#### Sample records for modeling orifice pulse

1. Development and experimental test of an analytical model of the orifice pulse tube refrigerator

NASA Technical Reports Server (NTRS)

1988-01-01

An analytical model for the orifice pulse tube is developed, in which the system is described in terms of average enthalpy flow with such simplifying assumptions as an ideal gas and sinusoidal pressure variation. Phasor analysis is used to represent temperature, pressure, and mass-flow rate waves in vector form. The model predictions, namely, that the refrigeration power of a pulse-tube refrigerator is proportional to the average pressure, the pulse frequency, the mass-flow ratio, and the square of the dynamic pressure ratio, were verified by experimental measurements. It was found that, as a result of the simplifying assumptions, the magnitudes of the refrigeration power predicted by the model were between three and five times greater than experimental values.

2. Theory of ideal orifice pulse tube refrigerator

David, M.; Maréchal, J.-C.; Simon, Y.; Guilpin, C.

The main purpose of this paper is to explain the operation of the orifice pulse tube refrigerator (OPTR). An analytical model of the ideal OPT has been developed. The mechanism of heat flow at the tube ends is clearly explained as the result of the hysteretic process of the elements of gas entering and leaving the tube. The motion of the buffer gas is deduced by numerical integration and the expected balance equation for the heat flows at the hot and cold exchangers is established. A numerical calculation of the velocity profile along the pulse tube is in good agreement with hot-wire anemometry data. In working conditions, we found, for the gross refrigeration power, < q˙>, theory/experiment ratios as low as 1.2, whereas those previously reported by Storch and Radebaugh were about 3 - 5. The differences between the theory of Radebaugh et al. and our model are following: (1) Radebaugh and co-workers assume small sinusoidal oscillations of the gas pressure in the tube ( ΔP/ P¯ « 1 ) whereas we describe the gas flow in the tube for any time-dependence of the pressure oscillation P( t); (2) In our model, < q˙>, is expressed with a minimum number of independent and controlled parameters relative to the OPT. In a double inlet pulse tube configuration, our test apparatus was able to achieve a 32 K temperature limit.

3. A small, single stage orifice pulse tube cryocooler demonstration

NASA Technical Reports Server (NTRS)

Hendricks, John B.

1990-01-01

This final report summarizes and presents the analytical and experimental progress in the present effort. The principal objective of this effort was the demonstration of a 0.25 Watt, 80 Kelvin orifice pulse tube refrigerator. The experimental apparatus is described. The design of a partially optimized pulse tube refrigerator is included. The refrigerator demonstrates an ultimate temperature of 77 K, has a projected cooling power of 0.18 Watts at 80 K, and has a measured cooling power of 1 Watt at 97 K, with an electrical efficiency of 250 Watts/Watt, much better than previous pulse tube refrigerators. A model of the pulse tube refrigerator that provides estimates of pressure ratio and mass flow within the pulse tube refrigerator, based on component physical characteristics is included. A model of a pulse tube operation based on generalized analysis which is adequate to support local optimization of existing designs is included. A model of regenerator performance based on an analogy to counterflow heat exchangers is included.

4. A pulse-tube refrigerator using variable-resistance orifice

Huang, B. J.; Sun, B. W.

2003-01-01

In the present study, we propose a new design of orifice pulse-tube refrigerator (VROPT) using a variable-resistance valve to replace the conventional orifice. The variable-resistance orifice (VRO) is basically a high-speed solenoidal valve similar to the fuel jet device widely used in automobile engines. By changing the frequency and periods of ON and OFF of the valve through an electronic device, we can change the flow resistance of the VRO. This thus provides a possibility for an OPT to be controlled on-line during operation. From the results obtained in the present study, we have shown that VROPT is able to achieve on-line control by regulating the duty cycle d or frequency fv of the VRO. We also show that VROPT will not loss its thermal performance as compared to conventional OPT.

5. Formation of Single Bubbles from a Submerged Orifice Using Pulsed Ultrasound Waves

Shirota, Minori; Imamura, Tomohiro; Kameda, Masaharu

A new experimental method is presented in which single small gas bubbles are generated in a liquid from a submerged orifice using pulsed ultrasound waves. Pulsed ultrasound waves having a frequency of 15 kHz and a maximum pressure amplitude of approximately 10 kPa are irradiated to a bubble growing from an orifice. Single air bubbles ranging from approximately 0.05 to 0.2 mm in radius are obtained in silicone oil (kinematic viscosity: 1 mm2/s) by using two orifices (0.02 and 0.04 mm in diameter) and by shifting the onset of the detachment-assistance pressure wave. The bubble deformation and detaching processes were visualized and analyzed using high-speed video imaging and direct numerical simulation. Consequently, it is revealed that the bubbles are forced to elongate upward due to the fast oscillatory flow of gas through the orifice, and the elongation causes the bubbles to detach from the orifice. The size of the bubbles at detachment is well estimated by employing a common spherical bubble formation model.

6. Fluid mechanical model of the acoustic impedance of small orifices

NASA Technical Reports Server (NTRS)

Hersh, A. S.; Rogers, T.

1976-01-01

A fluid mechanical model of the acoustic behavior of small orifices is presented which predicts orifice resistance and reactance as a function of incident sound pressure level, frequency, and orifice geometry. Agreement between predicted and measured values is excellent. The model shows the following: (1) The acoustic flow in immediate neighborhood of the orifice can be modeled as a locally spherical flow. Within this near field, the flow is, to a first approximation, unsteady and incompressible. (2) At very low sound pressure levels, the orifice viscous resistance is directly related to the effect of boundary-layer displacement along the walls containing the orifice, and the orifice reactance is directly related to the inertia of the oscillating flow in the neighborhood of the orifice. (3) For large values of the incident acoustic pressure, the impedance is dominated by nonlinear jet-like effects. (4) For low values of the pressure, the resistance and reactance are roughly equal.

7. Method and apparatus for fine tuning an orifice pulse tube refrigerator

DOEpatents

Swift, Gregory W.; Wollan, John J.

2003-12-23

An orifice pulse tube refrigerator uses flow resistance, compliance, and inertance components connected to a pulse tube for establishing a phase relationship between oscillating pressure and oscillating velocity in the pulse tube. A temperature regulating system heats or cools a working gas in at least one of the flow resistance and inertance components. A temperature control system is connected to the temperature regulating system for controlling the temperature of the working gas in the at least one of the flow resistance and inertance components and maintains a control temperature that is indicative of a desired temporal phase relationship.

8. The influence of gas velocity on surface heat pumping for the orifice pulse tube refrigerator

NASA Technical Reports Server (NTRS)

Lee, J. M.; Dill, H. R.

1990-01-01

The basic pulse tube refrigerator produces cooling by a mechanism known as surface heat pumping. Cyclical compression and expansion of a gas within an enclosed tube produces large temperature gradients. The purpose of the tube is to act as 'nodal regenerator'. Heat is stored at node positions along the tube wall and is transported between nodes by moving gas parcels. This process gives rise to refrigeration, with hot temperatures at the closed end and cold temperatures at the open end. Unfortunately, much of the available refrigeration is not realized because the closed end of the basic pulse tube restricts gas movement - gas at the extreme temperatures does not come in contact with the heat exchangers. The orifice pulse tube overcomes this limitation by using a valve and surge volume assembly at the warm, closed end. This allows for a residual gas velocity to remain present during the heat transfer process, thereby permitting more gas to exchange heat at the heat exchangers. This paper describes the pulse tube as a nodal regenerator and the effect residual gas velocity has on the heat transfer mechanism of the orifice pulse tube.

9. The influence of gas velocity on surface heat pumping for the orifice pulse tube refrigerator

Lee, J. M.; Dill, H. R.

The basic pulse tube refrigerator produces cooling by a mechanism known as surface heat pumping. Cyclical compression and expansion of a gas within an enclosed tube produces large temperature gradients. The purpose of the tube is to act as 'nodal regenerator'. Heat is stored at node positions along the tube wall and is transported between nodes by moving gas parcels. This process gives rise to refrigeration, with hot temperatures at the closed end and cold temperatures at the open end. Unfortunately, much of the available refrigeration is not realized because the closed end of the basic pulse tube restricts gas movement - gas at the extreme temperatures does not come in contact with the heat exchangers. The orifice pulse tube overcomes this limitation by using a valve and surge volume assembly at the warm, closed end. This allows for a residual gas velocity to remain present during the heat transfer process, thereby permitting more gas to exchange heat at the heat exchangers. This paper describes the pulse tube as a nodal regenerator and the effect residual gas velocity has on the heat transfer mechanism of the orifice pulse tube.

10. Assessment of the orifice diameter by a multigated pulsed Doppler system in children with congenital semilunar valve stenosis.

PubMed Central

de Knecht, S; Hopman, J C; Daniëls, O; Stoelinga, G B; Reneman, R S; Hoeks, A P

1989-01-01

This study investigated whether the jet diameter measured by a multigated pulsed Doppler system could be used to assess the severity of valve disease in children with pulmonary (n = 11) or aortic (n = 4) valve stenosis. The results obtained were compared with those obtained at cineangiography and at operation. Multigated pulsed Doppler examination of a stenosed valve showed a region of relatively high velocities in the velocity profile (jet flow). There was good agreement between the diameter of the disturbed region on the Doppler echocardiogram and the diameter of the jet on the lateral angiocardiogram. In severe valve stenosis the agreement between the valve diameters measured by multigated pulsed Doppler and at operation was also good. In less severe valve stenosis Doppler measurements systematically underestimated the valve diameter at operation. It is likely that the functional opening of a semilunar valve is a more relevant estimate of the degree of stenosis than the anatomical measurement of the orifice. The findings of this study indicate that multigated pulsed Doppler systems are useful in the noninvasive diagnosis of stenotic valve disease. Images Fig 1 PMID:2757874

11. A junction-orifice-fiber entrance layer model for capillary permeability: application to frog mesenteric capillaries.

PubMed

Fu, B M; Weinbaum, S; Tsay, R Y; Curry, F E

1994-11-01

The recent serial section electron microscopic studies by Adamson and Michel (1993) on microves gels of frog mesentery have revealed that the large pores in the junction strand of the interendothelial cleft are widely separated 150 nm wide orifice-like breaks whose gap height 20 nm is the same as the wide part of the cleft. In this paper a modified version of the model in Weinbaum et al. (1992) is first developed in which this orifice structure is explored in combination with a random or ordered fiber matrix layer that is at the luminal surface and/or occupies a fraction of the wide part of the cleft. This basic orifice model predicts that for the measured Lp to be achieved the fiber layer must be confined to a relatively narrow region at the entrance to the cleft where it serves as the primary molecular filter. The model provides a much better fit of the permeability P for intermediate size solutes between 1 and 2 nm radius than the previous model in Weinbaum et al., where the junction strand breaks were treated as finite depth circular or rectangular pores, but like the previous model significantly underestimates P for small ions. However, it is shown that if a small frequent pore of 1.5 nm radius with characteristic spacing comparable to the diameter of the junction proteins or a continuous narrow slit of approximately 1.5 to 2.3 nm gap height is also present in the continuous part of the junction strand, small ion permeability can also be satisfied. The 1.5 nm radius pore does not significantly change Lp, whereas the continuous narrow slit provides a contribution to Lp that is comparable to, or in the case of the 2.3 nm slit greater than, the widely spaced 150 nm orifices. Thus, for the narrow slit the contribution to Lp from the orifices can be as low as 1.0 x 10(-7) cm/s/cm H2O and it is also possible to satisfy the 2.5 fold increase in permeability that occurs when the matrix is enzymatically removed from the luminal side of the cleft, Adamson (1990). The

12. Reduction of Orifice-Induced Pressure Errors

NASA Technical Reports Server (NTRS)

Plentovich, Elizabeth B.; Gloss, Blair B.; Eves, John W.; Stack, John P.

1987-01-01

Use of porous-plug orifice reduces or eliminates errors, induced by orifice itself, in measuring static pressure on airfoil surface in wind-tunnel experiments. Piece of sintered metal press-fitted into static-pressure orifice so it matches surface contour of model. Porous material reduces orifice-induced pressure error associated with conventional orifice of same or smaller diameter. Also reduces or eliminates additional errors in pressure measurement caused by orifice imperfections. Provides more accurate measurements in regions with very thin boundary layers.

13. Flow Characteristics and Status of CFD Hydrodynamic Model Development in Sudden Contraction Manifold/Orifice Configurations

DTIC Science & Technology

2011-07-01

orifice were increased. Since the water data conforms to both the [2] criteria for cavitation and the non- cavitation discharge coefficient...characteristics, only the Diamond water data is considered further for a general correlation of hydraulic flip in cavitation . Factors that impact the non...hydraulic flip in the non- cavitation ) other than L/D are considered as mitigating at this time. Water data for D = 2.37 mm diameter orifice with

14. Feasibility and Technique for Transvaginal Natural Orifice Transluminal Endoscopic Surgery Liver Resection: A Porcine Model

PubMed Central

Katagiri, Toshio; Horgan, Santiago; Sandler, Bryan J.; Jacobsen, Garth R.; Coker, Alisa M.; Tsuchiya, Masaru; Maeda, Tetsuya; Kaneko, Hironori

2017-01-01

Introduction: Natural orifice transluminal endoscopic surgery (NOTES) is a challenging minimally invasive procedure. Although laparoscopic techniques for liver resection are gaining acceptance worldwide, few studies have investigated NOTES liver resection. We used a porcine model to assess the feasibility and safety of transvaginal NOTES liver resection (TV NOTES LR). Materials and Methods: Nine female pigs underwent TV NOTES LR. A nonsurvival acute porcine model with general anesthesia was used in all cases. Using hybrid NOTES technique, we placed only 1 umbilical 12-mm umbilical trocar in the abdominal wall, which was used to create pneumoperitoneum. A laparoscope was then advanced to obtain intra-abdominal visualization. A 15-mm vaginal trocar was inserted under direct laparoscopic vision, and a flexible endoscope was introduced through the vaginal trocar. A long, flexible grasper and endocavity retractor were used to stably retract the liver. The liver edge was partially transected using energy devices inserted through the umbilical trocar. To transect the left lateral lobe, a flexible linear stapler was inserted alongside the vaginal trocar. A specimen extraction bag was deployed and extracted transvaginally. Blood loss, bile leakage, operative time, and specimen size were evaluated. Necropsy studies were performed after the procedures. Results: Eighteen transvaginal NOTES partial liver resections and 4 transvaginal NOTES left lateral lobectomies were successfully performed on 9 pigs. Mean operative time was 165.8 minutes, and mean estimated blood loss was 76.6 mL. All TV NOTES LRs were performed without complications or deaths. Necropsy showed no bile leakage from remnant liver. Conclusions: Our porcine model suggests that TV NOTES LR is technically feasible and safe and has the potential for clinical use as a minimally invasive alternative to conventional laparoscopic liver resection. PMID:28030435

15. A cone-beam computed tomographic study of root canal systems in mandibular premolars in a Turkish population: Theoretical model for determining orifice shape

PubMed Central

Arslan, Hakan; Capar, Ismail Davut; Ertas, Elif Tarim; Ertas, Huseyin; Akcay, Merve

2015-01-01

Objective: The purposes of this retrospective study were to represent a newly designed theoretical model for determining orifice shape and morphologic properties of mandibular premolars and to correlate these findings with each other. Materials and Methods: A total of 287 mandibular premolar images obtained from 88 patients by cone-beam computed tomography were included in this study. The measurements were performed below the cementoenamel junction, and different orifice configurations were defined in accordance with various ratios. The age and gender of the patient, the tooth type and position, the number of roots, orifice configuration, root canal configuration, presence of C-shaped canal, and the presence of radicular groove were recorded. It was also recorded whether the root canal becomes round or not and if any, length of the root canal from the orifice to the section in which it becomes round. Furthermore, the theoretical model for determining orifice shape was defined after measurements. The orifice shape was determined as round, oval, flat, keyhole-shaped, and T-shaped, and orifices with short, normal length, and long isthmus. Statistical analyses were performed using Chi-square and Spearman's rank correlation tests (P = 0.05). Results: Orifice configurations were, usually, flat (37%), or keyhole-shaped (23%). The prevalence of T-shaped was found to be 3.8%. The prevalence of C-shaped canals was found to be 2.1%. The percentage of root canals that became round in the middle or apical thirds was 95.1%. Radicular grooves were detected in 37 (24%) of first premolars and six (4.5%) of second premolars. Statistical analysis revealed that the mean length of distance until the canal reached a round shape varied according to age group (r = −0.270; P < 0.001). There was a statistically significant difference between radicular groove and tooth type (P < 0.001). Conclusions: The mean length of distance until the canal reached a round shape correlated with the

16. Pulsed Plasma Accelerator Modeling

NASA Technical Reports Server (NTRS)

Goodman, M.; Kazeminezhad, F.; Owens, T.

2009-01-01

This report presents the main results of the modeling task of the PPA project. The objective of this task is to make major progress towards developing a new computational tool with new capabilities for simulating cylindrically symmetric 2.5 dimensional (2.5 D) PPA's. This tool may be used for designing, optimizing, and understanding the operation of PPA s and other pulsed power devices. The foundation for this task is the 2-D, cylindrically symmetric, magnetohydrodynamic (MHD) code PCAPPS (Princeton Code for Advanced Plasma Propulsion Simulation). PCAPPS was originally developed by Sankaran (2001, 2005) to model Lithium Lorentz Force Accelerators (LLFA's), which are electrode based devices, and are typically operated in continuous magnetic field to the model, and implementing a first principles, self-consistent algorithm to couple the plasma and power circuit that drives the plasma dynamics.

17. Variable orifice flow regulator

NASA Technical Reports Server (NTRS)

Christianson, Rollin C. (Inventor)

1991-01-01

A flow regulator for high-pressure fluids at elevated temperatures includes a body having a flow passage extending between inlet and outlet openings. First and second orifice members are arranged in the flow passage so at least one of the orifice members can be moved transversely in relation to the flow passage between one operating position where the two orifice openings are aligned for establishing a maximum flow rate of fluids flowing through the flow passage and at least one other operating position in which the two openings are moderately misaligned with one another for establishing a predetermined reduced flow rate of fluids flowing through the flow passage.

18. Modeling of pulsed propellant reorientation

NASA Technical Reports Server (NTRS)

Patag, A. E.; Hochstein, J. I.; Chato, D. J.

1989-01-01

Optimization of the propellant reorientation process can provide increased payload capability and extend the service life of spacecraft. The use of pulsed propellant reorientation to optimize the reorientation process is proposed. The ECLIPSE code was validated for modeling the reorientation process and is used to study pulsed reorientation in small-scale and full-scale propellant tanks. A dimensional analysis of the process is performed and the resulting dimensionless groups are used to present and correlate the computational predictions for reorientation performance.

19. Drilling Precise Orifices and Slots

NASA Technical Reports Server (NTRS)

Richards, C. W.; Seidler, J. E.

1983-01-01

Reaction control thrustor injector requires precisely machined orifices and slots. Tooling setup consists of rotary table, numerical control system and torque sensitive drill press. Components used to drill oxidizer orifices. Electric discharge machine drills fuel-feed orifices. Device automates production of identical parts so several are completed in less time than previously.

20. Direct Numerical Simulations of Sound-Orifice-Boundary Layer Interaction

Zhang, Qi; Bodony, Daniel

2015-11-01

We report on a series of direct numerical simulations (DNS) of the interaction of a monochromatic incident acoustic field with a cavity-backed circular orifice in the presence of laminar and turbulent boundary layers of freestream Mach number 0.5 and momentum thickness Reynolds number 2,300, with application to acoustic liners. The simulations show that the addition of the orifice increases the drag and can induce laminar-to-turbulent transition at sufficiently high acoustic levels. Furthermore, the sound-orifice-boundary layer system support three distinct timescales whose spatial distributions change with the phase of the incident sound. Details of the near-orifice interaction are studied to create a model of the orifice discharge coefficient that is part of a time-domain, nonlinear reduced-order model (ROM) for the liner impedance. Comparisons between the ROM-predicted and DNS-measured near-orifice flow and acoustic impedance are given.

1. Numerical analysis of eccentric orifice plate using ANSYS Fluent software

Zahariea, D.

2016-11-01

In this paper the eccentric orifice plate is qualitative analysed as compared with the classical concentric orifice plate from the point of view of sedimentation tendency of solid particles in the fluid whose flow rate is measured. For this purpose, the numerical streamlines pattern will be compared for both orifice plates. The numerical analysis has been performed using ANSYS Fluent software. The methodology of CFD analysis is presented: creating the 3D solid model, fluid domain extraction, meshing, boundary condition, turbulence model, solving algorithm, convergence criterion, results and validation. Analysing the numerical streamlines, for the concentric orifice plate can be clearly observed two circumferential regions of separated flows, upstream and downstream of the orifice plate. The bottom part of these regions are the place where the solid particles could sediment. On the other hand, for the eccentric orifice plate, the streamlines pattern suggest that no sedimentation will occur because at the bottom area of the pipe there are no separated flows.

2. Pulse Detonation Engine Modeled

NASA Technical Reports Server (NTRS)

Paxson, Daniel E.

2001-01-01

Pulse Detonation Engine Technology is currently being investigated at Glenn for both airbreathing and rocket propulsion applications. The potential for both mechanical simplicity and high efficiency due to the inherent near-constant-volume combustion process, may make Pulse Detonation Engines (PDE's) well suited for a number of mission profiles. Assessment of PDE cycles requires a simulation capability that is both fast and accurate. It should capture the essential physics of the system, yet run at speeds that allow parametric analysis. A quasi-one-dimensional, computational-fluid-dynamics-based simulation has been developed that may meet these requirements. The Euler equations of mass, momentum, and energy have been used along with a single reactive species transport equation, and submodels to account for dominant loss mechanisms (e.g., viscous losses, heat transfer, and valving) to successfully simulate PDE cycles. A high-resolution numerical integration scheme was chosen to capture the discontinuities associated with detonation, and robust boundary condition procedures were incorporated to accommodate flow reversals that may arise during a given cycle. The accompanying graphs compare experimentally measured and computed performance over a range of operating conditions for a particular PDE. Experimental data were supplied by Fred Schauer and Jeff Stutrud from the Air Force Research Laboratory at Wright-Patterson AFB and by Royce Bradley from Innovative Scientific Solutions, Inc. The left graph shows thrust and specific impulse, Isp, as functions of equivalence ratio for a PDE cycle in which the tube is completely filled with a detonable hydrogen/air mixture. The right graph shows thrust and specific impulse as functions of the fraction of the tube that is filled with a stoichiometric mixture of hydrogen and air. For both figures, the operating frequency was 16 Hz. The agreement between measured and computed values is quite good, both in terms of trend and

3. Oscillatory flow around discs and through orifices

Debernardinis, B.; Graham, J. M. R.; Parker, K. H.

1980-11-01

Examples of unsteady, axisymmetric, separated flows are modeled, including unbounded oscillatory flow around a disk and bounded oscillatory flow through a sharp-edged orifice. Calculations are made, assuming that the flow is inviscid and that the shed vortex sheets can be represented by sequences of discrete vortex rings. The solid bodies, i.e., the disk or the orifice and bounding tube, are also represented by a distribution of bound discrete vortex rings whose strenghts are chosen to satisfy the Neumann or zero normal velocity boundary condition. The results of flow visualization experiments and, for the orifice, pressure drop measurements are reported. In general, the gross properties of the flows are predicted accurately.

4. Effect of grazing flow on steady-state resistance of isolated square-edged orifices

NASA Technical Reports Server (NTRS)

Rogers, T.

1976-01-01

Steady state diagnostic testing of an isolated orifice has shown the nature of the interaction between grazing and orifice flow causing the large increase in orifice resistance for both inflow and outflow. A simple inviscid interaction model is developed which uses thin aerofoil theory to account for pressure forces exerted at the interface between the orifice and grazing flow together with a one-dimensional discharge coefficient concept. The effect of grazing flow boundary layer thickness is also included in the model. Resistance measurements for each orifice tested, over a wide range of grazing flow speeds and flow rates, collapse into a single curve when plotted in terms of effective discharge coefficient against orifice to grazing velocity ratio. The correlation curves for inflow and outflow are different. Data for clustered orifices collapse in the same way as those for the single orifice. The effect of boundary layer thickness is compared with model predictions.

5. High Pressure Water Stripping Using Multi-Orifice Nozzles

NASA Technical Reports Server (NTRS)

Hoppe, David

1999-01-01

The use of multi-orifice rotary nozzles greatly increases the speed and stripping effectiveness of high pressure water blasting systems, but also greatly increases the complexity of selecting and optimizing the operating parameters. The rotational speed of the nozzle must be coupled with its transverse velocity as it passes across the surface of the substrate being stripped. The radial and angular positions of each orifice must be included in the analysis of the nozzle configuration. Orifices at the outer edge of the nozzle head move at a faster rate than the orifices located near the center. The energy transmitted to the surface from the impact force of the water stream from an outer orifice is therefore spread over a larger area than energy from an inner orifice. Utilizing a larger diameter orifice in the outer radial positions increases the total energy transmitted from the outer orifice to compensate for the wider distribution of energy. The total flow rate from the combination of all orifices must be monitored and should be kept below the pump capacity while choosing orifice to insert in each position. The energy distribution from the orifice pattern is further complicated since the rotary path of all the orifices in the nozzle head pass through the center section. All orifices contribute to the stripping in the center of the path while only the outer most orifice contributes to the stripping at the edge of the nozzle. Additional orifices contribute to the stripping from the outer edge toward the center section. With all these parameters to configure and each parameter change affecting the others, a computer model was developed to track and coordinate these parameters. The computer simulation graphically indicates the cumulative affect from each parameter selected. The result from the proper choices in parameters is a well designed, highly efficient stripping system. A poorly chosen set of parameters will cause the nozzle to strip aggressively in some areas

6. Active Control of Liner Impedance by Varying Perforate Orifice Geometry

NASA Technical Reports Server (NTRS)

Ahuji, K. K.; Gaeta, R. J., Jr.

2000-01-01

The present work explored the feasibility of controlling the acoustic impedance of a resonant type acoustic liner. This was accomplished by translating one perforate over another of the same porosity creating a totally new perforate that had an intermediate porosity. This type of adjustable perforate created a variable orifice perforate whose orifices were non-circular. The key objective of the present study was to quantify, the degree of attenuation control that can be achieved by applying such a concept to the buried septum in a two-degree-of-freedom (2DOF) acoustic liner. An additional objective was to examine the adequacy of the existing impedance models to explain the behavior of the unique orifice shapes that result from the proposed silding perforate concept. Different orifice shapes with equivalent area were also examined to determine if highly non-circular orifices had a significant impact on the impedance.

7. Pulse height model for deuterated scintillation detectors

Wang, Haitang; Enqvist, Andreas

2015-12-01

An analytical model of light pulse height distribution for finite deuterated scintillation detectors is created using the impulse approximation. Particularly, the energy distribution of a scattered neutron is calculated based on an existing collision probability scheme for general cylindrical shaped detectors considering double differential cross-sections. The light pulse height distribution is analytically and numerically calculated by convoluting collision sequences with the light output function for an EJ-315 detector from our measurements completed at Ohio University. The model provides a good description of collision histories capturing transferred neutron energy in deuterium-based scintillation materials. The resulting light pulse height distribution details pulse compositions and their corresponding contributions. It shows that probabilities of neutron collision with carbon and deuterium nuclei are comparable, however the light pulse amplitude due to collisions with carbon nuclei is small and mainly located at the lower region of the light pulse distribution axis. The model can explore those neutron interaction events that generate pulses near or below a threshold that would be imposed in measurements. A comparison is made between the light pulse height distributions given by the analytical model and measurements. It reveals a significant probability of a neutron generating a small light pulse due to collisions with carbon nuclei when compared to larger light pulse generated by collisions involving deuterium nuclei. This model is beneficial to understand responses of scintillation materials and pulse compositions, as well as nuclei information extraction from recorded pulses.

8. Balanced Orifice Plate

NASA Technical Reports Server (NTRS)

Kelley, Anthony R. (Inventor); Buskirk, Paul D. (Inventor)

2006-01-01

An orifice plate for use in a conduit through which fluid flows is defined by a central circular region having a radius R, and a ring-shaped region surrounding the central circular region. The ring-shaped region has holes formed therethrough with those holes centered at each radius R thereof satisfying a relationship A(sub R)=al(X(sub R)V(sub R)(sup b)) where A(sub R) is a sum of areas of those holes having centers at radius R, X(sub R) is a flow coefficient at radius R, V(sub R) is a velocity of the fluid that is to flow through the conduit at radius R, b is a constant selected to make at least one process variable (associated with the fluid that is to flow through the conduit) approximately equal at each radius R, and a is a constant that is equal to (X(sub R)A(sub R)V(sub R)(sup b)) at each radius R.

9. High Pressure Water Stripping Using Multi-Orifice Nozzles

NASA Technical Reports Server (NTRS)

Hoppe, David T.

1998-01-01

The use of multi-orifice rotary nozzles not only increases the speed and stripping effectiveness of high pressure water blasting systems, but also greatly increases the complexity of selecting and optimizing the operating parameters. The rotational speed of the nozzle must be coupled with the transverse velocity of the nozzle as it passes across the surface of the substrate being stripped. The radial and angular positions of each orifice must be included in the analysis of the nozzle configuration. Since orifices at the outer edge of the nozzle head move at a faster rate than the orifice located near the center, the energy impact force of the water stream from the outer orifice is spread over a larger area than the water streams from the inner orifice. Utilizing a larger diameter orifice in the outer radial positions increases the energy impact to compensate for its wider force distribution. The total flow rate from the combination of orifices must be monitored and kept below the pump capacity while choosing an orifice to insert in each position. The energy distribution from the orifice pattern is further complicated since the rotary path of all orifices in the nozzle head pass through the center section, contributing to the stripping in this area while only the outer most orifice contributes to the stripping in the shell area at the extreme outside edge of the nozzle. From t he outer most shell to the center section, more orifices contribute to the stripping in each progressively reduced diameter shell. With all these parameters to configure and each parameter change affecting the others, a computer model was developed to track and coordinate these parameters. The computer simulation responds by graphically indicating the cumulative affect from each parameter selected. The results from the proper choices in parameters is a well designed, highly efficient stripping system. A poorly chosen set of parameters will cause the nozzle to strip aggressively in some areas

10. Program sizes flange-tap orifice plate

SciTech Connect

Hogsett, J.E.

1981-03-23

A program developed for the TI-59 programmable calculator computes the differential pressure across an orifice, the gas flow through an orifice, or the orifice-plate bore for orifice plates with flange taps. Based on equations and data from L.K. Spinks, the program saves time in extracting from charts, tables, and graphs the values required to perform the calculations.

11. Numerical simulation of particle dynamics in an orifice-electrode system. Application to counting and sizing by impedance measurement.

PubMed

Isèbe, Damien; Nérin, Philippe

2013-04-01

This paper describes how to numerically tackle the problem of counting and sizing particles by impedance measurement in an orifice-electrode system. The model allows to simulate the particle dynamics submitted to strong hydrodynamic stresses through a microorifice and to compute the voltage pulses generated by the modification of the inner dielectric medium. This approach gives important information about particles size distribution and allows to quantify the role of trajectory and orientation of particles on the size measurement.

12. The effect of grazing flow on the steady state resistance of square-edged orifices

NASA Technical Reports Server (NTRS)

Rogers, T.; Hersh, A. S.

1975-01-01

A simple inviscid interaction model has been developed which uses thin airfoil theory to account for pressure forces exerted at the interface between the orifice and grazing flow together with a one-dimensional discharge coefficient concept. The effect of grazing flow boundary layer thickness was also included in the model. Resistance measurements for a wide range of grazing flow speeds and orifice flow rates collapse into a single curve when plotted in terms of effective discharge coefficient versus orifice-to-grazing velocity ratio. The correlation curves for inflow and outflow are different. Data for clustered orifices collapse in the same way as the single orifice. The effect of boundary layer thickness is compared with model predictions. The effect of orifice length-diameter ratio is shown to be significant for inflow but negligible for outflow.

13. Modeling of ultrafast laser pulse propagation

Kolesik, Miroslav; Brown, Jeffrey; Bahl, Anand

2016-05-01

Computer simulations of ultrafast optical pulses face multiple challenges. This requires one to construct a propagation model to reduce the Maxwell system so that it can be efficiently simulated at the temporal and spatial scales relevant to experiments. The second problem concerns the light-matter interactions, demanding novel approaches for gaseous and condensed media alike. As the nonlinear optics pushes into new regimes, the need to honor the first principles is ever greater, and requires striking a balance between computational complexity and physical fidelity of the model. With the emphasis on the dynamics in intense optical pulses, this paper discusses some recent developments and promising directions in the field of ultrashort pulse modeling.

14. Influence of Geometry and Flow Variation on Jet Mixing and NO Formation in a Model Staged Combustor Mixer with Eight Orifices

NASA Technical Reports Server (NTRS)

Samuelsen, G. S.; Sowa, W. A.; Hatch, M. S.

1996-01-01

A series of non-reacting parametric experiments was conducted to investigate the effect of geometric and flow variations on mixing of cold jets in an axis-symmetric, heated cross flow. The confined, cylindrical geometries tested represent the quick mix region of a Rich-Burn/Quick-Mix/Lean-Burn (RQL) combustor. The experiments show that orifice geometry and jet to mainstream momentum-flux ratio significantly impact the mixing characteristic of jets in a cylindrical cross stream. A computational code was used to extrapolate the results of the non-reacting experiments to reacting conditions in order to examine the nitric oxide (NO) formation potential of the configurations examined. The results show that the rate of NO formation is highest immediately downstream of the injection plane. For a given momentum-flux ratio, the orifice geometry that mixes effectively in both the immediate vicinity of the injection plane, and in the wall regions at downstream locations, has the potential to produce the lowest NO emissions. The results suggest that further study may not necessarily lead to a universal guideline for designing a low NO mixer. Instead, an assessment of each application may be required to determine the optimum combination of momentum-flux ratio and orifice geometry to minimize NO formation. Experiments at reacting conditions are needed to verify the present results.

15. The role of a computed tomography-based image registered navigation system for natural orifice transluminal endoscopic surgery: a comparative study in a porcine model

PubMed Central

Fernández-Esparrach, G.; San José Estépar, R.; Guarner-Argente, C.; Martínez-Pallí, G.; Navarro, R.; Rodríguez de Miguel, C.; Córdova, H.; Thompson, C. C.; Lacy, A. M.; Donoso, L.; Ayuso-Colella, J. R.; Ginès, A.; Pellisé, M.; Llach, J.; Vosburgh, K. G.

2011-01-01

Background and study aims Most natural orifice transluminal endoscopic surgery (NOTES) procedures have been performed in animal models through the anterior stomach wall, but this approach does not provide efficient access to all anatomic areas of interest. Moreover, injury of the adjacent structures has been reported when using a blind access. The aim of the current study was to assess the utility of a CT-based (CT: computed tomography) image registered navigation system in identifying safe gastrointestinal access sites for NOTES and identifying intraperitoneal structures. Methods A total of 30 access procedures were performed in 30 pigs: anterior gastric wall (n = 10), posterior gastric wall (n = 10), and anterior rectal wall (n = 10). Of these, 15 procedures used image registered guidance (IR-NOTES) and 15 procedures used a blind access (NOTES only). Timed abdominal exploration was performed with identification of 11 organs. The location of the endoscopic tip was tracked using an electromagnetic tracking system and was recorded for each case. Necropsy was performed immediately after the procedure. The primary outcome was the rate of complications; secondary outcome variables were number of organs identified and kinematic measurements. Results A total of 30 animals weighting a mean (± SD) of 30.2 ± 6.8 kg were included in the study. The incision point was correctly placed in 11 out of 15 animals in each group (73.3 %). The mean peritoneoscopy time and the number of properly identified organs were equivalent in the two groups. There were eight minor complications (26.7 %), two (13.3 %) in the IR-NOTES group and six (40.0 %) in the NOTES only group (P = n. s.). Characteristics of the endoscope tip path showed a statistically significant improvement in trajectory smoothness of motion for all organs in the IR-NOTES group. Conclusion The image registered system appears to be feasible in NOTES procedures and results from this study suggest that image registered

16. Generic Sensor Modeling Using Pulse Method

NASA Technical Reports Server (NTRS)

Helder, Dennis L.; Choi, Taeyoung

2005-01-01

Recent development of high spatial resolution satellites such as IKONOS, Quickbird and Orbview enable observation of the Earth's surface with sub-meter resolution. Compared to the 30 meter resolution of Landsat 5 TM, the amount of information in the output image was dramatically increased. In this era of high spatial resolution, the estimation of spatial quality of images is gaining attention. Historically, the Modulation Transfer Function (MTF) concept has been used to estimate an imaging system's spatial quality. Sometimes classified by target shapes, various methods were developed in laboratory environment utilizing sinusoidal inputs, periodic bar patterns and narrow slits. On-orbit sensor MTF estimation was performed on 30-meter GSD Landsat4 Thematic Mapper (TM) data from the bridge pulse target as a pulse input . Because of a high resolution sensor s small Ground Sampling Distance (GSD), reasonably sized man-made edge, pulse, and impulse targets can be deployed on a uniform grassy area with accurate control of ground targets using tarps and convex mirrors. All the previous work cited calculated MTF without testing the MTF estimator's performance. In previous report, a numerical generic sensor model had been developed to simulate and improve the performance of on-orbit MTF estimating techniques. Results from the previous sensor modeling report that have been incorporated into standard MTF estimation work include Fermi edge detection and the newly developed 4th order modified Savitzky-Golay (MSG) interpolation technique. Noise sensitivity had been studied by performing simulations on known noise sources and a sensor model. Extensive investigation was done to characterize multi-resolution ground noise. Finally, angle simulation was tested by using synthetic pulse targets with angles from 2 to 15 degrees, several brightness levels, and different noise levels from both ground targets and imaging system. As a continuing research activity using the developed sensor

17. Modelling the pulse transformer in SPICE

Godlewska, Malgorzata; Górecki, Krzysztof; Górski, Krzysztof

2016-01-01

The paper is devoted to modelling pulse transformers in SPICE. It shows the character of the selected models of this element, points out their advantages and disadvantages, and presents the results of experimental verification of the considered models. These models are characterized by varying degrees of complexity - from linearly coupled linear coils to nonlinear electrothermal models. The study was conducted for transformer with ring cores made of a variety of ferromagnetic materials, while exciting the sinusoidal signal of a frequency 100 kHz and different values of load resistance. The transformers operating conditions under which the considered models ensure the acceptable accuracy of calculations are indicated.

18. Modeling Pulsed Laser Melting of Embedded Nanoparticles

Sawyer, Carolyn Anne

A model of pulsed laser melting of embedded nanoparticles is introduced. Pulsed laser melting (PLM) is commonly used to achieve a fast quench rate in nanoparticles; this model enables a better understanding of the influence of PLM on the size distribution of nanoparticles, which is crucial for studying or using their size-dependent properties. The model includes laser absorption according to the Mie theory, a full heat transport model, and rate equations for nucleation, growth, coarsening, and melting and freezing of nanoparticles embedded in a transparent matrix. The effects of varying the laser parameters and sample properties are studied, as well as combining PLM and rapid thermal annealing (RTA) processing steps on the same sample. A general theory for achieving narrow size distributions of nanoparticles is presented, and widths as narrow as 12% are achieved using PLM and RTA.

19. Unlimited-Length Proctocolectomy Utilizing Sequential Intussusception and Pull-Through: Novel Clean Endolumenal NOTE-Assisted Technique With Transanal Natural Orifice Specimen Extraction Without Rectal Stump Opening in a Porcine Model.

PubMed

Kvasha, Anton; Khalifa, Muhammad; Biswas, Seema; Hamoud, Mohamad; Nordkin, Dmitri; Bramnik, Zakhar; Willenz, Udi; Farraj, Moaad; Waksman, Igor

2016-10-01

Transanal, hybrid natural orifice translumenal endoscopic surgery (NOTES) and NOTES-assisted natural orifice specimen extraction techniques hold promise as leaders in the field of natural orifice surgery. We report the feasibility of a novel NOTES assisted technique for unlimited length, clean, endolumenal proctocolectomy in a porcine model. This technique is a modification of a transanal intussusception and pull-through procedure recently published by our group. Rectal mobilization was achieved laparoscopically; this was followed by a transanal recto-rectal intussusception and pull-through (IPT). IPT was established in a stepwise fashion. First, the proximal margin of resection was attached laparoscopically to the shaft of the anvil of an end-to-end circular stapler with a ligature around the rectum. Second, this complex was pulled transanally to produce IPT. To achieve an unlimited-length proctocolectomy, the IPT step was repeated several times prior to bowel resection. This was facilitated by removing the ligature applied in the first step of this procedure. Once sequential IPT established the desired length of bowel to be resected, a second ligature was placed around the rectum approximating the proximal and distal resection margins. The specimen was resected and extracted by making a full-thickness incision through the 2 bowel walls. The anastomosis was achieved by deploying the stapler. The technique was found to be feasible. Peritoneal samples, collected after transanal specimen extraction, did not demonstrate bacterial growth. The minimally invasive nature of this evolving technique as well as its aseptic bowel manipulation has the potential to limit the complications associated with abdominal wall incision and surgical site infection.

20. Effect of mitral orifice shape on intra-ventricular filling fluid dynamics

Okafor, Ikechukwu; Angirish, Yagna; Yoganathan, Ajit; Santhanakrishnan, Arvind

2013-11-01

The natural geometry of the mitral orifice is D-shaped. However, most current designs of prosthetic valves employ O-shaped orifice geometry. The goal of this study was to compare the effect of geometrical modification between the D and O orifice on the intra-ventricular fluid dynamics during diastolic filling. The different mitral orifice geometries were incorporated into an in vitro left heart simulator consisting of a flexible-walled anatomical left ventricle (LV) physical model enclosed in an acrylic housing. Physiological flow rates and pressures were obtained via tuning systemic resistance and compliance elements in the flow loop. A programmable piston pump was used to generate the LV model wall motion. 2D Particle image velocimetry measurements were conducted along multiple longitudinal planes perpendicular to the annulus plane. During peak diastole, the incoming jet width at the LV central plane was smaller for the D-orifice than that of the O-orifice. Further, the core of the vortex ring in the D-orifice was reduced in size compared to that of the O-orifice. The spatiotemporal spreading of the inflow jet as well as the propagation of the vortex ring will be discussed. This study was funded by a grant from the National Heart, Lung and Blood Institute (RO1HL70262).

1. Anatomical Variation of Human Collector Channel Orifices

PubMed Central

Bentley, Michael D.; Hann, Cheryl R.; Fautsch, Michael P.

2016-01-01

Purpose To examine the anatomical variation of normal human collector channel orifices and their relationship with Schlemm's canal. Methods Ten human anterior segments fixed by immersion or perfusion were dissected radially and further divided by fine dissection into corresponding inner and outer wall segments. The tissues were dehydrated, critical-point dried, sputter coated, and examined by scanning electron microscopy. Images were obtained at magnifications from ×200 to ×10,000. Selected radial collector channel regions were processed for plastic embedding. Results Two classes of collector channel orifices were identified. Simple oval orifices (54.7 ± 4.6–μm diameter) were lined with endothelial cells and most often occurred on a planar region of Schlemm's canal outer wall. Complex orifices (62.7 ± 3.4–μm diameter) were often found associated with septal columns and bridges, and typically covered with flap-like structures (10–40 μm) that extended between the inner and outer wall and over the collector channel orifices. Both simple and complex orifices had complete or partial lip-like rims. In orifices with partial rims, a trough-like groove was often visible on the outer wall surface opposite the lip. Transected septa and inner and outer wall adhesion sites were often found in association with complex collector channel orifices. Conclusions Collector channel orifice structure varied from simple ovals to complex tethered flaps and bridges. Collector channel orifices with complex flaps connect the inner and outer walls of Schlemm's canal, and may serve to enhance and regulate aqueous outflow in these regions. PMID:26975026

2. Gas Generator Feedline Orifice Sizing Methodology: Effects of Unsteadiness and Non-Axisymmetric Flow

NASA Technical Reports Server (NTRS)

Rothermel, Jeffry; West, Jeffrey S.

2011-01-01

Engine LH2 and LO2 gas generator feed assemblies were modeled with computational fluid dynamics (CFD) methods at 100% rated power level, using on-center square- and round-edge orifices. The purpose of the orifices is to regulate the flow of fuel and oxidizer to the gas generator, enabling optimal power supply to the turbine and pump assemblies. The unsteady Reynolds-Averaged Navier-Stokes equations were solved on unstructured grids at second-order spatial and temporal accuracy. The LO2 model was validated against published experimental data and semi-empirical relationships for thin-plate orifices over a range of Reynolds numbers. Predictions for the LO2 square- and round-edge orifices precisely match experiment and semi-empirical formulas, despite complex feedline geometry whereby a portion of the flow from the engine main feedlines travels at a right-angle through a smaller-diameter pipe containing the orifice. Predictions for LH2 square- and round-edge orifice designs match experiment and semi-empirical formulas to varying degrees depending on the semi-empirical formula being evaluated. LO2 mass flow rate through the square-edge orifice is predicted to be 25 percent less than the flow rate budgeted in the original engine balance, which was subsequently modified. LH2 mass flow rate through the square-edge orifice is predicted to be 5 percent greater than the flow rate budgeted in the engine balance. Since CFD predictions for LO2 and LH2 square-edge orifice pressure loss coefficients, K, both agree with published data, the equation for K has been used to define a procedure for orifice sizing.

3. [Natural orifice transluminal endoscopic surgery: current situation].

PubMed

2008-10-01

Natural orifice transluminal endoscopic surgery (NOTES) is the paradigm of the evolution of minimally invasive surgery. The laparoscopic has introduced new ideas in general surgery, one of them being that modern surgery is the work of multidisciplinary teams. A clear example of this is provided by NOTES. The aim of this type of surgery is to perform conventional laparoscopic procedures without incision, using flexible endoscopic technology usually employed in the diagnosis and treatment of intraluminal lesions and reaching the inside of the abdominal cavity through natural orifices (mouth, anus, vagina and even urethra). This type of access opens a highly interesting field for certain types of patients, such as those with high surgical risk, the morbidly obese, and those with multiple prior abdominal interventions or surgical wound infections. Animal models have shown that a wide variety of interventions (cholecystectomy, appendicectomy, splenectomy, hysterectomy, tubal ligations, gastroenteroanastomosis, peritoneoscopy, liver biopsy and herniorrhaphy, among others) can be performed. However, before use in humans, this new technique must be shown to be safe and to provide real advantages for patients. To do this, a series of issues, including safe methods for closure of the gastric incision and the avoidance of infections, among others, must be solved. Another critical element for the development of this new type of surgery is the creation of appropriate instrumentation, requiring input not only from medical professionals but also from engineers and industry. The present article describes the major advances made in NOTES since this technique was first described and analyzes the risks and potential benefits associated with this novel procedure.

4. Aerodynamic estimates of induced anterior orifice openings in human subjects.

PubMed

Guyette, T W; Smith, B E; Reisberg, D J

1994-05-01

This study first examined the accuracy of pressure-flow area estimates of experimental openings in anterior palatal obturators of three adult subjects. Second, we evaluated pressure-flow measures of the same experimental openings using a model. Results indicated that percent error in orifice estimates was slightly higher for induced openings in human subjects (13%) versus those in the model (11%). Results for our human subjects were similar to those reported by previous investigators.

5. Program computes orifice-meter flow rate

SciTech Connect

Martin, J.R.

1981-10-12

Useful for designing new metering stations or figuring flow rates through existing ones, the program developed for the Tl-59 programmable calculator computes the gas flow rate through an orifice-meter run. The user inputs are the orifice diameter, meter run ID, flowing gas temperature, density, flowing gas pressure, and differential pressure. The program's results are more accurate than those of flow charts or slide-rule-type calculators.

6. Improved Orifice Plate for Spray Gun

NASA Technical Reports Server (NTRS)

Cunningham, W.

1986-01-01

Erratic spray pattern of commercial spray gun changed to repeatable one by simple redesign of two parts. In modified spray gun orifice plate and polytetrafluoroethylene bushing redesigned to assure centering and alignment with nozzle. Such improvement useful in many industrial applications requiring repeatable spray patterns. Might include spraying of foam insulation, paint, other protective coatings, detergents, abrasives, adhesives, process chemicals, or fuels. Unmodified spray gun produces erratic spray because lateral misalignment between orifice plate and nozzle.

7. Modeling of ablation threshold dependence on pulse duration for dielectrics with ultrashort pulsed laser

Sun, Mingying; Zhu, Jianqiang; Lin, Zunqi

2017-01-01

We present a numerical model of plasma formation in ultrafast laser ablation on the dielectrics surface. Ablation threshold dependence on pulse duration is predicted with the model and the numerical results for water agrees well with the experimental data for pulse duration from 140 fs to 10 ps. Influences of parameters and approximations of photo- and avalanche-ionization on the ablation threshold prediction are analyzed in detail for various pulse lengths. The calculated ablation threshold is strongly dependent on electron collision time for all the pulse durations. The complete photoionization model is preferred for pulses shorter than 1 ps rather than the multiphoton ionization approximations. The transition time of inverse bremsstrahlung absorption needs to be considered when pulses are shorter than 5 ps and it can also ensure the avalanche ionization (AI) coefficient consistent with that in multiple rate equations (MREs) for pulses shorter than 300 fs. The threshold electron density for AI is only crucial for longer pulses. It is reasonable to ignore the recombination loss for pulses shorter than 100 fs. In addition to thermal transport and hydrodynamics, neglecting the threshold density for AI and recombination could also contribute to the disagreements between the numerical and the experimental results for longer pulses.

8. TWO-PHASE FLOW OF TWO HFC REFRIGERANT MIXTURES THROUGH SHORT-TUBE ORIFICES

EPA Science Inventory

The report gives results of an experimental investigation to develop an acceptable flow model for short tube orifice expansion devices used in heat pumps. The refrigerants investigated were two hydrofluorocarbon (HFC) mixtures considered hydrochlorofluorocarbon (HCFC)-22 replacem...

9. Subsonic tests of an all-flush-pressure-orifice air data system

NASA Technical Reports Server (NTRS)

Larson, T. J.; Siemers, P. M., III

1981-01-01

The use of an all-flush-pressure-orifice array as a subsonic air data system was evaluated in flight and wind tunnel tests. Two orifice configurations were investigated. Both used orifices arranged in a cruciform pattern on the airplane nose. One configuration also used orifices on the sides of the fuselage for a source of static pressure. The all-nose-orifice configuration was similar to the shuttle entry air data system (SEADS). The flight data were obtained with a KC-135A airplane. The wind tunnel data were acquired with a 0.035-scale model of the KC-135A airplane. With proper calibration, several orifices on the vertical centerline of the vehicle's nose were found to be satisfactory for the determination of total pressure and angle of attack. Angle of sideslip could be accurately determined from pressure measurements made on the horizontal centerline of the aircraft. Orifice pairs were also found that provided pressure ratio relationships suitable for the determination of Mach number. The accuracy that can be expected for the air data determined with SEADS during subsonic orbiter flight is indicated.

10. A power law approach to orifice flow rate calibration.

PubMed

Rhinehart, R Russell; Gebreyohannes, Solomon; Sridhar, Upasana Manimegalai; Patrachari, Anirudh; Rahaman, M S

2011-04-01

Although standards for orifice flow meter design, installation, and calibration are supported herein, noncompliant devices exist in many pilot-, lab-scale, and on-board applications. For these, a common calibration practice is to preserve the ideal square root relation and determine a device specific discharge coefficient value. This work provides theoretical and empirical analyses to support relaxing the square root relation between orifice pressure drop and flow rate for noncompliant devices. The resulting power law relation is shown to improve accuracy, precision, and rangeability. Whether a device specific square root or power law model is used, it requires off-line or in-line calibration data. As such, a power law calibration model may only be useful for on-board and small-scale applications.

11. Effects of Gravity on Bubble Formation at a Plate Orifice

NASA Technical Reports Server (NTRS)

Webbon, Bruce W.; Buyevich, Yu A.

1995-01-01

A model of the dynamic regime of gas injection through a submerged plate orifice into an ideally wetting liquid is developed in the circumstance when successively detached bubbles may be regarded as independent objects. Two major factors favor bubble detachment: the buoyancy force and a force due to the momentum inflow into the bubble with injected gas. In normal and moderately reduced gravity, the first factor dominates. At relatively low flow rates, a growing bubble is modeled as a spherical segment touching the orifice perimeter during the whole period of its evolution till detachment. If the flow rate exceeds a critical value, another stage of bubble evolution occurs in which an almost spherical gas envelope is connected with the orifice by a nearly cylindrical gaseous stem that lengthens as the bubble rises above the plate. The bubble continues to grow until the gas supply through the stem is completely cut off, after which back flow of gas into the stem from the bubble becomes possible. In microgravity, the second factor prevails, and the latter stage is always present irrespective of the flow rate. However, the gas envelope rises and the stem lengthens very slowly. This difference in the underlying physical mechanisms provides for key properties of bubble growth and detachment being drastically different in appreciable and sufficiently reduced gravity. The frequency of bubble formation slightly decreases with and the detachment volume is almost proportional to the gas flow rate in the first case, in accordance with familiar relations. In the second case, the first variable is proportional to the flow rate whereas the second one is independent of it. Effects of other parameters, such as the orifice radius, gas and liquid densities, and surface tension are discussed.

12. Pulse Control Assisted Dynamical Decoupling in a Central Spin Model

Li, Zhao-Yan; Wei, Yong-Bo; Wang, Zhao-Ming; Gu, Yong-Jian; Li, Wen-Dong; Ma, Xiao-Ping

2017-02-01

We study pulse control assisted dynamical decoupling through a central spin model in a total Hilbert space. We find that the effective decoupling can be realized by applying a sequence of external pulses. Compared with the bang-bang control which needs infinite strength and infinitesimal short pulses, we show that there is a large parameter space that allows an effective nonperturbative dynamical control. Furthermore, our numerical calculation shows that the reliability can be held for random pulses, such as random pulse time interval or random strength.

13. Modelling of noise-like pulses generated in fibre lasers

Smirnov, Sergey; Kobtsev, Sergey

2016-03-01

The present paper for the first time proposes and studies a relatively simple model of noise-like pulses that matches the experimental data well and suggests that there is a correlation between phases of adjacent spectral components of noiselike pulses. Comparison of a relatively basic model of `random' pulses with the results of noise-like pulse modelling in mode-locked fibre lasers based on coupled non-linear Schrödinger equations demonstrates that it adequately reproduces temporal and spectral properties of noise-like pulses as well as correlation between adjacent modes so that it's possible to use the proposed model for highly efficient simulations of promising applications of noise-like pulses, such as material processing, non-linear frequency conversion, microscopy, and others.

14. Bubble Formation at a Submerged Orifice in Reduced Gravity

NASA Technical Reports Server (NTRS)

Buyevich, Yu A.; Webbon, Bruce W.

1994-01-01

The dynamic regime of gas injection through a circular plate orifice into an ideally wetting liquid is considered, when successively detached bubbles may be regarded as separate identities. In normal gravity and at relatively low gas flow rates, a growing bubble is modeled as a spherical segment touching the orifice perimeter during the whole time of its evolution. If the flow rate exceeds a certain threshold value, another stage of the detachment process takes place in which an almost spherical gas envelope is connected with the orifice by a nearly cylindrical stem that lengthens as the bubble rises above the plate. The bubble shape resembles then that of a mushroom and the upper envelope continues to grow until the gas supply through the stem is completely cut off. Such a stage is always present under conditions of sufficiently low gravity, irrespective of the flow rate. Two major reasons make for bubble detachment: the buoyancy force and the force due to the momentum inflow into the bubble with the injected gas. The former force dominates the process at normal gravity whereas the second one plays a key role under negligible gravity conditions. It is precisely this fundamental factor that conditions the drastic influence on bubble growth and detachment that changes in gravity are able to cause. The frequency of bubble formation is proportional to and the volume of detached bubbles is independent of the gas flow rate in sufficiently low gravity, while at normal and moderately reduced gravity conditions the first variable slightly decreases and the second one almost linearly increases as the flow rate grows. Effects of other parameters, such as the orifice radius, gas and liquid densities, and surface tension are discussed.

15. Effects of Ultrasmall Orifices on the Electro-generation of Femtoliter-Volume Aqueous Droplets

PubMed Central

He, Mingyan; Kuo, Jason S.; Chiu, Daniel T.

2008-01-01

The ability to generate individual picoliter- and femtoliter-volume aqueous droplets on-demand is useful for encapsulating and chemically manipulating discrete chemical and biological samples. This paper characterizes the effects of orifice dimensions and material choices on generating such droplets in an immiscible oil phase using single high-voltage pulses with various amplitudes and durations. We have examined microfluidic orifices as small as 1.7 μm in equivalent radii, and found that the electrohydrodynamic jet lengths and the subsequent formation of droplets are affected by the axial aspect ratios of the orifices (length of an orifice divided by its equivalent radius). As higher voltages were used to compensate for the increased capillary pressure and hydrodynamic resistance in ultrasmall orifices, we observed secondary jet protrusions and droplet formations that were not of classical electrohydrodynamic origin. The droplets generated from secondary jets traveled at relatively lower velocities as compared to those of electrohydrodynamic origin, and these slow individual droplets are potentially more useful for applications in microscale chemical reactions. PMID:16800707

16. Head loss coefficient through sharp-edged orifices

Adam, Nicolas J.; De Cesare, Giovanni; Schleiss, Anton J.; Richard, Sylvain; Muench-Alligné, Cécile

2016-11-01

Nowadays, high-head power plants could increase their installed power capacity for many reasons, e.g. dam heightening, increase of their peak power capacity or refurbishment with new turbines. Frequently, due to several considerations, e.g. topographical or economical limitations, the existing surge tank cannot be extended to keep previous safety levels and efficiency. A valuable way to adapt these surge tanks is to place a throttle at their entrance like, for example, an orifice. The main effect of this adaptation is the introduction of head losses that reduce the extreme levels in the surge tank due to the mass oscillations resulting from a closure or opening of downstream discharge control. This research studies the influence of the edge angle of a ASME-standard orifice on the head losses. This angle introduces an asymmetrical behavior and influences head losses. Different angles are tested from 0° to the 67° (biggest angle possible for this configuration). The first step of this study is to determine experimentally the steady losses produced by orifice for several discharges. In the second step, a numerical model on ANSYS CFX is performed. Combining the two approaches, it is possible to understand and quantify the effect of the edge angle.

17. On the attached length of orifices

Komkin, A. I.; Mironov, M. A.; Yudin, S. I.

2012-11-01

The attached length of orifices in reactive mufflers has been estimated based on numerical calculations by the finite-element method. The numerical results for a diaphragm in a duct are compared with the theoretical data obtained by Rayleigh, Fock, Karal, and Ingard. The dependence of the attached length on the diaphragm thickness is given. The results obtained are generalized for the case in which the orifice is a Helmholtz resonator neck. The effect of the resonator length on the attached length of the neck is analyzed.

18. The underground electromagnetic pulse: Four representative models

SciTech Connect

Wouters, L.F.

1989-06-01

I describe four phenomenological models by which an underground nuclear explosion may generate electromagnetic pulses: Compton current asymmetry (or ''Compton dipole''); Uphole conductor currents (or ''casing currents''); Diamagnetic cavity plasma (or ''magnetic bubble''); and Large-scale ground motion (or ''magneto-acoustic wave''). I outline the corresponding analytic exercises and summarize the principal results of the computations. I used a 10-kt contained explosion as the fiducial case. Each analytic sequence developed an equivalent source dipole and calculated signal waveforms at representative ground-surface locations. As a comparative summary, the Compton dipole generates a peak source current moment of about 12,000 A/center dot/m in the submicrosecond time domain. The casing-current source model obtains an equivalent peak moment of about 2 /times/ 10/sup 5/ A/center dot/m in the 10- to 30-/mu/s domain. The magnetic bubble produces a magnetic dipole moment of about 7 /times/ 10/sup 6/ A/center dot/m/sup 2/, characterized by a 30-ms time structure. Finally, the magneto-acoustic wave corresponds to a magnetic dipole moment of about 600 A/center dot/m/sup 2/, with a waveform showing 0.5-s periodicities. 8 refs., 35 figs., 7 tabs.

19. Measurements and computational fluid dynamics predictions of the acoustic impedance of orifices

Su, J.; Rupp, J.; Garmory, A.; Carrotte, J. F.

2015-09-01

The response of orifices to incident acoustic waves, which is important for many engineering applications, is investigated with an approach combining both experimental measurements and numerical simulations. This paper presents experimental data on acoustic impedance of orifices, which is subsequently used for validation of a numerical technique developed for the purpose of predicting the acoustic response of a range of geometries with moderate computational cost. Measurements are conducted for orifices with length to diameter ratios, L/D, of 0.5, 5 and 10. The experimental data is obtained for a range of frequencies using a configuration in which a mean (or bias) flow passes from a duct through the test orifices before issuing into a plenum. Acoustic waves are provided by a sound generator on the upstream side of the orifices. Computational fluid dynamics (CFD) calculations of the same configuration have also been performed. These have been undertaken using an unsteady Reynolds averaged Navier-Stokes (URANS) approach with a pressure based compressible formulation with appropriate characteristic based boundary conditions to simulate the correct acoustic behaviour at the boundaries. The CFD predictions are in very good agreement with the experimental data, predicting the correct trend with both frequency and orifice L/D in a way not seen with analytical models. The CFD was also able to successfully predict a negative resistance, and hence a reflection coefficient greater than unity for the L / D = 0.5 case.

20. Overcome side identification in PPOP by making orifices on both layers.

PubMed

Zhang, Zhi-hong; Li, Wei; Nie, Shu-fang; Tang, Xin; Peng, Bo; Tian, Lei; Pan, Wei-san

2009-04-17

The original purpose of this research was to build a database for an expert system. Unexpectedly, it was found that the color-identifying device in push-pull osmotic pump (PPOP) manufacturing process could be unnecessary. Water-insoluble drug indapamide, gliclazide and dipyridamole were employed as model drugs. Bunches of conventional formulations were designed; and traditional preparation procedures were used. In vitro drug release was studied; and the similarity between the conditions of orifice only on the side of the drug layer and orifices of the same diameter on both sides was evaluated. It was found that the drug release from PPOP could be influenced by formulation and core hardness while it could hardly be influenced by orifice size. No significant difference was observed between the dissolution profiles of orifice only on the side of the drug layer and orifices of the same diameter on both sides. Mechanism of drug release was discussed. The conclusion was that the disadvantage of side identification in PPOP manufacturing process could be overcome by drilling orifices on both sides.

1. Modeling propagation of coherent optical pulses through molecular vapor

SciTech Connect

Shore, B.W.; Eberly, J.H.

1982-01-01

Results of modeling the mutual coupling of coherent molecular response and coherent optical pulses during propagation are described. The propagation is treated numerically, with particular emphasis on both continuum and discrete behavior associated with the quasicontinuum model.

2. Variable orifice using an iris shutter

DOEpatents

Beeman, Raymond; Brajkovich, Steven J.

1978-01-01

A variable orifice forming mechanism utilizing an iris shutter arrangement adapted to control gas flow, conductance in vacuum systems, as a heat shield for furnace windows, as a beam shutter in sputtering operations, and in any other application requiring periodic or continuously-variable control of material, gas, or fluid flow.

3. Contoured Orifice for Silicon-Ribbon Die

NASA Technical Reports Server (NTRS)

Mackintosh, B. H.

1985-01-01

Die configuration encourages purity and stable growth. Contour of die orifice changes near ribbon edges. As result, silicon ribbon has nearly constant width and little carbon contamination. Die part of furnace being developed to produce high-quality, low-cost material for solar cells.

4. Update on Natural Orifice Translumenal Endoscopic Surgery

PubMed Central

Bingener, Juliane; Gostout, Christopher J.

2012-01-01

Natural orifice translumenal endoscopic surgery (NOTES) has moved from the realm of laboratory experiments to the realm of human clinical trials. This paper reviews the spectrum of NOTES procedures currently available in the United States and worldwide. It also discusses the limitations and avenues for further development of these procedures, particularly those involving the transgastric approach. PMID:22933874

5. Modeling of space-time focusing of localized nondiffracting pulses

Zamboni-Rached, Michel; Besieris, Ioannis M.

2016-10-01

In this paper we develop a method capable of modeling the space-time focusing of nondiffracting pulses. These pulses can possess arbitrary peak velocities and, in addition to being resistant to diffraction, can have their peak intensities and focusing positions chosen a priori. More specifically, we can choose multiple locations (spatial ranges) of space and time focalization; also, the pulse intensities can be chosen in advance. The pulsed wave solutions presented here can have very interesting applications in many different fields, such as free-space optical communications, remote sensing, medical apparatus, etc.

6. Mathematical modeling of the optimum pulse structure for safe and effective photo epilation using broadband pulsed light.

PubMed

Ash, Caerwyn; Donne, Kelvin; Daniel, Gwenaelle; Town, Godfrey; Clement, Marc; Valentine, Ronan

2012-09-06

The objective of this work is the investigation of intense pulsed light (IPL) photoepilation using Monte Carlo simulation to model the effect of the output dosimetry with millisecond exposure used by typical commercial IPL systems. The temporal pulse shape is an important parameter, which may affect the biological tissue response in terms of efficacy and adverse reactions. This study investigates the effect that IPL pulse structures, namely free discharge, square pulse, close, and spaced pulse stacking, has on hair removal. The relationship between radiant exposure distribution during the IPL pulse and chromophore heating is explored and modeled for hair follicles and the epidermis using a custom Monte Carlo computer simulation. Consistent square pulse and close pulse stacking delivery of radiant exposure across the IPL pulse is shown to generate the most efficient specific heating of the target chromophore, whilst sparing the epidermis, compared to free discharge and pulse stacking pulse delivery. Free discharge systems produced the highest epidermal temperature in the model. This study presents modeled thermal data of a hair follicle in situ, indicating that square pulse IPL technology may be the most efficient and the safest method for photoepilation. The investigation also suggests that the square pulse system design is the most efficient, as energy is not wasted during pulse exposure or lost through interpulse delay times of stacked pulses.

7. Pulse shape control in a dual cavity laser: numerical modeling

Yashkir, Yuri

2006-04-01

We present a numerical model of the laser system for generating a special shape of the pulse: a steep peak at the beginning followed by a long pulse tail. Laser pulses of this nature are required for various applications (laser material processing, optical breakdown spectroscopy, etc.). The laser system consists of two "overlapped" cavities with different round-trip times. The laser crystal, the Q-switching element, the back mirror, and the output coupler are shared. A shorter pulse is generated in a short cavity. A small fraction of this pulse is injected into the long cavity as a seed. It triggers generation of the longer pulse. The output emission from this hybrid laser produces a required pulse shape. Parameters of the laser pulse (ratios of durations and energies of short- and long- pulse components) can be controlled through cavity length and the output coupler reflection. Modelling of the laser system is based on a set of coupled rate equations for dynamic variables of the system: the inverse population in an active laser media and photon densities in coupled cavities. Numerical experiments were provided with typical parameters of a Nd:YAG laser to study the system behaviour for different combinations of parameters.

8. Pulsed thrust propellant reorientation - Concept and modeling

NASA Technical Reports Server (NTRS)

Hochstein, John I.; Patag, Alfredo E.; Korakianitis, T. P.; Chato, David J.

1992-01-01

The use of pulsed thrust to optimize the propellant reorientation process is proposed. The ECLIPSE code is used to study the performance of pulsed reorientation in small-scale and full-scale propellant tanks. A dimensional analysis of the process is performed and the resulting dimensionless groups are used to present and correlate the computational predictions of reorientation performance. Based on the results obtained from this study, it is concluded that pulsed thrust reorientation seems to be a feasible technique for optimizing the propellant reorientation process across a wide range of spacecraft, for a variety of missions, for the entire duration of a mission, and with a minimum of hardware design and qualification.

9. Cosine-Gaussian correlated Schell-model pulsed beams.

PubMed

Ding, Chaoliang; Korotkova, Olga; Zhang, Yongtao; Pan, Liuzhan

2014-01-13

A new class of partially coherent pulses of Schell type with cosine-Gaussian temporal degree of coherence is introduced. Such waves are termed the Cosine-Gaussian Schell-model (CGSM) pulses. The analytic expression for the temporal mutual coherence function of the CGSM pulse in dispersive media is derived and used to study the evolution of its intensity distribution and its temporal degree of coherence. Further, the numerical calculations are performed in order to show the dependence of the intensity profile and the temporal degree of coherence of the CGSM pulse on the incident pulse duration, the initial temporal coherence length, the order-parameter n and the dispersion of the medium. The most important feature of the novel pulsed wave is its ability to split into two pulses on passage in a dispersive medium at some critical propagation distance. Such critical distance and the subsequent evolution of the split pulses are shown to depend on the source parameters and on the properties of the medium in which the pulse travels.

10. Finite element modeling of pulsed eddy current NDT phenomena

SciTech Connect

Allen, B.; Ida, N.; Lord, W.

1985-05-15

Transient fields for nondestructive testing (pulsed eddy current methods) have been used experimentally for such applications as coating thickness measurements and the inspection of reactor fuel tubing. The lack of suitable models to facilitate understanding of the interaction of the pulsed field with the test specimen has hindered a wider acceptance of the method as a tool in NDT. Two models, based on the finite element technique are described. The first model, used for repetitive pulse train sources makes use of the Fourier series of the source current to solve a steady state problem for each significant harmonic. The harmonic solutions are then summed to produce the total EMF in the pickup coil. The second model is used for single pulse application. The response is calculated using an iterative time stepping solution. In both cases axisymmetric geometries are studied using a magnetic vector potential formulation. Solutions are compared with experimental results. 3 refs., 3 figs.

11. A pulse tube cryocooler with a cold reservoir

Zhang, X. B.; Zhang, K. H.; Qiu, L. M.; Gan, Z. H.; Shen, X.; Xiang, S. J.

2013-02-01

Phase difference between pressure wave and mass flow is decisive to the cooling capacity of regenerative cryocoolers. Unlike the direct phase shifting using a piston or displacer in conventional Stirling or GM cryocoolers, the pulse tube cyocooler (PTC) indirectly adjusts the cold phase due to the absence of moving parts at the cold end. The present paper proposed and validated theoretically and experimentally a novel configuration of PTC, termed cold reservoir PTC, in which a reservoir together with an adjustable orifice is connected to the cold end of the pulse tube. The impedance from the additional orifice to the cold end helps to increase the mass flow in phase with the pressure wave at the cold end. Theoretical analyses with the linear model for the orifice and double-inlet PTCs indicate that the cooling performance can be improved by introducing the cold reservoir. The preliminary experiments with a home-made single-stage GM PTC further validated the results on the premise of minor opening of the cold-end orifice.

12. Acoustic Absorption Characteristics of an Orifice With a Mean Bias Flow

NASA Technical Reports Server (NTRS)

Ahuja, K. K.; Gaeta, R. J., Jr.; DAgostino, M.; Jones, Mike (Technical Monitor)

2000-01-01

The objective of the study reported here was to acquire acoustic and flow data for numerical validation of impedance models that simulate bias flow through perforates. The impedance model is being developed by researchers at High Technology Corporation. This report documents normal incidence impedance measurements a singular circular orifice with mean flow passing through it. All measurements are made within a 1.12 inch (28.5 mm) diameter impedance tube. The mean flow is introduced upstream of the orifice (with the flow and incident sound wave travelling in the same direction) with an anechoic termination downstream of the orifice. Velocity profiles are obtained upstream of the orifice to characterize the inflow boundary conditions. Velocity in the center of the orifice is also obtained. All velocity measurements are made with a hot wire anemometer and subsequent checked with mass flow measurements made concurrently. All impedance measurements are made using the Two-Microphone Method. Although we have left the analysis of the data to the developers of the impedance models that simulate bias flow through perforate, our initial examination indicates that our results follow the trends consistent with published theory on impedance of perforates with a steady bias flow.

13. Experiments in dilution jet mixing effects of multiple rows and non-circular orifices

NASA Technical Reports Server (NTRS)

Holdeman, J. D.; Srinivasan, R.; Coleman, E. B.; Meyers, G. D.; White, C. D.

1985-01-01

Experimental and empirical model results are presented that extend previous studies of the mixing of single-sided and opposed rows of jets in a confined duct flow to include effects of non-circular orifices and double rows of jets. Analysis of the mean temperature data obtained in this investigation showed that the effects of orifice shape and double rows are significant only in the region close to the injection plane, provided that the orifices are symmetric with respect to the main flow direction. The penetration and mixing of jets from 45-degree slanted slots is slightly less than that from equivalent-area symmetric orifices. The penetration from 2-dimensional slots is similar to that from equivalent-area closely-spaced rows of holes, but the mixing is slower for the 2-D slots. Calculated mean temperature profiles downstream of jets from non-circular and double rows of orifices, made using an extension developed for a previous empirical model, are shown to be in good agreement with the measured distributions.

14. Effect of grazing flow on the acoustic impedance of Helmholtz resonators consisting of single and clustered orifices

NASA Technical Reports Server (NTRS)

Hersch, A. S.; Walker, B.

1979-01-01

A semiempirical fluid mechanical model is derived for the acoustic behavior of thin-walled single orifice Helmholtz resonators in a grazing flow environment. The incident and cavity sound fields are connected in terms of an orifice discharge coefficient whose values are determined experimentally using the two-microphone method. Measurements show that at high grazing flow speeds, acoustical resistance is almost linearly proportional to the grazing flow speed and almost independent of incident sound pressure. The corresponding values of reactance are much smaller and tend towards zero. For thicker-walled orifice plates, resistance and reactance were observed to be less sensitive to grazing flow as the ratio of plate thickness to orifice diameter increased. Loud tones were observed to radiate from a single orifice Helmholtz resonator due to interaction between the grazing flow shear layer and the resonator cavity. Measurements showed that the tones radiated at a Strouhal number equal to 0.26. The effects of grazing flow on the impedance of Helmholtz resonators consisting of clusters of orifices was also studied. In general, both resistance and reaction were found to be virtually independent of orifice relative spacing and number. These findings are valid with and without grazing flow.

15. Pulse

MedlinePlus

... the underside of the opposite wrist, below the base of the thumb. Press with flat fingers until ... determine if the patient's heart is pumping. Pulse measurement has other uses as well. During or immediately ...

16. A Simple Model of Pulsed Ejector Thrust Augmentation

NASA Technical Reports Server (NTRS)

Wilson, Jack; Deloof, Richard L. (Technical Monitor)

2003-01-01

A simple model of thrust augmentation from a pulsed source is described. In the model it is assumed that the flow into the ejector is quasi-steady, and can be calculated using potential flow techniques. The velocity of the flow is related to the speed of the starting vortex ring formed by the jet. The vortex ring properties are obtained from the slug model, knowing the jet diameter, speed and slug length. The model, when combined with experimental results, predicts an optimum ejector radius for thrust augmentation. Data on pulsed ejector performance for comparison with the model was obtained using a shrouded Hartmann-Sprenger tube as the pulsed jet source. A statistical experiment, in which ejector length, diameter, and nose radius were independent parameters, was performed at four different frequencies. These frequencies corresponded to four different slug length to diameter ratios, two below cut-off, and two above. Comparison of the model with the experimental data showed reasonable agreement. Maximum pulsed thrust augmentation is shown to occur for a pulsed source with slug length to diameter ratio equal to the cut-off value.

17. Modelling X-ray Pulse Profiles of Millisecond Pulsars

Leahy, D. A.; Morsink, S.; Tian, W.

2013-03-01

The modelling of X-ray pulse profiles from accreting millisecond pulsars is a way to infer masses and radii of neutron stars. We briefly describe how a pulse shape encodes information on the mass and radius, but also depends on other parameters such as hot spot location and observer viewing angle. A numerical model that we have developed is then described. The model includes light bending, time-delay effects, and Doppler effects for photons. The model accounts for oblateness of the neutron star, caused by the rapid rotation, and for scattered light from the surface of the accretion disk. The millisecond pulsar SAX J1808-3658 has multiple observations taken during different outbursts. The observed pulse shapes vary greatly, and it is a challenging test to fit the different observations. Some of the latest results are given.

18. Study of orifice fabrication technologies for the liquid droplet radiator

NASA Technical Reports Server (NTRS)

Wallace, David B.; Hayes, Donald J.; Bush, J. Michael

1991-01-01

Eleven orifice fabrication technologies potentially applicable for a liquid droplet radiator are discussed. The evaluation is focused on technologies capable of yielding 25-150 microns diameter orifices with trajectory accuracies below 5 milliradians, ultimately in arrays of up to 4000 orifices. An initial analytical screening considering factors such as trajectory accuracy, manufacturability, and hydrodynamics of orifice flow is presented. Based on this screening, four technologies were selected for experimental evaluation. A jet straightness system used to test 50-orifice arrays made by electro-discharge machining (EDM), Fotoceram, and mechanical drilling is discussed. Measurements on orifice diameter control and jet trajectory accuracy are presented and discussed. Trajectory standard deviations are in the 4.6-10.0 milliradian range. Electroforming and EDM appear to have the greatest potential for Liquid Droplet Radiator applications. The direction of a future development effort is discussed.

19. Mixing, ignition and combustion studies using discrete orifice injection at hypervelocity flight conditions

NASA Technical Reports Server (NTRS)

Bakos, R.; Tamagno, J.; Trucco, R.; Rizkalla, O.; Chinitz, W.

1991-01-01

Testing at hypervelocity test conditions continues in the Hypulse expansion tube. A newly-calibrated Mach 13 operating point has been achieved, and hydrogen injection studies were performed at this test condition. The experiments were conducted in a 2-in x 1-in combustor model employing three injector configurations: a single flush-wall circular orifice; two such orifices on opposite walls (the 'dual' injector configuration); and two orifices on the upper and the lower walls (the 'quad' injector configuration). The quad injectors were distinctly superior to the other two configurations in promoting mixing, ignition, and combustion. The single injector, however, proved to be superior to the dual injectors, supporting the concept that the aspect ratio of the 'injection cell' plays a large role in promoting the processes required to achieve high combustion efficiency.

20. Numerical investigation of the geometrical effects on UHMWPE flow characteristics in small aperture spinneret orifice

Qin, Shengxue; Zhang, Zhanhuan; Xu, Xingming; Liu, Jie; Liu, Hong

2015-07-01

Due to high viscosity of the ultra-high molecular weight polyethylene (UHMWPE), it is difficult for the melt UHMWPE to flow through the small aperture spinneret orifice in the melt spinning forming process. The geometrical parameters of the spinneret orifice become critical to the melt spinning process. Based on the theory of polymer rheology, the finite element model of UHMWPE melt spinning had been developed by using POLYFLOW, and the length-to-diameter ratio and taper angle of the spinneret orifice effects on the UHMWPE melt flow characters were discussed. The results show that suitable length-to-diameter ratio and taper angle are helpful for the compactness and flow stability of the melt.

1. Effect of orifice-area reduction on flow characteristics during injection through spinal needles.

PubMed

Myers, M R; Malinauskas, R A

1998-02-01

A reduction in hole size for certain side-port spinal needles has been advocated in recent reports. While the influence of orifice-area reduction on the aspiration capability of the needle has been studied, the influence on the anaesthetic delivery properties is relatively unknown. As a first step in understanding the effects of hole-size reduction on anaesthetic distribution within the subarachnoid space, we studied flows emanating from isolated needles using computer simulations. Following validation of the numerical model using experimental particle visualisation, trajectories of anaesthetic particles injected through 25 G Whitacre needles of various orifice areas were computed and used to determine the orientation and rate of spread of the anaesthetic jet exiting the needle. Two factors impacting the concentration distribution were observed: the rate of spread of the anaesthetic jet increases markedly with decreasing orifice area and the jet alignment shifts toward perpendicular to the needle axis.

2. A novel, new robotic platform for natural orifice distal pancreatectomy.

PubMed

Thakkar, Shyam; Awad, Michael; Gurram, Krishna C; Tully, Steven; Wright, Cornell; Sanan, Siddharth; Choset, Howie

2015-06-01

Laparoendoscopic technology has revolutionized the practice of surgery; however, surgeons have not widely accepted laparoscopic techniques for pancreatic surgeries due to the complexity of the operation. Natural orifice transluminal endoscopic surgery (NOTES) offers a great new potential for pancreatic procedures, with early data showing benefits of reduced visible scarring and the potential for decreased wound infections, hernias, pain, and postoperative complications. However, there are significant limitations to the currently used flexible endoscopy tools, including a diminished visual field, spatial orientation and tissue manipulation issues, and 2-dimensional visual feedback. We have adopted a novel snake-like robot, the minimally invasive cardiac surgery (MICS) robot, which addresses these issues. In the current pilot study, the MICS robot was evaluated for transrectal distal pancreas exploration and resection in 2 nonsurvival porcine models. Abdominal navigation and accessing the pancreas was investigated in the first pig, and based on its success, pancreas resection was studied in pig 2. The MICS robot was successful in accessing and visualizing the right upper, left upper, and left lower quadrants of the abdomen in pig 1 and was able to perform a successful complex NOTES procedure with distal pancreas resection in pig 2, with only minimal laparoscopic retraction assistance. In conclusion, preliminary results showing the MICS robot in natural orifice distal pancreatectomy are positive. Enhancements to optics and instrumentation will help further increase the usability in pancreatic interventions. Future indications may include transgastric NOTES approaches, endoluminal procedures, and single-port applications.

3. Transverse Injection into Subsonic Crossflow with Various Injector Orifice Geometries

NASA Technical Reports Server (NTRS)

Foster, Lancert E.; Zaman, Khairul B.

2010-01-01

Computational and experimental results are presented for a case study of single injectors employed in 90 deg transverse injection into a non-reacting subsonic flow. Different injector orifice shapes are used (including circular, square, diamond-shaped, and wide rectangular slot), all with constant cross-sectional area, to observe the effects of this variation on injector penetration and mixing. Whereas the circle, square, and diamond injector produce similar jet plumes, the wide rectangular slot produces a plume with less vertical penetration than the others. There is also some evidence that the diamond injector produces slightly faster penetration with less mixing of the injected fluid. In addition, a variety of rectangular injectors were analyzed, with varying length/width ratios. Both experimental and computational data show improved plume penetration with increased streamwise orifice length. 3-D Reynolds-Averaged Navier-Stokes (RANS) results are obtained for the various injector geometries using NCC (National Combustion Code) with the kappa-epsilon turbulence model in multi-species modes on an unstructured grid. Grid sensitivity results are also presented which indicate consistent qualitative trends in the injector performance comparisons with increasing grid refinement.

4. Drinking spout orifice size affects licking behavior in inbred mice.

PubMed

Dotson, Cedrick D; Spector, Alan C

2005-08-07

Using a lickometer, we assessed the effect of drinking spout orifice size on the licking behavior of inbred mice [C57BL/6J, SWR/J, 129P3/J and DBA/2J]. Animals licked from drinking spout sipper tubes that had what were defined as either a large (2.7 mm) or a small (1.5 mm) orifice. Mice took approximately twice as many licks from a stationary single small orifice drinking spout than when licking from a spout with a large orifice during separate 30-min sessions. However, their total intake volume was approximately the same. We calculated that mice received a mean of 0.55 muL per lick from the drinking tubes with a small orifice and a mean of 1.15 muL per lick from the drinking tubes with a large orifice. Thus, the animals appear to have regulated their fluid intake by proportionally adjusting their licking as a function of the lick volume. On average, this regulation occurred through modulation of the size of licking bursts and not their frequency. However, strain differences in compensation strategy were observed. When licking was restricted to a series of 5-s trials in a 30-min brief access test session, the smaller orifice size increased the range of responsiveness that was expressed. Mice increased their average licks per trial by 20% and took 60% more trials when licking from a spout with a small orifice. Interestingly, when the orifice size was quasi-randomly varied within a brief access session, licking was greater from large orifice drinking spouts, suggesting that water delivered from the two orifice sizes differs in its reinforcement efficacy. These findings demonstrate that drinking spout orifice size can significantly influence experimental outcomes in licking tests involving mice and care should be taken in controlling this variable in testing the effects of taste or other factors on ingestive behavior.

5. Gaseous Nitrogen Orifice Mass Flow Calculator

NASA Technical Reports Server (NTRS)

Ritrivi, Charles

2013-01-01

The Gaseous Nitrogen (GN2) Orifice Mass Flow Calculator was used to determine Space Shuttle Orbiter Water Spray Boiler (WSB) GN2 high-pressure tank source depletion rates for various leak scenarios, and the ability of the GN2 consumables to support cooling of Auxiliary Power Unit (APU) lubrication during entry. The data was used to support flight rationale concerning loss of an orbiter APU/hydraulic system and mission work-arounds. The GN2 mass flow-rate calculator standardizes a method for rapid assessment of GN2 mass flow through various orifice sizes for various discharge coefficients, delta pressures, and temperatures. The calculator utilizes a 0.9-lb (0.4 kg) GN2 source regulated to 40 psia (.276 kPa). These parameters correspond to the Space Shuttle WSB GN2 Source and Water Tank Bellows, but can be changed in the spreadsheet to accommodate any system parameters. The calculator can be used to analyze a leak source, leak rate, gas consumables depletion time, and puncture diameter that simulates the measured GN2 system pressure drop.

6. Dielectrophoresis-assisted massively parallel cell pairing and fusion based on field constriction created by a micro-orifice array sheet.

PubMed

Kimura, Yuji; Gel, Murat; Techaumnat, Boonchai; Oana, Hidehiro; Kotera, Hidetoshi; Washizu, Masao

2011-09-01

In this paper, we present a novel electrofusion device that enables massive parallelism, using an electrically insulating sheet having a two-dimensional micro-orifice array. The sheet is sandwiched by a pair of micro-chambers with immersed electrodes, and each chamber is filled with the suspensions of the two types of cells to be fused. Dielectrophoresis, assisted by sedimentation, is used to position the cells in the upper chamber down onto the orifices, then the device is flipped over to position the cells on the other side, so that cell pairs making contact in the orifice are formed. When a pulse voltage is applied to the electrodes, most voltage drop occurs around the orifice and impressed on the cell membrane in the orifice. This makes possible the application of size-independent voltage to fuse two cells in contact at all orifices exclusively in 1:1 manner. In the experiment, cytoplasm of one of the cells is stained with a fluorescence dye, and the transfer of the fluorescence to the other cell is used as the indication of fusion events. The two-dimensional orifice arrangement at the pitch of 50 μm realizes simultaneous fusion of 6 × 10³ cells on a 4 mm diameter chip, and the fusion yield of 78-90% is achieved for various sizes and types of cells.

7. State dependent model predictive control for orbital rendezvous using pulse-width pulse-frequency modulated thrusters

Li, Peng; Zhu, Zheng H.; Meguid, S. A.

2016-07-01

This paper studies the pulse-width pulse-frequency modulation based trajectory planning for orbital rendezvous and proximity maneuvering near a non-cooperative spacecraft in an elliptical orbit. The problem is formulated by converting the continuous control input, output from the state dependent model predictive control, into a sequence of pulses of constant magnitude by controlling firing frequency and duration of constant-magnitude thrusters. The state dependent model predictive control is derived by minimizing the control error of states and control roughness of control input for a safe, smooth and fuel efficient approaching trajectory. The resulting nonlinear programming problem is converted into a series of quadratic programming problem and solved by numerical iteration using the receding horizon strategy. The numerical results show that the proposed state dependent model predictive control with the pulse-width pulse-frequency modulation is able to effectively generate optimized trajectories using equivalent control pulses for the proximity maneuvering with less energy consumption.

8. Measurement and modeling of pulsed microchannel plate operation (invited).

PubMed

Rochau, G A; Wu, M; Kruschwitz, C; Joseph, N; Moy, K; Bailey, J; Krane, M; Thomas, R; Nielsen, D; Tibbitts, A

2008-10-01

Microchannel plates (MCPs) are a standard detector for fast-framing x-ray imaging and spectroscopy of high-temperature plasmas. The MCP is coated with conductive striplines that carry short duration voltage pulses to control the timing and amplitude of the signal gain. This gain depends on the voltage to a large exponent so that small reflections or impedance losses along the striplines can have a significant impact on the position-dependent amplitude and pulse width of the gain. Understanding the pulsed gain response therefore requires careful measurements of the position- and time-dependent surface voltage coupled with detailed modeling of the resulting electron cascade. We present measurements and modeling of the time- and space-dependent gain response of MCP detectors designed for use at Sandia National Laboratories' Z facility. The pulsed gain response is understood through measurements using a high impedence probe to determine the voltage pulse propagating along the stripline surface. Coupling the surface voltage measurements with Monte Carlo calculations of the electron cascade in the MCP provides a prediction of the time- and position-dependent gain that agrees with measurements made on a subpicosecond UV laser source to within the 25% uncertainty in the simulations.

9. A simple expression for pressure drops of water and other low molecular liquids in the flow through micro-orifices

Hasegawa, Tomiichi; Ushida, Akiomi; Narumi, Takatsune

2015-12-01

Flows are generally divided into two types: shear flows and shear-free elongational (extensional) flows. Both are necessary for a thorough understanding of the flow properties of a fluid. Shear flows are easy to achieve in practice, for example, through Poiseuille or Couette flows. Shear-free elongational flows are experimentally hard to achieve, resulting in an incomplete understanding of the flow properties of fluids in micro-devices. Nevertheless, flows through micro-orifices are useful for probing the properties of elongational flows at high elongational rates; although these flows exhibit shear and elongation, the elongation is dominant and the shear is negligible in the central region of the flows. We previously reported an anomalous reduction in pressure drops in the flows of water, a 50/50 mixture of glycerol and water, and silicone oils through micro-orifices. In the present paper, we rearrange the data presented in the previous paper and reveal a simple relationship where the pressure drop is proportional to the velocity through the micro-orifices, independent of the orifice diameter and the viscosity of the liquids tested. We explain our observations by introducing a "fluid element" model, in which fluid elements are formed on entering the orifice. The model is based on the idea that low molecular liquids, including water, generate strong elongational stress, similar to a polymer solution, in the flow through micro-orifices.

10. Quasi-One-Dimensional Modeling of Pulse Detonation Rocket Engines

NASA Technical Reports Server (NTRS)

Morris, Christopher I.

2003-01-01

Pulse detonation rocket engines (PDREs) offer potential performance improvements over conventional designs, but represent a challenging modeling task. A quasi 1-D, finite-rate chemistry CFD model for a PDRE & described and implemented. A parametric study of the effect of blowdown pressure ratio on the performance of an optimized, fixed PDRE nozzle configuration is reported. The results are compared to a steady-state rocket system using similar modeling assumptions.

11. Wind tunnel investigation of an all flush orifice air data system for a large subsonic aircraft. [conducted in a Langley 8 foot transonic pressure tunnel

NASA Technical Reports Server (NTRS)

Larson, T. J.; Flechner, S. G.; Siemers, P. M., III

1980-01-01

The results of a wind tunnel investigation on an all flush orifice air data system for use on a KC-135A aircraft are presented. The investigation was performed to determine the applicability of fixed all flush orifice air data systems that use only aircraft surfaces for orifices on the nose of the model (in a configuration similar to that of the shuttle entry air data system) provided the measurements required for the determination of stagnation pressure, angle of attack, and angle of sideslip. For the measurement of static pressure, additional flush orifices in positions on the sides of the fuselage corresponding to those in a standard pitot-static system were required. An acceptable but less accurate system, consisting of orifices only on the nose of the model, is defined and discussed.

12. Modeling of the bipolar transistor under different pulse ionizing radiations

Antonova, A. M.; Skorobogatov, P. K.

2017-01-01

This paper describes a 2D model of the bipolar transistor 2T312 under gamma, X-ray and laser pulse ionizing radiations. Both the Finite Element Discretization and Semiconductor module of Comsol 5.1 are used. There is an analysis of energy deposition in this device under different radiations and the results of transient ionizing current response for some different conditions.

13. Numerical Modeling of Pulse Detonation Rocket Engine Gasdynamics and Performance

NASA Technical Reports Server (NTRS)

Morris, C. I.

2003-01-01

Pulse detonation engines (PDB) have generated considerable research interest in recent years as a chemical propulsion system potentially offering improved performance and reduced complexity compared to conventional gas turbines and rocket engines. The detonative mode of combustion employed by these devices offers a theoretical thermodynamic advantage over the constant-pressure deflagrative combustion mode used in conventional engines. However, the unsteady blowdown process intrinsic to all pulse detonation devices has made realistic estimates of the actual propulsive performance of PDES problematic. The recent review article by Kailasanath highlights some of the progress that has been made in comparing the available experimental measurements with analytical and numerical models.

14. Quantum model for mode locking in pulsed semiconductor quantum dots

Beugeling, W.; Uhrig, Götz S.; Anders, Frithjof B.

2016-12-01

Quantum dots in GaAs/InGaAs structures have been proposed as a candidate system for realizing quantum computing. The short coherence time of the electronic quantum state that arises from coupling to the nuclei of the substrate is dramatically increased if the system is subjected to a magnetic field and to repeated optical pulsing. This enhancement is due to mode locking: oscillation frequencies resonant with the pulsing frequencies are enhanced, while off-resonant oscillations eventually die out. Because the resonant frequencies are determined by the pulsing frequency only, the system becomes immune to frequency shifts caused by the nuclear coupling and by slight variations between individual quantum dots. The effects remain even after the optical pulsing is terminated. In this work, we explore the phenomenon of mode locking from a quantum mechanical perspective. We treat the dynamics using the central-spin model, which includes coupling to 10-20 nuclei and incoherent decay of the excited electronic state, in a perturbative framework. Using scaling arguments, we extrapolate our results to realistic system parameters. We estimate that the synchronization to the pulsing frequency needs time scales in the order of 1 s .

15. Porous plug for reducing orifice induced pressure error in airfoils

NASA Technical Reports Server (NTRS)

Plentovich, Elizabeth B. (Inventor); Gloss, Blair B. (Inventor); Eves, John W. (Inventor); Stack, John P. (Inventor)

1988-01-01

A porous plug is provided for the reduction or elimination of positive error caused by the orifice during static pressure measurements of airfoils. The porous plug is press fitted into the orifice, thereby preventing the error caused either by fluid flow turning into the exposed orifice or by the fluid flow stagnating at the downstream edge of the orifice. In addition, the porous plug is made flush with the outer surface of the airfoil, by filing and polishing, to provide a smooth surface which alleviates the error caused by imperfections in the orifice. The porous plug is preferably made of sintered metal, which allows air to pass through the pores, so that the static pressure measurements can be made by remote transducers.

16. Effect of nonsymmetrical flow resistance upon orifice impedance

NASA Technical Reports Server (NTRS)

Posey, J. W.; Compton, K. J.

1974-01-01

Previous laboratory work has indicated that an orifice in a thin sheet behaves in a quasisteady manner under acoustical excitation. Also, it has been found that the steady flow resistance of an orifice may be dependent upon the direction of flow, especially in the presence of a crossflow on one side of the hole. An analytical study is presented which assumes a nonreactive orifice in an infinite baffle. The pressure difference across the orifice varies sinusoidally with amplitude 1.0 and average value -P. The orifice resistance is discontinuous at zero velocity and exhibits the constant values when the velocity is nonzero. The resultant velocity has power in all harmonics of the excitation frequency, providing an explanation of the even harmonic excitation observed by other investigators, but not predicted by symmetric nonlinearity. A quasilinear resistance is defined and found to be relatively insensitive to the presence or absence of a resonant backing cavity.

17. Use of nose cap and fuselage pressure orifices for determination of air data for space shuttle orbiter below supersonic speeds

NASA Technical Reports Server (NTRS)

Larson, T. J.; Siemers, P. M., III

1980-01-01

Wind tunnel pressure measurements were acquired from orifices on a 0.1 scale forebody model of the space shuttle orbiter that were arranged in a preliminary configuration of the shuttle entry air data system (SEADS). Pressures from those and auxiliary orifices were evaluated for their ability to provide air data at subsonic and transonic speeds. The orifices were on the vehicle's nose cap and on the sides of the forebody forward of the cabin. The investigation covered a Mach number range of 0.25 to 1.40 and an angle of attack range from 4 deg. to 18 deg. An air data system consisting of nose cap and forebody fuselage orifices constitutes a complete and accurate air data system at subsonic and transonic speeds. For Mach numbers less than 0.80 orifices confined to the nose cap can be used as a complete and accurate air data system. Air data systems that use only flush pressure orifices can be used to determine basic air data on other aircraft at subsonic and transonic speeds.

18. Experimental Validation of a Pulse Tube Cfd Model

Taylor, R. P.; Nellis, G. F.; Klein, S. A.; Radebaugh, R.; Lewis, M.; Bradley, P.

2010-04-01

Computational fluid dynamic (CFD) analysis has been applied by various authors to study the processes occurring in the pulse tube cryocooler and carry out parametric design and optimization. However, a thorough and quantitative validation of the CFD model predications against experimental data has not been accomplished. This is in part due to the difficulty associated with measuring the specific quantities of interest (e.g., internal enthalpy flows and acoustic power) rather than generic system performance (e.g., cooling power). This paper presents the experimental validation of a previously published two-dimensional, axisymmetric CFD model of the pulse tube and its associated flow transitions. The test facility designed for this purpose is unique in that it allows the precise measurement of the cold end acoustic power, regenerator loss, and cooling power. Therefore, it allows the separate and precise measurement of both the pulse tube loss and the regenerator loss. The experimental results are presented for various pulse tube and flow transition configurations operating at a cold end temperature of 80 K over a range of pressure ratios. The comparison of the model prediction to the experimental data is presented with discussion.

19. Modeling the pressure pulse shape of piezoelectric lithotripters

Dreyer, Thomas; Riedlinger, Rainer

2002-11-01

Piezoelectric focusing transducers are widely used in extracorporeal lithotripsy. To optimize the therapeutically relevant focal pressure pulse it is necessary to affect the generated pulse shape at the transducer surface. Therefore a modeling approach is required containing the acousto-mechanical properties of the transducer structure as well as the influence of the electrical drive. The procedure presented here uses three dimensional transient finite element simulations to calculate an electro-acoustical impulse response of the transducer structure and linear systems theory to model the influence of the driving circuit on the emitted acoustical signal. Applying a short electrical pulse an acoustical impulse response can be simulated under plane wave conditions, which is valid at sufficiently large distances from the transducer. Focal pressures are estimated rapidly by linear calculations or accurately by a nonlinear propagation model. The influence of electrical drive conditions on the emitted acoustical signal is investigated very efficiently by a convolution with the desired electrical input, avoiding FEM simulations for each case. Reverting this process the required driving voltage course for a given pressure signal is determined. Alterations of the pressure signal in terms of pulse width and tensile components are demonstrated theoretically, varying the design parameters of the transducer.

20. Stalled Pulsing Inertial Oscillation Model for a Tornadic Cyclone

NASA Technical Reports Server (NTRS)

Costen, Robert C.

2005-01-01

A supercell storm is a tall, rotating thunderstorm that can generate hail and tornadoes. Two models exist for the development of the storm's rotation or mesocyclone - the conventional splitting-storm model, and the more recent pulsing inertial oscillation (PIO) model, in which a nonlinear pulse represents the supercell. Although data support both models and both could operate in the same supercell, neither model has satisfactorily explained the tornadic cyclone. A tornadic cyclone is an elevated vorticity concentration of Rossby number approximately 1000 that develops within the contracting mesocyclone shortly before a major tornado appears at the surface. We now show that if the internal temperature excess due to latent energy release is limited to the realistic range of -12 K to +12 K, the PIO model can stall part way through the pulse in a state of contraction and spin-up. Should this happen, the stalled-PIO model can evolve into a tornadic cyclone with a central pressure deficit that exceeds 40 mb, which is greater than the largest measured value. This simulation uses data from a major tornadic supercell that occurred over Oklahoma City, Oklahoma, USA, on May 3, 1999. The stalled-PIO mechanism also provides a strategy for human intervention to retard or reverse the development of a tornadic cyclone and its pendant tornado.

1. Air suspension characterisation and effectiveness of a variable area orifice

Alonso, A.; Giménez, J. G.; Nieto, J.; Vinolas, J.

2010-12-01

The air spring is one of the components that most affects vehicle comfort. This element usually makes up the main part of the secondary suspension, which introduces both stiffness and damping between the bogie and the car body. Therefore, a deep understanding of this element is necessary in order to study the comfort of a vehicle, the influence of different parameters and the ways to improve it. In this work, the effect of the air spring system on comfort is studied. To accomplish this, a typical pneumatic suspension composition is briefly studied as a first step. Then, the test bench developed to characterise air springs is described, presenting experimental results. Correlation of the results with some theoretical models is also addressed. Afterwards, the effect of the air spring system on comfort is analysed, and finally, improvements from introducing a variable area orifice in the pipe that joints the air spring and the surge reservoir are discussed.

2. Computational modeling of ultra-short-pulse ablation of enamel

SciTech Connect

London, R.A.; Bailey, D.S.; Young, D.A.

1996-02-29

A computational model for the ablation of tooth enamel by ultra-short laser pulses is presented. The role of simulations using this model in designing and understanding laser drilling systems is discussed. Pulses of duration 300 sec and intensity greater than 10{sup 12} W/cm{sup 2} are considered. Laser absorption proceeds via multi-photon initiated plasma mechanism. The hydrodynamic response is calculated with a finite difference method, using an equation of state constructed from thermodynamic functions including electronic, ion motion, and chemical binding terms. Results for the ablation efficiency are presented. An analytic model describing the ablation threshold and ablation depth is presented. Thermal coupling to the remaining tissue and long-time thermal conduction are calculated. Simulation results are compared to experimental measurements of the ablation efficiency. Desired improvements in the model are presented.

3. Use of groundwater levels with the PULSE analytical model.

PubMed

Rutledge, Albert T

2014-01-01

The PULSE analytical model, which calculates daily groundwater discharge on the basis of user-specified recharge, was originally developed for calibration using streamflow data. This article describes a model application in which groundwater level data constitute the primary control on model input. As a test case, data were analyzed from a small basin in central Pennsylvania in which extensive groundwater level data are available. The timing and intensity of daily water-level rises are used to ascertain temporal distribution of recharge, and the simulated groundwater discharge hydrograph has shape features that are similar to the streamflow hydrograph. This article does not include details about calibration, but some steps are illustrated and general procedures are described for calibration in specific hydrologic studies. The PULSE model can be used to assess results of fully automated base flow methods and can be used to define groundwater recharge and discharge at a relatively small time scale.

4. Advanced modeling techniques in application to plasma pulse treatment

Pashchenko, A. F.; Pashchenko, F. F.

2016-06-01

Different approaches considered for simulation of plasma pulse treatment process. The assumption of a significant non-linearity of processes in the treatment of oil wells has been confirmed. Method of functional transformations and fuzzy logic methods suggested for construction of a mathematical model. It is shown, that models, based on fuzzy logic are able to provide a satisfactory accuracy of simulation and prediction of non-linear processes observed.

5. Modelling Multi-Pulse Population Dynamics from Ultrafast Spectroscopy

PubMed Central

van Wilderen, Luuk J. G. W.; Lincoln, Craig N.; van Thor, Jasper J.

2011-01-01

Current advanced laser, optics and electronics technology allows sensitive recording of molecular dynamics, from single resonance to multi-colour and multi-pulse experiments. Extracting the occurring (bio-) physical relevant pathways via global analysis of experimental data requires a systematic investigation of connectivity schemes. Here we present a Matlab-based toolbox for this purpose. The toolbox has a graphical user interface which facilitates the application of different reaction models to the data to generate the coupled differential equations. Any time-dependent dataset can be analysed to extract time-independent correlations of the observables by using gradient or direct search methods. Specific capabilities (i.e. chirp and instrument response function) for the analysis of ultrafast pump-probe spectroscopic data are included. The inclusion of an extra pulse that interacts with a transient phase can help to disentangle complex interdependent pathways. The modelling of pathways is therefore extended by new theory (which is included in the toolbox) that describes the finite bleach (orientation) effect of single and multiple intense polarised femtosecond pulses on an ensemble of randomly oriented particles in the presence of population decay. For instance, the generally assumed flat-top multimode beam profile is adapted to a more realistic Gaussian shape, exposing the need for several corrections for accurate anisotropy measurements. In addition, the (selective) excitation (photoselection) and anisotropy of populations that interact with single or multiple intense polarised laser pulses is demonstrated as function of power density and beam profile. Using example values of real world experiments it is calculated to what extent this effectively orients the ensemble of particles. Finally, the implementation includes the interaction with multiple pulses in addition to depth averaging in optically dense samples. In summary, we show that mathematical modelling is

6. Pulsed pumping process optimization using a potential flow model.

PubMed

Tenney, C M; Lastoskie, C M

2007-08-15

A computational model is applied to the optimization of pulsed pumping systems for efficient in situ remediation of groundwater contaminants. In the pulsed pumping mode of operation, periodic rather than continuous pumping is used. During the pump-off or trapping phase, natural gradient flow transports contaminated groundwater into a treatment zone surrounding a line of injection and extraction wells that transect the contaminant plume. Prior to breakthrough of the contaminated water from the treatment zone, the wells are activated and the pump-on or treatment phase ensues, wherein extracted water is augmented to stimulate pollutant degradation and recirculated for a sufficient period of time to achieve mandated levels of contaminant removal. An important design consideration in pulsed pumping groundwater remediation systems is the pumping schedule adopted to best minimize operational costs for the well grid while still satisfying treatment requirements. Using an analytic two-dimensional potential flow model, optimal pumping frequencies and pumping event durations have been investigated for a set of model aquifer-well systems with different well spacings and well-line lengths, and varying aquifer physical properties. The results for homogeneous systems with greater than five wells and moderate to high pumping rates are reduced to a single, dimensionless correlation. Results for heterogeneous systems are presented graphically in terms of dimensionless parameters to serve as an efficient tool for initial design and selection of the pumping regimen best suited for pulsed pumping operation for a particular well configuration and extraction rate. In the absence of significant retardation or degradation during the pump-off phase, average pumping rates for pulsed operation were found to be greater than the continuous pumping rate required to prevent contaminant breakthrough.

7. Computer modeling of pulsed CO2 lasers for lidar applications

NASA Technical Reports Server (NTRS)

Spiers, Gary D.

1993-01-01

The object of this effort is to develop code to enable the accurate prediction of the performance of pulsed transversely excited (TE) CO2 lasers prior to their construction. This is of particular benefit to the NASA Laser Atmospheric Wind Sounder (LAWS) project. A benefit of the completed code is that although developed specifically for the pulsed CO2 laser much of the code can be modified to model other laser systems of interest to the lidar community. A Boltzmann equation solver has been developed which enables the electron excitation rates for the vibrational levels of CO2 and N2, together with the electron ionization and attachment coefficients to be determined for any CO2 laser gas mixture consisting of a combination of CO2, N2, CO, He and CO. The validity of the model has been verified by comparison with published material. The results from the Boltzmann equation solver have been used as input to the laser kinetics code which is currently under development. A numerical code to model the laser induced medium perturbation (LIMP) arising from the relaxation of the lower laser level has been developed and used to determine the effect of LIMP on the frequency spectrum of the LAWS laser output pulse. The enclosed figures show representative results for a laser operating at 0.5 atm. with a discharge cross-section of 4.5 cm to produce a 20 J pulse with aFWHM of 3.1 microns. The first four plots show the temporal evolution of the laser pulse power, energy evolution, LIMP frequency chirp and electric field magnitude. The electric field magnitude is taken by beating the calculated complex electric field and beating it with a local oscillator signal. The remaining two figures show the power spectrum and energy distribution in the pulse as a function of the varying pulse frequency. The LIMP theory has been compared with experimental data from the NOAA Windvan Lidar and has been found to be in good agreement.

8. Orifice-induced pressure error studies in Langley 7- by 10-foot high-speed tunnel

NASA Technical Reports Server (NTRS)

Plentovich, E. B.; Gloss, B. B.

1986-01-01

For some time it has been known that the presence of a static pressure measuring hole will disturb the local flow field in such a way that the sensed static pressure will be in error. The results of previous studies aimed at studying the error induced by the pressure orifice were for relatively low Reynolds number flows. Because of the advent of high Reynolds number transonic wind tunnels, a study was undertaken to assess the magnitude of this error at high Reynolds numbers than previously published and to study a possible method of eliminating this pressure error. This study was conducted in the Langley 7- by 10-Foot High-Speed Tunnel on a flat plate. The model was tested at Mach numbers from 0.40 to 0.72 and at Reynolds numbers from 7.7 x 1,000,000 to 11 x 1,000,000 per meter (2.3 x 1,000,000 to 3.4 x 1,000,000 per foot), respectively. The results indicated that as orifice size increased, the pressure error also increased but that a porous metal (sintered metal) plug inserted in an orifice could greatly reduce the pressure error induced by the orifice.

9. Computer modeling of pulsed CO2 lasers for lidar applications

NASA Technical Reports Server (NTRS)

Spiers, Gary D.; Smithers, Martin E.; Murty, Rom

1991-01-01

The experimental results will enable a comparison of the numerical code output with experimental data. This will ensure verification of the validity of the code. The measurements were made on a modified commercial CO2 laser. Results are listed as following. (1) The pulse shape and energy dependence on gas pressure were measured. (2) The intrapulse frequency chirp due to plasma and laser induced medium perturbation effects were determined. A simple numerical model showed quantitative agreement with these measurements. The pulse to pulse frequency stability was also determined. (3) The dependence was measured of the laser transverse mode stability on cavity length. A simple analysis of this dependence in terms of changes to the equivalent fresnel number and the cavity magnification was performed. (4) An analysis was made of the discharge pulse shape which enabled the low efficiency of the laser to be explained in terms of poor coupling of the electrical energy into the vibrational levels. And (5) the existing laser resonator code was changed to allow it to run on the Cray XMP under the new operating system.

10. Heating model for metals irradiated by a subpicosecond laser pulse

Chimier, B.; Tikhonchuk, V. T.; Hallo, L.

2007-05-01

We propose a model describing the heating and ablation of a metallic target irradiated by a subpicosecond laser pulse. It takes into account the temperature equilibration between the electrons and ions and the density variation of the target material during the heating process. A simple analytical equation of state is developed, which allows one to calculate the total pressure in the heated layer for different electron and ion temperatures. The thermodynamic behavior of a nonequilibrium system is discussed, and nonequilibrium spinodals and cohesion limits are introduced. The model is applied for a description of the thermal ablation process driven by a sub-ps laser pulse. Aluminum and copper targets are considered, and it is shown that the dominant ablation process is due to breaking the nonequilibrium cohesion limit. The numerical results are in good agreement with recent experimental data.

11. Modeling of Multi-Tube Pulse Detonation Engine Operation

NASA Technical Reports Server (NTRS)

Ebrahimi, Houshang B.; Mohanraj, Rajendran; Merkle, Charles L.

2001-01-01

The present paper explores some preliminary issues concerning the operational characteristics of multiple-tube pulsed detonation engines (PDEs). The study is based on a two-dimensional analysis of the first-pulse operation of two detonation tubes exhausting through a common nozzle. Computations are first performed to assess isolated tube behavior followed by results for multi-tube flow phenomena. The computations are based on an eight-species, finite-rate transient flow-field model. The results serve as an important precursor to understanding appropriate propellant fill procedures and shock wave propagation in multi-tube, multi-dimensional simulations. Differences in behavior between single and multi-tube PDE models are discussed, The influence of multi-tube geometry and the preferred times for injecting the fresh propellant mixture during multi-tube PDE operation are studied.

12. Double-orifice mitral valve treated by percutaneous balloon valvuloplasty.

PubMed

Varghese, Thomas George; Revankar, Vinod Raghunath; Papanna, Monica; Srinivasan, Harshini

2016-07-01

Double-orifice mitral valve is an rare anomaly characterized by a mitral valve with a single fibrous annulus and 2 orifices that open into the left ventricle. It is often associated with other congenital anomalies, most commonly atrioventricular canal defects, and rarely associated with a stenotic or regurgitant mitral valve. A patient who was diagnosed with congenital double-orifice mitral valve with severe mitral stenosis was treated successfully by percutaneous balloon mitral valvotomy rather than the conventional open surgical approach, demonstrating the utility of percutaneous correction of this anomaly.

13. Pressure atomizer having multiple orifices and turbulent generation feature

DOEpatents

VanBrocklin, Paul G.; Geiger, Gail E.; Moran, Donald James; Fournier, Stephane

2002-01-01

A pressure atomizer includes a silicon plate having a top surface and a bottom surface. A portion of the top surface defines a turbulent chamber. The turbulent chamber is peripherally bounded by the top surface of the plate. The turbulent chamber is recessed a predetermined depth relative to the top surface. The silicon plate further defines at least one flow orifice. Each flow orifice extends from the bottom surface of the silicon plate to intersect with and open into the turbulent chamber. Each flow orifice is in fluid communication with the turbulent chamber.

14. Modeling of Pulses in Terrestrial Gamma-ray Flashes

Xu, Wei; Celestin, Sebastien; Pasko, Victor

2015-04-01

Terrestrial Gamma-ray Flashes (TGFs) are high-energy photon bursts originating from the Earth's atmosphere that are associated with lightning activities. After their discovery in 1994 by the Burst and Transient Source Experiment (BATSE) detector aboard the Compton Gamma-Ray Observatory [Fishman et al., Science, 264, 1313, 1994], this phenomenon has been further observed by the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) [Smith et al., Science, 307, 1085, 2005], the Fermi Gamma-ray Space Telescope [Briggs et al., JGR, 115, A07323, 2010] and the Astrorivelatore Gamma a Immagini Leggero (AGILE) satellite [Marisaldi et al., JGR, 115, A00E13, 2010]. Photon spectra corresponding to the mechanism of relativistic runaway electron avalanches (RREAs) usually provide a very good agreement with satellite observations [Dwyer and Smith, GRL, 32, L22804, 2005]. On the other hand, Celestin and Pasko [JGR, 116, A03315, 2011] have shown theoretically that the large flux of thermal runaway electrons generated by streamers during the negative corona flash stage of stepping lightning leaders in intracloud lightning flashes could be responsible for TGFs. Recently, based on analysis of the temporal profiles of 278 TGF events observed by the Fermi Gamma-Ray Burst Monitor, Foley et al. [JGR, 119, 5931, 2014] have suggested that 67% of TGF pulses detected are asymmetric and these asymmetric pulses are consistent with the production mechanism of TGFs by relativistic feedback discharges. In the present work, we employ a Monte Carlo model to study the temporal distribution of photons at low-orbit satellite altitudes during TGF events. Using the pulse fitting method described in [Foley et al., 2014], we further investigate the characteristics of TGF pulses. We mainly focus on the effects of Compton scattering on the symmetry properties and the rise and fall times of TGF pulses.

15. Assessment of simulation-based calibration of rectangular pulse models

Vanhaute, Willem Jan; Vandenberghe, Sander; Willems, Patrick; Verhoest, Niko E. C.

2013-04-01

The use of stochastic rainfall models has become widespread in many hydrologic applications, especially when historical rainfall records lack in length or quality to be used for practical purposes. Among a variety of models, rectangular pulse models such as the Neyman-scott and Bartlett-Lewis type models are known for their parsimonious nature and relative ease in simulating long rainfall time series. The aforementioned models are often calibrated using the generalized method of moments which fits modeled to observed moments. To ease the computational burden, the expected values of the modeled moments are usually expressed in function of the model parameters through analytical expressions. The derivation of such analytical expressions is considered to be an important bottleneck in the development of these rectangular pulse models. Any adjustment to the model structure must be accompanied by an adjustment of the analytical moments in order to be able to calibrate the adjusted model. To avoid the use of analytical moments during calibration, a simulation-based calibration is needed. The latter would enable the modeler to make and validate adjustments in a more organic matter. However, such simulation-based calibration must be able to account for the randomness of the simulation. As such, ensemble runs must be made for every objective function evaluation, resulting in considerable computational requirements. The presented research investigates how to exploit today's available computational resources in order to enable simulation-based calibration. Once such type of calibration is feasible, it will open doors to implementing adjustments to the model structure (such as the introduction of dependencies between model variables by using copulas) without the need to rely on analytical expressions of the different moments.

16. 49 CFR 230.71 - Orifice testing of compressors.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Compressor size Single strokes per minute Diameter of orifice(in inches) Air pressure maintained(in pounds... feet the speed of compressor may be increased 5 single strokes per minute for each 1,000 feet...

17. 49 CFR 230.71 - Orifice testing of compressors.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Compressor size Single strokes per minute Diameter of orifice(in inches) Air pressure maintained(in pounds... feet the speed of compressor may be increased 5 single strokes per minute for each 1,000 feet...

18. 49 CFR 230.71 - Orifice testing of compressors.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Compressor size Single strokes per minute Diameter of orifice(in inches) Air pressure maintained(in pounds... feet the speed of compressor may be increased 5 single strokes per minute for each 1,000 feet...

19. 49 CFR 230.71 - Orifice testing of compressors.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Compressor size Single strokes per minute Diameter of orifice(in inches) Air pressure maintained(in pounds... feet the speed of compressor may be increased 5 single strokes per minute for each 1,000 feet...

20. 49 CFR 230.71 - Orifice testing of compressors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Compressor size Single strokes per minute Diameter of orifice(in inches) Air pressure maintained(in pounds... feet the speed of compressor may be increased 5 single strokes per minute for each 1,000 feet...

1. Program sizes flange or pipe-tap orifice plates

SciTech Connect

Hogsett, J.E.

1984-03-12

A program has been developed for the HP-41CV programmable calculator that is designed to compute differential pressure across an orifice, gas flow through an orifice, or the orifice-plate bore for orifice plates with flange or pipe taps. It is designed to save time in extracting values from charts, tables, and graphs which are required to perform the calculations. It is based on equations and data from Spink. The program is run by inputing appropriate data via execution of a program entitled ''DATA IN,'' calculating differential pressure via program ''dH20,'' gas flow via program ''FLOW,'' and via program ''BORE.'' Flange-tap calculations are performed with FLAG 01 not set, while pipe-tap calculations are selected by setting FLAG 01.

2. Modeling of High-Energy Pulsed Laser Interactions with Coupons

SciTech Connect

Boley, C D; Rubenchik, A M

2003-02-06

We describe a computational model of laser-materials interactions in the regime accessed by the solid state heat capacity lasers (SSHCLs) built at LLNL. We show that its predictions compare quite favorably with coupon experiments by the 10 kW SSHCL at LLNL. The body of this paper describes the following topics, listed by section number: (2) model in quiescent air, (3) comparison with experiments in quiescent air, (4) effects of air flow, (5) comparison with experiments involving air flow, (6) importance of material properties, (7) advantage of pulsed lasers over CW lasers, and (8) conclusions and recommendations.

3. Fabrication of small-orifice fuel injectors for diesel engines.

SciTech Connect

Woodford, J. B.; Fenske, G. R.

2005-04-08

Diesel fuel injector nozzles with spray hole diameters of 50-75 {micro}m have been fabricated via electroless nickel plating of conventionally made nozzles. Thick layers of nickel are deposited onto the orifice interior surfaces, reducing the diameter from {approx}200 {micro}m to the target diameter. The nickel plate is hard, smooth, and adherent, and covers the orifice interior surfaces uniformly.

4. Apparatus for depositing hard coating in a nozzle orifice

DOEpatents

Flynn, P.L.; Giammarise, A.W.

1995-02-21

The present invention is directed to a process for coating the interior surfaces of an orifice in a substrate that forms a slurry fuel injection nozzle. In a specific embodiment, the nozzle is part of a fuel injection system for metering a coal-water slurry into a large, medium-speed, multi-cylinder diesel engine. In order to retard erosion of the orifice, the substrate is placed in a chemical vapor deposition (CVD) reaction chamber. A reaction gas is passed into the chamber at a gas temperature below its reaction temperature and is directed through the orifice in the substrate. The gas reaction temperature is a temperature at and above which the reaction gas deposits as a coating, and the reaction gas is of a composition whereby improved resistance to erosion by flow of the particulates in the slurry fuel is imparted by the deposited coating. Only the portion of the substrate in proximity to the orifice to be coated is selectively heated to at least the gas reaction temperature for effecting coating of the orifice`s interior surfaces by the vapor deposited coating formed from the reaction gas. 2 figs.

5. Traveling Pulses for a Two-Species Chemotaxis Model

PubMed Central

Emako, Casimir; Gayrard, Charlène; Buguin, Axel; Neves de Almeida, Luís; Vauchelet, Nicolas

2016-01-01

Mathematical models have been widely used to describe the collective movement of bacteria by chemotaxis. In particular, bacterial concentration waves traveling in a narrow channel have been experimentally observed and can be precisely described thanks to a mathematical model at the macroscopic scale. Such model was derived in [1] using a kinetic model based on an accurate description of the mesoscopic run-and-tumble process. We extend this approach to study the behavior of the interaction between two populations of E. Coli. Separately, each population travels with its own speed in the channel. When put together, a synchronization of the speed of the traveling pulses can be observed. We show that this synchronization depends on the fraction of the fast population. Our approach is based on mathematical analysis of a macroscopic model of partial differential equations. Numerical simulations in comparison with experimental observations show qualitative agreement. PMID:27071058

6. Numerically Modeling Pulsed-Current, Kinked Wire Experiments

Filbey, Gordon; Kingman, Pat

1999-06-01

The U.S. Army Research Laboratory (ARL) has embarked on a program to provide far-term land fighting vehicles with electromagnetic armor protection. Part of this work seeks to establish robust simulations of magneto-solid-mechanics phenomena. Whether describing violent rupture of a fuse link resulting from a large current pulse or the complete disruption of a copper shaped-charge jet subjected to high current densities, the simulations must include effects of intense Lorentz body forces and rapid Ohmic heating. Material models are required that describe plasticity, flow and fracture, conductivity, and equation of state (EOS) parameters for media in solid, liquid, and vapor phases. An extended version of the Eulerian wave code CTH has been used to predict the apex motion of a V-shaped (``kinked'') copper wire 3mm in diameter during a 400 kilo-amp pulse. These predictions, utilizing available material, EOS, and conductivity data for copper and the known characteristics of an existing capacitor-bank pulsed power supply, were then used to configure an experiment. The experiments were in excellent agreement with the prior simulations. Both computational and experimental results (including electrical data and flash X-rays) will be presented.

7. A neuron model of stochastic resonance using rectangular pulse trains.

PubMed

Danziger, Zachary; Grill, Warren M

2015-02-01

Stochastic resonance (SR) is the enhanced representation of a weak input signal by the addition of an optimal level of broadband noise to a nonlinear (threshold) system. Since its discovery in the 1980s the domain of input signals shown to be applicable to SR has greatly expanded, from strictly periodic inputs to now nearly any aperiodic forcing function. The perturbations (noise) used to generate SR have also expanded, from white noise to now colored noise or vibrational forcing. This study demonstrates that a new class of perturbations can achieve SR, namely, series of stochastically generated biphasic pulse trains. Using these pulse trains as 'noise' we show that a Hodgkin Huxley model neuron exhibits SR behavior when detecting weak input signals. This result is of particular interest to neuroscience because nearly all artificial neural stimulation is implemented with square current or voltage pulses rather than broadband noise, and this new method may facilitate the translation of the performance gains achievable through SR to neural prosthetics.

8. Phenomenological Model of Current Sheet Canting in Pulsed Electromagnetic Accelerators

NASA Technical Reports Server (NTRS)

Markusic, Thomas; Choueiri, E. Y.

2003-01-01

The phenomenon of current sheet canting in pulsed electromagnetic accelerators is the departure of the plasma sheet (that carries the current) from a plane that is perpendicular to the electrodes to one that is skewed, or tipped. Review of pulsed electromagnetic accelerator literature reveals that current sheet canting is a ubiquitous phenomenon - occurring in all of the standard accelerator geometries. Developing an understanding of current sheet canting is important because it can detract from the propellant sweeping capabilities of current sheets and, hence, negatively impact the overall efficiency of pulsed electromagnetic accelerators. In the present study, it is postulated that depletion of plasma near the anode, which results from axial density gradient induced diamagnetic drift, occurs during the early stages of the discharge, creating a density gradient normal to the anode, with a characteristic length on the order of the ion skin depth. Rapid penetration of the magnetic field through this region ensues, due to the Hall effect, leading to a canted current front ahead of the initial current conduction channel. In this model, once the current sheet reaches appreciable speeds, entrainment of stationary propellant replenishes plasma in the anode region, inhibiting further Hall-convective transport of the magnetic field; however, the previously established tilted current sheet remains at a fairly constant canting angle for the remainder of the discharge cycle, exerting a transverse J x B force which drives plasma toward the cathode and accumulates it there. This proposed sequence of events has been incorporated into a phenomenological model. The model predicts that canting can be reduced by using low atomic mass propellants with high propellant loading number density; the model results are shown to give qualitative agreement with experimentally measured canting angle mass dependence trends.

9. 2-D Magnetohydrodynamic Modeling of A Pulsed Plasma Thruster

NASA Technical Reports Server (NTRS)

Thio, Y. C. Francis; Cassibry, J. T.; Wu, S. T.; Rodgers, Stephen L. (Technical Monitor)

2002-01-01

Experiments are being performed on the NASA Marshall Space Flight Center (MSFC) MK-1 pulsed plasma thruster. Data produced from the experiments provide an opportunity to further understand the plasma dynamics in these thrusters via detailed computational modeling. The detailed and accurate understanding of the plasma dynamics in these devices holds the key towards extending their capabilities in a number of applications, including their applications as high power (greater than 1 MW) thrusters, and their use for producing high-velocity, uniform plasma jets for experimental purposes. For this study, the 2-D MHD modeling code, MACH2, is used to provide detailed interpretation of the experimental data. At the same time, a 0-D physics model of the plasma initial phase is developed to guide our 2-D modeling studies.

10. Orifice plate for controlling solids flow, methods of use thereof and articles comprising the same

DOEpatents

Jukkola, Glen D.; Teigen, Bard C.

2017-01-31

Disclosed herein is an orifice plate comprising one or more plates having orifices disposed therein; the orifices being operative to permit the flow of solids from a moving bed heat exchanger to a solids flow control system; where the orifice plate is downstream of a tube bundle of the moving bed heat exchanger and upstream of the solids flow control system and wherein the orifice plate is operative to evenly distribute the flow of solids in the solids flow control system.

11. System characterization of a novel haptic interface for natural orifice translumenal endoscopic surgery simulation.

PubMed

Dargar, Saurabh; Sankaranarayanan, Ganesh; De, Suvranu

2014-01-01

Natural orifice translumenal endoscopic surgery (NOTES) is a minimally invasive procedure, which utilizes the body's natural orifices to gain access to the peritoneal cavity. The VTEST(©) is a virtual reality NOTES simulator developed at the CeMSIM at RPI to train surgeons in NOTES. A novel 2 DOF decoupled haptic device was designed and built for this simulator. The haptic device can render 5.62 N and 190.05 N-mm of continuous force and torque respectively. In this work we have evaluated the haptic interface and developed a model to accurately describe the system behavior, to further incorporate into an impedance type controller for realistic haptic rendering in the VTEST(©).

12. Process for depositing hard coating in a nozzle orifice

DOEpatents

Flynn, Paul L.; Giammarise, Anthony W.

1991-01-01

The present invention is directed to a process for coating the interior surfaces of an orifice in a substrate that forms a slurry fuel injection nozzle. In a specific embodiment, the nozzle is part of a fuel injection system for metering a coal-water slurry into a large, medium-speed, multi-cylinder diesel engine. In order to retard erosion of the orifice, the substrate is placed in a chemical vapor deposition (CVD) reaction chamber. A reaction gas is passed into the chamber at a gas temperature below its reaction temperature and is directed through the orifice in the substrate. The gas reaction temperature is a temperature at and above which the reaction gas deposits as a coating, and the reaction gas is of a composition whereby improved resistance toerosion by flow of the particulates in the slurry fuel is imparted by the deposited coating. Only the portion of the substrate in proximity to the orifice to be coated is selectively heated to at least the gas reaction temperature for effecting coating of the orifice's interior surfaces by the vapor deposited coating formed from the reaction gas.

13. Process for depositing hard coating in a nozzle orifice

DOEpatents

Flynn, P.L.; Giammarise, A.W.

1991-10-29

The present invention is directed to a process for coating the interior surfaces of an orifice in a substrate that forms a slurry fuel injection nozzle. In a specific embodiment, the nozzle is part of a fuel injection system for metering a coal-water slurry into a large, medium-speed, multi-cylinder diesel engine. In order to retard erosion of the orifice, the substrate is placed in a chemical vapor deposition (CVD) reaction chamber. A reaction gas is passed into the chamber at a gas temperature below its reaction temperature and is directed through the orifice in the substrate. The gas reaction temperature is a temperature at and above which the reaction gas deposits as a coating, and the reaction gas is of a composition whereby improved resistance to erosion by flow of the particulates in the slurry fuel is imparted by the deposited coating. Only the portion of the substrate in proximity to the orifice to be coated is selectively heated to at least the gas reaction temperature for effecting coating of the orifice's interior surfaces by the vapor deposited coating formed from the reaction gas. 2 figures.

14. Apparatus for depositing hard coating in a nozzle orifice

DOEpatents

Flynn, Paul L.; Giammarise, Anthony W.

1995-01-01

The present invention is directed to a process for coating the interior surfaces of an orifice in a substrate that forms a slurry fuel injection nozzle. In a specific embodiment, the nozzle is part of a fuel injection system for metering a coal-water slurry into a large, medium-speed, multi-cylinder diesel engine. In order to retard erosion of the orifice, the substrate is placed in a chemical vapor deposition (CVD) reaction chamber. A reaction gas is passed into the chamber at a gas temperature below its reaction temperature and is directed through the orifice in the substrate. The gas reaction temperature is a temperature at and above which the reaction gas deposits as a coating, and the reaction gas is of a composition whereby improved resistance to erosion by flow of the particulates in the slurry fuel is imparted by the deposited coating. Only the portion of the substrate in proximity to the orifice to be coated is selectively heated to at least the gas reaction temperature for effecting coating of the orifice's interior surfaces by the vapor deposited coating formed from the reaction gas.

15. Gastrointestinal tract access for urological natural orifice transluminal endoscopic surgery

PubMed Central

Miakicheva, Olga; Hamilton, Zachary; Beksac, Alp T; Berquist, Sean W; Hassan, Abd-elrahman; Holden, Marc; Derweesh, Ithaar H

2016-01-01

We conducted a literature review of natural orifice transluminal endoscopic surgery (NOTES), focusing on urologic procedures with gastrointestinal tract access, to update on the development of this novel surgical approach. As part of the methods, a comprehensive electronic literature search for NOTES was conducted using PubMed and Cochrane Library from March 2002 to February 2016 for papers reporting urologic procedures performed utilizing gastrointestinal tract access. A total of 11 peer-reviewed studies examining utility of gastrointestinal access for NOTES urologic procedures were noted, with the first report in 2007. The procedures reported in the studies were total/radical nephrectomy, partial nephrectomy, adrenalectomy, and prostatectomy. The transgastric approach was identified in five studies examining total/radical nephrectomy (n = 2), partial nephrectomy (n = 1), partial cystectomy (n = 1), and adrenalectomy (n = 1). Six studies evaluated transrectal approach for NOTES, describing total/radical nephrectomy (n = 3), partial nephrectomy (n = 1), robotic nephrectomy with adrenalectomy (n = 1) and prostatectomy (n = 1). Feasibility was reported in all studies. Most studies were preclinical and acute, and limited by concerns regarding restricted instrumentation and infection risk. We concluded that gastrointestinal access for urologic NOTES demonstrates promise as described by outlined feasibility studies in preclinical models. Nonetheless, clinical application awaits further advancements in surgical technology and concerns regarding infectious potential. PMID:27909547

16. Numerical study of liquid-hydrogen droplet generation from a vibrating orifice

Xu, J.; Celik, D.; Hussaini, M. Y.; Van Sciver, S. W.

2005-08-01

Atomic hydrogen propellant feed systems for far-future spacecraft may utilize solid-hydrogen particle carriers for atomic species that undergo recombination to create hot rocket exhaust. Such technology will require the development of particle generation techniques. One such technique could involve the production of hydrogen droplets from a vibrating orifice that would then freeze in cryogenic helium vapor. Among other quantities, the shape and size of the droplet are of particular interest. The present paper addresses this problem within the framework of the incompressible Navier-Stokes equations for multiphase flows, in order to unravel the basic mechanisms of droplet formation with a view to control them. Surface tension, one of the most important mechanisms to determine droplet shape, is modeled as the source term in the momentum equation. Droplet shape is tracked using a volume-of-fluid approach. A dynamic meshing technique is employed to accommodate the vibration of the generator orifice. Numerically predicted droplet shapes show satisfactory agreement with photographs of droplets generated in experiments. A parametric study is carried out to understand the influence of injection velocity, nozzle vibrational frequency, and amplitude on the droplet shape and size. The computational model provides a definitive qualitative picture of the evolution of droplet shape as a function of the operating parameters. It is observed that, primarily, the orifice vibrational frequency affects the shape, the vibrational amplitude affects the time until droplet detachment from the orifice, and the injection velocity affects the size. However, it does not mean that, for example, there is no secondary effect of amplitude on shape or size.

17. Modelling of pulsed and steady-state DEMO scenarios

Giruzzi, G.; Artaud, J. F.; Baruzzo, M.; Bolzonella, T.; Fable, E.; Garzotti, L.; Ivanova-Stanik, I.; Kemp, R.; King, D. B.; Schneider, M.; Stankiewicz, R.; Stępniewski, W.; Vincenzi, P.; Ward, D.; Zagórski, R.

2015-07-01

Scenario modelling for the demonstration fusion reactor (DEMO) has been carried out using a variety of simulation codes. Two DEMO concepts have been analysed: a pulsed tokamak, characterized by rather conventional physics and technology assumptions (DEMO1) and a steady-state tokamak, with moderately advanced physics and technology assumptions (DEMO2). Sensitivity to impurity concentrations, radiation, and heat transport models has been investigated. For DEMO2, the impact of current driven non-inductively by neutral beams has been studied by full Monte Carlo simulations of the fast ion distribution. The results obtained are a part of a more extensive research and development (R&D) effort carried out in the EU in order to develop a viable option for a DEMO reactor, to be adopted after ITER for fusion energy research.

18. A new method for quantification of regurgitant flow rate using color Doppler flow imaging of the flow convergence region proximal to a discrete orifice. An in vitro study.

PubMed

Recusani, F; Bargiggia, G S; Yoganathan, A P; Raisaro, A; Valdes-Cruz, L M; Sung, H W; Bertucci, C; Gallati, M; Moises, V A; Simpson, I A

1991-02-01

While color Doppler flow mapping has yielded a quick and relatively sensitive method for visualizing the turbulent jets generated in valvular insufficiency, quantification of the degree of valvular insufficiency has been limited by the dependence of visualization of turbulent jets on hemodynamic as well as instrument-related factors. Color Doppler flow imaging, however, does have the capability of reliably showing the spatial relations of laminar flows. An area where flow accelerates proximal to a regurgitant orifice is commonly visualized on the left ventricular side of a mitral regurgitant orifice, especially when imaging is performed with high gain and a low pulse repetition frequency. This area of flow convergence, where the flow stream narrows symmetrically, can be quantified because velocity and the flow cross-sectional area change in inverse proportion along streamlines centered at the orifice. In this study, a gravity-driven constant-flow system with five sharp-edged diaphragm orifices (ranging from 2.9 to 12 mm in diameter) was imaged both parallel and perpendicular to the direction of flow through the orifice. Color Doppler flow images were produced by zero shifting so that the abrupt change in display color occurred at different velocities. This "aliasing boundary" with a known velocity and a measurable radial distance from the center of the orifice was used to determine an isovelocity hemisphere such that flow rate through the orifice was calculated as 2 pi r2 x Vr, where r is the radial distance from the center of the orifice to the color change and Vr is the velocity at which the color change was noted. Using Vr values from 54 to 14 cm/sec obtained with a 3.75-MHz transducer and from 75 to 18 cm/sec obtained with a 2.5-MHz transducer, we calculated flow rates and found them to correlate with measured flow rates (r = 0.94-0.99). The slope of the regression line was closest to unity when the lowest Vr and the correspondingly largest r were used in the

19. ARTICLES: Thermohydrodynamic models of the interaction of pulse-periodic radiation with matter

Arutyunyan, R. V.; Baranov, V. Yu; Bol'shov, Leonid A.; Malyuta, D. D.; Mezhevov, V. S.; Pis'mennyĭ, V. D.

1987-02-01

Experimental and theoretical investigations were made of the processes of drilling and deep melting of metals by pulsed and pulse-periodic laser radiation. Direct photography of the surface revealed molten metal splashing due to interaction with single CO2 laser pulses. A proposed thermohydrodynamic model was used to account for the experimental results and to calculate the optimal parameters of pulse-periodic radiation needed for deep melting. The melt splashing processes were simulated numerically.

20. Update on PHELIX Pulsed-Power Hydrodynamics Experiments and Modeling

Rousculp, Christopher; Reass, William; Oro, David; Griego, Jeffery; Turchi, Peter; Reinovsky, Robert; Devolder, Barbara

2013-10-01

The PHELIX pulsed-power driver is a 300 kJ, portable, transformer-coupled, capacitor bank capable of delivering 3-5 MA, 10 μs pulse into a low inductance load. Here we describe further testing and hydrodynamics experiments. First, a 4 nH static inductive load has been constructed. This allows for repetitive high-voltage, high-current testing of the system. Results are used in the calibration of simple circuit models and numerical simulations across a range of bank charges (+/-20 < V0 < +/-40 kV). Furthermore, a dynamic liner-on-target load experiment has been conducted to explore the shock-launched transport of particulates (diam. ~ 1 μm) from a surface. The trajectories of the particulates are diagnosed with radiography. Results are compared to 2D hydro-code simulations. Finally, initial studies are underway to assess the feasibility of using the PHELIX driver as an electromagnetic launcher for planer shock-physics experiments. Work supported by United States-DOE under contract DE-AC52-06NA25396.

1. Wave-packet model for excitation by ultrashort pulses

Suominen, Kalle-Antti; Garraway, Barry M.; Stenholm, Stig

1992-03-01

In this paper we discuss the excitation of a localized molecular ground-state wave function by a short laser pulse. With a one-dimensional approach we show when it is possible to excite a considerable fraction of the ground state without too much distortion of the shape of the wave packet. This is of interest in time-resolved molecular experiments where an excited wave packet is often taken as the initial state. We solve the two coupled wave equations numerically and compare results to an analytical approximation based on the Rosen-Zener model. The validity of the approximation and its breakdown is considered in detail. Special attention is paid to the effect of lengthening the pulse duration and the consequences of the accompanying number of Rabi flops occurring in the area theorem. When the approximation breaks down, the wave packet becomes distorted and spread out, but there are still interesting coherence effects due to the interplay between the Rabi flopping and the molecular dynamics; these are displayed and discussed. Finally, the relationship to other works and possible generalizations are presented.

2. Effect of nonsymmetrical flow resistance upon orifice impedance resistance

NASA Technical Reports Server (NTRS)

Posey, J. W.; Compton, K. J.

1974-01-01

A nonreactive orifice in an infinite baffle is analyzed. The pressure difference delta across the orifice varies sinusoidally with amplitude 1.0 and average value -P. The orifice resistance, delta p is discontinuous at zero velocity and exhibits the constant values R sub + and R sub - for u 0 and u 0, respectively. The resultant velocity has power in all harmonics of the excitation frequency. A quasi-linear resistance is defined and found to be relatively insensitive to the presence or absence of a resonant backing cavity; however, it does vary from 1.33 R sub + to 0.67 R sub + for a resistance ratio R sub +/R sub - between 0.5 and 2.0.

3. Effect of nozzle orifice geometry on spray, combustion, and emission characteristics under diesel engine conditions.

SciTech Connect

Som, S.; Longman, D. E; Ramirez, A. I.; Aggarwal, S. K.

2011-03-01

Diesel engine performance and emissions are strongly coupled with fuel atomization and spray processes, which in turn are strongly influenced by injector flow dynamics. Modern engines employ micro-orifices with different orifice designs. It is critical to characterize the effects of various designs on engine performance and emissions. In this study, a recently developed primary breakup model (KH-ACT), which accounts for the effects of cavitation and turbulence generated inside the injector nozzle is incorporated into a CFD software CONVERGE for comprehensive engine simulations. The effects of orifice geometry on inner nozzle flow, spray, and combustion processes are examined by coupling the injector flow and spray simulations. Results indicate that conicity and hydrogrinding reduce cavitation and turbulence inside the nozzle orifice, which slows down primary breakup, increasing spray penetration, and reducing dispersion. Consequently, with conical and hydroground nozzles, the vaporization rate and fuel air mixing are reduced, and ignition occurs further downstream. The flame lift-off lengths are the highest and lowest for the hydroground and conical nozzles, respectively. This can be related to the rate of fuel injection, which is higher for the hydroground nozzle, leading to richer mixtures and lower flame base speeds. A modified flame index is employed to resolve the flame structure, which indicates a dual combustion mode. For the conical nozzle, the relative role of rich premixed combustion is enhanced and that of diffusion combustion reduced compared to the other two nozzles. In contrast, for the hydroground nozzle, the role of rich premixed combustion is reduced and that of non-premixed combustion is enhanced. Consequently, the amount of soot produced is the highest for the conical nozzle, while the amount of NOx produced is the highest for the hydroground nozzle, indicating the classical tradeoff between them.

4. Modeling pulsed-laser melting of embedded semiconductor nanoparticles

SciTech Connect

Sawyer, C.A.; Guzman, J.; Boswell-Koller, C.N.; Sherburne, M.P.; Mastandrea, J.P.; Bustillo, K.C.; Ager III, J.W.; Haller, E.E.; Chrzan, D.C.

2011-05-18

Pulsed-laser melting (PLM) is commonly used to achieve a fast quench rate in both thin films and nanoparticles. A model for the size evolution during PLM of nanoparticles confined in a transparent matrix, such as those created by ion-beam synthesis, is presented. A self-consistent mean-field rate equations approach that has been used successfully to model ion beam synthesis of germanium nanoparticles in silica is extended to include the PLM process. The PLM model includes classical optical absorption, multiscale heat transport by both analytical and finite difference methods, and melting kinetics for confined nanoparticles. The treatment of nucleation and coarsening behavior developed for the ion beam synthesis model is modified to allow for a non-uniform temperature gradient and for interacting liquid and solid particles with different properties. The model allows prediction of the particle size distribution after PLM under various laser fluences, starting from any particle size distribution including as-implanted or annealed simulated samples. A route for narrowing the size distribution of embedded nanoparticles is suggested, with simulated distribution widths as low as 15% of the average size.

5. Modeling pulsed-laser melting of embedded semiconductor nanoparticles

Sawyer, C. A.; Guzman, J.; Boswell-Koller, C. N.; Sherburne, M. P.; Mastandrea, J. P.; Bustillo, K. C.; Ager, J. W.; Haller, E. E.; Chrzan, D. C.

2011-11-01

Pulsed-laser melting (PLM) is commonly used to achieve a fast quench rate in both thin films and nanoparticles. A model for the size evolution during PLM of nanoparticles confined in a transparent matrix, such as those created by ion-beam synthesis, is presented. A self-consistent mean-field rate equations approach that has been used successfully to model ion beam synthesis of germanium nanoparticles in silica is extended to include the PLM process. The PLM model includes classical optical absorption, multiscale heat transport by both analytical and finite difference methods, and melting kinetics for confined nanoparticles. The treatment of nucleation and coarsening behavior developed for the ion beam synthesis model is modified to allow for a nonuniform temperature gradient and for interacting liquid and solid particles with different properties. The model allows prediction of the particle size distribution after PLM under various laser fluences, starting from any particle size distribution including as-implanted or annealed simulated samples. A route for narrowing the size distribution of embedded nanoparticles is suggested, with simulated distribution widths as low as 15% of the average size.

6. Performance Evaluation of Steam Traps and Orifice Plates.

DTIC Science & Technology

1980-10-01

ADlAO9dl 229 JOHNS - MANVILLE SALES CORP DENVER CO RESEARCH AND DEV-’ETC F/S 13/1 PERFOR1ANCE EVALUATION OF STEAM TRAPS AND ORIFICE PLATES.(U)/ OCT 80...AGENCY t REPORT FESA-TS-2085 41! PERFORMANCE EVALUATION OF STEAM TRAPS AND ORIFICE PLATES P. B. SHEPHERD JOHNS - MANVILLE SALES CORPORATION w RESEARCH...PERFORMING ORGANIZATION NAME ANED ADDPESS!_ i lFioC’iA.TCr ’.ETPlJ A~ Johns - Manville Sales Corporation &00* 0 - Research & Development Center qOll Ken

7. Acoustic response of a rectangular levitator with orifices

NASA Technical Reports Server (NTRS)

El-Raheb, Michael; Wagner, Paul

1990-01-01

The acoustic response of a rectangular cavity to speaker-generated excitation through waveguides terminating at orifices in the cavity walls is analyzed. To find the effects of orifices, acoustic pressure is expressed by eigenfunctions satisfying Neumann boundary conditions as well as by those satisfying Dirichlet ones. Some of the excess unknowns can be eliminated by point constraints set over the boundary, by appeal to Lagrange undetermined multipliers. The resulting transfer matrix must be further reduced by partial condensation to the order of a matrix describing unmixed boundary conditions. If the cavity is subjected to an axial temperature dependence, the transfer matrix is determined numerically.

8. Modeling boron profiles in silicon after pulsed excimer laser annealing

SciTech Connect

Hackenberg, M.; Huet, K.; Negru, R.; Venturini, J.; Fisicaro, G.; La Magna, A.; Pichler, P.

2012-11-06

In this work, we investigated four possible mechanisms which were candidates to explain the shape of boron profiles after ion implantation and melting excimer laser annealing in silicon. A laser with a wavelength of 308 nm and a pulse duration of {approx}180 ns was used. To simulate this process, an existing model for the temperature and phase evolution was complemented with equations for the migration of dopants. Outdiffusion, thermodiffusion, segregation, and adsorption were investigated as possible mechanisms. As a result, we found that outdiffusion and segregation can be excluded as major mechanisms. Thermodiffusion as well as adsorption could both reproduce the build-up at low melt depths, but only adsorption the one at deeper melt depths. In both cases, ion beam mixing during SIMS measurement had to be taken into account to reproduce the measured profiles.

9. Evidence of thermal additivity during short laser pulses in an in vitro retinal model

Denton, Michael L.; Tijerina, Amanda J.; Dyer, Phillip N.; Oian, Chad A.; Noojin, Gary D.; Rickman, John M.; Shingledecker, Aurora D.; Clark, Clifton D.; Castellanos, Cherry C.; Thomas, Robert J.; Rockwell, Benjamin A.

2015-03-01

Laser damage thresholds were determined for exposure to 2.5-ms 532-nm pulses in an established in vitro retinal model. Single and multiple pulses (10, 100, 1000) were delivered to the cultured cells at three different pulse repetition frequency (PRF) values, and overt damage (membrane breach) was scored 1 hr post laser exposure. Trends in the damage data within and across the PRF range identified significant thermal additivity as PRF was increased, as evidenced by drastically reduced threshold values (< 40% of single-pulse value). Microthermography data that were collected in real time during each exposure also provided evidence of thermal additivity between successive laser pulses. Using thermal profiles simulated at high temporal resolution, damage threshold values were predicted by an in-house computational model. Our simulated ED50 value for a single 2.5-ms pulse was in very good agreement with experimental results, but ED50 predictions for multiple-pulse trains will require more refinement.

10. Conductivity depth imaging of Airborne Electromagnetic data with double pulse transmitting current based on model fusion

Li, Jing; Dou, Mei; Lu, Yiming; Peng, Cong; Yu, Zining; Zhu, Kaiguang

2017-01-01

The airborne electromagnetic (AEM) systems have been used traditionally in mineral exploration. Typically the system transmits a single pulse waveform to detect conductive anomaly. Conductivity-depth imaging (CDI) of data is generally applied in identifying conductive targets. A CDI algorithm with double-pulse transmitting current based on model fusion is developed. The double-pulse is made up of a half-sine pulse of high power and a trapezoid pulse of low power. This CDI algorithm presents more shallow information than traditional CDI with a single pulse. The electromagnetic response with double-pulse transmitting current is calculated by linear convolution based on forward modeling. The CDI results with half-sine and trapezoid pulse are obtained by look-up table method, and the two results are fused to form a double-pulse conductivity-depth imaging result. This makes it possible to obtain accurate conductivity and depth. Tests on synthetic data demonstrate that CDI algorithm with double-pulse transmitting current based on model fusion maps a wider range of conductivities and does a better job compared with CDI with a single pulse transmitting current in reflecting the whole geological conductivity changes.

11. [A mathematical model of hemodynamic processes for distal pulse wave formation].

PubMed

Fedotov, A A

2015-01-01

A mathematical model of the formation of distal arterial pulse wave signal in the blood vessels of the upper limbs was considered. The formation of distal arterial pulse wave is represented as a composition of forward and reverse pulse waves propagating along the human arterial system. The system of formal analogy between pulse waves propagation along the human arterial system and the propagation of electrical oscillations in electrical transmission lines with distributed parameters was proposed. Dependencies of pulse wave propagation along the human arterial system were obtained by solving the one-dimensional Navier-Stokes equations for a few special cases.

12. Modeling digital pulse waveforms by solving one-dimensional Navier-stokes equations.

PubMed

Fedotov, Aleksandr A; Akulova, Anna S; Akulov, Sergey A

2016-08-01

Mathematical modeling for composition distal arterial pulse wave in the blood vessels of the upper limbs was considered. Formation of distal arterial pulse wave is represented as a composition of forward and reflected pulse waves propagating along the arterial vessels. The formal analogy between pulse waves propagation along the human arterial system and the propagation of electrical oscillations in electrical transmission lines with distributed parameters was proposed. Dependencies of pulse wave propagation along the human arterial system were obtained by solving the one-dimensional Navier-Stokes equations for a few special cases.

13. Numerical Modeling of Pulse Detonation Rocket Engine Gasdynamics And Performance

NASA Technical Reports Server (NTRS)

Morris, Christopher I.

2004-01-01

Pulse detonation rocket engines (PDREs) offer potential performance improvements over conventional designs, but represent a challenging modeling task. A quasi-1-D, finite-rate chemistry computational fluid dynamics model for PDREs is described and implemented. Four different PDRE geometries are evaluated in this work: a baseline detonation tube, a detonation tube with a straight extension, and a detonation tube with two types of converging-diverging (C-D) nozzles. The effect of extension length and C-D nozzle area ratio on the single-shot gasdynamics and performance of a PDRE is studied over a wide range of blowdown pressure ratios (1-1000). The results indicate that a C-D nozzle is generally more effective than a straight extension in improving PDRE performance, particularly at higher pressure ratios. Additionally, the results show that the blowdown process of the C-D nozzle systems could be beneficially cut off well before the pressure at the end-wall reaches the ambient value. The performance results are also compared to a steady-state rocket system using similar modeling assumptions.

14. Experimental Investigation of Cavitation Induced Feedline Instability from an Orifice

NASA Technical Reports Server (NTRS)

Hitt, Matthew A.; Lineberry, David M.; Ahuja, Vineet; Frederick, Robert A,

2012-01-01

This paper details the results of an experimental investigation into the cavitation instabilities created by a circular orifice conducted at the University of Alabama in Huntsville Propulsion Research Center. This experiment was conducted in concert with a computational simulation to serve as a reference point for the simulation. Testing was conducted using liquid nitrogen as a cryogenic propellant simulant. A 1.06 cm diameter thin orifice with a rounded inlet was tested in an approximately 1.25 kg/s flow with inlet pressures ranging from 504.1 kPa to 829.3 kPa. Pressure fluctuations generated by the orifice were measured using a high frequency pressure sensor located 0.64 tube diameters downstream of the orifice. Fast Fourier Transforms were performed on the high frequency data to determine the instability frequency. Shedding resulted in a primary frequency with a cavitation related subharmonic frequency. For this experiment, the cavitation instability ranged from 153 Hz to 275 Hz. Additionally, the strength of the cavitation occur red as a function of cavitation number. At lower cavitation numbers, the strength of the cavitation instability ranged from 2.4 % to 7 % of the inlet pressure. However, at higher cavitation numbers, the strength of the cavitation instability ranged from 0.6 % to 1 % of the inlet pressure.

15. In-flight investigation of shuttle tile pressure orifice installations

NASA Technical Reports Server (NTRS)

Moes, Timothy R.; Meyer, Robert R., Jr.

1990-01-01

To determine shuttle orbiter wing loads during ascent, wing load instrumentation was added to Columbia (OV-102). This instrumentation included strain gages and pressure orifices on the wing. The loads derived from wing pressure measurements taken during STS 61-C did not agree with those derived from strain gage measurements or with the loads predicted from the aerodynamic database. Anomalies in the surface immediately surrounding the pressure orifices in the thermal protection system (TPS) tiles were one possible cause of errors in the loads derived from wing pressure measurements. These surface anomalies were caused by a ceramic filler material which was installed around the pressure tubing. The filler material allowed slight movement of the TPS tile and pressure tube as the airframe flexed and bent under aerodynamic loads during ascent and descent. Postflight inspection revealed that this filler material had protruded from or receeded beneath the surface, causing the orifice to lose its flushness. Flight tests were conducted at NASA Ames Research Center Dryden Flight Research Facility to determine the effects of any anomaly in surface flushness of the orifice installation on the measured pressures at Mach numbers between 0.6 and 1.4. An F-104 aircraft with a flight test fixture mounted beneath the fuselage was used for these flights. Surface flushness anomalies typical of those on the orbiter after flight (STA 61-C) were tested. Also, cases with excessive protrusion and recession of the filler material were tested. This report shows that the anomalies in STS 61-C orifice installations adversely affected the pressure measurements. But the magnitude of the affect was not great enough to account for the discrepancies with the strain gage measurements and the aerodynamic predictions.

16. A Pulse-Type Hardware CPG Model for Generation and Transition of Quadruped Locomotion Pattern

Hata, Keiko; Sekine, Yoshifumi; Nakabora, Yoshifumi; Saeki, Katsutoshi

The purpose of our research is to clarify information processing functions of living organisms by neural networks using pulse-type hardware neuron models and applying pulse-type hardware neural networks to engineered models. It is known that locomotion such as walking by a living organism is generated and transited by CPG (Central Pattern Generator) in the central nervous system. We investigate a pulse-type hardware CPG model using coupled oscillator composed of pulse-type hardware neuron models. A CPG model is need to generate and control quadruped locomotion. In this paper, we describe generation and transition of oscillation patterns, corresponding to quadruped locomotion patterns. As a result, it is shown that generation and transition of oscillation patterns are possible by giving external inputs of one pulse to the CPG model.

17. Experimental verification of physical model of pulsed laser welding

SciTech Connect

Jellison, J.L.; Keicher, D.M.

1990-01-01

Whereas most experimental and theoretical studies of the role of convection in fusion welding have been concerned with continuous heat sources, a pulsed heat source is the focus of this study. This is primarily an experimental study of the pulsed Nd:YAG laser welding of austenitic stainless steels. 12 refs., 9 figs.

18. Modeling of High Efficiency Solar Cells Under Laser Pulse for Power Beaming Applications

NASA Technical Reports Server (NTRS)

Jain, Raj K.; Landis, Geoffrey A.

1994-01-01

Solar cells may be used as receivers for laser power beaming. To understand the behavior of solar cells when illuminated by a pulsed laser, the time response of gallium arsenide and silicon solar cells to pulsed monochromatic input has been modeled using a finite element solar cell model.

19. Investigation of the Acoustic Source Characteristics of High Energy Laser Pulses: Models and Experiment

DTIC Science & Technology

2008-06-01

consistent with the expected approximately 1/r relationship for pressure amplitudes under 100MPa. The modeling effort employed AUTODYN , a finite...agreed with Vogel’s measured values. The efficiency, pulse length, pulse shape, and variation of pressure amplitude with range achieved with AUTODYN ...Nonlinear Acoustics, AUTODYN , Acoustic Modeling, Shock Acoustics 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY

20. Individualization of the parameters of the three-elements Windkessel model using carotid pulse signal

Żyliński, Marek; Niewiadomski, Wiktor; Strasz, Anna; GÄ siorowska, Anna; Berka, Martin; Młyńczak, Marcel; Cybulski, Gerard

2015-09-01

The haemodynamics of the arterial system can be described by the three-elements Windkessel model. As it is a lumped model, it does not account for pulse wave propagation phenomena: pulse wave velocity, reflection, and pulse pressure profile changes during propagation. The Modelflowmethod uses this model to calculate stroke volume and total peripheral resistance (TPR) from pulse pressure obtained from finger; the reliability of this method is questioned. The model parameters are: aortic input impedance (Zo), TPR, and arterial compliance (Cw). They were obtained from studies of human aorta preparation. Individual adjustment is performed based on the subject's age and gender. As Cw is also affected by diseases, this may lead to inaccuracies. Moreover, the Modelflowmethod transforms the pulse pressure recording from the finger (Finapres©) into a remarkably different pulse pressure in the aorta using a predetermined transfer function — another source of error. In the present study, we indicate a way to include in the Windkessel model information obtained by adding carotid pulse recording to the finger pressure measurement. This information allows individualization of the values of Cw and Zo. It also seems reasonable to utilize carotid pulse, which better reflects aortic pressure, to individualize the transfer function. Despite its simplicity, the Windkessel model describes essential phenomena in the arterial system remarkably well; therefore, it seems worthwhile to check whether individualization of its parameters would increase the reliability of results obtained with this model.

1. Measuring Neutron Star Radii via Pulse Profile Modeling with NICER

Özel, Feryal; Psaltis, Dimitrios; Arzoumanian, Zaven; Morsink, Sharon; Bauböck, Michi

2016-11-01

The Neutron-star Interior Composition Explorer is an X-ray astrophysics payload that will be placed on the International Space Station. Its primary science goal is to measure with high accuracy the pulse profiles that arise from the non-uniform thermal surface emission of rotation-powered pulsars. Modeling general relativistic effects on the profiles will lead to measuring the radii of these neutron stars and to constraining their equation of state. Achieving this goal will depend, among other things, on accurate knowledge of the source, sky, and instrument backgrounds. We use here simple analytic estimates to quantify the level at which these backgrounds need to be known in order for the upcoming measurements to provide significant constraints on the properties of neutron stars. We show that, even in the minimal-information scenario, knowledge of the background at a few percent level for a background-to-source countrate ratio of 0.2 allows for a measurement of the neutron star compactness to better than 10% uncertainty for most of the parameter space. These constraints improve further when more realistic assumptions are made about the neutron star emission and spin, and when additional information about the source itself, such as its mass or distance, are incorporated.

2. A model of preliminary breakdown pulse peak currents and their relation to the observed electric field pulses

Kašpar, Petr; Santolík, Ondřej; Kolmašová, Ivana; Farges, Thomas

2017-01-01

Preliminary breakdown pulses (PBPs) occur in the initial phase of lightning. A realistic model for their description is employed to investigate relation between PBP peak currents and PBP electric field amplitudes and their relation to the return stroke (RS) peak currents. We demonstrate that the PBP peak currents can reach 200 kA and can be comparable or higher than the corresponding RS peak currents. For a typical PBP electric field waveform PBP peak currents are approximately proportional to the electric field amplitudes. We show that the PBP bipolar overshoot depends primarily on the characteristic time of the line conductivity increase. The magnitude of the charge centers is demonstrated to be very large in order to model the observed PBPs with amplitudes up to 32 V/m at 100 km. Such energetic current pulses might be capable to produce elves or terrestrial gamma ray flashes.

3. Update on Phelix Pulsed-Power Hydrodynamics Experiments and Modeling

DTIC Science & Technology

2013-06-01

toroidal transformer where their inner conductor forms the primary winding. The whole system resides on a transportable palette that is enclosed within...an EMI shielding box. Figure 1. Schematic of the PHELIX portable pulsed- power system. II. TOROIDAL TRANSFORMER The key technology to...achieving high-current pulses with a small footprint is a toroidal current step-up transformer. The toroidal geometry confines magnetic flux self

4. Acoustic impedance measurements of pulse tube refrigerators

Iwase, Takashi; Biwa, Tetsushi; Yazaki, Taichi

2010-02-01

Complex acoustic impedance is determined in a prototype refrigerator that can mimic orifice-type, inertance-type, and double inlet-type pulse tube refrigerators from simultaneous measurements of pressure and velocity oscillations at the cold end. The impedance measurements revealed the means by which the oscillatory flow condition in the basic pulse tube refrigerator is improved by additional components such as a valve and a tank. The working mechanism of pulse tube refrigerators is explained based on an electrical circuit analogy.

5. Experimental Visualization of Bubble Formation from an Orifice In Microgravity in the Presence of Electric Fields

NASA Technical Reports Server (NTRS)

Herman, C.; Iacona, E.; Foldes, I. B.; Suner, G.; Milburn, C.

2002-01-01

The formation of air bubbles injected into a stagnant, isothermal liquid in microgravity through an orifice was studied. The bubbles grew very large in microgravity. They attained a nearly spherical shape and showed pronounced affinity towards coalescence in the absence of electric fields and other perturbations. Under the influence of electric fields, periodic detachment was observed, with bubble sizes larger than in terrestrial conditions. The bubble shape was elongated. After detachment, the bubbles moved away from the electrode at which they formed without coalescing with other bubbles. Experimental data on bubble shape and size at detachment showed good agreement with models.

6. Thermomolecular effect on pressure measurements with orifices in transitional flow

NASA Technical Reports Server (NTRS)

Potter, J. L.; Blanchard, Robert C.

1991-01-01

Results are presented of a study carried out in order to verify a version of the method (presented at the 7th International Rarefied Gas Dynamics Symposium) for calculating the influence of thermomolecular flow on the pressures measured by means of orifices in walls exposed to rarefied gases. In these experiments, the 'orifice effect' is examined under conditions that are significantly different from those for which the semiempirical (SE) method of Kinslow and Potter (1971) was shown to be successful. Comparisons between the predicted results with flight data and the results obtained in the laboratory, combined with limited DSMC calculations, indicate that the SE method remains a useful tool which is relatively easy to apply and which gives good results when an appropriate energy accommodation coefficient is used.

7. Vortex structures in turbulent channel flow behind an orifice

Makino, Soichiro; Iwamoto, Kaoru; Kawamura, Hiroshi

2006-11-01

Direct numerical simulation of a channel flow with an orifice has been performed for Reτ0=10 - 600, where uτ0 is the friction velocity calculated from the mean pressure gradient, δ the channel half width and ν the kinematic viscosity. In the wake region, the mean flow becomes asymmetric by the Coanda effect. The degree of asymmetry increases with increasing the Reynolds number for the laminar flow at Reτ0< 50. The degree decreases abruptly at Reτ0=50, where the transition from the laminar to the turbulent flow take places. Large-scale spanwise vortices generated at the orifice edges. They become deformed and break up into disordered small-scale structures in shear layer. The small-scale vortices are convected towards the channel center. The large-scale vortices have an important effect upon the reattachment locations and streamwise vortices near the wall in the wake region.

8. Studies of flows through N-sequential orifices

NASA Technical Reports Server (NTRS)

Hendricks, R. C.; Stetz, T. T.

1983-01-01

Critical mass flux and axial pressure profile data for fluid nitrogen are presented for N = 20, 15, 10, and 7 N-sequential-orifice-inlet configurations uniformly spaced at 15.5 cm. These data correlate well over a wide range in reduced temperature and reduced pressure, and are in general agreement with previous studies of one to four inlets. Experimental and theoretical agreement is good for liquid and gas critical mass flux, but inconclusive in the near thermodynamic critical regions.

9. Bessel-Gauss pulse as an appropriate mathematical model for optically realizable localized waves.

PubMed

Reivelt, Kaido; Saari, Peeter

2004-06-01

We show that the field of the optically feasible luminal localized wave solutions of the scalar homogeneous wave equation can be modeled by means of Bessel-Gauss pulses. As the Bessel-Gauss pulses have a closed-form expression, this fact may be of great value in numerical simulations of various experimental situations.

10. LANL Efforts on Neutron Coincidence Modeling of INL Pulsed Neutron Data

SciTech Connect

Stewart, Scott; Thron, Jonathan L.; Swinhoe, Martyn T.; Geist, William H.; Charlton, William S.

2012-06-25

Overview of this presentation is: (1) pulsed histogram analysis, (2) creation of SPNS, (3) use of SPNS for modeling pulsed neutron data, (4) creation of MUDI, (5) calculated accidentals correction using GUAM + MUDI, (6) background subtraction analysis, and (7) current/figure work with MCNP.

11. Sonic injection through diamond orifices into a hypersonic flow

Fan, Huaiguo

The objective for the present study was to experimentally characterize the performance of diamond shaped injectors for hypersonic flow applications. First, an extensive literature review was performed. Second, a small scale Mach 5.0 wind tunnel facility was installed. Third, a detailed experimental parametric investigation of sonic injection through a diamond orifice (five incidence angles and three momentum ratios) and a circular injector (three momentum ratios) into the Mach 5.0 freestream was performed. Also, the use of downstream plume vorticity control ramps was investigated. Fourth, a detailed analysis of the experimental data to characterize and model the flow for the present range of conditions was achieved. The experimental techniques include surface oil flow visualization, Mie-Scattering flow visualization, particle image velocimetry (PIV), shadowgraph photograph, and a five-hole mean flow probe. The results show that the diamond injectors have the potential to produce attached shock depending on the incidence angle and jet momentum ratio. For example, the incidence angles less than or equal to 45° at J = 0.43 generated attached interaction shocks. The attached shock produced reduced total pressure loss (drag for scramjet) and eliminated potential hot spots, associated with the upstream flow separation. The jet interaction shock angle increased with jet incidence angle and momentum ratio due to increased penetration and flow disturbances. The plume penetration and cross-sectional area increased with incidence angle and momentum ratio. The increased jet interaction shock angle and strength produced increased total pressure loss, jet interaction force and total normal force. The characteristic kidney bean shaped plume was not discernable from the diamond injectors indicating increased effectiveness for film cooling applications. A vorticity generation ramp increased the penetration of the plume and the plume shape was indicative of higher levels of

12. Stochastic analysis of a pulse-type prey-predator model

Wu, Y.; Zhu, W. Q.

2008-04-01

A stochastic Lotka-Volterra model, a so-called pulse-type model, for the interaction between two species and their random natural environment is investigated. The effect of a random environment is modeled as random pulse trains in the birth rate of the prey and the death rate of the predator. The generalized cell mapping method is applied to calculate the probability distributions of the species populations at a state of statistical quasistationarity. The time evolution of the population densities is studied, and the probability of the near extinction time, from an initial state to a critical state, is obtained. The effects on the ecosystem behaviors of the prey self-competition term and of the pulse mean arrival rate are also discussed. Our results indicate that the proposed pulse-type model shows obviously distinguishable characteristics from a Gaussian-type model, and may confer a significant advantage for modeling the prey-predator system under discrete environmental fluctuations.

13. Stochastic analysis of a pulse-type prey-predator model.

PubMed

Wu, Y; Zhu, W Q

2008-04-01

A stochastic Lotka-Volterra model, a so-called pulse-type model, for the interaction between two species and their random natural environment is investigated. The effect of a random environment is modeled as random pulse trains in the birth rate of the prey and the death rate of the predator. The generalized cell mapping method is applied to calculate the probability distributions of the species populations at a state of statistical quasistationarity. The time evolution of the population densities is studied, and the probability of the near extinction time, from an initial state to a critical state, is obtained. The effects on the ecosystem behaviors of the prey self-competition term and of the pulse mean arrival rate are also discussed. Our results indicate that the proposed pulse-type model shows obviously distinguishable characteristics from a Gaussian-type model, and may confer a significant advantage for modeling the prey-predator system under discrete environmental fluctuations.

14. Accurate modeling of high-repetition rate ultrashort pulse amplification in optical fibers

PubMed Central

Lindberg, Robert; Zeil, Peter; Malmström, Mikael; Laurell, Fredrik; Pasiskevicius, Valdas

2016-01-01

A numerical model for amplification of ultrashort pulses with high repetition rates in fiber amplifiers is presented. The pulse propagation is modeled by jointly solving the steady-state rate equations and the generalized nonlinear Schrödinger equation, which allows accurate treatment of nonlinear and dispersive effects whilst considering arbitrary spatial and spectral gain dependencies. Comparison of data acquired by using the developed model and experimental results prove to be in good agreement. PMID:27713496

15. Modeling the Pulse Signal by Wave-Shape Function and Analyzing by Synchrosqueezing Transform

PubMed Central

Wang, Chun-Li; Yang, Yueh-Lung; Wu, Wen-Hsiang; Tsai, Tung-Hu; Chang, Hen-Hong

2016-01-01

We apply the recently developed adaptive non-harmonic model based on the wave-shape function, as well as the time-frequency analysis tool called synchrosqueezing transform (SST) to model and analyze oscillatory physiological signals. To demonstrate how the model and algorithm work, we apply them to study the pulse wave signal. By extracting features called the spectral pulse signature, and based on functional regression, we characterize the hemodynamics from the radial pulse wave signals recorded by the sphygmomanometer. Analysis results suggest the potential of the proposed signal processing approach to extract health-related hemodynamics features. PMID:27304979

16. Understanding variation in ecosystem pulse responses to wetting: Benefits of data-model coupling

Jenerette, D.

2011-12-01

Metabolic pulses of activity are a common ecological response to intermittently available resources and in water-limited ecosystems these pulses often occur in response to wetting. Net ecosystem CO2 exchange (NEE) in response to episodic wetting events is hypothesized to have a complex trajectory reflecting the distinct responses, or "pulses", of respiration and photosynthesis. To help direct research activities a physiological-based model of whole ecosystem metabolic activity up- and down-regulation was developed to investigate ecosystem energy balance and gas exchange pulse responses following precipitation events. This model was to investigate pulse dynamics from a local network of sites in southern Arizona, a global network of eddy-covariance ecosystem monitoring sites, laboratory incubation studies, and field manipulations. Pulse responses were found to be ubiquitous across ecosystem types. These pulses had a highly variable influence on NEE following wetting, ranging from large net sinks to sources of CO2 to the atmosphere. Much of the variability in pulse responses of NEE could be described through a coupled up- and down-regulation pulse response model. Respiration pulses were hypothesized to occur through a reduction in whole ecosystem activation energy; this model was both useful and corroborated through laboratory incubation studies of soil respiration. Using the Fluxnet eddy-covariance measurement database event specific responses were combined with the pulse model into an event specific twenty-five day net flux calculation. Across all events observed a general net accumulation of CO2 following a precipitation event, with the largest net uptake within deciduous broadleaf forests and smallest within grasslands. NEE pulses favored greater uptake when pre-event ecosystem respiration rates and total precipitation were higher. While the latter was expected, the former adds to previous theory by suggesting a larger net uptake of CO2 when pre-event metabolic

17. Bubble Formation at a Submerged Orifice in High-Speed Horizontal Oscillation

Wang, Ningzhen; Chen, Xiang; Yuan, Jianyu; Wang, Guiquan; Li, Yanxiang; Zhang, Huawei; Liu, Yuan

2016-12-01

Reducing the cell size of aluminum foams is always a hot and difficult topic in the fabrication of aluminum foams by gas injection route. There lacks theoretical guidance for the bubble size reduction when foaming by the dynamic gas injection method. For the convenience of observation, the aqueous bubbles from small-sized orifice in the high-speed horizontal oscillation were investigated in this paper. A bubble formation and detachment model in the high-speed horizontal oscillation system was proposed. The high-speed system with horizontal simple harmonic oscillation could reduce the average bubble size of aqueous foam effectively. The regularity of bubble formation and the influence of experimental parameters on average bubble size can be predicted by the theoretical model, and the experimental results agree well with the theoretical calculation. The results have shown that bubbles generally detach from the orifice at deceleration periods of the simple harmonic oscillation, and there exist several fixed sizes of bubbles with the fixed experimental parameters due to the effects of periodic forces. The average bubble size decreases with the increase of oscillation frequency and amplitude, and it roughly increases with the increase of gas flow rate. Using the high-speed horizontal oscillation method to prepare aluminum foams, the cell size can be reduced to about 1 mm. Moreover, the cell sizes of aluminum foam can be well predicted by this theoretical model.

18. High Amplitude Acoustic Behavior of a Slit-Orifice Backed by a Cavity

NASA Technical Reports Server (NTRS)

Ahuja, K. K.; Gaeta, R. J., Jr.; DAgostino, M.

2000-01-01

The objective of this study was to acquire detailed acoustic data and limited flow visualization data for numerical validation of a new model of sound absorption by a very narrow rectangular slit backed by a cavity. The sound absorption model is that being developed by Dr. C. K. W. Tam of Florida State University. This report documents normal incidence impedance measurements of a singular rectangular slit orifice with no mean flow. All impedance measurements are made within a 1.12 inch (28.5 mm) diameter impedance tube using the two-microphone method for several frequencies in the range 1000 - 6000Hz and incident sound pressure levels in the range 130 - 150 dB. In the interest of leaving the analysis of the data to the developers of more advanced Analytical and computational models of sound absorption by narrow slits, we authors have refrained from giving our own explanations of the observed results, although many of the observed results can be explained using the classical understanding of sound absorption by orifices.

19. High Amplitude Acoustic Behavior of a Slit-Orifice Backed by a Cavity

NASA Technical Reports Server (NTRS)

Ahuja, K. K.; Gaeta, R. J., Jr.; DAgostino, M.; Jones, Mike (Technical Monitor)

2000-01-01

The objective of the study reported here was to acquire detailed acoustic data and limited and flow visualization data for numerical validation a new model of sound absorption by a very narrow rectangular slit backed by a cavity. The sound absorption model is being developed by Dr. C. K. W. Tam of Florida State University. This report documents normal incidence impedance measurements of a singular rectangular slit orifice with no mean flow. All impedance measurements are made within a 1.12 inch (28.5 mm) diameter impedance tube using the two-microphone method for several frequencies in the range 1000-6000Hz and incident sound pressure levels in the range 130 - 150 dB. In the interest of leaving the analysis of the data to the developers of more advanced analytical and computational models of sound absorption by narrow slits, we have refrained from giving our own explanations of the observed results, although many of the observed results can be explained using the classical explanations of sound absorption by orifices.

20. Dynamical modeling of pulsed two-photon interference

Fischer, Kevin A.; Müller, Kai; Lagoudakis, Konstantinos G.; Vučković, Jelena

2016-11-01

Single-photon sources are at the heart of quantum-optical networks, with their uniquely quantum emission and phenomenon of two-photon interference allowing for the generation and transfer of nonclassical states. Although a few analytical methods have been briefly investigated for describing pulsed single-photon sources, these methods apply only to either perfectly ideal or at least extremely idealized sources. Here, we present the first complete picture of pulsed single-photon sources by elaborating how to numerically and fully characterize non-ideal single-photon sources operating in a pulsed regime. In order to achieve this result, we make the connection between quantum Monte-Carlo simulations, experimental characterizations, and an extended form of the quantum regression theorem. We elaborate on how an ideal pulsed single-photon source is connected to its photocount distribution and its measured degree of second- and first-order optical coherence. By doing so, we provide a description of the relationship between instantaneous source correlations and the typical experimental interferometers (Hanbury-Brown and Twiss, Hong-Ou-Mandel, and Mach-Zehnder) used to characterize such sources. Then, we use these techniques to explore several prototypical quantum systems and their non-ideal behaviors. As an example numerical result, we show that for the most popular single-photon source—a resonantly excited two-level system—its error probability is directly related to its excitation pulse length. We believe that the intuition gained from these representative systems and characters can be used to interpret future results with more complicated source Hamiltonians and behaviors. Finally, we have thoroughly documented our simulation methods with contributions to the Quantum Optics Toolbox in Python in order to make our work easily accessible to other scientists and engineers.

1. A three-pulse model of d. c. side harmonic flow in HVDC systems

SciTech Connect

Shore, N.L.; Andersson, G.; Canelhas, A.P.; Asplund, G.

1989-07-01

A new model for analysis of d.c. side harmonics in HVDC systems is proposed. The model includes the stray capacitances of converter transformers and bushings and represents the 12-pulse converter as four three-pulse harmonic voltage sources. The appearance of ground mode triplen harmonics of troublesome magnitude in pole and electrode lines, as noted in recent site measurements, is explained, as is the increase in magnitude of the characteristic 12-pulse harmonics. The consequences for d.c. filter design and the specification of telephone interference criteria are also discussed.

2. Effects of Pulsed Electromagnetic Fields on Osteoporosis Model

Xiaowei, Yang; Liming, Wang; Guan, Z. C.; Yaou, Zhang; Xiangpeng, Wang

The purpose of this paper was to investigate the preventive effects and long term effects of extremely low frequency pulsed electromagnetic fields (PEMFs), generated by circular coils and pulsed electromagnetic fields stimulators, on osteoporosis in bilaterally ovariectomized rats. In preventive experiment, thirty three-month old female Sprague-Dawley rats were randomly divided into three different groups: sham (SHAM), ovariectomy (OVX), PEMFs stimulation (PEMFs). All rats were subjected to bilaterally ovariectomy except those in SHAM group. The PEMFs group was exposed to pulsed electromagnetic fields with frequency 15 Hz, peak magnetic induction density 2.2mT and exposure time 2 hours per day. The bone mineral density (BMD) of vertebra and left femur were measured by dual energy X-ray absorptiometry at eighth week, twelfth week and sixteenth week after surgery. In long term effects experiment, forty four rats were randomly divided into sham (14 rats, SHAM), ovariectomy group (10 rats, OVX), 15Hz PEMFs group(10 rats, 15Hz) and 30Hz PEMFs group(10 rats, 30Hz) at twenty-sixth week after surgery. Rats in PEMFs groups were stimulated sixteen weeks. In preventive experiment, the Corrected BMD of vertebra and femur was significantly higher than that of OVX group after 16 weeks (P<0.001, P<0.001 respectively). In long term effects experiment, the vertebral BMD of 15Hz PEMFs group and 30Hz PEMFs group was significantly higher than that of OVX groups (P<0.01, P<0.05 respectively). The experimental results demonstrated that extremely low intensity, low frequency, single pulsed electromagnetic fields significantly slowed down the loss of corrected vertebral and femoral BMD in bilaterally ovariectomized rats and suggest that PEMFs may be beneficial in the treatment of osteoporosis.

3. Modeling of dielectric barrier discharge plasma actuators driven by repetitive nanosecond pulses

SciTech Connect

Likhanskii, Alexandre V.; Shneider, Mikhail N.; Macheret, Sergey O.; Miles, Richard B.

2007-07-15

A detailed physical model for an asymmetric dielectric barrier discharge (DBD) in air driven by repetitive nanosecond voltage pulses is developed. In particular, modeling of DBD with high voltage repetitive negative and positive nanosecond pulses combined with positive dc bias is carried out. Operation at high voltage is compared with operation at low voltage, highlighting the advantage of high voltages, however the effect of backward-directed breakdown in the case of negative pulses results in a decrease of the integral momentum transferred to the gas. The use of positive repetitive pulses with dc bias is demonstrated to be promising for DBD performance improvement. The effects of the voltage waveform not only on force magnitude, but also on the spatial profile of the force, are shown. The crucial role of background photoionization in numerical modeling of ionization waves (streamers) in DBD plasmas is demonstrated.

4. An Acoustic Demonstration Model for CW and Pulsed Spectrosocopy Experiments

Starck, Torben; Mäder, Heinrich; Trueman, Trevor; Jäger, Wolfgang

2009-06-01

High school and undergraduate students have often difficulties if new concepts are introduced in their physics or chemistry lectures. Lecture demonstrations and references to more familiar analogues can be of great help to the students in such situations. We have developed an experimental setup to demonstrate the principles of cw absorption and pulsed excitation - emission spectroscopies, using acoustical analogues. Our radiation source is a speaker and the detector is a microphone, both controlled by a computer sound card. The acoustical setup is housed in a plexiglas box, which serves as a resonator. It turns out that beer glasses are suitable samples; this also helps to keep the students interested! The instrument is controlled by a LabView program. In a cw experiment, the sound frequency is swept through a certain frequency range and the microphone response is recorded simultaneously as function of frequency. A background signal without sample is recorded, and background subtraction yields the beer glass spectrum. In a pulsed experiment, a short sound pulse is generated and the microphone is used to record the resulting emission signal of the beer glass. A Fourier transformation of the time domain signal gives then the spectrum. We will discuss the experimental setup and show videos of the experiments.

5. Pulse Tube Refrigerator

Matsubara, Yoichi

The pulse tube refrigerator is one of the regenerative cycle refrigerators such as Stirling cycle or Gifford-McMahon cycle which gives the cooling temperature below 150 K down to liquid helium temperature. In 1963, W. E. Gifford invented a simple refrigeration cycle which is composed of compressor, regenerator and simple tube named as pulse tube which gives a similar function of the expander in Stirling or Gifford-McMahon cycle. The thermodynamically performance of this pulse tube refrigerator is inferior to that of other regenerative cycles. In 1984, however, Mikulin and coworkers made a significant advance in pulse tube configuration called as orifice pulse tube. After this, several modifications of the pulse tube hot end configuration have been developed. With those modifications, the thermodynamic performance of the pulse tube refrigerator became the same order to that of Stirling and Gifford-McMahon refrigerator. This article reviews the brief history of the pulse tube refrigerator development in the view point of its thermodynamically efficiency. Simplified theories of the energy flow in the pulse tube have also been described.

6. Modelling the effects of pulse exposure of several PSII inhibitors on two algae.

PubMed

Copin, Pierre-Jean; Chèvre, Nathalie

2015-10-01

Subsequent to crop application and during precipitation events, herbicides can reach surface waters in pulses of high concentrations. These pulses can exceed the Annual Average Environmental Quality Standards (AA-EQS), defined in the EU Water Framework Directive, which aims to protect the aquatic environment. A model was developed in a previous study to evaluate the effects of pulse exposure for the herbicide isoproturon on the alga Scenedesmus vacuolatus. In this study, the model was extended to other substances acting as photosystem II inhibitors and to other algae. The measured and predicted effects were equivalent when pulse exposure of atrazine and diuron were tested on S. vacuolatus. The results were consistent for isoproturon on the alga Pseudokirchneriella subcapitata. The model is thus suitable for the effect prediction of phenylureas and triazines and for the algae used: S. vacuolatus and P. subcapitata. The toxicity classification obtained from the dose-response curves (diuron>atrazine>isoproturon) was conserved for the pulse exposure scenarios modelled for S. vacuolatus. Toxicity was identical for isoproturon on the two algae when the dose-response curves were compared and also for the pulse exposure scenarios. Modelling the effects of any pulse scenario of photosystem II inhibitors on algae is therefore feasible and only requires the determination of the dose-response curves of the substance and growth rate of unexposed algae. It is crucial to detect the longest pulses when measurements of herbicide concentrations are performed in streams because the model showed that they principally affect the cell density inhibition of algae.

7. Characterization of surface position in a liquid dispensing orifice

SciTech Connect

Farahi, R H; Passian, Ali; Thundat, Thomas George; Lereu, Aude L; Tetard, Laurene; Jones, Yolanda

2009-01-01

Precision microdispencing technology delivers picoliter amounts of fluid for printing, electronic, optical, chemical and biomedical applications. In particular, microjetting is capable of accurate, flexible, and non-contact coating with polymers, thus allowing the functionalization of delicate microsensors such as microcantilevers. Information on various phases of droplet formation are important to control volume, uniformity, velocity and rate. One such aspect is the ringing of the meniscus after droplet breakoff which can affect subsequent drop formation. We present analysis of an optical characterization technique and experimental results on the behaviour of menisus oscillations in an orifice of a piezoelectric microjet.

8. Fast measurements of flow through mitral regurgitant orifices with magnetic resonance phase velocity mapping.

PubMed

Zhang, Haosen; Halliburton, Sandra S; White, Richard D; Chatzimavroudis, George P

2004-12-01

Magnetic-resonance (MR) phase velocity mapping (PVM) shows promise in measuring the mitral regurgitant volume. However, in its conventional nonsegmented form, MR-PVM is slow and impractical for clinical use. The aim of this study was to evaluate the accuracy of rapid, segmented k-space MR-PVM in quantifying the mitral regurgitant flow through a control volume (CV) method. Two segmented MR-PVM schemes, one with seven (seg-7) and one with nine (seg-9) lines per segment, were evaluated in acrylic regurgitant mitral valve models under steady and pulsatile flow. A nonsegmented (nonseg) MR-PVM acquisition was also performed for reference. The segmented acquisitions were considerably faster (<10 min) than the nonsegmented (>45 min). The regurgitant flow rates and volumes measured with segmented MR-PVM agreed closely with those measured with nonsegmented MR-PVM (differences <5%, p > 0.05), when the CV was large enough to exclude the region of flow acceleration and aliasing from its boundaries. The regurgitant orifice shape (circular vs. slit-like) and the presence of aortic outflow did not significantly affect the accuracy of the results under both steady and pulsatile flow (p > 0.05). This study shows that segmented k-space MR-PVM can accurately quantify the flow through regurgitant orifices using the CV method and demonstrates great clinical potential.

9. Computationally efficient method for Fourier transform of highly chirped pulses for laser and parametric amplifier modeling.

PubMed

Andrianov, Alexey; Szabo, Aron; Sergeev, Alexander; Kim, Arkady; Chvykov, Vladimir; Kalashnikov, Mikhail

2016-11-14

We developed an improved approach to calculate the Fourier transform of signals with arbitrary large quadratic phase which can be efficiently implemented in numerical simulations utilizing Fast Fourier transform. The proposed algorithm significantly reduces the computational cost of Fourier transform of a highly chirped and stretched pulse by splitting it into two separate transforms of almost transform limited pulses, thereby reducing the required grid size roughly by a factor of the pulse stretching. The application of our improved Fourier transform algorithm in the split-step method for numerical modeling of CPA and OPCPA shows excellent agreement with standard algorithms.

10. Computational model for time development of the EM field in pulsed laser systems

Skrabelj, D.; Marincek, M.; Drevensek-Olenik, I.; Leskovar, M.; Copic, M.

2007-05-01

A computational model, which describes EM field formation in a pulsed laser from a randomly generated initial spontaneous field inside the laser cavity has been developed. The model is based on a two-dimensional fast Fourier transform and describes a real laser system taking into account a lensing and a diaphragm effect of the laser rod. The laser cavity is described by five effective planes, which represent different laser cavity elements-the back and the front mirror, the Q-switch element and the laser rod. At each plane the EM field is calculated in real space and propagation between the planes is achieved in Fourier space by multiplication with an appropriate phase factor. The computational time needed for simulation of a realistic pulse formation is in order of minutes. The model can predict the shape and the integral energy of the pulse, its transverse profile at different distances from the front mirror (including near and far field) and beam divergence. The results of the model were found to be in good agreement with measured parameters for a Q-switched ruby laser system running in stable as well as unstable cavity configurations. The temporal shape of a laser pulse was measured and calculated not only for the ruby laser, but also for a Nd:YAG laser. It was found that FWHM of a pulse produced by ruby laser is three times longer than FWHM of a pulse produced by Nd:YAG laser.

11. On the performance and flow characteristics of jet pumps with multiple orifices.

PubMed

Oosterhuis, Joris P; Timmer, Michael A G; Bühler, Simon; van der Meer, Theo H; Wilcox, Douglas

2016-05-01

The design of compact thermoacoustic devices requires compact jet pump geometries, which can be realized by employing jet pumps with multiple orifices. The oscillatory flow through the orifice(s) of a jet pump generates asymmetric hydrodynamic end effects, which result in a time-averaged pressure drop that can counteract Gedeon streaming in traveling wave thermoacoustic devices. In this study, the performance of jet pumps having 1-16 orifices is characterized experimentally in terms of the time-averaged pressure drop and acoustic power dissipation. Upon increasing the number of orifices, a significant decay in the jet pump performance is observed. Further analysis shows a relation between this performance decay and the diameter of the individual holes. Possible causes of this phenomenon are discussed. Flow visualization is used to study the differences in vortex ring interaction from adjacent jet pump orifices. The mutual orifice spacing is varied and the corresponding jet pump performance is measured. The orifice spacing is shown to have less effect on the jet pump performance compared to increasing the number of orifices.

12. A review of pulse tube refrigeration

NASA Technical Reports Server (NTRS)

1990-01-01

This paper reviews the development of the three types of pulse tube refrigerators: basic, resonant, and orifice types. The principles of operation are given. It is shown that the pulse tube refrigerator is a variation of the Stirling-cycle refrigerator, where the moving displacer is substituted by a heat transfer mechanism or by an orifice to bring about the proper phase shifts between pressure and mass flow rate. A harmonic analysis with phasors is described which gives reasonable results for the refrigeration power, yet is simple enough to make clear the processes which give rise to the refrigeration. The efficiency and refrigeration power are compared with those of other refrigeration cycles. A brief review is given of the research being done at various laboratories on both one- and two-stage pulse tubes. A preliminary assessment of the role of pulse tube refrigerators is discussed.

13. A review of pulse tube refrigeration

This paper reviews the development of the three types of pulse tube refrigerators: basic, resonant, and orifice types. The principles of operation are given. It is shown that the pulse tube refrigerator is a variation of the Stirling-cycle refrigerator, where the moving displacer is substituted by a heat transfer mechanism or by an orifice to bring about the proper phase shifts between pressure and mass flow rate. A harmonic analysis with phasors is described which gives reasonable results for the refrigeration power, yet is simple enough to make clear the processes which give rise to the refrigeration. The efficiency and refrigeration power are compared with those of other refrigeration cycles. A brief review is given of the research being done at various laboratories on both one- and two-stage pulse tubes. A preliminary assessment of the role of pulse tube refrigerators is discussed.

14. Pulsating-flow measurement with an orifice flange

Bossart, L. M.

1981-05-01

A measurement problem encountered during instrumentation of a geothermal air drilling operation on the Baca Ranch in the Jemez Mountains in New Mexico was how to measure the flow of ammonia water solution injected into the air line. The pump that develops the pressure in the ammonia line is not a positive displacement pump, therefore, counting pump strokes does not determine the number of gal/min of ammonia flow. The flow was measured using an orifice flange differential pressure technique but, the range of flow measured, exceeded the 4:1 range ability of an orifice. A computer smoothing of the differential pressure and the line pressure together with a scaling factor, determined by the shape of the raw differential pressure, provided a smoothing of the flow data which was checked against the actual flow over a long time period to determine the volume of solution injected into the system per hour. An instantaneous reading of ammonia flow was thereby determined. It showed small variations in corrosion rate measured in the standpipe that may have been caused by a momentary variation in the flow of ammonia solution.

15. [A current perspective of natural orifices transluminal endoscopic surgery (NOTES)].

PubMed

Montalvo-Javé, Eduardo E; Crisanto-Campos, Braulio A; Tapia-Jurado, Jesús; Montes de Oca-Duran, Edgar; Ortega-León, Luis Humberto; Alcántara-Medina, Stefany; Mendoza-Barrera, German Eduardo; Athie Gutierrez, César

2016-01-01

Natural orifice transluminal endoscopic surgery (NOTES) represents an alternative in surgical approach, combined with the progress and experience gained from conventional and endoscopic surgery. Bibliographic research in PubMed, Medline database from 2000 to 2015 and analysis of the literature reviews found. NOTES provides vision and natural orifice approach, it has optimized operating times as well as reduced complications and better cosmetic results. Small series of patients have been reported, but there is not a valid clinical multicenter study by evidence-based medicine. NOTES can help to improve the standard operations, complemented with laparoscopic surgery rather than replace it and thus develop tools for the resolution of various diseases that require surgical treatment. This option in current surgery is safe and presents satisfactory results in the reported cases. The development of this new approach of performing surgical procedures requires further study and development of new technology in order to increase the accessibility of these procedures and represent in a practical and sustained way, a better option to approach surgical pathology.

16. Adjustable steam producing flexible orifice independent of fluid pressure

NASA Technical Reports Server (NTRS)

Morrison, Andrew D. (Inventor)

1992-01-01

A self-adjusting choke for a fluids nozzle includes a membrane constructed of a single piece of flexible or elastic material. This flexible material is shaped to fit into the outlet of a nozzle. The body of the membrane has at least two flow channels, from one face to the other, which directs two streams of water to cross at the opening of the nozzle or at some point beyond. The elasticity and thickness of the membrane is selected to match the range of expected pressures and fluid velocities. The choke may have more than two flow channels, as long as they are aligned adjacent to one another and directed towards each other at the exit face. In a three orifice embodiment, one is directed upward, one is directed downward, and the one in the middle is directed forward. In this embodiment all three fluid streams intersect at some point past the nozzle opening. Under increased pressure the membrane will deform causing the orifices to realign in a more forward direction, causing the streams to intersect at a smaller angle. This reduces the force with which the separate streams impact each other, still allowing the separate streams to unify into a single stable spiralling stream in spite of the increased pressure.

17. Incorporation of a Variable Discharge Coefficient for the Primary Orifice into the Benet Labs Recoil Analysis Model via Results from Quasi-Steady State Simulations Using Computational Fluid Dynamics

DTIC Science & Technology

2008-03-01

function, its value at zero time is indeterminate; however, by using techniques of calculus , it is found to be zero. The third is the 3 parameter Hill...cavitation and collapse of the fluid. Based on these results, it makes sense that the application of CFD modeling for an incompressible Newtonian fluid...regard to execution time. In addition the trend is non -linear in that the time increases by a factor of 70 from the smallest to the largest ratio and

18. Reproduction of Consistent Pulse-Waveform Changes Using a Computational Model of the Cerebral Circulatory System

PubMed Central

Connolly, Mark; He, Xing; Gonzalez, Nestor; Vespa, Paul; DiStefano, Joe; Hu, Xiao

2014-01-01

Due to the inaccessibility of the cranial vault, it is difficult to study cerebral blood flow dynamics directly. A mathematical model can be useful to study these dynamics. The model presented here is a novel combination of a one-dimensional fluid flow model representing the major vessels of the circle of Willis (CoW), with six individually parameterized auto-regulatory models of the distal vascular beds. This model has the unique ability to simulate high temporal resolution flow and velocity waveforms, amenable to pulse-waveform analysis, as well as sophisticated phenomena such as auto-regulation. Previous work with human patients has shown that vasodilation induced by CO2 inhalation causes 12 consistent pulse-waveform changes as measured by the Morphological Clustering and Analysis of Intracranial Pressure algorithm. To validate this model, we simulated vasodilation and successfully reproduced 9 out of the 12 pulse-waveform changes. A subsequent sensitivity analysis found that these 12 pulse-waveform changes were most affected by the parameters associated with the shape of the smooth muscle tension response and vessel elasticity, providing insight into the physiological mechanisms responsible for observed changes in the pulse-waveform shape. PMID:24389244

19. Reproduction of consistent pulse-waveform changes using a computational model of the cerebral circulatory system.

PubMed

Connolly, Mark; He, Xing; Gonzalez, Nestor; Vespa, Paul; DiStefano, Joe; Hu, Xiao

2014-03-01

Due to the inaccessibility of the cranial vault, it is difficult to study cerebral blood flow dynamics directly. A mathematical model can be useful to study these dynamics. The model presented here is a novel combination of a one-dimensional fluid flow model representing the major vessels of the circle of Willis (CoW), with six individually parameterized auto-regulatory models of the distal vascular beds. This model has the unique ability to simulate high temporal resolution flow and velocity waveforms, amenable to pulse-waveform analysis, as well as sophisticated phenomena such as auto-regulation. Previous work with human patients has shown that vasodilation induced by CO2 inhalation causes 12 consistent pulse-waveform changes as measured by the morphological clustering and analysis of intracranial pressure algorithm. To validate this model, we simulated vasodilation and successfully reproduced 9 out of the 12 pulse-waveform changes. A subsequent sensitivity analysis found that these 12 pulse-waveform changes were most affected by the parameters associated with the shape of the smooth muscle tension response and vessel elasticity, providing insight into the physiological mechanisms responsible for observed changes in the pulse-waveform shape.

20. Ballistic and Diffuse Ultrafast Laser Pulses Propagation in Model Random Media and Biological Tissues

Liu, Feng

The goal of this thesis is to study light scattering and ultrashort laser pulse propagation in the model discrete random media and biological tissues. The temporal profiles of the scattered ultrashort laser pulses were measured by using ultrashort laser pulses, streak camera with 10 ps time response and the femtosecond cross correlation technique. The intensity of the diffuse pulse is found to be preferentially reduced by the absorption with respect to the intensity of the ballistic light because the diffuse light on the average travel through a longer path than the ballistic light. A simple experiment was performed to demonstrate that one can image through a highly scattering medium by increasing the absorption in the medium. The speed of the ballistic pulse was measured by the femtosecond second harmonic cross correlation method and was found to be reduced by the scattering. This speed reduction can be accounted for by the volume fraction combination of the indices of refraction of the scatterers and the water or by the coherent interference between the scattered waves and the primary wave. No distinct ballistic pulse was observed when the laser pulse transmitted through a thin tissue. The continuous random variation of the dielectric constant in tissue may account for the lack of a distinct ballistic pulse. Nevertheless, the early arriving portion of the transmitted pulse was shown to carry image information. The earlier arriving photons were found to produce image of the hidden object with better quality. The intensity of the early arriving transmitted photons was found to decay exponentially with increasing tissue thickness. The earlier the photons arrive, the quicker their intensity decay. Diffusion theory was found to describe the overall transmitted pulse profiles well, but it underestimates the intensity of the early arriving photons. Compressing tissue was found not to change the key optical parameters of the tissue. The scattered laser pulse profile in

1. AxBAxB… pulsed atomic layer deposition: Numerical growth model and experiments

2016-02-01

Atomic layer deposition (ALD) is widely used for the fabrication of advanced semiconductor devices and related nanoscale structures. During ALD, large precursor doses (>1000 L per pulse) are often required to achieve surface saturation, of which only a small fraction is utilized in film growth while the rest is pumped from the system. Since the metal precursor constitutes a significant cost of ALD, strategies to enhance precursor utilization are essential for the scaling of ALD processes. In the precursor reaction step, precursor physisorption is restricted by steric hindrance (mA1) from ligands on the precursor molecules. On reaction, some of these ligands are removed as by-products resulting in chemisorbed species with reduced steric hindrance (mA1 → mA2, where mA2 < mA1) and some of the initially hindered surface reaction sites becoming accessible for further precursor physisorption. To utilize these additional reaction sites, we propose a generalized AxBAxB… pulsed deposition where the total precursor dose (ΦA) is introduced as multiple x (x > 1, x ∈ I) short-pulses rather than a single pulse. A numerical first-order surface reaction kinetics growth model is presented and applied to study the effect of AxBAxB… pulsed ALD on the growth per cycle (GPC). The model calculations predict higher GPC for AxBAxB… pulsing than with ABAB… deposition. In agreement with the model predictions, with AxBAxB… pulsed deposition, the GPC was found to increase by ˜46% for ZrN plasma enhanced ALD (PEALD), ˜49% for HfO2 PEALD, and ˜8% for thermal Al2O3 ALD with respect to conventional ABAB… pulsed growth.

2. Evaluation of pulsed high intensity focused ultrasound exposures on metastasis in a murine model

PubMed Central

Hancock, Hilary; Dreher, Matthew R.; Crawford, Nigel; Pollock, Claire B.; Shih, Jennifer; Wood, Bradford J.; Hunter, Kent; Frenkel, Victor

2014-01-01

High intensity focused ultrasound (HIFU) may be employed in two ways: continuous exposures for thermal ablation of tissue (>60°C), and pulsed-exposures for non-ablative effects, including low temperature hyperthermia (37–45°C), and non thermal effects (e.g. acoustic cavitation and radiation forces). Pulsed-HIFU effects may enhance the tissue's permeability for improved delivery of drugs and genes, for example, by opening up gaps between cells in the vasculature and parenchyma. Inducing these effects may improve local targeting of therapeutic agents, however; concerns exist that pulsed exposures could theoretically also facilitate dissemination of tumor cells and exacerbate metastases. In the present study, the influence of pulsed-HIFU exposures on increasing metastatic burden was evaluated in a murine model with metastatic breast cancer. A preliminary study was carried out to validate the model and determine optimal timing for treatment and growth of lung metastases. Next, the effect of pulsed-HIFU on the metastatic burden was evaluated using quantitative image processing of whole-lung histological sections. Compared to untreated controls (2/15), a greater number of mice treated with pulsed-HIFU were found to have lungs “overgrown” with metastases (7/15), where individual metastases grew together such that they could not accurately be counted. Furthermore, area fraction of lung metastases (area of metastases/area of lungs) was ~30% greater in mice treated with pulsed-HIFU; however, these differences were not statistically significant. The present study details the development of an animal model for investigating the influence of interventional techniques or exposures (such as pulsed HIFU) on metastatic burden. PMID:19517258

3. Numerical study of a macroscopic finite pulse model of the diffusion MRI signal.

PubMed

Li, Jing-Rebecca; Nguyen, Hang Tuan; Nguyen, Dang Van; Haddar, Houssem; Coatléven, Julien; Le Bihan, Denis

2014-11-01

Diffusion magnetic resonance imaging (dMRI) is an imaging modality that probes the diffusion characteristics of a sample via the application of magnetic field gradient pulses. The dMRI signal from a heterogeneous sample includes the contribution of the water proton magnetization from all spatial positions in a voxel. If the voxel can be spatially divided into different Gaussian diffusion compartments with inter-compartment exchange governed by linear kinetics, then the dMRI signal can be approximated using the macroscopic Karger model, which is a system of coupled ordinary differential equations (ODEs), under the assumption that the duration of the diffusion-encoding gradient pulses is short compared to the diffusion time (the narrow pulse assumption). Recently, a new macroscopic model of the dMRI signal, without the narrow pulse restriction, was derived from the Bloch-Torrey partial differential equation (PDE) using periodic homogenization techniques. When restricted to narrow pulses, this new homogenized model has the same form as the Karger model. We conduct a numerical study of the new homogenized model for voxels that are made up of periodic copies of a representative volume that contains spherical and cylindrical cells of various sizes and orientations and show that the signal predicted by the new model approaches the reference signal obtained by solving the full Bloch-Torrey PDE in O(ε(2)), where ε is the ratio between the size of the representative volume and a measure of the diffusion length. When the narrow gradient pulse assumption is not satisfied, the new homogenized model offers a much better approximation of the full PDE signal than the Karger model. Finally, preliminary results of applying the new model to a voxel that is not made up of periodic copies of a representative volume are shown and discussed.

4. Determination of modeling parameters for power IGBTs under pulsed power conditions

SciTech Connect

Dale, Gregory E; Van Gordon, Jim A; Kovaleski, Scott D

2010-01-01

While the power insulated gate bipolar transistor (IGRT) is used in many applications, it is not well characterized under pulsed power conditions. This makes the IGBT difficult to model for solid state pulsed power applications. The Oziemkiewicz implementation of the Hefner model is utilized to simulate IGBTs in some circuit simulation software packages. However, the seventeen parameters necessary for the Oziemkiewicz implementation must be known for the conditions under which the device will be operating. Using both experimental and simulated data with a least squares curve fitting technique, the parameters necessary to model a given IGBT can be determined. This paper presents two sets of these seventeen parameters that correspond to two different models of power IGBTs. Specifically, these parameters correspond to voltages up to 3.5 kV, currents up to 750 A, and pulse widths up to 10 {micro}s. Additionally, comparisons of the experimental and simulated data will be presented.

5. Simple model for the effectiveness of PDT with pulsed-laser sources

Huettmann, Gereon; Heck, Ansgar; Diddens, Heyke C.

1994-08-01

Irradiation with pulsed lasers can change mechanisms and efficacy of photodynamic therapy (PDT) depending on the laser pulse parameters. Since most photosensitizers have a relatively high triplet quantum yield and triplet lifetimes of tens of microseconds, even moderate power densities below 100 kW/cm2 can lead to a saturation of the singlet oxygen production, thereby reducing the PDT effect. A simple quantitative model is developed to estimate this effect. According to this, for laser pulses not longer than the triplet lifetime, the PDT efficacy depends on the product of single pulse energy, irradiation wavelength, and the extinction coefficient of the photosensitizer. Peak irradiance and pulse width have minor influence on the efficacy of pulsed irradiation, which decreases as the triplet quantum yield reaches one. The model is supported by in vitro experiments with Photosan 3 and in vivo and in vitro experiments with Photosan 3, Photofrin, aluminum sulphonated phthalocyanine (AlSPc) and benzoporphyrin derivative monoacid ring A (BPD-MA) reported in the literature.

6. An improved three-dimensional two-temperature model for multi-pulse femtosecond laser ablation of aluminum

SciTech Connect

Zhang, Jinping; Chen, Yuping Hu, Mengning; Chen, Xianfeng

2015-02-14

In this paper, an improved three-dimensional two-temperature model for multi-pulse femtosecond laser ablation of aluminum was proposed and proved in our experiment. Aiming to achieve hole-drilling with a high ratio of depth/entrance diameter in vacuum, this model can predict the depth and radius of the drilled holes precisely when employing different laser parameters. Additionally, for multi-pulse laser ablation, we found that the laser fluence and number of pulses are the dominant parameters and the multi-pulse ablation threshold is much lower than the single-pulse one, which will help to obtain high-quality holes.

7. Novel Totally Laparoscopic Endolumenal Rectal Resection With Transanal Natural Orifice Specimen Extraction (NOSE) Without Rectal Stump Opening: A Modification of Our Recently Published Clean Surgical Technique in a Porcine Model.

PubMed

Kvasha, Anton; Hadary, Amram; Biswas, Seema; Szvalb, Sergio; Willenz, Udi; Waksman, Igor

2015-06-01

Our group has recently described a novel technique for clean endolumenal bowel resection, in which abdominal and transanal approaches were used. In the current study, 2 modifications of this procedure were tested for feasibility in a porcine model. A laparoscopic approach to the peritoneal cavity was employed in rectal mobilization; this was followed by a transanal rectorectal intussusception and pull-through (IPT). IPT was established in a stepwise fashion. First, the proximal margin of resection was attached to the shaft of the anvil of an end-to-end circular stapler with a ligature around the rectum. Second, this complex was pulled transanally to produce IPT. Once IPT was established, a second ligature was placed around the rectum approximating the proximal and distal resection margins. This was followed by a purse string suture through 2 bowel walls, encircling the shaft of the anvil just proximal to the ligatures. The specimen was resected and extracted by making a full-thickness incision through the 2 bowel walls distal to the previously placed purse string suture and ligatures. The anastomosis was achieved by applying the stapler. The technique was found to be feasible. Peritoneal samples, collected after transanal specimen extraction, did not demonstrate bacterial growth. Although, this is a novel and evolving procedure, its minimally invasive nature, as well as aseptic bowel manipulation during endolumenal rectal resection, has the potential to limit the complications associated with abdominal wall incision and surgical site infection.

8. Simulation of the electrically stimulated cochlear neuron: modeling adaptation to trains of electric pulses.

PubMed

Woo, Jihwan; Miller, Charles A; Abbas, Paul J

2009-05-01

9. Modeling and analysis of the HPM pulse-width upset effect on CMOS inverter

Xinhai, Yu; Changchun, Chai; Liping, Qiao; Yintang, Yang; Yang, Liu; Xiaowen, Xi

2015-05-01

We derive analytical models of the excess carrier density distribution and the HPM (high-power microwave) upset susceptibility with dependence of pulse-width, which are validated by the simulated results and experimental data. Mechanism analysis and model derivation verify that the excess carriers dominate the current amplification process of the latch-up. Our results reveal that the excess carrier density distribution in P-substrate behaves as pulse-width dependence. The HPM upset voltage threshold Vp decreases with the incremental pulse-width, while there is an inflection point which is caused because the excess carrier accumulation in the P-substrate will be suppressed over time. For the first time, the physical essence of the HPM pulse-width upset effect is proposed to be the excess carrier accumulation effect. Validation concludes that the Vp model is capable of giving a reliable and accurate prediction to the HPM upset susceptibility of a CMOS inverter, which simultaneously considers technology information, ambient temperature, and layout parameters. From the model, the layout parameter LB has been demonstrated to have a significant impact on the pulse-width upset effect: a CMOS inverter with minor LB is more susceptible to HPM, which enables us to put forward hardening measures for inverters that are immune from the HPM upset. Project supported by the National Natural Science Foundation of China (No. 60776034) and the State Key Development Program for Basic Research of China (No. 2014CB339900).

10. Microdosimetric study for nanosecond pulsed electric fields on a cell circuit model with nucleus.

PubMed

Denzi, Agnese; Merla, Caterina; Camilleri, Paola; Paffi, Alessandra; d'Inzeo, Guglielmo; Apollonio, Francesca; Liberti, Micaela

2013-10-01

Recently, scientific interest in electric pulses, always more intense and shorter and able to induce biological effects on both plasma and nuclear membranes, has greatly increased. Hence, microdosimetric models that include internal organelles like the nucleus have assumed increasing importance. In this work, a circuit model of the cell including the nucleus is proposed, which accounts for the dielectric dispersion of all cell compartments. The setup of the dielectric model of the nucleus is of fundamental importance in determining the transmembrane potential (TMP) induced on the nuclear membrane; here, this is demonstrated by comparing results for three different sets of nuclear dielectric properties present in the literature. The results have been compared, even including or disregarding the dielectric dispersion of the nucleus. The main differences have been found when using pulses shorter than 10 ns. This is due to the fact that the high spectral components of the shortest pulses are differently taken into account by the nuclear membrane transfer functions computed with and without nuclear dielectric dispersion. The shortest pulses are also the most effective in porating the intracellular structures, as confirmed by the time courses of the TMP calculated across the plasma and nuclear membranes. We show how dispersive nucleus models are unavoidable when dealing with pulses shorter than 10 ns because of the large spectral contents arriving above 100 MHz, i.e., over the typical relaxation frequencies of the dipolar mechanism of the molecules constituting the nuclear membrane and the subcellular cell compartments.

11. Flow Coefficients for Orifices in Base of Transpiration-Cooled Turbine Rotor Blade

NASA Technical Reports Server (NTRS)

Donoughe, Patrick L.; Prasse, Ernst I.

1953-01-01

Static tests on a segment of a transpiration-cooled turbine rotor blade with a wire-cloth shell were conducted to determine the flow coefficients associated with some representative metering orifices. Average flow coefficients from 0.96 to 0.79 were obtained for orifices of 0.031 to 0.102 inch diameter.

12. Identification of whistling ability of a single hole orifice from an incompressible flow simulation

SciTech Connect

Lacombe, Romain; Moussou, Pierre

2012-07-01

Pure tone noise from orifices in pipe result from vortex shedding with lock-in. Acoustic amplification at the orifice is coupled to resonant condition to create self-sustained oscillations. One key feature of this phenomenon is hence the ability of an orifice to amplify acoustic waves in a given range of frequencies. Here a numerical investigation of the linear response of an orifice is undertaken, with the support of experimental data for validation. The study deals with a sharp edge orifice. Its diameter equals to 0.015 m and its thickness to 0.005 m. The pipe diameter is 0.030 m. An air flow with a Mach number 0.026 and a Reynolds number 18000 in the main pipe is present. At such a low Mach number; the fluid behavior can reasonably be described as locally incompressible. The incompressible Unsteady Reynolds Averaged Navier-Stokes (URANS) equations are solved with the help of a finite volume fluid mechanics software. The orifice is submitted to an average flow velocity, with superimposed small harmonic perturbations. The harmonic response of the orifice is the difference between the upstream and downstream pressures, and a straightforward calculation brings out the acoustic impedance of the orifice. Comparison with experiments shows that the main physical features of the whistling phenomenon are reasonably reproduced. (authors)

13. Unaccounted-for gas project. Measurement Task Force (orifice meter studies). Volume 2B. Final report

SciTech Connect

Godkin, B.J.; Robertson, J.D.; Wlasenko, R.G.; Cowgill, R.M.; Grinstead, J.R.

1990-06-01

The study was aimed at determining unaccounted-for (UAF) gas volumes resulting from operating Pacific Gas and Electric Co.'s transmission and distribution systems during 1987. Activities and methods are described and results are presented for research conducted on orifice meter accuracy. The Measurement Task Force determined that orifice metering inaccuracies were the largest single contributor to 1987 UAF.

14. Effect of slotted exit orifice on performance of plasma synthetic jet actuator

Zong, Haohua; Kotsonis, Marios

2017-03-01

This study experimentally investigates the influence of exit orifice shape on the performance characteristics of a three-electrode plasma synthetic jet actuator. High-speed Schlieren imaging system and phase-locked two-component PIV measurements are used for flowfield characterisation in quiescent conditions. Two actuator configurations with the same exit area but different exit orifice shape (round orifice and slot orifice) are studied. Results indicate a close correspondence between the shapes of the starting vortex ring with the shapes of the respective exit orifices. For the slot orifice, the elongated starting vortex ring gradually expands during propagation, while its ends become warped. A distinct K-H instability structure is observed, inducing continuous oscillation of the high-speed jet. Compared with the jet from the round orifice, the slot jet has a higher entrainment rate of surrounding air, thus resulting in a lower propagation velocity of the jet front. The exit velocity of PSJA within one period initially shows a rapid increase, then persists at a relatively high level (100-130 m/s), and finally drops with some small-scale oscillations. The oscillation amplitude is less than 10 m/s, and the oscillation period is approximately 600 µs. Under conditions of same exit area, orifice shape has little influence on the variation of the exit velocity.

15. Significance of gauge line error in orifice measurement

SciTech Connect

Bowen, J.W.

1995-12-01

Pulsation induced gauge line amplification can cause errors in the recorded differential signal used to calculate flow. Its presence may be detected using dual transmitters (one connected at the orifice taps, the other at the end of the gauge lines) and comparing the relative peak to peak amplitudes. Its affect on recorded differential may be determined by averaging both signals with a PC based data acquisition and analysis system. Remedial action is recommended in all cases where amplification is detected. Use of close connect, full opening manifolds, is suggested to decouple the gauge lines` resonant frequency from that of the excitation`s, by positioning the recording device as close to the process signal`s origin as possible.

16. Efficiently parallelized modeling of tightly focused, large bandwidth laser pulses

Dumont, Joey; Fillion-Gourdeau, François; Lefebvre, Catherine; Gagnon, Denis; MacLean, Steve

2017-02-01

The Stratton–Chu integral representation of electromagnetic fields is used to study the spatio-temporal properties of large bandwidth laser pulses focused by high numerical aperture mirrors. We review the formal aspects of the derivation of diffraction integrals from the Stratton–Chu representation and discuss the use of the Hadamard finite part in the derivation of the physical optics approximation. By analyzing the formulation we show that, for the specific case of a parabolic mirror, the integrands involved in the description of the reflected field near the focal spot do not possess the strong oscillations characteristic of diffraction integrals. Consequently, the integrals can be evaluated with simple and efficient quadrature methods rather than with specialized, more costly approaches. We report on the development of an efficiently parallelized algorithm that evaluates the Stratton–Chu diffraction integrals for incident fields of arbitrary temporal and spatial dependence. This method has the advantage that its input is the unfocused field coming from the laser chain, which is experimentally known with high accuracy. We use our method to show that the reflection of a linearly polarized Gaussian beam of femtosecond duration off a high numerical aperture parabolic mirror induces ellipticity in the dominant field components and generates strong longitudinal components. We also estimate that future high-power laser facilities may reach intensities of {10}24 {{W}} {{cm}}-2.

17. Modeling the network dynamics of pulse-coupled neurons

Chandra, Sarthak; Hathcock, David; Crain, Kimberly; Antonsen, Thomas M.; Girvan, Michelle; Ott, Edward

2017-03-01

We derive a mean-field approximation for the macroscopic dynamics of large networks of pulse-coupled theta neurons in order to study the effects of different network degree distributions and degree correlations (assortativity). Using the ansatz of Ott and Antonsen [Chaos 18, 037113 (2008)], we obtain a reduced system of ordinary differential equations describing the mean-field dynamics, with significantly lower dimensionality compared with the complete set of dynamical equations for the system. We find that, for sufficiently large networks and degrees, the dynamical behavior of the reduced system agrees well with that of the full network. This dimensional reduction allows for an efficient characterization of system phase transitions and attractors. For networks with tightly peaked degree distributions, the macroscopic behavior closely resembles that of fully connected networks previously studied by others. In contrast, networks with highly skewed degree distributions exhibit different macroscopic dynamics due to the emergence of degree dependent behavior of different oscillators. For nonassortative networks (i.e., networks without degree correlations), we observe the presence of a synchronously firing phase that can be suppressed by the presence of either assortativity or disassortativity in the network. We show that the results derived here can be used to analyze the effects of network topology on macroscopic behavior in neuronal networks in a computationally efficient fashion.

18. The Effect of Ionospheric Models on Electromagnetic Pulse Locations

SciTech Connect

Fenimore, Edward E.; Triplett, Laurie A.

2014-07-01

Locations of electromagnetic pulses (EMPs) determined by time-of-arrival (TOA) often have outliers with significantly larger errors than expected. In the past, these errors were thought to arise from high order terms in the Appleton-Hartree equation. We simulated 1000 events randomly spread around the Earth into a constellation of 22 GPS satellites. We used four different ionospheres: “simple” where the time delay goes as the inverse of the frequency-squared, “full Appleton-Hartree”, the “BobRD integrals” and a full raytracing code. The simple and full Appleton-Hartree ionospheres do not show outliers whereas the BobRD and raytracing do. This strongly suggests that the cause of the outliers is not additional terms in the Appleton-Hartree equation, but rather is due to the additional path length due to refraction. A method to fix the outliers is suggested based on fitting a time to the delays calculated at the 5 GPS frequencies with BobRD and simple ionospheres. The difference in time is used as a correction to the TOAs.

19. Application of Multi-Stage Orifices in Letdown System- Lessons Learned

SciTech Connect

Kim, Eun Kee; Kim, Chang Ho; Park, Jong Seob; Chung, Chang Kyu; Ro, Tae Sun; Park, Boo Sung

2002-07-01

Cavitation, vibration and severe noise in multi-stage orifice assemblies of the letdown system have been experienced during plant startup tests. Test results were reviewed and evaluated to investigate root causes for the problems. Root causes identified are design deficiencies and inadequate shop testing including improper test conditions and corrections. If conventional design criteria for single-stage orifice are applied directly to the design of multi-stage orifice assembly, unexpected problems might occur in the field. Discharge coefficients of multi-stage orifice showed to be significantly affected by Reynolds number, while empirical discharge coefficients of single-stage orifice were reported to be almost constant in turbulent regime. Some design considerations are recommended to avoid similar problems. (authors)

20. Natural Orifice Surgery: Transdouglas Surgery—a New Concept

PubMed Central

Stark, Michael

2008-01-01

Background: During the 20th century, laparoscopic procedures replaced most traditional abdominal operations and achieved high-quality standards. It seemed that the optimal surgical method had been achieved; however, a new concept, which might possibly become even safer and simpler is now being developed, the concept of Natural Orifice Surgery (NOS). The existing natural openings of the body started to be used for introduction of surgical instruments for diagnostic purposes and surgical procedures, avoiding penetrating the abdominal wall. Parallel to the American Natural Orifice Surgery Consortium for Assessment and Research (NOSCAR) group, is the New European Surgical Academy (NESA) established in Berlin on June 23, 2006. It is the first European-based NOS working group with participation of scientists and surgeons from different disciplines and countries. After the published experimental achievements had been presented and discussed, the working group decided to concentrate mainly on the transvaginal/transdouglas access in women. Database: A new surgical instrument, the Transdouglas Endoscopic Device (TED) has been designed. This is a flexible multichannel instrument enabling single-entry surgical, urological, and gynecological operations. TED respects the anatomy of the pelvis. To get to the upper abdomen, an S-shaped device was designed, bending first to the front, and then backwards. For the lower abdomen, the U-shaped mode of the instrument was designed. The wide diameter of the device (35 mm) and its multichannel design enables simultaneous use of different instruments, therefore avoiding hybrid procedures. Various surgical and gynecological procedures have been successfully simulated, and the manufacturing of the device is in progress. Preclinical studies will start soon. Conclusions: Transvaginal/transdouglas surgery is expected to be a valid alternative to traditional endoscopic procedures in women. It seems that NOS will create a spectrum of innovative

1. Numerical modeling of ozone production in a pulsed homogeneous discharge: A parameter study

SciTech Connect

Nilsson, J.O.; Eninger, J.E.

1997-02-01

The pulsed volume discharge is an alternative for the efficient generation of ozone in compact systems. This paper presents a parameter study of the reactions in this kind of homogeneous discharge by using a numerical model which solves plasma chemical kinetic rate and energy equations. Results are presented of ozone generation efficiency versus ozone concentration for different parameter combinations. Two parameter regimes are identified and analyzed. In the plasma phase ozone formation regime, where significant amounts of ozone are produced during the discharge pulse, it is found that higher ozone concentrations can be obtained than in the neutral phase ozone formation regime, where most of the ozone is formed after the discharge pulse. In the two-step ozone formation process, the rate of conversion of atomic oxygen plays a key role. In both regimes the ozone generation efficiency increases as n is increased or T{sub 0} decreased. The maximum concentration is 3% at 10 amagat and 100 K. The results on ozone accumulation in multiple pulse discharges are presented. In contrast to the single pulse case, higher efficiency is achieved at lower gas density. This scaling can be explained by losses due to ion currents. A tradeoff can be made between ozone generation efficiency and the number of pulses required to reach a certain concentration.

2. From regional pulse vaccination to global disease eradication: insights from a mathematical model of poliomyelitis.

PubMed

Browne, Cameron J; Smith, Robert J; Bourouiba, Lydia

2015-07-01

Mass-vaccination campaigns are an important strategy in the global fight against poliomyelitis and measles. The large-scale logistics required for these mass immunisation campaigns magnifies the need for research into the effectiveness and optimal deployment of pulse vaccination. In order to better understand this control strategy, we propose a mathematical model accounting for the disease dynamics in connected regions, incorporating seasonality, environmental reservoirs and independent periodic pulse vaccination schedules in each region. The effective reproduction number, Re, is defined and proved to be a global threshold for persistence of the disease. Analytical and numerical calculations show the importance of synchronising the pulse vaccinations in connected regions and the timing of the pulses with respect to the pathogen circulation seasonality. Our results indicate that it may be crucial for mass-vaccination programs, such as national immunisation days, to be synchronised across different regions. In addition, simulations show that a migration imbalance can increase Re and alter how pulse vaccination should be optimally distributed among the patches, similar to results found with constant-rate vaccination. Furthermore, contrary to the case of constant-rate vaccination, the fraction of environmental transmission affects the value of Re when pulse vaccination is present.

3. Architecture and statistical model of a pulse-mode digital multilayer neural network.

PubMed

Kim, Y C; Shanblatt, M A

1995-01-01

A new architecture and a statistical model for a pulse-mode digital multilayer neural network (DMNN) are presented. Algebraic neural operations are replaced by stochastic processes using pseudo-random pulse sequences. Synaptic weights and neuron states are represented as probabilities and estimated as average rates of pulse occurrences in corresponding pulse sequences. A statistical model of error (or noise) is developed to estimate relative accuracy associated with stochastic computing in terms of mean and variance. The stochastic computing technique is implemented with simple logic gates as basic computing elements leading to a high neuron-density on a chip. Furthermore, the use of simple logic gates for neural operations, the pulse-mode signal representation, and the modular design techniques lead to a massively parallel yet compact and flexible network architecture, well suited for VLSI implementation. Any size of a feedforward network can be configured where processing speed is independent of the network size. Multilayer feedforward networks are modeled and applied to pattern classification problems such as encoding and character recognition.

4. Stellar acoustics. I - Adiabatic pulse propagation and modal resonance in polytropic models of bump Cepheids

Whitney, C. A.

1983-11-01

An understanding of the Hertzsprung progression among bump Cepheids is sought in a dualistic viewpoint which combines the idea of propagating pulse echoes with that of modal resonance. Attention is focused on the spherically symmetric pulses that can be regenerated once per cycle if their round trip propagation time equals the period of the overall pulsation. The acoustic properties of polytropic models reveal that the conditions for such reinforcement are likely to be met in models for which the periods of the fundamental and the second overtone pulsation are in the ratio 2:1. Systematic departures from precise resonance may be responsible for the Hertzsprung progression.

5. Dynamical percolation transition in the Ising model studied using a pulsed magnetic field.

PubMed

Biswas, Soumyajyoti; Kundu, Anasuya; Chandra, Anjan Kumar

2011-02-01

We study the dynamical percolation transition of the geometrical clusters in the two-dimensional Ising model when it is subjected to a pulsed field below the critical temperature. The critical exponents are independent of the temperature and pulse width and are different from the (static) percolation transition associated with the thermal transition. For a different model that belongs to the Ising universality class, the exponents are found to be same, confirming that the behavior is a common feature of the Ising class. These observations, along with a universal critical Binder cumulant value, characterize the dynamical percolation of the Ising universality class.

6. Computation of Transverse Injection Into Supersonic Crossflow With Various Injector Orifice Geometries

NASA Technical Reports Server (NTRS)

Foster, Lancert; Engblom, William A.

2003-01-01

Computational results are presented for the performance and flow behavior of various injector geometries employed in transverse injection into a non-reacting Mach 1.2 flow. 3-D Reynolds-Averaged Navier Stokes (RANS) results are obtained for the various injector geometries using the Wind code with the Mentor s Shear Stress Transport turbulence model in both single and multi-species modes. Computed results for the injector mixing, penetration, and induced wall forces are presented. In the case of rectangular injectors, those longer in the direction of the freestream flow are predicted to generate the most mixing and penetration of the injector flow into the primary stream. These injectors are also predicted to provide the largest discharge coefficients and induced wall forces. Minor performance differences are indicated among diamond, circle, and square orifices. Grid sensitivity study results are presented which indicate consistent qualitative trends in the injector performance comparisons with increasing grid fineness.

7. Optimization of Orifice Geometry for Cross-Flow Mixing in a Cylindrical Duct

NASA Technical Reports Server (NTRS)

Sowa, W. A.; Kroll, J. T.; Samuelsen, G. S.; Holdeman, J. D.

1994-01-01

Mixing of gaseous jets in a cross-flow has significant applications in engineering, one example of which is the dilution zone of a gas turbine combustor. Despite years of study, the design of jet injection in combustors is largely based on practical experience. A series of experiments was undertaken to delineate the optimal mixer orifice geometry. A cross-flow to core-flow momentum-flux ratio of 40 and a mass flow ratio of 2.5 were selected as representative of an advanced design. An experimental test matrix was designed around three variables: the number of orifices, the orifice aspect ratio (long-to-short dimension), and the orifice angle. A regression analysis was performed on the data to arrive at an interpolating equation that predicted the mixing performance of orifice geometry combinations within the range of the test matrix parameters. Results indicate that mixture uniformity is a non-linear function of the number of orifices, the orifice aspect ratio, and the orifice angle. Optimum mixing occurs when the asymptotic mean jet trajectories are in the range of 0.35 less than r/R less than 0.5 (where r = 0 is at the mixer wall) at z/R = 1.0. At the optimum number of orifices, the difference between shallow-angled slots with large aspect ratios and round holes is minimal and either approach will lead to good mixing performance. At the optimum number of orifices, it appears possible to have two local optimums where one corresponds to an aspect ratio of 1.0 and the other to a high aspect ratio.

8. Theory and Modeling of Petawatt Laser Pulse Propagation in Low Density Plasmas

SciTech Connect

2016-12-08

Report describing accomplishments in all-optical control of self-injection in laser-plasma accelerators and in developing advanced numerical models of laser-plasma interactions. All-optical approaches to controlling electron self-injection and beam formation in laser-plasma accelerators (LPAs) were explored. It was demonstrated that control over the laser pulse evolution is the key ingredient in the generation of low-background, low-phase-space-volume electron beams. To this end, preserving a smooth laser pulse envelope throughout the acceleration process can be achieved through tuning the phase and amplitude of the incident pulse. A negative frequency chirp compensates the frequency red- shift accumulated due to wake excitation, preventing evolution of the pulse into a relativistic optical shock. This reduces the ponderomotive force exerted on quiescent plasma electrons, suppressing expansion of the bubble and continuous injection of background electrons, thereby reducing the charge in the low-energy tail by an order of magnitude. Slowly raising the density in the pulse propagation direction locks electrons in the accelerating phase, boosting their energy, keeping continuous injection at a low level, tripling the brightness of the quasi-monoenergetic component. Additionally, propagating the negatively chirped pulse in a plasma channel suppresses diffraction of the pulse leading edge, further reducing continuous injection. As a side effect, oscillations of the pulse tail may be enhanced, leading to production of low-background, polychromatic electron beams. Such beams, consisting of quasi-monoenergetic components with controllable energy and energy separation, may be useful as drivers of polychromatic x-rays based on Thomson backscattering. These all-optical methods of electron beam quality control are critically important for the development of future compact, high-repetition-rate, GeV-scale LPA using 10 TW-class, ultra-high bandwidth pulses and mm-scale, dense

9. Scintillation event energy measurement via a pulse model based iterative deconvolution method

Deng, Zhenzhou; Xie, Qingguo; Duan, Zhiwen; Xiao, Peng

2013-11-01

This work focuses on event energy measurement, a crucial task of scintillation detection systems. We modeled the scintillation detector as a linear system and treated the energy measurement as a deconvolution problem. We proposed a pulse model based iterative deconvolution (PMID) method, which can process pileup events without detection and is adaptive for different signal pulse shapes. The proposed method was compared with digital gated integrator (DGI) and digital delay-line clipping (DDLC) using real world experimental data. For singles data, the energy resolution (ER) produced by PMID matched that of DGI. For pileups, the PMID method outperformed both DGI and DDLC in ER and counts recovery. The encouraging results suggest that the PMID method has great potentials in applications like photon-counting systems and pulse height spectrometers, in which multiple-event pileups are common.

10. INTERACTION OF LASER RADIATION WITH MATTER: Laser swelling model for polymers irradiated by nanosecond pulses

Malyshev, A. Yu; Bityurin, N. M.

2005-09-01

Mechanisms of laser swelling of polymers are considered. A theoretical model for one of such mechanisms is constructed and investigated. This mechanism is based on the formation of a thermoelastic wave upon absorption of a laser pulse. Tensile stresses in this wave lead to elastic and plastic deformation of a polymer in the heated region and to the formation of convex structures (humps). The threshold energy density of a laser pulse required for the production of a residual hump under laser irradiation is obtained analytically. A formula for the height of this hump is also derived. The model explains the earlier experimental data from the literature on swelling of a PMMA film irradiated by UV pulses.

11. Analysis of an SIR Epidemic Model with Pulse Vaccination and Distributed Time Delay

PubMed Central

Gao, Shujing; Teng, Zhidong; Nieto, Juan J.; Torres, Angela

2007-01-01

Pulse vaccination, the repeated application of vaccine over a defined age range, is gaining prominence as an effective strategy for the elimination of infectious diseases. An SIR epidemic model with pulse vaccination and distributed time delay is proposed in this paper. Using the discrete dynamical system determined by the stroboscopic map, we obtain the exact infection-free periodic solution of the impulsive epidemic system and prove that the infection-free periodic solution is globally attractive if the vaccination rate is larger enough. Moreover, we show that the disease is uniformly persistent if the vaccination rate is less than some critical value. The permanence of the model is investigated analytically. Our results indicate that a large pulse vaccination rate is sufficient for the eradication of the disease. PMID:18322563

12. MODELING NANOCRYSTALLINE GRAIN GROWTH DURING THE PULSED ELECTRODEPOSITION OF GOLD-COPPER

SciTech Connect

Jankowski, A F

2005-10-27

The process parameters of current density, pulse duration, and cell potential affect both the structure and composition of electrodeposits. The mechanism for nucleation and growth as determined from current transients yield relationships for nucleus density and nucleation rate. To develop an understanding of the role of the process parameters on grain size, as a design structural parameter to control strength for example, a formulation is presented to model the affects of the deposition energy on grain size and morphology. An activation energy for the deposition process is modeled that reveals different growth mechanisms, wherein nucleation and diffusion effects are each dominant as dependent upon pulse duration. A diffusion coefficient common for each of the pulsed growth modes demarcates an observed transition in growth from smooth to rough surfaces.

13. Modeling the Pulse Line Ion Accelerator (PLIA): an algorithm for quasi-static field solution.

SciTech Connect

Friedman, A; Briggs, R J; Grote, D P; Henestroza, E; Waldron, W L

2007-06-18

The Pulse-Line Ion Accelerator (PLIA) is a helical distributed transmission line. A rising pulse applied to the upstream end appears as a moving spatial voltage ramp, on which an ion pulse can be accelerated. This is a promising approach to acceleration and longitudinal compression of an ion beam at high line charge density. In most of the studies carried out to date, using both a simple code for longitudinal beam dynamics and the Warp PIC code, a circuit model for the wave behavior was employed; in Warp, the helix I and V are source terms in elliptic equations for E and B. However, it appears possible to obtain improved fidelity using a ''sheath helix'' model in the quasi-static limit. Here we describe an algorithmic approach that may be used to effect such a solution.

14. Comparison of pulsed corona plasma and pulsed electric fields for the decontamination of water containing Legionella pneumophila as model organism.

PubMed

Banaschik, Robert; Burchhardt, Gerhard; Zocher, Katja; Hammerschmidt, Sven; Kolb, Juergen F; Weltmann, Klaus-Dieter

2016-12-01

Pulsed corona plasma and pulsed electric fields were assessed for their capacity to kill Legionella pneumophila in water. Electrical parameters such as in particular dissipated energy were equal for both treatments. This was accomplished by changing the polarity of the applied high voltage pulses in a coaxial electrode geometry resulting in the generation of corona plasma or an electric field. For corona plasma, generated by high voltage pulses with peak voltages of +80kV, Legionella were completely killed, corresponding to a log-reduction of 5.4 (CFU/ml) after a treatment time of 12.5min. For the application of pulsed electric fields from peak voltages of -80kV a survival of log 2.54 (CFU/ml) was still detectable after this treatment time. Scanning electron microscopy images of L. pneumophila showed rupture of cells after plasma treatment. In contrast, the morphology of bacteria seems to be intact after application of pulsed electric fields. The more efficient killing for the same energy input observed for pulsed corona plasma is likely due to induced chemical processes and the generation of reactive species as indicated by the evolution of hydrogen peroxide. This suggests that the higher efficacy and efficiency of pulsed corona plasma is primarily associated with the combined effect of the applied electric fields and the promoted reaction chemistry.

15. Femtosecond pulse laser ablation of chromium: experimental results and two-temperature model simulations

Saghebfar, M.; Tehrani, M. K.; Darbani, S. M. R.; Majd, A. E.

2017-01-01

In this work, the results of experimental and computational single- and multi-shot ablation threshold and the incubation effect of chromium metal sample, irradiated by ultrashort laser pulses, are presented. The experimental value of the ablation threshold is determined based on D2 method by measuring the outer ablation crater diameters as a function of incident laser pulse energy using 800 nm, 30 fs, laser pulses. The value of 0.19 ± 0.04 (J/cm2 ), is obtained for the single-shot ablation threshold fluence. The experimental results are compared with time-dependent heat flow calculations based on the two-temperature model and the effect of number and separation time of two consecutive laser pulses with the same total fluence is studied for the Cr target. Moreover, the role of pulse width and absorbed fluence in thermal equilibrium time between electrons and lattice is investigated in two-temperature model. The thermal equilibrium between electron and lattice is established after a few picoseconds for low fluences and after a few tens of picoseconds at higher fluences.

16. Prospects for measuring neutron-star masses and radii with X-ray pulse profile modeling

SciTech Connect

Psaltis, Dimitrios; Özel, Feryal; Chakrabarty, Deepto E-mail: fozel@email.arizona.edu

2014-06-01

Modeling the amplitudes and shapes of the X-ray pulsations observed from hot, rotating neutron stars provides a direct method for measuring neutron-star properties. This technique constitutes an important part of the science case for the forthcoming NICER and proposed LOFT X-ray missions. In this paper, we determine the number of distinct observables that can be derived from pulse profile modeling and show that using only bolometric pulse profiles is insufficient for breaking the degeneracy between inferred neutron-star radius and mass. However, we also show that for moderately spinning (300-800 Hz) neutron stars, analysis of pulse profiles in two different energy bands provides additional constraints that allow a unique determination of the neutron-star properties. Using the fractional amplitudes of the fundamental and the second harmonic of the pulse profile in addition to the amplitude and phase difference of the spectral color oscillations, we quantify the signal-to-noise ratio necessary to achieve a specified measurement precision for neutron star radius. We find that accumulating 10{sup 6} counts in a pulse profile is sufficient to achieve a ≲ 5% uncertainty in the neutron star radius, which is the level of accuracy required to determine the equation of state of neutron-star matter. Finally, we formally derive the background limits that can be tolerated in the measurements of the various pulsation amplitudes as a function of the system parameters.

17. A time-dependent model of pulse-driven radio frequency capacitively coupled collisional plasma sheath

Rahman, M. T.; Hossain, M. Mofazzal

2017-01-01

The time-dependent model of ion motion is used to propose an analytical model for dual frequency (DF) capacitively coupled plasma (CCP) sheath driven by a pulsed source and a radio-frequency source. In this model, the sheath is considered to be collisional. In this model, the time dependent terms of ion fluid equations are ignored, but the electric field, ion motion and ion density remain time dependent. Electron profile is assumed to be step-like. Analytical expressions for electron sheath width and sheath potential have been developed. The calculated sheath width and potential are compared with the dual radio frequency driven time dependent models of capacitively coupled plasma sheath. From the temporal evaluation of sheath motion and potential, it has been found that pulse driven sheath has higher sheath potential and sheath width than that of conventional radio frequency driven DF CCP. Moreover, it is also found that ion energy spread can be reduced using pulsed power. From the temporal investigation of sheath motion and potential, it has been found that the duty cycle of the pulse power significantly affects sheath width and sheath potential.

18. Choked-Flow Inlet Orifice Bubbler for Creating Small Bubbles in Mercury

SciTech Connect

Wendel, Mark W; Abdou, Ashraf A; Riemer, Bernie

2013-01-01

Pressure waves created in liquid mercury pulsed spallation targets like the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory, induce cavitation damage on the target container. The cavitation damage is thought to limit the lifetime of the target for power levels at and above 1 MW. One way to mitigate the damage would be to absorb the pressure pulse energy into a dispersed population of small bubbles, however, creating a bubble size distribution that is sufficiently large and disperse in mercury is challenging due to the high surface tension. Also, measuring the population is complicated by the opacity and the high level of turbulent mixing. Recent advances in bubble diagnostics by batch sampling the mercury made it possible to compare bubble populations for different techniques in a SNS-1/20th scale test loop. More than 10 bubblers were tested and the most productive bubblers were taken for in-beam testing at the Los Alamos Neutron Science Center (LANSCE) WNR user facility. One bubbler design, referred to as the inlet-orifice bubbler, that showed moderate success in creating populations also has an added advantage that it could easily be included in the existing SNS full-scale mercury target configuration. Improvements to the bubbler were planned including a reduction of the nozzle size to choke the gas injection, thus steadying the injected mass flow and allowing multiple nozzles to work off of a common plenum. For the first time, reliable bubble population data are available in the prototypical target geometry and can be compared with populations that mitigated cavitation damage. This paper presents those experimental results.

19. [Design and implementation of the pulse wave generator with field programmable gate array based on windkessel model].

PubMed

Wang, Hao; Fu, Quanhai; Xu, Lisheng; Liu, Jia; He, Dianning; Li, Qingchun

2014-10-01

Pulse waves contain rich physiological and pathological information of the human vascular system. The pulse wave diagnosis systems are very helpful for the clinical diagnosis and treatment of cardiovascular diseases. Accurate pulse waveform is necessary to evaluate the performances of the pulse wave equipment. However, it is difficult to obtain accurate pulse waveform due to several kinds of physiological and pathological conditions for testing and maintaining the pulse wave acquisition devices. A pulse wave generator was designed and implemented in the present study for this application. The blood flow in the vessel was simulated by modeling the cardiovascular system with windkessel model. Pulse waves can be generated based on the vascular systems with four kinds of resistance. Some functional models such as setting up noise types and signal noise ratio (SNR) values were also added in the designed generator. With the need of portability, high speed dynamic response, scalability and low power consumption for the system, field programmable gate array (FPGA) was chosen as hardware platform, and almost all the works, such as developing an algorithm for pulse waveform and interfacing with memory and liquid crystal display (LCD), were implemented under the flow of system on a programmable chip (SOPC) development. When users input in the key parameters through LCD and touch screen, the corresponding pulse wave will be displayed on the LCD and the desired pulse waveform can be accessed from the analog output channel as well. The structure of the designed pulse wave generator is simple and it can provide accurate solutions for studying and teaching pulse waves and the detection of the equipments for acquisition and diagnosis of pulse wave.

20. Pulse method of structural and parametric identification of models of heterogeneous catalytic processes

SciTech Connect

Kafarov, V.V.; Pisarenko, V.N.; Usacheva, I.I.

1986-04-01

A description is given of a pulse method for the investigation of heterogeneous catalytic processes, through which the parameters of a model can be evaluated with high accuracy. An example is given of the application of the procedure to an alloy catalyst.

1. Universal pulse shape scaling function and exponents: critical test for avalanche models applied to Barkhausen noise.

PubMed

Mehta, Amit P; Mills, Andrea C; Dahmen, Karin A; Sethna, James P

2002-04-01

In order to test if the universal aspects of Barkhausen noise in magnetic materials can be predicted from recent variants of the nonequilibrium zero-temperature Random Field Ising Model, we perform a quantitative study of the universal scaling function derived from the Barkhausen pulse shape in simulations and experiment. Through data collapses and scaling relations we determine the critical exponents tau and 1/sigma nu z in both simulation and experiment. Although we find agreement in the critical exponents, we find differences between theoretical and experimental pulse shape scaling functions as well as between different experiments.

2. Analytical model for interaction of short intense laser pulse with solid target

SciTech Connect

Luan, S. X.; Ma, G. J.; Yu, Wei; Yu, M. Y.; Zhang, Q. J.; Sheng, Z. M.; Murakami, M.

2011-04-15

A simple but comprehensive two-dimensional analytical model for the interaction of a normally incident short intense laser pulse with a solid-density plasma is proposed. Electron cavitation near the target surface by the laser ponderomotive force induces a strong local electrostatic charge-separation field. The cavitation makes possible mode conversion of the laser light into longitudinal electron oscillation at laser frequency, even for initial normal incidence of laser pulse. The intense charge-separation field in the cavity can significantly enhance the laser induced uxB electron oscillation at twice laser frequency to density levels even higher than that of the initial target.

3. On the intermittent route to resonance for flow through an orifice in a duct

Kamin, Manu; Mathew, Joseph

2016-11-01

In experiments done by Vineeth et al. (2015) on flow in a duct-orifice arrangement, flow enters through the duct inlet, and leaves into the atmosphere through the orifice exit, "whistling" was observed at a Reynolds number of 4200, where large amplitude pressure oscillations were observed. At slightly lower Reynolds numbers, bursts of smaller amplitudes of pressure oscillations were observed to appear intermittently. For a similar configuration, LES were carried out. Both whistling and intermittency were observed in the simulations. As air flows from the duct into the orifice, it turns sharply around the corner at the duct-orifice interface, and hence, flow separation occurs, and a shear layer is formed at the mouth of the orifice. The mechanism of whistling was found to be the shear layer within the orifice flapping about and hitting the trailing edge of the orifice periodically, thus causing the shear layer to break and roll up into a vortex. Hurst exponent was measured in the time series data obtained. It was found to gradually drop to zero as the flow approached the state of whistling, since the growth rates of all the long term and short term trends in the time series vanish. A loss of multifractality in the time series was also observed as flow approached whistling. Research Scholar (MSc. Engg.), Aerospace Engineering Dept., Indian Institute of Science.

4. Nanosecond laser pulse stimulation of spiral ganglion neurons and model cells

PubMed Central

Rettenmaier, Alexander; Lenarz, Thomas; Reuter, Günter

2014-01-01

Optical stimulation of the inner ear has recently attracted attention, suggesting a higher frequency resolution compared to electrical cochlear implants due to its high spatial stimulation selectivity. Although the feasibility of the effect is shown in multiple in vivo experiments, the stimulation mechanism remains open to discussion. Here we investigate in single-cell measurements the reaction of spiral ganglion neurons and model cells to irradiation with a nanosecond-pulsed laser beam over a broad wavelength range from 420 nm up to 1950 nm using the patch clamp technique. Cell reactions were wavelength- and pulse-energy-dependent but too small to elicit action potentials in the investigated spiral ganglion neurons. As the applied radiant exposure was much higher than the reported threshold for in vivo experiments in the same laser regime, we conclude that in a stimulation paradigm with nanosecond-pulses, direct neuronal stimulation is not the main cause of optical cochlea stimulation. PMID:24761285

5. Investigation of interaction femtosecond laser pulses with skin and eyes mathematical model

Rogov, P. U.; Smirnov, S. V.; Semenova, V. A.; Melnik, M. V.; Bespalov, V. G.

2016-08-01

We present a mathematical model of linear and nonlinear processes that takes place under the action of femtosecond laser radiation on the cutaneous covering. The study is carried out and the analytical solution of the set of equations describing the dynamics of the electron and atomic subsystems and investigated the processes of linear and nonlinear interaction of femtosecond laser pulses in the vitreous of the human eye, revealed the dependence of the pulse duration on the retina of the duration of the input pulse and found the value of the radiation power density, in which there is a self-focusing is obtained. The results of the work can be used to determine the maximum acceptable energy, generated by femtosecond laser systems, and to develop Russian laser safety standards for femtosecond laser systems.

6. Investigation on stresses of superconductors under pulsed magnetic fields based on multiphysics model

Yang, Xiaobin; Li, Xiuhong; He, Yafeng; Wang, Xiaojun; Xu, Bo

2017-04-01

A multiphysics model for the numerical computation of stresses, trapped field and temperature distribution of a infinite long superconducting cylinder is proposed, based on which the stresses, including the thermal stresses and mechanical stresses due to Lorentz force, and trapped fields in the superconductor subjected to pulsed magnetic fields are analyzed. By comparing the results under pulsed magnetic fields with different pulse durations, it is found that the both the mechanical stress due to the electromagnetic force and the thermal stress due to temperature gradient contribute to the total stress level in the superconductor. For pulsed magnetic field with short durations, the thermal stress is the dominant contribution to the total stress, because the heat generated by AC-loss builds up significant temperature gradient in such short durations. However, for a pulsed field with a long duration the gradient of temperature and flux, as well as the maximal tensile stress, are much smaller. And the results of this paper is meaningful for the design and manufacture of superconducting permanent magnets.

7. Perturbative transport modeling and comparison to cold-pulse and heat-pulse propagation experiments in Alcator C-Mod and DIII-D

Rodriguez Fernandez, P.; White, A. E.; Cao, N. M.; Creely, A. J.; Greenwald, M. J.; Howard, N. T.; Hubbard, A. E.; Hughes, J. W.; Irby, J. H.; Petty, C. C.; Rice, J. E.; Alcator C-Mod Team

2016-10-01

Possible ``non-local'' transport phenomena are often observed in tokamak plasmas. Different models have been proposed to explain fast responses during perturbative transport experiments, including non-diffusive effects. Specific tools to characterize the dynamic behavior and power balance analysis using TRANSP and the quasi-linear trapped gyro-landau fluid code TGLF have been developed to analyze Alcator C-Mod experiments. Recent results from cold pulse experiments show that fast core temperature increases following edge cold-pulse injections (peak within 10ms , while τE 25ms) are not correlated with the direction of intrinsic rotation, and instead the amplitude of the core response depends on density, plasma current and RF input power. The propagation of the cold pulse can be compared with propagation of heat pulses from sawteeth, and both may be used to probe changes in temperature profile stiffness. A Laser Blow Off (LBO) system is being developed for DIII-D that will allow further validation and cross-machine comparison of cold pulse experiments. LBO at DIII-D will also allow for direct comparisons with ECH perturbative heat pulse experiments. Work supported by US DOE under Grants DE-FC02-99ER54512 (C-Mod) and DE-FC02-04ER54698 (DIII-D) and La Caixa Fellowship.

8. Scale Modeling for the PATRIOT Electromagnetic Pulse Test.

DTIC Science & Technology

1981-05-01

modeling is possible in general is due to the linearity of Maxwell’s equations that deseribo th’ fields in any electromagnetic system. It is necessary... equations are valid for nonhomogeneous as well as homogeneous media. Sinclair shows that "for an arbitrary choice of the tour scale factors p. a, , and y it...linear dimension) scale factor, a= scale factor for electric field intensity, = scale factor for magnetic ield intencity , = scale factor for time

9. Thermal modeling for pulsed radiofrequency ablation: analytical study based on hyperbolic heat conduction.

PubMed

López Molina, Juan A; Rivera, María J; Trujillo, Macarena; Berjano, Enrique J

2009-04-01

The objectives of this study were to model the temperature progress of a pulsed radiofrequency (RF) power during RF heating of biological tissue, and to employ the hyperbolic heat transfer equation (HHTE), which takes the thermal wave behavior into account, and compare the results to those obtained using the heat transfer equation based on Fourier theory (FHTE). A theoretical model was built based on an active spherical electrode completely embedded in the biological tissue, after which HHTE and FHTE were analytically solved. We found three typical waveforms for the temperature progress depending on the relations between the dimensionless duration of the RF pulse delta(a) and the expression square root of lambda(rho-1), with lambda as the dimensionless thermal relaxation time of the tissue and rho as the dimensionless position. In the case of a unique RF pulse, the temperature at any location was the result of the overlapping of two different heat sources delayed for a duration delta(a) (each heat source being produced by a RF pulse of limitless duration). The most remarkable feature in the HHTE analytical solution was the presence of temperature peaks traveling through the medium at a finite speed. These peaks not only occurred during the RF power switch-on period but also during switch off. Finally, a physical explanation for these temperature peaks is proposed based on the interaction of forward and reverse thermal waves. All-purpose analytical solutions for FHTE and HHTE were obtained during pulsed RF heating of biological tissues, which could be used for any value of pulsing frequency and duty cycle.

10. The Design of Control Pulses for Heisenberg Always-On Qubit Models

Magyar, Rudolph

2015-03-01

One model for a universal quantum computer is a spin array with constant nearest neighbor interactions and a controlled unidirectional site-specific magnetic field to generate unitary transformations. This system can be described by a Heisenberg spin Hamiltonian and can be simulated for on the order of 50 spins. It has recently been shown that time-dependent density functional inspired methods may be used to relate various spin models of qubits to ones that may be easier to compute numerically allowing potentially the efficient simulation of greater numbers of spins. One of the challenges of such an agenda is the identification of control pulses that produce desired gate operations (CNOT and single qubit phase gates). We apply control theory to design a universal set of pulses for a Heisenberg always-on model Hamiltonian for a few qubits and compare to known pulses when available. We suggest how this approach may be useful to design control pulses in other realistic designs. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Security Administration under contract DE-AC04-94AL85000.

11. Simulink based behavioural modelling of a pulse oximeter for deployment in rapid development, prototyping and verification.

PubMed

Shokouhian, M; Morling, R C S; Kale, I

2012-01-01

The pulse oximeter is a well-known device for measuring the level of oxygen in blood. Since their invention, pulse oximeters have been under constant development in both aspects of hardware and software; however there are still unsolved problems that limit their performance [6], [7]. Many fresh algorithms and new design techniques are being suggested every year by industry and academic researchers which claim that they can improve accuracy of measurements [8], [9]. With the lack of an accurate computer-based behavioural model for pulse oximeters, the only way for evaluation of these newly developed systems and algorithms is through hardware implementation which can be both expensive and time consuming. This paper presents an accurate Simulink based behavioural model for a pulse oximeter that can be used by industry and academia alike working in this area, as an exploration as well as productivity enhancement tool during their research and development process. The aim of this paper is to introduce a new computer-based behavioural model which provides a simulation environment from which new ideas can be rapidly evaluated long before the real implementation.

12. Two-photon finite-pulse model for resonant transitions in attosecond experiments

Jiménez-Galán, Álvaro; Martín, Fernando; Argenti, Luca

2016-02-01

We present an analytical model capable of describing two-photon ionization of atoms with attosecond pulses in the presence of intermediate and final isolated autoionizing states. The model is based on the finite-pulse formulation of second-order time-dependent perturbation theory. It approximates the intermediate and final states with Fano's theory for resonant continua, and it depends on a small set of atomic parameters that can either be obtained from separate ab initio calculations or be extracted from a few selected experiments. We use the model to compute the two-photon resonant photoelectron spectrum of helium below the N =2 threshold for the RABITT (reconstruction of attosecond beating by interference of two-photon transitions) pump-probe scheme, in which an XUV attosecond pulse train is used in association with a weak IR probe, obtaining results in quantitative agreement with those from accurate ab initio simulations. In particular, we show that (i) the use of finite pulses results in a homogeneous redshift of the RABITT beating frequency, as well as a resonant modulation of the beating frequency in proximity to intermediate autoionizing states; (ii) the phase of resonant two-photon amplitudes generally experiences a continuous excursion as a function of the intermediate detuning, with either zero or 2 π overall variation.

13. MODELING MULTI-WAVELENGTH PULSE PROFILES OF THE MILLISECOND PULSAR PSR B1821–24

SciTech Connect

Du, Yuanjie; Shuai, Ping; Bei, Xiaomin; Chen, Shaolong; Fu, Linzhong; Huang, Liangwei; Lin, Qingqing; Meng, Jing; Wu, Yaojun; Zhang, Hengbin; Zhang, Qian; Zhang, Xinyuan; Qiao, Guojun

2015-03-10

PSR B1821–24 is a solitary millisecond pulsar that radiates multi-wavelength pulsed photons. It has complex radio, X-ray, and γ-ray pulse profiles with distinct peak phase separations that challenge the traditional caustic emission models. Using the single-pole annular gap model with a suitable magnetic inclination angle (α = 40°) and viewing angle (ζ = 75°), we managed to reproduce its pulse profiles of three wavebands. It is found that the middle radio peak originated from the core gap region at high altitudes, and the other two radio peaks originated from the annular gap region at relatively low altitudes. Two peaks of both X-ray and γ-ray wavebands basically originated from the annular gap region, while the γ-ray emission generated from the core gap region contributes somewhat to the first γ-ray peak. Precisely reproducing the multi-wavelength pulse profiles of PSR B1821–24 enables us to understand emission regions of distinct wavebands and justify pulsar emission models.

14. Numerical modeling of the intracavity stimulated Raman scattering as a source of subnanosecond optical pulses

Yashkir, Yuri M.; Yashkir, Yuriy Y.

2004-09-01

We present a computer numerical model (virtual sub-nanosecond laser) utilizing intracavity stimulated Raman scattering. The goal of this work is to shorten laser output pulses (for which the highly nonlinear frequency conversion process stimulated Raman scattering is used) and to obtain high efficiency (which is enhanced by placing a Raman-active crystal inside the cavity where the fundamental laser frequency intensity is maximal). The following laser components were modeled: a diodepumped solidstate laser active medium (a crystal of the Nd3+:YLF type), a closed cavity for a wave on its fundamental frequency with a Q-switching element and an internal subcavity with a Ramanactive crystal with controlled output coupler transmission at the Raman frequency. The model components are: a numerical integrator of a set of three rate equations (for an inverse population of the laser medium and for the number of fundamental and Stokes frequency photons), random number sources for radiation seeding, and an interactive data input interface and graphic output. A wide range of parameters was investigated and output pulses as short as 0.8 ns were found. The optimal conditions for the maximal peak power of Stokes pulses were determined and the conditions for generating pulse trains for burst laser machining were identified.

15. Velocity field near the jet orifice of a round jet in a crossflow

NASA Technical Reports Server (NTRS)

Fearn, R. L.; Benson, J. P.

1979-01-01

Experimentally determined velocities at selected locations near the jet orifice are presented and analyzed for a round jet in crossflow. Jet-to-crossflow velocity ratios of four and eight were studied experimentally for a round subsonic jet of air exhausting perpendicularly through a flat plate into a subsonic crosswind of the same temperature. Velocity measurements were made in cross sections to the jet plume located from one to four jet diameters from the orifice. Jet centerline and vortex properties are presented and utilized to extend the results of a previous study into the region close to the jet orifice.

16. Boundary layer separation and vortex creation in superflow through small orifices

SciTech Connect

Stone, M.; Srivastava, A.M.

1996-03-01

The authors report numerical solutions of the Gross-Pitaevskii equation for two dimensional flow is a superfluid condensate through a small orifice. When the superfluid velocity in the center of the orifice exceeds about 60% of the speed of sound, the flow in the throat of the orifice becomes unstable to a form of boundary layer separation. Low condensate-density regions bulge away from the walls and form the cores of singly quantized vortices. These detach from the boundary and are convected downstream.

17. Hydrodynamic model for ultra-short pulse ablation of hard dental tissue

SciTech Connect

London, R.A.; Bailey, D.S.; Young, D.A.; Alley, W.E.; Feit, M.D.; Rubenchik, A.M.; Neev, J.

1996-02-29

A computational model for the ablation of tooth enamel by ultra-short laser pulses is presented. The role of simulations using this model in designing and understanding laser drilling systems is discussed. Pulses of duration 300 fsec and intensity greater than 10{sup 12} W/cm{sup 2} are considered. Laser absorption proceeds via multi-photon initiated plasma mechanism. The hydrodynamic response is calculated with a finite difference method, using an equation of state constructed from thermodynamic functions including electronic, ion motion, and chemical binding terms. Results for the ablation efficiency are presented. An analytic model describing the ablation threshold and ablation depth is presented. Thermal coupling to the remaining tissue and long-time thermal conduction are calculated. Simulation results are compared to experimental measurements of the ablation efficiency. Desired improvements in the model are presented.

18. Pulse-transmission Oscillators: Autonomous Boolean Models and the Yeast Cell Cycle

Sevim, Volkan; Gong, Xinwei; Socolar, Joshua

2010-03-01

Models of oscillatory gene expression typically involve a constitutively expressed or positively autoregulated gene which is repressed by a negative feedback loop. In Boolean representations of such systems, which include the repressilator and relaxation oscillators, dynamical stability stems from the impossibility of satisfying all of the Boolean rules at once. We consider a different class of networks, in which oscillations are due to the transmission of a pulse of gene activation around a ring. Using autonomous Boolean modeling methods, we show how the circulating pulse can be stabilized by decoration of the ring with certain feedback and feed-forward motifs. We then discuss the relation of these models to ODE models of transcriptional networks, emphasizing the role of explicit time delays. Finally, we show that a network recently proposed as a generator of cell cycle oscillations in yeast contains the motifs required to support stable transmission oscillations.

19. Thermal Modeling for Pulsed Inductive FRC Plasmoid Thrusters

Pfaff, Michael

Due to the rising importance of space based infrastructure, long-range robotic space missions, and the need for active attitude control for spacecraft, research into Electric Propulsion is becoming increasingly important. Electric Propulsion (EP) systems utilize electric power to accelerate ions in order to produce thrust. Unlike traditional chemical propulsion, this means that thrust levels are relatively low. The trade-off is that EP thrusters have very high specific impulses (Isp), and can therefore make do with far less onboard propellant than cold gas, monopropellant, or bipropellant engines. As a consequence of the high power levels used to accelerate the ionized propellant, there is a mass and cost penalty in terms of solar panels and a power processing unit. Due to the large power consumption (and waste heat) from electric propulsion thrusters, accurate measurements and predictions of thermal losses are needed. Excessive heating in sensitive locations within a thruster may lead to premature failure of vital components. Between the fixed cost required to purchase these components, as well as the man-hours needed to assemble (or replace) them, attempting to build a high-power thruster without reliable thermal modeling can be expensive. This paper will explain the usage of FEM modeling and experimental tests in characterizing the ElectroMagnetic Plasmoid Thruster (EMPT) and the Electrodeless Lorentz Force (ELF) thruster at the MSNW LLC facility in Redmond, Washington. The EMPT thruster model is validated using an experimental setup, and steady state temperatures are predicted for vacuum conditions. Preliminary analysis of the ELF thruster indicates possible material failure in absence of an active cooling system for driving electronics and for certain power levels.

20. First model of the shielded pulsed superconducting energy storage

SciTech Connect

Shintomi, T.; Masuda, M.; Eyssa, Y.M.; Boom, R.W.

1981-09-01

The model was designed and constructed to test the effectiveness, the construction problems, and the scaling problems. The stored energy is 200 kJ, and its available energy is designed as 50 kJ at the transfer time less than 50 ms. The shield coil is distributed around the superconductive coil in a simple form for easy construction. The measurement of the leakage field showed that the simplified distribution of the shield coil was available. The dewar was constructed to have a wall as thin as possible with small heat leak by using GFRP supports. The design value of heat leak agreed with measurement. 4 refs.

1. Improved volume-averaged model for steady and pulsed-power electronegative discharges

SciTech Connect

Kim, Sungjin; Lieberman, M. A.; Lichtenberg, A. J.; Gudmundsson, J. T.

2006-11-15

An improved volume-averaged global model is developed for a cylindrical (radius R, length L) electronegative (EN) plasma that is applicable over a wide range of electron densities, electronegativities, and pressures. It is applied to steady and pulsed-power oxygen discharges. The model incorporates effective volume and surface loss factors for positive ions, negative ions, and electrons combining three electronegative discharge regimes: a two-region regime with a parabolic EN core surrounded by an electropositive edge, a one-region parabolic EN plasma, and a one-region flat-topped EN plasma, spanning the plasma parameters and gas pressures of interest for low pressure processing (below a few hundred millitorr). Pressure-dependent effective volume and surface loss factors are also used for the neutral species. A set of reaction rate coefficients, updated from previous model calculations, is developed for oxygen for the species O{sub 2}, O{sub 2}({sup 1}{delta}{sub g}), O, O{sub 2}{sup +}, O{sup +}, and O{sup -}, based on the latest published cross-section sets and measurements. The model solutions yield all of the quantities above together with such important processing quantities such as the neutral/ion flux ratio {gamma}{sub O}/{gamma}{sub i}, with the discharge aspect ratio 2R/L and pulsed-power period and duty ratio (pulse on-time/pulse period) as parameters. The steady discharge results are compared to an experiment, giving good agreement. For steady discharges, increasing 2R/L from 1 to 6 leads to a factor of 0.45 reduction in {gamma}{sub O}/{gamma}{sub i}. For pulsed discharges with a fixed duty ratio, {gamma}{sub O}/{gamma}{sub i} is found to have a minimum with respect to pulse period. A 25% duty ratio pulse reduces {gamma}{sub O}/{gamma}{sub i} by a factor of 0.75 compared to the steady-state case.

2. Computational modeling of pulsed-power-driven magnetized target fusion experiments

SciTech Connect

Sheehey, P.; Kirkpatrick, R.; Lindemuth, I.

1995-08-01

Direct magnetic drive using electrical pulsed power has been considered impractically slow for traditional inertial confinement implosion of fusion targets. However, if the target contains a preheated, magnetized plasma, magnetothermal insulation may allow the near-adiabatic compression of such a target to fusion conditions on a much slower time scale. 100-MJ-class explosive flux compression generators with implosion kinetic energies far beyond those available with conventional fusion drivers, are an inexpensive means to investigate such magnetized target fusion (MTF) systems. One means of obtaining the preheated and magnetized plasma required for an MTF system is the recently reported {open_quotes}MAGO{close_quotes} concept. MAGO is a unique, explosive-pulsed-power driven discharge in two cylindrical chambers joined by an annular nozzle. Joint Russian-American MAGO experiments have reported D-T neutron yields in excess of 10{sup 13} from this plasma preparation stage alone, without going on to the proposed separately driven NM implosion of the main plasma chamber. Two-dimensional MED computational modeling of MAGO discharges shows good agreement to experiment. The calculations suggest that after the observed neutron pulse, a diffuse Z-pinch plasma with temperature in excess of 100 eV is created, which may be suitable for subsequent MTF implosion, in a heavy liner magnetically driven by explosive pulsed power. Other MTF concepts, such as fiber-initiated Z-pinch target plasmas, are also being computationally and theoretically evaluated. The status of our modeling efforts will be reported.

3. A mathematical model of pulse-coded hormone signal responses in pituitary gonadotroph cells

PubMed Central

Magill, John C.; Ciccone, Nick A.; Kaiser, Ursula B.

2014-01-01

Cells in the pituitary that synthesize luteinizing and follicle-stimulating hormones regulate the relative production of these two key reproductive hormones in response to signals from the hypothalamus. These signals are encoded in the frequency of gonadotrophin-releasing-hormone pulses. In vitro experiments with a murine-derived cell line have identified key elements of the processes that decode the signal to regulate transcription of the subunits encoding these hormones. The mathematical model described in this paper is based on the results of those experiments and advances quantitative understanding of the biochemical decoder. The model consists of non-linear differential equations for each of six processes that lead to the synthesis of follicle-stimulating hormone. Simulations of the model exhibit key characteristics found in the experiments, including a preference for follicle-stimulating hormone synthesis at low pulse frequencies and a loss of this characteristic when a mutation is introduced. PMID:24095971

4. Effect of the Reversal of Air Flow upon the Discharge Coefficient of Durley Orifices

NASA Technical Reports Server (NTRS)

Ware, Marsden

1921-01-01

Experiments were conducted to obtain information on the relationship between the coefficients for flow in two directions through thin plate orifices at low velocities. The results indicate that the ratio of the orifice discharge coefficient from standard orifice C(sub s)(sup 1) to the discharge coefficient from the reverse flow C(sub s) is always less than unity with increasing ratio of box area to orifice area. Even for areas as low as twenty, the ratios of the coefficients are not much less than unity. It is probable, however, that when the ratio of box area is less than twenty, the ratio of discharge coefficients would be greatly reduced. Specific results are given for the case of an apparatus for the laboratory testing of superchargers.

5. [Fourth branchial cleft deformity with skin orifice: a series of 10 cases].

PubMed

Huang, S L; Zhang, B; Chen, L S; Liang, L; Luo, X N; Lu, Z M; Zhang, S Y

2016-10-07

Objective: To report rare cases of congenital neck cutaneous sinus with an orifice near the sternoclavicular joint and to investigate their origins and managements. Methods: A total of ten patients with congenital neck cutaneous sinus having an orifice near the sternoclavicular joint treated in the Guangdong General Hospital from January 2010 to June 2015 were retrospectively analyzed. Results: There four boys and six girls, aging from 11 months to 96 months with an average of 33.4 months, and they had a common feature showing a congenital cutaneous sinus with an orifice near sternoclavicular joint. Discharge of pus from the orifice or abscess formation was commonly seen soon after infection. With bacteriological study, staphylococcus aureus was positive in five cases and klebsiella pneumonia in a case. Another orifice of fistula/sinus was not depicted in pyriform with barium swallow X-ray in five cases Ultrasound studies of three cases demonstrated anechoic (i.e., nearly black) and solid-cystic lesion near sternoclavicular joint with posterior acoustic enhancement. Magnetic resonance imaging (MRI) showed isointensity of the lesion on T1 and T2 weighted images with heterogeneous enhancement and a close relationship with sternoclavicular joint. All patients underwent laryngoscopic examination, which showed no orifice of sinus in pyriform at same side. Surgical resection of fistula/sinus was performed in all cases. The lengths of the fistula varied from 5 mm to 22 mm with an average of 11 mm. Postoperative pathological examination showed all specimens were accordance with fistula. No complications were noticed. Recurrence was not observed in the cases by following-up of 6 months to 70 months (median: 33 months). Conclusion: Congenital neck cutaneous sinus with orifice near the sternoclavicular joint maybe a special clinical phenotype of the fourth branchial cleft sinus with skin orifice in cervicothoracic junction. Differential diagnoses between low cervical diseases

6. Preference pulses and the win-stay, fix-and-sample model of choice.

PubMed

Hachiga, Yosuke; Sakagami, Takayuki; Silberberg, Alan

2015-11-01

Two groups of six rats each were trained to respond to two levers for a food reinforcer. One group was trained on concurrent variable-ratio 20 extinction schedules of reinforcement. The second group was trained on a concurrent variable-interval 27-s extinction schedule. In both groups, lever-schedule assignments changed randomly following reinforcement; a light cued the lever providing the next reinforcer. In the next condition, the light cue was removed and reinforcer assignment strictly alternated between levers. The next two conditions redetermined, in order, the first two conditions. Preference pulses, defined as a tendency for relative response rate to decline to the just-reinforced alternative with time since reinforcement, only appeared during the extinction schedule. Although the pulse's functional form was well described by a reinforcer-induction equation, there was a large residual between actual data and a pulse-as-artifact simulation (McLean, Grace, Pitts, & Hughes, 2014) used to discern reinforcer-dependent contributions to pulsing. However, if that simulation was modified to include a win-stay tendency (a propensity to stay on the just-reinforced alternative), the residual was greatly reduced. Additional modifications of the parameter values of the pulse-as-artifact simulation enabled it to accommodate the present results as well as those it originally accommodated. In its revised form, this simulation was used to create a model that describes response runs to the preferred alternative as terminating probabilistically, and runs to the unpreferred alternative as punctate with occasional perseverative response runs. After reinforcement, choices are modeled as returning briefly to the lever location that had been just reinforced. This win-stay propensity is hypothesized as due to reinforcer induction.

7. Modeling of early stages of island growth during pulsed deposition: Role of closed compact islands

SciTech Connect

Kotrla, M.; Masin, M.

2011-03-24

After a brief review of recent modeling of growth during Pulsed Laser Deposition (PLD), we present the study of a role of adatom interactions on growth of surface islands during PLD in submonolayer regime. We employ kinetic Monte Carlo simulation with reversible growth. Attachment of monomers to islands is irreversible at low temperatures while it becomes reversible at higher temperatures, small islands become unstable with growing temperature. In the case of real system we have to take into account not only diffusion of monomers but also diffusivity of dimers and larger clusters and theirs stability. Our new code allows us to study processes which proceed on different time scales which are typical in PLD experiments: fast deposition (on scale order of 10{sup -5} s) during individual pulses, and relaxation of a system between pulses (on scale order of 0.1 s). We calculate and compare the temperature dependence of island density for two modes pulsed deposition and continuous Molecular Beam Epitaxy (MBE) growth. The island densities in PLD mode are substantially higher than in MBE mode, provided the temperature is sufficiently high. In the case of PLD, we observe anomalous temperature dependence of the island density in a certain temperature interval. It is due to the interplay between a cluster decay time and an interval between pulses. The cluster decay time depends not only on temperature but also on clusters size and shape. The anomalous behavior is caused by the temperature limited stability of the closed--compact clusters. This scenario was revealed for the simplified model with only nearest-neighbor interaction. Now, it is elucidated further and we also include interaction to second and third neighbors. We analyze role of the closed-compact surface island in kinetics of both growth modes. Furthermore, by varying interactions energies, diffusion barrier and parameters of deposition, we compare results of simulations with the PLD experiment for Fe/Mo system.

8. Analysis based on global model of nitrogen plasma produced by pulsed microwave at low pressure

SciTech Connect

Qiu, Feng; Yan, Eryan Meng, Fanbao; Ma, Hongge; Liu, Minghai

2015-07-15

This paper analyzes certain evolution processes in nitrogen plasmas discharged using pulsed microwaves at low pressure. Comparing the results obtained from the global model incorporating diffusion and the microwave transmission method, the temporal variation of the electron density is analyzed. With a discharge pressure of 300 Pa, the results obtained from experiments and the global model calculation show that when the discharge begins the electron density in the plasma rises quickly, to a level above the critical density corresponding to the discharge microwave frequency, but falls slowly when the discharge microwave pulse is turned off. The results from the global model also show that the electron temperature increases rapidly to a peak, then decays after the electron density reaches the critical density, and finally decreases quickly to room temperature when the discharge microwave pulse is turned off. In the global model, the electron density increases because the high electron temperature induces a high ionization rate. The decay of the electron density mainly comes from diffusion effect.

9. Modeling of beam-target interaction during pulsed electron beam ablation of graphite: Case of melting

Ali, Muddassir; Henda, Redhouane

2017-02-01

A one-dimensional thermal model based on a two-stage heat conduction equation is employed to investigate the ablation of graphite target during nanosecond pulsed electron beam ablation. This comprehensive model accounts for the complex physical phenomena comprised of target heating, melting and vaporization upon irradiation with a polyenergetic electron beam. Melting and vaporization effects induced during ablation are taken into account by introducing moving phase boundaries. Phase transition induced during ablation is considered through the temperature dependent thermodynamic properties of graphite. The effect of electron beam efficiency, power density, and accelerating voltage on ablation is analyzed. For an electron beam operating at an accelerating voltage of 15 kV and efficiency of 0.6, the model findings show that the target surface temperature can reach up to 7500 K at the end of the pulse. The surface begins to melt within 25 ns from the pulse start. For the same process conditions, the estimated ablation depth and ablated mass per unit area are about 0.60 μm and 1.05 μg/mm2, respectively. Model results indicate that ablation takes place primarily in the regime of normal vaporization from the surface. The results obtained at an accelerating voltage of 15 kV and efficiency factor of 0.6 are satisfactorily in good accordance with available experimental data in the literature.

10. Full 3D modelling of pulse propagation enables efficient nonlinear frequency conversion with low energy laser pulses in a single-element tripler.

PubMed

Kardaś, Tomasz M; Nejbauer, Michał; Wnuk, Paweł; Resan, Bojan; Radzewicz, Czesław; Wasylczyk, Piotr

2017-02-22

Although new optical materials continue to open up access to more and more wavelength bands where femtosecond laser pulses can be generated, light frequency conversion techniques are still indispensable in filling the gaps on the ultrafast spectral scale. With high repetition rate, low pulse energy laser sources (oscillators) tight focusing is necessary for a robust wave mixing and the efficiency of broadband nonlinear conversion is limited by diffraction as well as spatial and temporal walk-off. Here we demonstrate a miniature third harmonic generator (tripler) with conversion efficiency exceeding 30%, producing 246 fs UV pulses via cascaded second order processes within a single laser beam focus. Designing this highly efficient and ultra compact frequency converter was made possible by full 3-dimentional modelling of propagation of tightly focused, broadband light fields in nonlinear and birefringent media.

11. Full 3D modelling of pulse propagation enables efficient nonlinear frequency conversion with low energy laser pulses in a single-element tripler

PubMed Central

Kardaś, Tomasz M.; Nejbauer, Michał; Wnuk, Paweł; Resan, Bojan; Radzewicz, Czesław; Wasylczyk, Piotr

2017-01-01

Although new optical materials continue to open up access to more and more wavelength bands where femtosecond laser pulses can be generated, light frequency conversion techniques are still indispensable in filling the gaps on the ultrafast spectral scale. With high repetition rate, low pulse energy laser sources (oscillators) tight focusing is necessary for a robust wave mixing and the efficiency of broadband nonlinear conversion is limited by diffraction as well as spatial and temporal walk-off. Here we demonstrate a miniature third harmonic generator (tripler) with conversion efficiency exceeding 30%, producing 246 fs UV pulses via cascaded second order processes within a single laser beam focus. Designing this highly efficient and ultra compact frequency converter was made possible by full 3-dimentional modelling of propagation of tightly focused, broadband light fields in nonlinear and birefringent media. PMID:28225007

12. Full 3D modelling of pulse propagation enables efficient nonlinear frequency conversion with low energy laser pulses in a single-element tripler

Kardaś, Tomasz M.; Nejbauer, Michał; Wnuk, Paweł; Resan, Bojan; Radzewicz, Czesław; Wasylczyk, Piotr

2017-02-01

Although new optical materials continue to open up access to more and more wavelength bands where femtosecond laser pulses can be generated, light frequency conversion techniques are still indispensable in filling the gaps on the ultrafast spectral scale. With high repetition rate, low pulse energy laser sources (oscillators) tight focusing is necessary for a robust wave mixing and the efficiency of broadband nonlinear conversion is limited by diffraction as well as spatial and temporal walk-off. Here we demonstrate a miniature third harmonic generator (tripler) with conversion efficiency exceeding 30%, producing 246 fs UV pulses via cascaded second order processes within a single laser beam focus. Designing this highly efficient and ultra compact frequency converter was made possible by full 3-dimentional modelling of propagation of tightly focused, broadband light fields in nonlinear and birefringent media.

13. Noise generated by cavitating single-hole and multi-hole orifices in a water pipe

Testud, P.; Moussou, P.; Hirschberg, A.; Aurégan, Y.

2007-02-01

This paper presents an experimental study of the acoustical effects of cavitation caused by a water flow through an orifice. A circular-centered single-hole orifice and a multi-hole orifice are tested. Experiments are performed under industrial conditions: the pressure drop across the orifice varies from 3 to 30 bar, corresponding to cavitation numbers from 0.74 to 0.03. Two regimes of cavitation are discerned. In each regime, the broadband noise spectra obtained far downstream of the orifice are presented. A nondimensional representation is proposed: in the intermediate ‘developed cavitation’ regime, spectra collapse reasonably well; in the more intense ‘super cavitation’ regime, spectra depend strongly on the quantity of air remaining in the water downstream of the orifice, which is revealed by the measure of the speed of sound at the downstream transducers. In the ‘developed cavitation’ regime, whistling associated with periodic vortex shedding is observed. The corresponding Strouhal number agrees reasonably well with literature for single-phase flows. In the 'super cavitation’ regime, the whistling disappears.

14. Effect of Orifice Diameter on Bubble Generation Process in Melt Gas Injection to Prepare Aluminum Foams

Yuan, Jianyu; Li, Yanxiang; Wang, Ningzhen; Cheng, Ying; Chen, Xiang

2016-06-01

The bubble generation process in conditioned A356 alloy melt through submerged spiry orifices with a wide diameter range (from 0.07 to 1.0 mm) is investigated in order to prepare aluminum foams with fine pores. The gas flow rate and chamber pressure relationship for each orifice is first determined when blowing gas in atmospheric environment. The effects of chamber pressure ( P c) and orifice diameter ( D o) on bubble size are then analyzed separately when blowing gas in melt. A three-dimensional fitting curve is obtained illustrating both the influences of orifice diameter and chamber pressure on bubble size based on the experimental data. It is found that the bubble size has a V-shaped relationship with orifice diameter and chamber pressure neighboring the optimized parameter ( D o = 0.25 mm, P c = 0.4 MPa). The bubble generation mechanism is proposed based on the Rayleigh-Plesset equation. It is found that the bubbles will not be generated until a threshold pressure difference is reached. The threshold pressure difference is dependent on the orifice diameter, which determines the time span of pre-formation stage and bubble growth stage.

15. Accuracy of various methods of localization of the orifice of the coronary sinus at electrophysiologic study.

PubMed

Davis, L M; Byth, K; Lau, K C; Uther, J B; Richards, D A; Ross, D L

1992-08-01

The coronary sinus (CS) orifice is an important reference point for determining electrode and, thereby, accessory pathway location at electrophysiologic study. The reliability of fluoroscopic landmarks used to identify the CS orifice is not known. This study compared the accuracy of several fluoroscopic landmarks for identifying the CS orifice with the location defined by radiopaque contrast injection of the CS. Forty patients were studied. Radiographic markers of the CS orifice that were examined included: (1) the point at which the CS catheter prolapsed during advancement, (2) the point of maximum convexity of the CS catheter when a superior vena caval approach was used, (3) the right side of the ventricular septum, and (4) the relation to the underlying vertebrae. The least-significant difference method of multiple comparisons was used for statistical analysis. The point at which the CS catheter prolapsed was the most accurate noncontrast method for determining the location of the CS orifice (p less than 0.05), but was possible without the use of excessive force in only 48% of patients. The point of catheter prolapse was a median of 1 mm (range 0 to 11) from the true location of the os. Errors with other examined landmarks ranged up to 3 cm. Identification of the CS orifice is best performed by radiopaque contrast injection. The point of prolapse during catheter advancement in the CS is an accurate alternative when contrast injection is not feasible. Other noncontrast fluoroscopic landmarks are less reliable and are best avoided.(ABSTRACT TRUNCATED AT 250 WORDS)

16. Fine structures around the orifice of the intercostal artery of the rabbit thoracic aorta.

PubMed

Emura, S; Masuko, S; Sunaga, T

1992-03-01

In hypercholesterolemic rabbits, atherosclerotic lesions easily occur in the thoracic aorta, especially at the distal and lateral sides of the walls around the orifices of the dorsal intercostal arteries. In order to examine whether some special structures that lead to atherosclerotic lesions are present even in normal conditions, the authors investigated the morphologic features around the orifice of the intercostal artery of 20 normal rabbit aortae under electron microscopy. The endothelial cells were generally fusiform but tended to be round and have a cobblestone-like appearance at the lateral side. There was intimal protrusion at the distal and lateral sides of the orifice, where the distribution and arrangement of elastic fibers and smooth muscle cells were different from those at the proximal side. At the proximal edge of the orifice, elastic fibers formed a thick plate-like internal elastic lamina beneath the endothelial cells. On the other hand, at the distal and lateral sides, elastic fibers formed close-meshed structures over the proper plate-like internal elastic lamina. These results indicate that the aortic walls at the distal and lateral sides of the orifice are structurally different from those at other regions even in normal conditions and suggest the involvement of special structures at the distal and lateral sides of the orifice in atherogenesis.

17. Comprehensive modeling of structural modification induced by a femtosecond laser pulse inside fused silica glass

Najafi, Somayeh; Sadat Arabanian, Atoosa; Massudi, Reza

2016-06-01

A comprehensive theoretical model is proposed based on equations describing the nonlinear propagation of an ultrashort pulse inside transparent material, electron density evolution, non-Fourier heat conduction, and thermo-elasto plastic displacement which are respectively solved by various methods. These methods include the split-step finite difference technique and alternating-direction implicit algorithm, fourth-order Range-Kutta algorithm, hybrid finite-element method/finite-difference method, and finite-element method in both space and time to achieve refractive index changes. The whole chain of processes occurring in the interaction of a focused ultrashort laser pulse with fused silica glass in prevalent conditions of micromachining applications is numerically investigated. By optimizing the numerical method and by using an adaptive mesh approach, the execution time of the program is significantly reduced so that the calculations are done at each time step in a fraction of a second. Simulation results show that the energy and duration of the input pulse are very important parameters in induced changes, but the chirp of the input pulse is not an effective parameter. Consequently, by appropriate setting of those parameters one can design a desired refractive index profile.

18. A multiphase model for pulsed ns-laser ablation of copper in an ambient gas

SciTech Connect

Autrique, D.; Chen, Z.; Alexiades, V.; Bogaerts, A.; Rethfeld, B.

2012-07-30

Laser ablation in an ambient gas is nowadays used in a growing number of applications, such as chemical analysis and pulsed laser deposition. Despite the many applications, the technique is still poorly understood. Therefore models describing the material evolution in time during short pulse laser irradiation can be helpful to unravel the puzzle and finally result in the optimization of the related applications. In the present work, a copper target is immersed in helium, initially set at atmospheric pressure and room temperature. Calculations are performed for a Gaussian-shaped laser pulse with a wavelength of 532 nm, full width at half maximum of 6 ns, and laser fluences up to 10 J/cm{sup 2}. In order to describe the transient behaviour in and above the copper target, hydrodynamic equations are solved. An internal energy method accounting for pressure relaxation is applied for the description of the target. In the plume domain a set of conservation equations is solved, assuming local thermodynamic equilibrium. Calculated crater depths and transmission profiles are compared with experimental results and similar trends are found. Our calculations indicate that for the laser fluence regime under study, explosive boiling could play a fundamental role in the plasma formation of metals under ns-pulsed laser irradiation.

19. Comparisons of wing pressure distribution from flight tests of flush and external orifices for Mach numbers from 0.50 to 0.97

NASA Technical Reports Server (NTRS)

Montoya, L. C.; Lux, D. P.

1975-01-01

Wing pressure distributions obtained in flight with flush orifice and external tubing orifice installations for Mach numbers from 0.50 to 0.97 are compared. The procedure used to install the external tubing orifice is discussed. The results indicate that external tubing orifice installations can give useful results.

20. Small-Scale Spray Releases: Orifice Plugging Test Results

SciTech Connect

Mahoney, Lenna A.; Gauglitz, Phillip A.; Blanchard, Jeremy; Kimura, Marcia L.; Kurath, Dean E.

2012-09-01

One of the events postulated in the hazard analysis at the Waste Treatment and Immobilization Plant (WTP) and other U.S. Department of Energy (DOE) nuclear facilities, is a breach in process piping that produces aerosols with droplet sizes in the respirable range. The current approach for predicting the size and concentration of aerosols produced in a spray leak involves extrapolating from correlations published in the literature. These correlations are based on results obtained from small engineered spray nozzles using pure liquids with Newtonian fluid behavior. The narrow ranges of physical properties on which the correlations are based do not cover the wide range of slurries and viscous materials present in the WTP and across processing facilities in the DOE complex. Two key technical areas were identified where testing results were needed to improve the technical basis by reducing the uncertainty introduced by extrapolating existing literature results. The first technical need was to quantify the role of slurry particles in small breaches in which the slurry particles may plug and result in substantially reduced, or even negligible, respirable fraction formed by high pressure sprays. The second technical need was to determine the aerosol droplet size distribution and volume from prototypic breaches and fluids, specifically including sprays from larger breaches with slurries where data from the literature are largely absent. To address these technical areas, small- and large-scale test stands were constructed and operated with simulants to determine the aerosol release fractions and aerosol generation rates from a range of breach sizes and geometries. The properties of the simulants represented the range of properties expected in the WTP process streams and included water, sodium salt solutions, slurries containing boehmite or gibbsite, and a hazardous chemical simulant. The effect of anti-foam agents (AFA) was assessed with most of the simulants. Orifices

1. Limits of applicability of a two-temperature model under nonuniform heating of metal by an ultrashort laser pulse

Polyakov, D. S.; Yakovlev, E. B.

2015-10-01

The heating of metals (silver and aluminium) by ultrashort laser pulses is analysed proceeding from a spatially nonuniform kinetic equation for the electron distribution function. The electron subsystem thermalisation is estimated in a wide range of absorbed pulse energy density. The limits of applicability are determined for the two-temperature model.

2. Limits of applicability of a two-temperature model under nonuniform heating of metal by an ultrashort laser pulse

SciTech Connect

Polyakov, D S; Yakovlev, E B

2015-10-31

The heating of metals (silver and aluminium) by ultrashort laser pulses is analysed proceeding from a spatially nonuniform kinetic equation for the electron distribution function. The electron subsystem thermalisation is estimated in a wide range of absorbed pulse energy density. The limits of applicability are determined for the two-temperature model. (interaction of laser radiation with matter)

3. Measurement and Modeling of Dispersive Pulse Propagation in Drawn Wire Waveguides

NASA Technical Reports Server (NTRS)

Madaras, Eric I.; Kohl, Thomas W.; Rogers, Wayne P.

1995-01-01

An analytical model of dispersive pulse propagation in semi-infinite cylinders due to transient axially symmetric end conditions has been experimentally investigated. Specifically, the dispersive propagation of the first axially symmetric longitudinal mode in thin wire waveguides, which have ends in butt contact with longitudinal piezoelectric ultrasonic transducers, is examined. The method allows for prediction of a propagated waveform given a measured source waveform, together with the material properties of the cylinder. Alternatively, the source waveform can be extracted from measurement of the propagated waveform. The material properties required for implementation of the pulse propagation model are determined using guided wave phase velocity measurements. Hard tempered aluminum 1100 and 304 stainless steel wires, with 127, 305, and 406 micron diam., were examined. In general, the drawn wires were found to behave as transversely isotropic media.

4. Measurement and modeling of dispersive pulse propagation in draw wire waveguides

NASA Technical Reports Server (NTRS)

Madaras, Eric I.; Kohl, Thomas W.; Rogers, Wayne P.

1995-01-01

An analytical model of dispersive pulse propagation in semi-infinite cylinders due to transient axially symmetric end conditions has been experimentally investigated. Specifically, the dispersive propagation of the first axially symmetric longitudinal mode in thin wire waveguides, which have ends in butt contact with longitudinal piezoelectric ultrasonic transducers, is examined. The method allows for prediction of a propagated waveform given a measured source waveform, together with the material properties of the cylinder. Alternatively, the source waveform can be extracted from measurement of the propagated waveform. The material properties required for implementation of the pulse propagation model are determined using guided wave phase velocity measurements. Hard tempered aluminum 1100 and 304 stainless steel wires, with 127, 305, and 406 micron diam., were examined. In general, the drawn wires were found to behave as transversely isotropic media.

5. Pulsed radiolysis of model aromatic polymers and epoxy based matrix materials

NASA Technical Reports Server (NTRS)

Gupta, A.; Moacanin, J.; Liang, R.; Coulter, D.

1982-01-01

Models of primary processes leading to deactivation of energy deposited by a pulse of high energy electrons were derived for epoxy matrix materials and polyl-vinyl naphthalene. The basic conclusion is that recombination of initially formed charged states is complete within 1 nanosecond, and subsequent degradation chemistry is controlled by the reactivity of these excited states. Excited states in both systems form complexes with ground state molecules. These excimers or exciplexes have their characteristics emissive and absorptive properties and may decay to form separated pairs of ground state molecules, cross over to the triplet manifold or emit fluorescence. ESR studies and chemical analyses subsequent to pulse radiolysis were performed in order to estimate bond cleavage probabilities and net reaction rates. The energy deactivation models which were proposed to interpret these data have led to the development of radiation stabilization criteria for these systems.

6. Arterial pulse pressure amplification described by means of a nonlinear wave model: characterization of human aging

Alfonso, M.; Cymberknop, L.; Armentano, R.; Pessana, F.; Wray, S.; Legnani, W.

2016-04-01

The representation of blood pressure pulse as a combination of solitons captures many of the phenomena observed during its propagation along the systemic circulation. The aim of this work is to analyze the applicability of a compartmental model for propagation regarding the pressure pulse amplification associated with arterial aging. The model was applied to blood pressure waveforms that were synthesized using solitons, and then validated by waveforms obtained from individuals from differentiated age groups. Morphological changes were verified in the blood pressure waveform as a consequence of the aging process (i.e. due to the increase in arterial stiffness). These changes are the result of both a nonlinear interaction and the phenomena present in the propagation of nonlinear mechanic waves.

7. Incorporation of an energy equation into a pulsed inductive plasma acceleration model

Reneau, Jarred

Electric propulsion systems utilize electrical energy to produce thrust for spacecraft propulsion. These systems have multiple applications ranging from Earth orbit North-South station keeping to solar system exploratory missions such as NASA's Discovery, New Frontiers, and Flagship class missions that focus on exploring scientifically interesting targets. In an electromagnetic thruster, a magnetic field interacting with current in an ionized gas (plasma) accelerates the propellant to produce thrust. Pulsed inductive thrusters rely on an electrodeless discharge where both the magnetic field in the plasma and the plasma current are induced by a time-varying current in an external circuit. The multi-dimensional acceleration model for a pulsed inductive plasma thruster consists of a set of circuit equations describing the electrical behavior of the thruster coupled to a one-dimensional momentum equation that allow for estimating thruster performance. Current models lack a method to account for the time-varying energy distribution in an inductive plasma accelerator.

8. The fan beam model for the pulse evolution of PSR J0737-3039B

Saha, L.; Dyks, J.

2017-01-01

Average radio pulse profile of a pulsar B in a double pulsar system PSR J0737-3039A/B exhibits an interesting behaviour. During the observation period between 2003 and 2009, the profile evolves from a single-peaked to a double-peaked form, following disappearance in 2008 indicating that the geodetic precession of the pulsar is a possible origin of such behaviour. The known pulsar beam models can be used to determine the geometry of PSR J0737-3039B in the context of the precession. We study how the fan-beam geometry performs in explaining the observed variations of the radio profile morphology. It is shown that the fan beam can successfully reproduce the observed evolution of the pulse width, and should be considered as a serious alternative for the conal-like models.

9. Pressure and flow characteristics of restrictive flow orifice devices.

SciTech Connect

Shrouf, Roger D.

2003-06-01

A Restrictive Flow Orifice (RFO) can be used to enhance the safe design of a pressure system in several ways. Pressure systems frequently incorporate a regulator and relief valve to protect the downstream equipment from accidental overpressure caused by regulator failure. Analysis frequently shows that in cases of high-flow regulator failure, the downstream pressure may rise significantly above the set pressure of the relief valve. This is due to limited flow capacity of the relief valve. A different regulator or relief valve may need to be selected. A more economical solution to this problem is to use an RFO to limit the maximum system flow to acceptable limits within the flow capacity of the relief valve, thereby enhancing the overpressure protection of laboratory equipment. An RFO can also be used to limit the uncontrolled release of system fluid (gas or liquid) upon component or line failure. As an example, potential asphyxiation hazards resultant from the release of large volumes of inert gas from a 'house' nitrogen system can be controlled by the use of an RFO. This report describes a versatile new Sandia-designed RFO available from the Swagelok Company and specifies the gas flow characteristics of this device. Two sizes, 0.010 and 0.020 inch diameter RFOs are available. These sizes will allow enhanced safety for many common applications. This new RFO design are now commercially available and provide advantages over existing RFOs: a high pressure rating (6600 psig); flow through the RFO is equal for either forward or reverse directions; they minimize the potential for leakage by incorporating the highest quality threaded connections; and can enhance the safety of pressure systems.

10. Reversal of the Hartmann procedure through only a stomal orifice.

PubMed

Aydin, Cemalettin; Olmez, Aydemir; Isik, Sevil; Sumer, Fatih; Kayaalp, Cuneyt

2011-06-01

We performed reversal of the Hartmann procedure only through the stoma site and we did not use either any other incision nor laparoscopic assistance. A total of 8 patients (7 males), ages between 23 and 80 years, were treated by means of a defined technique. The indications of the Hartmann procedure were sigmoid volvulus (4), sigmoid cancer obstruction (2), rectal trauma (1), and Fournier gangrene (one). The duration from the first procedure was a mean of 5 months (range, 2 to 8 months). The length of the rectal stump was at least 5 cm over the pelvic peritoneum and the body mass indices of all patients were less than 30 kg/m². The diameter of the stoma opening was a mean of 50 mm (range, 40 to 55 mm). Incision extensions from the stomal orifice (accepted as conversion) were needed for two cases as a result of injury on the intestine and inability to identify the distal bowel stump (25%). The mean operative blood loss and duration of operation were 50 mL (range, 30 to 100 mL) and 65 minutes (range, 45 to 80 minutes), respectively. Fecal discharge of all patients was weighed before hospital discharge and the length of postoperative hospital stay was a mean of 5.5 days (range, 4 to 9 days). Neither anastomosis leakage nor surgical site infections were observed in any of the patients and all had an uneventful postoperative course. The described technique can be the least invasive one than the previously described techniques for the reversal of the Hartmann procedure by only using the stoma site, particularly for nonobese patients with a long distal rectal stump.

11. Natural orifice translumenal endoscopic surgery applications in clinical practice.

PubMed

Coomber, Ross S; Sodergren, Mikael H; Clark, James; Teare, Julian; Yang, Guang-Zhong; Darzi, Ara

2012-03-16

To review natural orifice translumenal endoscopic surgery (NOTES) applications in clinical practice and assess the evidence base for each application as reported in the literature. An electronic literature search was performed. Inclusion criteria were publications relating to NOTES applications in humans. For each type of operation the highest level of evidence available for clinical NOTES publications was evaluated. Morbidity and short-term operative outcomes were compared with gold standard published evidence where available. Finally, registered trials recruiting patients for NOTES applications were identified. Human NOTES publications with the highest level of evidence in each application are identified. There were no RCTs in the literature to date. The strongest evidence came in the form of large, multi-centre trials with 300-500 patients. The results are encouraging, comparable with gold standard techniques on morbidity and mortality. While short-term operative outcomes were also similar when compared to the gold standard techniques, other than improved cosmesis little else can definitely be concluded as a clear benefit of a NOTES procedure. The most common procedures are cholecystectomy, appendicectomy and peritoneoscopy mainly performed via transvaginal access. It is evident that morbidity appears to be higher when the transgastric route is used. The safety profile of hybrid NOTES transvaginal procedures is beginning to be confirmed as is evident from the large number of procedures presented in this review. A number of authors have presented work on pure NOTES procedures but the results are inconsistent and thus the vast majority of NOTES procedures worldwide are performed in a hybrid fashion with a variable amount of laparoscopy. This review of the clinical applications of NOTES summarises the growing evidence behind this surgical discipline and highlights NOTES procedures with an acceptable safety profile.

12. Model and Subcomponent Development for a Pulse-Combustor-Driven Microgenerator

DTIC Science & Technology

2007-11-02

emphasis was on performing modeling, and numerical simulations of the pulse combustors and free piston generator and the development of magnetic...subcomponents. During the last phase of the project (under a no-cost extension) some limited simulations of close-loop control of the engine performance...time and depth into the wall material. An apparent change in the slope of temperature curve can be seen on the interface between the chamber’s steel

13. Modeling of asymmetric pulsed phenomena in dielectric-barrier atmospheric-pressure glow discharges

SciTech Connect

Ha Yan; Wang Huijuan; Wang Xiaofei

2012-01-15

Asymmetric current pulses in dielectric-barrier atmospheric-pressure glow discharges are investigated by a self-consistent, one-dimensional fluid model. It is found that the glow mode and Townsend mode can coexist in the asymmetric discharge even though the gas gap is rather large. The reason for this phenomenon is that the residual space charge plays the role of anode and reduces the gap width, resulting in the formation of a Townsend discharge.

14. A statistical model of the photomultiplier gain process with applications to optical pulse detection

NASA Technical Reports Server (NTRS)

Tan, H. H.

1982-01-01

A Markov diffusion model was used to determine an approximate probability density for the random gain. This approximate density preserves the correct second-order statistics and appears to be in reasonably good agreement with experimental data. The receiver operating curve for a pulse counter detector of PMT cathode emission events was analyzed using this density. The error performance of a simple binary direct detection optical communication system was also derived. Previously announced in STAR as N82-25100

15. A statistical model of the photomultiplier gain process with applications to optical pulse detection

NASA Technical Reports Server (NTRS)

Tan, H. H.

1982-01-01

A Markov diffusion model was used to determine an approximate probability density for the random gain. This approximate density preserves the correct second-order statistics and appears to be in reasonably good agreement with experimental data. The receiver operating curve for a pulse counter detector of PMT cathode emission events was analyzed using this density. The error performance of a simple binary direct detection optical communication system was also derived.

16. Sensorless Modeling of Varying Pulse Width Modulator Resolutions in Three-Phase Induction Motors

PubMed Central

Marko, Matthew David; Shevach, Glenn

2017-01-01

A sensorless algorithm was developed to predict rotor speeds in an electric three-phase induction motor. This sensorless model requires a measurement of the stator currents and voltages, and the rotor speed is predicted accurately without any mechanical measurement of the rotor speed. A model of an electric vehicle undergoing acceleration was built, and the sensorless prediction of the simulation rotor speed was determined to be robust even in the presence of fluctuating motor parameters and significant sensor errors. Studies were conducted for varying pulse width modulator resolutions, and the sensorless model was accurate for all resolutions of sinusoidal voltage functions. PMID:28076418

17. Sensorless Modeling of Varying Pulse Width Modulator Resolutions in Three-Phase Induction Motors.

PubMed

Marko, Matthew David; Shevach, Glenn

2017-01-01

A sensorless algorithm was developed to predict rotor speeds in an electric three-phase induction motor. This sensorless model requires a measurement of the stator currents and voltages, and the rotor speed is predicted accurately without any mechanical measurement of the rotor speed. A model of an electric vehicle undergoing acceleration was built, and the sensorless prediction of the simulation rotor speed was determined to be robust even in the presence of fluctuating motor parameters and significant sensor errors. Studies were conducted for varying pulse width modulator resolutions, and the sensorless model was accurate for all resolutions of sinusoidal voltage functions.

18. Comparison of two models of a double inlet miniature pulse tube refrigerator: Part A thermodynamics

Nika, Philippe; Bailly, Yannick

2002-10-01

The cooling of electronic components is of great interest to improve their capabilities, especially for CMOS components or infrared sensors. The purpose of this paper is to present the design and the optimization of a miniature double inlet pulse tube refrigerator (DIPTR) dedicated to such applications. Special precautions have to be considered in modeling the global functioning of small scale DIPTR systems and also in estimating the net cooling power. In fact, thermal gradients are greater than those observed in normal scale systems, and moreover, because of the small dimensions of ducts (diameter), the pulse tube cannot be assumed to be adiabatic. Hence thermal heat conduction phenomena must be considered. Besides dead volumes introduced by junctions and capillaries cannot be neglected any more in front of the volume of the gas tube itself. The hydrodynamic and thermal behaviors of the cooler are predicted by means of two different approaches: a classical thermodynamic model and a model based on an electrical analogy. The results of these analysis are tested and criticized by comparing them with experimental data obtained on a small commercial pulse tube refrigerator.

19. Realistic modeling of the pulse profile of PSR J0737-3039A

SciTech Connect

Perera, B. B. P.; Kim, C.; McLaughlin, M. A.; Ferdman, R. D.; Kramer, M.; Freire, P. C. C.; Stairs, I. H.; Possenti, A.

2014-05-20

The Double Pulsar, PSR J0737-3039A/B, is a unique system in which both neutron stars have been detected as radio pulsars. As shown in Ferdman et al., there is no evidence for pulse profile evolution of the A pulsar, and the geometry of the pulsar was fit well with a double-pole circular radio beam model. Assuming a more realistic polar cap model with a vacuum retarded dipole magnetosphere configuration including special relativistic effects, we create synthesized pulse profiles for A given the best-fit geometry from the simple circular beam model. By fitting synthesized pulse profiles to those observed from pulsar A, we constrain the geometry of the radio beam, namely the half-opening angle and the emission altitude, to be ∼30° and ∼10 neutron star radii, respectively. Combining the observational constraints of PSR J0737-3039A/B, we are able to construct the full three-dimensional orbital geometry of the Double Pulsar. The relative angle between the spin axes of the two pulsars (Δ{sub S}) is estimated to be ∼(138° ± 5°) at the current epoch and will likely remain constant until tidal interactions become important in ∼85 Myr, at merger.

20. Endometrial thermal balloon ablation using a high temperature, pulsed system: a mathematical model.

PubMed

Reinders, Daniel M; Baldwin, Susan A; Bert, Joel L

2003-12-01

A new endometrial thermal balloon ablation treatment for menorrhagia is modeled mathematically to predict its efficacy and safety. A device preheats a fluid to 173 degrees C within a reservoir external to the uterus, and then pulses this fluid without further heating between the reservoir and the balloon for 2.1 min of treatment time. The model predicted this treatment to result in consistent immediate tissue death (coagulation) depths of 3.4 +/- 0.1 mm for uterine cavities of 7 to 26 mL, and that eventual necrosis (tissue death that would occur 1-5 days post burn) may occur to depths of 6.5 +/- 0.2 mm. Whereas, burn depths varied with uterine cavity volume when a low temperature treatment (constant 75 degrees C for 15 min) was modeled (2.3-2.9 mm and 6.8-8.2 mm, for immediate tissue death and eventual necrosis respectively). Similarly, the high temperature, pulsed treatment was less sensitive to blood perfusion rate than the low temperature treatment. Predicted eventual necrosis depth was 1.5 mm less for the high temperature, pulsed treatment than that predicted for a low temperature treatment (constant 87 degrees C for 7 min) for the same immediate tissue death depth (3.5 mm), indicating that the new high temperature treatment may result in less damage to non targeted tissues.

1. Evaluating the use of a continuous approximation for model-based quantification of pulsed chemical exchange saturation transfer (CEST)

Tee, Y. K.; Khrapitchev, A. A.; Sibson, N. R.; Payne, S. J.; Chappell, M. A.

2012-09-01

Many potential clinical applications of chemical exchange saturation transfer (CEST) have been studied in recent years. However, due to various limitations such as specific absorption rate guidelines and scanner hardware constraints, most of the proposed applications have yet to be translated into routine diagnostic tools. Currently, pulsed CEST which uses multiple short pulses to perform the saturation is the only viable irradiation scheme for clinical translation. However, performing quantitative model-based analysis on pulsed CEST is time consuming because it is necessary to account for the time dependent amplitude of the saturation pulses. As a result, pulsed CEST is generally treated as continuous CEST by finding its equivalent average field or power. Nevertheless, theoretical analysis and simulations reveal that the resulting magnetization is different when the different irradiation schemes are applied. In this study, the quantification of important model parameters such as the amine proton exchange rate from a pulsed CEST experiment using quantitative model-based analyses were examined. Two model-based approaches were considered - discretized and continuous approximation to the time dependent RF irradiation pulses. The results showed that the discretized method was able to fit the experimental data substantially better than its continuous counterpart, but the smaller fitted error of the former did not translate to significantly better fit for the important model parameters. For quantification of the endogenous CEST effect, such as in amide proton transfer imaging, a model-based approach using the average power equivalent saturation can thus be used in place of the discretized approximation.

2. Prediction of flow rates through an orifice at pressures corresponding to the transition between molecular and isentropic flow

SciTech Connect

DeMuth, S.F.; Watson, J.S.

1985-01-01

A model of compressible flow through an orifice, in the region of transition from free molecular to isentropic expansion flow, has been developed and tested for accuracy. The transitional or slip regime is defined as the conditions where molecular interactions are too many for free molecular flow modeling, yet not great enough for isentropic expansion flow modeling. Due to a lack of literature establishing a well-accepted model for predicting transitional flow, it was felt such work would be beneficial. The model is nonlinear and cannot be satisfactorily linearized for a linear regression analysis. Consequently, a computer routine was developed which minimized the sum of the squares of the residual flow for the nonlinear model. The results indicate an average accuracy within 15% of the measured flow throughout the range of test conditions. Furthermore, the results of the regression analysis indicate that the transitional regime lies between Knudsen numbers of approximately 2 and 45. 4 refs., 3 figs., 1 tab.

3. Laboratory model of the cardiovascular system for experimental demonstration of pulse wave propagation

Stojadinović, Bojana; Nestorović, Zorica; Djurić, Biljana; Tenne, Tamar; Zikich, Dragoslav; Žikić, Dejan

2017-03-01

The velocity by which a disturbance moves through the medium is the wave velocity. Pulse wave velocity is among the key parameters in hemodynamics. Investigation of wave propagation through the fluid-filled elastic tube has a great importance for the proper biophysical understanding of the nature of blood flow through the cardiovascular system. Here, we present a laboratory model of the cardiovascular system. We have designed an experimental setup which can help medical and nursing students to properly learn and understand basic fluid hemodynamic principles, pulse wave and the phenomenon of wave propagation in blood vessels. Demonstration of wave propagation allowed a real time observation of the formation of compression and expansion waves by students, thus enabling them to better understand the difference between the two waves, and also to measure the pulse wave velocity for different fluid viscosities. The laboratory model of the cardiovascular system could be useful as an active learning methodology and a complementary tool for understanding basic principles of hemodynamics.

4. Interaction of pulse laser radiation of 532 nm with model coloration layers for medieval stone artefacts

Colson, J.; Nimmrichter, J.; Kautek, W.

2014-05-01

Multilayer polychrome coatings on medieval and Renaissance stone artefacts represent substantial challenges in laser cleaning. Therefore, polychromic models with classical pigments, minium Pb22+PbO, zinc white (ZnO), and lead white ((PbCO3)2·Pb(OH)2) in an acrylic binder, were irradiated with a Q-switched Nd:YAG laser emitting at 532 nm. The studied medieval pigments exhibit strongly varying incubation behaviours directly correlated to their band gap energies. Higher band gaps beyond the laser photon energy of 2.3 eV require more incubative generation of defects for resonant transitions. A matching of the modification thresholds after more than four laser pulses was observed. Laser cleaning with multiple pulsing should not exceed ca. 0.05 J/cm2 when these pigments coexist in close spatial proximity.

5. An extended diffusive model for calculating thermal diffusivity from single monopole tokamak heat pulse propagation

SciTech Connect

Marinak, M. )

1990-02-01

The problem of deducing {chi}{sub e} from measurements of the propagation of a monopole heatpulse is considered. An extended diffusive model, which takes into account perturbed sources and sinks is extended to the case of a monopole heat input. {chi}{sub e} is expressed as a function of two observables, the heat pulse velocity and the radial damping rate. Two simple expressions valid for two different ranges of the radius of the poloidal waist of the beam power profile are given. The expressions are valid in the heat pulse measurement region, extending radially 0.05a beyond the beam power waist to near 0.6a. The inferred {chi}{sub e} is a local value, not an average value of the radial {chi}{sub e} profile. 7 refs., 6 figs., 1 tab.

6. 3-D Modeling of Modifications to the Z Accelerator for Generating Shaped Pulses

Pointon, Timothy D.; Savage, Mark E.; Harjes, Henry C.

2002-12-01

One option to temporally shape the power pulse at the load on the Z accelerator at Sandia National Laboratories is timing delays between the 36 pulse-forming lines. However, this can lead to the formation of magnetic nulls in the vacuum section, with the potential for greatly increasing electron losses to—and possibly damaging—the anode. Three-dimensional computer simulations are now being conducted to study this concern. The simulation geometry models a single level of Z, with a radial transmission line driven by nine parallel-plate lines. Every third line is driven early relative to the other six. Results from preliminary runs without particle emission are presented. Voltage and current diagnostics agree quite well with circuit simulations, and spatial field profiles illustrate the evolution of the magnetic nulls in detail.

7. Analytical solutions and moment analysis of chromatographic models for rectangular pulse injections.

PubMed

Qamar, Shamsul; Abbasi, Javeria N; Javeed, Shumaila; Shah, Munawar; Khan, Farman U; Seidel-Morgenstern, Andreas

2013-11-08

This work focuses on the analysis of two standard liquid chromatographic models, namely the lumped kinetic model and the equilibrium dispersive model. Analytical solutions, obtained by means of Laplace transformation, are derived for rectangular single solute concentration pulses of finite length and breakthrough curves injected under linear conditions. In order to analyze the solute transport behavior by means of the two models, the temporal moments up to fourth order are calculated from the Laplace-transformed solutions. The limiting cases of continuous injection and negligible mass transfer limitations are evaluated. For validation, the analytical solutions are compared with the numerical solutions of models using the discontinuous Galerkin finite element method. Results of different case studies are discussed for linear and nonlinear adsorption isotherms. The discontinuous Galerkin method is employed to obtain moments for both linear and nonlinear models numerically. Analytically and numerically determined concentration profiles and moments were found to be in good agreement.

8. Optimization of Orifice Geometry for Cross-Flow Mixing in a Cylindrical Duct

NASA Technical Reports Server (NTRS)

Kroll, J. T.; Sowa, W. A.; Samuelsen, G. S.

1996-01-01

Mixing of gaseous jets in a cross-flow has significant applications in engineering, one example of which is the dilution zone of a gas turbine combustor. Despite years of study, the design of the jet injection in combustors is largely based on practical experience. The emergence of NO(x) regulations for stationary gas turbines and the anticipation of aero-engine regulations requires an improved understanding of jet mixing as new combustor concepts are introduced. For example, the success of the staged combustor to reduce the emission of NO(x) is almost entirely dependent upon the rapid and complete dilution of the rich zone products within the mixing section. It is these mixing challenges to which the present study is directed. A series of experiments was undertaken to delineate the optimal mixer orifice geometry. A cross-flow to core-flow momentum-flux ratio of 40 and a mass flow ratio of 2.5 were selected as representative of a conventional design. An experimental test matrix was designed around three variables: the number of orifices, the orifice length-to- width ratio, and the orifice angle. A regression analysis was performed on the data to arrive at an interpolating equation that predicted the mixing performance of orifice geometry combinations within the range of the test matrix parameters. Results indicate that the best mixing orifice geometry tested involves eight orifices with a long-to-short side aspect ratio of 3.5 at a twenty-three degree inclination from the center-line of the mixing section.

9. CFD Assessment of Orifice Aspect Ratio and Mass Flow Ratio on Jet Mixing in Rectangular Ducts

NASA Technical Reports Server (NTRS)

Bain, D. B.; Smith, C. E.; Holdeman, J. D.

1994-01-01

Isothermal CFD analysis was performed on axially opposed rows of jets mixing with cross flow in a rectangular duct. Laterally, the jets' centerlines were aligned with each other on the top and bottom walls. The focus of this study was to characterize the effects of orifice aspect ratio and jet-to-mainstream mass flow ratio on jet penetration and mixing. Orifice aspect ratios (L/W) of 4-to-1, 2-to-1, and 1-to-1, along with circular holes, were parametrically analyzed. Likewise, jet-to-mainstream mass flow ratios (MR) of 2.0, 0.5, and 0.25 were systematically investigated. The jet-to-mainstream momentum-flux ratio (J) was maintained at 36 for all cases, and the orifice spacing-to-duct height (S/H) was varied until optimum mixing was attained for each configuration. The numerical results showed that orifice aspect ratio (and likewise orifice blockage) had little effect on jet penetration and mixing. Based on mixing characteristics alone, the 4-to-1 slot was comparable to the circular orifice. The 4-to-1 slot has a smaller jet wake which may be advantageous for reducing emissions. However, the axial length of a 4-to-1 slot may be prohibitively long for practical application, especially for MR of 2.0. The jet-to-mainstream mass flow ratio had a more significant effect on jet penetration and mixing. For a 4-to-1 aspect ratio orifice, the design correlating parameter for optimum mixing (C = (S/H)(sq. root J)) varied from 2.25 for a mass flow ratio of 2.0 to 1.5 for a mass flow ratio of 0.25.

10. Performance model for optical extraction from a pulsed chemical oxygen-iodine laser

Copeland, D. A.; Bauer, A. H.; Jones, K. D.

A comprehensive time-dependent gain model for pulsed optical extraction from a flowing oxygen-iodine laser medium is described. Gas flow is treated using an unsteady, premixed, quasi-one-dimensional model which accounts for gas motion and expansion as well as heat release in the cavity. The model uses a simplified, temperature-dependent, chemical kinetics package which consists of several reactions among the 3Sigma, 1Delta, and 1Sigma states of oxygen, atomic and molecular iodine, water, and helium. Hyperfine relaxation effects on the gain and optical extraction from the 3-4 line are treated using a simple four-level laser model. An efficient algorithm for solving the coupled medium and optical extraction equations is described. This gain model, in conjunction with a geometric model of an unstable confocal resonator, is used to examine energy extraction from the medium as a function of pulse repetition rate, duty cycle, and optical mode width. It is shown that the output power may exhibit flow-induced relaxation oscillations and the conditions under which these oscillations occur are discussed.

11. Predicting the threshold of pulse-train electrical stimuli using a stochastic auditory nerve model: the effects of stimulus noise.

PubMed

Xu, Yifang; Collins, Leslie M

2004-04-01

The incorporation of low levels of noise into an electrical stimulus has been shown to improve auditory thresholds in some human subjects (Zeng et al., 2000). In this paper, thresholds for noise-modulated pulse-train stimuli are predicted utilizing a stochastic neural-behavioral model of ensemble fiber responses to bi-phasic stimuli. The neural refractory effect is described using a Markov model for a noise-free pulse-train stimulus and a closed-form solution for the steady-state neural response is provided. For noise-modulated pulse-train stimuli, a recursive method using the conditional probability is utilized to track the neural responses to each successive pulse. A neural spike count rule has been presented for both threshold and intensity discrimination under the assumption that auditory perception occurs via integration over a relatively long time period (Bruce et al., 1999). An alternative approach originates from the hypothesis of the multilook model (Viemeister and Wakefield, 1991), which argues that auditory perception is based on several shorter time integrations and may suggest an NofM model for prediction of pulse-train threshold. This motivates analyzing the neural response to each individual pulse within a pulse train, which is considered to be the brief look. A logarithmic rule is hypothesized for pulse-train threshold. Predictions from the multilook model are shown to match trends in psychophysical data for noise-free stimuli that are not always matched by the long-time integration rule. Theoretical predictions indicate that threshold decreases as noise variance increases. Theoretical models of the neural response to pulse-train stimuli not only reduce calculational overhead but also facilitate utilization of signal detection theory and are easily extended to multichannel psychophysical tasks.

12. Modeling of testosterone regulation by pulse-modulated feedback: An experimental data study

Mattsson, Per; Medvedev, Alexander

2013-10-01

The continuous part of a hybrid (pulse-modulated) model of testosterone feedback regulation is extended with infinite-dimensional and nonlinear dynamics, to better explain the testosterone concentration profiles observed in clinical data. A linear least-squares based optimization algorithm is developed for the purpose of detecting impulses of gonadotropin-realsing hormone from measured concentration of luteinizing hormone. The parameters in the model are estimated from hormone concentration measured in human males, and simulation results from the full closed-loop system are provided.

13. Pulsed Inductive Thruster (PIT): Modeling and Validation Using the MACH2 Code

NASA Technical Reports Server (NTRS)

Schneider, Steven (Technical Monitor); Mikellides, Pavlos G.

2003-01-01

Numerical modeling of the Pulsed Inductive Thruster exercising the magnetohydrodynamics code, MACH2 aims to provide bilateral validation of the thruster's measured performance and the code's capability of capturing the pertinent physical processes. Computed impulse values for helium and argon propellants demonstrate excellent correlation to the experimental data for a range of energy levels and propellant-mass values. The effects of the vacuum tank wall and massinjection scheme were investigated to show trivial changes in the overall performance. An idealized model for these energy levels and propellants deduces that the energy expended to the internal energy modes and plasma dissipation processes is independent of the propellant type, mass, and energy level.

14. Extinction and permanence of two-nutrient and two-microorganism chemostat model with pulsed input

Wang, Tieying; Chen, Lansun; Zhang, Ping

2010-10-01

In this paper, a model of the chemostat involving two species of microorganisms competing for two perfectly complementary, growth-limiting nutrients and periodically pulsed input is considered. By using the Floquet's theorem, we find the two-microorganism eradication periodic solution is globally asymptotically stable if R1 < 1 . At the same time we can find nutrients and microorganisms are permanent if R2 > 1 . Meanwhile, sufficient conditions based on biologically meaningful parameters in the model are given that predict competitive exclusion for certain parameter ranges and coexistence for others. Finally, our results are illustrated by numerical simulation.

15. Nonstationary flow in the model channel of a ramjet engine in pulse-periodic energy supply

Zamuraev, V. P.; Kalinina, A. P.

2008-05-01

A study has been made of the influence of the pulse-periodic supply of energy that is equal to the energy released in the combustion of hydrogen in air on the structure of supersonic flow in a channel of variable cross section, modeling the duct of a ramjet engine. The flow has been modeled on the basis of two-dimensional nonstationary gas-dynamic equations. Different flow regimes have been obtained depending on the configuration of the zones of energy supply and the excess-air coefficients.

16. Intrinsic chirp of attosecond pulses: Single-atom model versus experiment

SciTech Connect

Kazamias, S.; Balcou, Ph.

2004-06-01

We demonstrate and evaluate the importance of an intrinsic chirp inherent to attosecond pulse creation accompanying high-order harmonic generation in recently published experimental data by Dinu et al. [Phys. Rev. Lett. 91, 063901 (2003)]. We present an analytical model, from which the atomic origin of the harmonic chirp is clearly understood. Moreover, the behavior of the chirp as a function of experimental parameters such as laser intensity is inferred. The comparison between our model and the experimental data provides us with useful information about the conditions in which the high-order harmonics is generated.

17. A model for diffusive transport through a spherical interface probed by pulsed-field gradient NMR.

PubMed Central

Price, W S; Barzykin, A V; Hayamizu, K; Tachiya, M

1998-01-01

In biological systems, because of higher intracellular viscosity and/or the restriction of the diffusion space inside cells, the (apparent) diffusion coefficient of an intracellular species (e.g., water) is generally smaller than when it is in the extracellular medium. This difference affects the spin-echo signal attenuation in the pulsed field gradient NMR experiment and thus affords a means of separating the intracellular from the extracellular species, thereby providing a basis for studying transmembrane transport. Such experiments have commonly been analyzed using the macroscopic model of Kärger (see Adv. Magn. Reson. 21:1-89 (1988)). In our previous study, we considered a microscopic model of diffusive transport through a spherical interface using the short gradient pulse approximation (J. Magn. Reson. A114:39-46 (1995)). The spins in the external medium were modeled with the "partially absorbing wall" condition or as having a small but finite lifetime. In the present paper, we extend our treatment to the case in which there is no limitation upon the lifetime in either medium. We also consider a simple modification of Kärger's model that more properly accounts for the restricted intracellular diffusion. Importantly, it was found that the exact solution within the short gradient pulse approximation developed here and the modified Kärger model are in close agreement in the (experimentally relevant) long-time limit. The results of this study show that when there is no limitation upon the lifetime of the transported species in either phase, the spin-echo attenuation curve is very sensitive to transport. PMID:9591653

18. Predictions of psychophysical measurements for sinusoidal amplitude modulated (SAM) pulse-train stimuli from a stochastic model.

PubMed

Xu, Yifang; Collins, Leslie M

2007-08-01

Two approaches have been proposed to reduce the synchrony of the neural response to electrical stimuli in cochlear implants. One approach involves adding noise to the pulse-train stimulus, and the other is based on using a high-rate pulse-train carrier. Hypotheses regarding the efficacy of the two approaches can be tested using computational models of neural responsiveness prior to time-intensive psychophysical studies. In our previous work, we have used such models to examine the effects of noise on several psychophysical measures important to speech recognition. However, to date there has been no parallel analytic solution investigating the neural response to the high-rate pulse-train stimuli and their effect on psychophysical measures. This work investigates the properties of the neural response to high-rate pulse-train stimuli with amplitude modulated envelopes using a stochastic auditory nerve model. The statistics governing the neural response to each pulse are derived using a recursive method. The agreement between the theoretical predictions and model simulations is demonstrated for sinusoidal amplitude modulated (SAM) high rate pulse-train stimuli. With our approach, predicting the neural response in modern implant devices becomes tractable. Psychophysical measurements are also predicted using the stochastic auditory nerve model for SAM high-rate pulse-train stimuli. Changes in dynamic range (DR) and intensity discrimination are compared with that observed for noise-modulated pulse-train stimuli. Modulation frequency discrimination is also studied as a function of stimulus level and pulse rate. Results suggest that high rate carriers may positively impact such psychophysical measures.

19. Neural network modeling of pulsed-laser weld pool shapes in aluminum alloy welds

SciTech Connect

Vitek, J.M.; Iskander, Y.S.; Oblow, E.M.; Babu, S.S.; David, S.A.; Fuerschbach, P.W.; Smartt, H.B.; Pace, D.P. Tolle, C.R.

1998-11-01

A model was developed to predict the weld pool shape in pulsed Nd:YAG laser welds of aluminum alloy 5754. The model utilized neural network analysis to relate the weld process conditions to four pool shape parameters: penetration, width, width at half-penetration, and cross-sectional area. The model development involved the identification of the input (process) variables, the desired output (shape) variables, and the optimal neural network architecture. The latter was influenced by the number of defined inputs and outputs as well as the amount of data that was available for training the network. After appropriate training, the best network was identified and was used to predict the weld shape. A routine to convert the shape parameters into predicted weld profiles was also developed. This routine was based on the actual experimental weld profiles and did not impose an artificial analytical function to describe the weld profile. The neural network model was tested on experimental welds. The model predictions were excellent. It was found that the predicted shapes were within the experimental variations that were found along the length of the welds (due to the pulsed nature of the weld power) and the reproducibility of welds made under nominally identical conditions.

20. Neural network modeling of pulsed-laser weld pool shapes in aluminum alloy welds

SciTech Connect

Vitek, J.M.; Iskander, Y.S.; Oblow, E.M.; Babu, S.S.; David, S.A.; Fuerschbach, P.W.; Smartt, H.B.

1998-09-01

A model was developed to predict the weld pool shape in pulsed Nd:YAG laser welds of aluminum alloy 5754. The model utilized neural network analysis to relate the weld process conditions to four pool shape parameters: (1) penetration width, (2) width at half-penetration, and (3) cross-sectional area. The model development involved the identification of the input (process) variables, the desired output (shape) variables, and the optimal neural network architecture. The latter was influenced by the number of defined inputs and outputs as well as the amount of data that was available for training the network. After appropriate training, die best network was identified and was used to predict the weld shape. A routine to convert the shape parameters into predicted weld profiles was also developed. This routine was based on the actual experimental weld profiles and did not impose an artificial analytical function to describe the weld profile. The neural network model was tested on experimental welds. The model predictions were excellent. It was found that the predicted shapes were within the experimental variations that were found along the length of the welds (due to the pulsed nature of the weld power) and the reproducibility of welds made under nominally identical conditions.

1. Self-healing slip pulses in dynamic rupture models due to velocity-dependent strength

USGS Publications Warehouse

Beeler, N.M.; Tullis, T.E.

1996-01-01

rise time and rupture propagation velocity depend on the choice of constitutive parameters. The second strength function is a natural log velocity-dependent form similar to constitutive laws that fit experimental rock friction data at lower velocities. Slip pulses also arise with this function. For a reasonable choice of constitutive parameters, slip pulses with this function do not propagate at speeds greater than the Raleighwave velocity. The calculated slip pulses are similar in many aspects to seismic observations of short rise time. In all cases of self-healing slip pulses, the residual stress increases with distance behind the trailing edge of the pulse so that the final stress drop is much less than the dynamic stress drop, in agreement with the model of Brune (1976) and some recent seismological observations of rupture.

2. Modeling of Dense Plasma Effects in Short-Pulse Laser Experiments

Walton, Timothy; Golovkin, Igor; Macfarlane, Joseph; Prism Computational Sciences, Madison, WI Team

2016-10-01

Warm and Hot Dense Matter produced in short-pulse laser experiments can be studied with new high resolving power x-ray spectrometers. Data interpretation implies accurate modeling of the early-time heating dynamics and the radiation conditions that are generated. Producing synthetic spectra requires a model that describes the major physical processes that occur inside the target, including the hot-electron generation and relaxation phases and the effect of target heating. An important issue concerns the sensitivity of the predicted K-line shifts to the continuum lowering model that is used. We will present a set of PrismSPECT spectroscopic simulations using various continuum lowering models: Hummer/Mihalas, Stewart-Pyatt, and Ecker-Kroll and discuss their effect on the formation of K-shell features. We will also discuss recently implemented models for dense plasma shifts for H-like, He-like and neutral systems.

3. Kinetic model for the inactivation of Lactobacillus plantarum by pulsed electric fields.

PubMed

Rodrigo, D; Ruíz, P; Barbosa-Cánovas, G V; Martínez, A; Rodrigo, M

2003-03-25

The kinetics of Lactobacillus plantarum inactivation by pulsed electric fields (PEF) was studied in two different growth stages (exponential and stationary), but in the same reference medium (0.6% peptone water). Electric field intensity and treatment time varied from 20 to 28 kV/cm and 30 to 240 micros, respectively. The experimental data showed that cells in the exponential growth stage were more sensitive to PEF treatment than those in the stationary stage. The inactivation data were adjusted to the Bigelow and Hülsheger models and the Weibull frequency distribution function, and constants were calculated for both growth stages in each model. The models were tested and their accuracy was assessed by using the Accuracy Factor. According to this parameter, the Weibull frequency distribution function gave better fittings for the inactivation by PEF than Bigelow or Hülsheger models. On the other hand, the Bigelow model gave a good accuracy factor and is simpler.

4. Air release measurements of V-oil 1404 downstream of a micro orifice at choked flow conditions

Freudigmann, H.-A.; Iben, U.; Pelz, P. F.

2015-12-01

This study presents measurements on air release of V-oil 1404 in the back flow of a micro orifice at choked flow conditions using a shadowgraph imaging method. The released air was determined at three positions downstream of the orifice for different pressure conditions. It was found that more than 23% of the initially dissolved air is released and appears downstream of the orifice in the form of bubbles.

5. Multi-scale modelling of pulsed nanosecond dielectric barrier plasma discharges in plane-to-plane geometry

Nagaraja, Sharath; Yang, Vigor; Adamovich, Igor

2013-04-01

An integrated theoretical and numerical framework is developed to study the dynamics of energy coupling, gas heating and generation of active species by repetitively pulsed nanosecond dielectric barrier discharges (NS DBDs) in air. The work represents one of the first attempts to simulate, in a self-consistent manner, multiple (more than 100) nanosecond pulses. Detailed information is obtained about the electric-field transients during each voltage pulse, and accumulation of plasma generated species and gas heating over ms timescales. The plasma is modelled using a two-temperature, detailed chemistry scheme, with ions and neutral species in thermal equilibrium at the gas temperature, and electrons in thermal nonequilibrium. The analysis is conducted with pressures and pulsing frequency in the range 40-100 Torr and 1-105 Hz, respectively. The input electrical energy is directly proportional to the number density, and remains fairly constant on a per molecule basis from pulse to pulse. Repetitive pulsing results in uniform production of atomic oxygen in the discharge volume via electron-impact dissociation during voltage pulses, and through quenching of excited nitrogen molecules in the afterglow. The ion Joule effect causes rapid gas heating of ˜40 K/pulse in the cathode sheath and generates weak acoustic waves. Conductive heat loss to the walls during the time interval between voltage pulses prevents overheating of the cathode layer and development of ionization instabilities. A uniform ‘hat-shaped’ temperature profile develops in the discharge volume after multiple pulses, due to chemical heat release from quenching of excited species. This finding may explain experimentally observed volumetric ignition (as opposed to hot-spot ignition) in fuel-air mixtures subject to NS DBD.

6. Spectral-spatial fusion model for robust blood pulse waveform extraction in photoplethysmographic imaging.

PubMed

Amelard, Robert; Clausi, David A; Wong, Alexander

2016-12-01

Photoplethysmographic imaging is an optical solution for non-contact cardiovascular monitoring from a distance. This camera-based technology enables physiological monitoring in situations where contact-based devices may be problematic or infeasible, such as ambulatory, sleep, and multi-individual monitoring. However, automatically extracting the blood pulse waveform signal is challenging due to the unknown mixture of relevant (pulsatile) and irrelevant pixels in the scene. Here, we propose a signal fusion framework, FusionPPG, for extracting a blood pulse waveform signal with strong temporal fidelity from a scene without requiring anatomical priors. The extraction problem is posed as a Bayesian least squares fusion problem, and solved using a novel probabilistic pulsatility model that incorporates both physiologically derived spectral and spatial waveform priors to identify pulsatility characteristics in the scene. Evaluation was performed on a 24-participant sample with various ages (9-60 years) and body compositions (fat% 30.0 ± 7.9, muscle% 40.4 ± 5.3, BMI 25.5 ± 5.2 kg·m(-2)). Experimental results show stronger matching to the ground-truth blood pulse waveform signal compared to the FaceMeanPPG (p < 0.001) and DistancePPG (p < 0.001) methods. Heart rates predicted using FusionPPG correlated strongly with ground truth measurements (r(2) = 0.9952). A cardiac arrhythmia was visually identified in FusionPPG's waveform via temporal analysis.

7. Pulsed Bessel-Gauss beams: a depleted wave model for type II second-harmonic generation.

PubMed

2014-11-10

In this work, a three-dimensional and time-dependent nonlinear wave model to describe the generation of pulsed Bessel-Gauss second-harmonic waves (SHWs) is presented. Three coupled equations, two for ordinary and extraordinary fundamental waves and one for extraordinary SHWs, describing type II second-harmonic generation (SHG) in a KTiOPO4 (KTP) crystal were solved by considering the depletion of fundamental waves (FWs). The results examined the validity of nondepleted wave approximation against the energy of pulses, beam spot size, and interaction length. It was shown that for pulses with spot sizes of ωf=80  μm and energy of 0.8j, the nonlinear interaction was accomplished over a distance of ∼5  mm. Therefore, for KTP crystals with lengths longer than 5 mm, the nondepleted wave approximation can no longer be valid. To be valid, the crystal must be shorter than the interaction length, i.e., 5 mm.

8. Spectral-spatial fusion model for robust blood pulse waveform extraction in photoplethysmographic imaging

PubMed Central

Amelard, Robert; Clausi, David A.; Wong, Alexander

2016-01-01

Photoplethysmographic imaging is an optical solution for non-contact cardiovascular monitoring from a distance. This camera-based technology enables physiological monitoring in situations where contact-based devices may be problematic or infeasible, such as ambulatory, sleep, and multi-individual monitoring. However, automatically extracting the blood pulse waveform signal is challenging due to the unknown mixture of relevant (pulsatile) and irrelevant pixels in the scene. Here, we propose a signal fusion framework, FusionPPG, for extracting a blood pulse waveform signal with strong temporal fidelity from a scene without requiring anatomical priors. The extraction problem is posed as a Bayesian least squares fusion problem, and solved using a novel probabilistic pulsatility model that incorporates both physiologically derived spectral and spatial waveform priors to identify pulsatility characteristics in the scene. Evaluation was performed on a 24-participant sample with various ages (9–60 years) and body compositions (fat% 30.0 ± 7.9, muscle% 40.4 ± 5.3, BMI 25.5 ± 5.2 kg·m−2). Experimental results show stronger matching to the ground-truth blood pulse waveform signal compared to the FaceMeanPPG (p < 0.001) and DistancePPG (p < 0.001) methods. Heart rates predicted using FusionPPG correlated strongly with ground truth measurements (r2 = 0.9952). A cardiac arrhythmia was visually identified in FusionPPG’s waveform via temporal analysis. PMID:28018712

9. Apparatus and process for depositing hard coating in a nozzle orifice

DOEpatents

Flynn, P.L.; Giammarise, A.W.

1994-12-20

The present invention is directed to a process for coating the interior surfaces of an orifice in a substrate that forms a slurry fuel injection nozzle. In a specific embodiment, the nozzle is part of a fuel injection system for metering a coal-water slurry into a large, medium-speed, multi-cylinder diesel engine. In order to retard erosion of the orifice, the substrate is placed in a chemical vapor deposition (CVD) reaction chamber. A reaction gas is passed into the chamber at a gas temperature below its reaction temperature and is directed through the orifice in the substrate. The gas reaction temperature is a temperature at and above which the reaction gas deposits as a coating, and the reaction gas is of a composition whereby improved resistance to erosion by flow of the particulates in the slurry fuel is imparted by the deposited coating. Only the portion of the substrate in proximity to the orifice to be coated is selectively heated to at least the gas reaction temperature for effecting coating of the orifice's interior surfaces by the vapor deposited coating formed from the reaction gas. 2 figures.

10. Apparatus and process for depositing hard coating in a nozzle orifice

DOEpatents

Flynn, Paul L.; Giammarise, Anthony W.

1994-01-01

The present invention is directed to a process for coating the interior surfaces of an orifice in a substrate that forms a slurry fuel injection nozzle. In a specific embodiment, the nozzle is part of a fuel injection system for metering a coal-water slurry into a large, medium-speed, multi-cylinder diesel engine. In order to retard erosion of the orifice, the substrate is placed in a chemical vapor deposition (CVD) reaction chamber. A reaction gas is passed into the chamber at a gas temperature below its reaction temperature and is directed through the orifice in the substrate. The gas reaction temperature is a temperature at and above which the reaction gas deposits as a coating, and the reaction gas is of a composition whereby improved resistance to erosion by flow of the particulates in the slurry fuel is imparted by the deposited coating. Only the portion of the substrate in proximity to the orifice to be coated is selectively heated to at least the gas reaction temperature for effecting coating of the orifice's interior surfaces by the vapor deposited coating formed from the reaction gas.

11. Impact of orifice orientation on a finite-span synthetic jet interaction with a crossflow

Van Buren, Tyler; Leong, Chia Min; Whalen, Edward; Amitay, Michael

2016-03-01

The formation and evolution of flow structures associated with a finite-span synthetic jet issued into a zero-pressure gradient boundary layer were investigated experimentally using stereoscopic particle image velocimetry. A synthetic jet with an aspect ratio of AR = 18 was mounted on a flat plate and its interaction with a free stream, having a velocity of U∞ = 10 m/s (Reδ = 2000) at momentum coefficients of Cμ = 0.08, 0.33, and 0.75, was studied. The effect of the orifice pitch (α = 20∘-90∘) and skew (β = 0∘-90∘) angles on vortex formation as well as the global impact of the synthetic jet on the flow field was explored in detail. It was found that the orifice orientation had a significant impact on the steady and unsteady flow structures. Different orifice skew and pitch angles could result in several types of vortical structures downstream, including: no coherent vortex structure, a single (positive or negative) strong vortex, or a symmetric vortex pair. In all cases, the velocity near the wall was increased; however, cases with higher blockage (i.e., more wall-normal, transverse orifice) resulted in a strong velocity deficit in the free stream where orifices with lower pitch angles yielded in an increase in velocity throughout. The analysis is concluded with a summary of quantitative metrics that allude to flow control effectiveness.

12. Natural orifice transluminal endoscopic surgery in urology: Review of the world literature.

PubMed

Bazzi, Wassim M; Raheem, Omer A; Cohen, Seth A; Derweesh, Ithaar H

2012-01-01

Natural orifice transluminal endoscopic surgery (NOTES) has gained momentum in the recent urologic literature as a new surgical approach for intra-abdominal organs with scarless and painless postoperative recoveries. We sought to review the published literature concerning the safety and reproducibility of NOTES in urology. PubMed literature review of articles published in the English language was performed over a 10-year period, i.e., between 2001 and 2011; all articles were critically reviewed and analyzed. Despite its novelty, pure or hybrid surgical approaches have been adapted in performing NOTES. NOTES essentially utilizes transluminal flexible endoscopic instruments along with laparoscopic instruments to gain access to abdominal, pelvic, and/or retroperitoneal cavities. The preliminary results of NOTES in surgery and to a limited extent in urology appear promising, yet further research in animal survival and human cadaveric models is requisite prior to human applications, especially for complex surgeries. Future innovative research, particularly biomedical engineering, should be directed to improving the technicality and mechanistic application of NOTES; hence, better safety and efficacy of NOTES.

13. Inductive pulsed plasma thruster model with time-evolution of energy and state properties

Polzin, K. A.; Sankaran, K.; Ritchie, A. G.; Reneau, J. P.

2013-11-01

A model for pulsed inductive plasma acceleration is presented that consists of a set of circuit equations coupled to both a one-dimensional (1D) equation of motion and an equation governing the partitioning of energy. The latter two equations are obtained for the plasma current sheet by treating it as a single element of finite volume and integrating the governing equations over that volume. The integrated terms are replaced where necessary by physically equivalent approximations that are calculated through the solution of other parts of the governing equation set. The model improves upon previous 1D performance models by permitting the time-evolution of the temperature consistent with the time-varying energy flux into the plasma. The plasma state properties are also more realistically modelled and evolved in time, allowing for the tailoring of the model to different gases that may be chosen as propellants. Computational results for argon propellant are presented to demonstrate the efficacy of the model. The model produces a result where efficiency is maximized at a given value of the electrodynamic scaling term known as the dynamic impedance parameter. The scaling of different energy sinks as a function of the dynamic impedance parameter provides insight into the global energy partitioning in these types of accelerators. Results from the present model deviate from the previous version where temperature is selected as an input without regard for the energy that would be deposited to heat the gas to that temperature. Qualitatively and quantitatively, the model predicts specific impulse values that compare favourably with those measured for two separate inductive pulsed plasma thrusters. Efficiency is underpredicted in the regime where data are available, but the trends in the data and simulations follow similar trajectories that appear to be converging towards a predicted peak efficiency as the dynamic impedance parameter is increased.

14. Modeling high-intensity pulsed electric field inactivation of a lipase from Pseudomonas fluorescens.

PubMed

Soliva-Fortuny, R; Bendicho-Porta, S; Martín-Belloso, O

2006-11-01

The inactivation kinetics of a lipase from Pseudomonas fluorescens (EC 3.1.1.3.) were studied in a simulated skim milk ultrafiltrate treated with high-intensity pulsed electric fields. Samples were subjected to electric field intensities ranging from 16.4 to 27.4 kV/cm for up to 314.5 micros, thus achieving a maximum inactivation of 62.1%. The suitability of describing experimental data using mechanistic first-order kinetics and an empirical model based on the Weibull distribution function is discussed. In addition, different mathematical expressions relating the residual activity values to field strength and treatment time are supplied. A first-order fractional conversion model predicted residual activity with good accuracy (A(f) = 1.018). A mechanistic insight of the model kinetics was that experimental values were the consequence of different structural organizations of the enzyme, with uneven resistance to the pulsed electric field treatments. The Weibull model was also useful in predicting the energy density necessary to achieve lipase inactivation.

15. Modeling the absorption of intense, short laser pulses in steep density gradients

SciTech Connect

Alley, W.E.

1991-01-28

A subroutine which calculates the absorption of short pulse electromagnetic radiation in a material has been installed into the laser fusion modeling program called LASNEX. Calculational results show the necessity for NLTE physics to account for ionization, the development of non-exponential density profiles for the expanding plasma and movement of the critical point toward the surface which results in Doppler shifts of the reflected light. Comparison of calculations of local scale lengths with experiments shows not only good agreement but the correct scaling with intensity. 8 refs., 5 figs.

16. A nonlinear dynamical system for combustion instability in a pulse model combustor

Takagi, Kazushi; Gotoda, Hiroshi

2016-11-01

We theoretically and numerically study the bifurcation phenomena of nonlinear dynamical system describing combustion instability in a pulse model combustor on the basis of dynamical system theory and complex network theory. The dynamical behavior of pressure fluctuations undergoes a significant transition from steady-state to deterministic chaos via the period-doubling cascade process known as Feigenbaum scenario with decreasing the characteristic flow time. Recurrence plots and recurrence networks analysis we adopted in this study can quantify the significant changes in dynamic behavior of combustion instability that cannot be captured in the bifurcation diagram.

17. Influence of Local Flow Field on Flow Accelerated Corrosion Downstream from an Orifice

Utanohara, Yoichi; Nagaya, Yukinori; Nakamura, Akira; Murase, Michio

Flow accelerated corrosion (FAC) rate downstream from an orifice was measured in a high-temperature water test loop to evaluate the effects of flow field on FAC. Orifice flow was also measured using laser Doppler velocimetry (LDV) and simulated by steady RANS simulation and large eddy simulation (LES). The LDV measurements indicated the flow structure did not depend on the flow velocity in the range of Re = 2.3×104 to 1.2×105. Flow fields predicted by RANS and LES agreed well with LDV data. Measured FAC rate was higher downstream than upstream from the orifice and the maximum appeared at 2D (D: pipe diameter) downstream. The shape of the profile of the root mean square (RMS) wall shear stress predicted by LES had relatively good agreement with the shape of the profile of FAC rate. This result indicates that the effects of flow field on FAC can be evaluated using the calculated wall shear stress.

18. Visual study of the effect of grazing flow on the oscillatory flow in a resonator orifice

NASA Technical Reports Server (NTRS)

Baumeister, K. J.; Rice, E. J.

1975-01-01

Grazing flow and oscillatory flow in an orifice were studied in a plexiglass flow channel with a single side branch Helmholtz resonator using water as the fluid medium. An oscillatory flow was applied to the resonatory cavity, and color dyes were injected in both the orifice and the grazing flow field to record the motion of the fluid. The flow regimes associated with linear and nonlinear (high sound pressure level) impedances with and without grazing flows were recorded by a high-speed motion-picture camera. Appreciable differences in the oscillatory flow field were seen in the various flow regimes. With high grazing flows, the outflow and inflow from the resonator cavity are found to be asymmetric. The visual study confirms that jet energy loss during flow into a resonator cavity is much larger than the loss for ejection from the cavity into the grazing flow. For inflow into the resonator cavity, the effective orifice area was significantly reduced.

19. Effect of flow rate of side-type orifice intake on withdrawn water temperature.

PubMed

Gao, Xueping; Li, Guangning; Han, Yunpeng

2014-01-01

Side-type orifice intake is a type of selective withdrawal facility used in managing reservoirs to mitigate the negative effects of low-temperature water. Based on the temperature data of a thermal stratified reservoir in China, an experiment was conducted in flume to study the influence of intake flow rate on withdrawn water temperature with different temperature distributions. Results indicated that withdrawn water temperature changed with different flow rates. The temperature change was determined by the water temperature gradients above and below the intake, whereas the change trend of temperature depended on the difference between the water temperature gradient above and below the intake. We likewise proposed a new equation with which the withdrawn water temperature of a thermal stratified reservoir using a side-type orifice could be calculated. These findings could be directly applied to the design and operation of side-type orifice intake in thermal stratified reservoirs.

20. New insights on the propagation of pulsed atmospheric plasma streams: From single jet to multi jet arrays

SciTech Connect

Robert, E.; Darny, T.; Dozias, S.; Iseni, S.; Pouvesle, J. M.

2015-12-15

Atmospheric pressure plasma propagation inside long dielectric tubes is analyzed for the first time through nonintrusive and nonperturbative time resolved bi-directional electric field (EF) measurements. This study unveils that plasma propagation occurs in a region where longitudinal EF exists ahead the ionization front position usually revealed from plasma emission with ICCD measurement. The ionization front propagation induces the sudden rise of a radial EF component. Both of these EF components have an amplitude of several kV/cm for helium or neon plasmas and are preserved almost constant along a few tens of cm inside a capillary. All these experimental measurements are in excellent agreement with previous model calculations. The key roles of the voltage pulse polarity and of the target nature on the helium flow patterns when plasma jet is emerging in ambient air are documented from Schlieren visualization. The second part of this work is then dedicated to the development of multi jet systems, using two different setups, based on a single plasma source. Plasma splitting in dielectric tubes drilled with sub millimetric orifices, but also plasma transfer across metallic tubes equipped with such orifices are reported and analyzed from ICCD imaging and time resolved EF measurements. This allows for the design and the feasibility validation of plasma jet arrays but also emphasizes the necessity to account for voltage pulse polarity, target potential status, consecutive helium flow modulation, and electrostatic influence between the produced secondary jets.

1. Analysis of dc harmonics using the three-pulse model for the intermountain power project HVDC transmission

SciTech Connect

Dickmander, D.L.; Peterson, K.J.

1989-04-01

The harmonic analysis of the dc-side of an HVDC line transmission requires realistic models of the converters, the dc line, and other relevant equipment. These models must include all important paths for harmonic current, and appropriate sources of harmonic voltage generation. The classical converter modeling technique has been demonstrated to be insufficient in field measurements and analysis of the harmonic spectra found on recent HVDC line transmission. For this reason, a new model of the converter bridge which takes into account the major stray capacitances in the converter (the three-pulse model) has been developed, and is described in detail elsewhere. This paper presents comparisons between the classical and three-pulse calculations for the Intermountain Power Project (IPP) HVDC transmission. The calculation results from the three-pulse model agree favorably with the harmonics found in field measurements.

2. MATLAB/Simulink Pulse-Echo Ultrasound System Simulator Based on Experimentally Validated Models.

PubMed

Kim, Taehoon; Shin, Sangmin; Lee, Hyongmin; Lee, Hyunsook; Kim, Heewon; Shin, Eunhee; Kim, Suhwan

2016-02-01

A flexible clinical ultrasound system must operate with different transducers, which have characteristic impulse responses and widely varying impedances. The impulse response determines the shape of the high-voltage pulse that is transmitted and the specifications of the front-end electronics that receive the echo; the impedance determines the specification of the matching network through which the transducer is connected. System-level optimization of these subsystems requires accurate modeling of pulse-echo (two-way) response, which in turn demands a unified simulation of the ultrasonics and electronics. In this paper, this is realized by combining MATLAB/Simulink models of the high-voltage transmitter, the transmission interface, the acoustic subsystem which includes wave propagation and reflection, the receiving interface, and the front-end receiver. To demonstrate the effectiveness of our simulator, the models are experimentally validated by comparing the simulation results with the measured data from a commercial ultrasound system. This simulator could be used to quickly provide system-level feedback for an optimized tuning of electronic design parameters.

3. A Three-Pulse Release Tablet for Amoxicillin: Preparation, Pharmacokinetic Study and Physiologically Based Pharmacokinetic Modeling

PubMed Central

Li, Jin; Chai, Hongyu; Li, Yang; Chai, Xuyu; Zhao, Yan; Zhao, Yunfan; Tao, Tao; Xiang, Xiaoqiang

2016-01-01

Background Amoxicillin is a commonly used antibiotic which has a short half-life in human. The frequent administration of amoxicillin is often required to keep the plasma drug level in an effective range. The short dosing interval of amoxicillin could also cause some side effects and drug resistance, and impair its therapeutic efficacy and patients’ compliance. Therefore, a three-pulse release tablet of amoxicillin is desired to generate sustained release in vivo, and thus to avoid the above mentioned disadvantages. Methods The pulsatile release tablet consists of three pulsatile components: one immediate-release granule and two delayed release pellets, all containing amoxicillin. The preparation of a pulsatile release tablet of amoxicillin mainly includes wet granulation craft, extrusion/spheronization craft, pellet coating craft, mixing craft, tablet compression craft and film coating craft. Box–Behnken design, Scanning Electron Microscope and in vitro drug release test were used to help the optimization of formulations. A crossover pharmacokinetic study was performed to compare the pharmacokinetic profile of our in-house pulsatile tablet with that of commercial immediate release tablet. The pharmacokinetic profile of this pulse formulation was simulated by physiologically based pharmacokinetic (PBPK) model with the help of Simcyp®. Results and Discussion Single factor experiments identify four important factors of the formulation, namely, coating weight of Eudragit L30 D-55 (X1), coating weight of AQOAT AS-HF (X2), the extrusion screen aperture (X3) and compression forces (X4). The interrelations of the four factors were uncovered by a Box–Behnken design to help to determine the optimal formulation. The immediate-release granule, two delayed release pellets, together with other excipients, namely, Avicel PH 102, colloidal silicon dioxide, polyplasdone and magnesium stearate were mixed, and compressed into tablets, which was subsequently coated with Opadry

4. Challenging mitral valve repair for double-orifice mitral valve with noncompaction of left ventricular myocardium.

PubMed

Yamasaki, Manabu; Misumi, Hiroyasu; Abe, Kohei; Kawazoe, Kohei

2017-02-25

Double-orifice mitral valve (DOMV) is a relatively rare cardiac anomaly. Although usually associated with various cardiac anomalies, co-presence of DOMV and noncompaction of left ventricular myocardium (NCLVM) is extremely rare. Here, we present a 24-year-old male who underwent mitral valve repair using artificial chordae and annuloplasty at the posterior commissure for severe mitral regurgitation (MR), resulting from flail anterior leaflet of the larger postero-medial orifice and dilatation of left ventricle with NCLVM. One year later, he underwent second mitral valve repair for recurrence of MR. Further endoscopic evaluation of the left ventricle, and reinforcement via artificial ring, enabled us to achieve repair.

5. A comparative study on continuous and pulsed RF argon capacitive glow discharges at low pressure by fluid modeling

Liu, Ruiqiang; Liu, Yue; Jia, Wenzhu; Zhou, Yanwen

2017-01-01

Based on the plasma fluid theory and using the drift-diffusion approximation, a mathematical model for continuous and pulsed radial frequency (RF) argon capacitive glow discharges at low pressure is established. The model is solved by a finite difference method and the numerical results are reported. Based on the systematic analysis of the results, plasma characteristics of the continuous and pulsed RF discharges are comparatively investigated. It is shown that, under the same condition for the peak value of the driving potential, the cycle-averaged electron density, the current density, and other essential physical quantities in the continuous RF discharge are higher than those from the pulsed RF discharge. On the other hand, similar plasma characteristics are obtained with two types of discharges, by assuming the same deposited power. Consequently, higher driving potential is needed in pulsed discharges in order to maintain the same effective plasma current. Furthermore, it is shown that, in the bulk plasma region, the peak value of the bipolar electric field from the continuous RF discharge is greater than that from the pulsed RF discharge. In the sheath region, the ionization rate has the shape of double-peaking and the explanation is given. Because the plasma input power depends on the driving potential and the plasma current phase, the phase differences between the driving potential and the plasma current are compared between the continuous and the pulsed RF discharges. It is found that this phase difference is smaller in the pulsed RF discharge compared to that of the continuous RF discharge. This means that the input energy coupling in the pulsed RF discharge is less efficient than the continuous counterpart. This comparative study, carried out also under other conditions, thus can provide instructive ideas in applications using the continuous and pulsed RF capacitive glow discharges.

6. co2amp: A software program for modeling the dynamics of ultrashort pulses in optical systems with CO2 amplifiers

DOE PAGES

Polyanskiy, Mikhail N.

2015-01-01

We describe a computer code for simulating the amplification of ultrashort mid-infrared laser pulses in CO2 amplifiers and their propagation through arbitrary optical systems. This code is based on a comprehensive model that includes an accurate consideration of the CO2 active medium and a physical optics propagation algorithm, and takes into account the interaction of the laser pulse with the material of the optical elements. Finally, the application of the code for optimizing an isotopic regenerative amplifier is described.

7. Thermal and damage data from multiple microsecond pulse trains at 532nm in an in vitro retinal model

Denton, Michael L.; Tijerina, Amanda J.; Hoffman, Aaron; Clark, Clifton D.; Noojin, Gary D.; Rickman, John M.; Castellanos, Cherry C.; Shingledecker, Aurora D.; Boukhris, Sarah J.; Thomas, Robert J.; Rockwell, Benjamin A.

2014-03-01

An artificially pigmented retinal pigment epithelial (RPE) cell model was used to study the damage rates for exposure to 1, 10, 100, and 1,000 230-μs laser pulses at 532 nm, at two different concentrations of melanosome particles (MPs) per cell. Multiple pulses were delivered at pulse repetition rates of 50 and 99 pulses per second. Standard fluorescence viability indicator dyes and the method of microthermography were used to assess damage and thermal responses, respectively. Although frame rate during microthermography was more than five times slower than the duration of laser pulses, thermal information was useful in refining the BTEC computational model for simulating high-resolution thermal responses by the pigmented cells. When we temporally sampled the thermal model output at a rate similar to our microthermography, the resulting thermal profiles for multiple pulses resembled the thermal experimental profiles. Complementary to the thermal simulations, our computer-generated thresholds were in good agreement with the in vitro data. Findings are examined within the context of common exposure limit definitions in the national and international laser safety standards.

8. 2D positive streamer modelling in NTP air under extreme pulse fronts. What about runaway electrons?

Marode, E.; Dessante, Ph; Tardiveau, P.

2016-12-01

Using a 2D model, an attempt is made to understand the properties and aspects of a diffuse discharge, appearing in a positive point-to-plane gap submitted to very high voltage pulses. After presenting the model, comparisons between the computed low and high pulse heights of 10 kV and 50 kV, respectively, will be shown and analysed. A streamer ionising wave is still formed, but its role in ionising a region of low field is replaced by the role of providing a plasma within which the electrons will benefit from the presence of a high electrical field meant to induce strong electron collision activities. A comparison between the aspect of the computed and experimental discharge carried out in the same conditions at 50 kV will be presented, which seems to be in agreement with the diffuse aspect. Although the difference in order of magnitude of the speed of development and the height of the current must be underlined, similarities between the structures of both situations will, however, be recognised. A high probability of obtaining highly energetic electrons and runaways (RAEs) will also be derived following a simple approach.

9. The removal of Direct Orange 39 by pulsed corona discharge from model wastewater.

PubMed

Vujevic, D; Koprivanac, N; Bozic, A Loncaric; Locke, B R

2004-07-01

Untreated wastewater from the dye industry and dyehouses cannot be directly discharged into the environment due to the high content of organic matter and intensive colouration, even with low concentrations of dye. In this paper, the application of a high voltage pulsed electrical discharge in the aqueous phase has been assessed for the dye degradation. Experiments were conducted in a batch reactor using model wastewater of the commercial water-soluble monoazo dye C.I. Direct Orange 39 (DO39). The effects of zeolite and ferrous sulphate in combination with the corona discharge were examined. Experiments were conducted for a range of process parameters including pH, conductivity, type and amount of zeolite, and ferrous sulphate concentration. A mathematical model to describe the kinetics of DO39 degradation in the corona reactor was developed. Aqueous phase pulsed streamer corona discharge as a method for coloured wastewater treatment showed very high effectiveness in the case of iron salt addition (Fenton's reaction). Low pH enhanced dye removal by corona in the absence of zeolite, thus implying that the acid properties of zeolites are important in dye degradation. Ecological parameters such as COD, TC, IC, TOC and IC50 measured before and after corona treatment showed that the treated wastewater can be discharged into the environment or reused as process water.

10. Prediction of Bubble Diameter at Detachment from a Wall Orifice in Liquid Cross Flow Under Reduced and Normal Gravity Conditions

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Kamotani, Y.

2003-01-01

Bubble formation and detachment is an integral part of the two-phase flow science. The objective of the present work is to theoretically investigate the effects of liquid cross-flow velocity, gas flow rate embodied in the momentum flux force, and orifice diameter on bubble formation in a wall-bubble injection configuration. A two-dimensional one-stage theoretical model based on a global force balance on the bubble evolving from a wall orifice in a cross liquid flow is presented in this work. In this model, relevant forces acting on the evolving bubble are expressed in terms of the bubble center of mass coordinates and solved simultaneously. Relevant forces in low gravity included the momentum flux, shear-lift, surface tension, drag and inertia forces. Under normal gravity conditions, the buoyancy force, which is dominant under such conditions, can be added to the force balance. Two detachment criteria were applicable depending on the gas to liquid momentum force ratio. For low ratios, the time when the bubble acceleration in the direction of the detachment angle is greater or equal to zero is calculated from the bubble x and y coordinates. This time is taken as the time at which all the detaching forces that are acting on the bubble are greater or equal to the attaching forces. For high gas to liquid momentum force ratios, the time at which the y coordinate less the bubble radius equals zero is calculated. The bubble diameter is evaluated at this time as the diameter at detachment from the fact that the bubble volume is simply given by the product of the gas flow rate and time elapsed. Comparison of the model s predictions was also made with predictions from a two-dimensional normal gravity model based on Kumar-Kuloor formulation and such a comparison is presented in this work.

11. Evaluating the use of a continuous approximation for model-based quantification of pulsed chemical exchange saturation transfer (CEST)

PubMed Central

Tee, Y.K.; Khrapitchev, A.A.; Sibson, N.R.; Payne, S.J.; Chappell, M.A.

2012-01-01

Many potential clinical applications of chemical exchange saturation transfer (CEST) have been studied in recent years. However, due to various limitations such as specific absorption rate guidelines and scanner hardware constraints, most of the proposed applications have yet to be translated into routine diagnostic tools. Currently, pulsed CEST which uses multiple short pulses to perform the saturation is the only viable irradiation scheme for clinical translation. However, performing quantitative model-based analysis on pulsed CEST is time consuming because it is necessary to account for the time dependent amplitude of the saturation pulses. As a result, pulsed CEST is generally treated as continuous CEST by finding its equivalent average field or power. Nevertheless, theoretical analysis and simulations reveal that the resulting magnetization is different when the different irradiation schemes are applied. In this study, the quantification of important model parameters such as the amine proton exchange rate from a pulsed CEST experiment using quantitative model-based analyses were examined. Two model-based approaches were considered – discretized and continuous approximation to the time dependent RF irradiation pulses. The results showed that the discretized method was able to fit the experimental data substantially better than its continuous counterpart, but the smaller fitted error of the former did not translate to significantly better fit for the important model parameters. For quantification of the endogenous CEST effect, such as in amide proton transfer imaging, a model-based approach using the average power equivalent saturation can thus be used in place of the discretized approximation. PMID:22858666

12. Effect of Intra-Orifice Depth on Sealing Ability of Four Materials in the Orifices of Root-Filled Teeth: An Ex-Vivo Study

PubMed Central

2012-01-01

Aim. To investigate the effect of orifice cavity depth on the sealing ability of Fusio, Fuji II, Fuji IX, and MTA“G”. Materials and Methods. Ninety-two canals in extracted mandibular premolars were prepared, obturated, and randomly grouped into 4 groups. Each group was subgrouped for a 2 mm and 3 mm orifice cavity depth (n = 10). The remaining roots were divided to serve as positive and negative controls (n = 6). Cavities of the 4 experimental groups were filled with the respective materials and subjected to methylene blue dye leakage. Linear leakage was measured in mm using a stereomicroscope. Statistical Analysis. Kruskall-Wallis test was used at P < 0.05, and t-test was done to compare 2 mm and 3 mm. Results. All tested materials leaked to various degrees. Significantly higher leakage score was found for Fuji IX, Fusio, Fuji II, and MTA “G” in a descending order, when the materials were placed at 3 mm depths. A significant difference was found in the leakage score between the 2 mm and 3 mm depths in all tested materials with the 3 mm depth showing a greater leakage score in all tested materials. Exception was in MTA “G” at 2 mm and 3 mm depths (0.551 mm ± 0.004 mm and 0.308 mm ± 0.08 mm, resp.). Conclusion. The null hypothesis should be partially rejected. Fusio and MTA “G” were affected by orifice cavity depth with regard to their sealing ability. MTA “G” had the least leakage when placed at 2 or 3 mm depths, and Fusio is the next when placed at 2 mm depth. Two millimeters orifice cavity depth is suitable for most adhesive orifice barrier materials. PMID:22675356

13. Requirements for Vertically Installed Runoff Control Boards for the “Paddy Field Dam” and Appropriate Orifice Shapes

Natsuki, Yoshikawa; Hideyuki, Koide; Shin-Ichi, Misawa

While the “Paddy Field Dam” project has been recognized as an effective flood control measure, there are some cases in which the runoff control boards are vertically installed on the opening of the drainage boxes without careful consideration of the orifice shape and size. The important criteria for the runoff control boards to be satisfied are: 1. to maintain a sufficient peak runoff control function, 2. to avoid excessive ponding causing overflow, 3. to minimize the influence to the ordinary water management, and 4. to reserve sufficient orifice area to avoid blockage of the orifice with floating litters. The purpose of this study is to examine proper shapes and sizes of the orifice to satisfy the criteria for the vertically installed runoff control boards through experiments and simulations. Given the condition that the orifice has sufficient area to avoid overflow with 10 and 20 year return period rainfall event (criteria 2), the simulation results show that the orifice with horizontally wider shapes has advantages over the square or circular shapes in terms of the criteria 1 and 3. The disadvantage of the horizontally wider shapes is the blockage of the orifice with floating litters (criteria 4). In conclusion, we proposed to secure sufficient vertical distance to avoid this problem by setting a lower limit on the vertical distance and then determine the widest horizontal distance to optimize all the criteria. In addition, we have constructed the “Orifice Design Assist Tool” on the basis of the examinations in this study.

14. Modeling and calibration of pulse-modulation based ToF imaging systems

Süss, Andreas; Varga, Gabor; Marx, Michael; Fürst, Peter; Gläsener, Stefan; Tiedke, Wolfram; Jung, Melanie; Spickermann, Andreas; Hosticka, Bedrich J.

2016-03-01

Conversely to the continuous wave indirect time-of-flight (CW-iToF) imaging scheme, pulsed modulation ToF (PM-iToF) imaging is a promising depth measurement technique for operation at high ambient illumination. It is known that non-linearity and finite charge-transfer speed impact trueness and precision of ToF systems.1-3 As pulses are no Eigenfunctions to the shutter system, this issue is especially pronounced in pulsed modulation.2, 3 Despite these effects, it is possible to find analytical expressions founded on physical observations that map scenery parameters such as depth information, reflectance and ambient light level to sensor output.3, 4 In the application, the inverse of this map has to be evaluated. In PM-iToF, an inverse function cannot be yielded in a direct manner, as models proposed in the literature were transcendental.3, 4 For a limited range an approximating linearization can be performed to yield depth information.5 To extend the usable range, recently, an alternative approach that indirectly approximates the inverse function was presented.6 This method was founded on 1D doping concentration profiles, which, however, are typically not made available to end users. Also, limitations of the 1D approximation as well as stability are yet to be explored. This work presents a calibration methodology that copes with detector insufficiencies such as finite charge transfer speed. Contrarily to the state of the art, no prior knowledge on details of the underlying devices is required. The work covers measurement setup, a benchmark of various calibration schemes and deals with issues such as overfitting or defect pixels.

15. Incorporation of an Energy Equation into a Pulsed Inductive Thruster Performance Model

NASA Technical Reports Server (NTRS)

Polzin, Kurt A.; Reneau, Jarred P.; Sankaran, Kameshwaran

2011-01-01

A model for pulsed inductive plasma acceleration containing an energy equation to account for the various sources and sinks in such devices is presented. The model consists of a set of circuit equations coupled to an equation of motion and energy equation for the plasma. The latter two equations are obtained for the plasma current sheet by treating it as a one-element finite volume, integrating the equations over that volume, and then matching known terms or quantities already calculated in the model to the resulting current sheet-averaged terms in the equations. Calculations showing the time-evolution of the various sources and sinks in the system are presented to demonstrate the efficacy of the model, with two separate resistivity models employed to show an example of how the plasma transport properties can affect the calculation. While neither resistivity model is fully accurate, the demonstration shows that it is possible within this modeling framework to time-accurately update various plasma parameters.

16. Applicability of the polynomial chaos expansion method for personalization of a cardiovascular pulse wave propagation model.

PubMed

Huberts, W; Donders, W P; Delhaas, T; van de Vosse, F N

2014-12-01

Patient-specific modeling requires model personalization, which can be achieved in an efficient manner by parameter fixing and parameter prioritization. An efficient variance-based method is using generalized polynomial chaos expansion (gPCE), but it has not been applied in the context of model personalization, nor has it ever been compared with standard variance-based methods for models with many parameters. In this work, we apply the gPCE method to a previously reported pulse wave propagation model and compare the conclusions for model personalization with that of a reference analysis performed with Saltelli's efficient Monte Carlo method. We furthermore differentiate two approaches for obtaining the expansion coefficients: one based on spectral projection (gPCE-P) and one based on least squares regression (gPCE-R). It was found that in general the gPCE yields similar conclusions as the reference analysis but at much lower cost, as long as the polynomial metamodel does not contain unnecessary high order terms. Furthermore, the gPCE-R approach generally yielded better results than gPCE-P. The weak performance of the gPCE-P can be attributed to the assessment of the expansion coefficients using the Smolyak algorithm, which might be hampered by the high number of model parameters and/or by possible non-smoothness in the output space.

17. Intensity-Duration Relation in the Bartlett-Lewis Rectangular Pulse Model

Ritschel, Christoph; Rust, Henning; Ulbrich, Uwe; Névir, Peter

2015-04-01

For several hydrological modelling tasks precipitation time series with a high (sub-daily) resolution are indispensable. This data is, however, not always available and thus replaced by model data. A canonical class of stochastic models for sub-daily precipitation is the class of Poisson cluster processes, e.g. the Bartlett-Lewis rectangular pulse model (BLRPM). The BLRPM has been shown to be able to well reproduce certain characteristics found in observations. Our focus is on intensity-duration relationship which are of particular importance in the context of hydrological modelling. We analyse several high resolution precipitation time series (5min) from Berlin and derive empirical intensity-duration relations for several return levels of intensities (intensity-duration-frequency curves, IDF curves). In a second step, we investigate to what extend the variants of a BLRPM are able to reproduce these relations (i.e., the IDF curves) for different situations (e.g., seasons) and for the various return-levels of intensities. By means of a sensitivity study with the BLRPM, we investigate to what extend the ability to reproduce the intensity-duration relationships is related to certain relations between the model parameters. Such relations are typically useful to reduce the complexity of the model and thus robustify and facilitate parameter estimation.

18. Jitter model and signal processing techniques for pulse width modulation optical recording

NASA Technical Reports Server (NTRS)

Liu, Max M.-K.

1991-01-01

A jitter model and signal processing techniques are discussed for data recovery in Pulse Width Modulation (PWM) optical recording. In PWM, information is stored through modulating sizes of sequential marks alternating in magnetic polarization or in material structure. Jitter, defined as the deviation from the original mark size in the time domain, will result in error detection if it is excessively large. A new approach is taken in data recovery by first using a high speed counter clock to convert time marks to amplitude marks, and signal processing techniques are used to minimize jitter according to the jitter model. The signal processing techniques include motor speed and intersymbol interference equalization, differential and additive detection, and differential and additive modulation.

19. Development of Unsteady Aerodynamic State-Space Models from CFD-Based Pulse Responses

NASA Technical Reports Server (NTRS)

Silva, Walter A.; Raveh, Daniella E.

2001-01-01

A method for computing discrete-time state-space models of linearized unsteady aerodynamic behavior directly from aeroelastic CFD codes is presented. The method involves the treatment of CFD-based pulse responses as Markov parameters for use in a system identification /realization algorithm. Results are presented for the AGARD 445.6 Aeroelastic Wing with four aeroelastic modes at a Mach number of 0.96 using the EZNSS Euler/Navier-Stokes flow solver with aeroelastic capability. The System/Observer/Controller Identification Toolbox (SOCIT) algorithm, based on the Ho-Kalman realization algorithm, is used to generate 15th- and 32nd-order discrete-time state-space models of the unsteady aerodynamic response of the wing over the entire frequency range of interest.

20. Model of defect reactions and the influence of clustering in pulse-neutron-irradiated Si

SciTech Connect

Myers, S. M.; Cooper, P. J.; Wampler, W. R.

2008-08-15

Transient reactions among irradiation defects, dopants, impurities, and carriers in pulse-neutron-irradiated Si were modeled taking into account the clustering of the primal defects in recoil cascades. Continuum equations describing the diffusion, field drift, and reactions of relevant species were numerically solved for a submicrometer spherical volume, within which the starting radial distributions of defects could be varied in accord with the degree of clustering. The radial profiles corresponding to neutron irradiation were chosen through pair-correlation-function analysis of vacancy and interstitial distributions obtained from the binary-collision code MARLOWE, using a spectrum of primary recoil energies computed for a fast-burst fission reactor. Model predictions of transient behavior were compared with a variety of experimental results from irradiated bulk Si, solar cells, and bipolar-junction transistors. The influence of defect clustering during neutron bombardment was further distinguished through contrast with electron irradiation, where the primal point defects are more uniformly dispersed.

1. Neural Network Modeling of Weld Pool Shape in Pulsed-Laser Aluminum Welds

SciTech Connect

Iskander, Y.S.; Oblow, E.M.; Vitek, J.M.

1998-11-16

A neural network model was developed to predict the weld pool shape for pulsed-laser aluminum welds. Several different network architectures were examined and the optimum architecture was identified. The neural network was then trained and, in spite of the small size of the training data set, the network accurately predicted the weld pool shape profiles. The neural network output was in the form of four weld pool shape parameters (depth, width, half-width, and area) and these were converted into predicted weld pool profiles with the use of the actual experimental poo1 profiles as templates. It was also shown that the neural network model could reliably predict the change from conduction-mode type shapes to keyhole-mode shapes.

2. Oscillating dome at Santiaguito? A numerical model to explain inter-eruptive pulses

Scharff, L.; Hasenclever, J.; Hort, M. K.

2009-12-01

Volcanic eruption models very well explain eruptive cycles in dome extrusion and repeated explosive degassing. Some models focus on the interaction between crystallisation, conduit geometry, magma degassing, bubble content, and fragmentation. Others explore the dynamics of plug extrusion depending on wall friction, magma influx and plug erosion. But none of these models can explain secondary pulses, i.e. several explosions during one event which is for example observed at Santiaguito volcano, Guatemala. Here we present a numerical model inspired by Doppler radar observations recorded between Jan. 8-13, 2007 during a multidisciplinary experiment at Santiaguito volcano, Guatemala. During the observational period 157 eruptions were observed by Doppler radar. Most of the eruptions were ring-type eruptions starting at the dome center and propagating toward an outer ring (200m in diameter). The very first indication of a starting eruption is a strong signal at very low velocities (<0.8m/s vertical), indicating a slow uplift of the dome. Up to 3s later higher velocities (~60m/s vertical) indicate the onset of an explosion. Johnson et al. (2008) assume that an impermeable carapace is lifted and detached from the ground by gas influx, thereby opening pathways for explosive degassing. But 75% of the explosive degassing events comprise more than one degassing pulse with a typical recurrence period of 3s. The occurrence of pulses during one event has been suggested from thermal imaging of the plume (Sahetapy-Engel et al., 2009), but it was so far unknown and first resolved using a Doppler radar during the experiment mentioned above that these pulses occur almost periodically and originate rather from the dome’s surface than from turbulent jet flow. Based on the model by Johnson et al, we assume that below the impermeable carapace material is continuously fed through the conduit. Uprising magma degasses thereby increasing its gas mass fraction with height in the conduit. This

3. Direct Numerical Simulation of Turbulent Heat Transfer Behind a Rectangular Orifice

Makino, Soihiro; Iwamoto, Kaoru; Kawamura, Hiroshi

Direct numerical simulation of turbulent heat transfer with a rectangular orifice has been performed for Reτ0(=uτ0δ⁄ν) = 300, where uτ0 is the friction velocity calculated from the mean pressure gradient imposed to drive the flow, δ the channel half width and ν the kinematic viscosity. The Prandtl number is 0.71. The ratio of slit height to channel height is assumed to be β=0.3,0.4,0.5,0.6 and 0.7. For β=0.3-0.6, the mean flow becomes asymmetric in the wall-normal direction by the Coanda effect behind the orifice. In the case of β=0.7, however, the mean flow is symmetry. The Nusselt number profiles over the bottom and top walls are different significantly for the asymmetric cases. Large-scale Kelvin-Helmholtz(K-H) vortices are generated at the orifice edges. An entrainment process is observed in the temperature field around these vortices. Subsequently, these K-H vortices become deformed and break up into disordered small-scale structures in the shear layers behind the orifice. In this scenario, the turbulent transport is promoted in the temperature field. In addition, the separation, the reattachment and also the contraction effects are discussed on the profiles of the mean temperature, the temperature variance and the turbulent heat fluxes.

4. Experimental study on the performance of an inverter heat pump system with bypass orifices

SciTech Connect

Choi, J.; Kim, Y.

1999-07-01

An experimental study was performed to investigate the optimum cycle of an inverter heat pump as a function of frequency. The performance of an inverter heat pump was measured with a variation of frequency and length of capillary tube, and applying a newly designed bypass orifice. The inverter heat pump with the standard capillary tube that was optimum size at the rated frequency and ASHRAE test condition ``A'' was tested by varying frequency. The optimum cycles were also investigated by changing the length of capillary tube at individual level of low, rated, and high frequency. Since the inverter heat pump with a capillary tube does not provide optimal cycles at all operating frequencies, a bypass orifice was invented to improve the performance of the system at the wide frequency range. The flow rate change of the bypass orifice with respect to frequency was higher than that of the capillary tube. As a results of applying the bypass orifice to the inverter heat pump system, the performance was enhanced in the low frequency level compared with the conventional expansion device of a capillary tube.

5. Optimization of circular orifice jets mixing into a heated cross flow in a cylindrical duct

NASA Technical Reports Server (NTRS)

Kroll, J. T.; Sowa, W. A.; Samuelsen, G. S.; Holdeman, J. D.

1993-01-01

To examine the mixing characteristics of circular jets in an axisymmetric can geometry, temperature measurements were obtained downstream of a row of cold jet injected into a heated cross stream. The objective was to obtain uniform mixing within one duct radius downstream of the leading edge of the jet orifices. An area weighted standard deviation of the mixture fraction was used to help quantify the degree of mixedness at a given plane. Non-reacting experiments were conducted to determine the influence of the number of jets on the mixedness in a cylindrical configuration. Results show that the number of orifices significantly impacts the mixing characteristics of jets injected from round hole orifices in a can geometry. Optimum mixing occurs when the mean jet trajectory aligns with the radius which divides the cross sectional area of the can into two equal parts at one mixer radius downstream of the leading edge of the orifice. The optimum number of holes at momentum-flux ratios of 25 and 52 is 10 and 15 respectively.

6. Bubble Formation from Wall Orifice in Liquid Cross-Flow Under Low Gravity

NASA Technical Reports Server (NTRS)

Nahra, Henry K.; Kamotani, Y.

2000-01-01

Two-phase flows present a wide variety of applications for spacecraft thermal control systems design. Bubble formation and detachment is an integral part of the two phase flow science. The objective of the present work is to experimentally investigate the effects of liquid cross-flow velocity, gas flow rate, and orifice diameter on bubble formation in a wall-bubble injection configuration. Data were taken mainly under reduced gravity conditions but some data were taken in normal gravity for comparison. The reduced gravity experiment was conducted aboard the NASA DC-9 Reduced Gravity Aircraft. The results show that the process of bubble formation and detachment depends on gravity, the orifice diameter, the gas flow rate, and the liquid cross-flow velocity. The data are analyzed based on a force balance, and two different detachment mechanisms are identified. When the gas momentum is large, the bubble detaches from the injection orifice as the gas momentum overcomes the attaching effects of liquid drag and inertia. The surface tension force is much reduced because a large part of the bubble pinning edge at the orifice is lost as the bubble axis is tilted by the liquid flow. When the gas momentum is small, the force balance in the liquid flow direction is important, and the bubble detaches when the bubble axis inclination exceeds a certain angle.

7. Class 1 neural excitability, conventional synapses, weakly connected networks, and mathematical foundations of pulse-coupled models.

PubMed

Izhikevich, E M

1999-01-01

Many scientists believe that all pulse-coupled neural networks are toy models that are far away from the biological reality. We show here, however, that a huge class of biophysically detailed and biologically plausible neural-network models can be transformed into a canonical pulse-coupled form by a piece-wise continuous, possibly noninvertible, change of variables. Such transformations exist when a network satisfies a number of conditions; e.g., it is weakly connected; the neurons are Class 1 excitable (i.e., they can generate action potentials with an arbitrary small frequency); and the synapses between neurons are conventional (i.e., axo-dendritic and axo-somatic). Thus, the difference between studying the pulse-coupled model and Hodgkin-Huxley-type neural networks is just a matter of a coordinate change. Therefore, any piece of information about the pulse-coupled model is valuable since it tells something about all weakly connected networks of Class 1 neurons. For example, we show that the pulse-coupled network of identical neurons does not synchronize in-phase. This confirms Ermentrout's result that weakly connected Class 1 neurons are difficult to synchronize, regardless of the equations that describe dynamics of each cell.

8. A multiscale, hierarchical model of pulse dynamics in arid-land ecosystems

USGS Publications Warehouse

Collins, Scott L.; Belnap, Jayne; Grimm, N. B.; Rudgers, J. A.; Dahm, Clifford N.; D'Odorico, P.; Litvak, M.; Natvig, D. O.; Peters, Douglas C.; Pockman, W. T.; Sinsabaugh, R. L.; Wolf, B. O.

2014-01-01

Ecological processes in arid lands are often described by the pulse-reserve paradigm, in which rain events drive biological activity until moisture is depleted, leaving a reserve. This paradigm is frequently applied to processes stimulated by one or a few precipitation events within a growing season. Here we expand the original framework in time and space and include other pulses that interact with rainfall. This new hierarchical pulse-dynamics framework integrates space and time through pulse-driven exchanges, interactions, transitions, and transfers that occur across individual to multiple pulses extending from micro to watershed scales. Climate change will likely alter the size, frequency, and intensity of precipitation pulses in the future, and arid-land ecosystems are known to be highly sensitive to climate variability. Thus, a more comprehensive understanding of arid-land pulse dynamics is needed to determine how these ecosystems will respond to, and be shaped by, increased climate variability.

9. A study of the discharge coefficient of jets from angled slots and conical orifices

Linfield, Kevin William

2000-10-01

Non-ideal flows through angled orifices occur often in engineering applications such as mass flow meters, blast-wave simulators, gas propulsion devices and projectile launchers. For such flows, a correction factor in the form of a discharge coefficient is required to facilitate good design and efficient operation. The discharge coefficient depends on many parameters including atmospheric to stagnation pressure ratio, gas specific heat ratio, exit to channel area ratio, orifice shape, wall angle and orifice edge rounding. The dependence on these parameters (except edge rounding) was studied numerically by developing a two-dimensional finite-difference computer program that solves the subsonic flowfield in the hodograph plane by a relaxation method and the attached supersonic flowfield, if present, in the physical plane by a method of characteristics, joined together at the sonic surface by matching stream function values. The discharge coefficient was also studied experimentally by developing and testing an experimental facility using a new technique based on the partial blowdown of a pressurized vessel through a short pipe ending with conical orifices of different area ratios, wall angles and orifice edge roundings. Numerical and experimental data from these studies and also from the literature are compared and discussed. A software package called the " Cd Algorithm" was developed to reproduce quickly the combined numerical and experimental discharge coefficients for the entire set of parameters, and it outperforms previous algorithms in accuracy, efficiency and comprehensiveness. This Cd Algorithm uses analytical, numerical and experimental results at the limits for incompressible, critical and choked flows, and other Cd values between these limits are reproduced by using piecewise cubic polynomial splines.

10. On the propagation mechanism of a detonation wave in a round tube with orifice plates

Ciccarelli, G.; Cross, M.

2016-09-01

This study deals with the investigation of the detonation propagation mechanism in a circular tube with orifice plates. Experiments were performed with hydrogen air in a 10-cm-inner-diameter tube with the second half of the tube filled with equally spaced orifice plates. A self-sustained Chapman-Jouguet (CJ) detonation wave was initiated in the smooth first half of the tube and transmitted into the orifice-plate-laden second half of the tube. The details of the propagation were obtained using the soot-foil technique. Two types of foils were used between obstacles, a wall-foil placed on the tube wall, and a flat-foil (sooted on both sides) placed horizontally across the diameter of the tube. When placed after the first orifice plate, the flat foil shows symmetric detonation wave diffraction and failure, while the wall foil shows re-initiation via multiple local hot spots created when the decoupled shock wave interacts with the tube wall. At the end of the tube, where the detonation propagated at an average velocity much lower than the theoretical CJ value, the detonation propagation is much more asymmetric with only a few hot spots on the tube wall leading to local detonation initiation. Consecutive foils also show that the detonation structure changes after each obstacle interaction. For a mixture near the detonation propagation limit, detonation re-initiation occurs at a single wall hot spot producing a patch of small detonation cells. The local overdriven detonation wave is short lived, but is sufficient to keep the global explosion front propagating. Results associated with the effect of orifice plate blockage and spacing on the detonation propagation mechanism are also presented.

11. Modelling inactivation of Listeria monocytogenes by pulsed electric fields in media of different pH.

PubMed

Gómez, N; García, D; Alvarez, I; Condón, S; Raso, J

2005-08-25

A study of the effect of square-wave pulsed electric fields (PEF) on the inactivation of Listeria monocytogenes in McIlvaine buffer of different pH (3.5-7.0) was conducted. L. monocytoges was more PEF sensitive at higher electric field strengths (E) and in media of low pH. A treatment at 28 kV/cm for 400 mus that inactivated 1.5, 2.3 and 3.0 Log10 cycles at pH 7.0, 6.5 and 5.0 respectively destroyed almost 6.0 Log10 cycles at pH 3.5. The general shape of survival curves of L. monocytogenes PEF treated at different pH was convex/concave upwards. A mathematical model based on the Weibull distribution accurately described these survival curves. At each pH, the shape parameter (n value) did not depend on E. The relationship between n value of the Weibull model and the pH of the treatment medium was described by the Gompertz equation. A multiple linear regression model using three predictor variables (E, E2, pH2) related the Log10 of the scale paramenter (b value) of the Weibull model with E and pH of the treatment medium. A tertiary model developed using McIlvaine buffer as treatment medium predicted satisfactorily the inactivation of L. monocytogenes in apple juice.

12. A kinetic model for estimating net photosynthetic rates of cos lettuce leaves under pulsed light.

PubMed

Jishi, Tomohiro; Matsuda, Ryo; Fujiwara, Kazuhiro

2015-04-01

Time-averaged net photosynthetic rate (P n) under pulsed light (PL) is known to be affected by the PL frequency and duty ratio, even though the time-averaged photosynthetic photon flux density (PPFD) is unchanged. This phenomenon can be explained by considering that photosynthetic intermediates (PIs) are pooled during light periods and then consumed by partial photosynthetic reactions during dark periods. In this study, we developed a kinetic model to estimate P n of cos lettuce (Lactuca sativa L. var. longifolia) leaves under PL based on the dynamics of the amount of pooled PIs. The model inputs are average PPFD, duty ratio, and frequency; the output is P n. The rates of both PI accumulation and consumption at a given moment are assumed to be dependent on the amount of pooled PIs at that point. Required model parameters and three explanatory variables (average PPFD, frequency, and duty ratio) were determined for the simulation using P n values under PL based on several combinations of the three variables. The model simulation for various PL levels with a wide range of time-averaged PPFDs, frequencies, and duty ratios further demonstrated that P n under PL with high frequencies and duty ratios was comparable to, but did not exceed, P n under continuous light, and also showed that P n under PL decreased as either frequency or duty ratio was decreased. The developed model can be used to estimate P n under various light environments where PPFD changes cyclically.

13. Simple Two-Dimensional Corrections for One-Dimensional Pulse Tube Models

NASA Technical Reports Server (NTRS)

Lee, J. M.; Kittel, P.; Timmerhaus, K. D.; Radebaugh, R.

2004-01-01

One-dimensional oscillating flow models are very useful for designing pulse tubes. They are simple to use, not computationally intensive, and the physical relationship between temperature, pressure and mass flow are easy to understand when used in conjunction with phasor diagrams. They do not possess, however, the ability to directly calculate thermal and momentum diffusion in the direction transverse to the oscillating flow. To account for transverse effects, lumped parameter corrections, which are obtained though experiment, must be used. Or two-dimensional solutions of the differential fluid equations must be obtained. A linear two-dimensional solution to the fluid equations has been obtained. The solution provides lumped parameter corrections for one-dimensional models. The model accounts for heat transfer and shear flow between the gas and the tube. The complex Nusselt number and complex shear wall are useful in describing these corrections, with phase relations and amplitudes scaled with the Prandtl and Valensi numbers. The calculated ratio, a, between a two-dimensional solution of the oscillating temperature and velocity and a one-dimensional solution for the same shows a scales linearly with Va for Va less than 30. In this region alpha less than 0.5, that is, the enthalpy flow calculated with a two-dimensional model is 50% of a calculation using a one-dimensional model. For Va greater than 250, alpha = 0.8, showing that diffusion is still important even when it is confined to a thing layer near the tube wall.

14. Modeling of gas ionization and plasma flow in ablative pulsed plasma thrusters

Huang, Tiankun; Wu, Zhiwen; Liu, Xiangyang; Xie, Kan; Wang, Ningfei; Cheng, Yue

2016-12-01

A one-dimensional model to study the gas ionization and plasma flow in ablative pulsed plasma thrusters(APPTs) is established in this paper. The discharge process of the APPT used in the LES-6 satellite is simulated to validate the model. The simulation results for the impulse bit and propellant utilization give values of 29.05 μN s and 9.56%, respectively, which are in good agreement with experimental results. To test the new ionization sub-model, the discharge process of a particular APPT, XPPT-1, is simulated, and a numerical result for the propellant utilization of 62.8% is obtained, which also agrees well with experiment. The gas ionization simulation results indicate that an APPT with a lower average propellant ablation rate and higher average electric field intensity between electrodes should have higher propellant utilization. The plasma density distribution between the electrodes of APPTs can also be obtained using the new model, and the numerical results show that the plasma generation and flow are discontinuous, which is in good agreement with past experimental results of high-speed photography. This model provides a new tool with which to study the physical mechanisms of APPTs and a reference for the design of high-performance APPTs.

15. Diagnostic accuracy of a mathematical model to predict apnea-hypopnea index using nighttime pulse oximetry

Ebben, Matthew R.; Krieger, Ana C.

2016-03-01

The intent of this study is to develop a predictive model to convert an oxygen desaturation index (ODI) to an apnea-hypopnea index (AHI). This model will then be compared to actual AHI to determine its precision. One thousand four hundred and sixty-seven subjects given polysomnograms with concurrent pulse oximetry between April 14, 2010, and February 7, 2012, were divided into model development (n=733) and verification groups (n=734) in order to develop a predictive model of AHI using ODI. Quadratic regression was used for model development. The coefficient of determination (r2) between the actual AHI and the predicted AHI (PredAHI) was 0.80 (r=0.90), which was significant at a p<0.001. The areas under the receiver operating characteristic curve ranged from 0.96 for AHI thresholds of ≥10 and ≥15/h to 0.97 for thresholds of ≥5 and ≥30/h. The algorithm described in this paper provides a convenient and accurate way to convert ODI to a predicted AHI. This tool makes it easier for clinicians to understand oximetry data in the context of traditional measures of sleep apnea.

16. Exploration of the retroperitoneum using the transvaginal natural orifice transluminal endoscopic surgery technique.

PubMed

Zacharopoulou, Chrysoula; Nassif, Joseph; Allemann, Pierre; Dallemagne, Bernard; Perretta, Silvana; Marescaux, Jacques; Wattiez, Arnaud

2009-01-01

We sought to evaluate the feasibility of the retroperitoneum's exploration via natural orifice transluminal endoscopic surgery (NOTES) using transvaginal access in a porcine model, and its possible application in human beings. Six female pigs (25-30 kg) were used to establish anatomic landmarks and technical steps. Six additional pigs were used for the survival study. Under general anesthesia and with the pig supine, a 1-cm posterolateral colpotomy was performed with the double-channel gastroscope's needle knife. The incision was enlarged laterally using blunt dissection while keeping in contact with the psoas muscle. A retroperitoneal tunnel was created using carbon-dioxide dissection and the movements of the gastroscope up to the level of the kidney. The colpotomy site was closed using interrupted sutures (polyglactin 2/0). A follow-up laparoscopy and necropsy were performed 3 weeks postoperatively. Successful access to the retroperitoneum was achieved in all pigs with a mean operative time of 30 minutes. However, in the first 3 pigs used for the acute study, the peritoneum was perforated during the six-pig dissection and the procedure was abandoned because of the space's collapse. No perforation occurred during the survival study. An excellent view of the retroperitoneal space and structures, such as the vascular and lymphatic tissues, the kidney, the adrenal gland, and the ureter, was obtained. No intraoperative complications or bleeding or injury to any of the retroperitoneal structures occurred. The 3-week follow-up laparoscopy showed no adhesions or abscesses. These findings were confirmed at necropsy. The retroperitoneal space can be successfully accessed via NOTES. Transvaginal NOTES access to the retroperitoneum avoids any transparietal trocars, so it could decrease surgical trauma, be better tolerated, and offer better visualization, with the obvious gender limitation. Future clinical application in human beings may include procedures such as

17. Implications of rapid rotation for pulse profile models of millisecond-period x-ray pulsars

2007-08-01

The rapid rotation of recycled neutron stars in accretion-powered millisecond- period X-ray pulsars has important consequences for models of their pulsed emission, and by extension, the analysis of observations of these objects. We begin by considering the problem of calculating the time-varying bolometric flux arising due to emission from a bright spot on the surface of a rapidly rotating neutron star, with rotational period on the order of a millisecond. We restrict to the case of isotropic emission from an infinitesimal emission zone, but carry out the calculations with sufficient generality to incorporate a precisely solved spacetime metric and stellar structure. The geodesic equation is integrated numerically. Using the computer code developed for this work, we investigate the effect that commonly-used simplifying approximations have on the shape of the pulse profile compared to the full calculation. In particular, we consider the effect of neglecting the phase-dependent travel time of photons, approximating the exterior metric as either Schwarzschild or Kerr, and neglecting the rotation- induced oblateness of the neutron star. We also consider the consequences that result when approximate pulse profiles are used to obtain neutron star parameters such as mass, radius, emission inclination, and observer inclination via least squares fitting. Specifically, we look at fitting light curves calculated using the Schwarzschild metric and a spherical star to a light curve calculated using a precisely-solved metric and stellar structure. We are able to conclude that, in an idealised case where there is no random noise component and all light curves are for bolometric fluxes from isotropic emission, neglecting photon times-of-flight or stellar oblateness in model light curves used for fitting can introduce errors at the level of several tens of percent on the determination of mass and radius individually. However, these errors will often offset each other such that the

18. Modeling of pulsed heat load in a cryogenic SHe loop using Artificial Neural Networks

Savoldi Richard, L.; Bonifetto, R.; Carli, S.; Grand Blanc, M.; Zanino, R.

2013-10-01

The pulsed heat load to the cryoplant is an important issue in the design and operation of tokamaks adopting superconducting (SC) magnets for the magnetic confinement, as the International Thermonuclear Experimental Reactor (ITER). The smoothing of the heat load during plasma operation is being addressed by experiments, e.g. in the HELIOS facility at CEA Grenoble, and simulations. The assessment of the operation of the cryoplant mainly requires the knowledge of the evolution of the heat load to the liquid helium (LHe) baths that are used as interfaces/buffers between the magnets cooling loops and the cryoplant itself. In this paper, an innovative approach based on Artificial Neural Networks (ANNs) is presented, leading to a simplified but fast model of the transient heat load from the magnets to the LHe baths. An ANN model is developed for the HELIOS loop and the resulting network is trained using detailed transient simulations performed with the 4C code, which was previously extensively validated against experimental data from HELIOS. The predictive capability of the (simplified) ANN model is then demonstrated by considering another, independent dataset, not used during the ANN training, and comparing the evolution of the heat load to the LHe bath computed by the ANNs with that obtained from the (detailed) 4C model.

19. An innovative numerical approach to resolve the pulse wave velocity in a healthy thoracic aorta model.

PubMed

Yang, An-Shik; Wen, Chih-Yung; Tseng, Li-Yu; Chiang, Chih-Chieh; Tseng, Wen-Yih Isaac; Yu, Hsi-Yu

2014-04-01

Aortic dissection and atherosclerosis are highly fatal diseases. The development of both diseases is closely associated with highly complex haemodynamics. Thus, in predicting the onset of cardiac disease, it is desirable to obtain a detailed understanding of the flowfield characteristics in the human cardiovascular circulatory system. Accordingly, in this study, a numerical model of a normal human thoracic aorta is constructed using the geometry information obtained from a phase-contrast magnetic resonance imaging (PC-MRI) technique. The interaction between the blood flow and the vessel wall dynamics is then investigated using a coupled fluid-structure interaction (FSI) analysis. The simulations focus specifically on the flowfield characteristics and pulse wave velocity (PWV) of the blood flow. Instead of using a conventional PC-MRI method to measure PWV, we present an innovative application of using the FSI approach to numerically resolve PWV for the assessment of wall compliance in a thoracic aorta model. The estimated PWV for a normal thoracic aorta agrees well with the results obtained via PC-MRI measurement. In addition, simulations which consider the FSI effect yield a lower predicted value of the wall shear stress at certain locations in the cardiac cycle than models which assume a rigid vessel wall. Consequently, the model provides a suitable basis for the future development of more sophisticated methods capable of performing the computer-aided analysis of aortic blood flows.

20. Analysis of pulsed eddy current data using regression models for steam generator tube support structure inspection

Buck, J. A.; Underhill, P. R.; Morelli, J.; Krause, T. W.

2016-02-01

Nuclear steam generators (SGs) are a critical component for ensuring safe and efficient operation of a reactor. Life management strategies are implemented in which SG tubes are regularly inspected by conventional eddy current testing (ECT) and ultrasonic testing (UT) technologies to size flaws, and safe operating life of SGs is predicted based on growth models. ECT, the more commonly used technique, due to the rapidity with which full SG tube wall inspection can be performed, is challenged when inspecting ferromagnetic support structure materials in the presence of magnetite sludge and multiple overlapping degradation modes. In this work, an emerging inspection method, pulsed eddy current (PEC), is being investigated to address some of these particular inspection conditions. Time-domain signals were collected by an 8 coil array PEC probe in which ferromagnetic drilled support hole diameter, depth of rectangular tube frets and 2D tube off-centering were varied. Data sets were analyzed with a modified principal components analysis (MPCA) to extract dominant signal features. Multiple linear regression models were applied to MPCA scores to size hole diameter as well as size rectangular outer diameter tube frets. Models were improved through exploratory factor analysis, which was applied to MPCA scores to refine selection for regression models inputs by removing nonessential information.

1. Model and computer simulations of the motion of DNA molecules during pulse field gel electrophoresis

SciTech Connect

Smith, S.B.; Bustamante, C. ); Heller, C. )

1991-05-28

A model is presented for the motion of individual molecules of DNA undergoing pulse field gel electrophoresis (PFGE). The molecule is represented by a chain of charged beads connected by entropic springs, and the gel is represented by a segmented tube surrounding the beads. This model differs from earlier reptation/tube models in that the tube is allowed to leak in certain places and the chain can double over and flow out of the side of the tube in kinks. It is found that these kinks often lead to the formation of U shapes, which are a major source of retardation in PFGE. The results of computer simulations using this model are compared with real DNA experimental results for the following cases: steady field motion as seen in fluorescence microscopy, mobility in steady fields, mobility in transverse field alternation gel electrophoresis (TFAGE), mobility in field inversion gel electrophoresis (FIGE), and linear dichroism (LD) of DNA in agarose gels during PFGE. Good agreement between the simulations and the experimental results is obtained.

2. Biokinetic food chain modeling of waterborne selenium pulses into aquatic food chains: Implications for water quality criteria.

PubMed

DeForest, David K; Pargee, Suzanne; Claytor, Carrie; Canton, Steven P; Brix, Kevin V

2016-04-01

We evaluated the use of biokinetic models to predict selenium (Se) bioaccumulation into model food chains after short-term pulses of selenate or selenite into water. Both periphyton- and phytoplankton-based food chains were modeled, with Se trophically transferred to invertebrates and then to fish. Whole-body fish Se concentrations were predicted based on 1) the background waterborne Se concentration, 2) the magnitude of the Se pulse, and 3) the duration of the Se pulse. The models were used to evaluate whether the US Environmental Protection Agency's (USEPA's) existing acute Se criteria and their recently proposed intermittent Se criteria would be protective of a whole-body fish Se tissue-based criterion of 8.1 μg g(-1) dry wt. Based on a background waterborne Se concentration of 1 μg L(-1) and pulse durations of 1 d and 4 d, the Se pulse concentrations predicted to result in a whole-body fish Se concentration of 8.1 μg g(-1) dry wt in the most conservative model food chains were 144 and 35 μg L(-1), respectively, for selenate and 57 and 16 μg L(-1), respectively, for selenite. These concentrations fall within the range of various acute Se criteria recommended by the USEPA based on direct waterborne toxicity, suggesting that these criteria may not always be protective against bioaccumulation-based toxicity that could occur after short-term pulses. Regarding the USEPA's draft intermittent Se criteria, the biokinetic modeling indicates that they may be overly protective for selenate pulses but potentially underprotective for selenite pulses. Predictions of whole-body fish Se concentrations were highly dependent on whether the food chain was periphyton- or phytoplankton-based, because the latter had much greater Se uptake rate constants. Overall, biokinetic modeling provides an approach for developing acute Se criteria that are protective against bioaccumulation-based toxicity after trophic transfer, and it is also a useful tool for evaluating averaging

3. Pulse!!: a model for research and development of virtual-reality learning in military medical education and training.

PubMed

Dunne, James R; McDonald, Claudia L

2010-07-01

Pulse!! The Virtual Clinical Learning Lab at Texas A&M University-Corpus Christi, in collaboration with the United States Navy, has developed a model for research and technological development that they believe is an essential element in the future of military and civilian medical education. The Pulse!! project models a strategy for providing cross-disciplinary expertise and resources to educational, governmental, and business entities challenged with meeting looming health care crises. It includes a three-dimensional virtual learning platform that provides unlimited, repeatable, immersive clinical experiences without risk to patients, and is available anywhere there is a computer. Pulse!! utilizes expertise in the fields of medicine, medical education, computer science, software engineering, physics, computer animation, art, and architecture. Lab scientists collaborate with the commercial virtual-reality simulation industry to produce research-based learning platforms based on cutting-edge computer technology.

SciTech Connect

Swift, R P

1984-08-01

Realizing the full potential of gas-bearing deposits, such as the Eastern Devonian gas shales, requires an increased understanding of Tailored-Pulse Loading (TPL) stimulation techniques to initiate and extend multiple fractures. This is demonstrated in discussions of TPL phenomenology and of the limitations of past and current models to fully account for the mutual dependence of the governing processes and constraints. The processes include non-linear material deformation, porous flow, fracture, and fluid flow in fractures; the constraints consist of in-situ stresses, saturation, natural fractures and joints, and the TPL-source characteristics. Comprehensive modeling is one which unifies models governing each process with conditions defining the constraints, and accounts for their interaction in a coupled manner. An approach is proposed to model TPL in a unified manner that is hybrid in nature: it involves the use of state-of-the-art models combining both numerical and analytical solutions; the numerical solutions will be based both on finite-element and finite-difference algorithms. Efforts are defined to focus on the fracture initiation phase in parallel with the fracture extension phase for multiple fracturing. Various micro and macro fracture models with the coupling of porous flow effects will be under consideration for the initiation phase. Analyses of multiple fracture extension phase will include the treatment of fractures as being discrete, the influence of natural discontinuities such as joints and existing fractures, and the viscous behavior of fluid flow within fractures and joints. In addition, the linking of models for the initiation and extension phases within the framework of a single code will be pursued. 97 references, 3 figures.

5. Analytical modeling of transport aircraft crash scenarios to obtain floor pulses

NASA Technical Reports Server (NTRS)

Wittlin, G.; Lackey, D.

1983-01-01

The KRAS program was used to analyze transport aircraft candidate crash scenarios. Aircraft floor pulses and seat/occupant responses are presented. Results show that: (1) longitudinal only pulses can be represented by equivalent step inputs and/or static requirements; (2) the L1649 crash test floor longitudinal pulse for the aft direction (forward inertia) is less than 9g static or an equivalent 5g pulse; aft inertia accelerations are extremely small ((ch76) 3g) for representative crash scenarios; (3) a viable procedure to relate crash scenario floor pulses to standard laboratory dynamic and static test data using state of the art analysis and test procedures was demonstrated; and (4) floor pulse magnitudes are expected to be lower for wide body aircraft than for smaller narrow body aircraft.

6. Porcine skin visible lesion thresholds for near-infrared lasers including modeling at two pulse durations and spot sizes

Cain, Clarence P.; Polhamus, Garrett D.; Roach, William P.; Stolarski, David J.; Schuster, Kurt J.; Stockton, Kevin; Rockwell, Benjamin A.; Chen, Bo; Welch, Ashley J.

2006-07-01

With the advent of such systems as the airborne laser and advanced tactical laser, high-energy lasers that use 1315-nm wavelengths in the near-infrared band will soon present a new laser safety challenge to armed forces and civilian populations. Experiments in nonhuman primates using this wavelength have demonstrated a range of ocular injuries, including corneal, lenticular, and retinal lesions as a function of pulse duration. American National Standards Institute (ANSI) laser safety standards have traditionally been based on experimental data, and there is scant data for this wavelength. We are reporting minimum visible lesion (MVL) threshold measurements using a porcine skin model for two different pulse durations and spot sizes for this wavelength. We also compare our measurements to results from our model based on the heat transfer equation and rate process equation, together with actual temperature measurements on the skin surface using a high-speed infrared camera. Our MVL-ED50 thresholds for long pulses (350 µs) at 24-h postexposure are measured to be 99 and 83 Jcm-2 for spot sizes of 0.7 and 1.3 mm diam, respectively. Q-switched laser pulses of 50 ns have a lower threshold of 11 Jcm-2 for a 5-mm-diam top-hat laser pulse.

7. Modeling of cluster organization in metal-doped oxide glasses irradiated by a train of femtosecond laser pulses

Smetanina, Evgeniya; Chimier, Benoit; Petit, Yannick; Varkentina, Nadezda; Fargin, Evelyne; Hirsch, Lionel; Cardinal, Thierry; Canioni, Lionel; Duchateau, Guillaume

2016-01-01

The formation of silver cluster structures at submicrometer spatial scales under the irradiation by high-power femtosecond laser pulses with high repetition rate was observed in various glasses containing silver ions. In order to account for the formation of these structures in metal-doped glasses, we present a theoretical model for the organization of noble metallic clusters induced by a train of femtosecond laser pulses. The model includes photoionization and laser heating of the sample, diffusion, kinetic reactions, and dissociation of metallic species. This model was applied to reproduce the formation of cluster structures in silver-doped phosphate glass. The parameters of the silver structures were obtained numerically under various incident pulse intensities and number of pulses. Numerical modeling shows that the involved microscopic physical and chemical processes naturally lead to the emergence of a silver cluster organization, together with charge migration and subsequent trapping giving rise to a strong static electric field buried in the irradiated area as experimentally observed. Based on this modeling, a theoretical basis is provided for the design of new metallic cluster structures with nanoscale size.

8. Modeling and Numerical Simulation of Microwave Pulse Propagation in Air Breakdown Environment

NASA Technical Reports Server (NTRS)

Kuo, S. P.; Kim, J.

1991-01-01

Numerical simulation is used to investigate the extent of the electron density at a distant altitude location which can be generated by a high-power ground-transmitted microwave pulse. This is done by varying the power, width, shape, and carrier frequency of the pulse. The results show that once the breakdown threshold field is exceeded in the region below the desired altitude location, electron density starts to build up in that region through cascading breakdown. The generated plasma attenuates the pulse energy (tail erosion) and thus deteriorates the energy transmission to the destined altitude. The electron density saturates at a level limited by the pulse width and the tail erosion process. As the pulse continues to travel upward, though the breakdown threshold field of the background air decreases, the pulse energy (width) is reduced more severely by the tail erosion process. Thus, the electron density grows more quickly at the higher altitude, but saturates at a lower level. Consequently, the maximum electron density produced by a single pulse at 50 km altitude, for instance, is limited to a value below 10(exp 6) cm(exp -3). Three different approaches are examined to determine if the ionization at the destined location can be improved: a repetitive pulse approach, a focused pulse approach, and two intersecting beams. Only the intersecting beam approach is found to be practical for generating the desired density level.

9. Time-Domain Modeling of Electromagnetic Pulses Returned from Targets in Dispersive and Dissipative Media

Gaunaurd, G. C.; Strifors, H. C.; Sullivan, A.

2008-06-01

Using a Method-of-Moments (MoM) code, we earlier simulated ultra-wideband (UWB) returned echoes from two targets, one penetrable and one impenetrable, buried in a soil with known electric properties. The simple shape of mines, coupled with their predictable deployment in the ground, has also provided a fundamental understanding of the underlying backscatter phenomenology. In particular, the backscattered waveform from a mine can be decomposed into a collection of closely spaced copies of an elemental wave object with different amplitudes and time delays. This wave object is here defined as the derivative of the waveform incident on the target. The spacing of the copies or replicas of the wave object could be determined by the round trip time delay between scattering centers. This methodology was previously applied to impenetrable targets and is now applied also to a penetrable target. The previously computed returns from each target for a given incident pulse are modeled by a few copies of the elemental wave object with the time delay and amplitude of each copy taken as unknown parameters. These parameters are then determined by minimizing in the least square sense the difference between the MoM computed signal and the model signal using the differential evolution method (DEM). The methodology is extended by way of our previously developed target translated method (TTM) to approximate the computation of the backscattered model signal when the target is buried at a different depth in the soil with a different moisture content.

10. Real-time robot path planning based on a modified pulse-coupled neural network model.

PubMed

Qu, Hong; Yang, Simon X; Willms, Allan R; Yi, Zhang

2009-11-01

This paper presents a modified pulse-coupled neural network (MPCNN) model for real-time collision-free path planning of mobile robots in nonstationary environments. The proposed neural network for robots is topologically organized with only local lateral connections among neurons. It works in dynamic environments and requires no prior knowledge of target or barrier movements. The target neuron fires first, and then the firing event spreads out, through the lateral connections among the neurons, like the propagation of a wave. Obstacles have no connections to their neighbors. Each neuron records its parent, that is, the neighbor that caused it to fire. The real-time optimal path is then the sequence of parents from the robot to the target. In a static case where the barriers and targets are stationary, this paper proves that the generated wave in the network spreads outward with travel times proportional to the linking strength among neurons. Thus, the generated path is always the global shortest path from the robot to the target. In addition, each neuron in the proposed model can propagate a firing event to its neighboring neuron without any comparing computations. The proposed model is applied to generate collision-free paths for a mobile robot to solve a maze-type problem, to circumvent concave U-shaped obstacles, and to track a moving target in an environment with varying obstacles. The effectiveness and efficiency of the proposed approach is demonstrated through simulation and comparison studies.

11. Design considerations for pulsed-flow comprehensive two-dimensional GC: dynamic flow model approach.

PubMed

2010-04-01

A dynamic flow model, which maps carrier gas pressures and carrier gas flow rates through the first dimension separation column, the modulator sample loop, and the second dimension separation column(s) in a pulsed-flow modulation comprehensive two-dimensional gas chromatography (PFM-GCxGC) system is described. The dynamic flow model assists design of a PFM-GCxGC modulator and leads to rapid determination of pneumatic conditions, timing parameters, and the dimensions of the separation columns and connecting tubing used to construct the PFM-GCxGC system. Three significant innovations are introduced in this manuscript, which were all uncovered by using the dynamic flow model. A symmetric flow path modulator improves baseline stability, appropriate selection of the flow restrictors in the first dimension column assembly provides a generally more stable and robust system, and these restrictors increase the modulation period flexibility of the PFM-GCxGC system. The flexibility of a PFM-GCxGC system resulting from these innovations is illustrated using the same modulation interface to analyze Special Antarctic Blend (SAB) diesel using 3 s and 9 s modulation periods.

12. Finite element analysis modeling of pulse-laser excited photothermal deflection (mirage effect) from aerosols.

PubMed

Dada, Oluwatosin O; Bialkowski, Stephen E

2008-12-01

A finite element analysis method for numerical modeling of the photothermal deflection spectroscopy of aerosols is presented. The models simulate pulse-laser excited photothermal deflection from aerosols collected on a plane surface substrate in air medium. The influence of the aerosol and substrate properties on the transient photothermal deflection signal is examined. We have previously obtained experimental results for photothermal deflection spectrometry of aerosols deposited onto a plate from an impactor system (O. O. Dada and S. E. Bialkowski, Appl. Spectrosc. 62, 1336 (2008)). This paper supports the validity of the experimental results presented in that paper and helps in answering some of the questions raised. The modeling results presented here demonstrate that the (peak) normalized transient temperature change profile and (peak) normalized transient photothermal deflection profile are a good approximation and invariant with number of particles, inter-particle distance, and particulate shape, which suggests that the photothermal deflection signal amplitude may be calibrated linearly with total mass of aerosols and the method could be applied to analysis of complex aerosols.

13. Simplified modeling of pulsed corona for dielectric design of high-voltage devices

Pancheshnyi, Sergey; Schefer, Thomas

2016-09-01

Physics-based modeling of discharges in insulating gases (air, SF6, CO2 , etc.) is required for quantitative prediction of withstand voltages of high-voltage devices. Breakdown of not very long gaps at elevated pressures occurs typically by streamer (or spark) mechanism. Glow or streamer corona can delay the inception of breakdown streamers. This is often attributed to the so-called corona stabilization effect that is lowering of electric field close to the stressed electrodes due to corona space charge. However, compared to corona-less streamer breakdown of short gaps at elevated pressures, breakdown voltages are typically lower if corona starts. Direct simulation of discharges are often computationally costly, especially for 3D cases, and simplified engineering approaches are developing. Such models are then used for prediction of the ``worst-case scenario'', which might lead to breakdown of gaseous insulation in real design. The engineering models used for simulation of corona inception and development for different voltage shapes (DC, AC, pulsed) will be discussed for several geometries, including rod-plane case and electrode-less inception near a dielectric surface.

14. Parametric measurements of the effect of in-duct orifice edge shape on its noise damping performance

Ji, Chenzhen; Zhao, Dan; Han, Nuomin; Li, Jing

2016-12-01

Acoustic liners perforated with thousands of millimeter-size orifices are widely used in aero-engines and gas turbine engines as an effective noise damper. In this work, experimental investigations of the acoustic damping effect of in-duct perforated orifices are performed on a cold-flow pipe. A mean flow (also known as bias flow) is applied and its flow rate is variable. Emphasis is placed on the effect of the orifice edge shape. For this, 16 in-duct orifices with different edge shapes and porosities are designed and manufactured by using 3D printing technology and conventional laser cutting technique. The damping effect of these in-duct orifices is characterized by using power absorption coefficient Δ and reflection coefficient χ from 100 to 1000 Hz. The performances of these orifices are found to be either improved or deteriorated, depending on (1) edge shape, (2) the ratio T/d of orifice thickness to its diameter, (3) the bias flow Mach number, (4) downstream pipe length Ld and (5) porosity η via varying either the number N or surface area Ao of the orifices. In addition, modifying orifice edge does not lead to an increase of power absorption at lower frequency (⩽ 700 Hz). However, as the frequency is increased, the orifice with square (S-type) edge is found to be associated with 10 percent more power absorption. It is interesting to find that T/d over the tested range (≤ 0.5) has little influence on its damping capacity. However, the mean bias flow Mach number Ma and porosity η are shown to play critical roles on determining the noise damping performance of these orifices. Maximum power absorption Δmax is found to occur at Ma ≈ 0.018, while the optimum porosity corresponding to Δmax is approximately 7 percent. The present parametric measurements shed light on the roles of orifice edge shape, porosity and mean flow on its noise damping capacity, and facilitate the design of effective perforated liners.

15. Pulsed lasers versus continuous light sources in capillary electrophoresis and fluorescence detection studies: Photodegradation pathways and models.

PubMed

Boutonnet, Audrey; Morin, Arnaud; Petit, Pierre; Vicendo, Patricia; Poinsot, Véréna; Couderc, François

2016-03-17

Pulsed lasers are widely used in capillary electrophoresis (CE) studies to provide laser induced fluorescence (LIF) detection. Unfortunately pulsed lasers do not give linear calibration curves over a wide range of concentrations. While this does not prevent their use in CE/LIF studies, the non-linear behavior must be understood. Using 7-hydroxycoumarin (7-HC) (10-5000 nM), Tamra (10-5000 nM) and tryptophan (1-200 μM) as dyes, we observe that continuous lasers and LEDs result in linear calibration curves, while pulsed lasers give polynomial ones. The effect is seen with both visible light (530 nm) and with UV light (355 nm, 266 nm). In this work we point out the formation of byproducts induced by pulsed laser upon irradiation of 7-HC. Their separation by CE using two Zeta LIF detectors clearly shows that this process is related to the first laser detection. All of these photodegradation products can be identified by an ESI-/MS investigation and correspond to at least two 7HC dimers. By using the photodegradation model proposed by Heywood and Farnsworth (2010) and by taking into account the 7-HC results and the fact that in our system we do not have a constant concentration of fluorophore, it is possible to propose a new photochemical model of fluorescence in LIF detection. The model, like the experiment, shows that it is difficult to obtain linear quantitation curves with pulsed lasers while UV-LEDs used in continuous mode have this advantage. They are a good alternative to UV pulsed lasers. An application involving the separation and linear quantification of oligosaccharides labeled with 2-aminobezoic acid is presented using HILIC and LED (365 nm) induced fluorescence.

16. On the formation of vortex pairs near orifices

Blondeaux, P.; de Bernardinis, B.

1983-10-01

It is pointed out that a two-dimensional vortex pair is commonly generated by pushing fluid down a semiinfinite channel by means of an impulsively started piston. Sheffield (1977) calculated the trajecotories of an ideal vortex pair near channel openings of different shapes. The present investigation is concerned with a point-vortex model of the process of pair formation and a general extension of Sheffield's results. The assumption is made that viscous effects are significant only during the separation process and have negligible influence on the overall flow. In the limit of infinite Reynolds number, the problem becomes one of inviscid flow. The growing vortex sheets shed from the edge are represented by a simplified model reported by Brown and Michael (1954). The model is utilized to study the trajectories of two free vortices released symmetrically near the channel wall far from the opening of a semiinfinite channel when growing secondary vortices are present.

17. Analytic model and frequency characteristics of plasma synthetic jet actuator

Zong, Hao-hua; Wu, Yun; Li, Ying-hong; Song, Hui-min; Zhang, Zhi-bo; Jia, Min

2015-02-01

This paper reports a novel analytic model of a plasma synthetic jet actuator (PSJA), considering both the heat transfer effect and the inertia of the throat gas. Both the whole cycle characteristics and the repetitive working process of PSJA can be predicted with this model. The frequency characteristics of a PSJA with 87 mm3 volume and different orifice diameters are investigated based on the analytic model combined with experiments. In the repetitive working mode, the actuator works initially in the transitional stage with 20 cycles and then in the dynamic balanced stage. During the transitional stage, major performance parameters of PSJA experience stepped growth, while during the dynamic balanced stage, these parameters are characterized by periodic variation. With a constant discharge energy of 6.9 mJ, there exists a saturated frequency of 4 kHz/6 kHz for an orifice diameter of 1 mm/1.5 mm, at which the time-averaged total pressure of the pulsed jet reaches a maximum. Between 0.5 mm and 1.5 mm, a larger orifice diameter leads to a higher saturated frequency due to the reduced jet duration time. As the actuation frequency increases, both the time-averaged cavity temperature and the peak jet velocity initially increase and then remain almost unchanged at 1600 K and 280 m/s, respectively. Besides, with increasing frequency, the mechanical energy incorporated in single pulsed jet, the expelled mass per pulse, and the time-averaged density in the cavity, decline in a stair stepping way, which is caused by the intermittent decrease of refresh stage duration in one period.

18. Dynamic complexities in a pest control model with birth pulse and harvesting

Goel, A.; Gakkhar, S.

2016-04-01

In this paper, an impulsive model is discussed for an integrated pest management approach comprising of chemical and mechanical controls. The pesticides and harvesting are used to control the stage-structured pest population. The mature pest give birth to immature pest in pulses at regular intervals. The pest is controlled by spraying chemical pesticides affecting immature as well as mature pest. The harvesting of both immature and mature pest further reduce the pest population. The discrete dynamical system obtained from stroboscopic map is analyzed. The threshold conditions for stability of pest-free state as well as non-trivial period-1 solution is obtained. The effect of pesticide spray timing and harvesting on immature as well as mature pest are shown. Finally, by numerical simulation with MATLAB, the dynamical behaviors of the model is found to be complex. Above the threshold level there is a characteristic sequence of bifurcations leading to chaotic dynamics. Route to chaos is found to be period-doubling. Period halving bifurcations are also observed.

19. Time-dependent QED model for high-order harmonic generation in ultrashort intense laser pulses

Hu, Huayu; Yuan, Jianmin

2008-12-01

To advance the QED approach and exploit more details of the high-order harmonic generation (HHG) of atoms and molecules in intense ultrashort laser fields, a QED model for HHG is developed in a time-dependent framework and a multimode-laser setup. By introduction of the classical-field-dressed quantized Volkov states, an analytical expression to calculate HHG for hydrogenlike atoms and ions in an ultrashort intense laser pulse is obtained. This formula provides a simple intuitive interpretation of the mechanism in which the electron is first ionized to the classical-field-dressed quantized Volkov states, and then falls back to the ground state to emit the harmonic photon. Calculations using this formalism demonstrate a good agreement with recent semiclassical computations. The limiting of the existing QED models, which are successful in providing alternative perspectives on the HHG beyond semiclassical treatments, to the time-independent framework and the single-mode laser have been removed to take into account the laser pulse’s length and its shape. Possible extensive applications of this QED approach as well as its potential usefulness for research in various interesting fields are also discussed. The long-wavelength approximation and strong-field approximation are involved in the development of the formalism.

20. Highlighting the DNA damage response with ultrashort laser pulses in the near infrared and kinetic modeling

PubMed Central

Ferrando-May, Elisa; Tomas, Martin; Blumhardt, Philipp; Stöckl, Martin; Fuchs, Matthias; Leitenstorfer, Alfred

2013-01-01

Our understanding of the mechanisms governing the response to DNA damage in higher eucaryotes crucially depends on our ability to dissect the temporal and spatial organization of the cellular machinery responsible for maintaining genomic integrity. To achieve this goal, we need experimental tools to inflict DNA lesions with high spatial precision at pre-defined locations, and to visualize the ensuing reactions with adequate temporal resolution. Near-infrared femtosecond laser pulses focused through high-aperture objective lenses of advanced scanning microscopes offer the advantage of inducing DNA damage in a 3D-confined volume of subnuclear dimensions. This high spatial resolution results from the highly non-linear nature of the excitation process. Here we review recent progress based on the increasing availability of widely tunable and user-friendly technology of ultrafast lasers in the near infrared. We present a critical evaluation of this approach for DNA microdamage as compared to the currently prevalent use of UV or VIS laser irradiation, the latter in combination with photosensitizers. Current and future applications in the field of DNA repair and DNA-damage dependent chromatin dynamics are outlined. Finally, we discuss the requirement for proper simulation and quantitative modeling. We focus in particular on approaches to measure the effect of DNA damage on the mobility of nuclear proteins and consider the pros and cons of frequently used analysis models for FRAP and photoactivation and their applicability to non-linear photoperturbation experiments. PMID:23882280

1. Investigation of various equations of state for high current, pulsed power load modeling

Luginsland, John; Parkinson, Roland; Rigby, Fred; Toepfer, Alan

2002-08-01

A number of technologies utilize the increasing availability of modern pulsed power systems to produce high currents to resistively drive solid, metallic loads into the plasma state. Examples include ablation plasma deposition, circuit breakers, fuses, exploding and imploding wires, and high velocity jet disruption. One important feature in any computational model of these phenomena is the equation of state (EOS). The equations of state used in these models are typically as varied as the range of applications. In this work, using a segmented wire experiment performed at the Army Research Laboratory [1] as a benchmark, we investigate three equations of state [2-4]. We assess the merits of the EOS for both their physical accuracy and easy of use computationally. Finally, we comment on the availability of the information necessary to build the EOS, given the wide variety of materials that are used in this applied field. [1] C.E. Hollandsworth et al., J. Appl. Phys., vol. 84, no. 9, 4992-5000, 1998. [2] SESAME tables, LANL T-1 Division, Equation of State and Strength of Materials. [3] Zhukov, Demidov, and Ryabenko, Fiz. Metal. Metalloved., vol. 57, no. 2, 224-229, 1984. [4] Chittenden et al., Laser and Particle Beams, vol. 19, issue 3, 323-343, 2001, and references therein.

2. Acoustic gradient-index lens using orifice-type metamaterial unit cells

Park, Choon Mahn; Kim, Cho Hee; Park, Hee Tack; Lee, Sang Hun

2016-03-01

A gradient-index (GRIN) lens made of acoustic metamaterial is described that is assembled of unit cells with specific orifice characteristics. The GRIN distribution of the lens is established using different hole sizes for the unit cells. The intensity of the sound waves is demonstrated through simulations and confirmed by an experiment in a frequency band that satisfies the homogeneous medium constraints for the metamaterial. Experimental results from the focusing of sound waves of various frequencies agreed well with the expected values from the GRIN lens equation. This face-centered-orifice-cubic unit cell, which is nearly non-dispersive but asymmetric, appears to be a useful acoustic metamaterial for various acoustic devices operating with broadband frequencies.

3. Giant biatrial myxoma nearly obstructing the orifice of the inferior vena cava

PubMed Central

2013-01-01

Cardiac myxomas are the most common type of benign cardiac tumors and most of them occur in the left atrium but the biatrial myxoma is uncommon. We present a rare case of giant biatrial myxoma nearly obstructing the orifice of the inferior vena cava. A 58-year old woman presented with exertional dyspnea and intermittent chest discomfort. The non-pedunculated tumor involved most of the interatrial septum and extended from the orifice of the inferior vena cava to the displaced mitral annulus and the lower left pulmonary vein. The resected specimen weighed 76 gram and measured 80 × 40 × 30 mm. She did not complain of dyspnea or show any sign of recurrence by echocardiography during the 2-year follow-up period. PMID:23758983

4. Noninvasive assessment of the stenotic mitral valve orifice by two-dimensional echocardiography

PubMed Central

Jain, Surendra K.; Pechacek, Leonard W.; Decastro, Carlos M.; Garcia, Efrain; Hall, Robert J.

1981-01-01

Two-dimensional echocardiographic imaging of the mitral valve orifice was attempted in 26 patients with isolated mitral stenosis. The intention was to examine further the clinical usefulness and limitations of this technique for estimating the severity of mitral stenosis. Technically adequate recordings of the mitral orifice were obtained in 20 patients (77%). Mitral valve area calculated from echocardiography compared favorably to the valve area derived from cardiac catheterization with the use of the Gorlin formula (r = 0.95). The average difference between the two methods was 0.109 cm2. Two-dimensional echocardiography does provide clinically useful data for predicting the degree of mitral stenosis in the majority of patients provided that critical technical limitations are recognized. Images PMID:15216223

5. A sticky situation: management of spray polyurethane foam insulation in body orifices.

PubMed

Sowerby, Robert J; Sowerby, Leigh J; Vinden, Chris

2011-11-01

Spray polyurethane foam insulation is commonly used in the construction industry to fill gaps, seal, and insulate. We present three cases of intentional spray foam insertion in body orifices and discuss the management of such situations in the emergency department. This series includes a case of oral foam insertion used in a suicide attempt by suffocation and two cases of rectal insertion. All of these cases had potential long-term consequences; one was life-threatening. To our knowledge, this is the first published report on the medical management and removal of foam insulation from body orifices. In all three cases, the foam insulation material was successfully removed after allowing the material to harden.

6. Maximum two-phase flow rates of subcooled nitrogen through a sharp-edged orifice

NASA Technical Reports Server (NTRS)

Simoneau, R. J.

1975-01-01

Data are presented of an experiment in which subcooled liquid nitrogen was discharged through a sharp-edged orifice at flow rates near the maximum. The data covered a range of inlet stagnation pressures from slightly above saturation to twice the thermodynamic critical pressure. The data were taken along five separate inlet stagnation isotherms ranging from 0.75 to 1.035 times the thermodynamic critical temperature. The results indicate that subcooled liquids do not choke or approach maximum flow in an asymptotic manner even though the back pressure is well below saturation; and orifice flow coefficients are not constant as is frequently assumed. A metastable jet appears to exist which breaks down if the difference between back pressure and saturation pressure is large enough.

7. One orifice vein reconstruction in left liver plus caudate lobe grafts.

PubMed

Hashimoto, Takuya; Sugawara, Yasuhiko; Tamura, Sumihito; Kaneko, Junichi; Motomura, Noboru; Takamoto, Shinichi; Makuuchi, Masatoshi

2007-01-27

For maximum use of left liver plus caudate lobe grafts, the short hepatic vein draining the caudate lobe should be reconstructed. We devised a new venoplasty technique. On the graft side, a wide venous orifice with a long cuff was formed by gathering the left, middle, and short hepatic veins using a conduit vein graft and patch vein grafts. On the recipient side, three hepatic veins were connected to make a wide orifice. The liver graft was then connected to the recipient vena cava with a wide outflow tract and a venous reservoir. This new technique was adopted in 12 patients and the short-term results of this technique were satisfactory. The present procedure should simplify venous reconstruction in the recipient and might be useful to prevent hepatic venous stenosis resulting from graft regeneration.

8. Modeling double pulsing of ion beams for HEDP target heating experiments

Veitzer, Seth; Barnard, John; Stoltz, Peter; Henestroza, Enrique

2008-04-01

Recent research on direct drive targets using heavy ion beams suggests optimal coupling will occur when the energy of the ions increases over the course of the pulse. In order to experimentally explore issues involving the interaction of the beam with the outflowing blowoff from the target, double pulse experiments have been proposed whereby a first pulse heats a planar target producing an outflow of material, and a second pulse (˜10 ns later) of higher ion energy (and hence larger projected range) interacts with this outflow before reaching and further heating the target. We report here results for simulations of double pulsing experiments using HYDRA for beam and target parameters relevant to the proposed Neutralized Drift Compression Experiment (NDCX) II at LBNL.

9. On the Resolution Limit of Femtosecond Stimulated Raman Spectroscopy: Modelling Fifth-Order Signals with Overlapping Pulses.

PubMed

Fumero, Giuseppe; Batignani, Giovanni; Dorfman, Konstantin E; Mukamel, Shaul; Scopigno, Tullio

2015-11-16

Femtosecond stimulated Raman scattering (FSRS) spectroscopy is a powerful pump-probe technique that can track electronic and vibrational dynamics with high spectral and temporal resolution. The investigation of extremely short-lived species, however, implies deciphering complex signals and is ultimately hampered by unwanted nonlinear effects once the time resolution limit is approached and the pulses overlap temporally. Using the loop diagrams formalism we calculate the fifth-order response of a model system and address the limiting case where the relevant dynamics timescale is comparable to the pump-pulse duration and, consequently, the pump and the probe overlap temporally. We find that in this regime, additional diagrams that do not contribute for temporally well separated pulses need to be taken into account, giving rise to new time-dependent features, even in the absence of photoinduced dynamics and for negative delays.

10. Combined effects of pre-pulsing and target geometry on efficient EUV production from laser produced plasma experiments and modeling

Hassanein, A.; Sizyuk, T.; Sizyuk, V.; Harilal, S. S.

2011-04-01

Laser produced plasmas (LPP) is currently a promising source of an efficient extreme ultraviolet (EUV) photon source production for advanced lithography. Optimum laser pulse parameters with adjusted wavelength, energy, and duration for simple planar or spherical tin target can provide 2-3% conversion efficiency (CE) in laboratory experiments. These values are also in good agreement with modeling results. Additional effects such as targets with complex geometry and tin-doped targets using pre-pulsing of laser beams can significantly increase CE. Recent studies showed that such improvements in LPP system are due to reduction in laser energy losses by decreasing photons transmission (higher harmonic of Nd:YAG laser) or photons reflection (for CO2 laser). Optimization of target heating using pre-pulses or ablating low-density and nanoporous tin oxide can further improve LLP sources by creating more efficient plasma plumes and as a result increasing CE, the most important parameter for EUV sources. The second important challenge in developing LPP devices is to decrease fast ions and target debris to protect the optical collection system and increase its lifetime. We investigated the combined effects of pre-pulsing with various parameters and different target geometries on EUV conversion efficiency and on energetic ions production. The much higher reflectivity of CO2 laser from a tin target leads to two possible ways for system improvement using pre-pulses with shorter laser wavelengths or using more complex targets geometries with special grooves as developed previously by the authors.

11. Emerging technologies including robotics and natural orifice transluminal endoscopic surgery (NOTES) colorectal surgery.

PubMed

Whiteford, Mark H; Swanstrom, Lee L

2007-12-15

Endoluminal and minimally invasive techniques have a long history and bright future in colorectal surgery. First, we will examine how old (colonoscopy) and new (laparoscopy) techniques combine in the form of laparoscopically assisted colonoscopic polypectomy for removal of "colonoscopically unresectable" colon polyps. Next, we will review the early experiences with robot-assisted minimally invasive colon resections. Lastly, we will introduce the next frontier in minimally invasive surgery, natural orifice transluminal endoscopic surgery (NOTES).

12. A hybrid model for simulation of secondary electron emission in plasma immersion ion implantation under different pulse rise time

SciTech Connect

Navab Safa, N. Ghomi, H.

2015-02-15

A hybrid fluid Particle in Cell–Monte Carlo Collision (PiC–MCC) model is presented to study the effect of secondary electron emission on the plasma immersion ion implantation process under different pulse rise time. The model describes the temporal evolution of various parameters of plasma such as ion density, ion velocity, secondary electron density, and secondary electron current for different rise times. A 3D–3 V PiC–MCC model is developed to simulate the secondary electrons which are emitted from the sample surface while the plasma ions and electrons are treated using a 1D fluid model. The simulation results indicate that the secondary electron density and secondary electron current increase as the rise time decreases. The main differences between the results for different rise times are found during the initial phase of the pulse. The results are explained through studying the fundamental parameters of plasma.

13. Coronal microleakage of three different dental biomaterials as intra-orifice barrier during nonvital bleaching

PubMed Central

Zarenejad, Nafiseh; Asgary, Saeed; Ramazani, Nahid; Haghshenas, Mohammad Reza; Rafiei, Alireza; Ramazani, Mohsen

2015-01-01

Background: This study was designed to assess the microleakage of glass-ionomer (GI), mineral trioxide aggregate (MTA), and calcium-enriched mixture (CEM) cement as coronal orifice barrier during walking bleaching. Materials and Methods: In this experimental study, endodontic treatment was done for 70 extracted human incisors without canal calcification, caries, restoration, resorption, or cracks. The teeth were then divided into three experimental using “Simple randomization allocation” (n = 20) and two control groups (n = 5). The three cements were applied as 3-mm intra-orifice barrier in test groups, and bleaching process was then conducted using a mixture of sodium perborate powder and distilled water, for 9 days. For leakage evaluation, bovine serum albumin marker was traced in a dual-chamber technique with Bradford indicator. The Kruskal-Wallis and Mann-Whitney tests were used for statistical analysis. Results: The mean ± standard deviation leakage of samples from negative control, positive control, GI, MTA, and CEM cement groups were 0.0, 8.9 ± 0.03, 0.47 ± 0.02, 0.48 ± 0.02, and 0.49 ± 0.02 mg/mL, respectively. Statistical analysis showed no significant difference between three experimental groups (P > 0.05). Conclusion: It is concluded that GI, MTA, and CEM cements are considered as suitable intra-orifice barrier to provide coronal seal during walking bleaching. PMID:26759596

14. In vivo microrobots for natural orifice transluminal surgery. Current status and future perspectives.

PubMed

Forgione, A

2009-06-01

The possibility to operate inside the peritoneal cavity through small holes performed in hollow organs that is presented by Natural Orifice Transluminal Endoscopic Surgery (NOTES) represents a major paradigm shift in general surgery. While this new approach seems very appealing from patients' perspectives because it eliminates completely abdominal wall aggression and promises to reduce postoperative pain, it is very challenging for surgeons because of the major constraints imposed by both the mode of access and the limited technology currently available. For this reason NOTES applications at the present time are performed by only a few surgeons and mainly to perform non-complex procedures. While new devices are under development, many of them are trying mainly to simply improve current endoscopic platforms and seem not to offer breakthrough solutions. The numerous challenges introduced by natural orifice approaches require a radical shift in the conception of new technologies in order to make this emerging operative access safe and reproducible. The convergence of several enabling technologies in the field of miniaturization, communication and micro-mechatronics brings the possibility to realize on a large scale the revolutionary concept of miniature in vivo co-operative robots. These robots provide vision and task assistance without the constraints of the entry incision and have been shown in experimental settings to possess many qualities that could be ideal to partner with Natural Orifice Surgery. This article explores the current status of microrobotics as well as presents potential future scenarios of their applications in NOTES.

15. Predicting the backside width of weld pool during pulsed GTAW process based on a neural network model

Zhang, Guangjun; Chen, Shanben; Liu, Xiaodong; Wu, Lin

2001-10-01

Modeling of welding process is the base of process control. Because welding process is a multivariable, strong coupling, time-varying and nonlinear system, traditional modeling methods are not suitable. In this paper, the dynamic neural network model for predicting backside width of pulsed GTAW weld pool by welding parameters and topside shape parameters was constructed. Orthogonal method was applied to design the sampling experiments. Experiments were carried on low carbon steel with 2mm thickness during pulsed gas tungsten arc butt-welding with gap. Based on self-developed vision sensor, double-side images of weld pool were captured simultaneously in a frame. By image processing the topside dimension and shape of weld pool, such as length, maximum width, gap width and the half-length ratio, and the backside dimension such as area, length and maximum width were calculated. Artificial neural network was applied to establish the model for predicting backside width of weld pool. The inputs of the model were the topside dimension, shape of weld pool and welding parameters such as pulse current, pulse duty ratio, and welding speed. The output of the model was the backside width of weld pool. The algorithm was the extended delta-bar-delta (EDD), and the learning ratio automatically determined by the algorithm. Threshold function was sigmoid function. The training cycle was selected to be 50000. The final EMS error of backside width was 5.2 percent. The simulation experiments were carried out to test the accuracy of the ANN model. From the results of the test, the output of ANN model can predict the backside width precisely.

16. A nucleation and growth model of silicon nanoparticles produced by pulsed laser deposition via Monte Carlo simulation

Wang, Yinglong; Qin, Aili; Chu, Lizhi; Deng, Zechao; Ding, Xuecheng; Guan, Li

2017-02-01

We simulated the nucleation and growth of Si nanoparticles produced by pulse laser deposition using Monte Carlo method at the molecular (microscopic) level. In the model, the mechanism and thermodynamic conditions of nucleation and growth of Si nanoparticles were described. In a real physical scale of target-substrate configuration, the model was used to analyze the average size distribution of Si nanoparticles in argon ambient gas and the calculated results are in agreement with the experimental results.

17. Climate-Based Models for Pulsed Resources Improve Predictability of Consumer Population Dynamics: Outbreaks of House Mice in Forest Ecosystems

PubMed Central

Holland, E. Penelope; James, Alex; Ruscoe, Wendy A.; Pech, Roger P.; Byrom, Andrea E.

2015-01-01

Accurate predictions of the timing and magnitude of consumer responses to episodic seeding events (masts) are important for understanding ecosystem dynamics and for managing outbreaks of invasive species generated by masts. While models relating consumer populations to resource fluctuations have been developed successfully for a range of natural and modified ecosystems, a critical gap that needs addressing is better prediction of resource pulses. A recent model used change in summer temperature from one year to the next (ΔT) for predicting masts for forest and grassland plants in New Zealand. We extend this climate-based method in the framework of a model for consumer–resource dynamics to predict invasive house mouse (Mus musculus) outbreaks in forest ecosystems. Compared with previous mast models based on absolute temperature, the ΔT method for predicting masts resulted in an improved model for mouse population dynamics. There was also a threshold effect of ΔT on the likelihood of an outbreak occurring. The improved climate-based method for predicting resource pulses and consumer responses provides a straightforward rule of thumb for determining, with one year’s advance warning, whether management intervention might be required in invaded ecosystems. The approach could be applied to consumer–resource systems worldwide where climatic variables are used to model the size and duration of resource pulses, and may have particular relevance for ecosystems where global change scenarios predict increased variability in climatic events. PMID:25785866

18. Climate-based models for pulsed resources improve predictability of consumer population dynamics: outbreaks of house mice in forest ecosystems.

PubMed

Holland, E Penelope; James, Alex; Ruscoe, Wendy A; Pech, Roger P; Byrom, Andrea E

2015-01-01

Accurate predictions of the timing and magnitude of consumer responses to episodic seeding events (masts) are important for understanding ecosystem dynamics and for managing outbreaks of invasive species generated by masts. While models relating consumer populations to resource fluctuations have been developed successfully for a range of natural and modified ecosystems, a critical gap that needs addressing is better prediction of resource pulses. A recent model used change in summer temperature from one year to the next (ΔT) for predicting masts for forest and grassland plants in New Zealand. We extend this climate-based method in the framework of a model for consumer-resource dynamics to predict invasive house mouse (Mus musculus) outbreaks in forest ecosystems. Compared with previous mast models based on absolute temperature, the ΔT method for predicting masts resulted in an improved model for mouse population dynamics. There was also a threshold effect of ΔT on the likelihood of an outbreak occurring. The improved climate-based method for predicting resource pulses and consumer responses provides a straightforward rule of thumb for determining, with one year's advance warning, whether management intervention might be required in invaded ecosystems. The approach could be applied to consumer-resource systems worldwide where climatic variables are used to model the size and duration of resource pulses, and may have particular relevance for ecosystems where global change scenarios predict increased variability in climatic events.

19. Computational modeling of stress transient and bubble evolution in short-pulse laser irradiated melanosome particles

SciTech Connect

Strauss, M.; Amendt, P.A.; London, R.A.; Maitland, D.J.; Glinsky, M.E.; Lin, C.P.; Kelly, M.W.

1997-03-04

Objective is to study retinal injury by subnanosecond laser pulses absorbed in the retinal pigment epithelium (RPE) cells. The absorption centers in the RPE cell are melanosomes of order 1 {mu}m radius. Each melanosome includes many melanin particles of 10-15 nm radius, which are the local absorbers of the laser light and generate a discrete structure of hot spots. This work use the hydrodynamic code LATIS (LAser-TISsue interaction modeling) and a water equation of state to first simulate the small melanin particle of 15 nm responsible for initiating the hot spot and the pressure field. A average melanosome of 1 {mu}m scale is next simulated. Supersonic shocks and fast vapor bubbles are generated in both cases: the melanin scale and the melanosome scale. The hot spot induces a shock wave pressure than with a uniform deposition of laser energy. It is found that an absorption coefficient of 6000 -8000 cm{sup -1} can explain the enhanced shock wave emitted by the melanosome. An experimental and theoretical effort should be considered to identify the mechanism for generating shock wave enhancement.

20. Femoral perfusion after pulsed electromagnetic field stimulation in a steroid-induced osteonecrosis model.

PubMed

Ikegami, Akira; Ueshima, Keiichiro; Saito, Masazumi; Ikoma, Kazuya; Fujioka, Mikihiro; Hayashi, Shigeki; Ishida, Masashi; Fujiwara, Hiroyoshi; Mazda, Osam; Kubo, Toshikazu

2015-07-01

This study was designed to evaluate femoral perfusion after pulsed electromagnetic field (PEMF) stimulation in a steroid-induced osteonecrosis rabbit model by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Steroid-induced osteonecrosis was produced by single intramuscular injection of methylprednisolone in 15 rabbits. Eight rabbits underwent PEMF stimulation (PEMF group) and seven did not (control group). DCE-MRI was performed before PEMF stimulation, immediately before steroid administration, and 1, 5, 10, and 14 days after steroid administration. Regions of interest were set in the bilateral proximal femora. Enhancement ratio (ER), initial slope (IS), and area under the curve (AUC) were analyzed. ER, IS, and AUC in the control group significantly decreased after steroid administration compared with before administration (P<0.05). In PEMF group, IS significantly decreased; however, ER and AUC showed no significant differences after steroid administration compared with before. ER and IS in PEMF group were higher than in control group until 10th day, and AUC was higher until 5th day after steroid administration (P<0.05). PEMF stimulation restrains the decrease in blood flow after steroid administration.

1. A 1D pulse wave propagation model of the hemodynamics of calf muscle pump function

PubMed Central

Keijsers, J M T; Leguy, C A D; Huberts, W; Narracott, A J; Rittweger, J; van de Vosse, F N

2015-01-01

The calf muscle pump is a mechanism which increases venous return and thereby compensates for the fluid shift towards the lower body during standing. During a muscle contraction, the embedded deep veins collapse and venous return increases. In the subsequent relaxation phase, muscle perfusion increases due to increased perfusion pressure, as the proximal venous valves temporarily reduce the distal venous pressure (shielding). The superficial and deep veins are connected via perforators, which contain valves allowing flow in the superficial-to-deep direction. The aim of this study is to investigate and quantify the physiological mechanisms of the calf muscle pump, including the effect of venous valves, hydrostatic pressure, and the superficial venous system. Using a one-dimensional pulse wave propagation model, a muscle contraction is simulated by increasing the extravascular pressure in the deep venous segments. The hemodynamics are studied in three different configurations: a single artery–vein configuration with and without valves and a more detailed configuration including a superficial vein. Proximal venous valves increase effective venous return by 53% by preventing reflux. Furthermore, the proximal valves shielding function increases perfusion following contraction. Finally, the superficial system aids in maintaining the perfusion during the contraction phase and reduces the refilling time by 37%. © 2015 The Authors. International Journal for Numerical Methods in Biomedical Engineering published by John Wiley & Sons Ltd. PMID:25766693

2. Controlling the temperature of bones using pulsed CO2 lasers: observations and mathematical modeling.

PubMed

Lévesque, Luc; Noël, Jean-Marc; Scott, Calum

2015-12-01

Temperature of porcine bone specimens are investigated by aiming a pulsed CO2 laser beam at the bone-air surface. This method of controlling temperature is believed to be flexible in medical applications as it avoids the uses of thermal devices, which are often cumbersome and generate rather larger temperature variations with time. The control of temperature using this method is modeled by the heat-conduction equation. In this investigation, it is assumed that the energy delivered by the CO2 laser is confined within a very thin surface layer of roughly 9 μm. It is shown that temperature can be maintained at a steady temperature using a CO2 laser and we demonstrate that the method can be adapted to be used in tandem with another laser beam. This method to control the temperature is believed to be useful in de-contamination of bone during the implantation treatment, in bone augmentation when using natural or synthetic materials and in low-level laser therapy.

3. Beverton-Holt discrete pest management models with pulsed chemical control and evolution of pesticide resistance

Liang, Juhua; Tang, Sanyi; Cheke, Robert A.

2016-07-01

Pest resistance to pesticides is usually managed by switching between different types of pesticides. The optimal switching time, which depends on the dynamics of the pest population and on the evolution of the pesticide resistance, is critical. Here we address how the dynamic complexity of the pest population, the development of resistance and the spraying frequency of pulsed chemical control affect optimal switching strategies given different control aims. To do this, we developed novel discrete pest population growth models with both impulsive chemical control and the evolution of pesticide resistance. Strong and weak threshold conditions which guarantee the extinction of the pest population, based on the threshold values of the analytical formula for the optimal switching time, were derived. Further, we addressed switching strategies in the light of chosen economic injury levels. Moreover, the effects of the complex dynamical behaviour of the pest population on the pesticide switching times were also studied. The pesticide application period, the evolution of pesticide resistance and the dynamic complexity of the pest population may result in complex outbreak patterns, with consequent effects on the pesticide switching strategies.

4. Modeling of photocurrent kinetics upon pulsed photoexcitation of photosynthetic proteins: a case of bacteriorhodopsin.

PubMed

Kuo, Chia-Ling; Chu, Li-Kang

2014-10-01

The proton pump of bacteriorhodopsin in an aqueous solution at varied pH upon pulsed excitation was monitored using a solution-based electrochemical module. The photocurrent action spectrum agreed with the absorption contour at 495-645 nm. Diminishing the photocurrent amplitude by adding a protonophore, carbonyl cyanide m-chlorophenyl hydrazone, revealed that protons were the charge carriers of the photocurrent. The evolution of the conventional proton pump is proposed to occur in three elementary steps consecutively: first, the proton relay from the protonated Schiff base to the purple membrane (PM) surface (k1), then the proton exchange between PM surface and bulk (k2), and finally, the proton uptake (k3). The fitted temporal profiles of the photocurrent agreed with observations in the pH range 5.8-9.5. At pH 7.3, k1, k2, and k3 were 2098 s(-1), 412 s(-1), and 44 s(-1), respectively. The rate coefficients at pH 9.5 were smaller than those at pH 6.3 by a factor of approximately 2, consistent with the differences in the intrinsic mobilities of the charge carriers proton and hydroxide ion. The combination of the electrochemical detection module and the concomitant model provides a promising tool for quantitative and qualitative characterization of the light-driven ion pumps.

5. Methods on handling missing rainfall data with Neyman-Scott rectangular pulse modeling

Yendra, Rado; Jemain, Abdul Aziz; Zahari, Marina; Wan Zin, Wan Zawiah

2013-04-01

Rainfall data from rain-gauge stations suffers the risk of being missing due to factors such as human negligence, faulty equipment and disasters. In this paper, complete monthly rainfall data from 1985 to 1992 in Payakangsar station is used as the base data to determine the appropriate method for handling missing data. A portion of this complete data is then omitted at random by as much as 5%, 10% and 15% of the total number of data. Three methods of missing data replacement are considered that is, replacement of the missing data with zero (NR), single imputation (SI) and multiple imputation (MI) methods. The Neyman-Scott Rectangular Pulse (NSRP) rainfall stochastic model is then fitted to the resulting data from these three methods. Data from the month of October and November are selected for further analysis as these two months represent the months with highest rainfall amount received. To assess the performance of these three methods, a goodness-of-fit test based on the mean absolute error is applied. Results from the goodness-of-fit test indicate that NR method is the best for each case of missing data in the month of October, and also for the 5% case in November. On the other hand, method of imputation with 4 stages (MI) is superior for cases of 10% and 15% in November.

6. Size distributions of fly ash using Coulter Multisizer: Use of multiple orifices and fitting to truncated log-normal distributions

SciTech Connect

Ghosal, S.; Ebert, J.L.; Self, S.A.

1991-11-01

Fly ash particles, which are predominantly spherical and glassy, are produced by melting of the mineral inclusions in the coal during combustion. Particle diameters can range from sub-micrometer (micron or {mu}m) to greater than 100 {mu}m. The size distribution of fly ash is needed to determine its role in the radiation transfer process in pulverized coal combustors. The Coulter Multisizer is an useful instrument for sizing powders with a broad size distribution. A single Multisizer orifice can size particles only within a specific size range limited at the lower end to a few percent of orifice diameter by sensitivity and at the upper end by increasing non-linearity of the signal-volume relation. A scheme for combining data obtained using orifices of different diameters is described. The manufacturers state that the smallest particle which can be sized accurately is nominally 2% of the diameter of the orifice. However, it was found that the data for particles less than 4% of the orifice diameter were not reliable. In order to use the smaller orifices, the larger particles have to be removed from the sample. A wet-sieving apparatus, designed for accurate separation of the particles by size, is described. A log-normal distribution function, truncated outside the measurement limits, fits the size distribution data well. Size parameters for fly ashes of six representative US coals are presented.

7. A theoretical study of the acoustic impedance of orifices in the presence of a steady grazing flow

NASA Technical Reports Server (NTRS)

Rice, E. J.

1976-01-01

An analysis of the oscillatory fluid flow in the vicinity of a circular orifice with a steady grazing flow is presented. The study is similar to that of Hersh and Rogers but with the addition of the grazing flow. Starting from the momentum and continuity equations, a considerably simplified system of partial differential equations is developed with the assumption that the flow can be described by an oscillatory motion superimposed upon the known steady flow. The equations are seen to be linear in the region where the grazing flow effects are dominant, and a solution and the resulting orifice impedance are presented for this region. The nonlinearity appears to be unimportant for the usual conditions found in aircraft noise suppressors. Some preliminary conclusions of the study are that orifice resistance is directly proportional to grazing flow velocity (known previously from experimental data) and that the orifice inductive (mass reactance) end correction is not a function of grazing flow. This latter conclusion is contrary to the widely held notion that grazing flow removes the effect of the orifice inductive end correction. This conclusion also implies that the experimentally observed total inductance reduction with grazing flow might be in the flow within the orifice rather than in the end correction.

8. Mixing of Multiple Jets With a Confined Subsonic Crossflow. Part 2; Opposed Rows of Orifices in Rectangular Ducts

NASA Technical Reports Server (NTRS)

Holdeman, James D.; Liscinsky, David S.; Bain, Daniel B.

1997-01-01

This paper summarizes experimental and computational results on the mixing of opposed rows of jets with a confined subsonic crossflow in rectangular ducts. The studies from which these results were excerpted investigated flow and geometric variations typical of the complex 3-D flowfield in the combustion chambers in gas turbine engines. The principal observation was that the momentum-flux ratio, J, and the orifice spacing, S/H, were the most significant flow and geometric variables. Jet penetration was critical, and penetration decreased as either momentum-flux ratio or orifice spacing decreased. It also appeared that jet penetration remained similar with variations in orifice size, shape, spacing, and momentum-flux ratio when the orifice spacing was inversely proportional to the square-root of the momentum-flux ratio. It was also seen that planar averages must be considered in context with the distributions. Note also that the mass-flow ratios and the offices investigated were often very large (jet-to-mainstream mass-flow ratio greater than 1 and the ratio of orifices-area-to-mainstream-cross-sectional-area up to 0.5 respectively), and the axial planes of interest were often just downstream of the orifice trailing edge. Three-dimensional flow was a key part of efficient mixing and was observed for all configurations.

9. One-dimensional model for the intracranial pulse morphological analysis during hyperventilation and CO2 inhalation tests

Ryu, Jaiyoung; Hu, Xiao; Shadden, Shawn C.

2015-11-01

The brain's CO2 reactivity mechanism is coupled with cerebral autoregulation and other unique features of cerebral hemodynamics. We developed a one-dimensional nonlinear model of blood flow in the cerebral arteries coupled to lumped parameter (LP) networks. The LP networks incorporate cerebral autoregulation, CO2 reactivity, intracranial pressure, cerebrospinal fluid, and cortical collateral blood flow models. The model was used to evaluate hemodynamic variables (arterial deformation, blood velocity and pressure) in the cerebral vasculature during hyperventilation and CO2 inhalation test. Tests were performed for various arterial blood pressure (ABP) representing normal and hypotensive conditions. The increase of the cerebral blood flow rates agreed well with the published measurements for various ABP measurements taken during clinical CO2 reactivity tests. The changes in distal vasculature affected the reflected pulse wave energy, which caused the waveform morphological changes at the middle cerebral, common and internal carotid arteries. The pulse morphological analysis demonstrated agreement with previous clinical measurements for cerebral vasoconstriction and vasodilation.

10. Numerical Modeling and Testing of an Inductively-Driven and High-Energy Pulsed Plasma Thrusters

NASA Technical Reports Server (NTRS)

Parma, Brian

2004-01-01

Pulsed Plasma Thrusters (PPTs) are advanced electric space propulsion devices that are characterized by simplicity and robustness. They suffer, however, from low thrust efficiencies. This summer, two approaches to improve the thrust efficiency of PPTs will be investigated through both numerical modeling and experimental testing. The first approach, an inductively-driven PPT, uses a double-ignition circuit to fire two PPTs in succession. This effectively changes the PPTs configuration from an LRC circuit to an LR circuit. The LR circuit is expected to provide better impedance matching and improving the efficiency of the energy transfer to the plasma. An added benefit of the LR circuit is an exponential decay of the current, whereas a traditional PPT s under damped LRC circuit experiences the characteristic "ringing" of its current. The exponential decay may provide improved lifetime and sustained electromagnetic acceleration. The second approach, a high-energy PPT, is a traditional PPT with a variable size capacitor bank. This PPT will be simulated and tested at energy levels between 100 and 450 joules in order to investigate the relationship between efficiency and energy level. Arbitrary Coordinate Hydromagnetic (MACH2) code is used. The MACH2 code, designed by the Center for Plasma Theory and Computation at the Air Force Research Laboratory, has been used to gain insight into a variety of plasma problems, including electric plasma thrusters. The goals for this summer include numerical predictions of performance for both the inductively-driven PPT and high-energy PFT, experimental validation of the numerical models, and numerical optimization of the designs. These goals will be met through numerical and experimental investigation of the PPTs current waveforms, mass loss (or ablation), and impulse bit characteristics.

11. Computer modeling of electrical and thermal performance during bipolar pulsed radiofrequency for pain relief

SciTech Connect

Pérez, Juan J.; Pérez-Cajaraville, Juan J.; Muñoz, Víctor; Berjano, Enrique

2014-07-15

Purpose: Pulsed RF (PRF) is a nonablative technique for treating neuropathic pain. Bipolar PRF application is currently aimed at creating a “strip lesion” to connect the electrode tips; however, the electrical and thermal performance during bipolar PRF is currently unknown. The objective of this paper was to study the temperature and electric field distributions during bipolar PRF. Methods: The authors developed computer models to study temperature and electric field distributions during bipolar PRF and to assess the possible ablative thermal effect caused by the accumulated temperature spikes, along with any possible electroporation effects caused by the electrical field. The authors also modeled the bipolar ablative mode, known as bipolar Continuous Radiofrequency (CRF), in order to compare both techniques. Results: There were important differences between CRF and PRF in terms of electrical and thermal performance. In bipolar CRF: (1) the initial temperature of the tissue impacts on temperature progress and hence on the thermal lesion dimension; and (2) at 37 °C, 6-min of bipolar CRF creates a strip thermal lesion between the electrodes when these are separated by a distance of up to 20 mm. In bipolar PRF: (1) an interelectrode distance shorter than 5 mm produces thermal damage (i.e., ablative effect) in the intervening tissue after 6 min of bipolar RF; and (2) the possible electroporation effect (electric fields higher than 150 kV m{sup −1}) would be exclusively circumscribed to a very small zone of tissue around the electrode tip. Conclusions: The results suggest that (1) the clinical parameters considered to be suitable for bipolar CRF should not necessarily be considered valid for bipolar PRF, and vice versa; and (2) the ablative effect of the CRF mode is mainly due to its much greater level of delivered energy than is the case in PRF, and therefore at same applied energy levels, CRF, and PRF are expected to result in same outcomes in terms of

12. Investigations of Acoustics and Heat Transfer Characteristics of Thermoacoustic Driven Pulse Tube Refrigerators

Bretagne, E.; François, M.-X.; Ishikawa, H.

2004-06-01

The purpose of this article is to investigate the design of the ThermoAcoustic Driven Pulse Tube Refrigerator which is a promising solution for large scale pulse tube applications. Designing concepts and preliminary studies of heat transfer in heat exchangers specifically for large scale TADPTR are presented. Thus, we introduce the way to deal with different components of the Pulse Tube Refrigerator to achieve the most efficient regenerator operation with the constraints imposed by the thermoacoustic driver. The main building-concepts are illustrated by considering the combinations of a standing wave Thermoacoustic prime mover with (i) an Inertance-Orifice PTR and (ii) a Lumped Boost PTR. Both experimental and numerical results support the models. Furthermore, we investigate the heat transfer mechanism for Reynolds number between 104 to 2×105 in helium. For the current experiment, measurements are taken at the cold heat exchanger of the prime mover. For the purpose of the analysis we select testing conditions so that the particle displacement is larger than the heat exchanger length and the boundary layer assumption applies. Adequacy of the steady flow assumption is discussed. Nusselt number obtained from the measurements is then correlated with a function of Prandtl, Reynolds and Valensi numbers.

13. A Superfluid Pulse Tube Refrigerator Without Moving Parts for Sub-Kelvin Cooling

NASA Technical Reports Server (NTRS)

Miller, Franklin K.

2012-01-01

A report describes a pulse tube refrigerator that uses a mixture of He-3 and superfluid He-4 to cool to temperatures below 300 mK, while rejecting heat at temperatures up to 1.7 K. The refrigerator is driven by a novel thermodynamically reversible pump that is capable of pumping the He-3 He-4 mixture without the need for moving parts. The refrigerator consists of a reversible thermal magnetic pump module, two warm heat exchangers, a recuperative heat exchanger, two cold heat exchangers, two pulse tubes, and an orifice. It is two superfluid pulse tubes that run 180 out of phase. All components of this machine except the reversible thermal pump have been demonstrated at least as proof-of-concept physical models in previous superfluid Stirling cycle machines. The pump consists of two canisters packed with pieces of gadolinium gallium garnet (GGG). The canisters are connected by a superleak (a porous piece of VYCOR glass). A superconducting magnetic coil surrounds each of the canisters.

14. Pulse wave analysis in a 180-degree curved artery model: Implications under physiological and non-physiological inflows

Bulusu, Kartik V.; Plesniak, Michael W.

2013-11-01

Systolic and diastolic blood pressures, pulse pressures, and left ventricular hypertrophy contribute to cardiovascular risks. Increase of arterial stiffness due to aging and hypertension is an important factor in cardiovascular, chronic kidney and end-stage-renal-diseases. Pulse wave analysis (PWA) based on arterial pressure wave characteristics, is well established in clinical practice for evaluation of arterial distensibility and hypertension. The objective of our exploratory study in a rigid 180-degree curved artery model was to evaluate arterial pressure waveforms. Bend upstream conditions were measured using a two-component, two-dimensional, particle image velocimeter (2C-2D PIV). An ultrasonic transit-time flow meter and a catheter with a MEMS-based solid state pressure sensor, capable of measuring up to 20 harmonics of the observed pressure waveform, monitored flow conditions downstream of the bend. Our novel continuous wavelet transform algorithm (PIVlet 1.2), in addition to detecting coherent secondary flow structures is used to evaluate arterial pulse wave characteristics subjected to physiological and non-physiological inflows. Results of this study will elucidate the utility of wavelet transforms in arterial function evaluation and pulse wave speed. Supported by NSF Grant No. CBET- 0828903 and GW Center for Biomimetics and Bioinspired Engineering.

15. Downscaling transient climate change using a Neyman-Scott Rectangular Pulses stochastic rainfall model

Burton, A.; Fowler, H. J.; Blenkinsop, S.; Kilsby, C. G.

2010-02-01

SummaryThe future management of hydrological systems must be informed by climate change projections at relevant time horizons and at appropriate spatial scales. Furthermore, the robustness of such management decisions is dependent on both the uncertainty inherent in future climate change scenarios and the natural climate system. Addressing these needs, we present a new transient rainfall simulation methodology which combines dynamical and statistical downscaling techniques to produce transient (i.e. temporally non-stationary) climate change scenarios. This is used to generate a transient multi-model ensemble of simulated point-scale rainfall time series for 1997-2085 for the polluted Brévilles spring in Northern France. The recovery of this previously potable source may be affected by climatic changes and variability over the next few decades. The provision of locally-relevant transient climate change scenarios for use as input to hydrological models of both water quality and quantity will ultimately provide a valuable resource for planning and decision making. Observed rainfall from 1988-2006 was characterised in terms of a set of statistics for each calendar month: the daily mean, variance, probability dry, lag-1 autocorrelation and skew, and the monthly variance. The Neyman-Scott Rectangular Pulses (NSRP) stochastic rainfall model was fitted to these observed statistics and correctly simulated both monthly statistics and extreme rainfall properties. Multiplicative change factors which quantify the change in each statistic between the periods 1961-1990 and 2071-2100 were estimated for each month and for each of 13 Regional Climate Models (RCMs) from the PRUDENCE ensemble. To produce transient climate change scenarios, pattern scaling factors were estimated and interpolated from four time-slice integrations of two General Circulation Models which condition the RCMs, ECHAM4/OPYC and HadCM3. Applying both factors to the observed statistics provided projected

16. Numerical Modelling and Simulation of Chemical Reactions in a Nano-Pulse Discharged Bubble for Water Treatment

He, Yuchen; Satoshi, Uehara; Hidemasa, Takana; Hideya, Nishiyama

2016-09-01

A zero-dimensional model to simulate a nano-pulse-discharged bubble in water was developed. The model consists of gas and liquid phases corresponding to the inside and outside of the bubble, respectively. The diffusions of chemical species from the gas to the liquid phase through the bubble interface was also investigated. The initial gas is Ar, but includes a little H2O and O2 in the bubble. The time evolution of the OH concentration in the liquid phase was mainly investigated as an important species for water treatment. It was shown that OH was generated in the bubble and then diffused into the liquid. With the application of a continuous nano-pulse discharge, more OH radicals were generated as the frequency increased at a low voltage for a given power consumption. supported partially by Japan Society for the Promotion of Science (JSPS) KAKENHI (No. 26249015)

17. Pulse transit time variability analysis in an animal model of endotoxic shock.

PubMed

Tang, Collin H H; Chan, Gregory S H; Middleton, Paul M; Cave, Grant; Harvey, Martyn; Javed, Faizan; Savkin, Andrey V; Lovell, Nigel H

2010-01-01

The use of non-invasively measured pulse transit time (PTT) to monitor the cardiovascular systems in critically ill patients, like sepsis, can be of significant clinical value. In this study, the potential of PTT and its variability in cardiovascular system monitoring in a mechanically ventilated and anesthetized rabbit model of endotoxic shock was assessed. Eight adult New Zealand white rabbits, which were treated with endotoxin bolus infusion, were studied. Measurements of PTT, pre-ejection period (PEP), and vascular transit time (VTT) were obtained in pre- and post-intervention stages (before and 90 minutes after the administration of endotoxin). The decrease in mean PTT (p < 0.05) and PEP (p < 0.01) in the post-intervention stage reflected sympathetic activation, whilst the increase in respiratory variation in PTT (p < 0.01), PEP (p 〈 0.01), and VTT (p < 0.01) could be attributed to an enhancement of respiratory variation in stroke volume associated with hypovolemia in endotoxic shock. The relationship between beat-to-beat variability in PTT and all other cardiovascular time series were further investigated through linear regression analysis, which revealed that PTT was most strongly correlated with VTT (R(2) ≥ 0.84 with positive slope). Computation of coherence and phase shift in the ventilating frequency band (HF: 0.50 - 0.75 Hz) showed that the respiratory variation in PTT was synchronized with both PEP and VTT (coherence > 0.84 with phase shift less than one cardiac beat). These results highlighted the potential value of PTT and its respiratory variation in characterizing the pathophysioloigcal hemodynamic change in endotoxic shock.

18. Modeling of high efficiency solar cells under laser pulse for power beaming applications

NASA Technical Reports Server (NTRS)

Jain, Raj K.; Landis, Geoffrey A.

1994-01-01

Solar cells have been used to convert sunlight to electrical energy for many years and also offer great potential for non-solar energy conversion applications. Their greatly improved performance under monochromatic light compared to sunlight, makes them suitable as photovoltaic (PV) receivers in laser power beaming applications. Laser beamed power to a PV array receiver could provide power to satellites, an orbital transfer vehicle, or a lunar base. Gallium arsenide (GaAs) and indium phosphide (InP) solar cells have calculated efficiencies of more than 50 percent under continuous illumination at the optimum wavelength. Currently high power free-electron lasers are being developed which operate in pulsed conditions. Understanding cell behavior under a laser pulse is important in the selection of the solar cell material and the laser. An experiment by NAsA lewis and JPL at the AVLIS laser facility in Livermore, CA presented experimental data on cell performance under pulsed laser illumination. Reference 5 contains an overview of technical issues concerning the use of solar cells for laser power conversion, written before the experiments were performed. As the experimental results showed, the actual effects of pulsed operation are more complicated. Reference 6 discusses simulations of the output of GaAs concentrator solar cells under pulsed laser illumination. The present paper continues this work, and compares the output of Si and GaAs solar cells.

19. Modeling of high efficiency solar cells under laser pulse for power beaming applications

Jain, Raj K.; Landis, Geoffrey A.

1994-09-01

Solar cells have been used to convert sunlight to electrical energy for many years and also offer great potential for non-solar energy conversion applications. Their greatly improved performance under monochromatic light compared to sunlight, makes them suitable as photovoltaic (PV) receivers in laser power beaming applications. Laser beamed power to a PV array receiver could provide power to satellites, an orbital transfer vehicle, or a lunar base. Gallium arsenide (GaAs) and indium phosphide (InP) solar cells have calculated efficiencies of more than 50 percent under continuous illumination at the optimum wavelength. Currently high power free-electron lasers are being developed which operate in pulsed conditions. Understanding cell behavior under a laser pulse is important in the selection of the solar cell material and the laser. An experiment by NAsA lewis and JPL at the AVLIS laser facility in Livermore, CA presented experimental data on cell performance under pulsed laser illumination. Reference 5 contains an overview of technical issues concerning the use of solar cells for laser power conversion, written before the experiments were performed. As the experimental results showed, the actual effects of pulsed operation are more complicated. Reference 6 discusses simulations of the output of GaAs concentrator solar cells under pulsed laser illumination. The present paper continues this work, and compares the output of Si and GaAs solar cells.

20. A spatial model with pulsed releases to compare strategies for the sterile insect technique applied to the mosquito Aedes aegypti.

PubMed

Oléron Evans, Thomas P; Bishop, Steven R

2014-08-01

We present a simple mathematical model to replicate the key features of the sterile insect technique (SIT) for controlling pest species, with particular reference to the mosquito Aedes aegypti, the main vector of dengue fever. The model differs from the majority of those studied previously in that it is simultaneously spatially explicit and involves pulsed, rather than continuous, sterile insect releases. The spatially uniform equilibria of the model are identified and analysed. Simulations are performed to analyse the impact of varying the number of release sites, the interval between pulsed releases and the overall volume of sterile insect releases on the effectiveness of SIT programmes. Results show that, given a fixed volume of available sterile insects, increasing the number of release sites and the frequency of releases increases the effectiveness of SIT programmes. It is also observed that programmes may become completely ineffective if the interval between pulsed releases is greater that a certain threshold value and that, beyond a certain point, increasing the overall volume of sterile insects released does not improve the effectiveness of SIT. It is also noted that insect dispersal drives a rapid recolonisation of areas in which the species has been eradicated and we argue that understanding the density dependent mortality of released insects is necessary to develop efficient, cost-effective SIT programmes.

1. Experimental study of mechanical response of artificial tissue models irradiated with Nd:YAG nanosecond laser pulses

Pérez-Gutiérrez, Francisco G.; Camacho-López, Santiago; Aguilar, Guillermo

2011-07-01

Nanosecond long laser pulses are used in medical applications where precise tissue ablation with minimal thermal and mechanical collateral damage is required. When a laser pulse is incident on a material, optical energy will be absorbed by a combination of linear and nonlinear absorption according to both: laser light irradiance and material properties. In the case of water or gels, the first results in heat generation and thermoelastic expansion; while the second results in an expanding plasma formation that launches a shock wave and a cavitation/boiling bubble. Plasma formation due to nonlinear absorption of nanosecond laser pulses is originated by a combination of multiphoton ionization and thermionic emission of free electrons, which is enhanced when the material has high linear absorption coefficient. In this work, we present three experimental approaches to study pressure transients originated when 6 ns laser pulses are incident on agar gels and water with varying linear absorption coefficient, using laser radiant exposures above and below threshold for bubble formation: (a) PVDF sensors, (b) Time-resolved shadowgraphy and (c) Time-resolved interferometry. The underlying hypothesis is that pressure transients are composed of the superposition of both: shock wave originated by hot expanding plasma resulting from nonlinear absorption of optical energy and, thermoelastic expansion originated by heat generation due to linear absorption of optical energy. The objective of this study is to carry out a comprehensive experimental analysis of the mechanical effects that result when tissue models are irradiated with nanosecond laser pulses to elucidate the relative contribution of linear and nonlinear absorption to bubble formation. Furthermore, we investigate cavitation bubble formation with temperature increments as low as 3 °C.

2. Pulsed electric fields for burn wound disinfection in a murine model.

PubMed

Golberg, Alexander; Broelsch, G Felix; Vecchio, Daniela; Khan, Saiqa; Hamblin, Michael R; Austen, William G; Sheridan, Robert L; Yarmush, Martin L

2015-01-01

Emerging bacterial resistance renders many antibiotics ineffective, making alternative strategies of wound disinfection important. Here the authors report on a new, physical burn wound disinfection method: pulsed electric fields (PEFs). High voltage, short PEFs create nonthermal, permanent damage to cell membranes, possibly by irreversible electroporation. In medicine, PEF technology has recently been used for nonthermal ablation of solid tumors. The authors have expanded the spectrum of PEF applications in medicine to burn wound disinfection. A third-degree burn was induced on the dorsal skin of C57BL/6 mice. Immediately after the injury, the burn wound was infected with Acinetobacter baumannii expressing the luxCDABE operon. Thirty minutes after infection, the infected areas were treated with 80 pulses delivered at 500 V/mm, 70 μs, 1 Hz. The authors used bioluminescence to quantify bacteria on skin. Three animals were used for each experimental condition. PEFs were effective in the disinfection of infected burned murine skin. The bacterial load reduction correlated with the number of delivered pulses. Forty pulses of 500 V/mm led to a 2.04 ± 0.29 Log10 reduction in bacterial load; 80 pulses led to the immediate 5.53 ± 0.30 Log10 reduction. Three hours after PEF, the bacterial reduction of the skin treated with 500 V/mm, 80 pulses was 4.91 ± 0.71 Log10. The authors introduce a new method of wound disinfection using high voltage, short PEFs. They believe that PEF technology may represent an important alternative to antibiotics in addressing bacterial contamination of wounds, particularly those contaminated with multidrug-resistant bacteria.

3. Pulsed Electric Fields for Burn Wound Disinfection in a Murine Model

PubMed Central

Golberg, Alexander; Broelsch, G. Felix; Vecchio, Daniela; Khan, Saiqa; Hamblin, Michael R.; Austen, William G.; Sheridan, Robert L.; Yarmush, Martin L.

2014-01-01

Emerging bacterial resistance renders many antibiotics ineffective, making alternative strategies of wound disinfection important. Here the authors report on a new, physical burn wound disinfection method: pulsed electric fields (PEFs). High voltage, short PEFs create nonthermal, permanent damage to cell membranes, possibly by irreversible electroporation. In medicine, PEF technology has recently been used for nonthermal ablation of solid tumors. The authors have expanded the spectrum of PEF applications in medicine to burn wound disinfection. A third-degree burn was induced on the dorsal skin of C57BL/6 mice. Immediately after the injury, the burn wound was infected with Acinetobacter baumannii expressing the luxCDABE operon. Thirty minutes after infection, the infected areas were treated with 80 pulses delivered at 500 V/mm, 70 μs, 1 Hz. The authors used bioluminescence to quantify bacteria on skin. Three animals were used for each experimental condition. PEFs were effective in the disinfection of infected burned murine skin. The bacterial load reduction correlated with the number of delivered pulses. Forty pulses of 500 V/mm led to a 2.04 ± 0.29 Log10 reduction in bacterial load; 80 pulses led to the immediate 5.53 ± 0.30 Log10 reduction. Three hours after PEF, the bacterial reduction of the skin treated with 500 V/mm, 80 pulses was 4.91 ± 0.71 Log10. The authors introduce a new method of wound disinfection using high voltage, short PEFs. They believe that PEF technology may represent an important alternative to antibiotics in addressing bacterial contamination of wounds, particularly those contaminated with multidrug-resistant bacteria. PMID:25167374

4. Monte Carlo modeling and analyses of YALINA- booster subcritical assembly Part II : pulsed neutron source.

SciTech Connect

Talamo, A.; Gohar, M. Y. A.; Rabiti, C.; Nuclear Engineering Division

2008-10-22

One of the most reliable experimental methods for measuring the kinetic parameters of a subcritical assembly is the Sjoestrand method applied to the reaction rate generated from a pulsed neutron source. This study developed a new analytical methodology for characterizing the kinetic parameters of a subcritical assembly using the Sjoestrand method, which allows comparing the analytical and experimental time dependent reaction rates and the reactivity measurements. In this methodology, the reaction rate, detector response, is calculated due to a single neutron pulse using MCNP/MCNPX computer code or any other neutron transport code that explicitly simulates the fission delayed neutrons. The calculation simulates a single neutron pulse over a long time period until the delayed neutron contribution to the reaction is vanished. The obtained reaction rate is superimposed to itself, with respect to the time, to simulate the repeated pulse operation until the asymptotic level of the reaction rate, set by the delayed neutrons, is achieved. The superimposition of the pulse to itself was calculated by a simple C computer program. A parallel version of the C program is used due to the large amount of data being processed, e.g. by the Message Passing Interface (MPI). The new calculation methodology has shown an excellent agreement with the experimental results available from the YALINA-Booster facility of Belarus. The facility has been driven by a Deuterium-Deuterium or Deuterium-Tritium pulsed neutron source and the (n,p) reaction rate has been experimentally measured by a {sup 3}He detector. The MCNP calculation has utilized the weight window and delayed neutron biasing variance reduction techniques since the detector volume is small compared to the assembly volume. Finally, this methodology was used to calculate the IAEA benchmark of the YALINA-Booster experiment.

5. An engineering model to simulate the thermal response of electronic devices during pulsed Nd:YAG laser welding

SciTech Connect

Gianoulakis, S.E.; Voth, T.E.; Fuerschbach, P.W.; Prinzbach, J.H.

1996-12-31

A model is developed to predict the thermal response of real electronic devices during pulsed Nd:YAG laser welding. Modeling laser-part interaction requires incorporation of weld pool hydrodynamics, and laser-metal vapor and laser-surface interactions. Although important information can be obtained from these models, they are not appropriate for use in design of actual components due to computational limitations. In lieu of solving for these detailed physics, a simple model is constructed. In this model, laser-part interactions are accounted for through an empirically determined energy transfer efficiency which is developed through the use of modeling and experiments. This engineering model is appropriate since part thermal response near the weld pool and weld pool shape is not of interest here. Reasonable agreement between predictions and experimental measurements for welding of real components are indicated.

6. An efficient two-dimensional ALE modelling and experimental validation for pulsed laser-matter interaction

Zhao, Qiang; Dong, Zhiwei

2016-11-01

We have developed two-dimensional Arbitrary Lagrangian Eulerian (ALE) code which is used to study the physical processes, the plasma absorption, the crater profile, and the temperature distribution on metallic target and below the surface. The ALE method overcomes problems with Lagrangian moving mesh distortion by mesh smoothing and conservative quantities remapping from Lagrangian mesh to smoothed one. The results of numerical simulation of pulsed laser ablation are presented. The study presents particular interest for the analysis of experimental results obtained during pulsed laser ablation.

7. Modelling the relationship between peripheral blood pressure and blood volume pulses using linear and neural network system identification techniques.

PubMed

Allen, J; Murray, A

1999-08-01

The relationships between peripheral blood pressure and blood volume pulse waveforms can provide valuable physiological data about the peripheral vascular system, and are the subject of this study. Blood pressure and volume pulse waveforms were collected from 12 normal male subjects using non-invasive optical techniques, finger arterial blood pressure (BP, Finapres: Datex-Ohmeda) and photoelectric plethysmography (PPG) respectively, and captured to computer for three equal (1 min) measurement phases: baseline, hand raising and hand elevated. This simple physiological challenge was designed to induce a significant drop in peripheral blood pressure. A simple first order lag transfer function was chosen to study the relationship between blood pressure (system input) and blood volume pulse waveforms (system output), with parameters describing the dynamics (time constant, tau) and input-output gain (K). Tau and K were estimated for each subject using two different system identification techniques: a recursive parameter estimation algorithm which calculated tau and K from a linear auto-regressive with exogenous variable (ARX) model, and an artificial neural network which was trained to learn the non-linear process input-output relationships and then derive a linearized ARX model of the system. The identification techniques allowed the relationship between the blood pressure and blood volume pulses to be described simply, with the neural network technique providing a better model fit overall (p < 0.05, Wilcoxon). The median falls in tau following the hand raise challenge were 26% and 31% for the linear and neural network based techniques respectively (both p < 0.05, Wilcoxon). This preliminary study has shown that the time constant and gain parameters obtained using these techniques can provide physiological data for the clinical assessment of the peripheral circulation.

8. Performance of a High-Speed Compression-Ignition Engine Using Multiple Orifice Fuel Injection Nozzles

NASA Technical Reports Server (NTRS)

Spanogle, J A; Foster, H H

1930-01-01

This report presents test results obtained at the Langley Memorial Aeronautical Laboratory of the National Advisory Committee for Aeronautics during an investigation to determine the relative performance of a single-cylinder, high-speed, compression-ignition engine when using fuel injection valve nozzles with different numbers, sizes, and directions of round orifices. A spring-loaded, automatic injection valve was used, centrally located at the top of a vertical disk-type combustion chamber formed between horizontally opposed inlet and exhaust valves of a 5 inch by 7 inch engine.

9. Double-Orifice Mitral Valve in an Eight-Year-Old Boy.

PubMed

Segreto, Antonio; De Salvatore, Sergio; Chiusaroli, Alessandro; Bizzarri, Federico; Van Wyk, Cornelius; Congiu, Stefano

2015-07-01

The case is described of an eight-year-old boy who required an operation for moderate mitral regurgitation due to a double-orifice mitral valve (DOMV). The DOMV, which was clearly demonstrated by transthoracic echocardiography, had a central fibrous bridge. Mitral valve repair using a 5/0 Prolene suture placed at the level of the superior commissure of each hole to stabilize the valve, and ring annuloplasty with Edwards Physio ring, was successfully performed. Intraoperative real-time transesophageal echocardiography showed the repaired DOMV to be without regurgitation or stenosis.

10. [Thermoelastic excitation of acoustic waves in biological models under the effect of the high peak-power pulsed electromagnetic radiation of extremely high frequency].

PubMed

Gapeev, A B; Rubanik, A V; Pashovkin, T N; Chemeris, N K

2007-01-01

The capability of high peak-power pulsed electromagnetic radiation of extremely high frequency (35,27 GHz, pulse widths of 100 and 600 ns, peak power of 20 kW) to excite acoustic waves in model water-containing objects and muscular tissue of animals has been experimentally shown for the first time. The amplitude and duration of excited acoustic pulses are within the limits of accuracy of theoretical assessments and have a complex nonlinear dependence on the energy input of electromagnetic radiation supplied. The velocity of propagation of acoustic pulses in water-containing models and isolated muscular tissue of animals was close to the reference data. The excitation of acoustic waves in biological systems under the action of high peak-power pulsed electromagnetic radiation of extremely high frequency is the important phenomenon, which essentially contributes to the understanding of the mechanisms of biological effects of these electromagnetic fields.

11. Self-consistent fluid modeling and simulation on a pulsed microwave atmospheric-pressure argon plasma jet

SciTech Connect

Chen, Zhaoquan; Yin, Zhixiang Chen, Minggong; Hong, Lingli; Hu, Yelin; Huang, Yourui; Xia, Guangqing; Liu, Minghai; Kudryavtsev, A. A.

2014-10-21

In present study, a pulsed lower-power microwave-driven atmospheric-pressure argon plasma jet has been introduced with the type of coaxial transmission line resonator. The plasma jet plume is with room air temperature, even can be directly touched by human body without any hot harm. In order to study ionization process of the proposed plasma jet, a self-consistent hybrid fluid model is constructed in which Maxwell's equations are solved numerically by finite-difference time-domain method and a fluid model is used to study the characteristics of argon plasma evolution. With a Guass type input power function, the spatio-temporal distributions of the electron density, the electron temperature, the electric field, and the absorbed power density have been simulated, respectively. The simulation results suggest that the peak values of the electron temperature and the electric field are synchronous with the input pulsed microwave power but the maximum quantities of the electron density and the absorbed power density are lagged to the microwave power excitation. In addition, the pulsed plasma jet excited by the local enhanced electric field of surface plasmon polaritons should be the discharge mechanism of the proposed plasma jet.

12. A multi-scale, hierarchial model of pulse dynamics in arid-land ecosystems

Technology Transfer Automated Retrieval System (TEKTRAN)

Ecological processes in aridlands are often described by the pulse-reserve paradigm where rain events drive biological activity until moisture is depleted leaving a reserve. This paradigm is frequently applied to processes stimulated by one or a few rainfall events within a growing season. Here we e...

13. A new model for the aerobic metabolism of yeast allows the detailed analysis of the metabolic regulation during glucose pulse.

PubMed

Kesten, Duygu; Kummer, Ursula; Sahle, Sven; Hübner, Katrin

2015-11-01

The onset of aerobic fermentation (the so-called Crabtree effect) in yeast has long been of interest. However, the underlying mechanisms at the metabolic level are not yet fully understood. We developed a detailed kinetic model of the aerobic central metabolism of Saccharomyces cerevisiae comprising glycolysis, TCA cycle and major transport reactions across the mitochondrial membrane to investigate this phenomenon. It is the first one of this extent in the literature. The model is able to reproduce experimental steady state fluxes and time-course behavior after a glucose pulse. Due to the lack of parameter identifiability in the model, we analyze a model ensemble consisting of a set of differently parameterized models for robust findings. The model predicts that the cooperativity of pyruvate decarboxylase with respect to pyruvate and the capacity difference between alcohol dehydrogenase and the pyruvate dehydrogenase bypass play a major role for the onset of the Crabtree effect.

14. Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP).

PubMed

Moon, Hui-Sung; Kwon, Kiho; Kim, Seung-Il; Han, Hyunju; Sohn, Joohyuk; Lee, Soohyeon; Jung, Hyo-Il

2011-03-21

Circulating tumor cells (CTCs) are highly correlated with the invasive behavior of cancer, so their isolations and quantifications are important for biomedical applications such as cancer prognosis and measuring the responses to drug treatments. In this paper, we present the development of a microfluidic device for the separation of CTCs from blood cells based on the physical properties of cells. For use as a CTC model, we successfully separated human breast cancer cells (MCF-7) from a spiked blood cell sample by combining multi-orifice flow fractionation (MOFF) and dielectrophoretic (DEP) cell separation technique. Hydrodynamic separation takes advantage of the massive and high-throughput filtration of blood cells as it can accommodate a very high flow rate. DEP separation plays a role in precise post-processing to enhance the efficiency of the separation. The serial combination of these two different sorting techniques enabled high-speed continuous flow-through separation without labeling. We observed up to a 162-fold increase in MCF-7 cells at a 126 µL min(-1) flow rate. Red and white blood cells were efficiently removed with separation efficiencies of 99.24% and 94.23% respectively. Therefore, we suggest that our system could be used for separation and detection of CTCs from blood cells for biomedical applications.

15. Comparison of Gas Displacement based on Thermometry in the Pulse Tube with Rayleigh Scattering

Hagiwara, Yasumasa; Nara, Kenichi; Ito, Seitoku; Saito, Takamoto

A pulse tube refrigerator has high reliability because of its simple structure. Recently the level of development activity of the pulse tube refrigerator has increased, but the quantitative understanding of the refrigeration mechanism has not fully been obtained. Therefore various explanations were proposed. The concept of virtual gas piston in particular helps us to understand the function of a phase shifter such as a buffer tank and an orifice because the virtual gas piston corresponds to a piston of a Stirling refrigerator. However it is difficult to directly measure the averaged gas displacement which corresponds to the virtual gas piston because uniform gas flow such as a gas piston does not always exist. For example, there are a jet flow from orifice and circulated flows in a pulse tube, which are predicted theoretically. In spite of these phenomena, the averaged gas displacement is very important in practical use because it can simply predict the performance from the displacement. In this report, we calculate the averaged gas displacement and mass flow through an orifice. The mass flow is calculated from the pressure change in a buffer tank. The averaged gas displacement is calculated from temperature profiles in the pulse tube and the mass flow. It is necessary to measure temperature in the pulse tube as widely as possible in order to calculate the averaged gas displacement. We apply a method using the Rayleigh Scattering the thermometry in the pulse tube. With this method, it is possible to perform 2-dimensional measurement without disturbing the gas flow. By this method, the averaged gas displacements and the temperature profiles of basic and orifice types of refrigeration were compared.

16. Development of artificial model of caval syndrome in canine heartworm disease.

PubMed

Kitagawa, H; Sasaki, Y; Ishihara, K; Kuwahara, Y

1990-10-01

In order to develop an artificial model of caval syndrome (dirofilarial hemoglobinuria), heartworm-like silicone tubes were inserted into the tricuspid valve orifice and right atrium of dogs. Fifteen to 25 tubes with some knots were inserted through the posterior vena cava in 6 dogs (knot-tube group), 7 to 12 tubes without knot (small-number group) through the jugular vein in another 5 dogs, or 25 to 35 tubes (large-number group) in yet another 5 dogs. The tubes remained in the right atrium, and a part of them protruded into the tricuspid valve orifice. The number of tubes at the tricuspid valve orifice was the greatest in the large-number group. After tube insertion, the signs of so-called "caval syndrome", such as systolic cardiac murmur, jugular pulse, anemia, and so on, were observed in almost all cases of the 3 groups, the signs were severest in the large-number group. Urine hemoglobin was detected in almost all cases of the knot-tube and large-number groups, and in 1 case in the small-number group. Ascites was observed in 1 case of the knot-tube group at 6 weeks, in 1 case of the small-number group at 7 days and in 3 cases of the large-number group at 7 days after insertion.

17. Effects of Pressure Fluctuation on Flow-Accelerated Corrosion in the Downstream of Orifice Nozzle

Shakouchi, Toshihiko; Suzuki, Takayuki; Kugimoto, Mitsuo; Tsujimoto, Koichi; Ando, Toshitake

In the piping system of power plants, pipe wall thinning caused by flow-accelerated corrosion (FAC), liquid droplet impingement (LDI) erosion, and cavitation Erosion (C/E), is a very serious problem because it leads to serious damage and eventual destruction of the piping system [1]-[6]. In this study, pipe wall thinning caused by FAC in the downstream of an orifice nozzle (flow meter) was examined. Experimental Analyses were performed to clarify the characteristics of FAC, its generation mechanism, and the prediction of the thinning and reduction of the pipe wall. The corrosion pattern on the pipe wall was also examined through an experimental simulation. This simulation clarified that the occurrence of thinning mainly depend on the amount of pressure fluctuation p' on the pipe wall. It was also found that the wall thinning rate can be estimated using p' and that the suppression of p' can be realized by replacing the orifice nozzle with a tapered one having an angle to the upstream.

18. Increasing the stability of nanofluids with cavitating flows in micro orifices

Karimzadehkhouei, Mehrdad; Ghorbani, Morteza; Sezen, Meltem; Şendur, Kürşat; Pınar Mengüç, M.; Leblebici, Yusuf; Koşar, Ali

2016-09-01

One of the most critical challenges for nanofluids in practical applications is related to their stability and reusability since a gradual agglomeration of nanoparticles in nanofluids occurs with time and is accelerated by heating. In this study, we propose a technique to maintain the performance and stability of nanofluids with the use of cavitating flows through micro orifices to prevent agglomeration and sedimentation of nanoparticles, which will increase the durability of the nanofluids. γ-Al2O3 (gamma-alumina) nanoparticles with a mean diameter of 20 nm suspended in water were utilized. In the current approach, a flow restrictive element induces sudden pressure, which leads to cavitation bubbles downstream from the orifice. The emerging bubbles interact with the agglomerated structure of nanoparticles and decrease its size through hitting or shock waves generated by their collapse, thereby increasing the stability and reusability of nanofluids. The method does not involve any use of expensive surfactants or surface modifiers, which might alter the thermophysical properties of nanofluids, may adversely influence their performance and biocompatibility, and may limit their effectiveness.

19. New trends in colorectal surgery: single port and natural orifice techniques.

PubMed

Daher, Ronald; Chouillard, Elie; Panis, Yves

2014-12-28

Single-incision laparoscopic surgery (SILS) and natural orifice transluminal endoscopic surgery (NOTES) have rapidly gained pace worldwide, potentially replacing conventional laparoscopic surgery (CLS) as the preferred colorectal surgery technique. Currently available data mainly consist of retrospective series analyzed in four meta-analyses. Despite conflicting results and lack of an objective comparison, SILS appears to offer cosmetic advantages over CLS. However, due to conflicting results and marked heterogeneity, present data fail to show significant differences in terms of operative time, postoperative morbidity profiles, port-site complications rates, oncological appropriateness, duration of hospitalization or cost when comparing SILS with conventional laparoscopy for colorectal procedures. The application of "pure" NOTES in humans remains limited to case reports because of unresolved issues concerning the ideal access site, distant organ reach, spatial orientation and viscera closure. Alternatively, minilaparoscopy-assisted natural orifice surgery techniques are being developed. The transanal "down-to-up" total mesorectum excision has been derived for transanal endoscopic microsurgery (TEM) and represents the most encouraging NOTES-derived technique. Preliminary experiences demonstrate good oncological and functional short-term outcomes. Large-scale randomized controlled trials are now mandatory to confirm the long-term SILS results and validate transanal TEM for the application of NOTES in humans.

20. Experimental study of cooling performance of pneumatic synthetic jet with singular slot rectangular orifice

Yu, Roger Ho Zhen; Ismail, Mohd Azmi bin; Ramdan, Muhammad Iftishah; Mustaffa, Nur Musfirah binti

2017-03-01

Synthetic Jet generates turbulence flow in cooling the microelectronic devices. In this paper, the experiment investigation of the cooling performance of pneumatic synthetic jet with single slot rectangular orifices at low frequency motion is presented. The velocity profile at the end of the orifice was measured and used as characteristic performance of synthetic jet in the present study. Frequencies of synthetic jet and the compressed air pressure supplied to the pneumatic cylinder (1bar to 5bar) were the parameters of the flow measurement. The air velocity of the synthetic jet was measured by using anemometer air flow meter. The maximum air velocity was 0.5 m/s and it occurred at frequency motion of 8 Hz. The optimum compressed air supplied pressure of the synthetic jet study was 4 bar. The cooling performance of synthetic jet at several driven frequencies from 0 Hz to 8 Hz and heat dissipation between 2.5W and 9W were also investigate in the present study. The results showed that the Nusselt number increased and thermal resistance decreased with both frequency and Reynolds number. The lowest thermal resistance was 5.25°C/W and the highest Nusselt number was 13.39 at heat dissipation of 9W and driven frequency of 8Hz.

1. Unguarded tricuspid orifice with pulmonary atresia: successful radiofrequency ablation of an accessory pathway in an infant

PubMed Central

Magee, A.; Rosenthal, E.; Bostock, J.; Gill, J.

1998-01-01

A male infant with the rare lesion of unguarded tricuspid orifice in the setting of pulmonary valve atresia, intact ventricular septum, and a hypoplastic right ventricle is described. The patient presented with cyanosis at 1 day old; transcutaneous oxygen saturations were between 20% and 30% in room air, and 60% in 100% inspired oxygen. Pre-excitation was found incidentally on the ECG and the potential for rapid antegrade conduction of atrial tachyarrhythmias, after eventual extended palliation with the Fontan procedure, was demonstrated at electrophysiological study. By 11 months old the patient was becoming increasingly cyanosed and interim palliation with a bidirectional cavopulmonary shunt was proposed. Successful radiofrequency ablation of the accessory pathway was performed before bidirectional cavopulmonary shunt, which would have prevented access to the heart via the superior vena cava. Difficulty with femoral venous access because of previous occlusion of a femoral vein was overcome by the use of 2 F pacing electrodes and a 5 F ablation catheter.   Keywords: radiofrequency ablation;  accessory pathway;  unguarded tricuspid orifice PMID:9505931

2. Development of a Haptic Interface for Natural Orifice Translumenal Endoscopic Surgery Simulation

PubMed Central

Dargar, Saurabh; Sankaranarayanan, Ganesh

2016-01-01

Natural orifice translumenal endoscopic surgery (NOTES) is a minimally invasive procedure, which utilizes the body’s natural orifices to gain access to the peritoneal cavity. The NOTES procedure is designed to minimize external scarring and patient trauma, however flexible endoscopy based pure NOTES procedures require critical scope handling skills. The delicate nature of the NOTES procedure requires extensive training, thus to improve access to training while reducing risk to patients we have designed and developed the VTEST©, a virtual reality NOTES simulator. As part of the simulator, a novel decoupled 2-DOF haptic device was developed to provide realistic force feedback to the user in training. A series of experiments were performed to determine the behavioral characteristics of the device. The device was found capable of rendering up to 5.62N and 0.190Nm of continuous force and torque in the translational and rotational DOF, respectively. The device possesses 18.1Hz and 5.7Hz of force bandwidth in the translational and rotational DOF, respectively. A feedforward friction compensator was also successfully implemented to minimize the negative impact of friction during the interaction with the device. In this work we have presented the detailed development and evaluation of the haptic device for the VTEST©. PMID:27008674

3. Observation of Gas-Liquid Flow Near the Exit Orifice of An Effervescent Atomizer

Sun, C. H.; Ning, Z.; Lü, M.; Fu, J.; Li, Y. X.

For deepen the understanding of the mechanism of effervescent atomization: it is necessary to have a better observation on the gas-liquid flow near the exit orifice. Both image and acoustic ways were introduced to observe the gas-fluid flow by a transparent effervescent atomizer. The results show that: It can be clearly seen from images that internal flow regimes make great influence on the spray behavior. Spray acoustic observation is an effective way to grasp the gas-liquid two phases flow behavior when they ejecting from the exit orifice. The acoustic analyzing in time and frequency domain has the ability to obtain the discrete phenomenon existing in effervescent sprays, in thus way, acoustic features could give a new perspective on effervescent spray over time. What's more, the discrete phenomenon in dilute bubbly flow and slug flow can be easily captured from after acoustic analyzing. Uniform two-phase distribution of internal flow shows continues acoustic performance after observing the homogeneous bubbly flow and chum flow.

4. Development of a Haptic Interface for Natural Orifice Translumenal Endoscopic Surgery Simulation.

PubMed

Dargar, Saurabh; De, Suvranu; Sankaranarayanan, Ganesh

2016-01-01

Natural orifice translumenal endoscopic surgery (NOTES) is a minimally invasive procedure, which utilizes the body's natural orifices to gain access to the peritoneal cavity. The NOTES procedure is designed to minimize external scarring and patient trauma, however flexible endoscopy based pure NOTES procedures require critical scope handling skills. The delicate nature of the NOTES procedure requires extensive training. Thus, to improve access to training while reducing risk to patients, we have designed and developed the VTEST, a virtual reality NOTES simulator. As part of the simulator, a novel decoupled 2-DOF haptic device was developed to provide realistic force feedback to the user in training. A series of experiments were performed to determine the behavioral characteristics of the device. The device was found capable of rendering up to 5.62N and 0.190 Nm of continuous force and torque in the translational and rotational DOF, respectively. The device possesses 18.1 and 5.7 Hz of force bandwidth in the translational and rotational DOF, respectively. A feedforward friction compensator was also successfully implemented to minimize the negative impact of friction during the interaction with the device. In this work, we have presented the detailed development and evaluation of the haptic device for the VTEST.

5. Enzymolysis kinetics, thermodynamics and model of porcine cerebral protein with single-frequency countercurrent and pulsed ultrasound-assisted processing.

PubMed

Zou, Ye; Ding, Yangyang; Feng, Weiwei; Wang, Wei; Li, Qian; Chen, Yao; Wu, Huiyu; Wang, Xintong; Yang, Liuqing; Wu, Xiangyang

2016-01-01

The present work investigated the enzymolysis kinetics, thermodynamics and model of porcine cerebral protein (PCP) which was pretreated by single-frequency countercurrent and pulsed ultrasound. The kinetic constants for ultrasonic pretreated and traditional enzymolysis have been determined. Results showed that the value of KM in ultrasonic PCP (UPCP) enzymolysis decreased by 9% over that in the traditional enzymolysis. The values of reaction rate constant (k) for UPCP enzymolysis increased by 207%, 121%, 62%, and 45% at 293, 303, 313 and 323 K, respectively. For the thermodynamic parameters, ultrasound decreased activation energy (Ea), change in enthalpy (ΔH) and entropy (ΔS) by 76%, 82% and 31% in PCP, respectively. However, ultrasound had little change in Gibbs free energy (ΔG) value in the temperature range of 293-323 K. Therefore, a general kinetic equation for the enzymolysis model of UPCP by a simple empirical equation was suggested. The experimental values fits with the enzymolysis kinetic model with a low average relative error (4%) confirmed that the kinetic model was accurate to reflect the enzymolysis process. The positive effect of single-frequency countercurrent and pulsed ultrasound in this study and application of the kinetic model may be useful for the release of bioactive peptides from meat processing by-products.

6. LIGHT SCATTERING: Axial and diffusion models of the laser pulse propagation in a highly-scattering medium

Tereshchenko, Sergei A.; Danilov, Arsenii A.; Podgaetskii, Vitalii M.; Vorob'ev, Nikolai S.

2004-06-01

The propagation of laser radiation through a layer of a highly-scattering medium (HSM) is considered on the basis of two theoretical models: a nonstationary axial (two-flux) model and a nonstationary diffusion model. Analytic expressions for the temporal distributions of the photons of an ultrashort laser pulse transmitted through the HSM are presented. Experimental temporal distributions are used to obtain the parameters of models corresponding to an HSM, to determine the theoretical temporal distributions, and to compare them with the experimental curves. These two theoretical models are compared quantitatively for the first time. Their advantages and drawbacks that must be considered in the development of HSM transmission optical tomography are pointed out.

7. Encircling isolation of pulmonary vein orifice for elimination of persistent atrial fibrillation associated with mitral valve disease.

PubMed

Matsumoto, Yasushi; Watanabe, Go; Endo, Masamitsu; Sasaki, Hisao; Kasashima, Fuminori

2003-01-01

The authors treated a 70-year-old woman with persistent atrial fibrillation associated with mitral valve stenosis. Restoration of sinus rhythm was achieved with encircling isolation of pulmonary vein orifices concomitant with mitral valve replacement. A vertical incision in the right side of left atrium was extended to the margin of the upper and lower left pulmonary vein orifices. Supplemental cryo-coagulation was applied to the remnant of the circular incision, avoiding the entire encircling incision. Consequently, all pulmonary veins were electrically isolated. Encircling pulmonary vein orifice isolation is less invasive than the MAZE procedure because of reductions in surgical time and cardiopulmonary bypass time, minimization of atrial incisions, and prevention of injury to the coronary artery. It is thus an effective option for selected patients with atrial fibrillation.

8. Pulse Oximetry

MedlinePlus

... www.thoracic.org amount of gases (oxygen and carbon dioxide) that are in your blood. To get ... Also, a pulse oximeter does not measure your carbon dioxide level. How accurate is the pulse oximeter? ...

9. Effect of vehicle configuration on the performance of a submersible pulsed-jet vehicle at intermediate Reynolds number.

PubMed

Nichols, J Tyler; Krueger, Paul S

2012-09-01

Recent results have demonstrated that pulsed-jet propulsion can achieve propulsive efficiency greater than that for steady jets when short, high frequency pulses are used, and the pulsed-jet advantage increases as Reynolds number decreases into the intermediate range (∼50). An important aspect of propulsive performance, however, is the vehicle configuration. The nozzle configuration influences the jet speed and, in the case of pulsed-jets, the formation of the vortex rings with each jet pulse, which have important effects on thrust. Likewise, the hull configuration influences the vehicle speed through its effect on drag. To investigate these effects, several flow inlet, nozzle, and hull tail configurations were tested on a submersible, self-propelled pulsed-jet vehicle ('Robosquid' for short) for jet pulse length-to-diameter ratios (L/D) in the range 0.5-6 and pulsing duty cycles (St(L)) of 0.2 and 0.5. For the configurations tested, the vehicle Reynolds number (Re(υ)) ranged from 25 to 110. In terms of propulsive efficiency, changing between forward and aft-facing inlets had little effect for the conditions considered, but changing from a smoothly tapered aft hull section to a blunt tail increased propulsive efficiency slightly due to reduced drag for the blunt tail at intermediate Re(υ). Sharp edged orifices also showed increased vehicle velocity and propulsive efficiency in comparison to smooth nozzles, which was associated with stronger vortex rings being produced by the flow contraction through the orifice. Larger diameter orifices showed additional gains in propulsive efficiency over smaller orifices if the rate of mass flow was matched with the smaller diameter cases, but using the same maximum jet velocity with the larger diameter decreased the propulsive efficiency relative to the smaller diameter cases.

10. Does Pulsed Magnetic Field Therapy Influence Nerve Regeneration in the Median Nerve Model of the Rat?

PubMed Central

Beck-Broichsitter, Benedicta E.; Lamia, Androniki; Fregnan, Federica; Smeets, Ralf; Becker, Stephan T.; Sinis, Nektarios

2014-01-01

The aim of this study was to evaluate the impact of pulsed magnetic field therapy on peripheral nerve regeneration after median nerve injury and primary coaptation in the rat. Both median nerves were surgically exposed and denervated in 24 female Wistar rats. A microsurgical coaptation was performed on the right side, whereas on the left side a spontaneous healing was prevented. The study group underwent a daily pulsed magnetic field therapy; the other group served as a control group. The grasping force was recorded 2 weeks after the surgical intervention for a period of 12 weeks. The right median nerve was excised and histologically examined. The histomorphometric data and the functional assessments were analyzed by t-test statistics and one-way ANOVA. One-way ANOVA indicated a statistically significant influence of group affiliation and grasping force (P = 0.0078). Grasping strength was higher on a significant level in the experimental group compared to the control group permanently from the 9th week to the end of the study. T-test statistics revealed a significantly higher weight of the flexor digitorum sublimis muscle (P = 0.0385) in the experimental group. The histological evaluation did not reveal any statistically significant differences concerning the histomorphometric parameters. Our results suggest that the pulsed magnetic field therapy has a positive influence on the functional aspects of neural regeneration. More studies are needed to precisely evaluate and optimize the intensity and duration of the application. PMID:25143937

11. Accurate modeling of antennas for radiating short pulses, FDTD analysis and experimental measurements

Maloney, James G.; Smith, Glenn S.

1993-01-01

Antennas used to radiate short pulses often require different design rules that those that are used to radiate essentially time-harmonic signals. The finite-difference time-domain (FDTD) method is a very flexible numerical approach that can be used to treat a variety of electromagnetic problems in the time domain. It is well suited to the analysis and design of antennas for radiating short pulses; however, several advances had to be made before the method could be applied to this problem. In this paper, we will illustrate the use of the FDTD method with two antennas designed for the radiation of short pulses. The first is a simple, two-dimensional geometry, and open-ended parallel-plate waveguide, while the second is a three-dimensional, rotationally symmetric geometry, a conical monopole fed through an image by a coaxial transmission line. Both antennas are 'optimized' according to given criteria by adjusting geometrical parameters and including resistive loading that varies continuously with position along the antenna. The predicted performance for the conical monopole antenna is compared with experimental measurements; this verifies the optimization and demonstrates the practicality of the design.

12. Modelling the interaction between the plasma and the neutral gas in a pulsed glow discharge in nitrogen

SciTech Connect

Guiberteau, E.; Bonhomme, G.; Zoheir, C.

1995-12-31

We present here the first results obtained from the modelling of a pulsed glow discharge in nitrogen, taking into account the heat transfer to the neutral gas. The aim of modelling is to optimize the plasma process in a nitriding reactor. The iron sample to be nitrided forms the cathode of the glow discharge at low pressure (100 to 200 Pa). The reactor uses two disks of diameter 50 mm as electrodes with a 40 mm gap. It works in a pulsed regime (cycle period varies from 10 to 100 ms) with a discharge duration which can be varied from 0.5 to 10 ms. Experimental studies have been carried out using emission spectroscopy resolved in space (1 mm) and time (1 {mu}s), under various discharge and post-discharge durations. These studies have shown the important effect of energy transfer from the discharge to the neutral gas. In fact this transfer produces an expansion of the negative glow observed when the post-discharge duration is decreased. A realistic modelling should thus be performed bearing in mind that the neutral gas behaves not as a thermostat. Consequently the thermal and hydrodynamic evolution of the neutral gas must be considered in the whole modelling.

13. Noncircular Orifice Holes and Advanced Fabrication Techniques for Liquid Rocket Injectors (Phases 1, 2, 3, and 4)

NASA Technical Reports Server (NTRS)

Mchale, R. M.; Nurick, W. H.

1974-01-01

A comprehensive summary of the results of a cold-flow and hot-fire experimental study of the mixing and atomization characteristics of injector elements incorporating noncircular orifices is presented. Both liquid/liquid and gas/liquid element types are discussed. Unlike doublet and triplet elements (circular orifices only) were investigated for the liquid/liquid case while concentric tube elements were investigated for the gas/liquid case. It is concluded that noncircular shape can be employed to significant advantage in injector design for liquid rocket engines.

14. Self-consistent particle-in-cell modelling of short pulse absorption and transport for high energy density physics experiments

Ramsay, M. G.; Arber, T. D.; Sircombe, N. J.

2016-03-01

In order for detailed, solid density particle-in-cell (PIC) simulations to run within a reasonable time frame, novel approaches to modelling high density material must be employed. For the purposes of modelling high intensity, short pulse laser-plasma interactions, however, these approaches must be consistent with retaining a full PIC model in the low-density laser interaction region. By replacing the standard Maxwell field solver with an electric field update based on a simplified Ohm's law in regions of high electron density, it is possible to access densities at and above solid without being subject to the standard grid and time step constraints. Such a model has recently been implemented in the PIC code EPOCH. We present the initial results of a detailed two-dimensional simulation performed to compare the adapted version of the code with recent experimental results from the Orion laser facility.

15. Quantifying the Length and Variance of the Eukaryotic Cell Cycle Phases by a Stochastic Model and Dual Nucleoside Pulse Labelling

PubMed Central

Weber, Tom Serge; Jaehnert, Irene; Schichor, Christian; Or-Guil, Michal; Carneiro, Jorge

2014-01-01

A fundamental property of cell populations is their growth rate as well as the time needed for cell division and its variance. The eukaryotic cell cycle progresses in an ordered sequence through the phases and and is regulated by environmental cues and by intracellular checkpoints. Reflecting this regulatory complexity, the length of each phase varies considerably in different kinds of cells but also among genetically and morphologically indistinguishable cells. This article addresses the question of how to describe and quantify the mean and variance of the cell cycle phase lengths. A phase-resolved cell cycle model is introduced assuming that phase completion times are distributed as delayed exponential functions, capturing the observations that each realization of a cycle phase is variable in length and requires a minimal time. In this model, the total cell cycle length is distributed as a delayed hypoexponential function that closely reproduces empirical distributions. Analytic solutions are derived for the proportions of cells in each cycle phase in a population growing under balanced growth and under specific non-stationary conditions. These solutions are then adapted to describe conventional cell cycle kinetic assays based on pulse labelling with nucleoside analogs. The model fits well to data obtained with two distinct proliferating cell lines labelled with a single bromodeoxiuridine pulse. However, whereas mean lengths are precisely estimated for all phases, the respective variances remain uncertain. To overcome this limitation, a redesigned experimental protocol is derived and validated in silico. The novelty is the timing of two consecutive pulses with distinct nucleosides that enables accurate and precise estimation of both the mean and the variance of the length of all phases. The proposed methodology to quantify the phase length distributions gives results potentially equivalent to those obtained with modern phase-specific biosensor-based fluorescent

16. Dynamic of a delayed predator-prey model with birth pulse and impulsive harvesting in a polluted environment

Wang, Xiaohong; Jia, Jianwen

2015-03-01

In this paper, we propose a delayed predator-prey model with birth pulse and impulsive harvesting in a polluted environment. Existence conditions of the predator-extinction periodic solution are derived by developing the discrete dynamical system, which is determined by the stroboscopic map. Further, we discuss the global attractivity of predator-extinction periodic solution and permanence of the system, and obtain the threshold conditions. The results provide a dependable theoretical strategies to protect population from extinction in a polluted environment. Finally, the numerical simulations are presented for verifying the theoretical conclusions.

17. An analytical model for pulse shape and electrothermal stability in two-body transition-edge sensor microcalorimeters

SciTech Connect

Bennett, D. A.; Horansky, R. D.; Schmidt, D. R.; Swetz, D. S.; Vale, L. R.; Ullom, J. N.; Hoover, A. S.; Hoteling, N. J.; Rabin, M. W.

2010-09-06

High-resolution superconducting gamma-ray sensors show potential for the more accurate analysis of nuclear material. These devices are part of a larger class of microcalorimeters and bolometers based on transition edge sensors (TESs) that have two distinct thermal bodies. We derive the time domain behavior of the current and temperature for compound TES devices in the small signal limit and demonstrate the utility of these equations for device design and characterization. In particular, we use the model to fit pulses from our gamma-ray microcalorimeters and demonstrate how critical damping and electrothermal stability can be predicted.

18. Template Reproduction of GRB Pulse Light Curves

Hakkila, Jon E.; Preece, R. D.; Loredo, T. J.; Wolpert, R. L.; Broadbent, M. E.

2014-01-01

A study of well-isolated pulses in gamma ray burst light curves indicates that simple models having smooth and monotonic pulse rises and decays are inadequate. Departures from the Norris et al. (2005) pulse shape are in the form of a wave-like pre-peak residual that is mirrored and stretched following the peak. Pulse shape departures are present in GRB pulses of all durations, but placement of the departures relative to pulse peaks correlates with asymmetry. This establishes an additional link between temporal structure and spectral evolution, as pulse asymmetry is related to initial hardness while pulse duration indicates the rate of hard-to-soft pulse evolution.

19. Physical Parameters, Modeling, and Methodological Details in Using IR Laser Pulses to Warm Frozen or Vitrified Cells Ultra-Rapidly†

PubMed Central

Kleinhans, F.W.; Mazur, Peter

2015-01-01

We report additional details of the thermal modeling, selection of the laser, and construction of the Cryo Jig used for our ultra-rapid warming studies of mouse oocytes (B Jin, FW Kleinhans, Peter Mazur, Cryobiology 68 (2014) 419–430). A Nd:YAG laser operating at 1064 nm was selected to deliver short 1 msec pulses of sufficient power to produce a warming rate of 1 × 107 °C/min from –190°C to 0°C. A special Cryo Jig was designed and built to rapidly remove the sample from LN2 and expose it to the laser pulse. India ink carbon black particles were required to increase the laser energy absorption of the sample. The thermal model reported here is more general than that previously reported. The modeling reveals that the maximum warming rate achievable via external warming across the cell membrane is proportional to (1/R2) where R is the cell radius. PMID:25724528

20. Foliation-Based Parameter Tuning in a Model of the GnRH Pulse and Surge Generator

Clement, Frederique; Vidal, Alexandre

2009-01-01

We investigate a model of the GnRH pulse and surge generator, with the definite aim of constraining the model GnRH output with respect to a physiologically relevant list of specifications. The alternating pulse and surge pattern of secretion results from the interaction between a GnRH secreting system and a regulating system exhibiting slow-fast dynamics. The mechanisms underlying the behavior of the model are reviewed from the study of the Boundary-Layer System according to the dissection method principle. Using singular perturbation theory, we describe the sequence of bifurcations undergone by the regulating (FitzHugh-Nagumo) system, encompassing the rarely investigated case of homoclinic connection. Based on pure dynamical considerations, we restrict the space of parameter search for the regulating system and describe a foliation of this restricted space, whose leaves define constant duration ratios between the surge and the pulsatility phase in the whole system. We propose an algorithm to fix the parameter values also to meet the other prescribed ratios dealing with amplitude and frequency features of the secretion signal. We finally apply these results to illustrate the dynamics of GnRH secretion in the ovine species and the rhesus monkey.

1. PULSE GENERATOR

DOEpatents

Roeschke, C.W.

1957-09-24

An improvement in pulse generators is described by which there are produced pulses of a duration from about 1 to 10 microseconds with a truly flat top and extremely rapid rise and fall. The pulses are produced by triggering from a separate input or by modifying the current to operate as a free-running pulse generator. In its broad aspect, the disclosed pulse generator comprises a first tube with an anode capacitor and grid circuit which controls the firing; a second tube series connected in the cathode circuit of the first tube such that discharge of the first tube places a voltage across it as the leading edge of the desired pulse; and an integrator circuit from the plate across the grid of the second tube to control the discharge time of the second tube, determining the pulse length.

2. Analytical Modeling of Transport Aircraft Crash Scenarios to Obtain Floor Pulses.

DTIC Science & Technology

1983-04-01

airplane design , airportIoff-runway hazards and accident avoidance procedures 1-5 1-3 Transportation fatalities, 1980-81 1-6 1-4 Trend of accidents rates...4.5:1.5 loading (test no. 10) condition 9-15 9-11 Potential improved body block design 9-16 9-12 Dynamic response factor curves for triangular pulse 9...significant. The following grouping is possible: 0 Airplane Design Related - accidents which occur around airports; i.e., on the runway or within 350 a

3. In vivo assessment of number of milk duct orifices in lactating women and association with parameters in the mother and the infant

PubMed Central

2014-01-01

Background In vitro and in vivo analyses differ between the number of milk ducts found in the lactating breast, and there is a lack of knowledge as to whether or not external factors in the mother or the child affect the number of ductal orifices. The aim of this study was to determine the number of milk duct orifices in vivo and to investigate the possible influence of variable parameters in mother and infant. Methods Study design: Prospective clinical trial. In 98 breastfeeding women we investigated the nipple surface in order to identify the number of milk duct orifices using Marmet’s manual milk expression technique. In addition mothers were interviewed on different parameters of birth and breastfeeding. Results Every nipple had 3.90 ± 1.48 milk duct orifices on average. There was no significant difference between left and right breasts. The use of a breast pump in addition to breastfeeding did not have any effect on the number of ductal orifices. Multiparous women exhibited more ductal orifices (8.5 ± 3.0) as compared to primipara (7.1 ± 2.7). Boys were associated with significantly more ductal orifices in their mother’s right breast (4.2 ± 1.7) than girls (3.5 ± 1.4). Furthermore boys were breastfed for longer per session. A shorter birth height of males correlated with more ductal orifices in left nipples. Fluid intake of mothers was associated with a higher number of ductal orifices. Restless infant behavior could not be explained by less milk duct orifices. Pain in the breast during breastfeeding did not have an influence on ductal orifices either. Psychological criteria, such as duration of maternity leave and total intended breastfeeding period, did not affect the number of orifices in the papilla mammaria of breasts during lactation. Conclusion For the first time an in vivo investigation of the number of ductal orifices in lactating women was conducted non-invasively and associations with variables in the mother and the

4. [Appendiceal orifice inflammation in distal ulcerative colitis. Report of a case and review of the literature].

PubMed

Tagle, Martin; Scavino, Yolanda; Luna, Eduardo

2010-01-01

We report the case of a 45-year-old female patient with an 18 month diagnosis of distal ulcerative colitis (proctosigmoiditis) of 18 months, who presented initially with allergy to salicylates, for which the disease was managed with corticosteroids and azathioprine and subsequently with Infliximab infusions, entering in remission. When she was about to receive her fifth Infliximab infusion she presented an exacerbation of her underlying disease with frequent stools with mucus, blood and tenesmus. Given that her initial diagnosis was made with a sigmoidoscopy we scheduled a total colonoscopy showing marked inflammation, erythema and friability limited to the recto-sigmoid mucosa, like at the disease onset, and when we reached the cecum an erythematous area circumscribed to the appendiceal orifice was observed, with a mucosal aspect identical to the described for the recto-sigmoid mucosa. The biopsies taken from that area were compatible with ulcerative colitis. We herein describe the details of the case and review the literature.

5. On the Existence of Subharmonic Screech in Choked Circular Jets from a Sharp-Edged Orifice

NASA Technical Reports Server (NTRS)

Kandula, Max

2014-01-01

Experiments are performed in choked circular hot and cold nitrogen jets issuing from a 2.44 cm diameter sharp-edged orifice at a fully expanded jet Mach number of 1.85 in an effort to investigate the character of screech phenomenon. The stagnation temperature of the cold and the hot jets are 299 K and 319 K respectively. The axial distribution of the centerline Mach number was obtained with a pitot tube, while the screech data (frequency and amplitude) at different axial and radial stations were measured with the aid of microphones. The fundamental screech frequency of the hot jet is slightly increased relative to that of the cold jet. It is concluded that temperature effects on the screech amplitude are manifested with regard to the fundamental and the subharmonic even at relatively small temperature range considered.

6. Current developments in natural orifices transluminal endoscopic surgery: An evidence-based review

PubMed Central

Teoh, Anthony Yuen Bun; Chiu, Philip Wai Yan; Ng, Enders Kwok Wai

2010-01-01

Tremendous advances have been made in recent years addressing the key obstacles to safe performance and introduction of human natural orifice transluminal endoscopic surgery (NOTES). Animal studies have focused on identifying optimal solutions to these obstacles, in particular methods of creating transluminal access, safe closure of the point of access, and development of a multitasking platform with dedicated instruments. Whether the performance data generated from these animal studies can be reproduced in humans has yet to be determined. Reports of human NOTES procedures are emerging, and the possibility of accomplishing human NOTES based on existing technology has been demonstrated. However, dedicated platforms and devices are still lacking to allow for pure NOTES procedures, and whether NOTES can deliver the postulated benefits of earlier recovery and improved cosmesis remains uncertain. PMID:20939107

7. Rationale and feasibility of intranasal delivery of drugs to the eustachian tube orifice.

PubMed

Rashid, Mamun

2012-12-01

Intranasal medication for eustachian tube dysfunction (ETD) is an established practice in otolaryngology through the effects of steroids, decongestants, antihistamines or a combination of the above in reducing tubal oedema. The author has previously argued that a double-blind, randomised control trial would be helpful in determining effectiveness of treatment, if a standardised head position, chiefly Mygind or Ragan, was adopted to maximise intranasal drop delivery into the eustachian tube orifice. One recent paper suggests that intranasal treatment is not very effective, but ultimately does not state whether a standardised head position was adopted. Although a large body of evidence supports the hypothesis that the nasal passages are the route to middle ear disease, there is as yet no paper that has been published that has specifically addressed this issue, therefore the author must conclude that evidence to support intranasal treatment for ETD is still lacking and further research is desirable.

8. [Natural orifice trans-luminal endoscopic surgery (notes)--a new era in general surgery].

PubMed

Elazary, Ram; Horgan, Santiago; Talamini, Mark A; Rivkind, Avraham I; Mintz, Yoav

2008-10-01

Four years ago, a new surgical technique was presented, the natural orifice trans-luminal endoscopic surgery (NOTES). This technique provides an incisionless operation. The surgical devices are inserted into the peritoneal cavity through the gastrointestinal or the urogenital tracts. Today, a cholecystectomy can be performed using an advanced endoscope inserted through the stomach or the vagina. The advantages of NOTES are: reduced post operative pain, no hernias, no surgical wounds infections and better cosmetic results. The disadvantages are: difficulties in achieving safe enterotomy closure or a leak proof anastomosis, it necessitates performing more operations compared to open or laparoscopic operations in order to obtain the skills for performing these operations, and difficulties of acquiring satisfactory endoscopic vision due to lack of advanced technology. Several NOTES operations have already been performed in humans. However, many other surgical procedures were tested in laboratory animals. Development and improvement of surgical devices may promote this surgical modality in the future.

9. Manufacturer-provided effective orifice area index charts and the prevention of prosthesis-patient mismatch.

PubMed

House, Chad M; Nelson, William B; Kroshus, Timothy J; Dahiya, Ranjan; Pibarot, Philippe

2012-01-01

Prosthesis-patient mismatch (PPM) occurs when an implanted prosthesis is too small relative to the patient's body surface area (BSA). However, mismatch can often be prevented by indexing the expected effective orifice area (EOA) of a prosthesis to the patient's BSA and then selecting the largest implantable prosthesis to avoid mismatch. Previously, prosthesis manufacturers have attempted to simplify this process by providing charts that include the expected EOA for their prosthesis, already indexed into an array of BSA values. One caveat with these charts is that the expected EOA data must truly be reliable, or the charts will misguide the implanting surgeon. Manufacturer-provided charts could be improved by standardizing the EOA data, with one potential source being the hemodynamic data submitted to the United States Food and Drug Administration. This review discusses PPM, manufacturer-provided EOA charts, and the regulation of EOA data.

10. Continuous focusing of microparticles using inertial lift force and vorticity via multi-orifice microfluidic channels.

PubMed

Park, Jae-Sung; Song, Suk-Heung; Jung, Hyo-Il

2009-04-07

We developed a new microfluidic method for focusing microparticles through the combined use of inertial lift forces and turbulent secondary flows generated in a topographically patterned microchannel. The mechanism of particle focusing is based on the hydrodynamic inertial forces exerted on particles migrating along a non-circular microchannel, i.e.tubular pinch effect and wall effect, which induce particle movement away from walls and along a specific lateral position in the microchannel. With the extraordinary geometry of multi-orifice microchannel, an ordered and focused particle distribution was achieved at central or side regions according to a particle Reynolds number (Re(p)) range. The focusing of particles was controlled by the particle Reynolds number, microchannel length, and volume fraction of particles in suspension. This method will be beneficial in particle focusing processes in a microfluidic device since it offers continuous, high-throughput performance and simple operation.

11. Climatology of Station Storm Rainfall in the Continental United States: Parameters of the Bartlett-Lewis and Poisson Rectangular Pulses Models

NASA Technical Reports Server (NTRS)

Hawk, Kelly Lynn; Eagleson, Peter S.

1992-01-01

The parameters of two stochastic models of point rainfall, the Bartlett-Lewis model and the Poisson rectangular pulses model, are estimated for each month of the year from the historical records of hourly precipitation at more than seventy first-order stations in the continental United States. The parameters are presented both in tabular form and as isopleths on maps. The Poisson rectangular pulses parameters are useful in implementing models of the land surface water balance. The Bartlett-Lewis parameters are useful in disaggregating precipitation to a time period shorter than that of existing observations. Information is also included on a floppy disk.

12. Modeling and High-Throughput Experimental Data Uncover the Mechanisms Underlying Fshb Gene Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency.

PubMed

Stern, Estee; Ruf-Zamojski, Frederique; Zalepa-King, Lisa; Pincas, Hanna; Choi, Soon Gang; Peskin, Charles S; Fernand, Hayot; Turgeon, Judith L; Sealfon, Stuart C

2017-04-06

Neuroendocrine control of reproduction by brain-secreted pulses of gonadotropin-releasing hormone (GnRH) represents a longstanding puzzle about extracellular signal decoding mechanisms. GnRH regulates the pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH), both of which are heterodimers specified by unique β subunits (FSHβ/LHβ). Contrary to Lhb, Fshb gene induction has a preference for low frequency GnRH pulses. To clarify the underlying regulatory mechanisms, we developed three biologically anchored mathematical models: 1) parallel activation of Fshb inhibitory factors (e.g. inhibin α and VGF nerve growth factor-inducible), 2) activation of a signaling component with a refractory period (e.g. G protein), and 3) inactivation of a factor needed for Fshb induction (e.g. growth differentiation factor 9). Simulations with all three models recapitulated the Fshb expression levels obtained in pituitary gonadotrope cells perifused with varying GnRH pulse frequencies. Notably, simulations altering average concentration, pulse duration, and pulse frequency revealed that the apparent frequency-dependent pattern of Fshb expression in model 1 actually resulted from variations in average GnRH concentration. In contrast, models 2 and 3 showed »true» pulse frequency sensing. To resolve which components of this GnRH signal induce Fshb, we developed a high-throughput parallel experimental system. We analyzed over 4,000 samples in experiments with varying near-physiological GnRH concentrations and pulse patterns. While Egr1 and Fos genes responded only to variations in average GnRH concentration, Fshb levels were sensitive to both average concentration and true pulse frequency. These results provide a foundation for understanding the role of multiple regulatory factors in modulating Fshb gene activity.

13. Time-resolved non-sequential ray-tracing modelling of non-line-of-sight picosecond pulse LIDAR

Sroka, Adam; Chan, Susan; Warburton, Ryan; Gariepy, Genevieve; Henderson, Robert; Leach, Jonathan; Faccio, Daniele; Lee, Stephen T.

2016-05-01

The ability to detect motion and to track a moving object that is hidden around a corner or behind a wall provides a crucial advantage when physically going around the obstacle is impossible or dangerous. One recently demonstrated approach to achieving this goal makes use of non-line-of-sight picosecond pulse laser ranging. This approach has recently become interesting due to the availability of single-photon avalanche diode (SPAD) receivers with picosecond time resolution. We present a time-resolved non-sequential ray-tracing model and its application to indirect line-of-sight detection of moving targets. The model makes use of the Zemax optical design programme's capabilities in stray light analysis where it traces large numbers of rays through multiple random scattering events in a 3D non-sequential environment. Our model then reconstructs the generated multi-segment ray paths and adds temporal analysis. Validation of this model against experimental results is shown. We then exercise the model to explore the limits placed on system design by available laser sources and detectors. In particular we detail the requirements on the laser's pulse energy, duration and repetition rate, and on the receiver's temporal response and sensitivity. These are discussed in terms of the resulting implications for achievable range, resolution and measurement time while retaining eye-safety with this technique. Finally, the model is used to examine potential extensions to the experimental system that may allow for increased localisation of the position of the detected moving object, such as the inclusion of multiple detectors and/or multiple emitters.

14. Multiple-orifice liquid injection into hypersonic airstreams and applications to ram C-3 flight

NASA Technical Reports Server (NTRS)

Weaver, W. L.

1972-01-01

Experimental data are presented for the oblique injection of water and three electrophilic liquids (fluorocarbon compounds) through multiple-orifice nozzles from a flat plate and the sides of a hemisphere-cone (0.375 scale of RAM C spacecraft) into hypersonic airstreams. The nozzle patterns included single and multiple orifices, single rows of nozzles, and duplicates of the RAM C-III nozzles. The flat-plate tests were made at Mach 8. Total pressure was varied from 3.45 MN/m2 to 10.34 MN/m2, Reynolds number was varied form 9,840,000 per meter to 19,700,000 per meter, and liquid injection pressure was varied from 0.69 MN/m2 to 3.5 MN/m2. The hemisphere-cone tests were made at Mach 7.3. Total pressure was varied from 1.38 MN/m2, to 6.89 MN/m2, Reynolds number was varied from 3,540,000 per meter to 17,700,000 per meter, and liquid-injection pressure was varied from 0.34 MN/m2 to 4.14 MN/m2. Photographs of the tests and plots of liquid-penetration and spray cross-section area are presented. Maximum penetration was found to vary as the square root of the dynamic-pressure ratio and the square root of the total injection nozzle area. Spray cross-section area was linear with maximum penetration. The test results are used to compute injection parameters for the RAM C-3 flight injection experiment.

15. Sequential kinetic modelling: A new tool decodes pulsed tectonic patterns in early hot orogens of Earth

Bhowmik, Santanu Kumar; Chakraborty, Sumit

2017-02-01

Tectonic styles in an early hot Earth were different from the present-day situation governed by plate tectonics. Processes in such hot settings remain poorly understood because they often occur on timescales that are below the resolution of conventional isotopic clocks, the rock records are fragmentary, and these have been superposed by later high-temperature events. We have developed a tool based on diffusion kinetics to overcome these difficulties and reconstruct sequences of short-lived episodes. Application of the method to a rock from the ultra-hot c.1.6 Ga orogenic domain of the Central Indian Tectonic Zone, where additional data are available to verify the results, shows that pulses of approach and roll-back of colliding plates preceded the final closure and collision. We demonstrate that cooling from ultra-high temperature metamorphic conditions in the orogen took place in multiple pulses that occurred with a periodicity of about 10 Myr at rates that vary between 100's to 10's °C/Myr, and burial-/exhumation-rates that vary between 30 and 2 km/Myr, respectively. Such details of tectonic processes in the Precambrian, with quantification of variable heating-, cooling-, burial-, and exhumation-rates of individual stages, have not been accessible until now. Application of this method to other regions would provide a means of exploring the thermal viability of the inferred long durations (>100 Myr) for some ultra-high temperature orogenies.

16. Modeling of three-dimensional Lamb wave propagation excited by laser pulses.

PubMed

Liu, Wenyang; Hong, Jung-Wuk

2015-01-01

As a type of broadband source of ultrasonic guided waves, laser pulses can be used to launch all modes of interests. In this paper, Lamb waves are excited by imposing heat flux mimicking the supply of the heat from laser pulses, and effects by defects on the received Lamb waves in a plate are investigated by means of the finite element method. In order to alleviate the heavy computational cost in solving the coupled finite element equations, a sub-regioning scheme is employed, and it reduces the computational cost significantly. A comparison of Lamb waves generated by unfocused and line-focused laser sources is conducted. To validate numerical simulations, the group velocity of A0 mode is calculated based on the received signal by using the wavelet transform. The result of A0 mode group velocity is compared with the solution of Rayleigh-Lamb equations, and close agreement is observed. Lamb waves in a plate with defects of different lengths are examined next. The out-of-plane displacement in the plate with a defect is compared with the displacement in the plate without defects, and the wavelet transform is used to determine the arrival times of Lamb waves traveling at the A0 mode group velocity. A strong correlation is observed between the extent of defects and the magnitude of wavelet coefficients.

17. Variability in time delay between two models of pulse oximeters for deriving the photoplethysmographic signals.

PubMed

Foo, Jong Yong A; Wilson, Stephen J; Dakin, Carolyn; Williams, Gordon; Harris, Margaret-Anne; Cooper, David

2005-08-01

Pulse oximetry is commonly used as an arterial blood oxygen saturation (SaO2) measure. However, its other serial output, the photoplethysmography (PPG) signal, is not as well studied. Raw PPG signals can be used to estimate cardiovascular measures like pulse transit time (PTT) and possibly heart rate (HR). These timing-related measurements are heavily dependent on the minimal variability in phase delay of the PPG signals. Masimo SET Rad-9 and Novametrix Oxypleth oximeters were investigated for their PPG phase characteristics on nine healthy adults. To facilitate comparison, PPG signals were acquired from fingers on the same hand in a random fashion. Results showed that mean PTT variations acquired from the Masimo oximeter (37.89 ms) were much greater than the Novametrix (5.66 ms). Documented evidence suggests that 1 ms variation in PTT is equivalent to 1 mmHg change in blood pressure. Moreover, the PTT trend derived from the Masimo oximeter can be mistaken as obstructive sleep apnoeas based on the known criteria. HR comparison was evaluated against estimates attained from an electrocardiogram (ECG). Novametrix differed from ECG by 0.71+/-0.58% (p<0.05) while Masimo differed by 4.51+/-3.66% (p>0.05). Modern oximeters can be attractive for their improved SaO2 measurement. However, using raw PPG signals obtained directly from these oximeters for timing-related measurements warrants further investigations.

18. Building A Simulation Model For The Prediction Of Temperature Distribution In Pulsed Laser Spot Welding Of Dissimilar Low Carbon Steel 1020 To Aluminum Alloy 6061

SciTech Connect

2011-01-17

This paper describes the development of a computer model used to analyze the heat flow during pulsed Nd: YAG laser spot welding of dissimilar metal; low carbon steel (1020) to aluminum alloy (6061). The model is built using ANSYS FLUENT 3.6 software where almost all the environments simulated to be similar to the experimental environments. A simulation analysis was implemented based on conduction heat transfer out of the key hole where no melting occurs. The effect of laser power and pulse duration was studied.Three peak powers 1, 1.66 and 2.5 kW were varied during pulsed laser spot welding (keeping the energy constant), also the effect of two pulse durations 4 and 8 ms (with constant peak power), on the transient temperature distribution and weld pool dimension were predicated using the present simulation. It was found that the present simulation model can give an indication for choosing the suitable laser parameters (i.e. pulse durations, peak power and interaction time required) during pulsed laser spot welding of dissimilar metals.

19. In vitro and in vivo evaluation of a novel push-pull osmotic pump with orifices on both side surfaces.

PubMed

Li, Wei; Du, Gani; Yang, Xinggang; Zhang, Zhihong; Nie, Shufang; Peng, Bo; Pan, Weisan

2008-12-01

A novel push-pull osmotic pump (PPOP) was developed for delivery of water-insoluble drug gliclazide. Compared to conventional PPOP, which only had orifice(s) on the side of the drug layer, the novel PPOP had orifices of the same diameter on both side surfaces. The in vitro drug-release behavior of both novel PPOP and conventional PPOP were studied and compared; it was found that the drug-release rate of both kinds of PPOP could be influenced by coating level and core hardness whereas orifice size did not have much influence on it, and the study also showed that none of the former factors could influence the similarity of the drug-release profiles of the two kinds of PPOP. Mechanism of drug release from novel PPOP was illustrated using Poiseuille's law of lamina flow, and it was found that under regular formulation, the dissolution profiles of the two kinds of PPOP were similar. In vivo study also showed that the concentration-time profiles of gliclazide in plasma of the two PPOP were comparable and both of them had good in vitro-in vivo correlation. By simply drilled on both side surfaces, the novel PPOP did not need side identification when drilled, so it was more suitable for industrial manufacture than the conventional ones.

20. Modeling the Effects of Beam Size and Flaw Morphology on Ultrasonic Pulse/Echo Sizing of Delaminations in Carbon Composites

NASA Technical Reports Server (NTRS)

Margetan, Frank J.; Leckey, Cara A.; Barnard, Dan

2012-01-01

The size and shape of a delamination in a multi-layered structure can be estimated in various ways from an ultrasonic pulse/echo image. For example the -6dB contours of measured response provide one simple estimate of the boundary. More sophisticated approaches can be imagined where one adjusts the proposed boundary to bring measured and predicted UT images into optimal agreement. Such approaches require suitable models of the inspection process. In this paper we explore issues pertaining to model-based size estimation for delaminations in carbon fiber reinforced laminates. In particular we consider the influence on sizing when the delamination is non-planar or partially transmitting in certain regions. Two models for predicting broadband sonic time-domain responses are considered: (1) a fast "simple" model using paraxial beam expansions and Kirchhoff and phase-screen approximations; and (2) the more exact (but computationally intensive) 3D elastodynamic finite integration technique (EFIT). Model-to-model and model-to experiment comparisons are made for delaminations in uniaxial composite plates, and the simple model is then used to critique the -6dB rule for delamination sizing.