The US Food and Drug Administration's Risk Evaluation and Mitigation Strategy (REMS) Program - Current Status and Future Direction.

PubMed

Wu, Jasmanda; Juhaeri, Juhaeri

2016-12-01

The US Food and Drug Administration (FDA) Amendments Act of 2007 granted the FDA new authorities to enhance drug safety by requiring application holders to submit a proposed Risk Evaluation and Mitigation Strategy (REMS). A REMS is a required risk management plan that uses tools beyond the package insert. REMS elements may include a medication guide and patient package insert for patients and a communication plan focused on health care professionals. Elements to assure safe use (ETASUs) are put in place to mitigate a specific known serious risk when other less restrictive elements of a REMS are not sufficient to mitigate such risk. An implementation system is required for an REMS that includes the ETASUs. With approximately eight years of experience with REMS programs, many health care settings have created systems to manage REMS and also to integrate REMS into their practice settings. At the same time, there are issues associated with the development and implementation of REMS. In 2011, FDA created the REMS Integration Initiative to develop guidance on how to apply statutory criteria to determine when a REMS is required, to improve standardization and assessment of REMS, and to improve integration of REMS into the existing healthcare system. A key component of the REMS Integration Initiative is stakeholder outreach to better understand how existing REMS programs are working and to identify opportunities for improvement. This review attempts to share our company's experience with the REMS program, and to provide updates on FDA's efforts to improve REMS communication, to standardize REMS process, to reduce REMS program burdens and to build a common REMS platform. Copyright © 2016 Elsevier HS Journals, Inc. All rights reserved.

Automatized near-real-time short-term Probabilistic Volcanic Hazard Assessment of tephra dispersion before eruptions: BET_VHst for Vesuvius and Campi Flegrei during recent exercises

NASA Astrophysics Data System (ADS)

Selva, Jacopo; Costa, Antonio; Sandri, Laura; Rouwet, Dmtri; Tonini, Roberto; Macedonio, Giovanni; Marzocchi, Warner

2015-04-01

Probabilistic Volcanic Hazard Assessment (PVHA) represents the most complete scientific contribution for planning rational strategies aimed at mitigating the risk posed by volcanic activity at different time scales. The definition of the space-time window for PVHA is related to the kind of risk mitigation actions that are under consideration. Short temporal intervals (days to weeks) are important for short-term risk mitigation actions like the evacuation of a volcanic area. During volcanic unrest episodes or eruptions, it is of primary importance to produce short-term tephra fallout forecast, and frequently update it to account for the rapidly evolving situation. This information is obviously crucial for crisis management, since tephra may heavily affect building stability, public health, transportations and evacuation routes (airports, trains, road traffic) and lifelines (electric power supply). In this study, we propose a methodology named BET_VHst (Selva et al. 2014) for short-term PVHA of volcanic tephra dispersal based on automatic interpretation of measures from the monitoring system and physical models of tephra dispersal from all possible vent positions and eruptive sizes based on frequently updated meteorological forecasts. The large uncertainty at all the steps required for the analysis, both aleatory and epistemic, is treated by means of Bayesian inference and statistical mixing of long- and short-term analyses. The BET_VHst model is here presented through its implementation during two exercises organized for volcanoes in the Neapolitan area: MESIMEX for Mt. Vesuvius, and VUELCO for Campi Flegrei. References Selva J., Costa A., Sandri L., Macedonio G., Marzocchi W. (2014) Probabilistic short-term volcanic hazard in phases of unrest: a case study for tephra fallout, J. Geophys. Res., 119, doi: 10.1002/2014JB011252

UPDATE ON RADON MITIGATION RESEARCH IN SCHOOLS

EPA Science Inventory

The paper is an overview of research by EPA's Air and Energy Engineering Research Laboratory (AEERL) on radon mitigation in 47 schools since 1988. he structural and heating, ventilating, and air-conditioning (HVAC) system characteristics of the research schools are presented, alo...

An update on surgical and medical management strategies for intracerebral hemorrhage.

PubMed

Kreitzer, Natalie; Adeoye, Opeolu

2013-11-01

Intracerebral hemorrhage (ICH) accounts for ∼ 10 to 15% of all strokes and is one of the major causes of stroke-related death and disability. After the initial hemorrhage, further bleeding and edema contribute to secondary damage and worsened outcomes. As such, goals of previous and ongoing trials are to prevent continued bleeding, as well as mitigate the impact of cerebral edema. Although no trials have shown a definite functional outcome benefit with a given intervention, much progress has been made recently. This review focuses on recent developments that inform the acute management of ICH. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

A FAST ITERATIVE METHOD FOR SOLVING THE EIKONAL EQUATION ON TETRAHEDRAL DOMAINS

PubMed Central

Fu, Zhisong; Kirby, Robert M.; Whitaker, Ross T.

2014-01-01

Generating numerical solutions to the eikonal equation and its many variations has a broad range of applications in both the natural and computational sciences. Efficient solvers on cutting-edge, parallel architectures require new algorithms that may not be theoretically optimal, but that are designed to allow asynchronous solution updates and have limited memory access patterns. This paper presents a parallel algorithm for solving the eikonal equation on fully unstructured tetrahedral meshes. The method is appropriate for the type of fine-grained parallelism found on modern massively-SIMD architectures such as graphics processors and takes into account the particular constraints and capabilities of these computing platforms. This work builds on previous work for solving these equations on triangle meshes; in this paper we adapt and extend previous two-dimensional strategies to accommodate three-dimensional, unstructured, tetrahedralized domains. These new developments include a local update strategy with data compaction for tetrahedral meshes that provides solutions on both serial and parallel architectures, with a generalization to inhomogeneous, anisotropic speed functions. We also propose two new update schemes, specialized to mitigate the natural data increase observed when moving to three dimensions, and the data structures necessary for efficiently mapping data to parallel SIMD processors in a way that maintains computational density. Finally, we present descriptions of the implementations for a single CPU, as well as multicore CPUs with shared memory and SIMD architectures, with comparative results against state-of-the-art eikonal solvers. PMID:25221418

Destructive Interactions Between Mitigation Strategies and the Causes of Unexpected Failures in Natural Hazard Mitigation Systems

NASA Astrophysics Data System (ADS)

Day, S. J.; Fearnley, C. J.

2013-12-01

Large investments in the mitigation of natural hazards, using a variety of technology-based mitigation strategies, have proven to be surprisingly ineffective in some recent natural disasters. These failures reveal a need for a systematic classification of mitigation strategies; an understanding of the scientific uncertainties that affect the effectiveness of such strategies; and an understanding of how the different types of strategy within an overall mitigation system interact destructively to reduce the effectiveness of the overall mitigation system. We classify mitigation strategies into permanent, responsive and anticipatory. Permanent mitigation strategies such as flood and tsunami defenses or land use restrictions, are both costly and 'brittle': when they malfunction they can increase mortality. Such strategies critically depend on the accuracy of the estimates of expected hazard intensity in the hazard assessments that underpin their design. Responsive mitigation strategies such as tsunami and lahar warning systems rely on capacities to detect and quantify the hazard source events and to transmit warnings fast enough to enable at risk populations to decide and act effectively. Self-warning and voluntary evacuation is also usually a responsive mitigation strategy. Uncertainty in the nature and magnitude of the detected hazard source event is often the key scientific obstacle to responsive mitigation; public understanding of both the hazard and the warnings, to enable decision making, can also be a critical obstacle. Anticipatory mitigation strategies use interpretation of precursors to hazard source events and are used widely in mitigation of volcanic hazards. Their critical limitations are due to uncertainties in time, space and magnitude relationships between precursors and hazard events. Examples of destructive interaction between different mitigation strategies are provided by the Tohoku 2011 earthquake and tsunami; recent earthquakes that have impacted population centers with poor enforcement of building codes, unrealistic expectations of warning systems or failures to understand local seismic damage mechanisms; and the interaction of land use restriction strategies and responsive warning strategies around lahar-prone volcanoes. A more complete understanding of the interactions between these different types of mitigation strategy, especially the consequences for the expectations and behaviors of the populations at risk, requires models of decision-making under high levels of both uncertainty and danger. The Observation-Orientation-Decision-Action (OODA) loop model (Boyd, 1987) may be a particularly useful model. It emphasizes the importance of 'orientation' (the interpretation of observations and assessment of their significance for the observer and decision-maker), the feedback between decisions and subsequent observations and orientations, and the importance of developing mitigation strategies that are flexible and so able to respond to the occurrence of the unexpected. REFERENCE: Boyd, J.R. A Discourse on Winning and Losing [http://dnipogo.org/john-r-boyd/

When the Sun's Away, N2O5 Comes Out to Play: An Updated Analysis of Ambient N2O5 Heterogeneous Chemistry

NASA Astrophysics Data System (ADS)

McDuffie, E. E.; Brown, S. S.

2017-12-01

The heterogeneous chemistry of N2O5 impacts the budget of tropospheric oxidants, which directly controls air quality at Earth's surface. The reaction between gas-phase N2O5 and aerosol particles occurs largely at night, and is therefore more important during the less-intensively-studied winter season. Though N2O5-aerosol interactions are vital for the accurate understanding and simulation of tropospheric chemistry and air quality, many uncertainties persist in our understanding of how various environmental factors influence the reaction rate and probability. Quantitative and accurate evaluation of these factors directly improves the predictive capabilities of atmospheric models, used to inform mitigation strategies for wintertime air pollution. In an update to last year's presentation, The Wintertime Fate of N2O5: Observations and Box Model Analysis for the 2015 WINTER Aircraft Campaign, this presentation will focus on recent field results regarding new information about N2O5 heterogeneous chemistry and future research directions.

Regional action plan handling of social welfare problem in nganjuk regency

NASA Astrophysics Data System (ADS)

Zain, IM; Utami, WS; Setyawan, KG

2018-01-01

Local action plans are expected to ensure a social protection for vulnerable and disadvantaged groups or PMKS. The method used in this research is by primary survey and secondary survey. The condition of the people who still belong to PMKS requires the state to come to the community to solve the problems faced. Stakeholders should be involved to handle PMKS. The activities presented should also receive periodic monitoring and evaluation so that there is progress reporting at any time. Implementable poverty reduction strategies and policies are social protection strategies, opportunity expansion strategies, resource capacity building strategies, community empowerment strategies and partnership strategies. The flow of PMKS is the validation and updating of data, the fulfillment of the basic needs of the PMKS family, the development of PMKS human resources, the improvement of the quality of life for poor families, the institutions of poverty alleviation stakeholders and the unemployed at the base level. The Regional Action Plan (RAP) is prepared as a reference in the context of carrying out PMKS mitigation which is expected to serve as a guide for managers and program implementers with relevant agencies that are conducted jointly and continuously for the period of time specified.

HYPOXIA IN THE NORTHERN GULF OF MEXICO: DOES THE SCIENCE SUPPORT THE PLAN TO REDUCE, MITIGATE, AND CONTROL HYPOXIA?

EPA Science Inventory

We update and reevaluate the scientific information on the distribution, history and causes of continental shelf hypoxia that supports the 2001 "Action Plan for Reducing, Mitigating, and Controlling Hypoxiain the Northern Gulf of Mexico," incorporating data, publications, and res...

Wicked Problems in Natural Hazard Assessment and Mitigation

NASA Astrophysics Data System (ADS)

Stein, S.; Steckler, M. S.; Rundle, J. B.; Dixon, T. H.

2017-12-01

Social scientists have defined "wicked" problems that are "messy, ill-defined, more complex than we fully grasp, and open to multiple interpretations based on one's point of view... No solution to a wicked problem is permanent or wholly satisfying, which leaves every solution open to easy polemical attack." These contrast with "tame" problems in which necessary information is available and solutions - even if difficult and expensive - are straightforward to identify and execute. Updating the U.S.'s aging infrastructure is a tame problem, because what is wrong and how to fix it are clear. In contrast, addressing climate change is a wicked problem because its effects are uncertain and the best strategies to address them are unclear. An analogous approach can be taken to natural hazard problems. In tame problems, we have a good model of the process, good information about past events, and data implying that the model should predict future events. In such cases, we can make a reasonable assessment of the hazard that can be used to develop mitigation strategies. Earthquake hazard mitigation for San Francisco is a relatively tame problem. We understand how the earthquakes result from known plate motions, have information about past earthquakes, and have geodetic data implying that future similar earthquakes will occur. As a result, it is straightforward to develop and implement mitigation strategies. However, in many cases, hazard assessment and mitigation is a wicked problem. How should we prepare for a great earthquake on plate boundaries where tectonics favor such events but we have no evidence that they have occurred and hence how large they may be or how often to expect them? How should we assess the hazard within plates, for example in the New Madrid seismic zone, where large earthquakes have occurred but we do not understand their causes and geodetic data show no strain accumulating? How can we assess the hazard and make sensible policy when the recurrence of earthquakes, floods, or hurricanes seems to be changing with time or is expected to do so due to human activity? A starting approach might be to assess what we know, what we don't know, what we think, and what can be done that might improve this situation. We should draw on what is known in other areas of risk assessment including social science, meteorology, engineering, and economics.

Environmental development plan for transportation programs: FY80 update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saricks, C.L.; Singh, M.K.; Bernard, M.J. III

1980-09-01

This is the second annual update of the environmental development plan (EDP) for transportation programs. It has been prepared as a cooperative effort of the Assistant Secretaries for Conservation and Solar Energy (ASCS) Office of Transportation Programs (CS/TP) and the Environment (ASEV) Office of Environmental Assessments. EDPs identify the ecosystem, resource, physical environment, health, safety, socioeconomic, and environmental control concerns associated with DOE programs. The programs include the research, development, demonstration, and assessment (RDD and A) of 14 transportation technologies and several strategy implementation projects. This EDP update presents a research and assessment plan for resolving any potentially adverse environmentalmore » concerns arising from these programs. The EDP process provides a framework for: incorporating environmental concerns into CS/TP planning and decision processes early to ensure they are assigned the same importance as technological, fiscal, and institutional concerns in decision making; resolving environmental concerns concurrently with energy technology and strategy development; and providing a research schedule that mitigates adverse environmental effects through sound technological design or policy analysis. This EDP also describes the status of each environmental concern and the plan for its resolution. Much of ongoing DOE reseirch and technology development is aimed at resolving concerns identified in this EDP. Each EDP is intended to be so comprehensive that no concerns escape notice. Care is taken to include any CS/TP action that may eventually require an Environmental Impact Statement. Because technology demonstration and commercialization tend to raise more environmental concerns than other portions of the transportation program, most of this EDP addresses these concerns.« less

Financial Impact of Cancer Drug Wastage and Potential Cost Savings From Mitigation Strategies.

PubMed

Leung, Caitlyn Y W; Cheung, Matthew C; Charbonneau, Lauren F; Prica, Anca; Ng, Pamela; Chan, Kelvin K W

2017-07-01

Cancer drug wastage occurs when a parenteral drug within a fixed vial is not administered fully to a patient. This study investigated the extent of drug wastage, the financial impact on the hospital budget, and the cost savings associated with current mitigation strategies. We conducted a cross-sectional study in three University of Toronto-affiliated hospitals of various sizes. We recorded the actual amount of drug wasted over a 2-week period while using current mitigation strategies. Single-dose vial cancer drugs with the highest wastage potentials were identified (14 drugs). To calculate the hypothetical drug wastage with no mitigation strategies, we determined how many vials of drugs would be needed to fill a single prescription. The total drug costs over the 2 weeks ranged from $50,257 to $716,983 in the three institutions. With existing mitigation strategies, the actual drug wastage over the 2 weeks ranged from $928 to $5,472, which was approximately 1% to 2% of the total drug costs. In the hypothetical model with no mitigation strategies implemented, the projected drug cost wastage would have been $11,232 to $149,131, which accounted for 16% to 18% of the total drug costs. As a result, the potential annual savings while using current mitigation strategies range from 15% to 17%. The financial impact of drug wastage is substantial. Mitigation strategies lead to substantial cost savings, with the opportunity to reinvest those savings. More research is needed to determine the appropriate methods to minimize risk to patients while using the cost-saving mitigation strategies.

Public perceptions about climate change mitigation in British Columbia's forest sector

PubMed Central

Hagerman, Shannon; Kozak, Robert; Hoberg, George

2018-01-01

The role of forest management in mitigating climate change is a central concern for the Canadian province of British Columbia. The successful implementation of forest management activities to achieve climate change mitigation in British Columbia will be strongly influenced by public support or opposition. While we now have increasingly clear ideas of the management opportunities associated with forest mitigation and some insight into public support for climate change mitigation in the context of sustainable forest management, very little is known with respect to the levels and basis of public support for potential forest management strategies to mitigate climate change. This paper, by describing the results of a web-based survey, documents levels of public support for the implementation of eight forest carbon mitigation strategies in British Columbia’s forest sector, and examines and quantifies the influence of the factors that shape this support. Overall, respondents ascribed a high level of importance to forest carbon mitigation and supported all of the eight proposed strategies, indicating that the British Columbia public is inclined to consider alternative practices in managing forests and wood products to mitigate climate change. That said, we found differences in levels of support for the mitigation strategies. In general, we found greater levels of support for a rehabilitation strategy (e.g. reforestation of unproductive forest land), and to a lesser extent for conservation strategies (e.g. old growth conservation, reduced harvest) over enhanced forest management strategies (e.g. improved harvesting and silvicultural techniques). We also highlighted multiple variables within the British Columbia population that appear to play a role in predicting levels of support for conservation and/or enhanced forest management strategies, including environmental values, risk perception, trust in groups of actors, prioritized objectives of forest management and socio-demographic factors. PMID:29684041

Public perceptions about climate change mitigation in British Columbia's forest sector.

PubMed

Peterson St-Laurent, Guillaume; Hagerman, Shannon; Kozak, Robert; Hoberg, George

2018-01-01

The role of forest management in mitigating climate change is a central concern for the Canadian province of British Columbia. The successful implementation of forest management activities to achieve climate change mitigation in British Columbia will be strongly influenced by public support or opposition. While we now have increasingly clear ideas of the management opportunities associated with forest mitigation and some insight into public support for climate change mitigation in the context of sustainable forest management, very little is known with respect to the levels and basis of public support for potential forest management strategies to mitigate climate change. This paper, by describing the results of a web-based survey, documents levels of public support for the implementation of eight forest carbon mitigation strategies in British Columbia's forest sector, and examines and quantifies the influence of the factors that shape this support. Overall, respondents ascribed a high level of importance to forest carbon mitigation and supported all of the eight proposed strategies, indicating that the British Columbia public is inclined to consider alternative practices in managing forests and wood products to mitigate climate change. That said, we found differences in levels of support for the mitigation strategies. In general, we found greater levels of support for a rehabilitation strategy (e.g. reforestation of unproductive forest land), and to a lesser extent for conservation strategies (e.g. old growth conservation, reduced harvest) over enhanced forest management strategies (e.g. improved harvesting and silvicultural techniques). We also highlighted multiple variables within the British Columbia population that appear to play a role in predicting levels of support for conservation and/or enhanced forest management strategies, including environmental values, risk perception, trust in groups of actors, prioritized objectives of forest management and socio-demographic factors.

Current available strategies to mitigate greenhouse gas emissions in livestock systems: an animal welfare perspective.

PubMed

Llonch, P; Haskell, M J; Dewhurst, R J; Turner, S P

2017-02-01

Livestock production is a major contributor to greenhouse gas (GHG) emissions, so will play a significant role in the mitigation effort. Recent literature highlights different strategies to mitigate GHG emissions in the livestock sector. Animal welfare is a criterion of sustainability and any strategy designed to reduce the carbon footprint of livestock production should consider animal welfare amongst other sustainability metrics. We discuss and tabulate the likely relationships and trade-offs between the GHG mitigation potential of mitigation strategies and their welfare consequences, focusing on ruminant species and on cattle in particular. The major livestock GHG mitigation strategies were classified according to their mitigation approach as reducing total emissions (inhibiting methane production in the rumen), or reducing emissions intensity (Ei; reducing CH4 per output unit without directly targeting methanogenesis). Strategies classified as antimethanogenic included chemical inhibitors, electron acceptors (i.e. nitrates), ionophores (i.e. Monensin) and dietary lipids. Increasing diet digestibility, intensive housing, improving health and welfare, increasing reproductive efficiency and breeding for higher productivity were categorized as strategies that reduce Ei. Strategies that increase productivity are very promising ways to reduce the livestock carbon footprint, though in intensive systems this is likely to be achieved at the cost of welfare. Other strategies can effectively reduce GHG emissions whilst simultaneously improving animal welfare (e.g. feed supplementation or improving health). These win-win strategies should be strongly supported as they address both environmental and ethical sustainability. In order to identify the most cost-effective measures for improving environmental sustainability of livestock production, the consequences of current and future strategies for animal welfare must be scrutinized and contrasted against their effectiveness in mitigating climate change.

Acrylamide mitigation strategies: critical appraisal of the FoodDrinkEurope toolbox.

PubMed

Palermo, M; Gökmen, V; De Meulenaer, B; Ciesarová, Z; Zhang, Y; Pedreschi, F; Fogliano, V

2016-06-15

FoodDrinkEurope Federation recently released the latest version of the Acrylamide Toolbox to support manufacturers in acrylamide reduction activities giving indication about the possible mitigation strategies. The Toolbox is intended for small and medium size enterprises with limited R&D resources, however no comments about the pro and cons of the different measures were provided to advise the potential users. Experts of the field are aware that not all the strategies proposed have equal value in terms of efficacy and cost/benefit ratio. This consideration prompted us to provide a qualitative science-based ranking of the mitigation strategies proposed in the acrylamide Toolbox, focusing on bakery and fried potato products. Five authors from different geographical areas having a publication record on acrylamide mitigation strategies worked independently ranking the efficacy of the acrylamide mitigation strategies taking into account three key parameters: (i) reduction rate; (ii) side effects; and (iii) applicability and economic impact. On the basis of their own experience and considering selected literature of the last ten years, the authors scored for each key parameter the acrylamide mitigation strategies proposed in the Toolbox. As expected, all strategies selected in the Toolbox turned out to be useful, however, not at the same level. The use of enzyme asparaginase and the selection of low sugar varieties were considered the best mitigation strategies in bakery and in potato products, respectively. According to authors' opinion most of the other mitigation strategies, although effective, either have relevant side effects on the sensory profile of the products, or they are not easy to implement in industrial production. The final outcome was a science based commented ranking which can enrich the acrylamide Toolbox supporting individual manufacturer in taking the best actions to reduce the acrylamide content in their specific production context.

A Novel Unsupervised Adaptive Learning Method for Long-Term Electromyography (EMG) Pattern Recognition

PubMed Central

Huang, Qi; Yang, Dapeng; Jiang, Li; Zhang, Huajie; Liu, Hong; Kotani, Kiyoshi

2017-01-01

Performance degradation will be caused by a variety of interfering factors for pattern recognition-based myoelectric control methods in the long term. This paper proposes an adaptive learning method with low computational cost to mitigate the effect in unsupervised adaptive learning scenarios. We presents a particle adaptive classifier (PAC), by constructing a particle adaptive learning strategy and universal incremental least square support vector classifier (LS-SVC). We compared PAC performance with incremental support vector classifier (ISVC) and non-adapting SVC (NSVC) in a long-term pattern recognition task in both unsupervised and supervised adaptive learning scenarios. Retraining time cost and recognition accuracy were compared by validating the classification performance on both simulated and realistic long-term EMG data. The classification results of realistic long-term EMG data showed that the PAC significantly decreased the performance degradation in unsupervised adaptive learning scenarios compared with NSVC (9.03% ± 2.23%, p < 0.05) and ISVC (13.38% ± 2.62%, p = 0.001), and reduced the retraining time cost compared with ISVC (2 ms per updating cycle vs. 50 ms per updating cycle). PMID:28608824

A Novel Unsupervised Adaptive Learning Method for Long-Term Electromyography (EMG) Pattern Recognition.

PubMed

Huang, Qi; Yang, Dapeng; Jiang, Li; Zhang, Huajie; Liu, Hong; Kotani, Kiyoshi

2017-06-13

Performance degradation will be caused by a variety of interfering factors for pattern recognition-based myoelectric control methods in the long term. This paper proposes an adaptive learning method with low computational cost to mitigate the effect in unsupervised adaptive learning scenarios. We presents a particle adaptive classifier (PAC), by constructing a particle adaptive learning strategy and universal incremental least square support vector classifier (LS-SVC). We compared PAC performance with incremental support vector classifier (ISVC) and non-adapting SVC (NSVC) in a long-term pattern recognition task in both unsupervised and supervised adaptive learning scenarios. Retraining time cost and recognition accuracy were compared by validating the classification performance on both simulated and realistic long-term EMG data. The classification results of realistic long-term EMG data showed that the PAC significantly decreased the performance degradation in unsupervised adaptive learning scenarios compared with NSVC (9.03% ± 2.23%, p < 0.05) and ISVC (13.38% ± 2.62%, p = 0.001), and reduced the retraining time cost compared with ISVC (2 ms per updating cycle vs. 50 ms per updating cycle).

Crucial role of strategy updating for coexistence of strategies in interaction networks.

PubMed

Zhang, Jianlei; Zhang, Chunyan; Cao, Ming; Weissing, Franz J

2015-04-01

Network models are useful tools for studying the dynamics of social interactions in a structured population. After a round of interactions with the players in their local neighborhood, players update their strategy based on the comparison of their own payoff with the payoff of one of their neighbors. Here we show that the assumptions made on strategy updating are of crucial importance for the strategy dynamics. In the first step, we demonstrate that seemingly small deviations from the standard assumptions on updating have major implications for the evolutionary outcome of two cooperation games: cooperation can more easily persist in a Prisoner's Dilemma game, while it can go more easily extinct in a Snowdrift game. To explain these outcomes, we develop a general model for the updating of states in a network that allows us to derive conditions for the steady-state coexistence of states (or strategies). The analysis reveals that coexistence crucially depends on the number of agents consulted for updating. We conclude that updating rules are as important for evolution on a network as network structure and the nature of the interaction.

Crucial role of strategy updating for coexistence of strategies in interaction networks

NASA Astrophysics Data System (ADS)

Zhang, Jianlei; Zhang, Chunyan; Cao, Ming; Weissing, Franz J.

2015-04-01

Network models are useful tools for studying the dynamics of social interactions in a structured population. After a round of interactions with the players in their local neighborhood, players update their strategy based on the comparison of their own payoff with the payoff of one of their neighbors. Here we show that the assumptions made on strategy updating are of crucial importance for the strategy dynamics. In the first step, we demonstrate that seemingly small deviations from the standard assumptions on updating have major implications for the evolutionary outcome of two cooperation games: cooperation can more easily persist in a Prisoner's Dilemma game, while it can go more easily extinct in a Snowdrift game. To explain these outcomes, we develop a general model for the updating of states in a network that allows us to derive conditions for the steady-state coexistence of states (or strategies). The analysis reveals that coexistence crucially depends on the number of agents consulted for updating. We conclude that updating rules are as important for evolution on a network as network structure and the nature of the interaction.

Applying the Analytic Hierarchy Process to Oil Sands Environmental Compliance Risk Management

NASA Astrophysics Data System (ADS)

Roux, Izak Johannes, III

Oil companies in Alberta, Canada, invested $32 billion on new oil sands projects in 2013. Despite the size of this investment, there is a demonstrable deficiency in the uniformity and understanding of environmental legislation requirements that manifest into increased project compliance risks. This descriptive study developed 2 prioritized lists of environmental regulatory compliance risks and mitigation strategies and used multi-criteria decision theory for its theoretical framework. Information from compiled lists of environmental compliance risks and mitigation strategies was used to generate a specialized pairwise survey, which was piloted by 5 subject matter experts (SMEs). The survey was validated by a sample of 16 SMEs, after which the Analytic Hierarchy Process (AHP) was used to rank a total of 33 compliance risks and 12 mitigation strategy criteria. A key finding was that the AHP is a suitable tool for ranking of compliance risks and mitigation strategies. Several working hypotheses were also tested regarding how SMEs prioritized 1 compliance risk or mitigation strategy compared to another. The AHP showed that regulatory compliance, company reputation, environmental compliance, and economics ranked the highest and that a multi criteria mitigation strategy for environmental compliance ranked the highest. The study results will inform Alberta oil sands industry leaders about the ranking and utility of specific compliance risks and mitigations strategies, enabling them to focus on actions that will generate legislative and public trust. Oil sands leaders implementing a risk management program using the risks and mitigation strategies identified in this study will contribute to environmental conservation, economic growth, and positive social change.

Boosting cooperation by involving extortion in spatial prisoner's dilemma games

NASA Astrophysics Data System (ADS)

Wu, Zhi-Xi; Rong, Zhihai

2014-12-01

We study the evolution of cooperation in spatial prisoner's dilemma games with and without extortion by adopting the aspiration-driven strategy updating rule. We focus explicitly on how the strategy updating manner (whether synchronous or asynchronous) and also the introduction of extortion strategy affect the collective outcome of the games. By means of Monte Carlo simulations as well as dynamical cluster techniques, we find that the involvement of extortioners facilitates the boom of cooperators in the population (and whom can always dominate the population if the temptation to defect is not too large) for both synchronous and asynchronous strategy updating, in stark contrast to the other case, where cooperation is promoted for an intermediate aspiration level with synchronous strategy updating, but is remarkably inhibited if the strategy updating is implemented asynchronously. We explain the results by configurational analysis and find that the presence of extortion leads to the checkerboard-like ordering of cooperators and extortioners, which enable cooperators to prevail in the population with both strategy updating manners. Moreover, extortion itself is evolutionary stable, and therefore acts as the incubator for the evolution of cooperation.

Computer system design description for SY-101 hydrogen mitigation test project data acquisition and control system (DACS-1)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ermi, A.M.

1997-05-01

Description of the Proposed Activity/REPORTABLE OCCURRENCE or PIAB: This ECN changes the computer systems design description support document describing the computers system used to control, monitor and archive the processes and outputs associated with the Hydrogen Mitigation Test Pump installed in SY-101. There is no new activity or procedure associated with the updating of this reference document. The updating of this computer system design description maintains an agreed upon documentation program initiated within the test program and carried into operations at time of turnover to maintain configuration control as outlined by design authority practicing guidelines. There are no new crediblemore » failure modes associated with the updating of information in a support description document. The failure analysis of each change was reviewed at the time of implementation of the Systems Change Request for all the processes changed. This document simply provides a history of implementation and current system status.« less

The Human Space Life Sciences Critical Path Roadmap Project: A Strategy for Human Space Flight through Exploration-Class Missions

NASA Technical Reports Server (NTRS)

Sawin, Charles F.

1999-01-01

The product of the critical path roadmap project is an integrated strategy for mitigating the risks associated with human exploration class missions. It is an evolving process that will assure the ability to communicate the integrated critical path roadmap. Unlike previous reports, this one will not sit on a shelf - it has the full support of the JSC Space and Life Sciences Directorate (SA) and is already being used as a decision making tool (e.g., budget and investigation planning for Shuttle and Space Station mission). Utility of this product depends on many efforts, namely: providing the required information (completed risk data sheets, critical question information, technology data). It is essential to communicate the results of the critical path roadmap to the scientific community - this meeting is a good opportunity to do so. The web site envisioned for the critical path roadmap will provide the capability to communicate to a broader community and to track and update the system routinely.

Designing, implementing and monitoring social impact mitigation strategies: Lessons from Forest Industry Structural Adjustment Packages

DOE Office of Scientific and Technical Information (OSTI.GOV)

Loxton, Edwina A., E-mail: Edwina.Loxton@anu.edu.au; Schirmer, Jacki, E-mail: Jacki.Schirmer@canberra.edu.au; Cooperative Research Centre for Forestry, Hobart, 7001

2013-09-15

Social impact mitigation strategies are implemented by the proponents of policies and projects with the intent of reducing the negative, and increasing the positive social impacts of their activities, and facilitating the achievement of policy/project goals. Evaluation of mitigation strategies is critical to improving their future success and cost-effectiveness. This paper evaluates two Forest Industry Structural Adjustment Packages (FISAP) implemented in Australia in the 1990s to 2000s as part of broader policy changes that reduced access to timber from publicly owned native forests. It assesses the effectiveness of the structure, design, implementation and monitoring of the FISAPs, and highlights themore » interactions between these four elements and their influence on social impacts. The two FISAPs were found to be effective in terms of reducing negative impacts, encouraging positive impacts and contributing towards policy goals, although they did not mitigate negative impacts in all cases, and sometimes interacted with external factors and additional policy changes to contribute to significant short and long term negative impacts. -- Highlights: ► Mitigation strategies aim to reduce negative and enhance positive social impacts ► Mitigation strategy design, implementation, and monitoring are critical to success ► Effective mitigation enhanced the capacity of recipients to respond to change ► Mitigation strategies influenced multiple interacting positive and negative impacts ► Success required good communication, transparency, support, resources and timing.« less

77 FR 68155 - Sunshine Act Meeting Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-15

...-Quality Control Compliance/3rd Party CPA XII. National Foreclosure Mitigation Counseling (NFMC) Compliance Update XIII. OHTS Watch List and Overview of Organizational Assessment Review Process XIV. Adjournment...

Dealing with the white death: avalanche risk management for traffic routes.

PubMed

Rheinberger, Christoph M; Bründl, Michael; Rhyner, Jakob

2009-01-01

This article discusses mitigation strategies to protect traffic routes from snow avalanches. Up to now, mitigation of snow avalanches on many roads and railways in the Alps has relied on avalanche sheds, which require large initial investments resulting in high opportunity costs. Therefore, avalanche risk managers have increasingly adopted organizational mitigation measures such as warning systems and closure policies instead. The effectiveness of these measures is, however, greatly dependent on human decisions. In this article, we present a method for optimizing avalanche mitigation for traffic routes in terms of both their risk reduction impact and their net benefit to society. First, we introduce a generic framework for assessing avalanche risk and for quantifying the impact of mitigation. This allows for sound cost-benefit comparisons between alternative mitigation strategies. Second, we illustrate the framework with a case study from Switzerland. Our findings suggest that site-specific characteristics of avalanche paths, as well as the economic importance of a traffic route, are decisive for the choice of optimal mitigation strategies. On routes endangered by few avalanche paths with frequent avalanche occurrences, structural measures are most efficient, whereas reliance on organizational mitigation is often the most appropriate strategy on routes endangered by many paths with infrequent or fuzzy avalanche risk. Finally, keeping a traffic route open may be very important for tourism or the transport industry. Hence, local economic value may promote the use of a hybrid strategy that combines organizational and structural measures to optimize the resource allocation of avalanche risk mitigation.

Mitigating amphibian chytridiomycosis in nature

USGS Publications Warehouse

Garner, Trenton W. J.; Schmidt, Benedikt R.; Martel, An; Pasmans, Frank; Muths, Erin L.; Cunningham, Andrew A.; Weldon, Che; Fisher, Matthew C.; Bosch, Jaime

2016-01-01

Amphibians across the planet face the threat of population decline and extirpation caused by the disease chytridiomycosis. Despite consensus that the fungal pathogens responsible for the disease are conservation issues, strategies to mitigate their impacts in the natural world are, at best, nascent. Reducing risk associated with the movement of amphibians, non-amphibian vectors and other sources of infection remains the first line of defence and a primary objective when mitigating the threat of disease in wildlife. Amphibian-associated chytridiomycete fungi and chytridiomycosis are already widespread, though, and we therefore focus on discussing options for mitigating the threats once disease emergence has occurred in wild amphibian populations. All strategies have shortcomings that need to be overcome before implementation, including stronger efforts towards understanding and addressing ethical and legal considerations. Even if these issues can be dealt with, all currently available approaches, or those under discussion, are unlikely to yield the desired conservation outcome of disease mitigation. The decision process for establishing mitigation strategies requires integrated thinking that assesses disease mitigation options critically and embeds them within more comprehensive strategies for the conservation of amphibian populations, communities and ecosystems.

Disease Risk Mitigation: The Equivalence of Two Selective Mixing Strategies on Aggregate Contact Patterns & Resulting Epidemic Spread☆

PubMed Central

Morin, Benjamin R; Perrings, Charles; Levin, Simon; Kinzig, Ann

2014-01-01

The personal choices affecting the transmission of infectious diseases include the number of contacts an individual makes, and the risk-characteristics of those contacts. We consider whether these different choices have distinct implications for the course of an epidemic. We also consider whether choosing contact mitigation (how much to mix) and affinity mitigation (with whom to mix) strategies together has different epidemiological effects than choosing each separately. We use a set of differential equation compartmental models of the spread of disease, coupled with a model of selective mixing. We assess the consequences of varying contact or affinity mitigation as a response to disease risk. We do this by comparing disease incidence and dynamics under varying contact volume, contact type, and both combined across several different disease models. Specifically, we construct a change of variables that allows one to transition from contact mitigation to affinity mitigation, and vice versa. In the absence of asymptomatic infection we find no difference in the epidemiological impacts of the two forms of disease risk mitigation. Furthermore, since models that include both mitigation strategies are under-determined, varying both results in no outcome that could not be reached by choosing either separately. Which strategy is actually chosen then depends not on their epidemiological consequences, but on the relative cost of reducing contact volume versus altering contact type. Although there is no fundamental epidemiological difference between the two forms of mitigation, the social cost of alternative strategies can be very different. From a social perspective, therefore, whether one strategy should be promoted over another depends on economic not epidemiological factors. PMID:25150459

Disease risk mitigation: the equivalence of two selective mixing strategies on aggregate contact patterns and resulting epidemic spread.

PubMed

Morin, Benjamin R; Perrings, Charles; Levin, Simon; Kinzig, Ann

2014-12-21

The personal choices affecting the transmission of infectious diseases include the number of contacts an individual makes, and the risk-characteristics of those contacts. We consider whether these different choices have distinct implications for the course of an epidemic. We also consider whether choosing contact mitigation (how much to mix) and affinity mitigation (with whom to mix) strategies together has different epidemiological effects than choosing each separately. We use a set of differential equation compartmental models of the spread of disease, coupled with a model of selective mixing. We assess the consequences of varying contact or affinity mitigation as a response to disease risk. We do this by comparing disease incidence and dynamics under varying contact volume, contact type, and both combined across several different disease models. Specifically, we construct a change of variables that allows one to transition from contact mitigation to affinity mitigation, and vice versa. In the absence of asymptomatic infection we find no difference in the epidemiological impacts of the two forms of disease risk mitigation. Furthermore, since models that include both mitigation strategies are underdetermined, varying both results in no outcome that could not be reached by choosing either separately. Which strategy is actually chosen then depends not on their epidemiological consequences, but on the relative cost of reducing contact volume versus altering contact type. Although there is no fundamental epidemiological difference between the two forms of mitigation, the social cost of alternative strategies can be very different. From a social perspective, therefore, whether one strategy should be promoted over another depends on economic not epidemiological factors. Copyright © 2014 Elsevier Ltd. All rights reserved.

Vernacular design based on sustainable disaster's mitigation communication and education strategy

NASA Astrophysics Data System (ADS)

Mansoor, Alvanov Zpalanzani

2015-04-01

Indonesia is located between three active tectonic plates, which are prone to natural disasters such as earthquake, volcanic eruption, and also giant tidal wave-tsunami. Adequate infrastructure plays an important role in disaster mitigation, yet without good public awareness, the mitigation process won't be succeeded. The absence of awareness can lead to infrastructure mistreatment. Several reports on lack of understanding or misinterpretation of disaster mitigation especially from rural and coastal communities need to be solved, especially from communication aspects. This is an interdisciplinary study on disaster mitigation communication design and education strategy from visual communication design studies paradigm. This paper depicts research results which applying vernacular design base to elaborate sustainable mitigation communication and education strategy on various visual media and social campaigns. This paper also describes several design approaches which may becomes way to elaborate sustainable awareness and understanding on disaster mitigation among rural and coastal communities in Indonesia.

Vapor Intrusion Assessment and Mitigation 2012

DTIC Science & Technology

2012-03-26

1 Geosyntec 0 consultants Vapor Intrusion Assessment and Mitigation 2012 Robert Ettinger, M.S., P.E., Todd McAiary, M.Sc., P.Eng., P.G...REPORT DATE 26 MAR 2012 2. REPORT TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Vapor Intrusion Assessment and...Updates • Typical Assessment Approaches and Common Challenges • Methods to Distinguish Background Sources (McHugh) • Significance • Compound

Advanced insider threat mitigation workshop instructional materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gibbs, Philip; Larsen, Robert; O Brien, Mike

Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt and protracted theft of nuclear materials. This particular set of materials is a n update of a January 2008 version to add increased emphasis on Material Control and Accounting and its role with respect to protracted insider nuclear material theft scenarios.

Sensitivity of climate mitigation strategies to natural disturbances

DOE Office of Scientific and Technical Information (OSTI.GOV)

Le Page, Yannick LB; Hurtt, George; Thomson, Allison M.

2013-02-19

The present and future concentration of atmospheric carbon dioxide depends on both anthropogenic and natural sources and sinks of carbon. Most proposed climate mitigation strategies rely on a progressive transition to carbon12 efficient technologies to reduce industrial emissions, substantially supported by policies to maintain or enhance the terrestrial carbon stock in forests and other ecosystems. This strategy may be challenged if terrestrial sequestration capacity is affected by future climate feedbacks, but how and to what extent is little understood. Here, we show that climate mitigation strategies are highly sensitive to future natural disturbance rates (e.g. fires, hurricanes, droughts), because ofmore » potential effect of disturbances on the terrestrial carbon balance. Generally, altered disturbance rates affect the pace of societal and technological transitions required to achieve the mitigation target, with substantial consequences on the energy sector and on the global economy. Understanding the future dynamics and consequences of natural disturbances on terrestrial carbon balance is thus essential for developing robust climate mitigation strategies and policies« less

The Moving Target of Climate Mitigation: Examples from the Energy Sector in California

NASA Astrophysics Data System (ADS)

Tarroja, B.; AghaKouchak, A.; Forrest, K.; Chiang, F.; Samuelsen, S.

2016-12-01

In response to the concerns of climate change-induced impacts on human health, environmental integrity, and the secure operation of resource supply infrastructures, strategies to reduce greenhouse gas (GHG) emissions of major societal sectors have been in development. In the energy sector, these strategies are based in low carbon primary energy deployment, increased energy efficiency, and implementing complementary technologies for operational resilience. While these strategies are aimed at climate mitigation, a degree of climate change-induced impacts will occur by the time of their deployment, and many of these impacts can compromise the effectiveness of these climate mitigation strategies. In order to develop climate mitigation strategies that will achieve their GHG reduction and other goals, the impact that climate change-induced conditions can have on different components of climate mitigation strategies must be understood. This presentation will highlight three examples of how climate change-induced conditions affect components of climate mitigation strategies in California: through impacts on 1) hydropower generation, 2) renewable potential for geothermal and solar thermal resources to form part of the renewable resource portfolio, and 3) the magnitudes and shapes of the electric load demand that must be met sustainably. These studies are part of a larger, overarching project to understand how climate change impacts the energy system and how to develop a sustainable energy infrastructure that is resilient against these impacts.

Modeling nexus of urban heat island mitigation strategies with electricity/power usage and consumer costs: a case study for Phoenix, Arizona, USA

NASA Astrophysics Data System (ADS)

Silva, Humberto; Fillpot, Baron S.

2018-01-01

A reduction in both power and electricity usage was determined using a previously validated zero-dimensional energy balance model that implements mitigation strategies used to reduce the urban heat island (UHI) effect. The established model has been applied to show the change in urban characteristic temperature when executing four common mitigation strategies: increasing the overall (1) emissivity, (2) vegetated area, (3) thermal conductivity, and (4) albedo of the urban environment in a series of increases by 5, 10, 15, and 20% from baseline values. Separately, a correlation analysis was performed involving meteorological data and total daily energy (TDE) consumption where the 24-h average temperature was shown to have the greatest correlation to electricity service data in the Phoenix, Arizona, USA, metropolitan region. A methodology was then developed for using the model to predict TDE consumption reduction and corresponding cost-saving analysis when implementing the four mitigation strategies. The four modeled UHI mitigation strategies, taken in combination, would lead to the largest percent reduction in annual energy usage, where increasing the thermal conductivity is the single most effective mitigation strategy. The single least effective mitigation strategy, increasing the emissivity by 5% from the baseline value, resulted in an average calculated reduction of about 1570 GWh in yearly energy usage with a corresponding 157 million dollar cost savings. When the four parameters were increased in unison by 20% from baseline values, an average calculated reduction of about 2050 GWh in yearly energy usage was predicted with a corresponding 205 million dollar cost savings.

Community Mitigation Guidelines to Prevent Pandemic Influenza — United States, 2017

PubMed Central

Levitt, Alexandra; Kanade, Neha; Wright-Jegede, Narue; Dopson, Stephanie; Biggerstaff, Matthew; Reed, Carrie; Uzicanin, Amra; Levitt, Alexandra; Dopson, Stephanie; Frank, Mark; Holloway, Rachel; Koonin, Lisa; Rasmussen, Sonja; Redd, Stephen; de la Motte Hurst, Christopher; Kanade, Neha; Rainey, Jeanette; Uzicanin, Amra; Biggerstaff, Matthew; Jernigan, Daniel; Reed, Carrie

2017-01-01

Summary When a novel influenza A virus with pandemic potential emerges, nonpharmaceutical interventions (NPIs) often are the most readily available interventions to help slow transmission of the virus in communities, which is especially important before a pandemic vaccine becomes widely available. NPIs, also known as community mitigation measures, are actions that persons and communities can take to help slow the spread of respiratory virus infections, including seasonal and pandemic influenza viruses. These guidelines replace the 2007 Interim Pre-pandemic Planning Guidance: Community Strategy for Pandemic Influenza Mitigation in the United States — Early, Targeted, Layered Use of Nonpharmaceutical Interventions (https://stacks.cdc.gov/view/cdc/11425). Several elements remain unchanged from the 2007 guidance, which described recommended NPIs and the supporting rationale and key concepts for the use of these interventions during influenza pandemics. NPIs can be phased in, or layered, on the basis of pandemic severity and local transmission patterns over time. Categories of NPIs include personal protective measures for everyday use (e.g., voluntary home isolation of ill persons, respiratory etiquette, and hand hygiene); personal protective measures reserved for influenza pandemics (e.g., voluntary home quarantine of exposed household members and use of face masks in community settings when ill); community measures aimed at increasing social distancing (e.g., school closures and dismissals, social distancing in workplaces, and postponing or cancelling mass gatherings); and environmental measures (e.g., routine cleaning of frequently touched surfaces). Several new elements have been incorporated into the 2017 guidelines. First, to support updated recommendations on the use of NPIs, the latest scientific evidence available since the influenza A (H1N1)pdm09 pandemic has been added. Second, a summary of lessons learned from the 2009 H1N1 pandemic response is presented to underscore the importance of broad and flexible prepandemic planning. Third, a new section on community engagement has been included to highlight that the timely and effective use of NPIs depends on community acceptance and active participation. Fourth, to provide new or updated pandemic assessment and planning tools, the novel influenza virus pandemic intervals tool, the Influenza Risk Assessment Tool, the Pandemic Severity Assessment Framework, and a set of prepandemic planning scenarios are described. Finally, to facilitate implementation of the updated guidelines and to assist states and localities with prepandemic planning and decision-making, this report links to six supplemental prepandemic NPI planning guides for different community settings that are available online (https://www.cdc.gov/nonpharmaceutical-interventions). PMID:28426646

Reducing the harm in rail crashes : analysis of injury mechanisms and mitigation strategies

DOT National Transportation Integrated Search

2016-04-12

Twenty-three commuter and inter-city passenger train : accidents, which occurred over the past twenty years, have been : analyzed. The analysis has assessed the potential effectiveness : of various injury mitigation strategies. The strategies with th...

Assessment of Clmate Change Mitigation Strategies for the Road Transport Sector of India

NASA Astrophysics Data System (ADS)

Singh, N.; Mishra, T.; Banerjee, R.

2017-12-01

India is one of the fastest growing major economies of the world. It imports three quarters of its oil demand, making transport sector major contributor of greenhouse gas (GHG) emissions. 40% of oil consumption in India comes from transport sector and over 90% of energy demand is from road transport sector. This has led to serious increase in CO2 emission and concentration of air pollutants in India. According to Intergovernmental Panel on Climate Change (IPCC), transport can play a crucial role for mitigation of global greenhouse gas emissions. Therefore, assessment of appropriate mitigation policies is required for emission reduction and cost benefit potential. The present study aims to estimate CO2, SO2, PM and NOx emissions from the road transport sector for the base year (2014) and target year (2030) by applying bottom up emission inventory model. Effectiveness of different mitigation strategies like inclusion of natural gas as alternate fuel, penetration of electric vehicle as alternate vehicle, improvement of fuel efficiency and increase share of public transport is evaluated for the target year. Emission reduction achieved from each mitigation strategies in the target year (2030) is compared with the business as usual scenario for the same year. To obtain cost benefit analysis, marginal abatement cost for each mitigation strategy is estimated. The study evaluates mitigation strategies not only on the basis of emission reduction potential but also on their cost saving potential.

Mobile source air toxics mitigation measures.

DOT National Transportation Integrated Search

2013-10-01

In accordance with the Federal Highway Administration (FHWA) Interim Guidance Update on Mobile Source Air Toxic Analysis in NEPA Documents (September 30, 2009), transportation projects subject to the National Environmental Policy Act (NEPA) mus...

Vernacular design based on sustainable disaster’s mitigation communication and education strategy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mansoor, Alvanov Zpalanzani, E-mail: nova.zp@gmail.com, E-mail: alvanov@fsrd.itb.ac.id

Indonesia is located between three active tectonic plates, which are prone to natural disasters such as earthquake, volcanic eruption, and also giant tidal wave-tsunami. Adequate infrastructure plays an important role in disaster mitigation, yet without good public awareness, the mitigation process won’t be succeeded. The absence of awareness can lead to infrastructure mistreatment. Several reports on lack of understanding or misinterpretation of disaster mitigation especially from rural and coastal communities need to be solved, especially from communication aspects. This is an interdisciplinary study on disaster mitigation communication design and education strategy from visual communication design studies paradigm. This paper depictsmore » research results which applying vernacular design base to elaborate sustainable mitigation communication and education strategy on various visual media and social campaigns. This paper also describes several design approaches which may becomes way to elaborate sustainable awareness and understanding on disaster mitigation among rural and coastal communities in Indonesia.« less

Source Update Capture in Information Agents

NASA Technical Reports Server (NTRS)

Ashish, Naveen; Kulkarni, Deepak; Wang, Yao

2003-01-01

In this paper we present strategies for successfully capturing updates at Web sources. Web-based information agents provide integrated access to autonomous Web sources that can get updated. For many information agent applications we are interested in knowing when a Web source to which the application provides access, has been updated. We may also be interested in capturing all the updates at a Web source over a period of time i.e., detecting the updates and, for each update retrieving and storing the new version of data. Previous work on update and change detection by polling does not adequately address this problem. We present strategies for intelligently polling a Web source for efficiently capturing changes at the source.

Introduction to Software Product Line Adoption

DTIC Science & Technology

2005-09-01

plans • improvement suggestions • risks and mitigation strategies • progress reports • risks and mitigation strategies • adoption plan • funding ... model • organization chart • product line concept of operations (CONOPS) • marketing plan • product proposals • acquisition strategy • organization risk

An early warning system for marine storm hazard mitigation

NASA Astrophysics Data System (ADS)

Vousdoukas, M. I.; Almeida, L. P.; Pacheco, A.; Ferreira, O.

2012-04-01

The present contribution presents efforts towards the development of an operational Early Warning System for storm hazard prediction and mitigation. The system consists of a calibrated nested-model train which consists of specially calibrated Wave Watch III, SWAN and XBeach models. The numerical simulations provide daily forecasts of the hydrodynamic conditions, morphological change and overtopping risk at the area of interest. The model predictions are processed by a 'translation' module which is based on site-specific Storm Impact Indicators (SIIs) (Ciavola et al., 2011, Storm impacts along European coastlines. Part 2: lessons learned from the MICORE project, Environmental Science & Policy, Vol 14), and warnings are issued when pre-defined threshold values are exceeded. For the present site the selected SIIs were (i) the maximum wave run-up height during the simulations; and (ii) the dune-foot horizontal retreat at the end of the simulations. Both SIIs and pre-defined thresholds were carefully selected on the grounds of existing experience and field data. Four risk levels were considered, each associated with an intervention approach, recommended to the responsible coastal protection authority. Regular updating of the topography/bathymetry is critical for the performance of the storm impact forecasting, especially when there are significant morphological changes. The system can be extended to other critical problems, like implications of global warming and adaptive management strategies, while the approach presently followed, from model calibration to the early warning system for storm hazard mitigation, can be applied to other sites worldwide, with minor adaptations.

Age-related differences in strategy knowledge updating: blocked testing produces greater improvements in metacognitive accuracy for younger than older adults.

PubMed

Price, Jodi; Hertzog, Christopher; Dunlosky, John

2008-09-01

Age-related differences in updating knowledge about strategy effectiveness after task experience have not been consistently found, perhaps because the magnitude of observed knowledge updating has been rather meager for both age groups. We examined whether creating homogeneous blocks of recall tests based on two strategies used at encoding (imagery and repetition) would enhance people's learning about strategy effects on recall. Younger and older adults demonstrated greater knowledge updating (as measured by questionnaire ratings of strategy effectiveness and by global judgments of performance) with blocked (versus random) testing. The benefit of blocked testing for absolute accuracy of global predictions was smaller for older than younger adults. However, individual differences in correlations of strategy effectiveness ratings and postdictions showed similar upgrades for both age groups. Older adults learn about imagery's superior effectiveness but do not accurately estimate the magnitude of its benefit, even after blocked testing.

The Methane to Markets Coal Mine Methane Subcommittee meeting

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2008-07-01

The presentations (overheads/viewgraphs) include: a report from the Administrative Support Group; strategy updates from Australia, India, Italy, Mexico, Nigeria, Poland and the USA; coal mine methane update and IEA's strategy and activities; the power of VAM - technology application update; the emissions trading market; the voluntary emissions reduction market - creating profitable CMM projects in the USA; an Italian perspective towards a zero emission strategies; and the wrap-up and summary.

75 FR 60133 - Detroit Area Maritime Security Committee (AMSC); Vacancies

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-29

... (threats, vulnerabilities, and consequences); Determining mitigation strategies and implementation methods... consequences and vulnerabilities, how they may change over time, and what additional mitigation strategies can...

Dust and soiling issues and impacts relating to solar energy systems: Literature review update for 2012–2015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Costa, Suellen C. S.; Diniz, Antonia Sonia A. C.; Kazmerski, Lawrence L.

The purpose of this review survey is to provide a literature compilation, updating materials reported in several review papers on solar-device soiling and mitigation approaches published over the past 5 years. The focus is on the period 2013-2015, but an updated listing is also provided for the year 2012 for completeness. This literature review also provides the first update for a periodic, single collation report on such publications proposed in this journal two years ago. This review presents a listing of the publications, their publication source, and some brief tabulated information to help guide the reader into the focus ofmore » each of the works.« less

Evolving learning rules and emergence of cooperation in spatial prisoner's dilemma.

PubMed

Moyano, Luis G; Sánchez, Angel

2009-07-07

In the evolutionary Prisoner's dilemma (PD) game, agents play with each other and update their strategies in every generation according to some microscopic dynamical rule. In its spatial version, agents do not play with every other but, instead, interact only with their neighbours, thus mimicking the existing of a social or contact network that defines who interacts with whom. In this work, we explore evolutionary, spatial PD systems consisting of two types of agents, each with a certain update (reproduction, learning) rule. We investigate two different scenarios: in the first case, update rules remain fixed for the entire evolution of the system; in the second case, agents update both strategy and update rule in every generation. We show that in a well-mixed population the evolutionary outcome is always full defection. We subsequently focus on two-strategy competition with nearest-neighbour interactions on the contact network and synchronised update of strategies. Our results show that, for an important range of the parameters of the game, the final state of the system is largely different from that arising from the usual setup of a single, fixed dynamical rule. Furthermore, the results are also very different if update rules are fixed or evolve with the strategies. In these respect, we have studied representative update rules, finding that some of them may become extinct while others prevail. We describe the new and rich variety of final outcomes that arise from this co-evolutionary dynamics. We include examples of other neighbourhoods and asynchronous updating that confirm the robustness of our conclusions. Our results pave the way to an evolutionary rationale for modelling social interactions through game theory with a preferred set of update rules.

[Lessons learned from a distribution incident at the Alps-Mediterranean Division of the French Blood Establishment].

PubMed

Legrand, D

2008-11-01

The Alps-Mediterranean division of the French blood establishment (EFS Alpes-Mediterranée) has implemented a risk management program. Within this framework, the labile blood product distribution process was assessed to identify critical steps. Subsequently, safety measures were instituted including computer-assisted decision support, detailed written instructions and control checks at each step. Failure of these measures to prevent an incident underlines the vulnerability of the process to the human factor. Indeed root cause analysis showed that the incident was due to underestimation of the danger by one individual. Elimination of this type of risk will require continuous training, testing and updating of personnel. Identification and reporting of nonconformities will allow personnel at all levels (local, regional, and national) to share lessons and implement appropriate risk mitigation strategies.

33 CFR 103.310 - Responsibilities of the Area Maritime Security (AMS) Committee.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (threats, vulnerabilities, and consequences); (3) Determine mitigation strategies and implementation... consequences and vulnerabilities, how they may change over time, and what additional mitigation strategies can...

Geography Teachers and Climate Change: Emotions about Consequences, Coping Strategies, and Views on Mitigation

ERIC Educational Resources Information Center

Hermans, Mikaela

2016-01-01

It has been indicated that teachers' emotions about climate change and their views on mitigation influence their instruction and students' engagement in mitigation actions. The aim of the study is to explore Finnish secondary geography teachers' emotions about the consequences of climate change, their strategies for coping with these emotions, and…

NASA ESTO Lidar Technologies Investment Strategy: 2016 Decadal Update

NASA Technical Reports Server (NTRS)

Valinia, Azita; Komar, George J.; Tratt, David M.; Lotshaw, William T.; Gaab, Kevin M.

2016-01-01

The NASA Earth Science Technology Office (ESTO) recently updated its investment strategy in the area of lidar technologies as it pertains to NASA's Earth Science measurement goals in the next decade. The last ESTO lidar strategy was documented in 2006. The current (2016) report assesses the state-of-the-art in lidar technologies a decade later. Lidar technology maturation in the past decade has been evaluated, and the ESTO investment strategy is updated and laid out in this report according to current NASA Earth science measurement needs and new emerging technologies.

NASA ESTO Lidar Technologies Investment Strategy: 2016 Decadal Update

NASA Technical Reports Server (NTRS)

Valinia, Azita; Komar, George J.; Tratt, David M.; Lotshaw, William; Gaab, Kevin; Mayo, David

2016-01-01

The NASA Earth Science Technology Office (ESTO) recently updated its investment strategy in the area of lidar technologies as it pertains to NASAs Earth Science measurement goals in the next decade. The last ESTO lidar strategy was documented in 2006. The current (2016) report assesses the state-of-the-art in lidar technologies a decade later. Lidar technology maturation in the past decade has been evaluated, and the ESTO investment strategy is updated and laid out in this report according to current NASA Earth science measurement needs and new emerging technologies.

NASA ESTO Lidar Technologies Investment Strategy: 2016 Decadal Update

NASA Technical Reports Server (NTRS)

Valinia, Azita; Komar, George J.; Tratt, David M.; Lotshaw, William T.; Gaab, Kevin M.

2017-01-01

The NASA Earth Science Technology Office (ESTO) recently updated its investment strategy in the area of lidar technologies as it pertains to NASA's Earth Science measurement goals in the next decade. The last ESTO lidar strategy was documented in 2006. The current (2016) report assesses the state-of-the-art in lidar technologies a decade later. Lidar technology maturation in the past decade has been evaluated, and the ESTO investment strategy is updated and laid out in this report according to current NASA Earth science measurement needs and new emerging technologies.

Common Risk Criteria Standards for National Test Ranges

DTIC Science & Technology

2016-08-01

mitigation is a national policy goal. The most recent National Space Policy of the United States (dated June 28, 2010) states that “the United States will...pursue the following goals in its national space programs …strengthening measures to mitigate orbital debris.”5 While DoD Directive (DoDD) 3100.106... United States of America. National Space Policy of the United States of America. 28 June, 2010. May be superseded by update. Retrieved 7 April 2016

Safety equipment list for the 241-SY-101 RAPID mitigation project

DOE Office of Scientific and Technical Information (OSTI.GOV)

MORRIS, K.L.

1999-06-29

This document provides the safety classification for the safety (safety class and safety RAPID Mitigation Project. This document is being issued as the project SEL until the supporting authorization basis documentation, this document will be superseded by the TWRS SEL (LMHC 1999), documentation istlralized. Upon implementation of the authorization basis significant) structures, systems, and components (SSCS) associated with the 241-SY-1O1 which will be updated to include the information contained herein.

The Roadmap to Climate Stability Based on IPCC Fifth Assessment Climate Accounting Protocols

NASA Astrophysics Data System (ADS)

Schultz, T.

2016-12-01

The Climate Stabilization Council recognizes the severe impact consequences of a rapidly warming climate and the challenging mitigation requirements of reaching the COP21 aspirational goal of +1.5°C. To address this challenge, we have used the IPCC Fifth Assessment Report which presents new methods for projecting increases in average global temperature and new metrics to update global climate accounting protocols. The updated protocols allow us to assess the full spectrum of climate mitigation projects available and identify the ability of specific projects to achieve various climate warming targets at different points in time. This assessment demonstrates the need to continue focusing on reducing and removing the major sources of overall excess heat linked to CO2, methane, black carbon, and tropospheric ozone. These findings also highlight the importance of solar radiation management (SRM) and earth radiation management (ERM) to achieve climate stabilization in the near-term. By integrating advanced life-cycle assessment (LCA) into the protocols, unintended environmental or human health impact trade-offs that may be associated with deployment of specific mitigation options can be identified. These protocols have also been introduced for standardization to the international ISO 14000 process. We conclude by describing the Climate Stabilization Council's role in establishing a platform for the scientific research, evaluation, and implementation of the identified climate mitigation projects.

Aspiration dynamics in structured population acts as if in a well-mixed one.

PubMed

Du, Jinming; Wu, Bin; Wang, Long

2015-01-26

Understanding the evolution of human interactive behaviors is important. Recent experimental results suggest that human cooperation in spatial structured population is not enhanced as predicted in previous works, when payoff-dependent imitation updating rules are used. This constraint opens up an avenue to shed light on how humans update their strategies in real life. Studies via simulations show that, instead of comparison rules, self-evaluation driven updating rules may explain why spatial structure does not alter the evolutionary outcome. Though inspiring, there is a lack of theoretical result to show the existence of such evolutionary updating rule. Here we study the aspiration dynamics, and show that it does not alter the evolutionary outcome in various population structures. Under weak selection, by analytical approximation, we find that the favored strategy in regular graphs is invariant. Further, we show that this is because the criterion under which a strategy is favored is the same as that of a well-mixed population. By simulation, we show that this holds for random networks. Although how humans update their strategies is an open question to be studied, our results provide a theoretical foundation of the updating rules that may capture the real human updating rules.

Mitigating amphibian chytridiomycoses in nature.

PubMed

Garner, Trenton W J; Schmidt, Benedikt R; Martel, An; Pasmans, Frank; Muths, Erin; Cunningham, Andrew A; Weldon, Che; Fisher, Matthew C; Bosch, Jaime

2016-12-05

Amphibians across the planet face the threat of population decline and extirpation caused by the disease chytridiomycosis. Despite consensus that the fungal pathogens responsible for the disease are conservation issues, strategies to mitigate their impacts in the natural world are, at best, nascent. Reducing risk associated with the movement of amphibians, non-amphibian vectors and other sources of infection remains the first line of defence and a primary objective when mitigating the threat of disease in wildlife. Amphibian-associated chytridiomycete fungi and chytridiomycosis are already widespread, though, and we therefore focus on discussing options for mitigating the threats once disease emergence has occurred in wild amphibian populations. All strategies have shortcomings that need to be overcome before implementation, including stronger efforts towards understanding and addressing ethical and legal considerations. Even if these issues can be dealt with, all currently available approaches, or those under discussion, are unlikely to yield the desired conservation outcome of disease mitigation. The decision process for establishing mitigation strategies requires integrated thinking that assesses disease mitigation options critically and embeds them within more comprehensive strategies for the conservation of amphibian populations, communities and ecosystems.This article is part of the themed issue 'Tackling emerging fungal threats to animal health, food security and ecosystem resilience'. © 2016 The Author(s).

Mitigating amphibian chytridiomycoses in nature

PubMed Central

Martel, An; Pasmans, Frank; Muths, Erin; Cunningham, Andrew A.; Weldon, Che; Bosch, Jaime

2016-01-01

Amphibians across the planet face the threat of population decline and extirpation caused by the disease chytridiomycosis. Despite consensus that the fungal pathogens responsible for the disease are conservation issues, strategies to mitigate their impacts in the natural world are, at best, nascent. Reducing risk associated with the movement of amphibians, non-amphibian vectors and other sources of infection remains the first line of defence and a primary objective when mitigating the threat of disease in wildlife. Amphibian-associated chytridiomycete fungi and chytridiomycosis are already widespread, though, and we therefore focus on discussing options for mitigating the threats once disease emergence has occurred in wild amphibian populations. All strategies have shortcomings that need to be overcome before implementation, including stronger efforts towards understanding and addressing ethical and legal considerations. Even if these issues can be dealt with, all currently available approaches, or those under discussion, are unlikely to yield the desired conservation outcome of disease mitigation. The decision process for establishing mitigation strategies requires integrated thinking that assesses disease mitigation options critically and embeds them within more comprehensive strategies for the conservation of amphibian populations, communities and ecosystems. This article is part of the themed issue ‘Tackling emerging fungal threats to animal health, food security and ecosystem resilience’. PMID:28080996

White House and agencies focus on space weather concerns

NASA Astrophysics Data System (ADS)

Showstack, Randy

2012-06-01

"Space weather is a serious matter that can affect human economies around the world," Tamara Dickinson, a senior policy analyst with the White House Office of Science and Technology Policy (OSTP), told attendees at the 2012 Space Weather Enterprise Forum, held 5 June in Washington, D. C. With the 2013 solar maximum nearing, researchers and government agencies are focusing on how the greater solar activity could affect our increasingly technological society and what measures can be taken to help prevent or mitigate any threats to the electricity grid, GPS, and other potentially vulnerable technologies. Dickenson said that there has been an increased awareness about space weather in the White House and that President Barack Obama recently has requested briefing memos on the topic. She highlighted several efforts the administration is taking related to space weather, including a forthcoming national Earth observation strategy, which could be released in July and will include an assessment of space weather. She explained that the strategy document will be part of the fiscal year 2014 presidential budget request and that it will be updated every 3 years.

Nitrification in agricultural soils: impact, actors and mitigation.

PubMed

Beeckman, Fabian; Motte, Hans; Beeckman, Tom

2018-04-01

Nitrogen is one of the most important nutrients for plant growth and hence heavily applied in agricultural systems via fertilization. Nitrification, that is, the conversion of ammonium via nitrite to nitrate by soil microorganisms, however, leads to nitrate leaching and gaseous nitrous oxide production and as such to an up to 50% loss of nitrogen availability for the plant. Nitrate leaching also results in eutrophication of groundwater, drinking water and recreational waters, toxic algal blooms and biodiversity loss, while nitrous oxide is a greenhouse gas with a global warming potential 300× greater than carbon dioxide. Logically, inhibition of nitrification is an important strategy used in agriculture to reduce nitrogen losses, and contributes to a more environmental-friendly practice. However, recently identified and crucial players in nitrification, that is, ammonia-oxidizing archaea and comammox bacteria, seem to be under-investigated in this respect. In this review, we give an update on the different pathways in ammonia oxidation, the relevance for agriculture and the interaction with nitrification inhibitors. As such, we hope to pinpoint possible strategies to optimize the efficiency of nitrification inhibition. Copyright © 2018 Elsevier Ltd. All rights reserved.

44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.

Code of Federal Regulations, 2012 CFR

2012-10-01

... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...

44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.

Code of Federal Regulations, 2014 CFR

2014-10-01

... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...

44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.

Code of Federal Regulations, 2011 CFR

2011-10-01

... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...

44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.

Code of Federal Regulations, 2013 CFR

2013-10-01

... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...

Effects of Orbital Lifetime Reduction on the Long-Term Earth Satellite Population as Modeled by EVOLVE 4.0

NASA Technical Reports Server (NTRS)

Krisko, Paula H.; Opiela, John N.; Liou, Jer-Chyi; Anz-Meador, Phillip D.; Theall, Jeffrey R.

1999-01-01

The latest update of the NASA orbital debris environment model, EVOLVE 4.0, has been used to study the effect of various proposed debris mitigation measures, including the NASA 25-year guideline. EVOLVE 4.0, which includes updates of the NASA breakup, solar activity, and the orbit propagator models, a GEO analysis option, and non-fragmentation debris source models, allows for the statistical modeling and predicted growth of the particle population >1 mm in characteristic length in LEO and GEO orbits. The initial implementation of this &odel has been to study the sensitivity of the overall LEO debris environment to mitigation measures designed to limit the lifetime of intact objects in LEO orbits. The mitigation measures test matrix for this study included several commonly accepted testing schemes, i.e., the variance of the maximum LEO lifetime from 10 to 50 years, the date of the initial implementation of this policy, the shut off of all explosions at some specified date, and the inclusion of disposal orbits. All are timely studies in that all scenarios have been suggested by researchers and satellite operators as options for the removal of debris from LEO orbits.

The Impacts of Climate Change Mitigation Strategies on Animal Welfare

PubMed Central

Shields, Sara; Orme-Evans, Geoffrey

2015-01-01

Simple Summary Climate change is probably the most important environmental issue of our time. Raising animals for food contributes to the production of greenhouse gases implicated in the global warming that is causing climate change. To combat this ecological disaster, a number of mitigation strategies involving changes to agricultural practices have been proposed. However, some of these changes will impact the welfare of farmed animals. This paper reviews selected climate change mitigation strategies and explains how different approaches could have negative or positive effects. Abstract The objective of this review is to point out that the global dialog on reducing greenhouse gas emissions in animal agriculture has, thus far, not adequately considered animal welfare in proposed climate change mitigation strategies. Many suggested approaches for reducing emissions, most of which could generally be described as calls for the intensification of production, can have substantial effects on the animals. Given the growing world-wide awareness and concern for animal welfare, many of these approaches are not socially sustainable. This review identifies the main emission abatement strategies in the climate change literature that would negatively affect animal welfare and details the associated problems. Alternative strategies are also identified as possible solutions for animal welfare and climate change, and it is suggested that more attention be focused on these types of options when allocating resources, researching mitigation strategies, and making policy decisions on reducing emissions from animal agriculture. PMID:26479240

The impact of distraction mitigation strategies on driving performance.

PubMed

Donmez, Birsen; Boyle, Linda Ng; Lee, John D

2006-01-01

An experiment was conducted to assess the effects of distraction mitigation strategies on drivers' performance and productivity while engaged in an in-vehicle information system task. Previous studies show that in-vehicle tasks undermine driver safety and there is a need to mitigate driver distraction. An advising strategy that alerts drivers to potential dangers and a locking strategy that prevents the driver from continuing the distracting task were presented to 16 middle-aged and 12 older drivers in a driving simulator in two modes (auditory, visual) and two road conditions (curves, braking events). Distraction was a problem for both age groups. Visual distractions were more detrimental than auditory ones for curve negotiation, as depicted by more erratic steering, F (6, 155) = 26.76, p < .05. Drivers did brake more abruptly under auditory distractions, but this effect was mitigated by both the advising, t (155) = 8.37, p < .05, and locking strategies, t (155) = 8.49, p < .05. The locking strategy also resulted in longer minimum time to collision for middle-aged drivers engaged in visual distractions, F (6, 138) = 2.43, p < .05. Adaptive interfaces can reduce abrupt braking on curve entries resulting from auditory distractions and can also improve the braking response for distracted drivers. These strategies can be incorporated into existing in-vehicle systems, thus mitigating the effects of distraction and improving driver performance.

Success in transmitting hazard science

NASA Astrophysics Data System (ADS)

Price, J. G.; Garside, T.

2010-12-01

Money motivates mitigation. An example of success in communicating scientific information about hazards, coupled with information about available money, is the follow-up action by local governments to actually mitigate. The Nevada Hazard Mitigation Planning Committee helps local governments prepare competitive proposals for federal funds to reduce risks from natural hazards. Composed of volunteers with expertise in emergency management, building standards, and earthquake, flood, and wildfire hazards, the committee advises the Nevada Division of Emergency Management on (1) the content of the State’s hazard mitigation plan and (2) projects that have been proposed by local governments and state agencies for funding from various post- and pre-disaster hazard mitigation programs of the Federal Emergency Management Agency. Local governments must have FEMA-approved hazard mitigation plans in place before they can receive this funding. The committee has been meeting quarterly with elected and appointed county officials, at their offices, to encourage them to update their mitigation plans and apply for this funding. We have settled on a format that includes the county’s giving the committee an overview of its infrastructure, hazards, and preparedness. The committee explains the process for applying for mitigation grants and presents the latest information that we have about earthquake hazards, including locations of nearby active faults, historical seismicity, geodetic strain, loss-estimation modeling, scenarios, and documents about what to do before, during, and after an earthquake. Much of the county-specific information is available on the web. The presentations have been well received, in part because the committee makes the effort to go to their communities, and in part because the committee is helping them attract federal funds for local mitigation of not only earthquake hazards but also floods (including canal breaches) and wildfires, the other major concerns in Nevada. Local citizens appreciate the efforts of the state officials to present the information in a public forum. The Committee’s earthquake presentations to the counties are supplemented by regular updates in the two most populous counties during quarterly meetings of the Nevada Earthquake Safety Council, generally alternating between Las Vegas and Reno. We have only 17 counties in Nevada, so we are making good progress at reaching each within a few years. The Committee is also learning from the county officials about their frustrations in dealing with the state and federal bureaucracies. Success is documented by the mitigation projects that FEMA has funded.

Far From “Just a Poke”

PubMed Central

Pillai Riddell, Rebecca; Taddio, Anna; Racine, Nicole; Asmundson, Gordon J. G.; Noel, Melanie; Chambers, Christine T.; Shah, Vibhuti

2015-01-01

Background: Vaccine injections are the most common painful needle procedure experienced throughout the lifespan. Many strategies are available to mitigate this pain; however, they are uncommonly utilized, leading to unnecessary pain and suffering. Some individuals develop a high level of fear and subsequent needle procedures are associated with significant distress. Objective: The present work is part of an update and expansion of a 2009 knowledge synthesis to include the management of vaccine-related pain across the lifespan and the treatment of individuals with high levels of needle fear. This article will provide a conceptual foundation for understanding: (a) painful procedures and their role in the development and maintenance of high levels of fear; (b) treatment strategies for preventing or reducing the experience of pain and the development of fear; and (c) interventions for mitigating high levels of fear once they are established. Results: First, the general definitions, lifespan development and functionality, needle procedure-related considerations, and assessment of the following constructs are provided: pain, fear, anxiety, phobia, distress, and vasovagal syncope. Second, the importance of unmitigated pain from needle procedures is highlighted from a developmental perspective. Third, the prevalence, course, etiology, and consequences of high levels of needle fear are described. Finally, the management of needle-related pain and fear are outlined to provide an introduction to the series of systematic reviews in this issue. Discussion: Through the body of work in this supplement, the authors aim to provide guidance in how to treat vaccination-related pain and its sequelae, including high levels of needle fear. PMID:26352920

"Southwest Strategy" update

Treesearch

Steve Kluge

1999-01-01

The Southwest Strategy is an effort by federal agencies to work with each other, the public, and tribal, state, and local agencies to maintain and restore the cultural, economic, and environmental quality of life in Arizona and New Mexico. This update explains the strategy and its progress to date.

Global potential of biospheric carbon management for climate mitigation.

PubMed

Canadell, Josep G; Schulze, E Detlef

2014-11-19

Elevated concentrations of atmospheric greenhouse gases (GHGs), particularly carbon dioxide (CO2), have affected the global climate. Land-based biological carbon mitigation strategies are considered an important and viable pathway towards climate stabilization. However, to satisfy the growing demands for food, wood products, energy, climate mitigation and biodiversity conservation-all of which compete for increasingly limited quantities of biomass and land-the deployment of mitigation strategies must be driven by sustainable and integrated land management. If executed accordingly, through avoided emissions and carbon sequestration, biological carbon and bioenergy mitigation could save up to 38 billion tonnes of carbon and 3-8% of estimated energy consumption, respectively, by 2050.

Review of Natural Phenomena Hazard (NPH) Assessments for the DOE Hanford Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snow, Robert L.; Ross, Steven B.

2011-09-15

The purpose of this review is to assess the need for updating Natural Phenomena Hazard (NPH) assessments for the DOE's Hanford Site, as required by DOE Order 420.1B Chapter IV, Natural Phenomena Hazards Mitigation, based on significant changes in state-of-the-art NPH assessment methodology or site-specific information. This review is an update and expansion to the September 2010 review of PNNL-19751, Review of Natural Phenomena Hazard (NPH) Assessments for the Hanford 200 Areas (Non-Seismic).

New Developments in Error Detection and Correction Strategies for Critical Applications

NASA Technical Reports Server (NTRS)

Berg, Melanie; LaBel, Ken

2016-01-01

The presentation will cover a variety of mitigation strategies that were developed for critical applications. An emphasis is placed on strengths and weaknesses per mitigation technique as it pertains to different FPGA device types.

Susceptibility of SCADA systems and the energy sector

NASA Astrophysics Data System (ADS)

Goike, Lindsay

The research in this paper focused on analyzing SCADA systems in the energy sector for susceptibility to cyber attacks, in furtherance of providing suggestions to mitigate current and future cyber attacks. The research will be addressing the questions: how are SCADA systems susceptible to cyber attacks, and what are the suggested ways to mitigate both current and future cyber attacks. The five main categories of security vulnerabilities facing current SCADA systems were found to be: connectivity to the Internet, failure to plan, interdependency of sectors, numerous different types of threats, and outdated software. Some of the recommendations mentioned to mitigate current and future risks were: virtual private networks, risk assessments, increased physical security, updating of software, and firewalls.

Mitigating amphibian disease: strategies to maintain wild populations and control chytridiomycosis

PubMed Central

2011-01-01

Background Rescuing amphibian diversity is an achievable conservation challenge. Disease mitigation is one essential component of population management. Here we assess existing disease mitigation strategies, some in early experimental stages, which focus on the globally emerging chytrid fungus Batrachochytrium dendrobatidis. We discuss the precedent for each strategy in systems ranging from agriculture to human medicine, and the outlook for each strategy in terms of research needs and long-term potential. Results We find that the effects of exposure to Batrachochytrium dendrobatidis occur on a spectrum from transient commensal to lethal pathogen. Management priorities are divided between (1) halting pathogen spread and developing survival assurance colonies, and (2) prophylactic or remedial disease treatment. Epidemiological models of chytridiomycosis suggest that mitigation strategies can control disease without eliminating the pathogen. Ecological ethics guide wildlife disease research, but several ethical questions remain for managing disease in the field. Conclusions Because sustainable conservation of amphibians in nature is dependent on long-term population persistence and co-evolution with potentially lethal pathogens, we suggest that disease mitigation not focus exclusively on the elimination or containment of the pathogen, or on the captive breeding of amphibian hosts. Rather, successful disease mitigation must be context specific with epidemiologically informed strategies to manage already infected populations by decreasing pathogenicity and host susceptibility. We propose population level treatments based on three steps: first, identify mechanisms of disease suppression; second, parameterize epizootiological models of disease and population dynamics for testing under semi-natural conditions; and third, begin a process of adaptive management in field trials with natural populations. PMID:21496358

Traffic congestion and reliability : trends and advanced strategies for congestion mitigation.

DOT National Transportation Integrated Search

2005-09-01

The report Traffic Congestion and Reliability: Trends and Advanced Strategies for : Congestion Mitigation provides a snapshot of congestion in the United States by : summarizing recent trends in congestion, highlighting the role of travel time : reli...

Mars Design Reference Architecture 5.0 Study: Executive Summary

NASA Technical Reports Server (NTRS)

Drake, Bret G.

2008-01-01

The NASA Mars Design Reference Architecture 5.0 Study seeks to update its long term goals and objective for human exploration missions; flight and surface systems for human missions and supporting infrastructure; operational concept for human and robotic exploration of Mars; key challenges including risk and cost drivers; and, its development schedule options. It additionally seeks to assess strategic linkages between lunar and Mars strategies and develop and understanding of methods for reducing the cost/risk of human Mars missions through investment in research, technology development, and synergy with other exploration plans. Recommendations are made regarding conjunction class (long-stay) missions which are seen as providing the best balance of cost, risk, and performance. Additionally, this study reviews entry, descent, and landing challenges; in-space transportation systems; launch vehicle and Orion assessments; risk and risk mitigation; key driving requirements and challenges; and, lunar linkages.

Spatial Updating Strategy Affects the Reference Frame in Path Integration.

PubMed

He, Qiliang; McNamara, Timothy P

2018-06-01

This study investigated how spatial updating strategies affected the selection of reference frames in path integration. Participants walked an outbound path consisting of three successive waypoints in a featureless environment and then pointed to the first waypoint. We manipulated the alignment of participants' final heading at the end of the outbound path with their initial heading to examine the adopted reference frame. We assumed that the initial heading defined the principal reference direction in an allocentric reference frame. In Experiment 1, participants were instructed to use a configural updating strategy and to monitor the shape of the outbound path while they walked it. Pointing performance was best when the final heading was aligned with the initial heading, indicating the use of an allocentric reference frame. In Experiment 2, participants were instructed to use a continuous updating strategy and to keep track of the location of the first waypoint while walking the outbound path. Pointing performance was equivalent regardless of the alignment between the final and the initial headings, indicating the use of an egocentric reference frame. These results confirmed that people could employ different spatial updating strategies in path integration (Wiener, Berthoz, & Wolbers Experimental Brain Research 208(1) 61-71, 2011), and suggested that these strategies could affect the selection of the reference frame for path integration.

A Coupled Economic and Physical Model of Coastal Adaptation and Abandonment: Are human occupied coastlines a bubble waiting to burst?

NASA Astrophysics Data System (ADS)

McNamara, D.; Keeler, A.

2011-12-01

Policy discussions of adaptation by coastal residents to increasing rates of sea level rise and changing frequency of damaging storms have focused on community land use planning processes. This view neglects the role that market dynamics and climate change expectations play in the way coastal communities choose among risk mitigation options and manage land use decisions in an environment of escalating risks. We use a model coupling physical coastal processes with an agent-based model of behavior in real estate and mitigation markets to examine the interplay of climate-driven coastal hazards, collective mitigation decisions, and individual beliefs. The physical component model simulates barrier island processes that respond to both storms and slow scale dynamics associated with sea level rise. The economic component model is an agent-based model of economic behavior where agents are rational economic actors working off different assessments of future climate-driven events. Agents differentially update their beliefs based on a) how much emphasis they give to observed coastal changes and b) how much weight they give to scientific predictions. In essence, agents differ along a spectrum of how much they believe that the past is the best guide to the future and how quickly they react to new information. We use the coupled model to explore three questions of interest to coastal policy. First, how do the interplay of costal processes, beliefs, and mitigation choices affect the level and stability of real estate prices? Second, how does this interplay affect the incentives for community investments in shoreline protection? Third, how do expectations and reactions to observed events, as well as mitigation investments, affect the built environment in circumstances when climate risks reach very high levels? This last question relates to a key aspect of climate change adaptation on the coast - when does mitigation give way to abandonment as an optimal adaptation strategy? Results suggest that subjective expectations about climate risk and about the effectiveness of mitigation in high-risk environments are critical in determining when the market starts to reflect the possibility that property might no longer be inhabitable. Results will be presented that contrast the dynamics of abandonment over a range of sea level rise and storminess scenarios.

Strategies to mitigate dissociative and psychotomimetic effects of ketamine in the treatment of major depressive episodes: a narrative review.

PubMed

Cooper, Matthew D; Rosenblat, Joshua D; Cha, Danielle S; Lee, Yena; Kakar, Ron; McIntyre, Roger S

2017-09-01

Objectives Replicated evidence has demonstrated that ketamine exerts rapid-acting and potent antidepressant effects. Notwithstanding, its promise to mitigate depressive symptoms and suicidality in antidepressant-resistant populations, several limitations and safety concerns accompany ketamine including, but not limited to, the potential for abuse and psychotomimetic/dissociative experiences. The focus of the current narrative review is to synthesise available evidence of strategies that may mitigate and fully prevent treatment-emergent psychotomimetic and dissociative effects associated with ketamine administration. Methods PubMed, Google Scholar and ClinicalTrials.gov were searched for relevant articles. Results Potential avenues investigated to minimise psychotomimetic effects associated with ketamine administration include the following: (1) altering dosing and infusion rates; (2) route of administration; (3) enantiomer choice; (4) co-administration with mood stabilisers of antipsychotics; and (5) use of alternative N-methyl-d-aspartate (NMDA)-modulating agents. Emerging evidence indicates that dissociative experiences can be significantly mitigated by using an intranasal route of administration, lower dosages, or use of alternative NMDA-modulating agents, namely lanicemine (AZD6765) and GLYX-13. Conclusions Currently, intranasal administration presents as the most promising strategy to mitigate dissociative and psychotomimetic effects; however, studies of strategies to mitigate the adverse events of ketamine are limited in number and quality and thus further investigation is still needed.

A systematic review to identify areas of enhancements of pandemic simulation models for operational use at provincial and local levels

PubMed Central

2012-01-01

Background In recent years, computer simulation models have supported development of pandemic influenza preparedness policies. However, U.S. policymakers have raised several concerns about the practical use of these models. In this review paper, we examine the extent to which the current literature already addresses these concerns and identify means of enhancing the current models for higher operational use. Methods We surveyed PubMed and other sources for published research literature on simulation models for influenza pandemic preparedness. We identified 23 models published between 1990 and 2010 that consider single-region (e.g., country, province, city) outbreaks and multi-pronged mitigation strategies. We developed a plan for examination of the literature based on the concerns raised by the policymakers. Results While examining the concerns about the adequacy and validity of data, we found that though the epidemiological data supporting the models appears to be adequate, it should be validated through as many updates as possible during an outbreak. Demographical data must improve its interfaces for access, retrieval, and translation into model parameters. Regarding the concern about credibility and validity of modeling assumptions, we found that the models often simplify reality to reduce computational burden. Such simplifications may be permissible if they do not interfere with the performance assessment of the mitigation strategies. We also agreed with the concern that social behavior is inadequately represented in pandemic influenza models. Our review showed that the models consider only a few social-behavioral aspects including contact rates, withdrawal from work or school due to symptoms appearance or to care for sick relatives, and compliance to social distancing, vaccination, and antiviral prophylaxis. The concern about the degree of accessibility of the models is palpable, since we found three models that are currently accessible by the public while other models are seeking public accessibility. Policymakers would prefer models scalable to any population size that can be downloadable and operable in personal computers. But scaling models to larger populations would often require computational needs that cannot be handled with personal computers and laptops. As a limitation, we state that some existing models could not be included in our review due to their limited available documentation discussing the choice of relevant parameter values. Conclusions To adequately address the concerns of the policymakers, we need continuing model enhancements in critical areas including: updating of epidemiological data during a pandemic, smooth handling of large demographical databases, incorporation of a broader spectrum of social-behavioral aspects, updating information for contact patterns, adaptation of recent methodologies for collecting human mobility data, and improvement of computational efficiency and accessibility. PMID:22463370

Comparative advantage strategy for rapid pollution mitigation in China.

PubMed

Xu, Yuan

2013-09-03

Due to its sheer size and growth trend, no other country is facing more daunting challenges than China in reducing its pollutant emissions. A critical but inadequately addressed question is how rapidly China could feasibly achieve such mitigation. The stake is high not only about how much worse China's environmental quality could become but also about how the world can prevent catastrophic climate change. Through examining sulfur dioxide (SO2) mitigation in coal-fired power plants and wind energy development for carbon dioxide (CO2) mitigation, this article proposes a comparative advantage strategy for overcoming high barriers to fast pollution mitigation. On the demand side, China could first make progress in the deployment of more pollution control facilities and then improve their operational performance. The resulting low technological market entry barriers could help to build enough industrial capacity to meet the huge demand with prices under control. The strategy in the current practice could be improved to establish not only a large supply industry but also a strong one to enable other countries to move more rapidly in pollution mitigation.

New Developments in Error Detection and Correction Strategies for Critical Applications

NASA Technical Reports Server (NTRS)

Berg, Melanie; Label, Ken

2017-01-01

The presentation will cover a variety of mitigation strategies that were developed for critical applications. An emphasis is placed on strengths and weaknesses per mitigation technique as it pertains to different Field programmable gate array (FPGA) device types.

Fixation of competing strategies when interacting agents differ in the time scale of strategy updating

NASA Astrophysics Data System (ADS)

Zhang, Jianlei; Weissing, Franz J.; Cao, Ming

2016-09-01

A commonly used assumption in evolutionary game theory is that natural selection acts on individuals in the same time scale; e.g., players use the same frequency to update their strategies. Variation in learning rates within populations suggests that evolutionary game theory may not necessarily be restricted to uniform time scales associated with the game interaction and strategy adaption evolution. In this study, we remove this restricting assumption by dividing the population into fast and slow groups according to the players' strategy updating frequencies and investigate how different strategy compositions of one group influence the evolutionary outcome of the other's fixation probabilities of strategies within its own group. Analytical analysis and numerical calculations are performed to study the evolutionary dynamics of strategies in typical classes of two-player games (prisoner's dilemma game, snowdrift game, and stag-hunt game). The introduction of the heterogeneity in strategy-update time scales leads to substantial changes in the evolution dynamics of strategies. We provide an approximation formula for the fixation probability of mutant types in finite populations and study the outcome of strategy evolution under the weak selection. We find that although heterogeneity in time scales makes the collective evolutionary dynamics more complicated, the possible long-run evolutionary outcome can be effectively predicted under technical assumptions when knowing the population composition and payoff parameters.

Management practices associated with pain in cattle on western Canadian cow-calf operations: A mixed methods study.

PubMed

Moggy, M A; Pajor, E A; Thurston, W E; Parker, S; Greter, A M; Schwartzkopf-Genswein, K S; Campbell, J R; Windeyer, M C

2017-02-01

The implementation of on-farm pain mitigation strategies is dependent on feasibility and importance to producers. Currently, there is a lack of information regarding adoption of management practices associated with pain in cattle within the Canadian beef industry. The objective of this mixed methods study was to describe pain-associated practices implemented on farm and producer perceptions toward pain mitigation strategies. A questionnaire about calving management and calf processing was delivered to 109 cow-calf producers in western Canada. In addition, 15 respondents were purposively selected based on questionnaire responses to participate in individual semistructured, on-farm interviews. The prevalence of pain mitigation strategies used for dystocia and cesarean section by respondents were 46 and 100%, respectively. The majority of operations reported castrating and dehorning calves before 3 mo of age (95 and 89%, respectively). The majority of operations did not use pain mitigation strategies for castration and dehorning (90 and 85%, respectively). Branding was practiced by 57% of respondents, 4% of which used pain mitigation. Thematic content analysis revealed that producers' perception of pain were influenced by what they referred to as "common sense," relatability to cattle, visual evidence of pain, and age of the animal. Factors that influenced participant rationale for the implementation of pain mitigation practices included access to information and resources, age of the animal, benefit to the operation, cost and logistics, market demands, and personal conscience. Overall, management practices were generally in compliance with published Canadian guidelines. Results of this study may provide direction for future policy making, research, and extension efforts to encourage the adoption of pain mitigation strategies.

The Puerto Rico Component of the National Tsunami Hazard and Mitigation Program Pr-Nthmp

NASA Astrophysics Data System (ADS)

Huerfano Moreno, V. A.; Hincapie-Cardenas, C. M.

2014-12-01

Tsunami hazard assessment, detection, warning, education and outreach efforts are intended to reduce losses to life and property. The Puerto Rico Seismic Network (PRSN) is participating in an effort with local and federal agencies, to developing tsunami hazard risk reduction strategies under the National Tsunami Hazards and Mitigation Program (NTHMP). This grant supports the TsunamiReady program which is the base of the tsunami preparedness and mitigation in PR. The Caribbean region has a documented history of damaging tsunamis that have affected coastal areas. The seismic water waves originating in the prominent fault systems around PR are considered to be a near-field hazard for Puerto Rico and the Virgin islands (PR/VI) because they can reach coastal areas within a few minutes after the earthquake. Sources for local, regional and tele tsunamis have been identified and modeled and tsunami evacuation maps were prepared for PR. These maps were generated in three phases: First, hypothetical tsunami scenarios on the basis of the parameters of potential underwater earthquakes were developed. Secondly, each of these scenarios was simulated. The third step was to determine the worst case scenario (MOM). The run-ups were drawn on GIS referenced maps and aerial photographs. These products are being used by emergency managers to educate the public and develop mitigation strategies. Online maps and related evacuation products are available to the public via the PR-TDST (PR Tsunami Decision Support Tool). Currently all the 44 coastal municipalities were recognized as TsunamiReady by the US NWS. The main goal of the program is to declare Puerto Rico as TsunamiReady, including two cities that are not coastal but could be affected by tsunamis. Based on these evacuation maps, tsunami signs were installed, vulnerability profiles were created, communication systems to receive and disseminate tsunami messages were installed in each TWFP, and tsunami response plans were approved. Also, the existing tsunami protocol and criteria in the PR/VI was updated. This paper describes the PR-NTHMP project, including the real time earthquake and tsunami monitoring as well as the specific protocols used to broadcast tsunami messages. The paper highlights tsunami hazards assessment, detection, warning, education and outreach in Puerto Rico.

Model updating strategy for structures with localised nonlinearities using frequency response measurements

NASA Astrophysics Data System (ADS)

Wang, Xing; Hill, Thomas L.; Neild, Simon A.; Shaw, Alexander D.; Haddad Khodaparast, Hamed; Friswell, Michael I.

2018-02-01

This paper proposes a model updating strategy for localised nonlinear structures. It utilises an initial finite-element (FE) model of the structure and primary harmonic response data taken from low and high amplitude excitations. The underlying linear part of the FE model is first updated using low-amplitude test data with established techniques. Then, using this linear FE model, the nonlinear elements are localised, characterised, and quantified with primary harmonic response data measured under stepped-sine or swept-sine excitations. Finally, the resulting model is validated by comparing the analytical predictions with both the measured responses used in the updating and with additional test data. The proposed strategy is applied to a clamped beam with a nonlinear mechanism and good agreements between the analytical predictions and measured responses are achieved. Discussions on issues of damping estimation and dealing with data from amplitude-varying force input in the updating process are also provided.

2016 Decadal Update of the NASA ESTO Lidar Technologies Investment Strategy

NASA Technical Reports Server (NTRS)

Valinia, Azita; Tratt, David M.; Lotshaw, William T.; Gaab, Kevin M.; Komar, George J.; Rioux, Norman M.; Perez, Mario R.; Smith, Erin C.

2016-01-01

We describe the 2016 update of the NASA Earth Science Technology Office (ESTO) investment strategy in the area of lidar technologies as pertaining to NASAs Earth Science measurement goals in the next decade.

40 CFR 501.21 - Program reporting to EPA.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Section 501.21 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SEWAGE SLUDGE STATE... its inventory of sewage sludge generators and sludge disposal facilities, and provide information on... mitigate the incident(s) of noncompliance. (b) Information to update the inventory of all sewage sludge...

Ambient Air Mitigation Strategies for Reducing Exposures to Mobile Source PM2.5 Emissions

EPA Science Inventory

Presentation discussing ambient air mitigation strategies for near-road exposures. The presentation provides an overview of multiple methods, but focuses on the role roadside features (sound walls, vegetation) may play. This presentation summarizes preoviously published work by...

A SWOT Analysis of the Updated National HIV/AIDS Strategy for the U.S., 2015-2020.

PubMed

Holtgrave, David R; Greenwald, Robert

2016-01-01

In July 2015, President Barack Obama released an updated National HIV/AIDS Strategy (NHAS) for the United States to guide HIV efforts through the year 2020. A federal action plan to accompany the updated NHAS will be released in December 2015. In this editorial, we offer a strengths, weaknesses, opportunities and threats analysis with the aim of increasing discussion of ways to truly fulfill the promise of the updated NHAS and to address barriers that may thwart it from achieving its full potential.

Ontology-Driven Search and Triage: Design of a Web-Based Visual Interface for MEDLINE.

PubMed

Demelo, Jonathan; Parsons, Paul; Sedig, Kamran

2017-02-02

Diverse users need to search health and medical literature to satisfy open-ended goals such as making evidence-based decisions and updating their knowledge. However, doing so is challenging due to at least two major difficulties: (1) articulating information needs using accurate vocabulary and (2) dealing with large document sets returned from searches. Common search interfaces such as PubMed do not provide adequate support for exploratory search tasks. Our objective was to improve support for exploratory search tasks by combining two strategies in the design of an interactive visual interface by (1) using a formal ontology to help users build domain-specific knowledge and vocabulary and (2) providing multi-stage triaging support to help mitigate the information overload problem. We developed a Web-based tool, Ontology-Driven Visual Search and Triage Interface for MEDLINE (OVERT-MED), to test our design ideas. We implemented a custom searchable index of MEDLINE, which comprises approximately 25 million document citations. We chose a popular biomedical ontology, the Human Phenotype Ontology (HPO), to test our solution to the vocabulary problem. We implemented multistage triaging support in OVERT-MED, with the aid of interactive visualization techniques, to help users deal with large document sets returned from searches. Formative evaluation suggests that the design features in OVERT-MED are helpful in addressing the two major difficulties described above. Using a formal ontology seems to help users articulate their information needs with more accurate vocabulary. In addition, multistage triaging combined with interactive visualizations shows promise in mitigating the information overload problem. Our strategies appear to be valuable in addressing the two major problems in exploratory search. Although we tested OVERT-MED with a particular ontology and document collection, we anticipate that our strategies can be transferred successfully to other contexts. ©Jonathan Demelo, Paul Parsons, Kamran Sedig. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 02.02.2017.

Ontology-Driven Search and Triage: Design of a Web-Based Visual Interface for MEDLINE

PubMed Central

2017-01-01

Background Diverse users need to search health and medical literature to satisfy open-ended goals such as making evidence-based decisions and updating their knowledge. However, doing so is challenging due to at least two major difficulties: (1) articulating information needs using accurate vocabulary and (2) dealing with large document sets returned from searches. Common search interfaces such as PubMed do not provide adequate support for exploratory search tasks. Objective Our objective was to improve support for exploratory search tasks by combining two strategies in the design of an interactive visual interface by (1) using a formal ontology to help users build domain-specific knowledge and vocabulary and (2) providing multi-stage triaging support to help mitigate the information overload problem. Methods We developed a Web-based tool, Ontology-Driven Visual Search and Triage Interface for MEDLINE (OVERT-MED), to test our design ideas. We implemented a custom searchable index of MEDLINE, which comprises approximately 25 million document citations. We chose a popular biomedical ontology, the Human Phenotype Ontology (HPO), to test our solution to the vocabulary problem. We implemented multistage triaging support in OVERT-MED, with the aid of interactive visualization techniques, to help users deal with large document sets returned from searches. Results Formative evaluation suggests that the design features in OVERT-MED are helpful in addressing the two major difficulties described above. Using a formal ontology seems to help users articulate their information needs with more accurate vocabulary. In addition, multistage triaging combined with interactive visualizations shows promise in mitigating the information overload problem. Conclusions Our strategies appear to be valuable in addressing the two major problems in exploratory search. Although we tested OVERT-MED with a particular ontology and document collection, we anticipate that our strategies can be transferred successfully to other contexts. PMID:28153818

78 FR 16875 - Request of the U.S. Intellectual Property Enforcement Coordinator for Public Comments...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-19

..._strategy_on_mitigating_the_theft_of_u.s._trade_secrets.pdf http:/www.whitehouse.gov/sites/default/files/omb/ IPEC/admin_strategy_on_mitigating_the_theft_of_u.s._trade_ secrets.pdf. A related OMB blog post is...

Value of travel-time reliability, part II : a study of tradeoffs between travel reliability, congestion-mitigation strategies and emissions.

DOT National Transportation Integrated Search

2012-09-01

Capacity, demand, and vehicle based emissions reduction strategies are compared for several pollutants employing aggregate US : congestion and vehicle fleet condition data. We find that congestion mitigation does not inevitably lead to reduced emissi...

Investigation of Coating and Corrosion Mitigation Strategies in Magnesium/Mixed Metal Assemblies

NASA Astrophysics Data System (ADS)

Forsmark, Joy H.; McCune, Robert C.; Giles, Terry; Audette, Michelle; Snowden, Jasmine; Stalker, Jeff; Morey, Matthew; O'Keefe, Matt; Castano, Carlos

The US Automotive Materials Partnership through the Magnesium-Intensive Front End Development Project (MFERD) is currently investigating a number of joining, coating and corrosion mitigation strategies to incorporate magnesium components into the automotive body-in-white with the ultimate goal of decreasing vehicle curb weight, thus improving fuel economy. Because Mg is anodic to all other structural metals, this is a key hurdle to Mg component implementation in vehicles. This paper will discuss the results of a study to examine the effectiveness of different corrosion mitigation strategies in joined plate assemblies and provide some insight into the systems challenges of incorporation of Mg parts into a vehicle. Details of a statistically-designed experiment developed to explore the interaction of several materials of construction (magnesium, steel and aluminum), pretreatment and topcoatings, joining methods and standardized test protocols including SAE J-2334 and ASTM B-117 are discussed. A number of avenues have emerged from this study as potential strategies for corrosion mitigation.

Carbon dioxide capture strategies from flue gas using microalgae: a review.

PubMed

Thomas, Daniya M; Mechery, Jerry; Paulose, Sylas V

2016-09-01

Global warming and pollution are the twin crises experienced globally. Biological offset of these crises are gaining importance because of its zero waste production and the ability of the organisms to thrive under extreme or polluted condition. In this context, this review highlights the recent developments in carbon dioxide (CO2) capture from flue gas using microalgae and finding the best microalgal remediation strategy through contrast and comparison of different strategies. Different flue gas microalgal remediation strategies discussed are as follows: (i) Flue gas to CO2 gas segregation using adsorbents for microalgal mitigation, (ii) CO2 separation from flue gas using absorbents and later regeneration for microalgal mitigation, (iii) Flue gas to liquid conversion for direct microalgal mitigation, and (iv) direct flue gas mitigation using microalgae. This work also studies the economic feasibility of microalgal production. The study discloses that the direct convening of flue gas with high carbon dioxide content, into microalgal system is cost-effective.

78 FR 50435 - Agency Information Collection Activities; Proposed Collection; Comment Request: FEMA Mitigation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-19

... Mitigation Success Story Database AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY... (GPRA) (Pub. L. 103.62 Section 2) FEMA has established the FEMA Mitigation Best Practices success story... stories incorporate mitigation strategies that have been successfully implemented and provide real- world...

U.S. States and Territories National Tsunami Hazard Assessment: Historical record and sources for waves – Update

USGS Publications Warehouse

Dunbar, Paula K.; Weaver, Craig S.

2015-01-01

The first U.S. Tsunami Hazard Assessment (Dunbar and Weaver, 2008) was prepared at the request of the National Tsunami Hazard Mitigation Program (NTHMP). The NTHMP is a partnership formed between federal and state agencies to reduce the impact of tsunamis through hazard assessment, warning guidance, and mitigation. The assessment was conducted in response to a 2005 joint report by the Sub-Committee on Disaster Reduction and the U.S. Group on Earth Observations entitled Tsunami Risk Reduction for the United States: A Framework for Action. The first specific action called for in the Framework was to “develop standardized and coordinated tsunami hazard and risk assessments for all coastal regions of the United States and its territories.” Since the first assessment, there have been a number of very significant tsunamis, including the 2009 Samoa, 2010 Chile, and 2011 Japan tsunamis. As a result, the NTHMP requested an update of the U.S. tsunami hazard assessment.

New Developments in FPGA: SEUs and Fail-Safe Strategies from the NASA Goddard Perspective

NASA Technical Reports Server (NTRS)

Berg, Melanie D.; Label, Kenneth A.; Pellish, Jonathan

2016-01-01

It has been shown that, when exposed to radiation environments, each Field Programmable Gate Array (FPGA) device has unique error signatures. Subsequently, fail-safe and mitigation strategies will differ per FPGA type. In this session several design approaches for safe systems will be presented. It will also explore the benefits and limitations of several mitigation techniques. The intention of the presentation is to provide information regarding FPGA types, their susceptibilities, and proven fail-safe strategies; so that users can select appropriate mitigation and perform the required trade for system insertion. The presentation will describe three types of FPGA devices and their susceptibilities in radiation environments.

New Developments in FPGA: SEUs and Fail-Safe Strategies from the NASA Goddard Perspective

NASA Technical Reports Server (NTRS)

Berg, Melanie D.; LaBel, Kenneth; Pellish, Jonathan

2015-01-01

It has been shown that, when exposed to radiation environments, each Field Programmable Gate Array (FPGA) device has unique error signatures. Subsequently, fail-safe and mitigation strategies will differ per FPGA type. In this session several design approaches for safe systems will be presented. It will also explore the benefits and limitations of several mitigation techniques. The intention of the presentation is to provide information regarding FPGA types, their susceptibilities, and proven fail-safe strategies; so that users can select appropriate mitigation and perform the required trade for system insertion. The presentation will describe three types of FPGA devices and their susceptibilities in radiation environments.

Radio Frequency Interference Mitigation

NASA Astrophysics Data System (ADS)

An, T.; Chen, X.; Mohan, P.; Lao, B. Q.

2017-09-01

The observational facilities of radio astronomy keep constant upgrades and developments to achieve better capabilities including increasing the time of the data recording and frequency resolutions, and increasing the receiving and recording bandwidth. However in contrast, only a limited spectrum resource has been allocated to radio astronomy by the International Telecommunication Union, resulting in that the radio observational instrumentations are inevitably exposed to undesirable radio frequency interference (RFI) signals which originate mainly from the terrestrial human activity and are becoming stronger with time. RFIs degrade the quality of data and even lead to invalid data. The impact of RFIs on scientific outcome becomes more and more serious. In this article, the requirement for RFI mitigation is motivated, and the RFI characteristics, mitigation techniques, and strategies are reviewed. The mitigation strategies adopted at some representative observatories, telescopes, and arrays are also introduced. The advantages and shortcomings of the four classes of RFI mitigation strategies are discussed and presented, applicable at the connected causal stages: preventive, pre-detection, pre-correlation, and post-correlation. The proper identification and flagging of RFI is the key to the reduction of data loss and improvement in data quality, and is also the ultimate goal of developing RFI mitigation technique. This can be achieved through a strategy involving a combination of the discussed techniques in stages. The recent advances in the high speed digital signal processing and high performance computing allow for performing RFI excision of the large data volumes generated from large telescopes or arrays in both real time and offline modes, aiding the proposed strategy.

Experiments on individual strategy updating in iterated snowdrift game under random rematching.

PubMed

Qi, Hang; Ma, Shoufeng; Jia, Ning; Wang, Guangchao

2015-03-07

How do people actually play the iterated snowdrift games, particularly under random rematching protocol is far from well explored. Two sets of laboratory experiments on snowdrift game were conducted to investigate human strategy updating rules. Four groups of subjects were modeled by experience-weighted attraction learning theory at individual-level. Three out of the four groups (75%) passed model validation. Substantial heterogeneity is observed among the players who update their strategies in four typical types, whereas rare people behave like belief-based learners even under fixed pairing. Most subjects (63.9%) adopt the reinforcement learning (or alike) rules; but, interestingly, the performance of averaged reinforcement learners suffered. It is observed that two factors seem to benefit players in competition, i.e., the sensitivity to their recent experiences and the overall consideration of forgone payoffs. Moreover, subjects with changing opponents tend to learn faster based on their own recent experience, and display more diverse strategy updating rules than they do with fixed opponent. These findings suggest that most of subjects do apply reinforcement learning alike updating rules even under random rematching, although these rules may not improve their performance. The findings help evolutionary biology researchers to understand sophisticated human behavioral strategies in social dilemmas. Copyright © 2015 Elsevier Ltd. All rights reserved.

Status and Performance Updates for the Cosmic Origins Spectrograph

NASA Astrophysics Data System (ADS)

Snyder, Elaine M.; De Rosa, Gisella; Fischer, William J.; Fix, Mees; Fox, Andrew; Indriolo, Nick; James, Bethan; Oliveira, Cristina M.; Penton, Steven V.; Plesha, Rachel; Rafelski, Marc; Roman-Duval, Julia; Sahnow, David J.; Sankrit, Ravi; Taylor, Joanna M.; White, James

2018-01-01

The Hubble Space Telescope's Cosmic Origins Spectrograph (COS) moved the spectra on the FUV detector from Lifetime Position 3 (LP3) to a new pristine location, LP4, in October 2017. The spectra were shifted in the cross-dispersion direction by -2.5" (roughly -31 pixels) from LP3, or -5" (roughly -62 pixels) from the original LP1. This move mitigates the adverse effects of gain sag on the spectral quality and accuracy of COS FUV observations. Here, we present updates regarding the calibration of FUV data at LP4, including the flat fields, flux calibrations, and spectral resolution. We also present updates on the time-dependent sensitivities and dark rates of both the NUV and FUV detectors.

Ranking current and prospective NO2 pollution mitigation strategies: An environmental and economic modelling investigation in Oxford Street, London.

PubMed

Jeanjean, A P R; Gallagher, J; Monks, P S; Leigh, R J

2017-06-01

Air pollution continues to be a problem in the urban environment. A range of different pollutant mitigation strategies that promote dispersion and deposition exist, but there is little evidence with respect to their comparative performance from both an environmental and economic perspective. This paper focuses on examining different NO 2 mitigation strategies such as trees, buildings facades coated with photocatalytic paint and solid barriers in Oxford Street in London. The case study findings will support ranking the environmental and economic impacts of these different strategies to improve personal exposure conditions on the footpath and on the road in a real urban street canyon. CFD simulations of airflow and NO 2 dispersion in Oxford Street in London were undertaken using the OpenFOAM software platform with the k-ε model, taking into account local prevailing wind conditions. Trees are shown to be the most cost-effective strategy, with a small reduction in NO 2 concentrations of up to 0.7% on the road. However, solid barriers with and without the application of photocatalytic paint and an innovative material (20 times more expensive than trees) can improve air quality on the footpaths more substantially, up to 7.4%, yet this has a significant detrimental impact on NO 2 concentrations (≤23.8%) on the road. Photocatalytic paint on building surfaces presented a minimal environmental reductions (1.2%) and economic (>100 times more expensive than trees) mitigation strategy. The findings recognised the differences between footpath and road concentrations occurred and that a focused examination of three pollution hotspots can provide more cost effective pollution mitigation. This study considers how a number of pollutant mitigation measures can be applied in a single street canyon and demonstrates the strengths and weaknesses of these strategies from economic and environmental perspectives. Further research is required to extrapolate the findings presented here to different street geometries. Copyright © 2017. Published by Elsevier Ltd.

Shift changes, updates, and the on-call architecture in space shuttle mission control.

PubMed

Patterson, E S; Woods, D D

2001-01-01

In domains such as nuclear power, industrial process control, and space shuttle mission control, there is increased interest in reducing personnel during nominal operations. An essential element in maintaining safe operations in high risk environments with this 'on-call' organizational architecture is to understand how to bring called-in practitioners up to speed quickly during escalating situations. Targeted field observations were conducted to investigate what it means to update a supervisory controller on the status of a continuous, anomaly-driven process in a complex, distributed environment. Sixteen shift changes, or handovers, at the NASA Johnson Space Center were observed during the STS-76 Space Shuttle mission. The findings from this observational study highlight the importance of prior knowledge in the updates and demonstrate how missing updates can leave flight controllers vulnerable to being unprepared. Implications for mitigating risk in the transition to 'on-call' architectures are discussed.

Shift changes, updates, and the on-call architecture in space shuttle mission control

NASA Technical Reports Server (NTRS)

Patterson, E. S.; Woods, D. D.

2001-01-01

In domains such as nuclear power, industrial process control, and space shuttle mission control, there is increased interest in reducing personnel during nominal operations. An essential element in maintaining safe operations in high risk environments with this 'on-call' organizational architecture is to understand how to bring called-in practitioners up to speed quickly during escalating situations. Targeted field observations were conducted to investigate what it means to update a supervisory controller on the status of a continuous, anomaly-driven process in a complex, distributed environment. Sixteen shift changes, or handovers, at the NASA Johnson Space Center were observed during the STS-76 Space Shuttle mission. The findings from this observational study highlight the importance of prior knowledge in the updates and demonstrate how missing updates can leave flight controllers vulnerable to being unprepared. Implications for mitigating risk in the transition to 'on-call' architectures are discussed.

Earthquake and Tsunami Disaster Mitigation in The Marmara Region and Disaster Education in Turkey Part2 Yoshiyuki KANEDA Nagoya University Japan Agency for Marine-Earth Science and Technology (JAMSTEC) Haluk OZENER Boğaziçi University, Earthquake Researches Institute (KOERI) and Members of SATREPS Japan-Turkey project

NASA Astrophysics Data System (ADS)

Kaneda, Y.; Ozener, H.

2015-12-01

The 1999 Izumit Earthquake as the destructive earthquake occurred near the Marmara Sea. The Marmara Sea should be focused on because of a seismic gap in the North Anatolian fault. Istanbul is located around the Marmara Sea, so, if next earthquake will occur near Istanbul, fatal damages will be generated. The Japan and Turkey can share our own experiences during past damaging earthquakes and we can prepare for future large earthquakes in cooperation with each other. In earthquakes in Tokyo area and Istanbul area as the destructive earthquakes near high population cities, there are common disaster researches and measures. For disaster mitigation, we are progressing multidisciplinary researches. Our goals of this SATREPS project are as follows, To develop disaster mitigation policy and strategies based on multidisciplinary research activities. To provide decision makers with newly found knowledge for its implementation to the current regulations. To organize disaster education programs in order to increase disaster awareness in Turkey. To contribute the evaluation of active fault studies in Japan. This project is composed of four research groups. The first group is Marmara Earthquake Source region observationally research group. This group has 4 sub-themes such as Seismicity, Geodesy, Electromagnetics and Trench analyses. The second group focuses on scenario researches of earthquake occurrence along the North Anatolia fault and precise tsunami simulation in the Marmara region. Aims of the third group are improvements and constructions of seismic characterizations and damage predictions based on observation researches and precise simulations. The fourth group is promoting disaster educations using research result visuals. In this SATREPS project, we will integrate these research results for disaster mitigation in Marmara region and .disaster education in Turkey. We will have a presentation of the updated results of this SATREPS project.

Detector Damage at X-Ray Free-Electron Laser Sources

NASA Astrophysics Data System (ADS)

Blaj, G.; Carini, G.; Carron, S.; Haller, G.; Hart, P.; Hasi, J.; Herrmann, S.; Kenney, C.; Segal, J.; Stan, C. A.; Tomada, A.

2016-06-01

Free-electron lasers (FELs) opened a new window on imaging the motion of atoms and molecules. At SLAC, FEL experiments are performed at LCLS using 120 Hz pulses with 1012 to 1013 photons in 10 fs (billions of times brighter than at the most powerful synchrotrons). Concurrently, users and staff operate under high pressure due to flexible and often rapidly changing setups and low tolerance for system malfunction. This extreme detection environment raises unique challenges, from obvious to surprising, and leads to treating detectors as consumables. We discuss in detail the detector damage mechanisms observed in 7 years of operation at LCLS, together with the corresponding damage mitigation strategies and their effectiveness. Main types of damage mechanisms already identified include: (1) x-ray radiation damage (from “catastrophic” to “classical”), (2) direct and indirect damage caused by optical lasers, (3) sample induced damage, (4) vacuum related damage, (5) high-pressure environment. In total, 19 damage mechanisms have been identified. We also present general strategies for reducing damage risk or minimizing the impact of detector damage on the science program. These include availability of replacement parts and skilled operators and also careful planning, incident investigation resulting in updated designs, procedures and operator training.

Current Status of Rift Valley Fever Vaccine Development

PubMed Central

Faburay, Bonto; LaBeaud, Angelle Desiree; McVey, D. Scott; Wilson, William C.; Richt, Juergen A.

2017-01-01

Rift Valley Fever (RVF) is a mosquito-borne zoonotic disease that presents a substantial threat to human and public health. It is caused by Rift Valley fever phlebovirus (RVFV), which belongs to the genus Phlebovirus and the family Phenuiviridae within the order Bunyavirales. The wide distribution of competent vectors in non-endemic areas coupled with global climate change poses a significant threat of the transboundary spread of RVFV. In the last decade, an improved understanding of the molecular biology of RVFV has facilitated significant progress in the development of novel vaccines, including DIVA (differentiating infected from vaccinated animals) vaccines. Despite these advances, there is no fully licensed vaccine for veterinary or human use available in non-endemic countries, whereas in endemic countries, there is no clear policy or practice of routine/strategic livestock vaccinations as a preventive or mitigating strategy against potential RVF disease outbreaks. The purpose of this review was to provide an update on the status of RVF vaccine development and provide perspectives on the best strategies for disease control. Herein, we argue that the routine or strategic vaccination of livestock could be the best control approach for preventing the outbreak and spread of future disease. PMID:28925970

National Drug Control Strategy. Update

ERIC Educational Resources Information Center

Office of National Drug Control Policy, 2005

2005-01-01

The first National Drug Control Strategy set ambitious two and five-year performance based goals: (1) to lower the rate of drug use by 10 percent over 2 years among both youth and adults; and (2) to lower the rate by 25 percent over 5 years. The chapters in this updated version are keyed to the strategies three priorities: (1) Stopping Use Before…

Keeping it wild 2: An updated interagency strategy to monitor trends in wilderness character across the National Wilderness Preservation System

Treesearch

Peter Landres; Chris Barns; Steve Boutcher; Tim Devine; Peter Dratch; Adrienne Lindholm; Linda Merigliano; Nancy Roeper; Emily Simpson

2015-01-01

Keeping It Wild 2 is an interagency strategy to monitor trends in selected attributes of wilderness character based on lessons learned from 15 years of developing and implementing wilderness character monitoring across the National Wilderness Preservation System. This document updates and replaces Keeping It Wild: An Interagency Strategy for Monitoring Wilderness...

Strategies to mitigate peanut allergy: production, processing, utilization, and immunotherapy considerations

USDA-ARS?s Scientific Manuscript database

Peanut (Arachis hypogaea L.) is an important crop grown worldwide for food and edible oil. The surge of peanut allergy in the past 25 years has profoundly impacted both affected individuals and the peanut and related food industries. In response, several strategies to mitigate peanut allergy have em...

Extending the life of asphalt pavements : part II Implementation plan: mitigation strategies & demonstration/pilot projects products P1 and P3.

DOT National Transportation Integrated Search

2011-01-01

This report presents the mitigation strategies and demonstration/pilot projects that are recommended to enhance performance and reduce the occurrence of pavements exhibiting accelerated aging or deterioration. The report is grouped into two parts, fo...

76 FR 31379 - Notice of Issuance of Bulletin 2011-01, Mitigating Strategies

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

..., Office of Nuclear Reactor Regulation, U.S. Nuclear Regulatory Commission. Telephone: 301-415-2963; e-mail... NUCLEAR REGULATORY COMMISSION [NRC-2011-0120] Notice of Issuance of Bulletin 2011-01, Mitigating Strategies AGENCY: U.S. Nuclear Regulatory Commission. ACTION: Notice of Issuance. SUMMARY: The U.S. Nuclear...

The Impacts of Climate Change Mitigation Strategies on Animal Welfare.

PubMed

Shields, Sara; Orme-Evans, Geoffrey

2015-05-21

The objective of this review is to point out that the global dialog on reducing greenhouse gas emissions in animal agriculture has, thus far, not adequately considered animal welfare in proposed climate change mitigation strategies. Many suggested approaches for reducing emissions, most of which could generally be described as calls for the intensification of production, can have substantial effects on the animals. Given the growing world-wide awareness and concern for animal welfare, many of these approaches are not socially sustainable. This review identifies the main emission abatement strategies in the climate change literature that would negatively affect animal welfare and details the associated problems. Alternative strategies are also identified as possible solutions for animal welfare and climate change, and it is suggested that more attention be focused on these types of options when allocating resources, researching mitigation strategies, and making policy decisions on reducing emissions from animal agriculture.

77 FR 35866 - Approval and Promulgation of Implementation Plans; Revisions to the Georgia State Implementation...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... (GA DNR), on November 16, 2010. This revision consists of transportation conformity criteria and procedures related to interagency consultation and enforceability of certain transportation-related control measures and mitigation measures. The intended effect is to update the transportation conformity criteria...

Comparison of Strategies for Climate Change Adaptation of Water Supply and Flood Control Reservoirs

NASA Astrophysics Data System (ADS)

Ng, T. L.; Yang, P.; Bhushan, R.

2016-12-01

With climate change, streamflows are expected to become more fluctuating, with more frequent and intense floods and droughts. This complicates reservoir operation, which is highly sensitive to inflow variability. We make a comparative evaluation of three strategies for adapting reservoirs to climate-induced shifts in streamflow patterns. Specifically, we examine the effectiveness of (i) expanding the capacities of reservoirs by way of new off-stream reservoirs, (ii) introducing wastewater reclamation to augment supplies, and (iii) improving real-time streamflow forecasts for more optimal decision-making. The first two are hard strategies involving major infrastructure modifications, while the third a soft strategy entailing adjusting the system operation. A comprehensive side-by-side comparison of the three strategies is as yet lacking in the literature despite the many past studies investigating the strategies individually. To this end, we developed an adaptive forward-looking linear program that solves to yield the optimal decisions for the current time as a function of an ensemble forecast of future streamflows. Solving the model repeatedly on a rolling basis with regular updating of the streamflow forecast simulates the system behavior over the entire operating horizon. Results are generated for two hypothetical water supply and flood control reservoirs of differing inflows and demands. Preliminary findings suggest that of the three strategies, improving streamflow forecasts to be most effective in mitigating the effects of climate change. We also found that, in average terms, both additional reservoir capacity and wastewater reclamation have potential to reduce water shortage and downstream flooding. However, in the worst case, the potential of the former to reduce water shortage is limited, and similarly so the potential of the latter to reduce downstream flooding.

77 FR 67040 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-08

... Proposal Regarding Quote Mitigation November 2, 2012. Pursuant to Section 19(b)(1) under the Securities... (Quote Mitigation) and refine the current quote mitigation strategy for its options trading facility, BOX Market LLC (``BOX'') by replacing the current quote mitigation rule with a ``holdback timer'' mechanism...

Mitigating hyperventilation during cardiopulmonary resuscitation.

PubMed

Nikolla, Dhimitri; Lewandowski, Tyler; Carlson, Jestin

2016-03-01

Although multiple airway management and ventilation strategies have been proposed during cardiac arrest, the ideal strategy is unknown. Current strategies call for advanced airways, such as endotracheal intubation and supraglottic airways. These may facilitate hyperventilation which is known to adversely affect cardiopulmonary physiology. We provide a summary of conceptual models linking hyperventilation to patient outcomes and identify methods for mitigating hyperventilation during cardiac arrest. Copyright © 2015 Elsevier Inc. All rights reserved.

Economic optimization of a global strategy to address the pandemic threat.

PubMed

Pike, Jamison; Bogich, Tiffany; Elwood, Sarah; Finnoff, David C; Daszak, Peter

2014-12-30

Emerging pandemics threaten global health and economies and are increasing in frequency. Globally coordinated strategies to combat pandemics, similar to current strategies that address climate change, are largely adaptive, in that they attempt to reduce the impact of a pathogen after it has emerged. However, like climate change, mitigation strategies have been developed that include programs to reduce the underlying drivers of pandemics, particularly animal-to-human disease transmission. Here, we use real options economic modeling of current globally coordinated adaptation strategies for pandemic prevention. We show that they would be optimally implemented within 27 y to reduce the annual rise of emerging infectious disease events by 50% at an estimated one-time cost of approximately $343.7 billion. We then analyze World Bank data on multilateral "One Health" pandemic mitigation programs. We find that, because most pandemics have animal origins, mitigation is a more cost-effective policy than business-as-usual adaptation programs, saving between $344.0.7 billion and $360.3 billion over the next 100 y if implemented today. We conclude that globally coordinated pandemic prevention policies need to be enacted urgently to be optimally effective and that strategies to mitigate pandemics by reducing the impact of their underlying drivers are likely to be more effective than business as usual.

Economic optimization of a global strategy to address the pandemic threat

PubMed Central

Pike, Jamison; Bogich, Tiffany; Elwood, Sarah; Finnoff, David C.; Daszak, Peter

2014-01-01

Emerging pandemics threaten global health and economies and are increasing in frequency. Globally coordinated strategies to combat pandemics, similar to current strategies that address climate change, are largely adaptive, in that they attempt to reduce the impact of a pathogen after it has emerged. However, like climate change, mitigation strategies have been developed that include programs to reduce the underlying drivers of pandemics, particularly animal-to-human disease transmission. Here, we use real options economic modeling of current globally coordinated adaptation strategies for pandemic prevention. We show that they would be optimally implemented within 27 y to reduce the annual rise of emerging infectious disease events by 50% at an estimated one-time cost of approximately $343.7 billion. We then analyze World Bank data on multilateral “One Health” pandemic mitigation programs. We find that, because most pandemics have animal origins, mitigation is a more cost-effective policy than business-as-usual adaptation programs, saving between $344.0.7 billion and $360.3 billion over the next 100 y if implemented today. We conclude that globally coordinated pandemic prevention policies need to be enacted urgently to be optimally effective and that strategies to mitigate pandemics by reducing the impact of their underlying drivers are likely to be more effective than business as usual. PMID:25512538

LightForce Photon-Pressure Collision Avoidance: Updated Efficiency Analysis Utilizing a Highly Parallel Simulation Approach

NASA Technical Reports Server (NTRS)

Stupl, Jan; Faber, Nicolas; Foster, Cyrus; Yang, Fan Yang; Nelson, Bron; Aziz, Jonathan; Nuttall, Andrew; Henze, Chris; Levit, Creon

2014-01-01

This paper provides an updated efficiency analysis of the LightForce space debris collision avoidance scheme. LightForce aims to prevent collisions on warning by utilizing photon pressure from ground based, commercial off the shelf lasers. Past research has shown that a few ground-based systems consisting of 10 kilowatt class lasers directed by 1.5 meter telescopes with adaptive optics could lower the expected number of collisions in Low Earth Orbit (LEO) by an order of magnitude. Our simulation approach utilizes the entire Two Line Element (TLE) catalogue in LEO for a given day as initial input. Least-squares fitting of a TLE time series is used for an improved orbit estimate. We then calculate the probability of collision for all LEO objects in the catalogue for a time step of the simulation. The conjunctions that exceed a threshold probability of collision are then engaged by a simulated network of laser ground stations. After those engagements, the perturbed orbits are used to re-assess the probability of collision and evaluate the efficiency of the system. This paper describes new simulations with three updated aspects: 1) By utilizing a highly parallel simulation approach employing hundreds of processors, we have extended our analysis to a much broader dataset. The simulation time is extended to one year. 2) We analyze not only the efficiency of LightForce on conjunctions that naturally occur, but also take into account conjunctions caused by orbit perturbations due to LightForce engagements. 3) We use a new simulation approach that is regularly updating the LightForce engagement strategy, as it would be during actual operations. In this paper we present our simulation approach to parallelize the efficiency analysis, its computational performance and the resulting expected efficiency of the LightForce collision avoidance system. Results indicate that utilizing a network of four LightForce stations with 20 kilowatt lasers, 85% of all conjunctions with a probability of collision Pc > 10 (sup -6) can be mitigated.

An Optimal Mitigation Strategy Against the Asteroid Impact Threat with Short Warning Time

NASA Technical Reports Server (NTRS)

Wie, Bong; Barbee, Brent W.

2015-01-01

This paper presents the results of a NASA Innovative Advanced Concept (NIAC) Phase 2 study entitled "An Innovative Solution to NASA's Near-Earth Object (NEO) Impact Threat Mitigation Grand Challenge and Flight Validation Mission Architecture Development." This NIAC Phase 2 study was conducted at the Asteroid Deflection Research Center (ADRC) of Iowa State University in 2012-2014. The study objective was to develop an innovative yet practically implementable mitigation strategy for the most probable impact threat of an asteroid or comet with short warning time (less than 5 years). The mitigation strategy described in this paper is intended to optimally reduce the severity and catastrophic damage of the NEO impact event, especially when we don't have sufficient warning times for non-disruptive deflection of a hazardous NEO. This paper provides an executive summary of the NIAC Phase 2 study results.

Mitigation of methane emissions in cities: How new measurements and partnerships can contribute to emissions reduction strategies

NASA Astrophysics Data System (ADS)

Hopkins, Francesca M.; Ehleringer, James R.; Bush, Susan E.; Duren, Riley M.; Miller, Charles E.; Lai, Chun-Ta; Hsu, Ying-Kuang; Carranza, Valerie; Randerson, James T.

2016-09-01

Cities generate 70% of anthropogenic greenhouse gas emissions, a fraction that is growing with global urbanization. While cities play an important role in climate change mitigation, there has been little focus on reducing urban methane (CH4) emissions. Here, we develop a conceptual framework for CH4 mitigation in cities by describing emission processes, the role of measurements, and a need for new institutional partnerships. Urban CH4 emissions are likely to grow with expanding use of natural gas and organic waste disposal systems in growing population centers; however, we currently lack the ability to quantify this increase. We also lack systematic knowledge of the relative contribution of these distinct source sectors on emissions. We present new observations from four North American cities to demonstrate that CH4 emissions vary in magnitude and sector from city to city and hence require different mitigation strategies. Detections of fugitive emissions from these systems suggest that current mitigation approaches are absent or ineffective. These findings illustrate that tackling urban CH4 emissions will require research efforts to identify mitigation targets, develop and implement new mitigation strategies, and monitor atmospheric CH4 levels to ensure the success of mitigation efforts. This research will require a variety of techniques to achieve these objectives and should be deployed in cities globally. We suggest that metropolitan scale partnerships may effectively coordinate systematic measurements and actions focused on emission reduction goals.

Mitigating the surface urban heat island: Mechanism study and sensitivity analysis

NASA Astrophysics Data System (ADS)

Meng, Chunlei

2017-08-01

In a surface urban heat island (SUHI), the urban land surface temperature (LST) is usually higher than the temperature of the surrounding rural areas due to human activities and surface characteristics. Because a SUHI has many adverse impacts on urban environment and human health, SUHI mitigation strategies are very important. This paper investigates the mechanism of a SUHI based on the basic physical laws that control the formation of a SUHI; five mitigation strategies are proposed, namely: sprinkling and watering; paving a pervious surface; reducing the anthropogenic heat (AH) release; using a "white roof"; increasing the fractional vegetation cover or leaf area index (LAI). To quantify the effect of these mitigation strategies, 26 sets of experiments are designed and implemented by running the integrated urban land model (IUM). The results of the sensitivity analysis indicate that sprinkling and watering is an effective measure for mitigating a SUHI for an entire day. Decreasing the AH release is also useful for both night- and daytime SUHI mitigation; however, the cooling extent is proportional to the diurnal cycle of AH. Increasing the albedo can reduce the LST in the daytime, especially when the solar radiation is significant; the cooling extent is approximately proportional to the diurnal cycle of the net radiation. Increasing the pervious surface percentage can mitigate the SUHI especially in the daytime. Increasing the fractional vegetation cover can mitigate the SUHI in the daytime but may aggravate the SUHI at night.

Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. II - Regional Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cochran, Jaquelin M.; Palchak, Joseph D; McBennett, Brendan

The higher-spatial-resolution model of 'Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. II - Regional Study' (the Regional Study), which better represents the impact of congestion on least-cost scheduling and dispatch, provides a deeper understanding of the relationship among renewable energy (RE) location, transmission, and system flexibility with regard to RE integration, compared to 'Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. I - National Study.' The Regional Study validates the relative value of mitigation strategies demonstrated in the National Study - namely, coordinatedmore » operations among states reduce production costs, and reducing coal minimum generation levels reduces RE curtailment. Significantly, the Regional Study also highlights a potential barrier to realizing the value of these mitigation strategies: when locations of RE development are planned independently of state-level transmission, intrastate congestion can result in undesirable levels of RE curtailment. Therefore a key objective of this study is to illustrate to state-level power system planners and operators, in particular, how a higher-resolution model, inclusive of intrastate granularity, can be used as a planning tool for two primary purposes: -To better anticipate, understand, and mitigate system constraints that could affect RE integration; and - To provide a modeling framework that can be used as part of future transmission studies and planning efforts. The Regional Study is not intended to predict precisely how RE will affect state-level operations. There is considerable uncertainty regarding the locations of the RE development, as well as how contract terms can affect access to the inherent physical flexibility of the system. But the scenarios analyzed identify the types of issues that can arise under various RE and transmission expansion pathways. The model developed for this study provides a rigorous framework for future work and can be updated with the characteristics of new capacity as more information on the future power system is known.« less

Greening the Grid: Integrating 175 Gigawatts of Renewable Energy into India's Electric Grid - A Detailed Look at the Southern Region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cochran, Jaquelin M

The higher-spatial-resolution model of 'Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. II - Regional Study' (the Regional Study), which better represents the impact of congestion on least-cost scheduling and dispatch, provides a deeper understanding of the relationship among renewable energy (RE) location, transmission, and system flexibility with regard to RE integration, compared to 'Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. I - National Study.' The Regional Study validates the relative value of mitigation strategies demonstrated in the National Study - namely, coordinatedmore » operations among states reduce production costs, and reducing coal minimum generation levels reduces RE curtailment. Significantly, the Regional Study also highlights a potential barrier to realizing the value of these mitigation strategies: when locations of RE development are planned independently of state-level transmission, intrastate congestion can result in undesirable levels of RE curtailment. Therefore a key objective of this study is to illustrate to state-level power system planners and operators, in particular, how a higher-resolution model, inclusive of intrastate granularity, can be used as a planning tool for two primary purposes: to better anticipate, understand, and mitigate system constraints that could affect RE integration; and to provide a modeling framework that can be used as part of future transmission studies and planning efforts. The Regional Study is not intended to predict precisely how RE will affect state-level operations. There is considerable uncertainty regarding the locations of the RE development, as well as how contract terms can affect access to the inherent physical flexibility of the system. But the scenarios analyzed identify the types of issues that can arise under various RE and transmission expansion pathways. The model developed for this study provides a rigorous framework for future work and can be updated with the characteristics of new capacity as more information on the future power system is known.« less

Greening the Grid: Integrating 175 Gigawatts of Renewable Energy into India's Electric Grid - A Detailed Look at the Western Region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cochran, Jaquelin

The higher-spatial-resolution model of 'Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. II - Regional Study' (the Regional Study), which better represents the impact of congestion on least-cost scheduling and dispatch, provides a deeper understanding of the relationship among renewable energy (RE) location, transmission, and system flexibility with regard to RE integration, compared to 'Greening the Grid: Pathways to Integrate 175 Gigawatts of Renewable Energy into India's Electric Grid, Vol. I - National Study.' The Regional Study validates the relative value of mitigation strategies demonstrated in the National Study - namely, coordinatedmore » operations among states reduce production costs, and reducing coal minimum generation levels reduces RE curtailment. Significantly, the Regional Study also highlights a potential barrier to realizing the value of these mitigation strategies: when locations of RE development are planned independently of state-level transmission, intrastate congestion can result in undesirable levels of RE curtailment. Therefore a key objective of this study is to illustrate to state-level power system planners and operators, in particular, how a higher-resolution model, inclusive of intrastate granularity, can be used as a planning tool for two primary purposes: -To better anticipate, understand, and mitigate system constraints that could affect RE integration; and - To provide a modeling framework that can be used as part of future transmission studies and planning efforts. The Regional Study is not intended to predict precisely how RE will affect state-level operations. There is considerable uncertainty regarding the locations of the RE development, as well as how contract terms can affect access to the inherent physical flexibility of the system. But the scenarios analyzed identify the types of issues that can arise under various RE and transmission expansion pathways. The model developed for this study provides a rigorous framework for future work and can be updated with the characteristics of new capacity as more information on the future power system is known.« less

The Puerto Rico Component of the National Tsunami Hazard and Mitigation Program (PR-NTHMP)

NASA Astrophysics Data System (ADS)

Vanacore, E. A.; Huerfano Moreno, V. A.; Lopez, A. M.

2015-12-01

The Caribbean region has a documented history of damaging tsunamis that have affected coastal areas. Of particular interest is the Puerto Rico - Virgin Islands (PRVI) region, where the proximity of the coast to prominent tectonic faults would result in near-field tsunamis. Tsunami hazard assessment, detection capabilities, warning, education and outreach efforts are common tools intended to reduce loss of life and property. It is for these reasons that the PRSN is participating in an effort with local and federal agencies to develop tsunami hazard risk reduction strategies under the NTHMP. This grant supports the TsunamiReady program, which is the base of the tsunami preparedness and mitigation in PR. In order to recognize threatened communities in PR as TsunamiReady by the US NWS, the PR Component of the NTHMP have identified and modeled sources for local, regional and tele-tsunamis and the results of simulations have been used to develop tsunami response plans. The main goal of the PR-NTHMP is to strengthen resilient coastal communities that are prepared for tsunami hazards, and recognize PR as TsunamiReady. Evacuation maps were generated in three phases: First, hypothetical tsunami scenarios of potential underwater earthquakes were developed, and these scenarios were then modeled through during the second phase. The third phase consisted in determining the worst-case scenario based on the Maximum of Maximums (MOM). Inundation and evacuation zones were drawn on GIS referenced maps and aerial photographs. These products are being used by emergency managers to educate the public and develop mitigation strategies. Maps and related evacuation products, like evacuation times, can be accessed online via the PR Tsunami Decision Support Tool. Based on these evacuation maps, tsunami signs were installed, vulnerability profiles were created, communication systems to receive and disseminate tsunami messages were installed in each TWFP, and tsunami response plans were approved. Also, the existing tsunami protocol and criteria in the PR/VI was updated. This paper describes the PR-NTHMP recent outcomes, including the real time monitoring as well as the protocols used to broadcast tsunami messages. The paper highlights tsunami hazards assessment, detection, warning, education and outreach efforts in Puerto Rico.

Rainfall-triggered landslides, anthropogenic hazards, and mitigation strategies

USGS Publications Warehouse

Larsen, M.C.

2008-01-01

Rainfall-triggered landslides are part of a natural process of hillslope erosion that can result in catastrophic loss of life and extensive property damage in mountainous, densely populated areas. As global population expansion on or near steep hillslopes continues, the human and economic costs associated with landslides will increase. Landslide hazard mitigation strategies generally involve hazard assessment mapping, warning systems, control structures, and regional landslide planning and policy development. To be sustainable, hazard mitigation requires that management of natural resources is closely connected to local economic and social interests. A successful strategy is dependent on a combination of multi-disciplinary scientific and engineering approaches, and the political will to take action at the local community to national scale.

New Developments in FPGA Devices: SEUs and Fail-Safe Strategies from the NASA Goddard Perspective

NASA Technical Reports Server (NTRS)

Berg, Melanie; LaBel, Kenneth; Pellish, Jonathan

2016-01-01

It has been shown that, when exposed to radiation environments, each Field Programmable Gate Array (FPGA) device has unique error signatures. Subsequently, fail-safe and mitigation strategies will differ per FPGA type. In this session several design approaches for safe systems will be presented. It will also explore the benefits and limitations of several mitigation techniques. The intention of the presentation is to provide information regarding FPGA types, their susceptibilities, and proven fail-safe strategies; so that users can select appropriate mitigation and perform the required trade for system insertion. The presentation will describe three types of FPGA devices and their susceptibilities in radiation environments.

Impacts of climate mitigation strategies in the energy sector on global land use and carbon balance

NASA Astrophysics Data System (ADS)

Engström, Kerstin; Lindeskog, Mats; Olin, Stefan; Hassler, John; Smith, Benjamin

2017-09-01

Reducing greenhouse gas emissions to limit damage to the global economy climate-change-induced and secure the livelihoods of future generations requires ambitious mitigation strategies. The introduction of a global carbon tax on fossil fuels is tested here as a mitigation strategy to reduce atmospheric CO2 concentrations and radiative forcing. Taxation of fossil fuels potentially leads to changed composition of energy sources, including a larger relative contribution from bioenergy. Further, the introduction of a mitigation strategy reduces climate-change-induced damage to the global economy, and thus can indirectly affect consumption patterns and investments in agricultural technologies and yield enhancement. Here we assess the implications of changes in bioenergy demand as well as the indirectly caused changes in consumption and crop yields for global and national cropland area and terrestrial biosphere carbon balance. We apply a novel integrated assessment modelling framework, combining three previously published models (a climate-economy model, a socio-economic land use model and an ecosystem model). We develop reference and mitigation scenarios based on the narratives and key elements of the shared socio-economic pathways (SSPs). Taking emissions from the land use sector into account, we find that the introduction of a global carbon tax on the fossil fuel sector is an effective mitigation strategy only for scenarios with low population development and strong sustainability criteria (SSP1 Taking the green road). For scenarios with high population growth, low technological development and bioenergy production the high demand for cropland causes the terrestrial biosphere to switch from being a carbon sink to a source by the end of the 21st century.

76 FR 55125 - Finance, Budget & Program Committee Meeting of the Board of Directors; Sunshine Act

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-06

... NEIGHBORHOOD REINVESTMENT CORPORATION Finance, Budget & Program Committee Meeting of the Board of..., Assistant Corporate Secretary, (202) 220-2376; [email protected] . AGENDA: I. CALL TO ORDER II. Financial Report III. Budget Report IV. Lease Update V. Corporate Scorecard VI. National Foreclosure Mitigation...

78 FR 63966 - Notice of Change to the Nation's Tidal Datums With the Adoption of a Modified Procedure for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... boundary determinations, coastal engineering, storm warnings and hazard mitigation, emergency management... shoreline depiction may need to be updated on the next regularly scheduled chart edition. Although... Web site ( http://www.tidesandcurrents.noaa.gov ) or contact the Center for Operational Oceanographic...

Examining the sources of public support for wildland fire policies

Treesearch

J.D. Absher; J.J. Vaske

2007-01-01

Recent severe wildfires have reinforced the need for successful mitigation strategies to be coordinated across all levels of government that address the needs and concerns of homeowners who live in the wildland/urban interface (WUI). Despite the growing body of social science literature on agency-initiated wildland fire policies and homeowner mitigation strategies,...

Nonequivalence of updating rules in evolutionary games under high mutation rates.

PubMed

Kaiping, G A; Jacobs, G S; Cox, S J; Sluckin, T J

2014-10-01

Moran processes are often used to model selection in evolutionary simulations. The updating rule in Moran processes is a birth-death process, i. e., selection according to fitness of an individual to give birth, followed by the death of a random individual. For well-mixed populations with only two strategies this updating rule is known to be equivalent to selecting unfit individuals for death and then selecting randomly for procreation (biased death-birth process). It is, however, known that this equivalence does not hold when considering structured populations. Here we study whether changing the updating rule can also have an effect in well-mixed populations in the presence of more than two strategies and high mutation rates. We find, using three models from different areas of evolutionary simulation, that the choice of updating rule can change model results. We show, e. g., that going from the birth-death process to the death-birth process can change a public goods game with punishment from containing mostly defectors to having a majority of cooperative strategies. From the examples given we derive guidelines indicating when the choice of the updating rule can be expected to have an impact on the results of the model.

Nonequivalence of updating rules in evolutionary games under high mutation rates

NASA Astrophysics Data System (ADS)

Kaiping, G. A.; Jacobs, G. S.; Cox, S. J.; Sluckin, T. J.

2014-10-01

Moran processes are often used to model selection in evolutionary simulations. The updating rule in Moran processes is a birth-death process, i. e., selection according to fitness of an individual to give birth, followed by the death of a random individual. For well-mixed populations with only two strategies this updating rule is known to be equivalent to selecting unfit individuals for death and then selecting randomly for procreation (biased death-birth process). It is, however, known that this equivalence does not hold when considering structured populations. Here we study whether changing the updating rule can also have an effect in well-mixed populations in the presence of more than two strategies and high mutation rates. We find, using three models from different areas of evolutionary simulation, that the choice of updating rule can change model results. We show, e. g., that going from the birth-death process to the death-birth process can change a public goods game with punishment from containing mostly defectors to having a majority of cooperative strategies. From the examples given we derive guidelines indicating when the choice of the updating rule can be expected to have an impact on the results of the model.

Patient-stated preferences regarding volume-related risk mitigation strategies for hemodialysis.

PubMed

Flythe, Jennifer E; Mangione, Thomas W; Brunelli, Steven M; Curhan, Gary C

2014-08-07

Larger weight gain and higher ultrafiltration rates have been associated with poorer outcomes among patients on dialysis. Dietary restrictions reduce fluid-related risk; however, adherence is challenging. Alternative fluid mitigation strategies include treatment time extension, more frequent dialysis, adjunct peritoneal dialysis, and wearable ultrafiltration devices. No data regarding patient preferences for fluid management exist. A survey was designed, tested, and administered to assess patient-stated preferences regarding fluid mitigation. A written survey concerning fluid-related symptoms, patient and treatment characteristics, and fluid management preferences was developed. The cross-sectional survey was completed by 600 patients on hemodialysis at 18 geographically diverse ambulatory facilities. Comparisons of patient willingness to engage in volume mitigation strategies across fluid symptom burden, dietary restriction experience, and patient characteristics were performed. Final analyses included 588 surveys. Overall, if allowed to liberalize fluid intake, 44.6% of patients were willing to extend treatment time by 15 minutes. Willingness to extend treatment time was incrementally less for longer treatment extensions; 12.2% of patients were willing to add a fourth weekly treatment session, and 13.5% of patients were willing to participate in nocturnal dialysis three nights per week. Patients more bothered by their fluid restrictions (versus less bothered) were more willing to engage in fluid mitigation strategies. Demographic characteristics and symptoms, such as cramping and dyspnea, were not consistently associated with willingness to engage in the proposed strategies. More than 25% of patients were unsure of their dry weights and typical interdialytic weight gains. Patients were generally averse to treatment time extension>15 minutes. Patients more bothered (versus less bothered) by their prescribed fluid restrictions were more willing to engage in volume mitigation strategies. Additional study of patient-stated preferences in hemodialysis treatment practices is needed to guide patient care and identify deficiencies in patient treatment and disease-related knowledge. Copyright © 2014 by the American Society of Nephrology.

Threatened and Endangered Species Habitat Management Plan for Los Alamos National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hathcock, Charles Dean; Keller, David Charles; Thompson, Brent E.

Los Alamos National Laboratory’s (LANL) Threatened and Endangered Species Habitat Management Plan (HMP) fulfills a commitment made to the U.S. Department of Energy (DOE) in the “Final Environmental Impact Statement for the Dual-Axis Radiographic Hydrodynamic Test Facility Mitigation Action Plan” (DOE 1996). The HMP received concurrence from the U.S. Fish and Wildlife Service (USFWS) in 1999 (USFWS consultation numbers 2-22-98-I-336 and 2-22-95-I-108). This 2017 update retains the management guidelines from the 1999 HMP for listed species, and updates some descriptive information.

An Updated Examination of Aviation Accidents Associated with Turbulence, Wind Shear and Thunderstorm

NASA Technical Reports Server (NTRS)

Evans, Joni K.

2014-01-01

One of the technical challenges within the Atmospheric Environment Safety Technologies (AEST) Project of the Aviation Safety Program was to "improve and expand remote sensing and mitigation of hazardous atmospheric environments and phenomena"1. In 2012, the author performed an analysis comparing various characteristics of accidents associated with different types of atmospheric hazard environments2. This document reports an update to that analysis which was done in preparation for presenting these findings at the 2015 annual meeting of the Transportation Research Board. Specifically, an additional three years of data were available, and a time-trend analysis was added.

Maximizing mitigation benefits-making a difference with strategic inter-resource agency planning : year two technical report.

DOT National Transportation Integrated Search

2014-11-01

The objective of this research project is to assess current mitigation policies and practices in comparison to : resource agency objectives and to identify mitigation strategies and priorities that provide greater cost-benefit potential and implement...

Maximizing mitigation benefits-making a difference with strategic inter-resource agency planning : year one technical report.

DOT National Transportation Integrated Search

2014-04-01

The objective of this research project is to assess current mitigation policies and practices in comparison to : resource agency objectives, and identify mitigation strategies and priorities that provide greater cost-benefit : potential and implement...

A public health hazard mitigation planning process.

PubMed

Griffith, Jennifer M; Kay Carpender, S; Crouch, Jill Artzberger; Quiram, Barbara J

2014-01-01

The Texas A&M Health Science Center School of Rural Public Health, a member of the Training and Education Collaborative System Preparedness and Emergency Response Learning Center (TECS-PERLC), has long-standing partnerships with 2 Health Service Regions (Regions) in Texas. TECS-PERLC was contracted by these Regions to address 2 challenges identified in meeting requirements outlined by the Risk-Based Funding Project. First, within Metropolitan Statistical Areas, there is not a formal authoritative structure. Second, preexisting tools and processes did not adequately satisfy requirements to assess public health, medical, and mental health needs and link mitigation strategies to the Public Health Preparedness Capabilities, which provide guidance to prepare for, respond to, and recover from public health incidents. TECS-PERLC, with its partners, developed a framework to interpret and apply results from the Texas Public Health Risk Assessment Tool (TxPHRAT). The 3-phase community engagement-based TxPHRAT Mitigation Planning Process (Mitigation Planning Process) and associated tools facilitated the development of mitigation plans. Tools included (1) profiles interpreting TxPHRAT results and identifying, ranking, and prioritizing hazards and capability gaps; (2) a catalog of intervention strategies and activities linked to hazards and capabilities; and (3) a template to plan, evaluate, and report mitigation planning efforts. The Mitigation Planning Process provided a framework for Regions to successfully address all funding requirements. TECS-PERLC developed more than 60 profiles, cataloged and linked 195 intervention strategies, and developed a template resulting in 20 submitted mitigation plans. A public health-focused, community engagement-based mitigation planning process was developed by TECS-PERLC and successfully implemented by the Regions. The outcomes met all requirements and reinforce the effectiveness of academic practice partnerships and importance of community engagement in mitigation planning. Additional funding has been approved to expand the Mitigation Planning Process to all counties in Texas with local health departments.

Hedge math: Theoretical limits on minimum stockpile size across nuclear hedging strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lafleur, Jarret Marshall; Roesler, Alexander W.

2016-09-01

In June 2013, the Department of Defense published a congressionally mandated, unclassified update on the U.S. Nuclear Employment Strategy. Among the many updates in this document are three key ground rules for guiding the sizing of the non-deployed U.S. nuclear stockpile. Furthermore, these ground rules form an important and objective set of criteria against which potential future stockpile hedging strategies can be evaluated.

Mitigation of infectious disease at school: targeted class closure vs school closure.

PubMed

Gemmetto, Valerio; Barrat, Alain; Cattuto, Ciro

2014-12-31

School environments are thought to play an important role in the community spread of infectious diseases such as influenza because of the high mixing rates of school children. The closure of schools has therefore been proposed as an efficient mitigation strategy. Such measures come however with high associated social and economic costs, making alternative, less disruptive interventions highly desirable. The recent availability of high-resolution contact network data from school environments provides an opportunity to design models of micro-interventions and compare the outcomes of alternative mitigation measures. We model mitigation measures that involve the targeted closure of school classes or grades based on readily available information such as the number of symptomatic infectious children in a class. We focus on the specific case of a primary school for which we have high-resolution data on the close-range interactions of children and teachers. We simulate the spread of an influenza-like illness in this population by using an SEIR model with asymptomatics, and compare the outcomes of different mitigation strategies. We find that targeted class closure affords strong mitigation effects: closing a class for a fixed period of time--equal to the sum of the average infectious and latent durations--whenever two infectious individuals are detected in that class decreases the attack rate by almost 70% and significantly decreases the probability of a severe outbreak. The closure of all classes of the same grade mitigates the spread almost as much as closing the whole school. Our model of targeted class closure strategies based on readily available information on symptomatic subjects and on limited information on mixing patterns, such as the grade structure of the school, shows that these strategies might be almost as effective as whole-school closure, at a much lower cost. This may inform public health policies for the management and mitigation of influenza-like outbreaks in the community.

Operational short-term Probabilistic Volcanic Hazard Assessment of tephra fallout: an example from the 1982-1984 unrest at Campi Flegrei

NASA Astrophysics Data System (ADS)

Sandri, Laura; Selva, Jacopo; Costa, Antonio; Macedonio, Giovanni; Marzocchi, Warner

2014-05-01

Probabilistic Volcanic Hazard Assessment (PVHA) represents the most complete scientific contribution for planning rational strategies aimed at mitigating the risk posed by volcanic activity at different time scales. The definition of the space-time window for PVHA is related to the kind of risk mitigation actions that are under consideration. Short intervals (days to weeks) are important for short-term risk mitigation actions like the evacuation of a volcanic area. During volcanic unrest episodes or eruptions, it is of primary importance to produce short-term tephra fallout forecast, and frequently update it to account for the rapidly evolving situation. This information is obviously crucial for crisis management, since tephra may heavily affect building stability, public health, transportations and evacuation routes (airports, trains, road traffic) and lifelines (electric power supply). In this study, we propose a methodology for the short-term PVHA and its operational implementation, based on the model BET_EF, in which measures from the monitoring system are used to routinely update the forecast of some parameters related to the eruption dynamics, that is, the probabilities of eruption, of every possible vent position and every possible eruption size. Then, considering all possible vent positions and eruptive sizes, tephra dispersal models are coupled with frequently updated meteorological forecasts. Finally, these results are merged through a Bayesian procedure, accounting for epistemic uncertainties at all the considered steps. As case study we retrospectively study some stages of the volcanic unrest that took place in Campi Flegrei (CF) in 1982-1984. In particular, we aim at presenting a practical example of possible operational tephra fall PVHA on a daily basis, in the surroundings of CF at different stages of the 1982-84 unrest. Tephra dispersal is simulated using the analytical HAZMAP code. We consider three possible eruptive sizes (a low, a medium and a high eruption "scenario" respectively) and 700 possible vent positions within the CF Neapolitan Yellow Tuff caldera. The probabilities related to eruption dynamics, and estimated by BET_EF, are based on the set up of the code obtained specifically for CF during a 6-years long elicitation project, and on the actual monitoring parameters measured during the unrest and published in the literature. We take advantage here of two novel improvements: (i) a time function to describe how the probability of eruption evolves within the time window defined for the forecast, and (ii) the production of hazard curves and their confidence levels, a tool that allows a complete description of PVHA and its uncertainties. The general goal of this study is to show what, and how, pieces of scientific knowledge can be operationally transferred to decision makers, and specifically how this could have been translated in practice during the 1982-84 Campi Flegrei crisis, if scientists knew what we know today about this volcano.

78 FR 78067 - Focused Mitigation Strategies To Protect Food Against Intentional Adulteration; Public Meeting on...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-24

... Vol. 78 Tuesday, No. 247 December 24, 2013 Part V Department of Health and Human Services Food and Drug Administration 21 CFR Parts 16 and 121 Focused Mitigation Strategies To Protect Food Against... SERVICES Food and Drug Administration 21 CFR Parts 16 and 121 [Docket No. FDA-2013-N-1425] Focused...

Effectiveness of forest management strategies to mitigate effects of global change in south-central Siberia

Treesearch

Eric J. Gustafson; Anatoly Z. Shvidenko; Robert M. Scheller

2011-01-01

We investigated questions about the ability of broad silvicultural strategies to achieve multiple objectives (reduce disturbance losses, maintain the abundance of preferred species, mitigate fragmentation and loss of age-class diversity, and sequester aboveground carbon) under future climate conditions in Siberia. We conducted a factorial experiment using the LANDIS-II...

Farm simulation: a tool for evaluating the mitigation of greenhouse gas emissions and the adaptation of dairy production to climate change

USDA-ARS?s Scientific Manuscript database

Process-level modeling at the farm scale provides a tool for evaluating both strategies for mitigating greenhouse gas emissions and strategies for adapting to climate change. The Integrated Farm System Model (IFSM) simulates representative crop, beef or dairy farms over many years of weather to pred...

Age-related patterns of forest complexity and carbon storage in pine and aspen-birch ecosystems of northern Minnesota, USA

Treesearch

John B. Bradford; Douglas N. Kastendick

2010-01-01

Forest managers are seeking strategies to create stands that can adapt to new climatic conditions and simultaneously help mitigate increases in atmospheric CO2. Adaptation strategies often focus on enhancing resilience by maximizing forest complexity in terms of species composition and size structure, while mitigation involves sustaining carbon...

Risk Assessment and Integration Team (RAIT) Portfolio Risk Analysis Strategy

NASA Technical Reports Server (NTRS)

Edwards, Michelle

2010-01-01

Impact at management level: Qualitative assessment of risk criticality in conjunction with risk consequence, likelihood, and severity enable development of an "investment policy" towards managing a portfolio of risks. Impact at research level: Quantitative risk assessments enable researchers to develop risk mitigation strategies with meaningful risk reduction results. Quantitative assessment approach provides useful risk mitigation information.

Effectiveness of Internal vs. External SEU Scrubbing Mitigation Strategies in a Xilinx FPGA: Design, Test, and Analysis

NASA Technical Reports Server (NTRS)

Berg, Melanie; Poivey C.; Petrick, D.; Espinosa, D.; Lesea, Austin; LaBel, K. A.; Friendlich, M; Kim, H; Phan, A.

2008-01-01

We compare two scrubbing mitigation schemes for Xilinx FPGA devices. The design of the scrubbers is briefly discussed along with an examination of mitigation limitations. Proton and Heavy Ion data are then presented and analyzed.

Young and Older Adults’ Beliefs about Effective Ways to Mitigate Age-Related Memory Decline

PubMed Central

Horhota, Michelle; Lineweaver, Tara; Ositelu, Monique; Summers, Kristi; Hertzog, Christopher

2013-01-01

This study investigated whether young and older adults vary in their beliefs about the impact of various mitigating factors on age-related memory decline. Eighty young (ages 18–23) and eighty older (ages 60–82) participants reported their beliefs about their own memory abilities and the strategies that they use in their everyday lives to attempt to control their memory. Participants also reported their beliefs about memory change with age for hypothetical target individuals who were described as using (or not using) various means to mitigate memory decline. There were no age differences in personal beliefs about control over current or future memory ability. However, the two age groups differed in the types of strategies they used in their everyday life to control their memory. Young adults were more likely to use internal memory strategies, whereas older adults were more likely to focus on cognitive exercise and maintaining physical health as ways to optimize their memory ability. There were no age differences in rated memory change across the life span in hypothetical individuals. Both young and older adults perceived strategies related to improving physical and cognitive health as effective means of mitigating memory loss with age, whereas internal memory strategies were perceived as less effective means for controlling age-related memory decline. PMID:22082012

Urban cross-sector actions for carbon mitigation with local health co-benefits in China

NASA Astrophysics Data System (ADS)

Ramaswami, Anu; Tong, Kangkang; Fang, Andrew; Lal, Raj M.; Nagpure, Ajay Singh; Li, Yang; Yu, Huajun; Jiang, Daqian; Russell, Armistead G.; Shi, Lei; Chertow, Marian; Wang, Yangjun; Wang, Shuxiao

2017-10-01

Cities offer unique strategies to reduce fossil fuel use through the exchange of energy and materials across homes, businesses, infrastructure and industries co-located in urban areas. However, the large-scale impact of such strategies has not been quantified. Using new models and data sets representing 637 Chinese cities, we find that such cross-sectoral strategies--enabled by compact urban design and circular economy policies--contribute an additional 15%-36% to national CO2 mitigation, compared to conventional single-sector strategies. As a co-benefit, ~25,500 to ~57,500 deaths annually are avoided from air pollution reduction. The benefits are highly variable across cities, ranging from <1%-37% for CO2 emission reduction and <1%-47% for avoided premature deaths. These results, using multi-scale, multi-sector physical systems modelling, identify cities with high carbon and health co-benefit potential and show that urban-industrial symbiosis is a significant carbon mitigation strategy, achievable with a combination of existing and advanced technologies in diverse city types.

Methanogens: Methane Producers of the Rumen and Mitigation Strategies

PubMed Central

Hook, Sarah E.; Wright, André-Denis G.; McBride, Brian W.

2010-01-01

Methanogens are the only known microorganisms capable of methane production, making them of interest when investigating methane abatement strategies. A number of experiments have been conducted to study the methanogen population in the rumen of cattle and sheep, as well as the relationship that methanogens have with other microorganisms. The rumen methanogen species differ depending on diet and geographical location of the host, as does methanogenesis, which can be reduced by modifying dietary composition, or by supplementation of monensin, lipids, organic acids, or plant compounds within the diet. Other methane abatement strategies that have been investigated are defaunation and vaccines. These mitigation methods target the methanogen population of the rumen directly or indirectly, resulting in varying degrees of efficacy. This paper describes the methanogens identified in the rumens of cattle and sheep, as well as a number of methane mitigation strategies that have been effective in vivo. PMID:21253540

Fuel Flexibility: Landfill Gas Contaminant Mitigation for Power Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Storey, John Morse; Theiss, Timothy J; Kass, Michael D

This research project focused on the mitigation of silica damage to engine-based renewable landfill gas energy systems. Characterization of the landfill gas siloxane contamination, combined with characterization of the silica deposits in engines, led to development of two new mitigation strategies. The first involved a novel method for removing the siloxanes and other heavy contaminants from the landfill gas prior to use by the engines. The second strategy sought to interrupt the formation of hard silica deposits in the engine itself, based on inspection of failed landfill gas engine parts. In addition to mitigation, the project had a third taskmore » to develop a robust sensor for siloxanes that could be used to control existing and/or future removal processes.« less

Mitigation of methane emissions in cities: How new measurements and partnerships can contribute to emissions reduction strategies

DOE PAGES

Hopkins, Francesca M.; Ehleringer, James R.; Bush, Susan E.; ...

2016-09-10

Cities generate 70% of anthropogenic greenhouse gas emissions, a fraction that is grow-ing with global urbanization. While cities play an important role in climate change mitigation, there has been little focus on reducing urban methane (CH4) emissions. Here, we develop a conceptual framework for CH 4 mitigation in cities by describing emission processes, the role of measurements, and a need for new institutional partnerships. Urban CH 4 emissions are likely to grow with expanding use of natural gas and organic waste disposal systems in growing population centers; however, we currently lack the ability to quantify this increase. We also lackmore » systematic knowledge of the relative contribution of these distinct source sectors on emissions. We present new observations from four North American cities to demonstrate that CH4 emissions vary in magnitude and sector from city to city and hence require different mitigation strategies. Detections of fugitive emissions from these systems suggest that current mitiga- tion approaches are absent or ineffective. These findings illustrate that tackling urban CH 4 emissions will require research efforts to identify mitigation targets, develop and implement new mitigation strategies, and monitor atmospheric CH 4 levels to ensure the success of mitigation efforts. This research will require a variety of techniques to achieve these objectives and should be deployed in cities globally. In conclusion, we suggest that metropolitan scale partnerships may effectively coordinate systematic measurements and actions focused on emission reduction goals.« less

Mitigation of methane emissions in cities: How new measurements and partnerships can contribute to emissions reduction strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hopkins, Francesca M.; Ehleringer, James R.; Bush, Susan E.

Cities generate 70% of anthropogenic greenhouse gas emissions, a fraction that is grow-ing with global urbanization. While cities play an important role in climate change mitigation, there has been little focus on reducing urban methane (CH4) emissions. Here, we develop a conceptual framework for CH 4 mitigation in cities by describing emission processes, the role of measurements, and a need for new institutional partnerships. Urban CH 4 emissions are likely to grow with expanding use of natural gas and organic waste disposal systems in growing population centers; however, we currently lack the ability to quantify this increase. We also lackmore » systematic knowledge of the relative contribution of these distinct source sectors on emissions. We present new observations from four North American cities to demonstrate that CH4 emissions vary in magnitude and sector from city to city and hence require different mitigation strategies. Detections of fugitive emissions from these systems suggest that current mitiga- tion approaches are absent or ineffective. These findings illustrate that tackling urban CH 4 emissions will require research efforts to identify mitigation targets, develop and implement new mitigation strategies, and monitor atmospheric CH 4 levels to ensure the success of mitigation efforts. This research will require a variety of techniques to achieve these objectives and should be deployed in cities globally. In conclusion, we suggest that metropolitan scale partnerships may effectively coordinate systematic measurements and actions focused on emission reduction goals.« less

Nonzero-Sum Relationships in Mitigating Urban Carbon Emissions: A Dynamic Network Simulation.

PubMed

Chen, Shaoqing; Chen, Bin; Su, Meirong

2015-10-06

The "stove-pipe" way of thinking has been mostly used in mitigating carbon emissions and managing socioeconomics because of its convenience of implementation. However, systems-oriented approaches become imperative in pursuit of an efficient regulation of carbon emissions from systems as complicated as urban systems. The aim of this paper is to establish a dynamic network approach that is capable of assessing the effectiveness of carbon emissions mitigation in a more holistic way. A carbon metabolic network is constructed by modeling the carbon flows between economic sectors and environment. With the network shocked by interventions to the sectoral carbon flows, indirect emissions from the city are accounted for under certain carbon mitigation strategies. The nonzero-sum relationships between sectors and environmental components are identified based on utility analysis, which synthesize the nature of direct and indirect network interactions. The results of the case study of Beijing suggest that the stove-pipe mitigation strategies targeted the economic sectors might be not as efficient as they were expected. A direct cutting in material or energy import to the sectors may result in a rebound in indirect emissions and thus fails to achieve the carbon mitigation goal of the city as a whole. A promising way of foreseeing the dynamic mechanism of emissions is to analyze the nonzero-sum relationships between important urban components. Thinking cities as systems of interactions, the network approach is potentially a strong tool for appraising and filtering mitigation strategies of carbon emissions.

Electrons and photons at High Level Trigger in CMS for Run II

NASA Astrophysics Data System (ADS)

Anuar, Afiq A.

2015-12-01

The CMS experiment has been designed with a 2-level trigger system. The first level is implemented using custom-designed electronics. The second level is the so-called High Level Trigger (HLT), a streamlined version of the CMS offline reconstruction software running on a computer farm. For Run II of the Large Hadron Collider, the increase in center-of-mass energy and luminosity will raise the event rate to a level challenging for the HLT algorithms. New approaches have been studied to keep the HLT output rate manageable while maintaining thresholds low enough to cover physics analyses. The strategy mainly relies on porting online the ingredients that have been successfully applied in the offline reconstruction, thus allowing to move HLT selection closer to offline cuts. Improvements in HLT electron and photon definitions will be presented, focusing in particular on: updated clustering algorithm and the energy calibration procedure, new Particle-Flow-based isolation approach and pileup mitigation techniques, and the electron-dedicated track fitting algorithm based on Gaussian Sum Filter.

Generation of intervention strategy for a genetic regulatory network represented by a family of Markov Chains.

PubMed

Berlow, Noah; Pal, Ranadip

2011-01-01

Genetic Regulatory Networks (GRNs) are frequently modeled as Markov Chains providing the transition probabilities of moving from one state of the network to another. The inverse problem of inference of the Markov Chain from noisy and limited experimental data is an ill posed problem and often generates multiple model possibilities instead of a unique one. In this article, we address the issue of intervention in a genetic regulatory network represented by a family of Markov Chains. The purpose of intervention is to alter the steady state probability distribution of the GRN as the steady states are considered to be representative of the phenotypes. We consider robust stationary control policies with best expected behavior. The extreme computational complexity involved in search of robust stationary control policies is mitigated by using a sequential approach to control policy generation and utilizing computationally efficient techniques for updating the stationary probability distribution of a Markov chain following a rank one perturbation.

Cargo-Delivery Platforms for Targeted Delivery of Inhibitor Cargos Against Botulism

PubMed Central

Wilson, Brenda A.; Ho, Mengfei

2015-01-01

Delivering therapeutic cargos to specific cell types in vivo poses many technical challenges. There is currently a plethora of drug leads and therapies against numerous diseases, ranging from small molecule compounds to nucleic acids to peptides to proteins with varying binding or enzymatic functions. Many of these candidate therapies have documented potential for mitigating or reversing disease symptoms, if only a means for gaining access to the intracellular target were available. Recent advances in our understanding of the biology of cellular uptake and transport processes and the mode of action of bacterial protein toxins have accelerated the development of toxin-based cargo-delivery vehicle platforms. This review provides an updated survey of the status of available platforms for targeted delivery of therapeutic cargos, outlining various strategies that have been used to deliver different types of cargo into cells. Particular emphasis is placed on the application of toxin-based approaches, examining critical issues that have hampered realization of post-intoxication antitoxins against botulism. PMID:25335885

Cargo-delivery platforms for targeted delivery of inhibitor cargos against botulism.

PubMed

Wilson, Brenda A; Ho, Mengfei

2014-01-01

Delivering therapeutic cargos to specific cell types in vivo poses many technical challenges. There is currently a plethora of drug leads and therapies against numerous diseases, ranging from small molecule compounds to nucleic acids to peptides to proteins with varying binding or enzymatic functions. Many of these candidate therapies have documented potential for mitigating or reversing disease symptoms, if only a means for gaining access to the intracellular target were available. Recent advances in our understanding of the biology of cellular uptake and transport processes and the mode of action of bacterial protein toxins have accelerated the development of toxin-based cargo-delivery vehicle platforms. This review provides an updated survey of the status of available platforms for targeted delivery of therapeutic cargos, outlining various strategies that have been used to deliver different types of cargo into cells. Particular emphasis is placed on the application of toxin-based approaches, examining critical issues that have hampered realization of post-intoxication antitoxins against botulism.

Copolyimide Surface Modifying Agents for Particle Adhesion Mitigation

NASA Technical Reports Server (NTRS)

Wohl, Christopher J.; Connell, John W.

2011-01-01

Marine biofouling, insect adhesion on aircraft surfaces, microbial contamination of sterile environments, and particle contamination all present unique challenges for which researchers have adopted an array of mitigation strategies. Particulate contamination is of interest to NASA regarding exploration of the Moon, Mars, asteroids, etc.1 Lunar dust compromised seals, clogged filters, abraded visors and space suit surfaces, and was a significant health concern during the Apollo missions.2 Consequently, NASA has instituted a multi-faceted approach to address dust including use of sacrificial surfaces, active mitigation requiring the use of an external energy source, and passive mitigation utilizing materials with an intrinsic resistance to surface contamination. One passive mitigation strategy is modification of a material s surface energy either chemically or topographically. The focus of this paper is the synthesis and evaluation of novel copolyimide materials with surface modifying agents (SMA, oxetanes) enabling controlled variation of surface chemical composition.

Inmate Sexual Aggression: Some Evolving Propositions, Empirical Findings, and Mitigating Counter-Forces.

ERIC Educational Resources Information Center

Nacci, Peter L.; Kane, Thomas R.

1984-01-01

Updates the US Bureau of Prisons' investigation of inmate sexual aggression, and contrasts findings from the federal study with other reports. Discusses the Federal Bureau of Prisons' policy on homosexual activity and family visitation programs and describes some processes in corrections which will make prisons generally safer. (JAC)

7 CFR 319.56-50 - Hass avocados from Peru.

Code of Federal Regulations, 2011 CFR

2011-01-01

... production to remain eligible to export avocados to the United States. The NPPO of Peru must keep records of fruit fly detections for each trap, update the records each time the traps are checked, and make the records available to APHIS inspectors upon request. (e) Mitigation measures for C. capitata. Places of...

78 FR 39057 - Environmental Impact Statement: T.F. Green Airport, Warwick, Rhode Island

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

... of Availability. SUMMARY: The FAA is issuing this notice to advise the public that a Written Re..., Burlington, MA 01803, (781) 238-7613, or at [email protected]gov . SUPPLEMENTARY INFORMATION: The FAA has issued a Written Re-Evaluation and Record of Decision, which evaluates an updated noise mitigation...

Ammonia emission mitigation in food waste composting: A review.

PubMed

Wang, Shuguang; Zeng, Yang

2018-01-01

Composting is a reliable technology to treat food waste (FW) and produce high quality compost. The ammonia (NH 3 ) emission accounts for the largest nitrogen loss and leads to various environmental impacts. This review introduced the recent progresses on NH 3 mitigation in FW composting. The basic characteristics of FW from various sources were given. Seven NH 3 emission strategies proven effective in the literature were presented. The links between these strategies and the mechanisms of NH 3 production were addressed. Application of hydrothermally treated C rich substrates, biochar or struvite salts had a broad prospect in FW composting if these strategies were proven cost-effective enough. Regulation of nitrogen assimilation and nitrification using biological additive had the potential to achieve NH 3 mitigation but the existing evidence was not enough. In the end, the future prospects highlighted four research topics that needed further investigation to improve NH 3 mitigation and nitrogen conservation in FW composting. Copyright © 2017 Elsevier Ltd. All rights reserved.

Water conservation benefits of urban heat mitigation.

PubMed

Vahmani, Pouya; Jones, Andrew D

2017-10-20

Many cities globally are seeking strategies to counter the consequences of both a hotter and drier climate. While urban heat mitigation strategies have been shown to have beneficial effects on health, energy consumption, and greenhouse gas emissions, their implications for water conservation have not been widely examined. Here we use a suite of satellite-supported regional climate simulations in California to show that broad implementation of cool roofs, a heat mitigation strategy, not only results in significant cooling, but can also meaningfully decrease outdoor water consumption by reducing evaporative and irrigation water demands. Irrigation water consumption across the major metropolitan areas is reduced by up to 9% and irrigation water savings per capita range from 1.8 to 15.4 gallons per day across 18 counties examined. Total water savings are found to be the highest in Los Angeles county, reaching about 83 million gallons per day. Cool roofs are a valuable solution for addressing the adaptation and mitigation challenges faced by multiple sectors in California.

Pain management and opioid risk mitigation in the military.

PubMed

Sharpe Potter, Jennifer; Bebarta, Vikhyat S; Marino, Elise N; Ramos, Rosemarie G; Turner, Barbara J

2014-05-01

Opioid analgesics misuse is a significant military health concern recognized as a priority issue by military leadership. Opioids are among those most commonly prescribed medications in the military for pain management. The military has implemented opioid risk mitigation strategies, including the Sole Provider Program and the Controlled Drug Management Analysis and Reporting Tool, which are used to identify and monitor for risk and misuse. However, there are substantial opportunities to build on these existing systems to better ensure safer opioid prescribing and monitor for misuse. Opioid risk mitigation strategies implemented by the civilian sector include establishing clinical guidelines for opioid prescribing and prescription monitoring programs. These strategies may help to inform opioid risk mitigation in the military health system. Reducing the risk of opioid misuse and improving quality of care for our Warfighters is necessary. This must be done through evidence-based approaches with an investment in research to improve patient care and prevent opioid misuse as well as its sequelae. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.

Water conservation benefits of urban heat mitigation

DOE PAGES

Vahmani, Pouya; Jones, Andrew D.

2017-10-20

Many cities globally are seeking strategies to counter the consequences of both a hotter and drier climate. While urban heat mitigation strategies have been shown to have beneficial effects on health, energy consumption, and greenhouse gas emissions, their implications for water conservation have not been widely examined. Here we use a suite of satellite-supported regional climate simulations in California to show that broad implementation of cool roofs, a heat mitigation strategy, not only results in significant cooling, but can also meaningfully decrease outdoor water consumption by reducing evaporative and irrigation water demands. Irrigation water consumption across the major metropolitan areasmore » is reduced by up to 9% and irrigation water savings per capita range from 1.8 to 15.4 gallons per day across 18 counties examined. Total water savings are found to be the highest in Los Angeles county, reaching about 83 million gallons per day. Cool roofs are a valuable solution for addressing the adaptation and mitigation challenges faced by multiple sectors in California.« less

Water conservation benefits of urban heat mitigation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vahmani, Pouya; Jones, Andrew D.

Many cities globally are seeking strategies to counter the consequences of both a hotter and drier climate. While urban heat mitigation strategies have been shown to have beneficial effects on health, energy consumption, and greenhouse gas emissions, their implications for water conservation have not been widely examined. Here we use a suite of satellite-supported regional climate simulations in California to show that broad implementation of cool roofs, a heat mitigation strategy, not only results in significant cooling, but can also meaningfully decrease outdoor water consumption by reducing evaporative and irrigation water demands. Irrigation water consumption across the major metropolitan areasmore » is reduced by up to 9% and irrigation water savings per capita range from 1.8 to 15.4 gallons per day across 18 counties examined. Total water savings are found to be the highest in Los Angeles county, reaching about 83 million gallons per day. Cool roofs are a valuable solution for addressing the adaptation and mitigation challenges faced by multiple sectors in California.« less

Dissociable cognitive mechanisms underlying human path integration.

PubMed

Wiener, Jan M; Berthoz, Alain; Wolbers, Thomas

2011-01-01

Path integration is a fundamental mechanism of spatial navigation. In non-human species, it is assumed to be an online process in which a homing vector is updated continuously during an outward journey. In contrast, human path integration has been conceptualized as a configural process in which travelers store working memory representations of path segments, with the computation of a homing vector only occurring when required. To resolve this apparent discrepancy, we tested whether humans can employ different path integration strategies in the same task. Using a triangle completion paradigm, participants were instructed either to continuously update the start position during locomotion (continuous strategy) or to remember the shape of the outbound path and to calculate home vectors on basis of this representation (configural strategy). While overall homing accuracy was superior in the configural condition, participants were quicker to respond during continuous updating, strongly suggesting that homing vectors were computed online. Corroborating these findings, we observed reliable differences in head orientation during the outbound path: when participants applied the continuous updating strategy, the head deviated significantly from straight ahead in direction of the start place, which can be interpreted as a continuous motor expression of the homing vector. Head orientation-a novel online measure for path integration-can thus inform about the underlying updating mechanism already during locomotion. In addition to demonstrating that humans can employ different cognitive strategies during path integration, our two-systems view helps to resolve recent controversies regarding the role of the medial temporal lobe in human path integration.

Defending Planet Earth: Near-Earth Object Surveys and Hazard Mitigation Strategies

NASA Technical Reports Server (NTRS)

2010-01-01

The United States spends approximately four million dollars each year searching for near-Earth objects (NEOs). The objective is to detect those that may collide with Earth. The majority of this funding supports the operation of several observatories that scan the sky searching for NEOs. This, however, is insufficient in detecting the majority of NEOs that may present a tangible threat to humanity. A significantly smaller amount of funding supports ways to protect the Earth from such a potential collision or "mitigation." In 2005, a Congressional mandate called for NASA to detect 90 percent of NEOs with diameters of 140 meters of greater by 2020. Defending Planet Earth: Near-Earth Object Surveys and Hazard Mitigation Strategies identifies the need for detection of objects as small as 30 to 50 meters as these can be highly destructive. The book explores four main types of mitigation including civil defense, "slow push" or "pull" methods, kinetic impactors and nuclear explosions. It also asserts that responding effectively to hazards posed by NEOs requires national and international cooperation. Defending Planet Earth: Near-Earth Object Surveys and Hazard Mitigation Strategies is a useful guide for scientists, astronomers, policy makers and engineers.

Carbon farming economics: What have we learned?

PubMed

Tang, Kai; Kragt, Marit E; Hailu, Atakelty; Ma, Chunbo

2016-05-01

This study reviewed 62 economic analyses published between 1995 and 2014 on the economic impacts of policies that incentivise agricultural greenhouse (GHG) mitigation. Typically, biophysical models are used to evaluate the changes in GHG mitigation that result from landholders changing their farm and land management practices. The estimated results of biophysical models are then integrated with economic models to simulate the costs of different policy scenarios to production systems. The cost estimates vary between $3 and $130/t CO2 equivalent in 2012 US dollars, depending on the mitigation strategies, spatial locations, and policy scenarios considered. Most studies assessed the consequences of a single, rather than multiple, mitigation strategies, and few considered the co-benefits of carbon farming. These omissions could challenge the reality and robustness of the studies' results. One of the biggest challenges facing agricultural economists is to assess the full extent of the trade-offs involved in carbon farming. We need to improve our biophysical knowledge about carbon farming co-benefits, predict the economic impacts of employing multiple strategies and policy incentives, and develop the associated integrated models, to estimate the full costs and benefits of agricultural GHG mitigation to farmers and the rest of society. Copyright © 2016 Elsevier Ltd. All rights reserved.

Policy intervention for arsenic mitigation in drinking water in rural habitations in India: achievements and challenges.

PubMed

Shrivastava, Brajesh K

2016-10-01

This article provides updated status of the arsenic affected rural habitations in India, summarizes the policy initiatives of the Ministry of Drinking Water & Sanitation (Government of India), reviews the technologies for arsenic treatment and analyses the progress made by states in tackling arsenic problems in rural habitations. It also provides a list of constraints based on experiences and recommends suggested measures to tackle arsenic problems in an holistic manner. It is expected that the paper would be useful for policy formulators in states, non-government organizations, researchers of academic and scientific institutions and programme managers working in the area of arsenic mitigation in drinking water, especially in developing countries, as it provides better insights compared to other available information in India on mitigating arsenic problems in drinking water in rural areas.

Defense Science And Technology: Further DOD And DOE Actions Needed to Provide Timely Conference Decisions and Analyze Risks from Changes in Participation

DTIC Science & Technology

2015-03-01

Conference Planning and Food and Beverage Costs, Audit Report 11-43 (October 2011). 5White House, Executive Order 13589, Promoting Efficient Spending, 76...and conducted a content analysis of these interviews. Based on this analysis, we enumerated challenges and mitigation strategies as well as benefits...of officials, asking respondents to rate the effect of each potential mitigation strategy and prioritize steps for implementing the strategies . We

The effect of healthcare environments on a pandemic influenza outbreak.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cannon, Daniel C.; Davey, Victoria J.; Glass, Robert John, Jr.

The objectives of this presentation are: (1) To determine if healthcare settings serve as intensive transmission environments for influenza epidemics, increasing effects on communities; (2) To determine which mitigation strategies are best for use in healthcare settings and in communities to limit influenza epidemic effects; and (3) To determine which mitigation strategies are best to prevent illness in healthcare workers.

Mitigating IASCC of Reactor Core Internals by Post-Irradiation Annealing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Was, Gary

This final report summarizes research performed during the period between September 2012 and December 2016, with the objective of establishing the effectiveness of post-irradiation annealing (PIA) as an advanced mitigation strategy for irradiation-assisted stress corrosion cracking (IASCC). This was completed by using irradiated 304SS control blade material to conduct crack initiation and crack growth rate (CGR) experiments in simulated BWR environment. The mechanism by which PIA affects IASCC susceptibility will also be verified. The success of this project will provide a foundation for the use of PIA as a mitigation strategy for core internal components in commercial reactors.

The Value of Linking Mitigation and Adaptation: A Case Study of Bangladesh

NASA Astrophysics Data System (ADS)

Ayers, Jessica M.; Huq, Saleemul

2009-05-01

There are two principal strategies for managing climate change risks: mitigation and adaptation. Until recently, mitigation and adaptation have been considered separately in both climate change science and policy. Mitigation has been treated as an issue for developed countries, which hold the greatest responsibility for climate change, while adaptation is seen as a priority for the South, where mitigative capacity is low and vulnerability is high. This conceptual divide has hindered progress against the achievement of the fundamental sustainable development challenges of climate change. Recent attention to exploring the synergies between mitigation and adaptation suggests that an integrated approach could go some way to bridging the gap between the development and adaptation priorities of the South and the need to achieve global engagement in mitigation. These issues are explored through a case study analysis of climate change policy and practice in Bangladesh. Using the example of waste-to-compost projects, a mitigation-adaptation-development nexus is demonstrated, as projects contribute to mitigation through reducing methane emissions; adaptation through soil improvement in drought-prone areas; and sustainable development, because poverty is exacerbated when climate change reduces the flows of ecosystem services. Further, linking adaptation to mitigation makes mitigation action more relevant to policymakers in Bangladesh, increasing engagement in the international climate change agenda in preparation for a post-Kyoto global strategy. This case study strengthens the argument that while combining mitigation and adaptation is not a magic bullet for climate policy, synergies, particularly at the project level, can contribute to the sustainable development goals of climate change and are worth exploring.

The value of linking mitigation and adaptation: a case study of Bangladesh.

PubMed

Ayers, Jessica M; Huq, Saleemul

2009-05-01

There are two principal strategies for managing climate change risks: mitigation and adaptation. Until recently, mitigation and adaptation have been considered separately in both climate change science and policy. Mitigation has been treated as an issue for developed countries, which hold the greatest responsibility for climate change, while adaptation is seen as a priority for the South, where mitigative capacity is low and vulnerability is high. This conceptual divide has hindered progress against the achievement of the fundamental sustainable development challenges of climate change. Recent attention to exploring the synergies between mitigation and adaptation suggests that an integrated approach could go some way to bridging the gap between the development and adaptation priorities of the South and the need to achieve global engagement in mitigation. These issues are explored through a case study analysis of climate change policy and practice in Bangladesh. Using the example of waste-to-compost projects, a mitigation-adaptation-development nexus is demonstrated, as projects contribute to mitigation through reducing methane emissions; adaptation through soil improvement in drought-prone areas; and sustainable development, because poverty is exacerbated when climate change reduces the flows of ecosystem services. Further, linking adaptation to mitigation makes mitigation action more relevant to policymakers in Bangladesh, increasing engagement in the international climate change agenda in preparation for a post-Kyoto global strategy. This case study strengthens the argument that while combining mitigation and adaptation is not a magic bullet for climate policy, synergies, particularly at the project level, can contribute to the sustainable development goals of climate change and are worth exploring.

A Dynamic Model for the Evaluation of Aircraft Engine Icing Detection and Control-Based Mitigation Strategies

NASA Technical Reports Server (NTRS)

Simon, Donald L.; Rinehart, Aidan W.; Jones, Scott M.

2017-01-01

Aircraft flying in regions of high ice crystal concentrations are susceptible to the buildup of ice within the compression system of their gas turbine engines. This ice buildup can restrict engine airflow and cause an uncommanded loss of thrust, also known as engine rollback, which poses a potential safety hazard. The aviation community is conducting research to understand this phenomena, and to identify avoidance and mitigation strategies to address the concern. To support this research, a dynamic turbofan engine model has been created to enable the development and evaluation of engine icing detection and control-based mitigation strategies. This model captures the dynamic engine response due to high ice water ingestion and the buildup of ice blockage in the engines low pressure compressor. It includes a fuel control system allowing engine closed-loop control effects during engine icing events to be emulated. The model also includes bleed air valve and horsepower extraction actuators that, when modulated, change overall engine operating performance. This system-level model has been developed and compared against test data acquired from an aircraft turbofan engine undergoing engine icing studies in an altitude test facility and also against outputs from the manufacturers customer deck. This paper will describe the model and show results of its dynamic response under open-loop and closed-loop control operating scenarios in the presence of ice blockage buildup compared against engine test cell data. Planned follow-on use of the model for the development and evaluation of icing detection and control-based mitigation strategies will also be discussed. The intent is to combine the model and control mitigation logic with an engine icing risk calculation tool capable of predicting the risk of engine icing based on current operating conditions. Upon detection of an operating region of risk for engine icing events, the control mitigation logic will seek to change the engines operating point to a region of lower risk through the modulation of available control actuators while maintaining the desired engine thrust output. Follow-on work will assess the feasibility and effectiveness of such control-based mitigation strategies.

A regional assessment of the cost and effectiveness of mitigation measures for reducing nutrient losses to water and greenhouse gas emissions to air from pastoral farms.

PubMed

Vibart, Ronaldo; Vogeler, Iris; Dennis, Samuel; Kaye-Blake, William; Monaghan, Ross; Burggraaf, Vicki; Beautrais, Josef; Mackay, Alec

2015-06-01

Using a novel approach that links geospatial land resource information with individual farm-scale simulation, we conducted a regional assessment of nitrogen (N) and phosphorous (P) losses to water and greenhouse gas (GHG) emissions to air from the predominant mix of pastoral industries in Southland, New Zealand. An evaluation of the cost-effectiveness of several nutrient loss mitigation strategies applied at the farm-scale, set primarily for reducing N and P losses and grouped by capital cost and potential ease of adoption, followed an initial baseline assessment. Grouped nutrient loss mitigation strategies were applied on an additive basis on the assumption of full adoption, and were broadly identified as 'improved nutrient management' (M1), 'improved animal productivity' (M2), and 'restricted grazing' (M3). Estimated annual nitrate-N leaching losses occurring under representative baseline sheep and beef (cattle) farms, and representative baseline dairy farms for the region were 10 ± 2 and 32 ± 6 kg N/ha (mean ± standard deviation), respectively. Both sheep and beef and dairy farms were responsive to N leaching loss mitigation strategies in M1, at a low cost per kg N-loss mitigated. Only dairy farms were responsive to N leaching loss abatement from adopting M2, at no additional cost per kg N-loss mitigated. Dairy farms were also responsive to N leaching loss abatement from adopting M3, but this reduction came at a greater cost per kg N-loss mitigated. Only dairy farms were responsive to P-loss mitigation strategies, in particular by adopting M1. Only dairy farms were responsive to GHG abatement; greater abatement was achieved by the most intensified dairy farm system simulated. Overall, M1 provided for high levels of regional scale N- and P-loss abatement at a low cost per farm without affecting overall farm production, M2 provided additional N-loss abatement but only marginal P-loss abatement, whereas M3 provided the greatest N-loss abatement, but delivered no additional P abatement, and came at a large financial cost to farmers, sheep and beef farmers in particular. The modelling approach provides a farm-scale framework that can be extended to other regions to accommodate different farm production systems and performances, capturing the interactions between farm types, land use capabilities and production levels, as these influence nutrient losses and GHG emissions, and the effectiveness of mitigation strategies. Copyright © 2015 Elsevier Ltd. All rights reserved.

Overview of Risk Mitigation for Safety-Critical Computer-Based Systems

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

2015-01-01

This report presents a high-level overview of a general strategy to mitigate the risks from threats to safety-critical computer-based systems. In this context, a safety threat is a process or phenomenon that can cause operational safety hazards in the form of computational system failures. This report is intended to provide insight into the safety-risk mitigation problem and the characteristics of potential solutions. The limitations of the general risk mitigation strategy are discussed and some options to overcome these limitations are provided. This work is part of an ongoing effort to enable well-founded assurance of safety-related properties of complex safety-critical computer-based aircraft systems by developing an effective capability to model and reason about the safety implications of system requirements and design.

Analyzing costs of space debris mitigation methods

NASA Astrophysics Data System (ADS)

Wiedemann, C.; Krag, H.; Bendisch, J.; Sdunnus, H.

2004-01-01

The steadily increasing number of space objects poses a considerable hazard to all kinds of spacecraft. To reduce the risks to future space missions different debris mitigation measures and spacecraft protection techniques have been investigated during the last years. However, the economic efficiency has not been considered yet in this context. Current studies have the objective to evaluate the mission costs due to space debris in a business as usual (no mitigation) scenario compared to the missions costs considering debris mitigation. The aim is an estimation of the time until the investment in debris mitigation will lead to an effective reduction of mission costs. This paper presents the results of investigations on the key issues of cost estimation for spacecraft and the influence of debris mitigation and shielding on cost. Mitigation strategies like the reduction of orbital lifetime and de- or re-orbit of non-operational satellites are methods to control the space debris environment. These methods result in an increase of costs. In a first step the overall costs of different types of unmanned satellites are analyzed. A selected cost model is simplified and generalized for an application on all operational satellites. In a next step the influence of space debris on cost is treated, if the implementation of mitigation strategies is considered.

Water conservation benefits of urban heat mitigation: can cooling strategies reduce water consumption in California?

NASA Astrophysics Data System (ADS)

Vahmani, P.; Jones, A. D.

2017-12-01

Urban areas are at the forefront of climate mitigation and adaptation efforts given their high concentration of people, industry, and infrastructure. Many cities globally are seeking strategies to counter the consequences of both a hotter and drier climate. While urban heat mitigation strategies have been shown to have beneficial effects on health, energy consumption, and greenhouse gas emissions, their implications for water conservation have not been widely examined. Here we show that broad implementation of cool roofs, an urban heat mitigation strategy, not only results in significant cooling of air temperature, but also meaningfully decreases outdoor water consumption by reducing evaporative and irrigation water demands. Based on a suite of satellite-supported, multiyear regional climate simulations, we find that cool roof adoption has the potential to reduce outdoor water consumption across the major metropolitan areas in California by up to 9%. Irrigation water savings per capita, induced by cool roofs, range from 1.8 to 15.4 gallons per day across 18 counties examined. Total water savings in Los Angeles county alone is about 83 million gallons per day. While this effect is robust across the 15 years examined (2001-2015), including both drought and non-drought years, we find that cool roofs are most effective during the hottest days of the year, indicating that they could play an even greater role in reducing outdoor water use in a hotter future climate. We further show that this synergistic relationship between heat mitigation and water conservation is asymmetrical - policies that encourage direct reductions in irrigation water use can lead to substantial regional warming, potentially conflicting with heat mitigation efforts designed to counter the effects of the projected warming climate.

Coordinating Mitigation Strategies for Meeting In-Stream Flow Requirements in the Skagit River Basin, WA

NASA Astrophysics Data System (ADS)

Padowski, J.; Yang, Q.; Brady, M.; Jessup, E.; Yoder, J.

2016-12-01

In 2013, the Washington State Supreme Court ruled against a 2001 amendment that set aside groundwater reservations for development within the Skagit River Basin (Swinomish Indian Tribal Community v. Washington State Department of Ecology). As a consequence, hundreds of properties no longer have a secure, uninterruptible water right and must be fully mitigated to offset their impacts on minimum in-stream flows. To date, no solutions have been amenable to the private, tribal and government parties involved. The objective of this study is to identify implementable, alternative water mitigation strategies for meeting minimum in-stream flow requirements while providing non-interruptible water to 455 property owners without legal water rights in the Skagit Basin. Three strategies of interest to all parties involved were considered: 1) streamflow augmentation from small-gauge municipal pipes, or trucked water deliveries for either 2) direct household use or 3) streamflow augmentation. Each mitigation strategy was assessed under two different demand scenarios and five augmentation points along 19 sub-watershed (HUC12) stream reaches. Results indicate that water piped for streamflow augmentation could provide mitigation at a cost of <10,000 per household for 20 - 60% of the properties in question, but a similar approach could be up to twenty times more expensive for those remaining properties in basins furthest from existing municipal systems. Trucked water costs also increase for upper basin properties, but over a 20-year period are still less expensive for basins where piped water costs would be high (e.g., 100,000 for trucking vs. $200,000 for piped water). This work suggests that coordination with municipal water systems to offset in-stream flow reductions, in combination with strategic mobile water delivery, could provide mitigation solutions within the Skagit Basin that may satisfy concerned parties.

LAND USE AS A MITIGATION STRATEGY FOR THE WATER QUALITY IMPACTS OF GLOBAL WARMING: A SCENARIO ANALYSIS ON TWO WATERSHEDS IN THE OHIO RIVER BASIN

EPA Science Inventory

This study uses an integrative approach to study the water quality impacts of future global climate and land use changes. In this study, changing land use types were used as a mitigation strategy to reduce the adverse impacts of global climate change on water resources. The Thorn...

Afghan National Police Training Program: Lessons Learned During the Transition of Contract Administration

DTIC Science & Technology

2011-08-15

coordinated transition requirements; • identifying and completing inherently governmental tasks; • conducting risk assessments and developing risk ...conducted risk assessments and developed risk mitigation strategies, defined metrics, and established a council of senior officials to oversee and... assessment to identify sources of risk that may affect the transition, and mitigation strategies to address those risks , which could help minimize the

LAND USE AS A MITIGATION STRATEGY FOR THE WATER QUALITY IMPACTS OF GLOBAL WARMING: A SCENARIO ANALYSIS ON TWO WATERSHEDS IN THE OHIO RIVER BASIN

EPA Science Inventory

This study uses an integrative approach to study the water quality impacts of future global climate and land use changes. In this study, changing land use types was used as a mitigation strategy to reduce the adverse impacts of global climate change on water resources. The climat...

Young and older adults' beliefs about effective ways to mitigate age-related memory decline.

PubMed

Horhota, Michelle; Lineweaver, Tara; Ositelu, Monique; Summers, Kristi; Hertzog, Christopher

2012-06-01

This study investigated whether young and older adults vary in their beliefs about the impact of various mitigating factors on age-related memory decline. Eighty young (ages 18-23) and 80 older (ages 60-82) participants reported their beliefs about their own memory abilities and the strategies that they use in their everyday lives to attempt to control their memory. Participants also reported their beliefs about memory change with age for hypothetical target individuals who were described as using (or not using) various means to mitigate memory decline. There were no age differences in personal beliefs about control over current or future memory ability. However, the two age groups differed in the types of strategies they used in their everyday life to control their memory. Young adults were more likely to use internal memory strategies, whereas older adults were more likely to focus on cognitive exercise and maintaining physical health as ways to optimize their memory ability. There were no age differences in rated memory change across the life span in hypothetical individuals. Both young and older adults perceived strategies related to improving physical and cognitive health as effective means of mitigating memory loss with age, whereas internal memory strategies were perceived as less effective means for controlling age-related memory decline. PsycINFO Database Record (c) 2012 APA, all rights reserved

California Dept. of Toxic Substances Control (DTSC) Update of the Schools Naturally Occurring Asbestos Guidance

NASA Astrophysics Data System (ADS)

Malinowski, M.

2012-12-01

Prior to acquisition and/or construction of prospective school sites, the California Education Code mandates that school districts complete environmental assessments and cleanups for prospective new or expanding school sites in order to qualify for state funding. If prospective school sites are determined to have environmental contamination from hazardous materials, including naturally occurring hazardous materials such as naturally occurring asbestos (NOA), where there may be unacceptable potential health risks, the school sites must be properly mitigated prior to occupancy for protection of human health and the environment. NOA is of special concern for schools, because children who are exposed to asbestos may be at increased risk of developing asbestos-related diseases over time. In order to protect human health, the Department of Toxic Substances Control's (DTSC) goals at school sites are to: 1) identify the presence of NOA in school site soils using exposure-reducing soil thresholds; 2) manage potential NOA exposures using mitigation measures to reduce generation of airborne asbestos fibers from soils on school sites; and 3) ensure long-term monitoring and protection of mitigation measures via Operations & Maintenance activities. DTSC is currently in the process of revising its Interim Guidance Naturally Occurring Asbestos (NOA) at School Sites - September 2004. The revisions include: 1) updating the guidance to consider incremental sampling for use at NOA sites in consultation with DTSC's project manager and technical staff, and 2) documenting a tiered approach to addressing high and low activity areas on a school.

GSD Update: Ushering in a new age of genetics to restore lands and conserve species

Treesearch

Deborah M. Finch

2013-01-01

Plant genetic information provides critical knowledge necessary to mitigate the impacts of climate change through ecological restoration. The first step in restoration is recognizing and delineating genetic boundaries at different taxonomic and spatial hierarchies (e.g., species, subspecies and populations). The second step is an assessment of the genetic diversity...

77 FR 34453 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-11

...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate Effectiveness of a Proposed Rule Change To Update the NASDAQ Options Market Message Traffic Mitigation Rule June 5, 2012...\\ thereunder, notice is hereby given that, on May 29, 2012, The NASDAQ Stock Market LLC (``NASDAQ'') filed with...

Wireless rake-receiver using adaptive filter with a family of partial update algorithms in noise cancellation applications

NASA Astrophysics Data System (ADS)

Fayadh, Rashid A.; Malek, F.; Fadhil, Hilal A.; Aldhaibani, Jaafar A.; Salman, M. K.; Abdullah, Farah Salwani

2015-05-01

For high data rate propagation in wireless ultra-wideband (UWB) communication systems, the inter-symbol interference (ISI), multiple-access interference (MAI), and multiple-users interference (MUI) are influencing the performance of the wireless systems. In this paper, the rake-receiver was presented with the spread signal by direct sequence spread spectrum (DS-SS) technique. The adaptive rake-receiver structure was shown with adjusting the receiver tap weights using least mean squares (LMS), normalized least mean squares (NLMS), and affine projection algorithms (APA) to support the weak signals by noise cancellation and mitigate the interferences. To minimize the data convergence speed and to reduce the computational complexity by the previous algorithms, a well-known approach of partial-updates (PU) adaptive filters were employed with algorithms, such as sequential-partial, periodic-partial, M-max-partial, and selective-partial updates (SPU) in the proposed system. The simulation results of bit error rate (BER) versus signal-to-noise ratio (SNR) are illustrated to show the performance of partial-update algorithms that have nearly comparable performance with the full update adaptive filters. Furthermore, the SPU-partial has closed performance to the full-NLMS and full-APA while the M-max-partial has closed performance to the full-LMS updates algorithms.

Impact of greenhouse gas metrics on the quantification of agricultural emissions and farm-scale mitigation strategies: a New Zealand case study

NASA Astrophysics Data System (ADS)

Reisinger, Andy; Ledgard, Stewart

2013-06-01

Agriculture emits a range of greenhouse gases. Greenhouse gas metrics allow emissions of different gases to be reported in a common unit called CO2-equivalent. This enables comparisons of the efficiency of different farms and production systems and of alternative mitigation strategies across all gases. The standard metric is the 100 year global warming potential (GWP), but alternative metrics have been proposed and could result in very different CO2-equivalent emissions, particularly for CH4. While significant effort has been made to reduce uncertainties in emissions estimates of individual gases, little effort has been spent on evaluating the implications of alternative metrics on overall agricultural emissions profiles and mitigation strategies. Here we assess, for a selection of New Zealand dairy farms, the effect of two alternative metrics (100 yr GWP and global temperature change potentials, GTP) on farm-scale emissions and apparent efficiency and cost effectiveness of alternative mitigation strategies. We find that alternative metrics significantly change the balance between CH4 and N2O; in some cases, alternative metrics even determine whether a specific management option would reduce or increase net farm-level emissions or emissions intensity. However, the relative ranking of different farms by profitability or emissions intensity, and the ranking of the most cost-effective mitigation options for each farm, are relatively unaffected by the metric. We conclude that alternative metrics would change the perceived significance of individual gases from agriculture and the overall cost to farmers if a price were applied to agricultural emissions, but the economically most effective response strategies are unaffected by the choice of metric.

The role of meat in strategies to achieve a sustainable diet lower in greenhouse gas emissions: A review.

PubMed

Hyland, John J; Henchion, Maeve; McCarthy, Mary; McCarthy, Sinéad N

2017-10-01

Food consumption is responsible for a considerable proportion of greenhouse gas emissions (GHGE). Hence, individual food choices have the potential to substantially influence both public health and the environment. Meat and animal products are relatively high in GHGE and therefore targeted in efforts to reduce dietary emissions. This review first highlights the complexities regarding sustainability in terms of meat consumption and thereafter discusses possible strategies that could be implemented to mitigate its climatic impact. It outlines how sustainable diets are possible without the elimination of meat. For instance, overconsumption of food in general, beyond our nutritional requirements, was found to be a significant contributor of emissions. Non-voluntary and voluntary mitigation strategies offer potential to reduce dietary GHGE. All mitigation strategies require careful consideration but on-farm sustainable intensification perhaps offers the most promise. However, a balance between supply and demand approaches is encouraged. Health should remain the overarching principle for policies and strategies concerned with shifting consumer behaviour towards sustainable diets. Copyright © 2017. Published by Elsevier Ltd.

A mixed-methods study of health worker migration from Jamaica.

PubMed

Tomblin Murphy, Gail; MacKenzie, Adrian; Waysome, Benjamin; Guy-Walker, Joan; Palmer, Rowena; Elliott Rose, Annette; Rigby, Janet; Labonté, Ronald; Bourgeault, Ivy Lynn

2016-06-30

This study sought to better understand the drivers of migration, its consequences, and the various strategies countries have employed to mitigate its negative impacts. The study was conducted in four countries-Jamaica, India, the Philippines, and South Africa-that have historically been 'sources' of health workers migrating to other countries. The aim of this paper is to present the findings from the Jamaica portion of the study. Data were collected using surveys of Jamaica's generalist and specialist physicians, nurses, midwives, and dental auxiliaries, as well as structured interviews with key informants representing government ministries, professional associations, regional health authorities, healthcare facilities, and educational institutions. Quantitative data were analyzed using descriptive statistics and regression models. Qualitative data were analyzed thematically. Multiple stakeholder engagement workshops were held across Jamaica to share and validate the study findings and discuss implications for the country. Migration of health workers from Jamaica continues to be prevalent. Its causes are numerous, long-standing, and systemic, and are largely based around differences in living and working conditions between Jamaica and 'destination' countries. There is minimal formal tracking of health worker migration from Jamaica, making scientific analysis of its consequences difficult. Although there is evidence of numerous national and international efforts to manage and mitigate the negative impacts of migration, there is little evidence of the implementation or effectiveness of such efforts. Potential additional strategies for better managing the migration of Jamaica's health workers include the use of information systems to formally monitor migration, updating the national cadre system for employment of health personnel, ensuring existing personnel management policies, such as bonding, are both clearly understood and equitably enforced, and providing greater formal and informal recognition of health personnel. Although historically common, migration of Jamaica's health workers is poorly monitored and understood. Improved management of the migration of Jamaica's health workers requires collaboration from stakeholders across multiple sectors. Indeed, participating stakeholders identified a wide range of potential strategies to better manage migration of Jamaica's health workers, the implementation and testing of which will have potential benefits to Jamaica as well as other 'source' countries.

Coast Guard: Strategies for Mitigating the Loss of Patrol Boats Are Achieving Results in the Near Term, but They Come at a Cost and Longer Term Sustainability Is Unknown

DTIC Science & Technology

2008-06-01

Committee on Commerce, Science, and Transportation, U.S. Senate The Coast Guard’s 110-foot patrol boats are used for a number of missions, such as...implemented a number of strategies. These mitigation strategies nclude: using the crews from the eight patrol boats removed from service to ugment...55 Page i GAO-08-660 Coast Guard Tables Table 1: Information on the Vessel Classes Used to Provide Operational Hours in

Nurses' Perceptions of Implementing Fall Prevention Interventions to Mitigate Patient-Specific Fall Risk Factors.

PubMed

Wilson, Deleise S; Montie, Mary; Conlon, Paul; Reynolds, Margaret; Ripley, Robert; Titler, Marita G

2016-08-01

Evidence-based (EB) fall prevention interventions to mitigate patient-specific fall risk factors are readily available but not routinely used in practice. Few studies have examined nurses' perceptions about both the use of these EB interventions and implementation strategies designed to promote their adoption. This article reports qualitative findings of nurses' perceptions about use of EB fall prevention interventions to mitigate patient-specific fall risks, and implementation strategies to promote use of these interventions. The findings revealed five major themes: before-study fall prevention practices, use of EB fall prevention interventions tailored to patient-specific fall risk factors, beneficial implementation strategies, overall impact on approach to fall prevention, and challenges These findings are useful to guide nurses' engagement and use of EB fall prevention practices tailored to patient-specific fall risk factors. © The Author(s) 2016.

Scalable and fail-safe deployment of the ATLAS Distributed Data Management system Rucio

NASA Astrophysics Data System (ADS)

Lassnig, M.; Vigne, R.; Beermann, T.; Barisits, M.; Garonne, V.; Serfon, C.

2015-12-01

This contribution details the deployment of Rucio, the ATLAS Distributed Data Management system. The main complication is that Rucio interacts with a wide variety of external services, and connects globally distributed data centres under different technological and administrative control, at an unprecedented data volume. It is therefore not possible to create a duplicate instance of Rucio for testing or integration. Every software upgrade or configuration change is thus potentially disruptive and requires fail-safe software and automatic error recovery. Rucio uses a three-layer scaling and mitigation strategy based on quasi-realtime monitoring. This strategy mainly employs independent stateless services, automatic failover, and service migration. The technologies used for deployment and mitigation include OpenStack, Puppet, Graphite, HAProxy and Apache. In this contribution, the interplay between these components, their deployment, software mitigation, and the monitoring strategy are discussed.

The Urban Heat Island Phenomenon and Potential Mitigation Strategies

NASA Technical Reports Server (NTRS)

Estes, Maurice G., Jr.; Gorsevski, Virginia; Russell, Camille; Quattrochi, Dale; Luvall, Jeffrey

1999-01-01

A survey of urban heat island research is provided to describe how heat islands develop, urban landscape and meteorological characteristics that facilitate development, use of aircraft remote sensing data, and why heat islands are of interest to planners, elected officials, and the public. The roles of the National Aeronautics and Space Administration (NASA), the Environmental Protection Agency (EPA), other federal agencies, national laboratories and universities, state and local governments, and non-governmental organizations (NGOS) in studying the urban heat island effect and developing mitigation strategies are explored. Barriers that hamper mitigation efforts and case studies in Atlanta and Salt Lake City are discussed.

Mitigation: Decarbonization unique to cities

NASA Astrophysics Data System (ADS)

Ibrahim, Nadine

2017-10-01

Strategies that reduce fossil-fuel use can achieve both global carbon mitigation and local health-protection goals. Now research shows the dual benefits of compact urban design and circular economy policies in Chinese cities.

Drug Target Interference in Immunogenicity Assays: Recommendations and Mitigation Strategies.

PubMed

Zhong, Zhandong Don; Clements-Egan, Adrienne; Gorovits, Boris; Maia, Mauricio; Sumner, Giane; Theobald, Valerie; Wu, Yuling; Rajadhyaksha, Manoj

2017-11-01

Sensitive and specific methodology is required for the detection and characterization of anti-drug antibodies (ADAs). High-quality ADA data enables the evaluation of potential impact of ADAs on the drug pharmacokinetic profile, patient safety, and efficacious response to the drug. Immunogenicity assessments are typically initiated at early stages in preclinical studies and continue throughout the drug development program. One of the potential bioanalytical challenges encountered with ADA testing is the need to identify and mitigate the interference mediated by the presence of soluble drug target. A drug target, when present at sufficiently high circulating concentrations, can potentially interfere with the performance of ADA and neutralizing antibody (NAb) assays, leading to either false-positive or, in some cases, false-negative ADA and NAb assay results. This publication describes various mechanisms of assay interference by soluble drug target, as well as strategies to recognize and mitigate such target interference. Pertinent examples are presented to illustrate the impact of target interference on ADA and NAb assays as well as several mitigation strategies, including the use of anti-target antibodies, soluble versions of the receptors, target-binding proteins, lectins, and solid-phase removal of targets. Furthermore, recommendations for detection and mitigation of such interference in different formats of ADA and NAb assays are provided.

Status Report on Modelling and Simulation Capabilities for Nuclear-Renewable Hybrid Energy Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rabiti, C.; Epiney, A.; Talbot, P.

This report summarizes the current status of the modeling and simulation capabilities developed for the economic assessment of Nuclear-Renewable Hybrid Energy Systems (N-R HES). The increasing penetration of variable renewables is altering the profile of the net demand, with which the other generators on the grid have to cope. N-R HES analyses are being conducted to determine the potential feasibility of mitigating the resultant volatility in the net electricity demand by adding industrial processes that utilize either thermal or electrical energy as stabilizing loads. This coordination of energy generators and users is proposed to mitigate the increase in electricity costmore » and cost volatility through the production of a saleable commodity. Overall, the financial performance of a system that is comprised of peaking units (i.e. gas turbine), baseload supply (i.e. nuclear power plant), and an industrial process (e.g. hydrogen plant) should be optimized under the constraint of satisfying an electricity demand profile with a certain level of variable renewable (wind) penetration. The optimization should entail both the sizing of the components/subsystems that comprise the system and the optimal dispatch strategy (output at any given moment in time from the different subsystems). Some of the capabilities here described have been reported separately in [1, 2, 3]. The purpose of this report is to provide an update on the improvement and extension of those capabilities and to illustrate their integrated application in the economic assessment of N-R HES.« less

Economic evaluation of influenza pandemic mitigation strategies in the us using a stochastic microsimulation transmission model

PubMed Central

Sander, Beate; Nizam, Azhar; Garrison, Louis P.; Postma, Maarten J.; Halloran, M. Elizabeth; Longini, Ira M.

2013-01-01

Objectives To project the potential economic impact of pandemic influenza mitigation strategies from a societal perspective in the United States. Methods We use a stochastic agent-based model to simulate pandemic influenza in the community. We compare 17 strategies: targeted antiviral prophylaxis (TAP) alone and in combination with school closure as well as prevaccination. Results In the absence of intervention, we predict a 50% attack rate with an economic impact of $187 per capita as loss to society. Full TAP is the most effective single strategy, reducing number of cases by 54% at the lowest cost to society ($127 per capita). Prevaccination reduces number of cases by 48% and is the second least costly alternative ($140 per capita). Adding school closure to full TAP or prevaccination further improves health outcomes, but increases total cost to society by approximately $2700 per capita. Conclusion Full targeted antiviral prophylaxis is an effective and cost-saving measure for mitigating pandemic influenza. PMID:18671770

Implementing climate change mitigation in health services: the importance of context.

PubMed

Desmond, Sharon

2016-10-01

Academic interest in strategies to reduce the impact of health services on climate change is quickening. Research has largely focused on local innovations with little consideration of the contextual and systemic elements that influence sustainable development across health systems. A realistic framework specifically to guide decision-making by health care providers is still needed. To address this deficit, the literature is explored in relation to health services and climate change mitigation strategies, and the contextual factors that influence efforts to mitigate climate effects in health service delivery environments are highlighted. A conceptual framework is proposed that offers a model for the pursuit of sustainable development practice in health services. A set of propositions is advanced to provide a systems approach to assist decision-making by decoding the challenges faced in implementing sustainable health services. This has important implications for health care providers, funders and legislators since the financial, policy and regulatory environment of health care, along with its leadership and models of care generally conflict with carbon literacy and climate change mitigation strategies. © The Author(s) 2016.

Performance analysis of a GPS equipment by general linear models approach

NASA Astrophysics Data System (ADS)

Teodoro, M. Filomena; Gonçalves, Fernando M.; Correia, Anacleto

2017-06-01

One of the major challenges in processing high-accurate long baselines is the presence of un-modelled ionospheric and tropospheric delays. There are effective mitigation strategies for ionospheric biases, such as the ionosphere-free linear combination of L1 and L2 carrier-phase, which can remove about 98% of the first-order ionospheric biases. With few exceptions this was the solution found by LGO for the 11760 baselines processed in this research. Therefore, for successful results, the appropriated approach to the mitigation of biases due to tropospheric delays is vital. The main aim of the investigations presented in this work was to evaluate the improvements, or not, of the rate of baselines successfully produced by adopting an advanced tropospheric bias mitigation strategy as opposed to a sample tropospheric bias mitigation approach. In both cases LGO uses as a priori tropospheric model the simplified Hopfield model, improved in the first case with a zenith tropospheric scale factor per station. Being aware that 1D and 2D present different behaviors, both cases are analyzed individually with each strategy.

Handbook on Coral Reef Impacts: Avoidance, Minimization, Compensatory Mitigation, and Restoration

EPA Pesticide Factsheets

This Handbook provides a general summary of current avoidance, minimization, compensatory mitigation, and restoration strategies that may help address physical damage resulting from direct adverse impacts to coral reefs.

Forest environmental investments and implications for climate change mitigation.

Treesearch

Ralph J. Alig; Lucas S. Bair

2006-01-01

Forest environmental conditions are affected by climate change, but investments in forest environmental quality can be used as part of the climate change mitigation strategy. A key question involving the potential use of forests to store more carbon as part of climate change mitigation is the impact of forest investments on the timing and quantity of forest volumes...

Sample size determination for bibliographic retrieval studies

PubMed Central

Yao, Xiaomei; Wilczynski, Nancy L; Walter, Stephen D; Haynes, R Brian

2008-01-01

Background Research for developing search strategies to retrieve high-quality clinical journal articles from MEDLINE is expensive and time-consuming. The objective of this study was to determine the minimal number of high-quality articles in a journal subset that would need to be hand-searched to update or create new MEDLINE search strategies for treatment, diagnosis, and prognosis studies. Methods The desired width of the 95% confidence intervals (W) for the lowest sensitivity among existing search strategies was used to calculate the number of high-quality articles needed to reliably update search strategies. New search strategies were derived in journal subsets formed by 2 approaches: random sampling of journals and top journals (having the most high-quality articles). The new strategies were tested in both the original large journal database and in a low-yielding journal (having few high-quality articles) subset. Results For treatment studies, if W was 10% or less for the lowest sensitivity among our existing search strategies, a subset of 15 randomly selected journals or 2 top journals were adequate for updating search strategies, based on each approach having at least 99 high-quality articles. The new strategies derived in 15 randomly selected journals or 2 top journals performed well in the original large journal database. Nevertheless, the new search strategies developed using the random sampling approach performed better than those developed using the top journal approach in a low-yielding journal subset. For studies of diagnosis and prognosis, no journal subset had enough high-quality articles to achieve the expected W (10%). Conclusion The approach of randomly sampling a small subset of journals that includes sufficient high-quality articles is an efficient way to update or create search strategies for high-quality articles on therapy in MEDLINE. The concentrations of diagnosis and prognosis articles are too low for this approach. PMID:18823538

Damage-mitigating control of aerospace systems for high performance and extended life

NASA Technical Reports Server (NTRS)

Ray, Asok; Wu, Min-Kuang; Carpino, Marc; Lorenzo, Carl F.; Merrill, Walter C.

1992-01-01

The concept of damage-mitigating control is to minimize fatigue (as well as creep and corrosion) damage of critical components of mechanical structures while simultaneously maximizing the system dynamic performance. Given a dynamic model of the plant and the specifications for performance and stability robustness, the task is to synthesize a control law that would meet the system requirements and, at the same time, satisfy the constraints that are imposed by the material and structural properties of the critical components. The authors present the concept of damage-mitigating control systems design with the following objectives: (1) to achieve high performance with a prolonged life span; and (2) to systematically update the controller as the new technology of advanced materials evolves. The major challenge is to extract the information from the material properties and then utilize this information in a mathematical form so that it can be directly applied to robust control synthesis for mechanical systems. The basic concept of damage-mitigating control is illustrated using a relatively simplified model of a space shuttle main engine.

A review of statistical updating methods for clinical prediction models.

PubMed

Su, Ting-Li; Jaki, Thomas; Hickey, Graeme L; Buchan, Iain; Sperrin, Matthew

2018-01-01

A clinical prediction model is a tool for predicting healthcare outcomes, usually within a specific population and context. A common approach is to develop a new clinical prediction model for each population and context; however, this wastes potentially useful historical information. A better approach is to update or incorporate the existing clinical prediction models already developed for use in similar contexts or populations. In addition, clinical prediction models commonly become miscalibrated over time, and need replacing or updating. In this article, we review a range of approaches for re-using and updating clinical prediction models; these fall in into three main categories: simple coefficient updating, combining multiple previous clinical prediction models in a meta-model and dynamic updating of models. We evaluated the performance (discrimination and calibration) of the different strategies using data on mortality following cardiac surgery in the United Kingdom: We found that no single strategy performed sufficiently well to be used to the exclusion of the others. In conclusion, useful tools exist for updating existing clinical prediction models to a new population or context, and these should be implemented rather than developing a new clinical prediction model from scratch, using a breadth of complementary statistical methods.

Testing the effectiveness of simplified search strategies for updating systematic reviews.

PubMed

Rice, Maureen; Ali, Muhammad Usman; Fitzpatrick-Lewis, Donna; Kenny, Meghan; Raina, Parminder; Sherifali, Diana

2017-08-01

The objective of the study was to test the overall effectiveness of a simplified search strategy (SSS) for updating systematic reviews. We identified nine systematic reviews undertaken by our research group for which both comprehensive and SSS updates were performed. Three relevant performance measures were estimated, that is, sensitivity, precision, and number needed to read (NNR). The update reference searches for all nine included systematic reviews identified a total of 55,099 citations that were screened resulting in final inclusion of 163 randomized controlled trials. As compared with reference search, the SSS resulted in 8,239 hits and had a median sensitivity of 83.3%, while precision and NNR were 4.5 times better. During analysis, we found that the SSS performed better for clinically focused topics, with a median sensitivity of 100% and precision and NNR 6 times better than for the reference searches. For broader topics, the sensitivity of the SSS was 80% while precision and NNR were 5.4 times better compared with reference search. SSS performed well for clinically focused topics and, with a median sensitivity of 100%, could be a viable alternative to a conventional comprehensive search strategy for updating this type of systematic reviews particularly considering the budget constraints and the volume of new literature being published. For broader topics, 80% sensitivity is likely to be considered too low for a systematic review update in most cases, although it might be acceptable if updating a scoping or rapid review. Copyright © 2017 Elsevier Inc. All rights reserved.

The Canadian critical care nutrition guidelines in 2013: an update on current recommendations and implementation strategies.

PubMed

Dhaliwal, Rupinder; Cahill, Naomi; Lemieux, Margot; Heyland, Daren K

2014-02-01

Clinical practice guidelines (CPGs) are systematically developed statements to assist practitioners and patient decisions about appropriate healthcare for specific clinical circumstances, and are designed to minimize practice variation, improve costs, and improve clinical outcomes. The Canadian Critical Care Practice Guidelines (CCPGs) were first published in 2003 and most recently updated in 2013. A total of 68 new randomized controlled trials were identified since the last version in 2009, 50 of them published between 2009 and 2013. The remaining articles were trials published before 2009 but were not identified in previous iterations of the CCPGs. For clinical practice guidelines to be useful to practitioners, they need to be up-to-date and be reflective of the current body of evidence. Herein we describe the process by which the CCPGs were updated. This process resulted in 10 new sections or clinical topics. Of the old clinical topics, 3 recommendations were upgraded, 4 were downgraded, and 27 remained the same. To influence decision making at the bedside, these updated guidelines need to be accompanied by active guideline implementation strategies. Optimal implementation strategies should be guided by local contextual factors including barriers and facilitators to best practice recommendations. Moreover, evaluating and monitoring performance, such as participating in the International Nutrition Survey of practice, should be part of any intensive care unit's performance improvement strategy. The active implementation of the updated CCPGs may lead to better nutrition care and improved patient outcomes in the critical care setting.

Mitigation Strategies for Greenhouse Gas Emissions from Agriculture and Land-Use Change: Consequences for Food Prices.

PubMed

Stevanović, Miodrag; Popp, Alexander; Bodirsky, Benjamin Leon; Humpenöder, Florian; Müller, Christoph; Weindl, Isabelle; Dietrich, Jan Philipp; Lotze-Campen, Hermann; Kreidenweis, Ulrich; Rolinski, Susanne; Biewald, Anne; Wang, Xiaoxi

2017-01-03

The land use sector of agriculture, forestry, and other land use (AFOLU) plays a central role in ambitious climate change mitigation efforts. Yet, mitigation policies in agriculture may be in conflict with food security related targets. Using a global agro-economic model, we analyze the impacts on food prices under mitigation policies targeting either incentives for producers (e.g., through taxes) or consumer preferences (e.g., through education programs). Despite having a similar reduction potential of 43-44% in 2100, the two types of policy instruments result in opposite outcomes for food prices. Incentive-based mitigation, such as protecting carbon-rich forests or adopting low-emission production techniques, increase land scarcity and production costs and thereby food prices. Preference-based mitigation, such as reduced household waste or lower consumption of animal-based products, decreases land scarcity, prevents emissions leakage, and concentrates production on the most productive sites and consequently lowers food prices. Whereas agricultural emissions are further abated in the combination of these mitigation measures, the synergy of strategies fails to substantially lower food prices. Additionally, we demonstrate that the efficiency of agricultural emission abatement is stable across a range of greenhouse-gas (GHG) tax levels, while resulting food prices exhibit a disproportionally larger spread.

Wanaket Wildlife Area Management Plan : Five-Year Plan for Protecting, Enhancing, and Mitigating Wildlife Habitat Losses for the McNary Hydroelectric Facility.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Confederated Tribes of the Umatilla Indian Reservation Wildlife Program

The Confederated Tribes of the Umatilla Indian Reservation (CTUIR) propose to continue to protect, enhance, and mitigate wildlife and wildlife habitat at the Wanaket Wildlife Area. The Wanaket Wildlife Area was approved as a Columbia River Basin Wildlife Mitigation Project by the Bonneville Power Administration (BPA) and Northwest Power Planning Council (NWPPC) in 1993. This management plan will provide an update of the original management plan approved by BPA in 1995. Wanaket will contribute towards meeting BPA's obligation to compensate for wildlife habitat losses resulting from the construction of the McNary Hydroelectric facility on the Columbia River. By funding themore » enhancement and operation and maintenance of the Wanaket Wildlife Area, BPA will receive credit towards their mitigation debt. The purpose of the Wanaket Wildlife Area management plan update is to provide programmatic and site-specific standards and guidelines on how the Wanaket Wildlife Area will be managed over the next five years. This plan provides overall guidance on both short and long term activities that will move the area towards the goals, objectives, and desired future conditions for the planning area. The plan will incorporate managed and protected wildlife and wildlife habitat, including operations and maintenance, enhancements, and access and travel management. Specific project objectives are related to protection and enhancement of wildlife habitats and are expressed in terms of habitat units (HU's). Habitat units were developed by the US Fish and Wildlife Service's Habitat Evaluation Procedures (HEP), and are designed to track habitat gains and/or losses associated with mitigation and/or development projects. Habitat Units for a given species are a product of habitat quantity (expressed in acres) and habitat quality estimates. Habitat quality estimates are developed using Habitat Suitability Indices (HSI). These indices are based on quantifiable habitat features such as vegetation height, shrub cover, or other parameters, which are known to provide life history requisites for mitigation species. Habitat Suitability Indices range from 0 to 1, with an HSI of 1 providing optimum habitat conditions for the selected species. One acre of optimum habitat provides one Habitat Unit. The objective of continued management of the Wanaket Wildlife Mitigation Area, including protection and enhancement of upland and wetland/wetland associated cover types, is to provide and maintain 2,334 HU's of protection credit and generate 2,495 HU's of enhancement credit by the year 2004.« less

Anticipation and response: pandemic influenza in Malawi, 2009

PubMed Central

Sambala, Evanson Z.; Manderson, Lenore

2017-01-01

ABSTRACT Background: In 2006, Malawi developed a national influenza plan to mitigate, prevent and manage the burden of infection should an outbreak occur. In 2009, it translated its contingency plan to respond to the unfolding influenza pandemic. However, little is known of how Malawi translated its national influenza plan into response actions, or the success of these responses. Objective: To investigate how Malawi translated its preparedness plan and so broaden our understanding of the outcomes of the responses. Methods: We draw on data from 22 in-depth interviews with government policymakers and people working at a policy level in various non-governmental organisations, conducted to assess the level of preparedness and the challenges of translating this. Results: Through a number of public health initiatives, authorities developed communication strategies, strengthened influenza surveillance activities and updated overall goals in pandemic training and education. However, without influenza drills, exercises and simulations to test the plan, activating the pandemic plan, including coordinating and deploying generic infection control measures, was problematic. Responses during the pandemic were at times ‘weak and clumsy’ and failed to mirror the activities and processes highlighted in the preparedness plan. Conclusions: Participants stressed that in order to achieve a coordinated and successful response to mitigate and prevent the further transmission of pandemic influenza, good preparation was critical. The key elements which they identified as relevant for a rapid response included effective communications, robust evidence-based decision-making, strong and reliable surveillance systems and flexible public health responses. To effectively articulate a viable trajectory of pandemic responses, the potential value of simulation exercises could be given more consideration as a mean of sustaining good levels of preparedness and responses against future pandemics. These all demand a well-structured planning for and response to pandemic influenza strategy developed by a functioning scientific and policy advisory committee. PMID:28753109

Soil mapping and processes models to support climate change mitigation and adaptation strategies: a review

NASA Astrophysics Data System (ADS)

Muñoz-Rojas, Miriam; Pereira, Paulo; Brevik, Eric; Cerda, Artemi; Jordan, Antonio

2017-04-01

As agreed in Paris in December 2015, global average temperature is to be limited to "well below 2 °C above pre-industrial levels" and efforts will be made to "limit the temperature increase to 1.5 °C above pre-industrial levels. Thus, reducing greenhouse gas emissions (GHG) in all sectors becomes critical and appropriate sustainable land management practices need to be taken (Pereira et al., 2017). Mitigation strategies focus on reducing the rate and magnitude of climate change by reducing its causes. Complementary to mitigation, adaptation strategies aim to minimise impacts and maximize the benefits of new opportunities. The adoption of both practices will require developing system models to integrate and extrapolate anticipated climate changes such as global climate models (GCMs) and regional climate models (RCMs). Furthermore, integrating climate models driven by socio-economic scenarios in soil process models has allowed the investigation of potential changes and threats in soil characteristics and functions in future climate scenarios. One of the options with largest potential for climate change mitigation is sequestering carbon in soils. Therefore, the development of new methods and the use of existing tools for soil carbon monitoring and accounting have therefore become critical in a global change context. For example, soil C maps can help identify potential areas where management practices that promote C sequestration will be productive and guide the formulation of policies for climate change mitigation and adaptation strategies. Despite extensive efforts to compile soil information and map soil C, many uncertainties remain in the determination of soil C stocks, and the reliability of these estimates depends upon the quality and resolution of the spatial datasets used for its calculation. Thus, better estimates of soil C pools and dynamics are needed to advance understanding of the C balance and the potential of soils for climate change mitigation. Here, we discuss the most recent advances on the application of soil mapping and modeling to support climate change mitigation and adaptation strategies; and These strategies are a key component of the implementation of sustainable land management policies need to be integrated are critical to. The objective of this work is to present a review about the advantages of soil mapping and process modeling for sustainable land management. Muñoz-Rojas, M., Pereira, P., Brevic, E., Cerda, A., Jordan, A. (2017) Soil mapping and processes models for sustainable land management applied to modern challenges. In: Pereira, P., Brevik, E., Munoz-Rojas, M., Miller, B. (Eds.) Soil mapping and process modelling for sustainable land use management (Elsevier Publishing House) ISBN: 9780128052006

Interagency Report on Orbital Debris, 1995

NASA Technical Reports Server (NTRS)

1995-01-01

This 1995 report updates the findings and recommendations of the 1989 report and reflects the authors' progress in understanding and managing the orbital debris environment. It provides an up-to-date portrait of their measurement, modeling, and mitigation efforts; and a set of recommendations outlining specific steps they should pursue, both domestically and internationally, to minimize the potential hazard posed by orbital debris.

Steam generator degradation: Current mitigation strategies for controlling corrosion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Millett, P.

1997-02-01

Steam Generator degradation has caused substantial losses of power generation, resulted in large repair and maintenance costs, and contributed to significant personnel radiation exposures in Pressurized Water Reactors (PWRs) operating throughout the world. EPRI has just published the revised Steam Generator Reference Book, which reviews all of the major forms of SG degradation. This paper discusses the types of SG degradation that have been experienced with emphasis on the mitigation strategies that have been developed and implemented in the field. SG degradation is presented from a world wide perspective as all countries operating PWRs have been effected to one degreemore » or another. The paper is written from a US. perspective where the utility industry is currently undergoing tremendous change as a result of deregulation of the electricity marketplace. Competitive pressures are causing utilities to strive to reduce Operations and Maintenance (O&M) and capital costs. SG corrosion is a major contributor to the O&M costs of PWR plants, and therefore US utilities are evaluating and implementing the most cost effective solutions to their corrosion problems. Mitigation strategies developed over the past few years reflect a trend towards plant specific solutions to SG corrosion problems. Since SG degradation is in most cases an economic problem and not a safety problem, utilities can focus their mitigation strategies on their unique financial situation. Accordingly, the focus of R&D has shifted from the development of more expensive, prescriptive solutions (e.g. reduced impurity limits) to corrosion problems to providing the utilities with a number of cost effective mitigation options (e.g. molar ratio control, boric acid treatment).« less

Evolution of cooperation driven by incremental learning

NASA Astrophysics Data System (ADS)

Li, Pei; Duan, Haibin

2015-02-01

It has been shown that the details of microscopic rules in structured populations can have a crucial impact on the ultimate outcome in evolutionary games. So alternative formulations of strategies and their revision processes exploring how strategies are actually adopted and spread within the interaction network need to be studied. In the present work, we formulate the strategy update rule as an incremental learning process, wherein knowledge is refreshed according to one's own experience learned from the past (self-learning) and that gained from social interaction (social-learning). More precisely, we propose a continuous version of strategy update rules, by introducing the willingness to cooperate W, to better capture the flexibility of decision making behavior. Importantly, the newly gained knowledge including self-learning and social learning is weighted by the parameter ω, establishing a strategy update rule involving innovative element. Moreover, we quantify the macroscopic features of the emerging patterns to inspect the underlying mechanisms of the evolutionary process using six cluster characteristics. In order to further support our results, we examine the time evolution course for these characteristics. Our results might provide insights for understanding cooperative behaviors and have several important implications for understanding how individuals adjust their strategies under real-life conditions.

Design of Firmware Update Strategy in Tower Mounted Amplifier

NASA Astrophysics Data System (ADS)

Lv, Yi; Han, Shuqin

With rapid development of radio communication, Tower mounted amplifier (TMA) that conform to AISG protocol will be increasingly applied. Remote firmware update function is essential for TMA. In this paper, a method about remote firmware update that conforms to AISG2.0 is proposed. In this paper, defect of traditional firmware storage is given, and the implementation procedure of firmware storing that based on internal flash of STR755 was introduced. According to corresponding specification in aisg2.0, the process of firmware download and activation are provided in detail. The key point of bootloader was given. Application result shows that the strategy is reliable and highly secure.

Mitigating amphibian disease: strategies to maintain wild populations and control chytridiomycosis

USGS Publications Warehouse

Woodhams, Douglas C.; Bosch, Jaime; Briggs, Cheryl J.; Cashins, Scott; Davis, Leyla R.; Lauer, Antje; Muths, Erin L.; Puschendorf, Robert; Schmidt, Benedikt R.; Sheafor, Brandon; Voyles, Jamie

2011-01-01

Because sustainable conservation of amphibians in nature is dependent on long-term population persistence and co-evolution with potentially lethal pathogens, we suggest that disease mitigation not focus exclusively on the elimination or containment of the pathogen, or on the captive breeding of amphibian hosts. Rather, successful disease mitigation must be context specific with epidemiologically informed strategies to manage already infected populations by decreasing pathogenicity and host susceptibility. We propose population level treatments based on three steps: first, identify mechanisms of disease suppression; second, parameterize epizootiological models of disease and population dynamics for testing under semi-natural conditions; and third, begin a process of adaptive management in field trials with natural populations.

Mining moving object trajectories in location-based services for spatio-temporal database update

NASA Astrophysics Data System (ADS)

Guo, Danhuai; Cui, Weihong

2008-10-01

Advances in wireless transmission and mobile technology applied to LBS (Location-based Services) flood us with amounts of moving objects data. Vast amounts of gathered data from position sensors of mobile phones, PDAs, or vehicles hide interesting and valuable knowledge and describe the behavior of moving objects. The correlation between temporal moving patterns of moving objects and geo-feature spatio-temporal attribute was ignored, and the value of spatio-temporal trajectory data was not fully exploited too. Urban expanding or frequent town plan change bring about a large amount of outdated or imprecise data in spatial database of LBS, and they cannot be updated timely and efficiently by manual processing. In this paper we introduce a data mining approach to movement pattern extraction of moving objects, build a model to describe the relationship between movement patterns of LBS mobile objects and their environment, and put up with a spatio-temporal database update strategy in LBS database based on trajectories spatiotemporal mining. Experimental evaluation reveals excellent performance of the proposed model and strategy. Our original contribution include formulation of model of interaction between trajectory and its environment, design of spatio-temporal database update strategy based on moving objects data mining, and the experimental application of spatio-temporal database update by mining moving objects trajectories.

Mission design considerations for nuclear risk mitigation

NASA Technical Reports Server (NTRS)

Stancati, Mike; Collins, John

1993-01-01

Strategies for the mitigation of the nuclear risk associated with two specific mission operations are discussed. These operations are the safe return of nuclear thermal propulsion reactors to earth orbit and the disposal of lunar/Mars spacecraft reactors.

Identifying, anticipating, and mitigating freight bottlenecks on Alabama interstates.

DOT National Transportation Integrated Search

2011-07-31

"This project established a framework for the creation and maintenance of a statewide strategy for identifying, : anticipating, and mitigating freight bottlenecks on interstate highways in the state of Alabama. It used : methodology developed by Camb...

Co-Optima Highlights Primary Causes of Misfueling and Mitigation Strategies

Science.gov Websites

% ethanol; 90% unleaded gasoline) for use in any gasoline vehicle. Many misfueling mitigation measures such lead to vehicle systems damage. Measures such as nozzle colors are not universally standardized. Fuel

Land use and management change under climate change adaptation and mitigation strategies: a U.S. case study

USGS Publications Warehouse

Mu, Jianhong E.; Wein, Anne; McCarl, Bruce

2015-01-01

We examine the effects of crop management adaptation and climate mitigation strategies on land use and land management, plus on related environmental and economic outcomes. We find that crop management adaptation (e.g. crop mix, new species) increases Greenhouse gas (GHG) emissions by 1.7 % under a more severe climate projection while a carbon price reduces total forest and agriculture GHG annual flux by 15 % and 9 %, respectively. This shows that trade-offs are likely between mitigation and adaptation. Climate change coupled with crop management adaptation has small and mostly negative effects on welfare; mitigation, which is implemented as a carbon price starting at $15 per metric ton carbon dioxide (CO2) equivalent with a 5 % annual increase rate, bolsters welfare carbon payments. When both crop management adaptation and carbon price are implemented the effects of the latter dominates.

Signal timing under saturated conditions.

DOT National Transportation Integrated Search

2008-11-01

This report provides guidance to practitioners on effective strategies to mitigate the effects of congestion at signalized intersections. The scope is limited to single intersections and does not address network-level strategies. The strategies are d...

Effects of Title IV of the Clean Air Act Amendments of 1990 on Electric Utilities: An Update, The

EIA Publications

1997-01-01

Describes the strategies used to comply with the Acid Rain Program in 1995, the effect of compliance on SO2 emissions levels, the cost of compliance, and the effects of the program on coal supply and demand. It updates and expands the EIA report, Electric Utility Phase I Acid Rain Compliance Strategies for the Clean Air Act Amendments of 1990.

Adaptation of clinical prediction models for application in local settings.

PubMed

Kappen, Teus H; Vergouwe, Yvonne; van Klei, Wilton A; van Wolfswinkel, Leo; Kalkman, Cor J; Moons, Karel G M

2012-01-01

When planning to use a validated prediction model in new patients, adequate performance is not guaranteed. For example, changes in clinical practice over time or a different case mix than the original validation population may result in inaccurate risk predictions. To demonstrate how clinical information can direct updating a prediction model and development of a strategy for handling missing predictor values in clinical practice. A previously derived and validated prediction model for postoperative nausea and vomiting was updated using a data set of 1847 patients. The update consisted of 1) changing the definition of an existing predictor, 2) reestimating the regression coefficient of a predictor, and 3) adding a new predictor to the model. The updated model was then validated in a new series of 3822 patients. Furthermore, several imputation models were considered to handle real-time missing values, so that possible missing predictor values could be anticipated during actual model use. Differences in clinical practice between our local population and the original derivation population guided the update strategy of the prediction model. The predictive accuracy of the updated model was better (c statistic, 0.68; calibration slope, 1.0) than the original model (c statistic, 0.62; calibration slope, 0.57). Inclusion of logistical variables in the imputation models, besides observed patient characteristics, contributed to a strategy to deal with missing predictor values at the time of risk calculation. Extensive knowledge of local, clinical processes provides crucial information to guide the process of adapting a prediction model to new clinical practices.

An economic model to evaluate the mitigation programme for bovine viral diarrhoea in Switzerland.

PubMed

Häsler, B; Howe, K S; Presi, P; Stärk, K D C

2012-09-15

Economic analyses are indispensable as sources of information to help policy makers make decisions about mitigation resource use. The aim of this study was to conduct an economic evaluation of the Swiss national mitigation programme for bovine viral diarrhoea virus (BVDV), which was implemented in 2008 and concludes in 2017. The eradication phase of the mitigation programme comprised testing and slaughtering of all persistently infected (PI) animals found. First, the whole population was antigen tested and all PI cattle removed. Since October 2008, all newborn calves have been subject to antigen testing to identify and slaughter PI calves. All mothers of PI calves were retested and slaughtered if the test was positive. Antigen testing in calves and elimination of virus-carriers was envisaged to be conducted until the end of 2011. Subsequently, a surveillance programme will document disease freedom or detect disease if it recurs. Four alternative surveillance strategies based on antibody testing in blood from newborn calves and/or milk from primiparous cows were proposed by Federal Veterinary Office servants in charge of the BVDV mitigation programme. A simple economic spreadsheet model was developed to estimate and compare the costs and benefits of the BVDV mitigation programme. In an independent project, the impact of the mitigation programme on the disease dynamics in the population was simulated using a stochastic compartment model. Mitigation costs accrued from materials, labour, and processes such as handling and testing samples, and recording results. Benefits were disease costs avoided by having the mitigation programme in place compared to a baseline of endemic disease equilibrium. Cumulative eradication costs and benefits were estimated to determine the break-even point for the eradication component of the programme. The margin over eradication cost therefore equalled the maximum expenditure potentially available for surveillance without the net benefit from the mitigation programme overall becoming zero. Costs of the four surveillance strategies and the net benefit of the mitigation programme were estimated. Simulations were run for the years 2008-2017 with 20,000 iterations in @Risk for Excel. The mean baseline disease costs were estimated to be 16.04 m CHF (1 Swiss Franc, CHF=0.73 € at the time of analysis) (90% central range, CR: 14.71-17.39 m CHF) in 2008 and 14.89 m CHF (90% CR: 13.72-16.08 m CHF) in 2009. The break-even point was estimated to be reached in 2012 and the margin over eradication cost 63.15m CHF (90% CR: 53.72-72.82 m CHF). The discounted cost for each surveillance strategy was found to be smaller than the margin, so the mitigation programme overall is expected to have a positive net economic benefit irrespective of the strategy adopted. For economic efficiency, the least cost surveillance alternative must be selected. Copyright © 2012 Elsevier B.V. All rights reserved.

Potentials for sustainable transportation in cities to alleviate climate change impacts.

PubMed

Mashayekh, Yeganeh; Jaramillo, Paulina; Samaras, Constantine; Hendrickson, Chris T; Blackhurst, Michael; MacLean, Heather L; Matthews, H Scott

2012-03-06

Reducing greenhouse gas emissions (GHG) is an important social goal to mitigate climate change. A common mitigation paradigm is to consider strategy "wedges" that can be applied to different activities to achieve desired GHG reductions. In this policy analysis piece, we consider a wide range of possible strategies to reduce light-duty vehicle GHG emissions, including fuel and vehicle options, low carbon and renewable power, travel demand management and land use changes. We conclude that no one strategy will be sufficient to meet GHG emissions reduction goals to avoid climate change. However, many of these changes have positive combinatorial effects, so the best strategy is to pursue combinations of transportation GHG reduction strategies to meet reduction goals. Agencies need to broaden their agendas to incorporate such combination in their planning.

Update on Common-Cause Failure Experience and Mitigation Practices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wood, Richard Thomas; Muhlheim, Michael David; Pullum, Laura L

2014-04-01

Experience in other industries has shown that digital technology can provide substantial benefits in terms of performance and reliability. However, the U.S. nuclear power industry has been slow to adopt the technology extensively in its instrumentation and control (I&C) applications because of inhibiting factors such as regulatory uncertainty, insufficient technological experience base, implementation complexity, limited availability of nuclear-qualified products and vendors, and inadequate definition of modernization cost recapture. Although there have been examples of digital technology usage in the nuclear power industry, challenges to the qualification of digital technology for high-integrity nuclear power plant (NPP) applications have severely constrained moremore » widespread progress in achieving the benefits that are possible through the transition to digital. The U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) established the Advanced Sensors and Instrumentation (ASI) technology area under the Nuclear Energy Enabling Technologies (NEET) Program to coordinate the instrumentation and controls (I&C) research across DOE NE and to identify and lead efforts to address common needs. As part of the NEET ASI research program, the Digital Technology Qualification project was established. Under this project, the Oak Ridge National Laboratory (ORNL) is leading the investigation into mitigation of digital common-cause failure (CCF) vulnerabilities for nuclear-qualified applications. This technical report documents updated and expanded findings from research activities by ORNL. Specifically, the report describes CCF experience in the nuclear and nonnuclear industries, identifies the state of the practice for CCF mitigation through key examples, and presents conclusions from the determination of knowledge gaps.« less

Development of a national system for prevention and mitigation of earthquake damages to people and properties, and the reduction of costs related to earthquakes for the Italian Government

NASA Astrophysics Data System (ADS)

Console, R.; Greco, M.; Colangelo, A.; Cioè, A.; Trivigno, L.; Chiappini, M.; Ponzo, F.

2015-12-01

Recognizing that the Italian territory is prone to disasters in connection with seismic and hydro-geological risk, it has become necessary to define novel regulations and viable solutions aimed at conveying the economical resources of the Italian Government, too often utilized for the management of post-event situations, towards prevention activities. The work synthetically presents the project developed by the CGIAM together with the INGV, and open to collaboration with other Italian and International partners. This project is aimed at the development of a National System for prevention and mitigation of the earthquakes damages, through the definition of a model that achieves the mitigation of the building collapsing risk and the consequent reduction of casualties. Such a model is based on two main issues a) a correct evaluation of risk, defined as a reliable assessment of the hazard expected at a given site and of the vulnerability of civil and industrial buildings, b) setting up of novel strategies for the safety of buildings. The hazard assessment is pursued through the application of innovative multidisciplinary geophysical methodologies and the application of a physically based earthquake simulator. The structural vulnerability of buildings is estimated by means of simplified techniques based on few representative parameters (such as different structural typologies, dynamic soil-structure interaction, etc.) and, for detailed studies, standard protocols for model updating techniques. We analyze, through numerical and experimental approaches, new solutions for the use of innovative materials, and new techniques for the reduction of seismic vulnerability of structural, non-structural and accessorial elements, including low cost type. The project activities are initially implemented on a study area in Southern Italy (Calabria) selected because of its tectonic complexity. The results are expected to be applicable for other hazardous seismic areas of Italy.

Historic and future trends of vehicle emissions in Beijing, 1998-2020: A policy assessment for the most stringent vehicle emission control program in China

NASA Astrophysics Data System (ADS)

Zhang, Shaojun; Wu, Ye; Wu, Xiaomeng; Li, Mengliang; Ge, Yunshan; Liang, Bin; Xu, Yueyun; Zhou, Yu; Liu, Huan; Fu, Lixin; Hao, Jiming

2014-06-01

As a pioneer in controlling vehicle emissions within China, Beijing released the Clean Air Action Plan 2013-2017 document in August 2013 to improve its urban air quality. It has put forward this plan containing the most stringent emission control policies and strategies to be adopted for on-road vehicles of Beijing. This paper estimates the historic and future trends and uncertainties in vehicle emissions of Beijing from 1998 to 2020 by applying a new emission factor model for the Beijing vehicle fleet (EMBEV). Our updated results show that total emissions of CO, THC, NOx and PM2.5 from the Beijing vehicle fleet are 507 (395-819) kt, 59.1 (41.2-90.5) kt, 74.7 (54.9-103.9) kt and 2.69 (1.91-4.17) kt, respectively, at a 95% confidence level. This represents significant reductions of 58%, 59%, 31% and 62%, respectively, relative to the total vehicle emissions in 1998. The past trends clearly posed a challenge to NOx emission mitigation for the Beijing vehicle fleet, especially in light of those increasing NOx emissions from heavy-duty diesel vehicles (HDDVs) which have partly offset the reduction benefit from light-duty gasoline vehicles (LDGVs). Because of recently announced vehicle emission controls to be adopted in Beijing, including tighter emissions standards, limitations on vehicle growth by more stringent license control, promotion of alternative fuel technologies (e.g., natural gas) and the scrappage of older vehicles, estimated vehicle emissions in Beijing will continue to be mitigated by 74% of CO, 68% of THC, 56% of NOx and 72% of PM2.5 in 2020 compared to 2010 levels. Considering that many of the megacities in China are facing tremendous pressures to mitigate emissions from on-road vehicles, our assessment will provide a timely case study of significance for policy-makers in China.

Evaluation of noise impact mitigation protocols to support CSS : final report.

DOT National Transportation Integrated Search

2008-03-01

This research project developed and evaluated practical ways of involving the public in context sensitive sound mitigation strategies. The integrated use of photo montage, PowerPoint presentation, linked traffic sound files, and audience response sys...

Future management strategies for state maintained wetlands and stream mitigation sites.

DOT National Transportation Integrated Search

2008-06-01

This study was to identify existing wetland/stream mitigation sites owned by the Kentucky Transportation Cabinet (KYTC) and assess performance of those sites including problems encountered and maintenance costs. Initial work determined that KYTC Dist...

An Investigation of Corrosion Mitigation Strategies for Aging Post Tensioned Cables

DTIC Science & Technology

2017-01-01

ER D C/ IT L TR -1 7- 1 Navigation Systems Research Program An Investigation of Corrosion Mitigation Strategies for Aging Post -Tensioned...for Aging Post -Tensioned Cables Ernest L. Miller, Barry C. White, Richard W. Haskins, Robert M. Ebeling, and James A. Evans Information Technology...Reduced Capacity of Multistrand Post Tensioned Ground Anchorage Due to Tendon Corrosion Work Unit number L9C833 ERDC/ITL TR-17-1 ii Abstract Over

An Investigation of Corrosion Mitigation Strategies for Aging Post-Tensioned Cables

DTIC Science & Technology

2017-01-01

ER D C/ IT L TR -1 7- 1 Navigation Systems Research Program An Investigation of Corrosion Mitigation Strategies for Aging Post -Tensioned...for Aging Post -Tensioned Cables Ernest L. Miller, Barry C. White, Richard W. Haskins, Robert M. Ebeling, and James A. Evans Information Technology...Reduced Capacity of Multistrand Post Tensioned Ground Anchorage Due to Tendon Corrosion Work Unit number L9C833 ERDC/ITL TR-17-1 ii Abstract Over

Uncovering and Validating Toughening Mechanisms in High Performance Composites

DTIC Science & Technology

2015-09-17

striated regions have similar microstructures (see Figure 44). This aligned, fiber-reinforced design of the striated region has been adapted from spearing...Page 79 / 84 “Fracture mitigation strategies in gastropod shells,” C. Salinas and D. Kisailus, Journal of Materials, 65 (4) (2013) 473-480. DOI...2014.03.022 “Fracture mitigation strategies in gastropod shells,” C. Salinas and D. Kisailus, Journal of Materials, 65 (4) (2013) 473-480. DOI: J10.1007

A robust control strategy for mitigating renewable energy fluctuations in a real hybrid power system combined with SMES

NASA Astrophysics Data System (ADS)

Magdy, G.; Shabib, G.; Elbaset, Adel A.; Qudaih, Yaser; Mitani, Yasunori

2018-05-01

Utilizing Renewable Energy Sources (RESs) is attracting great attention as a solution to future energy shortages. However, the irregular nature of RESs and random load deviations cause a large frequency and voltage fluctuations. Therefore, in order to benefit from a maximum capacity of the RESs, a robust mitigation strategy of power fluctuations from RESs must be applied. Hence, this paper proposes a design of Load Frequency Control (LFC) coordinated with Superconducting Magnetic Energy Storage (SMES) technology (i.e., an auxiliary LFC), using an optimal PID controller-based Particle Swarm Optimization (PSO) in the Egyptian Power System (EPS) considering high penetration of Photovoltaics (PV) power generation. Thus, from the perspective of LFC, the robust control strategy is proposed to maintain the nominal system frequency and mitigating the power fluctuations from RESs against all disturbances sources for the EPS with the multi-source environment. The EPS is decomposed into three dynamics subsystems, which are non-reheat, reheat and hydro power plants taking into consideration the system nonlinearity. The results by nonlinear simulation Matlab/Simulink for the EPS combined with SMES system considering PV solar power approves that, the proposed control strategy achieves a robust stability by reducing transient time, minimizing the frequency deviations, maintaining the system frequency, preventing conventional generators from exceeding their power ratings during load disturbances, and mitigating the power fluctuations from the RESs.

Shared responsibility for managing fatigue: Hearing the pilots

PubMed Central

O’Keeffe, Karyn M.; Signal, T. Leigh; Gander, Philippa H.

2018-01-01

In commercial aviation, fatigue is defined as a physiological state of reduced mental or physical performance capability resulting from sleep loss, extended wakefulness, circadian phase, and/or workload. The International Civil Aviation Organisation mandates that responsibility for fatigue risk management is shared between airline management, pilots, and support staff. However, to date, the majority of research relating to fatigue mitigations in long range operations has focused on the mitigations required or recommended by regulators and operators. Little research attention has been paid to the views or operational experience of the pilots who use these (or other) mitigations. This study focused on pilots’ views and experiences of in-flight sleep as the primary fatigue mitigation on long range flights. It also sought information about other fatigue mitigation strategies they use. Thematic analysis was used to explore written comments from diary and survey data collected during long range and ultra-long range trips (N = 291 pilots on three different aircraft types, 17 different out-and-back trips, and four airlines based on three continents). The findings indicate that the recommended fatigue mitigation strategies on long-haul flights (particularly in-flight sleep) are effective and well-utilised, consistent with quantitative findings from the same trips. Importantly however, the analyses also highlight areas that require further investigation, including flight preparation strategies in relation to the uncertainty of in-flight break allocation. There were two strategies for sleep prior to a flight: maximising sleep if pilots were expecting later breaks in the flight; or minimising sleep if they were expecting breaks earlier or at unfavourable times in the circadian cycle. They also provide a broader view of the factors that affect the amount and quality of pilots’ in-flight sleep, about which evidence has previously been largely anecdotal. The study underscores the value of including the views and experience of pilots in fatigue risk management. PMID:29782533

Inclusion of climate change strategies in municipal Integrated Development Plans: A case from seven municipalities in Limpopo Province, South Africa

PubMed Central

2016-01-01

The Intergovernmental Panel on Climate Change (IPCC) has made it clear that anthropogenic greenhouse gasses are the main cause of observed global warming that leads to climate change. Climate change is now a global reality. In the South African political set-up, local municipalities are the structures that are in direct contact with communities and they draw up Integrated Development Plans (IDPs), which are reviewed and upgraded annually. The article seeks to investigate the extent to which climate change adaptation and mitigation strategies are embedded IDPs in seven vulnerable municipalities in the Limpopo Province. The article conducted an in-depth content analysis of the IDPs of the seven municipalities and the results have revealed that these municipalities have not included adaptation and mitigation strategies adequately in their IDPs despite being the most vulnerable municipalities in the province. The article concludes that these municipalities have not as yet institutionalised climate change in their daily operations, planning and decision making. To this end, the paper recommends that local municipalities should include climate change adaptation and mitigation strategies in their IDPs.

Mitigating cyanobacterial harmful algal blooms in aquatic ecosystems impacted by climate change and anthropogenic nutrients.

PubMed

Paerl, Hans W; Gardner, Wayne S; Havens, Karl E; Joyner, Alan R; McCarthy, Mark J; Newell, Silvia E; Qin, Boqiang; Scott, J Thad

2016-04-01

Mitigating the global expansion of cyanobacterial harmful blooms (CyanoHABs) is a major challenge facing researchers and resource managers. A variety of traditional (e.g., nutrient load reduction) and experimental (e.g., artificial mixing and flushing, omnivorous fish removal) approaches have been used to reduce bloom occurrences. Managers now face the additional effects of climate change on watershed hydrologic and nutrient loading dynamics, lake and estuary temperature, mixing regime, internal nutrient dynamics, and other factors. Those changes favor CyanoHABs over other phytoplankton and could influence the efficacy of control measures. Virtually all mitigation strategies are influenced by climate changes, which may require setting new nutrient input reduction targets and establishing nutrient-bloom thresholds for impacted waters. Physical-forcing mitigation techniques, such as flushing and artificial mixing, will need adjustments to deal with the ramifications of climate change. Here, we examine the suite of current mitigation strategies and the potential options for adapting and optimizing them in a world facing increasing human population pressure and climate change. Copyright © 2015 Elsevier B.V. All rights reserved.

Insurability and mitigation of flood losses in private households in Germany.

PubMed

Thieken, Annegret H; Petrow, Theresia; Kreibich, Heidi; Merz, Bruno

2006-04-01

In Germany, flood insurance is provided by private insurers as a supplement to building or contents insurance. This article presents the results of a survey of insurance companies with regard to eligibility conditions for flood insurance changes after August 2002, when a severe flood caused 1.8 billion euro of insured losses in the Elbe and the Danube catchment areas, and the general role of insurance in flood risk management in Germany. Besides insurance coverage, governmental funding and public donations played an important role in loss compensation after the August 2002 flood. Therefore, this article also analyzes flood loss compensation, risk awareness, and mitigation in insured and uninsured private households. Insured households received loss compensation earlier. They also showed slightly better risk awareness and mitigation strategies. Appropriate incentives should be combined with flood insurance in order to strengthen future private flood loss mitigation. However, there is some evidence that the surveyed insurance companies do little to encourage precautionary measures. To overcome this problem, flood hazards and mitigation strategies should be better communicated to both insurance companies and property owners.

Best Mitigation Paths To Effectively Reduce Earth's Orbital Debris

NASA Technical Reports Server (NTRS)

Wiegman, Bruce M.

2009-01-01

This slide presentation reviews some ways to reduce the problem posed by debris in orbit around the Earth. It reviews the orbital debris environment, the near-term needs to minimize the Kessler syndrome, also known as collisional cascading, a survey of active orbital debris mitigation strategies, the best paths to actively remove orbital debris, and technologies that are required for active debris mitigation.

Y-12 Site environmental protection program implementation plan (EPPIP)

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-11-01

The Y-12 Plant Environmental Protection Program is conducted to: (1) protect public health and the environment from chemical and radiological releases occurring from current plant operations and past waste management and operational practices; (2) ensure compliance with federal, state, and local environmental regulations and DOE directives; (3) identify potential environmental problems; (4) evaluate existing environmental contamination and determine the need for remedial actions and mitigative measures; (5) monitor the progress of ongoing remedial actions and cleanup measures; and (6) inform the public of environmental issues relating to DOE operations. DOE Order 5400.1, General Environmental Protection Program, defines the general requirementsmore » for environmental protection programs at DOE facilities. This Environmental Protection Program Implementation Plan (EPPIP) defines the methods by which the Y-12 Plant staff will comply with the order by: (1) referencing environmental protection goals and objectives and identifying strategies and timetables for attaining them; (2) providing the overall framework for the design and implementation of the Y-12 Environmental Protection Program; and (3) assigning responsibilities for complying with the requirements of the order. The EPPIP is revised and updated annually.« less

Implications of Integrating Women into USMC Infantry

DTIC Science & Technology

2015-01-01

well-defined, updated, and clearly communicated sexual harassment policies; and procedures to ensure that women receive equal training and...traditionally male groups depends on the culture of the group: Groups more hostile to women experience lower cohesion after gender integration than do...creates a hostile environment for women. A variety of efforts can mitigate whatever detrimental effects integration of women would have on male -dominated

Department of Defense Best Management Practices for Munitions Constituents on Operational Ranges

DTIC Science & Technology

2014-04-01

website for updates on currently funded plant-based mitigation projects. Key Resources: Best EPH, Smith JC, Ringelberg DB. 2009. Phytoremediation of...Bruce N. 2012. Sustainable Range Management of RDX and TNT by Phytoremediation with Engineered Plants. SERDP Project ER-1498 Fact Sheet. Schnoor...J. 2011. Phytoremediation for the Containment and Treatment of Energetic and Propellant Material Releases on Testing and Training Ranges. SERDP

Hawaiian cultural influences on support for lava flow hazard mitigation measures during the January 1960 eruption of Kīlauea volcano, Kapoho, Hawai‘i

NASA Astrophysics Data System (ADS)

Gregg, C. E.; Houghton, B. F.; Paton, D.; Swanson, D. A.; Lachman, R.; Bonk, W. J.

2008-05-01

In 1960, Kīlauea volcano in Hawaii erupted, destroying most of the village of Kapoho and forcing evacuation of its approximately 300 residents. A large and unprecedented social science survey was undertaken during the eruption to develop an understanding of human behavior, beliefs, and coping strategies among the adult evacuees ( n = 160). Identical studies were also performed in three control towns located at varying distances from the eruption site ( n = 478). During these studies data were collected that characterized ethnic grouping and attitudes toward Hawaiian cultural issues such as belief in Pele and two lava flow mitigation measures—use of barriers and bombs to influence the flow of lava, but the data were never published. Using these forgotten data, we examined the relationship between Hawaiian cultural issues and attitudes toward the use of barriers and bombs as mitigation strategies to protect Kapoho. On average, 72% of respondents favored the construction of earthen barriers to hold back or divert lava and protect Kapoho, but far fewer agreed with the military's use of bombs (14%) to protect Kapoho. In contrast, about one-third of respondents conditionally agreed with the use of bombs. It is suggested that local participation in the bombing strategy may explain the increased conditional acceptance of bombs as a mitigation tool, although this can not be conclusively demonstrated. Belief in Pele and being of Hawaiian ethnicity did not reduce support for the use of barriers, but did reduce support for bombs in both bombing scenarios. The disparity in levels of acceptance of barriers versus bombing and of one bombing strategy versus another suggests that historically public attitudes toward lava flow hazard mitigation strategies were complex. A modern comparative study is needed before the next damaging eruption to inform debates and decisions about whether or not to interfere with the flow of lava. Recent changes in the current eruption of Kīlauea make this a timely topic.

Vegetation and other development options for mitigating urban air pollution impacts

EPA Science Inventory

In addition to installing air pollution control devices and reducing emissions activities, urban air pollution can be further mitigated through planning and design strategies including vegetation planting, building design, installing roadside and near source structures, and modif...

A simulation-optimization-based decision support tool for mitigating traffic congestion.

DOT National Transportation Integrated Search

2009-12-01

"Traffic congestion has grown considerably in the United States over the past twenty years. In this paper, we develop : a robust decision support tool based on simulation optimization to evaluate and recommend congestion-mitigation : strategies to tr...

Science framework for conservation and restoration of the sagebrush biome: Linking the Department of the Interior’s Integrated Rangeland Fire Management Strategy to long-term strategic conservation actions, Part 1. Science basis and applications

USGS Publications Warehouse

Chambers, Jeanne C.; Beck, Jeffrey L.; Bradford, John B.; Bybee, Jared; Campbell, Steve; Carlson, John; Christiansen, Thomas J; Clause, Karen J.; Collins, Gail; Crist, Michele R.; Dinkins, Jonathan B.; Doherty, Kevin E.; Edwards, Fred; Espinosa, Shawn; Griffin, Kathleen A.; Griffin, Paul; Haas, Jessica R.; Hanser, Steven E.; Havlina, Douglas W.; Henke, Kenneth F.; Hennig, Jacob D.; Joyce, Linda A; Kilkenny, Francis F.; Kulpa, Sarah M; Kurth, Laurie L; Maestas, Jeremy D; Manning, Mary E.; Mayer, Kenneth E.; Mealor, Brian A.; McCarthy, Clinton; Pellant, Mike; Perea, Marco A.; Prentice, Karen L.; Pyke, David A.; Wiechman , Lief A.; Wuenschel, Amarina

2017-01-01

The Science Framework is intended to link the Department of the Interior’s Integrated Rangeland Fire Management Strategy with long-term strategic conservation actions in the sagebrush biome. The Science Framework provides a multiscale approach for prioritizing areas for management and determining effective management strategies within the sagebrush biome. The emphasis is on sagebrush (Artemisia spp.) ecosystems and Greater sage-grouse (Centrocercus urophasianus). The approach provided in the Science Framework links sagebrush ecosystem resilience to disturbance and resistance to nonnative, invasive plant species to species habitat information based on the distribution and abundance of focal species. A geospatial process is presented that overlays information on ecosystem resilience and resistance, species habitats, and predominant threats and that can be used at the mid-scale to prioritize areas for management. A resilience and resistance habitat matrix is provided that can help decisionmakers evaluate risks and determine appropriate management strategies. Prioritized areas and management strategies can be refined by managers and stakeholders at the local scale based on higher resolution data and local knowledge. Decision tools are discussed for determining appropriate management actions for areas that are prioritized for management. Geospatial data, maps, and models are provided through the U.S. Geological Survey (USGS) ScienceBase and Bureau of Land Management (BLM) Landscape Approach Data Portal. The Science Framework is intended to be adaptive and will be updated as additional data become available on other values and species at risk. It is anticipated that the Science Framework will be widely used to: (1) inform emerging strategies to conserve sagebrush ecosystems, sagebrush dependent species, and human uses of the sagebrush system, and (2) assist managers in prioritizing and planning on-the-ground restoration and mitigation actions across the sagebrush biome.

Evolutionary fate of memory-one strategies in repeated prisoner's dilemma game in structured populations

NASA Astrophysics Data System (ADS)

Liu, Xu-Sheng; Wu, Zhi-Xi; Chen, Michael Z. Q.; Guan, Jian-Yue

2017-07-01

We study evolutionary spatial prisoner's dilemma game involving a one-step memory mechanism of the individuals whenever making strategy updating. In particular, during the process of strategy updating, each individual keeps in mind all the outcome of the action pairs adopted by himself and each of his neighbors in the last interaction, and according to which the individuals decide what actions they will take in the next round. Computer simulation results imply that win-stay-lose-shift like strategy win out of the memory-one strategy set in the stationary state. This result is robust in a large range of the payoff parameter, and does not depend on the initial state of the system. Furthermore, theoretical analysis with mean field and quasi-static approximation predict the same result. Thus, our studies suggest that win-stay-lose-shift like strategy is a stable dominant strategy in repeated prisoner's dilemma game in homogeneous structured populations.

Toward a Comprehensive Strategy to Mitigate Dissemination of Environmental Sources of Antibiotic Resistance.

PubMed

Vikesland, Peter J; Pruden, Amy; Alvarez, Pedro J J; Aga, Diana; Bürgmann, Helmut; Li, Xiang-Dong; Manaia, Celia M; Nambi, Indumathi; Wigginton, Krista; Zhang, Tong; Zhu, Yong-Guan

2017-11-21

Antibiotic resistance is a pervasive global health threat. To combat the spread of resistance, it is necessary to consider all possible sources and understand the pathways and mechanisms by which resistance disseminates. Best management practices are urgently needed to provide barriers to the spread of resistance and maximize the lifespan of antibiotics as a precious resource. Herein we advise upon the need for coordinated national and international strategies, highlighting three essential components: (1) Monitoring, (2) Risk Assessment, and (3) Mitigation of antibiotic resistance. Central to all three components is What exactly to monitor, assess, and mitigate? We address this question within an environmental framework, drawing from fundamental microbial ecological processes driving the spread of resistance.

National-level infrastructure and economic effects of switchgrass cofiring with coal in existing power plants for carbon mitigation.

PubMed

Morrow, William R; Griffin, W Michael; Matthews, H Scott

2008-05-15

We update a previously presented Linear Programming (LP) methodology for estimating state level costs for reducing CO2 emissions from existing coal-fired power plants by cofiring switchgrass, a biomass energy crop, and coal. This paper presents national level results of applying the methodology to the entire portion of the United States in which switchgrass could be grown without irrigation. We present incremental switchgrass and coal cofiring carbon cost of mitigation curves along with a presentation of regionally specific cofiring economics and policy issues. The results show that cofiring 189 million dry short tons of switchgrass with coal in the existing U.S. coal-fired electricity generation fleet can mitigate approximately 256 million short tons of carbon-dioxide (CO2) per year, representing a 9% reduction of 2005 electricity sector CO2 emissions. Total marginal costs, including capital, labor, feedstock, and transportation, range from $20 to $86/ton CO2 mitigated,with average costs ranging from $20 to $45/ton. If some existing power plants upgrade to boilers designed for combusting switchgrass, an additional 54 million tons of switchgrass can be cofired. In this case, total marginal costs range from $26 to $100/ton CO2 mitigated, with average costs ranging from $20 to $60/ton. Costs for states east of the Mississippi River are largely unaffected by boiler replacement; Atlantic seaboard states represent the lowest cofiring cost of carbon mitigation. The central plains states west of the Mississippi River are most affected by the boiler replacement option and, in general, go from one of the lowest cofiring cost of carbon mitigation regions to the highest. We explain the variation in transportation expenses and highlight regional cost of mitigation variations as transportation overwhelms other cofiring costs.

Towards an integrated defense system for cyber security situation awareness experiment

NASA Astrophysics Data System (ADS)

Zhang, Hanlin; Wei, Sixiao; Ge, Linqiang; Shen, Dan; Yu, Wei; Blasch, Erik P.; Pham, Khanh D.; Chen, Genshe

2015-05-01

In this paper, an implemented defense system is demonstrated to carry out cyber security situation awareness. The developed system consists of distributed passive and active network sensors designed to effectively capture suspicious information associated with cyber threats, effective detection schemes to accurately distinguish attacks, and network actors to rapidly mitigate attacks. Based on the collected data from network sensors, image-based and signals-based detection schemes are implemented to detect attacks. To further mitigate attacks, deployed dynamic firewalls on hosts dynamically update detection information reported from the detection schemes and block attacks. The experimental results show the effectiveness of the proposed system. A future plan to design an effective defense system is also discussed based on system theory.

Conceptualising the technical relationship of animal disease surveillance to intervention and mitigation as a basis for economic analysis

PubMed Central

2011-01-01

Background Surveillance and intervention are resource-using activities of strategies to mitigate the unwanted effects of disease. Resources are scarce, and allocating them to disease mitigation instead of other uses necessarily involves the loss of alternative sources of benefit to people. For society to obtain the maximum benefits from using resources, the gains from disease mitigation must be compared to the resource costs, guiding decisions made with the objective of achieving the optimal net outcome. Discussion Economics provides criteria to guide decisions aimed at optimising the net benefits from the use of scarce resources. Assessing the benefits of disease mitigation is no exception. However, the technical complexity of mitigation means that economic evaluation is not straightforward because of the technical relationship of surveillance to intervention. We argue that analysis of the magnitudes and distribution of benefits and costs for any given strategy, and hence the outcome in net terms, requires that mitigation is considered in three conceptually distinct stages. In Stage I, 'sustainment', the mitigation objective is to sustain a free or acceptable status by preventing an increase of a pathogen or eliminating it when it occurs. The role of surveillance is to document that the pathogen remains below a defined threshold, giving early warning of an increase in incidence or other significant changes in risk, and enabling early response. If a pathogen is not contained, the situation needs to be assessed as Stage II, 'investigation'. Here, surveillance obtains critical epidemiological information to decide on the appropriate intervention strategy to reduce or eradicate a disease in Stage III, 'implementation'. Stage III surveillance informs the choice, timing, and scale of interventions and documents the progress of interventions directed at prevalence reduction in the population. Summary This article originates from a research project to develop a conceptual framework and practical tool for the economic evaluation of surveillance. Exploring the technical relationship between mitigation as a source of economic value and surveillance and intervention as sources of economic cost is crucial. A framework linking the key technical relationships is proposed. Three conceptually distinct stages of mitigation are identified. Avian influenza, salmonella, and foot and mouth disease are presented to illustrate the framework. PMID:21929812

Playing against nature: improving earthquake hazard mitigation

NASA Astrophysics Data System (ADS)

Stein, S. A.; Stein, J.

2012-12-01

The great 2011 Tohoku earthquake dramatically demonstrated the need to improve earthquake and tsunami hazard assessment and mitigation policies. The earthquake was much larger than predicted by hazard models, and the resulting tsunami overtopped coastal defenses, causing more than 15,000 deaths and $210 billion damage. Hence if and how such defenses should be rebuilt is a challenging question, because the defences fared poorly and building ones to withstand tsunamis as large as March's is too expensive,. A similar issue arises along the Nankai Trough to the south, where new estimates warning of tsunamis 2-5 times higher than in previous models raise the question of what to do, given that the timescale on which such events may occur is unknown. Thus in the words of economist H. Hori, "What should we do in face of uncertainty? Some say we should spend our resources on present problems instead of wasting them on things whose results are uncertain. Others say we should prepare for future unknown disasters precisely because they are uncertain". Thus society needs strategies to mitigate earthquake and tsunami hazards that make economic and societal sense, given that our ability to assess these hazards is poor, as illustrated by highly destructive earthquakes that often occur in areas predicted by hazard maps to be relatively safe. Conceptually, we are playing a game against nature "of which we still don't know all the rules" (Lomnitz, 1989). Nature chooses tsunami heights or ground shaking, and society selects the strategy to minimize the total costs of damage plus mitigation costs. As in any game of chance, we maximize our expectation value by selecting the best strategy, given our limited ability to estimate the occurrence and effects of future events. We thus outline a framework to find the optimal level of mitigation by balancing its cost against the expected damages, recognizing the uncertainties in the hazard estimates. This framework illustrates the role of the uncertainties and the need to candidly assess them. It can be applied to exploring policies under various hazard scenarios and mitigating other natural hazards.ariation in total cost, the sum of expected loss and mitigation cost, as a function of mitigation level. The optimal level of mitigation, n*, minimizes the total cost. The expected loss depends on the hazard model, so the better the hazard model, the better the mitigation policy (Stein and Stein, 2012).

Silicon Nano-tips and Related Nano-Systems Involving Fluid and Carrier Transport for Miniaturized Spacecraft Power and Sensing Applications

DTIC Science & Technology

2015-02-02

the nanoscale. Through this research, the two fundamental life-limiting issues of ILIS operation have been identified and mitigated: electrochemical ...this research, the two fundamental life-limiting issues of ILIS operation have been identified and mitigated: electrochemical degradation and gas...identified and mitigated: electrochemical degradation and gas discharges. A distal electrode configuration was proposed and verified as a strategy

Modeling with uncertain science: estimating mitigation credits from abating lead poisoning in Golden Eagles.

PubMed

Fitts Cochrane, Jean; Lonsdorf, Eric; Allison, Taber D; Sanders-Reed, Carol A

2015-09-01

Challenges arise when renewable energy development triggers "no net loss" policies for protected species, such as where wind energy facilities affect Golden Eagles in the western United States. When established mitigation approaches are insufficient to fully avoid or offset losses, conservation goals may still be achievable through experimental implementation of unproven mitigation methods provided they are analyzed within a framework that deals transparently and rigorously with uncertainty. We developed an approach to quantify and analyze compensatory mitigation that (1) relies on expert opinion elicited in a thoughtful and structured process to design the analysis (models) and supplement available data, (2) builds computational models as hypotheses about cause-effect relationships, (3) represents scientific uncertainty in stochastic model simulations, (4) provides probabilistic predictions of "relative" mortality with and without mitigation, (5) presents results in clear formats useful to applying risk management preferences (regulatory standards) and selecting strategies and levels of mitigation for immediate action, and (6) defines predictive parameters in units that could be monitored effectively, to support experimental adaptive management and reduction in uncertainty. We illustrate the approach with a case study characterized by high uncertainty about underlying biological processes and high conservation interest: estimating the quantitative effects of voluntary strategies to abate lead poisoning in Golden Eagles in Wyoming due to ingestion of spent game hunting ammunition.

Mitigating circumstances in death penalty decisions: using evidence-based research to inform social work practice in capital trials.

PubMed

Schroeder, Julie; Guin, Cecile C; Pogue, Rene; Bordelon, Danna

2006-10-01

Providing an effective defense for individuals charged with capital crimes requires a diligent, thorough investigation by a mitigation specialist. However, research suggests that mitigation often plays a small role in the decision for life. Jurors often make sentencing decisions prematurely, basing those decisions on their personal reactions to the defendant (for example, fear, anger), their confusion about the rules of law, and their lack of understanding regarding their role and responsibilities. This article proposes an evidence-based conceptual model of the complicating problems surrounding mitigation practice and a focused discussion about how traditional social work mitigation strategies might be evolved to a set of best practices that more effectively ensure jurors' careful consideration of mitigation evidence.

An Optimal Mitigation Strategy Against the Asteroid Impact Threat with Short Warning Time

NASA Technical Reports Server (NTRS)

Wie, Bong; Barbee, Brent; Pitz, Alan; Kaplinger, Brian; Hawkins, Matt; Winkler, Tim; Premaratne, Pavithra; Vardaxis, George; Lyzhoft, Joshua; Zimmerman, Ben

2015-01-01

To develop an innovative yet practically implementable mitigation technique for the most probable impact threat of an asteroid or comet with short warning time (i.e., when we don't have sufficient warning times for a deflection mission).

Between universalism and relativism: a conceptual exploration of problems in formulating and applying international biomedical ethical guidelines.

PubMed

Tangwa, G B

2004-02-01

In this paper, the author attempts to explore some of the problems connected with the formulation and application of international biomedical ethical guidelines, with particular reference to Africa. Recent attempts at revising and updating some international medical ethical guidelines have been bedevilled by intractable controversies and wrangling regarding both the content and formulation. From the vantage position of relative familiarity with both African and Western contexts, and the privilege of having been involved in the revision and updating of one of the international ethical guidelines, the author reflects broadly on these issues and attempts prescribing an approach from both the theoretical and practical angles liable to mitigate, if not completely eliminate, some of the problems and difficulties.

Andrea Watson | NREL

Science.gov Websites

energy solutions for emission mitigation, international climate change strategies, and renewable energy technical decision making. Andrea's expertise lies in strategic planning, change strategies, and decision

Cooperation and charity in spatial public goods game under different strategy update rules

NASA Astrophysics Data System (ADS)

Li, Yixiao; Jin, Xiaogang; Su, Xianchuang; Kong, Fansheng; Peng, Chengbin

2010-03-01

Human cooperation can be influenced by other human behaviors and recent years have witnessed the flourishing of studying the coevolution of cooperation and punishment, yet the common behavior of charity is seldom considered in game-theoretical models. In this article, we investigate the coevolution of altruistic cooperation and egalitarian charity in spatial public goods game, by considering charity as the behavior of reducing inter-individual payoff differences. Our model is that, in each generation of the evolution, individuals play games first and accumulate payoff benefits, and then each egalitarian makes a charity donation by payoff transfer in its neighborhood. To study the individual-level evolutionary dynamics, we adopt different strategy update rules and investigate their effects on charity and cooperation. These rules can be classified into two global rules: random selection rule in which individuals randomly update strategies, and threshold selection rule where only those with payoffs below a threshold update strategies. Simulation results show that random selection enhances the cooperation level, while threshold selection lowers the threshold of the multiplication factor to maintain cooperation. When charity is considered, it is incapable in promoting cooperation under random selection, whereas it promotes cooperation under threshold selection. Interestingly, the evolution of charity strongly depends on the dispersion of payoff acquisitions of the population, which agrees with previous results. Our work may shed light on understanding human egalitarianism.

Embodied carbon mitigation and reduction in the built environment - What does the evidence say?

PubMed

Pomponi, Francesco; Moncaster, Alice

2016-10-01

Of all industrial sectors, the built environment puts the most pressure on the natural environment, and in spite of significant efforts the International Energy Agency suggests that buildings-related emissions are on track to double by 2050. Whilst operational energy efficiency continues to receive significant attention by researchers, a less well-researched area is the assessment of embodied carbon in the built environment in order to understand where the greatest opportunities for its mitigation and reduction lie. This article approaches the body of academic knowledge on strategies to tackle embodied carbon (EC) and uses a systematic review of the available evidence to answer the following research question: how should we mitigate and reduce EC in the built environment? 102 journal articles have been reviewed systematically in the fields of embodied carbon mitigation and reduction, and life cycle assessment. In total, 17 mitigation strategies have been identified from within the existing literature which have been discussed through a meta-analysis on available data. Results reveal that no single mitigation strategy alone seems able to tackle the problem; rather, a pluralistic approach is necessary. The use of materials with lower EC, better design, an increased reuse of EC-intensive materials, and stronger policy drivers all emerged as key elements for a quicker transition to a low carbon built environment. The meta-analysis on 77 LCAs also shows an extremely incomplete and short-sighted approach to life cycle studies. Most studies only assess the manufacturing stages, often completely overlooking impacts occurring during the occupancy stage and at the end of life of the building. The LCA research community have the responsibility to address such shortcomings and work towards more complete and meaningful assessments. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

Evidence for the value of health promotion interventions in natural disaster management.

PubMed

Jackson, Suzanne F; Fazal, Nadia; Gravel, Geneviève; Papowitz, Heather

2017-12-01

A rapid review of literature was conducted to identify effective health promotion (HP) intervention strategies that relate to the management of disasters from natural hazards, including prevention, preparedness, response and recovery measures. Searches were conducted in formal literature from 2000 to 2011 and then updated to 2013. Out of 719 relevant abstracts, 57 studies were selected for more detailed review. In total, 16 studies were annotated for the narrative synthesis; these articles all reported an outcome-oriented evaluation of an HP-related intervention in a natural disaster situation in low- and middle-income countries (LMIC) or vulnerable populations in high-income countries (HIC). These 16 studies were also assessed for quality of their evaluation design. Although it was not possible to select only strong study designs, LMIC weak designs were matched with stronger designs in HIC most of the time. A narrative synthesis was conducted to report the results. In the preparedness and mitigation stages, there were six articles referring to four HP strategies. In the response and recovery phases, there were 10 articles referring to an additional four HP strategies. HP plays a role in regaining a sense of control after disaster through: engaging victims of disaster in group decisions (including children), collaboration and networking, recognition of local strengths and assets, conducting community needs assessments, respecting local knowledge, training local resources as part of an ongoing system and use of pre-existing community focal points or organizations as trusted locations for community services and reconnections. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Organizational pressures and mitigating strategies in small commercial aviation: findings from Alaska.

PubMed

Bearman, Chris; Paletz, Susannah B F; Orasanu, Judith; Brooks, Benjamin P

2009-12-01

Recent attention has focused on the way in which organizational factors can erode safety in aviation, particularly in regions that have a high accident rate, such as Alaska. The present study builds on this work by examining the direct and indirect pressures that can be exerted on pilots by Alaskan operators. In addition, the paper examines ways in which organizations and individuals manage the effects of pressure. Using the critical incident method to uncover situations where the pilot's skills had been challenged, 28 pilots who flew in Alaska were interviewed. A bottom-up qualitative analysis revealed a range of organizational pressures and mitigating strategies. Pilots in Alaska encountered both implicit and explicit norms and expectations to fly in marginal conditions. Pressure also arose from pilots' awareness of the need for their company to make money and from perceived job competition. Some Alaskan operators were able to mitigate the effects of pressure on their pilots and some pilots reported mitigating pressure to fly by managing their employer's expectations and re-emphasizing safety. Organizational factors were found to be an important source of pressure for pilots and are likely to contribute to the high accident rate in Alaska. Balancing the competing demands of safety and productivity may be extremely difficult for many small operators, which places a heavy reliance on the decision making of individuals. Both the subtle pressures on individual pilots and strategies for mitigating those pressures are, therefore, extremely important to safety and productivity in small-scale commercial aviation.

A review of proton exchange membrane water electrolysis on degradation mechanisms and mitigation strategies

NASA Astrophysics Data System (ADS)

Feng, Qi; Yuan, Xiao-Zi; Liu, Gaoyang; Wei, Bing; Zhang, Zhen; Li, Hui; Wang, Haijiang

2017-10-01

Proton exchange membrane water electrolysis (PEMWE) is an advanced and effective solution to the primary energy storage technologies. A better understanding of performance and durability of PEMWE is critical for the engineers and researchers to further advance this technology for its market penetration, and for the manufacturers of PEM water electrolyzers to implement quality control procedures for the production line or on-site process monitoring/diagnosis. This paper reviews the published works on performance degradations and mitigation strategies for PEMWE. Sources of degradation for individual components are introduced. With degradation causes discussed and degradation mechanisms examined, the review emphasizes on feasible strategies to mitigate the components degradation. To avoid lengthy real lifetime degradation tests and their high costs, the importance of accelerated stress tests and protocols is highlighted for various components. In the end, R&D directions are proposed to move the PEMWE technology forward to become a key element in future energy scenarios.

A day in the life of a volunteer incident commander: errors, pressures and mitigating strategies.

PubMed

Bearman, Christopher; Bremner, Peter A

2013-05-01

To meet an identified gap in the literature this paper investigates the tasks that a volunteer incident commander needs to carry out during an incident, the errors that can be made and the way that errors are managed. In addition, pressure from goal seduction and situation aversion were also examined. Volunteer incident commanders participated in a two-part interview consisting of a critical decision method interview and discussions about a hierarchical task analysis constructed by the authors. A SHERPA analysis was conducted to further identify potential errors. The results identified the key tasks, errors with extreme risk, pressures from strong situations and mitigating strategies for errors and pressures. The errors and pressures provide a basic set of issues that need to be managed by both volunteer incident commanders and fire agencies. The mitigating strategies identified here suggest some ways that this can be done. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Heritage and Advanced Technology Systems Engineering Lessons Learned from NASA Space Missions

NASA Technical Reports Server (NTRS)

Barley, Bryan; Newhouse, Marilyn; Bacskay, Allen

2010-01-01

Use of heritage and new technology is necessary/enabling to implementing small, low cost missions, yet overruns decrease the ability to sustain future mission flight rates The majority of the cost growth drivers seen in the D&NF study were embedded early during formulation phase and later realized during the development and I&T phases Cost drivers can be avoided or significantly decreased by project management and SE emphasis on early identification of risks and realistic analyses SE processes that emphasize an assessment of technology within the mission system to identify technical issues in the design or operational use of the technology. Realistic assessment of new and heritage spacecraft technology assumptions , identification of risks and mitigation strategies. Realistic estimates of effort required to inherit existing or qualify new technology, identification of risks to estimates and develop mitigation strategies. Allocation of project reserves for risk-based mitigation strategies of each individual area of heritage or new technology. Careful tailoring of inheritance processes to ensure due diligence.

Nonpharmaceutical Influenza Mitigation Strategies, US Communities, 1918–1920 Pandemic1

PubMed Central

Stern, Alexandra M.; Navarro, J. Alexander; Michalsen, Joseph R.; Monto, Arnold S.; DiGiovanni, Cleto

2006-01-01

We studied nonpharmaceutical interventions used to mitigate the second, and most deadly, wave of the 1918–1920 influenza pandemic in the United States. We conclude that several small communities implemented potentially successful attempts at preventing the introduction of influenza. PMID:17326953

From Vegetated Ditches to Rice Fields: Thinking Outside the Box for Pesticide Mitigation

USDA-ARS?s Scientific Manuscript database

Innovative mitigation strategies are necessary to address pesticide contamination of surface waters. Since 1998, extensive research has been conducted on the ability of vegetated agricultural drainage ditches to reduce pesticide transport to aquatic receiving systems. Recently, new research has pr...

Designing advanced biochar products for maximizing greenhouse gas mitigation potential

USDA-ARS?s Scientific Manuscript database

Greenhouse gas (GHG) emissions from agricultural operations continue to increase. Carbon enriched char materials like biochar have been described as a mitigation strategy. Utilization of biochar material as a soil amendment has been demonstrated to provide potentially further soil GHG suppression du...

An Innovative Solution to NASA's NEO Impact Threat Mitigation Grand Challenge and Flight Validation Mission Architecture Development

NASA Technical Reports Server (NTRS)

Wie, Bong; Barbee, Brent W.

2015-01-01

This paper presents the results of a NASA Innovative Advanced Concept (NIAC) Phase 2 study entitled "An Innovative Solution to NASA's Near-Earth Object (NEO) Impact Threat Mitigation Grand Challenge and Flight Validation Mission Architecture Development." This NIAC Phase 2 study was conducted at the Asteroid Deflection Research Center (ADRC) of Iowa State University in 2012-2014. The study objective was to develop an innovative yet practically implementable mitigation strategy for the most probable impact threat of an asteroid or comet with short warning time (< 5 years). The mitigation strategy described in this paper is intended to optimally reduce the severity and catastrophic damage of the NEO impact event, especially when we don't have sufficient warning times for non-disruptive deflection of a hazardous NEO. This paper provides an executive summary of the NIAC Phase 2 study results. Detailed technical descriptions of the study results are provided in a separate final technical report, which can be downloaded from the ADRC website (www.adrc.iastate.edu).

The potential of exceptional climate change education on individual lifetime carbon emissions

NASA Astrophysics Data System (ADS)

Cordero, E.; Centeno, D.; Todd, A. M.

2016-12-01

Strategies to mitigate climate change often center on clean technologies such as electric vehicles and solar panels, while the mitigation potential of a quality educational experience is rarely discussed. We investigate the role of education on individual carbon emissions using case studies from an intensive one-year university general education course focused on climate science and solutions. Results from this analysis demonstrate that students who completed the university course had significantly lower carbon emissions compared to a control group. If such an educational experience could be expanded throughout the United States, we estimate that education could be as valuable a climate change mitigation method as improving the fuel efficiency of automobiles. Relatedly, we also report on a new approach to apply real-time cloud based data to track the environmental impact of students during their participation in educational climate change programs. Such a tool would help illustrate the potential of education as a viable carbon mitigation strategy.

Co-Mitigation of Ozone and PM2.5 Pollution over the Beijing-Tianjin-Hebei Region

NASA Astrophysics Data System (ADS)

Liu, J.; Xiang, S.; Yi, K.; Tao, W.

2017-12-01

With the rapid industrialization and urbanization, emissions of air pollutants in China were increasing rapidly during the past few decades, causing severe particulate matter and ozone pollution in many megacities. Facing these knotty environmental problems, China has released a series of pollution control policies to mitigate air pollution emissions and optimize energy supplement structure. Consequently, fine particulate matters (PM2.5) decrease recently. However, the concentrations of ambient ozone have been increasing, especially during summer time and over megacities. In this study, we focus on the opposite trends of ozone and PM2.5 over the Beijing-Tianjin-Hebei region. We use the Weather Research and Forecasting model coupled with Chemistry (WRF/Chem) to simulate and analyze the best emission reduction strategies, and adopt the Empirical Kinetics Modeling Approach (EKMA) to depict the influences of mitigating NOx and VOCs. We also incorporate the abatement costs for NOx and VOCs in our analysis to explore the most cost-effective mitigation strategies for both ozone and PM2.5.

Mitigating Infectious Disease Outbreaks

NASA Astrophysics Data System (ADS)

Davey, Victoria

The emergence of new, transmissible infections poses a significant threat to human populations. As the 2009 novel influenza A/H1N1 pandemic and the 2014-2015 Ebola epidemic demonstrate, we have observed the effects of rapid spread of illness in non-immune populations and experienced disturbing uncertainty about future potential for human suffering and societal disruption. Clinical and epidemiologic characteristics of a newly emerged infectious organism are usually gathered in retrospect as the outbreak evolves and affects populations. Knowledge of potential effects of outbreaks and epidemics and most importantly, mitigation at community, regional, national and global levels is needed to inform policy that will prepare and protect people. Study of possible outcomes of evolving epidemics and application of mitigation strategies is not possible in observational or experimental research designs, but computational modeling allows conduct of `virtual' experiments. Results of well-designed computer simulations can aid in the selection and implementation of strategies that limit illness and death, and maintain systems of healthcare and other critical resources that are vital to public protection. Mitigating Infectious Disease Outbreaks.

Improved representation of investment decisions in assessments of CO2 mitigation

NASA Astrophysics Data System (ADS)

Iyer, Gokul C.; Clarke, Leon E.; Edmonds, James A.; Flannery, Brian P.; Hultman, Nathan E.; McJeon, Haewon C.; Victor, David G.

2015-05-01

Assessments of emissions mitigation patterns have largely ignored the huge variation in real-world factors--in particular, institutions--that affect where, how and at what costs firms deploy capital. We investigate one such factor--how national institutions affect investment risks and thus the cost of financing. We use an integrated assessment model (IAM; ref. ) to represent the variation in investment risks across technologies and regions in the electricity generation sector--a pivotally important sector in most assessments of climate change mitigation--and compute the impact on the magnitude and distribution of mitigation costs. This modified representation of investment risks has two major effects. First, achieving an emissions mitigation goal is more expensive than it would be in a world with uniform investment risks. Second, industrialized countries mitigate more, and developing countries mitigate less. Here, we introduce a new front in the research on how real-world factors influence climate mitigation. We also suggest that institutional reforms aimed at lowering investment risks could be an important element of cost-effective climate mitigation strategies.

Space Particle Hazard Specification, Forecasting, and Mitigation

DTIC Science & Technology

2007-11-30

Automated FTP scripts permitted users to automatically update their global input parameter data set directly from the National Oceanic and...of CEASE capabilities. The angular field-of-view for CEASE is relatively large and will not allow for pitch angle resolved measurements. However... angular zones spanning 120° in the plane containing the magnetic field with an approximate 4° width in the direction perpendicular to the look-plane

A Regional Guidebook for Conducting Functional Assessments of Forested Wetlands and Riparian Areas in the Ozark Mountains Region of Arkansas

DTIC Science & Technology

2008-09-01

compensatory mitigation. However, a variety of other potential uses have been identified, including the determination of minimal effects under the Food...at http://www.epa.gov/OWOW/wetlands/science/hgm.html, outlines a strategy for developing Regional Guidebooks throughout the United States, provides...determination of compensatory mitigation, design and monitoring of mitigation, comparison of wetland management alternatives or results, determination of

A Review on Mitigation Technologies for Controlling Urban Heat Island Effect in Housing and Settlement Areas

NASA Astrophysics Data System (ADS)

Andoni, Heri; Wonorahardjo, Surjamanto

2018-05-01

Urban Heat Island (UHI) has many harm impacts to urban and human life, the examples are increased building and energy consumption, increased air pollutants emissions, compromised human comfort and health, and many more. Despite UHI phenomenon and those impacts has been realized long enough by the experts along with development of major cities in the world, but its mitigation technology has not been well developed. This paper discusses few mitigation technologies for UHI phenomenon that have been developed by experts. Some mitigation technologies such as double skin façade, shading strategies, and many more are discussed in this study, include the strengths and the weaknesses of each strategy. The focus of the study is mainly on the potential of building skin engineering in which thermal conductivity, infrared emissivity, and specific heat factors. The selected case discussed are buildings made of heavy weight materials. The result in this study reveals a potential map where thermal insulation is one potential strategy to reduce the intensity of UHI through the reduction of heat emissions of heavy building materials components. By this study, improvement of the urban life in its relation to UHI are expected to occur, especially in housing and settlements area.

Disaster mitigation action plan: Digital media on improving accountability and community relationships

NASA Astrophysics Data System (ADS)

Adila, I.; Dewi, W. W. A.; Tamitiadini, D.; Syauki, W. R.

2017-06-01

This study wants to address on how communication science is applied to Disaster Mitigation Plan. Especially, the implementation of Community Media and Development of Communication Technology that synergize to create a Disaster Mitigation Medium, which is appropriate for typology of Indonesia. Various levels of priorities that include disaster mitigation information, namely, increasing chain system of early warning systems, building evacuation, improving alertness and capacity to face a disaster, as well as minimizing disaster risk factor. Through this concept, mitigation actions plan of Tulungagung Coastal areas is expected to be applied in other regions in Indonesia by BNPB (Badan Nasional Penanggulangan Bencana). Having this strategy to be implemented based on region characteristics, it is expected that risk reduction process can be run optimally. As a result, the strategy is known as Community-Based Disaster Risk Reduction (PRBBK), which means as the organized-efforts by society for pra-, during, and post- disaster by using available resources as much as possible to prevent, reduce, avoid, and recover from the impact of disasters. Therefore, this result can be a Pilot Project for BNBP Indonesia, as a government decisive attitude for the next steps in protecting people residing in the region prone to natural disasters all over Indonesia.

Management Strategies to Facilitate Optimal Outcomes for Patients Treated with Delayed-release Dimethyl Fumarate.

PubMed

Mayer, Lori; Fink, Mary Kay; Sammarco, Carrie; Laing, Lisa

2018-04-01

Delayed-release dimethyl fumarate is an oral disease-modifying therapy that has demonstrated significant efficacy in adults with relapsing-remitting multiple sclerosis. Incidences of flushing and gastrointestinal adverse events are common in the first month after delayed-release dimethyl fumarate initiation. Our objective was to propose mitigation strategies for adverse events related to initiation of delayed-release dimethyl fumarate in the treatment of patients with multiple sclerosis. Studies of individually developed mitigation strategies and chart reviews were evaluated. Those results, as well as mitigation protocols developed at multiple sclerosis care centers, are summarized. Key steps to optimize the effectiveness of delayed-release dimethyl fumarate treatment include education prior to and at the time of delayed-release dimethyl fumarate initiation, initiation dose protocol gradually increasing to maintenance dose, dietary suggestions for co-administration with food, gastrointestinal symptom management with over-the-counter medications, flushing symptom management with aspirin, and temporary dose reduction. Using the available evidence from clinical trials and evaluations of post-marketing studies, these strategies to manage gastrointestinal and flushing symptoms can be effective and helpful to the patient when initiating delayed-release dimethyl fumarate.

Strategies to assess the validity of recommendations: a study protocol

PubMed Central

2013-01-01

Background Clinical practice guidelines (CPGs) become quickly outdated and require a periodic reassessment of evidence research to maintain their validity. However, there is little research about this topic. Our project will provide evidence for some of the most pressing questions in this field: 1) what is the average time for recommendations to become out of date?; 2) what is the comparative performance of two restricted search strategies to evaluate the need to update recommendations?; and 3) what is the feasibility of a more regular monitoring and updating strategy compared to usual practice?. In this protocol we will focus on questions one and two. Methods The CPG Development Programme of the Spanish Ministry of Health developed 14 CPGs between 2008 and 2009. We will stratify guidelines by topic and by publication year, and include one CPG by strata. We will develop a strategy to assess the validity of CPG recommendations, which includes a baseline survey of clinical experts, an update of the original exhaustive literature searches, the identification of key references (reference that trigger a potential recommendation update), and the assessment of the potential changes in each recommendation. We will run two alternative search strategies to efficiently identify important new evidence: 1) PLUS search based in McMaster Premium LiteratUre Service (PLUS) database; and 2) a Restrictive Search (ReSe) based on the least number of MeSH terms and free text words needed to locate all the references of each original recommendation. We will perform a survival analysis of recommendations using the Kaplan-Meier method and we will use the log-rank test to analyse differences between survival curves according to the topic, the purpose, the strength of recommendations and the turnover. We will retrieve key references from the exhaustive search and evaluate their presence in the PLUS and ReSe search results. Discussion Our project, using a highly structured and transparent methodology, will provide guidance of when recommendations are likely to be at risk of being out of date. We will also assess two novel restrictive search strategies which could reduce the workload without compromising rigour when CPGs developers check for the need of updating. PMID:23967896

Odor Mitigation with Tree Buffers: Swine Production Case Study

USDA-ARS?s Scientific Manuscript database

Tree buffers are a potential low cost sustainable odor mitigation strategy, but there is little to no data on their effectiveness. Odor transport is thought to occur one of two ways either directly through vapor phase transport or indirectly through sorption onto particles. Consequently, monitoring...

Earth Girl Volcano: An Interactive Casual Game about Complex Volcanic Hazards

NASA Astrophysics Data System (ADS)

Kerlow, I.

2017-12-01

Earth Girl Volcano is an interactive casual strategy game for disaster preparedness. The project is designed for mainstream audiences, particularly for children, as an engaging and fun way to learn about volcano hazards, monitoring, and mitigation strategies. The game is deceptively simple but it provides a toolbox to address practically all volcanic hazards ranging from gas and ash fall to pyroclastic flows, lava and lahars. This presentation shows the basic dynamic to explore the area, assess the risk, choose the best-suited tools and execute a mitigation strategy within the available budget. This game is a real-time simulation of a crowd evacuation that allows players to intervene before and during the disaster.

Contamination Mitigation Strategies for Long Duration Human Spaceflight Missions

NASA Technical Reports Server (NTRS)

Lewis, Ruthan; Lupisella, Mark; Bleacher, Jake; Farrell, William

2017-01-01

Contamination control issues are particularly challenging for long-term human spaceflight and are associated with the search for life, dynamic environmental conditions, human-robotic-environment interaction, sample collection and return, biological processes, waste management, long-term environmental disturbance, etc. These issues impact mission success, human health, planetary protection, and research and discovery. Mitigation and control techniques and strategies may include and integrate long-term environmental monitoring and reporting, contamination control and planetary protection protocols, habitation site design, habitat design, and surface exploration and traverse pathways and area access planning.

Overview on mitigation of acrylamide in starchy fried and baked foods.

PubMed

Baskar, G; Aiswarya, R

2018-03-23

Acrylamide in fried and baked foods causes potential toxic effect in aniamls and humans. The major challenging task lies in developing an effective strategies for acrylamide mitigation in foods without altering its basic properties. Food scientists around the world have developed various methods to mitigate the presence of acrylamide in fired food products. The mitigation techniques such as addition of additives like salts, amino acids, cations and organic acids along with blanching of foods have reduced the concentration of acrylamide. The use of secondary metabolites like polyphenols also reduces acrylamide concentration in fried food products. The other mitigation techniques such as Asparaginase pre-treatment and low-temperature air frying with chitosan were effective in mitigating the concentration of acrylamide. Combined pre-treatment process preceding with use of additives, are the latest trend in acrylamide mitigation. This article is protected by copyright. All rights reserved.

Distinguishing the opponents promotes cooperation in well-mixed populations

NASA Astrophysics Data System (ADS)

Wardil, Lucas; da Silva, Jafferson K. L.

2010-03-01

Cooperation has been widely studied when an individual strategy is adopted against all coplayers. In this context, some extra mechanisms, such as punishment, reward, memory, and network reciprocity must be introduced in order to keep cooperators alive. Here, we adopt a different point of view. We study the adoption of different strategies against different opponents instead of adoption of the same strategy against all of them. In the context of the prisoner dilemma, we consider an evolutionary process in which strategies that provide more benefits are imitated and the players replace the strategy used in one of the interactions furnishing the worst payoff. Individuals are set in a well-mixed population, so that network reciprocity effect is excluded and both synchronous and asynchronous updates are analyzed. As a consequence of the replacement rule, we show that mutual cooperation is never destroyed and the initial fraction of mutual cooperation is a lower bound for the level of cooperation. We show by simulation and mean-field analysis that (i) cooperation dominates for synchronous update and (ii) only the initial mutual cooperation is maintained for asynchronous update. As a side effect of the replacement rule, an “implicit punishment” mechanism comes up in a way that exploitations are always neutralized providing evolutionary stability for cooperation.

Thailand's Department of Agricultural Extension and Agrochemical Dependency: Perspectives on Contributing Factors and Mitigation Strategies

ERIC Educational Resources Information Center

Nelles, Wayne; Visetnoi, Supawan

2016-01-01

Purpose: This paper discusses theoretical, policy and practical issues concerning the problem of "agrochemical dependency" in Thailand, including roles that public extension services play in advocacy or mitigation of agrochemical use. Methodology/Approach: Our research aimed to better understand department of agricultural extension…

Evaluating the mitigation of greenhouse gas emissions and adaptation in dairy production.

USDA-ARS?s Scientific Manuscript database

Process-level modeling at the farm scale provides a tool for evaluating strategies for both mitigating greenhouse gas emissions and adapting to climate change. The Integrated Farm System Model (IFSM) simulates representative crop, beef or dairy farms over many years of weather to predict performance...

USDA southwest regional hub for adaptation to and mitigation of climate change

USDA-ARS?s Scientific Manuscript database

The USDA Southwest (SW) Climate Hub was created in February 2014 to develop risk adaptation and mitigation strategies for coping with climate change effects on agricultural productivity. There are seven regional hubs across the country with three subsidiary hubs. The SW Climate Hub Region is made ...

Vegetation and other development options for mitigating urban air pollution impacts

Treesearch

Richard Baldauf; David J. Nowak

2014-01-01

While air pollution control devices and programs are the primary method of reducing emissions, urban air pollution can be further mitigated through planning and design strategies, including vegetation preservation and planting, building design and development, installing roadside and near-source structures, and modifying surrounding terrain features.

Climate change and eHealth: a promising strategy for health sector mitigation and adaptation

PubMed Central

Holmner, Åsa; Rocklöv, Joacim; Ng, Nawi; Nilsson, Maria

2012-01-01

Climate change is one of today's most pressing global issues. Policies to guide mitigation and adaptation are needed to avoid the devastating impacts of climate change. The health sector is a significant contributor to greenhouse gas emissions in developed countries, and its climate impact in low-income countries is growing steadily. This paper reviews and discusses the literature regarding health sector mitigation potential, known and hypothetical co-benefits, and the potential of health information technology, such as eHealth, in climate change mitigation and adaptation. The promising role of eHealth as an adaptation strategy to reduce societal vulnerability to climate change, and the link's between mitigation and adaptation, are also discussed. The topic of environmental eHealth has gained little attention to date, despite its potential to contribute to more sustainable and green health care. A growing number of local and global initiatives on ‘green information and communication technology (ICT)’ are now mentioning eHealth as a promising technology with the potential to reduce emission rates from ICT use. However, the embracing of eHealth is slow because of limitations in technological infrastructure, capacity and political will. Further research on potential emissions reductions and co-benefits with green ICT, in terms of health outcomes and economic effectiveness, would be valuable to guide development and implementation of eHealth in health sector mitigation and adaptation policies. PMID:22679398

Climate change and eHealth: a promising strategy for health sector mitigation and adaptation.

PubMed

Holmner, Asa; Rocklöv, Joacim; Ng, Nawi; Nilsson, Maria

2012-01-01

Climate change is one of today's most pressing global issues. Policies to guide mitigation and adaptation are needed to avoid the devastating impacts of climate change. The health sector is a significant contributor to greenhouse gas emissions in developed countries, and its climate impact in low-income countries is growing steadily. This paper reviews and discusses the literature regarding health sector mitigation potential, known and hypothetical co-benefits, and the potential of health information technology, such as eHealth, in climate change mitigation and adaptation. The promising role of eHealth as an adaptation strategy to reduce societal vulnerability to climate change, and the link's between mitigation and adaptation, are also discussed. The topic of environmental eHealth has gained little attention to date, despite its potential to contribute to more sustainable and green health care. A growing number of local and global initiatives on 'green information and communication technology (ICT)' are now mentioning eHealth as a promising technology with the potential to reduce emission rates from ICT use. However, the embracing of eHealth is slow because of limitations in technological infrastructure, capacity and political will. Further research on potential emissions reductions and co-benefits with green ICT, in terms of health outcomes and economic effectiveness, would be valuable to guide development and implementation of eHealth in health sector mitigation and adaptation policies.

Quantifying the biophysical climate change mitigation potential of Canada's forest sector

NASA Astrophysics Data System (ADS)

Smyth, C. E.; Stinson, G.; Neilson, E.; Lemprière, T. C.; Hafer, M.; Rampley, G. J.; Kurz, W. A.

2014-01-01

The potential of forests and the forest sector to mitigate greenhouse gas (GHG) emissions is widely recognized, but challenging to quantify at a national scale. Forests and their carbon (C) sequestration potential are affected by management practices, where wood harvesting transfers C out of the forest into products, and subsequent regrowth allows further C sequestration. Here we determine the mitigation potential of the 2.3 × 106 km2 of Canada's managed forests from 2015 to 2050 using the Carbon Budget Model of the Canadian Forest Sector (CBM-CFS3), a harvested wood products model that estimates emissions based on product half-life decay times, and an account of emission substitution benefits from the use of wood products and bioenergy. We examine several mitigation scenarios with different assumptions about forest management activity levels relative to a base-case scenario, including improved growth from silvicultural activities, increased harvest and residue management for bioenergy, and reduced harvest for conservation. We combine forest management options with two mitigation scenarios for harvested wood product use involving an increase in either long-lived products or bioenergy uses. Results demonstrate large differences among alternative scenarios, and we identify potential mitigation scenarios with increasing benefits to the atmosphere for many decades into the future, as well as scenarios with no net benefit over many decades. The greatest mitigation impact was achieved through a mix of strategies that varied across the country and had cumulative mitigation of 254 Tg CO2e in 2030, and 1180 Tg CO2e in 2050. We conclude that (i) national-scale forest sector mitigation options need to be assessed rigorously from a systems perspective to avoid the development of policies that deliver no net benefits to the atmosphere, (ii) a mix of strategies implemented across the country achieves the greatest mitigation impact, and (iii) because of the time delays in achieving carbon benefits for many forest-based mitigation activities, future contributions of the forest sector to climate mitigation can be maximized if implemented soon.

Using Third Party Data to Update a Reference Dataset in a Quality Evaluation Service

NASA Astrophysics Data System (ADS)

Xavier, E. M. A.; Ariza-López, F. J.; Ureña-Cámara, M. A.

2016-06-01

Nowadays it is easy to find many data sources for various regions around the globe. In this 'data overload' scenario there are few, if any, information available about the quality of these data sources. In order to easily provide these data quality information we presented the architecture of a web service for the automation of quality control of spatial datasets running over a Web Processing Service (WPS). For quality procedures that require an external reference dataset, like positional accuracy or completeness, the architecture permits using a reference dataset. However, this reference dataset is not ageless, since it suffers the natural time degradation inherent to geospatial features. In order to mitigate this problem we propose the Time Degradation & Updating Module which intends to apply assessed data as a tool to maintain the reference database updated. The main idea is to utilize datasets sent to the quality evaluation service as a source of 'candidate data elements' for the updating of the reference database. After the evaluation, if some elements of a candidate dataset reach a determined quality level, they can be used as input data to improve the current reference database. In this work we present the first design of the Time Degradation & Updating Module. We believe that the outcomes can be applied in the search of a full-automatic on-line quality evaluation platform.

Guideline on terminology and definitions of updating clinical guidelines: The Updating Glossary.

PubMed

Martínez García, Laura; Pardo-Hernández, Hector; Sanabria, Andrea Juliana; Alonso-Coello, Pablo; Penman, Katrina; McFarlane, Emma

2018-03-01

The Guidelines International Network (G-I-N) Updating Guidelines Working Group launched an initiative to develop a glossary (the Updating Glossary) with domains, terms, definitions, and synonyms related to updating of clinical guidelines (CGs). The steering committee developed an initial list of domains, terms, definitions, and synonyms through brainstorming and discussion. The panel members participated in three rounds of feedback to discuss, refine, and clarify the proposed terms, definitions, and synonyms. Finally, the panel members were surveyed to assess their level of agreement regarding the glossary. Eighteen terms were identified and defined: (1) continuous updating, (2) decision to update, (3) fixed updating, (4) full updating, (5) impact of the new evidence, (6) partial updating, (7) prioritization process, (8) reporting process, (9) signal for an update, (10) surveillance process, (11) time of validity, (12) timeframe, (13) tools and resources, (14) up to date, (15) update cycle, (16) update unit, (17) updated version, and (18) updating strategy. Consensus was reached for all terms, definitions, and synonyms (median agreement scores ≥ 6); except for one term. The G-I-N Updating Guidelines Working Group assembled the Updating Glossary to facilitate and improve the knowledge exchange among CGs developers, researchers, and users. Copyright © 2017 Elsevier Inc. All rights reserved.

Aspiration dynamics of multi-player games in finite populations

PubMed Central

Du, Jinming; Wu, Bin; Altrock, Philipp M.; Wang, Long

2014-01-01

On studying strategy update rules in the framework of evolutionary game theory, one can differentiate between imitation processes and aspiration-driven dynamics. In the former case, individuals imitate the strategy of a more successful peer. In the latter case, individuals adjust their strategies based on a comparison of their pay-offs from the evolutionary game to a value they aspire, called the level of aspiration. Unlike imitation processes of pairwise comparison, aspiration-driven updates do not require additional information about the strategic environment and can thus be interpreted as being more spontaneous. Recent work has mainly focused on understanding how aspiration dynamics alter the evolutionary outcome in structured populations. However, the baseline case for understanding strategy selection is the well-mixed population case, which is still lacking sufficient understanding. We explore how aspiration-driven strategy-update dynamics under imperfect rationality influence the average abundance of a strategy in multi-player evolutionary games with two strategies. We analytically derive a condition under which a strategy is more abundant than the other in the weak selection limiting case. This approach has a long-standing history in evolutionary games and is mostly applied for its mathematical approachability. Hence, we also explore strong selection numerically, which shows that our weak selection condition is a robust predictor of the average abundance of a strategy. The condition turns out to differ from that of a wide class of imitation dynamics, as long as the game is not dyadic. Therefore, a strategy favoured under imitation dynamics can be disfavoured under aspiration dynamics. This does not require any population structure, and thus highlights the intrinsic difference between imitation and aspiration dynamics. PMID:24598208

Aspiration dynamics of multi-player games in finite populations.

PubMed

Du, Jinming; Wu, Bin; Altrock, Philipp M; Wang, Long

2014-05-06

On studying strategy update rules in the framework of evolutionary game theory, one can differentiate between imitation processes and aspiration-driven dynamics. In the former case, individuals imitate the strategy of a more successful peer. In the latter case, individuals adjust their strategies based on a comparison of their pay-offs from the evolutionary game to a value they aspire, called the level of aspiration. Unlike imitation processes of pairwise comparison, aspiration-driven updates do not require additional information about the strategic environment and can thus be interpreted as being more spontaneous. Recent work has mainly focused on understanding how aspiration dynamics alter the evolutionary outcome in structured populations. However, the baseline case for understanding strategy selection is the well-mixed population case, which is still lacking sufficient understanding. We explore how aspiration-driven strategy-update dynamics under imperfect rationality influence the average abundance of a strategy in multi-player evolutionary games with two strategies. We analytically derive a condition under which a strategy is more abundant than the other in the weak selection limiting case. This approach has a long-standing history in evolutionary games and is mostly applied for its mathematical approachability. Hence, we also explore strong selection numerically, which shows that our weak selection condition is a robust predictor of the average abundance of a strategy. The condition turns out to differ from that of a wide class of imitation dynamics, as long as the game is not dyadic. Therefore, a strategy favoured under imitation dynamics can be disfavoured under aspiration dynamics. This does not require any population structure, and thus highlights the intrinsic difference between imitation and aspiration dynamics.

2011 National Drug Control Strategy. Executive Summary

ERIC Educational Resources Information Center

Office of National Drug Control Policy, 2011

2011-01-01

In May of 2010, President Obama released the Administration's inaugural "National Drug Control Strategy", a comprehensive approach to combat the public health and safety consequences posed by drug use. Now, a year later, the Administration is releasing its update building upon that initial "Strategy". The "Strategy" establishes ambitious goals to…

Effectiveness and Cost-Effectiveness of Expanded Antiviral Prophylaxis and Adjuvanted Vaccination Strategies for the Next Influenza Pandemic

PubMed Central

Khazeni, Nayer; Hutton, David W; Garber, Alan M; Owens, Douglas K

2011-01-01

Background The pandemic potential of the influenza A (H5N1) virus is among the greatest public health concerns of the 21st century. Objective To determine the effectiveness and cost-effectiveness of alternative pandemic mitigation and response strategies. Design Compartmental epidemic model in conjunction with a Markov model of disease progression. Data Sources Literature and expert opinion. Target Population Residents of a U.S. metropolitan city. Time Horizon Lifetime. Perspective Societal. Interventions One mitigation strategy used non-pharmaceutical interventions, vaccination, and antiviral pharmacotherapy in quantities similar to those available currently in the U.S. stockpile. The second and third strategies used expanded supplies of either antivirals (expanded antiviral prophylaxis strategy) or adjuvanted vaccine (expanded vaccination strategy) in addition to non-pharmaceutical interventions. Outcome Measures Infections and deaths averted, costs, quality-adjusted life-years (QALYs), and incremental cost-effectiveness. Results of Base Case Analysis The stockpiled strategy averted 44% of infections and deaths, gaining 258,342 QALYs at $8,907 per QALY gained relative to no intervention. Expanded antiviral prophylaxis delayed the pandemic, averting 48% of infections and deaths, and gaining 282,329 QALYs, with a less favorable cost-effectiveness ratio than adjuvanted vaccination. Adjuvanted vaccination was the most effective strategy and was cost-effective, averting 68% of infections and deaths, and gaining 404,030 QALYs at $10,844 per QALY gained relative to stockpiled strategy. Results of Sensitivity Analysis Over a wide range of assumptions, the incremental cost-effectiveness ratio of the expanded adjuvanted vaccination strategy was less than $50,000 per QALY gained. Limitations Large groups and frequent contacts may spread the virus more rapidly. The model is not designed to target interventions to specific groups. Conclusions Expanded adjuvanted vaccination is an effective and cost-effective mitigation strategy for an influenza A (H5N1) pandemic. Expanded antiviral prophylaxis can be beneficial in delaying the pandemic while additional strategies are implemented. PMID:20008760

Between universalism and relativism: a conceptual exploration of problems in formulating and applying international biomedical ethical guidelines

PubMed Central

Tangwa, G

2004-01-01

In this paper, the author attempts to explore some of the problems connected with the formulation and application of international biomedical ethical guidelines, with particular reference to Africa. Recent attempts at revising and updating some international medical ethical guidelines have been bedevilled by intractable controversies and wrangling regarding both the content and formulation. From the vantage position of relative familiarity with both African and Western contexts, and the privilege of having been involved in the revision and updating of one of the international ethical guidelines, the author reflects broadly on these issues and attempts prescribing an approach from both the theoretical and practical angles liable to mitigate, if not completely eliminate, some of the problems and difficulties. PMID:14872078

Learning Rate Updating Methods Applied to Adaptive Fuzzy Equalizers for Broadband Power Line Communications

NASA Astrophysics Data System (ADS)

Ribeiro, Moisés V.

2004-12-01

This paper introduces adaptive fuzzy equalizers with variable step size for broadband power line (PL) communications. Based on delta-bar-delta and local Lipschitz estimation updating rules, feedforward, and decision feedback approaches, we propose singleton and nonsingleton fuzzy equalizers with variable step size to cope with the intersymbol interference (ISI) effects of PL channels and the hardness of the impulse noises generated by appliances and nonlinear loads connected to low-voltage power grids. The computed results show that the convergence rates of the proposed equalizers are higher than the ones attained by the traditional adaptive fuzzy equalizers introduced by J. M. Mendel and his students. Additionally, some interesting BER curves reveal that the proposed techniques are efficient for mitigating the above-mentioned impairments.

Working Memory Updating Training Improves Mathematics Performance in Middle School Students With Learning Difficulties.

PubMed

Zhang, Hongxia; Chang, Lei; Chen, Xiaoying; Ma, Liang; Zhou, Renlai

2018-01-01

Working memory (WM) deficit is considered the key cause of learning difficulties (LDs). Studies have shown that WM is plastic and thus can be improved through training. This positive effect is transferable to fluid intelligence and academic performance. This study investigated whether WM updating ability and academic performance in children with LDs could be improved through WM updating training and explored the effects of this training on the children's brain activity. We used a running memory task lasting approximately 40 min per day for 28 days to train a group of 23 children with LDs (TLDs group). We also selected two control groups of 22 children with LDs (CLDs group) and 20 children without LDs (normal control [NC] group). The behavioral results of a pretest indicated that WM updating ability and academic performance in the TLDs and CLDs groups were significantly lower than those in the NC group before training. Compared with the CLDs group, the TLDs group exhibited significant performance improvement in a 2-back WM task, as well as in mathematical ability. Event-related potentials (ERPs) results suggested that the amplitudes of N160 (representative of visual recognition) and P300 (representative of updating processing, which is a valid index for updating WM) in the TLDs and CLDs groups were markedly lower than those in the NC group before training. In the TLDs group, these two components increased considerably after training, approaching levels similar to those in the NC group. The results of this study suggest that WM updating training can improve WM updating ability in children with LDs and the training effect can transfer to mathematical performance in such children. Furthermore, the participants' brain activity levels can exhibit positive changes. This article provides experimental evidence that WM updating training could mitigate the symptoms of LDs to a certain degree.

Comprehensive Nuclear-Test-Ban Treaty: Updated ’Safeguards’ and Net Assessments

DTIC Science & Technology

2009-06-03

measures that this nation can take unilaterally within the treaty to protect its nuclear security. To compensate for “disadvantages and risk” they...and strategic forces, and could be augmented with implementation measures . While Safeguards may be part of a future CTBT debate, both supporters and...A second path involves efforts to alter the net assessment through measures intended to mitigate perceived risks of the treaty. This path has been

From the Laboratory to the Field: Updating Capacity Building in Medical Entomology.

PubMed

Almeida, Antonio Paulo Gouveia; Fouque, Florence; Launois, Pascal; Sousa, Carla A; Silveira, Henrique

2017-09-01

Training and innovation in the field of medical entomology are essential to mitigate the burden of vector-borne diseases globally. However, there is a shortage of medical entomologists worldwide, and there are large discrepancies in capacity building in this field. In this article, we discuss the current situation, what is needed from the medical entomologist of today, and how we can bridge this gap. Copyright © 2017. Published by Elsevier Ltd.

Cloud computing in pharmaceutical R&D: business risks and mitigations.

PubMed

Geiger, Karl

2010-05-01

Cloud computing provides information processing power and business services, delivering these services over the Internet from centrally hosted locations. Major technology corporations aim to supply these services to every sector of the economy. Deploying business processes 'in the cloud' requires special attention to the regulatory and business risks assumed when running on both hardware and software that are outside the direct control of a company. The identification of risks at the correct service level allows a good mitigation strategy to be selected. The pharmaceutical industry can take advantage of existing risk management strategies that have already been tested in the finance and electronic commerce sectors. In this review, the business risks associated with the use of cloud computing are discussed, and mitigations achieved through knowledge from securing services for electronic commerce and from good IT practice are highlighted.

Exploring Post-Treatment Reversion of Antimicrobial Resistance in Enteric Bacteria of Food Animals as a Resistance Mitigation Strategy.

PubMed

Volkova, Victoriya V; KuKanich, Butch; Riviere, Jim E

2016-11-01

Antimicrobial drug use in food animals is associated with an elevation in relative abundance of bacteria resistant to the drug among the animal enteric bacteria. Some of these bacteria are potential foodborne pathogens. Evidence suggests that at least in the enteric nontype-specific Escherichia coli, after treatment the resistance abundance reverts to the background pre-treatment levels, without further interventions. We hypothesize that it is possible to define the distribution of the time period after treatment within which resistance to the administered drug, and possibly other drugs in case of coselection, in fecal bacteria of the treated animals returns to the background pre-treatment levels. Furthermore, it is possible that a novel resistance mitigation strategy for microbiological food safety could be developed based on this resistance reversion phenomenon. The strategy would be conceptually similar to existing antimicrobial drug withdrawal periods, which is a well-established and accepted mitigation strategy for avoiding violative drug residues in the edible products from the treated animals. For developing resistance-relevant withdrawals, a mathematical framework can be used to join the necessary pharmacological, microbiological, and animal production components to project the distributions of the post-treatment resistance reversion periods in the production animal populations for major antimicrobial drug classes in use. The framework can also help guide design of empirical studies into the resistance-relevant withdrawal periods and development of mitigation approaches to reduce the treatment-associated elevation of resistance in animal enteric bacteria. We outline this framework, schematically and through exemplar equations, and how its components could be formulated.

Imitate or innovate: Competition of strategy updating attitudes in spatial social dilemma games

NASA Astrophysics Data System (ADS)

Danku, Zsuzsa; Wang, Zhen; Szolnoki, Attila

2018-01-01

Evolution is based on the assumption that competing players update their strategies to increase their individual payoffs. However, while the applied updating method can be different, most of previous works proposed uniform models where players use identical way to revise their strategies. In this work we explore how imitation-based or learning attitude and innovation-based or myopic best-response attitude compete for space in a complex model where both attitudes are available. In the absence of additional cost the best response trait practically dominates the whole snow-drift game parameter space which is in agreement with the average payoff difference of basic models. When additional cost is involved then the imitation attitude can gradually invade the whole parameter space but this transition happens in a highly nontrivial way. However, the role of competing attitudes is reversed in the stag-hunt parameter space where imitation is more successful in general. Interestingly, a four-state solution can be observed for the latter game which is a consequence of an emerging cyclic dominance between possible states. These phenomena can be understood by analyzing the microscopic invasion processes, which reveals the unequal propagation velocities of strategies and attitudes.

The planetary water drama: Dual task of feeding humanity and curbing climate change

NASA Astrophysics Data System (ADS)

Rockström, J.; Falkenmark, M.; Lannerstad, M.; Karlberg, L.

2012-08-01

This paper analyses the potential conflict between resilience of the Earth system and global freshwater requirements for the dual task of carbon sequestration to reduce CO2 in the atmosphere, and food production to feed humanity by 2050. It makes an attempt to assess the order of magnitude of the increased consumptive water use involved and analyses the implications as seen from two parallel perspectives; the global perspective of human development within a “safe operating space” with regard to the definition of the Planetary Boundary for freshwater; and the social-ecological implications at the regional river basin scale in terms of sharpening water shortages and threats to aquatic ecosystems. The paper shows that the consumptive water use involved in the dual task would both transgress the proposed planetary boundary range for global consumptive freshwater use and would further exacerbate already severe river depletion, causing societal problems related to water shortage and water allocation. Thus, strategies to rely on sequestration of CO2 as a mitigation strategy must recognize the high freshwater costs involved, implying that the key climate mitigation strategy must be to reduce emissions. The paper finally highlights the need to analyze both water and carbon tradeoffs from anticipated large scale biofuel production climate change mitigation strategy, to reveal gains and impact of this in contrast to carbon sequestration strategies.

Comparative Analysis of Supply Risk-Mitigation Strategies for Critical Byproduct Minerals: A Case Study of Tellurium.

PubMed

Bustamante, Michele L; Gaustad, Gabrielle; Alonso, Elisa

2018-01-02

Materials criticality assessment is a screening framework increasingly applied to identify materials of importance that face scarcity risks. Although these assessments highlight materials for the implicit purpose of informing future action, the aggregated nature of their findings make them difficult to use for guidance in developing nuanced mitigation strategy and policy response. As a first step in the selection of mitigation strategies, the present work proposes a modeling framework and accompanying set of metrics to directly compare strategies by measuring effectiveness of risk reduction as a function of the features of projected supply demand balance over time. The work focuses on byproduct materials, whose criticality is particularly important to understand because their supplies are inherently less responsive to market balancing forces, i.e., price feedbacks. Tellurium, a byproduct of copper refining, which is critical to solar photovoltaics, is chosen as a case study, and three commonly discussed byproduct-relevant strategies are selected: dematerialization of end-use product, byproduct yield improvement, and end-of-life recycling rate improvement. Results suggest that dematerialization will be nearly twice as effective at reducing supply risk as the next best option, yield improvement. Finally, due to its infrequent use at present and its dependence upon long product lifespans, recycling end-of-life products is expected to be the least effective option despite potentially offering other benefits (e.g., cost savings and environmental impact reduction).

75 FR 38850 - NNI Strategic Plan 2010; Request for Information

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

... implements strategies that maximize the economic benefits of its investments in nanotechnology, based on... innovation strategy, NNI member agencies have identified areas ripe for significant advances through closer... human health, resulting in better risk assessment and risk mitigation strategies. Each center works as a...

Greenhouse gas emissions reduction in different economic sectors: Mitigation measures, health co-benefits, knowledge gaps, and policy implications.

PubMed

Gao, Jinghong; Hou, Hongli; Zhai, Yunkai; Woodward, Alistair; Vardoulakis, Sotiris; Kovats, Sari; Wilkinson, Paul; Li, Liping; Song, Xiaoqin; Xu, Lei; Meng, Bohan; Liu, Xiaobo; Wang, Jun; Zhao, Jie; Liu, Qiyong

2018-09-01

To date, greenhouse gas (GHG) emissions, mitigation strategies and the accompanying health co-benefits in different economic sectors have not been fully investigated. The purpose of this paper is to review comprehensively the evidence on GHG mitigation measures and the related health co-benefits, identify knowledge gaps, and provide recommendations to promote further development and implementation of climate change response policies. Evidence on GHG emissions, abatement measures and related health co-benefits has been observed at regional, national and global levels, involving both low- and high-income societies. GHG mitigation actions have mainly been taken in five sectors: energy generation, transport, food and agriculture, household and industry, consistent with the main sources of GHG emissions. GHGs and air pollutants to a large extent stem from the same sources and are inseparable in terms of their atmospheric evolution and effects on ecosystem; thus, GHG reductions are usually, although not always, estimated to have cost effective co-benefits for public health. Some integrated mitigation strategies involving multiple sectors, which tend to create greater health benefits. The pros and cons of different mitigation measures, issues with existing knowledge, priorities for research, and potential policy implications were also discussed. Findings from this study can play a role not only in motivating large GHG emitters to make decisive changes in GHG emissions, but also in facilitating cooperation at international, national and regional levels, to promote GHG mitigation policies that protect public health from climate change and air pollution simultaneously. Copyright © 2018 Elsevier Ltd. All rights reserved.

Reactions to children's transgressions in at-risk caregivers: does mitigating information, type of transgression, or caregiver directive matter?

PubMed

Irwin, Lauren M; Skowronski, John J; Crouch, Julie L; Milner, Joel S; Zengel, Bettina

2014-05-01

This study examined whether caregivers who exhibit high risk for child physical abuse differ from low-risk caregivers in reactions to transgressing children. Caregivers read vignettes describing child transgressions. These vignettes varied in: (a) the type of transgression described (moral, conventional, personal), (b) presentation of transgression-mitigating information (present, absent), and (c) whether a directive to avoid the transgression was in the vignette (yes, no). After reading each vignette, caregivers provided ratings reflecting their: (a) perceptions of transgression wrongness, (b) internal attributions about the transgressing child, (c) perceptions of the transgressing child's hostile intent, (d) own expected negative post-transgression affect, and (e) perceived likelihood of responding to the transgression with discipline that displayed power assertion and/or induction. For moral transgressions (cruelty, dishonesty, hostility, or greed), mitigating information reduced caregiver expectations that they would feel negative affect and, subsequent to the transgression, use disciplinary strategies that display power assertion. These mitigating effects were smaller among at-risk caregivers than among low-risk caregivers. Moreover, when transgressions disobeyed a directive, among low-risk caregivers, mitigating information reduced the expectation that responses to transgressions would include inductive disciplinary strategies, but it did not do so among at-risk caregivers. In certain circumstances, compared to low-risk caregivers, at-risk caregivers expect to be relatively unaffected by transgression-mitigating information. These results suggest that interventions that increase an at-risk caregiver's ability to properly assess and integrate mitigating information may play a role in reducing the caregiver's risk of child physical abuse. Copyright © 2013 Elsevier Ltd. All rights reserved.

Public health benefits of strategies to reduce greenhouse-gas emissions: overview and implications for policy makers.

PubMed

Haines, Andy; McMichael, Anthony J; Smith, Kirk R; Roberts, Ian; Woodcock, James; Markandya, Anil; Armstrong, Ben G; Campbell-Lendrum, Diarmid; Dangour, Alan D; Davies, Michael; Bruce, Nigel; Tonne, Cathryn; Barrett, Mark; Wilkinson, Paul

2009-12-19

This Series has examined the health implications of policies aimed at tackling climate change. Assessments of mitigation strategies in four domains-household energy, transport, food and agriculture, and electricity generation-suggest an important message: that actions to reduce greenhouse-gas emissions often, although not always, entail net benefits for health. In some cases, the potential benefits seem to be substantial. This evidence provides an additional and immediate rationale for reductions in greenhouse-gas emissions beyond that of climate change mitigation alone. Climate change is an increasing and evolving threat to the health of populations worldwide. At the same time, major public health burdens remain in many regions. Climate change therefore adds further urgency to the task of addressing international health priorities, such as the UN Millennium Development Goals. Recognition that mitigation strategies can have substantial benefits for both health and climate protection offers the possibility of policy choices that are potentially both more cost effective and socially attractive than are those that address these priorities independently. Copyright 2009 Elsevier Ltd. All rights reserved.

Hawaiian cultural influences on support for lava flow hazard mitigation measures during the January 1960 eruption of Kīlauea volcano, Kapoho, Hawai‘i

USGS Publications Warehouse

Gregg, Chris E.; Houghton, Bruce F.; Paton, Douglas; Swanson, D.A.; Lachman, R.; Bonk, W.J.

2008-01-01

On average, 72% of respondents favored the construction of earthen barriers to hold back or divert lava and protect Kapoho, but far fewer agreed with the military's use of bombs (14%) to protect Kapoho. In contrast, about one-third of respondents conditionally agreed with the use of bombs. It is suggested that local participation in the bombing strategy may explain the increased conditional acceptance of bombs as a mitigation tool, although this can not be conclusively demonstrated. Belief in Pele and being of Hawaiian ethnicity did not reduce support for the use of barriers, but did reduce support for bombs in both bombing scenarios. The disparity in levels of acceptance of barriers versus bombing and of one bombing strategy versus another suggests that historically public attitudes toward lava flow hazard mitigation strategies were complex. A modern comparative study is needed before the next damaging eruption to inform debates and decisions about whether or not to interfere with the flow of lava. Recent changes in the current eruption of Kīlauea make this a timely topic.

Analytical procedures for determining the impacts of reliability mitigation strategies. [supporting datasets

DOT National Transportation Integrated Search

2012-11-30

The objective of this project was to develop technical relationships between reliability improvement strategies and reliability performance metrics. This project defined reliability, explained the importance of travel time distributions for measuring...

Optimising import risk mitigation: anticipating the unintended consequences and competing risks of informal trade.

PubMed

Hueston, W; Travis, D; van Klink, E

2011-04-01

The effectiveness of risk mitigation may be compromised by informal trade, including illegal activities, parallel markets and extra-legal activities. While no regulatory system is 100% effective in eliminating the risk of disease transmission through animal and animal product trade, extreme risk aversion in formal import health regulations may increase informal trade, with the unintended consequence of creating additional risks outside regulatory purview. Optimal risk mitigation on a national scale requires scientifically sound yet flexible mitigation strategies that can address the competing risks of formal and informal trade. More robust risk analysis and creative engagement of nontraditional partners provide avenues for addressing informal trade.

Public health co-benefits of greenhouse gas emissions reduction: A systematic review.

PubMed

Gao, Jinghong; Kovats, Sari; Vardoulakis, Sotiris; Wilkinson, Paul; Woodward, Alistair; Li, Jing; Gu, Shaohua; Liu, Xiaobo; Wu, Haixia; Wang, Jun; Song, Xiaoqin; Zhai, Yunkai; Zhao, Jie; Liu, Qiyong

2018-06-15

Public health co-benefits from curbing climate change can make greenhouse gas (GHG) mitigation strategies more attractive and increase their implementation. The purpose of this systematic review is to summarize the evidence of these health co-benefits to improve our understanding of the mitigation measures involved, potential mechanisms, and relevant uncertainties. A comprehensive search for peer-reviewed studies published in English was conducted using the primary electronic databases. Reference lists from these articles were reviewed and manual searches were performed to supplement relevant studies. The identified records were screened based on inclusion criteria. We extracted data from the final retrieved papers using a pre-designed data extraction form and a quality assessment was conducted. The studies were heterogeneities, so meta-analysis was not possible and instead evidence was synthesized using narrative summaries. Thirty-six studies were identified. We identified GHG mitigation strategies in five domains - energy generation, transportation, food and agriculture, households, and industry and economy - which usually, although not always, bring co-benefits for public health. These health gains are likely to be multiplied by comprehensive measures that include more than one sectors. GHG mitigation strategies can bring about substantial and possibly cost-effective public health co-benefits. These findings are highly relevant to policy makers and other stakeholders since they point to the compounding value of taking concerted action against climate change and air pollution. Copyright © 2018. Published by Elsevier B.V.

A H∞/μ solution for microvibration mitigation in satellites: A case study

NASA Astrophysics Data System (ADS)

Preda, Valentin; Cieslak, Jérôme; Henry, David; Bennani, Samir; Falcoz, Alexandre

2017-07-01

The research work presented in this paper focuses on the development of a mixed active-passive microvibration mitigation solution capable of attenuating the transmitted vibrations generated by reaction wheels to a satellite structure. A representative benchmark provided by the European Space Agency (ESA) and Airbus Defence and Space, serves as a support for testing the proposed solution. The paper also covers modeling and design issues as well as a deep analysis of the solution within the H∞ / μ setting. Especially, an uncertainty modeling strategy is proposed to extract a Linear Fractional Transformation (LFT) model. Insight is naturally provided into various dynamical interactions between the plant elements such as bearing and isolator flexibility, gyroscopic effects, actuator dynamics and feedback-loop delays. The design of the mitigation solution is formulated into the H∞ / μ framework leading to a robust H∞ control strategy capable of achieving exemplary active attenuation performance across a wide range of reaction wheel speeds. A systematic analysis procedure based on the structured singular value μ is used to assess and demonstrate the robust stability and robust performance of the microvibration mitigation strategy. The proposed analysis method is also shown to be a powerful and reliable solution to identify worst-case scenarios without relying on traditional Monte Carlo campaigns. Time domain simulations based on a nonlinear high-fidelity industrial simulator are included as a validation step.

AMENDING SOILS WITH PHOSPHATE AS MEANS TO MITIGATE SOIL LEAD HAZARD: A CRITICAL REVIEW OF THE STATE OF THE SCIENCE

EPA Science Inventory

Ingested soil and surface dust may be important contributors to elevated blood lead (Pb) levels in children exposed to Pb contaminated environments. Mitigation strategies have typically focused on excavation and removal of the contaminated soil. However, this is not always feas...

Reducing Radon in Schools: A Team Approach.

ERIC Educational Resources Information Center

Ligman, Bryan K.; Fisher, Eugene J.

This document presents the process of radon diagnostics and mitigation in schools to help educators determine the best way to reduce elevated radon levels found in a school. The guidebook is designed to guide school leaders through the process of measuring radon levels, selecting the best mitigation strategy, and directing the efforts of a…

A wildfire risk assessment framework for land and resource management

Treesearch

Joe H. Scott; Matthew P. Thompson; David E. Calkin

2013-01-01

Wildfires can result in significant, long-lasting impacts to ecological, social, and economic systems. It is necessary, therefore, to identify and understand the risks posed by wildland fire, and to develop cost-effective mitigation strategies accordingly. This report presents a general framework with which to assess wildfire risk and explore mitigation options, and...

Climate-Change Science and Policy: What Do We Know? What Should We Do

DTIC Science & Technology

2010-09-06

These briefing charts discuss climate change science and policy including: the essence of the challenge, five myths and their refutations, climate ... change risks and impact going forward, available options, how much mitigation, how soon?, mitigation supply curve and its implications, and the Obama Administration’s strategy.

Mitigating Higher Ed Cyber Attacks

ERIC Educational Resources Information Center

Rogers, Gary; Ashford, Tina

2015-01-01

In this presentation we will discuss the many and varied cyber attacks that have recently occurred in the higher ed community. We will discuss the perpetrators, the victims, the impact and how these institutions have evolved to meet this threat. Mitigation techniques and defense strategies will be covered as will a discussion of effective security…

Forest management for mitigation and adaptation: insights from long-term silvicultural experiments

Treesearch

Anthony W. D' Amato; John B. Bradford; Shawn Fraver; Brian J. Palik

2011-01-01

Developing management strategies for addressing global climate change has become an increasingly important issue influencing forest management around the globe. Currently, management approaches are being proposed that intend to (1) mitigate climate change by enhancing forest carbon stores and (2) foster adaptation by maintaining compositionally and structurally complex...

Strategies, Protections and Mitigations for Electric Grid from Electromagnetic Pulse Effects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Foster, Rita Ann; Frickey, Steven Jay

2016-01-01

The mission of DOE’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electricity delivery system, enhance the security and reliability of America’s energy infrastructure and facilitate recovery from disruptions to the energy supply. One of the threats OE is concerned about is a high-altitude electro-magnetic pulse (HEMP) from a nuclear explosion and eletro-magnetic pulse (EMP) or E1 pulse can be generated by EMP weapons. DOE-OE provides federal leadership and technical guidance in addressing electric grid issues. The Idaho National Laboratory (INL) was chosen to conduct the EMP study for DOE-OE due tomore » its capabilities and experience in setting up EMP experiments on the electric grid and conducting vulnerability assessments and developing innovative technology to increase infrastructure resiliency. This report identifies known impacts to EMP threats, known mitigations and effectiveness of mitigations, potential cost of mitigation, areas for government and private partnerships in protecting the electric grid to EMP, and identifying gaps in our knowledge and protection strategies.« less

Considering WTO law in the design of climate change regimes beyond Kyoto

NASA Astrophysics Data System (ADS)

Gaines, Sanford E.

2009-11-01

This article describes the most important provisions of World Trade Organization (WTO) agreements that should be considered in designing laws and regulations under likely post-Kyoto climate change mitigation regimes. The Kyoto Protocol and the expected post-Kyoto international climate agreement depend on national measures to implement market-based mitigation measures. This market strategy promotes international exchanges of goods, investments, and services such as cross-border trading of credits for emissions reductions and transnational financing for projects that avoid emissions through the Clean Development Mechanism. Moreover, the United States and other countries, concerned over "leakage" of greenhouse gas (GHG) emissions through relocation of industry to other countries coupled with political worry over manufacturing competitiveness, have proposed national climate legislation containing border adjustments on imported goods or implicit subsidies for national producers, raising additional WTO considerations. The article assesses the likely effectiveness of such trade-related measures in achieving climate change mitigation goals and the potential trade policy infringements and trade distortions that they might bring about. Alternative strategies for achieving GHG mitigation goals in closer conformity with WTO law and policy will be suggested.

Nitrogen rate strategies for reducing yield-scaled nitrous oxide emissions in maize

NASA Astrophysics Data System (ADS)

Zhao, Xu; Nafziger, Emerson D.; Pittelkow, Cameron M.

2017-12-01

Mitigating nitrogen (N) losses from agriculture without negatively impacting crop productivity is a pressing environmental and economic challenge. Reductions in N fertilizer rate are often highlighted as a solution, yet the degree to which crop yields and economic returns may be impacted at the field-level remains unclear, in part due to limited data availability. Farmers are risk averse and potential yield losses may limit the success of voluntary N loss mitigation protocols, thus understanding field-level yield tradeoffs is critical to inform policy development. Using a case study of soil N2O mitigation in the US Midwest, we conducted an ex-post assessment of two economic and two environmental N rate reduction strategies to identify promising practices for maintaining maize yields and economic returns while reducing N2O emissions per unit yield (i.e. yield-scaled emissions) compared to an assumed baseline N input level. Maize yield response data from 201 on-farm N rate experiments were combined with an empirical equation predicting N2O emissions as a function of N rate. Results indicate that the economic strategy aimed at maximizing returns to N (MRTN) led to moderate but consistent reductions in yield-scaled N2O emissions with small negative impacts on yield and slight increases in median returns. The economic optimum N rate strategy reduced yield-scaled N2O emissions in 75% of cases but increased them otherwise, challenging the assumption that this strategy will automatically reduce environmental impacts per unit production. Both environmental strategies, one designed to increase N recovery efficiency and one to balance N inputs with grain N removal, further reduced yield-scaled N2O emissions but were also associated with negative yield penalties and decreased returns. These results highlight the inherent tension between achieving agronomic and economic goals while reducing environmental impacts which is often overlooked in policy discussions. To enable the development of more scalable environmental N loss mitigation strategies, yield tradeoffs occurring at the critical point of adoption (i.e. the farm-level) should be considered.

Lunar Dust: Characterization and Mitigation

NASA Technical Reports Server (NTRS)

Hyatt. Mark J.; Feighery, John

2007-01-01

Lunar dust is a ubiquitous phenomenon which must be explicitly addressed during upcoming human lunar exploration missions. Near term plans to revisit the moon as a stepping stone for further exploration of Mars, and beyond, places a primary emphasis on characterization and mitigation of lunar dust. Comprised of regolith particles ranging in size from tens of nanometers to microns, lunar dust is a manifestation of the complex interaction of the lunar soil with multiple mechanical, electrical, and gravitational effects. The environmental and anthropogenic factors effecting the perturbation, transport, and deposition of lunar dust must be studied in order to mitigate it's potentially harmful effects on exploration systems. The same hold true for assessing the risk it may pose for toxicological health problems if inhaled. This paper presents the current perspective and implementation of dust knowledge management and integration, and mitigation technology development activities within NASA's Exploration Technology Development Program. This work is presented within the context of the Constellation Program's Integrated Lunar Dust Management Strategy. This work further outlines the scientific basis for lunar dust behavior, it's characteristics and potential effects, and surveys several potential strategies for its control and mitigation both for lunar surface operations and within the working volumes of a lunar outpost. The paper also presents a perspective on lessons learned from Apollo and forensics engineering studies of Apollo hardware.

Planning Tools For Seismic Risk Mitigation. Rules And Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Paoli, Rosa Grazia

2008-07-08

Recently, Italian urban planning research in the field of seismic risk mitigation are renewing. In particular, it promotes strategies that integrate urban rehabilitation and aseismic objectives, and also politicizes that are directed to revitalizes urban systems, coupling physical renewal and socio-economic development.In Italy the first law concerning planning for seismic mitigation dates back 1974, the law n. 64 'Regulation for buildings with particular rules for the seismic areas' where the rules for buildings in seismic areas concerning also the local hazard. This law, in fact, forced the municipalities to acquire, during the formation of the plans, a preventive opinion ofmore » compatibility between planning conditions and geomorphology conditions of the territory. From this date the conviction that the seismic risk must be considered inside the territorial planning especially in terms of strategies of mitigation has been strengthened.The town planners have started to take an interest in seismic risk in the [80]s when the Irpinia's earthquake took place. The researches developed after this earthquake have established that the principal cause of the collapse of buildings are due to from the wrong location of urban settlements (on slopes or crowns) After Irpinia's earthquake the first researches on seismic risk mitigation, in particular on the aspects related to the hazards and to the urban vulnerability were made.« less

Performance-Based Assessment Resource Guide.

ERIC Educational Resources Information Center

Gilbert, Judith C.; Burger, Patricia

This resource guide reviews a variety of performance-based student assessment strategies, and provides examples of, and references for, the strategies. Strategies include anecdotal records, interviews, peer report and group evaluations, and portfolios. Materials in the guide include: (1) a resource guide update form for teachers; (2) department…

78 FR 23575 - National Advisory Council

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-19

... sustainable beyond 72 hours; the National Mass Care Strategy; the review and update of the National Incident... Mass Care Strategy will provide a framework to enhance coordination, pool expertise and strengthen response capacity of mass care throughout the nation. The ``Strategy'' will assist in establishing common...

Update and review of accuracy assessment techniques for remotely sensed data

NASA Technical Reports Server (NTRS)

Congalton, R. G.; Heinen, J. T.; Oderwald, R. G.

1983-01-01

Research performed in the accuracy assessment of remotely sensed data is updated and reviewed. The use of discrete multivariate analysis techniques for the assessment of error matrices, the use of computer simulation for assessing various sampling strategies, and an investigation of spatial autocorrelation techniques are examined.

[Guidance of FDA risk evaluation and mitigation strategy and enlightenment to drug risk management of post-marketing Chinese medicine].

PubMed

Li, Yuanyuan; Xie, Yanming

2011-10-01

The FDA risk evaluation and mitigation strategy (REMS) aims to drugs or biological products known or potential serious risk management. Analysis with the example of the content of the Onsolis REMS named FOCOS. Our country can be reference for the analysis of relevant experience and establish a scientific evaluation mechanism, strengthen the drug risk consciousness, promote the rational drug use, organic combined with the before-marketing and post-marketing evaluation of traditional Chinese medicine, and promote the evaluation of risk management of the drug development and improvement.

Enhancing the Global Carbon Sink: A Key Mitigation Strategy

NASA Astrophysics Data System (ADS)

Torn, M. S.

2016-12-01

Earth's terrestrial ecosystems absorb about one-third of all anthropogenic CO2 emissions from the atmosphere each year, greatly reducing the climate forcing those emissions would otherwise cause. This puts the size of the terrestrial carbon sink on par with the most aggressive climate mitigation measures proposed. Moreover, the land sink has been keeping pace with rising emissions and has roughly doubled over the past 40 years. But there is a fundamental lack of understanding of why the sink has been increasing and what its future trajectory could be. In developing climate mitigation strategies, governments have a very limited scientific basis for projecting the contributions of their domestic sinks, and yet at least 117 of the 160 COP21 signatories stated they will use the land sink in their Nationally Defined Contribution (NDC). Given its potentially critical role in reducing net emissions and the importance of UNFCCC land sinks in future mitigation scenarios, a first-principles understanding of the dynamics of the land sink is needed. For expansion of the sink, new approaches and ecologically-sound technologies are needed. Carefully conceived terrestrial carbon sequestration could have multiple environmental benefits, but a massive expansion of land carbon sinks using conventional approaches could place excessive demands on the world's land, water, and fertilizer nutrients. Meanwhile, rapid climatic change threatens to undermine or reverse the sink in many ecosystems. We need approaches to protect the large sinks that are currently assumed useful for climate mitigation. Thus we highlight the need for a new research agenda aimed at predicting, protecting, and enhancing the global carbon sink. Key aspects of this agenda include building a predictive capability founded on observations, theory and models, and developing ecological approaches and technologies that are sustainable and scalable, and potentially provide co-benefits such as healthier soils, more resilient and productive ecosystems, and more carbon-neutral bioenergy. Better scientific understanding of the sink provides more options for policy design, enables mitigation strategies that capture co-benefits, and increases the chances that global mitigation commitments will be met.

Estimating the Health Effects of Greenhouse Gas Mitigation Strategies: Addressing Parametric, Model, and Valuation Challenges

PubMed Central

Hess, Jeremy J.; Ebi, Kristie L.; Markandya, Anil; Balbus, John M.; Wilkinson, Paul; Haines, Andy; Chalabi, Zaid

2014-01-01

Background: Policy decisions regarding climate change mitigation are increasingly incorporating the beneficial and adverse health impacts of greenhouse gas emission reduction strategies. Studies of such co-benefits and co-harms involve modeling approaches requiring a range of analytic decisions that affect the model output. Objective: Our objective was to assess analytic decisions regarding model framework, structure, choice of parameters, and handling of uncertainty when modeling health co-benefits, and to make recommendations for improvements that could increase policy uptake. Methods: We describe the assumptions and analytic decisions underlying models of mitigation co-benefits, examining their effects on modeling outputs, and consider tools for quantifying uncertainty. Discussion: There is considerable variation in approaches to valuation metrics, discounting methods, uncertainty characterization and propagation, and assessment of low-probability/high-impact events. There is also variable inclusion of adverse impacts of mitigation policies, and limited extension of modeling domains to include implementation considerations. Going forward, co-benefits modeling efforts should be carried out in collaboration with policy makers; these efforts should include the full range of positive and negative impacts and critical uncertainties, as well as a range of discount rates, and should explicitly characterize uncertainty. We make recommendations to improve the rigor and consistency of modeling of health co-benefits. Conclusion: Modeling health co-benefits requires systematic consideration of the suitability of model assumptions, of what should be included and excluded from the model framework, and how uncertainty should be treated. Increased attention to these and other analytic decisions has the potential to increase the policy relevance and application of co-benefits modeling studies, potentially helping policy makers to maximize mitigation potential while simultaneously improving health. Citation: Remais JV, Hess JJ, Ebi KL, Markandya A, Balbus JM, Wilkinson P, Haines A, Chalabi Z. 2014. Estimating the health effects of greenhouse gas mitigation strategies: addressing parametric, model, and valuation challenges. Environ Health Perspect 122:447–455; http://dx.doi.org/10.1289/ehp.1306744 PMID:24583270

Bowel Retraining: Strategies for Establishing Bowel Control

MedlinePlus

... Us Search Bowel Retraining: Strategies for Establishing Bowel Control Home Bowel Retraining Details Treatment Last Updated: 29 ... help people with bowel disorders establish or reestablish control. Individuals with symptoms of inability to control bowel ...

Harnessing the Risk-Related Data Supply Chain: An Information Architecture Approach to Enriching Human System Research and Operations Knowledge

NASA Technical Reports Server (NTRS)

Buquo, Lynn; Johnson-Throop, Kathy

2010-01-01

NASA's Human Research Program (HRP) and Space Life Sciences Directorate (SLSD), not unlike many NASA organizations today, struggle with the inherent inefficiencies caused by dependencies on heterogeneous data systems and silos of data and information spread across decentralized discipline domains. The capture of operational and research-based data/information (both in-flight and ground-based) in disparate IT systems impedes the extent to which that data/information can be efficiently and securely shared, analyzed, and enriched into knowledge that directly and more rapidly supports HRP's research-focused human system risk mitigation efforts and SLSD s operationally oriented risk management efforts. As a result, an integrated effort is underway to more fully understand and document how specific sets of risk-related data/information are generated and used and in what IT systems that data/information currently resides. By mapping the risk-related data flow from raw data to useable information and knowledge (think of it as the data supply chain), HRP and SLSD are building an information architecture plan to leverage their existing, shared IT infrastructure. In addition, it is important to create a centralized structured tool to represent risks including attributes such as likelihood, consequence, contributing factors, and the evidence supporting the information in all these fields. Representing the risks in this way enables reasoning about the risks, e.g. revisiting a risk assessment when a mitigation strategy is unavailable, updating a risk assessment when new information becomes available, etc. Such a system also provides a concise way to communicate the risks both within the organization as well as with collaborators. Understanding and, hence, harnessing the human system risk-related data supply chain enhances both organizations' abilities to securely collect, integrate, and share data assets that improve human system research and operations.

Future shifts in African air quality and the resulting impacts on human health and climate: Design of efficient mitigation strategies.

NASA Astrophysics Data System (ADS)

Lacey, F.; Marais, E. A.; Wiedinmyer, C.; Coffey, E.; Pfotenhauer, D.; Henze, D. K.; Evans, M. J.; Hannigan, M.; Morris, E.; Davila, Y.; Mesenbring, E. C.

2017-12-01

Population in Africa is currently projected to double by 2050, which will have significant impacts on anthropogenic emissions and in turn the ambient air quality, especially near population centers. Recent research has also shown that the emissions factors used for global inventories are misrepresented when compared to field measurements in Africa, which leads to inaccuracies in the magnitude and spatial distribution of emissions throughout the continent. As the population in Africa increases, the combination of anthropogenic and biogenic emissions in many regions will lead to changes in atmospheric pollutant concentrations, including particulate matter (PM2.5) and ozone. Combining updated emissions estimates created using measured emissions factors reported from field studies in Africa with the Community Earth System Model (CESM2) improves predictions of the present day ambient air quality; validated based on available observations from field measurements and satellite data. We use these tools to quantify the impacts of anthropogenic emissions on both climate and human health, shown here as estimated premature deaths from chronic exposure to pollutants. Sensitivities derived from model source attribution calculations using the GEOS-Chem adjoint model are then used to examine the impacts of changes in population distribution and shifts in technology moving to the mid-21st century. With these results, we are able to identify efficient mitigation pathways that target specific regions and anthropogenic activities. These targeted control measures include shifts from traditional to modern cooking technologies, as well as other sector-specific interventions that represent feasible adoptions in Africa over the next several decades. This work provides a potential roadmap towards improved air quality to both government and non-governmental organizations as Africa transitions through this period of rapid growth.

Mainstreaming Climate Change Into Geosciences Curriculum of Tertiary Educational Systems in Ghana

NASA Astrophysics Data System (ADS)

Nyarko, B. K.

2015-12-01

The impact of Climate Change has a far-reaching implication for economies and people living in the fragile Regions of Africa analysts project that by 2020, between 75 million and 250 million people will be exposed various forms of Climate Change Stresses. Education as a key strategy identified under Agenda 21 has been incorporated into the efforts of various educational institutions as a means of mitigating climate change and enhancing sustainability. Climate Change education offers many opportunities and benefits for educators, researchers, learners, and for wider society, but there are also many challenges, which can hinder the successful mainstreaming of climate change education. The study aims at understanding barriers for Climate Change Education in selected tertiary institutions in Ghana. The study was conducted among Geoscience Departments of the 7 main public universities of Ghana and also juxtapose with the WASCAL graduate school curriculum. The transcript analysis identified issues that hinders the mainstreaming of Climate Change, these includes existing levels of knowledge and understanding of the concept of climate change, appreciating the threshold concepts, ineffective teaching of Climate Change and some Departments are slow in embracing Climate Change as a discipline. Hence to develop strategies to mainstream climate change education it is important to recognize that increasing the efficiency and delivery of Climate Change education requires greater attention and coordination of activities and updating the educators knowledge and skill's. Institutions and Educator should be encouraged to undertake co-curricula activities and finding ways to make Climate Change education practical.

Progress Toward Poliomyelitis Eradication - Nigeria, January-December 2017.

PubMed

Bolu, Omotayo; Nnadi, Chimeremma; Damisa, Eunice; Braka, Fiona; Siddique, Anisur; Archer, W Roodly; Bammeke, Philip; Banda, Richard; Higgins, Jeffrey; Edukugo, Aboyowa; Nganda, Gatei Wa; Forbi, Joseph C; Liu, Hongmei; Gidado, Saheed; Soghaier, Mohammed; Franka, Richard; Waziri, Ndadilnasiya; Burns, Cara C; Vertefeuille, John; Wiesen, Eric; Adamu, Usman

2018-03-02

Nearly three decades after the World Health Assembly launched the Global Polio Eradication Initiative in 1988, four of the six World Health Organization (WHO) regions have been certified polio-free (1). Nigeria is one of three countries, including Pakistan and Afghanistan, where wild poliovirus (WPV) transmission has never been interrupted. In September 2015, after >1 year without any reported WPV cases, Nigeria was removed from WHO's list of countries with endemic WPV transmission (2); however, during August and September 2016, four type 1 WPV (WPV1) cases were reported from Borno State, a state in northeastern Nigeria experiencing a violent insurgency (3). The Nigerian government, in collaboration with partners, launched a large-scale coordinated response to the outbreak (3). This report describes progress in polio eradication activities in Nigeria during January-December 2017 and updates previous reports (3-5). No WPV cases have been reported in Nigeria since September 2016; the latest case had onset of paralysis on August 21, 2016 (3). However, polio surveillance has not been feasible in insurgent-controlled areas of Borno State. Implementation of new strategies has helped mitigate the challenges of reaching and vaccinating children living in security-compromised areas, and other strategies are planned. Despite these initiatives, however, approximately 130,000-210,000 (28%-45%) of the estimated 469,000 eligible children living in inaccessible areas in 2016 have not been vaccinated. Sustained efforts to optimize surveillance and improve immunization coverage, especially among children in inaccessible areas, are needed.

Climate change adaptation and mitigation : state transportation, regional, and international strategies: synthesis.

DOT National Transportation Integrated Search

2012-07-24

This synthesis and literature review requested by Seth Start, Sustainable Transportation Manager, Washington State Department of Transportation, provides information on strategies other state DOTs countries, and local agencies are using to prepare...

Guidelines for deploying connected vehicle-enabled weather responsive traffic management strategies.

DOT National Transportation Integrated Search

2016-11-01

State and local Departments of Transportation (DOTs) are interested in providing effective traffic management and operations strategies to mitigate the roadway mobility and safety problems due to adverse weather. Weather Responsive Traffic Management...

Resilient Grid Operational Strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pasqualini, Donatella

Extreme weather-related disturbances, such as hurricanes, are a leading cause of grid outages historically. Although physical asset hardening is perhaps the most common way to mitigate the impacts of severe weather, operational strategies may be deployed to limit the extent of societal and economic losses associated with weather-related physical damage.1 The purpose of this study is to examine bulk power-system operational strategies that can be deployed to mitigate the impact of severe weather disruptions caused by hurricanes, thereby increasing grid resilience to maintain continuity of critical infrastructure during extreme weather. To estimate the impacts of resilient grid operational strategies, Losmore » Alamos National Laboratory (LANL) developed a framework for hurricane probabilistic risk analysis (PRA). The probabilistic nature of this framework allows us to estimate the probability distribution of likely impacts, as opposed to the worst-case impacts. The project scope does not include strategies that are not operations related, such as transmission system hardening (e.g., undergrounding, transmission tower reinforcement and substation flood protection) and solutions in the distribution network.« less

A Third-Generation Evidence Base for Human Spaceflight Risks

NASA Technical Reports Server (NTRS)

Kundrot, Craig E.; Lumpkins, Sarah; Steil, Jennifer; Pellis, Neal; Charles, John

2014-01-01

NASA's Human Research Program seeks to understand and mitigate risks to crew health and performance in exploration missions center dot HRP's evidence base consists of an Evidence Report for each HRP risk center dot Three generations of Evidence Reports 1) Review articles + Good content - Limited authorship, infrequent updates 2) Wikipedia articles + Viewed often, very open to contributions - Summary of reviews, very few contributions 3) HRP-controlled wiki articles + Incremental additions to review articles with editorial control

SMC Systems Engineering: Specialty Engineering Disciplines Framework and Descriptions. Volume 2

DTIC Science & Technology

2011-10-03

Engineering Disciplines Updale SNiEng Planning to Meet Program Objectives 1- -----:;..._- .-----------------, I Update SIW Eng T as1<s & Timing ol T asl<s...Analyses 1-Dev SNi Eng Products e.g. Assessmenls, Rills, Certs 1- ID & Manage Resources: Tools, Equip, Skills Assess Contractors’ Compian<:e to SIW Eng...Approaches to Meet SIW Ol>jeclives S1ipulale Contraclllal Risk and Actions lot Mitigations Review Contraclors’ Tech Data (Technical & Training Manuals

Optimal security investments and extreme risk.

PubMed

Mohtadi, Hamid; Agiwal, Swati

2012-08-01

In the aftermath of 9/11, concern over security increased dramatically in both the public and the private sector. Yet, no clear algorithm exists to inform firms on the amount and the timing of security investments to mitigate the impact of catastrophic risks. The goal of this article is to devise an optimum investment strategy for firms to mitigate exposure to catastrophic risks, focusing on how much to invest and when to invest. The latter question addresses the issue of whether postponing a risk mitigating decision is an optimal strategy or not. Accordingly, we develop and estimate both a one-period model and a multiperiod model within the framework of extreme value theory (EVT). We calibrate these models using probability measures for catastrophic terrorism risks associated with attacks on the food sector. We then compare our findings with the purchase of catastrophic risk insurance. © 2012 Society for Risk Analysis.

Identification and mitigation of stray laser light in the Thomson scattering system on the Madison Symmetric Torus (MST).

PubMed

Jacobson, C M; Borchardt, M T; Den Hartog, D J; Falkowski, A F; Morton, L A; Thomas, M A

2016-11-01

The Thomson scattering diagnostic on the Madison Symmetric Torus (MST) records excessive levels of stray Nd:YAG laser light. Stray light saturates the 1064 nm spectral channel in all polychromators, which prevents absolute electron density measurements via Rayleigh scattering calibration. Furthermore, stray light contaminates adjacent spectral channels for r/a ≥ 0.75, which renders the diagnostic unable to make electron temperature measurements at these radii. In situ measurements of stray light levels during a vacuum vessel vent are used to identify stray light sources and strategies for reduction of stray light levels. Numerical modeling using Zemax OpticStudio supports these measurements. The model of the vacuum vessel and diagnostic includes synthetic collection optics to enable direct comparison of measured and simulated stray light levels. Modeling produces qualitatively similar stray light distributions to MST measurements, and quantifies the mitigation effects of stray light mitigation strategies prior to implementation.

Identification and mitigation of stray laser light in the Thomson scattering system on the Madison Symmetric Torus (MST)

NASA Astrophysics Data System (ADS)

Jacobson, C. M.; Borchardt, M. T.; Den Hartog, D. J.; Falkowski, A. F.; Morton, L. A.; Thomas, M. A.

2016-11-01

The Thomson scattering diagnostic on the Madison Symmetric Torus (MST) records excessive levels of stray Nd:YAG laser light. Stray light saturates the 1064 nm spectral channel in all polychromators, which prevents absolute electron density measurements via Rayleigh scattering calibration. Furthermore, stray light contaminates adjacent spectral channels for r/a ≥ 0.75, which renders the diagnostic unable to make electron temperature measurements at these radii. In situ measurements of stray light levels during a vacuum vessel vent are used to identify stray light sources and strategies for reduction of stray light levels. Numerical modeling using Zemax OpticStudio supports these measurements. The model of the vacuum vessel and diagnostic includes synthetic collection optics to enable direct comparison of measured and simulated stray light levels. Modeling produces qualitatively similar stray light distributions to MST measurements, and quantifies the mitigation effects of stray light mitigation strategies prior to implementation.

The underappreciated potential of peatlands in global climate change mitigation strategies.

PubMed

Leifeld, J; Menichetti, L

2018-03-14

Soil carbon sequestration and avoidable emissions through peatland restoration are both strategies to tackle climate change. Here we compare their potential and environmental costs regarding nitrogen and land demand. In the event that no further areas are exploited, drained peatlands will cumulatively release 80.8 Gt carbon and 2.3 Gt nitrogen. This corresponds to a contemporary annual greenhouse gas emission of 1.91 (0.31-3.38) Gt CO 2 -eq. that could be saved with peatland restoration. Soil carbon sequestration on all agricultural land has comparable mitigation potential. However, additional nitrogen is needed to build up a similar carbon pool in organic matter of mineral soils, equivalent to 30-80% of the global fertilizer nitrogen application annually. Restoring peatlands is 3.4 times less nitrogen costly and involves a much smaller land area demand than mineral soil carbon sequestration, calling for a stronger consideration of peatland rehabilitation as a mitigation measure.

Synthesis of public water supply use in the United States: Spatio-temporal patterns and socio-economic controls

NASA Astrophysics Data System (ADS)

Sankarasubramanian, A.; Sabo, J. L.; Larson, K. L.; Seo, S. B.; Sinha, T.; Bhowmik, R.; Vidal, A. Ruhi; Kunkel, K.; Mahinthakumar, G.; Berglund, E. Z.; Kominoski, J.

2017-07-01

Recent U.S. Geological Survey water-use report suggests that increasing water-use efficiency could mitigate the supply-and-demand imbalance arising from changing climate and growing population. However, this rich data have neither analyzed to understand the underlying patterns, nor have been investigated to identify the factors contributing to this increased efficiency. A national-scale synthesis of public supply withdrawals ("withdrawals") reveals a strong North-south gradient in public supply water use with the increasing population in the South contributing to increased withdrawal. Contrastingly, a reverse South-north gradient exists in per capita withdrawals ("efficiency"), with northern states consistently improving the efficiency, while the southern states' efficiency declined. Our analyses of spatial patterns of per capita withdrawals further demonstrate that urban counties exhibit improved efficiency over rural counties. Improved efficiency is also demonstrated over high-income and well-educated counties. Given the potential implications of the findings in developing long-term water conservation measures (i.e., increasing block rates), we argue the need for frequent updates, perhaps monthly to annual, of water-use data for identifying effective strategies that control the water-use efficiency in various geographic settings under a changing climate.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klise, Katherine A.; Murray, Regan; Bynum, Michael

Water utilities are vulnerable to a wide variety of human-caused and natural disasters. These disruptive events can result in loss of water service, contaminated water, pipe breaks, and failed equipment. Furthermore, long term changes in water supply and customer demand can have a large impact on the operating conditions of the network. The ability to maintain drinking water service during and following these types of events is critical. Simulation and analysis tools can help water utilities explore how their network will respond to disruptive events and plan effective mitigation strategies. The U.S. Environmental Protection Agency and Sandia National Laboratories aremore » developing new software tools to meet this need. The Water Network Tool for Resilience (WNTR, pronounced winter) is a Python package designed to help water utilities investigate resilience of water distribution systems over a wide range of hazardous scenarios and to evaluate resilience-enhancing actions. The following documentation includes installation instructions and examples, description of software features, and software license. It is assumed that the reader is familiar with the Python Programming Language. References are included for additional background on software components. Online documentation, hosted at http://wntr.readthedocsio/, will be updated as new features are added. The online version includes API documentation and information for developers.« less

Analysis of construction accidents in Spain, 2003-2008.

PubMed

López Arquillos, Antonio; Rubio Romero, Juan Carlos; Gibb, Alistair

2012-12-01

The research objective for this paper is to obtain a new extended and updated insight to the likely causes of construction accidents in Spain, in order to identify suitable mitigating actions. The paper analyzes all construction sector accidents in Spain between 2003 and 2008. Ten variables were chosen and the influence of each variable is evaluated with respect to the severity of the accident. The descriptive analysis is based on a total of 1,163,178 accidents. Results showed that the severity of accidents was related to variables including age, CNAE (National Classification of Economic Activities) code, size of company, length of service, location of accident, day of the week, days of absence, deviation, injury, and climatic zones. According to data analyzed, a large company is not always necessarily safer than a small company in the aspect of fatal accidents, experienced workers do not have the best accident fatality rates, and accidents occurring away from the usual workplace had more severe consequences. Results obtained in this paper can be used by companies in their occupational safety strategies, and in their safety training programs. Copyright © 2012 National Safety Council and Elsevier Ltd. All rights reserved.

Validation of a Fast-Response Urban Micrometeorological Model to Assess the Performance of Urban Heat Island Mitigation Strategies

NASA Astrophysics Data System (ADS)

Nadeau, D.; Girard, P.; Overby, M.; Pardyjak, E.; Stoll, R., II; Willemsen, P.; Bailey, B.; Parlange, M. B.

2015-12-01

Urban heat islands (UHI) are a real threat in many cities worldwide and mitigation measures have become a central component of urban planning strategies. Even within a city, causes of UHI vary from one neighborhood to another, mostly due the spatial variability in surface thermal properties, building geometry, anthropogenic heat flux releases and vegetation cover. As a result, the performance of UHI mitigation measures also varies in space. Hence, there is a need to develop a tool to quantify the efficiency of UHI mitigation measures at the neighborhood scale. The objective of this ongoing study is to validate the fast-response micrometeorological model QUIC EnvSim (QES). This model can provide all information required for UHI studies with a fine spatial resolution (up to 0.5m) and short computation time. QES combines QUIC, a CFD-based wind solver and dispersion model, and EnvSim, composed of a radiation model, a land-surface model and a turbulent transport model. Here, high-resolution (1 m) simulations are run over a subset of the École Polytechnique Fédérale de Lausanne (EPFL) campus including complex buildings, various surfaces properties and vegetation. For nearly five months in 2006-07, a dense network of meteorological observations (92 weather stations over 0.1 km2) was deployed over the campus and these unique data are used here as a validation dataset. We present validation results for different test cases (e.g., sunny vs cloudy days, different incoming wind speeds and directions) and explore the effect of a few UHI mitigation strategies on the spatial distribution of near-surface air temperatures. Preliminary results suggest that QES may be a valuable tool in decision-making regarding adaptation of urban planning to UHI.

The Neurovestibular Challenges of Astronauts and Balance Patients: Some Past Countermeasures and Two Alternative Approaches to Elicitation, Assessment and Mitigation

PubMed Central

Lawson, Ben D.; Rupert, Angus H.; McGrath, Braden J.

2016-01-01

Astronauts and vestibular patients face analogous challenges to orientation function due to adaptive exogenous (weightlessness-induced) or endogenous (pathology-induced) alterations in the processing of acceleration stimuli. Given some neurovestibular similarities between these challenges, both affected groups may benefit from shared research approaches and adaptation measurement/improvement strategies. This article reviews various past strategies and introduces two plausible ground-based approaches, the first of which is a method for eliciting and assessing vestibular adaptation-induced imbalance. Second, we review a strategy for mitigating imbalance associated with vestibular pathology and fostering readaptation. In discussing the first strategy (for imbalance assessment), we review a pilot study wherein imbalance was elicited (among healthy subjects) via an adaptive challenge that caused a temporary/reversible disruption. The surrogate vestibular deficit was caused by a brief period of movement-induced adaptation to an altered (rotating) gravitoinertial frame of reference. This elicited adaptation and caused imbalance when head movements were made after reentry into the normal (non-rotating) frame of reference. We also review a strategy for fall mitigation, viz., a prototype tactile sway feedback device for aiding balance/recovery after disruptions caused by vestibular pathology. We introduce the device and review a preliminary exploration of its effectiveness in aiding clinical balance rehabilitation (discussing the implications for healthy astronauts). Both strategies reviewed in this article represent cross-disciplinary research spin-offs: the ground-based vestibular challenge and tactile cueing display were derived from aeromedical research to benefit military aviators suffering from flight simulator-relevant aftereffects or inflight spatial disorientation, respectively. These strategies merit further evaluation using clinical and astronaut populations. PMID:27920669

The Neurovestibular Challenges of Astronauts and Balance Patients: Some Past Countermeasures and Two Alternative Approaches to Elicitation, Assessment and Mitigation.

PubMed

Lawson, Ben D; Rupert, Angus H; McGrath, Braden J

2016-01-01

Astronauts and vestibular patients face analogous challenges to orientation function due to adaptive exogenous (weightlessness-induced) or endogenous (pathology-induced) alterations in the processing of acceleration stimuli. Given some neurovestibular similarities between these challenges, both affected groups may benefit from shared research approaches and adaptation measurement/improvement strategies. This article reviews various past strategies and introduces two plausible ground-based approaches, the first of which is a method for eliciting and assessing vestibular adaptation-induced imbalance. Second, we review a strategy for mitigating imbalance associated with vestibular pathology and fostering readaptation. In discussing the first strategy (for imbalance assessment), we review a pilot study wherein imbalance was elicited (among healthy subjects) via an adaptive challenge that caused a temporary/reversible disruption. The surrogate vestibular deficit was caused by a brief period of movement-induced adaptation to an altered (rotating) gravitoinertial frame of reference. This elicited adaptation and caused imbalance when head movements were made after reentry into the normal (non-rotating) frame of reference. We also review a strategy for fall mitigation, viz., a prototype tactile sway feedback device for aiding balance/recovery after disruptions caused by vestibular pathology. We introduce the device and review a preliminary exploration of its effectiveness in aiding clinical balance rehabilitation (discussing the implications for healthy astronauts). Both strategies reviewed in this article represent cross-disciplinary research spin-offs: the ground-based vestibular challenge and tactile cueing display were derived from aeromedical research to benefit military aviators suffering from flight simulator-relevant aftereffects or inflight spatial disorientation, respectively. These strategies merit further evaluation using clinical and astronaut populations.

Natural language processing and inference rules as strategies for updating problem list in an electronic health record.

PubMed

Plazzotta, Fernando; Otero, Carlos; Luna, Daniel; de Quiros, Fernan Gonzalez Bernaldo

2013-01-01

Physicians do not always keep the problem list accurate, complete and updated. To analyze natural language processing (NLP) techniques and inference rules as strategies to maintain completeness and accuracy of the problem list in EHRs. Non systematic literature review in PubMed, in the last 10 years. Strategies to maintain the EHRs problem list were analyzed in two ways: inputting and removing problems from the problem list. NLP and inference rules have acceptable performance for inputting problems into the problem list. No studies using these techniques for removing problems were published Conclusion: Both tools, NLP and inference rules have had acceptable results as tools for maintain the completeness and accuracy of the problem list.

Wildfire Mitigation and Private Lands: Managing Long-Term Vulnerabilities

Treesearch

Brian Muller; Stacey Schulte

2006-01-01

Long-term management of wildfire vulnerability requires strategies that address complex interactions between fire ecology and human settlement. In this paper, we examine the integration of wildfire mitigation and land use planning in county governments in the western U.S. This research relies on data from two sources. First, we conducted a survey of land use...

Management trade-off between aboveground carbon storage and understory plant species richness in temperate forests

Treesearch

Julia I. Burton; Adrian Ares; Deanna H. Olson; Klaus J. Puettmann

2013-01-01

Because forest ecosystems have the capacity to store large quantities of carbon (C), there is interest in managing forests to mitigate elevated CO2 concentrations and associated effects on the global climate. However, some mitigation techniques may contrast with management strategies for other goals, such as maintaining and restoring biodiversity...

Mitigating the Risk of Environmental Hazards in Mexico

DTIC Science & Technology

2011-10-28

consultant reports, country data, media reports, medical studies, government websites, environmental data, and Congressional testimony. iv... medications , immunizations, or personal protective equipment). DoD Instruction Number 6490.03, dated August 2006, states the objective is “to...complexity, with the potential for tragic medical outcomes in the absence of a risk mitigation strategy. 8 EXPOSURES DURING PAST DEPLOYMENTS

EUCOM Announces Updated Theater Strategy |

Science.gov Websites

and vision. Looking back, 2015 was undoubtedly one of the busiest years for EUCOM since the end of the fully address new challenges and their long term implications. The strategy contains new command vision

Threatened and Endangered Species Habitat Management Plan for Los Alamos National Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keller, David Charles; Hathcock, Charles Dean

Los Alamos National Laboratory’s (LANL) Threatened and Endangered Species Habitat Management Plan (HMP) fulfills a commitment made to the U.S. Department of Energy (DOE) in the “Final Environmental Impact Statement for the Dual-Axis Radiographic Hydrodynamic Test Facility Mitigation Action Plan” (DOE 1996). The HMP received concurrence from the U.S. Fish and Wildlife Service (USFWS) in 1999 (USFWS consultation numbers 2-22-98-I-336 and 2-22-95-I-108). This 2015 update retains the management guidelines from the 1999 HMP for listed species, updates some descriptive information, and adds the New Mexico Meadow Jumping Mouse (Zapus hudsonius luteus) and Yellow-billed Cuckoo (Coccyzus americanus) which were federally listedmore » in 2014 (Keller 2015: USFWS consultation number 02ENNM00- 2015-I-0538).« less

Quantifying the biophysical climate change mitigation potential of Canada's forest sector

NASA Astrophysics Data System (ADS)

Smyth, C. E.; Stinson, G.; Neilson, E.; Lemprière, T. C.; Hafer, M.; Rampley, G. J.; Kurz, W. A.

2014-07-01

The potential of forests and the forest sector to mitigate greenhouse gas (GHG) emissions is widely recognized, but challenging to quantify at a national scale. Forests and their carbon (C) sequestration potential are affected by management practices, where wood harvesting transfers C out of the forest into products, and subsequent regrowth allows further C sequestration. Here we determine the mitigation potential of the 2.3 × 106 km2 of Canada's managed forests from 2015 to 2050 using the Carbon Budget Model of the Canadian Forest Sector (CBM-CFS3), a harvested wood products (HWP) model that estimates emissions based on product half-life decay times, and an account of emission substitution benefits from the use of wood products and bioenergy. We examine several mitigation scenarios with different assumptions about forest management activity levels relative to a base case scenario, including improved growth from silvicultural activities, increased harvest and residue management for bioenergy, and reduced harvest for conservation. We combine forest management options with two mitigation scenarios for harvested wood product use involving an increase in either long-lived products or bioenergy uses. Results demonstrate large differences among alternative scenarios, and we identify potential mitigation scenarios with increasing benefits to the atmosphere for many decades into the future, as well as scenarios with no net benefit over many decades. The greatest mitigation impact was achieved through a mix of strategies that varied across the country and had cumulative mitigation of 254 Tg CO2e in 2030, and 1180 Tg CO2e in 2050. There was a trade-off between short-term and long-term goals, in that maximizing short-term emissions reduction could reduce the forest sector's ability to contribute to longer-term objectives. We conclude that (i) national-scale forest sector mitigation options need to be assessed rigorously from a systems perspective to avoid the development of policies that deliver no net benefits to the atmosphere, (ii) a mix of strategies implemented across the country achieves the greatest mitigation impact, and (iii) because of the time delays in achieving carbon benefits for many forest-based mitigation activities, future contributions of the forest sector to climate mitigation can be maximized if implemented soon.

Simulation of Urban Heat Island Mitigation Strategies in Atlanta, GA Using High-Resolution Land Use/Land Cover Data Set to Enhance Meteorological Modeling

NASA Technical Reports Server (NTRS)

Crosson, William L.; Dembek, Scott; Estes, Maurice G., Jr.; Limaye, Ashutosh S.; Lapenta, William; Quattrochi, Dale A.; Johnson, Hoyt; Khan, Maudood

2006-01-01

The specification of land use/land cover (LULC) and associated land surface parameters in meteorological models at all scales has a major influence on modeled surface energy fluxes and boundary layer states. In urban areas, accurate representation of the land surface may be even more important than in undeveloped regions due to the large heterogeneity within the urban area. Deficiencies in the characterization of the land surface related to the spatial or temporal resolution of the data, the number of LULC classes defined, the accuracy with which they are defined, or the degree of heterogeneity of the land surface properties within each class may degrade the performance of the models. In this study, an experiment was conducted to test a new high-resolution LULC data set for meteorological simulations for the Atlanta, Georgia metropolitan area using a mesoscale meteorological model and to evaluate the effects of urban heat island (UHI) mitigation strategies on modeled meteorology for 2030. Simulation results showed that use of the new LULC data set reduced a major deficiency of the land use data used previously, specifically the poor representation of urban and suburban land use. Performance of the meteorological model improved substantially, with the overall daytime cold bias reduced by over 30%. UHI mitigation strategies were projected to offset much of a predicted urban warming between 2000 and 2030. In fact, for the urban core, the cooling due to UHI mitigation strategies was slightly greater than the warming associated with urbanization over this period. For the larger metropolitan area, cooling only partially offset the projected warming trend.

Mitigating the consequences of accidents

DOT National Transportation Integrated Search

2005-08-01

If an accident occurs, effective strategies must be available to minimize the effects in terms of loss of life, injury, and property damage. The Volpe Center's work in this area is reviewed in this report. It ranges from occupant protection strategie...

Kootenai River Floodplain Ecosystem Operational Loss Assessment, Protection, Mitigation and Rehabilitation, 2007-2008 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Merz, Norm

2009-02-18

The overarching goals of the 'Kootenai River Floodplain Ecosystem Operational Loss Assessment, Protection, Mitigation and Rehabilitation' Project (BPA Project No.2002-011-00) are to: (1) assess abiotic and biotic factors (i.e., geomorphologic, hydrological, aquatic and riparian/floodplain communities) in determining a definitive composition of ecological integrity, (2) develop strategies to assess and mitigate losses of ecosystem functions, and (3) produce a regional operational loss assessment framework. To produce a scientifically defensible, repeatable, and complete assessment tool, KTOI assembled a team of top scientists in the fields of hydrology, hydraulics, ornithology, entomology, statistics, and river ecology, among other expertise. This advisory team is knownmore » as the Research Design and Review Team (RDRT). The RDRT scientists drive the review, selection, and adaptive management of the research designs to evaluate the ecologic functions lost due to the operation of federal hydropower facilities. The unique nature of this project (scientific team, newest/best science, adaptive management, assessment of ecological functions, etc.) has been to work in a dynamic RDRT process. In addition to being multidisciplinary, this model KTOI project provides a stark contrast to the sometimes inflexible process (review, re-review, budgets, etc.) of the Columbia River Basin Fish and Wildlife Program. The project RDRT is assembled annually, with subgroups meeting as needed throughout the year to address project issues, analyses, review, and interpretation. Activities of RDRT coordinated and directed the selection of research and assessment methodologies appropriate for the Kootenai River Watershed and potential for regional application in the Columbia River Basin. The entire RDRT continues to meet annually to update and discuss project progress. RDRT Subcontractors work in smaller groups throughout the year to meet project objectives. Determining the extent to which ecological systems are experiencing anthropogenic disturbance and change in structure and function is critical for long term conservation of biotic diversity in the face of changing landscapes and land use. KTOI and the RDRT propose a concept based on incorporating hydrologic, aquatic, and terrestrial components into an operations-based assessment framework to assess ecological losses as shown in Figure E-1.« less

Incentives for mitigation investment and more effective risk management: the need for public-private partnerships.

PubMed

Kunreuther, H

2001-09-14

A key question facing both well-developed industrial countries and emerging economies is how to reduce future disaster losses while still providing financial protection to victims from these events. This paper proposes a strategy for the use of cost-effective risk mitigation measures coupled with insurance and/or new capital market instruments to achieve these objectives. The mix of these measures will depend on the governance structure and the institutional arrangements in the particular country. There will always be a need for a combination of policy tools and the interaction among key interested parties from both the private and public sectors in developing a disaster management strategy. Two examples, one from US and the other from Honduras, illustrate differences between strategies that countries can adopt.

Situational Variations in Request and Apology Realization Strategies among International Postgraduate Students at Malaysian Universities

ERIC Educational Resources Information Center

Muthusamy, Paramasivam; Farashaiyan, Atieh

2016-01-01

The present study attempted to describe the request, apology, and request mitigation strategies utilized by international postgraduate students in confronting different situations. In addition, it examined the effects of the situational factors of social distance, power, and imposition on the students' choice of request and apology strategies as…

A Qualitative Analysis of the Coping Strategies of Substitute Teachers

ERIC Educational Resources Information Center

Vorell, Matthew S.

2011-01-01

This study distinguishes whether substitute teachers enact coping strategies that mitigate the source of work-related stress (problem-centered) or coping strategies that enable them to adapt to stress created by work-related stressors (avoidance-centered). The author gathered data for this analysis by conducting 37 in-depth interviews with…

IPM Use With the Deployment of a Non-High Dose Bt Pyramid and Mitigation of Resistance for Western Corn Rootworm (Diabrotica virgifera virgifera).

PubMed

Martinez, J C; Caprio, M A

2016-03-27

Recent detection of western corn rootworm resistance to Bt (Bacillus thuringiensis) corn prompted recommendations for the use of integrated pest management (IPM) with planting refuges to prolong the durability of Bt technologies. We conducted a simulation experiment exploring the effectiveness of various IPM tools at extending durability of pyramided Bt traits. Results indicate that some IPM practices have greater merits than others. Crop rotation was the most effective strategy, followed by increasing the non-Bt refuge size from 5 to 20%. Soil-applied insecticide use for Bt corn did not increase the durability compared with planting Bt with refuges alone, and both projected lower durabilities. When IPM participation with randomly selected management tools was increased at the time of Bt commercialization, durability of pyramided traits increased as well. When non-corn rootworm expressing corn was incorporated as an IPM option, the durability further increased.For corn rootworm, a local resistance phenomenon appeared immediately surrounding the resistant field (hotspot) and spread throughout the local neighborhood in six generations in absence of mitigation. Hotspot mitigation with random selection of strategies was ineffective at slowing resistance, unless crop rotation occurred immediately; regional mitigation was superior to random mitigation in the hotspot and reduced observed resistance allele frequencies in the neighborhood. As resistance alleles of mobile pests can escape hotspots, the scope of mitigation should extend beyond resistant sites. In the case of widespread resistance, regional mitigation was less effective at prolonging the life of the pyramid than IPM with Bt deployment at the time of commercialization. Published by Oxford University Press on behalf of Entomological Society of America 2016. This work is written by US Government employees and is in the public domain in the United States.

Risk evaluation and mitigation strategies: a focus on belatacept.

PubMed

Sam, Teena; Gabardi, Steven; Tichy, Eric M

2013-03-01

To review the elements and components of the risk evaluation and mitigation strategies (REMS) for the costimulation blocker belatacept and associated implications for health care providers working with transplant recipients. The MEDLINE and EMBASE databases (January 1990 to March 2012) were searched by using risk evaluation and mitigation strategies, REMS, belatacept, and organ transplant as search terms (individual organs were also searched). Retrieved articles were supplemented with analysis of information obtained from the Federal Register, the Food and Drug Administration, and the manufacturer of belatacept. REMS are risk-management strategies implemented to ensure that a product's benefits outweigh its known safety risks. Although belatacept offers a novel strategy in maintenance immunosuppression and was associated with superior renal function compared with cyclosporine in phase 2 and 3 trials, belatacept is also associated with increased risk of posttransplant lymphoproliferative disorder and central nervous system infections. The Food and Drug Administration required development of a REMS program as part of belatacept's approval process to ensure safe and appropriate use of the medication and optimization of its risk-benefit profile. Elements of the belatacept REMS include a medication guide that must be dispensed with each infusion and a communication plan. In the management of a complex population of patients, it is essential that those who care for transplant recipients, and patients, recognize the implications of potential and known risks of belatacept. The REMS program aims to facilitate careful selection and education of patients and vigilant monitoring.

A U.S. Biodefense Strategy Primer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poulin, D

2009-05-11

The anthrax mailings that followed the attacks of September 11, 2001 highlighted the need for a comprehensive national strategy to prevent, prepare for, respond to, and mitigate the effects of biological attacks. The goal of U.S. biodefense strategy is to reduce the likelihood of a future biological event, improve overall U.S. public health security, and minimize the economic and social disruption of a biological incident. Presidential communications, federal legislation, and executive agency planning documents provide the foundation for this strategy. Central to current U.S. biodefense strategy is the 2004 Homeland Security Presidential Directive (HSPD) 10, Biodefense for the 21st Century,more » which states that ''the United States will use all means necessary to prevent, protect against, and mitigate biological weapons attacks perpetrated against our homeland and our global interests.'' HSPD-10 also sets forth four pillars of U.S. biodefense: {sm_bullet} Threat awareness includes timely, accurate, and relevant intelligence, threat assessment, and the anticipation of future threats. {sm_bullet} Prevention and protection involve continuing and expanding efforts to limit access to agents, technologies, and knowledge to certain groups and countries as well as protecting critical infrastructure from the effects of biological attacks. {sm_bullet} Surveillance and detection provide early warning or recognition of biological attacks to permit a timely response and mitigation of consequences as well as attribution. {sm_bullet} Response and recovery include pre-attack planning and preparedness, capabilities to treat casualties, risk communications, physical control measures, medical countermeasures, and decontamination capabilities.« less

Establishing an In-House Wind Maintenance Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2011-12-01

Update to the 2008 guidebook titled “Establishing an In-house Wind Maintenance Program”, which was developed to support utilities in developing O&M strategies. This update includes significant contributions from utilities and other stakeholders around the country, representing all perspectives and regardless of whether or not they own wind turbines or projects.

Building Principal Pipelines: A Strategy to Strengthen Education Leadership. Update

ERIC Educational Resources Information Center

Syed, Sarosh

2015-01-01

School leadership is second only to teaching among school influences on student success, according to research. So what can a school district do to produce a large and steady supply of top-notch school principals--and support their effective supervision? This Wallace Update describes two related Wallace Foundation initiatives seeking answers to…

TOOLS FOR DETERMINING SUSTAINABLE WASTE MANAGEMENT THROUGH APPLICATION OF LIFE-CYCLE ASSESSMENT: UPDATE ON U.S. RESEARCH

EPA Science Inventory

The paper is an update on U.S. research to develop tools and information for evaluating integrated solid waste management strategies. In the past, waste management systems consisted primarily of waste collection and disposal at a local landfill. Today's municipal solid waste ma...

13 CFR 124.403 - How is a business plan updated and modified?

Code of Federal Regulations, 2010 CFR

2010-01-01

... incorporated into its business plan. The transition management strategy must describe: (1) How the Participant... business growth and promote profitable business operations after the expiration of its program term. (d... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How is a business plan updated and...

Asynchronous updates can promote the evolution of cooperation on multiplex networks

NASA Astrophysics Data System (ADS)

Allen, James M.; Hoyle, Rebecca B.

2017-04-01

We study the importance to the frequency of cooperation of the choice of updating strategies in a game played asynchronously or synchronously across layers in a multiplex network. Updating asynchronously in the public goods game leads to higher frequencies of cooperation compared to synchronous updates. How large this effect is depends on the sensitivity of the game dynamics to changes in the number of cooperators surrounding a player, with the largest effect observed when players payoffs are small. The discovery of this effect enhances understanding of cooperation on multiplex networks, and demonstrates a new way to maintain cooperation in these systems.

Pseudodynamic systems approach based on a quadratic approximation of update equations for diffuse optical tomography.

PubMed

Biswas, Samir Kumar; Kanhirodan, Rajan; Vasu, Ram Mohan; Roy, Debasish

2011-08-01

We explore a pseudodynamic form of the quadratic parameter update equation for diffuse optical tomographic reconstruction from noisy data. A few explicit and implicit strategies for obtaining the parameter updates via a semianalytical integration of the pseudodynamic equations are proposed. Despite the ill-posedness of the inverse problem associated with diffuse optical tomography, adoption of the quadratic update scheme combined with the pseudotime integration appears not only to yield higher convergence, but also a muted sensitivity to the regularization parameters, which include the pseudotime step size for integration. These observations are validated through reconstructions with both numerically generated and experimentally acquired data.

A summary of the new GINA strategy: a roadmap to asthma control

PubMed Central

Bateman, Eric D.; Becker, Allan; Boulet, Louis-Philippe; Cruz, Alvaro A.; Drazen, Jeffrey M.; Haahtela, Tari; Hurd, Suzanne S.; Inoue, Hiromasa; de Jongste, Johan C.; Lemanske, Robert F.; Levy, Mark L.; O'Byrne, Paul M.; Paggiaro, Pierluigi; Pedersen, Soren E.; Pizzichini, Emilio; Soto-Quiroz, Manuel; Szefler, Stanley J.; Wong, Gary W.K.; FitzGerald, J. Mark

2015-01-01

Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and annually updated a global strategy for asthma management and prevention that has formed the basis for many national guidelines. However, uptake of existing guidelines is poor. A major revision of the GINA report was published in 2014, and updated in 2015, reflecting an evolving understanding of heterogeneous airways disease, a broader evidence base, increasing interest in targeted treatment, and evidence about effective implementation approaches. During development of the report, the clinical utility of recommendations and strategies for their practical implementation were considered in parallel with the scientific evidence. This article provides a summary of key changes in the GINA report, and their rationale. The changes include a revised asthma definition; tools for assessing symptom control and risk factors for adverse outcomes; expanded indications for inhaled corticosteroid therapy; a framework for targeted treatment based on phenotype, modifiable risk factors, patient preference, and practical issues; optimisation of medication effectiveness by addressing inhaler technique and adherence; revised recommendations about written asthma action plans; diagnosis and initial treatment of the asthma−chronic obstructive pulmonary disease overlap syndrome; diagnosis in wheezing pre-school children; and updated strategies for adaptation and implementation of GINA recommendations. PMID:26206872

The Role of Task Understanding on Younger and Older Adults' Performance.

PubMed

Frank, David J; Touron, Dayna R

2016-12-16

Age-related performance decrements have been linked to inferior strategic choices. Strategy selection models argue that accurate task representations are necessary for choosing appropriate strategies. But no studies to date have compared task representations in younger and older adults. Metacognition research suggests age-related deficits in updating and utilizing strategy knowledge, but other research suggests age-related sparing when information can be consolidated into a coherent mental model. Study 1 validated the use of concept mapping as a tool for measuring task representation accuracy. Study 2 measured task representations before and after a complex strategic task to test for age-related decrements in task representation formation and updating. Task representation accuracy and task performance were equivalent across age groups. Better task representations were related to better performance. However, task representation scores remained fairly stable over the task with minimal evidence of updating. Our findings mirror those in the mental model literature suggesting age-related sparing of strategy use when information can be integrated into a coherent mental model. Future research should manipulate the presence of a unifying context to better evaluate this hypothesis. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Referring to the social performance promotes cooperation in spatial prisoner's dilemma games

NASA Astrophysics Data System (ADS)

Shigaki, Keizo; Tanimoto, Jun; Wang, Zhen; Kokubo, Satoshi; Hagishima, Aya; Ikegaya, Naoki

2012-09-01

We propose a new pairwise Fermi updating rule by considering a social average payoff when an agent copies a neighbor's strategy. In the update rule, a focal agent compares her payoff with the social average payoff of the same strategy that her pairwise opponent has. This concept might be justified by the fact that people reference global and, somehow, statistical information, not local information when imitating social behaviors. We presume several possible ways for the social average. Simulation results prove that the social average of some limited agents realizes more significant cooperation than that of the entire population.

Beyond pairwise strategy updating in the prisoner's dilemma game

NASA Astrophysics Data System (ADS)

Wang, Xiaofeng; Perc, Matjaž; Liu, Yongkui; Chen, Xiaojie; Wang, Long

2012-10-01

In spatial games players typically alter their strategy by imitating the most successful or one randomly selected neighbor. Since a single neighbor is taken as reference, the information stemming from other neighbors is neglected, which begets the consideration of alternative, possibly more realistic approaches. Here we show that strategy changes inspired not only by the performance of individual neighbors but rather by entire neighborhoods introduce a qualitatively different evolutionary dynamics that is able to support the stable existence of very small cooperative clusters. This leads to phase diagrams that differ significantly from those obtained by means of pairwise strategy updating. In particular, the survivability of cooperators is possible even by high temptations to defect and over a much wider uncertainty range. We support the simulation results by means of pair approximations and analysis of spatial patterns, which jointly highlight the importance of local information for the resolution of social dilemmas.

Tips for Science Teachers Having Students with Disabilities.

ERIC Educational Resources Information Center

Keller, Ed C., Jr.

This document highlights strategies for teaching science students with common learning disabilities. For each learning disability listed, there are sections on courtesy and several teaching methods with mitigative teaching strategies. Highlighted disabilities include Attention Deficit Disorder (ADD), Emotional Disabilities, Epilepsy, Hearing…

Optimal bridge retrofit strategy to enhance disaster resilience of highway transportation systems.

DOT National Transportation Integrated Search

2014-07-01

This study evaluated the resilience of highway bridges under the multihazard scenario of earthquake in the presence of : flood-induced scour. To mitigate losses incurred from bridge damage during extreme events, bridge retrofit strategies are : selec...

An evaluation of a mitigation strategy for deer-vehicle collisions

USGS Publications Warehouse

Bissonette, John A.; Rosa, Silvia

2012-01-01

High mule deer Odocoileus hemionus mortality in southwestern Utah led to the establishment of a mitigation strategy with two major objectives: 1) reduction of wildlife-vehicle collisions and 2) restoration of landscape connectivity to facilitate wildlife movement across the roaded landscape. During our study, we assessed the effectiveness of the mitigation measures in reducing mule deer mortality in the following ways: 1) we compared the number of deer-vehicle collisions in the newly fenced area with a control area without fencing; 2) we analyzed the ‘end-of-the-fence’ problem, defined here as increased mortality of mule deer at the ends of the 2.4-m high exclusion fences; and 3) we evaluated the frequency of animal crossings of the new underpasses using remotely-sensed cameras and compared them with crossing frequency rates for a 20-year-old control underpass. We compared six years of pre-construction mortality (during 1998-2003) with two years of post-construction data on mortality (during 2005-2006) and found a 98.5% decline in deer mortalities in the treatment (i.e. fenced, jump-outs and underpasses) vs a 2.9% decline in the control (i.e. no fences, no jump-outs and no underpasses). We detected no end-of-the-fence problems related to deer mortality. Migratory movements during fall and spring were clearly reflected in the use of underpass. Overall results demonstrated that the mitigation strategy was effective and reduced the number of deer-vehicle accidents, while allowing wildlife movement across the landscape.

Managing Research in a Risk World

NASA Technical Reports Server (NTRS)

Anton, W.; Havenhill, M.

2014-01-01

The Office of Chief Medical Officer (OCHMO) owns all human health and performance risks managed by the Human System Risk Board (HSRB). While the HSRB manages the risks, the Human Research Program (HRP) manages the research portion of the overall risk mitigation strategy for these risks. The HSRB manages risks according to a process that identifies and analyzes risks, plans risk mitigation and tracks and reviews the implementation of these strategies according to its decisions pertaining to the OCHMO risk posture. HRP manages risk research work using an architecture that describes evidence-based risks, gaps in our knowledge about characterizing or mitigating the risk, and the tasks needed to produce deliverables to fill the gaps and reduce the risk. A planning schedule reflecting expected research milestones is developed, and as deliverables and new evidence are generated, research progress is tracked via the Path to Risk Reduction (PRR) that reflects a risk's research plan for a design reference mission. HRP's risk research process closely interfaces with the HSRB risk management process. As research progresses, new deliverables and evidence are used by the HSRB in conjunction with other operational and non-research evidence to inform decisions pertaining to the likelihood and consequence of the risk and risk posture. Those decisions in turn guide forward work for research as it contributes to overall risk mitigation strategies. As HRP tracks its research work, it aligns its priorities by assessing the effectiveness of its contributions and maintaining specific core competencies that would be invaluable for future work for exploration missions.

A Survey of Registered Dietitians’ Concern and Actions Regarding Climate Change in the United States

PubMed Central

Hawkins, Irana W.; Balsam, Alan L.; Goldman, Robert

2015-01-01

Dietary choices are a tool to reduce greenhouse gas emissions. While registered dietitians are on the front lines of food and nutrition recommendations, it is unclear how many are concerned with climate change and take action in practice in the United States. We explored concern about climate change among registered dietitians, and identified factors that may influence practice-related behaviors. Our study population included a random sample of all registered dietitians credentialed in the United States. Primary data were gathered using a cross-sectional survey. Of the 570 survey responses, 75% strongly agreed or agreed that climate change is an important issue while 34% strongly agreed or agreed that dietitians should play a major role in climate change mitigation strategies. Thirty-eight percent engaged in activities that promoted diet as a climate change mitigation strategy. Vegetarian (p = 0.002) and vegan dietitians (p = 0.007) were significantly more likely than non-vegetarian and non-vegan dietitians to engage in activities that promoted diet as a climate change mitigation strategy. Overall, concern for climate change among dietitians varied significantly by the region of the country in which the dietitian resided, and awareness that animal products are implicated in climate change. Registered dietitians in the United States are concerned with climate change. However, there is a discrepancy between concern and practice-based actions. These results suggest the need for educational and experiential opportunities connecting climate change mitigation to dietetics practice. PMID:26217666

Assessment of Emerging Regional Air Quality (AQ) and Greenhouse Gas (GHG) Impacts and Potential Mitigation Strategies in U.S. Energy Sectors

NASA Astrophysics Data System (ADS)

Kinnon, Michael Mac

The current domestic reliance on high-emitting fossil fuels for energy needs is the key driver of U.S. greenhouse gas (GHG) and pollutant emissions driving both climate change and regional air quality (AQ) concerns. Moving forward, emission sources in U.S. energy sectors will be subjected to changes driven by numerous phenomena, including technology evolution, environmental impacts, sustainability goals, and socioeconomic factors. This evolution will directly affect emissions source-related impacts on regional AQ that effective emissions control strategies must account for, including relative source contributions. Though previous studies have evaluated the emissions and AQ impacts of different sectors, technologies and fuels, most previous studies have assessed emissions impacts only without using advanced atmospheric models to accurately account for both spatial and temporal emissions perturbations and atmospheric chemistry and transport. In addition, few previous studies have considered the integration of multiple technologies and fuels in different U.S. regions.. Finally, most studies do not project emissions several decades into the future to assess what sources should be targeted with priority over time. These aspects are critical for understanding how both emissions sources and potential mitigation strategies impact the formation and fate of primary and secondary pollutants, including ground-level ozone and particulate matter concentrations. Therefore, this work utilizes a set of modeling tools to project and then to spatially and temporally resolve emissions as input into a 3-D Eulerian AQ model to assess how sources of emissions contribute to future atmospheric pollutant burdens. Further, analyses of the potential impacts of alternative energy strategies contained in potential mitigation strategies are conducted for priority targets to develop an understanding of how to maximize AQ benefits and avoid unforeseen deleterious tradeoffs between GHG reduction and AQ. Findings include changes in the relative contribution to AQ that elevate the importance of addressing emissions from all sectors and sources including some that may be more difficult to control, including industry, petroleum refineries, and nonlight duty vehicle transportation sources. Additionally, mitigation strategies must consider the full range of life cycle and system effects in order to avoid AQ tradeoffs spatially and temporally.

Cost-effective strategy to mitigate transportation disruptions in supply chain

NASA Astrophysics Data System (ADS)

Albertzeth, G.; Pujawan, I. N.

2018-04-01

Supply chain disruptions have gained significant attention by scholars. But, even though transportation plays a central role in supply chain, only few studies address transportation disruptions. This research demonstrates a real case of an order delivery process from a focal company (FC) to a single distributor, where transportation disruptions stochastically occurs. Considering the possibility of sales loss during the disruption duration, we proposed a redundant stock, flexible route, and combined flexibility-redundancy (ReFlex) as mitigation strategies and a base case as a risk acceptance strategy. The objective is to find out the best strategy that promotes cost-effectiveness against transportation disruptions. To fulfill this objective, we use simulation modeling and cost-effectiveness analysis (CEA) as our research method. We simulate the delivery process of 5 brands using each strategy to produce two different responses: loss of sales percentage and the incurred costs. Next, using these responses, we evaluate and compare the cost-effectiveness ratio of each strategy using CEA. We found that redundant stock gave the best effectiveness on all brands, ReFlex as the second best, while flexible route gave the least effectiveness. Finally, we recommend which strategy should be applied based on the decision maker willingness to pay.

Roadmap to risk evaluation and mitigation strategies (REMS) success

PubMed Central

Balian, John D.; Malhotra, Rachpal; Perentesis, Valerie

2010-01-01

Medical safety-related risk management is a rapidly evolving and increasingly important aspect of drug approval and market longevity. To effectively meet the challenges of this new era, we describe a risk management roadmap that proactively yet practically anticipates risk-management requirements, provides the foundation for enduring yet appropriately flexible risk-management practices, and leverages these techniques to efficiently and effectively utilize risk evaluation and mitigation strategies (REMS)/risk minimization programs as market access enablers. This fully integrated risk-management paradigm creates exciting opportunities for newer tools, techniques, and approaches to more successfully optimize product development, approval, and commercialization, with patients as the ultimate beneficiaries. PMID:25083193

Efficient mitigation strategies for epidemics in rural regions.

PubMed

Scoglio, Caterina; Schumm, Walter; Schumm, Phillip; Easton, Todd; Roy Chowdhury, Sohini; Sydney, Ali; Youssef, Mina

2010-07-13

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and results of general studies cannot be directly applied since population densities and human mobility factors are very different in rural regions from those in cities. We create a network model of a rural community in Kansas, USA, by collecting data on the contact patterns and computing rates of contact among a sampled population. We model the impact of different mitigation strategies detecting closely connected groups of people and frequently visited locations. Within those groups and locations, we compare the effectiveness of random and targeted vaccinations using a Susceptible-Exposed-Infected-Recovered compartmental model on the contact network. Our simulations show that the targeted vaccinations of only 10% of the sampled population reduced the size of the epidemic by 34.5%. Additionally, if 10% of the population visiting one of the most popular locations is randomly vaccinated, the epidemic size is reduced by 19%. Our results suggest a new implementation of a highly effective strategy for targeted vaccinations through the use of popular locations in rural communities.

Induced seismicity and carbon storage: Risk assessment and mitigation strategies

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Joshua A.; Foxall, William; Bachmann, Corinne

Geologic carbon storage (GCS) is widely recognized as an important strategy to reduce atmospheric carbon dioxide (CO 2) emissions. Like all technologies, however, sequestration projects create a number of potential environmental and safety hazards that must be addressed. These include earthquakes—from microseismicity to large, damaging events—that can be triggered by altering pore-pressure conditions in the subsurface. To date, measured seismicity due to CO 2 injection has been limited to a few modest events, but the hazard exists and must be considered. There are important similarities between CO 2 injection and fluid injection from other applications that have induced significant events—e.g.more » geothermal systems, waste-fluid injection, hydrocarbon extraction, and others. There are also important distinctions among these technologies that should be considered in a discussion of seismic hazard. This report focuses on strategies for assessing and mitigating risk during each phase of a CO 2 storage project. Four key risks related to fault reactivation and induced seismicity were considered. Induced slip on faults could potentially lead to: (1) infrastructure damage, (2) a public nuisance, (3) brine-contaminated drinking water, and (4) CO 2-contaminated drinking water. These scenarios lead to different types of damage—to property, to drinking water quality, or to the public welfare. Given these four risks, this report focuses on strategies for assessing (and altering) their likelihoods of occurrence and the damage that may result. This report begins with an overview of the basic physical mechanisms behind induced seismicity. This science basis—and its gaps—is crucial because it forms the foundation for risk assessment and mitigation. Available techniques for characterizing and monitoring seismic behavior are also described. Again, this technical basis—and its limitations—must be factored into the risk assessment and mitigation approach. A phased approach to risk management is then introduced. The basic goal of the phased approach is to constantly adapt site operations to current conditions and available characterization data. The remainder of the report then focuses in detail on different components of the monitoring, risk assessment, and mitigation strategies. Issues in current seismic risk assessment methods that must be modified to address induce seismicity are highlighted. The report then concludes with several specific recommendations for operators and regulatory authorities to consider when selecting, permitting, and operating a storage project.« less

Methodological systematic review identifies major limitations in prioritization processes for updating.

PubMed

Martínez García, Laura; Pardo-Hernandez, Hector; Superchi, Cecilia; Niño de Guzman, Ena; Ballesteros, Monica; Ibargoyen Roteta, Nora; McFarlane, Emma; Posso, Margarita; Roqué I Figuls, Marta; Rotaeche Del Campo, Rafael; Sanabria, Andrea Juliana; Selva, Anna; Solà, Ivan; Vernooij, Robin W M; Alonso-Coello, Pablo

2017-06-01

The aim of the study was to identify and describe strategies to prioritize the updating of systematic reviews (SRs), health technology assessments (HTAs), or clinical guidelines (CGs). We conducted an SR of studies describing one or more methods to prioritize SRs, HTAs, or CGs for updating. We searched MEDLINE (PubMed, from 1966 to August 2016) and The Cochrane Methodology Register (The Cochrane Library, Issue 8 2016). We hand searched abstract books, reviewed reference lists, and contacted experts. Two reviewers independently screened the references and extracted data. We included 14 studies. Six studies were classified as descriptive (6 of 14, 42.9%) and eight as implementation studies (8 of 14, 57.1%). Six studies reported an updating strategy (6 of 14, 42.9%), six a prioritization process (6 of 14, 42.9%), and two a prioritization criterion (2 of 14, 14.2%). Eight studies focused on SRs (8 of 14, 57.1%), six studies focused on CGs (6 of 14, 42.9%), and none were about HTAs. We identified 76 prioritization criteria that can be applied when prioritizing documents for updating. The most frequently cited criteria were as follows: available evidence (19 of 76, 25.0%), clinical relevance (10 of 76; 13.2%), and users' interest (10 of 76; 13.2%). There is wide variability and suboptimal reporting of the methods used to develop and implement processes to prioritize updating of SRs, HTAs, and CGs. Copyright © 2017 Elsevier Inc. All rights reserved.

To Switch or Not to Switch: Role of Cognitive Control in Working Memory Training in Older Adults.

PubMed

Basak, Chandramallika; O'Connell, Margaret A

2016-01-01

It is currently not known what are the best working memory training strategies to offset the age-related declines in fluid cognitive abilities. In this randomized clinical double-blind trial, older adults were randomly assigned to one of two types of working memory training - one group was trained on a predictable memory updating task (PT) and another group was trained on a novel, unpredictable memory updating task (UT). Unpredictable memory updating, compared to predictable, requires greater demands on cognitive control (Basak and Verhaeghen, 2011a). Therefore, the current study allowed us to evaluate the role of cognitive control in working memory training. All participants were assessed on a set of near and far transfer tasks at three different testing sessions - before training, immediately after the training, and 1.5 months after completing the training. Additionally, individual learning rates for a comparison working memory task (performed by both groups) and the trained task were computed. Training on unpredictable memory updating, compared to predictable, significantly enhanced performance on a measure of episodic memory, immediately after the training. Moreover, individuals with faster learning rates showed greater gains in this episodic memory task and another new working memory task; this effect was specific to UT. We propose that the unpredictable memory updating training, compared to predictable memory updating training, may a better strategy to improve selective cognitive abilities in older adults, and future studies could further investigate the role of cognitive control in working memory training.

Comparing impacts of climate change and mitigation on global agriculture by 2050

NASA Astrophysics Data System (ADS)

van Meijl, Hans; Havlik, Petr; Lotze-Campen, Hermann; Stehfest, Elke; Witzke, Peter; Pérez Domínguez, Ignacio; Bodirsky, Benjamin Leon; van Dijk, Michiel; Doelman, Jonathan; Fellmann, Thomas; Humpenöder, Florian; Koopman, Jason F. L.; Müller, Christoph; Popp, Alexander; Tabeau, Andrzej; Valin, Hugo; van Zeist, Willem-Jan

2018-06-01

Systematic model inter-comparison helps to narrow discrepancies in the analysis of the future impact of climate change on agricultural production. This paper presents a set of alternative scenarios by five global climate and agro-economic models. Covering integrated assessment (IMAGE), partial equilibrium (CAPRI, GLOBIOM, MAgPIE) and computable general equilibrium (MAGNET) models ensures a good coverage of biophysical and economic agricultural features. These models are harmonized with respect to basic model drivers, to assess the range of potential impacts of climate change on the agricultural sector by 2050. Moreover, they quantify the economic consequences of stringent global emission mitigation efforts, such as non-CO2 emission taxes and land-based mitigation options, to stabilize global warming at 2 °C by the end of the century under different Shared Socioeconomic Pathways. A key contribution of the paper is a vis-à-vis comparison of climate change impacts relative to the impact of mitigation measures. In addition, our scenario design allows assessing the impact of the residual climate change on the mitigation challenge. From a global perspective, the impact of climate change on agricultural production by mid-century is negative but small. A larger negative effect on agricultural production, most pronounced for ruminant meat production, is observed when emission mitigation measures compliant with a 2 °C target are put in place. Our results indicate that a mitigation strategy that embeds residual climate change effects (RCP2.6) has a negative impact on global agricultural production relative to a no-mitigation strategy with stronger climate impacts (RCP6.0). However, this is partially due to the limited impact of the climate change scenarios by 2050. The magnitude of price changes is different amongst models due to methodological differences. Further research to achieve a better harmonization is needed, especially regarding endogenous food and feed demand, including substitution across individual commodities, and endogenous technological change.

Analyzing costs of space debris mitigation methods

NASA Astrophysics Data System (ADS)

Wiedemann, C.; Krag, H.; Bendisch, J.; Sdunnus, H.

The steadily increasing number of space objects poses a considerable hazard to all kinds of spacecraft. To reduce the risks to future space missions different debris mitigation measures and spacecraft protection techniques have been investigated during the last years. However, the economic efficiency has not been considered yet in this context. This economical background is not always clear to satellite operators and the space industry. Current studies have the objective to evaluate the mission costs due to space debris in a business as usual (no mitigation) scenario compared to the missions costs considering debris mitigation. The aim i an estimation of thes time until the investment in debris mitigation will lead to an effective reduction of mission costs. This paper presents the results of investigations on the key problems of cost estimation for spacecraft and the influence of debris mitigation and shielding on cost. The shielding of a satellite can be an effective method to protect the spacecraft against debris impact. Mitigation strategies like the reduction of orbital lifetime and de- or re-orbit of non-operational satellites are methods to control the space debris environment. These methods result in an increase of costs. In a first step the overall costs of different types of unmanned satellites are analyzed. The key problem is, that it is not possible to provide a simple cost model that can be applied to all types of satellites. Unmanned spacecraft differ very much in mission, complexity of design, payload and operational lifetime. It is important to classify relevant cost parameters and investigate their influence on the respective mission. The theory of empirical cost estimation and existing cost models are discussed. A selected cost model is simplified and generalized for an application on all operational satellites. In a next step the influence of space debris on cost is treated, if the implementation of mitigation strategies is considered.

Strategies to Prevent Surgical Site Infections in Acute Care Hospitals: 2014 Update

PubMed Central

Anderson, Deverick J.; Podgorny, Kelly; Berríos-Torres, Sandra I.; Bratzler, Dale W.; Dellinger, E. Patchen; Greene, Linda; Nyquist, Ann-Christine; Saiman, Lisa; Yokoe, Deborah S.; Maragakis, Lisa L.; Kaye, Keith S.

2014-01-01

PURPOSE Previously published guidelines are available that provide comprehensive recommendations for detecting and preventing healthcare-associated infections (HAIs). The intent of this document is to highlight practical recommendations in a concise format designed to assist acute care hospitals in implementing and prioritizing their surgical site infection (SSI) prevention efforts. This document updates “Strategies to Prevent Surgical Site Infections in Acute Care Hospitals,”1 published in 2008. This expert guidance document is sponsored by the Society for Healthcare Epidemiology of America (SHEA) and is the product of a collaborative effort led by SHEA, the Infectious Diseases Society of America (IDSA), the American Hospital Association (AHA), the Association for Professionals in Infection Control and Epidemiology (APIC), and The Joint Commission, with major contributions from representatives of a number of organizations and societies with content expertise. The list of endorsing and supporting organizations is presented in the introduction to the 2014 updates.2 PMID:24799638

Launch flexibility using NLP guidance and remote wind sensing

NASA Technical Reports Server (NTRS)

Cramer, Evin J.; Bradt, Jerre E.; Hardtla, John W.

1990-01-01

This paper examines the use of lidar wind measurements in the implementation of a guidance strategy for a nonlinear programming (NLP) launch guidance algorithm. The NLP algorithm uses B-spline command function representation for flexibility in the design of the guidance steering commands. Using this algorithm, the guidance system solves a two-point boundary value problem at each guidance update. The specification of different boundary value problems at each guidance update provides flexibility that can be used in the design of the guidance strategy. The algorithm can use lidar wind measurements for on pad guidance retargeting and for load limiting guidance steering commands. Examples presented in the paper use simulated wind updates to correct wind induced final orbit errors and to adjust the guidance steering commands to limit the product of the dynamic pressure and angle-of-attack for launch vehicle load alleviation.

Emergence of cooperation in non-scale-free networks

NASA Astrophysics Data System (ADS)

Zhang, Yichao; Aziz-Alaoui, M. A.; Bertelle, Cyrille; Zhou, Shi; Wang, Wenting

2014-06-01

Evolutionary game theory is one of the key paradigms behind many scientific disciplines from science to engineering. Previous studies proposed a strategy updating mechanism, which successfully demonstrated that the scale-free network can provide a framework for the emergence of cooperation. Instead, individuals in random graphs and small-world networks do not favor cooperation under this updating rule. However, a recent empirical result shows the heterogeneous networks do not promote cooperation when humans play a prisoner’s dilemma. In this paper, we propose a strategy updating rule with payoff memory. We observe that the random graphs and small-world networks can provide even better frameworks for cooperation than the scale-free networks in this scenario. Our observations suggest that the degree heterogeneity may be neither a sufficient condition nor a necessary condition for the widespread cooperation in complex networks. Also, the topological structures are not sufficed to determine the level of cooperation in complex networks.

Propagation of Bayesian Belief for Near-Real Time Statistical Assessment of Geosynchronous Satellite Status Based on Non-Resolved Photometry Data

DTIC Science & Technology

2014-09-01

of the BRDF for the Body and Panel. In order to provide a continuously updated baseline, the Photometry Model application is performed using a...brightness to its predicted brightness. The brightness predictions can be obtained using any analytical model chosen by the user. The inference for a...the analytical model as possible; and to mitigate the effect of bias that could be introduced by the choice of analytical model . It considers that a

Towards a new surface and internal charging design guideline for the 21st century

NASA Technical Reports Server (NTRS)

Garrett, Henry B.; Whittlesey, Albert C.

2005-01-01

This paper will describe the status of those on-going efforts to combine and update the two guidelines with emphasis on the proposed contents and on the differences and similarities between surface and internal charging mitigation techniques. It is planned to have a draft revision ready for review by the spacecraft charging community by the fall of 2005, with 2006 dedicated to implementing reviewers' comments and additions leading to a new, officially approved NASA guideline by the fall of 2006.

"As Good as Your Word": Face-Threat Mitigation and the Use of Instructor Nonverbal Cues on Students' Perceptions of Digital Feedback

ERIC Educational Resources Information Center

Clark-Gordon, Cathlin V.; Bowman, Nicholas D.; Watts, Evan R.; Banks, Jaime; Knight, Jennifer M.

2018-01-01

Research has established that students often consider the delivery of instructor feedback to be a face-threatening event. To minimize the potential negative effects of feedback, verbal and nonverbal face-threat mitigation (FTM) strategies are utilized by instructors. Advances in digital feedback systems, like online documents and learning…

Is climate change modifying precipitation extremes?

NASA Astrophysics Data System (ADS)

Montanari, Alberto; Papalexiou, Simon Michael

2016-04-01

The title of the present contribution is a relevant question that is frequently posed to scientists, technicians and managers of local authorities. Although several research efforts were recently dedicated to rainfall observation, analysis and modelling, the above question remains essentially unanswered. The question comes from the awareness that the frequency of floods and the related socio-economic impacts are increasing in many countries, and climate change is deemed to be the main trigger. Indeed, identifying the real reasons for the observed increase of flood risk is necessary in order to plan effective mitigation and adaptation strategies. While mitigation of climate change is an extremely important issue at the global level, at small spatial scales several other triggers may interact with it, therefore requiring different mitigation strategies. Similarly, the responsibilities of administrators are radically different at local and global scales. This talk aims to provide insights and information to address the question expressed by its title. High resolution and long term rainfall data will be presented, as well as an analysis of the frequency of their extremes and its progress in time. The results will provide pragmatic indications for the sake of better planning flood risk mitigation policies.

Potential Upstream Strategies for the Mitigation of Pharmaceuticals in the Aquatic Environment: a Brief Review.

PubMed

Blair, Benjamin D

2016-06-01

Active pharmaceutical ingredients represent a class of pollutants of emerging concern, and there is growing evidence that these pollutants can cause damage to the aquatic environment. As regulations to address these concerns are expected in developed nations, decision-makers are looking to the scientific community for potential solutions. To inform these regulatory efforts, further information on the potential strategies to reduce the levels of pharmaceuticals entering the aquatic environment is needed. End-of-pipe (i.e., wastewater treatment) technologies that can remove pharmaceuticals exist; however, they are costly to install and operate. Thus, the goal of this brief review is to look beyond end-of-pipe solutions and present various upstream mitigation strategies discussed within the scientific literature. Programs such as pharmaceutical take-back programs currently exist to attempt to reduce pharmaceutical concentrations in the environment, although access and coverage are often limited for many programs. Other potential strategies include redesigning pharmaceuticals to minimize aquatic toxicity, increasing the percent of the pharmaceuticals metabolized in the body, selecting less harmful pharmaceuticals for use, starting new prescriptions at lower dosages, selecting pharmaceuticals with lower excretion rates, and implementing source treatment such as urine separating toilets. Overall, this brief review presents a summary of the upstream preventative recommendations to mitigate pharmaceuticals from entering the aquatic environment with an emphasis on regulatory efforts in the USA and concludes with priorities for further research.

Lunar Dust Mitigation Technology Development

NASA Technical Reports Server (NTRS)

Hyatt, Mark J.; Deluane, Paul B.

2008-01-01

NASA s plans for implementing the Vision for Space Exploration include returning to the moon as a stepping stone for further exploration of Mars, and beyond. Dust on the lunar surface has a ubiquitous presence which must be explicitly addressed during upcoming human lunar exploration missions. While the operational challenges attributable to dust during the Apollo missions did not prove critical, the comparatively long duration of impending missions presents a different challenge. Near term plans to revisit the moon places a primary emphasis on characterization and mitigation of lunar dust. Comprised of regolith particles ranging in size from tens of nanometers to microns, lunar dust is a manifestation of the complex interaction of the lunar soil with multiple mechanical, electrical, and gravitational effects. The environmental and anthropogenic factors effecting the perturbation, transport, and deposition of lunar dust must be studied in order to mitigate it s potentially harmful effects on exploration systems. This paper presents the current perspective and implementation of dust knowledge management and integration, and mitigation technology development activities within NASA s Exploration Technology Development Program. This work is presented within the context of the Constellation Program s Integrated Lunar Dust Management Strategy. The Lunar Dust Mitigation Technology Development project has been implemented within the ETDP. Project scope and plans will be presented, along with a a perspective on lessons learned from Apollo and forensics engineering studies of Apollo hardware. This paper further outlines the scientific basis for lunar dust behavior, it s characteristics and potential effects, and surveys several potential strategies for its control and mitigation both for lunar surface operations and within the working volumes of a lunar outpost.

Information Technology Management Strategies to Implement Knowledge Management Systems

ERIC Educational Resources Information Center

McGee, Mary Jane Christy

2017-01-01

More than 38% of the U.S. public workforce will likely retire by 2030, which may result in a labor shortage. Business leaders may adopt strategies to mitigate knowledge loss within their organizations by capturing knowledge in a knowledge management system (KMS). The purpose of this single case study was to explore strategies that information…

An Update on Strategic Learning: It's More Than Textbook Reading Strategies.

ERIC Educational Resources Information Center

Simpson, Michele L.; Nist, Sherrie L.

2000-01-01

Reviews research investigating strategies for reading and studying at the college level. Examines 5 generalizations that emerged: (1) task understanding is critical to strategic learning; (2) beliefs about learning influence how students read and study; (3) quality instruction is essential; (4) a variety of research-based strategies should be…

Transit research and industry news update : August 2009.

DOT National Transportation Integrated Search

2009-08-01

SPECIAL............................................................................................................................3 : Moving Cooler: An Analysis of Transportation Strategies for Reducing Greenhouse Gas Emissions.........................

Summary of breakout session f: facility and equipment decontamination strategies.

PubMed

Norwood, Laurie P; Suvarna, Kalavati

2011-01-01

CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December 1-3, 2010 Guest Editors: Arifa Khan (Bethesda, MD), Patricia Hughes (Bethesda, MD) and Michael Wiebe (San Francisco, CA).

The influence of parametric and external noise in act-and-wait control with delayed feedback.

PubMed

Wang, Jiaxing; Kuske, Rachel

2017-11-01

We apply several novel semi-analytic approaches for characterizing and calculating the effects of noise in a system with act-and-wait control. For concrete illustration, we apply these to a canonical balance model for an inverted pendulum to study the combined effect of delay and noise within the act-and-wait setting. While the act-and-wait control facilitates strong stabilization through deadbeat control, a comparison of different models with continuous vs. discrete updating of the control strategy in the active period illustrates how delays combined with the imprecise application of the control can seriously degrade the performance. We give several novel analyses of a generalized act-and-wait control strategy, allowing flexibility in the updating of the control strategy, in order to understand the sensitivities to delays and random fluctuations. In both the deterministic and stochastic settings, we give analytical and semi-analytical results that characterize and quantify the dynamics of the system. These results include the size and shape of stability regions, densities for the critical eigenvalues that capture the rate of reaching the desired stable equilibrium, and amplification factors for sustained fluctuations in the context of external noise. They also provide the dependence of these quantities on the length of the delay and the active period. In particular, we see that the combined influence of delay, parametric error, or external noise and on-off control can qualitatively change the dynamics, thus reducing the robustness of the control strategy. We also capture the dependence on how frequently the control is updated, allowing an interpolation between continuous and frequent updating. In addition to providing insights for these specific models, the methods we propose are generalizable to other settings with noise, delay, and on-off control, where analytical techniques are otherwise severely scarce.

Defense.gov - Special Report: Travels with Mullen

Science.gov Websites

updated and may no longer be applicable as a result of changes in law, regulation and/or administration 2009 Top Stories Mullen Updates, Changes Joint Guidance WASHINGTON, Dec. 21, 2009 – The Afghanistan trip to Afghanistan, Pakistan and Iraq has given him an opportunity to assess changes in strategy and

Designing Adult Learning Strategies: The Case of South Eastern Europe

ERIC Educational Resources Information Center

Gunny, Madeleine; Viertel, Evelyn

2006-01-01

The importance of lifelong learning is generally well understood and few people today would query the need for adults to regularly update their skills in line with labour market needs, and for governments and social partners to provide an environment that supports skills acquisition and updating. However, it is clear when we look at data from the…

[Carbon capture and storage (CCS) and its potential role to mitigate carbon emission in China].

PubMed

Chen, Wen-Ying; Wu, Zong-Xin; Wang, Wei-Zhong

2007-06-01

Carbon capture and storage (CCS) has been widely recognized as one of the options to mitigate carbon emission to eventually stabilize carbon dioxide concentration in the atmosphere. Three parts of CCS, which are carbon capture, transport, and storage are assessed in this paper, covering comparisons of techno-economic parameters for different carbon capture technologies, comparisons of storage mechanism, capacity and cost for various storage formations, and etc. In addition, the role of CCS to mitigate global carbon emission is introduced. Finally, China MARKAL model is updated to include various CCS technologies, especially indirect coal liquefaction and poly-generation technologies with CCS, in order to consider carbon emission reduction as well as energy security issue. The model is used to generate different scenarios to study potential role of CCS to mitigate carbon emissions by 2050 in China. It is concluded that application of CCS can decrease marginal abatement cost and the decrease rate can reach 45% for the emission reduction rate of 50%, and it can lessen the dependence on nuclear power development for stringent carbon constrains. Moreover, coal resources can be cleanly used for longer time with CCS, e.g., for the scenario C70, coal share in the primary energy consumption by 2050 will increase from 10% when without CCS to 30% when with CCS. Therefore, China should pay attention to CCS R&D activities and to developing demonstration projects.

phMRI: methodological considerations for mitigating potential confounding factors

PubMed Central

Bourke, Julius H.; Wall, Matthew B.

2015-01-01

Pharmacological Magnetic Resonance Imaging (phMRI) is a variant of conventional MRI that adds pharmacological manipulations in order to study the effects of drugs, or uses pharmacological probes to investigate basic or applied (e.g., clinical) neuroscience questions. Issues that may confound the interpretation of results from various types of phMRI studies are briefly discussed, and a set of methodological strategies that can mitigate these problems are described. These include strategies that can be employed at every stage of investigation, from study design to interpretation of resulting data, and additional techniques suited for use with clinical populations are also featured. Pharmacological MRI is a challenging area of research that has both significant advantages and formidable difficulties, however with due consideration and use of these strategies many of the key obstacles can be overcome. PMID:25999812

Patent cliff mitigation strategies: giving new life to blockbusters.

PubMed

Kakkar, Ashish Kumar

2015-01-01

With several blockbuster drugs on the brink of another significant patent expiry cliff, innovator pharmaceutical firms are at risk of losing billions of dollars in sales to generic competition. With issues such as staggering R&D costs, reduced productivity and increasing governmental emphasis on pharmacoeconomics, timely planning and implementation of product lifecycle management strategies is becoming indispensable. A variety of strategies designed to mitigate the post-patent expiry revenue loss exist. These approaches range from fairly straightforward measures, such as strategic price cuts and launching own or authorized generics, to complex and lengthy ones, such as new formulations and indications that require companies to reinvent their pharmaceuticals. As patent expiries loom and product pipelines continue to remain thin, proactive planning for generic entry will be critical for pharma companies to drive growth and earnings in a sustainable manner.

HST/WFC3 Characteristics: gain, post-flash stability, UVIS low-sensitivity pixels, persistence, IR flats and bad pixel table

NASA Astrophysics Data System (ADS)

Gunning, Heather C.; Baggett, Sylvia; Gosmeyer, Catherine M.; Long, Knox S.; Ryan, Russell E.; MacKenty, John W.; Durbin, Meredith

2015-08-01

The Wide Field Camera 3 (WFC3) is a fourth-generation imaging instrument on the Hubble Space Telescope (HST). Installed in May 2009, WFC3 is comprised of two observational channels covering wavelengths from UV/Visible (UVIS) to infrared (IR); both have been performing well on-orbit. We discuss the gain stability of both WFC3 channel detectors from ground testing through present day. For UVIS, we detail a low-sensitivity pixel population that evolves during the time between anneals, but is largely reset by the annealing procedure. We characterize the post-flash LED lamp stability, used and recommended to mitigate CTE effects for observations with less than 12e-/pixel backgrounds. We present mitigation options for IR persistence during and after observations. Finally, we give an overview on the construction of the IR flats and provide updates on the bad pixel table.

Investigation of adaptive filtering and MDL mitigation based on space-time block-coding for spatial division multiplexed coherent receivers

NASA Astrophysics Data System (ADS)

Weng, Yi; He, Xuan; Yao, Wang; Pacheco, Michelle C.; Wang, Junyi; Pan, Zhongqi

2017-07-01

In this paper, we explored the performance of space-time block-coding (STBC) assisted multiple-input multiple-output (MIMO) scheme for modal dispersion and mode-dependent loss (MDL) mitigation in spatial-division multiplexed optical communication systems, whereas the weight matrices of frequency-domain equalization (FDE) were updated heuristically using decision-directed recursive least squares (RLS) algorithm for convergence and channel estimation. The proposed STBC-RLS algorithm can achieve 43.6% enhancement on convergence rate over conventional least mean squares (LMS) for quadrature phase-shift keying (QPSK) signals with merely 16.2% increase in hardware complexity. The overall optical signal to noise ratio (OSNR) tolerance can be improved via STBC by approximately 3.1, 4.9, 7.8 dB for QPSK, 16-quadrature amplitude modulation (QAM) and 64-QAM with respective bit-error-rates (BER) and minimum-mean-square-error (MMSE).

Advanced Insider Threat Mitigation Workshop Instructional Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gibbs, Philip; Larsen, Robert; O'Brien, Mike

Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt and protracted theft of nuclear materials. This particular set of materials is an update of a January 2008 version to add increased emphasis on Material Control and Accounting and its role with respect to protracted insider nuclear material theft scenarios. This report is a compilation of workshop materials consisting of lectures on technical and administrative measures used in Physical Protection (PP) and Material Control and Accounting (MC&A) and methods for analyzing theirmore » effectiveness against a postulated insider threat. The postulated threat includes both abrupt and protracted theft scenarios. Presentation is envisioned to be through classroom instruction and discussion. Several practical and group exercises are included for demonstration and application of the analysis approach contained in the lecture/discussion sessions as applied to a hypothetical nuclear facility.« less

Mitigation of Late Renal and Pulmonary Injury After Hematopoietic Stem Cell Transplantation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohen, Eric P., E-mail: Eric.Cohen2@va.gov; Bedi, Manpreet; Irving, Amy A.

Purpose: To update the results of a clinical trial that assessed whether the angiotensin-converting enzyme inhibitor captopril was effective in mitigating chronic renal failure and pulmonary-related mortality in subjects undergoing total body irradiation (TBI) in preparation for hematopoietic stem cell transplantation (HSCT). Methods and Materials: Updated records of the 55 subjects who were enrolled in this randomized controlled trial were analyzed. Twenty-eight patients received captopril, and 27 patients received placebo. Definitions of TBI-HSCT-related chronic renal failure (and relapse) were the same as those in the 2007 analysis. Pulmonary-related mortality was based on clinical or autopsy findings of pulmonary failure ormore » infection as the primary cause of death. Follow-up data for overall and pulmonary-related mortality were supplemented by use of the National Death Index. Results: The risk of TBI-HSCT-related chronic renal failure was lower in the captopril group (11% at 4 years) than in the placebo group (17% at 4 years), but this was not statistically significant (p > 0.2). Analysis of mortality was greatly extended by use of the National Death Index, and no patients were lost to follow-up for reasons other than death prior to 67 months. Patient survival was higher in the captopril group than in the placebo group, but this was not statistically significant (p > 0.2). The improvement in survival was influenced more by a decrease in pulmonary mortality (11% risk at 4 years in the captopril group vs. 26% in the placebo group, p = 0.15) than by a decrease in chronic renal failure. There was no adverse effect on relapse risk (p = 0.4). Conclusions: Captopril therapy produces no detectable adverse effects when given after TBI. Captopril therapy reduces overall and pulmonary-related mortality after radiation-based HSCT, and there is a trend toward mitigation of chronic renal failure.« less

Long-term prospects: Mitigation of supernova and gamma-ray burst threat to intelligent beings

NASA Astrophysics Data System (ADS)

Ćirković, Milan M.; Vukotić, Branislav

2016-12-01

We consider global catastrophic risks due to cosmic explosions (supernovae, magnetars and gamma-ray bursts) and possible mitigation strategies by humans and other hypothetical intelligent beings. While by their very nature these events are so huge to daunt conventional thinking on mitigation and response, we wish to argue that advanced technological civilizations would be able to develop efficient responses in the domain of astroengineering within their home planetary systems. In particular, we suggest that construction of shielding swarms of small objects/particles confined by electromagnetic fields could be one way of mitigating the risk of cosmic explosions and corresponding ionizing radiation surges. Such feats of astroengineering could, in principle, be detectable from afar by advanced Dysonian SETI searches.

Development and Psychometric Analysis of a Nurses’ Attitudes and Skills Safety Scale: Initial Results

PubMed Central

Armstrong, Gail E.; Dietrich, Mary; Norman, Linda; Barnsteiner, Jane; Mion, Lorraine

2016-01-01

Health care organizations have incorporated updated safety principles in the analysis of errors and in norms and standards. Yet no research exists that assesses bedside nurses’ perceived skills or attitudes toward updated safety concepts. The aims of this study were to develop a scale assessing nurses’ perceived skills and attitudes toward updated safety concepts, determine content validity, and examine internal consistency of the scale and subscales. Understanding nurses’ perceived skills and attitudes about safety concepts can be used in targeting strategies to enhance their safety practices. PMID:27479518

Development and Psychometric Analysis of a Nurses' Attitudes and Skills Safety Scale: Initial Results.

PubMed

Armstrong, Gail E; Dietrich, Mary; Norman, Linda; Barnsteiner, Jane; Mion, Lorraine

Health care organizations have incorporated updated safety principles in the analysis of errors and in norms and standards. Yet no research exists that assesses bedside nurses' perceived skills or attitudes toward updated safety concepts. The aims of this study were to develop a scale assessing nurses' perceived skills and attitudes toward updated safety concepts, determine content validity, and examine internal consistency of the scale and subscales. Understanding nurses' perceived skills and attitudes about safety concepts can be used in targeting strategies to enhance their safety practices.

Assessment of human thermal comfort and mitigation measures in different urban climatotopes

NASA Astrophysics Data System (ADS)

Müller, N.; Kuttler, W.

2012-04-01

This study analyses thermal comfort in the model city of Oberhausen as an example for the densely populated metropolitan region Ruhr, Germany. As thermal loads increase due to climate change negative impacts especially for city dwellers will arise. Therefore mitigation strategies should be developed and considered in urban planning today to prevent future thermal stress. The method consists of the combination of in-situ measurements and numerical model simulations. So in a first step the actual thermal situation is determined and then possible mitigation strategies are derived. A measuring network was installed in eight climatotopes for a one year period recording air temperature, relative humidity, wind speed and wind direction. Based on these parameters the human thermal comfort in terms of physiological equivalent temperature (PET) was calculated by RayMan Pro software. Thus the human comfort of different climatotopes was determined. Heat stress in different land uses varies, so excess thermal loads in urban areas could be detected. Based on the measuring results mitigation strategies were developed, such as increasing areas with high evaporation capacity (green areas and water bodies). These strategies were implemented as different plan scenarios in the microscale urban climate model ENVI-met. The best measure should be identified by comparing the range and effect of these scenarios. Simulations were run in three of the eight climatotopes (city center, suburban and open land site) to analyse the effectiveness of the mitigation strategies in several land use structures. These cover the range of values of all eight climatotopes and therefore provide representative results. In the model area of 21 ha total, the modified section in the different plan scenarios was 1 ha. Thus the effect of small-scale changes could be analysed. Such areas can arise due to population decline and structural changes and hold conversion potential. Emphasis was also laid on analysing the effectiveness of water bodies, which need further research in contrast to well analysed vegetation areas. Results show different thermal loads in the miscellaneous climatotopes due to land use structures. Both measurements and model simulations demonstrate the positive effect on thermal comfort due to augmentation of areas with high evaporation capacity. These effects can be especially well detected in summer, when heat stress is most pronounced. The measurement based PET calculations show a maximum difference of 4 K PET between inner city and open land site in summer nights. Simulation results overall present a PET reduction of 1-3 K. The average PET reduction in the city center site is about 2 K, while the maximum reduction in the suburban site can exceed 5 K. In urban areas parks are particularly advisable as mitigation measure, because they reduce thermal stress both by tree shading and evapotranspiration.

Land-Use Portfolio Modeler, Version 1.0

USGS Publications Warehouse

Taketa, Richard; Hong, Makiko

2010-01-01

Natural hazards pose significant threats to the public safety and economic health of many communities throughout the world. Community leaders and decision-makers continually face the challenges of planning and allocating limited resources to invest in protecting their communities against catastrophic losses from natural-hazard events. Public efforts to assess community vulnerability and encourage loss-reduction measures through mitigation often focused on either aggregating site-specific estimates or adopting standards based upon broad assumptions about regional risks. The site-specific method usually provided the most accurate estimates, but was prohibitively expensive, whereas regional risk assessments were often too general to be of practical use. Policy makers lacked a systematic and quantitative method for conducting a regional-scale risk assessment of natural hazards. In response, Bernknopf and others developed the portfolio model, an intermediate-scale approach to assessing natural-hazard risks and mitigation policy alternatives. The basis for the portfolio-model approach was inspired by financial portfolio theory, which prescribes a method of optimizing return on investment while reducing risk by diversifying investments in different security types. In this context, a security type represents a unique combination of features and hazard-risk level, while financial return is defined as the reduction in losses resulting from an investment in mitigation of chosen securities. Features are selected for mitigation and are modeled like investment portfolios. Earth-science and economic data for the features are combined and processed in order to analyze each of the portfolios, which are then used to evaluate the benefits of mitigating the risk in selected locations. Ultimately, the decision maker seeks to choose a portfolio representing a mitigation policy that maximizes the expected return-on-investment, while minimizing the uncertainty associated with that return-on-investment. The portfolio model, now known as the Land-Use Portfolio Model (LUPM), provided the framework for the development of the Land-Use Portfolio Modeler, Version 1.0 software (LUPM v1.0). The software provides a geographic information system (GIS)-based modeling tool for evaluating alternative risk-reduction mitigation strategies for specific natural-hazard events. The modeler uses information about a specific natural-hazard event and the features exposed to that event within the targeted study region to derive a measure of a given mitigation strategy`s effectiveness. Harnessing the spatial capabilities of a GIS enables the tool to provide a rich, interactive mapping environment in which users can create, analyze, visualize, and compare different

Classroom Instruction That Works, Second Edition: Research Report

ERIC Educational Resources Information Center

Beesley, Andrea D., Ed.; Apthorp, Helen S., Ed.

2010-01-01

Background: The current study updates and extends the original research synthesis of effective instructional strategies presented in "Classroom Instruction that Works" ("CITW"; Marzano, Pickering, & Pollock, 2001). That work identified nine instructional strategies for improving academic achievement and synthesized findings from previous…

NASA Electronic Parts and Packaging Field Programmable Gate Array Single Event Effects Test Guideline Update

NASA Technical Reports Server (NTRS)

Berg, Melanie D.; LaBel, Kenneth A.

2018-01-01

The following are updated or new subjects added to the FPGA SEE Test Guidelines manual: academic versus mission specific device evaluation, single event latch-up (SEL) test and analysis, SEE response visibility enhancement during radiation testing, mitigation evaluation (embedded and user-implemented), unreliable design and its affects to SEE Data, testing flushable architectures versus non-flushable architectures, intellectual property core (IP Core) test and evaluation (addresses embedded and user-inserted), heavy-ion energy and linear energy transfer (LET) selection, proton versus heavy-ion testing, fault injection, mean fluence to failure analysis, and mission specific system-level single event upset (SEU) response prediction. Most sections within the guidelines manual provide information regarding best practices for test structure and test system development. The scope of this manual addresses academic versus mission specific device evaluation and visibility enhancement in IP Core testing.

NASA Electronic Parts and Packaging (NEPP) Field Programmable Gate Array (FPGA) Single Event Effects (SEE) Test Guideline Update

NASA Technical Reports Server (NTRS)

Berg, Melanie D.; LaBel, Kenneth A.

2018-01-01

The following are updated or new subjects added to the FPGA SEE Test Guidelines manual: academic versus mission specific device evaluation, single event latch-up (SEL) test and analysis, SEE response visibility enhancement during radiation testing, mitigation evaluation (embedded and user-implemented), unreliable design and its affects to SEE Data, testing flushable architectures versus non-flushable architectures, intellectual property core (IP Core) test and evaluation (addresses embedded and user-inserted), heavy-ion energy and linear energy transfer (LET) selection, proton versus heavy-ion testing, fault injection, mean fluence to failure analysis, and mission specific system-level single event upset (SEU) response prediction. Most sections within the guidelines manual provide information regarding best practices for test structure and test system development. The scope of this manual addresses academic versus mission specific device evaluation and visibility enhancement in IP Core testing.

Federal Transit Administration's noise and vibration Guidance Manual: Updates after 10 years of experience

NASA Astrophysics Data System (ADS)

Hanson, Carl E.

2005-09-01

In April 1995, the Federal Transit Administration of the U.S. Department of Transportation issued its guidance manual, ``Transit Noise and Vibration Impact Assessment.'' The manual was written to provide direction for the preparation of noise and vibration sections of environmental documents for public transportation projects in the interest of promoting quality and uniformity in assessments. In the 10 years since its release, the guidance manual has been used as the basis of noise and vibration assessments in over 80 environmental documents and has been used worldwide as a standard method for performing transit noise analyses. An updated version has recently been prepared that takes account of improvements in tools, changes in the environmental assessment procedures, modifications of impact criteria, and experience with mitigation measures. These factors, and other background information, will be discussed to provide insight regarding the revisions in the new edition.

Salmonella Growth and Deposition Inside Eggs: Implications for Refrigeration as a Control Strategy

USDA-ARS?s Scientific Manuscript database

A recent risk assessment for Salmonella Enteritidis contamination of eggs concluded that prompt refrigeration of freshly laid eggs was among the most promising disease mitigation strategies. ARS research has provided detailed information about the deposition, movement, and multiplication of Salmonel...

Sex-Related Strategies for Coping With Interpersonal Conflict in Children Aged Five and Seven.

ERIC Educational Resources Information Center

Miller, Patrice M.; And Others

1986-01-01

Explores the differences between boys and girls (5- and 7-year-olds) in their use of two kinds of strategies with interpersonal conflict: (1) active persuasion and negotiation, and (2) mitigation without disrupting social harmony between the interactors. (HOD)

Whole-farm models to quantify greenhouse gas emissions and their potential use for linking climate change mitigation and adaptation in temperate grassland ruminant-based farming systems.

PubMed

Del Prado, A; Crosson, P; Olesen, J E; Rotz, C A

2013-06-01

The farm level is the most appropriate scale for evaluating options for mitigating greenhouse gas (GHG) emissions, because the farm represents the unit at which management decisions in livestock production are made. To date, a number of whole farm modelling approaches have been developed to quantify GHG emissions and explore climate change mitigation strategies for livestock systems. This paper analyses the limitations and strengths of the different existing approaches for modelling GHG mitigation by considering basic model structures, approaches for simulating GHG emissions from various farm components and the sensitivity of GHG outputs and mitigation measures to different approaches. Potential challenges for linking existing models with the simulation of impacts and adaptation measures under climate change are explored along with a brief discussion of the effects on other ecosystem services.

Using No-Stakes Educational Testing to Mitigate Summer Learning Loss: A Pilot Study. Research Report. ETS RR-14-21

ERIC Educational Resources Information Center

Zaromb, Franklin; Adler, Rachel M.; Bruce, Kelly; Attali, Yigal; Rock, JoAnn

2014-01-01

This study investigates the benefits of no-stakes educational testing during students' summer vacation as a strategy to mitigate summer learning loss. Fifty-one students in Grades 3-8 from the Every Child Valued (ECV) and Lawrence Community Center (LCC) summer programs in Lawrenceville, NJ, took short, online assessments throughout the summer,…

Goals, obstacles and effective strategies of wildfire mitigation programs in the Wildland-Urban Interface

Treesearch

Margaret A. Reams; Terry K. Haines; Cheryl R. Renner; Michael W. Wascom; Harish Kingre

2005-01-01

The dramatic expansion into the Wildland–Urban Interface (WUI) places property, natural assets, and human life at risk from wildfire destruction. The U.S. National Fire Plan encourages communities to implement laws and outreach programs for pre-fire planning to mitigate the risk to area residents. Starting in 2003, we surveyed the administrators of regulatory and...

Impacts of Storm Surge Mitigation Strategies on Aboveground Storage Tank Chemical Spill Transport

NASA Astrophysics Data System (ADS)

Do, C.; Bass, B. J.; Bernier, C.; Samii, A.; Dawson, C.; Bedient, P. B.

2017-12-01

The Houston Ship Channel (HSC), located in the hurricane-prone Houston-Galveston region of the upper Texas Coast, is one of the busiest waterways in the United States and is home to one of the largest petrochemical complexes in the world. Due to the proximity of the HSC to Galveston Bay and the Gulf of Mexico, chemical spills resulting from storm surge damage to aboveground storage tanks (ASTs) pose serious threats to the environment, residential communities, and national/international markets whose activities in the HSC generate billions of dollars annually. In an effort to develop a comprehensive storm surge mitigation strategy for Galveston Bay and its constituents, Rice University's Severe Storm Prediction, Education, and Evacuation from Disasters Center proposed two structural storm surge mitigation concepts, the Mid Bay Structure (MBS) and the Lower Bay Structure (LBS) as components of the Houston-Galveston Area Protection System (H-GAPS) project. The MBS consists of levees along the HSC and a navigational gate across the channel, and the LBS consists of a navigation gate and environmental gates across Bolivar Road. The impacts of these two barrier systems on the fate of AST chemical spills in the HSC have previously been unknown. This study applies the coupled 2D SWAN+ADCIRC model to simulate hurricane storm surge circulation within the Gulf of Mexico and Galveston Bay due to a synthetic storm which results in approximately 250-year surge levels in Galveston Bay. The SWAN+ADCIRC model is run using high-resolution computational meshes that incorporate the MBS and LBS scenarios, separately. The resulting wind and water velocities are then fed into a Lagrangian particle transport model to simulate the spill trajectories of the ASTs most likely to fail during the 250-year proxy storm. Results from this study illustrate how each storm surge mitigation strategy impacts the transport of chemical spills (modeled as Lagrangian particles) during storm surge as compared to the base case with only currently existing mitigation features in place. This study is part of a larger effort to evaluate the costs and benefits of several storm surge mitigation configurations proposed by the H-GAPS project.

Iskuulpa Watershed Management Plan : A Five-Year Plan for Protecting and Enhancing Fish and Wildlife Habitats in the Iskuulpa Watershed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Confederated Tribes of the Umatilla Indian Reservation Wildlife Program

The Confederated Tribes of the Umatilla Indian Reservation (CTUIR) propose to protect, enhance, and mitigate wildlife and wildlife habitat and watershed resources in the Iskuulpa Watershed. The Iskuulpa Watershed Project was approved as a Columbia River Basin Wildlife Fish and Mitigation Project by the Bonneville Power Administration (BPA) and Northwest Power Planning Council (NWPPC) in 1998. Iskuulpa will contribute towards meeting BPA's obligation to compensate for wildlife habitat losses resulting from the construction of the John Day and McNary Hydroelectric facilities on the Columbia River. By funding the enhancement and operation and maintenance of the Iskuulpa Watershed, BPA will receivemore » credit towards their mitigation debt. The purpose of the Iskuulpa Watershed management plan update is to provide programmatic and site-specific standards and guidelines on how the Iskuulpa Watershed will be managed over the next three years. This plan provides overall guidance on both short and long term activities that will move the area towards the goals, objectives, and desired future conditions for the planning area. The plan will incorporate managed and protected wildlife and wildlife habitat, including operations and maintenance, enhancements, and access and travel management.« less

Analysis of RFI Statistics for Aquarius RFI Detection and Mitigation Improvements

NASA Technical Reports Server (NTRS)

de Matthaeis, Paolo; Soldo, Yan; Le Vine, David M.

2016-01-01

Aquarius is an L-band active/passive sensor designed to globally map sea surface salinity from space. Two instruments, a radar scatterometer and a radiometer, observe the same surface footprint almost simultaneously. The radiometer is the primary instrument for sensing sea surface salinity (SSS), while the scatterometer is included to provide a correction for sea surface roughness, which is a primary source of error in the salinity retrieval. Although the primary objective is the measurement of SSS, the instrument combination operates continuously, acquiring data over land and sea ice as well. An important feature of the data processing includes detection and mitigation of Radio Frequency Interference (RFI) which is done separately for both active and passive instruments. Correcting for RFI is particularly critical over ocean because of the high accuracy required in the brightness temperature measurements for SSS retrieval. It is also necessary for applications of the Aquarius data over land, where man-made interference is widespread, even though less accuracy is required in this case. This paper will provide an overview of the current status of the Aquarius RFI processing and an update on the ongoing work on the improvement of the RFI detection and mitigation performance.

The 1990 update to strategy for exploration of the inner planets

NASA Technical Reports Server (NTRS)

Esposito, Larry W.; Pepin, Robert O.; Cheng, Andrew F.; Jakosky, Bruce M.; Lunine, Jonathan I.; Mcfadden, Lucy-Ann; Mckay, Christopher P.; Mckinnon, William B.; Muhleman, Duane O.; Nicholson, Philip

1990-01-01

The Committee on Planetary and Lunar Exploration (COMPLEX) has undertaken to review and revise the 1978 report Strategy for Exploration of the Inner Planets, 1977-1987. The committee has found the 1978 report to be generally still pertinent. COMPLEX therefore issues its new report in the form of an update. The committee reaffirms the basic objectives for exploration of the planets: to determine the present state of the planets and their satellites, to understand the processes active now and at the origin of the solar system, and to understand planetary evolution, including appearance of life and its relation to the chemical history of the solar system.

Treatment 2.0: catalyzing the next phase of treatment, care and support.

PubMed

Duncombe, Chris; Ball, Andrew; Passarelli, Carlos; Hirnschall, Gottfried

2013-01-01

This review provides an update on the WHO/UNAIDS Treatment 2.0 strategy by reviewing the documents and technical updates issued under the initiative. Launched in 2010, this global initiative provides a framework for the continued scale-up of access to HIV care and treatment. WHO has prioritized once daily fixed-dose combination as the preferred antiretroviral (ARV) regimen to initiate HIV treatment, paving the way for programmatic simplification, with reduced toxicity and improved adherence. WHO also recommends the use of point-of-care diagnostics, with CD4 cell count technologies being implemented in the field and progress towards improving access to simplified viral load testing. The strategy also seeks mechanisms that can contribute to reducing treatment costs, such as pooled commodity procurement and public health-oriented licensing approaches. Improved service delivery, specifically through decentralization, task shifting, integration and community mobilization also has the potential to reduce costs and improve access. Support to countries has been provided through the timely release of a series of programmatic and technical updates on specific treatment-related topics. The Treatment 2.0 strategy articulates how innovation and greater efficiency can make HIV care and treatment more accessible and affordable, and guide treatment and prevention scale-up.

Swarm intelligence inspired shills and the evolution of cooperation.

PubMed

Duan, Haibin; Sun, Changhao

2014-06-09

Many hostile scenarios exist in real-life situations, where cooperation is disfavored and the collective behavior needs intervention for system efficiency improvement. Towards this end, the framework of soft control provides a powerful tool by introducing controllable agents called shills, who are allowed to follow well-designed updating rules for varying missions. Inspired by swarm intelligence emerging from flocks of birds, we explore here the dependence of the evolution of cooperation on soft control by an evolutionary iterated prisoner's dilemma (IPD) game staged on square lattices, where the shills adopt a particle swarm optimization (PSO) mechanism for strategy updating. We demonstrate that not only can cooperation be promoted by shills effectively seeking for potentially better strategies and spreading them to others, but also the frequency of cooperation could be arbitrarily controlled by choosing appropriate parameter settings. Moreover, we show that adding more shills does not contribute to further cooperation promotion, while assigning higher weights to the collective knowledge for strategy updating proves a efficient way to induce cooperative behavior. Our research provides insights into cooperation evolution in the presence of PSO-inspired shills and we hope it will be inspirational for future studies focusing on swarm intelligence based soft control.

The Replicator Equation on Graphs

PubMed Central

Ohtsuki, Hisashi; Nowak, Martin A.

2008-01-01

We study evolutionary games on graphs. Each player is represented by a vertex of the graph. The edges denote who meets whom. A player can use any one of n strategies. Players obtain a payoff from interaction with all their immediate neighbors. We consider three different update rules, called ‘birth-death’, ‘death-birth’ and ‘imitation’. A fourth update rule, ‘pairwise comparison’, is shown to be equivalent to birth-death updating in our model. We use pair-approximation to describe the evolutionary game dynamics on regular graphs of degree k. In the limit of weak selection, we can derive a differential equation which describes how the average frequency of each strategy on the graph changes over time. Remarkably, this equation is a replicator equation with a transformed payoff matrix. Therefore, moving a game from a well-mixed population (the complete graph) onto a regular graph simply results in a transformation of the payoff matrix. The new payoff matrix is the sum of the original payoff matrix plus another matrix, which describes the local competition of strategies. We discuss the application of our theory to four particular examples, the Prisoner’s Dilemma, the Snow-Drift game, a coordination game and the Rock-Scissors-Paper game. PMID:16860343

Integrated NTP Vehicle Radiation Design

NASA Technical Reports Server (NTRS)

Caffrey, Jarvis A.; Rodriquez, Mitchell A.

2018-01-01

The development of a nuclear thermal propulsion stage requires consideration for radiation emitted from the nuclear reactor core. Applying shielding mass is an effective mitigating solution, but a better alternative is to incorporate some mitigation strategies into the propulsion stage and crew habitat. In this way, the required additional mass is minimized and the mass that must be applied may in some cases be able to serve multiple purposes. Strategies for crew compartment shielding are discussed that reduce dose from both engine and cosmic sources, and in some cases may also serve to reduce life support risks by permitting abundant water reserves. Early consideration for integrated mitigation solutions in a crewed nuclear thermal propulsion (NTP) vehicle will enable reduced radiation burden from both cosmic and nuclear sources, improved thrust-to-weight ratio or payload capacity by reducing 'dead mass' of shielding, and generally support a more robust risk posture for a NTP-powered Mars mission by permitting shorter trip times and increased water reserves.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bolan, N.A.; Hansen-Murray, C.S.; Haynes, R.W.

Implications of the interim comprehensive strategy for improved Pacific salmon and steelhead habitat management (PACFISH) were estimated for those Bureau of Land Management (BLM) districts and National Forest System (NFS) lands west of the Rocky Mountains that have anadromous fish. The physical impacts and associated mitigation costs from implementing the PACFISH strategy over the next decade in Pacific Northwest, Intermountain, Northern, Pacific Southwest, and Alaska Region National Forest and BLM district recreation, range, and timber programs were analyzed with the actual current output as the base. Economic considerations were added to evaluate any change in the perceived ranking of severitymore » among the impacts. Two cases were considered in the analyses: a derived worst case, where a total reduction of the actual current output of the programs in anadromous fishbearing drainages occurs (giving a minimum value for the programs in those drainages), and a mitigated case where all or part of the loss is mitigated and the cost of doing so is evaluated with two phases, one without economics and the other with it.« less

Integrated NTP Vehicle Radiation Design

NASA Technical Reports Server (NTRS)

Caffrey, Jarvis; Rodriquez, Mitchell

2018-01-01

The development of a nuclear thermal propulsion stage requires consideration for radiation emitted from the nuclear reactor core. Applying shielding mass is an effective mitigating solution, but a better alternative is to incorporate some mitigation strategies into the propulsion stage and crew habitat. In this way, the required additional mass is minimized and the mass that must be applied may in some cases be able to serve multiple purposes. Strategies for crew compartment shielding are discussed that reduce dose from both engine and cosmic sources, and in some cases may also serve to reduce life support risks by permitting abundant water reserves. Early consideration for integrated mitigation solutions in a crewed nuclear thermal propulsion (NTP) vehicle will enable reduced radiation burden from both cosmic and nuclear sources, improved thrust-to-weight ratio or payload capacity by reducing 'dead mass' of shielding, and generally support a more robust risk posture for a NTP-powered Mars mission by permitting shorter trip times and increased water reserves

Identification and mitigation of stray laser light in the Thomson scattering system on the Madison Symmetric Torus (MST)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jacobson, C. M., E-mail: cjacobson@wisc.edu; Borchardt, M. T.; Den Hartog, D. J.

The Thomson scattering diagnostic on the Madison Symmetric Torus (MST) records excessive levels of stray Nd:YAG laser light. Stray light saturates the 1064 nm spectral channel in all polychromators, which prevents absolute electron density measurements via Rayleigh scattering calibration. Furthermore, stray light contaminates adjacent spectral channels for r/a ≥ 0.75, which renders the diagnostic unable to make electron temperature measurements at these radii. In situ measurements of stray light levels during a vacuum vessel vent are used to identify stray light sources and strategies for reduction of stray light levels. Numerical modeling using Zemax OpticStudio supports these measurements. The modelmore » of the vacuum vessel and diagnostic includes synthetic collection optics to enable direct comparison of measured and simulated stray light levels. Modeling produces qualitatively similar stray light distributions to MST measurements, and quantifies the mitigation effects of stray light mitigation strategies prior to implementation.« less

Synthesis Guidebook. Volume 1. Methodology Definition

DTIC Science & Technology

1992-10-16

OV I. Introductiaa " Synthesis Transition Strategies (Williams 1990b), which discusses a strategy for the incremental transitioning of Synthesis into... strategies for mitigating those risks. Use checkpoints, reviews, and metrics to reveal flaws and misconceptions. 4. Interaction With Other Activities... markets and customer requirements lead to evolving product and process needs of Application Engineering projects. OV2-5 OV.2. Fundamentals of Synthesis

Economic resilience lessons from the ShakeOut earthquake scenario

USGS Publications Warehouse

Wein, A.; Rose, A.

2011-01-01

Following a damaging earthquake, “business interruption” (BI)—reduced production of goods and services—begins and continues long after the ground shaking stops. Economic resilience reduces BI losses by making the best use of the resources available at a given point in time (static resilience) or by speeding recovery through repair and reconstruction (dynamic resilience), in contrast to mitigation that prevents damage in the first place. Economic resilience is an important concept to incorporate into economic loss modeling and in recovery and contingency planning. Economic resilience framework includes the applicability of resilience strategies to production inputs and output, demand- and supply-side effects, inherent and adaptive abilities, and levels of the economy. We use our resilience framework to organize and share strategies that enhance economic resilience, identify overlooked resilience strategies, and present evidence and structure of resilience strategies for economic loss modelers. Numerous resilience strategies are compiled from stakeholder discussions about the ShakeOut Scenario (Jones et. al. 2008). Modeled results of ShakeOut BI sector losses reveal variable effectiveness of resilience strategies for lengthy disruptions caused by fire-damaged buildings and water service outages. Resilience is a complement to mitigation and may, in fact, have cost and all-hazards advantages.

Factors Influencing the Decision to Proceed to Firmware Upgrades to Implanted Pacemakers for Cybersecurity Risk Mitigation.

PubMed

Saxon, Leslie A; Varma, Niraj; Epstein, Laurence M; Ganz, Leonard I; Epstein, Andrew E

2018-05-10

In August 2017, the first major recall for cybersecurity vulnerabilities in pacemakers capable of remote connectivity was released that impacted 465,000 United States patients. 1,2 The FDA approved a firmware update designed by the manufacturer of the devices as a remediation (Abbott , formally St. Jude Medical). The recall was in response to the public disclosure of vulnerability by an investment firm and produced in a lab environment that could allow an unauthorized party in close proximity to a patient to impact the performance of the device or modify device settings via radio frequency communication. 3 While an exploit has not occurred in a patient and requires a high degree of resources and skill to execute, if accomplished, it could pose a significant risk to device safety and essential performance and cause patient harm. The FDA defines this as an uncontrolled vulnerability. 2 The recall recommendations were coordinated between the FDA, the Industrial Control Systems Cyber Emergency Response Team (ICS-CERT), a division of Homeland Security that responds to and coordinates disclosure of critical infrastructure cybersecurity vulnerabilities and Abbott. 1 All parties urged caution and shared decision making between patient and clinician as to whether to have the device firmware update, a process that requires a clinic visit to implement with a device programmer. The manufacturer bench tested the firmware update but the only prior experience with an implanted device firmware updates was a 2012 ICD firmware update that demonstrated a 0.197% risk of device back-up mode pacing after the upgrade was performed.

Calibrating random forests for probability estimation.

PubMed

Dankowski, Theresa; Ziegler, Andreas

2016-09-30

Probabilities can be consistently estimated using random forests. It is, however, unclear how random forests should be updated to make predictions for other centers or at different time points. In this work, we present two approaches for updating random forests for probability estimation. The first method has been proposed by Elkan and may be used for updating any machine learning approach yielding consistent probabilities, so-called probability machines. The second approach is a new strategy specifically developed for random forests. Using the terminal nodes, which represent conditional probabilities, the random forest is first translated to logistic regression models. These are, in turn, used for re-calibration. The two updating strategies were compared in a simulation study and are illustrated with data from the German Stroke Study Collaboration. In most simulation scenarios, both methods led to similar improvements. In the simulation scenario in which the stricter assumptions of Elkan's method were not met, the logistic regression-based re-calibration approach for random forests outperformed Elkan's method. It also performed better on the stroke data than Elkan's method. The strength of Elkan's method is its general applicability to any probability machine. However, if the strict assumptions underlying this approach are not met, the logistic regression-based approach is preferable for updating random forests for probability estimation. © 2016 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd. © 2016 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.

A Distributed Cache Update Deployment Strategy in CDN

NASA Astrophysics Data System (ADS)

E, Xinhua; Zhu, Binjie

2018-04-01

The CDN management system distributes content objects to the edge of the internet to achieve the user's near access. Cache strategy is an important problem in network content distribution. A cache strategy was designed in which the content effective diffusion in the cache group, so more content was storage in the cache, and it improved the group hit rate.

Anti-Drug Abuse Strategy Report. State of New York. 1990 Update.

ERIC Educational Resources Information Center

New York Governor's Office, Albany. Statewide Anti-Drug Abuse Council.

This annual report from the Statewide Anti-Drug Abuse Council of New York proposes strategies for the coming year. Ongoing support for the state and local law enforcement efforts is reaffirmed as a vital component of the strategy. The council promotes a strengthening of their commitment and focus on severely impacted populations, integration of…

Strategies for Addressing Asthma within a Coordinated School Health Program, with Updated Resources. Revised

ERIC Educational Resources Information Center

Centers for Disease Control and Prevention, 2006

2006-01-01

This publication offers concrete suggestions for schools working to improve the health and school attendance of students with asthma. The Centers for Disease Control and Prevention (CDC) has identified six strategies for schools and districts to consider when addressing asthma within a coordinated school health program. The six strategies detailed…

Cutting through the Hype: The Essential Guide to School Reform. Revised, Expanded, and Updated Edition

ERIC Educational Resources Information Center

David, Jane L.; Cuban, Larry

2010-01-01

"Cutting Through the Hype: The Essential Guide to School Reform" is a revised, expanded, and updated version of the classic work by Jane L. David and Larry Cuban. It offers balanced analyses of 23 currently popular school reform strategies, from teacher performance pay and putting mayors in charge to turnaround schools and data-driven instruction.…

Development of interim oak assessment guidelines for the silvah decision-support system

Treesearch

Patrick H. Brose

2007-01-01

Updates to the SILVAH decision-support system make it more applicable to the mixed oak forests of Pennsylvania and other mid-Atlantic states. This update required establishing interim inventory guidelines for assessing the competitive ability of advance oak regeneration. This assessment was complicated by oak’s growth strategy, emphasizing root development in lieu of...

Realistic decision-making processes in a vaccination game

NASA Astrophysics Data System (ADS)

Iwamura, Yoshiro; Tanimoto, Jun

2018-03-01

Previous studies of vaccination games have nearly always assumed a pairwise comparison between a focal and neighboring player for the strategy updating rule, which comes from numerous compiled studies on spatial versions of 2-player and 2-strategy (2 × 2) games such as the spatial prisoner's dilemma (SPD). We propose, in this study, new update rules because the human decision-making process of whether to commit to a vaccination is obviously influenced by a "sense of crisis" or "fear" urging him/her toward vaccination, otherwise they will likely be infected. The rule assumes that an agent evaluates whether getting a vaccination or trying to free ride should be attempted based on observations of whether neighboring non-vaccinators were able to successfully free ride during the previous time-step. Compared to the conventional updating rule (standard pairwise comparison assuming a Fermi function), the new rules generally realize higher vaccination coverage and smaller final epidemic sizes. One rule in particular shows very good performance with significantly smaller epidemic sizes despite comparable levels of vaccination coverage. This is because the specific update rule helps vaccinators spread widely in the domain, which effectively hampers the spread of epidemics.

Sequential updating of multimodal hydrogeologic parameter fields using localization and clustering techniques

NASA Astrophysics Data System (ADS)

Sun, Alexander Y.; Morris, Alan P.; Mohanty, Sitakanta

2009-07-01

Estimated parameter distributions in groundwater models may contain significant uncertainties because of data insufficiency. Therefore, adaptive uncertainty reduction strategies are needed to continuously improve model accuracy by fusing new observations. In recent years, various ensemble Kalman filters have been introduced as viable tools for updating high-dimensional model parameters. However, their usefulness is largely limited by the inherent assumption of Gaussian error statistics. Hydraulic conductivity distributions in alluvial aquifers, for example, are usually non-Gaussian as a result of complex depositional and diagenetic processes. In this study, we combine an ensemble Kalman filter with grid-based localization and a Gaussian mixture model (GMM) clustering techniques for updating high-dimensional, multimodal parameter distributions via dynamic data assimilation. We introduce innovative strategies (e.g., block updating and dimension reduction) to effectively reduce the computational costs associated with these modified ensemble Kalman filter schemes. The developed data assimilation schemes are demonstrated numerically for identifying the multimodal heterogeneous hydraulic conductivity distributions in a binary facies alluvial aquifer. Our results show that localization and GMM clustering are very promising techniques for assimilating high-dimensional, multimodal parameter distributions, and they outperform the corresponding global ensemble Kalman filter analysis scheme in all scenarios considered.

Contamination Detection and Mitigation Strategies for Unsymmetric Dimethylhydrazine/Nitrogen Tetroxide Non-Combustion Product Residues

NASA Technical Reports Server (NTRS)

Greene, Benjamin; Buchanan, Vanessa D.; Baker, David L.

2006-01-01

Dimethylamine and nitrite, which are non-combustion reaction products of unsymmetrical dimethylhydrazine (UDMH) and nitrogen tetroxide (NTO) propellants, can contaminate spacesuits during extra-vehicular activity (EVA) operations. They can react with water in the International Space Station (ISS) airlock to form N-nitrosodimethylamine (NDMA), a carcinogen. Detection methods for assessing nitrite and dimethylamine contamination were investigated. The methods are based on color-forming reactions in which intensity of color is proportional to concentration. A concept color detection kit using a commercially available presumptive field test for methamphetamine coupled with nitrite test strips was developed and used to detect dimethylamine and nitrite. Contamination mitigation strategies were also developed.

Mitigation Strategies To Protect Food Against Intentional Adulteration. Final rule.

PubMed

2016-05-27

The Food and Drug Administration (FDA or we) is issuing this final rule to require domestic and foreign food facilities that are required to register under the Federal Food, Drug, and Cosmetic Act (the FD&C Act) to address hazards that may be introduced with the intention to cause wide scale public health harm. These food facilities are required to conduct a vulnerability assessment to identify significant vulnerabilities and actionable process steps and implement mitigation strategies to significantly minimize or prevent significant vulnerabilities identified at actionable process steps in a food operation. FDA is issuing these requirements as part of our implementation of the FDA Food Safety Modernization Act (FSMA).

3 CFR - Implementation of the National HIV/AIDS Strategy

Code of Federal Regulations, 2011 CFR

2011-01-01

... status updates on achieving specific quantitative targets established by the Strategy, with relevant...-departmental coordination and collaboration on HIV/AIDS care, research, and prevention services. (b... and research priorities in the areas of highest impact. (c) Presidential Advisory Council on HIV/AIDS...

Seat vibration in military propeller aircraft: characterization, exposure assessment, and mitigation.

PubMed

Smith, Suzanne D

2006-01-01

There have been increasing reports of annoyance, fatigue, and even neck and back pain during prolonged operation of military propeller aircraft, where persistent multi-axis vibration occurs at higher frequencies beyond human whole-body resonance. This paper characterizes and assesses the higher frequency vibration transmitted to the occupants onboard these aircraft. Multi-axis accelerations were measured at the occupied seating surfaces onboard the WC/C-130J, C-130H3, and E-2C Hawkeye. The effects of the vibration were assessed in accordance with current international guidelines (ISO 2631-1:1997). The relative psychophysical effects of the frequency components and the effects of selected mitigation strategies were also investigated. The accelerations associated with the blade passage frequency measured on the passenger seat pans located on the side of the fuselage near the propeller plane of the C-130J (102 Hz) and C-130H3 (68 Hz) were noteworthy (5.19 +/- 1.72 ms(-2) rms and 7.65 +/- 0.71 ms(-2) rms, respectively, in the lateral direction of the aircraft). The psychophysical results indicated that the higher frequency component would dominate the side passengers' perception of the vibration. Balancing the props significantly reduced the lower frequency propeller rotation vibration (17 Hz), but had little effect on the blade passage frequency vibration. The relationships among the frequency, vibration direction, and seat measurement sites were complex, challenging the development of seating systems and mitigation strategies. Psychophysical metrics could provide a tool for optimizing mitigation strategies, but the current international vibration standard may not provide optimum assessment methods for evaluating higher frequency operational exposures.

Managing conflict between large carnivores and livestock.

PubMed

van Eeden, Lily M; Crowther, Mathew S; Dickman, Chris R; Macdonald, David W; Ripple, William J; Ritchie, Euan G; Newsome, Thomas M

2018-02-01

Large carnivores are persecuted globally because they threaten human industries and livelihoods. How this conflict is managed has consequences for the conservation of large carnivores and biodiversity more broadly. Mitigating human-predator conflict should be evidence-based and accommodate people's values while protecting carnivores. Despite much research into human and large-carnivore coexistence strategies, there have been few attempts to document the success of conflict-mitigation strategies on a global scale. We conducted a meta-analysis of global research on conflict mitigation related to large carnivores and humans. We focused on conflicts that arise from the threat large carnivores pose to livestock. We first used structured and unstructured searching to identify replicated studies that used before-after or control-impact design to measure change in livestock loss as a result of implementing a management intervention. We then extracted relevant data from these studies to calculate an overall effect size for each intervention type. Research effort and focus varied among continents and aligned with the histories and cultures that shaped livestock production and attitudes toward carnivores. Livestock guardian animals most effectively reduced livestock losses. Lethal control was the second most effective control, although its success varied the most, and guardian animals and lethal control did not differ significantly. Financial incentives have promoted tolerance of large carnivores in some settings and reduced retaliatory killings. We suggest coexistence strategies be location-specific, incorporate cultural values and environmental conditions, and be designed such that return on financial investment can be evaluated. Improved monitoring of mitigation measures is urgently required to promote effective evidence-based policy. © 2017 Society for Conservation Biology.

Sarcococca blight: Use of whole genome sequencing as a strategy for fungal disease diagnosis

USDA-ARS?s Scientific Manuscript database

Early and accurate diagnosis of new plant pathogens is vital for the rapid implementation of effective mitigation strategies and appropriate regulatory responses. Most commonly, pathogen identification relies on morphology and DNA marker analysis. However, for new diseases, these approaches may not...

Working to Reduce the Effects of Discrimination: Identity Management Strategies in Organizations

ERIC Educational Resources Information Center

Shih, Margaret; Young, Maia J.; Bucher, Amy

2013-01-01

Despite efforts to dispel discrimination, workplace discrimination still occurs. We introduce two classes of identity management strategies individuals use to mitigate the negative consequences of discrimination: identity switching (i.e., deemphasizing target identities and recategorizing to a more positively valued identity) and identity…

78 FR 79469 - Strategies To Address Hemolytic Complications of Immune Globulin Infusions; Public Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-30

...] Strategies To Address Hemolytic Complications of Immune Globulin Infusions; Public Workshop AGENCY: Food and... Infusions.'' The purpose of the public workshop is to identify and discuss potential risk mitigation...) (Human) infusion. Complications of hemolysis include severe anemia requiring transfusion, renal failure...

Updated Status and Performance at the Fourth HST COS FUV Lifetime Position

NASA Astrophysics Data System (ADS)

Taylor, Joanna M.; De Rosa, Gisella; Fix, Mees B.; Fox, Andrew; Indriolo, Nick; James, Bethan; Jedrzejewski, Robert I.; Oliveira, Cristina M.; Penton, Steven V.; Plesha, Rachel; Proffitt, Charles R.; Rafelski, Marc; Roman-Duval, Julia; Sahnow, David J.; Snyder, Elaine M.; Sonnentrucker, Paule; White, James

2017-06-01

To mitigate the adverse effects of gain sag on the spectral quality and accuracy of Hubble Space Telescope’s Cosmic Origins Spectrograph FUV observations, COS FUV spectra will be moved from Lifetime Position 3 (LP3) to a new pristine location on the detectors at LP4 in July 2017. To achieve maximal spectral resolution while preserving detector area, the spectra will be shifted in the cross-dispersion (XD) direction by -2.5" (about -31 pixels) from LP3 or -5” (about 62 pixels) from the original LP1. At LP4, the wavelength calibration lamp spectrum can overlap with the previously gain-sagged LP2 PSA spectrum location. If lamp lines fall in the gain sag holes from LP2, it can cause line ratios to change and the wavelength calibration to fail. As a result, we have updated the Wavecal Parameters Reference Table and CalCOS to address this issue. Additionally, it was necessary to extend the current geometric correction in order to encompass the entire LP4 location. Here we present 2-D template profiles and 1-D spectral trace centroids derived at LP4 as well as LP4-related updates to the wavelength calibration, and geometric correction.

Politics and abortion in Bulgaria.

PubMed

Sirakova, K

1992-01-01

Political change in Bulgaria has meant the beginning of the recognition of the reproduction rights of women. Abortion, for example, was legalized in 1990. Women in Bulgaria, however, still lack the information they need on basic hygiene and sex. It is impossible to promulgate a progressive strategy in Bulgaria if one ignores the isolation of the Turkish and Gypsy ethnic communities. In addition, an economic crisis exists, and no real measures have been undertaken to mitigate the situation. The new democratic institutions have settled comfortably into the structures of the former communist rule, even to the point of adopting the same extensive demagogic terminology which perpetrates the old gap between words and deeds. For example, although a new birth control strategy and plan for sex education was announced 2 years ago, nothing definite has been done. One development, however, has been the legalization of abortion, which was accompanied by an immediate drop in the abortion rate (still 1.5 abortions/birth). Because of a lack of sex education, 900 children are born to girls under age 15 each year. Bulgaria is just starting to embrace modern values and must update its attitudes towards women. Bulgaria's formal institutions seem to be unable to face this issue, and many societies and foundations have emerged to work for women's rights, to protect out-of-wedlock children, and to fight disease (including AIDS) and drug addiction. However, these organizations are not producing real results and are simply providing shelter to representatives of the old nomenclature. Real efforts to overcome these problems will continue despite the current discouraging state of affairs.

Integrating diet and exercise into care of prostate cancer patients on androgen deprivation therapy

PubMed Central

Moyad, Mark A; Newton, Robert U; Tunn, Ulf W; Gruca, Damian

2016-01-01

Improved diagnosis and treatment regimens have resulted in greater longevity for men with prostate cancer. This has led to an increase in both androgen deprivation therapy (ADT) use and duration of exposure, and therefore to its associated adverse effects, such as sexual dysfunction, osteoporosis, reduced muscle mass, increased fat mass, and increased incidence of cardiovascular disease and type 2 diabetes. Given that the adverse effects of ADT are systemic, often debilitating, and difficult to treat, efforts continue in the development of new strategies for long-term management of prostate cancer. The PubMed database was searched to select trials, reviews, and meta-analyses in English using such search terms as “prostate cancer” and “androgen deprivation therapy”, “cardiovascular risk”, “lean body mass”, “exercise”, and “diet”. The initial searches produced 379 articles with dates 2005 or more recent. Articles published after 2004 were favored. This review utilizes the latest data to provide a status update on the effects of exercise and diet on patients with prostate cancer, focusing on ADT-associated side effects, and it discusses the evidence for such interventions. Since the evidence of large-scale trials in patients with prostate cancer is missing, and an extrapolation of supporting data to all patient subgroups cannot be provided, individualized risk assessments remain necessary before the initiation of exercise and diet programs. Exercise, diet, and nutritional supplementation interventions have the potential to provide effective, accessible, and relatively inexpensive strategies for mitigating ADT-associated toxicities without introducing additional adverse effects. PMID:27574584

Identification of Modeling Approaches To Support Common-Cause Failure Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korsah, Kofi; Wood, Richard Thomas

2015-06-01

Experience with applying current guidance and practices for common-cause failure (CCF) mitigation to digital instrumentation and control (I&C) systems has proven problematic, and the regulatory environment has been unpredictable. The impact of CCF vulnerability is to inhibit I&C modernization and, thereby, challenge the long-term sustainability of existing plants. For new plants and advanced reactor concepts, the issue of CCF vulnerability for highly integrated digital I&C systems imposes a design burden resulting in higher costs and increased complexity. The regulatory uncertainty regarding which mitigation strategies are acceptable (e.g., what diversity is needed and how much is sufficient) drives designers to adoptmore » complicated, costly solutions devised for existing plants. The conditions that constrain the transition to digital I&C technology by the U.S. nuclear industry require crosscutting research to resolve uncertainty, demonstrate necessary characteristics, and establish an objective basis for qualification of digital technology for usage in Nuclear Power Plant (NPP) I&C applications. To fulfill this research need, Oak Ridge National Laboratory is conducting an investigation into mitigation of CCF vulnerability for nuclear-qualified applications. The outcome of this research is expected to contribute to a fundamentally sound, comprehensive technical basis for establishing the qualification of digital technology for nuclear power applications. This report documents the investigation of modeling approaches for representing failure of I&C systems. Failure models are used when there is a need to analyze how the probability of success (or failure) of a system depends on the success (or failure) of individual elements. If these failure models are extensible to represent CCF, then they can be employed to support analysis of CCF vulnerabilities and mitigation strategies. Specifically, the research findings documented in this report identify modeling approaches that can be adapted to contribute to the basis for developing systematic methods, quantifiable measures, and objective criteria for evaluating CCF vulnerabilities and mitigation strategies.« less

Advance strategy for climate change adaptation and mitigation in cities

NASA Astrophysics Data System (ADS)

Varquez, A. C. G.; Kanda, M.; Darmanto, N. S.; Sueishi, T.; Kawano, N.

2017-12-01

An on-going 5-yr project financially supported by the Ministry of Environment, Japan, has been carried out to specifically address the issue of prescribing appropriate adaptation and mitigation measures to climate change in cities. Entitled "Case Study on Mitigation and Local Adaptation to Climate Change in an Asian Megacity, Jakarta", the project's relevant objectives is to develop a research framework that can consider both urbanization and climate change with the main advantage of being readily implementable for all cities around the world. The test location is the benchmark city, Jakarta, Indonesia, with the end focus of evaluating the benefits of various mitigation and adaptation strategies in Jakarta and other megacities. The framework was designed to improve representation of urban areas when conducting climate change investigations in cities; and to be able to quantify separately the impacts of urbanization and climate change to all cities globally. It is comprised of a sophisticated, top-down, multi-downscaling approach utilizing a regional model (numerical weather model) and a microscale model (energy balance model and CFD model), with global circulation models (GCM) as input. The models, except the GCM, were configured to reasonably consider land cover, urban morphology, and anthropogenic heating (AH). Equally as important, methodologies that can collect and estimate global distribution of urban parametric and AH datasets are continually being developed. Urban growth models, climate scenario matrices that match representative concentration pathways with shared socio-economic pathways, present distribution of socio-demographic indicators such as population and GDP, existing GIS datasets of urban parameters, are utilized. From these tools, future urbanization (urban morphological parameters and AH) can be introduced into the models. Sensitivity using various combinations of GCM and urbanization can be conducted. Furthermore, since the models utilize parameters that can be readily modified to suit certain countermeasures, adaptation and mitigation strategies can be evaluated using thermal comfort and other social indicators. With the approaches introduced through this project, a deeper understanding of urban-climate interactions in the changing global climate can be achieved.

Novel Cooling Strategies for Military Training and Operations.

PubMed

Lee, Jason K W; Kenefick, Robert W; Cheuvront, Samuel N

2015-11-01

The deleterious effects of environmental heat stress, combined with high metabolic loads and protective clothing and equipment of the modern Warfighter, impose severe heat strain, impair task performance, and increase risk of heat illness, thereby reducing the chance for mission success. Despite the implementation of heat-risk mitigation procedures over the past decades, task performance still suffers and exertional heat illness remains a major military problem. We review 3 novel heat mitigation strategies that may be implemented in the training or operational environment to reduce heat strain and the risk of exertional heat illness. These strategies include ingestion of ice slurry, arm immersion cooling, and microclimate cooling. Each of these strategies is suitable for use in different scenarios and the choice of cooling strategy is contingent on the requirements, circumstances, and constraints of the training and operational scenario. Ingestion of ice slurry and arm immersion cooling are practical strategies that may be implemented during training scenarios; ice slurry can be ingested before and during exercise, whereas arm immersion cooling can be administered after exercise-heat exposure. In the operational environment, existing microclimate cooling can be implemented with retrofitted vehicles and as an unmounted system, and it has the potential for use in many military occupational scenarios. This review will discuss the efficacy, limitations, and practical considerations for field implementation of each strategy.

A decentralized charging control strategy for plug-in electric vehicles to mitigate wind farm intermittency and enhance frequency regulation

NASA Astrophysics Data System (ADS)

Luo, Xiao; Xia, Shiwei; Chan, Ka Wing

2014-02-01

This paper proposes a decentralized charging control strategy for a large population of plug-in electric vehicles (PEVs) to neutralize wind power fluctuations so as to improve the regulation of system frequency. Without relying on a central control entity, each PEV autonomously adjusts its charging or discharging power in response to a communal virtual price signal and based on its own urgency level of charging. Simulation results show that under the proposed charging control, the aggregate PEV power can effectively neutralize wind power fluctuations in real-time while differential allocation of neutralization duties among the PEVs can be realized to meet the PEV users' charging requirements. Also, harmful wind-induced cyclic operations in thermal units can be mitigated. As shown in economic analysis, the proposed strategy can create cost saving opportunities for both PEV users and utility.