Frequency and topography of small cerebrovascular lesions in vascular and in mixed dementia: a post-mortem 7-tesla magnetic resonance imaging study with neuropathological correlates.

PubMed

De Reuck, Jacques; Auger, Florent; Durieux, Nicolas; Deramecourt, Vincent; Maurage, Claude-Alain; Cordonnier, Charlotte; Pasquier, Florence; Leys, Didier; Bordet, Regis

2017-01-01

Introduction: Mixed dementia (MixD) refers to a combination of definite Alzheimer's disease (AD) and vascular encephalopathy. The existence of a "pure" type of vascular dementia (VaD) is controversial. There is a need to find magnetic resonance imaging (MRI) characteristics allowing the distinction between VaD and MixD. The present post-mortem 7.0-tesla MRI compares the frequency or severity and the topography of the small cerebrovascular lesions in brains of patients with VaD and with MixD. Material and methods: Based on neuropathological criteria, 14 brains were classified as VaD, 24 as MixD and 11 as controls. Three coronal sections of a cerebral hemisphere and a horizontal section of a cerebellar hemisphere underwent T2 and T2* 7.0-tesla MRI examination. The mean values and topographic distribution of white matter changes (WMCs), lacunar infarcts (LIs), cortical microbleeds (CoMBs) and cortical microinfarcts (CoMIs) were determined and compared between the different groups. Results: Compared to the controls, both VaD and MixD brains had significantly more severe WMCs and increased numbers of CoMBs and CoMIs. Lacunar infarcts predominated only in the VaD cases. On mutual comparison of VaD and MixD brains, CoMBs and CoMIs predominated in the frontal lobe and the cerebellum of VaD, while were mainly present in the occipital lobe of MixD. White matter changes predominated in the temporal lobe of MixD cases. Lacunar infarcts were significantly increased in the corona radiata and putamen of VaD patients. Conclusions: The present post-mortem MRI study shows clear differences in the distribution and the types of cerebrovascular lesions on high-field MRI, confirming that VaD and MixD are different diseases. .

Mixed vitiligo of Blaschko lines: a newly discovered presentation of vitiligo responsive to combination treatment.

PubMed

Kovacevic, Maja; Stanimirovic, Andrija; Vucic, Majda; Goren, Andy; Situm, Mirna; Lukinovic Skudar, Vesna; Lotti, Torello

2016-07-01

Vitiligo, depigmenting disorder of the skin and mucous membranes, affects up to 1% of the population worldwide. It is classified into four major types: segmental, non-segmental, mixed, and unclassified type. Non-segmental vitiligo refers to non-dermatomal distribution of lesions, while dermatomal distribution of lesions is present in patients with segmental vitiligo. Segmental vitiligo can also follow Blaschko lines - pathways of epidermal cell migration and proliferation during the development of the fetus. Here, we present patient with segmental and non-segmental vitiligo following Blaschko lines with excellent therapeutic response to combined therapy. Prior to our report, a case of segmental and non-segmental vitiligo followed by Blaschko lines was never described, therefore we suggest the term "mixed vitiligo of Blaschko lines" to describe this entity. This is also a rare case in which 90% repigmentation was achieved in patient with segmental and nonsegmental vitiligo following Blaschko lines in only 2 months of combined therapy. © 2016 Wiley Periodicals, Inc.

Malignant mixed germ cell tumour of ovary--an unusual combination and review of literature.

PubMed

Goyal, Lajya Devi; Kaur, Sharanjit; Kawatra, Kanwardeep

2014-11-04

Mixed germ cell tumours of the ovary are malignant neoplasms of the ovary comprising of two or more types of germ cell components. Most of the malignant mixed germ cell tumours consists of dysgerminoma accompanied by endodermal sinus tumours, immature teratoma or choriocarcinoma. There are only few case reports of mixed germ cell tumours with different combinations of malignant components. We report a very rare case of mixed germ cell tumours consisted of malignant components of endodermal sinus tumour, emryonal carcinoma, and benign component of teratomatuos and trophoblastic differentiation. This is the first case report in the literature with both benign and malignant component of type described to best of our knowledge. Patient was an 18 year old girl, who presented with pain abdomen, abdominal mass and irregular bleeding. Ultrasound and CT scan showed a huge mass with solid and cystic component. Tumour markers i.e alpha feto- protein (AFP), human chorionic gonadotropin (hCG), lactate dehydrogenate (LDH) and Ca-125 were raised. We performed fertility sparing surgery by preserving one ovary, tube and uterus. Conclusion: Malingnant mixed germ cell tumours of ovary are highly aggressive neoplasm and early intervention and fertility sparing surgery is required for any adolescent girl presenting with rapidly enlarging pelvic mass.

Evaluation and improvement of micro-surfacing mix design method and modelling of asphalt emulsion mastic in terms of filler-emulsion interaction

NASA Astrophysics Data System (ADS)

Robati, Masoud

This Doctorate program focuses on the evaluation and improving the rutting resistance of micro-surfacing mixtures. There are many research problems related to the rutting resistance of micro-surfacing mixtures that still require further research to be solved. The main objective of this Ph.D. program is to experimentally and analytically study and improve rutting resistance of micro-surfacing mixtures. During this Ph.D. program major aspects related to the rutting resistance of micro-surfacing mixtures are investigated and presented as follow: 1) evaluation of a modification of current micro-surfacing mix design procedures: On the basis of this effort, a new mix design procedure is proposed for type III micro-surfacing mixtures as rut-fill materials on the road surface. Unlike the current mix design guidelines and specification, the new mix design is capable of selecting the optimum mix proportions for micro-surfacing mixtures; 2) evaluation of test methods and selection of aggregate grading for type III application of micro-surfacing: Within the term of this study, a new specification for selection of aggregate grading for type III application of micro-surfacing is proposed; 3) evaluation of repeatability and reproducibility of micro-surfacing mixture design tests: In this study, limits for repeatability and reproducibility of micro-surfacing mix design tests are presented; 4) a new conceptual model for filler stiffening effect on asphalt mastic of micro-surfacing: A new model is proposed, which is able to establish limits for minimum and maximum filler concentrations in the micro-surfacing mixture base on only the filler important physical and chemical properties; 5) incorporation of reclaimed asphalt pavement and post-fabrication asphalt shingles in micro-surfacing mixture: The effectiveness of newly developed mix design procedure for micro-surfacing mixtures is further validated using recycled materials. The results present the limits for the use of RAP and RAS amount in micro-surfacing mixtures; 6) new colored micro-surfacing formulations with improved durability and performance: The significant improvement of around 45% in rutting resistance of colored and conventional micro-surfacing mixtures is achieved through employing low penetration grade bitumen polymer modified asphalt emulsion stabilized using nanoparticles.

Investigation of the Electron Acceleration by a High-Power Laser and a Density-Tapered Mixed-Gas Cell

NASA Astrophysics Data System (ADS)

Kim, Jinju; Phung, Vanessa L. J.; Kim, Minseok; Hur, Min-Sup; Suk, Hyyong

2017-10-01

Plasma-based accelerators can generate about 1000 times stronger acceleration field compared with RF-based conventional accelerators, which can be done by high power laser and plasma. There are many issues in this research and one of them is development of a good plasma source for higher electron beam energy. For this purpose, we are investigating a special type of plasma source, which is a density-tapered gas cell with a mixed-gas for easy injection. By this type of special gas cell, we expect higher electron beam energies with easy injection in the wakefield. In this poster, some experimental results for electron beam generation with the density-tapered mixed-gas cell are presented. In addition to the experimental results, CFD (Computational-Fluid-Dynamics) and PIC (Particle-In-Cell) simulation results are also presented for comparison studies.

Separating Dust Mixtures and Other External Aerosol Mixtures Using Airborne High Spectral Resolution Lidar Data

NASA Astrophysics Data System (ADS)

Burton, S. P.; Ferrare, R. A.; Vaughan, M.; Hostetler, C. A.; Rogers, R. R.; Hair, J. W.; Cook, A. L.; Harper, D. B.

2013-12-01

Knowledge of aerosol type is important for source attribution and for determining the magnitude and assessing the consequences of aerosol radiative forcing. The NASA Langley Research Center airborne High Spectral Resolution Lidar (HSRL-1) has acquired considerable datasets of both aerosol extensive parameters (e.g. aerosol optical depth) and intensive parameters (e.g. aerosol depolarization ratio, lidar ratio) that can be used to infer aerosol type. An aerosol classification methodology has been used extensively to classify HSRL-1 aerosol measurements of different aerosol types including dust, smoke, urban pollution, and marine aerosol. However, atmospheric aerosol is frequently not a single pure type, but instead occurs as a mixture of types, and this mixing affects the optical and radiative properties of the aerosol. Here we present a comprehensive and unified set of rules for characterizing external mixtures using several key aerosol intensive parameters: extinction-to-backscatter ratio (i.e. lidar ratio), backscatter color ratio, and depolarization ratio. Our mixing rules apply not just to the scalar values of aerosol intensive parameters, but to multi-dimensional normal distributions with variance in each measurement dimension. We illustrate the applicability of the mixing rules using examples of HSRL-1 data where mixing occurred between different aerosol types, including advected Saharan dust mixed with the marine boundary layer in the Caribbean Sea and locally generated dust mixed with urban pollution in the Mexico City surroundings. For each of these cases we infer a time-height cross section of mixing ratio along the flight track and we partition aerosol extinction into portions attributed to the two pure types. Since multiple aerosol intensive parameters are measured and included in these calculations, the techniques can also be used for cases without significant depolarization (unlike similar work by earlier researchers), and so a third example of a mixture of smoke plus marine aerosol is also explored.

Trial type mixing substantially reduces the response set effect in the Stroop task.

PubMed

Hasshim, Nabil; Parris, Benjamin A

2017-03-20

The response set effect refers to the finding that an irrelevant incongruent colour-word produces greater interference when it is one of the response options (referred to as a response set trial), compared to when it is not (a non-response set trial). Despite being a key effect for models of selective attention, the magnitude of the effect varies considerably across studies. We report two within-subjects experiments that tested the hypothesis that presentation format modulates the magnitude of the response set effect. Trial types (e.g. response set, non-response set, neutral) were either presented in separate blocks (pure) or in blocks containing trials from all conditions presented randomly (mixed). In the first experiment we show that the response set effect is substantially reduced in the mixed block context as a result of a decrease in RTs to response set trials. By demonstrating the modulation of the response set effect under conditions of trial type mixing we present evidence that is difficult for models of the effect based on strategic, top-down biasing of attention to explain. In a second experiment we tested a stimulus-driven account of the response set effect by manipulating the number of colour-words that make up the non-response set of distractors. The results show that the greater the number of non-response set colour concepts, the smaller the response set effect. Alternative accounts of the data and its implications for research debating the automaticity of reading are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

Mineral textures in Serpentine-hosted Alkaline Springs from the Oman ophiolite

NASA Astrophysics Data System (ADS)

Giampouras, Manolis; Garcia-Ruiz, Juan Manuel; Bach, Wolfgang; Garrido, Carlos J.; Los, Karin; Fussmann, Dario; Monien, Monien

2017-04-01

Meteoric water infiltration in ultramafic rocks leads to serpentinization and the formation of subaerial, low temperature, hydrothermal alkaline springs. Here, we present a detailed investigation of the mineral precipitation mechanisms and textural features of mineral precipitates, along as the geochemical and hydrological characterization, of two alkaline spring systems in the Semail ophiolite (Nasif and Khafifah sites, Wadi Tayin massif). The main aim of the study is to provide new insights into mineral and textural variations in active, on-land, alkaline vents of the Oman ophiolite. Discharge of circulating fluids forms small-scale, localized hydrological catchments consisting in unevenly interconnected ponds. Three different types of waters can be distinguished within the pond systems: i) Mg-type; alkaline (7.9 < pH < 9.5), Mg-HCO3-rich waters; ii) Ca-type; hyper-alkaline (pH > 11.6), Ca-OH-rich waters; and iii) Mix-type waters arising from the mixing of Mg-type and Ca-type waters (9.6 < pH < 11.5). Phreeqc geochemical speciation software was used to determine the saturation state and the relationship between the theoretical supersaturation (S) and rate of supersaturation (S˚ ) of solid phases. Simple mixing models using Phreeqc MIX_code revealed good mixing correlation (R2 ≥0.93) between measured and predicted values for K, Na, Cl, Mg and sulphate. Al, Ca, Si, Ba, Sr and TIC showed poorer correlations. Mineral and textural characterization from different types of water and individual ponds were carried out by X-ray diffraction (XRD), Raman spectroscopy and field-emission scanning electron microscopy coupled to dispersive energy spectroscopy (FE-SEM-EDS). Aragonite and calcite are the dominant minerals (95 vol.%) of the total mineralogical index in all sites. Mg-type waters host hydrated magnesium carbonates (nesquehonite) and magnesium hydroxycarbonate hydrates (artinite) due to evaporation. Brucite, hydromagnesite and dypingite presence in Mix-type waters is spatially controlled by the hydrology of the system and is localized around mixing zones between Ca-type with Mg-type waters. Residence time of discharging waters in the ponds before mixing has an impact on fluid chemistry as it influences the equilibration time with the atmosphere. Acicular aragonite is the main textural type in hyper-alkaline Ca-type waters, acting as a substratum for the growth of calcite and brucite crystals. Low crystallinity, dumbbell shaped and double pyramid aragonite dominates in Mix-type water precipitates. Rate of supersaturation is essential for precipitation intensity and textural variation among the mineral assemblages in the different water types. Low S/ S˚ ratios in Mg-type and Ca-type waters (<1) reveal limited precipitation. Chemical reactions that lead to rapid mineral formation are enhanced in cases of Mix-type waters characterized by higher S/ S˚ ratios (>1.2). Detailed investigation of individual spring sites allowed the determination of geochemical and hydrological factors controlling the phases and textures of mineralogical assemblages in active, serpentinization-related, alkaline environments. Funding: We acknowledge funding from the People programme (Marie Curie Actions - ITN) of the European Union FP7 under REA Grant Agreement n˚ 608001.

Mixed methods in gerontological research: Do the qualitative and quantitative data “touch”?

PubMed Central

Happ, Mary Beth

2010-01-01

This paper distinguishes between parallel and integrated mixed methods research approaches. Barriers to integrated mixed methods approaches in gerontological research are discussed and critiqued. The author presents examples of mixed methods gerontological research to illustrate approaches to data integration at the levels of data analysis, interpretation, and research reporting. As a summary of the methodological literature, four basic levels of mixed methods data combination are proposed. Opportunities for mixing qualitative and quantitative data are explored using contemporary examples from published studies. Data transformation and visual display, judiciously applied, are proposed as pathways to fuller mixed methods data integration and analysis. Finally, practical strategies for mixing qualitative and quantitative data types are explicated as gerontological research moves beyond parallel mixed methods approaches to achieve data integration. PMID:20077973

A micromixer with consistent mixing performance for a wide range of flow rates.

PubMed

Goovaerts, Robert; Van Assche, Tom; Sonck, Marc; Denayer, Joeri; Desmet, Gert

2015-02-01

A micromixer with consistent mixing performance for a wide range of flow rates is presented. The mixer makes use of internally moving elements, i.e. steel balls that are located in dedicated mixing chambers. Movement is induced by a rotating magnetic field. To get better insight in differences between active and passive mixing, we studied a mixer that can operate in both regimes. A mixing performance study for a range of flow rates along with pressure drop data is presented. The response of the moving elements in regard to the magnetic field is shown experimentally and shows the limitations of earlier modeling studies. Lastly, the estimated power input on the fluids was calculated and allows for a comparison with more well-known convective-type mixers. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Clustering of samples and variables with mixed-type data

PubMed Central

Edelmann, Dominic; Kopp-Schneider, Annette

2017-01-01

Analysis of data measured on different scales is a relevant challenge. Biomedical studies often focus on high-throughput datasets of, e.g., quantitative measurements. However, the need for integration of other features possibly measured on different scales, e.g. clinical or cytogenetic factors, becomes increasingly important. The analysis results (e.g. a selection of relevant genes) are then visualized, while adding further information, like clinical factors, on top. However, a more integrative approach is desirable, where all available data are analyzed jointly, and where also in the visualization different data sources are combined in a more natural way. Here we specifically target integrative visualization and present a heatmap-style graphic display. To this end, we develop and explore methods for clustering mixed-type data, with special focus on clustering variables. Clustering of variables does not receive as much attention in the literature as does clustering of samples. We extend the variables clustering methodology by two new approaches, one based on the combination of different association measures and the other on distance correlation. With simulation studies we evaluate and compare different clustering strategies. Applying specific methods for mixed-type data proves to be comparable and in many cases beneficial as compared to standard approaches applied to corresponding quantitative or binarized data. Our two novel approaches for mixed-type variables show similar or better performance than the existing methods ClustOfVar and bias-corrected mutual information. Further, in contrast to ClustOfVar, our methods provide dissimilarity matrices, which is an advantage, especially for the purpose of visualization. Real data examples aim to give an impression of various kinds of potential applications for the integrative heatmap and other graphical displays based on dissimilarity matrices. We demonstrate that the presented integrative heatmap provides more information than common data displays about the relationship among variables and samples. The described clustering and visualization methods are implemented in our R package CluMix available from https://cran.r-project.org/web/packages/CluMix. PMID:29182671

Expansion of lymph node metastasis in mixed-type submucosal invasive gastric cancer.

PubMed

Mikami, Koji; Hirano, Yukiko; Futami, Kitaro; Maekawa, Takafumi

2017-07-18

Mixed-type early gastric cancer (differentiated and undifferentiated components) incurs a higher risk of lymph node metastasis than pure-type early gastric cancer (only differentiated or only undifferentiated components). Therefore, we investigated the expansion of lymph node metastasis in mixed-type submucosal invasive gastric cancer in order to establish the most appropriate treatment for mixed-type cancer. We retrospectively analyzed 279 consecutive patients with submucosal invasive gastric cancer who underwent curative gastrectomy for gastric cancer between 1996 and 2015. We classified the patients into the mixed-type and pure-type groups according to histologic examination and evaluated the expansion of lymph node metastasis. The rate of lymph node metastasis was 23.7% (66/279) in the total patients, 36.4% (36/99) in the mixed-type group, and 16.6% (30/180) in the pure-type group. The significant independent risk factors for lymph node metastasis were tumor size ≥2.0 cm (P = 0.014), mixed-type gastric cancer (P < 0.001), and lymphatic invasion (P < 0.001). Lymphatic invasion and lymph node metastasis had a strong relationship in mixed-type group. The rates of no. 7 lymph node metastasis in the total patients and mixed-type group were 2.9% (8/279) and 5.1% (5/99), respectively; the rates of no. 8a lymph node metastasis were 1.4% (4/279) and 4.0% (4/99), respectively. Mixed histological type is an independent risk factor for lymph node metastasis. Lymph node metastasis in mixed-type gastric cancer involves expansion to the no. 7 and no. 8a lymph nodes. Therefore, lymphadenectomy for mixed-type submucosal invasive gastric cancer requires D1+ or D2 dissection. Copyright © 2017. Published by Elsevier Taiwan.

Quality characterization of groundwater in Koilsagar project area, Mahabubnagar District, Andhra Pradesh, India

NASA Astrophysics Data System (ADS)

Raju, C. Sudarsana; Goud, P. V. Prakash

1990-09-01

Studies of groundwater chemistry in the Koilsagar project area of Andhra Pradesh indicate that the waters are sodium bicarbonate, sodium chloride, mixed cationic-mixed anionic, mixed cationic Na dominating bicarbonate, and mixed cationic Ca dominating bicarbonate types. Of them, sodium bicarbonate and mixed cationic Mg dominating bicarbonate types of waters are more prevalent. Isocone mapping of specific conductance indicates that the ionic concentration increases from east to west in the area. Graphical treatment of chemical data reveals that, in general, the area has basic water, whereas the left flank canal area is dominated by secondary alkaline water, and Pallamarri and Pedda Rajmur villages have strongly acidic waters. Ion-exchange studies show that cation-anion exchanges exist all over the area except for two places, which have a base exchange hardened type of water. Graphical representation further shows that most of the area has medium salinity-low sodium (C2S1) water useful for irrigation purposes. High salinity-low sodium (C3S1) and high salinity-medium sodium (C3S2) waters are present in some areas, which need adequate drainage to overcome the salinity problem.

Mixed pro and antisaccade performance in children and adults.

PubMed

Irving, Elizabeth L; Tajik-Parvinchi, Diana J; Lillakas, Linda; González, Esther G; Steinbach, Martin J

2009-02-19

Pro and antisaccades are usually presented in blocks of similar type but they can also be presented such that prosaccade and antisaccade eye movements are mixed and a cue, usually the shape/colour of the fixation target or the peripheral target, determines which type of eye movement is required in a particular trial. A mixed-saccade task theoretically equalizes the inhibitory requirements for pro and antisaccades. Using a mixed-saccade task paradigm the aims of the study were to: 1) compare pro and antisaccades of children, 2) compare performance of children and adults and 3) explore the effect of increased working memory load in adults. The eye movements of 22 children (5-12 years) and 22 adults (20-51 years) were examined using a video-based eye tracking system (El-Mar Series 2020 Eye Tracker, Toronto, Canada). The task was a mixed-saccade task of pro and antisaccades and the colour of the peripheral target was the cue for whether the required saccade was to be a pro or an antisaccade. The children performed the mixed-saccade task and 11 adults performed the same mixed-saccade task alone and in a dual-task paradigm (together with mental subtraction or number repetition). A second group of 11 adults performed the mixed-saccade task alone. Children made mainly antisaccade errors. The adults' error rates increased in the mental subtraction dual-task condition but both antisaccade and prosaccade errors were made. It was concluded that the increased error rates of these two groups are reflective of different processing dynamics.

Synchronization in counter-rotating oscillators.

PubMed

Bhowmick, Sourav K; Ghosh, Dibakar; Dana, Syamal K

2011-09-01

An oscillatory system can have opposite senses of rotation, clockwise or anticlockwise. We present a general mathematical description of how to obtain counter-rotating oscillators from the definition of a dynamical system. A type of mixed synchronization emerges in counter-rotating oscillators under diffusive scalar coupling when complete synchronization and antisynchronization coexist in different state variables. We present numerical examples of limit cycle van der Pol oscillator and chaotic Rössler and Lorenz systems. Stability conditions of mixed synchronization are analytically obtained for both Rössler and Lorenz systems. Experimental evidences of counter-rotating limit cycle and chaotic oscillators and mixed synchronization are given in electronic circuits.

Elastic properties and optical absorption studies of mixed alkali borogermanate glasses

NASA Astrophysics Data System (ADS)

Taqiullah, S. M.; Ahmmad, Shaik Kareem; Samee, M. A.; Rahman, Syed

2018-05-01

First time the mixed alkali effect (MAE) has been investigated in the glass system xNa2O-(30-x)Li2O-40B2O3- 30GeO2 (0≤x≤30 mol%) through density and optical absorption studies. The present glasses were prepared by melt quench technique. The density of the present glasses varies non-linearly exhibiting mixed alkali effect. Using the density data, the elastic moduli namely Young's modulus, bulk and shear modulus show strong linear dependence as a function of compositional parameter. From the absorption edge studies, the values of optical band gap energies for all transitions have been evaluated. It was established that the type of electronic transition in the present glass system is indirect allowed. The indirect optical band gap exhibit non-linear behavior with compositional parameter showing the mixed alkali effect.

Approximating a retarded-advanced differential equation that models human phonation

NASA Astrophysics Data System (ADS)

Teodoro, M. Filomena

2017-11-01

In [1, 2, 3] we have got the numerical solution of a linear mixed type functional differential equation (MTFDE) introduced initially in [4], considering the autonomous and non-autonomous case by collocation, least squares and finite element methods considering B-splines basis set. The present work introduces a numerical scheme using least squares method (LSM) and Gaussian basis functions to solve numerically a nonlinear mixed type equation with symmetric delay and advance which models human phonation. The preliminary results are promising. We obtain an accuracy comparable with the previous results.

Efficient topological chaos embedded in the blinking vortex system.

PubMed

Kin, Eiko; Sakajo, Takashi

2005-06-01

We consider the particle mixing in the plane by two vortex points appearing one after the other, called the blinking vortex system. Mathematical and numerical studies of the system reveal that the chaotic particle mixing, i.e., the chaotic advection, is observed due to the homoclinic chaos, but the mixing region is restricted locally in the neighborhood of the vortex points. The present article shows that it is possible to realize a global and efficient chaotic advection in the blinking vortex system with the help of the Thurston-Nielsen theory, which classifies periodic orbits for homeomorphisms in the plane into three types: periodic, reducible, and pseudo-Anosov (pA). It is mathematically shown that periodic orbits of pA type generate a complicated dynamics, which is called topological chaos. We show that the combination of the local chaotic mixing due to the topological chaos and the dipole-like return orbits realize an efficient and global particle mixing in the blinking vortex system.

Continuous spin fields of mixed-symmetry type

NASA Astrophysics Data System (ADS)

Alkalaev, Konstantin; Grigoriev, Maxim

2018-03-01

We propose a description of continuous spin massless fields of mixed-symmetry type in Minkowski space at the level of equations of motion. It is based on the appropriately modified version of the constrained system originally used to describe massless bosonic fields of mixed-symmetry type. The description is shown to produce generalized versions of triplet, metric-like, and light-cone formulations. In particular, for scalar continuous spin fields we reproduce the Bekaert-Mourad formulation and the Schuster-Toro formulation. Because a continuous spin system inevitably involves infinite number of fields, specification of the allowed class of field configurations becomes a part of its definition. We show that the naive choice leads to an empty system and propose a suitable class resulting in the correct degrees of freedom. We also demonstrate that the gauge symmetries present in the formulation are all Stueckelberg-like so that the continuous spin system is not a genuine gauge theory.

Stratification and salt-wedge in the Seomjin river estuary under the idealized tidal influence

NASA Astrophysics Data System (ADS)

Hwang, Jin Hwan; Jang, Dongmin; Kim, Yong Hoon

2017-12-01

Advection, straining, and vertical mixing play primary roles in the process of estuarine stratification. Estuaries can be classified as salt-wedge, partially-mixed or well-mixed depending on the vertical density structure determined by the balancing of advection, mixing and straining. In particular, straining plays a major role in the stratification of the estuarine water body along the estuarine channel. Also, the behavior of a salt wedge with a halocline shape in a stratified channel can be controlled by the competition between straining and mixing induced by buoyancy from the riverine source and tidal forcing. The present study uses Finite Volume Coastal Ocean Model (FVCOM) to show that straining and vertical mixing play major roles in controlling along-channel flow and stratification structures in the Seomjin river estuary (SRE) under idealized conditions. The Potential Energy Anomaly (PEA) dynamic equation quantifies the governing processes thereby enabling the determination of the stratification type. By comparing terms in the equation, we examined how the relative strengths of straining and mixing alter the stratification types in the SRE due to changes in river discharge and the depth resulting from dredging activities. SRE under idealized tidal forcing tends to be partially-mixed based on an analysis of the balance between terms and the vertical structure of salinity, and the morphological and hydrological change in SRE results in the shift of stratification type. While the depth affects the mixing, the freshwater discharge mainly controls the straining, and the balance between mixing and straining determines the final state of the stratification in an estuarine channel. As a result, the development and location of a salt wedge along the channel in a partially mixed and highly stratified condition is also determined by the ratio of straining to mixing. Finally, our findings confirm that the contributions of mixing and straining can be assessed by using the conventional non-dimensional parameters with respect to salt-wedge behavior.

Ampullary Mixed Adenoneuroendocrine Carcinoma: Surprise Histology, Familiar Management.

PubMed

Mahansaria, Shyam Sunder; Agrawal, Nikhil; Arora, Asit; Bihari, Chhagan; Appukuttan, Murali; Chattopadhyay, Tushar Kanti

2017-10-01

Mixed adenoneuroendocrine carcinoma (MANEC) has recently been defined by the World Health Organization in 2010. These are rare tumors and MANECs of ampullary region are even rarer. Only 19 cases have been reported in literature. We present 3 cases; the largest series, second case of amphicrine tumor and first case associated with chronic pancreatitis. Retrospective review of 3 patients who were diagnosed to have ampullary MANEC. All 3 patients were diagnosed preoperatively as neuroendocrine carcinoma and underwent margin negative pancreaticoduodenectomy. The histopathology revealed MANECs of small cell, mixed type in 2 patients and large cell, amphicrine type in 1 patient. The neuroendocrine component was grade 3 in all, the tumor was T3 in 2 and T2 in 1 and all had nodal metastases. Two patients received adjuvant chemotherapy and 2 of them had recurrence at 13 and 16 months. The median survival was 15 months. Ampullary MANECs are rare tumors. They are diagnosed on histopathologic examination of the resected specimen. Clinical presentation, management, and prognosis is similar to ampullary adenocarcinoma in literature.

Integrating Quantitative and Qualitative Results in Health Science Mixed Methods Research Through Joint Displays.

PubMed

Guetterman, Timothy C; Fetters, Michael D; Creswell, John W

2015-11-01

Mixed methods research is becoming an important methodology to investigate complex health-related topics, yet the meaningful integration of qualitative and quantitative data remains elusive and needs further development. A promising innovation to facilitate integration is the use of visual joint displays that bring data together visually to draw out new insights. The purpose of this study was to identify exemplar joint displays by analyzing the various types of joint displays being used in published articles. We searched for empirical articles that included joint displays in 3 journals that publish state-of-the-art mixed methods research. We analyzed each of 19 identified joint displays to extract the type of display, mixed methods design, purpose, rationale, qualitative and quantitative data sources, integration approaches, and analytic strategies. Our analysis focused on what each display communicated and its representation of mixed methods analysis. The most prevalent types of joint displays were statistics-by-themes and side-by-side comparisons. Innovative joint displays connected findings to theoretical frameworks or recommendations. Researchers used joint displays for convergent, explanatory sequential, exploratory sequential, and intervention designs. We identified exemplars for each of these designs by analyzing the inferences gained through using the joint display. Exemplars represented mixed methods integration, presented integrated results, and yielded new insights. Joint displays appear to provide a structure to discuss the integrated analysis and assist both researchers and readers in understanding how mixed methods provides new insights. We encourage researchers to use joint displays to integrate and represent mixed methods analysis and discuss their value. © 2015 Annals of Family Medicine, Inc.

Integrating Quantitative and Qualitative Results in Health Science Mixed Methods Research Through Joint Displays

PubMed Central

Guetterman, Timothy C.; Fetters, Michael D.; Creswell, John W.

2015-01-01

PURPOSE Mixed methods research is becoming an important methodology to investigate complex health-related topics, yet the meaningful integration of qualitative and quantitative data remains elusive and needs further development. A promising innovation to facilitate integration is the use of visual joint displays that bring data together visually to draw out new insights. The purpose of this study was to identify exemplar joint displays by analyzing the various types of joint displays being used in published articles. METHODS We searched for empirical articles that included joint displays in 3 journals that publish state-of-the-art mixed methods research. We analyzed each of 19 identified joint displays to extract the type of display, mixed methods design, purpose, rationale, qualitative and quantitative data sources, integration approaches, and analytic strategies. Our analysis focused on what each display communicated and its representation of mixed methods analysis. RESULTS The most prevalent types of joint displays were statistics-by-themes and side-by-side comparisons. Innovative joint displays connected findings to theoretical frameworks or recommendations. Researchers used joint displays for convergent, explanatory sequential, exploratory sequential, and intervention designs. We identified exemplars for each of these designs by analyzing the inferences gained through using the joint display. Exemplars represented mixed methods integration, presented integrated results, and yielded new insights. CONCLUSIONS Joint displays appear to provide a structure to discuss the integrated analysis and assist both researchers and readers in understanding how mixed methods provides new insights. We encourage researchers to use joint displays to integrate and represent mixed methods analysis and discuss their value. PMID:26553895

Low-temperature Ignition-delay Characteristics of Several Rocket Fuels with Mixed Acid in Modified Open-cup-type Apparatus

NASA Technical Reports Server (NTRS)

Miller, Riley O

1950-01-01

Summaries of low-temperature self-ignition data of various rocket fuels with mixed acid (nitric plus sulfuric) are presented. Several fuels are shown to have shorter ignition-delay intervals and less variation in delay intervals at moderate and sub-zero temperatures than crude N-ethylaniline (monoethylaniline),a rocket fuel in current use.

Chemical and physical characteristics of water in estuaries of Texas, October 1976-September 1978

USGS Publications Warehouse

Fisher, J.C.

1982-01-01

The coastal waters of Texas are not classical estuaries, but are similar to them in ecosystems and mixing phenomena. A description of various types of estuaries is presented in "Estuaries" edited by Lauff (1967, p. 3-11). The term estuary as used in this report, refers to concomitant water bodies in which streamflow mixes with seawater.

Theoretical study of mixing in liquid clouds – Part 1: Classical concepts

DOE PAGES

Korolev, Alexei; Khain, Alex; Pinsky, Mark; ...

2016-07-28

The present study considers final stages of in-cloud mixing in the framework of classical concept of homogeneous and extreme inhomogeneous mixing. Simple analytical relationships between basic microphysical parameters were obtained for homogeneous and extreme inhomogeneous mixing based on the adiabatic consideration. It was demonstrated that during homogeneous mixing the functional relationships between the moments of the droplets size distribution hold only during the primary stage of mixing. Subsequent random mixing between already mixed parcels and undiluted cloud parcels breaks these relationships. However, during extreme inhomogeneous mixing the functional relationships between the microphysical parameters hold both for primary and subsequent mixing.more » The obtained relationships can be used to identify the type of mixing from in situ observations. The effectiveness of the developed method was demonstrated using in situ data collected in convective clouds. It was found that for the specific set of in situ measurements the interaction between cloudy and entrained environments was dominated by extreme inhomogeneous mixing.« less

THz QCL self-mixing interferometry for biomedical applications

NASA Astrophysics Data System (ADS)

Rakić, Aleksandar D.; Taimre, Thomas; Bertling, Karl; Lim, Yah Leng; Wilson, Stephen J.; Nikolić, Milan; Valavanis, Alexander; Indjin, Dragan; Linfield, Edmund H.; Davies, A. Giles; Ferguson, Blake; Walker, Graeme; Schaider, Helmut; Soyer, H. Peter

2014-09-01

In this paper, we introduce the self-mixing phenomenon in terahertz quantum cascade lasers (THz QCLs) and present recent advancements in the development of coherent THz imaging and sensing systems that exploit the self-mixing effect. We describe an imaging method which utilises the interferometric nature of optical feedback in a THz QCL to employ it as a homodyning transceiver. This results in a highly sensitive and compact scheme. Due to the inherently low penetration depth of THz radiation in hydrated biological tissue, imaging of superficial skin is an ideal application for this technique. We present results for imaging of excised skin tissue, showing high-contrast between different tissue types and pathologies.

Metformin and Its Sulfenamide Prodrugs Inhibit Human Cholinesterase Activity.

PubMed

Markowicz-Piasecka, Magdalena; Sikora, Joanna; Mateusiak, Łukasz; Mikiciuk-Olasik, Elżbieta; Huttunen, Kristiina M

2017-01-01

The results of epidemiological and pathophysiological studies suggest that type 2 diabetes mellitus (T2DM) may predispose to Alzheimer's disease (AD). The two conditions present similar glucose levels, insulin resistance, and biochemical etiologies such as inflammation and oxidative stress. The diabetic state also contributes to increased acetylcholinesterase (AChE) activity, which is one of the factors leading to neurodegeneration in AD. The aim of this study was to assess in vitro the effects of metformin, phenformin, and metformin sulfenamide prodrugs on the activity of human AChE and butyrylcholinesterase (BuChE) and establish the type of inhibition. Metformin inhibited 50% of the AChE activity at micromolar concentrations (2.35  μ mol/mL, mixed type of inhibition) and seemed to be selective towards AChE since it presented low anti-BuChE activity. The tested metformin prodrugs inhibited cholinesterases (ChE) at nanomolar range and thus were more active than metformin or phenformin. The cyclohexyl sulfenamide prodrug demonstrated the highest activity towards both AChE (IC 50  = 890 nmol/mL, noncompetitive inhibition) and BuChE (IC 50  = 28 nmol/mL, mixed type inhibition), while the octyl sulfenamide prodrug did not present anti-AChE activity, but exhibited mixed inhibition towards BuChE (IC 50  = 184 nmol/mL). Therefore, these two bulkier prodrugs were concluded to be the most selective compounds for BuChE over AChE. In conclusion, it was demonstrated that biguanides present a novel class of inhibitors for AChE and BuChE and encourages further studies of these compounds for developing both selective and nonselective inhibitors of ChEs in the future.

Large field inflation from axion mixing

NASA Astrophysics Data System (ADS)

Shiu, Gary; Staessens, Wieland; Ye, Fang

2015-06-01

We study the general multi-axion systems, focusing on the possibility of large field inflation driven by axions. We find that through axion mixing from a non-diagonal metric on the moduli space and/or from Stückelberg coupling to a U(1) gauge field, an effectively super-Planckian decay constant can be generated without the need of "alignment" in the axion decay constants. We also investigate the consistency conditions related to the gauge symmetries in the multi-axion systems, such as vanishing gauge anomalies and the potential presence of generalized Chern-Simons terms. Our scenario applies generally to field theory models whose axion periodicities are intrinsically sub-Planckian, but it is most naturally realized in string theory. The types of axion mixings invoked in our scenario appear quite commonly in D-brane models, and we present its implementation in type II superstring theory. Explicit stringy models exhibiting all the characteristics of our ideas are constructed within the frameworks of Type IIA intersecting D6-brane models on and Type IIB intersecting D7-brane models on Swiss-Cheese Calabi-Yau orientifolds.

Scale-up on basis of structured mixing models: A new concept.

PubMed

Mayr, B; Moser, A; Nagy, E; Horvat, P

1994-02-05

A new scale-up concept based upon mixing models for bioreactors equipped with Rushton turbines using the tanks-in-series concept is presented. The physical mixing model includes four adjustable parameters, i.e., radial and axial circulation time, number of ideally mixed elements in one cascade, and the volume of the ideally mixed turbine region. The values of the model parameters were adjusted with the application of a modified Monte-Carlo optimization method, which fitted the simulated response function to the experimental curve. The number of cascade elements turned out to be constant (N = 4). The model parameter radial circulation time is in good agreement with the one obtained by the pumping capacity. In case of remaining parameters a first or second order formal equation was developed, including four operational parameters (stirring and aeration intensity, scale, viscosity). This concept can be extended to several other types of bioreactors as well, and it seems to be a suitable tool to compare the bioprocess performance of different types of bioreactors. (c) 1994 John Wiley & Sons, Inc.

TDP-43 stage, mixed pathologies, and clinical Alzheimer’s-type dementia

PubMed Central

James, Bryan D.; Wilson, Robert S.; Boyle, Patricia A.; Trojanowski, John Q.; Bennett, David A.; Schneider, Julie A.

2016-01-01

Hyperphosphorylated transactive response DNA-binding protein 43 (TDP-43, encoded by TARDBP) proteinopathy has recently been described in ageing and in association with cognitive impairment, especially in the context of Alzheimer’s disease pathology. To explore the role of mixed Alzheimer’s disease and TDP-43 pathologies in clinical Alzheimer’s-type dementia, we performed a comprehensive investigation of TDP-43, mixed pathologies, and clinical Alzheimer’s-type dementia in a large cohort of community-dwelling older subjects. We tested the hypotheses that TDP-43 with Alzheimer’s disease pathology is a common mixed pathology; is related to increased likelihood of expressing clinical Alzheimer’s-type dementia; and that TDP-43 pathologic stage is an important determinant of clinical Alzheimer’s-type dementia. Data came from 946 older adults with (n = 398) and without dementia (n = 548) from the Rush Memory and Aging Project and Religious Orders Study. TDP-43 proteinopathy (cytoplasmic inclusions) was present in 496 (52%) subjects, and the pattern of deposition was classified as stage 0 (none; 48%), stage 1 (amygdala; 18%), stage 2 (extension to hippocampus/entorhinal; 21%), or stage 3 (extension to neocortex; 14%). TDP-43 pathology combined with a pathologic diagnosis of Alzheimer’s disease was a common mixed pathology (37% of all participants), and the proportion of subjects with clinical Alzheimer’s-type dementia formerly labelled ‘pure pathologic diagnosis of Alzheimer’s disease’ was halved when TDP-43 was considered. In logistic regression models adjusted for age, sex, and education, TDP-43 pathology was associated with clinical Alzheimer’s-type dementia (odds ratio = 1.51, 95% confidence interval = 1.11, 2.05) independent of pathological Alzheimer’s disease (odds ratio = 4.30, 95% confidence interval = 3.08, 6.01) or other pathologies (infarcts, arteriolosclerosis, Lewy bodies, and hippocampal sclerosis). Mixed Alzheimer’s disease and TDP-43 pathologies were associated with higher odds of clinical Alzheimer’s-type dementia (odds ratio = 6.73, 95% confidence interval = 4.18, 10.85) than pathologic Alzheimer’s disease alone (odds ratio = 4.62, 95% confidence interval = 2.84, 7.52). In models examining TDP-43 stage, a dose-response relationship with clinical Alzheimer’s-type dementia was observed, and a significant association was observed starting at stage 2, extension beyond the amygdala. In this large sample from almost 1000 community participants, we observed that TDP-43 proteinopathy was very common, frequently mixed with pathological Alzheimer’s disease, and associated with a higher likelihood of the clinical expression of clinical Alzheimer’s-type dementia but only when extended beyond the amygdala. PMID:27694152

75 FR 22707 - United States Standards for Grades of Potatoes

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

... characteristic requirement to allow mixed colors and/or types of potatoes when designated as a mixed or specialty... inserting language into the standard to allow mixed colors and/or types of potatoes when designated as a... proposed standard to allow for mixed colors and/or types of potatoes when designated as a mixed or...

Expediency of wet-mix shotcreting in mines of Vostoktsvetmet

NASA Astrophysics Data System (ADS)

Shaposhnik, YuN

2018-03-01

This paper offers a substantiation of the transition from heavy and difficult-to-install steel frame support to the cheaper and simpler reinforced shotcrete lining (at the same bearing-capacity of the support). The process line for the preparation of the shotcrete mix is designed. The author of the paper presents calculation of the material inputs and labor costs of installation of different support types in Kazakhstan Mines. The economic efficiency of the wet-mix shotcrete spraying technology is illustrated in terms of Orlov and Artemevsk Mines.

Turbulent mixing and beyond: non-equilibrium processes from atomistic to astrophysical scales II

PubMed Central

Abarzhi, S. I.; Gauthier, S.; Sreenivasan, K. R.

2013-01-01

This Introduction summarizes and provides a perspective on the papers representing one of the key themes of the ‘Turbulent mixing and beyond’ programme—the hydrodynamic instabilities of the Rayleigh–Taylor (RT) and Richtmyer–Meshkov (RM) type and their applications in nature and technology. The collection is intended to present the reader a balanced overview of the theoretical, experimental and numerical studies of the subject and to assess what is firm in our knowledge of the RT and RM turbulent mixing. PMID:24146016

A mixed shear flexible finite element for the analysis of laminated plates

NASA Technical Reports Server (NTRS)

Putcha, N. S.; Reddy, J. N.

1984-01-01

A mixed shear flexible finite element based on the Hencky-Mindlin type shear deformation theory of laminated plates is presented and their behavior in bending is investigated. The element consists of three displacements, two rotations, and three moments as the generalized degrees of freedom per node. The numerical convergence and accuracy characteristics of the element are investigated by comparing the finite element solutions with the exact solutions. The present study shows that reduced-order integration of the stiffness coefficients due to shear is necessary to obtain accurate results for thin plates.

Stability of Mixed Preparations Consisting of Commercial Moisturizing Creams with an Ointment Base Investigated by Magnetic Resonance Imaging.

PubMed

Onuki, Yoshinori; Funatani, Chiaki; Yamamoto, Yoshihisa; Fukami, Toshiro; Koide, Tatsuo; Hayashi, Yoshihiro; Takayama, Kozo

2017-01-01

A moisturizing cream mixed with a steroid ointment is frequently prescribed to patients suffering from atopic dermatitis. However, there is a concern that the mixing operation causes destabilization. The present study was performed to investigate the stability of such preparations closely using magnetic resonance imaging (MRI). As sample preparations, five commercial moisturizing creams that are popular in Japan were mixed with an ointment base, a white petrolatum, at a volume ratio of 1 : 1. The mixed preparations were stored at 60°C to accelerate the destabilization processes. Subsequently, the phase separations induced by the storage test were monitored using MRI. Using advanced MR technologies including spin-spin relaxation time (T 2 ) mapping and MR spectroscopy, we successfully characterized the phase-separation behavior of the test samples. For most samples, phase separations developed by the bleeding of liquid oil components. From a sample consisting of an oil-in-water-type cream, Urepearl Cream 10%, a distinct phase-separation mode was observed, which was initiated by the aqueous component separating from the bottom part of the sample. The resultant phase separation was the most distinct among the test samples. To investigate the phase separation quantitatively and objectively, we conducted a histogram analysis on the acquired T 2 maps. The water-in-oil type creams were found to be much more stable after mixing with ointment base than those of oil-in-water type creams. This finding strongly supported the validity of the mixing operation traditionally conducted in pharmacies.

The effects of model composition design choices on high-fidelity simulations of motoneuron recruitment and firing behaviors

NASA Astrophysics Data System (ADS)

Allen, John M.; Elbasiouny, Sherif M.

2018-06-01

Objective. Computational models often require tradeoffs, such as balancing detail with efficiency; yet optimal balance should incorporate sound design features that do not bias the results of the specific scientific question under investigation. The present study examines how model design choices impact simulation results. Approach. We developed a rigorously-validated high-fidelity computational model of the spinal motoneuron pool to study three long-standing model design practices which have yet to be examined for their impact on motoneuron recruitment, firing rate, and force simulations. The practices examined were the use of: (1) generic cell models to simulate different motoneuron types, (2) discrete property ranges for different motoneuron types, and (3) biological homogeneity of cell properties within motoneuron types. Main results. Our results show that each of these practices accentuates conditions of motoneuron recruitment based on the size principle, and minimizes conditions of mixed and reversed recruitment orders, which have been observed in animal and human recordings. Specifically, strict motoneuron orderly size recruitment occurs, but in a compressed range, after which mixed and reverse motoneuron recruitment occurs due to the overlap in electrical properties of different motoneuron types. Additionally, these practices underestimate the motoneuron firing rates and force data simulated by existing models. Significance. Our results indicate that current modeling practices increase conditions of motoneuron recruitment based on the size principle, and decrease conditions of mixed and reversed recruitment order, which, in turn, impacts the predictions made by existing models on motoneuron recruitment, firing rate, and force. Additionally, mixed and reverse motoneuron recruitment generated higher muscle force than orderly size motoneuron recruitment in these simulations and represents one potential scheme to increase muscle efficiency. The examined model design practices, as well as the present results, are applicable to neuronal modeling throughout the nervous system.

The effects of model composition design choices on high-fidelity simulations of motoneuron recruitment and firing behaviors.

PubMed

Allen, John M; Elbasiouny, Sherif M

2018-06-01

Computational models often require tradeoffs, such as balancing detail with efficiency; yet optimal balance should incorporate sound design features that do not bias the results of the specific scientific question under investigation. The present study examines how model design choices impact simulation results. We developed a rigorously-validated high-fidelity computational model of the spinal motoneuron pool to study three long-standing model design practices which have yet to be examined for their impact on motoneuron recruitment, firing rate, and force simulations. The practices examined were the use of: (1) generic cell models to simulate different motoneuron types, (2) discrete property ranges for different motoneuron types, and (3) biological homogeneity of cell properties within motoneuron types. Our results show that each of these practices accentuates conditions of motoneuron recruitment based on the size principle, and minimizes conditions of mixed and reversed recruitment orders, which have been observed in animal and human recordings. Specifically, strict motoneuron orderly size recruitment occurs, but in a compressed range, after which mixed and reverse motoneuron recruitment occurs due to the overlap in electrical properties of different motoneuron types. Additionally, these practices underestimate the motoneuron firing rates and force data simulated by existing models. Our results indicate that current modeling practices increase conditions of motoneuron recruitment based on the size principle, and decrease conditions of mixed and reversed recruitment order, which, in turn, impacts the predictions made by existing models on motoneuron recruitment, firing rate, and force. Additionally, mixed and reverse motoneuron recruitment generated higher muscle force than orderly size motoneuron recruitment in these simulations and represents one potential scheme to increase muscle efficiency. The examined model design practices, as well as the present results, are applicable to neuronal modeling throughout the nervous system.

Reuse of thermosetting plastic waste for lightweight concrete.

PubMed

Panyakapo, Phaiboon; Panyakapo, Mallika

2008-01-01

This paper presents the utilization of thermosetting plastic as an admixture in the mix proportion of lightweight concrete. Since this type of plastic cannot be melted in the recycling process, its waste is expected to be more valuable by using as an admixture for the production of non-structural lightweight concrete. Experimental tests for the variation of mix proportion were carried out to determine the suitable proportion to achieve the required properties of lightweight concrete, which are: low dry density and acceptable compressive strength. The mix design in this research is the proportion of plastic, sand, water-cement ratio, aluminum powder, and lignite fly ash. The experimental results show that the plastic not only leads to a low dry density concrete, but also a low strength. It was found that the ratio of cement, sand, fly ash, and plastic equal to 1.0:0.8:0.3:0.9 is an appropriate mix proportion. The results of compressive strength and dry density are 4.14N/mm2 and 1395 kg/m3, respectively. This type of concrete meets most of the requirements for non-load-bearing lightweight concrete according to ASTM C129 Type II standard.

Prediction of periodic basal area increment for young-growth mixed conifers in sierra Nevada

Treesearch

Leroy K. Dolph

1988-01-01

Mixed-conifer forests are the largest vegetation type in California, covering more than 13 million acres (Barbour and Major 1977). This type, the Sierra Nevada Mixed Conifer (Society of American Foresters Forest cover type 243, Tappeiner 1980) dominates mid-elevations of the Sierra Nevada's western slopes. The extent of the mixed-conifer type and the amount of...

Relationships between perceived chewing ability, objective masticatory function and oral health-related quality of life in mandibulectomy or glossectomy patients with a dento-maxillary prosthesis.

PubMed

Aimaijiang, Yiliyaer; Otomaru, Takafumi; Taniguchi, Hisashi

2016-04-01

This preliminary study examined whether the type of surgery performed for head and neck lesion was associated perceived chewing ability, objective masticatory function, and oral health-related quality of life (OHRQoL) in patients who required a dento-maxillary prosthesis postoperatively. Thirty-eight patients with a dento-maxillary prosthesis were divided into three groups according to the type of surgery received: marginal mandibulectomy, segmental mandibulectomy with bony reconstruction, or glossectomy. Perceived chewing ability, objective mixing ability, and OHRQoL were evaluated using a food intake questionnaire, color-changeable chewing gum, and the Geriatric Oral Health Assessment Index (GOHAI), respectively. Differences in the scores obtained by the three measures were compared between the surgical groups using the Kruskal-Wallis test, and associations between the scores in each group were analyzed by Spearman's rank correlation analysis. Objective mixing ability was found to be significantly low only in patients who underwent glossectomy. No other measures differed significantly between the surgical groups. Perceived chewing ability and objective mixing ability were significantly associated in the marginal mandibulectomy and glossectomy groups but not in the segmental mandibulectomy group. Furthermore, GOHAI score was significantly associated with perceived chewing ability and objective mixing ability in the marginal mandibulectomy group. Within the limitations of this study, the present findings suggest that the type of surgery received might influence food mixing ability. Associations among food mixing ability, perceived chewing and OHRQoL are not accountable depending on the type of surgery received, indicating the presence of other contributing factors to be considered. Copyright © 2015 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

Subseafloor fluid mixing and fossilized microbial life in a Cretaceous 'Lost City'-type hydrothermal system at the Iberian Margin

NASA Astrophysics Data System (ADS)

Klein, F.; Humphris, S. E.; Guo, W.; Schubotz, F.; Schwarzenbach, E. M.; Orsi, W.

2015-12-01

Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support autotrophic microorganisms in the hydrated oceanic mantle (serpentinite). Despite the potentially significant implications for the distribution of microbial life on Earth and other water-bearing planetary bodies, our understanding of such environments remains elusive. In the present study we examined fossilized microbial communities and fluid mixing processes in the subseafloor of a Cretaceous 'Lost City'-type hydrothermal system at the passive Iberia Margin (ODP Leg 149, Hole 897D). Brucite and calcite co-precipitated from mixed fluids ca. 65m below the Cretaceous palaeo-seafloor at temperatures of 32±4°C within steep chemical gradients (fO2, pH, CH4, SO4, ΣCO2, etc) between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity within the oceanic basement. Dense microbial colonies are fossilized in brucite-calcite veins that are strongly enriched in organic carbon but depleted in 13C. We detected a combination of bacterial diether lipid biomarkers, archaeol and archaeal tetraethers analogous to those found in brucite-carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin during the Cretaceous, possibly before the onset of seafloor spreading in the Atlantic. 'Lost City'-type serpentinization systems have been discovered at mid-ocean ridges, in forearc settings of subduction zones and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments as demonstrated in the present study. Because equivalent systems have likely existed throughout most of Earth's history, fluid mixing may have provided the substrates and energy to support a unique subseafloor community of microorganisms over geological timescales.

Subseafloor fluid mixing and fossilized microbial life in a Cretaceous 'Lost City'-type hydrothermal system at the Iberian Margin

NASA Astrophysics Data System (ADS)

Klein, F.; Humphris, S. E.; Guo, W.; Schubotz, F.; Schwarzenbach, E. M.; Orsi, W.

2014-12-01

Subseafloor mixing of reduced hydrothermal fluids with seawater is believed to provide the energy and substrates needed to support autotrophic microorganisms in the hydrated oceanic mantle (serpentinite). Despite the potentially significant implications for the distribution of microbial life on Earth and other water-bearing planetary bodies, our understanding of such environments remains elusive. In the present study we examined fossilized microbial communities and fluid mixing processes in the subseafloor of a Cretaceous 'Lost City'-type hydrothermal system at the passive Iberia Margin (ODP Leg 149, Hole 897D). Brucite and calcite co-precipitated from mixed fluids ca. 65m below the Cretaceous palaeo-seafloor at temperatures of 32±4°C within steep chemical gradients (fO2, pH, CH4, SO4, ΣCO2, etc) between weathered, carbonate-rich serpentinite breccia and serpentinite. Mixing of oxidized seawater and strongly reducing hydrothermal fluid at moderate temperatures created conditions capable of supporting microbial activity within the oceanic basement. Dense microbial colonies are fossilized in brucite-calcite veins that are strongly enriched in organic carbon but depleted in 13C. We detected a combination of bacterial diether lipid biomarkers, archaeol and archaeal tetraethers analogous to those found in brucite-carbonate chimneys at the active Lost City hydrothermal field. The exposure of mantle rocks to seawater during the breakup of Pangaea fueled chemolithoautotrophic microbial communities at the Iberia Margin during the Cretaceous, possibly before the onset of seafloor spreading in the Atlantic. 'Lost City'-type serpentinization systems have been discovered at mid-ocean ridges, in forearc settings of subduction zones and at continental margins. It appears that, wherever they occur, they can support microbial life, even in deep subseafloor environments as demonstrated in the present study. Because equivalent systems have likely existed throughout most of Earth's history, fluid mixing may have provided the substrates and energy to support a unique subseafloor community of microorganisms over geological timescales.

Light emission mechanism of mixed host organic light-emitting diodes

NASA Astrophysics Data System (ADS)

Song, Wook; Lee, Jun Yeob

2015-03-01

Light emission mechanism of organic light-emitting diodes with a mixed host emitting layer was studied using an exciplex type mixed host and an exciplex free mixed host. Monitoring of the current density and luminance of the two type mixed host devices revealed that the light emission process of the exciplex type mixed host was dominated by energy transfer, while the light emission of the exciplex free mixed host was controlled by charge trapping. Mixed host composition was also critical to the light emission mechanism, and the contribution of the energy transfer process was maximized at 50:50 mixed host composition. Therefore, it was possible to manage the light emission process of the mixed host devices by managing the mixed host composition.

TREM-1 expression in craniopharyngioma and Rathke's cleft cyst: its possible implication for controversial pathology.

PubMed

Liu, Yi; Wang, Chao-Hu; Li, Dan-Ling; Zhang, Shi-Chao; Peng, Yu-Ping; Peng, Jun-Xiang; Song, Ye; Qi, Song-Tao; Pan, Jun

2016-08-02

Whether a mixed type of craniopharyngioma (CP) exists and whether papillary craniopharyngioma (pCP) is on a histopathological continuum with Rathke's cleft cyst (RCC) remain controversial. Herein, we examined the expression and localization of β-catenin, BRAF p.V600E (V600E), and triggering receptor expressed on myeloid cells-1 (TREM-1) in 58 samples including 20 pCPs, 26 adamantinomatous craniopharyngiomas (aCP), and 12 RCCs. Five aCPs were diagnosed with mixed type CPs and the remaining 21 cases were pure aCPs. Four of the 12 RCCs presented with significant squamous epithelium (SE). V600E immunoreactivity was observed in all pCPs in the cytoplasm, but not in the nuclei. aCPs and RCCs, including mixed type CP, did not express V600E. Nuclear β-catenin translocation was detected exclusively in aCPs. TREM-1 was expressed in pCPs. Additionally, TREM-1 expression was detected in the SE of 5 "mixed type" CPs, while it was absent in pure aCPs. TREM-1 was expressed in 4 RCCs with SE, but not in the remaining 8 RCCs. TREM-1 mRNA levels were compared in cultured pCP and aCP cells. TREM-1 mRNA level was significantly (p < 0.001; up to 4.045 fold) higher in pCPs than in aCPs. Western blotting revealed a significantly (p < 0.001; up to 7.19 fold) lower level of TREM-1 expression in aCP cells compared to that in pCP cells. Our findings further supported that RCC and pCP may represent two ends of a morphological spectrum. A variant showing overlapping histological features of aCP and pCP should not be considered as a mixed type.

Overflow Simulations using MPAS-Ocean in Idealized and Realistic Domains

NASA Astrophysics Data System (ADS)

Reckinger, S.; Petersen, M. R.; Reckinger, S. J.

2016-02-01

MPAS-Ocean is used to simulate an idealized, density-driven overflow using the dynamics of overflow mixing and entrainment (DOME) setup. Numerical simulations are benchmarked against other models, including the MITgcm's z-coordinate model and HIM's isopycnal coordinate model. A full parameter study is presented that looks at how sensitive overflow simulations are to vertical grid type, resolution, and viscosity. Horizontal resolutions with 50 km grid cells are under-resolved and produce poor results, regardless of other parameter settings. Vertical grids ranging in thickness from 15 m to 120 m were tested. A horizontal resolution of 10 km and a vertical resolution of 60 m are sufficient to resolve the mesoscale dynamics of the DOME configuration, which mimics real-world overflow parameters. Mixing and final buoyancy are least sensitive to horizontal viscosity, but strongly sensitive to vertical viscosity. This suggests that vertical viscosity could be adjusted in overflow water formation regions to influence mixing and product water characteristics. Also, the study shows that sigma coordinates produce much less mixing than z-type coordinates, resulting in heavier plumes that go further down slope. Sigma coordinates are less sensitive to changes in resolution but as sensitive to vertical viscosity compared to z-coordinates. Additionally, preliminary measurements of overflow diagnostics on global simulations using a realistic oceanic domain are presented.

Multi-font printed Mongolian document recognition system

NASA Astrophysics Data System (ADS)

Peng, Liangrui; Liu, Changsong; Ding, Xiaoqing; Wang, Hua; Jin, Jianming

2009-01-01

Mongolian is one of the major ethnic languages in China. Large amount of Mongolian printed documents need to be digitized in digital library and various applications. Traditional Mongolian script has unique writing style and multi-font-type variations, which bring challenges to Mongolian OCR research. As traditional Mongolian script has some characteristics, for example, one character may be part of another character, we define the character set for recognition according to the segmented components, and the components are combined into characters by rule-based post-processing module. For character recognition, a method based on visual directional feature and multi-level classifiers is presented. For character segmentation, a scheme is used to find the segmentation point by analyzing the properties of projection and connected components. As Mongolian has different font-types which are categorized into two major groups, the parameter of segmentation is adjusted for each group. A font-type classification method for the two font-type group is introduced. For recognition of Mongolian text mixed with Chinese and English, language identification and relevant character recognition kernels are integrated. Experiments show that the presented methods are effective. The text recognition rate is 96.9% on the test samples from practical documents with multi-font-types and mixed scripts.

Deficiency of the autologous mixed lymphocyte reactions of non-T/T and T/T type in intravenous drug abusers infected by the human immunodeficiency virus (HIV).

PubMed

Puppo, F; Pierri, I; Rogna, S; Pattarini, R; Piovano, P L; Catellani, S; Varnier, O E; Indiveri, F

1987-01-01

In the present study both responsiveness and stimulatory capacity in autologous mixed lymphocyte reactions (AMLRs) of non-T/T and T/T type, as well as in allogeneic mixed lymphocyte reaction (MLR), were evaluated in 30 intravenous drug abusers (IDAs) infected by the human immunodeficiency virus (HIV) and in 10 HIV-negative IDAs. The production of interleukin 2 (IL2), and the expression of HLA Class II antigens and IL2 receptors by PHA-activated T lymphocytes were also evaluated. A severe impairment of both responsiveness and stimulatory capacity in MLR and AMLRs was found in the HIV-positive IDAs and not in the HIV-negative IDAs. The HIV-positive IDAs showed also a defective expression of HLA Class II antigens, whereas the IL2 production and the IL2 receptor expression were in the normal range. The present data are consistent with similar observations in male homosexuals with AIDS-related complex and confirm that the HIV infection induces a broad spectrum of immunological abnormalities leading to a progressive derangement of the immunocompetence.

Numerical methods for systems of conservation laws of mixed type using flux splitting

NASA Technical Reports Server (NTRS)

Shu, Chi-Wang

1990-01-01

The essentially non-oscillatory (ENO) finite difference scheme is applied to systems of conservation laws of mixed hyperbolic-elliptic type. A flux splitting, with the corresponding Jacobi matrices having real and positive/negative eigenvalues, is used. The hyperbolic ENO operator is applied separately. The scheme is numerically tested on the van der Waals equation in fluid dynamics. Convergence was observed with good resolution to weak solutions for various Riemann problems, which are then numerically checked to be admissible as the viscosity-capillarity limits. The interesting phenomena of the shrinking of elliptic regions if they are present in the initial conditions were also observed.

Characterization of manganese?gallium mixed oxide powders

NASA Astrophysics Data System (ADS)

Sánchez Escribano, Vicente; Fernández López, Enrique; Sánchez Huidobro, Paula; Panizza, Marta; Resini, Carlo; Gallardo-Amores, José M.; Busca, Guido

2003-11-01

MnGa mixed oxides have been prepared by coprecipitation of the corresponding oxo-hydroxides as powders and have been characterized in relation to their structural and optical properties. The materials have been characterized by XRD, TG-DTA, skeletal IR and UV-visible-NIR spectroscopies. Large solubility of Mn in the diaspore type α-GaOOH oxo-hydroxide has been found. The spinel related structures of hausmannite Mn 3O 4 and of β-gallia present large reciprocal solubilities at least in a metastable form. At high temperature also bixbyite-type α-Mn 2O 3 solid solutions containing up to 20% at. Ga have been observed.

Perforator chimerism for the reconstruction of complex defects: A new chimeric free flap classification system.

PubMed

Kim, Jeong Tae; Kim, Youn Hwan; Ghanem, Ali M

2015-11-01

Complex defects present structural and functional challenges to reconstructive surgeons. When compared to multiple free flaps or staged reconstruction, the use of chimeric flaps to reconstruct such defects have many advantages such as reduced number of operative procedures and donor site morbidity as well as preservation of recipient vessels. With increased popularity of perforator flaps, chimeric flaps' harvest and design has benefited from 'perforator concept' towards more versatile and better reconstruction solutions. This article discusses perforator based chimeric flaps and presents a practice based classification system that incorporates the perforator flap concept into "Perforator Chimerism". The authors analyzed a variety of chimeric patterns used in 31 consecutive cases to present illustrative case series and their new classification system. Accordingly, chimeric flaps are classified into four types. Type I: Classical Chimerism, Type II: Anastomotic Chimerism, Type III: Perforator Chimerism and Type IV Mixed Chimerism. Types I on specific source vessel anatomy whilst Type II requires microvascular anastomosis to create the chimeric reconstructive solution. Type III chimeric flaps utilizes the perforator concept to raise two components of tissues without microvascular anastomosis between them. Type IV chimeric flaps are mixed type flaps comprising any combination of Types I to III. Incorporation of the perforator concept in planning and designing chimeric flaps has allowed safe, effective and aesthetically superior reconstruction of complex defects. The new classification system aids reconstructive surgeons and trainees to understand chimeric flaps design, facilitating effective incorporation of this important reconstructive technique into the armamentarium of the reconstruction toolbox. Copyright © 2015 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

The Apollo 16 regolith - A petrographically-constrained chemical mixing model

NASA Technical Reports Server (NTRS)

Kempa, M. J.; Papike, J. J.; White, C.

1980-01-01

A mixing model for Apollo 16 regolith samples has been developed, which differs from other A-16 mixing models in that it is both petrographically constrained and statistically sound. The model was developed using three components representative of rock types present at the A-16 site, plus a representative mare basalt. A linear least-squares fitting program employing the chi-squared test and sum of components was used to determine goodness of fit. Results for surface soils indicate that either there are no significant differences between Cayley and Descartes material at the A-16 site or, if differences do exist, they have been obscured by meteoritic reworking and mixing of the lithologies.

Comparing the effects of negative and mixed emotional messages on predicted occasional excessive drinking.

PubMed

Carrera, Pilar; Caballero, Amparo; Muñoz, Dolores

2008-01-01

In this work we present two types of emotional message, negative (sadness) versus mixed (joy and sadness), with the aim of studying their differential effect on attitude change and the probability estimated by participants of repeating the behavior of occasional excessive drinking in the near future. The results show that for the group of participants with moderate experience in this behavior the negative message, compared to the mixed one, is associated with higher probability of repeating the risk behavior and a less negative attitude toward it. These results suggest that mixed emotional messages (e.g. joy and sadness messages) could be more effective in campaigns for the prevention of this risk behavior.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Andronov, V.A.; Zhidov, I.G.; Meskov, E.E.

This report describes an extensive program of investigations conducted at Arzamas-16 in Russia over the past several decades. The focus of the work is on material interface instability and the mixing of two materials. Part 1 of the report discusses analytical and computational studies of hydrodynamic instabilities and turbulent mixing. The EGAK codes are described and results are illustrated for several types of unstable flow. Semiempirical turbulence transport equations are derived for the mixing of two materials, and their capabilities are illustrated for several examples. Part 2 discusses the experimental studies that have been performed to investigate instabilities and turbulentmore » mixing. Shock-tube and jelly techniques are described in considerable detail. Results are presented for many circumstances and configurations.« less

Technical advisory guide (TAG) for microsurfacing pilot projects.

DOT National Transportation Integrated Search

2003-10-01

This document provides an overview of the types of microsurfacing presently used in California, including information on materials and specifications, mix design, project selection, details regarding construction, and a troubleshooting guide to assis...

Properties of ambient cured blended alkali activated cement concrete

NASA Astrophysics Data System (ADS)

Talha Junaid, M.

2017-11-01

This paper presents results of the development and strength properties of ambient-cured alkali activated geopolymer concrete (GPC). The study looks at the strength properties, such as compressive strength, splitting tensile strength, and elastic modulus of such concretes and its dependency on various parameters. The parameters studied in this work are the type and proportions of pre-cursor materials, type of activator and their respective ratios and the curing time. Two types of pre-cursor material; low calcium fly ash (FA) and ground granulated blast furnace slag (GGBFS) were activated using different proportions of sodium silicate and sodium hydroxide solutions. The results indicate that ambient cured geopolymer concrete can be manufactured to match strength properties of ordinary Portland cement concrete (OPC). The strength properties of GPC are dependent on the type and ratio of activator and the proportion of GGBFS used. Increasing the percentage of GGBFS increased the compressive and tensile strengths, while reducing the setting time of the mix. The effect of GGBFS on strength was more pronounced in mixes that contained sodium silicate as activator solution. Unlike OPC, ambient-cured GPC containing sodium silicate gain most of their strength in the first 7 days and there is no change in strength thereafter. However, GPC mixes not containing sodium silicate only achieve a fraction of their strength at 7 days and extended curing is required for such concretes to gain full strength. The results also indicate that the elastic modulus values of GPC mixes without sodium silicate are comparable to OPC while mixes with sodium silicate have elastic modulus values much lower than ordinary concrete.

Occupational protein contact dermatitis from spices in a butcher: a new presentation of the mugwort-spice syndrome.

PubMed

Anliker, Mark David; Borelli, Siegfried; Wüthrich, Brunello

2002-02-01

Protein contact dermatitis to meat is well known in butchers; spices are another source of potential contact allergy and usually are not recognized. We present a first case of contact-dermatitis to spice mix in a 39-year-old-butcher. The patient underwent skin prick testing (SPT) with standard allergens (ALK) and different meat and spice extracts (Stallergènes), scratch-patch testing with spice mix containing glutamate, paprika and other spices. Specific serum-IgE was measured with CAP-FEIA. SPT only showed an immediate-type sensitization to mugwort (+ +), as well as different spices (paprika +, curry +, cumin +) and camomile (+ + +). Scratch-patch tests were negative for different meat, but strongly positive for spice mix (+ + +) after 30 min (wheal and flare) and (+ +) after 48 h (infiltration and vesiculation). Two healthy controls were tested negative for spice mix used from that patient (scratch-patch). Specific IgE was slightly elevated for paprika 0.47 kU/L (CAP class 1), anise 0.43 kU/L, curry 0.36 kU/L and mugwort 3.83 kU/L. Sx1 atopy-multiscreen was 3.8 kU/L due to a sensitization to mugwort alone. The tests performed demonstrate an IgE-mediated contact allergy to spices but also a delayed type allergy to spice mix as a manifestation of the mugwort-spice syndrome in this individual. When testing for occupational dermatitis in butchers, protein contact allergy to spices must also be taken into consideration.

Recycling of mixed wastes using Quantum-CEP{trademark}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sameski, B.

1997-02-01

The author describes the process that M4 Environmental Management, Inc., is commercializing for the treatment of mixed wastes. He summarizes the types of wastes which the process can be applied to, the products which come out of the process, and examples of various waste streams which have been processed. The process is presently licensed to treat mixed wastes and the company has in place contracts for such services. The process uses a molten metal bath to catalyze reactions which break the incoming products down to an atomic level, and allow different process steams to be tapped at the output end.

Methylenetetrahydrofolate reductase and glutathione S-tranferase gene polymorphisms in secondary mixed phenotype acute leukemia: a case report.

PubMed

Skoric, Dejan; Ivana, Joksic; Tanja, Radic; Jovana, Jakovljevic; Petar, Ivanovski; Tatjana, Simic

2014-04-01

Therapy-induced leukemia is a well-known clinical syndrome occurring as a late complication in patients treated with cytotoxic therapy. We herein present results of analysis of common gene polymorphisms in methylenetetrahydrofolate reductase (MTHFR) and glutathione S-transferase (GST) genes in a 10-year-old boy who developed very rare type of cancer, mixed phenotype acute leukemia, 6 years after treatment of acute lymphoblastic leukemia. Impairment in function of GST and MTHFR enzymes found in our patient may have contributed to the development of secondary mixed phenotype acute leukemia, although precise mechanism remains elusive.

Digital sorting of complex tissues for cell type-specific gene expression profiles.

PubMed

Zhong, Yi; Wan, Ying-Wooi; Pang, Kaifang; Chow, Lionel M L; Liu, Zhandong

2013-03-07

Cellular heterogeneity is present in almost all gene expression profiles. However, transcriptome analysis of tissue specimens often ignores the cellular heterogeneity present in these samples. Standard deconvolution algorithms require prior knowledge of the cell type frequencies within a tissue or their in vitro expression profiles. Furthermore, these algorithms tend to report biased estimations. Here, we describe a Digital Sorting Algorithm (DSA) for extracting cell-type specific gene expression profiles from mixed tissue samples that is unbiased and does not require prior knowledge of cell type frequencies. The results suggest that DSA is a specific and sensitivity algorithm in gene expression profile deconvolution and will be useful in studying individual cell types of complex tissues.

TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.

PubMed

James, Bryan D; Wilson, Robert S; Boyle, Patricia A; Trojanowski, John Q; Bennett, David A; Schneider, Julie A

2016-11-01

Hyperphosphorylated transactive response DNA-binding protein 43 (TDP-43, encoded by TARDBP ) proteinopathy has recently been described in ageing and in association with cognitive impairment, especially in the context of Alzheimer's disease pathology. To explore the role of mixed Alzheimer's disease and TDP-43 pathologies in clinical Alzheimer's-type dementia, we performed a comprehensive investigation of TDP-43, mixed pathologies, and clinical Alzheimer's-type dementia in a large cohort of community-dwelling older subjects. We tested the hypotheses that TDP-43 with Alzheimer's disease pathology is a common mixed pathology; is related to increased likelihood of expressing clinical Alzheimer's-type dementia; and that TDP-43 pathologic stage is an important determinant of clinical Alzheimer's-type dementia. Data came from 946 older adults with ( n = 398) and without dementia ( n = 548) from the Rush Memory and Aging Project and Religious Orders Study. TDP-43 proteinopathy (cytoplasmic inclusions) was present in 496 (52%) subjects, and the pattern of deposition was classified as stage 0 (none; 48%), stage 1 (amygdala; 18%), stage 2 (extension to hippocampus/entorhinal; 21%), or stage 3 (extension to neocortex; 14%). TDP-43 pathology combined with a pathologic diagnosis of Alzheimer's disease was a common mixed pathology (37% of all participants), and the proportion of subjects with clinical Alzheimer's-type dementia formerly labelled 'pure pathologic diagnosis of Alzheimer's disease' was halved when TDP-43 was considered. In logistic regression models adjusted for age, sex, and education, TDP-43 pathology was associated with clinical Alzheimer's-type dementia (odds ratio = 1.51, 95% confidence interval = 1.11, 2.05) independent of pathological Alzheimer's disease (odds ratio = 4.30, 95% confidence interval = 3.08, 6.01) or other pathologies (infarcts, arteriolosclerosis, Lewy bodies, and hippocampal sclerosis). Mixed Alzheimer's disease and TDP-43 pathologies were associated with higher odds of clinical Alzheimer's-type dementia (odds ratio = 6.73, 95% confidence interval = 4.18, 10.85) than pathologic Alzheimer's disease alone (odds ratio = 4.62, 95% confidence interval = 2.84, 7.52). In models examining TDP-43 stage, a dose-response relationship with clinical Alzheimer's-type dementia was observed, and a significant association was observed starting at stage 2, extension beyond the amygdala. In this large sample from almost 1000 community participants, we observed that TDP-43 proteinopathy was very common, frequently mixed with pathological Alzheimer's disease, and associated with a higher likelihood of the clinical expression of clinical Alzheimer's-type dementia but only when extended beyond the amygdala. © The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Dealing with gene expression missing data.

PubMed

Brás, L P; Menezes, J C

2006-05-01

Compared evaluation of different methods is presented for estimating missing values in microarray data: weighted K-nearest neighbours imputation (KNNimpute), regression-based methods such as local least squares imputation (LLSimpute) and partial least squares imputation (PLSimpute) and Bayesian principal component analysis (BPCA). The influence in prediction accuracy of some factors, such as methods' parameters, type of data relationships used in the estimation process (i.e. row-wise, column-wise or both), missing rate and pattern and type of experiment [time series (TS), non-time series (NTS) or mixed (MIX) experiments] is elucidated. Improvements based on the iterative use of data (iterative LLS and PLS imputation--ILLSimpute and IPLSimpute), the need to perform initial imputations (modified PLS and Helland PLS imputation--MPLSimpute and HPLSimpute) and the type of relationships employed (KNNarray, LLSarray, HPLSarray and alternating PLS--APLSimpute) are proposed. Overall, it is shown that data set properties (type of experiment, missing rate and pattern) affect the data similarity structure, therefore influencing the methods' performance. LLSimpute and ILLSimpute are preferable in the presence of data with a stronger similarity structure (TS and MIX experiments), whereas PLS-based methods (MPLSimpute, IPLSimpute and APLSimpute) are preferable when estimating NTS missing data.

Geochemical evolution of groundwater in southern Bengal Basin: The example of Rajarhat and adjoining areas, West Bengal, India

NASA Astrophysics Data System (ADS)

Sahu, Paulami; Sikdar, P. K.; Chakraborty, Surajit

2016-02-01

Detailed geochemical analysis of groundwater beneath 1223 km2 area in southern Bengal Basin along with statistical analysis on the chemical data was attempted, to develop a better understanding of the geochemical processes that control the groundwater evolution in the deltaic aquifer of the region. Groundwater is categorized into three types: `excellent', `good' and `poor' and seven hydrochemical facies are assigned to three broad types: `fresh', `mixed' and `brackish' waters. The `fresh' water type dominated with sodium indicates active flushing of the aquifer, whereas chloride-rich `brackish' groundwater represents freshening of modified connate water. The `mixed' type groundwater has possibly evolved due to hydraulic mixing of `fresh' and `brackish' waters. Enrichment of major ions in groundwater is due to weathering of feldspathic and ferro-magnesian minerals by percolating water. The groundwater of Rajarhat New Town (RNT) and adjacent areas in the north and southeast is contaminated with arsenic. Current-pumping may induce more arsenic to flow into the aquifers of RNT and Kolkata cities. Future large-scale pumping of groundwater beneath RNT can modify the hydrological system, which may transport arsenic and low quality water from adjacent aquifers to presently unpolluted aquifer.

Theoretical studies of molecular structure, electronic structure, spectroscopic properties and the ancillary ligand effect: a comparison of tris-chelate ML3-type and ML2X-type species for gallium(III) complexes with N,O-donor phenolic ligand, 2-(2-hydroxyphenyl)benzothiazole.

PubMed

Tong, Yi-Ping; Lin, Yan-Wen

2011-02-01

Two Ga(III) complexes with main ligand, 2-(2-hydroxyphenyl)benzothiazole (HL'), namely mixed-ligand ML2X-type [GaL'2X'] (1) (HX'=acetic acid, as ancillary ligand) and the meridianal tris-chelate [GaL'3] (2) have been investigated by the density functional theory (DFT/TDDFT) level calculations. Both 1 and 2 can be presented as a similar "mixed-ligand ML2X-type" species. The molecular geometries, electronic structures, metal-ligand bonding property of Ga-O (N) (main ligand), Ga-O (N) (ancillary ligand) interactions, and the ancillary ligand effect on their HOMO-LUMO gap, their absorption/emission property, and their absorption/emission wavelengths/colors for them have been discussed in detail based on the orbital interactions, the partial density of states (PDOS), and so on. The current investigation also indicates that it is quite probable that by introduction of different ancillary ligands, a series of new mixed-ligand ML2X-type complexes for group 13 metals can be designed with their absorption/emission property and the absorption/emission wavelengths and colors being tuned. Copyright © 2011 Elsevier B.V. All rights reserved.

The Crystal Structure and Conformations of an Unbranched Mixed Tri-Ubiquitin Chain Containing K48 and K63 Linkages.

PubMed

Padala, Prasanth; Soudah, Nadine; Giladi, Moshe; Haitin, Yoni; Isupov, Michail N; Wiener, Reuven

2017-12-08

The ability of ubiquitin to function in a wide range of cellular processes is ascribed to its capacity to cause a diverse spectrum of modifications. While a target protein can be modified with monoubiquitin, it can also be modified with ubiquitin chains. The latter include seven types of homotypic chains as well as mixed ubiquitin chains. In a mixed chain, not all the isopeptide bonds are restricted to a specific lysine of ubiquitin, resulting in a chain possessing more than one type of linkage. While structural characterization of homotypic chains has been well elucidated, less is known about mixed chains. Here we present the crystal structure of a mixed tri-ubiquitin chain at 3.1-Å resolution. In the structure, the proximal ubiquitin is connected to the middle ubiquitin via K48 and these two ubiquitins adopt a compact structure as observed in K48 di-ubiquitin. The middle ubiquitin links to the distal ubiquitin via its K63 and these ubiquitins adopt two conformations, suggesting a flexible structure. Using small-angle X-ray scattering, we unexpectedly found differences between the conformational ensembles of the above tri-ubiquitin chains and chains possessing the same linkages but in the reverse order. In addition, cleavage of the K48 linkage by DUB is faster if this linkage is at the distal end. Taken together, our results suggest that in mixed chains, not only the type of the linkages but also their sequence determine the structural and functional properties of the chain. Copyright © 2017 Elsevier Ltd. All rights reserved.

Measuring mixing efficiency in experiments of strongly stratified turbulence

NASA Astrophysics Data System (ADS)

Augier, P.; Campagne, A.; Valran, T.; Calpe Linares, M.; Mohanan, A. V.; Micard, D.; Viboud, S.; Segalini, A.; Mordant, N.; Sommeria, J.; Lindborg, E.

2017-12-01

Oceanic and atmospheric models need better parameterization of the mixing efficiency. Therefore, we need to measure this quantity for flows representative of geophysical flows, both in terms of types of flows (with vortices and/or waves) and of dynamical regimes. In order to reach sufficiently large Reynolds number for strongly stratified flows, experiments for which salt is used to produce the stratification have to be carried out in a large rotating platform of at least 10-meter diameter.We present new experiments done in summer 2017 to study experimentally strongly stratified turbulence and mixing efficiency in the Coriolis platform. The flow is forced by a slow periodic movement of an array of large vertical or horizontal cylinders. The velocity field is measured by 3D-2C scanned horizontal particles image velocimetry (PIV) and 2D vertical PIV. Six density-temperature probes are used to measure vertical and horizontal profiles and signals at fixed positions.We will show how we rely heavily on open-science methods for this study. Our new results on the mixing efficiency will be presented and discussed in terms of mixing parameterization.

Postprandial glucose and insulin levels in type 2 diabetes mellitus patients after consumption of ready-to-eat mixed meals.

PubMed

Manios, Yannis; Moschonis, George; Mavrogianni, Christina; Tsoutsoulopoulou, Konstantina; Kogkas, Stergios; Lambrinou, Christina-Paulina; Efstathopoulou, Eirini

2017-04-01

To compare the effects of three ready-to-eat mixed meals, with a high fiber content and low glycemic index, on postprandial glycemic and insulinemic response in patients with Type 2 diabetes mellitus (T2DM). The current study followed a prospective, three-way, cross-over design. Twenty-four patients with T2DM consumed three ready-to-eat mixed meals, i.e., "wild greens pie" (meal 1), "chicken burgers with boiled vegetables" (meal 2) and "vegetable moussaka" (meal 3) and an oral glucose load, all providing 50 g of carbohydrates. Venous blood was collected at 0, 30, 60, 90 and 120 min postprandial. Statistical analyses included repeated measures analysis of variance and calculations of the area under the glucose and insulin curves (AUC) for each one of the test meals and the oral glucose load. Patients consuming each one of the three mixed meals showed better postprandial glycemic responses compared to the oral glucose load (P < 0.001). Furthermore, patients consuming meal 3 showed a better insulinemic response compared to the oral glucose load and meal 1, after 60 and 120 min postprandial, respectively (P < 0.05). In addition, the increase observed in HOMA-IR values from T0 to T120 was significantly lower for meal 3, compared to the oral glucose load (P < 0.001). The three ready-to-eat mixed meals examined in the present study were found to elicit significantly lower glycemic responses compared to the oral glucose load in diabetic patients. The mixed meals examined in the present study could be proposed as effective, palatable and practical solutions for diabetics for glucose control.

Mechanical properties of 0.40 pct C-Ni-Cr-Mo high strength steel having a mixed structure of martensite and bainite

NASA Astrophysics Data System (ADS)

Tomita, Yoshiyuki; Okabayashi, Kunio

1985-01-01

A study has been systematically made of the effect of bainite on the mechanical properties of a commercial Japanese 0.40 pct C-Ni-Cr-Mo high strength steel (AISI 4340 type) having a mixed structure of martensite and bainite. Isothermal transformation of lower bainite at 593 K, which appeared in acicular form and partitioned prior austenite grains, in association with tempered marprovided provided a better combination of strength and fracture ductility, improving true notch tensile strength (TNTS) and fracture appearance transition temperature (FATT) in Charpy impact tests. This occurred regardless of the volume fraction of lower bainite present and/or the tempering conditions employed to create a difference in strength between the two phases. Upper bainite which was isothermally transformed at 673 K appeared as masses that filled prior austenite grains and had a very detrimental effect on the strength and fracture ductility of the steel. Significant damage occurred to TNTS and FATT, irrespective of the volume fraction of upper bainite present and/or the tempering conditions employed when the upper bainite was associated with tempered martensite. However, when the above two types of bainite appeared in the same size, shape, and distribution within tempered martensite approximately equalized to the strength of the bainite, a similar trend or a marked similarity was observed between the tensile properties of the mixed structures and the volume fraction of bainite. From the above results, it is assumed that the mechanical properties of high strength steels having a mixed structure of martensite and bainite are affected more strongly by the size, shape, and distribution of bainite within martensite than by the difference in strength between martensite and bainite or by the type of mixed bainite present. The remarkable effects of the size, shape, and distribution of bainite within martensite on the mechanical properties of the steel are briefly discussed in terms of the modified law of mixtures, metallographic examinations, and the analyses of stress-strain diagrams.

Electrical detection and quantification of single and mixed DNA nucleotides in suspension

NASA Astrophysics Data System (ADS)

Ahmad, Mahmoud Al; Panicker, Neena G.; Rizvi, Tahir A.; Mustafa, Farah

2016-09-01

High speed sequential identification of the building blocks of DNA, (deoxyribonucleotides or nucleotides for short) without labeling or processing in long reads of DNA is the need of the hour. This can be accomplished through exploiting their unique electrical properties. In this study, the four different types of nucleotides that constitute a DNA molecule were suspended in a buffer followed by performing several types of electrical measurements. These electrical parameters were then used to quantify the suspended DNA nucleotides. Thus, we present a purely electrical counting scheme based on the semiconductor theory that allows one to determine the number of nucleotides in a solution by measuring their capacitance-voltage dependency. The nucleotide count was observed to be similar to the multiplication of the corresponding dopant concentration and debye volume after de-embedding the buffer contribution. The presented approach allows for a fast and label-free quantification of single and mixed nucleotides in a solution.

Selection of latent variables for multiple mixed-outcome models

PubMed Central

ZHOU, LING; LIN, HUAZHEN; SONG, XINYUAN; LI, YI

2014-01-01

Latent variable models have been widely used for modeling the dependence structure of multiple outcomes data. However, the formulation of a latent variable model is often unknown a priori, the misspecification will distort the dependence structure and lead to unreliable model inference. Moreover, multiple outcomes with varying types present enormous analytical challenges. In this paper, we present a class of general latent variable models that can accommodate mixed types of outcomes. We propose a novel selection approach that simultaneously selects latent variables and estimates parameters. We show that the proposed estimator is consistent, asymptotically normal and has the oracle property. The practical utility of the methods is confirmed via simulations as well as an application to the analysis of the World Values Survey, a global research project that explores peoples’ values and beliefs and the social and personal characteristics that might influence them. PMID:27642219

Comparing the Effects of Negative and Mixed Emotional Messages on Predicted Occasional Excessive Drinking

PubMed Central

Carrera, Pilar; Caballero, Amparo; Muñoz, Dolores

2008-01-01

In this work we present two types of emotional message, negative (sadness) versus mixed (joy and sadness), with the aim of studying their differential effect on attitude change and the probability estimated by participants of repeating the behavior of occasional excessive drinking in the near future. The results show that for the group of participants with moderate experience in this behavior the negative message, compared to the mixed one, is associated with higher probability of repeating the risk behavior and a less negative attitude toward it. These results suggest that mixed emotional messages (e.g. joy and sadness messages) could be more effective in campaigns for the prevention of this risk behavior. PMID:25977606

Is pacemaker therapy the right key to patients with vasovagal syncope?

PubMed

Radovanović, Nikola N; Kirćanski, Bratislav; Raspopović, Srdjan; Pavlović, Siniša U; Jovanović, Velibor; Milašinović, Goran

2016-01-01

Vasovagal syncope is the most common type of reflex syncope. Efficacy of cardiac pacing in this indication has not been the subject of many studies and pacemaker therapy in patients with vasovagal syncope is still controversial. This study aimed to assess the efficacy and safety of pacing therapy in treatment of patients with vasovagal syncope, to determine contribution of new therapeutic models in increasing its success, and to identify risk factors associated with a higher rate of symptoms after pacemaker implantation. A retrospective study included 30 patients with pacemaker implanted due to vasovagal syncope in the Pacemaker Center, Clinical Center of Serbia, between November 2003 and June 2014. Head-up tilt test was performed to diagnose vasovagal syncope. Patients with cardioinhibitory and mixed type of disease were enrolled in the study. Mean age was 48.1 ± 11.1 years and 18 (60%) patients were men. Mean follow-up period was 5.9 ± 3.0 years. Primarily, implantable loop recorder was implanted in 10 (33.3%) patients. Twenty (66.7%) patients presented cardioinhibitory and 10 (33.3%) mixed type of vasovagal syncope. After pacemaker implantation, 11 (36.7%) patients had syncope. In multiple logistic regression analysis we showed that syncope is statistically more likely to occur after pacemaker implantation in patients with mixed type of vasovagal syncope (p = 0.018). There were two (6.7%) perioperative surgical complications. Pacemaker therapy is a safe treatment for patients with vasovagal syncope, whose efficacy can be improved by strict selection of patients. We showed that symptoms occur statistically more often in patients with mixed type of disease after pacemaker implantation.

Numerical solution of nonlinear partial differential equations of mixed type. [finite difference approximation

NASA Technical Reports Server (NTRS)

Jameson, A.

1976-01-01

A review is presented of some recently developed numerical methods for the solution of nonlinear equations of mixed type. The methods considered use finite difference approximations to the differential equation. Central difference formulas are employed in the subsonic zone and upwind difference formulas are used in the supersonic zone. The relaxation method for the small disturbance equation is discussed and a description is given of difference schemes for the potential flow equation in quasi-linear form. Attention is also given to difference schemes for the potential flow equation in conservation form, the analysis of relaxation schemes by the time dependent analogy, the accelerated iterative method, and three-dimensional calculations.

Optical coherence tomography characteristics of different types of big bubbles seen in deep anterior lamellar keratoplasty by the big bubble technique

PubMed Central

AlTaan, S L; Termote, K; Elalfy, M S; Hogan, E; Werkmeister, R; Schmetterer, L; Holland, S; Dua, H S

2016-01-01

Purpose To define optical coherence tomography (OCT) characteristics of type-1, type-2, and mixed big bubbles (BB) seen in deep anterior lamellar keratoplasty. Methods Human sclero-corneal discs were obtained from UK (30) and Canada (16) eye banks. Air was injected into corneal stroma until a BB formed. UK samples were fixed in formalin before scanning with Fourier-domain (FD-OCT). One pair of each type of BB was scanned fresh. All BB obtained from Canada were scanned fresh with time-domain (TD-OCT). For each OCT machine used, type-1 BB from which Descemets membrane (DM) was partially peeled, were also scanned. The morphological characteristics of the scans were studied. Results FD-OCT of the posterior wall of type-1 (Dua's layer (DL) with DM) and type-2 BB (DM alone) both revealed a double-contour hyper-reflective curvilinear image with a hypo-reflective zone in between. The anterior line of type-2 BB was thinner than that seen with type-1 BB. In mixed BB, FD-OCT showed two separate curvilinear images. The anterior image was a single hyper-reflective line (DL), whereas the posterior image, representing the posterior wall of type-2 BB (DM) was made of two hyper-reflective lines with a dark space in between. TD-OCT images were similar with less defined component lines, but the entire extent of the BB could be visualised. Conclusion On OCT examination the DM and DL present distinct features, which can help identify type-1, type-2, and mixed BB. These characteristics will help corneal surgeons interpret intraoperative OCT during lamellar corneal surgery. PMID:27472215

Mixing and diffusion in a two-type population.

PubMed

Izquierdo, Segismundo S; Izquierdo, Luis R; López-Pintado, Dunia

2018-02-01

The outbreak of epidemics, the rise of religious radicalization or the motivational influence of fellow students in classrooms are some of the issues that can be described as diffusion processes in heterogeneous groups. Understanding the role that interaction patterns between groups (e.g. homophily or segregation) play in the diffusion of certain traits or behaviours is a major challenge for contemporary societies. Here, we study the impact on diffusion processes of mixing (or, alternatively, segregating) two groups that present different sensitivities or propensities to contagion. We find non-monotonic effects of mixing and inefficient segregation levels, i.e. situations where a change in the mixing level can benefit both groups, e.g. where an increase in the mixing level can reduce the expected contagion levels in both groups. These findings can have fundamental consequences for the design of inclusion policies.

Mixing and diffusion in a two-type population

PubMed Central

López-Pintado, Dunia

2018-01-01

The outbreak of epidemics, the rise of religious radicalization or the motivational influence of fellow students in classrooms are some of the issues that can be described as diffusion processes in heterogeneous groups. Understanding the role that interaction patterns between groups (e.g. homophily or segregation) play in the diffusion of certain traits or behaviours is a major challenge for contemporary societies. Here, we study the impact on diffusion processes of mixing (or, alternatively, segregating) two groups that present different sensitivities or propensities to contagion. We find non-monotonic effects of mixing and inefficient segregation levels, i.e. situations where a change in the mixing level can benefit both groups, e.g. where an increase in the mixing level can reduce the expected contagion levels in both groups. These findings can have fundamental consequences for the design of inclusion policies. PMID:29515903

Numerical investigation on layout optimization of obstacles in a three-dimensional passive micromixer.

PubMed

Chen, Xueye; Zhao, Zhongyi

2017-04-29

This paper aims at layout optimization design of obstacles in a three-dimensional T-type micromixer. Numerical analysis shows that the direction of flow velocity change constantly due to the obstacles blocking, which produces the chaotic convection and increases species mixing effectively. The orthogonal experiment method was applied for determining the effects of some key parameters on mixing efficiency. The weights in the order are: height of obstacles > geometric shape > symmetry = number of obstacles. Based on the optimized results, a multi-units obstacle micromixer was designed. Compared with T-type micromixer, the multi-units obstacle micromixer is more efficient, and more than 90% mixing efficiency were obtained for a wide range of peclet numbers. It can be demonstrated that the presented optimal design method of obstacles layout in three-dimensional microchannels is a simple and effective technology to improve species mixing in microfluidic devices. The obstacles layout methodology has the potential for applications in chemical engineering and bioengineering. Copyright © 2017 Elsevier B.V. All rights reserved.

Mechanical Chevrons and Fluidics for Advanced Military Aircraft Noise Reduction

DTIC Science & Technology

2011-03-01

at or near the nozzle lip. Therefore, for the problem at hand, the simulations will need to accurately capture shock waves , unsteady large-scale...simulations could accurately capture the flow field and near-field noise from representative jet engine nozzles and indeed this was a go/no-go...mixing noise. The first two types of noise are related to the shock waves that are present in the high-speed jet flow. While the mixing noise

Active Detection of Shielded Special Nuclear Material in the Presence of Variable High Backgrounds Using a Mixed Photon-Neutron Source

NASA Astrophysics Data System (ADS)

Martin, Philip N.; Clemett, Ceri D.; Hill, Cassie; O'Malley, John; Campbell, Ben

This paper describes and compares two approaches to the analysis of active interrogation data containing high photon backgrounds associated with mixed photon-neutron source flash active interrogation. Results from liquid scintillation detectors (EJ301/EJ309) fielded at the Naval Research Laboratory (NRL), in collaboration with the Atomic Weapons Establishment (AWE), using the NRL Mercury Inductive Voltage Adder (IVA) operating in both a photon and mixed photon-neutron mode at a Depleted Uranium (DU) target are presented. The standard approach applying a Figure of Merit (FOM) consisting of background sigma above background is compared with an approach looking to fit only the time-decaying photon signal with standard delayed photon emission from ∼10-MeV end-point-energy Bremsstrahlung photofission of DU. Examples where each approach does well and less well are presented together with a discussion of the relative limitations of both approaches to the type of mixed photon-neutron flash active interrogation being considered.

Mixed acinar-neuroendocrine-ductal carcinoma of the pancreas: a tale of three lineages.

PubMed

Anderson, Mark J; Kwong, Christina A; Atieh, Mohammed; Pappas, Sam G

2016-06-02

Most pancreatic cancers arise from a single cell type, although mixed pancreatic carcinomas represent a rare exception. The rarity of these aggressive malignancies and the limitations of fine-needle aspiration (FNA) pose significant barriers to diagnosis and appropriate management. We report a case of a 54-year-old man presenting with abdominal pain, jaundice and a hypodense lesion within the uncinate process on CT. FNA suggested poorly differentiated adenocarcinoma, which was subsequently resected via pancreaticoduodenectomy. Pathological analysis yielded diagnosis of invasive mixed acinar-neuroendocrine-ductal pancreatic carcinoma. Given the rare and deadly nature of these tumours, clinicians must be aware of their pathophysiology and do practice with a high degree of clinical suspicion, when appropriate. Surgical resection and thorough pathological analysis with immunohistochemical staining and electron microscopy remain the standards of care for mixed pancreatic tumours without gross evidence of metastasis. Diligent characterisation of the presentation and histological findings associated with these neoplasms should continue in order to promote optimal diagnostic and therapeutic strategies. 2016 BMJ Publishing Group Ltd.

First experimental test of a trace formula for billiard systems showing mixed dynamics.

PubMed

Dembowski, C; Gräf, H D; Heine, A; Hesse, T; Rehfeld, H; Richter, A

2001-04-09

In general, trace formulas relate the density of states for a given quantum mechanical system to the properties of the periodic orbits of its classical counterpart. Here we report for the first time on a semiclassical description of microwave spectra taken from superconducting billiards of the Limaçon family showing mixed dynamics in terms of a generalized trace formula derived by Ullmo et al. [Phys. Rev. E 54, 136 (1996)]. This expression not only describes mixed-typed behavior but also the limiting cases of fully regular and fully chaotic systems and thus presents a continuous interpolation between the Berry-Tabor and Gutzwiller formulas.

Vapor-liquid equilibria for hydrogen fluoride + 1,1-difluoroethane at 288.23 and 298.35 K

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, J.; Kim, H.; Lim, J.S.

1997-07-01

Isothermal vapor-liquid equilibria for hydrogen fluoride + 1,1-difluoroethane at 288.23 and 298.35 K were measured using a circulation type apparatus equipped with an equilibrium view cell. The compositions of both vapor and liquid phases were analyzed by an on-line gas chromatographic method. They were compared with PTx equilibrium data measured by the total pressure method. The experimental data were correlated with Anderko`s equation of state using the Wong-Sandler mixing rule as well as the van der Waals one-fluid mixing rule. The Wong-Sandler mixing rule gives better results, and the relevant parameters are presented.

Enterovirus D68

MedlinePlus

... EV-D68 outbreak this year or in future years? Enteroviruses are ever-present in the community. We can’t predict whether EV-D68 will be a common type of enterovirus detected this year or in other future seasons. A mix of ...

Qualifying Items of Work for End-Result Specifications

DOT National Transportation Integrated Search

1997-07-01

The Texas Department of Transportation (TxDOT) is presently using a performance-based specification for hot-mix asphalt concrete pavement. There is a strong interest in determining if other construction items can be converted into this type of specif...

Larviculture of a carnivorous freshwater catfish, Lophiosilurus alexandri, screened by personality type.

PubMed

Torres, Isabela F Araújo; Júlio, Gustavo S da C; Figueiredo, Luis Gustavo; de Lima, Natália L C; Soares, Ana Paula N; Luz, Ronald K

2017-12-01

Considering that each personality type in animals presents distinct physiological and behavioural responses, this study evaluated the efficiency of the Novel Environment test to classify larvae of Lophiosilurus alexandri into bold and shy individuals, which were then investigated for growth, cannibalism and mortality in larviculture of pure and mixed groups. Larvae with an average weight of 24.0±1.7mg and length of 14.1±0.4mm, were subjected to a Novel Environment test to classify their personality type (bold and shy larvae). After the larvae were classified according to personality type, they were subjected to larviculture for 15days. Three treatments were tested: only bold larvae, only shy larvae, and a mixed treatment (bold larvae+shy larvae) at a density for 16 larvae/L, which were fed 3 times a day with Artemia nauplii. After larviculture, there were no differences in the final lengths of larvae of the bold, shy, and mixed treatments (26.9±0.76mm, 26.7±1.00mm, and 26.8±1.24mm, respectively); however, shy larvae possessed weighed less (0.22±0.01g) than the bold and mixed treatments, which did not differ significantly (0.25±0.02g and 0.27±0.02g, respectively). The bold and mixed treatments had the highest cannibalism rate (11.2±5.1% and 23.1±12.3%, respectively). Overall survival was lowest in the mixed treatment (62.5±13.0%), while that of the bold and shy treatments were similar (82.5±9.2% and 86.2±9.2%, respectively). The separation of L. alexandri larvae by traits can ensure a decrease in cannibalism and hence, more productive larviculture. Copyright © 2017 Elsevier B.V. All rights reserved.

Cell-type-specific and differentiation-status-dependent variations in cytotoxicity of tributyltin in cultured rat cerebral neurons and astrocytes.

PubMed

Oyanagi, Koshi; Tashiro, Tomoko; Negishi, Takayuki

2015-08-01

Tributyltin (TBT) is an organotin used as an anti-fouling agent for fishing nets and ships and it is a widespread environmental contaminant at present. There is an increasing concern about imperceptible but serious adverse effect(s) of exposure to chemicals existing in the environment on various organs and their physiological functions, e.g. brain and mental function. Here, so as to contribute to improvement of and/or advances in in vitro cell-based assay systems for evaluating brain-targeted adverse effect of chemicals, we tried to evaluate cell-type-specific and differentiation-status-dependent variations in the cytotoxicity of TBT towards neurons and astrocytes using the four culture systems differing in the relative abundance of these two types of cells; primary neuron culture (> 95% neurons), primary neuron-astrocyte (2 : 1) mix culture, primary astrocyte culture (> 95% astrocytes), and passaged astrocyte culture (100% proliferative astrocytes). Cell viability was measured at 48 hr after exposure to TBT in serum-free medium. IC50's of TBT were 198 nM in primary neuron culture, 288 nM in primary neuron-astrocyte mix culture, 2001 nM in primary astrocyte culture, and 1989 nM in passaged astrocyte culture. Furthermore, in primary neuron-astrocyte mix culture, vulnerability of neurons cultured along with astrocytes to TBT toxicity was lower than that of neurons cultured purely in primary neuron culture. On the other hand, astrocytes in primary neuron-astrocyte mix culture were considered to be more vulnerable to TBT than those in primary or passaged astrocyte culture. The present study demonstrated variable cytotoxicity of TBT in neural cells depending on the culture condition.

[The dry binders, Vivapur 102, Vivapur 12 and the effect of magnesium stearate on the strength of tablets containing these substances].

PubMed

Muzíková, J; Horácek, J

2003-07-01

Vivapur is microcrystalline cellulose manufactured by the German firm J. Rettenmeier & Söhne GmbH + Co. The types Vivapur 102 and 12 enjoy priority use as dry binders for direct tablet compression. The present paper evaluates tensile strength of tablets made from these substances and the effect of an addition of the lubricant magnesium stearate in connection with its concentration and the conditions of the process of mixing, particularly the period and intensity of mixing. The tested concentrations of stearate were 0.4 and 0.8%, the tested periods of mixing being 2.5, 5, 10, and 20 minutes, intensities of mixing 17 and 34 rot./min. Sensitivity of dry binders to added stearate was evaluated by means of the LSR (lubricant sensitivity ratio) values. The results demonstrated higher sensitivity to an addition of the lubricant in Vivapur 12 than in Vivapur 102. In the first part of the paper focused on the effect of stearate concentration on tensile strength of tablets, Vivapur 102 was also compared with Avicel PH-102. Tablets from Vivapur 102 alone were stronger than those from Avicel PH-102. A concentration of stearate of 0.8% decreased the binding capacity of Vivapur 102 more than that of Avicel PH-102. With a prolonged period of mixing and increased intensity of mixing with stearate, tensile strength of tablets from both Vivapur types was decresed, and a prolonged period of mixing exerted a more marked effect on Vivapur 12 and increased intensity of mixing, on Vivapur 102.

Titanite-scale insights into multi-stage magma mixing in Early Cretaceous of NW Jiaodong terrane, North China Craton

NASA Astrophysics Data System (ADS)

Jiang, Peng; Yang, Kui-Feng; Fan, Hong-Rui; Liu, Xuan; Cai, Ya-Chun; Yang, Yue-Heng

2016-08-01

The Early Cretaceous Guojialing-type granodiorites in northwestern Jiaodong terrane carry significant records for strong mantle-crust interaction during the destruction of North China Craton (NCC); however, the definite petrogenetic mechanism and detailed magmatic process remain an enigma. Titanite in igneous rocks can serve as an effective petrogenetic indicator. Here, we present integrated geochronological and geochemical studies on titanites from Guojialing-type granodiorites and their dioritic enclaves to constrain their petrogenesis. Titanites from granodiorites (G-type) and plagioclase-rich dioritic enclaves (E-type-I) present an identical U-Pb age ( 130 Ma) and an indistinguishable wide range of Zr and total REEs contents, and Th/U ratios. However, these two types of titanites exhibit distinct micro-scale textures and geochemical compositions. G-type titanites are characterized by oscillatory zonings with two Light BSE zones (LBZ) and two or three dark BSE zones, whereas E-type-I titanites are marked by core-mantle-rim zonings. Drastic increase of LREEs, Zr, Hf, and Fe and decrease of Nb, Ta, Al, and F contents are observed in LBZ of G-type titanites, whereas remarkable reduction of LREEs, Zr, and Hf and elevation of F contents are observed from the cores to the mantles of E-type-I titanites. Based on Zr-in-titanite thermometry, G-type titanites are interpreted to have experienced twice notable temperature increase, while E-type-I titanites are inferred to have undergone a rapid cooling process. Furthermore, we suggest that the drastic chemical changes in G-type and E-type-I titanites are ascribed to early-stage magma mixing between a colder felsic magma and a Fe-, REE-rich hotter dioritic magma. Compared to G-type and E-type-I titanites, titanites from plagioclase-poor dioritic enclaves (E-type-II) are characterized by their occurrence in interstitial space and present a relatively younger U-Pb age ( 128 Ma) and much narrower and lower range of Zr, total REEs contents, and Th/U ratios, but reveal high F contents (0.35-0.76 wt.%) and extreme high Nb/Ta ratios (up to 65.6). Such titanites are perceived to record late-stage mingling, during which F-rich and REE-poor hybrid granodioritic magma squeezed into the incompletely consolidated dioritic enclaves with accompanying fluid-rock interaction. Combining our results with previous isotopic studies, a new genetic model for Guojialing-type granodiorites is envisaged, which involves multi-stage magma mixing between Archean lower crust-derived felsic magma and mafic lower crust-derived dioritic magma, triggered by mantle-derived mafic magma underplating during the course of asthenospheric upwelling in Early Cretaceous. Such process further implicates the reactivation of Jiaodong lower crust during the destruction of NCC.

Classification of Arctic, midlatitude and tropical clouds in the mixed-phase temperature regime

NASA Astrophysics Data System (ADS)

Costa, Anja; Meyer, Jessica; Afchine, Armin; Luebke, Anna; Günther, Gebhard; Dorsey, James R.; Gallagher, Martin W.; Ehrlich, Andre; Wendisch, Manfred; Baumgardner, Darrel; Wex, Heike; Krämer, Martina

2017-10-01

The degree of glaciation of mixed-phase clouds constitutes one of the largest uncertainties in climate prediction. In order to better understand cloud glaciation, cloud spectrometer observations are presented in this paper, which were made in the mixed-phase temperature regime between 0 and -38 °C (273 to 235 K), where cloud particles can either be frozen or liquid. The extensive data set covers four airborne field campaigns providing a total of 139 000 1 Hz data points (38.6 h within clouds) over Arctic, midlatitude and tropical regions. We develop algorithms, combining the information on number concentration, size and asphericity of the observed cloud particles to classify four cloud types: liquid clouds, clouds in which liquid droplets and ice crystals coexist, fully glaciated clouds after the Wegener-Bergeron-Findeisen process and clouds where secondary ice formation occurred. We quantify the occurrence of these cloud groups depending on the geographical region and temperature and find that liquid clouds dominate our measurements during the Arctic spring, while clouds dominated by the Wegener-Bergeron-Findeisen process are most common in midlatitude spring. The coexistence of liquid water and ice crystals is found over the whole mixed-phase temperature range in tropical convective towers in the dry season. Secondary ice is found at midlatitudes at -5 to -10 °C (268 to 263 K) and at higher altitudes, i.e. lower temperatures in the tropics. The distribution of the cloud types with decreasing temperature is shown to be consistent with the theory of evolution of mixed-phase clouds. With this study, we aim to contribute to a large statistical database on cloud types in the mixed-phase temperature regime.

To mix or not to mix venous blood samples collected in vacuum tubes?

PubMed

Parenmark, Anna; Landberg, Eva

2011-09-08

There are recommendations to mix venous blood samples by inverting the tubes immediately after venipuncture. Though mixing allows efficient anticoagulation in plasma tubes and fast initiation of coagulation in serum tubes, the effect on laboratory analyses and risk of haemolysis has not been thoroughly evaluated. Venous blood samples were collected by venipuncture in vacuum tubes from 50 patients (10 or 20 patients in each group). Four types of tubes and 18 parameters used in routine clinical chemistry were evaluated. For each patient and tube, three types of mixing strategies were used: instant mixing, no mixing and 5 min of rest followed by mixing. Most analyses did not differ significantly in samples admitted to different mixing strategies. Plasma lactate dehydrogenase and haemolysis index showed a small but significant increase in samples omitted to instant mixing compared to samples without mixing. However, in one out of twenty non-mixed samples, activated partial thromboplastin time was seriously affected. These results indicate that mixing blood samples after venipuncture is not mandatory for all types of tubes. Instant mixing may introduce interference for those analyses susceptible to haemolysis. However, tubes with liquid-based citrate buffer for coagulation testing should be mixed to avoid clotting.

Molecular Analysis of Mixed Endometrial Carcinomas Shows Clonality in Most Cases.

PubMed

Köbel, Martin; Meng, Bo; Hoang, Lien N; Almadani, Noorah; Li, Xiaodong; Soslow, Robert A; Gilks, C Blake; Lee, Cheng-Han

2016-02-01

Mixed endometrial carcinoma refers to a tumor that comprises 2 or more distinct histotypes. We studied 18 mixed-type endometrial carcinomas-11 mixed serous and low-grade endometrioid carcinomas (SC/EC), 5 mixed clear cell and low-grade ECs (CCC/EC), and 2 mixed CCC and SCs (CCC/SC), using targeted next-generation sequencing and immunohistochemistry to compare the molecular profiles of the different histotypes present in each case. In 16 of 18 cases there was molecular evidence that both components shared a clonal origin. Eight cases (6 EC/SC, 1 EC/CCC, and 1 SC/CCC) showed an SC molecular profile that was the same in both components. Five cases (3 CCC/EC and 2 SC/EC) showed a shared endometrioid molecular profile and identical mismatch-repair protein deficiency in both components. A single SC/EC case harbored the same POLE exonuclease domain mutation in both components. One SC/CCC and 1 EC/CCC case showed both shared and unique molecular features in the 2 histotype components, suggesting early molecular divergence from a common clonal origin. In 2 cases, there were no shared molecular features, and these appear to be biologically unrelated synchronous tumors. Overall, these results show that the different histologic components in mixed endometrial carcinomas typically share the same molecular aberrations. Mixed endometrial carcinomas most commonly occur through morphologic mimicry, whereby tumors with serous-type molecular profile show morphologic features of EC or CCC, or through underlying deficiency in DNA nucleotide repair, with resulting rapid accrual of mutations and intratumoral phenotypic heterogeneity. Less commonly, mixed endometrial carcinomas are the result of early molecular divergence from a common progenitor clone or are synchronous biologically unrelated tumors (collision tumors).

Molecular analysis of mixed endometrial carcinomas shows clonality in most cases

PubMed Central

Hoang, Lien N.; Almadani, Noorah; Li, Xiaodong; Soslow, Robert A; Gilks, C. Blake; Lee, Cheng-Han

2016-01-01

Mixed endometrial carcinoma refers to a tumor that is comprised of two or more distinct histotypes. We studied 18 mixed-type endometrial carcinomas - 11 mixed serous and low-grade endometrioid carcinomas (SC/EC), 5 mixed clear cell and low-grade endometrioid carcinomas (CCC/EC), and 2 mixed clear cell and serous carcinoma (CCC/SC), using targeted next generation sequencing and immunohistochemistry to compare the molecular profiles of the different histotypes present in each case. In 16 of 18 cases there was molecular evidence that both components shared a clonal origin. Eight cases (6 EC/SC, 1 EC/CCC and 1 SC/CCC) showed a serous carcinoma molecular profile that was the same in both components. Five cases (3 CCC/EC and 2 SC/EC) showed a shared endometrioid molecular profile and identical mismatch repair protein (MMR) deficiency in both components. A single SC/EC case harbored the same POLE exonuclease domain mutation in both components. One SC/CCC and one EC/CCC case showed both shared and unique molecular features in the two histotype components, suggesting early molecular divergence from a common clonal origin. In two cases, there were no shared molecular features and these appear to be biologically unrelated synchronous tumors. Overall, these results show that the different histologic components in mixed endometrial carcinomas typically share the same molecular aberrations. Mixed endometrial carcinomas most commonly occur through morphological mimicry, whereby tumors with serous-type molecular profile show morphological features of endometrioid or clear cell carcinoma, or through underlying deficiency in DNA nucleotide repair, with resulting rapid accrual of mutations and intratumoral phenotypic heterogeneity. Less commonly, mixed endometrial carcinomas are the result of early molecular divergence from a common progenitor clone or are synchronous biologically unrelated tumors (collision tumors). PMID:26492180

Mixing Single Scattering Properties in Vector Radiative Transfer for Deterministic and Stochastic Solutions

NASA Astrophysics Data System (ADS)

Mukherjee, L.; Zhai, P.; Hu, Y.; Winker, D. M.

2016-12-01

Among the primary factors, which determine the polarized radiation, field of a turbid medium are the single scattering properties of the medium. When multiple types of scatterers are present, the single scattering properties of the scatterers need to be properly mixed in order to find the solutions to the vector radiative transfer theory (VRT). The VRT solvers can be divided into two types: deterministic and stochastic. The deterministic solver can only accept one set of single scattering property in its smallest discretized spatial volume. When the medium contains more than one kind of scatterer, their single scattering properties are averaged, and then used as input for the deterministic solver. The stochastic solver, can work with different kinds of scatterers explicitly. In this work, two different mixing schemes are studied using the Successive Order of Scattering (SOS) method and Monte Carlo (MC) methods. One scheme is used for deterministic and the other is used for the stochastic Monte Carlo method. It is found that the solutions from the two VRT solvers using two different mixing schemes agree with each other extremely well. This confirms the equivalence to the two mixing schemes and also provides a benchmark for the VRT solution for the medium studied.

The maximum specific hydrogen-producing activity of anaerobic mixed cultures: definition and determination

PubMed Central

Mu, Yang; Yang, Hou-Yun; Wang, Ya-Zhou; He, Chuan-Shu; Zhao, Quan-Bao; Wang, Yi; Yu, Han-Qing

2014-01-01

Fermentative hydrogen production from wastes has many advantages compared to various chemical methods. Methodology for characterizing the hydrogen-producing activity of anaerobic mixed cultures is essential for monitoring reactor operation in fermentative hydrogen production, however there is lack of such kind of standardized methodologies. In the present study, a new index, i.e., the maximum specific hydrogen-producing activity (SHAm) of anaerobic mixed cultures, was proposed, and consequently a reliable and simple method, named SHAm test, was developed to determine it. Furthermore, the influences of various parameters on the SHAm value determination of anaerobic mixed cultures were evaluated. Additionally, this SHAm assay was tested for different types of substrates and bacterial inocula. Our results demonstrate that this novel SHAm assay was a rapid, accurate and simple methodology for determining the hydrogen-producing activity of anaerobic mixed cultures. Thus, application of this approach is beneficial to establishing a stable anaerobic hydrogen-producing system. PMID:24912488

The maximum specific hydrogen-producing activity of anaerobic mixed cultures: definition and determination

NASA Astrophysics Data System (ADS)

Mu, Yang; Yang, Hou-Yun; Wang, Ya-Zhou; He, Chuan-Shu; Zhao, Quan-Bao; Wang, Yi; Yu, Han-Qing

2014-06-01

Fermentative hydrogen production from wastes has many advantages compared to various chemical methods. Methodology for characterizing the hydrogen-producing activity of anaerobic mixed cultures is essential for monitoring reactor operation in fermentative hydrogen production, however there is lack of such kind of standardized methodologies. In the present study, a new index, i.e., the maximum specific hydrogen-producing activity (SHAm) of anaerobic mixed cultures, was proposed, and consequently a reliable and simple method, named SHAm test, was developed to determine it. Furthermore, the influences of various parameters on the SHAm value determination of anaerobic mixed cultures were evaluated. Additionally, this SHAm assay was tested for different types of substrates and bacterial inocula. Our results demonstrate that this novel SHAm assay was a rapid, accurate and simple methodology for determining the hydrogen-producing activity of anaerobic mixed cultures. Thus, application of this approach is beneficial to establishing a stable anaerobic hydrogen-producing system.

A particle tracking method for analyzing chaotic electroosmotic flow mixing in 3D microchannels with patterned charged surfaces

NASA Astrophysics Data System (ADS)

Chang, Chih-Chang; Yang, Ruey-Jen

2006-08-01

This paper presents a numerical simulation investigation into electroosmotic flow mixing in three-dimensional microchannels with patterned non-uniform surface zeta potentials. Three types of micromixers are investigated, namely a straight diagonal strip mixer (i.e. the non-uniform surface zeta potential is applied along straight, diagonal strips on the lower wall of the mixing channel), a staggered asymmetric herringbone strip mixer and a straight diagonal/symmetric herringbone strip mixer. A particle tracing algorithm is used to visualize and evaluate the mixing performance of the various mixers. The particle trajectories and Poincaré maps of the various mixers are calculated from the three-dimensional flow fields. The surface charge patterns on the lower walls of the microchannels induce electroosmotic chaotic advection in the low Reynolds number flow regime, and hence enhance the passive mixing effect in the microfluidic devices. A quantitative measure of the mixing performance based on Shannon entropy is employed to quantify the mixing of two miscible fluids. The results show that the mixing efficiency increases as the magnitude of the heterogeneous zeta potential ratio (|ζR|) is increased, but decreases as the aspect ratio (H/W) is increased. The mixing efficiency of the straight diagonal strip mixer with a length ratio of l/W = 0.5 is slightly higher than that obtained from the same mixer with l/W = 1.0. Finally, the staggered asymmetric herringbone strip mixer with θ = 45°, ζR = -1, l/W = 0.5 and H/W = 0.2 provides the optimal mixing performance of all the mixers presented in this study.

"Hidden" O(2) and SO(2) symmetry in lepton mixing

NASA Astrophysics Data System (ADS)

Heeck, Julian; Rodejohann, Werner

2012-02-01

To generate the minimal neutrino Majorana mass matrix that has a free solar mixing angle and Δ m_{{^{text{sol}}}}^2 = 0 it suffices to implement an O(2) symmetry, or one of its subgroups SO(2), ZN ≥3, or DN ≥3. This O(2) generalizes the hidden {text{Z}}_{{^{{2}}}}^s of lepton mixing and leads in addition automatically to μ-τ symmetry. Flavor-democratic perturbations, as expected e.g. from the Planck scale, then result in tri-bimaximal mixing. We present a minimal model with three Higgs doublets implementing a type-I seesaw mechanism with a spontaneous breakdown of the symmetry, leading to large θ 13 and small Δ m_{{^{text{sol}}}}^2 = 0 due to the particular decomposition of the perturbations under μ-τ symmetry.

Clustering of Variables for Mixed Data

NASA Astrophysics Data System (ADS)

Saracco, J.; Chavent, M.

2016-05-01

This chapter presents clustering of variables which aim is to lump together strongly related variables. The proposed approach works on a mixed data set, i.e. on a data set which contains numerical variables and categorical variables. Two algorithms of clustering of variables are described: a hierarchical clustering and a k-means type clustering. A brief description of PCAmix method (that is a principal component analysis for mixed data) is provided, since the calculus of the synthetic variables summarizing the obtained clusters of variables is based on this multivariate method. Finally, the R packages ClustOfVar and PCAmixdata are illustrated on real mixed data. The PCAmix and ClustOfVar approaches are first used for dimension reduction (step 1) before applying in step 2 a standard clustering method to obtain groups of individuals.

The use of "mixing" procedure of mixed methods in health services research.

PubMed

Zhang, Wanqing; Creswell, John

2013-08-01

Mixed methods research has emerged alongside qualitative and quantitative approaches as an important tool for health services researchers. Despite growing interest, among health services researchers, in using mixed methods designs, little has been done to identify the procedural aspects of doing so. To describe how mixed methods researchers mix the qualitative and quantitative aspects of their studies in health services research. We searched the PubMed for articles, using mixed methods in health services research, published between January 1, 2006 and December 30, 2010. We identified and reviewed 30 published health services research articles on studies in which mixed methods had been used. We selected 3 articles as illustrations to help health services researcher conceptualize the type of mixing procedures that they were using. Three main "mixing" procedures have been applied within these studies: (1) the researchers analyzed the 2 types of data at the same time but separately and integrated the results during interpretation; (2) the researchers connected the qualitative and quantitative portions in phases in such a way that 1 approach was built upon the findings of the other approach; and (3) the researchers mixed the 2 data types by embedding the analysis of 1 data type within the other. "Mixing" in mixed methods is more than just the combination of 2 independent components of the quantitative and qualitative data. The use of "mixing" procedure in health services research involves the integration, connection, and embedding of these 2 data components.

Evaluation of mixed infection cases with both herpes simplex virus types 1 and 2.

PubMed

Kaneko, Hisatoshi; Kawana, Takashi; Ishioka, Ken; Ohno, Shigeaki; Aoki, Koki; Suzutani, Tatsuo

2008-05-01

Herpes simplex virus type 1 (HSV-1) is isolated principally from the upper half of the body innervated by the trigeminal ganglia whereas herpes simplex virus type 2 (HSV-2) is generally isolated from the lower half of the body innervated by the sacral ganglia. However, recent reports suggest that HSV-1 and HSV-2 can each infect both the upper and lower half of the body causing a variety of symptoms and there is a possibility that HSV-1 and HSV-2 infections can occur simultaneously with both causing symptoms. HSV type in clinical isolates from 87 patients with genital herpes and 57 with ocular herpes was determined by the polymerase chain reaction (PCR), and six cases of mixed infection with both HSV-1 and HSV-2 were identified. Of the six cases, three were patients with genital herpes and three were ocular herpes patients. Analysis of the copy number of the HSV-1 and HSV-2 genome by a quantitative real time PCR demonstrated that HSV-1 was dominant at a ratio of approximately 100:1 in the ocular infections. In contrast, the HSV-2 genome was present at a 4-40 times higher frequency in isolates from genital herpes patients. There was no obvious difference between the clinical course of mixed infection and those of single HSV-1 or HSV-2 infections. This study indicated that the frequency of mixed infection with both HSV-1 and HSV-2 is comparatively higher than those of previous reports. The genome ratio of HSV-1 and HSV-2 reflects the preference of each HSV type for the target organ.

Ecological implications of single and mixed nitrogen nutrition in Arabidopsis thaliana

PubMed Central

2013-01-01

Background Ecologists recognize that plants capture nitrogen in many chemical forms that include amino acids. Access to multiple nitrogen types in plant communities has been argued to enhance plant performance, access to nitrogen and alter ecological interactions in ways that may promote species coexistence. However, data supporting these arguments have been limited. While it is known that plants uptake amino acids from soil, long term studies that link amino acid uptake to measures of plant performance and potential reproductive effort are not typically performed. Here, a series of experiments that link uptake of nitrate, glutamine or asparagine with lifetime reproductive effort in Arabidopsis thaliana are reported. Nitrogen was offered either singly or in mixture and at a variety of combinations. Traits related to reproductive output were measured, as was the preference for each type of nitrogen. Results When plants were supplied with a single nitrogen type at concentrations from 0.1-0.9 mM, the ranking of nitrogen types was nitrate > glutamine > asparagine in terms of the relative performance of plants. When plants were supplied with two types of nitrogen in mixture at ratios between 0.1:0.9-0.9:0.1 mM, again plants performed best when nitrate was present, and poorly when amino acids were mixed. Additionally, stable isotopes revealed that plants preferentially captured nitrogen types matching the hierarchy of nitrate > glutamine > asparagine. Comparing between the two experiments revealed that mixed nitrogen nutrition was a net cost to the plants. Conclusions Plant performance on mixed nitrogen was less than half the performance on equal amounts of any single nitrogen type. We asked: why did A. thaliana capture amino acids when doing so resulted in a net cost? We argue that available data cannot yet answer this question, but hypothesize that access to lower quality forms of nitrogen may become important when plants compete. PMID:23875896

The Effects of Micromixing Two Solutions of Two Concentrations in a Two Tier PDMS Micromixer

NASA Astrophysics Data System (ADS)

Sundra, Sargunan; Fhong Soon, Chin; Zainal, Nurfarina; Sek Tee, Kian; Ahmad, Nornabihah; Gan, Siew Hua

2017-08-01

Micromixing technology has drastically advanced in the past few decades. Micromixers are one of the elements in integrated microfluidic systems for chemical, analytical chemistry, pharmaceutical, and biological applications. In this study, two tier micromixer was used to mix and dilute two solutions of similar and different concentration in order to investigate performance of micromixer’s mixing. This paper presents the fabrication of a designed micromixer using polydimethylsiloxane (PDMS) and vinyl tape methods which reduce time, cost and complexity of prototyping. The serpentine structure of the microchannels was designed to enhance both mixing and dilution. Two types of food dyes and distilled water were used to investigate the mixing performance of the micromixer followed by spectrophotometry analysis. It is observed that the single dye solution and distilled water shows better mixing performance compared to the micromixing of two dye solutions which was supported by the diffusion theory. 2.00 ml/min was the optimum flow rate that allow optimum mixing and dilution between two different concentrated liquids.

Identification of a New Spinel-Rich Lunar Rock Type by the Moon Mineralogy Mapper (M (sup 3))

NASA Technical Reports Server (NTRS)

Pieters, C. M.; Boardman, J.; Buratti, B.; Clark, R.; Combe, J. P.; Green, R.; Goswami, J. N.; Head, J. W., III; Hicks, M.; Isaacson, P.;

Scale-Up of Lubricant Mixing Process by Using V-Type Blender Based on Discrete Element Method.

PubMed

Horibe, Masashi; Sonoda, Ryoichi; Watano, Satoru

2018-01-01

A method for scale-up of a lubricant mixing process in a V-type blender was proposed. Magnesium stearate was used for the lubricant, and the lubricant mixing experiment was conducted using three scales of V-type blenders (1.45, 21 and 130 L) under the same fill level and Froude (Fr) number. However, the properties of lubricated mixtures and tablets could not correspond with the mixing time or the total revolution number. To find the optimum scale-up factor, discrete element method (DEM) simulations of three scales of V-type blender mixing were conducted, and the total travel distance of particles under the different scales was calculated. The properties of the lubricated mixture and tablets obtained from the scale-up experiment were well correlated with the mixing time determined by the total travel distance. It was found that a scale-up simulation based on the travel distance of particles is valid for the lubricant mixing scale-up processes.

Basal cell carcinoma of the skin with mixed histomorphology: a comparative study.

PubMed

Bartoš, Vladimír; Kullová, Milada

Basal cell carcinoma (BCC) of the skin exhibits a very heterogeneous histomorphology, on the basis of which it is classified into several subtypes and variants. In many cases, however, a definite categorization remains difficult, because BCC may consist of more than one histopathological subtype. There are limited data exploring the characteristics of these mixed BCCs, since they have not been specifically analysed. The aim of this study was to estimate the prevalence of BCCs with mixed histomorphology observed in a set of primary BCCs and to compare their clinicopathological features with a single type BCC subgroup. A total of 911 histologically proven primary BCCs from 697 patients were investigated. Prevalence of single and mixed type BCCs was 64.9 % and 35.1 %, respectively. In mixed type BCC subgroup, a very heterogeneous histomorphology was found comprising a mixture of two to four different subtypes in various proportions. The most frequent combinations included nodular-infiltrative, superficial-nodular, nodular-trichoepithelial and nodular-micronodular subtype. Comparative analysis of the two given subgroups showed that mixed type BCCs were significantly more frequently localized on the extrafacial regions of the head (30.0 % vs. 20.0 %, p = 0.02) and less often on the face (37.2 % vs. 45.2 %, p = 0.03). There were not convincing differences in the occurrence of single vs mixed type BCCs in other parts of the body. Histologically, mixed type BCCs exhibited an aggressive-growth pattern more frequently (64.6 % vs. 13.0 %, p < 0.0001). Positive surgical margins were significantly more common in mixed type BCC subgroup (17.8 % vs. 12.6 %, p = 0.02). Cutaneous BCCs with mixed histomorphology represented about one third of the cases. It is a common finding in routine pathological practice, probably suggestive of evolution and phenotypic transformation of the cancer. Since mixed type BCCs are frequently composed of aggressive histological subtypes, regardless the personal habits in description or terminology among pathologists, the presence of aggressive-growth component in tumor tissue should always be mentioned in final biopsy report.

Thermal-hydraulic behavior of a mixed chevron single-pass plate-and-frame heat exchanger

DOE Office of Scientific and Technical Information (OSTI.GOV)

Manglik, R.M.; Muley, A.

1995-12-31

Effective heat exchange is very critical for improving the process efficiency and operating economy of chemical and process plants. Here, experimental friction factor and heat transfer data for single-phase water flows in a plate-and-frame heat exchanger are presented. A mixed chevron plate arrangement with {beta} = 30{degree}/60{degree} in a single-pass U-type, counterflow configuration is employed. The friction factor and heat transfer data are for isothermal flow and cooling conditions, respectively, and the flow rates correspond to transition and turbulent flow regimes (300 < Re < 6,000 and 2.4 < Pr < 4.5). Based on these data, Nusselt number and frictionmore » factor correlations for fully developed turbulent flows (Re {ge} 1,000) are presented. The results highlight the effects of {beta} on the thermal-hydraulic performance, transition to turbulent flows, and the relative impact of using symmetric or mixed chevron plate arrangements.« less

Mixed-Dimensionality VLSI-Type Configurable Tools for Virtual Prototyping of Biomicrofluidic Devices and Integrated Systems

NASA Astrophysics Data System (ADS)

Makhijani, Vinod B.; Przekwas, Andrzej J.

2002-10-01

This report presents results of a DARPA/MTO Composite CAD Project aimed to develop a comprehensive microsystem CAD environment, CFD-ACE+ Multiphysics, for bio and microfluidic devices and complete microsystems. The project began in July 1998, and was a three-year team effort between CFD Research Corporation, California Institute of Technology (CalTech), University of California, Berkeley (UCB), and Tanner Research, with Mr. Don Verlee from Abbott Labs participating as a consultant on the project. The overall objective of this project was to develop, validate and demonstrate several applications of a user-configurable VLSI-type mixed-dimensionality software tool for design of biomicrofluidics devices and integrated systems. The developed tool would provide high fidelity 3-D multiphysics modeling capability, l-D fluidic circuits modeling, and SPICE interface for system level simulations, and mixed-dimensionality design. It would combine tools for layouts and process fabrication, geometric modeling, and automated grid generation, and interfaces to EDA tools (e.g. Cadence) and MCAD tools (e.g. ProE).

General Tricomi-Rassias problem and oblique derivative problem for generalized Chaplygin equations

NASA Astrophysics Data System (ADS)

Wen, Guochun; Chen, Dechang; Cheng, Xiuzhen

2007-09-01

Many authors have discussed the Tricomi problem for some second order equations of mixed type, which has important applications in gas dynamics. In particular, Bers proposed the Tricomi problem for Chaplygin equations in multiply connected domains [L. Bers, Mathematical Aspects of Subsonic and Transonic Gas Dynamics, Wiley, New York, 1958]. And Rassias proposed the exterior Tricomi problem for mixed equations in a doubly connected domain and proved the uniqueness of solutions for the problem [J.M. Rassias, Lecture Notes on Mixed Type Partial Differential Equations, World Scientific, Singapore, 1990]. In the present paper, we discuss the general Tricomi-Rassias problem for generalized Chaplygin equations. This is one general oblique derivative problem that includes the exterior Tricomi problem as a special case. We first give the representation of solutions of the general Tricomi-Rassias problem, and then prove the uniqueness and existence of solutions for the problem by a new method. In this paper, we shall also discuss another general oblique derivative problem for generalized Chaplygin equations.

Managing mixed dyslipidemia in special populations.

PubMed

Miller, Michael

2010-01-01

Controlling low-density lipoprotein cholesterol is one of the major focuses of cardiovascular care. However, the twin global pandemics of obesity and diabetes are promoting an increased prevalence of associated cardiometabolic risk factors. These factors include mixed dyslipidemia, which is prevalent among several important subgroups of the overall population. Cardiovascular risk increases as women reach and extend beyond menopause, partly reflective of dyslipidemia. In addition, women with polycystic ovary syndrome display a cluster of risk factors reminiscent of the metabolic syndrome. Certain ethnic groups are also at increased risk for type 2 diabetes or the metabolic syndrome. Dyslipidemia contributes significantly to overall cardiovascular risk in the elderly, and the frequency of children and adolescents presenting with type 2 diabetes or metabolic syndrome is increasing worldwide. Physicians should be aware of the possibility of mixed dyslipidemia in patients at elevated cardiometabolic risk. However, while combination therapy may successfully correct the associated dyslipidemia, it remains to be established whether the addition of a second agent improves coronary risk beyond statin monotherapy.

Predicting the stability of a compressible periodic parallel jet flow

NASA Technical Reports Server (NTRS)

Miles, Jeffrey H.

1996-01-01

It is known that mixing enhancement in compressible free shear layer flows with high convective Mach numbers is difficult. One design strategy to get around this is to use multiple nozzles. Extrapolating this design concept in a one dimensional manner, one arrives at an array of parallel rectangular nozzles where the smaller dimension is omega and the longer dimension, b, is taken to be infinite. In this paper, the feasibility of predicting the stability of this type of compressible periodic parallel jet flow is discussed. The problem is treated using Floquet-Bloch theory. Numerical solutions to this eigenvalue problem are presented. For the case presented, the interjet spacing, s, was selected so that s/omega =2.23. Typical plots of the eigenvalue and stability curves are presented. Results obtained for a range of convective Mach numbers from 3 to 5 show growth rates omega(sub i)=kc(sub i)/2 range from 0.25 to 0.29. These results indicate that coherent two-dimensional structures can occur without difficulty in multiple parallel periodic jet nozzles and that shear layer mixing should occur with this type of nozzle design.

The Introgression of RNAi Silencing of γ-Gliadins into Commercial Lines of Bread Wheat Changes the Mixing and Technological Properties of the Dough

PubMed Central

Gil-Humanes, Javier; Pistón, Fernando; Giménez, María J.; Martín, Antonio; Barro, Francisco

2012-01-01

In the present work the effects on dough quality by the down-regulation of γ-gliadins in different genetic backgrounds of bread wheat were investigated. RNAi-mediated silencing of γ-gliadins was introgressed by conventional crossing into three commercial bread wheat lines (namely ‘Gazul’, ‘Podenco’ and ‘Arpain’), and along with the transgenic line A1152 (cv. Bobwhite) compared with their respective wild types. The protein fractions were quantified by RP-HPLC, whereas the technological and mixing properties were assessed by SDSS test and by the Mixograph instrument. Principal component analysis (PCA) was carried out for both the wild types and the transgenic lines, showing differences in the factors affecting the technological and mixing properties of the dough as a consequence of the reduction of the γ-gliadins. In transgenic lines, the α- and ω-gliadins, and total gliadins negatively affected the dough strength and tolerance to over-mixing, whereas the L/H ratio showed the opposite effect, positively influencing the dough quality. The increase of the SDSS volume in the transgenic lines of ‘Gazul’, ‘Podenco’ and ‘Arpain’ indicates increased gluten strength and quality respect to the wild types. SDSS volume was found to be positively influenced by the amount of glutenins, which were also increased in the transgenic lines. In addition, a positive effect was observed in the MT, PR1 and RBD in some of the transgenic lines of ‘Podenco’ and ‘Arpain’. In conclusion, the down-regulation of γ-gliadins resulted in stronger doughs and a better tolerance to over-mixing in some transgenic lines. Although the reduction of γ-gliadins seems not to have a direct effect on the mixing and bread-making properties, the compensatory effect on the synthesis of the other prolamins may result in stronger doughs with improved over-mixing resistance. PMID:23029328

Monte Carlo simulation of the mixed alkali effect with cooperative jumps

NASA Astrophysics Data System (ADS)

Habasaki, Junko; Hiwatari, Yasuaki

2000-12-01

In our previous works on molecular dynamics (MD) simulations of lithium metasilicate (Li2SiO3), it has been shown that the long time behavior of the lithium ions in Li2SiO3 has been characterized by the component showing the enhanced diffusion (Lévy flight) due to cooperative jumps. It has also been confirmed that the contribution of such component decreases by interception of the paths in the mixed alkali silicate (LiKSiO3). Namely, cooperative jumps of like ions are much decreased in number owing to the interception of the path for unlike alkali-metal ions. In the present work, we have performed a Monte Carlo simulation using a cubic lattice in order to establish the role of the cooperative jumps in the transport properties in a mixed alkali glass. Fixed particles (blockage) were introduced instead of the interception of the jump paths for unlike alkali-metal ions. Two types of cooperative motions (a pull type and a push type) were taken into account. Low-dimensionality of the jump path caused by blockage resulted in a decrease of a diffusion coefficient of the particles. The effect of blockage is enhanced when the cooperative motions were introduced.

Mixed cortical adenoma and composite pheochromocytoma-ganglioneuroma: an unusual corticomedullary tumor of the adrenal gland.

PubMed

Lau, Sean K; Chu, Peiguo G; Weiss, Lawrence M

2011-06-01

Adrenal neoplasms composed of more than one cell type and demonstrating a mixed histologic appearance are exceedingly rare. We report the clinical and pathologic features of a morphologically distinctive tumor of the adrenal gland composed of cortical, chromaffin, and neural cells. Histologically, the tumor consisted of intermixed areas of proliferating cortical cells resembling adrenal cortical adenoma, neoplastic chromaffin cells consistent with pheochromocytoma, and a ganglioneuromatous stroma. The presence of the cortical, medullary, and neural components within the tumor was confirmed by immunohistochemical studies. The present case serves to broaden the morphologic spectrum of mixed tumors that may be encountered in the adrenal gland. Copyright © 2011 Elsevier Inc. All rights reserved.

Magma Mixing, Mingling and Its Accompanying Isotopic and Elemental Partitioning: Records from Titanites in Guojialing-type Granodiorites and Dioritic Enclaves, Jiaodong, North China

NASA Astrophysics Data System (ADS)

Jiang, P.; Yang, K. F.; Fan, H. R.; Liu, X.

2016-12-01

The grain-scale textural and in-situ compositional analyses on accessory minerals (such as titanite, rutile, apatite, monazite, etc.) have recently been a hot topic for geologists, through which a detailed information on magmatic, metamorphic or hydrothermal process can be extracted. As an attempt to unravel the petrogenesis of Early Cretaceous Guojialing-type granodiorites and their bearing dioritic enclaves, we accomplished an integrated geochronological and geochemical study on titanites within these rocks. Three types of titanites, with distinguishable textural and geochemical features, are identified. G-type titanites (from granodiorites) and E-type-I titanites (from plagioclase-rich dioritic enclaves) yield identical U-Pb age of 130 Ma, but reveal distinct back-scattered electron (BSE) zonings. G-type titanites are characterized by oscillatory zonings whereas E-type-I titanites are marked by core-mantle-rim zonings, exhibiting drastic but contrary variation trends for several key elements (such as LREEs, Zr, Hf and F) among their transition BSE zones. These two types of titanites are interpreted to crystallize coevally, and record a notable temperature and compositional change of two corresponding melts, as a response to magma mixing. E-type-II titanites (from plagioclase-poor dioritic enclaves) yield a relatively younger U-Pb age at 128 Ma, and show typical interstitial growth with narrower and lower range of Zr, total REEs contents, but higher F content and Nb/Ta ratios. Such titanites are perceived to record late-stage mingling, during which F-rich and REE-poor hybrid granodioritic magma squeezed into the incompletely consolidated dioritic enclaves with accompanying fluid-rock interaction. Unlike the dramatic elemental changes in these differentiated titanites, in-situ Nd isotopic compositions are relatively homogeneous, which in our view is a good sign of showing that isotopic equilibrium among two magma systems was more easily reached compared to elemental homogenization during the process of magma mixing and mingling. Our titanite work provides new and solid evidence to support a magma mixing genesis for Guojialing intrusion, and also presents a good case study of utilizing accessory titanite to decipher a detailed magmatic chamber process.

24 CFR 5.518 - Types of preservation assistance available to mixed families and other families.

Code of Federal Regulations, 2011 CFR

2011-04-01

... available to mixed families and other families. 5.518 Section 5.518 Housing and Urban Development Office of... Restrictions on Assistance to Noncitizens § 5.518 Types of preservation assistance available to mixed families and other families. (a) Continued assistance—(1) General. A mixed family may receive continued housing...

24 CFR 5.518 - Types of preservation assistance available to mixed families and other families.

Code of Federal Regulations, 2013 CFR

2013-04-01

... available to mixed families and other families. 5.518 Section 5.518 Housing and Urban Development Office of... Restrictions on Assistance to Noncitizens § 5.518 Types of preservation assistance available to mixed families and other families. (a) Continued assistance—(1) General. A mixed family may receive continued housing...

24 CFR 5.518 - Types of preservation assistance available to mixed families and other families.

Code of Federal Regulations, 2012 CFR

2012-04-01

... available to mixed families and other families. 5.518 Section 5.518 Housing and Urban Development Office of... Restrictions on Assistance to Noncitizens § 5.518 Types of preservation assistance available to mixed families and other families. (a) Continued assistance—(1) General. A mixed family may receive continued housing...

24 CFR 5.518 - Types of preservation assistance available to mixed families and other families.

Code of Federal Regulations, 2014 CFR

2014-04-01

... available to mixed families and other families. 5.518 Section 5.518 Housing and Urban Development Office of... Restrictions on Assistance to Noncitizens § 5.518 Types of preservation assistance available to mixed families and other families. (a) Continued assistance—(1) General. A mixed family may receive continued housing...

Long-lasting attentional influence of negative and taboo words in an auditory variant of the emotional Stroop task.

PubMed

Bertels, Julie; Kolinsky, Régine; Pietrons, Elise; Morais, José

2011-02-01

Using an auditory adaptation of the emotional and taboo Stroop tasks, the authors compared the effects of negative and taboo spoken words in mixed and blocked designs. Both types of words elicited carryover effects with mixed presentations and interference with blocked presentations, suggesting similar long-lasting attentional effects. Both were also relatively resilient to the long-lasting influence of the preceding emotional word. Hence, contrary to what has been assumed (Schmidt & Saari, 2007), negative and taboo words do not seem to differ in terms of the temporal dynamics of the interdimensional shifting, at least in the auditory modality. PsycINFO Database Record (c) 2011 APA, all rights reserved.

Automated mixed traffic vehicle design AMTV 2

NASA Technical Reports Server (NTRS)

Johnston, A. R.; Marks, R. A.; Cassell, P. L.

1982-01-01

The design of an improved and enclosed Automated Mixed Traffic Transit (AMTT) vehicle is described. AMTT is an innovative concept for low-speed tram-type transit in which suitable vehicles are equipped with sensors and controls to permit them to operate in an automated mode on existing road or walkway surfaces. The vehicle chassis and body design are presented in terms of sketches and photographs. The functional design of the sensing and control system is presented, and modifications which could be made to the baseline design for improved performance, in particular to incorporate a 20-mph capability, are also discussed. The vehicle system is described at the block-diagram-level of detail. Specifications and parameter values are given where available.

Ordered mixed-layer structures in the Mighei carbonaceous chondrite matrix

NASA Technical Reports Server (NTRS)

Mackinnon, I. D. R.

1982-01-01

High resolution transmission electron microscopy of the Mighei carbonaceous chondrite matrix has revealed the presence of a new mixed layer structure material. This mixed-layer material consists of an ordered arrangement of serpentine-type (S) and brucite-type (B) layers in the sequence SBBSBB. Electron diffraction and imaging techniques show that the basal periodicity is approximately 17 A. Discrete crystals of SBB-type material are typically curved, of small size (less than 1 micron) and show structural variations similar to the serpentine group minerals. Mixed-layer material also occurs in association with planar serpentine. Characteristics of SBB-type material are not consistent with known terrestrial mixed-layer clay minerals. Evidence for formation by a condensation event or by subsequent alteration of pre-existing material is not yet apparent.

Hydrogeochemistry of sodium-bicarbonate type bedrock groundwater in the Pocheon spa area, South Korea: water rock interaction and hydrologic mixing

NASA Astrophysics Data System (ADS)

Chae, Gi-Tak; Yun, Seong-Taek; Kim, Kangjoo; Mayer, Bernhard

2006-04-01

The Pocheon spa-land area, South Korea occurs in a topographically steep, fault-bounded basin and is characterized by a hydraulic upwelling flow zone of thermal water (up to 44 °C) in its central part. Hydrogeochemical and environmental isotope data for groundwater in the study area suggested the occurrence of two distinct water types, a Ca-HCO 3 type and a Na-HCO 3 type. The former water type is characterized by relatively high concentrations of Ca, SO 4 and NO 3, which show significant temporal variation indicating a strong influence by surface processes. In contrast, the Na-HCO 3 type waters have high and temporally constant temperature, pH, TDS, Na, Cl, HCO 3 and F, indicating the attainment of a chemical steady state with respect to the host rocks (granite and gneiss). Oxygen, hydrogen and tritium isotope data also indicate the differences in hydrologic conditions between the two groups: the relatively lower δ 18O, δD and tritium values for Na-HCO 3 type waters suggest that they recharged at higher elevations and have comparatively long mean residence times. Considering the geologic and hydrogeologic conditions of the study area, Na-HCO 3 type waters possibly have evolved from Ca-HCO 3 type waters. Mass balance modeling revealed that the chemistry of Na-HCO 3 type water was regulated by dissolution of silicates and carbonates and concurrent ion exchange. Particularly, low Ca concentrations in Na-HCO 3 water was mainly caused by cation exchange. Multivariate mixing and mass balance modeling (M3 modeling) was performed to evaluate the hydrologic mixing and mass transfer between discrete water masses occurring in the shallow peripheral part of the central spa-land area, where hydraulic upwelling occurs. Based on Q-mode factor analysis and mixing modeling using PHREEQC, an ideal mixing among three major water masses (surface water, shallow groundwater of Ca-HCO 3 type, deep groundwater of Na-HCO 3 type) was proposed. M3 modeling suggests that all the groundwaters in the spa area can be described as mixtures of these end-members. After mixing, the net mole transfer by geochemical reaction was less than that without mixing. Therefore, it is likely that in the hydraulic mixing zone geochemical reactions are of minor importance and, therefore, that mixing regulates the groundwater geochemistry.

7 CFR 52.1858 - Grades of mixed types or varieties of raisins.

Code of Federal Regulations, 2013 CFR

2013-01-01

... moisture, in accordance with this subpart. Mixed types of processed raisins of U.S. Grade A, U.S. Grade B, or U.S. Grade C may contain not more than 18 percent, by weight, of moisture. Mixed types of processed raisins that as a mixture exceed 18 percent, by weight, of moisture are “Substandard.” ...

7 CFR 52.1858 - Grades of mixed types or varieties of raisins.

Code of Federal Regulations, 2014 CFR

2014-01-01

... moisture, in accordance with this subpart. Mixed types of processed raisins of U.S. Grade A, U.S. Grade B, or U.S. Grade C may contain not more than 18 percent, by weight, of moisture. Mixed types of processed raisins that as a mixture exceed 18 percent, by weight, of moisture are “Substandard.” ...

Blocked versus randomized presentation modes differentially modulate feedback-related negativity and P3b amplitudes

PubMed Central

Pfabigan, Daniela M.; Zeiler, Michael; Lamm, Claus; Sailer, Uta

2014-01-01

Objective Electrophysiological studies on feedback processing typically use a wide range of feedback stimuli which might not always be comparable. The current study investigated whether two indicators of feedback processing – feedback-related negativity (FRN) and P3b – differ for feedback stimuli with explicit (facial expressions) or assigned valence information (symbols). In addition, we assessed whether presenting feedback in either a trial-by-trial or a block-wise fashion affected these ERPs. Methods EEG was recorded in three experiments while participants performed a time estimation task and received two different types of performance feedback. Results Only P3b amplitudes varied consistently in response to feedback type for both presentation types. Moreover, the blocked feedback type presentation yielded more distinct FRN peaks, higher effect sizes, and a significant relation between FRN amplitudes and behavioral task performance measures. Conclusion Both stimulus type and presentation mode may provoke systematic changes in feedback-related ERPs. The current findings point at important potential confounds that need to be controlled for when designing FRN or P3b studies. Significance Studies investigating P3b amplitudes using mixed types of stimuli have to be interpreted with caution. Furthermore, we suggest implementing a blocked presentation format when presenting different feedback types within the same experiment. PMID:24144779

Decentralized event-triggered synchronization of uncertain Markovian jumping neutral-type neural networks with mixed delays.

PubMed

Senan, Sibel; Syed Ali, M; Vadivel, R; Arik, Sabri

2017-02-01

In this study, we present an approach for the decentralized event-triggered synchronization of Markovian jumping neutral-type neural networks with mixed delays. We present a method for designing decentralized event-triggered synchronization, which only utilizes locally available information, in order to determine the time instants for transmission from sensors to a central controller. By applying a novel Lyapunov-Krasovskii functional, as well as using the reciprocal convex combination method and some inequality techniques such as Jensen's inequality, we obtain several sufficient conditions in terms of a set of linear matrix inequalities (LMIs) under which the delayed neural networks are stochastically stable in terms of the error systems. Finally, we conclude that the drive systems synchronize stochastically with the response systems. We show that the proposed stability criteria can be verified easily using the numerically efficient Matlab LMI toolbox. The effectiveness and feasibility of the results obtained are verified by numerical examples. Copyright © 2016 Elsevier Ltd. All rights reserved.

Types of Anxiety and Depression: Theoretical Assumptions and Development of the Anxiety and Depression Questionnaire

PubMed Central

Fajkowska, Małgorzata; Domaradzka, Ewa; Wytykowska, Agata

2018-01-01

The present paper is addressed to (1) the validation of a recently proposed typology of anxiety and depression, and (2) the presentation of a new tool—the Anxiety and Depression Questionnaire (ADQ)—based on this typology. Empirical data collected across two stages—construction and validation—allowed us to offer the final form of the ADQ, designed to measure arousal anxiety, apprehension anxiety, valence depression, anhedonic depression, and mixed types of anxiety and depression. The results support the proposed typology of anxiety and depression and provide evidence that the ADQ is a reliable and valid self-rating measure of affective types, and accordingly its use in scientific research is recommended. PMID:29410638

Mucinous Breast Cancer: a Review Study of 5 Year Experience from a Hospital-Based Series of Cases.

PubMed

Dumitru, Adrian; Procop, Alexandru; Iliesiu, Andreea; Tampa, Mircea; Mitrache, Luminita; Costache, Mariana; Sajin, Maria; Lazaroiu, Anca; Cirstoiu, Monica

2015-03-01

Mucinous carcinoma (also known as colloid carcinoma) is a particular type of breast cancer characterized by the presence of extracellular mucin and is linked with a more favorable prognosis than invasive breast carcinoma of no special type. Mucinous carcinoma of the breast is an uncommon form of breast tumor, often presenting as a lobulated, moderately well circumscribed mass on mammography, sonography, and MRI imaging. It accounts for 1 to 7% of all breast cancers. Pure mucinous breast carcinomas are rare and account for about 2% of all primary breast carcinomas. Metastatic disease happens at a lower rate than in other types of invasive carcinoma. We present our 5 year experience with this particular pathology in a retrospective review study. We identified 25 patients with mixed and pure mucinous breast cancer, the tumor size varied greatly from 2 to 19 cm in diameter. A subset of mixed mucinous carcinomas (8 cases) showed neuroendocrine differentiation or other associated premalignant lessions. Mucinous carcinoma of the breast is a rare entity with a favorable prognosis due to low incidence of lymph node metastases. Pure mucinous breast carcinoma has an even rare.

Mucinous Breast Cancer: a Review Study of 5 Year Experience from a Hospital-Based Series of Cases

PubMed Central

DUMITRU, Adrian; PROCOP, Alexandru; ILIESIU, Andreea; TAMPA, Mircea; MITRACHE, Luminita; COSTACHE, Mariana; SAJIN, Maria; LAZAROIU, Anca; CIRSTOIU, Monica

2015-01-01

Background: Mucinous carcinoma (also known as colloid carcinoma) is a particular type of breast cancer characterized by the presence of extracellular mucin and is linked with a more favorable prognosis than invasive breast carcinoma of no special type. Mucinous carcinoma of the breast is an uncommon form of breast tumor, often presenting as a lobulated, moderately well circumscribed mass on mammography, sonography, and MRI imaging. It accounts for 1 to 7% of all breast cancers. Pure mucinous breast carcinomas are rare and account for about 2% of all primary breast carcinomas. Metastatic disease happens at a lower rate than in other types of invasive carcinoma. Methods: We present our 5 year experience with this particular pathology in a retrospective review study. Results: We identified 25 patients with mixed and pure mucinous breast cancer, the tumor size varied greatly from 2 to 19 cm in diameter. A subset of mixed mucinous carcinomas (8 cases) showed neuroendocrine differentiation or other associated premalignant lessions. Conclusion: Mucinous carcinoma of the breast is a rare entity with a favorable prognosis due to low incidence of lymph node metastases. Pure mucinous breast carcinoma has an even rare. PMID:26225144

Metabolic consequences of resistive-type exercise

NASA Technical Reports Server (NTRS)

Dudley, G. A.

1988-01-01

This brief review concerns acute and chronic metabolic responses to resistive-type exercise (RTE) (i.e., Olympic/power weight lifting and bodybuilding). Performance of RTE presents power output substantially greater (10-15-fold) than that evident with endurance-type exercise. Accordingly, RTE relies heavily on the anaerobic enzyme machinery of skeletal muscle for energy supply, with alterations in the rate of aerobic metabolism being modest. Hydrolysis of high energy phosphate compounds (PC, ATP), glycogenolysis, and glycolysis are evident during an acute bout of RTE as indicated by metabolic markers in mixed fiber type skeletal muscle samples. The type of RTE probably influences the magnitude of these responses since the increase in blood lactate is much greater during a typical "bodybuilding" than "power lifting" session. The influence of RTE training on acute metabolic responses to RTE has received little attention. An individual's inherent metabolic characteristics are apparently sufficient to meet the energy demands of RTE as training of this type does not increase VO2max or substantially alter the content of marker enzymes in mixed fiber type skeletal muscle. Analyses of pools of fast- vs slow-twitch fibers, however, indicate that RTE-induced changes may be fiber type specific. Future studies should better delineate the metabolic responses to RTE and determine whether these are related to the enhanced performance associated with such training.

Concurrent generation of multivariate mixed data with variables of dissimilar types.

PubMed

Amatya, Anup; Demirtas, Hakan

2016-01-01

Data sets originating from wide range of research studies are composed of multiple variables that are correlated and of dissimilar types, primarily of count, binary/ordinal and continuous attributes. The present paper builds on the previous works on multivariate data generation and develops a framework for generating multivariate mixed data with a pre-specified correlation matrix. The generated data consist of components that are marginally count, binary, ordinal and continuous, where the count and continuous variables follow the generalized Poisson and normal distributions, respectively. The use of the generalized Poisson distribution provides a flexible mechanism which allows under- and over-dispersed count variables generally encountered in practice. A step-by-step algorithm is provided and its performance is evaluated using simulated and real-data scenarios.

Assembly and analysis of fragmentation data for liquid propellant vessels

NASA Technical Reports Server (NTRS)

Baker, W. E.; Parr, V. B.; Bessey, R. L.; Cox, P. A.

1974-01-01

Fragmentation data was assembled and analyzed for exploding liquid propellant vessels. These data were to be retrieved from reports of tests and accidents, including measurements or estimates of blast yield, etc. A significant amount of data was retrieved from a series of tests conducted for measurement of blast and fireball effects of liquid propellant explosions (Project PYRO), a few well-documented accident reports, and a series of tests to determine auto-ignition properties of mixing liquid propellants. The data were reduced and fitted to various statistical functions. Comparisons were made with methods of prediction for blast yield, initial fragment velocities, and fragment range. Reasonably good correlation was achieved. Methods presented in the report allow prediction of fragment patterns, given type and quantity of propellant, type of accident, and time of propellant mixing.

Radiative absorption enhancement of dust mixed with anthropogenic pollution over East Asia

NASA Astrophysics Data System (ADS)

Tian, Pengfei; Zhang, Lei; Ma, Jianmin; Tang, Kai; Xu, Lili; Wang, Yuan; Cao, Xianjie; Liang, Jiening; Ji, Yuemeng; Jiang, Jonathan H.; Yung, Yuk L.; Zhang, Renyi

2018-06-01

The particle mixing state plays a significant yet poorly quantified role in aerosol radiative forcing, especially for the mixing of dust (mineral absorbing) and anthropogenic pollution (black carbon absorbing) over East Asia. We have investigated the absorption enhancement of mixed-type aerosols over East Asia by using the Aerosol Robotic Network observations and radiative transfer model calculations. The mixed-type aerosols exhibit significantly enhanced absorbing ability than the corresponding unmixed dust and anthropogenic aerosols, as revealed in the spectral behavior of absorbing aerosol optical depth, single scattering albedo, and imaginary refractive index. The aerosol radiative efficiencies for the dust, mixed-type, and anthropogenic aerosols are -101.0, -112.9, and -98.3 Wm-2 τ-1 at the bottom of the atmosphere (BOA); -42.3, -22.5, and -39.8 Wm-2 τ-1 at the top of the atmosphere (TOA); and 58.7, 90.3, and 58.5 Wm-2 τ-1 in the atmosphere (ATM), respectively. The BOA cooling and ATM heating efficiencies of the mixed-type aerosols are significantly higher than those of the unmixed aerosol types over the East Asia region, resulting in atmospheric stabilization. In addition, the mixed-type aerosols correspond to a lower TOA cooling efficiency, indicating that the cooling effect by the corresponding individual aerosol components is partially counteracted. We conclude that the interaction between dust and anthropogenic pollution not only represents a viable aerosol formation pathway but also results in unfavorable dispersion conditions, both exacerbating the regional air pollution in East Asia. Our results highlight the necessity to accurately account for the mixing state of aerosols in atmospheric models over East Asia in order to better understand the formation mechanism for regional air pollution and to assess its impacts on human health, weather, and climate.

Using Mixed Methods and Collaboration to Evaluate an Education and Public Outreach Program (Invited)

NASA Astrophysics Data System (ADS)

Shebby, S.; Shipp, S. S.

2013-12-01

Traditional indicators (such as the number of participants or Likert-type ratings of participant perceptions) are often used to provide stakeholders with basic information about program outputs and to justify funding decisions. However, use of qualitative methods can strengthen the reliability of these data and provide stakeholders with more meaningful information about program challenges, successes, and ultimate impacts (Stern, Stame, Mayne, Forss, David & Befani, 2012). In this session, presenters will discuss how they used a mixed methods evaluation to determine the impact of an education and public outreach (EPO) program. EPO efforts were intended to foster more effective, sustainable, and efficient utilization of science discoveries and learning experiences through three main goals 1) increase engagement and support by leveraging of resources, expertise, and best practices; 2) organize a portfolio of resources for accessibility, connectivity, and strategic growth; and 3) develop an infrastructure to support coordination. The evaluation team used a mixed methods design to conduct the evaluation. Presenters will first discuss five potential benefits of mixed methods designs: triangulation of findings, development, complementarity, initiation, and value diversity (Greene, Caracelli & Graham, 2005). They will next demonstrate how a 'mix' of methods, including artifact collection, surveys, interviews, focus groups, and vignettes, was included in the EPO project's evaluation design, providing specific examples of how alignment between the program theory and the evaluation plan was best achieved with a mixed methods approach. The presentation will also include an overview of different mixed methods approaches and information about important considerations when using a mixed methods design, such as selection of data collection methods and sources, and the timing and weighting of quantitative and qualitative methods (Creswell, 2003). Ultimately, this presentation will provide insight into how a mixed methods approach was used to provide stakeholders with important information about progress toward program goals. Creswell, J.W. (2003). Research design: Qualitative, quantitative, and mixed approaches. Thousand Oaks, CA: Sage. Greene, J. C., Caracelli, V. J., & Graham, W. D. (1989). Toward a conceptual framework for mixed-method evaluation designs. Educational Evaluation and Policy Analysis, 11(3), 255-274. Stern, E; Stame, N; Mayne, J; Forss, K; Davis, R & Befani, B (2012) Broadening the range of designs and methods for impact evaluation. Department for International Development.

Conservation Laws and Ponderomotive Force for Non-WKB, MHD Waves in the Solar Wind

NASA Astrophysics Data System (ADS)

McKenzie, J. F.; Webb, G. M.; Zank, G. P.; Kaghashvili, E. K.; Ratkiewicz, R. E.

2004-12-01

The interaction of non-WKB Alfvén waves in the Solar Wind was investigated by Heinemann and Olbert (1980), MacGregor and Charbonneau (1994) and others. MacGregor and Charbonneau (1994) investigated non-WKB Alfvén wave driven winds. We discuss both the canonical and physical wave stress energy tensors for non-WKB, MHD waves and the ponderomotive force exerted by the waves on the wind for the case where both compressible (magneto-acoustic type waves) and incompressible waves (Alfvén waves) are present. The equations for the waves include the effects of wave mixing (i.e. the interaction of the waves with each other via gradients in the background flow). Wave mixing is known to be an important element of turbulence theory in the Solar Wind. However, only the wave mixing of Alfvénic type disturbances have been accounted for in present models of Solar Wind turbulence (e.g. Zhou and Matthaeus, 1990), which use Elssässer variables to describe the perturbations. The relationship between the present analysis and nearly incompressible MHD (reduced MHD) is at present unclear. Also unclear is the relationship between the present analysis and theories using wave-mean field interactions (e.g. Grimshaw (1984), Holm (1999)). The analysis is based on a theory for wave and background stress-energy tensors developed by Webb et al. (2004a,b) using a Lagrangian formulation of the total system of waves and background plasma (see e.g. Dewar (1970) for the WKB case). Conservation laws for the total system of waves and background plasma result from application of Noether's theorems relating Lie symmetries of the action to conservation laws.

7 CFR 29.3532 - Mixed (M).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Mixed (M). 29.3532 Section 29.3532 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 95) § 29.3532 Mixed (M). Variegated or distinctly different colors of the type mingled together...

7 CFR 29.3532 - Mixed (M).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed (M). 29.3532 Section 29.3532 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 95) § 29.3532 Mixed (M). Variegated or distinctly different colors of the type mingled together...

7 CFR 29.3532 - Mixed (M).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed (M). 29.3532 Section 29.3532 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 95) § 29.3532 Mixed (M). Variegated or distinctly different colors of the type mingled together...

7 CFR 29.3532 - Mixed (M).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed (M). 29.3532 Section 29.3532 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 95) § 29.3532 Mixed (M). Variegated or distinctly different colors of the type mingled together...

7 CFR 29.3532 - Mixed (M).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed (M). 29.3532 Section 29.3532 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 95) § 29.3532 Mixed (M). Variegated or distinctly different colors of the type mingled together...

A study of overflow simulations using MPAS-Ocean: Vertical grids, resolution, and viscosity

NASA Astrophysics Data System (ADS)

Reckinger, Shanon M.; Petersen, Mark R.; Reckinger, Scott J.

2015-12-01

MPAS-Ocean is used to simulate an idealized, density-driven overflow using the dynamics of overflow mixing and entrainment (DOME) setup. Numerical simulations are carried out using three of the vertical coordinate types available in MPAS-Ocean, including z-star with partial bottom cells, z-star with full cells, and sigma coordinates. The results are first benchmarked against other models, including the MITgcm's z-coordinate model and HIM's isopycnal coordinate model, which are used to set the base case used for this work. A full parameter study is presented that looks at how sensitive overflow simulations are to vertical grid type, resolution, and viscosity. Horizontal resolutions with 50 km grid cells are under-resolved and produce poor results, regardless of other parameter settings. Vertical grids ranging in thickness from 15 m to 120 m were tested. A horizontal resolution of 10 km and a vertical resolution of 60 m are sufficient to resolve the mesoscale dynamics of the DOME configuration, which mimics real-world overflow parameters. Mixing and final buoyancy are least sensitive to horizontal viscosity, but strongly sensitive to vertical viscosity. This suggests that vertical viscosity could be adjusted in overflow water formation regions to influence mixing and product water characteristics. Lastly, the study shows that sigma coordinates produce much less mixing than z-type coordinates, resulting in heavier plumes that go further down slope. Sigma coordinates are less sensitive to changes in resolution but as sensitive to vertical viscosity compared to z-coordinates.

Effects of Hydrogel Stiffness and Extracellular Compositions on Modulating Cartilage Regeneration by Mixed Populations of Stem Cells and Chondrocytes In Vivo.

PubMed

Wang, Tianyi; Lai, Janice H; Yang, Fan

2016-12-01

Cell-based therapies offer great promise for repairing cartilage. Previous strategies often involved using a single cell population such as stem cells or chondrocytes. A mixed cell population may offer an alternative strategy for cartilage regeneration while overcoming donor scarcity. We have recently reported that adipose-derived stem cells (ADSCs) can catalyze neocartilage formation by neonatal chondrocytes (NChons) when mixed co-cultured in 3D hydrogels in vitro. However, it remains unknown how the biochemical and mechanical cues of hydrogels modulate cartilage formation by mixed cell populations in vivo. The present study seeks to answer this question by co-encapsulating ADSCs and NChons in 3D hydrogels with tunable stiffness (∼1-33 kPa) and biochemical cues, and evaluating cartilage formation in vivo using a mouse subcutaneous model. Three extracellular matrix molecules were examined, including chondroitin sulfate (CS), hyaluronic acid (HA), and heparan sulfate (HS). Our results showed that the type of biochemical cue played a dominant role in modulating neocartilage deposition. CS and HA enhanced type II collagen deposition, a desirable phenotype for articular cartilage. In contrast, HS promoted fibrocartilage phenotype with the upregulation of type I collagen and failed to retain newly deposited matrix. Hydrogels with stiffnesses of ∼7-33 kPa led to a comparable degree of neocartilage formation, and a minimal initial stiffness was required to retain hydrogel integrity over time. Results from this study highlight the important role of matrix cues in directing neocartilage formation, and they offer valuable insights in guiding optimal scaffold design for cartilage regeneration by using mixed cell populations.

7 CFR 29.1035 - Mixed color (KM).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together. (See...

7 CFR 29.1035 - Mixed color (KM).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together. (See...

7 CFR 29.1035 - Mixed color (KM).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together. (See...

7 CFR 29.1035 - Mixed color (KM).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together. (See...

7 CFR 29.1035 - Mixed color (KM).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed color (KM). 29.1035 Section 29.1035 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1035 Mixed color (KM). Distinctly different colors of the type mingled together. (See...

Method for characterizing and choosing the solid mixed fuel for microthrusters of microelectromechanical systems

NASA Astrophysics Data System (ADS)

Futko, S. I.; Bondarenko, V. P.; Dolgii, L. N.

2012-05-01

We propose a method for characterizing and choosing solid mixed fuels for use as the solid-fuel charge of microthrusters of microelectromechanical systems. The method is based on the solution of the problem on the dependence of impulse responses of such a microthruster on the diameter of the outlet cross-section of its combustion chamber and the microkinetic parameters of the fuel. The variants of choosing the above fuels have been illustrated using glycidyl azide polymer/RDX as the example of a solid fuel mixture. The paper presents the characteristic criteria determining the composition of mixed fuels for the microthruster of a microelectromechanical system and considers the main types of "direct" and "inverse" problems arising in characterizing and choosing such fuels.

Evolution and Nucleosynthesis of Massive Stars

NASA Astrophysics Data System (ADS)

Meynet, Georges; Maeder, André; Choplin, Arthur; Takahashi, Koh; Ekström, Sylvia; Hirschi, Raphael; Chiappini, Cristina; Eggenberger, Patrick

Massive stars are rapid nuclear reactors that play a key role in injecting new synthesized elements in the interstellar medium. Depending on the strengths of the stellar winds on the efficiency of mixing processes, the masses and the chemical compositions of their ejecta can be dramatically different. In a first part, we describe two types of rotating models differing by the physics involved and discussing various consequences. In a second part, we focus on the impacts of rotation in massive stars at very low metallicity. Various nucleosynthetic signatures pointing towards the need for some extra-mixing in the first generation of stars are presented. This extra-mixing has great chance to be driven by rotation for the following reasons: 1) when the metallicity decreases, the formation of fast rotators seem to be favored; 2) rotational mixing is more efficient at low metallicities; 3) primary nitrogen is produced only at low metallicities a fact that can be well explained by more efficient rotational mixing at low metallicities.

Theoretical analysis of mixing in liquid clouds – Part 3: Inhomogeneous mixing

DOE PAGES

Pinsky, Mark; Khain, Alexander; Korolev, Alexei

2016-07-28

An idealized diffusion–evaporation model of time-dependent mixing between a cloud volume and a droplet-free volume is analyzed. The initial droplet size distribution (DSD) in the cloud volume is assumed to be monodisperse. It is shown that evolution of the microphysical variables and the final equilibrium state are unambiguously determined by two non-dimensional parameters. The first one is the potential evaporation parameter R, proportional to the ratio of the saturation deficit to the liquid water content in the cloud volume, that determines whether the equilibrium state is reached at 100 % relative humidity, or is characterized by a complete evaporation ofmore » cloud droplets. The second parameter Da is the Damkölher number equal to the ratio of the characteristic mixing time to the phase relaxation time. Parameters R and Da determine the type of mixing. The results are analyzed within a wide range of values of R and Da. It is shown that there is no pure homogeneous mixing, since the first mixing stage is always inhomogeneous. The mixing type can change during the mixing process. Any mixing type leads to formation of a tail of small droplets in DSD and, therefore, to DSD broadening that depends on Da. At large Da, the final DSD dispersion can be as large as 0.2. The total duration of mixing varies from several to 100 phase relaxation time periods, depending on R and Da. The definitions of homogeneous and inhomogeneous types of mixing are reconsidered and clarified, enabling a more precise delimitation between them. The paper also compares the results obtained with those based on the classic mixing concepts.« less

Theoretical analysis of mixing in liquid clouds – Part 3: Inhomogeneous mixing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pinsky, Mark; Khain, Alexander; Korolev, Alexei

An idealized diffusion–evaporation model of time-dependent mixing between a cloud volume and a droplet-free volume is analyzed. The initial droplet size distribution (DSD) in the cloud volume is assumed to be monodisperse. It is shown that evolution of the microphysical variables and the final equilibrium state are unambiguously determined by two non-dimensional parameters. The first one is the potential evaporation parameter R, proportional to the ratio of the saturation deficit to the liquid water content in the cloud volume, that determines whether the equilibrium state is reached at 100 % relative humidity, or is characterized by a complete evaporation ofmore » cloud droplets. The second parameter Da is the Damkölher number equal to the ratio of the characteristic mixing time to the phase relaxation time. Parameters R and Da determine the type of mixing. The results are analyzed within a wide range of values of R and Da. It is shown that there is no pure homogeneous mixing, since the first mixing stage is always inhomogeneous. The mixing type can change during the mixing process. Any mixing type leads to formation of a tail of small droplets in DSD and, therefore, to DSD broadening that depends on Da. At large Da, the final DSD dispersion can be as large as 0.2. The total duration of mixing varies from several to 100 phase relaxation time periods, depending on R and Da. The definitions of homogeneous and inhomogeneous types of mixing are reconsidered and clarified, enabling a more precise delimitation between them. The paper also compares the results obtained with those based on the classic mixing concepts.« less

Towards Time-Scaling of Mixing for the Campanian Ignimbrite: Systemic Variation in Sr-Isotopic Composition from Mixing Experiments

NASA Astrophysics Data System (ADS)

de Campos, Cristina; Civetta, Lucia; Perugini, Diego; Dingwell, Donald B.

2010-05-01

Eruptions in the Campi Flegrei caldera, the most dangerous volcanic setting in Europe, are thought to be triggered by short-term pre-eruptive mixing of trachytic to trachydacitic resident and new basaltic, trachyandesitic (=shoshonitic) magma, in shallow magma chambers (e. g. Arienzo et al, 2008, Bull. Volcanol.). Previous geochemical and volcanological data on the Campanian Ignimbrite, (>150 km3, 39 Ma), in Campi Flegrei, point towards a layered reservoir, which evolved from the replenishment of the magma chamber with shoshonitic magma and short-term pre-eruptive mixing between a trachytic and a phonolitic trachytic magma. With the purpose to experimentally study the mobility and homogenization of Rb-Sr isotopes in this system, we performed mixing experiments using natural phonolitic trachytic (end-member A - S. Nicola type) and trachytic (end-member B - Mondragone-type) samples, representing the two end-members involved in the origin of the Campanian Ignimbrite. Resultant glasses from a time series, ranging from 1-hour up to 1-week, under constant flow velocity (0.5 rotations per minute; after De Campos et al., 2008. Chem. Geol.), have been analysed with respect to the Rb- and Sr-systematics. Our results reveal a progressive homogenization of the contrasting Sr-isotopes towards a hybrid value. With increasing experimental duration a clear decrease in the standard deviation of isotopic ratios has been observed, reflecting progressive isotopic homogenization. Our results also support the effectiveness of mixing in the Campi Flegrei reservoirs, in liquidus, under high temperature, before the onset of fractional crystallization. Since different eruptive events from Campi Flegrei can be well characterized by means of isotopic composition, the main goal for the present study will be to use experimental data and numerical modeling in order to estimate time scales of mixing associated with the eruption of the Campanian Ignimbrite, and then compare them to the several other volcanic events in Campi Flegrei. The results to be presented will be corrected according to the recently developed numerical modeling by Perugini et al. (in print, Bull. Volcanol.).

Divided spatial attention and feature-mixing errors.

PubMed

Golomb, Julie D

2015-11-01

Spatial attention is thought to play a critical role in feature binding. However, often multiple objects or locations are of interest in our environment, and we need to shift or split attention between them. Recent evidence has demonstrated that shifting and splitting spatial attention results in different types of feature-binding errors. In particular, when two locations are simultaneously sharing attentional resources, subjects are susceptible to feature-mixing errors; that is, they tend to report a color that is a subtle blend of the target color and the color at the other attended location. The present study was designed to test whether these feature-mixing errors are influenced by target-distractor similarity. Subjects were cued to split attention across two different spatial locations, and were subsequently presented with an array of colored stimuli, followed by a postcue indicating which color to report. Target-distractor similarity was manipulated by varying the distance in color space between the two attended stimuli. Probabilistic modeling in all cases revealed shifts in the response distribution consistent with feature-mixing errors; however, the patterns differed considerably across target-distractor color distances. With large differences in color, the findings replicated the mixing result, but with small color differences, repulsion was instead observed, with the reported target color shifted away from the other attended color.

Numerical study on the mixing performance of a ring-type electroosmotic micromixer with different obstacle configurations.

PubMed

Seo, Hyeon-Seok; Han, Bongtae; Kim, Youn-Jea

2012-06-01

A new type of electrokinetic micromixer with a ring-type channel is introduced for fast mixing. The proposed mixer takes two fluids from different inlets and combines them in a ring-type mixing chamber. The fluids enter two different inlets (inner radius: 25 microm and outer radius: 50 microm), respectively. The total channel length is 500 microm, and four microelectrodes are positioned on the outer wall of the mixing chamber. The electric potentials on the four microelectrodes are sinusoidal with time, having various maximum values of voltage, zeta potential and frequency. Also, in order to compare the mixing performance with different obstacle configurations, we performed a numerical analysis using a commercial code, COMSOL. The concentration of the dissolved substances in the working fluid and the flow and electric fields in the channel were investigated and the results were graphically depicted for various flow and electric conditions.

Physiological effects of diet mixing on consumer fitness: a meta-analysis.

PubMed

Lefcheck, Jonathan S; Whalen, Matthew A; Davenport, Theresa M; Stone, Joshua P; Duffy, J Emmett

2013-03-01

The degree of dietary generalism among consumers has important consequences for population, community, and ecosystem processes, yet the effects on consumer fitness of mixing food types have not been examined comprehensively. We conducted a meta-analysis of 161 peer-reviewed studies reporting 493 experimental manipulations of prey diversity to test whether diet mixing enhances consumer fitness based on the intrinsic nutritional quality of foods and consumer physiology. Averaged across studies, mixed diets conferred significantly higher fitness than the average of single-species diets, but not the best single prey species. More than half of individual experiments, however, showed maximal growth and reproduction on mixed diets, consistent with the predicted benefits of a balanced diet. Mixed diets including chemically defended prey were no better than the average prey type, opposing the prediction that a diverse diet dilutes toxins. Finally, mixed-model analysis showed that the effect of diet mixing was stronger for herbivores than for higher trophic levels. The generally weak evidence for the nutritional benefits of diet mixing in these primarily laboratory experiments suggests that diet generalism is not strongly favored by the inherent physiological benefits of mixing food types, but is more likely driven by ecological and environmental influences on consumer foraging.

Oil mixing behavior after an oil spill: identification conflicts of different fingerprints.

PubMed

He, Shijie; Yu, Hongjun; Luo, Yongming; Wang, Chuanyuan; Li, Xueshuang; Li, Zhongping

2018-04-01

Clearing up whether spilled oil is mixed or not can strengthen the accuracy of oil spill identification. In the present study, the biomarkers in spilled oil samples were detected. The weathering modes of different types of diagnostic ratio and carbon isotope values of individual n-alkanes were also analyzed. The results showed that the diagnostic ratios of steroids, terpenes and aromatics, and weathering characteristics of carbon isotope composition (δ 13 C) of individual n-alkanes supported the idea that Dalian oil spill emerged from a single oil source. Furthermore, commonly used diagnostic ratios of n-alkanes indicated that the Dalian oil spill had undergone the oil mixing process. The different identifying outcomes indicate that some kinds of n-alkane-rich substance (such as oil dispersants) were mixed in the Dalian spilled oil and interfered with the routine diagnosis ratios of n-alkanes.

Financial Performance of Mixed-Age Naturally Regenerated Loblolly-Hardwood Stands in the South Central United States

Treesearch

Ronald Raunikar; Joseph Buongiorno; Jeffrey P. Prestemon; Karen Lee Abt

2000-01-01

To estimate the financial performance of a natural mixed species and mixed-age management in the loblolly-pine forest type, we examined 991 FIA plots in the south central states. The plots were of the loblolly pine forest type, mixed-age, and had been regenerated naturally. We gauged the financial performance of each plot from the equivalent annual income (EAI)...

Impact of grazing abandonment on floristic diversity in the priority habitat type *9562 Grecian Juniper Woods

NASA Astrophysics Data System (ADS)

Vrahnakis, Michael; Kazoglou, Yannis; Fotiadis, George; Kakouros, Petros; Nasiakou, Stamatia; Soutsas, Konstantinos

2017-04-01

The habitat type *9562 Grecian juniper woods (Juniperetum excelsae) includes Greek juniper (Juniperus excelsa M. Bieb.) forests and they are found mainly in the western sector of the Prespa National Park, NW Greece. Greek juniper forests are considered extremely rare for EU-28, recommending a priority habitat type in accordance with Directive 92/43/EEC. In addition, their ecological importance is great given its high plant taxa richness; they harbor most of the 900 plant taxa found in the western sector of the Park, many of them being important for EU or global scale. The accelerated invasion of deciduous hardwoods is the most significant risk for the habitat, since its rich flora is well-adapted to open light conditions produced by the open spaced Greek junipers. Also, the dense vegetated conditions deprive the regeneration of the photophilous Greek juniper. The invasion results from the lack of its natural controller, i.e. the grazing livestock. It is estimated that the total area of juniper forests for the Devas area decreased to 89% of the area of 1945 in favor of invasive hardwoods. The paper presents the analysis of the floristic diversity of the priority habitat type *9562 Grecian Juniper Woods (Juniperetum excelsae) (GJWs). Four (4) types of juniper forest ranges (GJWs) were distinguished in terms of canopy cover: (a) pure GJWs, (b) mixed open GJWs, (c) open GJWs, and (d) mixed dense GJWs. A total of 171 plant taxa were recorded, and distributed within 43 botanical families; the largest one being Leguminosae (26 taxa). The statistically estimated plant taxa richness for pure GJWs was 116.4, for mixed open 152.6, for open 57.9, and for mixed dense 90.2 taxa. The analysis of α-diversity indices did not reveal any specific trend of diversity for the four GJWs. The behavior of the variability of diversity among the four range types of GJWs was depending on the emphasis the used indices place on properties such as taxa richness or abundance. This fact was reflected in the diversity ordering diagram, based on the Renyi's index; it was shown that the response system of the four GJWs appeared as dynamic and thus reflected the distance of a standard system and a distinct floristic diversity regime of four levels. However it seems that mixed dense GJWs had the lowest floristic diversity, while the largest had the pure and mixed open GJWs.

Mixed ternary heterojunction solar cell

DOEpatents

Chen, Wen S.; Stewart, John M.

1992-08-25

A thin film heterojunction solar cell and a method of making it has a p-type layer of mixed ternary I-III-VI.sub.2 semiconductor material in contact with an n-type layer of mixed binary II-VI semiconductor material. The p-type semiconductor material includes a low resistivity copper-rich region adjacent the back metal contact of the cell and a composition gradient providing a minority carrier mirror that improves the photovoltaic performance of the cell. The p-type semiconductor material preferably is CuInGaSe.sub.2 or CuIn(SSe).sub.2.

Blocked versus randomized presentation modes differentially modulate feedback-related negativity and P3b amplitudes.

PubMed

Pfabigan, Daniela M; Zeiler, Michael; Lamm, Claus; Sailer, Uta

2014-04-01

Electrophysiological studies on feedback processing typically use a wide range of feedback stimuli which might not always be comparable. The current study investigated whether two indicators of feedback processing - feedback-related negativity (FRN) and P3b - differ for feedback stimuli with explicit (facial expressions) or assigned valence information (symbols). In addition, we assessed whether presenting feedback in either a trial-by-trial or a block-wise fashion affected these ERPs. EEG was recorded in three experiments while participants performed a time estimation task and received two different types of performance feedback. Only P3b amplitudes varied consistently in response to feedback type for both presentation types. Moreover, the blocked feedback type presentation yielded more distinct FRN peaks, higher effect sizes, and a significant relation between FRN amplitudes and behavioral task performance measures. Both stimulus type and presentation mode may provoke systematic changes in feedback-related ERPs. The current findings point at important potential confounds that need to be controlled for when designing FRN or P3b studies. Studies investigating P3b amplitudes using mixed types of stimuli have to be interpreted with caution. Furthermore, we suggest implementing a blocked presentation format when presenting different feedback types within the same experiment. Copyright © 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

YAG laser in the treatment of hemorrhoids: a report of 700 cases

NASA Astrophysics Data System (ADS)

Liu, Jian-xun; Zhang, Xinrong

1993-03-01

The results of treating hemorrhoids in 700 cases with a YAG laser knife is reported. Since 1988, the author introduced the YAG laser into the treatment of various kinds of hemorrhoids. The satisfactory results were achieved with 100% cure rate. Some related problems also are discussed in this paper. Hemorrhoid is a kind of common disease. It usually appears in the superior or inferior rectal venous plexus covered with mucosa. The hemorrhoids are divided into internal, external, and mixed types according to their location and origination. The internal hemorrhoid is superior to the dentate line and caused by varicosity of superior rectal venous plexus covered with mucosa, the most common presentation is a bleeding and prolapse mass out of the anus. The external hemorrhoid arises from varicosity of inferior rectal venous plexus, the most important clinical finding is a painful mass covered with skin of the anal canal. The characteristics of mixed type are the combination of the two types as mentioned above.

Victimisation through bullying and cyberbullying: Emotional intelligence, severity of victimisation and technology use in different types of victims.

PubMed

Beltrán-Catalán, María; Zych, Izabela; Ortega-Ruiz, Rosario; Llorent, Vicente J

2018-05-01

Bullying and cyberbullying are global public health problems. However, very few studies described prevalence, similarities and differences among face-to-face victims, cybervictims and students who are victimised through both bullying and cyberbullying. This study was conducted to describe these different patterns of victimisation and severity of victimisation, emotional intelligence and technology use in different types of victims. A total number of 2,139 secondary school students from 22 schools, randomly selected from all provinces of Andalusia, Spain, participated in this study. Information about bullying, cyberbullying, social networking sites use and perceived emotional intelligence was collected. Face-to-face victimisation only is the most common type of victimisation followed by mixed victimisation. Cybervictimisation only is rare. Mixed victims score higher in severity of bullying and present higher emotional attention than face-to-face victims. Most victims of cyberbullying are also face-to-face victims. Holistic approach that focuses on different problems at the same time seems to be needed to tackle these behaviours.

Influence of nano-material on the expansive and shrinkage soil behavior

NASA Astrophysics Data System (ADS)

Taha, Mohd Raihan; Taha, Omer Muhie Eldeen

2012-10-01

This paper presents an experimental study performed on four types of soils mixed with three types of nano-material of different percentages. The expansion and shrinkage tests were conducted to investigate the effect of three type of nano-materials (nano-clay, nano-alumina, and nano-copper) additive on repressing strains in compacted residual soil mixed with different ratios of bentonite (S1 = 0 % bentonite, S2 = 5 % bentonite, S3 = 10 % bentonite, and S4 = 20 % bentonite). The soil specimens were compacted under the condition of maximum dry unit weight and optimum water content ( w opt) using standard compaction test. The physical and mechanical results of the treated samples were determined. The untreated soil values were used as control points for comparison purposes. It was found that with the addition of optimum percentage of nano-material, both the swell strain and shrinkage strain reduced. The results show that nano-material decreases the development of desiccation cracks on the surface of compacted samples without decrease in the hydraulic conductivity.

Regression analysis of mixed recurrent-event and panel-count data

PubMed Central

Zhu, Liang; Tong, Xinwei; Sun, Jianguo; Chen, Manhua; Srivastava, Deo Kumar; Leisenring, Wendy; Robison, Leslie L.

2014-01-01

In event history studies concerning recurrent events, two types of data have been extensively discussed. One is recurrent-event data (Cook and Lawless, 2007. The Analysis of Recurrent Event Data. New York: Springer), and the other is panel-count data (Zhao and others, 2010. Nonparametric inference based on panel-count data. Test 20, 1–42). In the former case, all study subjects are monitored continuously; thus, complete information is available for the underlying recurrent-event processes of interest. In the latter case, study subjects are monitored periodically; thus, only incomplete information is available for the processes of interest. In reality, however, a third type of data could occur in which some study subjects are monitored continuously, but others are monitored periodically. When this occurs, we have mixed recurrent-event and panel-count data. This paper discusses regression analysis of such mixed data and presents two estimation procedures for the problem. One is a maximum likelihood estimation procedure, and the other is an estimating equation procedure. The asymptotic properties of both resulting estimators of regression parameters are established. Also, the methods are applied to a set of mixed recurrent-event and panel-count data that arose from a Childhood Cancer Survivor Study and motivated this investigation. PMID:24648408

A multi-objective genetic algorithm for a mixed-model assembly U-line balancing type-I problem considering human-related issues, training, and learning

NASA Astrophysics Data System (ADS)

Rabbani, Masoud; Montazeri, Mona; Farrokhi-Asl, Hamed; Rafiei, Hamed

2016-12-01

Mixed-model assembly lines are increasingly accepted in many industrial environments to meet the growing trend of greater product variability, diversification of customer demands, and shorter life cycles. In this research, a new mathematical model is presented considering balancing a mixed-model U-line and human-related issues, simultaneously. The objective function consists of two separate components. The first part of the objective function is related to balance problem. In this part, objective functions are minimizing the cycle time, minimizing the number of workstations, and maximizing the line efficiencies. The second part is related to human issues and consists of hiring cost, firing cost, training cost, and salary. To solve the presented model, two well-known multi-objective evolutionary algorithms, namely non-dominated sorting genetic algorithm and multi-objective particle swarm optimization, have been used. A simple solution representation is provided in this paper to encode the solutions. Finally, the computational results are compared and analyzed.

Visualized analysis of mixed numeric and categorical data via extended self-organizing map.

PubMed

Hsu, Chung-Chian; Lin, Shu-Han

2012-01-01

Many real-world datasets are of mixed types, having numeric and categorical attributes. Even though difficult, analyzing mixed-type datasets is important. In this paper, we propose an extended self-organizing map (SOM), called MixSOM, which utilizes a data structure distance hierarchy to facilitate the handling of numeric and categorical values in a direct, unified manner. Moreover, the extended model regularizes the prototype distance between neighboring neurons in proportion to their map distance so that structures of the clusters can be portrayed better on the map. Extensive experiments on several synthetic and real-world datasets are conducted to demonstrate the capability of the model and to compare MixSOM with several existing models including Kohonen's SOM, the generalized SOM and visualization-induced SOM. The results show that MixSOM is superior to the other models in reflecting the structure of the mixed-type data and facilitates further analysis of the data such as exploration at various levels of granularity.

Site-level progression of periodontal disease during a follow-up period

PubMed Central

Morozumi, Toshiya; Nakagawa, Taneaki; Sugaya, Tsutomu; Kawanami, Masamitsu; Suzuki, Fumihiko; Takahashi, Keiso; Abe, Yuzo; Sato, Soh; Makino-Oi, Asako; Saito, Atsushi; Takano, Satomi; Minabe, Masato; Nakayama, Yohei; Ogata, Yorimasa; Kobayashi, Hiroaki; Izumi, Yuichi; Sugano, Naoyuki; Ito, Koichi; Sekino, Satoshi; Numabe, Yukihiro; Fukaya, Chie; Yoshinari, Nobuo; Fukuda, Mitsuo; Noguchi, Toshihide; Kono, Tomoo; Umeda, Makoto; Fujise, Osamu; Nishimura, Fusanori; Yoshimura, Atsutoshi; Hara, Yoshitaka; Nakamura, Toshiaki; Noguchi, Kazuyuki; Kakuta, Erika; Hanada, Nobuhiro; Takashiba, Shogo; Amitani, Yasuharu; Yoshie, Hiromasa

2017-01-01

Periodontal disease is assessed and its progression is determined via observations on a site-by-site basis. Periodontal data are complex and structured in multiple levels; thus, applying a summary statistical approach (i.e., the mean) for site-level evaluations results in loss of information. Previous studies have shown the availability of mixed effects modeling. However, clinically beneficial information on the progression of periodontal disease during the follow-up period is not available. We conducted a multicenter prospective cohort study. Using mixed effects modeling, we analyzed 18,834 sites distributed on 3,139 teeth in 124 patients, and data were collected 5 times over a 24-month follow-up period. The change in the clinical attachment level (CAL) was used as the outcome variable. The CAL at baseline was an important determinant of the CAL changes, which varied widely according to the tooth surface. The salivary levels of periodontal pathogens, such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, were affected by CAL progression. “Linear”- and “burst”-type patterns of CAL progression occurred simultaneously within the same patient. More than half of the teeth that presented burst-type progression sites also presented linear-type progression sites, and most of the progressions were of the linear type. Maxillary premolars and anterior teeth tended to show burst-type progression. The parameters identified in this study may guide practitioners in determining the type and extent of treatment needed at the site and patient levels. In addition, these results show that prior hypotheses concerning "burst" and "linear" theories are not valid. PMID:29206238

Four-Wave-Mixing Oscillations in a simplified Boltzmannian semiconductor model with LO-phonons

NASA Astrophysics Data System (ADS)

Tamborenea, P. I.; Bányai, L.; Haug, H.

1996-03-01

The recently discovered(L. Bányai, D. B. Tran Thoai, E. Reitsamer, H. Haug, D. Steinbach, M. U. Wehner, M. Wegener, T. Marschner and W. Stolz, Phys. Rev. Lett. 75), 2188 (1995). oscillations of the integrated four-wave-mixing signal in semiconductors due to electron-LO-phonon scattering are studied within a simplified Boltzmann-type model. Although several aspects of the experimental results require a description within the framework of non-Markovian quantum-kinetic theory, our simplified Boltzmannian model is well suited to analyze the origin of the observed novel oscillations of frequency (1+m_e/m_h) hbarω_LO. To this end, we developed a third-order, analytic solution of the semiconductor Bloch equations (SBE) with Boltzmann-type, LO-phonon collision terms. Results of this theory along with numerical solutions of the SBE will be presented.

The resonance of twin supersonic jets

NASA Technical Reports Server (NTRS)

Morris, Philip J.

1989-01-01

This paper presents an analytical study of the resonant interaction between twin supersonic jets. An instability wave model is used to describe the large scale coherent structures in the jet mixing layers. A linearized shock cell model is also given for the jets when operating off design. The problem's geometry admits four types of normal modes associated with each azimuthal mode number in the single jet. The stability of these modes is examined for both a vortex sheet model of the jet and a jet flow represented by realistic profiles. The growth rates of each mode number and type are found to vary with jet separation and mixing layer thickness and Strouhal number. Contours of equal pressure level are obtained for each mode. The region close to the symmetry axis is found to have the greatest pressure fluctuation amplitude.

7 CFR 29.2534 - Mixed color or variegated (M).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed color or variegated (M). 29.2534 Section 29.2534 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Foreign-Grown Fire-Cured Tobacco (u.s. Types 22, 23, and Foreign Type 96) § 29.2534 Mixed color or...

7 CFR 29.2534 - Mixed color or variegated (M).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed color or variegated (M). 29.2534 Section 29.2534 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Foreign-Grown Fire-Cured Tobacco (u.s. Types 22, 23, and Foreign Type 96) § 29.2534 Mixed color or...

7 CFR 29.2534 - Mixed color or variegated (M).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed color or variegated (M). 29.2534 Section 29.2534 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... Foreign-Grown Fire-Cured Tobacco (u.s. Types 22, 23, and Foreign Type 96) § 29.2534 Mixed color or...

21 CFR 226.102 - Master-formula and batch-production records.

Code of Federal Regulations, 2010 CFR

2010-04-01

...(s) produced on a batch or continuous operation basis, including mixing steps and mixing times that have been determined to yield an adequately mixed Type A medicated article(s); and in the case of Type... batch size, or of appropriate size in the case of continuous systems to be produced from the master...

Mixed methods research in mental health nursing.

PubMed

Kettles, A M; Creswell, J W; Zhang, W

2011-08-01

Mixed methods research is becoming more widely used in order to answer research questions and to investigate research problems in mental health and psychiatric nursing. However, two separate literature searches, one in Scotland and one in the USA, revealed that few mental health nursing studies identified mixed methods research in their titles. Many studies used the term 'embedded' but few studies identified in the literature were mixed methods embedded studies. The history, philosophical underpinnings, definition, types of mixed methods research and associated pragmatism are discussed, as well as the need for mixed methods research. Examples of mental health nursing mixed methods research are used to illustrate the different types of mixed methods: convergent parallel, embedded, explanatory and exploratory in their sequential and concurrent combinations. Implementing mixed methods research is also discussed briefly and the problem of identifying mixed methods research in mental and psychiatric nursing are discussed with some possible solutions to the problem proposed. © 2011 Blackwell Publishing.

Using mixed methods in health research

PubMed Central

Woodman, Jenny

2013-01-01

Summary Mixed methods research is the use of quantitative and qualitative methods in a single study or series of studies. It is an emergent methodology which is increasingly used by health researchers, especially within health services research. There is a growing literature on the theory, design and critical appraisal of mixed methods research. However, there are few papers that summarize this methodological approach for health practitioners who wish to conduct or critically engage with mixed methods studies. The objective of this paper is to provide an accessible introduction to mixed methods for clinicians and researchers unfamiliar with this approach. We present a synthesis of key methodological literature on mixed methods research, with examples from our own work and that of others, to illustrate the practical applications of this approach within health research. We summarize definitions of mixed methods research, the value of this approach, key aspects of study design and analysis, and discuss the potential challenges of combining quantitative and qualitative methods and data. One of the key challenges within mixed methods research is the successful integration of quantitative and qualitative data during analysis and interpretation. However, the integration of different types of data can generate insights into a research question, resulting in enriched understanding of complex health research problems. PMID:23885291

Differences in body dissatisfaction, weight-management practices and food choices of high-school students in the Bangkok metropolitan region by gender and school type.

PubMed

Chongwatpol, Pitipa; Gates, Gail E

2016-05-01

The present study aimed to compare body dissatisfaction, food choices, physical activity and weight-management practices by gender and school type. A questionnaire was used to obtain height, weight, body image perception using Stunkard's figure rating scale, food choices, physical activity and weight-management practices. Nine single- and mixed-gender schools located in Bangkok Metropolitan Region, Thailand. Students in 10th-12th grade, aged 15-18 years (n 2082). Only 18% of females and 21% of males did not indicate body dissatisfaction. About 66% of females selected a thinner ideal figure than their current figure. Among males, 44% wanted a thinner figure, but 35% wanted a bigger figure. However, univariate analysis found differences by school type but not gender in the degree of body dissatisfaction; students in single-gender schools had more body dissatisfaction. Females reported using more weight-management practices but less physical activity, while males reported healthier food choices. Participants in single-gender schools had healthier food choices compared with those in mixed-gender schools. Adolescents who were at increased risk of a greater degree of body dissatisfaction were females, attended single-gender schools, had lower household income, higher BMI and less physical activity. Most participants reported being dissatisfied with their current body shape, but the type and level of dissatisfaction and use of weight-management practices differed by gender and type of school. These findings suggest that programmes to combat body dissatisfaction should address different risk factors in males and females attending single- and mixed-gender schools.

Single axis controlled hybrid magnetic bearing for left ventricular assist device: hybrid core and closed magnetic circuit.

PubMed

da Silva, Isaias; Horikawa, Oswaldo; Cardoso, Jose R; Camargo, Fernando A; Andrade, Aron J P; Bock, Eduardo G P

2011-05-01

In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in which the active control is executed in only one degree of freedom, in the axial direction of the rotor. Remaining degrees of freedom, excepting the rotation, are restricted only by the attraction force between pairs of permanent magnets. This study is part of a joint project in development by IDPC and Escola Politecnica of São Paulo University, Brazil. This article shows advances in that project, presenting two promising solutions for magnetic bearings. One solution uses hybrid cores as electromagnetic actuators, that is, cores that combine iron and permanent magnets. The other solution uses actuators, also of hybrid type, but with the magnetic circuit closed by an iron core. After preliminary analysis, a pump prototype has been developed for each solution and has been tested. For each prototype, a brushless DC motor has been developed as the rotor driver. Each solution was evaluated by in vitro experiments and guidelines are extracted for future improvements. Tests have shown good results and demonstrated that one solution is not isolated from the other. One complements the other for the development of a single-axis-controlled, hybrid-type magnetic bearing for a mixed-flow type VAD. © 2011, Copyright the Authors. Artificial Organs © 2011, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Effect of Noise on the Relaxation to an Invariant Probability Measure of Nonhyperbolic Chaotic Attractors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anishchenko, Vadim S.; Vadivasova, Tatjana E.; Kopeikin, Andrey S.

2001-07-30

We study the influence of external noise on the relaxation to an invariant probability measure for two types of nonhyperbolic chaotic attractors, a spiral (or coherent) and a noncoherent one. We find that for the coherent attractor the rate of mixing changes under the influence of noise, although the largest Lyapunov exponent remains almost unchanged. A mechanism of the noise influence on mixing is presented which is associated with the dynamics of the instantaneous phase of chaotic trajectories. This also explains why the noncoherent regime is robust against the presence of external noise.

Effect of electrode positions on the mixing characteristics of an electroosmotic micromixer.

PubMed

Seo, H S; Kim, Y J

2014-08-01

In this study, an electrokinetic microchannel with a ring-type mixing chamber is introduced for fast mixing. The modeled micromixer that is used for the study of the electroosmotic effect takes two fluids from different inlets and combines them in a ring-type mixing chamber and, then, they are mixed by the electric fields at the electrodes. In order to compare the mixing performance in the modeled micromixer, we numerically investigated the flow characteristics with different positions of the electrodes in the mixing chamber using the commercial code, COMSOL. In addition, we discussed the concentration distributions of the dissolved substances in the flow fields and compared the mixing efficiency in the modeled micromixer with different electrode positions and operating conditions, such as the frequencies and electric potentials at the electrodes.

Features of Red Sea Water Masses

NASA Astrophysics Data System (ADS)

Kartadikaria, Aditya; Hoteit, Ibrahim

2015-04-01

Features of Red Sea water mass can be divided into three types but best to be grouped into two different classes that are split at the potential density line σθ=27.4. The surface water (0-50 m) and the intermediate water (50-200 m) have nearly identical types of water mass. They appear as a maxima salinity layer for the water mass that has σθ > 26.0, and as a minimum salinity layer for water mass that has σθ < 26.0. These types of water masses are strongly affected by mixing that is controlled by seasonal variability, fresh water intrusion of the Gulf of Aden Intermediate Water (GAIW), and eddies variability. Two types of mixing; isopycnal and diapycnal mixing are part of important physical phenomena that explain the change of water mass in the Red Sea. The isopycnal mixing occurs at the neutral potential density line, connecting the Red Sea with its adjacent channel, the Gulf of Aden. Diapycnal mixing is found as a dominant mixing mode in the surface of the Red Sea Water and mainly due to energetic eddy activity. Density gradients, across which diapycnal mixing occurs, in the Red Sea are mainly due to large variations in salinity. The isolation of an extreme haline water mass below the thermocline contributes to the generation of the latitudinal shift and low diapycnal mixing. This finding further explains the difference of spatial kinetic mixing between the RSW and the Indian Ocean basin.

Stabilisation/solidification of synthetic petroleum drill cuttings.

PubMed

Al-Ansary, Marwa S; Al-Tabbaa, Abir

2007-03-15

This paper presents the results of an experimental investigation into the use of stabilisation/solidification (S/S) to treat synthetic drill cuttings as a pre-treatment to landfilling or for potential re-use as construction products. Two synthetic mixes were used based on average concentrations of specific contaminates present in typical drill cuttings from the North Sea and the Red Sea areas. The two synthetic drill cuttings contained similar chloride content of 2.03% and 2.13% by weight but different hydrocarbon content of 4.20% and 10.95% by weight, respectively; hence the mixes were denoted as low and high oil content mixes, respectively. A number of conventional S/S binders were tested including Portland cement (PC), lime and blast-furnace slag (BFS), in addition to novel binders such as microsilica and magnesium oxide cement. Physical, chemical and microstructural analyses were used to compare the relative performance of the different binder mixes. The unconfined compressive strength (UCS) values were observed to cover a wide range depending on the binder used. Despite the significant difference in the hydrocarbon content in the two synthetic cuttings, the measured UCS values of the mixes with the same binder type and content were similar. The leachability results showed the reduction of the synthetic drill cuttings to a stable non-reactive hazardous waste, compliant with the UK acceptance criteria for non-hazardous landfills: (a) by most of the binders for chloride concentrations, and (b) by the 20% BFS-PC and 30% PC binders for the low oil content mix. The 30% BFS-PC binder successfully reduced the leached oil concentration of the low oil content mix to inert levels. Finally, the microstructural analysis offered valuable information on the morphology and general behaviour of the mixes that were not depicted by the other tests.

Deodorants on the European market: quantitative chemical analysis of 21 fragrances.

PubMed

Rastogi, S C; Johansen, J D; Frosch, P; Menné, T; Bruze, M; Lepoittevin, J P; Dreier, B; Andersen, K E; White, I R

1998-01-01

Deodorants are one of the most frequently used types of cosmetics and side-effects from them are common. Recent studies relate perfume allergy to this type of product. 73 deodorants were analyzed by gas chromatography--mass spectrometry for the determination of the contents of 7 wellknown fragrance allergens from the fragrance mix and 14 other commonly used fragrance materials. The deodorants were purchased at retail outlets in 5 European countries. It was found that in general, fragrance mix ingredients were more frequently present in vapo- and aerosol sprays than in roll-on products. The levels of the fragrance mix substances ranged from 0.0001-0.2355%. The products investigated contained cinnamic aldehyde and isoeugenol less frequently (17% and 29% respectively), and eugenol and geraniol most frequently (57% and 76% respectively). The 14 other fragrance materials were found in 40-97% of the deodorants, with hedione and benzyl acetate the most frequently found substances. The concentration of these 14 substances ranged from 0.0001-2.7%. It is concluded that the levels of cinnamic aldehyde and isoeugenol found in the deodorants could prove to be relevant for elicitation of contact dermatitis. No conclusions could be drawn about the other fragrance mix constituents, as threshold levels in sensitized individuals have not been investigated. Furthermore, all of the fragrance materials investigated were frequently found in deodorants and, apart from the fragrance mix ingredients, the extent of problems with sensitization to these fragrance materials is largely unknown.

New and Improved Methods of Production of Energy Rich Materials

DTIC Science & Technology

1990-11-01

present in its molecular form (with some N2 03 also present). In acid solutions above 60-65% concentration it is present as nitrosonium ions . In an excess...Electrophilic Aromatic Nitration b~y the Nitronium Ion 1.2 Effect of Nitrous Acid 1.3 Nitration of Carbazoic. 1.4 Nitration of Dibenzothiophene -1.5...HLt~ron i un Ion The nitration -of aromatic compounds can he, achieved in a variety of media. Mixed acid nitration is the most common type used in

Characteristics of vertigo and the affected vestibular nerve systems in idiopathic bilateral vestibulopathy.

PubMed

Fujimoto, Chisato; Kinoshita, Makoto; Kamogashira, Teru; Egami, Naoya; Sugasawa, Keiko; Yamasoba, Tatsuya; Iwasaki, Shinichi

2016-01-01

Vertigo attacks in IBV patients involving both the superior and inferior vestibular nerve systems were significantly more severe than vertigo attacks in patients with selective involvement of the inferior vestibular nerve system alone. To investigate the relationship between the frequency and duration of vertigo and the affected vestibular nerve system in idiopathic bilateral vestibulopathy (IBV). This study categorized 44 IBV patients into the following three sub-groups according to the affected vestibular nerve system: superior, inferior, and mixed type. These patients were also categorized into the following three sub-groups according to their clinical time course: progressive type showing no episodes of vertigo, sequential type showing recurrent vertigo attacks and single-attack type showing a single episode of vertigo. Ten, 11 and 23 patients were classified as the superior, the inferior, and the mixed type, respectively. Seventeen, 23, and four patients were classified as the progressive, the sequential, and the single-attack type, respectively. For the patients having one or more vertigo attacks, the duration of the vertigo attack was longer than 24 h in 69% of the mixed type, and the duration of vertigo in the mixed type was significantly longer than that in the inferior type (p < 0.05).

29 CFR 1926.14 - Federal contract for “mixed” types of performance.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Interpretations § 1926.14 Federal contract for “mixed” types of performance. (a) It is the intent of the Congress... that when a Federal contract calls for mixed types of performance, such as both manufacturing and... the mixed types of performances include both construction and manufacturing, see also § 1926.15(b...

29 CFR 1926.14 - Federal contract for “mixed” types of performance.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Interpretations § 1926.14 Federal contract for “mixed” types of performance. (a) It is the intent of the Congress... that when a Federal contract calls for mixed types of performance, such as both manufacturing and... the mixed types of performances include both construction and manufacturing, see also § 1926.15(b...

29 CFR 1926.14 - Federal contract for “mixed” types of performance.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Interpretations § 1926.14 Federal contract for “mixed” types of performance. (a) It is the intent of the Congress... that when a Federal contract calls for mixed types of performance, such as both manufacturing and... the mixed types of performances include both construction and manufacturing, see also § 1926.15(b...

Design and simulation of the micromixer with chaotic advection in twisted microchannels.

PubMed

Jen, Chun-Ping; Wu, Chung-Yi; Lin, Yu-Cheng; Wu, Ching-Yi

2003-05-01

Chaotic mixers with twisted microchannels were designed and simulated numerically in the present study. The phenomenon whereby a simple Eulerian velocity field may generate a chaotic response in the distribution of a Lagrangian marker is termed chaotic advection. Dynamic system theory indicates that chaotic particle motion can occur when a velocity field is either two-dimensional and time-dependent, or three-dimensional. In the present study, micromixers with three-dimensional structures of the twisted microchannel were designed in order to induce chaotic mixing. In addition to the basic T-mixer, three types of micromixers with inclined, oblique and wavelike microchannels were investigated. In the design of each twisted microchannel, the angle of the channels' bottoms alternates in each subsection. When the fluids enter the twisted microchannels, the flow sways around the varying structures within the microchannels. The designs of the twisted microchannels provide a third degree of freedom to the flow field in the microchannel. Therefore, chaotic regimes that lead to chaotic mixing may arise. The numerical results indicate that mixing occurs in the main channel and progressively larger mixing lengths are required as the Peclet number increased. The swaying of the flow in the twisted microchannel causes chaotic advection. Among the four micromixer designs, the micromixer with the inclined channel most improved mixing. Furthermore, using the inclined mixer with six subsections yielded optimum performance, decreasing the mixing length by up to 31% from that of the basic T-mixer.

Effect of Hydrochemistry on Mineral Precipitation and Textural Diversity in Serpentinization-driven Alkaline Environments; Insights from Thermal Springs in the Oman Ophiolite.

NASA Astrophysics Data System (ADS)

Bach, W.; Giampouras, M.; Garcia-Ruiz, J. M.; Garrido, C. J.; Los, C.; Fussmann, D.; Monien, P.

2017-12-01

Interactions between meteoric water and ultramafic rocks within Oman ophiolite give rise to the formation of thermal spring waters of variable composition and temperature. Discharge of two different types of water forms complex hydrological networks of streams and ponds, in which the waters mix, undergo evaporation, and take up atmospheric CO2. We conducted a pond-by-pond sampling of waters and precipitates in two spring sites within the Wadi Tayin massif, Nasif and Khafifah, and examined how hydrochemistry and associated mineral saturation states affect the variations in mineral phases and textures. Three distinctive types of waters were identified in the system: a) Mg-type (7.9 < pH < 9.5); Mg-HCO3-rich waters, b) Ca-type (pH > 11.6); Ca-OH-rich waters, and c) Mix-type (9.6 < pH < 11.5); waters arising upon mixing of Mg-type and Ca-type. PHREEQC was used to evaluate the role of mixing in aqueous speciation and the evolution of the saturation index value of different mineral phases. Mineral and textural characterization by X-ray diffraction, Raman spectroscopy and scanning electron microscopy were combined with these hydrogeochemical constraints to determine the factors controlling mineralogical and textural diversity in the system. In Ca-type waters, uptake of CO2 during the exposure of the fluids to the atmosphere is the predominant precipitation mechanism of CaCO3. High Mg:Ca ratios and high supersaturation rate of CaCO3 favor the growth of aragonite over calcite in mixed fluids. Changes in morphology and texture of aragonite crystals and crystal aggregates indicate the variations in the values of supersaturation and supersaturation rate of CaCO3 in the different water types. Brucite precipitation is common and driven by fluid mixing, while interaction with air-derived CO2 causes its alteration to hydromagnesite. The proximity of gabbroic lithologies appears to affect the presence of Al-bearing layered double hydroxides (LDHs). Furthermore, transformation of nesquehonite to dypingite in Mg-type waters record a shift towards more alkaline conditions due to occasional mixing. This study demonstrates that water mixing, atmospheric CO2 up-take, and evaporation are the main drivers of precipitation and textural differentiation of minerals occurring in serpentinization-driven alkaline environments.

Blind identification of image manipulation type using mixed statistical moments

NASA Astrophysics Data System (ADS)

Jeong, Bo Gyu; Moon, Yong Ho; Eom, Il Kyu

2015-01-01

We present a blind identification of image manipulation types such as blurring, scaling, sharpening, and histogram equalization. Motivated by the fact that image manipulations can change the frequency characteristics of an image, we introduce three types of feature vectors composed of statistical moments. The proposed statistical moments are generated from separated wavelet histograms, the characteristic functions of the wavelet variance, and the characteristic functions of the spatial image. Our method can solve the n-class classification problem. Through experimental simulations, we demonstrate that our proposed method can achieve high performance in manipulation type detection. The average rate of the correctly identified manipulation types is as high as 99.22%, using 10,800 test images and six manipulation types including the authentic image.

Mix Proportion Design of Asphalt Concrete

NASA Astrophysics Data System (ADS)

Wu, Xianhu; Gao, Lingling; Du, Shoujun

2017-12-01

Based on the gradation of AC and SMA, this paper designs a new type of anti slide mixture with two types of advantages. Chapter introduces the material selection, ratio of ore mixture ratio design calculation, and determine the optimal asphalt content test and proportioning design of asphalt concrete mix. This paper introduces the new technology of mix proportion.

7 CFR 52.1858 - Grades of mixed types or varieties of raisins.

Code of Federal Regulations, 2012 CFR

2012-01-01

... based on the respective requirements for each type, except for moisture, in accordance with this subpart... than 18 percent, by weight, of moisture. Mixed types of processed raisins that as a mixture exceed 18 percent, by weight, of moisture are “Substandard.” ...

F-16 Media Selection and Utilization Plan Report.

DTIC Science & Technology

1981-03-01

F0260A-79-C-887S Eommhhmhhhhhmu EmhEmhEEohhhEE Efl ~fflflEfl EN 11111 ~ ~ 111 5_______ III mi o - ~ I I . I 1 N I t 1 , I F16 AIRCREW TRAININgN...two to three objectives per segment, and the types of objective (and thus the type of instructional strategy required to teach it) will not be mixed... teaching of a given objective can be identified. Since the medium is the device for presenting displays and handling all interactions between the student

Blaschko-linear “Congenital Mixed Hemato-lymphangio-keratoma Serpiginosum” Naeviforme

PubMed Central

Çağlar, Aysel; Altinay, Serdar

2018-01-01

We present the case of a 15-year-old girl who presented with an unusual grouping of lesions on her upper left leg. The lesions had been present since birth. The patient had five different types of lesions: 1) transparent grouped or scattered yellowish vesicles; 2) keratotic-surfaced, grouped dark-yellowish papules; 3) bright-red grouped papules; 4) keratotic-surfaced grouped dark-red papules; and 5) patchy, punctate, and erythematous red macules. All of the lesions were intertwined along the lines of Blaschko and were in the form of irregular serpiginous plaques. Histopathological examinations of the lesions showed three main histological features, and diagnoses of the lesions were made as lymphangioma circumscriptum, lymphangiokeratoma, and verrucous hemangioma. To the best of our knowledge, such intertwined lesions have never been reported in the literature. Hence, we suggest that the name of this unique combination of lesions be “congenital nevoid mixed hemato-lymphangio-keratoma serpiginosum.”

A Mixed Kijima Model Using the Weibull-Based Generalized Renewal Processes

PubMed Central

2015-01-01

Generalized Renewal Processes are useful for approaching the rejuvenation of dynamical systems resulting from planned or unplanned interventions. We present new perspectives for the Generalized Renewal Processes in general and for the Weibull-based Generalized Renewal Processes in particular. Disregarding from literature, we present a mixed Generalized Renewal Processes approach involving Kijima Type I and II models, allowing one to infer the impact of distinct interventions on the performance of the system under study. The first and second theoretical moments of this model are introduced as well as its maximum likelihood estimation and random sampling approaches. In order to illustrate the usefulness of the proposed Weibull-based Generalized Renewal Processes model, some real data sets involving improving, stable, and deteriorating systems are used. PMID:26197222

Layered Na‐Ion Cathodes with Outstanding Performance Resulting from the Synergetic Effect of Mixed P‐ and O‐Type Phases

PubMed Central

Keller, Marlou

2015-01-01

Herein, the synthesis of new quaternary layered Na‐based oxides of the type NaxMnyNizFe0.1Mg0.1O2 (0.67≤ x ≤ 1.0; 0.5≤ y ≤ 0.7; 0.1≤ z ≤ 0.3) is described. The synthesis can be tuned to obtain P2‐ and O3‐type as well as mixed P‐/O‐type phases as demonstrated by structural, morphological, and electrochemical properties characterization. Although all materials show good electrochemical performance, the simultaneous presence of the P‐ and O‐type phases is found to have a synergetic effect resulting in outstanding performance of the mixed phase material as a sodium‐ion cathode. The mixed P3/P2/O3‐type material, having an average elemental composition of Na0.76Mn0.5Ni0.3Fe0.1Mg0.1O2, overcomes the specific drawbacks associated with the P2‐ and O3‐type materials, allowing the outstanding electrochemical performance. In detail, the mixed phase material is able to deliver specific discharge capacities of up to 155 mAh g−1 (18 mA g−1) in the potential range of 2.0–4.3 V. In the narrower potential range of 2.5–4.3 V the material exhibits high average discharge potential (3.4 V versus Na/Na+), exceptional average coulombic efficiencies (>99.9%), and extraordinary capacity retention (90.2% after 601 cycles). The unexplored class of P‐/O‐type mixed phases introduces new perspectives for the development of layered positive electrode materials and powerful Na‐ion batteries. PMID:27134617

Microgravity acoustic mixing for particle cloud combustors

NASA Technical Reports Server (NTRS)

Pla, Frederic; Rubinstein, Robert I.

1990-01-01

Experimental and theoretical investigations of acoustic mixing procedures designed to uniformly distribute fuel particles in a combustion tube for application in the proposed Particle Cloud Combustion Experiment (PCCE) are described. Two acoustic mixing methods are investigated: mixing in a cylindrical tube using high frequency spinning modes generated by suitably phased, or quadrature speakers, and acoustic premixing in a sphere. Quadrature mixing leads to rapid circumferential circulation of the powder around the tube. Good mixing is observed in the circulating regions. However, because axial inhomogeneities are necessarily present in the acoustic field, this circulation does not extend throughout the tube. Simultaneous operation of the quadrature-speaker set and the axial-speaker was observed to produce considerably enhanced mixing compared to operation of the quadrature-speaker set alone. Mixing experiments using both types of speakers were free of the longitudinal powder drift observed using axial-speakers alone. Vigorous powder mixing was obtained in the sphere for many normal modes: however, in no case was the powder observed to fill the sphere entirely. Theoretical analysis indicated that mixing under steady conditions cannot fill more than a hemisphere except under very unusual conditions. Premixing in a hemisphere may be satisfactory; otherwise, complete mixing in microgravity might be possible by operating the speaker in short bursts. A general conclusion is that acoustic transients are more likely to produce good mixing than steady state conditions. The reason is that in steady conditions, flow structures like nodal planes are possible and often even unavoidable. These tend to separate the mixing region into cells across which powder cannot be transferred. In contrast, transients not only are free of such structures, they also have the characteristics, desirable for mixing, of randomness and disorder. This conclusion is corroborated by mixing experiments using axial waves.

Community type classification of forest vegetation in young, mixed stands, interior Alaska.

Treesearch

Andrew Youngblood

1993-01-01

A total of 53 upland mixed communities were sampled and classified into five community types: Populus tremuloides/Arctostaphylos uva-ursi, Populus tremuloides/Shepherdla canadensis, Betula papyrifera-Populus tremuloides/Viburnum edule, Betula papyrifera-Populus tremuloldes/Alnus crispa and Picea glauca-Betula papyrlfera/Hylocomlum splendens. Community types were...

BeiDou inter-satellite-type bias evaluation and calibration for mixed receiver attitude determination.

PubMed

Nadarajah, Nandakumaran; Teunissen, Peter J G; Raziq, Noor

2013-07-22

The Chinese BeiDou system (BDS), having different types of satellites, is an important addition to the ever growing system of Global Navigation Satellite Systems (GNSS). It consists of Geostationary Earth Orbit (GEO) satellites, Inclined Geosynchronous Satellite Orbit (IGSO) satellites and Medium Earth Orbit (MEO) satellites. This paper investigates the receiver-dependent bias between these satellite types, for which we coined the name "inter-satellite-type bias" (ISTB), and its impact on mixed receiver attitude determination. Assuming different receiver types may have different delays/biases for different satellite types, we model the differential ISTBs among three BeiDou satellite types and investigate their existence and their impact on mixed receiver attitude determination. Our analyses using the real data sets from Curtin's GNSS array consisting of different types of BeiDou enabled receivers and series of zero-baseline experiments with BeiDou-enabled receivers reveal the existence of non-zero ISTBs between different BeiDou satellite types. We then analyse the impact of these biases on BeiDou-only attitude determination using the constrained (C-)LAMBDA method, which exploits the knowledge of baseline length. Results demonstrate that these biases could seriously affect the integer ambiguity resolution for attitude determination using mixed receiver types and that a priori correction of these biases will dramatically improve the success rate.

Periodontal disease detection in primary and mixed dentitions.

PubMed

Nobre, C M Guimarães; Fernandes-Costa, A N; de Melo Soares, M S; Pugliesi, D M Carvalho; de Vasconcelos Gurgel, B C

2016-10-01

This was to compare the periodontal status of children with primary and mixed dentition at the time of their first consultation. Children (200), aged 0-12 years (156 with mixed and 44 with primary dentition), were examined by assessing their simplified plaque index (PI) and simplified periodontal record (PSR). Statistical analysis (Chi-square test) was performed with appropriate software to find any significant associations between sex, type of dentition and PI with the PSR codes (0, 1, 2, 3 and 4). There was no statistically significant difference with regard to gender (p = 0.82). Generalised PI was associated more significantly with mixed dentition (p = 0.025 and higher PSR scores (p < 0.001). There was no significant relationship between sex and PSR codes (p = 0.82). Children presenting with a mixed dentition had worse PI values and PSR scores. It is important to perform periodontal examination in children to diagnose and prevent future periodontal disease and maintain their dentition as well as to identify any associated systemic conditions.

Mix Models Applied to the Pushered Single Shell Capsules Fired on NIF1

NASA Astrophysics Data System (ADS)

Tipton, Robert; Dewald, Eduard; Pino, Jesse; Ralph, Joe; Sacks, Ryan; Salmonson, Jay

2017-10-01

The goal of the Pushered Single Shell (PSS) experimental campaign is to study the mix of partially ionized ablator material into the hotspot. To accomplish this goal, we used a uniformly Si doped plastic capsule based on the successful Two-Shock campaign. The inner few microns of the capsule can be doped with a few percent Ge. To diagnose mix, we used the method of separated reactants; deuterating the inner Ge-doped layer, CD/Ge, while using a gas fill of Tritium and Hydrogen. Mix is inferred by measuring the neutron yields from DD, DT, and TT reactions. The PSS implosion is fast ( 400 km/sec), hot ( 3KeV) and round (P2 0). This paper will present the calculations of RANS type mix models such as KL along with LES models such as multicomponent Navier Stokes on several PSS shots. The calculations will be compared to each other and to the measured data. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract No. DE-AC52-07NA27344.

Computational Model Prediction and Biological Validation Using Simplified Mixed Field Exposures for the Development of a GCR Reference Field

NASA Technical Reports Server (NTRS)

Hada, M.; Rhone, J.; Beitman, A.; Saganti, P.; Plante, I.; Ponomarev, A.; Slaba, T.; Patel, Z.

2018-01-01

The yield of chromosomal aberrations has been shown to increase in the lymphocytes of astronauts after long-duration missions of several months in space. Chromosome exchanges, especially translocations, are positively correlated with many cancers and are therefore a potential biomarker of cancer risk associated with radiation exposure. Although extensive studies have been carried out on the induction of chromosomal aberrations by low- and high-LET radiation in human lymphocytes, fibroblasts, and epithelial cells exposed in vitro, there is a lack of data on chromosome aberrations induced by low dose-rate chronic exposure and mixed field beams such as those expected in space. Chromosome aberration studies at NSRL will provide the biological validation needed to extend the computational models over a broader range of experimental conditions (more complicated mixed fields leading up to the galactic cosmic rays (GCR) simulator), helping to reduce uncertainties in radiation quality effects and dose-rate dependence in cancer risk models. These models can then be used to answer some of the open questions regarding requirements for a full GCR reference field, including particle type and number, energy, dose rate, and delivery order. In this study, we designed a simplified mixed field beam with a combination of proton, helium, oxygen, and iron ions with shielding or proton, helium, oxygen, and titanium without shielding. Human fibroblasts cells were irradiated with these mixed field beam as well as each single beam with acute and chronic dose rate, and chromosome aberrations (CA) were measured with 3-color fluorescent in situ hybridization (FISH) chromosome painting methods. Frequency and type of CA induced with acute dose rate and chronic dose rates with single and mixed field beam will be discussed. A computational chromosome and radiation-induced DNA damage model, BDSTRACKS (Biological Damage by Stochastic Tracks), was updated to simulate various types of CA induced by acute exposures of the mixed field beams used for the experiments. The chromosomes were simulated by a polymer random walk algorithm with restrictions to their respective domains in the nucleus [1]. The stochastic dose to the nucleus was calculated with the code RITRACKS [2]. Irradiation of a target volume by a mixed field of ions was implemented within RITRACKs, and the fields of ions can be delivered over specific periods of time, allowing the simulation of dose-rate effects. Similarly, particles of various types and energies extracted from a pre-calculated spectra of galactic cosmic rays (GCR) can be used in RITRACKS. The number and spatial location of DSBs (DNA double-strand breaks) were calculated in BDSTRACKS using the simulated chromosomes and local (voxel) dose. Assuming that DSBs led to chromosome breaks, and simulating the rejoining of damaged chromosomes occurring during repair, BDSTRACKS produces the yield of various types of chromosome aberrations as a function of time (only final yields are presented). A comparison between experimental and simulation results will be shown.

Evaluation of Foaming Performance of Bitumen Modified with the Addition of Surface Active Agent

NASA Astrophysics Data System (ADS)

Chomicz-Kowalska, Anna; Mrugała, Justyna; Maciejewski, Krzysztof

2017-10-01

The article presents the analysis of the performance of foamed bitumen modified using surface active agents. Although, bitumen foaming permits production of asphalt concrete and other asphalt mix types without using chemical additives in significantly reduced temperatures, the decrease in processing temperatures still impacts the adhesion performance and bitumen coating of aggregates in final mixes. Therefore, in some cases it may be feasible to incorporate adhesion promoters and surface active agents into warm and half-warm mixes with foamed bitumen to increase their service life and resilience. Because of the various nature of the available surface active agents, varying bitumen compatibility and their possible impact on the rheological properties of bitumen, the introduction of surface active agents may significantly alter the bitumen foaming performance. The tests included basic performance tests of bitumen before and after foaming. The two tested bitumen were designated as 35/50 and 50/70 penetration grade binders, which were modified with a surface active agent widely used for improving mixture workability, compactibility and adhesion in a wide range of asphalt mixes and techniques, specifically Warm Mix Asphalt. Alongside to the reference unmodified bitumen, binders with 0.2%, 0.4% and 0.6% surface active agent concentration were tested. The analysis has shown a positive influence of the modifier on the foaming performance of both of the base bitumen increasing their maximum expansion ratio and bitumen foam halflife. In the investigations, it was found that the improvement was dependent on the bitumen type and modifier content. The improved expansion ratio and foam half-life has a positive impact on the aggregate coating and adhesion, which together with the adhesion promoting action of the modifier will have a combined positive effect on the quality of produced final asphalt mixes.

Importance of the mixing state for ice nucleating capabilities of individual aerosol particles

NASA Astrophysics Data System (ADS)

Ebert, Martin; Worringen, Annette; Benker, Nathalie; Weinbruch, Stephan

2010-05-01

The effects of aerosol particles on heterogeneous ice formation are currently insufficiently understood. Modelling studies have shown that the type and quantity of atmospheric aerosol particles acting as ice nuclei (IN) can influence ice cloud microphysical and radiative properties as well as their precipitation efficiency. Therefore, the physicochemical identification of IN and a quantitative description of the ice nucleation processes are crucial for a better understanding of formation, life cycles, and the optical properties of clouds as well as for numerical precipitation forecast. During the CLACE 5 campaign in 2006 at the high alpine research station Jungfraujoch (3580 m asl), Switzerland, the physicochemical parameters of IN within mixed-phase clouds were studied. By the use of special Ice-Counterflow Virtual Impactor, residual particles of small ice nuclei (IN) and the interstitial aerosol fraction were sampled seperately within mixed-phase clouds. The size, morphology, elemental composition and mixing state of more than 7000 particles of selected IN- and interstitial-samples were analyzed by scanning electron microscopy (SEM) combined with energy-dispersive X-ray analysis (EDX). For selected particles, the mineralogical phase composition was determined by transmission electron microscopy. In order to receive detailed information about the mixing state (coatings, agglomerates, heterogeneous inclusions) of the IN- and interstitial-samples, the complete individual particle analysis was performed operator controlled. Four different particle types were identified to act as IN. 1) Carbonaceous particles, which were identified to be a complex mixture of soot (main component), sulfate and nitrate. 2) Complex mixtures of two or more diverse particle groups. In almost 75% of these particles silicates or metal oxides are the main-component. 3) Aluminium oxide particles, which were internally mixed with calcium and sulphate rich material and 4) Pb bearing particles. The high abundance of Pb-bearing particles in the IN-samples (up to 24% by number) was an unexpected finding. Besides a smaller content of larger PbO and PbCl2-particles the main component of the particles within this type are predominantly sea salt, soot or silicates, while Pb in these particles is only present as small (50 - 500 nm) heterogeneous Pb or PbS inclusions. In all 4 particle types identified as IN, the mixing state seems to play an essential role. Therefore it can be concluded that the determination of the main-component of a particle is not sufficient for the prediction of its IN-capability.

An investigation of the bacteriological quality of retail vanilla slices.

PubMed Central

Pinegar, J. A.; Buxton, J. D.

1977-01-01

One hundred and thiry-three vanilla slices, purchased from shops in the West Yorkshire Metropolitan County, were examined to determine the numbers and types of bacteria present at the time of purchase. The surface colony count at 37 degrees C was greater than 10(3)/g in 67/133 (50%) of the samples examined, Bacillus cereus being found at that concentration in 21.8%, coliform bacilli including E. coli in 5.3%, Staphylococcus aureus in 3-0% and Streptococcus faecalis in 0-8%. Thirty-four strains of B. cereus were serotyped and 11 (32%) of these were typable with the sera available. Preparation of custard mixed in the laboratory suggests that the milk or milk powder used in the mix may be the major source of B. cereus in the final product. Many of the present methods of manufacture, distribution and storage allow organisms present in the custard at manufacture the opportunity to multiply and possibly reach numbers which present a risk of food poisoning. PMID:405420

Construction of In-house Databases in a Corporation

NASA Astrophysics Data System (ADS)

Nishikawa, Takaya

The author describes the progress in and present status of the information management system at the research laboratories as a R & D component of pharmaceutical industry. The system deals with three fundamental types of information, that is, graphic information, numeral information and textual information which includes the former two types of information. The author and others have constructed the system which enables to process these kinds of information integrally. The system is also featured by the fact that natural form of information in which Japanese words (2 byte type) and English (1 byte type) as culture of personal & word processing computers are mixed can be processed by large-size computers because Japanese language are eligible for computer processing. The system is originally for research administrators, but can be effective also for researchers. At present 7 databases are available including external databases. The system is always ready to accept other databases newly.

Some Remarks on Practical Aspects of Laboratory Testing of Deep Soil Mixing Composites Achieved in Organic Soils

NASA Astrophysics Data System (ADS)

Kanty, Piotr; Rybak, Jarosław; Stefaniuk, Damian

2017-10-01

This paper presents the results of laboratory testing of organic soil-cement samples are presented in the paper. The research program continues previously reported the authors’ experiences with cement-fly ash-soil sample testing. Over 100 of compression and a dozen of tension tests have been carried out altogether. Several samples were waiting for failure test for over one year after they were formed. Several factors, like: the large amount of the tested samples, a long observation time, carrying out the tests in complex cycles of loading and the possibility of registering the loads and deformation in the axial and lateral direction - have made it possible to take into consideration numerous interdependencies, three of which have been presented in this work: the increments of compression strength, the stiffness of soil-cement in relation to strength and the tensile strength. Compressive strength, elastic modulus and tensile resistance of cubic samples were examined. Samples were mixed and stored in the laboratory conditions. Further numerical analysis in the Finite Element Method numerical code Z_Soil, were performed on the basis of laboratory test results. Computations prove that cement-based stabilization of organic soil brings serious risks (in terms of material capacity and stiffness) and Deep Soil Mixing technology should not be recommended for achieving it. The numerical analysis presented in the study below includes only one type of organic and sandy soil and several possible geometric combinations. Despite that, it clearly points to the fact that designing the DSM columns in the organic soil may be linked with a considerable risk and the settlement may reach too high values. During in situ mixing, the organic material surrounded by sand layers surely mixes with one another in certain areas. However, it has not been examined and it is difficult to assume such mixing already at the designing stage. In case of designing the DSM columns which goes through a thin layer of organic soil it is recommended to carry out each time the core drilling which checks the degree of material mixing and their strength.

Isolation of cholinesterase and β-secretase 1 inhibiting compounds from Lycopodiella cernua.

PubMed

Nguyen, Van Thu; To, Dao Cuong; Tran, Manh Hung; Oh, Sang Ho; Kim, Jeong Ah; Ali, Md Yousof; Woo, Mi-Hee; Choi, Jae Sue; Min, Byung Sun

2015-07-01

Three new serratene-type triterpenoids (1-3) and a new hydroxy unsaturated fatty acid (13) together with nine known compounds (4-12) were isolated from Lycopodiella cernua. The chemical structures were established using NMR, MS, and Mosher's method. Compound 13 showed the most potent inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.22μM. For butyrylcholinesterase (BChE) inhibitory activity, 5 showed the most potent activity with an IC50 value of 0.42μM. Compound 2 showed the most potent activity with an IC50 of 0.23μM for BACE-1 inhibitory activity. The kinetic activities were investigated to determine the type of enzyme inhibition involved. The types of AChE inhibition shown by compounds 4, 5, and 13 were mixed; BChE inhibition by 5 was competitive, while 2 and 6 showed mixed-types. In addition, molecular docking studies were performed to investigate the interaction of these compounds with the pocket sites of AChE. The docking results revealed that the tested inhibitors 3, 4, and 13 were stably present in several pocket domains of the AChE residue. Copyright © 2015 Elsevier Ltd. All rights reserved.

[Treatment of lymphangioma with OK-432 infiltration].

PubMed

Rodríguez, J; Cáceres, F; Vargas, P

2012-10-01

The management of lymphangioma using sclerotherapy has proven to be an effective therapeutic. Our aim was to evaluate the therapeutic efficacy of OK-432 (Picibanil) in patients with lymphagioma. The study was performed from November 2010 to July 2011. Fifteen patients of both genders were diagnosed with lymphangioma, 12 days to 12 years old. All patients were infiltrated with OK-432. The studied variables were: previous surgery, localization, type of lymphangioma, number of effective injections, reduction of mass valued as excellent (100% reduction), good (reduction > 50%) and bad (reduction < 50%), presence of recurrence and complications. 40% of pacients had prior surgery and 53.3% were located in the cervical-face region. The type of macrocystic lymphangioma was present in 40% of the series, mixed type in 46.6% and microcystic type in 13.4%. The number of effective infiltrations were 3. In 6 cases (40%) the result was excellent in 5 cases (33.4%) the result was good and in 4 cases (26.6%). We had 1 recurrence (6.6%) and we haven't had complications. Injection of OK-432 in macrocystic lymphangioma and mixed had a safe therapeutic modality with satisfactory results. So it is a valid alternative to conventional surgery.

False Equivalency: Think Tank References on Education in the News Media

ERIC Educational Resources Information Center

Haas, Eric

2007-01-01

This study explores the use and presentation of information and research on education by the news media. Using content analysis, this study compares four types of think tanks--contract research, academic, advocacy, and mixed academic and advocacy--and shows how the news media represented each one as a source of research, facts, and figures on…

Batter's Choice and Differentiated Pitch Levels in Softball: A Student-Centered Approach

ERIC Educational Resources Information Center

Olsen, Edward B.

2015-01-01

Teaching youth softball presents several challenges to practitioners. Chief among these are the mixed ability levels, backgrounds and knowledge students have of certain games. The other problem is the "one size fits all" approach to pitching and hitting. In other words, many softball units allow for only one standard type of pitch…

Judged Similarity of Aptitude and Achievement Tests in Mathematics.

ERIC Educational Resources Information Center

Donlon, Thomas F.

This study attempts to establish the ability of a panel of five judges with varied mathematics background to distinguish between two types of mathematical tests by separating their component items when they are presented in a mixed pool of aptitude and achievement tests. Typically, the two tests show high correlation. The judges showed about 70%…

Effects of Providing a Rationale for Learning a Lesson on Students' Motivation and Learning in Online Learning Environments

ERIC Educational Resources Information Center

Shin, Tae Seob

2010-01-01

This study examined whether providing a rationale for learning a particular lesson influences students' motivation and learning in online learning environments. A mixed-method design was used to investigate the effects of two types of rationales (former student vs. instructor rationales) presented in an online introductory educational psychology…

Affirming Children's Roots: Cultural and Linguistic Diversity in Early Care and Education.

ERIC Educational Resources Information Center

Chang, Hedy Nai-Lin

This report documents for the first time the growing ethnic mix of center-based child care in California. Based on a survey of 434 centers in 5 California counties selected for their ethnic and geographic diversity and large child populations, the report presents several types of information. First, it documents the scope of the demographic…

Regression analysis of mixed recurrent-event and panel-count data.

PubMed

Zhu, Liang; Tong, Xinwei; Sun, Jianguo; Chen, Manhua; Srivastava, Deo Kumar; Leisenring, Wendy; Robison, Leslie L

2014-07-01

In event history studies concerning recurrent events, two types of data have been extensively discussed. One is recurrent-event data (Cook and Lawless, 2007. The Analysis of Recurrent Event Data. New York: Springer), and the other is panel-count data (Zhao and others, 2010. Nonparametric inference based on panel-count data. Test 20: , 1-42). In the former case, all study subjects are monitored continuously; thus, complete information is available for the underlying recurrent-event processes of interest. In the latter case, study subjects are monitored periodically; thus, only incomplete information is available for the processes of interest. In reality, however, a third type of data could occur in which some study subjects are monitored continuously, but others are monitored periodically. When this occurs, we have mixed recurrent-event and panel-count data. This paper discusses regression analysis of such mixed data and presents two estimation procedures for the problem. One is a maximum likelihood estimation procedure, and the other is an estimating equation procedure. The asymptotic properties of both resulting estimators of regression parameters are established. Also, the methods are applied to a set of mixed recurrent-event and panel-count data that arose from a Childhood Cancer Survivor Study and motivated this investigation. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

GiniClust: detecting rare cell types from single-cell gene expression data with Gini index.

PubMed

Jiang, Lan; Chen, Huidong; Pinello, Luca; Yuan, Guo-Cheng

2016-07-01

High-throughput single-cell technologies have great potential to discover new cell types; however, it remains challenging to detect rare cell types that are distinct from a large population. We present a novel computational method, called GiniClust, to overcome this challenge. Validation against a benchmark dataset indicates that GiniClust achieves high sensitivity and specificity. Application of GiniClust to public single-cell RNA-seq datasets uncovers previously unrecognized rare cell types, including Zscan4-expressing cells within mouse embryonic stem cells and hemoglobin-expressing cells in the mouse cortex and hippocampus. GiniClust also correctly detects a small number of normal cells that are mixed in a cancer cell population.

Mixing in microfluidic devices and enhancement methods

PubMed Central

Ward, Kevin; Fan, Z Hugh

2015-01-01

Mixing in microfluidic devices presents a challenge due to laminar flows in microchannels, which result from low Reynolds numbers determined by the channel’s hydraulic diameter, flow velocity, and solution’s kinetic viscosity. To address this challenge, novel methods of mixing enhancement within microfluidic devices have been explored for a variety of applications. Passive mixing methods have been created, including those using ridges or slanted wells within the microchannels, as well as their variations with improved performance by varying geometry and patterns, by changing the properties of channel surfaces, and by optimization via simulations. In addition, active mixing methods including microstirrers, acoustic mixers, and flow pulsation have been investigated and integrated into microfluidic devices to enhance mixing in a more controllable manner. In general, passive mixers are easy to integrate, but difficult to control externally by users after fabrication. Active mixers usually take efforts to integrate within a device and they require external components (e.g. power sources) to operate. However, they can be controlled by users to a certain degree for tuned mixing. In this article, we provide a general overview of a number of passive and active mixers, discuss their advantages and disadvantages, and make suggestions on choosing a mixing method for a specific need as well as advocate possible integration of key elements of passive and active mixers to harness the advantages of both types. PMID:26549938

Mixing in microfluidic devices and enhancement methods.

PubMed

Ward, Kevin; Fan, Z Hugh

2015-09-01

Mixing in microfluidic devices presents a challenge due to laminar flows in microchannels, which result from low Reynolds numbers determined by the channel's hydraulic diameter, flow velocity, and solution's kinetic viscosity. To address this challenge, novel methods of mixing enhancement within microfluidic devices have been explored for a variety of applications. Passive mixing methods have been created, including those using ridges or slanted wells within the microchannels, as well as their variations with improved performance by varying geometry and patterns, by changing the properties of channel surfaces, and by optimization via simulations. In addition, active mixing methods including microstirrers, acoustic mixers, and flow pulsation have been investigated and integrated into microfluidic devices to enhance mixing in a more controllable manner. In general, passive mixers are easy to integrate, but difficult to control externally by users after fabrication. Active mixers usually take efforts to integrate within a device and they require external components (e.g. power sources) to operate. However, they can be controlled by users to a certain degree for tuned mixing. In this article, we provide a general overview of a number of passive and active mixers, discuss their advantages and disadvantages, and make suggestions on choosing a mixing method for a specific need as well as advocate possible integration of key elements of passive and active mixers to harness the advantages of both types.

Effect of Mixing Dyes and Solvent in Electrolyte Toward Characterization of Dye Sensitized Solar Cell Using Natural Dyes as The Sensitizer

NASA Astrophysics Data System (ADS)

Puspitasari, Nurrisma; Nurul Amalia, Silviyanti S.; Yudoyono, Gatut; Endarko

2017-07-01

Dye Sensitized Solar Cell (DSSC) using natural dyes (chlorophyll, curcumin from turmeric extract, and anthocyanin from mangosteen extract) have been successfully fabricated for determining the effect of variation natural dyes, mixing dyes and acetonitrile in electrolyte toward characterization of DSSC. DSSC consists of five parts namely ITO (Indium Tin Oxide) as a substrate; TiO2 as semiconductor materials; natural dyes as an electron donor; electrolyte as electron transfer; and carbon as a catalyst that can convert light energy into electric energy. Two types of gel electrolyte based on PEG that mixed with liquid electrolyte have utilized for analyzing the lifetime of DSSC. Type I used distilled water as a solvent whilst type II used acetonitrile as a solvent with addition of concentration of KI and iodine. The main purpose of study was to investigate influence of solvent in electrolyte, variation of natural dyes and mixing dyes toward an efficiency that resulted by DSSC. The result showed that electrolyte type II is generally better than type I with efficiency 0,0556 and 0,0456 %, respectively. An efficiency values which resulted from a variation of mixed three natural dyes showed the greatest efficiency compared to mixed two natural dyes and one dye, with an efficiency value can be achieved at 0,0194 % for chlorophyll; 0,111 % for turmeric; 0,0105 % for mangosteen; 0,0244% (mangosteen and chlorophyll); 0,0117 % (turmeric and mangosteen); 0,0158 % (turmeric and chlorophyll); and 0.0566 % (mixed three natural dyes).

Nanohole Arrays of Mixed Designs and Microwriting for Simultaneous and Multiple Protein Binding Studies

PubMed Central

Ji, Jin; Yang, Jiun-Chan; Larson, Dale N.

2009-01-01

We demonstrate using nanohole arrays of mixed designs and a microwriting process based on dip-pen nanolithography to monitor multiple, different protein binding events simultaneously in real time based on the intensity of Extraordinary Optical Transmission of nanohole arrays. The microwriting process and small footprint of the individual nanohole arrays enabled us to observe different binding events located only 16μm apart, achieving high spatial resolution. We also present a novel concept that incorporates nanohole arrays of different designs to improve confidence and accuracy of binding studies. For proof of concept, two types of nanohole arrays, designed to exhibit opposite responses to protein bindings, were fabricated on one transducer. Initial studies indicate that the mixed designs could help to screen out artifacts such as protein intrinsic signals, providing improved accuracy of binding interpretation. PMID:19297143

Robust passivity analysis for discrete-time recurrent neural networks with mixed delays

NASA Astrophysics Data System (ADS)

Huang, Chuan-Kuei; Shu, Yu-Jeng; Chang, Koan-Yuh; Shou, Ho-Nien; Lu, Chien-Yu

2015-02-01

This article considers the robust passivity analysis for a class of discrete-time recurrent neural networks (DRNNs) with mixed time-delays and uncertain parameters. The mixed time-delays that consist of both the discrete time-varying and distributed time-delays in a given range are presented, and the uncertain parameters are norm-bounded. The activation functions are assumed to be globally Lipschitz continuous. Based on new bounding technique and appropriate type of Lyapunov functional, a sufficient condition is investigated to guarantee the existence of the desired robust passivity condition for the DRNNs, which can be derived in terms of a family of linear matrix inequality (LMI). Some free-weighting matrices are introduced to reduce the conservatism of the criterion by using the bounding technique. A numerical example is given to illustrate the effectiveness and applicability.

7 CFR 51.2116 - Similar varietal characteristics.

Code of Federal Regulations, 2013 CFR

2013-01-01

... types mixed with narrow types, and bitter almonds shall not be mixed with sweet almonds. Color of the kernels shall not be considered, since there is often a marked difference in skin color of kernels of the...

7 CFR 51.2116 - Similar varietal characteristics.

Code of Federal Regulations, 2014 CFR

2014-01-01

... types mixed with narrow types, and bitter almonds shall not be mixed with sweet almonds. Color of the kernels shall not be considered, since there is often a marked difference in skin color of kernels of the...

Polyvalent type IV sensitizations to multiple fragrances and a skin protection cream in a metal worker.

PubMed

Tanko, Zita; Shab, Arna; Diepgen, Thomas Ludwig; Weisshaar, Elke

2009-06-01

Fragrances are very common in everyday products. A metalworker with chronic hand eczema and previously diagnosed type IV sensitizations to epoxy resin, balsam of Peru, fragrance mix and fragrance mix II was diagnosed with additional type IV sensitizations to geraniol, hydroxycitronellal, lilial, tree moss, oak moss absolute, citral, citronellol, farnesol, Lyral, fragrance mix II and fragrance mix (with sorbitan sesquioleate). In addition, a type IV sensitization to the skin protection cream containing geraniol and citronellol used at the workplace was detected, and deemed occupationally relevant in this case. The patient could have had contact to fragrances through private use of cosmetics and detergents. On the other hand, the fragrance-containing skin protection cream supports occupational exposure. This case report demonstrates that fragrance contact allergy has to be searched for and clarified individually, which requires a thorough history and a detailed analysis of the work place.

A generalized interval fuzzy mixed integer programming model for a multimodal transportation problem under uncertainty

NASA Astrophysics Data System (ADS)

Tian, Wenli; Cao, Chengxuan

2017-03-01

A generalized interval fuzzy mixed integer programming model is proposed for the multimodal freight transportation problem under uncertainty, in which the optimal mode of transport and the optimal amount of each type of freight transported through each path need to be decided. For practical purposes, three mathematical methods, i.e. the interval ranking method, fuzzy linear programming method and linear weighted summation method, are applied to obtain equivalents of constraints and parameters, and then a fuzzy expected value model is presented. A heuristic algorithm based on a greedy criterion and the linear relaxation algorithm are designed to solve the model.

NEUTRONIC REACTOR SYSTEM

DOEpatents

Daniels, F.

1957-10-15

Gas-cooled solid-moderator type reactors wherein the fissionable fuel and moderator materials are each in the form of solid pebbles, or discrete particles, and are substantially homogeneously mixed in the proper proportion and placed within the core of the reactor are described. The shape of these discrete particles must be such that voids are present between them when mixed together. Helium enters the bottom of the core and passes through the voids between the fuel and moderator particles to absorb the heat generated by the chain reaction. The hot helium gas is drawn off the top of the core and may be passed through a heat exchanger to produce steam.

A universal quantum frequency converter via four-wave-mixing processes

NASA Astrophysics Data System (ADS)

Cheng, Mingfei; Fang, Jinghuai

2016-06-01

We present a convenient and flexible way to realize a universal quantum frequency converter by using nondegenerate four-wave-mixing processes in the ladder-type three-level atomic system. It is shown that quantum state exchange between two fields with large frequency difference can be readily achieved, where one corresponds to the atomic resonant transition in the visible spectral region for quantum memory and the other to the telecommunication range wavelength (1550 nm) for long-distance transmission over optical fiber. This method would bring great facility in realistic quantum information processing protocols with atomic ensembles as quantum memory and low-loss optical fiber as transmission channel.

Assessing and evaluating multidisciplinary translational teams: a mixed methods approach.

PubMed

Wooten, Kevin C; Rose, Robert M; Ostir, Glenn V; Calhoun, William J; Ameredes, Bill T; Brasier, Allan R

2014-03-01

A case report illustrates how multidisciplinary translational teams can be assessed using outcome, process, and developmental types of evaluation using a mixed-methods approach. Types of evaluation appropriate for teams are considered in relation to relevant research questions and assessment methods. Logic models are applied to scientific projects and team development to inform choices between methods within a mixed-methods design. Use of an expert panel is reviewed, culminating in consensus ratings of 11 multidisciplinary teams and a final evaluation within a team-type taxonomy. Based on team maturation and scientific progress, teams were designated as (a) early in development, (b) traditional, (c) process focused, or (d) exemplary. Lessons learned from data reduction, use of mixed methods, and use of expert panels are explored.

[Effect of different bone cement dispersion types in the treatment of osteoporotic vertebral compression fracture].

PubMed

Zhao, Yong-Sheng; Li, Qiang; Li, Qiang; Zheng, Yan-Ping

2017-05-25

To observe different bone cement dispersion types of PVP, PKP and manipulative reduction PVP and their effects in the treatment of senile osteoporotic vertebral compression fractures and the bone cement leakage rate. The clinical data of patients with osteoporotic vertebral compression fractures who underwent unilateral vertebroplasty from January 2012 to January 2015 was retrospectively analyzed. Of them, 56 cases including 22 males and 34 females aged from 60 to 78 years old were treated by PVP operation; Fouty-eight cases including 17 males and 31 females aged from 61 to 79 years old were treated by PKP operation; Forty-three cases including 15 males and 28 females aged from 60 to 76 years old were treated by manipulative reduction PVP operation. AP and lateral DR films were taken after the operation; the vertebral bone cement diffusion district area and mass district area were calculated with AutoCAD graphics processing software by AP and lateral DR picture, then ratio(K) of average diffusion area and mass area were calculated, defining K<50% as mass type, 50%<=K<=100% as mixed type and K>100% as diffusion type. Different bone cement dispersion types of PVP, PKP and manipulative reduction PVP operation were analyzed. According to bone cement dispersion types, patients were divided into diffusion type, mixed type and mass type groups.Visual analogue scale (VAS), vertebral body compression rate, JOA score and bone cement leakage rate were observed. All patients were followed up for 12-24 months with an average of 17.2 months. There was significant difference in bone cement dispersion type among three groups ( P <0.05). The constituent ratio of diffusion type, mixed type and mass type in PVP operation was 46.43%, 35.71%, 17.86%, in PKP was 16.67%, 37.50% , 45.83%, and in manipulative reduction PVP was 37.21%, 44.19% and 18.60%, respectively. PVP operation and manipulative reduction PVP were mainly composed of diffusion type and mixed type, while PKP was mainly composed of mass type and mixed type. There was no significant difference in VAS score, JOA score and bone cement leakage rate among three groups. There was statistically significant difference in postoperative vertebral body compression rate among three bone cement dispersion types( P <0.05), postoperative vertebral body compression rate in diffusion type group at 24 h postoperatively and final follow-up was (17.31±5.06)% and(18.58±4.91)%, respectively. In mixed type group, it was(14.21±5.15)% and(14.59±5.07)%, respectively. In mass type group, it was(13.89±5.02)% and(14.28±4.94)%, respectively. Bone cement dispersion type is different in PVP, PKP and manipulative reduction PVP operation. The bone cement dispersion of mass type and mixed type to recovery of compressed vertebral body is better than diffusion type, and there is no obvious difference in clinical effect in different bone cement dispersion type early and middle term.

An immunohistochemical study of the endocrine pancreas in raptors.

PubMed

Palmieri, C; Shivaprasad, H L

2014-12-01

The cytoarchitecture of the endocrine pancreas of 10 raptors (golden eagles, peregrine falcons, Saker falcon, turkey vultures, red-tailed hawk and unspecified falcon) was examined by immunohistochemistry. Three islet types were identified: type A mixed islets composed mainly by glucagon (A)-secreting cells, type B mixed islets with predominantly insulin (B)-secreting cell component and type M mixed islets (type M) consisting of variable number of glucagon-, insulin- and somatostatin (D)-secreting cells. The latter were further characterized into Type I, II or III according to the cell distribution of the three cell types. A and D cells were also randomly scattered within the exocrine pancreas. The results of this study suggest that the classical concept in birds of a segregation of A and B cells in well-defined and distinct islets is not applicable in raptors, reflecting an evolutionary adaptation to different dietary habits and variation in developmental mechanisms. Copyright © 2014 Elsevier Ltd. All rights reserved.

Service mix in the hospital outpatient department: implications for Medicare payment reform.

PubMed Central

Miller, M E; Sulvetta, M B; Englert, E

1995-01-01

OBJECTIVE. To determine if implementation of a PPS for Medicare hospital outpatient department (HOPD) services will have distributional consequences across hospital types and regions, this analysis assesses variation in service mix and the provision of high-technology services in the HOPD. DATA. HCFA's 1990 claims file for a 5 percent random sample of Medicare beneficiaries using the HOPD was merged, by hospital provider number, with various HCFA hospital characteristic files. STUDY DESIGN. Hospital characteristics examined are urban/rural location, teaching status, disproportionate-share status, and bed size. Two analyses of HOPD services are presented: mix of services provided and the provision of high-technology services. The mix of services is measured by the percentage of services in each of 14 type-of-service categories (e.g., medical visits, advanced imaging services, diagnostic testing services). Technology provision is measured by the percentage of hospitals providing selected high-technology services. FINDINGS/CONCLUSIONS. The findings suggest that the role hospital types play in providing HOPD services warrants consideration in establishing a PPS. HOPDs in major teaching hospitals and hospitals serving a disproportionate share of the poor play an important role in providing routine visits. HOPDs in both major and minor teaching hospitals are important providers of high-technology services. Other findings have implications for the structure of an HOPD PPS as well. First, over half of the services provided in the HOPD are laboratory tests and HOPDs may have limited control over these services since they are often for patients referred from local physician offices. Second, service mix and technology provision vary markedly among regions, suggesting the need for a transition to prospective payment. Third, the organization of service supply in a region may affect service provision in the HOPD suggesting that an HOPD PPS needs to be coordinated with payment policies in competing sites of care (e.g., ambulatory surgical centers). PMID:7721585

Evaluation of Quantitative Exposure Assessment Method for Nanomaterials in Mixed Dust Environments: Application in Tire Manufacturing Facilities.

PubMed

Kreider, Marisa L; Cyrs, William D; Tosiano, Melissa A; Panko, Julie M

2015-11-01

Current recommendations for nanomaterial-specific exposure assessment require adaptation in order to be applied to complicated manufacturing settings, where a variety of particle types may contribute to the potential exposure. The purpose of this work was to evaluate a method that would allow for exposure assessment of nanostructured materials by chemical composition and size in a mixed dust setting, using carbon black (CB) and amorphous silica (AS) from tire manufacturing as an example. This method combined air sampling with a low pressure cascade impactor with analysis of elemental composition by size to quantitatively assess potential exposures in the workplace. This method was first pilot-tested in one tire manufacturing facility; air samples were collected with a Dekati Low Pressure Impactor (DLPI) during mixing where either CB or AS were used as the primary filler. Air samples were analyzed via scanning transmission electron microscopy (STEM) coupled with energy dispersive spectroscopy (EDS) to identify what fraction of particles were CB, AS, or 'other'. From this pilot study, it was determined that ~95% of all nanoscale particles were identified as CB or AS. Subsequent samples were collected with the Dekati Electrical Low Pressure Impactor (ELPI) at two tire manufacturing facilities and analyzed using the same methodology to quantify exposure to these materials. This analysis confirmed that CB and AS were the predominant nanoscale particle types in the mixing area at both facilities. Air concentrations of CB and AS ranged from ~8900 to 77600 and 400 to 22200 particles cm(-3), respectively. This method offers the potential to provide quantitative estimates of worker exposure to nanoparticles of specific materials in a mixed dust environment. With pending development of occupational exposure limits for nanomaterials, this methodology will allow occupational health and safety practitioners to estimate worker exposures to specific materials, even in scenarios where many particle types are present. © The Author 2015. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.

New generation HMA mix designs : accelerated pavement testing of a type C mix with the ALF machine.

DOT National Transportation Integrated Search

2012-09-01

Recent changes to the Texas hot-mix asphalt (HMA) mix-design procedures, such as the adaption of the higher-stiffer performance-grade asphalt-binder grades and the Hamburg test, have ensured that the mixes that are routinely used on Texas highways ar...

Creativity and executive function across manic, mixed and depressive episodes in bipolar I disorder.

PubMed

Soeiro-de-Souza, Márcio Gerhardt; Dias, Vasco Videira; Bio, Danielle Soares; Post, Robert M; Moreno, Ricardo A

2011-12-01

Creativity is a complex construct involving affective and cognitive components. Bipolar Disorder (BD) has been associated with creativity and is characterized by a wide range of affective and cognitive symptoms. Although studies of creativity in BD have tended to focus on creativity as a trait variable in medicated euthymic patients, it probably fluctuates during symptomatic states of BD. Since creativity is known to involve key affective and cognitive components, it is plausible to speculate that cognitive deficits and symptoms present in symptomatic BD could interfere with creativity. Sixty-seven BD type I patients medication free, age 18-35 years and experiencing a maniac, mixed, or depressive episodes, were assessed for creativity, executive functioning, and intelligence. Manic and mixed state patients had higher creativity scores than depressive individuals. Creativity was influenced by executive function measures only in manic patients. Intelligence did not influence creativity for any of the mood episode types. We propose that creativity in BD might be linked to the putative hyperdopaminergic state of mania and be dependent on intact executive function. Future studies should further explore the role of dopaminergic mechanisms in creativity in BD. Copyright © 2011 Elsevier B.V. All rights reserved.

CFD modeling and experimental verification of a single-stage coaxial Stirling-type pulse tube cryocooler without either double-inlet or multi-bypass operating at 30-35 K using mixed stainless steel mesh regenerator matrices

NASA Astrophysics Data System (ADS)

Dang, Haizheng; Zhao, Yibo

2016-09-01

This paper presents the CFD modeling and experimental verifications of a single-stage inertance tube coaxial Stirling-type pulse tube cryocooler operating at 30-35 K using mixed stainless steel mesh regenerator matrices without either double-inlet or multi-bypass. A two-dimensional axis-symmetric CFD model with the thermal non-equilibrium mode is developed to simulate the internal process, and the underlying mechanism of significantly reducing the regenerator losses with mixed matrices is discussed in detail based on the given six cases. The modeling also indicates that the combination of the given different mesh segments can be optimized to achieve the highest cooling efficiency or the largest exergy ratio, and then the verification experiments are conducted in which the satisfactory agreements between simulated and tested results are observed. The experiments achieve a no-load temperature of 27.2 K and the cooling power of 0.78 W at 35 K, or 0.29 W at 30 K, with an input electric power of 220 W and a reject temperature of 300 K.

Performance life of HMA mixes : final report.

DOT National Transportation Integrated Search

2016-01-01

A number of hot mix asphalt (HMA) types, such as permeable friction course (PFC), stone mastic asphalts : (SMA), performance design mixes and conventional dense graded mixes are currently used to construct or overlay : roads. One of the important inp...

A workload model and measures for computer performance evaluation

NASA Technical Reports Server (NTRS)

Kerner, H.; Kuemmerle, K.

1972-01-01

A generalized workload definition is presented which constructs measurable workloads of unit size from workload elements, called elementary processes. An elementary process makes almost exclusive use of one of the processors, CPU, I/O processor, etc., and is measured by the cost of its execution. Various kinds of user programs can be simulated by quantitative composition of elementary processes into a type. The character of the type is defined by the weights of its elementary processes and its structure by the amount and sequence of transitions between its elementary processes. A set of types is batched to a mix. Mixes of identical cost are considered as equivalent amounts of workload. These formalized descriptions of workloads allow investigators to compare the results of different studies quantitatively. Since workloads of different composition are assigned a unit of cost, these descriptions enable determination of cost effectiveness of different workloads on a machine. Subsequently performance parameters such as throughput rate, gain factor, internal and external delay factors are defined and used to demonstrate the effects of various workload attributes on the performance of a selected large scale computer system.

A self-mixing based ring-type fiber-optic acoustic sensor

NASA Astrophysics Data System (ADS)

Wang, Lutang; Wu, Chunxu; Fang, Nian

2014-07-01

A novel, simple fiber-optic acoustic sensor consisting of a self-mixing effect based laser source and a ring-type interferometer is presented. With weak external optical feedbacks, the acoustic wave signals can be detected by measuring the changes of oscillating frequency of the laser diode, induced by the disturbances of sensing fiber, with the ring-type interferometer. The operation principles of the sensor system are explored in-depth and the experimental researches are carried out. The acoustic wave signals produced by various actions, such as by pencil broken, mental pin free falling and PZT are detected for evaluating the sensing performances of the experimental system. The investigation items include the sensitivity as well as frequency responses of the sensor system. An experiment for the detection of corona discharges is carried out, which occur in a high-voltage environment between two parallel copper electrodes, under different humidity levels. The satisfied experimental results are obtained. These experimental results well prove that our proposed sensing system has very high sensitivity and excellent high frequency responses characteristics in the detections of weak, high-frequency acoustic wave signals.

Classification of Arctic, Mid-Latitude and Tropical Clouds in the Mixed-Phase Temperature Regime

NASA Astrophysics Data System (ADS)

Costa, Anja; Afchine, Armin; Luebke, Anna; Meyer, Jessica; Dorsey, James R.; Gallagher, Martin W.; Ehrlich, André; Wendisch, Manfred; Krämer, Martina

2016-04-01

The degree of glaciation and the sizes and habits of ice particles formed in mixed-phase clouds remain not fully understood. However, these properties define the mixed clouds' radiative impact on the Earth's climate and thus a correct representation of this cloud type in global climate models is of importance for an improved certainty of climate predictions. This study focuses on the occurrence and characteristics of two types of clouds in the mixed-phase temperature regime (238-275K): coexistence clouds (Coex), in which both liquid drops and ice crystals exist, and fully glaciated clouds that develop in the Wegener-Bergeron-Findeisen regime (WBF clouds). We present an extensive dataset obtained by the Cloud and Aerosol Particle Spectrometer NIXE-CAPS, covering Arctic, mid-latitude and tropical regions. In total, we spent 45.2 hours within clouds in the mixed-phase temperature regime during five field campaigns (Arctic: VERDI, 2012 and RACEPAC, 2014 - Northern Canada; mid-latitude: COALESC, 2011 - UK and ML-Cirrus, 2014 - central Europe; tropics: ACRIDICON, 2014 - Brazil). We show that WBF and Coex clouds can be identified via cloud particle size distributions. The classified datasets are used to analyse temperature dependences of both cloud types as well as range and frequencies of cloud particle concentrations and sizes. One result is that Coex clouds containing supercooled liquid drops are found down to temperatures of -40 deg C only in tropical mixed clouds, while in the Arctic and mid-latitudes no liquid drops are observed below about -20 deg C. In addition, we show that the cloud particles' aspherical fractions - derived from polarization signatures of particles with diameters between 20 and 50 micrometers - differ significantly between WBF and Coex clouds. In Coex clouds, the aspherical fraction of cloud particles is generally very low, but increases with decreasing temperature. In WBF clouds, where all cloud particles are ice, about 20-40% of the cloud particles are nevertheless classified as spherical for all temperatures, possibly indicating columnar ice crystals (see Järvinen et al, submitted to JAS 2016).

Dry forest resilience varies under simulated climate‐management scenarios in a central Oregon, USA landscape.

PubMed

Halofsky, Joshua S; Halofsky, Jessica E; Burcsu, Theresa; Hemstrom, Miles A

Determining appropriate actions to create or maintain landscapes resilient to climate change is challenging because of uncertainty associated with potential effects of climate change and their interactions with land management. We used a set of climate-informed state-and-transition models to explore the effects of management and natural disturbances on vegetation composition and structure under different future climates. Models were run for dry forests of central Oregon under a fire suppression scenario (i.e., no management other than the continued suppression of wildfires) and an active management scenario characterized by light to moderate thinning from below and some prescribed fire, planting, and salvage logging. Without climate change, area in dry province forest types remained constant. With climate change, dry mixed-conifer forests increased in area (by an average of 21–26% by 2100), and moist mixed-conifer forests decreased in area (by an average of 36–60% by 2100), under both management scenarios. Average area in dry mixed-conifer forests varied little by management scenario, but potential decreases in the moist mixed-conifer forest were lower with active management. With changing climate in the dry province of central Oregon, our results suggest the likelihood of sustaining current levels of dense, moist mixed-conifer forests with large-diameter, old trees is low (less than a 10% chance) irrespective of management scenario; an opposite trend was observed under no climate change simulations. However, results also suggest active management within the dry and moist mixed-conifer forests that creates less dense forest conditions can increase the persistence of larger-diameter, older trees across the landscape. Owing to projected increases in wildfire, our results also suggest future distributions of tree structures will differ from the present. Overall, our projections indicate proactive management can increase forest resilience and sustain some societal values, particularly in drier forest types. However, opportunities to create more disturbance-adapted systems are finite, all values likely cannot be sustained at current levels, and levels of resilience success will likely vary by dry province forest type. Land managers planning for a future without climate change may be assuming a future that is unlikely to exist.

BeiDou Inter-Satellite-Type Bias Evaluation and Calibration for Mixed Receiver Attitude Determination

PubMed Central

Nadarajah, Nandakumaran; Teunissen, Peter J. G.; Raziq, Noor

2013-01-01

The Chinese BeiDou system (BDS), having different types of satellites, is an important addition to the ever growing system of Global Navigation Satellite Systems (GNSS). It consists of Geostationary Earth Orbit (GEO) satellites, Inclined Geosynchronous Satellite Orbit (IGSO) satellites and Medium Earth Orbit (MEO) satellites. This paper investigates the receiver-dependent bias between these satellite types, for which we coined the name “inter-satellite-type bias” (ISTB), and its impact on mixed receiver attitude determination. Assuming different receiver types may have different delays/biases for different satellite types, we model the differential ISTBs among three BeiDou satellite types and investigate their existence and their impact on mixed receiver attitude determination. Our analyses using the real data sets from Curtin's GNSS array consisting of different types of BeiDou enabled receivers and series of zero-baseline experiments with BeiDou-enabled receivers reveal the existence of non-zero ISTBs between different BeiDou satellite types. We then analyse the impact of these biases on BeiDou-only attitude determination using the constrained (C-)LAMBDA method, which exploits the knowledge of baseline length. Results demonstrate that these biases could seriously affect the integer ambiguity resolution for attitude determination using mixed receiver types and that a priori correction of these biases will dramatically improve the success rate. PMID:23881141

A Spreadsheet for the Mixing of a Row of Jets with a Confined Crossflow

NASA Technical Reports Server (NTRS)

Holderman, J. D.; Smith, T. D.; Clisset, J. R.; Lear, W. E.

2005-01-01

An interactive computer code, written with a readily available software program, Microsoft Excel (Microsoft Corporation, Redmond, WA) is presented which displays 3 D oblique plots of a conserved scalar distribution downstream of jets mixing with a confined crossflow, for a single row, double rows, or opposed rows of jets with or without flow area convergence and/or a non-uniform crossflow scalar distribution. This project used a previously developed empirical model of jets mixing in a confined crossflow to create an Microsoft Excel spreadsheet that can output the profiles of a conserved scalar for jets injected into a confined crossflow given several input variables. The program uses multiple spreadsheets in a single Microsoft Excel notebook to carry out the modeling. The first sheet contains the main program, controls for the type of problem to be solved, and convergence criteria. The first sheet also provides for input of the specific geometry and flow conditions. The second sheet presents the results calculated with this routine to show the effects on the mixing of varying flow and geometric parameters. Comparisons are also made between results from the version of the empirical correlations implemented in the spreadsheet and the versions originally written in Applesoft BASIC (Apple Computer, Cupertino, CA) in the 1980's.

A Spreadsheet for the Mixing of a Row of Jets with a Confined Crossflow. Supplement

NASA Technical Reports Server (NTRS)

Holderman, J. D.; Smith, T. D.; Clisset, J. R.; Lear, W. E.

2005-01-01

An interactive computer code, written with a readily available software program, Microsoft Excel (Microsoft Corporation, Redmond, WA) is presented which displays 3 D oblique plots of a conserved scalar distribution downstream of jets mixing with a confined crossflow, for a single row, double rows, or opposed rows of jets with or without flow area convergence and/or a non-uniform crossflow scalar distribution. This project used a previously developed empirical model of jets mixing in a confined crossflow to create an Microsoft Excel spreadsheet that can output the profiles of a conserved scalar for jets injected into a confined crossflow given several input variables. The program uses multiple spreadsheets in a single Microsoft Excel notebook to carry out the modeling. The first sheet contains the main program, controls for the type of problem to be solved, and convergence criteria. The first sheet also provides for input of the specific geometry and flow conditions. The second sheet presents the results calculated with this routine to show the effects on the mixing of varying flow and geometric parameters. Comparisons are also made between results from the version of the empirical correlations implemented in the spreadsheet and the versions originally written in Applesoft BASIC (Apple Computer, Cupertino, CA) in the 1980's.

Proteolysis in tempeh-type products obtained with Rhizopus and Aspergillus strains from grass pea (Lathyrus sativus) seeds.

PubMed

Starzyńska-Janiszewska, Anna; Stodolak, Bożena; Wikiera, Agnieszka

2015-01-01

Tempeh is a food product obtained from legumes by means of solid-state fermentation with Rhizopus sp. Our previous research proved that mixed-culture inoculum may also be successfully applied. The objective of present research was to study the proteolytic activity of R. microsporus var. chinensis and A. oryzae during tempeh-type fermentation of grass pea seeds, and the effect of inoculum composition on the protein level and in vitro protein bioavailability in products. Fermentation substrate were soaked and cooked grass pea seeds. Material was mixed with single- or mixed-culture inoculum, and incubated in perforated plastic bags at 30°C for 32 hrs. In the products, the proteolytic activity (pH 3, 5 and 7), glucosamine, total protein and free amino acids levels, as well as protein in vitro bioavailability and degree of protein hydrolysis were obtained. The significant correlation was found between glucosamine content and proteolytic activity in grass pea seeds fermented with Rhizopus or Aspergillus. The activities of Rhizopus proteases were higher than Aspergillus ones, which corresponded with the degree of seed protein hydrolysis. Both strains showed the highest activity of protease at pH 3. Tempeh made with pure culture of Rhizopus had 37% protein of 69% in-vitro bioavailability. Mixed-culture fermentation improved nutritional parameters of products only when the dose of Aspergillus spores in the inoculum was equal and lower than that of Rhizopus. This process resulted in higher in-vitro bioavailability of protein, slightly more efficient protein hydrolysis and higher level of free amino acids, as compared to standard tempeh. The activity of A. oryzae in tempeh-type fermentation is beneficial as long as it does not dominate the activity and/or growth of Rhizopus strain.

Enhanced xylitol production: Expression of xylitol dehydrogenase from Gluconobacter oxydans and mixed culture of resting cell.

PubMed

Qi, Xiang-Hui; Zhu, Jing-Fei; Yun, Jun-Hua; Lin, Jing; Qi, Yi-Lin; Guo, Qi; Xu, Hong

2016-09-01

Xylitol has numerous applications in food and pharmaceutical industry, and it can be biosynthesized by microorganisms. In the present study, xdh gene, encoding xylitol dehydrogenase (XDH), was cloned from the genome of Gluconobacter oxydans CGMCC 1.49 and overexpressed in Escherichia coli BL21. Sequence analysis revealed that XDH has a TGXXGXXG NAD(H)-binding motif and a YXXXK active site motif, and belongs to the short-chain dehydrogenase/reductase family. And then, the enzymatic properties and kinetic parameter of purified recombinant XDH were investigated. Subsequently, transformations of xylitol from d-xylulose and d-arabitol, respectively, were studied through mixed culture of resting cells of G. oxydans wild-type strain and recombinant strain BL21-xdh. We obtained 28.80 g/L xylitol by mixed culture from 30 g/L d-xylulose in 28 h. The production was increased by more than three times as compared with that of wild-type strain. Furthermore, 25.10 g/L xylitol was produced by the mixed culture from 30 g/L d-arabitol in 30 h with a yield of 0.837 g/g, and the max volumetric productivity of 0.990 g/L h was obtained at 22 h. These contrast to the fact that wild-type strain G. oxydans only produced 8.10 g/L xylitol in 30 h with a yield of 0.270 g/g. To our knowledge, these values are the highest among the reported yields and productivity efficiencies of xylitol from d-arabitol with engineering strains. Copyright © 2016 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

An Evaluation of "Intentional" Weighting of Extended-Response or Constructed-Response Items in Tests with Mixed Item Types.

ERIC Educational Resources Information Center

Ito, Kyoko; Sykes, Robert C.

This study investigated the practice of weighting a type of test item, such as constructed response, more than other types of items, such as selected response, to compute student scores for a mixed-item type of test. The study used data from statewide writing field tests in grades 3, 5, and 8 and considered two contexts, that in which a single…

Eliciting mixed emotions: a meta-analysis comparing models, types, and measures.

PubMed

Berrios, Raul; Totterdell, Peter; Kellett, Stephen

2015-01-01

The idea that people can experience two oppositely valenced emotions has been controversial ever since early attempts to investigate the construct of mixed emotions. This meta-analysis examined the robustness with which mixed emotions have been elicited experimentally. A systematic literature search identified 63 experimental studies that instigated the experience of mixed emotions. Studies were distinguished according to the structure of the underlying affect model-dimensional or discrete-as well as according to the type of mixed emotions studied (e.g., happy-sad, fearful-happy, positive-negative). The meta-analysis using a random-effects model revealed a moderate to high effect size for the elicitation of mixed emotions (d IG+ = 0.77), which remained consistent regardless of the structure of the affect model, and across different types of mixed emotions. Several methodological and design moderators were tested. Studies using the minimum index (i.e., the minimum value between a pair of opposite valenced affects) resulted in smaller effect sizes, whereas subjective measures of mixed emotions increased the effect sizes. The presence of more women in the samples was also associated with larger effect sizes. The current study indicates that mixed emotions are a robust, measurable and non-artifactual experience. The results are discussed in terms of the implications for an affect system that has greater versatility and flexibility than previously thought.

Eliciting mixed emotions: a meta-analysis comparing models, types, and measures

PubMed Central

Berrios, Raul; Totterdell, Peter; Kellett, Stephen

2015-01-01

The idea that people can experience two oppositely valenced emotions has been controversial ever since early attempts to investigate the construct of mixed emotions. This meta-analysis examined the robustness with which mixed emotions have been elicited experimentally. A systematic literature search identified 63 experimental studies that instigated the experience of mixed emotions. Studies were distinguished according to the structure of the underlying affect model—dimensional or discrete—as well as according to the type of mixed emotions studied (e.g., happy-sad, fearful-happy, positive-negative). The meta-analysis using a random-effects model revealed a moderate to high effect size for the elicitation of mixed emotions (dIG+ = 0.77), which remained consistent regardless of the structure of the affect model, and across different types of mixed emotions. Several methodological and design moderators were tested. Studies using the minimum index (i.e., the minimum value between a pair of opposite valenced affects) resulted in smaller effect sizes, whereas subjective measures of mixed emotions increased the effect sizes. The presence of more women in the samples was also associated with larger effect sizes. The current study indicates that mixed emotions are a robust, measurable and non-artifactual experience. The results are discussed in terms of the implications for an affect system that has greater versatility and flexibility than previously thought. PMID:25926805

Maximum size-density relationships for mixed-hardwood forest stands in New England

Treesearch

Dale S. Solomon; Lianjun Zhang

2000-01-01

Maximum size-density relationships were investigated for two mixed-hardwood ecological types (sugar maple-ash and beech-red maple) in New England. Plots meeting type criteria and undergoing self-thinning were selected for each habitat. Using reduced major axis regression, no differences were found between the two ecological types. Pure species plots (the species basal...

Anisotropic Magnus Force in Type-II Superconductors with Planar Defects

NASA Astrophysics Data System (ADS)

Monroy, Ricardo Vega; Gomez, Eliceo Cortés

2015-02-01

The effect of planar defects on the Magnus force in type-II superconductors is studied. It is shown that the deformation of the vortex due to the presence of a planar defect leads to a local decrease in the mean free path of electrons in the vortex. This effect reduces the effective Magnus coefficient in normal direction to the planar defect, leading to an anisotropic regime of the Hall effect. The presented developments here can qualitatively explain experimental observations of the anisotropic Hall effect in high- T c superconductors in the mixed state.

Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

PubMed Central

Wooten, Kevin C.; Rose, Robert M.; Ostir, Glenn V.; Calhoun, William J.; Ameredes, Bill T.; Brasier, Allan R.

2014-01-01

A case report illustrates how multidisciplinary translational teams can be assessed using outcome, process, and developmental types of evaluation using a mixed methods approach. Types of evaluation appropriate for teams are considered in relation to relevant research questions and assessment methods. Logic models are applied to scientific projects and team development to inform choices between methods within a mixed methods design. Use of an expert panel is reviewed, culminating in consensus ratings of 11 multidisciplinary teams and a final evaluation within a team type taxonomy. Based on team maturation and scientific progress, teams were designated as: a) early in development, b) traditional, c) process focused, or d) exemplary. Lessons learned from data reduction, use of mixed methods, and use of expert panels are explored. PMID:24064432

Is There a Relationship between Brain Type, Sex and Motivation to Learn Science?

ERIC Educational Resources Information Center

Zeyer, Albert; Wolf, Sarah

2010-01-01

Whilst sex is considered to be one of the most significant factors influencing attitudes towards science, previous research seems to suggest that, at least in non-science classes, there is no correlation between sex and motivation to learn science. The present study investigates a mixed group of science and non-science students of upper secondary…

Cultural Factors Impacting Student Motivation at a Health Sciences College in the Eastern Province of Saudi Arabia

ERIC Educational Resources Information Center

Abdul Razzak, Nina Lutfi

2016-01-01

This paper presents a reflection on students' levels and types of motivation at a college of health sciences in Saudi Arabia and highlights the social and cultural factors possibly contributing to the differences in motivation among those students. The results of this study, which followed a mixed-methods approach, indicate a multiplicity of…

Randomized clinical trial of encapsulated and hand-mixed glass-ionomer ART restorations: one-year follow-up.

PubMed

Freitas, Maria Cristina Carvalho de Almendra; Fagundes, Ticiane Cestari; Modena, Karin Cristina da Silva; Cardia, Guilherme Saintive; Navarro, Maria Fidela de Lima

2018-01-18

This prospective, randomized, split-mouth clinical trial evaluated the clinical performance of conventional glass ionomer cement (GIC; Riva Self-Cure, SDI), supplied in capsules or in powder/liquid kits and placed in Class I cavities in permanent molars by the Atraumatic Restorative Treatment (ART) approach. A total of 80 restorations were randomly placed in 40 patients aged 11-15 years. Each patient received one restoration with each type of GIC. The restorations were evaluated after periods of 15 days (baseline), 6 months, and 1 year, according to ART criteria. Wilcoxon matched pairs, multivariate logistic regression, and Gehan-Wilcoxon tests were used for statistical analysis. Patients were evaluated after 15 days (n=40), 6 months (n=34), and 1 year (n=29). Encapsulated GICs showed significantly superior clinical performance compared with hand-mixed GICs at baseline (p=0.017), 6 months (p=0.001), and 1 year (p=0.026). For hand-mixed GIC, a statistically significant difference was only observed over the period of baseline to 1 year (p=0.001). Encapsulated GIC presented statistically significant differences for the following periods: 6 months to 1 year (p=0.028) and baseline to 1 year (p=0.002). Encapsulated GIC presented superior cumulative survival rate than hand-mixed GIC over one year. Importantly, both GICs exhibited decreased survival over time. Encapsulated GIC promoted better ART performance, with an annual failure rate of 24%; in contrast, hand-mixed GIC demonstrated a failure rate of 42%.

Numerical simulation of Forchheimer flow to a partially penetrating well with a mixed-type boundary condition

NASA Astrophysics Data System (ADS)

Mathias, Simon A.; Wen, Zhang

2015-05-01

This article presents a numerical study to investigate the combined role of partial well penetration (PWP) and non-Darcy effects concerning the performance of groundwater production wells. A finite difference model is developed in MATLAB to solve the two-dimensional mixed-type boundary value problem associated with flow to a partially penetrating well within a cylindrical confined aquifer. Non-Darcy effects are incorporated using the Forchheimer equation. The model is verified by comparison to results from existing semi-analytical solutions concerning the same problem but assuming Darcy's law. A sensitivity analysis is presented to explore the problem of concern. For constant pressure production, Non-Darcy effects lead to a reduction in production rate, as compared to an equivalent problem solved using Darcy's law. For fully penetrating wells, this reduction in production rate becomes less significant with time. However, for partially penetrating wells, the reduction in production rate persists for much larger times. For constant production rate scenarios, the combined effect of PWP and non-Darcy flow takes the form of a constant additional drawdown term. An approximate solution for this loss term is obtained by performing linear regression on the modeling results.

Photo series for quantifying forest residues in the: sierra mixed conifer type, sierra true fir type.

Treesearch

W.G. Maxwell; F.R. Ward

1979-01-01

Five series of photographs display different forest residue loading levels, by size classes, for areas of like timber type (Sierra mixed conifer and Sierra true fir) and cutting objective. Information with each photo includes measured weights, volumes and other residue data, information about the timber stand and harvest actions, and assessment of fire behavior and...

Using Radar, Lidar, and Radiometer measurements to Classify Cloud Type and Study Middle-Level Cloud Properties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Zhien

2010-06-29

The project is mainly focused on the characterization of cloud macrophysical and microphysical properties, especially for mixed-phased clouds and middle level ice clouds by combining radar, lidar, and radiometer measurements available from the ACRF sites. First, an advanced mixed-phase cloud retrieval algorithm will be developed to cover all mixed-phase clouds observed at the ACRF NSA site. The algorithm will be applied to the ACRF NSA observations to generate a long-term arctic mixed-phase cloud product for model validations and arctic mixed-phase cloud processes studies. To improve the representation of arctic mixed-phase clouds in GCMs, an advanced understanding of mixed-phase cloud processesmore » is needed. By combining retrieved mixed-phase cloud microphysical properties with in situ data and large-scale meteorological data, the project aim to better understand the generations of ice crystals in supercooled water clouds, the maintenance mechanisms of the arctic mixed-phase clouds, and their connections with large-scale dynamics. The project will try to develop a new retrieval algorithm to study more complex mixed-phase clouds observed at the ACRF SGP site. Compared with optically thin ice clouds, optically thick middle level ice clouds are less studied because of limited available tools. The project will develop a new two wavelength radar technique for optically thick ice cloud study at SGP site by combining the MMCR with the W-band radar measurements. With this new algorithm, the SGP site will have a better capability to study all ice clouds. Another area of the proposal is to generate long-term cloud type classification product for the multiple ACRF sites. The cloud type classification product will not only facilitates the generation of the integrated cloud product by applying different retrieval algorithms to different types of clouds operationally, but will also support other research to better understand cloud properties and to validate model simulations. The ultimate goal is to improve our cloud classification algorithm into a VAP.« less

Gamma-based Measurement of ``Dark Mix'' in ICF Capsules

NASA Astrophysics Data System (ADS)

Meaney, Kevin; Herrmann, H.; Kim, Yh; Zylstra, Ab; Geppert-Kleinrath, H.; Hoffman, Nm; Yi, As

2017-10-01

Mix of capsule ablator material into the fusion fuel is a source of yield degradation in inertial confinement fusion. Jetting or chunk mix, such as the elusive ``meteors'' that have been observed at NIF, can be difficult to diagnose because the chunks may not get hot enough to excite dopant x-rays, nor atomized enough for separated-reactants to fuse. Using the gamma reaction history (GRH-6m) diagnostic, (n,n') gammas from strategically placed carbon layer within a beryllium capsule gives a measure of the time-resolved areal density of this carbon during the burn and hence an indication of the compression and spatial distribution of this layer. As the carbon moves further from the fuel, the areal density nominally decreases as 1/r2 for unablated material. However, mix of this carbon into the cold dense fuel layer or hot spot will have a significant effect on the carbon gamma signal. Different types of mix (e.g., jetting, Rayleigh-Taylor fingers, diffusive, ...) as well as features that can seed this mix (eg., tents, fill,...) will be discussed along with their expected effect on the carbon signal. The design for upcoming OMEGA shots, which will demonstrate this technique, and the potential for use on the NIF will be presented.

The Chemical Capacitance as a Fingerprint of Defect Chemistry in Mixed Conducting Oxides.

PubMed

Fleig, Juergen; Schmid, Alexander; Rupp, Ghislain M; Slouka, Christoph; Navickas, Edvinas; Andrejs, Lukas; Hutter, Herbert; Volgger, Lukas; Nenning, Andreas

2016-01-01

The oxygen stoichiometry of mixed conducting oxides depends on the oxygen chemical potential and thus on the oxygen partial pressure in the gas phase. Also voltages may change the local oxygen stoichiometry and the amount to which such changes take place is quantified by the chemical capacitance of the sample. Impedance spectroscopy can be used to probe this chemical capacitance. Impedance measurements on different oxides ((La,Sr)FeO3-δ = LSF, Sr(Ti,Fe)O3-δ = STF, and Pb(Zr,Ti)O3 = PZT) are presented, and demonstrate how the chemical capacitance may affect impedance spectra in different types of electrochemical cells. A quantitative analysis of the spectra is based on generalized equivalent circuits developed for mixed conducting oxides by J. Jamnik and J. Maier. It is discussed how defect chemical information can be deduced from the chemical capacitance.

Numerical Simulations of Two-Phase Reacting Flow in a Single-Element Lean Direct Injection (LDI) Combustor Using NCC

NASA Technical Reports Server (NTRS)

Liu, Nan-Suey; Shih, Tsan-Hsing; Wey, C. Thomas

2011-01-01

A series of numerical simulations of Jet-A spray reacting flow in a single-element lean direct injection (LDI) combustor have been conducted by using the National Combustion Code (NCC). The simulations have been carried out using the time filtered Navier-Stokes (TFNS) approach ranging from the steady Reynolds-averaged Navier-Stokes (RANS), unsteady RANS (URANS), to the dynamic flow structure simulation (DFS). The sub-grid model employed for turbulent mixing and combustion includes the well-mixed model, the linear eddy mixing (LEM) model, and the filtered mass density function (FDF/PDF) model. The starting condition of the injected liquid spray is specified via empirical droplet size correlation, and a five-species single-step global reduced mechanism is employed for fuel chemistry. All the calculations use the same grid whose resolution is of the RANS type. Comparisons of results from various models are presented.

Preparation and photovoltaic properties of CdS quantum dot-sensitized solar cell based on zinc tin mixed metal oxides.

PubMed

Cao, Jiupeng; Zhao, Yifan; Zhu, Yatong; Yang, Xiaoyu; Shi, Peng; Xiao, Hongdi; Du, Na; Hou, Wanguo; Qi, Genggeng; Liu, Jianqiang

2017-07-15

The present study reports a new type of quantum dot sensitized solar cells (QDSSCs) using the zinc tin mixed metal oxides (MMO) as the anode materials, which were obtained from the layered double hydroxide (LDH) precursor. The successive ionic layer adsorption and reaction (SILAR) method is applied to deposit CdS quantum dots. The effects of sensitizing cycles on the performance of CdS QDSSC are studied. Scanning electron microscopy (SEM), Transmission electron microscope (TEM) and X-ray diffraction (XRD) are used to identify the surface profile and crystal structure of the mixed metal oxides anode. The photovoltaic performance of the QDSSC is studied by the electrochemical method. The new CdS QDSSC exhibits power conversion efficiency (PCE) up to 0.48% when the anode was sensitized for eight cycles. Copyright © 2017 Elsevier Inc. All rights reserved.

Analysis of the type II robotic mixed-model assembly line balancing problem

NASA Astrophysics Data System (ADS)

Çil, Zeynel Abidin; Mete, Süleyman; Ağpak, Kürşad

2017-06-01

In recent years, there has been an increasing trend towards using robots in production systems. Robots are used in different areas such as packaging, transportation, loading/unloading and especially assembly lines. One important step in taking advantage of robots on the assembly line is considering them while balancing the line. On the other hand, market conditions have increased the importance of mixed-model assembly lines. Therefore, in this article, the robotic mixed-model assembly line balancing problem is studied. The aim of this study is to develop a new efficient heuristic algorithm based on beam search in order to minimize the sum of cycle times over all models. In addition, mathematical models of the problem are presented for comparison. The proposed heuristic is tested on benchmark problems and compared with the optimal solutions. The results show that the algorithm is very competitive and is a promising tool for further research.

Oxygen diffusion model of the mixed (U,Pu)O2 ± x: Assessment and application

NASA Astrophysics Data System (ADS)

Moore, Emily; Guéneau, Christine; Crocombette, Jean-Paul

2017-03-01

The uranium-plutonium (U,Pu)O2 ± x mixed oxide (MOX) is used as a nuclear fuel in some light water reactors and considered for future reactor generations. To gain insight into fuel restructuring, which occurs during the fuel lifetime as well as possible accident scenarios understanding of the thermodynamic and kinetic behavior is crucial. A comprehensive evaluation of thermo-kinetic properties is incorporated in a computational CALPHAD type model. The present DICTRA based model describes oxygen diffusion across the whole range of plutonium, uranium and oxygen compositions and temperatures by incorporating vacancy and interstitial migration pathways for oxygen. The self and chemical diffusion coefficients are assessed for the binary UO2 ± x and PuO2 - x systems and the description is extended to the ternary mixed oxide (U,Pu)O2 ± x by extrapolation. A simulation to validate the applicability of this model is considered.

Hygroscopic properties of internally mixed particles composed of NaCl and water-soluble organic acids.

PubMed

Ghorai, Suman; Wang, Bingbing; Tivanski, Alexei; Laskin, Alexander

2014-02-18

Atmospheric aging of naturally emitted marine aerosol often leads to formation of internally mixed particles composed of sea salts and water-soluble organic compounds of anthropogenic origin. Mixing of sea salt and organic components has profound effects on the evolving chemical composition and hygroscopic properties of the resulted particles, which are poorly understood. Here, we have studied chemical composition and hygroscopic properties of laboratory generated NaCl particles mixed with malonic acid (MA) and glutaric acid (GA) at different molar ratios using micro-FTIR spectroscopy, atomic force microscopy, and X-ray elemental microanalysis. Hygroscopic properties of internally mixed NaCl and organic acid particles were distinctly different from pure components and varied significantly with the type and amount of organic compound present. Experimental results were in a good agreement with the AIM modeling calculations of gas/liquid/solid partitioning in studied systems. X-ray elemental microanalysis of particles showed that Cl/Na ratio decreased with increasing organic acid component in the particles with MA yielding lower ratios relative to GA. We attribute the depletion of chloride to the formation of sodium malonate and sodium glutarate salts resulted by HCl evaporation from dehydrating particles.

Detailed study of precipitation of a poorly water soluble test compound using methodologies as in activity and solubility screening - mixing and automation effects.

PubMed

Gillespie, Cheska; Kennedy, Alan R; Edwards, Darren; Dowden, Lee; Daublain, Pierre; Halling, Peter

2013-09-01

Storage of pharmaceutical discovery compounds dissolved in dimethylsulfoxide (DMSO) is commonplace within industry. Often, the DMSO stock solution is added to an aqueous system (e.g. in bioassay or kinetic solubility testing)- since most test compounds are hydrophobic, precipitation could occur. Little is known about the factors affecting this precipitation process at the low (µM) concentrations used in screening analyses. Here, a poorly water soluble test compound (tolnaftate) was used to compare manual and automated pipetting, and explore the effect of mixing variables on precipitation. The amount of drug present in the supernatant after precipitation and centrifugation of the samples was quantified. An unusual result was obtained in three different laboratories: results of experiments performed initially were statistically significantly higher than those performed after a few days in the same lab. No significant differences were found between automated and manual pipetting, including in variability. Vortex mixing was found to give significantly lower supernatant amounts compared to milder mixing types. The mixing employed affects the particle growth of the precipitate. These findings are of relevance to discovery stage bioassay and kinetic solubility analyses.

Hygroscopic Properties of Internally Mixed Particles Composed of NaCl and Water-Soluble Organic Acids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghorai, Suman; Wang, Bingbing; Tivanski, Alexei V.

Atmospheric aging of naturally emitted marine aerosol often leads to formation of internally mixed particles composed of sea salts and water soluble organic compounds of anthropogenic origin. Mixing of sea salt and organic components has profound effects on the evolving chemical composition and hygroscopic properties of the resulted particles, which are poorly understood. Here, we have studied chemical composition and hygroscopic properties of laboratory generated NaCl particles mixed with malonic acid (MA) and glutaric acid (GA) at different molar ratios using micro-FTIR spectroscopy and X-ray elemental microanalysis.Hygroscopic properties of inte rnally mixed NaCl and organic acid particles were distinctly differentmore » from pure components and varied significantly with the type and amount of organic compound present. Experimental results were in a good agreement with the AIM modeling calculations of gas/liquid/solid partitioning in studied systems. X-ray elemental microanalysis of particles showed that Cl/Na ratio decreased with increasing organic acid component in the particles with MA yielding lower ratios relative to GA. We attribute the depletion of chloride to the formation of Na-malonate and Na-glutarate salts resulted by HCl evaporation from dehydrating particles.« less

Engineering development and demonstration of DETOX{sup SM} wet oxidation for mixed waste treatment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dhooge, P.M.; Goldblatt, S.D.; Moslander, J.E.

1997-12-01

DETOX{sup SM}, a catalyzed chemical oxidation process, is under development for treatment of hazardous and mixed wastes at Department of Energy sites. To support this effort, developmental engineering studies have been formed for aspects of the process to help ensure safe and effective operation. Subscale agitation studies have been preformed to identify a suitable mixing head and speed for the primary reaction vessel agitator. Mechanisms for feeding solid waste materials to the primary reaction vessel have been investigated. Filtration to remove solid field process residue, and the use of various filtration aids, has been studied. Extended compatibility studies on themore » materials of construction have been performed. Due to a change to Rocky Flats Environmental Technology Site (RFETS) for the mixed waste portion of the demonstration, types of wastes suitable and appropriate for treatment at RFETS had to be chosen. A Prototype unit has been fabricated and will be demonstrated on hazardous and mixed wastes at Savannah River Site (SRS) and RFETS during 1997 and 1998. The unit is in shakedown testing at present. Data validation and an engineering evaluation will be performed during the demonstration.« less

Modal interactions between a large-wavelength inclined interface and small-wavelength multimode perturbations in a Richtmyer-Meshkov instability

NASA Astrophysics Data System (ADS)

McFarland, Jacob A.; Reilly, David; Black, Wolfgang; Greenough, Jeffrey A.; Ranjan, Devesh

2015-07-01

The interaction of a small-wavelength multimodal perturbation with a large-wavelength inclined interface perturbation is investigated for the reshocked Richtmyer-Meshkov instability using three-dimensional simulations. The ares code, developed at Lawrence Livermore National Laboratory, was used for these simulations and a detailed comparison of simulation results and experiments performed at the Georgia Tech Shock Tube facility is presented first for code validation. Simulation results are presented for four cases that vary in large-wavelength perturbation amplitude and the presence of secondary small-wavelength multimode perturbations. Previously developed measures of mixing and turbulence quantities are presented that highlight the large variation in perturbation length scales created by the inclined interface and the multimode complex perturbation. Measures are developed for entrainment, and turbulence anisotropy that help to identify the effects of and competition between each perturbations type. It is shown through multiple measures that before reshock the flow processes a distinct memory of the initial conditions that is present in both large-scale-driven entrainment measures and small-scale-driven mixing measures. After reshock the flow develops to a turbulentlike state that retains a memory of high-amplitude but not low-amplitude large-wavelength perturbations. It is also shown that the high-amplitude large-wavelength perturbation is capable of producing small-scale mixing and turbulent features similar to the small-wavelength multimode perturbations.

Mouse Mix gene is activated early during differentiation of ES and F9 stem cells and induces endoderm in frog embryos.

PubMed

Mohn, Deanna; Chen, Siming W; Dias, Dora Campos; Weinstein, Daniel C; Dyer, Michael A; Sahr, Kenneth; Ducker, Charles E; Zahradka, Elizabeth; Keller, Gordon; Zaret, Kenneth S; Gudas, Lorraine J; Baron, Margaret H

2003-03-01

In frog and zebrafish, the Mix/Bix family of paired type homeodomain proteins play key roles in specification and differentiation of mesendoderm. However, in mouse, only a single Mix gene (mMix) has been identified to date and its function is unknown. We have analyzed the expression of mouse Mix RNA and protein in embryos, embryoid bodies formed from embryonic stem cells and F9 teratocarcinoma cells, as well as several differentiated cell types. Expression in embryoid bodies in culture mirrors that in embryos, where Mix is transcribed transiently in primitive (visceral) endoderm (VE) and in nascent mesoderm. In F9 cells induced by retinoic acid to differentiate to VE, mMix is coordinately expressed with three other endodermal transcription factors, well before AFP, and its protein product is localized to the nucleus. In a subpopulation of nascent mesodermal cells from embryonic stem cell embryoid bodies, mMix is coexpressed with Brachyury. Intriguingly, mMix mRNA is detected in a population (T+Flk1+) of cells which may contain hemangioblasts, before the onset of hematopoiesis and activation of hematopoietic markers. In vitro and in vivo, mMix expression in nascent mesoderm is rapidly down-regulated and becomes undetectable in differentiated cell types. In the region of the developing gut, mMix expression is confined to the mesoderm of mid- and hindgut but is absent from definitive endoderm. Injection of mouse mMix RNA into early frog embryos results in axial truncation of developing tadpoles and, in animal cap assays, mMix alone is sufficient to activate expression of several endodermal (but not mesodermal) markers. Although these observations do not exclude a possible cell-autonomous function for mMix in mesendodermal progenitor cells, they do suggest an additional, non-cell autonomous role in nascent mesoderm in the formation and/or patterning of adjacent definitive endoderm. Copyright 2003 Wiley-Liss, Inc.

Improving the mixing performance of side channel type micromixers using an optimal voltage control model.

PubMed

Wu, Chien-Hsien; Yang, Ruey-Jen

2006-06-01

Electroosmotic flow in microchannels is restricted to low Reynolds number regimes. Since the inertia forces are extremely weak in such regimes, turbulent conditions do not readily develop, and hence species mixing occurs primarily as a result of diffusion. Consequently, achieving a thorough species mixing generally relies upon the use of extended mixing channels. This paper aims to improve the mixing performance of conventional side channel type micromixers by specifying the optimal driving voltages to be applied to each channel. In the proposed approach, the driving voltages are identified by constructing a simple theoretical scheme based on a 'flow-rate-ratio' model and Kirchhoff's law. The numerical and experimental results confirm that the optimal voltage control approach provides a better mixing performance than the use of a single driving voltage gradient.

Probing the Evaporation Dynamics of Mixed SOA/Squalane Particles Using Size-Resolved Composition and Single-Particle Measurements.

PubMed

Robinson, Ellis Shipley; Saleh, Rawad; Donahue, Neil M

2015-08-18

An analysis of the formation and evaporation of mixed-particles containing squalane (a surrogate for hydrophobic primary organic aerosol, POA) and secondary organic aerosol (SOA) is presented. In these experiments, one material (D62-squalane or SOA from α-pinene + O3) was prepared first to serve as surface area for condensation of the other, forming the mixed-particles. The mixed-particles were then subjected to a heating-ramp from 22 to 44 °C. We were able to determine that (1) almost all of the SOA mass is comprised of material less volatile than D62-squalane; (2) AMS collection efficiency in these mixed-particle systems can be parametrized as a function of the relative mass fraction of the components; and (3) the vast majority of D62-squalane is able to evaporate from the mixed particles, and does so on the same time scale regardless of the order of preparation. We also performed two-population mixing experiments to directly test whether D62-squalane and SOA from α-pinene + O3 form a single solution or two separate phases. We find that these two OA types are immiscible, which informs our inference of the morphology of the mixed-particles. If the morphology is core-shell and dictated by the order of preparation, these data indicate that squalane is able to diffuse relatively quickly through the SOA shell, implying that there are no major diffusion limitations.

Pneumocystis jiroveci in Portuguese immunocompromised patients: association of specific ITS genotypes with treatment failure, bad clinical outcome and childhood.

PubMed

Matos, Olga; Lee, Chao-Hung; Jin, Shaoling; Li, Baozheng; Costa, Marina C; Gonçalves, Luzia; Antunes, Francisco

2003-11-01

We analyzed the genetic variation among isolates of Pneumocystis jiroveci from Portuguese immunocompromised patients with PCP at the internal transcribed spacer (ITS) regions of the nuclear rRNA operon and at the dihydropteroate synthase (DHPS) gene. Pulmonary secretions from 42 patients with PCP corresponding to 43 episodes were studied. Demographic, immunological, and clinical data were obtained from all patients. By combining the two regions ITS1 and ITS2, we found 17 different ITS types of P. jiroveci, two of them were new types (Pb and Pe). The four most prevalent ITS types were Eg (23.3%), Eb and Ne (11.6% each), and Bi (9.3%). A single type was detected in 95.3% of the samples and 4.7% had mixed infections with three different ITS types. DHPS mutants were present in 17 (46%), and the wildtype was present in 20 (54%) of 37 isolates. No association was found between ITS and DHPS types and between DHPS types and therapy or response to anti-PCP treatment. Type Ne presented an association with negative response to anti-PCP treatment (P<0.001) and with death before 120 days after PCP diagnosis (P=0.025). Type Eb was significantly more common in children than in adults (P=0.001). Our data suggest an association of specific ITS genotypes with treatment failure, bad clinical outcome and childhood.

Double bubble with the big-bubble technique during deep anterior lamellar keratoplasty.

PubMed

Wise, Stephanie; Dubord, Paul; Yeung, Sonia N

2017-04-28

To report a case of intraoperative double bubble that formed during big-bubble DALK surgery in a patient with corneal scarring secondary to herpetic stromal keratitis. Case report. A 22 year old woman presented with a large corneal scar, likely secondary to previous herpetic stromal keratitis. She underwent big-bubble DALK surgery for visual rehabilitation. Intraoperatively, a mixed bubble with persistent type 2 bubble postoperatively was noted. The second bubble resorbed with clearance of the graft and good visual outcome after 6 weeks. This case report describes the unusual development of a mixed bubble during big-bubble DALK surgery. This graft cleared with resolution of the second bubble postoperatively without further surgical intervention.

Wave-mixing-induced transparency with zero phase shift in atomic vapors

NASA Astrophysics Data System (ADS)

Zhou, F.; Zhu, C. J.; Li, Y.

2017-12-01

We present a wave-mixing induced transparency that can lead to a hyper-Raman gain-clamping effect. This new type of transparency is originated from a dynamic gain cancellation effect in a multiphoton process where a highly efficient light field of new frequency is generated and amplified. We further show that this novel dynamic gain cancellation effect not only makes the medium transparent to a probe light field at appropriate frequency but also eliminates the probe field propagation phase shift. This gain-cancellation-based induced transparency holds for many potential applications on optical communication and may lead to effective suppression of parasitic Raman/hyper-Raman noise field generated in high intensity optical fiber transmissions.

Error analysis of multipoint flux domain decomposition methods for evolutionary diffusion problems

NASA Astrophysics Data System (ADS)

Arrarás, A.; Portero, L.; Yotov, I.

2014-01-01

We study space and time discretizations for mixed formulations of parabolic problems. The spatial approximation is based on the multipoint flux mixed finite element method, which reduces to an efficient cell-centered pressure system on general grids, including triangles, quadrilaterals, tetrahedra, and hexahedra. The time integration is performed by using a domain decomposition time-splitting technique combined with multiterm fractional step diagonally implicit Runge-Kutta methods. The resulting scheme is unconditionally stable and computationally efficient, as it reduces the global system to a collection of uncoupled subdomain problems that can be solved in parallel without the need for Schwarz-type iteration. Convergence analysis for both the semidiscrete and fully discrete schemes is presented.

A comparative study of several compressibility corrections to turbulence models applied to high-speed shear layers

NASA Technical Reports Server (NTRS)

Viegas, John R.; Rubesin, Morris W.

1991-01-01

Several recently published compressibility corrections to the standard k-epsilon turbulence model are used with the Navier-Stokes equations to compute the mixing region of a large variety of high speed flows. These corrections, specifically developed to address the weakness of higher order turbulence models to accurately predict the spread rate of compressible free shear flows, are applied to two stream flows of the same gas mixing under a large variety of free stream conditions. Results are presented for two types of flows: unconfined streams with either (1) matched total temperatures and static pressures, or (2) matched static temperatures and pressures, and a confined stream.

Composition of the Home Care Service Package: Predictors of Type, Volume, and Mix of Services Provided to Poor and Frail Older People.

ERIC Educational Resources Information Center

Diwan, Sadhna; And Others

1997-01-01

Examined type of service, volume, and mix of services provided to 270 poor and frail elders. Predictors of use and volume of service differed depending on type of service. The most prescribed service combinations included nursing, home health, and homemaker; homemaker only; nursing and home health; nursing and homemaker; and nurse only. (RJM)

Do case-mix adjusted nursing home reimbursements actually reflect costs? Minnesota's experience.

PubMed

Nyman, J A; Connor, R A

1994-07-01

Some states have adopted Medicaid reimbursement systems that pay nursing homes according to patient type. These case-mix adjusted reimbursements are intended in part to eliminate the incentive in prospective systems to exclude less profitable patients. This study estimates the marginal costs of different patient types under Minnesota's case-mix system and compares them to their corresponding reimbursements. We find that estimated costs do not match reimbursement rates, again making some patient types less profitable than others. Further, in confirmation of our estimates, we find that the percentage change in patient days between 1986 and 1990 is explained by our profitability estimates.

Foundations of chaotic mixing.

PubMed

Wiggins, Stephen; Ottino, Julio M

2004-05-15

The simplest mixing problem corresponds to the mixing of a fluid with itself; this case provides a foundation on which the subject rests. The objective here is to study mixing independently of the mechanisms used to create the motion and review elements of theory focusing mostly on mathematical foundations and minimal models. The flows under consideration will be of two types: two-dimensional (2D) 'blinking flows', or three-dimensional (3D) duct flows. Given that mixing in continuous 3D duct flows depends critically on cross-sectional mixing, and that many microfluidic applications involve continuous flows, we focus on the essential aspects of mixing in 2D flows, as they provide a foundation from which to base our understanding of more complex cases. The baker's transformation is taken as the centrepiece for describing the dynamical systems framework. In particular, a hierarchy of characterizations of mixing exist, Bernoulli --> mixing --> ergodic, ordered according to the quality of mixing (the strongest first). Most importantly for the design process, we show how the so-called linked twist maps function as a minimal picture of mixing, provide a mathematical structure for understanding the type of 2D flows that arise in many micromixers already built, and give conditions guaranteeing the best quality mixing. Extensions of these concepts lead to first-principle-based designs without resorting to lengthy computations.

7 CFR 51.2112 - Mixed varieties.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed varieties. 51.2112 Section 51.2112 Agriculture..., CERTIFICATION, AND STANDARDS) United States Standards for Grades of Shelled Almonds Mixed Varieties § 51.2112 Mixed varieties. Any lot of shelled almonds designated as “one type” or undesignated as to type, which...

7 CFR 51.2112 - Mixed varieties.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed varieties. 51.2112 Section 51.2112 Agriculture..., CERTIFICATION, AND STANDARDS) United States Standards for Grades of Shelled Almonds Mixed Varieties § 51.2112 Mixed varieties. Any lot of shelled almonds designated as “one type” or undesignated as to type, which...

Experimental evaluation of high performance base course and road base asphalt concrete with electric arc furnace steel slags.

PubMed

Pasetto, Marco; Baldo, Nicola

2010-09-15

The paper presents the results of a laboratory study aimed at verifying the use of two types of electric arc furnace (EAF) steel slags as substitutes for natural aggregates, in the composition of base course and road base asphalt concrete (BBAC) for flexible pavements. The trial was composed of a preliminary study of the chemical, physical, mechanical and leaching properties of the EAF steel slags, followed by the mix design and performance characterization of the bituminous mixes, through gyratory compaction tests, permanent deformation tests, stiffness modulus tests at various temperatures, fatigue tests and indirect tensile strength tests. All the mixtures with EAF slags presented better mechanical characteristics than those of the corresponding asphalts with natural aggregate and satisfied the requisites for acceptance in the Italian road sector technical standards, thus resulting as suitable for use in road construction. Copyright 2010 Elsevier B.V. All rights reserved.

A new modified tandem appliance for management of developing Class III malocclusion.

PubMed

Sukh, Ram; Singh, Gyan P; Tandon, Pradeep

2013-10-01

Most developing Class III patients display a retruded maxilla. Early intervention in mixed dentition is associated with better patient compliance and possibly a better orthopedic response, which can produce favorable results. The aim of this article is to present the fabrication of the new modified tandem appliance and its use in management of developing Class III malocclusion. The therapeutic results of a new modified tandem appliance are presented in an 8 year-old male patient with anterior cross bite and retrognathic maxilla at the mixed dentition stage. Anterior cross bite was corrected in 3 months and the positive overjet of 4 mm after continued use of the appliance for 1 year. There was a significant improvement in profile of the patient. The use of this appliance in this type of malocclusion enabled the correction of malocclusion in a few months and encouraging favorable skeletal growth in the future.

Phylobetadiversity among forest types in the Brazilian Atlantic Forest complex.

PubMed

Duarte, Leandro Da Silva; Bergamin, Rodrigo Scarton; Marcilio-Silva, Vinícius; Seger, Guilherme Dubal Dos Santos; Marques, Márcia Cristina Mendes

2014-01-01

Phylobetadiversity is defined as the phylogenetic resemblance between communities or biomes. Analyzing phylobetadiversity patterns among different vegetation physiognomies within a single biome is crucial to understand the historical affinities between them. Based on the widely accepted idea that different forest physiognomies within the Southern Brazilian Atlantic Forest constitute different facies of a single biome, we hypothesize that more recent phylogenetic nodes should drive phylobetadiversity gradients between the different forest types within the Atlantic Forest, as the phylogenetic divergence among those forest types is biogeographically recent. We compiled information from 206 checklists describing the occurrence of shrub/tree species across three different forest physiognomies within the Southern Brazilian Atlantic Forest (Dense, Mixed and Seasonal forests). We analyzed intra-site phylogenetic structure (phylogenetic diversity, net relatedness index and nearest taxon index) and phylobetadiversity between plots located at different forest types, using five different methods differing in sensitivity to either basal or terminal nodes (phylogenetic fuzzy weighting, COMDIST, COMDISTNT, UniFrac and Rao's H). Mixed forests showed higher phylogenetic diversity and overdispersion than the other forest types. Furthermore, all forest types differed from each other in relation phylobetadiversity patterns, particularly when phylobetadiversity methods more sensitive to terminal nodes were employed. Mixed forests tended to show higher phylogenetic differentiation to Dense and Seasonal forests than these latter from each other. The higher phylogenetic diversity and phylobetadiversity levels found in Mixed forests when compared to the others likely result from the biogeographical origin of several taxa occurring in these forests. On one hand, Mixed forests shelter several temperate taxa, like the conifers Araucaria and Podocarpus. On the other hand, tropical groups, like Myrtaceae, are also very representative of this forest type. We point out to the need of more attention to Mixed forests as a conservation target within the Brazilian Atlantic Forest given their high phylogenetic uniqueness.

Phylobetadiversity among Forest Types in the Brazilian Atlantic Forest Complex

PubMed Central

Duarte, Leandro Da Silva; Bergamin, Rodrigo Scarton; Marcilio-Silva, Vinícius; Seger, Guilherme Dubal Dos Santos; Marques, Márcia Cristina Mendes

2014-01-01

Phylobetadiversity is defined as the phylogenetic resemblance between communities or biomes. Analyzing phylobetadiversity patterns among different vegetation physiognomies within a single biome is crucial to understand the historical affinities between them. Based on the widely accepted idea that different forest physiognomies within the Southern Brazilian Atlantic Forest constitute different facies of a single biome, we hypothesize that more recent phylogenetic nodes should drive phylobetadiversity gradients between the different forest types within the Atlantic Forest, as the phylogenetic divergence among those forest types is biogeographically recent. We compiled information from 206 checklists describing the occurrence of shrub/tree species across three different forest physiognomies within the Southern Brazilian Atlantic Forest (Dense, Mixed and Seasonal forests). We analyzed intra-site phylogenetic structure (phylogenetic diversity, net relatedness index and nearest taxon index) and phylobetadiversity between plots located at different forest types, using five different methods differing in sensitivity to either basal or terminal nodes (phylogenetic fuzzy weighting, COMDIST, COMDISTNT, UniFrac and Rao’s H). Mixed forests showed higher phylogenetic diversity and overdispersion than the other forest types. Furthermore, all forest types differed from each other in relation phylobetadiversity patterns, particularly when phylobetadiversity methods more sensitive to terminal nodes were employed. Mixed forests tended to show higher phylogenetic differentiation to Dense and Seasonal forests than these latter from each other. The higher phylogenetic diversity and phylobetadiversity levels found in Mixed forests when compared to the others likely result from the biogeographical origin of several taxa occurring in these forests. On one hand, Mixed forests shelter several temperate taxa, like the conifers Araucaria and Podocarpus. On the other hand, tropical groups, like Myrtaceae, are also very representative of this forest type. We point out to the need of more attention to Mixed forests as a conservation target within the Brazilian Atlantic Forest given their high phylogenetic uniqueness. PMID:25121495

An unusual case of anaphylaxis. Mold in pancake mix.

PubMed

Bennett, A T; Collins, K A

2001-09-01

Anaphylactic reactions involve contact with an antigen that evokes an immune reaction that is harmful. This type of reaction is a rapidly developing immunologic reaction termed a type I hypersensitivity reaction. The antigen complexes with an IgE antibody that is bound to mast cells and basophils in a previously sensitized individual. Upon re-exposure, vasoactive and spasmogenic substances are released that act on vessels and smooth muscle. The reaction can be local or systemic and may be fatal. The authors report the death of a 19-year-old white male who had a history of "multiple allergies," including pets, molds, and penicillin. One morning, he and his friends made pancakes with a packaged mix that had been opened and in the cabinet for approximately 2 years. The friends stopped eating the pancakes because they said that they tasted like "rubbing alcohol." The decedent continued to eat the pancakes and suddenly became short of breath. He was taken to a nearby clinic, where he became unresponsive and died. At autopsy, laryngeal edema and hyperinflated lungs with mucous plugging were identified. Microscopically, edema and numerous degranulating mast cells were identified in the larynx. The smaller airways contained mucus, and findings of chronic asthma were noted. Serum tryptase was elevated at 14.0 ng/ml. The pancake mix was analyzed and found to contain a total mold count of 700/g of mix as follows: Penicillium, Fusarium, Mucor, and Aspergillus. Witness statements indicate that the decedent ate two pancakes; thus he consumed an approximate mold count of 21,000. The decedent had a history of allergies to molds and penicillin, and thus was allergic to the molds in the pancake mix. The authors present this unusual case of anaphylaxis and a review of the literature.

Mixed Calcium Dust and Carbonaceous Particles from Asia Contributing to Precipitation Changes in California

NASA Astrophysics Data System (ADS)

Kristensen, L.; Cornwell, G.; Sedlacek, A. J., III; Prather, K. A.

2016-12-01

Mineral dust particles can serve as cloud condensation nuclei (CCN), with enhanced CCN activity observed when the dust is mixed with additional soluble species. Long range atmospheric transport can change the composition of dust particles through aging, cloud processing and mixing with other particles. The CalWater2 campaign measured single particles and cloud dynamics to investigate the influence aerosols have on the hydrological cycle in California. An Aircraft Aerosol Time-of-Flight Mass Spectrometer (ATOFMS) was used to characterize and identify single particles within clouds potentially acting as ice and cloud nuclei. Two matching flights over California's mountains in March 2015 detected significantly different particle types that resulted in different precipitation totals. Calcium dust dominated the particle composition during the first flight which had an observed decrease in orographic precipitation. Particle composition and air mass back trajectories indicate an Asian desert origin. The calcium dust particles contained secondary acids, in particular oxalic acid, acquired during transport from Asia to California. This chemical processing likely increased the solubility of the dust, enabling the particles to act as more effective CCN. The chemical composition also showed oligomeric carbonaceous species were mixed with the calcium dust particles, potentially further increasing the solubility the particles. A single particle soot photometer (SP2) measured black carbon concurrently and returned intense incandescence when calcium dust was present, confirming the calcium dust particles were internally mixed with a carbonaceous species. Dust particles were greatly reduced during the second flight with local biomass burning particles the dominant type. Observed precipitation in California were within forecast levels during the second flight. These single particle measurements from CalWater2 show that dust particles from Asia can affect cloud process and thus precipitation in California.

Emissions Associated with Electric Vehicle Charging: Impact of Electricity Generation Mix, Charging Infrastructure Availability, and Vehicle Type

DOE Office of Scientific and Technical Information (OSTI.GOV)

McLaren, Joyce; Miller, John; O'Shaughnessy, Eric

With the aim of reducing greenhouse gas emissions associated with the transportation sector, policy-makers are supporting a multitude of measures to increase electric vehicle adoption. The actual level of emission reduction associated with the electrification of the transport sector is dependent on the contexts that determine when and where drivers charge electric vehicles. This analysis contributes to our understanding of the degree to which a particular electricity grid profile, vehicle type, and charging patterns impact CO2 emissions from light-duty, plug-in electric vehicles. We present an analysis of emissions resulting from both battery electric and plug-in hybrid electric vehicles for fourmore » charging scenarios and five electricity grid profiles. A scenario that allows drivers to charge electric vehicles at the workplace yields the lowest level of emissions for the majority of electricity grid profiles. However, vehicle emissions are shown to be highly dependent on the percentage of fossil fuels in the grid mix, with different vehicle types and charging scenarios resulting in fewer emissions when the carbon intensity of the grid is above a defined level. Restricting charging to off-peak hours results in higher total emissions for all vehicle types, as compared to other charging scenarios.« less

A Gas-Kinetic Method for Hyperbolic-Elliptic Equations and Its Application in Two-Phase Fluid Flow

NASA Technical Reports Server (NTRS)

Xu, Kun

1999-01-01

A gas-kinetic method for the hyperbolic-elliptic equations is presented in this paper. In the mixed type system, the co-existence and the phase transition between liquid and gas are described by the van der Waals-type equation of state (EOS). Due to the unstable mechanism for a fluid in the elliptic region, interface between the liquid and gas can be kept sharp through the condensation and evaporation process to remove the "averaged" numerical fluid away from the elliptic region, and the interface thickness depends on the numerical diffusion and stiffness of the phase change. A few examples are presented in this paper for both phase transition and multifluid interface problems.

Comparison of insulin lispro mix 25 with insulin lispro mix 50 as insulin starter in Chinese patients with type 2 diabetes mellitus (CLASSIFY study): Subgroup analysis of a Phase 4 open-label randomized trial.

PubMed

Su, Qing; Liu, Chao; Zheng, Hongting; Zhu, Jun; Li, Peng Fei; Qian, Lei; Yang, Wen Ying

2017-06-01

Premixed insulins are recommended starter insulins in Chinese patients after oral antihyperglycemic medication (OAM) failure. In the present study, we compared the efficacy and safety of insulin lispro mix 25 (LM25) twice daily (b.i.d.) and insulin lispro mix 50 (LM50) b.i.d. as a starter insulin regimen in Chinese patients with type 2 diabetes mellitus (T2DM) who had inadequate glycemic control with OAMs. The primary efficacy outcome in the present open-label parallel randomized clinical trial was change in HbA1c from baseline to 26 weeks. Patients were randomized in a ratio of 1:  1 to LM25 (n = 80) or LM50 (n = 76). A mixed-effects model with repeated measures was used to analyze continuous variables. The Cochran-Mantel-Haenszel test with stratification factor was used to analyze categorical variables. At the end of the study, LM50 was more efficacious than LM25 in reducing mean HbA1c levels (least-squares [LS] mean difference 0.48; 95 % confidence interval [CI] 0.22, 0.74; P < 0.001). More subjects in the LM50 than LM25 group achieved HbA1c targets of <7.0 % (72.4 % vs 45.0 %; P = 0.001) or ≤6.5 % (52.6 % vs 20.0 %; P < 0.001). Furthermore, LM50 was more effective than LM25 at reducing HbA1c in patients with baseline HbA1c, blood glucose excursion, and postprandial glucose greater than or equal to median levels (P ≤ 0.001). The rate and incidence of hypoglycemic episodes and increase in weight at the end of the study were similar between treatment groups. In Chinese patients with T2DM, LM50 was more efficacious than LM25 as a starter insulin. © 2016 The Authors. Journal of Diabetes published by John Wiley & Sons Australia, Ltd and Ruijin Hospital, Shanghai Jiaotong University School of Medicine.

Questionnaire and behavioral task measures of impulsivity are differentially associated with body mass index: A comprehensive meta-analysis.

PubMed

Emery, Rebecca L; Levine, Michele D

2017-08-01

Although impulsivity has been implicated in the development and maintenance of obesity, evidence linking impulsivity to obesity has been mixed. These mixed findings may be related to differences in the type of impulsivity measures used and the varied domains of impulsivity assessed by each measure. The present meta-analysis aimed to examine the impact of measurement selection on the relationship between impulsivity and body mass index (BMI). A total of 142 articles met inclusion criteria and were comprised of 315,818 participants. Effect sizes consisted of Fisher's z-transformed correlation coefficients, which were weighted by the inverse variance to establish the grand mean estimate of the relationship between impulsivity and BMI. Overall weighted mean effect sizes also were computed for each type and domain of impulsivity measure. Moderator analyses were conducted using a mixed-effects approach to determine if the relationship between impulsivity and BMI varied between the types of impulsivity measures used. On average, participants were 32.25 (SD = 12.41) years of age, with a BMI of 26.63 (SD = 5.73) kg/m2. The overall relationship between impulsivity and BMI was small but significant (r = .07). Behavioral task measures of impulsivity produced significantly larger effect sizes (r = .10) than did questionnaire measures of impulsivity (r = .05). Domains of impulsivity that assessed disinhibited behaviors (r = .10), attentional deficits (r = .11), impulsive decision-making (r = .10), and cognitive inflexibility (r = .17) produced significant effect sizes. These meta-analytic findings demonstrate that impulsivity is positively associated with BMI and further document that this association varies by the type of impulsivity measure used and the domain of impulsivity assessed. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Immunolocalization of clavanins in Styela clava hemocytes.

PubMed

Menzel, Lorenzo P; Lee, In Hee; Sjostrand, Birgitta; Lehrer, Robert I

2002-07-01

Antimicrobial peptides play an important role in innate host defenses against infection. Clavanins are histidine-rich, amidated, 23-residue alpha-helical antimicrobial peptides that were isolated from a mixed population of Styela clava hemocytes. To learn which types of hemocytes contained clavanins, we raised a polyclonal antibody that recognized five different clavanins, and used it to localize these peptides by light and electron microscopy. Clavanins were present in the cytoplasmic granules and/or cytoplasm of five different types of granulocytes and they also occurred throughout the cytoplasm of macrophages. The orange G component of Mallory's trichrome stain had a high affinity for clavanins, and for the cytoplasmic granules of S. clava's hemocytes. Semiquantitative analysis of acid urea-PAGE gels suggested that clavanins and styelins comprised between 10 and 20% of the total cellular protein of eosinophilic granulocytes. Orange G and the century-old trichrome stain may provide simple screening tools for identifying cells that contain large amounts of antimicrobial peptides in mixed hemocyte populations.

The use of food waste-based diets and Napier grass to culture grass carp: growth performance and contaminants contained in cultured fish.

PubMed

Cheng, Zhang; Mo, Wing-Yin; Nie, Xiang-Ping; Li, Kai-Bing; Choi, Wai-Ming; Man, Yu-Bon; Wong, Ming-Hung

2016-04-01

The present study used commercial feeds, food waste feeds, Napier grass, and mixed feeds (food waste feed to Napier grass ratio, 1:10) to feed grass carp (Ctenopharyngodon idellus). The results indicated that grass carp fed with food waste feeds and mix feeds achieved growth performance (based on specific growth rate and feed conversion ratio) that was similar to commercial feeds (p > 0.05). Concentrations of metalloid/metals in food waste feeds and polycyclic aromatic hydrocarbons (PAHs) in Napier grass were relatively higher than other types of fish feeds (p < 0.05). However, most of the metalloid/metals and PAH levels in fish fed with four types of fish feeds were not significantly different (p > 0.05). These findings show that food waste feeds are suitable for using in the production of fish feed and Napier grass can be served as supplemental feeds for grass carp, and hence reducing the production cost.

CAN STELLAR MIXING EXPLAIN THE LACK OF TYPE Ib SUPERNOVAE IN LONG-DURATION GAMMA-RAY BURSTS?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frey, Lucille H.; Fryer, Chris L.; Young, Patrick A.

2013-08-10

The discovery of supernovae associated with long-duration gamma-ray burst observations is primary evidence that the progenitors of these outbursts are massive stars. One of the principle mysteries in understanding these progenitors has been the fact that all of these gamma-ray-burst-associated supernovae are Type Ic supernovae with no evidence of helium in the stellar atmosphere. Many studies have focused on whether or not this helium is simply hidden from spectral analyses. In this Letter, we show results from recent stellar models using new convection algorithms based on our current understanding of stellar mixing. We demonstrate that enhanced convection may lead tomore » severe depletion of stellar helium layers, suggesting that the helium is not observed simply because it is not in the star. We also present light curves and spectra of these compact helium-depleted stars compared to models with more conventional helium layers.« less

Data Mining and Homeland Security: An Overview

DTIC Science & Technology

2006-01-27

which government agencies should use and mix commercial data with government data, whether data sources are being used for purposes other than those...example, a hardware store may compare their customers’ tool purchases with home ownership, type of CRS-2 3 John Makulowich, “ Government Data Mining...cleaning, data integration, data selection, data transformation , (data mining), pattern evaluation, and knowledge presentation.4 A number of advances in

Experimental generation of complex noisy photonic entanglement

NASA Astrophysics Data System (ADS)

Dobek, K.; Karpiński, M.; Demkowicz-Dobrzański, R.; Banaszek, K.; Horodecki, P.

2013-02-01

We present an experimental scheme based on spontaneous parametric down-conversion to produce multiple-photon pairs in maximally entangled polarization states using an arrangement of two type-I nonlinear crystals. By introducing correlated polarization noise in the paths of the generated photons we prepare mixed-entangled states whose properties illustrate fundamental results obtained recently in quantum information theory, in particular those concerning bound entanglement and privacy.

Perceptions and Use of Social Networking Sites in the United States and Ecuador: A Mixed-Methods Approach

ERIC Educational Resources Information Center

Pumper, Megan A.; Yaeger, Jeffery P.; Moreno, Megan A.

2013-01-01

Social networking sites are globally popular. In the United States, these types of sites are perceived positively by users and used at high rates, which has likely yielded personal health behavior displays such as substance abuse and depression. Due to possible cultural influence present on these sites, it remains unknown if SNS could be utilized…

The Social, Political, Economic, and Legal Aspects of Affirmative Action Admission Litigation from 2002-2007 for Five Universities

ERIC Educational Resources Information Center

De Mars, Douglas V.

2010-01-01

Litigation against colleges and universities has prompted the need to re-examine the legalities of the means by which they strive for a diverse student population. Court decisions have resulted in mixed signals about the use of various types of affirmative action policies. This study' method presented an analysis of archival data to provide a…

Allogeneic substitution for nominal antigen-specific T-cell clone reactivity in schistosomiasis.

PubMed Central

Linette, G P; Lammie, P J; Phillips, S M

1986-01-01

The present studies have established the nature of a T-cell clone which demonstrates dual reactivity directed against Schistosoma mansoni antigen presented by syngeneic antigen presenting cells and against allogeneic cells. Clone G4, when stimulated by either antigen (SEA) or allogeneic cells (PL/J), exhibits similar functional and phenotypic characteristics. A subclone of G4, G4A.1, which has been maintained in continuous mixed lymphocyte culture for 12 months (in the absence of SEA), retains comparable reactivity with respect to proliferation and ability to produce lymphokines, transfer delayed-type hypersensitivity, and produce in vitro granulomas in response to SEA. Normal antigenic stimulation is highly contingent upon I-Ab compatibility while antibody blocking experiments map allo-reactivity to I-Eu. The failure of B10.PL spleen cells to stimulate G4, however, suggests that alloreactivity may be directed against the recently described Mls X locus. Both allogeneic and nominal antigen induced T-cell activation are blocked by antibody directed against L3T4A, confirming Class II MHC restriction for both types of stimulation. These studies suggest that stimulation of T cells by either alloantigen or nominal antigen elicits qualitatively similar functional profiles, and further suggest the feasibility of producing large numbers of nominal antigen reactive cloned T cells in the absence of nominal antigen under mixed lymphocyte culture conditions. PMID:2420707

The Role of Complex Treatment in Mixed Leg Ulcers - A Case Report of Vascular, Surgical and Physical Therapy.

PubMed

Wollina, Uwe; Heinig, Birgit; Stelzner, Christian; Hansel, Gesina; Schönlebe, Jacqueline; Tchernev, Georgi; Lotti, Torello

2018-01-25

Leg ulcers are a burden to patients, their families and society. The second most common cause of chronic leg ulcers is the mixed arterio-venous type. An 80-year-old female patient presented to our department due to painful enlarging chronic leg ulcer of mixed arteriovenous origin on her left lower leg. She suffered from peripheral arterial occlusive disease stage I and chronic venous insufficiency Widmer grade IIIa, and a number of comorbidities. The aim of our ulcer treatment was a complete and stable wound closure that was hampered by arterial occlusion, exposed tendon, and renal insiffuciency. To improve the prognosis for ulcer surgery, we performed percutaneous transluminal angioplasty, transcutaneous CO 2 and deep ulcer shaving. The wound was closed by sandwich transplantation using elastin-collagen dermal template and meshed split skin graft. She had a 100% graft take with rapid reduction of severe wound pain. Complex approaches are necessary, to gain optimum results in leg ulcer therapy in mixed leg ulcers. Therapeutic nihilism should be abandonend.

Quality Assessment of Mixed and Ceramic Recycled Aggregates from Construction and Demolition Wastes in the Concrete Manufacture According to the Spanish Standard.

PubMed

Rodríguez-Robles, Desirée; García-González, Julia; Juan-Valdés, Andrés; Morán-Del Pozo, Julia Mª; Guerra-Romero, Manuel I

2014-08-13

Construction and demolition waste (CDW) constitutes an increasingly significant problem in society due to the volume generated, rendering sustainable management and disposal problematic. The aim of this study is to identify a possible reuse option in the concrete manufacturing for recycled aggregates with a significant ceramic content: mixed recycled aggregates (MixRA) and ceramic recycled aggregates (CerRA). In order to do so, several tests are conducted in accordance with the Spanish Code on Structural Concrete (EHE-08) to determine the composition in weight and physic-mechanical characteristics (particle size distributions, fine content, sand equivalent, density, water absorption, flakiness index, and resistance to fragmentation) of the samples for the partial inclusion of the recycled aggregates in concrete mixes. The results of these tests clearly support the hypothesis that this type of material may be suitable for such partial replacements if simple pretreatment is carried out. Furthermore, this measure of reuse is in line with European, national, and regional policies on sustainable development, and presents a solution to the environmental problem caused by the generation of CDW.

Posterior semicircular canal dehiscence: value of VEMP and multidetector CT.

PubMed

Vanspauwen, R; Salembier, L; Van den Hauwe, L; Parizel, P; Wuyts, F L; Van de Heyning, P H

2006-01-01

To illustrate that posterior semicircular canal dehiscence can present similarly to superior semicircular canal dehiscence. The symptomatology initially presented as probable Menière's disease evolving into a mixed conductive hearing loss with a Carhart notch-type perceptive component suggestive of otosclerosis-type stapes fixation. A small hole stapedotomy resulted in a dead ear and a horizontal semicircular canal hypofunction. Recurrent incapacitating vertigo attacks developed. Vestibular evoked myogenic potential (VEMP) testing demonstrated intact vestibulocollic reflexes. Additional evaluation with high resolution multidetector computed tomography (MDCT) of the temporal bone showed a dehiscence of the left posterior semicircular canal. Besides superior semicircular canal dehiscence, posterior semicircular canal dehiscence has to be included in the differential diagnosis of atypical Menière's disease and/or low tone conductive hearing loss. The value of performing MDCT before otosclerosis-type surgery is stressed. VEMP might contribute to establishing the differential diagnosis.

A Model for Displacements Between Parallel Plates That Shows Change of Type from Hyperbolic to Elliptic

NASA Astrophysics Data System (ADS)

Shariati, Maryam; Yortsos, Yannis; Talon, Laurent; Martin, Jerome; Rakotomalala, Nicole; Salin, Dominique

2003-11-01

We consider miscible displacement between parallel plates, where the viscosity is a function of the concentration. By selecting a piece-wise representation, the problem can be considered as ``three-phase'' flow. Assuming a lubrication-type approximation, the mathematical description is in terms of two quasi-linear hyperbolic equations. When the mobility of the middle phase is smaller than its neighbors, the system is genuinely hyperbolic and can be solved analytically. However, when it is larger, an elliptic region develops. This change-of-type behavior is for the first time proved here based on sound physical principles. Numerical solutions with a small diffusion are presented. Good agreement is obtained outside the elliptic region, but not inside, where the numerical results show unstable behavior. We conjecture that for the solution of the real problem in the mixed-type case, the full higher-dimensionality problem must be considered inside the elliptic region, in which the lubrication (parallel-flow) approximation is no longer appropriate. This is discussed in a companion presentation.

7 CFR 52.1858 - Grades of mixed types or varieties of raisins.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Grades of mixed types or varieties of raisins. 52.1858 Section 52.1858 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE...

7 CFR 52.1858 - Grades of mixed types or varieties of raisins.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Grades of mixed types or varieties of raisins. 52.1858 Section 52.1858 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE...

Forest type influences transmission of Phytophthora ramorum in California oak woodlands

Treesearch

J. M. Davidson; H. A. Patterson; A. C. Wickland; E. J. Fichtner; D. M. Rizzo

2011-01-01

The transmission ecology of Phytophthora ramorum from bay laurel (Umbellularia californica) leaves was compared between mixed-evergreen and redwood forest types throughout winter and summer disease cycles in central, coastal California. In a preliminary multisite study, we found that abscission rates of infected leaves were higher at mixed...

One-dimensional Turbulence Models of Type I X-ray Bursts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hou, Chen

Type I X-ray bursts are caused by thermonuclear explosions occurring on the surface of an accreting neutron star in a binary star system. Observations and simulations of these phenomena are of great importance for understanding the fundamental properties of neutron stars and dense matter because the equation of state for cold dense matter can be constrained by the mass-radius relationship of neutron stars. During the bursts, turbulence plays a key role in mixing the fuels and driving the unstable nuclear burning process. This dissertation presents one-dimensional models of photospheric radius expansion bursts with a new approach to simulate turbulent advection.more » Compared with the traditional mixing length theory, the one-dimensional turbulence (ODT) model represents turbulent motions by a sequence of maps that are generated according to a stochastic process. The light curves I obtained with the ODT models are in good agreement with those of the KEPLER model in which the mixing length theory and various diffusive processes are applied. The abundance comparison, however, indicates that the differences in turbulent regions and turbulent diffusivities result in more 12C survival during the bursts in the ODT models, which can make a difference in the superbursts phenomena triggered by unstable carbon burning.« less

The effect of particle properties on the depth profile of buoyant plastics in the ocean

NASA Astrophysics Data System (ADS)

Kooi, Merel; Reisser, Julia; Slat, Boyan; Ferrari, Francesco F.; Schmid, Moritz S.; Cunsolo, Serena; Brambini, Roberto; Noble, Kimberly; Sirks, Lys-Anne; Linders, Theo E. W.; Schoeneich-Argent, Rosanna I.; Koelmans, Albert A.

2016-10-01

Most studies on buoyant microplastics in the marine environment rely on sea surface sampling. Consequently, microplastic amounts can be underestimated, as turbulence leads to vertical mixing. Models that correct for vertical mixing are based on limited data. In this study we report measurements of the depth profile of buoyant microplastics in the North Atlantic subtropical gyre, from 0 to 5 m depth. Microplastics were separated into size classes (0.5-1.5 and 1.5-5.0 mm) and types (‘fragments’ and ‘lines’), and associated with a sea state. Microplastic concentrations decreased exponentially with depth, with both sea state and particle properties affecting the steepness of the decrease. Concentrations approached zero within 5 m depth, indicating that most buoyant microplastics are present on or near the surface. Plastic rise velocities were also measured, and were found to differ significantly for different sizes and shapes. Our results suggest that (1) surface samplers such as manta trawls underestimate total buoyant microplastic amounts by a factor of 1.04-30.0 and (2) estimations of depth-integrated buoyant plastic concentrations should be done across different particle sizes and types. Our findings can assist with improving buoyant ocean plastic vertical mixing models, mass balance exercises, impact assessments and mitigation strategies.

The effect of particle properties on the depth profile of buoyant plastics in the ocean

PubMed Central

Kooi, Merel; Reisser, Julia; Slat, Boyan; Ferrari, Francesco F.; Schmid, Moritz S.; Cunsolo, Serena; Brambini, Roberto; Noble, Kimberly; Sirks, Lys-Anne; Linders, Theo E. W.; Schoeneich-Argent, Rosanna I.; Koelmans, Albert A.

2016-01-01

Most studies on buoyant microplastics in the marine environment rely on sea surface sampling. Consequently, microplastic amounts can be underestimated, as turbulence leads to vertical mixing. Models that correct for vertical mixing are based on limited data. In this study we report measurements of the depth profile of buoyant microplastics in the North Atlantic subtropical gyre, from 0 to 5 m depth. Microplastics were separated into size classes (0.5–1.5 and 1.5–5.0 mm) and types (‘fragments’ and ‘lines’), and associated with a sea state. Microplastic concentrations decreased exponentially with depth, with both sea state and particle properties affecting the steepness of the decrease. Concentrations approached zero within 5 m depth, indicating that most buoyant microplastics are present on or near the surface. Plastic rise velocities were also measured, and were found to differ significantly for different sizes and shapes. Our results suggest that (1) surface samplers such as manta trawls underestimate total buoyant microplastic amounts by a factor of 1.04–30.0 and (2) estimations of depth-integrated buoyant plastic concentrations should be done across different particle sizes and types. Our findings can assist with improving buoyant ocean plastic vertical mixing models, mass balance exercises, impact assessments and mitigation strategies. PMID:27721460

The effect of particle properties on the depth profile of buoyant plastics in the ocean.

PubMed

Kooi, Merel; Reisser, Julia; Slat, Boyan; Ferrari, Francesco F; Schmid, Moritz S; Cunsolo, Serena; Brambini, Roberto; Noble, Kimberly; Sirks, Lys-Anne; Linders, Theo E W; Schoeneich-Argent, Rosanna I; Koelmans, Albert A

2016-10-10

Most studies on buoyant microplastics in the marine environment rely on sea surface sampling. Consequently, microplastic amounts can be underestimated, as turbulence leads to vertical mixing. Models that correct for vertical mixing are based on limited data. In this study we report measurements of the depth profile of buoyant microplastics in the North Atlantic subtropical gyre, from 0 to 5 m depth. Microplastics were separated into size classes (0.5-1.5 and 1.5-5.0 mm) and types ('fragments' and 'lines'), and associated with a sea state. Microplastic concentrations decreased exponentially with depth, with both sea state and particle properties affecting the steepness of the decrease. Concentrations approached zero within 5 m depth, indicating that most buoyant microplastics are present on or near the surface. Plastic rise velocities were also measured, and were found to differ significantly for different sizes and shapes. Our results suggest that (1) surface samplers such as manta trawls underestimate total buoyant microplastic amounts by a factor of 1.04-30.0 and (2) estimations of depth-integrated buoyant plastic concentrations should be done across different particle sizes and types. Our findings can assist with improving buoyant ocean plastic vertical mixing models, mass balance exercises, impact assessments and mitigation strategies.

Modifying mixing and instability growth through the adjustment of initial conditions in a high-energy-density counter-propagating shear experiment on OMEGA

DOE PAGES

Merritt, E. C.; Doss, F. W.; Loomis, E. N.; ...

2015-06-24

Counter-propagating shear experiments conducted at the OMEGA Laser Facility have been evaluating the effect of target initial conditions, specifically the characteristics of a tracer foil located at the shear boundary, on Kelvin-Helmholtz instability evolution and experiment transition toward nonlinearity and turbulence in the high-energy-density (HED) regime. Experiments are focused on both identifying and uncoupling the dependence of the model initial turbulent length scale in variable-density turbulence models of k-ϵ type on competing physical instability seed lengths as well as developing a path toward fully developed turbulent HED experiments. We present results from a series of experiments controllably and independently varyingmore » two initial types of scale lengths in the experiment: the thickness and surface roughness (surface perturbation scale spectrum) of a tracer layer at the shear interface. We show that decreasing the layer thickness and increasing the surface roughness both have the ability to increase the relative mixing in the system, and thus theoretically decrease the time required to begin transitioning to turbulence in the system. In addition, we also show that we can connect a change in observed mix width growth due to increased foil surface roughness to an analytically predicted change in model initial turbulent scale lengths.« less

Photoelectron angular distributions for states of any mixed character: An experiment-friendly model for atomic, molecular, and cluster anions

NASA Astrophysics Data System (ADS)

Khuseynov, Dmitry; Blackstone, Christopher C.; Culberson, Lori M.; Sanov, Andrei

2014-09-01

We present a model for laboratory-frame photoelectron angular distributions in direct photodetachment from (in principle) any molecular orbital using linearly polarized light. A transparent mathematical approach is used to generalize the Cooper-Zare central-potential model to anionic states of any mixed character. In the limit of atomic-anion photodetachment, the model reproduces the Cooper-Zare formula. In the case of an initial orbital described as a superposition of s and p-type functions, the model yields the previously obtained s-p mixing formula. The formalism is further advanced using the Hanstorp approximation, whereas the relative scaling of the partial-wave cross-sections is assumed to follow the Wigner threshold law. The resulting model describes the energy dependence of photoelectron anisotropy for any atomic, molecular, or cluster anions, usually without requiring a direct calculation of the transition dipole matrix elements. As a benchmark case, we apply the p-d variant of the model to the experimental results for NO- photodetachment and show that the observed anisotropy trend is described well using physically meaningful values of the model parameters. Overall, the presented formalism delivers insight into the photodetachment process and affords a new quantitative strategy for analyzing the photoelectron angular distributions and characterizing mixed-character molecular orbitals using photoelectron imaging spectroscopy of negative ions.

Photoelectron angular distributions for states of any mixed character: an experiment-friendly model for atomic, molecular, and cluster anions.

PubMed

Khuseynov, Dmitry; Blackstone, Christopher C; Culberson, Lori M; Sanov, Andrei

2014-09-28

We present a model for laboratory-frame photoelectron angular distributions in direct photodetachment from (in principle) any molecular orbital using linearly polarized light. A transparent mathematical approach is used to generalize the Cooper-Zare central-potential model to anionic states of any mixed character. In the limit of atomic-anion photodetachment, the model reproduces the Cooper-Zare formula. In the case of an initial orbital described as a superposition of s and p-type functions, the model yields the previously obtained s-p mixing formula. The formalism is further advanced using the Hanstorp approximation, whereas the relative scaling of the partial-wave cross-sections is assumed to follow the Wigner threshold law. The resulting model describes the energy dependence of photoelectron anisotropy for any atomic, molecular, or cluster anions, usually without requiring a direct calculation of the transition dipole matrix elements. As a benchmark case, we apply the p-d variant of the model to the experimental results for NO(-) photodetachment and show that the observed anisotropy trend is described well using physically meaningful values of the model parameters. Overall, the presented formalism delivers insight into the photodetachment process and affords a new quantitative strategy for analyzing the photoelectron angular distributions and characterizing mixed-character molecular orbitals using photoelectron imaging spectroscopy of negative ions.

CFD Analysis of Mixing Characteristics of Several Fuel Injectors at Hypervelocity Flow Conditions

NASA Technical Reports Server (NTRS)

Drozda, Tomasz G.; Drummond, J. Philip; Baurle, Robert A.

2016-01-01

CFD analysis is presented of the mixing characteristics and performance of three fuel injectors at hypervelocity flow conditions. The calculations were carried out using the VULCAN-CFD solver and Reynolds-Averaged Simulations (RAS). The high Mach number flow conditions match those proposed for the planned experiments conducted as a part of the Enhanced Injection and Mixing Project (EIMP) at the NASA Langley Research Center. The EIMP aims to investigate scramjet fuel injection and mixing physics, improve the understanding of underlying physical processes, and develop enhancement strategies and functional relationships relevant to flight Mach numbers greater than eight. Because of the high Mach number flow considered, the injectors consist of a fuel placement device, a strut; and a fluidic vortical mixer, a ramp. These devices accomplish the necessary task of distributing and mixing fuel into the supersonic cross-flow albeit via different strategies. Both of these devices were previously studied at lower flight Mach numbers where they exhibited promising performance in terms of mixing efficiency and total pressure recovery. For comparison, a flush-wall injector is also included. This type of injector generally represents the simplest method of introducing fuel into a scramjet combustor, however, at high flight Mach number conditions, the dynamic pressure needed to induce sufficient fuel penetration may be difficult to achieve along with other requirements such as achieving desired levels of fuel-to-air mixing at the required equivalence ratio. The three injectors represent the baseline configurations planned for the experiments. The current work discusses the mixing flow field behavior and differences among the three fuel injectors, mixing performance as described by the mixing efficiency and the total pressure recovery, and performance considerations based on the thrust potential.

Hepatic steatosis background in chronic hepatitis B and C - significance of similarities and differences.

PubMed

Moroşan, Eugenia; Mihailovici, Maria Sultana; Giuşcă, Simona Eliza; Cojocaru, Elena; Avădănei, Elena Roxana; Căruntu, Irina Draga; Teleman, Sergiu

2014-01-01

The aim of our study was to investigate comparatively the steatotic background in viral chronic hepatitis B, C and mixed types, in correlation with the severity degree of specific liver lesions. The study group consisted of 1206 liver biopsy specimens, etiologically diagnosed as hepatitis C - 1021 (84.66%) cases, hepatitis B - 100 (8.29%) cases, hepatitis B and C - 39 (3.23%) cases, hepatitis B and D - 39 (3.23%) cases, hepatitis C and toxicity - six (0.49%) cases, hepatitis B, C and D - one case (0.08%). The histopathological assessment focused on the steatotic lesions associated with inflammation and fibrosis. The cases were classified according to necrosis and inflammatory activity (score between 0-12) and fibrosis (score between 0-4). Our data indicates significant association of steatotic lesions in hepatitis C (76.59%) as opposed to other types of viral hepatitis. In mixed hepatitis B and C, steatotic lesions are more frequent (66.66%) than in chronic hepatitis B (47%) and in mixed chronic B and D hepatitis (48.72%). Steatosis was present in all cases with chronic hepatitis C and associated toxicity. These observations confirm the important aggressiveness of hepatitis C virus as opposed to hepatitis B and D virus. The analysis of the pattern of steatosis in correlation with necrosis and inflammatory activity and fibrosis, respectively, lead to the identification of certain specific elements. Thus, for all types of hepatitis, steatosis is associated predominantly with moderate severity (score 6-8) and progressive expansion of fibrosis (score 2-3). The presence of steatosis does not define hepatic lesions with severe inflammation (score 9-12) nor those with extended fibrosis (score 4). The type of steatosis present is mostly macrovesicular, the transformation into lipid cysts being uncommon. Based on the scoring systems applied in the evaluation of the entire investigated study group, we believe that a possible inclusion of a quantifiable criterion for steatosis could be beneficial in order to complete the characterization of the severity of the lesions, from the point of view of the potential for future evolution, reversible or irreversible.

7 CFR 29.1036 - Mixed Group (M).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed Group (M). 29.1036 Section 29.1036 Agriculture... Type 92) § 29.1036 Mixed Group (M). This group consists of tobacco from three or more groups or two distinctly different groups which are mixed together in various combinations. [49 FR 16755, Apr. 20, 1984...

7 CFR 29.1036 - Mixed Group (M).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed Group (M). 29.1036 Section 29.1036 Agriculture... Type 92) § 29.1036 Mixed Group (M). This group consists of tobacco from three or more groups or two distinctly different groups which are mixed together in various combinations. [49 FR 16755, Apr. 20, 1984...

7 CFR 29.1036 - Mixed Group (M).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed Group (M). 29.1036 Section 29.1036 Agriculture... Type 92) § 29.1036 Mixed Group (M). This group consists of tobacco from three or more groups or two distinctly different groups which are mixed together in various combinations. [49 FR 16755, Apr. 20, 1984...

Demonstration of ATG Process for Stabilizing Mercury (<260 ppm) Contaminated Mixed Waste. Mixed Waste Focus Area. OST Reference # 2407

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

1999-09-01

Mercury contaminated wastes in many forms are present at various U. S. Department of Energy (DOE) sites. Based on efforts led by the Mixed Waste Focus Area (MWFA) and its Mercury Working Group (HgWG), the inventory of wastes contaminated with <260 ppm mercury and with radionuclides stored at various DOE sites is estimated to be approximately 6,000 m 3). At least 26 different DOE sites have this type of mixed low-level waste in their storage facilities. Extraction methods are required to remove mercury from waste containing >260 ppm levels, but below 260 ppm Hg contamination levels the U. S. Environmentalmore » Protection Agency (EPA) does not require removal of mercury from the waste. Steps must still be taken, however, to ensure that the final waste form does not leach mercury in excess of the limit for mercury prescribed in the Resource Conservation and Recovery Act (RCRA) when subjected to the Toxicity Characteristic Leaching Procedure (TCLP). At this time, the limit is 0.20 mg/L. However, in the year 2000, the more stringent Universal Treatment Standard (UTS) of 0.025 mg/L will be used as the target endpoint. Mercury contamination in the wastes at DOE sites presents a challenge because it exists in various forms, such as soil, sludges, and debris, as well as in different chemical species of mercury. Stabilization is of interest for radioactively contaminated mercury waste (<260 ppm Hg) because of its success with particular wastes, such as soils, and its promise of applicability to a broad range of wastes. However, stabilization methods must be proven to be adequate to meet treatment standards. It must also be proven feasible in terms of economics, operability, and safety. To date, no standard method of stabilization has been developed and proven for such varying waste types as those within the DOE complex.« less

Mixed-methods research in nursing - a critical review.

PubMed

Bressan, Valentina; Bagnasco, Annamaria; Aleo, Giuseppe; Timmins, Fiona; Barisone, Michela; Bianchi, Monica; Pellegrini, Ramona; Sasso, Loredana

2017-10-01

To review the use of mixed-methods research in nursing with a particular focus on the extent to which current practice informs nurse researchers. It also aimed to highlight gaps in current knowledge, understanding and reporting of this type of research. Mixed-methods research is becoming increasingly popular among nurses and healthcare professionals. Emergent findings from this type of research are very useful for nurses in practice. The combination of both quantitative and qualitative methods provides a scientific base for practice but also richness from the qualitative enquiry. However, at the same time mixed-methods research is underdeveloped. This study identified mixed-methods research papers and critically evaluated their usefulness for research practice. To support the analysis, we performed a two-stage search using CINAHL to find papers with titles that included the key term 'mixed method'. An analysis of studies that used mixed-methods research revealed some inconsistencies in application and reporting. Attempts to use two distinct research methods in these studies often meant that one or both aspects had limitations. Overall methods were applied in a less rigorous way. This has implications for providing somewhat limited direction for novice researchers. There is also potential for application of evidence in healthcare practice that limited validity. This study highlights current gaps in knowledge, understanding and reporting of mixed-methods research. While these methods are useful to gain insight into clinical problems nurses lack guidance with this type of research. This study revealed that the guidance provided by current mixed-methods research is inconsistent and incomplete and this compounds the lack of available direction. There is an urgent need to develop robust guidelines for using mixed-methods research so that findings may be critically implemented in practice. © 2016 John Wiley & Sons Ltd.

Further Improvements to Linear Mixed Models for Genome-Wide Association Studies

PubMed Central

Widmer, Christian; Lippert, Christoph; Weissbrod, Omer; Fusi, Nicolo; Kadie, Carl; Davidson, Robert; Listgarten, Jennifer; Heckerman, David

2014-01-01

We examine improvements to the linear mixed model (LMM) that better correct for population structure and family relatedness in genome-wide association studies (GWAS). LMMs rely on the estimation of a genetic similarity matrix (GSM), which encodes the pairwise similarity between every two individuals in a cohort. These similarities are estimated from single nucleotide polymorphisms (SNPs) or other genetic variants. Traditionally, all available SNPs are used to estimate the GSM. In empirical studies across a wide range of synthetic and real data, we find that modifications to this approach improve GWAS performance as measured by type I error control and power. Specifically, when only population structure is present, a GSM constructed from SNPs that well predict the phenotype in combination with principal components as covariates controls type I error and yields more power than the traditional LMM. In any setting, with or without population structure or family relatedness, a GSM consisting of a mixture of two component GSMs, one constructed from all SNPs and another constructed from SNPs that well predict the phenotype again controls type I error and yields more power than the traditional LMM. Software implementing these improvements and the experimental comparisons are available at http://microsoft.com/science. PMID:25387525

Further Improvements to Linear Mixed Models for Genome-Wide Association Studies

NASA Astrophysics Data System (ADS)

Widmer, Christian; Lippert, Christoph; Weissbrod, Omer; Fusi, Nicolo; Kadie, Carl; Davidson, Robert; Listgarten, Jennifer; Heckerman, David

2014-11-01

We examine improvements to the linear mixed model (LMM) that better correct for population structure and family relatedness in genome-wide association studies (GWAS). LMMs rely on the estimation of a genetic similarity matrix (GSM), which encodes the pairwise similarity between every two individuals in a cohort. These similarities are estimated from single nucleotide polymorphisms (SNPs) or other genetic variants. Traditionally, all available SNPs are used to estimate the GSM. In empirical studies across a wide range of synthetic and real data, we find that modifications to this approach improve GWAS performance as measured by type I error control and power. Specifically, when only population structure is present, a GSM constructed from SNPs that well predict the phenotype in combination with principal components as covariates controls type I error and yields more power than the traditional LMM. In any setting, with or without population structure or family relatedness, a GSM consisting of a mixture of two component GSMs, one constructed from all SNPs and another constructed from SNPs that well predict the phenotype again controls type I error and yields more power than the traditional LMM. Software implementing these improvements and the experimental comparisons are available at http://microsoft.com/science.

Further improvements to linear mixed models for genome-wide association studies.

PubMed

Widmer, Christian; Lippert, Christoph; Weissbrod, Omer; Fusi, Nicolo; Kadie, Carl; Davidson, Robert; Listgarten, Jennifer; Heckerman, David

2014-11-12

We examine improvements to the linear mixed model (LMM) that better correct for population structure and family relatedness in genome-wide association studies (GWAS). LMMs rely on the estimation of a genetic similarity matrix (GSM), which encodes the pairwise similarity between every two individuals in a cohort. These similarities are estimated from single nucleotide polymorphisms (SNPs) or other genetic variants. Traditionally, all available SNPs are used to estimate the GSM. In empirical studies across a wide range of synthetic and real data, we find that modifications to this approach improve GWAS performance as measured by type I error control and power. Specifically, when only population structure is present, a GSM constructed from SNPs that well predict the phenotype in combination with principal components as covariates controls type I error and yields more power than the traditional LMM. In any setting, with or without population structure or family relatedness, a GSM consisting of a mixture of two component GSMs, one constructed from all SNPs and another constructed from SNPs that well predict the phenotype again controls type I error and yields more power than the traditional LMM. Software implementing these improvements and the experimental comparisons are available at http://microsoft.com/science.

[Discrimination of types of polyacrylamide based on near infrared spectroscopy coupled with least square support vector machine].

PubMed

Zhang, Hong-Guang; Yang, Qin-Min; Lu, Jian-Gang

2014-04-01

In this paper, a novel discriminant methodology based on near infrared spectroscopic analysis technique and least square support vector machine was proposed for rapid and nondestructive discrimination of different types of Polyacrylamide. The diffuse reflectance spectra of samples of Non-ionic Polyacrylamide, Anionic Polyacrylamide and Cationic Polyacrylamide were measured. Then principal component analysis method was applied to reduce the dimension of the spectral data and extract of the principal compnents. The first three principal components were used for cluster analysis of the three different types of Polyacrylamide. Then those principal components were also used as inputs of least square support vector machine model. The optimization of the parameters and the number of principal components used as inputs of least square support vector machine model was performed through cross validation based on grid search. 60 samples of each type of Polyacrylamide were collected. Thus a total of 180 samples were obtained. 135 samples, 45 samples for each type of Polyacrylamide, were randomly split into a training set to build calibration model and the rest 45 samples were used as test set to evaluate the performance of the developed model. In addition, 5 Cationic Polyacrylamide samples and 5 Anionic Polyacrylamide samples adulterated with different proportion of Non-ionic Polyacrylamide were also prepared to show the feasibilty of the proposed method to discriminate the adulterated Polyacrylamide samples. The prediction error threshold for each type of Polyacrylamide was determined by F statistical significance test method based on the prediction error of the training set of corresponding type of Polyacrylamide in cross validation. The discrimination accuracy of the built model was 100% for prediction of the test set. The prediction of the model for the 10 mixing samples was also presented, and all mixing samples were accurately discriminated as adulterated samples. The overall results demonstrate that the discrimination method proposed in the present paper can rapidly and nondestructively discriminate the different types of Polyacrylamide and the adulterated Polyacrylamide samples, and offered a new approach to discriminate the types of Polyacrylamide.

How Do Le Fort-Type Fractures Present in a Pediatric Cohort?

PubMed

Macmillan, Alexandra; Lopez, Joseph; Luck, J D; Faateh, Muhammad; Manson, Paul; Dorafshar, Amir H

2018-05-01

Le Fort-type fractures are very rare in children, and there is a paucity of literature presenting their frequency and characteristics. The purpose of this study was to determine the etiology, frequency, and fracture patterns of children with severe facial trauma associated with pterygoid plate fractures in a pediatric cohort. We performed a retrospective cohort study of all children aged younger than 16 years with pterygoid plate and facial fractures who presented to our institute between 1990 and 2010. Patient charts and radiologic records were reviewed for demographic and fracture characteristics. Patients were categorized into 2 groups as per facial fracture pattern: non-Le Fort-type fractures (group A) and Le Fort-type fractures (group B). Other variables including dentition age, frontal sinus development, mechanism of injury, injury severity, and concomitant injuries were recorded. Univariate methods were used to compare groups. We identified 24 children; 25% were girls, and 20.8% were of nonwhite race. Most presented with Le Fort-type fracture patterns (group B, 66.7%). Age was significantly different between group A and group B (mean, 5.9 years and 9.9 years, respectively; P = .009). No significant differences in Injury Severity Score, rate of operative repair, and length of stay were found between groups. Most children with severe facial fractures and pterygoid plate fractures presented with Le Fort-type fracture patterns in our cohort. The mean age of children with Le Fort-type fractures was greater than in those with non-Le Fort-type patterns. However, Le Fort-type fractures did occur in younger children with deciduous and mixed dentition. Copyright © 2017 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Randomized clinical trial of encapsulated and hand-mixed glass-ionomer ART restorations: one-year follow-up

PubMed Central

Freitas, Maria Cristina Carvalho de Almendra; Fagundes, Ticiane Cestari; Modena, Karin Cristina da Silva; Cardia, Guilherme Saintive; Navarro, Maria Fidela de Lima

2018-01-01

Abstract Objective This prospective, randomized, split-mouth clinical trial evaluated the clinical performance of conventional glass ionomer cement (GIC; Riva Self-Cure, SDI), supplied in capsules or in powder/liquid kits and placed in Class I cavities in permanent molars by the Atraumatic Restorative Treatment (ART) approach. Material and Methods A total of 80 restorations were randomly placed in 40 patients aged 11-15 years. Each patient received one restoration with each type of GIC. The restorations were evaluated after periods of 15 days (baseline), 6 months, and 1 year, according to ART criteria. Wilcoxon matched pairs, multivariate logistic regression, and Gehan-Wilcoxon tests were used for statistical analysis. Results Patients were evaluated after 15 days (n=40), 6 months (n=34), and 1 year (n=29). Encapsulated GICs showed significantly superior clinical performance compared with hand-mixed GICs at baseline (p=0.017), 6 months (p=0.001), and 1 year (p=0.026). For hand-mixed GIC, a statistically significant difference was only observed over the period of baseline to 1 year (p=0.001). Encapsulated GIC presented statistically significant differences for the following periods: 6 months to 1 year (p=0.028) and baseline to 1 year (p=0.002). Encapsulated GIC presented superior cumulative survival rate than hand-mixed GIC over one year. Importantly, both GICs exhibited decreased survival over time. Conclusions Encapsulated GIC promoted better ART performance, with an annual failure rate of 24%; in contrast, hand-mixed GIC demonstrated a failure rate of 42%. PMID:29364343

Looking at flood trends with different eyes: the value of a fuzzy flood classification scheme

NASA Astrophysics Data System (ADS)

Sikorska, A. E.; Viviroli, D.; Brunner, M. I.; Seibert, J.

2016-12-01

Natural floods can be governed by several processes such as heavy rainfall or intense snow- or glacier-melt. These processes result in different flood characteristics in terms of flood shape and magnitude. Pooling floods of different types might therefore impair the analyses of flood frequencies and trends. Thus, the categorization of flood events into different flood type classes and the determination of their respective frequencies is essential for a better understanding and for the prediction of floods. In reality however most flood events are caused by a mix of processes and a unique determination of a flood type per event often becomes difficult. This study proposes an innovative method for a more reliable categorization of floods according to similarities in flood drivers. The categorization of floods into subgroups relies on a fuzzy decision tree. While the classical (crisp) decision tree allows for the identification of only one flood type per event, the fuzzy approach enables the detection of mixed types. Hence, events are represented as a spectrum of six possible flood types, while a degree of acceptance attributed to each of them specifies the importance of each type during the event formation. Considered types are flash, short rainfall, long rainfall, snow-melt, rainfall-on-snow, and, in high altitude watersheds, also glacier-melt floods. The fuzzy concept also enables uncertainty present in the identification of flood processes and in the method to be incorporated into the flood categorization process. We demonstrate, for a set of nine Swiss watersheds and 30 years of observations, that this new concept provides more reliable flood estimates than the classical approach as it allows for a more dedicated flood prevention technique adapted to a specific flood type.

Evaluation of Parotid Salivary Glucose Level for Clinical Diagnosis and Monitoring Type 2 Diabetes Mellitus Patients.

PubMed

Wang, Beibei; Du, Juan; Zhu, Zhao; Ma, Zhihong; Wang, Songlin; Shan, Zhaochen

2017-01-01

Background . To investigate the relationships among blood glucose, mixed saliva glucose, and parotid glucose in type 2 diabetes patients and to evaluate the diagnostic and monitoring value of salivary gland glucose in patients with type 2 diabetes (type 2DM). Material and Methods . Thirty patients with type 2DM and 30 healthy age- and sex-matched individuals were included in this study. Glucose levels in unstimulated mixed saliva and in unstimulated parotid saliva were measured by the glucose oxidase peroxidase method. Results . The blood glucose and parotid salivary glucose levels in type 2DM patients were significantly higher than those in the controls ( P < 0.05). The blood glucose, parotid salivary glucose, and mixed salivary glucose were 7.46 ± 1.44 mmol/L, 0.18 ± 0.19 mmol/L, and 3.17 × 10 -2 ± 2.84 × 10 -2  mmol/L, respectively, in the type 2DM group; the corresponding glucose levels in the control group were 5.56 ± 0.71 mmol/L, 7.70 × 10 -2 ± 6.02 × 10 -2  mmol/L, and 3.47 × 10 -2 ± 2.79 × 10 -2  mmol/L. The parotid salivary and blood glucose levels in type 2DM patients were strongly correlated; the linear regression equation for blood glucose and parotid salivary glucose was Y = 6.267 X + 6.360, with r = 0.810. However, mixed salivary glucose levels were not significantly different in the type 2 diabetes group compared with the control group. Conclusion . Our results suggest that parotid salivary glucose has potential as a biomarker to monitor type 2DM and as a painless, noninvasive method for the management of type 2DM.

WT1 immunoreactivity in breast carcinoma: selective expression in pure and mixed mucinous subtypes.

PubMed

Domfeh, Akosua B; Carley, AnnaMarie L; Striebel, Joan M; Karabakhtsian, Rouzan G; Florea, Anca V; McManus, Kim; Beriwal, Sushil; Bhargava, Rohit

2008-10-01

Current literature suggests that strong WT1 expression in a carcinoma of unknown origin virtually excludes a breast primary. Our previous pilot study on WT1 expression in breast carcinomas has shown WT1 expression in approximately 10% of carcinomas that show mixed micropapillary and mucinous morphology (Mod Pathol 2007;20(Suppl 2):38A). To definitively assess as to what subtype of breast carcinoma might express WT1 protein, we examined 153 cases of invasive breast carcinomas. These consisted of 63 consecutive carcinomas (contained 1 mucinous tumor), 20 cases with micropapillary morphology (12 pure and 8 mixed), 6 micropapillary 'mimics' (ductal no special type carcinomas with retraction artifacts), 33 pure mucinous carcinomas and 31 mixed mucinous carcinomas (mucinous mixed with other morphologic types). Overall, WT1 expression was identified in 33 carcinomas, that is, 22 of 34 (65%) pure mucinous carcinomas and in 11 of 33 (33%) mixed mucinous carcinomas. The non-mucinous component in these 11 mixed mucinous carcinomas was either a ductal no special type carcinoma (8 cases) or a micropapillary component (3 cases). WT1 expression level was similar in both the mucinous and the non-mucinous components. The degree of WT1 expression was generally weak to moderate (>90% cases) and rarely strong (<10% cases). None of the breast carcinoma subtype unassociated with mucinous component showed WT1 expression.

[Characteristics of the aggregative state of the substrate in the reaction of 5-lipoxygenase oxidation of linoleic acid].

PubMed

Butovich, I A; Kharchenko, O V; Paboka, Iu N; Kazachkov, M G

2001-01-01

5-lipoxygenase (EC 1.13.11.12) oxidizes polyunsaturated fatty acids by molecular oxygen. The enzyme acts in close contact with the cell membranes, which main components are ionic and non-ionic lipids. In order to investigate the kinetic parameters of 5-lipoxygenase reaction in vitro, extremely hydrophobic fatty acid substrate (linoleic acid) should be solubilized in the reaction mixture. We used Lubrol PX ("Sigma" Chem. Co), as a non-ionic detergent consisted of oligoethylene glycol and fatty alcohol. Linoleic acid and Lubrol PX formed mixed micelles thus solubilizing the fatty acid substrate in a buffer with appropriate pH. We have studied the sizes and shapes of mixed micelles Lubrol PX/linoleic acid (aggregates type 1) and Lubrol PX/linoleic acid/SDS (aggregates type 2; SDS was an effective activator of potato tuber 5-lipoxygenase) by means of gel-filtration and laser light scattering techniques. The parameters under investigation were molecular weights, Stocks radii and shapes of the mixed micelles. The average molecular weights and Stocks radii of the mixed micelles type 1 determined by mean of gel-filtration on Sephadex G-200 were 95,142 +/- 5184 Da and 3.45 +/- 0.11 nm, respectively. The same parameters for the mixed micelles type 2 were 73,694 +/- 893 Da and 3.02 +/- 0.02 nm, respectively. The strong similarity in physicochemical parameters for both types of mixed micelles indicated that SDS did not influence the size and shape of mixed micelles of Lubrol PX and linoleic acid. The activatory action of SDS on potato tuber lipoxygenase may be a result of electrostatic effect or direct participation of SDS in enzymatic catalysis. The laser light scattering technique allowed to determine two main fraction of particles in type 1 system with hydrodynamic diameters 2.6 and 5.7 nm and relative contribution to light scattering 13 and 87%, respectively. The particles with d = 5.7 nm were interpreted as the mixed micelles. The particles with d = 2.6 nm were interpreted as isolated molecules of Lubrol PX, linoleic acid and (or) their premicellar aggregates. The data obtained are to be used in creation of reliable physical and mathematical models of 5-lipoxygenase.

Pulse Jet Mixing Tests With Noncohesive Solids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyer, Perry A.; Bamberger, Judith A.; Enderlin, Carl W.

2009-05-11

This report summarizes results from pulse jet mixing (PJM) tests with noncohesive solids in Newtonian liquid conducted during FY 2007 and 2008 to support the design of mixing systems for the Hanford Waste Treatment and Immobilization Plant (WTP). Tests were conducted at three geometric scales using noncohesive simulants. The test data were used to independently develop mixing models that can be used to predict full-scale WTP vessel performance and to rate current WTP mixing system designs against two specific performance requirements. One requirement is to ensure that all solids have been disturbed during the mixing action, which is important tomore » release gas from the solids. The second requirement is to maintain a suspended solids concentration below 20 weight percent at the pump inlet. The models predict the height to which solids will be lifted by the PJM action, and the minimum velocity needed to ensure all solids have been lifted from the floor. From the cloud height estimate we can calculate the concentration of solids at the pump inlet. The velocity needed to lift the solids is slightly more demanding than "disturbing" the solids, and is used as a surrogate for this metric. We applied the models to assess WTP mixing vessel performance with respect to the two perform¬ance requirements. Each mixing vessel was evaluated against these two criteria for two defined waste conditions. One of the wastes was defined by design limits and one was derived from Hanford waste characterization reports. The assessment predicts that three vessel types will satisfy the design criteria for all conditions evaluated. Seven vessel types will not satisfy the performance criteria used for any of the conditions evaluated. The remaining three vessel types provide varying assessments when the different particle characteristics are evaluated. The assessment predicts that three vessel types will satisfy the design criteria for all conditions evaluated. Seven vessel types will not satisfy the performance criteria used for any of the conditions evaluated. The remaining three vessel types provide varying assessments when the different particle characteristics are evaluated. The HLP-022 vessel was also evaluated using 12 m/s pulse jet velocity with 6-in. nozzles, and this design also did not satisfy the criteria for all of the conditions evaluated.« less

Damage and mortality assessment of redwood and mixed conifer forest types in Santa Cruz County following wildfire

Treesearch

Steve R. Auten; Nadia Hamey

2012-01-01

On August 12, 2009, the Lockheed Fire ignited the west slope of the Santa Cruz Mountains burning approximately 7,819 acres. A mixture of vegetation types were in the path of the fire, including approximately 2,420 acres of redwood forest and 1,951 acres of mixed conifer forest types representative of the Santa Cruz Mountains. Foresters and land managers were left with...

A cost-comparison methodology for selecting appropriate hot-mix asphalt materials.

DOT National Transportation Integrated Search

2007-01-01

The Virginia Department of Transportation's (VDOT) Road and Bridge Specifications lists 9 dense-graded hot-mix asphalt (HMA) surface mixes (three aggregate gradations x three binder types) that could be used on Virginia's highways. VDOT's Special Pro...

The marketing mix and development of medical tourism in shiraz.

PubMed

Jabbari, Alireza; Rahimi Zarchi, Mohammad Kazem; Kavosi, Zahra; Shafaghat, Tahere; Keshtkaran, Ali

2013-01-01

In recent years, medical tourism market has been raised as one of the income-earning and competitive industries in the world and is considered as a modern field of advanced tourism. Therefore, a great number of countries are seeking to develop this type of tourism and one of the strategies for developing this industry is using the marketing mix elements. This study was a descriptive-analytic and cross sectional one. The research community included all the public and private hospitals of Shiraz among which, 7 public and 9 private hospitals were studied. The study data were collected through a researcher-made check list whose face and content validity was confirmed by the experts. Then, the data were entered into the SPSS statistical software. According to the objectives of the study, the descriptive results were presented in frequency tables and Chi-square test was used for data analysis. In addition, P<0.05 was considered as statistically significant. According to the results, both public and private hospitals of Shiraz were in the best condition regarding staff and physician mix and in the worst condition concerning promoting and facilities mixes. No significant difference was found between public and private hospitals regarding the mixes. From marketing mix elements view, paying more attention to media advertisements and providing more facilities can improve the status of the hospitals which, consequently, results in attracting more medical tourists and developing this industry in Shiraz.

Measurement of inflammatory cytokines and thrombomodulin in chronic subdural hematoma.

PubMed

Kitazono, Masatoshi; Yokota, Hiroyuki; Satoh, Hidetaka; Onda, Hidetaka; Matsumoto, Gaku; Fuse, Akira; Teramoto, Akira

2012-01-01

Inflammation and the coagulation system may influence the genesis of chronic subdural hematoma (CSDH). The appearance of CSDH on computed tomography (CT) varies with the stage of the hematoma. This study investigated the pathogenesis and the recurrence of CSDH by comparing cytokine levels with the CT features of CSDH in 26 patients with 34 CSDHs who underwent single burr-hole surgery at our hospital between October 2004 and November 2006. The hematoma components removed during the procedure were examined, and the hematoma serum levels of cytokines measured such as thrombomodulin (TM), interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), and interleukin-10 (IL-10). Using CT, mixed density hematomas were distinguished from other homogeneous hematomas, and found that the TM level was significantly higher in mixed density hematomas than in homogeneous hematomas (p = 0.043). Mixed density hematomas were classified into three subtypes (laminar, separated, and trabecular hematomas). The TM level was significantly higher in laminar and separated hematomas than in other hematomas (p = 0.01). The levels of IL-6, TNFα, and IL-10 were extremely high, but showed no significant differences in relation to the CT features. Mixed density hematomas had high recurrence rate, as reported previously, and TM level was high in mixed density hematomas such as laminar and separated mixed density hematomas. The present findings suggest that the types of CSDH associated with high TM levels tend to have higher recurrence rate.

Estimating the Numerical Diapycnal Mixing in the GO5.0 Ocean Model

NASA Astrophysics Data System (ADS)

Megann, A.; Nurser, G.

2014-12-01

Constant-depth (or "z-coordinate") ocean models such as MOM4 and NEMO have become the de facto workhorse in climate applications, and have attained a mature stage in their development and are well understood. A generic shortcoming of this model type, however, is a tendency for the advection scheme to produce unphysical numerical diapycnal mixing, which in some cases may exceed the explicitly parameterised mixing based on observed physical processes, and this is likely to have effects on the long-timescale evolution of the simulated climate system. Despite this, few quantitative estimations have been made of the magnitude of the effective diapycnal diffusivity due to numerical mixing in these models. GO5.0 is the latest ocean model configuration developed jointly by the UK Met Office and the National Oceanography Centre (Megann et al, 2014), and forms part of the GC1 and GC2 climate models. It uses version 3.4 of the NEMO model, on the ORCA025 ¼° global tripolar grid. We describe various approaches to quantifying the numerical diapycnal mixing in this model, and present results from analysis of the GO5.0 model based on the isopycnal watermass analysis of Lee et al (2002) that indicate that numerical mixing does indeed form a significant component of the watermass transformation in the ocean interior.

Receptivity of the compressible mixing layer

NASA Astrophysics Data System (ADS)

Barone, Matthew F.; Lele, Sanjiva K.

2005-09-01

Receptivity of compressible mixing layers to general source distributions is examined by a combined theoretical/computational approach. The properties of solutions to the adjoint Navier Stokes equations are exploited to derive expressions for receptivity in terms of the local value of the adjoint solution. The result is a description of receptivity for arbitrary small-amplitude mass, momentum, and heat sources in the vicinity of a mixing-layer flow, including the edge-scattering effects due to the presence of a splitter plate of finite width. The adjoint solutions are examined in detail for a Mach 1.2 mixing-layer flow. The near field of the adjoint solution reveals regions of relatively high receptivity to direct forcing within the mixing layer, with receptivity to nearby acoustic sources depending on the source type and position. Receptivity ‘nodes’ are present at certain locations near the splitter plate edge where the flow is not sensitive to forcing. The presence of the nodes is explained by interpretation of the adjoint solution as the superposition of incident and scattered fields. The adjoint solution within the boundary layer upstream of the splitter-plate trailing edge reveals a mechanism for transfer of energy from boundary-layer stability modes to Kelvin Helmholtz modes. Extension of the adjoint solution to the far field using a Kirchhoff surface gives the receptivity of the mixing layer to incident sound from distant sources.

Study of the peculiarities of multiparticle production via event-by-event analysis in asymmetric nucleus-nucleus interactions

NASA Astrophysics Data System (ADS)

Fedosimova, Anastasiya; Gaitinov, Adigam; Grushevskaya, Ekaterina; Lebedev, Igor

2017-06-01

In this work the study on the peculiarities of multiparticle production in interactions of asymmetric nuclei to search for unusual features of such interactions, is performed. A research of long-range and short-range multiparticle correlations in the pseudorapidity distribution of secondary particles on the basis of analysis of individual interactions of nuclei of 197 Au at energy 10.7 AGeV with photoemulsion nuclei, is carried out. Events with long-range multiparticle correlations (LC), short-range multiparticle correlations (SC) and mixed type (MT) in pseudorapidity distribution of secondary particles, are selected by the Hurst method in accordance with Hurst curve behavior. These types have significantly different characteristics. At first, they have different fragmentation parameters. Events of LC type are processes of full destruction of the projectile nucleus, in which multicharge fragments are absent. In events of mixed type several multicharge fragments of projectile nucleus are discovered. Secondly, these two types have significantly different multiplicity distribution. The mean multiplicity of LC type events is significantly more than in mixed type events. On the basis of research of the dependence of multiplicity versus target-nuclei fragments number for events of various types it is revealed, that the most considerable multiparticle correlations are observed in interactions of the mixed type, which correspond to the central collisions of gold nuclei and nuclei of CNO-group, i.e. nuclei with strongly asymmetric volume, nuclear mass, charge, etc. Such events are characterised by full destruction of the target-nucleus and the disintegration of the projectile-nucleus on several multi-charged fragments.

Analysis of earthquake clustering and source spectra in the Salton Sea Geothermal Field

NASA Astrophysics Data System (ADS)

Cheng, Y.; Chen, X.

2015-12-01

The Salton Sea Geothermal field is located within the tectonic step-over between San Andreas Fault and Imperial Fault. Since the 1980s, geothermal energy exploration has resulted with step-like increase of microearthquake activities, which mirror the expansion of geothermal field. Distinguishing naturally occurred and induced seismicity, and their corresponding characteristics (e.g., energy release) is important for hazard assessment. Between 2008 and 2014, seismic data recorded by a local borehole array were provided public access from CalEnergy through SCEC data center; and the high quality local recording of over 7000 microearthquakes provides unique opportunity to sort out characteristics of induced versus natural activities. We obtain high-resolution earthquake location using improved S-wave picks, waveform cross-correlation and a new 3D velocity model. We then develop method to identify spatial-temporally isolated earthquake clusters. These clusters are classified into aftershock-type, swarm-type, and mixed-type (aftershock-like, with low skew, low magnitude and shorter duration), based on the relative timing of largest earthquakes and moment-release. The mixed-type clusters are mostly located at 3 - 4 km depth near injection well; while aftershock-type clusters and swarm-type clusters also occur further from injection well. By counting number of aftershocks within 1day following mainshock in each cluster, we find that the mixed-type clusters have much higher aftershock productivity compared with other types and historic M4 earthquakes. We analyze detailed spatial variation of 'b-value'. We find that the mixed-type clusters are mostly located within high b-value patches, while large (M>3) earthquakes and other types of clusters are located within low b-value patches. We are currently processing P and S-wave spectra to analyze the spatial-temporal correlation of earthquake stress parameter and seismicity characteristics. Preliminary results suggest that the mixed-type clusters and high b-value patches are spatially correlated with low stress drop earthquakes, indicating high-productivity microearthquakes within low differential stress region, potentially due to deeper injection activities.

Modern epidemiology of hepatitis A in the north-western region of the Russian Federation.

PubMed

Shliakhtenko, L; Plotnikova, V; Levakova, I; Rubis, L; Solovieva, E; Mukomolov, S

2008-10-01

The epidemiological features of hepatitis A virus (HAV) infection were studied in eleven territories located in the north-western region of the Russian Federation. The dynamics of HAV infection in Russia and in the region were evaluated during a 17-year period. The age-specific incidence was calculated and 229 305 patients with acute HAV were identified. The analysed database included HA mixed with other viral hepatitis infections: it included information about 8 809 HAV patients. Special attention has been paid to the sero-epidemiological studies conducted in St Petersburg city. These studies included analysis of age-specific incidence in persons 20 years of age and older during 6 years and testing of blood sera from 1 892 healthy persons for IgG anti-HAV. In general there is a trend to reduction of HAV incidence in Russia, and in the north-western region, high indices were registered in some provinces in different years. It was established three types of age-specific incidence distribution: predominated incidence in 3-14 years of age (first type), 15-29 years of age (second type) and uniform distribution in different age groups (third type). It was shown that decrease of HAV incidence in children and young adults lead to the reduction of sero-positivity level in the groups 20+ years of age. These characteristics should be taken in account to define indications for HAV vaccine prophylaxis. HAV infection in 10-13% of cases mixed with acute or chronic hepatitis B and C in the last 15 years in St Petersburg. In the middle of 1990s, HAV mostly mixed with acute viral hepatitis of different aetiology, but in the modern time predominated type of mixture was presented by HAV and chronic HBV and HCV infections. The obtained results are useful for viral hepatitis surveillance and control.

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 2 2012-10-01 2012-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 2 2013-10-01 2013-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

49 CFR 173.459 - Mixing of fissile material packages with non-fissile or fissile-excepted material packages.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 2 2014-10-01 2014-10-01 false Mixing of fissile material packages with non... (Radioactive) Materials § 173.459 Mixing of fissile material packages with non-fissile or fissile-excepted material packages. Mixing of fissile material packages with other types of Class 7 (radioactive) materials...

Impact of Blood Mixing and ABO Compatibility on Platelet-Leukocyte Aggregations and Platelet P-Selectin Expression: An in Vitro Study.

PubMed

Huang, Go-Shine; Hu, Mei-Hua; Lin, Tso-Chou; Tsai, Yi-Ting; Lin, Chih-Yuan; Ke, Hung-Yen; Zheng, Xu-Zhi; Lin, Yi-Chang; Tsai, Chien-Sung

2018-05-01

Effects of blood transfusions on platelet- and leukocyte-related inflammation are unclear. We simulated transfusion using in vitro blood mixing to evaluate platelet-leukocyte aggregations (PLA) and platelet P-selectin expression, and the mechanism of PLA. Donor packed red blood cells (pRBCs) were obtained from a blood bank. Recipient whole blood samples were obtained from patients undergoing cardiac surgery. Blood sample mixtures were divided into four groups: group M, cross-matched blood type mixing; group O, donor type O with other blood type mixing (A, B, or AB); group S, ABO type-specific uncross-matched blood mixing; and group I, ABO incompatibility mixing. Donor pRBCs were added to recipient blood to reach 1%, 5%, and 10% (vol/vol) concentrations. Blood sample mixtures were analyzed to determine the PLA; P-selectin expression; and leukocyte CD11a, CD11b, and CD18 subunits of integrin expression. Analysis of variance tests were used to analyze differences. PLA significantly increased only in groups O and I (P = 0.003 and P < 0.001). Subpopulations of leukocytes significantly increased in all groups. There were no significant differences among the four groups (P = 0.578) in PLA increase. Although there was no significant effect on P-selectin expression (P = 1.000) and leukocyte CD11a and CD18 expression (P = 0.999, P = 0.422) within and between the groups, there was an increase in CD11b expression (P = 0.018). Blood mixing can increase PLA, especially in platelet-neutrophil and platelet-monocyte aggregations, possibly through nonhemolytic reactions. The CD11b integrin with CD18 may play a role in the formation of PLA.

Microbial Activity in Peat Soil Treated With Ordinary Portland Cement (OPC) and Coal Ashes

NASA Astrophysics Data System (ADS)

Rahman, J. A.; Mohamed, R. M. S. R.; Al-Gheethi, A. A.

2018-04-01

Peat soil is a cumulative of decayed plant fragment which developed as a result of microbial activity. The microbes degrade the organic matter in the peat soils by the production of hydrolysis enzyme. The least decomposed peat, known as fibric peat has big particles and retain lots of water. This made peat having high moisture content, up to 1500 %. The most decomposed peat known as sapric peat having fines particles and less void ratio. The present study aimed to understand the effects of solidification process on the bacterial growth and cellulase (CMCase) enzyme activity. Two types of mixing were designed for fibric, hemic and sapric peats; (i) Ordinary Portland cement (OPC) at an equal amount of dry peat, with 25 % of fly ash (FA) and total of coarse particle, a combination of bottom ash and fibre of 22 – 34 %, (ii) fibric peat was using water-to-binder ratio (w/b) = 1, 50% OPC, 25 % bottom ash (BA) and 25 % FA. For hemic and sapric peat, w/b=3 with 50 % OPC and 50 % BA were used. All samples were prepared triplicates, and were cured for 7, 14, 28 and 56 days in a closed container at room temperature. The results revealed that the first mix design giving a continuous strength development. However, the second mix design shows a decreased in strength pattern after day 28. The influence of the environment factors such as alkaline pH, reduction of the water content and peat temperature has no significant on the reduction amount of native microbes in the peat. The microbes survived in the solidified peat but the amount of microbes were found reduced for all types of mixing Fibric Mixed 1 (FM1), Hemic Mixed 1(HM1) and Sapric Mixed 1 (SM1) were having good strength increment for about 330 – 1427 % with enzymatic activity recorded even after D56. Nevertheless, with increase in the strength development through curing days, the enzymatic activities were reduced. For the time being, it can be concluded that the microbes have the ability to adapt with new environment. The reactivity of the microbes relates with the strength of solidified peat.

Correlation of vascular endothelial growth factor with magnetic resonance imaging in chronic subdural hematomas.

PubMed

Li, Fubin; Hua, Cong; Feng, Yan; Yuan, Hongyan; Bie, Li

2017-06-15

Chronic subdural hematoma (CSDH) is an inflammatory angiogenic disease. It is believed that vascular endothelial growth factor (VEGF) plays an important role in pathological CSDH angiogenesis. In this study, magnetic resonance imaging (MRI) results were used to assign 115 primary CSDH patients to four MRI types. The four MRI types are described as follows: type 1 (T1-weighted low, T2-weighted low), type 2 (T1-weighted high, T2-weighted low), type 3 (T1-weighted mixed, T2-weighted mixed), and type 4 (T1-weighted low/high, T2-weighted high). The four MRI types were then correlated with CSDH stage and patient hematoma fluid and serum VEGH concentrations that were measured using an enzyme-linked immunosorbent assay (ELISA). Neurological status was assessed by Markwalder scoring at admission and six-month follow-up. The mean VEGF concentration was significantly higher in CDSH hematoma fluid samples than in patient sera (p<0.01). In unilateral CSDH hematoma fluid samples, VEGF concentration was highest in type 1 (21,613.5±1473.3pg/ml), next highest in type 2 (18,071.8±1737.1pg/ml), lower in type 3, and lowest in type 4 patients (13,153.7±3854.4pg/ml, 7265.7±726.2pg/ml, respectively). High VEGF concentrations strongly correlated with MRI type (unilateral CSDH group r=0.838, bilateral CSDH group r=0.851, p<0.01). Moreover, higher hematoma fluid VEGF concentrations correlated with markedly higher recurrence in type 1 (3/19, 15.8%) vs. type 4 unilateral CSDH patients (1/27, 3.7%). The present study reports a significant correlation between CSDH hematoma fluid VEGF concentration and MRI results. Therefore, MRI results could be used to predict hematoma fluid VEGF concentrations in CSDH patients. Copyright © 2017 Elsevier B.V. All rights reserved.

The Effect of Pre-School Teacher's Sex on Children's Cognitive Growth and Sexual Identity. Final Report.

ERIC Educational Resources Information Center

Mueller, Edward; Cooper, Barbara

This paper presents three research studies. The first study investigated the use of boys' and girls' play areas, each stocked with sex-type toys, by day care children with male, female, or mixed teacher teams. Examined were the sex of play areas users and the effect of sex of teacher team on the structure of play in each play area. The second…

When Information Improves Information Security

NASA Astrophysics Data System (ADS)

Grossklags, Jens; Johnson, Benjamin; Christin, Nicolas

This paper presents a formal, quantitative evaluation of the impact of bounded-rational security decision-making subject to limited information and externalities. We investigate a mixed economy of an individual rational expert and several naïve near-sighted agents. We further model three canonical types of negative externalities (weakest-link, best shot and total effort), and study the impact of two information regimes on the threat level agents are facing.

Effects of two prescribed fires on red maple regeneration across four levels of canopy cover

Treesearch

William W. DeBord; David S. Buckley; Terry L. Sharik; Jason P. Hartman; Jason G. Henning

2011-01-01

Oak species have maintained an important role in eastern U.S. forests for the last 8,000 years. Intense changes in land use and disturbance regimes brought on by European settlement helped oak persist and expand its range through the 1800s. Mixed-oak forests persist as the predominant forest type in present-day eastern forests, but very little oak recruitment into the...

Two-Stage Magma Mixing and Initial Phase of the 1667 Plinian Eruption of Tarumai Volcano

NASA Astrophysics Data System (ADS)

Tomiya, A.; Takeuchi, S.

2009-12-01

Plinian eruptions can eject high-viscosity low-T magma with high crystal content. Several mechanisms have been proposed, such as remobilization by addition of volatile from high-T magma (Bachmann & Bergantz, 2006) and precursory eruption of low-viscosity hybrid magma between low-T and high-T magmas (Pallister et al., 1996; Takeuchi & Nakamura, 2001). We discuss this matter by analysis on a Plinian eruption of Tarumai Volcano. Tarumai (Tarumae) is one of the most active volcanoes in Japan. The 1667 eruption is the first one in historical time after thousands of years of dormancy, and one of the largest eruptions (VEI 5) in the volcano (Soya & Sato, 1980). The major eruptive product, Ta-b pumice, is andesite, consisting of abundant phenocrysts (20-40 %) and rhyolitic glass (Soya, 1971; Furukawa, 1998; Nakagawa et al., 2006). Hiraga & Nakagawa (2000) reported that the bulk rock was homogeneous (SiO2 = 58-62 wt.%) from subunit b8 (lower) to b1 (upper). On the other hand, Takeuchi (2001) found that the bottom layer of b8 (b8-bottom) was more mafic (SiO2 = 56-58 wt.%) and interpreted it as precursory hybrid magma. We analyzed phenocrysts in b8-bottom and other subunits of Ta-b, and compared their compositions and textures. The followings are obtained. Plagioclase: the compositions and textures are similar among the subunits; some phenocrysts are calcic with a homogeneous core of An > 90, whereas most have a complex texture with An 65 to 75. Orthopyroxene/clinopyroxene: the compositions and textures are similar among the subunits; most phenocrysts have a homogeneous core of Mg* 62 to 68 for orthopyroxene and Mg* 70 to 74 for clinopyroxene; those in b8-bottom show reverse zonings. Olivine: there are few phenocrysts and they often coexist with the calcic plagioclase. Magnetite: the compositions are homogeneous (Usp 30 to 34, Mg/Mn 5 to 7; type-1) except for those in b8-bottom; there are two types of phenocrysts in b8-bottom, Usp 30 to 34, Mg/Mn 7 to 9 (type-2) and Usp 23 to 25, Mg/Mn > 10 (type-3) with no type-1 (classification based on Nakagawa et al. (2006)); magnetite inclusions in pyroxene phenocrysts in b8-bottom are, however, type-1. According to the observations, we propose two-stage magma mixing as follows. Prior to the 1667 eruption, there are high-T mafic magma with olivine, calcic plagioclase and type-3 magnetite, and low-T main magma with two pyroxenes, other types of plagioclase and type-1 magnetite (and few ilmenite). The first-stage mixing between the two magmas formed the precursory hybrid magma, but could not prompt the magma to erupt immediately. In the hybrid magma, type-1 and -3 magnetite rehomogenized into type-2 due to rapid cation diffusion, but magnetite inclusions in pyroxene remained type-1. Then, the second-stage mixing between the hybrid magma and the high-T magma occurred, and just after the mixing (with no rehomogenization of type-3 magnetite) the eruption began. Following the hybrid magma (b8-bottom), the main magma erupted. Considering the diffusion coefficients of Ti and Mg in magnetite, the period between the two mixings was several years, whereas the period between the second mixing and the eruption was less than weeks. The two-stage mixing of high-T magma enabled the high-viscosity phenocryst-rich magma to erupt.

A diffuse mixed histiocytic-lymphocytic lymphoma associated with immunological abnormalities.

PubMed

Syrjänen, K J

1979-01-01

A diffuse generalized lymphoma histologically classified as mixed histiocytic-lymphocytic type and associated with profound immunologie abnormalities is reported. The patient had an autoimmune hemolytic anemia, an autoimmune thrombocytopenia, polyclonally increased IgG and IgM, polyclonal secretion of kappa and lamda chains into urine, very low serum complement C3 and antibodies against glomerulus and smooth muscle. When studied with the modern surface-marker techniques, the lesion was found to be composed of entirely lymphoid cells of the B-lymphocyte series. The proper classification of this tumor could be a primitive immunoblastic sarcoma. The relationship of the present tumor to the non-neoplastic angioimmunoblastic lymphadenopathia is discussed. The necessity of applying the surface-marker techniques in the classification of malignant lymphomas is emphasized.

Testicular seminomatous mixed germ cell tumor with choriocarcinoma and teratoma with secondary somatic malignancy: a case report.

PubMed

Aneja, Amandeep; Bhattacharyya, Siddharth; Mydlo, Jack; Inniss, Susan

2014-01-01

Testicular tumors are a heterogeneous group of neoplasms exhibiting diverse histopathology and can be classified as seminomatous and non-seminomatous germ cell tumor types. Mixed germ cell tumors contain more than one germ cell component and various combinations have been reported. Here, we present a rare case of a mixed germ cell tumor composed of seminoma, choriocarcinoma and teratoma with a secondary somatic malignancy. A 31-year-old Caucasian man presented with splenic rupture to our hospital. A right-sided testicular swelling had been present for 6 months and his alpha-fetoprotein, beta-human chorionic gonadotropin, and lactose dehydrogenase were increased. An ultrasound of his scrotum revealed an enlarged right testis with heterogeneous echogenicity. Multiple hypervascular lesions were noted in his liver and spleen. He underwent transcatheter embolization therapy of his splenic artery followed by splenectomy and right-sided orchiectomy. A computed tomography scan also showed metastasis to both lungs. During his last follow up after four cycles of cisplatin-based chemotherapy, the level of tumor markers had decreased, decreases in the size of his liver and pulmonary lesions were noted but new sclerotic lesions were evident in his thoracolumbar region raising concern for bony metastasis. Prognosis of testicular tumor depends mainly on the clinical stage, but emergence of a sarcomatous component presents a challenge in the treatment of germ cell tumors and the histological subtype of this component can be used as a guide to specific chemotherapy in these patients.

Characterization of vertical mixing in oscillatory vegetated flows

NASA Astrophysics Data System (ADS)

Abdolahpour, M.; Ghisalberti, M.; Lavery, P.; McMahon, K.

2016-02-01

Seagrass meadows are primary producers that provide important ecosystem services, such as improved water quality, sediment stabilisation and trapping and recycling of nutrients. Most of these ecological services are strongly influenced by the vertical exchange of water across the canopy-water interface. That is, vertical mixing is the main hydrodynamic process governing the large-scale ecological and environmental impact of seagrass meadows. The majority of studies into mixing in vegetated flows have focused on steady flow environments whereas many coastal canopies are subjected to oscillatory flows driven by surface waves. It is known that the rate of mass transfer will vary greatly between unidirectional and oscillatory flows, necessitating a specific investigation of mixing in oscillatory canopy flows. In this study, we conducted an extensive laboratory investigation to characterise the rate of vertical mixing through a vertical turbulent diffusivity (Dt,z). This has been done through gauging the evolution of vertical profiles of concentration (C) of a dye sheet injected into a wave-canopy flow. Instantaneous measurement of the variance of the vertical concentration distribution ( allowed the estimation of a vertical turbulent diffusivity (). Two types of model canopies, rigid and flexible, with identical heights and frontal areas, were subjected to a wide and realistic range of wave height and period. The results showed two important mechanisms that dominate vertical mixing under different conditions: a shear layer that forms at the top of the canopy and wake turbulence generated by the stems. By allowing a coupled contribution of wake and shear layer mixing, we present a relationship that can be used to predict the rate of vertical mixing in coastal canopies. The results further showed that the rate of vertical mixing within flexible vegetation was always lower than the corresponding rigid canopy, confirming the impact of plant flexibility on canopy-flow interactions.

Mixed-linker strategy for the construction of multifunctional metal–organic frameworks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qin, Jun-Sheng; Yuan, Shuai; Wang, Qi

2017-01-01

Mixed-linker strategy is a promising way to construct multifunctional metal–organic frameworks (MOFs). In this review, we demonstrate the recent developments, discussions and challenges related to the preparation and applications of four types of mixed-linker MOF materials.

The impact of mixed solvents on the complexation thermodynamics of Eu(III) by simple carboxylate and amino carboxylate ligands

DOE PAGES

Felmy, Heather M.; Bennett, Kevin T.; Clark, Sue B.

2017-05-12

To gain insight on the role of mixed solvents on the thermodynamic driving forces for the complexation between trivalent f-elements and organic ligands, solution phase thermodynamic parameters were determined for Eu(III) complexation with 2-hydroxyisobutyric acid (HIBA) and 2-aminoisobutyric acid (AIBA) in mixed methanol (MeOH)-water and N,N-dimethylformamide (DMF)-water solvents. Included in this study were the determination of mixed solvent autoprotolysis constants (pK α) as well as the thermodynamic formation constants: log β, ΔG, ΔH, and ΔS, for ligand protonation and Eu(III)-ligand complexation utilizing potentiometry and calorimetry techniques. The results presented are conditional thermodynamic values determined at an ionic strength of 1.0more » M NaClO 4 and a temperature of 298 K. It was found that moving from an aqueous solution to a binary aqueous-organic solvent affected all solution equilibria to some degree and that the extent of change depended on both the type of mixed solvent and the ligand in each study. Here, the ability to understand and predict these changes in thermodynamic values as a function of solvent composition provides important information about the chemistry of the trivalent f-elements.« less

Relapse, re-infection and mixed infections in tuberculosis disease.

PubMed

McIvor, Amanda; Koornhof, Hendrik; Kana, Bavesh Davandra

2017-04-01

Tuberculosis (TB) disease can be characterized by genotypic and phenotypic complexity in Mycobacterium tuberculosis bacilli within a single patient. This microbiological heterogeneity has become an area of intense study due its perceived importance in drug tolerance, drug resistance and as a surrogate measure of transmission rates. This review presents a descriptive analysis of research describing the prevalence of mixed-strain TB infections in geographically distinct locations. Despite significant variation in disease burden and a rampant human immunodeficiency virus (HIV)-TB co-epidemic, there was no difference in the prevalence range of mixed infections reported in African countries when compared to the rest of the world. The occurrence of recurrent TB was associated with a higher prevalence of mixed-strain infections, but this difference was not reported as statistically significant. These interpretations were limited by differences in the design and overall size of the studies assessed. Factors such as sputum quality, culture media, number of repeated culture steps, molecular typing methods and HIV-infection status can affect the detection of mixed-strain infection. It is recommended that future clinical studies should focus on settings with varying TB burdens, with a common sample processing protocol to gain further insight into these phenomena and develop novel transmission blocking strategies. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The impact of mixed solvents on the complexation thermodynamics of Eu(III) by simple carboxylate and amino carboxylate ligands

DOE Office of Scientific and Technical Information (OSTI.GOV)

Felmy, Heather M.; Bennett, Kevin T.; Clark, Sue B.

To gain insight on the role of mixed solvents on the thermodynamic driving forces for the complexation between trivalent f-elements and organic ligands, solution phase thermodynamic parameters were determined for Eu(III) complexation with 2-hydroxyisobutyric acid (HIBA) and 2-aminoisobutyric acid (AIBA) in mixed methanol (MeOH)-water and N,N-dimethylformamide (DMF)-water solvents. Included in this study were the determination of mixed solvent autoprotolysis constants (pK α) as well as the thermodynamic formation constants: log β, ΔG, ΔH, and ΔS, for ligand protonation and Eu(III)-ligand complexation utilizing potentiometry and calorimetry techniques. The results presented are conditional thermodynamic values determined at an ionic strength of 1.0more » M NaClO 4 and a temperature of 298 K. It was found that moving from an aqueous solution to a binary aqueous-organic solvent affected all solution equilibria to some degree and that the extent of change depended on both the type of mixed solvent and the ligand in each study. Here, the ability to understand and predict these changes in thermodynamic values as a function of solvent composition provides important information about the chemistry of the trivalent f-elements.« less

Bayesian mixture analysis for metagenomic community profiling.

PubMed

Morfopoulou, Sofia; Plagnol, Vincent

2015-09-15

Deep sequencing of clinical samples is now an established tool for the detection of infectious pathogens, with direct medical applications. The large amount of data generated produces an opportunity to detect species even at very low levels, provided that computational tools can effectively profile the relevant metagenomic communities. Data interpretation is complicated by the fact that short sequencing reads can match multiple organisms and by the lack of completeness of existing databases, in particular for viral pathogens. Here we present metaMix, a Bayesian mixture model framework for resolving complex metagenomic mixtures. We show that the use of parallel Monte Carlo Markov chains for the exploration of the species space enables the identification of the set of species most likely to contribute to the mixture. We demonstrate the greater accuracy of metaMix compared with relevant methods, particularly for profiling complex communities consisting of several related species. We designed metaMix specifically for the analysis of deep transcriptome sequencing datasets, with a focus on viral pathogen detection; however, the principles are generally applicable to all types of metagenomic mixtures. metaMix is implemented as a user friendly R package, freely available on CRAN: http://cran.r-project.org/web/packages/metaMix sofia.morfopoulou.10@ucl.ac.uk Supplementary data are available at Bionformatics online. © The Author 2015. Published by Oxford University Press.

Dynamic autoinoculation and the microbial ecology of a deep water hydrocarbon irruption

PubMed Central

Valentine, David L.; Mezić, Igor; Maćešić, Senka; Črnjarić-Žic, Nelida; Ivić, Stefan; Hogan, Patrick J.; Fonoberov, Vladimir A.; Loire, Sophie

2012-01-01

The irruption of gas and oil into the Gulf of Mexico during the Deepwater Horizon event fed a deep sea bacterial bloom that consumed hydrocarbons in the affected waters, formed a regional oxygen anomaly, and altered the microbiology of the region. In this work, we develop a coupled physical–metabolic model to assess the impact of mixing processes on these deep ocean bacterial communities and their capacity for hydrocarbon and oxygen use. We find that observed biodegradation patterns are well-described by exponential growth of bacteria from seed populations present at low abundance and that current oscillation and mixing processes played a critical role in distributing hydrocarbons and associated bacterial blooms within the northeast Gulf of Mexico. Mixing processes also accelerated hydrocarbon degradation through an autoinoculation effect, where water masses, in which the hydrocarbon irruption had caused blooms, later returned to the spill site with hydrocarbon-degrading bacteria persisting at elevated abundance. Interestingly, although the initial irruption of hydrocarbons fed successive blooms of different bacterial types, subsequent irruptions promoted consistency in the structure of the bacterial community. These results highlight an impact of mixing and circulation processes on biodegradation activity of bacteria during the Deepwater Horizon event and suggest an important role for mixing processes in the microbial ecology of deep ocean environments. PMID:22233808

Individual Aerosol Particles from Biomass Burning in Southern Africa. 1; Compositions and Size Distributions of Carbonaceous Particles

NASA Technical Reports Server (NTRS)

Posfai, Mihaly; Simonics, Renata; Li, Jia; Hobbs, Peter V.; Buseck, Peter R.

2003-01-01

Individual aerosol particles in smoke plumes from biomass fires and in regional hazes in southern Africa were studied using analytical transmission electron microscopy (TEM), which allowed detailed characterization of carbonaceous particle types in smoke and determination of changes in particle properties and concentrations during smoke aging. Based on composition, morphology, and microstructure, three distinct types of carbonaceous particles were present in the smoke: organic particles with inorganic (K-salt) inclusions, tar ball particles, and soot. The relative number concentrations of organic particles were largest in young smoke, whereas tar balls were dominant in a slightly aged (1 hour) smoke from a smoldering fire. Flaming fires emitted relatively more soot particles than smoldering fires, but soot was a minor constituent of all studied plumes. Further aging caused the accumulation of sulfate on organic and soot particles, as indicated by the large number of internally mixed organic/sulfate and soot/sulfate particles in the regional haze. Externally mixed ammonium sulfate particles dominated in the boundary layer hazes, whereas organic/sulfate particles were the most abundant type in the upper hazes. Apparently, elevated haze layers were more strongly affected by biomass smoke than those within the boundary layer. Based on size distributions and the observed patterns of internal mixing, we hypothesize that organic and soot particles are the cloud-nucleating constituents of biomass smoke aerosols. Sea-salt particles dominated in the samples taken in stratus clouds over the Atlantic Ocean, off the coast of Namibia, whereas a distinct haze layer above the clouds consisted of aged biomass smoke particles.

Student attitudes towards socially acceptable and unacceptable group working practices.

PubMed

Underwood, Jean D M

2003-08-01

While there is much support for co-operative learning among learning theorists, not all learners exhibit the same enthusiasm for groupwork. A number of factors such as sex, group size and ability mix, subject domain, task type and organization have been shown to influence the effectiveness of co-operative and collaborative learning. This study established learners' attitudes to various shared working scenarios. In this mixed design, 140 post-graduate teacher trainees were asked to imagine their responses to seven groupwork scenarios presented as a series of short vignettes. The vignettes varied on the degree of co-operation required; the sex of the prospective co-worker(s) including single and mixed-sex groups; type of assessment, including no assessment at all; and on academically acceptable and unacceptable 'shared' working practices. Anticipated attitudinal and behavioural responses of the students were assessed by questionnaire. On the whole, students were cautiously willing to be involved in groupwork. There were caveats, however. Factors such as the characteristics of the group members, the level and type of assessment procedures in operation, and individual differences, including sex and self-reported social deviance, also governed their responses. There was very limited agreement to be involved in socially undesirable collaborative group activities at a personal level or to condone such activities by others. Those students who showed a tendency towards mild anti-social behaviour were more willing to take direct punitive action against non-contributors than their peers. Female students were more willing to invoke the help of the tutor than their male counterparts, but only if the anti-social behaviour impacted on them personally.

Properties of Non-Structural Concrete Made with Mixed Recycled Aggregates and Low Cement Content

PubMed Central

López-Uceda, Antonio; Ayuso, Jesús; López, Martin; Jimenez, José Ramón; Agrela, Francisco; Sierra, María José

2016-01-01

In spite of not being legally accepted in most countries, mixed recycled aggregates (MRA) could be a suitable raw material for concrete manufacturing. The aims of this research were as follows: (i) to analyze the effect of the replacement ratio of natural coarse aggregates with MRA, the amount of ceramic particles in MRA, and the amount of cement, on the mechanical and physical properties of a non-structural concrete made with a low cement content; and (ii) to verify if it is possible to achieve a low-strength concrete that replaces a greater amount of natural aggregate with MRA and that has a low cement content. Two series of concrete mixes were manufactured using 180 and 200 kg/m3 of CEM II/A-V 42.5 R type Portland cement. Each series included seven concrete mixes: one with natural aggregates; two MRA with different ceramic particle contents; and one for each coarse aggregate replacement ratio (20%, 40%, and 100%). To study their properties, compressive and splitting tensile strength, modulus of elasticity, density, porosity, water penetration, and sorptivity, tests were performed. The results confirmed that the main factors affecting the properties analyzed in this research are the amount of cement and the replacement ratio; the two MRAs used in this work presented a similar influence on the properties. A non-structural, low-strength concrete (15 MPa) with an MRA replacement ratio of up to 100% for 200 kg/m3 of cement was obtained. This type of concrete could be applied in the construction of ditches, sidewalks, and other similar civil works. PMID:28787874

Properties of Non-Structural Concrete Made with Mixed Recycled Aggregates and Low Cement Content.

PubMed

López-Uceda, Antonio; Ayuso, Jesús; López, Martin; Jimenez, José Ramón; Agrela, Francisco; Sierra, María José

2016-01-26

In spite of not being legally accepted in most countries, mixed recycled aggregates (MRA) could be a suitable raw material for concrete manufacturing. The aims of this research were as follows: (i) to analyze the effect of the replacement ratio of natural coarse aggregates with MRA, the amount of ceramic particles in MRA, and the amount of cement, on the mechanical and physical properties of a non-structural concrete made with a low cement content; and (ii) to verify if it is possible to achieve a low-strength concrete that replaces a greater amount of natural aggregate with MRA and that has a low cement content. Two series of concrete mixes were manufactured using 180 and 200 kg/m³ of CEM II/A-V 42.5 R type Portland cement. Each series included seven concrete mixes: one with natural aggregates; two MRA with different ceramic particle contents; and one for each coarse aggregate replacement ratio (20%, 40%, and 100%). To study their properties, compressive and splitting tensile strength, modulus of elasticity, density, porosity, water penetration, and sorptivity, tests were performed. The results confirmed that the main factors affecting the properties analyzed in this research are the amount of cement and the replacement ratio; the two MRAs used in this work presented a similar influence on the properties. A non-structural, low-strength concrete (15 MPa) with an MRA replacement ratio of up to 100% for 200 kg/m³ of cement was obtained. This type of concrete could be applied in the construction of ditches, sidewalks, and other similar civil works.

Evaluation of magma mixing in the subvolcanic rocks of Ghansura Felsic Dome of Chotanagpur Granite Gneiss Complex, eastern India

NASA Astrophysics Data System (ADS)

Gogoi, Bibhuti; Saikia, Ashima; Ahmad, Mansoor; Ahmad, Talat

2018-06-01

The subvolcanic rocks exposed in the Ghansura Felsic Dome (GFD) of the Bathani volcano-sedimentary sequence at the northern fringe of the Rajgir fold belt in the Proterozoic Chotanagpur Granite Gneiss Complex preserves evidence of magma mixing and mingling in mafic (dolerite), felsic (microgranite) and intermediate (hybrid) rocks. Structures like crenulated margins of mafic enclaves, felsic microgranular enclaves and ocelli with reaction surfaces in mafic rocks, hybrid zones at mafic-felsic contacts, back-veining and mafic flows in the granitic host imply magma mingling phenomena. Textural features like quartz and titanite ocelli, acicular apatite, rapakivi and anti-rapakivi feldspar intergrowths, oscillatory zoned plagioclase, plagioclase with resorbed core and intact rim, resorbed crystals, mafic clots and mineral transporting veins are interpreted as evidence of magma mixing. Three distinct hybridized rocks have formed due to varied interactions of the intruding mafic magma with the felsic host, which include porphyritic diorite, mingled rocks and intermediate rocks containing felsic ocelli. Geochemical signatures confirm that the hybrid rocks present in the study area are mixing products formed due to the interaction of mafic and felsic magmas. Physical parameters like temperature, viscosity, glass transition temperature and fragility calculated for different rock types have been used to model the relative contributions of mafic and felsic end-member magmas in forming the porphyritic diorite. From textural and geochemical investigations it appears that the GFD was a partly solidified magma chamber when mafic magma intruded it leading to the formation of a variety of hybrid rock types.

Assessing oral candidal carriage with mixed salivary glucose levels as non-invasive diagnostic tool in type-2 diabetics of davangere, karnataka, India.

PubMed

Naik, Rashmi; Mujib B R, Ahmed; Raaju, U R; Telagi, Neethu

2014-07-01

The health of oral tissues is known to be related to salivary flow and its composition which may be altered in diabetic patients. The purpose of this study is to correlate mixed salivary glucose levels and oral candidal carriage and to assess the prevalence of candidal carriage in diabetics and controls. Thirty adults with type-2 diabetes and 30 without diabetes (control subjects), aged 30-60 yr, participated in the study. Unstimulated saliva was collected and investigated for glucose levels (using glucose oxidase method) and colony-forming units (CFU) of Candida, this was stained with two stains, periodic acid-schiff stain and Grocott Gomori stain. In the present study mixed salivary glucose concentration in diabetics was significantly higher (p<0.01) compared to the controls. Diabetics with intraoral candidal carriage had higher salivary glucose levels (mean = 12.76±5.85 mg/dl) compared to cases where Candida was not isolated. The diabetics without intraoral candidal carriage had lower salivary glucose levels (mean = 5.36±2.24 mg/dl). This relationship could be seen in controls (non-diabetics) also. Diabetics showed an oral candidal carriage rate of 80% which was significantly higher compared to nondiabetics who showed an oral candidal carriage rate of 40%. Mixed salivary glucose levels were significantly higher in diabetics. The possible high salivary glucose level could predispose to oral candidal infection. So saliva can be used as a quick, non-invasive tool to assess the oral candidal status and possible infection.

Development of a floating photobioreactor with internal partitions for efficient utilization of ocean wave into improved mass transfer and algal culture mixing.

PubMed

Kim, Z-Hun; Park, Hanwool; Hong, Seong-Joo; Lim, Sang-Min; Lee, Choul-Gyun

2016-05-01

Culturing microalgae in the ocean has potentials that may reduce the production cost and provide an option for an economic biofuel production from microalgae. The ocean holds great potentials for mass microalgal cultivation with its high specific heat, mixing energy from waves, and large cultivable area. Suitable photobioreactors (PBRs) that are capable of integrating marine energy into the culture systems need to be developed for the successful ocean cultivation. In this study, prototype floating PBRs were designed and constructed using transparent low-density polyethylene film for microalgal culture in the ocean. To improve the mixing efficiency, various types of internal partitions were introduced within PBRs. Three different types of internal partitions were evaluated for their effects on the mixing efficiency in terms of mass transfer (k(L)a) and mixing time in the PBRs. The partition type with the best mixing efficiency was selected, and the number of partitions was varied from one to three for investigation of its effect on mixing efficiency. When the number of partitions is increased, mass transfer increased in proportion to the number of partitions. However, mixing time was not directly related to the number of partitions. When a green microalga, Tetraselmis sp. was cultivated using PBRs with the selected partition under semi-continuous mode in the ocean, biomass and fatty acid productivities in the PBRs were increased by up to 50 % and 44% at high initial cell density, respectively, compared to non-partitioned ones. The results of internally partitioned PBRs demonstrated potentials for culturing microalgae by efficiently utilizing ocean wave energy into culture mixing in the ocean.

Conversion of Syngas-Derived C2+ Mixed Oxygenates to C3-C5 Olefins over ZnxZryOz Mixed Oxides Catalysts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Colin D.; Lebarbier, Vanessa M.; Flake, Matthew D.

2016-04-01

In this study we report on a ZnxZryOz mixed oxide type catalyst capable of converting a syngas-derived C2+ mixed oxygenate feedstock to isobutene-rich olefins. Aqueous model feed comprising of ethanol, acetaldehyde, acetic acid, ethyl acetate, methanol, and propanol was used as representative liquid product derived from a Rh-based mixed oxygenate synthesis catalyst. Greater than 50% carbon yield to C3-C5 mixed olefins was demonstrated when operating at 400-450oC and 1 atm. In order to rationalize formation of the products observed feed components were individually evaluated. Major constituents of the feed mixture (ethanol, acetaldehyde, acetic acid, and ethyl acetate) were found tomore » produce isobutene-rich olefins. C-C coupling was also demonstrated for propanol feedstock - a minor constituent of the mixed oxygenate feed - producing branched C6 olefins, revealing scalability to alcohols higher than ethanol following an analogous reaction pathway. Using ethanol and propanol feed mixtures, cross-coupling reactions produced mixtures of C4, C5, and C6 branched olefins. The presence of H2 in the feed was found to facilitate hydrogenation of the ketone intermediates, thus producing straight chain olefins as byproducts. While activity loss from coking is observed complete catalyst regeneration is achieved by employing mild oxidation. For conversion of the mixed oxygenate feed a Zr/Zn ratio of 2.5 and a reaction temperature of 450oC provides the best balance of stability, activity, and selectivity. X-ray diffraction and scanning transmission electron microscopy analysis reveals the presence of primarily cubic phase ZrO2 and a minor amount of the monoclinic phase, with ZnO being highly dispersed in the lattice. The presence of ZnO appears to stabilize the cubic phase resulting in less monoclinic phase as the ZnO concentration increases. Infrared spectroscopy shows the mixed oxide acid sites are characterized as primarily Lewis type acidity. The direct relationship between isobutene production and the ratio of basic/acidic sites was demonstrated. An optimized balance of active sites for isobutene production from acetone was obtained with a basic/acidic site ratio of ~2. This technology for the conversion of aqueous mixtures of C2+ mixed oxygenates provides significant advantages over other presently studied catalysts in that its unique properties permit the utilization of a variety of feeds in a consistently selective manner.« less

An AERONET-Based Aerosol Classification Using the Mahalanobis Distance

NASA Technical Reports Server (NTRS)

Hamill, Patrick; Giordano, Marco; Ward, Carolyne; Giles, David; Holben, Brent

2016-01-01

We present an aerosol classification based on AERONET aerosol data from 1993 to 2012. We used the AERONET Level 2.0 almucantar aerosol retrieval products to define several reference aerosol clusters which are characteristic of the following general aerosol types: Urban-Industrial, Biomass Burning, Mixed Aerosol, Dust, and Maritime. The classification of a particular aerosol observation as one of these aerosol types is determined by its five-dimensional Mahalanobis distance to each reference cluster. We have calculated the fractional aerosol type distribution at 190 AERONET sites, as well as the monthly variation in aerosol type at those locations. The results are presented on a global map and individually in the supplementary material. Our aerosol typing is based on recognizing that different geographic regions exhibit characteristic aerosol types. To generate reference clusters we only keep data points that lie within a Mahalanobis distance of 2 from the centroid. Our aerosol characterization is based on the AERONET retrieved quantities, therefore it does not include low optical depth values. The analysis is based on point sources (the AERONET sites) rather than globally distributed values. The classifications obtained will be useful in interpreting aerosol retrievals from satellite borne instruments.

A New Item Selection Procedure for Mixed Item Type in Computerized Classification Testing.

ERIC Educational Resources Information Center

Lau, C. Allen; Wang, Tianyou

This paper proposes a new Information-Time index as the basis for item selection in computerized classification testing (CCT) and investigates how this new item selection algorithm can help improve test efficiency for item pools with mixed item types. It also investigates how practical constraints such as item exposure rate control, test…

Generalized Path Analysis and Generalized Simultaneous Equations Model for Recursive Systems with Responses of Mixed Types

ERIC Educational Resources Information Center

Tsai, Tien-Lung; Shau, Wen-Yi; Hu, Fu-Chang

2006-01-01

This article generalizes linear path analysis (PA) and simultaneous equations models (SiEM) to deal with mixed responses of different types in a recursive or triangular system. An efficient instrumental variable (IV) method for estimating the structural coefficients of a 2-equation partially recursive generalized path analysis (GPA) model and…

Concrete Mixing Methods and Concrete Mixers: State of the Art

PubMed Central

Ferraris, Chiara F.

2001-01-01

As for all materials, the performance of concrete is determined by its microstructure. Its microstructure is determined by its composition, its curing conditions, and also by the mixing method and mixer conditions used to process the concrete. This paper gives an overview of the various types of mixing methods and concrete mixers commercially available used by the concrete industry. There are two main types of mixers used: batch mixers and continuous mixers. Batch mixers are the most common. To determine the mixing method best suited for a specific application, factors to be considered include: location of the construction site (distance from the batching plant), the amount of concrete needed, the construction schedule (volume of concrete needed per hour), and the cost. Ultimately, the quality of the concrete produced determines its performance after placement. An important measure of the quality is the homogeneity of the material after mixing. This paper will review mixing methods in regards to the quality of the concrete produced. Some procedures used to determine the effectiveness of the mixing will be examined. PMID:27500029

Renormalisation group corrections to neutrino mixing sum rules

NASA Astrophysics Data System (ADS)

Gehrlein, J.; Petcov, S. T.; Spinrath, M.; Titov, A. V.

2016-11-01

Neutrino mixing sum rules are common to a large class of models based on the (discrete) symmetry approach to lepton flavour. In this approach the neutrino mixing matrix U is assumed to have an underlying approximate symmetry form Ũν, which is dictated by, or associated with, the employed (discrete) symmetry. In such a setup the cosine of the Dirac CP-violating phase δ can be related to the three neutrino mixing angles in terms of a sum rule which depends on the symmetry form of Ũν. We consider five extensively discussed possible symmetry forms of Ũν: i) bimaximal (BM) and ii) tri-bimaximal (TBM) forms, the forms corresponding to iii) golden ratio type A (GRA) mixing, iv) golden ratio type B (GRB) mixing, and v) hexagonal (HG) mixing. For each of these forms we investigate the renormalisation group corrections to the sum rule predictions for δ in the cases of neutrino Majorana mass term generated by the Weinberg (dimension 5) operator added to i) the Standard Model, and ii) the minimal SUSY extension of the Standard Model.

Petrochemical evolution of the White Mfolozi Granite pluton: Evidence for a late Palaeoarchaean A-type granite from the SE Kaapvaal Craton, South Africa

NASA Astrophysics Data System (ADS)

Misra, Saumitra; Reinhardt, Jürgen; Wilson, Allan H.

2017-08-01

One of the major limitations in understanding the geochemical evolution of the Kaapvaal Craton, South Africa, is the scarcity of whole rock trace element data of the granitoid and other rocks compared to the vastness of this cratonic block. Here we present new XRF major oxide and ICP-MS trace element analyses of the White Mfolozi Granitoid (WMG) pluton, SE Kaapvaal Craton, which suggest that the 3.25 Ga (U-Pb zircon age) old WMG pluton is a peraluminous A-type granite and could be equivalent to the intrusive potassic granite phase of the Anhalt Granitoid suite, occurring to the North of the WMG pluton. The pluton was generated by batch partial melting of a pre-existing TTG source in two major phases under relatively anhydrous conditions, and the heat of partial melting could have been provided by a voluminous mantle-derived mafic magma, which intruded into mid-crustal levels (c. 17 km), perhaps during a period of crustal extension. The estimated pressure and temperature of generation of the WMG parent magma with average molar [or/(or + ab)] 0.48 could be 500 MPa and close to 1000 °C, respectively, when compared with the results of experimental petrology. Interstitial occurrence of relatively iron-rich biotite [Mg/(Mg + Fe) 0.41-0.45] suggests that the final temperature of crystallization of the pluton was close to 800 °C. An important magmatic event following the main phase of partial melting was limited mixing between the intrusive mafic magma and co-existing newly generated granitic melt. This magma mixing resulted in distinct variations in SiO2 and a low initial Sr isotopic ratio (0.7013) of the WMG pluton. Although both the models of partial melting of quartzo-feldspathic sources and fractional crystallization of basaltic magmas with or without crustal assimilation have been proposed for the origin of A-type granites, the model of magmatic evolution of the WMG pluton presented here can also be an alternative model for the generation of A-type granites. In this model, post-partial melting magma mixing is perhaps critical in explaining the Daly gap in composition and extreme variations in chemical (e.g., SiO2) and isotopic compositions observed in many bimodal A-type granite suites. The emplacement of the oldest known A-type granitoid suite in the Kaapvaal Craton, the WMG pluton, marks a period of stabilization of the craton before erosion and deposition of the overlying volcano-sedimentary succession of the Pongola Supergroup.

Experimental Testing and Modeling Analysis of Solute Mixing at Water Distribution Pipe Junctions

EPA Science Inventory

Flow dynamics at a pipe junction controls particle trajectories, solute mixing and concentrations in downstream pipes. Here we have categorized pipe junctions into five hydraulic types, for which flow distribution factors and analytical equations for describing the solute mixing ...

On the optimization of a mixed speaker array in an enclosed space using the virtual-speaker weighting method

NASA Astrophysics Data System (ADS)

Peng, Bo; Zheng, Sifa; Liao, Xiangning; Lian, Xiaomin

2018-03-01

In order to achieve sound field reproduction in a wide frequency band, multiple-type speakers are used. The reproduction accuracy is not only affected by the signals sent to the speakers, but also depends on the position and the number of each type of speaker. The method of optimizing a mixed speaker array is investigated in this paper. A virtual-speaker weighting method is proposed to optimize both the position and the number of each type of speaker. In this method, a virtual-speaker model is proposed to quantify the increment of controllability of the speaker array when the speaker number increases. While optimizing a mixed speaker array, the gain of the virtual-speaker transfer function is used to determine the priority orders of the candidate speaker positions, which optimizes the position of each type of speaker. Then the relative gain of the virtual-speaker transfer function is used to determine whether the speakers are redundant, which optimizes the number of each type of speaker. Finally the virtual-speaker weighting method is verified by reproduction experiments of the interior sound field in a passenger car. The results validate that the optimum mixed speaker array can be obtained using the proposed method.

First Principles Calculations of Transition Metal Binary Alloys: Phase Stability and Surface Effects

NASA Astrophysics Data System (ADS)

Aspera, Susan Meñez; Arevalo, Ryan Lacdao; Shimizu, Koji; Kishida, Ryo; Kojima, Kazuki; Linh, Nguyen Hoang; Nakanishi, Hiroshi; Kasai, Hideaki

2017-06-01

The phase stability and surface effects on binary transition metal nano-alloy systems were investigated using density functional theory-based first principles calculations. In this study, we evaluated the cohesive and alloying energies of six binary metal alloy bulk systems that sample each type of alloys according to miscibility, i.e., Au-Ag and Pd-Ag for the solid solution-type alloys (SS), Pd-Ir and Pd-Rh for the high-temperature solid solution-type alloys (HTSS), and Au-Ir and Ag-Rh for the phase-separation (PS)-type alloys. Our results and analysis show consistency with experimental observations on the type of materials in the bulk phase. Varying the lattice parameter was also shown to have an effect on the stability of the bulk mixed alloy system. It was observed, particularly for the PS- and HTSS-type materials, that mixing gains energy from the increasing lattice constant. We furthermore evaluated the surface effects, which is an important factor to consider for nanoparticle-sized alloys, through analysis of the (001) and (111) surface facets. We found that the stability of the surface depends on the optimization of atomic positions and segregation of atoms near/at the surface, particularly for the HTSS and the PS types of metal alloys. Furthermore, the increase in energy for mixing atoms at the interface of the atomic boundaries of PS- and HTSS-type materials is low enough to overcome by the gain in energy through entropy. These, therefore, are the main proponents for the possibility of mixing alloys near the surface.

[Diagnosis and surgical treatment of Castleman's disease].

PubMed

Ma, Shi-hong; Liu, Qin-jiang; Zhang, You-cheng; Yang, Rong

2011-04-26

To explore the clinical features and surgical treatment of tumors associated with Castleman's disease (CD). The clinical profiles of 19 patients with neck giant lymph node hyperplasia were analyzed retrospectively. There were 8 males and 11 females with a median age of 40 years old (range: 7 - 74). The tumor locations were neck (n = 12), neck & mediastinal cavity (n = 2), axillary fossa (n = 2), retroperitoneal area (n = 2) and abdominal cavity (n = 1). Eighteen of them underwent surgical resection of tumor or lymph nodes. All were diagnosed as CD by pathological examinations. There were 16 localized CD (LCD) including hyaline vascular type (HV type, n = 11), mixed type (mix type, n = 4) and plasma cell type-Hodgkin's disease (n = 1). Among 3 multicentric CD (MCD), there were 2 case of plasma cell type (PC type) and 1 case of mixed type (mix type). Long-term survival was achieved in 19 cases among which 1 case of plasma cell type MCD survived for 5 years and underwent a second operation and postoperative chemotherapy of CVP (cyclophosphamide, vincristine & prednisone) regimen for 3 cycles due to recurrence in 2 years and 1 case of plasma cell type LCD-Hodgkin's disease survived for 15 months and underwent a second operation and postoperative chemotherapy of ABVD (adriamycin, bleomycin, vinblastine & dacarbazine)regimen for 6 cycles due to recurrence in 6 months. One case of plasma cell type MCD in abdominal cavity on chemotherapy of CHOP (cyclophosphamide, hydroxydaunorubicin, vincristine & prednisone) regimen for 6 cycles was discharged after a successful management of intestinal obstruction. The major clinical symptom of CD is a gradually enlarging painless mass. Surgical resection of tumor remains the first-line treatment for localized CD and the prognosis is excellent. Multicentric and plasma cell type CDs are prone to recurrence and transformation to lymphoma. And their first-line therapeutic should encompass multi-modality regimens of surgery and adjuvant chemotherapy. However, the clinical prognosis is still poor.

Behavioral responses of silverback gorillas (Gorilla gorilla gorilla) to videos.

PubMed

Maloney, Margaret A; Leighty, Katherine A; Kuhar, Christopher W; Bettinger, Tamara L

2011-01-01

This study examined the impact of video presentations on the behavior of 4 silverback, western lowland gorillas (Gorilla gorilla gorilla). On each of 5 occasions, gorillas viewed 6 types of videos (blue screen, humans, an all-male or mixed-sex group engaged in low activity, and an all-male or mixed-sex group engaged in agonistic behavior). The study recorded behavioral responses and watching rates. All gorillas preferred dynamic over static videos; 3 watched videos depicting gorillas significantly more than those depicting humans. Among the gorilla videos, the gorillas clearly preferred watching the mixed-sex group engaged in agonistic behavior; yet, this did not lead to an increase in aggression or behavior indicating agitation. Further, habituation to videos depicting gorillas did not occur. This supports the effectiveness of this form of enrichment, particularly for a nonhuman animal needing to be separated temporarily due to illness, shipment quarantine, social restructuring, or exhibit modification. Copyright © The Walt Disney Company®

Discontinuous dual-primal mixed finite elements for elliptic problems

NASA Technical Reports Server (NTRS)

Bottasso, Carlo L.; Micheletti, Stefano; Sacco, Riccardo

2000-01-01

We propose a novel discontinuous mixed finite element formulation for the solution of second-order elliptic problems. Fully discontinuous piecewise polynomial finite element spaces are used for the trial and test functions. The discontinuous nature of the test functions at the element interfaces allows to introduce new boundary unknowns that, on the one hand enforce the weak continuity of the trial functions, and on the other avoid the need to define a priori algorithmic fluxes as in standard discontinuous Galerkin methods. Static condensation is performed at the element level, leading to a solution procedure based on the sole interface unknowns. The resulting family of discontinuous dual-primal mixed finite element methods is presented in the one and two-dimensional cases. In the one-dimensional case, we show the equivalence of the method with implicit Runge-Kutta schemes of the collocation type exhibiting optimal behavior. Numerical experiments in one and two dimensions demonstrate the order accuracy of the new method, confirming the results of the analysis.

Spectra of turbulent static pressure fluctuations in jet mixing layers

NASA Technical Reports Server (NTRS)

Jones, B. G.; Adrian, R. J.; Nithianandan, C. K.; Planchon, H. P., Jr.

1977-01-01

Spectral similarity laws are derived for the power spectra of turbulent static pressure fluctuations by application of dimensional analysis in the limit of large turbulent Reynolds number. The theory predicts that pressure spectra are generated by three distinct types of interaction in the velocity fields: a fourth order interaction between fluctuating velocities, an interaction between the first order mean shear and the third order velocity fluctuations, and an interaction between the second order mean shear rate and the second order fluctuating velocity. Measurements of one-dimensional power spectra of the turbulent static pressure fluctuations in the driven mixing layer of a subsonic, circular jet are presented, and the spectra are examined for evidence of spectral similarity. Spectral similarity is found for the low wavenumber range when the large scale flow on the centerline of the mixing layer is self-preserving. The data are also consistent with the existence of universal inertial subranges for the spectra of each interaction mode.

Contaminant source identification using semi-supervised machine learning

NASA Astrophysics Data System (ADS)

Vesselinov, Velimir V.; Alexandrov, Boian S.; O'Malley, Daniel

2018-05-01

Identification of the original groundwater types present in geochemical mixtures observed in an aquifer is a challenging but very important task. Frequently, some of the groundwater types are related to different infiltration and/or contamination sources associated with various geochemical signatures and origins. The characterization of groundwater mixing processes typically requires solving complex inverse models representing groundwater flow and geochemical transport in the aquifer, where the inverse analysis accounts for available site data. Usually, the model is calibrated against the available data characterizing the spatial and temporal distribution of the observed geochemical types. Numerous different geochemical constituents and processes may need to be simulated in these models which further complicates the analyses. In this paper, we propose a new contaminant source identification approach that performs decomposition of the observation mixtures based on Non-negative Matrix Factorization (NMF) method for Blind Source Separation (BSS), coupled with a custom semi-supervised clustering algorithm. Our methodology, called NMFk, is capable of identifying (a) the unknown number of groundwater types and (b) the original geochemical concentration of the contaminant sources from measured geochemical mixtures with unknown mixing ratios without any additional site information. NMFk is tested on synthetic and real-world site data. The NMFk algorithm works with geochemical data represented in the form of concentrations, ratios (of two constituents; for example, isotope ratios), and delta notations (standard normalized stable isotope ratios).

Contaminant source identification using semi-supervised machine learning

DOE PAGES

Vesselinov, Velimir Valentinov; Alexandrov, Boian S.; O’Malley, Dan

2017-11-08

Identification of the original groundwater types present in geochemical mixtures observed in an aquifer is a challenging but very important task. Frequently, some of the groundwater types are related to different infiltration and/or contamination sources associated with various geochemical signatures and origins. The characterization of groundwater mixing processes typically requires solving complex inverse models representing groundwater flow and geochemical transport in the aquifer, where the inverse analysis accounts for available site data. Usually, the model is calibrated against the available data characterizing the spatial and temporal distribution of the observed geochemical types. Numerous different geochemical constituents and processes may needmore » to be simulated in these models which further complicates the analyses. In this paper, we propose a new contaminant source identification approach that performs decomposition of the observation mixtures based on Non-negative Matrix Factorization (NMF) method for Blind Source Separation (BSS), coupled with a custom semi-supervised clustering algorithm. Our methodology, called NMFk, is capable of identifying (a) the unknown number of groundwater types and (b) the original geochemical concentration of the contaminant sources from measured geochemical mixtures with unknown mixing ratios without any additional site information. NMFk is tested on synthetic and real-world site data. Finally, the NMFk algorithm works with geochemical data represented in the form of concentrations, ratios (of two constituents; for example, isotope ratios), and delta notations (standard normalized stable isotope ratios).« less

Contaminant source identification using semi-supervised machine learning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vesselinov, Velimir Valentinov; Alexandrov, Boian S.; O’Malley, Dan

Identification of the original groundwater types present in geochemical mixtures observed in an aquifer is a challenging but very important task. Frequently, some of the groundwater types are related to different infiltration and/or contamination sources associated with various geochemical signatures and origins. The characterization of groundwater mixing processes typically requires solving complex inverse models representing groundwater flow and geochemical transport in the aquifer, where the inverse analysis accounts for available site data. Usually, the model is calibrated against the available data characterizing the spatial and temporal distribution of the observed geochemical types. Numerous different geochemical constituents and processes may needmore » to be simulated in these models which further complicates the analyses. In this paper, we propose a new contaminant source identification approach that performs decomposition of the observation mixtures based on Non-negative Matrix Factorization (NMF) method for Blind Source Separation (BSS), coupled with a custom semi-supervised clustering algorithm. Our methodology, called NMFk, is capable of identifying (a) the unknown number of groundwater types and (b) the original geochemical concentration of the contaminant sources from measured geochemical mixtures with unknown mixing ratios without any additional site information. NMFk is tested on synthetic and real-world site data. Finally, the NMFk algorithm works with geochemical data represented in the form of concentrations, ratios (of two constituents; for example, isotope ratios), and delta notations (standard normalized stable isotope ratios).« less

Using mixed methods effectively in prevention science: designs, procedures, and examples.

PubMed

Zhang, Wanqing; Watanabe-Galloway, Shinobu

2014-10-01

There is growing interest in using a combination of quantitative and qualitative methods to generate evidence about the effectiveness of health prevention, services, and intervention programs. With the emerging importance of mixed methods research across the social and health sciences, there has been an increased recognition of the value of using mixed methods for addressing research questions in different disciplines. We illustrate the mixed methods approach in prevention research, showing design procedures used in several published research articles. In this paper, we focused on two commonly used mixed methods designs: concurrent and sequential mixed methods designs. We discuss the types of mixed methods designs, the reasons for, and advantages of using a particular type of design, and the procedures of qualitative and quantitative data collection and integration. The studies reviewed in this paper show that the essence of qualitative research is to explore complex dynamic phenomena in prevention science, and the advantage of using mixed methods is that quantitative data can yield generalizable results and qualitative data can provide extensive insights. However, the emphasis of methodological rigor in a mixed methods application also requires considerable expertise in both qualitative and quantitative methods. Besides the necessary skills and effective interdisciplinary collaboration, this combined approach also requires an open-mindedness and reflection from the involved researchers.

Prevalence and genetic diversity of rotavirus infection in children with acute gastroenteritis in a hospital setting, Nairobi Kenya in post vaccination era: a cross-sectional study

PubMed Central

Agutu, Mary-Theresa; Ongus, Julliette; Kombich, Janeth; Kamenwa, Rose; Nyangao, James; Kagira, John; Ogutu, Adelaide Ayoyi; Bitek, Austine

2017-01-01

Introduction Rotavirus is the leading cause of severe diarrhoea among infants and young children. Each year more than 611 000 children die from rotavirus gastroenteritis, and two million are hospitalized, worldwide. In Kenya, the impact of recent rotavirus vaccinations on morbidities has not been estimated. The study aimed at determining the prevalence and identity of rotavirus strains isolated from rotavirus-associated diarrhoea in vaccinated children presenting with acute gastroenteritis. Methods Two hundred and ninety eight specimen from children presented at Gertrude Childrens’ Hospital from January to June 2012 were tested by EIA (Enzyme-linked Immunosorbent Assay) for rotavirus antigens. Molecular characterization was conducted on rotavirus-positive specimens. Extracted viral RNA was separated by polyacrylamide gel electrophoresis (PAGE) and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. Results The prevalence rate of rotavirus was 31.5% (94/298). Of the rotavirus dsRNA, 57 (60.1%) gave visible RNA profiles, 38 (40.4%) assigned long electropherotypes while 19 (20.2%) were short electropherotypes. The strains among the vaccinated were G3P [4], G12P [6], G3P [6], G9P [4], G mixed G9/3P [4] and G1/3P [4]. Specifically, the G genotypes were G9/3 (5.3%), G9 (4.3%), G3 (4.3%), G12 (2.1%) and mixed G1/3 (1.1%). The P genotypes detected were P [4] (5.3%) and P [6] (5.3%). Conclusion The present study demonstrates diversity in circulating genotypes with emergence of genotypes G3, G9, G12 and mixed genotypes G9/3 and recommends that vaccines should be formulated with a broad range of strains to include G9 and G12. PMID:28451016

Prevalence and genetic diversity of rotavirus infection in children with acute gastroenteritis in a hospital setting, Nairobi Kenya in post vaccination era: a cross-sectional study.

PubMed

Agutu, Mary-Theresa; Ongus, Julliette; Kombich, Janeth; Kamenwa, Rose; Nyangao, James; Kagira, John; Ogutu, Adelaide Ayoyi; Bitek, Austine

2017-01-01

Rotavirus is the leading cause of severe diarrhoea among infants and young children. Each year more than 611 000 children die from rotavirus gastroenteritis, and two million are hospitalized, worldwide. In Kenya, the impact of recent rotavirus vaccinations on morbidities has not been estimated. The study aimed at determining the prevalence and identity of rotavirus strains isolated from rotavirus-associated diarrhoea in vaccinated children presenting with acute gastroenteritis. Two hundred and ninety eight specimen from children presented at Gertrude Childrens' Hospital from January to June 2012 were tested by EIA (Enzyme-linked Immunosorbent Assay) for rotavirus antigens. Molecular characterization was conducted on rotavirus-positive specimens. Extracted viral RNA was separated by polyacrylamide gel electrophoresis (PAGE) and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. The prevalence rate of rotavirus was 31.5% (94/298). Of the rotavirus dsRNA, 57 (60.1%) gave visible RNA profiles, 38 (40.4%) assigned long electropherotypes while 19 (20.2%) were short electropherotypes. The strains among the vaccinated were G3P [4], G12P [6], G3P [6], G9P [4], G mixed G9/3P [4] and G1/3P [4]. Specifically, the G genotypes were G9/3 (5.3%), G9 (4.3%), G3 (4.3%), G12 (2.1%) and mixed G1/3 (1.1%). The P genotypes detected were P [4] (5.3%) and P [6] (5.3%). The present study demonstrates diversity in circulating genotypes with emergence of genotypes G3, G9, G12 and mixed genotypes G9/3 and recommends that vaccines should be formulated with a broad range of strains to include G9 and G12.

Analytical study of mixed electroosmotic-pressure-driven flow in rectangular micro-channels

NASA Astrophysics Data System (ADS)

Movahed, Saeid; Kamali, Reza; Eghtesad, Mohammad; Khosravifard, Amir

2013-09-01

Operational state of many miniaturized devices deals with flow field in microchannels. Pressure-driven flow (PDF) and electroosmotic flow (EOF) can be recognized as the two most important types of the flow field in such channels. EOF has many advantages in comparison with PDF, such as being vibration free and not requiring any external mechanical pumps or moving parts. However, the disadvantages of this type of flow such as Joule heating, electrophoresis demixing, and not being suitable for mobile devices must be taken into consideration carefully. By using mixed electroosmotic/pressure-driven flow, the role of EOF in producing desired velocity profile will be reduced. In this way, the advantages of EOF can be exploited, and its disadvantages can be prevented. Induced pressure gradient can be utilized in order to control the separation in the system. Furthermore, in many complicated geometries such as T-shape microchannels, turns may induce pressure gradient to the electroosmotic velocity. While analytical formulas are completely essential for analysis and control of any industrial and laboratory microdevices, lack of such formulas in the literature for solving Poisson-Boltzmann equation and predicting electroosmotic velocity field in rectangular domains is evident. In the present study, first a novel method is proposed to solve Poisson-Boltzmann equation (PBE). Subsequently, this solution is utilized to find the electroosmotic and the mixed electroosmotic/pressure-driven velocity profile in a rectangular domain of the microchannels. To demonstrate the accuracy of the presented analytical method in solving PBE and finding electroosmotic velocity, a general nondimensional example is analyzed, and the results are compared with the solution of boundary element method. Additionally, the effects of different nondimensional parameters and also aspect ratio of channels on the electroosmotic part of the flow field will be investigated.

Urinary incontinence after vaginal delivery or cesarean section.

PubMed

Borges, João Bosco Ramos; Guarisi, Telma; Camargo, Ana Carolina Marchesini de; Gollop, Thomaz Rafael; Machado, Rogério Bonassi; Borges, Pítia Cárita de Godoy

2010-06-01

To assess the prevalence of stress urinary incontinence, urge incontinence and mixed urinary incontinence among women residing in the city of Jundiaí (São Paulo, Brazil), and the relation between the type of incontinence and the obstetric history of these women. A cross-sectional community-based study was conducted. A total of 332 women were interviewed; they were seen for whatever reason at the public primary healthcare units of the city of Jundiaí, from March 2005 to April 2006. A pre-tested questionnaire was administered and consisted of questions used in the EPINCONT Study (Epidemiology of Incontinence in the County of Nord-Trondelag). Statistical analysis was carried out using the χ2 test and odds ratio (95%CI). Urinary incontinence was a complaint for 23.5% of the women interviewed. Stress urinary incontinence prevailed (50%), followed by mixed urinary incontinence (35%) and urge incontinence (15%). Being in the age group of 35-64 years, having a body mass index of 30 or greater and having had only vaginal delivery or cesarean section, with uterine contraction, regardless of the number of pregnancies, were factors associated with stress urinary incontinence. However, being in the age group of 55 or older, having a body mass index of 30 or greater and having had three or more pregnancies, only with vaginal deliveries, were factors associated with mixed urinary incontinence. One third of the interviewees complained of some type of urinary incontinence, and half of them presented stress urinary incontinence. Cesarean section, only when not preceded by contractions, was not associated with stress urinary incontinence. The body mass index is only relevant when the stress factor is present.

Methodological reporting in qualitative, quantitative, and mixed methods health services research articles.

PubMed

Wisdom, Jennifer P; Cavaleri, Mary A; Onwuegbuzie, Anthony J; Green, Carla A

2012-04-01

Methodologically sound mixed methods research can improve our understanding of health services by providing a more comprehensive picture of health services than either method can alone. This study describes the frequency of mixed methods in published health services research and compares the presence of methodological components indicative of rigorous approaches across mixed methods, qualitative, and quantitative articles. All empirical articles (n = 1,651) published between 2003 and 2007 from four top-ranked health services journals. All mixed methods articles (n = 47) and random samples of qualitative and quantitative articles were evaluated to identify reporting of key components indicating rigor for each method, based on accepted standards for evaluating the quality of research reports (e.g., use of p-values in quantitative reports, description of context in qualitative reports, and integration in mixed method reports). We used chi-square tests to evaluate differences between article types for each component. Mixed methods articles comprised 2.85 percent (n = 47) of empirical articles, quantitative articles 90.98 percent (n = 1,502), and qualitative articles 6.18 percent (n = 102). There was a statistically significant difference (χ(2) (1) = 12.20, p = .0005, Cramer's V = 0.09, odds ratio = 1.49 [95% confidence interval = 1,27, 1.74]) in the proportion of quantitative methodological components present in mixed methods compared to quantitative papers (21.94 versus 47.07 percent, respectively) but no statistically significant difference (χ(2) (1) = 0.02, p = .89, Cramer's V = 0.01) in the proportion of qualitative methodological components in mixed methods compared to qualitative papers (21.34 versus 25.47 percent, respectively). Few published health services research articles use mixed methods. The frequency of key methodological components is variable. Suggestions are provided to increase the transparency of mixed methods studies and the presence of key methodological components in published reports. © Health Research and Educational Trust.

Methodological Reporting in Qualitative, Quantitative, and Mixed Methods Health Services Research Articles

PubMed Central

Wisdom, Jennifer P; Cavaleri, Mary A; Onwuegbuzie, Anthony J; Green, Carla A

2012-01-01

Objectives Methodologically sound mixed methods research can improve our understanding of health services by providing a more comprehensive picture of health services than either method can alone. This study describes the frequency of mixed methods in published health services research and compares the presence of methodological components indicative of rigorous approaches across mixed methods, qualitative, and quantitative articles. Data Sources All empirical articles (n = 1,651) published between 2003 and 2007 from four top-ranked health services journals. Study Design All mixed methods articles (n = 47) and random samples of qualitative and quantitative articles were evaluated to identify reporting of key components indicating rigor for each method, based on accepted standards for evaluating the quality of research reports (e.g., use of p-values in quantitative reports, description of context in qualitative reports, and integration in mixed method reports). We used chi-square tests to evaluate differences between article types for each component. Principal Findings Mixed methods articles comprised 2.85 percent (n = 47) of empirical articles, quantitative articles 90.98 percent (n = 1,502), and qualitative articles 6.18 percent (n = 102). There was a statistically significant difference (χ2(1) = 12.20, p = .0005, Cramer's V = 0.09, odds ratio = 1.49 [95% confidence interval = 1,27, 1.74]) in the proportion of quantitative methodological components present in mixed methods compared to quantitative papers (21.94 versus 47.07 percent, respectively) but no statistically significant difference (χ2(1) = 0.02, p = .89, Cramer's V = 0.01) in the proportion of qualitative methodological components in mixed methods compared to qualitative papers (21.34 versus 25.47 percent, respectively). Conclusion Few published health services research articles use mixed methods. The frequency of key methodological components is variable. Suggestions are provided to increase the transparency of mixed methods studies and the presence of key methodological components in published reports. PMID:22092040

A scoring system for appraising mixed methods research, and concomitantly appraising qualitative, quantitative and mixed methods primary studies in Mixed Studies Reviews.

PubMed

Pluye, Pierre; Gagnon, Marie-Pierre; Griffiths, Frances; Johnson-Lafleur, Janique

2009-04-01

A new form of literature review has emerged, Mixed Studies Review (MSR). These reviews include qualitative, quantitative and mixed methods studies. In the present paper, we examine MSRs in health sciences, and provide guidance on processes that should be included and reported. However, there are no valid and usable criteria for concomitantly appraising the methodological quality of the qualitative, quantitative and mixed methods studies. To propose criteria for concomitantly appraising the methodological quality of qualitative, quantitative and mixed methods studies or study components. A three-step critical review was conducted. 2322 references were identified in MEDLINE, and their titles and abstracts were screened; 149 potentially relevant references were selected and the full-text papers were examined; 59 MSRs were retained and scrutinized using a deductive-inductive qualitative thematic data analysis. This revealed three types of MSR: convenience, reproducible, and systematic. Guided by a proposal, we conducted a qualitative thematic data analysis of the quality appraisal procedures used in the 17 systematic MSRs (SMSRs). Of 17 SMSRs, 12 showed clear quality appraisal procedures with explicit criteria but no SMSR used valid checklists to concomitantly appraise qualitative, quantitative and mixed methods studies. In two SMSRs, criteria were developed following a specific procedure. Checklists usually contained more criteria than needed. In four SMSRs, a reliability assessment was described or mentioned. While criteria for quality appraisal were usually based on descriptors that require specific methodological expertise (e.g., appropriateness), no SMSR described the fit between reviewers' expertise and appraised studies. Quality appraisal usually resulted in studies being ranked by methodological quality. A scoring system is proposed for concomitantly appraising the methodological quality of qualitative, quantitative and mixed methods studies for SMSRs. This scoring system may also be used to appraise the methodological quality of qualitative, quantitative and mixed methods components of mixed methods research.

Characterisation of seasonal flood types according to timescales in mixed probability distributions

NASA Astrophysics Data System (ADS)

Fischer, Svenja; Schumann, Andreas; Schulte, Markus

2016-08-01

When flood statistics are based on annual maximum series (AMS), the sample often contains flood peaks, which differ in their genesis. If the ratios among event types change over the range of observations, the extrapolation of a probability distribution function (pdf) can be dominated by a majority of events that belong to a certain flood type. If this type is not typical for extraordinarily large extremes, such an extrapolation of the pdf is misleading. To avoid this breach of the assumption of homogeneity, seasonal models were developed that differ between winter and summer floods. We show that a distinction between summer and winter floods is not always sufficient if seasonal series include events with different geneses. Here, we differentiate floods by their timescales into groups of long and short events. A statistical method for such a distinction of events is presented. To demonstrate their applicability, timescales for winter and summer floods in a German river basin were estimated. It is shown that summer floods can be separated into two main groups, but in our study region, the sample of winter floods consists of at least three different flood types. The pdfs of the two groups of summer floods are combined via a new mixing model. This model considers that information about parallel events that uses their maximum values only is incomplete because some of the realisations are overlaid. A statistical method resulting in an amendment of statistical parameters is proposed. The application in a German case study demonstrates the advantages of the new model, with specific emphasis on flood types.

Nuclear chromatin-concentrated osteoblasts in renal bone diseases.

PubMed

Kazama, Junichiro James; Yamamoto, Suguru; Narita, Ichiei; Kurihara, Satoshi

2011-06-01

The morphological appearance of an osteoblast largely alters with its differentiation and maturation, along with the change of cell function. We quantitatively observed the osteoblast morphology and compared it with bone metabolism. Biopsied iliac bone samples obtained from 77 dialysis patients (14 mild change, 37 osteitis fibrosa, 2 osteomalacia, 8 mixed, and 16 adynamic bone) were included in the study. Osteoblast appearances were classified into three groups: (i) type II and III osteoblasts, namely, active osteoblasts characterized by cuboidal or columnar shapes with or without a nuclear clear zone; (ii) type IV osteoblasts, lining osteoblasts characterized by extremely thin cytoplasm; and (iii) type V osteoblasts, apoptotic osteoblasts characterized by nuclear chromatin concentration. The results were quantitatively expressed as the length of bone surface covered by each type of osteoblasts. The type II and III osteoblasts were predominant in osteitis fibrosa, mixed, and mild change. The type IV osteoblasts were overwhelmingly predominant in adynamic bone. The type V osteoblasts appeared most frequently in osteitis fibrosa, followed by mixed and mild change. Both absolute and relative lengths of bone surface covered by the type V osteoblasts were significantly higher in the high-turnover bone group (osteitis fibrosa and mixed) than the low-turnover bone group (adynamic bone and osteomalacia). The type V osteoblasts were slightly correlated with serum intact parathyroid hormone levels. In conclusion, a high bone-turnover condition seems to be associated with the promotion of osteoblastic apoptosis in dialysis patients. This finding may explain the fact that osteopenia develops faster in CKD patients with high turnover of bone. © 2011 The Authors. Therapeutic Apheresis and Dialysis © 2011 International Society for Apheresis.

Effect of zeta potential on the performance of a ring-type electroosmotic mixer.

PubMed

Kim, T A; Koo, K H; Kim, Y J

2009-12-01

In order to achieve faster mixing, a new type of electrokinetic mixer with a T-type channel is introduced. The proposed mixer takes two fluids from different inlets and combines them into a single channel. The fluids then enter a mixing chamber with different inner and outer radii. Four microelectrodes are positioned on the outer wall of the mixing chamber. The electric potentials on the four microelectrodes are sinusoidal with respect to time and have various maximum voltages, zeta potentials and frequency values. The working fluid is water and each inlet has a different initial concentration values. The incompressible Navier-Stokes equation is solved in the channel, with a slip boundary condition on the inner and outer walls of the mixing chamber. The convection-diffusion equation is used to describe the concentration of the dissolved substances in the fluid. The pressure, concentration and flow fields in the channel are calculated and the results are graphically depicted for various flow and electric conditions.

7 CFR 29.3040 - Mixed color (M).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Mixed color (M). 29.3040 Section 29.3040 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Mixed color (M). Distinctly different colors of the type mingled together. (See Rule 16.) [24 FR 8771...

7 CFR 29.3040 - Mixed color (M).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed color (M). 29.3040 Section 29.3040 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Mixed color (M). Distinctly different colors of the type mingled together. (See Rule 16.) [24 FR 8771...

7 CFR 29.3040 - Mixed color (M).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed color (M). 29.3040 Section 29.3040 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Mixed color (M). Distinctly different colors of the type mingled together. (See Rule 16.) [24 FR 8771...

7 CFR 29.3040 - Mixed color (M).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed color (M). 29.3040 Section 29.3040 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Mixed color (M). Distinctly different colors of the type mingled together. (See Rule 16.) [24 FR 8771...

7 CFR 29.3040 - Mixed color (M).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed color (M). 29.3040 Section 29.3040 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Mixed color (M). Distinctly different colors of the type mingled together. (See Rule 16.) [24 FR 8771...

A climatology of weather-driven mixing events in a dimictic Arctic lake

NASA Astrophysics Data System (ADS)

Cooke, Melanie; MacIntyre, Sally; Kushner, Paul

2014-05-01

For dimictic and polymictic Arctic lakes, mixing during the ice-free season is primarily controlled by the passage of cold fronts and their associated strong winds. At Toolik Lake, a Long Term Ecological Research site in Alaska, year-to-year variability in lake stability and mixing frequency has been considerable over the past 14 summers. Mixing is important for lake productivity, distributing dissolved gases and nutrients through the water column. Summertime Arctic warming might be expected to stabilize Arctic lakes such as Toolik, but the control of individual weather events on a season's mixing characteristics complicates the ability to predict trends in stability and mixing. With this motivation, this work aims to characterize weather systems that are conducive to mixing at Toolik. High resolution lake and meteorological data from the site were used to characterize mixing while atmospheric reanalysis data were used to describe the weather systems. Mixing events were first identified using an automated algorithm based on Lake Number and lake thermal structure. The algorithm identified mixing events that are separated by at least the timescale of weather systems, so that any given weather event should cause at most one mixing event. Because low Lake Number conditions typically highlight strong wind events, temperature profile data over time were used to identify thermocline deepening as a complementary indicator for mixing. Mixing events were found to be most often characterized by simultaneous occurrence of a low Lake Number condition and thermocline deepening. Once mixing events were identified, they were classified according to their corresponding atmospheric structures. Two primary weather system types with distinct characteristics were determined to be associated with mixing. The analysis suggests that changing the occurrence of these weather system types might change the summertime thermal structure of Toolik Lake, and by extension other lakes in the region.

A Comparison of Two Chord Keyboard Coding Systems for Alphanumeric Data Entry.

DTIC Science & Technology

1987-06-01

These rates were achieved while typing new material with no more than two errors per minute. No IBM machine has yet been marketed using this chord...type", subject’s typing rates on the standard typewriter ranged from 54.5 CPM to 176.5 CPM for mixed alphanumeric data. Nine of the ten subjects...dot Keyboard and the Standard Keyboard Material Keyboard Entry Rate All Letters Alpha-dot Keyboard 65.25 CPM Mixed Alpha/Numeric Text Alpha-dot

Completed Beltrami-Michell formulation for analyzing mixed boundary value problems in elasticity

NASA Technical Reports Server (NTRS)

Patnaik, Surya N.; Kaljevic, Igor; Hopkins, Dale A.; Saigal, Sunil

1995-01-01

In elasticity, the method of forces, wherein stress parameters are considered as the primary unknowns, is known as the Beltrami-Michell formulation (BMF). The existing BMF can only solve stress boundary value problems; it cannot handle the more prevalent displacement of mixed boundary value problems of elasticity. Therefore, this formulation, which has restricted application, could not become a true alternative to the Navier's displacement method, which can solve all three types of boundary value problems. The restrictions in the BMF have been alleviated by augmenting the classical formulation with a novel set of conditions identified as the boundary compatibility conditions. This new method, which completes the classical force formulation, has been termed the completed Beltrami-Michell formulation (CBMF). The CBMF can solve general elasticity problems with stress, displacement, and mixed boundary conditions in terms of stresses as the primary unknowns. The CBMF is derived from the stationary condition of the variational functional of the integrated force method. In the CBMF, stresses for kinematically stable structures can be obtained without any reference to the displacements either in the field or on the boundary. This paper presents the CBMF and its derivation from the variational functional of the integrated force method. Several examples are presented to demonstrate the applicability of the completed formulation for analyzing mixed boundary value problems under thermomechanical loads. Selected example problems include a cylindrical shell wherein membrane and bending responses are coupled, and a composite circular plate.

Identification of hydrometeor mixtures in polarimetric radar measurements and their linear de-mixing

NASA Astrophysics Data System (ADS)

Besic, Nikola; Ventura, Jordi Figueras i.; Grazioli, Jacopo; Gabella, Marco; Germann, Urs; Berne, Alexis

2017-04-01

The issue of hydrometeor mixtures affects radar sampling volumes without a clear dominant hydrometeor type. Containing a number of different hydrometeor types which significantly contribute to the polarimetric variables, these volumes are likely to occur in the vicinity of the melting layer and mainly, at large distance from a given radar. Motivated by potential benefits for both quantitative and qualitative applications of dual-pol radar, we propose a method for the identification of hydrometeor mixtures and their subsequent linear de-mixing. This method is intrinsically related to our recently proposed semi-supervised approach for hydrometeor classification. The mentioned classification approach [1] performs labeling of radar sampling volumes by using as a criterion the Euclidean distance with respect to five-dimensional centroids, depicting nine hydrometeor classes. The positions of the centroids in the space formed by four radar moments and one external parameter (phase indicator), are derived through a technique of k-medoids clustering, applied on a selected representative set of radar observations, and coupled with statistical testing which introduces the assumed microphysical properties of the different hydrometeor types. Aside from a hydrometeor type label, each radar sampling volume is characterized by an entropy estimate, indicating the uncertainty of the classification. Here, we revisit the concept of entropy presented in [1], in order to emphasize its presumed potential for the identification of hydrometeor mixtures. The calculation of entropy is based on the estimate of the probability (pi ) that the observation corresponds to the hydrometeor type i (i = 1,ṡṡṡ9) . The probability is derived from the Euclidean distance (di ) of the observation to the centroid characterizing the hydrometeor type i . The parametrization of the d → p transform is conducted in a controlled environment, using synthetic polarimetric radar datasets. It ensures balanced entropy values: low for pure volumes, and high for different possible combinations of mixed hydrometeors. The parametrized entropy is further on applied to real polarimetric C and X band radar datasets, where we demonstrate the potential of linear de-mixing using a simplex formed by a set of pre-defined centroids in the five-dimensional space. As main outcome, the proposed approach allows to provide plausible proportions of the different hydrometeors contained in a given radar sampling volume. [1] Besic, N., Figueras i Ventura, J., Grazioli, J., Gabella, M., Germann, U., and Berne, A.: Hydrometeor classification through statistical clustering of polarimetric radar measurements: a semi-supervised approach, Atmos. Meas. Tech., 9, 4425-4445, doi:10.5194/amt-9-4425-2016, 2016.

S-type granitic magmas—petrogenetic issues, models and evidence

NASA Astrophysics Data System (ADS)

Clemens, J. D.

2003-04-01

Despite a perception that it represents a perverse divergence, it is perfectly possible to believe in the existence of S- and I-type granites (and the implications for the nature of their protoliths), and to disbelieve in the applicability of the restite-unmixing model for chemical variation in granitic magmas. White and Chappell erected the S-I classification with impeccable validity. The isotopic evidence demands contrasting source reservoirs for S- and I-type granitic magmas. However, the major advance was not the classification, but the recognition that highly contrasting parental materials must be involved in the genesis of granitic magmas. The restite-unmixing model is commonly seen as a companion to the S-I classification, but it is really a separate issue. This model implies that the compositions of granites 'image' those of their source rocks in a simple way. However, there are other equally valid models that can explain the data, and none of them represents a unique solution. The most cogent explanation for the high-grade metasedimentary enclaves in most S-type granites is that they represent mid-crustal xenoliths; restitic enclaves are either rare or absent. Inherited zircons in S-type rocks are certainly restitic. However, the occurrence of a substantial restitic zircon population does not imply an equally substantial restitic component in the rest of the rock. Zircon and zirconium behaviours are controlled by disequilibrium and kinetics, and Zr contents of granitic rocks can rarely be used to infer magma temperatures. Since the dominant ages among inherited zircons in Lachlan Fold Belt (LFB) S-type granites are Ordovician and Proterozoic, it seems likely that crust of this age, but geochemically different from the exposed rocks, not only underlies much of the LFB but also forms a component in the granite magma sources. The evidence is overwhelming that the dark, microgranular enclaves that occur in both S- and I-type granites are igneous in origin. They represent globules of quenched, more mafic magma mingled and modified by exchange with the host granitic magma. However, magma mixing does not appear to be a significant process affecting the chemical evolution of the host magmas. Likewise, the multicomponent mixing models erected for some granitic rock suites are mathematically nonunique and, in some cases, violate constraints from isotopic studies. S- and I-type magmas commonly retain their distinct identities. This suggests limited source mixing, limited magma mixing and limited wall-rock assimilation. Though intermediate types certainly exist, they are probably relatively minor in volume. Crystal fractionation probably plays the major role in the differentiation of very many granitic magmas, including most S-types, especially those emplaced at high crustal levels or in the volcanic environment. Minor mechanisms include magma mixing, wall-rock assimilation and restite unmixing. Isotopic variations within plutons and in granite suites could be caused by source heterogeneities, magma mixing, assimilation and even by isotopic disequilibrium. However, source heterogeneity, coupled with the inefficiency of magma mixing is probably the major cause of observed heterogeneity. Normal geothermal gradients are seldom sufficient to provide the necessary heat for partial melting of the crust, and crustal thickening likewise fails to provide sufficient heat. Generally, the mantle must be the major heat source. This might be provided through mantle upwelling and crustal thinning, and possibly through the intra- and underplating of mafic magmas. Upper crustal extension seems to have been common in regions undergoing granitic magmatism. Migmatites probably provide poor analogues of granite source regions because they are mostly formed by fluid-present reactions. Granitic magmas are mostly formed by fluid-absent processes. Where we do see rare evidence for arrested fluid-absent partial melting, the melt fraction is invariably concentrated into small shear zones, veinlets and small dykes. Thus, it seems likely that dyking is important in transporting granitic magma on a variety of scales and at many crustal levels. However, one major missing link in the chain is the mechanism by which melt fractions, in small-scale segregations occurring over a wide area, can be gathered and focused to efficiently feed much wider-spaced major magma conduits. Answers may lie in the geometry of the melting zones and in the tendency of younger propagating fractures to curve toward and merge with older ones. Self-organization almost certainly plays a role.

Biophysical controls on soil respiration in the dominant patch types of an old-growth, mixed-conifer forest

Treesearch

Siyan Ma; Jiquan Chen; John R. Butnor; Malcolm North; Eugénie S. Euskirchen; Brian Oakley

2005-01-01

Little is known about biophysical controls on soil respiration in California's Sierra Nevada old-growth, mixed-conifer forests. Using portable and automated soil respiration sampling units, we measured soil respiration rate (SRR) in three dominant patch types: closed canopy (CC), ceanothus-dominated patches (CECO), and open canopy (OC). SRR varied significantly...

On Visualizing Mixed-Type Data: A Joint Metric Approach to Profile Construction and Outlier Detection

ERIC Educational Resources Information Center

Grané, Aurea; Romera, Rosario

2018-01-01

Survey data are usually of mixed type (quantitative, multistate categorical, and/or binary variables). Multidimensional scaling (MDS) is one of the most extended methodologies to visualize the profile structure of the data. Since the past 60s, MDS methods have been introduced in the literature, initially in publications in the psychometrics area.…

The Equivalence between (AB)[dagger] = B[dagger]A[dagger] and Other Mixed-Type Reverse-Order Laws

ERIC Educational Resources Information Center

Tian, Yongge

2006-01-01

The standard reverse-order law for the Moore-Penrose inverse of a matrix product is (AB)[dagger] = B[dagger]A[dagger]. The purpose of this article is to give a set of equivalences of this reverse-order law and other mixed-type reverse-order laws for the Moore-Penrose inverse of matrix products.

Seamless transitions from early prototypes to mature operational software - A technology that enables the process for planning and scheduling applications

NASA Technical Reports Server (NTRS)

Hornstein, Rhoda S.; Wunderlich, Dana A.; Willoughby, John K.

1992-01-01

New and innovative software technology is presented that provides a cost effective bridge for smoothly transitioning prototype software, in the field of planning and scheduling, into an operational environment. Specifically, this technology mixes the flexibility and human design efficiency of dynamic data typing with the rigor and run-time efficiencies of static data typing. This new technology provides a very valuable tool for conducting the extensive, up-front system prototyping that leads to specifying the correct system and producing a reliable, efficient version that will be operationally effective and will be accepted by the intended users.

Single-photon superradiant beating from a Doppler-broadened ladder-type atomic ensemble

NASA Astrophysics Data System (ADS)

Lee, Yoon-Seok; Lee, Sang Min; Kim, Heonoh; Moon, Han Seb

2017-12-01

We report on heralded-single-photon superradiant beating in the spontaneous four-wave mixing process of Doppler-broadened ladder-type 87Rb atoms. When Doppler-broadened atoms contribute to two-photon coherence, the detection probability amplitudes of the heralded single photons are coherently superposed despite inhomogeneous broadened atomic media. Single-photon superradiant beating is observed, which constitutes evidence for the coherent superposition of two-photon amplitudes from different velocity classes in the Doppler-broadened atomic ensemble. We present a theoretical model in which the single-photon superradiant beating originates from the interference between wavelength-separated two-photon amplitudes via the reabsorption filtering effect.

A cytogenetic analysis of 2 cases of phosphaturic mesenchymal tumor of mixed connective tissue type.

PubMed

Graham, Rondell P; Hodge, Jennelle C; Folpe, Andrew L; Oliveira, Andre M; Meyer, Kevin J; Jenkins, Robert B; Sim, Franklin H; Sukov, William R

2012-08-01

Phosphaturic mesenchymal tumor of mixed connective tissue type is a rare, histologically distinctive mesenchymal neoplasm associated with tumor-induced osteomalacia resulting from production of the phosphaturic hormone fibroblast growth factor 23. Because of its rarity, specific genetic alterations that contribute to the pathogenesis of these tumors have yet to be elucidated. Herein, we report the abnormal karyotypes from 2 cases of confirmed phosphaturic mesenchymal tumor of mixed connective tissue type. G-banded analysis demonstrated the first tumor to have a karyotype of 46,Y,t(X;3;14)(q13;p25;q21)[15]/46XY[5], and the second tumor to have a karyotype of 46, XY,add(2)(q31),add(4)(q31.1)[2]/92,slx2[3]/46,sl,der(2)t(2;4)(q14.2;p14),der(4)t(2;4)(q14.2;p14),add(4)(q31.1)[10]/46,sdl,add(13)(q34)[4]/92,sdl2x2[1]. These represent what is, to our knowledge, the first examples of abnormal karyotypes obtained from phosphaturic mesenchymal tumor of mixed connective tissue type. Copyright © 2012 Elsevier Inc. All rights reserved.

Immediate periodontal bone plate changes induced by rapid maxillary expansion in the early mixed dentition: CT findings

PubMed Central

Garib, Daniela Gamba; Menezes, Maria Helena Ocké; da Silva Filho, Omar Gabriel; dos Santos, Patricia Bittencourt Dutra

2014-01-01

Objective This study aimed at evaluating buccal and lingual bone plate changes caused by rapid maxillary expansion (RME) in the mixed dentition by means of computed tomography (CT). Methods The sample comprised spiral CT exams taken from 22 mixed dentition patients from 6 to 9 years of age (mean age of 8.1 years) presenting constricted maxillary arch treated with Haas-type expanders. Patients were submitted to spiral CT scan before expansion and after the screw activation period with a 30-day interval between T1 and T2. Multiplanar reconstruction was used to measure buccal and lingual bone plate thickness and buccal bone crest level of maxillary posterior deciduous and permanent teeth. Changes induced by expansion were evaluated using paired t test (p < 0.05). Results Thickness of buccal and lingual bone plates of posterior teeth remained unchanged during the expansion period, except for deciduous second molars which showed a slight reduction in bone thickness at the distal region of its buccal aspect. Buccal bone dehiscences were not observed in the supporting teeth after expansion. Conclusion RME performed in mixed dentition did not produce immediate undesirable effects on periodontal bone tissues. PMID:25162564

Quality Assessment of Mixed and Ceramic Recycled Aggregates from Construction and Demolition Wastes in the Concrete Manufacture According to the Spanish Standard †

PubMed Central

Rodríguez-Robles, Desirée; García-González, Julia; Juan-Valdés, Andrés; Pozo, Julia Mª Morán-del; Guerra-Romero, Manuel I

2014-01-01

Construction and demolition waste (CDW) constitutes an increasingly significant problem in society due to the volume generated, rendering sustainable management and disposal problematic. The aim of this study is to identify a possible reuse option in the concrete manufacturing for recycled aggregates with a significant ceramic content: mixed recycled aggregates (MixRA) and ceramic recycled aggregates (CerRA). In order to do so, several tests are conducted in accordance with the Spanish Code on Structural Concrete (EHE-08) to determine the composition in weight and physic-mechanical characteristics (particle size distributions, fine content, sand equivalent, density, water absorption, flakiness index, and resistance to fragmentation) of the samples for the partial inclusion of the recycled aggregates in concrete mixes. The results of these tests clearly support the hypothesis that this type of material may be suitable for such partial replacements if simple pretreatment is carried out. Furthermore, this measure of reuse is in line with European, national, and regional policies on sustainable development, and presents a solution to the environmental problem caused by the generation of CDW. PMID:28788164

Operational Planning for Multiple Heterogeneous Unmanned Aerial Vehicles in Three Dimensions

DTIC Science & Technology

2009-06-01

human input in the planning process. Two solution methods are presented: (1) a mixed-integer program, and (2) an algorithm that utilizes a metaheuristic ...and (2) an algorithm that utilizes a metaheuristic to generate composite variables for a linear program, called the Composite Operations Planning...that represent a path and an associated type of UAV. The reformulation is incorporated into an algorithm that uses a metaheuristic to generate the

[Infectious mononucleosis: etiology, immunological variants, methods of correction].

PubMed

Gordeets, A V; Savina, O G; Beniova, S N; Chernikova, A A

2011-01-01

Clinical options of infectious mononucleosis course depending on infecting agent etiology are presented for Epstein-Barr virus (EBV), cytomegalovirus (CMV), mono and mixed forms of the disease. Examined cytokine profiles demonstrate analogous changes of serum cytokines in the acute stage of the disease irrespective of etiological factors. Data show that it is important and useful clinically and immunologically to include immunomodulators--in particular, cycloferon--info a complex therapy of different types of mononucleosis.

Optical absorption and photoluminescence properties of Er3+ doped mixed alkali borate glasses.

PubMed

Ratnakaram, Y C; Kumar, A Vijaya; Naidu, D Tirupathi; Rao, J L

2005-07-01

An investigations of the optical absorption and fluorescence spectra of 0.2 mol% Er2O3 in mixed alkali borate glasses of the type 67.8B2O3 x xLi2O(32-x)Na2O, 67.8B2O3 x xLi2O(32-x)K2O and 67.8B2O3 x xNa2O(32-x)K2O (where x = 8, 12, 16, 20 and 24) are presented. The glasses were obtained by quenching melts consisting of H3BO3, Li2CO3, Na2CO3, K2CO3 and Er2O3 (950-1100 degrees C, 1.5-2 h) between two brass plates. Spectroscopic parameters like Racah (E1, E2 and E3), spin-orbit (xi(4f)) and configuration interaction (alpha) parameters are deduced as function of x. Using Judd-Ofelt theory, Judd-Ofelt intensity parameters (omega2, omega4 and omega6) are obtained. Radiative and non-radiative transition rates (A(T) and W(MPR)), radiative lifetimes (tauR), branching ratios (beta) and integrated absorption cross-sections (sigma) have been computed for certain excited states of Er3+ in these mixed alkali borate glasses. Emission spectra have been studied for all the three Er3+ doped mixed alkali borate glasses. The present paper throws light on the trends observed in the intensity parameters, radiative lifetimes, branching ratios and emission cross-sections as a function of x in these borate glasses, keeping in view the effect of mixed alkalies in borate glasses.

Points of Convergence in Music Education: The Use of Data Labels as a Strategy for Mixed Methods Integration

ERIC Educational Resources Information Center

Fitzpatrick, Kate R.

2016-01-01

Although the mixing of quantitative and qualitative data is an essential component of mixed methods research, the process of integrating both types of data in meaningful ways can be challenging. The purpose of this article is to describe the use of data labels in mixed methods research as a technique for the integration of qualitative and…

Mixed conditional logistic regression for habitat selection studies.

PubMed

Duchesne, Thierry; Fortin, Daniel; Courbin, Nicolas

2010-05-01

1. Resource selection functions (RSFs) are becoming a dominant tool in habitat selection studies. RSF coefficients can be estimated with unconditional (standard) and conditional logistic regressions. While the advantage of mixed-effects models is recognized for standard logistic regression, mixed conditional logistic regression remains largely overlooked in ecological studies. 2. We demonstrate the significance of mixed conditional logistic regression for habitat selection studies. First, we use spatially explicit models to illustrate how mixed-effects RSFs can be useful in the presence of inter-individual heterogeneity in selection and when the assumption of independence from irrelevant alternatives (IIA) is violated. The IIA hypothesis states that the strength of preference for habitat type A over habitat type B does not depend on the other habitat types also available. Secondly, we demonstrate the significance of mixed-effects models to evaluate habitat selection of free-ranging bison Bison bison. 3. When movement rules were homogeneous among individuals and the IIA assumption was respected, fixed-effects RSFs adequately described habitat selection by simulated animals. In situations violating the inter-individual homogeneity and IIA assumptions, however, RSFs were best estimated with mixed-effects regressions, and fixed-effects models could even provide faulty conclusions. 4. Mixed-effects models indicate that bison did not select farmlands, but exhibited strong inter-individual variations in their response to farmlands. Less than half of the bison preferred farmlands over forests. Conversely, the fixed-effect model simply suggested an overall selection for farmlands. 5. Conditional logistic regression is recognized as a powerful approach to evaluate habitat selection when resource availability changes. This regression is increasingly used in ecological studies, but almost exclusively in the context of fixed-effects models. Fitness maximization can imply differences in trade-offs among individuals, which can yield inter-individual differences in selection and lead to departure from IIA. These situations are best modelled with mixed-effects models. Mixed-effects conditional logistic regression should become a valuable tool for ecological research.

Mechanics of sucking: comparison between bottle feeding and breastfeeding

PubMed Central

2010-01-01

Background There is very little evidence of the similarity of the mechanics of maternal and bottle feeding. We assessed the mechanics of sucking in exclusive breastfeeding, exclusive bottle feeding, and mixed feeding. The hypothesis established was that physiological pattern for suckling movements differ depending on the type of feeding. According to this hypothesis, babies with breastfeeding have suckling movements at the breast that are different from the movements of suckling a teat of babies fed with bottle. Children with mixed feeding mix both types of suckling movements. Methods Cross-sectional study of infants aged 21-28 days with only maternal feeding or bottle feeding (234 mother-infant pairs), and a randomized open cross-over field trial in newborns aged 21-28 days and babies aged 3-5 months with mixed feeding (125 mother-infant pairs). Primary outcome measures were sucks and pauses. Results Infants aged 21-28 days exclusively bottle-fed showed fewer sucks and the same number of pauses but of longer duration compared to breastfeeding. In mixed feeding, bottle feeding compared to breastfeeding showed the same number of sucks but fewer and shorter pauses, both at 21-28 days and at 3-5 months. The mean number of breastfeedings in a day (in the mixed feed group) was 5.83 ± 1.93 at 21-28 days and 4.42 ± 1.67 at 3-5 months. In the equivalence analysis of the mixed feed group, the 95% confidence interval for bottle feeding/breastfeeding ratio laid outside the range of equivalence, indicating 5.9-8.7% fewer suction movements, and fewer pauses, and shorter duration of them in bottle feeding compared with breastfeeding. Conclusions The mechanics of sucking in mixed feeding lay outside the range of equivalence comparing bottle feeding with breastfeeding, although differences were small. Children with mixed feeding would mix both types of sucking movements (breastfeeding and bottle feeding) during the learning stage and adopt their own pattern. PMID:20149217

Modeling Photodetachment from HO2- Using the pd Case of the Generalized Mixed Character Molecular Orbital Model

NASA Astrophysics Data System (ADS)

Blackstone, Christopher C.; Sanov, Andrei

2016-06-01

Using the generalized model for photodetachment of electrons from mixed-character molecular orbitals, we gain insight into the nature of the HOMO of HO2- by treating it as a coherent superpostion of one p- and one d-type atomic orbital. Fitting the pd model function to the ab initio calculated HOMO of HO2- yields a fractional d-character, γp, of 0.979. The modeled curve of the anisotropy parameter, β, as a function of electron kinetic energy for a pd-type mixed character orbital is matched to the experimental data.

Advanced two-stage compressor program design of inlet stage

NASA Technical Reports Server (NTRS)

Bryce, C. A.; Paine, C. J.; Mccutcheon, A. R. S.; Tu, R. K.; Perrone, G. L.

1973-01-01

The aerodynamic design of an inlet stage for a two-stage, 10/1 pressure ratio, 2 lb/sec flow rate compressor is discussed. Initially a performance comparison was conducted for an axial, mixed flow and centrifugal second stage. A modified mixed flow configuration with tandem rotors and tandem stators was selected for the inlet stage. The term conical flow compressor was coined to describe a particular type of mixed flow compressor configuration which utilizes axial flow type blading and an increase in radius to increase the work input potential. Design details of the conical flow compressor are described.

78 FR 52099 - Onions Other Than Bermuda-Granex-Grano/Creole; Bermuda-Granex-Grano

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

... Washington State, which is outside of marketing order 958, has packed mixed colors of larger Walla Walla type... permitting mixed colors when designated as a specialty or mixed pack will facilitate the marketing of onions..., August 22, 2013 / Proposed Rules#0;#0; [[Page 52099

7 CFR 29.1036 - Mixed Group (M).

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 2 2011-01-01 2011-01-01 false Mixed Group (M). 29.1036 Section 29.1036 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1036 Mixed Group (M). This group consists of tobacco from three or more groups or two...

7 CFR 29.1036 - Mixed Group (M).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 2 2010-01-01 2010-01-01 false Mixed Group (M). 29.1036 Section 29.1036 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... Type 92) § 29.1036 Mixed Group (M). This group consists of tobacco from three or more groups or two...

7 CFR 29.2282 - Mixed color or variegated (M).

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 2 2013-01-01 2013-01-01 false Mixed color or variegated (M). 29.2282 Section 29.2282 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... 21) § 29.2282 Mixed color or variegated (M). Distinctly different colors of the type mingled together...

7 CFR 29.2282 - Mixed color or variegated (M).

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 2 2012-01-01 2012-01-01 false Mixed color or variegated (M). 29.2282 Section 29.2282 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... 21) § 29.2282 Mixed color or variegated (M). Distinctly different colors of the type mingled together...

7 CFR 29.2282 - Mixed color or variegated (M).

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 2 2014-01-01 2014-01-01 false Mixed color or variegated (M). 29.2282 Section 29.2282 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards... 21) § 29.2282 Mixed color or variegated (M). Distinctly different colors of the type mingled together...

Reliabilities of mental rotation tasks: limits to the assessment of individual differences.

PubMed

Hirschfeld, Gerrit; Thielsch, Meinald T; Zernikow, Boris

2013-01-01

Mental rotation tasks with objects and body parts as targets are widely used in cognitive neuropsychology. Even though these tasks are well established to study between-groups differences, the reliability on an individual level is largely unknown. We present a systematic study on the internal consistency and test-retest reliability of individual differences in mental rotation tasks comparing different target types and orders of presentations. In total n = 99 participants (n = 63 for the retest) completed the mental rotation tasks with hands, feet, faces, and cars as targets. Different target types were presented in either randomly mixed blocks or blocks of homogeneous targets. Across all target types, the consistency (split-half reliability) and stability (test-retest reliabilities) were good or acceptable both for intercepts and slopes. At the level of individual targets, only intercepts showed acceptable reliabilities. Blocked presentations resulted in significantly faster and numerically more consistent and stable responses. Mental rotation tasks-especially in blocked variants-can be used to reliably assess individual differences in global processing speed. However, the assessment of the theoretically important slope parameter for individual targets requires further adaptations to mental rotation tests.

Clinical characteristics and prognostic significance of 92 cases of patients with primary mixed-histology lung cancer.

PubMed

Deng, Pengbo; Hu, Chengping; Zhou, Lihua; Li, Yuanyuan; Huang, Li

2013-09-01

Mixed-histology primary lung cancer is a rare type of lung cancer, where data regarding epidemiology, clinical features and prognosis of survival are limited. The aim of this study was to analyze the clinical characteristics of patients with mixed-histology lung tumors, and to investigate the association between clinical characteristics, treatment and prognosis. Between January, 1999 and September, 2008, 1,842 patients were diagnosed with primary lung tumors. Of these, 92 presented a mixed histological pattern. Patient clinical characteristics, clinical tumor-node-metastasis (TNM) staging, diagnostic methods, treatment and survival data were collected in order to be retrospectively analyzed. Differences between the frequencies were examined using the χ 2 test and survival rates using the Kaplan-Meier method. The log-rank test was used to compare the survival curves and a probability value <5% (P<0.05) was considered to indicate a statistically significant difference. Of the 92 lung cancer patients (4.99%) with a mixed histological pattern, most were adenosquamous carcinomas. Patients included 75 men and 17 women with a mean age of 56 years. Most cases were in late stage and 64 patients had metastasis. The 1-, 2- and 3-year survival of 52 mixed-histology and 54 non-small cell lung cancer (NSCLC) patients with resection who were successfully followed up, was 63.5, 23.1, 9.6 and 81.5, 48.1, 27.7% (P=0.013). The median survival time of mixed-histology lung cancer patients treated with surgery plus adjuvant therapy and surgery alone was 22 and 12 months, respectively (P=0.002). Mixed-histology lung cancer is characterized by higher malignancy and poor prognosis. However, surgery plus adjuvant therapy is able to prolong survival, compared to surgery alone.

Use of multispectral satellite remote sensing to assess mixing of suspended sediment downstream of large river confluences

NASA Astrophysics Data System (ADS)

Umar, M.; Rhoads, Bruce L.; Greenberg, Jonathan A.

2018-01-01

Although past work has noted that contrasts in turbidity often are detectable on remotely sensed images of rivers downstream from confluences, no systematic methodology has been developed for assessing mixing over distance of confluent flows with differing surficial suspended sediment concentrations (SSSC). In contrast to field measurements of mixing below confluences, satellite remote-sensing can provide detailed information on spatial distributions of SSSC over long distances. This paper presents a methodology that uses remote-sensing data to estimate spatial patterns of SSSC downstream of confluences along large rivers and to determine changes in the amount of mixing over distance from confluences. The method develops a calibrated Random Forest (RF) model by relating training SSSC data from river gaging stations to derived spectral indices for the pixels corresponding to gaging-station locations. The calibrated model is then used to predict SSSC values for every river pixel in a remotely sensed image, which provides the basis for mapping of spatial variability in SSSCs along the river. The pixel data are used to estimate average surficial values of SSSC at cross sections spaced uniformly along the river. Based on the cross-section data, a mixing metric is computed for each cross section. The spatial pattern of change in this metric over distance can be used to define rates and length scales of surficial mixing of suspended sediment downstream of a confluence. This type of information is useful for exploring the potential influence of various controlling factors on mixing downstream of confluences, for evaluating how mixing in a river system varies over time and space, and for determining how these variations influence water quality and ecological conditions along the river.

Fuel-rich, catalytic reaction experimental results

NASA Technical Reports Server (NTRS)

Rollbuhler, R. James

1991-01-01

Future aeropropulsion gas turbine combustion requirements call for operating at very high inlet temperatures, pressures, and large temperature rises. At the same time, the combustion process is to have minimum pollution effects on the environment. Aircraft gas turbine engines utilize liquid hydrocarbon fuels which are difficult to uniformly atomize and mix with combustion air. An approach for minimizing fuel related problems is to transform the liquid fuel into gaseous form prior to the completion of the combustion process. Experimentally obtained results are presented for vaporizing and partially oxidizing a liquid hydrocarbon fuel into burnable gaseous components. The presented experimental data show that 1200 to 1300 K reaction product gas, rich in hydrogen, carbon monoxide, and light-end hydrocarbons, is formed when flowing 0.3 to 0.6 fuel to air mixes through a catalyst reactor. The reaction temperatures are kept low enough that nitrogen oxides and carbon particles (soot) do not form. Results are reported for tests using different catalyst types and configurations, mass flowrates, input temperatures, and fuel to air ratios.

The potential roles of biological soil crusts in dryland hydrologic cycles

USGS Publications Warehouse

Belnap, J.

2006-01-01

Biological soil crusts (BSCs) are the dominant living cover in many drylands of the world. They possess many features that can influence different aspects of local hydrologic cycles, including soil porosity, absorptivity, roughness, aggregate stability, texture, pore formation, and water retention. The influence of biological soil crusts on these factors depends on their internal and external structure, which varies with climate, soil, and disturbance history. This paper presents the different types of biological soil crusts, discusses how crust type likely influences various aspects of the hydrologic cycle, and reviews what is known and not known about the influence of biological crusts on sediment production and water infiltration versus runoff in various drylands around the world. Most studies examining the effect of biological soil crusts on local hydrology are done by comparing undisturbed sites with those recently disturbed by the researchers. Unfortunately, this greatly complicates interpretation of the results. Applied disturbances alter many soil features such as soil texture, roughness, aggregate stability, physical crusting, porosity, and bulk density in ways that would not necessarily be the same if crusts were not naturally present. Combined, these studies show little agreement on how biological crusts affect water infiltration or runoff. However, when studies are separated by biological crust type and utilize naturally occurring differences among these types, results indicate that biological crusts in hyperarid regions reduce infiltration and increase runoff, have mixed effects in and regions, and increase infiltration and reduce runoff in semiarid cool and cold drylands. However, more studies are needed before broad generalizations can be made on how biological crusts affect infiltration and runoff. We especially need studies that control for sub-surface soil features such as bulk density, micro- and macropores, and biological crust structure. Unlike the mixed effects of biological crusts on infiltration and runoff among regions, almost all studies show that biological crusts reduce sediment production, regardless of crust or dryland type.

The potential roles of biological soil crusts in dryland hydrologic cycles

NASA Astrophysics Data System (ADS)

Belnap, Jayne

2006-10-01

Biological soil crusts (BSCs) are the dominant living cover in many drylands of the world. They possess many features that can influence different aspects of local hydrologic cycles, including soil porosity, absorptivity, roughness, aggregate stability, texture, pore formation, and water retention. The influence of biological soil crusts on these factors depends on their internal and external structure, which varies with climate, soil, and disturbance history. This paper presents the different types of biological soil crusts, discusses how crust type likely influences various aspects of the hydrologic cycle, and reviews what is known and not known about the influence of biological crusts on sediment production and water infiltration versus runoff in various drylands around the world. Most studies examining the effect of biological soil crusts on local hydrology are done by comparing undisturbed sites with those recently disturbed by the researchers. Unfortunately, this greatly complicates interpretation of the results. Applied disturbances alter many soil features such as soil texture, roughness, aggregate stability, physical crusting, porosity, and bulk density in ways that would not necessarily be the same if crusts were not naturally present. Combined, these studies show little agreement on how biological crusts affect water infiltration or runoff. However, when studies are separated by biological crust type and utilize naturally occurring differences among these types, results indicate that biological crusts in hyperarid regions reduce infiltration and increase runoff, have mixed effects in arid regions, and increase infiltration and reduce runoff in semiarid cool and cold drylands. However, more studies are needed before broad generalizations can be made on how biological crusts affect infiltration and runoff. We especially need studies that control for sub-surface soil features such as bulk density, micro- and macropores, and biological crust structure. Unlike the mixed effects of biological crusts on infiltration and runoff among regions, almost all studies show that biological crusts reduce sediment production, regardless of crust or dryland type.

Occurrence Characteristics of Microplastic in Secondary Sewage Treatment Plant in Shanghai,China.

NASA Astrophysics Data System (ADS)

Bai, M.; Zhao, S.; Li, D.

2017-12-01

As emerging pollutants, microplastics (MPs) are of concern worldwide. Due to plenty of microbeads and synthetic fibers presenting in the effluent of waste water treatment plants (WWTPs), WWTPs have been regarded as important point sources of MP into the sea. Currently, information of microplastics from WWTPs in China is limited. Herein, we studied the MP contamination of a sewage plant in Shanghai by analyzing water and sludge samples with fourier transform infrared spectroscopy. The abundances of MP in the influent, mixed water, effluent and sludge four stages are respectively 117 n/L, 90 n/L, 52 n/L and 181 n/50g(wet weight). The removal efficiency of MP in the current WWTP is 55.6%. Fiber is the most common shape type. Rayon is the most type in effluent and mixed water while synthetic leather account for the largest percentage in influent and sludge. This study firstly discussed the occurrence characteristics of microplastics in the WWTP of China and confirmed that WWTP is a source of MPs inputting into aquatic environments.

Discrete-continuous variable structural synthesis using dual methods

NASA Technical Reports Server (NTRS)

Schmit, L. A.; Fleury, C.

1980-01-01

Approximation concepts and dual methods are extended to solve structural synthesis problems involving a mix of discrete and continuous sizing type of design variables. Pure discrete and pure continuous variable problems can be handled as special cases. The basic mathematical programming statement of the structural synthesis problem is converted into a sequence of explicit approximate primal problems of separable form. These problems are solved by constructing continuous explicit dual functions, which are maximized subject to simple nonnegativity constraints on the dual variables. A newly devised gradient projection type of algorithm called DUAL 1, which includes special features for handling dual function gradient discontinuities that arise from the discrete primal variables, is used to find the solution of each dual problem. Computational implementation is accomplished by incorporating the DUAL 1 algorithm into the ACCESS 3 program as a new optimizer option. The power of the method set forth is demonstrated by presenting numerical results for several example problems, including a pure discrete variable treatment of a metallic swept wing and a mixed discrete-continuous variable solution for a thin delta wing with fiber composite skins.

The crystal structure of the mixed-layer Aurivillius phase Bi 5Ti 1.5W 1.5O 15

NASA Astrophysics Data System (ADS)

Tellier, J.; Boullay, Ph.; Créon, N.; Mercurio, D.

2005-09-01

The crystal structure of the 1+2 mixed-layer Aurivillius phase Bi 5Ti 1.5W 1.5O 15 (SG I2cm n o 46: -cba, Z=4, a=5.4092(3) Å, b=5.3843(3) Å and c=41.529(3) Å) consisting of the ordered intergrowth of one and two octahedra thick perovskite-type blocks separated by [Bi 2O 2] 2+ slabs is reported. Supported by an electron diffraction investigation and, using the Rietveld analysis, it is shown that this compound should be described using a I-centering lattice in agreement with the generalised structural model of the Aurivillius type compounds recently presented by the authors. The structure of this Bi 5Ti 1.5W 1.5O 15 phase is analyzed in comparison with the related simple members (Bi 2WO 6 and Bi 3Ti 1.5W 0.5O 9). The crystal structure of Bi 3Ti 1.5W 0.5O 9 is also reported.

The environmental impacts of foamed concrete production and exploitation

NASA Astrophysics Data System (ADS)

Namsone, E.; Korjakins, A.; Sahmenko, G.; Sinka, M.

2017-10-01

This paper presents a study focusing on the environmental impacts of foamed concrete production and exploitation. CO2 emissions are very important factor for describing durability and sustainability of any building material and its life cycle. The building sector is one of the largest energy-consuming sectors in the world. In this study CO2 emissions are evaluated with regard to three types of energy resources (gas, coal and eco-friendly fuel). The related savings on raw materials are up to 120 t of water per 1000 t of traditionally mixed foamed concrete and up to 350 t of sand per 1000 t of foamed concrete produced with intensive mixing technology. In addition, total reduction of CO2 emissions (up to 60 t per 1000 m3 of material) and total energy saving from introduction of foamed concrete production (depending on the type of fuel) were calculated. In order to analyze the conditions of exploitation, both thermal conductivity and thickness of wall was determined. All obtained and calculated results were compared to those of the commercially produced autoclaved aerated concrete.

Petroleum systems of the San Joaquin Basin Province -- geochemical characteristics of gas types: Chapter 10 in Petroleum systems and geologic assessment of oil and gas in the San Joaquin Basin Province, California

USGS Publications Warehouse

Lillis, Paul G.; Warden, Augusta; Claypool, George E.; Magoon, Leslie B.

2008-01-01

The San Joaquin Basin Province is a petroliferous basin filled with predominantly Late Cretaceous to Pliocene-aged sediments, with organic-rich marine rocks of Late Cretaceous, Eocene, and Miocene age providing the source of most of the oil and gas. Previous geochemical studies have focused on the origin of the oil in the province, but the origin of the natural gas has received little attention. To identify and characterize natural gas types in the San Joaquin Basin, 66 gas samples were analyzed and combined with analyses of 15 gas samples from previous studies. For the purpose of this resource assessment, each gas type was assigned to the most likely petroleum system. Three general gas types are identified on the basis of bulk and stable carbon isotopic composition—thermogenic dry (TD), thermogenic wet (TW) and biogenic (B). The thermogenic gas types are further subdivided on the basis of the δ13C values of methane and ethane and nitrogen content into TD-1, TD-2, TD-Mixed, TW-1, TW-2, and TW-Mixed. Gas types TD-1 and TD-Mixed, a mixture of biogenic and TD-1 gases, are produced from gas fields in the northern San Joaquin Basin. Type TD-1 gas most likely originated from the Late Cretaceous to Paleocene Moreno Formation, a gas-prone source rock. The biogenic component of the TD-Mixed gas existed in the trap prior to the influx of thermogenic gas. For the assessment, these gas types were assigned to the Winters- Domengine Total Petroleum System, but subsequent to the assessment were reclassified as part of the Moreno-Nortonville gas system. Dry thermogenic gas produced from oil fields in the southern San Joaquin Basin (TD-2 gas) most likely originated from the oil-prone source rock of Miocene age. These samples have low wetness values due to migration fractionation or biodegradation. The thermogenic wet gas types (TW-1, TW-2, TW-Mixed) are predominantly associated gas produced from oil fields in the southern and central San Joaquin Basin. Type TW-1 gas most likely originates from source rocks within the Eocene Kreyenhagen Formation or the Eocene Tumey formation of Atwill (1935). Type TW-2 gas most likely originates from the Miocene Monterey Formation and equivalents. TW-Mixed gas is likely a mixture of biogenic and wet thermogenic gas (TW-1 or TW-2) derived from source rocks mentioned above. The thermogenic wet gas types are included in the corresponding Eocene or Miocene total petroleum systems. Type B gas is a dry, nonassociated gas produced from the Pliocene San Joaquin Formation in the central and southern San Joaquin Basin. This gas type most likely originated from Pliocene marine source rocks as a product of methanogenesis, and defines the Neogene Nonassociated Gas Total Petroleum System.

Blood Mixing Upregulates Platelet Membrane-Bound CD40 Ligand Expression in vitro Independent of Abo Compatibility.

PubMed

Huang, Go-Shine; Hu, Mei-Hua; Lin, Tso-Chou; Lin, Yi-Chang; Tsai, Yi-Ting; Lin, Chih-Yuan; Ke, Hung-Yen; Zheng, Xu-Zhi; Tsai, Chien-Sung

2017-11-30

Platelets play a central role in the inflammation response via CD40 ligand (CD40L) expression, which may lead to transfusion reactions. The precise role of platelet CD40L-mediated inflammation in transfusion reactions is unclear. Therefore, we assessed the effects of in vitro blood mixing on platelet CD40L expression. In addition, we examined the effect of ABO compatibility on CD40L expression. Donor packed red blood cells were acquired from a blood bank, and recipient blood was obtained from patients undergoing cardiac surgery and prepared as washed platelets. Donor blood was mixed with suspended, washed recipient platelets to obtain a final mixing ratio of 1%, 5%, or 10% (vol/vol). The blood mixtures were divided into three groups: Group M, cross-matched blood-type mixing (n = 20); Group S, ABO type-specific uncross-matched blood (n = 20); and Group I, ABO incompatibility (not ABO type-specific blood and not process cross-matched) mixing (n = 20). The blood mixtures were used to detect platelet membrane-bound CD40L expression by flow cytometry. Blood mixing resulted in an increase in CD40L expression in Group M (P < 0.001), Group S (P < 0.001), and Group I (P < 0.001). CD40L expression following blood mixing potentially led to a transfusion reaction in each of the groups. There were no differences in CD40L expression among the three groups (P = 0.988) correlated with ABO compatibility or incompatibility. This indicates that the reactions between red blood cell surface antigens and plasma antibodies do not play a role in the induction of CD40L expression.

Ash effects on the thermal conductivity of a mediterranean loam soil

NASA Astrophysics Data System (ADS)

Rubio, Carles; Pereira, Paulo; Ubeda, Xavier

2014-05-01

The purpose of this work is to explore the variability on the soil thermal conductivity for a burnt soil and assessing the effects of the ashes on the heat transfer when they were incorporated into the soil matrix. A set of 42 soil samples from the Montgrí massif experimental plot between surface and 5 cm depth was collected before and after the soil was burnt. A thermal characterization of the soil was carried out. For that a dry out curve was constructed, which presented the relationship between water content and thermal conductivity for both types of soil samples, burnt and non-burnt soil. The results shown changes in the heat pulse transfer, being more conductive the soil before to be burnt (0.378 W•m-1•C-1) than the soil after to be exposed to the fire (0.337 W•m-1•C-1). Indeed, on the whole of moisture scenarios the values of thermal conductivity decreased after soil was burnt. Another experimental concern was based on to observe the soil thermal behaviour when ash collected after fire was incorporated into the burnt soil matrix. In this case, soil thermal and soil hydrodynamic behaviour presented differences according to the type of ash. Soil mixed with fly ash showed higher thermal conductivity than soil mixed with bottom ash. To sum up; the soil thermal conductivity decreased when soil was burnt. On the other hand, soil thermal conductivity shown differences depending on the type of ash incorporated into the matrix. Fly ash transferred the heat pulse better than bottom ash.

The Marketing Mix and Development of Medical Tourism in Shiraz

PubMed Central

Jabbari, Alireza; Rahimi Zarchi, Mohammad Kazem; Kavosi, Zahra; Shafaghat, Tahere; Keshtkaran, Ali

2013-01-01

Introduction: In recent years, medical tourism market has been raised as one of the income-earning and competitive industries in the world and is considered as a modern field of advanced tourism. Therefore, a great number of countries are seeking to develop this type of tourism and one of the strategies for developing this industry is using the marketing mix elements. Methods: This study was a descriptive-analytic and cross sectional one. The research community included all the public and private hospitals of Shiraz among which, 7 public and 9 private hospitals were studied. The study data were collected through a researcher-made check list whose face and content validity was confirmed by the experts. Then, the data were entered into the SPSS statistical software. According to the objectives of the study, the descriptive results were presented in frequency tables and Chi-square test was used for data analysis. In addition, P<0.05 was considered as statistically significant. Results: According to the results, both public and private hospitals of Shiraz were in the best condition regarding staff and physician mix and in the worst condition concerning promoting and facilities mixes. No significant difference was found between public and private hospitals regarding the mixes. Conclusion: From marketing mix elements view, paying more attention to media advertisements and providing more facilities can improve the status of the hospitals which, consequently, results in attracting more medical tourists and developing this industry in Shiraz. PMID:23678337

Effect of new type of synthetic waxes on reduced production and compaction temperature of asphalt mixture with reclaimed asphalt

NASA Astrophysics Data System (ADS)

Valentová, Tereza; Benešová, Lucie; Mastný, Jan; Valentin, Jan

2017-09-01

Lower mixing and paving temperatures of asphalt mixtures, which are an important issue in recent years, with respect to increased energy demand of civil engineering structures during their processing, allow reduction of this demand and result in minimized greenhouse gas production. In present time, there are many possibilities how to achieve reduction of production temperature during the mixing and paving of an asphalt mixture. The existing solutions distinguish in target operating temperature behaviour which has to be achieved in terms of good workability. This paper is focused on technical solutions based on use of new types of selected synthetic and bio-based waxes. In case of bio-based additive sugar cane wax was used, which is free of paraffins and is reclaimed as waste product during processing of sugar cane. The used waxes are added to bituminous binder in form of free-flowing granules or fine-grained powder. Synthetic waxes are represented by new series of Fischer-Tropsch wax in form of fine granules as well as by polyethylene waxes in form of fine-grained powder or granules. Those waxes were used to modify a standard paving grade bitumen dosed into asphalt mixture of ACsurf type containing up to 30 % of reclaimed asphalt (RA).

Comparing a single case to a control group - Applying linear mixed effects models to repeated measures data.

PubMed

Huber, Stefan; Klein, Elise; Moeller, Korbinian; Willmes, Klaus

2015-10-01

In neuropsychological research, single-cases are often compared with a small control sample. Crawford and colleagues developed inferential methods (i.e., the modified t-test) for such a research design. In the present article, we suggest an extension of the methods of Crawford and colleagues employing linear mixed models (LMM). We first show that a t-test for the significance of a dummy coded predictor variable in a linear regression is equivalent to the modified t-test of Crawford and colleagues. As an extension to this idea, we then generalized the modified t-test to repeated measures data by using LMMs to compare the performance difference in two conditions observed in a single participant to that of a small control group. The performance of LMMs regarding Type I error rates and statistical power were tested based on Monte-Carlo simulations. We found that starting with about 15-20 participants in the control sample Type I error rates were close to the nominal Type I error rate using the Satterthwaite approximation for the degrees of freedom. Moreover, statistical power was acceptable. Therefore, we conclude that LMMs can be applied successfully to statistically evaluate performance differences between a single-case and a control sample. Copyright © 2015 Elsevier Ltd. All rights reserved.

Determining vehicle operating speed and lateral position along horizontal curves using linear mixed-effects models.

PubMed

Fitzsimmons, Eric J; Kvam, Vanessa; Souleyrette, Reginald R; Nambisan, Shashi S; Bonett, Douglas G

2013-01-01

Despite recent improvements in highway safety in the United States, serious crashes on curves remain a significant problem. To assist in better understanding causal factors leading to this problem, this article presents and demonstrates a methodology for collection and analysis of vehicle trajectory and speed data for rural and urban curves using Z-configured road tubes. For a large number of vehicle observations at 2 horizontal curves located in Dexter and Ames, Iowa, the article develops vehicle speed and lateral position prediction models for multiple points along these curves. Linear mixed-effects models were used to predict vehicle lateral position and speed along the curves as explained by operational, vehicle, and environmental variables. Behavior was visually represented for an identified subset of "risky" drivers. Linear mixed-effect regression models provided the means to predict vehicle speed and lateral position while taking into account repeated observations of the same vehicle along horizontal curves. Speed and lateral position at point of entry were observed to influence trajectory and speed profiles. Rural horizontal curve site models are presented that indicate that the following variables were significant and influenced both vehicle speed and lateral position: time of day, direction of travel (inside or outside lane), and type of vehicle.

Psychophysical estimation of 3D virtual depth of united, synthesized and mixed type stereograms by means of simultaneous observation

NASA Astrophysics Data System (ADS)

Iizuka, Masayuki; Ookuma, Yoshio; Nakashima, Yoshio; Takamatsu, Mamoru

2007-02-01

Recently, many types of computer-generated stereograms (CGSs), i.e. various works of art produced by using computer are published for hobby and entertainment. It is said that activation of brain, improvement of visual eye sight, decrease of mental stress, effect of healing, etc. are expected when properly appreciating a kind of CGS as the stereoscopic view. There is a lot of information on the internet web site concerning all aspects of stereogram history, science, social organization, various types of stereograms, and free software for generating CGS. Generally, the CGS is classified into nine types: (1) stereo pair type, (2) anaglyph type, (3) repeated pattern type, (4) embedded type, (5) random dot stereogram (RDS), (6) single image stereogram (SIS), (7) united stereogram, (8) synthesized stereogram, and (9) mixed or multiple type stereogram. Each stereogram has advantages and disadvantages when viewing directly the stereogram with two eyes by training with a little patience. In this study, the characteristics of united, synthesized and mixed type stereograms, the role and composition of depth map image (DMI) called hidden image or picture, and the effect of irregular shift of texture pattern image called wall paper are discussed from the viewpoint of psychophysical estimation of 3D virtual depth and visual quality of virtual image by means of simultaneous observation in the case of the parallel viewing method.

Evaluation of Parotid Salivary Glucose Level for Clinical Diagnosis and Monitoring Type 2 Diabetes Mellitus Patients

PubMed Central

Wang, Beibei; Du, Juan; Zhu, Zhao; Ma, Zhihong; Wang, Songlin

2017-01-01

Background. To investigate the relationships among blood glucose, mixed saliva glucose, and parotid glucose in type 2 diabetes patients and to evaluate the diagnostic and monitoring value of salivary gland glucose in patients with type 2 diabetes (type 2DM). Material and Methods. Thirty patients with type 2DM and 30 healthy age- and sex-matched individuals were included in this study. Glucose levels in unstimulated mixed saliva and in unstimulated parotid saliva were measured by the glucose oxidase peroxidase method. Results. The blood glucose and parotid salivary glucose levels in type 2DM patients were significantly higher than those in the controls (P < 0.05). The blood glucose, parotid salivary glucose, and mixed salivary glucose were 7.46 ± 1.44 mmol/L, 0.18 ± 0.19 mmol/L, and 3.17 × 10−2 ± 2.84 × 10−2 mmol/L, respectively, in the type 2DM group; the corresponding glucose levels in the control group were 5.56 ± 0.71 mmol/L, 7.70 × 10−2 ± 6.02 × 10−2 mmol/L, and 3.47 × 10−2 ± 2.79 × 10−2 mmol/L. The parotid salivary and blood glucose levels in type 2DM patients were strongly correlated; the linear regression equation for blood glucose and parotid salivary glucose was Y = 6.267X + 6.360, with r = 0.810. However, mixed salivary glucose levels were not significantly different in the type 2 diabetes group compared with the control group. Conclusion. Our results suggest that parotid salivary glucose has potential as a biomarker to monitor type 2DM and as a painless, noninvasive method for the management of type 2DM. PMID:28251153

Sensitive sub-Doppler nonlinear spectroscopy for hyperfine-structure analysis using simple atomizers

NASA Astrophysics Data System (ADS)

Mickadeit, Fritz K.; Kemp, Helen; Schafer, Julia; Tong, William M.

1998-05-01

Laser wave-mixing spectroscopy is presented as a sub-Doppler method that offers not only high spectral resolution, but also excellent detection sensitivity. It offers spectral resolution suitable for hyperfine structure analysis and isotope ratio measurements. In a non-planar backward- scattering four-wave mixing optical configuration, two of the three input beams counter propagate and the Doppler broadening is minimized, and hence, spectral resolution is enhanced. Since the signal is a coherent beam, optical collection is efficient and signal detection is convenient. This simple multi-photon nonlinear laser method offers un usually sensitive detection limits that are suitable for trace-concentration isotope analysis using a few different types of simple analytical atomizers. Reliable measurement of hyperfine structures allows effective determination of isotope ratios for chemical analysis.

Terminal shock position and restart control of a Mach 2.7, two-dimensional, twin duct mixed compression inlet

NASA Technical Reports Server (NTRS)

Cole, G. L.; Neiner, G. H.; Baumbick, R. J.

1973-01-01

Experimental results of terminal shock and restart control system tests of a two-dimensional, twin-duct mixed compression inlet are presented. High-response (110-Hz bandwidth) overboard bypass doors were used, both as the variable to control shock position and as the means of disturbing the inlet airflow. An inherent instability in inlet shock position resulted in noisy feedback signals and thus restricted the terminal shock position control performance that was achieved. Proportional-plus-integral type controllers using either throat exit static pressure or shock position sensor feedback gave adequate low-frequency control. The inlet restart control system kept the terminal shock control loop closed throughout the unstart-restart transient. The capability to restart the inlet was non limited by the inlet instability.

Recent Studies on Metal Oxides as Anodes for Li-ION Batteries

NASA Astrophysics Data System (ADS)

Sharma, N.; Subba Rao, G. V.; Chowdari, B. V. R.

Commercial lithium ion batteries (LIB) use layer-type compounds as the electrode materials and Li-ion conducting liquid or polymeric gel as the electrolyte. The preferred cathode and anode are LiCoO2 and graphite respectively. Efforts to improve the performance as well as safety-in-operation of LIB led to the search for alternate electrode materials. As regards the anodes, metal-oxide systems received special attention: Tin (Sn) containing mixed oxides and various 3d- and 4d- transition metal (M) mixed oxides. The reversible capacities in these systems arise either from alloying/de-alloying, formation/decomposition of Li2O aided by the nanosize metal (M) particles/Li-M-O bronze or Li-intercalation/de-intercalation. A brief account of the recent studies is presented.

Developing Mixed Reality Educational Applications: The Virtual Touch Toolkit.

PubMed

Mateu, Juan; Lasala, María José; Alamán, Xavier

2015-08-31

In this paper, we present Virtual Touch, a toolkit that allows the development of educational activities through a mixed reality environment such that, using various tangible elements, the interconnection of a virtual world with the real world is enabled. The main goal of Virtual Touch is to facilitate the installation, configuration and programming of different types of technologies, abstracting the creator of educational applications from the technical details involving the use of tangible interfaces and virtual worlds. Therefore, it is specially designed to enable teachers to themselves create educational activities for their students in a simple way, taking into account that teachers generally lack advanced knowledge in computer programming and electronics. The toolkit has been used to develop various educational applications that have been tested in two secondary education high schools in Spain.

Symmetric Fold/Super-Hopf Bursting, Chaos and Mixed-Mode Oscillations in Pernarowski Model of Pancreatic Beta-Cells

NASA Astrophysics Data System (ADS)

Fallah, Haniyeh

Pancreatic beta-cells produce insulin to regularize the blood glucose level. Bursting is important in beta cells due to its relation to the release of insulin. Pernarowski model is a simple polynomial model of beta-cell activities indicating bursting oscillations in these cells. This paper presents bursting behaviors of symmetric type in this model. In addition, it is shown that the current system exhibits the phenomenon of period doubling cascades of canards which is a route to chaos. Canards are also observed symmetrically near folds of slow manifold which results in a chaotic transition between n and n + 1 spikes symmetric bursting. Furthermore, mixed-mode oscillations (MMOs) and combination of symmetric bursting together with MMOs are illustrated during the transition between symmetric bursting and continuous spiking.

Evaluation of steel slag coarse aggregate in hot mix asphalt concrete.

PubMed

Ahmedzade, Perviz; Sengoz, Burak

2009-06-15

This paper presents the influences of the utilization of steel slag as a coarse aggregate on the properties of hot mix asphalt. Four different asphalt mixtures containing two types of asphalt cement (AC-5; AC-10) and coarse aggregate (limestone; steel slag) were used to prepare Marshall specimens and to determine optimum bitumen content. Mechanical characteristics of all mixtures were evaluated by Marshall stability, indirect tensile stiffness modulus, creep stiffness, and indirect tensile strength tests. The electrical sensitivity of the specimens were also investigated in accordance with ASTM D257-91. It was observed that steel slag used as a coarse aggregate improved the mechanical properties of asphalt mixtures. Moreover, volume resistivity values demonstrated that the electrical conductivity of steel slag mixtures were better than that of limestone mixtures.

Mikado: A graphic program

NASA Astrophysics Data System (ADS)

Secretan, Y.

A discussion of the modular program Mikado is presented. Mikado was developed with the goal of creating a flexible graphic tool to display and help analyze the results of finite element fluid flow computations. Mikado works on unstructured meshes, with elements of mixed geometric type, but also offers the possibility of using structured meshes. The program can be operated by both menu and mouse (interactive), or by command file (batch). Mikado is written in FORTRAN, except for a few system dependent subroutines which are in C. It runs presently on Silicon Graphics' workstations and could be easily ported to the IBM-RISC System/6000 family of workstations.

Showcase your service: social media and marketing basics in a dynamic, over-populated, mixed-message, and highly competitive world.

PubMed

Kuechel, Marie Czenko

2010-11-01

This article discusses social media as a means of communication between the aesthetic medical practice and clients. Discussion of the various types of social media and how each can support a physician's practice, brand, market, and tolerances is presented. Blogs, wikis, networks, viral marketing, and electronic communications are presented in terms of what they can provide a practice and their limitations and pitfalls. Emphasis is on finding the combination of methods to showcase the individual style and personality of a practice. Copyright © 2010 Elsevier Inc. All rights reserved.

Development and Validation of a 3-Dimensional CFB Furnace Model

NASA Astrophysics Data System (ADS)

Vepsäläinen, Arl; Myöhänen, Karl; Hyppäneni, Timo; Leino, Timo; Tourunen, Antti

At Foster Wheeler, a three-dimensional CFB furnace model is essential part of knowledge development of CFB furnace process regarding solid mixing, combustion, emission formation and heat transfer. Results of laboratory and pilot scale phenomenon research are utilized in development of sub-models. Analyses of field-test results in industrial-scale CFB boilers including furnace profile measurements are simultaneously carried out with development of 3-dimensional process modeling, which provides a chain of knowledge that is utilized as feedback for phenomenon research. Knowledge gathered by model validation studies and up-to-date parameter databases are utilized in performance prediction and design development of CFB boiler furnaces. This paper reports recent development steps related to modeling of combustion and formation of char and volatiles of various fuel types in CFB conditions. Also a new model for predicting the formation of nitrogen oxides is presented. Validation of mixing and combustion parameters for solids and gases are based on test balances at several large-scale CFB boilers combusting coal, peat and bio-fuels. Field-tests including lateral and vertical furnace profile measurements and characterization of solid materials provides a window for characterization of fuel specific mixing and combustion behavior in CFB furnace at different loads and operation conditions. Measured horizontal gas profiles are projection of balance between fuel mixing and reactions at lower part of furnace and are used together with both lateral temperature profiles at bed and upper parts of furnace for determination of solid mixing and combustion model parameters. Modeling of char and volatile based formation of NO profiles is followed by analysis of oxidizing and reducing regions formed due lower furnace design and mixing characteristics of fuel and combustion airs effecting to formation ofNO furnace profile by reduction and volatile-nitrogen reactions. This paper presents CFB process analysis focused on combustion and NO profiles in pilot and industrial scale bituminous coal combustion.

Lead mobilization during tectonic reactivation of the western Baltic Shield

DOE Office of Scientific and Technical Information (OSTI.GOV)

Romer, R.L.; Wright, J.E.

Lead isotope data from sulfide deposits of the western part of the Baltic Shield define mixing lines in the [sup 206]Pb/[sup 204]Pb-[sup 207]Pb/[sup 204]Pb diagram. Lead from two types of sulfide deposits have been investigated: (1) Exhalative and volcanogenic deposits that are syngenetic with their host rocks; and (2) vein deposits. The syngenetic deposits locally show a very wide range of lead isotopic compositions that reflect a variable addition of highly radiogenic lead, while the vein deposits, although they have radiogenic lead isotopic compositions, exhibit only limited isotopic variations. In different provinces of the shield, both types of deposits fallmore » on the same lead mixing array. The slope of the lead mixing lines varies as a function of the age of basement rocks and the age of the tectonic event which produced the lead mobilization and therefore relates the source rock age with the age of lead mobilization. Calculated mixing ages fall into several short time periods that correspond either to orogenic events or to major phases of continental rifting. The orogenic events are the ca 360--430 Ma Caledonian, ca 900--1100 Ma Sveconorwegian, and the ca 1800--1900 Ma Svecofennian orogenic cycles. The rifting events correspond to the formation of the ca 280 Ma Oslo rift and the Ordovician (ca 450 Ma) graben system in the area of the present Gulf of Bothnia. Each mixing age indicates that lead was mobilized, probably as a consequence of mild thermal disturbances, and that the crust was permeable to lead migration. The data show that the geographic distribution of sulfide deposits with highly radiogenic lead isotopic compositions coincides with old graben systems, orogenic belts, and orogenic forelands on the Baltic Shield. The ages of vein deposits and their geographic distribution demonstrate multiple tectonic reactivation of the interior of the Baltic Shield in response to orogenic events at its margin. 68 refs., 6 refs., 4 tabs.« less

Feeding preference and daily ration of 12 dominant copepods on mono and mixed diets of phytoplankton, rotifers, and detritus in a tropical coastal water.

PubMed

Jagadeesan, L; Jyothibabu, R; Arunpandi, N; Anjusha, A; Parthasarathi, S; Pandiyarajan, R S

2017-09-11

Results of the experimental studies on the feeding habit and daily ration (DR) of 12 dominant copepods from a tropical coastal water (off Kochi, Southwest coast of India) on different food items (phytoplankton, rotifers, and detritus) are presented. Even though, all species of copepods consumed all types of food items in the experiments, they showed noticeable feeding preferences, having important ecological implications. Calanoid Paracalanus parvus and Acrocalanus gracilis consumed phytoplankton and rotifers equally in mono diets (74-89% of DR) and mixed diets (53-82% of DR), which indicated their ability to shift their diet in natural environment based on the availability of food items. Calanoid Acartia erythraea and A. danae consumed more phytoplankton (DR 83 and 72%, respectively) than rotifers (DR 51 and 46%, respectively) in mono diets, and in mixed diets, their consumption was high in phytoplankton combined food mixtures (P + R DR and P + D DR) rather than the R + D food type, indicated their preference for mixed diets of phytoplankton. Similarly, Calanoid Temora turbinata, Pseudodiaptomus serricaudatus, and Centropages tenuiremis preferred a herbivorous diet as evidenced by their high ingestion rate on phytoplankton mono (70 to 87% to their DR) and mixed diets (58 to 80% of DR). On the other hand, Cyclopoid Oithona similis and Poecilostomatoid Corycaeus danae preferred a carnivorous diet, consuming more rotifers (> 80% of DR) than phytoplankton (18-20% of DR) and detritus (5-6% of DR). Harpacticoids Macrosetella gracilis and Euterpina acutifrons equally preferred phytoplankton (78-92% of DR) and detritus (65-89% of DR). The study showed that the dominant copepods in the coastal waters off Kochi occupy different trophic niches available in the environment, which may be applicable in other similar environments as well.

Casualty Handling Simulation Using the Scenario-based Engineering Process

DTIC Science & Technology

2000-02-28

HERPES ZOSTER ENCEPHALITIS HEPATITIS INFECTIOUS VIRAL ANIMAL BITES/RABIES EXPOSURE MUMPS INFECTIOUS MONONUCLEOSIS TRACHOMA STD-SYPHILIS STD...casualties as they flow through the system. Identifying the proper mix is complicated by many factors, including the specific casualty stream, the...casualties as they flow through the system. Identifying the proper mix is complicated by its dependence on mission types. For example, the types and

Rapid increase in log populations in drought-stressed mixed-conifer and ponderosa pine forests in northern Arizona

Treesearch

Joseph L. Ganey; Scott C. Vojta

2012-01-01

Down logs provide important ecosystem services in forests and affect surface fuel loads and fire behavior. Amounts and kinds of logs are influenced by factors such as forest type, disturbance regime, forest man-agement, and climate. To quantify potential short-term changes in log populations during a recent global- climate-change type drought, we sampled logs in mixed-...

The properties of pellets from mixing bamboo and rice straw

Treesearch

Zhijia Liu; Xing' e Liu; Benhua Fei; Zehui Jiang; Zhiyong Cai; Yan Yu

2013-01-01

Rice straw pellets are the main type of biomass solid fuel and have great potential as a bioenergy resource of the future in China. But it also showed important problems because of its high content of ashes and its low gross calorific value, reducing the possibility to be used in domestic heating. It was certified that mixing different types of biomass materials was...

Epiphytic lichen diversity and biomass in low-elevation forests of the eastern Washington Cascade range, USA.

Treesearch

John F. Lehmkuhl

2004-01-01

cover types in the eastern Washington Cascade range. Cover types represented a temperature/moisture and stand structural complexity gradient. Lichen litterfall biomass increased with increasing stand complexity and moisture. Lichen litterfall biomass was 3.42 kg/ha in open pine stands, 7.51 kg/ha in young mixed-species stands, 8.55 kg/ha in mature mixed-species stands...

A comparison of loblolly pine growth and yield on pure pine and mixed pine-hardwood sites

Treesearch

James D. Haywood; John R. Toliver

1989-01-01

The case histories of four loblolly pine (Pinus taeda L.) sites were examined to determine if differences in growth and yield could be associated with stand type. The stand types were pure loblolly pine and mixed loblolly pine-hardwood. All sites were located on silt loam soils and mechanical site preparation was carried out on all sites before...

Effects of prescribed burning and litter type on litter decomposition and nutrient release in mixed-grass prairie in Eastern Montana

USDA-ARS?s Scientific Manuscript database

Fire can affect litter decomposition and carbon (C) and nitrogen (N) dynamics. Here, we examined the effect of summer fire and three litter types on litter decomposition and litter C and N dynamics in a northern mixed-grass prairie over a 24 month period starting ca. 14 months after fire. Over all...

Single-particle characterization of ice-nucleating particles and ice particle residuals sampled by three different techniques

NASA Astrophysics Data System (ADS)

Worringen, A.; Kandler, K.; Benker, N.; Dirsch, T.; Weinbruch, S.; Mertes, S.; Schenk, L.; Kästner, U.; Frank, F.; Nillius, B.; Bundke, U.; Rose, D.; Curtius, J.; Kupiszewski, P.; Weingartner, E.; Schneider, J.; Schmidt, S.; Ebert, M.

2014-09-01

In the present work, three different techniques are used to separate ice-nucleating particles (INP) and ice particle residuals (IPR) from non-ice-active particles: the Ice Selective Inlet (ISI) and the Ice Counterflow Virtual Impactor (Ice-CVI), which sample ice particles from mixed phase clouds and allow for the analysis of the residuals, as well as the combination of the Fast Ice Nucleus Chamber (FINCH) and the Ice Nuclei Pumped Virtual Impactor (IN-PCVI), which provides ice-activating conditions to aerosol particles and extracts the activated ones for analysis. The collected particles were analyzed by scanning electron microscopy and energy-dispersive X-ray microanalysis to determine their size, chemical composition and mixing state. Samples were taken during January/February 2013 at the High Alpine Research Station Jungfraujoch. All INP/IPR-separating techniques had considerable abundances (median 20-70%) of contamination artifacts (ISI: Si-O spheres, probably calibration aerosol; Ice-CVI: Al-O particles; FINCH + IN-PCVI: steel particles). Also, potential measurement artifacts (soluble material) occurred (median abundance < 20%). After removal of the contamination particles, silicates and Ca-rich particles, carbonaceous material and metal oxides were the major INP/IPR particle types separated by all three techniques. Minor types include soot and Pb-bearing particles. Sea-salt and sulfates were identified by all three methods as INP/IPR. Lead was identified in less than 10% of the INP/IPR. It was mainly present as an internal mixture with other particle types, but also external lead-rich particles were found. Most samples showed a maximum of the INP/IPR size distribution at 400 nm geometric diameter. In a few cases, a second super-micron maximum was identified. Soot/carbonaceous material and metal oxides were present mainly in the submicron range. ISI and FINCH yielded silicates and Ca-rich particles mainly with diameters above 1 μm, while the Ice-CVI also sampled many submicron particles. Probably owing to the different meteorological conditions, the INP/IPR composition was highly variable on a sample to sample basis. Thus, some part of the discrepancies between the different techniques may result from the (unavoidable) non-parallel sampling. The observed differences of the particles group abundances as well as the mixing state of INP/IPR point to the need of further studies to better understand the influence of the separating techniques on the INP/IPR chemical composition.

Mixing effects on geothermometric calculations of the Newdale geothermal area in the Eastern Snake River Plain, Idaho

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ghanashayam Neupane; Earl D. Mattson; Travis L. McLing

The Newdale geothermal area in Madison and Fremont Counties in Idaho is a known geothermal resource area whose thermal anomaly is expressed by high thermal gradients and numerous wells producing warm water (up to 51 °C). Geologically, the Newdale geothermal area is located within the Eastern Snake River Plain (ESRP) that has a time-transgressive history of sustained volcanic activities associated with the passage of Yellowstone Hotspot from the southwestern part of Idaho to its current position underneath Yellowstone National Park in Wyoming. Locally, the Newdale geothermal area is located within an area that was subjected to several overlapping and nestedmore » caldera complexes. The Tertiary caldera forming volcanic activities and associated rocks have been buried underneath Quaternary flood basalts and felsic volcanic rocks. Two southeast dipping young faults (Teton dam fault and an unnamed fault) in the area provide the structural control for this localized thermal anomaly zone. Geochemically, water samples from numerous wells in the area can be divided into two broad groups – Na-HCO3 and Ca-(Mg)-HCO3 type waters and are considered to be the product of water-rhyolite and water-basalt interactions, respectively. Each type of water can further be subdivided into two groups depending on their degree of mixing with other water types or interaction with other rocks. For example, some bivariate plots indicate that some Ca-(Mg)-HCO3 water samples have interacted only with basalts whereas some samples of this water type also show limited interaction with rhyolite or mixing with Na-HCO3 type water. Traditional geothermometers [e.g., silica variants, Na-K-Ca (Mg-corrected)] indicate lower temperatures for this area; however, a traditional silica-enthalpy mixing model results in higher reservoir temperatures. We applied a new multicomponent equilibrium geothermometry tool (e.g., Reservoir Temperature Estimator, RTEst) that is based on inverse geochemical modeling which explicitly accounts for boiling, mixing, and CO2 degassing. RTEst modeling results indicate that the well water samples are mixed with up to 75% of the near surface groundwater. Relatively, Ca-(Mg)-HCO3 type water samples are more diluted than the Na-HCO3 type water samples. However, both water types result in similar reservoir temperatures, up to 150 °C. Samples in the vicinity of faults produced higher reservoir temperatures than samples away from the faults. Although both the silica-enthalpy mixing and RTEst models indicated promising geothermal reservoir temperatures, evaluation of the subsurface permeability and extent of the thermal anomaly is needed to define the hydrothermal potential of the Newdale geothermal resource.« less

Payments and quality of care in private for-profit and public hospitals in Greece.

PubMed

Kondilis, Elias; Gavana, Magda; Giannakopoulos, Stathis; Smyrnakis, Emmanouil; Dombros, Nikolaos; Benos, Alexis

2011-09-23

Empirical evidence on how ownership type affects the quality and cost of medical care is growing, and debate on these topics is ongoing. Despite the fact that the private sector is a major provider of hospital services in Greece, little comparative information on private versus public sector hospitals is available. The aim of the present study was to describe and compare the operation and performance of private for-profit (PFP) and public hospitals in Greece, focusing on differences in nurse staffing rates, average lengths of stay (ALoS), and Social Health Insurance (SHI) payments for hospital care per patient discharged. Five different datasets were prepared and analyzed, two of which were derived from information provided by the National Statistical Service (NSS) of Greece and the other three from data held by the three largest SHI schemes in the country. All data referred to the 3-year period from 2001 to 2003. PFP hospitals in Greece are smaller than public hospitals, with lower patient occupancy, and have lower staffing rates of all types of nurses and highly qualified nurses compared with public hospitals. Calculation of ALoS using NSS data yielded mixed results, whereas calculations of ALoS and SHI payments using SHI data gave results clearly favoring the public hospital sector in terms of cost-efficiency; in all years examined, over all specialties and all SHI schemes included in our study, unweighted ALoS and SHI payments for hospital care per discharge were higher for PFP facilities. In a mixed healthcare system, such as that in Greece, significant performance differences were observed between PFP and public hospitals. Close monitoring of healthcare provision by hospital ownership type will be essential to permit evidence-based decisions on the future of the public/private mix in terms of healthcare provision.

Ambient Pressure XPS Study of Mixed Conducting Perovskite-Type SOFC Cathode and Anode Materials under Well-Defined Electrochemical Polarization

PubMed Central

2015-01-01

The oxygen exchange activity of mixed conducting oxide surfaces has been widely investigated, but a detailed understanding of the corresponding reaction mechanisms and the rate-limiting steps is largely still missing. Combined in situ investigation of electrochemically polarized model electrode surfaces under realistic temperature and pressure conditions by near-ambient pressure (NAP) XPS and impedance spectroscopy enables very surface-sensitive chemical analysis and may detect species that are involved in the rate-limiting step. In the present study, acceptor-doped perovskite-type La0.6Sr0.4CoO3-δ (LSC), La0.6Sr0.4FeO3-δ (LSF), and SrTi0.7Fe0.3O3-δ (STF) thin film model electrodes were investigated under well-defined electrochemical polarization as cathodes in oxidizing (O2) and as anodes in reducing (H2/H2O) atmospheres. In oxidizing atmosphere all materials exhibit additional surface species of strontium and oxygen. The polaron-type electronic conduction mechanism of LSF and STF and the metal-like mechanism of LSC are reflected by distinct differences in the valence band spectra. Switching between oxidizing and reducing atmosphere as well as electrochemical polarization cause reversible shifts in the measured binding energy. This can be correlated to a Fermi level shift due to variations in the chemical potential of oxygen. Changes of oxidation states were detected on Fe, which appears as FeIII in oxidizing atmosphere and as mixed FeII/III in H2/H2O. Cathodic polarization in reducing atmosphere leads to the reversible formation of a catalytically active Fe0 phase. PMID:26877827

Retention prediction of highly polar ionizable solutes under gradient conditions on a mixed-mode reversed-phase and weak anion-exchange stationary phase.

PubMed

Balkatzopoulou, P; Fasoula, S; Gika, H; Nikitas, P; Pappa-Louisi, A

2015-05-29

In the present work the retention of three highly polar and ionizable solutes - uric acid, nicotinic acid and ascorbic acid - was investigated on a mixed-mode reversed-phase and weak anion-exchange (RP/WAX) stationary phase in buffered aqueous acetonitrile (ACN) mobile phases. A U-shaped retention behavior was observed for all solutes with respect to the eluent organic modifier content studied in a range of 5-95% (v/v). This retention behavior clearly demonstrates the presence of a HILIC-type retention mechanism at ACN-rich hydro-organic eluents and an RP-like retention at aqueous-rich hydro-organic eluents. Hence, this column should be promising for application under both RP and HILIC gradient elution modes. For this reason, a series of programmed elution runs were carried out with increasing (RP) and decreasing (HILIC) organic solvent concentration in the mobile phase. This dual gradient process was successfully modeled by two retention models exhibiting a quadratic or a cubic dependence of the logarithm of the solute retention factor (lnk) upon the organic modifier volume fraction (φ). It was found that both models produced by gradient retention data allow the prediction of solute retention times for both types of programmed elution on the mixed-mode column. Four, in the case of the quadratic model, or five, in the case of the cubic model, initial HILIC- and RP-type gradient runs gave satisfactory retention predictions of any similar kind elution program, even with different flow rate, with an overall error of only 2.5 or 1.7%, respectively. Copyright © 2015 Elsevier B.V. All rights reserved.

Comprehensive evaluation of the long-term performance of rubberized pavement, phase I : laboratory study of rubberized asphalt mix performance.

DOT National Transportation Integrated Search

2012-12-01

Crumb rubber, made from scrap tires, has been introduced into the production of different types of hot : mix asphalt (HMA) in either a wet or dry process. In the wet process, the crumb rubber and binder are : completely mixed to form asphalt rubber (...

Rayleigh-Taylor mixing with space-dependent acceleration

NASA Astrophysics Data System (ADS)

Abarzhi, Snezhana

2016-11-01

We extend the momentum model to describe Rayleigh-Taylor (RT) mixing driven by a space-dependent acceleration. The acceleration is a power-law function of space coordinate, similarly to astrophysical and plasma fusion applications. In RT flow the dynamics of a fluid parcel is driven by a balance per unit mass of the rates of momentum gain and loss. We find analytical solutions in the cases of balanced and imbalanced gains and losses, and identify their dependence on the acceleration exponent. The existence is shown of two typical sub-regimes of self-similar RT mixing - the acceleration-driven Rayleigh-Taylor-type mixing and dissipation-driven Richtymer-Meshkov-type mixing with the latter being in general non-universal. Possible scenarios are proposed for transitions from the balanced dynamics to the imbalanced self-similar dynamics. Scaling and correlations properties of RT mixing are studied on the basis of dimensional analysis. Departures are outlined of RT dynamics with space-dependent acceleration from canonical cases of homogeneous turbulence as well as blast waves with first and second kind self-similarity. The work is supported by the US National Science Foundation.

Effects of organic silicon compounds as additives on charge-discharge cycling efficiencies of lithium in nonaqueous electrolytes for rechargeable lithium cells

NASA Astrophysics Data System (ADS)

Yanagisawa, Ryota; Endo, Hisayuki; Unno, Masafumi; Morimoto, Hideyuki; Tobishima, Shin-ichi

2014-11-01

Influence of mixing organic silicon compounds into 1 M (M: mol L-1) LiPF6-ethylene carbonate (EC)/ethylmethyl carbonate (EMC) (mixing volume ratio = 3:7) mixed solvent electrolytes on charge-discharge cycling efficiencies of lithium metal negative electrodes is examined. As organic silicon compounds, polyether-modified siloxanes with polyethylene oxide chains, chlorotrimethylsilane, tetraethoxysilane, cis-tetra [isobutyl (dimethylsiloxy)] cyclotetrasiloxane and cage-type silsesquioxane are investigated. Charge-discharge cycling tests of lithium are galvanostatically carried out using stainless steel working electrodes. Charge-discharge cycling efficiencies of lithium tend to improve by mixing organic silicon compounds. A cage-type silsesquioxane, octaphenyloctasilsesquioxane (Ph8T8) exhibits the highest cycling efficiency of approximately 80% with small mixing amount of 0.02 M Ph8T8. Mechanism of enhancement of lithium cycling efficiencies by mixing organic silicon compounds is considered to be due to the suppression of excess reduction of LiPF6-EC/EMC by lithium and the growth of surface film on lithium.

How old is old in allegations of age discrimination? The limitations of existing law.

PubMed

Wiener, Richard L; Farnum, Katlyn S

2016-10-01

Under Title VII, courts may give a mixed motive instruction allowing jurors to determine that defendants are liable for discrimination if an illegal factor (here: race, color, religion, sex, or national origin) contributed to an adverse decision. Recently, the Supreme Court held that to conclude that an employer discriminated against a worker because of age, the Age Discrimination in Employment Act, unlike Title VII of the Civil Rights Act of 1964, requires "but for" causality, necessitating jurors to find that age was the determinative factor in an employer's adverse decision regarding that worker. Using a national online sample (N = 392) and 2 study phases, 1 to measure stereotypes, and a second to present experimental manipulations, this study tested whether older worker stereotypes as measured through the lens of the Stereotype Content Model, instruction type (but for vs. mixed motive causality), and plaintiff age influenced mock juror verdicts in an age discrimination case. Decision modeling in Phase 2 with 3 levels of case orientation (i.e., proplaintiff, prodefendant, and neutral) showed that participants relied on multiple factors when making a decision, as opposed to just 1, suggesting that mock jurors favor a mixed model approach to discrimination verdict decisions. In line with previous research, instruction effects showed that mock jurors found in favor of plaintiffs under mixed motive instructions but not under "but for" instructions especially for older plaintiffs (64- and 74-year-old as opposed to 44- and 54-year-old-plaintiffs). Most importantly, in accordance with the Stereotype Content Model theory, competence and warmth stereotypes moderated the instruction effects found for specific judgments. The results of this study show the importance of the type of legal causality required for age discrimination cases. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

A survey of orthodontists' perspectives on the timing of treatment: A pilot study.

PubMed

Al-Shayea, Eman I

2014-10-01

This study aimed to outline orthodontists' perspectives at what stage they would initiate orthodontic treatment and also sought to assess the relationship between orthodontists' views and their genders, types of practice, and experience levels. A questionnaire was sent electronically to 165 practicing orthodontists at different regions in Saudi Arabia. The orthodontists were asked to consider at what stage they would initiate orthodontic treatment for a child with one of 29 different types of occlusal deviations, functional problems, and temporomandibular disorders (TMDs) listed in the questionnaire as their main orthodontic problem. Frequency distributions of all the variables were derived, and comparisons were made using the Chi-square tests. Fifty-two electronically completed questionnaires were returned (31.5% response rate). The majority of the respondents were males (63.5%). The majority of respondents (90%) reported that they would treat most of the occlusal deviations in the mixed dentition stage. Anterior cross-bite was the most frequent indication for treatment during the early mixed dentition stage (73.7%). Conditions rated as best treated during the late mixed, or the permanent dentition stages were; overjet > 6 mm with interdental spacing, maxillary midline diastema >2 mm and deep bite >5 mm without palatal impingement. The majority of respondents (86.6%) preferred to treat most of the functional problems in the deciduous or early mixed dentition stage. Orthodontists with more than 15 years of experience preferred to treat patients with TMDs, whereas those with <15 years of experience opted to refer such patients to TMD specialists. The findings of the present study suggest that orthodontists should consider many factors, such as the risks, benefits, duration, and costs of early and late intervention, when deciding the best timing to begin orthodontic treatment.

A survey of orthodontists’ perspectives on the timing of treatment: A pilot study

PubMed Central

Al-Shayea, Eman I

2014-01-01

Objectives: This study aimed to outline orthodontists’ perspectives at what stage they would initiate orthodontic treatment and also sought to assess the relationship between orthodontists’ views and their genders, types of practice, and experience levels. Materials and Methods: A questionnaire was sent electronically to 165 practicing orthodontists at different regions in Saudi Arabia. The orthodontists were asked to consider at what stage they would initiate orthodontic treatment for a child with one of 29 different types of occlusal deviations, functional problems, and temporomandibular disorders (TMDs) listed in the questionnaire as their main orthodontic problem. Frequency distributions of all the variables were derived, and comparisons were made using the Chi-square tests. Results: Fifty-two electronically completed questionnaires were returned (31.5% response rate). The majority of the respondents were males (63.5%). The majority of respondents (90%) reported that they would treat most of the occlusal deviations in the mixed dentition stage. Anterior cross-bite was the most frequent indication for treatment during the early mixed dentition stage (73.7%). Conditions rated as best treated during the late mixed, or the permanent dentition stages were; overjet > 6 mm with interdental spacing, maxillary midline diastema >2 mm and deep bite >5 mm without palatal impingement. The majority of respondents (86.6%) preferred to treat most of the functional problems in the deciduous or early mixed dentition stage. Orthodontists with more than 15 years of experience preferred to treat patients with TMDs, whereas those with <15 years of experience opted to refer such patients to TMD specialists. Conclusions: The findings of the present study suggest that orthodontists should consider many factors, such as the risks, benefits, duration, and costs of early and late intervention, when deciding the best timing to begin orthodontic treatment. PMID:25426455

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Min Ho; Rhyee, Jong-Soo, E-mail: jsrhyee@khu.ac.kr

We investigated the thermoelectric properties of PbTe/Ag{sub 2}Te bulk composites, synthesized by hand milling, mixing, and hot press sintering. From x-ray diffraction and energy dispersive x-ray spectroscopy measurements, we observed Ag{sub 2}Te phase separation in the PbTe matrix without Ag atom diffusion. In comparison with previously reported pseudo-binary (PbTe){sub 1−x}(Ag{sub 2}Te){sub x} composites, synthesized by high temperature phase separation, the PbTe/Ag{sub 2}Te bulk composites fabricated with a low temperature phase mixing process give rise to p-type conduction of carriers with significantly decreased electrical conductivity. This indicates that Ag atom diffusion in the PbTe matrix changes the sign of the Seebeckmore » coefficient to n-type and also increases the carrier concentration. Effective p-type doping with low temperature phase separation by mixing and hot press sintering can enhance the thermoelectric performance of PbTe/Ag{sub 2}Te bulk composites, which can be used as a p-type counterpart of n-type (PbTe){sub 1−x}(Ag{sub 2}Te){sub x} bulk composites.« less

Resource recycling technique of abandoned TNT-RDX-AL mixed explosive

NASA Astrophysics Data System (ADS)

Chen, Siyang; Ding, Yukui

2017-08-01

TNT-RDX-AL mixed explosive is a kind of high energy mixed explosive. It has the detonation characteristics even when reaching the scrapping standard. Inappropriate disposal often causes serious accident. Employing the resource recycling technique, the abandoned TNT-RDX-AL mixed explosive can be recycled. This paper summarized the progress of recycling of abandoned mixed explosive. What's more, three kinds of technological process of resource recycling abandoned TNT-RDX-AL mixed explosives are introduced. The author analysis of the current recovery processes and provided a reference for the recycling of the other same type explosive.

Does the presence and mix of destinations influence walking and physical activity?

PubMed

King, Tania Louise; Bentley, Rebecca Jodie; Thornton, Lukar Ezra; Kavanagh, Anne Marie

2015-09-17

Local destinations have previously been shown to be associated with higher levels of both physical activity and walking, but little is known about how specific destinations are related to activity. This study examined associations between types and mix of destinations and both walking frequency and physical activity. The sample consisted of 2349 residents of 50 urban areas in metropolitan Melbourne, Australia. Using geographic information systems, seven types of destinations were examined within three network buffers (400 meters (m), 800 m and 1200 m) of respondents' homes. Multilevel logistic regression was used to estimate effects of each destination type separately, as well as destination mix (variety) on: 1) likelihood of walking for at least 10 min ≥ 4/week; 2) likelihood of being sufficiently physically active. All models were adjusted for potential confounders. All destination types were positively associated with walking frequency, and physical activity sufficiency at 1200 m. For the 800 m buffer: all destinations except transport stops and sports facilities were significantly associated with physical activity, while all except sports facilities were associated with walking frequency; at 400 m, café/takeaway food stores and transport stops were associated with walking frequency and physical activity sufficiency, and sports facilities were also associated with walking frequency. Strongest associations for both outcomes were observed for community resources and small food stores at both 800 m and 1200 m. For all buffer distances: greater mix was associated with greater walking frequency. Inclusion of walking in physical activity models led to attenuation of associations. The results of this analysis indicate that there is an association between destinations and both walking frequency and physical activity sufficiency, and that this relationship varies by destination type. It is also clear that greater mix of destinations positively predicts walking frequency and physical activity sufficiency.

Decrease of postprandial endothelial dysfunction by spice mix added to high-fat hamburger meat in men with Type 2 diabetes mellitus.

PubMed

Li, Z; Henning, S M; Zhang, Y; Rahnama, N; Zerlin, A; Thames, G; Tseng, C H; Heber, D

2013-05-01

Consumption of a high-fat diet has been demonstrated to promote endothelial dysfunction, possibly through an increase in lipid peroxidation and decrease in serum nitric oxide. The present study was designed to investigate whether consumption of a hamburger cooked with a polyphenol-rich spice mixture will reduce postprandial lipid oxidation and endothelial dysfunction in men with Type 2 diabetes. Twenty-two subjects consumed burgers cooked with salt only (control burger) or with salt and spice mix (spice burger) in randomized order. The postprandial concentration of urinary malondialdehyde and nitrate/nitrite as well as the peripheral arterial tonometry score were determined. Eighteen subjects completed the study. Postprandial serum glucose, insulin and triglyceride concentrations were similar in all subjects after control burger or spice burger consumption. Urine malondialdehyde excretion in mmol/g creatinine was reduced by 31% (P < 0.001) after consuming the spice burger compared with the control burger. Two hours after consumption of the burgers, the peripheral arterial tonometry score was significantly different between control burger consumption (-9.7 ± 21.5%) and spice burger consumption (+18.0 ± 42.4%) (P = 0.025). Mean urinary nitrate/nitrite concentrations in urine collected during the 6 h after consumption of the control burger was 9.09 ± 5.7 mmol/g creatinine, but 12.37 ± 7.00 mmol/g creatinine after the spice burger (P = 0.053). Adding a spice mix to hamburger meat prior to cooking resulted in a reduction in urinary malondialdehyde, an increase in urinary nitrate/nitrite and improvement of postprandial endothelial dysfunction in men with Type 2 diabetes. Therefore, cooking a hamburger with a polyphenol-rich spice mixture may lead to potential cardiovascular benefits in patients with Type 2 diabetes mellitus. © 2013 The Authors. Diabetic Medicine © 2013 Diabetes UK.

Adenocarcinoma with BAC Features Presented as the Nonsolid Nodule Is Prone to Be False-Negative on 18F-FDG PET/CT

PubMed Central

Wu, Hu-bing; Wang, Lijuan; Wang, Quan-shi; Han, Yan-jian; Li, Hong-sheng; Zhou, Wen-lan; Tian, Ying

2015-01-01

Purpose. The present study investigated which type of adenocarcinoma with BAC features was prone to be false-negative on 18F-FDG PET/CT. Materials and Methods. A retrospective study was performed on 51 consecutive patients with localized adenocarcinoma with BAC features. CT and PET were assessed for lesion size, GGO percentage, and SUVmax. Lesions with FDG uptake the same as or more than mediastinal blood-pool activity were considered as PET-positive. Results. Of the 51 cases, 19.6% presented as pure GGO nodules, 31.4% as mixed nodules, and 49.0% as solid nodules. None of the pure GGO nodules was 18F-FDG avid, compared with 37.5% of mixed nodules and 96.0% of solid nodules (χ 2 = 31.55, P = 0.000). In the mixed nodule group, SUVmax was negatively correlated with GGO percentage (r = −0.588; P = 0.021). The positive detection rate of 18F-FDG PET/CT was 50.0%, 55.6%, and 100% in tumors 1.1–2.0 cm, 2.1–3.0 cm, and >3.0 cm in diameter, respectively (χ 2 = 5.815, P = 0.055). General linear model factor analysis showed that the GGO was an important factor contributing to false-negative PET/CT results (F = 23.992, P = 0.000), but lesion size was not (F = 0.602, P = 0.866). Conclusions. The present study indicated that the adenocarcinoma with BAC features presented as nonsolid nodule is prone to be false negative on 18F-FDG PET/CT. PMID:25879020