Sample records for model date acquired

  1. 45 CFR 34.3 - Filing procedures and time limits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... not limited to type, design, model number, date acquired, value when acquired, value when lost, and... insured, insurance information, such as insurance carrier, type of coverage, deductible, and whether claim... the date of the incident. (2) If the claim accrues in the time of war or in the time of armed conflict...

  2. Association between Hypoalbuminaemia and Mortality in Patients with Community-Acquired Bacteraemia Is Primarily Related to Acute Disorders

    PubMed Central

    Magnussen, Bjarne; Oren Gradel, Kim; Gorm Jensen, Thøger; Kolmos, Hans Jørn; Pedersen, Court; Just Vinholt, Pernille; Touborg Lassen, Annmarie

    2016-01-01

    We sought to investigate whether hypoalbuminaemia was mainly caused by acute or chronic factors in patients with community-acquired bacteraemia. In this population-based study, we considered 1844 adult cases of community-acquired bacteraemia that occurred in Funen, Denmark between 2000 and 2008. We used a stepwise prognostic predisposition-insult-response-organ dysfunction (PIRO) logistic regression model by initially including age and comorbidity, then added bacterial species, and finally sepsis severity. The models were furthermore analysed using receiver operating characteristic (ROC) curves. Outcomes comprised mortality incidence on days 0–30 and 31–365 after the bacteraemia episode. Each step was performed with and without baseline albumin level measured on the date of bacteraemia. In 422 patients, their latest albumin measurement taken 8–30 days before the date of bacteraemia was also used in the analysis together with the baseline albumin level. For each decrease of 1g/L in plasma albumin level, the odds ratios (95% confidence intervals) of mortality in the period of 0–30 days after bacteraemia were 0.86 (0.84–0.88) in both predisposition (P) and predisposition-insult (PI) models and 0.87 (0.85–0.89) in the full PIRO-model. The AUC values were 0.78 and 0.66 for mortality in the period of 0–30 days in the model comprising only predisposition factors with and without albumin levels added as a factor, respectively. The AUC values in the full PIRO-model were 0.81 and 0.73 with and without consideration of albumin levels, respectively. A higher proportion of patients died within 30 days if there was a decrease in the albumin level between days 8 and 30 before bacteraemia and the actual bacteraemia date. A single plasma albumin measurement on the bacteraemia date was a better prognostic predictor of short-term mortality than the sepsis severity score. PMID:27611431

  3. Animal models of middle ear cholesteatoma.

    PubMed

    Yamamoto-Fukuda, Tomomi; Takahashi, Haruo; Koji, Takehiko

    2011-01-01

    Middle ear acquired cholesteatoma is a pathological condition associated with otitis media, which may be associated with temporal bone resorption, otorrhea and hearing loss, and occasionally various other complications. Cholesteatoma is characterized by the enhanced proliferation of epithelial cells with aberrant morphologic characteristics. Unfortunately, our understanding of the mechanism underlying its pathogenesis is limited. To investigate its pathogenesis, different animal models have been used. This paper provides a brief overview of the current status of research in the field of pathogenesis of middle ear acquired cholesteatoma, four types of animal models previously reported on, up-to-date cholesteatoma research using these animal models, our current studies of the local hybrid ear model, and the future prospect of new animal models of middle ear cholesteatoma.

  4. Animal Models of Middle Ear Cholesteatoma

    PubMed Central

    Yamamoto-Fukuda, Tomomi; Takahashi, Haruo; Koji, Takehiko

    2011-01-01

    Middle ear acquired cholesteatoma is a pathological condition associated with otitis media, which may be associated with temporal bone resorption, otorrhea and hearing loss, and occasionally various other complications. Cholesteatoma is characterized by the enhanced proliferation of epithelial cells with aberrant morphologic characteristics. Unfortunately, our understanding of the mechanism underlying its pathogenesis is limited. To investigate its pathogenesis, different animal models have been used. This paper provides a brief overview of the current status of research in the field of pathogenesis of middle ear acquired cholesteatoma, four types of animal models previously reported on, up-to-date cholesteatoma research using these animal models, our current studies of the local hybrid ear model, and the future prospect of new animal models of middle ear cholesteatoma. PMID:21541229

  5. [3-dimensional models of actual or simulated cesarean sections].

    PubMed

    Patzak, B; Schaller, A

    2001-01-01

    Following upon an etymological and historical introduction, this report refers to two three-dimensional wax models of Caesarean sections, which have recently been acquired by the Pathological-anatomical Federal Museum in Vienna. Information is given on origin, dating and kind of production; questions of indication and operation technique, and--when in doubt--obduction technique, are being considered.

  6. 27 CFR 478.125a - Personal firearms collection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... importer Model Serial No. Type Caliber or gauge Disposition Date Name and address (business address if... firearm was transferred from the business inventory into the personal collection or otherwise acquired as... receipt of the firearm into the business inventory or other acquisition, (3) The licensee recorded the...

  7. Meteorological models for estimating phenology of corn

    NASA Technical Reports Server (NTRS)

    Daughtry, C. S. T.; Cochran, J. C.; Hollinger, S. E.

    1984-01-01

    Knowledge of when critical crop stages occur and how the environment affects them should provide useful information for crop management decisions and crop production models. Two sources of data were evaluated for predicting dates of silking and physiological maturity of corn (Zea mays L.). Initial evaluations were conducted using data of an adapted corn hybrid grown on a Typic Agriaquoll at the Purdue University Agronomy Farm. The second phase extended the analyses to large areas using data acquired by the Statistical Reporting Service of USDA for crop reporting districts (CRD) in Indiana and Iowa. Several thermal models were compared to calendar days for predicting dates of silking and physiological maturity. Mixed models which used a combination of thermal units to predict silking and days after silking to predict physiological maturity were also evaluated. At the Agronomy Farm the models were calibrated and tested on the same data. The thermal models were significantly less biased and more accurate than calendar days for predicting dates of silking. Differences among the thermal models were small. Significant improvements in both bias and accuracy were observed when the mixed models were used to predict dates of physiological maturity. The results indicate that statistical data for CRD can be used to evaluate models developed at agricultural experiment stations.

  8. Mass Balance of Multiyear Sea Ice in the Southern Beaufort Sea

    DTIC Science & Technology

    2013-09-30

    model of MY ice circulation, which is shown in Figure 1. In this model , we consider the Beaufort Sea to consist of four zones defined by mean drift...Arctic Regional Climate Model Simulation Project 3 International Arctic Buoy Program 4 Sea ice Experiment - Dynamic Nature of the Arctic 5Cold...2 Table 2: Datasets compiled to date Geophysical data type Source Time period acquired Buoy tracks IABP 12 hrly position data 1978-2012 Ice

  9. Teachers' Personal and Team Empowerment and their Relations to Organizational Outcomes: Contradictory or Compatible Constructs?

    ERIC Educational Resources Information Center

    Somech, Anit

    2005-01-01

    To date most models of empowerment have focused on teachers' personal empowerment, which is defined as intrinsic task motivation reflecting an employee's orientation to his or her work role. Interestingly, little scholarly attention has been turned to the interaction of empowerment and work-team membership, that is, to empowerment acquired from…

  10. Status of the KTH-NASA Wind-Tunnel Test for Acquisition of Transonic Nonlinear Aeroelastic Data

    NASA Technical Reports Server (NTRS)

    Silva, Walter A.; Ringertz, Ulf; Stenfelt, Gloria; Eller, David; Keller, Donald F.; Chwalowski, Pawel

    2016-01-01

    This paper presents a status report on the collaboration between the Royal Institute of Technology (KTH) in Sweden and the NASA Langley Research Center regarding the design, fabrication, modeling, and testing of a full-span lighter configuration in the Transonic Dynamics Tunnel (TDT). The goal of the test is to acquire transonic limit-cycle- oscillation (LCO) data, including accelerations, strains, and unsteady pressures. Finite element models (FEMs) and aerodynamic models are presented and discussed along with results obtained to date.

  11. The Earth Microbiome Project and modeling the planets microbial potential (Invited)

    NASA Astrophysics Data System (ADS)

    Gilbert, J. A.

    2013-12-01

    The understanding of Earth's climate and ecology requires multiscale observations of the biosphere, of which microbial life are a major component. However, to acquire and process physical samples of soil, water and air that comprise the appropriate spatial and temporal resolution to capture the immense variation in microbial dynamics, would require a herculean effort and immense financial resources dwarfing even the most ambitious projects to date. To overcome this hurdle we created the Earth Microbiome Project, a crowd-sourced effort to acquire physical samples from researchers around the world that are, importantly, contextualized with physical, chemical and biological data detailing the environmental properties of that sample in the location and time it was acquired. The EMP leverages these existing efforts to target a systematic analysis of microbial taxonomic and functional dynamics across a vast array of environmental parameter gradients. The EMP captures the environmental gradients, location, time and sampling protocol information about every sample donated by our valued collaborators. Physical samples are then processed using a standardized DNA extraction, PCR, and shotgun sequencing protocol to generate comparable data regarding the microbial community structure and function in each sample. To date we have processed >17,000 samples from 40 different biomes. One of the key goals of the EMP is to map the spatiotemporal variability of microbial communities to capture the changes in important functional processes that need to be appropriately expressed in models to provide reliable forecasts of ecosystem phenotype across our changing planet. This is essential if we are to develop economically sound strategies to be good stewards of our Earth. The EMP recognizes that environments are comprised of complex sets of interdependent parameters and that the development of useful predictive computational models of both terrestrial and atmospheric systems requires recognition and accommodation of sources of uncertainty.

  12. Developing Remote Sensing Capabilities for Meter-Scale Sea Ice Properties

    DTIC Science & Technology

    2013-09-30

    such as MODIS . APPROACH 1. Task and acquire high resolution panchromatic and multispectral optical (e.g. Quickbird, Worldview, National Assets...does not display a currently valid OMB control number. 1. REPORT DATE 30 SEP 2013 2. REPORT TYPE 3. DATES COVERED 00-00-2013 to 00-00-2013 4...cloud cover , an excessive percentage of the imagery acquired over drifting sites was cloud covered , and the vendor did not delay acquisitions or

  13. An initial model for estimating soybean development stages from spectral data

    NASA Technical Reports Server (NTRS)

    Henderson, K. E.; Badhwar, G. D.

    1982-01-01

    A model, utilizing a direct relationship between remotely sensed spectral data and soybean development stage, has been proposed. The model is based upon transforming the spectral data in Landsat bands to greenness values over time and relating the area of this curve to soybean development stage. Soybean development stages were estimated from data acquired in 1978 from research plots at the Purdue University Agronomy Farm as well as Landsat data acquired over sample areas of the U.S. Corn Belt in 1978 and 1979. Analysis of spectral data from research plots revealed that the model works well with reasonable variation in planting date, row spacing, and soil background. The R-squared of calculated U.S. observed development stage exceeded 0.91 for all treatment variables. Using Landsat data the calculated U.S. observed development stage gave an R-squared of 0.89 in 1978 and 0.87 in 1979. No difference in the models performance could be detected between early and late planted fields, small and large fields, or high and low yielding fields.

  14. BIM and IoT: A Synopsis from GIS Perspective

    NASA Astrophysics Data System (ADS)

    Isikdag, U.

    2015-10-01

    Internet-of-Things (IoT) focuses on enabling communication between all devices, things that are existent in real life or that are virtual. Building Information Models (BIMs) and Building Information Modelling is a hype that has been the buzzword of the construction industry for last 15 years. BIMs emerged as a result of a push by the software companies, to tackle the problems of inefficient information exchange between different software and to enable true interoperability. In BIM approach most up-to-date an accurate models of a building are stored in shared central databases during the design and the construction of a project and at post-construction stages. GIS based city monitoring / city management applications require the fusion of information acquired from multiple resources, BIMs, City Models and Sensors. This paper focuses on providing a method for facilitating the GIS based fusion of information residing in digital building "Models" and information acquired from the city objects i.e. "Things". Once this information fusion is accomplished, many fields ranging from Emergency Response, Urban Surveillance, Urban Monitoring to Smart Buildings will have potential benefits.

  15. 77 FR 38734 - Defense Federal Acquisition Regulation Supplement; Acquisition of Tents and Other Temporary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... Structures (DFARS Case 2012-D015) AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD... structures. DATES: Effective date: June 29, 2012. Comment date: Comments are due by August 28, 2012..., when acquiring tents and other temporary structures, regardless of whether purchased by DoD or by...

  16. Multispectral airborne imagery in the field reveals genetic determinisms of morphological and transpiration traits of an apple tree hybrid population in response to water deficit

    PubMed Central

    Virlet, Nicolas; Costes, Evelyne; Martinez, Sébastien; Kelner, Jean-Jacques; Regnard, Jean-Luc

    2015-01-01

    Genetic studies of response to water deficit in adult trees are limited by low throughput of the usual phenotyping methods in the field. Here, we aimed at overcoming this bottleneck, applying a new methodology using airborne multispectral imagery and in planta measurements to compare a high number of individuals. An apple tree population, grafted on the same rootstock, was submitted to contrasting summer water regimes over two years. Aerial images acquired in visible, near- and thermal-infrared at three dates each year allowed calculation of vegetation and water stress indices. Tree vigour and fruit production were also assessed. Linear mixed models were built accounting for date and year effects on several variables and including the differential response of genotypes between control and drought conditions. Broad-sense heritability of most variables was high and 18 quantitative trait loci (QTLs) independent of the dates were detected on nine linkage groups of the consensus apple genetic map. For vegetation and stress indices, QTLs were related to the means, the intra-crown heterogeneity, and differences induced by water regimes. Most QTLs explained 15−20% of variance. Airborne multispectral imaging proved relevant to acquire simultaneous information on a whole tree population and to decipher genetic determinisms involved in response to water deficit. PMID:26208644

  17. A project in two parts: Developing fire histories for the eastern U.S. and creating a climate-based continental fire frequency model to fill data gaps

    Treesearch

    Richard Guyette; Michael Stambaugh; Daniel Dey

    2011-01-01

    Tree-ring dated fire scars provide long-term records of fire frequency, giving land managers valuable baseline information about the fire regimes that existed prior to Euro-American settlement. However, for the East, fire history data prove difficult to acquire because the generally moister climate of the region causes rapid decay of wood. In an endeavor to fill data...

  18. A model for HIV/AIDS pandemic with optimal control

    NASA Astrophysics Data System (ADS)

    Sule, Amiru; Abdullah, Farah Aini

    2015-05-01

    Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is pandemic. It has affected nearly 60 million people since the detection of the disease in 1981 to date. In this paper basic deterministic HIV/AIDS model with mass action incidence function are developed. Stability analysis is carried out. And the disease free equilibrium of the basic model was found to be locally asymptotically stable whenever the threshold parameter (RO) value is less than one, and unstable otherwise. The model is extended by introducing two optimal control strategies namely, CD4 counts and treatment for the infective using optimal control theory. Numerical simulation was carried out in order to illustrate the analytic results.

  19. 48 CFR 39.106 - Year 2000 compliance.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.106 Year 2000 compliance. When acquiring information technology that will be required to perform date/time processing involving dates... information technology to be Year 2000 compliant; or (2) Require that non-compliant information technology be...

  20. 78 FR 10266 - Proposed Information Collection (Veterans Application for Assistance in Acquiring Special Housing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... (Veterans Application for Assistance in Acquiring Special Housing Adaptations) Activity: Comment Request.../or adaptations to their current resident. DATES: Written comments and recommendations on the proposed... Special Housing Adaptations, VA Form 26-4555d. OMB Control Number: 2900-0300. Type of Review: Revision of...

  1. 75 FR 15494 - Proposed Information Collection (Veterans Application for Assistance in Acquiring Special Housing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... (Veterans Application for Assistance in Acquiring Special Housing Adaptations) Activity: Comment Request... adaptations to their current resident. DATES: Written comments and recommendations on the proposed collection... Special Housing Adaptations, VA Form 26-4555d. OMB Control Number: 2900-0300. Type of Review: Extension of...

  2. 76 FR 63354 - Proposed Information Collection (Application in Acquiring Specially Adapted Housing or Special...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... (Application in Acquiring Specially Adapted Housing or Special Home Adaptation Grant) Activity: Comment Request... or special home adaptation grant. DATES: Written comments and recommendations on the proposed... Housing or Special Home Adaptation Grant, VA Form 26-4555. OMB Control Number: 2900-0132. Type of Review...

  3. 76 FR 78085 - Permissible Investments for Federal and State Savings Associations: Corporate Debt Securities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-15

    ... Part 362 Permissible Investments for Federal and State Savings Associations: Corporate Debt Securities... association from acquiring and retaining a corporate debt security unless it determines, prior to acquiring... whether a corporate debt security is eligible for investment under this proposed rule. DATES: Comments...

  4. 76 FR 49539 - Proposed Collection; Comment Request for Forms 3921 and 3922

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... 3921 and 3922 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for comments... Acquired Through an Employee Stock Purchase Plan Under Section 423(c). DATES: Written comments should be... Section 422(b). Form 3922, Transfer of Stock Acquired Through an Employee Stock Purchase Plan Under...

  5. Acquired Dyslexia in a Turkish-English Speaker

    ERIC Educational Resources Information Center

    Raman, Ilhan; Weekes, Brendan S.

    2005-01-01

    The Turkish script is characterised by completely transparent bidirectional mappings between orthography and phonology. To date, there has been no reported evidence of acquired dyslexia in Turkish speakers leading to the naive view that reading and writing problems in Turkish are probably rare. We examined the extent to which phonological…

  6. ISS Plasma Environment: Status of CCMC Products for ISS Mission Ops

    NASA Technical Reports Server (NTRS)

    Minow, Joseph

    2010-01-01

    ISS Program currently using FPMU Ne, Te in-situ measurements to support operations and anomaly investigations. Working to acquire alternative data sources if FPMU is not available. Work is progressing on CCMC tools for low Earth orbit ionosphere characterization. Validation against FPMU data required before model output can be used for ISS operational support. MSFC plans to continue comparing CTIP output during FPMU campaigns. Results to date have been useful in identifying ionospheric origins of high latitude charging environments.

  7. Development and Validation of a New Methodology to Assess the Vineyard Water Status by On-the-Go Near Infrared Spectroscopy

    PubMed Central

    Diago, Maria P.; Fernández-Novales, Juan; Gutiérrez, Salvador; Marañón, Miguel; Tardaguila, Javier

    2018-01-01

    Assessing water status and optimizing irrigation is of utmost importance in most winegrowing countries, as the grapevine vegetative growth, yield, and grape quality can be impaired under certain water stress situations. Conventional plant-based methods for water status monitoring are either destructive or time and labor demanding, therefore unsuited to detect the spatial variation of moisten content within a vineyard plot. In this context, this work aims at the development and comprehensive validation of a novel, non-destructive methodology to assess the vineyard water status distribution using on-the-go, contactless, near infrared (NIR) spectroscopy. Likewise, plant water status prediction models were built and intensely validated using the stem water potential (ψs) as gold standard. Predictive models were developed making use of a vast number of measurements, acquired on 15 dates with diverse environmental conditions, at two different spatial scales, on both sides of vertical shoot positioned canopies, over two consecutive seasons. Different cross-validation strategies were also tested and compared. Predictive models built from east-acquired spectra yielded the best performance indicators in both seasons, with determination coefficient of prediction (RP2) ranging from 0.68 to 0.85, and sensitivity (expressed as prediction root mean square error) between 0.131 and 0.190 MPa, regardless the spatial scale. These predictive models were implemented to map the spatial variability of the vineyard water status at two different dates, and provided useful, practical information to help delineating specific irrigation schedules. The performance and the large amount of data that this on-the-go spectral solution provides, facilitates the exploitation of this non-destructive technology to monitor and map the vineyard water status variability with high spatial and temporal resolution, in the context of precision and sustainable viticulture. PMID:29441086

  8. Development and Validation of a New Methodology to Assess the Vineyard Water Status by On-the-Go Near Infrared Spectroscopy.

    PubMed

    Diago, Maria P; Fernández-Novales, Juan; Gutiérrez, Salvador; Marañón, Miguel; Tardaguila, Javier

    2018-01-01

    Assessing water status and optimizing irrigation is of utmost importance in most winegrowing countries, as the grapevine vegetative growth, yield, and grape quality can be impaired under certain water stress situations. Conventional plant-based methods for water status monitoring are either destructive or time and labor demanding, therefore unsuited to detect the spatial variation of moisten content within a vineyard plot. In this context, this work aims at the development and comprehensive validation of a novel, non-destructive methodology to assess the vineyard water status distribution using on-the-go, contactless, near infrared (NIR) spectroscopy. Likewise, plant water status prediction models were built and intensely validated using the stem water potential (ψ s ) as gold standard. Predictive models were developed making use of a vast number of measurements, acquired on 15 dates with diverse environmental conditions, at two different spatial scales, on both sides of vertical shoot positioned canopies, over two consecutive seasons. Different cross-validation strategies were also tested and compared. Predictive models built from east-acquired spectra yielded the best performance indicators in both seasons, with determination coefficient of prediction ([Formula: see text]) ranging from 0.68 to 0.85, and sensitivity (expressed as prediction root mean square error) between 0.131 and 0.190 MPa, regardless the spatial scale. These predictive models were implemented to map the spatial variability of the vineyard water status at two different dates, and provided useful, practical information to help delineating specific irrigation schedules. The performance and the large amount of data that this on-the-go spectral solution provides, facilitates the exploitation of this non-destructive technology to monitor and map the vineyard water status variability with high spatial and temporal resolution, in the context of precision and sustainable viticulture.

  9. Improvement of web-based data acquisition and management system for GOSAT validation lidar data analysis

    NASA Astrophysics Data System (ADS)

    Okumura, Hiroshi; Takubo, Shoichiro; Kawasaki, Takeru; Abdullah, Indra Nugraha; Uchino, Osamu; Morino, Isamu; Yokota, Tatsuya; Nagai, Tomohiro; Sakai, Tetsu; Maki, Takashi; Arai, Kohei

    2013-01-01

    A web-base data acquisition and management system for GOSAT (Greenhouse gases Observation SATellite) validation lidar data-analysis has been developed. The system consists of data acquisition sub-system (DAS) and data management sub-system (DMS). DAS written in Perl language acquires AMeDAS (Automated Meteorological Data Acquisition System) ground-level local meteorological data, GPS Radiosonde upper-air meteorological data, ground-level oxidant data, skyradiometer data, skyview camera images, meteorological satellite IR image data and GOSAT validation lidar data. DMS written in PHP language demonstrates satellite-pass date and all acquired data. In this article, we briefly describe some improvement for higher performance and higher data usability. GPS Radiosonde upper-air meteorological data and U.S. standard atmospheric model in DAS automatically calculate molecule number density profiles. Predicted ozone density prole images above Saga city are also calculated by using Meteorological Research Institute (MRI) chemistry-climate model version 2 for comparison to actual ozone DIAL data.

  10. 77 FR 1019 - Renewable Energy Alternate Uses of Existing Facilities on the Outer Continental Shelf-Acquire a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ...-0045] RIN 1010-AD79 Renewable Energy Alternate Uses of Existing Facilities on the Outer Continental... rule related to acquiring a lease non-competitively for offshore renewable energy projects. DATES... or Timothy Redding, Renewable Energy, BOEM, at (703) 787-1219 or email [email protected

  11. 46 CFR Appendix II to Part 390 - Sample Capital Construction Fund Agreement

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) In the case of a vessel constructed or acquired within one year of final delivery from the shipyard... date of such vessel's final delivery; (2) In the case of a vessel reconstructed or acquired more than one year after final delivery from the shipyard after construction with the aid of qualified...

  12. 46 CFR Appendix II to Part 390 - Sample Capital Construction Fund Agreement

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) In the case of a vessel constructed or acquired within one year of final delivery from the shipyard... date of such vessel's final delivery; (2) In the case of a vessel reconstructed or acquired more than one year after final delivery from the shipyard after construction with the aid of qualified...

  13. 7 CFR 985.152 - Handling report.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) date of acquisition; (e) date when oil was produced; (f) net weight of oil in the lot; (g) quantity of that class of oil in the producer's annual allotment available for handler before this acquisition; and... Allotment Certificate, showing that the acquired oil was within the unused portion of the producer's annual...

  14. 7 CFR 985.152 - Handling report.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) date of acquisition; (e) date when oil was produced; (f) net weight of oil in the lot; (g) quantity of that class of oil in the producer's annual allotment available for handler before this acquisition; and... Allotment Certificate, showing that the acquired oil was within the unused portion of the producer's annual...

  15. 7 CFR 985.152 - Handling report.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) date of acquisition; (e) date when oil was produced; (f) net weight of oil in the lot; (g) quantity of that class of oil in the producer's annual allotment available for handler before this acquisition; and... Allotment Certificate, showing that the acquired oil was within the unused portion of the producer's annual...

  16. 7 CFR 985.152 - Handling report.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) date of acquisition; (e) date when oil was produced; (f) net weight of oil in the lot; (g) quantity of that class of oil in the producer's annual allotment available for handler before this acquisition; and... Allotment Certificate, showing that the acquired oil was within the unused portion of the producer's annual...

  17. 36 CFR 223.193 - Procedures for reporting acquisition and disposition of unprocessed Federal timber.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; the origin of National Forest System timber acquired; the sale name; the contract number(s); brand... conveyed to another person; and the date of disposal; (2) An accounting by origin, in net board feet...) The volume by species of National Forest System surplus species timber acquired and exported or sold...

  18. Landsat non-US standard catalog

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Non-U.S. Standard Catalog lists Non-U.S. imagery acquired by Landsat 1 and 2 which was processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found are also given.

  19. 29 CFR 95.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to make the property usable for the purpose for which it was acquired. Other charges, such as the... required work of the award have been completed by the recipient and DOL. (h) Commercial organization means... project or program costs not borne by DOL. (k) Date of completion means the date on which all work under...

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ryan Hruska

    Currently, small Unmanned Aerial Vehicles (UAVs) are primarily used for capturing and down-linking real-time video. To date, their role as a low-cost airborne platform for capturing high-resolution, georeferenced still imagery has not been fully utilized. On-going work within the Unmanned Vehicle Systems Program at the Idaho National Laboratory (INL) is attempting to exploit this small UAV-acquired, still imagery potential. Initially, a UAV-based still imagery work flow model was developed that includes initial UAV mission planning, sensor selection, UAV/sensor integration, and imagery collection, processing, and analysis. Components to support each stage of the work flow are also being developed. Critical tomore » use of acquired still imagery is the ability to detect changes between images of the same area over time. To enhance the analysts’ change detection ability, a UAV-specific, GIS-based change detection system called SADI or System for Analyzing Differences in Imagery is under development. This paper will discuss the associated challenges and approaches to collecting still imagery with small UAVs. Additionally, specific components of the developed work flow system will be described and graphically illustrated using varied examples of small UAV-acquired still imagery.« less

  1. Integration of remote sensing and geographic information systems for Great Lakes water quality monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lathrop, R.G. Jr.

    1988-01-01

    The utility of three operational satellite remote sensing systems, namely, the Landsat Thematic Mapper (TM), the SPOT High Resolution Visible (HRV) sensors and the NOAA Advanced Very High Resolution Radiometer (AVHRR), were evaluated as a means of estimating water quality and surface temperature. Empirical calibration through linear regression techniques was used to relate near-simultaneously acquired satellite radiance/reflectance data and water quality observations obtained in Green Bay and the nearshore waters of Lake Michigan. Four dates of TM and one date each of SPOT and AVHRR imagery/surface reference data were acquired and analyzed. Highly significant relationships were identified between the TMmore » and SPOT data and secchi disk depth, nephelometric turbidity, chlorophyll a, total suspended solids (TSS), absorbance, and surface temperature (TM only). The AVHRR data were not analyzed independently but were used for comparison with the TM data. Calibrated water quality image maps were input to a PC-based raster GIS package, EPPL7. Pattern interpretation and spatial analysis techniques were used to document the circulation dynamics and model mixing processes in Green Bay. A GIS facilitates the retrieval, query and spatial analysis of mapped information and provides the framework for an integrated operational monitoring system for the Great Lakes.« less

  2. A prototype for automation of land-cover products from Landsat Surface Reflectance Data Records

    NASA Astrophysics Data System (ADS)

    Rover, J.; Goldhaber, M. B.; Steinwand, D.; Nelson, K.; Coan, M.; Wylie, B. K.; Dahal, D.; Wika, S.; Quenzer, R.

    2014-12-01

    Landsat data records of surface reflectance provide a three-decade history of land surface processes. Due to the vast number of these archived records, development of innovative approaches for automated data mining and information retrieval were necessary. Recently, we created a prototype utilizing open source software libraries for automatically generating annual Anderson Level 1 land cover maps and information products from data acquired by the Landsat Mission for the years 1984 to 2013. The automated prototype was applied to two target areas in northwestern and east-central North Dakota, USA. The approach required the National Land Cover Database (NLCD) and two user-input target acquisition year-days. The Landsat archive was mined for scenes acquired within a 100-day window surrounding these target dates, and then cloud-free pixels where chosen closest to the specified target acquisition dates. The selected pixels were then composited before completing an unsupervised classification using the NLCD. Pixels unchanged in pairs of the NLCD were used for training decision tree models in an iterative process refined with model confidence measures. The decision tree models were applied to the Landsat composites to generate a yearly land cover map and related information products. Results for the target areas captured changes associated with the recent expansion of oil shale production and agriculture driven by economics and policy, such as the increase in biofuel production and reduction in Conservation Reserve Program. Changes in agriculture, grasslands, and surface water reflect the local hydrological conditions that occurred during the 29-year span. Future enhancements considered for this prototype include a web-based client, ancillary spatial datasets, trends and clustering algorithms, and the forecasting of future land cover.

  3. Annotated bibliography of structural equation modelling: technical work.

    PubMed

    Austin, J T; Wolfle, L M

    1991-05-01

    Researchers must be familiar with a variety of source literature to facilitate the informed use of structural equation modelling. Knowledge can be acquired through the study of an expanding literature found in a diverse set of publishing forums. We propose that structural equation modelling publications can be roughly classified into two groups: (a) technical and (b) substantive applications. Technical materials focus on the procedures rather than substantive conclusions derived from applications. The focus of this article is the former category; included are foundational/major contributions, minor contributions, critical and evaluative reviews, integrations, simulations and computer applications, precursor and historical material, and pedagogical textbooks. After a brief introduction, we annotate 294 articles in the technical category dating back to Sewall Wright (1921).

  4. LANDSAT US standard catalog, 1-31 March 1976

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The U.S. Standard Catalog lists U.S. imagery acquired by LANDSAT 1 and LANDSAT 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  5. LANDSAT: Non-US standard catalog. [LANDSAT imagery for August 1977

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The non-U. S. Standard Catalog lists non-U. S. imagery acquired by LANDSAT 1 and 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  6. LANDSAT non-US standard catalog, 1-31 May 1976

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The non-U.S. standard catalog lists non-U.S. imagery acquired by LANDSAT 1 and LANDSAT 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  7. LANDSAT 2 cumulative US standard catalog. [LANDSAT imagery for January 1976

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The U.S. Standard Catalog lists U.S. imagery acquired by LANDSAT 1 and LANDSAT 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality, are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  8. LANDSAT: US standard catalog, 1 January 1977 through 31 January 1977

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The U.S. Standard Catalog lists U.S. imagery acquired by LANDSAT 1 and LANDSAT 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  9. 77 FR 73089 - Cambria Investment Management, L.P. and Cambria ETF Trust; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... Investing Fund's Advisory Group will not control (individually or in the aggregate) a Fund within the... group of investment companies as the series to acquire Shares. DATES: Filing Dates: The application was... Fund will (a) be advised by Cambria or an entity controlling, controlled by, or under common control...

  10. Combining Crop Model and Remote Sensing Data at High Resolution for the Assessment of Rice Agricultural Practices in the South-Eastern France (Take 5 Experiment SPOT4-SPOT5)

    NASA Astrophysics Data System (ADS)

    Courault, D.; Ruget, F.; Talab-ou-Ali, H.; Hagolle, O.; Delmotte, S.; Barbier, J. M.; Boschetti, M.; Mouret, J. C.

    2016-08-01

    Crop systems are constantly changing due to modifications in the agricultural practices to respond to market changes, the constraints of the environment, the climate hazards... Rice cultivation practiced in the Camargue region (SE France) have decreased these last years, however rice plays a crucial role for the hydrological balance of the region and for crop systems desalinizing soils. The aim of this study is to analyze the potentialities of remote sensing data acquired at high spatial and temporal resolution (HRST) to identify the main agricultural practices and estimate their impact on rice production. A large dataset acquired over the Camargue from the Take5 experiment (SPOT4 in 2013 and SPOT5 in 2015), completed by Landsat data has been used. Two assimilation methods of HRST data were evaluated within a crop model. Results showed the impact of the spatial variability of practices on the yields. The sowing dates were retrieved from inverse procedures and gave satisfactory results compared to ground surveys.

  11. LANDSAT US standard catalog, 1-30 September 1977. [LANDSAT imagery for September, 1977

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The U. S. Standard Catalog lists U. S. imagery acquired by LANDSAT 1 and 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover, and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  12. LANDSAT Non-US standard catalog, 1-31 December 1975. [LANDSAT imagery for December 1975

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Non-U.S. Standard Catalog lists Non-U.S. imagery acquired by LANDSAT 1 and 2 which has been processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  13. Information Technology Management: DoD Organization Information Assurance Management of Information Technology Goods and Services Acquired Through Interagency Agreements

    DTIC Science & Technology

    2006-02-23

    Information Technology Management Department of Defense Office of Inspector General February 23, 2006 AccountabilityIntegrityQuality DoD...Organization Information Assurance Management of Information Technology Goods and Services Acquired Through Interagency Agreements (D-2006-052) Report...REPORT TYPE 3. DATES COVERED 00-00-2006 to 00-00-2006 4. TITLE AND SUBTITLE Information Technology Management: DoD Organization Information

  14. LANDSAT non-U.S. standard catalog, 1 January 1977 through 31 January 1977. [LANDSAT imagery January 1977

    NASA Technical Reports Server (NTRS)

    1977-01-01

    The Non-U.S. Standard Catalog lists Non-U.S. imagery acquired by LANDSAT 1 and LANDSAT 2 which was processed and input to the data files during the referenced month. Data, such as date acquired, cloud cover, and image quality are given for each scene. The microfilm roll and frame on which the scene may be found is also given.

  15. Health Care: Franchise Business Activity Contracts for Medical Services

    DTIC Science & Technology

    2003-06-30

    Health Care Department of Defense Office of the Inspector General June 30, 2003 AccountabilityIntegrityQuality Franchise Business Activity Contracts...control number. 1. REPORT DATE 30 JUN 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Health Care: Franchise Business...services should be interested in the issue of acquiring medical services through the Department of the Treasury, Franchise Business Activity contracts. 15

  16. Factors Leading to Effectiveness and Satisfaction in Civil Engineer Information Systems

    DTIC Science & Technology

    2008-03-01

    recently acquired MySQL in 2008 shortly after Oracle failed to acquire MySQL in 2007. For more information on policy implications concerning the use...individual level serves as the pertinent outcome variable and is used to evaluate and compare information systems in this study. Researchers have found...interim work information management system used by the Civil Engineer Operations Flight. The functions served by this system date back to the late

  17. The Earth's magnetic field in Italy during the Neolithic period: New data from the Early Neolithic site of Portonovo (Marche, Italy)

    NASA Astrophysics Data System (ADS)

    Tema, Evdokia; Ferrara, Enzo; Camps, Pierre; Conati Barbaro, Cecilia; Spatafora, Simone; Carvallo, Claire; Poidras, Thierry

    2016-08-01

    We present new, full geomagnetic field vector results from three Neolithic ovens discovered at the archaeological site of Portonovo (Marche, Italy). The discovered structures are a rare example of very well preserved underground ovens from the Early Neolithic period. Standard thermal demagnetization procedures were used to isolate the direction of the Characteristic Remanent Magnetization acquired by the baked clay during the ovens' last firing. The corresponding archaeointensities were determined by the multi-specimen procedure (MSP-DSC) and show a clear intensity low during the Neolithic period. Both directional and intensity results are of high quality, offering the first contribution of full geomagnetic field vector data for this period in Italy. The new data are compared with other contemporaneous data from Europe and with global geomagnetic field models. Independent archaeomagnetic dating of the three ovens was also performed by means of the SCHA.DIF.14k model. The obtained results are in excellent agreement with available radiocarbon dates and confirm that all ovens belong to the Neolithic. These new data importantly enrich our knowledge of the geomagnetic field during the Neolithic period that is poorly documented by data, not only in Italy but also in the whole of Europe and show that archaeomagnetic dating can provide precise results even for prehistoric periods.

  18. 26 CFR 1.897-9T - Treatment of certain interest in publicly traded corporations, definition of foreign person, and...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... fair market value greater than the fair market value on that date of 5 percent of the regularly traded class of the corporation's stock with the lowest fair market value. However, if a non-regularly traded... if on the date it was acquired by its present holder it had a fair market value greater than the fair...

  19. 26 CFR 1.367(b)-3 - Repatriation of foreign corporate assets in certain nonrecognition transactions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of an exchanging shareholder whose stock in the foreign acquired corporation has a fair market value... stock in FC has a fair market value of $48,000 on the date DC1 receives the DC2 stock. (ii) Result. Because DC1's stock in FC has a fair market value of less than $50,000 on the date of the section 367(b...

  20. Relevance of ERTS-1 to the state of Ohio

    NASA Technical Reports Server (NTRS)

    Sweet, D. C. (Principal Investigator); Wells, T. L.; Wukelic, G. E.

    1973-01-01

    The author has identified the following significant results. To date, only one significant result has been reported for the Ohio ERTS program. This result relates to the proven usefulness of ERTS-1 imagery for mapping and inventorying strip-mined areas in southeastern Ohio. ERTS provides a tool for rapidly and economically acquiring an up-to-date inventory of strip-mined lands for state planning purposes which was not previously possible.

  1. 7 CFR 987.24 - Nomination and selection.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... locations of his date gardens, voting in the nominations for producer members and producer alternate members... through April which he produced in his own gardens or acquired from other producers. The individual...

  2. 7 CFR 987.24 - Nomination and selection.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... locations of his date gardens, voting in the nominations for producer members and producer alternate members... through April which he produced in his own gardens or acquired from other producers. The individual...

  3. 7 CFR 987.24 - Nomination and selection.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... locations of his date gardens, voting in the nominations for producer members and producer alternate members... through April which he produced in his own gardens or acquired from other producers. The individual...

  4. 7 CFR 987.24 - Nomination and selection.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... locations of his date gardens, voting in the nominations for producer members and producer alternate members... through April which he produced in his own gardens or acquired from other producers. The individual...

  5. 7 CFR 987.24 - Nomination and selection.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... locations of his date gardens, voting in the nominations for producer members and producer alternate members... through April which he produced in his own gardens or acquired from other producers. The individual...

  6. 75 FR 30040 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ... Committee: Microbiology, Infectious Diseases and AIDS Initial Review Group; Acquired Immunodeficiency..., Microbiology and Infectious Diseases Research, National Institutes of Health, HHS) Dated: May 24, 2010...

  7. 25 CFR 700.205 - Eligibility requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... be the date used for determination of the amount of the assistance payment. (c) Time of payment... dwelling and vacation of the acquired habitation and/or improvement, if any, in the area partitioned to the...

  8. 25 CFR 700.205 - Eligibility requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... be the date used for determination of the amount of the assistance payment. (c) Time of payment... dwelling and vacation of the acquired habitation and/or improvement, if any, in the area partitioned to the...

  9. Standardisation of crown-rump length measurement.

    PubMed

    Ioannou, C; Sarris, I; Hoch, L; Salomon, L J; Papageorghiou, A T

    2013-09-01

    Correct estimation of gestational age is essential for any study of ultrasound biometry and for everyday clinical practice. However, inconsistency in pregnancy dating may occur through differences in measurement methods or errors during measurement. In the INTERGROWTH-21(st) Project, pregnancies are dated by the last menstrual period, provided that it is certain and associated with a regular menstrual cycle, and the gestational age by dates concurs with a first-trimester ultrasound crown-rump length (CRL) estimation. Hence, there was a need to standardise CRL measurement methodology across the study sites in this international, multicentre project to avoid systematic differences in dating. To achieve uniformity we undertook the following steps: the ultrasound technique was standardised by disseminating an illustrated, operating manual describing CRL plane landmarks and calliper application, and posters describing the correct acquisition technique were disseminated for quick reference. To ensure that all ultrasonographers understood the methodology, they forwarded a log-book to the INTERGROWTH-21(st) Ultrasound Coordinating Unit, containing the answers to a written test on the manual material and five images of a correctly acquired CRL. Interpretation of CRL was also standardised by ensuring that the same CRL regression formula was used across all study sites. These methods should minimise potential systematic errors in dating associated with pooling data from different health institutions, and represent a model for standardising CRL measurement in future studies. © 2013 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2013 RCOG.

  10. 26 CFR 1.381(c)(1)-2 - Net operating loss carryovers; two or more dates of distribution or transfer in the taxable year.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Acquiring corporation X Transferor corporation Y Transferor corporation Z 1954 xxx xxx ($30,000) 1955 xxx xxx 1,000 1956 xxx xxx 1,000 1957 ($20,000) ($25,000) 1,000 Ending 6-30-58 xxx 1,000 xxx Ending 9-30-58 xxx xxx 1,000 1958 36,500 xxx xxx The sequence in which the losses of the acquiring corporation...

  11. 26 CFR 1.381(c)(1)-2 - Net operating loss carryovers; two or more dates of distribution or transfer in the taxable year.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Acquiring corporation X Transferor corporation Y Transferor corporation Z 1954 xxx xxx ($30,000) 1955 xxx xxx 1,000 1956 xxx xxx 1,000 1957 ($20,000) ($25,000) 1,000 Ending 6-30-58 xxx 1,000 xxx Ending 9-30-58 xxx xxx 1,000 1958 36,500 xxx xxx The sequence in which the losses of the acquiring corporation...

  12. Space Acquisitions: Development and Oversight Challenges in Delivering Improved Space Situational Awareness Capabilities

    DTIC Science & Technology

    2011-05-01

    information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and...OMB control number. 1 . REPORT DATE MAY 2011 2. REPORT TYPE 3. DATES COVERED 00-00-2011 to 00-00-2011 4. TITLE AND SUBTITLE Space...space operations depend. GAO was asked to ( 1 ) review key systems being planned and acquired to provide SSA, and their progress meeting cost

  13. 76 FR 27999 - Pacific Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... Essential Fish Habitat Review Committee (EFHRC) that is open to the public. DATES: The conference call will... plan for acquiring data and information pertinent to a review of groundfish essential fish habitat, to...

  14. Evidence for terrigenic SF6 in groundwater from basaltic aquifers, Jeju Island, Korea: Implications for groundwater dating

    USGS Publications Warehouse

    Koh, Dong-Chan; Plummer, Niel; Busenberg, Eurybiades; Kim, Yongje

    2007-01-01

    Measurements of the concentrations of dichlorodifluoromethane (CFC-12), tritium (3H), and sulfur hexafluoride (SF6) in groundwater from basaltic aquifers in Jeju Island, Korea, demonstrate a terrigenic source of SF6. Using a lumped-parameter dispersion model, groundwater was identified as young water (<15 years), old water with negligible CFC-12 and 3H, and binary mixtures of the two. Model calculations using dispersion models and binary mixing based on 3H and CFC-12 concentrations demonstrate a non-atmospheric excess of SF6 relative to CFC-12 and 3H concentrations for more than half of the samples. The non-atmospheric excess SF6 may have originated from terrigenic sources in relict volcanic fluids, which could have acquired SF6 from granites and basement rocks of the island during volcanic activity. Local excess anthropogenic sources of SF6 are unlikely. The SF6 age is biased young relative to the CFC-12 age, typically up to 20 years and as high as 30 years. This age bias is more pronounced in samples of groundwater older than 15 years. The presence of terrigenic SF6 can affect the entire dating range for groundwater in mixtures that contain a fraction of old water.

  15. Effects of Pharmacokinetic Processes and Varied Dosing Schedules on the Dynamics of Acquired Resistance to Erlotinib in EGFR-Mutant Lung Cancer

    PubMed Central

    Foo, Jasmine; Chmielecki, Juliann; Pao, William; Michor, Franziska

    2013-01-01

    Introduction Erlotinib (Tarceva) is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, which effectively targets EGFR-mutant driven non–small-cell lung cancer. However, the evolution of acquired resistance because of a second-site mutation (T790M) within EGFR remains an obstacle to successful treatment. Methods We used mathematical modeling and available clinical trial data to predict how different pharmacokinetic parameters (fast versus slow metabolism) and dosing schedules (low dose versus high dose; missed doses with and without make-up doses) might affect the evolution of T790M-mediated resistance in mixed populations of tumor cells. Results We found that high-dose pulses with low-dose continuous therapy impede the development of resistance to the maximum extent, both pre- and post-emergence of resistance. The probability of resistance is greater in fast versus slow drug metabolizers, suggesting a potential mechanism, unappreciated to date, influencing acquired resistance in patients. In case of required dose modifications because of toxicity, little difference is observed in terms of efficacy and resistance dynamics between the standard daily dose (150 mg/d) and 150 mg/d alternating with 100 mg/d. Missed doses are expected to lead to resistance faster, even if make-up doses are attempted. Conclusions For existing and new kinase inhibitors, this novel framework can be used to rationally and rapidly design optimal dosing strategies to minimize the development of acquired resistance. PMID:22982659

  16. Utility of ERTS for monitoring the breeding habitat of migratory waterfowl

    NASA Technical Reports Server (NTRS)

    Work, E. A., Jr.; Gilmer, D. S.; Klett, A. T.

    1974-01-01

    Since 1968 the Bureau of Sport Fisheries and Wildlife (BSF&W) and the Environmental Research Institute of Michigan have cooperated on developing applications of remote sensing to the management of migratory waterfowl. Basically, this work has been concerned with (1) the assimilation of data on surface water conditions so that the data can be used as an index of annual waterfowl production, and (2) the collection of data on land use and wetland quality so that a measure of habitat carrying capacity is obtained. To date, efforts have been directed toward utilizing ERTS to monitor surface water conditions. An example of a model used for predicting the annual production of mallards (Anas platyrhynchos) is presented. The data inputs to this model and the potential for acquiring these data using ERTS are described.

  17. Crossflow Instability on a Wedge-Cone at Mach 3.5

    NASA Technical Reports Server (NTRS)

    Beeler, George B.; Wilkinson, Stephen P.; Balakumar, P.; McDaniel, Keith S.

    2012-01-01

    As a follow-on activity to the HyBoLT flight experiment, a six degree half angle wedge-cone model at zero angle of attack has been employed to experimentally and computationally study the boundary layer crossflow instability at Mach 3.5 under low disturbance freestream conditions. Computed meanflow and linear stability analysis results are presented along with corresponding experimental Pitot probe data. Using a model-mounted probe survey apparatus, data acquired to date show a well defined stationary crossflow vortex pattern on the flat wedge surface. This effort paves the way for additional detailed, calibrated flow field measurements of the crossflow instability, both stationary and traveling modes, and transition-to-turbulence under quiet flow conditions as a means of validating existing stability theory and providing a foundation for dynamic flight instrumentation development.

  18. Evaluating Dense 3d Reconstruction Software Packages for Oblique Monitoring of Crop Canopy Surface

    NASA Astrophysics Data System (ADS)

    Brocks, S.; Bareth, G.

    2016-06-01

    Crop Surface Models (CSMs) are 2.5D raster surfaces representing absolute plant canopy height. Using multiple CMSs generated from data acquired at multiple time steps, a crop surface monitoring is enabled. This makes it possible to monitor crop growth over time and can be used for monitoring in-field crop growth variability which is useful in the context of high-throughput phenotyping. This study aims to evaluate several software packages for dense 3D reconstruction from multiple overlapping RGB images on field and plot-scale. A summer barley field experiment located at the Campus Klein-Altendorf of University of Bonn was observed by acquiring stereo images from an oblique angle using consumer-grade smart cameras. Two such cameras were mounted at an elevation of 10 m and acquired images for a period of two months during the growing period of 2014. The field experiment consisted of nine barley cultivars that were cultivated in multiple repetitions and nitrogen treatments. Manual plant height measurements were carried out at four dates during the observation period. The software packages Agisoft PhotoScan, VisualSfM with CMVS/PMVS2 and SURE are investigated. The point clouds are georeferenced through a set of ground control points. Where adequate results are reached, a statistical analysis is performed.

  19. Assessment of Unmanned Aerial Vehicles Imagery for Quantitative Monitoring of Wheat Crop in Small Plots

    PubMed Central

    Lelong, Camille C. D.; Burger, Philippe; Jubelin, Guillaume; Roux, Bruno; Labbé, Sylvain; Baret, Frédéric

    2008-01-01

    This paper outlines how light Unmanned Aerial Vehicles (UAV) can be used in remote sensing for precision farming. It focuses on the combination of simple digital photographic cameras with spectral filters, designed to provide multispectral images in the visible and near-infrared domains. In 2005, these instruments were fitted to powered glider and parachute, and flown at six dates staggered over the crop season. We monitored ten varieties of wheat, grown in trial micro-plots in the South-West of France. For each date, we acquired multiple views in four spectral bands corresponding to blue, green, red, and near-infrared. We then performed accurate corrections of image vignetting, geometric distortions, and radiometric bidirectional effects. Afterwards, we derived for each experimental micro-plot several vegetation indexes relevant for vegetation analyses. Finally, we sought relationships between these indexes and field-measured biophysical parameters, both generic and date-specific. Therefore, we established a robust and stable generic relationship between, in one hand, leaf area index and NDVI and, in the other hand, nitrogen uptake and GNDVI. Due to a high amount of noise in the data, it was not possible to obtain a more accurate model for each date independently. A validation protocol showed that we could expect a precision level of 15% in the biophysical parameters estimation while using these relationships. PMID:27879893

  20. Earliest Archaeological Evidence of Persistent Hominin Carnivory

    PubMed Central

    Ferraro, Joseph V.; Plummer, Thomas W.; Pobiner, Briana L.; Oliver, James S.; Bishop, Laura C.; Braun, David R.; Ditchfield, Peter W.; Seaman, John W.; Binetti, Katie M.; Seaman, John W.; Hertel, Fritz; Potts, Richard

    2013-01-01

    The emergence of lithic technology by ∼2.6 million years ago (Ma) is often interpreted as a correlate of increasingly recurrent hominin acquisition and consumption of animal remains. Associated faunal evidence, however, is poorly preserved prior to ∼1.8 Ma, limiting our understanding of early archaeological (Oldowan) hominin carnivory. Here, we detail three large well-preserved zooarchaeological assemblages from Kanjera South, Kenya. The assemblages date to ∼2.0 Ma, pre-dating all previously published archaeofaunas of appreciable size. At Kanjera, there is clear evidence that Oldowan hominins acquired and processed numerous, relatively complete, small ungulate carcasses. Moreover, they had at least occasional access to the fleshed remains of larger, wildebeest-sized animals. The overall record of hominin activities is consistent through the stratified sequence – spanning hundreds to thousands of years – and provides the earliest archaeological evidence of sustained hominin involvement with fleshed animal remains (i.e., persistent carnivory), a foraging adaptation central to many models of hominin evolution. PMID:23637995

  1. Circadian Phase Resetting via Single and Multiple Control Targets

    PubMed Central

    Bagheri, Neda; Stelling, Jörg; Doyle, Francis J.

    2008-01-01

    Circadian entrainment is necessary for rhythmic physiological functions to be appropriately timed over the 24-hour day. Disruption of circadian rhythms has been associated with sleep and neuro-behavioral impairments as well as cancer. To date, light is widely accepted to be the most powerful circadian synchronizer, motivating its use as a key control input for phase resetting. Through sensitivity analysis, we identify additional control targets whose individual and simultaneous manipulation (via a model predictive control algorithm) out-perform the open-loop light-based phase recovery dynamics by nearly 3-fold. We further demonstrate the robustness of phase resetting by synchronizing short- and long-period mutant phenotypes to the 24-hour environment; the control algorithm is robust in the presence of model mismatch. These studies prove the efficacy and immediate application of model predictive control in experimental studies and medicine. In particular, maintaining proper circadian regulation may significantly decrease the chance of acquiring chronic illness. PMID:18795146

  2. Automated Error Detection in Physiotherapy Training.

    PubMed

    Jovanović, Marko; Seiffarth, Johannes; Kutafina, Ekaterina; Jonas, Stephan M

    2018-01-01

    Manual skills teaching, such as physiotherapy education, requires immediate teacher feedback for the students during the learning process, which to date can only be performed by expert trainers. A machine-learning system trained only on correct performances to classify and score performed movements, to identify sources of errors in the movement and give feedback to the learner. We acquire IMU and sEMG sensor data from a commercial-grade wearable device and construct an HMM-based model for gesture classification, scoring and feedback giving. We evaluate the model on publicly available and self-generated data of an exemplary movement pattern executions. The model achieves an overall accuracy of 90.71% on the public dataset and 98.9% on our dataset. An AUC of 0.99 for the ROC of the scoring method could be achieved to discriminate between correct and untrained incorrect executions. The proposed system demonstrated its suitability for scoring and feedback in manual skills training.

  3. 75 FR 65312 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ...: Request for Reauthorization and Extension of Existing Blanket Authorization to Acquire Securities under.... Applicants: Western Electricity Coordinating Council. Description: Notice of Proposed Cancellation of Western Electricity Coordinating Council's Reliability Management System. Filed Date: 10/12/2010. Accession Number...

  4. Modeling of the "PLAN DA MATTUN" Archaeological Site Using a Combination of Different Sensors

    NASA Astrophysics Data System (ADS)

    Novák, D.; Tokarczyk, P.; Theiler, P. W.

    2012-07-01

    Plan da Mattun is located at ~2200 metre above sea level in the Tasna valley in alpine south-eastern Switzerland. In this remote location, finds dating back to the time of Ötzi (3000 B.C.) were discovered by archaeologists from the University of Zurich. For detailed investigations of the site as well as for documentation and visualization purposes the archaeologists were interested in digital models of the terrain and of certain boulders. In the presented project a digital terrain model of the rock stream located at the beginning of the valley was created, as well as detailed models of four larger boulders. These boulders average to 15 metre in height and width. The roughness of terrain makes it difficult to access certain areas and requires using multiple surveying techniques in order to cover all objects of interest. Therefore the digital terrain model was acquired using a combination of terrestrial laser scanning (TLS) and photogrammetric recording from an unmanned aerial vehicle (UAV). The larger boulders were reconstructed with a combination of TLS, terrestrial and UAV-based photogrammetry. With this approach it was possible to acquire a highaccuracy dataset over an area of 0.12 km2 under difficult conditions. The dataset includes a digital terrain model with a ground sampling distance of 10 cm and a relative accuracy of 2 cm in moderately sloped terrain. The larger boulders feature a resolution of 1 cm and a relative accuracy of 0.5 cm. The 3D data is to be used both for archaeological visualization purposes and for geological analysis of the rock stream.

  5. The origin and diversification of eukaryotes: problems with molecular phylogenetics and molecular clock estimation

    PubMed Central

    Roger, Andrew J; Hug, Laura A

    2006-01-01

    Determining the relationships among and divergence times for the major eukaryotic lineages remains one of the most important and controversial outstanding problems in evolutionary biology. The sequencing and phylogenetic analyses of ribosomal RNA (rRNA) genes led to the first nearly comprehensive phylogenies of eukaryotes in the late 1980s, and supported a view where cellular complexity was acquired during the divergence of extant unicellular eukaryote lineages. More recently, however, refinements in analytical methods coupled with the availability of many additional genes for phylogenetic analysis showed that much of the deep structure of early rRNA trees was artefactual. Recent phylogenetic analyses of a multiple genes and the discovery of important molecular and ultrastructural phylogenetic characters have resolved eukaryotic diversity into six major hypothetical groups. Yet relationships among these groups remain poorly understood because of saturation of sequence changes on the billion-year time-scale, possible rapid radiations of major lineages, phylogenetic artefacts and endosymbiotic or lateral gene transfer among eukaryotes. Estimating the divergence dates between the major eukaryote lineages using molecular analyses is even more difficult than phylogenetic estimation. Error in such analyses comes from a myriad of sources including: (i) calibration fossil dates, (ii) the assumed phylogenetic tree, (iii) the nucleotide or amino acid substitution model, (iv) substitution number (branch length) estimates, (v) the model of how rates of evolution change over the tree, (vi) error inherent in the time estimates for a given model and (vii) how multiple gene data are treated. By reanalysing datasets from recently published molecular clock studies, we show that when errors from these various sources are properly accounted for, the confidence intervals on inferred dates can be very large. Furthermore, estimated dates of divergence vary hugely depending on the methods used and their assumptions. Accurate dating of divergence times among the major eukaryote lineages will require a robust tree of eukaryotes, a much richer Proterozoic fossil record of microbial eukaryotes assignable to extant groups for calibration, more sophisticated relaxed molecular clock methods and many more genes sampled from the full diversity of microbial eukaryotes. PMID:16754613

  6. Acquired dyslexia in a Turkish-English speaker.

    PubMed

    Raman, Ilhan; Weekes, Brendan S

    2005-06-01

    The Turkish script is characterised by completely transparent bidirectional mappings between orthography and phonology. To date, there has been no reported evidence of acquired dyslexia in Turkish speakers leading to the naïve view that reading and writing problems in Turkish are probably rare. We examined the extent to which phonological impairment and orthographic transparency influence reading disorders in a native Turkish speaker. BRB is a bilingual Turkish-English speaker with deep dysphasia accompanied by acquired dyslexia in both languages. The main findings are an effect of imageability on reading in Turkish coincident with surface dyslexia in English and preserved nonword reading. BRB's acquired dyslexia suggests that damage to phonological representations might have a consequence for learning to read in Turkish. We argue that BRB's acquired dyslexia has a common locus in chronic underactivation of phonological representations in Turkish and English. Despite a common locus, reading problems manifest themselves differently according to properties of the script and the type of task.

  7. Jack Hills, Australia

    NASA Image and Video Library

    2009-06-02

    This image acquired by NASA Terra spacecraft, shows the oldest material on Earth which has yet been dated by man is a zircon mineral of 4.4 billion years old from a sedimentary gneiss in the Jack Hills of the Narre Gneiss Terrane of Australia.

  8. 76 FR 77054 - Proposed Collection; Comment Request for Regulation Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... information collection requirements related to amortization of intangible property. DATES: Written comments....gov . SUPPLEMENTARY INFORMATION: Title: Amortization of Intangible Property. OMB Number: 1545-1671. Regulation Project Number: (TD 8865). Abstract: These regulations apply to property acquired after January 25...

  9. 77 FR 59647 - Notice of Inventory Completion: California Department of Parks and Recreation, Sacramento, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ... hair. At an unknown date, the remains were acquired by the California Department of Parks and... of the two clusters of hair. The Wounded Knee Massacre was the last major armed conflict between...

  10. 48 CFR 39.002 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY 39.002 Definitions. As used in this part— Modular contracting means use of one or more contracts to acquire information technology systems in successive... technology, means that the information technology accurately processes date/time data (including, but not...

  11. BRITICE-CHRONO: Constraining rates and style of marine-influenced ice sheet decay to provide a data-rich playground for ice sheet modellers

    NASA Astrophysics Data System (ADS)

    Clark, Chris

    2014-05-01

    Uncertainty exists regarding the fate of the Antarctic and Greenland ice sheets and how they will respond to forcings from sea level and atmospheric and ocean temperatures. If we want to know more about the mechanisms and rate of change of shrinking ice sheets, then why not examine an ice sheet that has fully disappeared and track its retreat through time? If achieved in enough detail such information could become a data-rich playground for improving the next breed of numerical ice sheet models to be used in ice and sea level forecasting. We regard that the last British-Irish Ice Sheet is a good target for this work, on account of its small size, density of information and with its numerous researchers already investigating it. BRITICE-CHRONO is a large (>45 researchers) NERC-funded consortium project comprising Quaternary scientists and glaciologists who will search the seafloor around Britain and Ireland and parts of the landmass in order to find and extract samples of sand, rock and organic matter that can be dated (OSL; Cosmogenic; 14C) to reveal the timing and rate of change of the collapsing British-Irish Ice Sheet. The purpose is to produce a high resolution dataset on the demise on an ice sheet - from the continental shelf edge and across the marine to terrestrial transition. Some 800 new date assessments will be added to those that already exist. This poster reports on the hypotheses that underpin the work. Data on retreat will be collected by focusing on 8 transects running from the continental shelf edge to a short distance (10s km) onshore and acquiring marine and terrestrial samples for geochronometric dating. The project includes funding for 587 radiocarbon, 140 OSL and 158 TCN samples for surface exposure dating; with sampling accomplished by two research cruises and 16 fieldwork campaigns. Results will reveal the timing and rate of change of ice margin recession for each transect, and combined with existing landform and dating databases, will be used to build an ice sheet-wide empirical reconstruction of retreat incorporating Bayesian analysis to assess uncertainty. We invite and encourage ice sheet modellers to use our data for modelling experiments and in particular to explore the role of bed topography in modulating ice retreat.

  12. Teaching adaptive leadership to family medicine residents: what? why? how?

    PubMed

    Eubank, Daniel; Geffken, Dominic; Orzano, John; Ricci, Rocco

    2012-09-01

    Health care reform calls for patient-centered medical homes built around whole person care and healing relationships. Efforts to transform primary care practices and deliver these qualities have been challenging. This study describes one Family Medicine residency's efforts to develop an adaptive leadership curriculum and use coaching as a teaching method to address this challenge. We review literature that describes a parallel between the skills underlying such care and those required for adaptive leadership. We address two questions: What is leadership? Why focus on adaptive leadership? We then present a synthesis of leadership theories as a set of process skills that lead to organization learning through effective work relationships and adaptive leadership. Four models of the learning process needed to acquire such skills are explored. Coaching is proposed as a teaching method useful for going beyond information transfer to create the experiential learning necessary to acquire the process skills. Evaluations of our efforts to date are summarized. We discuss key challenges to implementing such a curriculum and propose that teaching adaptive leadership is feasible but difficult in the current medical education and practice contexts.

  13. Building Change Detection in Very High Resolution Satellite Stereo Image Time Series

    NASA Astrophysics Data System (ADS)

    Tian, J.; Qin, R.; Cerra, D.; Reinartz, P.

    2016-06-01

    There is an increasing demand for robust methods on urban sprawl monitoring. The steadily increasing number of high resolution and multi-view sensors allows producing datasets with high temporal and spatial resolution; however, less effort has been dedicated to employ very high resolution (VHR) satellite image time series (SITS) to monitor the changes in buildings with higher accuracy. In addition, these VHR data are often acquired from different sensors. The objective of this research is to propose a robust time-series data analysis method for VHR stereo imagery. Firstly, the spatial-temporal information of the stereo imagery and the Digital Surface Models (DSMs) generated from them are combined, and building probability maps (BPM) are calculated for all acquisition dates. In the second step, an object-based change analysis is performed based on the derivative features of the BPM sets. The change consistence between object-level and pixel-level are checked to remove any outlier pixels. Results are assessed on six pairs of VHR satellite images acquired within a time span of 7 years. The evaluation results have proved the efficiency of the proposed method.

  14. Volcanic activity at Etna volcano, Sicily, Italy between June 2011 and March 2017 studied with TanDEM-X SAR interferometry

    NASA Astrophysics Data System (ADS)

    Kubanek, J.; Raible, B.; Westerhaus, M.; Heck, B.

    2017-12-01

    High-resolution and up-to-date topographic data are of high value in volcanology and can be used in a variety of applications such as volcanic flow modeling or hazard assessment. Furthermore, time-series of topographic data can provide valuable insights into the dynamics of an ongoing eruption. Differencing topographic data acquired at different times enables to derive areal coverage of lava, flow volumes, and lava extrusion rates, the most important parameters during ongoing eruptions for estimating hazard potential, yet most difficult to determine. Anyhow, topographic data acquisition and provision is a challenge. Very often, high-resolution data only exists within a small spatial extension, or the available data is already outdated when the final product is provided. This is especially true for very dynamic landscapes, such as volcanoes. The bistatic TanDEM-X radar satellite mission enables for the first time to generate up-to-date and high-resolution digital elevation models (DEMs) repeatedly using the interferometric phase. The repeated acquisition of TanDEM-X data facilitates the generation of a time-series of DEMs. Differencing DEMs generated from bistatic TanDEM-X data over time can contribute to monitor topographic changes at active volcanoes, and can help to estimate magmatic ascent rates. Here, we use the bistatic TanDEM-X data to investigate the activity of Etna volcano in Sicily, Italy. Etna's activity is characterized by lava fountains and lava flows with ash plumes from four major summit crater areas. Especially the newest crater, the New South East Crater (NSEC) that was formed in 2011 has been highly active in recent years. Over one hundred bistatic TanDEM-X data pairs were acquired between January 2011 and March 2017 in StripMap mode, covering episodes of lava fountaining and lava flow emplacement at Etna's NSEC and its surrounding area. Generating DEMs of every bistatic data pair enables us to assess areal extension of the lava flows, to calculate lava flow volume, and lava extrusion rates. TanDEM-X data have been acquired at Etna during almost every overflight of the TanDEM-X satellite mission, resulting in a high-temporal resolution of DEMs giving highly valuable insights into Etna's volcanic activity of the last six years.

  15. Deficient BIM Expression as a Mechanism of Intrinsic and Acquired Resistance to Targeted Therapies in EGFR-Mutant and ALK-Positive Lung Cancers

    DTIC Science & Technology

    2015-08-01

    AWARD NUMBER: W81XWH-13-1-0226 TITLE: Deficient BIM Expression as a Mechanism of Intrinsic and Acquired Resistance to Targeted Therapies in...REPORT TYPE Annual 3. DATES COVERED 1 Aug 2014 - 31 Jul 2015 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Deficient BIM Expression as a Mechanism of...the time of resistance. We are now using these patient-derived cell lines to assess BIM levels and apoptotic response to next-generation inhibitors

  16. Deficient BIM Expression as a Mechanism of Intrinsic and Acquired Resistance to Targeted Therapies in EGFR-Mutant and ALK-Positive Lung Cancers

    DTIC Science & Technology

    2015-08-01

    AWARD NUMBER: W81XWH-13-1-0227 TITLE: Deficient BIM Expression as a Mechanism of Intrinsic and Acquired Resistance to Targeted Therapies in...TYPE Annual 3. DATES COVERED 1 Aug 2014 - 31 Jul 2015 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Deficient BIM Expression as a Mechanism of Intrinsic...time of resistance. We are now using these patient-derived cell lines to assess BIM levels and apoptotic response to next-generation inhibitors. The

  17. Web-based data acquisition and management system for GOSAT validation Lidar data analysis

    NASA Astrophysics Data System (ADS)

    Okumura, Hiroshi; Takubo, Shoichiro; Kawasaki, Takeru; Abdullah, Indra N.; Uchino, Osamu; Morino, Isamu; Yokota, Tatsuya; Nagai, Tomohiro; Sakai, Tetsu; Maki, Takashi; Arai, Kohei

    2012-11-01

    An web-base data acquisition and management system for GOSAT (Greenhouse gases Observation SATellite) validation lidar data analysis is developed. The system consists of data acquisition sub-system (DAS) and data management sub-system (DMS). DAS written in Perl language acquires AMeDAS ground-level meteorological data, Rawinsonde upper-air meteorological data, ground-level oxidant data, skyradiometer data, skyview camera images, meteorological satellite IR image data and GOSAT validation lidar data. DMS written in PHP language demonstrates satellite-pass date and all acquired data.

  18. Surface albedo observations at Gusev Crater and Meridiani Planum, Mars

    USGS Publications Warehouse

    Bell, J.F.; Rice, M.S.; Johnson, J. R.; Hare, T.M.

    2008-01-01

    During the Mars Exploration Rover mission, the Pancam instrument has periodically acquired large-scale panoramic images with its broadband (739??338 nm) filter in order to estimate the Lambert bolometric albedo of the surface along each rover's traverse. In this work we present the full suite of such estimated albedo values measured to date by the Spirit and Opportunity rovers along their traverses in Gusev Crater and Meridiani Planum, respectively. We include estimated bolometric albedo values of individual surface features (e.g., outcrops, dusty plains, aeolian bed forms, wheel tracks, light-toned soils, and crater walls) as well as overall surface averages of the 43 total panoramic albedo data sets acquired to date. We also present comparisons to estimated Lambert albedo values taken from the Mars Global Surveyor Mars Orbiter Camera (MOC) along the rovers' traverses, and to the large-scale bolometric albedos of the sites from the Viking Orbiter Infrared Thermal Mapper (IRTM) and Mars Global Surveyor/Thermal Emission Spectrometer (TES). The ranges of Pancam-derived albedos at Gusev Crater (0.14 to 0.25) and in Meridiani Planum. (0.10 to 0.18) are in good agreement with IRTM, TES, and MOC orbital measurements. These data sets will be a useful tool and benchmark for future investigations of albodo variations with time, including measurements from orbital instruments like the Context Camera and High Resolution Imaging Science Experiment on Mars Reconnaissance Orbiter. Long-term, accurate albedo measurements could also be important for future efforts in climate modeling as well as for studies of active surface processes. Copyright 2008 by the American Geophysical Union.

  19. Surface albedo observations at Gusev Crater and Meridiani Planum, Mars

    NASA Astrophysics Data System (ADS)

    Bell, J. F.; Rice, M. S.; Johnson, J. R.; Hare, T. M.

    2008-05-01

    During the Mars Exploration Rover mission, the Pancam instrument has periodically acquired large-scale panoramic images with its broadband (739 +/- 338 nm) filter in order to estimate the Lambert bolometric albedo of the surface along each rover's traverse. In this work we present the full suite of such estimated albedo values measured to date by the Spirit and Opportunity rovers along their traverses in Gusev Crater and Meridiani Planum, respectively. We include estimated bolometric albedo values of individual surface features (e.g., outcrops, dusty plains, aeolian bed forms, wheel tracks, light-toned soils, and crater walls) as well as overall surface averages of the 43 total panoramic albedo data sets acquired to date. We also present comparisons to estimated Lambert albedo values taken from the Mars Global Surveyor Mars Orbiter Camera (MOC) along the rovers' traverses, and to the large-scale bolometric albedos of the sites from the Viking Orbiter Infrared Thermal Mapper (IRTM) and Mars Global Surveyor/Thermal Emission Spectrometer (TES). The ranges of Pancam-derived albedos at Gusev Crater (0.14 to 0.25) and in Meridiani Planum (0.10 to 0.18) are in good agreement with IRTM, TES, and MOC orbital measurements. These data sets will be a useful tool and benchmark for future investigations of albedo variations with time, including measurements from orbital instruments like the Context Camera and High Resolution Imaging Science Experiment on Mars Reconnaissance Orbiter. Long-term, accurate albedo measurements could also be important for future efforts in climate modeling as well as for studies of active surface processes.

  20. Hyperspectral remote sensing for monitoring species-specific drought impacts in southern California

    NASA Astrophysics Data System (ADS)

    Coates, Austin Reece

    A drought persisting since the winter of 2011-2012 has resulted in severe impacts on shrublands and forests in southern California, USA. Effects of drought on vegetation include leaf wilting, leaf abscission, and potential plant mortality. These impacts vary across plant species, depending on differences in species' adaptations to drought, rooting depth, and edaphic factors. During 2013 and 2014, Airborne Visible Infrared Imaging Spectrometer (AVIRIS) data were acquired seasonally over the Santa Ynez Mountains and Santa Ynez Valley north of Santa Barbara, California. To determine the impacts of drought on individual plant species, spectral mixture analysis was used to model a relative green vegetation fraction (RGVF) for each image date in 2013 and 2014. A July 2011 AVIRIS image acquired during the last nondrought year was used to determine a reference green vegetation (GV) endmember for each pixel. For each image date in 2013 and 2014, a three-endmember model using the 2011 pixel spectrum as GV, a lab nonphotosynthetic vegetation (NPV) spectrum, and a photometric shade spectrum was applied. The resulting RGVF provided a change in green vegetation cover relative to 2011. Reference polygons collected for 14 plant species and land cover classes were used to extract the RGVF values from each date. The deeply rooted tree species and tree species found in mesic areas appeared to be the least affected by the drought, whereas the evergreen chaparral showed the most extreme signs of distress. Coastal sage scrub had large seasonal variability; however, each year, it returned to an RGVF value only slightly below the previous year. By binning all the RGVF values together, a general decreasing trend was observed from the spring of 2013 to the fall of 2014. This study intends to lay the groundwork for future research in the area of multitemporal, hyperspectral remote sensing. With proposed plans for a hyperspectral sensor in space (HyspIRI), this type of research will prove to be invaluable in the years to come. This study also intends to be used as a benchmark to show how specific species of plants are being affected by a prolonged drought. The research performed in this study will provide a reference point for analysis of future droughts.

  1. 10. View of Draper darby chain loom from warp beam ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. View of Draper darby chain loom from warp beam end, patent date 1913, made by Drpaer Corporation, Hopedale, Massachusetts. Acquired ca. 1941. Note Draper-Northrop name on automatic spindle changer. - Riverdale Cotton Mill, Corner of Middle & Lower Streets, Valley, Chambers County, AL

  2. Intraoperative magnetic resonance imaging to update interactive navigation in neurosurgery: method and preliminary experience.

    PubMed

    Wirtz, C R; Bonsanto, M M; Knauth, M; Tronnier, V M; Albert, F K; Staubert, A; Kunze, S

    1997-01-01

    We report on the first successful intraoperative update of interactive image guidance based on an intraoperatively acquired magnetic resonance imaging (MRI) date set. To date, intraoperative imaging methods such as ultrasound, computerized tomography (CT), or MRI have not been successfully used to update interactive navigation. We developed a method of imaging patients intraoperatively with the surgical field exposed in an MRI scanner (Magnetom Open; Siemens Corp., Erlangen, Germany). In 12 patients, intraoperatively acquired 3D data sets were used for successful recalibration of neuronavigation, accounting for any anatomical changes caused by surgical manipulations. The MKM Microscope (Zeiss Corp., Oberkochen, Germany) was used as navigational system. With implantable fiducial markers, an accuracy of 0.84 +/- 0.4 mm for intraoperative reregistration was achieved. Residual tumor detected on MRI was consequently resected using navigation with the intraoperative data. No adverse effects were observed from intraoperative imaging or the use of navigation with intraoperative images, demonstrating the feasibility of recalibrating navigation with intraoperative MRI.

  3. Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

    PubMed Central

    Imajo, Kento; Yoneda, Masato; Kessoku, Takaomi; Ogawa, Yuji; Maeda, Shin; Sumida, Yoshio; Hyogo, Hideyuki; Eguchi, Yuichiro; Wada, Koichiro; Nakajima, Atsushi

    2013-01-01

    Research in nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), has been limited by the availability of suitable models for this disease. A number of rodent models have been described in which the relevant liver pathology develops in an appropriate metabolic context. These models are promising tools for researchers investigating one of the key issues of NASH: not so much why steatosis occurs, but what causes the transition from simple steatosis to the inflammatory, progressive fibrosing condition of steatohepatitis. The different rodent models can be classified into two large groups. The first includes models in which the disease is acquired after dietary or pharmacological manipulation, and the second, genetically modified models in which liver disease develops spontaneously. To date, no single rodent model has encompassed the full spectrum of human disease progression, but individual models can imitate particular characteristics of human disease. Therefore, it is important that researchers choose the appropriate rodent models. The purpose of the present review is to discuss the metabolic abnormalities present in the currently available rodent models of NAFLD, summarizing the strengths and weaknesses of the established models and the key findings that have furthered our understanding of the disease’s pathogenesis. PMID:24192824

  4. The role of close friends in African American adolescents' dating and sexual behavior.

    PubMed

    Harper, Gary W; Gannon, Christine; Watson, Susan G; Catania, Joseph A; Dolcini, M Margaret

    2004-11-01

    This study examined the role of close friends in the sexual lives of African American adolescents. Fifteen African American adolescents residing in an urban neighborhood participated in individual in-depth qualitative interviews. The findings suggest that close friends play a critical role in the dating and sexual behaviors of inner-city African American adolescents, as they appear to serve as socializing agents that impact how adolescents conceptualize and socially construct dating and sexual roles and behaviors. Close friends also play a significant role in acquiring new dating and sexual partners and in determining the course of dating and sexual relationships. Although females and males expressed similar expectations regarding sexual fidelity and condom use, they differed with regard to their method and process of talking with friends about dating and sex, their shared social constructions about dating and sexual roles and expectations, and their perceptions of the meaning of dating. We discuss the implications of the findings in terms of involving close friends in interventions focused on improving the sexual health of African American adolescents. Future directions for research with African American adolescents and sexuality are also discussed.

  5. New Observations of UV Emissions from Europa

    NASA Technical Reports Server (NTRS)

    McGrath, Melissa; Sparks, William

    2009-01-01

    The recent top prioritization of the Europa Jupiter System Mission for the next outer solar system flagship mission is refocusing attention on Europa and the other Galilean satellites and their contextual environments in the Jupiter system. Surface sputtering by magnetospheric plasma generates a tenuous atmosphere for Europa, dominated by 02 gas. This tenuous gas is in turn excited by plasma electrons, producing ultraviolet and visible emissions. Two sets of imaging observations have been published to date, UV images from the Hubble Space Telescope, and visible eclipse images from Cassini. Three additional sets of HST UV observations were acquired in February 2007, April 2007 and June 2009. The signal to noise ratio in these data are not high, however, given the paucity of data and its increasing importance in terms of planning for EJSM, we have attempted to extract as much new information as possible from these data. This talk will summarize our analysis to date, and discuss them in terms of existing models, which attempt to explain the image morphology either in terms of the underlying source production and loss processes, or in terms of the plasma interaction with the exosphere.

  6. 78 FR 70067 - Marine Mammals; Receipt of Applications for Permit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... requests a permit to photograph polar bears (Ursus maritimus) in the vicinity of Kaktovik/Barter Island... species unless Federal authorization is acquired that allows such activities. DATES: We must receive... carry out our conservation responsibilities for affected species, and in consideration of the Marine...

  7. Operation and performance of the Mars Exploration Rover imaging system on the Martian surface

    NASA Technical Reports Server (NTRS)

    Maki, Justin N.; Litwin, Todd; Herkenhoff, Ken

    2005-01-01

    The Imaging System on the Mars Exploration Rovers has successfully operated on the surface of Mars for over one Earth year. An overview of the surface imaging activities is provided, along with a summary of the image data acquired to date.

  8. 78 FR 29387 - Government-Owned Inventions, Available for Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-20

    ... Trademark Office, and are available for licensing. DATES: May 20, 2013. FOR FURTHER INFORMATION CONTACT... Resonators for Suppression of Acceleration-Induced Frequency Fluctuations; NASA Case No.: DRC-012-011: System... Multiplexing and Acquiring Data from Multiple Optical Fibers using a Single Data Channel of an Optical...

  9. 75 FR 15403 - Information Collection, Procurement of Agricultural Commodities for Foreign Donation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-29

    ... Credit Corporation (CCC) is requesting comments from all interested individuals and organizations on an... opportunities for potential vendors while allowing CCC to efficiently acquire commodities. DATES: Comments on... sells or donates commodities to promote economic development. To accommodate these donations, CCC issues...

  10. Experimental Gonococcal Infection in Male Volunteers: Cumulative Experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC

    PubMed Central

    Hobbs, Marcia M.; Sparling, P. Frederick; Cohen, Myron S.; Shafer, William M.; Deal, Carolyn D.; Jerse, Ann E.

    2011-01-01

    Experimental infection of male volunteers with Neisseria gonorrhoeae is safe and reproduces the clinical features of naturally acquired gonococcal urethritis. Human inoculation studies have helped define the natural history of experimental infection with two well-characterized strains of N. gonorrhoeae, FA1090 and MS11mkC. The human model has proved useful for testing the importance of putative gonococcal virulence factors for urethral infection in men. Studies with isogenic mutants have improved our understanding of the requirements for gonococcal LOS structures, pili, opacity proteins, IgA1 protease, and the ability of infecting organisms to obtain iron from human transferrin and lactoferrin during uncomplicated urethritis. The model also presents opportunities to examine innate host immune responses that may be exploited or improved in development and testing of gonococcal vaccines. Here we review results to date with human experimental gonorrhea. PMID:21734909

  11. Uterus transplantation: Experimental animal models and recent experience in humans

    PubMed Central

    Şahin, Sadık; Selçuk, Selçuk; Eroğlu, Mustafa; Karateke, Ateş

    2015-01-01

    Uterus transplantation has been considered as an alternative management modality in the last few years for adoption or gestational surrogacy for women with absence of uterus due to congenital or acquired reasons. Surrogacy is legal in only a few countries because of ethical, social and legal issues. Up to date, a total of 11 uterus transplantation cases have been reported in which uteri were harvested from ten live donors and one donor with brain death. After unsuccessful attempt of first uterus transplantation, many studies have been conducted in animals and these experimental models enabled our knowledge to increase on this topic. First experimental studies were performed in rodents; later uterus transplantation was accomplished in sheep, pigs and rabbits. Recently, researches in non-human primates have led the experience regarding transplantation technique and success to improve. In this review, we reviewed the experimental animal researches in the area of uterus transplantation and recent experience in humans. PMID:28913039

  12. Broadband, high-resolution investigation of advanced absorption line shapes at high temperature

    NASA Astrophysics Data System (ADS)

    Schroeder, Paul J.; Cich, Matthew J.; Yang, Jinyu; Swann, William C.; Coddington, Ian; Newbury, Nathan R.; Drouin, Brian J.; Rieker, Gregory B.

    2017-08-01

    Spectroscopic studies of planetary atmospheres and high-temperature processes (e.g., combustion) require absorption line-shape models that are accurate over extended temperature ranges. To date, advanced line shapes, like the speed-dependent Voigt and Rautian profiles, have not been tested above room temperature with broadband spectrometers. We investigate pure water vapor spectra from 296 to 1305 K acquired with a dual-frequency comb spectrometer spanning from 6800 to 7200 c m-1 at a point spacing of 0.0033 c m-1 and absolute frequency accuracy of <3.3 ×10-6c m-1 . Using a multispectral fitting analysis, we show that only the speed-dependent Voigt accurately models this temperature range with a single power-law temperature-scaling exponent for the broadening coefficients. Only the data from the analysis using this profile fall within theoretical predictions, suggesting that this mechanism captures the dominant narrowing physics for these high-temperature conditions.

  13. Systematic study of magnetar outbursts

    NASA Astrophysics Data System (ADS)

    Coti Zelati, F.; Rea, N.; Pons, J. A.; Campana, S.; Esposito, P.

    2017-12-01

    We present the results of the systematic study of all magnetar outbursts observed to date through a reanalysis of data acquired in about 1100 X-ray observations. We track the temporal evolution of the luminosity for all these events, model empirically their decays, and estimate the characteristic decay time-scales and the energy involved. We study the link between different parameters (maximum luminosity increase, outburst peak luminosities, quiescent X-ray and bolometric luminosities, energetics, decay time-scales, magnetic field, spin-down luminosity and age), and reveal several correlations between different quantities. We discuss our results in the framework of the models proposed to explain the triggering mechanism and evolution of magnetar outbursts. The study is complemented by the Magnetar Outburst Online Catalog (http://www.magnetars.ice.csic.es), an interactive database where the user can plot any combination of the parameters derived in this work and download all reduced data.

  14. Animal Model Development for the Penn State Pediatric Ventricular Assist Device

    PubMed Central

    Carney, Elizabeth L.; Clark, J. Brian; Myers, John L.; Peterson, Rebecca; Wilson, Ronald P.; Weiss, William J.

    2009-01-01

    In March 2004, the National Heart, Lung, and Blood Institute (NHLBI) awarded five contracts to develop devices providing circulatory support for infants and small children with congenital and acquired cardiac disease. Since 2004, the team at Penn State College of Medicine has developed a pneumatically-actuated ventricular assist device (VAD) with mechanical tilting disk valves. To date, hemodynamic performance, thrombogenesis, and hemolysis have been chronically evaluated in 16 animals, including 4 pygmy goats and 12 sheep. Major complications, mainly respiratory failure, have been encountered and resolved by a multi-disciplinary team. Multi-modal analgesia, appropriate antibiotic therapy, and attentive animal care have contributed to successful outcomes. Time after implant has ranged from 0–40 days. Most recently, a sheep implanted with Version 3 Infant VAD was electively terminated at 35 days post-implant, with no major adverse events. This report describes a successful in vivo model for evaluating a pediatric VAD. PMID:19849686

  15. Spectral estimates of solar radiation intercepted by corn canopies

    NASA Technical Reports Server (NTRS)

    Bauer, M. E. (Principal Investigator); Daughtry, C. S. T.; Gallo, K. P.

    1982-01-01

    Reflectance factor data were acquired with a Landsat band radiometer throughout two growing seasons for corn (Zea mays L.) canopies differing in planting dates, populations, and soil types. Agronomic data collected included leaf area index (LAI), biomass, development stage, and final grain yields. The spectral variable, greenness, was associated with 78 percent of the variation in LAI over all treatments. Single observations of LAI or greenness have limited value in predicting corn yields. The proportions of solar radiation intercepted (SRI) by these canopies were estimated using either measured LAI or greenness. Both SRI estimates, when accumulated over the growing season, accounted for approximately 65 percent of the variation in yields. Models which simulated the daily effects of weather and intercepted solar radiation on growth had the highest correlations to grain yields. This concept of estimating intercepted solar radiation using spectral data represents a viable approach for merging spectral and meteorological data for crop yield models.

  16. A novel cause of community-acquired pneumonia in a young immunocompetent host.

    PubMed

    James, Nicholas; Gilman, Matthew; Duncan, Robert; Gray, Anthony

    2016-09-01

    Diffuse pulmonary infiltrates represent a common problem encountered by pulmonologists. The differential diagnosis is extensive and includes infectious, inflammatory, environmental and malignant conditions. Appropriate evaluation, aside from a thorough history and physical examination, includes serologic, radiographic and procedural elements. We describe a case of a healthy male with diffuse pulmonary infiltrates. Work up revealed a novel infectious etiology. Although this particular microorganism has been described to cause native valve endocarditis, recurrent breast abscesses, osteomyelitis and bacteremia, it has to date not been described as a cause for community acquired pneumonia in immunocompetent hosts. © 2014 John Wiley & Sons Ltd.

  17. Hanford Site Composite Analysis Technical Approach Description: Groundwater

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Budge, T. J.

    The groundwater facet of the revised CA is responsible for generating predicted contaminant concentration values over the entire analysis spatial and temporal domain. These estimates will be used as part of the groundwater pathway dose calculation facet to estimate dose for exposure scenarios. Based on the analysis of existing models and available information, the P2R Model was selected as the numerical simulator to provide these estimates over the 10,000-year temporal domain of the CA. The P2R Model will use inputs from initial plume distributions, updated for a start date of 1/1/2017, and inputs from the vadose zone facet, created bymore » a tool under development as part of the ICF, to produce estimates of hydraulic head, transmissivity, and contaminant concentration over time. A recommendation of acquiring 12 computer processors and 2 TB of hard drive space is made to ensure that the work can be completed within the anticipated schedule of the revised CA.« less

  18. 26 CFR 1.475(c)-2 - Definitions-security.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... paragraph (c)(1) if, on the date the taxpayer acquires the residual interest, the present value of the anticipated tax liabilities associated with holding the interest exceeds the sum of— (i) The present value of the expected future distributions on the interest; and (ii) The present value of the anticipated tax...

  19. Implicit and Explicit Learning in Individuals with Agrammatic Aphasia

    ERIC Educational Resources Information Center

    Schuchard, Julia; Thompson, Cynthia K.

    2014-01-01

    Implicit learning is a process of acquiring knowledge that occurs without conscious awareness of learning, whereas explicit learning involves the use of overt strategies. To date, research related to implicit learning following stroke has been largely restricted to the motor domain and has rarely addressed implications for language. The present…

  20. 76 FR 62469 - Notice of Applications for Deregistration Under Section 8(f) of the Investment Company Act of 1940

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-07

    ..., SEC, Division of Investment Management, Office of Investment Company Regulation, 100 F Street, NE... Management Corp., investment adviser for the acquiring fund, and Hartford Investment Financial Services, LLC... Columbia Management Investment Advisers, LLC, applicant's investment adviser. Filing Date: The application...

  1. 32 CFR 326.8 - Procedures for requesting access.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) PRIVACY PROGRAM NATIONAL RECONNAISSANCE OFFICE PRIVACY ACT PROGRAM § 326.8 Procedures for requesting... available under the Privacy Act, shall address the request in writing to the Privacy Act Coordinator... Number and the date that status was acquired. (ii) The parent or guardian of a minor or of a person...

  2. 32 CFR 326.8 - Procedures for requesting access.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) PRIVACY PROGRAM NATIONAL RECONNAISSANCE OFFICE PRIVACY ACT PROGRAM § 326.8 Procedures for requesting... available under the Privacy Act, shall address the request in writing to the Privacy Act Coordinator... Number and the date that status was acquired. (ii) The parent or guardian of a minor or of a person...

  3. 7 CFR 1485.23 - Miscellaneous provisions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...., participation fees, proceeds of sales, refunds of value added taxes (VAT), the expenditures for which have been... goods with a value of $100 acquired in furtherance of program activities. The inventory shall list and number each item and include the date of purchase or acquisition, cost of purchase, replacement value...

  4. 78 FR 16859 - Office of the Director, National Institutes of Health; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... funding cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.14, Intramural Research Training....936, NIH Acquired Immunodeficiency Syndrome Research Loan Repayment Program; 93.187, Undergraduate... Programs Special Emphasis Panel; Research Resource of Human Organs and Tissues. Date: April 2, 2013. Time...

  5. 50 CFR 21.2 - Scope of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PLANTS (CONTINUED) MIGRATORY BIRD PERMITS Introduction § 21.2 Scope of regulations. (a) Migratory birds, their parts, nests, or eggs, lawfully acquired prior to the effective date of Federal protection under the Migratory Bird Treaty Act (16 U.S.C. 703-712) may be possessed or transported without a permit...

  6. Use of video in the Virginia Highway and Transportation Research Council.

    DOT National Transportation Integrated Search

    1984-01-01

    Described in this report is the video equipment recently acquired by the Council and how it has been used to date. Also discussed are the many other ways this equipment can and probably will be used in the future, not only at the Council, but in oper...

  7. 12 CFR 702.202 - Prompt corrective action for “undercapitalized” credit unions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... open new branches; (4) Restrict member business loans. Beginning the effective date of classification as “undercapitalized” or lower, not increase the total dollar amount of member business loans..., branching, new lines of business. Prohibit a credit union from, directly or indirectly, acquiring any...

  8. Landforms, sediments and dates to constrain rates and style of marine-influenced ice sheet decay; the BRITICE-CHRONO project.

    NASA Astrophysics Data System (ADS)

    Clark, Chris

    2014-05-01

    Uncertainty exists regarding the future mass of the Antarctic and Greenland ice sheets and how they will respond to forcings from sea level, and atmospheric and ocean temperatures. If we want to know more about the mechanisms and rate of change of shrinking ice sheets, then why not examine an ice sheet that has fully disappeared and track its retreat through time? If achieved in enough detail such information on ice retreat could be a data-rich playground for improving the next breed of numerical ice sheet models to be used in ice and sea level forecasting. We regard that the last British-Irish Ice Sheet is a good target for this work, on account of its small size, density of information and with its numerous researchers already investigating it. Geomorphological mapping across the British Isles and the surrounding continental shelf has revealed the nature and distribution of glacial landforms. Here we demonstrate how such data have been used to build a pattern of ice margin retreat. The BRITICE-CHRONO consortium of Quaternary scientists and glaciologists, are now working on a project running from 2012 - 2017 to produce an ice sheet wide database of geochronometric dates to constrain and then understand ice margin retreat. This is being achieved by focusing on 8 transects running from the continental shelf edge to a short distance (10s km) onshore and acquiring marine and terrestrial samples for geochronometric dating. The project includes funding for 587 radiocarbon, 140 OSL and 158 TCN samples for surface exposure dating; with sampling accomplished by two research cruises and 16 fieldwork campaigns. Results will reveal the timing and rate of change of ice margin recession for each transect, and combined with existing landform and dating databases, will be used to build an ice sheet-wide empirical reconstruction of retreat. Simulations using two numerical ice sheet models, fitted against the margin data, will help us understand the nature and significance of sea-level rise and ocean/atmosphere forcing on influencing the rate of retreat and ice sheet demise and the effect that bed topography has in controlling this.

  9. [Present situation of awareness of acquired immune deficiency syndrome (AIDS) knowledge and AIDS-related behaviors among youth students in gay dating sites].

    PubMed

    2017-06-18

    To investigate the awareness of acquired immune deficiency syndrome (AIDS) knowledge and AIDS-related behaviors among youth students in gay dating sites, and to provide evidences for AIDS prevention education through the internet. The students in gay dating sites, selected by a snowball sampling, were interviewed by questionnaires. Chi-square tests were used to analyze the awareness of AIDS knowledge among the students of different characteristics. The Logistic regression was used to analyze the factors associated with ever testing for HIV. In the study, 469 youth students in gay dating sites filled in the questionnaires, and a total of 442 (94.2%) valid samples were collected. The awareness of HIV/AIDS knowledge for the public among the youth students in gay dating sites was 83.9% (371).The awareness of HIV/AIDS knowledge for the youth students was 77.1% (341), and the rate of ever testing for HIV was 52.0% (230). The awareness of HIV/AIDS knowledge for the public in the students were different in different age groups (P=0.001), different marital statuses (P<0.001), different sexual orientations (P<0.001), and different genders of the first sexual partner (P<0.001). The awareness of HIV/AIDS knowledge for the youth students were different in different age groups (P=0.010), different marital status (P=0.004), different sexual orientations (P<0.001), and different genders of the first sexual partner (P<0.001). The rate of ever having sexual intercourse among the youth students in gay dating sites was 75.1% (332), and the rate of multiple sexual partnerships among the youth students was 41.3% (137). Compared with homosexual orientation, sexual orientation as heterosexual (OR=0.282, 95%CI: 0.151 to 0.528) and not sure (OR=0.175, 95%CI: 0.035 to 0.885) were risk factors of ever testing for HIV. Multiple sexual partnerships (OR=2.103, 95%CI: 1.278 to 3.462) were promoting factors of ever testing for HIV. The rate of high-risk behaviors among the youth students in gay dating sites was high. The concern should be raised to heterosexual male students who had tendency to homosexual behavior. The AIDS prevention education should be developed in gay dating sites, to improve the self-protection awareness of the youth students.

  10. Multiscale sagebrush rangeland habitat modeling in the Gunnison Basin of Colorado

    USGS Publications Warehouse

    Homer, Collin G.; Aldridge, Cameron L.; Meyer, Debra K.; Schell, Spencer J.

    2013-01-01

    North American sagebrush-steppe ecosystems have decreased by about 50 percent since European settlement. As a result, sagebrush-steppe dependent species, such as the Gunnison sage-grouse, have experienced drastic range contractions and population declines. Coordinated ecosystem-wide research, integrated with monitoring and management activities, is needed to help maintain existing sagebrush habitats; however, products that accurately model and map sagebrush habitats in detail over the Gunnison Basin in Colorado are still unavailable. The goal of this project is to provide a rigorous large-area sagebrush habitat classification and inventory with statistically validated products and estimates of precision across the Gunnison Basin. This research employs a combination of methods, including (1) modeling sagebrush rangeland as a series of independent objective components that can be combined and customized by any user at multiple spatial scales; (2) collecting ground measured plot data on 2.4-meter QuickBird satellite imagery in the same season the imagery is acquired; (3) modeling of ground measured data on 2.4-meter imagery to maximize subsequent extrapolation; (4) acquiring multiple seasons (spring, summer, and fall) of Landsat Thematic Mapper imagery (30-meter) for optimal modeling; (5) using regression tree classification technology that optimizes data mining of multiple image dates, ratios, and bands with ancillary data to extrapolate ground training data to coarser resolution Landsat Thematic Mapper; and 6) employing accuracy assessment of model predictions to enable users to understand their dependencies. Results include the prediction of four primary components including percent bare ground, percent herbaceous, percent shrub, and percent litter, and four secondary components including percent sagebrush (Artemisia spp.), percent big sagebrush (Artemisia tridentata), percent Wyoming sagebrush (Artemisia tridentata wyomingensis), and shrub height (centimeters). Results were validated with an independent accuracy assessment, with root mean square error values ranging from 3.5 (percent big sagebrush) to 10.8 (percent bare ground) at the QuickBird scale, and from 4.5 (percent Wyoming sagebrush) to 12.4 (percent herbaceous) at the full Landsat scale. These results offer significant improvement in sagebrush ecosystem quantification across the Gunnison Basin, and also provide maximum flexibility to users to employ for a wide variety of applications. Further refinement of these remote sensing component predictions in the future will be most likely achieved by focusing on more extensive ground plot sampling, employing new high and moderate-resolution satellite sensors that offer additional spectral bands for vegetation discrimination, and capturing more dates of satellite imagery to better represent phenological variation.

  11. Blood recipient unable to recover damages based on fraud.

    PubMed

    1995-05-05

    A court ruled that [name removed] is unable to sue for fraud after acquiring HIV through a blood transfusion in 1982. [Name removed], who sued the hospital, her cardiologist, and two physicians, claimed she did not learn she had received a blood transfusion until after she was diagnosed with AIDS. She tested positive for HIV antibodies in March 1992 and was diagnosed with AIDS. The Supreme Court said a cause of action for actual fraud must be filed within six years from the date of the fraudulent act or two years from the date the plaintiff discovered the fraud.

  12. 17 CFR 1.33 - Monthly and confirmation statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... close of the last business day of each month or as of any regular monthly date selected, except for... customer— (i) The open contracts with prices at which acquired; (ii) The net unrealized profits or losses... disbursed to such customer and realized profits and losses; and (2) For each option customer and foreign...

  13. 17 CFR 1.33 - Monthly and confirmation statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... close of the last business day of each month or as of any regular monthly date selected, except for... customer— (i) The open contracts with prices at which acquired; (ii) The net unrealized profits or losses... disbursed to such customer and realized profits and losses; and (2) For each option customer and foreign...

  14. The Development of Yes-No Question Intonation in Puerto Rican Spanish

    ERIC Educational Resources Information Center

    Armstrong, Meghan Elizabeth

    2012-01-01

    Intonational development has been an area of interest during the past four decades, from the perspectives of both production and perception. But relatively few conclusions have been made about how children acquire the intonational component of their grammar. To date, prior studies of intonational development have not included a fine-grained…

  15. 12 CFR 211.23 - Nonbanking activities of foreign banking organizations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... reflected in its annual reports (FR Y-7) filed with the Board. (2) Continuing activities and investments. (i... continue to engage in activities or retain investments commenced or acquired prior to the end of the first.... (ii) Termination or divestiture. Activities commenced or investments made after that date shall be...

  16. 12 CFR 23.4 - Investment in personal property.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... business or for entry into the leasing business; and (2) The bank's aggregate investment in property held... shall either liquidate the off-lease property or re-lease it under a conforming lease as soon as practicable. Liquidation or re-lease must occur not later than five years from the date that the bank acquires...

  17. 12 CFR 23.4 - Investment in personal property.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... business or for entry into the leasing business; and (2) The bank's aggregate investment in property held... shall either liquidate the off-lease property or re-lease it under a conforming lease as soon as practicable. Liquidation or re-lease must occur not later than five years from the date that the bank acquires...

  18. 12 CFR 23.4 - Investment in personal property.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... business or for entry into the leasing business; and (2) The bank's aggregate investment in property held... shall either liquidate the off-lease property or re-lease it under a conforming lease as soon as practicable. Liquidation or re-lease must occur not later than five years from the date that the bank acquires...

  19. Enhancing Writing Skills of EFL Learners through Blogging

    ERIC Educational Resources Information Center

    Akdag, Emrah; Özkan, Yonca

    2017-01-01

    In such a rapidly developing world, it has been inevitable to integrate some modern assessment approaches and tools into English teaching. Hence, several up to date Formative Assessment Tools have been used by teachers during the learning process to modify teaching and learning activities by means of acquiring qualitative feedback. Blogs or…

  20. 77 FR 68812 - Renewal of Agency Information Collection for Class III Gaming; Tribal Revenue Allocation Plans...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ... authorized by OMB Control Number 1076-0149, Tribal Revenue Allocation Plans authorized by OMB Control Number 1076-0152, and Gaming on Trust Lands Acquired After October 17, 1988 authorized by OMB Control Number 1076-0158. These information collections expire November 30, 2012. DATE: Interested persons are invited...

  1. From In-Service Teacher Development to School Improvement: Factors of Learning Transfer in Teacher Education

    ERIC Educational Resources Information Center

    Dreer, Benjamin; Dietrich, Julia; Kracke, Bärbel

    2017-01-01

    In-service teacher development programs are perceived as a common way to foster school improvement. Nevertheless, program evaluation to date ends with the assessment of acquired knowledge, skills, and motivation, frequently disregarding the actual learning transfer and its conditions. This study aimed to investigate how individual and situational…

  2. 77 FR 63422 - Proposed Collection; Comment Request for Information Collection Tools

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... of tax-exempt bonds to rebate arbitrage profits earned on nonpurpose investments acquired with the... by Qualified Retirement Plan After Annuity Starting Dates (Sec. 1.417(e)-1); REG-105946-00 (TD 8995... Specific Amount in Gross Income; Form 6118, Claim of Income Tax Return Preparer Penalties; Form 5500-EZ...

  3. Up Close and Personal

    NASA Image and Video Library

    2014-05-08

    This image is one of the highest-resolution MDIS observations to date! Many craters of varying degradation states are visible, as well as gentle terrain undulations. Very short exposure times are needed to make these low-altitude observations while the spacecraft is moving quickly over the surface; thus the images are slightly noisier than typical MDIS images. This image was acquired as a high-resolution targeted observation. Targeted observations are images of a small area on Mercury's surface at resolutions much higher than the 200-meter/pixel morphology base map. It is not possible to cover all of Mercury's surface at this high resolution, but typically several areas of high scientific interest are imaged in this mode each week. Date acquired: March 15, 2014 Image Mission Elapsed Time (MET): 37173522 Image ID: 5936740 Instrument: Narrow Angle Camera (NAC) of the Mercury Dual Imaging System (MDIS) Center Latitude: 71.91° Center Longitude: 232.7° E Resolution: 5 meters/pixel Scale: The image is approximately 8.3 km (5.2 mi.) across. Incidence Angle: 79.4° Emission Angle: 4.0° Phase Angle: 83.4° http://photojournal.jpl.nasa.gov/catalog/PIA18370

  4. Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 4: Prognostic value of B-type natriuretic peptides (BNP and NT-proBNP) in community-acquired pneumonia.

    PubMed

    Hodgson, David; Nee, Patrick; Sultan, Laith

    2012-10-01

    A short cut review was carried out to establish the prognostic value of B-type natriuretic peptides (BNP and NT-proBNP) in community acquired pneumonia (CAP). Three cohort studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line was that B-type natriuretic peptides have prognostic value in CAP but further prospective studies were needed to assess their application in clinical practice.

  5. Brain Volumetric Correlates of Autism Spectrum Disorder Symptoms in Attention Deficit/Hyperactivity Disorder

    PubMed Central

    O’Dwyer, Laurence; Tanner, Colby; van Dongen, Eelco V.; Greven, Corina U.; Bralten, Janita; Zwiers, Marcel P.; Franke, Barbara; Oosterlaan, Jaap; Heslenfeld, Dirk; Hoekstra, Pieter; Hartman, Catharina A.; Rommelse, Nanda; Buitelaar, Jan K.

    2014-01-01

    Autism spectrum disorder (ASD) symptoms frequently occur in subjects with attention deficit/hyperactivity disorder (ADHD). While there is evidence that both ADHD and ASD have differential structural correlates, no study to date has investigated these structural correlates within a framework that robustly accounts for the phenotypic overlap between the two disorders. The presence of ASD symptoms was measured by the parent-reported Children’s Social and Behavioural Questionnaire (CSBQ) in ADHD subjects (n = 180), their unaffected siblings (n = 118) and healthy controls (n = 146). ADHD symptoms were assessed by a structured interview (K-SADS-PL) and the Conners’ ADHD questionnaires. Whole brain T1-weighted MPRAGE images were acquired and the structural MRI correlates of ASD symptom scores were analysed by modelling ASD symptom scores against white matter (WM) and grey matter (GM) volumes using mixed effects models which controlled for ADHD symptom levels. ASD symptoms were significantly elevated in ADHD subjects relative to both controls and unaffected siblings. ASD scores were predicted by the interaction between WM and GM volumes. Increasing ASD score was associated with greater GM volume. Equivocal results from previous structural studies in ADHD and ASD may be due to the fact that comorbidity has not been taken into account in studies to date. The current findings stress the need to account for issues of ASD comorbidity in ADHD. PMID:24979066

  6. Method for distributed object communications based on dynamically acquired and assembled software components

    NASA Technical Reports Server (NTRS)

    Sundermier, Amy (Inventor)

    2002-01-01

    A method for acquiring and assembling software components at execution time into a client program, where the components may be acquired from remote networked servers is disclosed. The acquired components are assembled according to knowledge represented within one or more acquired mediating components. A mediating component implements knowledge of an object model. A mediating component uses its implemented object model knowledge, acquired component class information and polymorphism to assemble components into an interacting program at execution time. The interactions or abstract relationships between components in the object model may be implemented by the mediating component as direct invocations or indirect events or software bus exchanges. The acquired components may establish communications with remote servers. The acquired components may also present a user interface representing data to be exchanged with the remote servers. The mediating components may be assembled into layers, allowing arbitrarily complex programs to be constructed at execution time.

  7. Evaluating the reliability of Late Quaternary landform ages: Integrating 10Be cosmogenic surface exposure dating with U-series dating of pedogenic carbonate on alluvial and fluvial deposits, Sonoran desert, California

    NASA Astrophysics Data System (ADS)

    Blisniuk, K.; Sharp, W. D.

    2015-12-01

    To assess the reliability of Quaternary age determinations of alluvial and fluvial deposits across the Sonoran Desert (Coachella Valley and Anza Borrego) in southern California, we applied both 10Be exposure age dating of surface clasts and U-series dating of pedogenic carbonate from subsurface clast-coatings to the same deposits. We consider agreement between dates from the two techniques to indicate reliable age estimates because each technique is subject to distinct assumptions and therefore their systematic uncertainties are largely independent. 10Be exposure dates should yield maximum ages when no correction is made for inheritance and post-depositional erosion is negligible. U-series dating, in contrast, provides minimum dates because pedogenic carbonate forms after deposition. Our results show that: (1) For deposits ca. 70 ka or younger, 10Be and U-series dates were generally concordant. We note, however, that in most cases U-series soil dates exceed 10Be exposure dates that are corrected for inheritance when using 10Be in modern alluvium. This suggests that 10Be concentrations of modern alluvium may exceed the 10Be acquired by late Pleistocene deposits during fluvial transport and hillslope residence (i.e., Pleistocene inherited 10Be). (2) For deposits older than ~70 ka, U-series dates are significantly younger than the 10Be dates. This implies that U-series dates in this region may significantly underestimate the depositional age of older alluvium, probably because of delayed onset of deposition, slow accumulation, or poor preservation of secondary carbonate in response to climatic controls. Thus, whenever possible, multiple dating methods should be applied to obtain reliable ages for late Quaternary deposits.

  8. Application of backpack Lidar to geological cross-section measurement

    NASA Astrophysics Data System (ADS)

    Lin, Jingyu; Wang, Ran; Xiao, Zhouxuan; Li, Lu; Yao, Weihua; Han, Wei; Zhao, Baolin

    2017-11-01

    As the traditional geological cross section measurement, the artificial traverse method was recently substituted by using point coordinates data. However, it is still the crux of the matter that how to acquire the high-precision point coordinates data quickly and economically. Thereby, the backpack Lidar is presented on the premise of the principle of using point coordinates in this issue. Undoubtedly, Lidar technique, one of booming and international active remote sensing techniques, is a powerful tool in obtaining precise topographic information, high-precision 3-D coordinates and building a real 3-D model. With field practice and date processing indoors, it is essentially accomplished that geological sections maps could be generated simply, accurately and automatically in the support of relevant software such as ArcGIS and LiDAR360.

  9. Heat strain models applicable for protective clothing: Comparison of core temperature response. Technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gonzalez, R.R.; McLellan, T.M.; Withey, W.R.

    This report represents the results of TTCP-UTP6 efforts on modeling aspects when chemical protective ensembles are worn which need to be considered in warm environments. Since 1983, a significant data base has been collected using human experimental studies and wide clothing systems from which predictive modeling equations have been developed with individuals working in temperate and hot environments, but few comparisons of the -- results from various model outputs have ever been carried out. This initial comparison study was part of a key technical area (KIA) project for The Technical Cooperation Program (TTCP) UTP-6 working party. A modeling workshop wasmore » conducted in Toronto, Canada on 9-10 June 1994 to discuss the data reduction and results acquired in an initial clothing analysis study of TTCP using various chemical protective garments. To our knowledge, no comprehensive study to date has ever focused on comparing experimental results using an international standardized heat stress procedure matched to physiological outputs from various model predictions in individuals dressed in chemical protective clothing systems. This is the major focus of this TTCP key technical study. This technical report covers one aspect of the working party`s results.« less

  10. Laser induced fluorescence as a diagnostic tool integrated into a scanning fiber endoscope for mouse imaging

    NASA Astrophysics Data System (ADS)

    Brown, Christopher M.; Maggio-Price, Lillian; Seibel, Eric J.

    2007-02-01

    Scanning fiber endoscope (SFE) technology has shown promise as a minimally invasive optical imaging tool. To date, it is capable of capturing full-color 500-line images, at 15 Hz frame rate in vivo, as a 1.6 mm diameter endoscope. The SFE uses a singlemode optical fiber actuated at mechanical resonance to scan a light spot over tissue while backscattered or fluorescent light at each pixel is detected in time series using several multimode optical fibers. We are extending the capability of the SFE from a RGB reflectance imaging device to a diagnostic tool by imaging laser induced fluorescence (LIF) in tissue, allowing for correlation of endogenous fluorescence to tissue state. Design of the SFE for diagnostic imaging is guided by a comparison of single point spectra acquired from an inflammatory bowel disease (IBD) model to tissue histology evaluated by a pathologist. LIF spectra were acquired by illuminating tissue with a 405 nm light source and detecting intrinsic fluorescence with a multimode optical fiber. The IBD model used in this study was mdr1a-/- mice, where IBD was modulated by infection with Helicobacter bilis. IBD lesions in the mouse model ranged from mild to marked hyperplasia and dysplasia, from the distal colon to the cecum. A principle components analysis (PCA) was conducted on single point spectra of control and IBD tissue. PCA allowed for differentiation between healthy and dysplastic tissue, indicating that emission wavelengths from 620 - 650 nm were best able to differentiate diseased tissue and inflammation from normal healthy tissue.

  11. Using stereophotogrammetric technology for obtaining intraoral digital impressions of implants.

    PubMed

    Pradíes, Guillermo; Ferreiroa, Alberto; Özcan, Mutlu; Giménez, Beatriz; Martínez-Rus, Francisco

    2014-04-01

    The procedure for making impressions of multiple implants continues to be a challenge, despite the various techniques proposed to date. The authors' objective in this case report is to describe a novel digital impression method for multiple implants involving the use of stereophotogrammetric technology. The authors present three cases of patients who had multiple implants in which the impressions were obtained with this technology. Initially, a stereo camera with an infrared flash detects the position of special flag abutments screwed into the implants. This process is based on registering the x, y and z coordinates of each implant and the distances between them. This information is converted into a stereolithographic (STL) file. To add the soft-tissue information, the user must obtain another STL file by using an intraoral or extraoral scanner. In the first case presented, this information was acquired from the plaster model with an extraoral scanner; in the second case, from a Digital Imaging and Communication in Medicine (DICOM) file of the plaster model obtained with cone-beam computed tomography; and in the third case, through an intraoral digital impression with a confocal scanner. In the three cases, the frameworks manufactured from this technique showed a correct clinical passive fit. At follow-up appointments held six, 12 and 24 months after insertion of the prosthesis, no complications were reported. Stereophotogrammetric technology is a viable, accurate and easy technique for making multiple implant impressions. Clinicians can use stereophotogrammetric technology to acquire reliable digital master models as a first step in producing frameworks with a correct passive fit.

  12. Electrical Resistivity Structure of the Valles Caldera, New Mexico, USA: Results From 3D Inversion of Modern and Legacy Magnetotelluric Data Collected by Industry and the Summer of Applied Geophysical Experience (SAGE).

    NASA Astrophysics Data System (ADS)

    Feucht, D. W.; Bedrosian, P.; Jiracek, G. R.; Pellerin, L.; Nettleton, C. E.

    2017-12-01

    The Valles caldera, in north-central New Mexico, USA, is a 20-km wide topographic depression in the Jemez Mountains volcanic complex that formed during two massive ignimbrite eruptions 1.65 and 1.26 Ma. Post-collapse volcanic activity in the caldera includes the rise of a 1 km high resurgent dome, periodic eruptions of the Valles rhyolite along ring fractures, and the presence of a geothermal reservoir beneath the western caldera with temperatures in excess of 300°C at a mere 2 km depth. We present an electrical resistivity model of the upper crust from three-dimensional (3D) inversion of broadband (100 Hz to 600 s) magnetotelluric (MT) data collected in and around the Valles caldera. The Summer of Applied Geophysical Experience (SAGE) has been acquiring geophysical data in the northern Rio Grande rift for more than three decades (1983-2017). Included in that vast dataset are over 60 broadband magnetotelluric soundings that have recently been cataloged, geo-located, and digitized for use in modern geophysical processing and modeling. The resistivity models presented here were produced by inverting a subset of SAGE MT data along with 30 broadband MT soundings acquired by the Unocal Corporation in 1983 for geothermal exploration of the caldera. We use the 3D inversion algorithm ModEM (Egbert and Kelbert, 2012) to invert full impedance tensors and tipper functions from >30 MT stations for the electrical resistivity structure beneath the caldera. Our preferred model reveals the geometry and electrical properties of (1) the conductive caldera fill, (2) the resistive crystalline basement, and (3) an enigmatic mid-crustal conductor related to magmatic activity that post-dates caldera formation.

  13. Melioidosis Vaccines: A Systematic Review and Appraisal of the Potential to Exploit Biodefense Vaccines for Public Health Purposes

    PubMed Central

    Lubell, Yoel; Koh, Gavin C. K. W.; White, Lisa J.; Day, Nicholas P. J.; Titball, Richard W.

    2012-01-01

    Background Burkholderia pseudomallei is a Category B select agent and the cause of melioidosis. Research funding for vaccine development has largely considered protection within the biothreat context, but the resulting vaccines could be applicable to populations who are at risk of naturally acquired melioidosis. Here, we discuss target populations for vaccination, consider the cost-benefit of different vaccination strategies and review potential vaccine candidates. Methods and Findings Melioidosis is highly endemic in Thailand and northern Australia, where a biodefense vaccine might be adopted for public health purposes. A cost-effectiveness analysis model was developed, which showed that a vaccine could be a cost-effective intervention in Thailand, particularly if used in high-risk populations such as diabetics. Cost-effectiveness was observed in a model in which only partial immunity was assumed. The review systematically summarized all melioidosis vaccine candidates and studies in animal models that had evaluated their protectiveness. Possible candidates included live attenuated, whole cell killed, sub-unit, plasmid DNA and dendritic cell vaccines. Live attenuated vaccines were not considered favorably because of possible reversion to virulence and hypothetical risk of latent infection, while the other candidates need further development and evaluation. Melioidosis is acquired by skin inoculation, inhalation and ingestion, but routes of animal inoculation in most published studies to date do not reflect all of this. We found a lack of studies using diabetic models, which will be central to any evaluation of a melioidosis vaccine for natural infection since diabetes is the most important risk factor. Conclusion Vaccines could represent one strand of a public health initiative to reduce the global incidence of melioidosis. PMID:22303489

  14. Metabolic and Homeostatic Changes in Seizures and Acquired Epilepsy—Mitochondria, Calcium Dynamics and Reactive Oxygen Species

    PubMed Central

    Kovac, Stjepana; Dinkova Kostova, Albena T.; Melzer, Nico; Meuth, Sven G.; Gorji, Ali

    2017-01-01

    Acquired epilepsies can arise as a consequence of brain injury and result in unprovoked seizures that emerge after a latent period of epileptogenesis. These epilepsies pose a major challenge to clinicians as they are present in the majority of patients seen in a common outpatient epilepsy clinic and are prone to pharmacoresistance, highlighting an unmet need for new treatment strategies. Metabolic and homeostatic changes are closely linked to seizures and epilepsy, although, surprisingly, no potential treatment targets to date have been translated into clinical practice. We summarize here the current knowledge about metabolic and homeostatic changes in seizures and acquired epilepsy, maintaining a particular focus on mitochondria, calcium dynamics, reactive oxygen species and key regulators of cellular metabolism such as the Nrf2 pathway. Finally, we highlight research gaps that will need to be addressed in the future which may help to translate these findings into clinical practice. PMID:28885567

  15. Microdosing and drug development: past, present and future

    PubMed Central

    Lappin, Graham; Noveck, Robert; Burt, Tal

    2015-01-01

    Introduction Microdosing is an approach to early drug development where exploratory pharmacokinetic data are acquired in humans using inherently safe sub-pharmacologic doses of drug. The first publication of microdose data was 10 years ago and this review comprehensively explores the microdose concept from conception, over the past decade, up until the current date. Areas covered The authors define and distinguish the concept of microdosing from similar approaches. The authors review the ability of microdosing to provide exploratory pharmacokinetics (concentration-time data) but exclude microdosing using positron emission tomography. The article provides a comprehensive review of data within the peer-reviewed literature as well as the latest applications and a look into the future, towards where microdosing may be headed. Expert opinion Evidence so far suggests that microdosing may be a better predictive tool of human pharmacokinetics than alternative methods and combination with physiologically based modelling may lead to much more reliable predictions in the future. The concept has also been applied to drug-drug interactions, polymorphism and assessing drug concentrations over time at its site of action. Microdosing may yet have more to offer in unanticipated directions and provide benefits that have not been fully realised to date. PMID:23550938

  16. 43 CFR 2545.1 - Qualifications of applicants.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... good faith and in peaceful, adverse possession since the date of issuance of said patent adjoining... under the Act of 1925, a person must either (1) be the owner in good faith of land, acquired prior to... public lands or (2) be a citizen of the United States who, in good faith under color of title or claiming...

  17. 43 CFR 2545.1 - Qualifications of applicants.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... good faith and in peaceful, adverse possession since the date of issuance of said patent adjoining... under the Act of 1925, a person must either (1) be the owner in good faith of land, acquired prior to... public lands or (2) be a citizen of the United States who, in good faith under color of title or claiming...

  18. 43 CFR 2545.1 - Qualifications of applicants.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... good faith and in peaceful, adverse possession since the date of issuance of said patent adjoining... under the Act of 1925, a person must either (1) be the owner in good faith of land, acquired prior to... public lands or (2) be a citizen of the United States who, in good faith under color of title or claiming...

  19. 23 CFR 710.603 - Direct Federal acquisition.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the STD to commence right-of-way acquisition, the date of the project agreement and a statement that... negotiations which have been conducted by the STD with landowners; (9) An agreement that the STD will pay its... required by State law any time before the FHWA makes a determination that the STD is unable to acquire the...

  20. 23 CFR 710.603 - Direct Federal acquisition.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the STD to commence right-of-way acquisition, the date of the project agreement and a statement that... negotiations which have been conducted by the STD with landowners; (9) An agreement that the STD will pay its... required by State law any time before the FHWA makes a determination that the STD is unable to acquire the...

  1. 23 CFR 710.603 - Direct Federal acquisition.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the STD to commence right-of-way acquisition, the date of the project agreement and a statement that... negotiations which have been conducted by the STD with landowners; (9) An agreement that the STD will pay its... required by State law any time before the FHWA makes a determination that the STD is unable to acquire the...

  2. 78 FR 34408 - Notice of Applications for Deregistration Under Section 8(f) of the Investment Company Act of 1940

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ... reorganization were paid by Stadion Money Management, LLC, investment adviser to the acquiring fund. Filing Date... Investment Management, Exemptive Applications Office, 100 F Street NE., Washington, DC 20549-8010... Money Market [File No. 811-2910] Madison Mosaic Tax-Free Trust [File No. 811-3486] Madison Mosaic Income...

  3. 26 CFR 1.358-2 - Allocation of basis among nonrecognition property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... respect of shares of stock or securities that were acquired on the same date and at the same price. To the... different prices, the share of stock or security received shall be divided into segments based on the... different prices exchanges such shares of stock or securities under the terms of section 354, 355, or 356...

  4. 76 FR 47278 - Notice of Applications for Deregistration Under Section 8(f) of the Investment Company Act of 1940

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ... Investment Management, Office of Investment Company Regulation, 100 F Street, NE., Washington, DC 20549-8010... Management, Inc., investment adviser to the acquiring fund. Filing Date: The application was filed on July 8... incurred in connection with the liquidation were paid by applicant and Pioneer Investment Management, Inc...

  5. LANDSAT 3 world standard catalog, 6 March - 31 July 1978

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The World Standard Catalog lists imagery acquired by LANDSAT 3 which was processed and input to the data files during the referenced period. Information such as date of entry, cloud cover, and image quality is given for each scene. The microfilm roll and frame on which the scene may be found is also indicated.

  6. How to Identify a Domain-General Learning Mechanism when You See One

    ERIC Educational Resources Information Center

    Rakison, David H.; Yermolayeva, Yevdokiya

    2011-01-01

    A longstanding and fundamental debate in developmental science is whether knowledge is acquired through domain-specific or domain-general mechanisms. To date, there exists no tool to determine whether experimental data support one theoretical approach or the other. In this article, we argue that the U- and N-shaped curves found in a number of…

  7. 76 FR 14588 - Defense Federal Acquisition Regulation Supplement; Nonavailability Exception for Procurement of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-17

    ... Defense Authorization Act for Fiscal Year 2011. Section 847 provides a nonavailability exception to the requirement at 10 U.S.C. 2533a (Berry Amendment) to acquire only domestic hand or measuring tools. DATES... DFARS 225.7002-2 to implement section 847 of the National Defense Authorization Act for Fiscal Year 2011...

  8. 36 CFR 223.193 - Procedures for reporting acquisition and disposition of unprocessed Federal timber.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... transfer, provide to such other person a written notice of origin, species, estimated volume or actual..., from whom the timber was acquired; the date of acquisition; the origin of National Forest System timber... disposal; (2) An accounting by origin, in net board feet Scribner or cubic feet, of the volume of National...

  9. 36 CFR 223.193 - Procedures for reporting acquisition and disposition of unprocessed Federal timber.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... transfer, provide to such other person a written notice of origin, species, estimated volume or actual..., from whom the timber was acquired; the date of acquisition; the origin of National Forest System timber... disposal; (2) An accounting by origin, in net board feet Scribner or cubic feet, of the volume of National...

  10. 36 CFR 223.193 - Procedures for reporting acquisition and disposition of unprocessed Federal timber.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... transfer, provide to such other person a written notice of origin, species, estimated volume or actual..., from whom the timber was acquired; the date of acquisition; the origin of National Forest System timber... disposal; (2) An accounting by origin, in net board feet Scribner or cubic feet, of the volume of National...

  11. 36 CFR 223.193 - Procedures for reporting acquisition and disposition of unprocessed Federal timber.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... transfer, provide to such other person a written notice of origin, species, estimated volume or actual..., from whom the timber was acquired; the date of acquisition; the origin of National Forest System timber... disposal; (2) An accounting by origin, in net board feet Scribner or cubic feet, of the volume of National...

  12. 5 CFR 410.307 - Training for promotion or placement in other positions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... capability to learn skills and acquire knowledge and abilities needed in the new position; and (C) The... displaced or surplus employees covered by this part. Effective Date Note: At 75 FR 67605, Nov. 3, 2010....602” and adding in its place the phrase, “5 CFR part 330, subpart F”, effective Mar. 3, 2011. ...

  13. Department of Defense Healthcare Management System Modernization (DHMSM)

    DTIC Science & Technology

    2016-03-01

    2016 Major Automated Information System Annual Report Department of Defense Healthcare Management System Modernization (DHMSM) Defense...DSN Fax: Date Assigned: November 16, 2015 Program Information Program Name Department of Defense Healthcare Management System Modernization...DHMSM) DoD Component DoD The acquiring DoD Component is Program Executive Office (PEO) Department of Defense (DoD) Healthcare Management Systems (DHMS

  14. 26 CFR 1.381(c)(14)-1 - Dividend carryover to personal holding company.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... income for the second preceding taxable year is $12,000, the sum of $2,000 (separate excess from N... $12,000 Dividends paid deduction of N Corporation for first preceding taxable year $50,000 Taxable... section 561 for taxable years ending after the date of distribution or transfer for which the acquiring...

  15. Identifying the Trends and Impact of Graduate Attributes on Employability: A Literature Review

    ERIC Educational Resources Information Center

    Osmani, Mohamad; Weerakkody, Vishanth; Hindi, Nitham M.; Al-Esmail, Rajab; Eldabi, Tillal; Kapoor, Kawaljeet; Irani, Zahir

    2015-01-01

    Graduate employability has become an issue since there are broad mismatches between the acquired graduate skills from university and the required skills by employers. While previous researches have outlined the salient skills that need to be embedded in graduate education, to date no studies have attempted to methodically identify and synthesize…

  16. 77 FR 68122 - Formations of, Acquisitions by, and Mergers of Savings and Loan Holding Companies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ..., Minneapolis, Minnesota 55480-0291: 1. The Miller Family 2012 Trust U/A Dated December 21, 2012, St. Cloud... Services of Saint Cloud, Inc., Saint Cloud, MN, and thereby indirectly acquire control of Liberty Savings Bank, FSB, Saint Cloud, Minnesota. Board of Governors of the Federal Reserve System, November 9, 2012...

  17. 26 CFR 1.597-5 - Taxable Transfers.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... pursuant to an election under § 1.597-4(g)); or (iii) Issues stock such that the stock that was outstanding...) Basis limited to fair market value. If all of the stock of the corporation is not acquired on the date... acquisitions are provided in paragraph (e) of this section. (b) Deemed asset acquisitions upon stock purchase...

  18. Entering Adulthood: Preventing Sexually Related Disease. A Curriculum for Grades 9-12. Contemporary Health Series.

    ERIC Educational Resources Information Center

    Hubbard, Betty M.

    This book provides detailed up-to-date information about sexually transmitted diseases (STDs), including Acquired Immune Deficiency Syndrome (AIDS), chlamydia, herpes, syphilis, genital warts, and gonorrhea. Designed to help students make choices that eliminate or reduce the risk of contracting an STD, this module gives high school teachers six…

  19. 26 CFR 1.44-4 - Recapture for certain dispositions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... within 36 months after the date on which he acquired it (or, in the case of construction by the taxpayer... months in the case of acquisition by purchase and 2 years in the case of construction by the taxpayer provided, however, that such construction has commenced within the 18-month period. Thus, a calendar-year...

  20. 26 CFR 1.44-4 - Recapture for certain dispositions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... within 36 months after the date on which he acquired it (or, in the case of construction by the taxpayer... months in the case of acquisition by purchase and 2 years in the case of construction by the taxpayer provided, however, that such construction has commenced within the 18-month period. Thus, a calendar-year...

  1. Districts Take Action to Stem Violence Aimed at Teachers

    ERIC Educational Resources Information Center

    Honawar, Vaishali

    2008-01-01

    Experts caution that reliable and up-to-date statistics on student violence against teachers can be hard to acquire. National and district data, however, show a drop in such violence over the past decade. The National Center for Education Statistics' 2007 school crime and safety report, the only known source for such data nationwide, says the…

  2. Evaluation of the new radiation belt AE9/AP9/SPM model for a cislunar mission

    NASA Astrophysics Data System (ADS)

    Badavi, Francis F.; Walker, Steven A.; Santos Koos, Lindsey M.

    2014-09-01

    Space mission planners continue to experience challenges associated with human space flight. Concerned with the omnipresence of harmful ionizing radiation in space, at the mission design stage, mission planners must evaluate the amount of exposure the crew of a spacecraft is subjected to during the transit trajectory from low Earth orbit (LEO) to geosynchronous orbit (GEO) and beyond (free space). The Earth's geomagnetic field is located within the domain of LEO-GEO and, depending on latitude, extends out some 40,000-60,000 km. This field contains the Van Allen trapped electrons, protons, and low-energy plasmas, such as the nuclei of hydrogen, helium, oxygen, and to a lesser degree other atoms. In addition, there exist the geomagnetically attenuated energetic galactic cosmic rays (GCR). These particles are potentially harmful to improperly shielded crew members and onboard subsystems. Mitigation strategies to limit the exposure due to free space GCR and sporadic solar energetic particles (SEP) such as flare and coronal mass ejection (CME) must also be exercised beyond the trapped field. Presented in this work is the exposure analysis for a multi-vehicle mission planned for the epoch of February 2020 from LEO to the Earth-moon Lagrange-point two (L2), located approximately 63,000 km beyond the orbit of the Earth-moon binary system. Space operation at L2 provides a gravitationally stable orbit for a vehicle and partially eliminates the need for periodic thrust-vectoring to maintain orbital stability. In the cislunar (Earth-moon) space of L2, the mission trajectory and timeline in this work call for a cargo vehicle to rendezvous with a crew vehicle. This is followed by 15 days of space activities at L2 while the cargo and crew vehicles are docked after which the crew returns to Earth. The mission epoch of 2020 is specifically chosen as it is anticipated that the next solar minimum (i.e. end of cycle 24) in the Sun's approximate 11 years cycle will take place around this time. From a mission planning point of view, this date is ideal as the predictable GCR exposure will be at a maximum, while the sporadic SEP will be at a minimum. In addition, it is anticipated that by 2020 a vehicle capable of launching a crew of four will be operationally ready. During the LEO-GEO transit, the crew and cargo vehicles will encounter exposure from trapped particles and attenuated GCR, followed by free space exposure due to GCR and SEP during solar active times. Within the trapped field, a challenge arises from properly calculating the amount of exposure acquired. Within this field, in the absence of SEP (i.e. solar quiet times), the vehicles will have to transit through an inner proton belt, an inner and outer electron belts, and an attenuated GCR field. There exist a number of models to define the intensities of the trapped particles during the quiet and active SEP. Among the more established trapped models are the historic and popular electron/proton AE8/AP8 model dating back to the 1980s, the historic and less popular electron/proton CRRES model dating back to 1990s, and the recently released electron/proton/space plasma AE9/AP9/SPM model. The AE9/AP9/SPM model is a major improvement over the older AE8/AP8 and CRRES models. This model is derived from numerous measurements acquired over four solar cycles dating back to the 1970s, roughly representing 40 years of data collection. In contrast, the older AE8/AP8 and CRRES models were limited to only a few months of measurements taken during the prior solar minima and maxima. In this work, within the trapped field, along the design trajectory of the crew vehicle, the AE9/AP9/SPM model is evaluated against the older AE8/AP8 model during solar quiet times. The analysis is then extended to the GCR dominated en-route, cislunar L2 space and return trajectories in order to provide cumulative exposure estimates to the crew vehicle for the duration of the entire mission.

  3. The dust environment of comet 67P/Churyumov-Gerasimenko: results from Monte Carlo dust tail modelling applied to a large ground-based observation data set

    NASA Astrophysics Data System (ADS)

    Moreno, Fernando; Muñoz, Olga; Gutiérrez, Pedro J.; Lara, Luisa M.; Snodgrass, Colin; Lin, Zhong Y.; Della Corte, Vincenzo; Rotundi, Alessandra; Yagi, Masafumi

    2017-07-01

    We present an extensive data set of ground-based observations and models of the dust environment of comet 67P/Churyumov-Gerasimenko covering a large portion of the orbital arc from about 4.5 au pre-perihelion through 3.0 au post-perihelion, acquired during the current orbit. In addition, we have also applied the model to a dust trail image acquired during this orbit, as well as to dust trail observations obtained during previous orbits, in both the visible and the infrared. The results of the Monte Carlo modelling of the dust tail and trail data are generally consistent with the in situ results reported so far by the Rosetta instruments Optical, Spectroscopic, and Infrared Remote Imaging System (OSIRIS) and Grain Impact Analyser and Dust Accumulator (GIADA). We found the comet nucleus already active at 4.5 au pre-perihelion, with a dust production rate increasing up to ˜3000 kg s-1 some 20 d after perihelion passage. The dust size distribution at sizes smaller than r = 1 mm is linked to the nucleus seasons, being described by a power law of index -3.0 during the comet nucleus southern hemisphere winter but becoming considerably steeper, with values between -3.6 and -4.3, during the nucleus southern hemisphere summer, which includes perihelion passage (from about 1.7 au inbound to 2.4 au outbound). This agrees with the increase of the steepness of the dust size distribution found from GIADA measurements at perihelion showing a power index of -3.7. The size distribution at sizes larger than 1 mm for the current orbit is set to a power law of index -3.6, which is near the average value of insitu measurements by OSIRIS on large particles. However, in order to fit the trail data acquired during past orbits previous to the 2009 perihelion passage, a steeper power-law index of -4.1 has been set at those dates, in agreement with previous trail modelling. The particle sizes are set at a minimum of r = 10 μm, and a maximum size, which increases with decreasing heliocentric distance, in the 1-40 cm radius domain. The particle terminal velocities are found to be consistent with the in situ measurements as derived from the instrument GIADA on board Rosetta.

  4. A new aircraft hurricane wind climatology and applications in assessing the predictive skill of tropical cyclone intensity using high-resolution ensemble forecasts

    NASA Astrophysics Data System (ADS)

    Judt, Falko; Chen, Shuyi S.

    2015-07-01

    Hurricane surface wind is a key measure of storm intensity. However, a climatology of hurricane winds is lacking to date, largely because hurricanes are relatively rare events and difficult to observe over the open ocean. Here we present a new hurricane wind climatology based on objective surface wind analyses, which are derived from Stepped Frequency Microwave Radiometer measurements acquired by NOAA WP-3D and U.S. Air Force WC-130J hurricane hunter aircraft. The wind data were collected during 72 aircraft reconnaissance missions into 21 western Atlantic hurricanes from 1998 to 2012. This climatology provides an opportunity to validate hurricane intensity forecasts beyond the simplistic maximum wind speed metric and allows evaluating the predictive skill of probabilistic hurricane intensity forecasts using high-resolution model ensembles. An example of application is presented here using a 1.3 km grid spacing Weather Research and Forecasting model ensemble forecast of Hurricane Earl (2010).

  5. Case report: acquisition of three spoken languages by a child with a cochlear implant.

    PubMed

    Francis, Alexander L; Ho, Diana Wai Lam

    2003-03-01

    There have been only two reports of multilingual cochlear implant users to date, and both of these were postlingually deafened adults. Here we report the case of a 6-year-old early-deafened child who is acquiring Cantonese, English and Mandarin in Hong Kong. He and two age-matched peers with similar educational backgrounds were tested using common, standardized tests of vocabulary and expressive and receptive language skills (Peabody Picture Vocabulary Test (Revised) and Reynell Developmental Language Scales version II). Results show that this child is acquiring Cantonese, English and Mandarin to a degree comparable to two classmates with normal hearing and similar educational and social backgrounds.

  6. Zebrafish Models of Human Leukemia: Technological Advances and Mechanistic Insights.

    PubMed

    Harrison, Nicholas R; Laroche, Fabrice J F; Gutierrez, Alejandro; Feng, Hui

    2016-01-01

    Insights concerning leukemic pathophysiology have been acquired in various animal models and further efforts to understand the mechanisms underlying leukemic treatment resistance and disease relapse promise to improve therapeutic strategies. The zebrafish (Danio rerio) is a vertebrate organism with a conserved hematopoietic program and unique experimental strengths suiting it for the investigation of human leukemia. Recent technological advances in zebrafish research including efficient transgenesis, precise genome editing, and straightforward transplantation techniques have led to the generation of a number of leukemia models. The transparency of the zebrafish when coupled with improved lineage-tracing and imaging techniques has revealed exquisite details of leukemic initiation, progression, and regression. With these advantages, the zebrafish represents a unique experimental system for leukemic research and additionally, advances in zebrafish-based high-throughput drug screening promise to hasten the discovery of novel leukemia therapeutics. To date, investigators have accumulated knowledge of the genetic underpinnings critical to leukemic transformation and treatment resistance and without doubt, zebrafish are rapidly expanding our understanding of disease mechanisms and helping to shape therapeutic strategies for improved outcomes in leukemic patients.

  7. Zebrafish Models of Human Leukemia: Technological Advances and Mechanistic Insights

    PubMed Central

    Harrison, Nicholas R.; Laroche, Fabrice J.F.; Gutierrez, Alejandro

    2016-01-01

    Insights concerning leukemic pathophysiology have been acquired in various animal models and further efforts to understand the mechanisms underlying leukemic treatment resistance and disease relapse promise to improve therapeutic strategies. The zebrafish (Danio rerio) is a vertebrate organism with a conserved hematopoietic program and unique experimental strengths suiting it for the investigation of human leukemia. Recent technological advances in zebrafish research including efficient transgenesis, precise genome editing, and straightforward transplantation techniques have led to the generation of a number of leukemia models. The transparency of the zebrafish when coupled with improved lineage-tracing and imaging techniques has revealed exquisite details of leukemic initiation, progression, and regression. With these advantages, the zebrafish represents a unique experimental system for leukemic research and additionally, advances in zebrafish-based high-throughput drug screening promise to hasten the discovery of novel leukemia therapeutics. To date, investigators have accumulated knowledge of the genetic underpinnings critical to leukemic transformation and treatment resistance and without doubt, zebrafish are rapidly expanding our understanding of disease mechanisms and helping to shape therapeutic strategies for improved outcomes in leukemic patients. PMID:27165361

  8. A geospatial database model for the management of remote sensing datasets at multiple spectral, spatial, and temporal scales

    NASA Astrophysics Data System (ADS)

    Ifimov, Gabriela; Pigeau, Grace; Arroyo-Mora, J. Pablo; Soffer, Raymond; Leblanc, George

    2017-10-01

    In this study the development and implementation of a geospatial database model for the management of multiscale datasets encompassing airborne imagery and associated metadata is presented. To develop the multi-source geospatial database we have used a Relational Database Management System (RDBMS) on a Structure Query Language (SQL) server which was then integrated into ArcGIS and implemented as a geodatabase. The acquired datasets were compiled, standardized, and integrated into the RDBMS, where logical associations between different types of information were linked (e.g. location, date, and instrument). Airborne data, at different processing levels (digital numbers through geocorrected reflectance), were implemented in the geospatial database where the datasets are linked spatially and temporally. An example dataset consisting of airborne hyperspectral imagery, collected for inter and intra-annual vegetation characterization and detection of potential hydrocarbon seepage events over pipeline areas, is presented. Our work provides a model for the management of airborne imagery, which is a challenging aspect of data management in remote sensing, especially when large volumes of data are collected.

  9. Multilingualism and fMRI: Longitudinal Study of Second Language Acquisition

    PubMed Central

    Andrews, Edna; Frigau, Luca; Voyvodic-Casabo, Clara; Voyvodic, James; Wright, John

    2013-01-01

    BOLD fMRI is often used for the study of human language. However, there are still very few attempts to conduct longitudinal fMRI studies in the study of language acquisition by measuring auditory comprehension and reading. The following paper is the first in a series concerning a unique longitudinal study devoted to the analysis of bi- and multilingual subjects who are: (1) already proficient in at least two languages; or (2) are acquiring Russian as a second/third language. The focus of the current analysis is to present data from the auditory sections of a set of three scans acquired from April, 2011 through April, 2012 on a five-person subject pool who are learning Russian during the study. All subjects were scanned using the same protocol for auditory comprehension on the same General Electric LX 3T Signa scanner in Duke University Hospital. Using a multivariate analysis of covariance (MANCOVA) for statistical analysis, proficiency measurements are shown to correlate significantly with scan results in the Russian conditions over time. The importance of both the left and right hemispheres in language processing is discussed. Special attention is devoted to the importance of contextualizing imaging data with corresponding behavioral and empirical testing data using a multivariate analysis of variance. This is the only study to date that includes: (1) longitudinal fMRI data with subject-based proficiency and behavioral data acquired in the same time frame; and (2) statistical modeling that demonstrates the importance of covariate language proficiency data for understanding imaging results of language acquisition. PMID:24961428

  10. Multilingualism and fMRI: Longitudinal Study of Second Language Acquisition.

    PubMed

    Andrews, Edna; Frigau, Luca; Voyvodic-Casabo, Clara; Voyvodic, James; Wright, John

    2013-05-28

    BOLD fMRI is often used for the study of human language. However, there are still very few attempts to conduct longitudinal fMRI studies in the study of language acquisition by measuring auditory comprehension and reading. The following paper is the first in a series concerning a unique longitudinal study devoted to the analysis of bi- and multilingual subjects who are: (1) already proficient in at least two languages; or (2) are acquiring Russian as a second/third language. The focus of the current analysis is to present data from the auditory sections of a set of three scans acquired from April, 2011 through April, 2012 on a five-person subject pool who are learning Russian during the study. All subjects were scanned using the same protocol for auditory comprehension on the same General Electric LX 3T Signa scanner in Duke University Hospital. Using a multivariate analysis of covariance (MANCOVA) for statistical analysis, proficiency measurements are shown to correlate significantly with scan results in the Russian conditions over time. The importance of both the left and right hemispheres in language processing is discussed. Special attention is devoted to the importance of contextualizing imaging data with corresponding behavioral and empirical testing data using a multivariate analysis of variance. This is the only study to date that includes: (1) longitudinal fMRI data with subject-based proficiency and behavioral data acquired in the same time frame; and (2) statistical modeling that demonstrates the importance of covariate language proficiency data for understanding imaging results of language acquisition.

  11. An assessment of the relationship between the World Health Organization HIV drug resistance early warning indicators and HIV drug resistance acquisition.

    PubMed

    St-Jean, M; Harrigan, P R; Sereda, P; Montaner, Jsg; Lima, V D

    2017-05-01

    The World Health Organization (WHO)'s HIV drug resistance (HIVDR) early warning indicators (EWIs) measure antiretroviral therapy (ART)-site factors associated with HIVDR prevention, without HIVDR laboratory testing. We assessed the relationship between EWIs and HIVDR acquisition using data from British Columbia, Canada. Eligible patients were ART-naïve, were ≥ 19 years old, had initiated ART between 1 January 2000 and 31 December 2012, had ≥ 15 months of follow-up, and were without transmitted HIVDR. Patients were followed for acquired HIVDR until 31 March 2014, the last contact date, or death. We built logistic regression models to assess the associations and predictive ability of individual indicators and of the EWI Score (the number of indicators for which a patient did not meet the criteria) on HIVDR acquisition (to any class of HIVDR, lamivudine (3TC)/emtricitabine (FTC), nonnucleoside reverse transcriptase inhibitors (NNRTIs), nucleoside reverse transcriptase inhibitors (NRTIs) or protease inhibitors (PIs)]). All explored EWIs were associated with at least one class of HIVDR, with the exception of 'ART prescribing practices'. We observed a dose-response relationship between acquiring HIVDR to any antiretroviral class and an increasing EWI score in our predictive logistic regression model. The area under the curve was 0.848 (excellent discrimination). The adjusted odds ratios for acquiring any class of HIVDR for an EWI score of 1, 2 and ≥ 3 versus 0 were 2.30 [95% confidence Interval (CI) 1.21-4.38], 3.35 (95% CI: 1.86-6.03) and 7.26 (95% CI: 4.18-12.61), respectively. Several EWIs were associated with and predictive of HIVDR, supporting the WHO EWIs as a component of the HIVDR prevention method in settings where HIVDR testing is not routinely or widely available. © 2016 British HIV Association.

  12. The Circumstellar Environment of Low Mass Star Forming Regions

    NASA Technical Reports Server (NTRS)

    Butner, Harold M.

    1999-01-01

    The final technical report of the NASA grant project is presented. The goals of the grant were to: (1) analyze the data from the Far-Infrared (FIR) Camera on board the Kuiper Airborne Observatory (KAO); (2) acquire additional data at other wavelengths for models and (4) to develop source models for the Young stellar objects (YSOs)under study. The complete Spectral Energy Distribution (SED) from 10 microns out to 1.3 mm for all sources being studied have been obtained. The FIR imaging data was processed to reveal the maximum angular resolution possible, which allows us to model the disk. To model the disk we have the high resolution millimeter interferometry data. In summary the results to date are: (1) the vast majority of embedded YSOs in Taurus are compact at 100 microns. The models mos consistent with our data and other observations are either dominated by disk emissions, or envelopes that have relatively steep density gradients; (2) the submillimeter/millimeter photometer suggests that models are very successful. Disk emission plays an important role and must be considered when predicting the overall emission. (3) in the two cases, where we seem to have extended emission, we have to investigate other possible source models than a Shu collapse.

  13. A slide down a slippery slope: ethical guidelines in the dissemination of computer-based presentations

    Treesearch

    Patrick C. Tobin; James L. Frazier

    2009-01-01

    The continual development of technology opens many new and exciting doors in all walks of life, including science. Undoubtedly, we all have benefited from the ability to rapidly disseminate and acquire scientific information. Published articles can be downloaded from the Internet even prior to their "actual" publication date, requests for pdf reprints of...

  14. Crossroads: A K-16 American History Curriculum. The High School Curriculum. [Part Four.

    ERIC Educational Resources Information Center

    Council for Citizenship Education, Troy, NY.

    This U.S. history curriculum guide, based upon the historical essays written by Richard B. Bernstein, is intended for students in grades 9 - 12 and refines and extends the understanding of U.S. history that students have acquired to date. Students are challenged to venture into historical explorations and analyses in order to compare and contrast…

  15. 75 FR 20859 - Notice of Realty Action, Independence National Historical Park, Pennsylvania and Valley Forge...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ... County, Pennsylvania. The United States will convey fee simple title to INDE Tract 01-182 by virtue of a... described in paragraph I above, the United States will acquire fee simple title to the surface and mineral... require. For a period of 45 days from the date of this notice, interested parties may submit written...

  16. Teacher Certification Renewal System: An Analysis Based on a Nation-Wide Survey of Japanese Teachers of English

    ERIC Educational Resources Information Center

    Nakayama, Natsue; Takagi, Akiko; Imamura, Hiromi

    2010-01-01

    In October 2007, three education bills, including the Revised Teacher's License Law were approved by the Central Education Council in February and submitted to the Diet. The purpose of the Revised Teacher's License Law was "to ensure teachers systematically acquire up-to-date knowledge and skills to maintain the professional competencies…

  17. 12 CFR Appendix B to Subpart G - Illustrative Written Source Documents for Higher-Priced Mortgage Loan Appraisal Rules

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... title commitment report detailing the seller's ownership of the property, the date it was acquired, or... Higher-Priced Mortgage Loan Appraisal Rules B Appendix B to Subpart G Banks and Banking COMPTROLLER OF...-Priced Mortgage Loans Pt. 34, Subp. G, App. B Appendix B to Subpart G—Illustrative Written Source...

  18. Effect of certain chemical attributes of vegetation on forest inflammability

    Treesearch

    Leon W. Richards

    1940-01-01

    Forest Service administrators and fire-research men have long felt the need of information concerning the effect of vegetation such as shrubs, grasses, and forbs (nongrasslike herbs) on the rate of spread of fires. To date, all knowledge of the subject has been acquired empirically in the field, or deduced from knowledge of fire behavior as influenced by the condition...

  19. Double the dates and go for Bayes - Impacts of model choice, dating density and quality on chronologies

    NASA Astrophysics Data System (ADS)

    Blaauw, Maarten; Christen, J. Andrés; Bennett, K. D.; Reimer, Paula J.

    2018-05-01

    Reliable chronologies are essential for most Quaternary studies, but little is known about how age-depth model choice, as well as dating density and quality, affect the precision and accuracy of chronologies. A meta-analysis suggests that most existing late-Quaternary studies contain fewer than one date per millennium, and provide millennial-scale precision at best. We use existing and simulated sediment cores to estimate what dating density and quality are required to obtain accurate chronologies at a desired precision. For many sites, a doubling in dating density would significantly improve chronologies and thus their value for reconstructing and interpreting past environmental changes. Commonly used classical age-depth models stop becoming more precise after a minimum dating density is reached, but the precision of Bayesian age-depth models which take advantage of chronological ordering continues to improve with more dates. Our simulations show that classical age-depth models severely underestimate uncertainty and are inaccurate at low dating densities, and also perform poorly at high dating densities. On the other hand, Bayesian age-depth models provide more realistic precision estimates, including at low to average dating densities, and are much more robust against dating scatter and outliers. Indeed, Bayesian age-depth models outperform classical ones at all tested dating densities, qualities and time-scales. We recommend that chronologies should be produced using Bayesian age-depth models taking into account chronological ordering and based on a minimum of 2 dates per millennium.

  20. Human origins: Out of Africa

    PubMed Central

    Tattersall, Ian

    2009-01-01

    Our species, Homo sapiens, is highly autapomorphic (uniquely derived) among hominids in the structure of its skull and postcranial skeleton. It is also sharply distinguished from other organisms by its unique symbolic mode of cognition. The fossil and archaeological records combine to show fairly clearly that our physical and cognitive attributes both first appeared in Africa, but at different times. Essentially modern bony conformation was established in that continent by the 200–150 Ka range (a dating in good agreement with dates for the origin of H. sapiens derived from modern molecular diversity). The event concerned was apparently short-term because it is essentially unanticipated in the fossil record. In contrast, the first convincing stirrings of symbolic behavior are not currently detectable until (possibly well) after 100 Ka. The radical reorganization of gene expression that underwrote the distinctive physical appearance of H. sapiens was probably also responsible for the neural substrate that permits symbolic cognition. This exaptively acquired potential lay unexploited until it was “discovered” via a cultural stimulus, plausibly the invention of language. Modern humans appear to have definitively exited Africa to populate the rest of the globe only after both their physical and cognitive peculiarities had been acquired within that continent. PMID:19805256

  1. Immunophenotypic characterization of the cutaneous exanthem of SIV-infected rhesus monkeys. Apposition of degenerative Langerhans cells and cytotoxic lymphocytes during the development of acquired immunodeficiency syndrome.

    PubMed Central

    Ringler, D. J.; Hancock, W. W.; King, N. W.; Letvin, N. L.; Daniel, M. D.; Desrosiers, R. C.; Murphy, G. F.

    1987-01-01

    A T-cell tropic retrovirus, simian immunodeficiency virus (SIV), has recently been isolated from immunodeficient rhesus monkeys. This virus has remarkable similarities to human immunodeficiency virus (HIV), the etiologic agent of acquired immunodeficiency syndrome. Subsequent studies of simian infection with SIV have shown it to be a relevant animal model for studying the pathogenesis of AIDS in man. In both HIV-infected humans and SIV-infected monkeys, a cutaneous maculopapular eruption has been described. To date, the pathogenesis and possible relationship of these exanthema to the evolution of systemic immunosuppression have remained obscure. In this study, the mononuclear cell infiltrates that characterize skin rashes of SIV-infected rhesus monkeys were found to be composed predominantly of cells with phenotypic characteristics of cytotoxic/suppressor (T8+) lymphocytes and natural killer cells. Many of these cells expressed membrane-bound interleukin-2 receptor molecules. Double labeling and immunoelectron microscopy revealed these cells in direct contact with degenerative Langerhans cells within the epidermis and dermis. These observations suggest that the cutaneous rash associated with SIV infection may be the consequence of target cell injury of Langerhans cells by effector cells with cytotoxic potential. Images Figure 1 Figure 2 Figure 3 PMID:3030113

  2. Calibration of Safecast dose rate measurements.

    PubMed

    Cervone, Guido; Hultquist, Carolynne

    2018-10-01

    A methodology is presented to calibrate contributed Safecast dose rate measurements acquired between 2011 and 2016 in the Fukushima prefecture of Japan. The Safecast data are calibrated using observations acquired by the U.S. Department of Energy at the time of the 2011 Fukushima Daiichi power plant nuclear accident. The methodology performs a series of interpolations between the U.S. government and contributed datasets at specific temporal windows and at corresponding spatial locations. The coefficients found for all the different temporal windows are aggregated and interpolated using quadratic regressions to generate a time dependent calibration function. Normal background radiation, decay rates, and missing values are taken into account during the analysis. Results show that the standard Safecast static transformation function overestimates the official measurements because it fails to capture the presence of two different Cesium isotopes and their changing magnitudes with time. A model is created to predict the ratio of the isotopes from the time of the accident through 2020. The proposed time dependent calibration takes into account this Cesium isotopes ratio, and it is shown to reduce the error between U.S. government and contributed data. The proposed calibration is needed through 2020, after which date the errors introduced by ignoring the presence of different isotopes will become negligible. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. Technology and Technique Standards for Camera-Acquired Digital Dermatologic Images: A Systematic Review.

    PubMed

    Quigley, Elizabeth A; Tokay, Barbara A; Jewell, Sarah T; Marchetti, Michael A; Halpern, Allan C

    2015-08-01

    Photographs are invaluable dermatologic diagnostic, management, research, teaching, and documentation tools. Digital Imaging and Communications in Medicine (DICOM) standards exist for many types of digital medical images, but there are no DICOM standards for camera-acquired dermatologic images to date. To identify and describe existing or proposed technology and technique standards for camera-acquired dermatologic images in the scientific literature. Systematic searches of the PubMed, EMBASE, and Cochrane databases were performed in January 2013 using photography and digital imaging, standardization, and medical specialty and medical illustration search terms and augmented by a gray literature search of 14 websites using Google. Two reviewers independently screened titles of 7371 unique publications, followed by 3 sequential full-text reviews, leading to the selection of 49 publications with the most recent (1985-2013) or detailed description of technology or technique standards related to the acquisition or use of images of skin disease (or related conditions). No universally accepted existing technology or technique standards for camera-based digital images in dermatology were identified. Recommendations are summarized for technology imaging standards, including spatial resolution, color resolution, reproduction (magnification) ratios, postacquisition image processing, color calibration, compression, output, archiving and storage, and security during storage and transmission. Recommendations are also summarized for technique imaging standards, including environmental conditions (lighting, background, and camera position), patient pose and standard view sets, and patient consent, privacy, and confidentiality. Proposed standards for specific-use cases in total body photography, teledermatology, and dermoscopy are described. The literature is replete with descriptions of obtaining photographs of skin disease, but universal imaging standards have not been developed, validated, and adopted to date. Dermatologic imaging is evolving without defined standards for camera-acquired images, leading to variable image quality and limited exchangeability. The development and adoption of universal technology and technique standards may first emerge in scenarios when image use is most associated with a defined clinical benefit.

  4. Enabling high-quality observations of surface imperviousness for water runoff modelling from unmanned aerial vehicles

    NASA Astrophysics Data System (ADS)

    Tokarczyk, Piotr; Leitao, Joao Paulo; Rieckermann, Jörg; Schindler, Konrad; Blumensaat, Frank

    2015-04-01

    Modelling rainfall-runoff in urban areas is increasingly applied to support flood risk assessment particularly against the background of a changing climate and an increasing urbanization. These models typically rely on high-quality data for rainfall and surface characteristics of the area. While recent research in urban drainage has been focusing on providing spatially detailed rainfall data, the technological advances in remote sensing that ease the acquisition of detailed land-use information are less prominently discussed within the community. The relevance of such methods increase as in many parts of the globe, accurate land-use information is generally lacking, because detailed image data is unavailable. Modern unmanned air vehicles (UAVs) allow acquiring high-resolution images on a local level at comparably lower cost, performing on-demand repetitive measurements, and obtaining a degree of detail tailored for the purpose of the study. In this study, we investigate for the first time the possibility to derive high-resolution imperviousness maps for urban areas from UAV imagery and to use this information as input for urban drainage models. To do so, an automatic processing pipeline with a modern classification method is tested and applied in a state-of-the-art urban drainage modelling exercise. In a real-life case study in the area of Lucerne, Switzerland, we compare imperviousness maps generated from a consumer micro-UAV and standard large-format aerial images acquired by the Swiss national mapping agency (swisstopo). After assessing their correctness, we perform an end-to-end comparison, in which they are used as an input for an urban drainage model. Then, we evaluate the influence which different image data sources and their processing methods have on hydrological and hydraulic model performance. We analyze the surface runoff of the 307 individual sub-catchments regarding relevant attributes, such as peak runoff and volume. Finally, we evaluate the model's channel flow prediction performance through a cross-comparison with reference flow measured at the catchment outlet. We show that imperviousness maps generated using UAV imagery processed with modern classification methods achieve accuracy comparable with standard, off-the-shelf aerial imagery. In the examined case study, we find that the different imperviousness maps only have a limited influence on modelled surface runoff and pipe flows. We conclude that UAV imagery represents a valuable alternative data source for urban drainage model applications due to the possibility to flexibly acquire up-to-date aerial images at a superior quality and a competitive price. Our analyses furthermore suggest that spatially more detailed urban drainage models can even better benefit from the full detail of UAV imagery.

  5. High-quality observation of surface imperviousness for urban runoff modelling using UAV imagery

    NASA Astrophysics Data System (ADS)

    Tokarczyk, P.; Leitao, J. P.; Rieckermann, J.; Schindler, K.; Blumensaat, F.

    2015-01-01

    Modelling rainfall-runoff in urban areas is increasingly applied to support flood risk assessment particularly against the background of a changing climate and an increasing urbanization. These models typically rely on high-quality data for rainfall and surface characteristics of the area. While recent research in urban drainage has been focusing on providing spatially detailed rainfall data, the technological advances in remote sensing that ease the acquisition of detailed land-use information are less prominently discussed within the community. The relevance of such methods increase as in many parts of the globe, accurate land-use information is generally lacking, because detailed image data is unavailable. Modern unmanned air vehicles (UAVs) allow acquiring high-resolution images on a local level at comparably lower cost, performing on-demand repetitive measurements, and obtaining a degree of detail tailored for the purpose of the study. In this study, we investigate for the first time the possibility to derive high-resolution imperviousness maps for urban areas from UAV imagery and to use this information as input for urban drainage models. To do so, an automatic processing pipeline with a modern classification method is tested and applied in a state-of-the-art urban drainage modelling exercise. In a real-life case study in the area of Lucerne, Switzerland, we compare imperviousness maps generated from a consumer micro-UAV and standard large-format aerial images acquired by the Swiss national mapping agency (swisstopo). After assessing their correctness, we perform an end-to-end comparison, in which they are used as an input for an urban drainage model. Then, we evaluate the influence which different image data sources and their processing methods have on hydrological and hydraulic model performance. We analyze the surface runoff of the 307 individual subcatchments regarding relevant attributes, such as peak runoff and volume. Finally, we evaluate the model's channel flow prediction performance through a cross-comparison with reference flow measured at the catchment outlet. We show that imperviousness maps generated using UAV imagery processed with modern classification methods achieve accuracy comparable with standard, off-the-shelf aerial imagery. In the examined case study, we find that the different imperviousness maps only have a limited influence on modelled surface runoff and pipe flows. We conclude that UAV imagery represents a valuable alternative data source for urban drainage model applications due to the possibility to flexibly acquire up-to-date aerial images at a superior quality and a competitive price. Our analyses furthermore suggest that spatially more detailed urban drainage models can even better benefit from the full detail of UAV imagery.

  6. Transient surface liquid in Titan's south polar region from Cassini

    USGS Publications Warehouse

    Hayes, A.G.; Aharonson, O.; Lunine, J.I.; Kirk, R.L.; Zebker, H.A.; Wye, L.C.; Lorenz, R.D.; Turtle, E.P.; Paillou, P.; Mitri, Giuseppe; Wall, S.D.; Stofan, E.R.; Mitchell, K.L.; Elachi, C.

    2011-01-01

    Cassini RADAR images of Titan's south polar region acquired during southern summer contain lake features which disappear between observations. These features show a tenfold increases in backscatter cross-section between images acquired one year apart, which is inconsistent with common scattering models without invoking temporal variability. The morphologic boundaries are transient, further supporting changes in lake level. These observations are consistent with the exposure of diffusely scattering lakebeds that were previously hidden by an attenuating liquid medium. We use a two-layer model to explain backscatter variations and estimate a drop in liquid depth of approximately 1-m-per-year. On larger scales, we observe shoreline recession between ISS and RADAR images of Ontario Lacus, the largest lake in Titan's south polar region. The recession, occurring between June 2005 and July 2009, is inversely proportional to slopes estimated from altimetric profiles and the exponential decay of near-shore backscatter, consistent with a uniform reduction of 4 ± 1.3 m in lake depth. Of the potential explanations for observed surface changes, we favor evaporation and infiltration. The disappearance of dark features and the recession of Ontario's shoreline represents volatile transport in an active methane-based hydrologic cycle. Observed loss rates are compared and shown to be consistent with available global circulation models. To date, no unambiguous changes in lake level have been observed between repeat images in the north polar region, although further investigation is warranted. These observations constrain volatile flux rates in Titan's hydrologic system and demonstrate that the surface plays an active role in its evolution. Constraining these seasonal changes represents the first step toward our understanding of longer climate cycles that may determine liquid distribution on Titan over orbital time periods.

  7. Effects of management practices on reflectance of spring wheat canopies. [Williston, North Dakota Agricultural Experiment Station

    NASA Technical Reports Server (NTRS)

    Daughtry, C. S. T.; Bauer, M. E.; Crecelius, D. W.; Hixson, M. M. (Principal Investigator)

    1980-01-01

    The effects of available soil moisture, planting date, nitrogen fertilization, and cultivar on reflectance of spring wheat (Triticum aestivum L.) canopies were investigated. Spectral measurements were acquired on eight dates throughout the growing season, along with measurements of crop maturity stage, leaf area index, biomass, plant height, percent soil cover, and soil moisture. Planting date and available soil moisture were the primary agronomic factors which affected reflectance of spring wheat canopies from tillering to maturity. Comparisons of treatments indicated that during the seedling and tillering stages planting date was associated with 36 percent and 85 percent of variation in red and near infrared reflectances, respectively. As the wheat headed and matured, less of the variation in reflectance was associated with planting date and more with available soil moisture. By mid July, soil moisture accounted for 73 percent and 69 percent of the variation in reflectance in red and near infrared bands, respectively. Differences in spectral reflectance among treatments were attributed to changes in leaf area index, biomass, and percent soil cover. Cultivar and N fertilization rate were associated with very little of the variation in the reflectance of these canopies.

  8. Estimation of Extra Length of Stay Attributable to Hospital-Acquired Infections in Adult ICUs Using a Time-Dependent Multistate Model.

    PubMed

    Ohannessian, Robin; Gustin, Marie-Paule; Bénet, Thomas; Gerbier-Colomban, Solweig; Girard, Raphaele; Argaud, Laurent; Rimmelé, Thomas; Guerin, Claude; Bohé, Julien; Piriou, Vincent; Vanhems, Philippe

    2018-04-10

    The objective of the study was to estimate the length of stay of patients with hospital-acquired infections hospitalized in ICUs using a multistate model. Active prospective surveillance of hospital-acquired infection from January 1, 1995, to December 31, 2012. Twelve ICUs at the University of Lyon hospital (France). Adult patients age greater than or equal to 18 years old and hospitalized greater than or equal to 2 days were included in the surveillance. All hospital-acquired infections (pneumonia, bacteremia, and urinary tract infection) occurring during ICU stay were collected. None. The competitive risks of in-hospital death, transfer, or discharge were considered in estimating the change in length of stay due to infection(s), using a multistate model, time of infection onset. Thirty-three thousand four-hundred forty-nine patients were involved, with an overall hospital-acquired infection attack rate of 15.5% (n = 5,176). Mean length of stay was 27.4 (± 18.3) days in patients with hospital-acquired infection and 7.3 (± 7.6) days in patients without hospital-acquired infection. A multistate model-estimated mean found an increase in length of stay by 5.0 days (95% CI, 4.6-5.4 d). The extra length of stay increased with the number of infected site and was higher for patients discharged alive from ICU. No increased length of stay was found for patients presenting late-onset hospital-acquired infection, more than the 25th day after admission. An increase length of stay of 5 days attributable to hospital-acquired infection in the ICU was estimated using a multistate model in a prospective surveillance study in France. The dose-response relationship between the number of hospitalacquired infection and length of stay and the impact of early-stage hospital-acquired infection may strengthen attention for clinicians to focus interventions on early preventions of hospital-acquired infection in ICU.

  9. Relationship between number of sexual intercourse partners and selected health risk behaviors among public high school adolescents.

    PubMed

    Valois, R F; Oeltmann, J E; Waller, J; Hussey, J R

    1999-11-01

    To examine the relationship between number of sexual partners and selected health risk behaviors in a statewide sample of public high school students. The Centers for Disease Control and Prevention Youth Risk Behavior Survey was used to secure usable sexual risk-taking, substance use, and violence/aggression data from 3805 respondents. Because simple polychotomous logistic regression analysis revealed a significant Race x Gender interaction, subsequent multivariate models were constructed separately for each race-gender group. Odds ratios and 95% confidence intervals was calculated from polychotomous logistic regression models for number of sexual intercourse partners and their potential risk behavior correlates. An increased number of sexual intercourse partners were correlated with a cluster of risk behaviors that place adolescents at risk for unintended pregnancy, human immunodeficiency virus/acquired immunodeficiency syndrome, and other sexually transmitted infections. For Black females, alcohol, tobacco, marijuana use, and dating violence behaviors were the strongest predictors of an increased number of sexual partners; white females had similar predictors with the addition of physical fighting. For white males, alcohol, tobacco, marijuana use, physical fighting, carrying weapons, and dating violence were the strongest predictors of an increased number of sexual intercourse partners. Black males had similar predictors with the addition of binge alcohol use. Prevention of adolescent sexual and other health risk behaviors calls for creative approaches in school and community settings and will require long-term intervention strategies focused on adolescent behavior changes and environmental modifications.

  10. Paleomagnetism of the Grenville diabase dyke swarm and implications for the mid Vendian paleolatitude of Laurentia

    NASA Astrophysics Data System (ADS)

    Buchan, K. L.; Ernst, R. E.; Kumarapeli, P. S.

    2004-05-01

    The Vendian-early Cambrian drift of Laurentia is important for theories of `Snowball Earth' and the continental breakup that formed the Iapetus Ocean. However, estimates of Laurentia's paleolatitude in this period differ widely. Some authors have proposed that Laurentia remained in low latitude throughout this period, whereas others have supported rapid drift of the continent from low to high and back to low latitude. To assist in evaluating these models, a paleomagnetic study was conducted on the mid Vendian Grenville dyke swarm of southeastern Laurentia. This 700 km long swarm was emplaced along the Ottawa graben, an aulacogen associated with rifting that preceded the opening of the Iapetus Ocean. The swarm was the subject of an early paleomagnetic study by Murthy (1971). More recently, U-Pb baddeleyite and zircon ages of ca. 590 Ma have been described for three Grenville dykes (Kamo et al. 1995). At one of these sites, on the `Mattawa' dyke, a positive paleomagnetic baked contact test was also reported (Hyodo and Dunlop 1993). In that detailed test thermoremanent overprinting in the zone of hybrid magnetization was shown to match that expected from heat conduction for a cooling dyke. Nevertheless, Hyodo and Dunlop suggested that the steep down remanence in the dyke, although primary, was likely acquired during a geomagnetic excursion because it did not appear to fit the then-available polar wander path. In our study, paleomagnetic sampling was carried out at 36 sites, including all three dated locations. A detailed analysis has been completed for the dated sites and preliminary analysis for the remaining sites. A stable steep down remanence was obtained for all samples in the Mattawa dyke, and in most samples from a second dated site. The third dated site is less stably magnetized and has not yielded a usable remanence direction. Ten additional sites yield stable steep down or occasionally steep up remanences. The presence of a steep remanence in two dated dykes and several others demonstrates that the remanence was not simply acquired during a short-term geomagnetic excursion. The positive baked contact test suggests that it is a primary remanence. If so, this would indicate that Laurentia was at high latitude 590 Ma ago. This would correspond to interpretations of steep magnetizations in the 577 Ma Callander Complex of the Ottawa graben (Symons and Chiasson 1991). However, other dykes in our study do not carry the steep down remanence. Six have an intermediate up WNW magnetization (or its reversal to the SE), suggesting that these dykes may not be 590 Ma in age. The WNW remanence is similar to that reported for the poorly-dated Buckingham volcanics of the Ottawa graben (Dankers and Lapointe 1981). Five additional sites carry other SE directions (both up and down) that are scattered along or near a great circle through the Mattawa and Buckingham volcanic directions, indicating that unresolved overprinting may have smeared the site directions. Therefore, caution should be exercised in interpreting the overall paleomagnetic data set until further U-Pb dating and paleomagnetic analysis have clarified whether more than one age of dyke swarm is present and whether significant overprinting has occurred. References: Dankers and Lapointe, 1981, Can. J. Earth Sci. 18: 1174; Hyodo and Dunlop, 1993, J. Geophys. Res. 98: 7997; Kamo, Krogh, and Kumarapeli, 1995, Can. J. Earth Sci. 32: 273; Murthy, 1971, Can. J. Earth Sci. 8: 802; Symons and Chiasson, 1991, Can. J. Earth Sci. 28: 355.

  11. Honey, Hadza, hunter-gatherers, and human evolution.

    PubMed

    Marlowe, Frank W; Berbesque, J Colette; Wood, Brian; Crittenden, Alyssa; Porter, Claire; Mabulla, Audax

    2014-06-01

    Honey is the most energy dense food in nature. It is therefore not surprising that, where it exists, honey is an important food for almost all hunter-gatherers. Here we describe and analyze widespread honey collecting among foragers and show that where it is absent, in arctic and subarctic habitats, honey bees are also rare to absent. Second, we focus on one hunter-gatherer society, the Hadza of Tanzania. Hadza men and women both rank honey as their favorite food. Hadza acquire seven types of honey. Hadza women usually acquire honey that is close to the ground while men often climb tall baobab trees to raid the largest bee hives with stinging bees. Honey accounts for a substantial proportion of the kilocalories in the Hadza diet, especially that of Hadza men. Cross-cultural forager data reveal that in most hunter-gatherers, men acquire more honey than women but often, as with the Hadza, women do acquire some. Virtually all warm-climate foragers consume honey. Our closest living relatives, the great apes, take honey when they can. We suggest that honey has been part of the diet of our ancestors dating back to at least the earliest hominins. The earliest hominins, however, would have surely been less capable of acquiring as much honey as more recent, fully modern human hunter-gatherers. We discuss reasons for thinking our early ancestors would have acquired less honey than foragers ethnographically described, yet still significantly more than our great ape relatives. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Demic and cultural diffusion propagated the Neolithic transition across different regions of Europe

    PubMed Central

    Fort, Joaquim

    2015-01-01

    The Neolithic transition is the shift from hunting–gathering into farming. About 9000 years ago, the Neolithic transition began to spread from the Near East into Europe, until it reached Northern Europe about 5500 years ago. There are two main models of this spread. The demic model assumes that it was mainly due to the reproduction and dispersal of farmers. The cultural model assumes that European hunter–gatherers become farmers by acquiring domestic plants and animals, as well as knowledge, from neighbouring farmers. Here we use the dates of about 900 archaeological sites to compute a speed map of the spread of the Neolithic transition in Europe. We compare the speed map to the speed ranges predicted by purely demic, demic–cultural and purely cultural models. The comparison indicates that the transition was cultural in Northern Europe, the Alpine region and west of the Black Sea. But demic diffusion was at work in other regions such as the Balkans and Central Europe. Our models can be applied to many other cultural traits. We also propose that genetic data could be gathered and used to measure the demic kernels of Early Neolithic populations. This would lead to an enormous advance in Neolithic spread modelling. PMID:25977959

  13. Point Cloud and Digital Surface Model Generation from High Resolution Multiple View Stereo Satellite Imagery

    NASA Astrophysics Data System (ADS)

    Gong, K.; Fritsch, D.

    2018-05-01

    Nowadays, multiple-view stereo satellite imagery has become a valuable data source for digital surface model generation and 3D reconstruction. In 2016, a well-organized multiple view stereo publicly benchmark for commercial satellite imagery has been released by the John Hopkins University Applied Physics Laboratory, USA. This benchmark motivates us to explore the method that can generate accurate digital surface models from a large number of high resolution satellite images. In this paper, we propose a pipeline for processing the benchmark data to digital surface models. As a pre-procedure, we filter all the possible image pairs according to the incidence angle and capture date. With the selected image pairs, the relative bias-compensated model is applied for relative orientation. After the epipolar image pairs' generation, dense image matching and triangulation, the 3D point clouds and DSMs are acquired. The DSMs are aligned to a quasi-ground plane by the relative bias-compensated model. We apply the median filter to generate the fused point cloud and DSM. By comparing with the reference LiDAR DSM, the accuracy, the completeness and the robustness are evaluated. The results show, that the point cloud reconstructs the surface with small structures and the fused DSM generated by our pipeline is accurate and robust.

  14. Demic and cultural diffusion propagated the Neolithic transition across different regions of Europe.

    PubMed

    Fort, Joaquim

    2015-05-06

    The Neolithic transition is the shift from hunting–gathering into farming. About 9000 years ago, the Neolithic transition began to spread from the Near East into Europe, until it reached Northern Europe about 5500 years ago. There are two main models of this spread. The demic model assumes that it was mainly due to the reproduction and dispersal of farmers. The cultural model assumes that European hunter-gatherers become farmers by acquiring domestic plants and animals, as well as knowledge, from neighbouring farmers. Here we use the dates of about 900 archaeological sites to compute a speed map of the spread of the Neolithic transition in Europe. We compare the speed map to the speed ranges predicted by purely demic, demic-cultural and purely cultural models. The comparison indicates that the transition was cultural in Northern Europe, the Alpine region and west of the Black Sea. But demic diffusion was at work in other regions such as the Balkans and Central Europe. Our models can be applied to many other cultural traits. We also propose that genetic data could be gathered and used to measure the demic kernels of Early Neolithic populations. This would lead to an enormous advance in Neolithic spread modelling.

  15. MESSENGER Final Image

    NASA Image and Video Library

    2015-04-30

    Today, the MESSENGER spacecraft sent its final image. Originally planned to orbit Mercury for one year, the mission exceeded all expectations, lasting for over four years and acquiring extensive datasets with its seven scientific instruments and radio science investigation. This afternoon, the spacecraft succumbed to the pull of solar gravity and impacted Mercury's surface. The image shown here is the last one acquired and transmitted back to Earth by the mission. The image is located within the floor of the 93-kilometer-diameter crater Jokai. The spacecraft struck the planet just north of Shakespeare basin. Date acquired: April 30, 2015 Image Mission Elapsed Time (MET): 72716050 Image ID: 8422953 Instrument: Narrow Angle Camera (NAC) of the Mercury Dual Imaging System (MDIS) Center Latitude: 72.0° Center Longitude: 223.8° E Resolution: 2.1 meters/pixel Scale: This image is about 1 kilometers (0.6 miles) across Incidence Angle: 57.9° Emission Angle: 56.5° Phase Angle: 40.7° http://photojournal.jpl.nasa.gov/catalog/PIA19448

  16. Sunlit Terraces

    NASA Image and Video Library

    2015-02-09

    The exterior of this unnamed crater is in shadow, while the inner wall and terraces bask in the sunshine. Terraces form just after the crater has been excavated, when oversteepened slopes slump back down. This image was acquired as part of the MDIS low-altitude imaging campaign. During MESSENGER's second extended mission, the spacecraft makes a progressively closer approach to Mercury's surface than at any previous point in the mission, enabling the acquisition of high-spatial-resolution data. For spacecraft altitudes below 350 kilometers, NAC images are acquired with pixel scales ranging from 20 meters to as little as 2 meters. Date acquired: January 23, 2015 Image Mission Elapsed Time (MET): 64352478 Image ID: 7849599 Instrument: Narrow Angle Camera (NAC) of the Mercury Dual Imaging System (MDIS) Center Latitude: 31.48° Center Longitude: 81.89° E Resolution: 6 meters/pixel Scale: This scene is approximately 6.3 km (3.9 miles) from top to bottom Incidence Angle: 82.6° Emission Angle: 0.1° Phase Angle: 82.7° http://photojournal.jpl.nasa.gov/catalog/PIA19196

  17. Immediate-Early Gene Transcriptional Activation in Hippocampus Ca1 and Ca3 Does Not Accurately Reflect Rapid, Pattern Completion-Based Retrieval of Context Memory

    ERIC Educational Resources Information Center

    Pevzner, Aleksandr; Guzowski, John F.

    2015-01-01

    No studies to date have examined whether immediate-early gene (IEG) activation is driven by context memory recall. To address this question, we utilized the context preexposure facilitation effect (CPFE) paradigm. In CPFE, animals acquire contextual fear conditioning through hippocampus-dependent rapid retrieval of a previously formed contextual…

  18. The Meaningful Identity: A Longitudinal Look at the Interplay between Identity and Meaning in Life in Adolescence

    ERIC Educational Resources Information Center

    Negru-Subtirica, Oana; Pop, Eleonora Ioana; Luyckx, Koen; Dezutter, Jessie; Steger, Michael F.

    2016-01-01

    Identity formation in adolescence is closely linked to searching for and acquiring meaning in one's life. To date little is known about the manner in which these 2 constructs may be related in this developmental stage. In order to shed more light on their longitudinal links, we conducted a 3-wave longitudinal study, investigating how identity…

  19. 78 FR 32214 - Land Acquisitions: Appeals of Land Acquisition Decisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ...; 134D0102DR-DS5A300000-DR.5A311.IA000113; Docket ID: BIA-2013-0005] RIN 1076-AF15 Land Acquisitions: Appeals... trust under this part, including broadening notice of any right to file an administrative appeal. DATES... the United States acquired title. See, e.g., Neighbors for Rational Dev., Inc. v. Norton, 379 F.3d 956...

  20. The Accessibility of Learning Content for All Students, Including Students with Disabilities, Must Be Addressed in the Shift to Digital Instructional Materials. SETDA Policy Brief

    ERIC Educational Resources Information Center

    Fletcher, Geoff; Levin, Doug; Lipper, Katherine; Leichty, Reg

    2014-01-01

    This is a time of rapid technological advancement, with innovations in education holding great promise for improving teaching and learning, particularly for students with unique needs. High-quality digital educational materials, tools, and resources offer students relevant, up-to-date, and innovative ways to acquire knowledge and skills. Created…

  1. 76 FR 65510 - Notice of Proposals To Engage in or To Acquire Companies Engaged in Permissible Nonbanking...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ...' Loan Act (HOLA) (12 U.S.C. 1461 et seq.), and Regulation LL (12 CFR part 238) or Regulation MM (12 CFR....54) or 239.8 of Regulation MM (12 CFR 239.8). Unless otherwise noted, these activities will be... MM. Board of Governors of the Federal Reserve System. Dated: October 17, 2011. Robert deV. Frierson...

  2. New methods for the condition monitoring of level crossings

    NASA Astrophysics Data System (ADS)

    García Márquez, Fausto Pedro; Pedregal, Diego J.; Roberts, Clive

    2015-04-01

    Level crossings represent a high risk for railway systems. This paper demonstrates the potential to improve maintenance management through the use of intelligent condition monitoring coupled with reliability centred maintenance (RCM). RCM combines advanced electronics, control, computing and communication technologies to address the multiple objectives of cost effectiveness, improved quality, reliability and services. RCM collects digital and analogue signals utilising distributed transducers connected to either point-to-point or digital bus communication links. Assets in many industries use data logging capable of providing post-failure diagnostic support, but to date little use has been made of combined qualitative and quantitative fault detection techniques. The research takes the hydraulic railway level crossing barrier (LCB) system as a case study and develops a generic strategy for failure analysis, data acquisition and incipient fault detection. For each barrier the hydraulic characteristics, the motor's current and voltage, hydraulic pressure and the barrier's position are acquired. In order to acquire the data at a central point efficiently, without errors, a distributed single-cable Fieldbus is utilised. This allows the connection of all sensors through the project's proprietary communication nodes to a high-speed bus. The system developed in this paper for the condition monitoring described above detects faults by means of comparing what can be considered a 'normal' or 'expected' shape of a signal with respect to the actual shape observed as new data become available. ARIMA (autoregressive integrated moving average) models were employed for detecting faults. The statistical tests known as Jarque-Bera and Ljung-Box have been considered for testing the model.

  3. Community Coordinated Modeling Center: Addressing Needs of Operational Space Weather Forecasting

    NASA Technical Reports Server (NTRS)

    Kuznetsova, M.; Maddox, M.; Pulkkinen, A.; Hesse, M.; Rastaetter, L.; Macneice, P.; Taktakishvili, A.; Berrios, D.; Chulaki, A.; Zheng, Y.; hide

    2012-01-01

    Models are key elements of space weather forecasting. The Community Coordinated Modeling Center (CCMC, http://ccmc.gsfc.nasa.gov) hosts a broad range of state-of-the-art space weather models and enables access to complex models through an unmatched automated web-based runs-on-request system. Model output comparisons with observational data carried out by a large number of CCMC users open an unprecedented mechanism for extensive model testing and broad community feedback on model performance. The CCMC also evaluates model's prediction ability as an unbiased broker and supports operational model selections. The CCMC is organizing and leading a series of community-wide projects aiming to evaluate the current state of space weather modeling, to address challenges of model-data comparisons, and to define metrics for various user s needs and requirements. Many of CCMC models are continuously running in real-time. Over the years the CCMC acquired the unique experience in developing and maintaining real-time systems. CCMC staff expertise and trusted relations with model owners enable to keep up to date with rapid advances in model development. The information gleaned from the real-time calculations is tailored to specific mission needs. Model forecasts combined with data streams from NASA and other missions are integrated into an innovative configurable data analysis and dissemination system (http://iswa.gsfc.nasa.gov) that is accessible world-wide. The talk will review the latest progress and discuss opportunities for addressing operational space weather needs in innovative and collaborative ways.

  4. Competition for resources can explain patterns of social and individual learning in nature.

    PubMed

    Smolla, Marco; Gilman, R Tucker; Galla, Tobias; Shultz, Susanne

    2015-09-22

    In nature, animals often ignore socially available information despite the multiple theoretical benefits of social learning over individual trial-and-error learning. Using information filtered by others is quicker, more efficient and less risky than randomly sampling the environment. To explain the mix of social and individual learning used by animals in nature, most models penalize the quality of socially derived information as either out of date, of poor fidelity or costly to acquire. Competition for limited resources, a fundamental evolutionary force, provides a compelling, yet hitherto overlooked, explanation for the evolution of mixed-learning strategies. We present a novel model of social learning that incorporates competition and demonstrates that (i) social learning is favoured when competition is weak, but (ii) if competition is strong social learning is favoured only when resource quality is highly variable and there is low environmental turnover. The frequency of social learning in our model always evolves until it reduces the mean foraging success of the population. The results of our model are consistent with empirical studies showing that individuals rely less on social information where resources vary little in quality and where there is high within-patch competition. Our model provides a framework for understanding the evolution of social learning, a prerequisite for human cumulative culture. © 2015 The Author(s).

  5. Documentation and virtual reconstruction of historical objects in Peru damaged by an earthquake and climatic events

    NASA Astrophysics Data System (ADS)

    Hanzalová, K.; Pavelka, K.

    2013-07-01

    This paper deals with the possibilities of creating a 3-D model and a visualization technique for a presentation of historical buildings and sites in Peru. The project Nasca/CTU is documenting historical objects by using several techniques. This paper describes the documentation and the visualization of two historical churches (San Jose and San Xavier Churches) and the pre-Hispanic archaeological site La Ciudad Perdida de Huayuri (Abandoned town near Huayuri) in Nasca region by using photogrammetry and remote sensing. Both churches were damaged by an earthquake. We use different process for the documentation of these objects. Firstly, PhotoModeler software was used for the photogrammetric data processing of the acquired images. The subsequent making models of both churches were different too. Google SketchUp software was used for the San Jose Church and the 3-D model of San Xavier Church was created in MicroStation software. While in the modelling of the "Abandoned town" near Huayuri, which was destroyed by a climatic event (El Niño), the terrestrial photogrammetry, satellite data and GNSS measurement were applied. The general output of the project is a thematic map of this archaeological site; C14 method was used for dating.

  6. Competition for resources can explain patterns of social and individual learning in nature

    PubMed Central

    Smolla, Marco; Gilman, R. Tucker; Galla, Tobias; Shultz, Susanne

    2015-01-01

    In nature, animals often ignore socially available information despite the multiple theoretical benefits of social learning over individual trial-and-error learning. Using information filtered by others is quicker, more efficient and less risky than randomly sampling the environment. To explain the mix of social and individual learning used by animals in nature, most models penalize the quality of socially derived information as either out of date, of poor fidelity or costly to acquire. Competition for limited resources, a fundamental evolutionary force, provides a compelling, yet hitherto overlooked, explanation for the evolution of mixed-learning strategies. We present a novel model of social learning that incorporates competition and demonstrates that (i) social learning is favoured when competition is weak, but (ii) if competition is strong social learning is favoured only when resource quality is highly variable and there is low environmental turnover. The frequency of social learning in our model always evolves until it reduces the mean foraging success of the population. The results of our model are consistent with empirical studies showing that individuals rely less on social information where resources vary little in quality and where there is high within-patch competition. Our model provides a framework for understanding the evolution of social learning, a prerequisite for human cumulative culture. PMID:26354936

  7. The WEIZMASS spectral library for high-confidence metabolite identification

    NASA Astrophysics Data System (ADS)

    Shahaf, Nir; Rogachev, Ilana; Heinig, Uwe; Meir, Sagit; Malitsky, Sergey; Battat, Maor; Wyner, Hilary; Zheng, Shuning; Wehrens, Ron; Aharoni, Asaph

    2016-08-01

    Annotation of metabolites is an essential, yet problematic, aspect of mass spectrometry (MS)-based metabolomics assays. The current repertoire of definitive annotations of metabolite spectra in public MS databases is limited and suffers from lack of chemical and taxonomic diversity. Furthermore, the heterogeneity of the data prevents the development of universally applicable metabolite annotation tools. Here we present a combined experimental and computational platform to advance this key issue in metabolomics. WEIZMASS is a unique reference metabolite spectral library developed from high-resolution MS data acquired from a structurally diverse set of 3,540 plant metabolites. We also present MatchWeiz, a multi-module strategy using a probabilistic approach to match library and experimental data. This strategy allows efficient and high-confidence identification of dozens of metabolites in model and exotic plants, including metabolites not previously reported in plants or found in few plant species to date.

  8. High-resolution lidar topography of the Puget Lowland, Washington - A bonanza for earth science

    USGS Publications Warehouse

    Haugerud, R.A.; Harding, D.J.; Johnson, S.Y.; Harless, J.L.; Weaver, C.S.; Sherrod, B.L.

    2003-01-01

    More than 10,000 km2 of high-resolution, public-domain topography acquired by the Puget Sound Lidar Consortium is revolutionizing investigations of active faulting, continental glaciation, landslides, and surficial processes in the seismically active Puget Lowland. The Lowland-the population and economic center of the Pacific Northwest-presents special problems for hazards investigations, with its young glacial topography, dense forest cover, and urbanization. Lidar mapping during leaf-off conditions has led to a detailed digital model of the landscape beneath the forest canopy. The surface thus revealed contains a rich and diverse record of previously unknown surface-rupturing faults, deep-seated landslides, uplifted Holocene and Pleistocene beaches, and subglacial and periglacial features. More than half a dozen suspected postglacial fault scarps have been identified to date. Five scarps that have been trenched show evidence of large, Holocene, surface-rupturing earthquakes.

  9. Understanding mutagenesis through delineation of mutational signatures in human cancer

    DOE PAGES

    Petljak, Mia; Alexandrov, Ludmil B.

    2016-05-04

    Each individual cell within a human body acquires a certain number of somatic mutations during a course of its lifetime. These mutations originate from a wide spectra of both endogenous and exogenous mutational processes that leave distinct patterns of mutations, termed mutational signatures, embedded within the genomes of all cells. In recent years, the vast amount of data produced by sequencing of cancer genomes was coupled with novel mathematical models and computational tools to generate the first comprehensive map of mutational signatures in human cancer. Up to date, >30 distinct mutational signatures have been identified, and etiologies have been proposedmore » for many of them. This paper provides a brief historical background on examination of mutational patterns in human cancer, summarizes the knowledge accumulated since introducing the concept of mutational signatures and discusses their future potential applications and perspectives within the field.« less

  10. 3D printed simulation models based on real patient situations for hands-on practice.

    PubMed

    Kröger, E; Dekiff, M; Dirksen, D

    2017-11-01

    During the last few years, the curriculum of many dentistry schools in Germany has been reorganised. Two key aspects of the applied changes are the integration of up-to-date teaching methods and the promotion of interdisciplinarity. To support these efforts, an approach to fabricating individualised simulation models for hands-on courses employing 3D printing is presented. The models are based on real patients, thus providing students a more realistic preparation for real clinical situations. As a wide variety of dental procedures can be implemented, the simulation models can also contribute to a more interdisciplinary dental education. The data used for the construction of the models were acquired by 3D surface scanning. The data were further processed with 3D modelling software. Afterwards, the models were fabricated by 3D printing with the PolyJet technique. Three models serve as examples: a prosthodontic model for training veneer preparation, a conservative model for practicing dental bonding and an interdisciplinary model featuring carious teeth and an insufficient crown. The third model was evaluated in a hands-on course with 22 fourth-year dental students. The students answered a questionnaire and gave their personal opinion. Whilst the concept of the model received very positive feedback, some aspects of the implementation were criticised. We discuss these observations and suggest ways for further improvement. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. A new approach for dating Quaternary volcanism by TL: The example of the Eifel Volcanic Field, Germany

    NASA Astrophysics Data System (ADS)

    Zoeller, Ludwig; Richter, Daniel; Klinger, Philip; van den Bogaard, Paul

    2013-04-01

    Middle to Upper Pleistocene and Holocene volcanic eruptions are difficult to date by Ar/Ar techniques when K-rich minerals such as sanidines are not present, as is the case in mafic and some intermediate rocks. However, these may contain phlogopite crystals suitable for Ar/Ar dating. Direct luminescence dating of volcanic feldspar is hampered by a poorly understood phenomenon of long-term signal instability called "anomalous fading" which, however, is apparently not present in quartz. To circumvent the fading problem involved in luminescence dating of volcanic rocks lacking quartz we sampled quartz-bearing crustal xenoliths from the Quaternary West and the East Eifel Volcanic Fields. Sufficient heating for zeroing of the acquired geological TL during eruption is sometimes but not always visible in the field and among others depends on the size of the xenolith. Quartz grains were extracted from the xenoliths by crushing, density separation and etching in HF or H2SiF6. The orange-red TL emission from quartz is known to have a very high saturation dose and was therefore employed using a new "lexsyg" luminescence reader equipped with a special detection unit for measuring this orange-red TL emission. Additionally, the existing data base of Ar/Ar dating results is increased by a series of new laser ablation step heating Ar/Ar dating results from samples extracted from identical volcanic eruptions. These can serve as verification of the luminescence dating attempts. Some first preliminary TL dating results in the range up to ca. 500 ka will be presented and discussed. Apparently, some TL ages from quartz extracts underestimate the Ar/Ar ages significantly. Possible explanations of age underestimates will be presented for discussion.

  12. Normalizing Landsat and ASTER Data Using MODIS Data Products for Forest Change Detection

    NASA Technical Reports Server (NTRS)

    Gao, Feng; Masek, Jeffrey G.; Wolfe, Robert E.; Tan, Bin

    2010-01-01

    Monitoring forest cover and its changes are a major application for optical remote sensing. In this paper, we present an approach to integrate Landsat, ASTER and MODIS data for forest change detection. Moderate resolution (10-100m) images (e.g. Landsat and ASTER) acquired from different seasons and times are normalized to one "standard" date using MODIS data products as reference. The normalized data are then used to compute forest disturbance index for forest change detection. Comparing to the results from original data, forest disturbance index from the normalized images is more consistent spatially and temporally. This work demonstrates an effective approach for mapping forest change over a large area from multiple moderate resolution sensors on various acquisition dates.

  13. Experimental Evidence for the Los Alamos Proton Storage Ring Beam Instability

    NASA Astrophysics Data System (ADS)

    Plum, M.; Fitzgerald, D. H.; Macek, R.; Sander, O.; Thiessen, H. A.; Wang, T. S.; Wilkinson, C.

    1997-05-01

    Although the exact instability mechanism at the Proton Storage Ring (PSR) has not yet been conclusively identified, the evidence gathered to date is consistent with an e-p instability. We have recently acquired new data which shows that clearing electrodes significantly affect the instability threshold. A set of comprehensive measurements is also planned for the first months of 1997. In this paper we will present our latest data.

  14. LANDSAT: Non-US standard catalog 1-31 December 1976. [LANDSAT imagery for December 1976

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The Non-U.S. Standard Catalog lists Non-U.S. imagery acquired by LANDSAT 1 and LANDSAT 2 which has been processed and input to the data files during the referenced month. Data, such as date required, cloud cover and image quality are given for each scene. The microfilm roll and frame on which the scene may be found are also given.

  15. 26 CFR 1.1015-1 - Basis of property acquired by gift after December 31, 1920.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... sections 1016 and 1017) is greater than the fair market value of the property at the time of the gift. In such case, the basis for determining loss is the fair market value at the time of the gift. (2) The... fair market value of the property at the date of gift is $90,000. A later sells the property for $95...

  16. AirMSPI Level 1B2 V003 New and Reprocessed Data

    Atmospheric Science Data Center

    2013-12-10

    AirMSPI Level 1B2 V003 New and Reprocessed Data PODEX Thursday, December 12, ... The V001 & V002 data were reprocessed as V003, as well as new Pacific targets acquired on February 1, 2013. This release also includes both a terrain and an ellipsoid kml file per date/time/target. More details about the PODEX campaign and AirMSPI participation can be ...

  17. Robotics in near-earth space

    NASA Technical Reports Server (NTRS)

    Card, Michael E.

    1991-01-01

    The areas of space exploration in which robotic devices will play a part are identified, and progress to date in the space agency plans to acquire this capability is briefly reviewed. Roles and functions on orbit for robotic devices include well known activities, such as inspection and maintenance, assembly, docking, berthing, deployment, retrieval, materials handling, orbital replacement unit exchange, and repairs. Missions that could benefit from a robotic capability are discussed.

  18. High-quality observation of surface imperviousness for urban runoff modelling using UAV imagery

    NASA Astrophysics Data System (ADS)

    Tokarczyk, P.; Leitao, J. P.; Rieckermann, J.; Schindler, K.; Blumensaat, F.

    2015-10-01

    Modelling rainfall-runoff in urban areas is increasingly applied to support flood risk assessment, particularly against the background of a changing climate and an increasing urbanization. These models typically rely on high-quality data for rainfall and surface characteristics of the catchment area as model input. While recent research in urban drainage has been focusing on providing spatially detailed rainfall data, the technological advances in remote sensing that ease the acquisition of detailed land-use information are less prominently discussed within the community. The relevance of such methods increases as in many parts of the globe, accurate land-use information is generally lacking, because detailed image data are often unavailable. Modern unmanned aerial vehicles (UAVs) allow one to acquire high-resolution images on a local level at comparably lower cost, performing on-demand repetitive measurements and obtaining a degree of detail tailored for the purpose of the study. In this study, we investigate for the first time the possibility of deriving high-resolution imperviousness maps for urban areas from UAV imagery and of using this information as input for urban drainage models. To do so, an automatic processing pipeline with a modern classification method is proposed and evaluated in a state-of-the-art urban drainage modelling exercise. In a real-life case study (Lucerne, Switzerland), we compare imperviousness maps generated using a fixed-wing consumer micro-UAV and standard large-format aerial images acquired by the Swiss national mapping agency (swisstopo). After assessing their overall accuracy, we perform an end-to-end comparison, in which they are used as an input for an urban drainage model. Then, we evaluate the influence which different image data sources and their processing methods have on hydrological and hydraulic model performance. We analyse the surface runoff of the 307 individual subcatchments regarding relevant attributes, such as peak runoff and runoff volume. Finally, we evaluate the model's channel flow prediction performance through a cross-comparison with reference flow measured at the catchment outlet. We show that imperviousness maps generated from UAV images processed with modern classification methods achieve an accuracy comparable to standard, off-the-shelf aerial imagery. In the examined case study, we find that the different imperviousness maps only have a limited influence on predicted surface runoff and pipe flows, when traditional workflows are used. We expect that they will have a substantial influence when more detailed modelling approaches are employed to characterize land use and to predict surface runoff. We conclude that UAV imagery represents a valuable alternative data source for urban drainage model applications due to the possibility of flexibly acquiring up-to-date aerial images at a quality compared with off-the-shelf image products and a competitive price at the same time. We believe that in the future, urban drainage models representing a higher degree of spatial detail will fully benefit from the strengths of UAV imagery.

  19. Exploring the capacity of radar remote sensing to estimate wetland marshes water storage.

    PubMed

    Grings, F; Salvia, M; Karszenbaum, H; Ferrazzoli, P; Kandus, P; Perna, P

    2009-05-01

    This paper focuses on the use of radar remote sensing for water storage estimation in wetland marshes of the Paraná River Delta in Argentina. The approach followed is based on the analysis of a temporal set of ENVISAT ASAR data which includes images acquired under different polarizations and incidence angles as well as different environmental conditions (water level, precipitation, and vegetation condition). Two marsh species, named junco and cortadera, were monitored. This overall data set gave us the possibility of studying and understanding the basic interactions between the radar, the soil under different flood conditions, and the vegetation structure. The comprehension of the observed features was addressed through electromagnetic models developed for these ecosystems. The procedure used in this work to estimate water level within marshes combines a direct electromagnetic model, field work data specifically obtained to feed the model, the actual ASAR measurements and a well known retrieval scheme based on a cost function. Results are validated with water level evaluations at specific points. A map showing an estimation of the water storage capacity and its error in junco and cortadera areas for the date where the investigation was done is also presented.

  20. Acquired myospherulosis secondary to gluteal augmentation on fine needle aspiration cytology: A diagnostic challenge.

    PubMed

    Alperstein, Susan; Dilcher, Thomas; Viswanathan, Kartik; Rao, Rema A; Siddiqui, Momin T; Giorgadze, Tamara

    2018-05-01

    A 30-year-old female presented with a three-month history of a multilocular cystic lesion over the lumbosacral spine. Fine-needle aspiration biopsy (FNA) of the lesion was performed at an outside institution, and a cytologic diagnosis, suspicious for chordoma, was rendered. The patient presented for surgical consultation at our institution. Repeat FNA demonstrated an unusual fat-like material. Upon further inquiry, the patient provided a recent history of gluteal contour improvement with fibroadipose tissue implants. A diagnosis of myospherulosis was made with a concurrent surgical pathology correlation. No evidence of chordoma was identified. To date, this is the first reported case of acquired myospherulosis in the context of gluteal contour enhancement and represents an important diagnostic pitfall to consider on cytology preparations. © 2017 Wiley Periodicals, Inc.

  1. Ligand binding was acquired during evolution of nuclear receptors

    PubMed Central

    Escriva, Hector; Safi, Rachid; Hänni, Catherine; Langlois, Marie-Claire; Saumitou-Laprade, Pierre; Stehelin, Dominique; Capron, André; Pierce, Raymond; Laudet, Vincent

    1997-01-01

    The nuclear receptor (NR) superfamily comprises, in addition to ligand-activated transcription factors, members for which no ligand has been identified to date. We demonstrate that orphan receptors are randomly distributed in the evolutionary tree and that there is no relationship between the position of a given liganded receptor in the tree and the chemical nature of its ligand. NRs are specific to metazoans, as revealed by a screen of NR-related sequences in early- and non-metazoan organisms. The analysis of the NR gene duplication pattern during the evolution of metazoans shows that the present NR diversity arose from two waves of gene duplications. Strikingly, our results suggest that the ancestral NR was an orphan receptor that acquired ligand-binding ability during subsequent evolution. PMID:9192646

  2. Ovation Pharmaceuticals, Inc.

    PubMed

    Deutsch, Barry

    2002-11-01

    Ovation Pharmaceuticals, Inc. is a privately held specialty pharmaceutical company that focuses on products in central nervous system (CNS) disorders, oncology and other therapeutic areas where a small number of specialized physicians treat patients. Ovation serves unmet medical needs by acquiring underpromoted branded pharmaceutical products and promising late-stage development products no longer being actively promoted or developed by larger companies. Ovation supports acquired products through active sales and marketing activities and a clinical development program focused on new formulations, new indications and other product improvements. In April 2002, Ovation received a US$150 million commitment in private equity financing, believed to be the largest private equity investment received to date by an early-stage specialty pharmaceutical firm. Ovation used a portion of those funds to purchase its first two products from a major pharmaceutical company in August 2002.

  3. Systematic study of magnetar outbursts

    NASA Astrophysics Data System (ADS)

    Coti Zelati, Francesco; Rea, Nanda; Pons, José A.; Campana, Sergio; Esposito, Paolo

    2018-02-01

    We present the results of the systematic study of all magnetar outbursts observed to date, through a reanalysis of data acquired in about 1100 X-ray observations. We track the temporal evolution of the outbursts' soft X-ray spectral properties and the luminosities of the single spectral components as well as of the total emission. We model empirically all outburst light curves, and estimate the characteristic decay time-scales as well as the energetics involved. We investigate the link between different parameters (e.g. the luminosity at the peak of the outburst and in quiescence, the maximum luminosity increase, the decay time-scale and energy of the outburst, the neutron star surface dipolar magnetic field and characteristic age, etc.), and unveil several correlations among these quantities. We discuss our results in the context of the internal crustal heating and twisted bundle models for magnetar outbursts. This study is complemented by the Magnetar Outburst Online Catalogue (http://magnetars.ice.csic.es), an interactive data base where the user can plot any combination of the parameters derived in this work, and download all data.

  4. An Explanatory Model of Dating Violence Risk Factors in Spanish Adolescents.

    PubMed

    Aizpitarte, Alazne; Alonso-Arbiol, Itziar; Van de Vijver, Fons J R

    2017-12-01

    Dating violence is a serious public health issue that needs further understanding in terms of risk factors that may be involved in it. The main goal of this study was to test a mediational model of dating violence risk factors. The sample was composed of 477 secondary and college students from Spain (59% females). A dynamic developmental explanatory model considering aggressiveness, insecure attachment, interparental conflict, and peer dating violence was tested using a multigroup structural equation model. Aggressiveness partially mediated the relation between anxious attachment and dating violence and fully mediated the association between interparental conflict resolution and dating violence. Furthermore, perceived peer dating violence was a direct predictor of dating violence. Implications for prevention and intervention plans are discussed. © 2017 The Authors. Journal of Research on Adolescence © 2017 Society for Research on Adolescence.

  5. Importance of selecting archaeomagnetic data for geomagnetic modelling: example of the new Western Europe directional and intensity secular variation curves from 1500 BC to 200 AD

    NASA Astrophysics Data System (ADS)

    Herve, Gwenael; Chauvin, Annick; Lanos, Philippe

    2014-05-01

    At the regional scale, the dispersion between archaeomagnetic data and especially archaeointensities suggests that some of them may be biased. As a consequence, it appears necessary to perform a selection of available data before to compute mean regional secular variation curves or geomagnetic models. However the definition of suitable selection criteria is not obvious and we need to know how to manage "old" data acquired during the 60-70s. The Western Europe directional and intensity data set from 1500 BC to 200 AD allows to discuss these issues. It has recently been enhanced by 39 new archaeodirections and 23 new archaeointensities (Hervé et al., 2013a and 2013b data sets and 5 unpublished data). First, the whole Western Europe data set was selected but the strong dispersion restricted the accuracy and the reliability of the new Western Europe secular variation curves at Paris. The causes of the dispersion appear different between archaeodirections and archaeointensities. In the directional data set, the main problem comes from some age errors in the oldest published data. Since their publication their archaeological dating may have changed of 50 years or more. For intensity data that were acquired much more recently, the dispersion mainly results from the use of unreliable archaeointensity protocols. We propose a weighting approach based on the number of specimens and the use of pTRM-checks, anisotropy and cooling rate corrections. Only 63% of available archaeodirections and 32% of archaeointensities were used to build the new Western Europe secular variation curves from 1500 BC to 200 AD. These curves reveal that selecting the reference data avoids wrong estimations of the shape of the secular variation curves, the secular variation rate, the dating of archaeomagnetic jerks... Finally, it is worth pointing out that current geomagnetic global models take into account almost all the data that we decided to reject. It could partly explain why their predictions at Paris do not fit our local secular variation curves. Hervé, G., Chauvin, A. & Lanos, P., 2013a. Geomagnetic field variations in Western Europe from 1500BC to 200AD. Part I : Directional secular variation curve, Phys. Earth Planet. Inter., 218, 1-13. Hervé, G., Chauvin, A. & Lanos, P., 2013b. Geomagnetic field variations in Western Europe from 1500BC to 200AD. Part II : New intensity secular variation curve, Phys. Earth Planet. Inter., 218, 51-65.

  6. Comprehensive Care for Joint Replacement Model (CJR); Delay of Effective Date. Final rule; delay of effective date.

    PubMed

    2017-05-19

    This final rule finalizes May 20, 2017 as the effective date of the final rule titled "Advancing Care Coordination Through Episode Payment Models (EPMs); Cardiac Rehabilitation Incentive Payment Model; and Changes to the Comprehensive Care for Joint Replacement Model (CJR)" originally published in the January 3, 2017 Federal Register. This final rule also finalizes a delay of the applicability date of the regulations at 42 CFR part 512 from July 1, 2017 to January 1, 2018 and delays the effective date of the specific CJR regulations listed in the DATES section from July 1, 2017 to January 1, 2018.

  7. Characterizing GEO Titan Transtage Fragmentations using Ground-based Measurements

    NASA Technical Reports Server (NTRS)

    Cowardin, H.; Anz-Meador, P.

    2016-01-01

    In a continued effort to better characterize the Geosynchronous Orbit (GEO) environment, NASA's Orbital Debris Program Office (ODPO) utilizes various ground-based optical assets to acquire photometric and spectral data of known debris associated with fragmentations in or near GEO. The Titan IIIC Transtage upper stage is known to have fragmented four times. Two of the four fragmentations were in GEO while a third Transtage fragmented in GEO transfer orbit. The forth fragmentation occurred in Low Earth Orbit. In order to better assess what may be causing these fragmentations, the NASA ODPO recently acquired a Titan Transtage test and display article that was previously in the custody of the 309th Aerospace Maintenance and Regeneration Group (AMARG) in Tucson, Arizona. After initial inspections at AMARG demonstrated that the test article was of sufficient fidelity to be of interest, the test article was brought to JSC to continue material analysis and historical documentation of the Titan Transtage. The Transtage will be a subject of forensic analysis using spectral measurements to compare with telescopic data; as well, a scale model will be created to use in the Optical Measurement Center for photometric analysis of an intact Transtage, including a BRDF. The following presentation will provide a review of the Titan Transtage, the current analysis that has been done to date, and the future work to be completed in support of characterizing the GEO and near GEO orbital debris environment.

  8. Climate driven crop planting date in the ACME Land Model (ALM): Impacts on productivity and yield

    NASA Astrophysics Data System (ADS)

    Drewniak, B.

    2017-12-01

    Climate is one of the key drivers of crop suitability and productivity in a region. The influence of climate and weather on the growing season determine the amount of time crops spend in each growth phase, which in turn impacts productivity and, more importantly, yields. Planting date can have a strong influence on yields with earlier planting generally resulting in higher yields, a sensitivity that is also present in some crop models. Furthermore, planting date is already changing and may continue, especially if longer growing seasons caused by future climate change drive early (or late) planting decisions. Crop models need an accurate method to predict plant date to allow these models to: 1) capture changes in crop management to adapt to climate change, 2) accurately model the timing of crop phenology, and 3) improve crop simulated influences on carbon, nutrient, energy, and water cycles. Previous studies have used climate as a predictor for planting date. Climate as a plant date predictor has more advantages than fixed plant dates. For example, crop expansion and other changes in land use (e.g., due to changing temperature conditions), can be accommodated without additional model inputs. As such, a new methodology to implement a predictive planting date based on climate inputs is added to the Accelerated Climate Model for Energy (ACME) Land Model (ALM). The model considers two main sources of climate data important for planting: precipitation and temperature. This method expands the current temperature threshold planting trigger and improves the estimated plant date in ALM. Furthermore, the precipitation metric for planting, which synchronizes the crop growing season with the wettest months, allows tropical crops to be introduced to the model. This presentation will demonstrate how the improved model enhances the ability of ALM to capture planting date compared with observations. More importantly, the impact of changing the planting date and introducing tropical crops will be explored. Those impacts include discussions on productivity, yield, and influences on carbon and energy fluxes.

  9. Long-term cognitive and neurological outcome of preterm infants with postnatally acquired CMV infection through breast milk.

    PubMed

    Goelz, Rangmar; Meisner, Christoph; Bevot, Andrea; Hamprecht, Klaus; Kraegeloh-Mann, Ingeborg; Poets, Christian F

    2013-09-01

    Long-term follow-up data on preterm infants with breast milk-acquired postnatal cytomegalovirus (CMV) infection are sparse. To systematically evaluate the long-term cognitive outcome and prevalence of cerebral palsy (CP) in patients after postnatal CMV infection. All surviving infants <1500 g born in our centre between 1 June 1995 and 1 June 2000, and with postnatal CMV infection acquired at up to 3 months of corrected age, were eligible for our study; this included neurological and neurocognitive assessment, using the Kaufman Assessment Battery for Children (K-ABC) at the age of >4 years. A blinded and controlled matched-pairs design was used with gestational age, gender and date of birth as matching criteria. Of 50 eligible children, 42 (84%) could be tested. There was no difference in the prevalence of cerebral palsy. Following CMV infection during their hospital stay, infants had significantly lower results in the simultaneous processing scale of the K-ABC (p=0.029) after correction for additional risk factors like socioeconomic status (SES). Results for the sequential and achievement scales were only slightly reduced (p>0.05). It seems possible that breast milk-acquired CMV infection has a detrimental influence on cognitive development of preterm infants.

  10. Validation of Land Cover Maps Utilizing Astronaut Acquired Imagery

    NASA Technical Reports Server (NTRS)

    Estes, John E.; Gebelein, Jennifer

    1999-01-01

    This report is produced in accordance with the requirements outlined in the NASA Research Grant NAG9-1032 titled "Validation of Land Cover Maps Utilizing Astronaut Acquired Imagery". This grant funds the Remote Sensing Research Unit of the University of California, Santa Barbara. This document summarizes the research progress and accomplishments to date and describes current on-going research activities. Even though this grant has technically expired, in a contractual sense, work continues on this project. Therefore, this summary will include all work done through and 5 May 1999. The principal goal of this effort is to test the accuracy of a sub-regional portion of an AVHRR-based land cover product. Land cover mapped to three different classification systems, in the southwestern United States, have been subjected to two specific accuracy assessments. One assessment utilizing astronaut acquired photography, and a second assessment employing Landsat Thematic Mapper imagery, augmented in some cases, high aerial photography. Validation of these three land cover products has proceeded using a stratified sampling methodology. We believe this research will provide an important initial test of the potential use of imagery acquired from Shuttle and ultimately the International Space Station (ISS) for the operational validation of the Moderate Resolution Imaging Spectrometer (MODIS) land cover products.

  11. Validation of the new trapped environment AE9/AP9/SPM at low Earth orbit

    NASA Astrophysics Data System (ADS)

    Badavi, Francis F.

    2014-09-01

    The completion of the international space station (ISS) in 2011 has provided the space research community an ideal proving ground for future long duration human activities in space. Ionizing radiation measurements in ISS form the ideal tool for the validation of radiation environmental models, nuclear transport codes and nuclear reaction cross sections. Indeed, prior measurements on the space transportation system (STS; shuttle) provided vital information impacting both the environmental models and the nuclear transport code developments by indicating the need for an improved dynamic model of the low Earth orbit (LEO) trapped environment. Additional studies using thermo-luminescent detector (TLD), tissue equivalent proportional counter (TEPC) area monitors, and computer aided design (CAD) model of earlier ISS configurations, confirmed STS observations that, as input, computational dosimetry requires an environmental model with dynamic and directional (anisotropic) behavior, as well as an accurate six degree of freedom (DOF) definition of the vehicle attitude and orientation along the orbit of ISS. At LEO, a vehicle encounters exposure from trapped particles and attenuated galactic cosmic rays (GCR). Within the trapped field, a challenge arises from properly estimating the amount of exposure acquired. There exist a number of models to define the intensities of the trapped particles during the solar quiet and active times. At active times, solar energetic particles (SEP) generated by solar flare or coronal mass ejection (CME) also contribute to the exposure at high northern and southern latitudes. Among the more established trapped models are the historic and popular AE8/AP8, dating back to the 1980s, the historic and less popular CRRES electron/proton, dating back to 1990s and the recently released AE9/AP9/SPM. The AE9/AP9/SPM model is a major improvement over the older AE8/AP8 and CRRES models. This model is derived from numerous measurements acquired over four solar cycles dating back to the 1970s, roughly representing 40 years of data collection. In contrast, the older AE8/AP8 and CRRES models were limited to only a few months of measurements taken during the prior solar minima and maxima. The dual goal of this paper is to first validate the AE8/AP8 and AE9/AP9/SPM trapped models against ISS dosemetric measurements for a silicon based detector, to assess the improvements in the AE9/AP9/SPM model as compared to AE8/AP8 model. The validation is done at selected target points within ISS-6A configuration during its passage through the south Atlantic anomaly (SAA). For such validation, only the isotropic spectrum of either model is needed. As a second goal, the isotropic spectra of both trapped models are re-casted into anisotropic spectra by modulating them with a measurement derived angular formalism which is applicable to trapped protons. Since at LEO electrons have minimal exposure contribution, the paper ignores the AE8 and AE9 component of the models and presents the angular validation of AP8 and AP9 against measurements from the compact environment anomaly sensor (CEASE) science instrument package, flown onboard the tri-service experiment-5 (TSX-5) satellite during the period of June 2000-July 2006. The spin stabilized satellite was flown in a 410 × 1710 km, 69° inclination orbit, allowing it to be exposed to a broad range of LEO regime. Particular emphasize is put on the validation of proton flux profiles at differential 40 MeV and integral >40 MeV, in the vicinity of SAA where protons exhibit east-west (EW) anisotropy and have a relatively narrow pitch angle distribution. Within SAA, the EW anisotropy results in different level of exposure to each side of CEASE instrument package, allowing the extraction of anisotropic proton spectra from the measurements. While the magnitude of the EW effect at LEO depends on a multitude of factors such as trapped proton energy, orientation of the spacecraft along the velocity vector and altitude of the spacecraft, for this part, the paper draws quantitative conclusions on the combined effect of proton pitch angle and EW anomaly.

  12. Gulf Coast Subsidence: Integration of Geodesy, Geophysical Modeling, and Interferometric Synthetic Aperture Radar Observations

    NASA Astrophysics Data System (ADS)

    Blom, R. G.; Chapman, B. D.; Deese, R.; Dokka, R. K.; Fielding, E. J.; Hawkins, B.; Hensley, S.; Ivins, E. R.; Jones, C. E.; Kent, J. D.; Liu, Z.; Lohman, R.; Zheng, Y.

    2012-12-01

    The vulnerability of the US Gulf Coast has received increased attention in the years since hurricanes Katrina and Rita. Agencies responsible for the long-term protection of lives and infrastructure require precise estimates of future subsidence and sea level rise. A quantitative, geophysically based methodology can provide such estimates by incorporating geological data, geodetic measurements, geophysical models of non-elastic mechanical behavior at depth, and geographically comprehensive deformation monitoring made possible with measurements from Interferometric Synthetic Aperture Radar (InSAR). To be effective, results must be available to user agencies in a format suitable for integration within existing decision-support processes. Work to date has included analysis of historical and continuing ground-based geodetic measurements. These reveal a surprising degree of complexity, including regions that are subsiding at rates faster than those considered for hurricane protection planning of New Orleans and other coastal communities (http://www.mvn.usace.army.mil/pdf/hps_verticalsettlement.pdf) as well as Louisiana's coastal restoration strategies (http://www.coast2050.gov/2050reports.htm) (Dokka, 2011, J. Geophys. Res., 116, B06403, doi:10.1029/2010JB008008). Traditional geodetic measurements provide precise information at single points, while InSAR observations provide geographically comprehensive measurements of surface deformation at lower vertical precision. Available InSAR data sources include X-, C- and L-band satellite, and NASA/JPL airborne UAVSAR L-band data. The Gulf Coast environment is very challenging for InSAR techniques, especially with systems not designed for interferometry. For example, the shorter wavelength C-band data decorrelates over short time periods requiring more elaborate time-series analysis techniques, with which we've had some success. Meanwhile, preliminary analysis of limited L-Band ALOS/PALSAR satellite data show promise; unfortunately this Japanese satellite system failed in April 2011. We now have multiple airborne UAVSAR repeat pass interferometry data sets under analysis (http://uavsar.jpl.nasa.gov/) . UAVSAR interferogram processing has proven problematic in this environment, and new acquisitions are planned at shorter temporal intervals to yield improved results. Combining the geodetic and InSAR data can constrain geophysical models of crustal behavior, leading to quantitative predictions of future subsidence. Model results to date show good agreement between geodetic measurements and geophysically reasonable parameters including sediment load and ~130 m post-glacial sea level rise. We review work to date and present newly acquired UAVSAR data.

  13. Simulation of earthquake caused building damages for the development of fast reconnaissance techniques

    NASA Astrophysics Data System (ADS)

    Schweier, C.; Markus, M.; Steinle, E.

    2004-04-01

    Catastrophic events like strong earthquakes can cause big losses in life and economic values. An increase in the efficiency of reconnaissance techniques could help to reduce the losses in life as many victims die after and not during the event. A basic prerequisite to improve the rescue teams' work is an improved planning of the measures. This can only be done on the basis of reliable and detailed information about the actual situation in the affected regions. Therefore, a bundle of projects at Karlsruhe university aim at the development of a tool for fast information retrieval after strong earthquakes. The focus is on urban areas as the most losses occur there. In this paper the approach for a damage analysis of buildings will be presented. It consists of an automatic methodology to model buildings in three dimensions, a comparison of pre- and post-event models to detect changes and a subsequent classification of the changes into damage types. The process is based on information extraction from airborne laserscanning data, i.e. digital surface models (DSM) acquired through scanning of an area with pulsed laser light. To date, there are no laserscanning derived DSMs available to the authors that were taken of areas that suffered damages from earthquakes. Therefore, it was necessary to simulate such data for the development of the damage detection methodology. In this paper two different methodologies used for simulating the data will be presented. The first method is to create CAD models of undamaged buildings based on their construction plans and alter them artificially in such a way as if they had suffered serious damage. Then, a laserscanning data set is simulated based on these models which can be compared with real laserscanning data acquired of the buildings (in intact state). The other approach is to use measurements of actual damaged buildings and simulate their intact state. It is possible to model the geometrical structure of these damaged buildings based on digital photography taken after the event by evaluating the images with photogrammetrical methods. The intact state of the buildings is simulated based on on-site investigations, and finally laserscanning data are simulated for both states.

  14. Connectionist neuropsychology: uncovering ultimate causes of acquired dyslexia.

    PubMed

    Woollams, Anna M

    2014-01-01

    Acquired dyslexia offers a unique window on to the nature of the cognitive and neural architecture supporting skilled reading. This paper provides an integrative overview of recent empirical and computational work on acquired dyslexia within the context of the primary systems framework as implemented in connectionist neuropsychological models. This view proposes that damage to general visual, phonological or semantic processing abilities are the root causes of different forms of acquired dyslexia. Recent case-series behavioural evidence concerning pure alexia, phonological dyslexia and surface dyslexia that supports this perspective is presented. Lesion simulations of these findings within connectionist models of reading demonstrate the viability of this approach. The commitment of such models to learnt representations allows them to capture key aspects of performance in each type of acquired dyslexia, particularly the associated non-reading deficits, the role of relearning and the influence of individual differences in the premorbid state of the reading system. Identification of these factors not only advances our understanding of acquired dyslexia and the mechanisms of normal reading but they are also relevant to the complex interactions underpinning developmental reading disorders.

  15. Connectionist neuropsychology: uncovering ultimate causes of acquired dyslexia

    PubMed Central

    Woollams, Anna M.

    2014-01-01

    Acquired dyslexia offers a unique window on to the nature of the cognitive and neural architecture supporting skilled reading. This paper provides an integrative overview of recent empirical and computational work on acquired dyslexia within the context of the primary systems framework as implemented in connectionist neuropsychological models. This view proposes that damage to general visual, phonological or semantic processing abilities are the root causes of different forms of acquired dyslexia. Recent case-series behavioural evidence concerning pure alexia, phonological dyslexia and surface dyslexia that supports this perspective is presented. Lesion simulations of these findings within connectionist models of reading demonstrate the viability of this approach. The commitment of such models to learnt representations allows them to capture key aspects of performance in each type of acquired dyslexia, particularly the associated non-reading deficits, the role of relearning and the influence of individual differences in the premorbid state of the reading system. Identification of these factors not only advances our understanding of acquired dyslexia and the mechanisms of normal reading but they are also relevant to the complex interactions underpinning developmental reading disorders. PMID:24324241

  16. Acquired appetitive responding to intravenous nicotine reflects a Pavlovian conditioned association

    PubMed Central

    Murray, Jennifer E.; Bevins, Rick A.

    2008-01-01

    Recent research examining Pavlovian appetitive conditioning has extended the associative properties of nicotine from the unconditioned stimulus or reward to include the role of a conditional stimulus (CS), capable of acquiring the ability to evoke a conditioned response. To date, published research has used pre-session extravascular injections to examine nicotine as a contextual CS in that appetitive Pavlovian drug discrimination task. Two studies in the current research examined whether a nicotine CS can function discretely, multiple times within a session using passive intravenous infusions. In Experiment 1, rats readily acquired a discrimination in conditioned responding between nicotine and saline infusions when nicotine was selectively paired with sucrose presentations. In Experiment 2, rats were either trained with nicotine paired with sucrose or explicitly unpaired with sucrose. The results showed that rats trained with explicitly unpaired nicotine and sucrose did not increase dipper entries after the infusions. Nicotine was required to be reliably paired with sucrose for control of conditioned responding to develop. Implications of these findings are discussed in relation to tobacco addiction, learning theory, and pharmacology. PMID:19170434

  17. The VALiDATe29 MRI Based Multi-Channel Atlas of the Squirrel Monkey Brain.

    PubMed

    Schilling, Kurt G; Gao, Yurui; Stepniewska, Iwona; Wu, Tung-Lin; Wang, Feng; Landman, Bennett A; Gore, John C; Chen, Li Min; Anderson, Adam W

    2017-10-01

    We describe the development of the first digital atlas of the normal squirrel monkey brain and present the resulting product, VALiDATe29. The VALiDATe29 atlas is based on multiple types of magnetic resonance imaging (MRI) contrast acquired on 29 squirrel monkeys, and is created using unbiased, nonlinear registration techniques, resulting in a population-averaged stereotaxic coordinate system. The atlas consists of multiple anatomical templates (proton density, T1, and T2* weighted), diffusion MRI templates (fractional anisotropy and mean diffusivity), and ex vivo templates (fractional anisotropy and a structural MRI). In addition, the templates are combined with histologically defined cortical labels, and diffusion tractography defined white matter labels. The combination of intensity templates and image segmentations make this atlas suitable for the fundamental atlas applications of spatial normalization and label propagation. Together, this atlas facilitates 3D anatomical localization and region of interest delineation, and enables comparisons of experimental data across different subjects or across different experimental conditions. This article describes the atlas creation and its contents, and demonstrates the use of the VALiDATe29 atlas in typical applications. The atlas is freely available to the scientific community.

  18. Origins and consequences of technology acquirement by independent-living seniors: towards an integrative model.

    PubMed

    Peek, S T M; Luijkx, K G; Vrijhoef, H J M; Nieboer, M E; Aarts, S; van der Voort, C S; Rijnaard, M D; Wouters, E J M

    2017-08-22

    Living independently can be challenging for seniors. Technologies are expected to help older adults age in place, yet little empirical research is available on how seniors develop a need for technologies, how they acquire these technologies, and how these subsequently affect their lives. Aging is complex, dynamic and personal. But how does this translate to seniors' adoption and acceptance of technology? To better understand origins and consequences of technology acquirement by independent-living seniors, an explorative longitudinal qualitative field study was set up. Home visits were made to 33 community-dwelling seniors living in the Netherlands, on three occasions (2012-2014). Semi-structured interviews were conducted on the timeline of acquirements, and people and factors involved in acquirements. Additionally, participants were interviewed on experiences in using technologies since acquirement. Thematic analysis was employed to analyze interview transcripts, using a realist approach to better understand the contexts, mechanisms and outcomes of technology acquirements. Findings were accumulated in a new conceptual model: The Cycle of Technology Acquirement by Independent-Living Seniors (C-TAILS), which provides an integrative perspective on why and how technologies are acquired, and why these may or may not prove to be appropriate and effective, considering an independent-living senior's needs and circumstances at a given point in time. We found that externally driven and purely desire-driven acquirements led to a higher risk of suboptimal use and low levels of need satisfaction. Technology acquirement by independent-living seniors may be best characterized as a heterogeneous process with many different origins, pathways and consequences. Furthermore, technologies that are acquired in ways that are not congruent with seniors' personal needs and circumstances run a higher risk of proving to be ineffective or inappropriate. Yet, these needs and circumstances are subject to change, and the C-TAILS model can be employed to better understand contexts and mechanisms that come into play.

  19. Can phenological models predict tree phenology accurately in the future? The unrevealed hurdle of endodormancy break.

    PubMed

    Chuine, Isabelle; Bonhomme, Marc; Legave, Jean-Michel; García de Cortázar-Atauri, Iñaki; Charrier, Guillaume; Lacointe, André; Améglio, Thierry

    2016-10-01

    The onset of the growing season of trees has been earlier by 2.3 days per decade during the last 40 years in temperate Europe because of global warming. The effect of temperature on plant phenology is, however, not linear because temperature has a dual effect on bud development. On one hand, low temperatures are necessary to break bud endodormancy, and, on the other hand, higher temperatures are necessary to promote bud cell growth afterward. Different process-based models have been developed in the last decades to predict the date of budbreak of woody species. They predict that global warming should delay or compromise endodormancy break at the species equatorward range limits leading to a delay or even impossibility to flower or set new leaves. These models are classically parameterized with flowering or budbreak dates only, with no information on the endodormancy break date because this information is very scarce. Here, we evaluated the efficiency of a set of phenological models to accurately predict the endodormancy break dates of three fruit trees. Our results show that models calibrated solely with budbreak dates usually do not accurately predict the endodormancy break date. Providing endodormancy break date for the model parameterization results in much more accurate prediction of this latter, with, however, a higher error than that on budbreak dates. Most importantly, we show that models not calibrated with endodormancy break dates can generate large discrepancies in forecasted budbreak dates when using climate scenarios as compared to models calibrated with endodormancy break dates. This discrepancy increases with mean annual temperature and is therefore the strongest after 2050 in the southernmost regions. Our results claim for the urgent need of massive measurements of endodormancy break dates in forest and fruit trees to yield more robust projections of phenological changes in a near future. © 2016 John Wiley & Sons Ltd.

  20. Single or Dual Representations for Reading and Spelling?

    ERIC Educational Resources Information Center

    Holmes, Virginia M.; Babauta, Mariko L.

    2005-01-01

    Neuropsychological models postulate that the memory representation acquired for use in reading words is separate from the one acquired for use in spelling, while developmental models assume that the same representation is developed for access in both reading and spelling. The dual-representation model contends that there is often more precise…

  1. The use of a logistic regression model to develop a risk assessment of intraoperatively acquired pressure ulcer.

    PubMed

    Gao, Ling; Yang, Lina; Li, Xiaoqin; Chen, Jin; Du, Juan; Bai, Xiaoxia; Yang, Xianjun

    2018-04-20

    To screen the factors of intraoperatively acquired pressure ulcer and establish a new risk assessment model of intraoperatively acquired pressure ulcer. This is a prospective study. A total of 1,963 patients who received neurosurgery, orthopaedics, paediatric surgery and cardiac surgery therapy in Sichuan Academy of Medical Science and Provincial People's Hospital in China from October 2015-October 2016 were enrolled in the study, and their clinical parameters were collected. Multivariable logistic regression analysis and decision tree analysis were used to analyse and screen the factors of intraoperatively acquired pressure ulcer and establish the risk assessment model of intraoperatively acquired pressure ulcer. The risk factors for intraoperatively acquired pressure ulcer included the application of external force during operation (β = 1.10, OR = 3.20), lean body mass (β = 1.08, OR = 2.95), time of operation ≥6 hr (β = 2.66, OR = 14.30), prone position operation (β = 1.13, OR = 3.10), cardiopulmonary bypass during operation (β = 1.72, OR = 5.59) and intraoperative blood loss (β = 0.67, OR = 1.95). The new risk assessment model showed that the AUC of ROC curve was 0.897 (p < .001). According to the maximum principle of Youden's index, the sensitivity, specificity and Youden's index J of the model were 0.81, 0.88 and 0.69, respectively, when the cut-off point was set at π = 0.025. A new and relatively reliable assessment model for intraoperatively acquired pressure ulcer is established. Pressure ulcers remain a challenge in clinical nursing. A new risk assessment model of pressure ulcers that is applicable to surgical patients is highly recommended. © 2018 John Wiley & Sons Ltd.

  2. A Neural Network Model to Learn Multiple Tasks under Dynamic Environments

    NASA Astrophysics Data System (ADS)

    Tsumori, Kenji; Ozawa, Seiichi

    When environments are dynamically changed for agents, the knowledge acquired in an environment might be useless in future. In such dynamic environments, agents should be able to not only acquire new knowledge but also modify old knowledge in learning. However, modifying all knowledge acquired before is not efficient because the knowledge once acquired may be useful again when similar environment reappears and some knowledge can be shared among different environments. To learn efficiently in such environments, we propose a neural network model that consists of the following modules: resource allocating network, long-term & short-term memory, and environment change detector. We evaluate the model under a class of dynamic environments where multiple function approximation tasks are sequentially given. The experimental results demonstrate that the proposed model possesses stable incremental learning, accurate environmental change detection, proper association and recall of old knowledge, and efficient knowledge transfer.

  3. Bowhead whale behavior in relation to seismic exploration, Alaskan Beaufort Sea, Autumn 1981. Study report (Final)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fraker, M.A.; Ljungblad, D.K.; Richardson, W.J.

    1985-10-01

    Behavior of bowhead whales (Balsena mysticetus) in the eastern part of the Alaskan Beaufort Sea or near the Alaska/Yukon border was observed from a circling turbine-powered Goose aircraft on 10 dates from 12 September to 5 October 1981. On three of these dates, the whales were exposed t, noise impulses from seismic vessels 13 km or more away. Some behavioral data were acquired. In both the presence and the absence of seismic impulses, most bowheads appeared to be feeding in the water column, although slow travel and active socializing were sometimes detected. Sonobuoys detected bowhead calls both in the presencemore » and the absence of seismic impulses. There was no clear evidence of unusual behavior in the presence of seismic impulses.« less

  4. A greenhouse experiment for the identification of spectral indices for crop water and nitrogen status assessment

    NASA Astrophysics Data System (ADS)

    Marino Gallina, Pietro; Bechini, Luca; Cabassi, Giovanni; Cavalli, Daniele; Chiaradia, Enrico Antonio; Corti, Martina; Ferrante, Antonio; Martinetti, Livia; Masseroni, Daniele; Morgutti, Silvia; Nocito, Fabio Francesco; Facchi, Arianna

    2015-04-01

    Improvements in crop production depend on the correct adoption of agronomic and irrigation management strategies. The use of high spatial and temporal resolution monitoring methods may be used in precision agriculture to improve the efficiency in water and nutrient input management, guaranteeing the environmental sustainability of agricultural productions. In the last decades, many indices for the monitoring of water or nitrogen status of crops were developed by using multispectral images and, more recently, hyperspectral and thermal images acquired by satellite of airborne platforms. To date, however, comprehensive studies aimed at identifying indices as independent as possible for the management of the two types of stress are still scarce in the literature. Moreover, the chemometric approach for the statistical analysis of the acquired images is not yet widely experienced in this research area. In this context, this work presents the set-up of a greenhouse experiment that will start in February 2015 in Milan (Northern Italy), which aims to the objectives described above. The experiment will be carried out on two crops with a different canopy geometry (rice and spinach) subjected to four nitrogen treatments, for a total of 96 pots. Hyperspectral scanner and thermal images will be acquired at four phenological stages. At each phenological phase, acquisitions will be conducted on one-fourth of the pots, in the first instance in good water conditions and, subsequently, at different time steps after the cessation of irrigation. During the acquisitions, measurements of leaf area index and biomass, chlorophyll and nitrogen content in the plants, soil water content, stomatal conductance and leaf water potential will be performed. Moreover, on leaf samples, destructive biochemical analysis will be conducted to evaluate the physiological stress status of crops in the light of different irrigation and nutrient levels. Multivariate regression analysis between the acquired spectra and the chemical-physical properties of the crop determined with standard methods will be used to identify suitable models for the estimation of crop water and nitrogen status. The most significant wavelengths for the detection of water and nitrogen stress could be the subject of a future experimentation in open field conditions using multispectral systems.

  5. Age of Palos Verdes submarine debris avalanche, southern California

    USGS Publications Warehouse

    Normark, W.R.; McGann, M.; Sliter, R.

    2004-01-01

    The Palos Verdes debris avalanche is the largest, by volume, late Quaternary mass-wasted deposit recognized from the inner California Borderland basins. Early workers speculated that the sediment failure giving rise to the deposit is young, taking place well after sea level reached its present position. A newly acquired, closely-spaced grid of high-resolution, deep-tow boomer profiles of the debris avalanche shows that the Palos Verdes debris avalanche fills a turbidite leveed channel that extends seaward from San Pedro Sea Valley, with the bulk of the avalanche deposit appearing to result from a single failure on the adjacent slope. Radiocarbon dates from piston-cored sediment samples acquired near the distal edge of the avalanche deposit indicate that the main failure took place about 7500 yr BP. ?? 2003 Elsevier B.V. All rights reserved.

  6. Dopamine-System Genes and Cultural Acquisition: The Norm Sensitivity Hypothesis

    PubMed Central

    Kitayama, Shinobu; King, Anthony; Hsu, Ming; Liberzon, Israel; Yoon, Carolyn

    2016-01-01

    Previous research in cultural psychology shows that cultures vary in the social orientation of independence and interdependence. To date, however, little is known about how people may acquire such global patterns of cultural behavior or cultural norms. Nor is it clear what genetic mechanisms may underlie the acquisition of cultural norms. Here, we draw on recent evidence for certain genetic variability in the susceptibility to environmental influences and propose a norm sensitivity hypothesis, which holds that people acquire culture, and rules of cultural behaviors, through reinforcement-mediated social learning processes. One corollary of the hypothesis is that the degree of cultural acquisition should be influenced by polymorphic variants of genes involved in dopaminergic neural pathways, which have been widely implicated in reinforcement learning. We reviewed initial evidence for this prediction and discussed challenges and directions for future research. PMID:28491931

  7. Lessons from the history of the human immunodeficiency virus/acquired immunodeficiency syndrome epidemic among Spanish drug injectors.

    PubMed

    De La Fuente, L; Bravo, M J; Barrio, G; Parras, F; Suárez, M; Rodés, A; Noguer, I

    2003-12-15

    In Spain, approximately 10 years passed between the time when human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) harm-reduction programs should have been developed with sufficient coverage to have an optimum impact on public health (before the HIV/AIDS epidemic's explosion in 1984) and the date of their actual implementation. This delay yielded an enormous cost for the country. The introduction of the virus in drug injector networks during a period of widespread diffusion of heroin injection and the lack of political awareness of the growing problem were 2 important factors that contributed to the important diffusion of the HIV infection among Spanish injection drug users. Lessons can be learned that may be of great interest in countries or territories facing similar challenges now and in the future.

  8. Aspen Fire, Arizona

    NASA Image and Video Library

    2003-07-01

    On June 26, NASA's Terra satellite acquired this image of the Aspen fire burning out of control north of Tucson, AZ. As of that date, the fire had consumed more than 27,000 acres and destroyed more than 300 homes, mostly in the resort community of Summerhaven, according to news reports. These data are being used by NASA's Wildfire Response Team and the US Forest Service to assess the intensity of the burn for future remediation efforts. This image was acquired on June 26, 2003 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on Terra. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet. http://photojournal.jpl.nasa.gov/catalog/PIA04602

  9. Satellite passive microwave detection of surface water inundation changes over the pan-Arctic from AMSR

    NASA Astrophysics Data System (ADS)

    Du, J.; Kimball, J. S.; Jones, L. A.; Watts, J. D.

    2016-12-01

    Climate is one of the key drivers of crop suitability and productivity in a region. The influence of climate and weather on the growing season determine the amount of time crops spend in each growth phase, which in turn impacts productivity and, more importantly, yields. Planting date can have a strong influence on yields with earlier planting generally resulting in higher yields, a sensitivity that is also present in some crop models. Furthermore, planting date is already changing and may continue, especially if longer growing seasons caused by future climate change drive early (or late) planting decisions. Crop models need an accurate method to predict plant date to allow these models to: 1) capture changes in crop management to adapt to climate change, 2) accurately model the timing of crop phenology, and 3) improve crop simulated influences on carbon, nutrient, energy, and water cycles. Previous studies have used climate as a predictor for planting date. Climate as a plant date predictor has more advantages than fixed plant dates. For example, crop expansion and other changes in land use (e.g., due to changing temperature conditions), can be accommodated without additional model inputs. As such, a new methodology to implement a predictive planting date based on climate inputs is added to the Accelerated Climate Model for Energy (ACME) Land Model (ALM). The model considers two main sources of climate data important for planting: precipitation and temperature. This method expands the current temperature threshold planting trigger and improves the estimated plant date in ALM. Furthermore, the precipitation metric for planting, which synchronizes the crop growing season with the wettest months, allows tropical crops to be introduced to the model. This presentation will demonstrate how the improved model enhances the ability of ALM to capture planting date compared with observations. More importantly, the impact of changing the planting date and introducing tropical crops will be explored. Those impacts include discussions on productivity, yield, and influences on carbon and energy fluxes.

  10. Geometric and computer-aided spline hob modeling

    NASA Astrophysics Data System (ADS)

    Brailov, I. G.; Myasoedova, T. M.; Panchuk, K. L.; Krysova, I. V.; Rogoza, YU A.

    2018-03-01

    The paper considers acquiring the spline hob geometric model. The objective of the research is the development of a mathematical model of spline hob for spline shaft machining. The structure of the spline hob is described taking into consideration the motion in parameters of the machine tool system of cutting edge positioning and orientation. Computer-aided study is performed with the use of CAD and on the basis of 3D modeling methods. Vector representation of cutting edge geometry is accepted as the principal method of spline hob mathematical model development. The paper defines the correlations described by parametric vector functions representing helical cutting edges designed for spline shaft machining with consideration for helical movement in two dimensions. An application for acquiring the 3D model of spline hob is developed on the basis of AutoLISP for AutoCAD environment. The application presents the opportunity for the use of the acquired model for milling process imitation. An example of evaluation, analytical representation and computer modeling of the proposed geometrical model is reviewed. In the mentioned example, a calculation of key spline hob parameters assuring the capability of hobbing a spline shaft of standard design is performed. The polygonal and solid spline hob 3D models are acquired by the use of imitational computer modeling.

  11. Alpha-fetoprotein-targeted reporter gene expression imaging in hepatocellular carcinoma.

    PubMed

    Kim, Kwang Il; Chung, Hye Kyung; Park, Ju Hui; Lee, Yong Jin; Kang, Joo Hyun

    2016-07-21

    Hepatocellular carcinoma (HCC) is one of the most common cancers in Eastern Asia, and its incidence is increasing globally. Numerous experimental models have been developed to better our understanding of the pathogenic mechanism of HCC and to evaluate novel therapeutic approaches. Molecular imaging is a convenient and up-to-date biomedical tool that enables the visualization, characterization and quantification of biologic processes in a living subject. Molecular imaging based on reporter gene expression, in particular, can elucidate tumor-specific events or processes by acquiring images of a reporter gene's expression driven by tumor-specific enhancers/promoters. In this review, we discuss the advantages and disadvantages of various experimental HCC mouse models and we present in vivo images of tumor-specific reporter gene expression driven by an alpha-fetoprotein (AFP) enhancer/promoter system in a mouse model of HCC. The current mouse models of HCC development are established by xenograft, carcinogen induction and genetic engineering, representing the spectrum of tumor-inducing factors and tumor locations. The imaging analysis approach of reporter genes driven by AFP enhancer/promoter is presented for these different HCC mouse models. Such molecular imaging can provide longitudinal information about carcinogenesis and tumor progression. We expect that clinical application of AFP-targeted reporter gene expression imaging systems will be useful for the detection of AFP-expressing HCC tumors and screening of increased/decreased AFP levels due to disease or drug treatment.

  12. Alpha-fetoprotein-targeted reporter gene expression imaging in hepatocellular carcinoma

    PubMed Central

    Kim, Kwang Il; Chung, Hye Kyung; Park, Ju Hui; Lee, Yong Jin; Kang, Joo Hyun

    2016-01-01

    Hepatocellular carcinoma (HCC) is one of the most common cancers in Eastern Asia, and its incidence is increasing globally. Numerous experimental models have been developed to better our understanding of the pathogenic mechanism of HCC and to evaluate novel therapeutic approaches. Molecular imaging is a convenient and up-to-date biomedical tool that enables the visualization, characterization and quantification of biologic processes in a living subject. Molecular imaging based on reporter gene expression, in particular, can elucidate tumor-specific events or processes by acquiring images of a reporter gene’s expression driven by tumor-specific enhancers/promoters. In this review, we discuss the advantages and disadvantages of various experimental HCC mouse models and we present in vivo images of tumor-specific reporter gene expression driven by an alpha-fetoprotein (AFP) enhancer/promoter system in a mouse model of HCC. The current mouse models of HCC development are established by xenograft, carcinogen induction and genetic engineering, representing the spectrum of tumor-inducing factors and tumor locations. The imaging analysis approach of reporter genes driven by AFP enhancer/promoter is presented for these different HCC mouse models. Such molecular imaging can provide longitudinal information about carcinogenesis and tumor progression. We expect that clinical application of AFP-targeted reporter gene expression imaging systems will be useful for the detection of AFP-expressing HCC tumors and screening of increased/decreased AFP levels due to disease or drug treatment. PMID:27468205

  13. Influence of real-world characteristics on outcomes for patients with methicillin-resistant Staphylococcal skin and soft tissue infections: a multi-country medical chart review in Europe.

    PubMed

    Nathwani, Dilip; Eckmann, Christian; Lawson, Wendy; Solem, Caitlyn T; Corman, Shelby; Stephens, Jennifer M; Macahilig, Cynthia; Simoneau, Damien; Chambers, Richard; Li, Jim Z; Haider, Seema

    2014-09-02

    Patient-related (demographic/disease) and treatment-related (drug/clinician/hospital) characteristics were evaluated as potential predictors of healthcare resource use and opportunities for early switch (ES) from intravenous (IV)-to-oral methicillin-resistant Staphylococcus aureus (MRSA)-active antibiotic therapy and early hospital discharge (ED). This retrospective observational medical chart study analyzed patients (across 12 European countries) with microbiologically confirmed MRSA complicated skin and soft tissue infections (cSSTI), ≥3 days of IV anti-MRSA antibiotics during hospitalization (July 1, 2010-June 30, 2011), and discharged alive by July 31, 2011. Logistic/linear regression models evaluated characteristics potentially associated with actual resource use (length of IV therapy, length of hospital stay [LOS], IV-to-oral antibiotic switch), and ES and ED (using literature-based and expert-verified criteria) outcomes. 1542 patients (mean ± SD age 60.8 ± 16.5 years; 61.5% males) were assessed with 81.0% hospitalized for MRSA cSSTI as the primary reason. Several patient demographic, infection, complication, treatment, and hospital characteristics were predictive of length of IV therapy, LOS, IV-to-oral antibiotic switch, or ES and ED opportunities. Outcomes and ES and ED opportunities varied across countries. Length of IV therapy and LOS (r = 0.66, p < 0.0001) and eligibilities for ES and ED (r = 0.44, p < 0.0001) showed relatively strong correlations. IV-to-oral antibiotic switch patients had significantly shorter length of IV therapy (-5.19 days, p < 0.001) and non-significantly shorter LOS (-1.86 days, p > 0.05). Certain patient and treatment characteristics were associated with increased odds of ES (healthcare-associated/ hospital-acquired infection) and ED (patient living arrangements, healthcare-associated/ hospital-acquired infection, initiating MRSA-active treatment 1-2 days post cSSTI index date, existing ED protocol), while other factors decreased the odds of ES (no documented MRSA culture, ≥4 days from admission to cSSTI index date, IV-to-oral switch, IV line infection) and ED (dementia, no documented MRSA culture, initiating MRSA-active treatment ≥3 days post cSSTI index date, existing ES protocol). Practice patterns and opportunity for further ES and ED were affected by several infection, treatment, hospital, and geographical characteristics, which should be considered in identifying ES and ED opportunities and designing interventions for MRSA cSSTI to reduce IV days and LOS while maintaining the quality of care.

  14. Using Landsat to provide potato production estimates to Columbia Basin farmers and processors

    NASA Technical Reports Server (NTRS)

    1990-01-01

    A summary of project activities relative to the estimation of potato yields in the Columbia Basin is given. Oregon State University is using a two-pronged approach to yield estimation, one using simulation models and the other using purely empirical models. The simulation modeling approach has used satellite observations to determine key dates in the development of the crop for each field identified as potatoes. In particular, these include planting dates, emergence dates, and harvest dates. These critical dates are fed into simulation models of crop growth and development to derive yield forecasts. Two empirical modeling approaches are illustrated. One relates tuber yield to estimates of cumulative intercepted solar radiation; the other relates tuber yield to the integral under the GVI curve.

  15. Exploiting a Molecular Gleason Grade for Prostate Cancer Therapy

    DTIC Science & Technology

    2008-03-01

    influenced by epigenetic events. Through comprehensive studies of genome and gene expression alterations, it is clear that prostate cancers are...recognizing grade-determinant proteins (months 1-12). To date, we have purchased (or acquired) antibodies recognizing; TMPRSS2, MAOA , DAD1, ERG, Jagged...and neoplastic prostate cases: TMPRSS2, MAOA , DAD1, ERG, Jagged, p63, AMACR, MUC1, FLNA, ALSCR2, CCNG2, FLH2, GSTMU1, PC4, RSK2, and SMS—see reportable

  16. Brain Computer Interfaces for Enhanced Interaction with Mobile Robot Agents

    DTIC Science & Technology

    2016-07-27

    synergistic and complementary way. This project focused on acquiring a mobile robotic agent platform that can be used to explore these interfaces...providing a test environment where the human control of a robot agent can be experimentally validated in 1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND...Distribution Unlimited UU UU UU UU 27-07-2016 17-Sep-2013 16-Sep-2014 Final Report: Brain Computer Interfaces for Enhanced Interactions with Mobile Robot

  17. Planetary Analogs in Antarctica: Icy Satellites

    NASA Technical Reports Server (NTRS)

    Malin, M. C.

    1985-01-01

    As part of a study to provide semi-quantitative techniques to date past Antarctic glaciations, sponsored by the Antarctic Research Program, field observations pertinent to other planets were also acquired. The extremely diverse surface conditions, marked by extreme cold and large amounts of ice, provide potential terrain and process analogs to the icy satellites of Jupiter and Saturn. Thin ice tectonic features and explosion craters (on sea ice) and deformation features on thicker ice (glaciers) are specifically addressed.

  18. 4D very high-resolution topography monitoring of surface deformation using UAV-SfM framework.

    NASA Astrophysics Data System (ADS)

    Clapuyt, François; Vanacker, Veerle; Schlunegger, Fritz; Van Oost, Kristof

    2016-04-01

    During the last years, exploratory research has shown that UAV-based image acquisition is suitable for environmental remote sensing and monitoring. Image acquisition with cameras mounted on an UAV can be performed at very-high spatial resolution and high temporal frequency in the most dynamic environments. Combined with Structure-from-Motion algorithm, the UAV-SfM framework is capable of providing digital surface models (DSM) which are highly accurate when compared to other very-high resolution topographic datasets and highly reproducible for repeated measurements over the same study area. In this study, we aim at assessing (1) differential movement of the Earth's surface and (2) the sediment budget of a complex earthflow located in the Central Swiss Alps based on three topographic datasets acquired over a period of 2 years. For three time steps, we acquired aerial photographs with a standard reflex camera mounted on a low-cost and lightweight UAV. Image datasets were then processed with the Structure-from-Motion algorithm in order to reconstruct a 3D dense point cloud representing the topography. Georeferencing of outputs has been achieved based on the ground control point (GCP) extraction method, previously surveyed on the field with a RTK GPS. Finally, digital elevation model of differences (DOD) has been computed to assess the topographic changes between the three acquisition dates while surface displacements have been quantified by using image correlation techniques. Our results show that the digital elevation model of topographic differences is able to capture surface deformation at cm-scale resolution. The mean annual displacement of the earthflow is about 3.6 m while the forefront of the landslide has advanced by ca. 30 meters over a period of 18 months. The 4D analysis permits to identify the direction and velocity of Earth movement. Stable topographic ridges condition the direction of the flow with highest downslope movement on steep slopes, and diffuse movement due to lateral sediment flux in the central part of the earthflow.

  19. Georeferencing UAS Derivatives Through Point Cloud Registration with Archived Lidar Datasets

    NASA Astrophysics Data System (ADS)

    Magtalas, M. S. L. Y.; Aves, J. C. L.; Blanco, A. C.

    2016-10-01

    Georeferencing gathered images is a common step before performing spatial analysis and other processes on acquired datasets using unmanned aerial systems (UAS). Methods of applying spatial information to aerial images or their derivatives is through onboard GPS (Global Positioning Systems) geotagging, or through tying of models through GCPs (Ground Control Points) acquired in the field. Currently, UAS (Unmanned Aerial System) derivatives are limited to meter-levels of accuracy when their generation is unaided with points of known position on the ground. The use of ground control points established using survey-grade GPS or GNSS receivers can greatly reduce model errors to centimeter levels. However, this comes with additional costs not only with instrument acquisition and survey operations, but also in actual time spent in the field. This study uses a workflow for cloud-based post-processing of UAS data in combination with already existing LiDAR data. The georeferencing of the UAV point cloud is executed using the Iterative Closest Point algorithm (ICP). It is applied through the open-source CloudCompare software (Girardeau-Montaut, 2006) on a `skeleton point cloud'. This skeleton point cloud consists of manually extracted features consistent on both LiDAR and UAV data. For this cloud, roads and buildings with minimal deviations given their differing dates of acquisition are considered consistent. Transformation parameters are computed for the skeleton cloud which could then be applied to the whole UAS dataset. In addition, a separate cloud consisting of non-vegetation features automatically derived using CANUPO classification algorithm (Brodu and Lague, 2012) was used to generate a separate set of parameters. Ground survey is done to validate the transformed cloud. An RMSE value of around 16 centimeters was found when comparing validation data to the models georeferenced using the CANUPO cloud and the manual skeleton cloud. Cloud-to-cloud distance computations of CANUPO and manual skeleton clouds were obtained with values for both equal to around 0.67 meters at 1.73 standard deviation.

  20. The Morphology of the Rat Vibrissal Array: A Model for Quantifying Spatiotemporal Patterns of Whisker-Object Contact

    PubMed Central

    Gopal, Venkatesh; Solomon, Joseph H.; Hartmann, Mitra J. Z.

    2011-01-01

    In all sensory modalities, the data acquired by the nervous system is shaped by the biomechanics, material properties, and the morphology of the peripheral sensory organs. The rat vibrissal (whisker) system is one of the premier models in neuroscience to study the relationship between physical embodiment of the sensor array and the neural circuits underlying perception. To date, however, the three-dimensional morphology of the vibrissal array has not been characterized. Quantifying array morphology is important because it directly constrains the mechanosensory inputs that will be generated during behavior. These inputs in turn shape all subsequent neural processing in the vibrissal-trigeminal system, from the trigeminal ganglion to primary somatosensory (“barrel”) cortex. Here we develop a set of equations for the morphology of the vibrissal array that accurately describes the location of every point on every whisker to within ±5% of the whisker length. Given only a whisker's identity (row and column location within the array), the equations establish the whisker's two-dimensional (2D) shape as well as three-dimensional (3D) position and orientation. The equations were developed via parameterization of 2D and 3D scans of six rat vibrissal arrays, and the parameters were specifically chosen to be consistent with those commonly measured in behavioral studies. The final morphological model was used to simulate the contact patterns that would be generated as a rat uses its whiskers to tactually explore objects with varying curvatures. The simulations demonstrate that altering the morphology of the array changes the relationship between the sensory signals acquired and the curvature of the object. The morphology of the vibrissal array thus directly constrains the nature of the neural computations that can be associated with extraction of a particular object feature. These results illustrate the key role that the physical embodiment of the sensor array plays in the sensing process. PMID:21490724

  1. The accuracy of ultrashort echo time MRI sequences for medical additive manufacturing.

    PubMed

    van Eijnatten, Maureen; Rijkhorst, Erik-Jan; Hofman, Mark; Forouzanfar, Tymour; Wolff, Jan

    2016-01-01

    Additively manufactured bone models, implants and drill guides are becoming increasingly popular amongst maxillofacial surgeons and dentists. To date, such constructs are commonly manufactured using CT technology that induces ionizing radiation. Recently, ultrashort echo time (UTE) MRI sequences have been developed that allow radiation-free imaging of facial bones. The aim of the present study was to assess the feasibility of UTE MRI sequences for medical additive manufacturing (AM). Three morphologically different dry human mandibles were scanned using a CT and MRI scanner. Additionally, optical scans of all three mandibles were made to acquire a "gold standard". All CT and MRI scans were converted into Standard Tessellation Language (STL) models and geometrically compared with the gold standard. To quantify the accuracy of the AM process, the CT, MRI and gold-standard STL models of one of the mandibles were additively manufactured, optically scanned and compared with the original gold-standard STL model. Geometric differences between all three CT-derived STL models and the gold standard were <1.0 mm. All three MRI-derived STL models generally presented deviations <1.5 mm in the symphyseal and mandibular area. The AM process introduced minor deviations of <0.5 mm. This study demonstrates that MRI using UTE sequences is a feasible alternative to CT in generating STL models of the mandible and would therefore be suitable for surgical planning and AM. Further in vivo studies are necessary to assess the usability of UTE MRI sequences in clinical settings.

  2. Linear diffusion model dating of cinder cones in Central Anatolia, Turkey

    NASA Astrophysics Data System (ADS)

    O'Sadnick, L. G.; Reid, M. R.; Cline, M. L.; Cosca, M. A.; Kuscu, G.

    2013-12-01

    The progressive decrease in slope angle, cone height and cone height/width ratio over time provides the basis for geomorphic dating of cinder cones using linear diffusion models. Previous research using diffusion models to date cinder cones has focused on the cone height/width ratio as the basis for dating cones of unknown age [1,2]. Here we apply linear diffusion models to dating cinder cones. A suite of 16 cinder cones from the Hasandağ volcano area of the Neogene-Quaternary Central Anatolian Volcanic Zone, for which samples are available, were selected for morphologic dating analysis. New 40Ar/39Ar dates for five of these cones range from 62 × 4 to 517 × 9 ka. Linear diffusion models were used to model the erosional degradation of each cone. Diffusion coefficients (κ) for the 5 cinder cones with known ages were constrained by comparing various modeled slope profiles to the current slope profile. The resulting κ is 7.5×0.5 m2kyr-1. Using this κ value, eruption ages were modeled for the remaining 11 cinder cones and range from 53×3 to 455×30 ka. These ages are within the range of ages previously reported for cinder cones in the Hasandağ region. The linear diffusion model-derived ages are being compared to additional new 40Ar/39Ar dates in order to further assess the applicability of morphological dating to constrain the ages of cinder cones. The relatively well-constrained κ value we obtained by applying the linear diffusion model to cinder cones that range in age by nearly 500 ka suggests that this model can be used to date cinder cones. This κ value is higher than the well-established value of κ =3.9 for a cinder cone in a similar climate [3]. Therefore our work confirms the importance of determining appropriate κ values from nearby cones with known ages. References 1. C.A. Wood, J. Volcanol. Geotherm. Res. 8, 137 (1980) 2. D.M. Wood, M.F. Sheridan, J. Volcanol. Geotherm. Res. 83, 241 (1998) 3. J.D. Pelletier, M.L. Cline, Geology 35, 1067 (2007)

  3. The relationship between social support and adolescent dating violence: a comparison across genders.

    PubMed

    Richards, Tara N; Branch, Kathryn A

    2012-05-01

    Although much research has focused on the function of social support in adult intimate partner violence, little is known about the role of social support in adolescent dating violence. This study is an exploratory analysis of the independent impact of social support from friends and family on the risk of adolescent dating violence perpetration and victimization among a large sample of youth (n = 970). Approximately, 21% of the sample reported experiencing victimization in a dating relationship whereas 23% indicated perpetrating dating violence. Male youth reported significantly more involvement in dating violence as both perpetrators and victims. Negative binomial regression modeling indicated that increased levels of support from friends was associated with significantly less dating violence perpetration and victimization; however, when gendered models were explored, the protective role of social support was only maintained for female youth. Family support was not significantly related to dating violence in any model. Implications for dating violence curriculum and future research are addressed.

  4. Marine evidence of a deconvolving Antarctic Ice Sheet during post-LGM retreat of the Ross Sea sector

    NASA Astrophysics Data System (ADS)

    Prothro, L. O.; Yokoyama, Y.; Simkins, L. M.; Anderson, J. B.; Majewski, W.; Yamane, M.; Ohkouchi, N.

    2017-12-01

    Predictive models of ice sheet and sea level change are dependent on observational data of ice-sheet behavior for model testing and tuning. The geologic record contains a wealth of information about ice-sheet dynamics, with fewer logistical, spatial, and temporal limitations than are involved in data acquisition along contemporary ice margins. However, past ice-sheet behavior is still largely uncertain or contested due to issues with obtaining meaningful radiocarbon dates. We minimize bias from glacially-reworked carbon and limitations from unknown geomorphic context and uncertainty in sediment facies identification by using careful sedimentary analyses within a geomorphic framework, as well as selection of appropriate dating methods. Our study area, the Ross Sea sector of Antarctica, is the primary drainage outlet for 25% of the continent's grounded ice. During the Last Glacial Maximum, the low-profile, marine-based West Antarctic Ice Sheet (WAIS) and the steeper profile, largely land-based East Antarctic Ice Sheet (EAIS) converged in the Ross Sea to flow out to or near the continental shelf edge. Geomorphic and sedimentary data reveal that during their subsequent retreat to form the Ross Sea Embayment, the two ice sheets behaved differently, with the WAIS rapidly retreating tens of kilometers followed by extended pauses, while the EAIS retreated steadily, with shorter (decadal- to century-long) pauses. This behavior leads us to believe that the two ice sheets may have contributed diachronously to sea level. By acquiring accurate timing of grounding line retreat, we are able to calculate volumes of ice lost throughout deglaciation, as well as associated sea level contributions. In addition, we attempt to rectify the contradicting marine and terrestrial interpretations of retreat patterns from the Ross Sea continental shelf.

  5. Computational analysis of high resolution unsteady airloads for rotor aeroacoustics

    NASA Technical Reports Server (NTRS)

    Quackenbush, Todd R.; Lam, C.-M. Gordon; Wachspress, Daniel A.; Bliss, Donald B.

    1994-01-01

    The study of helicopter aerodynamic loading for acoustics applications requires the application of efficient yet accurate simulations of the velocity field induced by the rotor's vortex wake. This report summarizes work to date on the development of such an analysis, which builds on the Constant Vorticity Contour (CVC) free wake model, previously implemented for the study of vibratory loading in the RotorCRAFT computer code. The present effort has focused on implementation of an airload reconstruction approach that computes high resolution airload solutions of rotor/rotor-wake interactions required for acoustics computations. Supplementary efforts on the development of improved vortex core modeling, unsteady aerodynamic effects, higher spatial resolution of rotor loading, and fast vortex wake implementations have substantially enhanced the capabilities of the resulting software, denoted RotorCRAFT/AA (AeroAcoustics). Results of validation calculations using recently acquired model rotor data show that by employing airload reconstruction it is possible to apply the CVC wake analysis with temporal and spatial resolution suitable for acoustics applications while reducing the computation time required by one to two orders of magnitude relative to that required by direct calculations. Promising correlation with this body of airload and noise data has been obtained for a variety of rotor configurations and operating conditions.

  6. Pneumococcal vaccination reduces the risk of community-acquired pneumonia in children.

    PubMed

    Hasegawa, Junko; Mori, Mitsuru; Ohnishi, Hirofumi; Tsugawa, Takeshi; Hori, Tsukasa; Yoto, Yuko; Tsutsumi, Hiroyuki

    2017-03-01

    The seven-valent pneumococcal conjugate vaccine (PCV7) was introduced to Japan in 2009, after which there was a rapid decline in invasive pneumococcal disease. There are few data, however, on the effectiveness of PCV7 against community-acquired pneumonia (CAP). We conducted an ambispective cohort study among children aged 0-6 years old who attended day-care centers. A total of 624 children at 10 day-care centers in Sapporo, Japan participated in the study. The parents reported whether their child had received PCV7 one or more times, as well as the exact dates of vaccination from records in maternal and child health handbooks marked by pediatricians. Each CAP event was reported by parents according to doctor diagnosis. A Cox proportional hazards regression model was used to calculate the hazard ratio (HR) and 95%CI of CAP incidence reduced by PCV7 inoculation. During the observational period, 94 subjects contracted CAP. After adjusting for potentially confounding variables, inoculation with PCV7 was significantly associated with a reduced risk of CAP (HR, 0.22; 95%CI: 0.13-0.34). On stratified analysis by age, PCV7 was significantly associated with a reduced risk of CAP in both children aged <3 years (HR, 0.31; 95%CI: 0.14-0.71), and those ≥3 years (HR, 0.20; 95%CI: 0.09-0.43). PCV7 is highly effective in reducing the risk of CAP in children attending day-care centers. © 2016 Japan Pediatric Society.

  7. VizieR Online Data Catalog: 280 one-opposition near Earth asteroids (Vaduvescu+, 2018)

    NASA Astrophysics Data System (ADS)

    Vaduvescu, O.; Hudin, L.; Mocnik, T.; Char, F.; Sonka, A.; Tudor, V.; Ordonez-Etxeberria, I.; Diaz Alfaro, M.; Ashley, R.; Errmann, R.; Short, P.; Moloceniuc, A.; Cornea, R.; Inceu, V.; Zavoianu, D.; Popescu, M.; Curelaru, L.; Mihalea, S.; Stoian, A.-M.; Boldea, A.; Toma, R.; Fields, L.; Grigore, V.; Stoev, H.; Lopez-Martinez, F.; Humphries, N.; Sowicka, P.; Ramanjooloo, Y.; Manilla-Robles, A.; Riddick, F. C.; Jimenez-Lujan, F.; Mendez, J.; Aceituno, F.; Sota, A.; Jones, D.; Hidalgo, S.; Murabito, S.; Oteo, I.; Bongiovanni, A.; Zamora, O.; Pyrzas, S.; Tanausu, R.; Font, J.; Bereciartua, A.; Perez-Fournon, I.; Martinez-Vazquez, C. E.; Monelli, M.; Cicuendez, L.; Monteagudo, L.; Agulli, I.; Bouy, H.; Huelamo, N.; Monguio, M.; Gaensicke, B. T.; Steeghs, D.; Gentile-Fusillo, N. P.; Hollands, M. A.; Toloza, O.; Manser, C. J.; Dhillon, V.; Sahman, D.; Fitzsimmons, A.; McNeill, A.; Thompson, A.; Tabor, M.; Murphy, D. N. A.; Davies, J.; Snodgrass, C.; Triaud, A. H. M. J.; Groot, P. J.; Macfarlane, S.; Peletier, R.; Sen, S.; Ikiz, T.; Hoekstra, H.; Herbonnet, R.; Koehlinger, F.; Greimel, R.; Afonso, A.; Parker, Q. A.; Kong, A. K. H.; Bassa, C.; Pleunis, Z.

    2017-10-01

    Table 2 lists the observing log of the EURONEAR 2013-2016 one-opposition near Earth asteroids (NEAs) recovery project. The Tables includes 457 observed fields (437 using the INT, 12 using the WHT and 4 using the OGS). We ordered the table based on the asteroid designation (first column) then the observing date (start night), listing the apparent magnitude V (according to MPC ephemerides), the proper motion miu and the positional uncertainty of the targets (as shown on the observing date by MPC at 3σ level), the number of acquired images (including nearby fields), and the exposure time (in seconds). In the last three columns we list the current status of the targets (as classified in the paper by Aug 2017), the MPS publication that includes our recovery, and some comments that can include the PHA classification, other used telescopes (WHT or OGS), the track-and-stack technique (TS, whenever used), other possible external stations (MPC observatory code) and the date of later recovery (given only for later recoveries when we were unable to find the targets or for joined simultaneous recoveries). (1 data file).

  8. Mapping and spatial-temporal modeling of Bromus tectorum invasion in central Utah

    NASA Astrophysics Data System (ADS)

    Jin, Zhenyu

    Cheatgrass, or Downy Brome, is an exotic winter annual weed native to the Mediterranean region. Since its introduction to the U.S., it has become a significant weed and aggressive invader of sagebrush, pinion-juniper, and other shrub communities, where it can completely out-compete native grasses and shrubs. In this research, remotely sensed data combined with field collected data are used to investigate the distribution of the cheatgrass in Central Utah, to characterize the trend of the NDVI time-series of cheatgrass, and to construct a spatially explicit population-based model to simulate the spatial-temporal dynamics of the cheatgrass. This research proposes a method for mapping the canopy closure of invasive species using remotely sensed data acquired at different dates. Different invasive species have their own distinguished phenologies and the satellite images in different dates could be used to capture the phenology. The results of cheatgrass abundance prediction have a good fit with the field data for both linear regression and regression tree models, although the regression tree model has better performance than the linear regression model. To characterize the trend of NDVI time-series of cheatgrass, a novel smoothing algorithm named RMMEH is presented in this research to overcome some drawbacks of many other algorithms. By comparing the performance of RMMEH in smoothing a 16-day composite of the MODIS NDVI time-series with that of two other methods, which are the 4253EH, twice and the MVI, we have found that RMMEH not only keeps the original valid NDVI points, but also effectively removes the spurious spikes. The reconstructed NDVI time-series of different land covers are of higher quality and have smoother temporal trend. To simulate the spatial-temporal dynamics of cheatgrass, a spatially explicit population-based model is built applying remotely sensed data. The comparison between the model output and the ground truth of cheatgrass closure demonstrates that the model could successfully simulate the spatial-temporal dynamics of cheatgrass in a simple cheatgrass-dominant environment. The simulation of the functional response of different prescribed fire rates also shows that this model is helpful to answer management questions like, "What are the effects of prescribed fire to invasive species?" It demonstrates that a medium fire rate of 10% can successfully prevent cheatgrass invasion.

  9. Sexual communication between early adolescents and their dating partners, parents, and best friends.

    PubMed

    Widman, Laura; Choukas-Bradley, Sophia; Helms, Sarah W; Golin, Carol E; Prinstein, Mitchell J

    2014-01-01

    This study assessed early adolescents' sexual communication with dating partners, parents, and best friends about six sexual health topics: condoms, birth control, sexually transmitted diseases (STDs), human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), pregnancy, and abstinence/waiting. Using a school-based sample of 603 youth (ages 12 to 15; 57% female; 46% Caucasian), we examined communication differences across demographic and developmental factors, tested whether communication with parents and best friends was associated with greater communication with partners, and examined associations between communication and condom use. More than half of participants had not discussed any sexual topics with their dating partners (54%), and many had not communicated with parents (29%) or best friends (25%). On average, communication was more frequent among adolescents who were female, African American, older, and sexually active, despite some variation in subgroups across partner, parent, and friend communication. Importantly, communication with parents and friends--and the interaction between parent and friend communication--was associated with increased communication with dating partners. Further, among sexually active youth, increased sexual communication with partners was associated with more frequent condom use. Results highlight the importance of understanding the broader family and peer context surrounding adolescent sexual decision making and suggest a possible need to tailor sexual communication interventions.

  10. Using LANDSAT to provide potato production estimates to Columbia Basin farmers and processors

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The estimation of potato yields in the Columbia basin is described. The fundamental objective is to provide CROPIX with working models of potato production. A two-pronged approach was used to yield estimation: (1) using simulation models, and (2) using purely empirical models. The simulation modeling approach used satellite observations to determine certain key dates in the development of the crop for each field identified as potatoes. In particular, these include planting dates, emergence dates, and harvest dates. These critical dates are fed into simulation models of crop growth and development to derive yield forecasts. Purely empirical models were developed to relate yield to some spectrally derived measure of crop development. Two empirical approaches are presented: one relates tuber yield to estimates of cumulative intercepted solar radiation, the other relates tuber yield to the integral under GVI (Global Vegetation Index) curve.

  11. Paroxysmal sympathetic hyperactivity: An entity to keep in mind.

    PubMed

    Godoy, D A; Panhke, P; Guerrero Suarez, P D; Murillo-Cabezas, F

    2017-12-15

    Paroxysmal sympathetic hyperactivity (PSH) is a potentially life-threatening neurological emergency secondary to multiple acute acquired brain injuries. It is clinically characterized by the cyclic and simultaneous appearance of signs and symptoms secondary to exacerbated sympathetic discharge. The diagnosis is based on the clinical findings, and high alert rates are required. No widely available and validated homogeneous diagnostic criteria have been established to date. There have been recent consensus attempts to shed light on this obscure phenomenon. Its physiopathology is complex and has not been fully clarified. However, the excitation-inhibition model is the theory that best explains the different aspects of this condition, including the response to treatment with the available drugs. The key therapeutic references are the early recognition of the disorder, avoiding secondary injuries and the triggering of paroxysms. Once sympathetic crises occur, they must peremptorily aborted and prevented. of the later the syndrome is recognized, the poorer the patient outcome. Copyright © 2017 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  12. Estimation of Lithological Classification in Taipei Basin: A Bayesian Maximum Entropy Method

    NASA Astrophysics Data System (ADS)

    Wu, Meng-Ting; Lin, Yuan-Chien; Yu, Hwa-Lung

    2015-04-01

    In environmental or other scientific applications, we must have a certain understanding of geological lithological composition. Because of restrictions of real conditions, only limited amount of data can be acquired. To find out the lithological distribution in the study area, many spatial statistical methods used to estimate the lithological composition on unsampled points or grids. This study applied the Bayesian Maximum Entropy (BME method), which is an emerging method of the geological spatiotemporal statistics field. The BME method can identify the spatiotemporal correlation of the data, and combine not only the hard data but the soft data to improve estimation. The data of lithological classification is discrete categorical data. Therefore, this research applied Categorical BME to establish a complete three-dimensional Lithological estimation model. Apply the limited hard data from the cores and the soft data generated from the geological dating data and the virtual wells to estimate the three-dimensional lithological classification in Taipei Basin. Keywords: Categorical Bayesian Maximum Entropy method, Lithological Classification, Hydrogeological Setting

  13. HST/WFC3 flux calibration ladder: Vega

    NASA Astrophysics Data System (ADS)

    Deustua, Susana E.; Bohlin, Ralph; Pirzkal, Nor; MacKenty, John

    2014-08-01

    Vega is one of only a few stars calibrated against an SI-traceable blackbody, and is the historical flux standard. Photometric zeropoints of the Hubble Space Telescope's instruments rely on Vega, through the transfer of its calibration via stellar atmosphere models to the suite of standard stars. HST's recently implemented scan mode has enabled us to develop a path to an absolute SI traceable calibration for HST IR observations. To fill in the crucial gap between 0.9 and 1.7 micron in the absolute calibration, we acquired -1st order spectra of Vega with the two WFC3 infrared grisms. At the same time, we have improved the calibration of the -1st orders of both WFC3 IR grisms, as well as extended the dynamic range of WFC3 science observations by a factor of 10000. We describe our progress to date on the WFC3 `flux calibration ladder' project to provide currently needed accurate zeropoint measurements in the IR

  14. Landsat-8 Operational Land Imager On-Orbit Radiometric Calibration

    NASA Technical Reports Server (NTRS)

    Markham, Brian L.; Barsi, Julia A.

    2017-01-01

    The Operational Land Imager (OLI), the VIS/NIR/SWIR sensor on the Landsat-8 has been successfully acquiring Earth Imagery for more than four years. The OLI incorporates two on-board radiometric calibration systems, one diffuser based and one lamp based, each with multiple sources. For each system one source is treated as primary and used frequently and the other source(s) are used less frequently to assist in tracking any degradation in the primary sources. In addition, via a spacecraft maneuver, the OLI instrument views the moon once a lunar cycle (approx. 29 days). The integrated lunar irradiances from these acquisitions are compared to the output of a lunar irradiance model. The results from all these techniques, combined with cross calibrations with other sensors and ground based vicarious measurements are used to monitor the OLI's stability and correct for any changes observed. To date, the various techniques have other detected significant changes in the shortest wavelength OLI band centered at 443 nm and these are currently being adjusted in the operational processing.

  15. Strict tropism for CD71+/CD234+ human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi

    PubMed Central

    Kosaisavee, Varakorn; Suwanarusk, Rossarin; Chua, Adeline C. Y.; Kyle, Dennis E.; Malleret, Benoit; Zhang, Rou; Imwong, Mallika; Imerbsin, Rawiwan; Ubalee, Ratawan; Sámano-Sánchez, Hugo; Yeung, Bryan K. S.; Ong, Jessica J. Y.; Lombardini, Eric; Nosten, François; Tan, Kevin S. W.; Bifani, Pablo; Snounou, Georges; Rénia, Laurent

    2017-01-01

    Two malaria parasites of Southeast Asian macaques, Plasmodium knowlesi and P cynomolgi, can infect humans experimentally. In Malaysia, where both species are common, zoonotic knowlesi malaria has recently become dominant, and cases are recorded throughout the region. By contrast, to date, only a single case of naturally acquired P cynomolgi has been found in humans. In this study, we show that whereas P cynomolgi merozoites invade monkey red blood cells indiscriminately in vitro, in humans, they are restricted to reticulocytes expressing both transferrin receptor 1 (Trf1 or CD71) and the Duffy antigen/chemokine receptor (DARC or CD234). This likely contributes to the paucity of detectable zoonotic cynomolgi malaria. We further describe postinvasion morphologic and rheologic alterations in P cynomolgi–infected human reticulocytes that are strikingly similar to those observed for P vivax. These observations stress the value of P cynomolgi as a model in the development of blood stage vaccines against vivax malaria. PMID:28698207

  16. [The role of microRNAs in head and neck squamous cell carcinoma : Biomarkers for prognosis, therapy selection, and novel therapeutics].

    PubMed

    Heß, A K; Weichert, W; Budach, V; Tinhofer, I

    2016-05-01

    Despite recent advances in radiochemotherapy, treatment of locally advanced head and neck squamous cell carcinoma is still challenging, and survival rates have improved only slightly. This is due to the high frequency of metastases and local and/or regional tumor recurrences that have acquired radio- or chemoresistance. MiRNAs regulate diverse processes in tumorigenesis, metastasis, and therapy resistance in head and neck squamous cell carcinoma. Hence, miRNAs are highly valued in biomarker studies. Establishment of the miRNA profiles of oropharyngeal tumors enables personalized treatment selection, since expression of distinct miRNAs can predict the response to two different radiochemotherapy regimens. Development of novel miRNA therapeutics has a high clinical potential for further improving treatment of cancerous disease. The use of nanoparticles with distinct surface modifications as miRNA vectors permits prolonged bioavailability, high efficacy in tumor targeting, and low toxicity. Nevertheless, the efficacy of miRNA therapy has only been shown in animal models to date.

  17. Airborne precursor missions in support of SIR-C/X-SAR

    NASA Technical Reports Server (NTRS)

    Evans, D.; Oettl, H.; Pampaloni, P.

    1991-01-01

    The NASA DC-8 and DLR E-SAR airborne imaging radars have been deployed over several sites in Europe and the U.S. in support of SIR-C/X-SAR (Shuttle Imaging Radar-C/X-Synthetic Aperture Radar) science team investigations. To date, data have been acquired in support of studies of alpine glaciers, forests, geology, oceanography, and calibration. An experimental campaign with airborne sensors will take place in Europe in June to July 1991 which will allow multitemporal surveys of several Europeans sites. Current plans are for calibration and ecology experiments to be undertaken in Germany, the Netherlands, Italy, France, and the United Kingdom. Coordinated multitemporal aircraft and ground campaigns are planned in support of hydrology experiments in Italy, the United Kingdom, and Austria. Data will also be acquired in support of oceanogrqhy in the Gulf of Genova, North Atlantic, Straits of Messina and the North Sea. Geology sites will include Campi Flegrei and Vesuvio, Italy.

  18. Delhi, India

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Delhi is the second largest metropolis in India, with a population of 16 million. Located in northern India along the banks of the Yamuna River, Delhi has the status of a federally-administered union territory. Within it is the district of New Delhi, India's capital. Delhi is one of the oldest continually inhabited cites in the world, with traces of human occupation dating to the second millennium BC. The image was acquired September 22, 2003, covers an area of 30.6 x 34.8 km, and is located near 28.6 degrees north latitude, 77.2 degrees east longitude.

    The image was acquired on August 4, 2005, covers an area of 55.8 x 55.8 km, and is located at 68.6 degrees north latitude, 134.7 degrees west longitude.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  19. National Strategy for Countering Biological Threats: Diplomacy and International Programs

    DTIC Science & Technology

    2010-03-18

    for the use of the Committee on Foreign Affairs ( Available via the World Wide Web: http://www.foreignaffairs.house.gov/ VerDate 0ct 09 2002 17:38 Jun...weapons are more likely to be acquired and used by terrorist groups than nuclear weapons. Al- though I might add that it is my belief that bioweapons...acts decisively and with great urgency, it is more likely than not that a weapon of mass destruction would be used in a terrorist at- tack somewhere in

  20. Obtaining Unique, Comprehensive Deep Seismic Sounding Data Sets for CTBT Monitoring and Broad Seismological Studies

    DTIC Science & Technology

    2007-07-02

    TYPE Final Report 3. DATES COVERED (From - To) 26-Sep-01 to 26-Jun-07 4. TITLE AND SUBTITLE OBTAINING UNIQUE, COMPREHENSIVE DEEP SEISMIC ... seismic records from 12 major Deep Seismic Sounding (DSS) projects acquired in 1970-1980’s in the former Soviet Union. The data include 3-component...records from 22 Peaceful Nuclear Explosions (PNEs) and over 500 chemical explosions recorded by a grid of linear, reversed seismic profiles covering a

  1. Feasibility of Radio Frequency Identification (RFID) and Item Unique Identification (IUID) in the Marine Corps Small Arms Weapons Tracking System

    DTIC Science & Technology

    2008-12-01

    The RFID tag can be of various designs, materials , and/or sizes and hold a variable amount of information. Each tag is composed 11 of three...acquiring material from suppliers and in delivering to units in the field (Business Wire, 2005). The military learned an important lesson during...recording of material transfer and enhanced TAV. In the limited implementations of RFID to date, the DoD has seen benefits in inventory management

  2. Current Therapy of Acquired Ocular Toxoplasmosis: A Review.

    PubMed

    Lima, Guilherme Sturzeneker Cerqueira; Saraiva, Patricia Grativol Costa; Saraiva, Fábio Petersen

    2015-11-01

    Caused by the parasite Toxoplasma gondii, ocular toxoplasmosis (OT) is the most common form of posterior infectious uveitis. Combined antiparasitic therapy is the standard treatment for OT, but several other schemes have been proposed. The purpose of the present study was to review the literature on the treatment of OT and provide ophthalmologists with up-to-date information to help reduce OT-related visual morbidity. In conclusion, no ideal treatment scheme was identified; currently prescribed therapeutic schemes yield statistically similar functional outcomes.

  3. Earth Resources Technology Satellite. Cumulative non-US standard catalog, 23 July 1972 - 23 July 1973. Volume 1: Observation ID

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A catalog containing data pertaining to the imagery acquired by the Earth Resources Technology Satellite (ERTS) from its date of launch, July 23, 1972 through the first year of activity is presented. The catalog supersedes the previous catalog which supplied data available through May 1973. Two listings of the imagery are included: (1) an observation identifications listing and (2) a listing of the imagery based on geographical location, the coordinate listing.

  4. Hurricane Season 2005: Katrina

    NASA Technical Reports Server (NTRS)

    2005-01-01

    Seventeen days after Hurricane Katrina flooded New Orleans, much of the city is still under water. In this pair of images from the Advanced Spaceborne Thermal Emission and Reflection Radiometer on NASA's Terra satellite, the affected areas can clearly be seen. The top image mosaic was acquired in April and September 2000, and the bottom image was acquired September 13, 2005. The flooded parts of the city appear dark blue, such as the golf course in the northeast corner, where there is standing water. Areas that have dried out appear light blue gray, such as the city park in the left middle. On the left side of the image, the failed 17th street canal marks a sharp boundary between flooded city to the east, and dry land to the west.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: 10.4 by 7.1 kilometers Location: 30 degrees North latitude, 90.1 degrees West longitude Orientation: North at top Image Data: ASTER bands 1, 2, and 3 Original Data Resolution: 15 meters (49.2 feet) Dates Acquired: September 13, 2005

  5. Experimental Validation of a Closed Brayton Cycle System Transient Simulation

    NASA Technical Reports Server (NTRS)

    Johnson, Paul K.; Hervol, David S.

    2006-01-01

    The Brayton Power Conversion Unit (BPCU) is a closed cycle system with an inert gas working fluid. It is located in Vacuum Facility 6 at NASA Glenn Research Center. Was used in previous solar dynamic technology efforts (SDGTD). Modified to its present configuration by replacing the solar receiver with an electrical resistance heater. The first closed-Brayton-cycle to be coupled with an ion propulsion system. Used to examine mechanical dynamic characteristics and responses. The focus of this work was the validation of a computer model of the BPCU. Model was built using the Closed Cycle System Simulation (CCSS) design and analysis tool. Test conditions were then duplicated in CCSS. Various steady-state points. Transients involving changes in shaft rotational speed and heat input. Testing to date has shown that the BPCU is able to generate meaningful, repeatable data that can be used for computer model validation. Results generated by CCSS demonstrated that the model sufficiently reproduced the thermal transients exhibited by the BPCU system. CCSS was also used to match BPCU steady-state operating points. Cycle temperatures were within 4.1% of the data (most were within 1%). Cycle pressures were all within 3.2%. Error in alternator power (as much as 13.5%) was attributed to uncertainties in the compressor and turbine maps and alternator and bearing loss models. The acquired understanding of the BPCU behavior gives useful insight for improvements to be made to the CCSS model as well as ideas for future testing and possible system modifications.

  6. Hydrodynamics of an electrochemical membrane bioreactor.

    PubMed

    Wang, Ya-Zhou; Wang, Yun-Kun; He, Chuan-Shu; Yang, Hou-Yun; Sheng, Guo-Ping; Shen, Jin-You; Mu, Yang; Yu, Han-Qing

    2015-05-22

    An electrochemical membrane bioreactor (EMBR) has recently been developed for energy recovery and wastewater treatment. The hydrodynamics of the EMBR would significantly affect the mass transfers and reaction kinetics, exerting a pronounced effect on reactor performance. However, only scarce information is available to date. In this study, the hydrodynamic characteristics of the EMBR were investigated through various approaches. Tracer tests were adopted to generate residence time distribution curves at various hydraulic residence times, and three hydraulic models were developed to simulate the results of tracer studies. In addition, the detailed flow patterns of the EMBR were acquired from a computational fluid dynamics (CFD) simulation. Compared to the tank-in-series and axial dispersion ones, the Martin model could describe hydraulic performance of the EBMR better. CFD simulation results clearly indicated the existence of a preferential or circuitous flow in the EMBR. Moreover, the possible locations of dead zones in the EMBR were visualized through the CFD simulation. Based on these results, the relationship between the reactor performance and the hydrodynamics of EMBR was further elucidated relative to the current generation. The results of this study would benefit the design, operation and optimization of the EMBR for simultaneous energy recovery and wastewater treatment.

  7. Hydrodynamics of an Electrochemical Membrane Bioreactor

    PubMed Central

    Wang, Ya-Zhou; Wang, Yun-Kun; He, Chuan-Shu; Yang, Hou-Yun; Sheng, Guo-Ping; Shen, Jin-You; Mu, Yang; Yu, Han-Qing

    2015-01-01

    An electrochemical membrane bioreactor (EMBR) has recently been developed for energy recovery and wastewater treatment. The hydrodynamics of the EMBR would significantly affect the mass transfers and reaction kinetics, exerting a pronounced effect on reactor performance. However, only scarce information is available to date. In this study, the hydrodynamic characteristics of the EMBR were investigated through various approaches. Tracer tests were adopted to generate residence time distribution curves at various hydraulic residence times, and three hydraulic models were developed to simulate the results of tracer studies. In addition, the detailed flow patterns of the EMBR were acquired from a computational fluid dynamics (CFD) simulation. Compared to the tank-in-series and axial dispersion ones, the Martin model could describe hydraulic performance of the EBMR better. CFD simulation results clearly indicated the existence of a preferential or circuitous flow in the EMBR. Moreover, the possible locations of dead zones in the EMBR were visualized through the CFD simulation. Based on these results, the relationship between the reactor performance and the hydrodynamics of EMBR was further elucidated relative to the current generation. The results of this study would benefit the design, operation and optimization of the EMBR for simultaneous energy recovery and wastewater treatment. PMID:25997399

  8. Use of Airborne Hyperspectral Data in the Simulation of Satellite Images

    NASA Astrophysics Data System (ADS)

    de Miguel, Eduardo; Jimenez, Marcos; Ruiz, Elena; Salido, Elena; Gutierrez de la Camara, Oscar

    2016-08-01

    The simulation of future images is part of the development phase of most Earth Observation missions. This simulation uses frequently as starting point images acquired from airborne instruments. These instruments provide the required flexibility in acquisition parameters (time, date, illumination and observation geometry...) and high spectral and spatial resolution, well above the target values (as required by simulation tools). However, there are a number of important problems hampering the use of airborne imagery. One of these problems is that observation zenith angles (OZA), are far from those that the misisons to be simulated would use.We examine this problem by evaluating the difference in ground reflectance estimated from airborne images for different observation/illumination geometries. Next, we analyze a solution for simulation purposes, in which a Bi- directional Reflectance Distribution Function (BRDF) model is attached to an image of the isotropic surface reflectance. The results obtained confirm the need for reflectance anisotropy correction when using airborne images for creating a reflectance map for simulation purposes. But this correction should not be used without providing the corresponding estimation of BRDF, in the form of model parameters, to the simulation teams.

  9. Research Data Acquired in World-Class, 60-atm Subsonic Combustion Rig

    NASA Technical Reports Server (NTRS)

    Lee, Chi-Ming; Wey, Changlie

    1999-01-01

    NASA Lewis Research Center's new, world-class, 60-atmosphere (atm) combustor research facility, the Advanced Subsonic Combustion Rig (ASCR), is in operation and producing highly unique research data. Specifically, data were acquired at high pressures and temperatures representative of future subsonic engines from a fundamental flametube configuration with an advanced fuel injector. The data acquired include exhaust emissions as well as pressure and temperature distributions. Results to date represent an improved understanding of nitrous oxide (NOx) formation at high pressures and temperatures and include an NOx emissions reduction greater than 70 percent with an advanced fuel injector at operating pressures to 800 pounds per square inch absolute (psia). ASCR research is an integral part of the Advanced Subsonic Technology (AST) Propulsion Program. This program is developing critical low-emission combustion technology that will result in the next generation of gas turbine engines producing 50 to 70 percent less NOx emissions in comparison to 1996 International Civil Aviation Organization (ICAO) limits. The results to date indicate that the AST low-emission combustor goals of reducing NOx emissions by 50 to 70 percent are feasible. U.S. gas turbine manufacturers have started testing the low-emissions combustors at the ASCR. This collaborative testing will enable the industry to develop low-emission combustors at the high pressure and temperature conditions of future subsonic engines. The first stage of the flametube testing has been implemented. Four GE Aircraft Engines low-emissions fuel injector concepts, three Pratt & Whitney concepts, and two Allison concepts have been tested at Lewis ASCR facility. Subsequently, the flametube was removed from the test stand, and the sector combustor was installed. The testing of low emissions sector has begun. Low-emission combustors developed as a result of ASCR research will enable U.S. engine manufacturers to compete on a worldwide basis by producing environmentally acceptable commercial engines.

  10. Cognitive skills training in digital era: A paradigm shift in surgical education using the TaTME model.

    PubMed

    Knol, Joep; Keller, Deborah S

    2018-04-30

    Surgical competence is a complex, multifactorial process, requiring ample time and training. Optimal training is based on acquiring knowledge and psychomotor and cognitive skills. Practicing surgical skills is one of the most crucial tasks for both the novice surgeon learning new procedures and surgeons already in practice learning new techniques. Focus is placed on teaching traditional technical skills, but the importance of cognitive skills cannot be underestimated. Cognitive skills allow recognizing environmental cues to improve technical performance including situational awareness, mental readiness, risk assessment, anticipating problems, decision-making, adaptation, and flexibility, and may also accelerate the trainee's understanding of a procedure, formalize the steps being practiced, and reduce the overall training time to become technically proficient. The introduction and implementation of the transanal total mesorectal excision (TaTME) into practice may be the best demonstration of this new model of teaching and training, including pre-training, course attendance, and post-course guidance on technical and cognitive skills. To date, the TaTME framework has been the ideal model for structured training to ensure safe implementation. Further development of metrics to grade successful learning and assessment of long term outcomes with the new pathway will confirm the success of this training model. Copyright © 2018 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. All rights reserved.

  11. Acquired resistance mechanisms to tyrosine kinase inhibitors in lung cancer with activating epidermal growth factor receptor mutation--diversity, ductility, and destiny.

    PubMed

    Suda, Kenichi; Mizuuchi, Hiroshi; Maehara, Yoshihiko; Mitsudomi, Tetsuya

    2012-12-01

    Lung cancers that harbor somatic activating mutations in the gene for the epidermal growth factor receptor (EGFR) depend on mutant EGFR for their proliferation and survival; therefore, lung cancer patients with EGFR mutations often dramatically respond to orally available EGFR tyrosine kinase inhibitors (TKIs). However, emergence of acquired resistance is virtually inevitable, thus limiting improvement in patient outcomes. To elucidate and overcome this acquired resistance, multidisciplinary basic and clinical investigational approaches have been applied, using in vitro cell line models or samples obtained from lung cancer patients treated with EGFR-TKIs. These efforts have revealed several acquired resistance mechanisms and candidates, including EGFR secondary mutations (T790M and other rare mutations), MET amplification, PTEN downregulation, CRKL amplification, high-level HGF expression, FAS-NFκB pathway activation, epithelial-mesenchymal transition, and conversion to small cell lung cancer. Interestingly, cancer cells harbor potential destiny and ductility together in acquiring resistance to EGFR-TKIs, as shown in in vitro acquired resistance models. Molecular mechanisms of "reversible EGFR-TKI tolerance" that occur in early phase EGFR-TKI exposure have been identified in cell line models. Furthermore, others have reported molecular markers that can predict response to EGFR-TKIs in clinical settings. Deeper understanding of acquired resistance mechanisms to EGFR-TKIs, followed by the development of molecular target drugs that can overcome the resistance, might turn this fatal disease into a chronic disorder.

  12. Exposure to family violence and attachment styles as predictors of dating violence perpetration among men and women: a mediational model.

    PubMed

    Lee, Mary; Reese-Weber, Marla; Kahn, Jeffrey H

    2014-01-01

    This study examined a multiple mediator model explaining how sibling perpetration and one's attachment style mediate the relation between parent-to-child victimization and dating violence perpetration. A sample of undergraduate students (n = 392 women, n = 89 men) completed measures of the aforementioned variables on an Internet survey. For men, path analyses found no mediation; parent-to-child victimization had a direct association with dating violence perpetration, no association was found between sibling perpetration and dating violence perpetration, and attachment anxiety, but not attachment avoidance, was positively associated with dating violence perpetration for men. For women, the hypothesized mediation model was supported; parent-to-child victimization had a direct association with dating violence perpetration, and sibling perpetration and attachment anxiety served as mediating variables. Attachment avoidance was not associated with dating violence perpetration for women. Implications for future research and clinical practice are discussed.

  13. Multiscale sagebrush rangeland habitat modeling in southwest Wyoming

    USGS Publications Warehouse

    Homer, Collin G.; Aldridge, Cameron L.; Meyer, Debra K.; Coan, Michael J.; Bowen, Zachary H.

    2009-01-01

    Sagebrush-steppe ecosystems in North America have experienced dramatic elimination and degradation since European settlement. As a result, sagebrush-steppe dependent species have experienced drastic range contractions and population declines. Coordinated ecosystem-wide research, integrated with monitoring and management activities, would improve the ability to maintain existing sagebrush habitats. However, current data only identify resource availability locally, with rigorous spatial tools and models that accurately model and map sagebrush habitats over large areas still unavailable. Here we report on an effort to produce a rigorous large-area sagebrush-habitat classification and inventory with statistically validated products and estimates of precision in the State of Wyoming. This research employs a combination of significant new tools, including (1) modeling sagebrush rangeland as a series of independent continuous field components that can be combined and customized by any user at multiple spatial scales; (2) collecting ground-measured plot data on 2.4-meter imagery in the same season the satellite imagery is acquired; (3) effective modeling of ground-measured data on 2.4-meter imagery to maximize subsequent extrapolation; (4) acquiring multiple seasons (spring, summer, and fall) of an additional two spatial scales of imagery (30 meter and 56 meter) for optimal large-area modeling; (5) using regression tree classification technology that optimizes data mining of multiple image dates, ratios, and bands with ancillary data to extrapolate ground training data to coarser resolution sensors; and (6) employing rigorous accuracy assessment of model predictions to enable users to understand the inherent uncertainties. First-phase results modeled eight rangeland components (four primary targets and four secondary targets) as continuous field predictions. The primary targets included percent bare ground, percent herbaceousness, percent shrub, and percent litter. The four secondary targets included percent sagebrush (Artemisia spp.), percent big sagebrush (Artemisia tridentata), percent Wyoming sagebrush (Artemisia tridentata wyomingensis), and sagebrush height (centimeters). Results were validated by an independent accuracy assessment with root mean square error (RMSE) values ranging from 6.38 percent for bare ground to 2.99 percent for sagebrush at the QuickBird scale and RMSE values ranging from 12.07 percent for bare ground to 6.34 percent for sagebrush at the full Landsat scale. Subsequent project phases are now in progress, with plans to deliver products that improve accuracies of existing components, model new components, complete models over larger areas, track changes over time (from 1988 to 2007), and ultimately model wildlife population trends against these changes. We believe these results offer significant improvement in sagebrush rangeland quantification at multiple scales and offer users products that have been rigorously validated.

  14. 3D Gravimetric Modeling of the Spreading System North and Southeast of the Rodriguez Triple Junction (Indian Ocean)

    NASA Astrophysics Data System (ADS)

    Heyde, I.; Girolami, C.; Barckhausen, U.; Freitag, R.

    2017-12-01

    Hydrothermal vent fields along mid-ocean ridges can be metal-rich and thus of great importance for the industries in the future. By order of the German Federal Ministry of Economics and in coordination with the International Seabed Authority (ISA), BGR explores potential areas of the active spreading system in the Indian Ocean. A main goal is the identification of inactive seafloor massive sulfides (SMS) with the aid of modern exploration techniques. Important contributions could be expected from bathymetric, magnetic, and gravity datasets, which can be acquired simultaneously time from the sea surface within relatively short ship time. The area of interest is located between 21°S and 28°S and includes the southern Central Indian Ridge (CIR) and the northern Southeast Indian Ridge (SEIR). In this study we analyzed the marine gravity and bathymetric data acquired during six research cruises. The profiles running perpendicular to the ridge axis have a mean length of 60 km. Magnetic studies reveal that the parts of the ridges covered are geologically very young with the oldest crust dating back to about 1 Ma. To extend the area outside the ridges, the shipboard data were complemented with data derived from satellite radar altimeter measurements. We analyzed the gravity anomalies along sections which cross particular geologic features (uplifted areas, accommodation zones, hydrothermal fields, and areas with hints for extensional processes e.g. oceanic core complexes) to establish a correlation between the gravity anomalies and the surface geology. Subsequently, for both ridge segments 3D density models were developed. We started with simple horizontally layered models, which, however, do not explain the measured anomalies satisfyingly. The density values of the crust and the upper mantle in the ridge areas had to be reduced. Finally, the models show the lateral heterogeneity and the variations in the thickness of the oceanic crust. There are areas characterized by crustal thickening related to magmatic accretion and areas of crustal thinning related to depleted accretion and exposure of OCCs.

  15. Using vertebrate prey capture locations to identify cover type selection patterns of nocturnally foraging Burrowing Owls.

    PubMed

    Marsh, Alan; Bayne, Erin M; Wellicome, Troy I

    2014-07-01

    Studies of habitat selection often measure an animal's use of space via radiotelemetry or GPS-based technologies. Such data tend to be analyzed using a resource selection function, despite the fact that the actual resources acquired are typically not recorded. Without explicit proof of resource use, conclusions from RSF models are based on assumptions regarding an animal's behavior and the resources gained. Conservation initiatives are often based on space-use models, and could be detrimental to the target species if these assumptions are incorrect. We used GPS dataloggers and digital video recorders to determine precise locations where nocturnally foraging Burrowing Owls acquired food resources (vertebrate prey). We compared land cover type selection patterns using a presence-only resource selection function (RSF) to a model that incorporated prey capture locations (CRSF). We also compared net prey returns in each cover type to better measure reward relative to foraging effort. The RSF method did not reflect prey capture patterns and cover-type rankings from this model were quite different from models that used only locations where prey was known to have been obtained. Burrowing Owls successfully foraged across all cover types; however, return vs. effort models indicate that different cover types were of higher quality than those identified using resource selection functions. Conclusions about the type of resources acquired should not be made from RSF-style models without evidence that the actual resource of interest was acquired. Conservation efforts based on RSF models alone may be ineffective or detrimental to the target species if the limiting resource and where it is acquired are not properly identified.

  16. Inverted Apatite (U-Th)/He and Fission-track Dates from the Rae craton, Baffin Island, Canada and Implications for Apatite Radiation Damage-He Diffusivity Models

    NASA Astrophysics Data System (ADS)

    Ault, A. K.; Reiners, P. W.; Thomson, S. N.; Miller, G. H.

    2015-12-01

    Coupled apatite (U-Th)/He and fission-track (AFT) thermochronology data from the same sample can be used to decipher complex low temperature thermal histories and evaluate compatibility between these two methods. Existing apatite He damage-diffusivity models parameterize radiation damage annealing as fission-track annealing and yield inverted apatite He and AFT dates for samples with prolonged residence in the He partial retention zone. Apatite chemistry also impacts radiation damage and fission-track annealing, temperature sensitivity, and dates in both systems. We present inverted apatite He and AFT dates from the Rae craton, Baffin Island, Canada, that cannot be explained by apatite chemistry or existing damage-diffusivity and fission track models. Apatite He dates from 34 individual analyses from 6 samples range from 237 ± 44 Ma to 511 ± 25 Ma and collectively define a positive date-eU relationship. AFT dates from these same samples are 238 ± 15 Ma to 350 ± 20 Ma. These dates and associated track length data are inversely correlated and define the left segment of a boomerang diagram. Three of the six samples with 20-90 ppm eU apatite grains yield apatite He and AFT dates inverted by 300 million years. These samples have average apatite Cl chemistry of ≤0.02 wt.%, with no correlation between Cl content and Dpar. Thermal history simulations using geologic constraints, an apatite He radiation damage accumulation and annealing model, apatite He dates with the range of eU values, and AFT date and track length data, do not yield any viable time-temperature paths. Apatite He and AFT data modeled separately predict thermal histories with Paleozoic-Mesozoic peaks reheating temperatures differing by ≥15 °C. By modifying the parameter controlling damage annealing (Rmr0) from the canonical 0.83 to 0.5-0.6, forward models reproduce the apatite He date-eU correlation and AFT dates with a common thermal history. Results imply apatite radiation damage anneals at higher temperatures than fission-track damage and the impact on coupled apatite He and AFT dates is magnified for protracted cooling histories. Further experimental and field-based tests are important for refining radiation damage and fission-track annealing parameters for accurate interpretation of apatite He- and AFT-derived thermal histories.

  17. Development of a Model to Predict the Primary Infection Date of Bacterial Spot (Xanthomonas campestris pv. vesicatoria) on Hot Pepper.

    PubMed

    Kim, Ji-Hoon; Kang, Wee-Soo; Yun, Sung-Chul

    2014-06-01

    A population model of bacterial spot caused by Xanthomonas campestris pv. vesicatoria on hot pepper was developed to predict the primary disease infection date. The model estimated the pathogen population on the surface and within the leaf of the host based on the wetness period and temperature. For successful infection, at least 5,000 cells/ml of the bacterial population were required. Also, wind and rain were necessary according to regression analyses of the monitored data. Bacterial spot on the model is initiated when the pathogen population exceeds 10(15) cells/g within the leaf. The developed model was validated using 94 assessed samples from 2000 to 2007 obtained from monitored fields. Based on the validation study, the predicted initial infection dates varied based on the year rather than the location. Differences in initial infection dates between the model predictions and the monitored data in the field were minimal. For example, predicted infection dates for 7 locations were within the same month as the actual infection dates, 11 locations were within 1 month of the actual infection, and only 3 locations were more than 2 months apart from the actual infection. The predicted infection dates were mapped from 2009 to 2012; 2011 was the most severe year. Although the model was not sensitive enough to predict disease severity of less than 0.1% in the field, our model predicted bacterial spot severity of 1% or more. Therefore, this model can be applied in the field to determine when bacterial spot control is required.

  18. Development of a Model to Predict the Primary Infection Date of Bacterial Spot (Xanthomonas campestris pv. vesicatoria) on Hot Pepper

    PubMed Central

    Kim, Ji-Hoon; Kang, Wee-Soo; Yun, Sung-Chul

    2014-01-01

    A population model of bacterial spot caused by Xanthomonas campestris pv. vesicatoria on hot pepper was developed to predict the primary disease infection date. The model estimated the pathogen population on the surface and within the leaf of the host based on the wetness period and temperature. For successful infection, at least 5,000 cells/ml of the bacterial population were required. Also, wind and rain were necessary according to regression analyses of the monitored data. Bacterial spot on the model is initiated when the pathogen population exceeds 1015 cells/g within the leaf. The developed model was validated using 94 assessed samples from 2000 to 2007 obtained from monitored fields. Based on the validation study, the predicted initial infection dates varied based on the year rather than the location. Differences in initial infection dates between the model predictions and the monitored data in the field were minimal. For example, predicted infection dates for 7 locations were within the same month as the actual infection dates, 11 locations were within 1 month of the actual infection, and only 3 locations were more than 2 months apart from the actual infection. The predicted infection dates were mapped from 2009 to 2012; 2011 was the most severe year. Although the model was not sensitive enough to predict disease severity of less than 0.1% in the field, our model predicted bacterial spot severity of 1% or more. Therefore, this model can be applied in the field to determine when bacterial spot control is required. PMID:25288995

  19. Predictors of emotional and physical dating violence in a sample of serious juvenile offenders.

    PubMed

    Sweeten, Gary; Larson, Matthew; Piquero, Alex R

    2016-10-01

    We estimate group-based dating violence trajectories and identify the adolescent risk factors that explain membership in each trajectory group. Using longitudinal data from the Pathways to Desistance Study, which follows a sample of 1354 serious juvenile offenders from Philadelphia, Pennsylvania and Phoenix, Arizona between mid-adolescence and early adulthood, we estimate group-based trajectory models of both emotional dating violence and physical dating violence over a span of five years in young adulthood. We then estimate multinomial logistic regression models to identify theoretically motivated risk factors that predict membership in these groups. We identified three developmental patterns of emotional dating violence: none (33%), low-level (59%) and high-level decreasing (8%). The best-fitting model for physical dating violence also had three groups: none (73%), low-level (24%) and high-level (3%). Race/ethnicity, family and psychosocial variables were among the strongest predictors of both emotional and physical dating violence. In addition, delinquency history variables predicted emotional dating violence and relationship variables predicted physical dating violence. Dating violence is quite prevalent in young adulthood among serious juvenile offenders. Numerous predictors distinguish between chronic dating violence perpetrators and other groups. These may suggest points of intervention for reducing future violence. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  20. Can phenological models predict tree phenology accurately under climate change conditions?

    NASA Astrophysics Data System (ADS)

    Chuine, Isabelle; Bonhomme, Marc; Legave, Jean Michel; García de Cortázar-Atauri, Inaki; Charrier, Guillaume; Lacointe, André; Améglio, Thierry

    2014-05-01

    The onset of the growing season of trees has been globally earlier by 2.3 days/decade during the last 50 years because of global warming and this trend is predicted to continue according to climate forecast. The effect of temperature on plant phenology is however not linear because temperature has a dual effect on bud development. On one hand, low temperatures are necessary to break bud dormancy, and on the other hand higher temperatures are necessary to promote bud cells growth afterwards. Increasing phenological changes in temperate woody species have strong impacts on forest trees distribution and productivity, as well as crops cultivation areas. Accurate predictions of trees phenology are therefore a prerequisite to understand and foresee the impacts of climate change on forests and agrosystems. Different process-based models have been developed in the last two decades to predict the date of budburst or flowering of woody species. They are two main families: (1) one-phase models which consider only the ecodormancy phase and make the assumption that endodormancy is always broken before adequate climatic conditions for cell growth occur; and (2) two-phase models which consider both the endodormancy and ecodormancy phases and predict a date of dormancy break which varies from year to year. So far, one-phase models have been able to predict accurately tree bud break and flowering under historical climate. However, because they do not consider what happens prior to ecodormancy, and especially the possible negative effect of winter temperature warming on dormancy break, it seems unlikely that they can provide accurate predictions in future climate conditions. It is indeed well known that a lack of low temperature results in abnormal pattern of bud break and development in temperate fruit trees. An accurate modelling of the dormancy break date has thus become a major issue in phenology modelling. Two-phases phenological models predict that global warming should delay or compromise dormancy break at the species equatorward range limits leading to a delay or even impossibility to flower or set new leaves. These models are classically parameterized with flowering or budburst dates only, with no information on the dormancy break date because this information is very scarce. We evaluated the efficiency of a set of process-based phenological models to accurately predict the dormancy break dates of four fruit trees. Our results show that models calibrated solely with flowering or budburst dates do not accurately predict the dormancy break date. Providing dormancy break date for the model parameterization results in much more accurate simulation of this latter, with however a higher error than that on flowering or bud break dates. But most importantly, we show also that models not calibrated with dormancy break dates can generate significant differences in forecasted flowering or bud break dates when using climate scenarios. Our results claim for the urgent need of massive measurements of dormancy break dates in forest and fruit trees to yield more robust projections of phenological changes in a near future.

  1. Microwave soil moisture measurements and analysis

    NASA Technical Reports Server (NTRS)

    Newton, R. W.; Howell, T. A.; Nieber, J. L.; Vanbavel, C. H. M. (Principal Investigator)

    1980-01-01

    An effort to develop a model that simulates the distribution of water content and of temperature in bare soil is documented. The field experimental set up designed to acquire the data to test this model is described. The microwave signature acquisition system (MSAS) field measurements acquired in Colby, Kansas during the summer of 1978 are pesented.

  2. Identification of brome grass infestations in southwest Oklahoma using multi-temporal Landsat imagery

    NASA Astrophysics Data System (ADS)

    Yan, D.; de Beurs, K.

    2013-12-01

    The extensive infestation of brome grasses (Cheatgrass, Rye brome and Japanese brome) in southwest Oklahoma imposes negative impacts on local economy and ecosystem in terms of decreasing crop and forage production and increasing fire risk. Previously proposed methodologies on brome grass detection are found ill-suitable for southwest Oklahoma as a result of similar responses of background vegetation to inter-annual variability of rainfall. In this study, we aim to identify brome grass infestations by detecting senescent brome grasses using the 2011 Cultivated Land Cover Data Sets and the difference Normalized Difference Infrared Index (NDII) derived from multi-temporal Landsat imagery. Landsat imageries acquired on May 18th and June 10th 2013 by Operational Land Imager and Enhanced Thematic Mapper plus were used. The imagery acquisition dates correspond to the peak growth and senescent time of brome grasses, respectively. The difference NDII was calculated by subtracting the NDII image acquired in May from the June NDII image. Our hypotheses is that senescent brome grasses and crop/pasture fields harvested between the two image acquisition dates can be distinguished from background land cover classes because of their increases in NDII due to decreased water absorption by senescent vegetation in the shortwave infrared region. The Cultivated Land Cover Data Sets were used to further separate senescent brome grass patches from newly harvested crop/pasture fields. Ground truth data collected during field trips in June, July and August of 2013 were used to validate the detection results.

  3. Augustine Volcano, Cook Inlet, Alaska (January 12, 2006)

    NASA Technical Reports Server (NTRS)

    2006-01-01

    Since last spring, the U.S. Geological Survey's Alaska Volcano Observatory (AVO) has detected increasing volcanic unrest at Augustine Volcano in Cook Inlet, Alaska near Anchorage. Based on all available monitoring data, AVO regards that an eruption similar to 1976 and 1986 is the most probable outcome. During January, activity has been episodic, and characterized by emission of steam and ash plumes, rising to altitudes in excess of 9,000 m (30,000 ft), and posing hazards to aircraft in the vicinity. An ASTER image was acquired at 12:42 AST on January 12, 2006, during an eruptive phase of Augustine. The perspective rendition shows the eruption plume derived from the ASTER image data. ASTER's stereo viewing capability was used to calculate the 3-dimensional topography of the eruption cloud as it was blown to the south by prevailing winds. From a maximum height of 3060 m (9950 ft), the plume cooled and its top descended to 1900 m (6175 ft). The perspective view shows the ASTER data draped over the plume top topography, combined with a base image acquired in 2000 by the Landsat satellite, that is itself draped over ground elevation data from the Shuttle Radar Topography Mission. The topographic relief has been increased 1.5 times for this illustration. Comparison of the ASTER plume topography data with ash dispersal models and weather radar data will allow the National Weather Service to validate and improve such models. These models are used to forecast volcanic ash plume trajectories and provide hazard alerts and warnings to aircraft in the Alaska region.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

    Size: Roughly 25 km (15 miles) across; scale varies in this perspective view Location: 59.3 deg. North latitude, 153.4 deg. West longitude Orientation: View from southwest towards the northeast Vertical Exaggeration: 2 Eruption plume and Elevation: 30 m ASTER, (1-arcsecond) Image Data: Landsat bands 7, 4 and 2 Ground Topography Data: SRTM 90 m data, acquired January 2000 Date Acquired: ASTER: January 12, 2006; Landsat: September 17, 2000

  4. Source models for the March 5-9, 2011 Kamoamoa fissure eruption, Kilauea Volcano, Hawai`i, constrained by InSAR and in-situ observations

    NASA Astrophysics Data System (ADS)

    Lundgren, P.; Poland, M. P.; Miklius, A.; Yun, S.; Fielding, E. J.; Liu, Z.; Tanaka, A.; Szeliga, W. M.; Hensley, S.

    2011-12-01

    On March 5, 2011, the Kamoamoa fissure eruption began along the east rift zone (ERZ) of Kilauea Volcano. It followed several months of pronounced inflation at Kilauea's summit and was the first dike intrusion into the ERZ since June 2007. The eruption began in the late afternoon of March 5, 2011 (Hawaii Standard Time; UTC-10:00 hrs) with rapid deflation beginning at Pu'u 'O'o crater along the ERZ and followed about 30 minutes later at the summit. Magma from both locations fed the intrusion and an eruption that included lava fountaining along a set of discontinuous eruptive fissures ~2 km in length located between Napau and Pu'u 'O'o craters. Eruptive activity jumped between fissure segments until it ended on the night of March 9. A rich InSAR data set exists for this eruption from the COSMO-SkyMed (CSK), TerraSAR-X (TSX), ALOS PALSAR, and UAVSAR sensors. CSK data acquired on March 7 and processed that same day provided the earliest, quasi-real-time SAR data for this event. By March 10, after the eruption had ended, we had three CSK acquisitions and one ALOS scene acquired and processed. At present we have the following satellite data (UTC dates): ALOS March 6, 9, 11; CSK March 7, 10, 11; TSX March 11; from a mixture of ascending and descending tracks. UAVSAR airborne SAR data were acquired in early May 2011. Preliminary UAVSAR results are encouraging and complete processing should provide high-resolution data from four viewing directions. SAR data were acquired on all days of the eruption but March 8, allowing us to examine the progression of the dike opening beneath the surface with excellent spatial and temporal resolution. We use a combination of unwrapped interferograms, azimuthal pixel offsets, and in-situ data from GPS and electronic tiltmeters to model dike opening and summit deflation. GPS data are from the Hawaiian Volcano Observatory (HVO) continuous GPS network augmented by campaign occupations closer to the eruption area. Continuous tilt measurements are concentrated near Kilauea's summit and Pu'u 'O'o crater, with one site in between to help constrain dike propagation. To model the sources we use a Markov Chain Monte Carlo (MCMC) optimization to solve for Kilauea caldera source(s) and for the Kamoamoa dike dip, where we fixed the surface location of the dike based on field observations and solved for the opening distribution using Laplacian smoothing for a multi-patch dike. Preliminary models of the dike show 1-2 meters of dike opening at the beginning of the eruption, reaching 2-3 meters of opening by the end of the eruption. Preliminary results for the caldera favor a shallow source centered at roughly 1.5 km depth and extending in a SW-NE direction. Initial estimates of the volume changes show less than a 2 MCM (million cubic meters) decrease at the summit compared to a roughly 10 MCM increase for the dike. This difference suggests that much of the magma came from sources other than the shallow Kilauea summit source.

  5. Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2).

    PubMed

    Knoebl, P; Marco, P; Baudo, F; Collins, P; Huth-Kühne, A; Nemes, L; Pellegrini, F; Tengborn, L; Lévesque, H

    2012-04-01

    Acquired hemophilia A (AHA) is a rare autoimmune disease caused by autoantibodies against coagulation factor VIII and characterized by spontaneous hemorrhage in patients with no previous family or personal history of bleeding. Although data on several AHA cohorts have been collected, limited information is available on the optimal management of AHA. The European Acquired Hemophilia Registry (EACH2) was established to generate a prospective, large-scale, pan-European database on demographics, diagnosis, underlying disorders, bleeding characteristics, treatment and outcome of AHA patients. Five hundred and one (266 male, 235 female) patients from 117 centers and 13 European countries were included in the registry between 2003 and 2008. In 467 cases, hemostasis investigations and AHA diagnosis were triggered by a bleeding event. At diagnosis, patients were a median of 73.9 years. AHA was idiopathic in 51.9%; malignancy or autoimmune diseases were associated with 11.8% and 11.6% of cases. Fifty-seven per cent of the non-pregnancy-related cases were male. Four hundred and seventy-four bleeding episodes were reported at presentation, and hemostatic therapy initiated in 70.5% of patients. Delayed diagnosis significantly impacted treatment initiation in 33.5%. Four hundred and seventy-seven patients underwent immunosuppression, and 72.6% achieved complete remission. Representing the largest collection of consecutive AHA cases to date, EACH2 facilitates the analysis of a variety of open questions in AHA. © 2012 International Society on Thrombosis and Haemostasis.

  6. Soybean canopy reflectance as influenced by cultural practices. [West Lafayette, Indiana

    NASA Technical Reports Server (NTRS)

    Bauer, M. E. (Principal Investigator); Kollenkark, J. C.; Daughtry, C. S. T.

    1981-01-01

    Experiments were conducted at West Lafayette, Indiana in 1978 and 1979 to study the reflectance factor of soybean canopies as affected by differences in row width, population, planting date, cultivar and soil type. Reflectance factor data were acquired throughout the growing season with a LANDSAT-band radiometer. Agronomic data included plant height, leaf area index, development stage, total fresh and dry biomass, percent soil cover, and grain yield. The results indicate that row width, planting date, and cultivar influence the percent soil cover, leaf area index, and biomass present, which are in turn related to the multispectral reflectance. Additionally, the reflectance data were quite sensitive to the onset of senescence. Soil color and moisture were found to be important factors influencing the reflectance in single LANDSAT bands, but the near infrared/red reflectance ratio and the greeness transformation were less sensitive than the single bands to the soil background present.

  7. Teaching resources for dermatology on the WWW--quiz system and dynamic lecture scripts using a HTTP-database demon.

    PubMed Central

    Bittorf, A.; Diepgen, T. L.

    1996-01-01

    The World Wide Web (WWW) is becoming the major way of acquiring information in all scientific disciplines as well as in business. It is very well suitable for fast distribution and exchange of up to date teaching resources. However, to date most teaching applications on the Web do not use its full power by integrating interactive components. We have set up a computer based training (CBT) framework for Dermatology, which consists of dynamic lecture scripts, case reports, an atlas and a quiz system. All these components heavily rely on an underlying image database that permits the creation of dynamic documents. We used a demon process that keeps the database open and can be accessed using HTTP to achieve better performance and avoid the overhead involved by starting CGI-processes. The result of our evaluation was very encouraging. Images Figure 3 PMID:8947625

  8. The 2008 Passage of Jupiter's Great Red Spot and Oval BA as Observed from Hubble/WFPC2

    NASA Technical Reports Server (NTRS)

    Simon-Miller, Amy A.; Chanover, N. J.; Orton, G. S.; Tsavaris, I.

    2008-01-01

    Hubble Space Telescope data of the passage of Jupiter's Great Red Spot (GRS) and Oval BA were acquired on May 15, June 28 (near closest approach), and July 8. Wind fields were measured from Wide Field Planetary Camera 2 (WFPC2) data with 10-hour separations before and after closest approach, and within the GRS with 40-minute separations on all three dates. Color information was also derived using 8 narrowband WFPC2 filters from 343 to 673-nm on all three dates. We will present the results of principal components and wind analyses and discuss unique features seen in this data set. In addition, we will highlight any changes observed in the GRS, Oval BA and their surroundings as a result of the passage, including the movement of a smaller red anticyclone from west of the GRS, around its southern periphery, and to the east of the GRS.

  9. Predictions of heading date in bread wheat (Triticum aestivum L.) using QTL-based parameters of an ecophysiological model

    PubMed Central

    Bogard, Matthieu; Ravel, Catherine; Paux, Etienne; Bordes, Jacques; Balfourier, François; Chapman, Scott C.; Le Gouis, Jacques; Allard, Vincent

    2014-01-01

    Prediction of wheat phenology facilitates the selection of cultivars with specific adaptations to a particular environment. However, while QTL analysis for heading date can identify major genes controlling phenology, the results are limited to the environments and genotypes tested. Moreover, while ecophysiological models allow accurate predictions in new environments, they may require substantial phenotypic data to parameterize each genotype. Also, the model parameters are rarely related to all underlying genes, and all the possible allelic combinations that could be obtained by breeding cannot be tested with models. In this study, a QTL-based model is proposed to predict heading date in bread wheat (Triticum aestivum L.). Two parameters of an ecophysiological model (V sat and P base, representing genotype vernalization requirements and photoperiod sensitivity, respectively) were optimized for 210 genotypes grown in 10 contrasting location × sowing date combinations. Multiple linear regression models predicting V sat and P base with 11 and 12 associated genetic markers accounted for 71 and 68% of the variance of these parameters, respectively. QTL-based V sat and P base estimates were able to predict heading date of an independent validation data set (88 genotypes in six location × sowing date combinations) with a root mean square error of prediction of 5 to 8.6 days, explaining 48 to 63% of the variation for heading date. The QTL-based model proposed in this study may be used for agronomic purposes and to assist breeders in suggesting locally adapted ideotypes for wheat phenology. PMID:25148833

  10. New Directions for Preventing Dating Violence in Adolescence: The Study of Gender Models

    PubMed Central

    Santoro, Chiara; Martínez-Ferrer, Belén; Monreal Gimeno, Carmen; Musitu, Gonzalo

    2018-01-01

    Dating violence is a huge transcultural and alarming phenomenon, directly linked with endless discrimination against women. The latest research on dating violence in adolescence shows how dating violence is persistent and common in the adolescent period as well and pinpoints the origin of gender violence from first adolescent relationships. This element takes us to considerate how recent gender violence studies and policies, increased also thanks to international efforts on this issue, are not bringing expected results, especially among young people. This mini-review aims to analyze the main characteristics of current gender studies and policies on dating violence, focusing on percentages with a woman-centered approach, which stresses the consequences of gender violence. Other gender studies, that consider gender as a relational product, stress the importance of integrating the analysis of gender models as a key instrument to understand the main causes of dating violence, providing new elements to develop effective policies against dating violence. Indeed, gender models of femininity and masculinity are based on a binary system, which is also a reciprocal recognition and identity system: gender models define female and male characteristics, roles, stereotypes, and expectation, being complementary and foreclosing at the same time. Recent studies on gender relationships, especially among the youth, allows us to propose a new dialog between dating violence studies and gender model studies, underling the need of a complete and complex understanding of gender structure, and of its tensions and contradictions, to put an end to gender and dating violence, through effective programs. PMID:29946282

  11. The accuracy of ultrashort echo time MRI sequences for medical additive manufacturing

    PubMed Central

    Rijkhorst, Erik-Jan; Hofman, Mark; Forouzanfar, Tymour; Wolff, Jan

    2016-01-01

    Objectives: Additively manufactured bone models, implants and drill guides are becoming increasingly popular amongst maxillofacial surgeons and dentists. To date, such constructs are commonly manufactured using CT technology that induces ionizing radiation. Recently, ultrashort echo time (UTE) MRI sequences have been developed that allow radiation-free imaging of facial bones. The aim of the present study was to assess the feasibility of UTE MRI sequences for medical additive manufacturing (AM). Methods: Three morphologically different dry human mandibles were scanned using a CT and MRI scanner. Additionally, optical scans of all three mandibles were made to acquire a “gold standard”. All CT and MRI scans were converted into Standard Tessellation Language (STL) models and geometrically compared with the gold standard. To quantify the accuracy of the AM process, the CT, MRI and gold-standard STL models of one of the mandibles were additively manufactured, optically scanned and compared with the original gold-standard STL model. Results: Geometric differences between all three CT-derived STL models and the gold standard were <1.0 mm. All three MRI-derived STL models generally presented deviations <1.5 mm in the symphyseal and mandibular area. The AM process introduced minor deviations of <0.5 mm. Conclusions: This study demonstrates that MRI using UTE sequences is a feasible alternative to CT in generating STL models of the mandible and would therefore be suitable for surgical planning and AM. Further in vivo studies are necessary to assess the usability of UTE MRI sequences in clinical settings. PMID:26943179

  12. A Moderator Model of Alcohol Use and Dating Aggression among Young Adults.

    PubMed

    Collibee, Charlene; Furman, Wyndol

    2018-03-01

    Dating aggression has been identified as a priority public health concern. Although alcohol use is a known robust risk factor for dating aggression involvement, such usage is neither necessary nor sufficient for dating aggression involvement. As such, a growing topic of interest is a better understanding of when, and for whom, alcohol use increases risk. A theoretical moderator model posits that associations between alcohol use and dating aggression involvement vary depending on both background (e.g., psychopathology) and situational (e.g., relationship characteristics) risk factors. Alcohol use is thought to be more strongly associated with dating aggression in the context of these other risk factors. Using an intensive longitudinal design, we collected six waves of data spanning 6 months from 120 participants (60 females; M age W1 = 22.44). Alcohol use and relationship risk were both associated with increases in dating aggression involvement. Consistent with a moderator model, interactions emerged between alcohol use and relationship risk for subsequent dating aggression involvement. The findings underscore the importance of alcohol use and relationship risk for the development of intervention and prevention programs.

  13. 40 CFR 60.2800 - Can reporting dates be changed?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2800 Can... dates. See § 60.19(c) for procedures to seek approval to change your reporting date. Model Rule—Title V...

  14. 40 CFR 60.2800 - Can reporting dates be changed?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emissions Guidelines and Compliance Times for Commercial and Industrial Solid Waste Incineration Units Model Rule-Recordkeeping and Reporting § 60.2800 Can... dates. See § 60.19(c) for procedures to seek approval to change your reporting date. Model Rule—Title V...

  15. Fifteen Years of ASTER Data on NASA's Terra Platform

    NASA Astrophysics Data System (ADS)

    Abrams, M.; Tsu, H.

    2014-12-01

    The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) is one of five instruments operating on NASA's Terra platform. Launched in 1999, ASTER has been acquiring data for 15 years. ASTER is a joint project between Japan's Ministry of Economy, Trade and Industry; and US NASA. Data processing and distribution are done by both organizations; a joint science team helps to define mission priorities. ASTER acquires ~550 images per day, with a 60 km swath width. A daytime acquisition is three visible bands and a backward-looking stereo band with 15 m resolution, six SWIR bands with 30 m resolution, and 5 TIR bands with 90 m resolution. Nighttime TIR-only data are routinely collected. The stereo capability has allowed the ASTER project to produce a global Digital Elevation Model (GDEM) data set, covering the earth's land surfaces from 83 degrees north to 83 degrees south, with 30 m data postings. This is the only (near-) global DEM available to all users at no charge; to date, over 28 million 1-by-1 degree DEM tiles have been distributed. As a general-purpose imaging instrument, ASTER-acquired data are used in numerous scientific disciplines, including: land use/land cover, urban monitoring, urban heat island studies, wetlands studies, agriculture monitoring, forestry, etc. Of particular emphasis has been the acquisition and analysis of data for natural hazard and disaster applications. We have been systematically acquiring images for 15,000 valley glaciers through the USGS Global Land Ice Monitoring from Space Project. The recently published Randolph Glacier Inventory, and the GLIMS book, both relied heavily on ASTER data as the basis for glaciological and climatological studies. The ASTER Volcano Archive is a unique on-line archive of thousands of daytime and nighttime ASTER images of ~1500 active glaciers, along with a growing archive of Landsat images. ASTER was scheduled to target active volcanoes at least 4 times per year, and more frequently for select volcanoes (like Mt. Etna and Hawaii). A separate processing and distribution system is operational in the US to allow rapid scheduling, acquisition, and distribution of ASTER data for natural hazards and disasters, such as forest fires, tornadoes, tsunamis, earthquakes, and floods. We work closely with other government agencies to provide this service.

  16. Olive flowering phenology variation between different cultivars in Spain and Italy: modeling analysis

    NASA Astrophysics Data System (ADS)

    Garcia-Mozo, H.; Orlandi, F.; Galan, C.; Fornaciari, M.; Romano, B.; Ruiz, L.; Diaz de La Guardia, C.; Trigo, M. M.; Chuine, I.

    2009-03-01

    Phenology data are sensitive data to identify how plants are adapted to local climate and how they respond to climatic changes. Modeling flowering phenology allows us to identify the meteorological variables determining the reproductive cycle. Phenology of temperate of woody plants is assumed to be locally adapted to climate. Nevertheless, recent research shows that local adaptation may not be an important constraint in predicting phenological responses. We analyzed variations in flowering dates of Olea europaea L. at different sites of Spain and Italy, testing for a genetic differentiation of flowering phenology among olive varieties to estimate whether local modeling is necessary for olive or not. We build models for the onset and peak dates flowering in different sites of Andalusia and Puglia. Process-based phenological models using temperature as input variable and photoperiod as the threshold date to start temperature accumulation were developed to predict both dates. Our results confirm and update previous results that indicated an advance in olive onset dates. The results indicate that both internal and external validity were higher in the models that used the photoperiod as an indicator to start to cumulate temperature. The use of the unified model for modeling the start and peak dates in the different localities provides standardized results for the comparative study. The use of regional models grouping localities by varieties and climate similarities indicate that local adaptation would not be an important factor in predicting olive phenological responses face to the global temperature increase.

  17. Davenport Ranges, Northern Territory, Australia, SRTM Shaded Relief and Colored Height

    NASA Technical Reports Server (NTRS)

    2005-01-01

    The Davenport Ranges of central Australia have been inferred to be among the oldest persisting landforms on Earth, founded on the belief that the interior of Australia has been tectonically stable for at least 700 million years. New rock age dating techniques indicate that substantial erosion has probably occurred over that time period and that the landforms are not nearly that old, but landscape evolution certainly occurs much slower here (at least now) than is typical across Earth's surface.

    Regardless of their antiquity, the Davenport Ranges exhibit a striking landform pattern as shown in this display of elevation data from the Shuttle Radar Topography Mission (SRTM). Quartzites and other erosion resistant strata form ridges within anticlinal (arched up) and synclinal (arched down) ovals and zigzags. These structures, if not the landforms, likely date back at least hundreds of millions of years, to a time when tectonic forces were active. Maximum local relief is only about 60 meters (about 200 feet), which is enough to contrast greatly with the extremely low relief surrounding terrain.

    Two visualization methods were combined to produce this image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the northeast-southwest (image top to bottom) direction, so that northeast slopes appear bright and southwest slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations.

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect 3-D measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter (approximately 200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Geospatial-Intelligence Agency (NGA) of the U.S. Department of Defense and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, Calif., for NASA's Earth Science Enterprise, Washington, D.C.

    Size: 270 kilometers (168 miles) by 145 kilometers (90 miles) Location: 20.9 degrees South latitude, 134.9 degrees East longitude Orientation: Northeast toward the top Image Data: Shaded and colored SRTM elevation model Date Acquired: February 2000

  18. Open Rotor Test Status

    NASA Technical Reports Server (NTRS)

    VanZante, Dale E.

    2010-01-01

    Testing of low noise, counter-rotating open rotor propulsion concepts has been ongoing at Glenn Research Center in collaboration with General Electric Company. The presentation is an overview of the testing that has been completed to date and previews the upcoming test entries. The NASA Environmentally Responsible Aviation Project Diagnostics entry is the most recent to finish. That test entry included acoustic phased array, pressure sensitive paint, particle image velocimetry, pylon installed measurements and acoustic shielding measurements. A preview of the data to be acquired in the 8x6 high-speed wind tunnel is also included.

  19. A prospectus for Thematic Mapper research in the Earth sciences

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Earth science applications of Thematic Mapper (TM) imagery are discussed. Prospective research themes are defined in a general sense in relation to the technical measurement capabilities of the TM and the various types of Earth information that can potentially be derived from multispectral TM imagery. An overview of the system developed to acquire and reduce TM data is presented. The technical capabilities of this system are presented in detail. The orbital performance of the TM sensor is described, based upon the analysis of LANDSAT 4 and 5 TM data collected to date.

  20. Sampling the Uppermost Surface of Airless Bodies

    NASA Technical Reports Server (NTRS)

    Noble, S. K.; Keller, L. P.; Christoffersen, R.

    2011-01-01

    The uppermost surface of an airless body is a critical source of ground-truth information for the various remote sensing techniques that only penetrate nanometers to micrometers into the surface. Such samples will also be vital for understanding conditions at the surface and acquiring information about how the body interacts with its environment, including solar wind interaction, grain charging and levitation [1]. Sampling the uppermost surface while preserving its structure (e.g. porosity, grain-to-grain contacts) however, is a daunting task that has not been achieved on any sample return mission to date.

  1. Development of Matched (migratory Analytical Time Change Easy Detection) Method for Satellite-Tracked Migratory Birds

    NASA Astrophysics Data System (ADS)

    Doko, Tomoko; Chen, Wenbo; Higuchi, Hiroyoshi

    2016-06-01

    Satellite tracking technology has been used to reveal the migration patterns and flyways of migratory birds. In general, bird migration can be classified according to migration status. These statuses include the wintering period, spring migration, breeding period, and autumn migration. To determine the migration status, periods of these statuses should be individually determined, but there is no objective method to define 'a threshold date' for when an individual bird changes its status. The research objective is to develop an effective and objective method to determine threshold dates of migration status based on satellite-tracked data. The developed method was named the "MATCHED (Migratory Analytical Time Change Easy Detection) method". In order to demonstrate the method, data acquired from satellite-tracked Tundra Swans were used. MATCHED method is composed by six steps: 1) dataset preparation, 2) time frame creation, 3) automatic identification, 4) visualization of change points, 5) interpretation, and 6) manual correction. Accuracy was tested. In general, MATCHED method was proved powerful to identify the change points between migration status as well as stopovers. Nevertheless, identifying "exact" threshold dates is still challenging. Limitation and application of this method was discussed.

  2. Modelling of Peach Tree (Prunus persica) Full Blooming Dates Using APCC MME Seasonal Forecasts

    NASA Astrophysics Data System (ADS)

    Chun, Jong; Kim, Sung; Lee, Hyojin; Han, Hyun-Hee; Son, In-Chang; Cho, Kyung Hwa

    2016-04-01

    Due to global warming, recently, bud-burst and flowering dates of fruit crops have become earlier and the abnormal climate increases the variabilities of temperature in spring, suggesting that the risk of frost damage has increased. However, the full blooming date prediction model for peach tree used by the Rural Developmental Administration (RDA) were developed using only one cultivar (Youmyeong) and observations from a station (Suwon). This model might not adequately reflect the characteristics of peach cultivars or local orchards. the objectives of this study were to develops the site-and cultivar-specific blooming date prediction models for major peach cultivation regions and cultivars and presents a framework for applications of the APEC Climate Center Multimodel Ensemble (APCC MME) seasonal datasets.Developmental rate (DVR), and Sequential dormancy models (Chill day, New chill day, and fraction-time models) were used to develop the locally tailored full blooming date prediction models for major peach cultivars. For the development of these models, bud-burst and full blooming dates of peach tree for 5 cultivars (Cheonhong, Youmyeong, Changbangjosaeng, Cheonjoongdo, and Janghowon) were collected from the 6 major peach cultivation sites: Chuncheon, Suwon, Cheongwon, Cheongdo, Naju, and Jinju. For the chill day model, those measures for the entire dataset regardless the location and cultivar were 2.31%, 0.79, and 3.36 day for MAPE, R2, RMSE, respectively. For the new chill day model, those values (2.19%, 0.82, and 3.16 day for MAPE, R2, RMSE, respectively) were slightly better than those of the chill day model. The model results showed that the new chill day model was found slightly highest performance than others. Based on the considerations of the predictability of the statistical downscaling method and the observed periods of the full blooming dates at each site, we determined that the APCC MME seasonal datasets were applied for the new chill day model for the Changbangjosaeng and Youmyeong cultivars at the Suwon site. The values of the goodness-of-fit measures using the selected synthetic daily maximum and minimum temperatures reflecting APCC MME seasonal datasets and selected were worse than those using those collected from the Suwon station. It is concluded that further work was recommended that the predictability of APCC MME seasonal forecasts should be improved to reduce the prediction errors of full blooming dates of peach trees.

  3. Characterizing GEO Titan IIIC Transtage Fragmentations Using Ground-Based and Telescopic Measurements

    NASA Technical Reports Server (NTRS)

    Cowardin, H.

    2017-01-01

    In a continued effort to better characterize the Geosynchronous Orbit (GEO) environment, NASA's Orbital Debris Program Office (ODPO) utilizes various ground-based optical assets to acquire photometric and spectral data of known debris associated with fragmentations in or near GEO. The Titan IIIC Transtage upper stage is known to have fragmented four times. Two of the four fragmentations were in GEO while a third Transtage fragmented in GEO transfer orbit. The forth fragmentation occurred in Low Earth Orbit. In order to better assess and characterize these fragmentations, the NASA ODPO acquired a Titan Transtage test and display article previously in the custody of the 309th Aerospace Maintenance and Regeneration Group (AMARG) in Tucson, Arizona. After initial inspections at AMARG demonstrated that the test article was of sufficient fidelity to be of interest, the test article was brought to JSC to continue material analysis and historical documentation of the Titan Transtage. The Transtage has been subject to two separate spectral measurement campaigns to characterize the reflectance spectroscopy of historical aerospace materials. These data have been incorporated into the NASA Spectral Database, the goal being to enable comparison with telescopic data and potential material identification. A LIDAR scan has been completed and a scale model has been created for use in the Optical Measurement Center for photometric analysis of an intact Transtage, including a BRDF. An historical overview of the Titan IIIC Transtage, the current analysis that has been done to date, and the future work to be completed in support of characterizing the GEO and near GEO orbital debris environment will be discussed in the subsequent presentation.

  4. Association of Temporal Variations in Staffing With Hospital-Acquired Pressure Injury in Military Hospitals.

    PubMed

    Patrician, Patricia A; McCarthy, Mary S; Swiger, Pauline; Raju, Dheeraj; Breckenridge-Sproat, Sara; Su, Xiaogang; Randall, Kelly H; Loan, Lori A

    2017-04-01

    To more precisely evaluate the effects of nurse staffing on hospital-acquired pressure injury (HAPI) development, data on nursing care hours per patient day (NCHPPD), nursing skill mix, patient turnover (i.e., admissions, transfers, and discharges), and patient acuity were merged with patient information from pressure injury prevalence surveys that were collected annually for the Military Nursing Outcomes Database (MilNOD) project. The MilNOD included staffing and adverse events from 56 medical-surgical, stepdown, and critical care units in 13 military hospitals over a 4-year-period. Data on 1,643 patients were analyzed with Cox proportional hazards models and generalized estimating equations. Staffing was not associated with pressure injuries in stepdown or critical care patients. However, among the 1,104 medical-surgical patients, higher licensed practical nurse (LPN) nursing care hours per patient day (NCHPPD) 3 days and 1 week prior to the HAPI discovery date were associated with fewer HAPI (HR 0.27, p < .001), after controlling for patient age, Braden mobility score, and albumin level. Neither total staff number, nor RN NCHPPD, nor the proportion of staff who were RNs (RN skill mix) were associated with HAPI. These findings suggest that on military medical-surgical units, LPNs play a major role in HAPI prevention. Although the national trend in acute care is to staff hospital units with more RNs and patient care technicians, and fewer LPNs, hospitals should reconsider LPNs as valuable members of the nursing care team. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  5. Experimental Investigation of Rotating Stall in a Research Multistage Axial Compressor

    NASA Technical Reports Server (NTRS)

    Lepicovsky, Jan; Braunscheidel, Edward P.; Welch, Gerard E.

    2007-01-01

    A collection of experimental data acquired in the NASA low-speed multistage axial compressor while operated in rotating stall is presented in this paper. The compressor was instrumented with high-response wall pressure modules and a static pressure disc probe for in-flow measurement, and a split-fiber probe for simultaneous measurements of velocity magnitude and flow direction. The data acquired to-date have indicated that a single fully developed stall cell rotates about the flow annulus at 50.6% of the rotor speed. The stall phenomenon is substantially periodic at a fixed frequency of 8.29 Hz. It was determined that the rotating stall cell extends throughout the entire compressor, primarily in the axial direction. Spanwise distributions of the instantaneous absolute flow angle, axial and tangential velocity components, and static pressure acquired behind the first rotor are presented in the form of contour plots to visualize different patterns in the outer (midspan to casing) and inner (hub to mid-span) flow annuli during rotating stall. In most of the cases observed, the rotating stall started with a single cell. On occasion, rotating stall started with two emerging stall cells. The root cause of the variable stall cell count is unknown, but is not attributed to operating procedures.

  6. The impact of parental and peer social support on dating violence perpetration and victimization among female adolescents: a longitudinal study.

    PubMed

    Richards, Tara N; Branch, Kathryn A; Ray, Katherine

    2014-01-01

    Little is known about the role social support may play in reducing the risk of adolescent dating violence perpetration and victimization. This study is a longitudinal analysis of the independent impact of social support from friends and parents on the risk of emotional and physical dating violence perpetration and victimization among a large sample of female youth (n = 346). Findings indicate that 22% of the sample indicated perpetrating physical dating violence against a partner, whereas almost 16% revealed being the victim of physical dating violence; 34% of the sample indicated perpetrating emotional dating violence against a partner, whereas almost 39% revealed being the victim of emotional dating violence. Negative binomial regression models indicated that increased levels of support from friends at Time 1 was associated with significantly less physical and emotional dating violence perpetration and emotional (but not physical) dating violence victimization at Time 2. Parental support was not significantly related to dating violence in any model. Implications for dating violence curriculum and future research are addressed.

  7. The Economics of Online Dating: A Course in Economic Modeling

    ERIC Educational Resources Information Center

    Monaco, Andrew J.

    2018-01-01

    The author discusses the development of a unique course, The Economics of Online Dating. The course is an upper-level undergraduate course that combines intensive discussion, peer review, and economic theory to teach modeling skills to undergraduates. The course uses the framework of "online dating," interpreted broadly, as a point of…

  8. Calibrating a hydraulic model using water levels derived from time series high-resolution Radarsat-2 synthetic aperture radar images and elevation data

    NASA Astrophysics Data System (ADS)

    Trudel, M.; Desrochers, N.; Leconte, R.

    2017-12-01

    Knowledge of water extent (WE) and level (WL) of rivers is necessary to calibrate and validate hydraulic models and thus to better simulate and forecast floods. Synthetic aperture radar (SAR) has demonstrated its potential for delineating water bodies, as backscattering of water is much lower than that of other natural surfaces. The ability of SAR to obtain information despite cloud cover makes it an interesting tool for temporal monitoring of water bodies. The delineation of WE combined with a high-resolution digital terrain model (DTM) allows extracting WL. However, most research using SAR data to calibrate hydraulic models has been carried out using one or two images. The objectives of this study is to use WL derived from time series high resolution Radarsat-2 SAR images for the calibration of a 1-D hydraulic model (HEC-RAS). Twenty high-resolution (5 m) Radarsat-2 images were acquired over a 40 km reach of the Athabasca River, in northern Alberta, Canada, between 2012 and 2016, covering both low and high flow regimes. A high-resolution (2m) DTM was generated combining information from LIDAR data and bathymetry acquired between 2008 and 2016 by boat surveying. The HEC-RAS model was implemented on the Athabasca River to simulate WL using cross-sections spaced by 100 m. An image histogram thresholding method was applied on each Radarsat-2 image to derive WE. WE were then compared against each cross-section to identify those were the slope of the banks is not too abrupt and therefore amenable to extract WL. 139 observations of WL at different locations along the river reach and with streamflow measurements were used to calibrate the HEC-RAS model. The RMSE between SAR-derived and simulated WL is under 0.35 m. Validation was performed using in situ observations of WL measured in 2008, 2012 and 2016. The RMSE between the simulated water levels calibrated with SAR images and in situ observations is less than 0.20 m. In addition, a critical success index (CSI) was performed to compare the WE simulated by HEC-RAS and that derived from SARs images. The CSI is higher than 0.85 for each date, which means that simulated WE is highly similar to the WE derived from SARs images. Thereby, the results of our analysis indicate that calibration of a hydraulic model can be performed from WL derived from time series of high-resolution SAR images.

  9. A novel left heart simulator for the multi-modality characterization of native mitral valve geometry and fluid mechanics.

    PubMed

    Rabbah, Jean-Pierre; Saikrishnan, Neelakantan; Yoganathan, Ajit P

    2013-02-01

    Numerical models of the mitral valve have been used to elucidate mitral valve function and mechanics. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental validation. As computational solvers vary considerably, experimental benchmark data are critically important to ensure model accuracy. In this study, a novel left heart simulator was designed specifically for the validation of numerical mitral valve models. Several distinct experimental techniques were collectively performed to resolve mitral valve geometry and hemodynamics. In particular, micro-computed tomography was used to obtain accurate and high-resolution (39 μm voxel) native valvular anatomy, which included the mitral leaflets, chordae tendinae, and papillary muscles. Three-dimensional echocardiography was used to obtain systolic leaflet geometry. Stereoscopic digital particle image velocimetry provided all three components of fluid velocity through the mitral valve, resolved every 25 ms in the cardiac cycle. A strong central filling jet (V ~ 0.6 m/s) was observed during peak systole with minimal out-of-plane velocities. In addition, physiologic hemodynamic boundary conditions were defined and all data were synchronously acquired through a central trigger. Finally, the simulator is a precisely controlled environment, in which flow conditions and geometry can be systematically prescribed and resultant valvular function and hemodynamics assessed. Thus, this work represents the first comprehensive database of high fidelity experimental data, critical for extensive validation of mitral valve fluid structure interaction simulations.

  10. A Novel Left Heart Simulator for the Multi-modality Characterization of Native Mitral Valve Geometry and Fluid Mechanics

    PubMed Central

    Rabbah, Jean-Pierre; Saikrishnan, Neelakantan; Yoganathan, Ajit P.

    2012-01-01

    Numerical models of the mitral valve have been used to elucidate mitral valve function and mechanics. These models have evolved from simple two-dimensional approximations to complex three-dimensional fully coupled fluid structure interaction models. However, to date these models lack direct one-to-one experimental validation. As computational solvers vary considerably, experimental benchmark data are critically important to ensure model accuracy. In this study, a novel left heart simulator was designed specifically for the validation of numerical mitral valve models. Several distinct experimental techniques were collectively performed to resolve mitral valve geometry and hemodynamics. In particular, micro-computed tomography was used to obtain accurate and high-resolution (39 µm voxel) native valvular anatomy, which included the mitral leaflets, chordae tendinae, and papillary muscles. Threedimensional echocardiography was used to obtain systolic leaflet geometry for direct comparison of resultant leaflet kinematics. Stereoscopic digital particle image velocimetry provided all three components of fluid velocity through the mitral valve, resolved every 25 ms in the cardiac cycle. A strong central filling jet was observed during peak systole, with minimal out-of-plane velocities (V~0.6m/s). In addition, physiologic hemodynamic boundary conditions were defined and all data were synchronously acquired through a central trigger. Finally, the simulator is a precisely controlled environment, in which flow conditions and geometry can be systematically prescribed and resultant valvular function and hemodynamics assessed. Thus, these data represent the first comprehensive database of high fidelity experimental data, critical for extensive validation of mitral valve fluid structure interaction simulations. PMID:22965640

  11. U-Pb Dating of Calcite by LA-ICPMS

    NASA Astrophysics Data System (ADS)

    Hacker, B. R.; Kylander-Clark, A. R.; Holder, R. M.; Nuriel, P.

    2016-12-01

    An emerging frontier area in geochronology is U-Pb dating of carbonate minerals by laser-ablation inductively coupled plasma mass spectrometry (LA-ICPMS). The spate of papers over the last few years applying LA-ICPMS to carbonate dating stems from the capability of LA-ICPMS to deal with the variable, and often low, U/Pb ratios of carbonate. LA-ICPMS is an excellent tool for efficiently screening out samples with low U/Pb ratios and provides the ability to measure many spots with different U/Pb ratios and obtain dates free of assumptions about the composition of common Pb. Because this technique is in its infancy, important questions remain. What percentage of carbonate samples have high enough U/Pbc ratios that they can be dated? What percentage of samples yield isochronous datasets? What are the limits on precision and accuracy of carbonate U/Pb dates? What is the best analytical method in the absence of isotopically homogeneous reference materials? Through the generosity of our colleagues we have acquired 8 reference materials ranging in age from 3 to 250 Ma. We have analyzed 125 unknowns from a variety of locations using a 193 nm ns laser with an 80-100 μm spot and a Nu Plasma HR-ES. We measure 207Pb/206Pb using NIST 614 glass and then calculate a 206Pb/238U correction factor based on the measured vs. known ages of the reference materials. Sixty of these samples ( 50%) have high enough U/Pb ratios that they can be dated. There is great heterogeneity among the sample suites: some have no datable samples, whereas one suite of 68 samples yielded 53 datable rocks. Of the samples with high U/Pbc ratios, a majority yielded isochronous U-Pb data, indicating that the U-Pb system closed at a given time and was not subsequently disturbed.

  12. Forward Monte Carlo Computations of Polarized Microwave Radiation

    NASA Technical Reports Server (NTRS)

    Battaglia, A.; Kummerow, C.

    2000-01-01

    Microwave radiative transfer computations continue to acquire greater importance as the emphasis in remote sensing shifts towards the understanding of microphysical properties of clouds and with these to better understand the non linear relation between rainfall rates and satellite-observed radiance. A first step toward realistic radiative simulations has been the introduction of techniques capable of treating 3-dimensional geometry being generated by ever more sophisticated cloud resolving models. To date, a series of numerical codes have been developed to treat spherical and randomly oriented axisymmetric particles. Backward and backward-forward Monte Carlo methods are, indeed, efficient in this field. These methods, however, cannot deal properly with oriented particles, which seem to play an important role in polarization signatures over stratiform precipitation. Moreover, beyond the polarization channel, the next generation of fully polarimetric radiometers challenges us to better understand the behavior of the last two Stokes parameters as well. In order to solve the vector radiative transfer equation, one-dimensional numerical models have been developed, These codes, unfortunately, consider the atmosphere as horizontally homogeneous with horizontally infinite plane parallel layers. The next development step for microwave radiative transfer codes must be fully polarized 3-D methods. Recently a 3-D polarized radiative transfer model based on the discrete ordinate method was presented. A forward MC code was developed that treats oriented nonspherical hydrometeors, but only for plane-parallel situations.

  13. Paleomagnetism of the Red Dog Zn-Pb massive sulfide deposit in northern Alaska

    USGS Publications Warehouse

    Lewchuk, Michael T.; Leach, D.L.; Kelley, K.D.; Symons, David T. A.

    2004-01-01

    Paleomagnetic methods have isolated two ancient magnetizations in and around the Paleozoic shale-hosted Red Dog ore deposit in northern Alaska. A high-latitude, westerly magnetization carried by magnetite, termed characteristic remanent magnetization A, was found in rocks that have barite and/or substantial quartz replacement of barite. An intermediate- to low-latitude, southerly magnetization (characteristic remanent magnetization B) is carried by pyrrhotite and was found in rocks dominated by galena and sphalerite. The ages the two components are constrained by their relationship with geochemistry, radiometric age dating, and hypotheses for the Mesozoic tectonic history of the Brooks Range. Characteristic remanent magnetization A fails the fold test so it must postdate the end of Brookian orogenesis (??? 150 Ma). It is always found with replacement quartz that has a radiometric date (white mica from a vug, 39Ar/40Ar) of 126 Ma. The paleolatitude for characteristic remanent magnetization B is too shallow to be Mesozoic or younger, regardless of the model for the tectonic origin of northern Alaska, and must predate Brookian orogenesis. Geologic mapping suggests that most of the ore is syngenetic, formed at 330 to 340 Ma, and a radiometric date (Re-Os on pyrite) yields an age of 338 Ma. Since characteristic remanent magnetization B predates deformation, is found in mineralized rocks and is carried by pyrrhotite, it was probably acquired during the mineralizing process as well. The combined radiometric ages and paleomagnetic data sets can be best interpreted by assuming that northern Alaska was part of an accreted terrane that was translated northward by about 30?? into its current location relative to the rest of North America and then rotated counterclockwise by 50?? to 70??. This tectonic interpretation yields plausible magnetization ages for both characteristic remanent magnetization A and B. Geologic evidence, isotopic ages, and paleomagnetic data indicate formation of the deposit at a paleolatitude that is much lower than today. ?? 2004 by Economic Geology.

  14. Language-Independent and Language-Specific Aspects of Early Literacy: An Evaluation of the Common Underlying Proficiency Model

    ERIC Educational Resources Information Center

    Goodrich, J. Marc; Lonigan, Christopher J.

    2017-01-01

    According to the common underlying proficiency model (Cummins, 1981), as children acquire academic knowledge and skills in their first language, they also acquire language-independent information about those skills that can be applied when learning a second language. The purpose of this study was to evaluate the relevance of the common underlying…

  15. Modeling as a Technique for Promoting Classroom Learning and Prosocial Behavior. Theoretical Paper No. 39.

    ERIC Educational Resources Information Center

    Frayer, Dorothy A.; Klausmeier, Herbert J.

    Research has shown that a behavior may be acquired through observing and imitating a model. A behavior which has already been acquired may be inhibited, disinhibited, or elicited by observing and imitating. A definition of imitation is given, and the effects of imitation on learning and performance are summarized. Research on factors which affect…

  16. Evaluation of the Protective Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against Marburg Hemorrhagic Fever in Nonhuman Primate Models

    DTIC Science & Technology

    2007-01-19

    fever in Nonhuman Primate Models" Date d?JO )oi Date )&*7 Date Dissertation and Abstract Approved: Robert Friedm ,M.D. Department of Pathology Committee...thesis manuscript entitled: "Evaluation of the Protective Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against Marburg Hemorrhagic fever ...stomatitis virus vectors against Marburg hemorrhagic fever in nonhuman primate models By Kathleen Daddario-DiCaprio Dissertation

  17. Estimating Divergence Dates and Substitution Rates in the Drosophila Phylogeny

    PubMed Central

    Obbard, Darren J.; Maclennan, John; Kim, Kang-Wook; Rambaut, Andrew; O’Grady, Patrick M.; Jiggins, Francis M.

    2012-01-01

    An absolute timescale for evolution is essential if we are to associate evolutionary phenomena, such as adaptation or speciation, with potential causes, such as geological activity or climatic change. Timescales in most phylogenetic studies use geologically dated fossils or phylogeographic events as calibration points, but more recently, it has also become possible to use experimentally derived estimates of the mutation rate as a proxy for substitution rates. The large radiation of drosophilid taxa endemic to the Hawaiian islands has provided multiple calibration points for the Drosophila phylogeny, thanks to the "conveyor belt" process by which this archipelago forms and is colonized by species. However, published date estimates for key nodes in the Drosophila phylogeny vary widely, and many are based on simplistic models of colonization and coalescence or on estimates of island age that are not current. In this study, we use new sequence data from seven species of Hawaiian Drosophila to examine a range of explicit coalescent models and estimate substitution rates. We use these rates, along with a published experimentally determined mutation rate, to date key events in drosophilid evolution. Surprisingly, our estimate for the date for the most recent common ancestor of the genus Drosophila based on mutation rate (25–40 Ma) is closer to being compatible with independent fossil-derived dates (20–50 Ma) than are most of the Hawaiian-calibration models and also has smaller uncertainty. We find that Hawaiian-calibrated dates are extremely sensitive to model choice and give rise to point estimates that range between 26 and 192 Ma, depending on the details of the model. Potential problems with the Hawaiian calibration may arise from systematic variation in the molecular clock due to the long generation time of Hawaiian Drosophila compared with other Drosophila and/or uncertainty in linking island formation dates with colonization dates. As either source of error will bias estimates of divergence time, we suggest mutation rate estimates be used until better models are available. PMID:22683811

  18. Topology, divergence dates, and macroevolutionary inferences vary between different tip-dating approaches applied to fossil theropods (Dinosauria).

    PubMed

    Bapst, D W; Wright, A M; Matzke, N J; Lloyd, G T

    2016-07-01

    Dated phylogenies of fossil taxa allow palaeobiologists to estimate the timing of major divergences and placement of extinct lineages, and to test macroevolutionary hypotheses. Recently developed Bayesian 'tip-dating' methods simultaneously infer and date the branching relationships among fossil taxa, and infer putative ancestral relationships. Using a previously published dataset for extinct theropod dinosaurs, we contrast the dated relationships inferred by several tip-dating approaches and evaluate potential downstream effects on phylogenetic comparative methods. We also compare tip-dating analyses to maximum-parsimony trees time-scaled via alternative a posteriori approaches including via the probabilistic cal3 method. Among tip-dating analyses, we find opposing but strongly supported relationships, despite similarity in inferred ancestors. Overall, tip-dating methods infer divergence dates often millions (or tens of millions) of years older than the earliest stratigraphic appearance of that clade. Model-comparison analyses of the pattern of body-size evolution found that the support for evolutionary mode can vary across and between tree samples from cal3 and tip-dating approaches. These differences suggest that model and software choice in dating analyses can have a substantial impact on the dated phylogenies obtained and broader evolutionary inferences. © 2016 The Author(s).

  19. Joint 3D Inversion of ZTEM Airborne and Ground MT Data with Application to Geothermal Exploration

    NASA Astrophysics Data System (ADS)

    Wannamaker, P. E.; Maris, V.; Kordy, M. A.

    2017-12-01

    ZTEM is an airborne electromagnetic (EM) geophysical technique developed by Geotech Inc® where naturally propagated EM fields originating with regional and global lightning discharges (sferics) are measured as a means of inferring subsurface electrical resistivity structure. A helicopter-borne coil platform (bird) measuring the vertical component of magnetic (H) field variations along a flown profile is referenced to a pair of horizontal coils at a fixed location on the ground in order to estimate a tensor H-field transfer function. The ZTEM method is distinct from the traditional magnetotelluric (MT) method in that the electric (E) fields are not considered because of the technological challenge of measuring E-fields in the dielectric air medium. This can lend some non-uniqueness to ZTEM interpretation because a range of conductivity structures in the earth depending upon an assumed background earth resistivity model can fit ZTEM data to within tolerance. MT data do not suffer this particular problem, but they are cumbersome to acquire in their common need for land-based transport often in near-roadless areas and for laying out and digging the electrodes and H coils. The complementary nature of ZTEM and MT logistics and resolution has motivated development of schemes to acquire appropriate amounts of each data type in a single survey and to produce an earth image through joint inversion. In particular, consideration is given to surveys where only sparse MT soundings are needed to drastically reduce the non-uniqueness associated with background uncertainty while straining logistics minimally. Synthetic and field data are analysed using 2D and 3D finite element platforms developed for this purpose. Results to date suggest that indeed dense ZTEM surveys can provide detailed heterogeneous model images with large-scale averages constrained by a modest number of MT soundings. Further research is needed in determining the allowable degree of MT sparseness and the relative weighting of the two data sets in joint inversion.

  20. Multivariate decoding of cerebral blood flow measures in a clinical model of on-going postsurgical pain.

    PubMed

    O'Muircheartaigh, Jonathan; Marquand, Andre; Hodkinson, Duncan J; Krause, Kristina; Khawaja, Nadine; Renton, Tara F; Huggins, John P; Vennart, William; Williams, Steven C R; Howard, Matthew A

    2015-02-01

    Recent reports of multivariate machine learning (ML) techniques have highlighted their potential use to detect prognostic and diagnostic markers of pain. However, applications to date have focussed on acute experimental nociceptive stimuli rather than clinically relevant pain states. These reports have coincided with others describing the application of arterial spin labeling (ASL) to detect changes in regional cerebral blood flow (rCBF) in patients with on-going clinical pain. We combined these acquisition and analysis methodologies in a well-characterized postsurgical pain model. The principal aims were (1) to assess the classification accuracy of rCBF indices acquired prior to and following surgical intervention and (2) to optimise the amount of data required to maintain accurate classification. Twenty male volunteers, requiring bilateral, lower jaw third molar extraction (TME), underwent ASL examination prior to and following individual left and right TME, representing presurgical and postsurgical states, respectively. Six ASL time points were acquired at each exam. Each ASL image was preceded by visual analogue scale assessments of alertness and subjective pain experiences. Using all data from all sessions, an independent Gaussian Process binary classifier successfully discriminated postsurgical from presurgical states with 94.73% accuracy; over 80% accuracy could be achieved using half of the data (equivalent to 15 min scan time). This work demonstrates the concept and feasibility of time-efficient, probabilistic prediction of clinically relevant pain at the individual level. We discuss the potential of ML techniques to impact on the search for novel approaches to diagnosis, management, and treatment to complement conventional patient self-reporting. © 2014 The Authors. Human Brain Mapping Published by Wiley Periodicals, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

  1. Comparative assessment of knee joint models used in multi-body kinematics optimisation for soft tissue artefact compensation.

    PubMed

    Richard, Vincent; Cappozzo, Aurelio; Dumas, Raphaël

    2017-09-06

    Estimating joint kinematics from skin-marker trajectories recorded using stereophotogrammetry is complicated by soft tissue artefact (STA), an inexorable source of error. One solution is to use a bone pose estimator based on multi-body kinematics optimisation (MKO) embedding joint constraints to compensate for STA. However, there is some debate over the effectiveness of this method. The present study aimed to quantitatively assess the degree of agreement between reference (i.e., artefact-free) knee joint kinematics and the same kinematics estimated using MKO embedding six different knee joint models. The following motor tasks were assessed: level walking, hopping, cutting, running, sit-to-stand, and step-up. Reference knee kinematics was taken from pin-marker or biplane fluoroscopic data acquired concurrently with skin-marker data, made available by the respective authors. For each motor task, Bland-Altman analysis revealed that the performance of MKO varied according to the joint model used, with a wide discrepancy in results across degrees of freedom (DoFs), models and motor tasks (with a bias between -10.2° and 13.2° and between -10.2mm and 7.2mm, and with a confidence interval up to ±14.8° and ±11.1mm, for rotation and displacement, respectively). It can be concluded that, while MKO might occasionally improve kinematics estimation, as implemented to date it does not represent a reliable solution to the STA issue. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. D Virtual Reconstruction of AN Urban Historical Space: a Consideration on the Method

    NASA Astrophysics Data System (ADS)

    Galizia, M.; Santagati, C.

    2011-09-01

    Urban historical spaces are often characterized by a variety of shapes, geometries, volumes, materials. Their virtual reconstruction requires a critical approach in terms of acquired data's density, timing optimization, final product's quality and slimness. The research team has focused its attention on the study on Francesco Neglia square (previously named Saint Thomas square) in Enna. This square is an urban space fronted by architectures which present historical and stylistic differences. For example you can find the Saint Thomas'church belfry (in aragounese-catalan stile dated XIV century) and the porch, the Anime Sante baroque's church (XVII century), Saint Mary of the Grace's nunnery (XVIII century) and as well as some civil buildings of minor importance built in the mid twentieth century. The research has compared two different modeling tools approaches: the first one is based on the construction of triangulated surfaces which are segmented and simplified; the second one is based on the detection of surfaces geometrical features, the extraction of the more significant profiles by using a software dedicated to the elaboration of cloud points and the subsequent mathematical reconstruction by using a 3d modelling software. The following step was aimed to process the virtual reconstruction of urban scene by assembling the single optimized models. This work highlighted the importance of the image of the operator and of its cultural contribution, essential to recognize geometries which generates surfaces in order to create high quality semantic models.

  3. I want you to pretend to be sincere.

    PubMed

    Hynes, Julia

    2016-12-01

    Medical education has changed dramatically since the inception of this journal 50 years ago and is indeed a work in progress: there is now heavy emphasis on the character of the physician, in particular, and professionalism, in general. The subjects of communications skills and the teaching of sincerity, empathy and compassion are relative newcomers to the stage: they are not even as old as this journal itself. Nevertheless, these topics arose in an ancient debate dating from classical antiquity. 'Can we teach virtue?' Plato wondered in the Meno. Not exactly, he concluded. Aristotle believed that acquirement of the virtues enables one to attain the human good, which, in turn, spills over to any profession in which the human being decides to engage. Aristotle, along with his successor, Thomas Aquinas, the 13th century philosopher, argued that the virtues cannot be taught but only acquired, with practice and time, in the real situation. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

  4. Quickbird Geometry Report for Summer 2003

    NASA Technical Reports Server (NTRS)

    Darbha, Ravikanth; Helder, Dennis; Choi, Taeyoung

    2005-01-01

    Digital Globe provides for general use 2.4 m multi-spectral and 0.7 m panchromatic imagery acquired by the Quickbird satellite. This geometrically corrected imagery was obtained as standard and orthorectified products; the difference between the two products is primarily in the degree of geometric accuracy that Digital Globe claims. For both products, every image pixel contains estimated sets of Northing/Easting and lat/long coordinates accessible through an image display application such as ENVI. Ground processing was performed by Digital Globe using the ADP 2.1 version of their system. Analysis conducted at South Dakota State University attempted to verify the geometric accuracy of standard and orthorectified Quickbird imagery to determine if specifications for the NASA Science Data Purchase (SDP) were met. These specifications are in Table 1 of Appendix 1. In this analysis, we had approximately 90 Ground Control Points (varies depending on scene size on each date), uniformly distributed over the Brookings, SD, area, from 4 Quickbird scenes acquired August 23, September 15, and October 21 of 2003.

  5. How Children Learn to Navigate the Symbolic World of Pictures: The Importance of the Artist's Mind and Differentiating Picture Modalities.

    PubMed

    Allen, M L; Armitage, E

    2017-01-01

    Pictures offer a unique and essential contribution to our lives, both in terms of aesthetic pleasure and links to symbolic thought. As such, psychologists have devoted significant time to investigating how children acquire an understanding of pictures. This chapter focuses on two particular facets of this development: the role of the artist and the importance of picture modality. First, we review work that has focused on tracking children's ability to (a) map the relationship between the mental state of the artist and their pictures, and (b) incorporate such considerations into their evaluations of pictures. Drawing these literatures together provides an up-to-date account of how children acquire a mentalistic understanding of pictures. Second, we argue that a mature theory of pictures must enable children to distinguish between different picture types (e.g., photographs vs drawings), and therefore that picture modality should be incorporated into existing theoretical accounts of pictorial development. © 2017 Elsevier Inc. All rights reserved.

  6. Historical record of Landsat global coverage

    USGS Publications Warehouse

    Goward, Samuel; Arvidson, Terry; Williams, Darrel; Faundeen, John; Irons, James; Franks, Shannon

    2006-01-01

    The long-term, 34+ year record of global Landsat remote sensing data is a critical resource to study the Earth system and human impacts on this system. The National Satellite Land Remote Sensing Data Archive (NSLRSDA) is charged by public law to: “maintain a permanent, comprehensive Government archive of global Landsat and other land remote sensing data for long-term monitoring and study of the changing global environment” (U.S. Congress, 1992). The advisory committee for NSLRSDA requested a detailed analysis of observation coverage within the U.S. Landsat holdings, as well as that acquired and held by International Cooperator (IC) stations. Our analyses, to date, have found gaps of varying magnitude in U.S. holdings of Landsat global coverage data, which appear to reflect technical or administrative variations in mission operations. In many cases it may be possible to partially fill these gaps in U.S. holdings through observations that were acquired and are now being held at International Cooperator stations.

  7. Deafblindness, ontological security, and social recognition.

    PubMed

    Danermark, Berth D; Möller, Kerstin

    2008-11-01

    Trust, ontological security, and social recognition are discussed in relation to self-identity among people with acquired deafblindness. To date the phenomenon has not been elaborated in the context of deafblindness. When a person with deafblindness interacts with the social and material environment, the reliability, constancy, and predictability of his or her relations is crucial for maintaining or achieving ontological security or a general and fairly persistent feeling of well-being. When these relations fundamentally change, the impact on ontological security will be very negative. The construction of social recognition through the interaction between the self and others is embodied across three dimensions: at the individual level, at the legal systems level, and at the normative or value level. The relationship between trust and ontological security on the one hand and social recognition on the other hand is discussed. It is argued that these basic processes affecting personality development have to be identified and acknowledged in the interactions people with deafblindness experience. Some implications for the rehabilitation of people with acquired deafblindness are presented and illustrated.

  8. Learning reliable manipulation strategies without initial physical models

    NASA Technical Reports Server (NTRS)

    Christiansen, Alan D.; Mason, Matthew T.; Mitchell, Tom M.

    1990-01-01

    A description is given of a robot, possessing limited sensory and effectory capabilities but no initial model of the effects of its actions on the world, that acquires such a model through exploration, practice, and observation. By acquiring an increasingly correct model of its actions, it generates increasingly successful plans to achieve its goals. In an apparently nondeterministic world, achieving reliability requires the identification of reliable actions and a preference for using such actions. Furthermore, by selecting its training actions carefully, the robot can significantly improve its learning rate.

  9. Phenology of two interdependent traits in migratory birds in response to climate change.

    PubMed

    Kristensen, Nadiah Pardede; Johansson, Jacob; Ripa, Jörgen; Jonzén, Niclas

    2015-05-22

    In migratory birds, arrival date and hatching date are two key phenological markers that have responded to global warming. A body of knowledge exists relating these traits to evolutionary pressures. In this study, we formalize this knowledge into general mathematical assumptions, and use them in an ecoevolutionary model. In contrast to previous models, this study novelty accounts for both traits-arrival date and hatching date-and the interdependence between them, revealing when one, the other or both will respond to climate. For all models sharing the assumptions, the following phenological responses will occur. First, if the nestling-prey peak is late enough, hatching is synchronous with, and arrival date evolves independently of, prey phenology. Second, when resource availability constrains the length of the pre-laying period, hatching is adaptively asynchronous with prey phenology. Predictions for both traits compare well with empirical observations. In response to advancing prey phenology, arrival date may advance, remain unchanged, or even become delayed; the latter occurring when egg-laying resources are only available relatively late in the season. The model shows that asynchronous hatching and unresponsive arrival date are not sufficient evidence that phenological adaptation is constrained. The work provides a framework for exploring microevolution of interdependent phenological traits. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  10. Impact of cleaning and other interventions on the reduction of hospital-acquired Clostridium difficile infections in two hospitals in England assessed using a breakpoint model.

    PubMed

    Hughes, G J; Nickerson, E; Enoch, D A; Ahluwalia, J; Wilkinson, C; Ayers, R; Brown, N M

    2013-07-01

    Clostridium difficile infection remains a major challenge for hospitals. Although targeted infection control initiatives have been shown to be effective in reducing the incidence of hospital-acquired C. difficile infection, there is little evidence available to assess the effectiveness of specific interventions. To use statistical modelling to detect substantial reductions in the incidence of C. difficile from time series data from two hospitals in England, and relate these time points to infection control interventions. A statistical breakpoints model was fitted to likely hospital-acquired C. difficile infection incidence data from a teaching hospital (2002-2009) and a district general hospital (2005-2009) in England. Models with increasing complexity (i.e. increasing the number of breakpoints) were tested for an improved fit to the data. Partitions estimated from breakpoint models were tested for individual stability using statistical process control charts. Major infection control interventions from both hospitals during this time were grouped according to their primary target (antibiotics, cleaning, isolation, other) and mapped to the model-suggested breakpoints. For both hospitals, breakpoints coincided with enhancements to cleaning protocols. Statistical models enabled formal assessment of the impact of different interventions, and showed that enhancements to deep cleaning programmes are the interventions that have most likely led to substantial reductions in hospital-acquired C. difficile infections at the two hospitals studied. Copyright © 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  11. Modeling patterns of anatomical deformations in prostate patients undergoing radiation therapy with an endorectal balloon

    NASA Astrophysics Data System (ADS)

    Brion, Eliott; Richter, Christian; Macq, Benoit; Stützer, Kristin; Exner, Florian; Troost, Esther; Hölscher, Tobias; Bondar, Luiza

    2017-03-01

    External beam radiation therapy (EBRT) treats cancer by delivering daily fractions of radiation to a target volume. For prostate cancer, the target undergoes day-to-day variations in position, volume, and shape. For stereotactic photon and for proton EBRT, endorectal balloons (ERBs) can be used to limit variations. To date, patterns of non-rigid variations for patients with ERB have not been modeled. We extracted and modeled the patient-specific patterns of variations, using regularly acquired CT-images, non-rigid point cloud registration, and principal component analysis (PCA). For each patient, a non-rigid point-set registration method, called Coherent Point Drift, (CPD) was used to automatically generate landmark correspondences between all target shapes. To ensure accurate registrations, we tested and validated CPD by identifying parameter values leading to the smallest registration errors (surface matching error 0.13+/-0.09 mm). PCA demonstrated that 88+/-3.2% of the target motion could be explained using only 4 principal modes. The most dominant component of target motion is a squeezing and stretching in the anterior-posterior and superior-inferior directions. A PCA model of daily landmark displacements, generated using 6 to 10 CT-scans, could explain well the target motion for the CT-scans not included in the model (modeling error decreased from 1.83+/-0.8 mm for 6 CT-scans to 1.6+/-0.7 mm for 10 CT-scans). PCA modeling error was smaller than the naive approximation by the mean shape (approximation error 2.66+/-0.59 mm). Future work will investigate the use of the PCA-model to improve the accuracy of EBRT techniques that are highly susceptible to anatomical variations such as, proton therapy

  12. Remote sensing of intertidal morphological change in Morecambe Bay, U.K., between 1991 and 2007

    NASA Astrophysics Data System (ADS)

    Mason, D. C.; Scott, T. R.; Dance, S. L.

    2010-04-01

    Tidal Flats are important examples of extensive areas of natural environment that remain relatively unaffected by man. Monitoring of tidal flats is required for a variety of purposes. Remote sensing has become an established technique for the measurement of topography over tidal flats. A further requirement is to measure topographic changes in order to measure sediment budgets. To date there have been few attempts to make quantitative estimates of morphological change over tidal flat areas. This paper illustrates the use of remote sensing to measure quantitative and qualitative changes in the tidal flats of Morecambe Bay during the relatively long period 1991-2007. An understanding of the patterns of sediment transport within the Bay is of considerable interest for coastal management and defence purposes. Tidal asymmetry is considered to be the dominant cause of morphological change in the Bay, with the higher currents associated with the flood tide being the main agency moulding the channel system. Quantitative changes were measured by comparing a Digital Elevation Model (DEM) of the intertidal zone formed using the waterline technique applied to satellite Synthetic Aperture Radar (SAR) images from 1991-1994, to a second DEM constructed from airborne laser altimetry data acquired in 2005. Qualitative changes were studied using additional SAR images acquired since 2003. A significant movement of sediment from below Mean Sea Level (MSL) to above MSL was detected by comparing the two Digital Elevation Models, though the proportion of this change that could be ascribed to seasonal effects was not clear. Between 1991 and 2004 there was a migration of the Ulverston channel of the river Leven north-east by about 5 km, followed by the development of a straighter channel to the west, leaving the previous channel decoupled from the river. This is thought to be due to independent tidal and fluvial forcing mechanisms acting on the channel. The results demonstrate the effectiveness of remote sensing for measurement of long-term morphological change in tidal flat areas. An alternative use of waterlines as partial bathymetry for assimilation into a morphodynamic model of the coastal zone is also discussed.

  13. Prediction of Cancer Incidence and Mortality in Korea, 2018.

    PubMed

    Jung, Kyu-Won; Won, Young-Joo; Kong, Hyun-Joo; Lee, Eun Sook

    2018-04-01

    This study aimed to report on cancer incidence and mortality for the year 2018 to estimate Korea's current cancer burden. Cancer incidence data from 1999 to 2015 were obtained from the Korea National Cancer Incidence Database, and cancer mortality data from 1993 to 2016 were acquired from Statistics Korea. Cancer incidence and mortality were projected by fitting a linear regression model to observed age-specific cancer rates against observed years, then multiplying the projected age-specific rates by the age-specific population. The Joinpoint regression model was used to determine at which year the linear trend changed significantly, we only used the data of the latest trend. A total of 204,909 new cancer cases and 82,155 cancer deaths are expected to occur in Korea in 2018. The most common cancer sites were lung, followed by stomach, colorectal, breast and liver. These five cancers represent half of the overall burden of cancer in Korea. For mortality, the most common sites were lung cancer, followed by liver, colorectal, stomach and pancreas. The incidence rate of all cancer in Korea are estimated to decrease gradually, mainly due to decrease of thyroid cancer. These up-to-date estimates of the cancer burden in Korea could be an important resource for planning and evaluation of cancer-control programs.

  14. The good, the bad and the outliers: automated detection of errors and outliers from groundwater hydrographs

    NASA Astrophysics Data System (ADS)

    Peterson, Tim J.; Western, Andrew W.; Cheng, Xiang

    2018-03-01

    Suspicious groundwater-level observations are common and can arise for many reasons ranging from an unforeseen biophysical process to bore failure and data management errors. Unforeseen observations may provide valuable insights that challenge existing expectations and can be deemed outliers, while monitoring and data handling failures can be deemed errors, and, if ignored, may compromise trend analysis and groundwater model calibration. Ideally, outliers and errors should be identified but to date this has been a subjective process that is not reproducible and is inefficient. This paper presents an approach to objectively and efficiently identify multiple types of errors and outliers. The approach requires only the observed groundwater hydrograph, requires no particular consideration of the hydrogeology, the drivers (e.g. pumping) or the monitoring frequency, and is freely available in the HydroSight toolbox. Herein, the algorithms and time-series model are detailed and applied to four observation bores with varying dynamics. The detection of outliers was most reliable when the observation data were acquired quarterly or more frequently. Outlier detection where the groundwater-level variance is nonstationary or the absolute trend increases rapidly was more challenging, with the former likely to result in an under-estimation of the number of outliers and the latter an overestimation in the number of outliers.

  15. Endemic cryptosporidiosis and exposure to municipal tap water in persons with acquired immunodeficiency syndrome (AIDS): A case-control study

    PubMed Central

    Aragón, Tomás J; Novotny, Suzanne; Enanoria, Wayne; Vugia, Duc J; Khalakdina, Asheena; Katz, Mitchell H

    2003-01-01

    Background In persons with acquired immunodeficiency syndrome (AIDS), Cryptosporidium parvum causes a prolonged, severe diarrheal illness to which there is no effective treatment, and the risk of developing cryptosporidiosis from drinking tap water in non-outbreak settings remains uncertain. To test the hypothesis that drinking tap water was associated with developing cryptosporidiosis, we conducted a matched case-control study among persons with AIDS in San Francisco. Methods Among patients reported to the San Francisco AIDS Registry from May 1996 through September 1998, we compared patients who developed cryptosporidiosis to those who did not. Cases were individually matched to controls based on age, sex, race/ethnicity, CD4+ T lymphocyte count, date of CD4+ count, and date of case diagnosis. Population attributable fractions (PAFs) were calculated. Results The study consisted of 49 cases and 99 matched controls. In the multivariable analysis with adjustments for confounders, tap water consumption inside and outside the home at the highest exposure categories was associated with the occurrence of cryptosporidiosis (inside the home: odds ratio (OR), 6.76; 95% CI 1.37–33.5, and outside the home: OR 3.16; 95% CI 1.23–8.13). The PAF was 85%; that is, the proportion of cases of cryptosporidiosis in San Francisco AIDS patients attributable to tap water consumption could have been as high as 85%. Conclusions Although the results from this observational study cannot be considered definitive, until there is more data, we recommend persons with AIDS, especially those with compromised immune systems, consider avoiding tap water. PMID:12515584

  16. Endemic cryptosporidiosis and exposure to municipal tap water in persons with acquired immunodeficiency syndrome (AIDS): a case-control study.

    PubMed

    Aragón, Tomás J; Novotny, Suzanne; Enanoria, Wayne; Vugia, Duc J; Khalakdina, Asheena; Katz, Mitchell H

    2003-01-06

    In persons with acquired immunodeficiency syndrome (AIDS), Cryptosporidium parvum causes a prolonged, severe diarrheal illness to which there is no effective treatment, and the risk of developing cryptosporidiosis from drinking tap water in non-outbreak settings remains uncertain. To test the hypothesis that drinking tap water was associated with developing cryptosporidiosis, we conducted a matched case-control study among persons with AIDS in San Francisco. Among patients reported to the San Francisco AIDS Registry from May 1996 through September 1998, we compared patients who developed cryptosporidiosis to those who did not. Cases were individually matched to controls based on age, sex, race/ethnicity, CD4+ T lymphocyte count, date of CD4+ count, and date of case diagnosis. Population attributable fractions (PAFs) were calculated. The study consisted of 49 cases and 99 matched controls. In the multivariable analysis with adjustments for confounders, tap water consumption inside and outside the home at the highest exposure categories was associated with the occurrence of cryptosporidiosis (inside the home: odds ratio (OR), 6.76; 95% CI 1.37-33.5, and outside the home: OR 3.16; 95% CI 1.23-8.13). The PAF was 85%; that is, the proportion of cases of cryptosporidiosis in San Francisco AIDS patients attributable to tap water consumption could have been as high as 85%. Although the results from this observational study cannot be considered definitive, until there is more data, we recommend persons with AIDS, especially those with compromised immune systems, consider avoiding tap water.

  17. Pinpointing clusters of apparently sporadic cases of Legionnaires' disease.

    PubMed Central

    Bhopal, R. S.; Diggle, P.; Rowlingson, B.

    1992-01-01

    OBJECTIVES--To test the hypothesis that many non-outbreak cases of legionnaires' disease are not sporadic and to attempt to pinpoint cases clustering in space and time. DESIGN--Descriptive study of a case series, 1978-86. SETTING--15 health boards in Scotland. PATIENTS--203 probable cases of non-outbreak, non-travel, community acquired legionnaires' disease in patients resident in Scotland. MAIN MEASURES--Date of onset of disease and postcode and health board of residence of cases. RESULTS--Space-time clustering was present and numerous groups of cases were identified, all but two being newly recognised. Nine cases occurred during three months within two postcodes in Edinburgh, and an outbreak was probably missed. In several places cases occurred in one area over a prolonged period--for example, nine cases in postcode districts G11.5 and G12.8 in Glasgow during five years (estimated mean annual incidence of community acquired, non-outbreak, non-travel legionnaires' disease of 146 per million residents v 4.8 per million for Scotland). Statistical analysis showed that the space time clustering of cases in the Glasgow and Edinburgh areas was unusual (p = 0.036, p = 0.068 respectively). CONCLUSION--Future surveillance requires greater awareness that clusters can be overlooked; case searching whenever a case is identified; collection of complete information particularly of date of onset of the disease and address or postcode; ongoing analysis for space-time clustering; and an accurate yet workable definition of sporadic cases. Other researchers should re-examine their data on apparently sporadic infection. PMID:1586784

  18. Analysis and calibration of Safecasta data relative to the 2011 Fukushima Daiichi nuclear accident

    NASA Astrophysics Data System (ADS)

    Cervone, G.; Hultquist, C.

    2017-12-01

    Citizen-led movements producing scientific hazard data during disasters are increasingly common. After the Japanese earthquake-triggered tsunami in 2011, and the resulting radioactive releases at the damaged Fukushima Daiichi nuclear power plants, citizens monitored on-ground levels of radiation with innovative mobile devices built from off-the-shelf components. To date, the citizen-led Safecast project has recorded 50 million radiation measurements world- wide, with the majority of these measurements from Japan. A robust methodology is presented to calibrate contributed Safecast radiation measurements acquired between 2011 and 2016 in the Fukushima prefecture of Japan. The Safecast data are calibrated using official observations acquired by the U.S. Department of Energy at the time of the 2011 Fukushima Daiichi power plant nuclear accident. The methodology performs a series of interpolations between the official and contributed datasets at specific time windows and at corresponding spatial locations. The coefficients found are aggregated and interpolated using cubic and linear methods to generate time dependent calibration function. Normal background radiation, decay rates and missing values are taken into account during the analysis. Results show that the official Safecast static transformation function overestimates the official measurements because it fails to capture the presence of two different Cesium isotopes and their changing ratio with time. The new time dependent calibration function takes into account the presence of different Cesium isotopes, and minimizes the error between official and contributed data. This time dependent Safecast calibration function is necessary until 2030, after which date the error caused by the isotopes ratio will become negligible.

  19. A first assessment of Sentinel-3 SAR altimetry over ice sheets

    NASA Astrophysics Data System (ADS)

    McMillan, M.; Muir, A. S.; Shepherd, A.

    2017-12-01

    The first Sentinel-3 satellite was launched in 2016 and carries onboard a Ku-band Synthetic Aperture Radar (SAR) altimeter. With coverage up to a latitude of 81.5 degrees and a repeat period of 27 days, it offers the opportunity to measure surface topography and elevation change across much of the Antarctic and Greenland Ice Sheets, therefore continuing the existing 25 year radar altimeter record. The global operation of Sentinel-3 in SAR mode differs from all past Ku-band instruments; for the first time SAR measurements are routinely acquired across the interiors of the ice sheets; however unlike CryoSat-2 it does not carry an interferometer to aid signal retrieval in regions of complex coastal terrain. In view of these differences and the novel characteristics of the Sentinel-3 system, assessments of the performance of the instrument are required, to evaluate the satellite's utility for monitoring Earth's Polar regions. Here, we analyse data acquired during the first year of routine operations, to assess the performance of the Sentinel-3 SAR altimeter to date. We focus both on inland ice sheet regions, where Sentinel-3 provides the first operational SAR altimeter measurements, and also on coastal areas with more complex topography. We investigate SAR waveforms and retrieved elevations in both regions, and through comparison to measurements from earlier missions examine the impact of the different modes of operation. We also conduct a high level evaluation of the data, by comparing it to reference airborne altimetry, to provide an assessment of Sentinel-3 performance to date over ice sheets.

  20. An Empirical Verification of a-priori Learning Models on Mailing Archives in the Context of Online Learning Activities of Participants in Free\\Libre Open Source Software (FLOSS) Communities

    ERIC Educational Resources Information Center

    Mukala, Patrick; Cerone, Antonio; Turini, Franco

    2017-01-01

    Free\\Libre Open Source Software (FLOSS) environments are increasingly dubbed as learning environments where practical software engineering skills can be acquired. Numerous studies have extensively investigated how knowledge is acquired in these environments through a collaborative learning model that define a learning process. Such a learning…

  1. Signal template generation from acquired mammographic images for the non-prewhitening model observer with eye-filter

    NASA Astrophysics Data System (ADS)

    Balta, Christiana; Bouwman, Ramona W.; Sechopoulos, Ioannis; Broeders, Mireille J. M.; Karssemeijer, Nico; van Engen, Ruben E.; Veldkamp, Wouter J. H.

    2017-03-01

    Model observers (MOs) are being investigated for image quality assessment in full-field digital mammography (FFDM). Signal templates for the non-prewhitening MO with eye filter (NPWE) were formed using acquired FFDM images. A signal template was generated from acquired images by averaging multiple exposures resulting in a low noise signal template. Noise elimination while preserving the signal was investigated and a methodology which results in a noise-free template is proposed. In order to deal with signal location uncertainty, template shifting was implemented. The procedure to generate the template was evaluated on images of an anthropomorphic breast phantom containing microcalcification-related signals. Optimal reduction of the background noise was achieved without changing the signal. Based on a validation study in simulated images, the difference (bias) in MO performance from the ground truth signal was calculated and found to be <1%. As template generation is a building stone of the entire image quality assessment framework, the proposed method to construct templates from acquired images facilitates the use of the NPWE MO in acquired images.

  2. Time Series Remote Sensing in Monitoring the Spatio-Temporal Dynamics of Plant Invasions: A Study of Invasive Saltcedar (Tamarix Spp.)

    NASA Astrophysics Data System (ADS)

    Diao, Chunyuan

    In today's big data era, the increasing availability of satellite and airborne platforms at various spatial and temporal scales creates unprecedented opportunities to understand the complex and dynamic systems (e.g., plant invasion). Time series remote sensing is becoming more and more important to monitor the earth system dynamics and interactions. To date, most of the time series remote sensing studies have been conducted with the images acquired at coarse spatial scale, due to their relatively high temporal resolution. The construction of time series at fine spatial scale, however, is limited to few or discrete images acquired within or across years. The objective of this research is to advance the time series remote sensing at fine spatial scale, particularly to shift from discrete time series remote sensing to continuous time series remote sensing. The objective will be achieved through the following aims: 1) Advance intra-annual time series remote sensing under the pure-pixel assumption; 2) Advance intra-annual time series remote sensing under the mixed-pixel assumption; 3) Advance inter-annual time series remote sensing in monitoring the land surface dynamics; and 4) Advance the species distribution model with time series remote sensing. Taking invasive saltcedar as an example, four methods (i.e., phenological time series remote sensing model, temporal partial unmixing method, multiyear spectral angle clustering model, and time series remote sensing-based spatially explicit species distribution model) were developed to achieve the objectives. Results indicated that the phenological time series remote sensing model could effectively map saltcedar distributions through characterizing the seasonal phenological dynamics of plant species throughout the year. The proposed temporal partial unmixing method, compared to conventional unmixing methods, could more accurately estimate saltcedar abundance within a pixel by exploiting the adequate temporal signatures of saltcedar. The multiyear spectral angle clustering model could guide the selection of the most representative remotely sensed image for repetitive saltcedar mapping over space and time. Through incorporating spatial autocorrelation, the species distribution model developed in the study could identify the suitable habitats of saltcedar at a fine spatial scale and locate appropriate areas at high risk of saltcedar infestation. Among 10 environmental variables, the distance to the river and the phenological attributes summarized by the time series remote sensing were regarded as the most important. These methods developed in the study provide new perspectives on how the continuous time series can be leveraged under various conditions to investigate the plant invasion dynamics.

  3. Advances in Medical Analytics Solutions for Autonomous Medical Operations on Long-Duration Missions

    NASA Technical Reports Server (NTRS)

    Thompson, David E.; Lindsey, Antonia Edward

    2017-01-01

    A review will be presented on the progress made under STMDGame Changing Development Program Funding towards the development of a Medical Decision Support System for augmenting crew capabilities during long-duration missions, such as Mars Transit. To create an MDSS, initial work requires acquiring images and developing models that analyze and assess the features in such medical biosensor images that support medical assessment of pathologies. For FY17, the project has focused on ultrasound images towards cardiac pathologies: namely, evaluation and assessment of pericardial effusion identification and discrimination from related pneumothorax and even bladder-induced infections that cause inflammation around the heart. This identification is substantially changed due to uncertainty due to conditions of fluid behavior under space-microgravity. This talk will present and discuss the work-to-date in this Project, recognizing conditions under which various machine learning technologies, deep-learning via convolutional neural nets, and statistical learning methods for feature identification and classification can be employed and conditioned to graphical format in preparation for attachment to an inference engine that eventually creates decision support recommendations to remote crew in a triage setting.

  4. Sentinel Chicken Seroconversions Track Tangential Transmission of West Nile Virus to Humans in the Greater Los Angeles Area of California

    PubMed Central

    Kwan, Jennifer L.; Kluh, Susanne; Madon, Minoo B.; Nguyen, Danh V.; Barker, Christopher M.; Reisen, William K.

    2010-01-01

    In Los Angeles, California, West Nile virus (WNV) has followed a pattern of emergence, amplification, subsidence, and resurgence. A time series cross-correlation analysis of human case counts and sentinel chicken seroconversions revealed temporal concordance indicating that chicken seroconversions tracked tangential transmission of WNV from the basic passeriform-Culex amplification cycle to humans rather than antecedent enzootic amplification. Sentinel seroconversions provided the location and time of transmission as opposed to human cases, which frequently were reported late and were assumed to be acquired 2–14 days before disease onset at their residence. Cox models revealed that warming degree-days were associated with the increased risk of seroconversion, whereas elevated herd immunity in peridomestic birds dampened seroconversion risk. Spatially, surveillance data collected within a 5 km radius of flock locations 15–28 days before the bleed date were most predictive of a seroconversion. In urban Los Angeles, sentinel chicken seroconversions could be used as an outcome measure in decision support for emergency intervention. PMID:21036853

  5. Photodissociation of quantum state-selected diatomic molecules yields new insight into ultracold chemistry

    NASA Astrophysics Data System (ADS)

    McDonald, Mickey; McGuyer, Bart H.; Lee, Chih-Hsi; Apfelbeck, Florian; Zelevinsky, Tanya

    2016-05-01

    When a molecule is subjected to a sufficiently energetic photon it can break apart into fragments through a process called ``photodissociation''. For over 70 years this simple chemical reaction has served as a vital experimental tool for acquiring information about molecular structure, since the character of the photodissociative transition can be inferred by measuring the 3D photofragment angular distribution (PAD). While theoretical understanding of this process has gradually evolved from classical considerations to a fully quantum approach, experiments to date have not yet revealed the full quantum nature of this process. In my talk I will describe recent experiments involving the photodissociation of ultracold, optical lattice-trapped, and fully quantum state-resolved 88Sr2 molecules. Optical absorption images of the PADs produced in these experiments reveal features which are inherently quantum mechanical in nature, such as matter-wave interference between output channels, and are sensitive to the quantum statistics of the molecular wavefunctions. The results of these experiments cannot be predicted using quasiclassical methods. Instead, we describe our results with a fully quantum mechanical model yielding new intuition about ultracold chemistry.

  6. Design of peptide mimetics to block pro-inflammatory functions of HA fragments.

    PubMed

    Hauser-Kawaguchi, Alexandra; Luyt, Leonard G; Turley, Eva

    2018-01-31

    Hyaluronan is a simple extracellular matrix polysaccharide that actively regulates inflammation in tissue repair and disease processes. The native HA polymer, which is large (>500 kDa), contributes to the maintenance of homeostasis. In remodeling and diseased tissues, polymer size is strikingly polydisperse, ranging from <10 kDa to >500 kDa. In a diseased or stressed tissue context, both smaller HA fragments and high molecular weight HA polymers can acquire pro-inflammatory functions, which result in the activation of multiple receptors, triggering pro-inflammatory signaling to diverse stimuli. Peptide mimics that bind and scavenge HA fragments have been developed, which show efficacy in animal models of inflammation. These studies indicate both that HA fragments are key to driving inflammation and that scavenging these is a viable therapeutic approach to blunting inflammation in disease processes. This mini-review summarizes the peptide-based methods that have been reported to date for blocking HA signaling events as an anti-inflammatory therapeutic approach. Copyright © 2017 International Society of Matrix Biology. Published by Elsevier B.V. All rights reserved.

  7. TH-CD-207A-10: Using the Gamma Index to Flag Changes in Anatomy During Radiation Therapy of Head and Neck Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schaly, B; Battista, J; Department of Medical Biophysics, Western University, London, Ontario Canada

    Purpose: This article presents a fast algorithm for comparing 3-D anatomy from Cone-Beam CT (CBCT) imaging using the gamma comparison index and to demonstrate how this can be used to flag patients for possible re-planning of treatment. Methods: CBCT scans acquired on a Varian linear accelerator during treatment were used as input to the gamma comparator using thresholds of 5 mm distance to agreement and 30 Hounsfield Unit CT number difference. The fraction 1 CBCT study was initially used as the reference. Should there be a re-plan during treatment, the reference resets to the CBCT study acquired on the daymore » 1 of the re-plan. Histograms of failing pixels (γ > 1) were generated from each 3-D gamma map. An indicator of anatomy congruence, the match quality parameter (MQP), was derived from failed pixel histograms using the 90th percentile gamma value. The MQP was plotted versus fraction number and related to actual repeat computed tomography (re-CT) order dates as decided by a radiation oncologist. From this, decision criteria were derived for the algorithm to “trigger” re-CT consideration and predictive power was scored using receiver-operator characteristic (ROC) analysis. Results: The MQP plot generally showed that the on-line match from CBCT image guidance deteriorated as the treatment progressed due to weight loss and tumor regression. The optimized MQP criteria for triggering re-CT consideration demonstrated high sensitivity and specificity, consistent with actual re-CT order dates within ± 3 fractions. Out of 20 patients that were actually re-planned, the algorithm failed to trigger a re-CT recommendation only twice and this was caused by CBCT ring artifacts. Conclusion: We have demonstrated that gamma comparisons can be used to evaluate CBCT-acquired anatomy pairs and, from this, an algorithm can be “trained” to flag patients for possible re-planning in a manner consistent with local radiation oncology practice.« less

  8. A Tale of Two Comets: ISON

    NASA Image and Video Library

    2013-11-26

    Release Date: November 25, 2013 MESSENGER image of comet C/2012 S1 (ISON) during its closest approach to Mercury. At that time, ISON was approximately 22.5 million miles (36.2 million kilometers) from MESSENGER and 42.1 million miles (67.8 million kilometers) from the Sun. The image is 7° by 4.7° in size and has been slightly magnified and smoothed to enhance the faint tail of the comet. The tail was oriented at an angle to MESSENGER at the time and is foreshortened in this image; however, some faint structure can still be seen. MESSENGER's cameras have been acquiring targeted observations (watch an animation here) of Encke since October 28 and ISON since October 26, although the first faint detections didn't come until early November. During the closest approach of each comet to Mercury, the Mercury Atmospheric and Surface Composition Spectrometer (MASCS) and X-Ray Spectrometer (XRS) instruments also targeted the comets. Observations of ISON conclude on November 26, when the comet passes too close to the Sun, but MESSENGER will continue to monitor Encke with both the imagers and spectrometers through early December. Read this mission news story for more details. The MESSENGER spacecraft is the first ever to orbit the planet Mercury, and the spacecraft's seven scientific instruments and radio science investigation are unraveling the history and evolution of the Solar System's innermost planet. During the first two years of orbital operations, MESSENGER acquired over 150,000 images and extensive other data sets. MESSENGER is capable of continuing orbital operations until early 2015. Date acquired: 01:54:30 UTC on November 20, 2013 Instrument: Wide Angle Camera (WAC) of the Mercury Dual Imaging System (MDIS) Credit: NASA/Johns Hopkins University Applied Physics Laboratory/Carnegie Institution of Washington/Southwest Research Institute NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  9. Beyond restoration to transformation: positive outcomes in the rehabilitation of acquired brain injury.

    PubMed

    McGrath, Joanna

    2004-11-01

    This paper compares the situation of the person with acquired brain injury to that of the people of Israel in the sixth century BCE (before the current era) during the period of exile in Babylon. Both situations are characterized by traumatic multiple losses, and a struggle to regain a sense of identity: personal, national or spiritual. Evidence from the literature on both brain injury rehabilitation and from the Hebrew Scriptures indicates that models of restoration of function and transformation of suffering have been applied to both situations. The relative strengths and weaknesses of these models are considered, and it is argued that models of transformation of suffering have much to offer, especially in the longer term psychotherapeutic rehabilitation of people with acquired brain injury, when restoration of function has reached its limits.

  10. Glacial-Geomorphological Evidence for Past Ice Cover in the Western Amundsen Sea Embayment of Antarctica

    NASA Astrophysics Data System (ADS)

    Roberts, S. J.; Johnson, J.; Ireland, L.; Rood, D. H.; Schaefer, J. M.; Whitehouse, P. L.; Pollard, D.

    2016-12-01

    Reliable model predictions of the future evolution of the West Antarctic Ice Sheet in the Amundsen Sea Embayment of Antarctica are currently hindered by a lack of data on the regional thinning history, particularly to the west of Thwaites Glacier. Our project will fill this critical gap by acquiring glacial-geological data, in particular, a high density of cosmogenic exposure ages that record ice sheet changes in the western Amundsen Sea Embayment over the past 20,000 years. In 2015/6, during the first of two field seasons in the region, we collected glacial-geomorphological evidence and cosmogenic surface exposure dating samples to constrain past ice cover of nunataks around Mt Murphy, which are adjacent to the Pope Glacier. The presence of abundant rounded granite and gneiss cobbles perched on bedrock ridges and terraces up to 885 m asl, as well as extensive striated bedrock above this height, indicate that ice was much thicker in the past. We also present preliminary results from a novel study on Turtle Rock, a key site for understanding past fluctuations of Pope Glacier. We used an unmanned aerial vehicle (UAV) to map the geomorphology of selected areas in greater detail than is currently possible from high-resolution satellite imagery, and ground-truthed the data by measuring the size, orientation and lithological composition of erratic cobbles and boulders. Combined with surface exposure dating, we will use these datasets to determine whether there were multiple phases of ice overriding, and the timing of thinning of Pope Glacier since the Last Glacial Maximum.

  11. A degree-day model initiated by pheromone trap captures for managing pecan nut casebearer (Lepidoptera: Pyralidae) in pecans.

    PubMed

    Knutson, Allen E; Muegge, Mark A

    2010-06-01

    Field observations from pecan, Carya illinoinensis (Wangenh.) Koch, orchards in Texas were used to develop and validate a degree-day model of cumulative proportional adult flight and oviposition and date of first observed nut entry by larvae of the first summer generation of the pecan nut casebearer, Acrobasis nuxvorella Nuenzig (Lepidoptera: Pyralidae). The model was initiated on the date of first sustained capture of adults in pheromone traps. Mean daily maximum and minimum temperatures were used to determine the sum of degree-days from onset to 99% moth flight and oviposition and the date on which first summer generation larvae were first observed penetrating pecan nuts. Cumulative proportional oviposition (y) was described by a modified Gompertz equation, y = 106.05 x exp(-(exp(3.11 - 0.00669 x (x - 1), with x = cumulative degree-days at a base temperature of 3.33 degrees C. Cumulative proportional moth flight (y) was modeled as y = 102.62 x exp(- (exp(1.49 - 0.00571 x (x - 1). Model prediction error for dates of 10, 25, 50, 75, and 90% cumulative oviposition was 1.3 d and 83% of the predicted dates were within +/- 2 d of the observed event. Prediction error for date of first observed nut entry was 2.2 d and 77% of model predictions were within +/- 2 d of the observed event. The model provides ample lead time for producers to implement orchard scouting to assess pecan nut casebearer infestations and to apply an insecticide if needed to prevent economic loss.

  12. Experimental flutter boundaries with unsteady pressure distributions for the NACA 0012 Benchmark Model

    NASA Technical Reports Server (NTRS)

    Rivera, Jose A., Jr.; Dansberry, Bryan E.; Farmer, Moses G.; Eckstrom, Clinton V.; Seidel, David A.; Bennett, Robert M.

    1991-01-01

    The Structural Dynamics Div. at NASA-Langley has started a wind tunnel activity referred to as the Benchmark Models Program. The objective is to acquire test data that will be useful for developing and evaluating aeroelastic type Computational Fluid Dynamics codes currently in use or under development. The progress is described which was achieved in testing the first model in the Benchmark Models Program. Experimental flutter boundaries are presented for a rigid semispan model (NACA 0012 airfoil section) mounted on a flexible mount system. Also, steady and unsteady pressure measurements taken at the flutter condition are presented. The pressure data were acquired over the entire model chord located at the 60 pct. span station.

  13. Anaglyph, Yucatan Peninsula, Mexico

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This anaglyph (stereoscopic view) of Mexico's Yucatan Peninsula was generated entirely from Shuttle Radar Topography Mission (SRTM) data, and shows a subtle but distinctive indication of the Chicxulub impact crater. Most scientists now agree that this impact was the cause of the Cretatious-Tertiary extinction, the event 65 million years ago that marked the demise of the dinosaurs as well as the majority of life then on Earth. The crater's rim is marked by a shallow semicircular depression arcing about an offshore center point in the upper left of the picture. (The arcing depression is just above the blue line, when viewed with the naked eye.) This depression, or trough, only about 3 to 5 meters (10 - 15 feet) deep and about 5 kilometers (3 miles) wide, was likely caused by collapse of limestone caverns preferentially above the crater rim, resulting in an arcing chain of sinkholes. The limestone that covers most of the Yucatan Peninsula post-dates the impact crater. However, the crater pattern apparently controls the subsidence pattern just enough to show through.

    This anaglyph was created by deriving a shaded relief image from the SRTM data, draping it back over the SRTM elevation model, and then generating two differing perspectives, one for each eye. Illumination is from the north (top). When viewed through special glasses, the anaglyph is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter. The total relief (range of elevations) across this entire image is less than 300 meters (1000 feet).

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect 3-D measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter (approximately 200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, Calif., for NASA's Earth Science Enterprise, Washington, D.C.

    Size: 465 by 334 kilometers (288 by 207 miles) Location: 20 degrees North latitude, 89 degrees West longitude Orientation: North toward the top Image Data: Shaded SRTM elevation model Original Data Resolution: SRTM 1 arcsecond (about 30 meters or 98 feet) Date Acquired: February 2000

  14. In Charon's Shadow: Analysis of the UV Solar Occultation from New Horizons

    NASA Astrophysics Data System (ADS)

    Kammer, Joshua A.; Stern, S. A.; Weaver, H. A.; Young, L. A.; Ennico, K. A.; Olkin, C. B.; Gladstone, G. R.; Summers, M. E.; Greathouse, T. K.; Retherford, K. D.; Versteeg, M. H.; Parker, J. W.; Steffl, A. J.; Schindhelm, E.; Strobel, D. F.; Linscott, I. R.; Hinson, D. P.; Tyler, G. L.; Woods, W. W.

    2015-11-01

    Observations of Charon, Pluto's largest moon, have so far yielded no evidence for a substantial atmosphere. However, during the flyby of New Horizons through the Pluto-Charon system, the Alice ultraviolet spectrograph successfully acquired the most sensitive measurements to date during an occultation of the sun as New Horizons passed through Charon's shadow. These observations include wavelength coverage in the extreme- and far-ultraviolet (EUV and FUV) from 52 nm to 187 nm. We will present these results from Alice, and discuss their implications for an atmosphere on Charon.This work was supported by NASA's New Horizons project.

  15. The sanctuary of Punta Stilo at Kaulonia-Monasterace (Rc, Italy): preliminary results of the close range photogrammetric surveys 2012-2013

    NASA Astrophysics Data System (ADS)

    Taccola, E.; Parra, M. C.; Ampolo, C.

    2014-06-01

    During the 2012-2013 excavations at the Sanctuary of Punta Stilo at Kaulonia, carried out by the University of Pisa and the Scuola Normale Superiore of Pisa, close range aerial and terrestrial photogrammetric surveys were tested for the first time. The aim of the test was to verify the accuracy of the site planimetry currently used, dating back also to a century ago. The 3D data obtained have allowed new data to be acquired for correcting and updating the mapping of the site.

  16. Detection of aspen-conifer forest mixes from LANDSAT digital data. [Utah-Idaho Bear River Range

    NASA Technical Reports Server (NTRS)

    Jaynes, R. A.; Merola, J. A.

    1982-01-01

    Aspen, conifer and mixed aspen/conifer forests were mapped for a 15-quadrangle study area in the Utah-Idaho Bear River Range using LANDSAT multispectral scanner data. Digital classification and statistical analysis of LANDSAT data allowed the identification of six groups of signatures which reflect different types of aspen/conifer forest mixing. Photo interpretations of the print symbols suggest that such classes are indicative of mid to late seral aspen forests. Digital print map overlays and acreage calculations were prepared for the study area quadrangles. Further field verification is needed to acquire additional information about the nature of the forests. Single date LANDSAT analysis should be a cost effective means to index aspen forests which are at least in the mid seral phase of conifer invasion. Since aspen canopies tend to obscure understory conifers for early seral forests, a second date analysis, using data taken when aspens are leafless, could provide information about early seral aspen forests.

  17. Randomized Controlled Trial for Behavioral Smoking and Weight Control Treatment: Effect of Concurrent versus Sequential Intervention

    PubMed Central

    Spring, Bonnie; Doran, Neal; Pagoto, Sherry; Schneider, Kristin; Pingitore, Regina; Hedeker, Don

    2014-01-01

    Prospects for changing multiple health behaviors conjointly remain controversial. We compared effects on tobacco abstinence and weight gain of adding diet and exercise concurrently or after smoking treatment. Female regular smokers (n=315) randomized to 3 conditions received 16 weeks of behavioral smoking treatment, quit at week 5, and were followed for 9 months after the quit date. Weight management was added to the first 8 weeks for Early Diet (ED), the final 8 weeks for Late Diet (LD), and omitted for Control. Both Diet groups tended to show greater bio-verified abstinence than Control although differences were nonsignificant. Compared to Control, ED initially suppressed weight gain but lost that effect over time, whereas LD initially lacked but gradually acquired a weight suppression effect that stabilized [p = .004]. Behavioral weight control did not undermine smoking cessation and slowed the rate of weight gain when initiated after the smoking quit date, supporting a sequential approach to multiple behavior change. PMID:15482037

  18. a Comparison Study of Different Kernel Functions for Svm-Based Classification of Multi-Temporal Polarimetry SAR Data

    NASA Astrophysics Data System (ADS)

    Yekkehkhany, B.; Safari, A.; Homayouni, S.; Hasanlou, M.

    2014-10-01

    In this paper, a framework is developed based on Support Vector Machines (SVM) for crop classification using polarimetric features extracted from multi-temporal Synthetic Aperture Radar (SAR) imageries. The multi-temporal integration of data not only improves the overall retrieval accuracy but also provides more reliable estimates with respect to single-date data. Several kernel functions are employed and compared in this study for mapping the input space to higher Hilbert dimension space. These kernel functions include linear, polynomials and Radial Based Function (RBF). The method is applied to several UAVSAR L-band SAR images acquired over an agricultural area near Winnipeg, Manitoba, Canada. In this research, the temporal alpha features of H/A/α decomposition method are used in classification. The experimental tests show an SVM classifier with RBF kernel for three dates of data increases the Overall Accuracy (OA) to up to 3% in comparison to using linear kernel function, and up to 1% in comparison to a 3rd degree polynomial kernel function.

  19. Healed Depressed Parasagittal Skull Fractures-A Feature of Archaic Australian Aboriginal Remains.

    PubMed

    Walshe, Keryn; Brophy, Brian; Cornish, Brian; Byard, Roger W

    2016-11-01

    The skeletal remains of eight Australian Aboriginals with healed depressed skull fractures were examined. Male:female ratio 5:3; age range 20-60 yrs. Burial dates by 14 C dating in three cases were 500 years BP (n = 2) and 1300 BP. There were 13 healed depressed skull fractures manifested by shallow indentations of cortical bone and thinning of diploe, with no significant disturbance of the inner skull tables. Nine (69%) were located within 35 mm of the sagittal suture/midline. These lesions represent another acquired feature that might be helpful in suggesting that a skull is from a tribal Aboriginal individual and may be particularly useful if the remains are represented by only fragments of calvarium. While obviously not a finding specific to this population, these healed injuries would be consistent with the possible results of certain types of conflict behavior reported in traditional Aboriginal groups that involved formalized inflicted blunt head trauma. © 2016 American Academy of Forensic Sciences.

  20. Perspective View, New York State, Lake Ontario to Long Island

    NASA Technical Reports Server (NTRS)

    2000-01-01

    From Lake Ontario and the St. Lawrence River (at the bottom of the image) and extending to Long Island (at the top), this perspective view shows the varied topography of eastern New York State and parts of Massachusetts, Connecticut, Pennsylvania, New Jersey and Rhode Island. The high 'bumpy' area in the left foreground is the southern and western Adirondack Mountains, a deeply eroded landscape that includes the oldest rocks in the eastern United States. On the right side are the Catskill Mountains, a part of the Appalachian Mountain chain, where river erosion has produced an intricate pattern of valleys. Between the Adirondacks and Catskills, A wide valley contains the Mohawk River and the Erie Canal. To the northwest (lower right) of the Catskills are the Finger Lakes of central New York . They were carved by the vast glacier that covered this entire area as recently as 18,000 years ago. The Hudson River runs along a straight valley from left center (near Glens Falls), widening out as it approaches New York City at the upper right on the image. The Connecticut River valley has a similar north-south trend further to the east (across the upper left corner of the image). The Berkshire Hills are between the Hudson and Connecticut valleys.

    This image was generated using a single swath of data acquired in 68 seconds by SRTM and an enhanced false-color mosaic of images from the Landsat 5 satellite. Lush vegetation appears green, water appears dark blue, and cities are generally light blue. White clouds occur in the upper left and lower left. Topographic shading in the image was enhanced with false shading derived from the elevation model. Topographic expression is exaggerated 5X.

    Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Earth Science Enterprise, Washington, DC.

    Size: 220 by 510 kilometers (135 by 315 miles) Location: 43 deg. North lat., 75 deg. West lon. Orientation: View southeast Colors: Landsat bands 2,4,7 in blue, green, and red Date Acquired: February 13, 2000 (SRTM); Various Dates (Landsat Mosaic) Image: NASA/JPL/NIMA

  1. Perspective View, New York State, Long Island to Lake Ontario

    NASA Technical Reports Server (NTRS)

    2000-01-01

    From Lake Ontario and the St. Lawrence River (at the top of the image) and extending to Long Island (at the bottom), this perspective view shows the varied topography of eastern New York State and parts of Massachusetts, Connecticut, Pennsylvania, New Jersey and Rhode Island. The high'bumpy' area in the upper right is the southern and western Adirondack Mountains, a deeply eroded landscape that includes the oldest rocks in the eastern United States. On the left side are the Catskill Mountains, a part of the Appalachian Mountain chain, where river erosion has produced an intricate pattern of valleys. Between the Adirondacks and Catskills, a wide valley contains the Mohawk River and the Erie Canal. To the northwest (upper left) of the Catskills are several long, narrow lakes, some of the Finger Lakes of central New York that were carved by the vast glacier that covered this entire area as recently as 18,000 years ago. The Hudson River runs along a straight valley from right center (near Glens Falls), widening out as it approaches New York City at the lower left on the image. The Connecticut River valley has a similar north-south trend further to the east (across the lower right corner of the image). The Berkshire Hills are between the Hudson and Connecticut valleys.

    This image was generated using a single swath of data acquired in 68 seconds by SRTM and an enhanced false-color mosaic of images from the Landsat 5 satellite. Lush vegetation appears green, water appears dark blue, and cities are generally light blue. White clouds occur in the upper right and lower right. Topographic shading in the image was enhanced with false shading derived from the elevation model. Topographic expression is exaggerated 5X.

    Elevation data used in this image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11,2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Earth Science Enterprise,Washington, DC.

    Size: 220 by 510 kilometers (135 by 315 miles) Location: 43 deg. North lat., 75 deg. West lon. Orientation: View northwest Colors: Landsat bands 2, 4, 7 in blue, green, and red Date Acquired: February 13, 2000 (SRTM); Various Dates (Landsat Mosaic)

  2. Is methicillin-resistant Staphylococcus aureus an emerging community pathogen? A review of the literature

    PubMed Central

    Gardam, Michael A

    2000-01-01

    OBJECTIVES: To discuss the historical epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and review the literature suggesting that MRSA has become a community pathogen. DATA SOURCES: A search of the MEDLINE database was performed, encompassing all English or French language citations from 1966 to 1999 and containing the subjects and/or text words: 'Staphylococcus aureus', 'methicillin resistance', 'endocarditis', 'cellulites', 'pneumonia' and 'community-acquired'. Articles published in other languages that provided English or French abstracts were included. All relevant references cited in articles obtained from the MEDLINE database and book chapters were also included. DATA EXTRACTION: All articles obtained from the above sources were examined and were included in the review if a laboratory or epidemiological study of community-acquired MRSA was presented. DATA SYNTHESIS AND CONCLUSIONS: MRSA has emerged over the past 30 years to become a worldwide nosocomial pathogen and has recently been reported as a cause of community-acquired infections. The changing epidemiology of MRSA is likely because of two mechanisms: the movement of nosocomial MRSA strains into the community and the de novo appearance of community strains resulting from the transfer of genetic material from methicillin-resistant Gram-positive organisms to sensitive S aureus strains. The emergence of MRSA as a community pathogen has occurred at a slower rate than it did for penicillin-resistant S aureus (PRSA) in the 1950s and 1960s, possibly because the mechanism of methicillin resistance does not exhibit the same ease of transferability as that of penicillin resistance. Four case reports, seven case series, 10 case-control studies and two cohort studies on community-acquired MRSA were analyzed. Determining whether these reports involve new community-acquired strains rather than previously acquired nosocomial strains can be problematic. It appears, however, that MRSA strains of both nosocomial and community origin are now endemic in certain communities in different parts of the world. Few surveillance studies of nonhospitalized patient populations have been performed to date; thus, the true prevalence of MRSA in the community at large is essentially unknown, although it appears to be low. At present, the empirical treatment of community-acquired S aureus infections with a beta-lactamase-stable beta-lactam antibiotic is appropriate for most populations. However, empirical vancomycin therapy for serious S aureus infections should be strongly considered for patients with significant risk factors for previously-acquired nosocomial MRSA or for patients belonging to outpatient populations with a proven high prevalence of MRSA. Increasing vancomycin use will likely have a significant impact on the development of resistance in Gram-positive organisms. PMID:18159291

  3. Imaging During MESSENGER's Second Flyby of Mercury

    NASA Astrophysics Data System (ADS)

    Chabot, N. L.; Prockter, L. M.; Murchie, S. L.; Robinson, M. S.; Laslo, N. R.; Kang, H. K.; Hawkins, S. E.; Vaughan, R. M.; Head, J. W.; Solomon, S. C.; MESSENGER Team

    2008-12-01

    During MESSENGER's second flyby of Mercury on October 6, 2008, the Mercury Dual Imaging System (MDIS) will acquire 1287 images. The images will include coverage of about 30% of Mercury's surface not previously seen by spacecraft. A portion of the newly imaged terrain will be viewed during the inbound portion of the flyby. On the outbound leg, MDIS will image additional previously unseen terrain as well as regions imaged under different illumination geometry by Mariner 10. These new images, when combined with images from Mariner 10 and from MESSENGER's first Mercury flyby, will enable the first regional- resolution global view of Mercury constituting a combined total coverage of about 96% of the planet's surface. MDIS consists of both a Wide Angle Camera (WAC) and a Narrow Angle Camera (NAC). During MESSENGER's second Mercury flyby, the following imaging activities are planned: about 86 minutes before the spacecraft's closest pass by the planet, the WAC will acquire images through 11 different narrow-band color filters of the approaching crescent planet at a resolution of about 5 km/pixel. At slightly less than 1 hour to closest approach, the NAC will acquire a 4-column x 11-row mosaic with an approximate resolution of 450 m/pixel. At 8 minutes after closest approach, the WAC will obtain the highest-resolution multispectral images to date of Mercury's surface, imaging a portion of the surface through 11 color filters at resolutions of about 250-600 m/pixel. A strip of high-resolution NAC images, with a resolution of approximately 100 m/pixel, will follow these WAC observations. The NAC will next acquire a 15-column x 13- row high-resolution mosaic of the northern hemisphere of the departing planet, beginning approximately 21 minutes after closest approach, with resolutions of 140-300 m/pixel; this mosaic will fill a large gore in the Mariner 10 data. At about 42 minutes following closest approach, the WAC will acquire a 3x3, 11-filter, full- planet mosaic with an average resolution of 2.5 km/pixel. Two NAC mosaics of the entire departing planet will be acquired beginning about 66 minutes after closest approach, with resolutions of 500-700 m/pixel. About 89 minutes following closest approach, the WAC will acquire a multispectral image set with a resolution of about 5 km/pixel. Following this WAC image set, MDIS will continue to acquire occasional images with both the WAC and NAC until 20 hours after closest approach, at which time the flyby data will begin being transmitted to Earth.

  4. Estimating aboveground biomass in the boreal forests of the Yukon River Basin, Alaska

    NASA Astrophysics Data System (ADS)

    Ji, L.; Wylie, B. K.; Nossov, D.; Peterson, B.; Waldrop, M. P.; McFarland, J.; Alexander, H. D.; Mack, M. C.; Rover, J. A.; Chen, X.

    2011-12-01

    Quantification of aboveground biomass (AGB) in Alaska's boreal forests is essential to accurately evaluate terrestrial carbon stocks and dynamics in northern high-latitude ecosystems. However, regional AGB datasets with spatially detailed information (<500 m) are not available for this extensive and remote area. Our goal was to map AGB at 30-m resolution for the boreal forests in the Yukon River Basin of Alaska using recent Landsat data and ground measurements. We collected field data in the Yukon River Basin from 2008 to 2010. Ground measurements included diameter at breast height (DBH) or basal diameter (BD) for live and dead trees and shrubs (>1 m tall), which were converted to plot-level AGB using allometric equations. We acquired Landsat Enhanced Thematic Mapper Plus (ETM+) images from the Web Enabled Landsat Data (WELD) that provides multi-date composites of top-of-atmosphere reflectance and brightness temperature for Alaska. From the WELD images, we generated a three-year (2008 - 2010) image composite for the Yukon River Basin using a series of compositing criteria including non-saturation, non-cloudiness, maximal normalize difference vegetation index (NDVI), and maximal brightness temperature. Airborne lidar datasets were acquired for two sub-regions in the central basin in 2009, which were converted to vegetation height datasets using the bare-earth digital surface model (DSM) and the first-return DSM. We created a multiple regression model in which the response variable was the field-observed AGB and the predictor variables were Landsat-derived reflectance, brightness temperature, and spectral vegetation indices including NDVI, soil adjusted vegetation index (SAVI), enhanced vegetation index (EVI), normalized difference infrared index (NDII), and normalized difference water index (NDWI). Principal component analysis was incorporated in the regression model to remedy the multicollinearity problems caused by high correlations between predictor variables. The model fitted the observed data well with an R-square of 0.62, mean absolute error of 29.1 Mg/ha, and mean bias error of 3.9 Mg/ha. By applying this model to the Landsat mosaic, we generated a 30-m AGB map for the boreal forests in the Yukon River Basin. Validation of the Landsat-derived AGB using the lidar dataset indicated a significant correlation between the AGB estimates and the lidar-derived canopy height. The production of a basin-wide boreal forest AGB dataset will provide an important biophysical parameter for the modeling and investigation of Alaska's ecosystems.

  5. Towards a Fault-based SHA in the Southern Upper Rhine Graben

    NASA Astrophysics Data System (ADS)

    Baize, Stéphane; Reicherter, Klaus; Thomas, Jessica; Chartier, Thomas; Cushing, Edward Marc

    2016-04-01

    A brief overview at a seismic map of the Upper Rhine Graben area (say between Strasbourg and Basel) reveals that the region is seismically active. The area has been hit recently by shallow and moderate quakes but, historically, strong quakes damaged and devastated populated zones. Several authors previously suggested, through preliminary geomorphological and geophysical studies, that active faults could be traced along the eastern margin of the graben. Thus, fault-based PSHA (probabilistic seismic hazard assessment) studies should be developed. Nevertheless, most of the input data in fault-based PSHA models are highly uncertain, based upon sparse or hypothetical data. Geophysical and geological data document the presence of post-Tertiary westward dipping faults in the area. However, our first investigations suggest that the available surface fault map do not provide a reliable document of Quaternary fault traces. Slip rate values that can be currently used in fault-PSHA models are based on regional stratigraphic data, but these include neither detailed datings nor clear base surface contours. Several hints on fault activity do exist and we have now relevant tools and techniques to figure out the activity of the faults of concern. Our preliminary analyses suggest that the LiDAR topography can adequately image the fault segments and, thanks to detailed geomorphological analysis, these data allow tracking cumulative fault offsets. Because the fault models can therefore be considered highly uncertain, our coming project for the next 3 years is to acquire and analyze these accurate topographical data, to trace the active faults and to determine slip rates through relevant features dating. Eventually, we plan to find a key site to perform a paleoseismological trench because this approach has been proved to be worth in the Graben, both to the North (Wörms and Strasbourg) and to the South (Basel). This would be done in order to definitely prove whether the faults ruptured the ground surface during the Quaternary, and in order to determine key fault parameters such as magnitude and age of large events.

  6. How Did Light Acquire a Velocity?

    ERIC Educational Resources Information Center

    Lauginie, Pierre

    2013-01-01

    We discuss how light acquired a velocity through history, from the ancient Greeks to the early modern era. Combining abstract debates, models of light, practical needs, planned research and chance, this history illustrates several key points that should be brought out in science education.

  7. Genome biogeography reveals the intraspecific spread of adaptive mutations for a complex trait.

    PubMed

    Olofsson, Jill K; Bianconi, Matheus; Besnard, Guillaume; Dunning, Luke T; Lundgren, Marjorie R; Holota, Helene; Vorontsova, Maria S; Hidalgo, Oriane; Leitch, Ilia J; Nosil, Patrik; Osborne, Colin P; Christin, Pascal-Antoine

    2016-12-01

    Physiological novelties are often studied at macro-evolutionary scales such that their micro-evolutionary origins remain poorly understood. Here, we test the hypothesis that key components of a complex trait can evolve in isolation and later be combined by gene flow. We use C 4 photosynthesis as a study system, a derived physiology that increases plant productivity in warm, dry conditions. The grass Alloteropsis semialata includes C 4 and non-C 4 genotypes, with some populations using laterally acquired C 4 -adaptive loci, providing an outstanding system to track the spread of novel adaptive mutations. Using genome data from C 4 and non-C 4 A. semialata individuals spanning the species' range, we infer and date past migrations of different parts of the genome. Our results show that photosynthetic types initially diverged in isolated populations, where key C 4 components were acquired. However, rare but recurrent subsequent gene flow allowed the spread of adaptive loci across genetic pools. Indeed, laterally acquired genes for key C 4 functions were rapidly passed between populations with otherwise distinct genomic backgrounds. Thus, our intraspecific study of C 4 -related genomic variation indicates that components of adaptive traits can evolve separately and later be combined through secondary gene flow, leading to the assembly and optimization of evolutionary innovations. © 2016 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd.

  8. Road and Roadside Feature Extraction Using Imagery and LIDAR Data for Transportation Operation

    NASA Astrophysics Data System (ADS)

    Ural, S.; Shan, J.; Romero, M. A.; Tarko, A.

    2015-03-01

    Transportation agencies require up-to-date, reliable, and feasibly acquired information on road geometry and features within proximity to the roads as input for evaluating and prioritizing new or improvement road projects. The information needed for a robust evaluation of road projects includes road centerline, width, and extent together with the average grade, cross-sections, and obstructions near the travelled way. Remote sensing is equipped with a large collection of data and well-established tools for acquiring the information and extracting aforementioned various road features at various levels and scopes. Even with many remote sensing data and methods available for road extraction, transportation operation requires more than the centerlines. Acquiring information that is spatially coherent at the operational level for the entire road system is challenging and needs multiple data sources to be integrated. In the presented study, we established a framework that used data from multiple sources, including one-foot resolution color infrared orthophotos, airborne LiDAR point clouds, and existing spatially non-accurate ancillary road networks. We were able to extract 90.25% of a total of 23.6 miles of road networks together with estimated road width, average grade along the road, and cross sections at specified intervals. Also, we have extracted buildings and vegetation within a predetermined proximity to the extracted road extent. 90.6% of 107 existing buildings were correctly identified with 31% false detection rate.

  9. Supplement Analysis for the Watershed Management Program EIS (DOE/EIS-0265/SA-66)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    N /A

    2001-10-04

    BPA proposes to fund four projects that will enhance instream flow in several subbasins throughout Oregon. The Oregon Water Trust acquires existing water rights on a voluntary basis through purchase, gift and water conservation projects, and converts the rights to instream flow under Oregon state water law. The proposed projects are all related to an on-going program of water rights acquisition in the Columbia Plateau Basin (Deschutes, John Day, Umatilla and Walla Walla subbasins) and the Columbia Gorge Basin (Fifteenmile subbasin) by the Oregon Water Trust (OWT). The current funding cycle extends through fiscal year 2001. Additional funding is currentlymore » being sought for fiscal years 2002-2004. Specific acquisition transactions are evaluated throughout the duration of the project, so on-the-ground impacts may only be estimated. The proposed project is an extension of previous water rights acquisition projects within the subject subbasins, dating back to 1994. The objective of the proposed projects in the next cycle, 2002 through 2004, is to acquire a total of approximately 12.6 cfs on tributary streams within the subbasins. The target level of water rights acquired, by subbasin, are as follows: Deschutes subbasin--2.0 cfs; Fifteenmile subbasin--1.4 cfs; John Day subbasin--2.0 cfs; Umatilla subbasin--1.0 cfs; Walla Walla subbasin--4.2 cfs; and newly prioritized streams within the region--2.0 cfs.« less

  10. Metabolite-cycled density-weighted concentric rings k-space trajectory (DW-CRT) enables high-resolution 1 H magnetic resonance spectroscopic imaging at 3-Tesla.

    PubMed

    Steel, Adam; Chiew, Mark; Jezzard, Peter; Voets, Natalie L; Plaha, Puneet; Thomas, Michael Albert; Stagg, Charlotte J; Emir, Uzay E

    2018-05-17

    Magnetic resonance spectroscopic imaging (MRSI) is a promising technique in both experimental and clinical settings. However, to date, MRSI has been hampered by prohibitively long acquisition times and artifacts caused by subject motion and hardware-related frequency drift. In the present study, we demonstrate that density weighted concentric ring trajectory (DW-CRT) k-space sampling in combination with semi-LASER excitation and metabolite-cycling enables high-resolution MRSI data to be rapidly acquired at 3 Tesla. Single-slice full-intensity MRSI data (short echo time (TE) semi-LASER TE = 32 ms) were acquired from 6 healthy volunteers with an in-plane resolution of 5 × 5 mm in 13 min 30 sec using this approach. Using LCModel analysis, we found that the acquired spectra allowed for the mapping of total N-acetylaspartate (median Cramer-Rao Lower Bound [CRLB] = 3%), glutamate+glutamine (8%), and glutathione (13%). In addition, we demonstrate potential clinical utility of this technique by optimizing the TE to detect 2-hydroxyglutarate (long TE semi-LASER, TE = 110 ms), to produce relevant high-resolution metabolite maps of grade III IDH-mutant oligodendroglioma in a single patient. This study demonstrates the potential utility of MRSI in the clinical setting at 3 Tesla.

  11. Risk factors for health care-associated infections: From better knowledge to better prevention.

    PubMed

    Ferreira, Etelvina; Pina, Elaine; Sousa-Uva, Mafalda; Sousa-Uva, António

    2017-10-01

    Health care-associated infections (HCAIs) are preventable with adoption of recognized preventive measures. The first step is to identify patients at higher risk of HCAI. This study aimed to identify patient risk factors (RFs) present on admission and acquired during inpatient stay which could be associated with higher risk of acquiring HCAI. A case-control study was conducted in adult patients admitted during 2011 who were hospitalized for >48 hours. Cases were patients with HCAIs. Controls were selected in a ratio of 3:1, case matched by the admission date. The likelihood of increased HCAI was determined through binary logistic regression. RFs identified as being the more relevant for HCAI were being a man (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.2-4.7), being aged >50 years (OR, 2.9; 95% CI, 1.3-6.9), and having an insertion of a central venous line during hospital stay (OR, 12.4; 95% CI, 5.0-30.5). RFs that showed statistical significance on admission were the patient's intrinsic factors, and RFs acquired during hospitalization were extrinsic RFs. When a set of RFs were present, the presence of a central venous line proved to be the more relevant one. Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  12. Early procurement of scarlet macaws and the emergence of social complexity in Chaco Canyon, NM.

    PubMed

    Watson, Adam S; Plog, Stephen; Culleton, Brendan J; Gilman, Patricia A; LeBlanc, Steven A; Whiteley, Peter M; Claramunt, Santiago; Kennett, Douglas J

    2015-07-07

    High-precision accelerator mass spectrometer (AMS) (14)C dates of scarlet macaw (Ara macao) skeletal remains provide the first direct evidence from Chaco Canyon in northwestern New Mexico that these Neotropical birds were procured from Mesoamerica by Pueblo people as early as ∼ A.D. 900-975. Chaco was a prominent prehistoric Pueblo center with a dense concentration of multistoried great houses constructed from the 9th through early 12th centuries. At the best known great house of Pueblo Bonito, unusual burial crypts and significant quantities of exotic and symbolically important materials, including scarlet macaws, turquoise, marine shell, and cacao, suggest societal complexity unprecedented elsewhere in the Puebloan world. Scarlet macaws are known markers of social and political status among the Pueblos. New AMS (14)C-dated scarlet macaw remains from Pueblo Bonito demonstrate that these birds were acquired persistently from Mesoamerica between A.D. 900 and 1150. Most of the macaws date before the hypothesized apogeal Chacoan period (A.D. 1040-1110) to which they are commonly attributed. The 10th century acquisition of these birds is consistent with the hypothesis that more formalized status hierarchies developed with significant connections to Mesoamerica before the post-A.D. 1040 architectural florescence in Chaco Canyon.

  13. Early procurement of scarlet macaws and the emergence of social complexity in Chaco Canyon, NM

    PubMed Central

    Watson, Adam S.; Plog, Stephen; Culleton, Brendan J.; Gilman, Patricia A.; LeBlanc, Steven A.; Whiteley, Peter M.; Claramunt, Santiago; Kennett, Douglas J.

    2015-01-01

    High-precision accelerator mass spectrometer (AMS) 14C dates of scarlet macaw (Ara macao) skeletal remains provide the first direct evidence from Chaco Canyon in northwestern New Mexico that these Neotropical birds were procured from Mesoamerica by Pueblo people as early as ∼A.D. 900–975. Chaco was a prominent prehistoric Pueblo center with a dense concentration of multistoried great houses constructed from the 9th through early 12th centuries. At the best known great house of Pueblo Bonito, unusual burial crypts and significant quantities of exotic and symbolically important materials, including scarlet macaws, turquoise, marine shell, and cacao, suggest societal complexity unprecedented elsewhere in the Puebloan world. Scarlet macaws are known markers of social and political status among the Pueblos. New AMS 14C-dated scarlet macaw remains from Pueblo Bonito demonstrate that these birds were acquired persistently from Mesoamerica between A.D. 900 and 1150. Most of the macaws date before the hypothesized apogeal Chacoan period (A.D. 1040–1110) to which they are commonly attributed. The 10th century acquisition of these birds is consistent with the hypothesis that more formalized status hierarchies developed with significant connections to Mesoamerica before the post-A.D. 1040 architectural florescence in Chaco Canyon. PMID:26100874

  14. Enteric disease episodes and the risk of acquiring a future sexually transmitted infection: a prediction model in Montreal residents.

    PubMed

    Caron, Melissa; Allard, Robert; Bédard, Lucie; Latreille, Jérôme; Buckeridge, David L

    2016-11-01

    The sexual transmission of enteric diseases poses an important public health challenge. We aimed to build a prediction model capable of identifying individuals with a reported enteric disease who could be at risk of acquiring future sexually transmitted infections (STIs). Passive surveillance data on Montreal residents with at least 1 enteric disease report was used to construct the prediction model. Cases were defined as all subjects with at least 1 STI report following their initial enteric disease episode. A final logistic regression prediction model was chosen using forward stepwise selection. The prediction model with the greatest validity included age, sex, residential location, number of STI episodes experienced prior to the first enteric disease episode, type of enteric disease acquired, and an interaction term between age and male sex. This model had an area under the curve of 0.77 and had acceptable calibration. A coordinated public health response to the sexual transmission of enteric diseases requires that a distinction be made between cases of enteric diseases transmitted through sexual activity from those transmitted through contaminated food or water. A prediction model can aid public health officials in identifying individuals who may have a higher risk of sexually acquiring a reportable disease. Once identified, these individuals could receive specialized intervention to prevent future infection. The information produced from a prediction model capable of identifying higher risk individuals can be used to guide efforts in investigating and controlling reported cases of enteric diseases and STIs. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  15. A written consent form dating back to 1524 in Bursa Ser'iye (Sharia Court) records and a proposal of a new start date for consent forms.

    PubMed

    Sayligil, Omur; Ozden, Hilmi

    2014-01-01

    Qadi registers are important documents for Ottoman medical history re.search. "Sharia Court Records (Ser'iyye Sicilleri)" are notebooks that include the records that qadis kept with regard to their decisions and deeds. These registers are the only authentic sources from which to acquire information on rural life, away from the center of the town, and to understand the daily practices of the Ottoman society. The objective of this study is to provide evidence for the fact that the concept of informed consent on medical interventions, and hence the written consent documents arranged between patients and physicians, dates back to older times in our history when compared to the Western world. A large number of Ser'iyye (Sharia Court) record originals have been surveyed. The consent form registered as A-40. 221a in Ser'iyye (Sharia Court) Records found in Bursa has been presented here as the earliest consent document found by the authors. Transcription of the original document has been performed and analyzed. The aforementioned consent form dates back to 26/Dhu al-Qi'dah/933 (August 24, 1524). The original version of the referenced consent document is the earliest consent document presented so far to the best of the authors' knowledge; it was found in Bursa Ser'iyye Records and evaluated accordingly. Based on the document, it is argued that the history of consent forms dates back about 500 years. Obtaining consent in scientific research from human beings was considered to have originated from the Nuremberg Code (1949). However, with this study, it has been shown that the concept of informed consent was already present in the Ottoman Period, during the 16th century, and that the original consent document dates back to 1524, pertaining to a surgical intervention.

  16. The Domestication Syndrome in Phoenix dactylifera Seeds: Toward the Identification of Wild Date Palm Populations

    PubMed Central

    Gros-Balthazard, Muriel; Newton, Claire; Ivorra, Sarah; Pierre, Marie-Hélène; Terral, Jean-Frédéric

    2016-01-01

    Investigating crop origins is a priority to understand the evolution of plants under domestication, develop strategies for conservation and valorization of agrobiodiversity and acquire fundamental knowledge for cultivar improvement. The date palm (Phoenix dactylifera L.) belongs to the genus Phoenix, which comprises 14 species morphologically very close, sometimes hardly distinguishable. It has been cultivated for millennia in the Middle East and in North Africa and constitutes the keystone of oasis agriculture. Yet, its origins remain poorly understood as no wild populations are identified. Uncultivated populations have been described but they might represent feral, i.e. formerly cultivated, abandoned forms rather than truly wild populations. In this context, this study based on morphometrics applied to 1625 Phoenix seeds aims to (1) differentiate Phoenix species and (2) depict the domestication syndrome observed in cultivated date palm seeds using other Phoenix species as a “wild” reference. This will help discriminate truly wild from feral forms, thus providing new insights into the evolutionary history of this species. Seed size was evaluated using four parameters: length, width, thickness and dorsal view surface. Seed shape was quantified using outline analyses based on the Elliptic Fourier Transform method. The size and shape of seeds allowed an accurate differentiation of Phoenix species. The cultivated date palm shows distinctive size and shape features, compared to other Phoenix species: seeds are longer and elongated. This morphological shift may be interpreted as a domestication syndrome, resulting from the long-term history of cultivation, selection and human-mediated dispersion. Based on seed attributes, some uncultivated date palms from Oman may be identified as wild. This opens new prospects regarding the possible existence and characterization of relict wild populations and consequently for the understanding of the date palm origins. Finally, we here describe a pipeline for the identification of the domestication syndrome in seeds that could be used in other crops. PMID:27010707

  17. The Domestication Syndrome in Phoenix dactylifera Seeds: Toward the Identification of Wild Date Palm Populations.

    PubMed

    Gros-Balthazard, Muriel; Newton, Claire; Ivorra, Sarah; Pierre, Marie-Hélène; Pintaud, Jean-Christophe; Terral, Jean-Frédéric

    2016-01-01

    Investigating crop origins is a priority to understand the evolution of plants under domestication, develop strategies for conservation and valorization of agrobiodiversity and acquire fundamental knowledge for cultivar improvement. The date palm (Phoenix dactylifera L.) belongs to the genus Phoenix, which comprises 14 species morphologically very close, sometimes hardly distinguishable. It has been cultivated for millennia in the Middle East and in North Africa and constitutes the keystone of oasis agriculture. Yet, its origins remain poorly understood as no wild populations are identified. Uncultivated populations have been described but they might represent feral, i.e. formerly cultivated, abandoned forms rather than truly wild populations. In this context, this study based on morphometrics applied to 1625 Phoenix seeds aims to (1) differentiate Phoenix species and (2) depict the domestication syndrome observed in cultivated date palm seeds using other Phoenix species as a "wild" reference. This will help discriminate truly wild from feral forms, thus providing new insights into the evolutionary history of this species. Seed size was evaluated using four parameters: length, width, thickness and dorsal view surface. Seed shape was quantified using outline analyses based on the Elliptic Fourier Transform method. The size and shape of seeds allowed an accurate differentiation of Phoenix species. The cultivated date palm shows distinctive size and shape features, compared to other Phoenix species: seeds are longer and elongated. This morphological shift may be interpreted as a domestication syndrome, resulting from the long-term history of cultivation, selection and human-mediated dispersion. Based on seed attributes, some uncultivated date palms from Oman may be identified as wild. This opens new prospects regarding the possible existence and characterization of relict wild populations and consequently for the understanding of the date palm origins. Finally, we here describe a pipeline for the identification of the domestication syndrome in seeds that could be used in other crops.

  18. Direct and indirect genetic and fine-scale location effects on breeding date in song sparrows.

    PubMed

    Germain, Ryan R; Wolak, Matthew E; Arcese, Peter; Losdat, Sylvain; Reid, Jane M

    2016-11-01

    Quantifying direct and indirect genetic effects of interacting females and males on variation in jointly expressed life-history traits is central to predicting microevolutionary dynamics. However, accurately estimating sex-specific additive genetic variances in such traits remains difficult in wild populations, especially if related individuals inhabit similar fine-scale environments. Breeding date is a key life-history trait that responds to environmental phenology and mediates individual and population responses to environmental change. However, no studies have estimated female (direct) and male (indirect) additive genetic and inbreeding effects on breeding date, and estimated the cross-sex genetic correlation, while simultaneously accounting for fine-scale environmental effects of breeding locations, impeding prediction of microevolutionary dynamics. We fitted animal models to 38 years of song sparrow (Melospiza melodia) phenology and pedigree data to estimate sex-specific additive genetic variances in breeding date, and the cross-sex genetic correlation, thereby estimating the total additive genetic variance while simultaneously estimating sex-specific inbreeding depression. We further fitted three forms of spatial animal model to explicitly estimate variance in breeding date attributable to breeding location, overlap among breeding locations and spatial autocorrelation. We thereby quantified fine-scale location variances in breeding date and quantified the degree to which estimating such variances affected the estimated additive genetic variances. The non-spatial animal model estimated nonzero female and male additive genetic variances in breeding date (sex-specific heritabilities: 0·07 and 0·02, respectively) and a strong, positive cross-sex genetic correlation (0·99), creating substantial total additive genetic variance (0·18). Breeding date varied with female, but not male inbreeding coefficient, revealing direct, but not indirect, inbreeding depression. All three spatial animal models estimated small location variance in breeding date, but because relatedness and breeding location were virtually uncorrelated, modelling location variance did not alter the estimated additive genetic variances. Our results show that sex-specific additive genetic effects on breeding date can be strongly positively correlated, which would affect any predicted rates of microevolutionary change in response to sexually antagonistic or congruent selection. Further, we show that inbreeding effects on breeding date can also be sex specific and that genetic effects can exceed phenotypic variation stemming from fine-scale location-based variation within a wild population. © 2016 The Authors. Journal of Animal Ecology © 2016 British Ecological Society.

  19. Biogeographic Dating of Speciation Times Using Paleogeographically Informed Processes

    PubMed Central

    Landis, Michael J.

    2017-01-01

    Abstract Standard models of molecular evolution cannot estimate absolute speciation times alone, and require external calibrations to do so, such as fossils. Because fossil calibration methods rely on the incomplete fossil record, a great number of nodes in the tree of life cannot be dated precisely. However, many major paleogeographical events are dated, and since biogeographic processes depend on paleogeographical conditions, biogeographic dating may be used as an alternative or complementary method to fossil dating. I demonstrate how a time-stratified biogeographic stochastic process may be used to estimate absolute divergence times by conditioning on dated paleogeographical events. Informed by the current paleogeographical literature, I construct an empirical dispersal graph using 25 areas and 26 epochs for the past 540 Ma of Earth’s history. Simulations indicate biogeographic dating performs well so long as paleogeography imposes constraint on biogeographic character evolution. To gauge whether biogeographic dating may be of practical use, I analyzed the well-studied turtle clade (Testudines) to assess how well biogeographic dating fares when compared to fossil-calibrated dating estimates reported in the literature. Fossil-free biogeographic dating estimated the age of the most recent common ancestor of extant turtles to be from the Late Triassic, which is consistent with fossil-based estimates. Dating precision improves further when including a root node fossil calibration. The described model, paleogeographical dispersal graph, and analysis scripts are available for use with RevBayes. PMID:27155009

  20. Palaeomagnetic dating method accounting for post-depositional remanence and its application to geomagnetic field modelling

    NASA Astrophysics Data System (ADS)

    Nilsson, A.; Suttie, N.

    2016-12-01

    Sedimentary palaeomagnetic data may exhibit some degree of smoothing of the recorded field due to the gradual processes by which the magnetic signal is `locked-in' over time. Here we present a new Bayesian method to construct age-depth models based on palaeomagnetic data, taking into account and correcting for potential lock-in delay. The age-depth model is built on the widely used "Bacon" dating software by Blaauw and Christen (2011, Bayesian Analysis 6, 457-474) and is designed to combine both radiocarbon and palaeomagnetic measurements. To our knowledge, this is the first palaeomagnetic dating method that addresses the potential problems related post-depositional remanent magnetisation acquisition in age-depth modelling. Age-depth models, including site specific lock-in depth and lock-in filter function, produced with this method are shown to be consistent with independent results based on radiocarbon wiggle match dated sediment sections. Besides its primary use as a dating tool, our new method can also be used specifically to identify the most likely lock-in parameters for a specific record. We explore the potential to use these results to construct high-resolution geomagnetic field models based on sedimentary palaeomagnetic data, adjusting for smoothing induced by post-depositional remanent magnetisation acquisition. Potentially, this technique could enable reconstructions of Holocene geomagnetic field with the same amplitude of variability observed in archaeomagnetic field models for the past three millennia.

  1. An examination of environmental and genetic contributions to the determinants of suicidal behavior among male twins

    PubMed Central

    Smith, April Rose; Ribeiro, Jessica; Mikolajewski, Amy; Taylor, Jeanette; Joiner, Thomas; Iacono, William G.

    2012-01-01

    The purpose of the present study was to examine the relative association of genetic and environmental factors with individual differences in each of the proximal, jointly necessary, and sufficient causes for suicidal behavior, according to the Interpersonal-Psychological Theory of Suicide (IPTS; Joiner, 2005). We examined data on derived scales measuring acquired capability, belongingness, and burdensomeness (the determinants of suicidal behavior, according to theory) from 348 adolescent male twins. Univariate biometrical models were used to estimate the magnitude of additive genetic (A), non-additive genetic (D), shared environmental (C), and nonshared environmental (E) effects associated with the variance in acquired capability, belongingness, and burdensomeness. The best fitting model for the acquired capability allowed for additive genetic and environmental effects, whereas the best fitting model for burdensomeness and belongingness allowed for shared and nonshared environmental effects. The present research extends prior work by specifying the environmental and genetic contributions to the components of the IPTS, and our findings suggest that belongingness and burdensomeness may be more appropriate targets for clinical intervention than acquired capability as these factors may be more malleable or amenable to change. PMID:22417928

  2. How trait anxiety, interpretation bias and memory affect acquired fear in children learning about new animals.

    PubMed

    Field, Zoë C; Field, Andy P

    2013-06-01

    Cognitive models of vulnerability to anxiety propose that information processing biases such as interpretation bias play a part in the etiology and maintenance of anxiety disorders. However, at present little is known about the role of memory in information processing accounts of child anxiety. The current study investigates the relationships between interpretation biases, memory and fear responses when learning about new stimuli. Children (aged 8-11 years) were presented with ambiguous information regarding a novel animal, and their fear, interpretation bias, and memory for the information was measured. The main findings were: (1) trait anxiety and interpretation bias significantly predicted acquired fear; (2) interpretation bias did not significantly mediate the relationship between trait anxiety and acquired fear; (3) interpretation bias appeared to be a more important predictor of acquired fear than trait anxiety per se; and (4) the relationship between interpretation bias and acquired fear was not mediated by the number of negative memories but was mediated by the number of positive and false-positive memories. The findings suggest that information processing models of child anxiety need to explain the role of positive memory in the formation of fear responses.

  3. Near-infrared Spectroscopic Observations of Comet C/2013 R1 (Lovejoy) by WINERED: CN Red-system Band Emission

    NASA Astrophysics Data System (ADS)

    Shinnaka, Yoshiharu; Kawakita, Hideyo; Kondo, Sohei; Ikeda, Yuji; Kobayashi, Naoto; Hamano, Satoshi; Sameshima, Hiroaki; Fukue, Kei; Matsunaga, Noriyuki; Yasui, Chikako; Izumi, Natsuko; Mizumoto, Misaki; Otsubo, Shogo; Takenaka, Keiichi; Watase, Ayaka; Kawanishi, Takafumi; Nakanishi, Kenshi; Nakaoka, Tetsuya

    2017-08-01

    Although high-resolution spectra of the CN red-system band are considered useful in cometary sciences, e.g., in the study of isotopic ratios of carbon and nitrogen in cometary volatiles, there have been few reports to date due to the lack of high-resolution (R ≡ λ/Δλ > 20,000) spectrographs in the near-infrared region around ˜1 μm. Here, we present the high-resolution emission spectrum of the CN red-system band in comet C/2013 R1 (Lovejoy), acquired by the near-infrared high-resolution spectrograph WINERED mounted on the 1.3 m Araki telescope at the Koyama Astronomical Observatory, Kyoto, Japan. We applied our fluorescence excitation models for CN, based on modern spectroscopic studies, to the observed spectrum of comet C/2013 R1 (Lovejoy) to search for CN isotopologues (13C14N and 12C15N). We used a CN fluorescence excitation model involving both a “pure” fluorescence excitation model for the outer coma and a “fully collisional” fluorescence excitation model for the inner coma region. Our emission model could reproduce the observed 12C14N red-system band of comet C/2013 R1 (Lovejoy). The derived mixing ratio between the two excitation models was 0.94(+0.02/-0.03):0.06(+0.03/-0.02), corresponding to the radius of the collision-dominant region of ˜800-1600 km from the nucleus. No isotopologues were detected. The observed spectrum is consistent, within error, with previous estimates in comets of 12C/13C (˜90) and 14N/15N (˜150).

  4. Poster — Thur Eve — 46: Monte Carlo model of the Novalis Classic 6MV stereotactic linear accelerator using the GATE simulation platform

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wiebe, J; Department of Physics and Astronomy, University of Calgary, Calgary, AB; Ploquin, N

    2014-08-15

    Monte Carlo (MC) simulation is accepted as the most accurate method to predict dose deposition when compared to other methods in radiation treatment planning. Current dose calculation algorithms used for treatment planning can become inaccurate when small radiation fields and tissue inhomogeneities are present. At our centre the Novalis Classic linear accelerator (linac) is used for Stereotactic Radiosurgery (SRS). The first MC model to date of the Novalis Classic linac was developed at our centre using the Geant4 Application for Tomographic Emission (GATE) simulation platform. GATE is relatively new, open source MC software built from CERN's Geometry and Tracking 4more » (Geant4) toolkit. The linac geometry was modeled using manufacturer specifications, as well as in-house measurements of the micro MLC's. Among multiple model parameters, the initial electron beam was adjusted so that calculated depth dose curves agreed with measured values. Simulations were run on the European Grid Infrastructure through GateLab. Simulation time is approximately 8 hours on GateLab for a complete head model simulation to acquire a phase space file. Current results have a majority of points within 3% of the measured dose values for square field sizes ranging from 6×6 mm{sup 2} to 98×98 mm{sup 2} (maximum field size on the Novalis Classic linac) at 100 cm SSD. The x-ray spectrum was determined from the MC data as well. The model provides an investigation into GATE'S capabilities and has the potential to be used as a research tool and an independent dose calculation engine for clinical treatment plans.« less

  5. Characterizing GEO Titan IIIC Transtage Fragmentations using Ground-Based and Telescopic Measurements

    NASA Technical Reports Server (NTRS)

    Cowardin, Heather; Anz-Meador, Phillip; Reyes, Jacqueline A.

    2017-01-01

    In a continued effort to better characterize the geosynchronous orbit (GEO) environment, NASA's Orbital Debris Program Office (ODPO) utilizes various ground-based optical assets to acquire photometric and spectral data of known debris associated with fragmentations in or near GEO. The Titan IIIC Transtage upper stage is known to have fragmented four times. Two of the four fragmentations were in GEO while the Transtage fragmented a third time in GEO transfer orbit. The forth fragmentation occurred in low Earth orbit. To better assess and characterize these fragmentations, the NASA ODPO acquired a Titan Transtage test and display article previously in the custody of the 309th Aerospace Maintenance and Regeneration Group (AMARG) in Tucson, Arizona. After initial inspections at AMARG demonstrated that it was of sufficient fidelity to be of interest, the test article was brought to NASA Johnson Space Center (JSC) to continue material analysis and historical documentation. The Transtage has undergone two separate spectral measurement campaigns to characterize the reflectance spectroscopy of historical aerospace materials. These data have been incorporated into the NASA Spectral Database, with the goal of using telescopic data comparisons for potential material identification. A Light Detection and Ranging (LIDAR) system scan also has been completed and a scale model has been created for use in the Optical Measurement Center (OMC) for photometric analysis of an intact Transtage, including bidirectional reflectance distribution function (BRDF) measurements. An historical overview of the Titan IIIC Transtage, the current analysis that has been done to date, and the future work to be completed in support of characterizing the GEO and near GEO orbital debris environment will be discussed in the subsequent presentation.

  6. Geomorphological and structural characterization of the southern Weihe Graben, central China: Implications for fault segmentation

    NASA Astrophysics Data System (ADS)

    Cheng, Yali; He, Chuanqi; Rao, Gang; Yan, Bing; Lin, Aiming; Hu, Jianmin; Yu, Yangli; Yao, Qi

    2018-01-01

    The Cenozoic graben systems around the tectonically stable Ordos Block, central China, have been considered as ideal places for investigating active deformation within continental rifts, such as the Weihe Graben at the southern margin with high historical seismicity (e.g., 1556 M 8.5 Huaxian great earthquake). However, previous investigations have mostly focused on the active structures in the eastern and northern parts of this graben. By contrast, in the southwest, tectonic activity along the northern margin of the Qinling Mountains has not been systematically investigated yet. In this study, based on digital elevation models (DEMs), we carried out geomorphological analysis to evaluate the relative tectonic activity along the whole South Border Fault (SBF). On the basis of field observations, high resolution DEMs acquired by small unmanned aerial vehicles (sUVA) using structure-for-motion techniques, radiocarbon (14C) age dating, we demonstrate that: 1) Tectonic activity along the SBF changes along strike, being higher in the eastern sector. 2) Seven major segment boundaries have been assigned, where the fault changes its strike and has lower tectonic activity. 3) The fault segment between the cities of Huaxian and Huayin characterized by almost pure normal slip has been active during the Holocene. We suggest that these findings would provide a basis for further investigating on the seismic risk in densely-populated Weihe Graben. Table S2. The values and classification of geomorphic indices obtained in this study. Fig. S1. Morphological features of the stream long profiles (Nos. 1-75) and corresponding SLK values. Fig. S2. Comparison of geomorphological parameters acquired from different DEMs (90-m SRTM and 30-m ASTER GDEM): (a) HI values; (b) HI linear regression; (c) mean slope of drainage basin; (d) mean slope linear regression.

  7. Bathymetry Offshore Sumatra First Comprehensive map of International Data Sets

    NASA Astrophysics Data System (ADS)

    Gaedicke, C.; Ladage, S.; Soh, W.; Weinrebe, W.; Tappin, D. R.; Henstock, T.; McNeill, L.; Sibuet, J.; Klingelhoefer, F.; Singh, S.; Flueh, E.; Djajadihardja, Y.

    2006-12-01

    Knowledge of the bathymetry offshore Sumatra is of great importance for geohazard risk assessment, modelling of tsunami runup heights and development of tsunami early warning systems as well as for the general understanding of plate boundary processes and morphotectonic features. Since the devastating December 26, 2004 Sumatra-Andaman Islands earthquake and tsunami a number of marine expeditions, funded by Canada, France, Germany, India, Indonesia, Japan, United Kingdom and the United States have acquired bathymetric data over the southern part of the earthquake rupture zone but also along strike the whole Sunda trench. Here we present the first compilation of these bathymetric data sets as one bathymetric map. The bathymetric data acquired up to date covers a vast part of the trench, continental slope and in part also of the fore arc basins. The map incorporates the newest data sets from 2005 of the British high-resolution HMS SCOTT survey, the French Marion-Dufresene "Aftershocks" and the Japanese Natsushima cruises. While these surveys concentrated on the southern rupture zone of the Dec. 26th, 2004 earthquake, the German RV SONNE SeaCause and Sumatra cruises in 2005 and 2006 mapped the March 28th 2005 rupture area as well as large parts of the central Sunda trench and slope and in part the fore arc basins. Surveys reaching back to 1997 covering parts of the Sunda Strait and offshore southern Sumatra are also incorporated. A nearly complete coverage of the Sunda trench and slope area in the north is achieved. In the south data gaps on the slope still exist. This map compilation is a collaborative international effort initiated and partly funded by InterMARGINS. It is a major contribution to the Indonesian and international science community.

  8. Characterizing GEO Titan IIIC Transtage Fragmentations Using Ground-based and Telescopic Measurements

    NASA Astrophysics Data System (ADS)

    Cowardin, H.; Anz-Meador, P.; Reyes, J. A.

    In a continued effort to better characterize the geosynchronous orbit (GEO) environment, NASA’s Orbital Debris Program Office (ODPO) utilizes various ground-based optical assets to acquire photometric and spectral data of known debris associated with fragmentations in or near GEO. The Titan IIIC Transtage upper stage is known to have fragmented four times. Two of the four fragmentations were in GEO while the Transtage fragmented a third time in GEO transfer orbit. The forth fragmentation occurred in low Earth orbit. To better assess and characterize these fragmentations, the NASA ODPO acquired a Titan Transtage test and display article previously in the custody of the 309th Aerospace Maintenance and Regeneration Group (AMARG) in Tucson, Arizona. After initial inspections at AMARG demonstrated that it was of sufficient fidelity to be of interest, the test article was brought to NASA Johnson Space Center (JSC) to continue material analysis and historical documentation. The Transtage has undergone two separate spectral measurement campaigns to characterize the reflectance spectroscopy of historical aerospace materials. These data have been incorporated into the NASA Spectral Database, with the goal of using telescopic data comparisons for potential material identification. A Light Detection and Ranging (LIDAR) system scan also has been completed and a scale model has been created for use in the Optical Measurement Center (OMC) for photometric analysis of an intact Transtage, including bidirectional reflectance distribution function (BRDF) measurements. An historical overview of the Titan IIIC Transtage, the current analysis that has been done to date, and the future work to be completed in support of characterizing the GEO and near GEO orbital debris environment will be discussed in the subsequent presentation.

  9. Retrieval of interseismic displacement from multi-temporal InSAR measurements: challenges and solutions

    NASA Astrophysics Data System (ADS)

    Zhang, L.; Ding, X.; Lu, Z.; Wen, Y.; Hu, J.

    2016-12-01

    High-resolution measurements of interseismic displacement are critical for understanding the earthquake cycle and for assessing earthquake hazard. Compared with sparsely located GNSS sites, it is well-known that by jointly analyzing a set of data over the same area acquired on different dates, multi-temporal InSAR (MTInSAR) is capable of remotely imaging interseismic deformation at an unprecedented level of spatial resolution. However conventional MTInSAR cannot hold a considerate promise for the precise retrieval of interseismic deformation in tectonically active zones where complicated atmospheric delay, orbital errors, and localized seasonal ground fluctuations commonly exist. Of interest in this study is to develop reliable solutions to correct or suppress these unwanted signals thereby to improve the accuracy of mapped interseismic displacement. Our technical innovations lie in the following aspects. According to different spatial-temporal characteristics, a joint model that takes both orbit errors and interseismic displacement as parameters is designed to isolate long wavelength motion from orbit error even in the case these two types of signals exhibit similar spatial patterns. To suppress the localized impacts (e.g., a portion of atmospheric artifacts and small-scale anthropogenic deformation), spatial correlation is employed as a constraint during the parameter estimation. The proposed solutions are evaluated by synthetic tests and applied to map the interseismic displacement over Eastern Turkey that spans the Arabia-Eurasia plate boundary zone from a large set of radar images acquired by Envisat/ASAR and Sentinel-1. The derived interseismic displacement validated by GPS data is further used to invert the slip rate and locking depth for the North and East Anatolian Faults. A cross-comparison with published results is also conducted.

  10. Large Scale Meteorological Pattern of Extreme Rainfall in Indonesia

    NASA Astrophysics Data System (ADS)

    Kuswanto, Heri; Grotjahn, Richard; Rachmi, Arinda; Suhermi, Novri; Oktania, Erma; Wijaya, Yosep

    2014-05-01

    Extreme Weather Events (EWEs) cause negative impacts socially, economically, and environmentally. Considering these facts, forecasting EWEs is crucial work. Indonesia has been identified as being among the countries most vulnerable to the risk of natural disasters, such as floods, heat waves, and droughts. Current forecasting of extreme events in Indonesia is carried out by interpreting synoptic maps for several fields without taking into account the link between the observed events in the 'target' area with remote conditions. This situation may cause misidentification of the event leading to an inaccurate prediction. Grotjahn and Faure (2008) compute composite maps from extreme events (including heat waves and intense rainfall) to help forecasters identify such events in model output. The composite maps show large scale meteorological patterns (LSMP) that occurred during historical EWEs. Some vital information about the EWEs can be acquired from studying such maps, in addition to providing forecaster guidance. Such maps have robust mid-latitude meteorological patterns (for Sacramento and California Central Valley, USA EWEs). We study the performance of the composite approach for tropical weather condition such as Indonesia. Initially, the composite maps are developed to identify and forecast the extreme weather events in Indramayu district- West Java, the main producer of rice in Indonesia and contributes to about 60% of the national total rice production. Studying extreme weather events happening in Indramayu is important since EWEs there affect national agricultural and fisheries activities. During a recent EWE more than a thousand houses in Indramayu suffered from serious flooding with each home more than one meter underwater. The flood also destroyed a thousand hectares of rice plantings in 5 regencies. Identifying the dates of extreme events is one of the most important steps and has to be carried out carefully. An approach has been applied to identify the dates involving observations from multiple sites (rain gauges). The approach combines the POT (Peaks Over Threshold) with 'declustering' of the data to approximate independence based on the autocorrelation structure of each rainfall series. The cross correlation among sites is considered also to develop the event's criteria yielding a rational choice of the extreme dates given the 'spotty' nature of the intense convection. Based on the identified dates, we are developing a supporting tool for forecasting extreme rainfall based on the corresponding large-scale meteorological patterns (LSMPs). The LSMPs methodology focuses on the larger-scale patterns that the model are better able to forecast, as those larger-scale patterns create the conditions fostering the local EWE. Bootstrap resampling method is applied to highlight the key features that statistically significant with the extreme events. Grotjahn, R., and G. Faure. 2008: Composite Predictor Maps of Extraordinary Weather Events in the Sacramento California Region. Weather and Forecasting. 23: 313-335.

  11. Functional magnetic resonance imaging in a low-field intraoperative scanner.

    PubMed

    Schulder, Michael; Azmi, Hooman; Biswal, Bharat

    2003-01-01

    Functional magnetic resonance imaging (fMRI) has been used for preoperative planning and intraoperative surgical navigation. However, most experience to date has been with preoperative images acquired on high-field echoplanar MRI units. We explored the feasibility of acquiring fMRI of the motor cortex with a dedicated low-field intraoperative MRI (iMRI). Five healthy volunteers were scanned with the 0.12-tesla PoleStar N-10 iMRI (Odin Medical Technologies, Israel). A finger-tapping motor paradigm was performed with sequential scans, acquired alternately at rest and during activity. In addition, scans were obtained during breath holding alternating with normal breathing. The same paradigms were repeated using a 3-tesla MRI (Siemens Corp., Allandale, N.J., USA). Statistical analysis was performed offline using cross-correlation and cluster techniques. Data were resampled using the 'jackknife' process. The location, number of activated voxels and degrees of statistical significance between the two scanners were compared. With both the 0.12- and 3-tesla imagers, motor cortex activation was seen in all subjects to a significance of p < 0.02 or greater. No clustered pixels were seen outside the sensorimotor cortex. The resampled correlation coefficients were normally distributed, with a mean of 0.56 for both the 0.12- and 3-tesla scanners (standard deviations 0.11 and 0.08, respectively). The breath holding paradigm confirmed that the expected diffuse activation was seen on 0.12- and 3-tesla scans. Accurate fMRI with a low-field iMRI is feasible. Such data could be acquired immediately before or even during surgery. This would increase the utility of iMRI and allow for updated intraoperative functional imaging, free of the limitations of brain shift. Copyright 2003 S. Karger AG, Basel

  12. Clinical Definitions of Melioidosis

    PubMed Central

    Cheng, Allen C.; Currie, Bart J.; Dance, David A. B.; Funnell, Simon G. P.; Limmathurotsakul, Direk; Simpson, Andrew J. H.; Peacock, Sharon J.

    2013-01-01

    Clinical definitions of melioidosis and inhalation-acquired melioidosis (Burkholderia pseudomallei infection) are described together with the evidence used to develop these definitions. Such definitions support accurate public health reporting, preparedness planning for deliberate B. pseudomallei release, design of experimental models, and categorization of naturally acquired melioidosis. PMID:23468355

  13. An evaluation on CT image acquisition method for medical VR applications

    NASA Astrophysics Data System (ADS)

    Jang, Seong-wook; Ko, Junho; Yoo, Yon-sik; Kim, Yoonsang

    2017-02-01

    Recent medical virtual reality (VR) applications to minimize re-operations are being studied for improvements in surgical efficiency and reduction of operation error. The CT image acquisition method considering three-dimensional (3D) modeling for medical VR applications is important, because the realistic model is required for the actual human organ. However, the research for medical VR applications has focused on 3D modeling techniques and utilized 3D models. In addition, research on a CT image acquisition method considering 3D modeling has never been reported. The conventional CT image acquisition method involves scanning a limited area of the lesion for the diagnosis of doctors once or twice. However, the medical VR application is required to acquire the CT image considering patients' various postures and a wider area than the lesion. A wider area than the lesion is required because of the necessary process of comparing bilateral sides for dyskinesia diagnosis of the shoulder, pelvis, and leg. Moreover, patients' various postures are required due to the different effects on the musculoskeletal system. Therefore, in this paper, we perform a comparative experiment on the acquired CT images considering image area (unilateral/bilateral) and patients' postures (neutral/abducted). CT images are acquired from 10 patients for the experiments, and the acquired CT images are evaluated based on the length per pixel and the morphological deviation. Finally, by comparing the experiment results, we evaluate the CT image acquisition method for medical VR applications.

  14. SRTM Anaglyph: Las Bayas, Argentina

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The interplay of volcanism, stream erosion and landslides is evident in this Shuttle Radar Topography Mission view of the eastern flank of the Andes Mountains, southeast of San Carlos de Bariloche, Argentina. Older lava flows emanating from the Andes once covered much of this area. Younger, local volcanoes (seen here as small peaks) then covered parts of the area with fresh, erosion resistant flows (seen here as very smooth surfaces). Subsequent erosion has created fine patterns on the older surfaces (bottom of the image) and bolder, irregular patterns through and around the younger surfaces (upper center and right center). Meanwhile, where a large stream immediately borders the resistant plateau (center of the image), lateral erosion has undercut the resistant plateau causing slivers of it to fall into the stream channel. This scene well illustrate show topographic data alone can reveal some aspects of recent geologic history.

    This anaglyph was produced by first shading a preliminary elevation model from data acquired by the Shuttle Radar Topography Mission. The stereoscopic effect was then created by generating two differing perspectives, one for each eye. When viewed through special glasses, the result is a vertically exaggerated view of the Earth's surface in its full three dimensions. Anaglyph glasses cover the left eye with a red filter and cover the right eye with a blue filter.

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on February 11, 2000. The mission used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar that flew twice on the Space Shuttle Endeavour in 1994. The Shuttle Radar Topography Mission was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between NASA, the National Imagery and Mapping Agency of the U.S. Department of Defense, and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Earth Science Enterprise, Washington, DC.

    Size: 54.3 x 36.4 kilometers ( 33.7 x 22.6 miles) Location: 41.4 deg. South lat., 70.8 deg. West lon. Orientation: North toward the top Image Data: Shaded SRTM elevation model Date Acquired: February 2000

  15. Parametric Accuracy: Building Information Modeling Process Applied to the Cultural Heritage Preservation

    NASA Astrophysics Data System (ADS)

    Garagnani, S.; Manferdini, A. M.

    2013-02-01

    Since their introduction, modeling tools aimed to architectural design evolved in today's "digital multi-purpose drawing boards" based on enhanced parametric elements able to originate whole buildings within virtual environments. Semantic splitting and elements topology are features that allow objects to be "intelligent" (i.e. self-aware of what kind of element they are and with whom they can interact), representing this way basics of Building Information Modeling (BIM), a coordinated, consistent and always up to date workflow improved in order to reach higher quality, reliability and cost reductions all over the design process. Even if BIM was originally intended for new architectures, its attitude to store semantic inter-related information can be successfully applied to existing buildings as well, especially if they deserve particular care such as Cultural Heritage sites. BIM engines can easily manage simple parametric geometries, collapsing them to standard primitives connected through hierarchical relationships: however, when components are generated by existing morphologies, for example acquiring point clouds by digital photogrammetry or laser scanning equipment, complex abstractions have to be introduced while remodeling elements by hand, since automatic feature extraction in available software is still not effective. In order to introduce a methodology destined to process point cloud data in a BIM environment with high accuracy, this paper describes some experiences on monumental sites documentation, generated through a plug-in written for Autodesk Revit and codenamed GreenSpider after its capability to layout points in space as if they were nodes of an ideal cobweb.

  16. Paradoxical Way for Losers in a Dating Game

    NASA Astrophysics Data System (ADS)

    Arizmendi, C. M.

    2007-05-01

    We study the dating market decision problem in which men and women repeatedly go out on dates and learn about each other. We consider a model for the dating market that takes into account progressive mutual learning. This model consists of a repeated game in which agents gain an uncertain payoff from being matched with a particular person on the other side of the market in each time period. Players have a list of preferred partners on the other set. The players that reach higher rank levels on the other set preferences list have also higher probability to be accepted for dating. A question can be raised, as considered in this study: Can the less appreciated players do better? Two different kinds of dating game are combined "à la Parrondo" to foster the less attractive players. Optimism seems to be highly recommendable, especially for losers.

  17. Kinetic model-based feed-forward controlled fed-batch fermentation of Lactobacillus rhamnosus for the production of lactic acid from Arabic date juice.

    PubMed

    Choi, Minsung; Al-Zahrani, Saeed M; Lee, Sang Yup

    2014-06-01

    Arabic date is overproduced in Arabic countries such as Saudi Arabia and Iraq and is mostly composed of sugars (70-80 wt%). Here we developed a fed-batch fermentation process by using a kinetic model for the efficient production of lactic acid to a high concentration from Arabic date juice. First, a kinetic model of Lactobacillus rhamnosus grown on date juice in batch fermentation was constructed in EXCEL so that the estimation of parameters and simulation of the model can be easily performed. Then, several fed-batch fermentations were conducted by employing different feeding strategies including pulsed feeding, exponential feeding, and modified exponential feeding. Based on the results of fed-batch fermentations, the kinetic model for fed-batch fermentation was also developed. This new model was used to perform feed-forward controlled fed-batch fermentation, which resulted in the production of 171.79 g l(-1) of lactic acid with the productivity and yield of 1.58 and 0.87 g l(-1) h(-1), respectively.

  18. AgRISTARS: Supporting research. Spring small grains planting date distribution model

    NASA Technical Reports Server (NTRS)

    Hodges, T.; Artley, J. A. (Principal Investigator)

    1981-01-01

    A model was developed using 996 planting dates at 51 LANDSAT segments for spring wheat and spring barley in Minnesota, Montana, North Dakota, and South Dakota in 1979. Daily maximum and minimum temperatures and precipitation were obtained from the cooperative weather stations nearest to each segment. The model uses a growing degree day summation modified for daily temperature range to estimate the beginning of planting and uses a soil surface wetness variable to estimate how a fixed number of planting days are distributed after planting begins. For 1979, the model predicts first, median, and last planting dates with root mean square errors of 7.91, 6.61, and 7.09 days, respectively. The model also provides three or four dates to represent periods of planting activity within the planting season. Although the full model was not tested on an independent data set, it may be suitable in areas other than the U.S. Great Plains where spring small grains are planted as soon as soil and air temperatures become warm enough in the spring for plant growth.

  19. Dense Tracking and Mapping with a Quadrocopter

    NASA Astrophysics Data System (ADS)

    Sturm, J.; Bylow, E.; Kerl, C.; Kahl, F.; Cremers, D.

    2013-08-01

    In this paper, we present an approach for acquiring textured 3D models of room-sized indoor spaces using a quadrocopter. Such room models are for example useful for architects and interior designers as well as for factory planners and construction managers. The model is internally represented by a signed distance function (SDF) and the SDF is used to directly track the camera with respect to the model. Our solution enables accurate position control of the quadrocopter, so that it can automatically follow a pre-defined flight pattern. Our system provides live feedback of the acquired 3D model to the user. The final model consisting of a textured 3D triangle mesh can be saved in several standard CAD file formats.

  20. High-resolution prediction of leaf onset date in Japan in the 21st century under the IPCC A1B scenario.

    PubMed

    Hadano, Mayumi; Nasahara, Kenlo Nishida; Motohka, Takeshi; Noda, Hibiki Muraoka; Murakami, Kazutaka; Hosaka, Masahiro

    2013-06-01

    Reports indicate that leaf onset (leaf flush) of deciduous trees in cool-temperate ecosystems is occurring earlier in the spring in response to global warming. In this study, we created two types of phenology models, one driven only by warmth (spring warming [SW] model) and another driven by both warmth and winter chilling (parallel chill [PC] model), to predict such phenomena in the Japanese Islands at high spatial resolution (500 m). We calibrated these models using leaf onset dates derived from satellite data (Terra/MODIS) and in situ temperature data derived from a dense network of ground stations Automated Meteorological Data Acquisition System. We ran the model using future climate predictions created by the Japanese Meteorological Agency's MRI-AGCM3.1S model. In comparison to the first decade of the 2000s, our results predict that the date of leaf onset in the 2030s will advance by an average of 12 days under the SW model and 7 days under the PC model throughout the study area. The date of onset in the 2090s will advance by 26 days under the SW model and by 15 days under the PC model. The greatest impact will occur on Hokkaido (the northernmost island) and in the central mountains.

  1. "I definitely want grandbabies": Caregivers of adolescents with perinatally-acquired HIV reflect on dating and childbearing.

    PubMed

    Fair, Cynthia D; Albright, Jamie N; Clark, Devon M; Houpt, Bethany

    2016-12-01

    Parents and caregivers of typically developing teens are often a source of information about sexual health and relationships. However, little is known about the information offered to adolescents with perinatally acquired HIV (APHIV) by caregivers who may provide support and guidance to their teen as they explore sexuality and childbearing. This qualitative exploratory study involved the in-depth interviews of 18 caregivers (17 females), including biological mothers (9), relatives (5), and adoptive/foster mothers (4), who care for APHIV. Interviews explored views regarding their adolescent's engagement in romantic relationships, sexual behaviors, and childbearing. The guardian's knowledge of mother-to-child-transmission (MTCT) was also assessed for accuracy. Transcribed interviews were coded for emergent themes. Analyses indicated that the majority of caregivers discussed sexual health and dating with their adolescent. However, guidance regarding disclosure to partners of the adolescent's HIV status varied. Some biological mothers and all relatives cautioned against disclosure, contrary to foster/adoptive mothers. Most caregivers wanted their adolescent to experience parenthood. Reasons affirming childbearing included the belief their child would be a good parent and wanted to experience parenthood, childbearing as a normative experience, and decreased HIV-related stigma. Biological mothers and most relatives did not know the risk of MTCT, as opposed to all foster/adoptive mothers who accurately stated the risk was 1% to 2%. The type of guardian influenced the nature of shared information related to disclosure and risk of MTCT. Sexual and reproductive health education should be provided to caregivers because they could be an important source of information for APHIV. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  2. High-resolution chronology of sediment below CCD based on Holocene paleomagnetic secular variations in the Tohoku-oki earthquake rupture zone

    NASA Astrophysics Data System (ADS)

    Kanamatsu, Toshiya; Usami, Kazuko; McHugh, Cecilia M. G.; Ikehara, Ken

    2017-08-01

    Using high-resolution paleomagnetic data, we examined the potential for obtaining precise ages from sediment core samples recovered from deep-sea basins close to rupture zones of the 2011 and earlier earthquakes off Tohoku, Japan. Obtaining detailed stratigraphic ages from deep-sea sediments below the calcium compensation depth (CCD) is difficult, but we found that the samples contain excellent paleomagnetic secular variation records to constrain age models. Variations in paleomagnetic directions obtained from the sediments reveal systematic changes in the cores. A stacked paleomagnetic profile closely matches the Lake Biwa data sets in southwest Japan for the past 7000 years, one can establish age models based on secular variations of the geomagnetic field on sediments recovered uniquely below the CCD. Comparison of paleomagnetic directions near a tephra and a paleomagnetic direction of contemporaneous pyroclastic flow deposits acquired by different magnetization processes shows precise depositional ages reflecting the magnetization delay of the marine sediment record.Plain Language SummaryGenerally obtaining detailed ages from deep-sea sediments is difficult, because available dating method is very limited. We found that the deep-see sediment off North Japan recorded past sequential geomagnetic directions. If those records correlate well with the reference record in past 7000 years, then we could estimate age of sediment by pattern matching. Additionally a volcanic ash emitted in 915 A.D., which was intercalated in our samples, indicates a time lag in our age model. This observation makes our age model more precise.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://www.dtic.mil/docs/citations/ADA466385','DTIC-ST'); return false;" href="http://www.dtic.mil/docs/citations/ADA466385"><span>Low Dimensional Modeling of Zero-Net Mass-Flux Actuators</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.dtic.mil/">DTIC Science & Technology</a></p> <p></p> <p>2004-07-01</p> <p>centerline deflection of the diaphragm is measured using a laser displacement sensor (Micro-Epsilon Model ILD2000-10). Both signals are acquired phase...the flowfield emanating from the ZNMF orifice are acquired using Laser Doppler Anemometry (LDA), the details of which are listed in Table 1. The...synthetic jet actuator is mounted to a three-axis traverse with sub-micron spatial resolution. The 488 and 514.5 nm lines of an argon-ion laser are</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/10566457','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/10566457"><span>Automation and integration of components for generalized semantic markup of electronic medical texts.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Dugan, J M; Berrios, D C; Liu, X; Kim, D K; Kaizer, H; Fagan, L M</p> <p>1999-01-01</p> <p>Our group has built an information retrieval system based on a complex semantic markup of medical textbooks. We describe the construction of a set of web-based knowledge-acquisition tools that expedites the collection and maintenance of the concepts required for text markup and the search interface required for information retrieval from the marked text. In the text markup system, domain experts (DEs) identify sections of text that contain one or more elements from a finite set of concepts. End users can then query the text using a predefined set of questions, each of which identifies a subset of complementary concepts. The search process matches that subset of concepts to relevant points in the text. The current process requires that the DE invest significant time to generate the required concepts and questions. We propose a new system--called ACQUIRE (Acquisition of Concepts and Queries in an Integrated Retrieval Environment)--that assists a DE in two essential tasks in the text-markup process. First, it helps her to develop, edit, and maintain the concept model: the set of concepts with which she marks the text. Second, ACQUIRE helps her to develop a query model: the set of specific questions that end users can later use to search the marked text. The DE incorporates concepts from the concept model when she creates the questions in the query model. The major benefit of the ACQUIRE system is a reduction in the time and effort required for the text-markup process. We compared the process of concept- and query-model creation using ACQUIRE to the process used in previous work by rebuilding two existing models that we previously constructed manually. We observed a significant decrease in the time required to build and maintain the concept and query models.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3692872','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3692872"><span>A System for Surveillance Directly from the EMR</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Davies, Richard F.; Morin, Jason; Bhatia, Ramanjot S.; de Bruijn, Lambertus</p> <p>2013-01-01</p> <p>Objective Our objective was to conduct surveillance of nosocomial infections directly from multiple EMR data streams in a large multi-location Canadian health care facility. The system developed automatically triggers bed-day-level-location-aware reports and detects and tracks the incidents of nosocomial infections in hospital by ward. Introduction Hospital acquired infections are a major cause of morbidity, mortality and increased resource utilization. CDC estimates that in the US alone, over 2 million patients are affected by nosocomial infections costing approximately $34.7 billion to $45 billion annually (1). The existing process of detection and reporting relies on time consuming manual processing of records and generation of alerts based on disparate definitions that are not comparable across institutions or even physicians. Methods A multi-stakeholder team consisting of experts from medicine, infection control, epidemiology, privacy, computing, artificial intelligence, data fusion and public health conducted a proof of concept from four complete years of admission records of all patients at the University of Ottawa Heart Institute. Figure 1 lists the data elements investigated. Our system uses an open source enterprise bus ‘Mirth Connect’ to receive and store data in HL7 format. The processing of information is handled by individual components and alerts are pushed back to respective locations. The free text components were classified using natural language processing. Negation detection was performed using NegEx (2). Data-fusion algorithms were used to merge information to make it meaningful and allow complex syndrome definitions to be mapped onto the data. Results The system monitors: Ventilator Associated Pneumonia (VAP), Central Line Infections (CLI), Methicillin Resistant Staph Aureus (MRSA), Clostridium difficile (C. Diff) and Vancomycin resistant Enterococcus (VRE). 21452 hospital admissions occurred in 17670 unique patients over four years. There were 41720 CXRs performed in total, of which 10546 were classified as having an infiltrate. 4575 admissions were associated with at least one CXR showing an infiltrate, 2266 of which were hospital-acquired. Hospital acquired infiltrates were associated with an increased hospital mortality (6.3% vs 2.6%)* and length of stay (19.5 days vs 6.5 days)*. 253 patients had at least one positive blood culture. This was also associated with an increased hospital mortality (23,3% vs. 2.8%)* and length of stay (10.8 vs 40.9 days)*. (* all p values < 0.00001) Conclusions This proof of concept system demonstrates the capability of monitoring and analyzing multiple available data streams to automatically detect and track infections without the need for manual data capture and entry. It acquires directly from the EMR data to identify and classify health care events, which can be used to improve health outcomes and costs. The standardization of definitions used for detection will allow for generalization across institutions. Data element/source Microbiology Medical Record Number bacteriology requests Patient Record System bacteriology results year of birth virology request Sex virology results partial postal code Hematology Ward CBC results Transfers Biochemistry date of admission Creatinine date of discharge Pharmacy isolation/respiratory, enteric precautions status orders for antidiarrheals. antibiotics, antivirals MRSA/VRE screening status medication list Radiology Surgical Information Management System Chest x-ray requests Operative report or surgical list Chest x -ray results Other information Emergency Room Clinical Stores: Chief complaint Requests and utilization of ventilators, masks, gloves, hand sanitizer and linens Final diagnosis Payroll: CTAS code Staffing levels, absenteeism Date of ER visit</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27270845','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27270845"><span>CMS Nonpayment Policy, Quality Improvement, and Hospital-Acquired Conditions: An Integrative Review.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Bae, Sung-Heui</p> <p></p> <p>This integrative review synthesized evidence on the consequences of the Centers for Medicare & Medicaid Services (CMS) nonpayment policy on quality improvement initiatives and hospital-acquired conditions. Fourteen articles were included. This review presents strong evidence that the CMS policy has spurred quality improvement initiatives; however, the relationships between the CMS policy and hospital-acquired conditions are inconclusive. In future research, a comprehensive model of implementation of the CMS nonpayment policy would help us understand the effectiveness of this policy.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JGRC..121.7308S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JGRC..121.7308S"><span>Variability, trends, and predictability of seasonal sea ice retreat and advance in the Chukchi Sea</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Serreze, Mark C.; Crawford, Alex D.; Stroeve, Julienne C.; Barrett, Andrew P.; Woodgate, Rebecca A.</p> <p>2016-10-01</p> <p>As assessed over the period 1979-2014, the date that sea ice retreats to the shelf break (150 m contour) of the Chukchi Sea has a linear trend of -0.7 days per year. The date of seasonal ice advance back to the shelf break has a steeper trend of about +1.5 days per year, together yielding an increase in the open water period of 80 days. Based on detrended time series, we ask how interannual variability in advance and retreat dates relate to various forcing parameters including radiation fluxes, temperature and wind (from numerical reanalyses), and the oceanic heat inflow through the Bering Strait (from in situ moorings). Of all variables considered, the retreat date is most strongly correlated (r ˜ 0.8) with the April through June Bering Strait heat inflow. After testing a suite of statistical linear models using several potential predictors, the best model for predicting the date of retreat includes only the April through June Bering Strait heat inflow, which explains 68% of retreat date variance. The best model predicting the ice advance date includes the July through September inflow and the date of retreat, explaining 67% of advance date variance. We address these relationships by discussing heat balances within the Chukchi Sea, and the hypothesis of oceanic heat transport triggering ocean heat uptake and ice-albedo feedback. Developing an operational prediction scheme for seasonal retreat and advance would require timely acquisition of Bering Strait heat inflow data. Predictability will likely always be limited by the chaotic nature of atmospheric circulation patterns.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2010-09-23/pdf/2010-23841.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2010-09-23/pdf/2010-23841.pdf"><span>75 FR 57882 - Airworthiness Directives; The Boeing Company Model 737-300, -400, and -500 Series Airplanes</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2010-09-23</p> <p>... those described in Boeing Special Attention Service Bulletin 737-54-1044, dated December 10, 2007...., ``Compliance'' of Boeing Special Attention Service Bulletin 737-54- 1044, dated December 10, 2007; except... 737-54-1044, dated December 10, 2007; or Boeing Alert Service Bulletin 737-54A1044, Revision 2, dated...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.gpo.gov/fdsys/pkg/FR-2011-01-05/pdf/2010-33003.pdf','FEDREG'); return false;" href="https://www.gpo.gov/fdsys/pkg/FR-2011-01-05/pdf/2010-33003.pdf"><span>76 FR 426 - Airworthiness Directives; The Boeing Company Model 737-300, -400, and -500 Series Airplanes</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.gpo.gov/fdsys/browse/collection.action?collectionCode=FR">Federal Register 2010, 2011, 2012, 2013, 2014</a></p> <p></p> <p>2011-01-05</p> <p>...., ``Compliance'' of Boeing Special Attention Service Bulletin 737-54- 1044, dated December 10, 2007; except... 737-54-1044, dated December 10, 2007; or Boeing Alert Service Bulletin 737-54A1044, Revision 2, dated... time specified in paragraph 1.E. of Boeing Special Attention Service Bulletin 737-54-1044, dated...</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25711614','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25711614"><span>The Role of Parent Communication and Connectedness in Dating Violence Victimization among Latino Adolescents.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Kast, Nicole Rebecca; Eisenberg, Marla E; Sieving, Renee E</p> <p>2016-06-01</p> <p>Dating violence among U.S. adolescents is a substantial concern. Previous research indicates that Latino youth are at increased risk of dating violence victimization. This secondary data analysis examined the prevalence of physical and sexual dating violence victimization among subgroups of Latino adolescents and associations of parent communication, parent caring, and dating violence victimization using data from the 2010 Minnesota Student Survey (N = 4,814). Parallel analyses were conducted for Latino-only and multiple-race Latino adolescents, stratified by gender. Multivariate logistic regression models tested associations between race/ethnicity, parent communication, perceived parent caring, and adolescent dating violence experiences. Overall, 7.2% to 16.2% of Latinos reported physical or sexual dating violence. Both types of dating violence were more prevalent among multiple-race Latinos than among Latino-only adolescents, with prevalence rates highest among multiple-race Latino females (19.8% and 19.7% for physical and sexual dating violence victimization, respectively). In multivariate models, perceived parent caring was the most important protective factor against physical and sexual dating violence among males and females. High levels of mother and father communication were associated with less physical violence victimization among males and females and with less sexual violence victimization among females. Results highlight the importance of parent communication and parent caring as buffers against dating violence victimization for Latino youth. These findings indicate potential for preventive interventions with Latino adolescents targeting family connectedness to address dating violence victimization. © The Author(s) 2015.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19800030127&hterms=texas+tornado&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dtexas%2Btornado','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19800030127&hterms=texas+tornado&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D10%26Ntt%3Dtexas%2Btornado"><span>NASA's participation in the AVE-SESAME '79 program</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Hill, K.; Turner, R. E.; Wilson, G. S.</p> <p>1979-01-01</p> <p>NASA's Marshall Space Flight Center participated with its AVE (Atmospheric Variability Experiment) in a large interagency mesoscale and severe storms experiment identified herein as AVE-SESAME '79 (Atmospheric Variability Experiment-Severe Environmental Storms and Mesoscale Experiment 1979). A primary objective of NASA was to support an effort to acquire carefully edited sets of rawinsonde data during selected severe weather events for use in correlative and diagnostic studies with satellite and radar data obtained at approximately the same times. Data were acquired during six individual 24-h experiments on both the regional and storm scales over a network in the central United States that utilized approximately 20 supplemental rawinsonde sites meshed among 23 standard National Weather Service sites. Included among the six experiments are data obtained between 1200 GMT on April 10 and 1200 GMT on April 11, encompassing the formation and development period for the tornado-producing systems that devastated Wichita Falls, Texas, and other sections of Oklahoma and Texas. The other dates for which data sets are available are April 19-20 and 25-26, May 9-10 and 20-21, and June 7-8, 1979.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70184225','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70184225"><span>Landsat-8: Status and on-orbit performance</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Markham, Brian L; Barsi, Julia A.; Morfitt, Ron; Choate, Michael J.; Montanaro, Matthew; Arvidson, Terry; Irons, James R.</p> <p>2015-01-01</p> <p>Landsat 8 and its two Earth imaging sensors, the Operational Land Imager (OLI) and Thermal Infrared Sensor (TIRS) have been operating on-orbit for 2 ½ years. Landsat 8 has been acquiring substantially more images than initially planned, typically around 700 scenes per day versus a 400 scenes per day requirement, acquiring nearly all land scenes. Both the TIRS and OLI instruments are exceeding their SNR requirements by at least a factor of 2 and are very stable, degrading by at most 1% in responsivity over the mission to date. Both instruments have 100% operable detectors covering their cross track field of view using the redundant detectors as necessary. The geometric performance is excellent, meeting or exceeding all performance requirements. One anomaly occurred with the TIRS Scene Select Mirror (SSM) encoder that affected its operation, though by switching to the side B electronics, this was fully recovered. The one challenge is with the TIRS stray light, which affects the flat fielding and absolute calibration of the TIRS data. The error introduced is smaller in TIRS band 10. Band 11 should not currently be used in science applications.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/19448317','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/19448317"><span>Role playing games: a methodology to acquire knowledge for integrated wastewater infrastructures management in a river basin scale.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Prat, P; Aulinas, M; Turon, C; Comas, J; Poch, M</p> <p>2009-01-01</p> <p>Current management of sanitation infrastructures (sewer systems, wastewater treatment plant, receiving water, bypasses, deposits, etc) is not fulfilling the objectives of up to date legislation, to achieve a good ecological and chemical status of water bodies through integrated management. These made it necessary to develop new methodologies that help decision makers to improve the management in order to achieve that status. Decision Support Systems (DSS) based on Multi-Agent System (MAS) paradigm are promising tools to improve the integrated management. When all the different agents involved interact, new important knowledge emerges. This knowledge can be used to build better DSS and improve wastewater infrastructures management achieving the objectives planned by legislation. The paper describes a methodology to acquire this knowledge through a Role Playing Game (RPG). First of all there is an introduction about the wastewater problems, a definition of RPG, and the relation between RPG and MAS. Then it is explained how the RPG was built with two examples of game sessions and results. The paper finishes with a discussion about the uses of this methodology and future work.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2623810','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2623810"><span>Prevention and treatment of human immunodeficiency virus/acquired immunodeficiency syndrome in resource-limited settings.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Hogan, Daniel R.; Salomon, Joshua A.</p> <p>2005-01-01</p> <p>Strategies for confronting the epidemic of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) have included a range of different approaches that focus on prevention and treatment. However, debate persists over what levels of emphasis are appropriate for the different components of the global response. This paper presents an overview of this debate and briefly summarizes the evidence on a range of interventions designed to prevent the spread of HIV infection, paying particular attention to voluntary counselling and testing, treatment for sexually transmitted infections and prevention of mother-to-child transmission. We also review the experience with antiretroviral therapy to date in terms of response rates and survival rates, adherence, drug resistance, behavioural change and epidemiological impact. Although various studies have identified strategies with proven effectiveness in reducing the risks of HIV infection and AIDS mortality, considerable uncertainties remain. Successful integration of treatment and prevention of HIV/AIDS will require a balanced approach and rigorous monitoring of the impact of programmes in terms of both individual and population outcomes. PMID:15744406</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://images.nasa.gov/#/details-GSFC_20171208_Archive_e001045.html','SCIGOVIMAGE-NASA'); return false;" href="https://images.nasa.gov/#/details-GSFC_20171208_Archive_e001045.html"><span>Terminator View of Mercury</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://images.nasa.gov/">NASA Image and Video Library</a></p> <p></p> <p>2014-07-02</p> <p>Date acquired: May 05, 2014 Today's color image features both Mercury's terminator and limb. The terminator is the striking separation of night and day on Mercury. It is seen in this image with the change from dark, on the left of the image, to light. Mercury's limb is also captured, as we can see the edge between sunlit Mercury and space. The MESSENGER spacecraft is the first ever to orbit the planet Mercury, and the spacecraft's seven scientific instruments and radio science investigation are unraveling the history and evolution of the Solar System's innermost planet. During the first two years of orbital operations, MESSENGER acquired over 150,000 images and extensive other data sets. MESSENGER is capable of continuing orbital operations until early 2015. Credit: NASA/Johns Hopkins University Applied Physics Laboratory/Carnegie Institution of Washington NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/25488029','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/25488029"><span>[Community acquired pneumonia in children: Outpatient treatment and prevention].</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Moreno-Pérez, D; Andrés Martín, A; Tagarro García, A; Escribano Montaner, A; Figuerola Mulet, J; García García, J J; Moreno-Galdó, A; Rodrigo Gonzalo de Lliria, C; Ruiz Contreras, J; Saavedra Lozano, J</p> <p>2015-12-01</p> <p>There have been significant changes in community acquired pneumonia (CAP) in children in the last decade. These changes relate to epidemiology and clinical presentation. Resistance to antibiotics is also a changing issue. These all have to be considered when treating CAP. In this document, two of the main Spanish pediatric societies involved in the treatment of CAP in children, propose a consensus concerning therapeutic approach. These societies are the Spanish Society of Paediatric Infectious Diseases and the Spanish Society of Paediatric Chest Diseases. The Advisory Committee on Vaccines of the Spanish Association of Paediatrics (CAV-AEP) has also been involved in the prevention of CAP. An attempt is made to provide up-to-date guidelines to all paediatricians. The first part of the statement presents the approach to ambulatory, previously healthy children. We also review the prevention with currently available vaccines. In a next second part, special situations and complicated forms will be addressed. Copyright © 2014 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3654609','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3654609"><span>Hypervirulent (hypermucoviscous) Klebsiella pneumoniae</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Shon, Alyssa S.; Bajwa, Rajinder P.S.; Russo, Thomas A.</p> <p>2013-01-01</p> <p>A new hypervirulent (hypermucoviscous) variant of Klebsiella pneumoniae has emerged. First described in the Asian Pacific Rim, it now increasingly recognized in Western countries. Defining clinical features are the ability to cause serious, life-threatening community-acquired infection in younger healthy hosts, including liver abscess, pneumonia, meningitis and endophthalmitis and the ability to metastatically spread, an unusual feature for enteric Gram-negative bacilli in the non-immunocompromised. Despite infecting a healthier population, significant morbidity and mortality occurs. Although epidemiologic features are still being defined, colonization, particularly intestinal colonization, appears to be a critical step leading to infection. However the route of entry remains unclear. The majority of cases described to date are in Asians, raising the issue of a genetic predisposition vs. geospecific strain acquisition. The traits that enhance its virulence when compared with “classical” K. pneumoniae are the ability to more efficiently acquire iron and perhaps an increase in capsule production, which confers the hypermucoviscous phenotype. An objective diagnostic test suitable for routine use in the clinical microbiology laboratory is needed. If/when these strains become increasingly resistant to antimicrobials, we will be faced with a frightening clinical scenario. PMID:23302790</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=ls+AND+models&pg=5&id=EJ078151','ERIC'); return false;" href="https://eric.ed.gov/?q=ls+AND+models&pg=5&id=EJ078151"><span>Instructional Aids in Mathematics: Using Models as Instructional Aids</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Johnson, Donovan A.; And Others</p> <p>1973-01-01</p> <p>Models are discussed both as concrete representations of mental constructs and as various manipulative devices. Illustrations of effective model use, suggestions for acquiring models, and lists of models for specific concepts are included. (LS)</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19910023232','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19910023232"><span>Generation of topographic terrain models utilizing synthetic aperture radar and surface level data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Imhoff, Marc L. (Inventor)</p> <p>1991-01-01</p> <p>Topographical terrain models are generated by digitally delineating the boundary of the region under investigation from the data obtained from an airborne synthetic aperture radar image and surface elevation data concurrently acquired either from an airborne instrument or at ground level. A set of coregistered boundary maps thus generated are then digitally combined in three dimensional space with the acquired surface elevation data by means of image processing software stored in a digital computer. The method is particularly applicable for generating terrain models of flooded regions covered entirely or in part by foliage.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19800005335','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19800005335"><span>Large Area Crop Inventory Experiment (LACIE). Evaluation of the LACIE transition year crop calendar model. [Wheat growth in the Great Plains Corridor, North America</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Cheffin, R. E.; Woolley, S. K. (Principal Investigator)</p> <p>1979-01-01</p> <p>The author has identified the following significant results. The estimates of developmental stage dates from the LACIE adjustable crop calendar (ACC) winter wheat model was somewhat more accurate than the historical crop calendar after jointing. The ACC winter wheat model was not so accurate for the Texas Panhandle as it was for the other areas of the USPG-7 because dry soil conditions delayed fall planting in the Panhandle. Since the LACIE ACC winter wheat model does not contain a moisture term and it was started with historical planting dates, lengthy delays in planting mean that the ACC model will probably be started early and will estimate the developmental growth stages to occur too early in the season. The LACIE ACC spring wheat model was also started early in most areas because of late planting due to fields wet from melting snow and rain. The starter model used to estimate spring planting dates was not accurate under these wet soil conditions and tended to predict the developmental stages to occur earlier than the dates observed in the fields.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li class="active"><span>23</span></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_23 --> <div id="page_24" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="461"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/22160838','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/22160838"><span>Youth experiences of family violence and teen dating violence perpetration: cognitive and emotional mediators.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Jouriles, Ernest N; McDonald, Renee; Mueller, Victoria; Grych, John H</p> <p>2012-03-01</p> <p>This article describes a conceptual model of cognitive and emotional processes proposed to mediate the relation between youth exposure to family violence and teen dating violence perpetration. Explicit beliefs about violence, internal knowledge structures, and executive functioning are hypothesized as cognitive mediators, and their potential influences upon one another are described. Theory and research on the role of emotions and emotional processes in the relation between youths' exposure to family violence and teen dating violence perpetration are also reviewed. We present an integrated model that highlights how emotions and emotional processes work in tandem with hypothesized cognitive mediators to predict teen dating violence.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/servlets/purl/1215207','SCIGOV-STC'); return false;" href="https://www.osti.gov/servlets/purl/1215207"><span>Vehicle Infrastructure Cash-Flow Estimation--VICE 2.0; Clean Cities, Energy Efficiency & Renewable Energy (EERE)</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Mitchell, G.</p> <p></p> <p>This presentation discusses the differences between the original Vehicle and Infrastructure Cash-Flow Evaluation (VICE) Model and the revamped version, VICE 2.0. The enhanced tool can now help assess projects to acquire vehicles and infrastructure, or to acquire vehicles only.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2015AGUFM.B53E0610S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2015AGUFM.B53E0610S"><span>Forest abovegroundbiomass mapping using spaceborne stereo imagery acquired by Chinese ZY-3</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sun, G.; Ni, W.; Zhang, Z.; Xiong, C.</p> <p>2015-12-01</p> <p>Besides LiDAR data, another valuable type of data which is also directly sensitive to forest vertical structures and more suitable for regional mapping of forest biomass is the stereo imagery or photogrammetry. Photogrammetry is the traditional technique for deriving terrain elevation. The elevation of the top of a tree canopy can be directly measured from stereo imagery but winter images are required to get the elevation of ground surface because stereo images are acquired by optical sensors which cannot penetrate dense forest canopies with leaf-on condition. Several spaceborne stereoscopic systems with higher spatial resolutions have been launched in the past several years. For example the Chinese satellite Zi Yuan 3 (ZY-3) specifically designed for the collection of stereo imagery with a resolution of 3.6 m for forward and backward views and 2.1 m for the nadir view was launched on January 9, 2012. Our previous studies have demonstrated that the spaceborne stereo imagery acquired in summer has good performance on the description of forest structures. The ground surface elevation could be extracted from spaceborne stereo imagery acquired in winter. This study mainly focused on assessing the mapping of forest biomass through the combination of spaceborne stereo imagery acquired in summer and those in winter. The test sites of this study located at Daxing AnlingMountains areas as shown in Fig.1. The Daxing Anling site is on the south border of boreal forest belonging to frigid-temperate zone coniferous forest vegetation The dominant tree species is Dhurian larch (Larix gmelinii). 10 scenes of ZY-3 stereo images are used in this study. 5 scenes were acquired on March 14,2012 while the other 5 scenes were acquired on September 7, 2012. Their spatial coverage is shown in Fig.2-a. Fig.2-b is the mosaic of nadir images acquired on 09/07/2012 while Fig.2-c is thecorresponding digital surface model (DSM) derived from stereo images acquired on 09/07/2012. Fig.2-d is the difference between the DSM derived from stereo imagery acquired on 09/07/2012 and the digital elevation model (DEM) from stereo imagery acquired on 03/14/2012.The detailed analysis will be given in the final report.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2011AGUFM.B31A0315C','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2011AGUFM.B31A0315C"><span>Assessment of 14C AMS dating of phytoliths as a new paleoenvironmental and archaeological tool</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Corbineau, R.; Alexandre, A. E.; Santos, G. M.; Reyerson, P. E.</p> <p>2011-12-01</p> <p>14C AMS analysis of occluded carbon in phytoliths (phytC) is a promising dating tool for palaeoenvironmental and archaeological studies. In order to assess the accuracy of this method, different tests were recently carried out on large phytolith concentrates of phytC samples extracted from soils and harvested plants, in association with blank samples of SiO2 powder to check the absence of carbon contamination during the treatments. Despite this precaution, 14C values from recent harvested plants were inexplicably old (2 - 8 ka years BP). Nevertheless, we noticed that many chemical extraction protocols that were used did not lead to samples totally free of organic matter. In order to tackle this problem, and as a first step, the efficiency of common extraction protocols from the literature were tested. Samples were analyzed by SEM/EDX in order to assess the purity of the siliceous material following extraction. As a result of these tests, a new extraction protocol combining acid digestion, oxidation and dry ashing to acquire pure samples of phytoliths from harvested plants is proposed. In a second step, modern and well dated archaeological materials (harvested plants grown within a FACE experiment and plant residues from a 17th century French mummy) were analyzed in 14C-AMS. Results should allow either to demonstrate the reliability of 14C-AMS analysis of phytolith occluded carbon as a dating tool or trigger further investigations of possible sources of old occluded carbon in phytoliths if the 14C ages are still older than expected.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/53686','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/53686"><span>Location of irrigated land classified from satellite imagery - High Plains Area, nominal date 1992</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Qi, Sharon L.; Konduris, Alexandria; Litke, David W.; Dupree, Jean</p> <p>2002-01-01</p> <p>Satellite imagery from the Landsat Thematic Mapper (nominal date 1992) was used to classify and map the location of irrigated land overlying the High Plains aquifer. The High Plains aquifer underlies 174,000 square miles in parts of Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming. The U.S. Geological Survey is conducting a water-quality study of the High Plains aquifer as part of the National Water-Quality Assessment Program. To help interpret data and select sites for the study, it is helpful to know the location of irrigated land within the study area. To date, the only information available for the entire area is 20 years old. To update the data on irrigated land, 40 summer and 40 spring images (nominal date 1992) were acquired from the National Land Cover Data set and processed using a band-ratio method (Landsat Thematic Mapper band 4 divided by band 3) to enhance the vegetation signatures. The study area was divided into nine subregions with similar environmental characteristics, and a band-ratio threshold was selected from imagery in each subregion that differentiated the cutoff between irrigated and nonirrigated land. The classified images for each subregion were mosaicked to produce an irrigated-land map for the study area. The total amount of irrigated land classified from the 1992 imagery was 13.1 million acres, or about 12 percent of the total land in the High Plains. This estimate is approximately 1.5 percent greater than the amount of irrigated land reported in the 1992 Census of Agriculture (12.8 millions acres).</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/18665690','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/18665690"><span>Risk models of dating aggression across different adolescent relationships: a developmental psychopathology approach.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Williams, Tricia S; Connolly, Jennifer; Pepler, Debra; Craig, Wendy; Laporte, Lise</p> <p>2008-08-01</p> <p>The present study examined physical dating aggression in different adolescent relationships and assessed linear, threshold, and moderator risk models for recurrent aggressive relationships. The 621 participants (59% girls, 41% boys) were drawn from a 1-year longitudinal survey of Canadian high school youths ranging from Grade 9 through Grade 12. Approximately 13% of participants reported recurrent dating aggression across 2 different relationships. Using peer and dyadic risk factors from Time 1 of the study, the authors confirmed a linear risk model, such that adolescents in 2 different violent relationships had significantly more contextual risk factors than did adolescents in 1 or no violent relationship. Further, structural equation modeling assessing moderation of contextual risk factors indicated that, for adolescents with high acceptance of dating aggression, peer aggression and delinquency significantly predicted recurrent aggression in a new relationship. In comparison, for adolescents with low acceptance of dating aggression, negative relationship characteristics significantly predicted recurrent aggression. Acceptance did not moderate concurrent associations between risk factors and aggression in 1 relationship. Results support a developmental psychopathological approach to the understanding of recurrent aggression and its associated risk factors. Copyright 2008 APA, all rights reserved.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2893203','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2893203"><span>Pandemic (H1N1) 2009 Influenza Community Transmission Was Established in One Australian State When the Virus Was First Identified in North America</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Kelly, Heath A.; Mercer, Geoff N.; Fielding, James E.; Dowse, Gary K.; Glass, Kathryn; Carcione, Dale; Grant, Kristina A.; Effler, Paul V.; Lester, Rosemary A.</p> <p>2010-01-01</p> <p>Background In mid-June 2009 the State of Victoria in Australia appeared to have the highest notification rate of pandemic (H1N1) 2009 influenza in the world. We hypothesise that this was because community transmission of pandemic influenza was already well established in Victoria at the time testing for the novel virus commenced. In contrast, this was not true for the pandemic in other parts of Australia, including Western Australia (WA). Methods We used data from detailed case follow-up of patients with confirmed infection in Victoria and WA to demonstrate the difference in the pandemic curve in two Australian states on opposite sides of the continent. We modelled the pandemic in both states, using a susceptible-infected-removed model with Bayesian inference accounting for imported cases. Results Epidemic transmission occurred earlier in Victoria and later in WA. Only 5% of the first 100 Victorian cases were not locally acquired and three of these were brothers in one family. By contrast, 53% of the first 102 cases in WA were associated with importation from Victoria. Using plausible model input data, estimation of the effective reproductive number for the Victorian epidemic required us to invoke an earlier date for commencement of transmission to explain the observed data. This was not required in modelling the epidemic in WA. Conclusion Strong circumstantial evidence, supported by modelling, suggests community transmission of pandemic influenza was well established in Victoria, but not in WA, at the time testing for the novel virus commenced in Australia. The virus is likely to have entered Victoria and already become established around the time it was first identified in the US and Mexico. PMID:20596536</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/pages/biblio/1424080-application-radiochronometers-uranium-certified-reference-materials','SCIGOV-DOEP'); return false;" href="https://www.osti.gov/pages/biblio/1424080-application-radiochronometers-uranium-certified-reference-materials"><span>Application of the 226Ra– 230Th– 234U and 227Ac– 231Pa– 235U radiochronometers to uranium certified reference materials</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/pages">DOE PAGES</a></p> <p>Rolison, John M.; Treinen, Kerri C.; McHugh, Kelly C.; ...</p> <p>2017-11-06</p> <p>Uranium certified reference materials (CRM) issued by New Brunswick Laboratory were subjected to dating using four independent uranium-series radiochronometers. In all cases, there was acceptable agreement between the model ages calculated using the 231Pa– 235U, 230Th– 234U, 227Ac– 235U or 226Ra– 234U radiochronometers and either the certified 230Th– 234U model date (CRM 125-A and CRM U630), or the known purification date (CRM U050 and CRM U100). Finally, the agreement between the four independent radiochronometers establishes these uranium certified reference materials as ideal informal standards for validating dating techniques utilized in nuclear forensic investigations in the absence of standards with certifiedmore » model ages for multiple radiochronometers.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/1424080-application-radiochronometers-uranium-certified-reference-materials','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/1424080-application-radiochronometers-uranium-certified-reference-materials"><span>Application of the 226Ra– 230Th– 234U and 227Ac– 231Pa– 235U radiochronometers to uranium certified reference materials</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Rolison, John M.; Treinen, Kerri C.; McHugh, Kelly C.</p> <p></p> <p>Uranium certified reference materials (CRM) issued by New Brunswick Laboratory were subjected to dating using four independent uranium-series radiochronometers. In all cases, there was acceptable agreement between the model ages calculated using the 231Pa– 235U, 230Th– 234U, 227Ac– 235U or 226Ra– 234U radiochronometers and either the certified 230Th– 234U model date (CRM 125-A and CRM U630), or the known purification date (CRM U050 and CRM U100). Finally, the agreement between the four independent radiochronometers establishes these uranium certified reference materials as ideal informal standards for validating dating techniques utilized in nuclear forensic investigations in the absence of standards with certifiedmore » model ages for multiple radiochronometers.« less</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5912149','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5912149"><span>Prediction of Cancer Incidence and Mortality in Korea, 2018</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Jung, Kyu-Won; Won, Young-Joo; Kong, Hyun-Joo; Lee, Eun Sook</p> <p>2018-01-01</p> <p>Purpose This study aimed to report on cancer incidence and mortality for the year 2018 to estimate Korea’s current cancer burden. Materials and Methods Cancer incidence data from 1999 to 2015 were obtained from the Korea National Cancer Incidence Database, and cancer mortality data from 1993 to 2016 were acquired from Statistics Korea. Cancer incidence and mortality were projected by fitting a linear regression model to observed age-specific cancer rates against observed years, then multiplying the projected age-specific rates by the age-specific population. The Joinpoint regression model was used to determine at which year the linear trend changed significantly, we only used the data of the latest trend. Results A total of 204,909 new cancer cases and 82,155 cancer deaths are expected to occur in Korea in 2018. The most common cancer sites were lung, followed by stomach, colorectal, breast and liver. These five cancers represent half of the overall burden of cancer in Korea. For mortality, the most common sites were lung cancer, followed by liver, colorectal, stomach and pancreas. Conclusion The incidence rate of all cancer in Korea are estimated to decrease gradually, mainly due to decrease of thyroid cancer. These up-to-date estimates of the cancer burden in Korea could be an important resource for planning and evaluation of cancer-control programs. PMID:29566480</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016JARS...10d6021B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016JARS...10d6021B"><span>Toward an automated low-cost three-dimensional crop surface monitoring system using oblique stereo imagery from consumer-grade smart cameras</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Brocks, Sebastian; Bendig, Juliane; Bareth, Georg</p> <p>2016-10-01</p> <p>Crop surface models (CSMs) representing plant height above ground level are a useful tool for monitoring in-field crop growth variability and enabling precision agriculture applications. A semiautomated system for generating CSMs was implemented. It combines an Android application running on a set of smart cameras for image acquisition and transmission and a set of Python scripts automating the structure-from-motion (SfM) software package Agisoft Photoscan and ArcGIS. Only ground-control-point (GCP) marking was performed manually. This system was set up on a barley field experiment with nine different barley cultivars in the growing period of 2014. Images were acquired three times a day for a period of two months. CSMs were successfully generated for 95 out of 98 acquisitions between May 2 and June 30. The best linear regressions of the CSM-derived plot-wise averaged plant-heights compared to manual plant height measurements taken at four dates resulted in a coefficient of determination R2 of 0.87 and a root-mean-square error (RMSE) of 0.08 m, with Willmott's refined index of model performance dr equaling 0.78. In total, 103 mean plot heights were used in the regression based on the noon acquisition time. The presented system succeeded in semiautomatedly monitoring crop height on a plot scale to field scale.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2013ISPAn.II5b.265S','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2013ISPAn.II5b.265S"><span>Automatic registration of Iphone images to LASER point clouds of the urban structures using shape features</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Sirmacek, B.; Lindenbergh, R. C.; Menenti, M.</p> <p>2013-10-01</p> <p>Fusion of 3D airborne laser (LIDAR) data and terrestrial optical imagery can be applied in 3D urban modeling and model up-dating. The most challenging aspect of the fusion procedure is registering the terrestrial optical images on the LIDAR point clouds. In this article, we propose an approach for registering these two different data from different sensor sources. As we use iPhone camera images which are taken in front of the interested urban structure by the application user and the high resolution LIDAR point clouds of the acquired by an airborne laser sensor. After finding the photo capturing position and orientation from the iPhone photograph metafile, we automatically select the area of interest in the point cloud and transform it into a range image which has only grayscale intensity levels according to the distance from the image acquisition position. We benefit from local features for registering the iPhone image to the generated range image. In this article, we have applied the registration process based on local feature extraction and graph matching. Finally, the registration result is used for facade texture mapping on the 3D building surface mesh which is generated from the LIDAR point cloud. Our experimental results indicate possible usage of the proposed algorithm framework for 3D urban map updating and enhancing purposes.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2946629','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2946629"><span>The Acquired Preparedness Model of Risk for Bulimic Symptom Development</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Combs, Jessica L.; Smith, Gregory T.; Flory, Kate; Simmons, Jean R.; Hill, Kelly K.</p> <p>2010-01-01</p> <p>The authors applied person-environment transaction theory to test the acquired preparedness model of eating disorder risk. The model holds that (a) middle school girls high in the trait of ineffectiveness are differentially prepared to acquire high risk expectancies for reinforcement from dieting/thinness; (b) those expectancies predict subsequent binge eating and purging; and (c) the influence of the disposition of ineffectiveness on binge eating and purging is mediated by dieting/thinness expectancies. In a three-wave longitudinal study of 394 middle school girls, they found support for the model. Seventh grade girls’ scores on ineffectiveness predicted their subsequent endorsement of high risk dieting/thinness expectancies, which in turn predicted subsequent increases in binge eating and purging. Statistical tests of mediation supported the hypothesis that the prospective relation between ineffectiveness and binge eating was mediated by dieting/thinness expectancies, as was the prospective relation between ineffectiveness and purging. This application of a basic science theory to eating disorder risk appears fruitful, and the findings suggest the importance of early interventions that address both disposition and learning. PMID:20853933</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017EGUGA..19.5137M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017EGUGA..19.5137M"><span>Improving age-depth models using sedimentary proxies for accumulation rates in fluvio-lacustrine deposits</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Minderhoud, Philip S. J.; Cohen, Kim M.; Toonen, Willem. H. J.; Erkens, Gilles; Hoek, Wim Z.</p> <p>2017-04-01</p> <p>Lacustrine fills, including those of oxbow lakes in river floodplains, often hold valuable sedimentary and biological proxy records of palaeo-environmental change. Precise dating of accumulated sediments at levels throughout these records is crucial for interpretation and correlation of (proxy) data existing within the fills. Typically, dates are gathered from multiple sampled levels and their results are combined in age-depth models to estimate the ages of events identified between the datings. In this paper, a method of age-depth modelling is presented that varies the vertical accumulation rate of the lake fill based on continuous sedimentary data. In between Bayesian calibrated radiocarbon dates, this produces a modified non-linear age-depth relation based on sedimentology rather than linear or spline interpolation. The method is showcased on a core of an infilled palaeomeander at the floodplain edge of the river Rhine near Rheinberg (Germany). The sequence spans from 4.7 to 2.9 ka cal BP and consists of 5.5 meters of laminated lacustrine, organo-clastic mud, covered by 1 meter of peaty clay. Four radiocarbon dates provide direct dating control, mapping and dating in the wider surroundings provide additional control. The laminated, organo-clastic facies of the oxbow fill contains a record of nearby fluvial-geomorphological activity, including meander reconfiguration events and passage of rare large floods, recognized as fluctuations in coarseness and amount of allochthonous clastic sediment input. Continuous along-core sampling and measurement of loss-on-ignition (LOI) provided a fast way of expressing the variation in clastic sedimentation influx from the nearby river versus autochthonous organic deposition derived from biogenic production in the lake itself. This low-cost sedimentary proxy data feeds into the age-depth modelling. The sedimentology-modelled age-depth relation (re)produces the distinct lithological boundaries in the fill as marked changes in sedimentation rate. Especially the organo-clastic muddy facies subdivides in centennial intervals of relative faster and slower accumulation. For such intervals, sedimentation rates are produced that deviate 10 to 20% from that in simpler stepped linear age-models. For irregularly laminated muddy intervals of the oxbow fill - from which meaningful sampling for radiocarbon dating is more difficult than from peaty or slowly accumulating organic lake sediments - supplementing spotty radiocarbon sampling with continuous sedimentary proxy data creates more realistic age-depth modelling results.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017GeCoA.218..308A','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017GeCoA.218..308A"><span>Empirical constraints on the effects of radiation damage on helium diffusion in zircon</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Anderson, Alyssa J.; Hodges, Kip V.; van Soest, Matthijs C.</p> <p>2017-12-01</p> <p>In this study, we empirically evaluate the impact of radiation damage on zircon (U-Th)/He closure temperatures for a suite of zircon crystals from the slowly cooled McClure Mountain syenite of south-central Colorado, USA. We present new zircon, titanite, and apatite conventional (U-Th)/He dates, zircon laser ablation (U-Th)/He and U-Pb dates, and zircon Raman spectra for crystals from the syenite. Titanite and apatite (U-Th)/He dates range from 447 to 523 Ma and 88.0 to 138.9 Ma, respectively, and display no clear correlation between (U-Th)/He date and effective uranium concentration. Conventional zircon (U-Th)/He dates range from 230.3 to 474 Ma, while laser ablation zircon (U-Th)/He dates show even greater dispersion, ranging from 5.31 to 520 Ma. Dates from both zircon (U-Th)/He datasets decrease with increasing alpha dose, indicating that most of the dispersion can be attributed to radiation damage. Alpha dose values for the dated zircon crystals range from effectively zero to 2.15 × 1019 α /g, spanning the complete damage spectrum. We use an independently constrained thermal model to empirically assign a closure temperature to each dated zircon grain. If we assume that this thermal model is robust, the zircon radiation damage accumulation and annealing model of Guenthner et al. (2013) does not accurately predict closure temperatures for many of the analyzed zircon crystals. Raman maps of the zircons dated by laser ablation document complex radiation damage zoning, sometimes revealing crystalline zones in grains with alpha dose values suggestive of amorphous material. Such zoning likely resulted in heterogeneous intra-crystalline helium diffusion and may help explain some of the discrepancies between our empirical findings and the Guenthner et al. (2013) model predictions. Because U-Th zoning is a common feature in zircon, radiation damage zoning is likely to be a concern for most ancient, slowly cooled zircon (U-Th)/He datasets. Whenever possible, multiple mineral-isotopic systems should be employed to add additional, independent constraints to a sample's thermal history.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2010PMB....55.4755M','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2010PMB....55.4755M"><span>Combining variational and model-based techniques to register PET and MR images in hand osteoarthritis</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Magee, Derek; Tanner, Steven F.; Waller, Michael; Tan, Ai Lyn; McGonagle, Dennis; Jeavons, Alan P.</p> <p>2010-08-01</p> <p>Co-registration of clinical images acquired using different imaging modalities and equipment is finding increasing use in patient studies. Here we present a method for registering high-resolution positron emission tomography (PET) data of the hand acquired using high-density avalanche chambers with magnetic resonance (MR) images of the finger obtained using a 'microscopy coil'. This allows the identification of the anatomical location of the PET radiotracer and thereby locates areas of active bone metabolism/'turnover'. Image fusion involving data acquired from the hand is demanding because rigid-body transformations cannot be employed to accurately register the images. The non-rigid registration technique that has been implemented in this study uses a variational approach to maximize the mutual information between images acquired using these different imaging modalities. A piecewise model of the fingers is employed to ensure that the methodology is robust and that it generates an accurate registration. Evaluation of the accuracy of the technique is tested using both synthetic data and PET and MR images acquired from patients with osteoarthritis. The method outperforms some established non-rigid registration techniques and results in a mean registration error that is less than approximately 1.5 mm in the vicinity of the finger joints.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=Partner+AND+Preferences&pg=5&id=EJ534602','ERIC'); return false;" href="https://eric.ed.gov/?q=Partner+AND+Preferences&pg=5&id=EJ534602"><span>Adolescents' Age Preferences for Dating Partners: Support for an Evolutionary Model of Life-History Strategies.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kenrick, Douglas T.; And Others</p> <p>1996-01-01</p> <p>Explored sex differences in adolescent preference for older versus younger mates. Found that teenage males were willing to date females of a wide age range, whereas teenage females prefer dating males from their own age to several years older. Data suggested viewing development of sex differences in dating partner preference from the perspective…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2005SPIE.5784..216F','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2005SPIE.5784..216F"><span>Time limited field of regard search</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Flug, Eric; Maurer, Tana; Nguyen, Oanh-Tho</p> <p>2005-05-01</p> <p>Recent work by the US Army RDECOM CERDEC Night Vision and Electronic Sensors Directorate (NVESD) has led to the Time-Limited Search (TLS) model, which has given new formulations for the field of view (FOV) search times. The next step in the evaluation of the overall search model (ACQUIRE) is to apply these parameters to the field of regard (FOR) model. Human perception experiments were conducted using synthetic imagery developed at NVESD. The experiments were competitive player-on-player search tests with the intention of imposing realistic time constraints on the observers. FOR detection probabilities, search times, and false alarm data are analyzed and compared to predictions using both the TLS model and ACQUIRE.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/1990GeoRL..17.1593L','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/1990GeoRL..17.1593L"><span>Background magnetic spectra - Approximately 10 to the -5th to approximately 10 to the 5th Hz</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Lanzerotti, L. J.; Maclennan, C. G.; Fraser-Smith, A. C.</p> <p>1990-09-01</p> <p>The determination of the amplitude and functional form of the geomagnetic fluctuations measured at the Arrival Heights area of the Hut Point Peninsula on Ross Island in June 1986 is presented. The frequency range covered is from approximately 10 to the -5th to approximately 10 to the 5th Hz, with a gap between 0.1 and 10 Hz due to instrumentation limitations. In spite of this gap, it is thought that these magnetic fluctuation spectra, obtained from data acquired simultaneously with two instruments, cover the broadest frequency range to date. Schematic spectra derived from the data obtained are provided.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.osti.gov/biblio/7067251-fundamentals-scada-automated-meter-reading','SCIGOV-STC'); return false;" href="https://www.osti.gov/biblio/7067251-fundamentals-scada-automated-meter-reading"><span>Fundamentals of SCADA and automated meter reading</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.osti.gov/search">DOE Office of Scientific and Technical Information (OSTI.GOV)</a></p> <p>Kwok, A.</p> <p>1992-02-01</p> <p>This paper discusses SCADA systems allow users to control and acquire data from remote facilities such as compressors, pressure-regulating stations, control valves and measurement stations. In general, a SCADA system performs functions in sequential control, continuous control, supervisory setpoint control and data acquisitions. AMR systems allow users to obtain up-to-date information on their gas demand. When AMR was in its infancy, equipment was designed only to read and record gas consumption values. The basic function of an early AMR system was to read gas volume at a fixed interval and record the data in its memory until it communicated withmore » a central receiving facility.« less</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li class="active"><span>24</span></li> <li><a href="#" onclick='return showDiv("page_25");'>25</a></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_24 --> <div id="page_25" class="hiddenDiv"> <div class="row"> <div class="col-sm-12"> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div> </div> <div class="row"> <div class="col-sm-12"> <ol class="result-class" start="481"> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/26494380','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/26494380"><span>Value-driven attentional capture in the auditory domain.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Anderson, Brian A</p> <p>2016-01-01</p> <p>It is now well established that the visual attention system is shaped by reward learning. When visual features are associated with a reward outcome, they acquire high priority and can automatically capture visual attention. To date, evidence for value-driven attentional capture has been limited entirely to the visual system. In the present study, I demonstrate that previously reward-associated sounds also capture attention, interfering more strongly with the performance of a visual task. This finding suggests that value-driven attention reflects a broad principle of information processing that can be extended to other sensory modalities and that value-driven attention can bias cross-modal stimulus competition.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://hdl.handle.net/2060/19890003230','NASA-TRS'); return false;" href="http://hdl.handle.net/2060/19890003230"><span>Indian LSSC (Large Space Simulation Chamber) facility</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Brar, A. S.; Prasadarao, V. S.; Gambhir, R. D.; Chandramouli, M.</p> <p>1988-01-01</p> <p>The Indian Space Agency has undertaken a major project to acquire in-house capability for thermal and vacuum testing of large satellites. This Large Space Simulation Chamber (LSSC) facility will be located in Bangalore and is to be operational in 1989. The facility is capable of providing 4 meter diameter solar simulation with provision to expand to 4.5 meter diameter at a later date. With such provisions as controlled variations of shroud temperatures and availability of infrared equipment as alternative sources of thermal radiation, this facility will be amongst the finest anywhere. The major design concept and major aspects of the LSSC facility are presented here.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://pubs.er.usgs.gov/publication/70042401','USGSPUBS'); return false;" href="https://pubs.er.usgs.gov/publication/70042401"><span>Archiving strategy for USGS EROS center and our future direction</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://pubs.er.usgs.gov/pubs/index.jsp?view=adv">USGS Publications Warehouse</a></p> <p>Faundeen, John L.</p> <p>2010-01-01</p> <p>The U. S. Geological Survey's Earth Resources Observation and Science Center has the responsibility to acquire, manage, and preserve our Nation's land observations. These records are obtained primarily from airplanes and satellites dating back to the 1930s. The ability to compare landscapes from the past with current information enables change analysis at local and global scales. With new observations added daily, the records management challenges are daunting, involving petabytes of electronic data and tens of thousands of rolls of analog film. This paper focuses upon the appraisal and preservation functions employed to ensure that these records are available for current and future generations.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/28662712','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/28662712"><span>11q deletion in neuroblastoma: a review of biological and clinical implications.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Mlakar, Vid; Jurkovic Mlakar, Simona; Lopez, Gonzalo; Maris, John M; Ansari, Marc; Gumy-Pause, Fabienne</p> <p>2017-06-29</p> <p>Deletion of the long arm of chromosome 11 (11q deletion) is one of the most frequent events that occur during the development of aggressive neuroblastoma. Clinically, 11q deletion is associated with higher disease stage and decreased survival probability. During the last 25 years, extensive efforts have been invested to identify the precise frequency of 11q aberrations in neuroblastoma, the recurrently involved genes, and to understand the molecular mechanisms of 11q deletion, but definitive answers are still unclear. In this review, it is our intent to compile and review the evidence acquired to date on 11q deletion in neuroblastoma.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://images.nasa.gov/#/details-PIA21284.html','SCIGOVIMAGE-NASA'); return false;" href="https://images.nasa.gov/#/details-PIA21284.html"><span>Lanzarote, Canary Islands</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://images.nasa.gov/">NASA Image and Video Library</a></p> <p></p> <p>2017-01-06</p> <p>Lanzarote is the easternmost of the Canary Islands, 125 km off the coast of Africa, and is the fourth largest of the archipelago, with an area of 846 square kilometers. Like all of the Canary Islands, its volcanic origin dates to about 15 million years ago. The largest historic eruption occurred in the 1730s. The island was first recorded by Pliny the Elder, though it may have been originally settled by the Phoenicians (Wikipedia). The image was acquired 12 March 2015, covers an area of 50.5 by 55.1 km, and is located near 29 degrees north, 13.6 degrees west. http://photojournal.jpl.nasa.gov/catalog/PIA21284</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15887558','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15887558"><span>Landcover classification in MRF context using Dempster-Shafer fusion for multisensor imagery.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Sarkar, Anjan; Banerjee, Anjan; Banerjee, Nilanjan; Brahma, Siddhartha; Kartikeyan, B; Chakraborty, Manab; Majumder, K L</p> <p>2005-05-01</p> <p>This work deals with multisensor data fusion to obtain landcover classification. The role of feature-level fusion using the Dempster-Shafer rule and that of data-level fusion in the MRF context is studied in this paper to obtain an optimally segmented image. Subsequently, segments are validated and classification accuracy for the test data is evaluated. Two examples of data fusion of optical images and a synthetic aperture radar image are presented, each set having been acquired on different dates. Classification accuracies of the technique proposed are compared with those of some recent techniques in literature for the same image data.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://ntrs.nasa.gov/search.jsp?R=19830056406&hterms=Corn&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DCorn','NASA-TRS'); return false;" href="https://ntrs.nasa.gov/search.jsp?R=19830056406&hterms=Corn&qs=Ntx%3Dmode%2Bmatchall%26Ntk%3DAll%26N%3D0%26No%3D60%26Ntt%3DCorn"><span>Identification of corn fields using multidate radar data</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://ntrs.nasa.gov/search.jsp">NASA Technical Reports Server (NTRS)</a></p> <p>Shanmugan, K. S.; Ulaby, F. T.; Narayanan, V.; Dobson, C.</p> <p>1983-01-01</p> <p>Airborne C- and L-band radar data acquired over a test site in western kansas were analyzed to determine corn-field identification accuracies obtainable using single-channel, multichannel, and multidate radar data. An automated pattern-recognition procedure was used to classify 144 fields into three categories: corn, pasture land, and bare soil (including wheat stubble and fallow). Corn fields were identified with accuracies ranging from 85 percent for single channel, single-date data to 100 percent for single-channel, multidate data. The effects of radar parameters such as frequency, polarization, and look angle as well as the effects of soil moisture on the classification accuracy are also presented.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/21199635','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/21199635"><span>Laugier-Hunziker syndrome: A case report and review of the literature.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Rangwala, Sophia; Doherty, Christy B; Katta, Rajani</p> <p>2010-12-15</p> <p>Laugier-Hunziker syndrome (LHS) is a rare acquired disorder characterized by diffuse macular hyperpigmentation of the oral mucosa and, at times, longitudinal melanonychia. Although LHS is considered a benign disease with no systemic manifestations or malignant potential, it is important to rule out other mucocutaneous pigmentary disorders that do require medical management. Prompt clinical recognition also averts the need for excessive and invasive procedures and treatments. To date, only four cases have been reported in the United States. We present a 77-year-old man who had clinical features typical of LHS and we then provide a review of the literature on LHS and its mimickers.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4196373','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4196373"><span>Issues in the Perception of AIDS Risk and Risk Reduction Activities by Black and Hispanic/Latina Women</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Mays, Vickie M.; Cochran, Susan D.</p> <p>2014-01-01</p> <p>Although to date most cases of Acquired Immunodeficiency Syndrome (AIDS) have occurred among men, AIDS poses a serious threat for Black and Latina women, particularly for those who are poor and live in geographic areas of higher AIDS incidence. Yet many may not perceive themselves to be at risk from what has generally been portrayed as a “White gay disease.” This article examines patterns of AIDS infection in women and factors associated with risk perception and behavior change. In doing so, the influence of ethnic minority culture on the behavior of individual women is explored. PMID:3214007</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/15465689','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/15465689"><span>The effect of family and peer communication on college students' communication with dating partners about HIV and AIDS.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Powell, Heather L; Segrin, Chris</p> <p>2004-01-01</p> <p>As family and peers are primary socializing agents in the lives of young adults, a social learning based model of communication about HIV/AIDS among dating partners was developed and tested, examining the role of interactions with family and peers in this type of communication. Specifically, the model describes relationships between general communication, communication about sexuality, and communication about HIV/AIDS with parents, peers, and dating partners. Participants were 153 young adult couples who completed measures of their communication practices, as well as their communication with family and peers. Communication practices in the family of origin appear to influence both general communication and communication about HIV/AIDS with dating partners. Communication practices with peers influenced general communication, communication about sexuality, and communication about HIV/AIDS with dating partners. Participants and their dating partners exhibited relative agreement about their general communication practices and their communication about HIV/AIDS, but showed less agreement in reports of their communication about sexuality. Implications for understanding the role of family and peer interactions in communication about HIV/AIDS with dating partners are discussed.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3686210','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3686210"><span>High-resolution prediction of leaf onset date in Japan in the 21st century under the IPCC A1B scenario</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Hadano, Mayumi; Nasahara, Kenlo Nishida; Motohka, Takeshi; Noda, Hibiki Muraoka; Murakami, Kazutaka; Hosaka, Masahiro</p> <p>2013-01-01</p> <p>Reports indicate that leaf onset (leaf flush) of deciduous trees in cool-temperate ecosystems is occurring earlier in the spring in response to global warming. In this study, we created two types of phenology models, one driven only by warmth (spring warming [SW] model) and another driven by both warmth and winter chilling (parallel chill [PC] model), to predict such phenomena in the Japanese Islands at high spatial resolution (500 m). We calibrated these models using leaf onset dates derived from satellite data (Terra/MODIS) and in situ temperature data derived from a dense network of ground stations Automated Meteorological Data Acquisition System. We ran the model using future climate predictions created by the Japanese Meteorological Agency's MRI-AGCM3.1S model. In comparison to the first decade of the 2000s, our results predict that the date of leaf onset in the 2030s will advance by an average of 12 days under the SW model and 7 days under the PC model throughout the study area. The date of onset in the 2090s will advance by 26 days under the SW model and by 15 days under the PC model. The greatest impact will occur on Hokkaido (the northernmost island) and in the central mountains. PMID:23789086</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2016APS..MARB41002B','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2016APS..MARB41002B"><span>Dynamics of adaptive immunity against phage in bacterial populations</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Bradde, Serena; Vucelja, Marija; Tesileanu, Tiberiu; Balasubramanian, Vijay</p> <p></p> <p>The CRISPR (clustered regularly interspaced short palindromic repeats) mechanism allows bacteria to adaptively defend against phages by acquiring short genomic sequences (spacers) that target specific sequences in the viral genome. We propose a population dynamical model where immunity can be both acquired and lost. The model predicts regimes where bacterial and phage populations can co-exist, others where the populations oscillate, and still others where one population is driven to extinction. Our model considers two key parameters: (1) ease of acquisition and (2) spacer effectiveness in conferring immunity. Analytical calculations and numerical simulations show that if spacers differ mainly in ease of acquisition, or if the probability of acquiring them is sufficiently high, bacteria develop a diverse population of spacers. On the other hand, if spacers differ mainly in their effectiveness, their final distribution will be highly peaked, akin to a ``winner-take-all'' scenario, leading to a specialized spacer distribution. Bacteria can interpolate between these limiting behaviors by actively tuning their overall acquisition rate.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('http://adsabs.harvard.edu/abs/2017AcSpe.138...64T','NASAADS'); return false;" href="http://adsabs.harvard.edu/abs/2017AcSpe.138...64T"><span>Detection and correction of laser induced breakdown spectroscopy spectral background based on spline interpolation method</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://adsabs.harvard.edu/abstract_service.html">NASA Astrophysics Data System (ADS)</a></p> <p>Tan, Bing; Huang, Min; Zhu, Qibing; Guo, Ya; Qin, Jianwei</p> <p>2017-12-01</p> <p>Laser-induced breakdown spectroscopy (LIBS) is an analytical technique that has gained increasing attention because of many applications. The production of continuous background in LIBS is inevitable because of factors associated with laser energy, gate width, time delay, and experimental environment. The continuous background significantly influences the analysis of the spectrum. Researchers have proposed several background correction methods, such as polynomial fitting, Lorenz fitting and model-free methods. However, less of them apply these methods in the field of LIBS Technology, particularly in qualitative and quantitative analyses. This study proposes a method based on spline interpolation for detecting and estimating the continuous background spectrum according to its smooth property characteristic. Experiment on the background correction simulation indicated that, the spline interpolation method acquired the largest signal-to-background ratio (SBR) over polynomial fitting, Lorenz fitting and model-free method after background correction. These background correction methods all acquire larger SBR values than that acquired before background correction (The SBR value before background correction is 10.0992, whereas the SBR values after background correction by spline interpolation, polynomial fitting, Lorentz fitting, and model-free methods are 26.9576, 24.6828, 18.9770, and 25.6273 respectively). After adding random noise with different kinds of signal-to-noise ratio to the spectrum, spline interpolation method acquires large SBR value, whereas polynomial fitting and model-free method obtain low SBR values. All of the background correction methods exhibit improved quantitative results of Cu than those acquired before background correction (The linear correlation coefficient value before background correction is 0.9776. Moreover, the linear correlation coefficient values after background correction using spline interpolation, polynomial fitting, Lorentz fitting, and model-free methods are 0.9998, 0.9915, 0.9895, and 0.9940 respectively). The proposed spline interpolation method exhibits better linear correlation and smaller error in the results of the quantitative analysis of Cu compared with polynomial fitting, Lorentz fitting and model-free methods, The simulation and quantitative experimental results show that the spline interpolation method can effectively detect and correct the continuous background.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27155009','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27155009"><span>Biogeographic Dating of Speciation Times Using Paleogeographically Informed Processes.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Landis, Michael J</p> <p>2017-03-01</p> <p>Standard models of molecular evolution cannot estimate absolute speciation times alone, and require external calibrations to do so, such as fossils. Because fossil calibration methods rely on the incomplete fossil record, a great number of nodes in the tree of life cannot be dated precisely. However, many major paleogeographical events are dated, and since biogeographic processes depend on paleogeographical conditions, biogeographic dating may be used as an alternative or complementary method to fossil dating. I demonstrate how a time-stratified biogeographic stochastic process may be used to estimate absolute divergence times by conditioning on dated paleogeographical events. Informed by the current paleogeographical literature, I construct an empirical dispersal graph using 25 areas and 26 epochs for the past 540 Ma of Earth's history. Simulations indicate biogeographic dating performs well so long as paleogeography imposes constraint on biogeographic character evolution. To gauge whether biogeographic dating may be of practical use, I analyzed the well-studied turtle clade (Testudines) to assess how well biogeographic dating fares when compared to fossil-calibrated dating estimates reported in the literature. Fossil-free biogeographic dating estimated the age of the most recent common ancestor of extant turtles to be from the Late Triassic, which is consistent with fossil-based estimates. Dating precision improves further when including a root node fossil calibration. The described model, paleogeographical dispersal graph, and analysis scripts are available for use with RevBayes. © The Author(s) 2016. Published by Oxford University Press, on behalf of the Society of Systematic Biologists. All rights reserved. For Permissions, please email: journals.permissions@oup.com.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5348014','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5348014"><span>Bayesian model of signal rewiring reveals mechanisms of gene dysregulation in acquired drug resistance in breast cancer</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Azad, A. K. M.; Keith, Jonathan M.</p> <p>2017-01-01</p> <p>Small molecule inhibitors, such as lapatinib, are effective against breast cancer in clinical trials, but tumor cells ultimately acquire resistance to the drug. Maintaining sensitization to drug action is essential for durable growth inhibition. Recently, adaptive reprogramming of signaling circuitry has been identified as a major cause of acquired resistance. We developed a computational framework using a Bayesian statistical approach to model signal rewiring in acquired resistance. We used the p1-model to infer potential aberrant gene-pairs with differential posterior probabilities of appearing in resistant-vs-parental networks. Results were obtained using matched gene expression profiles under resistant and parental conditions. Using two lapatinib-treated ErbB2-positive breast cancer cell-lines: SKBR3 and BT474, our method identified similar dysregulated signaling pathways including EGFR-related pathways as well as other receptor-related pathways, many of which were reported previously as compensatory pathways of EGFR-inhibition via signaling cross-talk. A manual literature survey provided strong evidence that aberrant signaling activities in dysregulated pathways are closely related to acquired resistance in EGFR tyrosine kinase inhibitors. Our approach predicted literature-supported dysregulated pathways complementary to both node-centric (SPIA, DAVID, and GATHER) and edge-centric (ESEA and PAGI) methods. Moreover, by proposing a novel pattern of aberrant signaling called V-structures, we observed that genes were dysregulated in resistant-vs-sensitive conditions when they were involved in the switch of dependencies from targeted to bypass signaling events. A literature survey of some important V-structures suggested they play a role in breast cancer metastasis and/or acquired resistance to EGFR-TKIs, where the mRNA changes of TGFBR2, LEF1 and TP53 in resistant-vs-sensitive conditions were related to the dependency switch from targeted to bypass signaling links. Our results suggest many signaling pathway structures are compromised in acquired resistance, and V-structures of aberrant signaling within/among those pathways may provide further insights into the bypass mechanism of targeted inhibition. PMID:28288164</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/23613122','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/23613122"><span>Self-determination and sexual experience in dating relationships.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Brunell, Amy B; Webster, Gregory D</p> <p>2013-07-01</p> <p>The authors propose the Model of Self-Determined Sexual Motivation to examine sexual motivation in dating relationships using a Self-Determination Theory (SDT) framework. This model predicted that sexual need satisfaction would mediate the association between self-determined sexual motives and the outcome variables of psychological well-being and relational quality. Three studies tested this model. Study 1 was a cross-sectional study that investigated sexual motivation in dating relationships. Study 2 was an event-contingent interaction record study that investigated specific sexual interactions over 2 weeks. Study 3 combined event- and interval-contingent methods using a daily diary to examine the model for both partners to enable examination of actor and partner effects. Discussion section focuses on the power of examining SDT in the sexual domain.</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=card+AND+credit&pg=7&id=EJ621101','ERIC'); return false;" href="https://eric.ed.gov/?q=card+AND+credit&pg=7&id=EJ621101"><span>A Cognitive Analysis of Credit Card Acquisition and College Student Financial Development.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Kidwell, Blair; Turrisi, Robert</p> <p>2000-01-01</p> <p>Examines cognitions relevant to credit card decision making in college-aged participants (N=304). Assesses measures of beliefs, attitudes, and behavioral alternatives toward acquiring a credit card. Identifies a multivariate model predicting college student financial development of the attitudes and behavioral tendencies of acquiring a new card.…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://eric.ed.gov/?q=viewing+AND+room&pg=3&id=EJ850192','ERIC'); return false;" href="https://eric.ed.gov/?q=viewing+AND+room&pg=3&id=EJ850192"><span>Words and Maps: Developmental Changes in Mental Models of Spatial Information Acquired from Descriptions and Depictions</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.eric.ed.gov/ERICWebPortal/search/extended.jsp?_pageLabel=advanced">ERIC Educational Resources Information Center</a></p> <p>Uttal, David H.; Fisher, Joan A.; Taylor, Holly A.</p> <p>2006-01-01</p> <p>People acquire spatial information from many sources, including maps, verbal descriptions, and navigating in the environment. The different sources present spatial information in different ways. For example, maps can show many spatial relations simultaneously, but in a description, each spatial relation must be presented sequentially. The present…</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4473327','PMC'); return false;" href="https://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4473327"><span>Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pmc">PubMed Central</a></p> <p>Monsma, David J; Cherba, David M; Eugster, Emily E; Dylewski, Dawna L; Davidson, Paula T; Peterson, Chelsea A; Borgman, Andrew S; Winn, Mary E; Dykema, Karl J; Webb, Craig P; MacKeigan, Jeffrey P; Duesbery, Nicholas S; Nickoloff, Brian J; Monks, Noel R</p> <p>2015-01-01</p> <p>Variable clinical responses, tumor heterogeneity, and drug resistance reduce long-term survival outcomes for metastatic melanoma patients. To guide and accelerate drug development, we characterized tumor responses for five melanoma patient derived xenograft models treated with Vemurafenib. Three BRAFV600E models showed acquired drug resistance, one BRAFV600E model had a complete and durable response, and a BRAFV600V model was expectedly unresponsive. In progressing tumors, a variety of resistance mechanisms to BRAF inhibition were uncovered, including mutant BRAF alternative splicing, NRAS mutation, COT (MAP3K8) overexpression, and increased mutant BRAF gene amplification and copy number. The resistance mechanisms among the patient derived xenograft models were similar to the resistance pathways identified in clinical specimens from patients progressing on BRAF inhibitor therapy. In addition, there was both inter- and intra-patient heterogeneity in resistance mechanisms, accompanied by heterogeneous pERK expression immunostaining profiles. MEK monotherapy of Vemurafenib-resistant tumors caused toxicity and acquired drug resistance. However, tumors were eradicated when Vemurafenib was combined the MEK inhibitor. The diversity of drug responses among the xenograft models; the distinct mechanisms of resistance; and the ability to overcome resistance by the addition of a MEK inhibitor provide a scheduling rationale for clinical trials of next-generation drug combinations. PMID:26101714</p> </li> <li> <p><a target="_blank" rel="noopener noreferrer" onclick="trackOutboundLink('https://www.ncbi.nlm.nih.gov/pubmed/27007698','PUBMED'); return false;" href="https://www.ncbi.nlm.nih.gov/pubmed/27007698"><span>Predicting Risk for Suicide: A Preliminary Examination of Non-Suicidal Self-Injury and the Acquired Capability Construct in a College Sample.</span></a></p> <p><a target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed">PubMed</a></p> <p>Brackman, Emily H; Morris, Blair W; Andover, Margaret S</p> <p>2016-01-01</p> <p>The interpersonal psychological theory of suicide provides a useful framework for considering the relationship between non-suicidal self-injury and suicide. Researchers propose that NSSI increases acquired capability for suicide. We predicted that both NSSI frequency and the IPTS acquired capability construct (decreased fear of death and increased pain tolerance) would separately interact with suicidal ideation to predict suicide attempts. Undergraduate students (N = 113) completed self-report questionnaires, and a subsample (n = 66) also completed a pain sensitivity task. NSSI frequency significantly moderated the association between suicidal ideation and suicide attempts. However, in a separate model, acquired capability did not moderate this relationship. Our understanding of the relationship between suicidal ideation and suicidal behavior can be enhanced by factors associated with NSSI that are distinct from the acquired capability construct.</p> </li> </ol> <div class="pull-right"> <ul class="pagination"> <li><a href="#" onclick='return showDiv("page_1");'>«</a></li> <li><a href="#" onclick='return showDiv("page_21");'>21</a></li> <li><a href="#" onclick='return showDiv("page_22");'>22</a></li> <li><a href="#" onclick='return showDiv("page_23");'>23</a></li> <li><a href="#" onclick='return showDiv("page_24");'>24</a></li> <li class="active"><span>25</span></li> <li><a href="#" onclick='return showDiv("page_25");'>»</a></li> </ul> </div> </div><!-- col-sm-12 --> </div><!-- row --> </div><!-- page_25 --> <div class="footer-extlink text-muted" style="margin-bottom:1rem; text-align:center;">Some links on this page may take you to non-federal websites. Their policies may differ from this site.</div> </div><!-- container --> <a id="backToTop" href="#top"> Top </a> <footer> <nav> <ul class="links"> <li><a href="/sitemap.html">Site Map</a></li> <li><a href="/website-policies.html">Website Policies</a></li> <li><a href="https://www.energy.gov/vulnerability-disclosure-policy" target="_blank">Vulnerability Disclosure Program</a></li> <li><a href="/contact.html">Contact Us</a></li> </ul> </nav> </footer> <script type="text/javascript"><!-- // var lastDiv = ""; function showDiv(divName) { // hide last div if (lastDiv) { document.getElementById(lastDiv).className = "hiddenDiv"; } //if value of the box is not nothing and an object with that name exists, then change the class if (divName && document.getElementById(divName)) { document.getElementById(divName).className = "visibleDiv"; lastDiv = divName; } } //--> </script> <script> /** * Function that tracks a click on an outbound link in Google Analytics. * This function takes a valid URL string as an argument, and uses that URL string * as the event label. */ var trackOutboundLink = function(url,collectionCode) { try { h = window.open(url); setTimeout(function() { ga('send', 'event', 'topic-page-click-through', collectionCode, url); }, 1000); } catch(err){} }; </script> <!-- Google Analytics --> <script> (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','//www.google-analytics.com/analytics.js','ga'); ga('create', 'UA-1122789-34', 'auto'); ga('send', 'pageview'); </script> <!-- End Google Analytics --> <script> showDiv('page_1') </script> </body> </html>