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Sample records for mis vib kujuneda

  1. MIS On-Line.

    ERIC Educational Resources Information Center

    Thomson, Nancy S.; Echeverria, Donna Rose; Mills, Bob

    This paper describes the resources, processes and outcomes involved in the development of an introductory Management Information Systems (MIS) course designed to utilize as many of the technologies as possible to redefine the teaching/learning paradigm. The MIS-Online project at Northwest Missouri State University encompasses the available campus…

  2. Orexin-dependent activation of layer VIb enhances cortical network activity and integration of non-specific thalamocortical inputs.

    PubMed

    Hay, Y Audrey; Andjelic, Sofija; Badr, Sammy; Lambolez, Bertrand

    2015-11-01

    Neocortical layer VI is critically involved in thalamocortical activity changes during the sleep/wake cycle. It receives dense projections from thalamic nuclei sensitive to the wake-promoting neuropeptides orexins, and its deepest part, layer VIb, is the only cortical lamina reactive to orexins. This convergence of wake-promoting inputs prompted us to investigate how layer VIb can modulate cortical arousal, using patch-clamp recordings and optogenetics in rat brain slices. We found that the majority of layer VIb neurons were excited by nicotinic agonists and orexin through the activation of nicotinic receptors containing α4-α5-β2 subunits and OX2 receptor, respectively. Specific effects of orexin on layer VIb neurons were potentiated by low nicotine concentrations and we used this paradigm to explore their intracortical projections. Co-application of nicotine and orexin increased the frequency of excitatory post-synaptic currents in the ipsilateral cortex, with maximal effect in infragranular layers and minimal effect in layer IV, as well as in the contralateral cortex. The ability of layer VIb to relay thalamocortical inputs was tested using photostimulation of channelrhodopsin-expressing fibers from the orexin-sensitive rhomboid nucleus in the parietal cortex. Photostimulation induced robust excitatory currents in layer VIa neurons that were not pre-synaptically modulated by orexin, but exhibited a delayed, orexin-dependent, component. Activation of layer VIb by orexin enhanced the reliability and spike-timing precision of layer VIa responses to rhomboid inputs. These results indicate that layer VIb acts as an orexin-gated excitatory feedforward loop that potentiates thalamocortical arousal.

  3. ALPHA MIS: Reference manual

    SciTech Connect

    Lovin, J.K.; Haese, R.L.; Heatherly, R.D.; Hughes, S.E.; Ishee, J.S.; Pratt, S.M.; Smith, D.W.

    1992-02-01

    ALPHA is a powerful and versatile management information system (MIS) initiated and sponsored and by the Finance and Business Management Division of Oak Ridge National Laboratory, who maintain and develop it in concert with the Business Systems Division for its Information Center. A general-purpose MIS, ALPHA allows users to access System 1022 and System 1032 databases to obtain and manage information. From a personal computer or a data terminal, Energy Systems employees can use ALPHA to control their own report reprocessing. Using four general commands (Database, Select, Sort, and Report) they can (1) choose a mainframe database, (2) define subsets within it, (3) sequentially order a subset by one or more variables, and (4) generate a report with their own or a canned format.

  4. MIS - The Human Connection

    PubMed Central

    Bush, Ian E.

    1980-01-01

    The lessons of the 70's with MIS were largely painful, often the same as those of the 60's, and were found in different phases on two continents. On examination this turns out to be true for many non-medical fields, true for systems programming, and thus a very general phenomenon. It is related to the functional complexity rather than to the sheer size of the software required, and above all to the relative neglect of human factors at all levels of software and hardware design. Simple hierarchical theory is a useful tool for analyzing complex systems and restoring the necessary dominance of common sense human factors. An example shows the very large effects of neglecting these factors on costs and benefits of MIS and their sub-systems.

  5. Re-evaluation of the 1962 Mark VI-B dynamic tests regarding reactivity coefficients

    SciTech Connect

    Burnett, T.

    1991-06-01

    The 1962 Mark VI-B rod tests have been re-evaluated. A significantly lower (more negative) coolant coefficient is now ascribed to that test, {minus}1 pcm/Deg-C vs the previously reported +2 pcm/Deg-C. The change from the previous value is because of revisions to delayed neutron constants and accounting for spatial effects. The new value is in reasonable agreement with the currently calculated value of {minus}2 pcm/Deg-C, considering measurement and calculational uncertainties. Therefore, the authors conclude that the current analytic models for physics and transient analysis methodology (GLASS, GRIMHX & TRIMHX, AND MARY) are fully consistent with 1962 test observations, and that there is no basis for assigning a calculational bias or increasing uncertainty allowances.

  6. Photocapacitive MIS infrared detectors

    NASA Technical Reports Server (NTRS)

    Sher, A.; Lu, S. S.-M.; Moriarty, J. A.; Crouch, R. K.; Miller, W. E.

    1978-01-01

    A new class of room-temperature infrared detectors has been developed through use of metal-insulator-semiconductor (MIS) or metal-insulator-semiconductor-insulator-metal (MISIM) slabs. The detectors, which have been fabricated from Si, Ge and GaAs, rely for operation on the electrical capacitance variations induced by modulated incident radiation. The peak detectivity for a 1000-A Si MISIM detector is comparable to that of a conventional Si detector functioning in the photovoltaic mode. Optimization of the photocapacitive-mode detection sensitivity is discussed.

  7. Carbide-forming groups IVB-VIB metals: a new territory in the periodic table for CVD growth of graphene.

    PubMed

    Zou, Zhiyu; Fu, Lei; Song, Xiuju; Zhang, Yanfeng; Liu, Zhongfan

    2014-07-09

    Early transition metals, especially groups IVB-VIB metals, can form stable carbides, which are known to exhibit excellent "noble-metal-like" catalytic activities. We demonstrate herein the applications of groups IVB-VIB metals in graphene growth using atmospheric pressure chemical vapor deposition technique. Similar to the extensively studied Cu, Ni, and noble metals, these transition-metal foils facilitate the catalytic growth of single- to few-layer graphene. The most attractive advantage over the existing catalysts is their perfect control of layer thickness and uniformity with highly flexible experimental conditions by in situ converting the dissolved carbons into stable carbides to fully suppress the upward segregation/precipitation effect. The growth performance of graphene on these transition metals can be well explained by the periodic physicochemical properties of elements. Our work has disclosed a new territory of catalysts in the periodic table for graphene growth and is expected to trigger more interest in graphene research.

  8. The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation.

    PubMed

    Robert, T; Nore, A; Brun, C; Maffre, C; Crimi, B; Bourbon, H-M; de Massy, B

    2016-02-26

    Meiotic recombination is induced by the formation of DNA double-strand breaks (DSBs) catalyzed by SPO11, the ortholog of subunit A of TopoVI DNA topoisomerase (TopoVIA). TopoVI activity requires the interaction between A and B subunits. We identified a conserved family of plant and animal proteins [the TOPOVIB-Like (TOPOVIBL) family] that share strong structural similarity to the TopoVIB subunit of TopoVI DNA topoisomerase. We further characterize the meiotic recombination proteins Rec102 (Saccharomyces cerevisiae), Rec6 (Schizosaccharomyces pombe), and MEI-P22 (Drosophila melanogaster) as homologs to the transducer domain of TopoVIB. We demonstrate that the mouse TOPOVIBL protein interacts and forms a complex with SPO11 and is required for meiotic DSB formation. We conclude that meiotic DSBs are catalyzed by a complex involving SPO11 and TOPOVIBL.

  9. [Project PEACH: A Prescriptive Educational Approach for Children with Handicaps. E.S.E.A. - Title VI-B. 1976-1977, and Appendix]. Report #77154.

    ERIC Educational Resources Information Center

    Scheiner, Louis

    The School District of Philadelphia, through its Prescriptive Educational Approach to Children with Handicaps (PEACH) Project, funded under E.S.E.A. Title VI-B, provided diagnostic, referral, and prescriptive educational services for preschool children (between 3 and 4.7 years). Priority was given to those children most severely handicapped and…

  10. Mis or sis solar cells

    SciTech Connect

    Rickus, E.; Jager, K.

    1985-01-22

    The function of the insulating film in MIS and SIS solar cells can also be fulfilled by a semiconductor with a sufficiently large energy gap. The doping of the quasi insulating layer guarantees good fill factors and short-circuit current densities also at a relatively high film thickness. For cadmium selenide solar cells with a quasi insulating film made of zinc selenide, copper is preferably used as a doping material.

  11. OsSpo11-4, a rice homologue of the archaeal TopVIA protein, mediates double-strand DNA cleavage and interacts with OsTopVIB.

    PubMed

    An, Xiao Jing; Deng, Zhu Yun; Wang, Tai

    2011-01-01

    DNA topoisomerase VI from Archaea, a heterotetrameric complex composed of two TopVIA and two TopVIB subunits, is involved in altering DNA topology during replication, transcription and chromosome segregation by catalyzing DNA strand transfer through transient double-strand breaks. The sequenced yeast and animal genomes encode only one homologue of the archaeal TopVIA subunit, namely Spo11, and no homologue of the archaeal TopVIB subunit. In yeast, Spo11 is essential for initiating meiotic recombination and this function appears conserved among other eukaryotes. In contrast to yeast and animals, studies in Arabidopsis and rice have identified three Spo11/TopVIA homologues and one TopVIB homologue in plants. Here, we further identified two novel Spo11/TopVIA homologues (named OsSpo11-4 and OsSpo11-5, respectively) that exist just in the monocot model plant Oryza sativa, indicating that at least five Spo11/TopVIA homologues are present in the rice genome. To reveal the biochemical function of the two novel Spo11/TopVIA homologues, we first examined the interactions among OsSpo11-1, OsSpo11-4, OsSpo11-5, and OsTopVIB by yeast two-hybrid assay. The results showed that OsSpo11-4 and OsTopVIB can self-interact strongly and among the 3 examined OsSpo11 proteins, only OsSpo11-4 interacted with OsTopVIB. Pull-down assay confirmed the interaction between OsSpo11-4 and OsTopVIB, which indicates that OsSpo11-4 may interact with OsTopVIB in vivo. Further in vitro enzymatic analysis revealed that among the above 4 proteins, only OsSpo11-4 exhibited double-strand DNA cleavage activity and its enzymatic activity appears dependent on Mg(2+) and independent of OsTopVIB, despite its interaction with OsTopVIB. We further analyzed the biological function of OsSpo11-4 by RNA interference and found that down-regulated expression of OsSpo11-4 led to defects in male meiosis, indicating OsSpo11-4 is required for meiosis.

  12. Model-based Characterization of the Parameters of Dissimilatory Sulfate Reduction Under the Effect of Different Initial Density of Desulfovibrio piger Vib-7 Bacterial Cells.

    PubMed

    Kushkevych, Ivan; Bolis, Marco; Bartos, Milan

    2015-01-01

    The objective of this study was to design a model of dissimilatory sulfate reduction process using the Verhulst function, with a particular focus on the kinetics of bacterial growth, sulfate and lactate consumption, and accumulation of hydrogen sulfide and acetate. The effect of the initial density (0.12±0.011, 0.25±0.024, 0.5±0.048 and 1.0±0.096 mg cells/ml of medium) of the sulfate-reducing bacteria Desulfovibrio piger Vib-7 on the growth and dissimilatory sulfate reduction was studied. The exponential growth phase of the D. piger Vib-7 was observed for 72 hours of cultivation at the (0.12 and 0.25 mg/ml) initial concentration of bacterial cells. Sulfate and lactate were consumed incompletely during this time. The increase in the initial concentration of cells to 0.5 and 1 mg/ml led to a shortening of the exponential bacterial growth phase and a shift to the stationary phase of the growth. In the case of 0.5 mg/ml seeding, the stationary growth phase was observed in the 36(th) hour of cultivation. The increase in the initial concentration of cells to 1 mg/ml led to the beginning of the stationary growth phase in 24th hours of cultivation. Under these conditions, sulfate and lactate were consumed completely in the 48th hour of cultivation. The kinetic analysis of the curves of bacterial growth and the process of dissimilatory sulfate reduction by D. piger Vib-7 was carried out.

  13. Developing a Management Information Systems (MIS) Curriculum: Perspectives from MIS Practitioners.

    ERIC Educational Resources Information Center

    Ehie, Ike C.

    2002-01-01

    A management information systems (MIS) curriculum was developed through review of existing programs and feedback from 24 MIS practitioners. Key aspects of the role of the information systems professional were identified: knowledge of integrated business processes, programming skills, and technical skills in niche areas. (Contains 17 references.)…

  14. Climate changes in south western Iberia and Mediterranean Outflow variations during two contrasting cycles of the last 1 Myrs: MIS 31-MIS 30 and MIS 12-MIS 11

    NASA Astrophysics Data System (ADS)

    Sánchez Goñi, M. F.; Llave, E.; Oliveira, D.; Naughton, F.; Desprat, S.; Ducassou, E.; Hodell, D. A.; Hernández-Molina, F. J.

    2016-01-01

    Grain size analysis and physical properties of Sites U1388, U1389 and U1390 collected in the Contourite Depositional System of the Gulf of Cádiz during the Integrated Ocean Drilling Program (IODP) Expedition 339 "Mediterranean Outflow" reveal relative changes in bottom current strength, a tracer of the dynamics of the Mediterranean Outflow Water (MOW), before and after the Middle Pleistocene Transition (MPT). The comparison of MOW behavior with climate changes identified by the pollen analysis and δ18O benthic foraminifera measurements of Site U1385, the Shackleton Site, collected in the south western Iberian margin shows that the interval MIS 31-MIS 30, ~ 1.1-1.05 million years ago (Ma), before the MPT, was marked by wetter climate and weaker bottom current than the interval MIS 12-MIS 11 (0.47-0.39 Ma), after the MPT. Similarly, the increase in fine particles from these glacials to interglacials and in coarse fraction from interglacials to glacials was coeval with forest and semi-desert expansions, respectively, indicating the lowering/enhancement of MOW strength during periods of regional increase/decrease of moisture. While these findings may not necessarily apply to all glacial/interglacial cycles, they nonetheless serve as excellent supporting examples of the hypothesis that aridification can serve as a good tracer for MOW intensity. The strongest regional aridity during MIS 12 coincides with a remarkable increase of coarse grain size deposition and distribution that we interpret as a maximum in MOW strength. This MOW intensification may have pre-conditioned the North Atlantic by increasing salinity, thereby triggering the strong resumption of the Meridional Overturning Circulation that could contribute to the great warmth that characterizes the MIS 11c super-interglacial.

  15. Differential binding partners of the Mis18α/β YIPPEE domains regulates the Mis18 complex recruitment to centromeres

    PubMed Central

    Knippler, Christina M.; Foltz, Daniel R.

    2016-01-01

    The Mis18 complex specifies the site of new CENP-A nucleosome assembly by recruiting the CENP-A specific assembly factor HJURP (Holliday junction recognition protein). The human Mis18 complex consists of Mis18α, Mis18β and Mis18 binding protein 1 (Mis18BP1/hsKNL2). Although Mis18α and Mis18β are highly homologous proteins, we find that their conserved YIPPEE domains mediate distinct interactions that are essential to link new CENP-A deposition to existing centromeres. We find that Mis18α directly interacts with the N-terminus of Mis18BP1; whereas, Mis18β directly interacts with CENP-C during G1 phase, revealing that these proteins have evolved to serve distinct functions in centromeres of higher eukaryotes. The N-terminus of Mis18BP1, containing both the Mis18α and CENP-C binding domains, is necessary and sufficient for centromeric localization. Therefore, the Mis18 complex contains dual CENP-C recognition motifs that are combinatorially required to generate robust centromeric localization that leads to CENP-A deposition. PMID:27239045

  16. Man in a Changing Society--MIS.

    ERIC Educational Resources Information Center

    Marklund, Inger, Ed.; Otter, Annica, Ed.

    1985-01-01

    Described is the Man in a Changing Society (MIS) project in which K-12 Swedish children use parish records to study and research local history. Church records in Sweden contain detailed information about individuals living during the 18th and 19th centuries. To make this information accessible to researchers, the Swedish church records are being…

  17. Incorporating Virtual Teamwork Training into MIS Curricula

    ERIC Educational Resources Information Center

    Chen, Fang; Sager, James; Corbitt, Gail; Gardiner, Stanley C.

    2008-01-01

    Due to increasing industry demand for personnel who work effectively in virtual/distributed teams, MIS students should undergo training to improve their awareness of and competence in virtual teamwork. This paper proposes a model for virtual teamwork training and describes the implementation of the model in a class where students were located in…

  18. Language, Violence, and Indian Mis-education.

    ERIC Educational Resources Information Center

    Russell, Caskey

    2002-01-01

    Traces the history of institutionalized violence--both physical and symbolic--within American Indian education; the legacy of shame and guilt from the boarding school era, when oppression was internalized; and the relationship of such "mis-education" to the decline of Tlingit language and culture in southwestern Alaska. Discusses…

  19. Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28.

    PubMed

    Smargon, Aaron A; Cox, David B T; Pyzocha, Neena K; Zheng, Kaijie; Slaymaker, Ian M; Gootenberg, Jonathan S; Abudayyeh, Omar A; Essletzbichler, Patrick; Shmakov, Sergey; Makarova, Kira S; Koonin, Eugene V; Zhang, Feng

    2017-02-16

    CRISPR-Cas adaptive immune systems defend microbes against foreign nucleic acids via RNA-guided endonucleases. Using a computational sequence database mining approach, we identify two class 2 CRISPR-Cas systems (subtype VI-B) that lack Cas1 and Cas2 and encompass a single large effector protein, Cas13b, along with one of two previously uncharacterized associated proteins, Csx27 and Csx28. We establish that these CRISPR-Cas systems can achieve RNA interference when heterologously expressed. Through a combination of biochemical and genetic experiments, we show that Cas13b processes its own CRISPR array with short and long direct repeats, cleaves target RNA, and exhibits collateral RNase activity. Using an E. coli essential gene screen, we demonstrate that Cas13b has a double-sided protospacer-flanking sequence and elucidate RNA secondary structure requirements for targeting. We also find that Csx27 represses, whereas Csx28 enhances, Cas13b-mediated RNA interference. Characterization of these CRISPR systems creates opportunities to develop tools to manipulate and monitor cellular transcripts.

  20. Integrating Intellectual Property Concepts into MIS Education: An Empirical Assessment

    ERIC Educational Resources Information Center

    Mykytyn, Peter P., Jr.; Mykytyn, Kathleen; Harrison, David A.

    2005-01-01

    The evolving legal environment surrounding intellectual property (IP) and its impact on information systems, especially involving electronic commerce, and the type of education and training provided by management information systems (MIS) faculty to MIS students is a relationship that has not been investigated. Although organizations are…

  1. Perceived Requirements of MIS Curriculum Implementation in Bilingual Developing Countries

    ERIC Educational Resources Information Center

    Kabeil, Magdy M.

    2005-01-01

    This paper addresses additional requirements associated with implementing a standard curriculum of Management Information Systems (MIS) in bilingual developing countries where both students and workplace users speak English as a second language. In such countries, MIS graduates are required to develop bilingual computer applications and to…

  2. Mice deficient in Group VIB phospholipase A2 (iPLA2γ) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet

    PubMed Central

    Song, Haowei; Wohltmann, Mary; Bao, Shunzhong; Ladenson, Jack H.; Semenkovich, Clay F.

    2010-01-01

    Phospholipases A2 (PLA2) play important roles in metabolic processes, and the Group VI PLA2 family is comprised of intracellular enzymes that do not require Ca2+ for catalysis. Mice deficient in Group VIA PLA2 (iPLA2β) develop more severe glucose intolerance than wild-type (WT) mice in response to dietary stress. Group VIB PLA2 (iPLA2γ) is a related enzyme distributed in membranous organelles, including mitochondria, and iPLA2γ knockout (KO) mice exhibit altered mitochondrial morphology and function. We have compared metabolic responses of iPLA2γ-KO and WT mice fed a Western diet (WD) with a high fat content. We find that KO mice are resistant to WD-induced increases in body weight and adiposity and in blood levels of cholesterol, glucose, and insulin, even though WT and KO mice exhibit similar food consumption and dietary fat digestion and absorption. KO mice are also relatively resistant to WD-induced insulin resistance, glucose intolerance, and altered patterns of fat vs. carbohydrate fuel utilization. KO skeletal muscle exhibits impaired mitochondrial β-oxidation of fatty acids, as reflected by accumulation of larger amounts of long-chain acylcarnitine (LCAC) species in KO muscle and liver compared with WT in response to WD feeding. This is associated with increased urinary excretion of LCAC and much reduced deposition of triacylglycerols in liver by WD-fed KO compared with WT mice. The iPLA2γ-deficient genotype thus results in a phenotype characterized by impaired mitochondrial oxidation of fatty acids and relative resistance to the metabolic abnormalities induced by WD. PMID:20179248

  3. Water sorption mechanisms for MIS materials.

    SciTech Connect

    Veirs, D. K.; Mason, R. E.; Erickson, R. M.

    2002-01-01

    The fundamental processes that control the amount of water sorbed by impure plutonium-containing materials after calcination are reviewed. Of particular interest is the amount of and rate of moisture sorption at 1000 PPMv (parts-per-million vapor; -3% RH at 25 'C) and 10,000 PPMv (32% RH at 25 'C). Pure plutonium oxide powders will remain below the 0.5 wt% criterion for packaging in the DOE 3013 Standard at both water vapor concentrations [I]. Deliquescent salts that have been observed in calcined materials by DOES Materials Identification and Surveillance (MIS) program will exceed the 0.5 wt% criterion at 10,000 PPMv and will meet that standard at 1,000 PPMv. Hydrated salts will exceed the 0.5 wt% criterion at all technologically achievable water vapor concentrations if allowed to reach equilibrium. Controlling the moisture availability by controlling the atmospheric content at 1000 PPM' and limiting the access to atmospheric moisture after stabilization through the use of a properly configured stabilization boat will minimize moisture uptake by these materials.

  4. Mis-Spliced Lr34 Transcript Events in Winter Wheat

    PubMed Central

    Fang, Tilin; Carver, Brett F.; Hunger, Robert M.; Yan, Liuling

    2017-01-01

    Lr34 in wheat is a non-race-specific gene that confers resistance against multiple fungal pathogens. The resistant allele Lr34 and the susceptible allele Lr34s can be distinguished by three polymorphisms that cause alternation of deduced amino acid sequences of Lr34 at the protein level. In seedlings of a cultivar carrying the resistant Lr34r allele, only a portion (35%) of its transcripts was correctly spliced and the majority (65%) of its transcripts were incorrectly spliced due to multiple mis-splicing events. Lr34 mis-splicing events were also observed at adult plant age when this gene exerts its function. All of the mis-spliced Lr34r cDNA transcripts observed in this study resulted in a premature stop codon due to a shift of the open reading frame; hence, the mis-spliced Lr34r cDNAs were deduced to encode incomplete proteins. Even if a cultivar has a functional Lr34 gene, its transcripts might not completely splice in a correct pattern. These findings suggested that the partial resistance conferred by a quantitative gene might be due to mis-splicing events in its transcripts; hence, the resistance of the gene could be increased by eliminating or mutating regulators that cause mis-splicing events in wheat. PMID:28135317

  5. Modelling the warm interglacials: analogues of MIS1

    NASA Astrophysics Data System (ADS)

    Herold, N.; Yin, Q. Z.; Karami, M. P.; Berger, A.

    2012-04-01

    Determining interglacial diversity, primarily as a function of duration, intensity and unique climate responses to Earth's orbital variations has become a focal point for researchers trying to better understand our current interglacial. Numerous interglacials have been espoused as Marine Isotopic Stage (MIS) 1 analogues or windows into the future of Holocene climate based on their astronomical characteristics, seasonal insolation patterns or their similarity with predicted anthropogenic warming. However, to date there has been little quantitative study of the climate of these interglacials within a physically robust framework. Here we examine the climate response to peak interglacial forcing during MIS1, 5, 9, 11 and 19 using the Community Climate System Model 3. We determine which interglacial provides the closest analogue to peak MIS1 conditions as well as the mechanisms which dominate the surface climate responses of these interglacials. Considering the differences in astronomical parameters and greenhouse gases we discount MIS5 and 9 as analogues to peak MIS1 conditions due to their significant warmth and stronger precipitation and vegetation responses. Conversely, based on seasonal and hemispheric averages of surface temperature, precipitation and sea-ice cover, MIS11 and 19 are most similar to MIS1, with MIS11 actually exhibiting a higher affinity particularly during boreal summer. This is attributed to a greater similarity in the seasonal and latitudinal distribution of insolation over middle latitude Eurasia and North America, which are the regions most sensitive to insolation change given the absence of ice-sheet dynamics in our model. Global ocean overturning circulation during MIS11 is also closer to MIS1 than circulation during MIS19 is, due predominantly to differences in Weddell Sea bottom water formation. Thus, under the assumption of present-day ice-sheets MIS11 appears to be the better climatic analogue to peak MIS1 conditions. In addition to the

  6. Quantitative reconstruction of precipitation and runoff during MIS 5a, MIS 3a, and Holocene, arid China

    NASA Astrophysics Data System (ADS)

    Liu, Yuan; Li, Yu

    2016-09-01

    Marine oxygen isotope stage 5a (MIS 5a), MIS 3a, and Holocene were highlighted periods in paleoclimate studies. Many scientists have published a great number of studies in this regard, but they paid more attention to qualitative research, and there was often a lack of quantitative data. In this paper, based on chronological evidence from a paleolake in arid China, MIS 5a, MIS 3a, and Holocene lake area, the precipitation of the drainage area and the runoff of the inflowing rivers of the lake were reconstructed with ArcGIS spatial analysis software and the improved water and energy balance model which was calibrated by modern meteorological and hydrological data in the Shiyang River drainage basin. The results showed that the paleolake areas were 1824, 1124, and 628 km2 for MIS 5a, MIS 3a, and Holocene; meanwhile, the paleoprecipitation and runoff were 293.992-297.433, 271.105-274.294, and 249.431-252.373 mm and 29.103 × 108-29.496 × 108, 18.810 × 108-18.959 × 108, and 10.637 × 108-10.777 × 108 mm, respectively. The quantitative data can help us not only strengthen the understanding of paleoclimatic characteristics but also recognize the complexity and diversity of the climate system.

  7. Persistent climatic and oceanographic oscillations in the subpolar North Atlantic during the MIS 6 glaciation and MIS 5 interglacial

    NASA Astrophysics Data System (ADS)

    Mokeddem, Zohra; McManus, Jerry F.

    2016-06-01

    Rapidly accumulating sediments from the Björn drift deposit south of Iceland are studied for comparison of glacial/interglacial climate changes related to millennial variability of the subpolar surface and deep ocean circulation in the North Atlantic. High-resolution faunal, isotopic, and sedimentary analyses reveal a strong multimillennial climatic variability interpreted as oscillations in heat transport westward south of Iceland during marine isotope stage 6 (MIS 6), possibly related to the strength of the subpolar gyre (SPG). The oscillations persisted from MIS 6 through the following interglacial (MIS 5), although with diminished magnitude, and were respectively characterized by repeated advances of the polar front south of Iceland during MIS 6 and southward migrations of the Arctic front due to cold surface outflow through the East Greenland and East Iceland Currents during MIS 5. Incursions of cold, fresh surface waters, and drifting ice affected the dynamics of the SPG, episodically causing it to weaken and contract to the northwest. During these intervals of diminished SPG, the northward transport of subtropical heat and salt was strengthened and preferentially conveyed to the northeast past Iceland, enhancing deep-water formation in the Nordic Seas. By contrast, when the SPG was strong, more subtropical water and its associated heat were entrained within the relatively warm Irminger Current flowing westward south of Iceland. These oceanographic oscillations were associated with repeated multimillennial cooling and warming episodes during the glacial stage MIS 6, equivalent to the Dansgaard-Oeschger cycles of the last glaciation.

  8. MIS capacitor studies on silicon carbide single crystals

    NASA Technical Reports Server (NTRS)

    Kopanski, J. J.

    1990-01-01

    Cubic SIC metal-insulator-semiconductor (MIS) capacitors with thermally grown or chemical-vapor-deposited (CVD) insulators were characterized by capacitance-voltage (C-V), conductance-voltage (G-V), and current-voltage (I-V) measurements. The purpose of these measurements was to determine the four charge densities commonly present in an MIS capacitor (oxide fixed charge, N(f); interface trap level density, D(it); oxide trapped charge, N(ot); and mobile ionic charge, N(m)) and to determine the stability of the device properties with electric-field stress and temperature. The section headings in the report include the following: Capacitance-voltage and conductance-voltage measurements; Current-voltage measurements; Deep-level transient spectroscopy; and Conclusions (Electrical characteristics of SiC MIS capacitors).

  9. Further study of inversion layer MIS solar cells

    NASA Technical Reports Server (NTRS)

    Ho, Fat Duen

    1992-01-01

    Many inversion layer metal-insulator-semiconductor (IL/MIS) solar cells have been fabricated. As of today, the best cell fabricated by us has a 9.138 percent AMO efficiency, with FF = 0.641, V(sub OC) = 0.557 V, and I(sub SC) = 26.9 micro A. Efforts made for fabricating an IL/MOS solar cell with reasonable efficiencies are reported. The more accurate control of the thickness of the thin layer of oxide between aluminum and silicon of the MIS contacts has been achieved by using two different process methods. Comparison of these two different thin oxide processings is reported. The effects of annealing time of the sample are discussed. The range of the resistivity of the substrates used in the IL cell fabrication is experimentally estimated. Theoretical study of the MIS contacts under dark conditions is addressed.

  10. A high-resolution mid-Pleistocene temperature record from Arctic Lake El'gygytgyn: a 50 kyr super interglacial from MIS 33 to MIS 31?

    NASA Astrophysics Data System (ADS)

    de Wet, Gregory A.; Castañeda, Isla S.; DeConto, Robert M.; Brigham-Grette, Julie

    2016-02-01

    Previous periods of extreme warmth in Earth's history are of great interest in light of current and predicted anthropogenic warming. Numerous so called ;super interglacial; intervals, with summer temperatures significantly warmer than today, have been identified in the 3.6 million year (Ma) sediment record from Lake El'gygytgyn, northeast Russia. To date, however, a high-resolution paleotemperature reconstruction from any of these super interglacials is lacking. Here we present a paleotemperature reconstruction based on branched glycerol dialkyl glycerol tetraethers (brGDGTs) from Marine Isotope Stages (MIS) 35 to MIS 29, including super interglacial MIS 31. To investigate this period in detail, samples were analyzed with an unprecedented average sample resolution of 500 yrs from MIS 33 to MIS 30. Our results suggest the entire period currently defined as MIS 33-31 (∼1114-1062 kyr BP) was characterized by generally warm and highly variable conditions at the lake, at times out of phase with Northern Hemisphere summer insolation, and that cold ;glacial; conditions during MIS 32 lasted only a few thousand years. Close similarities are seen with coeval records from high southern latitudes, supporting the suggestion that the interval from MIS 33 to MIS 31 was an exceptionally long interglacial (Teitler et al., 2015). Based on brGDGT temperatures from Lake El'gygytgyn (this study and unpublished results), warming in the western Arctic during MIS 31 was matched only by MIS 11 during the Pleistocene.

  11. A Perspective on a Management Information Systems (MIS) Program Review

    ERIC Educational Resources Information Center

    Yew, Bee K.

    2008-01-01

    This paper highlights relevant curriculum issues that were identified in a Management Information Systems (MIS) program review undertaken by a group of business faculty in a small regional university. The program review was initiated to improve job marketability of graduates and student enrollment. The review process is described as a collective…

  12. The Graduate MIS Security Course: Objectives and Challenges

    ERIC Educational Resources Information Center

    Jensen, Bradley K.; Guynes, Carl S.; Nyaboga, Andrew

    2009-01-01

    Given the magnitude of real and potential losses, both private and public employers increasingly expect graduates of management information systems (MIS) programs to understand information security concepts. The infrastructure requirements for the course includes setting up a secure laboratory environment to accommodate the development of viruses…

  13. Bio-inspired fluidic lens surgical camera for MIS.

    PubMed

    Tsai, Frank S; Johnson, Daniel; Cho, Sung Hwan; Qiao, Wen; Arianpour, Ashkan; Lo, Yu-Hwa

    2009-01-01

    We report a new type of surgical camera that will greatly improve minimally invasive surgery (MIS). The key enabling technology for this camera is a unique type of lens-bio-inspired fluidic lens, which is a bio-mimetic lens that can change its curvature, just like the way human crystalline lens can accommodate. Because of its curvature changing capability, it is now possible to design a new regime of optical systems where auto-focusing and optical zoom can be performed without moving the lens positions, as is done in typical cameras. Hence, miniaturized imaging system with high functionality can be achieved with such technology. MIS is a surgical technique where small incisions are made on the abdominal wall as opposed to a large cut in open surgery. This type of surgery ensures faster patient recovery. The key tool for MIS is its surgical camera, or laparoscope. Traditional laparoscope is long and rigid and limits the field of view. To further advance MIS technology, we utilized bio-inspired fluidic lens to design a highly versatile imager that is small, can change its field of view or zoom optically, works in low light conditions, and varies the viewing angles. The surgical camera prototype is small (total track<17 mm), possesses 3X optical zoom, operates with light emitting diode (LED) lighting, among many other unique features.

  14. Tau mis-splicing in the pathogenesis of neurodegenerative disorders

    PubMed Central

    Park, Sun Ah; Ahn, Sang Il; Gallo, Jean-Marc

    2016-01-01

    Tau proteins, which stabilize the structure and regulate the dynamics of microtubules, also play important roles in axonal transport and signal transduction. Tau proteins are missorted, aggregated, and found as tau inclusions under many pathological conditions associated with neurodegenerative disorders, which are collectively known as tauopathies. In the adult human brain, tau protein can be expressed in six isoforms due to alternative splicing. The aberrant splicing of tau pre-mRNA has been consistently identified in a variety of tauopathies but is not restricted to these types of disorders as it is also present in patients with non-tau proteinopathies and RNAopathies. Tau mis-splicing results in isoform-specific impairments in normal physiological function and enhanced recruitment of excessive tau isoforms into the pathological process. A variety of factors are involved in the complex set of mechanisms underlying tau mis-splicing, but variation in the cis-element, methylation of the MAPT gene, genetic polymorphisms, the quantity and activity of spliceosomal proteins, and the patency of other RNA-binding proteins, are related to aberrant splicing. Currently, there is a lack of appropriate therapeutic strategies aimed at correcting the tau mis-splicing process in patients with neurodegenerative disorders. Thus, a more comprehensive understanding of the relationship between tau mis-splicing and neurodegenerative disorders will aid in the development of efficient therapeutic strategies for patients with a tauopathy or other, related neurodegenerative disorders. [BMB Reports 2016; 49(8): 405-413] PMID:27222125

  15. Organizing for Effective Training Support in an MIS Environment.

    ERIC Educational Resources Information Center

    Hoffman, Stanford E.

    1994-01-01

    Describes how a management information system (MIS) at NASA (National Aeronautics and Space Administration) was adapted to ensure adequate training to accompany the development of computer applications. Highlights include semantic differences; user needs; time and budget constraints; and problems between users and programmers, including examples.…

  16. Validation and Analysis of a Multi-site MIS Prospective Registry Through Sub-analysis of an MIS TLIF Subgroup

    PubMed Central

    Raiszadeh, Kamshad; Raiszadeh, Ramin; Kim, Paul; Doerr, Todd; Siddiqi, Farhan; LaMotta, Ivan; Park, Paul; Templin, Cary; Gill, Sandeep; Liang, Kevin; Kim, Choll W.

    2014-01-01

    Study Design Retrospective analysis of multi-site, prospectively collected database. Objective To assess the validity and utility of a prospective spine registry by sub-analysis of patients treated with MIS TLIF. Background The MIS registry is a large-scale, multi-center series of prospectively collected clinical information on outcomes, complications, and adverse events for minimally invasive spine procedures for the treatment of degenerative lumbar conditions. Methods Analysis was performed on the MIS Prospective Registry database. A subgroup of patients treated by MIS TLIF technique was identified. Statistical analyses were performed on pre and post-operative data collected using validated health related quality of life outcome tools. Missing 1-year patient follow-up data was obtained through progressive correspondence modalities. Results Data analysis was performed on 98 MIS TLIF patients (56 female, 42 male) with a median age of 64.5 years (range 25-91 years) which were extracted from a total registry population of 478 patients. The one year follow-up rate was 87%. A total of 64 single-level, 23 two-level, 3 three-level, and 3 combined TLIFs staged with an MIS lateral procedure were included. The primary surgical indications were spondylolisthesis (27%), central stenosis (25%), foraminal stenosis (14%), post-laminectomy syndrome (14%) and degenerative scoliosis (6%). The peri-operative blood transfusion rate was 3%. Complications included intraoperative dural tear (n = 3), deep wound infection (n = 2), superficial dehiscence/cellulitis (n = 2). There was a 4% re-operation rate at the 1 year post-operative time point. Half of patients were discharged within 2 days (range 1-11 days, mean 2.97 days, median 2 days). All patients that were discharged on the first post-operative day (n = 14) underwent a single-level MIS TLIF procedure and had significantly lower pre-op disability index score than those discharged on POD 3-5 (43.7 ± 15.5 vs. 56.0 ± 18.3, p = 0

  17. Lake level fluctuations and catchment dynamics at Lake Ohrid (Macedonia, Albania) during MIS6 and MIS5

    NASA Astrophysics Data System (ADS)

    Francke, Alexander; Wagner, Bernd; Just, Janna; Sadori, Laura; Masi, Alessia; Vogel, Hendrik; Lindhorst, Katja; Krastel, Sebastian; Dosseto, Anthony; Rothacker, Leo; Leicher, Niklas; Gromig, Raphael

    2016-04-01

    Lake Ohrid, presumably the oldest lake of Europe located at the border of Macedonia and Albania, is about 30 km long, 15 km wide, and up to 290 m deep. In 2013, an ICDP deep drilling campaign was carried out under the umbrella of the Scientific Collaboration on Past Speciation Conditions in Lake Ohrid (SCOPSCO) project. At the main drill site (DEEP) in the central part of Lake Ohrid, the uppermost 568 m from a total sediment fill of ca. 700 m were recovered. Initial data from core catcher material indicate that the sediment sequence covers more than 1.2 million years. An age model, which is based on 11 tephrostratigragphic tie points and on tuning of biogeochemical proxy data versus orbital parameters reveals that that the upper 247 m of the DEEP site sequence cover the time period between 637 ka (MIS16) and the present. Inhere, we present sedimentological, (bio-)geochemical, environmental magnetic, and pollen data for the time period between MIS6 (191 ka) and MIS5 (71 ka). The data imply that MIS6 was one of the most severe glacial periods, while MIS5 was likely one of the more pronounced interglacial during the past 637 kyrs. The repercussions of these high amplitude climatic and environmental variations during this period are recorded in the sedimentological archive of Lake Ohrid. Previous studies based on hydro-acoustic and sediment core data from the northeastern part of the lake basin have shown that the lake level of Lake Ohrid was likely 60 m lower during MIS6. The ˜60 m lower lake level at Lake Ohrid during MIS6 can at least partly be explained by the ongoing subsidence, which persists in the basin until today. However, in the DEEP site sediments, the MIS6/MIS5 transition occurs at ca. 50 m sediment depth. This implies that climate-induced lake level fluctuation at Lake Ohrid are less severe compared for example to Lake Van (Turkey), were a 260 m lower lake level has been reported for the Younger Dryas. The imprint of the environmental variations between

  18. Electrical studies on cubic boron nitride MIS structures

    NASA Astrophysics Data System (ADS)

    Daniel, Abishai

    A systematic investigation of the electrical properties of Metal-cBN-p-Silicon MIS structures through Capacitance-Voltage and Leakage Current measurements was undertaken. Electrical leakage measurements were performed using an HP4145B Semiconductor Parameter Analyzer and Capacitance-Voltage results were obtained using an LCZ Meter. Poole-Frenkel conduction was observed to be dominant in cBN MIS structures at low electric fields. Trap height values obtained for the films were ˜0.8 eV. Schottky conduction was observed to be the dominant conduction in predominantly cBN MIS structures. The gold-cBN barrier height was obtained to be ˜0.6 eV. For a fraction of MIS structures incorporating indium gate metal, Poole-Frenkel and Schottky conduction was observed. For other contacts evidence was observed of the alloying of indium with cBN resulting in Ohmic-like behavior analogous to the behavior of indium with GaAs. Evidence of the pinning of the Fermi level at the Metal-Insulator interface was obtained from the similarity of the gold-cBN and indium-cBN barrier heights. MIS structures incorporating tBN as the insulating layer exhibited similar conduction behavior to the cBN MIS structures. The gold-tBN barrier height obtained was ˜0.68 eV and the trap height obtained was ˜0.86 eV. A correlation between leakage current and RMS roughness of the surface was observed providing evidence of roughness mediated field enhancement at the metal insulator interface resulting in higher leakage currents. Leakage current of the cBN MIS structures at high electric fields exhibit a similar functional relationship to post Soft Breakdown I-V curves of ultrathin oxides at high electric fields. Hard Breakdown was not observed for our films at fields up to 2 MV/cm. This sets a lower bound for the breakdown field for our BN films. Resistivity values in the range 109 O-cm to 1012 O-cm were obtained for cBN and tBN films. To our knowledge, we obtained the first Capacitance-Voltage results on BN

  19. The Changing Role of the MIS Professional: From Project Leader to Project Coordinator.

    ERIC Educational Resources Information Center

    Paxton, David J.; Lieberman, Norman J.

    1980-01-01

    Shifts in the content and context of the MIS professional's role at Hahnemann Medical College and Hospital, and the resulting impact on system projects are explored. Benefits include user responsibility and increased participation, MIS as a key to user learning system capabilities and limitations, and formation of a MIS-user team. (MLW)

  20. 32 CFR 22.325 - Historically Black colleges and universities (HBCUs) and other minority institutions (MIs).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Historically Black colleges and universities (HBCUs) and other minority institutions (MIs). 22.325 Section 22.325 National Defense Department of... other minority institutions (MIs). Increasing the ability of HBCUs and MIs to participate in...

  1. 32 CFR 22.325 - Historically Black colleges and universities (HBCUs) and other minority institutions (MIs).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Historically Black colleges and universities (HBCUs) and other minority institutions (MIs). 22.325 Section 22.325 National Defense Department of... other minority institutions (MIs). Increasing the ability of HBCUs and MIs to participate in...

  2. 32 CFR 22.325 - Historically Black colleges and universities (HBCUs) and other minority institutions (MIs).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Historically Black colleges and universities (HBCUs) and other minority institutions (MIs). 22.325 Section 22.325 National Defense Department of... other minority institutions (MIs). Increasing the ability of HBCUs and MIs to participate in...

  3. 32 CFR 22.325 - Historically Black colleges and universities (HBCUs) and other minority institutions (MIs).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Historically Black colleges and universities (HBCUs) and other minority institutions (MIs). 22.325 Section 22.325 National Defense Department of... other minority institutions (MIs). Increasing the ability of HBCUs and MIs to participate in...

  4. 32 CFR 22.325 - Historically Black colleges and universities (HBCUs) and other minority institutions (MIs).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Historically Black colleges and universities (HBCUs) and other minority institutions (MIs). 22.325 Section 22.325 National Defense Department of... other minority institutions (MIs). Increasing the ability of HBCUs and MIs to participate in...

  5. M-I-S solar cell - Theory and experimental results

    NASA Technical Reports Server (NTRS)

    Childs, R.; Fortuna, J.; Geneczko, J.; Fonash, S. J.

    1976-01-01

    The paper presents an operating-mode analysis of an MIS solar cell and discusses the advantages which can arise as a result of the use of transport control, field shaping (increased n factor), and zero bias barrier height modification. It is noted that for an n-type semiconductor, it is relatively easy to obtain an enhanced n factor using acceptor-like states without an increase in diode saturation current, the converse being true for p-type semiconductors. Several MIS configurations are examined: an acceptor-like, localized state configuration producing field shaping and no change in diode saturation current, and acceptor-like localized configurations producing field shaping, with a decrease of diode saturation current, in one case, and an increase in the other.

  6. High-Resolution Dust record of last glacial period (MIS 4 to MIS 2) from Talos Dome Ice Core

    NASA Astrophysics Data System (ADS)

    Mazzola, Claudia; Maggi, Valter; Delmonte, Barbara; Marino, Federica; Albani, Samuel

    2010-05-01

    Mineral dust trapped in Antarctic ice cores plays an important role in the study of past climate and atmospheric circulation variability in the Southern Hemisphere. In this work we investigate the Talos Dome (Northern Victoria Land, East Antarctica) ice core dust concentration record through a Laser Sensor (LS) technique. Analyses were performed in continuous as a part of the Continuous Flow Analysis (CFA) system, and discontinuously with Beckman Coulter©Counter for comparison and LS calibration. The LS device provided two basic outputs: (1) "bag" (1 m long sections) mean values and (2) high resolution (1 cm resolution) data. Both signals were processed in the contest of this work and two dust records, respectively at low and high resolution, were produced. Here we report the bag mean dust record from the end of the last deglaciation (about 12,000 years B.P.) to Marine Isotopic Stage 4 (MIS 4, 70,000 years BP). The comparison of the TALDICE LS and EPICA-Dome C dust record provides interesting information about climatic conditions of South Pacific-Ross Sea sector of Antarctica, and atmospheric circulation patterns during last glacial period, with a good agreement between MIS 3 and Last Glacial Maximum (LGM), where several millennial and plurimillennial scale climatic oscillation are observed. For these reasons it is possible suppose that dust transport mechanisms towards TD and DC were the same during the last glacial period. However, MIS 4 in TD ice core was lower, both in concentration and flux, compared to EDC. Likely, during LGM, very cool air masses extended above the Antarctic plateau, even in TD area, have created a subsidence condition which haven't allowed the cyclonic perturbation to penetrate the interior of Antarctica continent. In fact, the Polar Front has moved towards lower latitude in that period, maintaining far away the disturbances. These preliminary observations suggest that the coupling between inner sites such as EDC and the Talos Dome

  7. MIS 3 to MIS 1 temporal and LGM spatial variability in Arctic Ocean sea ice cover: Reconstruction from biomarkers

    NASA Astrophysics Data System (ADS)

    Xiao, Xiaotong; Stein, Ruediger; Fahl, Kirsten

    2015-07-01

    Using the sea ice proxy IP25 and phytoplankton-derived biomarkers (brassicasterol and dinosterol), Arctic sea ice conditions were reconstructed for Marine Isotope Stage (MIS) 3 to 1—with special emphasis on the Last Glacial Maximum (LGM)—in sediment cores from the northern Barents Sea continental margin across the central Arctic Ocean to the southern Mendeleev Ridge. Our results suggest more extensive sea ice cover than present day during the latter part of MIS 3, increasing sea ice growth during MIS 2 and decreased sea ice cover during the last deglacial. The summer ice edge remained north of the Barents Sea even during extremely cold (i.e., Last Glacial Maximum (LGM)) as well as warm periods (i.e., Bølling-Allerød). During the LGM, the western Svalbard margin and the northern Barents Sea margin areas were characterized by high concentrations of both IP25 and phytoplankton biomarkers, interpreted as a productive ice edge situation caused by the inflow of warm Atlantic water. In contrast, the LGM central Arctic Ocean (north of 84°N) was covered by thick permanent sea ice throughout the year with rare breakup, indicated by zero or near-zero biomarker concentrations. The spring/summer sea ice margin significantly extended southward to the Laptev Sea shelf (southern Lomonosov Ridge) and southern Mendeleev Ridge during the LGM. Our proxy reconstructions are very consistent with published model results based on the North Atlantic/Arctic Ocean Sea Ice Model.

  8. A MIS 15-MIS 12 record of environmental changes and Lower Palaeolithic occupation from Valle Giumentina, central Italy

    NASA Astrophysics Data System (ADS)

    Villa, Valentina; Pereira, Alison; Chaussé, Christine; Nomade, Sébastien; Giaccio, Biagio; Limondin-Lozouet, Nicole; Fusco, Fabio; Regattieri, Eleonora; Degeai, Jean-Philippe; Robert, Vincent; Kuzucuoglu, Catherine; Boschian, Giovanni; Agostini, Silvano; Aureli, Daniele; Pagli, Marina; Bahain, Jean Jacques; Nicoud, Elisa

    2016-11-01

    An integrated geological study, including sedimentology, stable isotope analysis (δ18O, δ13C), geochemistry, micromorphology, biomarker analysis, 40Ar/39Ar geochronology and tephrochronology, was undertaken on the Quaternary infill of the Valle Giumentina basin in Central Italy, which also includes an outstanding archaeological succession, composed of nine human occupation levels ascribed to the Lower and Middle Palaeolithic. 40Ar/39Ar dating, and other palaeoenvironmental and tephrochronological data, constrain the sedimentary history of the whole succession to the MIS 15-MIS 12 interval, between 618 ± 13 ka and 456 ± 2 ka. Palaeoenvironmental proxies suggest that over this time interval of about 150 ka, sedimentary and pedogenic processes were mainly influenced by climatic changes, in particular by the pulsing of local mountain glaciers of the Majella massif. Specifically, the Valle Giumentina succession records glacio-fluvial and lacustrine sedimentation during the colder glacial periods and pedogenesis and/or alluvial sedimentation during the warmer interglacial and/or interstadial periods. During this interval, tectonics played a negligible role as a driving factor of local morphogenesis and sedimentation, whereas the general regional uplift experienced in the Middle Pleistocene led to capture of the basin and its definitive extinction after MIS 12. These data substantially improve previous knowledge of the chronology and sedimentary evolution of the succession, providing for the first time, a well constrained chronological and palaeoenvironmental framework for the archaeological and human palaeoecological record of Valle Giumentina.

  9. Reaction dynamics of Al + O₂ → AlO + O studied by a crossed-beam velocity map imaging technique: vib-rotational state selected angular-kinetic energy distribution.

    PubMed

    Honma, Kenji; Miyashita, Kazuki; Matsumoto, Yoshiteru

    2014-06-07

    Oxidation reaction of a gas-phase aluminum atom by a molecular oxygen was studied by a crossed-beam condition at 12.4 kJ/mol of collision energy. A (1+1) resonance-enhanced multiphoton ionization (REMPI) via the D(2)Σ(+)-X(2)Σ(+) transition of AlO was applied to ionize the product. The REMPI spectrum was analyzed to determine rotational state distributions for v = 0-2 of AlO. For several vib-rotational states of AlO, state selected angular and kinetic energy distributions were determined by a time-sliced ion imaging technique for the first time. Kinetic energy distributions were well represented by that taken into account initial energy spreads of collision energy and the population of the spin-orbit levels of the counter product O((3)P(J)) determined previously. All angular distributions showed forward and backward peaks, and the forward peaks were more pronounced than the backward one for the states of low internal energy. The backward peak intensity became comparable to the forward one for the states of high internal energy. These results and the rotational state distributions suggested that the reaction proceeds via an intermediate which has a lifetime comparable to or shorter than its rotational period.

  10. Cueva Antón: A multi-proxy MIS 3 to MIS 5a paleoenvironmental record for SE Iberia

    NASA Astrophysics Data System (ADS)

    Zilhão, João; Ajas, Aurélie; Badal, Ernestina; Burow, Christoph; Kehl, Martin; López-Sáez, José Antonio; Pimenta, Carlos; Preece, Richard C.; Sanchis, Alfred; Sanz, Montserrat; Weniger, Gerd-Christian; White, Dustin; Wood, Rachel; Angelucci, Diego E.; Villaverde, Valentín; Zapata, Josefina

    2016-08-01

    Overlying a palustrine deposit of unknown age (complex FP), and protected from weathering and erosion inside a large cave/rock-shelter cavity, the sedimentary fill of Cueva Antón, a Middle Paleolithic site in SE Spain, corresponds in most part (sub-complexes AS2-to-AS5) to a ca.3 m-thick Upper Pleistocene terrace of the River Mula. Coupled with the constraints derived from the deposit's paleoclimatic proxies, OSL dating places the accumulation of this terrace in MIS 5a, and radiocarbon dates from the overlying breccia cum alluvium (sub-complex AS1) fall in the middle part of MIS 3; the intervening hiatus relates to valley incision and attendant erosion. The two intervals represented remain largely unknown in Iberia, where the archeology of the early-to-middle Upper Pleistocene is almost entirely derived from karst sites; Cueva Antón shows that this dearth of data, often interpreted in demographic terms, has depositional underpinnings ultimately determined by past climate variation. In early MIS 5a, the paleobotanical evidence indicates climate conditions similar to present, albeit wetter, followed by progressive cooling, reflected in the replacement of Aleppo pine by black pine and, at the very end, juniper-dominated landscapes - the latter characterizing also mid-MIS 3 times. The variation in sedimentary facies and composition of the mollusk assemblages reflects the changing position of the river channel relative to the back wall of the cave. Such changes represented the major constraint for the occupation of the site - most of the time inaccessible to terrestrial mammals, it was used throughout by the eagle-owl, explaining the abundance of rabbit bones. Human occupation occurred during a few, short windows of availability, and is reflected in well-preserved living floors defined by hearths, artefact scatters, and the remains of hunted herbivores. The stone tool assemblages are Middle Paleolithic, which, in Europe, implies a Neandertal identity for their makers

  11. Mullerian Inhibiting Substance (MIS) Augments IFN-Gamma Mediated Inhibition of Breast Cancer Cell Growth

    DTIC Science & Technology

    2005-06-01

    demonstrated that MIS promotes IFN-y-induced apoptosis demonstrating a functional interaction between these two classes of signaling molecules in regulation...mammary tumors which do not express ER and have functional inactivation of Rb and p53. In agreement with results observed in the transgenic mice, MIS...Interferon regulatory factor-1 (IRF-1), a gene known for its growth inhibitory functions in breast cancer cells is induced by MIS and IFN-y through a NFkB

  12. An Empirical Study about the Critical Factors Affecting MIS Students' Job Opportunities

    ERIC Educational Resources Information Center

    Fang, Xiang; Lee, Sooun

    2005-01-01

    For the first time in many years, Management Information Systems (MIS) students and faculty are seeking ways to improve full-time job placement for program graduates. Due to sharp IT budget cuts, the slowing economy, and outsourcing, job opportunities for MIS graduates have become scarcer than ever before. In addition to achieving good academic…

  13. Training for MIS in pediatric urology: proposition of a structured training curriculum

    PubMed Central

    Turrà, Francesco; Settimi, Alessandro; Esposito, Ciro

    2016-01-01

    In Europe there are a lot of training centers for minimally invasive surgery (MIS) but a standardized MIS training program in pediatric urology doesn’t exist at the moment. We performed a literature review with the last goals to propose a structured training curriculum in MIS urology for pediatric surgeons. Pediatric urologists have to obtain a valid MIS training curriculum completing the following 4 steps: (I) Theoretical part (theoretical courses, masterclass) to acquire theoretical knowledge; (II) experimental training (simulation on pelvic trainer, virtual reality simulators, animal models, 3-D ex-vivo models) to acquire basic laparoscopic skills; (III) stages in European centers of reference for pediatric MIS urology to learn all surgery aspects; (IV) personal operative experience. At the end of the training period, the trainee would be expected to perform several MIS urological procedures independently, under supervision of an expert tutor. At the end of the training program, each center will analyze the candidate training booklet and release for each applicant a certification after an exam. We think that this MIS training program in pediatric urology may assure an integrated acquisition of basic and advanced laparoscopic skills during residency training in pediatric urology. Each European country should adopt this program so as to secure a standardized technical qualification in MIS urology for all future pediatric urologists. PMID:27867857

  14. Space Station Furnace Facility Management Information System (SSFF-MIS) Development

    NASA Technical Reports Server (NTRS)

    Mead, Robert M.

    1996-01-01

    Thios report summarizes the chronology, results, and lessons learned from the development of the SSFF-MIS. This system has been nearly two years in development and has yielded some valuable insights into specialized MIS development. Attachment A contains additions, corrections, and deletions by the COTR.

  15. Mis-Education: A Recurring Theme? Transforming Black Religious and Theological Education

    ERIC Educational Resources Information Center

    Wright, Almeda M.

    2017-01-01

    Educating ministers and religious educators with the skills to connect with a variety of congregations and communities is a difficult task. Looking specifically at theological and religious education with African Americans, there are historical criticisms of "mis-education." "Mis-education" defined by Carter G. Woodson…

  16. Tropically-driven climate shifts in southwestern Europe during MIS 19, a low eccentricity interglacial

    NASA Astrophysics Data System (ADS)

    Sánchez Goñi, M. F.; Rodrigues, T.; Hodell, D. A.; Polanco-Martínez, J. M.; Alonso-García, M.; Hernández-Almeida, I.; Desprat, S.; Ferretti, P.

    2016-08-01

    The relative roles of high- versus low-latitude forcing of millennial-scale climate variability are still not well understood. Here we present terrestrial-marine climate profiles from the southwestern Iberian margin, a region particularly affected by precession, that show millennial climate oscillations related to a nonlinear response to the Earth's precession cycle during Marine Isotope Stage (MIS) 19. MIS 19 has been considered the best analogue to our present interglacial from an astronomical point of view due to the reduced eccentricity centred at 785 ka. In our records, seven millennial-scale forest contractions punctuated MIS 19 superimposed to two orbitally-driven Mediterranean forest expansions. In contrast to our present interglacial, we evidence for the first time low latitude-driven 5000-yr cycles of drying and cooling in the western Mediterranean region, along with warmth in the subtropical gyre related to the fourth harmonic of precession. These cycles indicate repeated intensification of North Atlantic meridional moisture transport that along with decrease in boreal summer insolation triggered ice growth and may have contributed to the glacial inception, at ∼774 ka. The freshwater fluxes during MIS 19ab amplified the cooling events in the North Atlantic promoting further cooling and leading to MIS 18 glaciation. The discrepancy between the dominant cyclicity observed during MIS 1, 2500-yr, and that of MIS 19, 5000-yr, challenges the similar duration of the Holocene and MIS 19c interglacials under natural boundary conditions.

  17. Different nature of glacial CaCO3 constituents between MIS 2 and MIS 12 in the East Sea/Japan Sea and its paleoceanographic implication

    NASA Astrophysics Data System (ADS)

    Khim, Boo-Keun; Tada, Ryuji; Itaki, Takuya

    2014-05-01

    Two piston cores (PC-05 and PC-08) were collected on the Yamato Rise in the East Sea/Japan Sea during the KR07-12 cruise. A composite core was achieved with the successful replacement of almost half of the upper part of core PC-05 by the entirety of core PC-08 based on the co-equivalence of L* values and the dark layers, because an interval (170 cm to 410 cm) of core PC-05 was considerably disturbed due to fluidization during the core execution. Chronostratigraphy of the composite core was constructed by the direct comparison of L* values to the well-dated core MD01-2407 that was obtained in the Oki Ridge. The lower-bottom of the composite core reached back to Marine Isotope Stage (MIS) 14, based on the age estimate by LR04 stacks. Downcore opal variation of the composite core exhibited the distinct orbital-scale cyclic changes; high during the interglacial and low during the glacial periods. However, downcore CaCO3 variation showed no corresponding orbital-scale cyclic change between glacial and interglacial periods. Some intervals of both periods were high in CaCO3 content. Frequent and large fluctuations in CaCO3 content seemed to be more related to the presence of dark layers containing thin lamination (TL) within the glacial and interglacial intervals. It is worthy to note that MIS 2 and MIS 12 are characterized by distinctly high CaCO3 content, showing up to 18% and 73%, respectively, among the glacial periods. Furthermore, in terms of lithology, MIS 2 was characterized by a thick dark layer (low L* values) with TL, whereas MIS 12 preserved the distinctly light layer (high L* values) with parallel laminations. Another remarkable dissimilarity between MIS 2 and MIS 12 was the nature of their CaCO3 constituent; the CaCO3 constituent of MIS 2 consisted of mostly planktonic foraminifera, whereas that of MIS 12 was mostly dump of coccolithophorids, regardless the presence of planktonic foraminifera. The distinctness of the CaCO3 constituents between MIS 2 and MIS

  18. El Nino Activity During MIS 5e in Peru

    NASA Astrophysics Data System (ADS)

    Rein, B.; Sirocko, F.

    2004-12-01

    Oceanography and climate along the coast of Peru is fundamentally linked to ENSO variability with stronger lithic flux into the sea and reduced marine bioproductivity during El Nino events. A 19 m long piston core with laminated marine sediments has been recovered on the edge of the Peruvian shelf (12 03'S, 77 40W, 184 m waterdepth) during cruise Sonne-147 in 2000. We present the lower 6 meters of this core that cover the time between 100 to 130 kyr before the present (BP). SST has been estimated from alkenone analysis with a mean temporal resolution of 300 years. Color logging along the core at 2 mm intervals revealed high resolution proxy data (3 to 30 a) for the precipitation on the continent (fine-grained lithics) and marine bioproduction (photosynthesis pigments: chlorines, carotenoids). Proxy data show that a major change occurred around 123 kyr BP. Mean sedimentation rate which is largely controlled by lithics dropped from 40-70 cm/kyr to 18 cm/kyr after 123 kyr BP. Contemporaneously SST start to decline towards the early Glacial level that is reached between 118 to 116 ka during the time of glacial inception. We conclude that stronger El Nino floods occurred before 123 kyr BP and El Ninos were weaker during the second half of MIS 5e. The change to weaker ENSO activity in Peru is therewith roughly contemporaneous with the beginning cooling in Greenland.

  19. Do Null Subjects (mis-)Trigger Pro-drop Grammars?

    PubMed

    Frazier, Lyn

    2015-12-01

    Native speakers of English regularly hear sentences without overt subjects. Nevertheless, they maintain a [−pro] grammar that requires sentences to have an overt subject. It is proposed that listeners of English recognize that speakers reduce predictable material and thus attribute null subjects to this process, rather than changing their grammars to a [−pro] setting. Mack et al. (J Memory Lang 67(1):211-223, 2012) showed that sentences with noise covering the subject are analyzed as having null subjects more often with a first person pronoun and with a present tense--properties correlated with more predictable referents--compared to a third person pronoun and past tense. However, those results might in principle have been due to reporting null subjects for verbs that often occur with null subjects. An experiment is reported here in which comparable results are found for sentences containing nonsense verbs. Participants preferred a null subject more often for first person present tense sentences than for third person past tense sentences. The results are as expected if participants are responding to predictability, the likelihood of reduction, rather than to lexical statistics. The results are argued to be important in removing a class of mis-triggering examples from the language acquisition problem.

  20. AMH/MIS as a contraceptive that protects the ovarian reserve during chemotherapy

    PubMed Central

    Kano, Motohiro; Sosulski, Amanda E.; Zhang, LiHua; Saatcioglu, Hatice D.; Wang, Dan; Nagykery, Nicholas; Sabatini, Mary E.; Gao, Guangping; Donahoe, Patricia K.; Pépin, David

    2017-01-01

    The ovarian reserve represents the stock of quiescent primordial follicles in the ovary which is gradually depleted during a woman’s reproductive lifespan, resulting in menopause. Müllerian inhibiting substance (MIS) (or anti-Müllerian hormone/AMH), which is produced by granulosa cells of growing follicles, has been proposed as a negative regulator of primordial follicle activation. Here we show that long-term parenteral administration of superphysiological doses of MIS, using either an adeno-associated virus serotype 9 (AAV9) gene therapy vector or recombinant protein, resulted in a complete arrest of folliculogenesis in mice. The ovaries of MIS-treated mice were smaller than those in controls and did not contain growing follicles but retained a normal ovarian reserve. When mice treated with AAV9/MIS were paired with male breeders, they exhibited complete and permanent contraception for their entire reproductive lifespan, disrupted vaginal cycling, and hypergonadotropic hypogonadism. However, when ovaries from AAV9-MIS–treated mice were transplanted orthotopically into normal recipient mice, or when treatment with the protein was discontinued, folliculogenesis resumed, suggesting reversibility. One of the important causes of primary ovarian insufficiency is chemotherapy-induced primordial follicle depletion, which has been proposed to be mediated in part by increased activation. To test the hypothesis that MIS could prevent chemotherapy-induced overactivation, mice were given carboplatin, doxorubicin, or cyclophosphamide and were cotreated with AAV9-MIS, recombinant MIS protein, or vehicle controls. We found significantly more primordial follicles in MIS-treated animals than in controls. Thus treatment with MIS may provide a method of contraception with the unique characteristic of blocking primordial follicle activation that could be exploited to prevent the primary ovarian insufficiency often associated with chemotherapy. PMID:28137855

  1. Quenching and stabilization of MIS retorts: Bench-scale experiments

    SciTech Connect

    Barbour, F.A.; Boysen, J.E.

    1991-04-01

    This research was conducted to evaluate in situ retort stabilization methods. The objective of the bench-scale simulations was to evaluate possible post-retorting operations procedures for the optimum cleaning of spent retorts. After simulating conditions of modified in situ (MIS) retorts at the time retorting had ended, procedures to accelerate retort cleanup without using large volumes of water were investigated. Samples from various levels of the retort were used to determine the amount of water-soluble constituents in the spent shale and the rehydration characteristics of the spent shale. The organic material that remained after retorting was most effectively removed from the retort by the use of reverse combustion. The removal of the organic material in this manner cracked the oil on the unretorted shale and removed heat from the bottom of the retort. Both were then transported toward the top of the retort. Unretorted kerogen was coked as it emerged from the shale near the reverse-combustion front. The reverse-combustion technique had an additional benefit in that the carbon deposited on the spent shale in the combusted zone appeared to provide a barrier to rehydration of the shale on introduction of water into the retorts. A hot quench immediately following retorting was also relatively effective in removing organic material from the retort. However, the quench did leave some organic material on the unretorted shale. This material was not readily removed by water leaching during laboratory testing. A deluge of water on a cool retort did not efficiently remove the organic material from the unretorted shale nor did the addition of a biodegradable detergent.

  2. The Role of Vitamin D Stimulation of Mullerian Inhibiting Substance (MIS) in Prostate Cancer Therapy

    DTIC Science & Technology

    2008-12-01

    calcitriol and MIS achieve increased potency to inhibit prostate cancer cell growth compared to either drug alone. However, this has not yet been...combination was no better than either drug alone. And the findings differed from the first experiment where MIS showed no anti-proliferative activity. Figure...always to a greater extent. However, we did not find that any of the genes exhibited enhancement when both drugs were used. In fact, many of the genes

  3. Speleothem evidence for MIS 5c and 5a sea level above modern level at Bermuda

    NASA Astrophysics Data System (ADS)

    Wainer, Karine A. I.; Rowe, Mark P.; Thomas, Alexander L.; Mason, Andrew J.; Williams, Bruce; Tamisiea, Mark E.; Williams, Felicity H.; Düsterhus, André; Henderson, Gideon M.

    2017-01-01

    The history of sea level in regions impacted by glacio-isostasy provides constraints on past ice-sheet distribution and on the characteristics of deformation of the planet in response to loading. The Western North Atlantic-Caribbean region, and Bermuda in particular, is strongly affected by the glacial forebulge that forms as a result of the Laurentide ice-sheet present during glacial periods. The timing of growth of speleothems, at elevations close to sea level can provide records of minimum relative sea level (RSL). In this study we used U-Th dating to precisely date growth periods of speleothems from Bermuda which were found close to modern-day sea level. Results suggest that RSL at this location was above modern during MIS5e, MIS5c and MIS5a. These data support controversial previous indications that Bermudian RSL was significantly higher than RSL at other locations during MIS 5c and MIS 5a. We confirm that it is possible to explain a wide range of MIS5c-a relative sea levels observed across the Western North Atlantic-Caribbean in glacial isostatic adjustment models, but only with a limited range of mantle deformation constants. This study demonstrates the particular power of Bermuda as a gauge for response of the forebulge to glacial loading, and demonstrates the potential for highstands at this location to be significantly higher than in other regions, helping to explain the high sea levels observed for Bermuda from earlier highstands.

  4. Speleothem record of the last 180 ka in Villars cave (SW France): Investigation of a large δ18O shift between MIS6 and MIS5

    NASA Astrophysics Data System (ADS)

    Wainer, K.; Genty, D.; Blamart, D.; Daëron, M.; Bar-Matthews, M.; Vonhof, H.; Dublyansky, Y.; Pons-Branchu, E.; Thomas, L.; van Calsteren, P.; Quinif, Yves; Caillon, N.

    2011-01-01

    The Vil-car-1 flowstone core from Villars cave (SW France) provides one of the first European speleothem records extending back to 180 ka, based on U-Th TIMS and MC-ICP-MS measurements. The core offers a continuous record of Termination II and the Last Interglacial. The penultimate deglaciation is characterized by a prominent 5‰ depletion in calcite δ18O. Determining which specific environmental factors controlled such a large oxygen isotopic shift offers the opportunity to assess the impact of various factors influencing δ18O variations in speleothem calcite. Oxygen isotope analyses of fluid inclusions indicate that drip water δ18O remained within a very narrow range of ±1‰ from Late MIS6 to the MIS5 δ18O optimum. The possibility of such a stable behaviour is supported by simple calculations of various effects influencing seepage water δ18O. Although this could suggest that the isotopic shift in calcite is mainly driven by temperature increase, attempts to quantify the temperature shift from Late MIS6 to the MIS5 δ18O optimum by assuming an equilibrium relationship between calcite and fluid inclusion δ18O yield unreasonably high estimates of ˜20 °C warming and Late MIS6 cave temperatures below 0 °C; this suggests that the flowstone calcite precipitated out of thermodynamic equilibrium at this site. Using a method proposed by Guo et al. (submitted for publication) combining clumped isotope measurements, fluid inclusion and modern calcite δ18O analyses, it is possible to quantitatively correct for isotopic disequilibrium and estimate absolute paleotemperatures. Although the precision of these absolute temperature reconstructions is limited by analytical uncertainties, the temperature rise between Late MIS6 and the MIS5 optimum can be robustly constrained between 13.2 ± 2.6 and 14.6 ± 2.6 °C (1σ), consistent with existing estimates from Western Europe pollen and sea-surface temperature records.

  5. Skin-Specific Deletion of Mis18α Impedes Proliferation and Stratification of Epidermal Keratinocytes.

    PubMed

    Park, Koog Chan; Lee, Minkyoung; Jeon, Yoon; Jeon, Raok; Baek, Sung Hee; Lee, Ho; Kim, Keun Il

    2017-02-01

    The Mis18 proteins (Mis18α, Mis18β, and M18BP1) are pivotal to the deposition of CENP-A at the centromere during cell cycle progression and are indispensable for embryonic development. Here, we show that Mis18α is critical for the proliferation of keratinocytes and stratification of the epidermis. Mice lacking Mis18α in the epidermis died shortly after birth, showing skin abnormalities like thin and translucent skin and defective skin barrier functions. The epidermis of newborn Mis18α-deficient mice lacked distinct stratification and mature hair follicles, with a reduction in the number of proliferating cells and increased cell death in the basal layer. Earlier expression of the Cre recombinase from keratin-14 promoter in the ventral region resulted in earlier keratinocyte death in the ventral part compared with the dorsal part in the absence of Mis18α, leading to more severe malformation of the ventral epidermal layers. As observed in Mis18α-deficient mouse keratinocytes, knockdown of Mis18α in HaCaT cells caused marked loss of centromeric CENP-A dots and chromosomal misalignment. Overall, we propose that Mis18α is important for epidermal cell proliferation and stratification, because it is required for the deposition of CENP-A at the centromeric nucleosomes.

  6. Similar millennial climate variability on the Iberian margin during two early Pleistocene glacials and MIS 3

    NASA Astrophysics Data System (ADS)

    Birner, B.; Hodell, D. A.; Tzedakis, P. C.; Skinner, L. C.

    2016-01-01

    Although millennial-scale climate variability (<10 ka) has been well studied during the last glacial cycles, little is known about this important aspect of climate in the early Pleistocene, prior to the Middle Pleistocene Transition. Here we present an early Pleistocene climate record at centennial resolution for two representative glacials (marine isotope stages (MIS) 37-41 from approximately 1235 to 1320 ka) during the "41 ka world" at Integrated Ocean Drilling Program Site U1385 (the "Shackleton Site") on the southwest Iberian margin. Millennial-scale climate variability was suppressed during interglacial periods (MIS 37, MIS 39, and MIS 41) and activated during glacial inceptions when benthic δ18O exceeded 3.2‰. Millennial variability during glacials MIS 38 and MIS 40 closely resembled Dansgaard-Oeschger events from the last glacial (MIS 3) in amplitude, shape, and pacing. The phasing of oxygen and carbon isotope variability is consistent with an active oceanic thermal bipolar see-saw between the Northern and Southern Hemispheres during most of the prominent stadials. Surface cooling was associated with systematic decreases in benthic carbon isotopes, indicating concomitant changes in the meridional overturning circulation. A comparison to other North Atlantic records of ice rafting during the early Pleistocene suggests that freshwater forcing, as proposed for the late Pleistocene, was involved in triggering or amplifying perturbations of the North Atlantic circulation that elicited a bipolar see-saw response. Our findings support similarities in the operation of the climate system occurring on millennial time scales before and after the Middle Pleistocene Transition despite the increases in global ice volume and duration of the glacial cycles.

  7. New evidence for complex climate change in MIS 11 from Hoxne, Suffolk, UK

    PubMed Central

    Ashton, Nick; Lewis, Simon G.; Parfitt, Simon A.; Penkman, Kirsty E.H.; Russell Coope, G.

    2008-01-01

    The climatic signal of Marine Isotope Stage (MIS) 11 is well-documented in marine and ice-sheet isotopic records and is known to comprise at least two major warm episodes with an intervening cool phase. Terrestrial records of MIS 11, though of high resolution, are often fragmentary and their chronology is poorly constrained. However, some notable exceptions include sequences from the maar lakes in France and Tenaghi Philippon in Greece. In the UK, the Hoxnian Interglacial has been considered to correlate with MIS 11. New investigations at Hoxne (Suffolk) provide an opportunity to re-evaluate the terrestrial record of MIS 11. At Hoxne, the type Hoxnian Interglacial sediments are overlain by a post-Hoxnian cold-temperate sequence. The interglacial sediments and the later temperate phase are separated by the so-called ‘Arctic Bed’ from which cold-climate macroscopic plant and beetle remains have been recovered. The later temperate phase was deposited during an episode of boreal woodland and is associated with the artefacts, a diverse vertebrate fauna and molluscs. New amino acid geochronological data and biostratigraphical considerations suggest that the post-Hoxnian sequence correlates with late substages of MIS 11. The paper further investigates the correlation of the sequence at Hoxne with the palynological sequences found elsewhere in Europe and adjacent offshore areas. PMID:19777138

  8. Ice Complex formation in arctic East Siberia during the MIS3 Interstadial

    NASA Astrophysics Data System (ADS)

    Wetterich, Sebastian; Tumskoy, Vladimir; Rudaya, Natalia; Andreev, Andrei A.; Opel, Thomas; Meyer, Hanno; Schirrmeister, Lutz; Hüls, Matthias

    2014-01-01

    A continuous 15 m long sequence of Ice Complex permafrost (Yedoma) exposed in a thermo-cirque at the southern coast of Bol'shoy Lyakhovsky Island (New Siberian Archipelago, Dmitry Laptev Strait) was studied to reconstruct past landscape and environmental dynamics. The sequence accumulated during the Marine Isotope Stage 3 (MIS3) Interstadial between >49 and 29 ka BP in an ice-wedge polygon. The frozen deposits were cryolithologically described and sampled on a vertical bluff between two ice wedges. According to sedimentological and geochronological data, the section is subdivided into three units which correlate with environmental conditions of the early, middle, and late MIS3 period. Palynological data support this stratification. The stable isotope signature of texture ice in the polygon structure reflects fractionation due to local freeze-thaw processes, while the signature of an approximately 5 m wide and more than 17 m high ice wedge fits very well into the regional stable-water isotope record. Regional climate dynamics during the MIS3 Interstadial and local landscape conditions of the polygonal patterned ground controlled the Ice Complex formation. The sequence presented here completes previously published MIS3 permafrost records in Northeast Siberia. Late Quaternary stadial-interstadial climate variability in arctic West Beringia is preserved at millennial resolution in the Ice Complex. A MIS3 climate optimum was revealed between 48 and 38 ka BP from the Ice Complex on Bol'shoy Lyakhovsky Island.

  9. Stable Isotope and Trace Element Records of Parts of MIS 5 and MIS 6 from Stalagmites from Lehman Cave, Nevada, USA

    NASA Astrophysics Data System (ADS)

    Cross, M.; McGee, D.; Broecker, W. S.; Quade, J.; Cheng, H.; Edwards, R. L.

    2014-12-01

    Recent years have seen the advent of high-resolution speleothem paleoclimate records from the Great Basin, adding to and refining our knowledge of the timing, duration, and nature of glacial/interglacial periods and transitions in Western North America from lake records and other archives of paleoclimatic change. Here we present a record of isotopic and geochemical change in stalagmites from Lehman Cave, (39.01°N, 114.22°W), a well-decorated cave on the western edge of the Bonneville Basin. These slow-growth stalagmites are 230Th dated to portions of Marine Isotope Stages 5 and 6. They replicate, at least in part, an orbitally-consistent Termination II (T-II) at 131 + 2 ka, first demonstrated in Great Basin speleothems by Shakun et al. (2011). T-II is expressed in our record as a +5.5‰ (from -7.5 to -2 ‰) and nearly +4‰ (from -14.4 to -10.5‰, when corrected for sea level) shift in δ13C and δ18O, respectively. There are notable similarities and differences among our record and other Great Basin records, Devils Hole (Winograd et al. 1992) and the recent speleothem records by Lachniet et al. (2014) and Denniston et al. (2007). Our record, for example, does not agree with the early timing of T-II in Devils Hole. However, during the latter portion of MIS 5, our record exhibits oxygen isotope values (-13 to -14‰ VPDB) significantly lighter than those in MIS 5e (-10.5 to -11‰ VPDB), similar to Devils Hole and Goshute Cave. In contrast, correlative values in Leviathan Cave (Lachniet et al., 2014) during the latter part of MIS5 are up to 3‰ heavier: -10.5‰ VPDB, matching MIS 5e values. Additionally, the lowest MIS 6 oxygen isotopic values in our record are reached at approximately 137.5 ± 2 ka, about 4 ka earlier than in the Lehman Cave sample presented in the Lachniet et al. record. We evaluate several potential explanations for these offsets in the MIS 5 samples, for example, variable degrees of isotopic enrichment. As a step towards reconciling these

  10. A multi-proxy record of MIS 11-12 deglaciation and glacial MIS 12 instability from the Sulmona basin (central Italy)

    NASA Astrophysics Data System (ADS)

    Regattieri, Eleonora; Giaccio, Biagio; Galli, Paolo; Nomade, Sebastien; Peronace, Edoardo; Messina, Paolo; Sposato, Andrea; Boschi, Chiara; Gemelli, Maurizio

    2016-01-01

    A multi-proxy record (lithology, XRF, CaCO3 content, carbonate δ18O and δ13C) was acquired from a sediment core drilled in the intermountain Sulmona basin (central Italy). Tephrostratigraphic analyses of three volcanic ash layers ascribe the investigated succession to the MIS 12-MIS 11 period, spanning the interval ca. 500-410 ka. Litho-pedo facies assemblage indicates predominant lacustrine deposition, interrupted by a minor sub-aerial and lake low stand episode. Variations in major and minor elements concentrations are related to changes in the clastic input to the lake. The oxygen isotopic composition of carbonate (δ18Oc) intervals is interpreted mainly as a proxy for the amount of precipitation in the high-altitude catchment of the karst recharge system. The record shows pronounced hydrological variability at orbital and millennial time-scales, which appears closely related to the Northern Hemisphere summer insolation pattern and replicates North Atlantic and west Mediterranean Sea Surface Temperature (SST) fluctuations. The MIS 12 glacial inception is marked by an abrupt reduction of precipitation, lowering of the lake level and enhanced catchment erosion. A well-defined and isotopically prominent interstadial with increased precipitation maybe related to insolation maxima-precession minima at ca. 465 ka. This interstadial ends abruptly at ca. 457 ka and it is followed by a phase of strong short-term instability. Drastic lake-level lowering and enhanced clastic flux characterized the MIS 12 glacial maximum. Lacustrine deposition restarted about 440 ka ago. The MIS 12-MIS 11 transition is characterized by a rapid increase in the precipitation, lake-level rise and reduction in the clastic input, interrupted by a short and abrupt return to drier conditions. Comparison with marine records from the Iberian margin and western Mediterranean suggests that major events of ice rafted debris deposition, related to southward migrations of the polar front, match the

  11. Studies of Large-Area Inversion-Layer Metal-Insulator-Semiconductor (IL/MIS) Solar Cells and Arrays

    NASA Technical Reports Server (NTRS)

    Ho, Fat Duen

    1996-01-01

    Many inversion-layer metal-insulator-semiconductor (IL/MIS) solar cells have been fabricated. There are around eighteen 1 cm(exp 2) IL/MIS solar cells which have efficiencies greater than 7%. There are only about three 19 cm(exp 2) IL/MIS cells which have efficiencies greater than 4%. The more accurate control of the thickness of the thin layer of oxide between aluminum and silicon of the MIS contacts has been achieved. A lot of effort and progress have been made in this area. A comprehensive model for MIS contacts under dark conditions has been developed that covers a wide range of parameters. It has been applied to MIS solar cells. One of the main advantages of these models is the prediction of the range of the thin oxide thickness versus the maximum efficiencies of the MIS solar cells. This is particularly important when the thickness is increased to 25 A. This study is very useful for our investigation of the IL/MIS solar cells. The two-dimensional numerical model for the IL/MIS solar cells has been tried to develop and the results are presented in this report.

  12. Late quaternary sea level changes of Gabes coastal plain and shelf: Identification of the MIS 5c and MIS 5a onshore highstands, southern Mediterranean

    NASA Astrophysics Data System (ADS)

    Gzam, Maher; Mejdoub, Noureddine El; Jedoui, Younes

    2016-02-01

    The continental shelf of the Gulf of Gabes is outlined, during the MIS 5c and MIS 5a onshore highstands, by the genesis of forced regressive beach ridges situated respectively at -19 m b.s.l/100 ka and -8 m b.s.l/80 ka. This area, considered as a stable domain since at least the last 130 ka (Bouaziz et al. 2003), is a particular zone for the reconstruction of the late quaternary sea-level changes in the region. Shuttle Radar Topography Mission (SRTM) data and field observations are highlighted to deduce interaction between hydrodynamic factors and antecedent topography. Variations in geomorphology were attributed to geological inheritance. Petrography and sedimentary facies of the submerged coastal ridges reveal that the palaeocoastal morphology was more agitated than today and the fluvial discharges are consistent. Actual morphologic trend deduced from different environment coasts (sandy coasts, sea cliffs and tidal flat) is marked by accumulation of marine sands and progradation.

  13. The response of SST to insolation and ice sheet variability from MIS 3 to MIS 11 in the northwestern Mediterranean Sea (Gulf of Lions)

    NASA Astrophysics Data System (ADS)

    Cortina, Aleix; Sierro, Francisco Javier; Flores, José Abel; Martrat, Belen; Grimalt, Joan O.

    2015-12-01

    Here we present a sea surface temperature (SST) record based on the Uk'37 index from the PRGL1 borehole (Promess1) drilled on the upper slope of the Gulf of Lions (GL). This is the first continuous and high-resolution record in the northwestern Mediterranean Sea from marine oxygen isotope stage 3 (MIS) 3 to MIS 11. Due the location of the GL, the SST proxy can be considered to be a reliable tool to study the climate link between high latitude and midlatitude. During glacial inceptions, the northern ice sheet signal via cold northwesterly winds was first recorded in our study area in comparison with southern locations, highlighting the strong sensitivity of this location to high-latitude dynamics. Moreover, the amplitude of the millennial-scale variability in the western Mediterranean basin seems to be the result of both ice sheet and insolation variability.

  14. Exposure dating and glacial reconstruction at Mt. Field, Tasmania, Australia, identifies MIS 3 and MIS 2 glacial advances and climatic variability

    NASA Astrophysics Data System (ADS)

    Mackintosh, A. N.; Barrows, T. T.; Colhoun, E. A.; Fifield, L. K.

    2006-05-01

    Tasmania is important for understanding Quaternary climatic change because it is one of only three areas that experienced extensive mid-latitude Southern Hemisphere glaciation and it lies in a dominantly oceanic environment at a great distance from Northern Hemisphere ice sheet feedbacks. We applied exposure dating using 36Cl to an extensive sequence of moraines from the last glacial at Mt. Field, Tasmania. Glaciers advanced at 41-44 ka during Marine oxygen Isotope Stage (MIS) 3 and at 18 ka during MIS 2. Both advances occurred in response to an ELA lowering greater than 1100 m below the present-day mean summer freezing level, and a possible temperature reduction of 7-8°C. Deglaciation was rapid and complete by ca. 16 ka. The overall story emerging from studies of former Tasmanian glaciers is that the MIS 2 glaciation was of limited extent and that some glaciers were more extensive during earlier parts of the last glacial cycle. Copyright

  15. An Auto-management Thesis Program WebMIS Based on Workflow

    NASA Astrophysics Data System (ADS)

    Chang, Li; Jie, Shi; Weibo, Zhong

    An auto-management WebMIS based on workflow for bachelor thesis program is given in this paper. A module used for workflow dispatching is designed and realized using MySQL and J2EE according to the work principle of workflow engine. The module can automatively dispatch the workflow according to the date of system, login information and the work status of the user. The WebMIS changes the management from handwork to computer-work which not only standardizes the thesis program but also keeps the data and documents clean and consistent.

  16. Differentiation of MIS 9 and MIS 11 in the continental record: vegetational, faunal, aminostratigraphic and sea-level evidence from coastal sites in Essex, UK

    PubMed Central

    Roe, Helen M.; Coope, G. Russell; Devoy, Robert J.N.; Harrison, Colin J.O.; Penkman, Kirsty E.H.; Preece, Richard C.; Schreve, Danielle C.

    2009-01-01

    Multidisciplinary investigations of the vegetational, faunal and sea-level history inferred from the infills of buried channels on the coast of eastern Essex have a direct bearing on the differentiation of MIS 11 and MIS 9 in continental records. New data are presented from Cudmore Grove, an important site on Mersea Island that can be linked to the terrace sequence of the River Thames. The vegetational history has been reconstructed from a pollen sequence covering much of the interglacial represented. The temperate nature of the climate is apparent from a range of fossil groups, including plant remains, vertebrates (especially the rich herpetofauna), molluscs and beetles, which all have strong thermophilous components. The beetle data have been used to derive a Mutual Climatic Range reconstruction, suggesting that mean July temperatures were about 2 °C warmer than modern values for southeast England, whereas mean January temperatures may have been slightly colder. The sea-level history has been reconstructed from the molluscs, ostracods and especially the diatoms, which indicate that the marine transgression occurred considerably earlier in the interglacial cycle than at the neighbouring Hoxnian site at Clacton. There are a number of palynological similarities between the sequence at Cudmore Grove and Clacton, especially the presence of Abies and the occurrence of Azolla filiculoides megaspores. Moreover, both sites have yielded Palaeolithic archaeology, indeed the latter is the type site of the Clactonian (flake-and-core) industry. However, the sites can be differentiated on the basis of mammalian biostratigraphy, new aminostratigraphic data, as well as the differences in the sea-level history. The combined evidence suggests that the infill of the channel at Cudmore Grove accumulated during MIS 9, whereas the deposits at Clacton formed during MIS 11. The infill of a much later channel, yielding non-marine molluscs and vertebrates including Hippopotamus, appears

  17. Differentiation of MIS 9 and MIS 11 in the continental record: vegetational, faunal, aminostratigraphic and sea-level evidence from coastal sites in Essex, UK

    NASA Astrophysics Data System (ADS)

    Roe, Helen M.; Coope, G. Russell; Devoy, Robert J. N.; Harrison, Colin J. O.; Penkman, Kirsty E. H.; Preece, Richard C.; Schreve, Danielle C.

    2009-11-01

    Multidisciplinary investigations of the vegetational, faunal and sea-level history inferred from the infills of buried channels on the coast of eastern Essex have a direct bearing on the differentiation of MIS 11 and MIS 9 in continental records. New data are presented from Cudmore Grove, an important site on Mersea Island that can be linked to the terrace sequence of the River Thames. The vegetational history has been reconstructed from a pollen sequence covering much of the interglacial represented. The temperate nature of the climate is apparent from a range of fossil groups, including plant remains, vertebrates (especially the rich herpetofauna), molluscs and beetles, which all have strong thermophilous components. The beetle data have been used to derive a Mutual Climatic Range reconstruction, suggesting that mean July temperatures were about 2 °C warmer than modern values for southeast England, whereas mean January temperatures may have been slightly colder. The sea-level history has been reconstructed from the molluscs, ostracods and especially the diatoms, which indicate that the marine transgression occurred considerably earlier in the interglacial cycle than at the neighbouring Hoxnian site at Clacton. There are a number of palynological similarities between the sequence at Cudmore Grove and Clacton, especially the presence of Abies and the occurrence of Azolla filiculoides megaspores. Moreover, both sites have yielded Palaeolithic archaeology, indeed the latter is the type site of the Clactonian (flake-and-core) industry. However, the sites can be differentiated on the basis of mammalian biostratigraphy, new aminostratigraphic data, as well as the differences in the sea-level history. The combined evidence suggests that the infill of the channel at Cudmore Grove accumulated during MIS 9, whereas the deposits at Clacton formed during MIS 11. The infill of a much later channel, yielding non-marine molluscs and vertebrates including Hippopotamus, appears

  18. Mapping the MIS Curriculum Based on Critical Skills of New Graduates: An Empirical Examination of IT Professionals

    ERIC Educational Resources Information Center

    Downey, James P.; McMurtrey, Mark E.; Zeltmann, Steven M.

    2008-01-01

    MIS curricula research almost always focuses on either curriculum issues or the critical skills required of new MIS graduates, rarely both. This study examines both by determining the critical skills required of new graduates, from the perspective of IT professionals in the field, then uniquely mapping those skills into a comprehensive yet…

  19. 49 CFR Appendix H to Part 40 - DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., App. H Appendix H to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data... 49 Transportation 1 2010-10-01 2010-10-01 false DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form H Appendix H to Part 40 Transportation Office of the...

  20. 49 CFR Appendix H to Part 40 - DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., App. H Appendix H to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data... 49 Transportation 1 2014-10-01 2014-10-01 false DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form H Appendix H to Part 40 Transportation Office of the...

  1. 49 CFR Appendix H to Part 40 - DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., App. H Appendix H to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data... 49 Transportation 1 2013-10-01 2013-10-01 false DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form H Appendix H to Part 40 Transportation Office of the...

  2. 49 CFR Appendix H to Part 40 - DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., App. H Appendix H to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data... 49 Transportation 1 2011-10-01 2011-10-01 false DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form H Appendix H to Part 40 Transportation Office of the...

  3. 49 CFR Appendix H to Part 40 - DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., App. H Appendix H to Part 40—DOT Drug and Alcohol Testing Management Information System (MIS) Data... 49 Transportation 1 2012-10-01 2012-10-01 false DOT Drug and Alcohol Testing Management Information System (MIS) Data Collection Form H Appendix H to Part 40 Transportation Office of the...

  4. The Inchworm and the Nightingale: On the (Mis)use of Data in Music Teacher Evaluation

    ERIC Educational Resources Information Center

    Robinson, Mitchell

    2015-01-01

    The music education profession is faced with two serious problems regarding the (mis)use of data in music teacher evaluation. The first has to do with the quality and kinds of data that music teachers have been forced to use; the second is concerned with how these data are being used in the music teacher evaluation process. The evidence I will use…

  5. MIS versus Computer Science: An Empirical Comparison of the Influences on the Students' Choice of Major

    ERIC Educational Resources Information Center

    Downey, James P.; McGaughey, Ronnie; Roach, David

    2009-01-01

    A history of declining enrollments in university Management Information Systems (MIS) and computer science (CS) departments in the U.S. considerably impacts both college departments and business organizations that hire graduates. In order to reverse the enrollment trend, an understanding of the important similarities and differences that shape a…

  6. Millennial-scale climate instabilities in the subtropical Atlantic during MIS 6 and 7

    NASA Astrophysics Data System (ADS)

    Scheinwald, A.; Billups, K.

    2012-12-01

    We have constructed a high resolution (~200 year) planktonic foraminiferal stable isotope record spanning Marine Isotope Stages (MIS) 6 and 7 in the subtropical Atlantic (ODP Site 1059). The record fills a gap in a ~1 million year long time series of millennial-scale surface ocean hydrography in this region. Our ultimate goal is to test the hypothesis that millennial-scale climate signals in the northwestern subtropical Atlantic are linked to external driving factors such as the harmonics of precession. Results show that longer-term trends in the oxygen isotope data spanning MIS 6-7 closely follow precessional forcing allowing us to refine the original age model of Grützner et al. (2002). High frequency variations are superimposed on the long-term trend during both the glacial MIS 6 and the interglacial MIS 7. Spectral analyses indicate high concentration of power at millennial-scale periodicities of 10.9 kyr, 5.2 kyr, and 2.8 kyr. These periodicities are close to those expected from harmonics of precessional forcing during this interval of time (11.5 kyr, 5.8 kyr, 2.8 kyr). We will show the evolution of the millennial-scale periodicities in this region over the past 1 million years by splicing the record into published ones and unifying the age model.

  7. An Alumni Assessment of MIS Related Job Skill Importance and Skill Gaps

    ERIC Educational Resources Information Center

    Wilkerson, Jerod W.

    2012-01-01

    This paper presents the results of a job skill survey of Management Information Systems (MIS) alumni from a Northeastern U.S. university. The study assesses job skill importance and skill gaps associated with 104 technical and non-technical skill items. Survey items were grouped into 6 categories based on prior research. Skill importance and skill…

  8. An Activity Theory Approach to Analyze Barriers to a Virtual Management Information Systems (MIS) Curriculum

    ERIC Educational Resources Information Center

    Jaradat, Suhair; Qablan, Ahmad; Barham, Areej

    2011-01-01

    This paper explains how the activity theory is used as a framework to analyze the barriers to a virtual Management Information Stream (MIS) Curriculum in Jordanian schools, from both the sociocultural and pedagogical perspectives. Taking the activity system as a unit of analysis, this study documents the processes by which activities shape and are…

  9. An Empirical Examination of the Composition of Vocational Interest in Business Colleges: MIS vs. Other Majors

    ERIC Educational Resources Information Center

    Downey, James

    2011-01-01

    Given the diminishing number of Management Information Systems (MIS) majors, an understanding of the factors which influence student choice of major is crucial. It has been noted in many previous studies that interest in a major and career significantly influences the student's choice of college major; indeed, in most studies, it is the strongest…

  10. The Use of Facebook in an Introductory MIS Course: Social Constructivist Learning Environment

    ERIC Educational Resources Information Center

    Ractham, Peter; Kaewkitipong, Laddawan; Firpo, Daniel

    2012-01-01

    The major objective of this article is to evaluate via a Design Science Research Methodology (DSRM) the implementation of a Social Constructivist learning framework for an introductory Management Information System (MIS) course. Facebook was used as a learning artifact to build and foster a learning environment, and a series of features and…

  11. Transmission line relay mis-operation detection based on time-synchronized field data

    DOE PAGES

    Esmaeilian, Ahad; Popovic, Tomo; Kezunovic, Mladen

    2015-05-04

    In this paper, a real-time tool to detect transmission line relay mis-operation is implemented. The tool uses time-synchronized measurements obtained from both ends of the line during disturbances. The proposed fault analysis tool comes into the picture only after the protective device has operated and tripped the line. The proposed methodology is able not only to detect, classify, and locate transmission line faults, but also to accurately confirm whether the line was tripped due to a mis-operation of protective relays. The analysis report includes either detailed description of the fault type and location or detection of relay mis-operation. As such,more » it can be a source of very useful information to support the system restoration. The focus of the paper is on the implementation requirements that allow practical application of the methodology, which is illustrated using the field data obtained the real power system. Testing and validation is done using the field data recorded by digital fault recorders and protective relays. The test data included several hundreds of event records corresponding to both relay mis-operations and actual faults. The discussion of results addresses various challenges encountered during the implementation and validation of the presented methodology.« less

  12. First physical evidence for forested environment in the Arctic during MIS 3

    NASA Astrophysics Data System (ADS)

    Sarala, Pertti; Väliranta, Minna; Eskola, Tiina; Vaikutiené, Giedré

    2016-07-01

    Old sedimentological and geochronological records can be preserved underneath the central parts of the continental ice sheets under non-erosive, cold-based subglacial conditions. Organic deposits that predate the last deglaciation are of particular value for the information held on glacial-time climate and environmental conditions. In this study, we present multiproxy data derived from a well-preserved MIS 3 interstadial (55–25 ka ago) organic layer from inside the Arctic Circle in the Finnish Lapland. Biological proxy evidence, namely coming from aquatic plant species, indicates July temperatures as high as 14.4 °C, i.e. higher than those of today for the study site. Macrofossil evidence demonstrates for the first time the presence of pines accompanied by tree birch during the MIS 3 interstadial in northern Fennoscandia. These results concur with contemporary insolation model outcomes but contradict with the previous proxy-based view of open tundra conditions during the MIS 3. The data suggest that there are highly dynamic interstadial continental ice-sheet dynamics following changes in orbital forcing. Warm climate enabled the establishment of forests on exposed landscape. Moreover, we suggest that in the light of these new data, previous MIS 3 pollen data could be re-interpreted.

  13. First physical evidence for forested environment in the Arctic during MIS 3

    PubMed Central

    Sarala, Pertti; Väliranta, Minna; Eskola, Tiina; Vaikutiené, Giedré

    2016-01-01

    Old sedimentological and geochronological records can be preserved underneath the central parts of the continental ice sheets under non-erosive, cold-based subglacial conditions. Organic deposits that predate the last deglaciation are of particular value for the information held on glacial-time climate and environmental conditions. In this study, we present multiproxy data derived from a well-preserved MIS 3 interstadial (55–25 ka ago) organic layer from inside the Arctic Circle in the Finnish Lapland. Biological proxy evidence, namely coming from aquatic plant species, indicates July temperatures as high as 14.4 °C, i.e. higher than those of today for the study site. Macrofossil evidence demonstrates for the first time the presence of pines accompanied by tree birch during the MIS 3 interstadial in northern Fennoscandia. These results concur with contemporary insolation model outcomes but contradict with the previous proxy-based view of open tundra conditions during the MIS 3. The data suggest that there are highly dynamic interstadial continental ice-sheet dynamics following changes in orbital forcing. Warm climate enabled the establishment of forests on exposed landscape. Moreover, we suggest that in the light of these new data, previous MIS 3 pollen data could be re-interpreted. PMID:27363905

  14. Gaze-Contingent Motor Channelling, haptic constraints and associated cognitive demand for robotic MIS.

    PubMed

    Mylonas, George P; Kwok, Ka-Wai; James, David R C; Leff, Daniel; Orihuela-Espina, Felipe; Darzi, Ara; Yang, Guang-Zhong

    2012-04-01

    The success of MIS is coupled with an increasing demand on surgeons' manual dexterity and visuomotor coordination due to the complexity of instrument manipulations. The use of master-slave surgical robots has avoided many of the drawbacks of MIS, but at the same time, has increased the physical separation between the surgeon and the patient. Tissue deformation combined with restricted workspace and visibility of an already cluttered environment can raise critical issues related to surgical precision and safety. Reconnecting the essential visuomotor sensory feedback is important for the safe practice of robot-assisted MIS procedures. This paper introduces a novel gaze-contingent framework for real-time haptic feedback and virtual fixtures by transforming visual sensory information into physical constraints that can interact with the motor sensory channel. We demonstrate how motor tracking of deforming tissue can be made more effective and accurate through the concept of Gaze-Contingent Motor Channelling. The method is also extended to 3D by introducing the concept of Gaze-Contingent Haptic Constraints where eye gaze is used to dynamically prescribe and update safety boundaries during robot-assisted MIS without prior knowledge of the soft-tissue morphology. Initial validation results on both simulated and robot assisted phantom procedures demonstrate the potential clinical value of the technique. In order to assess the associated cognitive demand of the proposed concepts, functional Near-Infrared Spectroscopy is used and preliminary results are discussed.

  15. Transmission line relay mis-operation detection based on time-synchronized field data

    SciTech Connect

    Esmaeilian, Ahad; Popovic, Tomo; Kezunovic, Mladen

    2015-05-04

    In this paper, a real-time tool to detect transmission line relay mis-operation is implemented. The tool uses time-synchronized measurements obtained from both ends of the line during disturbances. The proposed fault analysis tool comes into the picture only after the protective device has operated and tripped the line. The proposed methodology is able not only to detect, classify, and locate transmission line faults, but also to accurately confirm whether the line was tripped due to a mis-operation of protective relays. The analysis report includes either detailed description of the fault type and location or detection of relay mis-operation. As such, it can be a source of very useful information to support the system restoration. The focus of the paper is on the implementation requirements that allow practical application of the methodology, which is illustrated using the field data obtained the real power system. Testing and validation is done using the field data recorded by digital fault recorders and protective relays. The test data included several hundreds of event records corresponding to both relay mis-operations and actual faults. The discussion of results addresses various challenges encountered during the implementation and validation of the presented methodology.

  16. Student Motivational Profiles in an Introductory MIS Course: An Exploratory Cluster Analysis

    ERIC Educational Resources Information Center

    Nelson, Klara

    2014-01-01

    This study profiles students in an introductory MIS course according to a variety of variables associated with choice of academic major. The data were collected through a survey administered to 12 sections of the course. A two-step cluster analysis was performed with gender as a categorical variable and students' perceptions of task value…

  17. Minimally Invasive Direct Thoracic Interbody Fusion (MIS-DTIF): Technical Notes of a Single Surgeon Study

    PubMed Central

    Abbasi, Hamid

    2016-01-01

    Background Minimally invasive direct thoracic interbody fusion (MIS-DTIF) is a new single surgeon procedure for fusion of the thoracic vertebrae below the scapula (T6/7) to the thoracolumbar junction. In this proof of concept study, we describe the surgical technique for MIS-DTIF and report our experience and the perioperative outcomes of the first four patients who underwent this procedure. Study design/setting In this study we attempt to establish the safety and efficacy of MIS-DTIF. We have performed MIS-DTIF on six spinal levels in four patients with degenerative disk disease or disk herniation. We recorded surgery time, blood loss, fluoroscopy time, complications, and patient-reported pain. Methods Throughout the MIS-DTIF procedure, the surgeon is aided by biplanar fluoroscopic imaging and electrophysiological monitoring. The surgeon approaches the spine with a series of gentle tissue dilations and inserts a working tube that establishes a direct connection from the outside of the skin to the disk space. Through this working tube, the surgeon performs a discectomy and inserts an interbody graft or cage. The procedure is completed with minimally invasive (MI) posterior pedicle screw fixation. Results For the single level patients the mean blood loss was 90 ml, surgery time 43 minutes, fluoroscopy time 293 seconds, and hospital stay two days. For the two-level surgeries, the mean blood loss was 27 ml, surgery time 61 minutes, fluoroscopy time 321 seconds, and hospital stay three days. We did not encounter any clinically significant complications. Thirty days post-surgery, the patients reported a statistically significant reduction of 5.3 points on a 10-point sliding pain scale. Conclusions MIS-DTIF with pedicle screw fixation is a safe and clinically effective procedure for fusions of the thoracic spine. The procedure is technically straightforward and overcomes many of the limitations of the current minimally invasive (MI) approaches to the thoracic spine. MIS

  18. Global sea-level fluctuations during the Last Interglaciation (MIS 5e)

    NASA Astrophysics Data System (ADS)

    Hearty, Paul J.; Hollin, John T.; Neumann, A. Conrad; O'Leary, Michael J.; McCulloch, Malcolm

    2007-09-01

    The geomorphology and morphostratigraphy of numerous worldwide sites reveal the relative movements of sea level during the peak of the Last Interglaciation (Marine Isotope Stage (MIS) 5e, assumed average duration between 130±2 and 119±2 ka). Because sea level was higher than present, deposits are emergent, exposed, and widespread on many stable coastlines. Correlation with MIS 5e is facilitated by similar morphostratigraphic relationships, a low degree of diagenesis, uranium-thorium (U/Th) ages, and a global set of amino-acid racemization (AAR) data. This study integrates information from a large number of sites from tectonically stable areas including Bermuda, Bahamas, and Western Australia, and some that have experienced minor uplift (˜2.5 m/100 ka), including selected sites from the Mediterranean and Hawaii. Significant fluctuations during the highstand are evident at many MIS 5e sites, revealed from morphological, stratigraphic, and sedimentological evidence. Rounded and flat-topped curves derived only from reef tracts are incomplete and not representative of the entire interglacial story. Despite predictions of much different sea-level histories in Bermuda, the Bahamas, and Western Australia due to glacio- and hydro-isostatic effects, the rocks from these sites reveal a nearly identical record during the Last Interglaciation. The Last Interglacial highstand is characterized by several defined sea-level intervals (SLIs) that include: (SLI#1) post-glacial (MIS 6/5e Termination II) rise to above present before 130 ka; (SLI#2) stability at +2 to +3 m for the initial several thousand years (˜130 to ˜125 ka) during which fringing reefs were established and terrace morphology was imprinted along the coastlines; (SLI#3) a brief fall to near or below present around 125 ka; (SLI#4) a secondary rise to and through ˜+3-4 m (˜124 to ˜122 ka); followed by (SLI#5) a brief period of instability (˜120 ka) characterized by a rapid rise to between +6 to +9 m during

  19. Exceptional Agulhas leakage prolonged interglacial warmth during MIS 11c in Europe

    NASA Astrophysics Data System (ADS)

    Koutsodendris, Andreas; Pross, Jörg; Zahn, Rainer

    2014-11-01

    The transport of warm and saline surface water from the Indo-Pacific Ocean into the South Atlantic ("Agulhas leakage") influences the Atlantic Meridional Overturning Circulation (AMOC), which in turn exerts control on European climate. Paleoceanographic data document a remarkably strong Agulhas leakage at the end of marine isotope stage (MIS) 11c interglacial (~400 ka B.P.), which is one of the best orbital analogues for the Holocene. Here we assess the potential influence of this exceptional Agulhas leakage on North Atlantic climate based on a compilation of marine and terrestrial proxy records from the Iberian margin and continental Europe. We show that a ~5 ka long warm period persisted across Europe beyond the MIS 11c climatic optimum. This warm period is testified by increases in foraminifer-derived sea surface temperatures on the Iberian margin, a spread of temperate trees on Iberia, and the expansion both of evergreen trees and thermophilous diatom taxa in Central European lowlands. Paradoxically, this warming coincides with an insolation minimum, implying that orbital forcing can be excluded as the underlying cause. We conclude that persistent warmth during weak insolation at the end of MIS 11c in Europe may have been triggered by strengthened Agulhas leakage, which stimulated a vigorous AMOC and increased the northward transport of warm surface waters to higher latitudes via the North Atlantic Current. The close analogy of the present and MIS 11c orbital forcing underlines the possibility that the present-day increase of the Agulhas leakage, although driven by different forcing than MIS 11c, may considerably affect future climates across Europe.

  20. Orbital scale paleohydrological changes in the subtropical Mexico since MIS 5 and possible forcings

    NASA Astrophysics Data System (ADS)

    Quiroz-Jiménez, J. D.; Roy, P. D.; Lozano-SantaCruz, R.; Girón-García, P.; Sánchez Zavala, J. L.

    2015-12-01

    In Mexico, there are only two proxy records that provide information about the last interglacial. Lack of longer registers is a hindrance in understanding the effect of modern era global warming on the arid ecosystem of northern Mexico. We present a new orbital-scale record of hydrological changes occurred since the MIS 5 from the southern part of subtropical Mexico. This record is obtained from geochemistry of a 10 m long sediment core collected from central part of the Santiaguillo Basin. The age model is created with radiocarbon dates of sediments deposited over the last 27 cal ka and it incorporates a uniform sedimentation rate (calculated for the last 27 cal ka) for lower part of the core. Variation of runoff is reconstructed from Ti concentration and salinity of the water column is inferred from the abundance authigenic carbonates. Over the last 27 cal ka, this new record shows similar variations as that of our previous work done in sediment profiles collected from the littoral parts of the basin. We observe a first order positive correlation between the proxy records of runoff and lake water salinity with insolation values for the interpolated as well as the extrapolated parts of age model. The runoff record has orbital-scale similarities with autumn (September) insolation and variations in lake water salinity are comparable to summer (June) insolation. Santiaguillo Basin received more runoff (i.e. precipitation) during the intervals of higher autumn insolation and more carbonate deposition occurred (i.e. drought) during the intervals of higher summer insolation. During MIS 5, the hydrological variations were controlled by the insolation values. In general, MIS 4 and MIS 2 were intervals of more runoff and more carbonate deposition occurred during MIS 3. Comparison with other regional records suggests different geographic influences of NAM and Tropical Cyclones in orbital-scales.

  1. Ice Complex permafrost of MIS5 age in the Dmitry Laptev Strait coastal region (East Siberian Arctic)

    NASA Astrophysics Data System (ADS)

    Wetterich, Sebastian; Tumskoy, Vladimir; Rudaya, Natalia; Kuznetsov, Vladislav; Maksimov, Fedor; Opel, Thomas; Meyer, Hanno; Andreev, Andrei A.; Schirrmeister, Lutz

    2016-09-01

    Ice Complex deposits (locally known as the Buchchagy Ice Complex) are exposed at both coasts of the East Siberian Dmitry Laptev Strait and preserved below the Yedoma Ice Complex that formed during MIS3 and MIS2 (Marine Isotope Stage) and lateglacial-Holocene thermokarst deposits (MIS1). Radioisotope disequilibria (230Th/U) of peaty horizons date the Buchchagy Ice Complex deposition to 126 + 16/-13 kyr and 117 + 19/-14 kyr until 98 ± 5 kyr and 89 ± 5 kyr. The deposit is characterised by poorly-sorted medium-to-coarse silts with cryogenic structures of horizontal ice bands, lens-like, and lens-like reticulated segregation ice. Two peaty horizons within the Buchchagy Ice Complex and syngenetic ice wedges (2-4 m wide, up to 10 m high) are striking. The isotopic composition (δ18O, δD) of Buchchagy ice-wedge ice indicates winter conditions colder than during the MIS3 interstadial and warmer than during MIS2 stadial, and similar atmospheric winter moisture sources as during the MIS2 stadial. Buchchagy Ice Complex pollen spectra reveal tundra-steppe vegetation and harsher summer conditions than during the MIS3 interstadial and rather similar vegetation as during the MIS2 stadial. Short-term climatic variability during MIS5 is reflected in the record. Even though the regional chronostratigraphic relationship of the Buchchagy Ice Complex to the Last Interglacial remains unclear because numerical dating is widely lacking, the present study indicates permafrost (Ice Complex) formation during MIS5 sensu lato, and its preservation afterwards. Palaeoenvironmental insights into past climate and the periglacial landscape dynamics of arctic lowlands in eastern Siberia are deduced from the record.

  2. Model for the Establishment of Modern Atolls during the Mid Brunhes MIS 12 to MIS 11 Sea Level Transgression in the Maldive Archipelago (Equatorial Indian Ocean)

    NASA Astrophysics Data System (ADS)

    Droxler, A. W.; Belopolsky, A. V.

    2003-12-01

    The Maldive archipelago consists of 22 main atolls characterized by a marginal rim surrounding a lagoon commonly less than 50-60 m deep, though some lagoons reach depths of more than 80 m. The overall evolution of the carbonate system in the Maldive Archipelago clearly shows that the slow subsidence of hypothetical volcanic edifices buried under the atolls cannot explain their typical ringed morphology. On the contrary, the atolls in the Maldives, as most likely the majority of the modern atolls, are probably young (less than 0.5 My old) carbonate edifices. Our research in the Maldives was developed based upon the interpretation of two Elf-Aquitaine and Royal Dutch Shell MCS grids, groundtruthed by ODP Site 716 and two deep exploration wells. Several seismic profiles across the modern atoll margins clearly illustrate a shift from middle Miocene-early Pliocene sigmoid lateral margin progradation of flat-topped carbonate banks to late Quaternary bank top vertical aggradation evolving into the modern atoll physiography. This well-marked transition is first illustrated by a regionally observed initial downward shift of the depositional system dated at 3.0-2.5 Ma. This downward shift of onlap and subsequent deposition in sedimentary wedges below the early Pliocene bank margins are explained by a late Pliocene-early Pleistocene (3.0-0.5 My) gradual sea level regression tied to the onset and successive expansions of major continental ice sheets in the northern Hemisphere. This regression is clearly defined in several Pliocene-Quaternary high resolution benthic isotope records, best proxy for ice volume variations in the past 5 My, at ODP sites such as 659, 677, 846, and 849.The early Pliocene flat-topped carbonate banks, exposed for about 2.5 My in the late Pliocene and early Pleistocene, were fully re-flooded for the first time at the glacial MIS 12 to interglacial MIS 11 transition. This sea level transgression is unique by its highest amplitude among the multiple sea

  3. Minimally Invasive Direct Lateral Interbody Fusion (MIS-DLIF): Proof of Concept and Perioperative Results

    PubMed Central

    Abbasi, Hamid

    2017-01-01

    Background Minimally invasive direct lateral interbody fusion (MIS-DLIF) is a novel approach for fusions of the lumbar spine. In this proof of concept study, we describe the surgical technique and report our experience and the perioperative outcomes of the first nine patients who underwent this procedure. Study design/setting In this study we establish the safety and efficacy of this approach. MIS-DLIF was performed on 15 spinal levels in nine patients who failed to respond to conservative therapy for the treatment of a re-herniated disk, spondylolisthesis, or other severe disk disease of the lumbar spine. We recorded surgery time, blood loss, fluoroscopy time, patient-reported pain, and complications. Methods Throughout the MIS-DLIF procedure, the surgeon is aided by biplanar fluoroscopic imaging to place an interbody graft or cage into the disc space through the interpleural space. A discectomy is performed in the same minimally invasive fashion. The procedure is usually completed with posterior pedicle screw fixation. Results MIS-DLIF took 44/85 minutes, on average, for 1/2 levels, with 54/112 ml of blood loss, and 0.3/1.7 days of hospital stay. Four of nine patients did not require overnight hospitalization and were discharged two to four hours after surgery. We did not encounter any clinically significant complications. At more than ninety days post surgery, the patients reported a statistically significant reduction of 4.5 points on a 10-point sliding pain scale. Conclusions MIS-DLIF with pedicle screw fixation is a safe and clinically effective procedure for fusions of the lumbar spine. The procedure overcomes many of the limitations of the current minimally invasive approaches to the lumbar spine and is technically straightforward. MIS-DLIF has the potential to improve patient outcomes and reduce costs relative to the current standard of care and therefore warrants further investigation. We are currently expanding this study to a larger cohort and

  4. 49 CFR 40.26 - What form must an employer use to report Management Information System (MIS) data to a DOT agency?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Management Information System (MIS) data to a DOT agency? 40.26 Section 40.26 Transportation Office of the... Employer Responsibilities § 40.26 What form must an employer use to report Management Information System (MIS) data to a DOT agency? As an employer, when you are required to report MIS data to a DOT...

  5. 49 CFR 40.26 - What form must an employer use to report Management Information System (MIS) data to a DOT agency?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Management Information System (MIS) data to a DOT agency? 40.26 Section 40.26 Transportation Office of the... Employer Responsibilities § 40.26 What form must an employer use to report Management Information System (MIS) data to a DOT agency? As an employer, when you are required to report MIS data to a DOT...

  6. 49 CFR 40.26 - What form must an employer use to report Management Information System (MIS) data to a DOT agency?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Management Information System (MIS) data to a DOT agency? 40.26 Section 40.26 Transportation Office of the... Employer Responsibilities § 40.26 What form must an employer use to report Management Information System (MIS) data to a DOT agency? As an employer, when you are required to report MIS data to a DOT...

  7. 49 CFR 40.26 - What form must an employer use to report Management Information System (MIS) data to a DOT agency?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Management Information System (MIS) data to a DOT agency? 40.26 Section 40.26 Transportation Office of the... Employer Responsibilities § 40.26 What form must an employer use to report Management Information System (MIS) data to a DOT agency? As an employer, when you are required to report MIS data to a DOT...

  8. 49 CFR 40.26 - What form must an employer use to report Management Information System (MIS) data to a DOT agency?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Management Information System (MIS) data to a DOT agency? 40.26 Section 40.26 Transportation Office of the... Employer Responsibilities § 40.26 What form must an employer use to report Management Information System (MIS) data to a DOT agency? As an employer, when you are required to report MIS data to a DOT...

  9. Short- and long-term effects of chromosome mis-segregation and aneuploidy.

    PubMed

    Santaguida, Stefano; Amon, Angelika

    2015-08-01

    Dividing cells that experience chromosome mis-segregation generate aneuploid daughter cells, which contain an incorrect number of chromosomes. Although aneuploidy interferes with the proliferation of untransformed cells, it is also, paradoxically, a hallmark of cancer, a disease defined by increased proliferative potential. These contradictory effects are also observed in mouse models of chromosome instability (CIN). CIN can inhibit and promote tumorigenesis. Recent work has provided insights into the cellular consequences of CIN and aneuploidy. Chromosome mis-segregation per se can alter the genome in many more ways than just causing the gain or loss of chromosomes. The short- and long-term effects of aneuploidy are caused by gene-specific effects and a stereotypic aneuploidy stress response. Importantly, these recent findings provide insights into the role of aneuploidy in tumorigenesis.

  10. Modelling and extraction procedure for gate insulator and fringing gate capacitance components of an MIS structure

    NASA Astrophysics Data System (ADS)

    Tinoco, J. C.; Martinez-Lopez, A. G.; Lezama, G.; Mendoza-Barrera, C.; Cerdeira, A.; Estrada, M.

    2016-07-01

    CMOS technology has been guided by the continuous reduction of MOS transistors used to fabricate integrated circuits. Additionally, the use of high-k dielectrics as well as a metal gate electrode have promoted the development of nanometric MOS transistors. Under this scenario, the proper modelling of the gate capacitance, with the aim of adequately evaluating the dielectric film thickness, becomes challenging for nanometric metal-insulator-semiconductor (MIS) structures due to the presence of extrinsic fringing capacitance components which affect the total gate capacitance. In this contribution, a complete intrinsic-extrinsic model for gate capacitance under accumulation of an MIS structure, together with an extraction procedure in order to independently determine the different capacitance components, is presented. ATLAS finite element simulation has been used to validate the proposed methodology.

  11. Basic mechanisms study for MIS solar cell structures on GaAs

    NASA Technical Reports Server (NTRS)

    Fonash, S. J.

    1978-01-01

    The solar cell structure examined is the MIS configuration on (n) GaAs. The metal room temperature oxide/(n) GaAs materials system was studied. Metals with electronegativities varying from 2.4 (Au) to 1.5 (Al) were used as the upper electrode. The thinnest metallization that did not interfere with the measurement techniques (by introducing essentially transmission line series resistance problems across a device) was used. Photovoltaic response was not optimized.

  12. Automated software development tools in the MIS (Management Information Systems) environment

    SciTech Connect

    Arrowood, L.F.; Emrich, M.L.

    1987-09-11

    Quantitative and qualitative benefits can be obtained through the use of automated software development tools. Such tools are best utilized when they complement existing procedures and standards. They can assist systems analysts and programmers with project specification, design, implementation, testing, and documentation. Commercial products have been evaluated to determine their efficacy. User comments have been included to illustrate actual benefits derived from introducing these tools into MIS organizations.

  13. Extensive MIS 3 glaciation in southernmost Patagonia revealed by cosmogenic nuclide dating of outwash sediments

    NASA Astrophysics Data System (ADS)

    Darvill, Christopher M.; Bentley, Michael J.; Stokes, Chris R.; Hein, Andrew S.; Rodés, Ángel

    2015-11-01

    The timing and extent of former glacial advances can demonstrate leads and lags during periods of climatic change and their forcing, but this requires robust glacial chronologies. In parts of southernmost Patagonia, dating pre-global Last Glacial Maximum (gLGM) ice limits has proven difficult due to post-deposition processes affecting the build-up of cosmogenic nuclides in moraine boulders. Here we provide ages for the Río Cullen and San Sebastián glacial limits of the former Bahía Inútil-San Sebastián (BI-SSb) ice lobe on Tierra del Fuego (53-54°S), previously hypothesised to represent advances during Marine Isotope Stages (MIS) 12 and 10, respectively. Our approach uses cosmogenic 10Be and 26Al exposure dating, but targets glacial outwash associated with these limits and uses depth-profiles and surface cobble samples, thereby accounting for surface deflation and inheritance. The data reveal that the limits formed more recently than previously thought, giving ages of 45.6 ka (+139.9/-14.3) for the Río Cullen, and 30.1 ka (+45.6/-23.1) for the San Sebastián limits. These dates indicate extensive glaciation in southern Patagonia during MIS 3, prior to the well-constrained, but much less extensive MIS 2 (gLGM) limit. This suggests the pattern of ice advances in the region was different to northern Patagonia, with the terrestrial limits relating to the last glacial cycle, rather than progressively less extensive glaciations over hundreds of thousands of years. However, the dates are consistent with MIS 3 glaciation elsewhere in the southern mid-latitudes, and the combination of cooler summers and warmer winters with increased precipitation, may have caused extensive glaciation prior to the gLGM.

  14. The "MIS 11 paradox" and ocean circulation: Role of millennial scale events

    NASA Astrophysics Data System (ADS)

    Vázquez Riveiros, Natalia; Waelbroeck, Claire; Skinner, Luke; Duplessy, Jean-Claude; McManus, Jerry F.; Kandiano, Evgenia S.; Bauch, Henning A.

    2013-06-01

    The role of millennial scale climate variability in supplementing the astronomical forcing of glacial-interglacial transitions remains a major unresolved question. Here we compare the occurrence and character of "terminal" ice rafting events in both the North and South Atlantic during the last deglaciation (Termination I, TI) and during the transition between Marine Isotope Stages (MIS) 12 and 11 (or Termination V, TV). We show that TV experienced a massive terminal ice rafting event in the North Atlantic that was more intense and longer lasting than Heinrich event 1 (H1) of the last deglaciation. This massive ice rafting event was linked to cold stadial conditions and reduced deep water formation in the North Atlantic, in parallel with warming at high southern latitudes, similar to the bipolar seesaw pattern exhibited during H1 over the last deglaciation. We propose that the particular intensity and duration of the TV ice rafting event resulted from the especially large volume of Northern Hemisphere ice sheets during MIS12. In turn, the unusually long duration and large amplitude of TV likely resulted from the exceptionally prolonged collapse of the AMOC during the TV Heinrich stadial, and from a subsequent transient AMOC "overshoot" with respect to later MIS11 interglacial circulation. Furthermore, we suggest that the intense Heinrich stadial of TV contributed to the deglaciation primarily via meridional heat transport anomalies that would have enhanced the incipient warming arising from relatively weak insolation forcing, and only secondarily via CO2 release.

  15. Duodenal Atresia: Open versus MIS Repair—Analysis of Our Experience over the Last 12 Years

    PubMed Central

    Bucci, Valeria; Conighi, Maria Luisa; Zolpi, Elisa; Costa, Lorenzo; Fasoli, Lorella

    2017-01-01

    Objective. Duodenal atresia (DA) routinely has been corrected by laparotomy and duodenoduodenostomy with excellent long-term results. We revisited the patients with DA treated in the last 12 years (2004–2016) comparing the open and the minimally invasive surgical (MIS) approach. Methods. We divided our cohort of patients into two groups. Group 1 included 10 patients with CDO (2004–09) treated with open procedure: 5, DA; 3, duodenal web; 2, extrinsic obstruction. Three presented with Down's syndrome while 3 presented with concomitant malformations. Group 2 included 8 patients (2009–16): 1, web; 5, DA; 2, extrinsic obstruction. Seven were treated by MIS; 1 was treated by Endoscopy. Three presented with Down's syndrome; 3 presented with concomitant malformations. Results. Average operating time was 120 minutes in Group 1 and 190 minutes in Group 2. In MIS Group the visualization was excellent. We recorded no intraoperative complications, conversions, or anastomotic leakage. Feedings started on 3–7 postoperative days. Follow-up showed no evidence of stricture or obstruction. In Group 1 feedings started within 10–22 days and we have 1 postoperative obstruction. Conclusions. Laparoscopic repair of DA is one of the most challenging procedures among pediatric laparoscopic procedures. These patients had a shorter length of hospitalization and more rapid advancement to full feeding compared to patients undergoing the open approach. Laparoscopic repair of DA could be the preferred technique, safe, and efficacious, in the hands of experienced surgeons. PMID:28326320

  16. Chromosome mis-segregation and cytokinesis failure in trisomic human cells.

    PubMed

    Nicholson, Joshua M; Macedo, Joana C; Mattingly, Aaron J; Wangsa, Darawalee; Camps, Jordi; Lima, Vera; Gomes, Ana M; Dória, Sofia; Ried, Thomas; Logarinho, Elsa; Cimini, Daniela

    2015-05-05

    Cancer cells display aneuploid karyotypes and typically mis-segregate chromosomes at high rates, a phenotype referred to as chromosomal instability (CIN). To test the effects of aneuploidy on chromosome segregation and other mitotic phenotypes we used the colorectal cancer cell line DLD1 (2n = 46) and two variants with trisomy 7 or 13 (DLD1+7 and DLD1+13), as well as euploid and trisomy 13 amniocytes (AF and AF+13). We found that trisomic cells displayed higher rates of chromosome mis-segregation compared to their euploid counterparts. Furthermore, cells with trisomy 13 displayed a distinctive cytokinesis failure phenotype. We showed that up-regulation of SPG20 expression, brought about by trisomy 13 in DLD1+13 and AF+13 cells, is sufficient for the cytokinesis failure phenotype. Overall, our study shows that aneuploidy can induce chromosome mis-segregation. Moreover, we identified a trisomy 13-specific mitotic phenotype that is driven by up-regulation of a gene encoded on the aneuploid chromosome.

  17. Response of the North Atlantic surface and intermediate ocean structure to climate warming of MIS 11

    PubMed Central

    Kandiano, Evgenia S.; van der Meer, Marcel T. J.; Schouten, Stefan; Fahl, Kirsten; Sinninghe Damsté, Jaap S.; Bauch, Henning A.

    2017-01-01

    Investigating past interglacial climates not only help to understand how the climate system operates in general, it also forms a vital basis for climate predictions. We reconstructed vertical stratification changes in temperature and salinity in the North Atlantic for a period some 400 ka ago (MIS11), an interglacial time analogue of a future climate. As inferred from a unique set of biogeochemical, geochemical, and faunal data, the internal upper ocean stratification across MIS 11 shows distinct depth-dependent dynamical changes related to vertical as well as lateral shifts in the upper Atlantic meridional circulation system. Importantly, transient cold events are recognized near the end of the long phase of postglacial warming at surface, subsurface, mid, and deeper water layers. These data demonstrate that MIS 11 coolings over the North Atlantic were initially triggered by freshwater input at the surface and expansion of cold polar waters into the Subpolar Gyre. The cooling signal was then transmitted downwards into mid-water depths. Since the cold events occurred after the main deglacial phase we suggest that their cause might be related to continuous melting of the Greenland ice sheet, a mechanism that might also be relevant for the present and upcoming climate. PMID:28393849

  18. Pathological impact of SMN2 mis-splicing in adult SMA mice.

    PubMed

    Sahashi, Kentaro; Ling, Karen K Y; Hua, Yimin; Wilkinson, John Erby; Nomakuchi, Tomoki; Rigo, Frank; Hung, Gene; Xu, David; Jiang, Ya-Ping; Lin, Richard Z; Ko, Chien-Ping; Bennett, C Frank; Krainer, Adrian R

    2013-10-01

    Loss-of-function mutations in SMN1 cause spinal muscular atrophy (SMA), a leading genetic cause of infant mortality. The related SMN2 gene expresses suboptimal levels of functional SMN protein, due to a splicing defect. Many SMA patients reach adulthood, and there is also adult-onset (type IV) SMA. There is currently no animal model for adult-onset SMA, and the tissue-specific pathogenesis of post-developmental SMN deficiency remains elusive. Here, we use an antisense oligonucleotide (ASO) to exacerbate SMN2 mis-splicing. Intracerebroventricular ASO injection in adult SMN2-transgenic mice phenocopies key aspects of adult-onset SMA, including delayed-onset motor dysfunction and relevant histopathological features. SMN2 mis-splicing increases during late-stage disease, likely accelerating disease progression. Systemic ASO injection in adult mice causes peripheral SMN2 mis-splicing and affects prognosis, eliciting marked liver and heart pathologies, with decreased IGF1 levels. ASO dose-response and time-course studies suggest that only moderate SMN levels are required in the adult central nervous system, and treatment with a splicing-correcting ASO shows a broad therapeutic time window. We describe distinctive pathological features of adult-onset and early-onset SMA.

  19. Minimizing and quantifying mis-indexing in electron backscatter diffraction (EBSD) determinations of antigorite crystal directions

    NASA Astrophysics Data System (ADS)

    Nagaya, Takayoshi; Wallis, Simon R.; Seto, Yusuke; Miyake, Akira; Soda, Yusuke; Uehara, Seiichiro; Matsumoto, Megumi

    2017-02-01

    Antigorite is common in hydrated mantle domains and commonly shows strong alignment either due to deformation or growth in a preferred orientation. The alignment of antigorite imparts a strong anisotropy to the host rock affecting physical properties. A quantitative analysis of how antigorite affects these properties requires a reliable measurement of the crystallographic preferred orientation of antigorite, and EBSD analysis is the most widely used technique. Potential problems include (i) mis-indexing, which can add significant uncertainties to the results; and (ii) sample preparation, which may affect the measured CPO in particular for automated mapping. Combining results derived from X-ray goniometry, EBSD and U-stage techniques with FIB-TEM analysis leads to the following conclusions concerning these two issues. (i) There is a significant issue with mis-indexing a- and b-axes due to rotational similarities about the c-axis. Similar problems may also affect the c-axes measurements but this is less significant than the a- and b-axes when data are filtered using lower MAD values. Filtering using MAD values of <0.7° can significantly change the resulting CPO. (ii) Sample preparation can also affect the measured CPO: sections prepared parallel to the foliation show only minor differences with MAD values of <2.0°. Mis-indexing problems can be minimized by using an MAD value of <0.7° and analysing thin sections cut parallel to the foliation.

  20. Transfer RNA: a dancer between charging and mis-charging for protein biosynthesis.

    PubMed

    Zhou, Xiaolong; Wang, Enduo

    2013-10-01

    Transfer RNA plays a fundamental role in the protein biosynthesis as an adaptor molecule by functioning as a biological link between the genetic nucleotide sequence in the mRNA and the amino acid sequence in the protein. To perform its role in protein biosynthesis, it has to be accurately recognized by aminoacyl-tRNA synthetases (aaRSs) to generate aminoacyl-tRNAs (aa-tRNAs). The correct pairing between an amino acid with its cognate tRNA is crucial for translational quality control. Production and utilization of mis-charged tRNAs are usually detrimental for all the species, resulting in cellular dysfunctions. Correct aa-tRNAs formation is collectively controlled by aaRSs with distinct mechanisms and/or other trans-factors. However, in very limited instances, mis-charged tRNAs are intermediate for specific pathways or essential components for the translational machinery. Here, from the point of accuracy in tRNA charging, we review our understanding about the mechanism ensuring correct aa-tRNA generation. In addition, some unique mis-charged tRNA species necessary for the organism are also briefly described.

  1. A Pleistocene (MIS 5e) mollusk assemblage from Ezeiza (Buenos Aires Province, Argentina)

    NASA Astrophysics Data System (ADS)

    Martínez, Sergio; Julia del Río, Claudia; Rojas, Alejandra

    2016-10-01

    A fossil assemblage collected around 3.5 m amsl from Ezeiza, Buenos Aires province, have AMS 14C ages of ca. 33,000 to ca. 40,000 yr BP, whereas in the literature is a report of a conventional 14C age of >43,000 yr BP. An OSL age from the overlying deposit corresponds to ca. 22,000 yr. The samples contain marine fossils: mollusks, balanids and corals (Astrangia). La Coronilla (Uruguay, attributed to MIS 5e) is the locality most related to Ezeiza faunistically, despite is not the nearest one. In consequence, the relationship should be addressed to a more similar age and environment than others. The fauna indicates a higher water temperature than today. In Ezeiza exclusively cold water taxa are absent, and we found seven warm taxa with their southern distribution limit displaced northwards today, plus other six at their southern distribution limit. Around 60% of all the species and more than 70% of the individuals are of warm-temperate waters. In sum, although prima facie the numerical ages would locate the deposit in MIS3, faunistic, temperature, and height evidences show that the Ezeiza mollusk assemblage belong to MIS5e. A stronger than presently Brazil warm current, reaching Southern latitudes, may explain the changes in geographical ranges.

  2. Chronology and stratigraphy for the MIS 2 damming of glacial Lake Wisconsin, USA

    NASA Astrophysics Data System (ADS)

    Carson, E. C.; Attig, J. W.; Rawling, J. E., III

    2015-12-01

    Glacial Lake Wisconsin formed during the Marine Isotope Stage (MIS) 2 glaciation when the Green Bay Lobe (GBL) of the Laurentide Ice Sheet dammed the Wisconsin River at the Baraboo Hills in south-central Wisconsin. Despite nearly a century of research, the precise chronology for the Green Bay Lobe's advance to and retreat from its maximum position, and the resulting damming and subsequent drainage of glacial Lake Wisconsin, remains unsettled (e.g., Colgan, 1992; Attig et al., 2011; Ullman et al., 2014). Age estimates from core collected in ice-proximal lacustrine sediment beyond the glacial margin provide chronologic constraint for ice margin fluctuations that controlled glacial Lake Wisconsin's formation and drainage. Additional cores collected in glacial sediment at and behind the MIS 2 ice margin provide stratigraphic evidence for the dynamics of the GBL during the end of advance to, and the start of retreat from, the MIS 2 maximum. The combined data from these cores suggest that glacial Lake Wisconsin may have filled only once to its highest stage during the MIS 2 maximum, after ice blocked both the east end of the Baraboo Hills and the south end of the Devils Lake gorge. When the ice reached its maximum position and blocked the north end of the gorge, Devils Lake was isolated from glacial Lake Wisconsin and rose to a higher level. Radiocarbon and OSL ages from the Devils Lake gorge indicate that the GBL advanced to the MIS 2 maximum position by 24.6 ka, and remained at or near that location through 19.2 ± 3.2 ka. Radiocarbon ages from lacustrine sediment in a sub-basin of glacial Lake Wisconsin indicate that ice continued to block the Wisconsin River between 21.6 ka and 17.4 ka. The stratigraphy evident in cores at the Devils Lake gorge and south of the Baraboo Hills indicates that ice thinned and advanced immediately prior to retreat, likely in response to reduced basal shear stress as the bed of the glacier thawed.

  3. Last Interglacial (MIS5e) hydrographic shifts linked to meltwater discharges from the East Greenland margin

    NASA Astrophysics Data System (ADS)

    Zhuravleva, Anastasia; Bauch, Henning A.; Van Nieuwenhove, Nicolas

    2016-04-01

    The East Greenland Current (EGC) plays a key role in transporting polar water from the Arctic to convectional sites of the Iceland and Labrador seas. Ongoing melting of the Greenland Ice Sheet (GIS) as well as the Arctic sea ice prompts freshening of the EGC and accumulation of low-density water in the subpolar North Atlantic, thus affecting the stabilities of water mass overturning and subsequent northward heat transfer. To assess natural eastern GIS dynamics and possible freshwater-induced regional oceanic reorganizations we analyzed several sediment sequences from the poorly investigated area along the eastern Greenland margin and the western Nordic Seas. Records span the last interglacial (LIG, MIS5e) cycle, including deglacial Termination 2 and the LIG climatic optimum. On a global scale, the latter is believed to have been warmer than present, with a higher sea level, and may, therefore, serve as a promising analogue for future hydrographic changes. Based on various proxy data (stable isotopes, planktic foraminiferal assemblages, ice-rafted debris) our reconstructions support the notion of a "two-step development" of Termination 2 which underwent severe surface freshening in the subpolar North Atlantic. This is shown in extremely light oxygen isotopic values registered all along the eastern Greenland margin during early MIS5e, which are indicative for pronounced eastern/central GIS retreat and a further propagation of the resulting meltwater southward via the EGC. In addition, we find compelling evidence for at least two separate meltwater episodes in proximity of the eastern GIS during early MIS5e. The climatic episode in between is correlated with an early LIG warm peak, which may be linked to enhanced presence of Atlantic water in the central Nordic Seas (Bauch et al., 2012) and further downstream along southern Greenland (Hillaire-Marcel et al., 1994, Irvali et al., 2012). Our data, therefore, reveal a complex and variable dynamic of the EGC during MIS5e

  4. The MisR Response Regulator Is Necessary for Intrinsic Cationic Antimicrobial Peptide and Aminoglycoside Resistance in Neisseria gonorrhoeae

    PubMed Central

    Kandler, Justin L.; Holley, Concerta L.; Reimche, Jennifer L.; Dhulipala, Vijaya; Balthazar, Jacqueline T.; Muszyński, Artur; Carlson, Russell W.

    2016-01-01

    During infection, the sexually transmitted pathogen Neisseria gonorrhoeae (the gonococcus) encounters numerous host-derived antimicrobials, including cationic antimicrobial peptides (CAMPs) produced by epithelial and phagocytic cells. CAMPs have both direct and indirect killing mechanisms and help link the innate and adaptive immune responses during infection. Gonococcal CAMP resistance is likely important for avoidance of host nonoxidative killing systems expressed by polymorphonuclear granulocytes (e.g., neutrophils) and intracellular survival. Previously studied gonococcal CAMP resistance mechanisms include modification of lipid A with phosphoethanolamine by LptA and export of CAMPs by the MtrCDE efflux pump. In the related pathogen Neisseria meningitidis, a two-component regulatory system (2CRS) termed MisR-MisS has been shown to contribute to the capacity of the meningococcus to resist CAMP killing. We report that the gonococcal MisR response regulator but not the MisS sensor kinase is involved in constitutive and inducible CAMP resistance and is also required for intrinsic low-level resistance to aminoglycosides. The 4- to 8-fold increased susceptibility of misR-deficient gonococci to CAMPs and aminoglycosides was independent of phosphoethanolamine decoration of lipid A and the levels of the MtrCDE efflux pump and seemed to correlate with a general increase in membrane permeability. Transcriptional profiling and biochemical studies confirmed that expression of lptA and mtrCDE was not impacted by the loss of MisR. However, several genes encoding proteins involved in membrane integrity and redox control gave evidence of being MisR regulated. We propose that MisR modulates the levels of gonococcal susceptibility to antimicrobials by influencing the expression of genes involved in determining membrane integrity. PMID:27216061

  5. CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading

    PubMed Central

    Pan, Dongqing; Klare, Kerstin; Petrovic, Arsen; Take, Annika; Walstein, Kai; Singh, Priyanka; Rondelet, Arnaud; Bird, Alexander W; Musacchio, Andrea

    2017-01-01

    Centromeres are unique chromosomal loci that promote the assembly of kinetochores, macromolecular complexes that bind spindle microtubules during mitosis. In most organisms, centromeres lack defined genetic features. Rather, they are specified epigenetically by a centromere-specific histone H3 variant, CENP-A. The Mis18 complex, comprising the Mis18α:Mis18β subcomplex and M18BP1, is crucial for CENP-A homeostasis. It recruits the CENP-A-specific chaperone HJURP to centromeres and primes it for CENP-A loading. We report here that a specific arrangement of Yippee domains in a human Mis18α:Mis18β 4:2 hexamer binds two copies of M18BP1 through M18BP1’s 140 N-terminal residues. Phosphorylation by Cyclin-dependent kinase 1 (CDK1) at two conserved sites in this region destabilizes binding to Mis18α:Mis18β, limiting complex formation to the G1 phase of the cell cycle. Using an improved viral 2A peptide co-expression strategy, we demonstrate that CDK1 controls Mis18 complex recruitment to centromeres by regulating oligomerization of M18BP1 through the Mis18α:Mis18β scaffold. DOI: http://dx.doi.org/10.7554/eLife.23352.001 PMID:28059702

  6. Outcome Measures of an Intracanal, Endoscopic Transforaminal Decompression Technique: Initial Findings from the MIS Prospective Registry

    PubMed Central

    Sclafani, Joseph A.; Raiszadeh, Kamshad; Laich, Dan; Shen, Jian; Bennett, Matthew; Blok, Robert; Liang, Kevin

    2015-01-01

    Background Minimally invasive transforaminal endoscopic procedures can achieve spinal decompression through either direct or indirect techniques. Subtle variations in trajectory of the surgical corridor can dictate access to the pathologic tissue. Two general strategies exist: the intradiscal “inside-out” technique and the extradiscal, intracanal (IC) technique. The IC technique utilizes a more lateral transforaminal approach than the intradiscal technique, which allows for a more direct decompression of the spinal canal. Objective This study is an assessment of IC patient outcome data obtained through analysis of a previously validated MIS Prospective Registry. Methods Post-hoc analysis was performed on the MIS Prospective Registry database containing 1032 patients. A subgroup of patients treated with the endoscopic IC technique was identified. Patient outcome measures after treatment of symptomatic disk herniation and neuroforaminal stenosis were evaluated. Results A total of 86 IC patients were analyzed. Overall, there was significant improvement in employment and walking tolerance as soon as 6 weeks post-op as well as significant one year VAS and ODI score improvement. Subanalysis of IC patients with two distinct primary diagnoses was performed. Group IC-1 (disc herniation) showed improvement in ODI and VAS back and leg outcomes at 1 year post-op. Group IC-2 (foraminal stenosis) showed VAS back and leg score improvement at one year post-op but did not demonstrate significant improvement in overall ODI outcome at any time point. The one year re-operation rate was 2% (1/40) for group IC-1 and 28% (5/18) for group IC-2. Conclusions The initial results of the MIS Registry IC subgroup show a significant clinical improvement when the technique is employed to treat patients with lumbar disc herniation. The treatment of foraminal stenosis can lead to improved short-term clinical outcome but is associated with a high re-operation rate at 1 year post-op. PMID

  7. Coastal response to climate change: Mediterranean shorelines during the Last Interglacial (MIS 5)

    NASA Astrophysics Data System (ADS)

    Mauz, Barbara; Fanelli, Fabio; Elmejdoub, Noureddine; Barbieri, Roberto

    2012-10-01

    The response of shorelines to climate change is controlled by fall and rise of the sea level and by the alteration of the coastal environment due to changing fluvial discharge and biological activity. In the Mediterranean this response is complicated by the geographic proximity of the North Atlantic and the African Monsoon climate systems, by a time and space specific interaction of eustatic and water-load components of sea level and by the mid-latitudinal time lag between orbital forcing and terrestrial response. Here, six Mediterranean coastal records are presented which contribute to our understanding of how mid-latitudinal coasts respond to orbital forcing. The sediment sequences show sharp switches between siliciclastic- and carbonate-dominated nearshore environments where carbonate-rich sediments are composed of oolitic grainstones. From modern analogues it is deduced that the oolitic sediments represent a period of relatively high annual sea-surface temperature and lack of fluvial discharge. The warm-arid period was recorded at ˜114 ka on the southeast Iberian coast, at ˜113 ka on the Levant coast, at ˜110 ka on the coast west of the Nile delta and at ˜83 ka on the north Saharan coast. It lasted 10-20 ka in east (Levant coast) and west (Iberian coast) and lasted 40 ka or more in the central-south of the east Mediterranean. Timing and duration of the coastal proxy allow inferring instantaneous and dominant response to external forcing in the east and west and delayed and prolonged response due to dominant regional forcing in the centre of the East Mediterranean. A 9 m eustatic sea-level highstand during MIS 5e is suggested with a start of the subsequent sea-level fall at ˜118 ka while evidence for multiple MIS 5e highstand and a highstand during MIS 5a remain elusive.

  8. Bench-scale simulation of quenching and stabilization of MIS retorts

    SciTech Connect

    Barbour, F.A.; Boysen, J.E.

    1992-06-01

    This research was conducted to evaluate in situ retort stabilization methods. The objective of the bench-scale simulations was to evaluate possible post-retorting operating procedures for the optimum cleaning of spent retorts. After simulating conditions of modified in situ (MIS) retorts at the time retorting had ended, procedures to accelerate retort cleanup without using large volumes of water were investigated. Samples from various levels of the retort were used to determine the amount of water-soluble constituents in the spent shale and the rehydration characteristics of the spent shale.

  9. Bench-scale simulation of quenching and stabilization of MIS retorts

    SciTech Connect

    Barbour, F.A. ); Boysen, J.E. )

    1992-01-01

    This research was conducted to evaluate in situ retort stabilization methods. The objective of the bench-scale simulations was to evaluate possible post-retorting operating procedures for the optimum cleaning of spent retorts. After simulating conditions of modified in situ (MIS) retorts at the time retorting had ended, procedures to accelerate retort cleanup without using large volumes of water were investigated. Samples from various levels of the retort were used to determine the amount of water-soluble constituents in the spent shale and the rehydration characteristics of the spent shale.

  10. Space Station Furnace Facility Management Information System (SSFF-MIS) Development

    NASA Technical Reports Server (NTRS)

    Meade, Robert M.

    1996-01-01

    This report summarizes the chronology, results, and lessons learned from the development of the SSFF-MIS. This system has been nearly two years in development and has yielded some valuable insights into specialized MIS development. General: In December of 1994, the Camber Corporation and Science Applications International Corporation (SAIC) were contracted to design, develop, and implement a MIS for Marshall Space Flight Center's Space Station Furnace Facility Project. The system was to be accessible from both EBM-Compatible PC and Macintosh platforms. The system was required to contain data manually entered into the MIS as well as data imported from other MSFC sources. Electronic interfaces were established for each data source and retrieval was to be performed at prescribed time intervals. The SOW requirement that predominantly drove the development software selection was the dual-platform (IBM-PC and Macintosh) requirement. The requirement that the system would be maintained by Government personnel influenced the selection of Commercial Off-the-shelf software because of its inherent stability and readily available documentation and support. Microsoft FoxPro Professional 2.6 for Windows and Macintosh was selected as the development tool. This is a software development tool that has been in use for many years. It is stable and powerful. Microsoft has since released the replacement for this product, Microsoft Visual FoxPro, but at the time of this development, it was only available on the Windows platform. The initial contract included included the requirement for capabilities relating to the Work- and Organizational Breakdown Structures, cost (plan and actuals), workforce (plan and actuals), critical path scheduling, trend analysis, procurements and contracts, interface to manufacturing, Safety and Mission Assurance, risk analysis, and technical performance indicators. It also required full documentation of the system and training of users. During the course of

  11. Th-230 Dates of MIS 5e Coral Terraces in Kisar Island, Eastern Indonesia

    NASA Astrophysics Data System (ADS)

    Chiang, H. W.; Harris, R. A.; Prasetyadi, C.; Shen, C. C.; Chiu, T. C.; Cox, N. L.; Chen, Y. G.

    2010-05-01

    2004 Sumatra earthquakes caused a devastating tsunami and cost the lives of nearly 260,000 people in the South Asian region. These earthquakes and associated tsunami are sourced from convergence of the Indo-Australian and Asian Plates. In the eastern part of this plate boundary the Australian continent is colliding with Asia. The first turbiditic sand in Timor island was around 5 Ma and the collision propagated to the southwestern until ~2 Ma. But the activities of the neighborhood of the Timor island in the Quaternary or the Holocene is unknown. This study provides the new 230Th dates from the raised coral terraces at Kisar Island, eastern Indonesia. Eight fossil corals were measured by MC-ICP-MS at the National Taiwan University with permil-level precision. Two out of the eight samples having ~1.5 % calcite and acceptable δ234Uinitial showed robust ages of 123-121 ka. Another three open-system model ages were from 125-119 ka by Thompson et al.'s method (2003). These different elevated fossil corals with ages of 125-119 ka favored the two-peak sea-level curve in MIS 5e explained by Chappell and Veeh (1978). New age results relocated the second peak should be about three thousand years earlier than their proposed 119 ka. A minimum uplift rate of 0.1 m/kyrs is derived from the highest-position fossil corals. The 230Th-dated fossils in the north coast of Timor-Leste suggest the MIS 5e terraces could reach 55 m high, hence a referable uplift rate of ~0.4 m/kyrs could be a maximum estimate. The uplift rate of 0.1-0.4 m/ka since late Pleistocene is well consistent with published values from Atauro Island and Timor-Leste in eastern Indonesia. Based on the uplift rate, the terraces in eastern Kisar, with elevation lower than 100 m, expectedly located at MIS 7, 9, or 11; while the higher western terraces ranged from MIS 9-15. Besides, no remanet of Holocene fringe reefs around Kisar Island also suggests a relatively low activity of tectonics, in agreement with the modern

  12. Insights into North Atlantic deep water formation during the peak interglacial interval of Marine Isotope Stage 9 (MIS 9)

    NASA Astrophysics Data System (ADS)

    Mokeddem, Zohra; McManus, Jerry F.

    2017-01-01

    Foraminifera abundance and stable isotope records from ODP Site 984 (61.25°N, 24.04°W, 1648 m) in the North Atlantic are used to reconstruct surface circulation variations and the relative strength of the North Atlantic Deep Water (NADW) formation over the period spanning the peak warmth of Marine Interglacial Stage (MIS) 9e ( 324-336 ka). This interval includes the preceding deglaciation, Termination 4 (T4), and the subsequent glacial inception of MIS 9d. The records indicate a greatly reduced contribution of NADW during T4, as observed in more recent deglaciations. In contrast with the most recent deglaciation, the lack of a significant NADW signal extended from T4 well into the peak interglacial MIS 9e and persisted nearly until the transition to the subsequent glacial stage MIS 9d. Although NADW formation resumed during MIS 9e, only depths greater than 2000 m appear to have been ventilated. The poorly ventilated intermediate depth of Site 984 (<2000 m) may have resulted on one hand from a general reduction of deep water ventilation by NADW during the study interval or, on the other hand, from different pathways of the spread of newly formed NADW that bypassed the study location. The intermediate depths may have also been invaded by southern-sourced waters as the formation of intermediate depth NADW weakened. The absence of any significant NADW signal at the water depth of Site 984 during the climatic optimum contrasts sharply with subsequent interglacial peaks (MIS 5e and the Holocene). Despite the perturbed intermediate depth circulation, oceanic heat transport northeastward was not interrupted and may have contributed to the relatively mild interglacial conditions of MIS 9e.

  13. Foraminifera eco-biostratigraphy of the southern Evoikos outer shelf, central Aegean Sea, during MIS 5 to present

    NASA Astrophysics Data System (ADS)

    Drinia, Hara; Antonarakou, Assimina; Tsourou, Theodora; Kontakiotis, George; Psychogiou, Maria; Anastasakis, George

    2016-09-01

    The South Evoikos Basin is a marginal basin in the Aegean Sea which receives little terrigenous supply and its sedimentation is dominated by hemipelagic processes. Late Quaternary benthic and planktonic foraminifera from core PAG-155 are investigated in order to understand their response to the glacial-interglacial cycles in this region. The quantitative analysis of planktonic foraminifera, coupled with accelerator mass spectrometry (14C-AMS) radiocarbon date measurements, provide an integrated chrono-stratigraphic time framework over the last 90 ka (time interval between late Marine Isotopic Stages 5 and 1; MIS5-MIS1). The temporary appearance and disappearance as well as several abundance peaks in the quantitative distribution of selected climate-sensitive planktonic species allowed the identification of several eco-bioevents, useful to accurately mark the boundaries of the eco-biozones widely recognized in the Mediterranean records and used for large-scale correlations. The established bio-ecozonation scheme allows a detailed palaecological reconstruction for the late Pleistocene archive in the central Aegean, and furthermore provides a notable contribution for palaeoclimatic studies, facilitating intercorrelations between various oceanographic basins. The quantitative analyses of benthic foraminifera identify four distinct assemblages, namely Biofacies: Elphidium spp., Haynesina spp. Biofacies, characterized by neritic species, dominated during the transition from MIS 5 to MIS 4; Cassidulina laevigata/carinata Biofacies dominated till 42 ka (transgressive trend from MIS 4 to MIS 3); Bulimina gibba Biofacies dominated from 42 ka to 9.5 ka (extensive regression MIS 3,2 through lowstand and early transgression; beginning of MIS 1); Bulimina marginata, Uvigerina spp. Biofacies dominated from 9.5 ka to the present (late transgression through early highstand; MIS 1)., This study showed that the South Evoikos Basin which is characterized by its critical depths and

  14. Determination of the radiation-induced charge centroid in a MIS dielectric

    NASA Astrophysics Data System (ADS)

    Akulov, A. Ph.; Aphanasjev, V. V.; Gurtov, V. A.

    1992-09-01

    One of the modifications of the method of defining the charge quantity and the centroid in MIS structures based on field measurements of both of the insulator thresholds is described. Gate joining of two MIS structures after the charge has been taken away led to the formation of a structure similar to an SIS structure where the radiation-induced charge (RIC) was being investigated by means of C- V characteristics. Results of MNOS structures with nitride-oxide and oxide-nitride sublayer irradiation are reported. This sublayer was being created by Si nitriding or by nitriding of its thin dioxide layers accordingly. In the first case in the investigated field range (± 1.6 mV cm -1) the RIC centroid is localized at a distance not more than 0.15 of the insulator thickness of the substrate. In the case of an oxide-nitride sublayer (structures close to MNOS structures) negative charge was found on the external threshold and positive charge on the internal threshold. Calculation results of the centroid quantity are discussed in this case.

  15. ASYMPTOTICS FOR CHANGE-POINT MODELS UNDER VARYING DEGREES OF MIS-SPECIFICATION

    PubMed Central

    SONG, RUI; BANERJEE, MOULINATH; KOSOROK, MICHAEL R.

    2015-01-01

    Change-point models are widely used by statisticians to model drastic changes in the pattern of observed data. Least squares/maximum likelihood based estimation of change-points leads to curious asymptotic phenomena. When the change–point model is correctly specified, such estimates generally converge at a fast rate (n) and are asymptotically described by minimizers of a jump process. Under complete mis-specification by a smooth curve, i.e. when a change–point model is fitted to data described by a smooth curve, the rate of convergence slows down to n1/3 and the limit distribution changes to that of the minimizer of a continuous Gaussian process. In this paper we provide a bridge between these two extreme scenarios by studying the limit behavior of change–point estimates under varying degrees of model mis-specification by smooth curves, which can be viewed as local alternatives. We find that the limiting regime depends on how quickly the alternatives approach a change–point model. We unravel a family of ‘intermediate’ limits that can transition, at least qualitatively, to the limits in the two extreme scenarios. The theoretical results are illustrated via a set of carefully designed simulations. We also demonstrate how inference for the change-point parameter can be performed in absence of knowledge of the underlying scenario by resorting to subsampling techniques that involve estimation of the convergence rate. PMID:26681814

  16. Eolianite and coquinite as evidence of MIS 6 and 5, NW Black Sea coast, Turkey

    NASA Astrophysics Data System (ADS)

    Erginal, Ahmet Evren; Kıyak, Nafiye Güneç; Selim, Hamit Haluk; Bozcu, Mustafa; Öztürk, Muhammed Zeynel; Ekinci, Yunus Levent; Demirci, Alper; Elmas, Elmas Kırcı; Öztürk, Tuğba; Çakır, Çağlar; Karabıyıkoğlu, Mustafa

    2017-04-01

    This paper discusses the implications of a lowstand carbonate eolianite and overlying transgressive sequence of coquinite at Şile on the Turkish Black Sea coast based on composition, depositional characteristics and optical age estimations. The cross-bedded eolianite is a mixed ooid quartz grainstone in composition, yielding a depositional age matching MIS 6. It formed at the backshore of the paleobeach with the supply of sediment the from the beach face and offering insights into the drift of mixed shallow marine carbonates and siliciclastics together with radial ooids by onshore winds from a subaerially exposed high- to low-energy ooid shoals and oolitic sand complexes which developed parallel to the shoreline on the shallow shelf margin. During this lowstand, a low-relief dune retaining a record of opposing paleowind directions than that of prevalent northeasterly winds of today appears to have been lithified to form dune rock (aeolinite) under drier conditions compared to the present. Coinciding with MIS 5e, shallow marine coquina beds resting unconformably on the eolianite indicate the occurrence of the Mediterranean transgression during the last interglacial, as confirmed by benthic foraminifera within the high-salinity tolerant coquina shells.

  17. Control of haptic master - slave robot system for minimally invasive surgery (MIS)

    NASA Astrophysics Data System (ADS)

    Oh, J. S.; Shin, W. K.; Uhm, C. H.; Lee, S. R.; Han, Y. M.; Choi, S. B.

    2013-02-01

    In this work, 4 degrees-of-freedom (DOF) haptic master featuring electrorheological (ER) fluid is proposed and integrated with a slave. Using an ER fluid, the haptic master is devised which can generate a repulsive force/torque with the 4-DOF motion and provide stimulus information to operator. For realization of master-slave MIS system, an encoder is installed with the ER haptic master to establish the MIS master system. The motion command of the haptic master is realized by slave surgery robot. In order to follow the motion of the haptic master, the mechanism of slave surgery robot is devised. Accordingly, the haptic master-slave system is established by incorporating the slave robot with the haptic master device in which the repulsive force/torque and desired position are transferred to each other. In order to obtain the desired torque trajectories, a sliding mode controller (SMC) is designed and implemented. It has been demonstrated that the desired effective torque tracking control performance is well achieved using the proposed master-slave system.

  18. Sea-level highstands during the Last interglacial (MIS 5e) in Mallorca

    NASA Astrophysics Data System (ADS)

    Lorscheid, T.; Stocchi, P.; Rovere, A.; Gómez-Pujol, L.; Mann, T.; Fornos, J. J.

    2015-12-01

    Last Intergalcial in the island of Mallorca (NW Mediterranean) have been the subject of research since the early 60's (Butzer & Cuerda 1960). Despite both the location and stratigraphy of MIS 5e outcrops in the island are well known, the elevation of relative sea level (RSL) markers around the island has never been measured with high-accuracy topographic techniques (e.g. DGPS) and the interpretation of the paleo RSL has never been carried out using standardized definition of the indicative meaning of each RSL marker. In this study we present the results of two field trips aimed at measuring last interglacial deposits in Mallorca with high-accuracy GPS and at establishing, surveying modern shorelines as analogs, indicative ranges and reference water level values for RSL markers across the island. Using an earth-ice coupled GIA-model we performed several model-runs for investigating isostatic adjustment since MIS 5e in the island. These results are compared with the elevation of our deposits in the field and discussed in terms of tectonics and eustasy.

  19. Tumor-Specific Chromosome Mis-Segregation Controls Cancer Plasticity by Maintaining Tumor Heterogeneity

    PubMed Central

    Hu, Yuanjie; Ru, Ning; Xiao, Huasheng; Chaturbedi, Abhishek; Hoa, Neil T.; Tian, Xiao-Jun; Zhang, Hang; Ke, Chao; Yan, Fengrong; Nelson, Jodi; Li, Zhenzhi; Gramer, Robert; Yu, Liping; Siegel, Eric; Zhang, Xiaona; Jia, Zhenyu; Jadus, Martin R.; Limoli, Charles L.; Linskey, Mark E.; Xing, Jianhua; Zhou, Yi-Hong

    2013-01-01

    Aneuploidy with chromosome instability is a cancer hallmark. We studied chromosome 7 (Chr7) copy number variation (CNV) in gliomas and in primary cultures derived from them. We found tumor heterogeneity with cells having Chr7-CNV commonly occurs in gliomas, with a higher percentage of cells in high-grade gliomas carrying more than 2 copies of Chr7, as compared to low-grade gliomas. Interestingly, all Chr7-aneuploid cell types in the parental culture of established glioma cell lines reappeared in single-cell-derived subcultures. We then characterized the biology of three syngeneic glioma cultures dominated by different Chr7-aneuploid cell types. We found phenotypic divergence for cells following Chr7 mis-segregation, which benefited overall tumor growth in vitro and in vivo. Mathematical modeling suggested the involvement of chromosome instability and interactions among cell subpopulations in restoring the optimal equilibrium of tumor cell types. Both our experimental data and mathematical modeling demonstrated that the complexity of tumor heterogeneity could be enhanced by the existence of chromosomes with structural abnormality, in addition to their mis-segregations. Overall, our findings show, for the first time, the involvement of chromosome instability in maintaining tumor heterogeneity, which underlies the enhanced growth, persistence and treatment resistance of cancers. PMID:24282558

  20. Planning an MIS (manufacturing information system) for a job shop environment. [Manufacturing Information System

    SciTech Connect

    Cover, L.E.

    1987-01-01

    Several years ago the decision was made to computerize the information needed for management of the Mechanical and Electronics Support Division of Los Alamos National Laboratory and to centralize the resulting manufacturing information system (MIS) in one computer located at the main facility. The effort was contracted out to a software development company in July of 1981. After over five years, and in spite of tremendous investments of time and money in the existing system, the decision was made to phase out the existing system, start over, and try again to develop an information system that would meet the needs of the division. In January 1987, a study was initiated to formulate a long-range plan, which would effectively guide and direct MEC Division's information system development. Recent significant additions to the organization, changes in management staffing, and concerns for the adequacy and appropriateness of the hardware and software of the division's current MIS, led to the decision to perform the study. The study consisted of identifying the current and long-term information needs, consistent with the division's mission and goals, and recommending a plan to effectively implement information systems to fulfill these needs. Business Systems Planning (BSP), a methodology developed by IBM, was used in the study. 2 refs., 3 figs.

  1. Effect of interface traps parameters on admittance characteristics of the MIS (metal-insulator-semiconductor) tunnel structures

    NASA Astrophysics Data System (ADS)

    Jasiński, Jakub; Mazurak, Andrzej; Majkusiak, Bogdan

    2016-12-01

    Interface traps density (Nit) and gate insulator thickness (tox) impact on MIS tunnel structure electrical characteristics is discussed in respect to bias voltage range corresponding to inversion in the semiconductor substrate region. Effect of Nit and tox on equilibrium and non-equilibrium operation regime of the device is presented. Different models of the small-signal response of interface traps are proposed and discussed in respect to several phenomena related to the traps charging and discharging processes. Presented analysis was performed for the MIS structures with the gate dielectric made of silicon dioxide (SiO2) and hafnium oxide (HfOx). The obtained results proved that the surface density of interface traps (Nit) and the insulator thickness (tox) have correlated impact on the transition between equilibrium and non-equilibrium operation of the MIS tunnel structures.

  2. Contrasted ocean conditions in the northwest North Atlantic during marine isotope stages (MIS) 11, 5e and 1

    NASA Astrophysics Data System (ADS)

    de Vernal, Anne; Fréchette, Bianca; Hillaire-Marcel, Claude

    2014-05-01

    Cores raised during the IODP Expedition 303 in the north Atlantic were analysed to document paleoceanographical conditions during recent interglacials (cf. Hillaire-Marcel et al., Marine Geol. 2011). Two key sites illustrate conditions in the inner vs outer Labrador Sea, respectively at the southwest Greenland margin (Eirik Ridge Site 1305; 57° N-48° W) and the southern Labrador rise (Orphan Knoll Site 1302/1303; 50° N-45° W). Special attention was paid to marine isotope stages (MIS) 11 (ca. 424-324 ka), 5e (ca. 128-117 ka) and the Holocene (last 11,000 years). The microfossil content of sediments (dinocyst notably) and the isotopic composition of foraminifers indicate significant differences in the conditions that prevailed during these 3 interglacial stages. Optimal conditions with regard to sea-surface temperatures (SSTs) prevailed during MIS 5e (anomalies of about + 5° C) at both sites. However, occurrence of ice rafted debris (IRD) and variations in salinity suggest meltwater discharge along the Greenland and Labrador margins during the last interglacial. On the contrary, during MIS 11, SSTs were similar to modern off Greenland or slightly lower at Orphan Knoll, but salinity was higher at both sites and IRD close to nil, whereas both sites are presently under iceberg routes. Stable oxygen isotope values in the mesopelagic Neogloboquadrina pachyderma left coiled (Npl), are generally not unlike values observed during MIS 9 or 7, i.e., slightly higher than those which characterized MIS 5e and the present interglacial, particularly in the outer Labrador Sea. This points to either a higher salinity and or a lower temperature in the subsurface water layer occupied by Npl. Low IRD, high salinity together with relatively high 18O values in foraminifers suggest limited influence of meltwater from ice cap and sea ice during MIS 11, especially the first part of the interglacial.

  3. ENSO variability during MIS 11 (424-374 ka) from Tridacna gigas at Huon Peninsula, Papua New Guinea

    NASA Astrophysics Data System (ADS)

    Ayling, Bridget F.; Chappell, John; Gagan, Michael K.; McCulloch, Malcolm T.

    2015-12-01

    Marine Isotope Stage 11 (MIS 11) from ∼424,000 to 374,000 yrs ago included one of the longest and warmest interglacials of the last 800,000 yrs, and is a potential analogue for the Holocene due to the similarity of Earth's orbital configuration at this time. The question of how the El Niño-Southern Oscillation (ENSO) responds to warmer background climates remains unanswered and is critical to understand how the ENSO system will evolve under the influence of anthropogenic warming. In this study, we present a 35 yr-long, high-resolution record of MIS 11 climate variability in the Western Pacific Warm Pool (WPWP) based on coupled measurements of skeletal Mg/Ca and δ18O in giant Tridacna gigas clams from Huon Peninsula, Papua New Guinea. The δ18O of modern T. gigas from Huon Peninsula faithfully records sea surface temperature, salinity/rainfall and regional ENSO variability. The geochemical integrity of the MIS 11 T. gigas for recording paleo-ENSO events was established through trace element screening, detailed petrography and SEM analysis. The fossil T. gigas δ18O record indicates that ENSO was operating during a 35-yr window in MIS 11, but with fewer events of shorter duration compared to those experienced during the last 100 yrs. The suppressed ENSO variability in the MIS 11 T. gigas record corresponds with a reduction in the amplitude of the average annual cycle in δ18O values. Distinctive changes in local insolation seasonality, and T. gigas δ18O, brought about by changes in Earth's orbit, provide an additional geochronological constraint on the timing of reef growth at Huon Peninsula to around 402 ka during the MIS 11.3 sub-stage (∼424-395 ka).

  4. Glacial induced closure of the Panamanian Gateway during Marine Isotope Stages (MIS) 95-100 (∼2.5 Ma)

    NASA Astrophysics Data System (ADS)

    Groeneveld, J.; Hathorne, E. C.; Steinke, S.; DeBey, H.; Mackensen, A.; Tiedemann, R.

    2014-10-01

    The final phase of the closure of the Panamanian Gateway and the intensification of Northern Hemisphere Glaciation (NHG) both occurred during the Late Pliocene. Glacial-interglacial (G-IG) variations in sea level might, therefore, have had a significant impact on the remaining connections between the East Pacific and the Caribbean. Here, we present combined foraminiferal Mg/Ca and δ18O measurements from Ocean Drilling Program (ODP) Site 1241 from the East Pacific and ODP Site 999 from the Caribbean. The studied time interval covers the first three major G-IG Marine Isotope Stages (MIS 95-100, ∼2.5 Ma) after the intensification of NHG. Analyses were performed on the planktonic foraminifera Neogloboquadrina dutertrei and Globigerinoides sacculifer, representing water mass properties in the thermocline and the mixed-layer, respectively. Changes in sea water temperature, relative salinity, and water column stratification strongly suggest that the Panamanian Gateway temporarily closed during glacial MIS 98 and 100, as a result of changes in ice volume equivalent to a drop in sea level of 60-90 m. Reconstructed sea surface temperatures (SST) from G. sacculifer show a glacial decrease of 2.5 °C at Site 1241, but increases of up to 3 °C at Site 999 during glacial MIS 98 and 100 suggesting that the Panamanian Gateway closed during these glacial periods. The Mg/Ca-temperatures of N. dutertrei remain relatively stable in the East Pacific, but do show a 3 °C warming in the Caribbean at the onset of these glacial periods suggesting that the closing of the gateway also changed the water column stratification. We infer that the glacial closure of the gateway allowed the Western Atlantic Warm Pool to extend into the southern Caribbean, increasing SST (G. sacculifer) and deepening the thermocline (N. dutertrei). Additionally, ice volume appears to have become large enough during MIS 100 to survive the relatively short lasting interglacial MIS 99 so that the gateway remained

  5. Late Quaternary MIS 6-8 shoreline features of pluvial Owens Lake, Owens Valley, eastern California

    USGS Publications Warehouse

    Jayko, A.S.; Bacon, S.N.

    2008-01-01

    The chronologic history of pluvial Owens Lake along the eastern Sierra Nevada in Owens Valley, California, has previously been reported for the interval of time from ca. 25 calibrated ka to the present. However, the age, distribution, and paleoclimatic context of higher-elevation shoreline features have not been formally documented. We describe the location and characteristics of wave-formed erosional and depositional features, as well as fluvial strath terraces that grade into an older shoreline of pluvial Owens Lake. These pluvial-lacustrine features are described between the Olancha area to the south and Poverty Hills area to the north, and they appear to be vertically deformed -20 ?? 4 m across the active oblique-dextral Owens Valley fault zone. They occur at elevations from 1176 to 1182 m along the lower flanks of the Inyo Mountains and Coso Range east of the fault zone to as high as -1204 m west of the fault zone. This relict shoreline, referred to as the 1180 m shoreline, lies -20-40 m higher than the previously documented Last Glacial Maximum shoreline at -1160 m, which occupied the valley during marine isotope stage 2 (MIS 2). Crosscutting relations of wave-formed platforms, notches, and sandy beach deposits, as well as strath terraces on lava flows of the Big Pine volcanic field, bracket the age of the 1180 m shoreline to the time interval between ca. 340 ?? 60 ka and ca. 130 ?? 50 ka. This interval includes marine oxygen isotope stages 8-6 (MIS 8-6), corresponding to 260-240 ka and 185-130 ka, respectively. An additional age estimate for this shoreline is provided by a cosmogenic 36Cl model age of ca. 160 ?? 32 ka on reefal tufa at ???1170 m elevation from the southeastern margin of the valley. This 36Cl model age corroborates the constraining ages based on dated lava flows and refines the lake age to the MIS 6 interval. Documentation of this larger pluvial Owens Lake offers insight to the hydrologic balance along the east side of the southern Sierra

  6. Soft-tissue motion tracking and structure estimation for robotic assisted MIS procedures.

    PubMed

    Stoyanov, Danail; Mylonas, George P; Deligianni, Fani; Darzi, Ara; Yang, Guang Zhong

    2005-01-01

    In robotically assisted laparoscopic surgery, soft-tissue motion tracking and structure recovery are important for intraoperative surgical guidance, motion compensation and delivering active constraints. In this paper, we present a novel method for feature based motion tracking of deformable soft-tissue surfaces in totally endoscopic coronary artery bypass graft (TECAB) surgery. We combine two feature detectors to recover distinct regions on the epicardial surface for which the sparse 3D surface geometry may be computed using a pre-calibrated stereo laparoscope. The movement of the 3D points is then tracked in the stereo images with stereo-temporal constrains by using an iterative registration algorithm. The practical value of the technique is demonstrated on both a deformable phantom model with tomographically derived surface geometry and in vivo robotic assisted minimally invasive surgery (MIS) image sequences.

  7. New Spectral Method for Halo Particle Definition in Intense Mis-matched Beams

    SciTech Connect

    Dorf, Mikhail A.; Davidson, Ronald C.; Startsev, Edward A.

    2011-04-27

    An advanced spectral analysis of a mis-matched charged particle beam propagating through a periodic focusing transport lattice is utilized in particle-in-cell (PIC) simulations. It is found that the betatron frequency distribution function of a mismatched space-charge-dominated beam has a bump-on-tail structure attributed to the beam halo particles. Based on this observation, a new spectral method for halo particle definition is proposed that provides the opportunity to carry out a quantitative analysis of halo particle production by a beam mismatch. In addition, it is shown that the spectral analysis of the mismatch relaxation process provides important insights into the emittance growth attributed to the halo formation and the core relaxation processes. Finally, the spectral method is applied to the problem of space-charge transport limits.

  8. The effect of Be and Cr electrode deposition rate on the performance of MIS solar cells

    NASA Astrophysics Data System (ADS)

    Moharram, A. H.; Panayotatos, P.; Yeh, J. L.; Lalevic, B.

    1985-07-01

    An experimental study has been performed on MIS solar cells with Be, Cr and layered Cr-Be electrodes on single crystal Si, Wacker and Monsanto poly-Si substrates. Electrical characterization in the dark and under illumination was correlated to X-ray and Auger spectroscopy results. It was found that the electrode deposition rate directly affects the oxygen content of the electrodes for all metal-substrate configurations. This oxygen is believed to originate from the deposition ambient as well as from the SiO2 layer. In the case of cells with Cr and layered Cr-Be electrodes oxygen acts to reduce the electrode work function (thus increasing the open-circuit voltage) in direct proportion to the relative content of oxygen to chromium.

  9. Studies on evaporated cesium incorporation in MIS inversion layer solar cells

    NASA Astrophysics Data System (ADS)

    Guo, L.; Hezel, R.

    1994-09-01

    For MIS inversion layer solar cells with plasma silicon nitride both as antireflection coating and charged dielectric, cesium was incorporated into the nitride film by thermal evaporation. Compared to the presently used technique of dipping the silicon wafer into an alcoholic solution of CsCl, cesium evaporation yields higher fixed interface charge densities resulting in a lower inversion layer sheet resistance. As a very important result, even for intense and very energetic u.v. light ( λ ⩽ 180 nm) not present in the solar spectrum, no negative effect on the cell properties could be observed. This makes it possible to fully utilize the high response of the inversion layer solar cell in the ultraviolet range.

  10. Parameters influencing the performance and stability of CdSe MIS solar cells

    SciTech Connect

    Rickus, E.

    1982-09-01

    CdSe MIS solar cells with ZnSe as ''I-layer'' are very insensitive to oxidative ambients and to humidity even in the unsealed state. They show lower sensitivity to ''I-film'' thickness-variations than native-oxide devices. The use of wide-bandgap semiconductor as ''I-film'' opens new ways to influence the energetic position of the potential barrier caused by the ''I-layer''. Expecially doping of the ZnSe-film results in a distinct enhancement of the fill factor. AM 1-efficiencies of 6.6 percent on 1 cm/sup 2/ active area have been achieved with relatively low effort. Further optimizations will enhance the efficiency of this simple, economic solar cell.

  11. Admittance Investigation of MIS Structures with HgTe-Based Single Quantum Wells.

    PubMed

    Izhnin, Ihor I; Nesmelov, Sergey N; Dzyadukh, Stanislav M; Voitsekhovskii, Alexander V; Gorn, Dmitry I; Dvoretsky, Sergey A; Mikhailov, Nikolaj N

    2016-12-01

    This work presents results of the investigation of admittance of metal-insulator-semiconductor structure based on Hg1 - x Cd x Te grown by molecular beam epitaxy. The structure contains a single quantum well Hg0.35Cd0.65Te/HgTe/Hg0.35Cd0.65Te with thickness of 5.6 nm in the sub-surface layer of the semiconductor. Both the conductance-voltage and capacitance-voltage characteristics show strong oscillations when the metal-insulator-semiconductor (MIS) structure with a single quantum well based on HgTe is biased into the strong inversion mode. Also, oscillations on the voltage dependencies of differential resistance of the space charge region were observed. These oscillations were related to the recharging of quantum levels in HgTe.

  12. High capacitance density MIS capacitor using Si nanowires by MACE and ALD alumina dielectric

    NASA Astrophysics Data System (ADS)

    Leontis, I.; Botzakaki, M. A.; Georga, S. N.; G. Nassiopoulou, A.

    2016-06-01

    High capacitance density three-dimensional (3D) metal-insulator-semiconductor (MIS) capacitors using Si nanowires (SiNWs) by metal-assisted chemical etching and atomic-layer-deposited alumina dielectric film were fabricated and electrically characterized. A chemical treatment was used to remove structural defects from the nanowire surface, in order to reduce the density of interface traps at the Al2O3/SiNW interface. SiNWs with two different lengths, namely, 1.3 μm and 2.4 μm, were studied. A four-fold capacitance density increase compared to a planar reference capacitor was achieved with the 1.3 μm SiNWs. In the case of the 2.4 μm SiNWs this increase was ×7, reaching a value of 4.1 μF/cm2. Capacitance-voltage (C-V) measurements revealed that, following a two-cycle chemical treatment, frequency dispersion at accumulation regime and flat-band voltage shift disappeared in the case of the 1.3 μm SiNWs, which is indicative of effective removal of structural defects at the SiNW surface. In the case of the 2.4 μm SiNWs, frequency dispersion at accumulation persisted even after the two-step chemical treatment. This is attributed to a porous Si layer at the SiNW tops, which is not effectively removed by the chemical treatment. The electrical losses of MIS capacitors in both cases of SiNW lengths were studied and will be discussed.

  13. High-elevation paleoenvironmental change during MIS 6-4 in the central Rockies of Colorado as determined from pollen analysis

    NASA Astrophysics Data System (ADS)

    Anderson, R. Scott; Jiménez-Moreno, Gonzalo; Ager, Thomas; Porinchu, David F.

    2014-11-01

    Paleoecological studies from Rocky Mountain (USA) high elevations encompassing the previous interglacial (MIS 5e) are rare. The ~ 10-m composite profile from the Ziegler Reservoir fossil site (2705 m asl) of central Colorado allows us to determine paleoenvironments from Marine Oxygen Isotope Stages (MIS) 6- 4 using pollen zones that are approximately equivalent to marine oxygen isotope stages. During Pollen Zone (PZ) 6 time, pollen assemblages dominated by Artemisia (sagebrush) suggest that alpine tundra or steppe occurred nearby. The transition to PZ 5e was characterized by a rapid increase in tree pollen, initially Picea (spruce) and Pinus (pine) but also Quercus (oak) and Pseudotsuga menziesii (Douglas-fir). Non-arboreal pollen (NAP) types increased during PZ 5d, while Abies (fir) and Juniperus (juniper) increased during PZ 5c. Pollen evidence suggests that temperatures during PZ 5b were as cold as during PZ 6, with the site again surrounded by alpine tundra. Picea dominated during PZ 5a before the onset of cooler conditions during PZ 4. The MIS 6-MIS 5e transition here was similar to the MIS 2-MIS 1 transition at other Rocky Mountain sites. However, the Ziegler Reservoir pollen record contains evidence suggesting unexpected climatic trends at this site, including a warmer-than-expected MIS 5d and cooler-than-expected MIS 5b.

  14. The monsoon imprint during the `atypical' MIS 13 as seen through north and equatorial Indian Ocean records

    NASA Astrophysics Data System (ADS)

    Caley, Thibaut; Malaizé, Bruno; Bassinot, Franck; Clemens, Steven C.; Caillon, Nicolas; Linda, Rossignol; Charlier, Karine; Rebaubier, Helene

    2011-09-01

    Previous studies have suggested that Marine Isotope Stage (MIS) 13, recognized as atypical in many paleoclimate records, is marked by the development of anomalously strong summer monsoons in the northern tropical areas. To test this hypothesis, we performed a multi-proxy study on three marine records from the tropical Indian Ocean in order to reconstruct and analyse changes in the summer Indian monsoon winds and precipitations during MIS 13. Our data confirm the existence of a low-salinity event during MIS 13 in the equatorial Indian Ocean but we argue that this event should not be considered as "atypical". Taking only into account a smaller precession does not make it possible to explain such precipitation episode. However, when considering also the larger obliquity in a more complete orbitally driven monsoon "model," one can successfully explain this event. In addition, our data suggest that intense summer monsoon winds, although not atypical in strength, prevailed during MIS 13 in the western Arabian Sea. These strong monsoon winds, transporting important moisture, together with the effect of insolation and Eurasian ice sheet, are likely one of the factors responsible for the intense monsoon precipitation signal recorded in China loess, as suggested by model simulations.

  15. WindSat Soil Moisture and Vegetation Validation and Performance Prediction for the NPOESS Microwave Imager/Sounder (MIS)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The National Polar-orbiting Operational Environmental Satellite System’s (NPOESS) Microwave Imager/Sounder (MIS) instrument is in development, with soil moisture sensing depth as one of the two Key Performance Parameters (KPPs). The other one is ocean surface wind speed precision. Based on the curre...

  16. Enhancing Student Learning across Disciplines: A Case Example Using a Systems Analysis and Design Course for MIS and ACS Majors

    ERIC Educational Resources Information Center

    Surendran, Ken; Ehie, Ike C.; Somarajan, Chellappan

    2005-01-01

    This paper illustrates an approach used to enhance student learning outcomes in a combined cross-listed Systems Analysis and Design (SA&D) course and examines benefits perceived by students through analysis of assessment and students feedback. The SA&D course is a required course in both the Management Information Systems (MIS) major and the…

  17. The Use of Management Information Systems (MIS) in Decision Making in the South-West Nigerian Universities

    ERIC Educational Resources Information Center

    Ajayi, I. A.; Omirin, Fadekemi F.

    2007-01-01

    This study investigated the use of Management Information Systems (MIS) in decision-making on long-term planning, short-term planning and budgeting in the South-West Nigerian Universities. The study used the descriptive research design of the survey type. Data were collected from a sample of 600 subjects consisting of 400 academic staff holding…

  18. New chronology for Pleistocene shoreline deposits on the central US Atlantic Coast: implication for relative sea level during MIS 5 and 7

    NASA Astrophysics Data System (ADS)

    Shen, Z.; Wright, E. E.; Mauz, B.

    2015-12-01

    Emerged shoreline deposits are the most important records for studying relative sea level (RSL) of previous interglacial and understanding glacial/hydro isostasy. The Lower Atlantic Coastal Plain in the U.S. is characterized by coast-parallel barrier beaches and back-barrier deposits formed during maximum Pleistocene marine transgressions. Thus, they offer an opportunity to investigate RSL changes of multiple Pleistocene interglacials. However, the chronology of these deposits has been controversial due to the lack of reliable numerical ages, especially in South Carolina. Here we present stratigraphy and OSL dating results for both the late Pleistocene barrier and the back-barrier deposits between Georgetown and Myrtle Beach, South Carolina and discuss their sea-level implications. The barrier ridge near Georgetown is covered by about 1 m aeolian deposits dated to ~20 ka. The aeolian deposits overlie humic sand and laminated beach sand that is dated to ~80 ka, corresponding to Marine Isotope Stage (MIS) 5a. Stratigraphy of back-barrier deposits exposed along the Intracoastal Waterway near Myrtle Beach reveals a unit of back-barrier deposits separated from underlying shallow marine deposits by a paleosol. The back-barrier deposits are dated to MIS 5a while the lower shallow marine deposits yielded OSL ages corresponding to MIS 7 (~200 ka). The beach sand near Georgetown and the back-barrier deposits near Myrtle Beach together suggest that MIS 5a RSL was up to about 5 m above present sea level while the shallow marine deposits near Myrtle Beach indicate a MIS 7 RSL at or above present sea level along the northeastern South Carolina coast. The MIS 5a and MIS 7 RSL are in agreement with previous studies along other U.S. Atlantic coast. However, the missing of MIS 5e deposits between MIS 5a and MIS 7 deposits at the exposure near Myrtle Beach needs be confirmed with additional work.

  19. Marine Isotope Stages (MIS) 96-101: Glacial induced closure of the Panamanian Gateway

    NASA Astrophysics Data System (ADS)

    Groeneveld, Jeroen; Debey, Henry; Hathorne, Ed C.; Steinke, Stephan

    2010-05-01

    We present combined Mg/Ca and δ18O measurements from ODP Site 1241 from the east Pacific and ODP Site 999 from the Caribbean. The studied time interval covers the first major glacial-interglacial cycles (MIS96-101) after intensification of Northern Hemisphere Glaciation. Analyses were performed on the planktic foraminifers Neogloboquadrina dutertrei and Globigerinoides sacculifer, representing water mass properties in the thermocline and the mixed layer respectively. Data resolution is aimed to be able to resolve millennial scale variations to constrain the changes in water mass conditions during MIS96-101. Aim of the study is to test the theory that the Panamanian Gateway temporarily closed during glacial MIS 96, 98, and 100 due to a drop in sea level of 50-80 m. This was first suggested in Groeneveld et al., (in prep.) and might have provided the necessary conditions to allow the Great American Biotic Interchange, the large scale migration of mammals from South to North America and vice versa. As this exchange would have required more arid conditions in Central America to allow the fauna, which was mainly adapted to a savannah-like environment, to cross, a glacial period would have provided the right conditions. Reconstruction of sea water temperatures can indicate if and when the gateway closed. With an open Panamanian Gateway relatively cold water flowed from the Pacific into the Caribbean. With the onset of glacial conditions sea surface temperatures (SST) expectedly would show a decrease in the east Pacific (Site 1241). But, SSTs in the Caribbean (Site 999) are expected to rise as no longer relatively cold Pacific water is entering the Caribbean, but rather the warmer waters from the Western Atlantic Warm Pool advanced from the north to the core location. Indeed, reconstructed SSTs from G. sacculifer show a decrease of 2.5° C at Site 1241 and an increase of 3° C at Site 999 suggesting that the Panamanian Gateway truly was closed during the glacial stage

  20. Rayleigh waves ellipticity and mode mis-identificationin multi-channel analysis of surface waves

    NASA Astrophysics Data System (ADS)

    Boaga, J.; Cassiani, G.; Strobbia, C. L.; Vignoli, G.

    2012-12-01

    The Surface Wave Method is a popular tool for geotechnical characterization since it supplies a cost effective testing procedure capable of retrieving the shear wave velocity structure of the near surface. Several acquisition and processing approaches have been developed to infer the Rayleigh wave dispersion curve which is then inverted. Typically, single component vertical and multi channel receivers are used. In most cases the inversion of the dispersion properties is carried out assuming that the experimental dispersion curve corresponds to a single mode, mostly the fundamental Rayleigh mode, unless clear evidence dictates the existence of a more complex response, e,g. in presence of low velocity layers and inversely dispersive sites. A correct identification of the modes is essential to avoid serious misinterpretation of the subsoil model. Here we consider the typical case of higher mode mis-identification known as 'osculation' ('kissing'). In general it is called 'osculation point' the point where the energy peak shifts at low frequencies from the fundamental to the first higher mode. This jump occurs, with a continuous smooth transition, around a well-define frequency where the two modes get very close to each other reaching similar Rayleigh velocity. It is known 'osculation' happens generally in presence of strong velocity contrasts, typically with a fast bedrock underlying loose sediments. The practical limitations of the acquired data affect the spectral and modal resolution, making it often impossible to identify the presence of more than one mode. In some cases, modes have a common root and cannot be separated at the osculation point. In such cases, mode misidentification can create a large overestimation of the bedrock velocity and a large error on its depth. In this work we examine the subsoil conditions that can generate this unwanted condition, and the common field acquisition procedures that can contribute to producing data having such deceptive

  1. Role of the tropical Pacific Ocean in strengthening the East Asian Monsoon: Climate model study of MIS-13

    NASA Astrophysics Data System (ADS)

    Karami, M.; Herold, N.; Yin, Q.; Berger, A.

    2012-12-01

    Studying past climates is a valuable approach to improve our understanding of the present and future climate systems. Among the significant events in the history of climate, the interglacial periods are good candidates for representation of the future climate because of their astronomical characteristics and their similarity to predicted anthropogenic warming. Moreover, some interglacials exhibited significant changes in atmospheric and oceanic properties due to only small changes in their climatic forcing (greenhouse gases and solar insolation) which also make them a good case for investigating past climates. For instance, the interglacial stage of around 0.5 Ma identified as Marine Isotopic stage 13 (MIS-13), the focus of this study, was characterized by extremely strong East Asian and Indian summer monsoons while the CO2 and CH4 levels were lower and seasonal radiation energy could reach up to 50 Wm-2 higher than today. The extreme monsoon precipitation is quite unexpected for a climate with such forcing. To understand the physics-based mechanism that enhances the East Asian Summer Monsoon (EASM) during MIS-13, we used two fully coupled general circulation models, the HadCM3 and CCSM3. In MIS-13 experiments, concentrations of greenhouse gases were prescribed lower than in pre-industrial and seasonal insolation characterised by Northern-Hemisphere (NH) summer occurring at perihelion instead of aphelion as it does today. Results of both models confirm increased summer precipitation in the monsoon regions. We find that the tropical Pacific Ocean plays a major role in strengthening the EASM in MIS-13. Simulations of MIS-13 show stronger easterly surface winds along the equatorial Pacific and a subsequent increase in the mean thermocline tilt, in addition to a westward shift of the cold tongue. These changes alter the background climatic state of the equatorial Pacific towards a La Niña-type state. The interannual variability around the La Niña-like background

  2. Unexpected weak seasonal climate in the western Mediterranean region during MIS 31, a high-insolation forced interglacial

    NASA Astrophysics Data System (ADS)

    Oliveira, Dulce; Sánchez Goñi, Maria Fernanda; Naughton, Filipa; Polanco-Martínez, J. M.; Jimenez-Espejo, Francisco J.; Grimalt, Joan O.; Martrat, Belen; Voelker, Antje H. L.; Trigo, Ricardo; Hodell, David; Abrantes, Fátima; Desprat, Stéphanie

    2017-04-01

    Marine Isotope Stage 31 (MIS 31) is an important analogue for ongoing and projected global warming, yet key questions remain about the regional signature of its extreme orbital forcing and intra-interglacial variability. Based on a new direct land-sea comparison in SW Iberian margin IODP Site U1385 we examine the climatic variability between 1100 and 1050 ka including the ;super interglacial; MIS 31, a period dominated by the 41-ky obliquity periodicity. Pollen and biomarker analyses at centennial-scale-resolution provide new insights into the regional vegetation, precipitation regime and atmospheric and oceanic temperature variability on orbital and suborbital timescales. Our study reveals that atmospheric and SST warmth during MIS 31 was not exceptional in this region highly sensitive to precession. Unexpectedly, this warm stage stands out as a prolonged interval of a temperate and humid climate regime with reduced seasonality, despite the high insolation (precession minima values) forcing. We find that the dominant forcing on the long-term temperate forest development was obliquity, which may have induced a decrease in summer dryness and associated reduction in seasonal precipitation contrast. Moreover, this study provides the first evidence for persistent atmospheric millennial-scale variability during this interval with multiple forest decline events reflecting repeated cooling and drying episodes in SW Iberia. Our direct land-sea comparison shows that the expression of the suborbital cooling events on SW Iberian ecosystems is modulated by the predominance of high or low-latitude forcing depending on the glacial/interglacial baseline climate states. Severe dryness and air-sea cooling is detected under the larger ice volume during glacial MIS 32 and MIS 30. The extreme episodes, which in their climatic imprint are similar to the Heinrich events, are likely related to northern latitude ice-sheet instability and a disruption of the Atlantic Meridional Overturning

  3. Climate and vegetation since the Last Interglacial (MIS 5e) in a putative glacial refugium, northern Idaho, USA

    NASA Astrophysics Data System (ADS)

    Herring, Erin M.; Gavin, Daniel G.

    2015-06-01

    There are very few terrestrial sediment records from North America that contain a nearly continuous sequence spanning from the Last Interglacial period to the present. We present stratigraphic records of pollen and several other proxies from a Carex-dominated wetland, Star Meadows, located 140 km south of the maximum extent of the Cordilleran Ice Sheet and near the current southern extent of interior mesic forests in northern Idaho. Many species in this region are disjunct by 160 km of arid steppe and dry forest from their more extensive distribution along the Pacific Northwest coast and may have survived in an interior refugium. The chronology for the upper 251 cm was determined by six radiocarbon dates and one tephra deposit, and the age of the remainder of the core (251-809 cm) was estimated by correlation with SPECMAP δ18O. Fluctuating water levels were inferred from alternating peat, biogenic silica, and aquatic pollen types. During MIS 5e the region was warmer and drier than today and was dominated by Pinus (likely Pinus contorta) mixed conifer forest surrounding a Carex meadow. A cool-moist climate (MIS 5b-5d) soon developed, and the site was inundated with deep water. Pollen indicated wetland vegetation (Betula glandulosa, Typhaceae, and Salix) developed around a lake with a Pseudotsuga/Larix and Picea forest on the surrounding slopes. During MIS 5a, a warmer climate supported a Pseudotsuga/Larix, Abies, and Picea forest on the surrounding hillsides and a Carex-dominated environment within a dry meadow. From MIS 4 to MIS 3, a cool and wet Pinus and Picea forest predominated. Water levels rose, enabling Nuphar to persist within a perennial lake while a sedge fen established along the lake margin. As climate transitioned into MIS 2, a cooler and drier climate supported a Pinus and Picea subalpine parkland, though water levels remained high enough to support Nuphar. During the Last Glacial Maximum the sediment was mainly silt and clay with high Artemisia and

  4. The MIS 5 palaeoenvironmental record in the SE Mediterranean coast of the Iberian Peninsula (Río Antas, Almería, Spain)

    NASA Astrophysics Data System (ADS)

    Torres, T.; Ortiz, J. E.; Blázquez, A. M.; Ruiz Zapata, B.; Gil, M. J.; Martín, T.; Sánchez-Palencia, Y.

    2015-08-01

    Landwards of a MIS5 bar, a borehole core (SRA) was analyzed to establish the relationship between the lagoonal record and the raised beach deposits in the surroundings of the Antas river mouth and to reconstruct the Pleistocene palaeoenvironmental evolution of the southern Mediterranean coast of the Iberian Peninsula. 63 samples were recovered for amino acid racemization dating, 86 samples for sedimentological and paleontological determination, 37 samples for pollen identification and 54 for biomarker analysis. AAR revealed that the borehole record contains MIS11, MIS6 and MIS5 deposits, the latter extensively represented. During the end of MIS6 and MIS5, a sand barrier developed and created a shallow lagoon with alternating terrestrial inputs this process being common in other Mediterranean realms. Litho- and biofacies allowed the identification of distinct paleoenvironments through time, with the presence of a lagoonal environment alternating with alluvial fan progradation. Biomarkers indicated constant input from terrestrial plants, together with variable development of aquatic macrophytes. The palynological content allowed the reconstruction of the paleoclimatological conditions during MIS6 and 5, with evidence of seven scenarios characterized by alternating arid and relatively humid conditions.

  5. Using bones to shape stones: MIS 9 bone retouchers at both edges of the Mediterranean Sea.

    PubMed

    Blasco, Ruth; Rosell, Jordi; Cuartero, Felipe; Fernández Peris, Josep; Gopher, Avi; Barkai, Ran

    2013-01-01

    A significant challenge in Prehistory is to understand the mechanisms involved in the behavioural evolution of human groups. The degree of technological and cultural development of prehistoric groups is assessed mainly through stone tools. However, other elements can provide valuable information as well. This paper presents two bone retouchers dated to the Middle Pleistocene MIS 9 used for the shaping of lithic artefacts. Originating from Bolomor Cave (Spain) and Qesem Cave (Israel), these two bone retouchers are among the earliest of the Old World. Although the emergence of such tools might be found in the latest phases of the Acheulean, their widespread use seems to coincide with independently emergent post-Acheulean cultural complexes at both ends of the Mediterranean Sea: the post-Acheulean/pre-Mousterian of Western Europe and the Acheulo Yabrudian Cultural Complex of the Levant. Both entities seem to reflect convergent processes that may be viewed in a wider cultural context as reflecting new technology-related behavioural patterns as well as new perceptions in stone tool manufacturing.

  6. MIS Requirements for Managing a Hospital under ‘Per Case’ Reimbursement

    PubMed Central

    Steinwachs, Donald M.; Fahey, Maureen; Horky, Ralph; Perkel, Sara; Tower, David

    1979-01-01

    Maryland is the first state to regulate reimbursement of some of its hospitals on the basis of admissions, instead of services, with adjustments for case mix. This form of reimbursement is intended to provide incentives for increasing efficiency and reducing service intensity (i.e., length of stay and use of ancillaries). Any savings achieved by hospitals may be retained, while losses must be absorbed. Existing management information systems (MIS) are not oriented toward producing data on admissions, with the exception of the Uniform Hospital Discharge Abstract Data Set (UHDADS). Using UHDADS, supplemented with detailed charge data, two issues are being addressed in the Department of Medicine, The Johns Hopkins Hospital: (1) can charges per admission be predicted from a minimal data set? (2) can diagnostic specific trends in utilization and charges be detected on a timely basis? Results of multivariate analysis have shown that significant variations in length of stay among diagnostic categories are frequently not associated with significant variations in charges. Through a detailed analysis of selected diagnostic groups, the need for a treatment pattern classification to compliment the diagnostic classification of admissions has been identified. A classification system based on level and type of treatment charges has been tested. Effectiveness is being measured by its capability to detect trends in charges, and to characterize resource use patterns for management reporting.

  7. Modelled interglacial carbon cycle dynamics during the Holocene, the Eemian and Marine Isotope Stage (MIS) 11

    NASA Astrophysics Data System (ADS)

    Kleinen, Thomas; Brovkin, Victor; Munhoven, Guy

    2016-11-01

    Trends in the atmospheric concentration of CO2 during three recent interglacials - the Holocene, the Eemian and Marine Isotope Stage (MIS) 11 - are investigated using an earth system model of intermediate complexity, which we extended with process-based modules to consider two slow carbon cycle processes - peat accumulation and shallow-water CaCO3 sedimentation (coral reef formation). For all three interglacials, model simulations considering peat accumulation and shallow-water CaCO3 sedimentation substantially improve the agreement between model results and ice core CO2 reconstructions in comparison to a carbon cycle set-up neglecting these processes. This enables us to model the trends in atmospheric CO2, with modelled trends similar to the ice core data, forcing the model only with orbital and sea level changes. During the Holocene, anthropogenic CO2 emissions are required to match the observed rise in atmospheric CO2 after 3 ka BP but are not relevant before this time. Our model experiments show a considerable improvement in the modelled CO2 trends by the inclusion of the slow carbon cycle processes, allowing us to explain the CO2 evolution during the Holocene and two recent interglacials consistently using an identical model set-up.

  8. Geochemical proxies and millennial-scale climate variability during MIS 3 at Lake Chalco, central Mexico

    NASA Astrophysics Data System (ADS)

    Torres, E.; Lozano, S.; Roy, P.; Ortega, B.; Caballero, M.

    2013-05-01

    The Basin of Mexico (20N, 99W; 2240 m.a.s.l.) is present at the northern limit of the American tropics and is surrounded by up to 5400 m high mountains. The Lake Chalco is situated at the southern part of the basin and spreads over 120 km2. The precipitation in the modern era is influenced by the seasonal displacement of the Intertropical Convergence Zone and the high-pressure belt located at about 35 N. Five cores were drilled (up to 122.5 m depth) in order to document climate variability in paleohydrological conditions during the late Quaternary. The age model includes several 14C dates and tephra layers present in the upper 25 m of the core. We documented millennial-scale events during MIS 3 based on geochemical data (total organic carbon (TOC), total inorganic carbon (TIC), C/N ratio) and abundance of charcoal particles. By temporal correlation with GISP2 core we founded that Greenland interstadials match with TOC percentages suggesting wet conditions while stadials match with high TIC percentages and high charcoal concentrations suggesting dry conditions. We compared our data with speleothem records (δ18O) from Fort Station Cave (New Mexico) and Terciopelo Cave (Costa Rica), our preliminary results indicate that Chalco record has a similar climatic signal as Terciopelo Cave, both presented wet interstadials and dry stadials which appear to have been regulated by the seasonal migration of the ITCZ.

  9. Northern Borneo stalagmite records reveal West Pacific hydroclimate across MIS 5 and 6

    NASA Astrophysics Data System (ADS)

    Carolin, Stacy A.; Cobb, Kim M.; Lynch-Stieglitz, Jean; Moerman, Jessica W.; Partin, Judson W.; Lejau, Syria; Malang, Jenny; Clark, Brian; Tuen, Andrew A.; Adkins, Jess F.

    2016-04-01

    Over the past decades, tropical stalagmite δ18O records have provided valuable insight on glacial and interglacial hydrological variability and its relationship to a variety of natural climate forcings. The transition out of the penultimate glaciation (MIS 6) represents an important target for tropical hydroclimate reconstructions, yet relatively few such reconstructions resolve this transition. Particularly, comparisons between Termination 1 and 2 provide critical insight on the extent and influence of proposed climate mechanisms determined from paleorecords and model experiments spanning the recent deglaciation. Here we present a new compilation of western tropical Pacific hydrology spanning 0-160 ky BP, constructed from eleven different U/Th-dated stalagmite δ18O records from Gunung Mulu National Park in northern Borneo. The reconstruction exhibits significant precessional power in phase with boreal fall insolation strength over the 0-160 ky BP period, identifying precessional insolation forcing as the dominant driver of hydroclimate variability in northern Borneo on orbital timescales. A comparison with a network of paleoclimate records from the circum-Pacific suggests the insolation sensitivity may arise from changes in the Walker circulation system. Distinct millennial-scale increases in stalagmite δ18O, indicative of reduced regional convection, occur within glacial terminations and may reflect a response to shifts in inter-hemispheric temperature gradients. Our results imply that hydroclimate in this region is sensitive to external forcing, with a response dominated by large-scale temperature gradients.

  10. The stress-coping (mis)match hypothesis for nature × nurture interactions.

    PubMed

    Homberg, Judith R

    2012-01-13

    There is high consensus that stress-related disorders like depression are shaped by nature×nurture interactions. However, the complexity appears larger than envisaged and nature×nurture research is progressing too slowly. An important reason is that mainstream research is focussing on the idea that a combination of genotypic stress-sensitivity and stress exposure inevitably leads to maladaptive stress-coping responses, and thereby stress-related disorders. However, stress-coping responses can also be adaptive and adhere to the expected norm. Here I elaborate the 'environment' mismatch hypothesis proposed by Mathias Schmidt (Psychoneuroendocrinology, 36, 330-338, 2011) to the stress-coping (mis)match (SCM) hypothesis postulating that stress-coping responses-as programmed by nature×age-dependent nurture interactions-are adaptive when they match current stress conditions, but maladaptive when they mismatch current stress conditions. For instance, acquisition of an active stress-coping response during nurture may lead to the programmed release of active coping responses in current life. This is adaptive when current stress is escapable, but maladaptive when current stress is inescapable, leading to agitation. A model par example for nature×nurture interactions is the serotonin transporter promoter polymorphism, which will be discussed in the framework of the SCM hypothesis. The potential role of the prefrontal-amygdala circuit and the therapeutic implications of the SCM hypothesis will also be discussed.

  11. Using Bones to Shape Stones: MIS 9 Bone Retouchers at Both Edges of the Mediterranean Sea

    PubMed Central

    Blasco, Ruth; Rosell, Jordi; Cuartero, Felipe; Fernández Peris, Josep; Gopher, Avi; Barkai, Ran

    2013-01-01

    A significant challenge in Prehistory is to understand the mechanisms involved in the behavioural evolution of human groups. The degree of technological and cultural development of prehistoric groups is assessed mainly through stone tools. However, other elements can provide valuable information as well. This paper presents two bone retouchers dated to the Middle Pleistocene MIS 9 used for the shaping of lithic artefacts. Originating from Bolomor Cave (Spain) and Qesem Cave (Israel), these two bone retouchers are among the earliest of the Old World. Although the emergence of such tools might be found in the latest phases of the Acheulean, their widespread use seems to coincide with independently emergent post-Acheulean cultural complexes at both ends of the Mediterranean Sea: the post-Acheulean/pre-Mousterian of Western Europe and the Acheulo Yabrudian Cultural Complex of the Levant. Both entities seem to reflect convergent processes that may be viewed in a wider cultural context as reflecting new technology-related behavioural patterns as well as new perceptions in stone tool manufacturing. PMID:24146928

  12. Early regional LGM (MIS 3) reflected in Central European Loess-Paleosol Sequences?

    NASA Astrophysics Data System (ADS)

    Zoeller, Ludwig; Fuchs, Markus

    2014-05-01

    The age of the "Brandenburg Phase", representing the regional LGM in Northern Germany and Poland, has been under debate. Evidence was found recently by OSL dating that it occurred during late MIS 3. In a new loess profile in the famous quarry of Nußloch south of Heidelberg (Germany) an exceptionally thick (6 m) loess-paleosol sequence (LPS) starts with a boreal brown soil regionally known as "Lohne soil", which terminates the Middle Pleniglacial LPS, according to classical stratigraphies. This paleosol is overlain by loess beds interbedding with weakly developed tundra-gley soils of typically Upper Pleniglacial habitus. Mean OSL ages from quartz fine and middle grains range between ca. 29 ka and ca. 35 ka in this part of the section which is much thicker than in previously studied corresponding parts of the loess stratigraphy at the Nußloch site. Our surprising dating results are, however, supported by recently dated loess beds in the Central European corridor between the ice margin of the Brandenburg Phase and the Northern Alpine LGM terminal moraines. Paleoenvironmental reconstructions point to cold but rather humid climatic conditions favouring rapid ice advance. We, thus, hypothesize that the rapid advance of Scandinavian ice into northern Central Europe which may have occurred ca. 10 ka prior to the global LGM, is reflected in some well-preserved Central European loess sections covering the last glacial cycle.

  13. Development of MisMatch Transmission Line (MMTL) system for ICH&CD test rig

    NASA Astrophysics Data System (ADS)

    Ajesh, P.; Jha, Akhil; Anand, Rohit; Harikrishna, JVS; Trivedi, Rajesh; Mukherjee, Aparajita

    2015-12-01

    India is responsible for delivery of 8+1(prototype) RF sources to ITER Organization. Each RF source will provide 2.5MW of RF power at 2 VSWR in the frequency range of 35 to 65MHz with other stringent specifications. To test the sources at full performance, India is developing unique 3MW test facility with variable load condition (up to VSWR 3.0 at any phase angle in between 0°-360°), consisting of high power 50 Ohm dummy load, phase shifter and stub. The combined assembly of phase shifter and stub is called MisMatch Transmission Line (MMTL) system. Detailed RF and thermal simulation of the MMTL system has been done as a part of developmental activity. Simulations predict maximum RF voltage and current in the MMTL system are 18kV and 400A, respectively. Thermal simulation shows that system can be operated at 1.7MW/CW/3VSWR without active cooling. A detailed design and initial test results of MMTL system considering RF & mechanical aspect for testing ITER ICRF sources is described in this paper.

  14. [Efficacy of the program "Testas's (mis)adventures" to promote the deep approach to learning].

    PubMed

    Rosário, Pedro; González-Pienda, Julio Antonio; Cerezo, Rebeca; Pinto, Ricardo; Ferreira, Pedro; Abilio, Lourenço; Paiva, Olimpia

    2010-11-01

    This paper provides information about the efficacy of a tutorial training program intended to enhance elementary fifth graders' study processes and foster their deep approaches to learning. The program "Testas's (mis)adventures" consists of a set of books in which Testas, a typical student, reveals and reflects upon his life experiences during school years. These life stories are nothing but an opportunity to present and train a wide range of learning strategies and self-regulatory processes, designed to insure students' deeper preparation for present and future learning challenges. The program has been developed along a school year, in a one hour weekly tutorial sessions. The training program had a semi-experimental design, included an experimental group (n=50) and a control one (n=50), and used pre- and posttest measures (learning strategies' declarative knowledge, learning approaches and academic achievement). Data suggest that the students enrolled in the training program, comparing with students in the control group, showed a significant improvement in their declarative knowledge of learning strategies and in their deep approach to learning, consequently lowering their use of a surface approach. In spite of this, in what concerns to academic achievement, no statistically significant differences have been found.

  15. MSV3d: database of human MisSense Variants mapped to 3D protein structure.

    PubMed

    Luu, Tien-Dao; Rusu, Alin-Mihai; Walter, Vincent; Ripp, Raymond; Moulinier, Luc; Muller, Jean; Toursel, Thierry; Thompson, Julie D; Poch, Olivier; Nguyen, Hoan

    2012-01-01

    The elucidation of the complex relationships linking genotypic and phenotypic variations to protein structure is a major challenge in the post-genomic era. We present MSV3d (Database of human MisSense Variants mapped to 3D protein structure), a new database that contains detailed annotation of missense variants of all human proteins (20 199 proteins). The multi-level characterization includes details of the physico-chemical changes induced by amino acid modification, as well as information related to the conservation of the mutated residue and its position relative to functional features in the available or predicted 3D model. Major releases of the database are automatically generated and updated regularly in line with the dbSNP (database of Single Nucleotide Polymorphism) and SwissVar releases, by exploiting the extensive Décrypthon computational grid resources. The database (http://decrypthon.igbmc.fr/msv3d) is easily accessible through a simple web interface coupled to a powerful query engine and a standard web service. The content is completely or partially downloadable in XML or flat file formats. Database URL: http://decrypthon.igbmc.fr/msv3d.

  16. The effect of absorption and coherent interference in the photoluminescence and electroluminescence spectra of SRO/SRN MIS capacitors.

    PubMed

    Juvert, Joan; González-Fernández, Alfredo Abelardo; Llobera, Andreu; Domínguez, Carlos

    2013-04-22

    In this paper we present a technique that can be used to study the effect of absorption and coherent interference in the luminescence of multilayer structures. We apply the technique to the measured photoluminescence and electroluminescence spectra of MIS capacitors where the insulator is composed of a silicon rich oxide (SRO)/silicon rich nitride (SRN) bilayer structure. We remove the effect of the multilayer stack on the measured photoluminescence spectrum of the samples without the metal contact to find the intrinsic spectrum. Then we apply the effect of the MIS structure on the intrinsic spectrum in order to calculate the electroluminescence spectrum. Good agreement with the experimentally measured EL spectrum is found. We discuss which parameters affect the spectra most significantly.

  17. A cold and fresh ocean surface in the Nordic Seas during MIS 11: Significance for the future ocean

    NASA Astrophysics Data System (ADS)

    Kandiano, Evgenia S.; Meer, Marcel T. J.; Bauch, Henning A.; Helmke, Jan; Damsté, Jaap S. Sinninghe; Schouten, Stefan

    2016-10-01

    Paleoceanographical studies of Marine Isotope Stage (MIS) 11 have revealed higher-than-present sea surface temperatures (SSTs) in the North Atlantic and in parts of the Arctic but lower-than-present SSTs in the Nordic Seas, the main throughflow area of warm water into the Arctic Ocean. We resolve this contradiction by complementing SST data based on planktic foraminiferal abundances with surface salinity changes using hydrogen isotopic compositions of alkenones in a core from the central Nordic Seas. The data indicate the prevalence of a relatively cold, low-salinity, surface water layer in the Nordic Seas during most of MIS 11. In spite of the low-density surface layer, which was kept buoyant by continuous melting of surrounding glaciers, warmer Atlantic water was still propagating northward at the subsurface thus maintaining meridional overturning circulation. This study can help to better constrain the impact of continuous melting of Greenland and Arctic ice on high-latitude ocean circulation and climate.

  18. High-elevation late Pleistocene (MIS 6-5) vertebrate faunas from the Ziegler Reservoir fossil site, Snowmass Village, Colorado

    NASA Astrophysics Data System (ADS)

    Sertich, Joseph J. W.; Stucky, Richard K.; McDonald, H. Gregory; Newton, Cody; Fisher, Daniel C.; Scott, Eric; Demboski, John R.; Lucking, Carol; McHorse, Brianna K.; Davis, Edward B.

    2014-11-01

    The vertebrate record at the Ziegler Reservoir fossil site (ZRFS) near Snowmass Village, Colorado ranges from ~ 140 to 77 ka, spanning all of Marine Oxygen Isotope Stage (MIS) 5. The site contains at least 52 taxa of macro- and microvertebrates, including one fish, three amphibian, four reptile, ten bird, and 34 mammal taxa. The most common vertebrate is Ambystoma tigrinum (tiger salamander), which is represented by > 22,000 elements representing the entire life cycle. The mastodon, Mammut americanum, is the most common mammal, and is documented by > 1800 skeletal elements making the ZRFS one of the largest accumulations of proboscidean remains in North America. Faunas at the ZRFS can be divided into two groups, a lake-margin group dating to ~ 140-100 ka that is dominated by woodland taxa, and a lake-center group dating to ~ 87-77 ka characterized by taxa favoring more open conditions. The change in faunal assemblages occurred between MIS 5c and 5a (vertebrates were absent from MIS 5b deposits), which were times of significant environmental change at the ZRFS. Furthermore, the ZRFS provides a well-dated occurrence of the extinct Bison latifrons, which has implications for the timing of the Rancholabrean Mammal Age in the region.

  19. Evidence of MIS 5 sea-level highstands in Gebel Mousa coast (Strait of Gibraltar, North of Africa)

    NASA Astrophysics Data System (ADS)

    Abad, M.; Rodríguez-Vidal, J.; Aboumaria, K.; Zaghloul, M. N.; Cáceres, L. M.; Ruiz, F.; Martínez-Aguirre, A.; Izquierdo, T.; Chamorro, S.

    2013-01-01

    The Last Interglacial is considered the most suitable episode from which to infer patterns of rapid sea-level change since its climatic conditions were similar to those of the present interglacial. However, specifying the true position of its sea level with high accuracy is very troublesome in the absence of sedimentological, erosional or even palaeontological markers. This study investigates the morphosedimentary evidence (beach deposits, cliff, notch and shore platform) of two highstands registered and dated during MIS 5 stage by U-series dating in the North of Morocco (Strait of Gibraltar). Bioerosive notches and mixed siliciclastic and carbonate deposits, high energy beaches with algal bioherms, were formed in coastal environments during MIS 5a. A sea-level height of + 10 m asl can be inferred for this substage. The record of MIS 5e substage is less defined in the geomorphological record, consisting of backshore/foreshore deposits located at + 13 to + 15 m asl. A tectonic uplift rate of ~ 0.1 mm/yr has been estimated for the last 130 kyr. These data are consistent with models of coastal uplifting calculated for the Strait of Gibraltar.

  20. Millennial-scale variations in western Sierra Nevada precipitation during the last glacial cycle MIS 4/3 transition

    NASA Astrophysics Data System (ADS)

    Oster, Jessica L.; Montañez, Isabel P.; Mertz-Kraus, Regina; Sharp, Warren D.; Stock, Greg M.; Spero, Howard J.; Tinsley, John; Zachos, James C.

    2014-07-01

    Dansgaard-Oeschger (D-O) cycles had far-reaching effects on Northern Hemisphere and tropical climate systems during the last glacial period, yet the climatic response to D-O cycles in western North America is controversial, especially prior to 55 ka. We document changes in precipitation along the western slope of the central Sierra Nevada during early Marine Oxygen Isotope Stages (MIS) 3 and 4 (55-67 ka) from a U-series dated speleothem record from McLean's Cave. The timing of our multi-proxy geochemical dataset is coeval with D-O interstadials (15-18) and stadials, including Heinrich Event 6. The McLean's Cave stalagmite indicates warmer and drier conditions during Greenland interstadials (GISs 15-18), signified by elevated δ18O, δ13C, reflectance, and trace element concentrations, and less radiogenic 87Sr/86Sr. Our record extends evidence of a strong linkage between high-latitude warming and reduced precipitation in western North America to early MIS 3 and MIS 4. This record shows that the linkage persists in diverse global climate states, and documents the nature of the climatic response in central California to Heinrich Event 6.

  1. Terrestrial environments during MIS 11: evidence from the Palaeolithic site at West Stow, Suffolk, UK

    NASA Astrophysics Data System (ADS)

    Preece, R. C.; Parfitt, S. A.; Bridgland, D. R.; Lewis, S. G.; Rowe, P. J.; Atkinson, T. C.; Candy, I.; Debenham, N. C.; Penkman, K. E. H.; Rhodes, E. J.; Schwenninger, J.-L.; Griffiths, H. I.; Whittaker, J. E.; Gleed-Owen, C.

    2007-05-01

    , although there is clear faunal evidence for climatic deterioration. Both the molluscan and vertebrate faunas suggest correlation of the interglacial sediments with the Hoxnian. Uranium series dates from the tufa (˜455 ka BP), TL dates from burnt flints (414±30 ka BP) and a range of amino acid racemization data all support correlation of this interglacial with MIS 11. However, four OSL dates from sand beneath the interglacial sequence yield a mean age of 261±31 ka BP, far younger than all other age determinations and far younger than implied by the biostratigraphy. Archaeologically the site is unusual in showing prolonged human occupation within closed deciduous forest and evidence for controlled use of fire in a Lower Palaeolithic context. Biostratigraphical correlations with other Lower Palaeolithic sites support the suggestion that Acheulian and Clactonian industries both occurred in southern Britain during the same substage of the Hoxnian, although not necessarily at precisely the same time. The characteristics of the MIS 11 interglacial in Britain are discussed in the light of evidence from Beeches Pit and elsewhere.

  2. Northern Cordilleran Ice Sheet Dynamics in Coastal Alaska from MIS 3 to the Present: Initial Results

    NASA Astrophysics Data System (ADS)

    Penkrot, M. L.; Jaeger, J. M.; LeVay, L.; St-Onge, G.; Mix, A. C.; Bahlburg, H.; Davies-Walczak, M.; Gulick, S. P. S.

    2014-12-01

    Establishing the timing of northwestern Cordilleran ice sheet (NCIS) advance-retreat cycles in southern Alaska allows for investigation of global synchronicity in glacial-age climate forcing. Integrated Ocean Drilling Program Expedition 341 targeted the glacial dynamics of the NCIS in the coastal St. Elias range. Sediment cores from Site U1419 encompass times of global ice advance and retreat from MIS 3 to the present, based on a preliminary age model with 5-kya resolution developed using oxygen isotopes from benthic and planktonic foraminifera and stratigraphic correlation with a previously C-14 dated site survey core (Davies et al., 2011; doi:10.1029/2010PA002051). CT images of cores were used to identify sedimentary facies and relative ice sheet proximity. Six sedimentary facies were identified in the images; massive mud with and without lonestones, laminations with and without lonestones, massive and stratified diamict (>1 clast/cm). Elemental scanning XRF data were used to delineate possible downcore changes in sediment provenance using provenance-sensitive transition metals. Diamict and gravelly mud are the most common facies, indicative of persistent glacial input interpreted as marine-terminating glacial systems. Stratified diamicts are interpreted as periods of maximum ice extent (~18-20 ka), whereas massive mud (~14 ka-present) suggests terminus retreat. Intervals of laminated mud with and without lonestones are interpreted as periods of reduced ice cover, with the most recent (~14.5 kya) coinciding with the Bølling Interstade of northern Europe/Greenland (Davies et al., 2011). Downcore changes in Al-normalized metal XRF counts vary along with sedimentary lithoficies, suggesting changes in sediment provenance that may be related to the quantity of glacigenic sediment delivery to this location.

  3. Large shifts in vegetation and climate during the Early Weichselian (MIS 5d-c) inferred from multi-proxy evidence at Sokli (northern Finland)

    NASA Astrophysics Data System (ADS)

    Helmens, Karin F.; Väliranta, Minna; Engels, Stefan; Shala, Shyhrete

    2012-05-01

    For decades, detailed studies on Early Weichselian deposits have been made in central Europe. In contrast, these studies are rare in Fennoscandia in northern Europe. We here integrate an extensive multi-proxy data set obtained on sediments of MIS 5d-c age that form part of a long sediment record preserved at Sokli in northern Finland. We make a detailed interpretation of the vegetation and depositional history for MIS 5d-c using pollen, macrofossils, diatoms and other siliceous microfossils, insect remains, and sediment characteristics, and combine these data with recently published estimates on July temperatures based on chironomids and selected plant indicator species in order to make inferences of paleo-climate regimes. The fossil record obtained on the seven meter thick MIS 5d-c deposit at Sokli is exceptionally rich in species due to the large variety of habitats associated with an overall fluvial depositional environment. A braided river system flanked by steppe-tundra vegetation is inferred for MIS 5d. Mean July temperatures of at least 12-14 °C are indicated by chironomids and plant indicator species and are in agreement with the presence of conifers and birch trees as recorded by macrofossils. The reconstructed environmental conditions suggest strong continental climate conditions at Sokli during MIS 5d. The gradual infilling of an oxbow lake and subsequent return to stream channel deposition is traced in great detail in the overlying gyttja and gravelly sediment of MIS 5c age. The terrestrial pollen and plant macrofossil record from the gyttja shows the establishment of birch forest followed by the spread of pine and then spruce. Rich plant indicator species assemblages indicate that the boreal environment at Sokli during MIS 5c experienced July temperatures several degrees higher than the present-day value of 13 °C. The high summer temperatures and presence of larch suggest more continental conditions. More open vegetation returned at Sokli during late

  4. Coupled Warming and Drought in the American Southwest During Long mid-Pleistocene Interglacials (MIS 11 and 13)

    NASA Astrophysics Data System (ADS)

    Fawcett, P. J.; Werne, J.; Anderson, R.; Heikoop, J.; Brown, E.; Hurley, L.; Smith, S.; Berke, M.; Soltow, H.; Goff, F.; Geissman, J.; Woldegabriel, G.; Fessenden, J.; Cisneros-Dozal, M.; Allen, C. D.

    2008-12-01

    An 82-m deep lacustrine sediment core from the Valles Caldera, northern New Mexico reveals details of climate change over two glacial cycles in the middle Pleistocene. Core VC-3, taken from the Valle Grande, has a basal 40Ar/39Ar date of 552 kyr from a tephra associated with the eruption of the South Mountain rhyolite which formed the lake. A variety of proxies including core sedimentology, organic carbon and carbon isotopic ratios, pollen, scanning XRF analysis and a new paleotemperature proxy, MBT (methylated branched tetraether) content of soil bacteria reveal two major warm periods above the basal tephra which we correlate with interglacials MIS 13 and MIS 11. This chronology is corroborated by the identification of two geomagnetic field "events" which are correlated with globally recognized events (14α and 11α). The lacustrine record terminates at ~350 ka when the lake filled its available accommodation space behind the dam of rhyolite lava. MBT temperature estimates show average glacial temperatures in core VC-3 of ~ -4°C, and average interglacial temperatures of ~ +4°C, and the general trends are well corroborated by multiple proxies including pollen and lacustrine organic productivity estimates. A temperature increase of ~9°C occurs during Termination V, the largest glacial termination in the Pleistocene. Multiple proxies from VC-3 show significant structure during the two interglacials present in the core (MIS 13 and 11). Three warm substages (~ 2°C warmer) are recognized within MIS 11 based on organic productivity (Corg, Si/Ti ratios), pollen taxa, elevated charcoal from fires, and the MBT temperature estimates. These warm substages appear to be a strong response to precessional forcing in the SW continental interior even though the amplitude of eccentricity-modulated precession was at a minimum during MIS 11. These results suggest that future climate change in the SW may be characterized by similar natural temperature variability on precessional

  5. Changes in Organic Carbon Accumulation and Benthic Foraminiferal Assemblages in Sediments Deposited on the Bermuda Rise (odp Site 1063)DURING Mis 13 TO 10

    NASA Astrophysics Data System (ADS)

    Poli, M.; Meyers, P. A.; Thunell, R.; Capodivacca, M.

    2011-12-01

    We determined organic carbon concentrations, organic matter carbon and nitrogen isotopic compositions, and benthic foraminiferal assemblages in sediments deposited between ~500-340 ka at ODP Site 1063 on the northeastern flank of the Bermuda Rise to identify the nature of glacial-interglacial changes in this part of the North Atlantic. This time interval includes Marine Isotope Stage (MIS) 11, a particularly warm and long interglacial that was similar to today, and MIS 12, one of the most severe glacials of the last 600 ky. Higher organic carbon accumulation rates occurred during MIS 12 and 10 (up to 3.7 g m-2 yr-1), in correspondence with the highest sedimentation rates (33-36 cm/ky). This pattern suggests a combination of enhanced production and improved preservation of organic matter at these glacial times. Organic δ13C values are larger during MIS 12 and MIS 10 (~-22.5%) than during MIS 11.3 (~-25%), which is consistent with greater glacial-stage marine productivity. At the same time, smaller glacial-stage δ15N values (~3.5%) indicate diminished denitrification, which suggests better oceanic mixing at this location. Benthic foraminiferal assemblages are dominated by Nuttallides umbonifera during MIS 11.3, a species adapted to oligotrophic environments, and by Oridorsalis umbonatus during glacial intervals, a cosmopolitan taxon that dwells under a wide range of environmental conditions and probably prefers a low but sustained flux of highly degraded organic material. The beginnings of the MIS 10 and MIS 12 glaciations are characterized by large and rapid fluctuations in the abundance of Epistominella exigua, a species that inhabits seasonally deposited aggregates of phytodetritus produced during spring plankton blooms, thus suggesting a marked increase in local primary productivity at these times. We conclude that two kinds of glacial-interglacial changes affected delivery of organic matter to the sediments of Site 1063 - a southward shift of the Gulf Stream

  6. Cosmogenic 10Be and 26Al exposure ages of glaciations in the Frankland Range, southwest Tasmania reveal a limited MIS-2 ice advance

    NASA Astrophysics Data System (ADS)

    Kiernan, Kevin; Fink, David; McConnell, Anne

    2017-02-01

    New mapping of the glacial geomorphology coupled with 10Be and 26Al exposure age dating of moraines on the flanks of the Frankland Range in south west Tasmania indicate that glacier extent during MIS-2 was far smaller than during earlier glaciations with the ice cover being confined to only the uppermost cirques of the range. Moraines further down the range flanks, ∼50-150 m lower in altitude than the MIS-2 dated advance, indicate that glaciers were only slightly larger during earlier glaciations and, depending on the interpretation of their exposure ages, may range from MIS 7 to MIS 12. These older moraines are nested inside the maximum ice limits of an even more ancient and extensive glaciation, defined by degraded valley floor moraines and coalescing glacio-fluvial fans that remain undated but appear no younger than MIS 12. Patterns of glacial erosion and moraine deposition on the Frankland Range suggest that the more recent glaciations were increasingly influenced by the erosional morphology initiated by earlier glaciers. Microclimatic differences resulting from this earlier glacial topography were particularly influential determinants of glaciation during MIS 2. These results are consistent with emerging evidence from studies of other ranges in southwest Tasmania.

  7. Very fast Uplifting in the Kongur Shan, NE Pamir during Marine Isotope Stage 5 (MIS 5)

    NASA Astrophysics Data System (ADS)

    Chen, J.; Liu, C.; Qin, J.; Yang, H.; Luo, M.; Huang, M.; Li, W.

    2014-12-01

    inflection points on ESR Al center age-elevation plots, the apparent exhumation rate increased to ~22 mm/a around ~75 ka, might be caused by a mix of enhanced fluvial and glacial erosion, normal faulting and bulk exhumation during MIS 5.

  8. Timing and Rate of Deglaciation of the MIS 2 Cordilleran Ice Sheet in Yukon Territory

    NASA Astrophysics Data System (ADS)

    Ward, B. C.; Bond, J. D.; Gosse, J. C.; Turner, D. G.

    2015-12-01

    The northern Cordilleran ice sheet (CIS) consisted of a series of quasi-independent ice lobes that coalesced during the last glacial maximum (LGM) to form a continuous carapace of precipitation limited ice over southern Yukon. Variations in effective precipitation to different source areas of these ice lobes have been used to explain disparities in glacier extents in marine oxygen isotope stages (MIS) 4 and 6. Deglaciation of the northern margin of the CIS and its rate of recession from the LGM are poorly understood. We use cosmogenic nuclide exposure dating (10Be and 36Cl) on groups of 3-4 glacial erratics to reconstruct the timing and rate of deglaciation. Our sampling concentrated on the St. Elias, Cassiar and Selwyn lobes, as well an independent glacier from the Ogilvie Mountains. Boulders sampled up-ice from terminal moraines show that the initiation of deglaciation varied regionally. 36Cl ages from the Ogilvie Mountains indicate that deglaciation initiated by 24.8 ka. Further south in the Selwyn Lobe, two sites separated by ~150 km returned ages of 15.2 and 16.1 ka. To the south-west, three boulders from the Cassiar Lobe are 13.6 ka. Rates of deglaciation are best constrained for the Cassiar Lobe with two transects along different flow lines. Multiple valley bottom samples in the mid-deglaciation setting at Whitehorse yielded ages of 12.0 ka, while one boulder from the adjacent ridge top 600 m above is 13.5 ka. In the accumulation zone, ice-free conditions occurred by 10.8 ka. The other transect has higher elevation samples in a mid-deglaciation setting in the Pelly Mountains that indicate deglaciation occurred by 13.0 ka. Samples taken from high elevation and valley bottom sites close to accumulation zones of the Cassiar Lobe yielded ages of 13.6 and 11.0 ka, respectively. These results provide a chronology for the style of deglaciation interpreted from regional mapping throughout Yukon: gradual initial retreat and thinning marked by moraines, followed by

  9. High-resolution vegetation dynamics reconstitution in the Zaire/Congo watershed since MIS 6

    NASA Astrophysics Data System (ADS)

    Dalibard, Mathieu; Popescu, Speranta-Maria; Maley, Jean; Pittet, Bernard; Marsset, Tania; Baudin, François; Dennielou, Bernard; Sionneau, Thomas; Escarguel, Gilles; Droz, Laurence

    2010-05-01

    contemporaneously with a significant presence of afromontane forest in MIS 6 may be correlated with rainfall increase probably related to changes in the monsoon activity. The information in term of humidity obtained from some other proxies (clay mineralogy, organic carbon, and elemental ratio measured by XRF, such as Br, etc.) shows a similar trend with the pollen record. A spectral analysis has been performed and reveals that the reconstructed climatic parameters from the Zaire/Congo watershed correlated with Milankovitch cycles, including semi-precession cycles (10 kyrs) characteristic of the Equatorial zone.

  10. MIS 3 Climate Variability Revealed by Two Stalagmites from Northern and South-Western Romania

    NASA Astrophysics Data System (ADS)

    Dragusin, V.; Hoffmann, D.; Onac, B. P.; Isverceanu, E.

    2011-12-01

    We present two stable isotope records of climate variability from stalagmites in northern (#1152 from Pestera Izvorul Tausoarelor, Rodna Mountains) and south-western (#POM1 from Pestera Ascunsa, Mehedinti Mountains) Romania. Both cave entrances are located at over 1000 m asl in areas covered by mature beech forests, in continental temperate climate. Superimposed on the present-day climatic conditions are two different climate influences: Atlantic in the north and sub-mediterranean in the south-west. Both stalagmites were dated by means of uranium series on a Thermo Neptune MC-ICP-MS at Centro Nacional de Investigacion sobre la Evolucion Humana (Burgos, Spain) and samples for stable O and C stable isotopes were analysed on a Thermo Delta V IRMS at the Stable Isotope Laboratory, University of South Florida. For the stable isotopes profile, stalagmite 1152 was sampled at an average interval of 100 years , whereas POM1 was sampled at a 30 years interval. The two stalagmites reveal differences in isotopic signature response to climatic variability. When the POM1 δ18O profile is compared to the NGRIP δ18O, a lower variability of its values is evident. Even so, we are still able to distinguish structures similar to Greenland Interstadials (GIs) 7 and 8, the latter being composed of two distinct units. The stalagmite 1152 δ18O profile shows less variability although some of the peaks in the values could be correlated to GIs 4 through 12. The absolute values of these two records vary around an average of -7.5%, very close to the typical Holocene values from this part of Europe. This may point to an enhanced Mediterranean circulation towards the north during MIS 3. In return, the δ13C values of the two stalagmites are very different and point to large differences in the activity of plants and soil organisms. POM1 values, averaging -5 to -6%, indicate a C4 type vegetation in the area above the cave, that could belong to alpine meadows. This may document a lowering of the

  11. Geochronologic evidence for a possible MIS-11 emergent barrier/beach-ridge in southeastern Georgia, USA

    NASA Astrophysics Data System (ADS)

    Markewich, H. W.; Pavich, M. J.; Schultz, A. P.; Mahan, S. A.; Aleman-Gonzalez, W. B.; Bierman, P. R.

    2013-01-01

    ˜450 ka to >1 Ma. The age and geomorphic data for Georgia and South Carolina possibly suggest the presence of MIS-11 (˜420-360 ka) shoreline deposits between 15 m and 28 m above present sea level in the Southeastern Atlantic Coastal Plain.

  12. Geochronologic evidence for a possible MIS-11 emergent barrier/beach-ridge in southeastern Georgia, USA

    USGS Publications Warehouse

    Markewich, H.W.; Pavich, M.J.; Schultz, A.P.; Mahan, S.A.; Aleman-Gonzalez, W. B.; Bierman, P.R.

    2013-01-01

    ~450 ka to >1 Ma. The age and geomorphic data for Georgia and South Carolina possibly suggest the presence of MIS-11 (~420−360 ka) shoreline deposits between 15 m and 28 m above present sea level in the Southeastern Atlantic Coastal Plain.

  13. A review of the MIS 5e highstand deposits from Santa Maria Island (Azores, NE Atlantic): palaeobiodiversity, palaeoecology and palaeobiogeography

    NASA Astrophysics Data System (ADS)

    Ávila, Sérgio P.; Melo, Carlos; Silva, Luís; Ramalho, Ricardo S.; Quartau, Rui; Hipólito, Ana; Cordeiro, Ricardo; Rebelo, Ana Cristina; Madeira, Patrícia; Rovere, Alessio; Hearty, Paul J.; Henriques, Diamantino; Silva, Carlos Marques da; Martins, António M. de Frias; Zazo, Caridad

    2015-04-01

    The privileged location of Santa Maria Island (Azores archipelago) in the middle of the North Atlantic makes the fossiliferous outcrops on this island of utmost importance to gain a better understanding of how coeval living communities relate to the broader evolutionary and biogeographic history of the Atlantic basin during the late Neogene and the Quaternary. Here we focus on this island's MIS 5e fossil record, offering a comprehensive review on the palaeobiodiversity, palaeoecology and palaeobiogeography of the biota living in the mid North Atlantic during this interglacial. Several studies in oceanic islands stress the huge impact of sea level changes on insular communities. Pleistocene sea-level changes occur during the short-time events known as "Terminations" (associated to glacial/interglacial shifts) as well as with the onset of glaciations (associated to interglacial/glacial shifts). Both are responsible for extinctions and local disappearance of species, bottleneck effects and formation of new species, resulting in community structure changes. This work increases the number of fossil marine taxa reported from the Last Interglacial deposits of Santa Maria to 143 species. All the 19 new records are molluscs (13 gastropods and 6 bivalves), thus increasing the number of fossil molluscs to 136 species. Although thermophilic members of the "Senegalese" tropical fauna were found in these deposits, many of the most emblematic species (e.g., Persististrombus latus (=Strombus bubonius), Cymbula safiana, Harpa doris, Cardita senegalensis, Barbatia plicata, Ctena eburnea or Hyotissa hyotis) are absent, suggesting that they did not reach the Azores. Our results indicate that the main differences between the species composition of the MIS 5e and the present-day shallow-water Azorean communities are probably due to the dropping of sea surface temperature associated with the onset of the last glaciation, which had both direct and indirect effects on species ecology. A

  14. Human occupation of the Arabian Empty Quarter during MIS 5: evidence from Mundafan Al-Buhayrah, Saudi Arabia

    NASA Astrophysics Data System (ADS)

    Groucutt, Huw S.; White, Tom S.; Clark-Balzan, Laine; Parton, Ash; Crassard, Rémy; Shipton, Ceri; Jennings, Richard P.; Parker, Adrian G.; Breeze, Paul S.; Scerri, Eleanor M. L.; Alsharekh, Abdullah; Petraglia, Michael D.

    2015-07-01

    The Empty Quarter (or Rub' al Khali) of the Arabian Peninsula is the largest continuous sandy desert in the world. It has been known for several decades that Late Pleistocene and Holocene deposits, representing phases of wetter climate, are preserved there. These sequences have yielded palaeontological evidence in the form of a variety of vertebrate and invertebrate fossils and have been dated using various radiometric techniques. However, evidence for human presence during these wetter phases has until now been ephemeral. Here, we report on the first stratified and dated archaeology from the Empty Quarter, recovered from the site of Mundafan Al-Buhayrah (MDF-61). Human occupation at the site, represented by stone tools, has been dated to the later part of Marine Isotope Stage (MIS) 5 using multiple luminescence dating techniques (multigrain and single grain OSL, TT-OSL). The sequence consists primarily of lacustrine and palustrine sediments, from which evidence for changing local environmental conditions has been obtained through analysis of fossil assemblages (phytoliths and non-marine molluscs and ostracods). The discovery of securely-dated archaeological material at ∼100 to 80 ka in the Empty Quarter has important implications for hypotheses concerning the timing and routes of dispersal of Homo sapiens out of Africa, which have been much debated. Consequently, the data presented here fill a crucial gap in palaeoenvironmental and archaeological understanding of the southern Arabian interior. Fossils of H. sapiens in the Levant, also dated to MIS 5, together with Middle Palaeolithic archaeological sites in Arabia and India are thought to represent the earliest dispersal of our species out of Africa. We suggest that the widespread occurrence of similar lithic technologies across southern Asia, coupled with a growing body of evidence for environmental amelioration across the Saharo-Arabian belt, indicates that occupation of the Levant by H. sapiens during MIS 5

  15. Deep intronic mis-splicing mutation in JAK3 gene underlies T-B+NK- severe combined immunodeficiency phenotype.

    PubMed

    Stepensky, Polina; Keller, Baerbel; Shamriz, Oded; NaserEddin, Adeeb; Rumman, Nisreen; Weintraub, Michael; Warnatz, Klaus; Elpeleg, Orly; Barak, Yaacov

    2016-02-01

    Severe combined immune deficiency (SCID) is a group of genetically heterogeneous diseases caused by an early block in T cell differentiation and present with life threatening infections, often within the first year of life. Janus kinase (JAK)3 gene mutations have been found to cause autosomal recessive T-B+ SCID phenotype. In this study we describe three patients with a novel deep intronic mis-splicing mutation in JAK3 as a cause of T-B+NK- SCID highlighting the need for careful evaluation of intronic regulatory elements of known genes associated with clearly defined clinical phenotypes. We present the cases and discuss the current literature.

  16. Electrical Characteristics of Ni-CNT-SiO2-SiC Structured 4H-SiC MIS Capacitors.

    PubMed

    Lee, Taeseop; Kang, Min-Seok; Ha, Tae-Jun; Koo, Sang-Mo

    2015-10-01

    In this study, the electrical characteristics of Ni-CNT-SiO2-SiC structured 4H-SiC MIS capacitors were investigated. The effect of CNTs in the gate/insulator interface have been characterized by C-V measurement at 300 to 500K and J-V have also been measured. The experimental flat-band voltage tends to change with or without CNTs. Current densities of both devices are observed a negligible difference up to 3 V. It has been found that adding CNTs and/or change of temperature can help to control the positive and/or negative flat-band voltage shift.

  17. MIS M2 initiation and termination link to the shallow CAS open and close?

    NASA Astrophysics Data System (ADS)

    Tan, Ning; Ramstein, Gilles; Dumas, Christophe; Contoux, Camille

    2016-04-01

    The Marine Isotope Stage M2 (3.264 -3.312 Ma) occurred just prior to the well documented warm mid-Pliocene (mPWP). With a 0.5‰ benthic foraminiferal δ180 shift (Lisiecki and Raymo, 2005), MIS M2 is thought to be a glacial comparable period associated with huge but uncertain sea-level records of 20-60m below present levels (Naish et al. 2009; Miller et al. 2012; Dwyer et al. 2009). However, the mechanism of M2 initiation and termination are still an enigma, since CO2 records were relatively higher than the Quaternary glaciation period and the minima summer insolation during M2 was stronger than other glacial periods. By inferring from data records, De Schepper (2013) proposed that the shallow open Central American Seaway (CAS) observed during M2 could play as a trigger in M2 initiation, then the closure of this shallow CAS resulted from M2 large ice sheet build-up terminates this glacial period. But this assumption has not been test by the model. In this study, we apply IPSL-CM5A Atmosphere-Ocean coupled General Circulation Model (AOGCM) and GRISLI ice sheet model to investigate mechanisms of M2 initiation and termination. We firstly investigate the role of "shallow open CAS" (De Schepper et al. 2013) on M2 initiation. In the mean time we also take into account the main forcing during M2, which includes astronomical parameters, Greenhouse gases and vegetation. Our results show that shallow open CAS plays an important role in reducing northward heat transport in Atlantic low latitudes by 0.05 - 0.1 PW, but it is not a key factor in NH ice sheet build-up; Astronomical parameters and CO2 concentration are essential to create a basic global cooling environment for M2 (cooling by ~3.65 K than mPWP); Cold vegetation replacement amplifies the cooling in north high latitudes by ~ 8 K, which finally allows large ice sheet building up in Northern Hemisphere (12.25 m sea level drop is simulated with considering ice sheet feedback on the climate). The simulated ice sheet

  18. A climate model study of an intense Asian Monsoon in a La Niña-like climate of MIS-13

    NASA Astrophysics Data System (ADS)

    Karami, M. P.; Berger, A.; Herold, N.; Yin, Q. Z.

    2012-04-01

    Studying the paleo-monsoon during past interglacials is a valuable approach to improve our understanding of the monsoon system in present-day and future climates. We focus on Marine Isotopic stage 13 (MIS-13; ~0.5 Ma) which was a relatively cool interglacial, but with a paradoxically intense monsoonal precipitation over eastern and southern Asia. Our main goal is to understand the physics-based mechanism driving the intense monsoon, specifically the East Asian Summer Monsoon (EASM), during MIS-13. We applied both an intermediate complexity model (LOVECLIM) as well as fully coupled general circulation models (HadCM3 and CCSM3) to simulate pre-industrial and MIS-13 climates. The boundary conditions for MIS-13 were chosen for 506 ka with Northern-Hemisphere (NH) summer at perihelion and a CO2 concentration of 240 ppm. For pre-industrial, NH-winter occurring at perihelion and a CO2 concentration of 280 ppm were prescribed. Preliminary analysis of the model results shows different atmospheric and oceanic features in MIS-13 compared to the pre-industrial which could affect the EASM. The Northern Pacific Subtropical High (NPSH), which is an important factor in controlling the EASM, strengthened and extended to the northwest in MIS-13 partially due to cooling of the central Pacific Ocean. This in turn brought more moisture from the Central Pacific to the EASM-region and caused a northwestward shift and bending of the low-level jet along East Asia. The change in the low-level jet subsequently increased the meridional wind velocity at 850 mbar in the EASM-region providing more moisture from the tropical Pacific and Indian Oceans. In addition, higher sea-surface temperature in the Indian Ocean during MIS-13 further increased the source of moisture for the EASM. The Asian low, which is another component of the EASM-system, also shifted eastward moving the rain band northward. Moreover, it was found that MIS-13 had a dominant La Niña condition in the tropical Pacific. La Ni

  19. Insights into MIS 3 and 4 climate in the Alps from the Baumkirchen paleo-lake site: Results of pollen analysis

    NASA Astrophysics Data System (ADS)

    Barrett, Samuel; Drescher-Schneider, Ruth; Starnberger, Reinhard; Spötl, Christoph

    2016-04-01

    The well-known Baumkirchen site of western Austria has recently been the focus of a renewed research effort. New drilling has greatly extended the length of the known lacustrine sequence to over 250 m. Luminescence dating has corroborated the late MIS 3 radiocarbon dates for the upper part of the sequence and revealed two lake phases: the upper extending from late MIS 3 back to mid MIS 3, and the lower covering late MIS 4 or early MIS 3 back possibly as far as MIS 5a. X-ray fluorescence core scanning analysis confirmed the presence of two phases which have different geochemical signals, and provided a chemistry-based stratigraphy in the visually monotonous sediments. In these uniform sediments, the only clear indication of climatic conditions from the sediments themselves is a short sequence of ice-rafted debris corresponding to the end of MIS 4. However, given their age and location within the Alps, these sediments provide an important archive of Alpine climate in the last glacial cycle. We present new results from pollen analysis and discuss them in the context of previously reported findings. Due to high sedimentation rates, pollen counts were very low. However, two stadials and two interstadials were identified. The entire lower lake phase corresponding to MIS 4 was identified as a stadial, being characterised by a very low total pollen concentrations, a dominance of herb over tree pollen and significant reworking of pre-Quaternary forms and wood fragments. The upper lake phase contains two interstadials split by an intervening stadial. The interstadials are characterised by higher total pollen concentrations and proportion of woody species including the sporadic presence of relatively warm climate species with the upper of the two appearing better developed with these indicators more strongly expressed. This upper interstadial corresponds to the location of well dated plant remains putting its age around 35 ka cal BP, strongly suggesting a correlation to

  20. Fluctuations of Mediterranean Outflow Water circulation in the Gulf of Cadiz during MIS 5 to 7: Evidence from benthic foraminiferal assemblage and stable isotope records

    NASA Astrophysics Data System (ADS)

    Singh, A. D.; Rai, A. K.; Tiwari, M.; Naidu, P. D.; Verma, K.; Chaturvedi, M.; Niyogi, A.; Pandey, D.

    2015-10-01

    We studied variations in benthic foraminiferal assemblages and δ13C for the last 225 kyr at IODP site U1387 which is currently bathed by upper core of the Mediterranean Outflow Water (MOW). The MOW paleocirculation and sea-floor environment (oxygen level, trophic condition, bottom current strength) have been inferred from faunal composition; species diversity, abundances of selected index species/groups, microhabitat preferences combined with δ13C record of the epifaunal Cibicidoides pachyderma. The faunal and isotope records indicate relatively better ventilation at sea-floor and low trophic condition during MIS 1, 5 and 7 possibly due to increased influence of upper MOW in the Gulf of Cadiz. Our multi-proxy record reflects significant and rapid changes during cold (stadial) and warm (interstadial) phases within the interglacials MIS 5 and 7 and at Termination II. The faunal and isotope records reveal strong MOW flow and better ventilated, oligotrophic bottom-water conditions during stadials MIS 5b, 5d, 7b and 7d. The study further demonstrates weakened MOW intensity associated with poor ventilation and increased trophic level at sea-floor during interstadials MIS 5a, 5e, 7a and 7c. MOW flow was relatively sluggish at Termination II, followed by its strengthening at the end of MIS 5e. The chronology of these events suggests that periods of weakened MOW correlate with sapropel layers of the Mediterranean Sea, implying strong coupling between glacial-interglacial climate and MOW circulation in the Gulf of Cadiz.

  1. Climate and hydrology of the last interglaciation (MIS 5) in Owens Basin, California: Isotopic and geochemical evidence from core OL-92

    USGS Publications Warehouse

    Li, H.-C.; Bischoff, J.L.; Ku, T.-L.; Zhu, Z.-Y.

    2004-01-01

    ??18O, ??13C, total organic carbon, total inorganic carbon, and acid-leachable Li, Mg and Sr concentrations on 443 samples from 32 to 83 m depth in Owens Lake core OL-92 were analyzed to study the climatic and hydrological conditions between 60 and 155 ka with a resolution of ???200 a. The multi-proxy data show that Owens Lake overflowed during wet/cold conditions of marine isotope stages (MIS) 4, 5b and 6, and was closed during the dry/warm conditions of MIS 5a, c and e. The lake partially overflowed during MIS 5d. Our age model places the MIS 4/5 boundary at ca 72.5 ka and the MIS 5/6 boundary (Termination II) at ca 140 ka, agreeing with the Devils Hole chronology. The diametrical precipitation intensities between the Great Basin (cold/wet) and eastern China (cold/dry) on Milankovitch time scales imply a climatic teleconnection across the Pacific. It also probably reflects the effect of high-latitude ice sheets on the southward shifts of both the summer monsoon frontal zone in eastern Asia and the polar jet stream in western North America during glacial periods. ?? 2003 Elsevier Ltd. All rights reserved.

  2. MIS and MFIS Devices: DyScO3 as a gate-oxide and buffer-layer

    NASA Astrophysics Data System (ADS)

    Melgarejo, R.; Karan, N. K.; Saavedra-Arias, J.; Pradhan, D. K.; Thomas, R.; Katiyar, R. S.

    2008-03-01

    Metal-Ferroelectric-Insulator-Semiconductor (MFIS) structure is of importance in nonvolatile memories, as insulating buffer layer that prevents interdiffusion between the ferroelectric (FE) and the Si substrate. However, insulating layer has some disadvantages viz. generation of depolarization field in FE film and increase of operation voltage. To overcome this, it is important to find a FE with low ɛr (compared to normal FE) and an insulating buffer layer with high ɛr (compared to ɛr = 3.9 of SiO2). High-k materials viz. LaAlO3, SiN, HfO2, HfAlO etc. have been studied as buffer layers in the MFIS structures and as gate-oxide in metal-insulator-silicon (MIS). Recently, a novel gate dielectric material, DyScO3 was considered and studies indicate that crystallization temperature significantly increased and the film on Si remained amorphous even at 1000 C annealing. Considering the requirements on crystallization temperature, ɛr, electrical stability for high-k buffer layers, DyScO3 seems to be very promising for future MFIS device applications. Therefore, the evaluations of MOCVD grown DyScO3 as gate-oxide for MIS and the buffer layers for Bi3.25La0.75Ti3O12 based MFIS structures are presented.

  3. The use of a virtual reality simulator to explore and understand the impact of Linac mis-calibrations

    NASA Astrophysics Data System (ADS)

    Beavis, Andrew W.; Ward, James W.

    2014-03-01

    Purpose: In recent years there has been interest in using Computer Simulation within Medical training. The VERT (Virtual Environment for Radiotherapy Training) system is a Flight Simulator for Radiation Oncology professionals, wherein fundamental concepts, techniques and problematic scenarios can be safely investigated. Methods: The system provides detailed simulations of several Linacs and the ability to display DICOM treatment plans. Patients can be mis-positioned with 'set-up errors' which can be explored visually, dosimetrically and using IGRT. Similarly, a variety of Linac calibration and configuration parameters can be altered manually or randomly via controlled errors in the simulated 3D Linac and its component parts. The implication of these can be investigated by following through a treatment scenario or using QC devices available within a Physics software module. Results: One resultant exercise is a systematic mis-calibration of 'lateral laser height' by 2mm. The offset in patient alignment is easily identified using IGRT and once corrected by reference to the 'in-room monitor'. The dosimetric implication is demonstrated to be 0.4% by setting a dosimetry phantom by the lasers (and ignoring TSD information). Finally, the need for recalibration can be shown by the Laser Alignment Phantom or by reference to the front pointer. Conclusions: The VERT system provides a realistic environment for training and enhancing understanding of radiotherapy concepts and techniques. Linac error conditions can be explored in this context and valuable experience gained in a controlled manner in a compressed period of time.

  4. Early Wisconsinan (MIS 4) Arctic ground squirrel middens and a squirrel-eye-view of the mammoth-steppe

    NASA Astrophysics Data System (ADS)

    Zazula, Grant D.; Froese, Duane G.; Elias, Scott A.; Kuzmina, Svetlana; Mathewes, Rolf W.

    2011-08-01

    Fossil arctic ground squirrel ( Spermophilus parryii) middens were recovered from ice-rich loess sediments in association with Sheep Creek-Klondike and Dominion Creek tephras (ca 80 ka) exposed in west-central Yukon. These middens provide plant and insect macrofossil evidence for a steppe-tundra ecosystem during the Early Wisconsinan (MIS 4) glacial interval. Midden plant and insect macrofossil data are compared with those previously published for Late Wisconsinan middens dating to ˜25-29 14C ka BP (MIS 3/2) from the region. Although multivariate statistical comparisons suggest differences between the relative abundances of plant macrofossils, the co-occurrence of steppe-tundra plants and insects (e.g., Elymus trachycaulus, Kobresia myosuroides, Artemisia frigida, Phlox hoodii, Connatichela artemisiae) provides evidence for successive reestablishment of the zonal steppe-tundra habitats during cold stages of the Late Pleistocene. Arctic ground squirrels were well adapted to the cold, arid climates, steppe-tundra vegetation and well-drained loessal soils that characterize cold stages of Late Pleistocene Beringia. These glacial conditions enabled arctic ground squirrel populations to expand their range to the interior regions of Alaska and Yukon, including the Klondike, where they are absent today. Arctic ground squirrels have endured numerous Quaternary climate oscillations by retracting populations to disjunct "interglacial refugia" during warm interglacial periods (e.g., south-facing steppe slopes, well-drained arctic and alpine tundra areas) and expanding their distribution across the mammoth-steppe biome during cold, arid glacial intervals.

  5. "Generality of mis-fit"? The real-life difficulty of matching scales in an interconnected world.

    PubMed

    Keskitalo, E Carina H; Horstkotte, Tim; Kivinen, Sonja; Forbes, Bruce; Käyhkö, Jukka

    2016-10-01

    A clear understanding of processes at multiple scales and levels is of special significance when conceiving strategies for human-environment interactions. However, understanding and application of the scale concept often differ between administrative-political and ecological disciplines. These mirror major differences in potential solutions whether and how scales can, at all, be made congruent. As a result, opportunities of seeking "goodness-of-fit" between different concepts of governance should perhaps be reconsidered in the light of a potential "generality of mis-fit." This article reviews the interdisciplinary considerations inherent in the concept of scale in its ecological, as well as administrative-political, significance and argues that issues of how to manage "mis-fit" should be awarded more emphasis in social-ecological research and management practices. These considerations are exemplified by the case of reindeer husbandry in Fennoscandia. Whilst an indigenous small-scale practice, reindeer husbandry involves multi-level ecological and administrative-political complexities-complexities that we argue may arise in any multi-level system.

  6. Extreme drying event in the Dead Sea basin during MIS5 from the ICDP Dead Sea Deep Drill Core

    NASA Astrophysics Data System (ADS)

    Goldstein, S. L.; Stein, M.; Ben-Avraham, Z.; Agnon, A.; Ariztegui, D.; Brauer, A.; Haug, G. H.; Ito, E.; Kitagawa, H.; Torfstein, A.; Yasuda, Y.; The Icdp-Dsddp Scientific Party

    2011-12-01

    The ICDP funded Dead Sea Deep Drilling Project (DSDDP) recovered the longest and most complete paleo-environmental record in the Middle East, drilling holes of ~450 and ~350 meters in length in deep (~300 m below the lake level) and shallow sites (~3 mbll) respectively. The Dead Sea expands during the glacials and contracts during interglacials, and the sediments comprise a geological archive of the evolving environmental conditions (e.g. rains, floods, dust-storms, droughts). Dead Sea sediments include inorganic aragonite, allowing for dating by U-series (e.g. Haase-Schramm et al. GCA 2004). The deep site cores were opened and described in June 2011. The cores are composed mainly of alternating intervals of marl (aragonite, gypsum and detritus) during glacials, and salts and marls during interglacials. From this stratigraphy we estimate that the deep site core spans ~200 kyr (to the boundary of MIS 6 and 7). A dramatic discovery is a ~40 cm thick interval of partly rounded pebbles at ~235 m below the lake floor. This is the only clean pebbly unit in the entire core. It appears to be a beach layer, near the deepest part of the Dead Sea, lying above ~35 meters of mainly salt. If it is a beach layer, it implies an almost complete dry-down of the paleo-Dead Sea. The pebble layer lies within the last interglacial interval. Our initial attempt to more precisely estimate the age of the possible dry down shows an intriguing correlation between the salt-mud stratigraphy of the Dead Sea core and the oxygen isotope record of Soreq Cave, whereby excursions to light oxygen in the speleothems correspond to periods of salt deposition. Through this comparison, we estimate that the possible dry down occurred during MIS 5e. The occurrence of ~35 meters of mainly salt along with the pebble layer demonstrates a severe dry interval during MIS 5. This observation has implications for the Middle East today, where the Dead Sea level is dropping as all the countries in the area use the

  7. New insights into the paleolake sequence of Baumkirchen (Austria): multiple lake phases and a minor ice advance during MIS 4?

    NASA Astrophysics Data System (ADS)

    Barrett, Samuel; Starnberger, Reinhard; Spötl, Christoph; Brauer, Achim; Tjallingii, Rik; Dulski, Peter; Abfalterer, Christof

    2015-04-01

    The sequence of pre-LGM lacustrine sediments at Baumkirchen (Austria) provides a key record in Alpine Quaternary stratigraphy. These sediments from within the boundary of the Alps potentially provide unique insights into the regional paleoclimate. Recent drilling revealed at least ~250m (the base was not reached) of almost entirely mm- to cm-scale lacustrine sediments. The laminated sediments are comprised of alternations between clayey silt and event layers of medium silt to fine sand. The sequence is interrupted only by a short section of gravel supported in an unlaminated clay-rich matrix. Optically stimulated luminescence dating identifies two distinct sequences: the upper sequence spanning mid-late Marine Isotope Stage (MIS) 3 (~33 to ~45 ka BP), agreeing with existing calibrated radiocarbon ages, and the lower section dating to MIS 4 (~59 to ~73 ka BP). Whether the hiatus is an erosional unconformity, or if the sequences represent two separate lake phases is unclear. Although the precise location of the hiatus is hard to identify, the gravel-rich section lies at the very top of the lower sequence. Pebbles in these gravels are largely angular and contain a significant proportion of non-local, regional lithologies. Such gravels are absent in the remainder of the entire 250 m-thick sequence and hence suggest a unique event rather than e.g. an interfingering local delta gravel foresets with the basin sediments. The gravels are therefore likely to be ice-rafted debris from icebergs from nearby glaciers calving into the lake. This therefore represents the first sedimentological evidence of a MIS 4 ice advance in the Eastern Alps. X-ray fluorescence analysis (ITRAX core scanning) of event layers indicates a strong change in the geochemical composition from generally K, Zr and Ti-rich layers in the upper sequence to mainly Ca and/or Si-rich layers in the lower sequence. X-ray diffraction analysis shows the Ca and Si signals to be controlled by carbonate (both calcite

  8. From Lake Malawi Drilling: East African Climate May Have Caused Major Evolutionary Turnover in Mammalian Species During MIS 14

    NASA Astrophysics Data System (ADS)

    Johnson, Thomas; Werne, Josef

    2016-04-01

    Hominin evolution underwent important changes in the last 1.3 million years, including the extinction of Paranthropus at about 1.2 Ma, leaving Homo as the sole hominin genus. Our genus experienced a major increase in cranial capacity at about 500 ka, and our species, H. sapiens, first appeared at ~200 ka. There was a major turnover in mammalian species in East Africa between 540 and 400 ka, favoring descendants of smaller size and less specialized diet. An understanding of what drove evolution in these directions is fundamental to understanding the development of modern H. sapiens. Climate certainly played a role, for it is the principal factor that influences the distribution of vegetation and habitability on the landscape. We present a 1.3 million year record of temperature and hydroclimate in the basin of Lake Malawi, the second deepest lake in Africa, derived from a 380 m sediment sequence taken from a water depth of 590 m by the Lake Malawi Drilling Project. Seismic reflection profiles used to select the site portray an undisturbed sedimentary section that was not impacted by erosion, turbidity currents or mass wasting events. Sediment samples were analyzed to produce records of temperature (TEX86) and aridity (Ca content and leaf wax δ13C). The temperature record displays progressively larger amplitude glacial-interglacial variations from MIS 13 (~500 ka) to MIS 5 (~125 ka). Intervals of low Ca abundance, which reflect lake high stands, correlate with times of depleted δ13Cwax and relatively warm temperatures. The Malawi basin experienced warm, wet interglacials and cooler (by about 2 - 4°C), dry glacial periods, with roughly a 100 ky periodicity since the Mid-Pleistocene Transition (MPT), about 900 ka. The paleoclimate record from Lake Malawi sediments portrays a transition from a highly variable and predominantly arid climate prior to 900 ka to a progressively more humid environment after the MPT dominated by 100 ky cycles consisting of warm, wet

  9. Post drain-stress behavior of AlGaN/GaN-on-Si MIS-HEMTs

    NASA Astrophysics Data System (ADS)

    Jauss, Simon A.; Kilian, Stefan; Schwaiger, Stephan; Noll, Stefan; Daves, Walter; Ambacher, Oliver

    2016-11-01

    In this paper we investigate the drain stress behavior and charge trapping phenomena of GaN-based high electron mobility transistors (HEMTs). We fabricated GaN-on-Si MIS-HEMTs with different dielectric stacks in the gate and gate-drain access region and performed interface characterization and stress measurements for slow traps analysis. 2-dimensional TCAD simulations were used to compare the electrical field distributions of the devices in OFF-state stress condition. Our results show a high dependency of the on-resistance increase on interfaces in the gate-drain access region. The dielectric interfaces near the channel play a significant role for long term high voltage stress and regeneration of the device.

  10. Late persistence of the Acheulian in southern Britain in an MIS 8 interstadial: evidence from Harnham, Wiltshire

    NASA Astrophysics Data System (ADS)

    Bates, M. R.; Wenban-Smith, F. F.; Bello, S. M.; Bridgland, D. R.; Buck, L. T.; Collins, M. J.; Keen, D. H.; Leary, J.; Parfitt, S. A.; Penkman, K.; Rhodes, E.; Ryssaert, C.; Whittaker, J. E.

    2014-10-01

    This paper presents evidence of the discovery of a new Middle Pleistocene site in central southern England, with undisturbed evidence of hominin occupation well-dated to an interstadial towards the end of Marine Isotope Stage 8, c. 250,000 BP. The site consists of a preserved remnant of a river terrace and its alluvial floodplain overlain by chalk-rich bankside deposits, all abutting a Chalk bedrock riverbank. It preserves an area of occupation with activity focused on the riverbank, complemented by occasional activity on a palaeo-landsurface developed on the surface of the alluvial floodplain. Lithic technology at the site consists almost entirely of handaxe manufacture, allowing attribution to an Acheulian industrial tradition. Mammalian and other palaeo-environmental remains are present and associated with the occupation horizons, including large mammal bones showing signs of hominin interference. Dating was based on OSL determinations on the sediments and amino acid racemisation of molluscan remains, supported by biostratigraphic indications. Besides being a rare instance of an undisturbed Palaeolithic palaeo-landscape covering several hectares, the site contributes to wider Quaternary research concerns over the ability of Middle Pleistocene hominins to tolerate colder climatic episodes in higher latitudes, and over settlement history and changing lithic industrial traditions of northwest Europe in relation to climate change and British peninsularity. It is suggested that the Harnham evidence may represent an insular population that had persisted in southern Britain since MIS 10/9, which became locally extinct during the glacial maximum 8.2 marking the end of MIS 8.

  11. Understanding MIS 11 by integrating land-sea-ice records from the SHACK site (IODP 1385, SW Iberian margin)

    NASA Astrophysics Data System (ADS)

    Oliveira, Dulce; Fernanda Sánchez Goñi, Maria; Naughton, Filipa; Hodell, David; Rodrigues, Teresa; Daniau, Anne-Laure; Eynaud, Frederique; Trigo, Ricardo; Abrantes, Fátima

    2014-05-01

    The understanding of natural climate variability during past interglacials provides crucial information not only of the ongoing climate dynamics, but also of the different processes that triggered glacial inceptions. The relationship (including feedbacks) between insolation, greenhouse gas concentrations (GHG) and ice volume has been invoked to explain the diversity of interglacials (intensity, character and duration), occurring after 800 ka. Superimposed to this orbital-scale variability, climate changes at a millennial time-scale have also punctuated interglacials. Nevertheless, the external (insolation) and internal (ice volume, GHG, ocean and atmospheric dynamics, vegetation) processes controlling the magnitude of the climate optimum (warmest period), length and millennial-scale variability of past warm periods are far from being understood. Consequently, it is of extreme importance to increase the information of natural climate variations that occurred in past interglacial periods. The Marine Isotope Stage (MIS) 11, c. 425-370 ka BP, is, in terms of orbital configuration, one of the closest analogues to the present interglacial and therefore a key past warm period. Here we show the response of SW European ecosystems to climate variability of the North Atlantic region during MIS 11, by comparing directly terrestrial and marine proxies in Site U1385, on the West Iberian margin, from IODP Expedition 339, at a high temporal resolution. Unravelling the processes behind the natural climatic variability of this interglacial at orbital, millennial and sub-millennial scales will improve current knowledge about the evolution of our present warm interval, without human intervention, and on the mechanisms that push Earth's climate into glacial conditions.

  12. Late Pleistocene (MIS5-3) environmental reconstruction from north-eastern Iberia through microvertebrate and palaeobotanical records

    NASA Astrophysics Data System (ADS)

    Allue, Ethel; Bennàssar, Maria; Biltekin, Demet; Blain, Hugues-Alexandre; Burjachs, Francesc; Euba, Itxaso; Expósito, Isabel; Fernández-García, Mónica; López-García, Juan Manuel

    2014-05-01

    The aim of this work is to analyze the environmental changes during the Late Pleistocene on the basis of a multi-approach study based on natural and archaeological deposits from NE Iberian Peninsula. The focussed area, although having a small extension (some 32.000 square kilometres), covers a large range of ecosystems and bioclimatic conditions from the Mediterranean seashore to the summit of the Pyrenean mountain ranges (up to 2000 masl). This synthetical approach includes materials from various contexts including 10 archaeological deposits and a single natural deposit. In this work, plant (pollen and charcoals) and animal (small mammals, amphibians and reptiles) records are being analysed and compared in order to present an overview of the environmental changes occurred from the MIS5 to MIS3. On the first hand, we are using the small-vertebrate records recovered from archaeological deposits. These proxies are mainly the product of pellets from birds of prey and are key ecological markers. On the second hand, palaeobotanical evidences, pollen and charcoal, have different formation processes. Charcoal remains are mostly from archaeological deposits and are due to human activities related to fire showing evidences of the local vegetation. Pollen evidences from archaeological and natural contexts are deposited through natural processes (wind, insects, etc.) and show regional scale vegetation record. Results indicate the presence of temperate elements during all these periods (especially at the seashore area), with a more important representation and extension southwards or changes in altitude from taxa with eurosiberian affinities during coldest periods. Forest coverage, plant and vertebrate distribution along the territory point out a mosaic landscape formed by open areas and forests. These landscapes have probably a more or less Mediterranean or Eurosiberian character depending on the climatic moment and their location with variations along the sequence.

  13. Rapid variability during MIS3 and Termination I from the Western Pacific Warm Pool: new geochemical and sedimentological data

    NASA Astrophysics Data System (ADS)

    Gustiantini, Luli; Bassinot, Franck; Kissel, Catherine; Dang, Haowen; Zuraida, Rina; Zaim, Yadhi

    2015-04-01

    Giant piston core MD10-3339 (39m) was retrieved in the Halmahera basin at ~ 1920m of water depth. It provides a ~50 kyr-long, high-resolution record that makes it possible to decipher the imprint of sea level, deep currents and monsoon/ENSO variability on sedimentation at the south-easternmost entrance of the Indonesian Archipelago, at the heart of the Western Pacific Warm Pool. Our multiproxy study combines (i) stable O and C isotopic analyses and Mg/Ca analyses on planktonic foraminifers, (ii) high-resolution XRF-derived elemental composition, (iii) laser-granulometry and (iv) magnetic anisotropy. The age model is based on mono-foraminifer 14C dates and extrapolated (constant sedimentation rate) before ~ 42 ka. The XRF profiles are dominated by millennial-scale variability, with no evidence of glacial/interglacial changes, suggesting the lack of long-term climate impact or sea-level control on sedimentation at site MD10-3339. A clear G/IG imprint is readily seen, however, on the decarbonated silt record, suggesting a reduction of bottom current activity during the Holocene (finer material) relative to the last glacial (coarser material). This change in current activity is not reflected in the magnetic anisotropy (no change in direction). Elemental profiles associated to terrigeneous inputs (eg. Fe, Ti,..) show a strong co-variance with planktonic δ18O over the 35-45 ka interval and across the last deglaciation. This strong in-phase relationship degrades, however, at the end of MIS3 and during MIS2. We used paired δ18O-Mg/Ca data to infer past changes in local δ18Osw (i.e. advection, local evaporati n/precipitation) and explore the hypothesis that could explain the evolution of δ18O -XRF data relationship through time.

  14. Rolling Malaria Indicator Surveys (rMIS): a potential district-level malaria monitoring and evaluation (M&E) tool for program managers.

    PubMed

    Roca-Feltrer, Arantxa; Lalloo, David G; Phiri, Kamija; Terlouw, Dianne J

    2012-01-01

    Novel malaria monitoring and evaluation (M&E) tools are urgently needed to complement the current "gold standard" Malaria Indicator Surveys (MIS). Rapid up scaling of malaria control efforts is resulting in substantial reductions in malaria burden across sub-Saharan Africa. As transmission goes down, timely, accurate, sub-national, and district level burden estimates are needed to guide increasingly targeted control efforts in remaining hotspot areas. To test a novel district level M&E tool, we have conducted a continuous ("rolling") MIS (rMIS) since May 2010 covering 50 villages in Chikhwawa district in southern Malawi, essentially adapting an existing cross-sectional evaluation tool into a continuous monitoring tool. Here, we report on our experience after completing the first full year of monthly data collection focusing on the methods, operational aspects, and estimated costs of rMIS in a programmatic setting. The potential applicability of this promising M&E approach for district-level program managers and control efforts is discussed.

  15. A History-Coloring Book of the Ojibway Indians, Book No. 3: Original Man & His Grandmother-No-ko-mis. A Mishomis Book.

    ERIC Educational Resources Information Center

    Banai, Edward Benton

    Continuing his tales from the old Ojibway teachings, Mishomis takes up the story of Original Man after he is separated from Wolf. Because he still has many questions, the Creator sends him to find No-ko-mis (Grandmother) who has the wisdom of the spirits. Since she lives far across the water, Original Man has to use his ability and reasoning as a…

  16. Extra-long interglacial in Northern Hemisphere during MISs 15-13 arising from limited extent of Arctic ice sheets in glacial MIS 14.

    PubMed

    Hao, Qingzhen; Wang, Luo; Oldfield, Frank; Guo, Zhengtang

    2015-07-10

    Knowledge of the behavior of Northern Hemisphere (NH) ice sheets over the past million years is crucial for understanding the role of orbitally driven insolation changes on glacial/interglacial cycles. Here, based on the demonstrable link between changes in Chinese loess grain-size and NH ice-sheet extent, we use loess grain-size records to confirm that northern ice-sheets were restricted during marine oxygen isotope stage (MIS) 14. Thus, an unusually long NH interglacial climate of over 100 kyr persisted during MISs 15-13, much longer than expected from marine oxygen isotope records. Taking a global view of the paleoclimate records, MIS 14 inception seems to be a response to changes in Antarctic ice-sheets rather than to NH cooling. Orbital configuration in the two Polar regions shows that the onset of MIS 14 was forced by austral insolation changes, rather than by boreal summer insolation, as Milankovitch theory proposes. Our analysis of MIS 14 raises the possibility that southern insolation forcing may have played an important role in the inception of several other glacials. We suggest that the extra-long NH interglacial climate during MISs 15-13 provided favorable conditions for the second major dispersal episode of African hominins into Eurasia.

  17. Paul Goodman, 30 Years Later: "Growing Up Absurd"; "Compulsory Mis-Education, and The Community of Scholars"; and "The New Reformation"--A Retrospective

    ERIC Educational Resources Information Center

    Kaminsky, James S.

    2006-01-01

    This article is a retrospective account of the legacy of Paul Goodman's major educational works: "Growing Up Absurd"; "Compulsory Mis-education, and The Community of Scholars"; and "The New Reformation." It is argued here that what remains of interest in Goodman's work is to be found in the tropes and the anarchic Zeitgeist of his work. The legacy…

  18. Temperature-Dependent Electrical Properties and Carrier Transport Mechanisms of TMAH-Treated Ni/Au/Al2O3/GaN MIS Diode

    NASA Astrophysics Data System (ADS)

    Reddy, M. Siva Pratap; Puneetha, Peddathimula; Reddy, V. Rajagopal; Lee, Jung-Hee; Jeong, Seong-Hoon; Park, Chinho

    2016-11-01

    The temperature-dependent electrical properties and carrier transport mechanisms of tetramethylammonium hydroxide (TMAH)-treated Ni/Au/Al2O3/GaN metal-insulator-semiconductor (MIS) diodes have been investigated by current-voltage ( I- V) and capacitance-voltage ( C- V) measurements. The experimental results reveal that the barrier height ( I- V) increases whereas the ideality factor decreases with increasing temperature. The TMAH-treated Ni/Au/Al2O3/GaN MIS diode showed nonideal behaviors which indicate the presence of a nonuniform distribution of interface states ( N SS) and effect of series resistance ( R S). The obtained R S and N SS were found to decrease with increasing temperature. Furthermore, it was found that different transport mechanisms dominated in the TMAH-treated Ni/Au/Al2O3/GaN MIS diode. At 150 K to 250 K, Poole-Frenkel emission (PFE) was found to be responsible for the reverse leakage, while Schottky emission (SE) was the dominant mechanism at high electric fields in the temperature range from 300 K to 400 K. Feasible energy band diagrams and possible carrier transport mechanisms for the TMAH-treated Ni/Au/Al2O3/GaN MIS diode are discussed based on PFE and SE.

  19. Abrupt sand-dune accumulation at the northeastern margin of the Tibetan Plateau challenges the wet MIS3a inferred from numerous lake-highstands.

    PubMed

    Long, Hao; Fuchs, Markus; Yang, Linhai; Cheng, Hongyi

    2016-05-13

    Over the Tibetan Plateau and adjacent regions, numerous (14)C-based lake records revealed a ubiquitous wet climatic period during 40-25 ka (late MIS 3), which is in contradiction with the global pattern of generally cold and dry climates. This paper focuses on OSL dating results of a large set of sand dunes and alluvial sediments (50 OSL ages) from the Qinwangchuan (QWC) Basin at the northeast edge of the Tibetan Plateau, with the aim to test the validity of the anomalous wet condition for the late MIS 3 interval, evidenced by numerous lake highstands. The abrupt sand dune accumulation as indication of increased aridity in the study area was OSL dated to ~40-13 ka. This dry climatic inference of the sand dune system from QWC apparently shows no wet MIS 3a event. Thus, the anomalous wet conditions revealed by high lake levels for the late MIS 3 phase may not be a universal phenomena across entire western China.

  20. Extra-long interglacial in Northern Hemisphere during MISs 15-13 arising from limited extent of Arctic ice sheets in glacial MIS 14

    PubMed Central

    Hao, Qingzhen; Wang, Luo; Oldfield, Frank; Guo, Zhengtang

    2015-01-01

    Knowledge of the behavior of Northern Hemisphere (NH) ice sheets over the past million years is crucial for understanding the role of orbitally driven insolation changes on glacial/interglacial cycles. Here, based on the demonstrable link between changes in Chinese loess grain-size and NH ice-sheet extent, we use loess grain-size records to confirm that northern ice-sheets were restricted during marine oxygen isotope stage (MIS) 14. Thus, an unusually long NH interglacial climate of over 100 kyr persisted during MISs 15−13, much longer than expected from marine oxygen isotope records. Taking a global view of the paleoclimate records, MIS 14 inception seems to be a response to changes in Antarctic ice-sheets rather than to NH cooling. Orbital configuration in the two Polar regions shows that the onset of MIS 14 was forced by austral insolation changes, rather than by boreal summer insolation, as Milankovitch theory proposes. Our analysis of MIS 14 raises the possibility that southern insolation forcing may have played an important role in the inception of several other glacials. We suggest that the extra-long NH interglacial climate during MISs 15−13 provided favorable conditions for the second major dispersal episode of African hominins into Eurasia. PMID:26159304

  1. Abrupt sand-dune accumulation at the northeastern margin of the Tibetan Plateau challenges the wet MIS3a inferred from numerous lake-highstands

    PubMed Central

    Long, Hao; Fuchs, Markus; Yang, Linhai; Cheng, Hongyi

    2016-01-01

    Over the Tibetan Plateau and adjacent regions, numerous 14C-based lake records revealed a ubiquitous wet climatic period during 40–25 ka (late MIS 3), which is in contradiction with the global pattern of generally cold and dry climates. This paper focuses on OSL dating results of a large set of sand dunes and alluvial sediments (50 OSL ages) from the Qinwangchuan (QWC) Basin at the northeast edge of the Tibetan Plateau, with the aim to test the validity of the anomalous wet condition for the late MIS 3 interval, evidenced by numerous lake highstands. The abrupt sand dune accumulation as indication of increased aridity in the study area was OSL dated to ~40–13 ka. This dry climatic inference of the sand dune system from QWC apparently shows no wet MIS 3a event. Thus, the anomalous wet conditions revealed by high lake levels for the late MIS 3 phase may not be a universal phenomena across entire western China. PMID:27172907

  2. A Modified Protocol with Improved Detection Rate for Mis-Matched Donor HLA from Low Quantities of DNA in Urine Samples from Kidney Graft Recipients

    PubMed Central

    Kwok, Janette; Choi, Leo C. W.; Ho, Jenny C. Y.; Chan, Gavin S. W.; Mok, Maggie M. Y.; Lam, Man-Fei; Chak, Wai-Leung; Cheuk, Au; Chau, Ka-Foon; Tong, Matthew; Chan, Kwok-Wah; Chan, Tak-Mao

    2016-01-01

    Background Urine from kidney transplant recipient has proven to be a viable source for donor DNA. However, an optimized protocol would be required to determine mis-matched donor HLA specificities in view of the scarcity of DNA obtained in some cases. Methods In this study, fresh early morning urine specimens were obtained from 155 kidney transplant recipients with known donor HLA phenotype. DNA was extracted and typing of HLA-A, B and DRB1 loci by polymerase chain reaction-specific sequence primers was performed using tailor-made condition according to the concentration of extracted DNA. Results HLA typing of DNA extracted from urine revealed both recipient and donor HLA phenotypes, allowing the deduction of the unknown donor HLA and hence the degree of HLA mis-match. By adopting the modified procedures, mis-matched donor HLA phenotypes were successfully deduced in all of 35 tested urine samples at DNA quantities spanning the range of 620–24,000 ng. Conclusions This urine-based method offers a promising and reliable non-invasive means for the identification of mis-matched donor HLA antigens in kidney transplant recipients with unknown donor HLA phenotype or otherwise inadequate donor information. PMID:27861530

  3. Paleosols in low-order streams and valley heads in the Araucaria Plateau - Record of continental environmental conditions in southern Brazil at the end of MIS 3

    NASA Astrophysics Data System (ADS)

    Paisani, Julio Cesar; Pontelli, Marga Eliz; Osterrieth, Margarita Luisa; Paisani, Sani Daniela Lopes; Fachin, Andressa; Guerra, Simone; Oliveira, Leandro

    2014-10-01

    The Araucaria Plateau is a geomorphological unit that occupies approximately three-quarters of the terrain in the southern region of Brazil. The plateau displays different altitudinal levels (600 to <1400 m a.s.l.) that are locally recognized as remnants of planed surfaces (S8-S1). These surfaces are maintained by basic (S3-S8) and acidic (S1 and S2) volcanic flows from the Neocretaceous period of the Paraná Basin. The largest extent of this plateau is located in a humid subtropical climate zone. Colluvial, colluvial-alluvial, alluvial sediments and paleosols (Ab diagnostic horizons) occur predominantly in S2. The paleosols are located in low-hierarchical-order fossil valleys (first- to fourth-order in Strahler's stream classification) and valley heads, which are referred to as paleovalleys in this paper. We employed these paleosols as stratigraphic level markers of the pedogenesis of the regional Upper Quaternary and propose their importance as records of the paleoenvironmental conditions of the Araucaria Plateau in areas above 1200 m a.s.l. These paleosols were dated by 14C and show ages between 23.8 ± 0.05 kyr BP (28.06-29.08 kyr cal. BP) and 41.16 ± 0.48 kyr BP (44.13-45.58 kyr cal. BP). The calibrated ages are related to Marine Isotope Stage 3 (MIS 3), in which the last period of global warming occurred (approximately 60-25 kyr cal. BP). We integrated the morphological, pedogeochemical, clay fraction mineralogy, micromorphological and δC-13 analyses of five paleosols from S2 to verify the paleoenvironmental conditions of the Araucaria Plateau and its correspondence with the paleoclimatic phenomena that were identified on a global scale during MIS 3 in the Southern Hemisphere. We obtained the following conclusions: a) the properties of paleosols reflect pedological processes that are adjusted to the paleoenvironmental conditions at the end of MIS 3 and the transition to MIS 2 (Last Glacial Maximum); b) aplasmogenic partial acidolysis was the predominant

  4. Glacial-interglacial Climate Variability in the Black Sea Region Since MIS 15: Record of Highly Resolved Particle-size Dynamics From the Loess Sequence Mircea Voda, Romania

    NASA Astrophysics Data System (ADS)

    Markley, C.; Machalett, B.; Hambach, U.; Oches, E. A.

    2008-12-01

    The aeolian dust record of the loess sequences in the Dobrogea region, Romania, provides one of the most complete terrestrial climate records in proximity to the Black Sea, enabling us to reconstruct glacial- interglacial climate variability and past atmospheric circulation patterns from marine oxygen-isotope stage (MIS) 15 to the last glacial period (MIS 2) . Presently located at the interface between Mediterranean and continental climates of central and eastern Europe, the loess record of Dobrogea offers insight into long-term paleoenvironmental oscillations triggered by the reciprocity of Mediterranean and continental atmospheric circulation patterns across central and eastern Europe. The 35m thick loess sequence at Mircea Voda shows a well exposed sequence of loess-paleosol couplets that can be traced laterally across a few hundred meters, suggesting a semi-continuous paleoclimate record since MIS 15. In order to assess the loess record of aeolian dynamics and associated past-synoptic atmospheric circulation modes, high resolution particle size analyses have been carried out using a Beckman-Coulter LS 13-320 laser analyzer. With support of amino acid geochronology data, as well as sedimentological features noted in the field, the highly resolved particle-size record of the Mircea Voda loess sequence reveals clear shifts in the aeolian dust record and a general paleoclimatic trend from subtropical (MIS 15) to more continental climates (MIS 1). The observed long trends in the aeolian dust transport record and the general tendency of a progressive aridification since the Middle Pleistocene may be related to interactions and/or shifts of the European polar front and the subtropical jet stream affecting the climate of the Black Sea region on seasonal as well as geological time scales. The data from the Mircea Voda loess profile offer the potential to link continental climate records of SE-Europe with paleoclimate archives of the Black Sea region in order to decipher

  5. Vegetation and climate history in arid western China during MIS2: New insights from pollen and grain-size data of the Balikun Lake, eastern Tien Shan

    NASA Astrophysics Data System (ADS)

    Zhao, Yongtao; An, Cheng-Bang; Mao, Limi; Zhao, Jiaju; Tang, Lingyu; Zhou, Aifeng; Li, Hu; Dong, Weimiao; Duan, Futao; Chen, Fahu

    2015-10-01

    Marine Isotope Stage (MIS) 2 is mostly a cold period encompassing the Last Glacial Maximum (LGM), but the regional expression of MIS2 in arid areas of China is not well known. In this paper, we use high-resolution lacustrine pollen and grain-size records from Balikun Lake to infer vegetation, lake evolution, and climate in arid western China during MIS2. Our results suggest that: 1) the regional vegetation around Balikun was mainly dominated by desert and/or desert-steppe, and Balikun Lake was relatively shallow and experienced high aeolian input during MIS2; 2) distinctive runoff from mountain glacial meltwater in the eastern parts of the Balikun basin caused a high relative abundance of Artemisia pollen during the LGM (26.5-19.2 cal kyr BP), while simultaneously the desert areas expanded as indicated by the high abundance of desert shrubs (e.g., Elaeagnaceae, Rhamnaceae, Hippophae). This cold and dry LGM climate triggered a substantial lowering of lake level; 3) an extremely cold and dry climate prevailing from 17.0 to 15.2 cal kyr BP, correlated with Heinrich event 1 (H1), would explain the low vegetation cover found then; and 4) the warm and humid Bølling/Allerød interstadial (BA: ca. 15-ca. 13 cal kyr BP) is clearly recorded in the Balikun region by the development of wetland herb communities (e.g., Poaceae, Cyperaceae, Typha), and the lake level rose due to increased runoff. Our results challenge the traditional view of cold and wet climatic conditions and high lake levels in arid western China during the LGM, and we propose that changes in local temperature modulated by July insolation was an indispensable factor in triggering vegetation evolution in the Balikun region during MIS2.

  6. Efficient III-Nitride MIS-HEMT devices with high-κ gate dielectric for high-power switching boost converter circuits

    NASA Astrophysics Data System (ADS)

    Mohanbabu, A.; Mohankumar, N.; Godwin Raj, D.; Sarkar, Partha; Saha, Samar K.

    2017-03-01

    The paper reports the results of a systematic theoretical study on efficient recessed-gate, double-heterostructure, and normally-OFF metal-insulator-semiconductor high-electron mobility transistors (MIS-HEMTs), HfAlOx/AlGaN on Al2O3 substrate. In device architecture, a thin AlGaN layer is used in the AlGaN graded barrier MIS-HEMTs that offers an excellent enhancement-mode device operation with threshold voltage higher than 5.3 V and drain current above 0.64 A/mm along with high on-current/off-current ratio over 107 and subthreshold slope less than 73 mV/dec. In addition, a high OFF-state breakdown voltage of 1200 V is achieved for a device with a gate-to-drain distance and field-plate length of 15 μm and 5.3 μm, respectively at a drain current of 1 mA/mm with a zero gate bias, and the substrate grounded. The numerical device simulation results show that in comparison to a conventional AlGaN/GaN MIS-HEMT of similar design, a graded barrier MIS-HEMT device exhibits a better interface property, remarkable suppression of leakage current, and a significant improvement of breakdown voltage for HfAlOx gate dielectric. Finally, the benefit of HfAlOx graded-barrier AlGaN MIS-HEMTs based switching devices is evaluated on an ultra-low-loss converter circuit.

  7. Development of a high-resolution record of Great Basin climate change during MIS 5, 6, and 7

    NASA Astrophysics Data System (ADS)

    Cross, M.; McGee, D.; Broecker, W. S.; Quade, J.; Cheng, H.; Edwards, R.

    2013-12-01

    As evinced by the cycles of the large paleolakes Lahontan and Bonneville, the currently semi-arid to arid Great Basin region of the United States has experienced significant changes in climate and water balance in the past. Although there has been substantial research concerning these changes for times around and since the last glacial maximum, relatively little is known about the region's previous climate and water balance history. There is a clear need for a long-term record for earlier glacial and interglacial periods. Here, we present some of our initial results from Lehman Cave (39.01°N, 114.22°W), a well-decorated, active cave located on the edge of the Bonneville Basin in the Great Basin National Park, for times correlating with large portions of Marine Oxygen Isotope Stages (MIS) 5, 6, and 7. We initially surveyed a suite of speleothems to obtain times and durations of growth phases to aid in choosing samples appropriate for more extensive analysis. Approximately eighty 2 to 10 mg samples with a mean 238U of 400 ppb, representing most of the major growth phases of this suite of 20 speleothems, were analyzed for preliminary uranium-thorium dates. A subset of eight of these stalagmites grew collectively over large portions of MIS 5 and 6 (an interval that includes the Little Valley lake cycle of the Bonneville Basin) as well as a substantial portion of MIS 7. This record includes several significant periods of contemporaneous growth, including: 81.5 to 103 ka, which corresponds to the interval between Dansgaard-Oeschger events 21 and 23; 204 to 207 ka; and 118 to 132 ka, an interval including the beginning of the last interglacial period and the end of Termination II and Heinrich Stadial 11. We have yet to identify growth phases between 103 to 118 ka, 134 to 137 ka, and 164 to 169 ka. Initial stable isotope results indicate a shift of approximately +3‰ δ18O and +5‰ δ13C around 131 × 2.5 ka, which agrees within error with the findings of Shakun et al

  8. An interdisciplinary approach to reconstructing hydrologically controlled terrestrial habitat dynamics during MIS 5 from sediments of Lake Ohrid (Albania, Macedonia)

    NASA Astrophysics Data System (ADS)

    Holtvoeth, Jens; Vogel, Hendrik; Rushworth, Danielle; Copsey, Harriet; Imeri, Alma; Valsecchi, Verushka; Cara, Magdalena; Schouten, Stefan; Wagner, Bernd; Wolff, George A.; Pancost, Richard D.

    2016-04-01

    We investigated sediments from a piston core (site Co1202) in the northeastern part of Lake Ohrid (Macedonia, Albania) that cover the period from 136 to 97 ka, i.e. most of marine isotope stage (MIS) 5 including Termination II and the peak warm period of MIS 5e (Eemian). The aim of the study was to reconstruct climatically controlled changes in the terrestrial habitat by combining data from elemental, lipid biomarker (alkyl lipids, glycerol dialkyl glycerol tetraethers/GDGTs) and compound-specific carbon isotope analyses with pollen data. Comparison of biomarker data from sediments and modern materials shows a close similarity between the average biomarker composition of sediments and soils. This is confirmed by statistical analyses, implying that a dominant proportion of the sedimentary alkyl lipids derives from soils while aquatic sources (macrophytes, phytoplankton) can be ruled out as a major source. The carbonate record of the Co1202 sediments and the GDGT-based proxy for lake surface water temperature (TEX86) closely follow climatic trends as they are known from the North Atlantic realm, including marine isotope sub-stage 5d and short-term climate events such as cold events C25, C24 and C23. By contrast, proxies based on alkyl lipid composition reveal an entirely different pattern. Episodes of slow, continuous change are disrupted by abrupt shifts. This suggests a threshold-controlled system, with supply of organic matter from specific sources being increased or suppressed by a sudden change of supply pathways. Such a mechanism is provided by lake level change that includes rapid flooding or exposure of extensive tectonic terraces in the vicinity of site Co1202 as documented by geophysical surveys. Both flooding and exposure change the areas that certain habitats occupy in the catchment of the site, e.g., the proportions of vegetation and soils on the surrounding mountain slopes relative to that on low-lying terrace surfaces. Several such abrupt changes can

  9. Coral Reef Response to Marine Isotope Stage (MIS) 5e Sea Level Changes in the Granitic Seychelles

    NASA Astrophysics Data System (ADS)

    Vyverberg, K.; Dechnik, B.; Dutton, A.; Webster, J.; Zwartz, D.

    2015-12-01

    Sea-level position has a direct control on coral reef morphology and composition. Examining changes in these parameters in fossil reefs can inform reconstructions of past sea-level behavior and, indirectly, ice sheet dynamics. Here we provide a detailed examination of fossil reefs from Marine Isotope Stage (MIS) 5e. These fossil reefs are located in the granitic Seychelles, which is tectonically stable site and far-field from the former margins of Northern Hemisphere ice sheets. To reconstruct relative sea level (RSL), we combine RTK and Total Station elevation surveys with sedimentary and taxonomic evaluations of eight fossil reef sites. Carbonate coralgal reef buildups of the shallowest portion of the reef are preserved in limestone outcrops that are protected by granite boulder overhangs. Two primary outcrop morphologies were observed at these sites: plastering and massive. Plastering outcrops manifest as thin (~ 1 m height x 1 m width x 0.5 m depth) vertical successions of reef framework and detritus, while massive outcrops are larger (~ 2-6 m height x 2-6 m width x 1-2 m depth). The base of these limestone outcrops consistently record a period of reef growth, characterized by corals or coralline algae colonizing the surface or face of a granite boulder and building upwards. This lower reefal unit is capped by a disconformity that is commonly overlain by coral rubble or a ~10 cm thick layer of micrite. Rubble units contain coarse fragments of the coralgal reef buildups while micrite layers consist of a relatively homogeneous fine-grained carbonate, bearing coral-dwelling, Pyrgomatid barnacles. In many of the outcrops, this succession is repeated upsection with another unit of coralgal reef framework capped by a disconformity that is recognized by the sharp transition to coral rubble or micrite with barnacles. We identified four distinct fossil coralgal assemblages in the limestone outcrops. These assemblages are consistent with modern assemblages which

  10. DC characteristics of ALD-grown Al2O3/AlGaN/GaN MIS-HEMTs and HEMTs at 600 °C in air

    NASA Astrophysics Data System (ADS)

    Suria, Ateeq J.; Saran Yalamarthy, Ananth; So, Hongyun; Senesky, Debbie G.

    2016-11-01

    To the best of our knowledge, the 600 °C device characteristics detailed here reflect the highest operation temperature reported for AlGaN/GaN metal-insulator-semiconductor high electron mobility transistors (MIS-HEMTs) in air which supports the realization of electronics for high-temperature applications (e.g., space exploration, combustion and downhole). The high-temperature response of Al2O3/AlGaN/GaN MIS-HEMTs with Al2O3 deposited by plasma-enhanced atomic layer deposition (ALD) as the gate dielectric and passivation layers was examined here. More specifically, the DC current-voltage response and the threshold voltage characteristics of the MIS-HEMTs were evaluated to temperatures up to 600 °C in air. For comparison, the response of AlGaN/GaN HEMTs without the ALD Al2O3 layer was also measured. It was observed that the HEMTs failed above 300 °C accompanied by a ˜500 times increase in leakage current and observation of bubbles formed in active region of gate. On the contrary, the MIS-HEMTs continued to operate normally up to 600 °C. However, within the 30 min period exposed to 600 °C the MIS-HEMT degraded permanently. This was observed at 20 °C after return from operation at 600 °C as a change in threshold voltage and saturation drain current. The failure of the HEMTs is suggested to be due to the diffusion of gate metals (Ni and Au) into the active regions of the AlGaN/GaN heterostructure, which creates additional leakage current pathways. The impact of strain relaxation and interfacial trapped charges on threshold voltage as a function of temperature was studied using an energy band-gap model. The ALD Al2O3 gate dielectric layer acts as a diffusion barrier to the Ni and Au gate metals, thus enabling short-term operation of MIS-HEMTs to 600 °C, the highest operation temperature reported for this device architecture to date.

  11. A mixed solution-processed gate dielectric for zinc-tin oxide thin-film transistor and its MIS capacitance

    NASA Astrophysics Data System (ADS)

    Kim, Hunho; Kwack, Young-Jin; Yun, Eui-Jung; Choi, Woon-Seop

    2016-09-01

    Solution-processed gate dielectrics were fabricated with the combined ZrO2 and Al2O3 (ZAO) in the form of mixed and stacked types for oxide thin film transistors (TFTs). ZAO thin films prepared with double coatings for solid gate dielectrics were characterized by analytical tools. For the first time, the capacitance of the oxide semiconductor was extracted from the capacitance-voltage properties of the zinc-tin oxide (ZTO) TFTs with the combined ZAO dielectrics by using the proposed metal-insulator-semiconductor (MIS) structure model. The capacitance evolution of the semiconductor from the TFT model structure described well the threshold voltage shift observed in the ZTO TFT with the ZAO (1:2) gate dielectric. The electrical properties of the ZTO TFT with a ZAO (1:2) gate dielectric showed low voltage driving with a field effect mobility of 37.01 cm2/Vs, a threshold voltage of 2.00 V, an on-to-off current ratio of 1.46 × 105, and a subthreshold slope of 0.10 V/dec.

  12. Environmental changes of the Mazovian (Holsteinian /~MIS 11) palaeolake near Szymanowo (eastern Poland) in the light of malacological analysis

    NASA Astrophysics Data System (ADS)

    Szymanek, Marcin

    2014-06-01

    The malacofauna of the palaeolake deposits at Szymanowo (eastern Poland) was investigated. It represents the younger part of the climatic optimum of the Mazovian (Holsteinian) Interglacial (~MIS 11) and possibly the postoptimal period. The mollusc assemblage is composed of both standing and running water species, mostly connected with temperate climate. The presence of biostratigraphical indicators of the Mazovian, Viviparus diluvianus (Kunth, 1865), Lithoglyphus jahni Urbański, 1975 and Pisidium clessini Neumayr, 1875, is noteworthy. Variability in the structure and composition of the assemblage enables palaeoecological reconstruction. Changes in the water-level, vegetation and energy conditions are inferred from the malacological succession. Three stages of the lake development were distinguished. The first one is connected with deeper conditions and predominance of V. diluvianus and L. jahni. The second one, dominated by Bithynia tentaculata (Linnaeus, 1758), records a fall of the water-level and the growth of aquatic plants, evidenced by high frequencies of Valvata cristata Muller, 1774 and Acroloxus lacustris (Linnaeus, 1758). The third stage corresponds to another rise of the water-level and an increase in V. diluvianus, L. jahni, Valvata piscinalis Muller, 1774 and Pisidium henslowanum (Sheppard, 1823), which evidence some higher energy conditions.

  13. Aligning MIS5 proxy records from Lake Ohrid (FYROM) with independently dated Mediterranean archives: implications for core chronology

    NASA Astrophysics Data System (ADS)

    Zanchetta, G.; Regattieri, E.; Giaccio, B.; Wagner, B.; Sulpizio, R.; Francke, A.; Vogel, L. H.; Sadori, L.; Masi, A.; Sinopoli, G.; Lacey, J. H.; Leng, M. L.; Leicher, N.

    2015-10-01

    The DEEP site sediment sequence obtained during the ICDP SCOPSCO project at Lake Ohrid was dated using tephrostratigraphic information, cyclostratigraphy, and orbital tuning through marine isotope record. Although this approach is suitable for the generation of a general chronological framework of the long succession, it is insufficient to resolve more detailed paleoclimatological questions, such as leads and lags of climate events between marine and terrestrial records or between different regions. In this paper, we demonstrate how the use of different tie points can affect cyclostratigraphy and orbital tuning for the period between ca. 140 and 70 ka and how the results can be correlated with directly/indirectly radiometrically-dated Mediterranean marine and continental proxy records. The alternative age model obtained shows consistent differences with that proposed by Francke et al. (2015) for the same interval, in particular at the level of the MIS6-5e transition. According to this age model, different proxies from the DEEP site sediment record support an increase of temperatures between glacial to interglacial conditions, which is almost synchronous with a rapid increase in sea surface temperature observed in the western Mediterranean. The results show how important a detailed study of independent chronological tie points is for synchronizing different records and to highlight asynchronisms of climate events.

  14. Oceanic response to topography and orbital forcing during the MIS31: The reversal effect of both forcing

    NASA Astrophysics Data System (ADS)

    Justino, F. J.; Lindemann, D.; Kucharski, F.; Wilson, A.; Stordal, F.; Bromwich, D. H.

    2015-12-01

    Earth climate has been punctuated by cold (glacial) and warm (interglacial) intervals associated with modification of the planetary orbit and subsequently changes in paleotopography. This presentation will focuses on the MIS31 interglacial and the oceanic response to WAIS topography and Orbital forcing. A coupled model, referred to as ICTP-CGCM, is applied to disentangle individual air-sea exchange processes driven by those forcings. The ICTP-CGCM is an useful tool to evaluate large-scale mechanism associated with interhemispheric coupling and full ocean dynamics, including for instance, a better representation of atmospheric and oceanic heat transport Initial results demonstrated that the orbital and topography forcing acting in distinct manner. Where the topography forcing leads to cool (warm) the Northern (Southern) Hemisphere the orbital forcing delivers reversed response. As compared to the present day climate, the introduction of both forcings in the ICTP-CGCM model results in weaker rate of the North Atlantic Deep Water formation and subequently reduced Atlantic northward oceanic heat transport. It should be noted that the anomalous pattern of SST as simulated by the topography forcing simulation resembles many aspects of the interhemispheric seesaw mechanisms. This study is supported by FAPEMIG Grant 551-13 and CNPq 407681.

  15. A mixed solution-processed gate dielectric for zinc-tin oxide thin-film transistor and its MIS capacitance

    PubMed Central

    Kim, Hunho; Kwack, Young-Jin; Yun, Eui-Jung; Choi, Woon-Seop

    2016-01-01

    Solution-processed gate dielectrics were fabricated with the combined ZrO2 and Al2O3 (ZAO) in the form of mixed and stacked types for oxide thin film transistors (TFTs). ZAO thin films prepared with double coatings for solid gate dielectrics were characterized by analytical tools. For the first time, the capacitance of the oxide semiconductor was extracted from the capacitance-voltage properties of the zinc-tin oxide (ZTO) TFTs with the combined ZAO dielectrics by using the proposed metal-insulator-semiconductor (MIS) structure model. The capacitance evolution of the semiconductor from the TFT model structure described well the threshold voltage shift observed in the ZTO TFT with the ZAO (1:2) gate dielectric. The electrical properties of the ZTO TFT with a ZAO (1:2) gate dielectric showed low voltage driving with a field effect mobility of 37.01 cm2/Vs, a threshold voltage of 2.00 V, an on-to-off current ratio of 1.46 × 105, and a subthreshold slope of 0.10 V/dec. PMID:27641430

  16. Subsurface North Atlantic warming as a trigger of rapid cooling events: evidences from the Early Pleistocene (MIS 31-19)

    NASA Astrophysics Data System (ADS)

    Hernández-Almeida, I.; Sierro, F.-J.; Cacho, I.; Flores, J.-A.

    2014-10-01

    Subsurface water column dynamics in the subpolar North Atlantic were reconstructed in order to improve the understanding of the cause of abrupt IRD events during cold periods of the Early Pleistocene. We used Mg / Ca-based temperatures of deep-dwelling (Neogloboquadrina pachyderma sinistral) planktonic foraminifera and paired Mg / Ca-δ18O measurements to estimate the subsurface temperatures and δ18O of seawater at Site U1314. Carbon isotopes on benthic and planktonic foraminifera from the same site provide information about the ventilation and water column nutrient gradient. Mg / Ca-based temperatures and δ18O of seawater suggest increased temperatures and salinities during ice-rafting, likely due to enhanced northward subsurface transport of subtropical waters during periods of AMOC reduction. Planktonic carbon isotopes support this suggestion, showing coincident increased subsurface ventilation during deposition of ice-rafted detritus (IRD). Warm waters accumulated at subsurface would result in basal warming and break-up of ice-shelves, leading to massive iceberg discharges in the North Atlantic. Release of heat and salt stored at subsurface would help to restart the AMOC. This mechanism is in agreement with modelling and proxy studies that observe a subsurface warming in the North Atlantic in response to AMOC slowdown during the MIS3.

  17. Subsurface North Atlantic warming as a trigger of rapid cooling events: evidence from the early Pleistocene (MIS 31-19)

    NASA Astrophysics Data System (ADS)

    Hernández-Almeida, I.; Sierro, F.-J.; Cacho, I.; Flores, J.-A.

    2015-04-01

    Subsurface water column dynamics in the subpolar North Atlantic were reconstructed in order to improve the understanding of the cause of abrupt ice-rafted detritus (IRD) events during cold periods of the early Pleistocene. We used paired Mg / Ca and δ18O measurements of Neogloboquadrina pachyderma (sinistral - sin.), deep-dwelling planktonic foraminifera, to estimate the subsurface temperatures and seawater δ18O from a sediment core from Gardar Drift, in the subpolar North Atlantic. Carbon isotopes of benthic and planktonic foraminifera from the same site provide information about the ventilation and water column nutrient gradient. Mg / Ca-based temperatures and seawater δ18O suggest increased subsurface temperatures and salinities during ice-rafting, likely due to northward subsurface transport of subtropical waters during periods of weaker Atlantic Meridional Overturning Circulation (AMOC). Planktonic carbon isotopes support this suggestion, showing coincident increased subsurface ventilation during deposition of IRD. Subsurface accumulation of warm waters would have resulted in basal warming and break-up of ice-shelves, leading to massive iceberg discharges in the North Atlantic. The release of heat stored at the subsurface to the atmosphere would have helped to restart the AMOC. This mechanism is in agreement with modelling and proxy studies that observe a subsurface warming in the North Atlantic in response to AMOC slowdown during Marine Isotope Stage (MIS) 3.

  18. Multiproxy record of the last interglacial (MIS 5e) off central and northern California, U.S.A., from Ocean Drilling Program sites 1018 and 1020

    USGS Publications Warehouse

    Poore, Richard Z.; Dowsett, H.J.; Barron, J.A.; Heusser, L.; Ravelo, A.C.; Mix, A.

    2000-01-01

    Environmental and climatic conditions during the last interglacial (about 125,000 years ago) along the Central and Northern California coastal region are interpreted from study of marine cores recovered by the Ocean Drilling Program at sites 1018 and 1020. Marine microfossil and pollen assemblages, oxygen isotopes in benthic foraminifers, physical properties, and calcium carbonate contents of cored sediments are proxies indicating strong links between the marine and terrestrial environments during marine isotope stage 5 (MIS 5). At the beginning of the last interglacial (MIS 5e), reduction in global ice volume, increase in surface temperature, and warming of air temperature along the Central and Northern California coast were synchronous within the resolution of our sampling record.

  19. Techno-Cultural Characterization of the MIS 5 (c. 105 - 90 Ka) Lithic Industries at Blombos Cave, Southern Cape, South Africa.

    PubMed

    Douze, Katja; Wurz, Sarah; Henshilwood, Christopher Stuart

    2015-01-01

    Blombos Cave is well known as an important site for understanding the evolution of symbolically mediated behaviours among Homo sapiens during the Middle Stone Age, and during the Still Bay in particular. The lower part of the archaeological sequence (M3 phase) contains 12 layers dating to MIS 5 with ages ranging from 105 to 90 ka ago (MIS 5c to 5b) that provide new perspectives on the technological behaviour of these early humans. The new data obtained from our extensive technological analysis of the lithic material enriches our currently limited knowledge of this time period in the Cape region. By comparing our results with previously described lithic assemblages from sites south of the Orange River, we draw new insights on the extent of the techno-cultural ties between these sites and the M3 phase at Blombos Cave and highlight the importance of this phase within the Middle Stone Age cultural stratigraphy.

  20. The comprehensive study and the reduction of contact resistivity on the n-InGaAs M-I-S contact system with different inserted insulators

    SciTech Connect

    Liao, M.-H. Lien, C.

    2015-05-15

    Five different kinds of insulators including BaTiO{sub 3}, TiO{sub 2}, Al{sub 2}O{sub 3}, CdO and ZnO on the n-type InGaAs metal-insulator-semiconductor (M-I-S) ohmic contact structure are studied. The effect for the dielectric constant (ε) of inserted insulator and the conduction band offset (CBO) between an insulator and semiconductor substrate is analyzed by a unified M-I-S contact model. Based on the theoretical model and experimental data, we demonstrates that the inserted ZnO insulator with the high electron affinity and the low CBO (∼0.1 eV) to the InGaAs substrate results in ∼10 times contact resistivity reduction, even the ε of ZnO is not pretty high (∼10)

  1. Techno-Cultural Characterization of the MIS 5 (c. 105 – 90 Ka) Lithic Industries at Blombos Cave, Southern Cape, South Africa

    PubMed Central

    Douze, Katja; Wurz, Sarah; Henshilwood, Christopher Stuart

    2015-01-01

    Blombos Cave is well known as an important site for understanding the evolution of symbolically mediated behaviours among Homo sapiens during the Middle Stone Age, and during the Still Bay in particular. The lower part of the archaeological sequence (M3 phase) contains 12 layers dating to MIS 5 with ages ranging from 105 to 90 ka ago (MIS 5c to 5b) that provide new perspectives on the technological behaviour of these early humans. The new data obtained from our extensive technological analysis of the lithic material enriches our currently limited knowledge of this time period in the Cape region. By comparing our results with previously described lithic assemblages from sites south of the Orange River, we draw new insights on the extent of the techno-cultural ties between these sites and the M3 phase at Blombos Cave and highlight the importance of this phase within the Middle Stone Age cultural stratigraphy. PMID:26580219

  2. A high-elevation, multi-proxy biotic and environmental record of MIS 6-4 from the Ziegler Reservoir fossil site, Snowmass Village, Colorado, USA

    USGS Publications Warehouse

    Miller, Ian M.; Pigati, Jeffrey S.; Anderson, R. Scott; Johnson, Kirk R.; Mahan, Shannon; Ager, Thomas A.; Baker, Richard G.; Blaauw, Maarten; Bright, Jordon; Brown, Peter M.; Bryant, Bruce; Calamari, Zachary T.; Carrara, Paul E.; Michael D., Cherney; Demboski, John R.; Elias, Scott A.; Fisher, Daniel C.; Gray, Harrison J.; Haskett, Danielle R.; Honke, Jeffrey S.; Jackson, Stephen T.; Jiménez-Moreno, Gonzalo; Kline, Douglas; Leonard, Eric M.; Lifton, Nathaniel A.; Lucking, Carol; McDonald, H. Gregory; Miller, Dane M.; Muhs, Daniel R.; Nash, Stephen E.; Newton, Cody; Paces, James B.; Petrie, Lesley; Plummer, Mitchell A.; Porinchu, David F.; Rountrey, Adam N.; Scott, Eric; Sertich, Joseph J. W.; Sharpe, Saxon E.; Skipp, Gary L.; Strickland, Laura E.; Stucky, Richard K.; Thompson, Robert S.; Wilson, Jim

    2014-01-01

    In North America, terrestrial records of biodiversity and climate change that span Marine Oxygen Isotope Stage (MIS) 5 are rare. Where found, they provide insight into how the coupling of the ocean–atmosphere system is manifested in biotic and environmental records and how the biosphere responds to climate change. In 2010–2011, construction at Ziegler Reservoir near Snowmass Village, Colorado (USA) revealed a nearly continuous, lacustrine/wetland sedimentary sequence that preserved evidence of past plant communities between ~ 140 and 55 ka, including all of MIS 5. At an elevation of 2705 m, the Ziegler Reservoir fossil site also contained thousands of well-preserved bones of late Pleistocene megafauna, including mastodons, mammoths, ground sloths, horses, camels, deer, bison, black bear, coyotes, and bighorn sheep. In addition, the site contained more than 26,000 bones from at least 30 species of small animals including salamanders, otters, muskrats, minks, rabbits, beavers, frogs, lizards, snakes, fish, and birds. The combination of macro- and micro-vertebrates, invertebrates, terrestrial and aquatic plant macrofossils, a detailed pollen record, and a robust, directly dated stratigraphic framework shows that high-elevation ecosystems in the Rocky Mountains of Colorado are climatically sensitive and varied dramatically throughout MIS 5.

  3. Latest Quaternary Paleoceanography of the Oga peninsula, Japan Sea side of Japan: glaciatin in MIS 12 as evidenced by lithostratigraphy and nannofossil biostratigraphy

    NASA Astrophysics Data System (ADS)

    Sato, T.; Watanabe, M.; Kita, I.; Imai, R.

    2012-12-01

    The uppermost Quaternary Wakimoto Formation, distributed in the northern part of Oga Peninsula, is composed of sandy siltstone, siltstone and alternation of very fine sandstone and sandy siltstone. The formation is divided into seven lithostratigraphic Units. The upper part of the formation is divided into seven lithostratigraphic units. Unit 1, situated in the lowest part of the studied section, is composed of poorly laminated sandy siltstone. The unit is also characterized by presence of isolated granule to pebble gravels which are interpreted as IRD (ice rafted debris). Lithology of units 4 to 6, the upper part of section, is changed to siltstone, and unit 7, the uppermost unit of the section, is characterized by sandy siltstone to siltstone with carbonaceous matters. The shibikawa Formation, conformably overlies the Wakimoto Formation, is composed of hummocky stratified sandstone and lignite bed. These lithostratigraphic changes indicates that the sedimentary environment was changed from upper bathyal to neritic or brackish environment. The Pumice tuff layer (B-Og) situated in the lower part of Shibikawa Formation, is correlated to Top of MIS 12. Calcareus nannofossil study also indicates that the unit 5 in the upper part of the Wakimoto Formation is traceable to just below the peak of MIS 12 based on the top datum of Pseudoemiliania lacunosa. From these facts that the studied section is correlated to the upper part of MIS 12, and the area was influenced by iceberg around 450ka as evidenced by presence of IRD.;

  4. Assessment of the reliability and consistency of the "malnutrition inflammation score" (MIS) in Mexican adults with chronic kidney disease for diagnosis of protein-energy wasting syndrome (PEW).

    PubMed

    González-Ortiz, Ailema Janeth; Arce-Santander, Celene Viridiana; Vega-Vega, Olynka; Correa-Rotter, Ricardo; Espinosa-Cuevas, María de Los Angeles

    2014-10-04

    Antecedentes: El síndrome de desgaste proteínico-energético (DPE) se refiere a una condición de desnutrición, inflamación, anorexia, y emaciación de reservas corporales resultante de las condiciones inflamatorias y no inflamatorias que prevalecen en pacientes con enfermedad renal crónica (ERC).Una forma ampliamente descrita en la literatura para evaluar el DPE es el Malnutrition Inflamation Score (MIS). Objetivo: Valorar la fiabilidad y consistencia del MIS en adultos mexicanos con ERC en Hemodiálisis (HD) para Diagnóstico de DPE. Métodos: Estudio de pruebas diagnósticas. Se analizó una muestra de 45 adultos con ERC en HD, Durante el periodo Junio-Julio 2014. El instrumento se aplicó en 2 ocasiones, la fiabilidad test-retest se calculó mediante el Coeficiente de correlación Intraclase (CCI), la consistencia interna del cuestionario se analizó mediante el Coeficiente de Cronbach. Se calculó una prueba de Kappa ponderada para estimar la validez del instrumento, posteriormente se comparó con el índice nutricional de Bilbrey (IB). Resultados: La fiabilidad entre cuestionarios valorada en la muestra de pacientes fue de CCI = 0.829. La concordancia entre observaciones MIS es considerada como adecuada = 0.585 (p.

  5. A high-elevation, multi-proxy biotic and environmental record of MIS 6–4 from the Ziegler Reservoir fossil site, Snowmass Village, Colorado, USA

    SciTech Connect

    Ian M. Miller; Mitchell A. Plummer; Various Others

    2014-10-01

    In North America, terrestrial records of biodiversity and climate change that span Marine Oxygen Isotope Stage (MIS) 5 are rare. Where found, they provide insight into how the coupling of the ocean–atmosphere system is manifested in biotic and environmental records and how the biosphere responds to climate change. In 2010–2011, construction at Ziegler Reservoir near Snowmass Village, Colorado (USA) revealed a nearly continuous, lacustrine/wetland sedimentary sequence that preserved evidence of past plant communities between ~140 and 55 ka, including all of MIS 5. At an elevation of 2705 m, the Ziegler Reservoir fossil site also contained thousands of well-preserved bones of late Pleistocene megafauna, including mastodons, mammoths, ground sloths, horses, camels, deer, bison, black bear, coyotes, and bighorn sheep. In addition, the site contained more than 26,000 bones from at least 30 species of small animals including salamanders, otters, muskrats, minks, rabbits, beavers, frogs, lizards, snakes, fish, and birds. The combination of macro- and micro-vertebrates, invertebrates, terrestrial and aquatic plant macrofossils, a detailed pollen record, and a robust, directly dated stratigraphic framework shows that high-elevation ecosystems in the Rocky Mountains of Colorado are climatically sensitive and varied dramatically throughout MIS 5

  6. Comparative study on nitridation and oxidation plasma interface treatment for AlGaN/GaN MIS-HEMTs with AlN gate dielectric

    NASA Astrophysics Data System (ADS)

    Zhu, Jie-Jie; Ma, Xiao-Hua; Hou, Bin; Chen, Li-Xiang; Zhu, Qing; Hao, Yue

    2017-02-01

    This paper demonstrated the comparative study on interface engineering of AlN/AlGaN/GaN metal–insulator–semiconductor high-electron-mobility transistors (MIS-HEMTs) by using plasma interface pre-treatment in various ambient gases. The 15 nm AlN gate dielectric grown by plasma-enhanced atomic layer deposition significantly suppressed the gate leakage current by about two orders of magnitude and increased the peak field-effect mobility by more than 50%. NH3/N2 nitridation plasma treatment (NPT) was used to remove the 3 nm poor-quality interfacial oxide layer and N2O/N2 oxidation plasma treatment (OPT) to improve the quality of interfacial layer, both resulting in improved dielectric/barrier interface quality, positive threshold voltage (V th) shift larger than 0.9 V, and negligible dispersion. In comparison, however, NPT led to further decrease in interface charges by 3.38 × 1012 cm‑2 and an extra positive V th shift of 1.3 V. Analysis with fat field-effect transistors showed that NPT resulted in better sub-threshold characteristics and transconductance linearity for MIS-HEMTs compared with OPT. The comparative study suggested that direct removing the poor interfacial oxide layer by nitridation plasma was superior to improving the quality of interfacial layer by oxidation plasma for the interface engineering of GaN-based MIS-HEMTs.

  7. Variations of Minor elements during MIS3a in the glacial tills at Mt.Yulong, South-eastern Tibetan plateau

    NASA Astrophysics Data System (ADS)

    He, Yuanqing; He, Ze

    2016-04-01

    Several profiles of glacial varve sediments in Mt.Yulong (27°7'43"N, 100°14'53"E) were found and sampled recently, where is the lowest latitude alpine glacier-covered area in the region of south-eastern Tibetan Plateau influenced by South Asian monsoon. High resolution X-ray fluorescence (mXRF) was firstly applied to observe and describe these sediments in details, and the varve sediments are dated between 31620±180 and 38230±380BP determined by 14C dating,corresponding to Marine Isotope Stage 3a(MIS3a). Minor elements in the glacial till can be related to precipitation amount because this kind of accumulation is strongly affected by monsoon rainfall in the region. 4 general circle variations have been identified in the varve sediments. The changes of analyzed lithogenic elements(Ga, Si, Fe,Sr,Zr )in the sediments show distinct centennial to millennial variable features during MIS3a. Principal components analysis of our geochemical dataset suggests a close link between high Rb/Sr ratio, Mn/Fe ratio and Zr abundance in the deposition that could be dealing with both chemical weathering process and hydrological process. Key Words: Minor elements, MIS 3a, Glacial till, Mt.Yulong, South-eastern Tibetan plateau;

  8. A Single Base Pair Mutation Encoding a Premature Stop Codon in the MIS type II receptor is Responsible for Canine Persistent Müllerian Duct Syndrome

    PubMed Central

    Wu, Xiufeng; Wan, Shengqin; Pujar, Shashikant; Haskins, Mark E.; Schlafer, Donald H.; Lee, Mary M.; Meyers-Wallen, Vicki N.

    2008-01-01

    Müllerian Inhibiting Substance (MIS), a secreted glycoprotein in the Transforming Growth Factor-beta (TGF-beta) family of growth factors, mediates regression of the Müllerian ducts during embryonic sex differentiation in males. In Persistent Müllerian Duct Syndrome (PMDS), rather than undergoing involution, the Müllerian ducts persist in males, giving rise to the uterus, Fallopian tubes, and upper vagina. Genetic defects in MIS or its receptor (MISRII) have been identified in patients with PMDS. The phenotype in the canine model of PMDS derived from the miniature schnauzer breed is strikingly similar to that of human patients. In this model, PMDS is inherited as a sex-limited autosomal recessive trait. Previous studies indicated that a defect in the MIS receptor or its downstream signaling pathway was likely to be causative of the canine syndrome. In this study the canine PMDS phenotype and clinical sequelae are described in detail. Affected and unaffected members of this pedigree are genotyped, identifying a single base pair substitution in MISRII that introduces a stop codon in exon 3. The homozygous mutation terminates translation at 80 amino acids, eliminating much of the extracellular domain and the entire transmembrane and intracellular signaling domains. Findings in this model may enable insights to be garnered from correlation of detailed clinical descriptions with molecular defects, which are not otherwise possible in the human syndrome. PMID:18723470

  9. The sea-level highstand correlated to marine isotope stage (MIS) 7 in the coastal plain of the state of Rio Grande do Sul, Brazil.

    PubMed

    Lopes, Renato P; Dillenburg, Sergio R; Schultz, Cesar L; Ferigolo, Jorge; Ribeiro, Ana Maria; Pereira, Jamil C; Holanda, Elizete C; Pitana, Vanessa G; Kerber, Leonardo

    2014-12-09

    The coastal plain of the state of Rio Grande do Sul, in southern Brazil, includes four barrier-lagoon depositional systems formed by successive Quaternary sea-level highstands that were correlated to marine isotope stages (MIS) 11, 9, 5 and 1, despite the scarcity of absolute ages. This study describes a sea-level highstand older than MIS 5, based on the stratigraphy, ages and fossils of the shallow marine facies found in coastal barrier (Barrier II). This facies outcrops along the banks of Chuí Creek, it is composed of fine, well-sorted quartz sand and contains ichnofossils Ophiomorpha nodosa and Rosselia sp., and molluscan shells. The sedimentary record indicates coastal aggradation followed by sea-level fall and progradation of the coastline. Thermoluminescence (TL) and electron spin resonance (ESR) ages from sediments and fossil shells point to an age of ∼220 ka for the end of this marine transgression, thus correlating it to MIS 7 (substage 7e). Altimetric data point to a maximum amplitude of about 10 meters above present-day mean sea-level, but tectonic processes may be involved. Paleoceanographic conditions at the time of the highstand and correlations with other deposits in the Brazilian coasts are also discussed.

  10. The sea-level highstand correlated to marine isotope stage (MIS) 7 in the coastal plain of the state of Rio Grande do Sul, Brazil.

    PubMed

    Lopes, Renato P; Dillenburg, Sergio R; Schultz, Cesar L; Ferigolo, Jorge; Ribeiro, Ana Maria; Pereira, Jamil C; Holanda, Elizete C; Pitana, Vanessa G; Kerber, Leonardo

    2014-12-01

    The coastal plain of the state of Rio Grande do Sul, in southern Brazil, includes four barrier-lagoon depositional systems formed by successive Quaternary sea-level highstands that were correlated to marine isotope stages (MIS) 11, 9, 5 and 1, despite the scarcity of absolute ages. This study describes a sea-level highstand older than MIS 5, based on the stratigraphy, ages and fossils of the shallow marine facies found in coastal barrier (Barrier II). This facies outcrops along the banks of Chuí Creek, it is composed of fine, well-sorted quartz sand and contains ichnofossils Ophiomorpha nodosa and Rosselia sp., and molluscan shells. The sedimentary record indicates coastal aggradation followed by sea-level fall and progradation of the coastline. Thermoluminescence (TL) and electron spin resonance (ESR) ages from sediments and fossil shells point to an age of ∼220 ka for the end of this marine transgression, thus correlating it to MIS 7 (substage 7e). Altimetric data point to a maximum amplitude of about 10 meters above present-day mean sea-level, but tectonic processes may be involved. Paleoceanographic conditions at the time of the highstand and correlations with other deposits in the Brazilian coasts are also discussed.

  11. The Roosevelt Island Climate Evolution (RICE) Project - Did the Ross Ice Shelf Collapse During MIS 5e?

    NASA Astrophysics Data System (ADS)

    Bertler, N. A. N.; Conway, H.; Dahl-Jensen, D.; Blunier, T.; Brook, E.; Dadic, R.; Delmonte, B.; Dongqi, Z.; Edwards, R.; Emanuelsson, D. B.; Fudge, T. J.; Golledge, N.; Hindmarsh, R. C. A.; Hawley, R. L.; Kipfstuhl, S.; Kjær, H. A.; Kurbatov, A.; Lee, J.; Mayewski, P. A.; Naish, T.; Neff, P. D.; Scherer, R. P.; Severinghaus, J. P.; Simonsen, M. F.; Steig, E. J.; Tuohy, A.; Vallelonga, P. T.; Waddington, E. D.

    2014-12-01

    Geological evidence and modelling experiments suggest that the removal of ice shelves from marine based ice sheets can lead to catastrophic collapse. Roosevelt and Ross Islands are thought to be key stabilization anchors for the Ross Ice Shelf and thus the West Antarctic Ice Sheet. As part of the Roosevelt Island Climate Evolution (RICE) project, a 763m deep ice core was recovered during 2011-2013 from Roosevelt Island, at the northern edge of the Ross Ice Shelf. The ice at Roosevelt Island is grounded 210m below sea level and accumulates in situ, with the Ross Ice Shelf flowing around the rise. High resolution radar surveys show a well developed Raymond Bump at the divide of the ice dome. With the conclusion of the RICE core processing campaign in July 2014, a preliminary age model is developed using annual layer count, volcanic ash layers; and high resolution methane data tied to the WAIS Divide ice core record, and a glacial flow model. Here we show preliminary data spanning over 100 ka including evidence of ice from the Eemian period (MIS 5e) at the base of the core. The presence of Eemian ice in the RICE record raises the question: how much of the Ross Ice Shelf and West Antarctic Ice Sheet collapsed during the last interglacial, when global sea level was 4-8m higher than today? We discuss reconstructions of sea surface and air temperature, sea ice extent, atmospheric circulation patterns, and ice shelf retreat. An ensemble of sensitivity modelling experiments is used to determine thresholds for the removal of ice on Roosevelt Island and correlated grounding line and ice volume changes of the Ross Ice Shelf and the West Antarctic Ice Sheet.

  12. Millennial/submillennial-scale sea-level fluctuations in western Mediterranean during the second highstand of MIS 5e

    NASA Astrophysics Data System (ADS)

    Dabrio, C. J.; Zazo, C.; Cabero, A.; Goy, J. L.; Bardají, T.; Hillaire-Marcel, C.; González-Delgado, J. A.; Lario, J.; Silva, P. G.; Borja, F.; García-Blázquez, A. M.

    2011-02-01

    This paper investigates a series of small-scale, short-lived fluctuations of sea level registered in a prograding barrier spit that grew during the MIS 5e. This interglacial includes three highstands ( Zazo et al., 2003) and we focus on the second highstand, of assumed duration ˜10 ± 2 ka, given that U-Th ages do not provide more accurate data. Geometry and 3D architecture of beach facies, and thin-section petrography were used to investigate eight exposed offlapping subunits separated by seven conspicuous erosion surfaces, all interpreted as the result of repeated small-scale fluctuations of sea level. Each subunit records a relatively rapid rise of sea level that generated a gravelly shoreface with algal bioherms and a sandy uppermost shoreface and foreshore where most sand accumulated. A second range of still smaller-scaled oscillations of sea level has been deduced in this phase of sea-level fluctuation from lateral and vertical shifts of the foreshore-plunge-step-uppermost shoreface facies. Eventually, progradation with gently falling sea level took place and foreshore deposits underwent successive vadose cementation and subaerial dissolution, owing to relatively prolonged exposure. Later recovery of sea level re-established the highstand with sea level at approximately the same elevation, and there began deposition of a new subunit. The minimum sea-level variation (fall and subsequent rise) required to generate the observed features is 4 m. The time span available for the whole succession of events, and comparison with the Holocene prograding beach ridge complex in the nearby Roquetas (Almería) were used to calculate the periodicity of events. A millennial-suborbital time scale is suggested for fluctuations separating subunits and a decadal scale for the minor oscillations inside each subunit.

  13. A new age within MIS 7 for the Homo neanderthalensis of Saccopastore in the glacio-eustatically forced sedimentary successions of the Aniene River Valley, Rome

    NASA Astrophysics Data System (ADS)

    Marra, Fabrizio; Ceruleo, Piero; Jicha, Brian; Pandolfi, Luca; Petronio, Carmelo; Salari, Leonardo

    2015-12-01

    Field observations as well as borehole, sedimentological and geochronologic data allow us to reconstruct the geologic setting of the Aniene River Valley in northern Rome, framing it within the recently recognized picture of temporally constrained, glacio-eustatically forced aggradational successions of this region. The sedimentary successions cropping out in this area include those described in the literature of the early 20th century in Saccopastore, where two skulls of Homo neanderthalensis were recovered. Based on the geometry, elevation and sedimentologic features of the investigated sedimentary deposits, the stratigraphic record of Saccopastore is correlated with the aggradational succession deposited in response to sea-level rise during glacial termination III at the onset of MIS 7 (i.e. ∼250 ka), corresponding to the local Vitinia Formation, as opposed to previous correlation with the MIS 5 interglacial and a locally defined "Tyrrhenian" stage (∼130 ka). This previous attribution was based on the interpretation of the sedimentary succession of Saccopastore, occurring between 15 and 21 m a.s.l., as a fluvial terrace formed around 130 ka during the Riss-Würm interglacial, ca. 6 m above the present-day alluvial plain of the Aniene River. In contrast to this interpretation, a 40Ar/39Ar age of 129 ± 2 ka determined for this study on a pyroclastic-flow deposit intercalated in a fluvial-lacustrine sequence forming a terrace ∼37 m a.s.l. near the coast of Rome constrains the aggradational succession in this area to MIS 5, precluding the occurrence of an equivalent fluvial terrace at lower elevation in the inland sector of Saccopastore. We therefore interpret the stratigraphic record of Saccopastore as the basal portion of the aggradational succession deposited in response to sea-level rise during MIS 7, whose equivalent fluvial terrace occurs around 55 m a.s.l. in this region. We also review the published paleontological and paleoethnological records

  14. Palaeoecology of well-preserved coral communities in a siliciclastic environment from the Late Pleistocene (MIS 7), Kish Island, Persian Gulf (Iran): the development of low-relief reef frameworks (biostromes) in increasingly restricted environments

    NASA Astrophysics Data System (ADS)

    Mossadegh, Zahra Karimi; Parker, Justin; Gischler, Eberhard; Oschmann, Wolfgang; Blakeway, David; Eisenhauer, Anton

    2013-03-01

    Major changes in community structure and depositional relief of high-latitude coral communities in the southern Persian Gulf between marine isotope stage (MIS) 7 and the present day suggest that the area has become increasingly restricted. Corals and bivalves from outcrops on Kish Island, Iran, were identified in order to interpret the Late Pleistocene palaeoenvironmental setting. U/Th disequilibrium dating was used to constrain the ages of the stratigraphic units. During MIS 7, two coral-bearing sequences were deposited on what is now Kish Island. The lower sequence is dated as MIS 7.5 and changes laterally from an assemblage dominated by Cyphastrea sp. and Platygyra daedalea in the west to one characterized by branching Montipora in the east. By contrast, the upper sequence, dated as MIS 7.1, transitions from an assemblage dominated by platy Montipora in the west to a diverse assemblage of Platygyra and other faviids in the east. The assemblages of both sequences are within a marl matrix and bounded by thin lithified mollusc-rich layers. Corals and bivalves indicate that the sequences were deposited on gentle slopes in sheltered environments less than 20 m deep. The MIS 7 deposits may be classified as coral carpets or biostromes that developed a low-relief framework. During MIS 5, coral communities were no longer framework building and are now limited to an Acropora-rich layer of coral rubble that covers large parts of the island, and two small incipient reefs with sparse faviids. Similarities between the MIS 5 and modern nearshore coral communities suggest that the environmental conditions during MIS 5 were comparable to those of today. The late Pleistocene coral carpets and non-framework coral communities of the southern Persian Gulf may serve as models for coral biostromes in the fossil record, which formed under restricted environmental conditions such as elevated terrigenous input, high turbidity, and strong seasonal changes in temperature and/or salinity.

  15. (Mis)Understanding Radiation

    SciTech Connect

    Schreiber, Stephen Bruce

    2016-02-10

    This set of slides discusses radiation and fears concerning it at a non-technical level. Included are some misconceptions and practical consequences resulting from these. The concept of radiation hormesis is explained. The author concludes that a number of significant societal benefits are being foregone because of overly cautious concerns about low-level radiation.

  16. Late Quaternary landscape development at the margin of the Pomeranian phase (MIS 2) near Lake Wygonin (Northern Poland)

    NASA Astrophysics Data System (ADS)

    Hirsch, Florian; Schneider, Anna; Nicolay, Alexander; Błaszkiewicz, Mirosław; Kordowski, Jarosław; Noryskiewicz, Agnieszka M.; Tyszkowski, Sebastian; Raab, Alexandra; Raab, Thomas

    2015-04-01

    , Florian Hirsch, Anna Schneider, Alexander Nicolay, Mirosław Błaszkiewicz, Jarosław Kordowski, Agnieszka M. Noryskiewicz, Sebastian Tyszkowski, Alexandra Raab, Thomas Raab, Late Quaternary landscape development at the margin of the Pomeranian phase (MIS 2) near Lake Wygonin (Northern Poland), Pages 28-44, 2015, with permission from Elsevier.

  17. Long-term Paleomagnetic Secular Variation and Excursions from the western Equatorial Pacific Ocean (MIS2-4)

    NASA Astrophysics Data System (ADS)

    Lund, Steve; Schwartz, Martha; Stott, Lowell

    2017-01-01

    SUMMARYNew paleomagnetic results are presented for the Pleistocene (<span class="hlt">MIS</span>2-4) portion of deep-sea core MD98-2181 (MD81; Devao Gulf, Philippine Islands). MD81 is the highest resolution (˜50 cm/ky) PSV record for ˜12-70 ka ever recovered from Equatorial latitudes (±15°). Magnetic studies indicate that MD81 has a stable natural remanence (NRM) with directional uncertainties (MAD angles) typically less than 3°. We have also recovered a relative paleointensity estimate from these sediments based on normalization to SIRMs. We have correlated our relative paleointensity record with high-resolution relative paleointensity records from the North Atlantic Ocean (Lund et al., 2001a, b). The MD81 ages are always within ± 500 years of the North Atlantic records over the entire core. We also correlate our PSV record with another published PSV record from Indonesia (MD34; Blanchet et al., 2006). We are able to correlate 25 inclination features, 25 declination features, and 24 relative paleointensity features between MD81 and MD34. We identify three intervals of `anomalous' directions in the cores (based on > 2σ deviation from mean directions). One of these intervals contains true excursional directions and is dated to ˜40.5 ka. We associate this interval with the Laschamp Excursion (e.g., Bonhommet and Zahringer, 1969; Lund et al, 2005). We also note two other intervals that have anomalous directions, but no true excursional directions. These intervals occur around ˜34.5 ka and ˜61.5 ka and we associate them with the Mono Lake Excursion (˜33.5-34.5 ka) in western USA (e.g., Liddicoat and Coe, 1979) and the Norwegian-Greenland Sea Excursion (˜61 ± 2 ka) in the North Atlantic Ocean (e.g., Nowaczyk et al., 1994). We view our `anomalous' PSV in the three intervals to be truly anomalous even though most directions are not truly excursional. We think that it is time to reconsider the definition of what is `anomalous' PSV or excursions. To do that we need good</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/11146246','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/11146246"><span>Discriminative power of fatty acid methyl ester (FAME) analysis using the microbial identification system (<span class="hlt">MIS</span>) for Candida (Torulopsis) glabrata and Saccharomyces cerevisiae.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Peltroche-Llacsahuanga, H; Schmidt, S; Lütticken, R; Haase, G</p> <p>2000-12-01</p> <p>Candida (Torulopsis) glabrata is frequently isolated in cases of fungal infection and commonly shows acquired or innate fluconazole resistance. Saccharomyces cerevisiae, an emerging opportunistic yeast pathogen, causes serious systemic infections in immunocompromised, and vaginitis and superficial infections in immunocompetent patients. For both species reliable identification in the routine laboratory is mandatory, but species identification of strains, e.g. trehalose-negative C. glabrata, may be difficult. Therefore, gas-liquid chromatography (GLC) of whole cell fatty acid methyl ester (FAME) profiles, that is independent of assimilation profiles of strains and suitable for reliable and rapid identification of clinically important yeasts, was applied. However, frequent misidentification of C. glabrata as S. cerevisiae has been reported when using the Yeast Clinical Database of <span class="hlt">MIS</span>. Accuracy of <span class="hlt">MIS</span> identification may be strongly influenced by the amounts of cell mass analyzed. Therefore, the present study compared the <span class="hlt">MIS</span> results of these two yeasts achieved with different cell masses. Primarily we optimized, especially with respect to cost-effectiveness, the recommended streaking technique yielding a maximal recovery of 90-130 mg of cell mass from one plate, enabling testing of poor growing strains of C. glabrata. For all C. glabrata strains tested (n = 10) the highest identification scores (SI [Similarity Index] range 0.525-0.963, median 0.832) were achieved with 30 to 45 mg of cell mass. Only 5 of 10 S. cerevisiae strains revealed good library comparisons (SI > or = 0.5) when using 30 mg of cell mass, whereas with 45 mg all strains but two revealed this SI-level. For S. cerevisiae a higher amount of cell mass processed (up to 90 mg) was correlated with better identification scores (SI range using 90 mg: 0.464-0.870, median, 0.737). Several passages prior to FAME analysis of C. glabrata strains on recommended media revealed narrowing of SI ranges, but</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMPP53C1245C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMPP53C1245C"><span>Coccolithophores Productivity in the Iberian Margin During Marine Isotope Stage (<span class="hlt">MIS</span>) 11 and 12: Results from IODP Sites U1385 and U1391</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cavaleiro, C. D.; Rodrigues, T.; Marino, M.; Maiorano, P.; Flores, J. A.; Balestra, B.; Abrantes, F. F. G.; Ventura, C.; Li, B.; Hodell, D. A.; Voelker, A. H. L.; Kucera, M.; Baumann, K. H.; Stoll, H. M.</p> <p>2014-12-01</p> <p>Coccolithophores are a main phytoplankton group and among the most important pelagic calcifying organisms playing a key role in the ocean biogeochemistry and ecosystem, as primary producers and calcifiers. Reconstruction of coccolithophores productivity is critical for understanding past climate change and defining past levels of atmospheric CO2. Upwelling systems, such as the one along the Iberian margin, are important carbon sinks. Using the coccolith Sr/Ca ratio, a recent geochemistry-based proxy, we reconstructed coccolithophores productivity changes during <span class="hlt">MIS</span> 12 to 11 at IODP Sites U1385 and U1391, the latter closer to shore and under stronger upwelling influence. The <span class="hlt">MIS</span> 12 is considered the most extreme glacial of the last 1 Myr and <span class="hlt">MIS</span> 11 one of the longer lasting interglacial periods. Studying these two climatic extremes will allow a better constraining of the influence of upwelling on the coccolithophores community and understand their role in phytoplankton ecology and the carbon cycle. For a clear assessment the coccolith Sr/Ca data needs to be corrected for temperature and species composition changes and the extraction of these secondary influences were made using UK37 - SST and the coccolith community. Results for the Iberian margin showed higher coccolithophores productivity during the glacial period, and lower during the interglacial with an increasing trend during the glaciation and a steep decline during the deglaciation. Higher productivity during colder conditions might be associated to stronger winds that increased upwelling and/or the mixing of the upper water column and thus nutrient replenishment at the surface. These results will be placed into context of other proxy data from the Sites or region, e.g. TOC, total alkenones, diatom and coccolith abundances.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMPP43B2276R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMPP43B2276R"><span>Model-Paleodata analysis of an orbitally driven mechanism for the onset of the warmest interglacials like <span class="hlt">MIS</span> 11, 31, 49 etc.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Roychowdhury, R.; Deconto, R. M.</p> <p>2015-12-01</p> <p>Global climate during Quaternary and Late Pliocene (present-3.1 Ma) is characterized by alternating glacial and interglacial conditions. Recently, several interglacials have been identified as warmer than others, like 9, 11, 31, 49, 55, 77, 87 and 91, and are termed as "Superinterglacials". Our proposed theory associates these superinterglacials with variations in the behavior of the Northern Hemisphere (NH) ice sheets with respect to the Southern Hemisphere (SH) ice sheets. At lower eccentricities, with the effect of precession being minimal, the NH ice sheets vary in-phase with SH. At higher eccentricities, NH ice sheets vary out-of-phase with SH ice sheets and are forced by precession driven local insolation changes. Model results indicate that during periods of low eccentricity, favorable forcing (high obliquity, high CO2) leads to unusually long interglacial conditions in both NH and SH. Using an ensemble of GCM simulations covering <span class="hlt">MIS</span> 11, 31 and 49 we show that SH ice-sheets follow boreal summer insolation at lower eccentricities, switching to austral summer insolation at higher eccentricities. This switch provides the necessary orbital forcing for prolonged interglacial climates, much longer than expected from global oxygen isotope records. The prolonged warm conditions in the SH preconditions the poles to produce a large response during the superinterglacials. Recent paleodata studies have shown the existence of such extra-long interglacials in the NH during <span class="hlt">MIS</span> 15-13 (preceding <span class="hlt">MIS</span> 11) using grain-size records from Chinese loess (Q Hao, 2015). In this study we work with a collection of paleoclimate records though Pleistocene and correlate with our modeling results. Global records such as benthic δ18O capture the integrated signals of ice volume from both hemispheres, making it difficult to isolate the behaviour of the NH and SH ice sheets. Hence we focus on paleodata records, which capture the NH and SH ice volume signals individually, like the Chinese</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_11");'>11</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li class="active"><span>13</span></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_13 --> <div id="page_14" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="261"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMPP23C2317N','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMPP23C2317N"><span>Investigation into <span class="hlt">MIS</span> 11 in the U.S. Great Basin Using Trace Elements and Stable Isotopes from two Lehman Caves Stalagmites</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Neary, A.; McGee, D.; Tal, I.; Shakun, J. D.</p> <p>2015-12-01</p> <p>Marine Isotope Stage 11 (<span class="hlt">MIS</span> 11) represents a long interglacial period of high temperatures and muted orbital variability that occurred around 424-374 kya, and is referred to as a 'super-interglacial'. <span class="hlt">MIS</span> 11 is marked by especially pronounced high latitude warming in the Northern Hemisphere from 410-400 ka and thus presents a natural experiment for investigating the response of Great Basin precipitation to high latitude temperatures.<span class="hlt">MIS</span> 11 is recorded by stalagmites LC3 and BT1 from Lehman Caves in Great Basin National Park, Nevada. LC3 represents 378-413 ka, while BT1 has a bottom age of 410 ka. Ongoing U-Th dating will refine chronologies from these samples. We will present stable isotope (δ13C and δ18O) and trace element (Mg/Ca and Sr/Ca) data from these stalagmites to study changes in precipitation recorded in them. Previous studies have shown a relationship between Mg/Ca, Sr/Ca, δ13C and prior calcite precipitation, and thus infiltration rates, in the cave system (Cross et al., 2015; Steponaitis et al., 2015). Meanwhile, δ18O has been shown to reflect larger scale atmospheric circulation.We will compare the records to previously published trace element and stable isotope data from more recent interglacials (Lachniet et al., 2014; Cross et al., 2015; Steponaitis et al., 2015) to test whether extensive high-latitude warming during <span class="hlt">MIS</span> 11 was marked by anomalous precipitation patterns in the Great Basin. As they are coeval, we will also test the reproducibility between the stalagmites.References cited:Cross M., et al. (2015) Great Basin hydrology, paleoclimate, and connections with the North Atlantic: A speleothem stable isotope and trace element record from Lehman Caves, NV. Quaternary Science Reviews, in press.Steponaitis E., et al. (2015) Mid-Holocene drying the U.S. Great Basin recorded in Nevada speleothems. Quaternary Science Reviews, in press.Lachniet M. S., et al. (2014) Orbital control of western North America atmospheric circulation and climate</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMPP33C1254R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMPP33C1254R"><span><span class="hlt">MIS</span> 5e sea level: up to what point can we use literature reviews to answer the most pressing questions on the Last Interglacial ice sheets?</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rovere, A.; Raymo, M. E.</p> <p>2014-12-01</p> <p>During <span class="hlt">MIS</span> 5e (between ~128 and 116 kyr BP) greenhouse gas concentrations were comparable to pre-industrial levels, summer insolation was higher by ~10% at high latitudes and polar temperatures in both hemispheres were about 3-5 °C warmer than today. Sea level (SL) at this time has been a subject of numerous studies (and some debate) with ~1000 sites with <span class="hlt">MIS</span> 5e sea level markers recognized worldwide. Recently, Kopp et al. (Nature, 2009) and Dutton & Lambeck (Science, 2012) analyzed worldwide datasets of sea level markers pertaining to the last interglacial. After accounting for GIA, they reached similar conclusions that eustatic (i.e., globally averaged) sea level (ESL) was between +5 and +9.4 m above modern during <span class="hlt">MIS</span> 5e. Furthermore, Kopp et al. (Nature, 2009; GJI, 2013) suggest that sea level was not uniform during the LIG, but instead underwent at least two rapid oscillations including a rapid late 5e rise first proposed by Hearty et al. (QSR, 2007) and later by O'Leary et al. (Nat. Geo., 2013). Investigating the temporal and geographic variability of <span class="hlt">MIS</span> 5e sea level opens new lines of research, in particular the possibility to fingerprint (Hay et al., QSR, 2014) the source of the proposed rapid ice sheet collapse near the end of the Last Interglacial. In this presentation we ask: can we use a database of published sea level estimates for this purpose? To answer this question, we built a relative sea level (RSL) database using RSLcalc 2.0; this is a relational database specifically designed to review relative sea level data points while keeping all the relevant information contained in the original publications. RSlcalc allows to estimate the measurement error (on the actual elevation of the SL feature), the error on the indicative range (the elevation range occupied by a sea level indicator) as well as the reference water level (the relationship between the marker and the former sea level). We show that the majority of published data have an accuracy of few</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ChPhB..25h7304D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ChPhB..25h7304D"><span>Groove-type channel enhancement-mode AlGaN/GaN <span class="hlt">MIS</span> HEMT with combined polar and nonpolar AlGaN/GaN heterostructures</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Duan, Xiao-Ling; Zhang, Jin-Cheng; Xiao, Ming; Zhao, Yi; Ning, Jing; Hao, Yue</p> <p>2016-08-01</p> <p>A novel groove-type channel enhancement-mode AlGaN/GaN <span class="hlt">MIS</span> high electron mobility transistor (GTCE-HEMT) with a combined polar and nonpolar AlGaN/GaN heterostucture is presented. The device simulation shows a threshold voltage of 1.24 V, peak transconductance of 182 mS/mm, and subthreshold slope of 85 mV/dec, which are obtained by adjusting the device parameters. Interestingly, it is possible to control the threshold voltage accurately without precisely controlling the etching depth in fabrication by adopting this structure. Besides, the breakdown voltage (V B) is significantly increased by 78% in comparison with the value of the conventional <span class="hlt">MIS</span>-HEMT. Moreover, the fabrication process of the novel device is entirely compatible with that of the conventional depletion-mode (D-mode) polar AlGaN/GaN HEMT. It presents a promising way to realize the switch application and the E/D-mode logic circuits. Project supported by the National Science and Technology Major Project, China (Grant No. 2013ZX02308-002) and the National Natural Science Foundation of China (Grant Nos. 11435010, 61474086, and 61404099).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012QuRes..78..217L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012QuRes..78..217L"><span>Revised 14C dating of ice wedge growth in interior Alaska (USA) to <span class="hlt">MIS</span> 2 reveals cold paleoclimate and carbon recycling in ancient permafrost terrain</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lachniet, Matthew S.; Lawson, Daniel E.; Sloat, Alison R.</p> <p>2012-09-01</p> <p>Establishing firm radiocarbon chronologies for Quaternary permafrost sequences remains a challenge because of the persistence of old carbon in younger deposits. To investigate carbon dynamics and establish ice wedge formation ages in Interior Alaska, we dated a late Pleistocene ice wedge, formerly assigned to Marine Isotope Stage (<span class="hlt">MIS</span>) 3, and host sediments near Fairbanks, Alaska, with 24 radiocarbon analyses on wood, particulate organic carbon (POC), air-bubble CO2, and dissolved organic carbon (DOC). Our new CO2 and DOC ages are up to 11,170 yr younger than ice wedge POC ages, indicating that POC is detrital in origin. We conclude an ice wedge formation age between 28 and 22 cal ka BP during cold stadial conditions of <span class="hlt">MIS</span> 2 and solar insolation minimum, possibly associated with Heinrich event 2 or the last glacial maximum. A DOC age for an ice lens in a thaw unconformity above the ice wedge returned a maximum age of 21,470 ± 200 cal yr BP. Our variable 14C data indicate recycling of older carbon in ancient permafrost terrain, resulting in radiocarbon ages significantly older than the period of ice-wedge activity. Release of ancient carbon with climatic warming will therefore affect the global 14C budget.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2001SeScT..16..641R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2001SeScT..16..641R"><span>Interfacial charge trapping in extrinsic Y2O3/SiO2 bilayer gate dielectric based <span class="hlt">MIS</span> devices on Si(100)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rastogi, A. C.; Sharma, R. N.</p> <p>2001-08-01</p> <p>Metal-insulator-semiconductor (<span class="hlt">MIS</span>) structures based on an extrinsic Y2O3 dielectric film on Si show high leakage currents due to roughness-related highly localized fields. Oxygen annealing increases the dielectric constant and strength and reduces leakage currents by transforming Y2O3 (film)/Si(100) into a bilayer Y2O3 (film)/SiO2/Si(100) dielectric structure. Evolution of interfacial SiO2 causes generation of mid-gap interface states at Ev + 0.23 eV and Ev + 0.43 eV, which act as electron traps and are responsible for hysteresis effects in capacitance-voltage (C-V) and current-voltage (I-V) behaviour in the accumulation-inversion modes. The electron trapping reduces the cathodic field and causes lowering of the current and the shift in current to higher fields after successive ramps. The charge trapping effects cause varied and unstable C-V and I-V behaviour of <span class="hlt">MIS</span> structures based on a Y2O3/SiO2 bilayer gate dielectric. Its origin has been attributed to microstructure and defect state modification at the Y2O3 film-Si interface. This limits its application in high-density dynamic random access memory and ultra-large-scale integration devices.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3211223','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3211223"><span>Electrical behavior of <span class="hlt">MIS</span> devices based on Si nanoclusters embedded in SiOxNy and SiO2 films</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2011-01-01</p> <p>We examined and compared the electrical properties of silica (SiO2) and silicon oxynitride (SiOxNy) layers embedding silicon nanoclusters (Sinc) integrated in metal-insulator-semiconductor (<span class="hlt">MIS</span>) devices. The technique used for the deposition of such layers is the reactive magnetron sputtering of a pure SiO2 target under a mixture of hydrogen/argon plasma in which nitrogen is incorporated in the case of SiOxNy layer. Al/SiOxNy-Sinc/p-Si and Al/SiO2-Sinc/p-Si devices were fabricated and electrically characterized. Results showed a high rectification ratio (>104) for the SiOxNy-based device and a resistive behavior when nitrogen was not incorporating (SiO2-based device). For rectifier devices, the ideality factor depends on the SiOxNy layer thickness. The conduction mechanisms of both <span class="hlt">MIS</span> diode structures were studied by analyzing thermal and bias dependences of the carriers transport in relation with the nitrogen content. PMID:21711698</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016QSRv..152...72P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016QSRv..152...72P"><span>Global ice volume during <span class="hlt">MIS</span> 3 inferred from a sea-level analysis of sedimentary core records in the Yellow River Delta</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Pico, Tamara; Mitrovica, Jerry X.; Ferrier, Ken L.; Braun, Jean</p> <p>2016-11-01</p> <p>Estimates of global ice volume during the glacial phase of the most recent ice age cycle are characterized by significant uncertainty, reflecting the relative paucity of geological constraints on sea level relevant to this time interval. For example, during the middle stages of Marine Isotope Stage 3, published estimates of peak global mean sea level (GMSL) relative to the present range from -25 m to -87 m. The large uncertainty in GMSL at <span class="hlt">MIS</span> 3 has significant implications for estimates of the rate of ice growth in the period leading to the Last Glacial Maximum (∼26 ka). We refine estimates of global ice volume during <span class="hlt">MIS</span> 3 by employing sediment cores in the Bohai and Yellow Sea that record a migration of the paleoshoreline at ∼50-37 ka through a transition from marine to brackish conditions. In particular, we correct relative sea level at these sites for contamination due to glacial isostatic adjustment using a sea-level calculation that includes a gravitationally self-consistent treatment of sediment redistribution and compaction, and estimate a peak global mean sea level of -38 ± 7 m during the interval 50-37 ka. With suitable sedimentary core records, the approach described herein can be extended to refine existing constraints on global ice volume across the entire glacial period.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012EGUGA..14.8461P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012EGUGA..14.8461P"><span>Lake Prespa palaeoenvironment since the <span class="hlt">MIS</span> 5: a continuous record from a mid-altitude site on modern human's way to Europe.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Panagiotopoulos, K.; Aufgebauer, A.; Schäbitz, F.; Wagner, B.</p> <p>2012-04-01</p> <p>Lake Prespa is situated in the Balkans (40°57'50'' N, 20°58'41'' E) along the eastern trajectory of modern human dispersal. A long (c. 18m) composite sediment core was investigated using geophysical, geochemical and pollen analyses. This study aims to reconstruct the palaeoenvironment and palaeoclimate from a mid-altitude (849m asl) site and evaluate their implications in the migration of our ancestors from Africa to Europe. The age-depth model, based on radiocarbon dating and tephrochronology, indicates continuous sedimentation reaching back to <span class="hlt">MIS</span> 5. According to the pollen record, the wider Lake Prespa catchment sustained refugial temperate tree populations throughout this period. Following the decline of woodlands at the end of <span class="hlt">MIS</span> 5, pollen concentration and TOC percentages retain relatively low values until the onset of the Holocene when closed forest formations dominated the landscape signaling the establishment of a warmer and moister climate. Distinct fluctuations of arboreal relative percentages coupled with the occurrence of TIC and Mn peaks can be tentatively correlated to Heinrich events. Climatic oscillations are sensitively recorded in the Lake Prespa sediments at a sub-millennial scale permitting a detailed reconstruction of the regional palaeoenvironment, as well as correlations with other regional and global climate archives. This project is part of the Collaborative Research Center 806: "Our Way To Europe; Culture-Environment Interaction and Human Mobility in the Late Quaternary" (www.sfb806.de). Keywords: Lake Prespa, Balkans, eastern Mediterranean, pollen analysis, palaeolimnology, modern human dispersal</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..1811085G','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..1811085G"><span>Marine-to-lacustrine transition, mud volcanism, and slope instability in an active tectonic setting: the <span class="hlt">MIS</span> 5 to 4 transition in the Sea of Marmara, Turkey</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Grall, Céline; Henry, Pierre; Kendé, Julia; Namık Çaǧatay, M.; Kadir Eriş, K.; Paillès, Christine; Sorlien, Christopher; Shillington, Donna; McHugh, Cecilia; Steckler, Michael; Çifçi, Günay; Géli, Louis</p> <p>2016-04-01</p> <p> MTDs. At the transition from Marine Isotope Stage (<span class="hlt">MIS</span>) 5 to 4, sea-level fell from 25 to 85 m below the modern sea-level resulting in the disconnection of the Sea of Marmara. Sapropels deposited on the shelf before the disconnection and are attributed to <span class="hlt">MIS</span>-5 (Cagatay et al. 2009). Grall et al, (2014) proposed that MTDs found above the Red-H1 were deposited at the beginning of <span class="hlt">MIS</span>-4 at ~70 ka and that MTD complexes found during earlier glacial cycles also accumulated after marine to lacustrine-disconnections, possibly in relation with hydrate dissociation and/or clay swelling. Buried mud volcanoes located within the NNAF damage zone pierce the Red-H1 reflector but not the reflector above, suggesting that the last main eruption may also happens at the beginning of <span class="hlt">MIS</span>-4. We will present preliminary assessment of the paleoenvironmental changes across the <span class="hlt">MIS</span>-5 to 4 transition from bio-indicators and geochemistry.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015RuPhJ..58..970V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015RuPhJ..58..970V"><span>Effect of Pulse Nanosecond Volume Discharge in Air at Atmospheric Pressure on Electrical Properties of <span class="hlt">Mis</span> Structures Based on p-HgCdTe Grown by Molecular Beam Epitaxy</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Voitsekhovskii, A. V.; Nesmelov, S. N.; Dzyadukh, S. M.; Grigor'ev, D. V.; Tarasenko, V. F.; Shulepov, M. A.</p> <p>2015-11-01</p> <p>The effect of the pulse nanosecond volume discharge in air at atmospheric pressure on the admittance of <span class="hlt">MIS</span> structures based on MBE graded-gap p-Hg0.78Cd0.22Te is studied in a wide range of frequencies and temperatures. It is shown that the impact of the discharge leads to significant changes in electrical characteristics of <span class="hlt">MIS</span> structures (the density of positive fixed charge increases), to the changes in the nature of the hysteresis of capacitance-voltage characteristics, and to an increase in the density of surface states. A possible reason for the changes in the characteristics of <span class="hlt">MIS</span> structures after exposure to the discharge is substantial restructuring of the defect-impurity system of the semiconductor near the interface.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010EGUGA..1213023S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010EGUGA..1213023S"><span>The period from the Last Interglacial to the Last Glacial Maximum (<span class="hlt">MIS</span> 5 - 2) in different archives of southern Italy</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sauer, Daniela; Wagner, Stephen; Al-Sharif, Riyad; Brückner, Helmut; Scarciglia, Fabio; Mastronuzzi, Giuseppe; Stahr, Karl</p> <p>2010-05-01</p> <p> to the sea level, in lagoonal to alluvial environments. There are only few age estimates available. Several shells from the lower terraces are currently being dated. A Calcic Luvisol developed on the terrace T1 (terminology according to Brückner, 1980), which is attributed to <span class="hlt">MIS</span> 5.1. The next higher terraces T2 and T3 are characterised by progressive soil evolution, in particular increasing rubification and clay translocation. In some locations, loess accumulated on the terraces, as observed in the profile Petrulla on T1. According to OSL datings by Zander et al. (2006), the loess at this site accumulated between 24.9 ka BP and <16 ka BP, i.e. during the LGM. A yellowish-brown Calcic Luvisol developed in the loess. Thus, the soils reflect rather the interglacial soil formation in a Mediterranean environment than the glacial soil formation in a steppe environment. References Allen, J.R.M., Watts, W.A., Huntley, B. (2000): Weichelian palynostratigraphy, palaeovegetation and palaeoenvironment; the record from Lago Grande di Monticchio, southern Italy. Quaternary International, 73/74: 91-110. Brückner, H., 1980. Marine Terrassen in Süditalien. Eine quartärmorphologische Studie über das Küstentiefland von Metapont. Düsseldorfer Geographische Schriften, 14, 235 p. Di Donato, V., Esposito, P., Russo-Ermolli, E., Scarano, A., Cheddadi, R. (2008): Coupled atmospheric and marine palaeoclimatic reconstruction for the last 35 ka in the Sele Plain - Gulf of Salerno area (southern Italy). Quaternary International, 190: 146-157. Follieri, M., Giardini, M., Magri, D., Sadori, L. (1998): Palynostratigraphy of the last glacial period in the volcanic region of central Italy. Quaternary International, 47/48: 3-20. Zander, A., Fülling, A., Brückner, H. & Mastronuzzi, G. (2006): OSL dating of Upper Pleistocene littoral sediments: a contribution to the chronostratigraphy of raised marine terraces bordering the Gulf of Taranto, South Italy. Geografia Fisica e Dinamica Quaternaria</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005AGUFMPP43C..02H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005AGUFMPP43C..02H"><span>Geological "Ground Truth" of Sea-level Highstand Events During Warm Interglaciations (<span class="hlt">MIS</span> 11 and 5e): Taking the Punch out of Proxy Precision</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hearty, P. J.</p> <p>2005-12-01</p> <p>High-resolution sea-level records for marine isotope stages (<span class="hlt">MIS</span>) 11 and 5e from coastal outcrops in Bahamas, Bermuda, Hawaii, and Western Australia provide physical confirmation of extreme ice-melting events during Pleistocene interglacials. Field evidence indicates <span class="hlt">MIS</span> 11 sea level rose in a series of oscillations to c. +20 m, while that of <span class="hlt">MIS</span> 5e reached its maximum of +6-10 m. Because these were brief events (100s yrs), their true magnitude is generally muted or obscured in deep-sea oxygen isotope records; generally averaged over thousands of years by the combined effects of sampling, bioturbation, and sedimentation rates. Further unresolvable variables such as temperature and salinity further cloud the isotope proxy record. Thus, the tangible rock record is of greatest importance in understanding the nature of these extreme events. Geomorphology, sedimentary structures, taphonomy of and dating of organisms, and petrology provide ground truth at field sites. Sea-level highstands preserve terraces and benches by erosion and subsequent deposition of sub- and intertidal sediments. Fenestral porosity is a measure of intertidal wetting and drying of sand, while decimetre-scale, high-angle cross beds of poorly-sorted sand and gravel indicate shallow subtidal conditions. In situ coral heads describe similar subtidal conditions. Delicate, sometimes partially articulated skeletons of birds and reptiles in sea caves reveal a protected shoreline. An early generation of isopachous, fibrous cement verifies the presence of marine phreatic water over a sustained period of time. These features, often misinterpreted (McMurtry, 2004, AGU Fall Meeting, OS21E-06), categorically exclude emplacement by tsunami waves. Oceanic isotope records cannot produce an equivalent level of resolution of short, extreme events via (in terms of age, duration, rates of sea-level and ice-volume changes), thus shifting the `burden of proof' to proxy methods to identify such events. In our quest to</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://pubs.er.usgs.gov/publication/70030061','USGSPUBS'); return false;" href="http://pubs.er.usgs.gov/publication/70030061"><span>A multiple-approach radiometric age estimate for the Rotoiti and Earthquake Flat eruptions, New Zealand, with implications for the <span class="hlt">MIS</span> 4/3 boundary</span></a></p> <p><a target="_blank" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Wilson, C.J.N.; Rhoades, D.A.; Lanphere, M.A.; Calvert, A.T.; Houghton, B.F.; Weaver, S.D.; Cole, J.W.</p> <p>2007-01-01</p> <p>Pyroclastic fall deposits of the paired Rotoiti and Earthquake Flat eruptions from the Taupo Volcanic Zone (New Zealand) combine to form a widespread isochronous horizon over much of northern New Zealand and the southwest Pacific. This horizon is important for correlating climatic and environmental changes during the Last Glacial period, but has been the subject of numerous disparate age estimates between 35.1??2.8 and 71??6 ka (all errors are 1 s.d.), obtained by a variety of techniques. A potassium-argon (K-Ar) age of 64??4 ka was previously determined on bracketing lavas at Mayor Island volcano, offshore from the Taupo Volcanic Zone. We present a new, more-precise 40Ar/39Ar age determination on a lava flow on Mayor Island, that shortly post-dates the Rotoiti/Earthquake Flat fall deposits, of 58.5??1.1 ka. This value, coupled with existing ages from underlying lavas, yield a new estimate for the age of the combined eruptions of 61.0??1.4 ka, which is consistent with U-Th disequilibrium model-age data for zircons from the Rotoiti deposits. Direct 40Ar/39Ar age determinations of plagioclase and biotite from the Rotoiti and Earthquake Flat eruption products yield variable values between 49.6??2.8 and 125.3??10.0 ka, with the scatter attributed to low radiogenic Ar yields, and/or alteration, and/or inheritance of xenocrystic material with inherited Ar. Rotoiti/Earthquake Flat fall deposits occur in New Zealand in association with palynological indicators of mild climate, attributed to Marine Isotope Stage (<span class="hlt">MIS</span>) 3 and thus used to suggest an age that is post-59 ka. The natures of the criteria used to define the <span class="hlt">MIS</span> 4/3 boundary in the Northern and Southern hemispheres, however, imply that the new 61 ka age for the Rotoiti/Earthquake Flat eruption deposits will provide the inverse, namely, a more accurate isochronous marker for correlating diverse changes across the <span class="hlt">MIS</span> 4/3 boundary in the southwest Pacific. ?? 2007 Elsevier Ltd. All rights reserved.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016EGUGA..1811963T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016EGUGA..1811963T"><span>Burried <span class="hlt">MIS</span> 5 abrasion platforms in the Bay of Koper (Gulf of Trieste, Northern Adriatic) confirm long-term subsidence of the Northern Adriatic region</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Trobec, Ana; Šmuc, Andrej; Poglajen, Sašo; Vrabec, Marko</p> <p>2016-04-01</p> <p>The youngest seafloor sediments of the Gulf of Trieste (Northern Adriatic) are represented by an up to several 100 meters thick succession of Pliocene to Quaternary continental and shallow-marine deposits recording numerous transgressive-regressive cycles. These sediments are separated from older lithologies (mainly Eocene flysch) by an erosional unconformity. Previous geophysical campaigns conducted in the Italian part of the Gulf of Trieste revealed a complex undulating morphology of the unconformity characterised by numerous morphological steps in the flysch appearing between 40 and 200 m below sea level. From correlation with onshore well data from the Friuli and Veneto area it is assumed that the highest system of these unconformities located at approximately 40 mbsl represents a marine abrasion platform formed during the <span class="hlt">MIS</span> 5 period sea-level highstand. We present the first observations of these abrasion platforms in the Bay of Koper in the southern (Slovenian) part of the Gulf of Trieste. A series of perpendicular sub-bottom sonar profiles with a spacing of 250-500 meters was acquired in the Bay of Koper between 2009 and 2012 with the Innomar parametric sediment echo sounder SES-2000. Along the northern coast of the bay several acoustic facies were resolved, including the top erosional unconformity surface of the flysch. On this surface we located platforms at 35 ms (platform A), 40 ms (platform B) and 50 ms (platform C) of two-way-travel time. The top of abrasion platform B coincides with the top of a sediment progradational wedge which overlies abrasion platform C. No progradational wedge is developed at the top of platform A. Due to signal attenuation and multiples sub-bottom profiles could not be interpreted below 53 ms TWT time. We used a sound velocity of 1650 m/s for the time to depth conversion, which places the platforms at the depth of 28, 33 and 41 mbsl, respectively. Assuming that the abrasion platforms are a remnant of the <span class="hlt">MIS</span> 5 highstand, this</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011QSRv...30..769J','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011QSRv...30..769J"><span>Last glacial pollen record from Lanzhou (Northwestern China) and possible forcing mechanisms for the <span class="hlt">MIS</span> 3 climate change in Middle to East Asia</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Jiang, Hanchao; Mao, Xue; Xu, Hongyan; Thompson, Jessica; Wang, Ping; Ma, Xiaolin</p> <p>2011-03-01</p> <p>The vegetation on the northeastern margin of the Tibetan Plateau is highly sensitive to climatic changes and thus represents a potentially interesting environmental archive. Pollen samples from the Fanjiaping Loess section in Lanzhou on the western Chinese Loess Plateau (CLP) were analyzed in conjunction with OSL dating. The results indicate that pollen zone B (60.6-46.0 ka, correlative to the early <span class="hlt">MIS</span> 3) had the greatest abundances of Cupressaceae, Tsuga, Gramineae and Cyperaceae of the entire section, suggesting a warm phase during the last glacial period. These pollen taxa decreased significantly in abundance in the zones C (46.0-39.0 ka) and D (39.0-27.0 ka), reflecting a substantial climate cooling from the middle <span class="hlt">MIS</span> 3 to <span class="hlt">MIS</span> 2. These results correlate with climate records from the South China Sea, the CLP, Baikal Lake, North America, North Atlantic Ocean and other regions, and probably correspond with the decline of northern high-latitude insolation and the increase of global ice volume from 50 to 20 ka. In particular, arboreal pollen, fern spore and algae abundances declined sharply since ˜40 ka, while shrub and herb pollen reached the highest abundances. Conifer pollen Picea and Abies abundance also rose markedly and increased up the section. This implies significant climate deterioration and likely corresponded with substantial growth of the polar ice sheets since ˜40 ka. The decreasing temperature caused by an insolation decline during the last glacial period probably reinforced the cooling effect in a 'snow/ice/albedo' feedback, which would result in less climate sensitivity to radiative forcing. Meanwhile, vegetation decline in the Northern Hemisphere during the last glacial period and tundra development at high latitudes possibly caused additional cooling, enhancing the growth of polar ice sheets since 40 ka. The development of polar ice sheets increased the polar-to-equator temperature and pressure gradients, strengthening the westerlies and</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/6565326','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/6565326"><span>Study of gap states in a-Si:H alloys by measurements of photoconductivity and spectral response of <span class="hlt">MIS</span> solar cells</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Vanier, P.E.; Delahoy, A.E.; Griffith, R.W.</p> <p>1981-01-01</p> <p>A picture of the density of gap states n(E) in glow discharge a-Si:H is constructed using four different kinds of transport measurement on a large number of samples. The minimum in n(E) lies 0.4 eV below E/sub c/, rather than in the middle of the gap. A distribution of fast recombination centers lies at mid-gap, and two sets of hole traps lie between mid-gap and the valence band. Modifications in n(E) have been studied by the effects of selected impurities on the conversion efficiency and spectral response of <span class="hlt">MIS</span> and p-i-n solar cells.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009AGUFMPP43A1552R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009AGUFMPP43A1552R"><span>Application of ICP-SFMS, ICP-AES integrate method to the geochemical characterization of ANDRILL-<span class="hlt">MIS</span> oceanic sediment samples</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rugi, F.; Castellano, E.; Marino, F.; Ghedini, C.; Severi, M.; Becagli, S.; Traversi, R.; Udisti, R.</p> <p>2009-12-01</p> <p>An integrated system for the determination of 39 major and trace (including Rare Earths Elements -REE) metals in soils and marine sediments was set up by using Inductively Coupled Plasma - Sector Field Mass Spectrometry (ICP-SFMS) and Inductively Coupled Plasma - Atomic Emission Spectrophotometry (ICP - AES) devices, in order to achieve an extensive geochemical characterization. Major elements, in particular silicon, are also quantified with PIXE technique. Method selectivity, accuracy and reproducibility was evaluated analyzing six certified materials: Basalt, Hawaiian Volcanic Observatory (BHVO-1); Japanese Andesite (JA-2); Montana Soil (NIST 2711); Antarctic Sediment (CRM-MURST-ISS-A1); Antarctic Sediment (GBW 073113) e Antarctic Sediment (NIST 2702); after mineralization with fluoridric, nitric and perchloric acids on hot plate. The choice of the isotope (ICP-SFMS) or wavelength (ICP-AES) was addressed obtaining the best compromise between high sensitivity and suitable selectivity for the metal determination. Particular care was paid in optimizing analytical quantification of each species, because of the huge difference in concentration of major and trace elements in geological samples. For ICP-SFMS, high resolution (10,000 m/Δm) was selected for all metals to avoid isobaric interferences. An accurate blank evaluation was carried out, especially for metals present at sub-ppb levels in the extract solutions (REE and other trace elements). The obtained operative blank values included sample manipulation and digestion, reagent content and analytical procedures. ICP-SFMS and ICP-AES methods were applied to the characterization of the geochemical composition of sample from the first 90 m of Mc Murdo Ice Shelf (<span class="hlt">MIS</span>) marine core, in the framework of the ANDRILL (ANtarctic DRILLing) Project. This international project aims to study the role of the Antarctic Continent within the global climatic system, by the recovery and analysis of two deep sediment cores (named <span class="hlt">MIS</span></p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22469819','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22469819"><span>Capacitance-voltage characteristics of (Al/Ti)/Al{sub 2}O{sub 3}/n-GaN <span class="hlt">MIS</span> structures</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ivanov, P. A. Potapov, A. S.; Nikolaev, A. E.; Lundin, V. V.; Sakharov, A. V.; Tsatsulnikov, A. F.; Afanas’ev, A. V.; Romanov, A. A.; Osachev, E. V.</p> <p>2015-08-15</p> <p>The capacitance-voltage characteristics of (Al/Ti)/Al{sub 2}O{sub 3}/n-GaN metal—insulator-semiconductor (<span class="hlt">MIS</span>) structures are measured and analyzed. n-Type GaN films are grown on sapphire (0001) substrates by the metal-organic chemical vapor deposition method. An aluminum-oxide layer with a thickness of 60 nm is deposited onto the surface of GaN by the method of atomic-layer deposition from the gas phase. Metallic contacts are deposited by the electron-beam evaporation of titanium and aluminum in vacuum. According to the measurement results, the breakdown-field strength of the oxide, its dielectric constant, and the integrated electron density of states at the oxide-semiconductor interface are 5 × 10{sup 6} V/cm, 7.5, and 3 × 10{sup 12} cm{sup −2}, respectively.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006SeScT..21..335C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006SeScT..21..335C"><span>Analysis of interface states of Al/TiO2/Si0.3Ge0.7 <span class="hlt">MIS</span> structures using the conductance technique</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Chakraborty, S.; Bera, M. K.; Bose, P. K.; Maiti, C. K.</p> <p>2006-03-01</p> <p>TiO2 films have been deposited at a low temperature (~150 °C) using titanium tetrakis isopropoxide (TTIP) as an organometallic precursor on Si0.3Ge0.7 heterolayers by a microwave plasma-enhanced chemical vapour deposition system. Interfacial properties of the as-deposited films have been characterized using capacitance-voltage and conductance-voltage techniques measured at different frequencies. The energy distribution of interface states and the relaxation time have been determined from Gp/ω versus ω analysis. A Dit level of Al/TiO2/SiGe <span class="hlt">MIS</span> capacitors in the range of 2.87 × 1011 eV-1 cm-2 (in EC-0.446) eV to 5.04 × 1011 eV-1 cm-2 (in EC-0.696) eV has been observed from conductance measurements.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/22492338','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/22492338"><span>Temperature dependent electrical characterisation of Pt/HfO{sub 2}/n-GaN metal-insulator-semiconductor (<span class="hlt">MIS</span>) Schottky diodes</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Shetty, Arjun Vinoy, K. J.; Roul, Basanta; Mukundan, Shruti; Mohan, Lokesh; Chandan, Greeshma; Krupanidhi, S. B.</p> <p>2015-09-15</p> <p>This paper reports an improvement in Pt/n-GaN metal-semiconductor (MS) Schottky diode characteristics by the introduction of a layer of HfO{sub 2} (5 nm) between the metal and semiconductor interface. The resulting Pt/HfO{sub 2}/n-GaN metal-insulator-semiconductor (<span class="hlt">MIS</span>) Schottky diode showed an increase in rectification ratio from 35.9 to 98.9(@ 2V), increase in barrier height (0.52 eV to 0.63eV) and a reduction in ideality factor (2.1 to 1.3) as compared to the MS Schottky. Epitaxial n-type GaN films of thickness 300nm were grown using plasma assisted molecular beam epitaxy (PAMBE). The crystalline and optical qualities of the films were confirmed using high resolution X-ray diffraction and photoluminescence measurements. Metal-semiconductor (Pt/n-GaN) and metal-insulator-semiconductor (Pt/HfO{sub 2}/n-GaN) Schottky diodes were fabricated. To gain further understanding of the Pt/HfO{sub 2}/GaN interface, I-V characterisation was carried out on the <span class="hlt">MIS</span> Schottky diode over a temperature range of 150 K to 370 K. The barrier height was found to increase (0.3 eV to 0.79 eV) and the ideality factor decreased (3.6 to 1.2) with increase in temperature from 150 K to 370 K. This temperature dependence was attributed to the inhomogeneous nature of the contact and the explanation was validated by fitting the experimental data into a Gaussian distribution of barrier heights.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_12");'>12</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li class="active"><span>14</span></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_14 --> <div id="page_15" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="281"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3625184','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3625184"><span>Mitotic Spindle Defects and Chromosome <span class="hlt">Mis</span>-Segregation Induced by LDL/Cholesterol—Implications for Niemann-Pick C1, Alzheimer’s Disease, and Atherosclerosis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Granic, Antoneta; Potter, Huntington</p> <p>2013-01-01</p> <p>Elevated low-density lipoprotein (LDL)-cholesterol is a risk factor for both Alzheimer’s disease (AD) and Atherosclerosis (CVD), suggesting a common lipid-sensitive step in their pathogenesis. Previous results show that AD and CVD also share a cell cycle defect: chromosome instability and up to 30% aneuploidy–in neurons and other cells in AD and in smooth muscle cells in atherosclerotic plaques in CVD. Indeed, specific degeneration of aneuploid neurons accounts for 90% of neuronal loss in AD brain, indicating that aneuploidy underlies AD neurodegeneration. Cell/mouse models of AD develop similar aneuploidy through amyloid-beta (Aß) inhibition of specific microtubule motors and consequent disruption of mitotic spindles. Here we tested the hypothesis that, like upregulated Aß, elevated LDL/cholesterol and altered intracellular cholesterol homeostasis also causes chromosomal instability. Specifically we found that: 1) high dietary cholesterol induces aneuploidy in mice, satisfying the hypothesis’ first prediction, 2) Niemann-Pick C1 patients accumulate aneuploid fibroblasts, neurons, and glia, demonstrating a similar aneugenic effect of intracellular cholesterol accumulation in humans 3) oxidized LDL, LDL, and cholesterol, but not high-density lipoprotein (HDL), induce chromosome <span class="hlt">mis</span>-segregation and aneuploidy in cultured cells, including neuronal precursors, indicating that LDL/cholesterol directly affects the cell cycle, 4) LDL-induced aneuploidy requires the LDL receptor, but not Aß, showing that LDL works differently than Aß, with the same end result, 5) cholesterol treatment disrupts the structure of the mitotic spindle, providing a cell biological mechanism for its aneugenic activity, and 6) ethanol or calcium chelation attenuates lipoprotein-induced chromosome <span class="hlt">mis</span>-segregation, providing molecular insights into cholesterol’s aneugenic mechanism, specifically through its rigidifying effect on the cell membrane, and potentially explaining why ethanol</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016Geomo.274..116C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016Geomo.274..116C"><span>Millennial-scale climatic fluctuation in the fluvial record during <span class="hlt">MIS</span>3: Very high-resolution seismic images from NE Hungary</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cserkész-Nagy, Ágnes; Sztanó, Orsolya</p> <p>2016-12-01</p> <p>Alluvial architectures of a meandering river existing in <span class="hlt">MIS</span>3 were observed on very high-resolution (VHR) single-channel waterborne seismic profiles, 20-30 m below the Tisza River in the Pannonian Basin (Hungary). The study investigated the spatial and temporal variations of two, more than 2 km-long continuous series of inclined reflections interpreted as laterally accreted point bar complexes. The phases of natural meander migration were reconstructed in 3D based on the changes in the geometry and dip of the inclined reflections. A channel-forming discharge curve extending over approximately 2.5 ky was calculated by using paleo-width and depth data derived from the lateral accretion surfaces. Systematic analysis of the geometrical variations coupled with the discharge curve evaluation on each point bar complexes indicates millennial-scale discharge fluctuations 40-50 ky ago, to that the river responded principally by incision and infilling. The primary periodicity, comparable to the sub-Milankovitch cycles, is superimposed by shorter periods: ca. 500-year cycles reflect the phases of unidirectional meander development, while the smallest ones reflect the recurrence interval (150-200 years) of the highest floods. River-bed incisions happened step-by-step related to extreme floods, when the meander development also changed. The smaller-scale and more rapid fluctuations within a development unit were represented in variations of the channel width. Although the poor geochronology of the sandy fluvial deposits cannot allow any direct correlation to the climatostratigraphic events, the millennial-scale climate variations of <span class="hlt">MIS</span>3 were pronouncedly characteristic in the discharge fluctuations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2012QSRv...47...73B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2012QSRv...47...73B"><span>Characterization of a rapid climate shift at the <span class="hlt">MIS</span> 8/7 transition in central Spain (Valdocarros II, Autonomous Region of Madrid) by means of the herpetological assemblages</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Blain, Hugues-Alexandre; Panera, Joaquin; Uribelarrea, David; Rubio-Jara, Susana; Pérez-González, Alfredo</p> <p>2012-07-01</p> <p>Climate instability with high-amplitude and rapid shifts during the Middle Pleistocene is well known from pollen records and deep-ocean sediment cores. Although poorly correlatable with such long climate/environment records, the successive fossil amphibian and reptile assemblages from the Middle Pleistocene site of Valdocarros II (Autonomous Region of Madrid, central Spain) provide a unique opportunity to characterize the climatic and environmental features of such rapid (certainly less than 1000 years) shifts from cold to warm conditions in a terrestrial sequence. As the amphibians and reptiles do not differ at species level from the extant herpetofauna of the Iberian Peninsula, they can contribute to the reconstruction of the landscape and climate. In this paper, the mutual climatic range and habitat weighting methods are applied to the herpetofaunistic assemblages in order to estimate quantitative data. The difference in mean annual temperature between "cold" and "warm" periods is estimated at 3.2 °C, with a greater increase in temperature during winter (+3 °C) than during summer (+1 °C). During "cold" periods the climate was more Oceanic (although preserving some dryness during the summers), whereas during "warm" periods the climate became Mediterranean (with mild winters and a long period of dryness in the summer and early autumn). Though higher during cold periods, the continentality (or atmospheric temperature range) remained roughly similar, in accordance with the geographical location of the site in the centre of the Iberian Peninsula. A greater amount of open landscape occurred during "cold" periods, whereas during "warm" periods the wooded areas expanded from 20% to 40% of the landscape surface. Such climatic/environmental changes, together with the numeric datings of the site, suggest that this shift may correspond to the transition from <span class="hlt">MIS</span> 8 to <span class="hlt">MIS</span> 7, also called Termination III.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016BGeo...13.2757Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016BGeo...13.2757Z"><span>Aligning and synchronization of <span class="hlt">MIS</span>5 proxy records from Lake Ohrid (FYROM) with independently dated Mediterranean archives: implications for DEEP core chronology</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zanchetta, Giovanni; Regattieri, Eleonora; Giaccio, Biagio; Wagner, Bernd; Sulpizio, Roberto; Francke, Alex; Vogel, Hendrik; Sadori, Laura; Masi, Alessia; Sinopoli, Gaia; Lacey, Jack H.; Leng, Melanie J.; Leicher, Niklas</p> <p>2016-05-01</p> <p>The DEEP site sediment sequence obtained during the ICDP SCOPSCO project at Lake Ohrid was dated using tephrostratigraphic information, cyclostratigraphy, and orbital tuning through the marine isotope stages (<span class="hlt">MIS</span>) 15-1. Although this approach is suitable for the generation of a general chronological framework of the long succession, it is insufficient to resolve more detailed palaeoclimatological questions, such as leads and lags of climate events between marine and terrestrial records or between different regions. Here, we demonstrate how the use of different tie points can affect cyclostratigraphy and orbital tuning for the period between ca. 140 and 70 ka and how the results can be correlated with directly/indirectly radiometrically dated Mediterranean marine and continental proxy records. The alternative age model presented here shows consistent differences with that initially proposed by Francke et al. (2015) for the same interval, in particular at the level of the <span class="hlt">MIS</span>6-5e transition. According to this new age model, different proxies from the DEEP site sediment record support an increase of temperatures between glacial to interglacial conditions, which is almost synchronous with a rapid increase in sea surface temperature observed in the western Mediterranean. The results show how a detailed study of independent chronological tie points is important to align different records and to highlight asynchronisms of climate events. Moreover, Francke et al. (2016) have incorporated the new chronology proposed for tephra OH-DP-0499 in the final DEEP age model. This has reduced substantially the chronological discrepancies between the DEEP site age model and the model proposed here for the last glacial-interglacial transition.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMOS21A1974C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMOS21A1974C"><span>Constraining Seasonal and Vertical Distributions of Planktonic Foraminifera for Paleoclimate Reconstruction Since <span class="hlt">MIS</span>3 at the Axial Seamount, Juan de Fuca Ridge</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Chen, S. L.; Ravelo, A. C.; Clague, D. A.</p> <p>2015-12-01</p> <p>The California Current is an upwelling region with dynamic interactions between circulation, biological productivity and ecology. A 77 cm piston push core was taken from the Juan de Fuca Ridge Axial Seamount using a Remotely Operated Vehicle (ROV) (2213m, 45.55º N, 130.08º W), an active submarine volcano ~480 km off Oregon's coast. Five radiocarbon dates indicate that the sediment ranges from 42.6 ka at 77 cm to 17.6 ka at 15 cm, with an average sediment accumulation rate of 2.47 cm/ka from 77-15 cm, and an average rate of 0.85 cm/ka during the postglacial period (<17.6 ka). Multiple species of planktic foraminifera from the core representing subtropical, subartic, and arctic fauna have been used to constrain changes in vertical and seasonal temperature since Marine Isotope Stage 3 (<span class="hlt">MIS</span>3). Measurements of δ18O of the upwelling species Globigerina bulloides, the thermocline dwelling species Neogloboquadrina dutertrei, and the warm mixed-layer species Orbulina universa are offset from each other, reflecting vertical and seasonal variation among the planktonic foraminifera. Of the three species, G. bulloides shows the least variation in δ18O, possibly indicating that marked changes in temperature are masking changes in the δ18O of seawater due to global ice volume changes. G. bulloides and O. universa δ18O values are similar in <span class="hlt">MIS</span> 3 and diverge with time, indicating the development of strong seasonal succession of species, since the last glacial maximum. Bulk nitrogen isotopes and nitrogen flux provide additional constraints on upwelling strength and insight into local biological productivity and nutrient dynamics. Obtaining Mg/Ca data will clarify the δ 18O interpretation except deep in the core where metal-bearing authigenic precipitates affect Mg concentrations. These climatic proxies together provide insight into how global climate change and local seamount volcanism impacts regional productivity in the California Current.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016ApPhA.122..519R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016ApPhA.122..519R"><span>Electrical properties and transport mechanisms of Au/Ba0.6Sr0.4TiO3/GaN metal-insulator-semiconductor (<span class="hlt">MIS</span>) diode at high temperature range</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rajagopal Reddy, V.</p> <p>2016-05-01</p> <p>The electrical and transport mechanisms of a fabricated Au/Ba0.6Sr0.4TiO3 (BST)/GaN metal-insulator-semiconductor (<span class="hlt">MIS</span>) diode have been studied in the temperature range of 280-430 K by current-voltage ( I- V) and capacitance-voltage ( C- V) measurements. The barrier heights (BHs) of the Au/BST/GaN <span class="hlt">MIS</span> diode are found to be 0.85 eV ( I- V)/1.35 ( C- V) at 280 K and 1.14 eV ( I- V)/1.17 ( C- V) at 430 K. The series resistance ( R S) values determined by Cheung's functions are in good agreement with each other. The difference between BHs estimated by I- V and C- V methods are also discussed. Results show that the estimated interface state density ( N SS) of <span class="hlt">MIS</span> diode decreases with an increase in temperature. Observations have indicated that the BH increases whereas ideality factor R S and N SS decreases with increasing temperature. Results have demonstrated that the reverse leakage current is dominated by Poole-Frenkel emission at temperatures of 280-340 K and by Schottky emission at temperatures of 370-430 K. It is also noted that there is a transition of the conduction mechanism in Au/BST/GaN <span class="hlt">MIS</span> diode from Poole-Frenkel to Schottky emission at temperatures of 340-370 K.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA084132','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA084132"><span><span class="hlt">Vib</span>-Rotational Energy Transfer and Relaxation Patterns in Non-Equilibrium Chemical Systems.</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1980-03-01</p> <p>Officer Director, Aeronautical Systems FOR THE COMMANDER GORDON L. HERMANN Lt Colonel, USAF Executive Officer Aocession For NTIS G., DX TAB Unar .un o...the appropriate thermodynamic potential which, in the case of a closed system coupled to a heat bath, is the Helmholtz free energy. We add that if one</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=coast&pg=2&id=EJ764717','ERIC'); return false;" href="http://eric.ed.gov/?q=coast&pg=2&id=EJ764717"><span>Awakening to Opportunities in International Business: A Title <span class="hlt">VI-B</span> Grant and Partnership Approach</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Haynes, Joan; Rutz, Rebecca</p> <p>2007-01-01</p> <p>Subsequent to hurricane Katrina, Mississippi Gulf Coast businesses are rebuilding and rewriting rules. This catastrophic event has offered the coast a tremendous opportunity to write new rules furthering the redevelopment and expansion of international trade through the ports of Gulfport and Pascagoula and the expansion of the tourism industry.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED121045.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED121045.pdf"><span>Effects of Music Therapy on Handicapped Students: A Title <span class="hlt">VI-B</span> Project.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>McCarthy, Robert E.; Bakaitis, Patricia</p> <p></p> <p>Evaluated were the effects of music therapy sessions on the behavior of approximately 300 moderately retarded, physically handicapped and multiply handicapped students. Data on attentive behavior and disruptive behavior were recorded by 37 special education teachers, 25 instructional aides and one principal who were trained to observe and record…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010cosp...38.3071B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010cosp...38.3071B"><span>The ESA Mice in Space (<span class="hlt">MIS</span>) habitat: effects of cage confinement on neuromusculoskeletal structure and function and stress/behavior using wild-type C57Bl/6JRj mice in a modular science reference model (MSRM) test on ground</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Blottner, Dieter; Vico, Laurence; Jamon, D. Berckmansp L. Vicop Y. Liup R. Canceddap M.</p> <p></p> <p>Background: Environmental conditions likely affect physiology and behaviour of mice used for Life Sciences Research on Earth and in Space. Thus, mice habitats with sufficient statistical numbers should be developed for adequate life support and care and that should meet all nesces-sary ethical and scientific requirements needed to successfully perform animal experimentation in Space. Aim of study: We here analysed the effects of cage confinement on the weightbear-ing musculoskeletal system, behaviour and stress of wild-type mice (C57BL/6JRj, 30 g b.wt., total n = 24) housed for 25 days in a prototypical ground-based MSRM (modular science ref-erence module) in the frame of breadboard activities for a fully automated life support habitat called "Mice in Space" (<span class="hlt">MIS</span>) at the Leuven University, Belgium. Results: Compared with control housing (individually ventilated cages, IVC-mice) the <span class="hlt">MIS</span> mice revealed no significant changes in soleus muscle size and myofiber distribution (type I vs. II) and quality of bone (3-D microarchitecture and mineralisation of calvaria, spine and femur) determined by confocal and micro-computed tomography. Corticosterone metabolism measured non-invasively (faeces) monitored elevated adrenocortical activity at only start of the <span class="hlt">MIS</span> cage confinement (day 1). Behavioural tests (i.e., grip strength, rotarod, L/D box, elevated plus-maze, open field, ag-gressiveness) performed subsequently revealed only minor changes in motor performance (<span class="hlt">MIS</span> vs. controls). Conclusions: The <span class="hlt">MIS</span> habitat will not, on its own, produce major effects that could confound interpretation of data induced by microgravity exposure on orbit as planned for future biosatellite programmes. Sponsors: ESA-ESTEC, Noordwijk, NL</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013EGUGA..15.7271M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013EGUGA..15.7271M"><span>Millennial scale precipitation changes over Easter Island (Southern Pacific) during <span class="hlt">MIS</span> 3: Inter-hemispheric connections during North Atlantic abrupt cold events</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Margalef, Olga; Cacho, Isabel; Pla-Rabes, Sergi; Cañellas-Boltà, Núria; Pueyo, Juan Jose; Sáez, Alberto; Valero-Garcés, Blas L.; Giralt, Santiago</p> <p>2013-04-01</p> <p>Marine Isotope Stage (<span class="hlt">MIS</span>) 3 climate has been globally characterized by the occurrence of millennial-scale climate variations defined over North Atlantic as Dansgaard-Oeschger and Heinrich events. Despite climate variability has been broadly explored over North Atlantic records, the response of the tropical and subtropical latitudes, especially in the Southern Hemisphere, still remains as a matter of debate. Rano Aroi peat record (Easter Island, Chile, 27°S) provides a unique opportunity to understand Southern Pacific atmospheric and oceanic changes during these stadial-interstadial transitions because of its exceptional location on the interplay of the South Pacific Convergence Zone (SPCZ), the Intertropical Convergence Zone (ITCZ), the South Pacific Anticyclone (SPA) and the Southern Westerlies (SW). Rano Aroi record contains 8 main enhanced precipitation events between 70 and 40 kyr BP that can be correlated with the timing of Heinrich events 5, 5a and 6 as well as other cold stadials. These humid events are also present in other Southern Hemisphere continental sites and correspond to dry periods on Northern Hemisphere records. This opposite hydrologic trend has been explained by the latitudinal migration of ITCZ and has been supported by several climatic models. As Easter Island precipitation is mainly dependent on SPCZ storm track belt activity, we suggest that the southern migration of the ITCZ is associated to an expansion of SPCZ to the east. This process should be intimately related to a weakening of the Walker circulation, which is further supported by an estimation of d18Osw gradient along the equator for the same time period. Consequently, atmospheric and oceanic responses during these cold stadials and Heinrich events might lead to a configuration that resembles the warm ENSO state over Southern Pacific, as previously suggested by some global climatic models. Rano Aroi record clearly points out that shifts in hydrological cycle in tropical Southern</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1208669-modifications-toxic-cug-rnas-induce-structural-stability-rescue-mis-splicing-myotonic-dystrophy-cell-model-reduce-toxicity-myotonic-dystrophy-zebrafish-model','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1208669-modifications-toxic-cug-rnas-induce-structural-stability-rescue-mis-splicing-myotonic-dystrophy-cell-model-reduce-toxicity-myotonic-dystrophy-zebrafish-model"><span>Modifications to toxic CUG RNAs induce structural stability, rescue <span class="hlt">mis</span>-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model</span></a></p> <p><a target="_blank" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>deLorimier, Elaine; Coonrod, Leslie A.; Copperman, Jeremy; ...</p> <p>2014-10-10</p> <p>In this study, CUG repeat expansions in the 3' UTR of dystrophia myotonica protein kinase (DMPK) cause myotonic dystrophy type 1 (DM1). As RNA, these repeats elicit toxicity by sequestering splicing proteins, such as MBNL1, into protein–RNA aggregates. Structural studies demonstrate that CUG repeats can form A-form helices, suggesting that repeat secondary structure could be important in pathogenicity. To evaluate this hypothesis, we utilized structure-stabilizing RNA modifications pseudouridine (Ψ) and 2'-O-methylation to determine if stabilization of CUG helical conformations affected toxicity. CUG repeats modified with Ψ or 2'-O-methyl groups exhibited enhanced structural stability and reduced affinity for MBNL1. Molecular dynamicsmore » and X-ray crystallography suggest a potential water-bridging mechanism for Ψ-mediated CUG repeat stabilization. Ψ modification of CUG repeats rescued <span class="hlt">mis</span>-splicing in a DM1 cell model and prevented CUG repeat toxicity in zebrafish embryos. This study indicates that the structure of toxic RNAs has a significant role in controlling the onset of neuromuscular diseases.« less</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/1208669','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/1208669"><span>Modifications to toxic CUG RNAs induce structural stability, rescue <span class="hlt">mis</span>-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>deLorimier, Elaine; Coonrod, Leslie A.; Copperman, Jeremy; Taber, Alex; Reister, Emily E.; Sharma, Kush; Todd, Peter K.; Guenza, Marina G.; Berglund, J. Andrew</p> <p>2014-10-10</p> <p>In this study, CUG repeat expansions in the 3' UTR of dystrophia myotonica protein kinase (<i>DMPK</i>) cause myotonic dystrophy type 1 (DM1). As RNA, these repeats elicit toxicity by sequestering splicing proteins, such as MBNL1, into protein–RNA aggregates. Structural studies demonstrate that CUG repeats can form A-form helices, suggesting that repeat secondary structure could be important in pathogenicity. To evaluate this hypothesis, we utilized structure-stabilizing RNA modifications pseudouridine (Ψ) and 2'-O-methylation to determine if stabilization of CUG helical conformations affected toxicity. CUG repeats modified with Ψ or 2'-O-methyl groups exhibited enhanced structural stability and reduced affinity for MBNL1. Molecular dynamics and X-ray crystallography suggest a potential water-bridging mechanism for Ψ-mediated CUG repeat stabilization. Ψ modification of CUG repeats rescued <span class="hlt">mis</span>-splicing in a DM1 cell model and prevented CUG repeat toxicity in zebrafish embryos. This study indicates that the structure of toxic RNAs has a significant role in controlling the onset of neuromuscular diseases.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017SSEle.129..206C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017SSEle.129..206C"><span>In0.18Al0.82N/AlN/GaN <span class="hlt">MIS</span>-HEMT on Si with Schottky-drain contact</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Chen, P.-G.; Tang, M.; Liao, M.-H.; Lee, M. H.</p> <p>2017-03-01</p> <p>Indium-based ternary-barrier high-electron-mobility transistors (HEMT) directly on Si substrate are demonstrated in this work, using a structure of In0.18Al0.82N/AlN/GaN-on-Si for high-power applications. The advantages of HEMTs on Si substrates are the low cost and high throughput, which are beneficial for large wafer scale. The thermal dissipation of Si occurs between SiC and the sapphire substrate. The proposed InAlN-barrier HEMTs exhibit a high ON/OFF ratio with >7 orders of magnitudes and an excellent subthreshold swing (SS) below 100 mV/dec, owing to high polarization and less lattice mismatch with GaN. The IDsat is measured to be 163 mA/mm at VDS = 10 V and VG = 2 V with LG = 2 μm. When compared with the control InAlN/AlN/GaN-on-Si <span class="hlt">MIS</span>-HEMTs with Ohmic contacts, the OFF current is reduced by one order magnitude when using the Schottky-drain contact technology.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2792709','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2792709"><span><span class="hlt">Mis</span>-Spliced Transcripts of Nicotinic Acetylcholine Receptor α6 Are Associated with Field Evolved Spinosad Resistance in Plutella xylostella (L.)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Baxter, Simon W.; Chen, Mao; Dawson, Anna; Zhao, Jian-Zhou; Vogel, Heiko; Shelton, Anthony M.; Heckel, David G.; Jiggins, Chris D.</p> <p>2010-01-01</p> <p>The evolution of insecticide resistance is a global constraint to agricultural production. Spinosad is a new, low-environmental-risk insecticide that primarily targets nicotinic acetylcholine receptors (nAChR) and is effective against a wide range of pest species. However, after only a few years of application, field evolved resistance emerged in the diamondback moth, Plutella xylostella, an important pest of brassica crops worldwide. Spinosad resistance in a Hawaiian population results from a single incompletely recessive and autosomal gene, and here we use AFLP linkage mapping to identify the chromosome controlling resistance in a backcross family. Recombinational mapping with more than 700 backcross progeny positioned a putative spinosad target, nAChR alpha 6 (Pxα6), at the resistance locus, PxSpinR. A mutation within the ninth intron splice junction of Pxα6 results in <span class="hlt">mis</span>-splicing of transcripts, which produce a predicted protein truncated between the third and fourth transmembrane domains. Additional resistance-associated Pxα6 transcripts that excluded the mutation containing exon were detected, and these were also predicted to produce truncated proteins. Identification of the locus of resistance in this important crop pest will facilitate field monitoring of the spread of resistance and offer insights into the genetic basis of spinosad resistance in other species. PMID:20062520</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013MatSP..31..446K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013MatSP..31..446K"><span>Analysis of <span class="hlt">MIS</span> equivalent electrical circuit of Au/Pd/Ti-SiO2-GaAs structure based on DLTS measurements</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kochowski, S.; Drewniak, Ł.; Nitsch, K.; Paszkiewicz, R.; Paszkiewicz, B.</p> <p>2013-08-01</p> <p>In this paper <span class="hlt">MIS</span> equivalent electrical circuit of Au/Pd/Ti-SiO2-GaAs has been analyzed by a comparison of the results obtained from admittance and DLTS spectroscopy. Two groups of peaks with different magnitude and different gate voltage dependence have been observed in DLTS and admittance spectra. Based on the analysis of the peaks behavior, it has been concluded that they are associated with the response of bulk traps and interface states, respectively. In order to characterize bulk traps and interface states responsible for the occurrence of two groups of peaks in normalized conductance spectra we have used the equivalent circuit with two CPE-R branches. The time constant values estimated for both peaks from admittance analysis have been compared with the time constant determined from DLTS analysis. Some discrepancies have been noted between the time constants obtained for interface states whereas the time constants for bulk traps were compatible. It has been also demonstrated that when conductance peaks overlap, the admittance experimental data can be fitted by the equivalent electrical model with only one CPE-R branch. However, in this case incomplete information about the analyzed process has been obtained despite the fact that all model validity criteria can be fulfilled and the model seems to be correct.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016NatSR...632365L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016NatSR...632365L"><span>Rapid and cyclic dust accumulation during <span class="hlt">MIS</span> 2 in Central Asia inferred from loess OSL dating and grain-size analysis</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Li, Yun; Song, Yougui; Lai, Zhongping; Han, Li; An, Zhisheng</p> <p>2016-09-01</p> <p>Due to lack of reliable proxies from the Westerlies-dominant region, the strength change of Northern Hemisphere Westerlies remains poorly understood. The aim of this study is to provide a reliable paleoclimatic proxy about the Northern Hemisphere Westerlies change. Here we report a 30.7 m thick loess section from the Ili basin directly controlled by the Westerlies. Based on optically stimulated luminescence (OSL) and high resolution grain-size records, we reconstruct the change history of the Westerlies strength during the last glacial period (mainly Marine Isotope Stages 2, <span class="hlt">MIS</span>2), being similar with the Westerlies index recorded in the Qinghai Lake sediments. Within error limits, all ages are in stratigraphic order. We further compare the climatic records among the Ili loess, Qinghai Lake and the NGRIP, their similarity shows a good climatic coupling relationship among the Central Asia, East Asia and the North Atlantic, and the Westerlies plays a critical influence in transporting the North Atlantic signal to Central and East Asia.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27586593','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27586593"><span>Rapid and cyclic dust accumulation during <span class="hlt">MIS</span> 2 in Central Asia inferred from loess OSL dating and grain-size analysis.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Yun; Song, Yougui; Lai, Zhongping; Han, Li; An, Zhisheng</p> <p>2016-09-02</p> <p>Due to lack of reliable proxies from the Westerlies-dominant region, the strength change of Northern Hemisphere Westerlies remains poorly understood. The aim of this study is to provide a reliable paleoclimatic proxy about the Northern Hemisphere Westerlies change. Here we report a 30.7 m thick loess section from the Ili basin directly controlled by the Westerlies. Based on optically stimulated luminescence (OSL) and high resolution grain-size records, we reconstruct the change history of the Westerlies strength during the last glacial period (mainly Marine Isotope Stages 2, <span class="hlt">MIS</span>2), being similar with the Westerlies index recorded in the Qinghai Lake sediments. Within error limits, all ages are in stratigraphic order. We further compare the climatic records among the Ili loess, Qinghai Lake and the NGRIP, their similarity shows a good climatic coupling relationship among the Central Asia, East Asia and the North Atlantic, and the Westerlies plays a critical influence in transporting the North Atlantic signal to Central and East Asia.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21152341','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21152341"><span>Is Social Phobia a "<span class="hlt">Mis</span>-Communication" Disorder? Brain Functional Connectivity during Face Perception Differs between Patients with Social Phobia and Healthy Control Subjects.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Danti, Sabrina; Ricciardi, Emiliano; Gentili, Claudio; Gobbini, Maria Ida; Pietrini, Pietro; Guazzelli, Mario</p> <p>2010-01-01</p> <p>Recently, a differential recruitment of brain areas throughout the distributed neural system for face perception has been found in social phobic patients as compared to healthy control subjects. These functional abnormalities in social phobic patients extend beyond emotion-related brain areas, such as the amygdala, to include cortical networks that modulate attention and process other facial features, and they are also associated with an alteration of the task-related activation/deactivation trade-off. Functional connectivity is becoming a powerful tool to examine how components of large-scale distributed neural systems are coupled together while performing a specific function. This study was designed to determine whether functional connectivity networks among brain regions within the distributed system for face perception also would differ between social phobic patients and healthy controls. Data were obtained from eight social phobic patients and seven healthy controls by using functional magnetic resonance imaging. Our findings indicated that social phobic patients and healthy controls have different patterns of functional connectivity across brain regions within both the core and the extended systems for face perception and the default mode network. To our knowledge, this is the first study that shows that functional connectivity during brain response to socially relevant stimuli differs between social phobic patients and healthy controls. These results expand our previous findings and indicate that brain functional changes in social phobic patients are not restricted to a single specific brain structure, but rather involve a <span class="hlt">mis</span>-communication among different sensory and emotional processing brain areas.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011QSRv...30.2107Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011QSRv...30.2107Z"><span>Late-Pleistocene (<span class="hlt">MIS</span> 3-2) palaeoenvironments as recorded by sediments, palaeosols, and ground-squirrel nests at Duvanny Yar, Kolyma lowland, northeast Siberia</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zanina, O. G.; Gubin, S. V.; Kuzmina, S. A.; Maximovich, S. V.; Lopatina, D. A.</p> <p>2011-08-01</p> <p>A detailed study of the Duvanny Yar section in the Kolyma Lowland (Yakutia) provides the most extensive knowledge to date about late-Pleistocene soil formation processes and environments in the North-East Siberian Arctic. Late-Quaternary palaeoenvironmental changes were reconstructed using paleopedological data and a range of palaeoecological bio-indicators (palynomorphs, plant macrofossils and insects). The frozen sediments representing marine isotope stage 3 (<span class="hlt">MIS</span>-3), which encompasses the Karginsky interstadial, include profiles of four palaeosols of different ages. The oldest palaeosol is early Karginskian, and three overlying soil horizons represent a late-Karginskian pedocomplex. Palaeopedological data indicate a change of from synlithogenic soil formation processes to epigenic ones during these intervals. The intervening periods of synlithogenic pedogenesis were accompanied by active accumulation of eolian deposits. The Earlier Karginskian period of pedogenesis occurred in the absence of eolian sedimentation and when summer conditions were warm. The wide spectrum of peaty and peaty-gley soils observed in the late-Karginskian deposits developed under conditions of progressive cooling. The structure and content of fossil rodent burrows dated to approximately 30 000 yr BP from frozen late-Pleistocene deposits at Duvanny Yar indicate an arid and severe climate, a depth of active layer of 60-80 cm, and a wide distribution of disturbed habitats with pioneer and steppe vegetation.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_13");'>13</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li class="active"><span>15</span></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_15 --> <div id="page_16" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="301"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016SSEle.124...54Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016SSEle.124...54Y"><span>TMAH-based wet surface pre-treatment for reduction of leakage current in AlGaN/GaN <span class="hlt">MIS</span>-HEMTs</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yoon, Young Jun; Seo, Jae Hwa; Cho, Min Su; Kang, Hee-Sung; Won, Chul-Ho; Kang, In Man; Lee, Jung-Hee</p> <p>2016-10-01</p> <p>The pre-passivation surface treatment process with tetramethylammonium hydroxide (TMAH)-based wet solution was proposed for the minimization of the leakage current (Ileak) in AlGaN/GaN metal-insulator-semiconductor high electron mobility transistors (<span class="hlt">MIS</span>-HEMTs). This process step contributes to the simultaneous decrease of the surface current (Isurf) in the active region of device and mesa-isolated region by removing the surface states and traps related to nitrogen (N) vacancy, Ga-oxide, and dangling bonds. Using the surface treatment, the fabricated device achieves a lower off-state current (Ioff) of ∼10-12 A/mm, a higher on/off current ratio (Ion/Ioff) of ∼1011, a small subthreshold swing (SS) of 68.4 mV/dec. The reduced Ileak also improves breakdown voltage (BV). In addition, the interface trap density (Dit) between the SiN layer and the AlGaN surface was extracted to evaluate the quality of the SiN/GaN interface, which showed that the treatment decreases the Dit with reduction of the surface defects.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5009356','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5009356"><span>Rapid and cyclic dust accumulation during <span class="hlt">MIS</span> 2 in Central Asia inferred from loess OSL dating and grain-size analysis</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Li, Yun; Song, Yougui; Lai, Zhongping; Han, Li; An, Zhisheng</p> <p>2016-01-01</p> <p>Due to lack of reliable proxies from the Westerlies-dominant region, the strength change of Northern Hemisphere Westerlies remains poorly understood. The aim of this study is to provide a reliable paleoclimatic proxy about the Northern Hemisphere Westerlies change. Here we report a 30.7 m thick loess section from the Ili basin directly controlled by the Westerlies. Based on optically stimulated luminescence (OSL) and high resolution grain-size records, we reconstruct the change history of the Westerlies strength during the last glacial period (mainly Marine Isotope Stages 2, <span class="hlt">MIS</span>2), being similar with the Westerlies index recorded in the Qinghai Lake sediments. Within error limits, all ages are in stratigraphic order. We further compare the climatic records among the Ili loess, Qinghai Lake and the NGRIP, their similarity shows a good climatic coupling relationship among the Central Asia, East Asia and the North Atlantic, and the Westerlies plays a critical influence in transporting the North Atlantic signal to Central and East Asia. PMID:27586593</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/459943','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/459943"><span>Wet oxidation of Al{sub x}GA{sub 1-x}As: arsenic barriers on the road to <span class="hlt">mis</span></span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ashby, C.I.H.; Sullivan, J.P.; Newcomer, P.P.; Missert, N.A.; Hou, H.Q.; Hammons, B.E.; Baca, A.G.</p> <p>1997-02-01</p> <p>Three characteristic regimes were identified during wet thermal oxidation of AlxGa(1-x)As (x=1 to 0.90) on GaAs: oxidation of Al and Ga in the alloy to form to an amorphous oxide layer, formation and elimination of elemental As and of amorphous As2O3, and crystallization of the oxide film. Residual As can produce up to a 100fold increase in leakage current and a 30% increase in bulk dielectric constant. Very low As levels produce partial Fermi-level pinning at the oxidized AlxGa(1-x)As/GaAs interface. Local Schottky- barrier pinning of the Fermi level at As precipitates at the oxide/GaAs interface may be the source of the apparent high interface state density. The presence of thermodynamically favored interfacial As may impose a fundamental limit on the application of AlGaAs wet oxidation for achieving <span class="hlt">MIS</span> devices without post-oxidation processing to remove the residual As from the interface.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009AGUFMPP43A1564P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009AGUFMPP43A1564P"><span>Constraints on Neogene deformation in the southern Terror Rift from calcite twinning analyses of veins within the ANDRILL <span class="hlt">MIS</span> core, Victoria Land Basin, Antarctica</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Paulsen, T. S.; Demosthenous, C.; Wilson, T. J.; Millan, C.</p> <p>2009-12-01</p> <p>The ANDRILL <span class="hlt">MIS</span> (McMurdo Ice Shelf) Drilling Project obtained over 1200 meters of Neogene sedimentary and volcanic rocks in 2006/2007. Systematic fracture logging of the AND-1B core identified 1,475 natural fractures, i.e. pre-existing fractures in the rock intersected by coring. The most abundant natural fractures are normal faults and calcite veins; reverse faults, brecciated zones, and sedimentary intrusions are also present. In order to better understand Neogene deformation patterns within the southern Terror Rift, we have been conducting strain analyses on mechanically twinned calcite within healed fractures in the drill core. Twinning strains using all of the data from each sample studied to date range from 2% to 10%. The cleaned data (20% of the largest magnitude deviations removed) typically show ≤30% negative expected values, consistent with a single deformation episode or multiple ~coaxial deformation episodes. The majority of the samples record horizontal extension, similar to strain patterns expected in a normal fault regime and/or vertical sedimentary compaction in a continental rift system. The morphology, width, and intensity of twins in the samples suggest that twinning typically occurred at temperatures <170° C. Twinning intensities suggest differential stress magnitudes that caused the twinning ranged from 216 to 295 MPa.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014RuPhJ..57..633V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014RuPhJ..57..633V"><span>Special Features of Admittance in <span class="hlt">Mis</span> Structures Based on Graded-Gap MBE n-Hg1- x Cd x Te ( x = 0.31-0.32) in a Temperature Range OF 8-300 K</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Voitsekhovskii, A. V.; Nesmelov, S. N.; Dzyadukh, S. M.; Vasil'ev, V. V.; Varavin, V. S.; Dvoretskii, S. A.; Mikhailov, N. N.; Kuz'min, V. D.; Remesnik, V. G.</p> <p>2014-09-01</p> <p>Admittance of <span class="hlt">MIS</span> structures based on graded-gap n-Hg1- х Cd х Te ( x = 0.31-0.32) grown by molecular beam epitaxy (MBE) is investigated in a wide temperature range (8-300 K). It is shown that the temperature and frequency dependences of the differential resistance of space charge region for structures with a graded-gap layer are qualitatively similar to those for structures without a graded-gap layer. It is found that for <span class="hlt">MIS</span> structures based on MBE n-Hg1- х Cd х Te ( x = 0.31-0.32), regardless of the presence of a graded-gap layer, the differential resistance of space charge region is limited by the processes of Shockley-Read generation in the temperature range of 25-100 K.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMPP21A1282V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMPP21A1282V"><span>Marine Isotope Stage (<span class="hlt">MIS</span>) 5 on the Umnak Plateau, Bering Sea (IODP Site U1339): Using diatom taxonomy, grain size and nitrogen isotopic composition of marine sediments as proxies for primary productivity and sea ice extent</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Vaughn, D.; Caissie, B.</p> <p>2014-12-01</p> <p>The current rapid reduction of sea ice in the Arctic has motivated numerous studies to look at how sea ice declines during times of climate warming and its impact on marine ecosystems. Marine Isotope Stage (<span class="hlt">MIS</span>) 5 is the last interglacial prior to the Holocene and has been characterized as having higher summer air temperatures and higher sea level compared to today. However, there is a scarcity of data for sea ice extent during <span class="hlt">MIS</span> 5. This presents an opportunity to reconstruct sea ice during a previous warming that may be used as an analogue for future change. We aim to provide insight into how sea ice changed throughout <span class="hlt">MIS</span> 5 and how this change impacted primary productivity at the Umnak Plateau in the southeastern Bering Sea. This region is not currently covered by sea ice at all; however, low-resolution work reveals that sea ice did reach the study area during glacial intervals. This study uses high-resolution (500 year) bulk geochemistry, diatom taxonomy, and grain size analysis of marine sediments from the Umnak Plateau as proxies for primary production and sea ice conditions during <span class="hlt">MIS</span> 5. Nitrogen isotopic measurements of marine sediments are a valuable recorder of nitrate utilization by primary producers. Diatom taxonomy gives corresponding ecological affinities, which are relatable to sea ice coverage, productivity, and sea surface temperatures. Grain size analyses from previous studies have shown clay- and silt-sized biogenic content with well-preserved diatom valves to be associated with interglacials and larger silt to sand-size siliclastic particles with fragmented diatom valves to be associated with glacials. In this study, the silt fraction appears to be constant while the clay fraction follows the oxygen isotope record from Lisiecki and Raymo, 2005, increasing during glacial intervals and stadials. This apparent contradiction with earlier work warrants further investigation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016RuPhJ..59..920V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016RuPhJ..59..920V"><span>Temperature and Field Dependences of Parameters of the Equivalent Circuit Elements of <span class="hlt">MIS</span> Structures Based on MBE n-Hg0.775Cd0.225Te in the Strong Inversion Mode</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Voitsekhovskii, A. V.; Nesmelov, S. N.; Dzyadukh, S. M.</p> <p>2016-11-01</p> <p>A technique is proposed for the determining the parameters of the equivalent circuit elements in strong inversion mode using the measurement results of the admittance of <span class="hlt">MIS</span> structures based on n-Hg0.775Cd0.225Te grown by molecular beam epitaxy. It is shown that at 77 K and frequencies above 10 kHz, the capacitancevoltage characteristics of <span class="hlt">MIS</span> structures based on n-Hg0.775Cd0.225Te with a near-surface graded gap layer have a high-frequency behavior with respect to the recharge time of surface states located near the Fermi level of intrinsic semiconductor. It is established that the electron concentration in the near-surface graded-gap layer exceeds an average concentration found by the Hall method by more than 2 times. The proposed technique was used for determining the temperature dependences of the insulator capacitance, capacitance and differential resistance of the space-charge region, and capacitance of the inversion layer in <span class="hlt">MIS</span> structures based on n-Hg0.775Cd0.225Te without a graded-gap layer. The temperature and voltage dependences of the parameters of the equivalent circuit elements in strong inversion are calculated. The results of calculation are qualitatively consistent with the results obtained from the measurements of the admittance.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014QuRes..82..618M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014QuRes..82..618M"><span>Summary of the Snowmastodon Project Special Volume. A high-elevation, multi-proxy biotic and environmental record of <span class="hlt">MIS</span> 6-4 from the Ziegler Reservoir fossil site, Snowmass Village, Colorado, USA</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Miller, Ian M.; Pigati, Jeffrey S.; Scott Anderson, R.; Johnson, Kirk R.; Mahan, Shannon A.; Ager, Thomas A.; Baker, Richard G.; Blaauw, Maarten; Bright, Jordon; Brown, Peter M.; Bryant, Bruce; Calamari, Zachary T.; Carrara, Paul E.; Cherney, Michael D.; Demboski, John R.; Elias, Scott A.; Fisher, Daniel C.; Gray, Harrison J.; Haskett, Danielle R.; Honke, Jeffrey S.; Jackson, Stephen T.; Jiménez-Moreno, Gonzalo; Kline, Douglas; Leonard, Eric M.; Lifton, Nathaniel A.; Lucking, Carol; Gregory McDonald, H.; Miller, Dane M.; Muhs, Daniel R.; Nash, Stephen E.; Newton, Cody; Paces, James B.; Petrie, Lesley; Plummer, Mitchell A.; Porinchu, David F.; Rountrey, Adam N.; Scott, Eric; Sertich, Joseph J. W.; Sharpe, Saxon E.; Skipp, Gary L.; Strickland, Laura E.; Stucky, Richard K.; Thompson, Robert S.; Wilson, Jim</p> <p>2014-11-01</p> <p>In North America, terrestrial records of biodiversity and climate change that span Marine Oxygen Isotope Stage (<span class="hlt">MIS</span>) 5 are rare. Where found, they provide insight into how the coupling of the ocean-atmosphere system is manifested in biotic and environmental records and how the biosphere responds to climate change. In 2010-2011, construction at Ziegler Reservoir near Snowmass Village, Colorado (USA) revealed a nearly continuous, lacustrine/wetland sedimentary sequence that preserved evidence of past plant communities between ~ 140 and 55 ka, including all of <span class="hlt">MIS</span> 5. At an elevation of 2705 m, the Ziegler Reservoir fossil site also contained thousands of well-preserved bones of late Pleistocene megafauna, including mastodons, mammoths, ground sloths, horses, camels, deer, bison, black bear, coyotes, and bighorn sheep. In addition, the site contained more than 26,000 bones from at least 30 species of small animals including salamanders, otters, muskrats, minks, rabbits, beavers, frogs, lizards, snakes, fish, and birds. The combination of macro- and micro-vertebrates, invertebrates, terrestrial and aquatic plant macrofossils, a detailed pollen record, and a robust, directly dated stratigraphic framework shows that high-elevation ecosystems in the Rocky Mountains of Colorado are climatically sensitive and varied dramatically throughout <span class="hlt">MIS</span> 5.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015CliPD..11.1407M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015CliPD..11.1407M"><span>Millennial-scale precipitation variability over Easter Island (South Pacific) during <span class="hlt">MIS</span> 3: inter-hemispheric teleconnections with North Atlantic abrupt cold events</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Margalef, O.; Cacho, I.; Pla-Rabes, S.; Cañellas-Boltà, N.; Pueyo, J. J.; Sáez, A.; Pena, L. D.; Valero-Garcés, B. L.; Rull, V.; Giralt, S.</p> <p>2015-04-01</p> <p>Marine Isotope Stage 3 (<span class="hlt">MIS</span> 3, 59.4-27.8 kyr BP) is characterized by the occurrence of rapid millennial-scale climate oscillations known as Dansgaard-Oeschger cycles (DO) and by abrupt cooling events in the North Atlantic known as Heinrich events. Although both the timing and dynamics of these events have been broadly explored in North Atlantic records, the response of the tropical and subtropical latitudes to these rapid climatic excursions, particularly in the Southern Hemisphere, still remains unclear. The Rano Aroi peat record (Easter Island, 27° S) provides a unique opportunity to understand atmospheric and oceanic changes in the South Pacific during these DO cycles because of its singular location, which is influenced by the South Pacific Anticyclone (SPA), the Southern Westerlies (SW), and the Intertropical Convergence Zone (ITCZ) linked to the South Pacific Convergence Zone (SPCZ). The Rano Aroi sequence records 6 major events of enhanced precipitation between 38 and 65 kyr BP. These events are compared with other hydrological records from the tropical and subtropical band supporting a coherent regional picture, with the dominance of humid conditions in Southern Hemisphere tropical band during Heinrich Stadials (HS) 5, 5a and 6 and other Stadials while dry conditions prevailed in the Northern tropics. This antiphased hydrological pattern between hemispheres has been attributed to ITCZ migration, which in turn might be associated with an eastward expansion of the SPCZ storm track, leading to an increased intensity of cyclogenic storms reaching Easter Island. Low Pacific Sea Surface Temperature (SST) gradients across the Equator were coincident with the here-defined Rano Aroi humid events and consistent with a reorganization of Southern Pacific atmospheric and oceanic circulation also at higher latitudes during Heinrich and Dansgaard-Oeschger stadials.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016BGeo...13.3147C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016BGeo...13.3147C"><span>Ecosystem regimes and responses in a coupled ancient lake system from <span class="hlt">MIS</span> 5b to present: the diatom record of lakes Ohrid and Prespa</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cvetkoska, Aleksandra; Jovanovska, Elena; Francke, Alexander; Tofilovska, Slavica; Vogel, Hendrik; Levkov, Zlatko; Donders, Timme H.; Wagner, Bernd; Wagner-Cremer, Friederike</p> <p>2016-05-01</p> <p>We reconstruct the aquatic ecosystem interactions since the last interglacial period in the oldest, most diverse, hydrologically connected European lake system, by using palaeolimnological diatom and selected geochemistry data from Lake Ohrid "DEEP site" core and equivalent data from Lake Prespa core, Co1215. Driven by climate forcing, the lakes experienced two adaptive cycles during the last 92 ka: "interglacial and interstadial" and "glacial" cycle. The short-term ecosystems reorganizations, e.g. regime shifts within these cycles substantially differ between the lakes, as evident from the inferred amplitudes of variation. The deeper Lake Ohrid shifted between ultra oligo- and oligotrophic regimes in contrast to the much shallower Lake Prespa, which shifted from a deeper, (oligo-) mesotrophic to a shallower, eutrophic lake and vice versa. Due to the high level of ecosystem stability (e.g. trophic state, lake level), Lake Ohrid appears relatively resistant to external forcing, such as climate and environmental change. Recovering in a relatively short time from major climate change, Lake Prespa is a resilient ecosystem. At the DEEP site, the decoupling between the lakes' response to climate change is marked in the prolonged and gradual changes during the <span class="hlt">MIS</span> 5/4 and 2/1 transitions. These response differences and the lakes' different physical and chemical properties may limit the influence of Lake Prespa on Lake Ohrid. Regime shifts of Lake Ohrid due to potential hydrological change in Lake Prespa are not evident in the data presented here. Moreover, a complete collapse of the ecosystems functionality and loss of their diatom communities did not happen in either lake for the period presented in the study.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMPP13B2288B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMPP13B2288B"><span>Climate variability and volcanic history of the Eastern Romanian Carpathians since early <span class="hlt">MIS</span> 3 recorded in sediments from Mohoş crater</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bormann, M.; Veres, D.; Wulf, S.; Papadopoulou, M.; Panagiotopoulos, K.; Schaebitz, F.</p> <p>2015-12-01</p> <p>We present a 30m long sediment record covering the last ca. 50,000 years from the in-filled Mohoş crater (46°05' N; 25°55' E) located on Ciomadul volcano (Romania) that was retrieved in 2014. The record consists of bog and lacustrine sediments that are inter-bedded with tephra deposits. Ciomadul volcano, hosting the superimposed craters of Mohoş and Sf. Ana, is the youngest volcanic edifice in the Carpathian-Balkan region. Thus, tephra-analysis on the Mohoş sediments gives valuable insights into the volcanic history of that region, mainly arising from the younger crater of Sf Ana and several secondary domes. For investigations into the past climate history, the Mohoş sediment sequence has been analysed using a multi-proxy approach including geophysical, geochemical and sedimentological parameters. Multi-Sensor core logging and ITRAX X-ray fluorescence scanning have been performed at high-resolution, whereas grain size analysis, TOC and C/N ratios supplement the geophysical and geochemical data. Chronological control is based on radiocarbon and luminescence dating. We also present first results of the tephra-analysis on the Mohoş sediment record and their correlation to medium-distal pyroclastic deposits originating in this volcanic field. We further discuss responses of this mid-altitude site (1050 m a.s.l.) to past climate oscillations since early <span class="hlt">MIS</span> 3. To date, the Mohoş core record provides the longest time series from the Carpathian region. This study is part of the Collaborative Research Centre 806 "Our Way To Europe; Culture-Environment Interaction and Human Mobility in the Late Quaternary" (www.sfb806.de); subproject B2.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015BGD....1215051C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015BGD....1215051C"><span>Ecosystem regimes and responses in a coupled ancient lake system from <span class="hlt">MIS</span> 5b to present: the diatom record of lakes Ohrid and Prespa</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Cvetkoska, A.; Jovanovska, E.; Francke, A.; Tofilovska, S.; Vogel, H.; Levkov, Z.; Donders, T. H.; Wagner, B.; Wagner-Cremer, F.</p> <p>2015-09-01</p> <p>In order to understand the panarchy and interactions since the last interglacial period in the oldest, most diverse and hydrologically connected European lake system, we assess changes in the diatom record and selected geochemistry data from Lake Ohrid's "DEEP site" core and compare it with the diatom and multi-proxy data from Lake Prespa core Co1215. Driven by climate forcing, tephra impact and/or human influence, the lakes experienced two adaptive cycles during the last 92 ka: "interglacial and interstadial-regime" and "glacial-regime". The patterns of regime shifts appear synchronous in both lakes, while differences occur in the inferred amplitudes of the variations. The deeper Lake Ohrid shifted between ultraoligo- and oligotrophic regimes in contrast to the more shallow Lake Prespa, which shifts from (oligo-) mesotrophic to eutrophic conditions. In response to external forcing, Lake Ohrid exhibits a high capacity to buffer disturbances, whereas Lake Prespa is much more resilient and "recovers" in relatively short time. This decoupling of the response is evident during the <span class="hlt">MIS</span> 5/4 and 2/1 transitions, when Lake Ohrid displays prolonged and gradual changes. The lakes' specific differences in the response and feedback mechanisms and their different physical and chemical properties, probably confine a direct influence of Lake Prespa's shallow/eutrophic regimes over the productivity regimes of Lake Ohrid. Regime shifts of Lake Ohrid due to the hydrological connectivity with Lake Prespa are not evident in the data presented here. Moreover, complete ecological collapse did not happened in both lakes for the period presented in the study.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMPP13D..08K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMPP13D..08K"><span>Climate and Antartic Intermediate Water Covariations on Centennial-Millennial Timescales during <span class="hlt">MIS</span> 3—Constraining the Role of the "Oceanic Tunnel" in Abrupt Climate Change.</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Kleiven, H. F.; Ninnemann, U.</p> <p>2014-12-01</p> <p>The equatorward ventilation of Southern Hemisphere extratropical water masses to the low latitude thermocline has been proposed as a window through which the high latitude ocean can modulate tropical climate on anything from decadal to orbital timescales. This hypothesis is founded largely on the observation that tropical thermocline waters originate mostly in the Southern Hemisphere and that computer simulations suggest property anomalies in these source regions can advect through the intermediate ocean, "the ocean tunnel" to influence tropical SST. However, few observational records of extratropical ocean changes are available to assess their impacts on multi-decadal and longer timescales. Here we add to the observational record using new decadally resolved planktonic and benthic foraminiferal isotopic records spanning <span class="hlt">MIS</span> 3 (20-50 ka) from the Chilean slope ODP Site 1233 that is located on the northern margin of the Antarctic Circumpolar Current and its seafloor lies in the core of Antarctic Intermediate Water (AAIW). Thus the site is ideally situated to reconstruct both near surface and AAIW variability in the high southern latitudes. On centennial to millennial timescales, changes in intermediate water properties track those in the near surface albeit with a reduced amplitude—confirming the idea that changes in the extratropical ocean effect the oceanic tunnel on these timescales. The new benthic and plantic foraminiferal isotope results demonstrate that variations in intermediate ocean properties and climate of the southeast Pacific closely align with those recorded in the EPICA ice core from Dronning Maud Land. Such abrupt, synoptic scale changes in Antarctic climate and dynamics will have potentially widespread climatic and biogeochemical consequences along the downstream flowpath of AAIW. The broad coherence of the observed Antarctic signal supports the concept of hemispheric thermal asynchrony on millennial timescales, and the extension of this climate</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015QSRv..114..203D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015QSRv..114..203D"><span>Cova del Rinoceront (Castelldefels, Barcelona): a terrestrial record for the Last Interglacial period (<span class="hlt">MIS</span> 5) in the Mediterranean coast of the Iberian Peninsula</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Daura, J.; Sanz, M.; Julià, R.; García-Fernández, D.; Fornós, J. J.; Vaquero, M.; Allué, E.; López-García, J. M.; Blain, H. A.; Ortiz, J. E.; Torres, T.; Albert, R. M.; Rodríguez-Cintas, À.; Sánchez-Marco, A.; Cerdeño, E.; Skinner, A. R.; Asmeron, Y.; Polyak, V. J.; Garcés, M.; Arnold, L. J.; Demuro, M.; Pike, A. W. G.; Euba, I.; Rodríguez, R. F.; Yagüe, A. S.; Villaescusa, L.; Gómez, S.; Rubio, A.; Pedro, M.; Fullola, J. M.; Zilhão, J.</p> <p>2015-04-01</p> <p>The Cova del Rinoceront, a site in NE Iberia, contains a thick sedimentary fill preserving a faunal archive from the penultimate glacial and the the last interglacial periods. Layers I to III have been dated to between 74 and 147 ka, coinciding with <span class="hlt">MIS</span> 5a to 5e, a period poorly represented in the Mediterranean terrestrial record. The results from Cova del Rinoceront are of broader interest for the reconstruction of ecological dynamics during warm stages and the understanding of the evolution and geographical variation of several taxa. The palaeoecological evidence suggests a landscape dominated by mixed wooded vegetation with mild climatic conditions, slightly more humid than today. Several vertebrate taxa, including Haploidoceros mediterraneus, Stephanorhinus hundsheimensis and Glis glis, are documented for the first time in the early Upper Pleistocene of Europe, showing that these species persisted across the region for longer than previously thought. In addition, the recovery of a small lithic assemblage indicates human presence in the surroundings of the site. The 11 m-thick stratigraphic section also provides an ideal setting in which to compare several geochronological methods. U-Th dating of the flowstones that cap the deposit, of speleothems formed along the cave walls, and of speleothems buried by the deposit at different elevations provides minimum and maximum ages of 74 and 175 ka, respectively, for the accumulation. The ages obtained by luminescence, electron spin resonance (ESR), amino acid racemisation (AAR), palaeomagnetism and U-series dating of bone are in good agreement with each other and are stratigraphically consistent. This well-dated faunal succession presents a unique opportunity to assess changes in the Pleistocene fauna of the Mediterranean coast over an interval of more than 100 ka.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4975556','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4975556"><span>Shatter cones: (<span class="hlt">Mis</span>)understood?</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Osinski, Gordon R.; Ferrière, Ludovic</p> <p>2016-01-01</p> <p>Meteorite impact craters are one of the most common geological features in the solar system. An impact event is a near-instantaneous process that releases a huge amount of energy over a very small region on a planetary surface. This results in characteristic changes in the target rocks, from vaporization and melting to solid-state effects, such as fracturing and shock metamorphism. Shatter cones are distinctive striated conical fractures that are considered unequivocal evidence of impact events. They are one of the most used and trusted shock-metamorphic effects for the recognition of meteorite impact structures. Despite this, there is still considerable debate regarding their formation. We show that shatter cones are present in several stratigraphic settings within and around impact structures. Together with the occurrence of complete and “double” cones, our observations are most consistent with shatter cone formation due to tensional stresses generated by scattering of the shock wave due to heterogeneities in the rock. On the basis of field mapping, we derive the relationship Dsc = 0.4 Da, where Dsc is the maximum spatial extent of in situ shatter cones, and Da is the apparent crater diameter. This provides an important, new, more accurate method to estimate the apparent diameter of eroded complex craters on Earth. We have reestimated the diameter of eight well-known impact craters as part of this study. Finally, we suggest that shatter cones may reduce the strength of the target, thus aiding crater collapse, and that their distribution in central uplifts also records the obliquity of impact. PMID:27532050</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27532050','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27532050"><span>Shatter cones: (<span class="hlt">Mis</span>)understood?</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Osinski, Gordon R; Ferrière, Ludovic</p> <p>2016-08-01</p> <p>Meteorite impact craters are one of the most common geological features in the solar system. An impact event is a near-instantaneous process that releases a huge amount of energy over a very small region on a planetary surface. This results in characteristic changes in the target rocks, from vaporization and melting to solid-state effects, such as fracturing and shock metamorphism. Shatter cones are distinctive striated conical fractures that are considered unequivocal evidence of impact events. They are one of the most used and trusted shock-metamorphic effects for the recognition of meteorite impact structures. Despite this, there is still considerable debate regarding their formation. We show that shatter cones are present in several stratigraphic settings within and around impact structures. Together with the occurrence of complete and "double" cones, our observations are most consistent with shatter cone formation due to tensional stresses generated by scattering of the shock wave due to heterogeneities in the rock. On the basis of field mapping, we derive the relationship D sc = 0.4 D a, where D sc is the maximum spatial extent of in situ shatter cones, and D a is the apparent crater diameter. This provides an important, new, more accurate method to estimate the apparent diameter of eroded complex craters on Earth. We have reestimated the diameter of eight well-known impact craters as part of this study. Finally, we suggest that shatter cones may reduce the strength of the target, thus aiding crater collapse, and that their distribution in central uplifts also records the obliquity of impact.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19710000428','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19710000428"><span>Manpower management information system /<span class="hlt">MIS</span>/</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Gravette, M. C.; King, W. L.</p> <p>1971-01-01</p> <p>System of programs capable of building and maintaining data bank provides all levels of management with regular manpower evaluation reports and data source for special management exercises on manpower.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006PhDT........50M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006PhDT........50M"><span>Processus <span class="hlt">mis</span> en jeu dans l'evolution morpho-dynamique de Roberts Bank (Delta du Fraser): Observation et modelisation hydrodynamiques et sedimentaires</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Meule, Samuel</p> <p></p> <p>Roberts Bank couvre le delta intertidal entre le bras principal du fleuve Fraser et la pointe du Cap Roberts en Colombie Britannique, Canada. Sous la pression du developpement urbain et la modification du regime sedimentaire, cette plage de sable fin est soumise a une erosion significative. L'identification des forces hydrodynamiques, leur importance et leur interaction permettent de determiner les zones de transport, et donc la stabilite de Roberts Bank. Deux periodes de mesures associees a des phases de modelisation de la houle et des courants ont ete effectuees lors de ce travail. La premiere periode de mesure, entre le 29 juin et le 8 juillet 2001, a permis l'identification de processus hydrodynamiques et sedimentaires associes aux forts courants de maree presents le long de Roberts Bank. La seconde phase de mesure, entre le 1er mars et le 26 mars 2002, a permis d'etudier les processus de remise en suspension associes a la houle. Des phases de modelisation ont ete menees a partir des connaissances acquises sur le terrain, afin d'affiner la comprehension des processus sedimentaires et notamment les interactions houle - courant - sediment. Les mecanismes, <span class="hlt">mis</span> en evidence dans cette etude, participent au faconnage de Roberts Bank, contribuent a son erosion et a la mise en place de nouvelles structures sedimentaires. Les courants de flot de maree vont initier la creation de nuages de resuspension de sediment depuis le fond. En eau peu profonde, la composante " onshore" du courant de maree induit un transport a la cote, tandis qu'en eau plus profonde une faible composante " offshore" du courant peut favoriser un transport au large le long de la pente. Les chenaux, les dunes subaquatiques et les surfaces d'erosion affleurantes fournissent une rugosite de fond suffisante a la generation de turbulence et donc de nuages de sediment en suspension. Lors de la maree de jusant, les sediments resuspendus en eau peu profonde, sont transportes vers le large a partir d</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25189330','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25189330"><span>Minimizing ultraviolet noise due to <span class="hlt">mis</span>-matches between detector flow cell and post column mobile phase temperatures in supercritical fluid chromatography: effect of flow cell design.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Berger, Terry A</p> <p>2014-10-17</p> <p>A <span class="hlt">mis</span>-match between the post-column mobile phase temperature and the UV detector flow cell temperature can cause significant UV noise in supercritical fluid chromatography (SFC). Deviations as little as 5 °C can increase noise as much as 5 times, making the detector unsuited for trace analysis. Two approaches were used to minimize this noise. When a flow cell was in direct thermal contact (metal on metal) with the detector optical bench, the mobile phase temperature was actively controlled to the measured flow cell temperature, by using one of the heat exchangers (HX) in the column compartment. However, with some older, but still widely used flow cell designs, this required repeated, hourly monitoring of the flow cell temperature and repeated manual adjustment of the heat exchanger temperature, due to thermal drift. Flow cell design had a strong influence on susceptibility to this thermally induced noise. Thermally insulating the flow cell from the optical bench made some cells much less susceptible to such thermally induced noise. Five different flow cells, some insulated, some un-insulated, were evaluated. Most had a truncated conical flow path, but one had a cylindrical flow path. Using either approach, the ASTM noise, with a 10mm, 13 μL conical flow cell, could be optimized to ≈0.007 mAU at 2.5 Hz, in SFC, which is very near the 0.006 mAU manufacturer's specification for HPLC. The insulated version of this flow cell required far less optimization, compared to the un-insulated version. At 150 bar, an experimental 3mm, 2 μL flow cell, with only one side insulated, yielded noise slightly too high (≈0.16-0.18 mAU) for trace analysis, at 80 Hz. However, at 200 bar, noise at 80 Hz was <0.06 mAU, which should allow quantification of a 1 mAU tall trace component with a signal to noise ratio (S/N) >10. Even partially un-insulated, this flow cell design was much less susceptible to thermally induced noise. Further insulating this flow cell design failed to improve</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015E%26PSL.429...69R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015E%26PSL.429...69R"><span>Surface exposure chronology of the Waimakariri glacial sequence in the Southern Alps of New Zealand: Implications for <span class="hlt">MIS</span>-2 ice extent and LGM glacial mass balance</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rother, Henrik; Shulmeister, James; Fink, David; Alexander, David; Bell, David</p> <p>2015-11-01</p> <p>During the late Quaternary, the Southern Alps of New Zealand experienced multiple episodes of glaciation with large piedmont glaciers reaching the coastal plains in the west and expanding into the eastern alpine forelands. Here, we present a new 10Be exposure age chronology for a moraine sequence in the Waimakariri Valley (N-Canterbury), which has long been used as a reference record for correlating glacial events across New Zealand and the wider Southern Hemisphere. Our data indicate that the Waimakariri glacier reached its maximum last glaciation extent prior to ∼26 ka well before the global last glaciation maximum (LGM). This was followed by a gradual reduction in ice volume and the abandonment of the innermost LGM moraines at about 17.5 ka. Significantly, we find that during its maximum extent, the Waimakariri glacier overflowed the Avoca Plateau, previously believed to represent a mid-Pleistocene glacial surface (i.e. <span class="hlt">MIS</span> 8). At the same time, the glacier extended to a position downstream of the Waimakariri Gorge, some 15 km beyond the previously mapped LGM ice limit. We use a simple steady-state mass balance model to test the sensitivity of past glacial accumulation to various climatic parameters, and to evaluate possible climate scenarios capable of generating the ice volume required to reach the full local-LGM extent. Model outcomes indicate that under New Zealand's oceanic setting, a cooling of 5 °C, assuming modern precipitation levels, or a cooling of 6.5 °C, assuming a one third reduction in precipitation, would suffice to drive the Waimakariri glacier to the eastern alpine forelands (Canterbury Plains). Our findings demonstrate that the scale of LGM glaciation in the Waimakariri Valley and adjacent major catchments, both in terms of ice volume and downvalley ice extent, has been significantly underestimated. Our observation that high-lying glacial surfaces, so far believed to represent much older glacial episodes, were glaciated during the LGM</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_14");'>14</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li class="active"><span>16</span></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_16 --> <div id="page_17" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="321"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015E%26PSL.428..281L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015E%26PSL.428..281L"><span>High-resolution OSL dating of a late Quaternary sequence from Xingkai Lake (NE Asia): Chronological challenge of the "<span class="hlt">MIS</span> 3a Mega-paleolake" hypothesis in China</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Long, Hao; Shen, Ji; Wang, Yong; Gao, Lei; Frechen, Manfred</p> <p>2015-10-01</p> <p>In this paper a combined OSL (49 samples) and 14C (14 samples) dating study was conducted on a sediment core from Xingkai Lake, NE Asia. A single-aliquot regenerative-dose protocol was used to determine the equivalent dose (De) of the extracted fine-grained (FG) quartz fraction; the suitability of the measurement procedure was confirmed by a set of luminescence tests (e.g., preheat plateau and dose recovery measurements). In addition, a post-IR infrared stimulated luminescence protocol at 290 °C (pIRIR290) was applied to the polymineral FG fraction of seven samples. Our results can be summarized as follows: (1) The uppermost sample was dated to ∼110 a, indicating that the OSL signal of FG quartz has been well bleached. This has been further confirmed by the consistency of OSL ages and pIRIR290 ages within <80 ka. The resulting OSL ages generally increased with depth, and the lowermost samples of core XK08 reached back to the last interglacial, although the pIRIR290 dating suggested that the quartz OSL ages likely begin to be underestimated beyond 80 ka; (2) The comparison of OSL and 14C ages suggested that the radiocarbon dating technique may significantly underestimate the age of sediments for samples older than 30 cal ka BP (corresponding to ∼25 14C ka BP), and thus it is necessary to pay attention when using such old 14C dates for paleoclimatic/archaeological interpretation; (3) This study challenges the radiocarbon-based chronology of the "<span class="hlt">MIS</span> 3a Mega-paleolake" hypothesis, which had been reiterated for many years and extensively reported across northern and western China; and (4) The current high-resolution OSL dating record (one-age/5-10 cm) showed clear sedimentation rate changes down the core. The identified variations in the sedimentation processes at the orbital timescale may be related to regional/global climatic changes during the past 130 ka, and the high sedimentation rate during the last ∼0.4 ka has probably been caused by intensified human</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010AGUFMPP51A1605H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010AGUFMPP51A1605H"><span>Land-Ocean Correlation of Orbital-Scale Climatic Changes in the Western Mediterranean during <span class="hlt">MIS</span> 1/2 and 11/12</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hambach, B.; Huang, Y.; Rosell Mele, A.</p> <p>2010-12-01</p> <p>The interval between 405 and 340 thousand years before present has been argued to be the most recent astronomical analogue for the last glacial and current interglacial period. This similarity is mainly a function of orbital scale climatic changes (eccentricity, precession). To gain a better insight into the Iberian peninsular climate and its transitions during these periods, a marine sediment core from the Alboran Sea, Western Mediterranean, is used to reconstruct climate relevant variables related to surface ocean, atmospheric circulation and hydrology by applying a set of organic geochemical proxies (biomarkers). The location of the core, between the African continent and the Iberian Peninsula make it especially interesting for investigating regional climate changes and transitions in an area with significant hominid remains. Here we present millennial scale resolution data (2 ky) for the interval from 0 to 130 and 374-484 ky corresponding to <span class="hlt">MIS</span> 1-6 and 11-12, respectively. The results of this multi-biomarker analysis give new insights into past ocean climate conditions as well as into the processes that occurred onshore during this period. The reconstruction of sea surface temperatures is done by the analysis of alkenones (UK37’-index). Chlorophyllic pigment concentration is used as proxy for paleoproductivity. Terrestrial eolian inputs and vegetation changes are determined by the analysis of n-alkyl compounds (long chain n-alkanes, n-alkenols and n-alkanoic acids) which are major components of leaf waxes from terrestrial higher plants. Like mineral aerosols, these compounds are wind-transported from terrestrial vegetation sources to adjacent oceans where the particles settle and are preserved in ocean sediments with very little diagenetic alteration. To assess hydrology related shifts in Iberian peninsular climate, the compound specific hydrogen isotope ratio in higher plant n-alkanes was used. These biomarkers offer a promising tool for reconstructing</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016QSRv..151..185R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016QSRv..151..185R"><span>Last Neanderthals and first Anatomically Modern Humans in the NW Iberian Peninsula: Climatic and environmental conditions inferred from the Cova Eirós small-vertebrate assemblage during <span class="hlt">MIS</span> 3</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Rey-Rodríguez, Iván; López-García, Juan-Manuel; Bennàsar, Maria; Bañuls-Cardona, Sandra; Blain, Hugues-Alexandre; Blanco-Lapaz, Ángel; Rodríguez-Álvarez, Xosé-Pedro; de Lombera-Hermida, Arturo; Díaz-Rodríguez, Mikel; Ameijenda-Iglesias, Alicia; Agustí, Jordi; Fábregas-Valcarce, Ramón</p> <p>2016-11-01</p> <p>Cova Eirós is emerging as a reference site in the northwestern Iberian Peninsula for the study of the development of the last Neanderthal populations and the first populations of Anatomically Modern Humans (AMH) in <span class="hlt">MIS</span> 3. Cova Eirós is an archaeological site (with Middle and Upper Palaeolithic levels) located in Cancelo, Triacastela (Lugo, northwestern Iberian Peninsula), which has been systematically excavated from 2008 onwards. The small-vertebrate assemblage analysed came from the archaeo-palaeontological field seasons that took place from 2009 to 2014. At least 18 small-vertebrate taxa have been identified: 1 frog (Rana temporaria), 1 snake (Vipera sp.), 4 insectivores (Sorex minutus, Sorex sp., Talpa cf. occidentalis and Erinaceus europaeus), 4 chiropters (Myotis myotis/blythii, cf. Miniopterus sp., Myotis sp. and Rhinolophus ferrumequinum) and 8 rodents (Apodemus sylvaticus, Arvicola amphibius, Arvicola sapidus, Chionomys nivalis, Microtus (Terricola) lusitanicus, Microtus agrestis, Microtus arvalis and Microtus oeconomus). Using the Habitat Weighting method to reconstruct the palaeoenvironment, we reconstruct a landscape for <span class="hlt">MIS</span> 3 characterized by open woodland formations. The Mutual Ecogeographic Range (MER) method and the Bioclimatic Model (BM) used for the palaeoclimatic reconstruction show lower temperatures and higher precipitation than at present in the region. Our results from Cova Eirós are compared with the data obtained from several other sites in the Iberian Peninsula; it can be said that Neanderthals and AMH were well adapted to the territory that they occupied, as well as to the surrounding environment and the climatic conditions prevalent in the unstable context of <span class="hlt">MIS</span> 3 in the Iberian Peninsula.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JPCS..102...42V','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JPCS..102...42V"><span>Admittance measurements in the temperature range (8-77) K for characterization of <span class="hlt">MIS</span> structures based on MBE n-Hg0.78Cd0.22Te with and without graded-gap layers</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Voitsekhovskii, A. V.; Nesmelov, S. N.; Dzyadukh, S. M.</p> <p>2017-03-01</p> <p>Admittance of <span class="hlt">MIS</span> structures based on MBE n-Hg1-xCdxTe (x=0.22-0.23) with Al2O3 as insulator is experimentally investigated for the cases of the presence and absence of near-surface graded-gap layers with high content of CdTe. It is shown that the structures with graded-gap layers are characterized by a significant hysteresis of electrical characteristics, a deep and broad dip in the low-frequency capacitance-voltage characteristic, and high values of the differential resistance of the space charge region in the strong inversion. It is found that already at 77 K, the capacitance-voltage characteristics of structures with graded-gap layers have a high-frequency behavior relative to the recharge time of surface states in the frequency range of (1-2000) kHz. At frequencies exceeding 200 kHz and a temperature of (9-15) K, the capacitance-voltage characteristics of the structures without graded-gap layers have a high-frequency behavior relative to the recharge time of surface states located near the Fermi energy for an intrinsic semiconductor. Peculiarities of determining the density of surface states and the electron concentration in <span class="hlt">MIS</span> structures with and without graded-gap layers are studied.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFMPP12A..04H','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFMPP12A..04H"><span>Combining 14C/U-Th Series Geochronology and Stable/Clumped Isotope Geochemistry of <span class="hlt">MIS</span> 2 Lake Tufas of Lake Chewaucan, Oregon, USA to Reconstruct Deglacial Climate in the Pacific Northwest</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Hudson, A. M.; Quade, J.; Ali, G.; Boyle, D. P.; Bassett, S.; Huntington, K. W.</p> <p>2015-12-01</p> <p>Shoreline deposits surrounding closed-basin lake remnants in the Great Basin of North America have been critical to defining the timing and extent of lake highstands during Marine Isotope Stage 2, recording the wettest climate conditions during the last glacial cycle. We present 14C and U-Th series ages and stable and clumped isotope results from <span class="hlt">MIS</span> 2 microbialite tufas of pluvial Lake Chewaucan, southern Oregon. At ~42.5°N latitude, the Chewaucan basin is the one of the northernmost lake systems in the Great Basin, a critical location for investigating regional climate. Dating of modern tufa and DIC indicates no 14C reservoir effect. Low lake depth is observed for peak LGM conditions (21.0 ka, +11 m above modern), consistent with regional records and climate model results. In contrast with other Great Basin lake reconstructions for deglacial <span class="hlt">MIS</span> 2, Lake Chewaucan was deepest during the Bølling/Ållerod (B/A; 14.5-13.0 ka, +50 m) and early Holocene (10.9-9.5 ka +15 m) warm periods, with lowstands during Heinrich Event 1 (+0-1 m) and Younger Dryas cold periods (+0 m). This supports previous evidence for wet interstadials in the Pacific Northwest (PNW) during <span class="hlt">MIS</span> 2-3, the opposite of the central/southern Great Basin, where stadials correlate with wet conditions. δ18O values of tufas (-0.9 to -4.4‰ PDB) reflect high evaporation relative to inflowing meteoric water (-13.6‰ SMOW), and lake water (-6.7 SMOW). δ13C values (+1.7 to +4.5‰ PDB) are consistent with equilibrium with lake DIC (+1.5‰ PDB) and atmospheric CO2, supporting atmospheric 14C equilibrium. Clumped isotope temperatures for modern tufa (20±7°C) are consistent with summer lake surface temperature for modern lake remnant, Abert Lake (17.7-22.0°C), supporting previous clumped isotope results for tufas as summer temperature indicators. Clumped temperatures for the B/A highstand are 19±4°C, indicating near modern lake temperatures during deepest lake conditions. 13±4°C is indicated for the</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=personal+AND+hygiene&pg=7&id=ED162487','ERIC'); return false;" href="http://eric.ed.gov/?q=personal+AND+hygiene&pg=7&id=ED162487"><span>Title <span class="hlt">VI-B</span> Evaluation Report 1976-77. New York State Education for the Handicapped Act.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cronk, George A., Jr.</p> <p></p> <p>The report summarizes pupil behavioral change data from 176 instructional projects involving handicapped children in New York state. Data are presented for reading achievement, mathematics achievement, and a broad category that encompassed language arts, corrective speech, psychomotor, auditory and visual perceptions, personal hygiene, societal…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015QSRv..107..149M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015QSRv..107..149M"><span>The Taimyr Peninsula and the Severnaya Zemlya archipelago, Arctic Russia: a synthesis of glacial history and palaeo-environmental change during the Last Glacial cycle (<span class="hlt">MIS</span> 5e-2)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Möller, Per; Alexanderson, Helena; Funder, Svend; Hjort, Christian</p> <p>2015-01-01</p> <p>We here suggest a glacial and climate history of the Taimyr Peninsula and Severnaya Zemlya archipelago in arctic Siberia for the last about 150 000 years (ka). Primarily it is based on results from seven field seasons between 1996 and 2012, to a large extent already published in papers referred to in the text - and on data presented by Russian workers from the 1930s to our days and by German colleagues working there since the 1990s. Although glaciations even up here often started in the local mountains, their culminations in this region invariably seems to have centred on the shallow Kara Sea continental shelf - most likely due to expanding marine ice-shelves grounding there, as a combined effect of thickening ice and eustatically lowered sea-levels. The most extensive glaciation so far identified in this region (named the Taz glaciation) took place during Marine Isotope Stage 6 (<span class="hlt">MIS</span> 6), i.e. being an equivalent to the late Saale/Illinoian glaciations. It reached c. 400 km southeast of the Kara Sea coast, across and well beyond the Byrranga Mountain range and ended c. 130 ka. It was followed by the <span class="hlt">MIS</span> 5e (Karginsky/Eemian) interglacial, with an extensive marine transgression to 140 m above present sea level - facilitated by strong isostatic downloading during the preceding glaciation. During the latest (Zyryankan/Weichselian/Wisconsinan) glacial cycle followed a series of major glacial advances. The earliest and most extensive, culminating c. 110-100 ka (<span class="hlt">MIS</span> 5d-5e), also reached south of the Byrranga mountains and its post-glacial marine limit there was c. 100 m a.s.l. The later glacial phases (around 70-60 ka and 20 ka) terminated at the North Taimyr Ice Marginal Zone (NTZ), along or some distance inland from the present northwest coast of Taimyr. They dammed glacial lakes, which caused the Taimyr River to flow southwards where to-day it flows northwards into the Kara Sea. The c. 20 ka glacial phase, contemporary with the maximum (LGM) glaciation in NW Europe</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016SeScT..31b5004W','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016SeScT..31b5004W"><span>High-temperature studies of multiple fluorinated traps within an Al2O3 gate dielectric for E-Mode AlGaN/GaN power <span class="hlt">MIS</span>-HEMTs</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Wang, Yun-Hsiang; Liang, Yung C.; Samudra, Ganesh S.; Chu, Po-Ju; Liao, Ya-Chu; Huang, Chih-Fang; Kuo, Wei-Hung; Lo, Guo-Qiang</p> <p>2016-02-01</p> <p>Normally-off AlGaN/GaN <span class="hlt">MIS</span>-HEMT devices with multiple fluorinated ALD-Al2O3 layers as the gate dielectric have been reported to achieve a high threshold voltage for normally-off operations with satisfactory performance for both on and off states at room temperature. However, a large swing in gate threshold voltage is found when devices operate at elevated temperatures. Hence, further study of the gate dielectric on the distribution of fluorinated trap states in the energy band are required to assess the gate function at higher temperatures. Through the use of the charge analytical model and Poole-Frenkel trap emission theory, the gate voltage stressing measurement was carried out to accurately find the effective trap state distribution within the Al2O3 energy bandgap created by fluorinated treatments. For the samples fabricated and used in the investigation, we found that a higher population of fluorinated trap states located deeper than 1.1 eV corresponding to emission levels above 200 °C would allow more trapped charges to remain in the dielectric at high temperature for better threshold voltage retention. We also discovered that a higher fluorine treatment power on the gate dielectric could yield a higher trap state density at deeper levels, resulting in better temperature stability.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/431179','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/431179"><span>Interfacial arsenic from wet oxidation of Al{sub x}Ga{sub 1-X}As/GaAs: Its effects on electronic properties and new approaches to <span class="hlt">MIS</span> device fabrication</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ashby, C.I.H.; Sullivan, J.P.; Newcomer, P.P.</p> <p>1996-12-31</p> <p>Three important oxidation regimes have been identified in the temporal evolution of the wet thermal oxidation of Al{sub x}Ga{sub 1-x}As (1 {ge} x {ge} 0.90) on GaAs: (1) oxidation of Al and Ga in the Al{sub x}Ga{sub 1-x}As alloy to form an amorphous oxide layer, (2) oxidative formation and elimination of elemental As (both crystalline and amorphous) and of amorphous As{sub 2}O{sub 3}, and (3) crystallization of the oxide film. Residual As can result in up to a 100-fold increase in leakage current and a 30% increase in the dielectric constant and produce strong Fermi-level pinning and high leakage currents at the oxidized Al{sub x}Ga{sub 1-x}As/GaAs interface. The presence of thermodynamically-favored interfacial As may impose a fundamental limitation on the application of AlGaAs wet oxidation for achieving <span class="hlt">MIS</span> devices in the GaAs material system.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Working+AND+place&pg=2&id=EJ1126070','ERIC'); return false;" href="http://eric.ed.gov/?q=Working+AND+place&pg=2&id=EJ1126070"><span>Exploring Pair Programming Benefits for <span class="hlt">MIS</span> Majors</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dongo, Tendai; Reed, April H.; O'Hara, Margaret</p> <p>2016-01-01</p> <p>Pair programming is a collaborative programming practice that places participants in dyads, working in tandem at one computer to complete programming assignments. Pair programming studies with Computer Science (CS) and Software Engineering (SE) majors have identified benefits such as technical productivity, program/design quality, academic…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=%22management+information+system%22&pg=4&id=EJ1063311','ERIC'); return false;" href="http://eric.ed.gov/?q=%22management+information+system%22&pg=4&id=EJ1063311"><span>Assurance of Learning in the <span class="hlt">MIS</span> Program</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Harper, Jeffrey S.; Harder, Joseph T.</p> <p>2009-01-01</p> <p>This article describes the development of a systematic and practical methodology for assessing program effectiveness and monitoring student development in undergraduate decision sciences programs. The model we present is based on a student's progression through learning stages associated with four key competencies: technical, analytical,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=digital+AND+media+AND+ethics&pg=2&id=EJ763733','ERIC'); return false;" href="http://eric.ed.gov/?q=digital+AND+media+AND+ethics&pg=2&id=EJ763733"><span>The (<span class="hlt">Mis</span>)Education of Generation M</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ziegler, Susan G.</p> <p>2007-01-01</p> <p>The focus of this paper is on the potential problems and challenges presented by the content, quantity and quality of contemporary media influences (electronic, print and digital). Whereas most articles in this arena focus on one form of media influences (e.g., video games), this article looks at the cumulative scope of influence presented by…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/7058620','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/7058620"><span>Transverse <span class="hlt">mis</span>-alignments in a driver</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Smith, L.; Hahn, K.</p> <p>1988-06-01</p> <p>The transverse errors of the beam lines are usually corrected by an appropriate feed back to bring the beam back on axis. In an induction linac, however, the head and tail of the bunch differ substantially in momentum at a given lens location. As a result, the correction has to be time dependent. Such a correction becomes increasingly difficult as the beam energy increases and the time duration of the bunch decreases. As a step towards an understanding of the problem, we have analyzed the extreme case of applying no correction. Since the lattice configuration changes and the transverse oscillations are damped as the ions are accelerated, the rms amplitude does not increase simply as the square root of the number of periods, as one would expect for constant velocity in a uniform channel. 2 refs., 2 figs.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ834155.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ834155.pdf"><span>Teachers' (<span class="hlt">Mis</span>)Understandings of Resilience</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Green, Deborah; Oswald, Murray; Spears, Barbara</p> <p>2007-01-01</p> <p>This study aimed to extend previous studies into resilience, by identifying the roles that teachers played in fostering resilience (N=57: females n=43; and males n=14). A quantitative scale was administered to teachers in South Australia's Catholic education sector to determine the extent to which they were involved in fostering resilience. A…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=nightmare&pg=4&id=EJ741307','ERIC'); return false;" href="http://eric.ed.gov/?q=nightmare&pg=4&id=EJ741307"><span>NCLB's Weapons of Mass <span class="hlt">Mis</span>-Instruction</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Houston, Paul D.</p> <p>2005-01-01</p> <p>In this article, the author discusses the nightmare educators face due to the No Child Left Behind Act meaning of "highly qualified" teachers. But for NCLB, highly qualified doesn't necessarily mean good, for them it means the teacher took the right number of subject-area courses in college and is teaching only those subjects. And that,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=goodwill&pg=6&id=EJ820477','ERIC'); return false;" href="http://eric.ed.gov/?q=goodwill&pg=6&id=EJ820477"><span>(<span class="hlt">Mis</span>-)Education into American Racism</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lin, Linda J.</p> <p>2007-01-01</p> <p>Background: Traditional approaches to race in the United States have located race in individuals and groups and reduced the ambiguities of interaction to differences in attitudes, levels of awareness, and stages of identity development. Alternatively, locating race in social stratification has made it an over-determined product of inequalities in…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Object+AND+Oriented+AND+Data+AND+Analysis&pg=3&id=EJ522473','ERIC'); return false;" href="http://eric.ed.gov/?q=Object+AND+Oriented+AND+Data+AND+Analysis&pg=3&id=EJ522473"><span>Two <span class="hlt">MIS</span> Analysis Methods: An Experimental Comparison.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Wang, Shouhong</p> <p>1996-01-01</p> <p>In China, 24 undergraduate business students applied data flow diagrams (DFD) to a mini-case, and 20 used object-oriented analysis (OOA). DFD seemed easier to learn, but after training, those using the OOA method for systems analysis made fewer errors. (SK)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015PMag...95.1049M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015PMag...95.1049M"><span>On double exponential forward bias current-voltage (I-V) characteristics of Au/Ca3Co4Ga0.001Ox/n-Si/Au (<span class="hlt">MIS</span>) type structures in temperature range of 80-340 K</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Marıl, E.; Altındal, Ş.; Kaya, A.; Koçyiğit, S.; Uslu, İ.</p> <p>2015-04-01</p> <p>Current transport mechanisms (CTMs) of Au/Ca3Co4Ga0.001Ox/n-Si/Au (<span class="hlt">MIS</span>) type structures were investigated using current-voltage (I-V) characteristics in the temperature range of 80-340 K. Semilogarithmic I-V plots show two linear regions corresponding to low (0.075-0.250 V) and moderate (0.27-0.70 V) biases, respectively. Zero-bias barrier height (ΦB0) was observed to increase with increase in the temperature, whereas opposite behaviour was observed for ideality factor (n). ΦB0 and (n-1-1) vesus q/2kT and ΦB0 versus n plots were drawn to get an evidence of Gaussian distribution (GD) of the barrier heights. These plots, too, show two linear regions corresponding to low (80-160 K) and high (200-340 K) temperature ranges (LTR and HTR), respectively. Mean value of barrier height (?B0) and standard deviation (σs) were extracted from the intercept and slope of ΦB0 versus q/2kT plots for two linear regions as 0.382 eV, 0.0060 V for LTR and 0.850 eV, 0.135 V for HTR at low biases and 0.364 eV, 0.0059 V for LTR and 0.806 eV, 0.132 V for HTR at high biases, respectively. ?B0 and Richardson constant (A*) values were also obtained from the intercept and slope of the modified Richardson (Ln(Io/T2)-(q2σs2/2k2T2) versus q/kT) plots as 131.81 Acm-2 K-2, 0.381 eV for LTR and 129.35 Acm-2 K-2, 0. 854 eV for HTR at low biases and 148.01 Acm-2 K-2, 0.377 eV for LTR and 143.77 Acm-2 K-2, 0.812 eV for HTR at high biases, respectively. In conclusion, CTM in the structure can be successfully explained in terms of thermionic emission theory with the double GD of barrier heights.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1985ITED...32.2780Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1985ITED...32.2780Y"><span>Fabrication of high-efficiency n(+)-p junction InP solar cells by using group <span class="hlt">VIb</span> element diffusion into p-type InP</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yamamoto, A.; Yamaguchi, M.; Uemura, C.</p> <p>1985-12-01</p> <p>The fabrication of n(+)-p homojunction InP solar cells has been studied using thermal diffusion of S, Se, or Te into p-type InP substrates. Sulphur diffusion using an In2S3 source was found to be effective in forming a shallow and steep n(+)-p function without surface morphology degradation of substrates. A conversion efficiency (active area) of 18 percent, which is the highest efficiency ever reported for InP homojunction solar cells, was obtained by optimizing fabrication conditions for sulphur-diffused cells. An electron irradiation study on fabricated cells has also been made. The InP solar cell was found to have a higher resistance to radiation degradation than Si and GaAs cells. Through these studies, it has been demonstrated that the InP solar cell has excellent potential for space applications.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JSV...376..246Y','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JSV...376..246Y"><span>Corrigendum to "An equation decoupling approach to identify the equivalent foundation in rotating machinery using modal parameters" [J. Sound <span class="hlt">Vib</span>. 365 (2016) 182-198</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Yu, Minli; Feng, Ningsheng; Hahn, Eric J.</p> <p>2016-08-01</p> <p>The authors would like to apologise for the error made to the affiliation details of Dr Ningsheng Feng and Dr Eric J. Hahn in the original publication and who are both affiliated to The School of Mechanical and Manufacturing Engineering, The University of New South Wales, Sydney, NSW 2052, Australia</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_15");'>15</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li class="active"><span>17</span></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_17 --> <div id="page_18" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="341"> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25591361','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25591361"><span>Direct observation of methyl rotor and <span class="hlt">vib</span>-rotor states of S0 toluene: a revised torsional barrier due to torsion-vibration coupling.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gascooke, Jason R; Virgo, Edwina A; Lawrance, Warren D</p> <p>2015-01-14</p> <p>We report a two dimensional, laser induced fluorescence study of the lowest 345 cm(-1) region of S0 toluene. Methyl rotor levels of 00 up to m = 6 and of 201 up to m = 4 are observed. The rotor levels of 00 and 201 have quite different energy spacings that are well fit by a model that includes strong torsion-vibration coupling between them. The model requires that the rotor barrier height be revised from -4.84 cm(-1) (methyl hydrogens in a staggered conformation) to +1.57 cm(-1) (eclipsed conformation). However, the 3a2″ state lies below the 3a1″ state as expected for a staggered conformation due to energy shifts associated with the torsion-vibration coupling. It is shown that the rotor wave-functions exhibit little localization at the torsional energy minima. The variation in the m = 0 wavefunction probability distribution with torsional angle is shown to be very similar for the previously accepted negative V6 value and the torsion-vibration coupling model as this coupling shifts the phase of the wavefunction by 30° compared with its phase for V6 alone. The presence of a strong Δυ = ± 1 torsion-vibration coupling involving the lowest frequency vibrational mode provides a potential pathway for rapid intramolecular vibrational energy redistribution at higher energies.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015IJMPB..2950237C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015IJMPB..2950237C"><span>On the negative capacitance behavior in the forward bias of Au/n-4H-SiC (MS) and comparison between MS and Au/TiO2/n-4H-SiC (<span class="hlt">MIS</span>) type diodes both in dark and under 200 W illumination intensity</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Çetinkaya, H. G.; Yıldız, D. E.; Altındal, Ş.</p> <p>2015-09-01</p> <p>In order to see the effect of interfacial layer on electrical characteristics both Au/n-4H-SiC (MS) and Au/TiO2/n-4H-SiC (<span class="hlt">MIS</span>) type Schottky barrier diodes (SBDs) were fabricated and their main electrical parameters were investigated by using the forward and reverse bias current-voltage (I-V), capacitance/conductance-voltage (C/G-V) measurements at room temperature. The ideality factor (n), series and shunt resistances (Rs, Rsh), barrier height (BH), depletion layer width (WD) and the concentration of donor atoms (ND) were obtained before and after illumination. The energy density distribution profile of surface states (Nss) was also obtained by taking into account voltage dependent effective BH (Φe) and ideality factor (nV). All of these experimental results confirmed that the use of a high dielectric material or insulator layer (TiO2) between metal and semiconductor leads to improvements in the diode performance in terms of Rs, Rsh, BH, Nss and rectifier rate (RR = IF/IR for sufficiently high forward and reverse current). Another important result is the negative capacitance (NC) behavior observed in the forward bias C-V plot for the Au/n-4H- SiC (MS) diode, but it disappears in Au/TiO2/n-4 H-SiC (<span class="hlt">MIS</span>) diode and also the minimum value of C-V plot corresponds to maximum value of G/ω-V plot in the accumulation region. Such behavior of NC shows that the material displays an inductive behavior.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5168833','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5168833"><span>Pancreatic Cancer, A <span class="hlt">Mis</span>-interpreter of the Epigenetic Language</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Iguchi, Eriko; Safgren, Stephanie L.; Marks, David L.; Olson, Rachel L.; Fernandez-Zapico, Martin E.</p> <p>2016-01-01</p> <p>Pancreatic cancer is the third leading cause of cancer mortality in the U.S. with close to 40,000 deaths per year. Pancreatic ductal adenocarcinoma (PDAC) represents approximately 90 percent of all pancreatic cancer cases and is the most lethal form of the disease. Current therapies for PDAC are ineffective and most patients cannot be treated by surgical resection. Most research efforts have primarily focused on how genetic alterations cause, alter progression, contribute to diagnosis, and influence PDAC management. Over the past two decades, a model has been advanced of PDAC initiation and progression as a multi-step process driven by the acquisition of mutations leading to loss of tumor suppressors and activation of oncogenes. The recognition of the essential roles of these genetic alterations in the development of PDAC has revolutionized our knowledge of this disease. However, none of these findings have turned into effective treatment for this dismal malignancy. In recent years, studies in the areas of chromatin modifications, and non-coding RNAs have uncovered mechanisms for regulating gene expression which occur independently of genetic alterations. Chromatin-based mechanisms are interwoven with microRNA-driven regulation of protein translation to create an integrated epigenetic language, which is grossly dysregulated in PDAC. Thus in PDAC, key tumor suppressors that are well established to play a role in PDAC may be repressed, and oncogenes can be upregulated secondary to epigenetic alterations. Unlike mutations, epigenetic changes are potentially reversible. Given this feature of epigenetic mechanisms, it is conceivable that targeting epigenetic-based events promoting and maintaining PDAC could serve as foundation for the development of new therapeutic and diagnostic approaches for this disease. PMID:28018146</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3497247','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3497247"><span>Person (<span class="hlt">mis</span>)perception: functionally biased sex categorization of bodies</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Johnson, Kerri L.; Iida, Masumi; Tassinary, Louis G.</p> <p>2012-01-01</p> <p>Social perception is among the most important tasks that occur in daily life, and perceivers readily appreciate the social affordances of others. Here, we demonstrate that sex categorizations are functionally biased towards a male percept. Perceivers judged body shapes that varied in waist-to-hip ratio to be men if they were not, in reality, exclusive to women, and male categorizations occurred more quickly than female categorizations (studies 1 and 4). This pattern was corroborated when participants identified the average body shapes of men and women (study 2) and when we assessed participants' cognitive representations (study 3). Moreover, these tendencies were modulated by emotion context (study 4). Thus, male categorizations occurred readily and rapidly, demonstrating a pronounced categorization bias and temporal advantage for male judgements. PMID:23075835</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19860017409&hterms=Antibiotics&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DAntibiotics','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19860017409&hterms=Antibiotics&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D70%26Ntt%3DAntibiotics"><span>Base pairing and base <span class="hlt">mis</span>-pairing in nucleic acids</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Wang, A. H. J.; Rich, A.</p> <p>1986-01-01</p> <p>In recent years we have learned that DNA is conformationally active. It can exist in a number of different stable conformations including both right-handed and left-handed forms. Using single crystal X-ray diffraction analysis we are able to discover not only additional conformations of the nucleic acids but also different types of hydrogen bonded base-base interactions. Although Watson-Crick base pairings are the predominant type of interaction in double helical DNA, they are not the only types. Recently, we have been able to examine mismatching of guanine-thymine base pairs in left-handed Z-DNA at atomic resolution (1A). A minimum amount of distortion of the sugar phosphate backbone is found in the G x T pairing in which the bases are held together by two hydrogen bonds in the wobble pairing interaction. Because of the high resolution of the analysis we can visualize water molecules which fill in to accommodate the other hydrogen bonding positions in the bases which are not used in the base-base interactions. Studies on other DNA oligomers have revealed that other types of non-Watson-Crick hydrogen bonding interactions can occur. In the structure of a DNA octamer with the sequence d(GCGTACGC) complexed to an antibiotic triostin A, it was found that the two central AT base pairs are held together by Hoogsteen rather than Watson-Crick base pairs. Similarly, the G x C base pairs at the ends are also Hoogsteen rather than Watson-Crick pairing. Hoogsteen base pairs make a modified helix which is distinct from the Watson-Crick double helix.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25716437','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25716437"><span>(<span class="hlt">Mis</span>)regulation--the case of commercial surrogacy.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mahajan, Tarang</p> <p>2015-01-01</p> <p>In the most recent attempt to regulate commercial surrogacy, the Ministry of Home Affairs (MHA) has issued a notice altering the category of visa for foreign nationals entering into commercial surrogacy arrangements from "tourist" to "medical". Upon close scrutiny, it becomes clear that this measure is a far too hasty and unprincipled step. Given the varying laws across different countries, commercial surrogacy has been an area marked by a fair amount of legal ambiguity and conflict, for example, with respect to the citizenship status of the child and legally accepted parentage of commissioning parents. The MHA's step towards addressing some of the dilemmas is, however, grossly inadequate and discriminatory. In spite of its seeming advantages, of some administrative and legal oversight of the industry, the notice will impact the existing practices in questionable ways since its provisions remain to be vetted through the lens of medical ethics and social justice. The measures, which are supposed to ensure legality, disambiguation and some degree of security for the commercial surrogate, end up giving a clean chit to the industry for the time being. If the step taken by the MHA was meant to be urgent, one wonders at the lack of motivation to strengthen public debate and produce a piece of legislation that can address the various concerns and dilemmas generated by the assisted reproductive technologies (ARTs). This is especially with reference to legislation that ensures the health and democratic rights of those who are at a disadvantage due to the power imbalance in commercial surrogacy arrangements.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/772850','SCIGOV-STC'); return false;" href="http://www.osti.gov/scitech/servlets/purl/772850"><span>REPORT ON THE MODELING OF THE LARGE <span class="hlt">MIS</span> CANS</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>E. MOODY; J. LYMAN; K. VEIRS</p> <p>2000-12-01</p> <p>Changes in gas composition and gas pressure for closed systems containing plutonium dioxide and water are studied using a model that incorporates both radiolysis and chemical reactions. The model is used to investigate the behavior of material stored in storage containers conforming to DOE-STD-3013-99 storage standard. Scaling of the container to allow use of smaller amounts of nuclear material in experiments designed to bound the behavior of all material destined for long-term storage is studied. It is found that the container volume must be scaled along with the amount of material to achieve applicable results.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15534519','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15534519"><span><span class="hlt">MIS</span> unicondylar knee arthroplasty: surgical approach and early results.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gesell, Mark W; Tria, Alfred J</p> <p>2004-11-01</p> <p>Unicondylar arthroplasty of the knee has seen a resurgence of interest in the United States. The principles of unicondylar arthroplasty of the knee are different from those for total knee arthroplasty, allowing replacement of only the affected joint compartment with less bone loss. Minimally invasive surgery allows for less soft tissue dissection with the potential for less morbidity. The key question is: will the changes associated with the minimally invasive surgery procedure improve the clinical results of the standard unicondylar arthroplasty of the knee or will the changes make the procedure too difficult and lead to an increasing failure rate? This study reviews the surgical technique and presents the 2 to 4 year results of the minimally invasive unicondylar arthroplasty of the knee 47 knees in 41 patients. The average range of motion increased from 121 degrees -132 degrees . The Knee Society pain score improved from 45-80 and the function score improved from 47-78. Only one knee has been revised. With proper patient selection, minimally invasive unicondylar arthroplasty of the knee allows for results that are at least equal to those of the standard open procedure at 2 to 4 years after the surgery.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=switch&pg=5&id=EJ1111065','ERIC'); return false;" href="http://eric.ed.gov/?q=switch&pg=5&id=EJ1111065"><span>Second Career Teachers and (<span class="hlt">Mis</span>)Recognitions of Professional Identities</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Nielsen, Ann</p> <p>2016-01-01</p> <p>Since the late 1980s there has been an increase of "second career teachers" (SCTs), professionals that switch careers to become teachers. Little is known about SCTs and their sense of professional identity. Building from Pierre Bourdieu's concepts of power and cultural capital, the professional identities of teachers were examined…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=discourse+AND+media&pg=5&id=EJ968682','ERIC'); return false;" href="http://eric.ed.gov/?q=discourse+AND+media&pg=5&id=EJ968682"><span>Child Soldiers and Iconography: Portrayals and (<span class="hlt">Mis</span>)Representations</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Denov, Myriam</p> <p>2012-01-01</p> <p>Over the past decade, child soldiers have inundated the popular media. Images of boys armed with AK47s appear ubiquitous, providing a cautionary tale of innocent childhood gone awry. While these representations turn commonly held assumptions of a protected and innocuous childhood on its head, what they conceal is as provocative as what they…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/24951636','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/24951636"><span>Feeling (<span class="hlt">Mis</span>)Understood and Intergroup Friendships in Interracial Interactions.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Shelton, Nicole; Douglass, Sara; Garcia, Randi L; Yip, Tiffany; Trail, Thomas E</p> <p>2014-09-01</p> <p>The present research investigated whether having out-group friends serves as a buffer for feeling misunderstood in interracial interactions. Across three experience sampling studies, we found that among ethnic minorities who have few White friends or are not interacting with White friends, daily interracial interactions are associated with feeling less understood. By contrast, we found that among ethnic minorities who have more White friends or are interacting with White friends, the relationship between daily interracial interactions and feeling understood is not significant. We did not find similar results for Whites; that is, having ethnic minority friends did not play a role in the relationship between daily interracial interactions and feeling understood. Together, these studies demonstrate the beneficial effects of intergroup friendships for ethnic minorities.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=marketing&pg=4&id=EJ972746','ERIC'); return false;" href="http://eric.ed.gov/?q=marketing&pg=4&id=EJ972746"><span>Marketing Feud: An Active Learning Game of (<span class="hlt">Mis</span>)Perception</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Schee, Brian A. Vander</p> <p>2011-01-01</p> <p>This paper presents the results of implementing an active learning activity in the principles of marketing course adapted from the television show "Family Feud". The objectives of the Marketing Feud game include increasing awareness of marketing misperceptions, clarifying marketing misunderstandings, encouraging class participation, and building…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=third+AND+language+AND+acquisition&pg=6&id=EJ1078670','ERIC'); return false;" href="http://eric.ed.gov/?q=third+AND+language+AND+acquisition&pg=6&id=EJ1078670"><span>Do Null Subjects (<span class="hlt">Mis</span>-)Trigger Pro-Drop Grammars?</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Frazier, Lyn</p> <p>2015-01-01</p> <p>Native speakers of English regularly hear sentences without overt subjects. Nevertheless, they maintain a [[superscript -]pro] grammar that requires sentences to have an overt subject. It is proposed that listeners of English recognize that speakers reduce predictable material and thus attribute null subjects to this process, rather than changing…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28018146','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28018146"><span>Pancreatic Cancer, A <span class="hlt">Mis</span>-interpreter of the Epigenetic Language.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Iguchi, Eriko; Safgren, Stephanie L; Marks, David L; Olson, Rachel L; Fernandez-Zapico, Martin E</p> <p>2016-12-01</p> <p>Pancreatic cancer is the third leading cause of cancer mortality in the U.S. with close to 40,000 deaths per year. Pancreatic ductal adenocarcinoma (PDAC) represents approximately 90 percent of all pancreatic cancer cases and is the most lethal form of the disease. Current therapies for PDAC are ineffective and most patients cannot be treated by surgical resection. Most research efforts have primarily focused on how genetic alterations cause, alter progression, contribute to diagnosis, and influence PDAC management. Over the past two decades, a model has been advanced of PDAC initiation and progression as a multi-step process driven by the acquisition of mutations leading to loss of tumor suppressors and activation of oncogenes. The recognition of the essential roles of these genetic alterations in the development of PDAC has revolutionized our knowledge of this disease. However, none of these findings have turned into effective treatment for this dismal malignancy. In recent years, studies in the areas of chromatin modifications, and non-coding RNAs have uncovered mechanisms for regulating gene expression which occur independently of genetic alterations. Chromatin-based mechanisms are interwoven with microRNA-driven regulation of protein translation to create an integrated epigenetic language, which is grossly dysregulated in PDAC. Thus in PDAC, key tumor suppressors that are well established to play a role in PDAC may be repressed, and oncogenes can be upregulated secondary to epigenetic alterations. Unlike mutations, epigenetic changes are potentially reversible. Given this feature of epigenetic mechanisms, it is conceivable that targeting epigenetic-based events promoting and maintaining PDAC could serve as foundation for the development of new therapeutic and diagnostic approaches for this disease.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=online+AND+marketing&pg=2&id=EJ839110','ERIC'); return false;" href="http://eric.ed.gov/?q=online+AND+marketing&pg=2&id=EJ839110"><span>Using Google AdWords in the MBA <span class="hlt">MIS</span> Course</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Rosso, Mark A.; McClelland, Marilyn K.; Jansen, Bernard J.; Fleming, Sundar W.</p> <p>2009-01-01</p> <p>From February to June 2008, Google ran its first ever student competition in sponsored Web search, the 2008 Google Online Marketing Challenge (GOMC). The 2008 GOMC was based on registrations from 61 countries: 629 course sections from 468 universities participated, fielding over 4000 student teams of approximately 21,000 students. Working with a…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12319795','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12319795"><span>The making of Amerexico: (<span class="hlt">mis</span>)handling illegal immigration.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Andreas, P</p> <p>1994-01-01</p> <p>The border and social policies that the United States shares with Mexico have had only a modest impact on the level of illegal immigration. Alternative methods could reduce the social backlash against Mexican immigrants in US states of destination. Federal Relief Aid to states affected by new arrivals would ameliorate hostility. Although economic stagnation may depress the flow of immigrants or job opportunities, legal or illegal, economic recovery is dependent on the hard work of immigrants. The political solution has been to tighten border controls. Other options are possible. There should be pressure placed on multilateral institutions such as the World Bank and the International Monetary Fund to incorporate immigration issues in economic policy decisions. Many market reforms have contributed to greater emigration. The US has the option to use both supply and demand side options. Enforcement of workplace rules on minimum wages and health and safety standards would make it more difficult to exploit immigrant workers and would decrease the incentive to hire illegal workers. In a deregulated market stricter work standards were considered difficult to attain. A 1993 opinion poll revealed that 65% thought immigration was not beneficial. Border apprehension rates have increased dramatically over the past 30 years. The most recent policies aim to encourage the mobility of capital and trade through the NAFTA free trade agreement while trying to discourage human resource mobility. The push factors in Mexico are identified as high levels of poverty and unemployment, overpopulation, and economic stagnation. NAFTA and prior economic development efforts have not addressed the push factors. Disruption of traditional ways and changes toward greater industrialization spur emigration. The US program to develop border export industry encouraged migration from the interior of Mexico to border areas. Recent Mexican policies have changed the incentives for small farmers to stay on their lands, and Mexican urban areas are overpopulated. Experience has taught that migration flows are easier to start than stop.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Abortion&pg=4&id=EJ937331','ERIC'); return false;" href="http://eric.ed.gov/?q=Abortion&pg=4&id=EJ937331"><span>A Hollywood View of Christian <span class="hlt">Mis</span>-Education</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Resnick, David</p> <p>2011-01-01</p> <p>"Saved!" is the first Hollywood movie to focus on private religious education and is therefore a significant milestone in popular culture. The movie is critical of the school along the very dimensions of concern to Brighouse (2006): undermining personal autonomy, fostering social divisiveness, and promoting anti-democratic values. This article is…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21494917','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21494917"><span>The (<span class="hlt">mis</span>)reporting of statistical results in psychology journals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bakker, Marjan; Wicherts, Jelte M</p> <p>2011-09-01</p> <p>In order to study the prevalence, nature (direction), and causes of reporting errors in psychology, we checked the consistency of reported test statistics, degrees of freedom, and p values in a random sample of high- and low-impact psychology journals. In a second study, we established the generality of reporting errors in a random sample of recent psychological articles. Our results, on the basis of 281 articles, indicate that around 18% of statistical results in the psychological literature are incorrectly reported. Inconsistencies were more common in low-impact journals than in high-impact journals. Moreover, around 15% of the articles contained at least one statistical conclusion that proved, upon recalculation, to be incorrect; that is, recalculation rendered the previously significant result insignificant, or vice versa. These errors were often in line with researchers' expectations. We classified the most common errors and contacted authors to shed light on the origins of the errors.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=ecommerce&pg=6&id=EJ807697','ERIC'); return false;" href="http://eric.ed.gov/?q=ecommerce&pg=6&id=EJ807697"><span>Adding XML to the <span class="hlt">MIS</span> Curriculum: Lessons from the Classroom</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Wagner, William P.; Pant, Vik; Hilken, Ralph</p> <p>2008-01-01</p> <p>eXtensible Markup Language (XML) is a new technology that is currently being extolled by many industry experts and software vendors. Potentially it represents a platform independent language for sharing information over networks in a way that is much more seamless than with previous technologies. It is extensible in that XML serves as a "meta"…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2006PhyA..363..469E','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2006PhyA..363..469E"><span>The <span class="hlt">mis</span>-specification of the expected rescaled adjusted range</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ellis, Craig</p> <p>2006-05-01</p> <p>Rescaled range analysis has regained popularity in the recent econophysics literature as a means of identifying long-term dependence in time-series data. Conclusions derived from the rescaled adjusted range statistic are conditional however upon the choice of an appropriate benchmark against which calculated results can be compared. One recent paper in Physica A by Couillard and Davison [Physica A 348 (2005) 404] concludes that the Anis and Lloyd [Biometrika 63 (1976) 111] model of the expected rescaled adjusted range is more accurate than that proposed by Peters [Fractal Market Analysis, Wiley, New York, 1994]. This finding is contrary to the evidence presented by Peters. This paper reveals significant inconsistencies in the empirical results reported by Peters, which when considered, support the conclusions of Couillard and Davison and explain the apparent contradiction in their results versus those of Peters.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_16");'>16</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li class="active"><span>18</span></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_18 --> <div id="page_19" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="361"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Environmental+AND+topics&pg=7&id=EJ638023','ERIC'); return false;" href="http://eric.ed.gov/?q=Environmental+AND+topics&pg=7&id=EJ638023"><span>Environmental <span class="hlt">Mis</span>-Education? Addressing the Criticisms of Environmental Education.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hanuscin, Deborah</p> <p>2001-01-01</p> <p>Speculates on the negative effects on children while focusing on saving the environment. Proposes that children have been frightened by the presentation of this information and suggests acceptable ways of integrating environmental education topics into the curriculum. (DDR)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=corporate+AND+governance&pg=6&id=EJ769276','ERIC'); return false;" href="http://eric.ed.gov/?q=corporate+AND+governance&pg=6&id=EJ769276"><span>The University Revisioned: An Alternative to Corporate <span class="hlt">Mis</span>-Education</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lustig, Jeff</p> <p>2005-01-01</p> <p>Corporatization refers not only to the subordination of academic programs to outside business interest, but also to the more troubling intrusion of corporate forms of governance and market criteria of performance into the institution as a whole. In this paper, the author wants to show how this corporatization affects the substance, structure and…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=lisa&pg=7&id=ED529870','ERIC'); return false;" href="http://eric.ed.gov/?q=lisa&pg=7&id=ED529870"><span>Black School White School: Racism and Educational (<span class="hlt">Mis</span>) Leadership</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Brooks, Jeffrey S.</p> <p>2012-01-01</p> <p>How do race and race relations influence leadership practice and the education of students? In this timely and provocative book, the author identifies cultural and unstated norms and beliefs around race and race relations, and explores how these dynamics influence the kind of education students receive. Drawing on findings from extensive…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015JSV...339..433A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015JSV...339..433A"><span>Corrigendum to "Free vibration analysis of a cracked shear deformable beam on a two-parameter elastic foundation using a lattice" [ J. Sound <span class="hlt">Vib</span>. 333 (11) (2014) 2359-2377</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Attar, M.; Karrech, A.; Regenauer-Lieb, K.</p> <p>2015-03-01</p> <p>The authors have recently noticed that there are two missing references in the introduction of the article which are substantial as they describe the original motivation for this work and properly reference academic guidance and support that underpin the early phases of this project. The first author would also like to include an acknowledgement from two scholars in the acknowledgements section of the article. The authors apologize for this oversight.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://pubs.er.usgs.gov/publication/70034964','USGSPUBS'); return false;" href="http://pubs.er.usgs.gov/publication/70034964"><span>New optically stimulated luminescence ages provide evidence of <span class="hlt">MIS</span>3 and <span class="hlt">MIS</span>2 eolian activity on Black Mesa, northeastern Arizona, USA</span></a></p> <p><a target="_blank" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Ellwein, A.L.; Mahan, S.A.; McFadden, L.D.</p> <p>2011-01-01</p> <p>Eolian deposition on the semiarid southern Colorado Plateau has been attributed to episodic aridity during the Quaternary Period. However, OSL ages from three topographically controlled (e.g. falling) dunes on Black Mesa in northeastern Arizona indicate that eolian sediments there were deposited in deep tributary valleys as early as 35-30. ka, with most sand deposited before 20. ka. In contrast, the oldest OSL ages for sand sheets fall within the Pleistocene-Holocene climatic transition (~. 12-8. ka). Thus most eolian sediment accumulated on Black Mesa under climatic conditions that were in general cooler, moister, and more variable than today, not more arid, pointing to a considerable increase in sediment supply. ?? 2010 University of Washington.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=cafe&pg=3&id=EJ861246','ERIC'); return false;" href="http://eric.ed.gov/?q=cafe&pg=3&id=EJ861246"><span>Listening to "The Thick Bunch": (<span class="hlt">Mis</span>)Understanding and (<span class="hlt">Mis</span>)Representation of Young People in Jobs without Training in the South West of England</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lawy, Robert; Quinn, Jocey; Diment, Kim</p> <p>2009-01-01</p> <p>Young people in jobs without training are ubiquitous but invisible, working in shops, cafes, and other low-waged, low-status occupations. Commonly elided with young people who are not in education, employment or training, they are positioned as the "thick bunch" with empty and meaningless working lives. The main purpose of the research was to…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18464411','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18464411"><span>Electrical and memory properties of Si3N4 <span class="hlt">MIS</span> structures with embedded Si nanocrystals.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Horváth, Z J; Basa, P; Jászi, T; Pap, A E; Dobos, L; Pécz, B; Tóth, L; Szöllosi, P; Nagy, K</p> <p>2008-02-01</p> <p>Memory structures with an embedded sheet of separated Si nanocrystals were prepared by low pressure chemical vapour deposition using a Si3N4 control layer and different Si2O2 or Si3N4 tunnel layers. It was obtained that Si nanocrystals improve the charging behaviour of the MNOS structures. Memory window width of 1.3 V and 2.0 V were obtained for pulse amplitudes of +/-9 V and +/-10 V, 100 ms, respectively. The extrapolated memory window after 10 years is about 15% of its initial value.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/260542','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/260542"><span>A slanted etching method to analyze the trapped charge distribution in the insulators of <span class="hlt">MIS</span> structures</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Ohnishi, K.; Takahashi, Y.; Imaki, S.; Okada, K.; Yoshikawa, M.</p> <p>1995-12-31</p> <p>There are problems concerned with reliability of integrated circuits due to charge trapping in the oxide such as hot carrier injection, ionizing radiation, etc. Trapped charges in the insulators change the threshold voltage of MOSFET and increase the leakage currents in IC. Generally, the density of oxide charge has been calculated by assuming that it is located near the Si-SiO{sub 2} interface. This assumption is a good approximation in many cases. However, it would introduce serious errors in cases where the oxide charge has a spatial distribution, in particular where both positive and negative charges are present. In this paper, the authors propose a method for measuring the charge distribution in the oxide layer. They will explain about the slanted etching method that they proposed and describe the results of applying this method to silicon dioxide with and without ammonia anneal and silicon dioxide-nitride films. They will investigate the charge distributions both in the oxide layer of MOS structure with and without ammonia annealing and in the insulators of MOS and MNOS structures before and after irradiation.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25604846','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25604846"><span>Potential (<span class="hlt">Mis</span>)match? Marriage Markets Amidst Sociodemographic Change in India, 2005-2050.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kashyap, Ridhi; Esteve, Albert; García-Román, Joan</p> <p>2015-02-01</p> <p>We explore the impact of sociodemographic change on marriage patterns in India by examining the hypothetical consequences of applying three sets of marriage pairing propensities-contemporary patterns by age, contemporary patterns by age and education, and changing propensities that allow for greater educational homogamy and reduced educational asymmetries--to future population projections. Future population prospects for India indicate three trends that will impact marriage patterns: (1) female deficit in sex ratios at birth; (2) declining birth cohort size; (3) female educational expansion. Existing literature posits declining marriage rates for men arising from skewed sex ratios at birth (SRBs) in India's population. In addition to skewed SRBs, India's population will experience female educational expansion in the coming decades. Female educational expansion and its impact on marriage patterns must be jointly considered with demographic changes, given educational differences and asymmetries in union formation that exist in India, as across much of the world. We systematize contemporary pairing propensities using data from the 2005-2006 Indian National Family Health Survey and the 2004 Socio-Economic Survey and apply these and the third set of changing propensities to multistate population projections by educational attainment using an iterative longitudinal projection procedure. If today's age patterns of marriage are viewed against age/sex population composition until 2050, men experience declining marriage prevalence. However, when education is included, women--particularly those with higher education--experience a more salient rise in nonmarriage. Significant changes in pairing patterns toward greater levels of educational homogamy and gender symmetry can counteract a marked rise in nonmarriage.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://pubs.er.usgs.gov/publication/70137531','USGSPUBS'); return false;" href="http://pubs.er.usgs.gov/publication/70137531"><span>Directly dated <span class="hlt">MIS</span> 3 lake-level record from Lake Manix, Mojave Desert, California, USA</span></a></p> <p><a target="_blank" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Reheis, Marith; Miller, David M.; McGeehin, John P.; Redwine, Joanna R.; Oviatt, Charles G.; Bright, Jordon E.</p> <p>2015-01-01</p> <p>An outcrop-based lake-level curve, constrained by ~ 70 calibrated 14C ages on Anodonta shells, indicates at least 8 highstands between 45 and 25 cal ka BP within 10 m of the 543-m upper threshold of Lake Manix in the Mojave Desert of southern California. Correlations of Manix highstands with ice, marine, and speleothem records suggest that at least the youngest three highstands coincide with Dansgaard–Oeschger (D–O) stadials and Heinrich events 3 and 4. The lake-level record is consistent with results from speleothem studies in the Southwest that indicate cool wet conditions during D–O stadials. Notably, highstands between 43 and 25 ka apparently occurred at times of generally low levels of pluvial lakes farther north as interpreted from core-based proxies. Mojave lakes may have been supported by tropical moisture sources during oxygen-isotope stage 3, perhaps controlled by southerly deflection of Pacific storm tracks due to weakening of the sea-surface temperature gradient in response to North Atlantic climate perturbations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA462143','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA462143"><span>Mullerian Inhibiting Substances (<span class="hlt">MIS</span>) Augments IFN-gamma Mediated Inhibition of Breast Cancer Cell Growth</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2006-06-01</p> <p>transgenic mouse model carries the SV40 large T antigen targeted to the epithelium of the mammary and prostate glands andprogression of disease in these...mIFN-g 3) 100 ng mIFN-g each day for 5 days a week for 5 weeks. Two weeks after the start of treament animals started having palpable tumors which</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15030635','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15030635"><span>Evolving informational credentials: the (<span class="hlt">mis</span>)attribution of believable facts to credible sources.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Fragale, Alison R; Heath, Chip</p> <p>2004-02-01</p> <p>Three studies demonstrate that individuals often rely on a "belief force equals credible source" heuristic to make source judgments, wherein they assume that statements they believe originate from credible sources. In Study 1, participants who were exposed to a statement many times (and hence believed it) were more likely to attribute it to Consumer Reports than to the National Enquirer. In Study 2, participants read a murder investigation article containing evidence against two suspects from credible and noncredible sources. When participants believed a particular suspect to be guilty, they misattributed evidence incriminating that suspect to the high-credibility source. Study 3 demonstrated that this phenomenon occurs because individuals assume their beliefs are true and that true beliefs come from credible sources; when participants were given feedback that their beliefs were incorrect, the relationship between beliefs and source inferences did not occur.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=gun&pg=6&id=EJ829709','ERIC'); return false;" href="http://eric.ed.gov/?q=gun&pg=6&id=EJ829709"><span>The Silence of Fear: Making Sense of Student (<span class="hlt">Mis</span>)Behavior</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Peterek-Bonner, Emily</p> <p>2009-01-01</p> <p>The purpose of this personal narrative is to retrospectively analyze the actions and reactions of a young, female, white teacher who was faced with the reality of the dichotomy of race and power in a large school system. When an African American male student brings a gun to school, the teacher's personal assumptions come to the forefront, bringing…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=cobol&pg=2&id=EJ531844','ERIC'); return false;" href="http://eric.ed.gov/?q=cobol&pg=2&id=EJ531844"><span>CIS/<span class="hlt">MIS</span> Curriculums in AACSB-Accredited Colleges of Business.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Maier, J. Lee; Gambill, Stan</p> <p>1996-01-01</p> <p>Of 108 business colleges with computer information systems/management information systems majors, 43 responded to a survey. Curricula appear slow to respond to current needs. COBOL programming is still very popular. Only one management-type course is offered. (SK)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=punishment+AND+crime+AND+journal&pg=2&id=EJ790184','ERIC'); return false;" href="http://eric.ed.gov/?q=punishment+AND+crime+AND+journal&pg=2&id=EJ790184"><span>Film, Crime, and State Legitimacy: Political Education or <span class="hlt">Mis</span>-Education?</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Sankowski, Edward</p> <p>2002-01-01</p> <p>Film and related media are an important source of visually centered narratives in many contemporary cultures. This essay focuses on recent crime stories (particularly in the United States) conveyed through these media. In what follows, the emphasis is on film, but the issues could often be adapted to apply to other media that use moving images.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=meaning+AND+thesis&pg=7&id=EJ983457','ERIC'); return false;" href="http://eric.ed.gov/?q=meaning+AND+thesis&pg=7&id=EJ983457"><span>Applied Derrida: (<span class="hlt">Mis</span>)Reading the Work of Mourning in Educational Research</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lather, Patti</p> <p>2003-01-01</p> <p>Whatever the meaning of the "post" these days, it is pervasive, elusive and marked by a proliferation of conflicting definitions that refuse to settle into meaning. Efforts to accommodate/incorporate the "post" in educational research have not been easy. In the pages of the "Educational Researcher" alone, McLaren and Farahmandpur (2000) warn…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Scientific+AND+Work&pg=6&id=EJ891727','ERIC'); return false;" href="http://eric.ed.gov/?q=Scientific+AND+Work&pg=6&id=EJ891727"><span>(<span class="hlt">Mis</span>)Understanding Human Beings: Theory, Value, and Progress in Education Research</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hostetler, Karl</p> <p>2010-01-01</p> <p>There is renewed interest in what can be called an "experimentist" approach to education research. The claim is that if researchers would focus on experiments and "evidence-based" policies and practices, irreversible progress in education can be achieved. This experimentist approach cannot provide the understanding of knowledge and human beings…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA222174','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA222174"><span>Verification and Validation of the Integrated Maintenance Information System (<span class="hlt">MIS</span>) Diagnostic Module</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1990-05-01</p> <p>the result is inefficient diagnostics (extra steps required) rather than a failure of diagnostics. Handling of Maintance Actions The diagnostic module...corrupted data baseon the proper operation of the diagnostic module. The error sources examined included.h.rman error h entering data, machine (software</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26336359','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26336359"><span>The <span class="hlt">mis</span>-measurement of extreme global poverty: A case study in the Pacific Islands.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Deeming, Christopher; Gubhaju, Bina</p> <p>2015-09-01</p> <p>Debate over the measurement of global poverty in low- and middle-income countries continues unabated. There is considerable controversy surrounding the 'dollar a day' measure used to monitor progress against the Millennium Development Goals. This article shines fresh light on the debate with new empirical analyses of poverty (including child poverty), inequality and deprivation levels in the Pacific island state of Vanuatu. The study focuses not only on economic and monetary metrics and measures, but also the measures of deprivation derived from sociology in relation to shelter, sanitation, water, information, nutrition, health and education. Until recently, there had been few, if any, attempts to study poverty and deprivation disparities among children in this part of the world. Different measures yield strikingly different estimates of poverty. The article, therefore, attempts to situate the study findings in the broader international context of poverty measurement and discusses their implications for future research and the post-2015 development agenda.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=refugee+AND+concerns&id=EJ986780','ERIC'); return false;" href="http://eric.ed.gov/?q=refugee+AND+concerns&id=EJ986780"><span>Pursuing Justice for Refugee Students: Addressing Issues of Cultural (<span class="hlt">Mis</span>)Recognition</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Keddie, Amanda</p> <p>2012-01-01</p> <p>In this paper Nancy Fraser's conceptual tools are drawn on to theorise issues of justice in a culturally diverse primary school in Australia where approximately 30% of the student population are immigrant/refugees. The paper examines justice issues of cultural recognition in relation to refugee student identity, behaviour and assessment. Drawing…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_17");'>17</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li class="active"><span>19</span></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_19 --> <div id="page_20" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="381"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA114498','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA114498"><span>Feasibility and Requirements Analysis of <span class="hlt">MIS</span> for Operational Patrol Squadrons in the United States Navy.</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1981-12-01</p> <p>future trends based on training information. n. Merge resource and production data to produce significant measures of training performance, faeilitate...ATSS software can be classified as System Support Software and Aviation Applications Software and each will be liscussed seperately . a. System Support...a par: of the other system software or may be provide as a seperate software package. b. Application Software The applications software for NALCOMIS</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=lockers+NOT+Diablo+NOT+Toro+NOT+vacio&pg=6&id=ED495057','ERIC'); return false;" href="http://eric.ed.gov/?q=lockers+NOT+Diablo+NOT+Toro+NOT+vacio&pg=6&id=ED495057"><span><span class="hlt">Mis</span>-Education in Schools: Beyond the Slogans and Double-Talk</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Good, Howard</p> <p>2006-01-01</p> <p>In this book, the author uses his experiences as a parent, teacher, and school board member to explore what has gone wrong with education and how to make it right. He takes the reader inside classrooms, locker rooms, school board meetings, and parent-teacher conferences to discover how children are being educated--or, more often than not,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016yCat..35820021B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016yCat..35820021B"><span>VizieR Online Data Catalog: Merging galaxies (<span class="hlt">mis</span>)alignments (Barrera-Ballesteros+, 2015)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Barrera-Ballesteros, J. K.; Garcia-Lorenzo, B.; Falcon-Barroso, J.; van de Ven, G.; Lyubenova, M.; Wild, V.; Mendez-Abreu, J.; Sanchez, S. F.; Marquez, I.; Masegosa, J.; Monreal-Ibero, A.; Ziegler, B.; Del Olmo, A.; Verdes-Montenegro, L.; Garcia-Benito, R.; Husemann, B.; Mast, D.; Kehrig, C.; Iglesias-Paramo, J.; Marino, R. A.; Aguerri, J. A. L.; Walcher, C. J.; Vilchez, J. M.; Bomans, D. J.; Cortijo-Ferrero, C.; Gonzalez Delgado, R. M.; Bland-Hawthorn, J.; McIntosh, D. H.; Bekeraite, S.; CALIFA Collaboration</p> <p>2016-01-01</p> <p>The sample presented in this work was selected from 256 objects observed until March 20131. These galaxies are part of the CALIFA mother sample (hereafter CALIFA MS). We consider as objects in pairs those galaxies with companions within a projected distance of 160kpc, systemic velocity difference smaller than 300km/s, and a difference in r-band magnitude smaller than 2mag (relative distances, systemic velocities, and magnitudes were taken from NED3). Observations were carried out using the PPAK instrument at Calar Alto Observatory. Its main component consists of 331 fibers of 2.7" diameter each, concentrated in a single hexagon bundle covering a FoV of 74"x64", with a filling factor of ~60%. Three dithering pointings are taken for each object to reach a filling factor of 100% across the entire FoV (see details in Husemann et al. 2013). The final data cube consists of more than 4000 spectra at a sampling of 1"x1" per spaxel. (4 data files).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=victorian&pg=4&id=EJ1020415','ERIC'); return false;" href="http://eric.ed.gov/?q=victorian&pg=4&id=EJ1020415"><span>The (<span class="hlt">Mis</span>)Identification of Ineffective Classroom Teaching Practice: Critical Interrogations of Classroom Teacher Effectiveness Research</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Skourdoumbis, Andrew</p> <p>2013-01-01</p> <p>This paper critiques specific forms of classroom teacher effectiveness research. In doing so, the paper suggests that education policy-making deems and employs teacher effectiveness research as a promising and capable contrivance for the identification of ineffective classroom teaching practice. The paper engages with this policy debate by using a…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22139047','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22139047"><span>Parental weight (<span class="hlt">mis</span>)perceptions: factors influencing parents' ability to correctly categorise their child's weight status.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hudson, Eibhlin; McGloin, Aileen; McConnon, Aine</p> <p>2012-12-01</p> <p>This study investigates parents' ability to correctly classify their child's weight status. The influence of parent and child socio-demographic and lifestyle factors on parental misclassification of their child's weight status is explored. A representative sample of Irish children (aged 5-12 (n = 596) years, aged 13-17 years (n = 441)) and their parents (n = 1885) were recruited to participate in a national dietary survey. Parental perceptions of their child's weight and their own weight were measured. Anthropometric measurements (weight and height) were objectively measured for parents and children. Body Mass Index (BMI) scores were derived and categorised as normal, overweight or obese using standard references. Over 80% of parents of overweight boys and 79.3% of parents of overweight girls reported their child's weight was fine for his/her height and age. Furthermore, 44.4% of parents of obese boys and 45.3% of parents of obese girls felt their child's weight was fine for their height and age. Parents were significantly less likely to be correct about their sons' weight status and more likely to be correct the older the child. Parents were over 86% less likely to be correct about their child's weight if their child was overweight and approximately 59% less likely to be correct if the child was obese, compared to parents of normal weight children. This research suggests that parents are failing to recognise overweight and obesity in their children with factors such as parental weight status, child's age and gender influencing this.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4845824','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4845824"><span>(<span class="hlt">Mis</span>)use of Prescribed Stimulants in the Medical Student Community: Motives and Behaviors</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Fond, Guillaume; Gavaret, Martine; Vidal, Christophe; Brunel, Lore; Riveline, Jean-Pierre; Micoulaud-Franchi, Jean-Arthur; Domenech, Philippe</p> <p>2016-01-01</p> <p>Abstract The aim of this study was to estimate the prevalence of psychostimulant use in the French medical community and their motives. A population-based cross-sectional study using a self-administered online survey was done. A total of 1718 French students and physicians (mean age, 26.84±7.19 years, 37.1% men) were included. Self-reported lifetime use, motives, socio-demographic and academic features for over the counter (OTC), medically prescribed (MPP), and illicit (IP) psychostimulant users were reported. Lifetime prevalence of psychostimulant use was 33% (29.7% for OTC, 6.7% for MPP, and 5.2% for IP). OTC consumption mainly aimed at increasing academic performance and wakefulness during competitive exams preparation. OTC consumption started early and was predictive of later MPP use. Corticoids were the most frequently consumed MPP (4.5%) before methylphenidate and modafinil. Motives for MPP consumption were increased academic performance, concentration, memory, and wakefulness. Psychostimulant use is common among French medical community. Our results suggest that restrictions on methylphenidate and modafinil prescriptions are effective at limiting their use. However, these restrictions may explain the observed rates of corticoids consumption, which raise a new public health problem, given that corticoids may have severe side effects. PMID:27100420</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007QSRv...26.3081U','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007QSRv...26.3081U"><span><span class="hlt">MIS</span> 3 mammoth remains from Sweden—implications for faunal history, palaeoclimate and glaciation chronology</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Ukkonen, P.; Arppe, L.; Houmark-Nielsen, M.; Kjær, K. H.; Karhu, J. A.</p> <p>2007-12-01</p> <p>The distribution of low-arctic megafaunal remains in time and space from the area previously covered by the Scandinavian Ice Sheet (SIS) suggests the presence of breeding mammoth populations in the circum-Baltic region during the time interval from 44 to 26 ka ago. The transport history of 30 mammoth teeth and bones from southern and north-central Sweden was estimated and the remains were subjected to osteological analyses and 14C dating. Oxygen isotope analyses of tooth enamel indicate a palaeoclimate considerably more homogenous than that experienced in Sweden today, showing moderate north-south gradients in the δ18O value of precipitation and temperature. In general, the results support the model of restricted ice sheet distribution during the second half of the Middle Weichselian. The clear discrepancy in the inferred absence of glaciation in the central Swedish uplands and the Baltic basin as evidenced by the Swedish mammoth data versus the Danish OSL-based glaciation chronology in the period from 40 to 30 ka ago is discussed in the light of radiocarbon calibration and glacial dynamics.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013AGUFMPP21C1926P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013AGUFMPP21C1926P"><span>Propagation of the <span class="hlt">MIS</span>4 Eurasian Meltwater Event in the Arctic Ocean</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Polyak, L. V.; Spielhagen, R. F.; Norgaard-Pedersen, N.; Curry, W. B.</p> <p>2013-12-01</p> <p>Sediment records from the Arctic Ocean indicate multiple Pleistocene meltwater events from Eurasian and North American ice sheets. These events may have affected both the Arctic climate and the North Atlantic deep-water formation, and are important for understanding the stability of Pleistocene ice sheets. We investigate the distribution of meltwater during the discharge of large Eurasian proglacial lakes at the end of Marine Isotope Stage 4, approximately 50-60 ka, using stable isotope records in planktic and benthic foraminifers. Studies focused on lithological and radiogenic isotope proxies suggest that this meltwater pulse affected sedimentation in the Eurasian Basin all the way to the Lomonosov Ridge and at least part of the Amerasian Basin (Mendeleev Ridge). The analysis of stable-isotope data provides further insights. The spatial distribution of planktonic oxygen-18, with the lightest values in the Mendeleev Ridge area, reveals a strong cyclonic circulation extending into the western Arctic Ocean, similar to the negative Arctic Oscillation mode. This circulation pattern differs from that inferred from lithostratigraphy and neodymium isotopes indicating a stronger effect of Eurasian discharge on the Lomonosov Ridge. We propose that this discrepancy resulted from a decoupling of surface and deep-water circulation, where deep waters had a significant contribution of brines carrying deglacial sediments (hyperpicnal flows). The propagation of proglacial brines as far as the Amerasian Basin, suggested earlier from neodymium isotope data, is confirmed by benthic stable isotope records.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA447589','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA447589"><span>The History of <span class="hlt">MIS</span>-Y: U.S. Strategic Interrogation During World War II</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2002-08-01</p> <p>intelligence; HUMINT; U.S. Army Field Manual 34-52; Hanns Scharff; Camp 020; Military Intelligence Service; MI9; MI19; Director of Military...of actionable intelligence. This is reflected in modern U.S. doctrine pertaining to interrogation as defined in U.S. Army Field Manual 34-52...15As quoted in Jones, 60-61. 16Department of the Army, Field Manual 34-52, Intelligence Interrogation (Washington, DC: GPO, 8 May 1987), 1-0</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12622226','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12622226"><span>The <span class="hlt">mis</span>-identification of the major antioxidant flavonoids in young barley (Hordeum vulgare) leaves.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Markham, Kenneth R; Mitchell, Kevin A</p> <p>2003-01-01</p> <p>Several papers have appeared in the literature since 1992 which refer to a major "isoflavonoid" antioxidant in young green barley leaves (Hordeum vulgare) as 2''-O-glucosylisovitexin. In the present paper the original NMR data supporting this structural assignment are examined and found to have been misinterpreted. HPLC and NMR data are used to prove that the major flavonoid antioxidants in young green barley leaves are in fact the flavone-C-glycosides, saponarin and lutonarin.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=alberts&pg=6&id=EJ1021305','ERIC'); return false;" href="http://eric.ed.gov/?q=alberts&pg=6&id=EJ1021305"><span>Education and the Face of the Other: Levinas, Camus and (<span class="hlt">Mis</span>)Understanding</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Roberts, Peter</p> <p>2013-01-01</p> <p>Among the most neglected of Albert Camus' literary works is his play "The misunderstanding." Composed while Camus was in exile in occupied France, and first performed on stage in 1944, "The misunderstanding" depicts the events that unfold when a man returns, without declaring his identity, to a home he left 20 years ago.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016QSRv..131...51K','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016QSRv..131...51K"><span>Isotopic variability of cave bears (δ15N, δ13C) across Europe during <span class="hlt">MIS</span> 3</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Krajcarz, Magdalena; Pacher, Martina; Krajcarz, Maciej T.; Laughlan, Lana; Rabeder, Gernot; Sabol, Martin; Wojtal, Piotr; Bocherens, Hervé</p> <p>2016-01-01</p> <p>Collagen, the organic fraction of bone, records the isotopic parameters of consumed food for carbon (δ13C) and nitrogen (δ15N). This relationship of isotopic signature between diet and tissue is an important tool for the study of dietary preferences of modern and fossil animal species. Since the first information on the isotopic signature of cave bear was reported, numerous data from Europe have become available. The goal of this work is to track the geographical variation of cave bear collagen isotopic values in Europe during Marine Isotopic Stage 3 (about 60,000-25,000 yr BP). In this study the results of new δ13C and δ15N isotopic analyses of cave bear collagen from four Central-Eastern European sites are presented, as well as a review of all published isotopic data for cave bears of the same period. The main conclusion is a lack of geographical East-West pattern in the variations of δ13C and δ15N values of cave bear collagen. Moreover, no relationship was found between cave bear taxonomy and isotopic composition. The cave bears from Central-Eastern Europe exhibit δ13C and δ15N values near the average of the range of Central, Western and Southern European cave bears. Despite the fact that most cave bear sites follow an altitudinal gradient, separate groups of sites exhibit shift in absolute values of δ13C, what disturbs an altitude-related isotopic pattern. The most distinct groups are: high Alpine sites situated over 1500 m a.s.l. - in terms of δ13C; and two Romanian sites Peştera cu Oase and Urşilor - in case of δ15N. Although the cave bear isotopic signature is driven by altitude, the altitudinal adjustment of isotopic data is not enough to explain the isotopic dissimilarity of these cave bears. The unusually high δ15N signature of mentioned Romanian sites is an isolated case in Europe. Cave bears from relatively closely situated Central-Eastern European sites and other Romanian sites are more similar to Western European than to Romanian populations in terms of isotopic composition, and probably ecology.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014sf2a.conf..217C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014sf2a.conf..217C"><span>Spin-Orbit angle distribution and the origin of (<span class="hlt">mis</span>)aligned hot Jupiters</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Crida, A.; Batygin, K.</p> <p>2014-12-01</p> <p>The angle between the orbital plane and the stellar equator (called the spin-orbit angle) has been measured for about 60 hot Jupiters, half of them showing significant misalignment. This challenges scenarios of the formation of hot Jupiters. Recently, it has been proposed that misalignment could be a consequence of the torquing of the proto-planetary disk by a transcient binary companion of the host star Here, we analyse the geometry of the problem, and compare the probability density function (PDF) of the projected spin-orbit angle expected in various mechanisms, with the observed one. Scattering models and the Kozai cycle with tidal friction models can not be solely responsible for the production of all hot Jupiters. Conversely, the presently observed distribution of the spin-orbit angles is compatible with most hot Jupiters having been transported by smooth migration inside a proto-planetary disk, itself possibly torqued by a companion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014A%26A...567A..42C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014A%26A...567A..42C"><span>Spin-orbit angle distribution and the origin of (<span class="hlt">mis</span>)aligned hot Jupiters</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Crida, A.; Batygin, K.</p> <p>2014-07-01</p> <p>Context. For 61 transiting hot Jupiters, the projection of the angle between the orbital plane and the stellar equator (called the spin-orbit angle) has been measured. For about half of them, a significant misalignment is detected, and retrograde planets have been observed. This challenges scenarios of the formation of hot Jupiters. Aims: In order to better constrain formation models, we relate the distribution of the real spin-orbit angle Ψ to the projected one β. Then, a comparison with the observations is relevant. Methods: We analyse the geometry of the problem to link analytically the projected angle β to the real spin-orbit angle Ψ. The distribution of Ψ expected in various models is taken from the literature, or derived with a simplified model and Monte Carlo simulations in the case of the disk-torquing mechanism. Results: An easy formula to compute the probability density function (PDF) of β knowing the PDF of Ψ is provided. All models tested here look compatible with the observed distribution beyond 40 degrees, which is so far poorly constrained by only 18 observations. But only the disk-torquing mechanism can account for the excess of aligned hot Jupiters, provided that the torquing is not always efficient. This is the case if the exciting binaries have semi-major axes as large as ~104 AU. Conclusions: Based on comparison with the set of observations available today, scattering models and the Kozai cycle with tidal friction models can not be solely responsible for the production of all hot Jupiters. Conversely, the presently observed distribution of the spin-orbit angles is compatible with most hot Jupiters having been transported by smooth migration inside a proto-planetary disk, itself possibly torqued by a companion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015MEdRJ..27..233Z','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015MEdRJ..27..233Z"><span>Conceptual <span class="hlt">mis</span>(understandings) of fractions: From area models to multiple embodiments</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Zhang, Xiaofen; Clements, M. A. (Ken); Ellerton, Nerida F.</p> <p>2015-06-01</p> <p>Area-model representations seem to have been dominant in the teaching and learning of fractions, especially in primary school mathematics curricula. In this study, we investigated 40 fifth grade children's understandings of the unit fractions, , and , represented through a variety of different models. Analyses of pre-teaching test and interview data revealed that although the participants were adept at partitioning regional models, they did not cope well with questions for which unit fractions were embodied in non-area-model scenarios. Analyses of post-teaching test and interview data indicated that after their participation in an instructional intervention designed according to Dienes' (1960) dynamic principle, the students' performances on tests improved significantly, and their conceptual understandings of unit fractions developed to the point where they could provide reasonable explanations of how they arrived at solutions. Analysis of retention data, gathered more than 3 months after the teaching intervention, showed that the students' newly found understandings had, in most cases, been retained.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010SPIE.7732E..1OA','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010SPIE.7732E..1OA"><span><span class="hlt">MIS</span> μ-calorimeters arrays: an alternative to IXO/XMS TES/Squids baseline</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Aliane, Abdelkader; Sauvageot, J. L.; de La Broïse, X.; Pigot, C.; Martignac, J.; Grémion, E.; Szeflinski, V.; Goupy, J.; Agnese, P.</p> <p>2010-07-01</p> <p>The IXO/XMS instrument baseline is an array of TES sensors. Alternatively, we are now developing a μ- calorimeter array based on Silicon doped sensors. Our strength stands in a very low power consumption at 50 mK, allowing more than 4000 readout channels in the limited power budget of the IXO/XMS cryostat, for a Field of View as large as 6'x6' square while keeping the same spectral resolution. In parallel, we develop the cold (2-4K) frontend electronics based on High Electron Mobility Transistors (GaAlAs/GaAs) and SiGe ASIC electronics to readout, amplify and multiplex the signals. We present the status of our development and our current design study.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26538767','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26538767"><span>Teacher (<span class="hlt">Mis</span>)Perceptions of Preschoolers' Academic Skills: Predictors and Associations With Longitudinal Outcomes.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Baker, Courtney N; Tichovolsky, Marianne H; Kupersmidt, Janis B; Voegler-Lee, Mary Ellen; Arnold, David H</p> <p>2015-08-01</p> <p>Preschool teachers have important impacts on children's academic outcomes, and teachers' misperceptions of children's academic skills could have negative consequences, particularly for low-income preschoolers. This study utilized data gathered from 123 preschool teachers and their 760 preschoolers from 70 low-income, racially diverse centers. Hierarchical linear modeling was utilized to account for the nested data structure. Even after controlling for children's actual academic skill, older children, children with stronger social skills, and children with fewer inattentive symptoms were perceived to have stronger academic abilities. Contrary to hypotheses, preschoolers with more behavior problems were perceived by teachers to have significantly better pre-academic abilities than they actually had. Teachers' perceptions were not associated with child gender or child race/ethnicity. Although considerable variability was due to teacher-level characteristics, child characteristics explained 42% of the variability in teachers' perceptions about children's language and pre-literacy ability and 41% of the variability in teachers' perceptions about mathability. Notably, these perceptions appear to have important impacts over time. Controlling for child baseline academic skill and child characteristics, teacher perceptions early in the preschool year were significantly associated with child academic outcomes during the spring for both language and pre-literacy and math. Study implications with regard to the achievement gap are discussed.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=error+AND+reasoning+AND+Mathematics&pg=4&id=EJ847631','ERIC'); return false;" href="http://eric.ed.gov/?q=error+AND+reasoning+AND+Mathematics&pg=4&id=EJ847631"><span>The Effects and Side-Effects of Statistics Education: Psychology Students' (<span class="hlt">Mis</span>-)Conceptions of Probability</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Morsanyi, Kinga; Primi, Caterina; Chiesi, Francesca; Handley, Simon</p> <p>2009-01-01</p> <p>In three studies we looked at two typical misconceptions of probability: the representativeness heuristic, and the equiprobability bias. The literature on statistics education predicts that some typical errors and biases (e.g., the equiprobability bias) increase with education, whereas others decrease. This is in contrast with reasoning theorists'…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15789154','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15789154"><span>(<span class="hlt">Mis</span>)alignments in counseling for Huntington's Disease predictive testing: clients' responses to reflective frames.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sarangi, Srikant; Bennert, Kristina; Howell, Lucy; Clarke, Angus; Harper, Peter; Gray, Jonathon</p> <p>2005-02-01</p> <p>As a sequel to an earlier paper (Sarangi et al., 2004. J Genet Couns, 13(2), 135-155) examining genetic counselors' initiation of reflective frames, in this paper we analyze the variable ways in which clients respond to such reflective frames in the clinical setting. Of the six types of reflective questions identified, we focus on two types, which recur throughout the counseling protocol: (i) questions about clients' decisions to have genetic testing and (ii) questions exploring the potential impact of a positive or negative test result. The analytic focus here is on the mismatches surrounding clients' apparent readiness to discuss coping with the onset of disease (risk of disease) when they have been asked to discuss coping with genetic test results (risk of knowing). Our theoretical discussion is centered around the notion of alignment as a framework for locating the convergence and divergence of counselors' and clients' agendas in interaction. Drawing on detailed transcripts of 24 Huntington's Disease counseling consultations in South Wales, we analyze 119 counselor-client question-response sequences using the methodology of discourse analysis. Preliminary coding of clients' responses led us to identify three recurrent themes: (a) gaining knowledge as a basis for future action; (b) needing to know as a subjective necessity; and (c) downplaying what can be known. In a further analysis of extended data extracts, we draw attention to how clients display varying degrees of engagement with regard to the testing process and outcomes along the temporal and social axes. At one extreme, clients may take up the opportunity to engage in self-reflection, and thus endorse the legitimacy of the reflective frame. At the other extreme, clients may implicitly or explicitly challenge the relevance of self-reflection, and hence the usefulness of this counselor-initiated routine. We suggest that clients' varied response behaviors result from the perceived need of some clients to display their 'readiness' for predictive testing-an overarching 'meta-question' posed by the very existence of the counseling protocol.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/12466560','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/12466560"><span>Monitoring <span class="hlt">mis</span>-acylated tRNA suppression efficiency in mammalian cells via EGFP fluorescence recovery.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ilegems, Erwin; Pick, Horst M; Vogel, Horst</p> <p>2002-12-01</p> <p>A reporter assay was developed to detect and quantify nonsense codon suppression by chemically aminoacylated tRNAs in mammalian cells. It is based on the cellular expression of the enhanced green fluorescent protein (EGFP) as a reporter for the site-specific amino acid incorporation in its sequence using an orthogonal suppressor tRNA derived from Escherichia coli. Suppression of an engineered amber codon at position 64 in the EGFP run-off transcript could be achieved by the incorporation of a leucine via an in vitro aminoacylated suppressor tRNA. Microinjection of defined amounts of mutagenized EGFP mRNA and suppressor tRNA into individual cells allowed us to accurately determine suppression efficiencies by measuring the EGFP fluorescence intensity in individual cells using laser-scanning confocal microscopy. Control experiments showed the absence of natural suppression or aminoacylation of the synthetic tRNA by endogenous aminoacyl-tRNA synthetases. This reporter assay opens the way for the optimization of essential experimental parameters for expanding the scope of the suppressor tRNA technology to different cell types.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_18");'>18</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li class="active"><span>20</span></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_20 --> <div id="page_21" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="401"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=%22management+information+system%22&pg=2&id=EJ922441','ERIC'); return false;" href="http://eric.ed.gov/?q=%22management+information+system%22&pg=2&id=EJ922441"><span>Teaching Higher Order Thinking in the Introductory <span class="hlt">MIS</span> Course: A Model-Directed Approach</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Wang, Shouhong; Wang, Hai</p> <p>2011-01-01</p> <p>One vision of education evolution is to change the modes of thinking of students. Critical thinking, design thinking, and system thinking are higher order thinking paradigms that are specifically pertinent to business education. A model-directed approach to teaching and learning higher order thinking is proposed. An example of application of the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=60632&keyword=phase+AND+noise&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=89845568&CFTOKEN=11740604','EPA-EIMS'); return false;" href="http://cfpub.epa.gov/si/si_public_record_report.cfm?dirEntryId=60632&keyword=phase+AND+noise&actType=&TIMSType=+&TIMSSubTypeID=&DEID=&epaNumber=&ntisID=&archiveStatus=Both&ombCat=Any&dateBeginCreated=&dateEndCreated=&dateBeginPublishedPresented=&dateEndPublishedPresented=&dateBeginUpdated=&dateEndUpdated=&dateBeginCompleted=&dateEndCompleted=&personID=&role=Any&journalID=&publisherID=&sortBy=revisionDate&count=50&CFID=89845568&CFTOKEN=11740604"><span>MALDI-<span class="hlt">MIS</span> INVESTIGATIONS OF DRINKING WATER PATHOGENS--GIARDIA AND CRYPTOSPORIDIUM</span></a></p> <p><a target="_blank" href="http://oaspub.epa.gov/eims/query.page">EPA Science Inventory</a></p> <p></p> <p></p> <p>The protozoan parasites, Cryptosporidium parvum and Giardia lamblia, have been responsible for numerous waterborne outbreaks of gastrointestinal illness in the United States. The 1993 cryptosporidiosis outbreak in Milwaukee affected approximately 400,000 people and resulted in o...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26087060','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26087060"><span>Protein <span class="hlt">Mis</span>-Termination Initiates Genetic Diseases, Cancers, and Restricts Bacterial Genome Expansion.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Wong, Tit-Yee; Schwartzbach, Steve D</p> <p>2015-01-01</p> <p>Protein termination is an important cellular process. Protein termination relies on the stop-codons in the mRNA interacting properly with the releasing factors on the ribosome. One third of inherited diseases, including cancers, are associated with the mutation of the stop-codons. Many pathogens and viruses are able to manipulate their stop-codons to express their virulence. The influence of stop-codons is not limited to the primary reading frame of the genes. Stop-codons in the second and third reading frames are referred as premature stop signals (PSC). Stop-codons and PSCs together are collectively referred as stop-signals. The ratios of the stop-signals (referred as translation stop-signals ratio or TSSR) of genetically related bacteria, despite their great differences in gene contents, are much alike. This nearly identical Genomic-TSSR value of genetically related bacteria may suggest that bacterial genome expansion is limited by their unique stop-signals bias. We review the protein termination process and the different types of stop-codon mutation in plants, animals, microbes, and viruses, with special emphasis on the role of PSCs in directing bacterial evolution in their natural environments. Knowing the limit of genomic boundary could facilitate the formulation of new strategies in controlling the spread of diseases and combat antibiotic-resistant bacteria.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=learning+AND+fractions&pg=4&id=EJ1059859','ERIC'); return false;" href="http://eric.ed.gov/?q=learning+AND+fractions&pg=4&id=EJ1059859"><span>Conceptual <span class="hlt">Mis</span>(understandings) of Fractions: From Area Models to Multiple Embodiments</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Zhang, Xiaofen; Clements, M. A.; Ellerton, Nerida F.</p> <p>2015-01-01</p> <p>Area-model representations seem to have been dominant in the teaching and learning of fractions, especially in primary school mathematics curricula. In this study, we investigated 40 fifth grade children's understandings of the unit fractions, 1/2, 1/3, and 1/4, represented through a variety of different models. Analyses of pre-teaching test and…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=racism&pg=4&id=EJ940678','ERIC'); return false;" href="http://eric.ed.gov/?q=racism&pg=4&id=EJ940678"><span>The Four Personae of Racism: Educators' (<span class="hlt">Mis</span>)Understanding of Individual vs. Systemic Racism</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Young, Evelyn Y.</p> <p>2011-01-01</p> <p>This study used CRT to engage educators in critical discourse regarding the persistence of racism in urban schooling. A combined method of action research and critical case study was employed to raise a group of educators' race consciousness through antiracist training. Findings revealed conflicting views of racism as an individual pathology vs. a…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=grade+AND+inflation&pg=6&id=EJ796511','ERIC'); return false;" href="http://eric.ed.gov/?q=grade+AND+inflation&pg=6&id=EJ796511"><span>Management by Results: Student Evaluation of Faculty Teaching and the <span class="hlt">Mis</span>-Measurement of Performance</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Langbein, Laura</p> <p>2008-01-01</p> <p>Using data on 4 years of courses at American University, regression results show that actual grades have a significant, positive effect on student evaluations of teaching (SETs), controlling for expected grade and fixed effects for both faculty and courses, and for possible endogeneity. Implications are that the SET is a faulty measure of teaching…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=millennials&pg=2&id=EJ1041109','ERIC'); return false;" href="http://eric.ed.gov/?q=millennials&pg=2&id=EJ1041109"><span>Off Our Lawns and out of Our Basements: How We (<span class="hlt">Mis</span>)Understand the Millennial Generation</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Mechler, Heather</p> <p>2013-01-01</p> <p>In this article, the author explores the existing research on the characteristics of Millennials within historical, social, and economic contexts. While many researchers have made claims about Millennials, they fail to consider how parenting styles, economic factors, historical events, and shifts in educational priorities may have created the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015EGUGA..1713404B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015EGUGA..1713404B"><span>ELSA flood stack for <span class="hlt">MIS</span> 2-3 from dry maar lakestructure Auel (Eifel/Germany)</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Brunck, Heiko; Sirocko, Frank</p> <p>2015-04-01</p> <p>Lacustrine sediments are very sensitive to natural and anthropogenically enviromental changes. Thus, lake sediments are excellent climate archives and can be used for reconstructions of past precipitation and flood events. However, until now, there is no continous flood record for the entire last 60 000 years for Central Europe. The present study reconstructs paleo floods from event layers in the sediment, of dry maar lakestructure Auel (Eifel). This silted up basin has an inflow by a local stream. Accordingly the sedimentation rate is directly linked to runoff activity. The bioturbation was low so that event layers become visible, but varves are not preserved. The maar site is near to the town of Gerolstein in the Eifel; the core AU2 was drilled in the ELSA (Eifel Laminated Sediment archive) project and is 123m long. AU2 has the highest sedimentation rate of all ELSA cores, due to abundant fluvial input. The Eifel area is well suited to approximate Central European weather, because modern water level gauge data from Eifel rivers correlate with respective data from the Rhine (Wernli and Pfahl, 2009). Due to the high inflow into the maar, Auel has the highest number of botanical macro remains of all ELSA cores. These specific conditions explain why only in AU2 all 21 Greenland interstadials can be observed in the abundance of wood remains and the organic carbon concentration. In a final stratigraphic step the time series of Corg was tuned to the Greenland ice core chronology to link the central European landscape evolution directly to the Greenland climate curve (Svensson et al., 2008). Combined sedimentological, paleobotanical and geochemical data received from AU2 builds the foundation of the 14C based chronology. The synchronisation of the record with other cores is controlled by tephra time markers and pollen. Both are used to align the main cores of the ELSA project and construct an integrated age model for the last 220 000 years [b2k] (Förster and Sirocko, 2014). To study the past flood events in detail, 10 cm long thin sections were analyzed to distinguish flood layers from distal turbidites. Turbidites have a continuous grain size gradation; the grains size profile of flood events is in contrast characterized by several grain size maxima over the entire layer thickness. A flood event over several days shows numerous peaks of intense discharge, which lead to a discontinuous grain size gradient. The thickness of each flood layer was measured for the classification of the event intensity. As a consequence, 88 flood layers over 7.5 mm thickness were detected. Our time-series represents the first highly-resolved chronology for flood events from 60 000 years until present times and indicates variable periodicities of flood activity linked to predominant climatic development. The fore main sections of all flood layers are: 44 000 - 45 500, 30 000 - 37 000, 20 000 - 22 500 and 11 000 - 17 000 years [b2k].</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=people+AND+sex&pg=6&id=EJ803385','ERIC'); return false;" href="http://eric.ed.gov/?q=people+AND+sex&pg=6&id=EJ803385"><span>Teenage Pregnancy and Sex and Relationship Education: Myths and (<span class="hlt">Mis</span>)conceptions</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Vincent, Kerry</p> <p>2007-01-01</p> <p>This paper explores the role of sex and relationship education (SRE) in reducing teenage pregnancy rates. It critically examines some of the assumptions underlying the emphasis placed on SRE within the teenage pregnancy strategy ( SEU, 1999)--in particular, the view that ignorance of sexual matters plays a key part in teenage conception. An…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20205420','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20205420"><span>DNA scissors device used to measure MutS binding to DNA <span class="hlt">mis</span>-pairs.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Gu, Hongzhou; Yang, Wei; Seeman, Nadrian C</p> <p>2010-03-31</p> <p>MutS is a DNA repair protein that recognizes unpaired and bulged bases. When it binds to DNA, it bends the double helix. We have developed a novel DNA-based nanomechanical device that measures the amount of work that a DNA-bending protein can do when it binds to the double helix. The device we report here is a scissors-like device consisting of two double-crossover (DX) molecules connected to each other by a flexible Holliday junction. The two DX components are connected by a double helix that contains the binding site for MutS; when the binding site duplex is bent, the scissors contracts. The two DX molecules are also joined by sticky ends on an edge adjacent to the binding site; the sticky ends can be disrupted if the protein binds with sufficient free energy. Those sticky ends are flanked by a pair of dyes; when the sticky ends are disrupted, the dyes separate, and the fluorescence resonance energy transfer signal can monitor the disruption. The strength of the sticky ends is readily varied, so that the ability of the protein to disrupt them can be quantitated. We use this device to measure work in conjunction with a second device that measures the bending angle resulting from protein binding, so as to calibrate the system. Our data are in good agreement with previous measurements of MutS binding, indicating that this device is able to measure the strength of binding correctly.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21926337','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21926337"><span><span class="hlt">Mis</span>-sizing of stent promotes intimal hyperplasia: impact of endothelial shear and intramural stress.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Chen, Henry Y; Sinha, Anjan K; Choy, Jenny S; Zheng, Hai; Sturek, Michael; Bigelow, Brian; Bhatt, Deepak L; Kassab, Ghassan S</p> <p>2011-12-01</p> <p>Stent can cause flow disturbances on the endothelium and compliance mismatch and increased stress on the vessel wall. These effects can cause low wall shear stress (WSS), high wall shear stress gradient (WSSG), oscillatory shear index (OSI), and circumferential wall stress (CWS), which may promote neointimal hyperplasia (IH). The hypothesis is that stent-induced abnormal fluid and solid mechanics contribute to IH. To vary the range of WSS, WSSG, OSI, and CWS, we intentionally mismatched the size of stents to that of the vessel lumen. Stents were implanted in coronary arteries of 10 swine. Intravascular ultrasound (IVUS) was used to size the coronary arteries and stents. After 4 wk of stent implantation, IVUS was performed again to determine the extent of IH. In conjunction, computational models of actual stents, the artery, and non-Newtonian blood were created in a computer simulation to yield the distribution of WSS, WSSG, OSI, and CWS in the stented vessel wall. An inverse relation (R(2) = 0.59, P < 0.005) between WSS and IH was found based on a linear regression analysis. Linear relations between WSSG, OSI, and IH were observed (R(2) = 0.48 and 0.50, respectively, P < 0.005). A linear relation (R(2) = 0.58, P < 0.005) between CWS and IH was also found. More statistically significant linear relations between the ratio of CWS to WSS (CWS/WSS), the products CWS × WSSG and CWS × OSI, and IH were observed (R(2) = 0.67, 0.54, and 0.56, respectively, P < 0.005), suggesting that both fluid and solid mechanics influence the extent of IH. Stents create endothelial flow disturbances and intramural wall stress concentrations, which correlate with the extent of IH formation, and these effects were exaggerated with mismatch of stent/vessel size. These findings reveal the importance of reliable vessel and stent sizing to improve the mechanics on the vessel wall and minimize IH.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2654172','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2654172"><span>Are phonological influences on lexical (<span class="hlt">mis</span>)selection the result of a monitoring bias?</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Ratinckx, Elie; Ferreira, Victor S.; Hartsuiker, Robert J.</p> <p>2009-01-01</p> <p>A monitoring bias account is often used to explain speech error patterns that seem to be the result of an interactive language production system, like phonological influences on lexical selection errors. A biased monitor is suggested to detect and covertly correct certain errors more often than others. For instance, this account predicts that errors which are phonologically similar to intended words are harder to detect than ones that are phonologically dissimilar. To test this, we tried to elicit phonological errors under the same conditions that show other kinds of lexical selection errors. In five experiments, we presented participants with high cloze probability sentence fragments followed by a picture that was either semantically related, a homophone of a semantically related word, or phonologically related to the (implicit) last word of the sentence. All experiments elicited semantic completions or homophones of semantic completions, but none elicited phonological completions. This finding is hard to reconcile with a monitoring bias account and is better explained with an interactive production system. Additionally, this finding constrains the amount of bottom-up information flow in interactive models. PMID:18942035</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=insomnia&id=EJ962990','ERIC'); return false;" href="http://eric.ed.gov/?q=insomnia&id=EJ962990"><span>(<span class="hlt">Mis</span>)perception of Sleep in Insomnia: A Puzzle and a Resolution</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Harvey, Allison G.; Tang, Nicole K. Y.</p> <p>2012-01-01</p> <p>Insomnia is prevalent, causing severe distress and impairment. This review focuses on illuminating the puzzling finding that many insomnia patients misperceive their sleep. They overestimate their sleep onset latency (SOL) and underestimate their total sleep time (TST), relative to objective measures. This tendency is ubiquitous (although not…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=cigarettes&pg=7&id=EJ1095862','ERIC'); return false;" href="http://eric.ed.gov/?q=cigarettes&pg=7&id=EJ1095862"><span>Adolescent (<span class="hlt">Mis</span>)Perceptions about Nicotine Addiction: Results from a Mixed-Methods Study</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Roditis, Maria; Lee, Joann; Halpern-Felsher, Bonnie L.</p> <p>2016-01-01</p> <p>Purpose: Despite evidence that adolescents become addicted to nicotine even after limited use, adolescents believe they can experiment with or smoke cigarettes for a few years and easily quit. The goal of this study was to examine adolescents' understanding of the definition and process of nicotine addiction using a mixed-methods approach. Method:…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1109663.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1109663.pdf"><span>The Relationship among Creative (<span class="hlt">Mis</span>) Fit, College Culture, Creative and Academic Self-Efficacy</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Cayirdag, Nur</p> <p>2016-01-01</p> <p>Although person-environment fit (PEF) has been extensively studied in organizational psychology and business literature, its application to educational context has been limited. The current study used PEF framework in terms of creativity within the context of higher education. The nature of relationship between person-environment fit, college…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=put&pg=4&id=EJ1039916','ERIC'); return false;" href="http://eric.ed.gov/?q=put&pg=4&id=EJ1039916"><span>The Spiral of Science (<span class="hlt">Mis</span>)Education, Parker's "Multiple Influences," and Missed Opportunities</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Richardson Bruna, Katherine</p> <p>2014-01-01</p> <p>In this reflection on Carolyn Parker's article, I connect to my own professional work at the intersection of Latino education and science education as well as to my own personal interest in liberation theology. I use constructs central to liberation theology to indicate what a liberationist science might look like and push us, in doing so, to…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA481999','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA481999"><span>Ultra-Fast Image Sensor Using Ge on Insulator <span class="hlt">MIS</span>/Schottky Detectors</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2008-05-28</p> <p>Appl . Phys. Lett., vol. 80, no. 5, pp. 793-795, Feb. 2002. [5] S. M. Sze, Physics of Semiconductor Devices (2nd Edition). Taipei, Taiwan, R.O.C., 1985...type Si and Ge,” Appl . Phys. Lett., vol. 88, no. 14, p. 143509, Apr. 2006. [12] M. Heyns, M. Meuris, and M. Caymax, “Ge and III/V as enabling...Lin, C.-Y. Yu, C.-Y. Peng, W. S. Ho, and C. W. Liu, “Broadband SiGe/Si quantum dot infrared photodetectors,” J. Appl . Phys., Vol. 101, 033117, 2007</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA482660','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA482660"><span>The Role of Vitamin D Stimulation of Mullerian Inhibiting Substance (<span class="hlt">MIS</span>) in Prostate Cancer Therapy</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2007-12-01</p> <p>Interestingly, in one VDR knockout mouse model uterine hypoplasia with impaired folliculogenesis was found in female reproductive organs but not vitamin...uterine hypoplasia and growth retardation after weaning. Nat Genet 16:391-396 4. Malloy PJ, Pike JW, Feldman D 2005 Hereditary 1,25-dihydroxyvitamin D</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4547200','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4547200"><span>The <span class="hlt">mis</span>-measurement of extreme global poverty: A case study in the Pacific Islands</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Gubhaju, Bina</p> <p>2015-01-01</p> <p>Debate over the measurement of global poverty in low- and middle-income countries continues unabated. There is considerable controversy surrounding the ‘dollar a day’ measure used to monitor progress against the Millennium Development Goals. This article shines fresh light on the debate with new empirical analyses of poverty (including child poverty), inequality and deprivation levels in the Pacific island state of Vanuatu. The study focuses not only on economic and monetary metrics and measures, but also the measures of deprivation derived from sociology in relation to shelter, sanitation, water, information, nutrition, health and education. Until recently, there had been few, if any, attempts to study poverty and deprivation disparities among children in this part of the world. Different measures yield strikingly different estimates of poverty. The article, therefore, attempts to situate the study findings in the broader international context of poverty measurement and discusses their implications for future research and the post-2015 development agenda. PMID:26336359</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=impact+AND+media+AND+education&id=EJ1058282','ERIC'); return false;" href="http://eric.ed.gov/?q=impact+AND+media+AND+education&id=EJ1058282"><span><span class="hlt">Mis</span>/Representations in School-Based Digital Media Production: An Ethnographic Exploration with Muslim Girls</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Dahya, Negin; Jenson, Jennifer</p> <p>2015-01-01</p> <p>In this article, the authors discuss findings from a digital media production club with racialized girls in a low-income school in Toronto, Ontario. Specifically, the authors consider how student-produced media is impacted by ongoing postcolonial structures relating to power and representation in the school and in the media production work of…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_19");'>19</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li class="active"><span>21</span></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_21 --> <div id="page_22" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="421"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014CSSE....9..335R','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014CSSE....9..335R"><span>The spiral of science (<span class="hlt">mis</span>)education, Parker's ``multiple influences,'' and missed opportunities</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Richardson Bruna, Katherine</p> <p>2014-06-01</p> <p>In this reflection on Carolyn Parker's article, I connect to my own professional work at the intersection of Latino education and science education as well as to my own personal interest in liberation theology. I use constructs central to liberation theology to indicate what a liberationist science might look like and push us, in doing so, to put learning, not teaching, at the center of our efforts.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Chomsky%2c+AND+Noam&id=ED489025','ERIC'); return false;" href="http://eric.ed.gov/?q=Chomsky%2c+AND+Noam&id=ED489025"><span>Chomsky on <span class="hlt">Mis</span>Education. Critical Perspectives Series: A Book Series Dedicated to Paulo Freire</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Chomsky, Noam</p> <p>2004-01-01</p> <p>Noam Chomsky's prolific writings have made him one of the most-quoted educators in history--the only living writer on a most-cited list that includes Plato, Shakespeare, and Freud. Yet until now, no book has systematically offered Chomsky's influential writings on education. In this book, Noam Chomsky encourages a larger understanding of…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.osti.gov/scitech/biblio/5560743','SCIGOV-STC'); return false;" href="https://www.osti.gov/scitech/biblio/5560743"><span>Proposed operating strategy for a field <span class="hlt">mis</span> oil shale retorting experiment (RBOSC Retort O)</span></a></p> <p><a target="_blank" href="http://www.osti.gov/scitech">SciTech Connect</a></p> <p>Braun, R.L.; Campbell, J.H.; McKenzie, D.R.; Raley, J.H.; Gregg, M.L.</p> <p>1980-01-01</p> <p>A possible operating strategy for a field scale retort (similar to Retort 0) proposed by the Rio Blanco Oil Shale Company (RBOSC)) is discussed. This retorting strategy was developed based on model calculations, pilot retort experiments, and laboratory work carried out at LLL. From these calculations a set of operating conditions are derived that appear to give the best overall retort performance. A performance monitoring strategy is being developed based solely on the exit gas and oil composition.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA475714','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA475714"><span>Al-Qaida’s (<span class="hlt">Mis</span>)Adventures in the Horn of Africa</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2007-01-01</p> <p>anything. All the people there prefer to subsist off wheat and camel milk , and because of this, they are stingy and greedy. There are some stories so you...our way of life as a free and open society; and 2) The creation of a global environment inhospitable to violent extremists and all who support them...al-Qa’ida documents captured during operations in support of the Global War on Terror and maintained on the Department of Defense’s Harmony</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED083937.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED083937.pdf"><span>Financial Aid: Who Needs It? <span class="hlt">MIS</span> Research Profile, Volume One, Number 1, Mar. 1973.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Jackson, Linda M.</p> <p></p> <p>This report examines various aspects of financial aid including financial need as the basis for financial aid to students and the problem of inadequate funds. Recommendations suggest: (1) When forms are administered to the students, more guidance is needed to make them aware of the differences in the two systems presently serving the colleges and…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2014AGUFMPP21A1296D','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2014AGUFMPP21A1296D"><span>Linking Agulhas Leakage Variability and North Atlantic Climate <span class="hlt">MIS</span> 1-5a</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Dyez, K. A.; Zahn, R.; Hall, I. R.</p> <p>2014-12-01</p> <p>Agulhas leakage of warm, salty water from the Indian Ocean to the South Atlantic is suggested to have altered Atlantic meridional overturning and climate in the North Atlantic. One way to assess such linkages with North Atlantic climate variability is to examine the past Agulhas hydrography via high-resolution marine records from the Agulhas Bank slope. Here we present one such hydrographic estimate from the Agulhas Bank slope in the Atlantic sector of the Agulhas Corridor using planktic foraminiferal (Globigerinoides ruber) δ18O and Mg/Ca-derived SST to estimate surface salinity. By focusing on the last 80,000 years this is the first quantitative fine-scale Agulhas leakage record that overlaps in time with the Greenland ice core record of abrupt climate changes in the North Atlantic region. Periods of enhanced Agulhas Corridor salinity occur at Northern Hemisphere cool periods (glacial termination and Heinrich meltwater events) and are followed by rapid northern hemisphere warming. We show that the timing of maximal salinity events in relation to periods of North Atlantic freshwater perturbation is consistent with the concept suggested by climate models that Agulhas salinity oscillations could provide buoyancy compensation for the Atlantic and potentially even trigger increased convective activity in the North Atlantic, thereby restoring Atlantic overturning circulation after relatively weak states.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1064381.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1064381.pdf"><span>(<span class="hlt">Mis</span>)Conceptions about Geometric Shapes in Pre-Service Primary Teachers</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Žilková, Katarína; Guncaga, Ján; Kopácová, Janka</p> <p>2015-01-01</p> <p>During the last reform, Slovakia has reduced geometry in curriculum in primary mathematics education. Pre-school education schools devote more time to geometry in curriculum, but this is not mandatory for all the children. In the primary schools, teachers devote very little lessons time to this problem. These lessons are mainly focused on…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=information+AND+systems+AND+today&pg=2&id=EJ1098511','ERIC'); return false;" href="http://eric.ed.gov/?q=information+AND+systems+AND+today&pg=2&id=EJ1098511"><span>A Complementary Measure of <span class="hlt">MIS</span> Program Outcomes: Useful Insights from a Student Perspective</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Karsten, Rex; Roth, Roberta M.</p> <p>2015-01-01</p> <p>Assessing student learning is a critical element in today's higher education environment. Learning assurance programs seek to assess and improve the quality of student learning, and may employ both direct and indirect measures. In this paper, we describe a practical learning assurance assessment measure developed and used as a part of a broader…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=%22knowledge+translation%22&pg=3&id=EJ1014640','ERIC'); return false;" href="http://eric.ed.gov/?q=%22knowledge+translation%22&pg=3&id=EJ1014640"><span>(<span class="hlt">Mis</span>)Perceptions of Continuing Education: Insights from Knowledge Translation, Quality Improvement, and Patient Safety Leaders</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kitto, Simon C.; Bell, Mary; Goldman, Joanne; Peller, Jennifer; Silver, Ivan; Sargeant, Joan; Reeves, Scott</p> <p>2013-01-01</p> <p>Introduction: Minimal attention has been given to the intersection and potential collaboration among the domains of continuing education (CE), knowledge translation (KT), quality improvement (QI), and patient safety (PS), despite their overlapping objectives. A study was undertaken to examine leaders' perspectives of these 4 domains and their…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26525146','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26525146"><span>Use and <span class="hlt">mis</span>-use of supplementary material in science publications.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Pop, Mihai; Salzberg, Steven L</p> <p>2015-11-03</p> <p>Supplementary material is a ubiquitous feature of scientific articles, particularly in journals that limit the length of the articles. While the judicious use of supplementary material can improve the readability of scientific articles, its excessive use threatens the scientific review process and by extension the integrity of the scientific literature. In many cases supplementary material today is so extensive that it is reviewed superficially or not at all. Furthermore, citations buried within supplementary files rob other scientists of recognition of their contribution to the scientific record. These issues are exacerbated by the lack of guidance on the use of supplementary information from the journals to authors and reviewers. We propose that the removal of artificial length restrictions plus the use of interactive features made possible by modern electronic media can help to alleviate these problems. Many journals, in fact, have already removed article length limitations (as is the case for BMC Bioinformatics and other BioMed Central journals). We hope that the issues raised in our article will encourage publishers and scientists to work together towards a better use of supplementary information in scientific publishing.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27471136','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27471136"><span>Of Papers and Pens: Polysemes and Homophones in Lexical (<span class="hlt">mis</span>)Selection.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Li, Leon; Slevc, L Robert</p> <p>2016-07-29</p> <p>Every word signifies multiple senses. Many studies using comprehension-based measures suggest that polysemes' senses (e.g., paper as in printer paper or term paper) share lexical representations, whereas homophones' meanings (e.g., pen as in ballpoint pen or pig pen) correspond to distinct lexical representations. Less is known about the lexical representations of polysemes compared to homophones in language production. In this study, speakers named pictures after reading sentence fragments that primed polysemes and homophones either as direct competitors to pictures (i.e., semantic-competitors), or as indirect-competitors to pictures (e.g., polysemous senses of semantic competitors, or homophonous meanings of semantic competitors). Polysemes (e.g., paper) elicited equal numbers of intrusions to picture names (e.g., cardboard) compared to in control conditions whether primed as direct competitors (printer paper) or as indirect-competitors (term paper). This contrasted with the finding that homophones (e.g., pen) elicited more intrusions to picture names (e.g., crayon) compared to in control conditions when primed as direct competitors (ballpoint pen) than when primed as indirect-competitors (pig pen). These results suggest that polysemes, unlike homophones, are stored and retrieved as unified lexical representations.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=anonymous+OR+account+OR+123&id=EJ1071503','ERIC'); return false;" href="http://eric.ed.gov/?q=anonymous+OR+account+OR+123&id=EJ1071503"><span>Teacher (<span class="hlt">Mis</span>)Perceptions of Preschoolers' Academic Skills: Predictors and Associations with Longitudinal Outcomes</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Baker, Courtney N.; Tichovolsky, Marianne H.; Kupersmidt, Janis B.; Voegler-Lee, Mary Ellen; Arnold, David H.</p> <p>2015-01-01</p> <p>Preschool teachers have important impacts on children's academic outcomes, and teachers' misperceptions of children's academic skills could have negative consequences, particularly for low-income preschoolers. This study utilized data gathered from 123 preschool teachers and their 760 preschoolers from 70 low-income, racially diverse centers.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=international+AND+student+AND+behaviour&pg=6&id=EJ1052075','ERIC'); return false;" href="http://eric.ed.gov/?q=international+AND+student+AND+behaviour&pg=6&id=EJ1052075"><span>The Psychology of Containment: (<span class="hlt">Mis</span>) Representing Emotional and Behavioural Difficulties in Australian Schools</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Van Bergen, Penny; Graham, Linda J.; Sweller, Naomi; Dodd, Helen F.</p> <p>2015-01-01</p> <p>The number of students in special schools has increased at a rapid rate in some Australian states, due in part to increased enrolment under the categories of emotional disturbance (ED) and behaviour disorder (BD). Nonetheless, diagnostic distinctions between ED and BD are unclear. Moreover, despite international findings that students with…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=academic+AND+information+AND+system&pg=7&id=EJ830803','ERIC'); return false;" href="http://eric.ed.gov/?q=academic+AND+information+AND+system&pg=7&id=EJ830803"><span>Changes in Academic Dishonesty among <span class="hlt">MIS</span> Majors between 1999 and 2004</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Brown, Bob S.; Weible, Rick</p> <p>2006-01-01</p> <p>A questionnaire on academic dishonesty was administered to management information systems majors at an eastern state university in 1999 and 2004. The often-cited proposition that the level of student academic dishonesty among college and university students is increasing was unsupported. While the level of participation in one practice increased…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=food+AND+label&id=ED567323','ERIC'); return false;" href="http://eric.ed.gov/?q=food+AND+label&id=ED567323"><span>Language and Nutrition (<span class="hlt">Mis</span>)Information: Food Labels, FDA Policies and Meaning</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Taylor, Christy Marie</p> <p>2013-01-01</p> <p>In this dissertation, I address the ways in which food manufacturers can exploit the often vague and ambiguous nature of FDA policies concerning language and images used on food labels. Employing qualitative analysis methods (Strauss, 1987; Denzin and Lincoln, 2003; Mackey and Gass, 2005) that drew upon critical discourse analysis (Fairclough,…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4321741','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4321741"><span>Potential (<span class="hlt">mis</span>)match?: Marriage Markets amidst Socio-Demographic Change in India, 2005–2050</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kashyap, Ridhi; Esteve, Albert; García-Román, Joan</p> <p>2015-01-01</p> <p>We explore the impact of socio-demographic change on marriage patterns in India by examining the hypothetical consequences of applying three sets of marriage pairing propensities – contemporary patterns by age, by age and education, and changing propensities that allow for greater educational homogamy and reduced educational asymmetries – to future population projections. Future population prospects for India indicate three trends that will impact marriage patterns: i) female-deficit in sex ratios at birth; ii) declining birth cohort size; iii) female educational expansion. Existing literature posits declining marriage rates for men arising from skewed sex ratios at birth (SRB) in India’s population. In addition to skewed SRBs, India’s population will experience female educational expansion in the coming decades. Female educational expansion and its impact on marriage patterns must be jointly considered with demographic changes, given educational differentials and asymmetries in union formation that exist in India, as across much of the world. We systematize contemporary pairing propensities using data from the 2005–2006 Indian National Family Health Survey and the 2004 Socio-Economic Survey and apply these and the third set of changing propensities to IIASA/VID multi-state population projections by educational attainment using an iterative longitudinal projection procedure. If today’s age patterns of marriage are viewed against age-sex population composition until 2050, men experience declining marriage prevalence. However, when education is included, women, particularly those with higher education experience a more salient rise in non-marriage. Significant changes in pairing patterns towards greater levels of educational homogamy and gender symmetry can counteract a marked rise in non-marriage. PMID:25604846</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=transmission+AND+rates&pg=5&id=ED546675','ERIC'); return false;" href="http://eric.ed.gov/?q=transmission+AND+rates&pg=5&id=ED546675"><span>(<span class="hlt">Mis</span>)Aligned Ambitions? Parent Resources, Student Alignment, and Piecing Together the Hispanic College Puzzle</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ryan, Sarah Margaret</p> <p>2012-01-01</p> <p>The fact that Latina/o students are losing ground to their non-Latino White peers in four-year college enrollment and bachelor's degree attainment even as Latino college enrollment and graduation rates are at an all time high constitutes a perplexing puzzle. In order to realize the potential "demographic dividend" embedded in the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA635176','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA635176"><span>I Drank the Koolaid...Now What? <span class="hlt">MIS</span> After Two Years</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2009-05-01</p> <p>Support Center, Huntsville DALHART PBR, TX FUDS MMRP SI US Army Engineering and Support Center, Huntsville • Soil samples were collected from eight DU...locations at Dalhart PBRs 3 and 4. Seven of these DU locations were selected to represent areas with the highest likelihood for the presence of...MEC or MC contamination, and one DU location was selected for an ambient soil sample. US Army Engineering and Support Center, Huntsville DALHART PBR</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3179435','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3179435"><span>"Food company sponsors are kind, generous and cool": (<span class="hlt">Mis</span>)conceptions of junior sports players</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p></p> <p>2011-01-01</p> <p>Background Children's exposure to unhealthy food marketing influences their food knowledge, preferences and consumption. Sport sponsorship by food companies is widespread and industry investment in this marketing is increasing. This study aimed to assess children's awareness of sport sponsors and their brand-related attitudes and purchasing intentions in response to this marketing. Methods Sports clubs known to have food sponsors and representing the most popular sports for Australian children across a range of demographic areas were recruited. Interview-based questionnaires were conducted at clubs with children aged 10-14 years (n = 103) to examine their recall of local sports club and elite sport sponsors, and their attitudes towards sponsors and sponsorship activities. Results Most children (68%) could recall sponsors of their sports club, naming a median of two sponsors, including a median of one food company sponsor each. Almost half (47%) of children could recall any sponsors of their favourite elite sporting team. Children aged 10-11 years were more likely than older children to report that they thought about sponsors when buying something to eat or drink (P < 0.01); that they liked to return the favour to sponsors by buying their products (P < 0.01); and that sponsors were 'cool' (P = 0.02). Most children had received a voucher or certificate from a food or beverage company to reward sport performance (86% and 76%, respectively). Around one-third of children reported liking the company more after receiving these rewards. Conclusions Children's high recall of food and beverage company sport sponsors and their positive attitudes towards these sponsors and their promotions is concerning as this is likely to be linked to children's food preferences and consumption. Limiting children's exposure to this marketing is an important initiative to improve children's nutrition. PMID:21888675</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=robins&pg=6&id=EJ805939','ERIC'); return false;" href="http://eric.ed.gov/?q=robins&pg=6&id=EJ805939"><span>The (<span class="hlt">Mis</span>)Measurement of Job Performance in Child Welfare Using (Non)Experimental Design</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Lieberman, Alice A.; Levy, Michelle M.</p> <p>2006-01-01</p> <p>This commentary explicates two principal arguments against the conclusions drawn by Robin Perry in his article "Do Social Workers Make Better Child Welfare Workers Than Non-Social Workers?" The first concerns the methodology used, whereas the second centers on the measurement of the dependent variable, performance expectation. Considering the…</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_20");'>20</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li class="active"><span>22</span></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_22 --> <div id="page_23" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="441"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA159652','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA159652"><span>Investigation of High Speed ICs in InP Using <span class="hlt">MIS</span> Structures.</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1984-10-01</p> <p>3x3 digital multiplier for demonstration of the InP MISFET technolgy provides MSI levels of circuit integration as well as a self test mode of circuit...variables such as doping levels, oxide capacitance, mobility , transconductance, and even velocity saturation effects for short channel lengths. The end</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED440323.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED440323.pdf"><span>Correcting Media <span class="hlt">Mis</span>-Education: The Portrayal of Smokers and Smoking in Top Grossing Films.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bartlett, Alyssa; Brackin, Taryn; Chubb, Jamie; Covata, Sandy; Ferguson, Liz; Hinckley, Adele; Hodges, Jilda; Liberati, Cheryl; Tornetta, Jonette; Chambliss, Catherine</p> <p></p> <p>Given that young people are extremely concerned with how they appear socially, beguiling and glamorous portrayals of smokers in recent films may be contributing to the continual rise in college student smoking. The pervasive positive depiction of smokers as attractive and appealing easily preys on young people who lack confidence and self esteem.…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=20030016190&hterms=intelligence&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dintelligence','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=20030016190&hterms=intelligence&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D30%26Ntt%3Dintelligence"><span>Measuring the Performance and Intelligence of Systems: Proceedings of the 2002 Per<span class="hlt">MIS</span> Workshop</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Messina, E. R.; Meystel, A. M.</p> <p>2002-01-01</p> <p>Contents include the following: Performance Metrics; Performance of Multiple Agents; Performance of Mobility Systems; Performance of Planning Systems; General Discussion Panel 1; Uncertainty of Representation I; Performance of Robots in Hazardous Domains; Modeling Intelligence; Modeling of Mind; Measuring Intelligence; Grouping: A Core Procedure of Intelligence; Uncertainty in Representation II; Towards Universal Planning/Control Systems.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=facts+AND+eyes&pg=3&id=EJ1100532','ERIC'); return false;" href="http://eric.ed.gov/?q=facts+AND+eyes&pg=3&id=EJ1100532"><span>The (<span class="hlt">Mis</span>)use of the Finnish Teacher Education Model: "Policy-Based Evidence-Making"?</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Chung, Jennifer</p> <p>2016-01-01</p> <p>Background: International achievement studies such as the Programme for International Student Assessment (PISA) have an increasing influence on education policy worldwide. The use of such data can provide a basis for evidence-based policy-making to initiate educational reform. Finland, a high performer in PISA, is often cited as an example of both…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19940031984','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19940031984"><span>The (<span class="hlt">mis</span>)use of subjective process measures in software engineering</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Valett, Jon D.; Condon, Steven E.</p> <p>1993-01-01</p> <p>A variety of measures are used in software engineering research to develop an understanding of the software process and product. These measures fall into three broad categories: quantitative, characteristics, and subjective. Quantitative measures are those to which a numerical value can be assigned, for example effort or lines of code (LOC). Characteristics describe the software process or product; they might include programming language or the type of application. While such factors do not provide a quantitative measurement of a process or product, they do help characterize them. Subjective measures (as defined in this study) are those that are based on the opinion or opinions of individuals; they are somewhat unique and difficult to quantify. Capturing of subjective measure data typically involves development of some type of scale. For example, 'team experience' is one of the subjective measures that were collected and studied by the Software Engineering Laboratory (SEL). Certainly, team experience could have an impact on the software process or product; actually measuring a team's experience, however, is not a strictly mathematical exercise. Simply adding up each team member's years of experience appears inadequate. In fact, most researchers would agree that 'years' do not directly translate into 'experience.' Team experience must be defined subjectively and then a scale must be developed e.g., high experience versus low experience; or high, medium, low experience; or a different or more granular scale. Using this type of scale, a particular team's overall experience can be compared with that of other teams in the development environment. Defining, collecting, and scaling subjective measures is difficult. First, precise definitions of the measures must be established. Next, choices must be made about whose opinions will be solicited to constitute the data. Finally, care must be given to defining the right scale and level of granularity for measurement.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3277880','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3277880"><span>(<span class="hlt">Mis</span>)Perception of Sleep in Insomnia: A puzzle and a resolution</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Harvey, Allison G.; Tang, Nicole</p> <p>2011-01-01</p> <p>Insomnia is prevalent, causing severe distress and impairment. This review focuses on illuminating the puzzling finding that many insomnia patients misperceive their sleep. They overestimate their sleep onset latency (SOL) and underestimate their total sleep time (TST), relative to objective measures. This tendency is ubiquitous (although not universal). Resolving this puzzle has clinical, theoretical, and public health importance. There are implications for assessment, definition, and treatment. Moreover, solving the puzzle creates an opportunity for "real world" applications of theories from clinical, perceptual, and social psychology as well as neuroscience. Herein we evaluate thirteen possible resolutions to the puzzle. Specifically, we consider the possible contribution, to misperception, of: (1) features inherent to the context of sleep (e.g., darkness); (2) the definition of sleep onset which may lack sensitivity for insomnia patients; (3) insomnia being an exaggerated sleep complaint; (4) psychological distress causing magnification; (5) a deficit in time estimation ability; (6) sleep being misperceived as wake; (7) worry and selective attention toward sleep-related threats; (8) a memory bias influenced by current symptoms and emotions, a confirmation bias/belief bias or a recall bias linked to the intensity/recency of symptoms; (9) heightened physiological arousal; (10) elevated cortical arousal; (11) the presence of brief awakenings; (12) a fault in neuronal circuitry; and (13) there being two insomnia subtypes (one with and one without misperception). The best supported resolutions were misperception of sleep as wake, worry, and brief awakenings. A deficit in time estimation ability was not supported. We conclude by proposing several integrative solutions. PMID:21967449</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4096642','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4096642"><span>Primary Renal Hydatid Cyst: <span class="hlt">Mis</span>-Interpretation as a Renal Malignancy</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Choi, Hoon; Park, Jae Young; Kim, Jae-Heon; Moon, Du Geon; Lee, Jeong-Gu</p> <p>2014-01-01</p> <p>Primary renal echinococcosis, a rare disease involving the kidney, accounts for 2-3% of human echinococcosis. A 64-year-old female patient from Uzbekistan presented with complaints of left flank pain. A CT scan revealed a cystic mass in the upper to midpole of the left kidney. We regarded this lesion as a renal malignancy and hand-assisted laparoscopic radical nephrectomy was performed to remove the renal mass. The mass consisted of a large unilocular cyst and multiple smaller cysts without any grossly visible renal tissue. The final pathologic diagnosis was a renal hydatid cyst. For patients from endemic areas, hydatid cyst should be included in the differential diagnosis. Here, we present a case of renal hydatid cyst in a female patient who relocated from Uzbekistan to Korea. PMID:25031471</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20626685','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20626685"><span>(<span class="hlt">Mis</span>)understanding Safety Culture and Its Relationship to Safety Management.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Guldenmund, Frank W</p> <p>2010-10-01</p> <p>Although the concept of safety culture was coined in relation to major accidents like Chernobyl and Piper Alpha, it has been embraced by the safety community at large as a cause for unsafe practice. In this article, three approaches to safety culture are discussed in terms of their underlying concepts of culture and organizational culture. Culture is an intangible, fuzzy concept encompassing acquired assumptions that is shared among the members of a group and that provides meaning to their perceptions and actions and those of others. The basic assumptions that form the essence of a culture are shared, yet tacit, convictions, which manifest themselves subtly in the visible world. As applied by safety researchers, the culture concept is deprived of much of its depth and subtlety, and is morphed into a grab bag of behavioral and other visible characteristics, without reference to the meaning these characteristics might actually have, and often infused with normative overtones. By combining the three approaches, we can resurrect the notion of safety culture and strengthen its analytical potential in understanding the development and implementation of safety management systems.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA515942','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA515942"><span>Measuring the Performance and Intelligence of Systems: Proceedings of the 2001 Per<span class="hlt">MIS</span> Workshop</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2001-09-04</p> <p>35 1.1 Interval Mathematics for Analysis of Multiresolutional Systems V. Kreinovich, Univ. of Texas, R. Alo, Univ. of Houston-Downtown...the possible combinations. In non-deterministic real- time systems , the problem is compounded by the uncertainty in the execution times of various...multiresolutional, multiscale ) in their essence because of multiresolutional character of the meaning of words [Rieger, 01]. In integrating systems , the presence of a</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2009AGUFM.T53C1588M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2009AGUFM.T53C1588M"><span>Syntectonic fluid flux during rift faulting: Record from the <span class="hlt">MIS</span> core, Victoria Land Basin, Antarctica</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Millan, C.; Wilson, T. J.; Paulsen, T. S.</p> <p>2009-12-01</p> <p>The McMurdo Ice Shelf project successfully recovered 1285 m of Neogene sedimentary core from the Victoria Land Basin, a large rift basin within the West Antarctic Rift System (WARS) of Antarctica. The core contains 1475 natural fractures that were logged as faults, veins and clastic dikes, associated with the southern extension of the Neogene-active? Terror Rift fault zone. Veins constitute about 625 of this population. Most veins are filled with calcite, although zeolites and minor chlorite are common towards the bottom of the core. In the lower ~300 m of the core, veins contain opening-mode fiber fills and are wavy to tightly folded due to vertical shortening. Folded, opening-mode folded veins are filled by calcite fibers that grew normal to vein walls, indicating the host sediment was cohesive enough to fracture but was not fully lithified and accommodated vein buckling during compaction. Fold hinges are fractured and wedging of vein segments is marked by overlapping tips separated by zones with strong chlorite and clay fabrics, suggesting shearing during further vertical contraction of the host rock. Calcite veins are commonly strongly twinned. Cathodoluminescence microscopy shows minor changes in color and intensity and minimal concentric or sectoral zoning, suggesting relatively rapid crystallization of fluids of similar chemistry. However, stable isotope analyses reveal large variations in values, with carbon values ranging from -21.91 to -7.15 (VPBD) and oxygen values ranging from -5.35 to -11.97 (VPBD). Further detailed investigation of the fracture fills using cathodoluminescence and electron microscopy combined with isotopic analysis of carbon and oxygen will document the generations of the filling material in more detail and will constrain the sources and evolution of the fluids. There has clearly been significant structural control on fluid pathways during lithification, compaction and diagenesis of strata deforming within the Terror Rift zone.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=APPLIED+AND+RESEARCH&id=EJ1072624','ERIC'); return false;" href="http://eric.ed.gov/?q=APPLIED+AND+RESEARCH&id=EJ1072624"><span>Exploratory Factor Analysis as a Construct Validation Tool: (<span class="hlt">Mis</span>)applications in Applied Linguistics Research</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Karami, Hossein</p> <p>2015-01-01</p> <p>Factor analysis has been frequently exploited in applied research to provide evidence about the underlying factors in various measurement instruments. A close inspection of a large number of studies published in leading applied linguistic journals shows that there is a misconception among applied linguists as to the relative merits of exploratory…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4628792','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4628792"><span>Teacher (<span class="hlt">Mis</span>)Perceptions of Preschoolers’ Academic Skills: Predictors and Associations With Longitudinal Outcomes</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Baker, Courtney N.; Tichovolsky, Marianne H.; Kupersmidt, Janis B.; Voegler-Lee, Mary Ellen; Arnold, David H.</p> <p>2014-01-01</p> <p>Preschool teachers have important impacts on children’s academic outcomes, and teachers’ misperceptions of children’s academic skills could have negative consequences, particularly for low-income preschoolers. This study utilized data gathered from 123 preschool teachers and their 760 preschoolers from 70 low-income, racially diverse centers. Hierarchical linear modeling was utilized to account for the nested data structure. Even after controlling for children’s actual academic skill, older children, children with stronger social skills, and children with fewer inattentive symptoms were perceived to have stronger academic abilities. Contrary to hypotheses, preschoolers with more behavior problems were perceived by teachers to have significantly better pre-academic abilities than they actually had. Teachers’ perceptions were not associated with child gender or child race/ethnicity. Although considerable variability was due to teacher-level characteristics, child characteristics explained 42% of the variability in teachers’ perceptions about children’s language and pre-literacy ability and 41% of the variability in teachers’ perceptions about mathability. Notably, these perceptions appear to have important impacts over time. Controlling for child baseline academic skill and child characteristics, teacher perceptions early in the preschool year were significantly associated with child academic outcomes during the spring for both language and pre-literacy and math. Study implications with regard to the achievement gap are discussed. PMID:26538767</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=whales&pg=5&id=EJ581303','ERIC'); return false;" href="http://eric.ed.gov/?q=whales&pg=5&id=EJ581303"><span>Re-Birthing the Monstrous: James Whale's (<span class="hlt">Mis</span>)Reading of Mary Shelley's "Frankenstein."</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Picart, Caroline Joan S.</p> <p>1998-01-01</p> <p>Contributes to scholarship on film and feminism by showing how James Whale's film attempts to excise or severely delimit the disturbing critique of the Romantic politics of gender in Mary Shelley's novel "Frankenstein." Discusses parthenogenesis, showing how the novel critiques the Romantic rhetorical reconstructions of masculine…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JPhD...49x5204T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JPhD...49x5204T"><span>Role of vibrationally excited HBr in a HBr/He inductively coupled plasma used for etching of silicon</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tinck, Stefan; Bogaerts, Annemie</p> <p>2016-06-01</p> <p>In this work, the role of vibrationally excited HBr (HBr(<span class="hlt">vib</span>)) is computationally investigated for a HBr/He inductively coupled plasma applied for Si etching. It is found that at least 50% of all dissociations of HBr occur through HBr(<span class="hlt">vib</span>). This additional dissociation pathway through HBr(<span class="hlt">vib</span>) makes the plasma significantly more atomic. It also results in a slightly higher electron temperature (i.e. about 0.2 eV higher compared to simulation results where HBr(<span class="hlt">vib</span>) is not included), as well as a higher gas temperature (i.e. about 50 K higher than without including HBr(<span class="hlt">vib</span>)), due to the enhanced Franck-Condon heating through HBr(<span class="hlt">vib</span>) dissociation, at the conditions investigated. Most importantly, the calculated etch rate with HBr(<span class="hlt">vib</span>) included in the model is a factor 3 higher than in the case without HBr(<span class="hlt">vib</span>), due to the higher fluxes of etching species (i.e. H and Br), while the chemical composition of the wafer surface shows no significant difference. Our calculations clearly show the importance of including HBr(<span class="hlt">vib</span>) for accurate modeling of HBr-containing plasmas.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2013-04-19/pdf/2013-09177.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2013-04-19/pdf/2013-09177.pdf"><span>78 FR 23487 - Certain Outbound Property Transfers by Domestic Corporations; Certain Stock Distributions by...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2013-04-19</p> <p>... of Coordination Rule Exception in Sec. 1.367(a)-3(d)(2)(<span class="hlt">vi)(B</span>)(1)(i)'', line 24 from the top of the first full paragraph, the language ``or (d)(2)(<span class="hlt">vi)(b</span>)(1)(ii) are satisfied. The'' is corrected to...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ946615.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ946615.pdf"><span>Designing a Virtual Item Bank Based on the Techniques of Image Processing</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Liao, Wen-Wei; Ho, Rong-Guey</p> <p>2011-01-01</p> <p>One of the major weaknesses of the item exposure rates of figural items in Intelligence Quotient (IQ) tests lies in its inaccuracies. In this study, a new approach is proposed and a useful test tool known as the Virtual Item Bank (<span class="hlt">VIB</span>) is introduced. The <span class="hlt">VIB</span> combine Automatic Item Generation theory and image processing theory with the concepts of…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.osti.gov/scitech/servlets/purl/983100','DOE-PATENT-XML'); return false;" href="http://www.osti.gov/scitech/servlets/purl/983100"><span>Reactive codoping of GaAlInP compound semiconductors</span></a></p> <p><a target="_blank" href="http://www.osti.gov/doepatents">DOEpatents</a></p> <p>Hanna, Mark Cooper; Reedy, Robert</p> <p>2008-02-12</p> <p>A GaAlInP compound semiconductor and a method of producing a GaAlInP compound semiconductor are provided. The apparatus and method comprises a GaAs crystal substrate in a metal organic vapor deposition reactor. Al, Ga, In vapors are prepared by thermally decomposing organometallic compounds. P vapors are prepared by thermally decomposing phospine gas, group II vapors are prepared by thermally decomposing an organometallic group IIA or IIB compound. Group <span class="hlt">VIB</span> vapors are prepared by thermally decomposing a gaseous compound of group <span class="hlt">VIB</span>. The Al, Ga, In, P, group II, and group <span class="hlt">VIB</span> vapors grow a GaAlInP crystal doped with group IIA or IIB and group <span class="hlt">VIB</span> elements on the substrate wherein the group IIA or IIB and a group <span class="hlt">VIB</span> vapors produced a codoped GaAlInP compound semiconductor with a group IIA or IIB element serving as a p-type dopant having low group II atomic diffusion.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28113520','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28113520"><span>A Physics-Based Vibrotactile Feedback Library for Collision Events.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Park, Gunhyuk; Choi, Seungmoon</p> <p>2016-10-03</p> <p>We present Phys<span class="hlt">Vib</span>: a software solution on the mobile platform extending an open-source physics engine in a multi-rate rendering architecture for automatic vibrotactile feedback upon collision events. Phys<span class="hlt">Vib</span> runs concurrently with a physics engine at a low update rate and generates vibrotactile feedback commands at a high update rate based on the simulation results of the physics engine using an exponentially-decaying sinusoidal model. We demonstrate through a user study that this vibration model is more appropriate to our purpose in terms of perceptual quality than more complex models based on sound synthesis. We also evaluated the perceptual performance of Phys<span class="hlt">Vib</span> by comparing eight vibrotactile rendering methods. Experimental results suggested that Phys<span class="hlt">Vib</span> enables more realistic vibrotactile feedback than the other methods as to perceived similarity to the visual events. Phys<span class="hlt">Vib</span> is an effective solution for providing physically plausible vibrotactile responses while reducing application development time to great extent.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4782707','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4782707"><span>The (<span class="hlt">mis</span>)measurement of the Dark Triad Dirty Dozen: exploitation at the core of the scale</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kajonius, Petri J.; Persson, Björn N.; Rosenberg, Patricia</p> <p>2016-01-01</p> <p>Background. The dark side of human character has been conceptualized in the Dark Triad Model: Machiavellianism, psychopathy, and narcissism. These three dark traits are often measured using single long instruments for each one of the traits. Nevertheless, there is a necessity of short and valid personality measures in psychological research. As an independent research group, we replicated the factor structure, convergent validity and item response for one of the most recent and widely used short measures to operationalize these malevolent traits, namely, Jonason’s Dark Triad Dirty Dozen. We aimed to expand the understanding of what the Dirty Dozen really captures because the mixed results on construct validity in previous research. Method. We used the largest sample to date to respond to the Dirty Dozen (N = 3,698). We firstly investigated the factor structure using Confirmatory Factor Analysis and an exploratory distribution analysis of the items in the Dirty Dozen. Secondly, using a sub-sample (n = 500) and correlation analyses, we investigated the Dirty Dozen dark traits convergent validity to Machiavellianism measured by the Mach-IV, psychopathy measured by Eysenck’s Personality Questionnaire Revised, narcissism using the Narcissism Personality Inventory, and both neuroticism and extraversion from the Eysenck’s questionnaire. Finally, besides these Classic Test Theory analyses, we analyzed the responses for each Dirty Dozen item using Item Response Theory (IRT). Results. The results confirmed previous findings of a bi-factor model fit: one latent core dark trait and three dark traits. All three Dirty Dozen traits had a striking bi-modal distribution, which might indicate unconcealed social undesirability with the items. The three Dirty Dozen traits did converge too, although not strongly, with the contiguous single Dark Triad scales (r between .41 and .49). The probabilities of filling out steps on the Dirty Dozen narcissism-items were much higher than on the Dirty Dozen items for Machiavellianism and psychopathy. Overall, the Dirty Dozen instrument delivered the most predictive value with persons with average and high Dark Triad traits (theta > −0.5). Moreover, the Dirty Dozen scale was better conceptualized as a combined Machiavellianism-psychopathy factor, not narcissism, and is well captured with item 4: ‘I tend to exploit others towards my own end.’ Conclusion. The Dirty Dozen showed a consistent factor structure, a relatively convergent validity similar to that found in earlier studies. Narcissism measured using the Dirty Dozen, however, did not contribute with information to the core of the Dirty Dozen construct. More importantly, the results imply that the core of the Dirty Dozen scale, a manipulative and anti-social trait, can be measured by a Single Item Dirty Dark Dyad (SIDDD). PMID:26966673</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4206570','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4206570"><span>Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper <span class="hlt">mis</span>-regulation in Alzheimer’s disease</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Gonzalez, Paulina; da Costa, Viviana C.P.; Hyde, Kimberly; Wu, Qiong; Annunziata, Onofrio; Rizo, Josep; Akkaraju, Giridhar; Green, Kayla N.</p> <p>2014-01-01</p> <p>Oxidative stress resulting from metal-ion misregulation plays a role in the development of Alzheimer’s disease (AD). This process includes the production of tissue-damaging reactive oxygen species and amyloid aggregates. Herein we describe the synthesis, characterization and protective capacity of the small molecule, lipoic cyclen, which has been designed to target molecular features of AD. This construct utilizes the biologically compatible and naturally occurring lipoic acid as a foundation for engendering low cellular toxicity in multiple cell lines, radical scavenging capacity, tuning the metal affinity of the parent cyclen, and results in an unexpected affinity for amyloid without inducing aggregation. The hybrid construct thereby shows protection against cell death induced by amyloid aggregates and copper ions. These results provide evidence for the rational design methods used to produce this fused molecule as a potential strategy for the development of lead compounds for the treatment of neurodegenerative disorders. PMID:25144522</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=marketer&pg=6&id=ED496928','ERIC'); return false;" href="http://eric.ed.gov/?q=marketer&pg=6&id=ED496928"><span>The Internet Playground: Children's Access, Entertainment, and <span class="hlt">Mis</span>-Education. Second Printing. Popular Culture and Everyday Life Volume 10</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Seiter, Ellen</p> <p>2007-01-01</p> <p>Based on four years of experience teaching computers to 8-12 year olds, media scholar Ellen Seiter offers parents and educators practical advice on what children need to know about the Internet and when they need to know it. "The Internet Playground" argues that, contrary to the promises of technology boosters, teaching with computers is…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=American+AND+Dream&pg=3&id=EJ942380','ERIC'); return false;" href="http://eric.ed.gov/?q=American+AND+Dream&pg=3&id=EJ942380"><span>Racial Battle Fatigue and the "<span class="hlt">Mis</span>"Education of Black Men: Racial Microaggressions, Societal Problems, and Environmental Stress</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Smith, William A.; Hung, Man; Franklin, Jeremy D.</p> <p>2011-01-01</p> <p>Black men's lives are racialized contradictions, They are told that contemporary educational and professional institutions--particularly historically White institutions (HWls)--are places where, through hard work, they can achieve the so-called American dream. However, for far too many Black men, HWIs represent racial climates that are replete…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Historia&id=EJ1017102','ERIC'); return false;" href="http://eric.ed.gov/?q=Historia&id=EJ1017102"><span>Teachers' Memories of Schooling: The Sociocultural Injuries and the <span class="hlt">Mis</span>-Education of Mexican Teachers in the Barrio</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Saldana, Lilliana P.</p> <p>2013-01-01</p> <p>Relying on life history and memory as methodology, this essay unearths the memories of schooling of five Mexican American teachers at a dual-language school in San Antonio, locating their memories of trauma within the history of language oppression and cultural exclusion in U.S. public schools. In re(membering) their schooling experiences as…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28147266','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28147266"><span>Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint <span class="hlt">Mis</span>-regulation in Adults.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Van de Pette, Mathew; Abbas, Allifia; Feytout, Amelie; McNamara, Gráinne; Bruno, Ludovica; To, Wilson K; Dimond, Andrew; Sardini, Alessandro; Webster, Zoe; McGinty, James; Paul, Eleanor J; Ungless, Mark A; French, Paul M W; Withers, Dominic J; Uren, Anthony; Ferguson-Smith, Anne C; Merkenschlager, Matthias; John, Rosalind M; Fisher, Amanda G</p> <p>2017-01-31</p> <p>Imprinted genes are regulated according to parental origin and can influence embryonic growth and metabolism and confer disease susceptibility. Here, we designed sensitive allele-specific reporters to non-invasively monitor imprinted Cdkn1c expression in mice and showed that expression was modulated by environmental factors encountered in utero. Acute exposure to chromatin-modifying drugs resulted in de-repression of paternally inherited (silent) Cdkn1c alleles in embryos that was temporary and resolved after birth. In contrast, deprivation of maternal dietary protein in utero provoked permanent de-repression of imprinted Cdkn1c expression that was sustained into adulthood and occurred through a folate-dependent mechanism of DNA methylation loss. Given the function of imprinted genes in regulating behavior and metabolic processes in adults, these results establish imprinting deregulation as a credible mechanism linking early-life adversity to later-life outcomes. Furthermore, Cdkn1c-luciferase mice offer non-invasive tools to identify factors that disrupt epigenetic processes and strategies to limit their long-term impact.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED160384.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED160384.pdf"><span>Metrics, The Measure of Your Future: The Meter was Never Like This and Metric<span class="hlt">Mis</span>Quotes.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>North Carolina State Dept. of Public Instruction, Raleigh. Div. of Development.</p> <p></p> <p>Humorous imitations of famous poems and quotations, altered with metric language, are presented in this document published by the Winston-Salem/Forsyth County Schools Metric Education Project. In addition, a section entitled "A Metrikey" relates metric units to familiar items such as width of doorknobs, areas of typewriter keys, etc. (MP)</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18784327','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18784327"><span>The agreeableness asymmetry in first impressions: perceivers' impulse to (<span class="hlt">mis</span>)judge agreeableness and how it is moderated by power.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Ames, Daniel R; Bianchi, Emily C</p> <p>2008-12-01</p> <p>Prior research shows that perceivers can judge some traits better than others in first impressions of targets. However, questions remain about which traits perceivers naturally do infer. Here, the authors develop an account of the "agreeableness asymmetry": Although perceivers show little ability to accurately gauge target agreeableness in first impressions, they find that agreeableness is generally the most commonly inferred disposition among the Big Five dimensions of personality (agreeableness, extraversion, conscientiousness, openness, and emotional stability). Using open-ended impressions based on photographs, videos, and face-to-face encounters, three studies show agreeableness as the most prevalently judged of the Big Five, although it is also poorly judged in both absolute and relative terms. The authors use interpersonal power to reveal an underlying mechanism. Manipulating the power of perceivers relative to targets substantially shifts impression content, suggesting that habitual interaction and relational concerns may partially explain perceiver's chronic interest in assessing agreeableness despite their limited ability to do so.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26966673','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26966673"><span>The (<span class="hlt">mis</span>)measurement of the Dark Triad Dirty Dozen: exploitation at the core of the scale.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kajonius, Petri J; Persson, Björn N; Rosenberg, Patricia; Garcia, Danilo</p> <p>2016-01-01</p> <p>Background. The dark side of human character has been conceptualized in the Dark Triad Model: Machiavellianism, psychopathy, and narcissism. These three dark traits are often measured using single long instruments for each one of the traits. Nevertheless, there is a necessity of short and valid personality measures in psychological research. As an independent research group, we replicated the factor structure, convergent validity and item response for one of the most recent and widely used short measures to operationalize these malevolent traits, namely, Jonason's Dark Triad Dirty Dozen. We aimed to expand the understanding of what the Dirty Dozen really captures because the mixed results on construct validity in previous research. Method. We used the largest sample to date to respond to the Dirty Dozen (N = 3,698). We firstly investigated the factor structure using Confirmatory Factor Analysis and an exploratory distribution analysis of the items in the Dirty Dozen. Secondly, using a sub-sample (n = 500) and correlation analyses, we investigated the Dirty Dozen dark traits convergent validity to Machiavellianism measured by the Mach-IV, psychopathy measured by Eysenck's Personality Questionnaire Revised, narcissism using the Narcissism Personality Inventory, and both neuroticism and extraversion from the Eysenck's questionnaire. Finally, besides these Classic Test Theory analyses, we analyzed the responses for each Dirty Dozen item using Item Response Theory (IRT). Results. The results confirmed previous findings of a bi-factor model fit: one latent core dark trait and three dark traits. All three Dirty Dozen traits had a striking bi-modal distribution, which might indicate unconcealed social undesirability with the items. The three Dirty Dozen traits did converge too, although not strongly, with the contiguous single Dark Triad scales (r between .41 and .49). The probabilities of filling out steps on the Dirty Dozen narcissism-items were much higher than on the Dirty Dozen items for Machiavellianism and psychopathy. Overall, the Dirty Dozen instrument delivered the most predictive value with persons with average and high Dark Triad traits (theta > -0.5). Moreover, the Dirty Dozen scale was better conceptualized as a combined Machiavellianism-psychopathy factor, not narcissism, and is well captured with item 4: 'I tend to exploit others towards my own end.' Conclusion. The Dirty Dozen showed a consistent factor structure, a relatively convergent validity similar to that found in earlier studies. Narcissism measured using the Dirty Dozen, however, did not contribute with information to the core of the Dirty Dozen construct. More importantly, the results imply that the core of the Dirty Dozen scale, a manipulative and anti-social trait, can be measured by a Single Item Dirty Dark Dyad (SIDDD).</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=spending+AND+individual&pg=6&id=EJ1009538','ERIC'); return false;" href="http://eric.ed.gov/?q=spending+AND+individual&pg=6&id=EJ1009538"><span>Teaching Students What They Already Know? The (<span class="hlt">Mis</span>)Alignment between Mathematics Instructional Content and Student Knowledge in Kindergarten</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Engel, Mimi; Claessens, Amy; Finch, Maida A.</p> <p>2013-01-01</p> <p>Kindergarten mathematics skills are important for subsequent achievement, yet mathematics is underemphasized in kindergarten classrooms. Using nationally representative data, this study explored the relationship between students' school-entry math skills, classroom content coverage, and end-of-kindergarten math achievement. Although the vast…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA245212','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA245212"><span>Customized Blueprints to Enhance the Participation of HBCU/<span class="hlt">MIs</span> in DoD-Related R&D Programs</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1991-12-15</p> <p>to the DARPA super - Tractell (12/15/91) Page 11 ~~Tractell Final "ini 191 9t ucture thAt-wille iene i enxt, ditpro al submission. t ~ ~reque~sted bt...tradeoffs r.- ust be carefully weighted by the HBCU/MI institution on a case-by- case basis. I OVERVIEW OF THE PROPOSED TRACTELL PROJECT FOR 1992 The...2809 Director, CEES Business: Mr. William Ordone, 504 771-5550 Systems Analyst President: Dr. Dolores Spikes, 504 771-4680 STILLMAN COLLEGE P.O. Box</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1107960.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1107960.pdf"><span>(<span class="hlt">Mis</span>)Use of Email in Student-Faculty Interaction: Implications for University Instruction in Germany, Saudi Arabia, and Japan</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Danielewicz-Betz, Anna</p> <p>2013-01-01</p> <p>This paper examines student-faculty communication by email and the lack of clear guidelines that leads to misuse of email in student-faculty interaction, whereby status-incongruent pragmatic markers are employed, resulting in impoliteness and inappropriateness. The main objective is to bridge the gap in research on other than requestive speech…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=group+AND+dynamics+AND+affect+AND+student+AND+social+AND+interaction&id=EJ936378','ERIC'); return false;" href="http://eric.ed.gov/?q=group+AND+dynamics+AND+affect+AND+student+AND+social+AND+interaction&id=EJ936378"><span>Race, Gender, and Bodily (<span class="hlt">Mis</span>)Recognitions: Women of Color Faculty Experiences with White Students in the College Classroom</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Ford, Kristie A.</p> <p>2011-01-01</p> <p>Identities are not only shaped by self-perception, but are influenced by others' perceptions of self as well. More pointedly, one's physicality or bodily self can be perceived differently depending upon the viewer. To that end, Turner (2002) notes, "faculty women of color experience multiple marginality, characterized by lived contradiction…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/20824323','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/20824323"><span>How do children with ADHD (<span class="hlt">mis</span>)manage their real-life dyadic friendships? A multi-method investigation.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Normand, Sébastien; Schneider, Barry H; Lee, Matthew D; Maisonneuve, Marie-France; Kuehn, Sally M; Robaey, Philippe</p> <p>2011-02-01</p> <p>This multimethod study provides detailed information about the friendships of 87 children (76% boys) with ADHD and 46 comparison children aged 7-13 years. The methods included parent and teacher ratings, self-report measures and direct observation of friends' dyadic behaviors in three structured analogue tasks. Results indicated that, in contrast with comparison children, children with ADHD had friends with high levels of ADHD and oppositional symptoms; they perceived fewer positive features and more negative features, and were less satisfied in their friendships. Observational data indicated that children with ADHD performed both more legal and more illegal maneuvers than comparison children in a fast-paced competitive game. While negotiating with their friends, children with ADHD made more insensitive and self-centered proposals than comparison children. In dyads consisting of one child with ADHD and one typically developing child, children with ADHD were often more dominant than their friends.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2007AGUFM.U22B..07B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2007AGUFM.U22B..07B"><span>A Tropical Template for D-O Events During <span class="hlt">MIS</span> 3? Results From the Lake Malawi Drilling Project</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Brown, E. T.; Johnson, T. C.; Scholz, C. A.; King, J. W.; Cohen, A. S.</p> <p>2007-12-01</p> <p>As part of the Lake Malawi Drilling Project we have undertaken a 1 cm-scale resolution (ca. 20 yr) XRF scanning study of core from site 2A in the Northern Basin of the lake. We have focused on certain parameters, including Fe, Zr:Ti, and Si:Ti; these may be interpreted to represent changing input of terrigenous sediments (delivered to the lake by rivers), soils developed from weathered volcanic ash (delivered more effectively under drier windier conditions), and biogenic silica, respectively. We present here a record of East African climate since 55 ka that indicates rapid shifts between discrete climate modes that appear to be related to abrupt warming (Dansgaard- Oeschger) and cooling (Heinrich) events observed in Greenland. The events in Malawi appear to correspond to episodes of dry conditions and increased northerly winds. Such conditions may occur at times that southward excursion of the Intertropical Convergence Zone brings the tropical rain belt to the south of the study area. Although the timing of the Malawi events cannot be determined exactly, our independent age model, based on 25 radiocarbon dates and stratigraphic correlations to events dated in a nearby at 63 and 75 ka, implies that they occur prior to their Greenland counterparts, consistent with southward excursions of the ITCZ during Greenland stadials. The magnitude and form of each of the events recorded in Malawi sediments corresponds to the scale of the subsequent Greenland warming. This suggests that a tropical component of climate sets a template for abrupt high northern latitude climate fluctuations associated with the bipolar seesaw.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=gender+AND+stereotypes+AND+media&id=EJ973617','ERIC'); return false;" href="http://eric.ed.gov/?q=gender+AND+stereotypes+AND+media&id=EJ973617"><span>"This Is Not Reality...It's Only TV": African American Girls Respond to Media (<span class="hlt">Mis</span>)Representations</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Hall, Horace R.; Smith, Eleshia L.</p> <p>2012-01-01</p> <p>This research investigates the ways in which three African American high school girls interpret and challenge racialized and sexualized media representations of their race, class, and gender within music videos. The authors assert that these students' ability to counter stereotypes is a reflection of their cultural orientations, as well as their…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Analogue&pg=7&id=EJ915446','ERIC'); return false;" href="http://eric.ed.gov/?q=Analogue&pg=7&id=EJ915446"><span>How Do Children with ADHD (<span class="hlt">Mis</span>)Manage Their Real-Life Dyadic Friendships? A Multi-Method Investigation</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Normand, Sebastien; Schneider, Barry H.; Lee, Matthew D.; Maisonneuve, Marie-France; Kuehn, Sally M.; Robaey, Philippe</p> <p>2011-01-01</p> <p>This multimethod study provides detailed information about the friendships of 87 children (76% boys) with ADHD and 46 comparison children aged 7-13 years. The methods included parent and teacher ratings, self-report measures and direct observation of friends' dyadic behaviors in three structured analogue tasks. Results indicated that, in contrast…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=Lever&pg=5&id=EJ795361','ERIC'); return false;" href="http://eric.ed.gov/?q=Lever&pg=5&id=EJ795361"><span>When Do Motor Behaviors (<span class="hlt">Mis</span>)Match Affective Stimuli? An Evaluative Coding View of Approach and Avoidance Reactions</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Eder, Andreas B.; Rothermund, Klaus</p> <p>2008-01-01</p> <p>Affective-mapping effects between affective stimuli and lever movements are critically dependent upon the evaluative meaning of the response labels that are used in the task instructions. In Experiments 1 and 2, affective-mapping effects predicted by specific-muscle-activation and distance-regulation accounts were replicated when the standard…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10359299','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10359299"><span>Occurrence of methicillin-resistant and -susceptible Staphylococcus aureus within a single colony contributing to MRSA <span class="hlt">mis</span>-identification.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Falcão, M H; Texeira, L A; Ferreira-Carvalho, B T; Borges-Neto, A A; Figueiredo, A M</p> <p>1999-06-01</p> <p>Many methods have been described for the detection of methicillin-resistant Staphylococcus aureus (MRSA), but the homogeneous or heterogeneous expression of methicillin resistance affects the reliability of those methods. This study demonstrates that close association between methicillin-susceptible S. aureus (MSSA) and MRSA strains in the host colonisation site can present additional problems for the detection of MRSA in clinical laboratories, which may contribute to failure in the control of MRSA infection in hospital. Worse, this association may also account for the emergence of MRSA during antibiotic therapy.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4720448','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4720448"><span>Investigating the Influence of Climate Changes on Rodent Communities at a Regional-Scale (<span class="hlt">MIS</span> 1-3, Southwestern France)</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Royer, Aurélien; Montuire, Sophie; Legendre, Serge; Discamps, Emmanuel; Jeannet, Marcel; Lécuyer, Christophe</p> <p>2016-01-01</p> <p>Terrestrial ecosystems have continuously evolved throughout the Late Pleistocene and the Holocene, deeply affected by both progressive environmental and climatic modifications, as well as by abrupt and large climatic changes such as the Heinrich or Dansgaard-Oeschger events. Yet, the impacts of these different events on terrestrial mammalian communities are poorly known, as is the role played by potential refugia on geographical species distributions. This study examines community changes in rodents of southwestern France between 50 and 10 ky BP by integrating 94 dated faunal assemblages coming from 37 archaeological sites. This work reveals that faunal distributions were modified in response to abrupt and brief climatic events, such as Heinrich events, without actually modifying the rodent community on a regional scale. However, the succession of events which operated between the Late Pleistocene and the Holocene gradually led to establishing a new rodent community at the regional scale, with intermediate communities occurring between the Bølling and the Allerød. PMID:26789523</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015A%26A...582A..21B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015A%26A...582A..21B"><span>Tracing kinematic (<span class="hlt">mis</span>)alignments in CALIFA merging galaxies. Stellar and ionized gas kinematic orientations at every merger stage</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Barrera-Ballesteros, J. K.; García-Lorenzo, B.; Falcón-Barroso, J.; van de Ven, G.; Lyubenova, M.; Wild, V.; Méndez-Abreu, J.; Sánchez, S. F.; Marquez, I.; Masegosa, J.; Monreal-Ibero, A.; Ziegler, B.; del Olmo, A.; Verdes-Montenegro, L.; García-Benito, R.; Husemann, B.; Mast, D.; Kehrig, C.; Iglesias-Paramo, J.; Marino, R. A.; Aguerri, J. A. L.; Walcher, C. J.; Vílchez, J. M.; Bomans, D. J.; Cortijo-Ferrero, C.; González Delgado, R. M.; Bland-Hawthorn, J.; McIntosh, D. H.; Bekeraitė, S.</p> <p>2015-10-01</p> <p>We present spatially resolved stellar and/or ionized gas kinematic properties for a sample of 103 interacting galaxies, tracing all merger stages: close companions, pairs with morphological signatures of interaction, and coalesced merger remnants. In order to distinguish kinematic properties caused by a merger event from those driven by internal processes, we compare our galaxies with a control sample of 80 non-interacting galaxies. We measure for both the stellar and the ionized gas components the major (projected) kinematic position angles (PAkin, approaching and receding) directly from the velocity distributions with no assumptions on the internal motions. This method also allow us to derive the deviations of the kinematic PAs from a straight line (δPAkin). We find that around half of the interacting objects show morpho-kinematic PA misalignments that cannot be found in the control sample. In particular, we observe those misalignments in galaxies with morphological signatures of interaction. On the other hand, thelevel of alignment between the approaching and receding sides for both samples is similar, with most of the galaxies displaying small misalignments. Radial deviations of the kinematic PA orientation from a straight line in the stellar component measured by δPAkin are large for both samples. However, for a large fraction of interacting galaxies the ionized gas δPAkin is larger than the typical values derived from isolated galaxies (48%), indicating that this parameter is a good indicator to trace the impact of interaction and mergers in the internal motions of galaxies. By comparing the stellar and ionized gas kinematic PA, we find that 42% (28/66) of the interacting galaxies have misalignments larger than 16°, compared to 10% from the control sample. Our results show the impact of interactions in the motion of stellar and ionized gas as well as the wide the variety of their spatially resolved kinematic distributions. This study also provides a local Universe benchmark for kinematic studies in merging galaxies at high redshift. Appendices are available in electronic form at http://www.aanda.org</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18082111','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18082111"><span>[Sigmund Freud, Rudolf Meringer and Carl Mayer: slips of the tongue and <span class="hlt">mis</span>-readings. The history of a controversy].</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hinterhuber, Hartmann</p> <p>2007-01-01</p> <p>In both his The Psychopathology of Everyday Life and his Lectures Sigmund Freud derived the terms unconscious, preconscious and conscious, particularly from slips in speech, slips in reading and forgetfulness. In these slips, Freud recognised parallels to dreams. In the work mentioned, he analysed these in depth as part of mental motivation. In the papers referred to, Sigmund Freud paid tribute to Rudolf Meringer and Carl Mayer's study which was published in 1895. Meringer and Mayer showed as phenomena reversals and rearrangement of whole words, syllables or sounds, along with pre-tones or anticipations and echoes, word contaminations and word substitutions as responsible for slips of the tongue. The present work demonstrates how passionately these three scientists have contributed to the controversy of their standpoints. For modern psycholinguistics and the psychology of language, speech errors are always an expression of a momentary malfunction of the human speech production system: for the cognitive process of speech production slips of the tongue offer an insight into speech processing. Pre-tones and echoes, serialization errors, as Meringer and Mayer recognised, represent the vast majority of slips of the tongue. They do not reveal any hidden point. But with lexical-semantic slips of the tongue the question of mental motivation is admissible. This short paper is a sign of appreciation and gratitude: firstly, a modest birthday gift for Sigmund Freud, secondly homage to Carl Mayer, who influenced generations of neurologists in his 40 years of chairing the Psychiatric-Neurological Clinic in Innsbruck, so that Hans Ganner rightly spoke of a "Carl Mayer School". But lastly, this short study is also-and especially-a late recognition of Rudolf Meringer, the great Austrian linguist. The view an individual has concerning mental processes and the "topology of the psychic apparatus" is decisive as to the power of determination attached to the unconscious.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/EJ1105069.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/EJ1105069.pdf"><span><span class="hlt">Mis</span>/Representations of Asian/Americans in the Curricula: Perspectives from Second-Generation Japanese American Youth</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Endo, Rachel</p> <p>2012-01-01</p> <p>This case study explores how six second-generation Japanese American youth recalled learning about cultural diversity at their high schools, particularly information that was intended to represent their identities as ethnic and racial minorities. Semi-structured interviews were used to investigate how the participants made sense of curricular…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://files.eric.ed.gov/fulltext/ED448382.pdf','ERIC'); return false;" href="http://files.eric.ed.gov/fulltext/ED448382.pdf"><span><span class="hlt">Mis</span>-Diagnosis and Dual Diagnosis of Gifted Children: Gifted and LD, ADHD, OCD, Oppositional Defiant Disorder.</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Webb, James T.</p> <p></p> <p>Many gifted and talented children are often misdiagnosed by psychologists and other health professionals as having Attention Deficit Hyperactivity Disorder (ADHD), Oppositional Disorder (OD), Obsessive Compulsive Disorder (OCD), or another of the mood disorders. The misdiagnosis can stem from mistaken assumptions being made about the social and…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2012-12-06/pdf/2012-29441.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2012-12-06/pdf/2012-29441.pdf"><span>77 FR 72905 - Pipeline Safety: Random Drug Testing Rate; Contractor <span class="hlt">MIS</span> Reporting; and Obtaining DAMIS Sign-In...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2012-12-06</p> <p>... for Random Drug Testing Operators of gas, hazardous liquid, and carbon dioxide pipelines and operators of liquefied natural gas facilities must randomly select and test a percentage of covered employees..._Registration.pdf . Pursuant to 49 CFR Parts 199.119(a) and 199.229(a), operators with 50 or more...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=forgetfulness&id=EJ1039403','ERIC'); return false;" href="http://eric.ed.gov/?q=forgetfulness&id=EJ1039403"><span>(<span class="hlt">Mis</span>)Understanding Strategy as a "Spectacular Intervention": A Phenomenological Reflection on the Strategy Orientations Underpinning School Improvement in England</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Bates, Agnieszka</p> <p>2014-01-01</p> <p>The introduction of the "National Strategies" for primary education in 1998, positioned "strategy" as a powerful instrument for mobilising the school "workforce" in England in the cause of continuous improvement. Government approaches to strategy formulation and enactment appear to reflect an instrumentalist…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013PhyS...88a5801T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013PhyS...88a5801T"><span>The Richardson constant and barrier inhomogeneity at Au/Si3N4/n-Si (<span class="hlt">MIS</span>) Schottky diodes</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tataroğlu, A.; Pür, F. Z.</p> <p>2013-07-01</p> <p>Si3N4 films were deposited on n-type silicon substrate by the radio frequency magnetron sputtering technique. The current-voltage (I-V) characteristics of Au/Si3N4/n-Si (metal-insulator-semiconductor) Schottky diodes were investigated in the temperature range of 160-400 K. Experimental results show an abnormal increase in the zero-bias barrier height (BH) (ΦBo) and a decrease in the ideality factor (n) with increasing temperature. This behavior is attributed to barrier inhomogeneities by assuming a Gaussian distribution (GD) of BHs. The conventional Richardson plot (ln(Io/T2) versus 1000/T) exhibits a linearity above about 300 K. The values of activation energy (Ea) and Richardson constant (A*) were found to be 0.350 eV and 1.242 × 10-3 A cm-2 K-2 from the slope and the intercept at the ordinate of the linear region of this plot, respectively. Also, we attempted to draw a ΦBo versus q/2kT plot to determine evidence of the GD of BHs, and the values of \\bar \\Phi _{{\\rm{Bo}}} = 0.999\\,{\\rm{eV}} and σs = 0.137 eV for the mean BH and zero-bias standard deviation, respectively, were obtained from this plot; then, a modified ln(Io/T2) - q2σs2/2k2T2 versus q/kT plot gives \\bar \\Phi _{{\\rm{Bo}}} and A* as 0.992 eV and 108.228 A cm-2 K-2, respectively. This value of A* is very close to the theoretical value of 112 A cm-2 K-2 for n-type Si.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3181754','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3181754"><span>Psychosis related to neurological conditions: pro and cons of the dis- / <span class="hlt">mis</span>-connectivity models of schizophrenia</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Foucher, Jack R.; Luck, David</p> <p>2006-01-01</p> <p>Schizophrenia is still a condition with obscure causes and psychopathology. This paper aims to discuss the “disconnectivity” hypothesis in relation to some neurological conditions which are known to alter brain connectivity, as well as mimicking some aspects of the disorder. After a short historical introduction to the concept, we will examine the evidence for connectivity problems in schizophrenia, separating the anatomical level from the functional level. Then, we will discuss three different issues concerning connectivity: i) local reduction in connectivity without neuronal loss (within the gray matter); ii) reduction in or alteration of long-range connectivity (within the white matter); and iii) abnormal targets for connections. For each of these aspects, we will look at the conditions able to reproduce anomalies capable of increasing susceptibility to schizophrenia. We conclude that psychosis is more likely to occur: i) when long-range connectivity is concerned; ii) when lesions result in lengthening and scattering of conduction times; and iii) when there are high dopamine levels, shedding light on or adding weight to the idea of an interaction between dopamine and connectivity. PMID:16640110</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013CliPD...9..143S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013CliPD...9..143S"><span>Modeling dust emission response to <span class="hlt">MIS</span> 3 millennial climate variations from the perspective of East European loess deposits</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sima, A.; Kageyama, M.; Rousseau, D.-D.; Ramstein, G.; Balkanski, Y.; Antoine, P.; Hatté, C.</p> <p>2013-01-01</p> <p>European loess sequences of the last glacial period (~ 100-15 kyr BP) show periods of strong dust accumulation alternating with episodes of reduced sedimentation, favoring soil development. In the western part of the loess belt centered around 50° N, these variations appear to have been caused by the North Atlantic rapid climate changes: the Dansgaard-Oeschger (DO) and Heinrich (H) events. It has been recently suggested that the North-Atlantic climate signal can be detected further east, in loess deposits from Stayky (50° 05.65' N, 30° 53.92' E), Ukraine. Here we use climate and dust emission modeling to investigate this data interpretation. We focus on the areas north and northeast of the Carpathians, where loess deposits can be found, and the corresponding main dust sources must have been located as well. The simulations, performed with the LMDZ atmospheric general circulation model and the ORCHIDEE land-surface model, represent a Greenland stadial, a DO interstadial and an H event respectively. Placed in Marine Isotope Stage 3 (~ 60-25 kyr BP) conditions, they only differ by the surface conditions imposed in the North Atlantic between 30° and 63° N. The main source for the loess deposits in the studied area is identified as a dust deflation band, with two very active spots located west-northwest from our reference site. Emissions only occur between February and June. Differences from one deflation spot to another, and from one climate state to another, are explained by analyzing the relevant meteorological and surface variables. Over most of the source region, the annual emission fluxes in the "interstadial" experiment are 30 to 50% lower than the "stadial" values; they would only be about 20% lower if the inhibition of dust uplift by the vegetation were not taken into account. Assuming that lower emissions result in reduced dust deposition leads us to the conclusion that the loess-paleosol stratigraphic succession in the Stayky area reflects indeed North-Atlantic millennial variations. In the main deflation areas of Western Europe, the vegetation effect alone determined most of the ~ 50% stadial-interstadial flux differences. Even if its impact in Eastern Europe is less pronounced, this effect remains a key factor in modulating aeolian emissions at millennial timescale. Conditions favorable to initiating particularly strong dust storms within a few hundred kilometers upwind from our reference site, simulated in the month of April of the "H event" experiment, support the identification of H events as layers of particularly coarse sedimentation in some very detailed profiles.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3293829','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3293829"><span>Estimating the Burden of Malaria in Senegal: Bayesian Zero-Inflated Binomial Geostatistical Modeling of the <span class="hlt">MIS</span> 2008 Data</span></a></p> <p><a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Giardina, Federica; Gosoniu, Laura; Konate, Lassana; Diouf, Mame Birame; Perry, Robert; Gaye, Oumar; Faye, Ousmane; Vounatsou, Penelope</p> <p>2012-01-01</p> <p>The Research Center for Human Development in Dakar (CRDH) with the technical assistance of ICF Macro and the National Malaria Control Programme (NMCP) conducted in 2008/2009 the Senegal Malaria Indicator Survey (SMIS), the first nationally representative household survey collecting parasitological data and malaria-related indicators. In this paper, we present spatially explicit parasitaemia risk estimates and number of infected children below 5 years. Geostatistical Zero-Inflated Binomial models (ZIB) were developed to take into account the large number of zero-prevalence survey locations (70%) in the data. Bayesian variable selection methods were incorporated within a geostatistical framework in order to choose the best set of environmental and climatic covariates associated with the parasitaemia risk. Model validation confirmed that the ZIB model had a better predictive ability than the standard Binomial analogue. Markov chain Monte Carlo (MCMC) methods were used for inference. Several insecticide treated nets (ITN) coverage indicators were calculated to assess the effectiveness of interventions. After adjusting for climatic and socio-economic factors, the presence of at least one ITN per every two household members and living in urban areas reduced the odds of parasitaemia by 86% and 81% respectively. Posterior estimates of the ORs related to the wealth index show a decreasing trend with the quintiles. Infection odds appear to be increasing with age. The population-adjusted prevalence ranges from 0.12% in Thillé-Boubacar to 13.1% in Dabo. Tambacounda has the highest population-adjusted predicted prevalence (8.08%) whereas the region with the highest estimated number of infected children under the age of 5 years is Kolda (13940). The contemporary map and estimates of malaria burden identify the priority areas for future control interventions and provide baseline information for monitoring and evaluation. Zero-Inflated formulations are more appropriate in modeling sparse geostatistical survey data, expected to arise more frequently as malaria research is focused on elimination. PMID:22403684</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=problem+AND+Scholarship&pg=6&id=EJ964718','ERIC'); return false;" href="http://eric.ed.gov/?q=problem+AND+Scholarship&pg=6&id=EJ964718"><span>Perceiving the Problem of Poverty and Schooling: Deconstructing the Class Stereotypes that <span class="hlt">Mis</span>-Shape Education Practice and Policy</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Gorski, Paul C.</p> <p>2012-01-01</p> <p>A rich history of scholarship has demonstrated the ways in which popular stereotypes of disenfranchised communities, including people living in poverty, affect individual biases and preconceptions. Less attention has been paid to the ways in which such stereotypes help frame policy and practice responses regarding social problems, such as the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://eric.ed.gov/?q=verification+AND+testing&pg=3&id=EJ810211','ERIC'); return false;" href="http://eric.ed.gov/?q=verification+AND+testing&pg=3&id=EJ810211"><span>"So My Program Doesn't Run!" Definition, Origins, and Practical Expressions of Students' (<span class="hlt">Mis</span>)Conceptions of Correctness</span></a></p> <p><a target="_blank" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kolikant, Y. Ben-David; Mussai, M.</p> <p>2008-01-01</p> <p>We studied students' conceptions of correctness and their influence on students' correctness-related practices by examining how 159 students had analyzed the correctness of error-free and erroneous algorithms and by interviewing seven students regarding their work. We found that students conceptualized program correctness as the sum of the…</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26789523','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26789523"><span>Investigating the Influence of Climate Changes on Rodent Communities at a Regional-Scale (<span class="hlt">MIS</span> 1-3, Southwestern France).</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Royer, Aurélien; Montuire, Sophie; Legendre, Serge; Discamps, Emmanuel; Jeannet, Marcel; Lécuyer, Christophe</p> <p>2016-01-01</p> <p>Terrestrial ecosystems have continuously evolved throughout the Late Pleistocene and the Holocene, deeply affected by both progressive environmental and climatic modifications, as well as by abrupt and large climatic changes such as the Heinrich or Dansgaard-Oeschger events. Yet, the impacts of these different events on terrestrial mammalian communities are poorly known, as is the role played by potential refugia on geographical species distributions. This study examines community changes in rodents of southwestern France between 50 and 10 ky BP by integrating 94 dated faunal assemblages coming from 37 archaeological sites. This work reveals that faunal distributions were modified in response to abrupt and brief climatic events, such as Heinrich events, without actually modifying the rodent community on a regional scale. However, the succession of events which operated between the Late Pleistocene and the Holocene gradually led to establishing a new rodent community at the regional scale, with intermediate communities occurring between the Bølling and the Allerød.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://hdl.handle.net/2060/19920005431','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19920005431"><span><span class="hlt">Mis</span>Tec: A software application for supporting space exploration scenario options and technology development analysis and planning</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Horsham, Gary A. P.</p> <p>1991-01-01</p> <p>The structure and composition of a new, emerging software application, which models and analyzes space exploration scenario options for feasibility based on technology development projections is presented. The software application consists of four main components: a scenario generator for designing and inputting scenario options and constraints; a processor which performs algorithmic coupling and options analyses of mission activity requirements and technology capabilities; a results display which graphically and textually shows coupling and options analysis results; and a data/knowledge base which contains information on a variety of mission activities and (power and propulsion) technology system capabilities. The general long-range study process used by NASA to support recent studies is briefly introduced to provide the primary basis for comparison for discussing the potential advantages to be gained from developing and applying this king of application. A hypothetical example of a scenario option to facilitate the best conceptual understanding of what the application is, how it works, or the operating methodology, and when it might be applied is presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19920055866&hterms=development+planning&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Ddevelopment%2Bplanning','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19920055866&hterms=development+planning&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D40%26Ntt%3Ddevelopment%2Bplanning"><span><span class="hlt">Mis</span>Tec - A software application for supporting space exploration scenario options and technology development analysis and planning</span></a></p> <p><a target="_blank" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Horsham, Gary A. P.</p> <p>1992-01-01</p> <p>This structure and composition of a new, emerging software application, which models and analyzes space exploration scenario options for feasibility based on technology development projections is presented. The software application consists of four main components: a scenario generator for designing and inputting scenario options and constraints; a processor which performs algorithmic coupling and options analyses of mission activity requirements and technology capabilities; a results display which graphically and textually shows coupling and options analysis results; and a data/knowledge base which contains information on a variety of mission activities and (power and propulsion) technology system capabilities. The general long-range study process used by NASA to support recent studies is briefly introduced to provide the primary basis for comparison for discussing the potential advantages to be gained from developing and applying this kind of application. A hypothetical example of a scenario option to facilitate the best conceptual understanding of what the application is, how it works, or the operating methodology, and when it might be applied is presented.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA580095','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA580095"><span>A Framework for Human Microbiome Research</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>2012-06-14</p> <p>Bioethics , Humanities and Spiritual Care, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA. 38<span class="hlt">VIB</span>, Belgium, Department of Structural Biology, Pleinlaan 2...Pennsylvania, Center for Bioethics and Department of Medical Ethics, 3401 Market Street, Suite 320, Philadelphia, Pennsylvania 19104, USA</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-01-26/pdf/2011-1497.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-01-26/pdf/2011-1497.pdf"><span>76 FR 4540 - Approval and Disapproval and Promulgation of Air Quality Implementation Plans; Colorado...</span></a></p> <p><a target="_blank" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-01-26</p> <p>... changed the overall emission limit for petroleum and oil shale refineries from 0.3 lbs per barrel of oil... shale refining; (4) revisions to Section <span class="hlt">VI.B</span>.5 regarding SO 2 emission limits for new sources...</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017JThSc..26..125P','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017JThSc..26..125P"><span>Heat capacity and thermal expansion of water and helium</span></a></p> <p><a target="_blank" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Putintsev, N. M.; Putintsev, D. N.</p> <p>2017-04-01</p> <p>Original expressions for heat capacity CV and its components, vibrational and configurational components of thermal expansion coefficient were established. The values of CV, Cvib, Cconf, α<span class="hlt">vib</span> and αconf for water and helium 4He were calculated.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA174848','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA174848"><span>Cumulative Airport Noise Exposure Metrics: An Assessment of Evidence for Time-of-Day Weightings,</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1986-11-01</p> <p>effects. Recent reviews show that there is considerable disagreement about the effects of noise on task interference ( Loeb , 1980; Broadbent, 1983...The Response to Railway Noise in Residential Areas in Great Britain. J. Sound <span class="hlt">Vib</span>., vol. 85, no. 2, pp. 177-255. Francois, Jacques : 1977, La Prise en...F.J. and Buller, I.B.: 1977, Road Traffic Noise and Disturbance to Sleep. J. Sound <span class="hlt">Vib</span>., vol. 50, no.1, pp. 13-28. Loeb , M.: 1980, Noise and</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA214878','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA214878"><span>Cumulative Airport Noise Exposure Metrics: An Assessment of Evidence for Time-of-Day Weightings. Revision</span></a></p> <p><a target="_blank" href="https://publicaccess.dtic.mil/psm/api/service/search/search">DTIC Science & Technology</a></p> <p></p> <p>1989-11-01</p> <p>have not consistently shown effects. Recent reviews show that there is considerable disagreement about the effects of noise on task interference ( Loeb ...Response to Railway Noise in Residential Areas in Great Britain. J. Sound <span class="hlt">Vib</span>. , vol. 85, no. 2, pp. 177-255. Francois, Jacques : 1977, La Prise en...and Buller, I.B.: 1977, Road Traffic Noise and Disturbance to Sleep. J. Sound <span class="hlt">Vib</span>., vol. 50, no.1, pp. 13-28. Loeb , M.: 1980, Noise and Performance</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23281831','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23281831"><span>A novel vibratory stimulation-based occlusal splint for alleviation of TMD painful symptoms: a pilot study.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Hara, E S; Witzel, A L; de Luca, C E P; Ballester, R Y; Kuboki, T; Bolzan, M C</p> <p>2013-03-01</p> <p>This pilot study introduces a novel vibratory stimulation-based occlusal splint (<span class="hlt">Vib</span>OS) for management of pain related to temporomandibular disorders (TMD). The study sample consisted of 10 patients (mean age: 40·5 ± 13·7 years, male/female: 3/7) who were using stabilisation splints for more than 2 months prior to the study onset and still complained of pain. Patients utilised the active and inactive <span class="hlt">Vib</span>OS during 15 days in a crossover designed clinical trial. The analysed variables were self-reported VAS pain levels and number of painful sites to palpation (PSP). Statistical analysis was performed with repeated measures anova. At baseline, mean VAS pain levels for group I and II were 45·6 ± 21·0 mm and 37·4 ± 16·3 mm, respectively. Comparison between these baseline values showed no statistical difference (P > 0·05, unpaired t-test). In group I, the inactive <span class="hlt">Vib</span>OS caused a slight increase in VAS pain levels, whereas the active <span class="hlt">Vib</span>OS promoted a significant decrease in VAS pain levels and PSP (P < 0·01). In group II, which received the active <span class="hlt">Vib</span>OS first, a significant decrease in VAS levels (P < 0·05) and in PSP (P < 0·01) was observed. No significant decrease in VAS pain levels or PSP (P > 0·05) was observed with the use of the inactive <span class="hlt">Vib</span>OS. In conclusion, this study demonstrated a good tendency of this novel <span class="hlt">Vib</span>OS in the alleviation of painful symptoms related to TMD after a 15-day management period compared to control <span class="hlt">Vib</span>OS.</p> </li> <li> <p><a target="_blank" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23709641','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23709641"><span>Shaping motor cortex plasticity through proprioception.</span></a></p> <p><a target="_blank" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Avanzino, Laura; Pelosin, Elisa; Abbruzzese, Giovanni; Bassolino, Michela; Pozzo, Thierry; Bove, Marco</p> <p>2014-10-01</p> <p>Short-term upper limb disuse induces a hemispheric unbalance between the primary motor cortices (M1s). However, it is still unclear whether these changes are mainly attributable to the absence of voluntary movements or to the reduction of proprioceptive information. The goal of this work was to investigate the role of proprioception in modulating hemispheric balance during a short-term right arm immobilization. We evaluated the 2 M1s excitability and the interhemispheric inhibition (IHI) between M1s in 3 groups of healthy subjects. Two groups received during the immobilization a proprioceptive (P-<span class="hlt">VIB</span>, 80 Hz) and tactile (T-<span class="hlt">VIB</span>, 30 Hz) vibration to the right hand, respectively. Another group did not receive any conditioning sensory inputs (No-<span class="hlt">VIB</span>). We found that in the No-<span class="hlt">VIB</span> and in the T-<span class="hlt">VIB</span> groups immobilization induced a decrease of left M1 excitability and IHI from left to right hemisphere and an increase of right M1 excitability and IHI from right to left hemisphere. Differently, only a partial decrease in left M1 excitability, no change in right M1 excitability and in IHI was observed in the P-<span class="hlt">VIB</span> group. Our findings demonstrate that the maintenance of dynamic proprioceptive inputs in an immobilized arm through muscle vibration can prevent the hemispheric unbalance induced by short-term limb disuse.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <center> <div class="footer-extlink text-muted"><small>Some links on this page may take you to non-federal websites. 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