Enhancing spatial resolution of 18F positron imaging with the Timepix detector by classification of primary fired pixels using support vector machine

NASA Astrophysics Data System (ADS)

Wang, Qian; Liu, Zhen; Ziegler, Sibylle I.; Shi, Kuangyu

2015-07-01

Position-sensitive positron cameras using silicon pixel detectors have been applied for some preclinical and intraoperative clinical applications. However, the spatial resolution of a positron camera is limited by positron multiple scattering in the detector. An incident positron may fire a number of successive pixels on the imaging plane. It is still impossible to capture the primary fired pixel along a particle trajectory by hardware or to perceive the pixel firing sequence by direct observation. Here, we propose a novel data-driven method to improve the spatial resolution by classifying the primary pixels within the detector using support vector machine. A classification model is constructed by learning the features of positron trajectories based on Monte-Carlo simulations using Geant4. Topological and energy features of pixels fired by 18F positrons were considered for the training and classification. After applying the classification model on measurements, the primary fired pixels of the positron tracks in the silicon detector were estimated. The method was tested and assessed for [18F]FDG imaging of an absorbing edge protocol and a leaf sample. The proposed method improved the spatial resolution from 154.6   ±   4.2 µm (energy weighted centroid approximation) to 132.3   ±   3.5 µm in the absorbing edge measurements. For the positron imaging of a leaf sample, the proposed method achieved lower root mean square error relative to phosphor plate imaging, and higher similarity with the reference optical image. The improvements of the preliminary results support further investigation of the proposed algorithm for the enhancement of positron imaging in clinical and preclinical applications.

The electronics system for the LBNL positron emission mammography (PEM) camera

NASA Astrophysics Data System (ADS)

Moses, W. W.; Young, J. W.; Baker, K.; Jones, W.; Lenox, M.; Ho, M. H.; Weng, M.

2001-06-01

Describes the electronics for a high-performance positron emission mammography (PEM) camera. It is based on the electronics for a human brain positron emission tomography (PET) camera (the Siemens/CTI HRRT), modified to use a detector module that incorporates a photodiode (PD) array. An application-specified integrated circuit (ASIC) services the photodetector (PD) array, amplifying its signal and identifying the crystal of interaction. Another ASIC services the photomultiplier tube (PMT), measuring its output and providing a timing signal. Field-programmable gate arrays (FPGAs) and lookup RAMs are used to apply crystal-by-crystal correction factors and measure the energy deposit and the interaction depth (based on the PD/PMT ratio). Additional FPGAs provide event multiplexing, derandomization, coincidence detection, and real-time rebinning. Embedded PC/104 microprocessors provide communication, real-time control, and configure the system. Extensive use of FPGAs make the overall design extremely flexible, allowing many different functions (or design modifications) to be realized without hardware changes. Incorporation of extensive onboard diagnostics, implemented in the FPGAs, is required by the very high level of integration and density achieved by this system.

Design and Development of a Low-Cost Aerial Mobile Mapping System for Multi-Purpose Applications

NASA Astrophysics Data System (ADS)

Acevedo Pardo, C.; Farjas Abadía, M.; Sternberg, H.

2015-08-01

The research project with the working title "Design and development of a low-cost modular Aerial Mobile Mapping System" was formed during the last year as the result from numerous discussions and considerations with colleagues from the HafenCity University Hamburg, Department Geomatics. The aim of the project is to design a sensor platform which can be embedded preferentially on an UAV, but also can be integrated on any adaptable vehicle. The system should perform a direct scanning of surfaces with a laser scanner and supported through sensors for determining the position and attitude of the platform. The modular design allows his extension with other sensors such as multispectral cameras, digital cameras or multiple cameras systems.

Positron Annihilation in Thunderstorms Observed by ILDAS.

NASA Astrophysics Data System (ADS)

Kochkin, P.; Sarria, D., Sr.; Van Deursen, A.; de Boer, A.; Bardet, M.; Allasia, C.; Flourens, F.; Østgaard, N.

2017-12-01

Positron clouds within thunderstorms were for the first time reported in 2015 [Dwyer et al. 2015]. The observation was made by the Airborne Detector for Energetic Lightning Emissions (ADELE) in 2009 at 14.1 km altitude. Strong 511 keV line enhancement was recorded synchronously with nearby electrical activity. It lasted at least 0.2 s and was modeled as annihilation from disperse positron cloud more than a kilometer across. Different positron generation mechanisms were proposed in the paper. In January 2016 an Airbus A340 factory test aircraft was intentionally flying through thunderstorms over Northern Australia. The aircraft was equipped with a dedicated in-flight lightning detection system ILDAS (http://ildas.nlr.nl). The system contains two gamma-ray scintillation detectors each with 38x38 mm cylinder LaBr3 crystals. Total 9 video cameras were installed on-board to monitor the outer surfaces. When the aircraft flew at 12 km inside an active thundercloud, the ambient electric field was strong enough to trigger electrical discharges from the sharp edges. One sequence of such discharges was accompanied with enhancements of 511 keV line, each lasted for 0.5 - 1.0 s and total duration over 15 s. The video cameras recorded electrical discharges attached to the aircraft during this process. ILDAS reported brief 100 A current pulses in association with these discharges. Ground-based lightning location networks, i.e. WWLLN and local Australian LIAS, have not detected any sferics from this region. A detailed Geant4 model of the aircraft was created. The model was used to test different production mechanisms for the observed emission. In this presentation we will show a detailed reconstruction ofthe events with precise mapping on infrared cloud snapshot. Videos from the cameras at the positron detection moment will be shown. The results of the Geant4 simulation will be presented and discussed. References: 1. Dwyer, Joseph R., et al. "Positron clouds within thunderstorms." Journal of Plasma Physics 81.4 (2015).

High resolution Cerenkov light imaging of induced positron distribution in proton therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamamoto, Seiichi, E-mail: s-yama@met.nagoya-u.ac.jp; Fujii, Kento; Morishita, Yuki

2014-11-01

Purpose: In proton therapy, imaging of the positron distribution produced by fragmentation during or soon after proton irradiation is a useful method to monitor the proton range. Although positron emission tomography (PET) is typically used for this imaging, its spatial resolution is limited. Cerenkov light imaging is a new molecular imaging technology that detects the visible photons that are produced from high-speed electrons using a high sensitivity optical camera. Because its inherent spatial resolution is much higher than PET, the authors can measure more precise information of the proton-induced positron distribution with Cerenkov light imaging technology. For this purpose, theymore » conducted Cerenkov light imaging of induced positron distribution in proton therapy. Methods: First, the authors evaluated the spatial resolution of our Cerenkov light imaging system with a {sup 22}Na point source for the actual imaging setup. Then the transparent acrylic phantoms (100 × 100 × 100 mm{sup 3}) were irradiated with two different proton energies using a spot scanning proton therapy system. Cerenkov light imaging of each phantom was conducted using a high sensitivity electron multiplied charge coupled device (EM-CCD) camera. Results: The Cerenkov light’s spatial resolution for the setup was 0.76 ± 0.6 mm FWHM. They obtained high resolution Cerenkov light images of the positron distributions in the phantoms for two different proton energies and made fused images of the reference images and the Cerenkov light images. The depths of the positron distribution in the phantoms from the Cerenkov light images were almost identical to the simulation results. The decay curves derived from the region-of-interests (ROIs) set on the Cerenkov light images revealed that Cerenkov light images can be used for estimating the half-life of the radionuclide components of positrons. Conclusions: High resolution Cerenkov light imaging of proton-induced positron distribution was possible. The authors conclude that Cerenkov light imaging of proton-induced positron is promising for proton therapy.« less

Prototype color field sequential television lens assembly

NASA Technical Reports Server (NTRS)

1974-01-01

The design, development, and evaluation of a prototype modular lens assembly with a self-contained field sequential color wheel is presented. The design of a color wheel of maximum efficiency, the selection of spectral filters, and the design of a quiet, efficient wheel drive system are included. Design tradeoffs considered for each aspect of the modular assembly are discussed. Emphasis is placed on achieving a design which can be attached directly to an unmodified camera, thus permitting use of the assembly in evaluating various candidate camera and sensor designs. A technique is described which permits maintaining high optical efficiency with an unmodified camera. A motor synchronization system is developed which requires only the vertical synchronization signal as a reference frequency input. Equations and tradeoff curves are developed to permit optimizing the filter wheel aperture shapes for a variety of different design conditions.

Evaluation of Origin Ensemble algorithm for image reconstruction for pixelated solid-state detectors with large number of channels

NASA Astrophysics Data System (ADS)

Kolstein, M.; De Lorenzo, G.; Mikhaylova, E.; Chmeissani, M.; Ariño, G.; Calderón, Y.; Ozsahin, I.; Uzun, D.

2013-04-01

The Voxel Imaging PET (VIP) Pathfinder project intends to show the advantages of using pixelated solid-state technology for nuclear medicine applications. It proposes designs for Positron Emission Tomography (PET), Positron Emission Mammography (PEM) and Compton gamma camera detectors with a large number of signal channels (of the order of 106). For PET scanners, conventional algorithms like Filtered Back-Projection (FBP) and Ordered Subset Expectation Maximization (OSEM) are straightforward to use and give good results. However, FBP presents difficulties for detectors with limited angular coverage like PEM and Compton gamma cameras, whereas OSEM has an impractically large time and memory consumption for a Compton gamma camera with a large number of channels. In this article, the Origin Ensemble (OE) algorithm is evaluated as an alternative algorithm for image reconstruction. Monte Carlo simulations of the PET design are used to compare the performance of OE, FBP and OSEM in terms of the bias, variance and average mean squared error (MSE) image quality metrics. For the PEM and Compton camera designs, results obtained with OE are presented.

A modular approach to detection and identification of defects in rough lumber

Treesearch

Sang Mook Lee; A. Lynn Abbott; Daniel L. Schmoldt

2001-01-01

This paper describes a prototype scanning system that can automatically identify several important defects on rough hardwood lumber. The scanning system utilizes 3 laser sources and an embedded-processor camera to capture and analyze profile and gray-scale images. The modular approach combines the detection of wane (the curved sides of a board, possibly containing...

Characterization of the LBNL PEM Camera

NASA Astrophysics Data System (ADS)

Wang, G.-C.; Huber, J. S.; Moses, W. W.; Qi, J.; Choong, W.-S.

2006-06-01

We present the tomographic images and performance measurements of the LBNL positron emission mammography (PEM) camera, a specially designed positron emission tomography (PET) camera that utilizes PET detector modules with depth of interaction measurement capability to achieve both high sensitivity and high resolution for breast cancer detection. The camera currently consists of 24 detector modules positioned as four detector banks to cover a rectangular patient port that is 8.2/spl times/6 cm/sup 2/ with a 5 cm axial extent. Each LBNL PEM detector module consists of 64 3/spl times/3/spl times/30 mm/sup 3/ LSO crystals coupled to a single photomultiplier tube (PMT) and an 8/spl times/8 silicon photodiode array (PD). The PMT provides accurate timing, the PD identifies the crystal of interaction, the sum of the PD and PMT signals (PD+PMT) provides the total energy, and the PD/(PD+PMT) ratio determines the depth of interaction. The performance of the camera has been evaluated by imaging various phantoms. The full-width-at-half-maximum (FWHM) spatial resolution changes slightly from 1.9 mm to 2.1 mm when measured at the center and corner of the field of the view, respectively, using a 6 ns coincidence timing window and a 300-750 keV energy window. With the same setup, the peak sensitivity of the camera is 1.83 kcps//spl mu/Ci.

Radionuclides in Diagnosis.

ERIC Educational Resources Information Center

Williams, E. D.

1989-01-01

Discussed is a radionuclide imaging technique, including the gamma camera, image analysis computer, radiopharmaceuticals, and positron emission tomography. Several pictures showing the use of this technique are presented. (YP)

The Modular Optical Underwater Survey System

PubMed Central

Amin, Ruhul; Richards, Benjamin L.; Misa, William F. X. E.; Taylor, Jeremy C.; Miller, Dianna R.; Rollo, Audrey K.; Demarke, Christopher; Ossolinski, Justin E.; Reardon, Russell T.; Koyanagi, Kyle H.

2017-01-01

The Pacific Islands Fisheries Science Center deploys the Modular Optical Underwater Survey System (MOUSS) to estimate the species-specific, size-structured abundance of commercially-important fish species in Hawaii and the Pacific Islands. The MOUSS is an autonomous stereo-video camera system designed for the in situ visual sampling of fish assemblages. This system is rated to 500 m and its low-light, stereo-video cameras enable identification, counting, and sizing of individuals at a range of 0.5–10 m. The modular nature of MOUSS allows for the efficient and cost-effective use of various imaging sensors, power systems, and deployment platforms. The MOUSS is in use for surveys in Hawaii, the Gulf of Mexico, and Southern California. In Hawaiian waters, the system can effectively identify individuals to a depth of 250 m using only ambient light. In this paper, we describe the MOUSS’s application in fisheries research, including the design, calibration, analysis techniques, and deployment mechanism. PMID:29019962

Clinical trials of the prototype Rutherford Appleton Laboratory MWPC positron camera at the Royal Marsden Hospital

NASA Astrophysics Data System (ADS)

Flower, M. A.; Ott, R. J.; Webb, S.; Leach, M. O.; Marsden, P. K.; Clack, R.; Khan, O.; Batty, V.; McCready, V. R.; Bateman, J. E.

1988-06-01

Two clinical trials of the prototype RAL multiwire proportional chamber (MWPC) positron camera were carried out prior to the development of a clinical system with large-area detectors. During the first clinical trial, the patient studies included skeletal imaging using 18F, imaging of brain glucose metabolism using 18F FDG, bone marrow imaging using 52Fe citrate and thyroid imaging with Na 124I. Longitudinal tomograms were produced from the limited-angle data acquisition from the static detectors. During the second clinical trial, transaxial, coronal and sagittal images were produced from the multiview data acquisition. A more detailed thyroid study was performed in which the volume of the functioning thyroid tissue was obtained from the 3D PET image and this volume was used in estimating the radiation dose achieved during radioiodine therapy of patients with thyrotoxicosis. Despite the small field of view of the prototype camera, and the use of smaller than usual amounts of activity administered, the PET images were in most cases comparable with, and in a few cases visually better than, the equivalent planar view using a state-of-the-art gamma camera with a large field of view and routine radiopharmaceuticals.

A Modular, Reconfigurable Surveillance UAV Architecture

DTIC Science & Technology

2003-09-02

Una Società Galileo Avionica A Modular, Reconfigurable Surveillance UAV Architecture METEOR, Finmeccanica Group Zona Industriale di Soleschiano Via...ES) METEOR, Finmeccanica Group Zona Industriale di Soleschiano Via Mario Stoppani 21 34077 Ronchi dei Legionari (GO) ITALY 8. PERFORMING...PMSFMS RS1Backup FMS NSU Payload Control Actuators Router Router RS2 Recovery Devices Una Società Galileo Avionica • Daylight TV Camera • IR Sensor • HR

Modification of a medical PET scanner for PEPT studies

NASA Astrophysics Data System (ADS)

Sadrmomtaz, Alireza; Parker, D. J.; Byars, L. G.

2007-04-01

Over the last 20 years, positron emission tomography (PET) has developed as the most powerful functional imaging modality in medicine. Over the same period the University of Birmingham Positron Imaging Centre has applied PET to study engineering processes and developed the alternative technique of positron emission particle tracking (PEPT) in which a single radioactively labelled tracer particle is tracked by detecting simultaneously the pairs of back-to-back photons arising from positron/electron annihilation. Originally PEPT was performed using a pair of multiwire detectors, and more recently using a pair of digital gamma camera heads. In 2002 the Positron Imaging Centre acquired a medical PET scanner, an ECAT 931/08, previously used at Hammersmith Hospital. This scanner has been rebuilt in a flexible geometry for use in PEPT studies. This paper presents initial results from this system. Fast moving tracer particles can be rapidly and accurately located.

Detector for positronium temperature measurements by two-photon angular correlation

NASA Astrophysics Data System (ADS)

Cecchini, G. G.; Jones, A. C. L.; Fuentes-Garcia, M.; Adams, D. J.; Austin, M.; Membreno, E.; Mills, A. P.

2018-05-01

We report on the design and characterization of a modular γ-ray detector assembly developed for accurate and efficient detection of coincident 511 keV back-to-back γ-rays following electron-positron annihilation. Each modular detector consists of 16 narrow lutetium yttrium oxyorthosilicate scintillators coupled to a multi-anode Hamamatsu H12700B photomultiplier tube. We discuss the operation and optimization of 511 keV γ-ray detection resulting from testing various scintillators and detector arrangements concluding with an estimate of the coincident 511 keV detection efficiency for the intended experiment and a preliminary test representing one-quarter of the completed array.

Characterization of a transmission positron/positronium converter for antihydrogen production

NASA Astrophysics Data System (ADS)

Aghion, S.; Amsler, C.; Ariga, T.; Bonomi, G.; Brusa, R. S.; Caccia, M.; Caravita, R.; Castelli, F.; Cerchiari, G.; Comparat, D.; Consolati, G.; Demetrio, A.; Di Noto, L.; Doser, M.; Ereditato, A.; Evans, C.; Ferragut, R.; Fesel, J.; Fontana, A.; Gerber, S.; Giammarchi, M.; Gligorova, A.; Guatieri, F.; Haider, S.; Hinterberger, A.; Holmestad, H.; Kellerbauer, A.; Krasnický, D.; Lagomarsino, V.; Lansonneur, P.; Lebrun, P.; Malbrunot, C.; Mariazzi, S.; Matveev, V.; Mazzotta, Z.; Müller, S. R.; Nebbia, G.; Nedelec, P.; Oberthaler, M.; Pacifico, N.; Pagano, D.; Penasa, L.; Petracek, V.; Povolo, L.; Prelz, F.; Prevedelli, M.; Ravelli, L.; Resch, L.; Rienäcker, B.; Robert, J.; Røhne, O. M.; Rotondi, A.; Sacerdoti, M.; Sandaker, H.; Santoro, R.; Scampoli, P.; Simon, M.; Smestad, L.; Sorrentino, F.; Testera, G.; Tietje, I. C.; Widmann, E.; Yzombard, P.; Zimmer, C.; Zmeskal, J.; Zurlo, N.; Andersen, S. L.; Chevallier, J.; Uggerhøj, U. I.; Lyckegaard, F.

2017-09-01

In this work a characterization study of forward emission from a thin, meso-structured silica positron/positronium (Ps) converter following implantation of positrons in light of possible antihydrogen production is presented. The target consisted of a ∼1 μm thick ultraporous silica film e-gun evaporated onto a 20 nm carbon foil. The Ps formation and emission was studied via Single Shot Positron Annihilation Lifetime Spectroscopy measurements after implantation of pulses with 3 - 4 ·107 positrons and 10 ns temporal width. The forward emission of implanted positrons and secondary electrons was investigated with a micro-channel plate - phosphor screen assembly, connected either to a CCD camera for imaging of the impinging particles, or to a fast photomultiplier tube to extract information about their time of flight. The maximum Ps formation fraction was estimated to be ∼10%. At least 10% of the positrons implanted with an energy of 3.3 keV are forward-emitted with a scattering angle smaller than 50° and maximum kinetic energy of 1.2 keV. At least 0.1-0.2 secondary electrons per implanted positron were also found to be forward-emitted with a kinetic energy of a few eV. The possible application of this kind of positron/positronium converter for antihydrogen production is discussed.

Routine 18F-2-deoxy-2-fluoro-D-glucose (18F-FDG) myocardial tomography using a normal large field of view gamma-camera.

PubMed

Höflin, F; Ledermann, H; Noelpp, U; Weinreich, R; Rösler, H

1989-12-01

There is a recent need to study glucose metabolism of the heart in ischemic, as well as in "hibernating or stunned" myocardium, and compare it with that in perfusion studies. In non-positron emission tomography centers, positron imaging is possible with a standard Anger-type camera if proper collimation and adequate shielding of the camera crystal can be achieved. For the study with fast-decaying isotopes, seven-pinhole tomography (7PHT), a limited-angle method designed for transaxial tomography of the left ventricle using a nonrotating camera, is well suited, because projections are acquired simultaneously. Individual adjustment (patient supine) of the camera's view axis (CAx) with the left ventricular axis (LVAx) gives excellent results: sensitivity for CHD 82%, specificity 72% in a prospective 201TI study (48 patients, x-ray coronarography as reference). Good alignment of CAx with LVAx is also achieved with the patient prone in LAO in a hammock above the camera surface. In this setting additional lead shielding of the camera is possible using a table reinforced with 5 cm of lead with a central hole for the 7PH-collimator, which has a special lead inlay. This allows utilization of the 511 KeV emitter 18F-FDG, which with a half-life of 109 minutes, can be transported a reasonable distance from the production site. System sensitivity and resolution for 18F was found comparable to 201Tl, 99mTc, and 123I using a phantom. First clinical examinations after 201Tl stress/redistribution studies showed increased 18F-FDG uptake in ischemic heart segments, as well as in "hibernating" nonperfused or "stunned" myocardium.

Review: comparison of PET rubidium-82 with conventional SPECT myocardial perfusion imaging

PubMed Central

Ghotbi, Adam A; Kjær, Andreas; Hasbak, Philip

2014-01-01

Nuclear cardiology has for many years been focused on gamma camera technology. With ever improving cameras and software applications, this modality has developed into an important assessment tool for ischaemic heart disease. However, the development of new perfusion tracers has been scarce. While cardiac positron emission tomography (PET) so far largely has been limited to centres with on-site cyclotron, recent developments with generator produced perfusion tracers such as rubidium-82, as well as an increasing number of PET scanners installed, may enable a larger patient flow that may supersede that of gamma camera myocardial perfusion imaging. PMID:24028171

Modular telerobot control system for accident response

NASA Astrophysics Data System (ADS)

Anderson, Richard J. M.; Shirey, David L.

1999-08-01

The Accident Response Mobile Manipulator System (ARMMS) is a teleoperated emergency response vehicle that deploys two hydraulic manipulators, five cameras, and an array of sensors to the scene of an incident. It is operated from a remote base station that can be situated up to four kilometers away from the site. Recently, a modular telerobot control architecture called SMART was applied to ARMMS to improve the precision, safety, and operability of the manipulators on board. Using SMART, a prototype manipulator control system was developed in a couple of days, and an integrated working system was demonstrated within a couple of months. New capabilities such as camera-frame teleoperation, autonomous tool changeout and dual manipulator control have been incorporated. The final system incorporates twenty-two separate modules and implements seven different behavior modes. This paper describes the integration of SMART into the ARMMS system.

Development of an LYSO based gamma camera for positron and scinti-mammography

NASA Astrophysics Data System (ADS)

Liang, H.-C.; Jan, M.-L.; Lin, W.-C.; Yu, S.-F.; Su, J.-L.; Shen, L.-H.

2009-08-01

In this research, characteristics of combination of PSPMTs (position sensitive photo-multiplier tube) to form a larger detection area is studied. A home-made linear divider circuit was built for merging signals and readout. Borosilicate glasses were chosen for the scintillation light sharing in the crossover region. Deterioration effect caused by the light guide was understood. The influences of light guide and crossover region on the separable crystal size were evaluated. According to the test results, a gamma camera with a crystal block of 90 × 90 mm2 covered area, composed of 2 mm LYSO crystal pixels, was designed and fabricated. Measured performances showed that this camera worked fine in both 511 keV and lower energy gammas. The light loss behaviour within the crossover region was analyzed and realized. Through count rate measurements, the 176Lu nature background didn't show severe influence on the single photon imaging and exhibited an amount of less than 1/3 of all the events acquired. These results show that with using light sharing techniques, combination of multiple PSPMTs in both X and Y directions to build a large area imaging detector is capable to be achieved. Also this camera design is feasible to keep both the abilities for positron and single photon breast imaging applications. Separable crystal size is 2 mm with 2 mm thick glass applied for the light sharing in current status.

NectarCAM, a camera for the medium sized telescopes of the Cherenkov telescope array

NASA Astrophysics Data System (ADS)

Glicenstein, J.-F.; Shayduk, M.

2017-01-01

NectarCAM is a camera proposed for the medium-sized telescopes of the Cherenkov Telescope Array (CTA) which covers the core energy range of 100 GeV to 30 TeV. It has a modular design and is based on the NECTAr chip, at the heart of which is a GHz sampling Switched Capacitor Array and 12-bit Analog to Digital converter. The camera will be equipped with 265 7-photomultiplier modules, covering a field of view of 8 degrees. Each module includes photomultiplier bases, high voltage supply, pre-amplifier, trigger, readout and Ethernet transceiver. The recorded events last between a few nanoseconds and tens of nanoseconds. The expected performance of the camera are discussed. Prototypes of NectarCAM components have been built to validate the design. Preliminary results of a 19-module mini-camera are presented, as well as future plans for building and testing a full size camera.

Positron emission particle tracking and its application to granular media

NASA Astrophysics Data System (ADS)

Parker, D. J.

2017-05-01

Positron emission particle tracking (PEPT) is a technique for tracking a single radioactively labelled particle. Accurate 3D tracking is possible even when the particle is moving at high speed inside a dense opaque system. In many cases, tracking a single particle within a granular system provides sufficient information to determine the time-averaged behaviour of the entire granular system. After a general introduction, this paper describes the detector systems (PET scanners and positron cameras) used to record PEPT data, the techniques used to label particles, and the algorithms used to process the data. This paper concentrates on the use of PEPT for studying granular systems: the focus is mainly on work at Birmingham, but reference is also made to work from other centres, and options for wider diversification are suggested.

A Lower-Cost High-Resolution LYSO Detector Development for Positron Emission Mammography (PEM)

PubMed Central

Ramirez, Rocio A.; Zhang, Yuxuan; Liu, Shitao; Li, Hongdi; Baghaei, Hossain; An, Shaohui; Wang, Chao; Jan, Meei-Ling; Wong, Wai-Hoi

2010-01-01

In photomultiplier-quadrant-sharing (PQS) geometry for positron emission tomography applications, each PMT is shared by four blocks and each detector block is optically coupled to four round PMTs. Although this design reduces the cost of high-resolution PET systems, when the camera consists of detector panels that are made up of square blocks, half of the PMT’s sensitive window remains unused at the detector panel edge. Our goal was to develop a LYSO detector panel which minimizes the unused portion of the PMTs for a low-cost, high-resolution, and high-sensitivity positron emission mammography (PEM) camera. We modified the PQS design by using elongated blocks at panel edges and square blocks in the inner area. For elongated blocks, symmetric and asymmetrical reflector patterns were developed and PQS and PMT-half-sharing (PHS) arrangements were implemented in order to obtain a suitable decoding. The packing fraction was 96.3% for asymmetric block and 95.5% for symmetric block. Both of the blocks have excellent decoding capability with all crystals clearly identified, 156 for asymmetric and 144 for symmetric and peak-to-valley ratio of 3.0 and 2.3 respectively. The average energy resolution was 14.2% for the asymmetric block and 13.1% for the symmetric block. Using a modified PQS geometry and asymmetric block design, we reduced the unused PMT region at detector panel edges, thereby increased the field-of-view and the overall detection sensitivity and minimized the undetected breast region near the chest wall. This detector design and using regular round PMT allowed building a lower-cost, high-resolution and high-sensitivity PEM camera. PMID:20485510

SCC500: next-generation infrared imaging camera core products with highly flexible architecture for unique camera designs

NASA Astrophysics Data System (ADS)

Rumbaugh, Roy N.; Grealish, Kevin; Kacir, Tom; Arsenault, Barry; Murphy, Robert H.; Miller, Scott

2003-09-01

A new 4th generation MicroIR architecture is introduced as the latest in the highly successful Standard Camera Core (SCC) series by BAE SYSTEMS to offer an infrared imaging engine with greatly reduced size, weight, power, and cost. The advanced SCC500 architecture provides great flexibility in configuration to include multiple resolutions, an industry standard Real Time Operating System (RTOS) for customer specific software application plug-ins, and a highly modular construction for unique physical and interface options. These microbolometer based camera cores offer outstanding and reliable performance over an extended operating temperature range to meet the demanding requirements of real-world environments. A highly integrated lens and shutter is included in the new SCC500 product enabling easy, drop-in camera designs for quick time-to-market product introductions.

[Diagnostic use of positron emission tomography in France: from the coincidence gamma-camera to mobile hybrid PET/CT devices].

PubMed

Talbot, Jean-Noël

2010-11-01

Positron emission tomography (PET) is a well-established medical imaging method. PET is increasingly used for diagnostic purposes, especially in oncology. The most widely used radiopharmaceutical is FDG, a glucose analogue. Other radiopharmaceuticals have recently been registered or are in development. We outline technical improvements of PET machines during more than a decade of clinical use in France. Even though image quality has improved considerably and PET-CT hybrid machines have emerged, spending per examination has remained remarkably constant. Replacement and maintenance costs have remained in the range of 170-190 Euros per examination since 1997, whether early CDET gamma cameras or the latest time-of-flight PET/CT devices are used. This is mainly due to shorter acquisition times and more efficient use of FDG New reimbursement rates for PET/CT are needed in France in order to favor regular acquisition of state-of-the-art devices. One major development is the coupling of PET and MR imaging.

Prototype of the Modular Equipment Transporter (MET)

NASA Technical Reports Server (NTRS)

1970-01-01

A prototype of the Modular Equipment Transporter (MET), nicknamed the 'Rickshaw' after its shape and method of propulsion. This equipment was used by the Apollo 14 astronauts during their geological and lunar surface simulation training in the Pinacate volcanic area of northwestern Sonora, Mexico. The Apollo 14 crew will be the first one to use the MET. It will be a portable workbench with a place for the lunar handtools and their carrier, three cameras, two sample container bags, a Special Environmental Sample Container, spare film magazines, and a Lunar Surface Penetrometer.

Drawings of the Modular Equipment Transporter and Hand Tool Carrier

NASA Image and Video Library

1970-10-12

S70-50762 (November 1970) --- A line drawing illustrating layout view of the modular equipment transporter (MET) and its equipment. A MET (or Rickshaw, as it has been nicknamed) will be used on the lunar surface for the first time during the Apollo 14 lunar landing mission. The Rickshaw will serve as a portable workbench with a place for the Apollo lunar hand tools (ALHT) and their carrier, three cameras, two sample container bags, a special environment sample container (SESC), a lunar portable magnetometer (LPM) and spare film magazines.

Design and implementation of modular home security system with short messaging system

NASA Astrophysics Data System (ADS)

Budijono, Santoso; Andrianto, Jeffri; Axis Novradin Noor, Muhammad

2014-03-01

Today we are living in 21st century where crime become increasing and everyone wants to secure they asset at their home. In that situation user must have system with advance technology so person do not worry when getting away from his home. It is therefore the purpose of this design to provide home security device, which send fast information to user GSM (Global System for Mobile) mobile device using SMS (Short Messaging System) and also activate - deactivate system by SMS. The Modular design of this Home Security System make expandable their capability by add more sensors on that system. Hardware of this system has been designed using microcontroller AT Mega 328, PIR (Passive Infra Red) motion sensor as the primary sensor for motion detection, camera for capturing images, GSM module for sending and receiving SMS and buzzer for alarm. For software this system using Arduino IDE for Arduino and Putty for testing connection programming in GSM module. This Home Security System can monitor home area that surrounding by PIR sensor and sending SMS, save images capture by camera, and make people panic by turn on the buzzer when trespassing surrounding area that detected by PIR sensor. The Modular Home Security System has been tested and succeed detect human movement.

Extended spectrum SWIR camera with user-accessible Dewar

NASA Astrophysics Data System (ADS)

Benapfl, Brendan; Miller, John Lester; Vemuri, Hari; Grein, Christoph; Sivananthan, Siva

2017-02-01

Episensors has developed a series of extended short wavelength infrared (eSWIR) cameras based on high-Cd concentration Hg1-xCdxTe absorbers. The cameras have a bandpass extending to 3 microns cutoff wavelength, opening new applications relative to traditional InGaAs-based cameras. Applications and uses are discussed and examples given. A liquid nitrogen pour-filled version was initially developed. This was followed by a compact Stirling-cooled version with detectors operating at 200 K. Each camera has unique sensitivity and performance characteristics. The cameras' size, weight and power specifications are presented along with images captured with band pass filters and eSWIR sources to demonstrate spectral response beyond 1.7 microns. The soft seal Dewars of the cameras are designed for accessibility, and can be opened and modified in a standard laboratory environment. This modular approach allows user flexibility for swapping internal components such as cold filters and cold stops. The core electronics of the Stirlingcooled camera are based on a single commercial field programmable gate array (FPGA) that also performs on-board non-uniformity corrections, bad pixel replacement, and directly drives any standard HDMI display.

Fiber optic TV direct

NASA Technical Reports Server (NTRS)

Kassak, John E.

1991-01-01

The objective of the operational television (OTV) technology was to develop a multiple camera system (up to 256 cameras) for NASA Kennedy installations where camera video, synchronization, control, and status data are transmitted bidirectionally via a single fiber cable at distances in excess of five miles. It is shown that the benefits (such as improved video performance, immunity from electromagnetic interference and radio frequency interference, elimination of repeater stations, and more system configuration flexibility) can be realized if application of the proven fiber optic transmission concept is used. The control system will marry the lens, pan and tilt, and camera control functions into a modular based Local Area Network (LAN) control network. Such a system does not exist commercially at present since the Television Broadcast Industry's current practice is to divorce the positional controls from the camera control system. The application software developed for this system will have direct applicability to similar systems in industry using LAN based control systems.

Nuclear medicine imaging system

DOEpatents

Bennett, Gerald W.; Brill, A. Bertrand; Bizais, Yves J.; Rowe, R. Wanda; Zubal, I. George

1986-01-07

A nuclear medicine imaging system having two large field of view scintillation cameras mounted on a rotatable gantry and being movable diametrically toward or away from each other is disclosed. In addition, each camera may be rotated about an axis perpendicular to the diameter of the gantry. The movement of the cameras allows the system to be used for a variety of studies, including positron annihilation, and conventional single photon emission, as well as static orthogonal dual multi-pinhole tomography. In orthogonal dual multi-pinhole tomography, each camera is fitted with a seven pinhole collimator to provide seven views from slightly different perspectives. By using two cameras at an angle to each other, improved sensitivity and depth resolution is achieved. The computer system and interface acquires and stores a broad range of information in list mode, including patient physiological data, energy data over the full range detected by the cameras, and the camera position. The list mode acquisition permits the study of attenuation as a result of Compton scatter, as well as studies involving the isolation and correlation of energy with a range of physiological conditions.

Nuclear medicine imaging system

DOEpatents

Bennett, Gerald W.; Brill, A. Bertrand; Bizais, Yves J. C.; Rowe, R. Wanda; Zubal, I. George

1986-01-01

A nuclear medicine imaging system having two large field of view scintillation cameras mounted on a rotatable gantry and being movable diametrically toward or away from each other is disclosed. In addition, each camera may be rotated about an axis perpendicular to the diameter of the gantry. The movement of the cameras allows the system to be used for a variety of studies, including positron annihilation, and conventional single photon emission, as well as static orthogonal dual multi-pinhole tomography. In orthogonal dual multi-pinhole tomography, each camera is fitted with a seven pinhole collimator to provide seven views from slightly different perspectives. By using two cameras at an angle to each other, improved sensitivity and depth resolution is achieved. The computer system and interface acquires and stores a broad range of information in list mode, including patient physiological data, energy data over the full range detected by the cameras, and the camera position. The list mode acquisition permits the study of attenuation as a result of Compton scatter, as well as studies involving the isolation and correlation of energy with a range of physiological conditions.

Microprocessor-controlled wide-range streak camera

NASA Astrophysics Data System (ADS)

Lewis, Amy E.; Hollabaugh, Craig

2006-08-01

Bechtel Nevada/NSTec recently announced deployment of their fifth generation streak camera. This camera incorporates many advanced features beyond those currently available for streak cameras. The arc-resistant driver includes a trigger lockout mechanism, actively monitors input trigger levels, and incorporates a high-voltage fault interrupter for user safety and tube protection. The camera is completely modular and may deflect over a variable full-sweep time of 15 nanoseconds to 500 microseconds. The camera design is compatible with both large- and small-format commercial tubes from several vendors. The embedded microprocessor offers Ethernet connectivity, and XML [extensible markup language]-based configuration management with non-volatile parameter storage using flash-based storage media. The camera's user interface is platform-independent (Microsoft Windows, Unix, Linux, Macintosh OSX) and is accessible using an AJAX [asynchronous Javascript and XML]-equipped modem browser, such as Internet Explorer 6, Firefox, or Safari. User interface operation requires no installation of client software or browser plug-in technology. Automation software can also access the camera configuration and control using HTTP [hypertext transfer protocol]. The software architecture supports multiple-simultaneous clients, multiple cameras, and multiple module access with a standard browser. The entire user interface can be customized.

Note: Tormenta: An open source Python-powered control software for camera based optical microscopy.

PubMed

Barabas, Federico M; Masullo, Luciano A; Stefani, Fernando D

2016-12-01

Until recently, PC control and synchronization of scientific instruments was only possible through closed-source expensive frameworks like National Instruments' LabVIEW. Nowadays, efficient cost-free alternatives are available in the context of a continuously growing community of open-source software developers. Here, we report on Tormenta, a modular open-source software for the control of camera-based optical microscopes. Tormenta is built on Python, works on multiple operating systems, and includes some key features for fluorescence nanoscopy based on single molecule localization.

Note: Tormenta: An open source Python-powered control software for camera based optical microscopy

NASA Astrophysics Data System (ADS)

Barabas, Federico M.; Masullo, Luciano A.; Stefani, Fernando D.

2016-12-01

Until recently, PC control and synchronization of scientific instruments was only possible through closed-source expensive frameworks like National Instruments' LabVIEW. Nowadays, efficient cost-free alternatives are available in the context of a continuously growing community of open-source software developers. Here, we report on Tormenta, a modular open-source software for the control of camera-based optical microscopes. Tormenta is built on Python, works on multiple operating systems, and includes some key features for fluorescence nanoscopy based on single molecule localization.

Status and Perspectives for a Slow Positron Beam Facility at the HH—NIPNE Bucharest

NASA Astrophysics Data System (ADS)

Constantin, Florin; Craciun, Liviu Stefan; Constantinescu, Olimpiu; Ghita, Ionica Alina; Ionescu, Cristina; Racolta, Petru Mihai; Straticiuc, Mihai; Vasilescu, Angela; Braic, Viorel; Zoita, Catalin; Kiss, Adrian; Bojin, Dionezie

2009-03-01

The development of a positron annihilation spectroscopy laboratory at the HH-NIPNE Bucharest-to be used for material studies and applications was started in the last 10 years. In the framework of a national research project extended over the last 3 years, was designed a low energy positron accelerator, as a high-vacuum dedicated beam line with two options: a 25 mCi 22NaCl source and in line with the NIPNE-cyclotron or a new intense compact cyclotron. The construction of the beam line was planned as a sequence of modules: source- moderator system; magnetical filter for fast positrons in order to select the positrons energies in the range 0.8-1 keV; a modular system for focusing, transport and acceleration of monoenergetic positrons in the energy range 0.8-50 keV and a CDBS analysis chamber. The moderator proposed—is tungsten as a foil of about 3 μm prepared at the Optoelectronics Institute were put into a thermal treatment vacuum chamber and bombarded with electrons from a 100 W electron gun After the treatment, they were tested for changes of elemental composition of the surface and structure at the Polytechnic University. The structure tests were performed on a DRON 3 M diffractometer, with a Co tube (λKα = 1.7903 A)—the angular regions studied were around 34° (1 0 0) and 69° (2 0 0). In the present time, the trajectories of the positron are going to be simulated with dedicated software (an ion and electron optics simulator). For the coincidence measurements (CDBS) set-up we used a home-made 22NaCl source, by separation without carrier from a metallic Mg target irradiated with 12 MeV protons and separated by columnar cation exchange. A home- made biparametric system for CDBS measurements will be reported, also.

Status and Perspectives for a Slow Positron Beam Facility at the HH-NIPNE Bucharest

NASA Astrophysics Data System (ADS)

Straticiuc, Mihai; Craciun, Liviu Stefan; Constantinescu, Olimpiu; Ghita, Ionica Alina; Ionescu, Cristina; Racolta, Petru Mihai; Vasilescu, Angela; Braic, Viorel; Zoita, Catalin; Kiss, Adrian; Bojin, Dionezie

2009-03-01

The development of a positron annihilation spectroscopy laboratory at the HH-NIPNE Bucharest-to be used for material studies and applications was started in the last 10 years. In the framework of a national research project extended over the last 3 years, was designed a low energy positron accelerator, as a high-vacuum dedicated beam line with two options: a 25 mCi 22NaCl source and in line with the NIPNE-cyclotron or a new intense compact cyclotron. The construction of the beam line was planned as a sequence of modules: source- moderator system; magnetical filter for fast positrons in order to select the positrons energies in the range 0.8-1 keV; a modular system for focusing, transport and acceleration of monoenergetic positrons in the energy range 0.8-50 keV and a CDBS analysis chamber. The moderator proposed-is tungsten as a foil of about 3 μm prepared at the Optoelectronics Institute were put into a thermal treatment vacuum chamber and bombarded with electrons from a 100 W electron gun After the treatment, they were tested for changes of elemental composition of the surface and structure at the Polytechnic University. The structure tests were performed on a DRON 3 M diffractometer, with a Co tube (λKα = 1.7903 A)-the angular regions studied were around 34° (1 0 0) and 69° (2 0 0). In the present time, the trajectories of the positron are going to be simulated with dedicated software (an ion and electron optics simulator). For the coincidence measurements (CDBS) set-up we used a home-made 22NaCl source, by separation without carrier from a metallic Mg target irradiated with 12 MeV protons and separated by columnar cation exchange. A home- made biparametric system for CDBS measurements will be reported, also.

Commander Brand shaves in front of forward middeck lockers

NASA Technical Reports Server (NTRS)

1982-01-01

Commander Brand, wearing shorts, shaves in front of forward middeck lockers using personal hygiene mirror assembly (assy). Open modular locker single tray assy, Field Sequential (FS) crew cabin camera, communications kit assy mini headset (HDST) and HDST interface unit (HIU), personal hygiene kit, and meal tray assemblies appear in view.

Robotic Welding and Inspection System

DOE Office of Scientific and Technical Information (OSTI.GOV)

H. B. Smartt; D. P. Pace; E. D. Larsen

2008-06-01

This paper presents a robotic system for GTA welding of lids on cylindrical vessels. The system consists of an articulated robot arm, a rotating positioner, end effectors for welding, grinding, ultrasonic and eddy current inspection. Features include weld viewing cameras, modular software, and text-based procedural files for process and motion trajectories.

An autonomous sensor module based on a legacy CCTV camera

NASA Astrophysics Data System (ADS)

Kent, P. J.; Faulkner, D. A. A.; Marshall, G. F.

2016-10-01

A UK MoD funded programme into autonomous sensors arrays (SAPIENT) has been developing new, highly capable sensor modules together with a scalable modular architecture for control and communication. As part of this system there is a desire to also utilise existing legacy sensors. The paper reports upon the development of a SAPIENT-compliant sensor module using a legacy Close-Circuit Television (CCTV) pan-tilt-zoom (PTZ) camera. The PTZ camera sensor provides three modes of operation. In the first mode, the camera is automatically slewed to acquire imagery of a specified scene area, e.g. to provide "eyes-on" confirmation for a human operator or for forensic purposes. In the second mode, the camera is directed to monitor an area of interest, with zoom level automatically optimized for human detection at the appropriate range. Open source algorithms (using OpenCV) are used to automatically detect pedestrians; their real world positions are estimated and communicated back to the SAPIENT central fusion system. In the third mode of operation a "follow" mode is implemented where the camera maintains the detected person within the camera field-of-view without requiring an end-user to directly control the camera with a joystick.

Microprocessor-controlled, wide-range streak camera

DOE Office of Scientific and Technical Information (OSTI.GOV)

Amy E. Lewis, Craig Hollabaugh

Bechtel Nevada/NSTec recently announced deployment of their fifth generation streak camera. This camera incorporates many advanced features beyond those currently available for streak cameras. The arc-resistant driver includes a trigger lockout mechanism, actively monitors input trigger levels, and incorporates a high-voltage fault interrupter for user safety and tube protection. The camera is completely modular and may deflect over a variable full-sweep time of 15 nanoseconds to 500 microseconds. The camera design is compatible with both large- and small-format commercial tubes from several vendors. The embedded microprocessor offers Ethernet connectivity, and XML [extensible markup language]-based configuration management with non-volatile parameter storagemore » using flash-based storage media. The camera’s user interface is platform-independent (Microsoft Windows, Unix, Linux, Macintosh OSX) and is accessible using an AJAX [asynchronous Javascript and XML]-equipped modem browser, such as Internet Explorer 6, Firefox, or Safari. User interface operation requires no installation of client software or browser plug-in technology. Automation software can also access the camera configuration and control using HTTP [hypertext transfer protocol]. The software architecture supports multiple-simultaneous clients, multiple cameras, and multiple module access with a standard browser. The entire user interface can be customized.« less

Inter-subject FDG PET Brain Networks Exhibit Multi-scale Community Structure with Different Normalization Techniques.

PubMed

Sperry, Megan M; Kartha, Sonia; Granquist, Eric J; Winkelstein, Beth A

2018-07-01

Inter-subject networks are used to model correlations between brain regions and are particularly useful for metabolic imaging techniques, like 18F-2-deoxy-2-(18F)fluoro-D-glucose (FDG) positron emission tomography (PET). Since FDG PET typically produces a single image, correlations cannot be calculated over time. Little focus has been placed on the basic properties of inter-subject networks and if they are affected by group size and image normalization. FDG PET images were acquired from rats (n = 18), normalized by whole brain, visual cortex, or cerebellar FDG uptake, and used to construct correlation matrices. Group size effects on network stability were investigated by systematically adding rats and evaluating local network connectivity (node strength and clustering coefficient). Modularity and community structure were also evaluated in the differently normalized networks to assess meso-scale network relationships. Local network properties are stable regardless of normalization region for groups of at least 10. Whole brain-normalized networks are more modular than visual cortex- or cerebellum-normalized network (p < 0.00001); however, community structure is similar at network resolutions where modularity differs most between brain and randomized networks. Hierarchical analysis reveals consistent modules at different scales and clustering of spatially-proximate brain regions. Findings suggest inter-subject FDG PET networks are stable for reasonable group sizes and exhibit multi-scale modularity.

Modularized compact positron emission tomography detector for rapid system development

PubMed Central

Xi, Daoming; Liu, Xiang; Zeng, Chen; Liu, Wei; Li, Yanzhao; Hua, Yuexuan; Mei, Xiongze; Kim, Heejong; Xiao, Peng; Kao, Chien-Min; Xie, Qingguo

2016-01-01

Abstract. We report the development of a modularized compact positron emission tomography (PET) detector that outputs serial streams of digital samples of PET event pulses via an Ethernet interface using the UDP/IP protocol to enable rapid configuration of a PET system by connecting multiple such detectors via a network switch to a computer. Presently, the detector is 76  mm×50  mm×55  mm in extent (excluding I/O connectors) and contains an 18×12 array of 4.2×4.2×20  mm3 one-to-one coupled lutetium-yttrium oxyorthosilicate/silicon photomultiplier pixels. It employs cross-wire and stripline readouts to merge the outputs of the 216 detector pixels to 24 channels. Signals at these channels are sampled using a built-in 24-ch, 4-level field programmable gate arrays-only multivoltage threshold digitizer. In the computer, software programs are implemented to analyze the digital samples to extract event information and to perform energy qualification and coincidence filtering. We have developed two such detectors. We show that all their pixels can be accurately discriminated and measure a crystal-level energy resolution of 14.4% to 19.4% and a detector-level coincidence time resolution of 1.67 ns FWHM. Preliminary imaging results suggests that a PET system based on the detectors can achieve an image resolution of ∼1.6  mm. PMID:28018941

Design and Modular Construction of A Polymeric Nanoparticle for Targeted Atherosclerosis Positron Emission Tomography Imaging: A Story of 25% 64Cu-CANF-Comb

PubMed Central

Woodard, Pamela K.; Liu, Yongjian; Pressly, Eric D.; Luehmann, Hannah P.; Detering, Lisa; Sultan, Deborah; Laforest, Richard; McGrath, Alaina J.; Gropler, Robert J.; Hawker, Craig J.

2016-01-01

Purpose To assess the physicochemical properties, pharmacokinetic profiles, and in vivo positron emission tomography (PET) imaging of natriuretic peptide clearance receptors (NPRC) expressed on atherosclerotic plaque of a series of targeted, polymeric nanoparticles. Methods To control their structure, non-targeted and targeted polymeric (comb) nanoparticles, conjugated with various amounts of c-atrial natriuretic peptide (CANF, 0, 5, 10 and 25%), were synthesized by controlled and modular chemistry. In vivo pharmacokinetic evaluation of these nanoparticles was performed in wildtype (WT) C57BL/6 mice after 64Cu radiolabeling. PET imaging was performed on an apolipoprotein E–deficient (ApoE−/−) mouse atherosclerosis model to assess the NPRC targeting efficiency. For comparison, an in vivo blood metabolism study was carried out in WT mice. Results All three 64Cu-CANF-comb nanoparticles showed improved biodistribution profiles, including significantly reduced accumulation in both liver and spleen, compared to the non-targeted 64Cu-comb. Of the three nanoparticles, the 25% 64Cu-CANF-comb demonstrated the best NPRC targeting specificity and sensitivity in ApoE−/− mice. Metabolism studies showed that the radiolabeled CANF-comb was stable in blood up to 9 days. Histopathological analyses confirmed the up-regulation of NPRC along the progression of atherosclerosis. Conclusion The 25% 64Cu-CANF-comb demonstrated its potential as a PET imaging agent to detect atherosclerosis progression and status. PMID:27286872

Gyrocopter-Based Remote Sensing Platform

NASA Astrophysics Data System (ADS)

Weber, I.; Jenal, A.; Kneer, C.; Bongartz, J.

2015-04-01

In this paper the development of a lightweight and highly modularized airborne sensor platform for remote sensing applications utilizing a gyrocopter as a carrier platform is described. The current sensor configuration consists of a high resolution DSLR camera for VIS-RGB recordings. As a second sensor modality, a snapshot hyperspectral camera was integrated in the aircraft. Moreover a custom-developed thermal imaging system composed of a VIS-PAN camera and a LWIR-camera is used for aerial recordings in the thermal infrared range. Furthermore another custom-developed highly flexible imaging system for high resolution multispectral image acquisition with up to six spectral bands in the VIS-NIR range is presented. The performance of the overall system was tested during several flights with all sensor modalities and the precalculated demands with respect to spatial resolution and reliability were validated. The collected data sets were georeferenced, georectified, orthorectified and then stitched to mosaics.

A modular wireless in vivo surgical robot with multiple surgical applications.

PubMed

Hawks, Jeff A; Rentschler, Mark E; Farritor, Shane; Oleynikov, Dmitry; Platt, Stephen R

2009-01-01

The use of miniature in vivo robots that fit entirely inside the peritoneal cavity represents a novel approach to laparoscopic surgery. Previous work demonstrates that both mobile and fixed-based robots can successfully operate inside the abdominal cavity. A modular wireless mobile platform has also been developed to provide surgical vision and task assistance. This paper presents an overview of recent test results of several possible surgical applications that can be accommodated by this modular platform. Applications such as a biopsy grasper, stapler and clamp, video camera, and physiological sensors have been integrated into the wireless platform and tested in vivo in a porcine model. The modular platform facilitates rapid development and conversion from one type of surgical task assistance to another. These self-contained surgical devices are much more transportable and much lower in cost than current robotic surgical assistants. These devices could ultimately be carried and deployed by non-medical personnel at the site of an injury. A remotely located surgeon could use these robots to provide critical first response medical intervention.

Silicon detectors for combined MR-PET and MR-SPECT imaging

NASA Astrophysics Data System (ADS)

Studen, A.; Brzezinski, K.; Chesi, E.; Cindro, V.; Clinthorne, N. H.; Cochran, E.; Grošičar, B.; Grkovski, M.; Honscheid, K.; Kagan, H.; Lacasta, C.; Llosa, G.; Mikuž, M.; Stankova, V.; Weilhammer, P.; Žontar, D.

2013-02-01

Silicon based devices can extend PET-MR and SPECT-MR imaging to applications, where their advantages in performance outweigh benefits of high statistical counts. Silicon is in many ways an excellent detector material with numerous advantages, among others: excellent energy and spatial resolution, mature processing technology, large signal to noise ratio, relatively low price, availability, versatility and malleability. The signal in silicon is also immune to effects of magnetic field at the level normally used in MR devices. Tests in fields up to 7 T were performed in a study to determine effects of magnetic field on positron range in a silicon PET device. The curvature of positron tracks in direction perpendicular to the field's orientation shortens the distance between emission and annihilation point of the positron. The effect can be fully appreciated for a rotation of the sample for a fixed field direction, compressing range in all dimensions. A popular Ga-68 source was used showing a factor of 2 improvement in image noise compared to zero field operation. There was also a little increase in noise as the reconstructed resolution varied between 2.5 and 1.5 mm. A speculative applications can be recognized in both emission modalities, SPECT and PET. Compton camera is a subspecies of SPECT, where a silicon based scatter as a MR compatible part could inserted into the MR bore and the secondary detector could operate in less constrained environment away from the magnet. Introducing a Compton camera also relaxes requirements of the radiotracers used, extending the range of conceivable photon energies beyond 140.5 keV of the Tc-99m. In PET, one could exploit the compressed sub-millimeter range of positrons in the magnetic field. To exploit the advantage, detectors with spatial resolution commensurate to the effect must be used with silicon being an excellent candidate. Measurements performed outside of the MR achieving spatial resolution below 1 mm are reported.

Commander Young removes CAP from FDF stowage locker on middeck

NASA Technical Reports Server (NTRS)

1981-01-01

Commander Young removes Crew Activity Plans (CAP) from Flight Data File (FD/FDF) modular stowage locker single tray assembly located in forward middeck locker MF28E. Window shade and filter kit on port side bulkhead and potable water tank on middeck floor appear in view. Photo was taken by Pilot Crippen with a 35mm camera.

A new scalable modular data acquisition system for SPECT (PET)

NASA Astrophysics Data System (ADS)

Stenstrom, P.; Rillbert, A.; Bergquist, M.; Habte, F.; Bohm, C.; Larsson, S. A.

1998-06-01

Describes a modular decentralized data acquisition system that continuously samples shaped PMT pulses from a SPECT detector. The pulse waveform data are used by signal processors to accurately reconstruct amplitude and time for each scintillation event. Data acquisition for a PMT channel is triggered in two alternative ways, either when its own signal exceeds a selected digital threshold, or when it receives a trigger pulse from one of its neighboring PMTs. The triggered region is restricted to seven, thirteen or nineteen neighboring PMT channels. Each acquisition module supports three PMT channels and connects to all other modules and a reconstruction computer via Firewire to cover the 72 channels in the Stockholm University/Karolinska Hospital cylindrical SPECT camera.

Scalable software architecture for on-line multi-camera video processing

NASA Astrophysics Data System (ADS)

Camplani, Massimo; Salgado, Luis

2011-03-01

In this paper we present a scalable software architecture for on-line multi-camera video processing, that guarantees a good trade off between computational power, scalability and flexibility. The software system is modular and its main blocks are the Processing Units (PUs), and the Central Unit. The Central Unit works as a supervisor of the running PUs and each PU manages the acquisition phase and the processing phase. Furthermore, an approach to easily parallelize the desired processing application has been presented. In this paper, as case study, we apply the proposed software architecture to a multi-camera system in order to efficiently manage multiple 2D object detection modules in a real-time scenario. System performance has been evaluated under different load conditions such as number of cameras and image sizes. The results show that the software architecture scales well with the number of camera and can easily works with different image formats respecting the real time constraints. Moreover, the parallelization approach can be used in order to speed up the processing tasks with a low level of overhead.

Accuracy Analysis for Automatic Orientation of a Tumbling Oblique Viewing Sensor System

NASA Astrophysics Data System (ADS)

Stebner, K.; Wieden, A.

2014-03-01

Dynamic camera systems with moving parts are difficult to handle in photogrammetric workflow, because it is not ensured that the dynamics are constant over the recording period. Minimum changes of the camera's orientation greatly influence the projection of oblique images. In this publication these effects - originating from the kinematic chain of a dynamic camera system - are analysed and validated. A member of the Modular Airborne Camera System family - MACS-TumbleCam - consisting of a vertical viewing and a tumbling oblique camera was used for this investigation. Focus is on dynamic geometric modeling and the stability of the kinematic chain. To validate the experimental findings, the determined parameters are applied to the exterior orientation of an actual aerial image acquisition campaign using MACS-TumbleCam. The quality of the parameters is sufficient for direct georeferencing of oblique image data from the orientation information of a synchronously captured vertical image dataset. Relative accuracy for the oblique data set ranges from 1.5 pixels when using all images of the image block to 0.3 pixels when using only adjacent images.

ATTICA family of thermal cameras in submarine applications

NASA Astrophysics Data System (ADS)

Kuerbitz, Gunther; Fritze, Joerg; Hoefft, Jens-Rainer; Ruf, Berthold

2001-10-01

Optronics Mast Systems (US: Photonics Mast Systems) are electro-optical devices which enable a submarine crew to observe the scenery above water during dive. Unlike classical submarine periscopes they are non-hull-penetrating and therefore have no direct viewing capability. Typically they have electro-optical cameras both for the visual and for an IR spectral band with panoramic view and a stabilized line of sight. They can optionally be equipped with laser range- finders, antennas, etc. The brand name ATTICA (Advanced Two- dimensional Thermal Imager with CMOS-Array) characterizes a family of thermal cameras using focal-plane-array (FPA) detectors which can be tailored to a variety of requirements. The modular design of the ATTICA components allows the use of various detectors (InSb, CMT 3...5 μm , CMT 7...11 μm ) for specific applications. By means of a microscanner ATTICA cameras achieve full standard TV resolution using detectors with only 288 X 384 (US:240 X 320) detector elements. A typical requirement for Optronics-Mast Systems is a Quick- Look-Around capability. For FPA cameras this implies the need for a 'descan' module which can be incorporated in the ATTICA cameras without complications.

Non-invasive imaging and cellular tracking of pulmonary emboli by near-infrared fluorescence and positron-emission tomography

PubMed Central

Page, Michael J.; Lourenço, André L.; David, Tovo; LeBeau, Aaron M.; Cattaruzza, Fiore; Castro, Helena C.; VanBrocklin, Henry F.; Coughlin, Shaun R.; Craik, Charles S.

2015-01-01

Functional imaging of proteolytic activity is an emerging strategy to quantify disease and response to therapy at the molecular level. We present a new peptide-based imaging probe technology that advances these goals by exploiting enzymatic activity to deposit probes labelled with near-infrared (NIR) fluorophores or radioisotopes in cell membranes of disease-associated proteolysis. This strategy allows for non-invasive detection of protease activity in vivo and ex vivo by tracking deposited probes in tissues. We demonstrate non-invasive detection of thrombin generation in a murine model of pulmonary embolism using our protease-activated peptide probes in microscopic clots within the lungs with NIR fluorescence optical imaging and positron-emission tomography. Thrombin activity is imaged deep in tissue and tracked predominantly to platelets within the lumen of blood vessels. The modular design of our probes allows for facile investigation of other proteases, and their contributions to disease by tailoring the protease activation and cell-binding elements. PMID:26423607

Uncooled microbolometer sensors for unattended applications

NASA Astrophysics Data System (ADS)

Kohin, Margaret; Miller, James E.; Leary, Arthur R.; Backer, Brian S.; Swift, William; Aston, Peter

2003-09-01

BAE SYSTEMS has been developing and producing uncooled microbolometer sensors since 1995. Recently, uncooled sensors have been used on Pointer Unattended Aerial Vehicles and considered for several unattended sensor applications including DARPA Micro-Internetted Unattended Ground Sensors (MIUGS), Army Modular Acoustic Imaging Sensors (MAIS), and Redeployable Unattended Ground Sensors (R-UGS). This paper describes recent breakthrough uncooled sensor performance at BAE SYSTEMS and how this improved performance has been applied to a new Standard Camera Core (SCC) that is ideal for these unattended applications. Video imagery from a BAE SYSTEMS 640x480 imaging camera flown in a Pointer UAV is provided. Recent performance results are also provided.

International Congress on High-Speed Photography and Photonics, 19th, Cambridge, England, Sept. 16-21, 1990, Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garfield, B.R.; Rendell, J.T.

1991-01-01

The present conference discusses the application of schlieren photography in industry, laser fiber-optic high speed photography, holographic visualization of hypervelocity explosions, sub-100-picosec X-ray grating cameras, flash soft X-radiography, a novel approach to synchroballistic photography, a programmable image converter framing camera, high speed readout CCDs, an ultrafast optomechanical camera, a femtosec streak tube, a modular streak camera for laser ranging, and human-movement analysis with real-time imaging. Also discussed are high-speed photography of high-resolution moire patterns, a 2D electron-bombarded CCD readout for picosec electrooptical data, laser-generated plasma X-ray diagnostics, 3D shape restoration with virtual grating phase detection, Cu vapor lasers for highmore » speed photography, a two-frequency picosec laser with electrooptical feedback, the conversion of schlieren systems to high speed interferometers, laser-induced cavitation bubbles, stereo holographic cinematography, a gatable photonic detector, and laser generation of Stoneley waves at liquid-solid boundaries.« less

BAE Systems' 17μm LWIR camera core for civil, commercial, and military applications

NASA Astrophysics Data System (ADS)

Lee, Jeffrey; Rodriguez, Christian; Blackwell, Richard

2013-06-01

Seventeen (17) µm pixel Long Wave Infrared (LWIR) Sensors based on vanadium oxide (VOx) micro-bolometers have been in full rate production at BAE Systems' Night Vision Sensors facility in Lexington, MA for the past five years.[1] We introduce here a commercial camera core product, the Airia-MTM imaging module, in a VGA format that reads out in 30 and 60Hz progressive modes. The camera core is architected to conserve power with all digital interfaces from the readout integrated circuit through video output. The architecture enables a variety of input/output interfaces including Camera Link, USB 2.0, micro-display drivers and optional RS-170 analog output supporting legacy systems. The modular board architecture of the electronics facilitates hardware upgrades allow us to capitalize on the latest high performance low power electronics developed for the mobile phones. Software and firmware is field upgradeable through a USB 2.0 port. The USB port also gives users access to up to 100 digitally stored (lossless) images.

Standoff aircraft IR characterization with ABB dual-band hyper spectral imager

NASA Astrophysics Data System (ADS)

Prel, Florent; Moreau, Louis; Lantagne, Stéphane; Bullis, Ritchie D.; Roy, Claude; Vallières, Christian; Levesque, Luc

2012-09-01

Remote sensing infrared characterization of rapidly evolving events generally involves the combination of a spectro-radiometer and infrared camera(s) as separated instruments. Time synchronization, spatial coregistration, consistent radiometric calibration and managing several systems are important challenges to overcome; they complicate the target infrared characterization data processing and increase the sources of errors affecting the final radiometric accuracy. MR-i is a dual-band Hyperspectal imaging spectro-radiometer, that combines two 256 x 256 pixels infrared cameras and an infrared spectro-radiometer into one single instrument. This field instrument generates spectral datacubes in the MWIR and LWIR. It is designed to acquire the spectral signatures of rapidly evolving events. The design is modular. The spectrometer has two output ports configured with two simultaneously operated cameras to either widen the spectral coverage or to increase the dynamic range of the measured amplitudes. Various telescope options are available for the input port. Recent platform developments and field trial measurements performances will be presented for a system configuration dedicated to the characterization of airborne targets.

Recording the synchrotron radiation by a picosecond streak camera for bunch diagnostics in cyclic accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vereshchagin, A K; Vorob'ev, N S; Gornostaev, P B

2016-02-28

A PS-1/S1 picosecond streak camera with a linear sweep is used to measure temporal characteristics of synchrotron radiation pulses on a damping ring (DR) at the Budker Institute of Nuclear Physics (BINP) of the Siberian Branch of the Russian Academy of Sciences (Novosibirsk). The data obtained allow a conclusion as to the formation processes of electron bunches and their 'quality' in the DR after injection from the linear accelerator. The expediency of employing the streak camera as a part of an optical diagnostic accelerator complex for adjusting the injection from a linear accelerator is shown. Discussed is the issue ofmore » designing a new-generation dissector with a time resolution up to a few picoseconds, which would allow implementation of a continuous bunch monitoring in the DR during mutual work with the electron-positron colliders at the BINP. (acoustooptics)« less

First full-beam PET acquisitions in proton therapy with a modular dual-head dedicated system

NASA Astrophysics Data System (ADS)

Sportelli, G.; Belcari, N.; Camarlinghi, N.; Cirrone, G. A. P.; Cuttone, G.; Ferretti, S.; Kraan, A.; Ortuño, J. E.; Romano, F.; Santos, A.; Straub, K.; Tramontana, A.; Del Guerra, A.; Rosso, V.

2014-01-01

During particle therapy irradiation, positron emitters with half-lives ranging from 2 to 20 min are generated from nuclear processes. The half-lives are such that it is possible either to detect the positron signal in the treatment room using an in-beam positron emission tomography (PET) system, right after the irradiation, or to quickly transfer the patient to a close PET/CT scanner. Since the activity distribution is spatially correlated with the dose, it is possible to use PET imaging as an indirect method to assure the quality of the dose delivery. In this work, we present a new dedicated PET system able to operate in-beam. The PET apparatus consists in two 10 cm × 10 cm detector heads. Each detector is composed of four scintillating matrices of 23 × 23 LYSO crystals. The crystal size is 1.9 mm × 1.9 mm × 16 mm. Each scintillation matrix is read out independently with a modularized acquisition system. The distance between the two opposing detector heads was set to 20 cm. The system has very low dead time per detector area and a 3 ns coincidence window, which is capable to sustain high single count rates and to keep the random counts relatively low. This allows a new full-beam monitoring modality that includes data acquisition also while the beam is on. The PET system was tested during the irradiation at the CATANA (INFN, Catania, Italy) cyclotron-based proton therapy facility. Four acquisitions with different doses and dose rates were analysed. In all cases the random to total coincidences ratio was equal or less than 25%. For each measurement we estimated the accuracy and precision of the activity range on a set of voxel lines within an irradiated PMMA phantom. Results show that the inclusion of data acquired during the irradiation, referred to as beam-on data, improves both the precision and accuracy of the range measurement with respect to data acquired only after irradiation. Beam-on data alone are enough to give precisions better than 1 mm when at least 5 Gy are delivered.

Function-based design process for an intelligent ground vehicle vision system

NASA Astrophysics Data System (ADS)

Nagel, Robert L.; Perry, Kenneth L.; Stone, Robert B.; McAdams, Daniel A.

2010-10-01

An engineering design framework for an autonomous ground vehicle vision system is discussed. We present both the conceptual and physical design by following the design process, development and testing of an intelligent ground vehicle vision system constructed for the 2008 Intelligent Ground Vehicle Competition. During conceptual design, the requirements for the vision system are explored via functional and process analysis considering the flows into the vehicle and the transformations of those flows. The conceptual design phase concludes with a vision system design that is modular in both hardware and software and is based on a laser range finder and camera for visual perception. During physical design, prototypes are developed and tested independently, following the modular interfaces identified during conceptual design. Prototype models, once functional, are implemented into the final design. The final vision system design uses a ray-casting algorithm to process camera and laser range finder data and identify potential paths. The ray-casting algorithm is a single thread of the robot's multithreaded application. Other threads control motion, provide feedback, and process sensory data. Once integrated, both hardware and software testing are performed on the robot. We discuss the robot's performance and the lessons learned.

Modular optical topometric sensor for 3D acquisition of human body surfaces and long-term monitoring of variations.

PubMed

Bischoff, Guido; Böröcz, Zoltan; Proll, Christian; Kleinheinz, Johannes; von Bally, Gert; Dirksen, Dieter

2007-08-01

Optical topometric 3D sensors such as laser scanners and fringe projection systems allow detailed digital acquisition of human body surfaces. For many medical applications, however, not only the current shape is important, but also its changes, e.g., in the course of surgical treatment. In such cases, time delays of several months between subsequent measurements frequently occur. A modular 3D coordinate measuring system based on the fringe projection technique is presented that allows 3D coordinate acquisition including calibrated color information, as well as the detection and visualization of deviations between subsequent measurements. In addition, parameters describing the symmetry of body structures are determined. The quantitative results of the analysis may be used as a basis for objective documentation of surgical therapy. The system is designed in a modular way, and thus, depending on the object of investigation, two or three cameras with different capabilities in terms of resolution and color reproduction can be utilized to optimize the set-up.

Feasibility of a high-speed gamma-camera design using the high-yield-pileup-event-recovery method.

PubMed

Wong, W H; Li, H; Uribe, J; Baghaei, H; Wang, Y; Yokoyama, S

2001-04-01

Higher count-rate gamma cameras than are currently used are needed if the technology is to fulfill its promise in positron coincidence imaging, radionuclide therapy dosimetry imaging, and cardiac first-pass imaging. The present single-crystal design coupled with conventional detector electronics and the traditional Anger-positioning algorithm hinder higher count-rate imaging because of the pileup of gamma-ray signals in the detector and electronics. At an interaction rate of 2 million events per second, the fraction of nonpileup events is < 20% of the total incident events. Hence, the recovery of pileup events can significantly increase the count-rate capability, increase the yield of imaging photons, and minimize image artifacts associated with pileups. A new technology to significantly enhance the performance of gamma cameras in this area is introduced. We introduce a new electronic design called high-yield-pileup-event-recovery (HYPER) electronics for processing the detector signal in gamma cameras so that the individual gamma energies and positions of pileup events, including multiple pileups, can be resolved and recovered despite the mixing of signals. To illustrate the feasibility of the design concept, we have developed a small gamma-camera prototype with the HYPER-Anger electronics. The camera has a 10 x 10 x 1 cm NaI(Tl) crystal with four photomultipliers. Hot-spot and line sources with very high 99mTc activities were imaged. The phantoms were imaged continuously from 60,000 to 3,500,000 counts per second to illustrate the efficacy of the method as a function of counting rates. At 2-3 million events per second, all phantoms were imaged with little distortion, pileup, and dead-time loss. At these counting rates, multiple pileup events (> or = 3 events piling together) were the predominate occurrences, and the HYPER circuit functioned well to resolve and recover these events. The full width at half maximum of the line-spread function at 3,000,000 counts per second was 1.6 times that at 60,000 counts per second. This feasibility study showed that the HYPER electronic concept works; it can significantly increase the count-rate capability and dose efficiency of gamma cameras. In a larger clinical camera, multiple HYPER-Anger circuits may be implemented to further improve the imaging counting rates that we have shown by multiple times. This technology would facilitate the use of gamma cameras for radionuclide therapy dosimetry imaging, cardiac first-pass imaging, and positron coincidence imaging and the simultaneous acquisition of transmission and emission data using different isotopes with less cross-contamination between transmission and emission data.

Modular Scanning Confocal Microscope with Digital Image Processing.

PubMed

Ye, Xianjun; McCluskey, Matthew D

2016-01-01

In conventional confocal microscopy, a physical pinhole is placed at the image plane prior to the detector to limit the observation volume. In this work, we present a modular design of a scanning confocal microscope which uses a CCD camera to replace the physical pinhole for materials science applications. Experimental scans were performed on a microscope resolution target, a semiconductor chip carrier, and a piece of etched silicon wafer. The data collected by the CCD were processed to yield images of the specimen. By selecting effective pixels in the recorded CCD images, a virtual pinhole is created. By analyzing the image moments of the imaging data, a lateral resolution enhancement is achieved by using a 20 × / NA = 0.4 microscope objective at 532 nm laser wavelength.

Performance of the Tachyon Time-of-Flight PET Camera

NASA Astrophysics Data System (ADS)

Peng, Q.; Choong, W.-S.; Vu, C.; Huber, J. S.; Janecek, M.; Wilson, D.; Huesman, R. H.; Qi, Jinyi; Zhou, Jian; Moses, W. W.

2015-02-01

We have constructed and characterized a time-of-flight Positron Emission Tomography (TOF PET) camera called the Tachyon. The Tachyon is a single-ring Lutetium Oxyorthosilicate (LSO) based camera designed to obtain significantly better timing resolution than the 550 ps found in present commercial TOF cameras, in order to quantify the benefit of improved TOF resolution for clinically relevant tasks. The Tachyon's detector module is optimized for timing by coupling the 6.15 ×25 mm2 side of 6.15 ×6.15 ×25 mm3 LSO scintillator crystals onto a 1-inch diameter Hamamatsu R-9800 PMT with a super-bialkali photocathode. We characterized the camera according to the NEMA NU 2-2012 standard, measuring the energy resolution, timing resolution, spatial resolution, noise equivalent count rates and sensitivity. The Tachyon achieved a coincidence timing resolution of 314 ps +/- 20 ps FWHM over all crystal-crystal combinations. Experiments were performed with the NEMA body phantom to assess the imaging performance improvement over non-TOF PET. The results show that at a matched contrast, incorporating 314 ps TOF reduces the standard deviation of the contrast by a factor of about 2.3.

Performance of the Tachyon Time-of-Flight PET Camera.

PubMed

Peng, Q; Choong, W-S; Vu, C; Huber, J S; Janecek, M; Wilson, D; Huesman, R H; Qi, Jinyi; Zhou, Jian; Moses, W W

2015-02-01

We have constructed and characterized a time-of-flight Positron Emission Tomography (TOF PET) camera called the Tachyon. The Tachyon is a single-ring Lutetium Oxyorthosilicate (LSO) based camera designed to obtain significantly better timing resolution than the ~ 550 ps found in present commercial TOF cameras, in order to quantify the benefit of improved TOF resolution for clinically relevant tasks. The Tachyon's detector module is optimized for timing by coupling the 6.15 × 25 mm 2 side of 6.15 × 6.15 × 25 mm 3 LSO scintillator crystals onto a 1-inch diameter Hamamatsu R-9800 PMT with a super-bialkali photocathode. We characterized the camera according to the NEMA NU 2-2012 standard, measuring the energy resolution, timing resolution, spatial resolution, noise equivalent count rates and sensitivity. The Tachyon achieved a coincidence timing resolution of 314 ps +/- ps FWHM over all crystal-crystal combinations. Experiments were performed with the NEMA body phantom to assess the imaging performance improvement over non-TOF PET. The results show that at a matched contrast, incorporating 314 ps TOF reduces the standard deviation of the contrast by a factor of about 2.3.

Performance of the Tachyon Time-of-Flight PET Camera

PubMed Central

Peng, Q.; Choong, W.-S.; Vu, C.; Huber, J. S.; Janecek, M.; Wilson, D.; Huesman, R. H.; Qi, Jinyi; Zhou, Jian; Moses, W. W.

2015-01-01

We have constructed and characterized a time-of-flight Positron Emission Tomography (TOF PET) camera called the Tachyon. The Tachyon is a single-ring Lutetium Oxyorthosilicate (LSO) based camera designed to obtain significantly better timing resolution than the ~ 550 ps found in present commercial TOF cameras, in order to quantify the benefit of improved TOF resolution for clinically relevant tasks. The Tachyon’s detector module is optimized for timing by coupling the 6.15 × 25 mm2 side of 6.15 × 6.15 × 25 mm3 LSO scintillator crystals onto a 1-inch diameter Hamamatsu R-9800 PMT with a super-bialkali photocathode. We characterized the camera according to the NEMA NU 2-2012 standard, measuring the energy resolution, timing resolution, spatial resolution, noise equivalent count rates and sensitivity. The Tachyon achieved a coincidence timing resolution of 314 ps +/− ps FWHM over all crystal-crystal combinations. Experiments were performed with the NEMA body phantom to assess the imaging performance improvement over non-TOF PET. The results show that at a matched contrast, incorporating 314 ps TOF reduces the standard deviation of the contrast by a factor of about 2.3. PMID:26594057

Performance of the Tachyon Time-of-Flight PET Camera

DOE PAGES

Peng, Q.; Choong, W. -S.; Vu, C.; ...

2015-01-23

We have constructed and characterized a time-of-flight Positron Emission Tomography (TOF PET) camera called the Tachyon. The Tachyon is a single-ring Lutetium Oxyorthosilicate (LSO) based camera designed to obtain significantly better timing resolution than the ~ 550 ps found in present commercial TOF cameras, in order to quantify the benefit of improved TOF resolution for clinically relevant tasks. The Tachyon's detector module is optimized for timing by coupling the 6.15 ×25 mm 2 side of 6.15 ×6.15 ×25 mm 3 LSO scintillator crystals onto a 1-inch diameter Hamamatsu R-9800 PMT with a super-bialkali photocathode. We characterized the camera according tomore » the NEMA NU 2-2012 standard, measuring the energy resolution, timing resolution, spatial resolution, noise equivalent count rates and sensitivity. The Tachyon achieved a coincidence timing resolution of 314 ps +/- 20 ps FWHM over all crystal-crystal combinations. Experiments were performed with the NEMA body phantom to assess the imaging performance improvement over non-TOF PET. We find that the results show that at a matched contrast, incorporating 314 ps TOF reduces the standard deviation of the contrast by a factor of about 2.3.« less

N-(/sup 11/C)-methyl-p-substituted phentermine analogs as potential brain blood flow agents for positron tomography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kizuka, H.; Elmaleh, D.R.; Boudreaux, G.J.

The addition of a methyl group to the ..cap alpha..-position of amphetamine increases both the lipophilicity of the agent and its resistance to metabolism by monoamine oxidase. In addition, since tritium substituted phenteramine analog studies suggested that the p-halo phentermines had a greater concentration in the brain and prolonged retention time, the authors evaluated the biological behavior of positron labeled ..cap alpha..-methylamphetamine (phenteramine) in rats, dogs and monkeys. The N-(/sup 11/C) methyl analogs of p-chloro (I) and p-fluoro (II) phentermines were prepared by methylation of their primary amines using /sup 11/Ch/sub 3/I. Biodistribution studies in rats shows brain uptake ismore » in the range of 1% dose/gr at 5 and 15 min for both agents. The activity in blood and eyes is low. Sequential images of the dogs' brain over 1 hour revealed a clearance of <15%. Images of the monkey brain were also obtained using a MGH positron camera PCR-I.« less

Dual-Modality PET/Ultrasound imaging of the Prostate

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huber, Jennifer S.; Moses, William W.; Pouliot, Jean

2005-11-11

Functional imaging with positron emission tomography (PET)will detect malignant tumors in the prostate and/or prostate bed, as well as possibly help determine tumor ''aggressiveness''. However, the relative uptake in a prostate tumor can be so great that few other anatomical landmarks are visible in a PET image. Ultrasound imaging with a transrectal probe provides anatomical detail in the prostate region that can be co-registered with the sensitive functional information from the PET imaging. Imaging the prostate with both PET and transrectal ultrasound (TRUS) will help determine the location of any cancer within the prostate region. This dual-modality imaging should helpmore » provide better detection and treatment of prostate cancer. LBNL has built a high performance positron emission tomograph optimized to image the prostate.Compared to a standard whole-body PET camera, our prostate-optimized PET camera has the same sensitivity and resolution, less backgrounds and lower cost. We plan to develop the hardware and software tools needed for a validated dual PET/TRUS prostate imaging system. We also plan to develop dual prostate imaging with PET and external transabdominal ultrasound, in case the TRUS system is too uncomfortable for some patients. We present the design and intended clinical uses for these dual imaging systems.« less

A real-time MTFC algorithm of space remote-sensing camera based on FPGA

NASA Astrophysics Data System (ADS)

Zhao, Liting; Huang, Gang; Lin, Zhe

2018-01-01

A real-time MTFC algorithm of space remote-sensing camera based on FPGA was designed. The algorithm can provide real-time image processing to enhance image clarity when the remote-sensing camera running on-orbit. The image restoration algorithm adopted modular design. The MTF measurement calculation module on-orbit had the function of calculating the edge extension function, line extension function, ESF difference operation, normalization MTF and MTFC parameters. The MTFC image filtering and noise suppression had the function of filtering algorithm and effectively suppressing the noise. The algorithm used System Generator to design the image processing algorithms to simplify the design structure of system and the process redesign. The image gray gradient dot sharpness edge contrast and median-high frequency were enhanced. The image SNR after recovery reduced less than 1 dB compared to the original image. The image restoration system can be widely used in various fields.

Modular Scanning Confocal Microscope with Digital Image Processing

PubMed Central

McCluskey, Matthew D.

2016-01-01

In conventional confocal microscopy, a physical pinhole is placed at the image plane prior to the detector to limit the observation volume. In this work, we present a modular design of a scanning confocal microscope which uses a CCD camera to replace the physical pinhole for materials science applications. Experimental scans were performed on a microscope resolution target, a semiconductor chip carrier, and a piece of etched silicon wafer. The data collected by the CCD were processed to yield images of the specimen. By selecting effective pixels in the recorded CCD images, a virtual pinhole is created. By analyzing the image moments of the imaging data, a lateral resolution enhancement is achieved by using a 20 × / NA = 0.4 microscope objective at 532 nm laser wavelength. PMID:27829052

Pre-Clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices

DTIC Science & Technology

2007-11-01

accuracy. FPGA ADC data acquisition is controlled by distributed Java -based software. Java -based server application sits on each of the acquisition...JNI ( Java Native Interface) is used to allow Java indirect control of the USB driver. Fig. 5. Photograph of mobile electronics rack...supplies with the monitor and keyboard. The server application on each of these machines is controlled by a remote client Java -based application

Status of the NectarCAM camera project

NASA Astrophysics Data System (ADS)

Glicenstein, J.-F.; Barcelo, M.; Barrio, J.-A.; Blanch, O.; Boix, J.; Bolmont, J.; Boutonnet, C.; Brun, P.; Chabanne, E.; Champion, C.; Colonges, S.; Corona, P.; Courty, B.; Delagnes, E.; Delgado, C.; Diaz, C.; Ernenwein, J.-P.; Fegan, S.; Ferreira, O.; Fesquet, M.; Fontaine, G.; Fouque, N.; Henault, F.; Gascón, D.; Giebels, B.; Herranz, D.; Hermel, R.; Hoffmann, D.; Horan, D.; Houles, J.; Jean, P.; Karkar, S.; Knödlseder, J.; Martinez, G.; Lamanna, G.; LeFlour, T.; Lévêque, A.; Lopez-Coto, R.; Louis, F.; Moudden, Y.; Moulin, E.; Nayman, P.; Nunio, F.; Olive, J.-F.; Panazol, J.-L.; Pavy, S.; Petrucci, P.-O.; Punch, M.; Prast, Julie; Ramon, P.; Rateau, S.; Ribó, M.; Rosier-Lees, S.; Sanuy, A.; Sizun, P.; Sieiro, J.; Sulanke, K.-H.; Tavernet, J.-P.; Tejedor, L. A.; Toussenel, F.; Vasileiadis, G.; Voisin, V.; Waegebert, V.; Zurbach, C.

2014-07-01

NectarCAM is a camera designed for the medium-sized telescopes of the Cherenkov Telescope Array (CTA) covering the central energy range 100 GeV to 30 TeV. It has a modular design based on the NECTAr chip, at the heart of which is a GHz sampling Switched Capacitor Array and 12-bit Analog to Digital converter. The camera will be equipped with 265 7-photomultiplier modules, covering a field of view of 7 to 8 degrees. Each module includes the photomultiplier bases, High Voltage supply, pre-amplifier, trigger, readout and Thernet transceiver. Events recorded last between a few nanoseconds and tens of nanoseconds. A flexible trigger scheme allows to read out very long events. NectarCAM can sustain a data rate of 10 kHz. The camera concept, the design and tests of the various subcomponents and results of thermal and electrical prototypes are presented. The design includes the mechanical structure, the cooling of electronics, read-out, clock distribution, slow control, data-acquisition, trigger, monitoring and services. A 133-pixel prototype with full scale mechanics, cooling, data acquisition and slow control will be built at the end of 2014.

SPLASSH: Open source software for camera-based high-speed, multispectral in-vivo optical image acquisition

PubMed Central

Sun, Ryan; Bouchard, Matthew B.; Hillman, Elizabeth M. C.

2010-01-01

Camera-based in-vivo optical imaging can provide detailed images of living tissue that reveal structure, function, and disease. High-speed, high resolution imaging can reveal dynamic events such as changes in blood flow and responses to stimulation. Despite these benefits, commercially available scientific cameras rarely include software that is suitable for in-vivo imaging applications, making this highly versatile form of optical imaging challenging and time-consuming to implement. To address this issue, we have developed a novel, open-source software package to control high-speed, multispectral optical imaging systems. The software integrates a number of modular functions through a custom graphical user interface (GUI) and provides extensive control over a wide range of inexpensive IEEE 1394 Firewire cameras. Multispectral illumination can be incorporated through the use of off-the-shelf light emitting diodes which the software synchronizes to image acquisition via a programmed microcontroller, allowing arbitrary high-speed illumination sequences. The complete software suite is available for free download. Here we describe the software’s framework and provide details to guide users with development of this and similar software. PMID:21258475

Waterway wide area tactical coverage and homing (WaterWATCH) program overview

NASA Astrophysics Data System (ADS)

Driggers, Gerald; Cleveland, Tammy; Araujo, Lisa; Spohr, Robert; Umansky, Mark

2008-04-01

The Congressional and Army sponsored WaterWATCH TM Program has developed and demonstrated a fully integrated shallow water port and facility monitoring system. It provides fully automated monitoring of domains above and below the surface of the water using primarily off-the-shelf sensors and software. The system is modular, open architecture and IP based, and elements can be mixed and matched to adapt to specific applications. The sensors integrated into the WaterWATCH TM system include cameras, radar, passive and active sonar, and various motion detectors. The sensors were chosen based on extensive requirements analyses and tradeoffs. Descriptions of the system and individual sensors are provided, along with data from modular and system level testing. Camera test results address capabilities and limitations associated with using "smart" image analysis software with stressing environmental issues such as bugs, darkness, rain and snow. Radar issues addressed include achieving range and resolution requirements. The passive sonar capability to provide near 100% true positives with zero false positives is demonstrated. Testing results are also presented to show that inexpensive active sonar can be effective against divers with or without SCUBA gear and that false alarms due to fish can be minimized. A simple operator interface has also been demonstrated.

Pharmacologic intervention as an alternative to exercise stress

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gould, K.L.

1987-04-01

Although thallium exercise imaging has served an important role in clinical cardiology, it is significantly limited by suboptimal sensitivity and specificity, particularly in asymptomatic man. The increasing recognition of silent myocardial ischemia, the significant prevalence of coronary artery disease in asymptomatic middle age men, and the frequent occurrence of myocardial infarction without preceding symptoms in 60% of cases emphasizes the need for a more definitive, noninvasive diagnostic test for the presence of coronary artery disease suitable for screening in asymptomatic or symptomatic patients. Intravenous dipyridamole combined with handgrip stress provides a potent stimulus for purposes of diagnostic perfusion imaging. Althoughmore » planar and single photon emission computed tomography (SPECT) imaging also have played an important role, these techniques are seriously hindered by their inability to quantitate radiotracer uptake or image modest differences in maximum relative flow caused by coronary artery stenosis. Accordingly, the combination of dipyridamole-handgrip stress with positron imaging of myocardial perfusion has become a powerful diagnostic tool suitable for routine clinical use. With the availability of generator-produced rubidium-82, dedicated clinically oriented positron cameras, the routine application of positron imaging to clinical cardiology has become feasible. 75 references.« less

Upgraded cameras for the HESS imaging atmospheric Cherenkov telescopes

NASA Astrophysics Data System (ADS)

Giavitto, Gianluca; Ashton, Terry; Balzer, Arnim; Berge, David; Brun, Francois; Chaminade, Thomas; Delagnes, Eric; Fontaine, Gérard; Füßling, Matthias; Giebels, Berrie; Glicenstein, Jean-François; Gräber, Tobias; Hinton, James; Jahnke, Albert; Klepser, Stefan; Kossatz, Marko; Kretzschmann, Axel; Lefranc, Valentin; Leich, Holger; Lüdecke, Hartmut; Lypova, Iryna; Manigot, Pascal; Marandon, Vincent; Moulin, Emmanuel; de Naurois, Mathieu; Nayman, Patrick; Penno, Marek; Ross, Duncan; Salek, David; Schade, Markus; Schwab, Thomas; Simoni, Rachel; Stegmann, Christian; Steppa, Constantin; Thornhill, Julian; Toussnel, François

2016-08-01

The High Energy Stereoscopic System (H.E.S.S.) is an array of five imaging atmospheric Cherenkov telescopes, sensitive to cosmic gamma rays of energies between 30 GeV and several tens of TeV. Four of them started operations in 2003 and their photomultiplier tube (PMT) cameras are currently undergoing a major upgrade, with the goals of improving the overall performance of the array and reducing the failure rate of the ageing systems. With the exception of the 960 PMTs, all components inside the camera have been replaced: these include the readout and trigger electronics, the power, ventilation and pneumatic systems and the control and data acquisition software. New designs and technical solutions have been introduced: the readout makes use of the NECTAr analog memory chip, which samples and stores the PMT signals and was developed for the Cherenkov Telescope Array (CTA). The control of all hardware subsystems is carried out by an FPGA coupled to an embedded ARM computer, a modular design which has proven to be very fast and reliable. The new camera software is based on modern C++ libraries such as Apache Thrift, ØMQ and Protocol buffers, offering very good performance, robustness, flexibility and ease of development. The first camera was upgraded in 2015, the other three cameras are foreseen to follow in fall 2016. We describe the design, the performance, the results of the tests and the lessons learned from the first upgraded H.E.S.S. camera.

Positron Emission Tomography of the Heart

DOE R&D Accomplishments Database

Schelbert, H. R.; Phelps, M. E.; Kuhl, D. E.

1979-01-01

Positron emission computed tomography (PCT) represents an important new tool for the noninvasive evaluation and, more importantly, quantification of myocardial performance. Most currently available techniques permit assessment of only one aspect of cardiac function, i.e., myocardial perfusion by gamma scintillation camera imaging with Thallium-201 or left ventricular function by echocardiography or radionuclide angiocardiography. With PCT it may become possible to study all three major segments of myocardial performance, i.e., regional blood flow, mechanical function and, most importantly, myocardial metabolism. Each of these segments can either be evaluated separately or in combination. This report briefly describes the principles and technological advantages of the imaging device, reviews currently available radioactive tracers and how they can be employed for the assessment of flow, function and metabolism; and, lastly, discusses possible applications of PCT for the study of cardiac physiology or its potential role in the diagnosis of cardiac disease.

A novel, cost-effective, multi-point Thomson scattering system on the Pegasus Toroidal Experiment (invited)

DOE PAGES

Schlossberg, David J.; Bodner, Grant M.; Bongard, Michael W.; ...

2016-09-16

Here, a novel, cost-effective, multi-point Thomson scattering system has been designed, implemented, and operated on the Pegasus Toroidal Experiment. Leveraging advances in Nd:YAG lasers, high-efficiency volume phase holographic transmission gratings, and increased quantum-efficiency Generation 3 image-intensified charge coupled device (ICCD) cameras, the system provides Thomson spectra at eight spatial locations for a single grating/camera pair. The on-board digitization of the ICCD camera enables easy modular expansion, evidenced by recent extension from 4 to 12 plasma/background spatial location pairs. Stray light is rejected using time-of-flight methods suited to gated ICCDs, and background light is blocked during detector readout by a fastmore » shutter. This –10 3 reduction in background light enables further expansion to up to 24 spatial locations. The implementation now provides single-shot T e(R) for n e > 5 × 10 18 m –3.« less

REVIEW OF DEVELOPMENTS IN SPACE REMOTE SENSING FOR MONITORING RESOURCES.

USGS Publications Warehouse

Watkins, Allen H.; Lauer, D.T.; Bailey, G.B.; Moore, D.G.; Rohde, W.G.

1984-01-01

Space remote sensing systems are compared for suitability in assessing and monitoring the Earth's renewable resources. Systems reviewed include the Landsat Thematic Mapper (TM), the National Oceanic and Atmospheric Administration (NOAA) Advanced Very High Resolution Radiometer (AVHRR), the French Systeme Probatoire d'Observation de la Terre (SPOT), the German Shuttle Pallet Satellite (SPAS) Modular Optoelectronic Multispectral Scanner (MOMS), the European Space Agency (ESA) Spacelab Metric Camera, the National Aeronautics and Space Administration (NASA) Large Format Camera (LFC) and Shuttle Imaging Radar (SIR-A and -B), the Russian Meteor satellite BIK-E and fragment experiments and MKF-6M and KATE-140 camera systems, the ESA Earth Resources Satellite (ERS-1), the Japanese Marine Observation Satellite (MOS-1) and Earth Resources Satellite (JERS-1), the Canadian Radarsat, the Indian Resources Satellite (IRS), and systems proposed or planned by China, Brazil, Indonesia, and others. Also reviewed are the concepts for a 6-channel Shuttle Imaging Spectroradiometer, a 128-channel Shuttle Imaging Spectrometer Experiment (SISEX), and the U. S. Mapsat.

ePix: a class of architectures for second generation LCLS cameras

DOE PAGES

Dragone, A.; Caragiulo, P.; Markovic, B.; ...

2014-03-31

ePix is a novel class of ASIC architectures, based on a common platform, optimized to build modular scalable detectors for LCLS. The platform architecture is composed of a random access analog matrix of pixel with global shutter, fast parallel column readout, and dedicated sigma-delta analog-to-digital converters per column. It also implements a dedicated control interface and all the required support electronics to perform configuration, calibration and readout of the matrix. Based on this platform a class of front-end ASICs and several camera modules, meeting different requirements, can be developed by designing specific pixel architectures. This approach reduces development time andmore » expands the possibility of integration of detector modules with different size, shape or functionality in the same camera. The ePix platform is currently under development together with the first two integrating pixel architectures: ePix100 dedicated to ultra low noise applications and ePix10k for high dynamic range applications.« less

Pre-clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices

DTIC Science & Technology

2009-10-01

Field-of-View, Mobile PET/SPECT System for Bedside Environments: A Dynamic Cardiac Phantom Study using 99mTc and 18F- FDG . Presented at the American...using Tc-99m tracers and viability imaging using F- 18 tracers [3]-[7]. For cardiac F-18 imaging in a bedside environment, the 511 keV SPECT approach...SPECT system may have difficulty imaging subtle myocardial defects with F-18 tracers , but it may effectively image moderate to severe defects. The

Pre-clinical and Clinical Evaluation of High Resolution, Mobile Gamma Camera and Positron Imaging Devices

DTIC Science & Technology

2010-10-01

Downloaded on February 20,2010 at 10:55:59 EST from IEEE Xplore . Restrictions apply. STUDENSKI et al.: ACQUISITION AND PROCESSING METHODS FOR A BEDSIDE...February 20,2010 at 10:55:59 EST from IEEE Xplore . Restrictions apply. 208 IEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 57, NO. 1, FEBRUARY 2010 from the...59 EST from IEEE Xplore . Restrictions apply. STUDENSKI et al.: ACQUISITION AND PROCESSING METHODS FOR A BEDSIDE CARDIAC SPECT IMAGING SYSTEM 209

Nuclear medicine imaging system

DOEpatents

Bennett, G.W.; Brill, A.B.; Bizais, Y.J.C.; Rowe, R.W.; Zubal, I.G.

1983-03-11

It is an object of this invention to provide a nuclear imaging system having the versatility to do positron annihilation studies, rotating single or opposed camera gamma emission studies, and orthogonal gamma emission studies. It is a further object of this invention to provide an imaging system having the capability for orthogonal dual multipinhole tomography. It is another object of this invention to provide a nuclear imaging system in which all available energy data, as well as patient physiological data, are acquired simultaneously in list mode.

Configuration of electro-optic fire source detection system

NASA Astrophysics Data System (ADS)

Fabian, Ram Z.; Steiner, Zeev; Hofman, Nir

2007-04-01

The recent fighting activities in various parts of the world have highlighted the need for accurate fire source detection on one hand and fast "sensor to shooter cycle" capabilities on the other. Both needs can be met by the SPOTLITE system which dramatically enhances the capability to rapidly engage hostile fire source with a minimum of casualties to friendly force and to innocent bystanders. Modular system design enable to meet each customer specific requirements and enable excellent future growth and upgrade potential. The design and built of a fire source detection system is governed by sets of requirements issued by the operators. This can be translated into the following design criteria: I) Long range, fast and accurate fire source detection capability. II) Different threat detection and classification capability. III) Threat investigation capability. IV) Fire source data distribution capability (Location, direction, video image, voice). V) Men portability. ) In order to meet these design criteria, an optimized concept was presented and exercised for the SPOTLITE system. Three major modular components were defined: I) Electro Optical Unit -Including FLIR camera, CCD camera, Laser Range Finder and Marker II) Electronic Unit -including system computer and electronic. III) Controller Station Unit - Including the HMI of the system. This article discusses the system's components definition and optimization processes, and also show how SPOTLITE designers successfully managed to introduce excellent solutions for other system parameters.

Flat-panel video resolution LED display system

NASA Astrophysics Data System (ADS)

Wareberg, P. G.; Kennedy, D. I.

The system consists of a 128 x 128 element X-Y addressable LED array fabricated from green-emitting gallium phosphide. The LED array is interfaced with a 128 x 128 matrix TV camera. Associated electronics provides for seven levels of grey scale above zero with a grey scale ratio of square root of 2. Picture elements are on 0.008 inch centers resulting in a resolution of 125 lines-per-inch and a display area of approximately 1 sq. in. The LED array concept lends itself to modular construction, permitting assembly of a flat panel screen of any desired size from 1 x 1 inch building blocks without loss of resolution. A wide range of prospective aerospace applications exist extending from helmet-mounted systems involving small dedicated arrays to multimode cockpit displays constructed as modular screens. High-resolution LED arrays are already used as CRT replacements in military film-marking reconnaissance applications.

LST and instrument considerations. [modular design

NASA Technical Reports Server (NTRS)

Levin, G. M.

1974-01-01

In order that the LST meet its scientific objectives and also be a National Astronomical Space Facility during the 1980's and 1990's, broad requirements have been levied by the scientific community. These scientific requirements can be directly translated into design requirements and specifications for the scientific instruments. The instrument ensemble design must be consistent with a 15-year operational lifetime. Downtime for major repair/refurbishment or instrument updating must be minimized. The overall efficiency and performance of the instruments should be maximized. Modularization of instruments and instrument subsystems, some degree of on-orbit servicing (both repair and replacement), on-axis location, minimizing the number of reflections within instruments, minimizing polarization effects, and simultaneous operation of the F/24 camera with other instruments, are just a few of the design guidelines and specifications which can and will be met in order that these broader scientific requirements be satisfied.-

Direct Imaging of Radionuclide-Produced Electrons and Positrons with an Ultrathin Phosphor

PubMed Central

Chen, Liying; Gobar, Lisa S.; Knowles, Negar G.; Liu, Zhonglin; Gmitro, Arthur F.; Barrett, Harrison H.

2008-01-01

Current electron detectors are either unable to image in vivo or lack sufficient spatial resolution because of electron scattering in thick detector materials. This study was aimed at developing a sensitive high-resolution system capable of detecting electron-emitting isotopes in vivo. Methods The system uses a lens-coupled charge-coupled-device camera to capture the scintillation light excited by an electron-emitting object near an ultrathin phosphor. The spatial resolution and sensitivity of the system were measured with a 3.7-kBq 90Y/90Sr β-source and a 70-µm resin bead labeled with 99mTc. Finally, we imaged the 99mTc-pertechnetate concentration in the mandibular gland of a mouse in vivo. Results Useful images were obtained with only a few hundred emitted β particles from the 90Y/90Sr source or conversion electrons from the 99mTc bead source. The in vivo image showed a clear profile of the mandibular gland and many fine details with exposures of as low as 30 s. All measurements were consistent with a spatial resolution of about 50 µm, corresponding to 2.5 detector pixels with the current camera. Conclusion Our new electron-imaging system can image electron-emitting isotope distributions at high resolution and sensitivity. The system is useful for in vivo imaging of small animals and small, exposed regions on humans. The ability to image β particles, positrons, and conversion electrons makes the system applicable to most isotopes. PMID:18552136

Development of the geoCamera, a System for Mapping Ice from a Ship

NASA Astrophysics Data System (ADS)

Arsenault, R.; Clemente-Colon, P.

2012-12-01

The geoCamera produces maps of the ice surrounding an ice-capable ship by combining images from one or more digital cameras with the ship's position and attitude data. Maps are produced along the ship's path with the achievable width and resolution depending on camera mounting height as well as camera resolution and lens parameters. Our system has produced maps up to 2000m wide at 1m resolution. Once installed and calibrated, the system is designed to operate automatically producing maps in near real-time and making them available to on-board users via existing information systems. The resulting small-scale maps complement existing satellite based products as well as on-board observations. Development versions have temporarily been deployed in Antarctica on the RV Nathaniel B. Palmer in 2010 and in the Arctic on the USCGC Healy in 2011. A permanent system has been deployed during the summer of 2012 on the USCGC Healy. To make the system attractive to other ships of opportunity, design goals include using existing ship systems when practical, using low costs commercial-off-the-shelf components if additional hardware is necessary, automating the process to virtually eliminate adding to the workload of ships technicians and making the software components modular and flexible enough to allow more seamless integration with a ships particular IT system.

NH11B-1726: FrankenRaven: A New Platform for Remote Sensing

NASA Technical Reports Server (NTRS)

Dahlgren, Robert; Fladeland, Matthew M.; Pinsker, Ethan A.; Jasionowicz, John P.; Jones, Lowell L.; Pscheid, Matthew J.

2016-01-01

Small, modular aircraft are an emerging technology with a goal to maximize flexibility and enable multi-mission support. This reports the progress of an unmanned aerial system (UAS) project conducted at the NASA Ames Research Center (ARC) in 2016. This interdisciplinary effort builds upon the success of the 2014 FrankenEye project to apply rapid prototyping techniques to UAS, to develop a variety of platforms to host remote sensing instruments. In 2016, ARC received AeroVironment RQ-11A and RQ-11B Raven UAS from the US Department of the Interior, Office of Aviation Services. These aircraft have electric propulsion, a wingspan of roughly 1.3m, and have demonstrated reliability in challenging environments. The Raven airframe is an ideal foundation to construct more complex aircraft, and student interns using 3D printing were able to graft multiple Raven wings and fuselages into FrankenRaven aircraft. Aeronautical analysis shows that the new configuration has enhanced flight time, payload capacity, and distance compared to the original Raven. The FrankenRaven avionics architecture replaces the mil-spec avionics with COTS technology based upon the 3DR Pixhawk PX4 autopilot with a safety multiplexer for failsafe handoff to 2.4 GHz RC control and 915 MHz telemetry. This project demonstrates how design reuse, rapid prototyping, and modular subcomponents can be leveraged into flexible airborne platforms that can host a variety of remote sensing payloads and even multiple payloads. Modularity advances a new paradigm: mass-customization of aircraft around given payload(s). Multi-fuselage designs are currently under development to host a wide variety of payloads including a zenith-pointing spectrometer, a magnetometer, a multi-spectral camera, and a RGB camera. After airworthiness certification, flight readiness review, and test flights are performed at Crows Landing airfield in central California, field data will be taken at Kilauea volcano in Hawaii and other locations.

FrankenRaven: A New Platform for Remote Sensing

NASA Astrophysics Data System (ADS)

Dahlgren, R. P.; Fladeland, M. M.; Pinsker, E. A.; Jasionowicz, J. P.; Jones, L. L.; Mosser, C. D.; Pscheid, M. J.; Weidow, N. L.; Kelly, P. J.; Kern, C.; Werner, C. A.; Johnson, M. S.

2016-12-01

Small, modular aircraft are an emerging technology with a goal to maximize flexibility and enable multi-mission support. This reports the progress of an unmanned aerial system (UAS) project conducted at the NASA Ames Research Center (ARC) in 2016. This interdisciplinary effort builds upon the success of the 2014 FrankenEye project to apply rapid prototyping techniques to UAS, to develop a variety of platforms to host remote sensing instruments. In 2016, ARC received AeroVironment RQ-11A and RQ-11B Raven UAS from the US Department of the Interior, Office of Aviation Services. These aircraft have electric propulsion, a wingspan of roughly 1.3m, and have demonstrated reliability in challenging environments. The Raven airframe is an ideal foundation to construct more complex aircraft, and student interns using 3D printing were able to graft multiple Raven wings and fuselages into "FrankenRaven" aircraft. Aeronautical analysis shows that the new configuration has enhanced flight time, payload capacity, and distance compared to the original Raven. The FrankenRaven avionics architecture replaces the mil-spec avionics with COTS technology based upon the 3DR Pixhawk PX4 autopilot with a safety multiplexer for failsafe handoff to 2.4 GHz RC control and 915 MHz telemetry. This project demonstrates how design reuse, rapid prototyping, and modular subcomponents can be leveraged into flexible airborne platforms that can host a variety of remote sensing payloads and even multiple payloads. Modularity advances a new paradigm: mass-customization of aircraft around given payload(s). Multi-fuselage designs are currently under development to host a wide variety of payloads including a zenith-pointing spectrometer, a magnetometer, a multi-spectral camera, and a RGB camera. After airworthiness certification, flight readiness review, and test flights are performed at Crows Landing airfield in central California, field data will be taken at Kilauea volcano in Hawaii and other locations.

Artist's concept of Apollo 14 crewmen on their firs traverse of lunar surface

NASA Image and Video Library

1971-01-11

S71-16101 (January 1971) --- A Grumman Aerospace Corporation artist's concept of Apollo 14 crewmen, astronauts Alan B. Shepard Jr., commander, and Edgar D. Mitchell, lunar module pilot, as they set out on their first traverse. Shepard is pulling the Modularized Equipment Transporter (MET) which contains cameras, lunar sample bags, tools and other paraphernalia. Shepard has the Laser Ranging Retro-Reflector (LR-3) in his other hand. Mitchell is carrying the Apollo Lunar Surface Experiments Package (ALSEP) barbell mode.

Astronaut John Young at LRV prior to deployment of ALSEP during first EVA

NASA Technical Reports Server (NTRS)

1972-01-01

Astronaut John W. Young, commander of Apollo 16, is at the Lunar Roving Vehicle (LRV), just prior to deployment of the Apollo Lunar Surface Experiment Package (ALSEP) during the first extravehicular activity (EVA-1), on April 21, 1972. Note Ultraviolet Camera/Spectrometer at right of Lunar Module (LM) ladder. Also note pile of protective/thermal foil under the U.S. flag on the LM which the astronauts pulled away to get to the Modular Equipment Stowage Assembly (MESA) bay.

Sensor network based vehicle classification and license plate identification system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frigo, Janette Rose; Brennan, Sean M; Rosten, Edward J

Typically, for energy efficiency and scalability purposes, sensor networks have been used in the context of environmental and traffic monitoring applications in which operations at the sensor level are not computationally intensive. But increasingly, sensor network applications require data and compute intensive sensors such video cameras and microphones. In this paper, we describe the design and implementation of two such systems: a vehicle classifier based on acoustic signals and a license plate identification system using a camera. The systems are implemented in an energy-efficient manner to the extent possible using commercially available hardware, the Mica motes and the Stargate platform.more » Our experience in designing these systems leads us to consider an alternate more flexible, modular, low-power mote architecture that uses a combination of FPGAs, specialized embedded processing units and sensor data acquisition systems.« less

Real-time automatic inspection under adverse conditions

NASA Astrophysics Data System (ADS)

Carvalho, Fernando D.; Correia, Fernando C.; Freitas, Jose C. A.; Rodrigues, Fernando C.

1991-03-01

This paper presents the results of a R&D Program supported by a grant from the Ministry of Defense, devoted to the development of an inteffigent camera for surveillance in the open air. The effects of shadows, clouds and winds were problems to be solved without generating false alarm events. The system is based on a video CCD camera which generates a video CCIR signal. The signal is then processed in modular hardware which detects the changes in the scene and processes the image, in order to enhance the intruder image and path. Windows may be defined over the image in order to increase the information obtained about the intruder and a first approach to the classification of the type of intruder may be achieved. The paper describes the hardware used in the system, as well as the software, used for the installation of the camera and the software developed for the microprocessor which is responsible for the generation of the alarm signals. The paper also presents some results of surveillance tasks in the open air executed by the system with real time performance.

Quality controls for gamma cameras and PET cameras: development of a free open-source ImageJ program

NASA Astrophysics Data System (ADS)

Carlier, Thomas; Ferrer, Ludovic; Berruchon, Jean B.; Cuissard, Regis; Martineau, Adeline; Loonis, Pierre; Couturier, Olivier

2005-04-01

Acquisition data and treatments for quality controls of gamma cameras and Positron Emission Tomography (PET) cameras are commonly performed with dedicated program packages, which are running only on manufactured computers and differ from each other, depending on camera company and program versions. The aim of this work was to develop a free open-source program (written in JAVA language) to analyze data for quality control of gamma cameras and PET cameras. The program is based on the free application software ImageJ and can be easily loaded on any computer operating system (OS) and thus on any type of computer in every nuclear medicine department. Based on standard parameters of quality control, this program includes 1) for gamma camera: a rotation center control (extracted from the American Association of Physics in Medicine, AAPM, norms) and two uniformity controls (extracted from the Institute of Physics and Engineering in Medicine, IPEM, and National Electronic Manufacturers Association, NEMA, norms). 2) For PET systems, three quality controls recently defined by the French Medical Physicist Society (SFPM), i.e. spatial resolution and uniformity in a reconstructed slice and scatter fraction, are included. The determination of spatial resolution (thanks to the Point Spread Function, PSF, acquisition) allows to compute the Modulation Transfer Function (MTF) in both modalities of cameras. All the control functions are included in a tool box which is a free ImageJ plugin and could be soon downloaded from Internet. Besides, this program offers the possibility to save on HTML format the uniformity quality control results and a warning can be set to automatically inform users in case of abnormal results. The architecture of the program allows users to easily add any other specific quality control program. Finally, this toolkit is an easy and robust tool to perform quality control on gamma cameras and PET cameras based on standard computation parameters, is free, run on any type of computer and will soon be downloadable from the net (http://rsb.info.nih.gov/ij/plugins or http://nucleartoolkit.free.fr).

A preliminary evaluation of a dual crystal positron camera

NASA Astrophysics Data System (ADS)

Holte, S.; Ostertag, H.; Kesselberg, M.

1987-03-01

A dual crystal whole body camera based on Bi4Ge3O12 and Gd2SiO5 was built. Spatial transaxial resolution is better than 5 mm FWH1, with maintained high sensitivity. The system can be equipped with up to four rings to give sufficient coverage of the organs under study. It can perform true dynamic function studies with frame rates of the order of 1 sec or less and can handle high data acquisition rates, encountered in cerebral blood flow studies and in perfusion studies of the heart, with low dead time losses. High sampling redundancy is achieved by wobbling over two detector channels. Fast image reconstructions is achieved by an array processor. Tilting and rotating capabilities of the gantry facilitate the anatomical alignment of the image plane. A rotating line source is used for accurate transmission images with a low scatter level.

Myocardial perfusion imaging: Lessons learned and work to be done-update.

PubMed

Iskandrian, Ami E; Dilsizian, Vasken; Garcia, Ernest V; Beanlands, Rob S; Cerqueira, Manuel; Soman, Prem; Berman, Daniel S; Cuocolo, Alberto; Einstein, Andrew J; Morgan, Charity J; Hage, Fadi G; Schelbert, Heinrich R; Bax, Jeroen J; Wu, Joseph C; Shaw, Leslee J; Sadeghi, Mehran M; Tamaki, Nagara; Kaufmann, Philipp A; Gropler, Robert; Dorbala, Sharmila; Van Decker, William

2018-02-01

As the second term of our commitment to Journal begins, we, the editors, would like to reflect on a few topics that have relevance today. These include prognostication and paradigm shifts; Serial testing: How to handle data? Is the change in perfusion predictive of outcome and which one? Ischemia-guided therapy: fractional flow reserve vs perfusion vs myocardial blood flow; positron emission tomography (PET) imaging using Rubidium-82 vs N-13 ammonia vs F-18 Flurpiridaz; How to differentiate microvascular disease from 3-vessel disease by PET? The imaging scene outside the United States, what are the differences and similarities? Radiation exposure; Special issues with the new cameras? Is attenuation correction needed? Are there normal databases and are these specific to each camera system? And finally, hybrid imaging with single-photon emission tomography or PET combined with computed tomography angiography or coronary calcium score. We hope these topics are of interest to our readers.

Molecular Imaging in the College of Optical Sciences – An Overview of Two Decades of Instrumentation Development

PubMed Central

Furenlid, Lars R.; Barrett, Harrison H.; Barber, H. Bradford; Clarkson, Eric W.; Kupinski, Matthew A.; Liu, Zhonglin; Stevenson, Gail D.; Woolfenden, James M.

2015-01-01

During the past two decades, researchers at the University of Arizona’s Center for Gamma-Ray Imaging (CGRI) have explored a variety of approaches to gamma-ray detection, including scintillation cameras, solid-state detectors, and hybrids such as the intensified Quantum Imaging Device (iQID) configuration where a scintillator is followed by optical gain and a fast CCD or CMOS camera. We have combined these detectors with a variety of collimation schemes, including single and multiple pinholes, parallel-hole collimators, synthetic apertures, and anamorphic crossed slits, to build a large number of preclinical molecular-imaging systems that perform Single-Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), and X-Ray Computed Tomography (CT). In this paper, we discuss the themes and methods we have developed over the years to record and fully use the information content carried by every detected gamma-ray photon. PMID:26236069

Development of a novel handheld intra-operative laparoscopic Compton camera for 18F-Fluoro-2-deoxy-2-D-glucose-guided surgery

NASA Astrophysics Data System (ADS)

Nakamura, Y.; Shimazoe, K.; Takahashi, H.; Yoshimura, S.; Seto, Y.; Kato, S.; Takahashi, M.; Momose, T.

2016-08-01

As well as pre-operative roadmapping by 18F-Fluoro-2-deoxy-2-D-glucose (FDG) positron emission tomography, intra-operative localization of the tracer is important to identify local margins for less-invasive surgery, especially FDG-guided surgery. The objective of this paper is to develop a laparoscopic Compton camera and system aimed at use for intra-operative FDG imaging for accurate and less-invasive dissections. The laparoscopic Compton camera consists of four layers of a 12-pixel cross-shaped array of GFAG crystals (2× 2× 3 mm3) and through silicon via multi-pixel photon counters and dedicated individual readout electronics based on a dynamic time-over-threshold method. Experimental results yielded a spatial resolution of 4 mm (FWHM) for a 10 mm working distance and an absolute detection efficiency of 0.11 cps kBq-1, corresponding to an intrinsic detection efficiency of  ˜0.18%. In an experiment using a NEMA-like well-shaped FDG phantom, a φ 5× 10 mm cylindrical hot spot was clearly obtained even in the presence of a background distribution surrounding the Compton camera and the hot spot. We successfully obtained reconstructed images of a resected lymph node and primary tumor ex vivo after FDG administration to a patient having esophageal cancer. These performance characteristics indicate a new possibility of FDG-directed surgery by using a Compton camera intra-operatively.

THE ANGULAR DISTRIBUTION OF POSITRONS IN $pi$$sup +$-$mu$$sup +$-e$sup +$ DECAY IN PROPANE (in Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alikhanyan, A.I.; Kirillov-Ugryumov, V.G.; Kotenko, L.P.

1958-01-01

In consideration of the wide use of propane bubble cameras, investigations were made of the angular distribution of electrons from pi /sup +/ -- mu /sup +/--e/sup +/ decay in propane to determine the possibility of using propane in angular correlation measurements of processes simlar to mu --e decay. The scheme of the experiment made with a bubble chamber of (7.2 x 6.5 x 16)cm/ dmensions bombarded by a 175-Mev pi -meson beam from a phasotron is described. (R.V.J.)

CdTe Based Hard X-ray Imager Technology For Space Borne Missions

NASA Astrophysics Data System (ADS)

Limousin, Olivier; Delagnes, E.; Laurent, P.; Lugiez, F.; Gevin, O.; Meuris, A.

2009-01-01

CEA Saclay has recently developed an innovative technology for CdTe based Pixelated Hard X-Ray Imagers with high spectral performance and high timing resolution for efficient background rejection when the camera is coupled to an active veto shield. This development has been done in a R&D program supported by CNES (French National Space Agency) and has been optimized towards the Simbol-X mission requirements. In the latter telescope, the hard X-Ray imager is 64 cm² and is equipped with 625µm pitch pixels (16384 independent channels) operating at -40°C in the range of 4 to 80 keV. The camera we demonstrate in this paper consists of a mosaic of 64 independent cameras, divided in 8 independent sectors. Each elementary detection unit, called Caliste, is the hybridization of a 256-pixel Cadmium Telluride (CdTe) detector with full custom front-end electronics into a unique 1 cm² component, juxtaposable on its four sides. Recently, promising results have been obtained from the first micro-camera prototypes called Caliste 64 and will be presented to illustrate the capabilities of the device as well as the expected performance of an instrument based on it. The modular design of Caliste enables to consider extended developments toward IXO type mission, according to its specific scientific requirements.

Cheap streak camera based on the LD-S-10 intensifier tube

NASA Astrophysics Data System (ADS)

Dashevsky, Boris E.; Krutik, Mikhail I.; Surovegin, Alexander L.

1992-01-01

Basic properties of a new streak camera and its test results are reported. To intensify images on its screen, we employed modular G1 tubes, the LD-A-1.0 and LD-A-0.33, enabling magnification of 1.0 and 0.33, respectively. If necessary, the LD-A-0.33 tube may be substituted by any other image intensifier of the LDA series, the choice to be determined by the size of the CCD matrix with fiber-optical windows. The reported camera employs a 12.5- mm-long CCD strip consisting of 1024 pixels, each 12 X 500 micrometers in size. Registered radiation was imaged on a 5 X 0.04 mm slit diaphragm tightly connected with the LD-S- 10 fiber-optical input window. Electrons escaping the cathode are accelerated in a 5 kV electric field and focused onto a phosphor screen covering a fiber-optical plate as they travel between deflection plates. Sensitivity of the latter was 18 V/mm, which implies that the total deflecting voltage was 720 V per 40 mm of the screen surface, since reversed-polarity scan pulses +360 V and -360 V were applied across the deflection plate. The streak camera provides full scan times over the screen of 15, 30, 50, 100, 250, and 500 ns. Timing of the electrically or optically driven camera was done using a 10 ns step-controlled-delay (0 - 500 ns) circuit.

Thermal regulation for APDs in a 1 mm(3) resolution clinical PET camera: design, simulation and experimental verification.

PubMed

Zhai, Jinjian; Vandenbroucke, Arne; Levin, Craig S

2014-07-21

We are developing a 1 mm(3) resolution positron emission tomography camera dedicated to breast imaging. The camera collects high energy photons emitted from radioactively labeled agents introduced in the patients in order to detect molecular signatures of breast cancer. The camera comprises many layers of lutetium yttrium oxyorthosilicate (LYSO) scintillation crystals coupled to position sensitive avalanche photodiodes (PSAPDs). The main objectives of the studies presented in this paper are to investigate the temperature profile of the layers of LYSO-PSAPD detectors (a.k.a. 'fins') residing in the camera and to use these results to present the design of the thermal regulation system for the front end of the camera. The study was performed using both experimental methods and simulation. We investigated a design with a heat-dissipating fin. Three fin configurations are tested: fin with Al windows (FwW), fin without Al windows (FwoW) and fin with alumina windows (FwAW). A Fluent® simulation was conducted to study the experimentally inaccessible temperature of the PSAPDs. For the best configuration (FwW), the temperature difference from the center to a point near the edge is 1.0 K when 1.5 A current was applied to the Peltier elements. Those of FwoW and FwAW are 2.6 K and 1.7 K, respectively. We conclude that the design of a heat-dissipating fin configuration with 'aluminum windows' (FwW) that borders the scintillation crystal arrays of 16 adjacent detector modules has better heat dissipation capabilities than the design without 'aluminum windows' (FwoW) and the design with 'alumina windows' (FwAW), respectively.

Optimization and verification of image reconstruction for a Compton camera towards application as an on-line monitor for particle therapy

NASA Astrophysics Data System (ADS)

Taya, T.; Kataoka, J.; Kishimoto, A.; Tagawa, L.; Mochizuki, S.; Toshito, T.; Kimura, M.; Nagao, Y.; Kurita, K.; Yamaguchi, M.; Kawachi, N.

2017-07-01

Particle therapy is an advanced cancer therapy that uses a feature known as the Bragg peak, in which particle beams suddenly lose their energy near the end of their range. The Bragg peak enables particle beams to damage tumors effectively. To achieve precise therapy, the demand for accurate and quantitative imaging of the beam irradiation region or dosage during therapy has increased. The most common method of particle range verification is imaging of annihilation gamma rays by positron emission tomography. Not only 511-keV gamma rays but also prompt gamma rays are generated during therapy; therefore, the Compton camera is expected to be used as an on-line monitor for particle therapy, as it can image these gamma rays in real time. Proton therapy, one of the most common particle therapies, uses a proton beam of approximately 200 MeV, which has a range of ~ 25 cm in water. As gamma rays are emitted along the path of the proton beam, quantitative evaluation of the reconstructed images of diffuse sources becomes crucial, but it is far from being fully developed for Compton camera imaging at present. In this study, we first quantitatively evaluated reconstructed Compton camera images of uniformly distributed diffuse sources, and then confirmed that our Compton camera obtained 3 %(1 σ) and 5 %(1 σ) uniformity for line and plane sources, respectively. Based on this quantitative study, we demonstrated on-line gamma imaging during proton irradiation. Through these studies, we show that the Compton camera is suitable for future use as an on-line monitor for particle therapy.

Coronagraph for astronomical imaging and spectrophotometry

NASA Technical Reports Server (NTRS)

Vilas, Faith; Smith, Bradford A.

1987-01-01

A coronagraph designed to minimize scattered light in astronomical observations caused by the structure of the primary mirror, secondary mirror, and secondary support structure of a Cassegrainian telescope is described. Direct (1:1) and reducing (2.7:1) imaging of astronomical fields are possible. High-quality images are produced. The coronagraph can be used with either a two-dimensional charge-coupled device or photographic film camera. The addition of transmission dispersing optics converts the coronagraph into a low-resolution spectrograph. The instrument is modular and portable for transport to different observatories.

Laboratory demonstration of image reconstruction for coherent optical system of modular imaging collectors (COSMIC)

NASA Technical Reports Server (NTRS)

Traub, W. A.

1984-01-01

The first physical demonstration of the principle of image reconstruction using a set of images from a diffraction-blurred elongated aperture is reported. This is an optical validation of previous theoretical and numerical simulations of the COSMIC telescope array (coherent optical system of modular imaging collectors). The present experiment utilizes 17 diffraction blurred exposures of a laboratory light source, as imaged by a lens covered by a narrow-slit aperture; the aperture is rotated 10 degrees between each exposure. The images are recorded in digitized form by a CCD camera, Fourier transformed, numerically filtered, and added; the sum is then filtered and inverse Fourier transformed to form the final image. The image reconstruction process is found to be stable with respect to uncertainties in values of all physical parameters such as effective wavelength, rotation angle, pointing jitter, and aperture shape. Future experiments will explore the effects of low counting rates, autoguiding on the image, various aperture configurations, and separated optics.

Intercampus network of the Department of Radiology, School of Medicine, Indiana University

NASA Astrophysics Data System (ADS)

Witt, Robert M.; Gibbs, Thomas; Holden, Robert W.

1994-05-01

During the past year, the Department of Radiology, School of Medicine, Indiana University designed, specified, and installed a campus wide network. The network supports three functions: a laser camera network to allow the transfer of hard copy images across the campus; a positron emission tomography (PET) network to allow the interconnection of the workstations comprising the PET system; and a future personal computer network to allow support of departmental administrative functions with an upgrade path to allow the display of soft copy images in physician offices and other locations in the department.

Multisensory System for Fruit Harvesting Robots. Experimental Testing in Natural Scenarios and with Different Kinds of Crops

PubMed Central

Fernández, Roemi; Salinas, Carlota; Montes, Héctor; Sarria, Javier

2014-01-01

The motivation of this research was to explore the feasibility of detecting and locating fruits from different kinds of crops in natural scenarios. To this end, a unique, modular and easily adaptable multisensory system and a set of associated pre-processing algorithms are proposed. The offered multisensory rig combines a high resolution colour camera and a multispectral system for the detection of fruits, as well as for the discrimination of the different elements of the plants, and a Time-Of-Flight (TOF) camera that provides fast acquisition of distances enabling the localisation of the targets in the coordinate space. A controlled lighting system completes the set-up, increasing its flexibility for being used in different working conditions. The pre-processing algorithms designed for the proposed multisensory system include a pixel-based classification algorithm that labels areas of interest that belong to fruits and a registration algorithm that combines the results of the aforementioned classification algorithm with the data provided by the TOF camera for the 3D reconstruction of the desired regions. Several experimental tests have been carried out in outdoors conditions in order to validate the capabilities of the proposed system. PMID:25615730

Quantitative analysis of a reconstruction method for fully three-dimensional PET.

PubMed

Suckling, J; Ott, R J; Deehan, B J

1992-03-01

The major advantage of positron emission tomography (PET) using large area planar detectors over scintillator-based commercial ring systems is the potentially larger (by a factor of two or three) axial field-of-view (FOV). However, to achieve the space invariance of the point spread function necessary for Fourier filtering a polar angle rejection criterion is applied to the data during backprojection resulting in a trade-off between FOV size and sensitivity. A new algorithm due to Defrise and co-workers developed for list-mode data overcomes this problem with a solution involving the division of the image into several subregions. A comparison between the existing backprojection-then-filter algorithm and the new method (with three subregions) has been made using both simulated and real data collected from the MUP-PET positron camera. Signal-to-noise analysis reveals that improvements of up to a factor of 1.4 are possible resulting from an increased data usage of up to a factor of 2.5 depending on the axial extent of the imaged object. Quantitation is also improved.

Nuclear Cardiology: Are We Using the Right Protocols and Tracers the Right Way?

PubMed

Dondi, Maurizio; Pascual, Thomas; Paez, Diana; Einstein, Andrew J

2017-12-01

The field of nuclear cardiology has changed considerably over recent years, with greater attention paid to safety and radiation protection issues. The wider usage of technetium-99m (Tc-99m)-labeled radiopharmaceuticals for single-photon emission computed tomography (SPECT) imaging using gamma cameras has contributed to better quality studies and lower radiation exposure to patients. Increased availability of tracers and scanners for positron emission tomography (PET) will help further improve the quality of studies and quantify myocardial blood flow and myocardial flow reserve, thus enhancing the contribution of non-invasive imaging to the management of coronary artery disease. The introduction of new instrumentation such as solid state cameras and new software will help reduce further radiation exposure to patients undergoing nuclear cardiology studies. Results from recent studies, focused on assessing the relationship between best practices and radiation risk, provide useful insights on simple measures to improve the safety of nuclear cardiology studies without compromising the quality of results.

Imaging Total Stations - Modular and Integrated Concepts

NASA Astrophysics Data System (ADS)

Hauth, Stefan; Schlüter, Martin

2010-05-01

Keywords: 3D-Metrology, Engineering Geodesy, Digital Image Processing Initialized in 2009, the Institute for Spatial Information and Surveying Technology i3mainz, Mainz University of Applied Sciences, forces research towards modular concepts for imaging total stations. On the one hand, this research is driven by the successful setup of high precision imaging motor theodolites in the near past, on the other hand it is pushed by the actual introduction of integrated imaging total stations to the positioning market by the manufacturers Topcon and Trimble. Modular concepts for imaging total stations are manufacturer independent to a large extent and consist of a particular combination of accessory hardware, software and algorithmic procedures. The hardware part consists mainly of an interchangeable eyepiece adapter offering opportunities for digital imaging and motorized focus control. An easy assembly and disassembly in the field is possible allowing the user to switch between the classical and the imaging use of a robotic total station. The software part primarily has to ensure hardware control, but several level of algorithmic support might be added and have to be distinguished. Algorithmic procedures allow to reach several levels of calibration concerning the geometry of the external digital camera and the total station. We deliver insight in our recent developments and quality characteristics. Both the modular and the integrated approach seem to have its individual strengths and weaknesses. Therefore we expect that both approaches might point at different target applications. Our aim is a better understanding of appropriate applications for robotic imaging total stations. First results are presented. Stefan Hauth, Martin Schlüter i3mainz - Institut für Raumbezogene Informations- und Messtechnik FH Mainz University of Applied Sciences Lucy-Hillebrand-Straße 2, 55128 Mainz, Germany

[Results of the EGRET Detector Program

NASA Technical Reports Server (NTRS)

Carter-Lewis, D. A.

1998-01-01

This NASA grant has funded studies of cosmic objects observed by both the EGRET detector aboard the Compton Gamma-ray Observatory and Whipple Gamma-ray imaging telescope. The former has sensitivity up to a few GeV and latter has sensitivity starting at about 200 GeV extending up to beyond 10 TeV. Thus these instruments probe some of the most energetic phenomena in the universe. This program has been in place for several years and led to important results referred to below. The Whipple Observatory Imaging Cherenkov Telescope consists of a 10-meter reflector with a nanosecond photomultiplier-tube camera at the focal plane. During the time period covered by this grant, it had either 109 pixels or 151 pixels on a 1/4 degree hexagonal pattern. As a TeV gamma ray enters the atmosphere, it produces an electron/positron pair initiating an extensive air shower. Cherenkov light from the electrons and positrons in the shower form an image of the shower at the phototube camera. The shape and intensity of this image is used to distinguish gamma-ray initiated showers from cosmic-ray (largely proton and alpha-particle) background showers and to derive an energy estimate for the primary gamma-ray. The Whipple Observatory gamma-ray collaboration pioneered this imaging technique which normally rejects over 99 percent of the cosmic-ray background while keeping over 70 percent of the gamma-ray signal. One of its key features is 2 large collection area which can exceed 50,000 meters. This grant covered primarily correlated observations of Markarian 421 and observations of the Cygnus region. The former resulted in a multiwavelength campaign showing correlations in several wavebands. The TeV data showed dramatic variability with the emission characterized by day-scale flickering and with now well defined steady component.

Role for positron emission tomography in skeletal diseases.

PubMed

Duet, Michèle; Pouchot, Jacques; Lioté, Frédéric; Faraggi, Marc

2007-01-01

Imaging plays a prominent role in the diagnosis and management of rheumatic diseases. Conventional imaging methods provide high-resolution structural information but usually fail to distinguish between active lesions and residual changes. Positron emission tomography (PET) with the tracer 18F-fluorodeoxyglucose (18F-FDG) was recently introduced into clinical practice as a means of obtaining information on both structure and metabolic activity. 18F-FDG-PET is widely used in oncology and may be valuable in patients with infections or inflammatory diseases, most notably vasculitis. Although encouraging results have been published, the number of studies remains small, as 18F-FDG-PET is an expensive investigation that is not available everywhere. Further work is needed to determine the cost-effectiveness ratio of 18F-FDG-PET in patients with infections or inflammatory diseases. Imaging plays a prominent role in the diagnosis and management of many musculoskeletal diseases. Although considerable progress has been made recently, the structural information supplied by conventional imaging methods is inadequate in some patients. Positron emission tomography (PET) after injection of 18fluorodeoxyglucose (18F-FDG) provides information on tissue metabolism. The usefulness of 18F-FDG-PET in oncology is now widely recognized. Other uses are emerging, in part thanks to the development of new cameras that combine dedicated detectors and an X-scanner in order to ensure accurate three-dimensional localization of metabolically active lesions. However, the exact role for 18F-FDG-PET needs to be studied in larger populations of patients.

Estimation of Anthocyanin Content of Berries by NIR Method

NASA Astrophysics Data System (ADS)

Zsivanovits, G.; Ludneva, D.; Iliev, A.

2010-01-01

Anthocyanin contents of fruits were estimated by VIS spectrophotometer and compared with spectra measured by NIR spectrophotometer (600-1100 nm step 10 nm). The aim was to find a relationship between NIR method and traditional spectrophotometric method. The testing protocol, using NIR, is easier, faster and non-destructive. NIR spectra were prepared in pairs, reflectance and transmittance. A modular spectrocomputer, realized on the basis of a monochromator and peripherals Bentham Instruments Ltd (GB) and a photometric camera created at Canning Research Institute, were used. An important feature of this camera is the possibility offered for a simultaneous measurement of both transmittance and reflectance with geometry patterns T0/180 and R0/45. The collected spectra were analyzed by CAMO Unscrambler 9.1 software, with PCA, PLS, PCR methods. Based on the analyzed spectra quality and quantity sensitive calibrations were prepared. The results showed that the NIR method allows measuring of the total anthocyanin content in fresh berry fruits or processed products without destroying them.

Estimation of Anthocyanin Content of Berries by NIR Method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zsivanovits, G.; Ludneva, D.; Iliev, A.

2010-01-21

Anthocyanin contents of fruits were estimated by VIS spectrophotometer and compared with spectra measured by NIR spectrophotometer (600-1100 nm step 10 nm). The aim was to find a relationship between NIR method and traditional spectrophotometric method. The testing protocol, using NIR, is easier, faster and non-destructive. NIR spectra were prepared in pairs, reflectance and transmittance. A modular spectrocomputer, realized on the basis of a monochromator and peripherals Bentham Instruments Ltd (GB) and a photometric camera created at Canning Research Institute, were used. An important feature of this camera is the possibility offered for a simultaneous measurement of both transmittance andmore » reflectance with geometry patterns T0/180 and R0/45. The collected spectra were analyzed by CAMO Unscrambler 9.1 software, with PCA, PLS, PCR methods. Based on the analyzed spectra quality and quantity sensitive calibrations were prepared. The results showed that the NIR method allows measuring of the total anthocyanin content in fresh berry fruits or processed products without destroying them.« less

Collaborated measurement of three-dimensional position and orientation errors of assembled miniature devices with two vision systems

NASA Astrophysics Data System (ADS)

Wang, Xiaodong; Zhang, Wei; Luo, Yi; Yang, Weimin; Chen, Liang

2013-01-01

In assembly of miniature devices, the position and orientation of the parts to be assembled should be guaranteed during or after assembly. In some cases, the relative position or orientation errors among the parts can not be measured from only one direction using visual method, because of visual occlusion or for the features of parts located in a three-dimensional way. An automatic assembly system for precise miniature devices is introduced. In the modular assembly system, two machine vision systems were employed for measurement of the three-dimensionally distributed assembly errors. High resolution CCD cameras and high position repeatability precision stages were integrated to realize high precision measurement in large work space. The two cameras worked in collaboration in measurement procedure to eliminate the influence of movement errors of the rotational or translational stages. A set of templates were designed for calibration of the vision systems and evaluation of the system's measurement accuracy.

Visual tracking for multi-modality computer-assisted image guidance

NASA Astrophysics Data System (ADS)

Basafa, Ehsan; Foroughi, Pezhman; Hossbach, Martin; Bhanushali, Jasmine; Stolka, Philipp

2017-03-01

With optical cameras, many interventional navigation tasks previously relying on EM, optical, or mechanical guidance can be performed robustly, quickly, and conveniently. We developed a family of novel guidance systems based on wide-spectrum cameras and vision algorithms for real-time tracking of interventional instruments and multi-modality markers. These navigation systems support the localization of anatomical targets, support placement of imaging probe and instruments, and provide fusion imaging. The unique architecture - low-cost, miniature, in-hand stereo vision cameras fitted directly to imaging probes - allows for an intuitive workflow that fits a wide variety of specialties such as anesthesiology, interventional radiology, interventional oncology, emergency medicine, urology, and others, many of which see increasing pressure to utilize medical imaging and especially ultrasound, but have yet to develop the requisite skills for reliable success. We developed a modular system, consisting of hardware (the Optical Head containing the mini cameras) and software (components for visual instrument tracking with or without specialized visual features, fully automated marker segmentation from a variety of 3D imaging modalities, visual observation of meshes of widely separated markers, instant automatic registration, and target tracking and guidance on real-time multi-modality fusion views). From these components, we implemented a family of distinct clinical and pre-clinical systems (for combinations of ultrasound, CT, CBCT, and MRI), most of which have international regulatory clearance for clinical use. We present technical and clinical results on phantoms, ex- and in-vivo animals, and patients.

MIRIADS: miniature infrared imaging applications development system description and operation

NASA Astrophysics Data System (ADS)

Baxter, Christopher R.; Massie, Mark A.; McCarley, Paul L.; Couture, Michael E.

2001-10-01

A cooperative effort between the U.S. Air Force Research Laboratory, Nova Research, Inc., the Raytheon Infrared Operations (RIO) and Optics 1, Inc. has successfully produced a miniature infrared camera system that offers significant real-time signal and image processing capabilities by virtue of its modular design. This paper will present an operational overview of the system as well as results from initial testing of the 'Modular Infrared Imaging Applications Development System' (MIRIADS) configured as a missile early-warning detection system. The MIRIADS device can operate virtually any infrared focal plane array (FPA) that currently exists. Programmable on-board logic applies user-defined processing functions to the real-time digital image data for a variety of functions. Daughterboards may be plugged onto the system to expand the digital and analog processing capabilities of the system. A unique full hemispherical infrared fisheye optical system designed and produced by Optics 1, Inc. is utilized by the MIRIADS in a missile warning application to demonstrate the flexibility of the overall system to be applied to a variety of current and future AFRL missions.

Large scale micro-photometry for high resolution pH-characterization during electro-osmotic pumping and modular micro-swimming

NASA Astrophysics Data System (ADS)

Niu, Ran; Khodorov, Stanislav; Weber, Julian; Reinmüller, Alexander; Palberg, Thomas

2017-11-01

Micro-fluidic pumps as well as artificial micro-swimmers are conveniently realized exploiting phoretic solvent flows based on local gradients of temperature, electrolyte concentration or pH. We here present a facile micro-photometric method for monitoring pH gradients and demonstrate its performance and scope on different experimental situations including an electro-osmotic pump and modular micro-swimmers assembled from ion exchange resin beads and polystyrene colloids. In combination with the present microscope and DSLR camera our method offers a 2 μm spatial resolution at video frame rate over a field of view of 3920 × 2602 μm2. Under optimal conditions we achieve a pH-resolution of 0.05 with about equal contributions from statistical and systematical uncertainties. Our quantitative micro-photometric characterization of pH gradients which develop in time and reach out several mm is anticipated to provide valuable input for reliable modeling and simulations of a large variety of complex flow situations involving pH-gradients including artificial micro-swimmers, microfluidic pumping or even electro-convection.

Integrated multisensor perimeter detection systems

NASA Astrophysics Data System (ADS)

Kent, P. J.; Fretwell, P.; Barrett, D. J.; Faulkner, D. A.

2007-10-01

The report describes the results of a multi-year programme of research aimed at the development of an integrated multi-sensor perimeter detection system capable of being deployed at an operational site. The research was driven by end user requirements in protective security, particularly in threat detection and assessment, where effective capability was either not available or prohibitively expensive. Novel video analytics have been designed to provide robust detection of pedestrians in clutter while new radar detection and tracking algorithms provide wide area day/night surveillance. A modular integrated architecture based on commercially available components has been developed. A graphical user interface allows intuitive interaction and visualisation with the sensors. The fusion of video, radar and other sensor data provides the basis of a threat detection capability for real life conditions. The system was designed to be modular and extendable in order to accommodate future and legacy surveillance sensors. The current sensor mix includes stereoscopic video cameras, mmWave ground movement radar, CCTV and a commercially available perimeter detection cable. The paper outlines the development of the system and describes the lessons learnt after deployment in a pilot trial.

Signal intensity analysis and optimization for in vivo imaging of Cherenkov and excited luminescence

NASA Astrophysics Data System (ADS)

LaRochelle, Ethan P. M.; Shell, Jennifer R.; Gunn, Jason R.; Davis, Scott C.; Pogue, Brian W.

2018-04-01

During external beam radiotherapy (EBRT), in vivo Cherenkov optical emissions can be used as a dosimetry tool or to excite luminescence, termed Cherenkov-excited luminescence (CEL) with microsecond-level time-gated cameras. The goal of this work was to develop a complete theoretical foundation for the detectable signal strength, in order to provide guidance on optimization of the limits of detection and how to optimize near real time imaging. The key parameters affecting photon production, propagation and detection were considered and experimental validation with both tissue phantoms and a murine model are shown. Both the theoretical analysis and experimental data indicate that the detection level is near a single photon-per-pixel for the detection geometry and frame rates commonly used, with the strongest factor being the signal decrease with the square of distance from tissue to camera. Experimental data demonstrates how the SNR improves with increasing integration time, but only up to the point where the dominance of camera read noise is overcome by stray photon noise that cannot be suppressed. For the current camera in a fixed geometry, the signal to background ratio limits the detection of light signals, and the observed in vivo Cherenkov emission is on the order of 100×  stronger than CEL signals. As a result, imaging signals from depths  <15 mm is reasonable for Cherenkov light, and depths  <3 mm is reasonable for CEL imaging. The current investigation modeled Cherenkov and CEL imaging of two oxygen sensing phosphorescent compounds, but the modularity of the code allows for easy comparison of different agents or alternative cameras, geometries or tissues.

Signal intensity analysis and optimization for in vivo imaging of Cherenkov and excited luminescence.

PubMed

LaRochelle, Ethan P M; Shell, Jennifer R; Gunn, Jason R; Davis, Scott C; Pogue, Brian W

2018-04-20

During external beam radiotherapy (EBRT), in vivo Cherenkov optical emissions can be used as a dosimetry tool or to excite luminescence, termed Cherenkov-excited luminescence (CEL) with microsecond-level time-gated cameras. The goal of this work was to develop a complete theoretical foundation for the detectable signal strength, in order to provide guidance on optimization of the limits of detection and how to optimize near real time imaging. The key parameters affecting photon production, propagation and detection were considered and experimental validation with both tissue phantoms and a murine model are shown. Both the theoretical analysis and experimental data indicate that the detection level is near a single photon-per-pixel for the detection geometry and frame rates commonly used, with the strongest factor being the signal decrease with the square of distance from tissue to camera. Experimental data demonstrates how the SNR improves with increasing integration time, but only up to the point where the dominance of camera read noise is overcome by stray photon noise that cannot be suppressed. For the current camera in a fixed geometry, the signal to background ratio limits the detection of light signals, and the observed in vivo Cherenkov emission is on the order of 100×  stronger than CEL signals. As a result, imaging signals from depths  <15 mm is reasonable for Cherenkov light, and depths  <3 mm is reasonable for CEL imaging. The current investigation modeled Cherenkov and CEL imaging of two oxygen sensing phosphorescent compounds, but the modularity of the code allows for easy comparison of different agents or alternative cameras, geometries or tissues.

Polymorphic robotic system controlled by an observing camera

NASA Astrophysics Data System (ADS)

Koçer, Bilge; Yüksel, Tugçe; Yümer, M. Ersin; Özen, C. Alper; Yaman, Ulas

2010-02-01

Polymorphic robotic systems, which are composed of many modular robots that act in coordination to achieve a goal defined on the system level, have been drawing attention of industrial and research communities since they bring additional flexibility in many applications. This paper introduces a new polymorphic robotic system, in which the detection and control of the modules are attained by a stationary observing camera. The modules do not have any sensory equipment for positioning or detecting each other. They are self-powered, geared with means of wireless communication and locking mechanisms, and are marked to enable the image processing algorithm detect the position and orientation of each of them in a two dimensional space. Since the system does not depend on the modules for positioning and commanding others, in a circumstance where one or more of the modules malfunction, the system will be able to continue operating with the rest of the modules. Moreover, to enhance the compatibility and robustness of the system under different illumination conditions, stationary reference markers are employed together with global positioning markers, and an adaptive filtering parameter decision methodology is enclosed. To the best of authors' knowledge, this is the first study to introduce a remote camera observer to control modules of a polymorphic robotic system.

Automated recognition and tracking of aerosol threat plumes with an IR camera pod

NASA Astrophysics Data System (ADS)

Fauth, Ryan; Powell, Christopher; Gruber, Thomas; Clapp, Dan

2012-06-01

Protection of fixed sites from chemical, biological, or radiological aerosol plume attacks depends on early warning so that there is time to take mitigating actions. Early warning requires continuous, autonomous, and rapid coverage of large surrounding areas; however, this must be done at an affordable cost. Once a potential threat plume is detected though, a different type of sensor (e.g., a more expensive, slower sensor) may be cued for identification purposes, but the problem is to quickly identify all of the potential threats around the fixed site of interest. To address this problem of low cost, persistent, wide area surveillance, an IR camera pod and multi-image stitching and processing algorithms have been developed for automatic recognition and tracking of aerosol plumes. A rugged, modular, static pod design, which accommodates as many as four micro-bolometer IR cameras for 45deg to 180deg of azimuth coverage, is presented. Various OpenCV1 based image-processing algorithms, including stitching of multiple adjacent FOVs, recognition of aerosol plume objects, and the tracking of aerosol plumes, are presented using process block diagrams and sample field test results, including chemical and biological simulant plumes. Methods for dealing with the background removal, brightness equalization between images, and focus quality for optimal plume tracking are also discussed.

Evaluating the purity of a {sup 57}Co flood source by PET

DOE Office of Scientific and Technical Information (OSTI.GOV)

DiFilippo, Frank P., E-mail: difilif@ccf.org

2014-11-01

Purpose: Flood sources of {sup 57}Co are commonly used for quality control of gamma cameras. Flood uniformity may be affected by the contaminants {sup 56}Co and {sup 58}Co, which emit higher energy photons. Although vendors specify a maximum combined {sup 56}Co and {sup 58}Co activity, a convenient test for flood source purity that is feasible in a clinical environment would be desirable. Methods: Both {sup 56}Co and {sup 58}Co emit positrons with branching 19.6% and 14.9%, respectively. As is known from {sup 90}Y imaging, a positron emission tomography (PET) scanner is capable of quantitatively imaging very weak positron emission inmore » a high single-photon background. To evaluate this approach, two {sup 57}Co flood sources were scanned with a clinical PET/CT multiple times over a period of months. The {sup 56}Co and {sup 58}Co activity was clearly visible in the reconstructed PET images. Total impurity activity was quantified from the PET images after background subtraction of prompt gamma coincidences. Results: Time-of-flight PET reconstruction was highly beneficial for accurate image quantification. Repeated measurements of the positron-emitting impurities showed excellent agreement with an exponential decay model. For both flood sources studied, the fit parameters indicated a zero intercept and a decay half-life consistent with a mixture of {sup 56}Co and {sup 58}Co. The total impurity activity at the reference date was estimated to be 0.06% and 0.07% for the two sources, which was consistent with the vendor’s specification of <0.12%. Conclusions: The robustness of the repeated measurements and a thorough analysis of the detector corrections and physics suggest that the accuracy is acceptable and that the technique is feasible. Further work is needed to validate the accuracy of this technique with a calibrated high resolution gamma spectrometer as a gold standard, which was not available for this study, and for other PET detector models.« less

Fuzzy logic control of an AGV

NASA Astrophysics Data System (ADS)

Kelkar, Nikhal; Samu, Tayib; Hall, Ernest L.

1997-09-01

Automated guided vehicles (AGVs) have many potential applications in manufacturing, medicine, space and defense. The purpose of this paper is to describe exploratory research on the design of a modular autonomous mobile robot controller. The controller incorporates a fuzzy logic approach for steering and speed control, a neuro-fuzzy approach for ultrasound sensing (not discussed in this paper) and an overall expert system. The advantages of a modular system are related to portability and transportability, i.e. any vehicle can become autonomous with minimal modifications. A mobile robot test-bed has been constructed using a golf cart base. This cart has full speed control with guidance provided by a vision system and obstacle avoidance using ultrasonic sensors. The speed and steering fuzzy logic controller is supervised by a 486 computer through a multi-axis motion controller. The obstacle avoidance system is based on a micro-controller interfaced with six ultrasonic transducers. This micro- controller independently handles all timing and distance calculations and sends a steering angle correction back to the computer via the serial line. This design yields a portable independent system in which high speed computer communication is not necessary. Vision guidance is accomplished with a CCD camera with a zoom lens. The data is collected by a vision tracking device that transmits the X, Y coordinates of the lane marker to the control computer. Simulation and testing of these systems yielded promising results. This design, in its modularity, creates a portable autonomous fuzzy logic controller applicable to any mobile vehicle with only minor adaptations.

Development of a mobile robot for the 1995 AUVS competition

NASA Astrophysics Data System (ADS)

Matthews, Bradley O.; Ruthemeyer, Michael A.; Perdue, David; Hall, Ernest L.

1995-12-01

Automated guided vehicles (AGVs) have many potential applications in manufacturing, medicine, space and defense. The purpose of this paper is to describe exploratory research on the design of a modular autonomous mobile robot controller. The advantages of a modular system are related to portability and the fact that any vehicle can become autonomous with minimal modifications. A mobile robot test-bed has been constructed using a golf cart base. This cart has full speed control with guidance provided by a vision system and obstacle avoidance using ultrasonic sensors systems. The speed and steering control are supervised by a 486 computer through a 3-axis motion controller. The obstacle avoidance system is based on a micro-controller interfaced with six ultrasonic transducers. The is micro-controller independently handles all timing and distance calculations and sends a steering angle correction back to the computer via the serial line. This design yields a portable independent system, where even computer communication is not necessary. Vision guidance is accomplished with a CCD camera with a zoom lens. The data is collected through a commercial tracking device, communicating with the computer the X,Y coordinates of the lane marker. Testing of these systems yielded positive results by showing that at five mph the vehicle can follow a line and at the same time avoid obstacles. This design, in its modularity, creates a portable autonomous controller applicable for any mobile vehicle with only minor adaptations.

System for critical infrastructure security based on multispectral observation-detection module

NASA Astrophysics Data System (ADS)

Trzaskawka, Piotr; Kastek, Mariusz; Życzkowski, Marek; Dulski, Rafał; Szustakowski, Mieczysław; Ciurapiński, Wiesław; Bareła, Jarosław

2013-10-01

Recent terrorist attacks and possibilities of such actions in future have forced to develop security systems for critical infrastructures that embrace sensors technologies and technical organization of systems. The used till now perimeter protection of stationary objects, based on construction of a ring with two-zone fencing, visual cameras with illumination are efficiently displaced by the systems of the multisensor technology that consists of: visible technology - day/night cameras registering optical contrast of a scene, thermal technology - cheap bolometric cameras recording thermal contrast of a scene and active ground radars - microwave and millimetre wavelengths that record and detect reflected radiation. Merging of these three different technologies into one system requires methodology for selection of technical conditions of installation and parameters of sensors. This procedure enables us to construct a system with correlated range, resolution, field of view and object identification. Important technical problem connected with the multispectral system is its software, which helps couple the radar with the cameras. This software can be used for automatic focusing of cameras, automatic guiding cameras to an object detected by the radar, tracking of the object and localization of the object on the digital map as well as target identification and alerting. Based on "plug and play" architecture, this system provides unmatched flexibility and simplistic integration of sensors and devices in TCP/IP networks. Using a graphical user interface it is possible to control sensors and monitor streaming video and other data over the network, visualize the results of data fusion process and obtain detailed information about detected intruders over a digital map. System provide high-level applications and operator workload reduction with features such as sensor to sensor cueing from detection devices, automatic e-mail notification and alarm triggering. The paper presents a structure and some elements of critical infrastructure protection solution which is based on a modular multisensor security system. System description is focused mainly on methodology of selection of sensors parameters. The results of the tests in real conditions are also presented.

Gamma-ray detectors for breast imaging

NASA Astrophysics Data System (ADS)

Williams, Mark B.; Goode, Allen R.; Majewski, Stan; Steinbach, Daniela; Weisenberger, Andrew G.; Wojcik, Randolph F.; Farzanpay, Farzin

1997-07-01

Breast cancer is the most common cancer of American women and is the leading cause of cancer-related death among women aged 15 - 54; however recent years have shown that early detection using x-ray mammography can lead to a high probability of cure. However, because of mammography's low positive predictive value, surgical or core biopsy is typically required for diagnosis. In addition, the low radiographic contrast of many nonpalpable breast masses, particularly among women with radiographically dense breasts, results in an overall rate of 10% to 25% for missed tumors. Nuclear imaging of the breast using single gamma emitters (scintimammography) such as (superscript 99m)Tc, or positron emitters such as F-18- fluorodeoxyglucose (FDG) for positron emission tomography (PET), can provide information on functional or metabolic tumor activity that is complementary to the structural information of x-ray mammography, thereby potentially reducing the number of unnecessary biopsies and missed cancers. This paper summarizes recent data on the efficacy of scintimammography using conventional gamma cameras, and describes the development of dedicated detectors for gamma emission breast imaging. The detectors use new, high density crystal scintillators and large area position sensitive photomultiplier tubes (PSPMTs). Detector design, imaging requirements, and preliminary measured imaging performance are discussed.

The optical design of a far infrared imaging FTS for SPICA

NASA Astrophysics Data System (ADS)

Pastor, Carmen; Zuluaga, Pablo; Jellema, Willem; González Fernández, Luis Miguel; Belenguer, Tomas; Torres Redondo, Josefina; Kooijman, Peter Paul; Najarro, Francisco; Eggens, Martin; Roelfsema, Peter; Nakagawa, Takao

2014-08-01

This paper describes the optical design of the far infrared imaging spectrometer for the JAXA's SPICA mission. The SAFARI instrument, is a cryogenic imaging Fourier transform spectrometer (iFTS), designed to perform backgroundlimited spectroscopic and photometric imaging in the band 34-210 μm. The all-reflective optical system is highly modular and consists of three main modules; input optics module, interferometer module (FTS) and camera bay optics. A special study has been dedicated to the spectroscopic performance of the instrument, in which the spectral response and interference of the instrument have been modeled, as the FTS mechanism scans over the total desired OPD range.

Neural Imaging Using Single-Photon Avalanche Diodes

PubMed Central

Karami, Mohammad Azim; Ansarian, Misagh

2017-01-01

Introduction: This paper analyses the ability of single-photon avalanche diodes (SPADs) for neural imaging. The current trend in the production of SPADs moves toward the minimum dark count rate (DCR) and maximum photon detection probability (PDP). Moreover, the jitter response which is the main measurement characteristic for the timing uncertainty is progressing. Methods: The neural imaging process using SPADs can be performed by means of florescence lifetime imaging (FLIM), time correlated single-photon counting (TCSPC), positron emission tomography (PET), and single-photon emission computed tomography (SPECT). Results: This trend will result in more precise neural imaging cameras. While achieving low DCR SPADs is difficult in deep submicron technologies because of using higher doping profiles, higher PDPs are reported in green and blue part of light. Furthermore, the number of pixels integrated in the same chip is increasing with the technology progress which can result in the higher resolution of imaging. Conclusion: This study proposes implemented SPADs in Deep-submicron technologies to be used in neural imaging cameras, due to the small size pixels and higher timing accuracies. PMID:28446946

Gamma-Ray Imaging for Explosives Detection

NASA Technical Reports Server (NTRS)

deNolfo, G. A.; Hunter, S. D.; Barbier, L. M.; Link, J. T.; Son, S.; Floyd, S. R.; Guardala, N.; Skopec, M.; Stark, B.

2008-01-01

We describe a gamma-ray imaging camera (GIC) for active interrogation of explosives being developed by NASA/GSFC and NSWCICarderock. The GIC is based on the Three-dimensional Track Imager (3-DTI) technology developed at GSFC for gamma-ray astrophysics. The 3-DTI, a large volume time-projection chamber, provides accurate, approx.0.4 mm resolution, 3-D tracking of charged particles. The incident direction of gamma rays, E, > 6 MeV, are reconstructed from the momenta and energies of the electron-positron pair resulting from interactions in the 3-DTI volume. The optimization of the 3-DTI technology for this specific application and the performance of the GIC from laboratory tests is presented.

Cerebral perfusion imaging in Alzheimer's disease. Use of single photon emission computed tomography and iofetamine hydrochloride I 123

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, K.A.; Mueller, S.T.; Walshe, T.M.

1987-02-01

We used single photon emission computed tomography (SPECT) to study 15 patients with Alzheimer's disease and nine controls. Iofetamine hydrochloride I 123 uptake data were recorded from the entire brain using a rotating gamma camera. Activity ratios were measured for the frontal, posterior parietal, posterior, medial, and lateral cortical temporal regions and striate cortex and were normalized by the activity in the cerebellum. Abnormalities in iofetamine hydrochloride I 123 activity were similar to the abnormalities in glucose metabolism observed with positron emission tomography. Cortical tracer activity was globally depressed in patients with Alzheimer's disease, with the greatest reduction in themore » posterior parietal cortex.« less

The Beagle 2 Stereo Camera System: Scientific Objectives and Design Characteristics

NASA Astrophysics Data System (ADS)

Griffiths, A.; Coates, A.; Josset, J.; Paar, G.; Sims, M.

2003-04-01

The Stereo Camera System (SCS) will provide wide-angle (48 degree) multi-spectral stereo imaging of the Beagle 2 landing site in Isidis Planitia with an angular resolution of 0.75 milliradians. Based on the SpaceX Modular Micro-Imager, the SCS is composed of twin cameras (with 1024 by 1024 pixel frame transfer CCD) and twin filter wheel units (with a combined total of 24 filters). The primary mission objective is to construct a digital elevation model of the area in reach of the lander’s robot arm. The SCS specifications and following baseline studies are described: Panoramic RGB colour imaging of the landing site and panoramic multi-spectral imaging at 12 distinct wavelengths to study the mineralogy of landing site. Solar observations to measure water vapour absorption and the atmospheric dust optical density. Also envisaged are multi-spectral observations of Phobos &Deimos (observations of the moons relative to background stars will be used to determine the lander’s location and orientation relative to the Martian surface), monitoring of the landing site to detect temporal changes, observation of the actions and effects of the other PAW experiments (including rock texture studies with a close-up-lens) and collaborative observations with the Mars Express orbiter instrument teams. Due to be launched in May of this year, the total system mass is 360 g, the required volume envelope is 747 cm^3 and the average power consumption is 1.8 W. A 10Mbit/s RS422 bus connects each camera to the lander common electronics.

SeeStar: an open-source, low-cost imaging system for subsea observations

NASA Astrophysics Data System (ADS)

Cazenave, F.; Kecy, C. D.; Haddock, S.

2016-02-01

Scientists and engineers at the Monterey Bay Aquarium Research Institute (MBARI) have collaborated to develop SeeStar, a modular, light weight, self-contained, low-cost subsea imaging system for short- to long-term monitoring of marine ecosystems. SeeStar is composed of separate camera, battery, and LED lighting modules. Two versions of the system exist: one rated to 300 meters depth, the other rated to 1500 meters. Users can download plans and instructions from an online repository and build the system using low-cost off-the-shelf components. The system utilizes an easily programmable Arduino based controller, and the widely distributed GoPro camera. The system can be deployed in a variety of scenarios taking still images and video and can be operated either autonomously or tethered on a range of platforms, including ROVs, AUVs, landers, piers, and moorings. Several Seestar systems have been built and used for scientific studies and engineering tests. The long-term goal of this project is to have a widely distributed marine imaging network across thousands of locations, to develop baselines of biological information.

Tomographic Small-Animal Imaging Using a High-Resolution Semiconductor Camera

PubMed Central

Kastis, GA; Wu, MC; Balzer, SJ; Wilson, DW; Furenlid, LR; Stevenson, G; Barber, HB; Barrett, HH; Woolfenden, JM; Kelly, P; Appleby, M

2015-01-01

We have developed a high-resolution, compact semiconductor camera for nuclear medicine applications. The modular unit has been used to obtain tomographic images of phantoms and mice. The system consists of a 64 x 64 CdZnTe detector array and a parallel-hole tungsten collimator mounted inside a 17 cm x 5.3 cm x 3.7 cm tungsten-aluminum housing. The detector is a 2.5 cm x 2.5 cm x 0.15 cm slab of CdZnTe connected to a 64 x 64 multiplexer readout via indium-bump bonding. The collimator is 7 mm thick, with a 0.38 mm pitch that matches the detector pixel pitch. We obtained a series of projections by rotating the object in front of the camera. The axis of rotation was vertical and about 1.5 cm away from the collimator face. Mouse holders were made out of acrylic plastic tubing to facilitate rotation and the administration of gas anesthetic. Acquisition times were varied from 60 sec to 90 sec per image for a total of 60 projections at an equal spacing of 6 degrees between projections. We present tomographic images of a line phantom and mouse bone scan and assess the properties of the system. The reconstructed images demonstrate spatial resolution on the order of 1–2 mm. PMID:26568676

Automatic image database generation from CAD for 3D object recognition

NASA Astrophysics Data System (ADS)

Sardana, Harish K.; Daemi, Mohammad F.; Ibrahim, Mohammad K.

1993-06-01

The development and evaluation of Multiple-View 3-D object recognition systems is based on a large set of model images. Due to the various advantages of using CAD, it is becoming more and more practical to use existing CAD data in computer vision systems. Current PC- level CAD systems are capable of providing physical image modelling and rendering involving positional variations in cameras, light sources etc. We have formulated a modular scheme for automatic generation of various aspects (views) of the objects in a model based 3-D object recognition system. These views are generated at desired orientations on the unit Gaussian sphere. With a suitable network file sharing system (NFS), the images can directly be stored on a database located on a file server. This paper presents the image modelling solutions using CAD in relation to multiple-view approach. Our modular scheme for data conversion and automatic image database storage for such a system is discussed. We have used this approach in 3-D polyhedron recognition. An overview of the results, advantages and limitations of using CAD data and conclusions using such as scheme are also presented.

SCORPION II persistent surveillance system update

NASA Astrophysics Data System (ADS)

Coster, Michael; Chambers, Jon

2010-04-01

This paper updates the improvements and benefits demonstrated in the next generation Northrop Grumman SCORPION II family of persistent surveillance and target recognition systems produced by the Xetron Campus in Cincinnati, Ohio. SCORPION II reduces the size, weight, and cost of all SCORPION components in a flexible, field programmable system that is easier to conceal and enables integration of over fifty different Unattended Ground Sensor (UGS) and camera types from a variety of manufacturers, with a modular approach to supporting multiple Line of Sight (LOS) and Beyond Line of Sight (BLOS) communications interfaces. Since 1998 Northrop Grumman has been integrating best in class sensors with its proven universal modular Gateway to provide encrypted data exfiltration to Common Operational Picture (COP) systems and remote sensor command and control. In addition to feeding COP systems, SCORPION and SCORPION II data can be directly processed using a common sensor status graphical user interface (GUI) that allows for viewing and analysis of images and sensor data from up to seven hundred SCORPION system gateways on single or multiple displays. This GUI enables a large amount of sensor data and imagery to be used for actionable intelligence as well as remote sensor command and control by a minimum number of analysts.

The System Design, Engineering Architecture, and Preliminary Results of a Lower-Cost High-Sensitivity High-Resolution Positron Emission Mammography Camera.

PubMed

Zhang, Yuxuan; Ramirez, Rocio A; Li, Hongdi; Liu, Shitao; An, Shaohui; Wang, Chao; Baghaei, Hossain; Wong, Wai-Hoi

2010-02-01

A lower-cost high-sensitivity high-resolution positron emission mammography (PEM) camera is developed. It consists of two detector modules with the planar detector bank of 20 × 12 cm(2). Each bank has 60 low-cost PMT-Quadrant-Sharing (PQS) LYSO blocks arranged in a 10 × 6 array with two types of geometries. One is the symmetric 19.36 × 19.36 mm(2) block made of 1.5 × 1.5 × 10 mm(3) crystals in a 12 × 12 array. The other is the 19.36 × 26.05 mm(2) asymmetric block made of 1.5 × 1.9 × 10 mm(3) crystals in 12 × 13 array. One row (10) of the elongated blocks are used along one side of the bank to reclaim the half empty PMT photocathode in the regular PQS design to reduce the dead area at the edge of the module. The bank has a high overall crystal packing fraction of 88%, which results in a very high sensitivity. Mechanical design and electronics have been developed for low-cost, compactness, and stability purposes. Each module has four Anger-HYPER decoding electronics that can handle a count-rate of 3 Mcps for single events. A simple two-module coincidence board with a hardware delay window for random coincidences has been developed with an adjustable window of 6 to 15 ns. Some of the performance parameters have been studied by preliminary tests and Monte Carlo simulations, including the crystal decoding map and the 17% energy resolution of the detectors, the point source sensitivity of 11.5% with 50 mm bank-to-bank distance, the 1.2 mm-spatial resolutions, 42 kcps peak Noise Equivalent Count Rate at 7.0-mCi total activity in human body, and the resolution phantom images. Those results show that the design goal of building a lower-cost, high-sensitivity, high-resolution PEM detector is achieved.

Development and Operation of a High Resolution Positron Emission Tomography System to Perform Metabolic Studies on Small Animals.

NASA Astrophysics Data System (ADS)

Hogan, Matthew John

A positron emission tomography system designed to perform high resolution imaging of small volumes has been characterized. Two large area planar detectors, used to detect the annihilation gamma rays, formed a large aperture stationary positron camera. The detectors were multiwire proportional chambers coupled to high density lead stack converters. Detector efficiency was 8%. The coincidence resolving time was 500 nsec. The maximum system sensitivity was 60 cps/(mu)Ci for a solid angle of acceptance of 0.74(pi) St. The maximum useful coincidence count rate was 1500 cps and was limited by electronic dead time. Image reconstruction was done by performing a 3-dimensional deconvolution using Fourier transform methods. Noise propagation during reconstruction was minimized by choosing a 'minimum norm' reconstructed image. In the stationary detector system (with a limited angle of acceptance for coincident events) statistical uncertainty in the data limited reconstruction in the direction normal to the detector surfaces. Data from a rotated phantom showed that detector rotation will correct this problem. Resolution was 4 mm in planes parallel to the detectors and (TURN)15 mm in the normal direction. Compton scattering of gamma rays within a source distribution was investigated using both simulated and measured data. Attenuation due to scatter was as high as 60%. For small volume imaging the Compton background was identified and an approximate correction was performed. A semiquantitative blood flow measurement to bone in the leg of a cat using the ('18)F('-) ion was performed. The results were comparable to investigations using more conventional techniques. Qualitative scans using ('18)F labelled deoxy -D-glucose to assess brain glucose metabolism in a rhesus monkey were also performed.

Positron emission tomography: a novel technique for investigating the biodistribution and transport of nanoparticles.

PubMed

Palko, Heather A; Fung, Jennifer Y; Louie, Angelique Y

2010-07-01

Particulate matter (PM) has been associated with serious health effects within but also outside of the pulmonary system. Therefore, there is great interest in studying the biodistribution of PM after delivery to the lung to correlate sites of extrapulmonary particle accumulation and abnormal conditions known to be associated with PM exposure. Traditional PM tracking studies have introduced nanoparticles to animal models or humans and have determined the biodistribution with gamma counting, gamma camera, and inductively coupled plasma mass spectrometry (ICP-MS). The authors here demonstrate that positron emission tomography (PET) is a powerful tool that can be employed to visualize the deposition and track the fate of nanoparticles in the mouse model. In these studies, approximately 100-nm polystyrene nanoparticles were labeled with the positron emitter 64Cu bound by the chelator (S)-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-tetraacetic acid (p-SCN-Bn-DOTA). The labeled nanoparticles were instilled intratracheally into C57BL/6 mice; the initial deposition and biodistribution through 48 h was determined by PET imaging. In addition to static imaging, dynamic imaging was performed in the Sprague-Dawley rat model to demonstrate that PET can capture particle movement in pseudo-time-lapse videos. Particle deposition and clearance was clearly identified by PET, and the same animals could be imaged repeatedly without any adverse effects from anesthesia. PET has the potential to require many fewer animals than traditional methods while still providing quantitative results. In addition, the initial deposition pattern in each animal can be accurately determined and the same animal monitored over time so that data interpretation is not clouded by variations in initial deposition profiles.

TestDose: A nuclear medicine software based on Monte Carlo modeling for generating gamma camera acquisitions and dosimetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia, Marie-Paule, E-mail: marie-paule.garcia@univ-brest.fr; Villoing, Daphnée; McKay, Erin

Purpose: The TestDose platform was developed to generate scintigraphic imaging protocols and associated dosimetry by Monte Carlo modeling. TestDose is part of a broader project (www.dositest.com) whose aim is to identify the biases induced by different clinical dosimetry protocols. Methods: The TestDose software allows handling the whole pipeline from virtual patient generation to resulting planar and SPECT images and dosimetry calculations. The originality of their approach relies on the implementation of functional segmentation for the anthropomorphic model representing a virtual patient. Two anthropomorphic models are currently available: 4D XCAT and ICRP 110. A pharmacokinetic model describes the biodistribution of amore » given radiopharmaceutical in each defined compartment at various time-points. The Monte Carlo simulation toolkit GATE offers the possibility to accurately simulate scintigraphic images and absorbed doses in volumes of interest. The TestDose platform relies on GATE to reproduce precisely any imaging protocol and to provide reference dosimetry. For image generation, TestDose stores user’s imaging requirements and generates automatically command files used as input for GATE. Each compartment is simulated only once and the resulting output is weighted using pharmacokinetic data. Resulting compartment projections are aggregated to obtain the final image. For dosimetry computation, emission data are stored in the platform database and relevant GATE input files are generated for the virtual patient model and associated pharmacokinetics. Results: Two samples of software runs are given to demonstrate the potential of TestDose. A clinical imaging protocol for the Octreoscan™ therapeutical treatment was implemented using the 4D XCAT model. Whole-body “step and shoot” acquisitions at different times postinjection and one SPECT acquisition were generated within reasonable computation times. Based on the same Octreoscan™ kinetics, a dosimetry computation performed on the ICRP 110 model is also presented. Conclusions: The proposed platform offers a generic framework to implement any scintigraphic imaging protocols and voxel/organ-based dosimetry computation. Thanks to the modular nature of TestDose, other imaging modalities could be supported in the future such as positron emission tomography.« less

TestDose: A nuclear medicine software based on Monte Carlo modeling for generating gamma camera acquisitions and dosimetry.

PubMed

Garcia, Marie-Paule; Villoing, Daphnée; McKay, Erin; Ferrer, Ludovic; Cremonesi, Marta; Botta, Francesca; Ferrari, Mahila; Bardiès, Manuel

2015-12-01

The TestDose platform was developed to generate scintigraphic imaging protocols and associated dosimetry by Monte Carlo modeling. TestDose is part of a broader project (www.dositest.com) whose aim is to identify the biases induced by different clinical dosimetry protocols. The TestDose software allows handling the whole pipeline from virtual patient generation to resulting planar and SPECT images and dosimetry calculations. The originality of their approach relies on the implementation of functional segmentation for the anthropomorphic model representing a virtual patient. Two anthropomorphic models are currently available: 4D XCAT and ICRP 110. A pharmacokinetic model describes the biodistribution of a given radiopharmaceutical in each defined compartment at various time-points. The Monte Carlo simulation toolkit gate offers the possibility to accurately simulate scintigraphic images and absorbed doses in volumes of interest. The TestDose platform relies on gate to reproduce precisely any imaging protocol and to provide reference dosimetry. For image generation, TestDose stores user's imaging requirements and generates automatically command files used as input for gate. Each compartment is simulated only once and the resulting output is weighted using pharmacokinetic data. Resulting compartment projections are aggregated to obtain the final image. For dosimetry computation, emission data are stored in the platform database and relevant gate input files are generated for the virtual patient model and associated pharmacokinetics. Two samples of software runs are given to demonstrate the potential of TestDose. A clinical imaging protocol for the Octreoscan™ therapeutical treatment was implemented using the 4D XCAT model. Whole-body "step and shoot" acquisitions at different times postinjection and one SPECT acquisition were generated within reasonable computation times. Based on the same Octreoscan™ kinetics, a dosimetry computation performed on the ICRP 110 model is also presented. The proposed platform offers a generic framework to implement any scintigraphic imaging protocols and voxel/organ-based dosimetry computation. Thanks to the modular nature of TestDose, other imaging modalities could be supported in the future such as positron emission tomography.

Toward VIP-PIX: A Low Noise Readout ASIC for Pixelated CdTe Gamma-Ray Detectors for Use in the Next Generation of PET Scanners.

PubMed

Macias-Montero, Jose-Gabriel; Sarraj, Maher; Chmeissani, Mokhtar; Puigdengoles, Carles; Lorenzo, Gianluca De; Martínez, Ricardo

2013-08-01

VIP-PIX will be a low noise and low power pixel readout electronics with digital output for pixelated Cadmium Telluride (CdTe) detectors. The proposed pixel will be part of a 2D pixel-array detector for various types of nuclear medicine imaging devices such as positron-emission tomography (PET) scanners, Compton gamma cameras, and positron-emission mammography (PEM) scanners. Each pixel will include a SAR ADC that provides the energy deposited with 10-bit resolution. Simultaneously, the self-triggered pixel which will be connected to a global time-to-digital converter (TDC) with 1 ns resolution will provide the event's time stamp. The analog part of the readout chain and the ADC have been fabricated with TSMC 0.25 μ m mixed-signal CMOS technology and characterized with an external test pulse. The power consumption of these parts is 200 μ W from a 2.5 V supply. It offers 4 switchable gains from ±10 mV/fC to ±40 mV/fC and an input charge dynamic range of up to ±70 fC for the minimum gain for both polarities. Based on noise measurements, the expected equivalent noise charge (ENC) is 65 e - RMS at room temperature.

Development of dose delivery verification by PET imaging of photonuclear reactions following high energy photon therapy

NASA Astrophysics Data System (ADS)

Janek, S.; Svensson, R.; Jonsson, C.; Brahme, A.

2006-11-01

A method for dose delivery monitoring after high energy photon therapy has been investigated based on positron emission tomography (PET). The technique is based on the activation of body tissues by high energy bremsstrahlung beams, preferably with energies well above 20 MeV, resulting primarily in 11C and 15O but also 13N, all positron-emitting radionuclides produced by photoneutron reactions in the nuclei of 12C, 16O and 14N. A PMMA phantom and animal tissue, a frozen hind leg of a pig, were irradiated to 10 Gy and the induced positron activity distributions were measured off-line in a PET camera a couple of minutes after irradiation. The accelerator used was a Racetrack Microtron at the Karolinska University Hospital using 50 MV scanned photon beams. From photonuclear cross-section data integrated over the 50 MV photon fluence spectrum the predicted PET signal was calculated and compared with experimental measurements. Since measured PET images change with time post irradiation, as a result of the different decay times of the radionuclides, the signals from activated 12C, 16O and 14N within the irradiated volume could be separated from each other. Most information is obtained from the carbon and oxygen radionuclides which are the most abundant elements in soft tissue. The predicted and measured overall positron activities are almost equal (-3%) while the predicted activity originating from nitrogen is overestimated by almost a factor of two, possibly due to experimental noise. Based on the results obtained in this first feasibility study the great value of a combined radiotherapy-PET-CT unit is indicated in order to fully exploit the high activity signal from oxygen immediately after treatment and to avoid patient repositioning. With an RT-PET-CT unit a high signal could be collected even at a dose level of 2 Gy and the acquisition time for the PET could be reduced considerably. Real patient dose delivery verification by means of PET imaging seems to be applicable provided that biological transport processes such as capillary blood flow containing mobile 15O and 11C in the activated tissue volume can be accounted for.

The €100 lab: A 3D-printable open-source platform for fluorescence microscopy, optogenetics, and accurate temperature control during behaviour of zebrafish, Drosophila, and Caenorhabditis elegans

PubMed Central

Maia Chagas, Andre; Prieto-Godino, Lucia L.; Arrenberg, Aristides B.

2017-01-01

Small, genetically tractable species such as larval zebrafish, Drosophila, or Caenorhabditis elegans have become key model organisms in modern neuroscience. In addition to their low maintenance costs and easy sharing of strains across labs, one key appeal is the possibility to monitor single or groups of animals in a behavioural arena while controlling the activity of select neurons using optogenetic or thermogenetic tools. However, the purchase of a commercial solution for these types of experiments, including an appropriate camera system as well as a controlled behavioural arena, can be costly. Here, we present a low-cost and modular open-source alternative called ‘FlyPi’. Our design is based on a 3D-printed mainframe, a Raspberry Pi computer, and high-definition camera system as well as Arduino-based optical and thermal control circuits. Depending on the configuration, FlyPi can be assembled for well under €100 and features optional modules for light-emitting diode (LED)-based fluorescence microscopy and optogenetic stimulation as well as a Peltier-based temperature stimulator for thermogenetics. The complete version with all modules costs approximately €200 or substantially less if the user is prepared to ‘shop around’. All functions of FlyPi can be controlled through a custom-written graphical user interface. To demonstrate FlyPi’s capabilities, we present its use in a series of state-of-the-art neurogenetics experiments. In addition, we demonstrate FlyPi’s utility as a medical diagnostic tool as well as a teaching aid at Neurogenetics courses held at several African universities. Taken together, the low cost and modular nature as well as fully open design of FlyPi make it a highly versatile tool in a range of applications, including the classroom, diagnostic centres, and research labs. PMID:28719603

The €100 lab: A 3D-printable open-source platform for fluorescence microscopy, optogenetics, and accurate temperature control during behaviour of zebrafish, Drosophila, and Caenorhabditis elegans.

PubMed

Maia Chagas, Andre; Prieto-Godino, Lucia L; Arrenberg, Aristides B; Baden, Tom

2017-07-01

Small, genetically tractable species such as larval zebrafish, Drosophila, or Caenorhabditis elegans have become key model organisms in modern neuroscience. In addition to their low maintenance costs and easy sharing of strains across labs, one key appeal is the possibility to monitor single or groups of animals in a behavioural arena while controlling the activity of select neurons using optogenetic or thermogenetic tools. However, the purchase of a commercial solution for these types of experiments, including an appropriate camera system as well as a controlled behavioural arena, can be costly. Here, we present a low-cost and modular open-source alternative called 'FlyPi'. Our design is based on a 3D-printed mainframe, a Raspberry Pi computer, and high-definition camera system as well as Arduino-based optical and thermal control circuits. Depending on the configuration, FlyPi can be assembled for well under €100 and features optional modules for light-emitting diode (LED)-based fluorescence microscopy and optogenetic stimulation as well as a Peltier-based temperature stimulator for thermogenetics. The complete version with all modules costs approximately €200 or substantially less if the user is prepared to 'shop around'. All functions of FlyPi can be controlled through a custom-written graphical user interface. To demonstrate FlyPi's capabilities, we present its use in a series of state-of-the-art neurogenetics experiments. In addition, we demonstrate FlyPi's utility as a medical diagnostic tool as well as a teaching aid at Neurogenetics courses held at several African universities. Taken together, the low cost and modular nature as well as fully open design of FlyPi make it a highly versatile tool in a range of applications, including the classroom, diagnostic centres, and research labs.

DESIGN, CONSTRUCTION AND FIELD DEMONSTRATION OF EXPLORER: A LONG-RANGE UNTETHERED LIVE GASLINE INSPECTION ROBOT SYSTEM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dr. George C. Vradis; Dr. Hagen Schempf

2003-04-01

This program is undertaken in order to construct and field-demonstrate EXPLORER, a modular, remotely controllable, self-powered, untethered robot system for the inspection of live gas distribution 150 mm (6-inch) to 200 mm (8-inch) diameter mains. The modular design of the system allows it to accommodate various components intended to accomplish different inspection, repair, sample retrieval, and other in-pipe tasks. The prototype system being built under this project will include all the basic modules needed, i.e. the locomotor, power storage, wireless communication, and camera. The camera, a solid-state fisheye-type, is used to transmit real-time video to the operator that allows formore » the live inspection of gas distribution pipes. This module, which incorporates technology developed by NASA, has already been designed, constructed and tested, having exceeded performance expectations. The full prototype system will be comprehensively tested in the laboratory followed by two field demonstrations in real applications in NGA member utilities' pipes. The system under development significantly advances the state of the art in inspection systems for gas distribution mains, which presently consist of tethered systems of limited range (about 500 ft form the point of launch) and limited inspection views. Also current inspection systems have no ability to incorporate additional modules to expand their functionality. The present report summarizes the accomplishments of the project during its third six-month period. The project has in general achieved its goals for this period as outlined in the report. The fabrication of the prototype is complete and is now been tested in the laboratory mainly focusing on the last system integration issues and on software development for the turning and launching routines. Testing of the prototype in the lab is expected to be completed by Summer 2003, to be followed by two field demonstrations in early Fall 2003.« less

Fast Pb-glass neutron-to-light converter for ICF (Inertial Confinement Fusion) target burn history measurements

NASA Astrophysics Data System (ADS)

Lerche, R. A.; Cable, M. D.; Phillion, D. W.

1990-09-01

We are developing a streak camera based instrument to diagnose the fusion reaction rate (burn history) within laser-driven ICF targets filled with D-T fuel. Recently, we attempted measurements using the 16.7 MeV gamma ray emitted in the T(d,gamma)He(5) fusion reaction. Pb glass which has a large cross section for pair production acts as a gamma-ray-to-light converter. Gamma rays interact within the glass to form electron-positron pairs that produce large amounts (1000 photons/gamma ray) of prompt (less than 10 ps) Cerenkov light as they slow down. In our experimental instrument, an f/10 Cassegrain telescope optically couples light produced within the converter to a streak camera having 20-ps resolution. Experiments using high-yield (10(exp 13) D-T neutrons), direct-drive targets at Nova produced good signals with widths of 200 ps. Time-of-flight measurements show the signals to be induced by neutrons rather than gamma rays. The Pb glass appears to act as a fast neutron-to-light converter. We continue to study the interactions process and the possibility of using the 16.7 MeV gamma rays for burn time measurements.

MARS: a mouse atlas registration system based on a planar x-ray projector and an optical camera

NASA Astrophysics Data System (ADS)

Wang, Hongkai; Stout, David B.; Taschereau, Richard; Gu, Zheng; Vu, Nam T.; Prout, David L.; Chatziioannou, Arion F.

2012-10-01

This paper introduces a mouse atlas registration system (MARS), composed of a stationary top-view x-ray projector and a side-view optical camera, coupled to a mouse atlas registration algorithm. This system uses the x-ray and optical images to guide a fully automatic co-registration of a mouse atlas with each subject, in order to provide anatomical reference for small animal molecular imaging systems such as positron emission tomography (PET). To facilitate the registration, a statistical atlas that accounts for inter-subject anatomical variations was constructed based on 83 organ-labeled mouse micro-computed tomography (CT) images. The statistical shape model and conditional Gaussian model techniques were used to register the atlas with the x-ray image and optical photo. The accuracy of the atlas registration was evaluated by comparing the registered atlas with the organ-labeled micro-CT images of the test subjects. The results showed excellent registration accuracy of the whole-body region, and good accuracy for the brain, liver, heart, lungs and kidneys. In its implementation, the MARS was integrated with a preclinical PET scanner to deliver combined PET/MARS imaging, and to facilitate atlas-assisted analysis of the preclinical PET images.

MARS: a mouse atlas registration system based on a planar x-ray projector and an optical camera.

PubMed

Wang, Hongkai; Stout, David B; Taschereau, Richard; Gu, Zheng; Vu, Nam T; Prout, David L; Chatziioannou, Arion F

2012-10-07

This paper introduces a mouse atlas registration system (MARS), composed of a stationary top-view x-ray projector and a side-view optical camera, coupled to a mouse atlas registration algorithm. This system uses the x-ray and optical images to guide a fully automatic co-registration of a mouse atlas with each subject, in order to provide anatomical reference for small animal molecular imaging systems such as positron emission tomography (PET). To facilitate the registration, a statistical atlas that accounts for inter-subject anatomical variations was constructed based on 83 organ-labeled mouse micro-computed tomography (CT) images. The statistical shape model and conditional Gaussian model techniques were used to register the atlas with the x-ray image and optical photo. The accuracy of the atlas registration was evaluated by comparing the registered atlas with the organ-labeled micro-CT images of the test subjects. The results showed excellent registration accuracy of the whole-body region, and good accuracy for the brain, liver, heart, lungs and kidneys. In its implementation, the MARS was integrated with a preclinical PET scanner to deliver combined PET/MARS imaging, and to facilitate atlas-assisted analysis of the preclinical PET images.

MACS-Himalaya: A photogrammetric aerial oblique camera system designed for highly accurate 3D-reconstruction and monitoring in steep terrain and under extreme illumination conditions

NASA Astrophysics Data System (ADS)

Brauchle, Joerg; Berger, Ralf; Hein, Daniel; Bucher, Tilman

2017-04-01

The DLR Institute of Optical Sensor Systems has developed the MACS-Himalaya, a custom built Modular Aerial Camera System specifically designed for the extreme geometric (steep slopes) and radiometric (high contrast) conditions of high mountain areas. It has an overall field of view of 116° across-track consisting of a nadir and two oblique looking RGB camera heads and a fourth nadir looking near-infrared camera. This design provides the capability to fly along narrow valleys and simultaneously cover ground and steep valley flank topography with similar ground resolution. To compensate for extreme contrasts between fresh snow and dark shadows in high altitudes a High Dynamic Range (HDR) mode was implemented, which typically takes a sequence of 3 images with graded integration times, each covering 12 bit radiometric depth, resulting in a total dynamic range of 15-16 bit. This enables dense image matching and interpretation for sunlit snow and glaciers as well as for dark shaded rock faces in the same scene. Small and lightweight industrial grade camera heads are used and operated at a rate of 3.3 frames per second with 3-step HDR, which is sufficient to achieve a longitudinal overlap of approximately 90% per exposure time at 1,000 m above ground at a velocity of 180 km/h. Direct georeferencing and multitemporal monitoring without the need of ground control points is possible due to the use of a high end GPS/INS system, a stable calibrated inner geometry of the camera heads and a fully photogrammetric workflow at DLR. In 2014 a survey was performed on the Nepalese side of the Himalayas. The remote sensing system was carried in a wingpod by a Stemme S10 motor glider. Amongst other targets, the Seti Valley, Kali-Gandaki Valley and the Mt. Everest/Khumbu Region were imaged at altitudes up to 9,200 m. Products such as dense point clouds, DSMs and true orthomosaics with a ground pixel resolution of up to 15 cm were produced in regions and outcrops normally inaccessible to aerial imagery. These data are used in the fields of natural hazards, geomorphology and glaciology (see Thompson et al., CR4.3). In the presentation the camera system is introduced and examples and applications from the Nepal campaign are given.

Neutrino energy transport in weak decoupling and big bang nucleosynthesis

DOE PAGES

Grohs, Evan Bradley; Paris, Mark W.; Kishimoto, Chad T.; ...

2016-04-21

In this study, we calculate the evolution of the early universe through the epochs of weak decoupling, weak freeze-out and big bang nucleosynthesis (BBN) by simultaneously coupling a full strong, electromagnetic, and weak nuclear reaction network with a multienergy group Boltzmann neutrino energy transport scheme. The modular structure of our code provides the ability to dissect the relative contributions of each process responsible for evolving the dynamics of the early universe in the absence of neutrino flavor oscillations. Such an approach allows a detailed accounting of the evolution of the νe, ν¯e, νμ, ν¯μ, ντ, ν¯τ energy distribution functions alongsidemore » and self-consistently with the nuclear reactions and entropy/heat generation and flow between the neutrino and photon/electron/positron/baryon plasma components. This calculation reveals nonlinear feedback in the time evolution of neutrino distribution functions and plasma thermodynamic conditions (e.g., electron-positron pair densities), with implications for the phasing between scale factor and plasma temperature; the neutron-to-proton ratio; light-element abundance histories; and the cosmological parameter N eff. We find that our approach of following the time development of neutrino spectral distortions and concomitant entropy production and extraction from the plasma results in changes in the computed value of the BBN deuterium yield. For example, for particular implementations of quantum corrections in plasma thermodynamics, our calculations show a 0.4% increase in deuterium. These changes are potentially significant in the context of anticipated improvements in observational and nuclear physics uncertainties.« less

Neutrino energy transport in weak decoupling and big bang nucleosynthesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grohs, Evan Bradley; Paris, Mark W.; Kishimoto, Chad T.

In this study, we calculate the evolution of the early universe through the epochs of weak decoupling, weak freeze-out and big bang nucleosynthesis (BBN) by simultaneously coupling a full strong, electromagnetic, and weak nuclear reaction network with a multienergy group Boltzmann neutrino energy transport scheme. The modular structure of our code provides the ability to dissect the relative contributions of each process responsible for evolving the dynamics of the early universe in the absence of neutrino flavor oscillations. Such an approach allows a detailed accounting of the evolution of the νe, ν¯e, νμ, ν¯μ, ντ, ν¯τ energy distribution functions alongsidemore » and self-consistently with the nuclear reactions and entropy/heat generation and flow between the neutrino and photon/electron/positron/baryon plasma components. This calculation reveals nonlinear feedback in the time evolution of neutrino distribution functions and plasma thermodynamic conditions (e.g., electron-positron pair densities), with implications for the phasing between scale factor and plasma temperature; the neutron-to-proton ratio; light-element abundance histories; and the cosmological parameter N eff. We find that our approach of following the time development of neutrino spectral distortions and concomitant entropy production and extraction from the plasma results in changes in the computed value of the BBN deuterium yield. For example, for particular implementations of quantum corrections in plasma thermodynamics, our calculations show a 0.4% increase in deuterium. These changes are potentially significant in the context of anticipated improvements in observational and nuclear physics uncertainties.« less

INFIBRA: machine vision inspection of acrylic fiber production

NASA Astrophysics Data System (ADS)

Davies, Roger; Correia, Bento A. B.; Contreiras, Jose; Carvalho, Fernando D.

1998-10-01

This paper describes the implementation of INFIBRA, a machine vision system for the inspection of acrylic fiber production lines. The system was developed by INETI under a contract from Fisipe, Fibras Sinteticas de Portugal, S.A. At Fisipe there are ten production lines in continuous operation, each approximately 40 m in length. A team of operators used to perform periodic manual visual inspection of each line in conditions of high ambient temperature and humidity. It is not surprising that failures in the manual inspection process occurred with some frequency, with consequences that ranged from reduced fiber quality to production stoppages. The INFIBRA system architecture is a specialization of a generic, modular machine vision architecture based on a network of Personal Computers (PCs), each equipped with a low cost frame grabber. Each production line has a dedicated PC that performs automatic inspection, using specially designed metrology algorithms, via four video cameras located at key positions on the line. The cameras are mounted inside custom-built, hermetically sealed water-cooled housings to protect them from the unfriendly environment. The ten PCs, one for each production line, communicate with a central PC via a standard Ethernet connection. The operator controls all aspects of the inspection process, from configuration through to handling alarms, via a simple graphical interface on the central PC. At any time the operator can also view on the central PC's screen the live image from any one of the 40 cameras employed by the system.

Development of a composite large-size SiPM (assembled matrix) based modular detector cluster for MAGIC

NASA Astrophysics Data System (ADS)

Hahn, A.; Mazin, D.; Bangale, P.; Dettlaff, A.; Fink, D.; Grundner, F.; Haberer, W.; Maier, R.; Mirzoyan, R.; Podkladkin, S.; Teshima, M.; Wetteskind, H.

2017-02-01

The MAGIC collaboration operates two 17 m diameter Imaging Atmospheric Cherenkov Telescopes (IACTs) on the Canary Island of La Palma. Each of the two telescopes is currently equipped with a photomultiplier tube (PMT) based imaging camera. Due to the advances in the development of Silicon Photomultipliers (SiPMs), they are becoming a widely used alternative to PMTs in many research fields including gamma-ray astronomy. Within the Otto-Hahn group at the Max Planck Institute for Physics, Munich, we are developing a SiPM based detector module for a possible upgrade of the MAGIC cameras and also for future experiments as, e.g., the Large Size Telescopes (LST) of the Cherenkov Telescope Array (CTA). Because of the small size of individual SiPM sensors (6 mm×6 mm) with respect to the 1-inch diameter PMTs currently used in MAGIC, we use a custom-made matrix of SiPMs to cover the same detection area. We developed an electronic circuit to actively sum up and amplify the SiPM signals. Existing non-imaging hexagonal light concentrators (Winston cones) used in MAGIC have been modified for the angular acceptance of the SiPMs by using C++ based ray tracing simulations. The first prototype based detector module includes seven channels and was installed into the MAGIC camera in May 2015. We present the results of the first prototype and its performance as well as the status of the project and discuss its challenges.

Robonaut: A Robotic Astronaut Assistant

NASA Technical Reports Server (NTRS)

Ambrose, Robert O.; Diftler, Myron A.

2001-01-01

NASA's latest anthropomorphic robot, Robonaut, has reached a milestone in its capability. This highly dexterous robot, designed to assist astronauts in space, is now performing complex tasks at the Johnson Space Center that could previously only be carried out by humans. With 43 degrees of freedom, Robonaut is the first humanoid built for space and incorporates technology advances in dexterous hands, modular manipulators, lightweight materials, and telepresence control systems. Robonaut is human size, has a three degree of freedom (DOF) articulated waist, and two, seven DOF arms, giving it an impressive work space for interacting with its environment. Its two, five fingered hands allow manipulation of a wide range of tools. A pan/tilt head with multiple stereo camera systems provides data for both teleoperators and computer vision systems.

Development of a drone equipped with optimized sensors for nuclear and radiological risk characterization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boudergui, K.; Carrel, F.; Domenech, T.

2011-07-01

The MOBISIC project, funded by the Systematic Paris-Region cluster, is being developed in the context of local crisis (attack bombing in urban environment, in confined space such as an underground train tunnel etc.) or specific event securing (soccer world cup, political meeting etc.). It consists in conceiving, developing and experimenting a mobile, modular ('plug and play') and multi-sensors securing system. In this project, CEA LIST has suggested different solutions for nuclear risks detection and identification. It results in embedding a CZT sensor and a gamma camera in an indoor drone. This article first presents the different modifications carried out onmore » the UAV and different sensors, and focuses then on the experimental performances. (authors)« less

New Focal Plane Array Controller for the Instruments of the Subaru Telescope

NASA Astrophysics Data System (ADS)

Nakaya, Hidehiko; Komiyama, Yutaka; Miyazaki, Satoshi; Yamashita, Takuya; Yagi, Masafumi; Sekiguchi, Maki

2006-03-01

We have developed a next-generation data acquisition system, MESSIA5 (Modularized Extensible System for Image Acquisition), which comprises the digital part of a focal plane array controller. The new data acquisition system was constructed based on a 64 bit, 66 MHz PCI (peripheral component interconnect) bus architecture and runs on an x86 CPU computer with (non-real-time) Linux. The system, including the CPU board, is placed at the telescope focus, and standard gigabit Ethernet is adopted for the data transfer, as opposed to a dedicated fiber link. During the summer of 2002, we installed the new system for the first time on the Subaru prime-focus camera Suprime-Cam and successfully improved the observing performance.

Modified modular imaging system designed for a sounding rocket experiment

NASA Astrophysics Data System (ADS)

Veach, Todd J.; Scowen, Paul A.; Beasley, Matthew; Nikzad, Shouleh

2012-09-01

We present the design and system calibration results from the fabrication of a charge-coupled device (CCD) based imaging system designed using a modified modular imager cell (MIC) used in an ultraviolet sounding rocket mission. The heart of the imaging system is the MIC, which provides the video pre-amplifier circuitry and CCD clock level filtering. The MIC is designed with standard four-layer FR4 printed circuit board (PCB) with surface mount and through-hole components for ease of testing and lower fabrication cost. The imager is a 3.5k by 3.5k LBNL p-channel CCD with enhanced quantum efficiency response in the UV using delta-doping technology at JPL. The recently released PCIe/104 Small-Cam CCD controller from Astronomical Research Cameras, Inc (ARC) performs readout of the detector. The PCIe/104 Small-Cam system has the same capabilities as its larger PCI brethren, but in a smaller form factor, which makes it ideally suited for sub-orbital ballistic missions. The overall control is then accomplished using a PCIe/104 computer from RTD Embedded Technologies, Inc. The design, fabrication, and testing was done at the Laboratory for Astronomical and Space Instrumentation (LASI) at Arizona State University. Integration and flight calibration are to be completed at the University of Colorado Boulder before integration into CHESS.

SCORPION II persistent surveillance system with universal gateway

NASA Astrophysics Data System (ADS)

Coster, Michael; Chambers, Jonathan; Brunck, Albert

2009-05-01

This paper addresses improvements and benefits derived from the next generation Northrop Grumman SCORPION II family of persistent surveillance and target recognition systems produced by the Xetron campus in Cincinnati, Ohio. SCORPION II reduces the size, weight, and cost of all SCORPION components in a flexible, field programmable system that is easier to conceal, backward compatible, and enables integration of over forty Unattended Ground Sensor (UGS) and camera types from a variety of manufacturers, with a modular approach to supporting multiple Line of Sight (LOS) and Beyond Line of Sight (BLOS) communications interfaces. Since 1998 Northrop Grumman has been integrating best in class sensors with its proven universal modular Gateway to provide encrypted data exfiltration to Common Operational Picture (COP) systems and remote sensor command and control. In addition to being fed to COP systems, SCORPION and SCORPION II data can be directly processed using a common sensor status graphical user interface (GUI) that allows for viewing and analysis of images and sensor data from up to seven hundred SCORPION system Gateways on single or multiple displays. This GUI enables a large amount of sensor data and imagery to be used for actionable intelligence as well as remote sensor command and control by a minimum number of analysts.

Comparison of Monte Carlo simulated and measured performance parameters of miniPET scanner

NASA Astrophysics Data System (ADS)

Kis, S. A.; Emri, M.; Opposits, G.; Bükki, T.; Valastyán, I.; Hegyesi, Gy.; Imrek, J.; Kalinka, G.; Molnár, J.; Novák, D.; Végh, J.; Kerek, A.; Trón, L.; Balkay, L.

2007-02-01

In vivo imaging of small laboratory animals is a valuable tool in the development of new drugs. For this purpose, miniPET, an easy to scale modular small animal PET camera has been developed at our institutes. The system has four modules, which makes it possible to rotate the whole detector system around the axis of the field of view. Data collection and image reconstruction are performed using a data acquisition (DAQ) module with Ethernet communication facility and a computer cluster of commercial PCs. Performance tests were carried out to determine system parameters, such as energy resolution, sensitivity and noise equivalent count rate. A modified GEANT4-based GATE Monte Carlo software package was used to simulate PET data analogous to those of the performance measurements. GATE was run on a Linux cluster of 10 processors (64 bit, Xeon with 3.0 GHz) and controlled by a SUN grid engine. The application of this special computer cluster reduced the time necessary for the simulations by an order of magnitude. The simulated energy spectra, maximum rate of true coincidences and sensitivity of the camera were in good agreement with the measured parameters.

Coincidence detection of spatially correlated photon pairs with a monolithic time-resolving detector array.

PubMed

Unternährer, Manuel; Bessire, Bänz; Gasparini, Leonardo; Stoppa, David; Stefanov, André

2016-12-12

We demonstrate coincidence measurements of spatially entangled photons by means of a multi-pixel based detection array. The sensor, originally developed for positron emission tomography applications, is a fully digital 8×16 silicon photomultiplier array allowing not only photon counting but also per-pixel time stamping of the arrived photons with an effective resolution of 265 ps. Together with a frame rate of 500 kfps, this property exceeds the capabilities of conventional charge-coupled device cameras which have become of growing interest for the detection of transversely correlated photon pairs. The sensor is used to measure a second-order correlation function for various non-collinear configurations of entangled photons generated by spontaneous parametric down-conversion. The experimental results are compared to theory.

MO-AB-206-02: Testing Gamma Cameras Based On TG177 WG Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halama, J.

2016-06-15

This education session will cover the physics and operation principles of gamma cameras and PET scanners. The first talk will focus on PET imaging. An overview of the principles of PET imaging will be provided, including positron decay physics, and the transition from 2D to 3D imaging. More recent advances in hardware and software will be discussed, such as time-of-flight imaging, and improvements in reconstruction algorithms that provide for options such as depth-of-interaction corrections. Quantitative applications of PET will be discussed, as well as the requirements for doing accurate quantitation. Relevant performance tests will also be described. Learning Objectives: Bemore » able to describe basic physics principles of PET and operation of PET scanners. Learn about recent advances in PET scanner hardware technology. Be able to describe advances in reconstruction techniques and improvements Be able to list relevant performance tests. The second talk will focus on gamma cameras. The Nuclear Medicine subcommittee has charged a task group (TG177) to develop a report on the current state of physics testing of gamma cameras, SPECT, and SPECT/CT systems. The report makes recommendations for performance tests to be done for routine quality assurance, annual physics testing, and acceptance tests, and identifies those needed satisfy the ACR accreditation program and The Joint Commission imaging standards. The report is also intended to be used as a manual with detailed instructions on how to perform tests under widely varying conditions. Learning Objectives: At the end of the presentation members of the audience will: Be familiar with the tests recommended for routine quality assurance, annual physics testing, and acceptance tests of gamma cameras for planar imaging. Be familiar with the tests recommended for routine quality assurance, annual physics testing, and acceptance tests of SPECT systems. Be familiar with the tests of a SPECT/CT system that include the CT images for SPECT reconstructions. Become knowledgeable of items to be included in annual acceptance testing reports including CT dosimetry and PACS monitor measurements. T. Turkington, GE Healthcare.« less

First Test Of A New High Resolution Positron Camera With Four Area Detectors

NASA Astrophysics Data System (ADS)

van Laethem, E.; Kuijk, M.; Deconinck, Frank; van Miert, M.; Defrise, Michel; Townsend, D.; Wensveen, M.

1989-10-01

A PET camera consisting of two pairs of parallel area detectors has been installed at the cyclotron unit of VUB. The detectors are High Density Avalanche Chambers (HIDAC) wire-chambers with a stack of 4 or 6 lead gamma-electron converters, the sensitive area being 30 by 30 cm. The detectors are mounted on a commercial gantry allowing a 180 degree rotation during acquisition, as needed for a fully 3D image reconstruction. The camera has been interfaced to a token-ring computer network consisting of 5 workstations among which the various tasks (acquisition, reconstruction, display) can be distributed. Each coincident event is coded in 48 bits and is transmitted to the computer bus via a 512 kbytes dual ported buffer memory allowing data rates of up to 50 kHz. Fully 3D image reconstruction software has been developed, and includes new reconstruction algorithms allowing a better utilization of the available projection data. Preliminary measurements and imaging of phantoms and small animals (with 18FDG) have been performed with two of the four detectors mounted on the gantry. They indicate the expected 3D isotropic spatial resolution of 3.5 mm (FWHM, line source in air) and a sensitivity of 4 cps/μCi for a centred point source in air, corresponding to typical data rates of a few kHz. This latter figure is expected to improve by a factor of 4 after coupling of the second detector pair, since the coincidence sensitivity of this second detector pair is a factor 3 higher than that of the first one.

Image enhancement in positron emission mammography

NASA Astrophysics Data System (ADS)

Slavine, Nikolai V.; Seiler, Stephen; McColl, Roderick W.; Lenkinski, Robert E.

2017-02-01

Purpose: To evaluate an efficient iterative deconvolution method (RSEMD) for improving the quantitative accuracy of previously reconstructed breast images by commercial positron emission mammography (PEM) scanner. Materials and Methods: The RSEMD method was tested on breast phantom data and clinical PEM imaging data. Data acquisition was performed on a commercial Naviscan Flex Solo II PEM camera. This method was applied to patient breast images previously reconstructed with Naviscan software (MLEM) to determine improvements in resolution, signal to noise ratio (SNR) and contrast to noise ratio (CNR.) Results: In all of the patients' breast studies the post-processed images proved to have higher resolution and lower noise as compared with images reconstructed by conventional methods. In general, the values of SNR reached a plateau at around 6 iterations with an improvement factor of about 2 for post-processed Flex Solo II PEM images. Improvements in image resolution after the application of RSEMD have also been demonstrated. Conclusions: A rapidly converging, iterative deconvolution algorithm with a novel resolution subsets-based approach RSEMD that operates on patient DICOM images has been used for quantitative improvement in breast imaging. The RSEMD method can be applied to clinical PEM images to improve image quality to diagnostically acceptable levels and will be crucial in order to facilitate diagnosis of tumor progression at the earliest stages. The RSEMD method can be considered as an extended Richardson-Lucy algorithm with multiple resolution levels (resolution subsets).

[Business administration of PET facilities: a cost analysis of three facilities utilizing delivery FDG].

PubMed

Mitsutake, Naohiro; Oku, Shinya; Fujii, Ryo; Furui, Yuji; Yasunaga, Hideo

2008-05-01

PET (positron emission tomography) has been proved to be a powerful imaging tool in clinical oncology. The number of PET facilities in Japan has remarkably increased over the last decade. Furthermore, the approval of delivery FDG in 2005 resulted in a tremendous expansion of the PET institutions without a cyclotron facility. The aim of this study was to conduct a cost analysis of PET institutions that utilized delivery FDG. Three PET facilities using delivery FDG were investigated about the costs for PET service. Fixed costs included depreciation costs for construction and medical equipments such as positron camera. Variable costs consisted of costs for medical materials including delivery FDG. The break-even point was analyzed in each of three institutions. In the three hospitals (A, B and C), the annual number of PET scan was 1,591, 1,637 and 914, while cost per scan was accounted as yen 110,262, yen 111,091, and yen 134,192, respectively. The break-even point was calculated to be 2,583, 2,679 and 2,081, respectively. PET facilities utilizing delivery FDG seemed to have difficulty in business administration. Such a situation suggests the possibility that the current supply of PET facilities might exceed actual demand for the service. The efficiency of resource allocation should be taken into consideration in the future health service researches on PET.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turkington, T.

This education session will cover the physics and operation principles of gamma cameras and PET scanners. The first talk will focus on PET imaging. An overview of the principles of PET imaging will be provided, including positron decay physics, and the transition from 2D to 3D imaging. More recent advances in hardware and software will be discussed, such as time-of-flight imaging, and improvements in reconstruction algorithms that provide for options such as depth-of-interaction corrections. Quantitative applications of PET will be discussed, as well as the requirements for doing accurate quantitation. Relevant performance tests will also be described. Learning Objectives: Bemore » able to describe basic physics principles of PET and operation of PET scanners. Learn about recent advances in PET scanner hardware technology. Be able to describe advances in reconstruction techniques and improvements Be able to list relevant performance tests. The second talk will focus on gamma cameras. The Nuclear Medicine subcommittee has charged a task group (TG177) to develop a report on the current state of physics testing of gamma cameras, SPECT, and SPECT/CT systems. The report makes recommendations for performance tests to be done for routine quality assurance, annual physics testing, and acceptance tests, and identifies those needed satisfy the ACR accreditation program and The Joint Commission imaging standards. The report is also intended to be used as a manual with detailed instructions on how to perform tests under widely varying conditions. Learning Objectives: At the end of the presentation members of the audience will: Be familiar with the tests recommended for routine quality assurance, annual physics testing, and acceptance tests of gamma cameras for planar imaging. Be familiar with the tests recommended for routine quality assurance, annual physics testing, and acceptance tests of SPECT systems. Be familiar with the tests of a SPECT/CT system that include the CT images for SPECT reconstructions. Become knowledgeable of items to be included in annual acceptance testing reports including CT dosimetry and PACS monitor measurements. T. Turkington, GE Healthcare.« less

WE-H-207A-01: Computational Evaluation of High-Resolution 18F Positron Imaging Using Radioluminescence Microscopy with Lu2O3: Eu Thin-Film Scintillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Q; Sengupta, D; Pratx, G

2016-06-15

Purpose: Radioluminescence microscopy, an emerging and powerful tool for high resolution beta imaging, has been applied to molecular imaging of cellular metabolism to understand tumor biology. A novel thin-film (10 µm thickness) scintillator made of Lu{sub 2}O{sub 3}: Eu has been developed to enhance the system performance. However the advances of radioluminescence imaging with Lu{sub 2}O{sub 3}scintillator compared with that using conventional scintillator have not been explored theoretically to date. To validate the advantages of the thin-film scintillator, this study uses a novel computational simulation framework to evaluate the performance of radioluminescence microscopy using both conventional and thin-film scintillators. Methods:more » Numerical models for different stages of positron imaging are established. Positron from {sup 18}F passing through the scintillator and its neighbor structures are modeled by Monte-Carlo simulation using Geant4. The propagation and focus of photons by the microscope are modeled by convolution with a depth-varying point spread function generated by the Gibson-Lanni model. Photons focused on the detector plane are then captured and converted into electronic signals by an electron multiplication (EM) CCD camera, which is described by a photosensor model considering various noises and charge amplification. Results: The performance metrics of radioluminescence imaging with a thin-film Lu{sub 2}O{sub 3} and conventional CdWO{sub 4} scintillator are compared, including spatial resolution, sensitivity, positron track area and intensity. The spatial resolution of Lu{sub 2}O{sub 3} system can achieve 10 µm maximally, a 12 µm enhancement from that obtained from CdWO{sub 4} system. Meanwhile, the system with Lu{sub 2}O{sub 3} scintillator can provide a higher mean sensitivity: 40% compared with that (21.5%) obtained from CdWO{sub 4} system. Moreover, the simulation results are in good agreement with previous experimental measurements. Conclusion: This study provides a new theoretical understanding of our imaging system and has the potential to promote the development of radioluminescence microscopy for more reliable and robust application on the functional imaging of delicate biological structures. The authors acknowledge funding from NIH grant R01CA186275 and SBIR grant 1R43GM110888-01.« less

Noninvasive imaging of cationic lipid-mediated delivery of optical and PET reporter genes in living mice.

PubMed

Iyer, Meera; Berenji, Manijeh; Templeton, Nancy S; Gambhir, Sanjiv S

2002-10-01

Gene therapy involves the safe and effective delivery of one or more genes of interest to target cells in vivo. The advantages of using nonviral delivery systems include ease of preparation, low toxicity, and weak immunogenicity. Nonviral delivery methods, when combined with a noninvasive, clinically applicable imaging assay, will greatly aid in the optimization of gene therapy approaches for cancer. We demonstrate cationic lipid-mediated noninvasive monitoring of reporter gene expression of firefly (Photinus pyralis) luciferase (fl) and a mutant herpes simplex virus type I thymidine kinase (HSV1-sr39tk, tk) in living mice using a cooled charge coupled device (CCD) camera and positron emission tomography (PET), respectively. We observe a high level of fl and tk reporter gene expression predominantly in the lungs after a single injection of the extruded DOTAP:cholesterol DNA liposome complexes by way of the tail vein, seen to be time- and dose-dependent. We observe a good correlation between the in vivo bioluminescent signal and the ex vivo firefly luciferase enzyme (FL) activity in different organs. We further demonstrate the feasibility of noninvasively imaging both optical and PET reporter gene expression in the same animal using the CCD camera and microPET, respectively.

An image engineering system for the inspection of transparent construction materials

NASA Astrophysics Data System (ADS)

Hinz, S.; Stephani, M.; Schiemann, L.; Zeller, K.

This article presents a modular photogrammetric recording and image analysis system for inspecting the material characteristics of transparent foils, in particular Ethylen-TetraFluorEthylen-Copolymer (ETFE) foils. The foils are put under increasing air pressure and are observed by a stereo camera system. Determining the time-variable 3D shape of transparent material imposes a number of challenges: especially the automatic point transfer between stereo images and, in temporal domain, from one image pair to the next. We developed an automatic approach that accommodates for these particular circumstances and allows reconstruction of the 3D shape for each epoch as well as determining 3D translation vectors between epochs by feature tracking. Examples including numerical results and accuracy measures prove the applicability of the system.

Parallel robot for micro assembly with integrated innovative optical 3D-sensor

NASA Astrophysics Data System (ADS)

Hesselbach, Juergen; Ispas, Diana; Pokar, Gero; Soetebier, Sven; Tutsch, Rainer

2002-10-01

Recent advances in the fields of MEMS and MOEMS often require precise assembly of very small parts with an accuracy of a few microns. In order to meet this demand, a new approach using a robot based on parallel mechanisms in combination with a novel 3D-vision system has been chosen. The planar parallel robot structure with 2 DOF provides a high resolution in the XY-plane. It carries two additional serial axes for linear and rotational movement in/about z direction. In order to achieve high precision as well as good dynamic capabilities, the drive concept for the parallel (main) axes incorporates air bearings in combination with a linear electric servo motors. High accuracy position feedback is provided by optical encoders with a resolution of 0.1 μm. To allow for visualization and visual control of assembly processes, a camera module fits into the hollow tool head. It consists of a miniature CCD camera and a light source. In addition a modular gripper support is integrated into the tool head. To increase the accuracy a control loop based on an optoelectronic sensor will be implemented. As a result of an in-depth analysis of different approaches a photogrammetric system using one single camera and special beam-splitting optics was chosen. A pattern of elliptical marks is applied to the surfaces of workpiece and gripper. Using a model-based recognition algorithm the image processing software identifies the gripper and the workpiece and determines their relative position. A deviation vector is calculated and fed into the robot control to guide the gripper.

Multispectral imaging of the ocular fundus using light emitting diode illumination

NASA Astrophysics Data System (ADS)

Everdell, N. L.; Styles, I. B.; Calcagni, A.; Gibson, J.; Hebden, J.; Claridge, E.

2010-09-01

We present an imaging system based on light emitting diode (LED) illumination that produces multispectral optical images of the human ocular fundus. It uses a conventional fundus camera equipped with a high power LED light source and a highly sensitive electron-multiplying charge coupled device camera. It is able to take pictures at a series of wavelengths in rapid succession at short exposure times, thereby eliminating the image shift introduced by natural eye movements (saccades). In contrast with snapshot systems the images retain full spatial resolution. The system is not suitable for applications where the full spectral resolution is required as it uses discrete wavebands for illumination. This is not a problem in retinal imaging where the use of selected wavelengths is common. The modular nature of the light source allows new wavelengths to be introduced easily and at low cost. The use of wavelength-specific LEDs as a source is preferable to white light illumination and subsequent filtering of the remitted light as it minimizes the total light exposure of the subject. The system is controlled via a graphical user interface that enables flexible control of intensity, duration, and sequencing of sources in synchrony with the camera. Our initial experiments indicate that the system can acquire multispectral image sequences of the human retina at exposure times of 0.05 s in the range of 500-620 nm with mean signal to noise ratio of 17 dB (min 11, std 4.5), making it suitable for quantitative analysis with application to the diagnosis and screening of eye diseases such as diabetic retinopathy and age-related macular degeneration.

Multispectral imaging of the ocular fundus using light emitting diode illumination.

PubMed

Everdell, N L; Styles, I B; Calcagni, A; Gibson, J; Hebden, J; Claridge, E

2010-09-01

We present an imaging system based on light emitting diode (LED) illumination that produces multispectral optical images of the human ocular fundus. It uses a conventional fundus camera equipped with a high power LED light source and a highly sensitive electron-multiplying charge coupled device camera. It is able to take pictures at a series of wavelengths in rapid succession at short exposure times, thereby eliminating the image shift introduced by natural eye movements (saccades). In contrast with snapshot systems the images retain full spatial resolution. The system is not suitable for applications where the full spectral resolution is required as it uses discrete wavebands for illumination. This is not a problem in retinal imaging where the use of selected wavelengths is common. The modular nature of the light source allows new wavelengths to be introduced easily and at low cost. The use of wavelength-specific LEDs as a source is preferable to white light illumination and subsequent filtering of the remitted light as it minimizes the total light exposure of the subject. The system is controlled via a graphical user interface that enables flexible control of intensity, duration, and sequencing of sources in synchrony with the camera. Our initial experiments indicate that the system can acquire multispectral image sequences of the human retina at exposure times of 0.05 s in the range of 500-620 nm with mean signal to noise ratio of 17 dB (min 11, std 4.5), making it suitable for quantitative analysis with application to the diagnosis and screening of eye diseases such as diabetic retinopathy and age-related macular degeneration.

A General Quantum Mechanical Method to Predict Positron Spectroscopy

DTIC Science & Technology

2007-06-01

7 2.1 Positron Annihilation Spectroscopy . . . . . . . . . . . . . 7 2.1.1 Positron Transport and Annihilation in Condensed Matter...8 2.1.2 Traditional Positron Annihilation Spectroscopy . . 10 2.1.3 Vibrational Feshbach Resonances of Positrons with... positron annihilation lifetime spectroscopy system . . . 63 11. Tungsten positron lifetime spectrum . . . . . . . . . . . . . . . . . . 66 12. K2B12H12

Positron transport in solids and the interaction of positrons with surfaces

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kong, Yuan.

1991-01-01

In studying positron transport in solids, a two-stream model is proposed to account for the epithermal positrons. Thus positron implantation, thermalization, and diffusion processes are completely modeled. Experimentally, positron mobility in thermally grown SiO[sub 2] is measured in a sandwiched structure by using the Doppler broadening technique. Positron drift motion and the electric field configuration in a Si surface buried under overlayers are measured with the positron annihilation [gamma]-ray centroid shift technique. These studies are not only important in measuring positron transport and other properties in complicated systems, they are also of practical significance for material characterizations. In studying positronmore » interactions with surfaces, a multiple-encounter picture is proposed of thermal positrons participating in the surface escape processes. Positron trapping into the surface image potential is also studied, considering the long-range nature of the image potential. Experimentally, the positron annihilation induced Auger electron spectroscopy (PAES) is used to study an ionic insulator surface KCl(100).« less

A versatile indirect detector design for hard X-ray microimaging

NASA Astrophysics Data System (ADS)

Douissard, P.-A.; Cecilia, A.; Rochet, X.; Chapel, X.; Martin, T.; van de Kamp, T.; Helfen, L.; Baumbach, T.; Luquot, L.; Xiao, X.; Meinhardt, J.; Rack, A.

2012-09-01

Indirect X-ray detectors are of outstanding importance for high resolution imaging, especially at synchrotron light sources: while consisting mostly of components which are widely commercially available, they allow for a broad range of applications in terms of the X-ray energy employed, radiation dose to the detector, data acquisition rate and spatial resolving power. Frequently, an indirect detector consists of a thin-film single crystal scintillator and a high-resolution visible light microscope as well as a camera. In this article, a novel modular-based indirect design is introduced, which offers several advantages: it can be adapted for different cameras, i.e. different sensor sizes, and can be trimmed to work either with (quasi-)monochromatic illumination and the correspondingly lower absorbed dose or with intense white beam irradiation. In addition, it allows for a motorized quick exchange between different magnifications / spatial resolutions. Developed within the European project SCINTAX, it is now commercially available. The characteristics of the detector in its different configurations (i.e. for low dose or for high dose irradiation) as measured within the SCINTAX project will be outlined. Together with selected applications from materials research, non-destructive evaluation and life sciences they underline the potential of this design to make high resolution X-ray imaging widely available.

High-performance electronics for time-of-flight PET systems

NASA Astrophysics Data System (ADS)

Choong, W.-S.; Peng, Q.; Vu, C. Q.; Turko, B. T.; Moses, W. W.

2013-01-01

We have designed and built a high-performance readout electronics system for time-of-flight positron emission tomography (TOF PET) cameras. The electronics architecture is based on the electronics for a commercial whole-body PET camera (Siemens/CPS Cardinal electronics), modified to improve the timing performance. The fundamental contributions in the electronics that can limit the timing resolution include the constant fraction discriminator (CFD), which converts the analog electrical signal from the photo-detector to a digital signal whose leading edge is time-correlated with the input signal, and the time-to-digital converter (TDC), which provides a time stamp for the CFD output. Coincident events are identified by digitally comparing the values of the time stamps. In the Cardinal electronics, the front-end processing electronics are performed by an Analog subsection board, which has two application-specific integrated circuits (ASICs), each servicing a PET block detector module. The ASIC has a built-in CFD and TDC. We found that a significant degradation in the timing resolution comes from the ASIC's CFD and TDC. Therefore, we have designed and built an improved Analog subsection board that replaces the ASIC's CFD and TDC with a high-performance CFD (made with discrete components) and TDC (using the CERN high-performance TDC ASIC). The improved Analog subsection board is used in a custom single-ring LSO-based TOF PET camera. The electronics system achieves a timing resolution of 60 ps FWHM. Prototype TOF detector modules are read out with the electronics system and give coincidence timing resolutions of 259 ps FWHM and 156 ps FWHM for detector modules coupled to LSO and LaBr3 crystals respectively.

High-performance electronics for time-of-flight PET systems.

PubMed

Choong, W-S; Peng, Q; Vu, C Q; Turko, B T; Moses, W W

2013-01-01

We have designed and built a high-performance readout electronics system for time-of-flight positron emission tomography (TOF PET) cameras. The electronics architecture is based on the electronics for a commercial whole-body PET camera (Siemens/CPS Cardinal electronics), modified to improve the timing performance. The fundamental contributions in the electronics that can limit the timing resolution include the constant fraction discriminator (CFD), which converts the analog electrical signal from the photo-detector to a digital signal whose leading edge is time-correlated with the input signal, and the time-to-digital converter (TDC), which provides a time stamp for the CFD output. Coincident events are identified by digitally comparing the values of the time stamps. In the Cardinal electronics, the front-end processing electronics are performed by an Analog subsection board, which has two application-specific integrated circuits (ASICs), each servicing a PET block detector module. The ASIC has a built-in CFD and TDC. We found that a significant degradation in the timing resolution comes from the ASIC's CFD and TDC. Therefore, we have designed and built an improved Analog subsection board that replaces the ASIC's CFD and TDC with a high-performance CFD (made with discrete components) and TDC (using the CERN high-performance TDC ASIC). The improved Analog subsection board is used in a custom single-ring LSO-based TOF PET camera. The electronics system achieves a timing resolution of 60 ps FWHM. Prototype TOF detector modules are read out with the electronics system and give coincidence timing resolutions of 259 ps FWHM and 156 ps FWHM for detector modules coupled to LSO and LaBr 3 crystals respectively.

Method for photon activation positron annihilation analysis

DOEpatents

Akers, Douglas W.

2006-06-06

A non-destructive testing method comprises providing a specimen having at least one positron emitter therein; determining a threshold energy for activating the positron emitter; and determining whether a half-life of the positron emitter is less than a selected half-life. If the half-life of the positron emitter is greater than or equal to the selected half-life, then activating the positron emitter by bombarding the specimen with photons having energies greater than the threshold energy and detecting gamma rays produced by annihilation of positrons in the specimen. If the half-life of the positron emitter is less then the selected half-life, then alternately activating the positron emitter by bombarding the specimen with photons having energies greater then the threshold energy and detecting gamma rays produced by positron annihilation within the specimen.

Development of TlBr detectors for PET imaging.

PubMed

Ariño-Estrada, Gerard; Du, Junwei; Kim, Hadong; Cirignano, Leonard J; Shah, Kanai S; Cherry, Simon R; Mitchell, Gregory S

2018-05-04

Thallium bromide (TlBr) is a promising semiconductor detector material for positron emission tomography (PET) because it can offer very good energy resolution and 3-D segmentation capabilities, and it also provides detection efficiency surpassing that of commonly used scintillators. Energy, timing, and spatial resolution were measured for thin (<1 mm) TlBr detectors. The energy and timing resolution were measured simultaneously for the same planar 0.87 mm-thick TlBr device. An energy resolution of (6.41.3)% at 511 keV was achieved at -400 V bias voltage and at room temperature. A timing resolution of (27.84.1) ns FWHM was achieved for the same operating conditions when appropriate energy gating was applied. The intrinsic spatial resolution was measured to be 0.9 mm FWHM for a TlBr detector with metallic strip contacts of 0.5 mm pitch. As material properties improve, higher bias voltage should improve timing performance. A stack of thin detectors with finely segmented readout can create a modular detector with excellent energy and spatial resolution for PET applications. . © 2018 Institute of Physics and Engineering in Medicine.

1985 Nuclear Science Symposium, 32nd, and 1985 Symposium on Nuclear Power Systems, 17th, San Francisco, CA, October 23-25, 1985, Proceedings

NASA Technical Reports Server (NTRS)

1986-01-01

The present conference ranges over topics in high energy physics instrumentation, detectors, nuclear medical applications, health physics and environmental monitoring, reactor instrumentation, nuclear spacecraft instrumentation, the 'Fastbus' data acquisition system, circuits and systems for nuclear research facilities, and the development status of nuclear power systems. Specific attention is given to CCD high precision detectors, a drift chamber preamplifier, a Cerenkov ring imaging detector, novel scintillation glasses and scintillating fibers, a modular multidrift vertex detector, radial wire drift chambers, liquid argon polarimeters, a multianode photomultiplier, the reliability of planar silicon detectors, the design and manufacture of wedge and strip anodes, ultrafast triode photodetectors, photomultiplier tubes, a barium fluoride plastic scintillator, a fine grained neutron hodoscope, the stability of low leakage silicon photodiodes for crystal calorimeters, and X-ray proportional counters. Also considered are positron emission tomography, single photon emission computed tomography, nuclear magnetic resonance imaging, Geiger-Muller detectors, nuclear plant safeguards, a 32-bit Fastbus computer, an advanced light water reactor, and nuclear plant maintenance.

Multiscale modeling of metabolism, flows, and exchanges in heterogeneous organs

PubMed Central

Bassingthwaighte, James B.; Raymond, Gary M.; Butterworth, Erik; Alessio, Adam; Caldwell, James H.

2010-01-01

Large-scale models accounting for the processes supporting metabolism and function in an organ or tissue with a marked heterogeneity of flows and metabolic rates are computationally complex and tedious to compute. Their use in the analysis of data from positron emission tomography (PET) and magnetic resonance imaging (MRI) requires model reduction since the data are composed of concentration–time curves from hundreds of regions of interest (ROI) within the organ. Within each ROI, one must account for blood flow, intracapillary gradients in concentrations, transmembrane transport, and intracellular reactions. Using modular design, we configured a whole organ model, GENTEX, to allow adaptive usage for multiple reacting molecular species while omitting computation of unused components. The temporal and spatial resolution and the number of species are adaptable and the numerical accuracy and computational speed is adjustable during optimization runs, which increases accuracy and spatial resolution as convergence approaches. An application to the interpretation of PET image sequences after intravenous injection of 13NH3 provides functional image maps of regional myocardial blood flows. PMID:20201893

The structure, logic of operation and distinctive features of the system of triggers and counting signals formation for gamma-telescope GAMMA-400

NASA Astrophysics Data System (ADS)

Topchiev, N. P.; Galper, A. M.; Arkhangelskiy, A. I.; Arkhangelskaja, I. V.; Kheymits, M. D.; Suchkov, S. I.; Yurkin, Y. T.

2017-01-01

Scientific project GAMMA-400 (Gamma Astronomical Multifunctional Modular Apparatus) relates to the new generation of space observatories intended to perform an indirect search for signatures of dark matter in the cosmic-ray fluxes, measurements of characteristics of diffuse gamma-ray emission and gamma-rays from the Sun during periods of solar activity, gamma-ray bursts, extended and point gamma-ray sources, electron/positron and cosmic-ray nuclei fluxes up to TeV energy region by means of the GAMMA-400 gamma-ray telescope represents the core of the scientific complex. The system of triggers and counting signals formation of the GAMMA-400 gamma-ray telescope constitutes the pipelined processor structure which collects data from the gamma-ray telescope subsystems and produces summary information used in forming the trigger decision for each event. The system design is based on the use of state-of-the-art reconfigurable logic devices and fast data links. The basic structure, logic of operation and distinctive features of the system are presented.

A philosophy for CNS radiotracer design.

PubMed

Van de Bittner, Genevieve C; Ricq, Emily L; Hooker, Jacob M

2014-10-21

Decades after its discovery, positron emission tomography (PET) remains the premier tool for imaging neurochemistry in living humans. Technological improvements in radiolabeling methods, camera design, and image analysis have kept PET in the forefront. In addition, the use of PET imaging has expanded because researchers have developed new radiotracers that visualize receptors, transporters, enzymes, and other molecular targets within the human brain. However, of the thousands of proteins in the central nervous system (CNS), researchers have successfully imaged fewer than 40 human proteins. To address the critical need for new radiotracers, this Account expounds on the decisions, strategies, and pitfalls of CNS radiotracer development based on our current experience in this area. We discuss the five key components of radiotracer development for human imaging: choosing a biomedical question, selection of a biological target, design of the radiotracer chemical structure, evaluation of candidate radiotracers, and analysis of preclinical imaging. It is particularly important to analyze the market of scientists or companies who might use a new radiotracer and carefully select a relevant biomedical question(s) for that audience. In the selection of a specific biological target, we emphasize how target localization and identity can constrain this process and discuss the optimal target density and affinity ratios needed for binding-based radiotracers. In addition, we discuss various PET test-retest variability requirements for monitoring changes in density, occupancy, or functionality for new radiotracers. In the synthesis of new radiotracer structures, high-throughput, modular syntheses have proved valuable, and these processes provide compounds with sites for late-stage radioisotope installation. As a result, researchers can manage the time constraints associated with the limited half-lives of isotopes. In order to evaluate brain uptake, a number of methods are available to predict bioavailability, blood-brain barrier (BBB) permeability, and the associated issues of nonspecific binding and metabolic stability. To evaluate the synthesized chemical library, researchers need to consider high-throughput affinity assays, the analysis of specific binding, and the importance of fast binding kinetics. Finally, we describe how we initially assess preclinical radiotracer imaging, using brain uptake, specific binding, and preliminary kinetic analysis to identify promising radiotracers that may be useful for human brain imaging. Although we discuss these five design components separately and linearly in this Account, in practice we develop new PET-based radiotracers using these design components nonlinearly and iteratively to develop new compounds in the most efficient way possible.

Two-component density functional theory calculations of positron lifetimes for small vacancy clusters in silicon

NASA Astrophysics Data System (ADS)

Makhov, D. V.; Lewis, Laurent J.

2005-05-01

The positron lifetimes for various vacancy clusters in silicon are calculated within the framework of the two-component electron-positron density functional theory. The effect of the trapped positron on the electron density and on the relaxation of the structure is investigated. Our calculations show that, contrary to the usual assumption, the positron-induced forces do not compensate in general for electronic inward forces. Thus, geometry optimization is required in order to determine positron lifetime accurately. For the monovacancy and the divacancy, the results of our calculations are in good agreement with the experimental positron lifetimes, suggesting that this approach gives good estimates of positron lifetimes for larger vacancy clusters, required for their correct identification with positron annihilation spectroscopy. As an application, our calculations show that fourfold trivacancies and symmetric fourfold tetravacancies have positron lifetimes similar to monovacancies and divacancies, respectively, and can thus be confused in the interpretation of positron annihilation experiments.

Joint project of the international network of agencies for health technology assessment--Part 1: Survey results on diffusion, assessment, and clinical use of positron emission tomography.

PubMed

Hastings, John; Adams, Elizabeth J

2006-01-01

The International Network of Agencies for Health Technology Assessment (INAHTA) has been tracking activities associated with the clinical use of positron emission tomography (PET) in its members' healthcare systems since 1997 and published its first Joint Project report on PET in 1999. Part 1 of this Joint Project report presents survey results on diffusion, assessment activities, and policy for clinical use related to PET among INAHTA members since 1999. INAHTA members were surveyed in 2003-2004. Twenty-seven INAHTA agencies (69 percent response rate) from nineteen countries responded to the survey. Dedicated PET systems are the most universally installed systems to date. Mobile scanners and modified gamma cameras are used occasionally as lower cost alternatives, and interest in PET-computed tomography hybrid models is rising despite limited assessment of impact on service planning. PET was used and assessed most commonly for managing patients with cancer. All respondents reported having some form of public funding for clinical PET frequently linked to data collection for the purpose of gathering evidence to refine clinical use and guide resource allocation toward indications that maximize clinical and cost-effectiveness. The use of HTA within a continuous quality improvement framework can help optimize scarce resources for evaluation and use of high cost diagnostic technologies such as PET, particularly where potential clinical or cost-effectiveness is considerable but conclusive evidence is lacking.

Positron Emission Tomography - Computed Tomography (PET/CT)

MedlinePlus

... A-Z Positron Emission Tomography - Computed Tomography (PET/CT) Positron emission tomography (PET) uses small amounts of ... What is Positron Emission Tomography – Computed Tomography (PET/CT) Scanning? Positron emission tomography, also called PET imaging ...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Virador, Patrick R.G.

The author performs image reconstruction for a novel Positron Emission Tomography camera that is optimized for breast cancer imaging. This work addresses for the first time, the problem of fully-3D, tomographic reconstruction using a septa-less, stationary, (i.e. no rotation or linear motion), and rectangular camera whose Field of View (FOV) encompasses the entire volume enclosed by detector modules capable of measuring Depth of Interaction (DOI) information. The camera is rectangular in shape in order to accommodate breasts of varying sizes while allowing for soft compression of the breast during the scan. This non-standard geometry of the camera exacerbates two problems:more » (a) radial elongation due to crystal penetration and (b) reconstructing images from irregularly sampled data. Packing considerations also give rise to regions in projection space that are not sampled which lead to missing information. The author presents new Fourier Methods based image reconstruction algorithms that incorporate DOI information and accommodate the irregular sampling of the camera in a consistent manner by defining lines of responses (LORs) between the measured interaction points instead of rebinning the events into predefined crystal face LORs which is the only other method to handle DOI information proposed thus far. The new procedures maximize the use of the increased sampling provided by the DOI while minimizing interpolation in the data. The new algorithms use fixed-width evenly spaced radial bins in order to take advantage of the speed of the Fast Fourier Transform (FFT), which necessitates the use of irregular angular sampling in order to minimize the number of unnormalizable Zero-Efficiency Bins (ZEBs). In order to address the persisting ZEBs and the issue of missing information originating from packing considerations, the algorithms (a) perform nearest neighbor smoothing in 2D in the radial bins (b) employ a semi-iterative procedure in order to estimate the unsampled data and (c) mash the in plane projections, i.e. 2D data, with the projection data from the first oblique angles, which are then used to reconstruct the preliminary image in the 3D Reprojection Projection algorithm. The author presents reconstructed images of point sources and extended sources in both 2D and 3D. The images show that the camera is anticipated to eliminate radial elongation and produce artifact free and essentially spatially isotropic images throughout the entire FOV. It has a resolution of 1.50 ± 0.75 mm FWHM near the center, 2.25 ±0.75 mm FWHM in the bulk of the FOV, and 3.00 ± 0.75 mm FWHM near the edge and corners of the FOV.« less

GEECS (Generalized Equipment and Experiment Control System)

DOE Office of Scientific and Technical Information (OSTI.GOV)

GONSALVES, ANTHONY; DESHMUKH, AALHAD

2017-01-12

GEECS (Generalized Equipment and Experiment Control System) monitors and controls equipment distributed across a network, performs experiments by scanning input variables, and collects and stores various types of data synchronously from devices. Examples of devices include cameras, motors and pressure gauges. GEEKS is based upon LabView graphical object oriented programming (GOOP), allowing for a modular and scalable framework. Data is published for subscription of an arbitrary number of variables over TCP. A secondary framework allows easy development of graphical user interfaces for a combined control of any available devices on the control system without the need of programming knowledge. Thismore » allows for rapid integration of GEECS into a wide variety of systems. A database interface provides for devise and process configuration while allowing the user to save large quantities of data to local or network drives.« less

Positron Beam Characteristics at NEPOMUC Upgrade

NASA Astrophysics Data System (ADS)

Hugenschmidt, C.; Ceeh, H.; Gigl, T.; Lippert, F.; Piochacz, C.; Reiner, M.; Schreckenbach, K.; Vohburger, S.; Weber, J.; Zimnik, S.

2014-04-01

In 2012, the new neutron induced positron source NEPOMUC upgrade was put into operation at FRMII. Major changes have been made to the source which consists of a neutron-γ-converter out of Cd and a Pt foil structure for electron positron pair production and positron moderation. The new design leads to an improvement of both intensity and brightness of the mono-energetic positron beam. In addition, the application of highly enriched 113Cd as neutron-γ-converter extends the lifetime of the positron source to 25 years. A new switching and remoderation device has been installed in order to allow toggling from the high-intensity primary beam to a brightness enhanced remoderated positron beam. At present, an intensity of more than 109 moderated positrons per second is achieved at NEPOMUC upgrade. The main characteristics are presented which comprise positron yield and beam profile of both the primary and the remoderated positron beam.

Development of an Electron-Positron Source for Positron Annihilation Lifetime Spectroscopy

DTIC Science & Technology

2009-12-19

REPORT Development of an electron- positron source for positron annihilation lifetime spectroscopy : FINAL REPORT 14. ABSTRACT 16. SECURITY...to generate radiation, to accelerate particles, and to produce electrons and positrons from vacuum. From applications using existing high-repetition...theoretical directions. This report reviews work directed toward the application of positron generation from laser interaction with matter 1. REPORT DATE

Design of a portable optical emission tomography system for microwave induced compact plasma for visible to near-infrared emission lines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rathore, Kavita, E-mail: kavira@iitk.ac.in, E-mail: pmunshi@iitk.ac.in, E-mail: sudeepb@iitk.ac.in; Munshi, Prabhat, E-mail: kavira@iitk.ac.in, E-mail: pmunshi@iitk.ac.in, E-mail: sudeepb@iitk.ac.in; Bhattacharjee, Sudeep, E-mail: kavira@iitk.ac.in, E-mail: pmunshi@iitk.ac.in, E-mail: sudeepb@iitk.ac.in

A new non-invasive diagnostic system is developed for Microwave Induced Plasma (MIP) to reconstruct tomographic images of a 2D emission profile. A compact MIP system has wide application in industry as well as research application such as thrusters for space propulsion, high current ion beams, and creation of negative ions for heating of fusion plasma. Emission profile depends on two crucial parameters, namely, the electron temperature and density (over the entire spatial extent) of the plasma system. Emission tomography provides basic understanding of plasmas and it is very useful to monitor internal structure of plasma phenomena without disturbing its actualmore » processes. This paper presents development of a compact, modular, and versatile Optical Emission Tomography (OET) tool for a cylindrical, magnetically confined MIP system. It has eight slit-hole cameras and each consisting of a complementary metal–oxide–semiconductor linear image sensor for light detection. The optical noise is reduced by using aspheric lens and interference band-pass filters in each camera. The entire cylindrical plasma can be scanned with automated sliding ring mechanism arranged in fan-beam data collection geometry. The design of the camera includes a unique possibility to incorporate different filters to get the particular wavelength light from the plasma. This OET system includes selected band-pass filters for particular argon emission 750 nm, 772 nm, and 811 nm lines and hydrogen emission H{sub α} (656 nm) and H{sub β} (486 nm) lines. Convolution back projection algorithm is used to obtain the tomographic images of plasma emission line. The paper mainly focuses on (a) design of OET system in detail and (b) study of emission profile for 750 nm argon emission lines to validate the system design.« less

Theory for the Emergence of Modularity in Complex Systems

NASA Astrophysics Data System (ADS)

Deem, Michael; Park, Jeong-Man

2013-03-01

Biological systems are modular, and this modularity evolves over time and in different environments. A number of observations have been made of increased modularity in biological systems under increased environmental pressure. We here develop a theory for the dynamics of modularity in these systems. We find a principle of least action for the evolved modularity at long times. In addition, we find a fluctuation dissipation relation for the rate of change of modularity at short times. We discuss a number of biological and social systems that can be understood with this framework. The modularity of the protein-protein interaction network increases when yeast are exposed to heat shock, and the modularity of the protein-protein networks in both yeast and E. coli appears to have increased over evolutionary time. Food webs in low-energy, stressful environments are more modular than those in plentiful environments, arid ecologies are more modular during droughts, and foraging of sea otters is more modular when food is limiting. The modularity of social networks changes over time: stock brokers instant messaging networks are more modular under stressful market conditions, criminal networks are more modular under increased police pressure, and world trade network modularity has decreased

Thermal regulation of tightly packed solid-state photodetectors in a 1 mm3 resolution clinical PET system

PubMed Central

Vandenbroucke, A.; Innes, D.; Lau, F. W. Y.; Hsu, D. F. C.; Reynolds, P. D.; Levin, Craig S.

2015-01-01

Purpose: Silicon photodetectors are of significant interest for use in positron emission tomography (PET) systems due to their compact size, insensitivity to magnetic fields, and high quantum efficiency. However, one of their main disadvantages is fluctuations in temperature cause strong shifts in gain of the devices. PET system designs with high photodetector density suffer both increased thermal density and constrained options for thermally regulating the devices. This paper proposes a method of thermally regulating densely packed silicon photodetectors in the context of a 1 mm3 resolution, high-sensitivity PET camera dedicated to breast imaging. Methods: The PET camera under construction consists of 2304 units, each containing two 8 × 8 arrays of 1 mm3 LYSO crystals coupled to two position sensitive avalanche photodiodes (PSAPD). A subsection of the proposed camera with 512 PSAPDs has been constructed. The proposed thermal regulation design uses water-cooled heat sinks, thermoelectric elements, and thermistors to measure and regulate the temperature of the PSAPDs in a novel manner. Active cooling elements, placed at the edge of the detector stack due to limited access, are controlled based on collective leakage current and temperature measurements in order to keep all the PSAPDs at a consistent temperature. This thermal regulation design is characterized for the temperature profile across the camera and for the time required for cooling changes to propagate across the camera. These properties guide the implementation of a software-based, cascaded proportional-integral-derivative control loop that controls the current through the Peltier elements by monitoring thermistor temperature and leakage current. The stability of leakage current, temperature within the system using this control loop is tested over a period of 14 h. The energy resolution is then measured over a period of 8.66 h. Finally, the consistency of PSAPD gain between independent operations of the camera over 10 days is tested. Results: The PET camera maintains a temperature of 18.00 ± 0.05 °C over the course of 12 h while the ambient temperature varied 0.61 °C, from 22.83 to 23.44 °C. The 511 keV photopeak energy resolution over a period of 8.66 h is measured to be 11.3% FWHM with a maximum photopeak fluctuation of 4 keV. Between measurements of PSAPD gain separated by at least 2 day, the maximum photopeak shift was 6 keV. Conclusions: The proposed thermal regulation scheme for tightly packed silicon photodetectors provides for stable operation of the constructed subsection of a PET camera over long durations of time. The energy resolution of the system is not degraded despite shifts in ambient temperature and photodetector heat generation. The thermal regulation scheme also provides a consistent operating environment between separate runs of the camera over different days. Inter-run consistency allows for reuse of system calibration parameters from study to study, reducing the time required to calibrate the system and hence to obtain a reconstructed image. PMID:25563270

Thermal regulation of tightly packed solid-state photodetectors in a 1 mm{sup 3} resolution clinical PET system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Freese, D. L.; Vandenbroucke, A.; Innes, D.

2015-01-15

Purpose: Silicon photodetectors are of significant interest for use in positron emission tomography (PET) systems due to their compact size, insensitivity to magnetic fields, and high quantum efficiency. However, one of their main disadvantages is fluctuations in temperature cause strong shifts in gain of the devices. PET system designs with high photodetector density suffer both increased thermal density and constrained options for thermally regulating the devices. This paper proposes a method of thermally regulating densely packed silicon photodetectors in the context of a 1 mm{sup 3} resolution, high-sensitivity PET camera dedicated to breast imaging. Methods: The PET camera under constructionmore » consists of 2304 units, each containing two 8 × 8 arrays of 1 mm{sup 3} LYSO crystals coupled to two position sensitive avalanche photodiodes (PSAPD). A subsection of the proposed camera with 512 PSAPDs has been constructed. The proposed thermal regulation design uses water-cooled heat sinks, thermoelectric elements, and thermistors to measure and regulate the temperature of the PSAPDs in a novel manner. Active cooling elements, placed at the edge of the detector stack due to limited access, are controlled based on collective leakage current and temperature measurements in order to keep all the PSAPDs at a consistent temperature. This thermal regulation design is characterized for the temperature profile across the camera and for the time required for cooling changes to propagate across the camera. These properties guide the implementation of a software-based, cascaded proportional-integral-derivative control loop that controls the current through the Peltier elements by monitoring thermistor temperature and leakage current. The stability of leakage current, temperature within the system using this control loop is tested over a period of 14 h. The energy resolution is then measured over a period of 8.66 h. Finally, the consistency of PSAPD gain between independent operations of the camera over 10 days is tested. Results: The PET camera maintains a temperature of 18.00 ± 0.05 °C over the course of 12 h while the ambient temperature varied 0.61 °C, from 22.83 to 23.44 °C. The 511 keV photopeak energy resolution over a period of 8.66 h is measured to be 11.3% FWHM with a maximum photopeak fluctuation of 4 keV. Between measurements of PSAPD gain separated by at least 2 day, the maximum photopeak shift was 6 keV. Conclusions: The proposed thermal regulation scheme for tightly packed silicon photodetectors provides for stable operation of the constructed subsection of a PET camera over long durations of time. The energy resolution of the system is not degraded despite shifts in ambient temperature and photodetector heat generation. The thermal regulation scheme also provides a consistent operating environment between separate runs of the camera over different days. Inter-run consistency allows for reuse of system calibration parameters from study to study, reducing the time required to calibrate the system and hence to obtain a reconstructed image.« less

Unified Digital Image Display And Processing System

NASA Astrophysics Data System (ADS)

Horii, Steven C.; Maguire, Gerald Q.; Noz, Marilyn E.; Schimpf, James H.

1981-11-01

Our institution like many others, is faced with a proliferation of medical imaging techniques. Many of these methods give rise to digital images (e.g. digital radiography, computerized tomography (CT) , nuclear medicine and ultrasound). We feel that a unified, digital system approach to image management (storage, transmission and retrieval), image processing and image display will help in integrating these new modalities into the present diagnostic radiology operations. Future techniques are likely to employ digital images, so such a system could readily be expanded to include other image sources. We presently have the core of such a system. We can both view and process digital nuclear medicine (conventional gamma camera) images, positron emission tomography (PET) and CT images on a single system. Images from our recently installed digital radiographic unit can be added. Our paper describes our present system, explains the rationale for its configuration, and describes the directions in which it will expand.

The role of FDG-PET in detecting rejection after liver transplantation.

PubMed

Watson, Ashley M; Bhutiani, Neal; Philips, Prejesh; Davis, Eric G; Eng, Mary; Cannon, Robert M; Jones, Christopher M

2018-05-15

The activation and increased metabolic activity of T cells in acute cellular rejection could allow fluoro-2-deoxyglucose positron emission tomography to be utilized for detection of acute cellular rejection. The objective of this study was to evaluate the effectiveness of fluoro-2-deoxyglucose positron emission tomography in detecting acute cellular rejection in the clinical setting. Fluoro-2-deoxyglucose positron emission tomography studies were performed on 88 orthotopic liver transplant patients at 7 and 17 days postoperatively (first positron emission tomography and second positron emission tomography, respectively). Additional studies were performed if patients had suspicion of rejection and at resolution of rejection (third positron emission tomography and fourth positron emission tomography, respectively). A circular region of interest was placed over the liver for semiquantitative evaluation of fluoro-2-deoxyglucose positron emission tomography images by means of standard uptake values. Eighteen of 88 patients in our study (20.5%) had histologically proven acute cellular rejection during a 16 ± 11 day follow-up. There was no significant difference between the standard uptake values of first positron emission tomography among non-rejecters versus rejecters (2.05 ±0.46 non-rejecters versus 1.82 ± 0.40 rejecters, P = .127). Within the rejection cohort, the standard uptake values from the third positron emission tomography (rejection) were higher compared to the first positron emission tomography (baseline) (2.41 ± 0.48 third positron emission tomography versus 1.82 ± 0.41 first positron emission tomography, P < .001). Increased signal on fluoro-2-deoxyglucose positron emission tomography over baseline is associated with acute cellular rejection in liver transplant recipients. Additional prospective validation studies are essential to define the role of fluoro-2-deoxyglucose positron emission tomography scan as an early marker for acute cellular rejection. Copyright © 2018 Elsevier Inc. All rights reserved.

Applications of slow positrons to cancer research: Search for selectivity of positron annihilation to skin cancer

NASA Astrophysics Data System (ADS)

Jean, Y. C.; Li, Ying; Liu, Gaung; Chen, Hongmin; Zhang, Junjie; Gadzia, Joseph E.

2006-02-01

Slow positrons and positron annihilation spectroscopy (PAS) have been applied to medical research in searching for positron annihilation selectivity to cancer cells. We report the results of positron lifetime and Doppler broadening energy spectroscopies in human skin samples with and without cancer as a function of positron incident energy (up to 8 μm depth) and found that the positronium annihilates at a significantly lower rate and forms at a lower probability in the samples having either basal cell carcinoma (BCC) or squamous cell carcinoma (SCC) than in the normal skin. The significant selectivity of positron annihilation to skin cancer may open a new research area of developing positron annihilation spectroscopy as a novel medical tool to detect cancer formation externally and non-invasively at the early stages.

Application of Timepix3 based CdTe spectral sensitive photon counting detector for PET imaging

NASA Astrophysics Data System (ADS)

Turecek, Daniel; Jakubek, Jan; Trojanova, Eliska; Sefc, Ludek; Kolarova, Vera

2018-07-01

Positron emission tomography (PET) is a nuclear medicine functional imaging technique. It is used in clinical oncology (medical imaging of tumors and the search for metastases), and pre-clinical studies using animals. PET uses small amounts of radioactive materials (radiotracers) and a special photon sensitive camera. Most of these cameras use scintillators with photomultipliers as detectors. However, these detectors have limited energy sensitivity and large pixels. Therefore, the false signal caused by a scattering poses a significant problem. In this work we study properties of position, energy and time sensitive semiconductor detector of Timepix3 type and its applicability for PET measurements. This work presents an initial study and evaluation of two Timepix3 detectors with 2 mm thick CdTe sensors used in simplified geometry for PET imaging. The study is performed on 2 samples - a capillary tube and a cylindrical plexiglass phantom with cavities. Both samples are filled with fluodeoxyglucose (FDG) solution that is used as a radiotracer. The Timepix3 offers better properties compared to conventional detectors - high granularity (55 μm pixel pitch), good energy resolution (1 keV at 60 keV) and sufficient time resolution (1.6 ns). The spectral sensitivity of Timepix3 together with coincidence/anticoincidence technique allows for significant reduction of background signal caused by Compton scattering and internal X-ray fluorescence of Cd and Te.

Manipulation of positron orbits in a dipole magnetic field with fluctuating electric fields

NASA Astrophysics Data System (ADS)

Saitoh, H.; Horn-Stanja, J.; Nißl, S.; Stenson, E. V.; Hergenhahn, U.; Pedersen, T. Sunn; Singer, M.; Dickmann, M.; Hugenschmidt, C.; Stoneking, M. R.; Danielson, J. R.; Surko, C. M.

2018-01-01

We report the manipulation of positron orbits in a toroidal dipole magnetic field configuration realized with electric fields generated by segmented electrodes. When the toroidal circulation motion of positrons in the dipole field is coupled with time-varying electric fields generated by azimuthally segmented outer electrodes, positrons undergo oscillations of their radial positions. This enables quick manipulation of the spatial profiles of positrons in a dipole field trap by choosing appropriate frequency, amplitude, phase, and gating time of the electric fields. According to numerical orbit analysis, we applied these electric fields to positrons injected from the NEPOMUC slow positron facility into a prototype dipole field trap experiment with a permanent magnet. Measurements with annihilation γ-rays clearly demonstrated the efficient compression effects of positrons into the strong magnetic field region of the dipole field configuration. This positron manipulation technique can be used as one of essential tools for future experiments on the formation of electron-positron plasmas.

Matrix Isolation Spectroscopy Applied to Positron Moderatioin in Cryogenic Solids

DTIC Science & Technology

2011-07-01

Current Positron Applications • 2-γ decay exploited in Positron Emission Tomography (PET) scanners. • Positrons localize & annihilate preferentially at...Air Force  Eglin Air Force Base AFRL-RW-EG-TP-2011-024 Matrix Isolation Spectroscopy Applied to Positron Moderation in Cryogenic Solids Distribution... Spectroscopy Applied to Positron Moderation in Cryogenic Solids 5a. CONTRACT NUMBER 5b. GRANT NUMBER 62602F 5c. PROGRAM ELEMENT NUMBER 6

Reflection of Low Energy Positrons from the Surface of Highly Oriented Pyrolytic Graphite and Single Layer Graphene.

NASA Astrophysics Data System (ADS)

Imam, S. K.; Chirayath, V. A.; Chrysler, M. D.; Fairchild, A. J.; Gladen, R. W.; Koymen, A. R.; Weiss, A. H.; UT Arlington Positron Surface Laboratory Team

A time of flight positron annihilation induced Auger electron spectrometer (TOF-PAES) was utilized to measure the reflection of positrons as a function of incident positron energy (0 to 10 eV) from the surface of highly oriented pyrolytic graphite (HOPG) and from a single layer graphene (SLG) on a Cu foil. A NaI scintillation detector was used to measure the annihilation gamma from the reflected positrons as a function of incident positron kinetic energy. The annihilation of the positrons on HOPG and SLG were simultaneously measured using another NaI detector near the sample. The Auger electrons emitted as a result of the annihilation of positrons from the surface of the sample were also measured concurrently. As the positron kinetic energy was increased, the number of reflected positrons calculated from the intensity under the annihilation gamma peak showed a steady decrease. The positronium formation measured at the sample using the gamma spectrum showed a peak at 6 eV. The intensity of the carbon KVV Auger peak showed a dip at the same energy. The correlation of the three signals, intensity of reflected positrons, positrons annihilating at the sample and the Auger intensity are discussed for both samples. This work was supported by NSF Grant No. DMR 1508719 and DMR 1338130.

Methods and apparatus for producing and storing positrons and protons

DOEpatents

Akers, Douglas W [Idaho Falls, ID

2010-07-06

Apparatus for producing and storing positrons may include a trap that defines an interior chamber therein and that contains an electric field and a magnetic field. The trap may further include a source material that includes atoms that, when activated by photon bombardment, become positron emitters to produce positrons. The trap may also include a moderator positioned adjacent the source material. A photon source is positioned adjacent the trap so that photons produced by the photon source bombard the source material to produce the positron emitters. Positrons from the positron emitters and moderated positrons from the moderator are confined within the interior chamber of the trap by the electric and magnetic fields. Apparatus for producing and storing protons are also disclosed.

Positron annihilation in a metal-oxide semiconductor studied by using a pulsed monoenergetic positron beam

NASA Astrophysics Data System (ADS)

Uedono, A.; Wei, L.; Tanigawa, S.; Suzuki, R.; Ohgaki, H.; Mikado, T.; Ohji, Y.

1993-12-01

The positron annihilation in a metal-oxide semiconductor was studied by using a pulsed monoenergetic positron beam. Lifetime spectra of positrons were measured as a function of incident positron energy for a polycrystalline Si(100 nm)/SiO2(400 nm)/Si specimen. Applying a gate voltage between the polycrystalline Si film and the Si substrate, positrons implanted into the specimen were accumulated at the SiO2/Si interface. From the measurements, it was found that the annihilation probability of ortho-positronium (ortho-Ps) drastically decreased at the SiO2/Si interface. The observed inhibition of the Ps formation was attributed to an interaction between positrons and defects at the SiO2/Si interface.

Emittance of positron beams produced in intense laser plasma interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen Hui; Hazi, A.; Link, A.

2013-01-15

The first measurement of the emittance of intense laser-produced positron beams has been made. The emittance values were derived through measurements of positron beam divergence and source size for different peak positron energies under various laser conditions. For one of these laser conditions, we used a one dimensional pepper-pot technique to refine the emittance value. The laser-produced positrons have a geometric emittance between 100 and 500 mm{center_dot}mrad, comparable to the positron sources used at existing accelerators. With 10{sup 10}-10{sup 12} positrons per bunch, this low emittance beam, which is quasi-monoenergetic in the energy range of 5-20 MeV, may be usefulmore » as an alternative positron source for future accelerators.« less

Conceptual design of an intense positron source based on an LIA

NASA Astrophysics Data System (ADS)

Long, Ji-Dong; Yang, Zhen; Dong, Pan; Shi, Jin-Shui

2012-04-01

Accelerator based positron sources are widely used due to their high intensity. Most of these accelerators are RF accelerators. An LIA (linear induction accelerator) is a kind of high current pulsed accelerator used for radiography. A conceptual design of an intense pulsed positron source based on an LIA is presented in the paper. One advantage of an LIA is its pulsed power being higher than conventional accelerators, which means a higher amount of primary electrons for positron generations per pulse. Another advantage of an LIA is that it is very suitable to decelerate the positron bunch generated by bremsstrahlung pair process due to its ability to adjustably shape the voltage pulse. By implementing LIA cavities to decelerate the positron bunch before it is moderated, the positron yield could be greatly increased. These features may make the LIA based positron source become a high intensity pulsed positron source.

Positron confinement in embedded lithium nanoclusters

NASA Astrophysics Data System (ADS)

van Huis, M. A.; van Veen, A.; Schut, H.; Falub, C. V.; Eijt, S. W.; Mijnarends, P. E.; Kuriplach, J.

2002-02-01

Quantum confinement of positrons in nanoclusters offers the opportunity to obtain detailed information on the electronic structure of nanoclusters by application of positron annihilation spectroscopy techniques. In this work, positron confinement is investigated in lithium nanoclusters embedded in monocrystalline MgO. These nanoclusters were created by means of ion implantation and subsequent annealing. It was found from the results of Doppler broadening positron beam analysis that approximately 92% of the implanted positrons annihilate in lithium nanoclusters rather than in the embedding MgO, while the local fraction of lithium at the implantation depth is only 1.3 at. %. The results of two-dimensional angular correlation of annihilation radiation confirm the presence of crystalline bulk lithium. The confinement of positrons is ascribed to the difference in positron affinity between lithium and MgO. The nanocluster acts as a potential well for positrons, where the depth of the potential well is equal to the difference in the positron affinities of lithium and MgO. These affinities were calculated using the linear muffin-tin orbital atomic sphere approximation method. This yields a positronic potential step at the MgO||Li interface of 1.8 eV using the generalized gradient approximation and 2.8 eV using the insulator model.

SPADAS: a high-speed 3D single-photon camera for advanced driver assistance systems

NASA Astrophysics Data System (ADS)

Bronzi, D.; Zou, Y.; Bellisai, S.; Villa, F.; Tisa, S.; Tosi, A.; Zappa, F.

2015-02-01

Advanced Driver Assistance Systems (ADAS) are the most advanced technologies to fight road accidents. Within ADAS, an important role is played by radar- and lidar-based sensors, which are mostly employed for collision avoidance and adaptive cruise control. Nonetheless, they have a narrow field-of-view and a limited ability to detect and differentiate objects. Standard camera-based technologies (e.g. stereovision) could balance these weaknesses, but they are currently not able to fulfill all automotive requirements (distance range, accuracy, acquisition speed, and frame-rate). To this purpose, we developed an automotive-oriented CMOS single-photon camera for optical 3D ranging based on indirect time-of-flight (iTOF) measurements. Imagers based on Single-photon avalanche diode (SPAD) arrays offer higher sensitivity with respect to CCD/CMOS rangefinders, have inherent better time resolution, higher accuracy and better linearity. Moreover, iTOF requires neither high bandwidth electronics nor short-pulsed lasers, hence allowing the development of cost-effective systems. The CMOS SPAD sensor is based on 64 × 32 pixels, each able to process both 2D intensity-data and 3D depth-ranging information, with background suppression. Pixel-level memories allow fully parallel imaging and prevents motion artefacts (skew, wobble, motion blur) and partial exposure effects, which otherwise would hinder the detection of fast moving objects. The camera is housed in an aluminum case supporting a 12 mm F/1.4 C-mount imaging lens, with a 40°×20° field-of-view. The whole system is very rugged and compact and a perfect solution for vehicle's cockpit, with dimensions of 80 mm × 45 mm × 70 mm, and less that 1 W consumption. To provide the required optical power (1.5 W, eye safe) and to allow fast (up to 25 MHz) modulation of the active illumination, we developed a modular laser source, based on five laser driver cards, with three 808 nm lasers each. We present the full characterization of the 3D automotive system, operated both at night and during daytime, in both indoor and outdoor, in real traffic, scenario. The achieved long-range (up to 45m), high dynamic-range (118 dB), highspeed (over 200 fps) 3D depth measurement, and high precision (better than 90 cm at 45 m), highlight the excellent performance of this CMOS SPAD camera for automotive applications.

MO-AB-206-00: Nuclear Medicine Physics and Testing

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This education session will cover the physics and operation principles of gamma cameras and PET scanners. The first talk will focus on PET imaging. An overview of the principles of PET imaging will be provided, including positron decay physics, and the transition from 2D to 3D imaging. More recent advances in hardware and software will be discussed, such as time-of-flight imaging, and improvements in reconstruction algorithms that provide for options such as depth-of-interaction corrections. Quantitative applications of PET will be discussed, as well as the requirements for doing accurate quantitation. Relevant performance tests will also be described. Learning Objectives: Bemore » able to describe basic physics principles of PET and operation of PET scanners. Learn about recent advances in PET scanner hardware technology. Be able to describe advances in reconstruction techniques and improvements Be able to list relevant performance tests. The second talk will focus on gamma cameras. The Nuclear Medicine subcommittee has charged a task group (TG177) to develop a report on the current state of physics testing of gamma cameras, SPECT, and SPECT/CT systems. The report makes recommendations for performance tests to be done for routine quality assurance, annual physics testing, and acceptance tests, and identifies those needed satisfy the ACR accreditation program and The Joint Commission imaging standards. The report is also intended to be used as a manual with detailed instructions on how to perform tests under widely varying conditions. Learning Objectives: At the end of the presentation members of the audience will: Be familiar with the tests recommended for routine quality assurance, annual physics testing, and acceptance tests of gamma cameras for planar imaging. Be familiar with the tests recommended for routine quality assurance, annual physics testing, and acceptance tests of SPECT systems. Be familiar with the tests of a SPECT/CT system that include the CT images for SPECT reconstructions. Become knowledgeable of items to be included in annual acceptance testing reports including CT dosimetry and PACS monitor measurements. T. Turkington, GE Healthcare.« less

Survey of Modular Military Vehicles: Benefits and Burdens

DTIC Science & Technology

2016-01-01

Survey of Modular Military Vehicles: BENEFITS and BURDENS Jean M. Dasch and David J. Gorsich Modularity in military vehicle design is generally...considered a positive attribute that promotes adaptability, resilience, and cost savings. The benefits and burdens of modularity are considered by...Engineering Center, vehicles were considered based on horizontal modularity , vertical modularity , and distributed modularity . Examples were given for each

Theoretical survey on positronium formation and ionisation in positron atom scattering

NASA Technical Reports Server (NTRS)

Basu, Madhumita; Ghosh, A. S.

1990-01-01

The recent theoretical studies are surveyed and reported on the formation of exotic atoms in positron-hydrogen, positron-helium and positron-lithium scattering specially at intermediate energy region. The ionizations of these targets by positron impact was also considered. Theoretical predictions for both the processes are compared with existing measured values.

Development of an Electron-Positron Source for Positron Annihilation Lifetime Spectroscopy

DTIC Science & Technology

2007-01-01

positron source for positron annihilation lifetime spectroscopy Final Report Report Title...Development of an Electron- Positron Source for Position Annihilation Lifetime Spectroscopy DAAD19-03-1-0287 Final Report 2/17/2007... annihilation lifetime spectroscopy REPORT DOCUMENTATION PAGE 18. SECURITY CLASSIFICATION ON THIS PAGE UNCLASSIFIED 2. REPORT DATE: 12b. DISTRIBUTION

Present and future experiments using bright low-energy positron beams

NASA Astrophysics Data System (ADS)

Hugenschmidt, Christoph

2017-01-01

Bright slow positron beams enable not only experiments with drastically reduced measurement time and improved signal-to-noise ratio but also the realization of novel experimental techniques. In solid state physics and materials science positron beams are usually applied for the depth dependent analysis of vacancy-like defects and their chemical surrounding using positron lifetime and (coincident) Doppler broadening spectroscopy. For surface studies, annihilation induced Auger-electron spectroscopy allows the analysis of the elemental composition in the topmost atomic layer, and the atomic positions at the surface can be determined by positron diffraction with outstanding accuracy. In fundamental research low-energy positron beams are used for the production of e.g. cold positronium or positronium negative ions. All the aforementioned experiments benefit from the high intensity of present positron beam facilities. In this paper, we scrutinize the technical constraints limiting the achievable positron intensity and the available kinetic energy at the sample position. Current efforts and future developments towards the generation of high intensity spin-polarized slow positron beams paving the way for new positron experiments are discussed.

High-Altitude Balloon Launches for Effective Education, Inspiration and Research

NASA Astrophysics Data System (ADS)

Voss, H. D.; Dailey, J.; Patterson, D.; Krueger, J.

2006-12-01

Over a three-year period the Taylor University Science Research Training Program (SRTP) has successfully launched and recovered 33 sophisticated payloads to altitudes between 20-33 km (100% success with rapid recovery). All of the payloads included two GPS tracking systems, cameras and monitors, a 110 kbit down link, and uplink command capability for educational experiments (K-12 and undergrad) and nanosatellite subsystem testing. Launches were conducted both day and night, with multiple balloons, with up to 10 experiment boxes, and under varying weather and upper atmospheric conditions. The many launches in a short period of time allowed the payload bus design to evolve toward increased performance, reliability, standardization, simplicity, and modularity for low-cost launch services. The current design uses a Zigbee wireless connection (50 kbaud rate) for each of the payload experiment boxes for rapid assembly and checkout with a common interface board for gathering analog and digital data and for commanding. Common data from each box is processed and displayed using modular LabView software. The use of balloons for active research (ozone, aerosols, cosmic rays. UV, IR, remote sensing, energy, propulsion) significantly invigorates and motivates student development, drives team schedule, uncovers unexpected problems, permits end-to-end closure, and forces calibration and validation of real data. The SRTP has helped to spin off a student company called StratoStar Systems for providing an affordable low-cost balloon launch service capability, insurance plan, and other technical assistance for scientific, industrial and STEM educational use.

Modular low-light microscope for imaging cellular bioluminescence and radioluminescence

PubMed Central

Kim, Tae Jin; Türkcan, Silvan; Pratx, Guillem

2017-01-01

Low-light microscopy methods are receiving increased attention as new applications have emerged. One such application is to allow longitudinal imaging of light-sensitive cells with no phototoxicity and no photobleaching of fluorescent biomarkers. Another application is for imaging signals that are inherently dim and undetectable using standard microscopy, such as bioluminescence, chemiluminescence, or radioluminescence. In this protocol, we provide instructions on how to build a modular low-light microscope (1-4 d) by coupling two microscope objective lenses, back-to-back from each other, using standard optomechanical components. We also provide directions on how to image dim signals such as radioluminescence (1-1.5 h), bioluminescence (∼30 min) and low-excitation fluorescence (∼15 min). In particular, radioluminescence microscopy is explained in detail as it is a newly developed technique, which enables the study of small molecule transport (eg. radiolabeled drugs, metabolic precursors, and nuclear medicine contrast agents) by single cells without perturbing endogenous biochemical processes. In this imaging technique, a scintillator crystal (eg. CdWO4) is placed in close proximity to the radiolabeled cells, where it converts the radioactive decays into optical flashes detectable using a sensitive camera. Using the image reconstruction toolkit provided in this protocol, the flashes can be reconstructed to yield high-resolution image of the radiotracer distribution. With appropriate timing, the three aforementioned imaging modalities may be performed altogether on a population of live cells, allowing the user to perform parallel functional studies of cell heterogeneity at the single-cell level. PMID:28426025

The status of the positron beam facility at NEPOMUC

NASA Astrophysics Data System (ADS)

Hugenschmidt, C.

2011-01-01

The NEutron induced POsitron source MUniCh NEPOMUC provides a high intensity positron beam with 9·108 moderated positrons per second with a primary beam energy of 1keV. After remoderation, the positron beam is magnetically guided to five experimental setups: a coincident Doppler-broadening spectrometer (CDBS), a positron annihilation induced Auger-electron spectrometer (PAES), a pulsed low-energy positron system (PLEPS) as well as an interface for providing a pulsed beam with further improved brightness. An apparatus for the production of the negatively charged positronium ion Ps- is currently in operation at the open multi-purpose beam port, where additional experiments can be realized. Within this contribution, an overview of the positron beam facility NEPOMUC with its instrumentation at the research reactor FRMII is given.

PREFACE: The International Workshop on Positron Studies of Defects 2014

NASA Astrophysics Data System (ADS)

Sugita, Kazuki; Shirai, Yasuharu

2016-01-01

The International Workshop on Positron Studies of Defects 2014 (PSD-14) was held in Kyoto, Japan from 14-19 September, 2014. The PSD Workshop brought together positron scientists interested in studying defects to an international platform for presenting and discussing recent results and achievements, including new experimental and theoretical methods in the field. The workshop topics can be characterized as follows: • Positron studies of defects in semiconductors and oxides • Positron studies of defects in metals • New experimental methods and equipment • Theoretical calculations and simulations of momentum distributions, positron lifetimes and other characteristics for defects • Positron studies of defects in combination with complementary methods • Positron beam studies of defects at surfaces, interfaces, in sub-surface regions and thin films • Nanostructures and amorphous materials

Depth-dependent positron annihilation in different polymers

NASA Astrophysics Data System (ADS)

Yang, J.; Zhang, P.; Cheng, G. D.; Li, D. X.; Wu, H. B.; Li, Z. X.; Cao, X. Z.; Jia, Q. J.; Yu, R. S.; Wang, B. Y.

2013-09-01

Depth-dependent positron annihilation Doppler broadening measurements were conducted for polymers with different chemical compositions. Variations of the S parameter with respect to incident positron energy were observed. For pure hydrocarbons PP, HDPE and oxygen-containing polymer PC, S parameter rises with increasing positron implantation depth. While for PI and fluoropolymers like PTFE, ETFE and PVF, S parameter decreases with higher positron energy. For chlorine-containing polymer PVDC, S parameter remains nearly constant at all incident positron energies. It is suggested that these three variation trends are resulted from a competitive effect between the depth-dependent positronium formation and the influence of highly electronegative atoms on positron annihilation characteristics.

Elastic and inelastic scattering of positrons in gases and solids

NASA Technical Reports Server (NTRS)

Mcgowan, J. W.

1972-01-01

Three apparatuses were designed and built: The first, which is now operative, was designed to study the details of positron thermalization in solids and the subsequent emission of the low energy positrons from moderating foils; The second apparatus now under test is a positron bottle similar in design to an electron trap. It was built to store positrons at a fixed energy and to look at the number of stored positrons (storage time) as a function of a scattering gas in the vacuum chamber. The third apparatus is a crossed beam apparatus where positron-, alkali scattering will be studied. Much of the apparatus is now under test with electrons.

Positron studies in catalysis research

NASA Astrophysics Data System (ADS)

During the past eight months, the authors have made progress in several areas relevant to the eventual use of positron techniques in catalysis research. They have come closer to the completion of their positron microscope, and at the same time have performed several studies in their non-microscopic positron spectrometer which should ultimately be applicable to catalysis. The current status of the efforts in each of these areas is summarized in the following sections: Construction of the positron microscope (optical element construction, data collection software, and electronic sub-assemblies); Doppler broadening spectroscopy of metal silicide; Positron lifetime spectroscopy of glassy polymers; and Positron lifetime measurements of pore-sizes in zeolites.

Application Of Positron Beams For The Characterization Of Nano-scale Pores In Thin Films

NASA Astrophysics Data System (ADS)

Hirata, K.; Ito, K.; Kobayashi, Y.; Suzuki, R.; Ohdaira, T.; Eijt, S. W. H.; Schut, H.; van Veen, A.

2003-08-01

We applied three positron annihilation techniques, positron 3γ-annihilation spectroscopy, positron annihilation lifetime spectroscopy, and angular correlation of annihilation radiation, to the characterization of nano-scale pores in thin films by combining them with variable-energy positron beams. Characterization of pores in thin films is an important part of the research on various thin films of industrial importance. The results of our recent studies on pore characterization of thin films by positron beams will be reported here.

Positron annihilation lifetime and Doppler broadening spectroscopy at the ELBE facility

NASA Astrophysics Data System (ADS)

Wagner, Andreas; Butterling, Maik; Liedke, Maciej O.; Potzger, Kay; Krause-Rehberg, Reinhard

2018-05-01

The Helmholtz-Zentrum Dresden-Rossendorf operates a superconducting linear accelerator for electrons with energies up to 35 MeV and average beam currents up to 1.6 mA with bunch charges up to 120 pC. The electron beam is employed to produce several secondary beams including X-rays from bremsstrahlung production, coherent IR light in a Free Electron Laser, superradiant THz radiation, neutrons, and positrons. The secondary positron beam after moderation feeds the Monoenergetic Positron Source (MePS) where positron annihilation lifetime (PALS) and positron annihilation Doppler-broadening experiments in materials science are performed. The adjustable repetition rate of the continuous-wave electron beams allows matching of the pulse separation to the positron lifetime in the sample under study. The energy of the positron beam can be set between 0.5 keV and 20 keV to perform depth resolved defect spectroscopy and porosity studies especially for thin films. Bulk materials, fluids, gases, and even radioactive samples can be studied at the unique Gamma-induced Positron Source (GiPS) where an intense bremsstrahlung source generates positrons directly inside the material under study. A 22Na-based monoenergetic positron beam serves for offline experiments and additional depth-resolved Doppler-broadening studies complementing both accelerator-based sources.

Positron accumulation effect in particles embedded in a low-density matrix

NASA Astrophysics Data System (ADS)

Dryzek, Jerzy; Siemek, Krzysztof

2015-02-01

Systematic studies of the so-called positron accumulation effect for samples with particles embedded in a matrix are reported. This effect is related to energetic positrons which penetrate inhomogeneous medium. Due to differences in the linear absorption coefficient, different amounts of positrons are accumulated and annihilate in the identical volume of both materials. Positron lifetime spectroscopy and Doppler broadening of the annihilation line using Na-22 positrons were applied to the studies of the epoxy resin samples with embedded micro-sized particles of transition metals, i.e., Ni, Sn, Mo, W, and nonmetal particles, i.e., Si and NaF. The significant difference between the determined fraction of positrons annihilating in the particles and the particle volume fraction indicates the positron accumulation effect. The simple phenomenological model and Monte Carlo simulations are able to describe the main features of the obtained dependencies. The aluminum alloy with embedded Sn nanoparticles is also considered for demonstration differences between the accumulation and another related effect, i.e., the positron affinity.

An open-source, FireWire camera-based, Labview-controlled image acquisition system for automated, dynamic pupillometry and blink detection.

PubMed

de Souza, John Kennedy Schettino; Pinto, Marcos Antonio da Silva; Vieira, Pedro Gabrielle; Baron, Jerome; Tierra-Criollo, Carlos Julio

2013-12-01

The dynamic, accurate measurement of pupil size is extremely valuable for studying a large number of neuronal functions and dysfunctions. Despite tremendous and well-documented progress in image processing techniques for estimating pupil parameters, comparatively little work has been reported on practical hardware issues involved in designing image acquisition systems for pupil analysis. Here, we describe and validate the basic features of such a system which is based on a relatively compact, off-the-shelf, low-cost FireWire digital camera. We successfully implemented two configurable modes of video record: a continuous mode and an event-triggered mode. The interoperability of the whole system is guaranteed by a set of modular software components hosted on a personal computer and written in Labview. An offline analysis suite of image processing algorithms for automatically estimating pupillary and eyelid parameters were assessed using data obtained in human subjects. Our benchmark results show that such measurements can be done in a temporally precise way at a sampling frequency of up to 120 Hz and with an estimated maximum spatial resolution of 0.03 mm. Our software is made available free of charge to the scientific community, allowing end users to either use the software as is or modify it to suit their own needs. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

A novel silicon array designed for intraoperative charged particle imaging.

PubMed

Tornai, Martin P; Patt, Bradley E; Iwanczyk, Jan S; Tull, Carolyn R; MacDonald, Lawrence R; Hoffman, Edward J

2002-11-01

A novel Si-PIN imaging array is under investigation for a charged particle (beta, positron, or alpha) sensitive intraoperative camera to be used for (residual) tumor identification during surgery. This class of collimator-less nuclear imaging device has a higher signal response for direct interactions than its scintillator-optical detector-based counterparts. Monte Carlo simulations with 635 keV betas were performed, yielding maximum and projected ranges of 1.64 and 0.55 mm in Si. Up to 90% of these betas were completely absorbed in the first 0.30 mm. Based on these results, 300 microm thick prototype Si detector arrays were designed in a 16 x 16 crossed-grid arrangement with 0.8 mm wide orthogonal strips on 1.0 mm pitch. A NIM- and CAMAC-based high-density data acquisition and processing system was used to collect the list mode data. The system was calibrated by comparisons of measured spectra to energy deposition simulations or by direct measurement of various >100 keV conversion electron or beta emitters. Mean electronic noise per strip was <3.6 keV FWHM at room temperature. When detecting positrons, which have an accompanying 511 keV annihilation background, the flood irradiated beta/gamma ratio was approximately 40, indicating that beta images could be made without the use of background rejection techniques. The intrinsic spatial resolution corresponds to the 1 x 1 mm2 pixel size, and measurements of beta emitting point and line sources yielded FWHM resolutions of 1.5 (lateral) and 2.5 mm (diagonal), respectively, with the larger widths due to particle range blurting effects. Deconvolution of the finite source size yielded intrinsic resolutions that corresponded to the image pixel size. Transmission images of circle and line phantoms with various hole sizes and pitch were resolved with either pure beta or positron irradiation without a background correction. This novel semiconductor imaging device facilitates high charged particle and low gamma sensitivity, high signal/noise ratio, and allows for compact design to potentially aid surgical guidance by providing in situ images of clinical relevance.

Design of a structural and functional hierarchy for planning and control of telerobotic systems

NASA Technical Reports Server (NTRS)

Acar, Levent; Ozguner, Umit

1989-01-01

Hierarchical structures offer numerous advantages over conventional structures for the control of telerobotic systems. A hierarchically organized system can be controlled via undetailed task assignments and can easily adapt to changing circumstances. The distributed and modular structure of these systems also enables fast response needed in most telerobotic applications. On the other hand, most of the hierarchical structures proposed in the literature are based on functional properties of a system. These structures work best for a few given functions of a large class of systems. In telerobotic applications, all functions of a single system needed to be explored. This approach requires a hierarchical organization based on physical properties of a system and such a hierarchical organization is introduced. The decomposition, organization, and control of the hierarchical structure are considered, and a system with two robot arms and a camera is presented.

Astronaut John Young at LRV prior to deployment of ALSEP during first EVA

NASA Image and Video Library

1972-04-21

AS16-116-18578 (21 April 1972) --- Astronaut John W. Young, commander of the Apollo 16 lunar landing mission, works at the Lunar Roving Vehicle (LRV) just prior to deployment of the Apollo Lunar Surface Experiments Package (ALSEP) during the first extravehicular activity (EVA) on April 21, 1972. Note the Ultraviolet (UV) Camera/Spectrometer to the right of the Lunar Module (LM) ladder. Also, note the pile of protective/thermal foil under the U.S. flag on the LM which the astronauts pulled away to get to the Modular Equipment Storage Assembly (MESA) bay. While astronauts Young and Charles M. Duke Jr., lunar module pilot; descended in the Apollo 16 LM "Orion" to explore the Descartes highlands landing site on the moon, astronaut Thomas K. Mattingly II, command module pilot, remained with the Command and Service Modules (CSM) "Casper" in lunar orbit.

Remote sensing and spectral analysis of plumes from ocean dumping in the New York Bight Apex

NASA Technical Reports Server (NTRS)

Johnson, R. W.

1980-01-01

The application of the remote sensing techniques of aerial photography and multispectral scanning in the qualitative and quantitative analysis of plumes from ocean dumping of waste materials is investigated in the New York Bight Apex. Plumes resulting from the dumping of acid waste and sewage sludge were observed by Ocean Color Scanner at an altitude of 19.7 km and by Modular Multispectral Scanner and mapping camera at an altitude of 3.0 km. Results of the qualitative analysis of multispectral and photographic data for the mapping, location, and identification of pollution features without concurrent sea truth measurements are presented which demonstrate the usefulness of in-scene calibration. Quantitative distributions of the suspended solids in sewage sludge released in spot and line dumps are also determined by a multiple regression analysis of multispectral and sea truth data.

Plant Stem and Leaf Movements in Microgravity. Preliminary Results from a Study Using the EMCS Hardware on the ISS

NASA Astrophysics Data System (ADS)

Johnsson, Anders; Bokn Solheim, Bjarte Gees; Henning Iversen, Tor

2008-06-01

In the 72 days long MULTIGEN-1 experiment movements of Arabidopsis thaliana were recorded using the European Modular Cultivation System, EMCS. One main goal in the experiment was to study possible oscillatory movements of plant parts in weightlessness and under acceleration pulses on centrifuge rotors. Recording was made by video sampling of the plants in cultivation chambers every 5 min. The camera + mirror set-up in the EMCS was developed by alternating the mirror positions to get 'stereoscopic' 2D pictures so that 3D-movements could be constructed. Studies of rhythmic, helical movements of shoots as well as of rhythmic movements of leaves are discussed. It is concluded that gravity amplifies self-sustained circumnutations. Also gravitropical reactions of leaves were successfully documented. The results are of importance, for example in the discussion since Charles Darwin's days on the influence of gravity on circumnutations.

The relative efficiency of modular and non-modular networks of different size

PubMed Central

Tosh, Colin R.; McNally, Luke

2015-01-01

Most biological networks are modular but previous work with small model networks has indicated that modularity does not necessarily lead to increased functional efficiency. Most biological networks are large, however, and here we examine the relative functional efficiency of modular and non-modular neural networks at a range of sizes. We conduct a detailed analysis of efficiency in networks of two size classes: ‘small’ and ‘large’, and a less detailed analysis across a range of network sizes. The former analysis reveals that while the modular network is less efficient than one of the two non-modular networks considered when networks are small, it is usually equally or more efficient than both non-modular networks when networks are large. The latter analysis shows that in networks of small to intermediate size, modular networks are much more efficient that non-modular networks of the same (low) connective density. If connective density must be kept low to reduce energy needs for example, this could promote modularity. We have shown how relative functionality/performance scales with network size, but the precise nature of evolutionary relationship between network size and prevalence of modularity will depend on the costs of connectivity. PMID:25631996

Slow positron applications at slow positron facility of institute of materials structure science, KEK

NASA Astrophysics Data System (ADS)

Hyodo, Toshio; Mochizuki, Izumi; Wada, Ken; Toge, Nobukazu; Shidara, Tetsuo

2018-05-01

Slow Positron Facility at High Energy Accelerator Research Organization (KEK) is a user dedicated facility with an energy-tunable (0.1 - 35 keV) slow positron beam created by a dedicated ˜ 50 MeV linac. It operates in a short pulse (width 1-12 ns, variable, 5×106 e+/s) and a long pulse (width 1.2 µs, 5×107 e+/s) modes of 50 Hz. High energy positrons from pair creation are moderated by reemission after thermalization in W foils. The reemitted positrons are then electrostatically accelerated to a desired energy up to 35 keV and magnetically transported. A pulse-stretching section (pulse stretcher) is installed in the middle of the beamline. It stretches the slow positron pulse for the experiments where too many positrons annihilating in the sample at the same time has to be avoided. Four experiment stations for TRHEPD (total-reflection high-energy positron diffraction), LEPD (low-energy positron diffraction), Ps- (positronium negative ion), and Ps-TOF (positronium time-of-flight) experiments are connected to the beamline branches, SPF-A3, SPF-A4, SPF-B1 and SPF-B2, respectively. Recent results of these stations are briefly described.

Positron annihilation study of the high- Tc (Bi,Pb) 2Sr 2Ca 2Cu 3O x superconductor

NASA Astrophysics Data System (ADS)

Lim, H. J.; Byrne, J. G.

1997-03-01

Positron lifetime spectroscopy (PLS) and positron Doppler-broadening spectroscopy (PDBS) were applied to the high- Tc lead-doped Bi 2Sr 2Ca 2Cu 3O x (BPSCCO 2223) superconductor as a function of temperature. Neither positron lifetimes nor Doppler parameters ( S, W, and{S}/{W}) showed significant change through Tc. This may result from having the highest positron density in the open BiO 2 double layers and no significant positron density in the superconducting CuO 2 layers where positrons, if mainly present, are known to be sensitive to the transition in other high- Tc superconductors. Doppler parameters showed that the probability of positron annihilations with core electrons in the lattice slightly increased and that the probability of positron annihilations with conduction electrons slightly decreased as temperature decreased from ambient temperature to 20 K. The lifetime associated with positron annihilations in the perfect lattice of the sample ( τ1) was 209 ps and, due to the annihilations at internal surfaces or voids in the sample ( τ2) was about 540 ps, independent of temperature. Finally, the mean lifetime for BSCCO 2223 was about 307 ps.

Positron beam studies of solids and surfaces: A summary

NASA Astrophysics Data System (ADS)

Coleman, P. G.

2006-02-01

A personal overview is given of the advances in positron beam studies of solids and surfaces presented at the 10th International Workshop on Positron Beams, held in Doha, Qatar, in March 2005. Solids studied include semiconductors, metals, alloys and insulators, as well as biophysical systems. Surface studies focussed on positron annihilation-induced Auger electron spectroscopy (PAES), but interesting applications of positron-surface interactions in fields as diverse as semiconductor technology and studies of the interstellar medium serve to illustrate once again the breadth of scientific endeavour covered by slow positron beam investigations.

High-yield positron systems for linear colliders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clendenin, J.E.

1989-04-01

Linear colliders, such as the SLC, are among those accelerators for which a high-yield positron source operating at the repetition rate of the accelerator is desired. The SLC, having electron energies up to 50 GeV, presents the possibility of generating positron bunches with useful charge even exceeding that of the initial electron bunch. The exact positron yield to be obtained depends on the particular capture, transport and damping system employed. Using 31 GeV electrons impinging on a W-type converter phase-space at the target to the acceptance of the capture rf section, the SLC source is capable of producing, for everymore » electron, up to two positrons within the acceptance of the positron damping ring. The design of this source and the performance of the positron system as built are described. Also, future prospects and limitations for high-yield positron systems are discussed. 11 refs., 5 figs., 3 tabs.« less

Digitized detection of gamma-ray signals concentrated in narrow time windows for transient positron annihilation lifetime spectroscopy

NASA Astrophysics Data System (ADS)

Kinomura, A.; Suzuki, R.; Oshima, N.; O'Rourke, B. E.; Nishijima, T.; Ogawa, H.

2014-12-01

A pulsed slow-positron beam generated by an electron linear accelerator was directly used for positron annihilation lifetime spectroscopy without any positron storage devices. A waveform digitizer was introduced to simultaneously capture multiple gamma-ray signals originating from positron annihilation events during a single accelerator pulse. The positron pulse was chopped and bunched with the chopper signals also sent to the waveform digitizer. Time differences between the annihilation gamma-ray and chopper peaks were calculated and accumulated as lifetime spectra in a computer. The developed technique indicated that positron annihilation lifetime spectroscopy can be performed in a 20 μs time window at a pulse repetition rate synchronous with the linear accelerator. Lifetime spectra of a Kapton sheet and a thermally grown SiO2 layer on Si were successfully measured. Synchronization of positron lifetime measurements with pulsed ion irradiation was demonstrated by this technique.

The Buffer-Gas Positron Accumulator and Resonances in Positron-Molecule Interactions

NASA Technical Reports Server (NTRS)

Surko, C.M.

2007-01-01

This is a personal account of the development of our buffer-gas positron trap and the new generation of cold beams that these traps enabled. Dick Drachman provided much appreciated advice to us from the time we started the project. The physics underlying trap operation is related to resonances (or apparent resonances) in positron-molecule interactions. Amusingly, experiments enabled by the trap allowed us to understand these processes. The positron-resonance "box score" to date is one resounding "yes," namely vibrational Feshbach resonances in positron annihilation on hydrocarbons; a "probably" for positron-impact electronic excitation of CO and NZ;an d a "maybe" for vibrational excitation of selected molecules. Two of these processes enabled the efficient operation of the trap, and one almost killed it in infancy. We conclude with a brief overview of further applications of the trapping technology discussed here, such as "massive" positron storage and beams with meV energy resolution.

Activity-based costing evaluation of a [(18)F]-fludeoxyglucose positron emission tomography study.

PubMed

Krug, Bruno; Van Zanten, Annie; Pirson, Anne-Sophie; Crott, Ralph; Borght, Thierry Vander

2009-10-01

The aim of the study is to use the activity-based costing approach to give a better insight in the actual cost structure of a positron emission tomography procedure (FDG-PET) by defining the constituting components and by simulating the impact of possible resource or practice changes. The cost data were obtained from the hospital administration, personnel and vendor interviews as well as from structured questionnaires. A process map separates the process in 16 patient- and non-patient-related activities, to which the detailed cost data are related. One-way sensitivity analyses shows to which degree of uncertainty the different parameters affect the individual cost and evaluate the impact of possible resource or practice changes like the acquisition of a hybrid PET/CT device, the patient throughput or the sales price of a 370MBq (18)F-FDG patient dose. The PET centre spends 73% of time in clinical activities and the resting time after injection of the tracer (42%) is the single largest departmental cost element. The tracer cost and the operational time have the most influence on cost per procedure. The analysis shows a total cost per FDG-PET ranging from 859 Euro for a BGO PET camera to 1142 Euro for a 16 slices PET-CT system, with a distribution of the resource costs in decreasing order: materials (44%), equipment (24%), wage (16%), space (6%) and hospital overhead (10%). The cost of FDG-PET is mainly influenced by the cost of the radiopharmaceutical. Therefore, the latter rather than the operational time should be reduced in order to improve its cost-effectiveness.

Adaptive multi-resolution Modularity for detecting communities in networks

NASA Astrophysics Data System (ADS)

Chen, Shi; Wang, Zhi-Zhong; Bao, Mei-Hua; Tang, Liang; Zhou, Ji; Xiang, Ju; Li, Jian-Ming; Yi, Chen-He

2018-02-01

Community structure is a common topological property of complex networks, which attracted much attention from various fields. Optimizing quality functions for community structures is a kind of popular strategy for community detection, such as Modularity optimization. Here, we introduce a general definition of Modularity, by which several classical (multi-resolution) Modularity can be derived, and then propose a kind of adaptive (multi-resolution) Modularity that can combine the advantages of different Modularity. By applying the Modularity to various synthetic and real-world networks, we study the behaviors of the methods, showing the validity and advantages of the multi-resolution Modularity in community detection. The adaptive Modularity, as a kind of multi-resolution method, can naturally solve the first-type limit of Modularity and detect communities at different scales; it can quicken the disconnecting of communities and delay the breakup of communities in heterogeneous networks; and thus it is expected to generate the stable community structures in networks more effectively and have stronger tolerance against the second-type limit of Modularity.

Product modular design incorporating preventive maintenance issues

NASA Astrophysics Data System (ADS)

Gao, Yicong; Feng, Yixiong; Tan, Jianrong

2016-03-01

Traditional modular design methods lead to product maintenance problems, because the module form of a system is created according to either the function requirements or the manufacturing considerations. For solving these problems, a new modular design method is proposed with the considerations of not only the traditional function related attributes, but also the maintenance related ones. First, modularity parameters and modularity scenarios for product modularity are defined. Then the reliability and economic assessment models of product modularity strategies are formulated with the introduction of the effective working age of modules. A mathematical model used to evaluate the difference among the modules of the product so that the optimal module of the product can be established. After that, a multi-objective optimization problem based on metrics for preventive maintenance interval different degrees and preventive maintenance economics is formulated for modular optimization. Multi-objective GA is utilized to rapidly approximate the Pareto set of optimal modularity strategy trade-offs between preventive maintenance cost and preventive maintenance interval difference degree. Finally, a coordinate CNC boring machine is adopted to depict the process of product modularity. In addition, two factorial design experiments based on the modularity parameters are constructed and analyzed. These experiments investigate the impacts of these parameters on the optimal modularity strategies and the structure of module. The research proposes a new modular design method, which may help to improve the maintainability of product in modular design.

Development of mini linac-based positron source and an efficient positronium convertor for positively charged antihydrogen production

NASA Astrophysics Data System (ADS)

Muranaka, T.; Debu, P.; Dupré, P.; Liszkay, L.; Mansoulie, B.; Pérez, P.; Rey, J. M.; Ruiz, N.; Sacquin, Y.; Crivelli, P.; Gendotti, U.; Rubbia, A.

2010-04-01

We have installed in Saclay a facility for an intense positron source in November 2008. It is based on a compact 5.5 MeV electron linac connected to a reaction chamber with a tungsten target inside to produce positrons via pair production. The expected production rate for fast positrons is 5·1011 per second. The study of moderation of fast positrons and the construction of a slow positron trap are underway. In parallel, we have investigated an efficient positron-positronium convertor using porous silica materials. These studies are parts of a project to produce positively charged antihydrogen ions aiming to demonstrate the feasibility of a free fall antigravity measurement of neutral antihydrogen.

Nondestructive monitoring of fatigue damage evolution in austenitic stainless steel by positron-lifetime measurements

NASA Astrophysics Data System (ADS)

Holzwarth, Uwe; Schaaff, Petra

2004-03-01

Positron-lifetime measurements have been performed on austenitic stainless steel during (i) stress- and (ii) strain-controlled fatigue experiments for different applied stress and strain amplitudes, respectively. For this purpose a generator-detector assembly with a 72Se/72As positron generator [maximum activity 25 μCi (0.9 MBq)] has been mounted on mechanical testing machines in order to measure the positron lifetime without removing the specimens from the load train. The average positron lifetime has been determined by a β+-γ coincidence. The feasibility to use the average positron lifetime for monitoring the evolution of fatigue damage and to predict early failure has been examined. In strain- and stress-controlled experiments the average positron lifetime shows a pronounced increase within the first 10% and 40% of the fatigue life, respectively. In stress-controlled experiments the average positron lifetime at failure depends significantly on the applied stress amplitude. In strain-controlled experiments significantly different positron lifetimes for different applied plastic strain amplitudes are obtained within the first 1.000 fatigue cycles, whereas differences get wiped out during further cycling until failure.

The Correlation Between Dislocations and Vacancy Defects Using Positron Annihilation Spectroscopy

NASA Astrophysics Data System (ADS)

Pang, Jinbiao; Li, Hui; Zhou, Kai; Wang, Zhu

2012-07-01

An analysis program for positron annihilation lifetime spectra is only applicable to isolated defects, but is of no use in the presence of defective correlations. Such limitations have long caused problems for positron researchers in their studies of complicated defective systems. In order to solve this problem, we aim to take a semiconductor material, for example, to achieve a credible average lifetime of single crystal silicon under plastic deformation at different temperatures using positron life time spectroscopy. By establishing reasonable positron trapping models with defective correlations and sorting out four lifetime components with multiple parameters, as well as their respective intensities, information is obtained on the positron trapping centers, such as the positron trapping rates of defects, the density of the dislocation lines and correlation between the dislocation lines, and the vacancy defects, by fitting with the average lifetime with the aid of Matlab software. These results give strong grounds for the existence of dislocation-vacancy correlation in plastically deformed silicon, and lay a theoretical foundation for the analysis of positron lifetime spectra when the positron trapping model involves dislocation-related defects.

Development of modularity in the neural activity of childrenʼs brains

NASA Astrophysics Data System (ADS)

Chen, Man; Deem, Michael W.

2015-02-01

We study how modularity of the human brain changes as children develop into adults. Theory suggests that modularity can enhance the response function of a networked system subject to changing external stimuli. Thus, greater cognitive performance might be achieved for more modular neural activity, and modularity might likely increase as children develop. The value of modularity calculated from functional magnetic resonance imaging (fMRI) data is observed to increase during childhood development and peak in young adulthood. Head motion is deconvolved from the fMRI data, and it is shown that the dependence of modularity on age is independent of the magnitude of head motion. A model is presented to illustrate how modularity can provide greater cognitive performance at short times, i.e. task switching. A fitness function is extracted from the model. Quasispecies theory is used to predict how the average modularity evolves with age, illustrating the increase of modularity during development from children to adults that arises from selection for rapid cognitive function in young adults. Experiments exploring the effect of modularity on cognitive performance are suggested. Modularity may be a potential biomarker for injury, rehabilitation, or disease.

Positron Spectroscopy of Hydrothermally Grown Actinide Oxides

DTIC Science & Technology

2014-03-27

POSITRON SPECTROSCOPY OF HYDROTHERMALLY GROWN ACTINIDE OXIDES THESIS Edward C. Schneider...United States Government. AFIT-ENP-14-M-33 POSITRON SPECTROSCOPY OF HYDROTHERMALLY GROWN ACTINIDE OXIDES THESIS...33 POSITRON SPECTROSCOPY OF HYDROTHERMALLY GROWN ACTINIDE OXIDES Edward C. Schneider, BS Captain, USAF Approved

High intensity positron source at HFR: Basic concept, scoring and design optimisation

NASA Astrophysics Data System (ADS)

Zeman, A.; Tuček, K.; Debarberis, L.; Hogenbirk, A.

2012-01-01

Recent applications of positron beam techniques in various fields of research have led to an increasing demand for high intensity positron sources required for advanced applications, particularly in materials science. Considerable efforts are being made worldwide to design and set-up high intensity positron sources and beam systems that are based on several principles. Such positron sources could be used in fundamental and applied research experiments, as well as in industrial applications, especially in the field of condensed matter characterisation at the nanometre scale. Phenomena involving positrons are also important in other applied science fields such as medicine, biology, physics, energy, etc. However, such studies are often limited due to the relative lack of suitable positron sources. Results from the recently completed Exploratory Research Project called "HIPOS" are discussed in this paper, which describes the principles behind such a powerful very high intensity positron beam experimental facility that is based on a reactor source. Details of a proposed concept that uses nuclear reactions [(n, γ) and (γ, pair)] within a designed positron generator at the High Flux Reactor (HFR) in Petten are also discussed. The HIPOS source has been designed to produce slow positrons with intensity of the order of 10 10 e +/s.

Dynamics of modularity of neural activity in the brain during development

NASA Astrophysics Data System (ADS)

Deem, Michael; Chen, Man

2014-03-01

Theory suggests that more modular systems can have better response functions at short times. This theory suggests that greater cognitive performance may be achieved for more modular neural activity, and that modularity of neural activity may, therefore, likely increase with development in children. We study the relationship between age and modularity of brain neural activity in developing children. The value of modularity calculated from fMRI data is observed to increase during childhood development and peak in young adulthood. We interpret these results as evidence of selection for plasticity in the cognitive function of the human brain. We present a model to illustrate how modularity can provide greater cognitive performance at short times and enhance fast, low-level, automatic cognitive processes. Conversely, high-level, effortful, conscious cognitive processes may not benefit from modularity. We use quasispecies theory to predict how the average modularity evolves with age, given a fitness function extracted from the model. We suggest further experiments exploring the effect of modularity on cognitive performance and suggest that modularity may be a potential biomarker for injury, rehabilitation, or disease.

Positron Annihilation in Insulating Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Asoka-Kumar, P; Sterne, PA

2002-10-18

We describe positron results from a wide range of insulating materials. We have completed positron experiments on a range of zeolite-y samples, KDP crystals, alkali halides and laser damaged SiO{sub 2}. Present theoretical understanding of positron behavior in insulators is incomplete and our combined theoretical and experimental approach is aimed at developing a predictive understanding of positrons and positronium annihilation characteristics in insulators. Results from alkali halides and alkaline-earth halides show that positrons annihilate with only the halide ions, with no apparent contribution from the alkali or alkaline-earth cations. This contradicts the results of our existing theory for metals, whichmore » predicts roughly equal annihilation contributions from cation and anion. We also present result obtained using Munich positron microprobe on laser damaged SiO{sub 2} samples.« less

Probing vacancy-type free-volume defects in Li2B4O7 single crystal by positron annihilation lifetime spectroscopy

NASA Astrophysics Data System (ADS)

Shpotyuk, O.; Adamiv, V.; Teslyuk, I.; Ingram, A.; Demchenko, P.

2018-01-01

Vacancy-type free-volume defects in lithium tetraborate Li2B4O7 single crystal, grown by the Czochralski technique, are probed with positron annihilation spectroscopy in the lifetime measuring mode. The experimental positron lifetime spectrum is reconstructed within the three-component fitting, involving channels of positron and positronium Ps trapping, as well as within the two-component fitting with a positronium-compensating source input. Structural configurations of the most efficient positron traps are considered using the crystallographic specificity of lithium tetraborate with the main accent on cation-type vacancies. Possible channels of positron trapping are visualized using the electronic structure calculations with density functional theory at the basis of structural parameters proper to Li2B4O7. Spatially-extended positron-trapping complexes involving singly-ionized lithium vacancies, with character lifetime close to 0.32 ns, are responsible for positron trapping in the nominally undoped lithium tetraborate Li2B4O7 crystal.

The PEPPo method for polarized positrons and PEPPo II

DOE PAGES

Cardman, Lawrence S.

2018-05-01

The Polarized Electrons for Polarized Positrons (PEPPo) experiment at the injector of the Continuous Electron Beam Accelerator Facility demonstrated for the first time the efficient transfer of polarization from electrons to positrons via a two-step process: polarized bremsstrahlung radiation is induced by a polarized electron beam in a high-Z target; then the polarized bremsstrahlung produces polarized positrons via the pair-production process in the same target. Positron polarization up to 82% was measured for an initial electron beam momentum of 8.19 MeV/c, limited only by the electron beam polarization of 85%. This technique extends polarized positron capabilities from GeV to MeVmore » electron beams, and opens access to polarized positron beam physics to a wide community. We present the results of the PEPPo experiment and outline tentative plans for a follow-up experiment that would investigate key aspects of an approach based on PEPPo as a polarized positron source for the 12 GeV Upgrade of CEBAF.« less

Digitized detection of gamma-ray signals concentrated in narrow time windows for transient positron annihilation lifetime spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kinomura, A., E-mail: a.kinomura@aist.go.jp; Suzuki, R.; Oshima, N.

2014-12-15

A pulsed slow-positron beam generated by an electron linear accelerator was directly used for positron annihilation lifetime spectroscopy without any positron storage devices. A waveform digitizer was introduced to simultaneously capture multiple gamma-ray signals originating from positron annihilation events during a single accelerator pulse. The positron pulse was chopped and bunched with the chopper signals also sent to the waveform digitizer. Time differences between the annihilation gamma-ray and chopper peaks were calculated and accumulated as lifetime spectra in a computer. The developed technique indicated that positron annihilation lifetime spectroscopy can be performed in a 20 μs time window at amore » pulse repetition rate synchronous with the linear accelerator. Lifetime spectra of a Kapton sheet and a thermally grown SiO{sub 2} layer on Si were successfully measured. Synchronization of positron lifetime measurements with pulsed ion irradiation was demonstrated by this technique.« less

Slow positron beam production by a 14 MeV C.W. electron accelerator

NASA Astrophysics Data System (ADS)

Begemann, M.; Gräff, G.; Herminghaus, H.; Kalinowsky, H.; Ley, R.

1982-10-01

A 14 MeV c.w. electron accelerator is used for pair production in a tungsten target of 0.7 radiation lengths thickness. A small fraction of the positrons is thermalized and diffuses out of the surface ofsurface of a well annealed tungsten foil coated with MgO which is positioned immediately behind the target. The slow positrons are extracted from the target region and magnetically guided over a distance of 10 m onto a channelplate multiplier at the end of an S-shaped solenoid. The positrons are identified by their annihilation radiation using two NaI-detectors. The intensity of the slow positrons is proportional to the accelerator electron beam current. The maximum intensity of 2.2 × 10 5 slow positrons per second reaching thedetector at an accelerator current of 15 μA was limited by the power deposited in the uncooled target. The energy of the positrons is concentrated in a small region at about 1 eV and clearly demonstrates the emission of thermal positrons.

Measurements of defect structures by positron annihilation lifetime spectroscopy of the tellurite glass TeO2-P2O5-ZnO-LiNbO3 doped with ions of rare earth elements: Er3+, Nd3+ and Gd3+

NASA Astrophysics Data System (ADS)

Golis, E.; Yousef, El. S.; Reben, M.; Kotynia, K.; Filipecki, J.

2015-12-01

The objective of the study was the structural analysis of the TeO2-P2O5-ZnO-LiNbO3 tellurite glasses doped with ions of the rare-earth elements: Er3+, Nd3+ and Gd3+ based on the PALS (Positron Annihilation Lifetime Spectroscopy) method of measuring positron lifetimes. Values of positron lifetimes and the corresponding intensities may be connected with the sizes and number of structural defects, such as vacancies, mono-vacancies, dislocations or pores, the sizes of which range from a few angstroms to a few dozen nanometres. Experimental positron lifetime spectrum revealed existence of two positron lifetime components τ1 and τ2. Their interpretation was based on two-state positron trapping model where the physical parameters are the annihilation velocity and positron trapping rate.

Surface and bulk investigations at the high intensity positron beam facility NEPOMUC

NASA Astrophysics Data System (ADS)

Hugenschmidt, C.; Dollinger, G.; Egger, W.; Kögel, G.; Löwe, B.; Mayer, J.; Pikart, P.; Piochacz, C.; Repper, R.; Schreckenbach, K.; Sperr, P.; Stadlbauer, M.

2008-10-01

The NEutron-induced POsitron source MUniCh (NEPOMUC) at the research reactor FRM II delivers a low-energy positron beam ( E = 15-1000 eV) of high intensity in the range between 4 × 10 7 and 5 × 10 8 moderated positrons per second. At present four experimental facilities are in operation at NEPOMUC: a coincident Doppler-broadening spectrometer (CDBS) for defect spectroscopy and investigations of the chemical vicinity of defects, a positron annihilation-induced Auger-electron spectrometer (PAES) for surface studies and an apparatus for the production of the negatively charged positronium ion Ps -. Recently, the pulsed low-energy positron system (PLEPS) has been connected to the NEPOMUC beam line, and first positron lifetime spectra were recorded within short measurement times. A positron remoderation unit which is operated with a tungsten single crystal in back reflection geometry has been implemented in order to improve the beam brilliance. An overview of NEPOMUC's status, experimental results and recent developments at the running spectrometers are presented.

Slow positron beam generator for lifetime studies

NASA Technical Reports Server (NTRS)

Singh, Jag J. (Inventor); Eftekhari, Abe (Inventor); St.clair, Terry L. (Inventor)

1991-01-01

A slow positron beam generator uses a conductive source residing between two test films. Moderator pieces are placed next to the test film on the opposite side of the conductive source. A voltage potential is applied between the moderator pieces and the conductive source. Incident energetic positrons: (1) are emitted from the conductive source; (2) are passed through test film; and (3) isotropically strike moderator pieces before diffusing out of the moderator pieces as slow positrons, respectively. The slow positrons diffusing out of moderator pieces are attracted to the conductive source which is held at an appropriate potential below the moderator pieces. The slow positrons have to pass through the test films before reaching the conductive source. A voltage is adjusted so that the potential difference between the moderator pieces and the conductive source forces the positrons to stop in the test films. Measurable annihilation radiation is emitted from the test film when positrons annihilate (combine) with electrons in the test film.

Monte Carlo simulation study of positron generation in ultra-intense laser-solid interactions

NASA Astrophysics Data System (ADS)

Yan, Yonghong; Wu, Yuchi; Zhao, Zongqing; Teng, Jian; Yu, Jinqing; Liu, Dongxiao; Dong, Kegong; Wei, Lai; Fan, Wei; Cao, Leifeng; Yao, Zeen; Gu, Yuqiu

2012-02-01

The Monte Carlo transport code Geant4 has been used to study positron production in the transport of laser-produced hot electrons in solid targets. The dependence of the positron yield on target parameters and the hot-electron temperature has been investigated in thick targets (mm-scale), where only the Bethe-Heitler process is considered. The results show that Au is the best target material, and an optimal target thickness exists for generating abundant positrons at a given hot-electron temperature. The positron angular distributions and energy spectra for different hot electron temperatures were studied without considering the sheath field on the back of the target. The effect of the target rear sheath field for positron acceleration was studied by numerical simulation while including an electrostatic field in the Monte Carlo model. It shows that the positron energy can be enhanced and quasi-monoenergetic positrons are observed owing to the effect of the sheath field.

A next generation positron microscope and a survey of candidate samples for future positron studies

NASA Astrophysics Data System (ADS)

Dull, Terry Lou

A positron microscope has been constructed and is nearing the conclusion of its assembly and testing. The instrument is designed to perform positron and electron microscopy in both scanning and magnifying modes. In scanning mode, a small beam of particles is rastered across the target and the amplitude of a positron or electron related signal is recorded as a function of position. For positrons this signal may come from Doppler Broadening Spectroscopy, Reemitted Positron Spectroscopy or Positron Annihilation Lifetime Spectroscopy. For electrons this signal may come from the number of secondary electrons or Auger Electron Spectroscopy. In magnifying mode an incident beam of particles is directed onto the target and emitted particles, either secondary electrons or reemitted positrons, are magnified to form an image. As a positron microscope the instrument will primarily operate in magnifying mode, as a positron reemission microscope. As an electron microscope the instrument will be able to operate in both magnifying and scanning modes. Depth-profiled Doppler Broadening Spectroscopy studies using a non-microscopic low-energy positron beam have also been performed on a series of samples to ascertain the applicability of positron spectroscopies and/or microscopy to their study. All samples have sub-micron film and/or feature size and thus are only susceptible to positron study with low-energy beams. Several stoichiometries and crystallinities of chalcogenide thin films (which can be optically reversibly switched between crystalline states) were studied and a correlation was found to exist between the amorphous/FCC S-parameter difference and the amorphous/FCC switching time. Amorphous silicon films were studied in an attempt to observe the well-established Staebler-Wronski effect as well as the more controversial photodilatation effect. However, DBS was not able to detect either effect. The passive oxide films on titanium and aluminum were studied in an attempt to verify the Point Defect Model, a detailed, but as yet microscopically unconfirmed, theory of the corrosive breakdown of passive films. DBS results supportive of the PDM were observed. Graphitic carbon fibers were also studied and DBS indicated the presence of a 200 nm thick outer fiber skin possibly characterized by a high degree of graphitic crystallite alignment.

Slow positrons in single-crystal samples of Al and Al-AlxOy

NASA Astrophysics Data System (ADS)

Lynn, K. G.; Lutz, H.

1980-11-01

Well-characterized Al(111) and Al(100) samples were studied with monoenergetic positrons before and after exposure to oxygen. Both positronium-formation and positron-emission curves were obtained for various incident positron energies at sample temperatures ranging from 160-900 K. The orthopositronium decay signal provides a unique signature that the positron has emerged from the surface region of a clean metal. In the clean Al crystals part of the positronium formed near the surface is found to be associated with a temperature-activated process described as the thermally activated detrapping of a positron from a surface state. A simple positron diffusion model, including surface and vacancy trapping, is fitted to the positronium data and an estimate of the binding energy of the positron in this trap is made. The positron diffusion constant is found to have a negative temperature dependence before the onset of positron trapping at thermally generated monovacancies (>500 K), in reasonable agreement with theoretical predictions. The depth of the positron surface state is reduced or positronium is formed in the chemisorbed layer as oxygen is adsorbed on both Al sample surfaces, thus increasing the positronium fraction and decreasing the positron emission. At higher oxygen exposures [>500 L (1 L = 10-6 torr sec)] positron or positronium traps are generated in the overlayer and the positronium fraction is reduced. The amorphous-to-crystalline surface transition of AlxOy on Al is observed between 650 and 800 K by the change in the positronium fraction and is interpreted as the removal of trapping centers in the metal-oxide overlayer. At the higher temperatures and incident energies vacancy trapping is observed by the decrease in the positron diffusion length in both the clean and the underlying Al of the oxygen-exposed samples. Similar vacancy formation enthalpies for Al are extracted in both the clean and oxygen-covered samples by a simple model and are in good agreement with those measured by other experimental methods. This technique provides a new experimental means for the study of interfaces and thin films and the vacancy-type defects associated with them.

Development of slow positron beam lines and applications

NASA Astrophysics Data System (ADS)

Mondal, Nagendra Nath

2018-05-01

A positron is an antiparticle of an electron that can be formed in diverse methods: natural or artificial β-decay process, fission and fusion reactions, and a pair production of electron-positron occurred in the reactor and the high energy accelerator centers. Usually a long-lifetime radio isotope is customized for the construction of a slow positron beam lines in many laboratories. The typical intensity of this beam depends upon the strength of the positron source, moderator efficiency, and guiding, pulsing, focusing and detecting systems. This article will review a few positron beam lines and their potential applications in research, especially in the Positronium Bose-Einstein Condensation.

Production of Highly Polarized Positrons Using Polarized Electrons at MeV Energies

NASA Astrophysics Data System (ADS)

Abbott, D.; Adderley, P.; Adeyemi, A.; Aguilera, P.; Ali, M.; Areti, H.; Baylac, M.; Benesch, J.; Bosson, G.; Cade, B.; Camsonne, A.; Cardman, L. S.; Clark, J.; Cole, P.; Covert, S.; Cuevas, C.; Dadoun, O.; Dale, D.; Dong, H.; Dumas, J.; Fanchini, E.; Forest, T.; Forman, E.; Freyberger, A.; Froidefond, E.; Golge, S.; Grames, J.; Guèye, P.; Hansknecht, J.; Harrell, P.; Hoskins, J.; Hyde, C.; Josey, B.; Kazimi, R.; Kim, Y.; Machie, D.; Mahoney, K.; Mammei, R.; Marton, M.; McCarter, J.; McCaughan, M.; McHugh, M.; McNulty, D.; Mesick, K. E.; Michaelides, T.; Michaels, R.; Moffit, B.; Moser, D.; Muñoz Camacho, C.; Muraz, J.-F.; Opper, A.; Poelker, M.; Réal, J.-S.; Richardson, L.; Setiniyaz, S.; Stutzman, M.; Suleiman, R.; Tennant, C.; Tsai, C.; Turner, D.; Ungaro, M.; Variola, A.; Voutier, E.; Wang, Y.; Zhang, Y.; PEPPo Collaboration

2016-05-01

The Polarized Electrons for Polarized Positrons experiment at the injector of the Continuous Electron Beam Accelerator Facility has demonstrated for the first time the efficient transfer of polarization from electrons to positrons produced by the polarized bremsstrahlung radiation induced by a polarized electron beam in a high-Z target. Positron polarization up to 82% have been measured for an initial electron beam momentum of 8.19 MeV /c , limited only by the electron beam polarization. This technique extends polarized positron capabilities from GeV to MeV electron beams, and opens access to polarized positron beam physics to a wide community.

Positronics of subnanometer atomistic imperfections in solids as a high-informative structure characterization tool.

PubMed

Shpotyuk, Oleh; Filipecki, Jacek; Ingram, Adam; Golovchak, Roman; Vakiv, Mykola; Klym, Halyna; Balitska, Valentyna; Shpotyuk, Mykhaylo; Kozdras, Andrzej

2015-01-01

Methodological possibilities of positron annihilation lifetime (PAL) spectroscopy applied to characterize different types of nanomaterials treated within three-term fitting procedure are critically reconsidered. In contrast to conventional three-term analysis based on admixed positron- and positronium-trapping modes, the process of nanostructurization is considered as substitutional positron-positronium trapping within the same host matrix. Developed formalism allows estimate interfacial void volumes responsible for positron trapping and characteristic bulk positron lifetimes in nanoparticle-affected inhomogeneous media. This algorithm was well justified at the example of thermally induced nanostructurization occurring in 80GeSe2-20Ga2Se3 glass.

Production of Highly Polarized Positrons Using Polarized Electrons at MeV Energies

DOE PAGES

Abbott, D.; Adderley, P.; Adeyemi, A.; ...

2016-05-27

The Polarized Electrons for Polarized Positrons experiment at the injector of the Continuous Electron Beam Accelerator Facility has demonstrated for the first time the efficient transfer of polarization from electrons to positrons produced by the polarized bremsstrahlung radiation induced by a polarized electron beam in a high-Z target. Positron polarization up to 82% have been measured for an initial electron beam momentum of 8.19~MeV/c, limited only by the electron beam polarization. We report that this technique extends polarized positron capabilities from GeV to MeV electron beams, and opens access to polarized positron beam physics to a wide community.

Positronics of subnanometer atomistic imperfections in solids as a high-informative structure characterization tool

NASA Astrophysics Data System (ADS)

Shpotyuk, Oleh; Filipecki, Jacek; Ingram, Adam; Golovchak, Roman; Vakiv, Mykola; Klym, Halyna; Balitska, Valentyna; Shpotyuk, Mykhaylo; Kozdras, Andrzej

2015-02-01

Methodological possibilities of positron annihilation lifetime (PAL) spectroscopy applied to characterize different types of nanomaterials treated within three-term fitting procedure are critically reconsidered. In contrast to conventional three-term analysis based on admixed positron- and positronium-trapping modes, the process of nanostructurization is considered as substitutional positron-positronium trapping within the same host matrix. Developed formalism allows estimate interfacial void volumes responsible for positron trapping and characteristic bulk positron lifetimes in nanoparticle-affected inhomogeneous media. This algorithm was well justified at the example of thermally induced nanostructurization occurring in 80GeSe2-20Ga2Se3 glass.

Positron states and annihilation characteristics of surface-trapped positrons at the oxidized Cu(110) surface

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Olenga, Antoine; Weiss, A. H.

2013-03-01

The process by which oxide layers are formed on metal surfaces is still not well understood. In this work we present the results of theoretical studies of positron states and annihilation characteristics of surface-trapped positrons at the oxidized Cu(110) surface. An ab-initio investigation of stability and associated electronic properties of different adsorption phases of oxygen on Cu(110) has been performed on the basis of density functional theory and using DMOl3 code. The changes in the positron work function and the surface dipole moment when oxygen atoms occupy on-surface and sub-surface sites have been attributed to charge redistribution within the first two layers, buckling effects within each layer and interlayer expansion. The computed positron binding energy, positron surface state wave function, and annihilation probabilities of surface trapped positrons with relevant core electrons demonstrate their sensitivity to oxygen coverage, elemental content, atomic structure of the topmost layers of surfaces, and charge transfer effects. Theoretical results are compared with experimental data obtained from studies of oxidized transition metal surfaces using positron annihilation induced Auger electron spectroscopy. This work was supported in part by the National Science Foundation Grant DMR-0907679.

Stable confinement of electron plasma and initial results on positron injection in RT-1

NASA Astrophysics Data System (ADS)

Saitoh, H.; Yoshida, Z.; Morikawa, J.; Yano, Y.; Kasaoka, N.; Sakamoto, W.; Nogami, T.

2013-03-01

The Ring Trap 1 (RT-1) device is a dipole field configuration generated by a levitated superconducting magnet. It offers very interesting opportunities for research on the fundamental properties on non-neutral plasmas, such as self-organization of charged particles in the strongly positive and negative charged particles on magnetic surfaces. When strong positron sources will be available in the future, the dipole field configuration will be potentially applicable to the formation of an electron-positron plasma. We have realized stable, long trap of toroidal pure electron plasma in RT-1; Magnetic levitation of the superconducting magnet resulted in more than 300s of confinement for electron plasma of ˜ 1011 m-3. Aiming for the confinement of positrons as a next step, we started a positron injection experiment. For the formation of positron plasma in the closed magnetic surfaces, one of the key issues to be solved is the efficient injection method of positron across closed magnetic surfaces. In contrast to linear configurations, toroidal configurations have the advantage that they are capable of trapping high energy positrons in the dipole field configuration and consider the possibility of direct trapping of positrons emitted from a 22Na source.

Positrons in surface physics

NASA Astrophysics Data System (ADS)

Hugenschmidt, Christoph

2016-12-01

Within the last decade powerful methods have been developed to study surfaces using bright low-energy positron beams. These novel analysis tools exploit the unique properties of positron interaction with surfaces, which comprise the absence of exchange interaction, repulsive crystal potential and positron trapping in delocalized surface states at low energies. By applying reflection high-energy positron diffraction (RHEPD) one can benefit from the phenomenon of total reflection below a critical angle that is not present in electron surface diffraction. Therefore, RHEPD allows the determination of the atom positions of (reconstructed) surfaces with outstanding accuracy. The main advantages of positron annihilation induced Auger-electron spectroscopy (PAES) are the missing secondary electron background in the energy region of Auger-transitions and its topmost layer sensitivity for elemental analysis. In order to enable the investigation of the electron polarization at surfaces low-energy spin-polarized positrons are used to probe the outermost electrons of the surface. Furthermore, in fundamental research the preparation of well defined surfaces tailored for the production of bound leptonic systems plays an outstanding role. In this report, it is envisaged to cover both the fundamental aspects of positron surface interaction and the present status of surface studies using modern positron beam techniques.

Positron astrophysics and areas of relation to low-energy positron physics

NASA Astrophysics Data System (ADS)

Guessoum, Nidhal

2014-05-01

I briefly review our general knowledge of positron astrophysics, focusing mostly on the theoretical and modelling aspects. The experimental/observational aspects of the topic have recently been reviewed elsewhere [E. Churazov et al., Mon. Nat. R. Astron. Soc. 411, 1727 (2011); N. Prantazos et al., Rev. Mod. Phys. 83, 1001 (2011)]. In particular, I highlight the interactions and cross sections of the reactions that the positrons undergo in various cosmic media. Indeed, these must be of high interest to both the positron astrophysics community and the low-energy positron physics community in trying to find common areas of potential collaboration for the future or areas of research that will help the astrophysics community make further progress on the problem. The processes undergone by positrons from the moments of their birth to their annihilation (in the interstellar medium or other locations) are thus examined. The physics of the positron interactions with gases and solids (dust grains) and the physical conditions and characteristics of the environments where the processes of energy loss, positronium formation, and annihilation take place, are briefly reviewed. An explanation is given about how all the relevant physical information is taken into account in order to calculate annihilation rates and spectra of the 511 keV emission in the ISM; special attention is paid to positron interactions with dust and with polycyclic aromatic hydrocarbons. In particular, an attempt is made to show to what extent the interactions between positrons and interstellar dust grains are similar to laboratory experiments in which beams of low-energy positrons impinge upon solids and surfaces. Sample results are shown for the effect of dust grains on positron annihilation spectra in some phases of the ISM which, together with high resolution spectra measured by satellites, can be used to infer useful knowledge about the environment where the annihilation is predominantly taking place, and ultimately about the birth place and history of positrons in the Galaxy. The important complementarity between work done by the astrophysical and the positron physics communities is emphasised, and attempts are made to suggest avenues of future research for progress in the two fields. Contribution to the Topical Issue "Electron and Positron Induced Processes", edited by Michael Brunger, Radu Campeanu, Masamitsu Hoshino, Oddur Ingólfsson, Paulo Limão-Vieira, Nigel Mason, Yasuyuki Nagashima and Hajime Tanuma.

A machine learning method for fast and accurate characterization of depth-of-interaction gamma cameras

NASA Astrophysics Data System (ADS)

Pedemonte, Stefano; Pierce, Larry; Van Leemput, Koen

2017-11-01

Measuring the depth-of-interaction (DOI) of gamma photons enables increasing the resolution of emission imaging systems. Several design variants of DOI-sensitive detectors have been recently introduced to improve the performance of scanners for positron emission tomography (PET). However, the accurate characterization of the response of DOI detectors, necessary to accurately measure the DOI, remains an unsolved problem. Numerical simulations are, at the state of the art, imprecise, while measuring directly the characteristics of DOI detectors experimentally is hindered by the impossibility to impose the depth-of-interaction in an experimental set-up. In this article we introduce a machine learning approach for extracting accurate forward models of gamma imaging devices from simple pencil-beam measurements, using a nonlinear dimensionality reduction technique in combination with a finite mixture model. The method is purely data-driven, not requiring simulations, and is applicable to a wide range of detector types. The proposed method was evaluated both in a simulation study and with data acquired using a monolithic gamma camera designed for PET (the cMiCE detector), demonstrating the accurate recovery of the DOI characteristics. The combination of the proposed calibration technique with maximum- a posteriori estimation of the coordinates of interaction provided a depth resolution of  ≈1.14 mm for the simulated PET detector and  ≈1.74 mm for the cMiCE detector. The software and experimental data are made available at http://occiput.mgh.harvard.edu/depthembedding/.

Development of a vision-based pH reading system

NASA Astrophysics Data System (ADS)

Hur, Min Goo; Kong, Young Bae; Lee, Eun Je; Park, Jeong Hoon; Yang, Seung Dae; Moon, Ha Jung; Lee, Dong Hoon

2015-10-01

pH paper is generally used for pH interpretation in the QC (quality control) process of radiopharmaceuticals. pH paper is easy to handle and useful for small samples such as radio-isotopes and radioisotope (RI)-labeled compounds for positron emission tomography (PET). However, pHpaper-based detecting methods may have some errors due limitations of eye sight and inaccurate readings. In this paper, we report a new device for pH reading and related software. The proposed pH reading system is developed with a vision algorithm based on the RGB library. The pH reading system is divided into two parts. First is the reading device that consists of a light source, a CCD camera and a data acquisition (DAQ) board. To improve the accuracy of the sensitivity, we utilize the three primary colors of the LED (light emission diode) in the reading device. The use of three colors is better than the use of a single color for a white LED because of wavelength. The other is a graph user interface (GUI) program for a vision interface and report generation. The GUI program inserts the color codes of the pH paper into the database; then, the CCD camera captures the pH paper and compares its color with the RGB database image in the reading mode. The software captures and reports information on the samples, such as pH results, capture images, and library images, and saves them as excel files.

77 FR 71802 - Guidance on Investigational New Drug Applications for Positron Emission Tomography Drugs...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-04

...] Guidance on Investigational New Drug Applications for Positron Emission Tomography Drugs; Availability... Positron Emission Tomography (PET) Drugs.'' The guidance is intended to assist manufacturers of PET drugs... ``Investigational New Drug Applications for Positron Emission Tomography (PET) Drugs.'' The guidance summarizes the...

Positron Emission Tomography (PET) and Positron Scanning

Science.gov Websites

National Laboratory 'Positron Emission Tomography ... [is a medical imaging technique that] can track human brain.' Edited excerpts from from Medical Applications of Non-Medical Research: Applications Technical Report, November 1988 High-resolution PET (Positron Emission Tomography) for Medical Science

Modular Courses in British Higher Education: A Critical Assessment

ERIC Educational Resources Information Center

Church, Clive

1975-01-01

The trends towards modular course structures is examined. British conceptions of modularization are compared with American interpretations of modular instruction, the former shown to be concerned almost exclusively with content, the latter attempting more radical changes in students' learning behavior. Rationales for British modular schemes are…

The multi-scattering model for calculations of positron spatial distribution in the multilayer stacks, useful for conventional positron measurements

NASA Astrophysics Data System (ADS)

Dryzek, Jerzy; Siemek, Krzysztof

2013-08-01

The spatial distribution of positrons emitted from radioactive isotopes into stacks or layered samples is a subject of the presented report. It was found that Monte Carlo (MC) simulations using GEANT4 code are not able to describe correctly the experimental data of the positron fractions in stacks. The mathematical model was proposed for calculations of the implantation profile or positron fractions in separated layers or foils being components of a stack. The model takes into account only two processes, i.e., the positron absorption and backscattering at interfaces. The mathematical formulas were applied in the computer program called LYS-1 (layers profile analysis). The theoretical predictions of the model were in the good agreement with the results of the MC simulations for the semi infinite sample. The experimental verifications of the model were performed on the symmetrical and non-symmetrical stacks of different foils. The good agreement between the experimental and calculated fractions of positrons in components of a stack was achieved. Also the experimental implantation profile obtained using the depth scanning of positron implantation technique is very well described by the theoretical profile obtained within the proposed model. The LYS-1 program allows us also to calculate the fraction of positrons which annihilate in the source, which can be useful in the positron spectroscopy.

Positron annihilation induced Auger electron spectroscopy

NASA Technical Reports Server (NTRS)

Weiss, Alex; Koymen, A. R.; Mehl, David; Jensen, K. O.; Lei, Chun; Lee, K. H.

1990-01-01

Recently, Weiss et al. have demonstrated that it is possible to excite Auger transitions by annihilating core electrons using a low energy (less than 30eV) beam of positrons. This mechanism makes possible a new electron spectroscopy, Positron annihilation induced Auger Electron Spectroscopy (PAES). The probability of exciting an Auger transition is proportional to the overlap of the positron wavefunction with atomic core levels. Since the Auger electron energy provides a signature of the atomic species making the transition, PAES makes it possible to determine the overlap of the positron wavefunction with a particular element. PAES may therefore provide a means of detecting positron-atom complexes. Measurements of PAES intensities from clean and adsorbate covered Cu surfaces are presented which indicate that approx. 5 percent of positrons injected into CU at 25eV produce core annihilations that result in Auger transitions.

Positron annihilation in the nuclear outflows of the Milky Way

NASA Astrophysics Data System (ADS)

Panther, Fiona H.; Crocker, Roland M.; Birnboim, Yuval; Seitenzahl, Ivo R.; Ruiter, Ashley J.

2018-02-01

Observations of soft gamma rays emanating from the Milky Way from SPI/INTEGRAL reveal the annihilation of ˜2 × 1043 positrons every second in the Galactic bulge. The origin of these positrons, which annihilate to produce a prominent emission line centred at 511 keV, has remained mysterious since their discovery almost 50 yr ago. A plausible origin for the positrons is in association with the intense star formation ongoing in the Galactic centre. Moreover, there is strong evidence for a nuclear outflow in the Milky Way. We find that advective transport and subsequent annihilation of positrons in such an outflow cannot simultaneously replicate the observed morphology of positron annihilation in the Galactic bulge and satisfy the requirement that 90 per cent of positrons annihilate once the outflow has cooled to 104 K.

A Comparison of Four-Image Reconstruction Algorithms for 3-D PET Imaging of MDAPET Camera Using Phantom Data

NASA Astrophysics Data System (ADS)

Baghaei, H.; Wong, Wai-Hoi; Uribe, J.; Li, Hongdi; Wang, Yu; Liu, Yaqiang; Xing, Tao; Ramirez, R.; Xie, Shuping; Kim, Soonseok

2004-10-01

We compared two fully three-dimensional (3-D) image reconstruction algorithms and two 3-D rebinning algorithms followed by reconstruction with a two-dimensional (2-D) filtered-backprojection algorithm for 3-D positron emission tomography (PET) imaging. The two 3-D image reconstruction algorithms were ordered-subsets expectation-maximization (3D-OSEM) and 3-D reprojection (3DRP) algorithms. The two rebinning algorithms were Fourier rebinning (FORE) and single slice rebinning (SSRB). The 3-D projection data used for this work were acquired with a high-resolution PET scanner (MDAPET) with an intrinsic transaxial resolution of 2.8 mm. The scanner has 14 detector rings covering an axial field-of-view of 38.5 mm. We scanned three phantoms: 1) a uniform cylindrical phantom with inner diameter of 21.5 cm; 2) a uniform 11.5-cm cylindrical phantom with four embedded small hot lesions with diameters of 3, 4, 5, and 6 mm; and 3) the 3-D Hoffman brain phantom with three embedded small hot lesion phantoms with diameters of 3, 5, and 8.6 mm in a warm background. Lesions were placed at different radial and axial distances. We evaluated the different reconstruction methods for MDAPET camera by comparing the noise level of images, contrast recovery, and hot lesion detection, and visually compared images. We found that overall the 3D-OSEM algorithm, especially when images post filtered with the Metz filter, produced the best results in terms of contrast-noise tradeoff, and detection of hot spots, and reproduction of brain phantom structures. Even though the MDAPET camera has a relatively small maximum axial acceptance (/spl plusmn/5 deg), images produced with the 3DRP algorithm had slightly better contrast recovery and reproduced the structures of the brain phantom slightly better than the faster 2-D rebinning methods.

Performance Evaluation of 18F Radioluminescence Microscopy Using Computational Simulation

PubMed Central

Wang, Qian; Sengupta, Debanti; Kim, Tae Jin; Pratx, Guillem

2017-01-01

Purpose Radioluminescence microscopy can visualize the distribution of beta-emitting radiotracers in live single cells with high resolution. Here, we perform a computational simulation of 18F positron imaging using this modality to better understand how radioluminescence signals are formed and to assist in optimizing the experimental setup and image processing. Methods First, the transport of charged particles through the cell and scintillator and the resulting scintillation is modeled using the GEANT4 Monte-Carlo simulation. Then, the propagation of the scintillation light through the microscope is modeled by a convolution with a depth-dependent point-spread function, which models the microscope response. Finally, the physical measurement of the scintillation light using an electron-multiplying charge-coupled device (EMCCD) camera is modeled using a stochastic numerical photosensor model, which accounts for various sources of noise. The simulated output of the EMCCD camera is further processed using our ORBIT image reconstruction methodology to evaluate the endpoint images. Results The EMCCD camera model was validated against experimentally acquired images and the simulated noise, as measured by the standard deviation of a blank image, was found to be accurate within 2% of the actual detection. Furthermore, point-source simulations found that a reconstructed spatial resolution of 18.5 μm can be achieved near the scintillator. As the source is moved away from the scintillator, spatial resolution degrades at a rate of 3.5 μm per μm distance. These results agree well with the experimentally measured spatial resolution of 30–40 μm (live cells). The simulation also shows that the system sensitivity is 26.5%, which is also consistent with our previous experiments. Finally, an image of a simulated sparse set of single cells is visually similar to the measured cell image. Conclusions Our simulation methodology agrees with experimental measurements taken with radioluminescence microscopy. This in silico approach can be used to guide further instrumentation developments and to provide a framework for improving image reconstruction. PMID:28273348

Dissociation of modular total hip arthroplasty at the neck-stem interface without dislocation.

PubMed

Kouzelis, A; Georgiou, C S; Megas, P

2012-12-01

Modular femoral and acetabular components are now widely used, but only a few complications related to the modularity itself have been reported. We describe a case of dissociation of the modular total hip arthroplasty (THA) at the femoral neck-stem interface during walking. The possible causes of this dissociation are discussed. Successful treatment was provided with surgical revision and replacement of the modular neck components. Surgeons who use modular components in hip arthroplasties should be aware of possible early complications in which the modularity of the prostheses is the major factor of failure.

Quasispecies theory for evolution of modularity.

PubMed

Park, Jeong-Man; Niestemski, Liang Ren; Deem, Michael W

2015-01-01

Biological systems are modular, and this modularity evolves over time and in different environments. A number of observations have been made of increased modularity in biological systems under increased environmental pressure. We here develop a quasispecies theory for the dynamics of modularity in populations of these systems. We show how the steady-state fitness in a randomly changing environment can be computed. We derive a fluctuation dissipation relation for the rate of change of modularity and use it to derive a relationship between rate of environmental changes and rate of growth of modularity. We also find a principle of least action for the evolved modularity at steady state. Finally, we compare our predictions to simulations of protein evolution and find them to be consistent.

Water-sensitive positron trapping modes in nanoporous magnesium aluminate ceramics

NASA Astrophysics Data System (ADS)

Filipecki, J.; Ingram, A.; Klym, H.; Shpotyuk, O.; Vakiv, M.

2007-08-01

The water-sensitive positron trapping modes in nanoporous MgAl2O4 ceramics with a spinel structure are studied. It is shown that water-sorption processes in magnesium aluminate ceramics leads to corresponding increase in positron trapping rates of extended defects located near intergranual boundaries. This catalytic affect has reversible nature, being strongly dependent on sorption water fluxes in ceramics. The fixation of all water-dependent positron trapping inputs allow to refine the most significant changes in positron trapping rate of extended defects.

Positron lifetime beam for defect studies in thin epitaxial semiconductor structures

NASA Astrophysics Data System (ADS)

Laakso, A.; Saarinen, K.; Hautojärvi, P.

2001-12-01

Positron annihilation spectroscopies are methods for direct identification of vacancy-type defects by measuring positron lifetime and Doppler broadening of annihilation radiation and providing information about open volume, concentration and atoms surrounding the defect. Both these techniques are easily applied to bulk samples. Only the Doppler broadening spectroscopy can be employed in thin epitaxial samples by utilizing low-energy positron beams. Here we describe the positron lifetime beam which will provide us with a method to measure lifetime in thin semiconductor layers.

Self-organized modularization in evolutionary algorithms.

PubMed

Dauscher, Peter; Uthmann, Thomas

2005-01-01

The principle of modularization has proven to be extremely successful in the field of technical applications and particularly for Software Engineering purposes. The question to be answered within the present article is whether mechanisms can also be identified within the framework of Evolutionary Computation that cause a modularization of solutions. We will concentrate on processes, where modularization results only from the typical evolutionary operators, i.e. selection and variation by recombination and mutation (and not, e.g., from special modularization operators). This is what we call Self-Organized Modularization. Based on a combination of two formalizations by Radcliffe and Altenberg, some quantitative measures of modularity are introduced. Particularly, we distinguish Built-in Modularity as an inherent property of a genotype and Effective Modularity, which depends on the rest of the population. These measures can easily be applied to a wide range of present Evolutionary Computation models. It will be shown, both theoretically and by simulation, that under certain conditions, Effective Modularity (as defined within this paper) can be a selection factor. This causes Self-Organized Modularization to take place. The experimental observations emphasize the importance of Effective Modularity in comparison with Built-in Modularity. Although the experimental results have been obtained using a minimalist toy model, they can lead to a number of consequences for existing models as well as for future approaches. Furthermore, the results suggest a complex self-amplification of highly modular equivalence classes in the case of respected relations. Since the well-known Holland schemata are just the equivalence classes of respected relations in most Simple Genetic Algorithms, this observation emphasizes the role of schemata as Building Blocks (in comparison with arbitrary subsets of the search space).

[Modular enteral nutrition in pediatrics].

PubMed

Murillo Sanchís, S; Prenafeta Ferré, M T; Sempere Luque, M D

1991-01-01

Modular Enteral Nutrition may be a substitute for Parenteral Nutrition in children with different pathologies. Study of 4 children with different pathologies selected from a group of 40 admitted to the Maternal-Childrens Hospital "Valle de Hebrón" in Barcelona, who received modular enteral nutrition. They were monitored on a daily basis by the Dietician Service. Modular enteral nutrition consists of modules of proteins, peptides, lipids, glucids and mineral salts-vitamins. 1.--Craneo-encephalic traumatisms with loss of consciousness, Feeding with a combination of parenteral nutrition and modular enteral nutrition for 7 days. In view of the tolerance and good results of the modular enteral nutrition, the parenteral nutrition was suspended and modular enteral nutrition alone used up to a total of 43 days. 2.--55% burns with 36 days of hyperproteic modular enteral nutrition together with normal feeding. A more rapid recovery was achieved with an increase in total proteins and albumin. 3.--Persistent diarrhoea with 31 days of modular enteral nutrition, 5 days on parenteral nutrition alone and 8 days on combined parenteral nutrition and modular enteral nutrition. In view of the tolerance and good results of the modular enteral nutrition, the parenteral nutrition was suspended. 4.--Mucoviscidosis with a total of 19 days on modular enteral nutrition, 12 of which were exclusively on modular enteral nutrition and 7 as a night supplement to normal feeding. We administered proteic intakes of up to 20% of the total calorific intake and in concentrations of up to 1.2 calories/ml of the final preparation, always with a good tolerance. Modular enteral nutrition can and should be used as a substitute for parenteral nutrition in children with different pathologies, thus preventing the complications inherent in parenteral nutrition.

Convergent evolution of modularity in metabolic networks through different community structures.

PubMed

Zhou, Wanding; Nakhleh, Luay

2012-09-14

It has been reported that the modularity of metabolic networks of bacteria is closely related to the variability of their living habitats. However, given the dependency of the modularity score on the community structure, it remains unknown whether organisms achieve certain modularity via similar or different community structures. In this work, we studied the relationship between similarities in modularity scores and similarities in community structures of the metabolic networks of 1021 species. Both similarities are then compared against the genetic distances. We revisited the association between modularity and variability of the microbial living environments and extended the analysis to other aspects of their life style such as temperature and oxygen requirements. We also tested both topological and biological intuition of the community structures identified and investigated the extent of their conservation with respect to the taxonomy. We find that similar modularities are realized by different community structures. We find that such convergent evolution of modularity is closely associated with the number of (distinct) enzymes in the organism's metabolome, a consequence of different life styles of the species. We find that the order of modularity is the same as the order of the number of the enzymes under the classification based on the temperature preference but not on the oxygen requirement. Besides, inspection of modularity-based communities reveals that these communities are graph-theoretically meaningful yet not reflective of specific biological functions. From an evolutionary perspective, we find that the community structures are conserved only at the level of kingdoms. Our results call for more investigation into the interplay between evolution and modularity: how evolution shapes modularity, and how modularity affects evolution (mainly in terms of fitness and evolvability). Further, our results call for exploring new measures of modularity and network communities that better correspond to functional categorizations.

Investigation of Positron Sticking to the Surfaces of Topological Insulators

NASA Astrophysics Data System (ADS)

Shastry, K.; Joglekar, P. V.; Olenga, A. Y.; Fazleev, N. G.; Weiss, A. H.; Barniellini, B.

2013-03-01

We describe experiments aimed at probing the sticking of positrons to the surfaces of topological insulators. In these experiments, a magnetically beam will be used to deposit positrons at the surface of Bi2Te2Se. The energy spectra and intensities of electrons emitted as a result of Positron Annihilation induced Auger electron Spectroscopy (PAES) provides a distinct element specific signal which can be used to determine if positrons can be trapped efficiently into a surface localized bound state. The experiments are aimed at determining the practicality of using positron annihilation to selectively probe the critically important top most layer of topological insulator system. Welch Y1100, NSF DMR 0907679

Positron lifetime spectrometer using a DC positron beam

DOEpatents

Xu, Jun; Moxom, Jeremy

2003-10-21

An entrance grid is positioned in the incident beam path of a DC beam positron lifetime spectrometer. The electrical potential difference between the sample and the entrance grid provides simultaneous acceleration of both the primary positrons and the secondary electrons. The result is a reduction in the time spread induced by the energy distribution of the secondary electrons. In addition, the sample, sample holder, entrance grid, and entrance face of the multichannel plate electron detector assembly are made parallel to each other, and are arranged at a tilt angle to the axis of the positron beam to effectively separate the path of the secondary electrons from the path of the incident positrons.

A clinical pilot study of a modular video-CT augmentation system for image-guided skull base surgery

NASA Astrophysics Data System (ADS)

Liu, Wen P.; Mirota, Daniel J.; Uneri, Ali; Otake, Yoshito; Hager, Gregory; Reh, Douglas D.; Ishii, Masaru; Gallia, Gary L.; Siewerdsen, Jeffrey H.

2012-02-01

Augmentation of endoscopic video with preoperative or intraoperative image data [e.g., planning data and/or anatomical segmentations defined in computed tomography (CT) and magnetic resonance (MR)], can improve navigation, spatial orientation, confidence, and tissue resection in skull base surgery, especially with respect to critical neurovascular structures that may be difficult to visualize in the video scene. This paper presents the engineering and evaluation of a video augmentation system for endoscopic skull base surgery translated to use in a clinical study. Extension of previous research yielded a practical system with a modular design that can be applied to other endoscopic surgeries, including orthopedic, abdominal, and thoracic procedures. A clinical pilot study is underway to assess feasibility and benefit to surgical performance by overlaying CT or MR planning data in realtime, high-definition endoscopic video. Preoperative planning included segmentation of the carotid arteries, optic nerves, and surgical target volume (e.g., tumor). An automated camera calibration process was developed that demonstrates mean re-projection accuracy (0.7+/-0.3) pixels and mean target registration error of (2.3+/-1.5) mm. An IRB-approved clinical study involving fifteen patients undergoing skull base tumor surgery is underway in which each surgery includes the experimental video-CT system deployed in parallel to the standard-of-care (unaugmented) video display. Questionnaires distributed to one neurosurgeon and two otolaryngologists are used to assess primary outcome measures regarding the benefit to surgical confidence in localizing critical structures and targets by means of video overlay during surgical approach, resection, and reconstruction.

HyBIS - a low cost, multi-purpose, modular vehicle for detailed ocean mapping

NASA Astrophysics Data System (ADS)

Huehnerbach, V.; Murton, B.; Berndt, C.; Garrard, J.; Wollatz-Vogt, M.; Wetzel, G.; Matthiessen, T.

2013-12-01

HyBIS is a low-cost, multi-purpose, highly maneuverable, fibre-optic controlled survey and sampling robotic underwater vehicle (RUV) capable of diving to 6000m. Built in the UK by Hydro-Lek Ltd. in collaboration with the National Oceanography Centre, Southampton, it has proven itself during recent discoveries of the deepest hydrothermal vents in the world, at 5100m deep in the Cayman Trough in the Caribbean and habitat mapping of seamounts in the Atlantic and Indian oceans . The vehicle has a modular design, with the top module being a command and power system that comprises power management, cameras, lights, hydraulics, thrusters and telemetry. The lower module can alternatively be a clam-shell sampling grab, a manipulator-arm and tool sled, a winch for instrument recovery, or an ocean bottom seismometer deployment module. Unlike a conventional ROV, HyBIS does not have any floatation, rather it is suspended by its umbilical cable directly from the ship. The advantage of direct suspension is that HyBIS can recover or deploy a payload of up to 700kg, although this comes at the price of reduced maneuverability compared to a 'normal' ROV. During its four years of service, HyBIS has, so far, accumulated an impressive list of achievements: recording over 450 hours of HD video footage, thousands of HD still images, collected geological, biological samples, as well as fluids and gas from over 40 different sites. It has also recovered two different seabed landers containing scientific equipment worth over £300k, and placed Ocean Bottom Seismometers onto the seafloor.

Studies of Oxidation of the Cu(100) Surface Using Low Energy Positrons

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Maddox, W. B.; Nadesalingam, M.; Rajeshwar, K.; Weiss, A. H.

2009-03-01

Changes in the surface of an oxidized Cu(100) single crystal resulting from vacuum annealing have been investigated using positron annihilation induced Auger electron spectroscopy (PAES). PAES measurements show a large increase in the intensity of the positron annihilation induced Cu M2,3VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300° C. The intensity then decreases monotonically as the annealing temperature is increased to ˜600° C. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface, surface reconstructions, and electron-positron correlations effects. Possible explanation for the observed behavior of the intensity of positron annihilation induced Cu M2,3VV Auger peak with changes of the annealing temperature is proposed.

Studies of oxidation of the Cu(100) surface using low energy positrons.

NASA Astrophysics Data System (ADS)

Maddox, W. B.; Fazleev, N. G.; Weiss, A. H.

2009-03-01

Changes in the surface of an oxidized Cu(100) single crystal resulting from vacuum annealing have been investigated using positron annihilation induced Auger electron spectroscopy (PAES). PAES measurements show a large increase in the intensity of the positron annihilation induced Cu M2,3VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300^o C. The intensity then decreases monotonically as the annealing temperature is increased to ˜600^o C. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface, surface reconstructions, and electron-positron correlations effects. Possible explanation for the observed behavior of the intensity of positron annihilation induced Cu M2,3VV Auger peak with changes of the annealing temperature is proposed.

Improving depth resolutions in positron beam spectroscopy by concurrent ion-beam sputtering

NASA Astrophysics Data System (ADS)

John, Marco; Dalla, Ayham; Ibrahim, Alaa M.; Anwand, Wolfgang; Wagner, Andreas; Böttger, Roman; Krause-Rehberg, Reinhard

2018-05-01

The depth resolution of mono-energetic positron annihilation spectroscopy using a positron beam is shown to improve by concurrently removing the sample surface layer during positron beam spectroscopy. During ion-beam sputtering with argon ions, Doppler-broadening spectroscopy is performed with energies ranging from 3 keV to 5 keV allowing for high-resolution defect studies just below the sputtered surface. With this technique, significantly improved depth resolutions could be obtained even at larger depths when compared to standard positron beam experiments which suffer from extended positron implantation profiles at higher positron energies. Our results show that it is possible to investigate layered structures with a thickness of about 4 microns with significantly improved depth resolution. We demonstrated that a purposely generated ion-beam induced defect profile in a silicon sample could be resolved employing the new technique. A depth resolution of less than 100 nm could be reached.

Sgr A* as Source of the Positrons Observed in the Galactic Center Region

NASA Astrophysics Data System (ADS)

Jean, Pierre; Guessoum, Nidhal; Ferrière, Katia

2017-01-01

We explore the possibility that a substantial fraction of the positrons observed to annihilate in the central region of our Galaxy come from the supermassive black hole Sgr A* that lies at the center. This idea was proposed by several authors, but the propagation of the emitted positrons into the bulge and beyond remained a serious problem for models of the origin of GC positrons. We assume models of positron production with different energies. The propagation of positrons from their production site is followed in detail with Monte-Carlo simulations, taking into account the physical conditions of the propagation regions as well as various physical interactions. Using the known physics of positron annihilation in astrophysical environments, we calculate the properties of the annihilation emission (time evolution and spatial distribution) for the different models under consideration. We present the results of these simulations and the conclusions/constraints that can be inferred from them.

Positron Annihilation Ratio Spectroscopy (PsARS) Applied to Positronium Formation Studies

DTIC Science & Technology

2010-03-01

POSITRON ANNIHILATION RATIO SPECTROSCOPY (PsARS) APPLIED TO POSITRONIUM FORMATION STUDIES THESIS...AFIT/GNE/ENP/10-M07 POSITRON ANNIHILATION RATIO SPECTROSCOPY (PsARS) APPLIED TO POSITRONIUM FORMATION STUDIES ...lifetime studies in local electric field experiments. High local electric fields can polarize a positron -electron pair, which may result in an extended

Positron studies of metal-oxide-semiconductor structures

NASA Astrophysics Data System (ADS)

Au, H. L.; Asoka-Kumar, P.; Nielsen, B.; Lynn, K. G.

1993-03-01

Positron annihilation spectroscopy provides a new probe to study the properties of interface traps in metal-oxide semiconductors (MOS). Using positrons, we have examined the behavior of the interface traps as a function of gate bias. We propose a simple model to explain the positron annihilation spectra from the interface region of a MOS capacitor.

The stationary non-equilibrium plasma of cosmic-ray electrons and positrons

NASA Astrophysics Data System (ADS)

Tomaschitz, Roman

2016-06-01

The statistical properties of the two-component plasma of cosmic-ray electrons and positrons measured by the AMS-02 experiment on the International Space Station and the HESS array of imaging atmospheric Cherenkov telescopes are analyzed. Stationary non-equilibrium distributions defining the relativistic electron-positron plasma are derived semi-empirically by performing spectral fits to the flux data and reconstructing the spectral number densities of the electronic and positronic components in phase space. These distributions are relativistic power-law densities with exponential cutoff, admitting an extensive entropy variable and converging to the Maxwell-Boltzmann or Fermi-Dirac distributions in the non-relativistic limit. Cosmic-ray electrons and positrons constitute a classical (low-density high-temperature) plasma due to the low fugacity in the quantized partition function. The positron fraction is assembled from the flux densities inferred from least-squares fits to the electron and positron spectra and is subjected to test by comparing with the AMS-02 flux ratio measured in the GeV interval. The calculated positron fraction extends to TeV energies, predicting a broad spectral peak at about 1 TeV followed by exponential decay.

Scattering of positrons and electrons by alkali atoms

NASA Technical Reports Server (NTRS)

Stein, T. S.; Kauppila, W. E.; Kwan, C. K.; Lukaszew, R. A.; Parikh, S. P.; Wan, Y. J.; Zhou, S.; Dababneh, M. S.

1990-01-01

Absolute total scattering cross sections (Q sub T's) were measured for positrons and electrons colliding with sodium, potassium, and rubidium in the 1 to 102 eV range, using the same apparatus and experimental approach (a beam transmission technique) for both projectiles. The present results for positron-sodium and -rubidium collisions represent the first Q sub T measurements reported for these collision systems. Features which distinguish the present comparisons between positron- and electron-alkali atom Q sub T's from those for other atoms and molecules (room-temperature gases) which have been used as targets for positrons and electrons are the proximity of the corresponding positron- and electron-alkali atom Q sub T's over the entire energy range of overlap, with an indication of a merging or near-merging of the corresponding positron and electron Q sub T's near (and above) the relatively low energy of about 40 eV, and a general tendency for the positron-alkali atom Q sub T's to be higher than the corresponding electron values as the projectile energy is decreased below about 40 eV.

Positron annihilation lifetime study of polyvinylpyrrolidone for nanoparticle-stabilizing pharmaceuticals.

PubMed

Shpotyuk, O; Bujňáková, Z; Baláž, P; Ingram, A; Shpotyuk, Y

2016-01-05

Positron annihilation lifetime spectroscopy was applied to characterize free-volume structure of polyvinylpyrrolidone used as nonionic stabilizer in the production of many nanocomposite pharmaceuticals. The polymer samples with an average molecular weight of 40,000 g mol(-1) were pelletized in a single-punch tableting machine under an applied pressure of 0.7 GPa. Strong mixing in channels of positron and positronium trapping were revealed in the polyvinylpyrrolidone pellets. The positron lifetime spectra accumulated under normal measuring statistics were analysed in terms of unconstrained three- and four-term decomposition, the latter being also realized under fixed 0.125 ns lifetime proper to para-positronium self-annihilation in a vacuum. It was shown that average positron lifetime extracted from each decomposition was primary defined by long-lived ortho-positronium component. The positron lifetime spectra treated within unconstrained three-term fitting were in obvious preference, giving third positron lifetime dominated by ortho-positronium pick-off annihilation in a polymer matrix. This fitting procedure was most meaningful, when analysing expected positron trapping sites in polyvinylpyrrolidone-stabilized nanocomposite pharmaceuticals. Copyright © 2015 Elsevier B.V. All rights reserved.

Evidence for a positron bound state on the surface of a topological insulator

NASA Astrophysics Data System (ADS)

Shastry, K.; Weiss, A. H.; Barbiellini, B.; Assaf, B. A.; Lim, Z. H.; Joglekar, P. V.; Heiman, D.

2015-06-01

We describe experiments aimed at probing the sticking of positrons to the surfaces of topological insulators using the Positron Annihilation induced Auger Electron Spectrometer (PAES). A magnetically guided beam was used to deposit positrons at the surface of Bi2Te2Se sample at energy of ∼2eV. Peaks observed in the energy spectra and intensities of electrons emitted as a result of positron annihilation showed peaks at energies corresponding to Auger peaks in Bi, Teand Se providing clear evidence of Auger emission associated with the annihilation of positrons in a surface bound state. Theoretical estimates of the binding energy of this state are compared with estimates obtained by measuring the incident beam energy threshold for secondary electron emission and the temperature dependence positronium(Ps) emission. The experiments provide strong evidence for the existence of a positron bound state at the surface of Bi2Te2Se and indicate the practicality of using positron annihilation to selectively probe the critically important top most layer of topological insulator system.

Studies of the oxidized Cu(100) surface using positron annihilation induced Auger electron spectroscopy

NASA Astrophysics Data System (ADS)

Maddox, W.; Fazleev, N. G.; Nadesalingam, M. P.; Weiss, A. H.

2008-03-01

We discuss recent progress in studies of an oxidized Cu(100) single crystal subjected to vacuum annealing over a temperature range from 293K to 1073K using positron annihilation induced Auger electron spectroscopy (PAES). The PAES measurements show a large monotonic increase in the intensity of the positron annihilation induced Cu M2,3 VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 573 K. The intensity then decreases monotonically as the annealing temperature is increased to 873 K. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface, surface reconstructions, and electron-positron correlations effects. The effects of oxygen adsorption and surface reconstruction on localization of positron surface state wave functions and annihilation characteristics are analyzed. Possible explanations are provided for the observed behavior of the intensity of positron annihilation induced Cu M2,3VV Auger peak with changes of the annealing temperature.

Study of SiO2-Si and metal-oxide-semiconductor structures using positrons

NASA Astrophysics Data System (ADS)

Leung, T. C.; Asoka-Kumar, P.; Nielsen, B.; Lynn, K. G.

1993-01-01

Studies of SiO2-Si and metal-oxide-semiconductor (MOS) structures using positrons are summarized and a concise picture of the present understanding of positrons in these systems is provided. Positron annihilation line-shape S data are presented as a function of the positron incident energy, gate voltage, and annealing, and are described with a diffusion-annihilation equation for positrons. The data are compared with electrical measurements. Distinct annihilation characteristics were observed at the SiO2-Si interface and have been studied as a function of bias voltage and annealing conditions. The shift of the centroid (peak) of γ-ray energy distributions in the depletion region of the MOS structures was studied as a function of positron energy and gate voltage, and the shifts are explained by the corresponding variations in the strength of the electric field and thickness of the depletion layer. The potential role of the positron annihilation technique as a noncontact, nondestructive, and depth-sensitive characterization tool for the technologically important, deeply buried interface is shown.

The Upgrade of the Neutron Induced Positron Source NEPOMUC

NASA Astrophysics Data System (ADS)

Hugenschmidt, C.; Ceeh, H.; Gigl, T.; Lippert, F.; Piochacz, C.; Pikart, P.; Reiner, M.; Weber, J.; Zimnik, S.

2013-06-01

In summer 2012, the new NEutron induced POsitron Source MUniCh (NEPOMUC) was installed and put into operation at the research reactor FRM II. At NEPOMUC upgrade 80% 113Cd enriched Cd is used as neutron-gamma converter in order to ensure an operation time of 25 years. A structure of Pt foils inside the beam tube generates positrons by pair production. Moderated positrons leaving the Pt front foil are electrically extracted and magnetically guided to the outside of the reactor pool. The whole design, including Pt-foils, the electric lenses and the magnetic fields, has been improved in order to enhance both the intensity and the brightness of the positron beam. After adjusting the potentials and the magnetic guide and compensation fields an intensity of about 3·109 moderated positrons per second is expected. During the first start-up, the measured temperatures of about 90°C ensure a reliable operation of the positron source. Within this contribution the features and the status of NEPOMUC upgrade are elucidated. In addition, an overview of recent positron beam experiments and current developments at the spectrometers is given.

Implicit Contractive Mappings in Modular Metric and Fuzzy Metric Spaces

PubMed Central

Hussain, N.; Salimi, P.

2014-01-01

The notion of modular metric spaces being a natural generalization of classical modulars over linear spaces like Lebesgue, Orlicz, Musielak-Orlicz, Lorentz, Orlicz-Lorentz, and Calderon-Lozanovskii spaces was recently introduced. In this paper we investigate the existence of fixed points of generalized α-admissible modular contractive mappings in modular metric spaces. As applications, we derive some new fixed point theorems in partially ordered modular metric spaces, Suzuki type fixed point theorems in modular metric spaces and new fixed point theorems for integral contractions. In last section, we develop an important relation between fuzzy metric and modular metric and deduce certain new fixed point results in triangular fuzzy metric spaces. Moreover, some examples are provided here to illustrate the usability of the obtained results. PMID:25003157

Proposal for a slow positron facility at Jefferson National Laboratory

NASA Astrophysics Data System (ADS)

Mills, Allen P.

2018-05-01

One goal of the JPos-17 International Workshop on Physics with Positrons was to ascertain whether it would be a good idea to expand the mission of the Thomas Jefferson National Accelerator Facility (JLab) to include science with low energy (i.e. "slow") spin polarized positrons. It is probably true that experimentation with slow positrons would potentially have wide-ranging benefits comparable to those obtained with neutron and x-ray scattering, but it is certain that the full range of these benefits will never be fully available without an infrastructure comparable to that of existing neutron and x-ray facilities. The role for Jefferson Laboratory would therefore be to provide and maintain (1) a dedicated set of machines for making and manipulating high intensity, high brightness beams of polarized slow positrons; (2) a suite of unique and easily used instruments of wide utility that will make efficient use of the positrons; and (3) a group of on-site positron scientists to provide scientific leadership, instrument development, and user support. In this note some examples will be given of the science that might make a serious investment in a positron facility worthwhile. At the same time, the lessons learned from various proposed and successful positron facilities will be presented for consideration.

Formation of a high intensity low energy positron string

NASA Astrophysics Data System (ADS)

Donets, E. D.; Donets, E. E.; Syresin, E. M.; Itahashi, T.; Dubinov, A. E.

2004-05-01

The possibility of a high intensity low energy positron beam production is discussed. The proposed Positron String Trap (PST) is based on the principles and technology of the Electron String Ion Source (ESIS) developed in JINR during the last decade. A linear version of ESIS has been used successfully for the production of intense highly charged ion beams of various elements. Now the Tubular Electron String Ion Source (TESIS) concept is under study and this opens really new promising possibilities in physics and technology. In this report, we discuss the application of the tubular-type trap for the storage of positrons cooled to the cryogenic temperatures of 0.05 meV. It is intended that the positron flux at the energy of 1-5 eV, produced by the external source, is injected into the Tubular Positron Trap which has a similar construction as the TESIS. Then the low energy positrons are captured in the PST Penning trap and are cooled down because of their synchrotron radiation in the strong (5-10 T) applied magnetic field. It is expected that the proposed PST should permit storing and cooling to cryogenic temperature of up to 5×109 positrons. The accumulated cooled positrons can be used further for various physics applications, for example, antihydrogen production.

Polarization observables using positron beams

NASA Astrophysics Data System (ADS)

Schmidt, Axel

2018-05-01

The discrepancy between polarized and unpolarized measurements of the proton's electromagnetic form factors is striking, and suggests that two-photon exchange (TPE) may be playing a larger role in elastic electron-proton scattering than is estimated in standard radiative corrections formulae. While TPE is difficult to calculate in a model-independent way, it can be determined experimentally from asymmetries between electron-proton and positron-proton scattering. The possibility of a polarized positron beam at Jefferson Lab would open the door to measurements of TPE using polarization observables. In these proceedings, I examine the feasibility of measuring three such observables with positron scattering. Polarization-transfer, specifically the ɛ-dependence for fixed Q2, is an excellent test of TPE, and the ability to compare electrons and positrons would lead to a drastic reduction of systematics. However, such a measurement would be severely statistically limited. Normal single-spin asymmetries (SSAs) probe the imaginary part of the TPE amplitude and can be improved by simultaneous measurements with electron and positron beams. Beam-normal SSAs are too small to be measured with the proposed polarized positron beam, but target-normal SSAs could be feasibly measured with unpolarized positrons in the spectrometer halls. This technique should be included in the physics case for developing a positron source for Jefferson Lab.

Modular Power Standard for Space Explorations Missions

NASA Technical Reports Server (NTRS)

Oeftering, Richard C.; Gardner, Brent G.

2016-01-01

Future human space exploration will most likely be composed of assemblies of multiple modular spacecraft elements with interconnected electrical power systems. An electrical system composed of a standardized set modular building blocks provides significant development, integration, and operational cost advantages. The modular approach can also provide the flexibility to configure power systems to meet the mission needs. A primary goal of the Advanced Exploration Systems (AES) Modular Power System (AMPS) project is to establish a Modular Power Standard that is needed to realize these benefits. This paper is intended to give the space exploration community a "first look" at the evolving Modular Power Standard and invite their comments and technical contributions.

Oxidation and thermal reduction of the Cu(1 0 0) surface as studied using positron annihilation induced Auger electron spectroscopy (PAES)

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Nadesalingam, M. P.; Maddox, W.; Mukherjee, S.; Rajeshwar, K.; Weiss, A. H.

2010-01-01

Changes in the surface of an oxidized Cu(1 0 0) single crystal resulting from vacuum annealing have been investigated using positron annihilation induced Auger electron spectroscopy (PAES). PAES measurements show a large increase in the intensity of the annihilation induced Cu M 2,3VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300 °C. The intensity then decreases monotonically as the annealing temperature is increased to ˜600 °C. Experimental probabilities of annihilation of surface-trapped positrons with Cu 3p and O 1s core-level electrons are estimated from the measured intensities of the positron annihilation induced Cu M 2,3VV and O KLL Auger transitions. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface, surface reconstructions, and electron-positron correlations effects. The effects of oxygen adsorption on localization of positron surface state wave function and annihilation characteristics are also analyzed. Possible explanation is proposed for the observed behavior of the intensity of positron annihilation induced Cu M 2,3VV and O KLL Auger peaks and probabilities of annihilation of surface-trapped positrons with Cu 3p and O 1s core-level electrons with changes of the annealing temperature.

Enhanced positron trapping by Ag nanoclusters at low temperatures: A challenge of positron sensitivity to quantum dots

NASA Astrophysics Data System (ADS)

Zou, B.; Qi, N.; Liu, Z. W.; Chen, Z. Q.; Liu, H. Q.; Yi, D. Q.; Tang, Z.

2017-03-01

Microstructure evolution of three Al-Ag alloys with different Ag contents (1 wt. % Ag, 5 wt. % Ag, and 15 wt. % Ag) was studied by positron annihilation spectroscopy during the aging process. In situ measurements of the positron lifetime and Doppler broadening of annihilation radiation indicate the fast formation of Ag-rich clusters during natural aging of the alloys. The formation of Ag-rich clusters was further confirmed by coincidence Doppler broadening measurements. The Ag signal reflected by the Coincidence Doppler broadening spectrum increases with increasing Ag content and is further enhanced after subsequent artificial aging at 140 °C. This might be due to the increase in the size of Ag clusters. The temperature dependence of the Doppler broadening spectra between 10 K and 290 K was measured for the Al-Ag alloys after natural and artificial aging. Detrapping of positrons from Ag clusters with increasing temperature was observed for all the three Al-Ag alloys after natural aging and for the Al-1 wt. % Ag after artificial aging. This indicates that Ag clusters act as shallow positron trapping centers. The thermal detrapping of positrons becomes ambiguous with increasing Ag content in the alloy and is nearly invisible in the artificially aged Al-5 wt. % Ag and Al-15 wt. % Ag. The positron binding energy of the Ag cluster is roughly estimated to be about 18.8 meV and 50 meV in the Al-1 wt. % Ag sample after natural aging and artificial aging at 140 °C, respectively, which suggests that the confinement of positrons in the quantum-dot like state depends on the size or chemical composition of clusters. Theoretical calculations confirm positron trapping by Ag nanoclusters, and the confinement of positrons is enhanced with increasing Ag cluster size.

Theoretical calculations of positron annihilation characteristics in inorganic solids -- Recent advances and problems

NASA Astrophysics Data System (ADS)

Sob, M.; Sormann, H.; Kuriplach, J.

Principles and applications of positron annihilation spectroscopy to electronic structure and defect studies are briefly reviewed and some recent advances and pending problems are illustrated by specific examples. In particular, it turns out that the sensitivity of calculated momentum densities of electron-positron annihilation pairs (MDAP) to the choice of electron crystal potential is higher or comparable to its sensitivity with respect to the choice of description of the electron-positron interaction. As a result, it is very hard to distinguish between various electron-positron interaction theories on the basis of the comparison of theoretical and experimental MDAPs. Furthermore, the positron affinity is determined theorttically for several systems having a band gap (semiconductors, insulators). It appears that the calculated positron affinities are significantly underestimated when compared to experimental data and, apparently, electron-positron interactions in such systems are not described satisfactorily by contemporary theoretical approaches. The above examples are related rather to electronic structure studies, but positrons are often used to investigate various open-volume defects in solids, which is dealt with in the last illustration. A non-selfconsistent computational technique suitable for the theoretical examination of configurations having large number (thousands) of non-equivalent atoms has been updated recently to treat non-periodic solids. It is based on the superposition of atomic densities in order to approximate the electronic density of the system studied. Though the charge redistribution due to selfconsistency effects is neglected, positron annihilation characteristics are determined quite reasonably. This allows for studying properties of extended defects like grain boundaries (and other interfaces), dislocations, precipitates, etc., which is very helpful when interpreting experimental positron annihilation data. Our technique is demonstrated for the case of nanocrystalline Ni where realistic atomic configurations are taken from large-scale molecular dynamics simulations.

Dynamic PET/CT measurements of induced positron activity in a prostate cancer patient after 50-MV photon radiation therapy.

PubMed

Janek Strååt, Sara; Jacobsson, Hans; Noz, Marilyn E; Andreassen, Björn; Näslund, Ingemar; Jonsson, Cathrine

2013-01-23

The purpose of this work was to reveal the research interest value of positron emission tomography (PET) imaging in visualizing the induced tissue activity post high-energy photon radiation treatment. More specifically, the focus was on the possibility of retrieving data such as tissue composition and physical half-lives from dynamic PET acquisitions, as positron-emitting radionuclides such as 15O, 11C, and 13N are produced in vivo during radiation treatment with high-energy photons (>15 MeV). The type, amount, and distribution of induced positron-emitting radionuclides depend on the irradiated tissue cross section, the photon spectrum, and the possible perfusion-driven washout. A 62-year-old man diagnosed with prostate cancer was referred for palliative radiation treatment of the pelvis minor. A total dose of 8 Gy was given using high-energy photon beams (50 MV) with a racetrack microtron, and 7 min after the end of irradiation, the patient was positioned in a PET/computed tomography (CT) camera, and a list-mode acquisition was performed for 30 min. Two volumes of interests (VOIs) were positioned on the dynamic PET/CT images, one in the urinary bladder and the other in the subcutaneous fat. Analysis of the measured relative count rate was performed in order to compute the tissue compositions and physical half-lives in the two regions. Dynamic analysis from the two VOIs showed that the decay constants of activated oxygen and carbon could be deduced. Calculation of tissue composition from analyzing the VOI containing subcutaneous fat only moderately agreed with that of the tabulated International Commission on Radiation Units & Measurements (ICRU) data of the adipose tissue. However, the same analysis for the bladder showed a good agreement with that of the tabulated ICRU data. PET can be used in visualizing the induced activity post high-energy photon radiation treatment. Despite the very low count rate in this specific application, wherein 7 min after treatment was about 5% of that of a standard 18F-FDG PET scan, the distribution of activated tissue elements (15O and 11C) could be calculated from the dynamic PET data. One possible future application of this method could possibly be to measure and determine the tumor tissue composition in order to identify any hypoxic or necrotic region, which is information that can be used in the ongoing therapy planning process. The official name of the trial committee of this study is 'Regionala etikprövningsnämnden i Stockholm' (FE 289, Stockholm, SE-17177, Sweden). The unique identifying number is 2011/1789-31/2.

Positronium formation in Ss state in e+-Li scattering

NASA Technical Reports Server (NTRS)

Sarkar, K. P.; Basu, D.; Basu, Madhumita

1990-01-01

There are ample theoretical reasons to investigate positron-alkali atom scattering. Moreover, recent measurement on positron-alkali atom system by a Detroit group has renewed much interest in investigating these processes. Positronium (Ps) formation in excited 2s state in positron-Li scattering at intermediate and high energies were studied including second order effects following Basu and Ghosh.

What is the fate of runaway positrons in tokamaks?

DOE PAGES

Liu, Jian; Qin, Hong; Fisch, Nathaniel J.; ...

2014-06-19

In this study, massive runaway positrons are generated by runaway electrons in tokamaks. The fate of these positrons encodes valuable information about the runaway dynamics. The phase space dynamics of a runaway position is investigated using a Lagrangian that incorporates the tokamak geometry, loop voltage, radiation and collisional effects. It is found numerically that runaway positrons will drift out of the plasma to annihilate on the first wall, with an in-plasma annihilation possibility less than 0.1%. The dynamics of runaway positrons provides signatures that can be observed as diagnostic tools.

What is the fate of runaway positrons in tokamaks?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Jian; Qin, Hong, E-mail: hongqin@ustc.edu.cn; Princeton Plasma Physics Laboratory, Princeton University, Princeton, New Jersey 08543

2014-06-15

Massive runaway positrons are generated by runaway electrons in tokamaks. The fate of these positrons encodes valuable information about the runaway dynamics. The phase space dynamics of a runaway position is investigated using a Lagrangian that incorporates the tokamak geometry, loop voltage, radiation and collisional effects. It is found numerically that runaway positrons will drift out of the plasma to annihilate on the first wall, with an in-plasma annihilation possibility less than 0.1%. The dynamics of runaway positrons provides signatures that can be observed as diagnostic tools.

ANTICOOL: Simulating positron cooling and annihilation in atomic gases

NASA Astrophysics Data System (ADS)

Green, D. G.

2018-03-01

The Fortran program ANTICOOL, developed to simulate positron cooling and annihilation in atomic gases for positron energies below the positronium-formation threshold, is presented. Given positron-atom elastic scattering phase shifts, normalised annihilation rates Zeff, and γ spectra as a function of momentum k, ANTICOOL enables the calculation of the positron momentum distribution f(k , t) as a function of time t, the time-varying normalised annihilation rate Z¯eff(t) , the lifetime spectrum and time-varying annihilation γ spectra. The capability and functionality of the program is demonstrated via a tutorial-style example for positron cooling and annihilation in room temperature helium gas, using accurate scattering and annihilation cross sections and γ spectra calculated using many-body theory as input.

Experimental and computational studies of positron-stimulated ion desorption from TiO2(1 1 0) surface

NASA Astrophysics Data System (ADS)

Yamashita, T.; Hagiwara, S.; Tachibana, T.; Watanabe, K.; Nagashima, Y.

2017-11-01

Experimental and computational studies of the positron-stimulated O+ ion desorption process from a TiO2(1 1 0) surface are reported. The measured data indicate that the O+ ion yields depend on the positron incident energy in the energy range between 0.5 keV and 15 keV. This dependence is closely related to the fraction of positrons which diffuse back to the surface after thermalization in the bulk. Based on the experimental and computational results, we conclude that the ion desorption via positron-stimulation occurs dominantly by the annihilation of surface-trapped positrons with core electrons of the topmost surface atoms.

Binding matter with antimatter: the covalent positron bond.

PubMed

Charry, Jorge Alfonso; Varella, Marcio T Do N; Reyes, Andrés

2018-05-16

We report sufficient theoretical evidence of the energy stability of the e⁺H₂²⁻ molecule, formed by two H⁻ anions and one positron. Analysis of the electronic and positronic densities of the latter compound undoubtedly points out the formation of a positronic covalent bond between the otherwise repelling hydride anions. The lower limit for the bonding energy of the e⁺H₂²⁻ molecule is 74 kJ/mol (0.77 eV), accounting for the zero-point vibrational correction. The formation of a non electronic covalent bond is fundamentally distinct from positron attachment to stable molecules, as the latter process is characterized by a positron affinity, analogous to the electron affinity. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

INSTRUMENTS AND METHODS OF INVESTIGATION: Positron annihilation spectroscopy in materials structure studies

NASA Astrophysics Data System (ADS)

Grafutin, Viktor I.; Prokop'ev, Evgenii P.

2002-01-01

A relatively new method of materials structure analysis — positron annihilation spectroscopy (PAS) — is reviewed. Measurements of positron lifetimes, the determination of positron 3γ- and 2γ-annihilation probabilities, and an investigation of the effects of different external factors on the fundamental characteristics of annihilation constitute the basis for this promising method. The ways in which the positron annihilation process operates in ionic crystals, semiconductors, metals and some condensed matter systems are analyzed. The scope of PAS is described and its prospects for the study of the electronic and defect structures are discussed. The applications of positron annihilation spectroscopy in radiation physics and chemistry of various substances as well as in physics and chemistry of solutions are exemplified.

Configurable double-sided modular jet impingement assemblies for electronics cooling

DOEpatents

Zhou, Feng; Dede, Ercan Mehmet

2018-05-22

A modular jet impingement assembly includes an inlet tube fluidly coupled to a fluid inlet, an outlet tube fluidly coupled to a fluid outlet, and a modular manifold having a first distribution recess extending into a first side of the modular manifold, a second distribution recess extending into a second side of the modular manifold, a plurality of inlet connection tubes positioned at an inlet end of the modular manifold, and a plurality of outlet connection tubes positioned at an outlet end of the modular manifold. A first manifold insert is removably positioned within the first distribution recess, a second manifold insert is removably positioned within the second distribution recess, and a first and second heat transfer plate each removably coupled to the modular manifold. The first and second heat transfer plates each comprise an impingement surface.

A philosophy for CNS radiotracer design

DOE PAGES

Van de Bittner, Genevieve C.; Ricq, Emily L.; Hooker, Jacob M.

2014-10-01

Decades after its discovery, positron emission tomography (PET) remains the premier tool for imaging neurochemistry in living humans. Technological improvements in radiolabeling methods, camera design, and image analysis have kept PET in the forefront. In addition, the use of PET imaging has expanded because researchers have developed new radiotracers that visualize receptors, transporters, enzymes, and other molecular targets within the human brain. However, of the thousands of proteins in the central nervous system (CNS), researchers have successfully imaged fewer than 40 human proteins. To address the critical need for new radiotracers, this Account expounds on the decisions, strategies, and pitfallsmore » of CNS radiotracer development based on our current experience in this area. We discuss the five key components of radiotracer development for human imaging: choosing a biomedical question, selection of a biological target, design of the radiotracer chemical structure, evaluation of candidate radiotracers, and analysis of preclinical imaging. It is particularly important to analyze the market of scientists or companies who might use a new radiotracer and carefully select a relevant biomedical question(s) for that audience. In the selection of a specific biological target, we emphasize how target localization and identity can constrain this process and discuss the optimal target density and affinity ratios needed for binding-based radiotracers. In addition, we discuss various PET test–retest variability requirements for monitoring changes in density, occupancy, or functionality for new radiotracers. In the synthesis of new radiotracer structures, high-throughput, modular syntheses have proved valuable, and these processes provide compounds with sites for late-stage radioisotope installation. As a result, researchers can manage the time constraints associated with the limited half-lives of isotopes. In order to evaluate brain uptake, a number of methods are available to predict bioavailability, blood–brain barrier (BBB) permeability, and the associated issues of nonspecific binding and metabolic stability. To evaluate the synthesized chemical library, researchers need to consider high-throughput affinity assays, the analysis of specific binding, and the importance of fast binding kinetics. Lastly, we describe how we initially assess preclinical radiotracer imaging, using brain uptake, specific binding, and preliminary kinetic analysis to identify promising radiotracers that may be useful for human brain imaging. Although we discuss these five design components separately and linearly in this Account, in practice we develop new PET-based radiotracers using these design components nonlinearly and iteratively to develop new compounds in the most efficient way possible.« less

A Philosophy for CNS Radiotracer Design

PubMed Central

2015-01-01

Conspectus Decades after its discovery, positron emission tomography (PET) remains the premier tool for imaging neurochemistry in living humans. Technological improvements in radiolabeling methods, camera design, and image analysis have kept PET in the forefront. In addition, the use of PET imaging has expanded because researchers have developed new radiotracers that visualize receptors, transporters, enzymes, and other molecular targets within the human brain. However, of the thousands of proteins in the central nervous system (CNS), researchers have successfully imaged fewer than 40 human proteins. To address the critical need for new radiotracers, this Account expounds on the decisions, strategies, and pitfalls of CNS radiotracer development based on our current experience in this area. We discuss the five key components of radiotracer development for human imaging: choosing a biomedical question, selection of a biological target, design of the radiotracer chemical structure, evaluation of candidate radiotracers, and analysis of preclinical imaging. It is particularly important to analyze the market of scientists or companies who might use a new radiotracer and carefully select a relevant biomedical question(s) for that audience. In the selection of a specific biological target, we emphasize how target localization and identity can constrain this process and discuss the optimal target density and affinity ratios needed for binding-based radiotracers. In addition, we discuss various PET test–retest variability requirements for monitoring changes in density, occupancy, or functionality for new radiotracers. In the synthesis of new radiotracer structures, high-throughput, modular syntheses have proved valuable, and these processes provide compounds with sites for late-stage radioisotope installation. As a result, researchers can manage the time constraints associated with the limited half-lives of isotopes. In order to evaluate brain uptake, a number of methods are available to predict bioavailability, blood–brain barrier (BBB) permeability, and the associated issues of nonspecific binding and metabolic stability. To evaluate the synthesized chemical library, researchers need to consider high-throughput affinity assays, the analysis of specific binding, and the importance of fast binding kinetics. Finally, we describe how we initially assess preclinical radiotracer imaging, using brain uptake, specific binding, and preliminary kinetic analysis to identify promising radiotracers that may be useful for human brain imaging. Although we discuss these five design components separately and linearly in this Account, in practice we develop new PET-based radiotracers using these design components nonlinearly and iteratively to develop new compounds in the most efficient way possible. PMID:25272291

Space Shuttle orbit determination using empirical force modeling of attitude maneuvers for the German MOMS-02/D2 mission

NASA Technical Reports Server (NTRS)

Vonbraun, C.; Reigber, Christoph

1994-01-01

In the spring of 1993, the MOMS-02 (modular Optoelectronic Multispectral Scanner) camera, as part of the second German Spacelab mission aboard STS-55, successfully took digital threefold stereo images of the surface of the Earth. While the mission is experimental in nature, its primary goals are to produce high quality maps and three-dimensional digital terrain models of the Earth's surface. Considerable improvement in the quality of the terrain model can be attained if information about the position and attitude of the camera is included during the adjustment of the image data. One of the primary sources of error in the Shuttle's position is due to the significant attitude maneuvers conducted during the course of the mission. Various arcs, using actual Tracking and Data Relay Satellite (TDRSS) Doppler data of STS-55, were processed to determine how effectively empirical force modeling could be used to solve for the radial, transverse, and normal components of the orbit perturbations caused by these routine maneuvers. Results are presented in terms of overlap-orbit differences in the three components. Comparisons of these differences, before and after the maneuvers are estimated, show that the quality of an orbit can be greatly enhanced with this technique, even if several maneuvers are present. Finally, a discussion is made of some of the difficulties encountered with this approach, and some ideas for future studies are presented.

The optical design concept of SPICA-SAFARI

NASA Astrophysics Data System (ADS)

Jellema, Willem; Kruizinga, Bob; Visser, Huib; van den Dool, Teun; Pastor Santos, Carmen; Torres Redondo, Josefina; Eggens, Martin; Ferlet, Marc; Swinyard, Bruce; Dohlen, Kjetil; Griffin, Doug; Gonzalez Fernandez, Luis Miguel; Belenguer, Tomas; Matsuhara, Hideo; Kawada, Mitsunobu; Doi, Yasuo

2012-09-01

The Safari instrument on the Japanese SPICA mission is a zodiacal background limited imaging spectrometer offering a photometric imaging (R ≍ 2), and a low (R = 100) and medium spectral resolution (R = 2000 at 100 μm) spectroscopy mode in three photometric bands covering the 34-210 μm wavelength range. The instrument utilizes Nyquist sampled filled arrays of very sensitive TES detectors providing a 2’x2’ instantaneous field of view. The all-reflective optical system of Safari is highly modular and consists of an input optics module containing the entrance shutter, a calibration source and a pair of filter wheels, followed by an interferometer and finally the camera bay optics accommodating the focal-plane arrays. The optical design is largely driven and constrained by volume inviting for a compact three-dimensional arrangement of the interferometer and camera bay optics without compromising the optical performance requirements associated with a diffraction- and background-limited spectroscopic imaging instrument. Central to the optics we present a flexible and compact non-polarizing Mach-Zehnder interferometer layout, with dual input and output ports, employing a novel FTS scan mechanism based on magnetic bearings and a linear motor. In this paper we discuss the conceptual design of the focal-plane optics and describe how we implement the optical instrument functions, define the photometric bands, deal with straylight control, diffraction and thermal emission in the long-wavelength limit and interface to the large-format FPA arrays at one end and the SPICA telescope assembly at the other end.

UAV remote sening for precision agriculture

NASA Astrophysics Data System (ADS)

Vigneau, Nathalie; Chéron, Corentin; Mainfroy, Florent; Faroux, Romain

2014-05-01

Airinov offers to farmers, scientists and experimenters (plant breeders, etc.) its technical skills about UAVs, cartography and agronomic remote sensing. The UAV is a 2-m-wingspan flying wing. It can carry away either a RGB camera or a multispectral sensor, which records reflectance in 4 spectral bands. The spectral characteristics of the sensor are modular. Each spectral band is comprised between 400 and 850 nm and the FWHM (Full Width at Half Maximum) is between 10 and 40 nm. The spatial resolution varies according to sensor, flying height and user needs from 15cm/px for multispectral sensor at 150m to 1.5cm/px for RGB camera at 50m. The flight is totally automatic thanks to on-board autopilot, IMU (Inertial Measurement Unit) and GPS. Data processing (unvignetting, mosaicking, correction in reflectance) leads to agronomic variables as LAI (Leaf Area Index) or chlorophyll content for barley, wheat, rape and maize as well as vegetation indices as NDVI (Normalized Difference Vegetation Index). Using these data, Airinov can product advices for farmers as nitrogen preconisation for rape. For scientists, Airinov offers trial plot monitoring by micro-plots vectorisation and numerical data exctraction micro-plot by micro-plot. This can lead to kinetic curve for LAI or NDVI to compare cover establishment for different genotypes for example. Airinov's system is a new way to monitor plots with a lot of data (biophysical or biochemical parameters) at high rate, high spatial resolution and high precision.

Investigation of hydrogen interaction with defects in zirconia

NASA Astrophysics Data System (ADS)

Melikhova, O.; Kuriplach, J.; Čížek, J.; Procházka, I.; Brauer, G.; Anwand, W.

2010-04-01

Defect studies of a ZrO2 + 9 mol. % Y2O3 single crystal were performed in this work using a high resolution positron lifetime spectroscopy combined with slow positron implantation spectroscopy. In order to elucidate the nature of positron trapping sites observed experimentally, the structural relaxations of several types of vacancy-like defects in zirconia were performed and positron characteristics for them were calculated. Relaxed atomic configurations of studied defects were obtained by means of ab initio pseudopotential method within the supercell approach. Theoretical calculations indicated that neither oxygen vacancies nor their neutral complexes with substitute yttrium atoms are capable of positron trapping. On the other hand, zirconium vacancies are deep positron traps and are most probably responsible for the saturated positron trapping observed in yttria stabilized zirconia single crystals. However, the calculated positron lifetime for zirconium vacancy is apparently longer than the experimental value corresponding to a single-component spectrum measured for the cubic ZrO2 + 9 mol. % Y2O3 single crystal. It was demonstrated that this effect can be explained by hydrogen trapped in zirconium vacancies. On the basis of structure relaxations, we found that zirconium vacancy - hydrogen complexes represent deep positron traps with the calculated lifetime close to the experimental one. In zirconium vacancy - hydrogen complexes the hydrogen atom forms an O-H bond with one of the nearest neighbour oxygen atoms. The calculated bond length is close to 1 Å.

Studies of Positrons Trapped at Quantum-Dot Like Particles Embedded in Metal Surfaces

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Nadesalingam, M. P.; Weiss, A. H.

2009-03-01

Experimental studies of the positron annihilation induced Auger electron (PAES) spectra from the Fe-Cu alloy surfaces with quantum-dot like Cu nanoparticles embedded in Fe show that the PAES signal from Cu increase rapidly as the concentration of Cu is enhanced by vacuum annealing. These measurements indicate that almost 75% of positrons that annihilate with core electrons due so with Cu even though the surface concentration of Cu as measured by EAES is only 6%. This result suggests that positrons become localized at sites at the surface containing high concentration of Cu atoms before annihilation. These experimental results are investigated theoretically by performing calculations of the "image-potential" positron surface states and annihilation characteristics of the surface trapped positrons with relevant Fe and Cu core-level electrons for the clean Fe(100) and Cu(100) surfaces and for the Fe(100) surface with quantum-dot like Cu nanoparticles embedded in the top atomic layers of the host substrate. Estimates of the positron binding energy and positron annihilation characteristics reveal their strong sensitivity to the nanoparticle coverage. Computed core annihilation probabilities are compared with experimental ones estimated from the measured Auger peak intensities. The observed behavior of the Fe and Cu PAES signal intensities is explained by theoretical calculations as being due to trapping of positrons in the regions of Cu nanoparticles embedded in the top atomic layers of Fe.

Electron emission from surfaces resulting from low energy positron bombardment

NASA Astrophysics Data System (ADS)

Mukherjee, Saurabh

Measurements of the secondary electron energy spectra resulting from very low energy positron bombardment of a polycrystalline Au and Cu (100) surfaces are presented that provide evidence for a single step transition from an unbound scattering state to an image potential bound state. The primary positron energy threshold for secondary electron emission and energy cutoff of the positron induced secondary electron energy peak are consistent with an Auger like process in which an incident positron make a transition from a scattering state to a surface-image potential bound while transferring all of the energy difference to an outgoing secondary electron. We term this process: the Auger mediated quantum sticking effect (AQSE). The intensities of the positron induced secondary electron peak are used to estimate the probability of this process as a function of incident positron energy. Positron annihilation induced Auger spectra (PAES) of Cu and Au are presented that are free of all primary beam induced secondary electron background. This background was eliminated by setting the positron beam energy below AQSE threshold. The background free PAES spectra obtained include the first measurements of the low energy tail of CVV Auger transitions all the way down to zero kinetic energy. The integrated intensity of this tail is several times larger than Auger peak itself which provides strong evidence for multi-electron Auger processes.

Spectra of electrons emitted as a result of the sticking and annihilation of low energy positrons to the surfaces of graphene and highly oriented pyrolytic graphite (HOPG)

NASA Astrophysics Data System (ADS)

Chrysler, M.; Chirayath, V.; McDonald, A.; Lim, Z.; Shastry, K.; Gladen, R.; Fairchild, A.; Koymen, A.; Weiss, A.

Positron annihilation induced Auger electron spectroscopy (PAES) was used to study the positron induced low energy electron spectra from HOPG and a sample composed of 6-8 layers of graphene grown on polycrystalline copper. A low energy (~2eV) beam of positrons was used to implant positrons into a surface localized state on the graphene and HOPG samples. Measurements of the energy spectra of the positron induced electrons obtained using a TOF spectrometer indicate the presence of an annihilation induced KLL C Auger peak (at ~263 eV) along with a narrow low energy secondary peak due to an Auger mediated positron sticking (AMPS) process. A broad spectral feature was also observed below ~15 eV which we believe may be due to a VVV C Auger transition not previously observed. The energy dependence of the integrated intensity of the AMPS peak was measured for a series of incident positron kinetic energies ranging from ~1.5 eV up to 11 eV from which the binding energy of the surface localized positron state on graphene and HOPG was estimated. The implication of our results regarding the applicability of AMPS and PAES to the study of graphene surfaces and interfaces will be discussed. This work was supported by NSF Grant No. DMR 1508719 and DMR 1338130.

Nonlinear excitations for the positron acoustic shock waves in dissipative nonextensive electron-positron-ion plasmas

NASA Astrophysics Data System (ADS)

Saha, Asit

2017-03-01

Positron acoustic shock waves (PASHWs) in unmagnetized electron-positron-ion (e-p-i) plasmas consisting of mobile cold positrons, immobile positive ions, q-nonextensive distributed electrons, and hot positrons are studied. The cold positron kinematic viscosity is considered and the reductive perturbation technique is used to derive the Burgers equation. Applying traveling wave transformation, the Burgers equation is transformed to a one dimensional dynamical system. All possible vector fields corresponding to the dynamical system are presented. We have analyzed the dynamical system with the help of potential energy, which helps to identify the stability and instability of the equilibrium points. It is found that the viscous force acting on cold mobile positron fluid is a source of dissipation and is responsible for the formation of the PASHWs. Furthermore, fully nonlinear arbitrary amplitude positron acoustic waves are also studied applying the theory of planar dynamical systems. It is also observed that the fundamental features of the small amplitude and arbitrary amplitude PASHWs are significantly affected by the effect of the physical parameters q e , q h , μ e , μ h , σ , η , and U. This work can be useful to understand the qualitative changes in the dynamics of nonlinear small amplitude and fully nonlinear arbitrary amplitude PASHWs in solar wind, ionosphere, lower part of magnetosphere, and auroral acceleration regions.

Convergent evolution of modularity in metabolic networks through different community structures

PubMed Central

2012-01-01

Background It has been reported that the modularity of metabolic networks of bacteria is closely related to the variability of their living habitats. However, given the dependency of the modularity score on the community structure, it remains unknown whether organisms achieve certain modularity via similar or different community structures. Results In this work, we studied the relationship between similarities in modularity scores and similarities in community structures of the metabolic networks of 1021 species. Both similarities are then compared against the genetic distances. We revisited the association between modularity and variability of the microbial living environments and extended the analysis to other aspects of their life style such as temperature and oxygen requirements. We also tested both topological and biological intuition of the community structures identified and investigated the extent of their conservation with respect to the taxomony. Conclusions We find that similar modularities are realized by different community structures. We find that such convergent evolution of modularity is closely associated with the number of (distinct) enzymes in the organism’s metabolome, a consequence of different life styles of the species. We find that the order of modularity is the same as the order of the number of the enzymes under the classification based on the temperature preference but not on the oxygen requirement. Besides, inspection of modularity-based communities reveals that these communities are graph-theoretically meaningful yet not reflective of specific biological functions. From an evolutionary perspective, we find that the community structures are conserved only at the level of kingdoms. Our results call for more investigation into the interplay between evolution and modularity: how evolution shapes modularity, and how modularity affects evolution (mainly in terms of fitness and evolvability). Further, our results call for exploring new measures of modularity and network communities that better correspond to functional categorizations. PMID:22974099

Positron-rubidium scattering

NASA Technical Reports Server (NTRS)

Mceachran, R. P.; Horbatsch, M.; Stauffer, A. D.

1990-01-01

A 5-state close-coupling calculation (5s-5p-4d-6s-6p) was carried out for positron-Rb scattering in the energy range 3.7 to 28.0 eV. In contrast to the results of similar close-coupling calculations for positron-Na and positron-K scattering the (effective) total integrated cross section has an energy dependence which is contrary to recent experimental measurements.

Physics perspectives at JLab with a polarized positron beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voutier, Eric J.-M.

2014-06-01

Polarized positron beams are in some respect mandatory complements to polarized electron beams. The advent of the PEPPo concept for polarized positron production opens the possibility for the developement at the Jefferson Laboratory of a continuous polarized positron beam. The benefits of such a beam for hadronic structure studies are discussed, together with the technical and technological challenges to face.

A study of the effects of strong magnetic fields on the image resolution of PET scanners

NASA Astrophysics Data System (ADS)

Burdette, Don J.

Very high resolution images can be achieved in small animal PET systems utilizing solid state silicon pad detectors. In such systems using detectors with sub-millimeter intrinsic resolutions, the range of the positron is the largest contribution to the image blur. The size of the positron range effect depends on the initial positron energy and hence the radioactive tracer used. For higher energy positron emitters, such as 68Ga and 94mTc, the variation of the annihilation point dominates the spatial resolution. In this study two techniques are investigated to improve the image resolution of PET scanners limited by the range of the positron. One, the positron range can be reduced by embedding the PET field of view in a strong magnetic field. We have developed a silicon pad detector based PET instrument that can operate in strong magnetic fields with an image resolution of 0.7 mm FWHM to study this effect. Two, iterative reconstruction methods can be used to statistically correct for the range of the positron. Both strong magnetic fields and iterative reconstruction algorithms that statistically account for the positron range distribution are investigated in this work.

High-temperature studies of grain boundaries in ultrafine grained alloys by means of positron lifetime

NASA Astrophysics Data System (ADS)

Würschum, R.; Shapiro, E.; Dittmar, R.; Schaefer, H.-E.

2000-11-01

Atomic free volumes and vacancies in the ultrafine grained alloys Pd84Zr16, Cu 0.1 wt % ZrO2, and Fe91Zr9 were studied by means of positron lifetime. The thermally stable microstructures serve as a novel type of model system for studying positron trapping and annihilation as well as the thermal behavior of vacancy-sized free volumes over a wide temperature range up to ca. 1200 K by making use of a metallic 58Co positron source. In ultrafine grained Cu the thermal formation of lattice vacancies could be observed. In Pd84Zr16 an increase of the specific positron trapping rate of nanovoids and, in addition, detrapping of positrons from free volumes with a mean size slightly smaller than one missing atom in the grain boundaries contributes to a reversible increase of the positron lifetime of more than 60 ps with measuring temperature. In Fe91Zr9 similar linear high-temperature increases of the positron lifetime are observed in the nanocrystalline and the amorphous state. The question of thermal vacancy formation in grain boundaries is addressed taking into account the different types of interface structures of the present alloys.

Study of positron annihilation with core electrons at the clean and oxygen covered Ag(001) surface

NASA Astrophysics Data System (ADS)

Joglekar, P.; Shastry, K.; Olenga, A.; Fazleev, N. G.; Weiss, A. H.

2013-03-01

In this paper we present measurements of the energy spectrum of electrons emitted as a result of Positron Annihilation Induce Auger Electron Emission from a clean and oxygen covered Ag (100) surface using a series of incident beam energies ranging from 20 eV down to 2 eV. A peak was observed at ~ 40 eV corresponding to the N23VV Auger transition in agreement with previous PAES studies. Experimental results were investigated theoretically by calculations of positron states and annihilation probabilities of surface-trapped positrons with relevant core electrons at the clean and oxygen covered Ag(100) surface. An ab-initio investigation of stability and associated electronic properties of different adsorption phases of oxygen on Ag(100) has been performed on the basis of density functional theory and using DMOl3 code. The computed positron binding energy, positron surface state wave function, and positron annihilation probabilities of surface trapped positrons with relevant core electrons demonstrate their sensitivity to oxygen coverage, elemental content, atomic structure of the topmost layers of surfaces, and charge transfer effects. Theoretical results are compared with experimental data. This work was supported in part by the National Science Foundation Grant # DMR-0907679.

Probing the defects in nano-semiconductors using positrons

NASA Astrophysics Data System (ADS)

Nambissan, P. M. G.

2011-01-01

Positron annihilation spectroscopy (PAS) is a very useful tool to study the defect properties of nanoscale materials. The ability of thermalized positrons to diffuse over to the surfaces of nanocrystallites prior to annihilation helps to explore the disordered atomic arrangement over there and is very useful in understanding the structure and properties of nanomaterials. As examples, the results of studies on FeS2 nanorods and ZnS nanoparticles are presented. In semiconductor nanoparticles, there are positron trapping sites within the grains also and these are characterised by using appropriate models on the measured positron lifetimes. We have observed vivid changes in the measured positron lifetimes and Doppler broadened gamma ray spectral lineshapes during structural transformations prompted by substitutional effects in Mn2+-doped ZnS nanorods. Interestingly, the nanoparticles did not exhibit the transformation, implying the morphologies of the nanosystems playing a decisive role. Quantum confinement effect in CdS nanoparticles was another phenomenon that could be seen through positron annihilation experiments. Coincidence Doppler broadening measurements have been useful to identify the elemental environment around the vacancy clusters that trap positrons. Recent studies on nanocrystalline oxide and sulphide semiconductors are also discussed.

Opportunities and challenges of a low-energy positron source in the LERF

NASA Astrophysics Data System (ADS)

Benson, Stephen; Wojtsekhowski, Bogdan; Vlahovic, Branislav; Golge, Serkan

2018-05-01

Though there are many applications of low energy positrons, many experiments are source limited. Using the LERF accelerator at the Thomas Jefferson National Accelerator Facility, it is possible to build a high brightness source of very low-energy positrons. The accelerator requirements are well within the capabilities of the installed hardware. The accelerator can produce 120 kW of beam with a beam energy of up to 170 MeV. For these experiments, we only need run at up to 120 MeV. The gamma-to-positron converter must be able to absorb 20% of the beam power that the linac delivers. At this low an energy the converter, though challenging, is possible. The transport of the low energy positrons from the production target to the next stage, where the energy is reduced even further, must have a very large acceptance to be able to efficiently transport the flux of positrons from the positron production target to the moderator. We propose to accomplish such a transport by means of a guiding solenoidal field with a novel endcap design. In this presentation, we will present the proposed schemes necessary to realize such a high brightness positron source.

Free-volume characterization of nanostructurized substances by positron annihilation lifetime spectroscopy

NASA Astrophysics Data System (ADS)

Shpotyuk, O.; Ingram, A.; Shpotyuk, Ya.

2018-02-01

Methodological possibilities of positron annihilation lifetime (PAL) spectroscopy are examined to parameterize free-volume structural evolution processes in some nanostructurized substances obeying conversion from positronium (Ps) decaying to positron trapping. Unlike conventional x3-term fitting analysis based on admixed positron trapping and Ps decaying, the effect of nanostructurization is considered as occurring due to conversion from preferential Ps decaying in initial host matrix to positron trapping in modified (nanostructurized) host-guest matrix. The developed approach referred to as x3-x2-CDA (coupling decomposition algorithm) allows estimation defect-free bulk and defect-specific positron lifetimes of free-volume elements responsible for nanostructurization. The applicability of this approach is proved for some nanostructurized materials allowing free-volume changes through Ps-to-positron trapping conversion, such as (i) metallic Ag nanoparticles embedded in polymer matrix, (ii) structure-modification processes caused by swift heavy ions irradiation in polystyrene, and (iii) host-guest chemistry problems like water immersion in alumomagnesium spinel ceramics. This approach is considered to be used as test-indicator, separating processes of host-matrix nanostructurization due to embedded nanoparticles from uncorrelated changes in positron-trapping and Ps-decaying channels.

Present status of the low energy linac-based slow positron beam and positronium spectrometer in Saclay

NASA Astrophysics Data System (ADS)

Liszkay, L.; Comini, P.; Corbel, C.; Debu, P.; Grandemange, P.; Pérez, P.; Rey, J.-M.; Reymond, J.-M.; Ruiz, N.; Sacquin, Y.; Vallage, B.

2014-04-01

A new slow positron beamline featuring a large acceptance positronium lifetime spectrometer has been constructed and tested at the linac-based slow positron source at IRFU CEA Saclay, France. The new instrument will be used in the development of a dense positronium target cloud for the GBAR experiment. The GBAR project aims at precise measurement of the gravitational acceleration of antihydrogen in the gravitational field of the Earth. Beyond application in fundamental science, the positron spectrometer will be used in materials research, for testing thin porous films and layers by means of positronium annihilation. The slow positron beamline is being used as a test bench to develop further instrumentation for positron annihilation spectroscopy (Ps time-of-flight, pulsed positron beam). The positron source is built on a low energy linear electron accelerator (linac). The 4.3 MeV electron energy used is well below the photoneutron threshold, making the source a genuine on-off device, without remaining radioactivity. The spectrometer features large BGO (Bismuth Germanate) scintillator detectors, with sufficiently large acceptance to detect all ortho-positronium annihilation lifetime components (annihilation in vacuum and in nanopores).

Modular jet impingement assemblies with passive and active flow control for electronics cooling

DOEpatents

Zhou, Feng; Dede, Ercan Mehmet; Joshi, Shailesh

2016-09-13

Power electronics modules having modular jet impingement assembly utilized to cool heat generating devices are disclosed. The modular jet impingement assemblies include a modular manifold having a distribution recess, one or more angled inlet connection tubes positioned at an inlet end of the modular manifold that fluidly couple the inlet tube to the distribution recess and one or more outlet connection tubes positioned at an outlet end of the modular manifold that fluidly coupling the outlet tube to the distribution recess. The modular jet impingement assemblies include a manifold insert removably positioned within the distribution recess and include one or more inlet branch channels each including an impinging slot and one or more outlet branch channels each including a collecting slot. Further a heat transfer plate coupled to the modular manifold, the heat transfer plate comprising an impingement surface including an array of fins that extend toward the manifold insert.

Modular cathode assemblies and methods of using the same for electrochemical reduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiedmeyer, Stanley G.; Barnes, Laurel A.; Williamson, Mark A.

Modular cathode assemblies are useable in electrolytic reduction systems and include a basket through which fluid electrolyte may pass and exchange charge with a material to be reduced in the basket. The basket can be divided into upper and lower sections to provide entry for the material. Example embodiment cathode assemblies may have any shape to permit modular placement at any position in reduction systems. Modular cathode assemblies include a cathode plate in the basket, to which unique and opposite electrical power may be supplied. Example embodiment modular cathode assemblies may have standardized electrical connectors. Modular cathode assemblies may bemore » supported by a top plate of an electrolytic reduction system. Electrolytic oxide reduction systems are operated by positioning modular cathode and anode assemblies at desired positions, placing a material in the basket, and charging the modular assemblies to reduce the metal oxide.« less

Modular cathode assemblies and methods of using the same for electrochemical reduction

DOEpatents

Wiedmeyer, Stanley G; Barnes, Laurel A; Williamson, Mark A; Willit, James L

2014-12-02

Modular cathode assemblies are useable in electrolytic reduction systems and include a basket through which fluid electrolyte may pass and exchange charge with a material to be reduced in the basket. The basket can be divided into upper and lower sections to provide entry for the material. Example embodiment cathode assemblies may have any shape to permit modular placement at any position in reduction systems. Modular cathode assemblies include a cathode plate in the basket, to which unique and opposite electrical power may be supplied. Example embodiment modular cathode assemblies may have standardized electrical connectors. Modular cathode assemblies may be supported by a top plate of an electrolytic reduction system. Electrolytic oxide reduction systems are operated by positioning modular cathode and anode assemblies at desired positions, placing a material in the basket, and charging the modular assemblies to reduce the metal oxide.

Studies of high coverage oxidation of the Cu(100) surface using low energy positrons

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Maddox, W. B.; Weiss, A. H.

2012-02-01

The study of oxidation of single crystal metal surfaces is important in understanding the corrosive and catalytic processes associated with thin film metal oxides. The structures formed on oxidized transition metal surfaces vary from simple adlayers of chemisorbed oxygen to more complex structures which result from the diffusion of oxygen into subsurface regions. In this work we present the results of theoretical studies of positron surface and bulk states and annihilation probabilities of surface-trapped positrons with relevant core electrons at the oxidized Cu(100) surface under conditions of high oxygen coverage. Calculations are performed for various high coverage missing row structures ranging between 0.50 and 1.50 ML oxygen coverage. The results of calculations of positron binding energy, positron work function, and annihilation characteristics of surface trapped positrons with relevant core electrons as function of oxygen coverage are compared with experimental data obtained from studies of oxidation of the Cu(100) surface using positron annihilation induced Auger electron spectroscopy (PAES).

Theoretical aspects of studies of oxide and semiconductor surfaces using low energy positrons

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Maddox, W. B.; Weiss, A. H.

2011-01-01

This paper presents the results of a theoretical study of positron surface and bulk states and annihilation characteristics of surface trapped positrons at the oxidized Cu(100) single crystal and at both As- and Ga-rich reconstructed GaAs(100) surfaces. The variations in atomic structure and chemical composition of the topmost layers of the surfaces associated with oxidation and reconstructions and the charge redistribution at the surfaces are found to affect localization and spatial extent of the positron surface-state wave functions. The computed positron binding energy, work function, and annihilation characteristics reveal their sensitivity to charge transfer effects, atomic structure and chemical composition of the topmost layers of the surfaces. Theoretical positron annihilation probabilities with relevant core electrons computed for the oxidized Cu(100) surface and the As- and Ga-rich reconstructed GaAs(100) surfaces are compared with experimental ones estimated from the positron annihilation induced Auger peak intensities measured from these surfaces.

Efficient and surface site-selective ion desorption by positron annihilation.

PubMed

Tachibana, Takayuki; Yamashita, Takashi; Nagira, Masaru; Yabuki, Hisakuni; Nagashima, Yasuyuki

2018-05-08

We compared positron- and electron-stimulated desorption (e + SD and ESD) of positive ions from a TiO 2 (110) surface. Although desorption of O + ions was observed in both experiments, the desorption efficiency caused by positron bombardment was larger by one order of magnitude than that caused by electron bombardment at an incident energy of 500 eV. e + SD of O + ions remained highly efficient with incident positron energies between 10 eV and 600 eV. The results indicate that e + SD of O + ions is predominantly caused by pair annihilation of surface-trapped positrons with inner-shell electrons. We also tested e + SD from water chemisorbed on the TiO 2 surface and found that the desorption of specific ions was enhanced by positron annihilation, above the ion yield with electron bombardment. This finding corroborates our conclusion that annihilation-site selectivity of positrons results in site-selective ion desorption from a bombarded surface.

Free Volume Structure of Acrylic-Type Dental Nanocomposites Tested with Annihilating Positrons.

PubMed

Shpotyuk, Olha; Ingram, Adam; Shpotyuk, Oleh

2016-12-01

Positron annihilation spectroscopy in lifetime measuring mode exploring conventional fast-fast coincidence ORTEC system is employed to characterize free volume structure of commercially available acrylic-type dental restorative composite Charisma® (Heraeus Kulzer GmbH, Germany). The measured lifetime spectra for uncured and light-cured composites are reconstructed from unconstrained x3-term fitting and semi-empirical model exploring x3-x2-coupling decomposition algorithm. The governing channel of positron annihilation in the composites studied is ascribed to mixed positron-Ps trapping, where Ps decaying in the third component is caused entirely by input from free-volume holes in polymer matrix, while the second component is defined by free positron trapping in interfacial free-volume holes between filler nanoparticles and surrounded polymer matrix. Microstructure scenario of the photopolymerization shrinkage includes cross-linking of structural chains in polymer matrix followed by conversion of bound positron-electron (positronium) traps in positron-trapping interfacial free-volume voids in a vicinity of agglomerated filler nanoparticles.

Dipole configuration for confinement of positrons and electron-positron plasma

NASA Astrophysics Data System (ADS)

Stenson, E. V.; Saitoh, H.; Horn-Stanja, J.; Hergenhahn, U.; Paschkowski, N.; Sunn Pedersen, T.; Stoneking, M. R.; Dickmann, M.; Singer, M.; Vohburger, S.; Hugenschmidt, C.; Schweikhard, L.; Danielson, J. R.; Surko, C. M.

2016-10-01

Laboratory creation and confinement of electron-positron plasmas, which are expected to exhibit atypical plasma physics characteristics, would enable tests of many theory and simulation predictions (e.g., the stabilization of anomalous transport mechanisms). This is the goal of APEX/PAX (A Positron-Electron eXperiment/Positron Accumulation eXperiment). Following demonstration of efficient (38%) E ×B injection and subsequent confinement (τ = 3-5 ms) of cold positrons in a dipole magnetic field, the system is undergoing upgrades from a supported permanent magnet to a supported HTSC (high-temperature superconductor) coil, then to a levitated HTSC coil suitable for the simultaneous confinement of electrons and positrons. This contribution will report on the design and testing of the new systems and subsystems (e.g., for cooling, excitation, and levitation) and, if available, on results of upcoming experiments using a ``rotating wall'' to generate inward particle flux deeper into the confinement region. on behalf of the APEX/PAX team and collaborators.

Chaos of energetic positron orbits in a dipole magnetic field and its potential application to a new injection scheme

NASA Astrophysics Data System (ADS)

Saitoh, H.; Yoshida, Z.; Yano, Y.; Nishiura, M.; Kawazura, Y.; Horn-Stanja, J.; Pedersen, T. Sunn

2016-10-01

We study the behavior of high-energy positrons emitted from a radioactive source in a magnetospheric dipole field configuration. Because the conservation of the first and second adiabatic invariants is easily destroyed in a strongly inhomogeneous dipole field for high-energy charged particles, the positron orbits are nonintegrable, resulting in chaotic motions. In the geometry of a typical magnetospheric levitated dipole experiment, it is shown that a considerable ratio of positrons from a 22Na source, located at the edge of the confinement region, has chaotic long orbit lengths before annihilation. These particles make multiple toroidal circulations and form a hollow toroidal positron cloud. Experiments with a small 22Na source in the Ring Trap 1 (RT-1) device demonstrated the existence of such long-lived positrons in a dipole field. Such a chaotic behavior of high-energy particles is potentially applicable to the formation of a dense toroidal positron cloud in the strong-field region of the dipole field in future studies.

Positron annihilation spectroscopic studies of solvothermally synthesized ZnO nanobipyramids and nanoparticles

NASA Astrophysics Data System (ADS)

Ghoshal, Tandra; Biswas, Subhajit; Kar, Soumitra; Chaudhuri, Subhadra; Nambissan, P. M. G.

2008-02-01

Zinc oxide (ZnO) samples in the form of hexagonal-based bipyramids and particles of nanometer dimensions were synthesized through solvothermal route and characterized by x-ray diffraction and transmission electron microscopy. Positron annihilation experiments were performed to study the structural defects such as vacancies and surfaces in these nanosystems. From coincidence Doppler broadening measurements, the positron trapping sites were identified as Zn vacancies or Zn-O-Zn trivacancy clusters. The positron lifetimes, their relative intensities, and the Doppler broadened lineshape parameter S all showed characteristic changes across the nanobipyramid size corresponding to the thermal diffusion length of positrons. In large nanobipyramids, vacancies within the crystallites also trapped positrons and the effects of agglomeration of such vacancies due to increased temperatures of synthesis were reflected in the variation of the annihilation parameters with their base diameters. The sizes of the nanoparticles used were all in the limit of thermal diffusion length of positrons and the annihilation characteristics were in accordance with the decreasing contribution from surfaces with increasing particle size.

Positron annihilation spectroscopic studies of solvothermally synthesized ZnO nanobipyramids and nanoparticles.

PubMed

Ghoshal, Tandra; Biswas, Subhajit; Kar, Soumitra; Chaudhuri, Subhadra; Nambissan, P M G

2008-02-21

Zinc oxide (ZnO) samples in the form of hexagonal-based bipyramids and particles of nanometer dimensions were synthesized through solvothermal route and characterized by x-ray diffraction and transmission electron microscopy. Positron annihilation experiments were performed to study the structural defects such as vacancies and surfaces in these nanosystems. From coincidence Doppler broadening measurements, the positron trapping sites were identified as Zn vacancies or Zn-O-Zn trivacancy clusters. The positron lifetimes, their relative intensities, and the Doppler broadened lineshape parameter S all showed characteristic changes across the nanobipyramid size corresponding to the thermal diffusion length of positrons. In large nanobipyramids, vacancies within the crystallites also trapped positrons and the effects of agglomeration of such vacancies due to increased temperatures of synthesis were reflected in the variation of the annihilation parameters with their base diameters. The sizes of the nanoparticles used were all in the limit of thermal diffusion length of positrons and the annihilation characteristics were in accordance with the decreasing contribution from surfaces with increasing particle size.

Studies of Oxidation of the Cu(100) Surface Using Low Energy Positrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fazleev, N. G.; Kazan State University, Kazan 420008; Maddox, W. B.

2009-03-10

Changes in the surface of an oxidized Cu(100) single crystal resulting from vacuum annealing have been investigated using positron annihilation induced Auger electron spectroscopy (PAES). PAES measurements show a large increase in the intensity of the positron annihilation induced Cu M{sub 2,3}VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300 deg. C. The intensity then decreases monotonically as the annealing temperature is increased to {approx}600 deg. C. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant coremore » electrons taking into account the charge redistribution at the surface, surface reconstructions, and electron-positron correlations effects. Possible explanation for the observed behavior of the intensity of positron annihilation induced Cu M{sub 2,3}VV Auger peak with changes of the annealing temperature is proposed.« less

Development of a Simple Positron Age-Momentum Setup

NASA Astrophysics Data System (ADS)

Sheffield, Thomas; Quarles, C. A.

2009-04-01

A positron age-momentum setup that uses NIM Bin electronic modules and a conventional multichannel analyzer (MCA) is described. The essential idea is to accumulate a Doppler broadened spectrum (sensitive to the annihilation electron momentum) using a high purity Germanium detector in coincidence with a BaF2 scintillation counter, which also serves as the stop signal in a conventional positron lifetime setup. The MCA that collects the Doppler spectrum is gated by a selected region of the lifetime spectrum. Thus we can obtain Doppler broadening spectra as a function of positron lifetime: an age-momentum spectrum. The apparatus has been used so far to investigate a ZnO sample where the size of different vacancy trapping sites may affect the positron lifetime and the Doppler broadening spectrum. We are also looking at polymer and rubber carbon-black composite samples where differences in the Doppler spectrum may arise from positron trapping or positronium formation in the samples. Correction for background and contribution from the positron source itself to the Doppler spectrum will be discussed.

Positronium formation in SiO2 films grown on Si substrates studied by monoenergetic positron beams

NASA Astrophysics Data System (ADS)

Uedono, A.; Wei, L.; Tanigawa, S.; Suzuki, R.; Ohgaki, H.; Mikado, T.; Kawano, T.; Ohji, Y.

1994-04-01

The annihilation characteristics of positrons in SiO2 films grown on Si substrates were studied by using monoenergetic positron beams. Doppler broadening profiles of the annihilation radiation and lifetime spectra of positrons were measured as a function of incident positron energy for SiO2 (166 nm)/Si specimens fabricated by thermal oxidation. From the measurements, it was found that about 90% of positrons implanted into the SiO2 film annihilate from positronium (Ps) states. This fact was due to the trapping of positrons by open-space defects and a resultant enhanced formation of Ps in such regions. For the SiO2 film grown at 650 °C, the lifetime of ortho-Ps was found to be shorter than that in the film grown at 1000 °C. This result suggests that the volume of open-space defects in the SiO2 film decreased with decreasing the growth rate of the SiO2 film.

An overview of Laser-Produced Relativistic Positrons in the Laboratory

NASA Astrophysics Data System (ADS)

Edghill, Brandon; Williams, Gerald; Chen, Hui; Beg, Farhat

2017-10-01

The production of relativistic positrons using ultraintense lasers can facilitate studies of fundamental pair plasma science in the relativistic regime and laboratory studies of scaled energetic astrophysical mechanisms such as gamma ray bursts. The positron densities and spatial scales required for these applications, however, are larger than current capabilities. Here, we present an overview of the experimental laser-produced positron results and their respective modeling for both the direct laser-irradiated process and the indirect process (laser wakefield accelerated electrons irradiating a high-Z converter). Conversion efficiency into positrons and positron beam characteristics are compared, including total pair yield, mean energy, angular divergence, and inferred pair density for various laser and target conditions. Prospects towards increasing positron densities and beam repetition rates will also be discussed. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344, and funded by LDRD (#17-ERD-010).

Development of a Slow Positron Facility at Hebrew University of Jerusalem

NASA Astrophysics Data System (ADS)

Kelleher, Aidan

2013-03-01

Positron annihilation spectroscopy provides both depth of penetration to study bulk defects in materials as well as nano-scale resolution. This measurement range is achieved by slowing positrons from a radioactive source, typically 22Na, by sending them through a moderator, typically W or solid Ne. The nearly thermal positrons are then accelerated to the desired energy by means of an electrostatic potential. The SPOT project at The Hebrew University of Jerusalem proposes to increase the luminosity of the beam by applying the best practices currently in us, as well as using a short-lived source of positrons, 18F. Simulations based on our current designs indicate this project will be able to deliver positrons in the energy range of 50-50000eV with an energy resolution of 1eV is possible. We will present the unique technical challenges of using this source of positrons, how we plan to overcome them, the results of simulations, and facility construction progress.

The Current Status of Modular Coordination. A Research Correlation Conference of Building Research Institute, Division of Engineering and Industrial Research (Fall 1959).

ERIC Educational Resources Information Center

National Academy of Sciences - National Research Council, Washington, DC.

Publication of conference presentations include--(1) a brief review of current modular standard development, (2) the statistical status of modular practice, (3) availability of modular products, and (4) educational programs on modular coordination. Included are--(1) explanatory diagrams, (2) text of an open panel discussion, and (3) a list of…

Quantum chemical approach for positron annihilation spectra of atoms and molecules beyond plane-wave approximation

NASA Astrophysics Data System (ADS)

Ikabata, Yasuhiro; Aiba, Risa; Iwanade, Toru; Nishizawa, Hiroaki; Wang, Feng; Nakai, Hiromi

2018-05-01

We report theoretical calculations of positron-electron annihilation spectra of noble gas atoms and small molecules using the nuclear orbital plus molecular orbital method. Instead of a nuclear wavefunction, the positronic wavefunction is obtained as the solution of the coupled Hartree-Fock or Kohn-Sham equation for a positron and the electrons. The molecular field is included in the positronic Fock operator, which allows an appropriate treatment of the positron-molecule repulsion. The present treatment succeeds in reproducing the Doppler shift, i.e., full width at half maximum (FWHM) of experimentally measured annihilation (γ-ray) spectra for molecules with a mean absolute error less than 10%. The numerical results indicate that the interpretation of the FWHM in terms of a specific molecular orbital is not appropriate.

Slow positrons in the study of surface and near-surface defects

NASA Astrophysics Data System (ADS)

Lynn, K. G.

A general theoretical model is presented which includes the probability of a positron diffusing back to the surface after implantation, and thermalization in samples containing various defects. This model incorporates surface state and thermal desorption from this state, as well as reflection back into the bulk. With this model vacancy formation enthalpies, activation energies of positrons from surface states, and specific trapping rates are deduced from the positronium fraction data. An amorphous Al/sub x/O/sub y/ overlayer on Al is discussed as an example of trapping in overlayers. In well-annealed single crystal samples, the positron is shown to be freely diffusing at low temperatures, whereas in a neutron-irradiatied Al single crystal sample the positron is localized at low positron binding energy defects presumably created during irradiation.

Advanced characterization of lithium battery materials with positrons

NASA Astrophysics Data System (ADS)

Barbiellini, Bernardo; Kuriplach, Jan

2017-01-01

Cathode materials are crucial to improved battery performance, in part because there are not yet materials that can maintain high power and stable cycling with a capacity comparable to that of anode materials. Our parameter-free, gradient-corrected model for electron-positron correlations predicts that spectroscopies based on positron annihilation can be deployed to study the effect of lithium intercalation in the oxide matrix of the cathode. The positron characteristics in oxides can be reliably computed using methods based on first-principles. Thus, we can enable a fundamental characterization of lithium battery materials involving positron annihilation spectroscopy and first-principles calculations. The detailed information one can extract from positron experiments could be useful for understanding and optimizing both battery materials and bi-functional catalysts for oxygen reduction and evolution.

Positrons as interface-sensitive probes of polar semiconductor heterostructures

NASA Astrophysics Data System (ADS)

Makkonen, I.; Snicker, A.; Puska, M. J.; Mäki, J.-M.; Tuomisto, F.

2010-07-01

Group-III nitrides in their wurtzite crystal structure are characterized by large spontaneous polarization and significant piezoelectric contributions in heterostructures formed of these materials. Polarization discontinuities in polar heterostructures grown along the (0001) direction result in huge built-in electric fields on the order of megavolt per centimeter. We choose the III-nitride heterostructures as archetypal representatives of polar heterostructures formed of semiconducting or insulating materials and study the behavior of positrons in these structures using first-principles electronic-structure theory supported by positron annihilation experiments for bulk systems. The strong electric fields drive positrons close to interfaces, which is clearly seen in the predicted momentum distributions of annihilating electron-positron pairs as changes relative to the constituent bulk materials. Implications of the effect to positron defect studies of polar heterostructures are addressed.

Observation of interface defects in thermally oxidized SiC using positron annihilation

NASA Astrophysics Data System (ADS)

Dekker, James; Saarinen, Kimmo; Ólafsson, Halldór; Sveinbjörnsson, Einar Ö.

2003-03-01

Positron annihilation has been applied to study thermally oxidized 4H- and 6H-SiC. The SiC/SiO2 interface is found to contain a high density of open-volume defects. The positron trapping at the interface defects correlates with the charge of the interface determined by capacitance-voltage experiments. For oxides grown on n-SiC substrates, the positron annihilation characteristics at these defects are nearly indistinguishable from those of a silicon/oxide interface, with no discernable contribution from C-related bonds or carbon clusters. These results indicate that those defects at the SiC/oxide interface, which are visible to positrons, are similar to those at the Si/oxide interface. The positron annihilation characteristics suggest that these defects are vacancies surrounded by oxygen atoms.

Ultrashort megaelectronvolt positron beam generation based on laser-accelerated electrons

NASA Astrophysics Data System (ADS)

Xu, Tongjun; Shen, Baifei; Xu, Jiancai; Li, Shun; Yu, Yong; Li, Jinfeng; Lu, Xiaoming; Wang, Cheng; Wang, Xinliang; Liang, Xiaoyan; Leng, Yuxin; Li, Ruxin; Xu, Zhizhan

2016-03-01

Experimental generation of ultrashort MeV positron beams with high intensity and high density using a compact laser-driven setup is reported. A high-density gas jet is employed experimentally to generate MeV electrons with high charge; thus, a charge-neutralized MeV positron beam with high density is obtained during laser-accelerated electrons irradiating high-Z solid targets. It is a novel electron-positron source for the study of laboratory astrophysics. Meanwhile, the MeV positron beam is pulsed with an ultrashort duration of tens of femtoseconds and has a high peak intensity of 7.8 × 1021 s-1, thus allows specific studies of fast kinetics in millimeter-thick materials with a high time resolution and exhibits potential for applications in positron annihilation spectroscopy.

Possible detection of flare-generated positrons by Helios 1 on 3 Jun 1982

NASA Technical Reports Server (NTRS)

Kirsch, E.; Keppler, E.; Richter, K.

1985-01-01

The production of neutrons and gamma-ray lines by solar particles in the photosphere has been studied. The principal positron emiters which lead to the 0.51 MeV gamma-line are C-11 0-14, 0-15, N-13, Ne-19. The energies of the positrons form radioactive nuclei are of the order of few hundred keV. Positrons resulting from the pi(+) decay have energies of approx 10-100 MeV and cannot be measured by the MPAe-detector. Most of the positrons annihilate in the photosphere. A fraction however should be able to escape into the interplanetary space. Proton, electron and , for the first time, positron measurements (E = 152-546 keV) obtained by the MPAe-particle detector on board of Helios 1 are presented.

Modular Design in Treaty Verification Equipment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Macarthur, Duncan Whittemore; Benz, Jacob; Tolk, Keith

2015-01-27

It is widely believed that modular design is a good thing. However, there are often few explicit arguments, or even an agreed range of definitions, to back up this belief. In this paper, we examine the potential range of design modularity, the implications of various amounts of modularity, and the advantages and disadvantages of each level of modular construction. We conclude with a comparison of the advantages and disadvantages of each type, as well as discuss many caveats that should be observed to take advantage of the positive features of modularity and minimize the effects of the negative. The tradeoffsmore » described in this paper will be evaluated during the conceptual design to determine what amount of modularity should be included.« less

A positron remoderator for the high intensity positron source NEPOMUC

NASA Astrophysics Data System (ADS)

Piochacz, Christian; Kögel, Gottfried; Egger, Werner; Hugenschmidt, Christoph; Mayer, Jakob; Schreckenbach, Klaus; Sperr, Peter; Stadlbauer, Martin; Dollinger, Günther

2008-10-01

A remoderator for the high intensity positron source NEPOMUC was developed and installed at the beam facility. A beam of remoderated positrons could be produced with different energies and a diameter of less than 2 mm was obtained. The efficiency of the remoderation setup was determined to be 5%. Due to the brilliance of the remoderated beam, the measurements at the coincidence Doppler broadening spectrometer (CDBS) and at the positron annihilation induced Auger electron spectrometer (PAES) could be improved. The setup and functionality of the remoderation device is presented as well as the first measurements at the remoderator, CDBS and PAES.

Particle physics. Positrons ride the wave

DOE PAGES

Piot, Philippe

2015-08-26

Here, experiments reveal that positrons — the antimatter equivalents of electrons — can be rapidly accelerated using a plasma wave. The findings pave the way to high-energy electron–positron particle colliders.

Analysis of Advanced Modular Power Systems (AMPS) for Deep Space Exploration

NASA Technical Reports Server (NTRS)

Oeftering, Richard; Soeder, James F.; Beach, Ray

2014-01-01

The Advanced Modular Power Systems (AMPS) project is developing a modular approach to spacecraft power systems for exploration beyond Earth orbit. AMPS is intended to meet the need of reducing the cost of design development, test and integration and also reducing the operational logistics cost of supporting exploration missions. AMPS seeks to establish modular power building blocks with standardized electrical, mechanical, thermal and data interfaces that can be applied across multiple exploration vehicles. The presentation discusses the results of a cost analysis that compares the cost of the modular approach against a traditional non-modular approach.

In Silico Investigation of a Surgical Interface for Remote Control of Modular Miniature Robots in Minimally Invasive Surgery

PubMed Central

Zygomalas, Apollon; Giokas, Konstantinos; Koutsouris, Dimitrios

2014-01-01

Aim. Modular mini-robots can be used in novel minimally invasive surgery techniques like natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single site (LESS) surgery. The control of these miniature assistants is complicated. The aim of this study is the in silico investigation of a remote controlling interface for modular miniature robots which can be used in minimally invasive surgery. Methods. The conceptual controlling system was developed, programmed, and simulated using professional robotics simulation software. Three different modes of control were programmed. The remote controlling surgical interface was virtually designed as a high scale representation of the respective modular mini-robot, therefore a modular controlling system itself. Results. With the proposed modular controlling system the user could easily identify the conformation of the modular mini-robot and adequately modify it as needed. The arrangement of each module was always known. The in silico investigation gave useful information regarding the controlling mode, the adequate speed of rearrangements, and the number of modules needed for efficient working tasks. Conclusions. The proposed conceptual model may promote the research and development of more sophisticated modular controlling systems. Modular surgical interfaces may improve the handling and the dexterity of modular miniature robots during minimally invasive procedures. PMID:25295187

In silico investigation of a surgical interface for remote control of modular miniature robots in minimally invasive surgery.

PubMed

Zygomalas, Apollon; Giokas, Konstantinos; Koutsouris, Dimitrios

2014-01-01

Aim. Modular mini-robots can be used in novel minimally invasive surgery techniques like natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single site (LESS) surgery. The control of these miniature assistants is complicated. The aim of this study is the in silico investigation of a remote controlling interface for modular miniature robots which can be used in minimally invasive surgery. Methods. The conceptual controlling system was developed, programmed, and simulated using professional robotics simulation software. Three different modes of control were programmed. The remote controlling surgical interface was virtually designed as a high scale representation of the respective modular mini-robot, therefore a modular controlling system itself. Results. With the proposed modular controlling system the user could easily identify the conformation of the modular mini-robot and adequately modify it as needed. The arrangement of each module was always known. The in silico investigation gave useful information regarding the controlling mode, the adequate speed of rearrangements, and the number of modules needed for efficient working tasks. Conclusions. The proposed conceptual model may promote the research and development of more sophisticated modular controlling systems. Modular surgical interfaces may improve the handling and the dexterity of modular miniature robots during minimally invasive procedures.

Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus‐like particle

PubMed Central

Tekewe, Alemu; Connors, Natalie K.; Middelberg, Anton P. J.

2016-01-01

Abstract Virus‐like particles (VLPs) and capsomere subunits have shown promising potential as safe and effective vaccine candidates. They can serve as platforms for the display of foreign epitopes on their surfaces in a modular architecture. Depending on the physicochemical properties of the antigenic modules, modularization may affect the expression, solubility and stability of capsomeres, and VLP assembly. In this study, three module designs of a rotavirus hydrophobic peptide (RV10) were synthesized using synthetic biology. Among the three synthetic modules, modularization of the murine polyomavirus VP1 with a single copy of RV10 flanked by long linkers and charged residues resulted in the expression of stable modular capsomeres. Further employing the approach of module titration of RV10 modules on each capsomere via Escherichia coli co‐expression of unmodified VP1 and modular VP1‐RV10 successfully translated purified modular capomeres into modular VLPs when assembled in vitro. Our results demonstrate that tailoring the physicochemical properties of modules to enhance modular capsomeres stability is achievable through synthetic biology designs. Combined with module titration strategy to avoid steric hindrance to intercapsomere interactions, this allows bioprocessing of bacterially produced in vitro assembled modular VLPs. PMID:27222486

Design strategies to address the effect of hydrophobic epitope on stability and in vitro assembly of modular virus-like particle.

PubMed

Tekewe, Alemu; Connors, Natalie K; Middelberg, Anton P J; Lua, Linda H L

2016-08-01

Virus-like particles (VLPs) and capsomere subunits have shown promising potential as safe and effective vaccine candidates. They can serve as platforms for the display of foreign epitopes on their surfaces in a modular architecture. Depending on the physicochemical properties of the antigenic modules, modularization may affect the expression, solubility and stability of capsomeres, and VLP assembly. In this study, three module designs of a rotavirus hydrophobic peptide (RV10) were synthesized using synthetic biology. Among the three synthetic modules, modularization of the murine polyomavirus VP1 with a single copy of RV10 flanked by long linkers and charged residues resulted in the expression of stable modular capsomeres. Further employing the approach of module titration of RV10 modules on each capsomere via Escherichia coli co-expression of unmodified VP1 and modular VP1-RV10 successfully translated purified modular capomeres into modular VLPs when assembled in vitro. Our results demonstrate that tailoring the physicochemical properties of modules to enhance modular capsomeres stability is achievable through synthetic biology designs. Combined with module titration strategy to avoid steric hindrance to intercapsomere interactions, this allows bioprocessing of bacterially produced in vitro assembled modular VLPs. © 2016 The Protein Society.

Progress toward magnetic confinement of a positron-electron plasma: nearly 100% positron injection efficiency into a dipole trap

NASA Astrophysics Data System (ADS)

Stoneking, Matthew

2017-10-01

The hydrogen atom provides the simplest system and in some cases the most precise one for comparing theory and experiment in atomics physics. The field of plasma physics lacks an experimental counterpart, but there are efforts underway to produce a magnetically confined positron-electron plasma that promises to represent the simplest plasma system. The mass symmetry of positron-electron plasma makes it particularly tractable from a theoretical standpoint and many theory papers have been published predicting modified wave and stability properties in these systems. Our approach is to utilize techniques from the non-neutral plasma community to trap and accumulate electrons and positrons prior to mixing in a magnetic trap with good confinement properties. Ultimately we aim to use a levitated superconducting dipole configuration fueled by positrons from a reactor-based positron source and buffer-gas trap. To date we have conducted experiments to characterize and optimize the positron beam and test strategies for injecting positrons into the field of a supported permanent magnet by use of ExB drifts and tailored static and dynamic potentials applied to boundary electrodes and to the magnet itself. Nearly 100% injection efficiency has been achieved under certain conditions and some fraction of the injected positrons are confined for as long as 400 ms. These results are promising for the next step in the project which is to use an inductively energized high Tc superconducting coil to produce the dipole field, initially in a supported configuration, but ultimately levitated using feedback stabilization. Work performed with the support of the German Research Foundation (DFG), JSPS KAKENHI, NIFS Collaboration Research Program, and the UCSD Foundation.

Defect studies of nanocrystalline zirconia powders and sintered ceramics

NASA Astrophysics Data System (ADS)

Čížek, Jakub; Melikhova, Oksana; Procházka, Ivan; Kuriplach, Jan; Kužel, Radomír; Brauer, Gerhard; Anwand, Wolfgang; Konstantinova, Tatyana E.; Danilenko, Igor A.

2010-01-01

The main objective of the present paper is to communicate a study of defects behavior in zirconia-based nanomaterials—pressure-compacted yttria-stabilized zirconia (YSZ) nanopowders with different contents of Y2O3 and ceramics obtained by sintering the YZS nanopowders. In addition, YZS single crystals were also investigated. Positron annihilation techniques including positron lifetime and coincidence Doppler broadening with a conventional positron source and Doppler broadening experiments on a monoenergetic positron beam were involved in this study as the principal tools. These techniques were supplemented with transmission electron microscopy and x-ray diffraction observations. In order to get better support of the experimental data interpretation, the state-of-art theoretical calculations of positron parameters were performed for the perfect ZrO2 lattice and selected defect configurations in the YSZ. Theoretical calculations have indicated that neither the oxygen vacancies nor their neutral complexes with substitutional yttrium atoms are capable of positron trapping. On the other hand, the zirconium vacancies are deep positron traps and obviously are responsible for the saturated positron trapping observed in the YSZ single crystals. In the compacted YSZ nanopowders, a majority of positrons is trapped either in the vacancylike defects situated in the negative space-charge layers along grain boundaries (τ1≈185ps) or in vacancy clusters at intersections of grain boundaries (τ2≈370ps) . The intensity ratio I2/I1 was found to be correlated with the mean grain size d as I2/I1˜d-2 . A small fraction of positrons (≈10%) form positronium in large pores (τ3≈2ns,τ4≈30ns) . A significant grain growth during sintering of the YSZ nanopowders above 1000°C was observed.

Ultrashort megaelectronvolt positron beam generation based on laser-accelerated electrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Tongjun; Shen, Baifei, E-mail: bfshen@mail.shcnc.ac.cn; Xu, Jiancai, E-mail: jcxu@siom.ac.cn

Experimental generation of ultrashort MeV positron beams with high intensity and high density using a compact laser-driven setup is reported. A high-density gas jet is employed experimentally to generate MeV electrons with high charge; thus, a charge-neutralized MeV positron beam with high density is obtained during laser-accelerated electrons irradiating high-Z solid targets. It is a novel electron–positron source for the study of laboratory astrophysics. Meanwhile, the MeV positron beam is pulsed with an ultrashort duration of tens of femtoseconds and has a high peak intensity of 7.8 × 10{sup 21} s{sup −1}, thus allows specific studies of fast kinetics in millimeter-thick materials withmore » a high time resolution and exhibits potential for applications in positron annihilation spectroscopy.« less

Method for on-line evaluation of materials using prompt gamma ray analysis

DOEpatents

Akers, Douglas W [Idaho Falls, ID

2009-12-08

A method for evaluating a material specimen comprises: Mounting a neutron source and a detector adjacent the material specimen; bombarding the material specimen with neutrons from the neutron source to create prompt gamma rays within the material specimen, some of the prompt gamma rays being emitted from the material specimen, some of the prompt gamma rays resulting in the formation of positrons within the material specimen by pair production; collecting positron annihilation data by detecting with the detector at least one emitted annihilation gamma ray resulting from the annihilation of a positron; storing the positron annihilation data on a data storage system for later retrieval and processing; and continuing to collect and store positron annihilation data, the continued collected and stored positron annihilation data being indicative of an accumulation of lattice damage over time.

Positron-Induced Luminescence.

PubMed

Stenson, E V; Hergenhahn, U; Stoneking, M R; Pedersen, T Sunn

2018-04-06

We report on the observation that low-energy positrons incident on a phosphor screen produce significantly more luminescence than electrons do. For two different wide-band-gap semiconductor phosphors (ZnS:Ag and ZnO:Zn), we compare the luminescent response to a positron beam with the response to an electron beam. For both phosphors, the positron response is significantly brighter than the electron response, by a factor that depends strongly on incident energy (0-5 keV). Positrons with just a few tens of electron-volts of energy (for ZnS:Ag) or less (for ZnO:Zn) produce as much luminescence as is produced by electrons with several kilo-electron-volts. We attribute this effect to valence band holes and excited electrons produced by positron annihilation and subsequent Auger processes. These results demonstrate a valuable approach for addressing long-standing questions about luminescent materials.

Positron-Induced Luminescence

NASA Astrophysics Data System (ADS)

Stenson, E. V.; Hergenhahn, U.; Stoneking, M. R.; Pedersen, T. Sunn

2018-04-01

We report on the observation that low-energy positrons incident on a phosphor screen produce significantly more luminescence than electrons do. For two different wide-band-gap semiconductor phosphors (ZnS:Ag and ZnO:Zn), we compare the luminescent response to a positron beam with the response to an electron beam. For both phosphors, the positron response is significantly brighter than the electron response, by a factor that depends strongly on incident energy (0-5 keV). Positrons with just a few tens of electron-volts of energy (for ZnS:Ag) or less (for ZnO:Zn) produce as much luminescence as is produced by electrons with several kilo-electron-volts. We attribute this effect to valence band holes and excited electrons produced by positron annihilation and subsequent Auger processes. These results demonstrate a valuable approach for addressing long-standing questions about luminescent materials.

Ultra-Intense Short-Pulse Pair Creation Using the Texas Petawatt Laser

NASA Astrophysics Data System (ADS)

Liang, Edison; Henderson, Alexander; Clarke, Taylor; Taylor, Devin; Chaguine, Petr; Serratto, Kristina; Riley, Nathan; Dyer, Gilliss; Donovan, Michael; Ditmire, Todd

2013-10-01

We report results from the 2012 pair creation experiment using the Texas Petawatt Laser. Up to 1011 positrons per steradian were detected using 100 Joule pulses from the Texas Petawatt Laser to irradiate gold targets, with peak laser intensities up to 1.9 × 1021W/cm2 and pulse durations as short as 130 fs. Positron-to-electron ratios exceeding 20% were measured on some shots. The positron energy, positron yield per unit laser energy, and inferred positron density are significantly higher than those reported in previous experiments. This confirms that, for a given laser energy, higher intensity and shorter pulses irradiating thicker targets are more favorable for pair creation. Narrow-band high-energy positrons up to 23 MeV were observed from thin targets. Supported by DOE Grant DE-SC-0001481 and Rice FIF.

Surface states and annihilation characteristics of positrons trapped at the oxidized Cu(100) surface

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Weiss, A. H.

2013-06-01

In this work we present the results of theoretical studies of positron surface and bulk states and annihilation probabilities of surface-trapped positrons with relevant core electrons at the oxidized Cu(100) surface under conditions of high oxygen coverage. Oxidation of the Cu(100) surface has been studied by performing an ab-initio investigation of the stability and electronic structure of the Cu(100) missing row reconstructed surface at various on-surface and subsurface oxygen coverages ranging from 0.5 to 1.5 monolayers using density functional theory (DFT). All studied structures have been found to be energetically more favorable as compared to structures formed by purely on-surface oxygen adsorption. The observed decrease in the positron work function when oxygen atoms occupy on-surface and subsurface sites has been attributed to a significant charge redistribution within the first two layers, buckling effects within each layer and an interlayer expansion. The computed positron binding energy, positron surface state wave function, and annihilation probabilities of the surface trapped positrons with relevant core electrons demonstrate their sensitivity to oxygen coverage, atomic structure of the topmost layers of surfaces, and charge transfer effects. Theoretical results are compared with experimental data obtained from studies of oxidation of the Cu(100) surface using positron annihilation induced Auger electron spectroscopy (PAES). The results presented provide an explanation for the changes observed in the probability of annihilation of surface trapped positrons with Cu 3p core-level electrons as a function of annealing temperature.

Positron probes of the Ge(1 0 0) surface: The effects of surface reconstructions and electron positron correlations on positron trapping and annihilation characteristics

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Jung, E.; Weiss, A. H.

2007-08-01

Positron annihilation induced Auger electron spectroscopy (PAES) has been applied to study the Ge(1 0 0) surface. The high-resolution PAES spectrum from the Ge(1 0 0) surface displays several strong Auger peaks corresponding to M4,5N1N2,3, M2,3M4,5M4,5, M2,3M4,5V and M1M4,5M4,5 Auger transitions. The integrated peak intensities of Auger transitions are used to obtain experimental annihilation probabilities for the Ge 3d and 3p core level electrons. These experimental results are analyzed by performing calculations of positron surface states and annihilation characteristics of surface trapped positrons with relevant Ge core-level electrons for the non-reconstructed and reconstructed Ge(1 0 0)-p(2 × 1), Ge(1 0 0)-p(2 × 2) and Ge(1 0 0)-c(4 × 2) surfaces. It is found that the positron surface state wave function extends into the Ge lattice in the regions where atoms are displaced from their ideal terminated positions due to reconstructions. Estimates of the positron binding energy and the positron annihilation characteristics reveal their sensitivity to the specific atomic structure of the topmost layers of Ge(1 0 0). A comparison with PAES data reveals an agreement with theoretical core annihilation probabilities for the Auger transitions considered.

Satellite Observations of Annihilation of Positrons Produced at the Sun, the Earth, and Center of our Galaxy

NASA Astrophysics Data System (ADS)

Share, G. H.; Murphy, R. J.; Lin, R. P.

2007-05-01

Positrons are created in nuclear interactions that produce β +-unstable nuclei and pi+ mesons. Satellites remotely observe positron production when they annihilate with electrons yielding the characteristic line at 511 keV. Radiation detectors such as the germanium diodes on the Ramaty High-Energy Solar Spectrocopic Imager (RHESSI) observe this line from positrons by nuclei activated in the spacecraft by proton interactions during transit through the Earth's radiation belts and from cosmic radiation. This forms an intense background for solar and astrophysical observations. RHESSI and other satellites have observed positron annihilation in over 50 solar flares. These measurements provide information on the temperature, density, and ionization state of solar atmosphere where the positrons annihilate. The measurements suggest that up to a few kg of positrons are produced in these flares. Detectable annihilation-line radiation is also emitted from the Earth's atmosphere in interactions of cosmic rays and solar energetic particles. An extended annihilation-line source has also been detected within about 10 degrees of the center of the Milky Way that is attributed to positrons released in radioactive decays of nuclei with long half-lives produced in supernovae, novae, and other stellar explosions. From 1980 to 1988 NASA's Solar Maximum Mission satellite also detected belts of positrons emitted by nuclear reactors onboard KOSMOS satellites and trapped temporarily in the Earth's magnetic field. This work was supported by NASA Supporting Research & Technology grants.

Modular workcells: modern methods for laboratory automation.

PubMed

Felder, R A

1998-12-01

Laboratory automation is beginning to become an indispensable survival tool for laboratories facing difficult market competition. However, estimates suggest that only 8% of laboratories will be able to afford total laboratory automation systems. Therefore, automation vendors have developed alternative hardware configurations called 'modular automation', to fit the smaller laboratory. Modular automation consists of consolidated analyzers, integrated analyzers, modular workcells, and pre- and post-analytical automation. These terms will be defined in this paper. Using a modular automation model, the automated core laboratory will become a site where laboratory data is evaluated by trained professionals to provide diagnostic information to practising physicians. Modem software information management and process control tools will complement modular hardware. Proper standardization that will allow vendor-independent modular configurations will assure success of this revolutionary new technology.

The Modular need for the Division Signal Battalion

DTIC Science & Technology

2017-06-09

findings and analyzes them to expand on them. It is with these findings and subsequent analysis that the case studies shape the answer to the three...These case studies focus on the signal leadership development and how it occurred in the pre-modular force structure, during modularity, and the...the comparative case study research. The case studies focus on signal leader development in a pre-modular signal force, a modular signal force, and

Modular Fixturing System

NASA Technical Reports Server (NTRS)

Littell, Justin Anderson (Inventor); Street, Jon P. (Inventor)

2017-01-01

The modular fixturing system of the present invention is modular, reusable and capable of significant customization, both in terms of system radius and system height, allowing it to be arranged and rearranged in numerous unique configurations. The system includes multiple modular stanchions having stanchion shafts and stanchion feet that removably attach to apertures in a table. Angle brackets attached to the modular stanchions support shelves. These shelves in turn provide support to work pieces during fabrication processes such as welding.

Simultaneous dual modality optical and MR imaging of mouse dorsal skin-fold window chamber

NASA Astrophysics Data System (ADS)

Salek, Mir Farrokh; Pagel, Mark D.; Gmitro, Arthur F.

2011-02-01

Optical imaging and MRI have both been used extensively to study tumor microenvironment. The two imaging modalities are complementary and can be used to cross-validate one another for specific measurements. We have developed a modular platform that is capable of doing optical microscopy inside an MRI instrument. To do this, an optical relay system transfers the image to outside of the MR bore to a commercial grade CCD camera. This enables simultaneous optical and MR imaging of the same tissue and thus creates the ideal situation for comparative or complementary studies using both modalities. Initial experiments have been done using GFP labeled prostate cancer cells implanted in mouse dorsal skin fold window chamber. Vascular hemodynamics and vascular permeability were studied using our imaging system. Towards this goal, we developed a dual MR-Optical contrast agent by labeling BSA with both Gd-DTPA and Alexa Fluor. Overall system design and results of these preliminary vascular studies are presented.

Nonlinear Plasma Experiments in Geospace with Gigawatts of RF Power at HAARP

NASA Astrophysics Data System (ADS)

Sheerin, J. P.; Rayyan, N.; Watkins, B. J.; Bristow, W. A.; Bernhardt, P. A.

2014-10-01

The HAARP phased-array HF transmitter at Gakona, AK delivers up to 3.6 GW (ERP) of HF power in the range of 2.8 - 10 MHz to the ionosphere with millisecond pointing, power modulation, and frequency agility. HAARP's unique features have enabled the conduct of a number of nonlinear plasma experiments in the interaction region of overdense ionospheric plasma including stimulated electromagnetic emissions (SEE), artificial aurora, artificial ionization layers, VLF wave-particle interactions in the magnetosphere, strong Langmuir turbulence (SLT) and suprathermal electron acceleration. Diagnostics include the Modular UHF Ionospheric Radar (MUIR) sited at HAARP, the SuperDARN-Kodiak HF radar, spacecraft radio beacons, HF receivers to record stimulated electromagnetic emissions (SEE) and telescopes and cameras for optical emissions. We report on short timescale ponderomotive overshoot effects, artificial field-aligned irregularities (AFAI), the aspect angle dependence of the intensity of the plasma line, and suprathermal electrons. Applications are made to the study and control of irregularities affecting spacecraft communication and navigation systems.

Webcams for Bird Detection and Monitoring: A Demonstration Study

PubMed Central

Verstraeten, Willem W.; Vermeulen, Bart; Stuckens, Jan; Lhermitte, Stefaan; Van der Zande, Dimitry; Van Ranst, Marc; Coppin, Pol

2010-01-01

Better insights into bird migration can be a tool for assessing the spread of avian borne infections or ecological/climatologic issues reflected in deviating migration patterns. This paper evaluates whether low budget permanent cameras such as webcams can offer a valuable contribution to the reporting of migratory birds. An experimental design was set up to study the detection capability using objects of different size, color and velocity. The results of the experiment revealed the minimum size, maximum velocity and contrast of the objects required for detection by a standard webcam. Furthermore, a modular processing scheme was proposed to track and follow migratory birds in webcam recordings. Techniques such as motion detection by background subtraction, stereo vision and lens distortion were combined to form the foundation of the bird tracking algorithm. Additional research to integrate webcam networks, however, is needed and future research should enforce the potential of the processing scheme by exploring and testing alternatives of each individual module or processing step. PMID:22319308

Ultrahigh-speed X-ray imaging of hypervelocity projectiles

NASA Astrophysics Data System (ADS)

Miller, Stuart; Singh, Bipin; Cool, Steven; Entine, Gerald; Campbell, Larry; Bishel, Ron; Rushing, Rick; Nagarkar, Vivek V.

2011-08-01

High-speed X-ray imaging is an extremely important modality for healthcare, industrial, military and research applications such as medical computed tomography, non-destructive testing, imaging in-flight projectiles, characterizing exploding ordnance, and analyzing ballistic impacts. We report on the development of a modular, ultrahigh-speed, high-resolution digital X-ray imaging system with large active imaging area and microsecond time resolution, capable of acquiring at a rate of up to 150,000 frames per second. The system is based on a high-resolution, high-efficiency, and fast-decay scintillator screen optically coupled to an ultra-fast image-intensified CCD camera designed for ballistic impact studies and hypervelocity projectile imaging. A specially designed multi-anode, high-fluence X-ray source with 50 ns pulse duration provides a sequence of blur-free images of hypervelocity projectiles traveling at speeds exceeding 8 km/s (18,000 miles/h). This paper will discuss the design, performance, and high frame rate imaging capability of the system.

MOSES: a modular sensor electronics system for space science and commercial applications

NASA Astrophysics Data System (ADS)

Michaelis, Harald; Behnke, Thomas; Tschentscher, Matthias; Mottola, Stefano; Neukum, Gerhard

1999-10-01

The camera group of the DLR--Institute of Space Sensor Technology and Planetary Exploration is developing imaging instruments for scientific and space applications. One example is the ROLIS imaging system of the ESA scientific space mission `Rosetta', which consists of a descent/downlooking and a close-up imager. Both are parts of the Rosetta-Lander payload and will operate in the extreme environment of a cometary nucleus. The Rosetta Lander Imaging System (ROLIS) will introduce a new concept for the sensor electronics, which is referred to as MOSES (Modula Sensor Electronics System). MOSES is a 3D miniaturized CCD- sensor-electronics which is based on single modules. Each of the modules has some flexibility and enables a simple adaptation to specific application requirements. MOSES is mainly designed for space applications where high performance and high reliability are required. This concept, however, can also be used in other science or commercial applications. This paper describes the concept of MOSES, its characteristics, performance and applications.

The precision measurement and assembly for miniature parts based on double machine vision systems

NASA Astrophysics Data System (ADS)

Wang, X. D.; Zhang, L. F.; Xin, M. Z.; Qu, Y. Q.; Luo, Y.; Ma, T. M.; Chen, L.

2015-02-01

In the process of miniature parts' assembly, the structural features on the bottom or side of the parts often need to be aligned and positioned. The general assembly equipment integrated with one vertical downward machine vision system cannot satisfy the requirement. A precision automatic assembly equipment was developed with double machine vision systems integrated. In the system, a horizontal vision system is employed to measure the position of the feature structure at the parts' side view, which cannot be seen with the vertical one. The position measured by horizontal camera is converted to the vertical vision system with the calibration information. By careful calibration, the parts' alignment and positioning in the assembly process can be guaranteed. The developed assembly equipment has the characteristics of easy implementation, modularization and high cost performance. The handling of the miniature parts and assembly procedure were briefly introduced. The calibration procedure was given and the assembly error was analyzed for compensation.

Webcams for bird detection and monitoring: a demonstration study.

PubMed

Verstraeten, Willem W; Vermeulen, Bart; Stuckens, Jan; Lhermitte, Stefaan; Van der Zande, Dimitry; Van Ranst, Marc; Coppin, Pol

2010-01-01

Better insights into bird migration can be a tool for assessing the spread of avian borne infections or ecological/climatologic issues reflected in deviating migration patterns. This paper evaluates whether low budget permanent cameras such as webcams can offer a valuable contribution to the reporting of migratory birds. An experimental design was set up to study the detection capability using objects of different size, color and velocity. The results of the experiment revealed the minimum size, maximum velocity and contrast of the objects required for detection by a standard webcam. Furthermore, a modular processing scheme was proposed to track and follow migratory birds in webcam recordings. Techniques such as motion detection by background subtraction, stereo vision and lens distortion were combined to form the foundation of the bird tracking algorithm. Additional research to integrate webcam networks, however, is needed and future research should enforce the potential of the processing scheme by exploring and testing alternatives of each individual module or processing step.

Neural networks for sign language translation

NASA Astrophysics Data System (ADS)

Wilson, Beth J.; Anspach, Gretel

1993-09-01

A neural network is used to extract relevant features of sign language from video images of a person communicating in American Sign Language or Signed English. The key features are hand motion, hand location with respect to the body, and handshape. A modular hybrid design is under way to apply various techniques, including neural networks, in the development of a translation system that will facilitate communication between deaf and hearing people. One of the neural networks described here is used to classify video images of handshapes into their linguistic counterpart in American Sign Language. The video image is preprocessed to yield Fourier descriptors that encode the shape of the hand silhouette. These descriptors are then used as inputs to a neural network that classifies their shapes. The network is trained with various examples from different signers and is tested with new images from new signers. The results have shown that for coarse handshape classes, the network is invariant to the type of camera used to film the various signers and to the segmentation technique.

Positron and electron energy bands in several ionic crystals using restricted Hartree-Fock method

NASA Astrophysics Data System (ADS)

Kunz, A. B.; Waber, J. T.

1981-08-01

Using a restricted Hartree-Fock formalism and suitably localized and symmetrized wave functions, both the positron and electron energy bands were calculated for NaF, MgO and NiO. The lowest positron state at Γ 1 lies above the vacuum level and negative work functions are predicted. Positron annihilation rates were calculated and found to be in good agreement with measured lifetimes.

Studies of oxidation and thermal reduction of the Cu(100) surface using a slow positron beam

NASA Astrophysics Data System (ADS)

Maddox, W. B.; Fazleev, N. G.; Nadesalingam, M. P.; Weiss, A. H.

2007-10-01

Positron probes of surfaces of oxides that play a fundamental role in modern science and technology are capable to non-destructively provide information that is both unique to the probe and complimentary to that extracted using other more standard techniques. We discuss recent progress in studies of oxidation and thermal reduction of the Cu(100) surface using positron-annihilation-induced Auger-electron spectroscopy (PAES). PAES measurements show a large increase in the intensity of the Cu M2,3VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300 C. The intensity then decreases monotonically as the annealing temperature is increased to 600 C. Experimental PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface and surface reconstruction. The effects of oxygen adsorption and defects on localization of the positron surface state wave function and positron annihilation characteristics are also analyzed. Possible explanations are provided for the observed behavior of the intensity of the positron annihilation induced Cu M2,3VV Auger peak with changes of the annealing temperature.

A Modularized Counselor-Education Program.

ERIC Educational Resources Information Center

Miller, Thomas V.; Dimattia, Dominic J.

1978-01-01

Counselor-education programs may be enriched through the use of modularized learning experiences. This article notes several recent articles on competency-based counselor education, the concepts of simulation and modularization, and describes the process of developing a modularized master's program at the University of Bridgeport in Connecticut.…

On the classification of weakly integral modular categories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bruillard, Paul; Galindo, César; Ng, Siu-Hung

In this paper we classify all modular categories of dimension 4m, where m is an odd square-free integer, and all rank 6 and rank 7 weakly integral modular categories. This completes the classification of weakly integral modular categories through rank 7. In particular, our results imply that all integral modular categories of rank at most 7 are pointed (that is, every simple object has dimension 1). All the non-integral (but weakly integral) modular categories of ranks 6 and 7 have dimension 4m, with m an odd square free integer, so their classification is an application of our main result. Themore » classification of rank 7 integral modular categories is facilitated by an analysis of the two group actions on modular categories: the Galois group of the field generated by the entries of the S-matrix and the group of invertible isomorphism classes of objects. We derive some valuable arithmetic consequences from these actions.« less

High sensitivity of positrons to oxygen vacancies and to copper-oxygen chain disorder in YBa2Cu3O(7-x)

NASA Astrophysics Data System (ADS)

von Stetten, E. C.; Berko, S.; Li, X. S.; Lee, R. R.; Brynestad, J.

1988-05-01

Temperature-dependent positron-electron momentum densities have been studied by two-dimensional angular correlation of annihilation radiation from 10 to 320 K in YBa2Cu3O(7-x) samples. The positron ground-state charge density, computed by the linearized augmented-plane-wave method, indicates that in YBa2Cu3O7 delocalized positrons sample preferentially the linear copper-oxygen chains. Positron localization due to disorder in these chains is invoked to explain the striking differences observed between superconducting (x = about 0.02) and nonsuperconducting (x = about 0.70) samples.

Cation vacancies in ferroelectric PbTiO3 and Pb(Zr,Ti)O3 : A positron annihilation lifetime spectroscopy study

NASA Astrophysics Data System (ADS)

Keeble, D. J.; Singh, S.; Mackie, R. A.; Morozov, M.; McGuire, S.; Damjanovic, D.

2007-10-01

Positron annihilation lifetime spectroscopy measurements identify A - and B -site cation vacancies in ferroelectric perovskite oxides (ABO3) . Crystal PbTiO3 and ceramic lead zirconium titanate (PZT) were studied and gave consistent values for the lifetime resulting from positron localization at lead vacancies VPb . Positron trapping to B -site vacancies was inferred in PZT. Temperature dependent studies showed that the defect specific trapping rate was higher for VB compared to VPb , consistent with the larger negative charge. Doping PZT with Fe increased the fraction positron trapping to VB compared to VPb -type defects.

Simulation and Modeling of Positrons and Electrons in advanced Time-of-Flight Positron Annihilation Induced Auger Electron Spectroscopy Systems

NASA Astrophysics Data System (ADS)

Joglekar, Prasad; Shastry, Karthik; Satyal, Suman; Weiss, Alexander

2011-10-01

Time of Flight Positron Annihilation Induced Auger Electron Spectroscopy (T-O-F PAES) is a highly surface selective analytical technique in which elemental identification is accomplished through a measurement of the flight time distributions of Auger electrons resulting from the annihilation of core electron by positrons. SIMION charged particle optics simulation software was used to model the trajectories both the incident positrons and outgoing electrons in our existing T-O-F PAES system as well as in a new system currently under construction in our laboratory. The implication of these simulation regarding the instrument design and performance are discussed.

Measurement of positron annihilation lifetimes for positron burst by multi-detector array

NASA Astrophysics Data System (ADS)

Wang, B. Y.; Kuang, P.; Liu, F. Y.; Han, Z. J.; Cao, X. Z.; Zhang, P.

2018-03-01

It is currently impossible to exploit the timing information in a gamma-ray pulse generated within nanoseconds when a high-intensity positron burst annihilation event occurs in a target using conventional single-detector methods. A state-of-the-art solution to the problem is proposed in this paper. In this approach, a multi-detector array composed of many independent detection cells mounted spherically around the target is designed to detect the time distribution of the annihilated gamma rays generated following, in particular, a positron burst emitting huge amounts of positrons in a short pulse duration, even less than a few nano- or picoseconds.

Dynamic behavior of ion acoustic waves in electron-positron-ion magnetoplasmas with superthermal electrons and positrons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saha, Asit, E-mail: asit-saha123@rediffmail.com, E-mail: prasantachatterjee1@rediffmail.com; Department of Mathematics, Siksha Bhavana, Visva Bharati University, Santiniketan-731235; Pal, Nikhil

The dynamic behavior of ion acoustic waves in electron-positron-ion magnetoplasmas with superthermal electrons and positrons has been investigated in the framework of perturbed and non-perturbed Kadomtsev-Petviashili (KP) equations. Applying the reductive perturbation technique, we have derived the KP equation in electron-positron-ion magnetoplasma with kappa distributed electrons and positrons. Bifurcations of ion acoustic traveling waves of the KP equation are presented. Using the bifurcation theory of planar dynamical systems, the existence of the solitary wave solutions and the periodic traveling wave solutions has been established. Two exact solutions of these waves have been derived depending on the system parameters. Then, usingmore » the Hirota's direct method, we have obtained two-soliton and three-soliton solutions of the KP equation. The effect of the spectral index κ on propagations of the two-soliton and the three-soliton has been shown. Considering an external periodic perturbation, we have presented the quasi periodic behavior of ion acoustic waves in electron-positron-ion magnetoplasmas.« less

CIRCULAR POLARIZATION OF PULSAR WIND NEBULAE AND THE COSMIC-RAY POSITRON EXCESS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Linden, Tim, E-mail: trlinden@uchicago.edu

2015-02-01

Recent observations by the PAMELA and AMS-02 telescopes have uncovered an anomalous rise in the positron fraction at energies above 10 GeV. One possible explanation for this excess is the production of primary electron/positron pairs through electromagnetic cascades in pulsar magnetospheres. This process results in a high multiplicity of electron/positron pairs within the wind-termination shock of pulsar wind nebulae (PWNe). A consequence of this scenario is that no circular polarization should be observed within PWNe, since the contributions from electrons and positrons exactly cancel. Here we note that current radio instruments are capable of setting meaningful limits on the circular polarizationmore » of synchrotron radiation in PWNe, which observationally test the model for pulsar production of the local positron excess. The observation of a PWN with detectable circular polarization would cast strong doubt on pulsar interpretations of the positron excess, while observations setting strong limits on the circular polarization of PWNe would lend credence to these models. Finally, we indicate which PWNe are likely to provide the best targets for observational tests of the AMS-02 excess.« less

New parameter-free polarization potentials in low-energy positron collisions

NASA Technical Reports Server (NTRS)

Jain, Ashok

1990-01-01

The polarization potential plays a decisive role in shaping up the cross sections in low energy positron collisions with atoms and molecules. However, its inclusion without involving any adjustable parameter, is still a challenge. Various other techniques employed so far for positron collisions are summarized, and a new, nonadjustable and very simple form of the polarization potential for positron-atom (molecule) collisions below the threshold of positronium formation is discussed. This new recently proposed potential is based on the correlation energy of a single positron in a homogeneous electron gas. The correlation energy was calculated by solving the Schrodinger equation of the positron-electron system and fitted to an analytical form in various ranges of the density parameter. In the outside region, the correlation energy is joined smoothly with the correct asymptotic form. This new positron correlation polarization (PCOP) potential was tested on several atomic and molecular targets such as the Ar, CO, and CH4. The results on the total and differential cross sections on these targets are shown along with the experimental data where available.

Low energy positrons as probes of reconstructed semiconductor surfaces.

NASA Astrophysics Data System (ADS)

Fazleev, Nail G.; Weiss, Alex H.

2007-03-01

Positron probes of semiconductor surfaces that play a fundamental role in modern science and technology are capable to non-destructively provide information that is both unique to the probe and complimentary to that extracted using other more standard techniques. We discuss recent progress in studies of the reconstructed Si(100), Si(111), Ge(100), and Ge(111) surfaces, clean and exposed to hydrogen and oxygen, using a surface characterization technique, Positron-Annihilation-Induced Auger-Electron Spectroscopy (PAES). Experimental PAES results are analyzed by performing first-principles calculations of positron surface states and annihilation probabilities of surface-trapped positrons with relevant core electrons for the reconstructed surfaces, taking into account discrete lattice effects, the electronic reorganization due to bonding, and charge redistribution effects at the surface. Effects of the hydrogen and oxygen adsorption on semiconductor surfaces on localization of positron surface state wave functions and annihilation characteristics are also analyzed. Theoretical calculations confirm that PAES intensities, which are proportional to annihilation probabilities of the surface trapped positrons that results in a core hole, are sensitive to the crystal face, surface structure and elemental content of the semiconductors.

Experimental determination of positron-related surface characteristics of 6H-SiC

NASA Astrophysics Data System (ADS)

Nangia, A.; Kim, J. H.; Weiss, A. H.; Brauer, G.

2002-03-01

The positron work function of 6H-SiC was determined to be -2.1±0.1 eV from an analysis of the energy spectrum of positrons reemitted from the surface. The positron reemission yield, highest in the sample inserted into vacuum after atmospheric exposure and cleaning with ethanol, was significantly reduced after sputtering with 3 keV, 125 μA min Ne+ ions. The yield was not recovered even after annealing at 900 °C, presumably due to the stability of sputter induced defects. Sputtering at lower energies caused a smaller decrease in the reemission yield that was largely recovered after annealing at 850 °C. Analysis using electron induced Auger electron spectroscopy and positron-annihilation-induced Auger electron spectroscopy indicated that the surface was Si enriched after sputtering and C enriched after subsequent annealing. Values of positron diffusion length and mobility in the unsputtered material were extracted from the dependence of the reemission yield on the beam energy. The application of SiC as a field-assisted positron moderator is discussed.

The scaling of electron and positron generation in intense laser-solid interactions

DOE PAGES

Chen, Hui; Link, A.; Sentoku, Y.; ...

2015-05-27

This study presents experimental scalings of the electrons and positrons produced by intense laser-target interactions at relativistic laser intensities (10 18–10 20 W cm -2). The data were acquired from three short-pulse laser facilities with laser energies ranging from 80 to 1500 J. We found a non-linear (≈E L 2) scaling of positron yield [Chen et al., Phys. Rev. Lett. 114, 215001 (2015)] and a linear scaling of electron yield with the laser energy. These scalings are explained by theoretical and numerical analyses. Positron acceleration by the target sheath field is confirmed by the positron energy spectrum, which has amore » pronounced peak at energies near the sheath potential, as determined by the observed maximum energies of accelerated protons. The parameters of laser-produced electron-positron jets are summarized together with the theoretical energy scaling. Finally, the measured energy-squared scaling of relativistic electron-positron jets indicates the possibility to create an astrophysically relevant experimental platform with such jets using multi-kilojoule high intensity lasers currently under construction.« less

The scaling of electron and positron generation in intense laser-solid interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Hui; Link, A.; Fiuza, F.

2015-05-15

This paper presents experimental scalings of the electrons and positrons produced by intense laser-target interactions at relativistic laser intensities (10{sup 18}–10{sup 20} W cm{sup −2}). The data were acquired from three short-pulse laser facilities with laser energies ranging from 80 to 1500 J. We found a non-linear (≈E{sub L}{sup 2}) scaling of positron yield [Chen et al., Phys. Rev. Lett. 114, 215001 (2015)] and a linear scaling of electron yield with the laser energy. These scalings are explained by theoretical and numerical analyses. Positron acceleration by the target sheath field is confirmed by the positron energy spectrum, which has a pronouncedmore » peak at energies near the sheath potential, as determined by the observed maximum energies of accelerated protons. The parameters of laser-produced electron-positron jets are summarized together with the theoretical energy scaling. The measured energy-squared scaling of relativistic electron-positron jets indicates the possibility to create an astrophysically relevant experimental platform with such jets using multi-kilojoule high intensity lasers currently under construction.« less

Modular interdependency in complex dynamical systems.

PubMed

Watson, Richard A; Pollack, Jordan B

2005-01-01

Herbert A. Simon's characterization of modularity in dynamical systems describes subsystems as having dynamics that are approximately independent of those of other subsystems (in the short term). This fits with the general intuition that modules must, by definition, be approximately independent. In the evolution of complex systems, such modularity may enable subsystems to be modified and adapted independently of other subsystems, whereas in a nonmodular system, modifications to one part of the system may result in deleterious side effects elsewhere in the system. But this notion of modularity and its effect on evolvability is not well quantified and is rather simplistic. In particular, modularity need not imply that intermodule dependences are weak or unimportant. In dynamical systems this is acknowledged by Simon's suggestion that, in the long term, the dynamical behaviors of subsystems do interact with one another, albeit in an "aggregate" manner--but this kind of intermodule interaction is omitted in models of modularity for evolvability. In this brief discussion we seek to unify notions of modularity in dynamical systems with notions of how modularity affects evolvability. This leads to a quantifiable measure of modularity and a different understanding of its effect on evolvability.

Advantages of semiconductor CZT for medical imaging

NASA Astrophysics Data System (ADS)

Wagenaar, Douglas J.; Parnham, Kevin; Sundal, Bjorn; Maehlum, Gunnar; Chowdhury, Samir; Meier, Dirk; Vandehei, Thor; Szawlowski, Marek; Patt, Bradley E.

2007-09-01

Cadmium zinc telluride (CdZnTe, or CZT) is a room-temperature semiconductor radiation detector that has been developed in recent years for a variety of applications. CZT has been investigated for many potential uses in medical imaging, especially in the field of single photon emission computed tomography (SPECT). CZT can also be used in positron emission tomography (PET) as well as photon-counting and integration-mode x-ray radiography and computed tomography (CT). The principal advantages of CZT are 1) direct conversion of x-ray or gamma-ray energy into electron-hole pairs; 2) energy resolution; 3) high spatial resolution and hence high space-bandwidth product; 4) room temperature operation, stable performance, high density, and small volume; 5) depth-of-interaction (DOI) available through signal processing. These advantages will be described in detail with examples from our own CZT systems. The ability to operate at room temperature, combined with DOI and very small pixels, make the use of multiple, stationary CZT "mini-gamma cameras" a realistic alternative to today's large Anger-type cameras that require motion to obtain tomographic sampling. The compatibility of CZT with Magnetic Resonance Imaging (MRI)-fields is demonstrated for a new type of multi-modality medical imaging, namely SPECT/MRI. For pre-clinical (i.e., laboratory animal) imaging, the advantages of CZT lie in spatial and energy resolution, small volume, automated quality control, and the potential for DOI for parallax removal in pinhole imaging. For clinical imaging, the imaging of radiographically dense breasts with CZT enables scatter rejection and hence improved contrast. Examples of clinical breast images with a dual-head CZT system are shown.

Action of Penetrating Radiation on Radio Parts,

DTIC Science & Technology

1984-05-24

the formation of the pair of particles the electron - positron . This process is called the effect of the formation of electron- positron pairs. Pair...formation can occur during the absorption 7-quantum with the energy, greater than total rest energy of electron and positron (more than the doubled...rest energy of electron, equal to 2mc 2=!.02 MeV). Positron (unstable elementary DOC - 83167601 PAGE 9 particle) in turn interacts with the electron of

Positron production using a 1.7 MV pelletron accelerator

NASA Astrophysics Data System (ADS)

Alcantara, K. F.; Crivelli, P.; Santos, A. C. F.

2013-04-01

We report the foremost phase of a fourth generation positron source, being constructed at the Federal University of Rio de Janeiro. Positron yields are reported by making use of the 19F(p,αe+e-)16O reaction, where the fluorine target is in the form of a CaF2 pellet. Positron production has been observed by detecting 511 keV annihilation gamma rays emerging from the irradiated CaF2 target.

Positron Annihilation Ratio Spectroscopy Study of Electric Fields Applied to Positronium at Material Interfaces

DTIC Science & Technology

2011-03-01

from 142 ns to a few ns [3:3]. Through the application of positron annihilation lifetime spectroscopy (PALS) on a material, the o-Ps lifetime can be...Force Base, Ohio APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. POSITRON ANNIHILATION RATIO SPECTROSCOPY STUDY OF ELECTRIC FIELDS APPLIED TO...protection in the United States. AFIT/GNE/ENP/11-M19 POSITRON ANNIHILATION RATIO SPECTROSCOPY STUDY OF ELECTRIC FIELDS APPLIED TO POSITRONIUM AT

Individual differences and time-varying features of modular brain architecture.

PubMed

Liao, Xuhong; Cao, Miao; Xia, Mingrui; He, Yong

2017-05-15

Recent studies have suggested that human brain functional networks are topologically organized into functionally specialized but inter-connected modules to facilitate efficient information processing and highly flexible cognitive function. However, these studies have mainly focused on group-level network modularity analyses using "static" functional connectivity approaches. How these extraordinary modular brain structures vary across individuals and spontaneously reconfigure over time remain largely unknown. Here, we employed multiband resting-state functional MRI data (N=105) from the Human Connectome Project and a graph-based modularity analysis to systematically investigate individual variability and dynamic properties in modular brain networks. We showed that the modular structures of brain networks dramatically vary across individuals, with higher modular variability primarily in the association cortex (e.g., fronto-parietal and attention systems) and lower variability in the primary systems. Moreover, brain regions spontaneously changed their module affiliations on a temporal scale of seconds, which cannot be simply attributable to head motion and sampling error. Interestingly, the spatial pattern of intra-subject dynamic modular variability largely overlapped with that of inter-subject modular variability, both of which were highly reproducible across repeated scanning sessions. Finally, the regions with remarkable individual/temporal modular variability were closely associated with network connectors and the number of cognitive components, suggesting a potential contribution to information integration and flexible cognitive function. Collectively, our findings highlight individual modular variability and the notable dynamic characteristics in large-scale brain networks, which enhance our understanding of the neural substrates underlying individual differences in a variety of cognition and behaviors. Copyright © 2017 Elsevier Inc. All rights reserved.

Split gradient coils for simultaneous PET-MRI

PubMed Central

Poole, Michael; Bowtell, Richard; Green, Dan; Pittard, Simon; Lucas, Alun; Hawkes, Rob; Carpenter, Adrian

2015-01-01

Combining positron emission tomography (PET) and MRI necessarily involves an engineering tradeoff as the equipment needed for the two modalities vies for the space closest to the region where the signals originate. In one recently described scanner configuration for simultaneous positron emission tomography–MRI, the positron emission tomography detection scintillating crystals reside in an 80-mm gap between the 2 halves of a 1-T split-magnet cryostat. A novel set of gradient and shim coils has been specially designed for this split MRI scanner to include an 110-mm gap from which wires are excluded so as not to interfere with positron detection. An inverse boundary element method was necessarily employed to design the three orthogonal, shielded gradient coils and shielded Z0 shim coil. The coils have been constructed and tested in the hybrid positron emission tomography-MRI system and successfully used in simultaneous positron emission tomography-MRI experiments. PMID:19780167

Probing the positron moderation process using high-intensity, highly polarized slow-positron beams

NASA Technical Reports Server (NTRS)

Van House, J.; Zitzewitz, P. W.

1984-01-01

A highly polarized (P = 0.48 + or - 0.02) intense (500,000/sec) beam of 'slow' (Delta E = about 2 eV) positrons (e+) is generated, and it is shown that it is possible to achieve polarization as high as P = 0.69 + or - 0.04 with reduced intensity. The measured polarization of the slow e+ emitted by five different positron moderators showed no dependence on the moderator atomic number (Z). It is concluded that only source positrons with final kinetic energy below 17 keV contribute to the slow-e+ beam, in disagreement with recent yield functions derived from low-energy measurements. Measurements of polarization and yield with absorbers of different Z between the source and moderator show the effects of the energy and angular distributions of the source positrons on P. The depolarization of fast e+ transmitted through high-Z absorbers has been measured. Applications of polarized slow-e+ beams are discussed.

Four-dimensional positron age-momentum correlation

NASA Astrophysics Data System (ADS)

Ackermann, Ulrich; Löwe, Benjamin; Dickmann, Marcel; Mitteneder, Johannes; Sperr, Peter; Egger, Werner; Reiner, Markus; Dollinger, Günther

2016-11-01

We have performed first four-dimensional age-momentum correlation (4D-AMOC) measurements at a pulsed high intensity positron micro beam and determined the absolute value of the three-dimensional momentum of the electrons annihilating with the positrons in coincidence with the positron age in the sample material. We operated two position sensitive detectors in coincidence to measure the annihilation radiation: a pixelated HPGe-detector and a microchannel plate image intensifier with a CeBr3 scintillator pixel array. The transversal momentum resolution of the 4D-AMOC setup was measured to be about 17 × 10-3 {m}0c (FWHM) and was circa 3.5 times larger than the longitudinal momentum resolution. The total time resolution was 540 ps (FWHM). We measured two samples: a gold foil and a carbon tape at a positron implantation energy of 2 keV. For each sample discrete electron momentum states and their respective positron lifetimes were extracted.

Identification of vacancy defect complexes in transparent semiconducting oxides ZnO, In2O3 and SnO2.

PubMed

Makkonen, Ilja; Korhonen, Esa; Prozheeva, Vera; Tuomisto, Filip

2016-06-08

Positron annihilation spectroscopy, when combined with supporting high-quality modeling of positron states and annihilation in matter, is a powerful tool for detailed defect identification of vacancy-type defects in semiconductors and oxides. Here we demonstrate that the Doppler broadening of the positron annihilation radiation is a very sensitive means for observing the oxygen environment around cation vacancies, the main open-volume defects trapping positrons in measurements made for transparent semiconducting oxides. Changes in the positron annihilation signal due to external manipulation such as irradiation and annealing can be correlated with the associated changes in the sizes of the detected vacancy clusters. Our examples for ZnO, In2O3 and SnO2 demonstrate that oxygen vacancies in oxides can be detected directly using positron annihilation spectroscopy when they are complexed with cation vacancies.

Identification of vacancy defect complexes in transparent semiconducting oxides ZnO, In2O3 and SnO2

NASA Astrophysics Data System (ADS)

Makkonen, Ilja; Korhonen, Esa; Prozheeva, Vera; Tuomisto, Filip

2016-06-01

Positron annihilation spectroscopy, when combined with supporting high-quality modeling of positron states and annihilation in matter, is a powerful tool for detailed defect identification of vacancy-type defects in semiconductors and oxides. Here we demonstrate that the Doppler broadening of the positron annihilation radiation is a very sensitive means for observing the oxygen environment around cation vacancies, the main open-volume defects trapping positrons in measurements made for transparent semiconducting oxides. Changes in the positron annihilation signal due to external manipulation such as irradiation and annealing can be correlated with the associated changes in the sizes of the detected vacancy clusters. Our examples for ZnO, In2O3 and SnO2 demonstrate that oxygen vacancies in oxides can be detected directly using positron annihilation spectroscopy when they are complexed with cation vacancies.

Diffuse Galactic antimatter from faint thermonuclear supernovae in old stellar populations

NASA Astrophysics Data System (ADS)

Crocker, Roland M.; Ruiter, Ashley J.; Seitenzahl, Ivo R.; Panther, Fiona H.; Sim, Stuart; Baumgardt, Holger; Möller, Anais; Nataf, David M.; Ferrario, Lilia; Eldridge, J. J.; White, Martin; Tucker, Brad E.; Aharonian, Felix

2017-06-01

Our Galaxy hosts the annihilation of a few 1043 low-energy positrons every second. Radioactive isotopes capable of supplying such positrons are synthesized in stars, stellar remnants and supernovae. For decades, however, there has been no positive identification of a main stellar positron source, leading to suggestions that many positrons originate from exotic sources like the Galaxy's central supermassive black hole or dark matter annihilation. Here we show that a single type of transient source, deriving from stellar populations of age 3-6 Gyr and yielding ∼0.03 M ⊙ of the positron emitter 44Ti, can simultaneously explain the strength and morphology of the Galactic positron annihilation signal and the Solar System abundance of the 44Ti decay product 44Ca. This transient is likely the merger of two low-mass white dwarfs, observed in external galaxies as the sub-luminous, thermonuclear supernova known as SN 1991bg-like.

Apparatus for the analysis of surfaces in gas environments using Positron Spectroscopy

NASA Astrophysics Data System (ADS)

Satyal, Suman; Lim, Lawrence; Joglekar, Vibek; Kalaskar, Sushant; Shastry, Karthik; Weiss, Alex

2010-10-01

Positron spectroscopy performed with low energy beams can provide highly surface specific information due to the trapping of positrons in an image potential surface state at the time of annihilation. Here we describe a spectrometer that will employ differential pumping to enable us to transport the positrons most of the way from the source to the sample under high vacuum and then to traverse a thin gas layer surrounding the sample. The positrons will be implanted into the sample at energies less than ˜10 keV ensuring that a large fraction will diffuse back to the surface before annihilation. The Elemental content of the surface interacting with the gas environment will then be determined from the Doppler broadened gamma spectra. This system will include a time of flight positron annihilation induced Auger spectrometer (TOF-PAES) which correlates with the Doppler measurements at lower pressures.

Electron and positron fluxes in primary cosmic rays measured with the alpha magnetic spectrometer on the international space station.

PubMed

Aguilar, M; Aisa, D; Alvino, A; Ambrosi, G; Andeen, K; Arruda, L; Attig, N; Azzarello, P; Bachlechner, A; Barao, F; Barrau, A; Barrin, L; Bartoloni, A; Basara, L; Battarbee, M; Battiston, R; Bazo, J; Becker, U; Behlmann, M; Beischer, B; Berdugo, J; Bertucci, B; Bigongiari, G; Bindi, V; Bizzaglia, S; Bizzarri, M; Boella, G; de Boer, W; Bollweg, K; Bonnivard, V; Borgia, B; Borsini, S; Boschini, M J; Bourquin, M; Burger, J; Cadoux, F; Cai, X D; Capell, M; Caroff, S; Casaus, J; Cascioli, V; Castellini, G; Cernuda, I; Cervelli, F; Chae, M J; Chang, Y H; Chen, A I; Chen, H; Cheng, G M; Chen, H S; Cheng, L; Chikanian, A; Chou, H Y; Choumilov, E; Choutko, V; Chung, C H; Clark, C; Clavero, R; Coignet, G; Consolandi, C; Contin, A; Corti, C; Coste, B; Cui, Z; Dai, M; Delgado, C; Della Torre, S; Demirköz, M B; Derome, L; Di Falco, S; Di Masso, L; Dimiccoli, F; Díaz, C; von Doetinchem, P; Du, W J; Duranti, M; D'Urso, D; Eline, A; Eppling, F J; Eronen, T; Fan, Y Y; Farnesini, L; Feng, J; Fiandrini, E; Fiasson, A; Finch, E; Fisher, P; Galaktionov, Y; Gallucci, G; García, B; García-López, R; Gast, H; Gebauer, I; Gervasi, M; Ghelfi, A; Gillard, W; Giovacchini, F; Goglov, P; Gong, J; Goy, C; Grabski, V; Grandi, D; Graziani, M; Guandalini, C; Guerri, I; Guo, K H; Habiby, M; Haino, S; Han, K C; He, Z H; Heil, M; Hoffman, J; Hsieh, T H; Huang, Z C; Huh, C; Incagli, M; Ionica, M; Jang, W Y; Jinchi, H; Kanishev, K; Kim, G N; Kim, K S; Kirn, Th; Kossakowski, R; Kounina, O; Kounine, A; Koutsenko, V; Krafczyk, M S; Kunz, S; La Vacca, G; Laudi, E; Laurenti, G; Lazzizzera, I; Lebedev, A; Lee, H T; Lee, S C; Leluc, C; Li, H L; Li, J Q; Li, Q; Li, Q; Li, T X; Li, W; Li, Y; Li, Z H; Li, Z Y; Lim, S; Lin, C H; Lipari, P; Lippert, T; Liu, D; Liu, H; Lomtadze, T; Lu, M J; Lu, Y S; Luebelsmeyer, K; Luo, F; Luo, J Z; Lv, S S; Majka, R; Malinin, A; Mañá, C; Marín, J; Martin, T; Martínez, G; Masi, N; Maurin, D; Menchaca-Rocha, A; Meng, Q; Mo, D C; Morescalchi, L; Mott, P; Müller, M; Ni, J Q; Nikonov, N; Nozzoli, F; Nunes, P; Obermeier, A; Oliva, A; Orcinha, M; Palmonari, F; Palomares, C; Paniccia, M; Papi, A; Pedreschi, E; Pensotti, S; Pereira, R; Pilo, F; Piluso, A; Pizzolotto, C; Plyaskin, V; Pohl, M; Poireau, V; Postaci, E; Putze, A; Quadrani, L; Qi, X M; Rancoita, P G; Rapin, D; Ricol, J S; Rodríguez, I; Rosier-Lees, S; Rozhkov, A; Rozza, D; Sagdeev, R; Sandweiss, J; Saouter, P; Sbarra, C; Schael, S; Schmidt, S M; Schuckardt, D; Schulz von Dratzig, A; Schwering, G; Scolieri, G; Seo, E S; Shan, B S; Shan, Y H; Shi, J Y; Shi, X Y; Shi, Y M; Siedenburg, T; Son, D; Spada, F; Spinella, F; Sun, W; Sun, W H; Tacconi, M; Tang, C P; Tang, X W; Tang, Z C; Tao, L; Tescaro, D; Ting, Samuel C C; Ting, S M; Tomassetti, N; Torsti, J; Türkoğlu, C; Urban, T; Vagelli, V; Valente, E; Vannini, C; Valtonen, E; Vaurynovich, S; Vecchi, M; Velasco, M; Vialle, J P; Wang, L Q; Wang, Q L; Wang, R S; Wang, X; Wang, Z X; Weng, Z L; Whitman, K; Wienkenhöver, J; Wu, H; Xia, X; Xie, M; Xie, S; Xiong, R Q; Xin, G M; Xu, N S; Xu, W; Yan, Q; Yang, J; Yang, M; Ye, Q H; Yi, H; Yu, Y J; Yu, Z Q; Zeissler, S; Zhang, J H; Zhang, M T; Zhang, X B; Zhang, Z; Zheng, Z M; Zhuang, H L; Zhukov, V; Zichichi, A; Zimmermann, N; Zuccon, P; Zurbach, C

2014-09-19

Precision measurements by the Alpha Magnetic Spectrometer on the International Space Station of the primary cosmic-ray electron flux in the range 0.5 to 700 GeV and the positron flux in the range 0.5 to 500 GeV are presented. The electron flux and the positron flux each require a description beyond a single power-law spectrum. Both the electron flux and the positron flux change their behavior at ∼30  GeV but the fluxes are significantly different in their magnitude and energy dependence. Between 20 and 200 GeV the positron spectral index is significantly harder than the electron spectral index. The determination of the differing behavior of the spectral indices versus energy is a new observation and provides important information on the origins of cosmic-ray electrons and positrons.

Electron and positron interaction with pyrimidine: A theoretical investigation

NASA Astrophysics Data System (ADS)

Sinha, Nidhi; Antony, Bobby

2018-03-01

Pyrimidine (C4H4N2) is considered as the building block of nucleobases, viz., cytosine, thymine and uracil. They provide a blueprint for probing the scattering of radiation by DNA and RNA bases. In this article, we report the elastic and total scattering cross-sections for electron and positron scattering from the pyrimidine molecule, employing a spherical complex optical potential (SCOP) formalism for an extensive energy range of 10 eV to 5 keV. In the case of positron scattering, the original SCOP formalism is modified to adequately solve the positron-target dynamics. Moreover, a reasonable agreement is observed between the present results and other available datasets, for both electron and positron scattering. The cross-sections for electron and positron impact scattering by pyrimidine are necessary input data for codes that seek to simulate radiation damage, and hence are useful to model biomolecular systems.

Electron acoustic solitons in magneto-rotating electron-positron-ion plasma with nonthermal electrons and positrons

NASA Astrophysics Data System (ADS)

Jilani, K.; Mirza, Arshad M.; Iqbal, J.

2015-02-01

The propagation of electron acoustic solitary waves (EASWs) in a magneto-rotating electron-positron-ion (epi) plasma containing cold dynamical electrons, nonthermal electrons and positrons obeying Cairns' distribution have been explored in the stationary background of massive positive ions. Through the linear dispersion relation (LDR) the effects of nonthermal components, magnetic field and rotation have been analyzed, wherein, various limiting cases have been deduced from the LDR. For nonlinear analysis, Korteweg-de Vries (KdV) equation is obtained using the reductive perturbation technique. It is found that in the presence of nonthermal positrons both hump and dip type solitons appear to excite, the structural properties of these solitary waves change drastically with magneto-rotating effects. The present work may be employed to explore and to understand the formation of electron acoustic solitary structures in the space and laboratory plasmas with nonthermal electrons and positrons under magneto-rotating effects.

A novel source of MeV positron bunches driven by energetic protons for PAS application

NASA Astrophysics Data System (ADS)

Tan, Zongquan; Xu, Wenzhen; Liu, Yanfen; Xiao, Ran; Kong, Wei; Ye, Bangjiao

2014-11-01

This paper proposes a novel methodology of MeV positrons generation for PAS application. Feasibility of this proposal analyzed by G4Beamline and Transport have shown reasonable success. Using 2 Hz, 1.6 GeV, 100 ns and 1.5 μC/bunch proton bunches for bombarding a graphite target, about 100 ns e+ bunches are generated. Quasi-monochromatic positrons in the range of 1-10 MeV included in these bunches have a flux of >107/s, peak brightness of 1014/s. A magnetic-confinement beamline is utilized to transport the positrons and a "Fast Beam Chopper" is unprecedentedly extended to chop those relativistic bunches. The positron beam can be finally characterized by the energy range of 1-10 MeV and bunch width from one hundred ps up to 1 ns. Such ultrashort bunches can be useful in tomography-type positron annihilation spectroscopy (PAS) as well as other applications.

Positron trapping at defects in copper oxide superconductors

NASA Astrophysics Data System (ADS)

McMullen, T.; Jena, P.; Khanna, S. N.; Li, Yi; Jensen, Kjeld O.

1991-05-01

Positron states and lifetimes at defects in the copper oxide superconductors La2-xSrxCuO4, YBa2Cu3O7-x, and Bi2Sr2CaCu2O8+x are calculated with use of the superposed-atom model. In the Bi2Sr2CaCu2O8+x compound, we find that the smaller metal-ion vacancies appear to only bind positrons weakly, while missing oxygens do not trap positrons. In contrast, metal-ion vacancies in La2-xSrxCuO4 and YBa2Cu3O7-x bind positrons by ~1 eV, and oxygen-related defects appear to be the weak-binding sites in these materials. The sites that bind positrons only weakly, by energies ~kBT, are of particular interest in view of the complex temperature dependences of the annihilation characteristics that are observed in these materials.

Defect characterization in Mg-doped GaN studied using a monoenergetic positron beam

NASA Astrophysics Data System (ADS)

Uedono, A.; Ishibashi, S.; Tenjinbayashi, K.; Tsutsui, T.; Nakahara, K.; Takamizu, D.; Chichibu, S. F.

2012-01-01

Vacancy-type defects in Mg-doped GaN grown by metalorganic vapor phase epitaxy were probed using a monoenergetic positron beam. For a sample fabricated with a high H2-flow rate, before post-growth annealing the major defect species detected by positrons was identified as vacancy-clusters. Evidence suggested that other donor-type defects such as nitrogen vacancies also existed. The defects increased the Fermi level position, and enhanced the diffusion of positrons toward the surface. The annihilation of positrons at the top surface was suppressed by Mg-doping. This was attributed to the introduction of a subsurface layer (<6 nm) with a low defect concentration, where the Fermi level position was considered to decrease due to partial activation of Mg. For samples after annealing, the trapping of positrons by residual vacancy-type defects was observed, and the sample crystal quality was found to depend on that before annealing.

Electron and Positron Fluxes in Primary Cosmic Rays Measured with the Alpha Magnetic Spectrometer on the International Space Station

NASA Astrophysics Data System (ADS)

Aguilar, M.; Aisa, D.; Alvino, A.; Ambrosi, G.; Andeen, K.; Arruda, L.; Attig, N.; Azzarello, P.; Bachlechner, A.; Barao, F.; Barrau, A.; Barrin, L.; Bartoloni, A.; Basara, L.; Battarbee, M.; Battiston, R.; Bazo, J.; Becker, U.; Behlmann, M.; Beischer, B.; Berdugo, J.; Bertucci, B.; Bigongiari, G.; Bindi, V.; Bizzaglia, S.; Bizzarri, M.; Boella, G.; de Boer, W.; Bollweg, K.; Bonnivard, V.; Borgia, B.; Borsini, S.; Boschini, M. J.; Bourquin, M.; Burger, J.; Cadoux, F.; Cai, X. D.; Capell, M.; Caroff, S.; Casaus, J.; Cascioli, V.; Castellini, G.; Cernuda, I.; Cervelli, F.; Chae, M. J.; Chang, Y. H.; Chen, A. I.; Chen, H.; Cheng, G. M.; Chen, H. S.; Cheng, L.; Chikanian, A.; Chou, H. Y.; Choumilov, E.; Choutko, V.; Chung, C. H.; Clark, C.; Clavero, R.; Coignet, G.; Consolandi, C.; Contin, A.; Corti, C.; Coste, B.; Cui, Z.; Dai, M.; Delgado, C.; Della Torre, S.; Demirköz, M. B.; Derome, L.; Di Falco, S.; Di Masso, L.; Dimiccoli, F.; Díaz, C.; von Doetinchem, P.; Du, W. J.; Duranti, M.; D'Urso, D.; Eline, A.; Eppling, F. J.; Eronen, T.; Fan, Y. Y.; Farnesini, L.; Feng, J.; Fiandrini, E.; Fiasson, A.; Finch, E.; Fisher, P.; Galaktionov, Y.; Gallucci, G.; García, B.; García-López, R.; Gast, H.; Gebauer, I.; Gervasi, M.; Ghelfi, A.; Gillard, W.; Giovacchini, F.; Goglov, P.; Gong, J.; Goy, C.; Grabski, V.; Grandi, D.; Graziani, M.; Guandalini, C.; Guerri, I.; Guo, K. H.; Habiby, M.; Haino, S.; Han, K. C.; He, Z. H.; Heil, M.; Hoffman, J.; Hsieh, T. H.; Huang, Z. C.; Huh, C.; Incagli, M.; Ionica, M.; Jang, W. Y.; Jinchi, H.; Kanishev, K.; Kim, G. N.; Kim, K. S.; Kirn, Th.; Kossakowski, R.; Kounina, O.; Kounine, A.; Koutsenko, V.; Krafczyk, M. S.; Kunz, S.; La Vacca, G.; Laudi, E.; Laurenti, G.; Lazzizzera, I.; Lebedev, A.; Lee, H. T.; Lee, S. C.; Leluc, C.; Li, H. L.; Li, J. Q.; Li, Q.; Li, Q.; Li, T. X.; Li, W.; Li, Y.; Li, Z. H.; Li, Z. Y.; Lim, S.; Lin, C. H.; Lipari, P.; Lippert, T.; Liu, D.; Liu, H.; Lomtadze, T.; Lu, M. J.; Lu, Y. S.; Luebelsmeyer, K.; Luo, F.; Luo, J. Z.; Lv, S. S.; Majka, R.; Malinin, A.; Mañá, C.; Marín, J.; Martin, T.; Martínez, G.; Masi, N.; Maurin, D.; Menchaca-Rocha, A.; Meng, Q.; Mo, D. C.; Morescalchi, L.; Mott, P.; Müller, M.; Ni, J. Q.; Nikonov, N.; Nozzoli, F.; Nunes, P.; Obermeier, A.; Oliva, A.; Orcinha, M.; Palmonari, F.; Palomares, C.; Paniccia, M.; Papi, A.; Pedreschi, E.; Pensotti, S.; Pereira, R.; Pilo, F.; Piluso, A.; Pizzolotto, C.; Plyaskin, V.; Pohl, M.; Poireau, V.; Postaci, E.; Putze, A.; Quadrani, L.; Qi, X. M.; Rancoita, P. G.; Rapin, D.; Ricol, J. S.; Rodríguez, I.; Rosier-Lees, S.; Rozhkov, A.; Rozza, D.; Sagdeev, R.; Sandweiss, J.; Saouter, P.; Sbarra, C.; Schael, S.; Schmidt, S. M.; Schuckardt, D.; von Dratzig, A. Schulz; Schwering, G.; Scolieri, G.; Seo, E. S.; Shan, B. S.; Shan, Y. H.; Shi, J. Y.; Shi, X. Y.; Shi, Y. M.; Siedenburg, T.; Son, D.; Spada, F.; Spinella, F.; Sun, W.; Sun, W. H.; Tacconi, M.; Tang, C. P.; Tang, X. W.; Tang, Z. C.; Tao, L.; Tescaro, D.; Ting, Samuel C. C.; Ting, S. M.; Tomassetti, N.; Torsti, J.; Türkoǧlu, C.; Urban, T.; Vagelli, V.; Valente, E.; Vannini, C.; Valtonen, E.; Vaurynovich, S.; Vecchi, M.; Velasco, M.; Vialle, J. P.; Wang, L. Q.; Wang, Q. L.; Wang, R. S.; Wang, X.; Wang, Z. X.; Weng, Z. L.; Whitman, K.; Wienkenhöver, J.; Wu, H.; Xia, X.; Xie, M.; Xie, S.; Xiong, R. Q.; Xin, G. M.; Xu, N. S.; Xu, W.; Yan, Q.; Yang, J.; Yang, M.; Ye, Q. H.; Yi, H.; Yu, Y. J.; Yu, Z. Q.; Zeissler, S.; Zhang, J. H.; Zhang, M. T.; Zhang, X. B.; Zhang, Z.; Zheng, Z. M.; Zhuang, H. L.; Zhukov, V.; Zichichi, A.; Zimmermann, N.; Zuccon, P.; Zurbach, C.; AMS Collaboration

2014-09-01

Precision measurements by the Alpha Magnetic Spectrometer on the International Space Station of the primary cosmic-ray electron flux in the range 0.5 to 700 GeV and the positron flux in the range 0.5 to 500 GeV are presented. The electron flux and the positron flux each require a description beyond a single power-law spectrum. Both the electron flux and the positron flux change their behavior at ˜30 GeV but the fluxes are significantly different in their magnitude and energy dependence. Between 20 and 200 GeV the positron spectral index is significantly harder than the electron spectral index. The determination of the differing behavior of the spectral indices versus energy is a new observation and provides important information on the origins of cosmic-ray electrons and positrons.

Origin of the positron excess in cosmic rays.

PubMed

Blasi, Pasquale

2009-07-31

We show that the positron excess measured by the PAMELA experiment in the region between 10 and 100 GeV may well be a natural consequence of the standard scenario for the origin of Galactic cosmic rays. The "excess" arises because of positrons created as secondary products of hadronic interactions inside the sources, but the crucial physical ingredient which leads to a natural explanation of the positron flux is the fact that the secondary production takes place in the same region where cosmic rays are being accelerated. Therefore secondary positrons (and electrons) participate in the acceleration process and turn out to have a very flat spectrum, which is responsible, after propagation in the Galaxy, for the observed positron excess. This effect cannot be avoided though its strength depends on the values of the environmental parameters during the late stages of evolution of supernova remnants.

Determination of interfacial states in solid heterostructures using a variable-energy positron beam

DOEpatents

Asoka kumar, Palakkal P. V.; Lynn, Kelvin G.

1993-01-01

A method and means is provided for characterizing interfacial electron states in solid heterostructures using a variable energy positron beam to probe the solid heterostructure. The method includes the steps of directing a positron beam having a selected energy level at a point on the solid heterostructure so that the positron beam penetrates into the solid heterostructure and causes positrons to collide with the electrons at an interface of the solid heterostructure. The number and energy of gamma rays emitted from the solid heterostructure as a result of the annihilation of positrons with electrons at the interface are detected. The data is quantified as a function of the Doppler broadening of the photopeak about the 511 keV line created by the annihilation of the positrons and electrons at the interface, preferably, as an S-parameter function; and a normalized S-parameter function of the data is obtained. The function of data obtained is compared with a corresponding function of the Doppler broadening of the annihilation photopeak about 511 keV for a positron beam having a second energy level directed at the same material making up a portion of the solid heterostructure. The comparison of these functions facilitates characterization of the interfacial states of electrons in the solid heterostructure at points corresponding to the penetration of positrons having the particular energy levels into the interface of the solid heterostructure. Accordingly, the invention provides a variable-energy non-destructive probe of solid heterostructures, such as SiO.sub.2 /Si, MOS or other semiconductor devices.

Determination of interfacial states in solid heterostructures using a variable-energy positron beam

DOEpatents

Asokakumar, P.P.V.; Lynn, K.G.

1993-04-06

A method and means is provided for characterizing interfacial electron states in solid heterostructures using a variable energy positron beam to probe the solid heterostructure. The method includes the steps of directing a positron beam having a selected energy level at a point on the solid heterostructure so that the positron beam penetrates into the solid heterostructure and causes positrons to collide with the electrons at an interface of the solid heterostructure. The number and energy of gamma rays emitted from the solid heterostructure as a result of the annihilation of positrons with electrons at the interface are detected. The data is quantified as a function of the Doppler broadening of the photopeak about the 511 keV line created by the annihilation of the positrons and electrons at the interface, preferably, as an S-parameter function; and a normalized S-parameter function of the data is obtained. The function of data obtained is compared with a corresponding function of the Doppler broadening of the annihilation photopeak about 511 keV for a positron beam having a second energy level directed at the same material making up a portion of the solid heterostructure. The comparison of these functions facilitates characterization of the interfacial states of electrons in the solid heterostructure at points corresponding to the penetration of positrons having the particular energy levels into the interface of the solid heterostructure. Accordingly, the invention provides a variable-energy non-destructive probe of solid heterostructures, such as SiO[sub 2]/Si, MOS or other semiconductor devices.

Modular Apparatus and Method for Attaching Multiple Devices

NASA Technical Reports Server (NTRS)

Okojie, Robert S (Inventor)

2015-01-01

A modular apparatus for attaching sensors and electronics is disclosed. The modular apparatus includes a square recess including a plurality of cavities and a reference cavity such that a pressure sensor can be connected to the modular apparatus. The modular apparatus also includes at least one voltage input hole and at least one voltage output hole operably connected to each of the plurality of cavities such that voltage can be applied to the pressure sensor and received from the pressure sensor.

Robotic hand with modular extensions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salisbury, Curt Michael; Quigley, Morgan

A robotic device is described herein. The robotic device includes a frame that comprises a plurality of receiving regions that are configured to receive a respective plurality of modular robotic extensions. The modular robotic extensions are removably attachable to the frame at the respective receiving regions by way of respective mechanical fuses. Each mechanical fuse is configured to trip when a respective modular robotic extension experiences a predefined load condition, such that the respective modular robotic extension detaches from the frame when the load condition is met.

A novel radiochemical approach to 1-(2'-deoxy-2'-[(18) F]fluoro-β-d-arabinofuranosyl)cytosine ((18) F-FAC).

PubMed

Meyer, Jan-Philip; Probst, Katrin C; Trist, Iuni M L; McGuigan, Christopher; Westwell, Andrew D

2014-09-01

(18) F-FAC (1-(2'-deoxy-2'-[(18) F]fluoro-β-D-arabinofuranosyl)-cytosine) is an important 2'-fluoro-nucleoside-based positron emission tomography (PET) tracer that has been used for in vivo prediction of response to the widely used cancer chemotherapy drug gemcitabine. Previously reported synthetic routes to (18) F-FAC have relied on early introduction of the (18) F radiolabel prior to attachment to protected cytosine base. Considering the (18) F radiochemical half-life (110 min) and the technical challenges of multi-step syntheses on PET radiochemistry modular systems, late-stage radiofluorination is preferred for reproducible and reliable radiosynthesis with in vivo applications. Herein, we report the first late-stage radiosynthesis of (18) F-FAC. Cytidine derivatives with leaving groups at the 2'-position are particularly prone to undergo anhydro side-product formation upon heating because of their electron density at the 2-carbonyl pyrimidone oxygen. Our rationally developed fluorination precursor showed an improved reactivity-to-stability ratio at elevated temperatures. (18) F-FAC was obtained in radiochemical yields of 4.3-5.5% (n = 8, decay-corrected from end of bombardment), with purities ≥98% and specific activities ≥63 GBq/µmol. The synthesis time was 168 min. Copyright © 2014 John Wiley & Sons, Ltd.

The VISPA Internet Platform for Students

NASA Astrophysics Data System (ADS)

Asseldonk, D. v.; Erdmann, M.; Fischer, R.; Glaser, C.; Müller, G.; Quast, T.; Rieger, M.; Urban, M.

2016-04-01

The VISPA internet platform enables users to remotely run Python scripts and view resulting plots or inspect their output data. With a standard web browser as the only user requirement on the client-side, the system becomes suitable for blended learning approaches for university physics students. VISPA was used in two consecutive years each by approx. 100 third year physics students at the RWTH Aachen University for their homework assignments. For example, in one exercise students gained a deeper understanding of Einsteins mass-energy relation by analyzing experimental data of electron-positron pairs revealing J / Ψ and Z particles. Because the students were free to choose their working hours, only few users accessed the platform simultaneously. The positive feedback from students and the stability of the platform lead to further development of the concept. This year, students accessed the platform in parallel while they analyzed the data recorded by demonstrated experiments live in the lecture hall. The platform is based on experience in the development of professional analysis tools. It combines core technologies from previous projects: an object-oriented C++ library, a modular data-driven analysis flow, and visual analysis steering. We present the platform and discuss its benefits in the context of teaching based on surveys that are conducted each semester.

Investigations of coastal zones using a modular amphibious vehicle

NASA Astrophysics Data System (ADS)

Zeziulin, Denis; Makarov, Vladimir; Filatov, Valery; Beresnev, Pavel; Belyakov, Vladimir; Kurkin, Andrey

2017-04-01

The project aims to develop a means of verification of data on sea excitement derived from Autonomous mobile robotic system (AMRS) for coastal monitoring and forecasting marine natural disasters [Kurkin A., Pelinovsky E., Tyugin D., Giniyatullin A., Kurkina O., Belyakov V., Makarov V., Zeziulin D., Kuznetsov K. Autonomous Robotic System for Coastal Monitoring // Proceedings of the 12th International Conference on the Mediterranean Coastal Environment MEDCOAST. 2015. V. 2. P. 933-944]. The chassis of the developed remote-controlled modular amphibious vehicle (MAV) will be equipped with a video camera and a hydrostatic wave-plotting device with strings sensors mounted on the stationary body's supports. To track the position of the MAV there will be installed the navigation system in order to correct the measurement data. The peculiarity of the tricycle MAV is the ability to change its geometric parameters that will increase its stability to actions of destructive waves and mobility. In May-June 2016 authors took part in conducting field tests of the AMRS on the Gulf of Mordvinov (Sea of Okhotsk, Sakhalin Island). Participation in this expedition contributed to obtaining experimental data on the topography and the physical and mechanical properties of the surf zone of the most promising field of using the MAV as a road for its moving. Within the project there was developed a mathematical model of the MAV motion in coastal conditions taking into account the new analytical dependences describing the physical and mechanical characteristics of the ground surfaces and the landscape, as well as hydrodynamic effects of surf zones. The reasonable selection of rational parameters of the MAV and developing the methodology of creating effective vehicles for investigations of specific coastal areas of the Okhotsk Sea will be made by using the mathematical model.

Positron lifetime calculation for the elements of the periodic table.

PubMed

Campillo Robles, J M; Ogando, E; Plazaola, F

2007-04-30

Theoretical positron lifetime values have been calculated systematically for most of the elements of the periodic table. Self-consistent and non-self-consistent schemes have been used for the calculation of the electronic structure in the solid, as well as different parametrizations for the positron enhancement factor and correlation energy. The results obtained have been studied and compared with experimental data, confirming the theoretical trends. As is known, positron lifetimes in bulk show a periodic behaviour with atomic number. These calculations also confirm that monovacancy lifetimes follow the same behaviour. The effects of enhancement factors used in calculations have been commented upon. Finally, we have analysed the effects that f and d electrons have on positron lifetimes.

Positron lifetime studies of defect structures in Ba(1-x)K(x)BiO3

NASA Astrophysics Data System (ADS)

Obrien, J. C.; Howell, R. H.; Radousky, H. B.; Sterne, P. A.; Hinks, D. G.; Folkerts, T. J.; Shelton, R. N.

1990-12-01

Temperature-dependent positron lifetime experiments have been performed from room temperature to cryogenic temperatures on Ba(1-x)K(x)BiO3, for x = 0.4 and 0.5. From the temperature dependence of the positron lifetime in the normal state, we observe a clear signature of competition between separate defect populations to trap the positron. Theoretical calculations of lifetimes of free or trapped positrons have been performed on Ba(1-x)K(x)BiO3, to help identify these defects. Lifetime measurements separated by long times have been performed and evidence of aging effects in the sample defect populations is seen in these materials.

Account of the intratrack radiolytic processes for interpretation of the AMOC spectrum of liquid water

NASA Astrophysics Data System (ADS)

Zvezhinskiy, D. S.; Butterling, M.; Wagner, A.; Krause-Rehberg, R.; Stepanov, S. V.

2013-06-01

Recent development of the Gamma-induced Positron Spectroscopy (GiPS) setup significantly extends applicability of the Age-Momentum Correlation technique (AMOC) for studies of the bulk samples. It also provides many advantages comparing with conventional positron annihilation experiments in liquids, such as extremely low annihilation fraction in vessel walls, absence of a positron source and positron annihilations in it. We have developed a new approach for processing and interpretation of the AMOC-GiPS data based on the diffusion recombination model of the intratrack radiolytic processes. This approach is verified in case of liquid water, which is considered as a reference medium in the positron and positronium chemistry.

Modular femoral neck fracture after primary total hip arthroplasty.

PubMed

Sotereanos, Nicholas G; Sauber, Timothy J; Tupis, Todd T

2013-01-01

The use of modular femoral stems in primary total hip arthroplasty has increased considerably in recent years. These modular components offer the surgeon the ability to independently alter version, offset, and length of the femoral component of a hip arthroplasty. This increases the surgeon's ability to accurately recreate the relevant anatomy but increases the possibilities of corrosion and fracture. Multiple case reports have highlighted fractures of these modular components. We present a case of a fracture of a modular design that has had no previously reported modular neck fractures. The patient was informed that data concerning the case would be submitted, and he consented. Copyright © 2013 Elsevier Inc. All rights reserved.

Positron lifetime setup based on DRS4 evaluation board

NASA Astrophysics Data System (ADS)

Petriska, M.; Sojak, S.; Slugeň, V.

2014-04-01

A digital positron lifetime setup based on DRS4 evaluation board designed at the Paul Scherrer Institute has been constructed and tested in the Positron annihilation laboratory Slovak University of Technology Bratislava. The high bandwidth, low power consumption and short readout time make DRS4 chip attractive for positron annihilation lifetime (PALS) setup, replacing traditional ADCs and TDCs. A software for PALS setup online and offline pulse analysis was developed with Qt,Qwt and ALGLIB libraries.

The metabolism of the human brain studied with positron emission tomography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greitz, T.; Ingvar, D.H.; Widen, L.

1985-01-01

This volume presents coverage of the use of positron emission tomography (PET) to study the human brain. The contributors assess new developments in high-resolution positron emission tomography, cyclotrons, radiochemistry, and tracer kinetic models, and explore the use of PET in brain energy metabolism, blood flow, and protein synthesis measurements, receptor analysis, and pH determinations, In addition, they discuss the relevance and applications of positron emission tomography from the perspectives of physiology, neurology, and psychiatry.

Measurements of the absolute energy spectra of cosmic-ray positrons and electrons above 7 GeV

NASA Astrophysics Data System (ADS)

Grimani, C.; Stephens, S. A.; Cafagna, F. S.; Basini, G.; Bellotti, R.; Brunetti, M. T.; Circella, M.; Codino, A.; De Marzo, C.; De Pascale, M. P.; Finetti, N.; Golden, R. L.; Hof, M.; Menn, W.; Mitchell, J. W.; Morselli, A.; Ormes, J. F.; Papini, P.; Pfeifer, C.; Piccardi, S.; Picozza, P.; Ricci, M.; Simon, M.; Spillantini, P.; Stochaj, S. J.; Streitmatter, R. E.

2002-09-01

A measurement of the energy spectra of cosmic-ray positrons and electrons was made with a balloon-borne magnet-spectrometer, which was flown at a mean geomagnetic cut-off of 4.5 GV/c. The observed positron flux in the energy range 7-16 GeV is approximately an order of magnitude lower than that of electrons, as measured in other experiments at various energies. The power law spectral index of the observed differential energy spectrum of electrons is -2.89 +/- 0.10 in the energy interval 7.5-47 GeV. For positrons the overall fit of the available data above 7 GeV has been considered. The spectral index is found to be -3.37 +/- 0.26 and the fraction of positrons, e+/(e+,+ e-), has a mean value of 0.064 +/- 0.003. The world data on e+/(e+,+ e-) from 0.1 to 30 GeV indicate that a plerion type electron spectrum is preferred over the other types. The trend of the presently existing high energy data also suggests a possible contribution of positrons produced at the pulsar polar cap. High resolution experiments capable of identifying positrons at least up to 100 GeV with high statistics are required to pinpoint the origin of both electrons and positrons in the cosmic radiation.

Intense positron beam as a source for production of electron-positron plasma

NASA Astrophysics Data System (ADS)

Stoneking, M. R.; Horn-Stanja, J.; Stenson, E. V.; Pedersen, T. Sunn; Saitoh, H.; Hergenhahn, U.; Niemann, H.; Paschkowski, N.; Hugenschmidt, C.; Piochacz, C.

2016-10-01

We aim to produce magnetically confined, short Debye length electron-positron plasma and test predicted properties for such systems. A first challenge is obtaining large numbers of positrons; a table-top experiment (system size 5 cm) with a temperature less than 5 eV requires about 1010 positrons to have more than 10 Debye lengths in the system. The NEPOMUC facility at the FRM II research reactor in Germany is one of the world's most intense positron sources. We report on characterization (using a retarding field energy analyzer with magnetic field gradient) of the NEPOMUC beam as delivered to the open beam port at various beam energies and in both the re-moderated and primary beam configurations in order to design optimal trapping (and accumulation) schemes for production of electron-positron plasma. The intensity of the re-moderated (primary) beam is in the range 2 -3 x 107 /s (1 - 5 x 108 /s). The re-moderated beam is currently the most promising for direct injection and confinement experiments; it has a parallel energy spread of 15 - 35% and the transverse energy spread is 6 - 15% of the parallel energy. We report on the implications for injection and trapping in a dipole magnetic field as well as plans for beam development, in situ re-moderation, and accumulation. We also report results demonstrating a difference in phosphor luminescent response to low energy positrons versus electrons.

The Effects of Surface Reconstruction and Electron-Positron Correlation on the Annihilation Characteristics of Positrons Trapped at Semiconductor Surfaces

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Jung, E.; Weiss, A. H.

2009-03-01

Experimental positron annihilation induced Auger electron spectroscopy (PAES) data from Ge(100) and Ge(111) surfaces display several strong Auger peaks corresponding to M4,5N1N2,3, M2,3M4,5M4,5, M2,3M4,5V, and M1M4,5M4,5 Auger transitions. The integrated peak intensities of Auger transitions have been used to obtain experimental annihilation probabilities for the Ge 3d and 3p core electrons. The experimental data were analyzed by performing theoretical studies of the effects of surface reconstructions and electron-positron correlations on image potential induced surface states and annihilation characteristics of positrons trapped at the reconstructed Ge(100) and Ge(111) surfaces. Calculations of positron surface states and annihilation characteristics have been performed for Ge(100) surface with (2×1), (2×2), and (4×2) reconstructions, and for Ge(111) surface with c(2×8) reconstruction. Estimates of the positron binding energy and annihilation characteristics reveal their sensitivity to the specific atomic structure of the topmost layers of the semiconductor and to the approximations used to describe electron-positron correlations. The results of these theoretical studies are compared with the ones obtained for the reconstructed Si(100)-(2×1) and Si(111)-(7×7) surfaces.

Positron Annihilation Induced Auger Electron Spectroscopic Studies Of Reconstructed Semiconductor Surfaces

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Reed, J. A.; Starnes, S. G.; Weiss, A. H.

2011-06-01

The positron annihilation induced Auger spectrum from GaAs(100) displays six As and three Ga Auger peaks below 110 eV corresponding to M4,5VV, M2M4V, M2,3M4,5M4,5 Auger transitions for As and M2,3M4,5M4,5 Auger transitions for Ga. The integrated Auger peak intensities have been used to obtain experimental annihilation probabilities of surface trapped positrons with As 3p and 3d and Ga 3p core level electrons. PAES data is analyzed by performing calculations of positron surface and bulk states and annihilation characteristics of surface trapped positrons with relevant Ga and As core level electrons for both Ga- and As-rich (100) surfaces of GaAs, ideally terminated, non-reconstructed and with (2×8), (2×4), and (4×4) reconstructions. The orientation-dependent variations of the atomic and electron densities associated with reconstructions are found to affect localization of the positron wave function at the surface. Computed positron binding energy, work function, and annihilation characteristics demonstrate their sensitivity both to chemical composition and atomic structure of the topmost layers of the surface. Theoretical annihilation probabilities of surface trapped positrons with As 3d, 3p, and Ga 3p core level electrons are compared with the ones estimated from the measured Auger peak intensities.

Positron annihilation in SiO 2-Si studied by a pulsed slow positron beam

NASA Astrophysics Data System (ADS)

Suzuki, R.; Ohdaira, T.; Uedono, A.; Kobayashi, Y.

2002-06-01

Positron and positronium (Ps) behavior in SiO 2-Si have been studied by means of positron annihilation lifetime spectroscopy (PALS) and age-momentum correlation (AMOC) spectroscopy with a pulsed slow positron beam. The PALS study of SiO 2-Si samples, which were prepared by a dry-oxygen thermal process, revealed that the positrons implanted in the Si substrate and diffused back to the interface do not contribute to the ortho-Ps long-lived component, and the lifetime spectrum of the interface has at least two components. From the AMOC study, the momentum distribution of the ortho-Ps pick-off annihilation in SiO 2, which shows broader momentum distribution than that of crystalline Si, was found to be almost the same as that of free positron annihilation in SiO 2. A varied interface model was proposed to interpret the results of the metal-oxide-semiconductor (MOS) experiments. The narrow momentum distribution found in the n-type MOS with a negative gate bias voltage could be attributed to Ps formation and rapid spin exchange in the SiO 2-Si interface. We have developed a two-dimensional positron lifetime technique, which measures annihilation time and pulse height of the scintillation gamma-ray detector for each event. Using this technique, the positronium behavior in a porous SiO 2 film, grown by a sputtering method, has been studied.

Positron deep level transient spectroscopy — a new application of positron annihilation to semiconductor physics

NASA Astrophysics Data System (ADS)

Beling, C. D.; Fung, S.; Au, H. L.; Ling, C. C.; Reddy, C. V.; Deng, A. H.; Panda, B. K.

1997-05-01

Recent positron mobility and lifetime measurements made on ac-biased metal on semi-insulating GaAs junctions, which have identified the native EL2 defect through a determination of the characteristic ionization energy of the donor level, are reviewed. It is shown that these measurements point towards a new spectroscopy, tentatively named positron-DLTS (deep level transient spectroscopy), that is the direct complement to conventional DLTS in that it monitors transients in the electric field of the depletion region rather than the inversely related depletion width, as deep levels undergo ionization. In this new spectroscopy, which may be applied to doped material by use of a suitable positron beam, electric field transients are monitored through the Doppler shift of the annihilation radiation resulting from the drift velocity of the positron in the depletion region. Two useful extensions of the new spectroscopy beyond conventional capacitance-DLTS are suggested. The first is that in some instances information on the microstructure of the defect causing the deep level may be inferred from the sensitivity of the positron to vacancy defects of negative and neutral charge states. The second is that the positron annihilation technique is intrinsically much faster than conventional DLTS with the capability of observing transients some 10 6 times faster, thus allowing deep levels (and even shallow levels) to be investigated without problems associated with carrier freeze-out.

Modular properties of 6d (DELL) systems

NASA Astrophysics Data System (ADS)

Aminov, G.; Mironov, A.; Morozov, A.

2017-11-01

If super-Yang-Mills theory possesses the exact conformal invariance, there is an additional modular invariance under the change of the complex bare charge [InlineMediaObject not available: see fulltext.]. The low-energy Seiberg-Witten prepotential ℱ( a), however, is not explicitly invariant, because the flat moduli also change a - → a D = ∂ℱ/∂ a. In result, the prepotential is not a modular form and depends also on the anomalous Eisenstein series E 2. This dependence is usually described by the universal MNW modular anomaly equation. We demonstrate that, in the 6 d SU( N) theory with two independent modular parameters τ and \\widehat{τ} , the modular anomaly equation changes, because the modular transform of τ is accompanied by an ( N -dependent!) shift of \\widehat{τ} and vice versa. This is a new peculiarity of double-elliptic systems, which deserves further investigation.

Towards a Formal Basis for Modular Safety Cases

NASA Technical Reports Server (NTRS)

Denney, Ewen; Pai, Ganesh

2015-01-01

Safety assurance using argument-based safety cases is an accepted best-practice in many safety-critical sectors. Goal Structuring Notation (GSN), which is widely used for presenting safety arguments graphically, provides a notion of modular arguments to support the goal of incremental certification. Despite the efforts at standardization, GSN remains an informal notation whereas the GSN standard contains appreciable ambiguity especially concerning modular extensions. This, in turn, presents challenges when developing tools and methods to intelligently manipulate modular GSN arguments. This paper develops the elements of a theory of modular safety cases, leveraging our previous work on formalizing GSN arguments. Using example argument structures we highlight some ambiguities arising through the existing guidance, present the intuition underlying the theory, clarify syntax, and address modular arguments, contracts, well-formedness and well-scopedness of modules. Based on this theory, we have a preliminary implementation of modular arguments in our toolset, AdvoCATE.

Brain modularity controls the critical behavior of spontaneous activity.

PubMed

Russo, R; Herrmann, H J; de Arcangelis, L

2014-03-13

The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often modify this structure. An important open question concerns the role of brain modularity in sustaining the critical behaviour of spontaneous activity. Here we analyse the neuronal activity of a model, successful in reproducing on non-modular networks the scaling behaviour observed in experimental data, on a modular network implementing the main statistical features measured in human brain. We show that on a modular network, regardless the strength of the synaptic connections or the modular size and number, activity is never fully scale-free. Neuronal avalanches can invade different modules which results in an activity depression, hindering further avalanche propagation. Critical behaviour is solely recovered if inter-module connections are added, modifying the modular into a more random structure.

Plasma Wakefield Acceleration of an Intense Positron Beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blue, B

2004-04-21

The Plasma Wakefield Accelerator (PWFA) is an advanced accelerator concept which possess a high acceleration gradient and a long interaction length for accelerating both electrons and positrons. Although electron beam-plasma interactions have been extensively studied in connection with the PWFA, very little work has been done with respect to positron beam-plasma interactions. This dissertation addresses three issues relating to a positron beam driven plasma wakefield accelerator. These issues are (a) the suitability of employing a positron drive bunch to excite a wake; (b) the transverse stability of the drive bunch; and (c) the acceleration of positrons by the plasma wakemore » that is driven by a positron bunch. These three issues are explored first through computer simulations and then through experiments. First, a theory is developed on the impulse response of plasma to a short drive beam which is valid for small perturbations to the plasma density. This is followed up with several particle-in-cell (PIC) simulations which study the experimental parameter (bunch length, charge, radius, and plasma density) range. Next, the experimental setup is described with an emphasis on the equipment used to measure the longitudinal energy variations of the positron beam. Then, the transverse dynamics of a positron beam in a plasma are described. Special attention is given to the way focusing, defocusing, and a tilted beam would appear to be energy variations as viewed on our diagnostics. Finally, the energy dynamics imparted on a 730 {micro}m long, 40 {micro}m radius, 28.5 GeV positron beam with 1.2 x 10{sup 10} particles in a 1.4 meter long 0-2 x 10{sup 14} e{sup -}/cm{sup 3} plasma is described. First the energy loss was measured as a function of plasma density and the measurements are compared to theory. Then, an energy gain of 79 {+-} 15 MeV is shown. This is the first demonstration of energy gain of a positron beam in a plasma and it is in good agreement with the predictions made by the 3-D PIC code. The work presented in this dissertation will show that plasma wakefield accelerators are an attractive technology for future particle accelerators.« less

Why Go Modular? A Review of Modular A-Level Mathematics.

ERIC Educational Resources Information Center

Taverner, Sally; Wright, Martin

1997-01-01

Attitudes, academic intentions, and attainment of students gaining a grade in A-level (Advanced level) mathematics were compared for those who followed a modular course and those assessed at the end of two years of study. Overall, the final grades of those assessed modularly were half a grade higher. (JOW)

On Classification of Modular Categories by Rank: Table A.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bruillard, Paul; Ng, Siu-Hung; Rowell, Eric C.

2016-04-10

The feasibility of a classification-by-rank program for modular categories follows from the Rank-Finiteness Theorem. We develop arithmetic, representation theoretic and algebraic methods for classifying modular categories by rank. As an application, we determine all possible fusion rules for all rank=5 modular categories and describe the corresponding monoidal equivalence classes.

46 CFR 181.450 - Independent modular smoke detecting units.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 7 2013-10-01 2013-10-01 false Independent modular smoke detecting units. 181.450... Independent modular smoke detecting units. (a) An independent modular smoke detecting unit must: (1) Meet UL 217 (incorporated by reference, see 46 CFR 175.600) and be listed as a “Single Station Smoke detector...

46 CFR 181.450 - Independent modular smoke detecting units.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 7 2012-10-01 2012-10-01 false Independent modular smoke detecting units. 181.450... Independent modular smoke detecting units. (a) An independent modular smoke detecting unit must: (1) Meet UL 217 (incorporated by reference, see 46 CFR 175.600) and be listed as a “Single Station Smoke detector...

46 CFR 181.450 - Independent modular smoke detecting units.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 7 2011-10-01 2011-10-01 false Independent modular smoke detecting units. 181.450... Independent modular smoke detecting units. (a) An independent modular smoke detecting unit must: (1) Meet UL 217 (incorporated by reference, see 46 CFR 175.600) and be listed as a “Single Station Smoke detector...

46 CFR 181.450 - Independent modular smoke detecting units.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Independent modular smoke detecting units. 181.450... Independent modular smoke detecting units. (a) An independent modular smoke detecting unit must: (1) Meet UL 217 (incorporated by reference, see 46 CFR 175.600) and be listed as a “Single Station Smoke detector...

46 CFR 181.450 - Independent modular smoke detecting units.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 7 2014-10-01 2014-10-01 false Independent modular smoke detecting units. 181.450... Independent modular smoke detecting units. (a) An independent modular smoke detecting unit must: (1) Meet UL 217 (incorporated by reference, see 46 CFR 175.600) and be listed as a “Single Station Smoke detector...

Ionisation of atomic hydrogen by positron impact

NASA Technical Reports Server (NTRS)

Spicher, Gottfried; Olsson, Bjorn; Raith, Wilhelm; Sinapius, Guenther; Sperber, Wolfgang

1990-01-01

With the crossed beam apparatus the relative impact-ionization cross section of atomic hydrogen by positron impact was measured. A layout of the scattering region is given. The first measurements on the ionization of atomic hydrogen by positron impact are also given.

Unraveling the disease consequences and mechanisms of modular structure in animal social networks

PubMed Central

Leu, Stephan T.; Cross, Paul C.; Hudson, Peter J.; Bansal, Shweta

2017-01-01

Disease risk is a potential cost of group living. Although modular organization is thought to reduce this cost in animal societies, empirical evidence toward this hypothesis has been conflicting. We analyzed empirical social networks from 43 animal species to motivate our study of the epidemiological consequences of modular structure in animal societies. From these empirical studies, we identified the features of interaction patterns associated with network modularity and developed a theoretical network model to investigate when and how subdivisions in social networks influence disease dynamics. Contrary to prior work, we found that disease risk is largely unaffected by modular structure, although social networks beyond a modular threshold experience smaller disease burden and longer disease duration. Our results illustrate that the lowering of disease burden in highly modular social networks is driven by two mechanisms of modular organization: network fragmentation and subgroup cohesion. Highly fragmented social networks with cohesive subgroups are able to structurally trap infections within a few subgroups and also cause a structural delay to the spread of disease outbreaks. Finally, we show that network models incorporating modular structure are necessary only when prior knowledge suggests that interactions within the population are highly subdivided. Otherwise, null networks based on basic knowledge about group size and local contact heterogeneity may be sufficient when data-limited estimates of epidemic consequences are necessary. Overall, our work does not support the hypothesis that modular structure universally mitigates the disease impact of group living. PMID:28373567

Unraveling the disease consequences and mechanisms of modular structure in animal social networks

USGS Publications Warehouse

Sah, Pratha; Leu, Stephan T.; Cross, Paul C.; Hudson, Peter J.; Bansal, Shweta

2017-01-01

Disease risk is a potential cost of group living. Although modular organization is thought to reduce this cost in animal societies, empirical evidence toward this hypothesis has been conflicting. We analyzed empirical social networks from 43 animal species to motivate our study of the epidemiological consequences of modular structure in animal societies. From these empirical studies, we identified the features of interaction patterns associated with network modularity and developed a theoretical network model to investigate when and how subdivisions in social networks influence disease dynamics. Contrary to prior work, we found that disease risk is largely unaffected by modular structure, although social networks beyond a modular threshold experience smaller disease burden and longer disease duration. Our results illustrate that the lowering of disease burden in highly modular social networks is driven by two mechanisms of modular organization: network fragmentation and subgroup cohesion. Highly fragmented social networks with cohesive subgroups are able to structurally trap infections within a few subgroups and also cause a structural delay to the spread of disease outbreaks. Finally, we show that network models incorporating modular structure are necessary only when prior knowledge suggests that interactions within the population are highly subdivided. Otherwise, null networks based on basic knowledge about group size and local contact heterogeneity may be sufficient when data-limited estimates of epidemic consequences are necessary. Overall, our work does not support the hypothesis that modular structure universally mitigates the disease impact of group living.

Unraveling the disease consequences and mechanisms of modular structure in animal social networks.

PubMed

Sah, Pratha; Leu, Stephan T; Cross, Paul C; Hudson, Peter J; Bansal, Shweta

2017-04-18

Disease risk is a potential cost of group living. Although modular organization is thought to reduce this cost in animal societies, empirical evidence toward this hypothesis has been conflicting. We analyzed empirical social networks from 43 animal species to motivate our study of the epidemiological consequences of modular structure in animal societies. From these empirical studies, we identified the features of interaction patterns associated with network modularity and developed a theoretical network model to investigate when and how subdivisions in social networks influence disease dynamics. Contrary to prior work, we found that disease risk is largely unaffected by modular structure, although social networks beyond a modular threshold experience smaller disease burden and longer disease duration. Our results illustrate that the lowering of disease burden in highly modular social networks is driven by two mechanisms of modular organization: network fragmentation and subgroup cohesion. Highly fragmented social networks with cohesive subgroups are able to structurally trap infections within a few subgroups and also cause a structural delay to the spread of disease outbreaks. Finally, we show that network models incorporating modular structure are necessary only when prior knowledge suggests that interactions within the population are highly subdivided. Otherwise, null networks based on basic knowledge about group size and local contact heterogeneity may be sufficient when data-limited estimates of epidemic consequences are necessary. Overall, our work does not support the hypothesis that modular structure universally mitigates the disease impact of group living.

Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

PubMed Central

del Sol, Antonio; Araúzo-Bravo, Marcos J; Amoros, Dolors; Nussinov, Ruth

2007-01-01

Background Allosteric communications are vital for cellular signaling. Here we explore a relationship between protein architectural organization and shortcuts in signaling pathways. Results We show that protein domains consist of modules interconnected by residues that mediate signaling through the shortest pathways. These mediating residues tend to be located at the inter-modular boundaries, which are more rigid and display a larger number of long-range interactions than intra-modular regions. The inter-modular boundaries contain most of the residues centrally conserved in the protein fold, which may be crucial for information transfer between amino acids. Our approach to modular decomposition relies on a representation of protein structures as residue-interacting networks, and removal of the most central residue contacts, which are assumed to be crucial for allosteric communications. The modular decomposition of 100 multi-domain protein structures indicates that modules constitute the building blocks of domains. The analysis of 13 allosteric proteins revealed that modules characterize experimentally identified functional regions. Based on the study of an additional functionally annotated dataset of 115 proteins, we propose that high-modularity modules include functional sites and are the basic functional units. We provide examples (the Gαs subunit and P450 cytochromes) to illustrate that the modular architecture of active sites is linked to their functional specialization. Conclusion Our method decomposes protein structures into modules, allowing the study of signal transmission between functional sites. A modular configuration might be advantageous: it allows signaling proteins to expand their regulatory linkages and may elicit a broader range of control mechanisms either via modular combinations or through modulation of inter-modular linkages. PMID:17531094

Modular assembly for supporting, straining, and directing flow to a core in a nuclear reactor

DOEpatents

Pennell, William E.

1977-01-01

A reactor core support arrangement for supporting, straining, and providing fluid flow to the core and periphery of a nuclear reactor during normal operation. A plurality of removable inlet modular units are contained within permanent liners in the lower supporting plate of the reactor vessel lower internals. During normal operation (1) each inlet modular unit directs main coolant flow to a plurality of core assemblies, the latter being removably supported in receptacles in the upper portion of the modular unit and (2) each inlet modular unit may direct bypass flow to a low pressure annular region of the reactor vessel. Each inlet modular unit may include special fluid seals interposed between mating surfaces of the inlet modular units and the core assemblies and between the inlet modular units and the liners, to minimize leakage and achieve an hydraulic balance. Utilizing the hydraulic balance, the modular units are held in the liners and the assemblies are held in the modular unit receptacles by their own respective weight. Included as part of the permanent liners below the horizontal support plate are generally hexagonal axial debris barriers. The axial debris barriers collectively form a bottom boundary of a secondary high pressure plenum, the upper boundary of which is the bottom surface of the horizontal support plate. Peripheral liners include radial debris barriers which collectively form a barrier against debris entry radially. During normal operation primary coolant inlet openings in the liner, below the axial debris barriers, pass a large amount of coolant into the inlet modular units, and secondary coolant inlet openings in the portion of the liners within the secondary plenum pass a small amount of coolant into the inlet modular units. The secondary coolant inlet openings also provide alternative coolant inlet flow paths in the unlikely event of blockage of the primary inlet openings. The primary inlet openings have characteristics which limit the entry of debris and minimize the potential for debris entering the primary inlets blocking the secondary inlets from inside the modular unit.

Positron spectroscopy of 2D materials using an advanced high intensity positron beam

NASA Astrophysics Data System (ADS)

McDonald, A.; Chirayath, V.; Lim, Z.; Gladen, R.; Chrysler, M.; Fairchild, A.; Koymen, A.; Weiss, A.

An advanced high intensity variable energy positron beam(~1eV to 20keV) has been designed, tested and utilized for the first coincidence Doppler broadening (CDB) measurements on 6-8 layers graphene on polycrystalline Cu sample. The system is capable of simultaneous Positron annihilation induced Auger electron Spectroscopy (PAES) and CDB measurements giving it unparalleled sensitivity to chemical structure at external surfaces, interfaces and internal pore surfaces. The system has a 3m flight path up to a micro channel plate (MCP) for the Auger electrons emitted from the sample. This gives a superior energy resolution for PAES. A solid rare gas(Neon) moderator was used for the generation of the monoenergetic positron beam. The positrons were successfully transported to the sample chamber using axial magnetic field generated with a series of Helmholtz coils. We will discuss the PAES and coincidence Doppler broadening measurements on graphene -Cu sample and present an analysis of the gamma spectra which indicates that a fraction of the positrons implanted at energies 7-60eV can become trapped at the graphene/metal interface. This work was supported by NSF Grant No. DMR 1508719 and DMR 1338130.

A slow positron beam generator for lifetime studies

NASA Technical Reports Server (NTRS)

Singh, Jag J.; Eftekhari, Abe; St.clair, Terry L.

1989-01-01

A slow positron beam generator using well-annealed polycrystalline tungsten moderators and a Na-22 positron source was developed. A 250 micro c source, deposited on a 2.54 micron thick aluminized mylar, is sandwiched between two (2.54 cm x 2.54 cm x 0.0127 cm) tungsten pieces. Two (2.54 cm x 2.54 cm x t cm) test polymer films insulate the two tungsten moderator pieces from the aluminized mylar source holder (t=0.00127 to 0.0127). A potential difference of 10 to 100 volts--depending on the test polymer film thickness (t)--is applied between the tungsten pieces and the source foil. Thermalized positrons diffusing out of the moderator pieces are attracted to the source foil held at an appropriate potential below the moderator pieces. These positrons have to pass through the test polymer films before they can reach the source foil. The potential difference between the moderator pieces and the aluminized mylar is so adjusted as to force the positrons to stop in the test polymer films. Thus the new generator becomes an effective source of positrons for assaying thin polymer films for their molecular morphology.

The intense slow positron beam facility at the PULSTAR reactor and applications in nano-materials study

NASA Astrophysics Data System (ADS)

Liu, Ming; Moxom, Jeremy; Hawari, Ayman I.; Gidley, David W.

2013-04-01

An intense slow positron beam has been established at the PULSTAR nuclear research reactor of North Carolina State University. The slow positrons are generated by pair production in a tungsten moderator from gammarays produced in the reactor core and by neutron capture reactions in cadmium. The moderated positrons are electrostatically extracted and magnetically guided out of the region near the core. Subsequently, the positrons are used in two spectrometers that are capable of performing positron annihilation lifetime spectroscopy (PALS) and positron Doppler broadening spectroscopy (DBS) to probe the defect and free volume properties of materials. One of the spectrometers (e+-PALS) utilizes an rf buncher to produce a pulsed beam and has a timing resolution of 277 ps. The second spectrometer (Ps-PALS) uses a secondary electron timing technique and is dedicated to positronium lifetime measurements with an approximately 1 ns timing resolution. PALS measurements have been conducted in the e+-PALS spectrometer on a series of nano-materials including organic photovoltaic thin films, membranes for filtration, and polymeric fibers. These studies have resulted in understanding some critical issues related to the development of the examined nano-materials.

Recent Developments in Positron Emission Tomography (PET) Instrumentation

DOE R&D Accomplishments Database

Derenzo, S. E.; Budinger, T. F.

1986-04-01

This paper presents recent detector developments and perspectives for positron emission tomography (PET) instrumentation used for medical research, as well as the physical processes in positron annihilation, photon scattering and detection, tomograph design considerations, and the potentials for new advances in detectors.

Positron production using a 1.7 MV pelletron accelerator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alcantara, K. F.; Santos, A. C. F.; Crivelli, P.

2013-04-19

We report the foremost phase of a fourth generation positron source, being constructed at the Federal University of Rio de Janeiro. Positron yields are reported by making use of the {sup 19}F(p,{alpha}e{sup +}e{sup -}){sup 16}O reaction, where the fluorine target is in the form of a CaF{sub 2} pellet. Positron production has been observed by detecting 511 keV annihilation gamma rays emerging from the irradiated CaF{sub 2} target.

Positrons in the Galaxy: Their Births, Marriages and Deaths

NASA Technical Reports Server (NTRS)

Skinner, Gerald K.

2010-01-01

High energy (approximately GeV) positrons are seen within cosmic rays and observation of a narrow line at 511 keV shows that positrons are annihilating in the galaxy after slowing down to approximately keV energies or less. Our state of knowledge of the origin of these positrons, of the formation of positronium 'atoms', and of the circumstances of their annihilation or escape from the galaxy are reviewed and the question of whether the two phenomena are linked is discussed.

Analytical electron microscopic studies and positron lifetime measurements in Al-doped MgO crystals

NASA Astrophysics Data System (ADS)

Pedrosa, M. A.; Pareja, R.; González, R.; Abraham, M. M.

1987-07-01

MgO crystals intentionally doped with Al were characterized by analytical electron microscopic examinations and positron lifetime measurements. Large spinel (MgO Al2O3) precipitates were observed in samples with high contents of Al. A well-defined crystallographic relationship between the precipitates and the matrix was found. The characteristics of positron lifetime spectra appear to depend on the valence state of the different impurities in the MgO lattice suggesting that positrons are trapped by vacancy impurity complexes.

Positron Annihilation in Polycrystalline Silver Samples Subjected to the Stretching Force

NASA Astrophysics Data System (ADS)

Pajak, J.; Rudzińska, W.; Pietrzak, R.; Szymański, Cz.; Smiatek, W.

Angular distributions of the positron annihilation quanta, positron lifetime and resistivity were measured for polycrystalline silver samples deformed by uniaxial tension up to different deformation degrees. The S parameter as a function of deformation degree of the sample has been determined. The data obtained for silver samples elongated up to different elongation degrees indicate the dominant role of vacancies and larger defects type clusters created during the deformation process. The positron annihilation data are corrob-orated by results obtained by resistivity measurements.

Portable modular detection system

DOEpatents

Brennan, James S [Rodeo, CA; Singh, Anup [Danville, CA; Throckmorton, Daniel J [Tracy, CA; Stamps, James F [Livermore, CA

2009-10-13

Disclosed herein are portable and modular detection devices and systems for detecting electromagnetic radiation, such as fluorescence, from an analyte which comprises at least one optical element removably attached to at least one alignment rail. Also disclosed are modular detection devices and systems having an integrated lock-in amplifier and spatial filter and assay methods using the portable and modular detection devices.

Modularity-like objective function in annotated networks

NASA Astrophysics Data System (ADS)

Xie, Jia-Rong; Wang, Bing-Hong

2017-12-01

We ascertain the modularity-like objective function whose optimization is equivalent to the maximum likelihood in annotated networks. We demonstrate that the modularity-like objective function is a linear combination of modularity and conditional entropy. In contrast with statistical inference methods, in our method, the influence of the metadata is adjustable; when its influence is strong enough, the metadata can be recovered. Conversely, when it is weak, the detection may correspond to another partition. Between the two, there is a transition. This paper provides a concept for expanding the scope of modularity methods.

Modular organization and hospital performance.

PubMed

Kuntz, Ludwig; Vera, Antonio

2007-02-01

The concept of modularization represents a modern form of organization, which contains the vertical disaggregation of the firm and the use of market mechanisms within hierarchies. The objective of this paper is to examine whether the use of modular structures has a positive effect on hospital performance. The empirical section makes use of multiple regression analyses and leads to the main result that modularization does not have a positive effect on hospital performance. However, the analysis also finds out positive efficiency effects of two central ideas of modularization, namely process orientation and internal market mechanisms.

Modular analysis of biological networks.

PubMed

Kaltenbach, Hans-Michael; Stelling, Jörg

2012-01-01

The analysis of complex biological networks has traditionally relied on decomposition into smaller, semi-autonomous units such as individual signaling pathways. With the increased scope of systems biology (models), rational approaches to modularization have become an important topic. With increasing acceptance of de facto modularity in biology, widely different definitions of what constitutes a module have sparked controversies. Here, we therefore review prominent classes of modular approaches based on formal network representations. Despite some promising research directions, several important theoretical challenges remain open on the way to formal, function-centered modular decompositions for dynamic biological networks.

Full characterization of modular values for finite-dimensional systems

NASA Astrophysics Data System (ADS)

Ho, Le Bin; Imoto, Nobuyuki

2016-06-01

Kedem and Vaidman obtained a relationship between the spin-operator modular value and its weak value for specific coupling strengths [14]. Here we give a general expression for the modular value in the n-dimensional Hilbert space using the weak values up to (n - 1)th order of an arbitrary observable for any coupling strength, assuming non-degenerated eigenvalues. For two-dimensional case, it shows a linear relationship between the weak value and the modular value. We also relate the modular value of the sum of observables to the weak value of their product.

Studies Of Oxidation And Thermal Reduction Of The Cu(100) Surface Using Positron Annihilation Induced Auger Electron Spectroscopy

NASA Astrophysics Data System (ADS)

Fazleev, N. G.; Nadesalingam, M. P.; Maddox, W.; Weiss, A. H.

2011-06-01

Positron annihilation induced Auger electron spectroscopy (PAES) measurements from the surface of an oxidized Cu(100) single crystal show a large increase in the intensity of the annihilation induced Cu M2,3VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300 °C. The PAES intensity then decreases monotonically as the annealing temperature is increased to ˜550 °C. Experimental positron annihilation probabilities with Cu 3p and O 1s core electrons are estimated from the measured intensities of the positron annihilation induced Cu M2,3VV and O KLL Auger transitions. PAES results are analyzed by performing calculations of positron surface states and annihilation probabilities of the surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface and various surface structures associated with low and high oxygen coverages. The variations in atomic structure and chemical composition of the topmost layers of the oxidized Cu(100) surface are found to affect localization and spatial extent of the positron surface state wave function. The computed positron binding energy and annihilation characteristics reveal their sensitivity to charge transfer effects, atomic structure and chemical composition of the topmost layers of the oxidized Cu(100) surface. Theoretical positron annihilation probabilities with Cu 3p and O 1s core electrons computed for the oxidized Cu(100) surface are compared with experimental ones. The obtained results provide a demonstration of thermal reduction of the copper oxide surface after annealing at 300 °C followed by re-oxidation of the Cu(100) surface at higher annealing temperatures presumably due to diffusion of subsurface oxygen to the surface.

Studies Of Oxidation And Thermal Reduction Of The Cu(100) Surface Using Positron Annihilation Induced Auger Electron Spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fazleev, N. G.; Department of Physics, Kazan State University, Kazan 420008; Nadesalingam, M. P.

2011-06-01

Positron annihilation induced Auger electron spectroscopy (PAES) measurements from the surface of an oxidized Cu(100) single crystal show a large increase in the intensity of the annihilation induced Cu M2,3VV Auger peak as the sample is subjected to a series of isochronal anneals in vacuum up to annealing temperature 300 deg. C. The PAES intensity then decreases monotonically as the annealing temperature is increased to {approx}550 deg. C. Experimental positron annihilation probabilities with Cu 3p and O 1s core electrons are estimated from the measured intensities of the positron annihilation induced Cu M{sub 2,3}VV and O KLL Auger transitions. PAESmore » results are analyzed by performing calculations of positron surface states and annihilation probabilities of the surface-trapped positrons with relevant core electrons taking into account the charge redistribution at the surface and various surface structures associated with low and high oxygen coverages. The variations in atomic structure and chemical composition of the topmost layers of the oxidized Cu(100) surface are found to affect localization and spatial extent of the positron surface state wave function. The computed positron binding energy and annihilation characteristics reveal their sensitivity to charge transfer effects, atomic structure and chemical composition of the topmost layers of the oxidized Cu(100) surface. Theoretical positron annihilation probabilities with Cu 3p and O 1s core electrons computed for the oxidized Cu(100) surface are compared with experimental ones. The obtained results provide a demonstration of thermal reduction of the copper oxide surface after annealing at 300 deg. C followed by re-oxidation of the Cu(100) surface at higher annealing temperatures presumably due to diffusion of subsurface oxygen to the surface.« less

Development and Testing of the Positron Identification By Coincident Annihilation Photons (PICAP) System

NASA Astrophysics Data System (ADS)

Tran, D.; Connell, J. J.; Lopate, C.; Bickford, B.

2014-12-01

Moderate energy positrons (~few to 10 MeV) have seldom been observed in the Heliosphere, due primarily to there not having been dedicated instruments for such measurements. Their detection would have implications in the study of Solar energetic particle events and the transport and modulation of the Solar wind and Galactic cosmic rays. The Positron Identification by Coincident Annihilation Photons (PICAP) system is designed specifically to measure these moderate energy positrons by simultaneously detecting the two 511-keV γ-ray photons that result from a positron stopping in the instrument and the subsequent electron-positron annihilation. This method is also expected to effectively discriminate positrons from protons by measuring the amount of energy deposited in the detectors (dE/dx versus residual energy). PICAP offers a low-mass, low-power option for measuring positrons, electrons, and ions in space. Following Monte Carlo modeling, a PICAP laboratory prototype, adaptable to a space-flight design, was designed, built, and tested. This instrument is comprised of (Si) solid-state detectors, plastic scintillation detectors, and high-Z BGO crystal scintillator suitable for detecting the 511-keV γ rays. The prototype underwent preliminary laboratory testing and calibration using radioactive sources for the purpose of establishing functionality. It has since been exposed to beams of energetic protons (up to ~200 MeV) at Massachusetts General Hospital's Francis H. Burr Proton Beam Therapy Center and positrons and electrons (up to ~10 MeV) at Idaho State University's Idaho Accelerator Center. The goal is to validate modeling and determine the performance of the instrument concept. We will present a summary of modeling calculations and analysis of data taken at the accelerator tests. This work is 95% supported by NASA Grant NNX10AC10G.