Physico-chemical behaviour of β irradiated plastic materials currently used as packagings and medical products

NASA Astrophysics Data System (ADS)

Yagoubi, N.; Baillet, A.; Pellerin, F.; Ferrier, D.

1995-11-01

The combined chromatographic technics and thermal analysis constitute an informative methodology for studying the modifications which could occur following a radiotreatment of plastic material at different doses (25 to 100 kGy). Several plastic materials used as packagings (PVC, PE, PS) were investigated. SEC method coupled with UV and DDL detections was applied to document any changes in molecular weight distribution. Reticulation and scission were the main observed degradation phenomena. These structural modifications were supported by TGA data, while the DSC provided information on modifications in crystallinity. In addition, RP-HPLC was carried out for the evaluation of the radiochemical behaviour of the additives and monomers. Firstly we demonstrated the degradation of high molecular weight phenolic antioxidants in BHT within the PEVA. Secondly, the modifications of amino 6 caproic acid and ɛ caprolactam, present in polyamid 6, depend on the irradiation doses.

Constitutional Provisions on the Press: A World View.

ERIC Educational Resources Information Center

Paraschos, Manny

A study examined the legal treatment of the press in constitutions or other basic legal institutional documents from around the world. Sixty-three constitutions or basic documents from the Western World, the Communist Bloc, the Middle East, Africa, Southeast Asia, and Latin America were analyzed. Analysis revealed that most constitutions open with…

40 CFR 725.60 - Withdrawal of submission by the submitter.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., OPPT Document Control Office (DCO), EPA East Bldg., 1201 Constitution Ave., NW., Rm. 6428, Washington... Control Office (DCO), EPA East Bldg., 1201 Constitution Ave., NW., Rm. 6428, Washington, DC 20004. (ii... Document Control Office (DCO), EPA East Bldg., 1201 Constitution Ave., NW., Rm. 6428, Washington, DC 20004...

Addendum to the Closure Report for Corrective Action Unit 326: Areas 6 and 27 Release Sites, Nevada Test Site, Nevada, Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant Evenson

This document constitutes an addendum to the Closure Report for Corrective Action Unit 326: Areas 6 and 27 Release Sites, Nevada Test Site, Nevada (Revision 1), December 2002 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additional information • Themore » cover, title, and signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the UR for CAS 06-25-01, CP-1 Heating Oil Release. This UR was established as part of a Federal Facility Agreement and Consent Order (FFACO) corrective action and is based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since this UR was established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, this UR was reevaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the UR) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove the UR because contamination is not present at the site above the risk-based FALs. Requirements for inspecting and maintaining this UR will be canceled, and the postings and signage at this site will be removed. Fencing and posting may be present at this site that are unrelated to the FFACO UR such as for radiological control purposes as required by the NV/YMP Radiological Control Manual (NNSA/NSO, 2004). This modification will not affect or modify any non-FFACO requirements for fencing, posting, or monitoring at this site.« less

Addendum to the Closure Report for Corrective Action Unit 403: Second Gas Station, Tonopah Test Range, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant Evenson

This document constitutes an addendum to the Closure Report for Corrective Action Unit 403: Second Gas Station, Tonopah Test Range, Nevada, September 1998 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additional information • The cover, title, and signature pagesmore » of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the UR for CAS 03-02-004-0360, Underground Storage Tanks. This UR was established as part of a Federal Facility Agreement and Consent Order (FFACO) corrective action and is based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since this UR was established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, this UR was reevaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the UR) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove the UR because contamination is not present at the site above the risk-based FALs. Requirements for inspecting and maintaining this UR will be canceled, and the postings and signage at this site will be removed. Fencing and posting may be present at this site that are unrelated to the FFACO UR such as for radiological control purposes as required by the NV/YMP Radiological Control Manual (NNSA/NSO, 2004). This modification will not affect or modify any non-FFACO requirements for fencing, posting, or monitoring at this site.« less

Addendum to the Closure Report for Corrective Action Unit 339: Area 12 Fleet Operations Steam Cleaning Discharge Area, Nevada Test Site, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant Evenson

This document constitutes an addendum to the Closure Report for CAU 339: Area 12 Fleet Operations Steam Cleaning Discharge Area Nevada Test Site, December 1997 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additional information • The cover, title, andmore » signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the UR for CAS 12-19-01, A12 Fleet Ops Steam Cleaning Efflu. This UR was established as part of a Federal Facility Agreement and Consent Order (FFACO) corrective action and is based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since this UR was established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, this UR was reevaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the UR) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove the UR because contamination is not present at the site above the risk-based FALs. Requirements for inspecting and maintaining this UR will be canceled, and the postings and signage at this site will be removed. Fencing and posting may be present at this site that are unrelated to the FFACO UR such as for radiological control purposes as required by the NV/YMP Radiological Control Manual (NNSA/NSO, 2004). This modification will not affect or modify any non-FFACO requirements for fencing, posting, or monitoring at this site.« less

Addendum 2 to the Closure Report for Corrective Action Unit 358: Areas 18, 19, 20 Cellars/Mud Pits, Nevada Test Site, Nevada, Revison 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant Evenson

This document constitutes an addendum to the Closure Report for Corrective Action Unit 358: Areas 18, 19, 20 Cellars/Mud Pits, Nevada Test Site, Nevada, January 2004 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additional information • The cover, title,more » and signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the UR for CAS 19-09-05, Mud Pit. This UR was established as part of a Federal Facility Agreement and Consent Order (FFACO) corrective action and is based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since this UR was established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, this UR was reevaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the UR) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove the UR because contamination is not present at the site above the risk-based FALs. Requirements for inspecting and maintaining this UR will be canceled, and the postings and signage at this site will be removed. Fencing and posting may be present at this site that are unrelated to the FFACO UR such as for radiological control purposes as required by the NV/YMP Radiological Control Manual (NNSA/NSO, 2004). This modification will not affect or modify any non-FFACO requirements for fencing, posting, or monitoring at this site.« less

From Confederation to Constitution: 1781-1789.

ERIC Educational Resources Information Center

Urofsky, Melvin I.; Cox, Nancy

Students should achieve a higher level of understanding and appreciation of the evolving nature of the U.S. Constitution and its relevance to contemporary societal issues by studying historical documents from the period of time between the Articles of Confederation and the Constitution. This document begins with a history of that period and of the…

Public Hearing and Comment Period Documents for the Northeast Gateway Energy Bridge Deepwater, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

EPA Pesticide Factsheets

List of public hearing & comment period document(s) for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

75 FR 7616 - Mitigation of Carrier Fines for Transporting Aliens Without Proper Documents; Modification of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-22

... Transporting Aliens Without Proper Documents; Modification of Memorandum of Understanding and Recalculation of... States an alien who does not have a valid passport and an unexpired visa, as required under applicable law, is subject to a fine for each alien transported lacking the required documentation. Pursuant to...

8 CFR 1244.18 - Issuance of charging documents; detention.

Code of Federal Regulations, 2010 CFR

2010-01-01

... seek such a waiver in deportation or exclusion proceedings. The charging document shall constitute... JUSTICE IMMIGRATION REGULATIONS TEMPORARY PROTECTED STATUS FOR NATIONALS OF DESIGNATED STATES § 1244.18... of deportation or exclusion against an alien granted Temporary Protected Status shall constitute a...

Addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 452: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant Evenson

This document constitutes an addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 452: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, April 1998 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additionalmore » information • The cover, title, and signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the URs for CASs: • 25-25-09, Spill H940825C (from UST 25-3101-1) • 25-25-14, Spill H940314E (from UST 25-3102-3) • 25-25-15, Spill H941020E (from UST 25-3152-1) These URs were established as part of Federal Facility Agreement and Consent Order (FFACO) corrective actions and were based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since these URs were established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, these URs were re-evaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the URs) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove these URs because contamination is not present at these sites above the risk-based FALs. Requirements for inspecting and maintaining these URs will be canceled, and the postings and signage at each site will be removed. Fencing and posting may be present at these sites that are unrelated to the FFACO URs such as for radiological control purposes as required by the NV/YMP Radiological Control Manual (NNSA/NSO, 2004). This modification will not affect or modify any non-FFACO requirements for fencing, posting, or monitoring at these sites.« less

Addendum 2 to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grant Evenson

This document constitutes an addendum to the Streamlined Approach for Environmental Restoration Closure Report for Corrective Action Unit 454: Historical Underground Storage Tank Release Sites, Nevada Test Site, Nevada, April 1998 as described in the document Supplemental Investigation Report for FFACO Use Restrictions, Nevada Test Site, Nevada (SIR) dated November 2008. The SIR document was approved by NDEP on December 5, 2008. The approval of the SIR document constituted approval of each of the recommended UR removals. In conformance with the SIR document, this addendum consists of: • This page that refers the reader to the SIR document for additionalmore » information • The cover, title, and signature pages of the SIR document • The NDEP approval letter • The corresponding section of the SIR document This addendum provides the documentation justifying the cancellation of the URs for CASs: • 12-25-08, Spill H950524F (from UST 12-B-1) • 12-25-10, Spill H950919A (from UST 12-COMM-1) These URs were established as part of Federal Facility Agreement and Consent Order (FFACO) corrective actions and were based on the presence of contaminants at concentrations greater than the action levels established at the time of the initial investigation (FFACO, 1996). Since these URs were established, practices and procedures relating to the implementation of risk-based corrective actions (RBCA) have changed. Therefore, these URs were re-evaluated against the current RBCA criteria as defined in the Industrial Sites Project Establishment of Final Action Levels (NNSA/NSO, 2006). This re-evaluation consisted of comparing the original data (used to define the need for the URs) to risk-based final action levels (FALs) developed using the current Industrial Sites RBCA process. The re-evaluation resulted in a recommendation to remove these URs because contamination is not present at these sites above the risk-based FALs. Requirements for inspecting and maintaining these URs will be canceled, and the postings and signage at each site will be removed. Fencing and posting may be present at these sites that are unrelated to the FFACO URs such as for radiological control purposes as required by the NV/YMP Radiological Control Manual (NNSA/NSO, 2004). This modification will not affect or modify any non-FFACO requirements for fencing, posting, or monitoring at these sites.« less

Association Between the Occurrence of Adverse Drug Events and Modification of First-Line Highly Active Antiretroviral Therapy in Ghanaian HIV Patients.

PubMed

Tetteh, Raymond A; Nartey, Edmund T; Lartey, Margaret; Mantel-Teeuwisse, Aukje K; Leufkens, Hubert G M; Yankey, Barbara A; Dodoo, Alexander N O

2016-11-01

Patients initiated on highly active antiretroviral therapy (HAART) generally remain on medication indefinitely. A modification in the HAART regimen may become necessary because of possible acute or chronic toxicities, concomitant clinical conditions, development of virological failure or the advent of adverse drug events. The study documents adverse drug events of HIV-positive Ghanaian patients with HAART modifications. It also investigates the association between documented adverse drug events and HAART modification using an unmatched case-control study design. The study was conducted in the Fevers Unit of the Korle Bu Teaching Hospital and involved patients who attended the HIV Care Clinic between January 2004 and December 2009. Data from 298 modified therapy patients (cases) were compared with 298 continuing therapy patients (controls) who had been on treatment for at least 1 month before the end of study. Controls were sampled from the same database of a cohort of HIV-positive patients on HAART, at the time a case occurred, in terms of treatment initiation ±1 month. Data were obtained from patients' clinical folders and the HIV clinic database linked to the pharmacy database. The nature of the documented adverse drug events of the cases was described and the association between the documented adverse drug events and HAART modification was determined by logistic regression with reported odds ratios (ORs) and their 95 % confidence interval (CI). Among the 298 modified therapy patients sampled in this study, 52.7 % of them had at least one documented adverse drug event. The most documented adverse drug event was anaemia, recorded in 18.5 % of modified therapy patients, all of whom were on a zidovudine-based regimen. The presence of documented adverse drug events was significantly associated with HAART modification [adjusted OR = 2.71 (95 % CI 2.11-3.48), p < 0.001]. Among HIV patients on HAART, adverse drug events play a major role in treatment modification. Occurrence of adverse drug events may be used as a predictor for possible therapy modification. We recommend the institution of active pharmacovigilance in HIV treatment programmes as it permits the proper identification and characterisation of drug-related adverse events. This can help develop approaches towards their management and also justify therapy modifications.

Educators' Handbook on Federal Anti-Sex Discrimination Laws.

ERIC Educational Resources Information Center

Mercer, James

The document presents a summary of major federal legislation affecting the policy and operation of educational programs and activities. The handbook is intended to help educators locate information on the constitutional aspects of anti-discrimination laws. The document is presented in four chapters. Chapter I discusses the constitutional aspects…

45 CFR 641.19 - Modification of environmental documents.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 3 2013-10-01 2013-10-01 false Modification of environmental documents. 641.19 Section 641.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION ENVIRONMENTAL ASSESSMENT PROCEDURES FOR PROPOSED NATIONAL SCIENCE FOUNDATION ACTIONS IN ANTARCTICA...

45 CFR 641.19 - Modification of environmental documents.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 3 2012-10-01 2012-10-01 false Modification of environmental documents. 641.19 Section 641.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION ENVIRONMENTAL ASSESSMENT PROCEDURES FOR PROPOSED NATIONAL SCIENCE FOUNDATION ACTIONS IN ANTARCTICA...

45 CFR 641.19 - Modification of environmental documents.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Modification of environmental documents. 641.19 Section 641.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION ENVIRONMENTAL ASSESSMENT PROCEDURES FOR PROPOSED NATIONAL SCIENCE FOUNDATION ACTIONS IN ANTARCTICA...

45 CFR 641.19 - Modification of environmental documents.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 3 2011-10-01 2011-10-01 false Modification of environmental documents. 641.19 Section 641.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION ENVIRONMENTAL ASSESSMENT PROCEDURES FOR PROPOSED NATIONAL SCIENCE FOUNDATION ACTIONS IN ANTARCTICA...

45 CFR 641.19 - Modification of environmental documents.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 3 2014-10-01 2014-10-01 false Modification of environmental documents. 641.19 Section 641.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION ENVIRONMENTAL ASSESSMENT PROCEDURES FOR PROPOSED NATIONAL SCIENCE FOUNDATION ACTIONS IN ANTARCTICA...

Power: Constitutional Update. Bar/School Partnership Programs Series.

ERIC Educational Resources Information Center

American Bar Association, Chicago, IL. Special Committee on Youth Education for Citizenship.

The fourth in a special series of handbooks dealing with constitutional themes, this document looks at power in the context of the U.S. Constitution. "The Constitution's Prescription for Freedom" (L. Peach) examines the separation of powers provided for in the Constitution. "The Concept of Power" (C. Roach) is a series of…

Draft Permit & Supporting Documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project)

EPA Pesticide Factsheets

List of draft permit & supporting documentation for the Northeast Gateway Energy Bridge Deepwater Port, Federal Waters of Massachusetts Bay (Modification to Existing Permit LNG Regasification Vessel/DWP Project).

a 3d GIS Method Applied to Cataloging and Restoring: the Case of Aurelian Walls at Rome

NASA Astrophysics Data System (ADS)

Canciani, M.; Ceniccola, V.; Messi, M.; Saccone, M.; Zampilli, M.

2013-07-01

The project involves architecture, archaeology, restoration, graphic documentation and computer imaging. The objective is development of a method for documentation of an architectural feature, based on a three-dimensional model obtained through laser scanning technologies, linked to a database developed in GIS environment. The case study concerns a short section of Rome's Aurelian walls, including the Porta Latina. The city walls are Rome's largest single architectural monument, subject to continuous deterioration, modification and maintenance since their original construction beginning in 271 AD. The documentation system provides a flexible, precise and easily-applied instrument for recording the full appearance, materials, stratification palimpsest and conservation status, in order to identify restoration criteria and intervention priorities, and to monitor and control the use and conservation of the walls over time. The project began with an analysis and documentation campaign integrating direct, traditional recording methods with indirect, topographic instrument and 3D laser scanning recording. These recording systems permitted development of a geographic information system based on three-dimensional modelling of separate, individual elements, linked to a database and related to the various stratigraphic horizons, the construction techniques, the component materials and their state of degradation. The investigations of the extant wall fabric were further compared to historic documentation, from both graphic and descriptive sources. The resulting model constitutes the core of the GIS system for this specific monument. The methodology is notable for its low cost, precision, practicality and thoroughness, and can be applied to the entire Aurelian wall and to other monuments.

77 FR 27669 - Modifications to Definition of United States Property

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

... Modifications to Definition of United States Property AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... contracts. The temporary regulations provide that certain obligations of United States persons arising from... derivatives clearing organization or clearing agency do not constitute United States property. The text of the...

75 FR 51433 - Modifications of Debt Instruments; Hearing Cancellation

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

... DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 [REG-106750-10] RIN 1545-BJ30 Modifications of Debt Instruments; Hearing Cancellation AGENCY: Internal Revenue Service (IRS), Treasury. ACTION... auditorium, Internal Revenue Building, 1111 Constitution Avenue, NW., Washington, DC. The subject of the...

39 CFR 3020.91 - Modification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Change the Mail Classification Schedule § 3020.91 Modification. The Postal Service shall submit corrections to product descriptions in the Mail Classification Schedule that do not constitute a proposal to modify the market dominant product list or the competitive product list as defined in § 3020.30 by filing...

39 CFR 3020.91 - Modification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Change the Mail Classification Schedule § 3020.91 Modification. The Postal Service shall submit corrections to product descriptions in the Mail Classification Schedule that do not constitute a proposal to modify the market dominant product list or the competitive product list as defined in § 3020.30 by filing...

Reflections on the Establishment of Constitutional Government in Eastern Europe.

ERIC Educational Resources Information Center

Varat, Jonathan D.

Establishing constitutional government involves not simply the creation of a written document that purports to create the political structure of a nation and guarantee rights to its people, but "constitutionalism" in the sense of meaningful and effective adherence to constitutional norms of democratic organization and the protection of…

James Madison's "Public" As Interpreter of the Constitution.

ERIC Educational Resources Information Center

Dewey, Donald O.

James Madison's thoughts on various interpretations of the Constitution maintain that public opinion is the ultimate method of legitimizing the document. The Constitution must prevail against mere public opinion, but public opinion may be used to establish the meaning of the Constitution when conflicting interpretations exist. The public good and…

Becoming Informed Citizens: Lessons on the Constitution for Junior High School Students.

ERIC Educational Resources Information Center

Wagner, Kenneth A.; And Others

This document consists of lesson plans for teaching junior high school students about the U.S. Constitution. Lessons are derived from teaching methods that instructors have found useful and appropriate for the actual condition of the ordinary classroom, and account for the characteristics and needs of the early adolescent. The document includes a…

Nacao e Cidadania: A Constituicao de 1824 e Suas Implicacoes Politicas (Nation and Citizenship: The Constitution of 1824 and Its Political Implications).

ERIC Educational Resources Information Center

Oliveira, Cecilia Helena Lorenzini de Salles

1998-01-01

Brings a different reading of 1824's Brazilian Imperial Political Constitution. Discusses some historical and political circumstances of the document's construction. Investigates practices, conceptions, and supports that could have clarified some principles stressed by the document, especially those related to citizenship matters. (PA)

Constitutional Debates on Freedom of Religion: A Documentary History. Primary Documents in American History and Contemporary Issues.

ERIC Educational Resources Information Center

Patrick, John J., Ed.; Long, Gerald P., Ed.

Debates over the separation or accommodation of religion and government have divided the United States since its founding. This collection of over 70 primary documents represents the ideas and issues on the interpretation of the United States Constitution's First Amendment clauses pertaining to establishment and free exercise of religion. The…

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

48 CFR 801.602-83 - Documents to submit for legal or technical review-contract modifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Documents to submit for legal or technical review-contract modifications. 801.602-83 Section 801.602-83 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION...

Studying radiolytic ageing of nuclear power plant electric cables with FTIR spectroscopy.

PubMed

Levet, A; Colombani, J; Duponchel, L

2017-09-01

Due to the willingness to extend the nuclear power plants length of life, it is of prime importance to understand long term ageing effect on all constitutive materials. For this purpose gamma-irradiation effects on insulation of instrumentation and control cables are studied. Mid-infrared spectroscopy and principal components analysis (PCA) were used to highlight molecular modifications induced by gamma-irradiation under oxidizing conditions. In order to be closer to real world conditions, a low dose rate of 11Gyh -1 was used to irradiate insulations in full cable or alone with a dose up to 58 kGy. Spectral differences according to irradiation dose were extracted using PCA. It was then possible to observe different behaviors of the insulation constitutive compounds i.e. ethylene vinyl acetate (EVA), ethylene propylene diene monomer (EPDM) and aluminium trihydrate (ATH). Irradiation of insulations led to the oxidation of their constitutive polymers and a modification of filler-polymer ratio. Moreover all these modifications were observed for insulations alone or in full cable indicating that oxygen easily diffuses into the material. Spectral contributions were discussed considering different degradation mechanisms. Copyright © 2017 Elsevier B.V. All rights reserved.

DNA Methylation and Cancer Diagnosis

PubMed Central

Delpu, Yannick; Cordelier, Pierre; Cho, William C.; Torrisani, Jérôme

2013-01-01

DNA methylation is a major epigenetic modification that is strongly involved in the physiological control of genome expression. DNA methylation patterns are largely modified in cancer cells and can therefore be used to distinguish cancer cells from normal tissues. This review describes the main technologies available for the detection and the discovery of aberrantly methylated DNA patterns. It also presents the different sources of biological samples suitable for DNA methylation studies. We discuss the interest and perspectives on the use of DNA methylation measurements for cancer diagnosis through examples of methylated genes commonly documented in the literature. The discussion leads to our consideration for why DNA methylation is not commonly used in clinical practice through an examination of the main requirements that constitute a reliable biomarker. Finally, we describe the main DNA methylation inhibitors currently used in clinical trials and those that exhibit promising results. PMID:23873296

Crash Modification Factors for Chevrons in Iowa

DOT National Transportation Integrated Search

2018-02-02

Although chevron alignment signs have been utilized for some time along horizontal curves, their effectiveness is not well documented. The Crash Modification Factors Clearinghouse includes crash modification factors (CMFs) for chevrons from 0.41 to 1...

Your Official U.S. Constitution Sign-On Information and Documents.

ERIC Educational Resources Information Center

National Conference of Christians and Jews, New York, NY.

These learning materials are centered around the idea that each individual should "sign" the U.S. Constitution. A facsimile of the U.S. Constitution is included in each learning packet for students to sign. Section 1 contains five teaching modules on the constitutional process that can be used with any subject. The first two modules,…

Who Said Learning about the Constitution Isn't Fun? Active Lessons on the U.S. Constitution for Junior and Senior High School Students. Lessons created by participants at "Congress and the Constitution: A Summer Institute for Teachers" (Ontario, California, 1988).

ERIC Educational Resources Information Center

Cramer, Elizabeth, Ed.; Hill, Margaret, Ed.

Twenty-eight lesson plans developed by California teachers who attended a summer institute on Congress and the Constitution are presented in this document. Sample lesson plan titles are: (1) "Geopolitics and the Constitution," (2) "Judicial Review," (3) "Electoral College and the Constitution," (4) "First…

Air Conditioning Modifications to AMG Buses

DOT National Transportation Integrated Search

1983-12-01

This report presents the documentation and evaluation of air conditioning system modifications devised by Miami (Florida) Metrobus and Los Angeles SCRTD for the AM General Model B bus. The objective of these modifications was to reduce the frequency ...

Pilot-testing an adverse drug event reporting form prior to its implementation in an electronic health record.

PubMed

Chruscicki, Adam; Badke, Katherin; Peddie, David; Small, Serena; Balka, Ellen; Hohl, Corinne M

2016-01-01

Adverse drug events (ADEs), harmful unintended consequences of medication use, are a leading cause of hospital admissions, yet are rarely documented in a structured format between care providers. We describe pilot-testing structured ADE documentation fields prior to integration into an electronic medical record (EMR). We completed a qualitative study at two Canadian hospitals. Using data derived from a systematic review of the literature, we developed screen mock-ups for an ADE reporting platform, iteratively revised in participatory workshops with diverse end-user groups. We designed a paper-based form reflecting the data elements contained in the mock-ups. We distributed them to a convenience sample of clinical pharmacists, and completed ethnographic workplace observations while the forms were used. We reviewed completed forms, collected feedback from pharmacists using semi-structured interviews, and coded the data in NVivo for themes related to the ADE form. We completed 25 h of clinical observations, and 24 ADEs were documented. Pharmacists perceived the form as simple and clear, with sufficient detail to capture ADEs. They identified fields for omission, and others requiring more detail. Pharmacists encountered barriers to documenting ADEs including uncertainty about what constituted a reportable ADE, inability to complete patient follow-up, the need for inter-professional communication to rule out alternative diagnoses, and concern about creating a permanent record. Paper-based pilot-testing allowed planning for important modifications in an ADE documentation form prior to implementation in an EMR. While paper-based piloting is rarely reported prior to EMR implementations, it can inform design and enhance functionality. Piloting with other groups of care providers and in different healthcare settings will likely lead to further revisions prior to broader implementations.

Spatial distribution of erosion and deposition during a glacier surge: Brúarjökull, Iceland

NASA Astrophysics Data System (ADS)

Korsgaard, Niels J.; Schomacker, Anders; Benediktsson, Ívar Örn; Larsen, Nicolaj K.; Ingólfsson, Ólafur; Kjær, Kurt H.

2015-12-01

Time-series of digital elevation models (DEMs) of the forefield of the Brúarjökull surge-type glacier in Iceland were used to quantify the volume of material that was mobilized by the 1963-1964 surge. The DEMs were produced by stereophotogrammetry on aerial photographs from before the surge (1961) and after (1988 and 2003). The analysis was performed on two DEMs of Difference (DoDs), i.e., a 1961-2003 DoD documenting the impact of the surge and a 1988-2003 DoD documenting the post-surge modification of the juvenile surging glacier landsystem. Combined with a digital geomorphological map, the DoDs allow us to quantify the impact of the surge on a landsystem scale down to individual landforms. A total of 34.2 ± 11.3 × 106 m3 of material was mobilized in the 30.7-km2 study area as a result of the most recent surge event. Of these, 17.4 ± 6.6 × 106 m3 of the material were eroded and 16.8 ± 4.7 × 106 m3 were deposited. More than half of the deposited volume was ice-cored landforms. This study demonstrates that although the total mobilized mass volume is high, the net volume gain of ice and sediment deposited as landforms in the forefield caused by the surge is low. Furthermore, deposition of new dead-ice from the 1963-1964 surge constitutes as much as 64% of the volume gain in the forefield. The 1988-2003 DoD is used to quantify the melt-out of this dead-ice and other paraglacial modification of the recently deglaciated forefield of Brúarjökull.

Dose modification in e.coli by a constitutive radioprotective agent isolated from m. radiodurans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldstein, Lawrence S.

1972-01-01

A constitutive low molecular weight radioprotective agent has been isolated from a colorless mutant of Micrococcus radiodurans. The effect of radioprotective extract was also investigated in three mutant strains of E.coli B/r differing from one another at a given locus concerned with the repair of radiation induced damage/

Constitutional Issues--Watergate and the Constitution. Teaching with Documents.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

When U.S. President Richard Nixon resigned in 1974 in the wake of the Watergate scandal, it was only the second time that impeachment of a president had been considered. Although the U.S. Constitution has provisions for a person removed from office to be indicted, there are no guidelines in the Constitution about a President who has resigned. The…

77 FR 13997 - Revising Standards Referenced in the Acetylene Standard

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

....S. Department of Labor, 200 Constitution Avenue NW., Washington, DC 20210; telephone: (202) 693-1999.... Department of Labor, 200 Constitution Avenue NW., Washington, DC 20210; telephone: (202) 693-2260; fax: (202..., 200 Constitution Avenue NW., Washington, DC 20210, authorized the preparation of this document. OSHA...

Documents related to Proposed Class II injection well permit modification MI-147-2D-0014

EPA Pesticide Factsheets

Public notice for proposed modification of permit number MI-147-2D-0014 (St. Clair County, MI). The proposed modification would change the injection zone, the construction, and reduce the injection pressure.

Constitutive Behavior and Modeling of Al-Cu Alloy Systems

DTIC Science & Technology

2013-05-01

Mechanical Threshold of Dynamically Deformed Copper and Nitronic 40 ." Journal de Physique, 1985: 25- 34. Gama, B. A., S. L. Lopatnikov, and J. W. G...38 3. MODIFIED ZERILLI-ARMSTRONG MODEL .................................... 40 3.1 Introduction... 40 3.2 Former Modifications to ZA Model by Zerilli and Armstrong .. 42 3.3 Modifications to ZA Model

This Constitution: A Bicentennial Chronicle, Nos. 14-18.

ERIC Educational Resources Information Center

Mann, Shelia, Ed.

1987-01-01

Each issue in this bicentennial series features articles on selected U.S. Constitution topics, along with a section on primary documents and lesson plans or class activities. Issue 14 features: (1) "The Political Economy of the Constitution" (K. Dolbeare; L. Medcalf); (2) "A 'New Historical Whooper': Creating the Art of the…

77 FR 57981 - Constitution Day and Citizenship Day, Constitution Week, 2012

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-18

... than two centuries, our country has drawn enterprising men and women from around the world--individuals... on the basic rights and responsibilities of citizenship, the founding documents from which they were... Constitution, and reaffirm our commitment to the rights and obligations of citizenship in this great Nation...

The Constitution and Citizenship Education.

ERIC Educational Resources Information Center

Shoemaker, Rebecca S.

The paper takes the position that the study and understanding of the United States Constitution should be a critical part of citizenship education, especially as its Bicentennial approaches. Several factors suggest that the Constitution has become the most durable document of its kind in history, and that its teaching should be centered in both…

From "Conflict" to "Constitutional Question": Transformations in Early American Public Discourse.

ERIC Educational Resources Information Center

Zarefsky, David; Gallagher, Victoria J.

1990-01-01

Suggests that the United States Constitution contains nearly universal concepts but also ambiguities which trigger conflicts. Describes the evolution of the document through its framing and through controversy surrounding the Alien and Sedition Acts, state nullification of federal action, and secession. Concludes that the Constitution provides a…

29 CFR 452.19 - Executive functions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... identified as an officer under the constitution and bylaws of the organization. Authorization to perform such functions need not be contained in any provision of the constitution or bylaws or other document but may be... governing body) or if the constitution or bylaws of the union designate such positions as officers. ...

29 CFR 452.19 - Executive functions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... identified as an officer under the constitution and bylaws of the organization. Authorization to perform such functions need not be contained in any provision of the constitution or bylaws or other document but may be... governing body) or if the constitution or bylaws of the union designate such positions as officers. ...

29 CFR 452.19 - Executive functions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... identified as an officer under the constitution and bylaws of the organization. Authorization to perform such functions need not be contained in any provision of the constitution or bylaws or other document but may be... governing body) or if the constitution or bylaws of the union designate such positions as officers. ...

Post-translational modifications in secreted peptide hormones in plants.

PubMed

Matsubayashi, Yoshikatsu

2011-01-01

More than a dozen secreted peptides are now recognized as important hormones that coordinate and specify cellular functions in plants. Recent evidence has shown that secreted peptide hormones often undergo post-translational modification and proteolytic processing, which are critical for their function. Such 'small post-translationally modified peptide hormones' constitute one of the largest groups of peptide hormones in plants. This short review highlights recent progress in research on post-translationally modified peptide hormones, with particular emphasis on their structural characteristics and modification mechanisms.

AI-MSG modification work plan. [LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Page, J.P.

1973-08-20

This document contains the Work Plan for the modification of the AI Steam Generator for tests in Large Leak Test Rig. This Work Plan describes the objectives, scope of work, schedule and manpower, end items, and meetings and reports required for the modification.

Knowing It by Heart: Americans Consider the Constitution and Its Meaning. A Report by Public Agenda for the National Constitution Center.

ERIC Educational Resources Information Center

Farkas, Steve; Johnson, Jean; Duffett, Ann

A study conducted by Public Agenda Foundation, in partnership with the National Constitution Center, examined what typical adults know and believe about the U.S. Constitution, probed what they understand their rights and civic responsibilities to be, and reported their views on the document's importance and relevance in their lives today. The…

25 CFR 81.18 - Manner of voting.

Code of Federal Regulations, 2013 CFR

2013-04-01

... the adoption of a constitution, the ratification of a charter, or the amendment of such documents... further, that no charter shall be considered ratified if the proposed constitution is not adopted and...

Equality: Constitutional Update. Bar/School Partnership Programs Series.

ERIC Educational Resources Information Center

American Bar Association, Chicago, IL. Special Committee on Youth Education for Citizenship.

The second in a special four-part series of law-school partnership handbooks on constitutional themes, this document focuses on equality. "Equality--the Forgotten Word" (J. A. Hughes) discusses what has been considered the U.S. Constitution's one flaw, its failure to abolish slavery, and the remedy to that flaw, the Fourteenth Amendment.…

Why it's time to recognise Indigenous peoples in the Constitution.

PubMed

Williams, George

2015-06-01

This article provides an overview of why it is proposed that the Australian Constitution be changed to recognise Aboriginal and Torres Strait Islander peoples. It then establishes what changes are needed to the Constitution. The Australian Constitution fails to recognise Indigenous peoples, and still enables discrimination against them. This provides a sound case for changing the document. © The Royal Australian and New Zealand College of Psychiatrists 2015.

Recommendations and Justifications for Modifications To Downgrade Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order, Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Birney, Cathleen; Krauss, Mark J

This document is part of an effort to reevaluate 37 FFACO and Administrative URs against the current Soils Risk-Based Corrective Action Evaluation Process. After reviewing 37 existing FFACO and Administrative URs, 11 URs addressed in this document have sufficient information to determine that these current URs may be downgraded to Administrative URs based on the RBCA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RBCA criteria.

New York and the Union: Contributions to the American Constitutional Experience.

ERIC Educational Resources Information Center

Schechter, Stephen L., Ed.; Bernstein, Richard B., Ed.

This book provides a detailed account of the role of the state of New York in the history and development of the United States Constitution. The document consists of some 68 essays, in addition to a foreword, editors' introduction, and chronology of bicentennial dates. Part 1, "Origins of Constitutionalism in New York," addresses such…

We the People: Law-Related Lessons on Teaching the Constitution.

ERIC Educational Resources Information Center

Constitutional Rights Foundation, Chicago, IL.

The Unites States Constitution and the Bill of Rights set forth the basic principles of the U.S. democratic constitutional order. It is from these documents that the fundamental political concepts of the United States are derived. The program presented here was developed for junior high school students and is intended to combat the apathy toward…

USSR Report, USA: Economics, Politics, Ideology, No. 9. September 1984.

DTIC Science & Technology

1984-12-10

refe- rences to the constitutional principle of the separation of powers and insisted on the effective exercise of powers by the Congress and the...authors of the constitution did not have our discomfort in mind when they composed this document. They wanted accounta- bility and the separation of powers . They...integral part of the constitutional separation of powers . The legislative veto, in accordance with the constitution, could be regarded as a legislative

NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE (NELAC): CONSTITUTION, BYLAWS, AND STANDARDS

EPA Science Inventory

The principles and operating procedures for the National Environmental Laboratory Accreditation Conference (NELAC) are contained in the NELAC Constitution and Bylaws. The major portion of this document (standards) contains detailed requirements for accrediting environmental labo...

[What is dementia? 4. Dementia and law].

PubMed

de Martel, Annick

2003-06-01

Dementia is a basic point of French civil and criminal law. It justifies the supervision or guardianship of demented subjects and the cancelation of judicial documents. It constitutes a cause of non-responsability in criminal law but the patient with dementia is required to compensate the financial and moral damage of his(her) deeds. However, in the past few years, the term of dementia has been withdrawn from the law and replaced by notions such as mental disorder, thought disturbances... The reason for this modification is that dementia is no more considered as a general condition but as a specific mental disorder. Moreover, new legal concepts result in a better distinction between the mental disorder and its consequences on the behavior of the patient, hence a better adjustment for judicial problem solving. Nevertheless, the term of dementia remains still commonly used in case law on account of its emotive power. Due to this persistent use, should we doubt that dementia is... a disease?

48 CFR 227.7205 - Contracts for special works.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Computer Software and Computer Software Documentation 227.7205 Contracts for special works. (a) Use the... a specific need to control the distribution of computer software or computer software documentation..., modification, reproduction, release, performance, display, or disclosure of such software or documentation. Use...

48 CFR 227.7205 - Contracts for special works.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Computer Software and Computer Software Documentation 227.7205 Contracts for special works. (a) Use the... a specific need to control the distribution of computer software or computer software documentation..., modification, reproduction, release, performance, display, or disclosure of such software or documentation. Use...

NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE; CONSTITUTION, BYLAWS AND STANDARDS: APPROVED MAY 25, 2001

EPA Science Inventory

The principles and operating procedures for the National Environmental Laboratory Accreditation Conference (NELAC) are contained in the NELAC Constitution and Bylaws. The major portion of this document (standards) contains detailed requirements for accrediting environmental labo...

Ordered Rate Constitutive Theories: Development of Rate Constitutive Equations for Solids, Liquids, and Gases

DTIC Science & Technology

2010-08-18

the author(s) and should not contrued as an official Department of the Army position, policy or decision, unless so designated by other documentation...Daniel S. Nunez 0.50 Yong-Ting Ma 0.50 Tristan Moody 0.50 1.50FTE Equivalent: 3Total Number: Names of Post Doctorates PERCENT_SUPPORTEDNAME FTE...demonstrated that the constitutive theory for ordered thermofluids of all orders is indeed rate constitutive theory. The reseach work presented in this chapter

10 CFR 820.36 - Filing, form, and service of documents.

Code of Federal Regulations, 2014 CFR

2014-01-01

... representative. The signature constitutes a representation by the signer that he has read the pleading, letter or other document, that to the best of his knowledge, information and belief, the statements made therein...

10 CFR 820.36 - Filing, form, and service of documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... representative. The signature constitutes a representation by the signer that he has read the pleading, letter or other document, that to the best of his knowledge, information and belief, the statements made therein...

10 CFR 820.36 - Filing, form, and service of documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... representative. The signature constitutes a representation by the signer that he has read the pleading, letter or other document, that to the best of his knowledge, information and belief, the statements made therein...

10 CFR 820.36 - Filing, form, and service of documents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... representative. The signature constitutes a representation by the signer that he has read the pleading, letter or other document, that to the best of his knowledge, information and belief, the statements made therein...

South Florida freight advanced traveler information system : architecture and implementation as built documentation report.

DOT National Transportation Integrated Search

2015-05-01

The primary purpose of the As Built Documentation is to provide a description of any modifications made to the original architecture along with justification as to why the architecture was changed. In addition, this documentation provides the followi...

A Method of Retrospective Computerized System Validation for Drug Manufacturing Software Considering Modifications

NASA Astrophysics Data System (ADS)

Takahashi, Masakazu; Fukue, Yoshinori

This paper proposes a Retrospective Computerized System Validation (RCSV) method for Drug Manufacturing Software (DMSW) that relates to drug production considering software modification. Because DMSW that is used for quality management and facility control affects big impact to quality of drugs, regulatory agency required proofs of adequacy for DMSW's functions and performance based on developed documents and test results. Especially, the work that explains adequacy for previously developed DMSW based on existing documents and operational records is called RCSV. When modifying RCSV conducted DMSW, it was difficult to secure consistency between developed documents and test results for modified DMSW parts and existing documents and operational records for non-modified DMSW parts. This made conducting RCSV difficult. In this paper, we proposed (a) definition of documents architecture, (b) definition of descriptive items and levels in the documents, (c) management of design information using database, (d) exhaustive testing, and (e) integrated RCSV procedure. As a result, we could conduct adequate RCSV securing consistency.

Histone modification: cause or cog?

PubMed

Henikoff, Steven; Shilatifard, Ali

2011-10-01

Histone modifications are key components of chromatin packaging but whether they constitute a 'code' has been contested. We believe that the central issue is causality: are histone modifications responsible for differences between chromatin states, or are differences in modifications mostly consequences of dynamic processes, such as transcription and nucleosome remodeling? We find that inferences of causality are often based on correlation and that patterns of some key histone modifications are more easily explained as consequences of nucleosome disruption in the presence of histone modifying enzymes. We suggest that the 35-year-old DNA accessibility paradigm provides a mechanistically sound basis for understanding the role of nucleosomes in gene regulation and epigenetic inheritance. Based on this view, histone modifications and variants contribute to diversification of a chromatin landscape shaped by dynamic processes that are driven primarily by transcription and nucleosome remodeling. Copyright © 2011 Elsevier Ltd. All rights reserved.

Permit application modifications

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-11-01

This document contains the Permit Application Modifications for the Y-12 Industrial Landfill V site on the Oak Ridge Reservation. These modifications include the assessment of stability of the proposed Landfill V under static and loading conditions. Analyses performed include the general slope stability, veneer stability of the bottom liner and cover system, and a liquefaction potential assessment of the foundation soils.

Addendum to the Closure Report for Corrective Action Unit 357: Mud Pits and Waste Dump, Nevada Test Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krauss, Mark J

This document constitutes an addendum to the Closure Report for Corrective Action Unit 357: Mud Pits and Waste Dump, Nevada Test Site, Nevada as described in the document Recommendations and Justifications To Remove Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order dated September 2013. The Use Restriction Removal document was approved by the Nevada Division of Environmental Protection on October 16, 2013. The approval of the UR Removal document constituted approval of each of the recommended UR removals. In conformance with the UR Removal document, thismore » addendum consists of: This page that refers the reader to the UR Removal document for additional information The cover, title, and signature pages of the UR Removal document The NDEP approval letter The corresponding section of the UR Removal document This addendum provides the documentation justifying the cancellation of the UR for CAS 04-26-03, Lead Bricks. This UR was established as part of FFACO corrective actions and was based on the presence of lead contamination at concentrations greater than the action level established at the time of the initial investigation.« less

Addendum to the Corrective Action Decision Document/Closure Report for Corrective Action Unit 529: Area 25 Contaminated Materials, Nevada Test Site, Nevada, Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krauss, Mark J

This document constitutes an addendum to the Corrective Action Decision Document/Closure Report for Corrective Action Unit 529: Area 25 Contaminated Materials, Nevada Test Site, Nevada as described in the document Recommendations and Justifications To Remove Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order dated September 2013. The Use Restriction (UR) Removal document was approved by the Nevada Division of Environmental Protection on October 16, 2013. The approval of the UR Removal document constituted approval of each of the recommended UR removals. In conformance with the URmore » Removal document, this addendum consists of: This page that refers the reader to the UR Removal document for additional information The cover, title, and signature pages of the UR Removal document The NDEP approval letter The corresponding section of the UR Removal document This addendum provides the documentation justifying the cancellation of the UR for CAS 25-23-17, Contaminated Wash (Parcel H). This UR was established as part of FFACO corrective actions and was based on the presence of total petroleum hydrocarbon diesel-range organics contamination at concentrations greater than the NDEP action level at the time of the initial investigation.« less

The Constitutional Heritage.

ERIC Educational Resources Information Center

Baxter, Maurice

Changing political, social, economic, and intellectual conditions over the past two hundred years have demanded innovation and adjustment of legal doctrine, thus giving the United States Constitution a character which the framers of the document could not have predicted. Historically, one must not only understand developments since 1787 but also…

Plant cell walls to ethanol.

USDA-ARS?s Scientific Manuscript database

Conversion of plant cell walls to ethanol constitutes generation 2 bioethanol production. The process consists of several steps: biomass selection/genetic modification, physiochemical pretreatment, enzymatic saccharification, fermentation, and separation. Ultimately, it is desired to combine as man...

Investigation Concerning the Modification of the University of Illinois Computerized Serials Book Catalog to Achieve an Operative System at the University of Colorado Libraries.

ERIC Educational Resources Information Center

Dougherty, Richard M.; Stephens, James G.

The objectives of the study were to record: (1) the problems encountered in interpreting and using the Illinois program documentation; (2) the modifications required to reconcile system incompatibilities and inefficiencies due to different computer configurations; (3) the input instruction modifications made to accommodate local library processing…

Vulnerability Analyst’s Guide to Geometric Target Description

DTIC Science & Technology

1992-09-01

not constitute indorsement of any commercial product. Form Approved REPORT DOCUMENTATION PAGE OMB No. 0704-O,8 public reporting burden for this...46 5.3 Surrogacy ..............................................46 5.4 Specialized Targets......................................46 5.5... commercially available documents for other large-scale software. The documentation is not a BRL technical report, but can be obtained by contacting

75 FR 41530 - Petitions for Modification; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-16

... DEPARTMENT OF LABOR Mine Safety and Health Administration Petitions for Modification; Correction AGENCY: Mine Safety and Health Administration, Labor. ACTION: Notice; correction. SUMMARY: The Mine Safety and Health Administration (MSHA) published a document in the Federal Register of June 17, 2010...

Design Package for Fuel Retrieval System Fuel Handling Tool Modification

DOE Office of Scientific and Technical Information (OSTI.GOV)

TEDESCHI, D.J.

This design package documents design, fabrication, and testing of new stinger tool design. Future revisions will document further development of the stinger tool and incorporate various developmental stages, and final test results.

Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.

PubMed

Malkus, Kristen A; Tsika, Elpida; Ischiropoulos, Harry

2009-06-05

While numerous hypotheses have been proposed to explain the molecular mechanisms underlying the pathogenesis of neurodegenerative diseases, the theory of oxidative stress has received considerable support. Although many correlations have been established and encouraging evidence has been obtained, conclusive proof of causation for the oxidative stress hypothesis is lacking and potential cures have not emerged. Therefore it is likely that other factors, possibly in coordination with oxidative stress, contribute to neuron death. Using Parkinson's disease (PD) as the paradigm, this review explores the hypothesis that oxidative modifications, mitochondrial functional disruption, and impairment of protein degradation constitute three interrelated molecular pathways that execute neuron death. These intertwined events are the consequence of environmental exposure, genetic factors, and endogenous risks and constitute a "Bermuda triangle" that may be considered the underlying cause of neurodegenerative pathogenesis.

Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle

PubMed Central

Malkus, Kristen A; Tsika, Elpida; Ischiropoulos, Harry

2009-01-01

While numerous hypotheses have been proposed to explain the molecular mechanisms underlying the pathogenesis of neurodegenerative diseases, the theory of oxidative stress has received considerable support. Although many correlations have been established and encouraging evidence has been obtained, conclusive proof of causation for the oxidative stress hypothesis is lacking and potential cures have not emerged. Therefore it is likely that other factors, possibly in coordination with oxidative stress, contribute to neuron death. Using Parkinson's disease (PD) as the paradigm, this review explores the hypothesis that oxidative modifications, mitochondrial functional disruption, and impairment of protein degradation constitute three interrelated molecular pathways that execute neuron death. These intertwined events are the consequence of environmental exposure, genetic factors, and endogenous risks and constitute a "Bermuda triangle" that may be considered the underlying cause of neurodegenerative pathogenesis. PMID:19500376

[Surface grafting modification and stabilization of Kevlar fiber].

PubMed

Zheng, Yu-ying; Fu, Ming-lian; Wang, Can-yao; Wang, Liang-en

2005-11-01

Chemical disposal was used to bring the activity group onto the surface of Kevlar fiber for the purpose of surface grafting modification. The interfacial constitution of the grafting of toluene-2,4-diisocyanate (TDI) onto Kevlar fiber was determined by Fourier transform infrared spectroscopy. In the mean time, hexyl-lactam stabilization and poly-glycol (400, PEG) stabilization on the grafted product were also studied. The effects of different nTDI:nPEG ratios on the production's interfacial constitution was analysed. It is concluded that the stabilization took place on the surface. The intensity of the bands relented at about 3300 cm(-1) and was reinforced at about 1700-1720 cm(-1) when the ratio of nTDI:nPEG = 1:3, but when the ratio is 1:1 and 1:2, the bands at about 3 300 and 1700-1720 cm(-1) are almost the same.

The Obligations of American Citizenship: A Historical Perspective.

ERIC Educational Resources Information Center

Murphy, Paul L.

1983-01-01

Historical antecedents of modern constitutionalism are examined, and the concepts of citizen participation, civic responsibility, and limitation of government are explained in that context. Students must be exposed to the constitutional basics--why the document is retained, what values it incorporates, and where it has succeeded and failed. (PP)

We the People: Elementary Pre-Service Teachers and Constitutional Readability

ERIC Educational Resources Information Center

Meier, Lori T.; Keith, Karin J.; Dwyer, Edward J.

2014-01-01

In light of increasing mandates to incorporate close reading of primary source historical documents at the elementary level, this study explored the reading difficulty level of the US Constitution with preservice elementary teachers using a traditional cloze assessment procedure. While best practice pedagogy of social studies has long included…

A Course on the Constitution.

ERIC Educational Resources Information Center

Baker, Thomas E.; Viator, James E.

1990-01-01

A law school course about the Constitution's history and theory in the era of its framers is described. The course explores their learning, ideas, and vision and examines the document's intellectual background, writing and ratification processes, major issues and alternatives confronted, and ideas about its function as a form of government. (MSE)

Modification of the Integrated Sasang Constitutional Diagnostic Model

PubMed Central

Nam, Jiho

2017-01-01

In 2012, the Korea Institute of Oriental Medicine proposed an objective and comprehensive physical diagnostic model to address quantification problems in the existing Sasang constitutional diagnostic method. However, certain issues have been raised regarding a revision of the proposed diagnostic model. In this paper, we propose various methodological approaches to address the problems of the previous diagnostic model. Firstly, more useful variables are selected in each component. Secondly, the least absolute shrinkage and selection operator is used to reduce multicollinearity without the modification of explanatory variables. Thirdly, proportions of SC types and age are considered to construct individual diagnostic models and classify the training set and the test set for reflecting the characteristics of the entire dataset. Finally, an integrated model is constructed with explanatory variables of individual diagnosis models. The proposed integrated diagnostic model significantly improves the sensitivities for both the male SY type (36.4% → 62.0%) and the female SE type (43.7% → 64.5%), which were areas of limitation of the previous integrated diagnostic model. The ideas of these new algorithms are expected to contribute not only to the scientific development of Sasang constitutional medicine in Korea but also to that of other diagnostic methods for traditional medicine. PMID:29317897

Documents and Symbols of American Freedom. Elementary Grade Activity. Schools of California Online Resources for Education (SCORE): Connecting California's Classrooms to the World.

ERIC Educational Resources Information Center

Hutchens, Dorothy

This lesson plan for elementary-age children studies some of the primary source documents and symbols of freedom which were and are important for the nation. The lesson plan uses the following documents: "The Mayflower Compact"; "The Declaration of Independence"; "The Constitution"; and the "Bill of Rights."…

From Oral Ceremony to Written Document: The Transitional Language of Anglo-Saxon Wills.

ERIC Educational Resources Information Center

Danet, Brenda; Bogoch, Bryna

1992-01-01

Presents theoretical discussion of the emergence of linguistic features of documents that indicate society is moving toward a view of writing as a form of constitutive social action and of written documents as autonomous material objects having a life of their own. Linguistic features of Anglo-Saxon wills are shown to differ from those of modern…

Listener Responses According to Stuttering Self-Acknowledgment and Modification

ERIC Educational Resources Information Center

Lee, Kyungjae; Manning, Walter H.

2010-01-01

Given the well-documented understanding that stuttering behavior elicits stereotypically negative responses from listeners, two experiments explored the equivocal results of earlier investigations concerning the potential for self-acknowledgment and modification of stuttering to elicit positive responses from naive (unfamiliar with stuttering)…

48 CFR 43.204 - Administration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 43.204 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT CONTRACT MODIFICATIONS Change Orders 43.204 Administration. (a) Change order documentation. When change orders are not forward priced, they require two documents: the change order and a supplemental agreement...

40 CFR 141.25 - Analytical methods for radioactivity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Monitoring and Analytical Requirements... obtaining these documents can be obtained from the Safe Drinking Water Hotline at 800-426-4791. Documents may be inspected at EPA's Drinking Water Docket, EPA West, 1301 Constitution Avenue, NW., Room 3334...

40 CFR 141.25 - Analytical methods for radioactivity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Monitoring and Analytical Requirements... obtaining these documents can be obtained from the Safe Drinking Water Hotline at 800-426-4791. Documents may be inspected at EPA's Drinking Water Docket, EPA West, 1301 Constitution Avenue, NW., Room 3334...

40 CFR 141.25 - Analytical methods for radioactivity.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Monitoring and Analytical Requirements... obtaining these documents can be obtained from the Safe Drinking Water Hotline at 800-426-4791. Documents may be inspected at EPA's Drinking Water Docket, EPA West, 1301 Constitution Avenue, NW., Room 3334...

40 CFR 141.25 - Analytical methods for radioactivity.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Monitoring and Analytical Requirements... obtaining these documents can be obtained from the Safe Drinking Water Hotline at 800-426-4791. Documents may be inspected at EPA's Drinking Water Docket, EPA West, 1301 Constitution Avenue, NW., Room 3334...

3 CFR - Presidential Signing Statements

Code of Federal Regulations, 2010 CFR

2010-01-01

... 3 The President 1 2010-01-01 2010-01-01 false Presidential Signing Statements Presidential Documents Other Presidential Documents Memorandum of March 9, 2009 Presidential Signing Statements Memorandum for the Heads of Executive Departments and Agencies For nearly two centuries, Presidents have issued statements addressing constitutional or other...

Biblical Antecedents to Fiscal Equity: Policy Implications for Education.

ERIC Educational Resources Information Center

Furst, Lyndon G.

Most arguments for fiscal equity in financing America's schools have been based on constitutional provisions and on the socio-political dogma that underlies a democratic society. This paper approaches the subject using as its theoretical basis a document even more basic to the founding of the republic than the Constitution--the Bible. Using the…

The Purpose, Structure and Limitations of the Electoral College

ERIC Educational Resources Information Center

Webster, Gerald R.

2016-01-01

The U.S. Constitution was drafted in Philadelphia from late May to mid-September 1787. The fifty-five delegates to the Constitutional Convention gathered to revise the Articles of Confederation but soon decided to write an entirely new document. These "Framers" were committed to forming a representative democracy, but their largely…

A Compilation of Laws Pertaining to Indians. State of Maine, July 1976.

ERIC Educational Resources Information Center

Maine State Dept. of Indian Affairs, Augusta.

Compiled from the Maine Revised Statutes of 1964, the Constitution of Maine, and the current Resolves and Private and Special Laws, this document constitutes an update to a previous publication (January 1974), correcting errors and adding amendments through 1976. This compilation of laws pertaining to American Indians includes statutes on the…

The News Media and the Government: Clash of Concentrated Power.

ERIC Educational Resources Information Center

Freedom House, Inc., New York, NY.

This document brings together news media and constitutional law specialists with past and present government officials to define the areas of conflict and the operative constitutional rules and to devise ways to maximize the flow of information to the public without destructive confrontations between the media and government. Contents include:…

Formative Evaluation of Project "TEAM" (Teens Making Environment and Activity Modifications)

ERIC Educational Resources Information Center

Kramer, Jessica M.; Roemer, Kristin; Liljenquist, Kendra; Shin, Julia; Hart, Stacy

2014-01-01

Research documents the negative impact of physical and social environmental barriers on engagement in school, work, and the community for youth with intellectual and /or developmental disabilities (IDD). Project "TEAM" (Teens making Environment and Activity Modifications) was designed to teach youth to systematically identify…

78 FR 53466 - Modification of Two National Customs Automation Program (NCAP) Tests Concerning Automated...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Modification of Two National Customs Automation Program (NCAP) Tests Concerning Automated Commercial Environment (ACE) Document Image System (DIS) and Simplified Entry (SE); Correction AGENCY: U.S. Customs and Border Protection, Department...

Integration of immunological aspects in the European Human Embryonic Stem Cell Registry.

PubMed

Borstlap, Joeri; Kurtz, Andreas

2008-05-01

The immunological properties of stem cells are of increasing importance in regenerative medicine. Immunomodulatory mechanisms seem to play an important role not only with respect to the understanding of underlying mechanisms of autologous versus allogenic therapeutic approaches, but also for endogeneous tissue regeneration. The newly established European human embryonic stem cell registry (hESCreg) offers an international database for the registration, documentation and characterisation of human embryonic stem cells (hESC) and their use. By doing so, hESCreg aims to develop a model procedure for further standardisation efforts in the field of stem cell research and regenerative medicine, and eventually the registry may lead to a repository of therapy-related information. Currently the stem cell characterisation data acquired by the registry are divided into several categories such as cell derivation, culture conditions, genetic constitution, stem cell marker expression and degree of modification. This article describes immunological aspects of stem cell characterisation and explores the layout and relevance of a possible additional section to the hESCreg repository to include immunological characteristics of human embryonic stem cells.

Regulating the Regulator: Post-Translational Modification of Ras

PubMed Central

Ahearn, Ian M.; Haigis, Kevin; Bar-Sagi, Dafna; Philips, Mark R.

2013-01-01

Ras proteins are monomeric GTPases that act as binary molecular switches to regulate a wide range of cellular processes. The exchange of GTP for GDP on Ras is regulated by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs), which regulate the activation state of Ras without covalently modifying it. In contrast, post-translational modifications (PTMs) of Ras proteins direct them to various cellular membranes and, in some cases, modulate GTP–GDP exchange. Important Ras PTMs include the constitutive and irreversible remodelling of its C-terminal CAAX motif by farnesylation, proteolysis and methylation, reversible palmitoylation, and conditional modifications including phosphorylation, peptidyl-proly isomerisation, mono- and di-ubiquitination, nitrosylation, ADP ribosylation and glucosylation. PMID:22189424

40 CFR 132.1 - Scope, purpose, and availability of documents.

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROGRAMS WATER QUALITY GUIDANCE FOR THE GREAT LAKES SYSTEM § 132.1 Scope, purpose, and availability of documents. (a) This part constitutes the Water Quality Guidance for the Great Lakes System (Guidance... identifies minimum water quality standards, antidegradation policies, and implementation procedures for the...

40 CFR 132.1 - Scope, purpose, and availability of documents.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROGRAMS WATER QUALITY GUIDANCE FOR THE GREAT LAKES SYSTEM § 132.1 Scope, purpose, and availability of documents. (a) This part constitutes the Water Quality Guidance for the Great Lakes System (Guidance... identifies minimum water quality standards, antidegradation policies, and implementation procedures for the...

40 CFR 132.1 - Scope, purpose, and availability of documents.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS WATER QUALITY GUIDANCE FOR THE GREAT LAKES SYSTEM § 132.1 Scope, purpose, and availability of documents. (a) This part constitutes the Water Quality Guidance for the Great Lakes System (Guidance... identifies minimum water quality standards, antidegradation policies, and implementation procedures for the...

40 CFR 132.1 - Scope, purpose, and availability of documents.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS WATER QUALITY GUIDANCE FOR THE GREAT LAKES SYSTEM § 132.1 Scope, purpose, and availability of documents. (a) This part constitutes the Water Quality Guidance for the Great Lakes System (Guidance... identifies minimum water quality standards, antidegradation policies, and implementation procedures for the...

PSD Definition of Modification

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Significant Modification to LAER/PSD Application: Ocean Peaking Power, L.P.

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

B. F. Goodrich - PSD modification

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

PSD Determination: Sun Oil Company and the Definition of Major Modification

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Enhancing Documentation of Pressure Ulcer Prevention Interventions: A Quality Improvement Strategy to Reduce Pressure Ulcers.

PubMed

Jacobson, Therese M; Thompson, Susan L; Halvorson, Anna M; Zeitler, Kristine

2016-01-01

Prevention of hospital-acquired pressure ulcers requires the implementation of evidence-based interventions. A quality improvement project was conducted to provide nurses with data on the frequency with which pressure ulcer prevention interventions were performed as measured by documentation. Documentation reports provided feedback to stakeholders, triggering reminders and reeducation. Intervention reports and modifications to the documentation system were effective both in increasing the documentation of pressure ulcer prevention interventions and in decreasing the number of avoidable hospital-acquired pressure ulcers.

Revised Draft Policy on Permit Modifications and Extensions

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Clarification of Title I Modifications

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Opinion On Whether Making a Bypass Stack Functional Constitutes Routine Repair and Maintenance

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

30 CFR 44.6 - Service.

Code of Federal Regulations, 2010 CFR

2010-07-01

... RULES OF PRACTICE FOR PETITIONS FOR MODIFICATION OF MANDATORY SAFETY STANDARDS General § 44.6 Service..., the Office of the Solicitor, Department of Labor. (b) All documents filed subsequent to a petition for... a petition for modification under these rules shall file proof of service in the form of a return...

76 FR 37136 - Post-Entry Amendment (PEA) Processing Test: Modification, Clarification, and Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

.... Customs and Border Protection's (CBP's) Post-Entry Amendment (PEA) Processing test, which allows the...: The Post-Entry Amendment (PEA) Processing test modification set forth in this document is effective...: Background I. Post-Entry Amendment Processing Test Program The Post-Entry Amendment (PEA) Processing test...

Modification of Baselines for Gasoline Produced or Imported for Use in Hawaii, Alaska, and U.S. Territories Additional Resources

EPA Pesticide Factsheets

This documents for modifications to fuel regulations to allow refiners and importers of conventional gasoline used in Hawaii, Alaska and U.S. Territories to petition EPA to change the way in which they calculate emissions from such gasoline.

Retrofit and verification test of a 30-cm ion thruster

NASA Technical Reports Server (NTRS)

Dulgeroff, C. R.; Poeschel, R. L.

1980-01-01

Twenty modifications were found to be necessary and were approved by design review. These design modifications were incorporated in the thruster documents (drawings and procedures) to define the J series thruster. Sixteen of the design revisions were implemented in a 900 series thruster by retrofit modification. A standardized set of test procedures was formulated, and the retrofit J series thruster design was verified by test. Some difficulty was observed with the modification to the ion optics assembly, but the overall effect of the design modification satisfies the design objectives. The thruster was tested over a wide range of operating parameters to demonstrate its capabilities.

Covalent Surface Modifications of Carbon Nanotubes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pavia Sanders, Adriana; O'Bryan, Greg

A report meant to document the chemistries investigated by the author for covalent surface modification of CNTs. Oxidation, cycloaddition, and radical reactions were explored to determine their success at covalently altering the CNT surface. Characterization through infrared spectroscopy, Raman spectroscopy, and thermo gravimetric analysis was performed in order to determine the success of the chemistries employed. This report is not exhaustive and was performed for CNT surface modification exploration as it pertains to the "Next Gen" project.

The Discursive Constitution of the UK Alcohol Problem in "Safe, Sensible, Social": A Discussion of Policy Implications

ERIC Educational Resources Information Center

Hackley, Chris; Bengry-Howell, Andrew; Griffin, Christine; Mistral, Willm; Szmigin, Isabelle

2008-01-01

In this article, we critically reflect on the constitution of the UK's alcohol problem in the government's "Safe, Social, Sensible" policy document, referring to findings from a 3-year ESRC funded study on young people, alcohol and identity. We suggest that discursive themes running throughout "Safe, Sensible, Social" include…

Lessons on the Constitution. Supplements to High School Courses in American History, Government and Civics.

ERIC Educational Resources Information Center

Patrick, John J.; Remy, Richard C.

These curriculum materials about various aspects of the United States Constitution are designed as supplements to high school courses in history, civics, and government. They include 60 original lessons for students, accompanied by lesson plans for teachers, and are divided into five chapters. Chapter I, "Documents of Freedom" includes…

Illustrative Bylaws for Public College and University Governing Boards. Board Basics

ERIC Educational Resources Information Center

Ingram, Tom; Johnson, Neal

2005-01-01

Bylaws constitute one of the most important legal documents in the portfolio of a public college or university board. They articulate the board?s responsibilities and establish the "rules" by which the board organizes itself to do its work. Bylaws begin where a public institution's statutes or constitutional provisions leave off. They build on…

29 CFR 1607.15 - Documentation of impact and validity evidence.

Code of Federal Regulations, 2010 CFR

2010-07-01

... national origin group (see section 4 above) constituting more than two percent (2%) of the labor force in... origin (see § 4 above) if one race or national origin group in the relevant labor area constitutes more... selection process for that job has an adverse impact on any of the groups for which records are called for...

Fundamental Laws of the State: The Spanish Constitution.

ERIC Educational Resources Information Center

Ministerio de Informacion y Turismo, Madrid (Spain).

This political document is introduced by the head of the Spanish State, His Excellency Don Francisco Franco Bahamonde in a speech given on 22 November 1966 to the session of the Spanish Cores. The speech outlines in general terms the political and philosophical ideals of His Excellency. The Constitution is presented in several sections including:…

A method for automatically abstracting visual documents

NASA Technical Reports Server (NTRS)

Rorvig, Mark E.

1994-01-01

Visual documents--motion sequences on film, videotape, and digital recording--constitute a major source of information for the Space Agency, as well as all other government and private sector entities. This article describes a method for automatically selecting key frames from visual documents. These frames may in turn be used to represent the total image sequence of visual documents in visual libraries, hypermedia systems, and training algorithm reduces 51 minutes of video sequences to 134 frames; a reduction of information in the range of 700:1.

3 CFR - Continuation of the National Emergency With Respect to Iran

Code of Federal Regulations, 2010 CFR

2010-01-01

... national security, foreign policy, and economy of the United States constituted by the situation in Iran... to Iran Presidential Documents Other Presidential Documents Notice of November 12, 2009 Continuation of the National Emergency With Respect to Iran On November 14, 1979, by Executive Order 12170, the...

12 CFR 308.24 - Scope of document discovery.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Scope of document discovery. 308.24 Section 308.24 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE RULES OF... the Constitution, any applicable act of Congress, or the principles of common law provide. (d) Time...

12 CFR 390.53 - Scope of document discovery.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Scope of document discovery. 390.53 Section 390.53 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL... deliberative-process privilege, and any other privileges the Constitution, any applicable act of Congress, or...

12 CFR 263.24 - Scope of document discovery.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Scope of document discovery. 263.24 Section 263.24 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE... deliberative-process privilege, and any other privileges the Constitution, any applicable act of Congress, or...

Library Laws Handbook: State Laws Relating to Michigan Libraries. [Revised Edition].

ERIC Educational Resources Information Center

Michigan Library, Lansing.

This document presents excerpts and copies of state laws relating to Michigan libraries. The following are included: Preamble of the Constitution of Michigan of 1963; Legislative Council Act (excerpt); Incompatible Public Offices; Freedom of Information Act; Open Meetings Act; Laws, Documents, and Reports (excerpts); Administrative Procedures Act…

Library Laws Handbook: State Laws Relating to Michigan Libraries.

ERIC Educational Resources Information Center

Michigan Library, Lansing.

This document presents excerpts and copies of state laws relating to Michigan libraries. The following are included: the Preamble of the Constitution of Michigan of 1963; Legislative Council Act (excerpt); Incompatible Public Offices; Freedom of Information Act; Open Meetings Act; Laws, Documents, and Reports (excerpts); Administrative Procedures…

Structural modifications induced in dentin by femtosecond laser

NASA Astrophysics Data System (ADS)

Le, Quang-Tri; Bertrand, Caroline; Vilar, Rui

2016-12-01

The structural and chemical modifications induced in dentin by ultrafast laser ablation were studied. The laser experiments were performed with a Yb:KYW chirped-pulse-regenerative amplification laser system (560-fs pulse duration, 1030-nm radiation wavelength), fluences in the range 2 to 14 J/cm2, 1-kHz pulse repetition rate, and 5-mm/s scanning speed. The ablation surfaces were characterized by scanning electron microscopy and Fourier transform infrared spectroscopy. The ablation surfaces produced with 2 J/cm2 presented an irregular morphology with exposed dentinal tubules and no evidence of thermal effects. For 7 and 14 J/cm2, the ablation surfaces were covered by a layer of redeposited ablation debris, consisting mainly of amorphous calcium phosphate. This layer is weakly adherent to the underlying tissue and can be easily removed by ultrasonication, revealing a surface with a morphology similar to the one obtained with 2 J/cm2. The constitution of the dentin ablation surfaces is similar to the constitution of pristine dentin, showing that, within this fluence range, the laser treatment does not significantly modify the structure and constitution of dentin. The results achieved suggest an ablation mechanism where collagen is preferentially decomposed by the laser radiation, reducing the tissue cohesive strength and leading, ultimately, to its ablation.

Constitution of the Federal Republic of Nigeria (Promulgation) Decree 1989 (No. 12 of 1989).

PubMed

1989-01-01

This document contains major provisions of the Constitution of the Federal Republic of Nigeria which was promulgated by decree in 1989. The Constitution guarantees every citizen equality under the law. Opportunities to secure employment without discrimination are protected; working conditions are to be safe and humane; adequate medical and health facilities are to be available; pay equity is assured; vulnerable groups (children, the aged, and the disabled) are to receive social protection; and the free movement of citizens is assured. The third part of the constitution establishes a national population census which is to be submitted to the President of the country for acceptance.

From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry.

PubMed

Lehn, Jean-Marie

2007-02-01

Supramolecular chemistry has developed over the last forty years as chemistry beyond the molecule. Starting with the investigation of the basis of molecular recognition, it has explored the implementation of molecular information in the programming of chemical systems towards self-organisation processes, that may occur either on the basis of design or with selection of their components. Supramolecular entities are by nature constitutionally dynamic by virtue of the lability of non-covalent interactions. Importing such features into molecular chemistry, through the introduction of reversible bonds into molecules, leads to the emergence of a constitutional dynamic chemistry, covering both the molecular and supramolecular levels. It considers chemical objects and systems capable of responding to external solicitations by modification of their constitution through component exchange or reorganisation. It thus opens the way towards an adaptive and evolutive chemistry, a further step towards the chemistry of complex matter.

Small nucleolar RNAs that guide modification in trypanosomatids: repertoire, targets, genome organisation, and unique functions.

PubMed

Uliel, Shai; Liang, Xue-hai; Unger, Ron; Michaeli, Shulamit

2004-03-29

Small nucleolar RNAs constitute a family of newly discovered non-coding small RNAs, most of which function in guiding RNA modifications. Two prevalent types of modifications are 2'-O-methylation and pseudouridylation. The modification is directed by the formation of a canonical small nucleolar RNA-target duplex. Initially, RNA-guided modification was shown to take place on rRNA, but recent studies suggest that small nuclear RNA, mRNA, tRNA, and the trypanosome spliced leader RNA also undergo guided modifications. Trypanosomes contain more modifications and potentially more small nucleolar RNAs than yeast, and the increased number of modifications may help to preserve ribosome function under adverse environmental conditions during the cycling between the insect and mammalian host. The genome organisation in clusters carrying the two types of small nucleolar RNAs, C/D and H/ACA-like RNAs, resembles that in plants. However, the trypanosomatid H/ACA RNAs are similar to those found in Archaea and are composed of a single hairpin that may represent the primordial H/ACA RNA. In this review we summarise this new field of trypanosome small nucleolar RNAs, emphasising the open questions regarding the number of small nucleolar RNAs, the repertoire, genome organisation, and the unique function of guided modifications in these protozoan parasites.

Hydroelectrolytic and hormonal modifications related to prolonged bedrest in antiorthostatic position

NASA Astrophysics Data System (ADS)

Güell, A.; Dupui, Ph.; Fanjaud, G.; Bes, A.; Moatti, J. P.; Gharrib, Cl.

The effects of prolonged bedrest in antiorthostatic position (-4° head down) on electrolyte balance were studied in 4 young volunteers. An increase was noted in sodium excretion during the first 4 days. Plasma renin activity and plasma aldosterone varied in parallel manner during the same period. Potassium balance and creatinine clearance were not significantly modified. In light of these data we feel that prolonged bedrest in antiorthostatic position constitutes an effective way to simulate on earth metabolic and hormonal modifications occurring in man under weightlessness conditions.

Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development.

PubMed

Ikegami, Kohta; Ohgane, Jun; Tanaka, Satoshi; Yagi, Shintaro; Shiota, Kunio

2009-01-01

Genes constitute only a small proportion of the mammalian genome, the majority of which is composed of non-genic repetitive elements including interspersed repeats and satellites. A unique feature of the mammalian genome is that there are numerous tissue-dependent, differentially methylated regions (T-DMRs) in the non-repetitive sequences, which include genes and their regulatory elements. The epigenetic status of T-DMRs varies from that of repetitive elements and constitutes the DNA methylation profile genome-wide. Since the DNA methylation profile is specific to each cell and tissue type, much like a fingerprint, it can be used as a means of identification. The formation of DNA methylation profiles is the basis for cell differentiation and development in mammals. The epigenetic status of each T-DMR is regulated by the interplay between DNA methyltransferases, histone modification enzymes, histone subtypes, non-histone nuclear proteins and non-coding RNAs. In this review, we will discuss how these epigenetic factors cooperate to establish cell- and tissue-specific DNA methylation profiles.

ARSENIC REMOVAL FROM DRINKING WATER BY PROCESS MODIFICATION TO COAGULATION/FILTRATION. USEPA DEMONSTRATION PROJECT AT LIDGERWOOD, ND. FINAL PERFORMANCE EVALUATION REPORT

EPA Science Inventory

This report documents the activities performed and the results obtained for the arsenic removal treatment technology demonstration project at the Lidgerwood, North Dakota site. The objectives of the project were to evaluate: (1) the effectiveness of process modifications to an e...

We the Students: Supreme Court Cases for and about Students.

ERIC Educational Resources Information Center

Raskin, Jamin B.

This casebook intends to show young people that their rights, their way of life, and indeed sometimes their very life, can depend on one remarkable document, the Constitution of the United States. The casebook is about the United States Constitution and how the Supreme Court and lower courts have interpreted it to govern the lives of U.S. public…

Constitutional Issues: Separation of Powers. Teaching with Documents.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

The United States subscribes to the original premise of the framers of the Constitution that the way to safeguard against tyranny is to separate the powers of government among three branches so that each branch checks the other two. At no time in the 20th century was the devotion to that principle more vigorously evoked than in 1937, when…

Watergate: A Teaching Unit. Curriculum Project Report No. 4040. Experimental Edition.

ERIC Educational Resources Information Center

Malament, Elizabeth E.

Because Watergate tested the strength of the U.S. constitutional system and proved that it worked, this unit could serve as a focal point for study of the U.S. Constitution. The three objectives of the document are: (1) to expand knowledge of the governance process through study of the separation of powers, the impeachment process, the right to…

Can Embedded Annotations Help High School Students Perform Problem Solving Tasks Using a Web-Based Historical Document?

ERIC Educational Resources Information Center

Lee, John K.; Calandra, Brendan

2004-01-01

Two versions of a Web site on the United States Constitution were used by students in separate high school history classes to solve problems that emerged from four constitutional scenarios. One site contained embedded conceptual scaffolding devices in the form of textual annotations; the other did not. The results of our study demonstrated the…

Charters, Constitutions and By-Laws of the Indian Tribes of North America, Part VII: The Indian Tribes of California.

ERIC Educational Resources Information Center

Fay, George E., Comp.

The publication, Part VII of a series, includes the charters, constitutions, articles of association or community organization, and by-laws of California Indians on 16 reservations and rancherias. Legal documents from the following groups are provided: Hoopa, Me-Wuk, and Paiute Indians; the Agua Caliente Band of Mission Indians; the Mission Creek…

PSD Questions Associated with Proposed Modification at E.I. Du Pont De Nemours and Company's Spruance Plant

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Applicability of the PSD Regulations to Certain Modifications Made by Cooper Tire and Rubber Company

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Recommendation on Whether 112(g) Applies to a Proposed Modification at New Flyer USA in St. Cloud, MN

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Guidance on Major Modification Provisions of PSD Rules as Applied to Re-Permitting at Acme Steel Co.

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Proposed Netting for Modifications at Cyprus Northshore Mining Corporation, Silver Bay, Minnesota

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Order Responding to January 2, 2001 Petition for EPA to Object to Borden's Permit Modification

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Applicability of the PSD Regulations to a Modification at the Little America Refinery

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Petition for Administrator to Object to Permit Modification of Dow Chemicals, Inc. Permit

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Clarification That BACT Analysis Under PSD is Applicable for A Proposed Modification to the Rotary Kiln

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

29 CFR 801.71 - Filing and service.

Code of Federal Regulations, 2011 CFR

2011-07-01

... EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Modification Or Vacation of Decision... of time for delivery by mail. Documents are not deemed filed with the Secretary until actually... Secretary either on or before the due date. No additional time shall be added where service of a document...

29 CFR 801.71 - Filing and service.

Code of Federal Regulations, 2010 CFR

2010-07-01

... EMPLOYEE POLYGRAPH PROTECTION ACT OF 1988 Administrative Proceedings Modification Or Vacation of Decision... of time for delivery by mail. Documents are not deemed filed with the Secretary until actually... Secretary either on or before the due date. No additional time shall be added where service of a document...

Aviation System Analysis Capability Quick Response System Report for Fiscal Year 1998

NASA Technical Reports Server (NTRS)

Ege, Russell; Villani, James; Ritter, Paul

1999-01-01

This document presents the additions and modifications made to the Quick Response System (QRS) in FY 1998 in support of the ASAC QRS development effort. this Document builds upon the Aviation System Analysis Capability Quick Responses System Report for Fiscal Year 1997.

17 CFR 230.428 - Documents constituting a section 10(a) prospectus for Form S-8 registration statement...

Code of Federal Regulations, 2010 CFR

2010-04-01

... employee benefit plan information required by Item 1 of the Form; (ii) The statement of availability of registrant information, employee benefit plan annual reports and other information required by Item 2; and (iii) The documents containing registrant information and employee benefit plan annual reports that are...

76 FR 9491 - Delegation of Reporting and Other Authorities

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

...--Delegation of Reporting and Other Authorities #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 76, No. 33 / Thursday, February 17, 2011 / Presidential Documents#0;#0; #0; #0;Title 3-- #0... Constitution and the laws of the United States, including section 301 of title 3, United States Code, I hereby...

Documentos de consulta para iniciar la reforma educativa (Preparatory documents on educational reform).

ERIC Educational Resources Information Center

Consejo Nacional Tecnico de la Educacion (Mexico).

This document is an English-language abstract (approximately 1,500 words) of two booklets on Mexican educational reform. The first booklet cites the parts of the Mexican Constitution dealing with education, the legal foundation of Mexican education, stipulating that it shall be universal, democratic, national, compulsory, free and immune from…

3 CFR - Delegation of Reporting and Other Authorities

Code of Federal Regulations, 2012 CFR

2012-01-01

... 3 The President 1 2012-01-01 2012-01-01 false Delegation of Reporting and Other Authorities Presidential Documents Other Presidential Documents Memorandum of February 14, 2011 Delegation of Reporting and Other Authorities Memorandum for the Secretary of Agriculture By the authority vested in me as President by the Constitution and the laws of th...

3 CFR - Unexpected Urgent Refugee and Migration Needs

Code of Federal Regulations, 2013 CFR

2013-01-01

... 3 The President 1 2013-01-01 2013-01-01 false Unexpected Urgent Refugee and Migration Needs Presidential Documents Other Presidential Documents Presidential Determination No. 2012-6 of April 3, 2012 Unexpected Urgent Refugee and Migration Needs Memorandum for the Secretary of State By the authority vested in me as President by the Constitution...

3 CFR - Delegation of a Reporting Authority

Code of Federal Regulations, 2014 CFR

2014-01-01

... 3 The President 1 2014-01-01 2014-01-01 false Delegation of a Reporting Authority Presidential Documents Other Presidential Documents Memorandum of January 31, 2013 Delegation of a Reporting Authority Memorandum for the Secretary of Transportation By the authority vested in me as President by the Constitution and the laws of the United States,...

3 CFR - Delegation of a Reporting Authority

Code of Federal Regulations, 2011 CFR

2011-01-01

... 3 The President 1 2011-01-01 2011-01-01 false Delegation of a Reporting Authority Presidential Documents Other Presidential Documents Memorandum of April 7, 2010 Delegation of a Reporting Authority Memorandum for the Secretary of State By the authority vested in me as President by the Constitution and the laws of the United States, including...

Double Mapping in Metaphorical Expressions of Thought and Communication in Catalan Sign Language (LSC)

ERIC Educational Resources Information Center

Jarque, Maria-Josep

2005-01-01

This document illustrates that mental functioning and communication in Catalan Sign Language (LSC) are conceptual through metaphorical projection of bodily experiences. The data in this document show how concepts are grasped, put on student's heads, exchanged, manipulated, and so on, constituting instantiations of the basic metaphors: ideas are…

Addendum to the Closure Report for Corrective Action Unit 165: Area 25 and 26 Dry Well and Washdown Areas, Nevada Test Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krauss, Mark J

This document constitutes an addendum to the Closure Report for Corrective Action Unit 165: Area 25 and 26 Dry Well and Washdown Areas, Nevada Test Site, Nevada as described in the document Recommendations and Justifications To Remove Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order dated September 2013. The Use Restriction Removal document was approved by the Nevada Division of Environmental Protection on October 16, 2013. The approval of the UR Removal document constituted approval of each of the recommended UR removals. In conformance with themore » UR Removal document, this addendum consists of: This page that refers the reader to the UR Removal document for additional information The cover, title, and signature pages of the UR Removal document The NDEP approval letter The corresponding section of the UR Removal document This addendum provides the documentation justifying the cancellation of the UR for CAS 25-20-01, Lab Drain Dry Well. This UR was established as part of FFACO corrective actions and was based on the presence of tetrachloroethene contamination at concentrations greater than the action level established at the time of the initial investigation. Although total petroleum hydrocarbon diesel-range organics contamination at concentrations greater than the NDEP action level was present at the site, no hazardous constituents of TPH-DRO exceeded the U.S. Environmental Protection Agency (EPA) Region 9 preliminary remediation goals established at the time of the initial investigation.« less

25 CFR 81.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... AFFAIRS, DEPARTMENT OF THE INTERIOR TRIBAL GOVERNMENT TRIBAL REORGANIZATION UNDER A FEDERAL STATUTE § 81.1... section who has attained the age of 18 years. (b) Amendment means any modification, change, or total revision of a constitution or charter. (c) Authorizing Officer means the Bureau of Indian Affairs official...

Aviation System Analysis Capability Quick Response System Report

NASA Technical Reports Server (NTRS)

Roberts, Eileen; Villani, James A.; Ritter, Paul

1998-01-01

The purpose of this document is to present the additions and modifications made to the Aviation System Analysis Capability (ASAC) Quick Response System (QRS) in FY 1997 in support of the ASAC ORS development effort. This document contains an overview of the project background and scope and defines the QRS. The document also presents an overview of the Logistics Management Institute (LMI) facility that supports the QRS, and it includes a summary of the planned additions to the QRS in FY 1998. The document has five appendices.

NLS Flight Simulation Laboratory (FSL) documentation

NASA Technical Reports Server (NTRS)

1995-01-01

The Flight Simulation Laboratory (FSL) Electronic Documentation System design consists of modification and utilization of the MSFC Integrated Engineering System (IES), translation of the existing FSL documentation to an electronic format, and generation of new drawings to represent the Engine Flight Simulation Laboratory design and implementation. The intent of the electronic documentation is to provide ease of access, local print/plot capabilities, as well as the ability to correct and/or modify the stored data by network users who are authorized to access this information.

How Posttranslational Modification of Nitrogenase Is Circumvented in Rhodopseudomonas palustris Strains That Produce Hydrogen Gas Constitutively

PubMed Central

Heiniger, Erin K.; Oda, Yasuhiro; Samanta, Sudip K.

2012-01-01

Nitrogenase catalyzes the conversion of dinitrogen gas (N2) and protons to ammonia and hydrogen gas (H2). This is a catalytically difficult reaction that requires large amounts of ATP and reducing power. Thus, nitrogenase is not normally expressed or active in bacteria grown with a readily utilized nitrogen source like ammonium. nifA* mutants of the purple nonsulfur phototrophic bacterium Rhodopseudomonas palustris have been described that express nitrogenase genes constitutively and produce H2 when grown with ammonium as a nitrogen source. This raised the regulatory paradox of why these mutants are apparently resistant to a known posttranslational modification system that should switch off the activity of nitrogenase. Microarray, mutation analysis, and gene expression studies showed that posttranslational regulation of nitrogenase activity in R. palustris depends on two proteins: DraT2, an ADP-ribosyltransferase, and GlnK2, an NtrC-regulated PII protein. GlnK2 was not well expressed in ammonium-grown NifA* cells and thus not available to activate the DraT2 nitrogenase modification enzyme. In addition, the NifA* strain had elevated nitrogenase activity due to overexpression of the nif genes, and this increased amount of expression overwhelmed a basal level of activity of DraT2 in ammonium-grown cells. Thus, insufficient levels of both GlnK2 and DraT2 allow H2 production by an nifA* mutant grown with ammonium. Inactivation of the nitrogenase posttranslational modification system by mutation of draT2 resulted in increased H2 production by ammonium-grown NifA* cells. PMID:22179236

Identification, modification, and implementation of an evidence-based psychotherapy for children in a low-income country: the use of TF-CBT in Zambia

PubMed Central

2013-01-01

Background The need to address the treatment gap in mental health services in low- and middle-income countries (LMIC) is well recognized and particularly neglected among children and adolescents. Recent literature with adult populations suggests that evidence-based mental health treatments are effective, feasible, and cross-culturally modifiable for use in LMIC. This paper addresses a gap in the literature documenting pre-trial processes. We describe the process of selecting an intervention to meet the needs of a particular population and the process of cross-cultural adaptation. Methods Community-based participatory research principles were implemented for intervention selection, including joint meetings with stakeholders, review of qualitative research, and review of the literature. Trauma-focused Cognitive Behavioral Therapy (TF-CBT) was chosen as the evidence-based practice for modification and feasibility testing. The TF-CBT adaptation process, rooted within an apprenticeship model of training and supervision, is presented. Clinical case notes were reviewed to document modifications. Results Choosing an intervention can work as a collaborative process with community involvement. Results also show that modifications were focused primarily on implementation techniques rather than changes in TF-CBT core elements. Conclusions Studies documenting implementation processes are critical to understanding why intervention choices are made and how the adaptations are generated in global mental health. More articles are needed on how to implement evidence-based treatments in LMIC. PMID:24148551

Alvarado Flood Risk Management Modifications to Existing Project Section 408 Review. Review Plan

DTIC Science & Technology

2012-12-26

Digital Flood Insurance Rate Maps) through the Nationa l Flood Insurance Program ( NFIP ). In order to obtain FEMA accreditation, the levee owner...compliance documentation for meeting NFIP requirements. Barr conducted a thorough review of relevant documents to gain a better understanding of...compliance documentation for meeting NFIP requirements. Barr Engineering has prepared a Phase I Engineer’s Report and is developing plans and

General Astrophysics and Comparative Planetology with the Terrestrial Planet Finder Missions

NASA Technical Reports Server (NTRS)

Kuchner, Marc J. (Editor)

2005-01-01

This document discusses the potential of the Terrestrial Planet Finder (TPF) for general astrophysics beyond its base mission, focusing on science obtainable with no or minimal modifications to the mission design, but also exploring possible modifications of TPF with high scientific merit and no impact on the basic search for extrasolar Earth analogs.

43 CFR Appendix III to Part 11 - Format for Data Inputs and Modifications to the NRDAM/GLE

Code of Federal Regulations, 2012 CFR

2012-10-01

... area represented by its geographic database. Any water within the geographic boundaries of the NRDAM... U.S. Department of Commerce/Bureau of Economic Analysis, 1441 L Street, NW, Washington, D.C., 20230, (202) 606-9900.] Modifications to the NRDAM/GLE Databases (if Any) Documentation of the source of the...

43 CFR Appendix III to Part 11 - Format for Data Inputs and Modifications to the NRDAM/GLE

Code of Federal Regulations, 2011 CFR

2011-10-01

... area represented by its geographic database. Any water within the geographic boundaries of the NRDAM... U.S. Department of Commerce/Bureau of Economic Analysis, 1441 L Street, NW, Washington, D.C., 20230, (202) 606-9900.] Modifications to the NRDAM/GLE Databases (if Any) Documentation of the source of the...

43 CFR Appendix III to Part 11 - Format for Data Inputs and Modifications to the NRDAM/GLE

Code of Federal Regulations, 2014 CFR

2014-10-01

... area represented by its geographic database. Any water within the geographic boundaries of the NRDAM... U.S. Department of Commerce/Bureau of Economic Analysis, 1441 L Street, NW, Washington, D.C., 20230, (202) 606-9900.] Modifications to the NRDAM/GLE Databases (if Any) Documentation of the source of the...

43 CFR Appendix III to Part 11 - Format for Data Inputs and Modifications to the NRDAM/GLE

Code of Federal Regulations, 2013 CFR

2013-10-01

... area represented by its geographic database. Any water within the geographic boundaries of the NRDAM... U.S. Department of Commerce/Bureau of Economic Analysis, 1441 L Street, NW, Washington, D.C., 20230, (202) 606-9900.] Modifications to the NRDAM/GLE Databases (if Any) Documentation of the source of the...

75 FR 15609 - Certification of Aircraft and Airmen for the Operation of Light-Sport Aircraft; Modifications to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

...- Sport Aircraft; Modifications to Rules for Sport Pilots and Flight Instructors With a Sport Pilot Rating... regulations for sport pilots and flight instructors with a sport pilot rating to address airman certification... for the operation of light-sport aircraft were implemented in 2004. This document corrects errors in...

Retrofit and acceptance test of 30-cm ion thrusters

NASA Technical Reports Server (NTRS)

Poeschel, R. L.

1981-01-01

Six 30 cm mercury thrusters were modified to the J-series design and evaluated using standardized test procedures. The thruster performance meets the design objectives (lifetime objective requires verification), and documentation (drawings, etc.) for the design is completed and upgraded. The retrofit modifications are described and the test data for the modifications are presented and discussed.

The use of NUREGs 1199 and 1200 in the Illinois LLW licensing program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klinger, J.G.; Harmon, D.F.

1991-12-31

This paper will describe how the LLW licensing staff of the Illinois Department of Nuclear Safety used NRC`s NUREG 1199, NUREG 1200, NUREG 1300 and Regulatory Guide 4.18 in its licensing program for reviewing and evaluating a LLW disposal facility license application. The paper will discuss how Illinois guidance documents were prepared based on modifications made to these NRC documents which were necessary to take into account site and facility specific considerations, as well as changes required by Illinois statutes and regulatory codes. The paper will review the recent revisions (January 1991) to NUREG 1199 and 1200 and the importancemore » of these revisions. The paper will also discuss recommended modifications to these NRC documents and provide an update on the status of the Department`s review and evaluation of an application for a license to site, construct and operate a LLW disposal facility in Illinois.« less

Constitutions and Democratic Consolidation: Brazil in Comparative Perspective

DTIC Science & Technology

1989-03-31

FIED i(CURIty CLASSIFICATION 0$ T64 S PAGE REPORT DOCUMENTATION PAGE la REPORT SECURITY CLASSIFICATION lb RESTRICTIVE MARKINGS UNCLASSI FIED la SECURITY...majority. The members sought to guarantee the revolutionary changes and continue them into the future by inclusion in the Constitution. Instead...Bresser Pereira, "Economic Ideologies and Democracy in Brazil," paper presented to seminar on L’Internationalisation de la Democratie Politique

The First Page of the Official Journal of the Constitutional Convention--Just the Tip of a Records Iceberg!

ERIC Educational Resources Information Center

Potter, Lee Ann

2012-01-01

On Monday, September 17, 1787, 39 delegates to the Federal Convention in Philadelphia signed the Constitution of the United States, along with Major William Jackson, who had served as the secretary of the Convention. That same day, Jackson received instructions to leave for New York City on Tuesday and carry the document to Congress. All of these…

2010-11 NCAA[R] Division II Manual

ERIC Educational Resources Information Center

National Collegiate Athletic Association (NJ1), 2010

2010-01-01

This publication incorporates the final legislative actions of the 104th annual NCAA Convention, January 13-16, 2010. In addition, interpretations incorporated by the Legislative Review Subcommittee, noncontroversial amendments adopted by the Management Council, pursuant to Constitution 5.3.1.1.1, and modifications of wording adopted by the…

Behavioral Treatment and Normal Educational and Intellectual Functioning in Young Autistic Children.

ERIC Educational Resources Information Center

Lovaas, O. Ivar

1987-01-01

Reports the results of behavior modification treatment for two groups of similarly constituted, young autistic children. Pretreatment measures revealed no significant differences between the intensively treated experimental group and the minimally treated control groups. At follow-up, experimental group subjects (N=19) did significantly better…

75 FR 43825 - Exemption to Prohibition on Circumvention of Copyright Protection Systems for Access Control...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

... works such as video games and slide presentations). B. Computer programs that enable wireless telephone... enabling interoperability of such applications, when they have been lawfully obtained, with computer... new printer driver to a computer constitutes a `modification' of the operating system already...

18 CFR 376.209 - Procedures during periods of emergency requiring activation of the Continuity of Operations Plan.

Code of Federal Regulations, 2010 CFR

2010-04-01

... activated during emergency conditions lasting up to 30 days during which Commission headquarters operations may be temporarily disrupted or communications with the Commission's headquarters may be temporarily... Commission's headquarters constituted, and appropriate modifications made to the alternative Web site. (2...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

These case studies constitute Part II of the ACL Guidance Document. They are intended to assist Regional and State personnel in exercising the discretion conferred by regulation in evaluating applications for alternate concentration limits (ACLs) submitted pursuant to 40 CFR 264.94. The document is not a regulation and should not be used as such. Regional and State personnel must exercise their discretion in using this guidance document as well as other relevant information in determining whether an ACL demonstration meets the regulatory standard.

Exploring the Legacy of Magna Carta with Students through Historic Images

ERIC Educational Resources Information Center

Wesson, Stephen

2014-01-01

Every iconic document owes a debt to a document that came before it, just as its creators were influenced by the thinkers and writers who came before them. The Declaration of Independence, U.S. Constitution, and Bill of Rights were revolutionary works, and have become powerful symbols of democracy worldwide. Behind them stands an even older…

Computer program and user documentation medical data tape retrieval system

NASA Technical Reports Server (NTRS)

Anderson, J.

1971-01-01

This volume provides several levels of documentation for the program module of the NASA medical directorate mini-computer storage and retrieval system. A biomedical information system overview describes some of the reasons for the development of the mini-computer storage and retrieval system. It briefly outlines all of the program modules which constitute the system.

11 CFR 9409.5 - Procedures for demand for testimony or production of documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 11 Federal Elections 1 2010-01-01 2010-01-01 false Procedures for demand for testimony or... § 9409.5 Procedures for demand for testimony or production of documents. (a) A demand directed to the... New York Avenue, NW., Suite 1100, Washington, DC 20005. Acceptance of a demand shall not constitute an...

Guidance on Major Modification Provisions of PSD Rules as Applied to Re-Permitting at Acme Steel Co.

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Response to Inquiry Regarding Routine Maintenance, Repair and Replacement Analysis for Recovery Furnace Modifications at Longview Fibre, Longview Mill and Boise Cascade Corporation, Wallula Mill

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Order Responding to June 18, 2001 Petition for the Admininstrator to Object to Significant Permit Modification to Dow Chemical Company's Operating Permit

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Petition Database available at www2.epa.gov/title-v-operating-permits/title-v-petition-database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Follow up on Request for EPA's Headquarters to Review Region V's Previous Determination that the Proposed Fuel Conversion was a Major Modification for PSD Purposes

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

North Carolina's Implementation of Visibility Impact Assessment Requirements for New Major Stationary Sources and Major Modifications Subject to Clean Air Act Prevention of Significant Deterioration Requirements

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Jets in Heavy Ion Collisions with the ATLAS Detector

NASA Astrophysics Data System (ADS)

Santos, Helena

Jets constitute a golden probe to study the quark gluon plasma produced in heavy ion collisions at the LHC. Being produced at the early stages of the collisions, they are expected to be modified as propagating through the hot and dense medium. A signature of the modification is the energy loss lowering the jet yields at a given transverse momentum. A factor of two suppression is observed in central Pb+Pb collisions with respect to pp collisions. Other signatures are the modification of the dijet momentum balance and the modification of fragmentation functions. These proceedings describe results on these observables from ATLAS in Runs 1 and 2. The high statistical significance of these data samples collected by ATLAS allows precision measurements of these observables in a wide range of transverse momentum and centrality.

GRC-11-02-17-WindTunnel-9x15-001

NASA Image and Video Library

2017-11-02

The Aerosciences Evaluation and Test Capabilities (AETC) Portfolio implemented the Capability Challenge to “Reduce Background Noise Levels for Engine Efficiency Measurements at the NASA Glenn 9x15 Low Speed Wind Tunnel”. The 9x15 Low Speed Wind Tunnel Acoustic Improvements animation documents the acoustic modifications being made to the 9x15 leg of the wind tunnel to reduce background noise levels. A brief history of the 9x15, research testing performed in the wind tunnel, the need to reduce background noise, and the five state of the art acoustic design modifications are documented in the animation. The expected noise reduction is presented audibly and the resulting benefit to NASA is also defined.

76 FR 44935 - Draft Guidance for Industry and Food and Drug Administration Staff; 510(k) Device Modifications...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-27

.... In August 2010, the Center for Devices and Radiological Health (CDRH) published two documents in.... These documents are titled ``CDRH Preliminary Internal Evaluations--Volume I: 510(k) Working Group Preliminary Report and Recommendations'' and ``CDRH Preliminary Internal Evaluations--Volume II: Task Force on...

ROMPS critical design review. Volume 2: Robot module design documentation

NASA Technical Reports Server (NTRS)

Dobbs, M. E.

1992-01-01

The robot module design documentation for the Remote Operated Materials Processing in Space (ROMPS) experiment is compiled. This volume presents the following information: robot module modifications; Easylab commands definitions and flowcharts; Easylab program definitions and flowcharts; robot module fault conditions and structure charts; and C-DOC flow structure and cross references.

The rational parameterization theorem for multisite post-translational modification systems.

PubMed

Thomson, Matthew; Gunawardena, Jeremy

2009-12-21

Post-translational modification of proteins plays a central role in cellular regulation but its study has been hampered by the exponential increase in substrate modification forms ("modforms") with increasing numbers of sites. We consider here biochemical networks arising from post-translational modification under mass-action kinetics, allowing for multiple substrates, having different types of modification (phosphorylation, methylation, acetylation, etc.) on multiple sites, acted upon by multiple forward and reverse enzymes (in total number L), using general enzymatic mechanisms. These assumptions are substantially more general than in previous studies. We show that the steady-state modform concentrations constitute an algebraic variety that can be parameterized by rational functions of the L free enzyme concentrations, with coefficients which are rational functions of the rate constants. The parameterization allows steady states to be calculated by solving L algebraic equations, a dramatic reduction compared to simulating an exponentially large number of differential equations. This complexity collapse enables analysis in contexts that were previously intractable and leads to biological predictions that we review. Our results lay a foundation for the systems biology of post-translational modification and suggest deeper connections between biochemical networks and algebraic geometry.

The Use of Lifestyle and Behavioral Modification Approaches in Obesity Interventions for Black Women: A Literature Review

ERIC Educational Resources Information Center

Walker, Renee E.; Gordon, Melanie

2014-01-01

The alarming obesity prevalence in Black women is well documented yet poorly understood. Obesity interventions for Black women have failed to produce long-term reductions in weight. Recommendations to incorporate a lifestyle and behavioral modification approach have been made to address obesity in this population. The purpose of this article was…

Application Reuse Library for Software, Requirements, and Guidelines

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Thronesbery, Carroll

1994-01-01

Better designs are needed for expert systems and other operations automation software, for more reliable, usable and effective human support. A prototype computer-aided Application Reuse Library shows feasibility of supporting concurrent development and improvement of advanced software by users, analysts, software developers, and human-computer interaction experts. Such a library expedites development of quality software, by providing working, documented examples, which support understanding, modification and reuse of requirements as well as code. It explicitly documents and implicitly embodies design guidelines, standards and conventions. The Application Reuse Library provides application modules with Demo-and-Tester elements. Developers and users can evaluate applicability of a library module and test modifications, by running it interactively. Sub-modules provide application code and displays and controls. The library supports software modification and reuse, by providing alternative versions of application and display functionality. Information about human support and display requirements is provided, so that modifications will conform to guidelines. The library supports entry of new application modules from developers throughout an organization. Example library modules include a timer, some buttons and special fonts, and a real-time data interface program. The library prototype is implemented in the object-oriented G2 environment for developing real-time expert systems.

Aircraft modifications: Assessing the current state of Air Force aircraft modifications and the implications for future military capability

NASA Astrophysics Data System (ADS)

Hill, Owen Jacob

How prepared is the U.S. Air Force to modify its aircraft fleet in upcoming years? Aircraft modernization is a complex interaction of new and legacy aircraft, organizational structure, and planning policy. This research will take one component of modernization: aircraft modification, and apply a new method of analysis in order to help formulate policy to promote modernization. Departing from previous small-sample studies dependent upon weight as a chief explanatory variable, this dissertation incorporates a comprehensive dataset that was constructed for this research of all aircraft modifications from 1996 through 2005. With over 700 modification programs, this dataset is used to examine changes to the current modification policy using policy-response regression models. These changes include separating a codependent procurement and installation schedule, reducing the documentation requirements for safety modifications, and budgeting for aging aircraft modifications. The research then concludes with predictive models for the F-15 and F-16 along with their replacements: the F-22 and F-35 Joint Strike Fighter.

Chemical methods for encoding and decoding of posttranslational modifications

PubMed Central

Chuh, Kelly N.; Batt, Anna R.; Pratt, Matthew R.

2016-01-01

A large array of posttranslational modifications can dramatically change the properties of proteins and influence different aspects of their biological function such as enzymatic activity, binding interactions, and proteostasis. Despite the significant knowledge that has been gained about the function of posttranslational modifications using traditional biological techniques, the analysis of the site-specific effects of a particular modification, the identification of the full compliment of modified proteins in the proteome, and the detection of new types of modifications remains challenging. Over the years, chemical methods have contributed significantly in both of these areas of research. This review highlights several posttranslational modifications where chemistry-based approaches have made significant contributions to our ability to both prepare homogeneously modified proteins and identify and characterize particular modifications in complex biological settings. As the number and chemical diversity of documented posttranslational modifications continues to rise, we believe that chemical strategies will be essential to advance the field in years to come. PMID:26933738

Draft of the U.S. Constitution (August 1787) and Schedule of the Compensation of the Senate of the United States (March 1791)

ERIC Educational Resources Information Center

Hussey, Michael; Greenhut, Stephanie

2011-01-01

This article features two documents which can serve as a starting point for a lesson on public service while students debate the amount of pay that public servants should receive. These are: (1) the printed draft of the Constitution showing George Washington's handwritten corrections that eliminated state payments and included the phrase "to be…

"United States v. Thomas Cooper": A Violation of the Sedition Law. The Constitution Community: Revolution and the New Nation (1754-1820s).

ERIC Educational Resources Information Center

Lawlor, John M., Jr.

This lesson relates to freedom of speech and freedom of the press as provided for in the First Amendment of the U.S. Constitution. The lesson correlates to the National History Standards and the National Standards for Civics and Government. It presents seven primary source documents regarding Thomas Cooper's trial for sedition in 1800. Cooper was…

[Recommendations for the control of documents and the establishment of a documentary system].

PubMed

Vinner, E

2013-06-01

The quality management system that must be implemented in a MBL to meet the requirements of the standard NF EN ISO 15189 is based, among other things, on the creation and use by staff of a documentary system approved and updated. This documentary system is constituted by external documents (standards, suppliers' documents...) and internal documents (quality manual, procedures, instructions, technical and quality recordings...). A procedure of the documentary system control must be formalized. The documentary system should be modeled in order to identify the various procedures to be drafted and the incurred risks in the case a document would be missing in this system. Each document must be indexed in a unique way and document management must be carried out rigorously. The use of document management software is a great help to manage the life cycle of documents.

Alternative Significant Contribution Approaches Evaluated

EPA Pesticide Factsheets

This Technical Support Document (TSD) discusses alternative approaches that EPA evaluated for defining emissions that constitute each upwind state’s significant contribution to nonattainment and interference with maintenance downwind.

Humidity effects on soluble core mechanical and thermal properties (polyvinyl alcohol/microballoon composite) type CG extendospheres, volume 2

NASA Technical Reports Server (NTRS)

1993-01-01

This document constitutes the final report for the study of humidity effects and loading rate on soluble core (PVA/MB composite material) mechanical and thermal properties under Contract No. 100345. This report describes test results procedures employed, and any unusual occurrences or specific observations associated with this test program. The primary objective of this work was to determine if cured soluble core filler material regains its tensile and compressive strength after exposure to high humidity conditions and following a drying cycle. Secondary objectives include measurements of tensile and compressive modulus, and Poisson's ratio, and coefficient of thermal expansion (CTE) for various moisture exposure states. A third objective was to compare the mechanical and thermal properties of the composite using 'SG' and 'CG' type extendospheres. The proposed facility for the manufacture of soluble cores at the Yellow Creek site incorporates no capability for the control of humidity. Recent physical property tests performed with the soluble core filler material showed that prolonged exposure to high humidity significantly degradates in strength. The purpose of these tests is to determine if the product, process or facility designs require modification to avoid imparting a high risk condition to the ASRM.

Plasmin on adherent cells: from microvesiculation to apoptosis

PubMed Central

Doeuvre, Loïc; Plawinski, Laurent; Goux, Didier; Vivien, Denis; Anglés-Cano, Eduardo

2010-01-01

SYNOPSIS Cell activation by stressors is characterised by a sequence of detectable phenotypic cell changes. The strength of a given stimulus induces modifications in the activity of membrane phospholipids transporters and calpains, which leads to phosphatidylserine exposure, membrane blebbing and the release of microparticles (nanoscale membrane vesicles). This vesiculation could be considered as a warning signal that may be followed, if the stimulus is maintained, by cell detachment-induced apoptosis. In this study, plasminogen incubated onto adherent cells is activated into plasmin by constitutively expressed tPA or uPA. Plasmin formed on the cellular membrane then induces an unique response characterized by membrane blebbing and vesiculation. Hitherto unknown for plasmin, these membrane changes are similar to those induced by thrombin on platelets. If plasmin formation evolves, matrix proteins are then degraded, cells lose attachment and enter the apoptotic process, characterized by DNA fragmentation and electron microscopy features. This sequence of events was experimentally documented at all these stages. Since other proteolytic or inflammatory stimuli may evoke similar responses by distinct adherent cells, this sequence can be applied to distinguish activated adherent cells from cells entering the apoptotic process. This is a major definition crucial to the identification of mediators, inhibitors and potential therapeutic agents. PMID:20846121

Design review report for rotary mode core sample truck (RMCST) modifications for flammable gas tanks, preliminary design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Corbett, J.E.

1996-02-01

This report documents the completion of a preliminary design review for the Rotary Mode Core Sample Truck (RMCST) modifications for flammable gas tanks. The RMCST modifications are intended to support core sampling operations in waste tanks requiring flammable gas controls. The objective of this review was to validate basic design assumptions and concepts to support a path forward leading to a final design. The conclusion reached by the review committee was that the design was acceptable and efforts should continue toward a final design review.

3 CFR - Delegation of Authority Under Section 506(a)(1) of the Foreign Assistance Act of 1961, as Amended

Code of Federal Regulations, 2014 CFR

2014-01-01

... 3 The President 1 2014-01-01 2014-01-01 false Delegation of Authority Under Section 506(a)(1) of the Foreign Assistance Act of 1961, as Amended Presidential Documents Other Presidential Documents... by the Constitution and the laws of the United States of America, including section 301 of title 3...

3 CFR - Delegation of Functions Under Sections 1261(b) and 1262(a) of Public Law 112-239

Code of Federal Regulations, 2014 CFR

2014-01-01

... 3 The President 1 2014-01-01 2014-01-01 false Delegation of Functions Under Sections 1261(b) and 1262(a) of Public Law 112-239 Presidential Documents Other Presidential Documents Memorandum of October... by the Constitution and the laws of the United States, including section 301 of title 3, United...

"Records of Rights": A New Exhibit at the National Archives in Washington, D.C.

ERIC Educational Resources Information Center

Hussey, Michael

2014-01-01

America's founding documents--the Declaration of Independence, the Constitution, and the Bill of Rights--are icons of human liberty. But the ideals enshrined in those documents did not initially apply to all Americans. They were, in the words of Martin Luther King, Jr., "a promissory note to which every American was to fall heir."…

Think before You Shoot: The Relationship between Cognition and Marksmanship

DTIC Science & Technology

2011-09-01

be expedited if placed through the librarian or other person designated to request documents from DTIC. Change of address Organizations...position, policy, or decision, unless so designated by other official documentation. Citation of trade names in this report does not constitute an...cognitive impairments may require additional marksmanship training and re-learning prior to reintegration. cognition, marksmanship UNCLAS UNCLAS UNCLAS SAR

78 FR 42516 - Iroquois Gas Transmission System, L.P.; Notice of Intent To Prepare an Environmental Impact...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-16

... Public Scoping Meetings. At that time, Constitution proposed to construct a new compressor station as... has since identified that the objectives of the new compressor station could be met by making modifications at Iroquois' existing Wright Compressor Station in Schoharie County, New York. The other aspects...

Microprocessors: An Understandable Guide for the Classroom Teacher.

ERIC Educational Resources Information Center

Okinaka, Russell T.

A microprocessor constitutes the heart and soul of a personal computer. Indeed, the quality of a personal computer is determined largely by the type of microprocessor that is included within its circuitry. Since the microcomputer revolution began in the late 1970s, these special chips have gone through a series of improvements and modifications.…

7 CFR 1755.704 - Requirements applicable to both CCSR and NMR aerial service wires.

Code of Federal Regulations, 2011 CFR

2011-01-01

... service wires. 1755.704 Section 1755.704 Agriculture Regulations of the Department of Agriculture... aerial service wires. (a) Acceptance testing. (1) The tests described in §§ 1755.700 through 1755.704 are intended for acceptance of wire designs and major modifications of accepted designs. What constitutes a...

7 CFR 1755.704 - Requirements applicable to both CCSR and NMR aerial service wires.

Code of Federal Regulations, 2010 CFR

2010-01-01

... service wires. 1755.704 Section 1755.704 Agriculture Regulations of the Department of Agriculture... aerial service wires. (a) Acceptance testing. (1) The tests described in §§ 1755.700 through 1755.704 are intended for acceptance of wire designs and major modifications of accepted designs. What constitutes a...

Fuels and chemicals from equine-waste-derived tail gas reactive pyrolysis oil: technoeconomic analysis, environmental and exergetic life cycle assessment

USDA-ARS?s Scientific Manuscript database

Horse manure, whose improper disposal imposes considerable environmental costs, constitutes an apt feedstock for conversion to renewable fuels and chemicals when tail gas reactive pyrolysis (TGRP) is employed. TGRP is a modification of fast pyrolysis that recycles its non-condensable gases and produ...

Modifications to the Vulnerability Model: A Simulation System for Assessing Damage Resulting from Marine Spills

DTIC Science & Technology

1979-03-01

and they do not constituto a standard, specific-3tion, or regulation. This report, or portions thereof may not be used for advertising or sales ... promotion purposes. Citation of trade names and manufacturers does not constitute endorsement or approval of such products. I; Technical Report

Genetic and epigenetic alteration of the NF2 gene in sporadic meningiomas.

PubMed

Lomas, Jesus; Bello, M Josefa; Arjona, Dolores; Alonso, M Eva; Martinez-Glez, Victor; Lopez-Marin, Isabel; Amiñoso, Cinthia; de Campos, Jose M; Isla, Alberto; Vaquero, Jesus; Rey, Juan A

2005-03-01

The role of the NF2 gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2-associated tumors. Although epigenetic inactivation through aberrant CpG island methylation of the NF2 5' flanking region has been documented in schwannoma (another NF2-associated neoplasm), data on participation of this epigenetic modification in meningiomas are not yet widely available. Using methylation-specific PCR (MSP) plus sequencing, we assessed the presence of aberrant promoter NF2 methylation in a series of 88 meningiomas (61 grade I, 24 grade II, and 3 grade III), in which the allelic constitution at 22q and the NF2 mutational status also were determined by RFLP/microsatellite and PCR-SSCP analyses. Chromosome 22 allelic loss, NF2 gene mutation, and aberrant NF2 promoter methylation were detected in 49%, 24%, and 26% of cases, respectively. Aberrant NF2 methylation with loss of heterozygosity (LOH) at 22q was found in five cases, and aberrant methylation with NF2 mutation in another; LOH 22q and the mutation were found in 16 samples. The aberrant methylation of the NF2 gene also was the sole alteration in 15 samples, most of which were from grade I tumors. These results indicate that aberrant NF2 hypermethylation may participate in the development of a significant proportion of sporadic meningiomas, primarily those of grade I.

Diagnostic and therapeutic management of eosinophilic oesophagitis in children and adults: results from a Spanish registry of clinical practice.

PubMed

Lucendo, Alfredo J; Arias, Ángel; Molina-Infante, Javier; Rodríguez-Sánchez, Joaquín; Rodrigo, Luis; Nantes, Óscar; Pérez-Arellano, Elena; de la Riva, Susana; Pérez-Aisa, Ángeles; Barrio, Jesús

2013-07-01

Eosinophilic oesophagitis has emerged as a common cause of oesophageal symptoms. To document practice variation in care provided to eosinophilic oesophagitis patients in Spain and to assess adherence to available guidelines. A prospective survey-based registry including data from all patients receiving care from gastroenterologists and allergists throughout Spain was developed. Data from 705 patients (82% adults, male:female ratio 4.1:1) were collected from 26 Spanish hospitals. 42.7% received care in teaching hospitals. Adults presented dysphagia and food impaction more frequently; vomiting and weight loss predominated in children (p < 0.01). A mean diagnostic delay of 54.7 and 28.04 months was documented for adults and children, respectively. Normal endoscopic exams were reported in 27.6% and directly related to the experience in managing the disease (p < 0.05). Paediatric patients, non-teaching hospitals and greater experience in managing eosinophilic oesophagitis were associated with increased frequency in eosinophil count reports and with taking gastric and duodenal biopsies (p < 0.001). Initial therapy consisted of topical steroids (61.7% of patients), proton pump inhibitors (52.4%), dietary modifications (51.26%) and endoscopic dilation (7.2%). Referrals to allergy units occurred more frequently in teaching hospitals (p = 0.003) where food restrictions generally followed allergy test results (p < 0.001). Availability of facilities and the physician's experience constituted the most important factors in explaining differences in patient management. Copyright © 2013 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Application of histone modification-specific interaction domains as an alternative to antibodies.

PubMed

Kungulovski, Goran; Kycia, Ina; Tamas, Raluca; Jurkowska, Renata Z; Kudithipudi, Srikanth; Henry, Chisato; Reinhardt, Richard; Labhart, Paul; Jeltsch, Albert

2014-11-01

Post-translational modifications (PTMs) of histones constitute a major chromatin indexing mechanism, and their proper characterization is of highest biological importance. So far, PTM-specific antibodies have been the standard reagent for studying histone PTMs despite caveats such as lot-to-lot variability of specificity and binding affinity. Herein, we successfully employed naturally occurring and engineered histone modification interacting domains for detection and identification of histone PTMs and ChIP-like enrichment of different types of chromatin. Our results demonstrate that histone interacting domains are robust and highly specific reagents that can replace or complement histone modification antibodies. These domains can be produced recombinantly in Escherichia coli at low cost and constant quality. Protein design of reading domains allows for generation of novel specificities, addition of affinity tags, and preparation of PTM binding pocket variants as matching negative controls, which is not possible with antibodies. © 2014 Kungulovski et al.; Published by Cold Spring Harbor Laboratory Press.

Generalized nucleation and looping model for epigenetic memory of histone modifications

PubMed Central

Erdel, Fabian; Greene, Eric C.

2016-01-01

Histone modifications can redistribute along the genome in a sequence-independent manner, giving rise to chromatin position effects and epigenetic memory. The underlying mechanisms shape the endogenous chromatin landscape and determine its response to ectopically targeted histone modifiers. Here, we simulate linear and looping-driven spreading of histone modifications and compare both models to recent experiments on histone methylation in fission yeast. We find that a generalized nucleation-and-looping mechanism describes key observations on engineered and endogenous methylation domains including intrinsic spatial confinement, independent regulation of domain size and memory, variegation in the absence of antagonists, and coexistence of short- and long-term memory at loci with weak and strong constitutive nucleation. These findings support a straightforward relationship between the biochemical properties of chromatin modifiers and the spatiotemporal modification pattern. The proposed mechanism gives rise to a phase diagram for cellular memory that may be generally applicable to explain epigenetic phenomena across different species. PMID:27382173

ENHANCED STREAM WATER QUALITY MODELS QUAL2E AND QUAL2E-UNCAS: DOCUMENTATION AND USER MANUAL

EPA Science Inventory

The manual is a major revision of the original QUAL2E program documentation released in 1985. It includes a description of the recent modifications and improvements to the widely used water quality models QUAL-II and QUAL2E. The enhancements include an extensive capability for un...

40 CFR 725.984 - Modification or revocation of certain notification requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... software. Support documents related to these requests must also be submitted to EPA via CDX using e-PMN software. Paper requests must be submitted either via U.S. mail to the Document Control Office (DCO) (7407M... in § 725.980 may occur either at EPA's initiative or in response to a written request. (1) Any...

40 CFR 725.984 - Modification or revocation of certain notification requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... software. Support documents related to these requests must also be submitted to EPA via CDX using e-PMN software. Paper requests must be submitted either via U.S. mail to the Document Control Office (DCO) (7407M... in § 725.980 may occur either at EPA's initiative or in response to a written request. (1) Any...

Bibliometric analysis of nutrition and dietetics research activity in Arab countries using ISI Web of Science database.

PubMed

Sweileh, Waleed M; Al-Jabi, Samah W; Sawalha, Ansam F; Zyoud, Sa'ed H

2014-01-01

Reducing nutrition-related health problems in Arab countries requires an understanding of the performance of Arab countries in the field of nutrition and dietetics research. Assessment of research activity from a particular country or region could be achieved through bibliometric analysis. This study was carried out to investigate research activity in "nutrition and dietetics" in Arab countries. Original and review articles published from Arab countries in "nutrition and dietetics" Web of Science category up until 2012 were retrieved and analyzed using the ISI Web of Science database. The total number of documents published in "nutrition and dietetics" category from Arab countries was 2062. This constitutes 1% of worldwide research activity in the field. Annual research productivity showed a significant increase after 2005. Approximately 60% of published documents originated from three Arab countries, particularly Egypt, Kingdom of Saudi Arabia, and Tunisia. However, Kuwait has the highest research productivity per million inhabitants. Main research areas of published documents were in "Food Science/Technology" and "Chemistry" which constituted 75% of published documents compared with 25% for worldwide documents in nutrition and dietetics. A total of 329 (15.96%) nutrition - related diabetes or obesity or cancer documents were published from Arab countries compared with 21% for worldwide published documents. Interest in nutrition and dietetics research is relatively recent in Arab countries. Focus of nutrition research is mainly toward food technology and chemistry with lesser activity toward nutrition-related health research. International cooperation in nutrition research will definitely help Arab researchers in implementing nutrition research that will lead to better national policies regarding nutrition.

Proyecto de Ley por el Cual se Dicta el Estatuto General de Educacion y Pliego de Modificaciones Propuesto (Bill Establishing a General Statute for Education and Explanation of Proposed Modifications).

ERIC Educational Resources Information Center

Suarez Villa, Diego

This document contains the 1971 Colombian education bill and suggested bill modifications. The bill states educational objectives and establishes the structure of the national education system, the organization for educational administration, financing procedures, regulations for educational personnel, and the means for implementing the…

Indiana Air Pollution Control Board Approves a Modification on a PSD Permit for General Motors in which Two Coal-Fired Boilers are Forgiven a SO2 Control Requirement

EPA Pesticide Factsheets

This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

The TMIS life-cycle process document, revision A

NASA Technical Reports Server (NTRS)

1991-01-01

The Technical and Management Information System (TMIS) Life-Cycle Process Document describes the processes that shall be followed in the definition, design, development, test, deployment, and operation of all TMIS products and data base applications. This document is a roll out of TMIS Standards Document (SSP 30546). The purpose of this document is to define the life cycle methodology that the developers of all products and data base applications and any subsequent modifications shall follow. Included in this methodology are descriptions of the tasks, deliverables, reviews, and approvals that are required before a product or data base application is accepted in the TMIS environment.

Biodegradation of clotrimazole and modification of cell properties after metabolic stress and upon addition of saponins.

PubMed

Pacholak, A; Simlat, J; Zgoła-Grześkowiak, A; Kaczorek, E

2018-06-20

Azole fungicides constitute an extensive group of potential emerging pollutants which can be found in natural environment. This study focuses on the biodegradation of clotrimazole and the characterization of cell surface properties of microorganisms capable of degradation of this compound. The influence of long-term contact of bacteria with clotrimazole and the impact of the addition of Saponaria officinalis extract on cell surface modification was also checked. The biodegradation of clotrimazole did not exceed 70%. The presence of plant extract increased biodegradation of fungicide. The cells metabolic activity after one-month exposure to clotrimazole was the highest for each tested strain. Moreover, metabolic stress led to a strong modification of cell surface properties. The results are promising for determining the impact of clotrimazole on environmental microorganisms. Copyright © 2018 Elsevier Inc. All rights reserved.

Constitutional limits to the financing of health care in the Czech Republic and in selected European countries.

PubMed

Prudil, Lukás

2003-01-01

The aim of this paper is to describe the constitutional limits to the financing of health care and especially of public health insurance in the Czech Republic. It describes the current situation in the financing of health care on the basis of the Czech constitutional order as it has been interpreted by the Constitutional Court. Finally it presents an overview of the incorporation of the right to health into the constitutional documents of several European countries with the stress on the right to receive health care "free of charge". It is not typical within the European region to specify in constitutional acts to what extent it is giving the right to health care free-of-charge or more precisely to what extent and for what groups health care is paid for by persons other than by the citizens (patients). The Czech Republic is one of the exceptional cases in which the basic right to health care free-of-charge on the basis of public insurance is given directly by the Constitution.

Superfund record of decision amendment (EPA Region 5): Arrowhead Refinery Company, Hermantown, MN, February 9, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This decision document amends the selected remedial action for the Arrowhead Refinery Superfund Site (Arrowhead). This AROD does not make `fundamental changes` to the groundwater remedy selected in the ROD. Therefore, this AROD does not constitute an amendment of the groundwater remedy. However, this AROD does document minor differences in the groundwater remedy which the Agency intends to implement.

Annual National Report of the Australian Vocational Education and Training System, 2001. Volume 1: National Overview; Volume 2: Commonwealth, State & Territory Reports.

ERIC Educational Resources Information Center

Australian National Training Authority, Brisbane.

This document contains the first two volumes of a three-volume annual national report on Australia's vocational education and training (VET) system. Volume 1, which constitutes approximately 30% of the document, details progress in achieving the following national priorities: (1) a quality national training system that provides value for money…

The War in Vietnam: A Story in Photographs. The Constitution Community: Postwar United States (1945 to Early 1970s).

ERIC Educational Resources Information Center

Clark, Linda Darus

During the Vietnam War, the U.S. military gave the press unprecedented freedom of access to combat zones. This allowed newspaper reporters, photographers, and television crews to document a war involving U.S. sons and daughters on the other side of the world. This willingness to allow war documentation also was extended to the military's own…

Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeTar, Carleton

This document constitutes the Final Report for award DE-FC02-06ER41446 as required by the Office of Science. It summarizes accomplishments and provides copies of scientific publications with significant contribution from this award.

Transgenic expression of medicago truncatula PR10 and PR5 promoters in alfalfa shows pathogen-induced up-regulation of transgene expression

USDA-ARS?s Scientific Manuscript database

Genetic modification of alfalfa to introduce novel traits requires promoters for controlling gene expression. Promoters that are constitutively activated for expression of genes that enhance disease resistance pose a great energy load on the plant and exert a strong selective pressure on the pathoge...

Development of a Flow Field for Testing a Boundary-Layer-Ingesting Propulsor

NASA Technical Reports Server (NTRS)

Hirt, Stefanie M.; Arend, David J.; Wolter, John D.; Johnson, Aaron

2017-01-01

In order to test embedded-propulsor technology, modifications were required of the 8x6 Supersonic Wind tunnel at NASA Glenn Research Center. The extent of the modifications required that a new tunnel calibration be completed to generate a new calibration dataset and operational procedures for the tunnel, as well as to map the boundary layer on the raised floor. This report describes the propulsor inflow that was to be simulated, documents the tunnel modifications that were required, and conveys the results of the calibration test that was completed to measure the resulting flow properties.

Documentation for the machine-readable version of the Morphological Catalogue of Galaxies (MCG) of Vorontsov-Velyaminov et al, 1962-1968

NASA Technical Reports Server (NTRS)

Warren, W. H., Jr.

1982-01-01

Modifications, corrections, and the record format are provided for the machine-readable version of the "Morphological Catalogue of Galaxies.' In addition to hundreds of individual corrections, a detailed comparison of the machine-readable with the published catalogue resulted in the addition of 116 missing objects, the deletion of 10 duplicate records, and a format modification to increase storage efficiency.

An internal variable constitutive model for the large deformation of metals at high temperatures

NASA Technical Reports Server (NTRS)

Brown, Stuart; Anand, Lallit

1988-01-01

The advent of large deformation finite element methodologies is beginning to permit the numerical simulation of hot working processes whose design until recently has been based on prior industrial experience. Proper application of such finite element techniques requires realistic constitutive equations which more accurately model material behavior during hot working. A simple constitutive model for hot working is the single scalar internal variable model for isotropic thermal elastoplasticity proposed by Anand. The model is recalled and the specific scalar functions, for the equivalent plastic strain rate and the evolution equation for the internal variable, presented are slight modifications of those proposed by Anand. The modified functions are better able to represent high temperature material behavior. The monotonic constant true strain rate and strain rate jump compression experiments on a 2 percent silicon iron is briefly described. The model is implemented in the general purpose finite element program ABAQUS.

Research and development program for the development of advanced time-temperature dependent constitutive relationships. Volume 1: Theoretical discussion

NASA Technical Reports Server (NTRS)

Cassenti, B. N.

1983-01-01

The results of a 10-month research and development program for the development of advanced time-temperature constitutive relationships are presented. The program included (1) the effect of rate of change of temperature, (2) the development of a term to include time independent effects, and (3) improvements in computational efficiency. It was shown that rate of change of temperature could have a substantial effect on the predicted material response. A modification to include time-independent effects, applicable to many viscoplastic constitutive theories, was shown to reduce to classical plasticity. The computation time can be reduced by a factor of two if self-adaptive integration is used when compared to an integration using ordinary forward differences. During the course of the investigation, it was demonstrated that the most important single factor affecting the theoretical accuracy was the choice of material parameters.

Fatigue strength reduction model: RANDOM3 and RANDOM4 user manual. Appendix 2: Development of advanced methodologies for probabilistic constitutive relationships of material strength models

NASA Technical Reports Server (NTRS)

Boyce, Lola; Lovelace, Thomas B.

1989-01-01

FORTRAN programs RANDOM3 and RANDOM4 are documented in the form of a user's manual. Both programs are based on fatigue strength reduction, using a probabilistic constitutive model. The programs predict the random lifetime of an engine component to reach a given fatigue strength. The theoretical backgrounds, input data instructions, and sample problems illustrating the use of the programs are included.

Documentation: Records and Reports.

PubMed

Akers, Michael J

2017-01-01

This article deals with documentation to include the beginning of documentation, the requirements of Good Manufacturing Practice reports and records, and the steps that can be taken to minimize Good Manufacturing Practice documentation problems. It is important to remember that documentation for 503a compounding involves the Formulation Record, Compounding Record, Standard Operating Procedures, Safety Data Sheets, etc. For 503b outsourcing facilities, compliance with Current Good Manufacturing Practices is required, so this article is applicable to them. For 503a pharmacies, one can see the development and modification of Good Manufacturing Practice and even observe changes as they are occurring in 503a documentation requirements and anticipate that changes will probably continue to occur. Copyright© by International Journal of Pharmaceutical Compounding, Inc.

Neuroendorine and Epigentic Mechanisms Subserving Autonomic Imbalance and HPA Dysfunction in the Metabolic Syndrome

PubMed Central

Lemche, Erwin; Chaban, Oleg S.; Lemche, Alexandra V.

2016-01-01

Impact of environmental stress upon pathophysiology of the metabolic syndrome (MetS) has been substantiated by epidemiological, psychophysiological, and endocrinological studies. This review discusses recent advances in the understanding of causative roles of nutritional factors, sympathomedullo-adrenal (SMA) and hypothalamic-pituitary adrenocortical (HPA) axes, and adipose tissue chronic low-grade inflammation processes in MetS. Disturbances in the neuroendocrine systems for leptin, melanocortin, and neuropeptide Y (NPY)/agouti-related protein systems have been found resulting directly in MetS-like conditions. The review identifies candidate risk genes from factors shown critical for the functioning of each of these neuroendocrine signaling cascades. In its meta-analytic part, recent studies in epigenetic modification (histone methylation, acetylation, phosphorylation, ubiquitination) and posttranscriptional gene regulation by microRNAs are evaluated. Several studies suggest modification mechanisms of early life stress (ELS) and diet-induced obesity (DIO) programming in the hypothalamic regions with populations of POMC-expressing neurons. Epigenetic modifications were found in cortisol (here HSD11B1 expression), melanocortin, leptin, NPY, and adiponectin genes. With respect to adiposity genes, epigenetic modifications were documented for fat mass gene cluster APOA1/C3/A4/A5, and the lipolysis gene LIPE. With regard to inflammatory, immune and subcellular metabolism, PPARG, NKBF1, TNFA, TCF7C2, and those genes expressing cytochrome P450 family enzymes involved in steroidogenesis and in hepatic lipoproteins were documented for epigenetic modifications. PMID:27147943

29 CFR 779.111 - Buyers and their assistants.

Code of Federal Regulations, 2010 CFR

2010-07-01

... or other documents. These activities of such employees constitute engagement “in commerce” within the... Coverage Employees Engaged in Commerce Or in the Production of Goods for Commerce § 779.111 Buyers and...

29 CFR 779.111 - Buyers and their assistants.

Code of Federal Regulations, 2011 CFR

2011-07-01

... or other documents. These activities of such employees constitute engagement “in commerce” within the... Coverage Employees Engaged in Commerce Or in the Production of Goods for Commerce § 779.111 Buyers and...

12 CFR 308.24 - Scope of document discovery.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the Constitution, any applicable act of Congress, or the principles of common law provide. (d) Time... be permitted, unless the administrative law judge finds on the record that good cause exists for...

Selection process for trade study: Reusable Hydrogen Composite Tank System (RHCTS)

NASA Astrophysics Data System (ADS)

Greenberg, H. S.

1994-09-01

This document describes the selection process that will be used to identify the most suitable structural configuration option for an SSTO winged vehicle capable of delivering 25,000 lbs to a 220 nm circular orbit at 51.6 degree inclination. The most suitable RHCTS is within this configuration and will be the prototype design for subsequent design and analysis and the basis for the design and fabrication of a scale test article to be subjected to life cycle testing. The selection process for this TA 1 trade study is the same as that for the TA 2 trade study. As the trade study progresses additional insight may result in modifications to the selection criteria within in this process. Such modifications will result in an update of this document as appropriate.

Epigenetic regulation of vascular smooth muscle cell function in atherosclerosis.

PubMed

Findeisen, Hannes M; Kahles, Florian K; Bruemmer, Dennis

2013-04-01

Epigenetics involve heritable and acquired changes in gene transcription that occur independently of the DNA sequence. Epigenetic mechanisms constitute a hierarchic upper-level of transcriptional control through complex modifications of chromosomal components and nuclear structures. These modifications include, for example, DNA methylation or post-translational modifications of core histones; they are mediated by various chromatin-modifying enzymes; and ultimately they define the accessibility of a transcriptional complex to its target DNA. Integrating epigenetic mechanisms into the pathophysiologic concept of complex and multifactorial diseases such as atherosclerosis may significantly enhance our understanding of related mechanisms and provide promising therapeutic approaches. Although still in its infancy, intriguing scientific progress has begun to elucidate the role of epigenetic mechanisms in vascular biology, particularly in the control of smooth muscle cell phenotypes. In this review, we will summarize epigenetic pathways in smooth muscle cells, focusing on mechanisms involved in the regulation of vascular remodeling.

Epigenetic regulation of vascular smooth muscle cell function in atherosclerosis.

PubMed

Findeisen, Hannes M; Kahles, Florian K; Bruemmer, Dennis

2013-05-01

Epigenetics involve heritable and acquired changes in gene transcription that occur independently of the DNA sequence. Epigenetic mechanisms constitute a hierarchic upper-level of transcriptional control through complex modifications of chromosomal components and nuclear structures. These modifications include, for example, DNA methylation or post-translational modifications of core histones; they are mediated by various chromatin-modifying enzymes; and ultimately they define the accessibility of a transcriptional complex to its target DNA. Integrating epigenetic mechanisms into the pathophysiologic concept of complex and multifactorial diseases such as atherosclerosis may significantly enhance our understanding of related mechanisms and provide promising therapeutic approaches. Although still in its infancy, intriguing scientific progress has begun to elucidate the role of epigenetic mechanisms in vascular biology, particularly in the control of smooth muscle cell phenotypes. In this review, we will summarize epigenetic pathways in smooth muscle cells, focusing on mechanisms involved in the regulation of vascular remodeling.

Chemical modification of coating of Pinus halepensis pollen by ozone exposure.

PubMed

Naas, Oumsaad; Mendez, Maxence; Quijada, Melesio; Gosselin, Sylvie; Farah, Jinane; Choukri, Ali; Visez, Nicolas

2016-07-01

Pollen coating, located on the exine, includes an extractible lipid fraction. The modification of the pollen coating by air pollutants may have implications on the interactions of pollen with plant stigmas and human cells. Pinus halepensis pollen was exposed to ozone in vitro and the pollen coating was extracted with organic solvent and analyzed by GC-MS. Ozone has induced chemical changes in the coating as observed with an increase in dicarboxylic acids, short-chain fatty acids and aldehydes. 4-Hydroxybenzaldehyde was identified as the main reaction product and its formation was shown to occur both on native pollen and on defatted pollen. 4-Hydroxybenzaldehyde is very likely formed via the ozonolysis of acid coumaric-like monomers constitutive of the sporopollenin. Modification of pollen coating by air pollutants should be accounted for in further studies on effect of pollution on germination and on allergenicity. Copyright © 2016 Elsevier Ltd. All rights reserved.

Histones: Controlling Tumor Signaling Circuitry

PubMed Central

Martins, Manoela D.; Castilho, Rogerio M.

2014-01-01

Epigenetic modifications constitute the next frontier in tumor biology research. Post-translation modification of histones dynamically influences gene expression independent of alterations to the DNA sequence. These mechanisms are often mediated by histone linkers or by proteins associated with the recruitment of DNA-binding proteins, HDAC I and II interacting proteins and transcriptional activators, coactivators or corepressors. Early evidence suggested that histones and their modifiers are involved in sophisticated processes that modulate tumor behavior and cellular phenotype. In this review, we discuss how recent discoveries about chromatin modifications, particularly histone acetylation, are shaping our knowledge of cell biology and our understanding of the molecular circuitry governing tumor progression and consider whether recent insights may extend to novel therapeutic approaches. Furthermore, we discuss the latest oncogenomic findings in Head and Neck Squamous Cell Carcinoma (HNSCC) from studies using Next Generation Sequencing (NGS) technology and highlight the impact of mutations identified in histones and their modifiers. PMID:25177526

Ongoing modification of Mediterranean Pleistocene sapropels mediated by prokaryotes.

PubMed

Coolen, Marco J L; Cypionka, Heribert; Sass, Andrea M; Sass, Henrik; Overmann, Jörg

2002-06-28

Late Pleistocene organic-rich sediments (sapropels) from the eastern Mediterranean Sea harbor unknown, metabolically active chemoorganotrophic prokaryotes. As compared to the carbon-lean intermediate layers, sapropels exhibit elevated cell numbers, increased activities of hydrolytic exoenzymes, and increased anaerobic glucose degradation rates, suggesting that microbial carbon substrates originate from sapropel layers up to 217,000 years old. 16S ribosomal RNA gene analyses revealed that as-yet-uncultured green nonsulfur bacteria constitute up to 70% of the total microbial biomass. Crenarchaeota constitute a smaller fraction (on average, 16%). A slow but significant turnover of glucose could be detected. Apparently, sapropels are still altered by the metabolic activity of green nonsulfur bacteria and crenarchaeota.

A Generalization of the Einstein-Maxwell Equations

NASA Astrophysics Data System (ADS)

Cotton, Fredrick

2016-03-01

The proposed modifications of the Einstein-Maxwell equations include: (1) the addition of a scalar term to the electromagnetic side of the equation rather than to the gravitational side, (2) the introduction of a 4-dimensional, nonlinear electromagnetic constitutive tensor and (3) the addition of curvature terms arising from the non-metric components of a general symmetric connection. The scalar term is defined by the condition that a spherically symmetric particle be force-free and mathematically well-behaved everywhere. The constitutive tensor introduces two auxiliary fields which describe the particle structure. The additional curvature terms couple both to particle solutions and to electromagnetic and gravitational wave solutions. http://sites.google.com/site/fwcotton/em-30.pdf

U.S. Constitution Course

Science.gov Websites

to assist DoD employees in learning more about this most powerful and enduring document, the U.S . Print your certificate. There are several learning objectives for this course. At the conclusion of the

Administrative Subpoenas in Criminal Investigations: A Brief Legal Analysis

DTIC Science & Technology

2006-03-17

child abuse , Secret Service protection, controlled substance cases, and Inspector General investigations. As a constitutional matter, the Fourth Amendment only demands that administrative subpoenas be reasonable, a standard that requires that 1) they satisfy the terms of the authorizing statute, 2) the documents requested are relevant to the investigation, 3) the information sought is not already in the government’s possession, and 4) enforcing the subpoena will not constitute an abuse of the court’s process. Although more extensive proposals were offered in the

Air National Guard Installation Restoration Program Site Investigation Report, 185th Tactical Fighter Group, Iowa Air National Guard, Sioux Gateway Airport, Sergeant Bluff, Iowa

DTIC Science & Technology

1991-10-01

during the RI; or to provide information for the determination that no further action is required if risks to human and environmental receptors are not...constitute an environmental risk . Exposure media and routes may differ between various organisms due to their physiological and behavioral differences...important species are relatively well documented. U Groundwater 3 Groundwater contaminants may constitute a risk to environmental receptors when

[The new Colombian criminal code and biotechnology].

PubMed

González de Cancino, Emilssen

2002-01-01

The author describes the process by which new offenses concerning biotechnology have been included in Colombia's Penal Code and discusses some of the more controversial aspects involved. She examines the various stages of the passage of the Bill through Parliament and the modifications undergone. She also provides well-argued criticism of the text, with appropriate reference to Constitutional provisions regarding the rights concerned.

Epigenetic modifications and chromatin loop organization explain the different expression profiles of the Tbrg4, WAP and Ramp3 genes

USDA-ARS?s Scientific Manuscript database

Whey Acidic Protein (WAP) gene expression is specific to the mammary gland and regulated by lactogenic hormones to peak during lactation. It differs markedly from the more constitutive expression of the two flanking genes, Ramp3 and Tbrg4. Our results show that the tight regulation of WAP gene expre...

Flight Experiment Demonstration System (FEDS) functional description and interface document

NASA Technical Reports Server (NTRS)

Belcher, R. C.; Shank, D. E.

1984-01-01

This document presents a functional description of the Flight Experiment Demonstration System (FEDS) and of interfaces between FEDS and external hardware and software. FEDS is a modification of the Automated Orbit Determination System (AODS). FEDS has been developed to support a ground demonstration of microprocessor-based onboard orbit determination. This document provides an overview of the structure and logic of FEDS and details the various operational procedures to build and execute FEDS. It also documents a microprocessor interface between FEDS and a TDRSS user transponder and describes a software simulator of the interface used in the development and system testing of FEDS.

Recommendations and Justifications To Remove Use Restrictions Established under the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office Federal Facility Agreement and Consent Order, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Birney, Cathleen; Krauss, Mark J

This document is part of an effort to reevaluate 37 FFACO and Administrative URs against the current Soils Risk-Based Corrective Action Evaluation Process. After reviewing 37 existing FFACO and Administrative URs, 3 URs addressed in this document have sufficient information to determine that these current URs may be removed, based on the RBCA criteria. This document presents recommendations on modifications to existing URs that will be consistent with the RBCA criteria.

Exploring peptide hormones in plants: identification of four peptide hormone-receptor pairs and two post-translational modification enzymes

PubMed Central

MATSUBAYASHI, Yoshikatsu

2018-01-01

The identification of hormones and their receptors in multicellular organisms is one of the most exciting research areas and has lead to breakthroughs in understanding how their growth and development are regulated. In particular, peptide hormones offer advantages as cell-to-cell signals in that they can be synthesized rapidly and have the greatest diversity in their structure and function. Peptides often undergo post-translational modifications and proteolytic processing to generate small oligopeptide hormones. In plants, such small post-translationally modified peptides constitute the largest group of peptide hormones. We initially explored this type of peptide hormone using bioassay-guided fractionation and later by in silico gene screening coupled with biochemical peptide detection, which led to the identification of four types of novel peptide hormones in plants. We also identified specific receptors for these peptides and transferases required for their post-translational modification. This review summarizes how we discovered these peptide hormone–receptor pairs and post-translational modification enzymes, and how these molecules function in plant growth, development and environmental adaptation. PMID:29434080

Exploring peptide hormones in plants: identification of four peptide hormone-receptor pairs and two post-translational modification enzymes.

PubMed

Matsubayashi, Yoshikatsu

2018-01-01

The identification of hormones and their receptors in multicellular organisms is one of the most exciting research areas and has lead to breakthroughs in understanding how their growth and development are regulated. In particular, peptide hormones offer advantages as cell-to-cell signals in that they can be synthesized rapidly and have the greatest diversity in their structure and function. Peptides often undergo post-translational modifications and proteolytic processing to generate small oligopeptide hormones. In plants, such small post-translationally modified peptides constitute the largest group of peptide hormones. We initially explored this type of peptide hormone using bioassay-guided fractionation and later by in silico gene screening coupled with biochemical peptide detection, which led to the identification of four types of novel peptide hormones in plants. We also identified specific receptors for these peptides and transferases required for their post-translational modification. This review summarizes how we discovered these peptide hormone-receptor pairs and post-translational modification enzymes, and how these molecules function in plant growth, development and environmental adaptation.

Modeling unsaturated zone flow and runoff processes by integrating MODFLOW-LGR and VSF, and creating the new CFL package

USGS Publications Warehouse

Borsia, I.; Rossetto, R.; Schifani, C.; Hill, Mary C.

2013-01-01

In this paper two modifications to the MODFLOW code are presented. One concerns an extension of Local Grid Refinement (LGR) to Variable Saturated Flow process (VSF) capability. This modification allows the user to solve the 3D Richards’ equation only in selected parts of the model domain. The second modification introduces a new package, named CFL (Cascading Flow), which improves the computation of overland flow when ground surface saturation is simulated using either VSF or the Unsaturated Zone Flow (UZF) package. The modeling concepts are presented and demonstrated. Programmer documentation is included in appendices.

2002 Controls Design Challenge

NASA Technical Reports Server (NTRS)

Hess, Ronald A.; Vetter, T. K.; Wells, S. R.

2002-01-01

This document is intended to provide the specifications and requirements for a flight control system design challenge. The response to the challenge will involve documenting whether the particular design has met the stated requirements through analysis and computer simulation. The response should be written in the general format of a technical publication with corresponding length limits, e.g., an approximate maximum length of 45 units, with each full-size figure and double-spaced typewritten page constituting one unit.

Calibration, Verification and Application of a Two-Dimensional Flow Model.

DTIC Science & Technology

1983-09-01

report are not to be construed as an official Department of the Army position unless so designated by other athorized documents. The contents of this... report are not to be used for advertising, publication. or promotional purposes. Citation of trade names does not constitute an official 6hdorsement...or approval of the use of such commercial products. Unclassified SECURITY CLASSIFICATION o THIS PAGE ("O~en Dato Ene_ _ _ REPORT DOCUMENTATION PAGE AD

Is there an association with constitutional structural chromosomal abnormalities and hematologic neoplastic process? A short review.

PubMed

Panani, Anna D

2009-04-01

The occasional observation of constitutional chromosomal abnormalities in patients with a malignant disease has led to a number of studies on their potential role in cancer development. Investigations of families with hereditary cancers and constitutional chromosomal abnormalities have been key observations leading to the molecular identification of specific genes implicated in tumorigenesis. Large studies have been reported on the incidence of constitutional chromosomal aberrations in patients with hematologic malignancies, but they could not confirm an increased risk for hematologic malignancy among carriers of structural chromosomal changes. However, it is of particular interest that constitutional structural aberrations with breakpoints similar to leukemia-associated specific breakpoints have been reported in patients with hematologic malignancies. Because of insufficient data, it remains still unclear if these aberrations represent random events or are associated with malignancy. There has been a substantial discussion about mechanisms involved in constitutional structural chromosomal changes in the literature. The documentation of more patients with constitutional structural chromosomal changes could be of major importance. Most importantly, the molecular investigation of chromosomal regions involved in rearrangements could give useful information on the genetic events underlying constitutional anomalies, contributing to isolation of genes important in the development of the neoplastic process. Regarding constitutional anomalies in patients with hematologic disorders, a survey of the cytogenetic data of our cytogenetics unit is herein also presented.

Computer program documentation modified version of the JA70 aerodynamic heating computer program H800 (MINIVER with a DISSPLA plot package

NASA Technical Reports Server (NTRS)

Olmedo, L.

1980-01-01

The changes, modifications, and inclusions which were adapted to the current version of the MINIVER program are discussed. Extensive modifications were made to various subroutines, and a new plot package added. This plot package is the Johnson Space Center DISSPLA Graphics System currently driven under an 1110 EXEC 8 configuration. User instructions on executing the MINIVER program are provided and the plot package is described.

Science and Engineering Technical Assessments (SETA) Program

NASA Technical Reports Server (NTRS)

Huy, Frank

2000-01-01

This document provides a project plan for the D.N. American response to Modification #1 to Contract Task Order #13 - Program Maintenance and Logistics for the Science and Engineering Technical Assessments (SETA) contract.

Position statement and guidelines on unmodified electroconvulsive therapy

PubMed Central

Andrade, Chittaranjan; Shah, N.; Tharyan, P.; Reddy, M. S.; Thirunavukarasu, M.; Kallivayalil, R. A.; Nagpal, R.; Bohra, N. K.; Sharma, A.; Mohandas, E.

2012-01-01

Background: In modern day psychiatric practice, it is assumed as a matter of fact that when electroconvulsive therapy (ECT) is administered, it will be administered under anesthesia and with succinylcholine (or its equivalent) modification. Yet, as surveys indicate, there is considerable practice of unmodified ECT in developing countries and, to a small extent, in the developed world, as well. Materials and Methods: This document examines historical and recent literature on the geographical practice, physiology, efficacy, and adverse effects of unmodified ECT. Particular attention is paid to musculoskeletal risks. Results: Although almost all the research is of poor methodological quality, there is a good reason to accept that unmodified ECT is associated with a wide range of adverse consequences, important among which are musculoskeletal complications, pre-ECT anxiety, and post-ECT confusion. However, it appears from recent data that these risks are not as large as historically portrayed. Possibly explanations are suggested, with seizure modification using parenteral benzodiazepines as a special possibility. Conclusions: Under exceptional circumstances, if ECT is strongly indicated and seizure modification with succinylcholine is not feasible, unmodified ECT, especially benzodiazepine-modified ECT, may be a viable option. A detailed set of recommendations for such use of unmodified ECT is proposed along with necessary checks and balances. This document has been approved by the Indian Psychatric Society, the Indian Association of Biological Psychiatry, and the Indian Association of Private Psychiatry (which commissioned the preparation of the document). PMID:22988318

[Epigenetic alterations in acute lymphoblastic leukemia].

PubMed

Navarrete-Meneses, María Del Pilar; Pérez-Vera, Patricia

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. It is well-known that genetic alterations constitute the basis for the etiology of ALL. However, genetic abnormalities are not enough for the complete development of the disease, and additional alterations such as epigenetic modifications are required. Such alterations, like DNA methylation, histone modifications, and noncoding RNA regulation have been identified in ALL. DNA hypermethylation in promoter regions is one of the most frequent epigenetic modifications observed in ALL. This modification frequently leads to gene silencing in tumor suppressor genes, and in consequence, contributes to leukemogenesis. Alterations in histone remodeling proteins have also been detected in ALL, such as the overexpression of histone deacetylases enzymes, and alteration of acetyltransferases and methyltransferases. ALL also shows alteration in the expression of miRNAs, and in consequence, the modification in the expression of their target genes. All of these epigenetic modifications are key events in the malignant transformation since they lead to the deregulation of oncogenes as BLK, WNT5B and WISP1, and tumor suppressors such as FHIT, CDKN2A, CDKN2B, and TP53, which alter fundamental cellular processes and potentially lead to the development of ALL. Both genetic and epigenetic alterations contribute to the development and evolution of ALL. Copyright © 2017 Hospital Infantil de México Federico Gómez. Publicado por Masson Doyma México S.A. All rights reserved.

Histone modifications associated with both A and B chromosomes of maize.

PubMed

Jin, Weiwei; Lamb, Jonathan C; Zhang, Wenli; Kolano, Bozena; Birchler, James A; Jiang, Jiming

2008-01-01

We report the distribution of several histone modifications along the arms and in centromeric regions of somatic chromosomes of maize, including the supernumerary B chromosome. Acetylated H3 and H4 as well as H3K4me2, modifications associated with euchromatin, were enriched in the distal parts of the A chromosomes, but were progressively depleted toward the centromeres of the A chromosomes and were depleted in the heterochromatic portions of the B chromosome. Classical histone modifications associated with heterochromatin, including H3K9me2, H3K27me1 and H3K27me2, were distributed throughout both A and B chromosomes. However, H3K27me2 showed a reduced level on the B chromosome compared with the A chromosomes and was not associated with some classes of constitutive heterochromatin. We monitored the presence of each histone modification in the centromeric regions using a YFP-tagged centromere-specific histone, CENH3. We observed the presence of H3K9me2 and absence of H3K4me2 in the centromeric regions of both A and B chromosomes of maize, which is in contrast to the presence of H3K4me2 and absence of H3K9me2 in animal centromeres. These results show a diversity of epigenetic modifications associated with centromeric chromatin in different eukaryotes.

Reverse Induced Fit-Driven MAS-Downstream Transduction: Looking for Metabotropic Agonists.

PubMed

Pernomian, Larissa; Gomes, Mayara S; de Paula da Silva, Carlos H Tomich; Rosa, Joaquin M C

2017-01-01

Protective effects of MAS activation have spurred clinical interests in developing MAS agonists. However, current bases that drive this process preclude that physiological concentrations of peptide MAS agonists induce an atypical signaling that does not reach the metabotropic efficacy of constitutive activation. Canonical activation of MAS-coupled G proteins is only achieved by supraphysiological concentrations of peptide MAS agonists or physiological concentrations of chemically modified analogues. These pleiotropic differences are because of two overlapped binding domains: one non-metabotropic site that recognizes peptide agonists and one metabotropic domain that recognizes modified analogues. It is feasible that supraphysiological concentrations of peptide MAS agonists undergo to chemical modifications required for binding to metabotropic domain. Receptor oligomerization enhances pharmacological parameters coupled to metabotropic signaling. The formation of receptor-signalosome complex makes the transduction of agonists more adaptive. Considering the recent identification of MAS-signalosome, we aimed to postulate the reverse induced fit hypothesis in which MAS-signalosome would trigger chemical modifications required for agonists bind to MAS metabotropic domain. Here we cover rational perspectives for developing novel metabotropic MAS agonists in the view of the reverse induced-fit hypothesis. Predicting a 3D model of MAS metabotropic domain may guide the screening of chemical modifications required for metabotropic efficacy. Pharmacophore-based virtual screening would select potential metabotropic MAS agonists from virtual libraries from human proteome. Rational perspectives that consider reverse induced fit hypothesis during MAS activation for developing metabotropic MAS agonists represents the best approach in providing MAS ligands with constitutive efficacy at physiological concentrations. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

49 CFR 511.14 - Form and filing of documents.

Code of Federal Regulations, 2012 CFR

2012-10-01

... constitutes a representation by the signer that the signer has read it; that to the best of the signer's knowledge, information and belief, the statements made in it are true; and that it is not filed for purposes...

49 CFR 511.14 - Form and filing of documents.

Code of Federal Regulations, 2010 CFR

2010-10-01

... constitutes a representation by the signer that the signer has read it; that to the best of the signer's knowledge, information and belief, the statements made in it are true; and that it is not filed for purposes...

49 CFR 511.14 - Form and filing of documents.

Code of Federal Regulations, 2013 CFR

2013-10-01

... constitutes a representation by the signer that the signer has read it; that to the best of the signer's knowledge, information and belief, the statements made in it are true; and that it is not filed for purposes...

49 CFR 511.14 - Form and filing of documents.

Code of Federal Regulations, 2014 CFR

2014-10-01

... constitutes a representation by the signer that the signer has read it; that to the best of the signer's knowledge, information and belief, the statements made in it are true; and that it is not filed for purposes...

49 CFR 511.14 - Form and filing of documents.

Code of Federal Regulations, 2011 CFR

2011-10-01

... constitutes a representation by the signer that the signer has read it; that to the best of the signer's knowledge, information and belief, the statements made in it are true; and that it is not filed for purposes...

Region IV Transit Workshop: Harnessing the Private Sector

DOT National Transportation Integrated Search

1988-09-01

This Report constitutes the Proceedings of the Region IV Transit Workshop: : Harnessing the Private Sector. Included in this document is a general report of : the activities of the Workshop. : The purpose ot the Region IV Transit Workshop: Harnessing...

An analysis of the job of railroad train dispatcher.

DOT National Transportation Integrated Search

1974-04-01

This report constitutes a detailed study of the job of railroad train dispatcher, conducted to provide a data base for the derivation of criteria of job knowledge, skills and training consonant with safe operations. Documentation was reviewed; specia...

13 CFR 120.1720 - SBA's right to review Pool Loan documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... may constitute a material failure to comply with the Program Rules and Regulations and may lead to an... Program and may restrict further sales under the Program until SBA determines that the Seller has provided...

Ad-Hoc Networks and the Mobile Application Security System (MASS)

DTIC Science & Technology

2006-01-01

solution to this problem that addresses critical aspects of security in ad-hoc mobile application networks. This approach involves preventing unauthorized...modification of a mobile application , both by other applications and by hosts, and ensuring that mobile code is authentic and authorized. These...capabilities constitute the Mobile Application Security System (MASS). The MASS applies effective, robust security to mobile application -based systems

Integrated Analytical Evaluation and Optimization of Model Parameters against Preprocessed Measurement Data

DTIC Science & Technology

1989-06-23

Iterations .......................... 86 3.2 Comparison between MACH and POLAR ......................... 90 3.3 Flow Chart for VSTS Algorithm...The most recent changes are: a) development of the VSTS (velocity space topology search) algorithm for calculating particle densities b) extension...with simple analytic models. The largest modification of the MACH code was the implementation of the VSTS procedure, which constituted a complete

Drug discovery: phosphinolactone, in vivo bioisostere of the lactol group.

PubMed

Volle, Jean-Noël; Filippini, Damien; Krawczy, Bartlomiej; Kaloyanov, Nikolay; Van der Lee, Arie; Maurice, Tangui; Pirat, Jean-Luc; Virieux, David

2010-03-21

In drug discovery, structural modifications over the lead molecule are often crucial for the development of a drug. Herein, we reported the first in vivo bioisosteric effect of phosphinolactone function in relation to the lactol group constituting the bioactive molecule: Hydroxybupropion. The preparation of phosphinolactone analogues and their antidepressant evaluation towards forced swimming test in mice showed that biological activity was regained and even strengthen.

Posttranscriptional modification of tRNA in thermophilic archaea (Archaebacteria).

PubMed Central

Edmonds, C G; Crain, P F; Gupta, R; Hashizume, T; Hocart, C H; Kowalak, J A; Pomerantz, S C; Stetter, K O; McCloskey, J A

1991-01-01

Nucleoside modification has been studied in unfractionated tRNA from 11 thermophilic archaea (archaebacteria), including phylogenetically diverse representatives of thermophilic methanogens and sulfur-metabolizing hyperthermophiles which grow optimally in the temperature range of 56 (Thermoplasma acidophilum) to 105 degrees C (Pyrodictium occultum), and for comparison from the most thermophilic bacterium (eubacterium) known, Thermotoga maritima (80 degrees C). Nine nucleosides are found to be unique to the archaea, six of which are structurally novel in being modified both in the base and by methylation in ribose and occur primarily in tRNA from the extreme thermophiles in the Crenarchaeota of the archaeal phylogenetic tree. 2-Thiothymine occurs in tRNA from Thermococcus sp., and constitutes the only known occurrence of the thymine moiety in archaeal RNA, in contrast to its near-ubiquitous presence in tRNA from bacteria and eukarya. A total of 33 modified nucleosides are rigorously characterized in archaeal tRNA in the present study, demonstrating that the structural range of posttranscriptional modifications in archaeal tRNA is more extensive than previously known. From a phylogenetic standpoint, certain tRNA modifications occur in the archaea which are otherwise unique to either the bacterial or eukaryal domain, although the overall patterns of modification are more typical of eukaryotes than bacteria. PMID:1708763

On Relevance Weight Estimation and Query Expansion.

ERIC Educational Resources Information Center

Robertson, S. E.

1986-01-01

A Bayesian argument is used to suggest modifications to the Robertson and Jones relevance weighting formula to accommodate the addition to the query of terms taken from the relevant documents identified during the search. (Author)

Lightning and surge protection, grounding, bonding and shielding requirements for facilities and electronic equipment

DOT National Transportation Integrated Search

2002-08-09

This document mandates standard lightning protection, transient protection, electrostatic discharge (ESD), grounding, bonding and shielding configurations and procedures for new facilities, facility modifications, facility up grades, new equipment in...

Crater modification by gravity - A mechanical analysis of slumping. [on moon

NASA Technical Reports Server (NTRS)

Melosh, H. J.

1977-01-01

An analysis of the stability of a crater from a mechanical point of view indicates that the observed slumping of lunar craters requires a perfectly plastic constitutive relation for the lunar surface rock. The angle of internal friction of this material must be less than a few degrees. The evidence for a perfectly plastic constitutive relation is described, and a simplified model of a crater in a perfectly plastic medium is used to investigate the nature of its collapse. Crater stability is found to depend principally upon a dimensionless parameter equal to the product of the density, acceleration of gravity, and depth divided by the yield strength. Criteria for stability, 'slope failures', and 'floor failures' are reported.

Modifications to the modular three-dimensional finite-difference ground-water flow model used for the Columbia Plateau Regional Aquifer-System Analysis, Washington, Oregon, and Idaho

USGS Publications Warehouse

Hansen, A.J.

1993-01-01

The report documents modifications to the U.S. Geological Survey's modular three-dimensional finite-difference ground-water flow model used for a regional aquifer-system analysis of the Columbia Plateau. The report, which describes the concepts and mathematical basis for the modifications, is intended for potential users who are familiar with the original modular model. The modifications permit flow from a layer to any adjacent layer, allow the model to retain a cell of a layer that has been cut completely through by a canyon, and allow placing ground-water flow barriers on only specified branch conductances; a special version of the modified model uses a convergent grid. The report describes the data-input items that this modified model must read.

NASA reload program

NASA Technical Reports Server (NTRS)

Byington, Marshall

1993-01-01

Atlantic Research Corporation (ARC) contracted with NASA to manufacture and deliver thirteen small scale Solid Rocket Motors (SRM). These motors, containing five distinct propellant formulations, will be used for plume induced radiation studies. The information contained herein summarizes and documents the program accomplishments and results. Several modifications were made to the scope of work during the course of the program. The effort was on hold from late 1991 through August, 1992 while propellant formulation changes were developed. Modifications to the baseline program were completed in late-August and Modification No. 6 was received by ARC on September 14, 1992. The modifications include changes to the propellant formulation and the nozzle design. The required motor deliveries were completed in late-December, 1992. However, ARC agreed to perform an additional mix and cast effort at no cost to NASA and another motor was delivered in March, 1993.

AQUIFEM-SALT; a finite-element model for aquifers containing a seawater interface

USGS Publications Warehouse

Voss, C.I.

1984-01-01

Described are modifications to AQUIFEM, a finite element areal ground-water flow model for aquifer evaluation. The modified model, AQUIFEM-SALT, simulates an aquifer containing a freshwater body that freely floats on seawater. Parts of the freshwater lens may be confined above and below by less permeable units. Theory, code modifications, and model verification are discussed. A modified input data list is included. This report is intended as a companion to the original AQUIFEM documentation. (USGS)

DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes?

PubMed

Luo, Guan-Zheng; Blanco, Mario Andres; Greer, Eric Lieberman; He, Chuan; Shi, Yang

2015-12-01

DNA N(6)-adenine methylation (N(6)-methyladenine; 6mA) in prokaryotes functions primarily in the host defence system. The prevalence and significance of this modification in eukaryotes had been unclear until recently. Here, we discuss recent publications documenting the presence of 6mA in Chlamydomonas reinhardtii, Drosophila melanogaster and Caenorhabditis elegans; consider possible roles for this DNA modification in regulating transcription, the activity of transposable elements and transgenerational epigenetic inheritance; and propose 6mA as a new epigenetic mark in eukaryotes.

Atmospheric release model for the E-area low-level waste facility: Updates and modifications

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

The atmospheric release model (ARM) utilizes GoldSim® Monte Carlo simulation software (GTG, 2017) to evaluate the flux of gaseous radionuclides as they volatilize from E-Area disposal facility waste zones, diffuse into the air-filled soil pores surrounding the waste, and emanate at the land surface. This report documents the updates and modifications to the ARM for the next planned E-Area PA considering recommendations from the 2015 PA strategic planning team outlined by Butcher and Phifer.

[Constitutional syndrome associated to metformin induced hepatotoxicity].

PubMed

de la Poza Gómez, Gema; Rivero Fernández, Miguel; Vázquez Romero, Manuel; Angueira Lapeña, Teresa; Arranz de la Mata, Gemma; Boixeda de Miquel, Daniel

2008-12-01

Metformin is an oral antidiabetic agent frequently used to manage type II diabetes. This drug produces nonspecific gastrointestinal symptoms in 5-20% of patients and, more rarely, has also been associated with severe adverse effects such as lactic acidosis. Only a few isolated cases of hepatotoxicity due to this drug have been documented. We report the case of an 83-year-old man with constitutional syndrome and hepatic biochemical alterations, which were attributed to metformin after ruling out an oncologic etiology and observing complete clinical and biochemical resolution after withdrawal of the drug.

Resource Conservation and Recovery Act, Part B Permit Application [for the Waste Isolation Pilot Plant (WIPP)]. Volume 5, Chapter D, Appendix D1 (conclusion), Revision 3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, Neville G.W.; Heuze, Francois E.; Miller, Hamish D.S.

1993-03-01

The reference design for the underground facilities at the Waste Isolation Pilot Plant was developed using the best criteria available at initiation of the detailed design effort. These design criteria are contained in the US Department of Energy document titled Design Criteria, Waste Isolation Pilot Plant (WIPP). Revised Mission Concept-IIA (RMC-IIA), Rev. 4, dated February 1984. The validation process described in the Design Validation Final Report has resulted in validation of the reference design of the underground openings based on these criteria. Future changes may necessitate modification of the Design Criteria document and/or the reference design. Validation of the referencemore » design as presented in this report permits the consideration of future design or design criteria modifications necessitated by these changes or by experience gained at the WIPP. Any future modifications to the design criteria and/or the reference design will be governed by a DOE Standard Operation Procedure (SOP) covering underground design changes. This procedure will explain the process to be followed in describing, evaluating and approving the change.« less

25 CFR 101.13 - Security.

Code of Federal Regulations, 2010 CFR

2010-04-01

... income will be adequate to pay all expenses and the loan principal and interest payments, indicating... will be adequate to pay all expenses and the loan principal and interest payments, indicating... constitutions and bylaws, corporate charters, or other organizational documents when mortgaging tribal property...

Emergency communications for evacuation (EVAC) in New Orleans impact assessment report.

DOT National Transportation Integrated Search

2015-05-01

This document constitutes the Impact Assessment Report for Emergency Communications for Evacuation (EVAC) in New Orleans. Response, Emergency Staging and Communications, Uniform Management, and Evacuation (R.E.S.C.U.M.E.) is a bundle of applications ...

USDOT’s Intelligent Transportation Systems (ITS) ITS strategic plan, 2015-2019.

DOT National Transportation Integrated Search

2014-05-01

This document constitutes the Intelligent Transportation Systems Strategic Plan covering the years 2015 to 2019; it builds on the progress of the 2010-2014 plan and presents a wide array of technical, policy, institutional, and organizational concept...

Evaluation of TravInfo field operational test

DOT National Transportation Integrated Search

2000-04-25

This document constitutes the final report of the evaluation of the TravInfo field operational test. TravInfo is a regional traveler information system in operation in the San Francisco Bay Area. The focus of the evaluation was on three areas: instit...

AIR QUALITY CRITERIA FOR LEAD (1977)

EPA Science Inventory

The document summarizes current knowledge about the relationships between airborne lead and consequent effects on man and his environment. The effects that have been observed to occur when airborne lead has reached or exceeded specific levels for time periods constitute the centr...

The constitutionality of mandatory seat belt laws.

DOT National Transportation Integrated Search

1986-01-01

Low seat belt usage rates have persisted for years despite efforts to educate people about belts' benefits. There is ample documentation of the contribution of seat belts to saving lives and reducing injury. The emotional and pecuniary toll of the fa...

Using highways during evacuation operations for events with advance notice

DOT National Transportation Integrated Search

2006-12-01

This document constitutes the first of a primer series titled 'Routes to Effective Evacuation planning' and covers the use of the highway system during evacuation operations when advance planning is possible [...] This is a basic-level guide on condu...

ITC field test memorandum for Independence National Historical Park.

DOT National Transportation Integrated Search

2000-12-01

This memorandum documents a field test conducted on October 26, 2000 in Philadelphia, PA for the proposed Independence Transportation Center (ITC). The ITC is a bus depot to support visitation to the National Constitution Center (NCC) and the Nationa...

Higher-order theories of gravity: diagnosis, extraction and reformulation via non-metric extra degrees of freedom—a review

NASA Astrophysics Data System (ADS)

Belenchia, Alessio; Letizia, Marco; Liberati, Stefano; Di Casola, Eolo

2018-03-01

Modifications of Einstein’s theory of gravitation have been extensively considered in the past years, in connection to both cosmology and quantum gravity. Higher-curvature and higher-derivative gravity theories constitute the main examples of such modifications. These theories exhibit, in general, more degrees of freedom than those found in standard general relativity; counting, identifying, and retrieving the description/representation of such dynamical variables is currently an open problem, and a decidedly nontrivial one. In this work we review, via both formal arguments and custom-made examples, the most relevant methods to unveil the gravitational degrees of freedom of a given model, discussing the merits, subtleties and pitfalls of the various approaches.

Higher-order theories of gravity: diagnosis, extraction and reformulation via non-metric extra degrees of freedom-a review.

PubMed

Belenchia, Alessio; Letizia, Marco; Liberati, Stefano; Di Casola, Eolo

2018-03-01

Modifications of Einstein's theory of gravitation have been extensively considered in the past years, in connection to both cosmology and quantum gravity. Higher-curvature and higher-derivative gravity theories constitute the main examples of such modifications. These theories exhibit, in general, more degrees of freedom than those found in standard general relativity; counting, identifying, and retrieving the description/representation of such dynamical variables is currently an open problem, and a decidedly nontrivial one. In this work we review, via both formal arguments and custom-made examples, the most relevant methods to unveil the gravitational degrees of freedom of a given model, discussing the merits, subtleties and pitfalls of the various approaches.

Deferred modification of antiretroviral regimen following documented treatment failure in Asia: results from the TREAT Asia HIV Observational Database (TAHOD)

PubMed Central

Zhou, J; Li, PCK; Kumarasamy, N; Boyd, M; Chen, YMA; Sirisanthana, T; Sungkanuparph, S; Oka, S; Tau, G; Phanuphak, P; Saphonn, V; Zhang, FJ; Omar, SFS; Lee, CKC; Ditangco, R; Merati, TP; Lim, PL; Choi, JY; Law, MG; Pujari, S

2010-01-01

Objective The aim of the study was to examine the rates and predictors of treatment modification following combination antiretroviral therapy (cART) failure in Asian patients with HIV enrolled in the TREAT Asia HIV Observational Database (TAHOD). Methods Treatment failure (immunological, virological and clinical) was defined by World Health Organization criteria. Countries were categorized as high or low income by World Bank criteria. Results Among 2446 patients who initiated cART, 447 were documented to have developed treatment failure over 5697 person-years (7.8 per 100 person-years). A total of 253 patients changed at least one drug after failure (51.6 per 100 person-years). There was no difference between patients from high- and low-income countries [adjusted hazard ratio (HR) 1.02; P = 0.891]. Advanced disease stage [Centers for Disease Control and Prevention (CDC) category C vs. A; adjusted HR 1.38, P = 0.040], a lower CD4 count (≥ 51 cells/μL vs. ≤ 50 cells/μL; adjusted HR 0.61, P = 0.022) and a higher HIV viral load (≥ 400 HIV-1 RNA copies/mL vs. < 400 copies/mL; adjusted HR 2.69, P < 0.001) were associated with a higher rate of treatment modification after failure. Compared with patients from low-income countries, patients from high-income countries were more likely to change two or more drugs (67% vs. 49%; P = 0.009) and to change to a protease-inhibitor-containing regimen (48% vs. 16%; P< 0.001). Conclusions In a cohort of Asian patients with HIV infection, nearly half remained on the failing regimen in the first year following documented treatment failure. This deferred modification is likely to have negative implications for accumulation of drug resistance and response to second-line treatment. There is a need to scale up the availability of second-line regimens and virological monitoring in this region. PMID:19601993

Women's right to health and Ireland's abortion laws.

PubMed

Taylor, Maeve

2015-07-01

The provision of the Irish Constitution that guarantees "the unborn" a right to life equal to that of a pregnant woman has consequences for access to abortion and the care of women in pregnancy generally. Long-awaited legislation to give effect to the narrow constitutional right to abortion was enacted into law in 2013. In 2014, a guidance document for health professionals' implementation of the legislation was published. However, the legislation and guidance document fall far short of international human rights bodies' recommendations: they fail to deliver effective procedural rights to all of the women eligible for lawful abortion within the state and create new legal barriers to women's reproductive rights. At the same time, cases continue to highlight that the Irish Constitution imposes an unethical and rights-violating legal regime in non-abortion-related contexts. Recent developments suggest that both the failure to put guidelines in place and the development of guidelines that are not centered on women or based on rights further reduce women's access to rights and set unacceptable limitations on women's reproductive autonomy. Nevertheless, public and parliamentary scrutiny of cases involving Ireland's abortion laws is increasingly focusing on the need for reform. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Recent Updates to the MELCOR 1.8.2 Code for ITER Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Merrill, Brad J

This report documents recent changes made to the MELCOR 1.8.2 computer code for application to the International Thermonuclear Experimental Reactor (ITER), as required by ITER Task Agreement ITA 81-18. There are four areas of change documented by this report. The first area is the addition to this code of a model for transporting HTO. The second area is the updating of the material oxidation correlations to match those specified in the ITER Safety Analysis Data List (SADL). The third area replaces a modification to an aerosol tranpsort subroutine that specified the nominal aerosol density internally with one that now allowsmore » the user to specify this density through user input. The fourth area corrected an error that existed in an air condensation subroutine of previous versions of this modified MELCOR code. The appendices of this report contain FORTRAN listings of the coding for these modifications.« less

Current Performance Characteristics of NASA Langley Research Center's Cockpit Motion Base and Standardized Test Procedure for Future Performance Characterization

NASA Technical Reports Server (NTRS)

Cowen, Brandon; Stringer, Mary T.; Hutchinson, Brian K.; Davidson, Paul C.; Gupton, Lawrence E.

2014-01-01

This report documents the updated performance characteristics of NASA Langley Research Center's (LaRC) Cockpit Motion Base (CMB) after recent revisions that were made to its inner-loop, feedback control law. The modifications to the control law will be briefly described. The performance of the Cockpit Motion Facility (CMF) will be presented. A short graphical comparison to the previous control law can be found in the appendix of this report. The revised controller will be shown to yield reduced parasitic accelerations with respect to the previous controller. Metrics based on the AGARD Advisory Report No. 144 are used to assess the overall system performance due to its recent control algorithm modification. This report also documents the standardized simulator test procedure which can be used in the future to evaluate potential updates to the control law.

Using geologic structures to constrain constitutive laws not accessible in the laboratory

USGS Publications Warehouse

Nevitt, Johanna; Warren, Jessica M.; Kumamoto, Kathryn M.; Pollard, David D.

2018-01-01

In this essay, we explore a central problem of structural geology today, and in the foreseeable future, which is the determination of constitutive laws governing rock deformation to produce geologic structures. Although laboratory experiments provide much needed data and insights about constitutive laws, these experiments cannot cover the range of conditions and compositions relevant to the formation of geologic structures. We advocate that structural geologists address this limitation by interpreting natural experiments, documented with field and microstructural data, using continuum mechanical models that enable the deduction of constitutive laws. To put this procedure into a historical context, we review the founding of structural geology by James Hutton in the late 18th century, and the seminal contributions to continuum mechanics from Newton to Cauchy that provide the tools to model geologic structures. The procedure is illustrated with two examples drawn from recent and on-going field investigations of crustal and mantle lithologies. We conclude by pointing to future research opportunities that will engage structural geologists in the pursuit of constitutive laws during the 21st century.

Modeling, Simulation, and Measurement of Balanced Antipodal Vivaldi (BAV) Antennas for Fully Polarimetric Forward-Looking Ground-Penetrating Radar (FLGPR) Receive Channels

DTIC Science & Technology

2017-08-01

compared against the current receiver. The focus of the design was to maximize low-frequency performance, particularly below 1.0 GHz. The current...Department of the Army position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an...documents the design , simulation, and measurement of balanced antipodal Vivaldi (BAV) antenna elements for the receive channels of a US Army Research

Space station ECLSS integration analysis: Simplified General Cluster Systems Model, ECLS System Assessment Program enhancements

NASA Technical Reports Server (NTRS)

Ferguson, R. E.

1985-01-01

The data base verification of the ECLS Systems Assessment Program (ESAP) was documented and changes made to enhance the flexibility of the water recovery subsystem simulations are given. All changes which were made to the data base values are described and the software enhancements performed. The refined model documented herein constitutes the submittal of the General Cluster Systems Model. A source listing of the current version of ESAP is provided in Appendix A.

Nitric Oxide-Dependent Posttranslational Modification in Plants: An Update

PubMed Central

Astier, Jeremy; Lindermayr, Christian

2012-01-01

Nitric oxide (NO) has been demonstrated as an essential regulator of several physiological processes in plants. The understanding of the molecular mechanism underlying its critical role constitutes a major field of research. NO can exert its biological function through different ways, such as the modulation of gene expression, the mobilization of second messengers, or interplays with protein kinases. Besides this signaling events, NO can be responsible of the posttranslational modifications (PTM) of target proteins. Several modifications have been identified so far, whereas metal nitrosylation, the tyrosine nitration and the S-nitrosylation can be considered as the main ones. Recent data demonstrate that these PTM are involved in the control of a wide range of physiological processes in plants, such as the plant immune system. However, a great deal of effort is still necessary to pinpoint the role of each PTM in plant physiology. Taken together, these new advances in proteomic research provide a better comprehension of the role of NO in plant signaling. PMID:23203119

MOSFET Electric-Charge Sensor

NASA Technical Reports Server (NTRS)

Robinson, Paul A., Jr.

1988-01-01

Charged-particle probe compact and consumes little power. Proposed modification enables metal oxide/semiconductor field-effect transistor (MOSFET) to act as detector of static electric charges or energetic charged particles. Thickened gate insulation acts as control structure. During measurements metal gate allowed to "float" to potential of charge accumulated in insulation. Stack of modified MOSFET'S constitutes detector of energetic charged particles. Each gate "floats" to potential induced by charged-particle beam penetrating its layer.

The ubiquitin family meets the Fanconi anemia proteins.

PubMed

Renaudin, Xavier; Koch Lerner, Leticia; Menck, Carlos Frederico Martins; Rosselli, Filippo

2016-01-01

Fanconi anaemia (FA) is a hereditary disorder characterized by bone marrow failure, developmental defects, predisposition to cancer and chromosomal abnormalities. FA is caused by biallelic mutations that inactivate genes encoding proteins involved in replication stress-associated DNA damage responses. The 20 FANC proteins identified to date constitute the FANC pathway. A key event in this pathway involves the monoubiquitination of the FANCD2-FANCI heterodimer by the collective action of at least 10 different proteins assembled in the FANC core complex. The FANC core complex-mediated monoubiquitination of FANCD2-FANCI is essential to assemble the heterodimer in subnuclear, chromatin-associated, foci and to regulate the process of DNA repair as well as the rescue of stalled replication forks. Several recent works have demonstrated that the activity of the FANC pathway is linked to several other protein post-translational modifications from the ubiquitin-like family, including SUMO and NEDD8. These modifications are related to DNA damage responses but may also affect other cellular functions potentially related to the clinical phenotypes of the syndrome. This review summarizes the interplay between the ubiquitin and ubiquitin-like proteins and the FANC proteins that constitute a major pathway for the surveillance of the genomic integrity and addresses the implications of their interactions in maintaining genome stability. Copyright © 2016 Elsevier B.V. All rights reserved.

NEA Handbook 2006-2007

ERIC Educational Resources Information Center

National Education Association Research Department, 2007

2007-01-01

The National Education Association (NEA) Handbook is published annually for use by Association officers, national and state staff, members, and other interested leaders in the field of education. The Association's key governance documents--including the Constitution, Bylaws, and Rules, and the Legislative Program, resolutions, policy statements,…

12 CFR 1410.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... particular loan constitutes an independent credit risk and such determination is adequately documented in the... Banking FARM CREDIT SYSTEM INSURANCE CORPORATION PREMIUMS § 1410.2 Definitions. (a) Act means the Farm Credit Act of 1971, as amended. (b) Average principal outstanding means the average annual principal...

16 CFR 1025.12 - Answer.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Pleadings, Form, Execution, Service of Documents § 1025.12 Answer. (a) Time for filing. A respondent shall... an answer within the time provided, unless extended, shall constitute a waiver of the right to appear... and conclusions of law as are just and reasonable under the circumstances. ...

46 CFR 15.705 - Watches.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HOMELAND SECURITY MERCHANT MARINE OFFICERS AND SEAMEN MANNING REQUIREMENTS Limitations and... daily basis does not in itself constitute the establishment of a watch. The minimum safe manning levels specified in a vessel's COI or other safe manning document take into consideration routine maintenance...

Organization Values. Symposium 10. [AHRD Conference, 2001].

ERIC Educational Resources Information Center

2001

This document contains three papers on organizational values. "Understanding the Work Beliefs of Nonprofit Executives through Organizational Stories" (Ava S. Wilensky, Carol D. Hansen) reports on a study during which qualitative interviews featuring a story component established that nonprofit executives constitute a diffuse managerial…

31 CFR 515.543 - Proof of origin.

Code of Federal Regulations, 2010 CFR

2010-07-01

... of goods of Cuban origin are generally not issued unless the applicant submits satisfactory... constitute satisfactory proof varies depending upon the facts of the particular case, it is not possible to... satisfactory proof of origin. Independent corroborating documentary evidence, such as insurance documents...

Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases.

PubMed

Walther, Diego J; Stahlberg, Silke; Vowinckel, Jakob

2011-12-01

Functional protein serotonylation is a newly recognized post-translational modification with the primary biogenic monoamine (PBMA) serotonin (5-HT). This covalent protein modification is catalyzed by transglutaminases (TGs) and, for example, acts in the constitutive activation of small GTPases. Multiple physiological roles have been identified since its description in 2003 and, importantly, deregulated serotonylation was shown in the etiology of bleeding disorders, primary pulmonary hypertension and diabetes. The PBMAs 5-HT, histamine, dopamine, and norepinephrine all act as neurotransmitters in the nervous system and as hormones in non-neuronal tissues, which points out their physiological importance. In analogy to serotonylation we have found that also the other PBMAs act through the TG-catalyzed mechanisms of 'histaminylation', 'dopaminylation' and 'norepinephrinylation'. Therefore, PBMAs deploy a considerable portion of their effects via protein monoaminylation in addition to their canonical receptor-mediated signaling. Here, the implications of these newly identified post-translational modifications are presented and discussed. Furthermore, the potential regulatory roles of protein monoaminylation in small GTPase, heterotrimeric G-protein and lipid signaling, as well as in modulating metabolic enzymes and nuclear processes, are critically assessed. © 2011 The Authors Journal compilation © 2011 FEBS.

Civilizing the 'Barbarian': a critical analysis of behaviour modification programmes in forensic psychiatry settings.

PubMed

Holmes, Dave; Murray, Stuart J

2011-04-01

Drawing on the works of Erving Goffman and Michel Foucault, this article presents part of the results of a qualitative study conducted in a forensic psychiatry setting. For many years, behaviour modification programmes (BMPs) have been subjected to scrutiny and harsh criticism on the part of researchers, clinicians and professional organizations. Nevertheless, BMPs continue to be in vogue in some 'total' institutions, such as psychiatric hospitals and prisons. Discourse analysis of mute evidence available in situ was used to critically look at behaviour modification programmes. Compelling examples of behaviour modification care plans are used to illustrate our critical analysis and to support our claim that BMPs violate both scientific and ethical norms in the name of doing 'what is best' for the patients. We argue that the continued use of BMPs is not only flawed from a scientific perspective, but constitutes an unethical approach to the management of nursing care for mentally ill offenders. Nurse managers need to be aware that BMPs violate ethical standards in nursing. As a consequence, they should overtly question the use of these approaches in psychiatric nursing. © 2011 The Authors. Journal compilation © 2011 Blackwell Publishing Ltd.

The Two Stage Model of Preeclampsia: Variations on the Theme

PubMed Central

Roberts, James M; Hubel, Carl A.

2009-01-01

The Two Stage Model of preeclampsia proposes that a poorly perfused placenta (Stage 1) produces factor(s) leading to the clinical manifestations of preeclampsia (Stage2). Stage 1 is not sufficient to cause the maternal syndrome but interacts with maternal constitutional factors (genetic, behavioral or environmental) to result in Stage 2. Recent information indicates the necessity for modifications of this model. It is apparent that changes relevant to preeclampsia and other implantation disorders can be detected in the first trimester, long before the failed vascular remodeling necessary to reduce placental perfusion. In addition, although the factor(s) released from the placenta has usually been considered a toxin, we suggest that what is released may also be an appropriate signal from the fetal/placental unit to overcome reduced nutrient availability that cannot by tolerated by some women who develop preeclampsia. Further, it is evident that linkage is not likely to be by one factor but several, different for different women. Also although the initial model limited the role of maternal constitutional factors to the genesis of Stage 2, this does not appear to be the case. It is evident that the factors increasing risk for preeclampsia are also associated with abnormal implantation. These several modifications have important implications. An earlier origin for Stage 1, which appears to be recognizable by altered concentrations of placental products, could allow earlier intervention. The possibility of a fetal placental factor increasing nutrient availability could provide novel therapeutic options. Different linkages and preeclampsia subtypes could direct specific preventive treatments for different women while the role of maternal constitutional factors to affect placentation provides targets for prepregnancy therapy. The modified Two Stage Model provides a useful guide towards investigating pathophysiology and guiding therapy. PMID:19070896

Report: Fiscal 2005 and 2004 (restated) Financial Statements for the Pesticide Registration Fund

EPA Pesticide Factsheets

Report #2007-1-00002, January 9, 2007. EPA’s Washington Finance Center recorded adjusting and correcting entries for PRIA collections in the Integrated Financial Management System without adequately documenting the errors, corrections, or modifications.

48 CFR 43.204 - Administration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Administration. 43.204... CONTRACT MODIFICATIONS Change Orders 43.204 Administration. (a) Change order documentation. When change... adjusting the contract delivery schedule. (3) Contracting offices and contract administration offices, as...

48 CFR 43.204 - Administration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Administration. 43.204... CONTRACT MODIFICATIONS Change Orders 43.204 Administration. (a) Change order documentation. When change... adjusting the contract delivery schedule. (3) Contracting offices and contract administration offices, as...

48 CFR 43.204 - Administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Administration. 43.204... CONTRACT MODIFICATIONS Change Orders 43.204 Administration. (a) Change order documentation. When change... adjusting the contract delivery schedule. (3) Contracting offices and contract administration offices, as...

Solar Space and Water Heating for School -- Dallas, Texas

NASA Technical Reports Server (NTRS)

1982-01-01

90 page report gives overview of retrofitted solar space-heating and hot-water system installation for 61-year-old high school. Description, specifications, modifications, plan drawings for roof, three floors, basement, correspondence, and documents are part of report.

TSCA Section 5(a)(3)(C) Determination for Microbial Commercial Activity Notice (MCAN) J-16-0036 -- 0041

EPA Pesticide Factsheets

This document describes EPA's Microbial Commercial Activity Notice (MCAN) review determination under amended TSCA for J-16-0036 -- J-16-0041, biofuel producing modified microorganisms, with chromosomally-borne modifications.

Curriculum guidelines and standards for dental laser education

NASA Astrophysics Data System (ADS)

White, Joel M.; et al.

1993-07-01

The curriculum guidelines for dental laser education were developed through a consensus process with members from dental academia, industry and private practice. This document was developed at a workshop on the development of standards for dental laser education and laser instructor certification held at the University of California, San Francisco on July 25 and 26, 1992. A working draft is currently being circulated among dental laser educators, researchers, practitioners, organized dentistry and members of industry. After further discussion, modification and review, the final document will be widely distributed and updated annually. Any questions concerning the guidelines may be addressed to the authors of this document in care of the organizer. Suggestions for the improvement of this standard and endorsement of this document are invited.

Document Monitor

NASA Technical Reports Server (NTRS)

1988-01-01

The charters of Freedom Monitoring System will periodically assess the physical condition of the U.S. Constitution, Declaration of Independence and Bill of Rights. Although protected in helium filled glass cases, the documents are subject to damage from light vibration and humidity. The photometer is a CCD detector used as the electronic film for the camera system's scanning camera which mechanically scans the document line by line and acquires a series of images, each representing a one square inch portion of the document. Perkin-Elmer Corporation's photometer is capable of detecting changes in contrast, shape or other indicators of degradation with 5 to 10 times the sensitivity of the human eye. A Vicom image processing computer receives the data from the photometer stores it and manipulates it, allowing comparison of electronic images over time to detect changes.

First-Term Reenlistment Quality Study (FITREQUEST).

DTIC Science & Technology

1983-11-01

Nonsupport of Family Trainability Recycled During Initial Unit Inspections Entry Training*I Reports of Survey Resists Authority Retraining 8DE (GRAD...will constitute and chair a SAG to monitor study process. (3) ODCSPER will prepare ad submit DD Porn 1498 and final study documents to WIC. d

Frequency Assignment for Joint Aerial Layer Network High-Capacity Backbone

DTIC Science & Technology

2017-08-11

Department of the Army position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an...performance of the proposed approach. Frequency Assignment, JALN, Resource Allocation, Network Optimization, Performance Evaluation 24 Peng Wang 410-278

7 CFR 246.16 - Distribution of funds.

Code of Federal Regulations, 2010 CFR

2010-01-01

... government purchases, as published by the Bureau of Economic Analysis of the Department of Commerce, for the... State agency's stability, residual and operational adjustment funds shall constitute the State agency's... contiguous states and the District of Columbia when the State agency can document that economic conditions...

The Maryland Commercial Vehicle Information Systems and Networks (CVISN) prototype project plan : making intelligent use of ITS/CVO

DOT National Transportation Integrated Search

1996-05-15

This document constitutes the project plan for the Maryland Commercial Vehicle : Information Systems and Networks Prototype, a project undertaken by the State of : Maryland in partnership with the Federal Highway Administration, the Commonwealth of :...

ALC Rooftop Sensor System

DTIC Science & Technology

2017-10-31

Department of the Army position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an... Interior view of the new sensor box ...................................................... 3 Fig. 4 Interior of original sensor box...7 Fig. 10 Interior of fiber patch panel .................................................................. 7 Fig. 11

Economics of Information in Education. ERIC Digest.

ERIC Educational Resources Information Center

Farid, Mona

This digest on the economics of information in education argues that the production, organization, analysis, evaluation, and dissemination of information in education constitute major economic activities, with associated costs and benefits. The document comprises sections on: the value of information; information as an "economic good";…

48 CFR 970.3501-1 - Sponsoring agreements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Sponsoring agreements. 970... Sponsoring agreements. (a) The contract award document constitutes the sponsoring agreement between the... the purpose and mission of the FFRDC. (c) Other elements of the sponsoring agreement which shall be...

48 CFR 970.3501-1 - Sponsoring agreements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Sponsoring agreements. 970... Sponsoring agreements. (a) The contract award document constitutes the sponsoring agreement between the... the purpose and mission of the FFRDC. (c) Other elements of the sponsoring agreement which shall be...

48 CFR 970.3501-1 - Sponsoring agreements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Sponsoring agreements. 970... Sponsoring agreements. (a) The contract award document constitutes the sponsoring agreement between the... the purpose and mission of the FFRDC. (c) Other elements of the sponsoring agreement which shall be...

76 FR 60755 - Air Cargo Screening; Reopening of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... activities, the disclosure of which would constitute an unwarranted invasion of privacy, reveal trade secrets... secrets, confidential commercial or financial information, or SSI to the public regulatory docket. Please.... TSA will hold documents containing SSI, confidential business information, or trade secrets in a...

Recommendations for Emergency Management Planning for School Facilities.

ERIC Educational Resources Information Center

Texas Education Agency, Austin.

Numerous events, such as hurricanes, floods, and tornadoes, constitute a natural disaster for public schools. Human-caused disasters include hazardous-material emergencies, civil riots, fires, and nuclear accidents. This document contains emergency-management planning guidelines, developed by the Texas Education Agency, to help local school…

32 CFR 9.10 - Other.

Code of Federal Regulations, 2010 CFR

2010-07-01

... MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM § 9.10 Other. This..., enforceable by any party, against the United States, its departments, agencies, or other entities, its... requirement of the United States Constitution. Section and subsection captions in this document are for...

Ink jet printing of silver metallization for photovoltaics

NASA Technical Reports Server (NTRS)

Vest, R. W.

1985-01-01

Progress was made in the continuing development of the ink jet printing system for thick film circuits. The unit being used is a prototype ink jet printer. One of the first tasks completed was the complete documentation of this ink jet printing system as it existed. It was determined that this was an essential step in deciding what modifications were needed to the system and how these modifications would be implemented. Design modification studies were started for electronic, mechanical, and programming aspects of the ystem. The areas needeing improvement were discussed and applicable changes decided upon. Some improvments were completed. Although the general areas needing improving were identified and some changes decided upon, the exact details of how other changes can be implemented are yet been decided.

Questioning the cerebellar doctrine.

PubMed

Galliano, Elisa; De Zeeuw, Chris I

2014-01-01

The basic principles of cerebellar function were originally described by Flourens, Cajal, and Marr/Albus/Ito, and they constitute the pillars of what can be considered to be the classic cerebellar doctrine. In their concepts, the main cerebellar function is to control motor behavior, Purkinje cells are the only cortical neuron receiving and integrating inputs from climbing fiber and mossy-parallel fiber pathways, and plastic modification at the parallel fiber synapses onto Purkinje cells constitutes the substrate of motor learning. Yet, because of recent technical advances and new angles of investigation, all pillars of the cerebellar doctrine now face regular re-examination. In this review, after summarizing the classic concepts and recent disputes, we attempt to synthesize an integrated view and propose a revisited version of the cerebellar doctrine. © 2014 Elsevier B.V. All rights reserved.

A journey to citizenship: constructions of citizenship and identity in the British Citizenship Test.

PubMed

Gray, Debra; Griffin, Christine

2014-06-01

The British Citizenship Test was introduced in 2005 as one of a raft of new procedures aimed at addressing the perceived problems of integration and social cohesion in migrant communities. In this study, we argue that this new citizenship procedure signals a shift in British political discourse about citizenship - particularly, the institutionalization of a common British citizen identity that is intended to draw citizens together in a new form of political/national community. In line with this, we examine the British Citizenship Test from a social psychological perspective to interrogate the ways in which the test constitutes identity, constitutes citizenship, and constitutes citizenship-as-identity. Analysis of the test and its associated documents highlights three ways in which Britishness-as-identity is constituted, that is, as a collective identity, as a superordinate and national identity, and finally as both a destination and a journey. These findings are discussed in terms of their implications for models of citizenship and models of identity. © 2013 The British Psychological Society.

Computer output microfilm (FR80) systems software documentation, volume 2

NASA Technical Reports Server (NTRS)

1975-01-01

The system consists of a series of programs which convert digital data from magnetic tapes into alpha-numeric characters, graphic plots, and imagery that is recorded on the face of a cathode ray tube. A special camera photographs the face of the tube on microfilm for subsequent display on a film reader. The applicable documents which apply to this system are delineated. The functional relationship between the system software, the standard insert routines, and the applications programs is described; all the applications programs are described in detail. Instructions for locating those documents are presented along with test preparations sheets for all baseline and/or program modification acceptance tests.

12 CFR 240.17 - Reservation of authority.

Code of Federal Regulations, 2014 CFR

2014-01-01

..., documentation, or other standards or requirements under this part for a specific retail forex transaction or a class of retail forex transactions if the Board determines that the modification is consistent with safety and soundness and the protection of retail forex customers. ...

Estimating restorable wetland water storage at landscape scales

EPA Science Inventory

Globally, hydrologic modifications such as ditching and subsurface drainage have significantly reduced wetland water storage capacity (i.e., the volume of surface water a wetland can retain) and consequent wetland functions. While wetland area has been well documented across many...

On the Road to Reuse: Residential Demolition Bid Specification Development Tool Report & Factsheet - September 2013

EPA Pesticide Factsheets

The September 2013 EPA Region 5 report and factsheet provide tools to help with waste management plans, waste disposal, handling hazardous materials, and earthwork. The documents also suggest demolition modifications to improve environmental results.

75 FR 9592 - FPL Energy Maine Hydro, LLC; Notice of Intent To Prepare an Environmental Document and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-03

... a probable maximum flood, and modification of the existing earthen embankments for improved slope stability and safety. The proposed remedial measures would not alter the basic footprint of the existing dam...

33 CFR 385.32 - Comprehensive Plan Modification Report

Code of Federal Regulations, 2010 CFR

2010-07-01

... environment; (6) Contain appropriate NEPA documentation to supplement the Programmatic Environmental Impact... the Interior, the Environmental Protection Agency, the Department of Commerce, the Seminole Tribe of Florida, the Miccosukee Tribe of Indians of Florida, the Florida Department of Environmental Protection...

Improved document image segmentation algorithm using multiresolution morphology

NASA Astrophysics Data System (ADS)

Bukhari, Syed Saqib; Shafait, Faisal; Breuel, Thomas M.

2011-01-01

Page segmentation into text and non-text elements is an essential preprocessing step before optical character recognition (OCR) operation. In case of poor segmentation, an OCR classification engine produces garbage characters due to the presence of non-text elements. This paper describes modifications to the text/non-text segmentation algorithm presented by Bloomberg,1 which is also available in his open-source Leptonica library.2The modifications result in significant improvements and achieved better segmentation accuracy than the original algorithm for UW-III, UNLV, ICDAR 2009 page segmentation competition test images and circuit diagram datasets.

Fifteen-foot diameter modular space station Kennedy Space Center launch site support definition (space station program Phase B extension definition)

NASA Technical Reports Server (NTRS)

Bjorn, L. C.; Martin, M. L.; Murphy, C. W.; Niebla, J. F., V

1971-01-01

This document defines the facilities, equipment, and operational plans required to support the MSS Program at KSC. Included is an analysis of KSC operations, a definition of flow plans, facility utilization and modifications, test plans and concepts, activation, and tradeoff studies. Existing GSE and facilities that have a potential utilization are identified, and new items are defined where possible. The study concludes that the existing facilities are suitable for use in the space station program without major modification from the Saturn-Apollo configuration.

Graphic/symbol segmentation for Group 4 facsimile systems

NASA Astrophysics Data System (ADS)

Deutermann, A. R.

1982-04-01

The purpose of this study was to examine possible techniques for and symbol areas, and assemble a code that represents the entire document. Parameters to be considered include compression, commonality with facsimile and TELETEX* transmissions, and complexity of implementation. Six segmentation technique were selected for analysis. The techniques were designed to differ from each other as much as possible, so as to display a wide variety of characteristics. For each technique, many minor modifications would be possible, but it is not expected that these modifications would alter the conclusions drawn from the study.

Optical trapping/modification of nano-(micro)particles by gradient and photorefractive forces during laser illumination

NASA Astrophysics Data System (ADS)

Kukhtarev, N.; Kukhtareva, T.; Okafor, F.

2010-08-01

In this paper we describe photo-induced trapping/redistribution of silver nano-(micro) particles near the surface of photorefractive crystal LiNbO3:Fe. This type of optical trapping is due to combined forces of direct gradient-force trapping and asymmetric photorefractive forces of electro-phoresis and dielectro-phoresis. The silver nanoparticles were produced through extracellular biosynthesis on exposure to the fungus, Fusarium oxysporum (FO) and to the plant extracts. Pulsed and CW visible laser radiation lead to significant modification of nanoparticle clusters. This study indicates that extracellular biosynthesis can constitute a possible viable alternative method for the production of nanoparticles. In addition, the theoretical modeling of asymmetric photorefractive electric field grating has been presented and compared with the experimental results.

Development of a Constitutive Equation for HSLA (High-Strength Low- Alloy)-100 at Cryogenic Temperatures

DTIC Science & Technology

1987-12-01

temperatur The Holloncn Power Equation and the VocE. Equation are used tý) describe the true stress;’true strain behavior to failure of individual tests...Hollomon Power Equation (a= Kcn) and the Voce Equation (c=G -[O -ao1exp[-E!A]) are used to describe the true stress / true strain behavior to failure of...6 8 A. MODIFICATIONS/ IMPROVEMENTS IN THE USE OF THE VOCE

Evidence for Coordination and Redox Changes of Iron in Shocked Feldspar from Synchrotron MicroXANES

NASA Technical Reports Server (NTRS)

Delaney, J. S.; Dyar, M. D.; Hoerz, F.; Johnson, J. R.

2003-01-01

Shock modification of feldspar has been documented and experimentally reproduced in many studies since the recognition of maskelynite in Shergotty. Experimentally shocked feldspar samples have been well studied using chemical and crystallographic techniques. The crystallographic, site-specific characterization of major and minor elements is less well documented. We present early x-ray absorption (XAS) spectral data for a suite of albitite samples that were experimentally shocked at pressures between 17 and 50 Gpa.

Characterization of Steroid Receptor RNA Activator Protein Function in Modulating the Estrogen Signaling Pathway

DTIC Science & Technology

2008-03-01

official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form...control). Four experiments were performed and the average modifications calculated). A significant (pɘ.05, Student’s t- test ) average increase of 90% in...assessed by TP-PCR at t: 24 h, 48 h, and 72h. We found a significant increase (2.5 fold, pɘ.05, Student’s t- test ) in relative intron-1 retention was

Data Gap Analysis and Database Expansion of Parameters for Munitions Constitutents

DTIC Science & Technology

2005-12-01

BIOWIN documentation (Boethling et al. 1994). Sediment is briefly considered to be anaerobic soil, with overall conversion factors, and water is aerobic...degradation of a chemical in water, soil, and sediment is determined using the ultimate biodegradation expert survey module of the BIOWIN estimation

Combustibility determination for cotton gin dust and almond huller dust

USDA-ARS?s Scientific Manuscript database

It has been documented that some dusts generated while processing agricultural products, such as grain and sugar (OSHA, 2009), can constitute combustible dust hazards. After a catastrophic dust explosion in a sugar refinery in 2008, OSHA initiated action to develop a mandatory standard to comprehen...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

14 CFR 399.3 - Statements in other Board documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Section 399.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION..., order, certificate, permit, exemption, or waiver shall be considered a statement of policy within the meaning of this part, even though such statements may constitute a precedent in future cases or declare...

5 CFR 293.403 - Contents of employee performance files.

Code of Federal Regulations, 2011 CFR

2011-01-01

... REGULATIONS PERSONNEL RECORDS Employee Performance File System Records § 293.403 Contents of employee performance files. (a) A decision on what constitutes a performance-related document within the meaning of... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Contents of employee performance files...

5 CFR 293.403 - Contents of employee performance files.

Code of Federal Regulations, 2013 CFR

2013-01-01

... REGULATIONS PERSONNEL RECORDS Employee Performance File System Records § 293.403 Contents of employee performance files. (a) A decision on what constitutes a performance-related document within the meaning of... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Contents of employee performance files...

5 CFR 293.403 - Contents of employee performance files.

Code of Federal Regulations, 2014 CFR

2014-01-01

... REGULATIONS PERSONNEL RECORDS Employee Performance File System Records § 293.403 Contents of employee performance files. (a) A decision on what constitutes a performance-related document within the meaning of... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Contents of employee performance files...

5 CFR 293.403 - Contents of employee performance files.

Code of Federal Regulations, 2012 CFR

2012-01-01

... REGULATIONS PERSONNEL RECORDS Employee Performance File System Records § 293.403 Contents of employee performance files. (a) A decision on what constitutes a performance-related document within the meaning of... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Contents of employee performance files...

Vocal specialization through tracheal elongation in an extinct Miocene pheasant from China.

PubMed

Li, Zhiheng; Clarke, Julia A; Eliason, Chad M; Stidham, Thomas A; Deng, Tao; Zhou, Zhonghe

2018-05-25

Modifications to the upper vocal tract involving hyper-elongated tracheae have evolved many times within crown birds, and their evolution has been linked to a 'size exaggeration' hypothesis in acoustic signaling and communication, whereby smaller-sized birds can produce louder sounds. A fossil skeleton of a new extinct species of wildfowl (Galliformes: Phasianidae) from the late Miocene of China, preserves an elongated, coiled trachea that represents the oldest fossil record of this vocal modification in birds and the first documentation of its evolution within pheasants. The phylogenetic position of this species within Phasianidae has not been fully resolved, but appears to document a separate independent origination of this vocal modification within Galliformes. The fossil preserves a coiled section of the trachea and other remains supporting a tracheal length longer than the bird's body. This extinct species likely produced vocalizations with a lower fundamental frequency and reduced harmonics compared to similarly-sized pheasants. The independent evolution of this vocal feature in galliforms living in both open and closed habitats does not appear to be correlated with other factors of biology or its open savanna-like habitat. Features present in the fossil that are typically associated with sexual dimorphism suggest that sexual selection may have resulted in the evolution of both the morphology and vocalization mechanism in this extinct species.

Geochemical Data for Upper Mineral Creek, Colorado, Under Existing Ambient Conditions and During an Experimental pH Modification, August 2005

USGS Publications Warehouse

Runkel, Robert L.; Kimball, Briant A.; Steiger, Judy I.; Walton-Day, Katherine

2009-01-01

Mineral Creek, an acid mine drainage stream in south-western Colorado, was the subject of a water-quality study that employed a paired synoptic approach. Under the paired synoptic approach, two synoptic sampling campaigns were conducted on the same study reach. The initial synoptic campaign, conducted August 22, 2005, documented stream-water quality under existing ambient conditions. A second synoptic campaign, conducted August 24, 2005, documented stream-water quality during a pH-modification experiment that elevated the pH of Mineral Creek. The experimental pH modification was designed to determine the potential reductions in dissolved constituent concentrations that would result from the implementation of an active treatment system for acid mine drainage. During both synoptic sampling campaigns, a solution containing lithium bromide was injected continuously to allow for the calculation of streamflow using the tracer-dilution method. Synoptic water-quality samples were collected from 30 stream sites and 11 inflow locations along the 2-kilometer study reach. Data from the study provide spatial profiles of pH, concentration, and streamflow under both existing and experimentally-altered conditions. This report presents the data obtained August 21-24, 2005, as well as the methods used for sample collection and data analysis.

Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks.

PubMed

Heinz, Kathrin S; Casas-Delucchi, Corella S; Török, Timea; Cmarko, Dusan; Rapp, Alexander; Raska, Ivan; Cardoso, M Cristina

2018-05-10

The replication of the genome is a highly organized process, both spatially and temporally. Although a lot is known on the composition of the basic replication machinery, how its activity is regulated is mostly unknown. Several chromatin properties have been proposed as regulators, but a potential role of the nuclear DNA position remains unclear. We made use of the prominent structure and well-defined heterochromatic landscape of mouse pericentric chromosome domains as a well-studied example of late replicating constitutive heterochromatin. We established a method to manipulate its nuclear position and evaluated the effect on replication timing, DNA compaction and epigenetic composition. Using time-lapse microscopy, we observed that constitutive heterochromatin, known to replicate during late S-phase, was replicated in mid S-phase when repositioned to the nuclear periphery. Out-of-schedule replication resulted in deficient post-replicative maintenance of chromatin modifications, namely silencing marks. We propose that repositioned constitutive heterochromatin was activated in trans according to the domino model of origin firing by nearby (mid S) firing origins. In summary, our data provide, on the one hand, a novel approach to manipulate nuclear DNA position and, on the other hand, establish nuclear DNA position as a novel mechanism regulating DNA replication timing and epigenetic maintenance.

Consolidated Development Objectives Document (CDOD) For MB-60

NASA Technical Reports Server (NTRS)

Greene, William D.

2013-01-01

This document defines the objectives related to liquid rocket engine system development to be undertaken by JAXA in support of the Space Launch System (SLS) Program managed out of the NASA Marshall Space Flight Center (MSFC). These objectives include furnishing the necessary management, labor, facilities, tools, equipment, and materials required to execute the specified activities. 1.1 Project Scope: The scope of this effort is to develop a rocket engine and associated products per the objectives and technical requirements established in this document. This engine, minus the engine controller, designated here as MB ]60, is to be developed through to a prequalification point of maturity. It is assumed that should JCNE ]1 development proceed beyond this maturity point towards actual flight qualification, the engine controller will be supplied and integrated by NASA. 1.2 Document Structure: The structure of this Consolidated Development Objectives Document (CDOD) includes a traditional description of objectives in a SOO, plus the associated Data Products Document (DPD) in an attached appendix, and then Engine Requirements Document (ERD) as another attached appendix. It is the intent that this document, in conjunction with the cited applicable documents, should constitute a complete programmatic and technical description of the development effort to be pursued.

Quality assurance software inspections at NASA Ames: Metrics for feedback and modification

NASA Technical Reports Server (NTRS)

Wenneson, G.

1985-01-01

Software inspections are a set of formal technical review procedures held at selected key points during software development in order to find defects in software documents--is described in terms of history, participants, tools, procedures, statistics, and database analysis.

10 CFR 70.72 - Facility changes and change process.

Code of Federal Regulations, 2010 CFR

2010-01-01

... management system to evaluate, implement, and track each change to the site, structures, processes, systems, equipment, components, computer programs, and activities of personnel. This system must be documented in... licensed material; (3) Modifications to existing operating procedures including any necessary training or...

10 CFR 70.72 - Facility changes and change process.

Code of Federal Regulations, 2011 CFR

2011-01-01

... management system to evaluate, implement, and track each change to the site, structures, processes, systems, equipment, components, computer programs, and activities of personnel. This system must be documented in... licensed material; (3) Modifications to existing operating procedures including any necessary training or...

10 CFR 70.72 - Facility changes and change process.

Code of Federal Regulations, 2012 CFR

2012-01-01

... management system to evaluate, implement, and track each change to the site, structures, processes, systems, equipment, components, computer programs, and activities of personnel. This system must be documented in... licensed material; (3) Modifications to existing operating procedures including any necessary training or...

10 CFR 70.72 - Facility changes and change process.

Code of Federal Regulations, 2014 CFR

2014-01-01

... management system to evaluate, implement, and track each change to the site, structures, processes, systems, equipment, components, computer programs, and activities of personnel. This system must be documented in... licensed material; (3) Modifications to existing operating procedures including any necessary training or...

10 CFR 70.72 - Facility changes and change process.

Code of Federal Regulations, 2013 CFR

2013-01-01

... management system to evaluate, implement, and track each change to the site, structures, processes, systems, equipment, components, computer programs, and activities of personnel. This system must be documented in... licensed material; (3) Modifications to existing operating procedures including any necessary training or...

Contemporary and restorable wetland water storage: A landscape perspective

USDA-ARS?s Scientific Manuscript database

Surface water storage in wetlands drives ecosystem function from local to landscape scales. In many regions, hydrologic modifications have significantly reduced wetland storage capacity and subsequently diminished wetland functions. While the loss of wetland area has been well documented across many...

76 FR 69274 - Draft Guidance for Industry and Food and Drug Administration Staff; 510(k) Device Modifications...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-08

... for Devices and Radiological Health (CDRH) guidance documents is available at http://www.fda.gov...'' from CDRH, you may either send an email request to [email protected] to receive an electronic copy of...

48 CFR 307.7101 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PLANNING ACQUISITION PLANNING Acquisition Plan 307.7101 Policy. (a) An AP is required for all acquisitions... GWAC; or (ii) A BPA, provided there is an approved acquisition planning document for the original... under HHS-wide strategic sourcing vehicles. (8) Contract/order modifications that— (i) Exercise options...

Seventeenth-century experimenta, magisterial formulae and the ‘animal alkahest’: new documents found in Royal Society archives

PubMed Central

Alfonso-Goldfarb, Ana Maria; Ferraz, Márcia Helena Mendes; Rattansi, Piyo M.

2015-01-01

In this paper we present three newly rediscovered documents from the Royal Society archives that, together with the four described in our previous publications, constitute a set on a cognate theme. The documents were written by, or addressed to, members of the early Royal Society, and their subject is several magisterial formulae, including J. B. van Helmont's alkahest and Ludus. In addition to the interest in those formulae as medicines for various grave illnesses, our analysis showed that some seventeenth-century scholars sought to explain operations of the animal body by invoking similar but natural substances, while attempting to assimilate the latest anatomical discoveries into a novel framework. The complete set of documents sheds some new light on the interests of seventeenth-century networks of scholars concerned with experimenta. PMID:26665488

Solid waste information and tracking system client-server conversion project management plan

DOE Office of Scientific and Technical Information (OSTI.GOV)

May, D.L.

1998-04-15

This Project Management Plan is the lead planning document governing the proposed conversion of the Solid Waste Information and Tracking System (SWITS) to a client-server architecture. This plan presents the content specified by American National Standards Institute (ANSI)/Institute of Electrical and Electronics Engineers (IEEE) standards for software development, with additional information categories deemed to be necessary to describe the conversion fully. This plan is a living document that will be reviewed on a periodic basis and revised when necessary to reflect changes in baseline design concepts and schedules. This PMP describes the background, planning and management of the SWITS conversion.more » It does not constitute a statement of product requirements. Requirements and specification documentation needed for the SWITS conversion will be released as supporting documents.« less

26 CFR 1.6038A-3 - Record maintenance.

Code of Federal Regulations, 2011 CFR

2011-04-01

... control RC and the two corporations do not constitute a group of “controlled taxpayers” for purposes of... party does not control. Functional equivalents of the specified documents are acceptable. Record.... If, however, on audit it is determined that F does control RC, all records relevant to determining...

26 CFR 1.6038A-3 - Record maintenance.

Code of Federal Regulations, 2014 CFR

2014-04-01

... control RC and the two corporations do not constitute a group of “controlled taxpayers” for purposes of... party does not control. Functional equivalents of the specified documents are acceptable. Record.... If, however, on audit it is determined that F does control RC, all records relevant to determining...

Humidity Effects on Soluble Core Mechanical and Thermal Properties (Polyvinyl Alcohol/Microballoon Composite)

NASA Technical Reports Server (NTRS)

1993-01-01

This document constitutes the final report for the study of humidity effects and loading rate on soluble core (PVA/MB composite material) mechanical and thermal properties. This report describes test results, procedures employed, and any unusual occurrences or specific observations associated with this test program.

78 FR 8351 - Delegation of a Reporting Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 78, No. 25 / Wednesday... as President by the Constitution and the laws of the United States, including section 301 of title 3... congressional committees and publish this memorandum in the Federal Register. (Presidential Sig.) THE WHITE...

La estadistica en el planeamiento educativo (Statistics in Educational Planning).

ERIC Educational Resources Information Center

Leon Pacheco, Tomas

1971-01-01

This document is an English-language abstract (approximately 1500 words) summarizing the author's definitions of the principal physical and human characteristics of elementary and secondary education as presently constituted in Mexico so that school personnel may comply with Mexican regulations that force them to supply educational statistics. For…

Graciela Camina a la Escuela (Graciela Walks to School).

ERIC Educational Resources Information Center

Stewart, Julieta

Rules of traffic safety constitute the theme of this booklet, intended as reading material for Spanish speaking elementary school children. The document was developed by students in the Bilingual Teacher Aide Program at Mesa Community College. Both the Spanish language and content have been controlled to provide linguistically and culturally…

Religious Involvement and Depressive Symptoms among Mexican-Origin Adults in California

ERIC Educational Resources Information Center

Ellison, Christopher G.; Finch, Brian K.; Ryan, Daniell Nicole; Salinas, Jennifer J.

2009-01-01

A burgeoning literature has documented generally salutary relationships between various aspects of religious involvement and mental health outcomes, including depressive symptoms. However, few of these studies have focused on Latinos (Hispanics), who now constitute the largest ethnic minority population in the United States. Our work addresses…

The Recruitment, Channeling, and Placement of Chicano Teachers.

ERIC Educational Resources Information Center

Chacon, Gloria, Ed.; Bowman, James, Ed.

Chapter 4 of the U.S. Commission on Civil Rights publication entitled "Toward Quality Education for Mexican Americans" constitutes the first part of this two-part document which examines the recruitment, channeling, and counselling of Mexican American teachers in the Southwest. Specific areas examined in this chapter include: (1)…

75 FR 1538 - Airworthiness Directives; Airbus (Type Certificate Previously Held by Airbus Industrie) Model...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-12

... AIRBUS A340 ALS [Airworthiness Limitations Section] Part 3: --adds new CMR (Certification Maintenance... ALS Part 3 constitutes an unsafe condition. * * * * * The unsafe condition is a safety-significant... Airworthiness Limitations Section (ALS) Part 3. The content of the CMR Document has been recently transferred...

Educational Engagement Practices of Urban Immigrant Latina Mothers

ERIC Educational Resources Information Center

Greenberg, Joy Pastan

2012-01-01

Although numerous studies have documented the positive association between parental involvement in children's education and a range of academic and motivational outcomes, less work has focused on the Latino immigrant population. Yet, Latino students constitute the fastest-growing ethnic group in the United States. This study examines the…

48 CFR 33.104 - Protests to GAO.

Code of Federal Regulations, 2010 CFR

2010-10-01

... competitive advantage; and (B) Protester's documents which the agency determines, pursuant to law or... business concern within the meaning of section 3(a) of the Small Business Act (see 2.101, “Small business..., other than small businesses, constitutes a benchmark as to a “reasonable” level for attorney's fees for...

Moral Education and Public Schools: Evolution in 19th Century Wisconsin.

ERIC Educational Resources Information Center

Hunt, Thomas C.

As evidenced by official documents of state superintendents, Protestantism and Bible-reading ceased to comprise the foundation for moral education in the public schools of Wisconsin by 1890. Although the 1848 Wisconsin Constitution mandated against sectarian instruction in public schools, the "Annual Reports" and "Decision…

76 FR 52561 - Timely Mailing Treated as Timely Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

... to the only ways to establish prima facie evidence of delivery of documents that have a filing... (PDS) designated under criteria established by the IRS, will constitute prima facie evidence of... taxpayers to be able to establish the postmark date and prima facie evidence of delivery when using...

A New Program for Married Students.

ERIC Educational Resources Information Center

Moore, Marv; Hinkle, John E.

The lack of attention to the student marriage relationship and its impact is documented and guidelines for an outreach program involving married students are presented. Objectives of such a program include: (1) to study student marriages and define more clearly the psychological variables that constitute a growing, healthy marriage, and (2) to…

Perspectives: Readings on Contemporary American Government.

ERIC Educational Resources Information Center

Close Up Foundation, Arlington, VA.

This document is composed of readings and activities concerning the government of the United States. The main topics addressed are: the Constitution, the Presidency, the Congress, the Judiciary, the bureaucracy, interest groups, the media, and the people. Each section begins with an introductory reading, followed by essays from prominent citizens…

78 FR 33349 - Certain Frozen Warmwater Shrimp From Indonesia: Negative Preliminary Countervailing Duty...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-04

... CONTACT: Gene Calvert, Jun Jack Zhao, or Emily Halle, AD/CVD Operations, Import Administration, International Trade Administration, U.S. Department of Commerce, 14th Street and Constitution Avenue NW... Preliminary Decision Memorandum is a public document and is on file electronically via Import Administration's...

Bring the Constitution Back in

ERIC Educational Resources Information Center

Johnson, K. C.

2012-01-01

In this article, the author talks about the report "A Crucible Moment: College Learning & Democracy's Future," which provides a blueprint of what higher education ought "not" to do. The document was produced by the Association of American Colleges & Universities (AAC&U), an organization with a long history not only of demanding the advancement of…

Teaching Strategy: Comparing Rights Documents.

ERIC Educational Resources Information Center

Shiman, David A.

1998-01-01

Engages students in comparing the rights proclaimed in the Universal Declaration of Human Rights (UDHR) with those present in the United States Bill of Rights and other constitutional amendments. Challenges the students to explore reasons for the presence or absence of certain rights and to reflect on the role of the government. (CMK)

Chinese-Cantonese (Toishan) Basic Course.

ERIC Educational Resources Information Center

Defense Language Inst., Washington, DC.

This seven-volume series constitutes the Defense Language Institute (Army Language School) 47-week course in the Toishan dialect of Cantonese. Beginning lessons present the tone and sound system in romanized script. Chinese characters are introduced in the fourth lesson. (See related document AL 001 479, "Chinese Cantonese Basic Course,"…

A Community College President--What's That? Forum 45.

ERIC Educational Resources Information Center

Cosand, Joseph P.; And Others

This document compiles the Forum 45 major address and the responses of three reactors. Dr. Cosand's paper seeks to define what constitutes a top quality community college president. There are many styles of presidential leadership; however, the possibility of a president's providing strong and enlightened leadership depends on his effectiveness in…

Alternative Options in State-University Relationships in a Regional Setting: The Case of Canada.

ERIC Educational Resources Information Center

Farquhar, Robin H.

This document highlights the special challenges that Canada's higher education system faces due to its organizational structure that is, the relationship between the federal government and the provincial governments. Virtually all Canadian universities are publicly supported, but because the constitution clearly assigns responsibility for…

First Steps in the Journey from Consumers to Producers of Research in Deaf Education

ERIC Educational Resources Information Center

Gardiner-Walsh, Stephanie; Kemmery, Megan; Compton, Mary V.

2014-01-01

Faculty Shortages in the study of low-incidence sensory disabilities (deafness, blindness, deaf-blindness) constitute personnel preparation challenges, as documented by a variety of organizations. To alleviate this deficit in the low-incidence sensory disability professoriat, the National Leadership Consortium for Sensory Disabilities (NLCSD) was…

Deoxyribonucleic acid restriction and modification systems in Salmonella: chromosomally located systems of different serotypes.

PubMed Central

Bullas, L R; Colson, C; Neufeld, B

1980-01-01

With the use of four different phages, Salmonella strains representing 85 different serotypes were examined to determine their restriction-modification phenotype. They fell into one of three groups on this basis: group 1, those which lacked the common LT system; group 2, those in which only the LT system could be recognized; and group 3. those which possessed the LT system and at least one other system shown with some serotypes to be closely linked to serB. The specificity of the serB-linked restriction-modification system was unique for each serotype, but different strains of the same serotype expressed the same specificity. Two of the systems were shown to behave in genetic crosses as functional alleles of the S. typhimurium SB system. It is possible that these serB-linked restriction-modification systems constitute a large multiallelic series of genes extending throughout the Salmonella genus and Escherichia coli. We suggest that the division of the Salmonella into the three restriction-modification groups may be significant in defining a "biological grouping" of the different serotypes within the genus which may ultimately be useful in describing the Salmonella species. From the genetic relatedness between the genes of some of the Salmonella restriction-modification systems with those of the E. coli systems, we deduce that the restriction endonuclases produced by the Salmonella serB-linked systems are of type 1. Determination of the nucleotide sequences of the recognition sites of the restriction endonucleases of selected Salmonella systems should further our understanding of specificity with these enzymes. PMID:6243623

Topex Microwave Radiometer thermal control - Post-system-test modifications and on-orbit performance

NASA Technical Reports Server (NTRS)

Lin, Edward I.

1993-01-01

The Topex Microwave Radiometer has had an excellent thermal performance since launch. The instrument, however, went through a hardware modification right before launch to correct for a thermal design inadequacy that was uncovered during the spacecraft thermal vacuum test. This paper reports on how the initially obscure problem was tracked down, and how the thermal models were revised, validated, and utilized to investigate the solution options and guide the hardware modification decisions. Details related to test data interpretation, analytical uncertainties, and model-prediction vs. test-data correlation, are documented. Instrument/spacecraft interface issues, where the problem originated and where in general pitfalls abound, are dealt with specifically. Finally, on-orbit thermal performance data are presented, which exhibit good agreement with flight predictions, and lessons learned are discussed.

Development of mix design procedures for gap-graded asphalt-rubber asphalt concrete

DOT National Transportation Integrated Search

2007-11-01

A research project was conducted to identify and document current modifications to ARIZONA 815c (75-blow Marshall method) used to develop gap-graded asphalt rubber asphalt concrete (GG AR AC) mix designs, and to develop and test improvements to provi...

76 FR 37034 - Proposed Modification of the Las Vegas, NV, Class B Airspace Area; Public Meetings; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... Tuesday, August 23, 2011, in Henderson, NV. Also, the document contained the wrong phone number for the... number (2) in the ADDRESSES caption to read: ADDRESSES: (2) The meeting on Tuesday, August 23, 2011, will...

48 CFR 801.602-81 - Documents required for business clearance reviews.

Code of Federal Regulations, 2010 CFR

2010-10-01

... business clearance reviews. 801.602-81 Section 801.602-81 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career... reviews. When a bid or offer, proposed contract modification, or proposed lease requires a business...

Structural disorder of graphite and implications for graphite thermometry

NASA Astrophysics Data System (ADS)

Kirilova, Martina; Toy, Virginia; Rooney, Jeremy S.; Giorgetti, Carolina; Gordon, Keith C.; Collettini, Cristiano; Takeshita, Toru

2018-02-01

Graphitization, or the progressive maturation of carbonaceous material, is considered an irreversible process. Thus, the degree of graphite crystallinity, or its structural order, has been calibrated as an indicator of the peak metamorphic temperatures experienced by the host rocks. However, discrepancies between temperatures indicated by graphite crystallinity versus other thermometers have been documented in deformed rocks. To examine the possibility of mechanical modifications of graphite structure and the potential impacts on graphite thermometry, we performed laboratory deformation experiments. We sheared highly crystalline graphite powder at normal stresses of 5 and 25 megapascal (MPa) and aseismic velocities of 1, 10 and 100 µm s-1. The degree of structural order both in the starting and resulting materials was analyzed by Raman microspectroscopy. Our results demonstrate structural disorder of graphite, manifested as changes in the Raman spectra. Microstructural observations show that brittle processes caused the documented mechanical modifications of the aggregate graphite crystallinity. We conclude that the calibrated graphite thermometer is ambiguous in active tectonic settings.

Post-Translational Modification of Constitutive Nitric Oxide Synthase in the Penis

PubMed Central

Musicki, Biljana; Ross, Ashley E.; Champion, Hunter C.; Burnett, Arthur L.; Bivalacqua, Trinity J.

2009-01-01

Erectile dysfunction (ED) is a common men's health problem characterized by the consistent inability to sustain an erection sufficient for sexual intercourse. Basic science research on erectile physiology has been devoted to investigating the pathogenesis of ED and has led to the conclusion that ED is predominately a disease of vascular origin and/or neurogenic dysfunction. The constitutive forms of nitric oxide synthase [NOS; endothelial NOS (eNOS) and neuronal NOS (nNOS)] are important enzymes involved in the production of nitric oxide (NO) and thus regulate penile vascular homeostasis. Given the impact of endothelial- and neuronal-derived NO in penile vascular biology, a great deal of research over the past decade has focused on the role of NO synthesis from the endothelium and nitrergic nerve terminal in normal erectile physiology as well as in disease states. Loss of the functional integrity of the endothelium and subsequent endothelial dysfunction plays an integral role in the occurrence of ED. Therefore, molecular mechanisms involved in dysregulation of these NOS isoforms in the development of ED are essential to discovering the pathogenesis of ED in various disease states. This communication reviews the role of eNOS and nNOS in erectile physiology and discusses the alterations in eNOS and nNOS via post-translation modification in various vascular diseases of the penis. PMID:19342700

Epigenetic treatment of pancreatic cancer: is there a therapeutic perspective on the horizon?

PubMed

Hessmann, Elisabeth; Johnsen, Steven A; Siveke, Jens T; Ellenrieder, Volker

2017-01-01

Pancreatic ductal adenocarcinoma (PDAC) constitutes one of the most aggressive malignancies with a 5-year survival rate of <7%. Due to growing incidence, late diagnosis and insufficient treatment options, PDAC is predicted to soon become one of the leading causes of cancer-related death. Although intensified cytostatic combinations, particularly gemcitabine plus nab-paclitaxel and the folinic acid, fluorouracil, irinotecan, oxaliplatin (FOLFIRINOX) protocol, provide some improvement in efficacy and survival compared with gemcitabine alone, a breakthrough in the treatment of metastatic pancreatic cancer remains out of sight. Nevertheless, recent translational research activities propose that either modulation of the immune response or pharmacological targeting of epigenetic modifications alone, or in combination with chemotherapy, might open highly powerful therapeutic avenues in GI cancer entities, including pancreatic cancer. Deregulation of key epigenetic factors and chromatin-modifying proteins, particularly those responsible for the addition, removal or recognition of post-translational histone modifications, are frequently found in human pancreatic cancer and hence constitute particularly exciting treatment opportunities. This review summarises both current clinical trial activities and discovery programmes initiated throughout the biopharma landscape, and critically discusses the chances, hurdles and limitations of epigenetic-based therapy in future PDAC treatment. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

MPS Solidification Model. Volume 2: Operating guide and software documentation for the unsteady model

NASA Technical Reports Server (NTRS)

Maples, A. L.

1981-01-01

The operation of solidification Model 2 is described and documentation of the software associated with the model is provided. Model 2 calculates the macrosegregation in a rectangular ingot of a binary alloy as a result of unsteady horizontal axisymmetric bidirectional solidification. The solidification program allows interactive modification of calculation parameters as well as selection of graphical and tabular output. In batch mode, parameter values are input in card image form and output consists of printed tables of solidification functions. The operational aspects of Model 2 that differ substantially from Model 1 are described. The global flow diagrams and data structures of Model 2 are included. The primary program documentation is the code itself.

RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response

PubMed Central

Maréchal, Alexandre; Zou, Lee

2015-01-01

The Replication Protein A (RPA) complex is an essential regulator of eukaryotic DNA metabolism. RPA avidly binds to single-stranded DNA (ssDNA) through multiple oligonucleotide/oligosaccharide-binding folds and coordinates the recruitment and exchange of genome maintenance factors to regulate DNA replication, recombination and repair. The RPA-ssDNA platform also constitutes a key physiological signal which activates the master ATR kinase to protect and repair stalled or collapsed replication forks during replication stress. In recent years, the RPA complex has emerged as a key target and an important regulator of post-translational modifications in response to DNA damage, which is critical for its genome guardian functions. Phosphorylation and SUMOylation of the RPA complex, and more recently RPA-regulated ubiquitination, have all been shown to control specific aspects of DNA damage signaling and repair by modulating the interactions between RPA and its partners. Here, we review our current understanding of the critical functions of the RPA-ssDNA platform in the maintenance of genome stability and its regulation through an elaborate network of covalent modifications. PMID:25403473

RPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage response.

PubMed

Maréchal, Alexandre; Zou, Lee

2015-01-01

The Replication Protein A (RPA) complex is an essential regulator of eukaryotic DNA metabolism. RPA avidly binds to single-stranded DNA (ssDNA) through multiple oligonucleotide/oligosaccharide-binding folds and coordinates the recruitment and exchange of genome maintenance factors to regulate DNA replication, recombination and repair. The RPA-ssDNA platform also constitutes a key physiological signal which activates the master ATR kinase to protect and repair stalled or collapsed replication forks during replication stress. In recent years, the RPA complex has emerged as a key target and an important regulator of post-translational modifications in response to DNA damage, which is critical for its genome guardian functions. Phosphorylation and SUMOylation of the RPA complex, and more recently RPA-regulated ubiquitination, have all been shown to control specific aspects of DNA damage signaling and repair by modulating the interactions between RPA and its partners. Here, we review our current understanding of the critical functions of the RPA-ssDNA platform in the maintenance of genome stability and its regulation through an elaborate network of covalent modifications.

Documentation of a deep percolation model for estimating ground-water recharge

USGS Publications Warehouse

Bauer, H.H.; Vaccaro, J.J.

1987-01-01

A deep percolation model, which operates on a daily basis, was developed to estimate long-term average groundwater recharge from precipitation. It has been designed primarily to simulate recharge in large areas with variable weather, soils, and land uses, but it can also be used at any scale. The physical and mathematical concepts of the deep percolation model, its subroutines and data requirements, and input data sequence and formats are documented. The physical processes simulated are soil moisture accumulation, evaporation from bare soil, plant transpiration, surface water runoff, snow accumulation and melt, and accumulation and evaporation of intercepted precipitation. The minimum data sets for the operation of the model are daily values of precipitation and maximum and minimum air temperature, soil thickness and available water capacity, soil texture, and land use. Long-term average annual precipitation, actual daily stream discharge, monthly estimates of base flow, Soil Conservation Service surface runoff curve numbers, land surface altitude-slope-aspect, and temperature lapse rates are optional. The program is written in the FORTRAN 77 language with no enhancements and should run on most computer systems without modifications. Documentation has been prepared so that program modifications may be made for inclusions of additional physical processes or deletion of ones not considered important. (Author 's abstract)

Use of existing patient-reported outcome (PRO) instruments and their modification: the ISPOR Good Research Practices for Evaluating and Documenting Content Validity for the Use of Existing Instruments and Their Modification PRO Task Force Report.

PubMed

Rothman, Margaret; Burke, Laurie; Erickson, Pennifer; Leidy, Nancy Kline; Patrick, Donald L; Petrie, Charles D

2009-01-01

Patient-reported outcome (PRO) instruments are used to evaluate the effect of medical products on how patients feel or function. This article presents the results of an ISPOR task force convened to address good clinical research practices for the use of existing or modified PRO instruments to support medical product labeling claims. The focus of the article is on content validity, with specific reference to existing or modified PRO instruments, because of the importance of content validity in selecting or modifying an existing PRO instrument and the lack of consensus in the research community regarding best practices for establishing and documenting this measurement property. Topics addressed in the article include: definition and general description of content validity; PRO concept identification as the important first step in establishing content validity; instrument identification and the initial review process; key issues in qualitative methodology; and potential threats to content validity, with three case examples used to illustrate types of threats and how they might be resolved. A table of steps used to identify and evaluate an existing PRO instrument is provided, and figures are used to illustrate the meaning of content validity in relationship to instrument development and evaluation. RESULTS & RECOMMENDATIONS: Four important threats to content validity are identified: unclear conceptual match between the PRO instrument and the intended claim, lack of direct patient input into PRO item content from the target population in which the claim is desired, no evidence that the most relevant and important item content is contained in the instrument, and lack of documentation to support modifications to the PRO instrument. In some cases, careful review of the threats to content validity in a specific application may be reduced through additional well documented qualitative studies that specifically address the issue of concern. Published evidence of the content validity of a PRO instrument for an intended application is often limited. Such evidence is, however, important to evaluating the adequacy of a PRO instrument for the intended application. This article provides an overview of key issues involved in assessing and documenting content validity as it relates to using existing instruments in the drug approval process.

Modifications to the 4x7 meter tunnel for acoustic research: Engineering feasibility study

NASA Technical Reports Server (NTRS)

1986-01-01

The NASA-Langley Research Center 4 x 7 Meter Low Speed Wind Tunnel is currently being used for low speed aerodynamics, V/STOL aerodynamics and, to a limited extent, rotorcraft noise research. The deficiencies of this wind tunnel for both aerodynamics and aeroacoustics research have been recognized for some time. Modifications to the wind tunnel are being made to improve the test section flow quality and to update the model cart systems. A further modification of the 4 x 7 Meter Wind Tunnel to permit rotorcraft model acoustics research has been proposed. As a precursor to the design of the proposed modifications, NASA is conducted both in-house and contracted studies to define the acoustic environment within the wind tunnel and to provide recommendations or the reduction of the wind tunnel background noise to a level acceptable to acoustics researchers. One of these studies by an acoustics consultant, has produced the primary reference documents that define the wind tunnel noise sources and outline recommended solutions.

76 FR 33245 - Endangered Species; File No. 15135

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

... sea turtles for purposes scientific research. ADDRESSES: The permit and related documents are..., notice was published in the Federal Register (75 FR 11863) that a request for a scientific research..., North Carolina. The objective of the research is to determine if gear modifications can eliminate or...

32 CFR 989.20 - Final EIS.

Code of Federal Regulations, 2010 CFR

2010-07-01

... limited to factual corrections and responses to comments, the proponent and EPF may, with the prior..., the EPF must submit the Draft EIS and all of the above documents, with a new cover sheet indicating... more extensive modifications are required, the EPF must prepare a preliminary final EIS incorporating...

Censorship--or Curriculum Modification? Revised.

ERIC Educational Resources Information Center

O'Reilly, Robert C.; Parker, Larry

The rights and responsibilities of boards of education in restricting the availability of certain materials through school libraries are considered in this report. The document first treats the relationship between the demands of the First Amendment and parents' expectations regarding the appropriateness of certain materials for their children.…

COMPUTER PROGRAM DOCUMENTATION FOR THE ENHANCED STREAM WATER QUALITY MODEL QUAL2E

EPA Science Inventory

Presented in the manual are recent modifications and improvements to the widely used stream water quality model QUAL-II. Called QUAL2E, the enhanced model incorporates improvements in eight areas: (1) algal, nitrogen, phosphorus, and dissolved oxygen interactions; (2) algal growt...

Constitution, 16 May 1984.

PubMed

1987-01-01

This document reprints portions of Guinea-Bissau's 1984 Constitution. The Constitution notes that public health efforts would be directed towards prevention as well as the progressive socialization of the health sector. Education is to be strictly linked to productive work and will strengthen an individual's position in the community. The elimination of illiteracy is considered a fundamental task of the state. All citizens are equal before the law, and men and women have equal legal status in all aspects of political, economic, social, and cultural life. The family is protected by the state, and children are equal before the law regardless of their parentage. Foreigners and stateless persons residing in Guinea-Bissau have the same rights and duties as citizens as permitted by law. Citizens have the right to health, and children, youth, and mothers have the right to social protection. All citizens have the right to equal access to educational opportunities.

WIPP Remote-Handled TRU Waste Program Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Most, W.; Kehrman, B.

2006-07-01

There are two major regulatory approval milestones necessary in order to commence disposal operations for remote-handled transuranic (RH TRU) waste at the Waste Isolation Pilot Plant (WIPP)-the RH TRU hazardous waste permit modification request [1] and the radiological characterization plan [2]. One of those milestones has been achieved. The US Environmental Protection Agency (EPA) issued its final decision to approve the Department of Energy's (DOE) RH TRU radiological characterization plan along with the RH TRU Waste Characterization Program Implementation Plan [3], on March 26, 2004. The RH TRU hazardous waste permit modification request still awaits agency approval. In EPA's decisionmore » to approve the DOE's RH TRU radiological characterization plan, the EPA also set forth the process for approving site-specific RH TRU waste characterization programs. Included in the March 29, 2005, RH TRU second Notice of Deficiency [4] (NOD) on the Class 3 Permit Modification Request for RH TRU Waste, the New Mexico Environment Department (NMED) requested that the Permittees combine their responses for the RH TRU Waste NOD with the Section 311 permit modification request NOD. The Combined Response Document was submitted April 28, 2005 [5]. Another NOD [6] was issued by the NMED on September 1, 2005, to clarify the Permittees' proposal and submit these clarifications to the administrative record. Combining both the chap. 311 [7] and RH TRU waste permit modification requests allows for both the regulator and Permittees to expedite action on the modification requests. The Combined Response Document preserves human resources and costs by having only one administrative process for both modification requests. Facility readiness requirements of the RH TRU waste final permit [8] must be implemented to declare that the WIPP is ready to receive RH TRU waste for storage and disposal. To demonstrate readiness, the WIPP is preparing for an Operational Readiness Review (ORR) of the RH TRU waste management equipment, system, and procedures. Required by DOE Order, the ORR demonstrates the capability of managing RH TRU waste. The Management and Operating Contractor (MOC) for the WIPP must first perform a Line Management Assessment. Upon successful completion of the Line Management Assessment, the MOC performs the Contractor ORR and presents the results to the local DOE office. At that time, the local DOE office performs its own ORR to declare readiness to DOE Headquarters. (authors)« less

[Bibliografic resources on chemical risk administration and prevention].

PubMed

Calera Rubio, Alfonso A; Juan Quilis, Verónica; López Samaniego, Luz M; Caballero Pérez, Pablo; Ronda Pérez, Elena

2005-01-01

The documentation produced by public and private institutions in relation to the chemical risk constitutes an essential tool for prevention. The objective of this research is to locate and to revise the documents related to the management of the prevention of chemical risk focus to PYMES in Spain from 1995 to 2004. The methodology carried out for the selection of the bibliographical materials has been the consultation of automated databases and Web pages. 812 documents have been identified. Most corresponds to grey literature. The thematic more frequent has been the security and the most frequent objective of the papers has been the prevention. Most of the documents go to the technical sector. The results suggest that although that there is a great diversity of documents in Spain dedicated to the prevention of chemical risk it seems convenient: 1) to increase their diffusion, 2) to pay attention to the communication of the risks, 3) to investigate and to translate the research in good practice.

Reference Model for an Open Archival Information System

NASA Technical Reports Server (NTRS)

1997-01-01

This document is a technical report for use in developing a consensus on what is required to operate a permanent, or indefinite long-term, archive of digital information. It may be useful as a starting point for a similar document addressing the indefinite long-term preservation of non-digital information. This report establishes a common framework of terms and concepts which comprise an Open Archival Information System (OAIS). It allows existing and future archives to be more meaningfully compared and contrasted. It provides a basis for further standardization of within an archival context and it should promote greater vendor awareness of, and support of , archival requirements. Through the process of normal evolution, it is expected that expansion, deletion, or modification to this document may occur. This report is therefore subject to CCSDS document management and change control procedures.

Software validation applied to spreadsheets used in laboratories working under ISO/IEC 17025

NASA Astrophysics Data System (ADS)

Banegas, J. M.; Orué, M. W.

2016-07-01

Several documents deal with software validation. Nevertheless, more are too complex to be applied to validate spreadsheets - surely the most used software in laboratories working under ISO/IEC 17025. The method proposed in this work is intended to be directly applied to validate spreadsheets. It includes a systematic way to document requirements, operational aspects regarding to validation, and a simple method to keep records of validation results and modifications history. This method is actually being used in an accredited calibration laboratory, showing to be practical and efficient.

Spinal cord testing: auditing for quality assurance.

PubMed

Marr, J A; Reid, B

1991-04-01

A quality assurance audit of spinal cord testing as documented by staff nurses was carried out. Twenty-five patient records were examined for accuracy of documented testing and compared to assessments performed by three investigators. A pilot study established interrater reliability of a tool that was designed especially for this study. Results indicated staff nurses failed to meet pre-established 100% standard in all categories of testing when compared with investigator's findings. Possible reasons for this disparity are discussed as well as indications for modifications in the spinal testing record, teaching program and preset standards.

Aircraft/Air Traffic Management Functional Analysis Model. Version 2.0; User's Guide

NASA Technical Reports Server (NTRS)

Etheridge, Melvin; Plugge, Joana; Retina, Nusrat

1998-01-01

The Aircraft/Air Traffic Management Functional Analysis Model, Version 2.0 (FAM 2.0), is a discrete event simulation model designed to support analysis of alternative concepts in air traffic management and control. FAM 2.0 was developed by the Logistics Management Institute (LMI) a National Aeronautics and Space Administration (NASA) contract. This document provides a guide for using the model in analysis. Those interested in making enhancements or modification to the model should consult the companion document, Aircraft/Air Traffic Management Functional Analysis Model, Version 2.0 Technical Description.

Detailed costing document for the centralized waste treatment industry

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-01

In this document, EPA presents the costs estimated for compliance with the proposed CWT effluent limitations guidelines and standards. Section 1 provides a general description of how the individual treatment technology and regulatory option costs were developed. In Sections 2 through 4, EPA describes the development of costs for each of the wastewater and sludge treatment technologies. In Section 5, EPA presents additional compliance costs to be incurred by facilities, which are not technology specific. These additional items are retrofit costs, monitoring costs, RCRA permit modification costs, and land costs.

The Work of Inscription: Antenatal Care, Birth Documents, and Shan Migrant Women in Chiang Mai.

PubMed

Seo, Bo Kyeong

2017-12-01

For transnational migrant populations, securing birth documents of newly born children has crucial importance in avoiding statelessness for new generations. Drawing on discussions of sovereignty and political subjectivization, I ask how the fact of birth is constituted in the context of transnational migration. Based on ethnographic data collected from an antenatal clinic in Thailand, this article describes how Shan migrant women from Myanmar (also known as Burma) utilize reproductive health services as a way of assuring a safe birth while acquiring identification documents. Paying close attention to technologies of inscription adopted for maternal care and birth registration, I argue that enacting bureaucratic documents offers a chance for migrant women to bridge the interstice between human and citizen. Birth certificates for migrant children, while embodying legal ambiguity and uncertainty, epitomize non-citizen subjects' assertion of their political relationship with the state. © 2016 by the American Anthropological Association.

Team X Report #1401: Exoplanet Coronagraph STDT Study 2013-06

NASA Technical Reports Server (NTRS)

Warfield, Keith

2013-01-01

This document is intended to stimulate discussion of the topic described. All technical and cost analyses are preliminary. This document is not a commitment to work, but is a precursor to a formal proposal if it generates sufficient mutual interest. The data contained in this document may not be modified in any way. Cost estimates described or summarized in this document were generated as part of a preliminary, first-order cost class identification as part of an early trade space study, are based on JPL-internal parametric cost modeling, assume a JPL in-house build, and do not constitute a commitment on the part of JPL or Caltech. JPL and Team X add cost reserves for development and operations. Unadjusted estimate totals and cost reserve allocations would be revised as needed in future more-detailed studies as appropriate for the specific cost-risks for a given mission concept.

Learning Style Activities for Computer Applications. Field Review.

ERIC Educational Resources Information Center

Patton, Jan

This document contains a composite of learning activities for use in a secondary-level course in business computer applications. The collection is unique in that the individual learning activities constituting it have each been tailored to one or more of the diverse learning styles possessed by individual students. The activities are grouped into…

Lincoln's Spot Resolutions. Teaching with Documents.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

Tension has existed between the legislative and the executive branches of the U.S. government over war powers since the United States Constitution simultaneously vested Congress with the power to declare war and the President with the power of Commander in Chief. When Texas declared its independence and claimed additional territory to the Rio…

40 CFR 725.29 - EPA acknowledgement of receipt of submission.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 30 2010-07-01 2010-07-01 false EPA acknowledgement of receipt of... Procedures § 725.29 EPA acknowledgement of receipt of submission. (a) EPA will acknowledge receipt of each... Toxics Document Control Officer. (b) The acknowledgement does not constitute a finding by EPA that the...

Religion & Public Schools: Striking a Constitutional Balance. Revised Edition.

ERIC Educational Resources Information Center

Gittins, Naomi E., Ed.

This document provides comprehensive analysis of new key developments in the law regarding the proper relationship between religion and public schools. There are 12 chapters: (1) "The First Amendment and Public Schools: Overview of the Religion Clauses" (John Walsh, Dorine Lawrence-Hughes, and Usi N. Botros); (2) "Prayer on Campus:…

The Challenge of Violence. [Student Text and] Teacher's Guide.

ERIC Educational Resources Information Center

Croddy, Marshall; Degelman, Charles; Hayes, Bill

This document addresses violence as one of the key challenges facing the democratic and pluralistic republic under the framework of the Constitution and its Bill of Rights. Primary focus is on criminal violence and the factors and behaviors that contribute to violent crime. The text is organized into three chapters: (1) "The Problem of…

The Italian-American Novel: A Document of the Interaction of Two Cultures.

ERIC Educational Resources Information Center

Green, Rose Basile

A chronological analysis of the fictional writings of Americans of Italian ancestry, this book constitutes a record of the interaction of two cultures, immigrant and established, within the composition of American civilization. The materials are divided into three parts: the first part contains an analysis of representative autobiographies as a…

Hide and Seek: Values in Early Childhood Education and Care

ERIC Educational Resources Information Center

Powell, Sacha

2010-01-01

Early childhood education and care settings in England and the people who work in them constitute an important sphere of influence, shaping young children's characters and values. But the values and dispositions expected of the early years workforce are missing from statutory policy documentation despite its clear requirement that practitioners…

Tolerance for Diversity of Beliefs: A Secondary Curriculum Unit.

ERIC Educational Resources Information Center

Avery, Patricia; And Others

This document consists on a 6-week curriculum unit designed to allow secondary students to actively explore issues associated with freedom of belief and expression. Throughout the curriculum students systematically examine the ways in which the legal and constitutional framework of our society directly embodies the norms of freedom of speech and…

Genetic improvement of disease resistance in salmonid fish using selective breeding: Overview of concepts, considerations and limitations

USDA-ARS?s Scientific Manuscript database

In aquaculture, endemic infectious diseases constitute a considerable economic burden due to direct losses as well as indirect impacts on growth and animal welfare. In response to infectious disease, it is well documented that host genetic variation is present in most animal populations, especially ...

Electoral Law: Documents on Politics and Society in the Federal Republic of Germany.

ERIC Educational Resources Information Center

Inter Nationes, Bonn (West Germany).

Free elections are one of the fundamental principles of any parliamentary democracy. The constitution of the Federal Republic of Germany, the Basic Law, stipulates in its article 20(2) that "all state authority emanates from the people" who exercise that authority "by means of elections and referendums and through special…

Gender, Reputation and Regret: The Ontological Politics of Australian Drug Education

ERIC Educational Resources Information Center

Farrugia, Adrian

2017-01-01

This study explores the role of gender in the constitution youth alcohol and other drug consumption in Australian drug education curriculum. Drawn from an analysis of contemporary classroom drug education documents, it is argued that current drug education reproduces unethical and harmful accounts of femininity and masculinity. These enactments of…

18 CFR 284.123 - Rates and charges.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Rates and charges. 284... filing constitutes a certification that the contents are true to the best knowledge and belief of the... document included in the filing must comply, where applicable, with the requirements in § 385.2005 of this...

18 CFR 284.123 - Rates and charges.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Rates and charges. 284... filing constitutes a certification that the contents are true to the best knowledge and belief of the... document included in the filing must comply, where applicable, with the requirements in § 385.2005 of this...

18 CFR 284.123 - Rates and charges.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Rates and charges. 284... filing constitutes a certification that the contents are true to the best knowledge and belief of the... document included in the filing must comply, where applicable, with the requirements in § 385.2005 of this...

18 CFR 284.123 - Rates and charges.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Rates and charges. 284... filing constitutes a certification that the contents are true to the best knowledge and belief of the... document included in the filing must comply, where applicable, with the requirements in § 385.2005 of this...

18 CFR 284.123 - Rates and charges.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Rates and charges. 284... filing constitutes a certification that the contents are true to the best knowledge and belief of the... document included in the filing must comply, where applicable, with the requirements in § 385.2005 of this...

Gender-Sensitive Education for a Better World. Background Document.

ERIC Educational Resources Information Center

Aksornkool, Namtip

Economic restructuring has severely affected the education of girls, particularly in the poorest and least developed countries where poverty is the major obstacle to education. Girls still constitute the majority of children not enrolled in school, and illiteracy among women remains one of the biggest challenges for the 21st century. Deep-rooted…

29 CFR 1601.13 - Filing; deferrals to State and local agencies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... State and local agencies. The Commission shall endeavor to maintain close communication with the State... deemed to be filed with the Commission as follows: (A) Where the document on its face constitutes a... 29 Labor 4 2010-07-01 2010-07-01 false Filing; deferrals to State and local agencies. 1601.13...

U. S. National Report on the Human Environment.

ERIC Educational Resources Information Center

Department of State, Washington, DC.

This document constitutes the response of the United States to the request that members of the United Nations participating in the Conference on the Human Environment in Stockholm prepare national reports describing their environmental problems and discuss actions being taken to resolve them. In addition, members were asked to identify topics of…

Contemporary Perspectives in Adult Education and Lifelong Learning -- Andragogical Model of Learning

ERIC Educational Resources Information Center

Blaszczak, Iwona

2013-01-01

Nowadays, adult education and lifelong learning constitutes one of the most significant factors influencing economic growth and social development. Definitions such as "knowledge society" and "knowledge-based economy" exist in a great number of the Polish and European Union papers and documents and they are not only the…

12 CFR 621.7 - Rule of aggregation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... constitutes an independent credit risk and such determination is adequately documented in the loan file. (1) A loan shall be considered an independent credit risk if a substantial portion of the loan is guaranteed... credit risks if and so long as: (i) The primary sources of repayment are independent for each loan; (ii...

Fall 1972 University Racial Census.

ERIC Educational Resources Information Center

Brooks, Glenwood C., Jr.; Sedlacek, William E.

This document reports the results of the fall 1972 racial census at the University of Maryland. Only new freshmen, transfer students, and readmitted students filled out the racial census cards. All returning students constituted the data base of the student body. By adding new and deleting old racial census cards, counts could be made. Results of…

Dullgren extraction of soil mites (Acarina): Effect of refrigeration time on extraction efficiency

Treesearch

Michelle B. Lakly; D.A. Crossley

2000-01-01

Soil microarthropods constitute one of the most species rich communities in . forest ecosystems (Crossley & Blair, 1991). The effects of soil fauna in these systems on decomposition rates, nutrient regeneration and soil structure have been well documented; however, dependable estimates of population size and community structure largely depend upon adequate sampling...

Education in Alaska's Past. Proceedings of the Annual Meeting of the Alaska Historical Society (Valdez, Alaska, October 8-9, 1982).

ERIC Educational Resources Information Center

Stein, Gary, Ed.

The 14 symposium papers presented in this document provide a diverse historical and personal interpretation of Alaska's educational development. Titles and authors are: "Conflicting Priorities, Conflicting Opinions: Alaskan Development and Sheldon Jackson, Educator" (Ted Hinckley); "Sheldon Jackson and the Constitutionality of the…

Depression in Adolescence: Current Knowledge, Research Directions, and Implications for Programs and Policy.

ERIC Educational Resources Information Center

Petersen, Anne C.; And Others

This document focuses on adolescent depression, described as a major, pervasive, and perhaps increasing problem. A brief introduction to depression in adolescence, with case examples, is followed by a discussion of what constitutes adolescent depression. Depressed mood, depressive syndromes, and clinical depression are three approaches taken in…

Challenging Student Behaviour

ERIC Educational Resources Information Center

Jones, Glyn; Philp, Clare

2011-01-01

The issue of poor student behaviour within higher education institutions (HEIs) has been well documented in recent years. Although the number of reported cases constitutes a very small percentage of the overall student population in the UK, the impact of student misconduct on the rest of the student body and staff in HEIs can be substantial. For…

How Fares Law-Related Education?

ERIC Educational Resources Information Center

Anderson, Charlotte C.

1987-01-01

This document examines the state of the law-related education (LRE) movement, which began about 25 years ago with the efforts of teachers and lawyers who wanted to give greater attention to the Constitution and the Bill of Rights. Descriptions are given of 10 successful high school LRE programs and 5 supportive national organizations. A 3-year…

Modeling Damage and Fragmentation in Concrete

DTIC Science & Technology

2007-04-01

Department of the Army position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute...then deduced as ψρ ∂= ∂ E Eσ F E ETF , ψη ρ θ ∂ = − ∂ . (10) The dissipation inequality (8) is then given by 1ˆ: 1 p D

76 FR 22289 - Prohibiting Certain Transactions With Respect to North Korea

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

... Certain Transactions With Respect to North Korea #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal... With Respect to North Korea By the authority vested in me as President by the Constitution and the laws... term ``North Korea'' includes the territory of the Democratic People's Republic of Korea and the...

Commentary on A General Curriculum in Mathematics for Colleges.

ERIC Educational Resources Information Center

Committee on the Undergraduate Program in Mathematics, Berkeley, CA.

This document constitutes a complete revision of the report of the same name first published in 1965. A new list of basic courses is described, consisting of Calculus I, Calculus II, Elementary Linear Algebra, Multivariable Calculus I, Linear Algebra, and Introductory Modern Algebra. Commentaries outline the content and spirit of these courses in…

19 CFR 24.3 - Bills and accounts; receipts.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Bills and accounts; receipts. 24.3 Section 24.3... TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.3 Bills and accounts; receipts. (a) Any bill or... document filed by the payer and the payer's cancelled check shall constitute evidence of payment. (c) A...

19 CFR 24.3 - Bills and accounts; receipts.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Bills and accounts; receipts. 24.3 Section 24.3... TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.3 Bills and accounts; receipts. (a) Any bill or... document filed by the payer and the payer's cancelled check shall constitute evidence of payment. (c) A...

19 CFR 24.3 - Bills and accounts; receipts.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Bills and accounts; receipts. 24.3 Section 24.3... TREASURY CUSTOMS FINANCIAL AND ACCOUNTING PROCEDURE § 24.3 Bills and accounts; receipts. (a) Any bill or... document filed by the payer and the payer's cancelled check shall constitute evidence of payment. (c) A...