc Johnson-Cousins filtered simultaneous W-D Program solution gives a mass ratio (0.3385±0.0014) very nearly the same as TGC’s (0.347±0.003), and a component temperature difference of only ~40 K. As with TGC, no spot was needed in the modeling. Our modeling (beginning with Binary Maker 3.0 fits) was done without prior knowledge of TGC’s. This shows the agreement achieved when independent analyses are done with the W-D code. The present observations were taken 1.8 years later than the last curves by TGC, so some variation is expected.The Roche Lobe fill-out of the binary is ~13% and the inclination is ~83.5 degrees. The system is a shallow contact W-type W UMa Binary, albeit, the amplitudes of the primary and secondary eclipse are very nearly identical. An eclipse duration of ~21 minutes was determined for the secondary eclipse and the light curve solution. Additional and more detailed information is given in the poster paper.

  3. 3D change detection at street level using mobile laser scanning point clouds and terrestrial images

    NASA Astrophysics Data System (ADS)

    Qin, Rongjun; Gruen, Armin

    2014-04-01

    Automatic change detection and geo-database updating in the urban environment are difficult tasks. There has been much research on detecting changes with satellite and aerial images, but studies have rarely been performed at the street level, which is complex in its 3D geometry. Contemporary geo-databases include 3D street-level objects, which demand frequent data updating. Terrestrial images provides rich texture information for change detection, but the change detection with terrestrial images from different epochs sometimes faces problems with illumination changes, perspective distortions and unreliable 3D geometry caused by the lack of performance of automatic image matchers, while mobile laser scanning (MLS) data acquired from different epochs provides accurate 3D geometry for change detection, but is very expensive for periodical acquisition. This paper proposes a new method for change detection at street level by using combination of MLS point clouds and terrestrial images: the accurate but expensive MLS data acquired from an early epoch serves as the reference, and terrestrial images or photogrammetric images captured from an image-based mobile mapping system (MMS) at a later epoch are used to detect the geometrical changes between different epochs. The method will automatically mark the possible changes in each view, which provides a cost-efficient method for frequent data updating. The methodology is divided into several steps. In the first step, the point clouds are recorded by the MLS system and processed, with data cleaned and classified by semi-automatic means. In the second step, terrestrial images or mobile mapping images at a later epoch are taken and registered to the point cloud, and then point clouds are projected on each image by a weighted window based z-buffering method for view dependent 2D triangulation. In the next step, stereo pairs of the terrestrial images are rectified and re-projected between each other to check the geometrical consistency between point clouds and stereo images. Finally, an over-segmentation based graph cut optimization is carried out, taking into account the color, depth and class information to compute the changed area in the image space. The proposed method is invariant to light changes, robust to small co-registration errors between images and point clouds, and can be applied straightforwardly to 3D polyhedral models. This method can be used for 3D street data updating, city infrastructure management and damage monitoring in complex urban scenes.

  4. Antioxidant response of ridgetail white prawn Exopalaemon carinicauda to harmful dinoflagellate Prorocentrum minimum exposure and its histological change

    NASA Astrophysics Data System (ADS)

    Mu, Cuimin; Ren, Xianyun; Ge, Qianqian; Wang, Jiajia; Li, Jian

    2017-04-01

    The dinoflagellate Prorocentrum minimum, one of the most widespread red tide causing species, affects marine aquaculture and ecosystems worldwide. In this study, ridgetail white prawn Exopalaemon carinicauda were exposed to P. minimum cells (5 × 104 cells mL-1) to investigate its harmful effects on the shrimp. Antioxidant activities and histological changes were used as indicators of health status of the shrimp. In 72 hours, the mortality of E. carinicauda was not affected, but its antioxidant response and histology were statistically different from those of control. Elevated superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities and depressed catalase (CAT) activity were observed in gill; while increased SOD, glutathione S-transferase (GST), CAT activities and modulated GPX activity were observed in hepatopancreas. Thus, antioxidant activities in gill and hepatopancreas seem to respond differentially to harmful alga exposure. Increased malondialdehyde (MDA) content in early a few hours indicates the damage of the antioxidant defense system. Although MDA content recovered to a low level thereafter, a series of histological abnormalities including accumulation or infiltration of hemocytes, tissue lesions and necrosis were discovered in gill and hepatopancreas. Exposure to P. minimum induced sublethal effects on E. carinicauda, including temporary oxidative damage and histological injury.

  5. FIRST ZEEMAN DOPPLER IMAGING OF A COOL STAR USING ALL FOUR STOKES PARAMETERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosén, L.; Kochukhov, O.; Wade, G. A.

    Magnetic fields are ubiquitous in active cool stars, but they are in general complex and weak. Current Zeeman Doppler imaging (ZDI) studies of cool star magnetic fields chiefly employ circular polarization observations because linear polarization is difficult to detect and requires a more sophisticated radiative transfer modeling to interpret. But it has been shown in previous theoretical studies, and in the observational analyses of magnetic Ap stars, that including linear polarization in the magnetic inversion process makes it possible to correctly recover many otherwise lost or misinterpreted magnetic features. We have obtained phase-resolved observations in all four Stokes parameters ofmore » the RS CVn star II Peg at two separate epochs. Here we present temperature and magnetic field maps reconstructed for this star using all four Stokes parameters. This is the very first such ZDI study of a cool active star. Our magnetic inversions reveal a highly structured magnetic field topology for both epochs. The strength of some surface features is doubled or even quadrupled when linear polarization is taken into account. The total magnetic energy of the reconstructed field map also becomes about 2.1–3.5 times higher. The overall complexity is also increased as the field energy is shifted toward higher harmonic modes when four Stokes parameters are used. As a consequence, the potential field extrapolation of the four Stokes parameter ZDI results indicates that magnetic field becomes weaker at a distance of several stellar radii due to a decrease of the large-scale field component.« less

  6. Amphetamine Exerts Dose-Dependent Changes in Prefrontal Cortex Attractor Dynamics during Working Memory

    PubMed Central

    Balaguer-Ballester, Emili; Seamans, Jeremy K.; Phillips, Anthony G.; Durstewitz, Daniel

    2015-01-01

    Modulation of neural activity by monoamine neurotransmitters is thought to play an essential role in shaping computational neurodynamics in the neocortex, especially in prefrontal regions. Computational theories propose that monoamines may exert bidirectional (concentration-dependent) effects on cognition by altering prefrontal cortical attractor dynamics according to an inverted U-shaped function. To date, this hypothesis has not been addressed directly, in part because of the absence of appropriate statistical methods required to assess attractor-like behavior in vivo. The present study used a combination of advanced multivariate statistical, time series analysis, and machine learning methods to assess dynamic changes in network activity from multiple single-unit recordings from the medial prefrontal cortex (mPFC) of rats while the animals performed a foraging task guided by working memory after pretreatment with different doses of d-amphetamine (AMPH), which increases monoamine efflux in the mPFC. A dose-dependent, bidirectional effect of AMPH on neural dynamics in the mPFC was observed. Specifically, a 1.0 mg/kg dose of AMPH accentuated separation between task-epoch-specific population states and convergence toward these states. In contrast, a 3.3 mg/kg dose diminished separation and convergence toward task-epoch-specific population states, which was paralleled by deficits in cognitive performance. These results support the computationally derived hypothesis that moderate increases in monoamine efflux would enhance attractor stability, whereas high frontal monoamine levels would severely diminish it. Furthermore, they are consistent with the proposed inverted U-shaped and concentration-dependent modulation of cortical efficiency by monoamines. PMID:26180194

  7. Propagating wave and irregular dynamics: Spatiotemporal patterns of cholinergic theta oscillations in neocortex, in vitro

    PubMed Central

    Bao, Weili; Wu, Jian-young

    2010-01-01

    Neocortical “theta” oscillation (5- 12 Hz) has been observed in animals and human subjects but little is known about how the oscillation is organized in the cortical intrinsic networks. Here we use voltage-sensitive dye and optical imaging to study a carbachol/bicuculline induced theta (~8 Hz) oscillation in rat neocortical slices. The imaging has large signal-to-noise ratio, allowing us to map the phase distribution over the neocortical tissue during the oscillation. The oscillation was organized as spontaneous epochs and each epoch was composed of a “first spike”, a “regular” period (with relatively stable frequency and amplitude) and an “irregular” period (with variable frequency and amplitude) of oscillations. During each cycle of the regular oscillation one wave of activation propagated horizontally (parallel to the cortical lamina) across the cortical section at a velocity of ~50 mm/sec. Vertically the activity was synchronized through all cortical layers. This pattern of one propagating wave associated with one oscillation cycle was seen during all the regular cycles. The oscillation frequency varied noticeably at two neighboring horizontal locations (330 μm apart), suggesting that the oscillation is locally organized and each local oscillator is about equal or less than 300 μm wide horizontally. During irregular oscillations the spatiotemporal patterns were complex and sometimes the vertical synchronization decomposed, suggesting a de-coupling among local oscillators. Our data suggested that neocortical theta oscillation is sustained by multiple local oscillators. The coupling regime among the oscillators may determine the spatiotemporal pattern and switching between propagating waves and irregular patterns. PMID:12612003

  8. [Activities of Bay Area Research Corporation

    NASA Technical Reports Server (NTRS)

    2003-01-01

    During the final year of this effort the HALFSHEL code was converted to work on a fast single processor workstation from it s parallel configuration. This was done because NASA Ames NAS facility stopped supporting space science and we no longer had access to parallel computer time. The single processor version of HALFSHEL was upgraded to address low density cells by using a a 3-D SOR solver to solve the equation Delta central dot E = 0. We then upgraded the ionospheric load packages to provide a multiple species load of the ionosphere out to 1.4 Rm. With these new tools we began to perform a series of simulations to address the major topic of this research effort; determining the loss rate of O(sup +) and O2(sup +) from Mars. The simulations used the nominal Parker spiral field and in one case used a field perpendicular to the solar wind flow. The simulations were performed for three different solar EUV fluxes consistent with the different solar evolutionary states believed to exist before today. The 1 EUV case is the nominal flux of today. The 3 EUV flux is called Epoch 2 and has three times the flux of todays. The 6 EUV case is Epoch 3 and has 6 times the EUV flux of today.

  9. Discovery of a very Lyman-α-luminous quasar at z = 6.62.

    PubMed

    Koptelova, Ekaterina; Hwang, Chorng-Yuan; Yu, Po-Chieh; Chen, Wen-Ping; Guo, Jhen-Kuei

    2017-02-02

    Distant luminous quasars provide important information on the growth of the first supermassive black holes, their host galaxies and the epoch of reionization. The identification of quasars is usually performed through detection of their Lyman-α line redshifted to 0.9 microns at z > 6.5. Here, we report the discovery of a very Lyman-α luminous quasar, PSO J006.1240 + 39.2219 at redshift z = 6.618, selected based on its red colour and multi-epoch detection of the Lyman-α emission in a single near-infrared band. The Lyman-α line luminosity of PSO J006.1240 + 39.2219 is unusually high and estimated to be 0.8 × 10 12 Solar luminosities (about 3% of the total quasar luminosity). The Lyman-α emission of PSO J006.1240 + 39.2219 shows fast variability on timescales of days in the quasar rest frame, which has never been detected in any of the known high-redshift quasars. The high luminosity of the Lyman-α line, its narrow width and fast variability resemble properties of local Narrow-Line Seyfert 1 galaxies which suggests that the quasar is likely at the active phase of the black hole growth accreting close or even beyond the Eddington limit.

  10. Discovery of a very Lyman-α-luminous quasar at z = 6.62

    PubMed Central

    Koptelova, Ekaterina; Hwang, Chorng-Yuan; Yu, Po-Chieh; Chen, Wen-Ping; Guo, Jhen-Kuei

    2017-01-01

    Distant luminous quasars provide important information on the growth of the first supermassive black holes, their host galaxies and the epoch of reionization. The identification of quasars is usually performed through detection of their Lyman-α line redshifted to 0.9 microns at z > 6.5. Here, we report the discovery of a very Lyman-α luminous quasar, PSO J006.1240 + 39.2219 at redshift z = 6.618, selected based on its red colour and multi-epoch detection of the Lyman-α emission in a single near-infrared band. The Lyman-α line luminosity of PSO J006.1240 + 39.2219 is unusually high and estimated to be 0.8 × 1012 Solar luminosities (about 3% of the total quasar luminosity). The Lyman-α emission of PSO J006.1240 + 39.2219 shows fast variability on timescales of days in the quasar rest frame, which has never been detected in any of the known high-redshift quasars. The high luminosity of the Lyman-α line, its narrow width and fast variability resemble properties of local Narrow-Line Seyfert 1 galaxies which suggests that the quasar is likely at the active phase of the black hole growth accreting close or even beyond the Eddington limit. PMID:28150701

  11. Factors associated with respiration induced variability in cerebral blood flow velocity.

    PubMed Central

    Coughtrey, H; Rennie, J M; Evans, D H; Cole, T J

    1993-01-01

    A consecutive cohort of 73 very low birthweight infants was studied to determine the presence or absence of beat to beat variability in the velocity of blood flow in the cerebral circulation and its relation with respiration. One minute epochs of information included recordings of cerebral blood flow velocity estimated with Doppler ultrasound, blood pressure, spontaneous respiratory activity, and ventilator cycling. Fourier transformation was used to resolve the frequencies present within the one minute epochs and to classify the cerebral blood flow velocity as showing the presence or absence of any respiratory associated variability. A total of 249 recordings was made on days 1, 2, 3, and 7. Forty seven infants showed respiratory variability in cerebral blood flow velocity on 97 occasions, usually during the first day of life. The infants with respiratory associated variability were of lower gestational age and when the respiratory associated variability was present they were more likely to be ventilated and receiving higher inspired oxygen; these associations were shown to be independent of gestational age. There was no significant independent association with brain injury, cerebral blood flow velocity (cm/s), or blood pressure (mm Hg). The findings suggest that artificial ventilation may entrain normal respiratory associated variability in the cerebral circulation but do not provide evidence that it is harmful. PMID:8466269

  12. Electrocorticography reveals beta desynchronization in the basal ganglia-cortical loop during rest tremor in Parkinson’s disease

    PubMed Central

    Qasim, Salman E.; de Hemptinne, Coralie; Swann, Nicole C.; Miocinovic, Svjetlana; Ostrem, Jill L.; Starr, Philip A.

    2015-01-01

    The pathophysiology of rest tremor in Parkinson’s disease (PD) is not well understood, and its severity does not correlate with the severity of other cardinal signs of PD. We hypothesized that tremor-related oscillatory activity in the basal-ganglia-thalamocortical loop might serve as a compensatory mechanism for the excessive beta band synchronization associated with the parkinsonian state. We recorded electrocorticography (ECoG) from the sensorimotor cortex and local field potentials (LFP) from the subthalamic nucleus (STN) in patients undergoing lead implantation for deep brain stimulation (DBS). We analyzed differences in measures of network synchronization during epochs of spontaneous rest tremor, versus epochs without rest tremor, occurring in the same subjects. The presence of tremor was associated with reduced beta power in the cortex and STN. Cortico-cortical coherence and phase-amplitude coupling (PAC) decreased during rest tremor, as did basal ganglia-cortical coherence in the same frequency band. Cortical broadband gamma power was not increased by tremor onset, in contrast to the movement-related gamma increase typically observed at the onset of voluntary movement. These findings suggest that the cortical representation of rest tremor is distinct from that of voluntary movement, and support a model in which tremor acts to decrease beta band synchronization within the basal ganglia-cortical loop. PMID:26639855

  13. EEG alpha activity and hallucinatory experience during sensory deprivation.

    PubMed

    Hayashi, M; Morikawa, T; Hori, T

    1992-10-01

    The relationship between hallucinatory experiences under sensory deprivation and EEG alpha activities was studied. Each of seven male students lived alone in an air conditioned, soundproof dark room for 72 hours. When hallucinatory experiences occurred, the students pressed a button at once. If they could not press the button during the experience, they were required to press it two times when the hallucinatory experience was finished. Spectral analysis was performed on the consecutive EEG samples from just before button-presses to 10 min. before them, and the average alpha band amplitudes were obtained for the four epochs (0-.5, .5-2, 2-5, 5-10 min.). For the single button-presses, the amplitude of alpha band increased 2 min. before the button-presses. Right-hemisphere EEG activation was observed in the occipital area for the double button-presses. The results suggest an association between the hallucinatory experiences under sensory deprivation and the amount of EEG alpha activity.

  14. Hot Jupiters and Hot Spots: The Short- and Long-Term Chromospheric Activity on Stars with Giant Planets

    NASA Astrophysics Data System (ADS)

    Shkolnik, E.; Walker, G. A. H.; Bohlender, D. A.; Gu, P.-G.; Kürster, M.

    2005-04-01

    We monitored the chromospheric activity in the Ca II H and K lines of 13 solar-type stars (including the Sun): 8 of them over 3 years at the Canada-France-Hawaii Telescope (CFHT) and 5 in a single run at the Very Large Telescope (VLT). A total of 10 of the 13 targets have close planetary companions. All of the stars observed at the CFHT show long-term (months to years) changes in H and K intensity levels. Four stars display short-term (days) cyclical activity. For two, HD 73256 and κ1 Cet, the activity is likely associated with an active region rotating with the star; however, the flaring in excess of the rotational modulation may be associated with a hot Jupiter. A planetary companion remains a possibility for κ1 Cet. For the other two, HD 179949 and υ And, the cyclic variation is synchronized to the hot Jupiter's orbit. For both stars this synchronicity with the orbit is clearly seen in two out of three epochs. The effect is only marginal in the third epoch at which the seasonal level of chromospheric activity had changed for both stars. Short-term chromospheric activity appears weakly dependent on the mean K line reversal intensities for the sample of 13 stars. In addition, a suggestive correlation exists between this activity and the Mpsini of the star's hot Jupiter. Because of their small separation (<=0.1 AU), many of the hot Jupiters lie within the Alfvén radius of their host stars, which allows a direct magnetic interaction with the stellar surface. We discuss the conditions under which a planet's magnetic field might induce activity on the stellar surface and why no such effect was seen for the prime candidate, τ Boo. This work opens up the possibility of characterizing planet-star interactions, with implications for extrasolar planet magnetic fields and the energy contribution to stellar atmospheres. Based on observations collected at the Canada-France-Hawaii Telescope operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique of France, and the University of Hawaii, as well as data from the European Southern Observatory's Very Large Telescope, Chile (programme ESO 73.C-0694).

  15. Unifying inflation with ΛCDM epoch in modified f(R) gravity consistent with Solar System tests

    NASA Astrophysics Data System (ADS)

    Nojiri, Shin'ichi; Odintsov, Sergei D.

    2007-12-01

    We suggest two realistic f(R) and one F(G) modified gravities which are consistent with local tests and cosmological bounds. The typical property of such theories is the presence of the effective cosmological constant epochs in such a way that early-time inflation and late-time cosmic acceleration are naturally unified within single model. It is shown that classical instability does not appear here and Newton law is respected. Some discussion of possible anti-gravity regime appearance and related modification of the theory is done.

  16. Will nonlinear peculiar velocity and inhomogeneous reionization spoil 21 cm cosmology from the epoch of reionization?

    PubMed

    Shapiro, Paul R; Mao, Yi; Iliev, Ilian T; Mellema, Garrelt; Datta, Kanan K; Ahn, Kyungjin; Koda, Jun

    2013-04-12

    The 21 cm background from the epoch of reionization is a promising cosmological probe: line-of-sight velocity fluctuations distort redshift, so brightness fluctuations in Fourier space depend upon angle, which linear theory shows can separate cosmological from astrophysical information. Nonlinear fluctuations in ionization, density, and velocity change this, however. The validity and accuracy of the separation scheme are tested here for the first time, by detailed reionization simulations. The scheme works reasonably well early in reionization (≲40% ionized), but not late (≳80% ionized).

  17. Erratum: "Discovery of a Second Millisecond Accreting Pulsar: XTE J1751-305"

    NASA Technical Reports Server (NTRS)

    Markwardt, Craig; Swank, J. H.; Strohmayer, T. E.; in 'tZand, J. J. M.; Marshall, F. E.

    2007-01-01

    The original Table 1 ("Timing Parameters of XTE J1751-305") contains one error. The epoch of pulsar mean longitude 90deg is incorrect due to a numerical conversion error in the preparation of the original table text. A corrected version of Table 1 is shown. For reference, the epoch of the ascending node is also included. The correct value was used in all of the analysis leading up to the paper. As T(sub 90) is a purely fiducial reference time, the scientific conclusions of the paper are unchanged.

  18. Program and Portfolio Tradeoffs Under Uncertainty Using Epoch-Era Analysis: A Case Application to Carrier Strike Group Design

    DTIC Science & Technology

    2015-05-01

    Warn in_&_ Weapon system detection Electromagnetic ~stem Sea superiority Air Superiority undersea Su_e_erior~ Combat Search and Rescue Anti-Ship...izatian 5. Sy.ste m-Level Capability Assessment ~----------------------------- A tte rn ative s. Evaluat ion 6. De sign-Epoch-Era Trade space...I A tte r n ative s. An a lysis. : 10. Single-Er a 9 . Er a Con.stru ct ion Analysis 11. M utti-Era Analysis I I I I I I I I I I I

  19. X-ray emission at a position consistent with SN2009ip

    NASA Astrophysics Data System (ADS)

    Margutti, R.; Soderberg, A.

    2012-10-01

    We observed SN2009ip for a total of ~93 ks with Swift/XRT. We split the observation into two epochs. The first epoch comprises data acquired between September 10th and October 1st, for a total of ~53 ks of exposure. No source is detected at the position of the SN, with a 3 sigma upper limit of 3.3d-4 counts/sec in the 0.3-10 keV energy band (a similar limit has been reported by Campana Atel #4444).

  20. The effect of solar activity on ill and healthy people under conditions of neurous and emotional stresses

    NASA Astrophysics Data System (ADS)

    Zakharov, I. G.; Tyrnov, O. F.

    2001-01-01

    It is commonly agreed that solar activity has adverse effects first of all on enfeebled and ill organisms. In our study we have traced that under conditions of neurous and emotional stresses (at work, in the street, and in cars) the effect may be larger (˜ 30 %) for healthy people. Our calculations have been carried out applying the epoch-superposition method, spectrum and correlation analyses to daily data over a 1992 to 1994 period from three independent databases (Kharkiv City) on patients (adults and children) suffering from mental diseases and physical traumas. The effect is most marked during the recovery phase of geomagnetic storms and accompanied by the inhibition in the central nervous system.

  1. Apes in the Anthropocene: flexibility and survival.

    PubMed

    Hockings, Kimberley J; McLennan, Matthew R; Carvalho, Susana; Ancrenaz, Marc; Bobe, René; Byrne, Richard W; Dunbar, Robin I M; Matsuzawa, Tetsuro; McGrew, William C; Williamson, Elizabeth A; Wilson, Michael L; Wood, Bernard; Wrangham, Richard W; Hill, Catherine M

    2015-04-01

    We are in a new epoch, the Anthropocene, and research into our closest living relatives, the great apes, must keep pace with the rate that our species is driving change. While a goal of many studies is to understand how great apes behave in natural contexts, the impact of human activities must increasingly be taken into account. This is both a challenge and an opportunity, which can importantly inform research in three diverse fields: cognition, human evolution, and conservation. No long-term great ape research site is wholly unaffected by human influence, but research at those that are especially affected by human activity is particularly important for ensuring that our great ape kin survive the Anthropocene. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Automatic EEG artifact removal: a weighted support vector machine approach with error correction.

    PubMed

    Shao, Shi-Yun; Shen, Kai-Quan; Ong, Chong Jin; Wilder-Smith, Einar P V; Li, Xiao-Ping

    2009-02-01

    An automatic electroencephalogram (EEG) artifact removal method is presented in this paper. Compared to past methods, it has two unique features: 1) a weighted version of support vector machine formulation that handles the inherent unbalanced nature of component classification and 2) the ability to accommodate structural information typically found in component classification. The advantages of the proposed method are demonstrated on real-life EEG recordings with comparisons made to several benchmark methods. Results show that the proposed method is preferable to the other methods in the context of artifact removal by achieving a better tradeoff between removing artifacts and preserving inherent brain activities. Qualitative evaluation of the reconstructed EEG epochs also demonstrates that after artifact removal inherent brain activities are largely preserved.

  3. Centaurus A, the core of the problem

    NASA Technical Reports Server (NTRS)

    Tingay, S. J.; Jauncey, D. L.; Preston, R. A.; Reynolds, J. E.; Meier, D. L.; Tzioumis, A. K.; Jones, D. L.; King, E. A.; Amy, S. W.; Biggs, J. D.

    1994-01-01

    The bright, peculiar elliptical galaxy Centaurus A (NGC 5128, PKS 1322-427) was one of the first extragalactic radio sources to be optically identified (Bolton et al. 1949). At a distance of 4 Mpc, Centaurus A is the closest active radio galaxy and affords the highest linear imaging resolution (1 mas approximately equal to 0.02 pc) and hence the best prospects for studying an active nucleus close to the central radio source. We present the results of multi-epoch, 8.4-GHz, very long baseline interferometry (VLBI), imaging observations of the nucleus made over the past three years. The nucleus possesses a core-jet structure where the inner portion of the jet shows apparent linear motion with a velocity substantially less than the speed of light.

  4. The MagAO Giant Accreting Protoplanet Survey (GAPlanetS): Recent Results

    NASA Astrophysics Data System (ADS)

    Follette, Katherine; Close, Laird; Males, Jared; Morzinski, Katie; Leonard, Clare; MagAO

    2018-01-01

    I will summarize recent results of the MagAO Giant Accreting Protoplant Survey (GAPlanetS), a search for accreting protoplanets at H-alpha inside of transitional disk gaps. These young, centrally-cleared circumstellar disks are often hosted by stars that are still actively accreting, making it likely that any planets that lie in their central cavities will also be actively accreting. Through differential imaging at Hydrogen-alpha using Magellan's visible light adaptive optics system, we have completed the first systematic search for H-alpha emission from accreting protoplanets in fifteen bright Southern hemisphere transitional disks. I will present results from this survey, including a second epoch on the LkCa 15 system that shows several accreting protoplanet candidates.

  5. Sizes and locations of coronal mass ejections - SMM observations from 1980 and 1984-1989

    NASA Technical Reports Server (NTRS)

    Hundhausen, A. J.

    1993-01-01

    A statistical description of the sizes and locations of 1209 mass ejections observed with the SMM coronagraph/polarimeter in 1980 and 1984-1989 is presented. The average width of the coronal mass ejections detected with this instrument was close to 40 deg in angle for the entire period of SMM observations. No evidence was found for a significant change in mass ejection widths as reported by Howard et al. (1986). There is clear evidence for changes in the latitude distribution of mass ejections over this epoch. Mass ejections occurred over a much wider range of latitudes at the times of high solar activity (1980 and 1989) than at times of low activity (1985-1986).

  6. Intermittent behavior of galactic dynamo activities

    NASA Technical Reports Server (NTRS)

    Ko, C. M.; Parker, E. N.

    1989-01-01

    Recent observations by Beck and Golla of far-infrared and radio continuum emission from nearby spiral galaxies suggest that the galactic magnetic field strength is connected to the current star formation rate. The role of star formation on the generation of large-scale galactic magnetic field is studied in this paper. Using a simple galactic model, it is shown how the galactic dynamo depends strongly on the turbulent velocity of the interstellar medium. When the star formation efficiency is high, the ISM is churned which in turn amplifies the galactic magnetic field. Between active star formation epochs, the magnetic field is in dormant state and decays at a negligible rate. If density waves trigger star formation, then they also turn on the otherwise dormant dynamo.

  7. 13 CFR 106.202 - What are the minimum requirements applicable to Cosponsored Activities?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What are the minimum requirements applicable to Cosponsored Activities? 106.202 Section 106.202 Business Credit and Assistance SMALL BUSINESS... constitute or imply an endorsement by SBA of any Cosponsor or any Cosponsor's products or services; (c) Any...

  8. 40 CFR 60.2170 - Is there a minimum amount of monitoring data I must obtain?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...-control periods, or required monitoring system quality assurance or control activities in calculations... 40 Protection of Environment 7 2012-07-01 2012-07-01 false Is there a minimum amount of monitoring..., 2001 Monitoring § 60.2170 Is there a minimum amount of monitoring data I must obtain? (a) Except for...

  9. 40 CFR 60.2170 - Is there a minimum amount of monitoring data I must obtain?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Is there a minimum amount of monitoring..., 2001 Monitoring § 60.2170 Is there a minimum amount of monitoring data I must obtain? (a) Except for monitor malfunctions, associated repairs, and required quality assurance or quality control activities...

  10. 40 CFR 60.2170 - Is there a minimum amount of monitoring data I must obtain?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-control periods, or required monitoring system quality assurance or control activities in calculations... 40 Protection of Environment 6 2011-07-01 2011-07-01 false Is there a minimum amount of monitoring..., 2001 Monitoring § 60.2170 Is there a minimum amount of monitoring data I must obtain? (a) Except for...

  11. The one hundredth year of Rudolf Wolf's death: Do we have the correct reconstruction of solar activity?

    NASA Technical Reports Server (NTRS)

    Hoyt, Douglas V.; Schatten, Kenneth H.; Nesmes-Ribes, Elizabeth

    1994-01-01

    In the one hundred years since Wolf died, little effort has gone into research to see if improved reconstructions of sunspot numbers can be made. We have gathered more than 349,000 observations of daily sunspot group counts from more than 350 observers active from 1610 to 1993. Based upon group counts alone, it is possible to make an objective and homogeneous reconstruction of sunspot numbers. From our study, it appears that the Sun has steadily increased in activity since 1700 with the exception of a brief decrease in the Dalton Minimum (1795-1823). The significant results here are the greater depth of the Dalton Minimum, the generally lower activity throughout the 1700's, and the gradual rise in activity from the Maunder Minimum to the present day. This solar activity reconstruction is quite similar to those Wolf published before 1868 rather than the revised Wolf reconstructions after 1873 which used geomagnetic fluctuations.

  12. Solar activities and Climate change hazards

    NASA Astrophysics Data System (ADS)

    Hady, A. A., II

    2014-12-01

    Throughout the geological history of Earth, climate change is one of the recurrent natural hazards. In recent history, the impact of man brought about additional climatic change. Solar activities have had notable effect on palaeoclimatic changes. Contemporary, both solar activities and building-up of green-house gases effect added to the climatic changes. This paper discusses if the global worming caused by the green-house gases effect will be equal or less than the global cooling resulting from the solar activities. In this respect, we refer to the Modern Dalton Minimum (MDM) which stated that starting from year 2005 for the next 40 years; the earth's surface temperature will become cooler than nowadays. However the degree of cooling, previously mentioned in old Dalton Minimum (c. 210 y ago), will be minimized by building-up of green-house gases effect during MDM period. Regarding to the periodicities of solar activities, it is clear that now we have a new solar cycle of around 210 years. Keywords: Solar activities; solar cycles; palaeoclimatic changes; Global cooling; Modern Dalton Minimum.

  13. Characterizing operant hyperactivity in the Spontaneously Hypertensive Rat

    PubMed Central

    2012-01-01

    Background Operant hyperactivity, the emission of reinforced responses at an inordinately high rate, has been reported in children with ADHD and in the Spontaneously Hypertensive Rat (SHR), the most widely studied animal model of ADHD. The SHR emits behavior at hyperactive levels, relative to a normoactive strain, only when such behavior is seldom reinforced. Because of its dependence on rate of reinforcement, operant hyperactivity appears to be driven primarily by incentive motivation, not motoric capacity. This claim was evaluated in the present study using a novel strategy, based on the organization of behavior in bouts of reinforced responses separated by pauses. Method Male SHR, Wistar-Kyoto (WKY) and Wistar rats (WIS) were exposed each to a multiple variable-interval schedule of sucrose reinforcement (12, 24, 48, 96, and 192 s) between post-natal days (PND) 48 and 93. Responding in each schedule was examined in two epochs, PND 58-62 and 89-93. Parameters of response-reinforcement functions (Herrnstein's hyperbola) and bout-organized behavior were estimated in each epoch. Results SHR emitted higher response rates than WKY and WIS, but only when rate of reinforcement was low (fewer than 2 reinforcers per minute), and particularly in the second epoch. Estimates of Herrnstein's hyperbola parameters suggested the primacy of motivational over motoric factors driving the response-rate differential. Across epochs and schedules, a more detailed analysis of response bouts by SHR revealed that these were shorter than those by WKY, but more frequent than those by WKY and WIS. Differences in bout length subsided between epochs, but differences in bout-initiation rate were exacerbated. These results were interpreted in light of robust evidence linking changes in bout-organization parameters and experimental manipulations of motivation and response-reinforcement contingency. Conclusions Operant hyperactivity in SHR was confirmed. Although incentive motivation appears to play an important role in operant hyperactivity and motoric capacity cannot be ruled out as a factor, response-bout patterns suggest that operant hyperactivity is primarily driven by steeper delay-of-reinforcement gradients. Convergence of this conclusion with theoretical accounts of ADHD and with free-operant performance in children with ADHD supports the use of SHR as an animal model of ADHD. PMID:22277367

  14. Infant polysomnography: reliability and validity of infant arousal assessment.

    PubMed

    Crowell, David H; Kulp, Thomas D; Kapuniai, Linda E; Hunt, Carl E; Brooks, Lee J; Weese-Mayer, Debra E; Silvestri, Jean; Ward, Sally Davidson; Corwin, Michael; Tinsley, Larry; Peucker, Mark

    2002-10-01

    Infant arousal scoring based on the Atlas Task Force definition of transient EEG arousal was evaluated to determine (1). whether transient arousals can be identified and assessed reliably in infants and (2). whether arousal and no-arousal epochs scored previously by trained raters can be validated reliably by independent sleep experts. Phase I for inter- and intrarater reliability scoring was based on two datasets of sleep epochs selected randomly from nocturnal polysomnograms of healthy full-term, preterm, idiopathic apparent life-threatening event cases, and siblings of Sudden Infant Death Syndrome infants of 35 to 64 weeks postconceptional age. After training, test set 1 reliability was assessed and discrepancies identified. After retraining, test set 2 was scored by the same raters to determine interrater reliability. Later, three raters from the trained group rescored test set 2 to assess inter- and intrarater reliabilities. Interrater and intrarater reliability kappa's, with 95% confidence intervals, ranged from substantial to almost perfect levels of agreement. Interrater reliabilities for spontaneous arousals were initially moderate and then substantial. During the validation phase, 315 previously scored epochs were presented to four sleep experts to rate as containing arousal or no-arousal events. Interrater expert agreements were diverse and considered as noninterpretable. Concordance in sleep experts' agreements, based on identification of the previously sampled arousal and no-arousal epochs, was used as a secondary evaluative technique. Results showed agreement by two or more experts on 86% of the Collaborative Home Infant Monitoring Evaluation Study arousal scored events. Conversely, only 1% of the Collaborative Home Infant Monitoring Evaluation Study-scored no-arousal epochs were rated as an arousal. In summary, this study presents an empirically tested model with procedures and criteria for attaining improved reliability in transient EEG arousal assessments in infants using the modified Atlas Task Force standards. With training based on specific criteria, substantial inter- and intrarater agreement in identifying infant arousals was demonstrated. Corroborative validation results were too disparate for meaningful interpretation. Alternate evaluation based on concordance agreements supports reliance on infant EEG criteria for assessment. Results mandate additional confirmatory validation studies with specific training on infant EEG arousal assessment criteria.

  15. Solar activity as driver for the Dark Age Grand Solar Minimum

    NASA Astrophysics Data System (ADS)

    Neuhäuser, Ralph; Neuhäuser, Dagmar

    2017-04-01

    We will discuss the role of solar activity for the temperature variability from AD 550 to 840, roughly the last three centuries of the Dark Ages. This time range includes the so-called Dark Age Grand Solar Minimum, whose deep part is dated to about AD 650 to 700, which is seen in increased radiocarbon, but decreased aurora observations (and a lack of naked-eye sunspot sightings). We present historical reports on aurorae from all human cultures with written reports including East Asia, Near East (Arabia), and Europe. To classify such reports correctly, clear criteria are needed, which are also discussed. We compare our catalog of historical aurorae (and sunspots) as well as C-14 data, i.e. solar activity proxies, with temperature reconstructions (PAGES). After increased solar activity until around AD 600, we see a dearth of aurorae and increased radiocarbon production in particular in the second half of the 7th century, i.e. a typical Grand Solar Minimum. Then, after about AD 690 (the maximum in radiocarbon, the end of the Dark Age Grand Minimum), we see increased auroral activity, decreasing radiocarbon, and increasing temperature until about AD 775. At around AD 775, we see the well-known strong C-14 variability (solar activity drop), then immediately another dearth of aurorae plus high C-14, indicating another solar activity minimum. This is consistent with a temperature depression from about AD 775 on into the beginning of the 9th century. Very high solar activity is then seen in the first four decades with four aurora clusters and three simultaneous sunspot clusters, and low C-14, again also increasing temperature. The period of increasing solar activity marks the end of the so-called Dark Ages: While auroral activity increases since about AD 793, temperature starts to increase quite exactly at AD 800. We can reconstruct the Schwabe cycles with aurorae and C-14 data. In summary, we can see a clear correspondence of the variability of solar activity proxies and surface temperature reconstructions. This indicates that solar activity is an important climate driver.

  16. Detection of Water Vapor in the Thermal Spectrum of the Non-transiting Hot Jupiter Upsilon Andromedae b

    NASA Astrophysics Data System (ADS)

    Piskorz, Danielle; Benneke, Björn; Crockett, Nathan R.; Lockwood, Alexandra C.; Blake, Geoffrey A.; Barman, Travis S.; Bender, Chad F.; Carr, John S.; Johnson, John A.

    2017-08-01

    The Upsilon Andromedae system was the first multi-planet system discovered orbiting a main-sequence star. We describe the detection of water vapor in the atmosphere of the innermost non-transiting gas giant ups And b by treating the star-planet system as a spectroscopic binary with high-resolution, ground-based spectroscopy. We resolve the signal of the planet’s motion and break the mass-inclination degeneracy for this non-transiting planet via deep combined flux observations of the star and the planet. In total, seven epochs of Keck NIRSPEC L band observations, three epochs of Keck NIRSPEC short-wavelength K band observations, and three epochs of Keck NIRSPEC long wavelength K band observations of the ups And system were obtained. We perform a multi-epoch cross-correlation of the full data set with an atmospheric model. We measure the radial projection of the Keplerian velocity (K P = 55 ± 9 km s-1), true mass ({M}{{b}}={1.7}-0.24+0.33 M J), and orbital inclination (I b 24° ± 4°), and determine that the planet’s opacity structure is dominated by water vapor at the probed wavelengths. Dynamical simulations of the planets in the ups And system with these orbital elements for ups And b show that stable, long-term (100 Myr) orbital configurations exist. These measurements will inform future studies of the stability and evolution of the ups And system, as well as the atmospheric structure and composition of the hot Jupiter.

  17. Frequency, risk factors, and outcomes of central nervous system relapse in lymphoma patients treated with dose-adjusted EPOCH plus rituximab.

    PubMed

    Malecek, Mary-Kate; Petrich, Adam M; Rozell, Shaina; Chu, Benjamin; Trifilio, Steven; Galanina, Natalie; Maurer, Matthew; Farooq, Umar; Link, Brian K; Nowakowski, Grzegorz S; Nabhan, Chadi; Ayed, Ayed O

    2017-11-01

    Central nervous system (CNS) relapse in non-Hodgkin lymphoma (NHL) is a rare but serious complication that carries a poor prognosis. The use of infusional etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin, and rituximab (EPOCH-R) for frontline treatment of diffuse large B cell lymphoma (DLBCL) is increasing, though little is known about incidence of and risk factors for CNS relapse with this regimen PATIENTS AND METHODS: We completed a chart review of patients with NHL who received EPOCH-R as front line therapy. Data obtained included baseline and treatment characteristics including if patients received CNS directed therapy. We measured overall survival (OS), progression free survival (PFS), and progression to CNS involvement. We identified 223 patients who met the inclusion criteria, 72% had DLBCL. Of all the patients, 5.8% experienced CNS relapse, and 38.6% were treated with CNS prophylaxis. There was no difference in rate of CNS relapse, OS, or PFS between patients who had and had not received CNS prophylaxis. Patients whose serum lactate dehydrogenase was greater than twice the upper limit of normal at diagnosis and those with extranodal disease were significantly more likely to have CNS relapse (P = .0247 and 0.022, respectively) than their counterparts. The rate of CNS relapse in this patient population approaches 6%, not significantly different from reports on those receiving R-CHOP. The results of this study suggest that CNS prophylaxis might be more selectively used among patients treated with EPOCH-R with certain high-risk features. © 2017 Wiley Periodicals, Inc.

  18. Dissociation between dorsal and ventral hippocampal theta oscillations during decision-making.

    PubMed

    Schmidt, Brandy; Hinman, James R; Jacobson, Tara K; Szkudlarek, Emily; Argraves, Melissa; Escabí, Monty A; Markus, Etan J

    2013-04-03

    Hippocampal theta oscillations are postulated to support mnemonic processes in humans and rodents. Theta oscillations facilitate encoding and spatial navigation, but to date, it has been difficult to dissociate the effects of volitional movement from the cognitive demands of a task. Therefore, we examined whether volitional movement or cognitive demands exerted a greater modulating factor over theta oscillations during decision-making. Given the anatomical, electrophysiological, and functional dissociations along the dorsal-ventral axis, theta oscillations were simultaneously recorded in the dorsal and ventral hippocampus in rats trained to switch between place and motor-response strategies. Stark differences in theta characteristics were found between the dorsal and ventral hippocampus in frequency, power, and coherence. Theta power increased in the dorsal, but decreased in the ventral hippocampus, during the decision-making epoch. Interestingly, the relationship between running speed and theta power was uncoupled during the decision-making epoch, a phenomenon limited to the dorsal hippocampus. Theta frequency increased in both the dorsal and ventral hippocampus during the decision epoch, although this effect was greater in the dorsal hippocampus. Despite these differences, ventral hippocampal theta was responsive to the navigation task; theta frequency, power, and coherence were all affected by cognitive demands. Theta coherence increased within the dorsal hippocampus during the decision-making epoch on all three tasks. However, coherence selectively increased throughout the hippocampus (dorsal to ventral) on the task with new hippocampal learning. Interestingly, most results were consistent across tasks, regardless of hippocampal-dependent learning. These data indicate increased integration and cooperation throughout the hippocampus during information processing.

  19. Precision ephemerides for gravitational-wave searches. I. Sco X-1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Galloway, Duncan K.; Premachandra, Sammanani; Steeghs, Danny

    2014-01-20

    Rapidly rotating neutron stars are the only candidates for persistent high-frequency gravitational wave emission, for which a targeted search can be performed based on the spin period measured from electromagnetic (e.g., radio and X-ray) observations. The principal factor determining the sensitivity of such searches is the measurement precision of the physical parameters of the system. Neutron stars in X-ray binaries present additional computational demands for searches due to the uncertainty in the binary parameters. We present the results of a pilot study with the goal of improving the measurement precision of binary orbital parameters for candidate gravitational wave sources. Wemore » observed the optical counterpart of Sco X-1 in 2011 June with the William Herschel Telescope and also made use of Very Large Telescope observations in 2011 to provide an additional epoch of radial-velocity measurements to earlier measurements in 1999. From a circular orbit fit to the combined data set, we obtained an improvement of a factor of 2 in the orbital period precision and a factor of 2.5 in the epoch of inferior conjunction T {sub 0}. While the new orbital period is consistent with the previous value of Gottlieb et al., the new T {sub 0} (and the amplitude of variation of the Bowen line velocities) exhibited a significant shift, which we attribute to variations in the emission geometry with epoch. We propagate the uncertainties on these parameters through to the expected Advanced LIGO-Virgo detector network observation epochs and quantify the improvement obtained with additional optical observations.« less

  20. Multi-epoch monitoring of the AA Tauri-like star V 354 Mon. Indications for a low gas-to-dust ratio in the inner disk warp

    NASA Astrophysics Data System (ADS)

    Schneider, P. C.; Manara, C. F.; Facchini, S.; Günther, H. M.; Herczeg, G. J.; Fedele, D.; Teixeira, P. S.

    2018-06-01

    Disk warps around classical T Tauri stars (CTTSs) can periodically obscure the central star for some viewing geometries. For these so- called AA Tau-like variables, the obscuring material is located in the inner disk and absorption spectroscopy allows one to characterize its dust and gas content. Since the observed emission from CTTSs consists of several components (photospheric, accretion, jet, and disk emission), which can all vary with time, it is generally challenging to disentangling disk features from emission variability. Multi- epoch, flux-calibrated, broadband spectra provide us with the necessary information to cleanly separate absorption from emission variability. We applied this method to three epochs of VLT/X-shooter spectra of the CTTS V 354 Mon (CSI Mon-660) located in NGC 2264 and find that: (a) the accretion emission remains virtually unchanged between the three epochs; (b) the broadband flux evolution is best described by disk material obscuring part of the star, and (c) the Na and K gas absorption lines show only a minor increase in equivalent width during phases of high dust extinction. The limits on the absorbing gas column densities indicate a low gas-to-dust ratio in the inner disk, less than a tenth of the ISM value. We speculate that the evolutionary state of V 354 Mon, rather old with a low accretion rate, is responsible for the dust excess through an evolution toward a dust dominated disk or through the fragmentation of larger bodies that drifted inward from larger radii in a still gas dominated disk.

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