Science.gov

Sample records for molecular research division

  1. Materials and Molecular Research Division annual report 1980

    SciTech Connect

    Not Available

    1981-06-01

    Progress made in the following research areas is reported: materials sciences (metallurgy and ceramics, solid state physics, materials chemistry); chemical sciences (fundamental interactions, processes and techniques); nuclear sciences; fossil energy; advanced isotope separation technology; energy storage; magnetic fusion energy; and nuclear waste management.

  2. Environmental Research Division: fundamental molecular physics and chemistry. Annual report, January-December 1983. Part I

    SciTech Connect

    Not Available

    1985-03-01

    Research progress is reported in the following areas: (1) photoionization of radicals or excited states; (2) molecular spectroscopy by resonant multiphoton ionization; (3) studies conducted with the synchrotron radiation facility at the National Bureau of Standards; (4) theoretical studies on molecular photoabsorption; (5) analysis of photoabsorption spectra of open-shell atoms; (6) the electron energy-loss spectra of molecules; and (7) cross sections and stopping powers. Items have been individually abstracted for the data base. (ACR)

  3. Radiological and Environmental Research Division annual report, October 1979-September 1980: fundamental molecular physics and chemistry

    SciTech Connect

    Inokuti, Mitio; Dehmer, P. M.; Pratt, S. T.; Poliakoff, E. D.; Dehmer, J. L.; Stockbauer, Roger; Dill, Dan; Parr, A. C.; Jackson, K. H.; Zare, R. N.; Person, J. C.; Nicole, P. P.; Fowler, D. E.; Codling, K.; West, J. B.; Ederer, D. L.; Cole, B. E.; Loomba, D.; Wallace, Scott; Swanson, J. R.; Poliakoff, E. D.; Spence, David; Chupka, W. A.; Stevens, C. M.; Shyn, W. T.; Sharp, W. E.; Kim, Y. K.; Eggarter, E.; Baer, T.; Hanson, J. D.; Shimamura, Isao; Dillon, Michael A.

    1981-09-01

    Research is reported on the physics and chemistry of atoms, ions, and molecules, especially their interactions with external agents such as photons and electrons. Individual items from the report were prepared separately for the data base. (GHT)

  4. 2008 Research Portfolio: Research & Development Division

    ERIC Educational Resources Information Center

    Educational Testing Service, 2008

    2008-01-01

    This document describes the breadth of the research being conducted in 2008 by the Research and Development Division at Educational Testing Service (ETS). The research described falls into three large categories: (1) Research supported by the ETS research allocation; (2) Research funded by testing programs at ETS; and (3) Research funded by…

  5. Electronics Division research and development

    NASA Astrophysics Data System (ADS)

    MacRoberts, M. D. J.; Courtney, E. J.

    1984-03-01

    The status of the research development activities in the Electronics Division at the Los Alamos National Laboratory is described. Much of the work described is sponsored by the Laboratory; however, other topics are included for completeness. The Fuels Cells for Transportation Applications and the majority of the electrochemistry research are reported separately in LA-9787-PR. The Thermionic Integrated Circuits are being reported separately. The following topics are continuations of articles reported in Electronics Division Research and Development, October 1, 1981-September 30, 1982 (LA-9726-PR): Photoconductive Circuit Elements, Photoconductive Materials for Far-Infrared Detector Applications, Saturable Ferromagnetic Elements, Repetitive Opening Switches, Capacitor Test Facility, Fast Gating of Microchannel-Plate Image Intensifiers, and Oxygen-Reduction Reaction - Electrode Kinetics and Electrocatalysis. The following topics are new work or were included for completeness: Photoconductive Power Switches, Ion Beam Analysis, Link Access Control and Encryption System, Coded Aperture Imaging of Gamma-Ray Sources, and Multilayer Printed Wiring Boards.

  6. Molecular mechanisms of asymmetric division in oocytes.

    PubMed

    Sun, Shao-Chen; Kim, Nam-Hyung

    2013-08-01

    In contrast to symmetric division in mitosis, mammalian oocyte maturation is characterized by asymmetric cell division that produces a large egg and a small polar body. The asymmetry results from oocyte polarization, which includes spindle positioning, migration, and cortical reorganization, and this process is critical for fertilization and the retention of maternal components for early embryo development. Although actin dynamics are involved in this process, the molecular mechanism underlying this remained unclear until the use of confocal microscopy and live cell imaging became widespread in recent years. Information obtained through a PubMed database search of all articles published in English between 2000 and 2012 that included the phrases "oocyte, actin, spindle migration," "oocyte, actin, polar body," or "oocyte, actin, asymmetric division" was reviewed. The actin nucleation factor actin-related protein 2/3 complex and its nucleation-promoting factors, formins and Spire, and regulators such as small GTPases, partitioning-defective/protein kinase C, Fyn, microRNAs, cis-Golgi apparatus components, myosin/myosin light-chain kinase, spindle stability regulators, and spindle assembly checkpoint regulators, play critical roles in asymmetric cell division in oocytes. This review summarizes recent findings on these actin-related regulators in mammalian oocyte asymmetric division and outlines a complete signaling pathway.

  7. Fundamental molecular physics and chemistry. Radiological and Environmental Research Division annual report, October 1981-December 1982. Pt. 1

    SciTech Connect

    Not Available

    1983-12-01

    This document is the twelfth Annual Report of our Fundamental Molecular Physics and Chemistry Program. Scientifically, the work of the program deals with aspects of the physics and chemistry of molecules related to their interactions with photons, electrons, and other external agents. We chose these areas of study in view of our matic goals; that is to say, we chose them so that the eventual outcome of our work meets some of the needs of the US Department of Energy (DOE) and of other government agencies that support our research. First, we endeavor to determine theoretically and experimentally cross sections for electron and photon interactions with molecules, because those cross sections are indispensable for detailed microscopic analyses of the earliest processes of radiation action on any molecular substance, including biological materials. Those analyses in turn provide a sound basis for radiology and radiation dosimetry. Second, we study the spectroscopy of certain molecules and of small clusters of molecules because this topic is fundamental to the full understanding of atmospheric-pollutant chemistry.

  8. Ecological Research Division, Marine Research Program

    SciTech Connect

    Not Available

    1980-05-01

    This report presents program summaries of the various projects sponsored during 1979 by the Marine Research Program of the Ecological Research Division. Program areas include the effects of petroleum hydrocarbons on the marine environment; a study of the baseline ecology of a proposed OTEC site near Puerto Rico; the environmental impact of offshore geothermal energy development; the movement of radionuclides through the marine environment; the environmental aspects of power plant cooling systems; and studies of the physical and biological oceangraphy of the continental shelves bordering the United States.

  9. Environmental Research Division technical progress report: January 1986--October 1987

    SciTech Connect

    Not Available

    1988-07-01

    Technical process in the various research activities of Argonne National Laboratory's Environmental Research Division is reported for the period 1986-1987. Textual, graphic, and tabular information is used to briefly summarize (in separate chapters) the work of the Division's Atmospheric Physics, Environmental Effects Research, Fundamental Molecular Physics and Chemistry, and Organic Geochemistry and Environmental Instrumentation Programs. Information on professional qualifications, awards, and outstanding professional activities of staff members, as well as lists of publications, oral presentations, special events organized, and participants in educational programs, are provided in appendices at the end of each chapter. Individual projects under each division are processed separately for the data bases.

  10. Research Networks Map | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention supports major scientific collaborations and research networks at more than 100 sites across the United States. Seven Major Programs' sites are shown on this map. | The Division of Cancer Prevention supports major scientific collaborations and research networks at more than 100 sites across the United States.

  11. Acoustics Division recent accomplishments and research plans

    NASA Technical Reports Server (NTRS)

    Clark, L. R.; Morgan, H. G.

    1986-01-01

    The research program currently being implemented by the Acoustics Division of NASA Langley Research Center is described. The scope, focus, and thrusts of the research are discussed and illustrated for each technical area by examples of recent technical accomplishments. Included is a list of publications for the last two calendar years. The organization, staff, and facilities are also briefly described.

  12. Environmental Research Division technical progress report, January 1984-December 1985

    SciTech Connect

    Not Available

    1986-05-01

    Technical progress in the various research and assessment activities of Argonne National Laboratory's Environmental Research Division is reported for the period 1984 to 1985. Textual, graphic, and tabular information is used to briefly summarize (in separate chapters) the work of the Division's Atmospheric Physics, Environmental Effects Research, Environmental Impacts, Fundamental Molecular Physics and Chemistry, and Waste Management Programs. Information on professional qualifications, awards, and outstanding professional activities of staff members, as well as lists of publications, oral presentations, special events organized, and participants in educational programs, are provided in appendices at the end of each chapter.

  13. Energy Technology Division research summary - 1999.

    SciTech Connect

    1999-03-31

    The Energy Technology Division provides materials and engineering technology support to a wide range of programs important to the US Department of Energy. As shown on the preceding page, the Division is organized into ten sections, five with concentrations in the materials area and five in engineering technology. Materials expertise includes fabrication, mechanical properties, corrosion, friction and lubrication, and irradiation effects. Our major engineering strengths are in heat and mass flow, sensors and instrumentation, nondestructive testing, transportation, and electromechanics and superconductivity applications. The Division Safety Coordinator, Environmental Compliance Officers, Quality Assurance Representative, Financial Administrator, and Communication Coordinator report directly to the Division Director. The Division Director is personally responsible for cultural diversity and is a member of the Laboratory-wide Cultural Diversity Advisory Committee. The Division's capabilities are generally applied to issues associated with energy production, transportation, utilization, or conservation, or with environmental issues linked to energy. As shown in the organization chart on the next page, the Division reports administratively to the Associate Laboratory Director (ALD) for Energy and Environmental Science and Technology (EEST) through the General Manager for Environmental and Industrial Technologies. While most of our programs are under the purview of the EEST ALD, we also have had programs funded under every one of the ALDs. Some of our research in superconductivity is funded through the Physical Research Program ALD. We also continue to work on a number of nuclear-energy-related programs under the ALD for Engineering Research. Detailed descriptions of our programs on a section-by-section basis are provided in the remainder of this book.

  14. Energy Technology Division research summary -- 1994

    SciTech Connect

    Not Available

    1994-09-01

    Research funded primarily by the NRC is directed toward assessing the roles of cyclic fatigue, intergranular stress corrosion cracking, and irradiation-assisted stress corrosion cracking on failures in light water reactor (LWR) piping systems, pressure vessels, and various core components. In support of the fast reactor program, the Division has responsibility for fuel-performance modeling and irradiation testing. The Division has major responsibilities in several design areas of the proposed International Thermonuclear Experimental Reactor (ITER). The Division supports the DOE in ensuring safe shipment of nuclear materials by providing extensive review of the Safety Analysis Reports for Packaging (SARPs). Finally, in the nuclear area they are investigating the safe disposal of spent fuel and waste. In work funded by DOE`s Energy Efficiency and Renewable Energy, the high-temperature superconductivity program continues to be a major focal point for industrial interactions. Coatings and lubricants developed in the division`s Tribology Section are intended for use in transportation systems of the future. Continuous fiber ceramic composites are being developed for high-performance heat engines. Nondestructive testing techniques are being developed to evaluate fiber distribution and to detect flaws. A wide variety of coatings for corrosion protection of metal alloys are being studied. These can increase lifetimes significant in a wide variety of coal combustion and gasification environments.

  15. Energy Technology Division research summary 1997.

    SciTech Connect

    1997-10-21

    The Energy Technology Division provides materials and engineering technology support to a wide range of programs important to the US Department of Energy. As shown on the preceding page, the Division is organized into ten sections, five with concentrations in the materials area and five in engineering technology. Materials expertise includes fabrication, mechanical properties, corrosion, friction and lubrication, and irradiation effects. Our major engineering strengths are in heat and mass flow, sensors and instrumentation, nondestructive testing, transportation, and electromechanics and superconductivity applications. The Division Safety Coordinator, Environmental Compliance Officers, Quality Assurance Representative, Financial Administrator, and Communication Coordinator report directly to the Division Director. The Division Director is personally responsible for cultural diversity and is a member of the Laboratory-wide Cultural Diversity Advisory Committee. The Division's capabilities are generally applied to issues associated with energy production, transportation, utilization or conservation, or with environmental issues linked to energy. As shown in the organization chart on the next page, the Division reports administratively to the Associate Laboratory Director (ALD) for Energy and Environmental Science and Technology (EEST) through the General Manager for Environmental and Industrial Technologies. While most of our programs are under the purview of the EEST ALD, we also have had programs funded under every one of the ALDs. Some of our research in superconductivity is funded through the Physical Research Program ALD. We also continue to work on a number of nuclear-energy-related programs under the ALD for Engineering Research. Detailed descriptions of our programs on a section-by-section basis are provided in the remainder of this book. This Overview highlights some major trends. Research related to the operational safety of commercial light water nuclear

  16. 2010-11 Research Portfolio: Research & Development Division

    ERIC Educational Resources Information Center

    Educational Testing Service, 2010

    2010-01-01

    This document describes the breadth of the research that the ETS (Educational Testing Service) Research & Development division is conducting in 2010. This portfolio will be updated in early 2011 to reflect changes to existing projects and new projects that were added after this document was completed. The research described in this portfolio falls…

  17. Engineering Research Division publication report, calendar year 1980

    SciTech Connect

    Miller, E.K.; Livingston, P.L.; Rae, D.C.

    1980-06-01

    Each year the Engineering Research Division of the Electronics Engineering Department at Lawrence Livermore Laboratory has issued an internal report listing all formal publications produced by the Division during the calendar year. Abstracts of 1980 reports are presented.

  18. 78 FR 28630 - Pfizer Therapeutic Research, Pfizer Worldwide Research & Development Division, Formerly Known as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ... Employment and Training Administration Pfizer Therapeutic Research, Pfizer Worldwide Research & Development... Therapeutic Research, Pfizer Worldwide Research & Development Division, Comparative Medicine Department... Research, Pfizer Worldwide Research & Development Division, formerly known as Warner Lambert Company...

  19. Molecular Code Division Multiple Access: Gaussian Mixture Modeling

    NASA Astrophysics Data System (ADS)

    Zamiri-Jafarian, Yeganeh

    Communications between nano-devices is an emerging research field in nanotechnology. Molecular Communication (MC), which is a bio-inspired paradigm, is a promising technique for communication in nano-network. In MC, molecules are administered to exchange information among nano-devices. Due to the nature of molecular signals, traditional communication methods can't be directly applied to the MC framework. The objective of this thesis is to present novel diffusion-based MC methods when multi nano-devices communicate with each other in the same environment. A new channel model and detection technique, along with a molecular-based access method, are proposed in here for communication between asynchronous users. In this work, the received molecular signal is modeled as a Gaussian mixture distribution when the MC system undergoes Brownian noise and inter-symbol interference (ISI). This novel approach demonstrates a suitable modeling for diffusion-based MC system. Using the proposed Gaussian mixture model, a simple receiver is designed by minimizing the error probability. To determine an optimum detection threshold, an iterative algorithm is derived which minimizes a linear approximation of the error probability function. Also, a memory-based receiver is proposed to improve the performance of the MC system by considering previously detected symbols in obtaining the threshold value. Numerical evaluations reveal that theoretical analysis of the bit error rate (BER) performance based on the Gaussian mixture model match simulation results very closely. Furthermore, in this thesis, molecular code division multiple access (MCDMA) is proposed to overcome the inter-user interference (IUI) caused by asynchronous users communicating in a shared propagation environment. Based on the selected molecular codes, a chip detection scheme with an adaptable threshold value is developed for the MCDMA system when the proposed Gaussian mixture model is considered. Results indicate that the

  20. A Division of Research in an Academic Clinical Department.

    ERIC Educational Resources Information Center

    Traystman, Richard J.

    1982-01-01

    Discusses in general the importance of a research division, whether basic or clinical, in an academic setting and factors to consider in establishing one. Uses John Hopkins' newly created research division for Anesthesiology and Critical Care Medicine to specifically address funding and intra- and interdepartmental clinical research programs. (DC)

  1. A Division of Research in an Academic Clinical Department.

    ERIC Educational Resources Information Center

    Traystman, Richard J.

    1982-01-01

    Discusses in general the importance of a research division, whether basic or clinical, in an academic setting and factors to consider in establishing one. Uses John Hopkins' newly created research division for Anesthesiology and Critical Care Medicine to specifically address funding and intra- and interdepartmental clinical research programs. (DC)

  2. High energy physics division semiannual report of research activities

    SciTech Connect

    Schoessow, P.; Moonier, P.; Talaga, R.; Wagner, R. )

    1991-08-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1, 1991--June 30, 1991. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  3. Division of Biological and Medical Research annual technical report 1982

    SciTech Connect

    Rosenthal, M.W.

    1983-05-01

    This report summarizes research during 1982 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Carcinogenesis address mechanisms of chemical and radiation carcinogenesis including the processes of tumor initiation and promotion. The studies employ rat liver and mouse skin models as well as human rodent cell culture systems. The use of liposomes for metal mobilization is also explored. Low Level Radiation studies include delineation of the hematopoietic and other responses of dogs to continuous low level gamma irradiation, comparison of lifetime effects in mice of low level neutron and gamma irradiation, and study of the genetic effects of high LET radiation. Molecular Biology research develops two-dimensional electrophoresis systems for diagnosis and detection of cancer and other diseases. Fundamental structural and biophysical investigations of immunoglobulins and other key proteins are included, as are studies of cell growth, and of molecular and cellular effects of solar uv light. Research in Toxicology uses cellular, physiological, whole animal, and chronobiological end points and chemical separations to elucidate mechanisms and evaluate hazards of coal conversion by-products, actinides, and toxic metals. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  4. Molecular Research in Aquaculture

    USDA-ARS?s Scientific Manuscript database

    Molecular research and biotechnology have long been fields of study with applications useful to aquaculture and other animal sciences. Molecular Research in Aquaculture looks to provide an understanding of molecular research and its applications to the aquaculture industry in a format that allows in...

  5. CPFP Summer Curriculum: Molecular Prevention Course | Division of Cancer Prevention

    Cancer.gov

    This Cancer Prevention Fellowship Program (CPFP) one-week course on molecular aspects of cancer prevention follows the Principles and Practice of Cancer Prevention and Control course. It provides a strong background about molecular biology and genetics of cancer, and an overview of cutting-edge research and techniques in the fields of molecular epidemiology, biomarkers, multi-omic, and translational research. The following topics will be typically presented: |

  6. Biomedical Research Division significant accomplishments for FY 1983

    NASA Technical Reports Server (NTRS)

    Martello, N. V.

    1984-01-01

    Various research and technology activities of Ames Research Center's Biomedical Research Division are described. Contributions to the Space Administration's goals in the life sciences include research in operational medicine, cardiovascular deconditioning, motion sickness, bone alterations, muscle atrophy, fluid and electrolyte changes, radiation effects and protection, human behavior and performance, general biomedical research, and gravitational biology.

  7. Division of Biological and Medical Research annual technical report, 1981

    SciTech Connect

    Rosenthal, M.W.

    1982-06-01

    This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

  8. The Space Electronics Division: Research for Today and Tomorrow

    NASA Technical Reports Server (NTRS)

    1991-01-01

    This video gives an overview of work being done by the different branches of the Space Electronics Division at LeRC. The video highlights electron beam, solid state, high speed circuit design, and high frequency communication research.

  9. Engineering Research Division report on reports: calendar year 1979. [LLL

    SciTech Connect

    Gardner, C.L.; Johnston, S.J.

    1980-03-01

    A bibliography of publications of members of the Engineering Research Division of the Electronics Engineering Department is presented for 1979. Abstracts for 148 publications are included, along with author and keywork indexes. (RWR)

  10. Molecular basis of peroxisome division and proliferation in plants.

    PubMed

    Hu, Jianping

    2010-01-01

    Peroxisomes are multifunctional organelles whose abundance varies depending on the cell type, organism, developmental stage, and environmental and metabolic conditions in which the organism lives. Plant peroxisomes are essential to embryo viability and are involved in numerous biochemical processes in development and in plant interaction with the environment. In the past few years, several classes of peroxisomal proteins required for various steps in peroxisome division and proliferation and a signaling pathway underlying the light induction of peroxisome proliferation have been identified from the model plant species Arabidopsis thaliana. Some of the major components of the peroxisome division apparatus have been conserved from plants to yeasts and animals, whereas plant-specific components are also being revealed. Environmental factors and nuclear events that control the process appear to be highly unique in different evolutionary lineages. Future research needs to identify additional members of the peroxisome division/proliferation pathways and to dissect signaling pathways by which various environmental and metabolic cues regulate the abundance of peroxisomes in plants. Copyright 2010 Elsevier Inc. All rights reserved.

  11. Accelerator and Fusion Research Division 1989 summary of activities

    SciTech Connect

    Not Available

    1990-06-01

    This report discusses the research being conducted at Lawrence Berkeley Laboratory's Accelerator and Fusion Research Division. The main topics covered are: heavy-ion fusion accelerator research; magnetic fusion energy; advanced light source; center for x-ray optics; exploratory studies; high-energy physics technology; and bevalac operations.

  12. Division of Computer Research Summary of Awards. Fiscal Year 1984.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC. Directorate for Mathematical and Physical Sciences.

    Provided in this report are summaries of grants awarded by the National Science Foundation Division of Computer Research in fiscal year 1984. Similar areas of research are grouped (for the purposes of this report only) into these major categories: (1) computational mathematics; (2) computer systems design; (3) intelligent systems; (4) software…

  13. RESEARCH ACTIVITIES AT THE US EPA'S GULF ECOLOGY DIVISION

    EPA Science Inventory

    The purpose of this talk was to present an overview of research activities at the US EPA's Office of Research and Development, Gulf Ecology Division located on Pensacola Beach, Florida. The talk was organized into three major sections. The first section covered my educational b...

  14. RESEARCH ACTIVITIES AT THE US EPA'S GULF ECOLOGY DIVISION

    EPA Science Inventory

    The purpose of this talk was to present an overview of research activities at the US EPA's Office of Research and Development, Gulf Ecology Division located on Pensacola Beach, Florida. The talk was organized into three major sections. The first section covered my educational b...

  15. Division of Biological and Medical Research annual research summary, 1983

    SciTech Connect

    Barr, S.H.

    1984-08-01

    This research summary contains brief descriptions of research in the following areas: (1) mechanisms of hepatocarcinogenesis; (2) role of metals in cocarcinogenesis and the use of liposomes for metal mobilization; (3) control of mutagenesis and cell differentiation in cultured cells by tumor promoters; (4) radiation effects in mammalian cells; (5) radiation carcinogenesis and radioprotectors; (6) life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations; (7) mammalian genetics and biostatistics; (8) radiation toxicity studies; (9) hematopoiesis in chronic toxicity; (10) molecular biology studies; (11) chemical toxicology; (12) carcinogen identification and metabolism; (13) metal metabolism and toxicity; and (14) neurobehavioral chronobiology. (ACR)

  16. Research and technology activities at Ames Research Center's Biomedical Research Division

    NASA Technical Reports Server (NTRS)

    Martello, N.

    1985-01-01

    Various research and technology activities at Ames Research Center's Biomedical Research Division are described. Contributions to the Space Administration's goals in the life sciences include descriptions of research in operational medicine, cardiovascular deconditioning, motion sickness, bone alterations, muscle atrophy, fluid and electrolyte changes, radiation effects and protection, behavior and performance, gravitational biology, and life sciences flight experiments.

  17. Chemical Engineering Division research highlights, 1979

    SciTech Connect

    Burris, L.; Webster, D. S.; Barney, D. L.; Cafasso, F. A.; Steindler, M. J.

    1980-06-01

    In 1979, CEN conducted research and development in the following areas: (1) high-temperature, rechargeable lithium/iron sulfide batteries for electric vehicles and electric utility load leveling; (2) ambient-temperature batteries - improved lead-acid, nickel/zinc, and nickel/iron - for electric vehicles; (3) molten carbonate fuel cells for use by electric utilities; (4) coal technology - mainly fluidized-bed combustion of coal in the presence of SO/sub 2/ sorbent of limestone; (5) heat- and seed- recovery technology for open-cycle magnetohydrodynamic systems; (6) solar energy collectors and thermal energy storage; (7) fast breeder reactor chemistry research - chemical support of reactor safety studies, chemistry of irradiated fuels, and sodium technology; (8) fuel cycle technology - reprocessing of nuclear fuels, management of nuclear wastes, geologic migration studies, and proof-of-breeding studies for the Light Water Breeder Reactor; (9) magnetic fusion research - lithium processing technology and materials research; and (10) basic energy sciences - homogeneous catalysis, thermodynamics of inorganic and organic materials, environmental chemistry, electrochemistry, and physical properties of salt vapors. Separate abstracts were prepared for each of these areas.

  18. Division of Biological and Medical Research research summary 1984-1985

    SciTech Connect

    Barr, S.H.

    1985-08-01

    The Division of Biological and Medical Research at Argonne National Laboratory conducts multidisciplinary research aimed at defining the biological and medical hazards to man from energy technologies and new energy options. These technically oriented studies have a strong base in fundamental research in a variety of scientific disciplines, including molecular and cellular biology, biophysics, genetics, radiobiology, pharmacology, biochemistry, chemistry, environmental toxicology, and epidemiology. This research summary is organized into six parts. The first five parts reflect the Divisional structure and contain the scientific program chapters, which summarize the activities of the individual groups during the calendar year 1984 and the first half of 1985. To provide better continuity and perspective, previous work is sometimes briefly described. Although the summaries are short, efforts have been made to indicate the range of research activities for each group.

  19. Earth Sciences Division Research Summaries 2006-2007

    SciTech Connect

    DePaolo, Donald; DePaolo, Donald

    2008-07-21

    Research in earth and atmospheric sciences has become increasingly important in light of the energy, climate change, and other environmental issues facing the United States and the world. The development of new energy resources other than fossil hydrocarbons, the safe disposal of nuclear waste and greenhouse gases, and a detailed understanding of the climatic consequences of our energy choices are all critical to meeting energy needs while ensuring environmental safety. The cleanup of underground contamination and the preservation and management of water supplies continue to provide challenges, as they will for generations into the future. To address the critical energy and environmental issues requires continuing advances in our knowledge of Earth systems and our ability to translate that knowledge into new technologies. The fundamental Earth science research common to energy and environmental issues largely involves the physics, chemistry, and biology of fluids in and on the Earth. To manage Earth fluids requires the ability to understand their properties and behavior at the most fundamental molecular level, as well as prediction, characterization, imaging, and manipulation of those fluids and their behavior in real Earth reservoirs. The broad range of disciplinary expertise, the huge range of spatial and time scales, and the need to integrate theoretical, computational, laboratory and field research, represent both the challenge and the excitement of Earth science research. The Earth Sciences Division (ESD) of the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to addressing the key scientific and technical challenges that are needed to secure our energy future in an environmentally responsibly way. Our staff of over 200 scientists, UC Berkeley faculty, support staff and guests perform world-acclaimed fundamental research in hydrogeology and reservoir engineering, geophysics and geomechanics, geochemistry, microbial ecology

  20. Accelerator & Fusion Research Division: 1993 Summary of activities

    SciTech Connect

    Chew, J.

    1994-04-01

    The Accelerator and Fusion Research Division (AFRD) is not only one of the largest scientific divisions at LBL, but also the one of the most diverse. Major efforts include: (1) investigations in both inertial and magnetic fusion energy; (2) operation of the Advanced Light Source, a state-of-the-art synchrotron radiation facility; (3) exploratory investigations of novel radiation sources and colliders; (4) research and development in superconducting magnets for accelerators and other scientific and industrial applications; and (5) ion beam technology development for nuclear physics and for industrial and biomedical applications. Each of these topics is discussed in detail in this book.

  1. Environmental Sciences Division: Summaries of research in FY 1996

    SciTech Connect

    1997-06-01

    This document describes the Fiscal Year 1996 activities and products of the Environmental Sciences Division, Office of Biological and Environmental Research, Office of Energy Research. The report is organized into four main sections. The introduction identifies the basic program structure, describes the programs of the Environmental Sciences Division, and provides the level of effort for each program area. The research areas and project descriptions section gives program contact information, and provides descriptions of individual research projects including: three-year funding history, research objective and approach used in each project, and results to date. Appendixes provide postal and e-mail addresses for principal investigators and define acronyms used in the text. The indexes provide indexes of principal investigators, research institutions, and keywords for easy reference. Research projects are related to climatic change and remedial action.

  2. Health and Safety Research Division progress report for the period April 1, 1990--September 30, 1991

    SciTech Connect

    Kaye, S.V.

    1992-03-01

    This is a brief progress report from the Health and Safety Research Division of Oak Ridge National Laboratory. Information is presented in the following sections: Assessment Technology including Measurement Applications and Development, Pollutant Assessments, Measurement Systems Research, Dosimetry Applications Research, Metabolism and Dosimetry Research and Nuclear Medicine. Biological and Radiation Physics including Atomic, Molecular, and High Voltage Physics, Physics of Solids and Macromolecules, Liquid and Submicron Physics, Analytic Dosimetry and Surface Physics and Health Effects. Chemical Physics including Molecular Physics, Photophysics and Advanced Monitoring Development. Biomedical and Environmental Information Analysis including Human Genome and Toxicology, Chemical Hazard Evaluation and Communication, Environmental Regulations and Remediation and Information Management Technology. Risk Analysis including Hazardous Waste.

  3. AN OVERVIEW OF PATHOGEN RESEARCH IN THE MICROBIOLOGICAL AND CHEMICAL EXPOSURE ASSESSMENT RESEARCH DIVISION

    EPA Science Inventory

    The Microbiological and Chemical Exposure Assessment Research Division of the EPA Office of Research and Development's National Exposure Research Laboratory has a robust in-house research program aimed at developing better occurrence and exposure methods for waterborne pathogens....

  4. Broadening Participation in Research Focused, Upper-Division Learning Communities

    ERIC Educational Resources Information Center

    Hinckley, Robert A.; McGuire, John P.

    2015-01-01

    We address several challenges faced by those who wish to increase the number of faculty participating in upper-division learning communities that feature a student research experience. Using illustrations from our own learning community, we describe three strategies for success that focus on providing low cost incentives and other means to promote…

  5. NEAR ROADWAY RESEARCH IN THE ATMOSPHERIC MODELING DIVISION

    EPA Science Inventory

    This is a presentation to the CRC Mobile Source Air Toxics Workshop in Phoenix, AZ, on 23 October 2006. The presentation provides an overview of air quality modeling research in the USEPA/ORD/NERL's Atmospheric Modeling Division, with an emphasis on near-road pollutant character...

  6. Active Early Detection Research Network Grants | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  7. Accelerator and Fusion Research Division: Summary of activities, 1986

    SciTech Connect

    Not Available

    1987-04-15

    This report contains a summary of activities at the Lawrence Berkeley Laboratory's Accelerator and Fusion Research Division for the year 1986. Topics and facilities investigated in individual papers are: 1-2 GeV Synchrotron Radiation Source, the Center for X-Ray Optics, Accelerator Operations, High-Energy Physics Technology, Heavy-Ion Fusion Accelerator Research and Magnetic Fusion Energy. Six individual papers have been indexed separately. (LSP)

  8. Activities of the Structures Division, Lewis Research Center

    NASA Technical Reports Server (NTRS)

    1990-01-01

    The purpose of the NASA Lewis Research Center, Structures Division's 1990 Annual Report is to give a brief, but comprehensive, review of the technical accomplishments of the Division during the past calendar year. The report is organized topically to match the Center's Strategic Plan. Over the years, the Structures Division has developed the technology base necessary for improving the future of aeronautical and space propulsion systems. In the future, propulsion systems will need to be lighter, to operate at higher temperatures and to be more reliable in order to achieve higher performance. Achieving these goals is complex and challenging. Our approach has been to work cooperatively with both industry and universities to develop the technology necessary for state-of-the-art advancement in aeronautical and space propulsion systems. The Structures Division consists of four branches: Structural Mechanics, Fatigue and Fracture, Structural Dynamics, and Structural Integrity. This publication describes the work of the four branches by three topic areas of Research: (1) Basic Discipline; (2) Aeropropulsion; and (3) Space Propulsion. Each topic area is further divided into the following: (1) Materials; (2) Structural Mechanics; (3) Life Prediction; (4) Instruments, Controls, and Testing Techniques; and (5) Mechanisms. The publication covers 78 separate topics with a bibliography containing 159 citations. We hope you will find the publication interesting as well as useful.

  9. Materials and Components Technology Division research summary, 1992

    SciTech Connect

    Not Available

    1992-11-01

    The Materials and Components Technology Division (MCT) provides a research and development capability for the design, fabrication, and testing of high-reliability materials, components, and instrumentation. Current divisional programs related to nuclear energy support the development of the Integral Fast Reactor (IFR): life extension and accident analyses for light water reactors (LWRs); fuels development for research and test reactors; fusion reactor first-wall and blanket technology; and safe shipment of hazardous materials. MCT Conservation and Renewables programs include major efforts in high-temperature superconductivity, tribology, nondestructive evaluation (NDE), and thermal sciences. Fossil Energy Programs in MCT include materials development, NDE technology, and Instrumentation design. The division also has a complementary instrumentation effort in support of Arms Control Technology. Individual abstracts have been prepared for the database.

  10. Barrett's Esophagus Translational Research Network (BETRNet) | Division of Cancer Prevention

    Cancer.gov

    The goal of BETRNet is to reduce the incidence, morbidity, and mortality of esophageal adenocarcinoma by answering key questions related to the progression of the disease, especially in the premalignant stage. In partnership with NCI’s Division of Cancer Biology, multidisciplinary translational research centers collaborate to better understand the biology of Barrett's esophagus and esophageal adenocarcinoma to improve risk stratification and develop prevention strategies. | Multi-disciplinary, multi-institutional collaboration to enhance understanding of Barrett's esophagus and to prevent esophageal adenocarcinoma.

  11. Molecular and social regulation of worker division of labor in fire ants

    USDA-ARS?s Scientific Manuscript database

    Division of labor is a major achievement of social regulation in insect societies. Despite the greatinterest for this theme, the molecular basis for the regulation of division of labor has been investigated in detail only in honey bees, while nothing is known about the regulatory mechanisms operatin...

  12. Molecular and social regulation of worker division of labor in fire ants

    USDA-ARS?s Scientific Manuscript database

    Division of labor is a major achievement of social regulation in insect societies. Despite the great interest for this theme, the molecular basis for the regulation of division of labor has been investigated in detail only in honey bees, while nothing is known about the regulatory mechanisms operati...

  13. Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Cancer.gov

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health are offering a one week educational opportunity in "Nutrition and Cancer Prevention Research" for individuals with a sustained commitment to nutrition and health promotion. This one-week intense learning session provides specialized instruction in the role of diet and bioactive food components as modifiers of cancer incidence and tumor behavior. |

  14. Accelerator and Fusion Research Division: summary of activities, 1983

    SciTech Connect

    Not Available

    1984-08-01

    The activities described in this summary of the Accelerator and Fusion Research Division are diverse, yet united by a common theme: it is our purpose to explore technologically advanced techniques for the production, acceleration, or transport of high-energy beams. These beams may be the heavy ions of interest in nuclear science, medical research, and heavy-ion inertial-confinement fusion; they may be beams of deuterium and hydrogen atoms, used to heat and confine plasmas in magnetic fusion experiments; they may be ultrahigh-energy protons for the next high-energy hadron collider; or they may be high-brilliance, highly coherent, picosecond pulses of synchrotron radiation.

  15. About the Early Detection Research Group | Division of Cancer Prevention

    Cancer.gov

    The Early Detection Research Group supports research that seeks to determine the effectiveness, operating characteristics and clinical impact (harms as well as benefits) of cancer early detection technologies and practices, such as imaging and molecular biomarker approaches.   The group ran two large-scale early detection trials for which data and biospecimens are available for additional research: |

  16. Materials and Components Technology Division research summary, 1991

    SciTech Connect

    Not Available

    1991-04-01

    This division has the purpose of providing a R and D capability for design, fabrication, and testing of high-reliability materials, components, and instrumentation. Current divisional programs are in support of the Integral Fast Reactor, life extension for light water reactors, fuels development for the new production reactor and research and test reactors, fusion reactor first-wall and blanket technology, safe shipment of hazardous materials, fluid mechanics/materials/instrumentation for fossile energy systems, and energy conservation and renewables (including tribology, high- temperature superconductivity). Separate abstracts have been prepared for the data base.

  17. Molecular System for the Division of Self-Propelled Oil Droplets by Component Feeding.

    PubMed

    Banno, Taisuke; Toyota, Taro

    2015-06-30

    Unique dynamics using inanimate molecular assemblies have drawn a great amount of attention for demonstrating prebiomimetic molecular systems. For the construction of an organized logic combining two fundamental dynamics of life, we demonstrate here a molecular system that exhibits both division and self-propelled motion using oil droplets. The key molecule of this molecular system is a novel cationic surfactant containing a five-membered acetal moiety, and the molecular system can feed the self-propelled oil droplet composed of a benzaldehyde derivative and an alkanol. The division dynamics of the self-propelled oil droplets were observed through the hydrolysis of the cationic surfactant in bulk solution. The mechanism of the current dynamics is argued to be based on the supply of "fresh" oil components in the moving oil droplets, which is induced by the Marangoni instability. We consider this molecular system to be a prototype of self-reproducing inanimate molecular assembly exhibiting self-propelled motion.

  18. Energy and Environmental Systems Division 1981 research review

    SciTech Connect

    Not Available

    1982-04-01

    To effectively manage the nation's energy and natural resources, government and industry leaders need accurate information regarding the performance and economics of advanced energy systems and the costs and benefits of public-sector initiatives. The Energy and Environmental Systems Division (EES) of Argonne National Laboratory conducts applied research and development programs that provide such information through systems analysis, geophysical field research, and engineering studies. During 1981, the division: analyzed the production economics of specific energy resources, such as biomass and tight sands gas; developed and transferred to industry economically efficient techniques for addressing energy-related resource management and environmental protection problems, such as the reclamation of strip-mined land; determined the engineering performance and cost of advanced energy-supply and pollution-control systems; analyzed future markets for district heating systems and other emerging energy technologies; determined, in strategic planning studies, the availability of resources needed for new energy technologies, such as the imported metals used in advanced electric-vehicle batteries; evaluated the effectiveness of strategies for reducing scarce-fuel consumption in the transportation sector; identified the costs and benefits of measures designed to stabilize the financial condition of US electric utilities; estimated the costs of nuclear reactor shutdowns and evaluated geologic conditions at potential sites for permanent underground storage of nuclear waste; evaluated the cost-effectiveness of environmental regulations, particularly those affecting coal combustion; and identified the environmental effects of energy technologies and transportation systems.

  19. The molecular biology capstone assessment: a concept assessment for upper-division molecular biology students.

    PubMed

    Couch, Brian A; Wood, William B; Knight, Jennifer K

    2015-03-02

    Measuring students' conceptual understandings has become increasingly important to biology faculty members involved in evaluating and improving departmental programs. We developed the Molecular Biology Capstone Assessment (MBCA) to gauge comprehension of fundamental concepts in molecular and cell biology and the ability to apply these concepts in novel scenarios. Targeted at graduating students, the MBCA consists of 18 multiple-true/false (T/F) questions. Each question consists of a narrative stem followed by four T/F statements, which allows a more detailed assessment of student understanding than the traditional multiple-choice format. Questions were iteratively developed with extensive faculty and student feedback, including validation through faculty reviews and response validation through student interviews. The final assessment was taken online by 504 students in upper-division courses at seven institutions. Data from this administration indicate that the MBCA has acceptable levels of internal reliability (α=0.80) and test-retest stability (r=0.93). Students achieved a wide range of scores with a 67% overall average. Performance results suggest that students have an incomplete understanding of many molecular biology concepts and continue to hold incorrect conceptions previously documented among introductory-level students. By pinpointing areas of conceptual difficulty, the MBCA can provide faculty members with guidance for improving undergraduate biology programs.

  20. The Molecular Biology Capstone Assessment: A Concept Assessment for Upper-Division Molecular Biology Students

    PubMed Central

    Couch, Brian A.; Wood, William B.; Knight, Jennifer K.

    2015-01-01

    Measuring students’ conceptual understandings has become increasingly important to biology faculty members involved in evaluating and improving departmental programs. We developed the Molecular Biology Capstone Assessment (MBCA) to gauge comprehension of fundamental concepts in molecular and cell biology and the ability to apply these concepts in novel scenarios. Targeted at graduating students, the MBCA consists of 18 multiple-true/false (T/F) questions. Each question consists of a narrative stem followed by four T/F statements, which allows a more detailed assessment of student understanding than the traditional multiple-choice format. Questions were iteratively developed with extensive faculty and student feedback, including validation through faculty reviews and response validation through student interviews. The final assessment was taken online by 504 students in upper-division courses at seven institutions. Data from this administration indicate that the MBCA has acceptable levels of internal reliability (α = 0.80) and test–retest stability (r = 0.93). Students achieved a wide range of scores with a 67% overall average. Performance results suggest that students have an incomplete understanding of many molecular biology concepts and continue to hold incorrect conceptions previously documented among introductory-level students. By pinpointing areas of conceptual difficulty, the MBCA can provide faculty members with guidance for improving undergraduate biology programs. PMID:25713098

  1. Theory and Research Section. Education and Research Division. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on research in library science and the exhibition of library materials which were presented at the 1982 International Federation of Library Associations (IFLA) conference include: (1) "Terminological Problems of Networks," a discussion by Helena Kolarova Palkova of the meaning of "library networks" and…

  2. Earth Sciences Division Research Summaries 2002-2003

    SciTech Connect

    Bodvarsson, G.S.

    2003-11-01

    Research in earth and atmospheric sciences is becoming increasingly important in light of the energy, climate change, and environmental issues facing the United States and the world. The development of new energy resources other than hydrocarbons and the safe disposal of nuclear waste and greenhouse gases (such as carbon dioxide and methane) are critical to the future energy needs and environmental safety of this planet. In addition, the cleanup of many contaminated sites in the U.S., along with the preservation and management of our water supply, remain key challenges for us as well as future generations. Addressing these energy, climate change, and environmental issues requires the timely integration of earth sciences' disciplines (such as geology, hydrology, oceanography, climatology, geophysics, geochemistry, geomechanics, ecology, and environmental sciences). This integration will involve focusing on fundamental crosscutting concerns that are common to many of these issues. A primary focus will be the characterization, imaging, and manipulation of fluids in the earth. Such capabilities are critical to many DOE applications, from environmental restoration to energy extraction and optimization. The Earth Sciences Division (ESD) of the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab) is currently addressing many of the key technical issues described above. In this document, we present summaries of many of our current research projects. While it is not a complete accounting, it is representative of the nature and breadth of our research effort. We are proud of our scientific efforts, and we hope that you will find our research useful and exciting. Any comments on our research are appreciated and can be sent to me personally. This report is divided into five sections that correspond to the major research programs in the Earth Sciences Division: (1) Fundamental and Exploratory Research; (2) Nuclear Waste; (3) Energy Resources; (4) Environmental

  3. About the Nutritional Science Research Group | Division of Cancer Prevention

    Cancer.gov

    The Nutritional Science Research Group (NSRG) promotes and supports studies establishing a comprehensive understanding of the precise role of diet and food components in modulating cancer risk and tumor cell behavior. This focus includes approaches to characterize molecular targets and variability in individual responses to nutrients and dietary patterns. |

  4. Summary Report of the Atmospheric Modeling and Analysis Division's Research Activities for 2010

    EPA Science Inventory

    The research presented here was performed by the Atmospheric Modeling and Analysis Division (AMAD) of the National Exposure Research Laboratory in the U.S. Environmental Protection Agency’s (EPA’s) Office of Research and Development in Research Triangle Park, NC. The Division lea...

  5. Summary Report of the Atmospheric Modeling and Analysis Division's Research Activities for 2009

    EPA Science Inventory

    The research presented here was performed by the Atmospheric Modeling and Analysis Division (AMAD) under the National Exposure Research Laboratory in the U.S. Environmental Protection Agency’s (EPA’s) Office of Research and Development in Research Triangle Park, NC. The Division ...

  6. Summary Report of the Atmospheric Modeling and Analysis Division's Research Activities for 2010

    EPA Science Inventory

    The research presented here was performed by the Atmospheric Modeling and Analysis Division (AMAD) of the National Exposure Research Laboratory in the U.S. Environmental Protection Agency’s (EPA’s) Office of Research and Development in Research Triangle Park, NC. The Division lea...

  7. RESEARCH PROGRAMS AT THE ECOSYSTEMS RESEARCH DIVISION, U.S. ENVIRONMENTAL PROTECTION AGENCY

    EPA Science Inventory

    This presentation presents information on the research programs at the Ecosystems Research Division (ERD) of the U.S. Environmental Protection Agency located in Athens, Georgia. The presentation gives an overview of the Agency, laws and regulations that the Agency operates under,...

  8. RESEARCH PROGRAMS AT THE ECOSYSTEMS RESEARCH DIVISION, U.S. ENVIRONMENTAL PROTECTION AGENCY

    EPA Science Inventory

    This presentation presents information on the research programs at the Ecosystems Research Division (ERD) of the U.S. Environmental Protection Agency located in Athens, Georgia. The presentation gives an overview of the Agency, laws and regulations that the Agency operates under,...

  9. [Research on distribution and quality suitability division of Desmodium styracifolium].

    PubMed

    Li, Dan; Tang, Xiao-Min; Zhu, Shou-Dong; Yang, Quan; Cheng, Xuan-Xuan; Zhang, Chun-Rong; Pan, Li-Ming; Chen, Duan-Ni

    2017-02-01

    The research on distribution and quality suitability division of Desmodium styracifolium were formulated by Maxent and ArcGIS model based on the content of schaftoside and polysaccharide of D. styracifolium and its field research in the south and southwest areas of China (Guangdong, Guangxi, Hainan and Yunnan), and the most suitable habitats of distribution suitability and quality suitability were screened. The distribution suitability results indicated that average air temperature in April,mean temperature of coldest quarter, soil type, coldness index were found as the four dominant factors contributing to the plant distribution. The quality suitability results indicated that: ①Polysaccharide content and precipitation in April show significant positive correlation;Schaftoside content and mean temperature of April, mean temperature of coldest quarter show significant negative correlation. Schaftoside content shows significant negative correlation with the precipitation in October and November and the sunshine duration in April and May, while there is a significant positive correlation between schaftoside content and precipitation in April and temperature seasonality standard deviation, and a highly significant positive correlation was found between schaftoside content and precipitation in February and March. ②The quality zoning map was drawn depend on general content of polysaccharide and schaftoside as the index of quality. And this research provides scientific location basis for the production regionalization, cultivation bases selection and directive breeding of D. styracifolium. Copyright© by the Chinese Pharmaceutical Association.

  10. About the Western Ecology Division (WED) of EPA's National Health and Environmental Effects Research Laboratory

    EPA Pesticide Factsheets

    The Western Ecology Division (WED) conducts innovative research on watershed ecological epidemiology and the development of tools to achieve sustainable and resilient watersheds for application by stakeholders.

  11. Division B Commission 14: Atomic and Molecular Data

    NASA Astrophysics Data System (ADS)

    Mashonkina, Lyudmila I.; Salama, Farid; Wahlgren, Glenn M.; Allard, France; Barklem, Paul; Beiersdorfer, Peter; Fraser, Helen; Nave, Gillian; Nilsson, Hampus

    2016-04-01

    The main purpose of Commission 14 is to foster interactions between the astronomical community and those conducting research on atoms, molecules, and solid state particles to provide data vital to reducing and analysing astronomical observations and performing theoretical investigations.

  12. 77 FR 65582 - Pfizer Therapeutic Research, Pfizer Worldwide Reasearch & Development Division, Formerly Known as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ... Division, Formerly Known as Warner Lambert Company, Central Nervous System Research Unit (Currently Known... & Development Division, formerly known as Warner Lambert Company, Central Nervous System Research Unit, Global.... The Department has confirmed that the Central Nervous System Research Unit was renamed...

  13. Bayesian Research at the NASA Ames Research Center,Computational Sciences Division

    NASA Technical Reports Server (NTRS)

    Morris, Robin D.

    2003-01-01

    NASA Ames Research Center is one of NASA s oldest centers, having started out as part of the National Advisory Committee on Aeronautics, (NACA). The site, about 40 miles south of San Francisco, still houses many wind tunnels and other aviation related departments. In recent years, with the growing realization that space exploration is heavily dependent on computing and data analysis, its focus has turned more towards Information Technology. The Computational Sciences Division has expanded rapidly as a result. In this article, I will give a brief overview of some of the past and present projects with a Bayesian content. Much more than is described here goes on with the Division. The web pages at http://ic.arc. nasa.gov give more information on these, and the other Division projects.

  14. Division B Commission 14 Working Group: Molecular Data

    NASA Astrophysics Data System (ADS)

    Federman, Steven R.; Bernath, Peter F.; Müller, Holger S. P.

    2016-04-01

    The current report covers the period from the second half of 2011 to late 2014. It is divided into three areas covering rotational, vibrational, and electronic spectroscopy. A signifcant amount of experimental and theoretical work has been accomplished over the past three years, leading to the development and expansion of a number of databases whose links are provided below. Two notable publications have appeared recently: An issue of The Journal of Physical Chemistry A in 2013 honoring the many contributions of Takeshi Oka (J. Phys. Chem. A, 117, pp. 9305-10143); and IAU Symposium 297 on Diffuse Interstellar Bands (Cami & Cox 2014). A number of the relevant papers from these volumes are cited in what follows. Related research on collisions, reactions on grain surfaces, and astrochemistry are not included here.

  15. Accelerator and Fusion Research Division: 1984 summary of activities

    SciTech Connect

    Not Available

    1985-05-01

    During fiscal 1984, major programmatic activities in AFRD continued in each of five areas: accelerator operations, highlighted by the work of nuclear science users, who produced clear evidence for the formation of compressed nuclear matter during heavy-ion collisions; high-energy physics, increasingly dominated by our participation in the design of the Superconducting Super Collider; heavy-ion fusion accelerator research, which focused on the design of a four-beam experiment as a first step toward assessing the promise of heavy-ion inertial-confinement fusion; and research at the Center for X-Ray Optics, which completed its first year of broadly based activities aimed at the exploitation of x-ray and ultraviolet radiation. At the same time, exploratory studies were under way, aimed at investigating major new programs for the division. During the past year, for example, we took a preliminary look at how we could use the Bevatron as an injector for a pair of colliding-beam rings that might provide the first glimpse of a hitherto unobserved state of matter called the quark-gluon plasma. Together with Livermore scientists, we also conducted pioneering high-gain free-electron laser (FEL) experiments and proposed a new FEL-based scheme (called the two-beam accelerator) for accelerating electrons to very high energies. And we began work on the design of the Coherent XUV Facility (CXF), an advanced electron storage ring for the production of intense coherent radiation from either undulators or free-electron lasers.

  16. High Energy Physics Division semiannual report of research activities, July 1, 1991--December 31, 1991

    SciTech Connect

    Schoessow, P.; Moonier, P.; Talaga, R.; Wagner, R.

    1992-04-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of July 1, 1991--December 31, 1991. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  17. High Energy Physics Division semiannual report of research activities, July 1, 1993--December 31, 1993

    SciTech Connect

    Wagner, R.; Moonier, P.; Schoessow, P.; Talaga, R.

    1994-05-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of July 1, 1993--December 31, 1993. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  18. High Energy Physics Division semiannual report of research activities, January 1, 1994--June 30, 1994

    SciTech Connect

    Not Available

    1994-09-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1, 1994-June 30, 1994. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  19. High Energy Physics Division semiannual report of research activities, January 1, 1993--June 30, 1993

    SciTech Connect

    Schoessow, P.; Moonier, P.; Talaga, R.; Wagner, R.

    1993-12-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1, 1993--June 30, 1993. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  20. High Energy Physics Division semiannual report of research activities, July 1, 1991--December 31, 1991

    SciTech Connect

    Schoessow, P.; Moonier, P.; Talaga, R.; Wagner, R.

    1992-04-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of July 1, 1991--December 31, 1991. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  1. High Energy Physics Division semiannual report of research activities, January 1, 1992--June 30, 1992

    SciTech Connect

    Schoessow, P.; Moonier, P.; Talaga, R.; Wagner, R.

    1992-11-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1, 1992--June 30, 1992. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  2. High Energy Physics Division semiannual report of research activities, July 1, 1992--December 30, 1992

    SciTech Connect

    Schoessow, P.; Moonier, P.; Talaga, R.; Wagner, R.

    1993-07-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of July 1, 1992--December 30, 1992. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  3. High Energy Physics Division. Semiannual report of research activities, January 1, 1995--June 30, 1995

    SciTech Connect

    Wagner, R.; Schoessow, P.; Talaga, R.

    1995-12-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1, 1995-July 31, 1995. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  4. High Energy Physics Division semiannual report of research activities, July 1, 1994--December 31, 1994

    SciTech Connect

    Wagner, R.; Schoessow, P.; Talaga, R.

    1995-04-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of July 1, 1994--December 31, 1994. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  5. High Energy Physics division semiannual report of research activities, January 1, 1998--June 30, 1998.

    SciTech Connect

    Ayres, D. S.; Berger, E. L.; Blair, R.; Bodwin, G. T.; Drake, G.; Goodman, M. C.; Guarino, V.; Klasen, M.; Lagae, J.-F.; Magill, S.; May, E. N.; Nodulman, L.; Norem, J.; Petrelli, A.; Proudfoot, J.; Repond, J.; Schoessow, P. V.; Sinclair, D. K.; Spinka, H. M.; Stanek, R.; Underwood, D.; Wagner, R.; White, A. R.; Yokosawa, A.; Zachos, C.

    1999-03-09

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1, 1998 through June 30, 1998. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of Division publications and colloquia are included.

  6. High Energy Physics Division semiannual report of research activities July 1, 1997 - December 31, 1997.

    SciTech Connect

    Norem, J.; Rezmer, R.; Schuur, C.; Wagner, R.

    1998-08-11

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period July 1, 1997--December 31, 1997. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of Division publications and colloquia are included.

  7. High Energy Physics Division semiannual report of research activities, January 1, 1996--June 30, 1996

    SciTech Connect

    Norem, J.; Rezmer, R.; Wagner, R.

    1997-07-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period of January 1 - June 30, 1996. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. List of Division publications and colloquia are included.

  8. Surveys of research in the Chemistry Division, Argonne National Laboratory

    SciTech Connect

    Grazis, B.M.

    1992-11-01

    Research reports are presented on reactive intermediates in condensed phase (radiation chemistry, photochemistry), electron transfer and energy conversion, photosynthesis and solar energy conversion, metal cluster chemistry, chemical dynamics in gas phase, photoionization-photoelectrons, characterization and reactivity of coal and coal macerals, premium coal sample program, chemical separations, heavy elements coordination chemistry, heavy elements photophysics/photochemistry, f-electron interactions, radiation chemistry of high-level wastes (gas generation in waste tanks), ultrafast molecular electronic devices, and nuclear medicine. Separate abstracts have been prepared. Accelerator activites and computer system/network services are also reported.

  9. Surveys of research in the Chemistry Division, Argonne National Laboratory

    SciTech Connect

    Grazis, B.M.

    1992-01-01

    Research reports are presented on reactive intermediates in condensed phase (radiation chemistry, photochemistry), electron transfer and energy conversion, photosynthesis and solar energy conversion, metal cluster chemistry, chemical dynamics in gas phase, photoionization-photoelectrons, characterization and reactivity of coal and coal macerals, premium coal sample program, chemical separations, heavy elements coordination chemistry, heavy elements photophysics/photochemistry, f-electron interactions, radiation chemistry of high-level wastes (gas generation in waste tanks), ultrafast molecular electronic devices, and nuclear medicine. Separate abstracts have been prepared. Accelerator activites and computer system/network services are also reported.

  10. Quarterly Progress Report for the Chemical and Energy Research Section of the Chemical Technology Division: January-March 1998

    SciTech Connect

    Jubin, R.T.

    1999-03-01

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during the period January-March 1998. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within nine major areas of research: Hot Cell Operations, Process Chemistry and Thermodynamics, Molten Salt Reactor Experiment (MSRE) Remediation Studies, Chemistry Research, Biotechnology, Separations and Materials Synthesis, Fluid Structure and Properties, Biotechnology Research, and Molecular Studies.

  11. Structural Biology and Molecular Applications Research

    Cancer.gov

    Part of NCI's Division of Cancer Biology's research portfolio, research and development in this area focuses on enabling technologies, models, and methodologies to support basic and applied cancer research.

  12. High Energy Physics Division semiannual report of research activities, July 1, 1990--December 31, 1990

    SciTech Connect

    Berger, E.; Moonier, P.; May, E.; Norem, J.

    1991-02-01

    A report is presented of research and development activities conducted in the High Energy Physics Division at Argonne National Laboratory during the six month period July 1 through December 31, 1990. Analyses of data from experiments performed by members of the Division are summarized, and the status of experiments taking data and of those being prepared is reviewed. Descriptions are included of research on theoretical and phenomenological topics in particle physics. Progress reports are provided on accelerator research and development, detector research and development, and experimental facilities research. Lists are presented of publications, of colloquia and conference talks, and of significant external community activities of members of the Division.

  13. DCP's Early Detection Research Guides Future Science | Division of Cancer Prevention

    Cancer.gov

    Early detection research funded by the NCI's Division of Cancer Prevention has positively steered both public health and clinical outcomes, and set the stage for findings in the next generation of research. |

  14. EDC RESEARCH AT EPA ATLANTIC ECOLOGY DIVISION: DO ENVIRONMENTAL EDCS IMPACT FISH POPULATIONS

    EPA Science Inventory

    The Atlantic Ecology Division, Office of Research and Development, EP A is a marine laboratory situated on Narragansett Bay, Rhode Island. Researchers at AED are investigating the effects endocrine disrupting chemicals (EDCs) in the aquatic environment might have on reproductive ...

  15. Materials Division research and technology accomplishments for FY 89 and plans for FY 90

    NASA Technical Reports Server (NTRS)

    Brinkley, Kay L.

    1990-01-01

    The research program of the Materials Division is presented as FY-89 accomplishments and FY-90 plans. The accomplishments for each Branch are highlighted and plans are outlined. Publications of the Division are included by Branch. This material will be useful in program coordination with other government organizations, universities, and industries in areas of mutual interest.

  16. Materials Division research and technical accomplishments for FY 1988 and plans for FY 1989

    NASA Technical Reports Server (NTRS)

    Brinkley, Kay L.

    1989-01-01

    The research program of the Materials Division is presented as FY-88 accomplishments and FY-89 plans. The accomplishments for each Branch are highlighted and plans are outlined. Publications of the Division are included by Branch. This material is useful in program coordination with other government organizations, universities, and industry in areas of mutual interest.

  17. Materials Division research and technology accomplishments for FY 87 and plans for FY 88

    NASA Technical Reports Server (NTRS)

    Brinkley, Kay L.

    1988-01-01

    The research program of the Materials Division is presented as FY 87 accomplishments and FY 88 plans. The accomplishments for each Branch are highlighted and plans are outlined. Publications of the Division are included by Branch. This material will be useful in program coordination with other government organizations, universities, and industries in areas of mutual interest.

  18. High Energy Physics Division semiannual report of research activities, July 1, 1996 - December 31, 1996

    SciTech Connect

    Norem, J.; Rezmer, R.; Wagner, R.

    1997-12-01

    This report is divided into the following areas: (1) experimental research program; (2) theoretical research program; (3) accelerator research and development; (4) divisional computing activities; (5) publications; (6) colloquia and conference talks; (7) high energy physics community activities; and (7) High Energy Physics Division research personnel. Summaries are given for individual research programs for activities (1), (2) and (3).

  19. Compartmentalization and Cell Division through Molecular Discreteness and Crowding in a Catalytic Reaction Network

    PubMed Central

    Kamimura, Atsushi; Kaneko, Kunihiko

    2014-01-01

    Explanation of the emergence of primitive cellular structures from a set of chemical reactions is necessary to unveil the origin of life and to experimentally synthesize protocells. By simulating a cellular automaton model with a two-species hypercycle, we demonstrate the reproduction of a localized cluster; that is, a protocell with a growth-division process emerges when the replication and degradation speeds of one species are respectively slower than those of the other species, because of overcrowding of molecules as a natural outcome of the replication. The protocell exhibits synchrony between its division process and replication of the minority molecule. We discuss the effects of the crowding molecule on the formation of primitive structures. The generality of this result is demonstrated through the extension of our model to a hypercycle with three molecular species, where a localized layered structure of molecules continues to divide, triggered by the replication of a minority molecule at the center. PMID:25370530

  20. Consortium for Molecular Characterization of Screen-Detected Lesions Created: Eight Grants Awarded | Division of Cancer Prevention

    Cancer.gov

    The NCI has awarded eight grants to create the Consortium for Molecular Characterization of Screen-Detected Lesions. The consortium has seven molecular characterization laboratories (MCLs) and a coordinating center, and is supported by the Division of Cancer Prevention and the Division of Cancer Biology. | 7 laboratories and a coordinating center focused on identifying screening-detected pre-cancers and early cancers, including within the tumor microenvironment.

  1. Overview of NASA Glenn Research Center's Communications and Intelligent Systems Division

    NASA Technical Reports Server (NTRS)

    Miranda, Felix A.

    2016-01-01

    The Communications and Intelligent Systems Division provides expertise, plans, conducts and directs research and engineering development in the competency fields of advanced communications and intelligent systems technologies for application in current and future aeronautics and space systems.

  2. About the Atlantic Ecology Division (AED) of EPA's National Health and Environmental Effects Research Laboratory

    EPA Pesticide Factsheets

    The Atlantic Ecology Division (AED), conducts innovative research and predictive modeling to assess and forecast the risks of anthropogenic stressors to near coastal waters and their watersheds, to develop tools to support resilient watersheds.

  3. Structures and Dynamics Division research and technology plans for FY 1894 and accomplishments for FY 1982

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1984-01-01

    The Objectives, Expected Results, Approach, and Fiscal Year FY 1984 Milestones for the Structures and Dynamics Division's research programs are examined. The FY 1983 Accomplishments are presented where applicable.

  4. Structures and Dynamics Division research and technology plans, fiscal year, 1981

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1981-01-01

    The objectives, expected results, approach, and FY 81 milestones for the Structures and Dynamics Division's research program are presented. This information will be useful in program coordination with other government organizations in areas of mutual interest.

  5. Bibliography: Occupation and Manpower Research Division, Air Force Human Resources Laboratory (1957-1979).

    DTIC Science & Technology

    1979-12-01

    Psychological Association guidelines for references. This bibliography includes reports accomplished by the Occupation and Manpower Research Division (OR...career programs and reassignment systems. This bibliography has been compiled by chronological year, and within the year, using the American

  6. The Molecular Biology Capstone Assessment: A Concept Assessment for Upper-Division Molecular Biology Students

    ERIC Educational Resources Information Center

    Couch, Brian A.; Wood, William B.; Knight, Jennifer K.

    2015-01-01

    Measuring students' conceptual understandings has become increasingly important to biology faculty members involved in evaluating and improving departmental programs. We developed the Molecular Biology Capstone Assessment (MBCA) to gauge comprehension of fundamental concepts in molecular and cell biology and the ability to apply these concepts in…

  7. The Molecular Biology Capstone Assessment: A Concept Assessment for Upper-Division Molecular Biology Students

    ERIC Educational Resources Information Center

    Couch, Brian A.; Wood, William B.; Knight, Jennifer K.

    2015-01-01

    Measuring students' conceptual understandings has become increasingly important to biology faculty members involved in evaluating and improving departmental programs. We developed the Molecular Biology Capstone Assessment (MBCA) to gauge comprehension of fundamental concepts in molecular and cell biology and the ability to apply these concepts in…

  8. About Supportive and Palliative Care Research | Division of Cancer Prevention

    Cancer.gov

    The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research). |

  9. Accelerator & Fusion Research Division 1991 summary of activities

    SciTech Connect

    Not Available

    1991-12-01

    This report discusses research projects in the following areas: Heavy-ion fusion accelerator research; magnetic fusion energy; advanced light source; center for x-ray optics; exploratory studies; superconducting magnets; and bevalac operations.

  10. Accelerator Fusion Research Division 1991 summary of activities

    SciTech Connect

    Berkner, Klaus H.

    1991-12-01

    This report discusses research projects in the following areas: Heavy-ion fusion accelerator research; magnetic fusion energy; advanced light source; center for x-ray optics; exploratory studies; superconducting magnets; and bevalac operations.

  11. Accelerator and fusion research division. 1992 Summary of activities

    SciTech Connect

    Not Available

    1992-12-01

    This report contains brief discussions on research topics in the following area: Heavy-Ion Fusion Accelerator Research; Magnetic Fusion Energy; Advanced Light Source; Center for Beam Physics; Superconducting Magnets; and Bevalac Operations.

  12. NCI Community Oncology Research Program Approved | Division of Cancer Prevention

    Cancer.gov

    On June 24, 2013, the National Cancer Institute (NCI) Board of Scientific Advisors approved the creation of the NCI Community Oncology Research Program (NCORP). NCORP will bring state-of-the art cancer prevention, control, treatment and imaging clinical trials, cancer care delivery research, and disparities studies to individuals in their own communities. |

  13. Ecological Research Division Theoretical Ecology Program. [Contains abstracts

    SciTech Connect

    Not Available

    1990-10-01

    This report presents the goals of the Theoretical Ecology Program and abstracts of research in progress. Abstracts cover both theoretical research that began as part of the terrestrial ecology core program and new projects funded by the theoretical program begun in 1988. Projects have been clustered into four major categories: Ecosystem dynamics; landscape/scaling dynamics; population dynamics; and experiment/sample design.

  14. Current Nursing Research Grants Supported by the Division of Nursing.

    ERIC Educational Resources Information Center

    National Institutes of Health (DHEW), Bethesda, MD. Div. of Nursing.

    The United States Public Health Service Nursing Research Project Grants established in 1955, support studies dealing with all aspects of nursing practice, organization and delivery of nursing services to the patient, nursing as an occupation, and ways of communicating research findings. Intended as a means of sharing information about ongoing…

  15. Applied Science Division annual report, Environmental Research Program FY 1983

    SciTech Connect

    Cairns, E.J.; Novakov, T.

    1984-05-01

    The primary concern of the Environmental Research Program is the understanding of pollutant formation, transport, and transformation and the impacts of pollutants on the environment. These impacts include global, regional, and local effects on the atmosphere and hydrosphere, and on certain aspects of human health. This multidisciplinary research program includes fundamental and applied research in physics, chemistry, engineering, and biology, as well as research on the development of advanced methods of measurement and analysis. During FY 1983, research concentrated on atmospheric physics and chemistry, applied physics and laser spectroscopy, combustion theory and phenomena, environmental effects of oil shale processing, freshwater ecology and acid precipitation, trace element analysis for the investigation of present and historical environmental impacts, and a continuing survey of instrumentation for environmental monitoring.

  16. Applied Science Division annual report, Environmental Research Program FY 1984

    SciTech Connect

    Cairns, E.J.; Novakov, T.

    1985-03-01

    The objective of the Environmental Research Program is to understand the formation, transformation, transport, and effects of energy-related pollutants on the environment. The effects studied include those on global, regional, and local scales and involve the atmosphere, hydrosphere, and biosphere. This multidisciplinary research program includes fundamental and applied research in physics, chemistry, engineering, and biology, as well as research on the development of advanced methods of measurement and analysis. During FY 1984, research concentrated on atmospheric physics and chemistry, applied physics and laser spectroscopy, combustion theory and phenomena, environmental effects of oil shale processing, toxicology studies of biological systems, and trace element analysis for the investigation of present and historical environmental impacts.

  17. Beyond division: convergences between postmodern qualitative research and family therapy.

    PubMed

    De Haene, Lucia

    2010-01-01

    Starting from examples of postmodern research and therapeutic practice, we raise the question on the role of the research-therapy dichotomy within these approaches. The article aims to show the profound convergence between postmodern ethnographic research and constructionist, collaborative therapeutic approaches on a double, epistemological and practice level. First, we point out their converging development toward narrative and constructionist epistemologies. Second, an inquiry into the core features of these disciplinary activities' goal, process, and expert role reveals their profound convergence into a dialogical practice in which the boundaries between research and therapy are radically transgressed. We conclude by questioning the implications and acceptability of this convergence for researchers' and therapists' understanding of their practices.

  18. Structures and Dynamics Division: Research and technology plans for FY 1983 and accomplishments for FY 1982

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1983-01-01

    The objectives, expected results, approach, and milestones for research projects of the IPAD Project Office and the impact dynamics, structural mechanics, and structural dynamics branches of the Structures and Dynamics Division are presented. Research facilities are described. Topics covered include computer aided design; general aviation/transport crash dynamics; aircraft ground performance; composite structures; failure analysis, space vehicle dynamics; and large space structures.

  19. Structures and Dynamics Division research and technology plans for FY 1988 and accomplishments for FY 1987

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1988-01-01

    Presented are the Objectives, FY 1988 Plans, Approach, and FY 1988 Milestones for the Structures and Dynamics Division (Langley Research Center) research programs. FY 1987 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  20. Advanced Reactor Safety Research Division. Quarterly progress report, January 1-March 31, 1980

    SciTech Connect

    Agrawal, A.K.; Cerbone, R.J.; Sastre, C.

    1980-06-01

    The Advanced Reactor Safety Research Programs quarterly progress report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the USNRC Division of Reactor Safety Research. The projects reported each quarter are the following: HTGR Safety Evaluation, SSC Code Development, LMFBR Safety Experiments, and Fast Reactor Safety Code Validation.

  1. Water Reactor Safety Research Division quarterly progress report, January 1-March 31, 1980

    SciTech Connect

    Romano, A.J.

    1980-06-01

    The Water Reactor Safety Research Programs Quarterly Report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the USNRC Division of Reactor Safety Research. The projects reported each quarter are the following: LWR Thermal Hydraulic Development, Advanced Code Evaluation, TRAC Code Assessment, and Stress Corrosion Cracking of PWR Steam Generator Tubing.

  2. Water Reactor Safety Research Division. Quarterly progress report, April 1-June 30, 1980

    SciTech Connect

    Abuaf, N.; Levine, M.M.; Saha, P.; van Rooyen, D.

    1980-08-01

    The Water Reactor Safety Research Programs quarterly report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the USNRC Division of Reactor Safety Research. The projects reported each quarter are the following: LWR Thermal Hydraulic Development, Advanced Code Evlauation, TRAC Code Assessment, and Stress Corrosion Cracking of PWR Steam Generator Tubing.

  3. Advanced Reactor Safety Research Division. Quarterly progress report, April 1-June 30, 1980

    SciTech Connect

    Romano, A.J.

    1980-01-01

    The Advanced Reactor Safety Research Programs Quarterly Progress Report describes current activities and technical progress in the programs at Brookhaven National Laboratory sponsored by the USNRC Division of Reactor Safety Research. The projects reported each quarter are the following: HTGR safety evaluation, SSC Code Development, LMFBR Safety Experiments, and Fast Reactor Safety Code Validation.

  4. Accelerator and Fusion Research Division: 1987 summary of activities

    SciTech Connect

    Not Available

    1988-04-01

    An overview of the design and the initial studies for the Advanced Light Source is given. The research efforts for the Center for X-Ray Optics include x-ray imaging, multilayer mirror technology, x-ray sources and detectors, spectroscopy and scattering, and synchrotron radiation projects. The Accelerator Operations highlights include the research by users in nuclear physics, biology and medicine. The upgrade of the Bevalac is also discussed. The High Energy Physics Technology review includes the development of superconducting magnets and superconducting cables. A review of the Heavy-Ion Fusion Accelerator Research is also presented. The Magnetic Fusion Energy research included the development of ion sources, accelerators for negative ions, diagnostics, and theoretical plasma physics. (WRF)

  5. About the Cancer Biomarkers Research Group | Division of Cancer Prevention

    Cancer.gov

    The Cancer Biomarkers Research Group promotes research to identify, develop, and validate biological markers for early cancer detection and cancer risk assessment. Activities include development and validation of promising cancer biomarkers, collaborative databases and informatics systems, and new technologies or the refinement of existing technologies. NCI DCP News Note Consortium on Imaging and Biomarkers (CIB) Created: Eight Grants Awarded to Improve Accuracy of Cancer Screening, Detection, and Diagnosis |

  6. Environmental Sciences Division: Summaries of research in FY 1995

    SciTech Connect

    1996-09-01

    This report focuses on research in global change, as well as environmental remediation. Global change research investigates the following: distribution and balance of radiative heat energy; identification of the sources and sinks of greenhouse gases; and prediction of changes in the climate and concomitant ecological effects. Environmental remediation develops the basic understanding needed to remediate soils, sediments, and ground water that have undergone radioactive and chemical contamination.

  7. Quarterly progress report for the Chemical and Energy Research Section of the Chemical Technology Division: July--September 1997

    SciTech Connect

    Jubin, R.T.

    1998-07-01

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during the period July--September 1997. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within nine major areas of research: Hot Cell Operations, Process Chemistry and Thermodynamics, Molten Salt Reactor Experiment (MSRE) Remediation Studies, Chemistry Research, Biotechnology, Separations and Materials Synthesis, Fluid Structure and Properties, Biotechnology Research, and Molecular Studies. The name of a technical contact is included with each task described, and readers are encouraged to contact these individuals if they need additional information.

  8. Materials and Molecular Research Division annual report 1982

    SciTech Connect

    Not Available

    1983-05-01

    This report is divided into: materials sciences, chemical sciences, nuclear sciences, fossil energy, advanced isotope separation technology (AISI), energy storage, magnetic fusion energy (MFE), nuclear waste management, and work for others (WFO). Separate abstracts have been prepared for all except AIST, MFE, and WFO. (DLC)

  9. Materials and Molecular Research Division annual report 1983

    SciTech Connect

    Searcy, A.W.; Muller, R.H.; Peterson, C.V.

    1984-07-01

    Progress is reported in the following fields: materials sciences (metallurgy and ceramics, solid-state physics, materials chemistry), chemical sciences (fundamental interactions, processes and techniques), actinide chemistry, fossil energy, electrochemical energy storage systems, superconducting magnets, semiconductor materials and devices, and work for others. (DLC)

  10. Materials and Molecular Research Division. Annual report 1981

    SciTech Connect

    Not Available

    1982-08-01

    Progress is reported in the areas of materials sciences, chemical sciences, nuclear sciences, fossil energy, advanced (laser) isotope separation technology, energy storage, superconducting magnets, and nuclear waste management. Work for others included phase equilibria for coal gasification products and ..beta..-alumina electrolytes for storage batteries. (DLC)

  11. Instrumentation and Controls Division Overview: Sensors Development for Harsh Environments at Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Zeller, Mary V.; Lei, Jih-Fen

    2002-01-01

    The Instrumentation and Controls Division is responsible for planning, conducting and directing basic and applied research on advanced instrumentation and controls technologies for aerospace propulsion and power applications. The Division's advanced research in harsh environment sensors, high temperature high power electronics, MEMS (microelectromechanical systems), nanotechnology, high data rate optical instrumentation, active and intelligent controls, and health monitoring and management will enable self-feeling, self-thinking, self-reconfiguring and self-healing Aerospace Propulsion Systems. These research areas address Agency challenges to deliver aerospace systems with reduced size and weight, and increased functionality and intelligence for future NASA missions in advanced aeronautics, economical space transportation, and pioneering space exploration. The Division also actively supports educational and technology transfer activities aimed at benefiting all humankind.

  12. QA RESOURCE MATERIALS TO ASSIST IN DEVELOPING AND WRITING RESEARCH PLANS AT A USEPA OFFICE OF RESEARCH AND DEVELOPMENT DIVISION

    EPA Science Inventory

    In the process of adapting the Agency's Data Quality Objectives Workshop for presentation at an ORD Research Facility, ownership and consensus approval of the presentation by the Division's research staff was sought. Three groups of researchers, at various levels of responsibilit...

  13. QA RESOURCE MATERIALS TO ASSIST IN DEVELOPING AND WRITING RESEARCH PLANS AT A USEPA OFFICE OF RESEARCH AND DEVELOPMENT DIVISION

    EPA Science Inventory

    In the process of adapting the Agency's Data Quality Objectives Workshop for presentation at an ORD Research Facility, ownership and consensus approval of the presentation by the Division's research staff was sought. Three groups of researchers, at various levels of responsibilit...

  14. NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention

    Cancer.gov

    The NCI Community Oncology Research Program (NCORP) is a national network of cancer care investigators, providers, academia, and other organizations that care for diverse populations in health systems. View the list of publications from NCORP. | Clinical Trials network of cancer care professionals who care for diverse populations across the U.S.

  15. Structural mechanics division research and technology accomplishments for CY 1992 and plans for CY 1993

    NASA Astrophysics Data System (ADS)

    Malone, John B.

    1993-11-01

    The purpose of this report is to present the Structural Mechanics Division's research accomplishments for C.Y. 1992 and plans for C.Y. 1993. The technical mission and goals of the division and its constituent research branches are described. The work under each branch is described in terms of highlights of accomplishments during the past year and plans for the current year as they relate to branch long range goals. This information is useful in program coordination with other government organizations, universities, and industry in areas of mutual interest.

  16. Structural mechanics division research and technology accomplishments for CY 1992 and plans for CY 1993

    NASA Technical Reports Server (NTRS)

    Malone, John B.

    1993-01-01

    The purpose of this report is to present the Structural Mechanics Division's research accomplishments for C.Y. 1992 and plans for C.Y. 1993. The technical mission and goals of the division and its constituent research branches are described. The work under each branch is described in terms of highlights of accomplishments during the past year and plans for the current year as they relate to branch long range goals. This information is useful in program coordination with other government organizations, universities, and industry in areas of mutual interest.

  17. Minority University Research and Education Division (MURED) Update

    NASA Technical Reports Server (NTRS)

    Malone, John

    2000-01-01

    Program priorities include: (1) Expand and advance NASA's scientific and technological base by building on prior year's efforts in research and academic infrastructure; (2) Increase exposure to NASA's unique mission and facilities by developing closer relationships with NASA Strategic Enterprises; (3) Increase involvement in competitive peer review and merit selection processes; (4) Contribute significantly to the Agency's strategic goals and objectives; (5) Create systemic and sustainable change through partnerships and programs that enhance research and education programs; (6) Prepare faculty and students at HBCU's for NASA-related fields and increase number of students that enter and successfully complete degrees in NASA-related fields; (7) Establish measurable program goals and objectives; and (8) Improve financial management performance.

  18. Supportive and Palliative Care Research | Division of Cancer Prevention

    Cancer.gov

    Supportive and palliative care research includes studies to prevent or treat the acute and chronic symptoms and morbidities related to cancer and its treatment, and to examine the effects of cancer and its treatment on quality of life and psychosocial issues and treatment strategies at the end of life. Active Projects can range from caregiver issues to geriatrics, physical functioning to cognitive dysfunction. | Examining symptoms and morbidities related to cancer, its treatment, quality of life and end of life.

  19. Combustion research in the Internal Fluid Mechanics Division

    NASA Technical Reports Server (NTRS)

    Mularz, Edward J.

    1986-01-01

    The goal of this research is to bring computational fluid dynamics to a state of practical application for the aircraft engine industry. The approach is to have a strongly integrated computational and experimental program for all the disciplines associated with the gas turbine and other aeropropulsion systems by advancing the understanding of flow physics, heat transfer, and combustion processes. The computational and experimental research is integrated in the following way: the experiments that are performed provide an empirical data set so that physical models can be formulated to describe the processes that are occurring - for example, turbulence or chemical reaction. These experiments also form a data base for those who are doing code development by providing experimental data against which the codes can be verified and assesed. Models are generated as closure to some of the numerical codes, and they also provide physical insight for experiments. At the same time, codes which solve the complete Navier-Stokes equations can be used as a kind of numerical experiment from which far more extensive data can be obtained than ever could be obtained experimentally. This could provide physical insight into the complex processes that are taking place. These codes are also exercised against experimental data to assess the accuracy and applicability of models.

  20. Catalog of research projects at Lawrence Berkeley Laboratory, 1985

    SciTech Connect

    Not Available

    1985-01-01

    This Catalog has been created to aid in the transfer of technology from the Lawrence Berkeley Laboratory to potential users in industry, government, universities, and the public. The projects are listed for the following LBL groups: Accelerator and Fusion Research Division, Applied Science Division, Biology and Medicine Division, Center for Advanced Materials, Chemical Biodynamics Division, Computing Division, Earth Sciences Division, Engineering and Technical Services Division, Materials and Molecular Research Division, Nuclear Science Division, and Physics Division.

  1. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Cancer.gov

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health, and the U.S. Department of Agriculture’s (U.S.D.A.) Beltsville Human Nutrition Research Center are offering a one-week educational opportunity in "Nutrition and Cancer Prevention Research" for individuals with a sustained commitment to nutrition and health promotion. |

  2. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Cancer.gov

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health, and the U.S. Department of Agriculture’s Beltsville Human Nutrition Research Center are offering a one-week educational opportunity in Nutrition and Cancer Prevention Research for individuals with a sustained commitment to nutrition and health promotion. |

  3. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Cancer.gov

    The Nutritional Science Research Group in the Division of Cancer Prevention at the National Cancer Institute, National Institutes of Health and the Department of Nutrition at the Clinical Center, National Institutes of Health, and the US Department of Agriculture's Beltsville Human Nutrition Research Center are offering a one week educational opportunity in "Nutrition and Cancer Prevention Research" for individuals with a sustained commitment to nutrition and health promotion. |

  4. Loads and aeroelasticity division research and technology accomplishments for FY 1985 and plans for FY 1986

    NASA Technical Reports Server (NTRS)

    Gardner, J. E.; Dixon, S. C.

    1986-01-01

    The Langley Research Center Loads and Aeroelasticity Division's research accomplishments for FY85 and research plans for FY86 are presented. The rk under each branch (technical area) will be described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  5. Molecular and social regulation of worker division of labour in fire ants.

    PubMed

    Manfredini, Fabio; Lucas, Christophe; Nicolas, Michael; Keller, Laurent; Shoemaker, Dewayne; Grozinger, Christina M

    2014-02-01

    Reproductive and worker division of labour (DOL) is a hallmark of social insect societies. Despite a long-standing interest in worker DOL, the molecular mechanisms regulating this process have only been investigated in detail in honey bees, and little is known about the regulatory mechanisms operating in other social insects. In the fire ant Solenopsis invicta, one of the most studied ant species, workers are permanently sterile and the tasks performed are modulated by the worker's internal state (age and size) and the outside environment (social environment), which potentially includes the effect of the queen presence through chemical communication via pheromones. However, the molecular mechanisms underpinning these processes are unknown. Using a whole-genome microarray platform, we characterized the molecular basis for worker DOL and we explored how a drastic change in the social environment (i.e. the sudden loss of the queen) affects global gene expression patterns of worker ants. We identified numerous genes differentially expressed between foraging and nonforaging workers in queenright colonies. With a few exceptions, these genes appear to be distinct from those involved in DOL in bees and wasps. Interestingly, after the queen was removed, foraging workers were no longer distinct from nonforaging workers at the transcriptomic level. Furthermore, few expression differences were detected between queenright and queenless workers when we did not consider the task performed. Thus, the social condition of the colony (queenless vs. queenright) appears to impact the molecular pathways underlying worker task performance, providing strong evidence for social regulation of DOL in S. invicta. Published 2013. This article is a U.S. Government work and is in the public domain in the U.S.A.

  6. Structures and Dynamics Division research and technology plans for FY 1985 and accomplishments for FY 1984

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1985-01-01

    The objectives, FY 1985 plans, approach, and FY 1985 milestones for the Structures and Dynamics Division's research programs are presented. The FY 1984 accomplishments are presented where applicable. This information is useful in program coordination with other government organizations in areas of mutual interest.

  7. Structures and Dynamics Division research and technology plans for FY 1986 and accomplishments for FY 1985

    NASA Technical Reports Server (NTRS)

    Bales, K. S.

    1986-01-01

    Presented are the Objectives, FY 1986 Plans, Approach, and FY 1986 Milestones for the Structures and Dynamics Division's research programs. FY 1985 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  8. Structures and Dynamics Division research and technology plans for FY 1987 and accomplishments for FY 1986

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1987-01-01

    This paper presents the Objectives, FY 1987 Plans, Approach, and FY 1987 Milestones for the Structures and Dynamics Division's research programs. FY 1986 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  9. NCI Community Oncology Research Program Clinical Trials | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  10. Los Alamos Life Sciences Division's biomedical and environmental research programs. Progress report, January-December 1980

    SciTech Connect

    Holland, L.M.; Stafford, C.G.; Bolen, S.K.

    1981-09-01

    Highlights of research progress accomplished in the Life Sciences Division during the year ending December 1980 are summarized. Reports from the following groups are included: Toxicology, Biophysics, Genetics; Environmental Pathology, Organic Chemistry, and Environmental Sciences. Individual abstracts have been prepared for 46 items for inclusion in the Energy Data Base. (RJC)

  11. Active NCI Community Oncology Research Program Grants | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  12. Completed Supportive and Palliative Care Research Grants | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  13. Supportive and Palliative Care Research Clinical Trials | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  14. Health and Safety Research Division progress report for the period October 1, 1991--March 31, 1993

    SciTech Connect

    Berven, B.A.

    1993-09-01

    This is a progress report from the Health and Safety Research Division of Oak Ridge National Laboratory. Information is presented in the following sections: Assessment Technology, Biological and Radiation Physics, Chemical Physics, Biomedical and Environmental Information Analysis, Risk Analysis, Center for Risk Management, Associate Laboratories for Excellence in Radiation Technology (ALERT), and Contributions to National and Lead Laboratory Programs and Assignments--Environmental Restoration.

  15. Supportive and Palliative Care Research Funding Opportunities | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  16. Active Supportive and Palliative Care Research Grants | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  17. Structural Mechanics Division research and technology plans for FY 1990 and accomplishments for FY 1989

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1990-01-01

    The Objectives, FY 1990 Plans, Approach, and FY 1990 Milestones for the Structural Mechanics Division's research programs are presented. FY 1989 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  18. Radiological and Environmental Research Division annual report, July 1979-June 1980. [Lead abstract

    SciTech Connect

    Rowland, R.E.; Stehney, A.F.

    1981-05-01

    Separate abstracts were prepared for 19 of the 33 papers presented by the Center for Human Radiobiology for the Radiological and Environmental Research Division Annual Report. The 14 items not included are abstracts only and deal with the mechanisms and dosimetry for induction of malignancies by radium. (KRM)

  19. Research and technology plans for FY 1989 and accomplishments for FY 1988. [Structural Mechanics Division

    SciTech Connect

    Bales, K.S.

    1989-04-01

    The Objectives, FY 1989 Plans, Approach, and FY 1989 Milestones for the Structural Mechanics Division's research programs are presented. Fiscal year 1988 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  20. Research and technology plans for FY 1989 and accomplishments for FY 1988. [Structural Mechanics Division

    NASA Technical Reports Server (NTRS)

    Bales, Kay S.

    1989-01-01

    The Objectives, FY 1989 Plans, Approach, and FY 1989 Milestones for the Structural Mechanics Division's research programs are presented. Fiscal year 1988 Accomplishments are presented where applicable. This information is useful in program coordination with other governmental organizations in areas of mutual interest.

  1. 75 FR 32792 - Office of Public Health Support; Division of Planning, Evaluation & Research Native American...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... HUMAN SERVICES Indian Health Service Office of Public Health Support; Division of Planning, Evaluation... American Research Centers for Health (NARCH). Due to the complexity of factors contributing to the health... collaborative efforts of the agencies of the Department of Health and Human Services (HHS) and the collaboration...

  2. Active Barrett's Esophagus Translational Research Network Grants | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  3. Molecular dynamics simulations of high energy cascade in ordered alloys: Defect production and subcascade division

    NASA Astrophysics Data System (ADS)

    Crocombette, Jean-Paul; Van Brutzel, Laurent; Simeone, David; Luneville, Laurence

    2016-06-01

    Displacement cascades have been calculated in two ordered alloys (Ni3Al and UO2) in the molecular dynamics framework using the CMDC (Cell Molecular Dynamics for Cascade) code (J.-P. Crocombette and T. Jourdan, Nucl. Instrum. Meth. B 352, 9 (2015)) for energies ranking between 0.1 and 580 keV. The defect production has been compared to the prediction of the NRT (Norgett, Robinson and Torrens) standard. One observes a decrease with energy of the number of defects compared to the NRT prediction at intermediate energies but, unlike what is commonly observed in elemental solids, the number of produced defects does not always turn to a linear variation with ballistic energy at high energies. The fragmentation of the cascade into subcascades has been studied through the analysis of surviving defect pockets. It appears that the common knowledge equivalence of linearity of defect production and subcascades division does not hold in general for alloys. We calculate the average number of subcascades and average number of defects per subcascades as a function of ballistic energy. We find an unexpected variety of behaviors for these two average quantities above the threshold for subcascade formation.

  4. Molecular Insights into Division of Single Human Cancer Cells in On-Chip Transparent Microtubes

    PubMed Central

    2016-01-01

    In vivo, mammalian cells proliferate within 3D environments consisting of numerous microcavities and channels, which contain a variety of chemical and physical cues. External environments often differ between normal and pathological states, such as the unique spatial constraints that metastasizing cancer cells experience as they circulate the vasculature through arterioles and narrow capillaries, where they can divide and acquire elongated cylindrical shapes. While metastatic tumors cause most cancer deaths, factors impacting early cancer cell proliferation inside the vasculature and those that can promote the formation of secondary tumors remain largely unknown. Prior studies investigating confined mitosis have mainly used 2D cell culture systems. Here, we mimic aspects of metastasizing tumor cells dividing inside blood capillaries by investigating single-cell divisions of living human cancer cells, trapped inside 3D rolled-up, transparent nanomembranes. We assess the molecular effects of tubular confinement on key mitotic features, using optical high- and super-resolution microscopy. Our experiments show that tubular confinement affects the morphology and dynamics of the mitotic spindle, chromosome arrangements, and the organization of the cell cortex. Moreover, we reveal that membrane blebbing and/or associated processes act as a potential genome-safety mechanism, limiting the extent of genomic instability caused by mitosis in confined circumstances, especially in tubular 3D microenvironments. Collectively, our study demonstrates the potential of rolled-up nanomembranes for gaining molecular insights into key cellular events occurring in tubular 3D microenvironments in vivo. PMID:27267364

  5. Structural dynamics division research and technology accomplishments for FY 1989 and plans for FY 1990

    NASA Technical Reports Server (NTRS)

    Smith, Jacqueline G.; Gardner, James E.

    1990-01-01

    The purpose is to present the Structural Dynamics Division's research accomplishments for FY 1989 and research plans for FY 1990. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  6. Structural dynamics division research and technology accomplishments for FY 1993 and plans for FY 1994

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1994-01-01

    The purpose is to present the Structural Dynamics Division's research accomplishments for F.Y. 1993 and research plans for F.Y. 1994. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5-year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  7. Loads and aeroelasticity division research and technology accomplishments for FY 1987 and plans for FY 1988

    NASA Technical Reports Server (NTRS)

    Dixon, S. C.; Gardner, James E.

    1988-01-01

    The purpose of this paper is to present the Loads and Aeroelasticity Division's research accomplishments for FY87 and research plans for FY88. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to five year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  8. Structural dynamics division research and technology accomplishments for FY 1988 and plans for FY 1989

    NASA Technical Reports Server (NTRS)

    Gardner, James E.

    1989-01-01

    The purpose of this paper is to present the Structural Dynamics Division's research accomplishments for FY 1988 and research plans for FY 1989. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and plans for the current year as they relate to five-year plans for each area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  9. High Energy Physics Division semiannual report of research activities. Semi-annual progress report, July 1, 1995--December 31, 1995

    SciTech Connect

    Norem, J.; Bajt, D.; Rezmer, R.; Wagner, R.

    1996-10-01

    This report describes the research conducted in the High Energy Physics Division of Argonne National Laboratory during the period July 1, 1995 - December 31, 1995. Topics covered here include experimental and theoretical particle physics, advanced accelerator physics, detector development, and experimental facilities research. Lists of division publications and colloquia are included.

  10. Health and Safety Research Division progress report, October 1, 1988--March 31, 1990

    SciTech Connect

    Not Available

    1990-09-01

    The Health and Safety Research Division (HASRD) of the Oak Ridge National Laboratory (ORNL) continues to maintain an outstanding program of basic and applied research displaying a high level of creativity and achievement as documented by awards, publications, professional service, and successful completion of variety of projects. Our focus is on human health and the scientific basis for measurement and assessment of health-related impacts of energy technologies. It is our custom to publish a division progress report every 18 months that summarizes our programmatic progress and other measures of achievement over the reporting period. Since it is not feasible to summarize in detail all of our work over the period covered by this report (October 1, 1988, to March 30, 1990), we intend this document to point the way to the expensive open literature that documents our findings. During the reporting period the Division continued to maintain strong programs in its traditional areas of R D, but also achieved noteworthy progress in other areas. Much of the Division's work on site characterization, development of new field instruments, compilation of data bases, and methodology development fits into this initiative. Other new work in tunneling microscopy in support of DOE's Human Genome Program and the comprehensive R D work related to surface-enhanced Raman spectroscopy have attained new and exciting results. These examples of our progress and numerous other activities are highlighted in this report.

  11. Highlighting ten years of physics education research in the upper division

    NASA Astrophysics Data System (ADS)

    Ambrose, Bradley

    2015-04-01

    The field of Physics Education Research (PER) has for over thirty years provided insights into student thinking and guided the development and assessment of reformed teaching strategies and practices in introductory physics courses. In the last decade or so, researchers have expanded the domain of such investigations to upper-division courses where undergraduate majors study more advanced content and begin to see themselves as future physicists. The upcoming Focused Collection on Upper Division PER brings together work from researchers active in these new frontiers of PER. In this presentation we provide an overview of the studies in this collection, which offer to the PER and greater physics education communities: new insights about the thinking, behavior, and beliefs of students in the upper division; new tools to innovate instruction, assess student learning, and evaluate teaching effectiveness; and groundbreaking studies of identity development and ``thinking like a physicist'' among physics majors. In this session we also recognize the ten-year anniversary of Physical Review Special Topics: Physics Education Research, an occasion that we will celebrate with an informal reception immediately following the conclusion of this invited session.

  12. Dr. Worta McCaskill-Stevens Named Recipient of AACR Minorities in Cancer Research Award | Division of Cancer Prevention

    Cancer.gov

    Worta McCaskill-Stevens, MD, MS, Chief of the Community Oncology and Prevention Trials Research Group, NCI Division of Cancer Prevention, was named the recipient of the 2016 American Association for Cancer Research Jane Cooke Wright Memorial Lectureship. |

  13. Los Alamos Life Sciences Division's biomedical and environmental research programs. Progress report, January-December 1981. [Leading abstract

    SciTech Connect

    Holland, L.M.; Stafford, C.G.

    1982-10-01

    This report summarizes research and development activities of the Los Alamos Life Sciences Division's Biomedical and Environmental Research program for the calendar year 1981. Individual reports describing the current status of projects have been entered individually into the data base.

  14. Loads and Aeroelasticity Division research and technology accomplishments for FY 1984 and plans for FY 1985

    NASA Technical Reports Server (NTRS)

    Gardner, J. E.; Dixon, S. C.

    1985-01-01

    The loads and aeroelasticity divisions research accomplishments are presented. The work under each branch or technical area, described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  15. Research on Geographical Environment Unit Division Based on the Method of Natural Breaks (Jenks)

    NASA Astrophysics Data System (ADS)

    Chen, J.; Yang, S. T.; Li, H. W.; Zhang, B.; Lv, J. R.

    2013-11-01

    Zoning which is to divide the study area into different zones according to their geographical differences at the global, national or regional level, includes natural division, economic division, geographical zoning of departments, comprehensive zoning and so on. Zoning is of important practical significance, for example, knowing regional differences and characteristics, regional research and regional development planning, understanding the favorable and unfavorable conditions of the regional development etc. Geographical environment is arising from the geographical position linkages. Geographical environment unit division is also a type of zoning. The geographical environment indicators are deeply studied and summed up in the article, including the background, the associated and the potential. The background indicators are divided into four categories, such as the socio-economic, the political and military, the strategic resources and the ecological environment, which can be divided into more sub-indexes. While the sub-indexes can be integrated to comprehensive index system by weighted stacking method. The Jenks natural breaks classification method, also called the Jenks optimization method, is a data classification method designed to determine the best arrangement of values into different classes. This is done by seeking to minimize each class's average deviation from the class mean, while maximizing each class's deviation from the means of the other groups. In this paper, the experiment of Chinese surrounding geographical environment unit division has been done based on the natural breaks (jenks) method, the geographical environment index system and the weighted stacking method, taking South Asia as an example. The result indicates that natural breaks (jenks) method is of good adaptability and high accuracy on the geographical environment unit division. The geographical environment research was originated in the geopolitics and flourished in the geo

  16. Lesbian women and household labor division: A systematic review of scholarly research from 2000 to 2015.

    PubMed

    Brewster, Melanie E

    2017-01-02

    Recent studies have begun to attend to distribution of household labor within same-gender couples compared to heterosexual couples, yet much of the available research with lesbian couples has attempted to superimpose division of household labor frameworks developed with heterosexual couples (e.g., gender role socialization, exchange bargaining theories) to fit the experiences of same-gender couples. Using two academic search databases, the present article provides a systematic review of the available 28 peer-reviewed articles published from 2000-2015 about lesbian partnerships and household labor divisions. Results indicate that lesbian couples engage in a more equal distribution of household labor than heterosexual couples, and that lesbian women often opt to eschew traditional gendered divisions of chores in favor of other factors such as quality of task or ability. The systematic review uncovered notable constraints in the demography of participants (e.g., race, socioeconomic status, geographic location) across studies. Strategies for deepening the depth and breadth of this line of work for future researchers, and implications for relationship satisfaction are also discussed.

  17. Simulation Technology Research Division assessment of the IBM RISC SYSTEM/6000 Model 530 workstation

    SciTech Connect

    Valdez, G.D. ); Halbleib, J.A.; Kensek, R.P.; Lorence, L.J. )

    1990-11-01

    A workstation manufactured by International Business Machines Corporation (IBM) was loaned to the Simulation Technology Research Division for evaluation. We have found that these new UNIX workstations from IBM have superior cost to performance ratios compared to the CRAY supercomputers and Digital's VAX machines. Our appraisal of this workstation included floating-point performance, system and environment functionality, and cost effectiveness. Our assessment was based on a suite of radiation transport codes developed at Sandia that constitute the bulk of our division's computing workload. In this report, we also discuss our experience with features that are unique to this machine such as the AIX operating system and the XLF Fortran Compiler. The interoperability of the RS/6000 workstation with Sandia's network of CRAYs and VAXs was also assessed.

  18. Investigating the Molecular Mechanism of TSO1 Function in Arabidopsis cell division and meristem development

    SciTech Connect

    Zhongchi Liu

    2004-10-01

    Unlike animals, plants are constantly exposed to environmental mutagens including ultraviolet light and reactive oxygen species. Further, plant cells are totipotent with highly plastic developmental programs. An understanding of molecular mechanisms underlying the ability of plants to monitor and repair its DNA and to eliminate damaged cells are of great importance. Previously we have identified two genes, TSO1 and TSO2, from a flowering plant Arabidopsis thaliana. Mutations in these two genes cause callus-like flowers, fasciated shoot apical meristems, and abnormal cell division, indicating that TSO1 and TSO2 may encode important cell cycle regulators. Previous funding from DOE led to the molecular cloning of TSO1, which was shown to encode a novel nuclear protein with two CXC domains suspected to bind DNA. This DOE grant has allowed us to characterize and isolate TSO2 that encodes the small subunit of the ribonucleotide reductase (RNR). RNR comprises two large subunits (R1) an d two small subunits (R2), catalyzes a rate-limiting step in the production of deoxyribonucleotides needed for DNA replication and repair. Previous studies in yeast and mammals indicated that defective RNR often led to cell cycle arrest, growth retardation and p53-dependent apoptosis while abnormally elevated RNR activities led to higher mutation rates. Subsequently, we identified two additional R2 genes, R2A and R2B in the Arabidopsis genome. Using reverse genetics, mutations in R2A and R2B were isolated, and double and triple mutants among the three R2 genes (TSO2, R2A and R2B) were constructed and analyzed. We showed that Arabidopsis tso2 mutants, with reduced dNTP levels, were more sensitive to UV-C. While r2a or r2b single mutants did not exhibit any phenotypes, tso2 r2b double mutants were embryonic lethal and tso2 r2a double mutants were seedling lethal indicating redundant functions among the three R2 genes. Furthermore, tso2 r2a double mutants exhibited increased DNA dam age

  19. Structural dynamics division research and technology accomplishments for FY 1992 and plans for FY 1993

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1993-01-01

    The purpose of this paper is to present the Structural Dynamics Division's research accomplishments for F.Y. 1992 and research plans for F.Y. 1993. The work under each Branch (technical area) is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5-year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest.

  20. Health and Safety Research Division progress report for the period April 1, 1987--September 30, 1988

    SciTech Connect

    Kaye, S.V.

    1989-03-01

    The mission of the Health and Safety Research Division (HASRD) is to provide a sound scientific basis for the measurement and assessment of human health impacts of radiological and chemical substances. Our approach to fulfilling this mission is to conduct a broad program of experimental, theoretical, and field research based on a strong foundation of fundamental physical studies that blend into well-established programs in life sciences. Topics include biomedical screening techniques, biological and chemical sensors, risk assessment, health hazards, dosimetry, nuclear medicine, environmental pollution monitoring, electron-molecule interactions, interphase physics, surface physics, data base management, environmental mutagens, carcinogens, and tetratogens.

  1. Accelerator and Fusion Research Division annual report, October 1981-September 1982. Fiscal year 1982

    SciTech Connect

    Johnson, R.K.; Bouret, C.

    1983-05-01

    This report covers the activities of LBL's Accelerator and Fusion Research Division (AFRD) during 1982. In nuclear physics, the Uranium Beams Improvement Project was concluded early in the year, and experimentation to exploit the new capabilities began in earnest. Technical improvement of the Bevalac during the year centered on a heavy-ion radiofrequency quadrupole (RFQ) as part of the local injector upgrade, and we collaborated in studies of high-energy heavy-ion collision facilities. The Division continued its collaboration with Fermilab to design a beam-cooling system for the Tevatron I proton-antiprotron collider and to engineer the needed cooling components for the antiproton. The high-field magnet program set yet another record for field strength in an accelerator-type dipole magnet (9.2 T at 1.8 K). The Division developed the design for the Advanced Light Source (ALS), a 1.3-GeV electron storage ring designed explicitly (with low beam emittance and 12 long straight sections) to generate high-brilliance synchrotron light from insertion devices. The Division's Magnetic Fusion Energy group continued to support major experiments at the Princeton Plasma Physics Laboratory, the Lawrence Livermore National Laboratory (LLNL), and General Atomic Co. by developing positive-ion-based neutral-beam injectors. Progress was made toward converting our major source-test facility into a long-pulse national facility, the Neutral Beam Engineering Test Facility, which was completed on schedule and within budget in 1983. Heavy Ion Fusion research focused on planning, theoretical studies, and beam-transport experiments leading toward a High Temperature Experiment - a major test of this promising backup approach to fusion energy.

  2. Research on Molecular Sieve Technology.

    ERIC Educational Resources Information Center

    Shah, Dhananjai B.; Hayhurst, David T.

    1985-01-01

    The zeolite synthesis and modification research program at Cleveland State University (Ohio) is described, including program philosophy and objectives, and research facilities. Also considers zeolite synthesis, adsorption on zeolites, kinetics of adsorption, and zeolite catalysis research. (JN)

  3. Research on Molecular Sieve Technology.

    ERIC Educational Resources Information Center

    Shah, Dhananjai B.; Hayhurst, David T.

    1985-01-01

    The zeolite synthesis and modification research program at Cleveland State University (Ohio) is described, including program philosophy and objectives, and research facilities. Also considers zeolite synthesis, adsorption on zeolites, kinetics of adsorption, and zeolite catalysis research. (JN)

  4. Strategic faculty recruitment increases research productivity within an academic university division

    PubMed Central

    Chung, Stephen W.; Clifton, Joanne S.; Rowe, Andrea J.; Finley, Richard J.; Warnock, Garth L.

    2009-01-01

    Background Research is an important mandate for academic surgical divisions. However, there is widespread concern that the current health care climate is leading to a decline in research activity. A University of British Columbia (UBC) academic surgical division attempted to address this concern by strategically recruiting PhD research scientists to prioritize research and develop collaborative research programs. The objective of our study was to determine whether this strategy resulted in increased research productivity. Methods We reviewed the UBC Department of Surgery database to assess research funding obtained by the Division of General Surgery for the years 1994–2004. We searched MEDLINE for peer-reviewed publications by faculty members during this period. Results Research funding increased from a mean of Can$417 292 per year in the 5 years (1994/95–1998/99) before the recruitment of dedicated PhD scientists to a mean of Can$1.3 million per year in the 5 years following the recruitment strategy (1999/2000–2003/04; p = 0.012). Funding for the initial 5 years was Can$2.1 million, including 1 Canadian Institutes of Health Research (CIHR) grant. Funding increased to Can$6.8 million, including 22 CIHR grants over the subsequent 5 years (p < 0.001). Collaborative research led to the awarding of multidisciplinary grants exceeding Can$4 million with divisional members as principle or coprinciple investigators. From 1994/05 to 1998/99, the total number of peer-reviewed publications was 116 (mean 23.2, standard deviation [SD] 7 per year), increasing to 144 from 1999/2000 to 2003/04 (mean 28.8, SD 13 per year). The trend was for publications in journals with higher impact factors in the latter 5-year period. Conclusion Strategic recruitment resulted in increased and sustained research productivity. Interactions between research scientists and clinicians resulted in successful program grant funding support. These results have implications for sustaining the

  5. MOLECULAR ANALYSIS OF HUMAN SPERMATOZOA: POTENTIAL FOR INFERTILITY RESEARCH AND SCREENING

    EPA Science Inventory

    Molecular Analysis of Human Spermatozoa: Potential for Infertility Research and Screening
    David Miller1, David Dix2, Robert Reid3, Susan Wykes3 and Stephen Krawetz3
    1Reproductive Biology Group, University of Leeds, UK
    2Reproductive Toxicology Division, U.S. Environmenta...

  6. MOLECULAR ANALYSIS OF HUMAN SPERMATOZOA: POTENTIAL FOR INFERTILITY RESEARCH AND SCREENING

    EPA Science Inventory

    Molecular Analysis of Human Spermatozoa: Potential for Infertility Research and Screening
    David Miller1, David Dix2, Robert Reid3, Susan Wykes3 and Stephen Krawetz3
    1Reproductive Biology Group, University of Leeds, UK
    2Reproductive Toxicology Division, U.S. Environmenta...

  7. About the Mid-Continent Ecology Division (MED) of EPA's National Health and Environmental Effects Research Laboratory

    EPA Pesticide Factsheets

    The Mid-Continent Ecology Division (MED) conducts innovative research and predictive modeling to document and forecast the effects of pollutants on the integrity of watersheds and freshwater ecosystems.

  8. Advancing research and practice: the revised APA Division 30 definition of hypnosis.

    PubMed

    Elkins, Gary R; Barabasz, Arreed F; Council, James R; Spiegel, David

    2015-01-01

    This article describes the history, rationale, and guidelines for developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. The definition was developed with the aim of being concise, heuristic, and allowing for alternative theories of the mechanisms (to be determined in empirical scientific study). The definition of hypnosis is presented as well as definitions of the following related terms: hypnotic induction, hypnotizability, and hypnotherapy. The implications for advancing research and practice are discussed. The definitions are presented within the article.

  9. Advancing Research and Practice: The Revised APA Division 30 Definition of Hypnosis.

    PubMed

    Elkins, Gary R; Barabasz, Arreed F; Council, James R; Spiegel, David

    2015-04-01

    This article describes the history, rationale, and guidelines for developing a new definition of hypnosis by the Society of Psychological Hypnosis, Division 30 of the American Psychological Association. The definition was developed with the aim of being concise, being heuristic, and allowing for alternative theories of the mechanisms (to be determined in empirical scientific study). The definition of hypnosis is presented as well as definitions of the following related terms: hypnotic induction, hypnotizability, and hypnotherapy. The implications for advancing research and practice are discussed. The definitions are presented within the article.

  10. Chemical Technology Division annual technical report 1997

    SciTech Connect

    1998-06-01

    The Chemical Technology (CMT) Division is a diverse technical organization with principal emphases in environmental management and development of advanced energy sources. The Division conducts research and development in three general areas: (1) development of advanced power sources for stationary and transportation applications and for consumer electronics, (2) management of high-level and low-level nuclear wastes and hazardous wastes, and (3) electrometallurgical treatment of spent nuclear fuel. The Division also performs basic research in catalytic chemistry involving molecular energy resources, mechanisms of ion transport in lithium battery electrolytes, and the chemistry of technology-relevant materials and electrified interfaces. In addition, the Division operates the Analytical Chemistry Laboratory, which conducts research in analytical chemistry and provides analytical services for programs at Argonne National Laboratory (ANL) and other organizations. Technical highlights of the Division`s activities during 1997 are presented.

  11. Quarterly progress report for the Chemical and Energy Research Section of the Chemical Technology Division: October-December 1997

    SciTech Connect

    Jubin, R.T.

    1999-02-01

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during the period October--December 1997. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within six major areas of research: Hot Cell Operations, Process Chemistry and Thermodynamics, Separations and Materials Synthesis, Fluid Structure and Properties, Biotechnology Research, and Molecular Studies. The name of a technical contact is included with each task described, and readers are encouraged to contact these individuals if they need additional information. Activities conducted within the area of Hot Cell Operations included efforts to optimize the processing conditions for Enhanced Sludge Washing of Hanford tank sludge, the testing of candidate absorbers and ion exchangers under continuous-flow conditions using actual supernatant from the Melton Valley Storage Tanks, and attempts to develop a cesium-specific spherical inorganic sorbent for the treatment of acidic high-salt waste solutions. Within the area of Process Chemistry and Thermodynamics, the problem of solids formation in process solutions from caustic treatment of Hanford sludge was addressed and experimental collaborative efforts with Russian scientists to determine the solidification conditions of yttrium barium, and copper oxides from their melts were completed.

  12. The Geosciences Division of the Council on Undergraduate Research (GeoCUR): Supporting Faculty that Mentor Undergraduate Researchers

    NASA Astrophysics Data System (ADS)

    Fox, L. K.; Guertin, L. A.; Manley, P. L.; Fortner, S. K.

    2012-12-01

    Undergraduate research is a proven effective pedagogy that has a number of benefits including: enhancing student learning through mentoring relationships with faculty; increasing retention; increasing enrollment in graduate programs; developing critical thinking, creativity, problem solving and intellectual independence; and, developing an understanding of research methodology. Undergraduate research also has been demonstrated in preparing students for careers. In addition to developing disciplinary and technical expertise, participation in undergraduate research helps students improve communication skills (written, oral, and graphical) and time management. Early involvement in undergraduate research improves retention and, for those engaged at the 2YC level, helps students successfully transfers to 4YC. The Geosciences Division of the Council on Undergraduate Research (GeoCUR) supports faculty in their development of undergraduate research programs at all levels. GeoCUR leads workshops for new and future faculty covering all aspects of undergraduate research including incorporating research into coursework, project design, mentoring students, sustaining programs, and funding sources. GeoCUR members support new faculty by providing a range of services including: peer-review of grant proposals; advice on establishing an undergraduate research program; balancing teaching and research demands; and networking with other geoscientist. GeoCUR has also developed web resources that support faculty and departments in development of undergraduate research programs (http://serc.carleton.edu/NAGTWorkshops/undergraduate_research/index.html). This presentation will describe the services provided by GeoCUR and highlight examples of programs and resources available to geoscientists in all career stages for effective undergraduate research mentoring and development.

  13. A crucial step in cell division identified | Center for Cancer Research

    Cancer.gov

    When cell division doesn’t go according to plan, the resulting daughter cells can become unstable or even cancerous. A team of CCR investigators has now discovered a crucial step required for normal cell division to occur. Read more...

  14. The value of public health research and the division between basic vs. applied science.

    PubMed

    Almeida-Filho, Namoar; Goldbaum, Moisés

    2003-02-01

    We question the movement towards exclusion of population and social health research from the field of science. The background under analysis is contemporary Brazil, where the scientific field that hosts this kind of research is known as Collective Health. First, the problem is formalized on logical grounds, evaluating the pertinence of considering unscientific the many objects and methods of public health research. Secondly, the cases of pulmonary tuberculosis and external causes are brought in as illustrations of the kind of scientific problem faced in health research today. The logical and epistemological basis of different forms of "scientific segregation" based on biomedical reductionism is analyzed, departing from three theses: (i) the ethics of the general application of science; (ii) the inappropriateness of monopolies for objectivity in the sciences; (iii) the specificity of scientific fields. In the current panorama of health research in Brazil, a residual hegemonic position that defends a narrow and specific definition of the object of knowledge was found. The denial of validity and specificity to objects, methods and research techniques that constitute social and population research in health is linked to elements of irrationality in reductionism approaches. Nevertheless, efforts should be directed to overcome this scientific division, in order to develop a pluralist and interdisciplinary national science, committed to the health care realities of our country.

  15. AICD: Advanced Industrial Concepts Division Biological and Chemical Technologies Research Program

    NASA Astrophysics Data System (ADS)

    Petersen, G.; Bair, K.; Ross, J.

    1994-03-01

    The annual summary report presents the fiscal year (FY) 1993 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1993 (ASR 93) contains the following: A program description (including BCTR program mission statement, historical background, relevance, goals and objectives), program structure and organization, selected technical and programmatic highlights for 1993, detailed descriptions of individual projects, and a listing of program output including a bibliography of published work, patents, and awards arising from work supported by BCTR.

  16. AICD -- Advanced Industrial Concepts Division Biological and Chemical Technologies Research Program. 1993 Annual summary report

    SciTech Connect

    Petersen, G.; Bair, K.; Ross, J.

    1994-03-01

    The annual summary report presents the fiscal year (FY) 1993 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). The annual summary report for 1993 (ASR 93) contains the following: A program description (including BCTR program mission statement, historical background, relevance, goals and objectives), program structure and organization, selected technical and programmatic highlights for 1993, detailed descriptions of individual projects, a listing of program output, including a bibliography of published work, patents, and awards arising from work supported by BCTR.

  17. National Research Program of the Water Resources Division, U.S. Geological Survey, Fiscal Year 1993

    USGS Publications Warehouse

    Nichols, Martha L.; Friedman, Linda C.

    1995-01-01

    INTRODUCTION This report, one in a series of annual reports, provides current information about the National Research Program (NRP) of the U.S. Geological Survey's (USGS) Water Resources Division (WRD) during fiscal year 1993. Organized by NRP's six research disciplines, the volume contains a summary of the problem, objective, approach, and progress for each project that was active during fiscal year 1993. It also contains bibliographic information that, because of the long-term nature of the program, covers a 5-year period. The bibliographic information does not include abstracts or informal reports. Rather it contains those reports that are readily available in the form of journal articles, USGS publications, book chapters, or books.

  18. Student research activities in the Technology Assessments Section of the Health and Safety Research Division, Summer 1980

    SciTech Connect

    Chester, R.O.; Roberts, D.A.

    1981-08-01

    Reports summarizing activities of students assigned to the Technology Assessments Section of the Health and Safety Research Division for the summer 1980 are presented. Unless indicated otherwise, each report was written by the student whose work is being described. For each student, the student's supervisor, the name of the program under which the student was brought to ORNL, the academic level of the student, and the name of the ORNL project to which the student was assigned are tabulated. The reports are presented in alphabetical order of the students' last names.

  19. National Science Foundation Division of Ocean Sciences: new opportunities for ocean research

    NASA Astrophysics Data System (ADS)

    Yoder, J. A.; Tenney, A. B.

    2003-04-01

    The mission of the NSF Division of Ocean Sciences (OCE) is to support basic, curiosity-driven research, using a competitive process based on peer-review to guide selection of grants for financial support. OCE is the leading U.S. government source of ocean science funding for academic institutions. OCE supports research in biological, chemical and physical oceanography, and marine geology and geophysics; ocean technology development; dedicated educational activities; large shipboard equipment and shared-use instruments; the U.S. academic research fleet, submersibles, and scientific ocean drilling (ODP/IODP). In our poster, we describe OCE plans for new infrastructure projects to support research, and some of the new research and education programs being developed. Two large ocean science infrastructure projects -- a drilling vessel conversion and the ocean observatories initiative -- have already been approved for possible inclusion in a future NSF budget request. The drilling vessel will contribute to a new international scientific ocean drilling program to replace the Ocean Drilling Program (ODP), which ends in 2003. We continue to refine our plan for the Ocean Observatories Initiative (OOI), another large infrastructure program that will provide a continuous ocean presence to advance research and education. We are also working closely with the Office of Naval Research and other agency partners to implement a federal plan to renew the academic fleet. We continue to initiate new research and education programs. Two recent examples are Centers for Ocean Science Education Excellence (COSEE) and Centers for Oceans and Human Health; the latter supported jointly with the National Institute for Environmental Health Sciences. COSEE is building a nationally coordinated effort in ocean science education designed to integrate ocean science research into delivery of high-quality education programs in the ocean sciences. The Centers for Oceans and Human Health program

  20. Biology Division progress report, October 1, 1993--September 30, 1995

    SciTech Connect

    1995-10-01

    This Progress Report summarizes the research endeavors of the Biology Division of the Oak Ridge National Laboratory during the period October 1, 1993, through September 30, 1995. The report is structured to provide descriptions of current activities and accomplishments in each of the Division`s major organizational units. Lists of information to convey the entire scope of the Division`s activities are compiled at the end of the report. Attention is focused on the following research activities: molecular, cellular, and cancer biology; mammalian genetics and development; genome mapping program; and educational activities.

  1. [50 years anniversary of Research Institute for Occupational Medicine and Human Ecology with Siberian Division of RAMSc].

    PubMed

    Rukavishnikov, V S; Shaiakhmetov, S F; Gus'kova, T M

    2010-01-01

    The article covers main steps of establishment and development of Research Institute for Occupational medicine and Human ecology with Siberian Division of RAMSc over 50 years of activities, major results of research, contribution of the Institute personnel into development of hygienic science and practical medicine in Siberia.

  2. [Survey on scientific research activity in Spanish neonatal divisions between 2000 and 2004].

    PubMed

    Vento Torres, M; Villamor, E; Villamar, E; Botet, F; González de Dios, J; García-Muñoz, F; Sáenz de Pipaón, M

    2007-10-01

    Research is an essential activity in neonatology. Following the recommendation of the Spanish Neonatal Society (SEN), a questionnaire on the state of research activity was sent to all Spanish neonatal divisions belonging to all public and private institutions with structured neonatal activity. The following items were included: (i) clinical level of the units; (ii) academic degrees and professional qualifications of the staff members; (iii) characteristics of the scientific activity performed, and (iv) financial and technical aid supporting research. Of a total of 115 eligible hospitals, 86 hospitals (74.8 %), including most of the referral centers, participated in the survey. Notable among the positive results were the findings that a significant number of neonatologists have doctoral degrees (17.4 %), are active members of the SEN (74.9 %), and wish to participate in scientific research (100 %). In addition, the presence of epidemiologists (100 %), research support units (85 %) and ethical committees (93 %) in the hospitals is widespread. Negative aspects include the lack of a specific budget to initiate research (74 %), lack of protected time even with research grants (86 %), and lack of interrelation with other groups of basic or clinical researchers (43 %). Analysis of scientific production revealed that most of the abstracts presented are restricted to Spanish national meetings, and only a small number of consolidated groups publish regularly in peer-reviewed international journals with impact factor. Measures that could help to improve the current situation are the formation of multi-hospital groups, participation in comprehensive databases (SEN 1500), and joint meetings for basic and clinical scientists, among others. The results of this survey were presented at the Congress of Perinatal Medicine held in Las Palmas (November, 2005).

  3. Quarterly progress report for the Chemical and Energy Research Section of the Chemical Technology Division: January-March 1999

    SciTech Connect

    Jubin, R.T.

    1999-11-01

    This reports summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during the period January--March 1999. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within eight major areas of research: Hot Cell Operations, Process Chemistry and Thermodynamics, Molten Salt Reactor Experiment (MSRE) Remediation Studies, Chemistry Research, Separations and Materials Synthesis, Fluid Structure and Properties, Biotechnology Research, and Molecular Studies. The name of a technical contact is included with each task described, and readers are encouraged to contact these individuals if they need additional information. Activities conducted within the area of Hot Cell Operations included column loading of cesium from Melton Valley Storage Tank supematants using an engineered form of crystalline silicotitanate. A second task was to design and construct a continuously stirred tank reactor system to test the Savannah River-developed process of small-tank tetraphenylborate precipitation to remove cesium, strontium, and transuranics from supematant. Within the area of Process Chemistry and Thermodynamics, the problem of solids formation in process solutions from caustic treatment of Hanford sludge was addressed, including issues such as pipeline plugging and viscosity measurements. Investigation of solution conditions required to dissolve Hanford saltcake was also continued. MSRE Remediation Studies focused on recovery of {sup 233}U and its transformation into a stable oxide and radiolysis experiments to permit remediation of MSRE fuel salt. In the area of Chemistry Research, activities included studies relative to molecular imprinting for

  4. Subsequent dental research output of South African division of the IADR Colgate Prize entrants.

    PubMed

    Porter, Michelle I; McAlpine, Alistair J; Mkhaliphi, Diana S; Grossman, Elly S

    2005-11-01

    This study recorded the research output of all participants for the IADR (South African Division; SA) Colgate Prize for 1967-2004 to establish whether, in their later careers, prize winners had a greater research output than runners-up. Using a list of all entrants, each individual was classified as winner or runner-up and by gender, race, and research field of presentation. The publication output for each individual was obtained from PubMed. A Poisson regression set at P < 0.05 compared publication numbers between winners and runners-up. There were two groups of entrants: 101 participated once, and twenty-two participated twice or thrice. Winners had significantly more publications than runners-up, more so for the multiple entrants (winners 27.5+/-22.4; runners-up 16.5+/-25.5) than single entrants (winners 16.0+/-40.8; runners-up 12.0+/-27.7). The number of individuals participating in the Colgate Prize has declined, but representivity for race and gender is improving. This is the first study to establish that SA IADR Colgate Prize participants fulfil the long-term IADR ideal of research promotion among young investigators.

  5. University Libraries and Other General Research Libraries Section. General Research Libraries Division. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on university and other research libraries, presented at the 1983 International Federation of Library Associations (IFLA) conference, include: (1) "The Impact of Technology on Users of Academic and Research Libraries," in which C. Lee Jones (United States) focuses on the impact of technical advances in computing and…

  6. University Libraries and Other General Research Libraries Section. General Research Libraries Division. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on university and other research libraries, presented at the 1983 International Federation of Library Associations (IFLA) conference, include: (1) "The Impact of Technology on Users of Academic and Research Libraries," in which C. Lee Jones (United States) focuses on the impact of technical advances in computing and…

  7. IFLA General Conference, 1986. Education and Research Division. Round Table: Research in Reading. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    Papers presented at a roundtable session at the 1986 International Federation of Library Associations (IFLA) conference consider current research in reading. They include: (1) "Bibliopsychology--The Contribution of a Study of Temperament" (R. O. Linden, Japan), which examines research on the impact of communication media on the…

  8. Quarterly Progress Report for the Chemical and Energy Research Section of the Chemical Technology Division: July-September 1999

    SciTech Connect

    Jubin, R.T.

    2001-04-16

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during the period July-September 1999. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within ten major areas of research: Hot Cell Operations, Process Chemistry, Molten Salt Reactor Experiment (MSRE) Remediation Studies, Chemistry Research, Physical Properties Research, Biochemical Engineering, Separations and Materials Synthesis, Fluid Structures and Properties, Biotechnology Research, and Molecular Studies. The name of a technical contact is included with each task described, and readers are encouraged to contact these individuals if they need additional information. Activities conducted within the area of the Cell Operations involved the testing of two continuously stirred tank reactors in series to evaluate the Savannah River-developed process of small-tank tetraphenylborate precipitation to remove cesium, strontium and transuranics from supernatant. Within the area of Process Chemistry, various topics related to solids formation in process solutions from caustic treatment of Hanford sludge were addressed. Saltcake dissolution efforts continued, including the development of a predictive algorithm. New initiatives for the section included modeling activities centered on detection of hydrogen in {sup 233}U storage wells and wax formation in petroleum mixtures, as well as support for the Spallation Neutron Source (investigation of transmutation products formed during operation). Other activities involved in situ grouting and evaluation of options for use (i.e., as castable shapes) of depleted uranium. In a continuation of activities of the preceding

  9. Molecular basis for the reproductive division of labour in a lower termite

    PubMed Central

    Weil, Tobias; Rehli, Michael; Korb, Judith

    2007-01-01

    Background Polyphenism, the expression of different phenotypes with the same genetic background, is well known for social insects. The substantial physiological and morphological differences among the castes generally are the result of differential gene expression. In lower termites, workers are developmentally flexible to become neotenic replacement reproductives via a single moult after the death of the founding reproductives. Thus, both castes (neotenics and workers) are expected to differ mainly in the expression of genes linked to reproductive division of labour, which constitutes the fundamental basis of insect societies. Results Representational difference analysis of cDNAs was used to study differential gene expression between neotenics and workers in the drywood termite Cryptotermes secundus (Kalotermitidae). We identified and, at least partially cloned five novel genes that were highly expressed in female neotenics. Quantitative real-time PCR analysis of all five genes in different castes (neotenics, founding reproductives, winged sexuals and workers of both sexes) confirmed the differential expression patterns. In addition, the relative expression of these genes was determined in three body parts of female neotenics (head, thorax, and abdomen) using quantitative real-time PCR. Conclusion The identified genes could be involved in the control and regulation of reproductive division of labour. Interestingly, this study revealed an expression pattern partly similar to social Hymenoptera indicating both common and species-specific regulatory mechanisms in hemimetabolous and holometabolous social insects. PMID:17598892

  10. 1998 Chemical Technology Division Annual Technical Report.

    SciTech Connect

    Ackerman, J.P.; Einziger, R.E.; Gay, E.C.; Green, D.W.; Miller, J.F.

    1999-08-06

    The Chemical Technology (CMT) Division is a diverse technical organization with principal emphases in environmental management and development of advanced energy sources. The Division conducts research and development in three general areas: (1) development of advanced power sources for stationary and transportation applications and for consumer electronics, (2) management of high-level and low-level nuclear wastes and hazardous wastes, and (3) electrometallurgical treatment of spent nuclear fuel. The Division also performs basic research in catalytic chemistry involving molecular energy resources, mechanisms of ion transport in lithium battery electrolytes, and the chemistry of technology-relevant materials. In addition, the Division operates the Analytical Chemistry Laboratory, which conducts research in analytical chemistry and provides analytical services for programs at Argonne National Laboratory (ANL) and other organizations. Technical highlights of the Division's activities during 1998 are presented.

  11. National Research Program of the Water Resources Division, U.S. Geological Survey: Fiscal Year 1988

    USGS Publications Warehouse

    Friedman, Linda C.; Donato, Christine N.

    1989-01-01

    The National Research Program (NRP) of the US Geological Survey 's Water Resources Division (WRD) had its beginnings in the late 1950 's when ' core research ' was added as a line item to the Congressional budget. Since that time, the NRP has grown to encompass a broad spectrum of scientific investigations. The sciences of hydrology, mathematics, chemistry, physics, ecology, biology, geology, and engineering are used to gain a fundamental understanding of the processes that affect the availability, movement, and quality of the Nation 's water resources. The NRP is located principally in Reston, VA, Denver, CO, and Menlo Park , CA. The NRP is subdivided into six disciplines as follows: (1) Ecology; (2) Geomorphology and Sediment Transport; (3) Groundwater Chemistry; (4) Groundwater Hydrology; (5) Surface Water Chemistry; and (6) Surface Water Hydrology. The report provides current information about the NRP on an annual basis. Organized by the six research disciplines, the volume contains a summary of the problem, objective, approach, and progress for each project that was active during fiscal year 1988.

  12. Library Theory and Research Section. Round Table on Library History. Education and Research Division. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on theory and research in library history presented at the 1982 International Federation of Library Associations (IFLA) conference include: (1) "The Future of the Library's Past: Library Administrative Records Preservation, Policy and Practice," a discussion by Paul Sturges (United Kingdom) of the need for library records…

  13. The NIAID Division of AIDS enterprise information system: integrated decision support for global clinical research programs.

    PubMed

    Kagan, Jonathan M; Gupta, Nitin; Varghese, Suresh; Virkar, Hemant

    2011-12-01

    The National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS (DAIDS) Enterprise Information System (DAIDS-ES) is a web-based system that supports NIAID in the scientific, strategic, and tactical management of its global clinical research programs for HIV/AIDS vaccines, prevention, and therapeutics. Different from most commercial clinical trials information systems, which are typically protocol-driven, the DAIDS-ES was built to exchange information with those types of systems and integrate it in ways that help scientific program directors lead the research effort and keep pace with the complex and ever-changing global HIV/AIDS pandemic. Whereas commercially available clinical trials support systems are not usually disease-focused, DAIDS-ES was specifically designed to capture and incorporate unique scientific, demographic, and logistical aspects of HIV/AIDS treatment, prevention, and vaccine research in order to provide a rich source of information to guide informed decision-making. Sharing data across its internal components and with external systems, using defined vocabularies, open standards and flexible interfaces, the DAIDS-ES enables NIAID, its global collaborators and stakeholders, access to timely, quality information about NIAID-supported clinical trials which is utilized to: (1) analyze the research portfolio, assess capacity, identify opportunities, and avoid redundancies; (2) help support study safety, quality, ethics, and regulatory compliance; (3) conduct evidence-based policy analysis and business process re-engineering for improved efficiency. This report summarizes how the DAIDS-ES was conceptualized, how it differs from typical clinical trial support systems, the rationale for key design choices, and examples of how it is being used to advance the efficiency and effectiveness of NIAID's HIV/AIDS clinical research programs.

  14. An Update on the NASA Planetary Science Division Research and Analysis Program

    NASA Astrophysics Data System (ADS)

    Bernstein, Max; Richey, Christina; Rall, Jonathan

    2015-11-01

    Introduction: NASA’s Planetary Science Division (PSD) solicits its research and analysis (R&A) programs each year in Research Opportunities in Space and Earth Sciences (ROSES). Beginning with the 2014 ROSES solicitation, PSD changed the structure of the program elements under which the majority of planetary science R&A is done. Major changes included the creation of five core research program elements aligned with PSD’s strategic science questions, the introduction of several new R&A opportunities, new submission requirements, and a new timeline for proposal submission.ROSES and NSPIRES: ROSES contains the research announcements for all of SMD. Submission of ROSES proposals is done electronically via NSPIRES: http://nspires.nasaprs.com. We will present further details on the proposal submission process to help guide younger scientists. Statistical trends, including the average award size within the PSD programs, selections rates, and lessons learned, will be presented. Information on new programs will also be presented, if available.Review Process and Volunteering: The SARA website (http://sara.nasa.gov) contains information on all ROSES solicitations. There is an email address (SARA@nasa.gov) for inquiries and an area for volunteer reviewers to sign up. The peer review process is based on Scientific/Technical Merit, Relevance, and Level of Effort, and will be detailed within this presentation.ROSES 2015 submission changes: All PSD programs will continue to use a two-step proposal submission process. A Step-1 proposal is required and must be submitted electronically by the Step-1 due date. The Step-1 proposal should include a description of the science goals and objectives to be addressed by the proposal, a brief description of the methodology to be used to address the science goals and objectives, and the relevance of the proposed research to the call submitted to.

  15. Visualization Gallery from the Computational Research Division at Lawrence Berkeley National Laboratory

    DOE Data Explorer

    This excellent collection of visualization vignettes highlights research work done by the LBNL/NERSC Visualization Group and its collaborators from 1993 to the present. Images lead to technical explanations and project details, helping users to branch out to other related sources. Titles of the projects provide clues both to the imaging focus of the research and the scientific discipline for which the visualizations are intended. Only a few of the many titles/images/projects are listed here: 1) Hybrid Parallelism for Volume Rendering at Large Scale Analysis of Laser Wakefield Particle Acceleration Data; 2) Visualization of Microearthquake Data from Enhanced Geothermal Systems; 3) PointCloudXplore: Visualization and Analysis of 3D Gene Expression Data; 4) Visualization of Quantum Monte-Carlo simulations; 5) Global Cloud Resolving Models; 6) Visualization of large-scale GFDL/NOAA climate simulations; 7) Direct Numerical Simulation of Turbulent Flame Quenching by Fine Water Droplets; 8) Visualization of Magneto-rotational instability and turbulent angular momentum transport; 9) Sunfall: Visual Analytics for Astrophysics; 10) Fast Contour Descriptor Algorithm for Supernova Image Classification; 11) Supernova Recognition Using Support Vector Machines; 12) High Performance Visualization - Query-Driven Network Traffic Analysis; 13) Visualization of Magneto-rotational instability and turbulent angular momentum transport; 14) Life Sciences: Cell Division of Caulobacter Crescentus; 15) Electron Cloud Simulations.

  16. Physics Education Research at the Upper Division at the University of Maine

    NASA Astrophysics Data System (ADS)

    Thompson, John

    2013-04-01

    Researchers from the University of Maine Physics Education Research Laboratory are conducting several investigations of the learning and teaching of physics beyond the introductory level. Content topics include intermediate mechanics, electronics, thermodynamics and statistical mechanics. One focus of our work is the identification and addressing of specific student difficulties with topics such as damped harmonic motion, bipolar junction transistor (BJT) circuits, work, entropy, and the Boltzmann factor. Student understanding and use of the underlying mathematics has been one important emerging theme, including definite integrals, partial derivatives, and linear differential equations. Recent work in mechanics has focused on understanding the interplay of mathematical and physical reasoning when describing damped harmonic motion, including framing and representational issues. In electronics, there has been an ongoing investigation of student understanding of the behavior of basic BJT follower and amplifier circuits as well as related issues of signal and bias. In thermal physics, student understanding of state functions, heat engines and the Carnot cycle, the First and Second Laws of thermodynamics, and the macroscopic and microscopic perspectives on entropy have been investigated. The greater content sophistication in these courses has drawn attention to the specific needs, constraints, and advantages of instructional materials tailored to the upper division. Future directions include more attention to interdisciplinary topics across mathematics, physics, and engineering in particular, as well as metacognition in the laboratory.

  17. Environmental effects research. Environmental Research Division annual report, January-December 1983. Part 3

    SciTech Connect

    Not Available

    1984-12-01

    The Terrestrial Ecology group continued its involvement in the National Crop Loss Assessment Network, and studies of O/sub 3/ effects on winter wheat and soybeans were completed. Experiments on O/sub 3/ x SO/sub 2/ interactions on soybeans were also performed. The Microcosms for Acid Rain Studies (MARS) project had its first full year of research and much information concerning acid rain impacts on soil-plant systems was collected. A study of the influence of temporal variations in rain acidity on soybean productivity was also initiated. The aquatic radiochemistry group continued measurements of the mobility of plutonium and americium at a disposal site at Los Alamos and initiated similar work at Hanford. Laboratory tracer experiments were carried out to study the adsorptive behavior of neptunium, the solubility limits of plutonium, and the influence of rare earth concentration on the sorption and redox behavior of plutonium. The soil-plant process group initiated several studies on the influence of mycorrhizae to host plants in disturbed and natural environments. Much of the past research has been concerned with understanding mycorrhizal fungi propagule dynamics as related to disturbances associated with energy extraction. Future research will be directed at understanding how below-ground symbiotic associations may increase the fitness of host plants. Emphasis is being placed on resource acquisition and compartmental strategies. Separate analytics have been indexed for EDB.

  18. Performance Data Report: Space Medicine Division, Human Research Program, Behavioural Health and Performance Research Element

    NASA Technical Reports Server (NTRS)

    Shea, Camille; Keeton, Kathryn E.; Schmidt, Lacey L.; Slack, Kelley J.; Patterson, Holly N.; Leveton, Lauren B.; Holland, Albert W.

    2012-01-01

    This report is the result of a collaborative effort between NASA?s Behavioral Health & Performance (BHP) Research and Operations Group to investigate and determine the availability of data pertaining to behavioral performance (and other pertinent variables) that have been collected by the laboratories at NASA?s Johnson Space Center. BHP?s Operations and Research groups collaborated to systematically identify what types of performance data are needed in relevant BHP performance domains and also to conduct structured interviews with NASA personnel to identify which data do or do not exist currently (and for instances where such data exist, to evaluate the type, quality, accessibility, and confidentiality of those data). The authors defined outcome categories of performance that encapsulate BHP performance domains, mapped BHP Research Risks and Gaps onto those performance outcome categories, and identified and prioritized indicators for each outcome category. The team identified key points of contact (subject matter experts [SMEs]) as potential interviewees, created a template for structured interview questions about sources and accessibility of performance data, and coordinated and conducted structured interviews with the SMEs. The methodology, results, and implications of this effort, as well as forward work needed, are discussed in this report.

  19. Environmental Assessment for Air Force Research Laboratory Space Vehicles Integrated Experiments Division Office Space at Kirtland Air Force Base, Albuquerque, New Mexico

    DTIC Science & Technology

    2005-06-01

    AIR FORCE RESEARCH LABORATORY SPACE VEHICLES INTEGRATED EXPERMENTS DIVISION OFFICE SPACE AT KIRTLAND AIR FORCE ... Kirtland Air Force Base (KAFB). The office building would house the Air Force Research Laboratory Space Vehicles Integrated Experiments Division...ADDRESS(ES) Air Force Research Laboratory ,Space Vehicles Directorate,3550 Aberdeen Ave. SE, Kirtland

  20. Molecular biology research in neuropsychiatry: India's contribution.

    PubMed

    Sathyanarayana Rao, T S; Ramesh, B N; Vasudevaraju, P; Rao, K S J

    2010-01-01

    Neuropsychiatric disorders represent the second largest cause of morbidity worldwide. These disorders have complex etiology and patho-physiology. The major lacunae in the biology of the psychiatric disorders include genomics, biomarkers and drug discovery, for the early detection of the disease, and have great application in the clinical management of disease. Indian psychiatrists and scientists played a significant role in filling the gaps. The present annotation provides in depth information related to research contributions on the molecular biology research in neuropsychiatric disorders in India. There is a great need for further research in this direction as to understand the genetic association of the neuropsychiatric disorders; molecular biology has a tremendous role to play. The alterations in gene expression are implicated in the pathogenesis of several neuropsychiatric disorders, including drug addiction and depression. The development of transgenic neuropsychiatric animal models is of great thrust areas. No studies from India in this direction. Biomarkers in neuropsychiatric disorders are of great help to the clinicians for the early diagnosis of the disorders. The studies related to gene-environment interactions, DNA instability, oxidative stress are less studied in neuropsychiatric disorders and making efforts in this direction will lead to pioneers in these areas of research in India. In conclusion, we provided an insight for future research direction in molecular understanding of neuropsychiatry disorders.

  1. Report style guide for subcontractors of the Efficiency and Renewables Research Section, Energy Division, Oak Ridge National Laboratory

    SciTech Connect

    Stone, T.A.; Bennett, M.N.

    1992-09-01

    This document has been paraphrased from the ORNL Document Preparation Guide (DPG). It is intended for use by Efficiency and Renewables Research Section, Energy Division, ORNL subcontractor reports so that review and editing effort can be minimized. Topics covered are typing instructions, document format, usage, abbreviations and acronyms, and standard editing marks.

  2. Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division.

    PubMed

    Samson, Rachel Y; Obita, Takayuki; Hodgson, Ben; Shaw, Michael K; Chong, Parkson Lee-Gau; Williams, Roger L; Bell, Stephen D

    2011-01-21

    Members of the crenarchaeal kingdom, such as Sulfolobus, divide by binary fission yet lack genes for the otherwise near-ubiquitous tubulin and actin superfamilies of cytoskeletal proteins. Recent work has established that Sulfolobus homologs of the eukaryotic ESCRT-III and Vps4 components of the ESCRT machinery play an important role in Sulfolobus cell division. In eukaryotes, several pathways recruit ESCRT-III proteins to their sites of action. However, the positioning determinants for archaeal ESCRT-III are not known. Here, we identify a protein, CdvA, that is responsible for recruiting Sulfolobus ESCRT-III to membranes. Overexpression of the isolated ESCRT-III domain that interacts with CdvA results in the generation of nucleoid-free cells. Furthermore, CdvA and ESCRT-III synergize to deform archaeal membranes in vitro. The structure of the CdvA/ESCRT-III interface gives insight into the evolution of the more complex and modular eukaryotic ESCRT complex.

  3. Using a Research-based Approach to Transform Upper-division Laboratory Courses

    NASA Astrophysics Data System (ADS)

    Lewandowski, Heather

    2013-04-01

    Preparing undergraduate physics majors for future careers in experimental science is one of the main goals of our current physics education system. Upper-division lab courses and undergraduate research experiences are the natural places where this training can take place. At the University of Colorado Boulder, traditional and PER faculty have been working together to comprehensively transform our Advanced Lab course and evaluate the impacts of these changes. I will discuss our two-year effort to establish learning goals, transform the course, and measure the impact of the transformation on students' scientific process skills. As part of this effort, we developed a validated survey (E-CLASS) to assess students' attitudes and beliefs about experimental physics. This online survey is available to instructors at any institution whom would like to learn more about the impact of their lab courses at all levels on students' attitudes about experimental physics. The survey is designed to give instructors actionable feedback to help them improve their courses.

  4. Coordinating Center: Molecular and Cellular Findings of Screen-Detected Lesions | Division of Cancer Prevention

    Cancer.gov

    DESCRIPTION (provided by applicant): The Molecular and Cellular Characterization of Screen‐Detected Lesions ‐ Coordinating Center and Data Management Group will provide support for the participating studies responding to RFA CA14‐10. The coordinating center supports three main domains: network coordination, statistical support and computational analysis and protocol development and database support. Support for communication is provided through an interactive web portal, management of conference calls, and meeting support. |

  5. An Update on the NASA Planetary Science Division Research and Analysis Program

    NASA Astrophysics Data System (ADS)

    Richey, Christina; Bernstein, Max; Rall, Jonathan

    2015-01-01

    Introduction: NASA's Planetary Science Division (PSD) solicits its Research and Analysis (R&A) programs each year in Research Opportunities in Space and Earth Sciences (ROSES). Beginning with the 2014 ROSES solicitation, PSD will be changing the structure of the program elements under which the majority of planetary science R&A is done. Major changes include the creation of five core research program elements aligned with PSD's strategic science questions, the introduction of several new R&A opportunities, new submission requirements, and a new timeline for proposal submissionROSES and NSPIRES: ROSES contains the research announcements for all of SMD. Submission of ROSES proposals is done electronically via NSPIRES: http://nspires.nasaprs.com. We will present further details on the proposal submission process to help guide younger scientists. Statistical trends, including the average award size within the PSD programs, selections rates, and lessons learned, will be presented. Information on new programs will also be presented, if available.Review Process and Volunteering: The SARA website (http://sara.nasa.gov) contains information on all ROSES solicitations. There is an email address (SARA@nasa.gov) for inquiries and an area for volunteer reviewers to sign up. The peer review process is based on Scientific/Technical Merit, Relevance, and Level of Effort, and will be detailed within this presentation.ROSES 2014 submission changes: All PSD programs will use a two-step proposal submission process. A Step-1 proposal is required and must be submitted electronically by the Step-1 due date. The Step-1 proposal should include a description of the science goals and objectives to be addressed by the proposal, a brief description of the methodology to be used to address the science goals and objectives, and the relevance of the proposed research to the call submitted to.Additional Information: Additional details will be provided on the Cassini Data Analysis Program, the

  6. Progress Report for the Chemical and Energy Research Section of the Chemical Technology Division: July-December 1998

    SciTech Connect

    Jubin, R.T.

    1999-06-01

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during the period July-December 1998. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications.

  7. Job Opening for Medical Officer in DCP’s Breast and Gynecologic Cancer Research Group | Division of Cancer Prevention

    Cancer.gov

    The Breast and Gynecologic Cancer Research Group (BGCRG), Division of Cancer Prevention (DCP), National Cancer Institute (NCI), has an opening for an experienced Medical Officer. BGCRG focuses on fostering the development and conduct of research on the prevention and early detection of breast cancer, cervix and human papillomavirus (HPV)-related cancers, endometrial cancers, ovarian cancers, and precursor conditions related to these cancers. Learn more about BGCRG. |

  8. Structural dynamics division research and technology accomplishments for fiscal year 1990 and plans for fiscal year 1991

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1991-01-01

    The research accomplishments of the Structural Dynamics Division for F.Y. 1991 are presented. The work is discussed in terms of highlights of accomplishments during the past year and plans for the current year as they relate to 5-year plans and the objectives of each technical area. Included is research on unsteady aerodynamics, helicopter rotors, computational fluid dynamics, oscillations of leading edge flaps of a delta wing, and aircraft wing loads.

  9. Quarterly Progress Report for the Chemical and Energy Research Section of the Chemical Technology Division: April-June 1998

    SciTech Connect

    Jubin, R.T.

    1999-04-01

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division at Oak Ridge National Laboratory (ORNL) during th eperiod April-June 1998. The section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications.

  10. Molecular Science Research Center 1992 annual report

    SciTech Connect

    Knotek, M.L.

    1994-01-01

    The Molecular Science Research Center is a designated national user facility, available to scientists from universities, industry, and other national laboratories. After an opening section, which includes conferences hosted, appointments, and projects, this document presents progress in the following fields: chemical structure and dynamics; environmental dynamics and simulation; macromolecular structure and dynamics; materials and interfaces; theory, modeling, and simulation; and computing and information sciences. Appendices are included: MSRC staff and associates, 1992 publications and presentations, activities, and acronyms and abbreviations.

  11. Genetic and molecular ecotoxicology: a research framework.

    PubMed

    Anderson, S; Sadinski, W; Shugart, L; Brussard, P; Depledge, M; Ford, T; Hose, J; Stegeman, J; Suk, W; Wirgin, I

    1994-12-01

    Participants at the Napa Conference on Genetic and Molecular Ecotoxicology assessed the status of this field in light of heightened concerns about the genetic effects of exposure to hazardous substances and recent advancements in our capabilities to measure those effects. We present here a synthesis of the ideas discussed throughout the conference, including definitions of important concepts in the field and critical research needs and opportunities. While there were many opinions expressed on these topics, there was general agreement that there are substantive new opportunities to improve the impact of genetic and molecular ecotoxicology on prediction of sublethal effects of exposure to hazardous substances. Future studies should emphasize integration of genetic ecotoxicology, ecological genetics, and molecular biology and should be directed toward improving our understanding of the ecological implications of genotoxic responses. Ecological implications may be assessed at either the population or ecosystem level; however, a population-level focus may be most pragmatic. Recent technical advancements in measuring genetic and molecular responses to toxicant exposure will spur rapid progress. These new techniques have considerable promise for increasing our understanding of both mechanisms of toxicity on genes or gene products and the relevance of detrimental effects to individual fitness.

  12. Biology and Medicine Division: Annual report 1986

    SciTech Connect

    Not Available

    1987-04-01

    The Biology and Medicine Division continues to make important contributions in scientific areas in which it has a long-established leadership role. For 50 years the Division has pioneered in the application of radioisotopes and charged particles to biology and medicine. There is a growing emphasis on cellular and molecular applications in the work of all the Division's research groups. The powerful tools of genetic engineering, the use of recombinant products, the analytical application of DNA probes, and the use of restriction fragment length polymorphic DNA are described and proposed for increasing use in the future.

  13. Accelerator and Fusion Research Division annual report, October 1980-September 1981. Fiscal year, 1981

    SciTech Connect

    Johnson, R.K.; Thomson, H.A.

    1982-04-01

    Major accomplishments during fiscal year 1981 are presented. During the Laboratory's 50th anniversary celebrations, AFRD and the Nuclear Science Division formally dedicated the new (third) SuperHILAC injector that adds ions as heavy as uranium to the ion repertoire at LBL's national accelerator facilities. The Bevalac's new multiparticle detectors (the Heavy Ion Spectrometer System and the GSI-LBL Plastic Ball/Plastic Wall) were completed in time to take data before the mid-year shutdown to install the new vacuum liner, which passed a milestone in-place test with flying colors in September. The Bevalac biomedical program continued patient treatment with neon beams aimed at establishing a complete data base for a dedicated biomedical accelerator, the design of which NCI funded during the year. Our program to develop alternative Isabelle superconducting dipole magnets, which DOE initiated in FY80, proved the worth of a new magnet construction technique and set a world record - 7.6 Tesla at 1.8 K - with a model magnet in our upgraded test facility. Final test results at LBL were obtained by the Magnetic Fusion Energy Group on the powerful neutral beam injectors developed for Princeton's TFTR. The devices exceeded the original design requirements, thereby completing the six-year, multi-million-dollar NBSTF effort. The group also demonstrated the feasibility of efficient negative-ion-based neutral beam plasma heating for the future by generating 1 A of negative ions at 34 kV for 7 seconds using a newly developed source. Collaborations with other research centers continued, including: (1) the design of LBL/Exxon-dedicated beam lines for the Stanford Synchrotron Radiation Laboratory; (2) beam cooling tests at Fermilab and the design of a beam cooling system for a proton-antiproton facility there; and (3) the development of a high-current betatron for possible application to a free electron laser.

  14. Occupational health, waste management, and environmental research program of the Health Division 1981. Progress report

    SciTech Connect

    Voelz, G.L.

    1983-09-01

    The primary responsibility of the Health Division at the Los Alamos National Laboratory is to provide effective programs in health, safety, waste processing, and environmental protection for the Laboratory. During 1981, evaluations of respiratory protective equipment included 3 special DOE contractor supplied-air suits or hoods and 10 commercial supplied-air devices. Preliminary results of chemical permeation tests of different protective garment materials are reported. Industrial hygiene field studies of oil shale work were conducted at the Geokinetics true in situ facility and the Rio Blanco modified in situ facility. An occupational medical survey of workers at the Geokinetics, Inc., facility was completed. Research on the generation and characterization of aerosols was continued for inhalation studies of man-made mineral fibers and oil shale aerosols. The distribution of /sup 241/Am in a whole body was determined by tissue analyses. Preliminary results of mortality in workers formerly employed at the Rocky Flats plant were reported. A simplified method for the analysis of plutonium in urine has been developed. Instrumentation development resulted in a portable computer system for field data analysis and a small, computerized, wristwatch-style radiation dosimeter. Environmental surveillance at Los Alamos during 1981 showed the highest estimated radiation dose due to Laboratory operations is about 4% of the dose due to the natural radioactivity here. A study was completed on alternative strategies for long-term management of Los Alamos transuranic wastes. A successful 10-day test burn of pentachlorophenol-contaminated wastes was conducted in the Controlled Air Incinerator. Decontamination factors for five fission products in the off-gas handling system of the incinerator were measured.

  15. Molecular Science Research Center, 1991 annual report

    SciTech Connect

    Knotek, M.L.

    1992-03-01

    During 1991, the Molecular Science Research Center (MSRC) experienced solid growth and accomplishment and the Environmental, and Molecular Sciences Laboratory (EMSL) construction project moved forward. We began with strong programs in chemical structure and dynamics and theory, modeling, and simulation, and both these programs continued to thrive. We also made significant advances in the development of programs in materials and interfaces and macromolecular structure and dynamics, largely as a result of the key staff recruited to lead these efforts. If there was one pervasive activity for the past year, however, it was to strengthen the role of the EMSL in the overall environmental restoration and waste management (ER/WM) mission at Hanford. These extended activities involved not only MSRC and EMSL staff but all PNL scientific and technical staff engaged in ER/WM programs.

  16. Argonne National Laboratory, High Energy Physics Division: Semiannual report of research activities, July 1, 1986-December 31, 1986

    SciTech Connect

    Not Available

    1987-01-01

    This paper discusses the research activity of the High Energy Physics Division at the Argonne National Laboratory for the period, July 1986-December 1986. Some of the topics included in this report are: high resolution spectrometers, computational physics, spin physics, string theories, lattice gauge theory, proton decay, symmetry breaking, heavy flavor production, massive lepton pair production, collider physics, field theories, proton sources, and facility development. (LSP)

  17. IFLA General Conference, 1989. Division of General Research Libraries. Section of National Libraries; Section of University Libraries and Other General Research Libraries; Section of Parliamentary Libraries. Booklet 10.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    There are 11 papers from the Division of General Research Libraries in this compilation: (1) "National Library and Information Needs: Alternative Ways of Meeting Them, with Special Reference to the Role of National Libraries" (Maurice B. Line); (2) "Managing Change in National LIbraries: The Library of Congress" (James H.…

  18. IFLA General Conference, 1991. Division of General Research Libraries: Section of National Libraries; Section of University Libraries and Other General Research Libraries; Section of Parliamentary Libraries. Booklet 1.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    The 11 papers in this booklet were presented at meetings of 3 sections within the Division of General Research Libraries: (1) "On the Concept of Development of the National Library of the USSR" (N. I. Tyulina); (2) "Strategic Planning in National Libraries" (Maurice B. Line, UK); (3) "Strategic Planning in National…

  19. IFLA General Conference, 1992. Division of General Research Libraries: Section on National Libraries; Section on Parliamentary Libraries; Section on University Libraries and Other General Research Libraries. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, London (England).

    Fifteen papers delivered for the Division of General Research Libraries at the 1992 International Federation of Library Associations and Institutions annual meeting are presented. These papers deal with national libraries, parliamentary (legislative) libraries, and university libraries. The papers are: (1) "Seeking Alternatives to National…

  20. Quarterly progress report for the Chemical and Energy Research Section of the Chemical Technology Division: January--March 1997

    SciTech Connect

    Jubin, R.T.

    1998-01-01

    This report summarizes the major activities conducted in the Chemical and Energy Research Section of the Chemical Technology Division (CTD) at Oak Ridge National Laboratory (ORNL) during the period January--March 1997. Created in March 1997 when the CTD Chemical Development and Energy Research sections were combined, the Chemical and Energy Research Section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within seven major areas of research: Hot Cell Operations, Process Chemistry and Thermodynamics, Molten Salt Reactor Experiment (MSRE) Remediation Studies, Chemistry Research, Separations and Materials Synthesis, Solution Thermodynamics, and Biotechnology Research. The name of a technical contact is included with each task described in the report, and readers are encouraged to contact these individuals if they need additional information.

  1. Molecular Science Research Center annual report

    SciTech Connect

    Knotek, M.L.

    1991-01-01

    The Chemical Structure and Dynamics group is studying chemical kinetics and reactions dynamics of terrestrial and atmospheric processes as well as the chemistry of complex waste forms and waste storage media. Staff are using new laser systems and surface-mapping techniques in combination with molecular clusters that mimic adsorbate/surface interactions. The Macromolecular Structure and Dynamics group is determining biomolecular structure/function relationships for processes the control the biological transformation of contaminants and the health effects of toxic substances. The Materials and Interfaces program is generating information needed to design and synthesize advanced materials for the analysis and separation of mixed chemical waste, the long-term storage of concentrated hazardous materials, and the development of chemical sensors for environmental monitoring of various organic and inorganic species. The Theory, Modeling, and Simulation group is developing detailed molecular-level descriptions of the chemical, physical, and biological processes in natural and contaminated systems. Researchers are using the full spectrum of computational techniques. The Computer and Information Sciences group is developing new approaches to handle vast amounts of data and to perform calculations for complex natural systems. The EMSL will contain a high-performance computing facility, ancillary computing laboratories, and high-speed data acquisition systems for all major research instruments.

  2. The Use of Biospecimens in Population-Based Research: A Review of the National Cancer Institute's Division of Cancer Control and Population Sciences Grant Portfolio

    PubMed Central

    Mette, Eliza; Hoyle, Brittany; Rogers, Scott D.; Gillanders, Elizabeth M.; Schully, Sheri D.; Mechanic, Leah E.

    2014-01-01

    Over the past two decades, researchers have increasingly used human biospecimens to evaluate hypotheses related to disease risk, outcomes and treatment. We conducted an analysis of population-science cancer research grants funded by the National Cancer Institute (NCI) to gain a more comprehensive understanding of biospecimens and common derivatives involved in those studies and identify opportunities for advancing the field. Data available for 1,018 extramural, peer-reviewed grants (active as of July 2012) supported by the Division of Cancer Control and Population Sciences (DCCPS), the NCI Division that supports cancer control and population-science extramural research grants, were analyzed. 455 of the grants were determined to involve biospecimens or derivatives. The most common specimen types included were whole blood (51% of grants), serum or plasma (40%), tissue (39%), and the biospecimen derivative, DNA (66%). While use of biospecimens in molecular epidemiology has become common, biospecimens for behavioral and social research is emerging, as observed in our analysis. Additionally, we found the majority of grants were using already existing biospecimens (63%). Grants that involved use of existing biospecimens resulted in lower costs (studies that used existing serum/plasma biospecimens were 4.2 times less expensive) and more publications per year (1.4 times) than grants collecting new biospecimens. This analysis serves as a first step at understanding the types of biospecimen collections supported by NCI DCCPS. There is room to encourage increased use of archived biospecimens and new collections of rarer specimen and cancer types, as well as for behavioral and social research. To facilitate these efforts, we are working to better catalogue our funded resources and make that data available to the extramural community. PMID:25162460

  3. The use of biospecimens in population-based research: a review of the National Cancer Institute's Division of Cancer Control and Population Sciences grant portfolio.

    PubMed

    Carrick, Danielle M; Mette, Eliza; Hoyle, Brittany; Rogers, Scott D; Gillanders, Elizabeth M; Schully, Sheri D; Mechanic, Leah E

    2014-08-01

    Over the past two decades, researchers have increasingly used human biospecimens to evaluate hypotheses related to disease risk, outcomes and treatment. We conducted an analysis of population-science cancer research grants funded by the National Cancer Institute (NCI) to gain a more comprehensive understanding of biospecimens and common derivatives involved in those studies and identify opportunities for advancing the field. Data available for 1,018 extramural, peer-reviewed grants (active as of July 2012) supported by the Division of Cancer Control and Population Sciences (DCCPS), the NCI Division that supports cancer control and population-science extramural research grants, were analyzed. 455 of the grants were determined to involve biospecimens or derivatives. The most common specimen types included were whole blood (51% of grants), serum or plasma (40%), tissue (39%), and the biospecimen derivative, DNA (66%). While use of biospecimens in molecular epidemiology has become common, biospecimens for behavioral and social research is emerging, as observed in our analysis. Additionally, we found the majority of grants were using already existing biospecimens (63%). Grants that involved use of existing biospecimens resulted in lower costs (studies that used existing serum/plasma biospecimens were 4.2 times less expensive) and more publications per year (1.4 times) than grants collecting new biospecimens. This analysis serves as a first step at understanding the types of biospecimen collections supported by NCI DCCPS. There is room to encourage increased use of archived biospecimens and new collections of rarer specimen and cancer types, as well as for behavioral and social research. To facilitate these efforts, we are working to better catalogue our funded resources and make that data available to the extramural community.

  4. An Overview of Networked Simulation Technology from the Warfighter Training Research Division Perspective

    DTIC Science & Technology

    2003-07-01

    HEA Dives Into the HLA Pool: Tasmanian Devil Following the success of the Roadrunner 98 DIS based exercise, the division hoped to repeat its good...fortune with efforts named after Warner Brother’s cartoon characters. The Tasmanian Devil Project, also known as Taz, was a cooperative effort...goal of Tasmanian Devil was to develop and demonstrate two federations that utilized different aircraft training simulators but a common FOM to

  5. Mitochondrial fusion and division: Regulation and role in cell viability.

    PubMed

    Benard, Giovanni; Karbowski, Mariusz

    2009-05-01

    Discovery of various molecular components regulating dynamics and organization of the mitochondria in cells, together with novel insights into the role of mitochondrial fusion and division in the maintenance of cellular homeostasis, have provided some of the most exciting breakthroughs in the last decade of mitochondrial research. The focus of this review is on the regulation of mitochondrial fusion and division machineries. The newly identified factors associated with mitofusin/OPA1-dependent mitochondrial fusion, and Drp1-dependent mitochondrial division are discussed. Furthermore, the most recent findings on the role of mitochondrial fusion and division in the maintenance of cell function are also reviewed here in some detail.

  6. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)

    SciTech Connect

    Eisenberg, David S.

    2008-07-15

    The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission of the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages

  7. Chemical Technology Division annual technical report, 1996

    SciTech Connect

    1997-06-01

    CMT is a diverse technical organization with principal emphases in environmental management and development of advanced energy sources. It conducts R&D in 3 general areas: development of advanced power sources for stationary and transportation applications and for consumer electronics, management of high-level and low-level nuclear wastes and hazardous wastes, and electrometallurgical treatment of spent nuclear fuel. The Division also performs basic research in catalytic chemistry involving molecular energy resources, mechanisms of ion transport in lithium battery electrolytes, materials chemistry of electrified interfaces and molecular sieves, and the theory of materials properties. It also operates the Analytical Chemistry Laboratory, which conducts research in analytical chemistry and provides analytical services for programs at ANL and other organizations. Technical highlights of the Division`s activities during 1996 are presented.

  8. Structures Division

    NASA Technical Reports Server (NTRS)

    1997-01-01

    The NASA Lewis Research Center Structures Division is an international leader and pioneer in developing new structural analysis, life prediction, and failure analysis related to rotating machinery and more specifically to hot section components in air-breathing aircraft engines and spacecraft propulsion systems. The research consists of both deterministic and probabilistic methodology. Studies include, but are not limited to, high-cycle and low-cycle fatigue as well as material creep. Studies of structural failure are at both the micro- and macrolevels. Nondestructive evaluation methods related to structural reliability are developed, applied, and evaluated. Materials from which structural components are made, studied, and tested are monolithics and metal-matrix, polymer-matrix, and ceramic-matrix composites. Aeroelastic models are developed and used to determine the cyclic loading and life of fan and turbine blades. Life models are developed and tested for bearings, seals, and other mechanical components, such as magnetic suspensions. Results of these studies are published in NASA technical papers and reference publication as well as in technical society journal articles. The results of the work of the Structures Division and the bibliography of its publications for calendar year 1995 are presented.

  9. 2010 Plant Molecular Biology Gordon Research Conference

    SciTech Connect

    Michael Sussman

    2010-07-23

    The Plant Molecular Biology Conference has traditionally covered a breadth of exciting topics and the 2010 conference will continue in that tradition. Emerging concerns about food security have inspired a program with three main themes: (1) genomics, natural variation and breeding to understand adaptation and crop improvement, (2) hormonal cross talk, and (3) plant/microbe interactions. There are also sessions on epigenetics and proteomics/metabolomics. Thus this conference will bring together a range of disciplines, will foster the exchange of ideas and enable participants to learn of the latest developments and ideas in diverse areas of plant biology. The conference provides an excellent opportunity for individuals to discuss their research because additional speakers in each session will be selected from submitted abstracts. There will also be a poster session each day for a two-hour period prior to dinner. In particular, this conference plays a key role in enabling students and postdocs (the next generation of research leaders) to mingle with pioneers in multiple areas of plant science.

  10. Research on free-space optical communication based on time-division multiplexing

    NASA Astrophysics Data System (ADS)

    Wang, Dan; Zhou, Wenchao; Li, Zhen; Chen, Zhenqiang; Yin, Hao; Zhu, Siqi; Li, Anming

    2016-10-01

    This paper aims at designing and demonstrating a video and audio signals synchronous wireless transmission of free-space optical communication (FSO) system. Video and audio signals were modulated by the acousto-optical modulator (AOM). With the help of a designed circuit and programmable microcontroller, the system based on time division multiplexing (TDM) achieves the functions of signal de-multiplexing and wireless transmitting. Proved by experiments, the system meets the actual requirements with advantages of flexibility, practicality and low cost. And it provides an efficient scheme of synchronous wireless transmission of video and audio signals for monitoring system and TV access network.

  11. Health and Safety Research Division: Progress report, October 1, 1985-March 31, 1987

    SciTech Connect

    Walsh, P.J.

    1987-09-01

    This report summarizes the progress in our programs for the period October 1, 1985, through March 31, 1987. The division's presentations and publications represented important contributions on the forefronts of many fields. Eleven invention disclosures were filed, two patent applications submitted, and one patent issued. The company's transfers new technologies to the private sector more efficiently than in the past. The division's responsibilities to DOE under the Uranium Mill Tailings Remedial Action (UMTRA) program includes inclusion recommendations for 3100 properties. The nuclear medicine program developed new radiopharmaceuticals and radionuclide generators through clinical trials with some of our medical cooperatives. Two major collaborative indoor air quality studies and a large epidemiological study of drinking water quality and human health were completed. ORNL's first scanning tunneling microscope (STM) has achieved single atom resolution and has produced some of the world's best images of single atoms on the surface of a silicon crystal. The Biological and Radiation Physics Section, designed and constructed a soft x-ray spectrometer which has exhibited a measuring efficiency that is 10,000 times higher than other equipment. 1164 refs.

  12. E. coli low molecular weight penicillin binding proteins help orient septal FtsZ, and their absence leads to asymmetric cell division and branching

    PubMed Central

    Potluri, Lakshmi-Prasad; de Pedro, Miguel; Young, Kevin D.

    2012-01-01

    Escherichia coli cells lacking low molecular weight penicillin binding proteins (LMW PBPs) exhibit morphological alterations that also appear when the septal protein FtsZ is mislocalized, suggesting that peptidoglycan modification and division may work together to produce cell shape. We found that in strains lacking PBP5 and other LMW PBPs, higher FtsZ concentrations increased the frequency of branched cells and incorrectly oriented Z rings by 10- to 15-fold. Invagination of these rings produced improperly oriented septa, which in turn gave rise to asymmetric cell poles that eventually elongated into branches. Branches always originated from the remnants of abnormal septation events, cementing the relationship between aberrant cell division and branch formation. In the absence of PBP5, PBP6 and DacD localized to nascent septa, suggesting that these PBPs can partially substitute for the loss of PBP5. We propose that branching begins when mislocalized FtsZ triggers the insertion of inert peptidoglycan at unusual positions during cell division. Only later, after normal cell wall elongation separates the patches, do branches become visible. Thus, a relationship between the LMW PBPs and cytoplasmic FtsZ ultimately affects cell division and overall shape. PMID:22390731

  13. [Research strategy on molecular identification of animal medical material].

    PubMed

    Huang, Luqi; Tang, Shihuan; Li, Junde; Zhao, Jingxue

    2011-02-01

    This paper summarized and analyzed the status quo and problems about molecular identification of animal medical material, based on the facts, we proposed some research strategies, including uniting to tackle key problems, expanding the research species, accelerating manufacture and generalization of molecular identification kit, priming the research project of DNA barcoding, and establishing standard database on animal medical material.

  14. 2010 Atomic & Molecular Interactions Gordon Research Conference

    SciTech Connect

    Todd Martinez

    2010-07-23

    The Atomic and Molecular Interactions Gordon Conferences is justifiably recognized for its broad scope, touching on areas ranging from fundamental gas phase and gas-condensed matter collision dynamics, to laser-molecule interactions, photophysics, and unimolecular decay processes. The meeting has traditionally involved scientists engaged in fundamental research in gas and condensed phases and those who apply these concepts to systems of practical chemical and physical interest. A key tradition in this meeting is the strong mixing of theory and experiment throughout. The program for 2010 conference continues these traditions. At the 2010 AMI GRC, there will be talks in 5 broadly defined and partially overlapping areas of intermolecular interactions and chemical dynamics: (1) Photoionization and Photoelectron Dynamics; (2) Quantum Control and Molecules in Strong Fields; (3) Photochemical Dynamics; (4) Complex Molecules and Condensed Phases; and (5) Clusters and Reaction Dynamics. These areas encompass many of the most productive and exciting areas of chemical physics, including both reactive and nonreactive processes, intermolecular and intramolecular energy transfer, and photodissociation and unimolecular processes. Gas phase dynamics, van der Waals and cluster studies, laser-matter interactions and multiple potential energy surface phenomena will all be discussed.

  15. High Energy Physics Division: Semiannual report of research activities, July 1, 1988--December 31, 1988

    SciTech Connect

    Not Available

    1988-01-01

    This paper briefly discusses progress at Argonne National Laboratory in the following areas: Experimental Program; Theory Program; Experimental Facilities Research; Accelerator Research and Development; and SSC Detector Research and Development.

  16. Mars Molecular and Isotopic Analysis Research Study

    NASA Technical Reports Server (NTRS)

    Manning, Heidi L. K.

    1998-01-01

    Recently, the Martian atmosphere and surface constituents have become of great interest. The Viking in situ gas chromatograph mass spectrometer experiment contributed greatly to our knowledge of the composition of the Martian atmosphere. However, important questions remain such as the abundance of water on Mars. The Viking experiment employed solid reagents to enhance their carbon measurements. Techniques of chemical conversion using simple solid reagents have advanced considerably in the past 20 years. In this investigation we researched the advancements in techniques to reversibly adsorb and desorb water and focused on the techniques potentially useful for the temperatures and pressures on the Martian surface. During the granting period from June 15, 1998 to August 14, 1998, a literature study of the material appropriate for use in a chemical conversion device and the availability of these materials were undertaken. The focus of this investigation was searching for methods and materials potentially useful in enhancing the measurements of water. Three different methods were considered for the means to extract water from a given gas sample. These methods included adsorption in a desiccant, adsorption on a clean metal surface, and adsorption in a carbon molecular sieve or zeolite. Each method was evaluated with feasibility and reversibility in mind. By far the simplest and perhaps cheapest way to remove water from a gaseous sample is by means of a bulk desiccant. Desiccants are commercially available from many companies including those that supply chemicals. The main feature of a desiccant is its ability to rapidly bind or absorb water from the atmosphere. Calcium chloride, for example, is frequently incorporated into drying tubes by organic chemists when reactions require the absence of water. Other desiccants include sodium hydroxide, calcium hydride, and commercial products such as Drierite, available from Aldrich Chemical. The disadvantage to most desiccants is

  17. Mars Molecular and Isotopic Analysis Research Study

    NASA Technical Reports Server (NTRS)

    Manning, Heidi L. K.

    1998-01-01

    Recently, the Martian atmosphere and surface constituents have become of great interest. The Viking in situ gas chromatograph mass spectrometer experiment contributed greatly to our knowledge of the composition of the Martian atmosphere. However, important questions remain such as the abundance of water on Mars. The Viking experiment employed solid reagents to enhance their carbon measurements. Techniques of chemical conversion using simple solid reagents have advanced considerably in the past 20 years. In this investigation we researched the advancements in techniques to reversibly adsorb and desorb water and focused on the techniques potentially useful for the temperatures and pressures on the Martian surface. During the granting period from June 15, 1998 to August 14, 1998, a literature study of the material appropriate for use in a chemical conversion device and the availability of these materials were undertaken. The focus of this investigation was searching for methods and materials potentially useful in enhancing the measurements of water. Three different methods were considered for the means to extract water from a given gas sample. These methods included adsorption in a desiccant, adsorption on a clean metal surface, and adsorption in a carbon molecular sieve or zeolite. Each method was evaluated with feasibility and reversibility in mind. By far the simplest and perhaps cheapest way to remove water from a gaseous sample is by means of a bulk desiccant. Desiccants are commercially available from many companies including those that supply chemicals. The main feature of a desiccant is its ability to rapidly bind or absorb water from the atmosphere. Calcium chloride, for example, is frequently incorporated into drying tubes by organic chemists when reactions require the absence of water. Other desiccants include sodium hydroxide, calcium hydride, and commercial products such as Drierite, available from Aldrich Chemical. The disadvantage to most desiccants is

  18. About the Gastrointestinal and Other Cancers Research Group | Division of Cancer Prevention

    Cancer.gov

    The Gastrointestinal and Other Cancers Research Group conducts and supports prevention and early detection research on colorectal, esophageal, liver, pancreatic, and hematolymphoid cancers, as well as new approaches to clinical prevention studies including cancer immunoprevention. |

  19. NCORP Thrives in Diverse Communities Carrying Out a Wide Range of Research | Division of Cancer Prevention

    Cancer.gov

    The NCI Community Oncology Research Program (NCORP) achieved numerous successes through research and collaborations in its second year, NCORP director Worta McCaskill-Stevens told the group’s annual meeting October 17-18, 2016 in Bethesda, Maryland. |

  20. Occupational health and environment research 1983: Health, Safety, and Environment Division. Progress report

    SciTech Connect

    Voelz, G.L.

    1985-05-01

    The primary responsibility of the Health, Safety, and Environment (HSE) Division at the Los Alamos National Laboratory is to provide comprehensive occupational health and safety programs, waste processing, and environmental protection. These activities are designed to protect the workers, the public, and the environment. Evaluation of respiratory protective equipment included the XM-30 and M17A1 military masks, use of MAG-1 spectacles in respirators, and eight self-contained units. The latter units were used in an evaluation of test procedures used for Bureau of Mines approval of breathing apparatuses. Analyses of air samples from field studies of a modified in situ oil shale retorting facility were performed for total cyclohexane extractables and selected polynuclear aromatic hydrocarbons. Aerosols generation and characterization of effluents from oil shale processing were continued as part of an inhalation toxicology study. Additional data on plutonium excretion in urine are presented and point up problems in using the Langham equation to predict plutonium deposition in the body from long-term excretion data. Environmental surveillance at Los Alamos during 1983 showed the highest estimated radiation dose from Laboratory operations to be about 26% of the natural background radiation dose. Several studies on radionuclides and their transport in the Los Alamos environment are described. The chemical quality of surface and ground water near the geothermal hot dry rock facility is described. Short- and long-term consequences to man from releases of radionuclides into the environment can be simulated by the BIOTRAN computer model, which is discussed brirfly.

  1. Radiological and Environmental Research Division: ecology. Annual report, January-December 1982

    SciTech Connect

    Not Available

    1983-09-01

    This is the annual report of the Radiological and Environmental Division of the Argonne National Laboratory for 1982. Studies of the effects of ozone on crop growth and yield have been carried out by the Terrestrial Ecology Group for winter wheat and for sorghum. The Microcosms for Acid Rain Studies (MARS) facility was completed in the early summer. Controlled investigations of plant and soil responses in acid rain were initiated with crop plants grown in two different midwestern soil types. The Transuranics Group has found that the solubility and adsorptive behavior of plutonium previously observed at fallout concentrations in natural waters (approx. 10/sup -16/ to 10/sup -18/ M) is applicable at plutonium concentrations as high as 10/sup -8/ M. The Lake Michigan eutrophication model has been adapted to operation in a Monte Carlo mode. Simulations based on yearly phosphorus loadings and winter conditions were selected at random from prescribed probability distributions and used to estimate some of the uncertainties associated with model forecasts of Lake Michigan water quality.

  2. Research of automatic counting paper money technology based on two-dimensional histogram θ-division

    NASA Astrophysics Data System (ADS)

    Liu, Yongze; Meng, Qingshen; Song, Xuejun; Li, Aiting

    2011-12-01

    At present, the most technology of counting money is to use the money counter in financial fields. The paper presents a new method for automatic counting paper money which is based on image processing technology. Firstly, the paper money image is acquired by CCD. After analyzing the feature of image, we find that in Cr-space the edge of each paper money is enhanced. Then we use the north-west sobel operator for filtering and north sobel operator for detecting edge. Although the image-processed better highlight the edge of each paper money, the edge is rough and its variance is high. It is hardly to threshold the image for getting the single-pixel edge linked. After Different segmentation algorithm was been used for deriving the edge of paper money, we find the Two-dimensional Histogram θ-division algorithm is suitable for our purpose. The experimental result is proved satisfied. The detecting rate reached 100% in controlled environment for RMB. However, if we want to detect other kinds of paper money such as dollar, there also have several problems to be solved.

  3. About the Prostate and Urologic Cancer Research Group | Division of Cancer Prevention

    Cancer.gov

    The Prostate and Urologic Cancer Research Group conducts and supports research on prostate and bladder cancers, and new approaches to clinical prevention studies including cancer immunoprevention. The group develops, implements and monitors research efforts in chemoprevention, nutrition, genetic, and immunologic interventions, screening, early detection and other prevention strategies. |

  4. High Energy Physics Division semiannual report of research activities, January 1--June 30, 1997

    SciTech Connect

    Norem, J.; Rezmer, R.; Wagner, R.

    1997-12-01

    This report is divided into: the experimental research program; theoretical physics program; accelerator research and development; and divisional computing activities. The experimental research program covers: experiments with data; experiments in planning or construction; and detector development. Work done for this period is summarized for each area.

  5. About the Community Oncology and Prevention Trials Research Group | Division of Cancer Prevention

    Cancer.gov

    The Community Oncology and Prevention Trials Research Group supports clinical oncology trials in cancer prevention and control in community settings. The group also supports investigator-initiated research projects in supportive, palliative and end-of-life care, and coordinates clinical oncology research projects with other NCI programs to be done in the community setting. |

  6. How to Begin Molecular Research of Metabolic Diseases.

    PubMed

    Yoon, Bo Kyung; Kim, Jae Woo

    2016-12-01

    Advancing higher education is an important goal within the scientific and medical communities. The Korean Endocrine Society has worked with medical researchers who hope to conduct molecular research in addition to their clinical education. Based on concepts developed at a 2016 educational workshop, this article summarizes the requirement for a strong foundation in the performance of molecular research. Specifically, recent articles in metabolic research are highlighted to provide examples of commonly used techniques in this field of study.

  7. How to Begin Molecular Research of Metabolic Diseases

    PubMed Central

    Yoon, Bo Kyung

    2016-01-01

    Advancing higher education is an important goal within the scientific and medical communities. The Korean Endocrine Society has worked with medical researchers who hope to conduct molecular research in addition to their clinical education. Based on concepts developed at a 2016 educational workshop, this article summarizes the requirement for a strong foundation in the performance of molecular research. Specifically, recent articles in metabolic research are highlighted to provide examples of commonly used techniques in this field of study. PMID:28029022

  8. Molecular Analysis Research at Community College of Philadelphia

    DTIC Science & Technology

    2015-09-21

    Approved for Public Release; Distribution Unlimited Final Report: Molecular Analysis Research at Community College of Philadelphia The views, opinions...YOUR FORM TO THE ABOVE ADDRESS. Community College of Philadelphia Community College of Philadelphia 1700 Spring Garden Street Philadelphia, PA 19130...Molecular Analysis Research at Community College of Philadelphia Report Title AXIMA Assurance mass spectrometer, Leica DMI-8 fluorescent microscope

  9. Energy and Environment Division, Environmental Research Program, annual report FY 1982

    SciTech Connect

    Not Available

    1983-07-01

    The primary concern of the Environmental Research Program is the understanding of pollutant formation, transport, and transformation and the impacts of pollutants on the environment. These impacts include global, regional, and local effects on the atmosphere and hydrosphere, and on certain aspects of human health. This multidisciplinary research program includes fundamental and applied research in physics, chemistry, and biology, as well as research on the development of advanced methods of measurement and analysis. During FY 1982, research was concentrated on atmospheric physics and chemistry, applied physics and laser spectroscopy, combustion research, environmental effects of oil shale processing, fresh-water ecology and acid precipitation, trace element analysis for the investigation of present and historical environmental impacts, and a continuing survey of instrumentation for environmental monitoring. Separate abstracts have been prepared for each research task for inclusion in the Energy Data Base.

  10. Molecular Profiling of Stomatal Meristemoids Reveals New Component of Asymmetric Cell Division and Commonalities among Stem Cell Populations in Arabidopsis[C][W][OA

    PubMed Central

    Pillitteri, Lynn Jo; Peterson, Kylee M.; Horst, Robin J.; Torii, Keiko U.

    2011-01-01

    The balance between maintenance and differentiation of stem cells is a central question in developmental biology. Development of stomata in Arabidopsis thaliana begins with de novo asymmetric divisions producing meristemoids, proliferating precursor cells with stem cell–like properties. The transient and asynchronous nature of the meristemoid has made it difficult to study its molecular characteristics. Synthetic combination of stomatal differentiation mutants due to loss- or gain-of-function mutations in SPEECHLESS, MUTE, and SCREAM create seedlings with an epidermis overwhelmingly composed of pavement cells, meristemoids, or stomata, respectively. Through transcriptome analysis, we define and characterize the molecular signatures of meristemoids. The reporter localization studies of meristemoid-enriched proteins reveals pathways not previously associated with stomatal development. We identified a novel protein, POLAR, and demonstrate through time-lapse live imaging that it exhibits transient polar localization and segregates unevenly during meristemoid asymmetric divisions. The polar localization of POLAR requires BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE. Comparative bioinformatic analysis of the transcriptional profiles of a meristemoid with shoot and root apical meristems highlighted cytokinin signaling and the ERECTA family receptor-like kinases in the broad regulation of stem cell populations. Our work reveals molecular constituents of stomatal stem cells and illuminates a common theme among stem cell populations in plants. PMID:21963668

  11. Graduate student theses supported by Carbon Dioxide Research Division, Office of Basic Energy Sciences, US Department of Energy

    SciTech Connect

    Millemann, R.E.

    1987-09-01

    The US Department of Energy's Carbon Dioxide Research Division (CDRD) has a strong commitment to support graduate education. The purpose of this report was to summarize information on thesis research supported by CDRD and to make it available to carbon dioxide researchers and other interested persons. To date, 25 Ph.D. and 23 Master's theses, including 4 internship reports for the M.En. degree from Miami University, have been written based on research supported in whole or in part by CDRD funds. Of these, 16 are in the Carbon Cycle area, 11 relate to Climate, 17 to Vegetation Response, 3 to Sea Level, and 4 pertain to the Carbon Dioxide Information and Analysis Center with a few theses relevant to more than one area. The following four lists appear in this report: An Author List with the complete thesis citation, names of the major professor, major department, and contractor, and contract number. A Contractor List with the affiliation of each contractor and the thesis research supported by that contractor. A Program Area List with the theses grouped by subject area. Finally, a University List with the theses grouped by the degree-granting institutions.

  12. Compilation of reports from research supported by the Materials Engineering Branch, Division of Engineering: 1991--1993. Volume 2

    SciTech Connect

    Hiser, A.L.

    1994-06-01

    Since 1965, the Materials Engineering Branch, Division of Engineering, of the Nuclear Regulatory Commission`s Office of Nuclear Regulatory Research, and its predecessors dating back to the Atomic Energy Commission (AEC), has sponsored research programs concerning the integrity of the primary system pressure boundary of light water reactors. The components of concern in these research programs have included the reactor pressure vessel (RPV), steam generators, and the piping. These research programs have covered a broad range of topics, including fracture mechanics analysis and experimental work for RPV and piping applications, inspection method development and qualification, and evaluation of irradiation effects to RPV steels. This report provides as complete a listing as practical of formal technical reports submitted to the NRC by the investigators working on these research programs. This listing includes topical, final and progress reports, and is segmented by topic area. In many cases a report will cover several topics (such as in the case of progress reports of multi-faceted programs), but is listed under only one topic. Therefore, in searching for reports on a specific topic, other related topic areas should be checked also. The separate volumes of this report cover the following periods: Volume 1: 1965--1990 and Volume 2: 1991--1993.

  13. Interactive NCORP Map Details Community Research Sites | Division of Cancer Prevention

    Cancer.gov

    An interactive map of the NCI Community Oncology Research Program (NCORP) with detailed information on hundreds of community sites that take part in clinical trials is available on the NCORP website. NCORP Map NCORP Community Sites, Minority/Underserved Community Sites, and Research Bases |

  14. 11th Annual NIH Pain Consortium Symposium on Advances in Pain Research | Division of Cancer Prevention

    Cancer.gov

    The NIH Pain Consortium will convene the 11th Annual NIH Pain Consortium Symposium on Advances in Pain Research, featuring keynote speakers and expert panel sessions on Innovative Models and Methods. The first keynote address will be delivered by David J. Clark, MD, PhD, Stanford University entitled “Challenges of Translational Pain Research: What Makes a Good Model?” |

  15. About the Breast and Gynecologic Cancer Research Group | Division of Cancer Prevention

    Cancer.gov

    The Breast and Gynecologic Cancer Research Group conducts and fosters the development of research on the prevention and early detection of breast cancer, cervix and human papillomavirus (HPV)-related cancers, endometrial cancers, ovarian cancers, and precursor conditions related to these cancers. |

  16. Divisions of Labour: Activity Theory, Multi-Professional Working and Intervention Research

    ERIC Educational Resources Information Center

    Warmington, Paul

    2011-01-01

    This article draws upon, but also critiques, activity theory by combining analysis of how an activity theory derived research intervention attempted to address both everyday work practices and organisational power relationships among children's services professionals. It offers two case studies of developmental work research (DWR) interventions in…

  17. Research at the U.S. EPA’s Ground Water and Ecosystems Protection Division

    EPA Science Inventory

    The U.S. EPA’s Office of Research and Development (ORD) conducts leading-edge research and fosters the sound use of science and technology to fulfill the Agency's mission to protect human health and safeguard the natural environment. The mission of the Ground Water and Ecosystem...

  18. Health and Safety Research Division. Progress report, October 1, 1979-March 31, 1981

    SciTech Connect

    Not Available

    1981-08-01

    Research progress for the period October 1, 1979 through March 31, 1981 is reported. Research conducted by the Office of Integrated Assessments and Policy Analysis, Health Studies Section, Technology Assessments Section, Biological and Radiation Physics Section, and Chemical Physics Section is summarized. (ACR)

  19. Research at the U.S. EPA’s Ground Water and Ecosystems Protection Division

    EPA Science Inventory

    The U.S. EPA’s Office of Research and Development (ORD) conducts leading-edge research and fosters the sound use of science and technology to fulfill the Agency's mission to protect human health and safeguard the natural environment. The mission of the Ground Water and Ecosystem...

  20. Divisions of Labour: Activity Theory, Multi-Professional Working and Intervention Research

    ERIC Educational Resources Information Center

    Warmington, Paul

    2011-01-01

    This article draws upon, but also critiques, activity theory by combining analysis of how an activity theory derived research intervention attempted to address both everyday work practices and organisational power relationships among children's services professionals. It offers two case studies of developmental work research (DWR) interventions in…

  1. Becoming a Physicist: The Roles of Research, Mindsets, and Milestones in Upper-Division Student Perceptions

    ERIC Educational Resources Information Center

    Irving, Paul W.; Sayre, Eleanor C.

    2015-01-01

    As part of a longitudinal study into identity development in upper-level physics students, we used a phenomenographic research method to examine students' perceptions of what it means to be a physicist. Analysis revealed six different categories of perception of what it means to be a physicist. We found the following themes: research and its…

  2. Molecular Epidemiology for Vector Research on Leishmaniasis

    PubMed Central

    Kato, Hirotomo; Gomez, Eduardo A; Cáceres, Abraham G; Uezato, Hiroshi; Mimori, Tatsuyuki; Hashiguchi, Yoshihisa

    2010-01-01

    Leishmaniasis is a protozoan disease caused by the genus Leishmania transmitted by female phlebotomine sand flies. Surveillance of the prevalence of Leishmania and responsive vector species in endemic and surrounding areas is important for predicting the risk and expansion of the disease. Molecular biological methods are now widely applied to epidemiological studies of infectious diseases including leishmaniasis. These techniques are used to detect natural infections of sand fly vectors with Leishmania protozoa and are becoming powerful tools due to their sensitivity and specificity. Recently, genetic analyses have been performed on sand fly species and genotyping using PCR-RFLP has been applied to the sand fly taxonomy. In addition, a molecular mass screening method has been established that enables both sand fly species and natural leishmanial infections to be identified simultaneously in hundreds of sand flies with limited effort. This paper reviews recent advances in the study of sand flies, vectors of leishmaniasis, using molecular biological approaches. PMID:20617005

  3. Quarterly progress report for the Chemical and Energy Research Section of the Chemical Technology Division, April--June 1997

    SciTech Connect

    Jubin, R.T.

    1998-06-01

    The Chemical and Energy Research Section conducts basic and applied research and development in chemical engineering, applied chemistry, and bioprocessing, with an emphasis on energy-driven technologies and advanced chemical separations for nuclear and waste applications. The report describes the various tasks performed within six major areas of research: Hot Cell Operations, Process Chemistry and thermodynamics, Separations and Materials Synthesis, Solution Thermodynamics, biotechnology Research, and Molecular Studies. The name of a technical contact is included with each task described, and readers are encouraged to contact these individuals if they need additional information.

  4. Molecular Characterization of Resistance-Nodulation-Division Transporters from Solvent- and Drug-Resistant Bacteria in Petroleum-Contaminated Soil

    PubMed Central

    Meguro, Norika; Kodama, Yumiko; Gallegos, Maria-Trinidad; Watanabe, Kazuya

    2005-01-01

    PCR assays for analyzing resistance-nodulation-division transporters from solvent- and drug-resistant bacteria in soil were developed. Sequence analysis of amplicons showed that the PCR successfully retrieved transporter gene fragments from soil. Most of the genes retrieved from petroleum-contaminated soils formed a cluster (cluster PCS) that was distantly related to known transporter genes. Competitive PCR showed that the abundance of PCS genes is increased in petroleum-contaminated soil. PMID:15640241

  5. International Federation of Library Associations Annual Conference Papers. General Research Libraries Division: Parliamentary Libraries and National Libraries Sections (47th, Leipzig, East Germany, August 17-22, 1981).

    ERIC Educational Resources Information Center

    Gude, Gilbert; And Others

    This set of papers presented to the General Research Libraries Division of the International Federation of Library Associations (IFLA) during its 47th annual conference (1981) includes: "The Effect of the Introduction of Computers on Library and Research Staff," by Gilbert Gude; "Libraries as Information Service Agencies…

  6. International Federation of Library Associations Annual Conference Papers. General Research Libraries Division: Parliamentary Libraries and National Libraries Sections (47th, Leipzig, East Germany, August 17-22, 1981).

    ERIC Educational Resources Information Center

    Gude, Gilbert; And Others

    This set of papers presented to the General Research Libraries Division of the International Federation of Library Associations (IFLA) during its 47th annual conference (1981) includes: "The Effect of the Introduction of Computers on Library and Research Staff," by Gilbert Gude; "Libraries as Information Service Agencies…

  7. The John Milner Nutrition and Cancer Prevention Research Practicum | Division of Cancer Prevention

    Cancer.gov

    Attendee Testimonial Plenty of Food for Thought Served Up at the John Milner Nutrition and Cancer Prevention Research Practicum by Julia Tobacyk Read the Testimonial (DOC, 3.3MB) Date: March 12-16, 2018 |

  8. Accelerator and Fusion Research Division annual report, fiscal year 1980, October 1979-September 1980

    SciTech Connect

    Not Available

    1981-03-01

    Research during October 1979 to September 1980 is summarized. Areas covered include: accelerator operations; positron-electron project; stochastic beam cooling; high-field superconducting magnets; accelerator theory; neutral beam sources; and heavy ion fusion. (GHT)

  9. About the Environmental Public Health Division (EPHD) of EPA's National Health and Environmental Effects Research Laboratory

    EPA Pesticide Factsheets

    The EPHD performs integrated epidemiological, clinical, animal and cellular biological research and statistical modeling to provide the scientific foundation in support of hazard identification, risk assessment, and standard setting.

  10. Health and Safety Research Division progress report, July 1, 1984-September 30, 1985

    SciTech Connect

    Not Available

    1986-01-01

    This report summarizes progress made for the period July 1984 through September 1985. Sections describe research in health studies, dosimetry and biophysical transport, biological and radiation physics, chemical physics, and risk analysis. (ACR)

  11. About the Chemopreventive Agent Development Research Group | Division of Cancer Prevention

    Cancer.gov

    The Chemopreventive Agent Development Research Group promotes and supports research on early chemopreventive agent development, from preclinical studies to phase I clinical trials. The group’s projects aim to identify and develop prevention agents with the potential to block, reverse, or delay the early stages of cancer. The overarching goal is to determine positive and negative predictive values of preclinical models for clinical development. |

  12. Puerto Rico NCI Community Oncology Research Program Minority/Underserved | Division of Cancer Prevention

    Cancer.gov

    DESCRIPTION (provided by applicant): The Puerto Rico NCI Community Oncology Research Program (PRNCORP) will be the principal organization in the island that promotes cancer prevention, control and screening/post-treatment surveillance clinical trials. It will conduct cancer care delivery research and will provide access to treatment and imaging clinical trials conducted under the reorganization of the National Clinical Trials Network (NCTN). It will evaluate disparity issues and outcomes in cancer care delivery and treatments. |

  13. About the Lung and Upper Aerodigestive Cancer Research Group | Division of Cancer Prevention

    Cancer.gov

    The Lung and Upper Aerodigestive Cancer Research Group conducts and supports research on the prevention and early detection of lung and head and neck cancers, as well as new approaches to clinical prevention studies including cancer immunoprevention.Phase 0/I/II Cancer Prevention Clinical Trials ProgramThe group jointly administers the Phase 0/I/II Cancer Prevention Clinical Trials Program evaluating new agents, surrogate biomarkers, and technologies to identify premalignant lesions, and related cancers.  |

  14. COMBUSTION RESEARCH Chapter from the Energy and Environment Division Annual Report 1980

    SciTech Connect

    Authors, Various

    1981-05-01

    Combustion research at the Lawrence Berkeley Laboratory focuses on the study of the chemical and physical processes which are important in combustion. Two areas of application dominate; the control of combustion processes to allow the utilization of new fuels while limiting pollutant formation and the reduction of fire hazards accompanying energy generation and utilization technologies. Principal program areas are the interaction of fluid-mechanical turbulence and combustion, the development and application of new physical and chemical diagnostic techniques for combustion research, pollutant formation and destruction processes, theoretical and computational modeling of combustion processes, combustion processes in engines, fire science, and fire safety. Work is reported in these areas: ENGINE COMBUSTION AND IGNITION STUDIES; COMBUSTION CHEMISTRY AND POLLUTANT FORMATION; COMBUSTION FLUID MECHANICS; and FIRE RESEARCH.

  15. Institute for Molecular Medicine Research Program

    SciTech Connect

    Phelps, Michael E

    2012-12-14

    The objectives of the project are the development of new Positron Emission Tomography (PET) imaging instrumentation, chemistry technology platforms and new molecular imaging probes to examine the transformations from normal cellular and biological processes to those of disease in pre-clinical animal models. These technology platforms and imaging probes provide the means to: 1. Study the biology of disease using pre-clinical mouse models and cells. 2. Develop molecular imaging probes for imaging assays of proteins in pre-clinical models. 3. Develop imaging assays in pre-clinical models to provide to other scientists the means to guide and improve the processes for discovering new drugs. 4. Develop imaging assays in pre-clinical models for others to use in judging the impact of drugs on the biology of disease.

  16. Actions of prolactin on molecular research

    SciTech Connect

    Rillema, J.A.

    1987-01-01

    This book discusses the current understanding on the primary mechanisms by which prolactin regulates cellular proliferation and other metabolic processes (including gene expression) in its target cells. Reviews and analyzes information relative to the molecular events involved in the actions of prolactin on cells to provide a basis for determining the sequence of molecular reactions by which prolactin expresses its biological responses. The contents discussed are Activation of Molecular Events by Prolactin. Prolactin Interaction with its Receptors and Relationship to Subsequent Regulation of Metabolic Processes. Actions of Prolactin in the Brain. Models of Prolactin Action in Nonmmalian Vertebraes. Prolactin Regulation of Membrane Fludity and Prostglandin Formation. Role of Calcium Ions and Phospholipids in Prolactin Regulation of its Traget Cells. Synergistic Actions of Glucocorticoid and Prolactin in Murine Milk-Protein Gene Expression. Role of Polyamines in Prolactin Actions. Prolactin and the Regulation of Secretion Including Membrane Flow: Potential Roles for Tubulin and Microtubules. Protein Phosphorylation of Prlactin Target Tissue: Mammary Gland, Prolactin, Growth Factors, and Cell Growth.

  17. ECOLOGICAL RESEARCH AT THE MID-CONTINENT ECOLOGY DIVISION, U.S. EPA

    EPA Science Inventory

    This will be an informal lecture to introduce and describe some recent research efforts and results in the Great Lakes and other regions of interest. Examples will highlight several local, regiional, and nationally important issues relating to stressors of aquatic ecosystems. The...

  18. OVERVIEW OF ECOTOXICOLOGY RESEARCH AT THE US EPA NHEERL, MID-CONTINENT ECOLOGY DIVISION

    EPA Science Inventory

    The US Environmental Protection Agency is a regulatory agency whose mission is the protection of human health and the environment. The EPA has several Program and Regional Offices that form the regulatory side of the Agency. The Office of Research and Development (ORD) is a separ...

  19. OVERVIEW OF ECOTOXICOLOGY RESEARCH AT THE US EPA NHEERL, MID-CONTINENT ECOLOGY DIVISION

    EPA Science Inventory

    The US Environmental Protection Agency is a regulatory agency whose mission is the protection of human health and the environment. The EPA has several Program and Regional Offices that form the regulatory side of the Agency. The Office of Research and Development (ORD) is a separ...

  20. Effects of Arts Education on Participation in the Arts. Research Division Report 36.

    ERIC Educational Resources Information Center

    Bergonzi, Louis; Smith, Julia

    Using data from the 1992 Survey of Public Participation in the Arts (SPPA92), research focused on the question: "Does arts education make arts participation more accessible to Americans?" The effects of both school-based arts education and community-based arts education were considered and compared. Art forms considered in this…

  1. ECOLOGICAL RESEARCH AT THE MID-CONTINENT ECOLOGY DIVISION, U.S. EPA

    EPA Science Inventory

    This will be an informal lecture to introduce and describe some recent research efforts and results in the Great Lakes and other regions of interest. Examples will highlight several local, regiional, and nationally important issues relating to stressors of aquatic ecosystems. The...

  2. Research programs for Division of Chemical Sciences, Office of Basic Energy Sciences, Department of Energy

    SciTech Connect

    Not Available

    1988-01-01

    A chemical sciences review meeting was held in which research programs in chemistry were discussed. Major topics included: chemistry of actinides and fission products, interactions of solvents, solutes and surfaces in supercritical extraction, chemical and physical principles in multiphase separations, and chemical kinetics of enzyme catalyzed reactions. Individual projects are processed separately for the data bases. (CBS)

  3. Radiological and Environmental Research Division annual report, January-December 1980. Atmospheric physics

    SciTech Connect

    Not Available

    1981-08-01

    Contained are twenty-six abstracts of on-going research programs at Argonne National Laboratory concerning the modeling of environmental air pollutants concentration and transport for January-December 1980. Studies on pollutant transport modeling, fluid flow models, and atmospheric precipitations chemistry are included. (DLS)

  4. Health and Safety Research Division progress report, April 1, 1981-September 30, 1982

    SciTech Connect

    Not Available

    1983-02-01

    Research progress for the reporting period is briefly summarized for the following sections: (1) health studies, (2) technology assessments, (3) biological and radiation physics, (4) chemical physics, (5) Office of Risk Analysis, and (6) health and environmental risk and analysis. (ACR)

  5. Investigators' - Site Coordinators' Opportunity for Research Excellence (I-SCORE) Workshop | Division of Cancer Prevention

    Cancer.gov

    The DCP Organ Systems Research Groups develop, support and oversee clinical cancer prevention trials and promote participation by all populations. The trials are designed to evaluate the safety and efficacy of promising new preventive agents, the utility of novel biomarkers and the value of innovative technologies to identify premalignant lesions. The Consortia for Early Phase Prevention Trials program was created to facilitate the efficient implementation of these studies by teams of multidisciplinary investigators. |

  6. Accelerator and Fusion Research Division. Annual report, October 1978-September 1979

    SciTech Connect

    Not Available

    1980-03-01

    Topics covered include: Super HILAC and Bevalac operations; high intensity uranium beams line item; advanced high charge state ion source; 184-inch synchrocyclotron; VENUS project; positron-electron project; high field superconducting accelerator magnets; beam cooling; accelerator theory; induction linac drivers; RF linacs and storage rings; theory; neutral beam systems development; experimental atomic physics; neutral beam plasma research; plasma theory; and the Tormac project. (GHT)

  7. Loads and aeroelasticity division research and technology accomplishments for FY 1983 and plans for FY 1984

    NASA Technical Reports Server (NTRS)

    Gardner, J. E.; Dixon, S. C.

    1984-01-01

    Research was done in the following areas: development and validation of solution algorithms, modeling techniques, integrated finite elements for flow-thermal-structural analysis and design, optimization of aircraft and spacecraft for the best performance, reduction of loads and increase in the dynamic structural stability of flexible airframes by the use of active control, methods for predicting steady and unsteady aerodynamic loads and aeroelastic characteristics of flight vehicles with emphasis on the transonic range, and methods for predicting and reducing helicoper vibrations.

  8. NCI Approves Funding Plan for NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention

    Cancer.gov

    On June 24, 2014, the Scientific Program Leaders (SPL) of the National Cancer Institute (NCI) approved the funding plan for the NCI Community Oncology Research Program (NCORP), a national network of investigators, cancer care providers, academic institutions, and other organizations. NCORP will conduct multi-site cancer clinical trials and studies in diverse populations in community-based healthcare systems across the United States. The program will receive $93 million a year for five years. |

  9. Radiological and Environmental Research Division annual report, January-December 1982. Atmospheric physics. Part 4

    SciTech Connect

    Not Available

    1984-01-01

    The first article in this report, although dealing with simple terrain, summarizes an effort to obtain measures of parameters important in transport and diffusion in the lower atmosphere solely by use of a Doppler acoustic sounding system. The second article describes participation in a multiagency experiment (Shoreline Environment Atmospheric Dispersion Experiment, SEADEX) to study the fate of materials released over a surface with notable surface nonuniformities, specifically at a coastal nuclear power plant during onshore flow conditions. The third and fourth articles in this report address research on the local behavior of pollutants emitted from diesel engines in urban areas. Most effort was directed toward field studies on circulation patterns in street canyons, exchange rates with the atmosphere above rooftops, and characterization of particles in outdoor urban microclimates. The remainder of the report is quite diverse and contains multiple articles on perhaps only one or two types of research. One is numerical modeling of the behavior of atmospheric pollutants, especially gaseous and particulate substances associated with acid deposition. The modeling and theoretical capabilities have been developed in part to consider potential nonlinear relationships between anthropogenic emissions of sulfur and nitrogen compounds and the distant deposition of resulting acidifying substances. On the experimental side, field phases of research designed to compare methods of analyses of precipitation samples and to study local urban effects on precipitation chemistry were completed. Each report is indexed separately.

  10. [New concepts in molecular biology applied to traslational research].

    PubMed

    Mengual, Lourdes

    2013-06-01

    This chapter intends to introduce the new concepts that have been established in molecular biology over the last years and are being applied in translational research. The chapter is divided in four big blocks, which treat the molecular biology concepts and techniques in relation to DNA, RNA, proteins and metabolites, respectively. Moreover, we give examples of translational application of these new methodologies described.

  11. Native Americans and the Geosciences: Problems With Societally Driven Research, Cultural and Racial Divisions

    NASA Astrophysics Data System (ADS)

    Redsteer, M. H.; James, K.

    2004-12-01

    Why are Native Americans absent from the geosciences? It doesn't seem to make sense when one view common to most traditional Native communities is earth and ecosystem stewardship, i.e. respect for Mother Earth. In addition, Native American communities could benefit from contributions made through earth science research. Land, and the natural resources that accompany it, are most tribes' greatest assets. Natural resource and land-use plans require information on geologic hazards, water quality and availability, soils, and environmentally sensitive areas: all data that are sorely lacking in Native communities. Native communities, with rapidly growing populations, desperately need geologic information for planning urban development. Even so, there are several reasons for a lack of interest in the geosciences: Mainstream science has historically served non-Native society to the detriment of Native communities, leaving few positive examples of earth science research for communities to draw from. Native North American communities have suffered greater harm from resource exploitation and have gained less from natural resource development than non-Native communities. Moreover, the earth scientist is usually the one who begins the assessing what is available for corporate exploitation, making the role of earth scientist adversarial. Racism, that begins at the elementary school level or earlier, leaves students feeling inadequate to pursue any degree, let alone those that are considered more challenging. Western science has a long history of denigrating indigenous knowledge and beliefs, producing a social stigma that Native American scientists must overcome. In addition, research tends to be narrowly focused, and based on the desire for individual academic achievement. This attitude counters cultural values of most Native groups, who seek to serve the collective group, rather than seeking self promotion.

  12. Annual report and summaries of FY 1983 activities supported by the Division of Biological Energy Research

    SciTech Connect

    Rabson, R.

    1983-10-01

    Summaries of research performed in FY 1983 are presented. Representative research areas include: (1) progress was made in modifying the Agrobacterium tumefaciens Ti plasmid as a vector in the transfer of DNA in higher plants. The plasmid was disarmed by genetically altering that information which is responsible for unwanted tumor formation in recipient plants. In addition it was demonstrated that antibiotic resistance as a representative genetic character may be transferred by the Ti plasmid to a recipient plant culture; (2) by using appropriately constituted genetic lines of maize it has been possible by following male sterility restorer function to measure for the first time the frequency and character of genetic transposition events in a higher organism; (3) the gene coding for susceptibility to the herbicide atrazine in higher plants has been identified, cloned, and sequenced. A mutant gene which is responsible for resistance to the herbicide has likewise been studied. The difference between the two is one nucleotide in the DNA sequence; and (4) amino acid sequences of a number of proteins of the smallest functional photosynthetic particle, known as the reaction center, of the photosynthetic bacterium Rhodopseudomonas capsulata have been determined by cloning and sequencing the corresponding DNA. This information has led to new insights concerning the structural and functional nature of the proteins in photosynthesis.

  13. IFLA General Conference, 1986. Education and Research Division. Section: Library History and Library Theory and Research. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    Papers on library history and library theory and research presented at the 1986 International Federation of Library Associations (IFLA) conference include: (1) "The History of Western Literature Library Collections in Japan" (Yoshitomi Okazaki, Japan); (2) "Trends of Library History Research in Japan" (Hiroshi Kawai, Yukio…

  14. IFLA General Conference, 1986. Education and Research Division. Section: Library History and Library Theory and Research. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    Papers on library history and library theory and research presented at the 1986 International Federation of Library Associations (IFLA) conference include: (1) "The History of Western Literature Library Collections in Japan" (Yoshitomi Okazaki, Japan); (2) "Trends of Library History Research in Japan" (Hiroshi Kawai, Yukio…

  15. [The latest research of the molecular biomarker in prostate cancer].

    PubMed

    Ashikari, Daisaku; Takahashi, Satoru

    2016-01-01

    The incidence of prostate cancer is rapidly increasing in Japan. Currently, the biomarker of prostate cancer is widely used in clinical is serum PSA only. We need to develop novel molecular markers (biomarkers) that diagnose early prostate cancer so that we can treat appropriately. Recently, the whole genome sequencing analysis has advanced that has made finding of novel molecular markers easier. The best molecular markers identified using personalized genome information will be useful to select appropriate treatment. These therapeutic options for each patient will improve the survival rate. We give an outline about the latest molecular marker basic research with reference to the articles.

  16. Structures and Acoustics Division

    NASA Technical Reports Server (NTRS)

    Acquaviva, Cynthia S.

    2001-01-01

    The Structures and Acoustics Division of the NASA Glenn Research Center is an international leader in rotating structures, mechanical components, fatigue and fracture, and structural aeroacoustics. Included in this report are disciplines related to life prediction and reliability, nondestructive evaluation, and mechanical drive systems. Reported is a synopsis of the work and accomplishments completed by the Division during the 1997, 1998, and 1999 calendar years. A bibliography containing 93 citations is provided.

  17. Structures and Acoustics Division

    NASA Technical Reports Server (NTRS)

    Acquaviva, Cynthia S.

    1999-01-01

    The Structures and Acoustics Division of NASA Glenn Research Center is an international leader in rotating structures, mechanical components, fatigue and fracture, and structural aeroacoustics. Included are disciplines related to life prediction and reliability, nondestructive evaluation, and mechanical drive systems. Reported are a synopsis of the work and accomplishments reported by the Division during the 1996 calendar year. A bibliography containing 42 citations is provided.

  18. Research results reported by OEO summer (1981) student employees of LLNL working with Earth Sciences (K) Division personnel

    SciTech Connect

    Doyle, M. C.; Griffith, P. J.; Kreevoy, E. P.; Turner, III, H. J.; Tatman, D. A.

    1982-01-01

    Significant experimental results were achieved in a number of research programs that were carried out during the summer of 1981 by students sponsored by the Office of Equal Opportunity at the Lawrence Livermore National Laboratory. These students were working with Earth Sciences (K) Division personnel. Accomplishments include the following: (1) preparation of post-burn stratigraphic sections for the Hoe Creek III experiment, Underground Coal Gasification project; (2) preparation of miscellaneous stratigraphic sections in the Climax granite near the Spent Fuel Test, Nevada Test Site, for the Waste Isolation Project; (3) confirmation of the applicability of a new theory relating to subsidence (solid matrix movement); (4) experimental confirmation that organic groundwater contaminants produced during an underground coal gasification experiment can be removed by appropriate bacterial treatment; (5) development of data supporting the extension of the Greenville Fault Zone into the Northern Diablo Range (Alameda and Santa Clara Counties, California); (6) completion of a literature review on hazardous waste (current disposal technology, regulations, research needs); (7) preparation of a map showing levels of background seismic noise in the USSR; (8) demonstration of a correlation of explosion size with the P-wave magnitude of the seismic signal produced by the explosion; and (9) reduction of data showing the extent of ground motion resulting from subsidence in the vicinity of the Hoe Creek III experiment, Underground Coal Gasification Project.

  19. IFLA General Conference, 1991. Division of Education and Research: Section of Education and Training; Continuing Professional Education (RT); Section of Library Theory and Research; Library History (RT); Research in Reading (RT); Editors of Library Journals (RT). Booklet 7.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    The 12 papers in this collection were presented at 6 sections of the Division of Education and Research: (1) "Emergence of the Asian Pacific Area and Its Impact on Education and Training of Librarians" (Maxine K. Rochester, Australia); (2) "The Cultural Aspects of Colonialism: Case Study of the Relevance of the Imported Curriculum…

  20. IFLA General Conference, 1991. Division of Education and Research: Section of Education and Training; Continuing Professional Education (RT); Section of Library Theory and Research; Library History (RT); Research in Reading (RT); Editors of Library Journals (RT). Booklet 7.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, The Hague (Netherlands).

    The 12 papers in this collection were presented at 6 sections of the Division of Education and Research: (1) "Emergence of the Asian Pacific Area and Its Impact on Education and Training of Librarians" (Maxine K. Rochester, Australia); (2) "The Cultural Aspects of Colonialism: Case Study of the Relevance of the Imported Curriculum…

  1. Intelligent tutoring systems research in the training systems division: Space applications

    NASA Technical Reports Server (NTRS)

    Regian, J. Wesley

    1988-01-01

    Computer-Aided Instruction (CAI) is a mature technology used to teach students in a wide variety of domains. The introduction of Artificial Intelligence (AI) technology of the field of CAI has prompted research and development efforts in an area known as Intelligent Computer-Aided Instruction (ICAI). In some cases, ICAI has been touted as a revolutionary alternative to traditional CAI. With the advent of powerful, inexpensive school computers, ICAI is emerging as a potential rival to CAI. In contrast to this, one may conceive of Computer-Based Training (CBT) systems as lying along a continuum which runs from CAI to ICAI. Although the key difference between the two is intelligence, there is not commonly accepted definition of what constitutes an intelligent instructional system.

  2. Eva Szabo, MD | Division of Cancer Prevention

    Cancer.gov

    Dr. Eva Szabo is Chief of the Lung and Upper Aerodigestive Cancer Research Group at the NCI Division of Cancer Prevention. She graduated from Yale University with a BS in Molecular Biophysics and Biochemistry, received her MD from Duke University, and completed her internal medicine residency at Bellevue-NYU Medical Center. After completing her medical oncology fellowship at the National Cancer Institute, Dr. |

  3. Water Resources Research October 1, 1979 - September 30, 1980: Summary statements of research activities by the Water Resources Division

    USGS Publications Warehouse

    ,

    1981-01-01

    Research in the WRD had its beginnings in the late 1950's when the "core research" line item was added to the Congressional budget. Since this time the Federal program has grown from a "basic sciences" program to one that includes a broad spectrum of basic and applied scientific investigations. Water resources research in WRD includes the study of water in all its phases and uses the basic sciences of mathematics, chemistry, physics, biology, geology and engineering to gain a fundamental understanding of the processes that affect the movement of water and its chemical constituents through hydrologic systems. The basic knowledge and methodologies derived from water resources research are applicable not only to the solution of current problems associated with the Nation's water resources, but also to anticipated hydrologic issues.

  4. Theoretical Research Investigation for Air Molecular Calculations.

    DTIC Science & Technology

    1981-04-15

    reported energy at the barrier is -183.160 hartrees, a value already equal to the atomic dissociation limit (-183.159998) with his basiL set. Hopper’s...Michels Stewart Radiance Laboratories I De Angelo Drive Bedford, MA 01730 1 cy ATTN: R. D. Sharma I cy ATTN: J. C. Ulwick Aerodyne Research, Inc. Crosby

  5. Mountain-Plains Handbook: The Design and Operation of a Residential Family Based Education Program. Appendix. Supplement III to Volume 3. Measurement and Evaluation: The Research Services Division.

    ERIC Educational Resources Information Center

    Coyle, David A.; And Others

    One of five supplements which accompany chapter three of "Mountain-Plains Handbook: The Design and Operation of a Residential, Family Oriented Career Education Model" (CE 014 630), this document contains specific infomration concerning the curriculum component of the research services division. The curriculum products are listed by…

  6. Molecular dynamics simulation in virus research

    PubMed Central

    Ode, Hirotaka; Nakashima, Masaaki; Kitamura, Shingo; Sugiura, Wataru; Sato, Hironori

    2012-01-01

    Virus replication in the host proceeds by chains of interactions between viral and host proteins. The interactions are deeply influenced by host immune molecules and anti-viral compounds, as well as by mutations in viral proteins. To understand how these interactions proceed mechanically and how they are influenced by mutations, one needs to know the structures and dynamics of the proteins. Molecular dynamics (MD) simulation is a powerful computational method for delineating motions of proteins at an atomic-scale via theoretical and empirical principles in physical chemistry. Recent advances in the hardware and software for biomolecular simulation have rapidly improved the precision and performance of this technique. Consequently, MD simulation is quickly extending the range of applications in biology, helping to reveal unique features of protein structures that would be hard to obtain by experimental methods alone. In this review, we summarize the recent advances in MD simulations in the study of virus–host interactions and evolution, and present future perspectives on this technique. PMID:22833741

  7. The division of Chinese soft-shelled turtle intestine with molecular markers is slightly different from the morphological and histological observation.

    PubMed

    Zhang, Zuobing; Song, Ruxin; Xing, Xiao; Wang, Lan; Niu, Cuijuan

    2017-03-08

    Chinese soft-shelled turtle (Pelodiscus sinensis) is a commercially important species in Asian countries. Knowledge of its nutritional requirements and physiology is essential to its feed production. However, the lack of functional characterization of the intestine prevents well understanding of its absorption and utilization of nutritional materials. To solve this problem, this work utilized anatomical and histological method to characterize 9 segments sampled along the anterior-posterior axis of the intestine. Furthermore, nine genes, which have been well documented in the intestine division of mammals and fish were employed to functionally characterize the sampled 9 segments. Our results suggest that regions covering from the starting site to S3 (position at 29.9% of the total length from the starting of the intestine) are the equallant of mammalian dedumonen, those covering S4 (40.2%) and S5 (65.4%), posterior to S8 (92.7%) are the equivalent of mammalian ileum and large intestine, respectively. As to the region spaning S6 (81.3%) and S7 (87.3%), its functional equivalent (small intestine or large intestine) may be variable and depends on the functional genes. This molecular characterization put forward the functional understanding of intestine division of Chinese soft-shelled turtle, may contritube to nutritional physiology of the turtle, and promote Chinese soft-shelled turtle production. This article is protected by copyright. All rights reserved.

  8. The rise of the middle author: Investigating collaboration and division of labor in biomedical research using partial alphabetical authorship

    PubMed Central

    Smith, Elise; Joyal, Bruno; Larivière, Vincent

    2017-01-01

    Contemporary biomedical research is performed by increasingly large teams. Consequently, an increasingly large number of individuals are being listed as authors in the bylines, which complicates the proper attribution of credit and responsibility to individual authors. Typically, more importance is given to the first and last authors, while it is assumed that the others (the middle authors) have made smaller contributions. However, this may not properly reflect the actual division of labor because some authors other than the first and last may have made major contributions. In practice, research teams may differentiate the main contributors from the rest by using partial alphabetical authorship (i.e., by listing middle authors alphabetically, while maintaining a contribution-based order for more substantial contributions). In this paper, we use partial alphabetical authorship to divide the authors of all biomedical articles in the Web of Science published over the 1980–2015 period in three groups: primary authors, middle authors, and supervisory authors. We operationalize the concept of middle author as those who are listed in alphabetical order in the middle of an authors’ list. Primary and supervisory authors are those listed before and after the alphabetical sequence, respectively. We show that alphabetical ordering of middle authors is frequent in biomedical research, and that the prevalence of this practice is positively correlated with the number of authors in the bylines. We also find that, for articles with 7 or more authors, the average proportion of primary, middle and supervisory authors is independent of the team size, more than half of the authors being middle authors. This suggests that growth in authors lists are not due to an increase in secondary contributions (or middle authors) but, rather, in equivalent increases of all types of roles and contributions (including many primary authors and many supervisory authors). Nevertheless, we show that

  9. The rise of the middle author: Investigating collaboration and division of labor in biomedical research using partial alphabetical authorship.

    PubMed

    Mongeon, Philippe; Smith, Elise; Joyal, Bruno; Larivière, Vincent

    2017-01-01

    Contemporary biomedical research is performed by increasingly large teams. Consequently, an increasingly large number of individuals are being listed as authors in the bylines, which complicates the proper attribution of credit and responsibility to individual authors. Typically, more importance is given to the first and last authors, while it is assumed that the others (the middle authors) have made smaller contributions. However, this may not properly reflect the actual division of labor because some authors other than the first and last may have made major contributions. In practice, research teams may differentiate the main contributors from the rest by using partial alphabetical authorship (i.e., by listing middle authors alphabetically, while maintaining a contribution-based order for more substantial contributions). In this paper, we use partial alphabetical authorship to divide the authors of all biomedical articles in the Web of Science published over the 1980-2015 period in three groups: primary authors, middle authors, and supervisory authors. We operationalize the concept of middle author as those who are listed in alphabetical order in the middle of an authors' list. Primary and supervisory authors are those listed before and after the alphabetical sequence, respectively. We show that alphabetical ordering of middle authors is frequent in biomedical research, and that the prevalence of this practice is positively correlated with the number of authors in the bylines. We also find that, for articles with 7 or more authors, the average proportion of primary, middle and supervisory authors is independent of the team size, more than half of the authors being middle authors. This suggests that growth in authors lists are not due to an increase in secondary contributions (or middle authors) but, rather, in equivalent increases of all types of roles and contributions (including many primary authors and many supervisory authors). Nevertheless, we show that the

  10. MOLECULAR ANALYSIS OF HUMAN SPERMATOZOA: POTENTIAL FOR INFERTILITY RESEARCH

    EPA Science Inventory

    Gordon Research Conference: Mammalian Gametogenesis and Embryogenesis
    New London, CT, July 1-6, 2000

    Molecular Analysis of Human Spermatozoa:
    Potential for Infertility Research

    David Miller 1, David Dix2, Robert Reid 3, Stephen A Krawetz 3
    1Reproductive ...

  11. MOLECULAR ANALYSIS OF HUMAN SPERMATOZOA: POTENTIAL FOR INFERTILITY RESEARCH

    EPA Science Inventory

    Gordon Research Conference: Mammalian Gametogenesis and Embryogenesis
    New London, CT, July 1-6, 2000

    Molecular Analysis of Human Spermatozoa:
    Potential for Infertility Research

    David Miller 1, David Dix2, Robert Reid 3, Stephen A Krawetz 3
    1Reproductive ...

  12. Science Education Outreach Activities in the Fusion Energy Division of UCSD’s Center for Energy Research*

    NASA Astrophysics Data System (ADS)

    Moyer, R. A.; Stewart, P.; van Fleet, J.

    2001-10-01

    Since 1995, the Fusion Energy Division of the Center for Energy Research at UCSD has been engaged in a variety of volunteer activities in science education outreach. FED staff have developed demonstration tools on energy and plasma science which are used effectively with middle and high school students as well as teacher/student groups at: the APS DPP Plasma Expos and the San Diego Co. Educational Technology Fair. These demonstration tools have proven effective in communicating with elementary students at community science and technology exhibits at the Reuban H. Fleet Science Center (San Diego) and in elementary school classes. UCSD scientists have also participated as team members of the GA Fusion Group’s programs: "Scientist in the Classroom" , and the two Plasma Institutes for in-service science teachers. In the coming year, we plan to: 1) expand the "Scientist in the Classroom" to home-schooled children in San Diego; 2) participate in local elementary school Family Science Nights; and 3) assist in training a new group of future San Diego Unified School District ninth grade physics teachers.

  13. MIPortal: a high capacity server for molecular imaging research.

    PubMed

    Pivovarov, Misha; Bhandary, Gokul; Mahmood, Umar; Zahlmann, Gudrun; Naraghi, Mohammad; Weissleder, Ralph

    2005-01-01

    The introduction of novel molecular tools in research and clinical medicine has created a need for more refined information management systems. This article describes the design and implementation of such a new information platform: the Molecular Imaging Portal (MIPortal). The platform was created to organize, archive, and rapidly retrieve large datasets using Web-based browsers as access points. The system has been implemented in a heterogeneous, academic research environment serving Macintosh, Unix, and Microsoft Windows clients and has been shown to be extraordinarily robust and versatile. In addition, it has served as a useful tool for clinical trials and collaborative multi-institutional small-animal imaging research.

  14. [Research progress on molecular ecology of Sciurus vulgaris].

    PubMed

    Liu, Zhu; Tian, Xin-min; Chen, Huan; Guo, Hui-yan; Jin, Jian-li; Zhang, Xiao-jun

    2015-03-01

    Today, the main threats for Sciurus vulgaris are illegal hunting, deforestation, and subsequent population fragmentation, combined with interspecific competition from S. carolinensis in some regions of Europe, which has led to a sharp reduction in the number of population. S. vulgaris has been listed as Near Threatened IUCN Red List and included in key protected wild animals in Jilin Province, China. The molecular ecology of S. vulgaris is developing rapidly with the rapid development of molecular biology methods. In particular, the research of mtDNA fragments and the application squirrel study microsatellite loci has further promoted the molecular ecology of S. vulgaris. In this study, the molecular phylogeny, the genetic diversity and the molecular phylogeography involving the molecular ecology of S. vulgaris were reviewed. Four areas for the future development in molecular ecology of S. vulgaris were proposed: 1) to further explore the molecular phylogeny relationship between S. vulgaris and S. lis; 2) the comparative analysis of the genetic diversity of S. vulgaris for continuous populations, isolated populations and metapopulation; 3) the analysis of molecular phylogeography of S. vulgaris based on other markers of nuclear; 4) to explore whether there existed the quaternary glacial refuge in Asia.

  15. Report: Results of Technical Network Vulnerability Assessment: EPA’s National Health & Environment Effects Research Laboratory, Western Ecology Division

    EPA Pesticide Factsheets

    Report #11-P-0429, August 3, 2011. Vulnerability testing of EPA’s NHEERL Western Ecology Division network conducted in March 2011 identified Internet Protocol addresses with numerous high-risk and medium-risk vulnerabilities.

  16. Bibliometric analysis of original molecular biology research in anaesthesia.

    PubMed

    Schreiber, K; Girard, T; Kindler, C H

    2004-10-01

    Molecular biology has expanded the horizons of anaesthesia during the last 20 years and has led to an increase of basic science articles that are published in the specialised anaesthetic journals or originate in anaesthetic institutions. We searched for and analysed the specific features, such as year of publication, publishing journal, and country of origin, of all such molecular biology articles stored in the MEDLINE database during the period 1986-2002. We identified 1265 original articles that used molecular biology techniques; 223 (18%) of these articles were published in anaesthetic journals and 1042 (82%) articles in 556 other biomedical journals. While in the late 1980s only a few molecular biology articles were published each year by anaesthetic institutions, worldwide this number reached approximately 200 basic science articles by the end of 2002. The USA clearly dominates the field of anaesthesia with respect to molecular biology research with 839 (66%) such articles.

  17. Pilotless Aircraft Research Division

    NASA Technical Reports Server (NTRS)

    1950-01-01

    Sperry Model 10 Velocimeter, Doppler radar at Wallops Island with trackers P.R. Mears and J. Quillen. Metallic ears pointed to the heavens, this radio tracking device kept tabs on Wallops rocket firings. Joseph Shortal has described this Doppler radar as follows: 'The Doppler radar was a genuine asset to PARD; it made possible the direct determination of velocity and allowed the measurement of drag for such simple models as the RM-2 and RM-5 types. Doppler radars were used in every launching from Wallops.' 'In cooperation with the Army's Aberdeen Proving Ground, specifications for a more powerful Doppler radar were prepared. A 150-watt radar which its manufacturer, Sperry Gyroscope Corp., called the Model 10 Velocimeter, was purchased. This radar was mounted on a SCR-547 trailer, which led Langley men to call it the TPS-547 radar for some time. This radar had a range of approximately five miles and was the first of a series of this type in use at Wallops for many years.' 'One operator directed the dishes toward the target in azimuth while the other operator controlled the elevation (The fact that two operators with independent gun sights and earphones could coordinate their efforts in this fashion surprised many 'experts'.). The Doppler radars were always located near the launcher and the operators normally served in the dual capacity of rocket technicians. After the Velocimeter was placed in operation, the TPS-5 radars were no longer used.' Photograph published in Winds of Change, a 75th Anniversary NASA publication (page 74), by James Schultz. Published in Joseph A. Shortal, History of Wallops Station: Origins and Activities Through 1949, (Wallops Island, VA: National Aeronautics and Space Administration, Wallops Station, nd), Comment Edition. Photograph published in A New Dimension; Wallops Island Flight Test Range: The First Fifteen Years by Joseph Adams Shortal. A NASA publication (page 99).

  18. Pilotless Aircraft Research Division

    NASA Technical Reports Server (NTRS)

    1945-01-01

    The launching of the first rocket at the NACA's Wallop's Island Facility on June 27, 1945. Joseph Shortal described this launch as follows: 'The initial operations on June 27, 1945 on Wallops were to check the tracking station location and operation, check the use of CW (Doppler radar for measuring velocities of missiles and to gain experience with actual rockets. Five 3.25 inch rockets were fired at 39.4 elevation angle, and one each at 33.7, 29.3, and 21.5. All were fired in a direction parallel to the beach to simulate the first Tiamat missile launching. Four of the eight rockets were tracked satisfactorily by the SCR-584 radar located at the mainland tracking station 2 and a strong signal was obtained on the CW radar. As [Ray W.] Hooker stated in his official report on the operations, 'In general, the operation was successful.' [Germain S.] Brown, in his diary expressed it this way: 'Hooker and gang arrived by B24 at 10:30. Went to Island and launched about eight rockets with satisfactory results. Lt. Rucker and 3 Navy enlisted men assisted us.' 'For this operation the rockets and the ordnance personnel were supplied by the Patuxent Naval Air Station. Navy Buaer had established a special project to cover this cooperation with NACA.' Excerpts from Joseph Shortal's history of Wallops Station.

  19. Multi-modality molecular imaging for gastric cancer research

    NASA Astrophysics Data System (ADS)

    Liang, Jimin; Chen, Xueli; Liu, Junting; Hu, Hao; Qu, Xiaochao; Wang, Fu; Nie, Yongzhan

    2011-12-01

    Because of the ability of integrating the strengths of different modalities and providing fully integrated information, multi-modality molecular imaging techniques provide an excellent solution to detecting and diagnosing earlier cancer, which remains difficult to achieve by using the existing techniques. In this paper, we present an overview of our research efforts on the development of the optical imaging-centric multi-modality molecular imaging platform, including the development of the imaging system, reconstruction algorithms and preclinical biomedical applications. Primary biomedical results show that the developed optical imaging-centric multi-modality molecular imaging platform may provide great potential in the preclinical biomedical applications and future clinical translation.

  20. Translational research of optical molecular imaging for personalized medicine.

    PubMed

    Qin, C; Ma, X; Tian, J

    2013-12-01

    In the medical imaging field, molecular imaging is a rapidly developing discipline and forms many imaging modalities, providing us effective tools to visualize, characterize, and measure molecular and cellular mechanisms in complex biological processes of living organisms, which can deepen our understanding of biology and accelerate preclinical research including cancer study and medicine discovery. Among many molecular imaging modalities, although the penetration depth of optical imaging and the approved optical probes used for clinics are limited, it has evolved considerably and has seen spectacular advances in basic biomedical research and new drug development. With the completion of human genome sequencing and the emergence of personalized medicine, the specific drug should be matched to not only the right disease but also to the right person, and optical molecular imaging should serve as a strong adjunct to develop personalized medicine by finding the optimal drug based on an individual's proteome and genome. In this process, the computational methodology and imaging system as well as the biomedical application regarding optical molecular imaging will play a crucial role. This review will focus on recent typical translational studies of optical molecular imaging for personalized medicine followed by a concise introduction. Finally, the current challenges and the future development of optical molecular imaging are given according to the understanding of the authors, and the review is then concluded.

  1. [Progress in researches of molecular mechanism of schistosome cercariae infection].

    PubMed

    Du, Xiaofeng; Ju, Chuan; Hu, Wei

    2013-12-01

    Schistosome cercariae must penetrate skin as an initial step to successfully infect the final host. Proteolytic enzymes secreted from the acetabular glands of cercariae contribute significantly to the invasion process. Nowadays, the researches of molecular mechanism of schistosome infection mainly focus on the cercarial secretions including serine protease and cysteine protease. Previous researches already showed that Schistosoma mansoni penetrates the skin mainly depend on cercarial elastease secreted by cercariae while Schistosoma japonicum penetrates the skin chiefly by cathepsin B2. The illustration of molecular mechanism of schistosome cecariae infection will accelerate the identification of novel vaccines and drug targets.

  2. [Division of regulatory cellular systems (Lvov)].

    PubMed

    Kusen', S I

    1995-01-01

    Two departments of the A. V. Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine were founded in 1969 in Lviv. These were: the Department of Biochemistry of Cell Differentiation headed by Professor S. I. Kusen and Department of Regulation of Cellular Synthesis of Low Molecular Weight Compounds headed by Professor G. M. Shavlovsky. The Lviv Division of the A. V. Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine with Professor S. I. Kusen as its chief, was founded in 1974 on the basis of these departments and the Laboratory of Modelling of Regulatory Cellular Systems headed by Professor M. P. Derkach. The above mentioned laboratory which was not the structural unit obtained the status of Structural Laboratory of Cellular Biophysics in 1982 and was headed by O. A. Goida, Candidate of biological sciences. From 1983 the Laboratory of Correcting Therapy of Malignant Tumors and Hemoblastoses at the Institute of Molecular Biology and Genetics, Academy of Sciences of Ukraine (Chief--S. V. Ivasivka, Candidate of medical sciences) was included in the structure of the Division. That Laboratory was soon transformed into the Department of Carbohydrate Metabolism Regulation headed by Professor I. D. Holovatsky. In 1988 this Department was renamed into the Department of Glycoprotein Biochemistry and headed by M. D. Lutsik, Doctor of biological sciences. In 1982 one more Laboratory of Biochemical Genetics was founded at the Department of Regulation of Cellular Synthesis of Low Molecular Weight Compounds, in 1988 it was transformed into the Department of Biochemical Genetics (Chief--Professor A. A. Sibirny). In 1989 the Laboratory of Anion Transport was taken from A. V. Palladin Institute of Biochemistry, Academy of Sciences of Ukraine to Lviv Division of this Institute. This laboratory was headed by Professor M. M. Veliky. One more reorganization in the Division structure took place in 1994. The Department of

  3. IFLA General Conference, 1990. Division of General Research Libraries: Open Forum; Section of National Libraries; Section of University Libraries and Other General Research Libraries; Section of Parliamentary Libraries. Booklet 1.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    The 16 reports in this collection were presented at an open forum on research libraries and meetings of three more specialized sections: (1) "Nature and Purpose of the Division of General Research Libraries" (Ernst Kohl); (2) "Objectives and Goals of the Section of Parliamentary Libraries" (Ernst Kohl); (3) "The IFLA…

  4. IFLA General Conference, 1990. Division of General Research Libraries: Open Forum; Section of National Libraries; Section of University Libraries and Other General Research Libraries; Section of Parliamentary Libraries. Booklet 1.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    The 16 reports in this collection were presented at an open forum on research libraries and meetings of three more specialized sections: (1) "Nature and Purpose of the Division of General Research Libraries" (Ernst Kohl); (2) "Objectives and Goals of the Section of Parliamentary Libraries" (Ernst Kohl); (3) "The IFLA…

  5. Application of molecular techniques on heterotrophic hydrogen production research.

    PubMed

    Li, R Y; Zhang, T; Fang, H H P

    2011-09-01

    This paper reviews the application of molecular techniques in heterotrophic hydrogen production studies. Commonly used molecular techniques are introduced briefly first, including cloning-sequencing after polymerase chain reaction (PCR), denaturing gradient gel electrophoresis (DGGE), terminal-restriction fragment length polymorphism (T-RFLP), fluorescence in situ hybridization (FISH) and quantitative real-time PCR. Application of the molecular techniques in heterotrophic hydrogen production studies are discussed in details, focusing on identification of new isolates for hydrogen production, characterization of microbial compositions in bioreactors, monitoring microbial diversity variation, visualization of microbial distribution in hydrogen-producing granular sludge, and quantification of various microbial populations. Some significant findings in recent hydrogen production studies with the application of molecular techniques are discussed, followed by a research outlook of the heterotrophic biohydrogen field.

  6. Division i: Fundamental Astronomy

    NASA Astrophysics Data System (ADS)

    McCarthy, Dennis D.; Klioner, Sergei A.; Vondrák, Jan; Evans, Dafydd Wyn; Hohenkerk, Catherine Y.; Hosokawa, Mizuhiko; Huang, Cheng-Li; Kaplan, George H.; Knežević, Zoran; Manchester, Richard N.; Morbidelli, Alessandro; Petit, Gérard; Schuh, Harald; Soffel, Michael H.; Zacharias, Norbert

    2012-04-01

    The goal of the division is to address the scientific issues that were developed at the 2009 IAU General Assembly in Rio de Janeiro. These are:•Astronomical constants-Gaussian gravitational constant, Astronomical Unit, GMSun, geodesic precession-nutation•Astronomical software•Solar System Ephemerides-Pulsar research-Comparison of dynamical reference frames•Future Optical Reference Frame•Future Radio Reference Frame•Exoplanets-Detection-Dynamics•Predictions of Earth orientation•Units of measurements for astronomical quantities in relativistic context•Astronomical units in the relativistic framework•Time-dependent ecliptic in the GCRS•Asteroid masses•Review of space missions•Detection of gravitational waves•VLBI on the Moon•Real time electronic access to UT1-UTCIn pursuit of these goals Division I members have made significant scientific and organizational progress, and are organizing a Joint Discussion on Space-Time Reference Systems for Future Research at the 2012 IAU General Assembly. The details of Division activities and references are provided in the individual Commission and Working Group reports in this volume. A comprehensive list of references related to the work of the Division is available at the IAU Division I website at http://maia.usno.navy.mil/iaudiv1/.

  7. Physics Division annual report, April 1, 1993--March 31, 1994

    SciTech Connect

    Thayer, K.J.; Henning, W.F.

    1994-08-01

    This is the Argonne National Laboratory Physics Division Annual Report for the period April 1, 1993 to March 31, 1994. It summarizes work done in a number of different fields, both on site, and at other facilities. Chapters describe heavy ion nuclear physics research, operation and development of the ATLAS accelerator, medium-energy nuclear physics research, theoretical physics, and atomic and molecular physics research.

  8. In focus: molecular and cell biology research in China.

    PubMed

    Yao, Xuebiao; Li, Dangsheng; Pei, Gang

    2013-09-01

    An interactive, intellectual environment with good funding opportunities is essential for the development and success of basic research. The fast-growing economy and investment in science, together with a visionary plan, have attracted foreign scholars to work in China, motivated world-class Chinese scientists to return and strengthened the country's international collaborations. As a result, molecular and cell biology research in China has evolved rapidly over the past decade.

  9. Understanding Microbial Divisions of Labor

    PubMed Central

    Zhang, Zheren; Claessen, Dennis; Rozen, Daniel E.

    2016-01-01

    Divisions of labor are ubiquitous in nature and can be found at nearly every level of biological organization, from the individuals of a shared society to the cells of a single multicellular organism. Many different types of microbes have also evolved a division of labor among its colony members. Here we review several examples of microbial divisions of labor, including cases from both multicellular and unicellular microbes. We first discuss evolutionary arguments, derived from kin selection, that allow divisions of labor to be maintained in the face of non-cooperative cheater cells. Next we examine the widespread natural variation within species in their expression of divisions of labor and compare this to the idea of optimal caste ratios in social insects. We highlight gaps in our understanding of microbial caste ratios and argue for a shift in emphasis from understanding the maintenance of divisions of labor, generally, to instead focusing on its specific ecological benefits for microbial genotypes and colonies. Thus, in addition to the canonical divisions of labor between, e.g., reproductive and vegetative tasks, we may also anticipate divisions of labor to evolve to reduce the costly production of secondary metabolites or secreted enzymes, ideas we consider in the context of streptomycetes. The study of microbial divisions of labor offers opportunities for new experimental and molecular insights across both well-studied and novel model systems. PMID:28066387

  10. Progress in nucleic acid research and molecular biology

    SciTech Connect

    Cohn, W.E. . Biology Div.); Moldave, K. )

    1989-01-01

    This book contain the proceedings on progress in nucleic acid research and molecular biology. Topics covered include: polynucleotide-protein cross-links induced by ultraviolet light and their use for structural investigation of nucleoproteins; left-handed Z-DNA and genetic recombination, and structure and function of signal recognition particle RNA.

  11. Harnessing the crowd to accelerate molecular medicine research.

    PubMed

    Smith, Robert J; Merchant, Raina M

    2015-07-01

    Crowdsourcing presents a novel approach to solving complex problems within molecular medicine. By leveraging the expertise of fellow scientists across the globe, broadcasting to and engaging the public for idea generation, harnessing a scalable workforce for quick data management, and fundraising for research endeavors, crowdsourcing creates novel opportunities for accelerating scientific progress.

  12. | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  13. | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  14. PAST AND PRESENT: 50 YEARS OF AIR QUALITY MODELING RESEARCH AND ITS APPLICATIONS BY THE NOAA ATMOSPHERIC SCIENCES MODELING DIVISION

    EPA Science Inventory

    The NOAA Atmospheric Sciences Modeling Division (ASMD) celebrated its Golden Jubilee in September 2005. The partnership between NOAA and EPA began when the Air Pollution Unit of the Public Health Service, which later became part of the EPA, requested the Weather Bureau provide ...

  15. PAST AND PRESENT: 50 YEARS OF AIR QUALITY MODELING RESEARCH AND ITS APPLICATIONS BY THE NOAA ATMOSPHERIC SCIENCES MODELING DIVISION

    EPA Science Inventory

    The NOAA Atmospheric Sciences Modeling Division (ASMD) celebrated its Golden Jubilee in September 2005. The partnership between NOAA and EPA began when the Air Pollution Unit of the Public Health Service, which later became part of the EPA, requested the Weather Bureau provide ...

  16. Substance Abuse Treatment and Arrests: Analyses from Washington State. DSHS Research and Data Analysis Division Fact Sheet.

    ERIC Educational Resources Information Center

    Luchansky, Bill; He, Lijian; Longhi, Dario

    This fact sheet uses treatment records from the Division of Alcohol and Substance Abuse, in conjunction with records from the Washington State Patrol to examine the criminal justice involvement of persons before and after treatment for substance abuse. The study population was 10,284 clients between the ages of 18 and 64, who began and ended…

  17. Fundamentals of quality assessment of molecular amplification methods in clinical diagnostics. International Federation of Clinical Chemistry Scientific Division Committee on Molecular Biology Techniques.

    PubMed

    Neumaier, M; Braun, A; Wagener, C

    1998-01-01

    The increasing interest in molecular biology diagnostics is a result of the tremendous gain of scientific knowledge in genetics, made possible especially since the introduction of amplification techniques. High expectations have been placed on genetic testing, and the number of laboratories now using the relevant technology is rapidly increasing--resulting in an obvious need for standardization and definition of laboratory organization. This communication is an effort towards that end. We address aspects that should be considered when structuring a new molecular diagnostic laboratory, and we discuss individual preanalytical and analytical procedures, from sampling to evaluation of assay results. In addition, different means of controlling contamination are discussed. Because the methodology is in constant change, no general standards can be defined. Accordingly, this publication is intended to serve as a recommendation for good laboratory practice and internal quality control and as a guide to troubleshooting, primarily in amplification techniques.

  18. A New Paradigm for Mentored Undergraduate Research in Molecular Microbiology

    PubMed Central

    2007-01-01

    Science educators agree that an undergraduate research experience is critical for students who are considering graduate school or research careers. The process of researching a topic in the primary literature, designing experiments, implementing those experiments, and analyzing the results is essential in developing the analytical skills necessary to become a true scientist. Because training undergraduates who will only be in the laboratory for a short period is time consuming for faculty mentors, many students are unable to find appropriate research opportunities. We hypothesized that we could effectively mentor several students simultaneously, using a method that is a hybrid of traditional undergraduate research and a traditional laboratory course. This article describes a paradigm for mentored undergraduate research in molecular microbiology where students have ownership of their individual projects, but the projects are done in parallel, enabling the faculty mentor to guide multiple students efficiently. PMID:18056305

  19. BALLView: a tool for research and education in molecular modeling.

    PubMed

    Moll, Andreas; Hildebrandt, Andreas; Lenhof, Hans-Peter; Kohlbacher, Oliver

    2006-02-01

    We present BALLView, a molecular viewer and modeling tool. It combines state-of-the-art visualization capabilities with powerful modeling functionality including implementations of force field methods and continuum electrostatics models. BALLView is a versatile and extensible tool for research in structural bioinformatics and molecular modeling. Furthermore, the convenient and intuitive graphical user interface offers novice users direct access to the full functionality, rendering it ideal for teaching. Through an interface to the object-oriented scripting language Python it is easily extensible.

  20. Lightning Talks 2015: Theoretical Division

    SciTech Connect

    Shlachter, Jack S.

    2015-11-25

    This document is a compilation of slides from a number of student presentations given to LANL Theoretical Division members. The subjects cover the range of activities of the Division, including plasma physics, environmental issues, materials research, bacterial resistance to antibiotics, and computational methods.

  1. Chemical Technology Division annual technical report, 1994

    SciTech Connect

    1995-06-01

    Highlights of the Chemical Technology (CMT) Division`s activities during 1994 are presented. In this period, CMT conducted research and development in the following areas: (1) electrochemical technology, including advanced batteries and fuel cells; (2) technology for fluidized-bed combustion; (3) methods for treatment of hazardous waste and mixed hazardous/radioactive waste; (4) the reaction of nuclear waste glass and spent fuel under conditions expected for an unsaturated repository; (5) processes for separating and recovering transuranic elements from waste streams, concentrating radioactive waste streams with advanced evaporator technology, and producing {sup 99}Mo from low-enriched uranium for medical applications; (6) electrometallurgical treatment of the many different types of spent nuclear fuel in storage at Department of Energy sites; and (8) physical chemistry of selected materials in environments simulating those of fission and fusion energy systems. The Division also conducts basic research in catalytic chemistry associated with molecular energy resources and novel ceramic precursors; materials chemistry of superconducting oxides, electrified metal/solution interfaces, molecular sieve structures, and impurities in scrap copper and steel; and the geochemical processes involved in mineral/fluid interfaces and water-rock interactions occurring in active hydrothermal systems. In addition, the Analytical Chemistry Laboratory in CMT provides a broad range of analytical chemistry support services to the technical programs at Argonne National Laboratory (ANL).

  2. [Research progress on molecular genetics of forest musk deer].

    PubMed

    Jie, Hang; Zheng, Cheng-li; Wang, Jian-ming; Feng, Xiao-lan; Zeng, De-jun; Zhao, Gui-jun

    2015-11-01

    Forest musk deer is one of the large-scale farming musk deer animals with the largest population at the same time. The male musk deer can secrete valuable medicines, which has high medicinal and economic value. Due to the loss of habitat and indiscriminate hunting, the numbers of wild population specie and the distribution have been drastically reduced. Therefore, in-depth understanding of the molecular genetics progress of forest musk deer will pave a way for musk deer protection and breeding. In this review, the progress associated with the molecular marker, genetic classification, artificial breeding, musk secretion and disease in past decades were reviewed, in order to provide a theoretical basis for subsequent molecular genetic researches in forest musk deer.

  3. Using a Research-based Approach to Transform Upper-division Courses in Classical and Quantum Mechanics and E&M

    NASA Astrophysics Data System (ADS)

    Pollock, Steven

    2013-04-01

    At most universities, including the University of Colorado, upper-division physics courses are taught using a traditional lecture approach that does not make use of many of the instructional techniques that have been found to improve student learning at the introductory level. We are transforming several upper-division courses using principles of active engagement and learning theory, guided by the results of observations, interviews, and analysis of student work at CU and elsewhere. In this talk I outline these transformations, including the development of faculty consensus learning goals, clicker questions, tutorials, modified homeworks, and more. We present evidence of the effectiveness of these transformations relative to traditional courses, based on student grades, interviews, and through research-based assessments of student conceptual mastery and student attitudes. Our results suggest that many of the tools that have been effective in introductory courses are effective for our majors, and that further research is warranted in the upper-division environment. (See www.colorado.edu/sei/departments/physics.htm for materials)

  4. Investigative cases and student outcomes in an upper-division cell and molecular biology laboratory course at a minority-serving institution.

    PubMed

    Knight, Jonathan D; Fulop, Rebecca M; Márquez-Magaña, Leticia; Tanner, Kimberly D

    2008-01-01

    Active-learning strategies are increasingly being integrated into college-level science courses to make material more accessible to all students and to improve learning outcomes. One active-learning pedagogy, case-based learning (CBL), was developed as a way to both enhance engagement in the material and to accommodate diverse learning styles. Yet, adoption of CBL approaches in undergraduate biology courses has been piecemeal, in part because of the perceived investment of time required. Furthermore, few CBL lesson plans have been developed specifically for upper-division laboratory courses. Here, we describe four cases that we developed and implemented for a senior cell and molecular biology laboratory course at San Francisco State University, a minority-serving institution. To evaluate the effectiveness of these modules, we used both written and verbal assessments to gauge learning outcomes and attitudinal responses of students over two semesters. Students responded positively to the new approach and seemed to meet the learning goals for the course. Most said they would take a course using CBL again. These case modules are readily adaptable to a variety of classroom settings.

  5. Physics division annual report 2006.

    SciTech Connect

    Glover, J.; Physics

    2008-02-28

    This report highlights the activities of the Physics Division of Argonne National Laboratory in 2006. The Division's programs include the operation as a national user facility of ATLAS, the Argonne Tandem Linear Accelerator System, research in nuclear structure and reactions, nuclear astrophysics, nuclear theory, investigations in medium-energy nuclear physics as well as research and development in accelerator technology. The mission of nuclear physics is to understand the origin, evolution and structure of baryonic matter in the universe--the core of matter, the fuel of stars, and the basic constituent of life itself. The Division's research focuses on innovative new ways to address this mission.

  6. Structural dynamics division research and technology accomplishments for F.Y. 1991 and plans for F.Y. 1992

    NASA Technical Reports Server (NTRS)

    Wynne, Eleanor C.

    1992-01-01

    The work under each technical area is described in terms of highlights of accomplishments during the past year and highlights of plans for the current year as they relate to 5 year plans for each technical area. This information will be useful in program coordination with other government organizations and industry in areas of mutual interest. The structural dynamics division consist of the following branches: configuration aeroelasticity; unsteady aerodynamics; aeroservoelasticity; landing and impact dynamics; and spacecraft dynamics.

  7. Chemical and Laser Sciences Division annual report 1989

    SciTech Connect

    Haines, N.

    1990-06-01

    The Chemical and Laser Sciences Division Annual Report includes articles describing representative research and development activities within the Division, as well as major programs to which the Division makes significant contributions.

  8. 2004 Atomic and Molecular Interactions Gordon Research Conference

    SciTech Connect

    Dr. Paul J. Dagdigian

    2004-10-25

    The 2004 Gordon Research Conference on Atomic and Molecular Interactions was held July 11-16 at Colby-Sawyer College, New London, New Hampshire. This latest edition in a long-standing conference series featured invited talks and contributed poster papers on dynamics and intermolecular interactions in a variety of environments, ranging from the gas phase through surfaces and condensed media. A total of 90 conferees participated in the conference.

  9. IFLA General Conference, 1989. Division of Education and Research. Section on Education and Training; Round Table on Library History; Round Table on Research in Reading; Round Table on Continuing Professional Education. Booklet 70.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    There are 10 papers in this collection from the Division of Education and Research: (1) "The Importance of Basic Training in Marketing for Librarians and Information Professionals" (French and English versions; Rejean Savard); (2) "Information Management Education: Some Interdisciplinary Approaches" (Marianne Broadbent); (3) "Educational…

  10. Proceedings of Selected Research Paper Presentations at the 1980 Convention of the Association for Educational Communications and Technology and Sponsored by the Research and Theory Division (Denver, CO, April 21-24, 1980).

    ERIC Educational Resources Information Center

    Simonson, Michael R., Ed.; Rohner, Daniel, Ed.

    1980-01-01

    The 31 papers in this collection represent approximately 35 percent of the manuscripts which were submitted for consideration to the Research and Theory Division of the Association for Educational Communications and Technology (AECT) for presentation at the 1980 AECT convention. All papers were subjected to a blind reviewing process and the ones…

  11. IFLA General Conference, 1989. Division of Education and Research. Section on Education and Training; Round Table on Library History; Round Table on Research in Reading; Round Table on Continuing Professional Education. Booklet 70.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    There are 10 papers in this collection from the Division of Education and Research: (1) "The Importance of Basic Training in Marketing for Librarians and Information Professionals" (French and English versions; Rejean Savard); (2) "Information Management Education: Some Interdisciplinary Approaches" (Marianne Broadbent); (3) "Educational…

  12. Forty years of the Institute for Nuclear Research (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 22 December 2010)

    NASA Astrophysics Data System (ADS)

    2011-09-01

    On 22 December 2010, the scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS), devoted to the 40th anniversary of the Institute for Nuclear Research, RAS, was held at the Institute for Nuclear Research, RAS in Troitsk. The agenda of the session announced on the website www.gpad.ac.ru of the RAS Physical Sciences Division listed the following reports: (1) Matveev V A (Institute for Nuclear Research, RAS, Moscow) "Introductory word"; (2) Gavrin V N (Institute for Nuclear Research, RAS, Moscow) "Contribution of the SAGE results to the understanding of solar physics and neutrino physics"; (3) Domogatsky G V (Institute for Nuclear Research, RAS, Moscow) "Baikal neutrino experiment"; (4) Tkachev I I (Institute for Nuclear Research, RAS, Moscow) "Observation of the Greisen - Zatsepin - Kuz'min effect at the Telescope Array Observatory"; (5) Kudenko Yu G (Institute for Nuclear Research, RAS, Moscow) "Neutrino T2K experiment: the first results"; (6) Sadykov R A (Institute for Nuclear Research, RAS, Moscow) "Fields of study of condensed media at the neutron facility at the INR, RAS"; (7) Zhuikov B L (Institute for Nuclear Research, RAS, Moscow) "Production of isotopes at the INR, RAS: reality and prospects".The papers written on the base of reports 1-5 and 7 are published below. In addition, the paper "High-power diode-pumped alkali lasers" by A M Shalagin is published. The paper is based on the report presented at the scientific session of the General Assembly of the Physical Sciences Division, RAS (13 December 2010) devoted to the 50th anniversary of the laser, the main materials of the session having been published in Usp. Fiz. Nauk 181 (8) 867 (2011) [Phys. Usp. 54 837 (2011)]. • Institute for Nuclear Research of the Russian Academy of Sciences turns 40, V A Matveev Physics-Uspekhi, 2011, Volume 54, Number 9, Pages 939-940 • The Russian-American gallium experiment SAGE, V N Gavrin Physics-Uspekhi, 2011, Volume 54, Number 9

  13. [Clinical implications of molecular genetic research in otorhinolaryngology].

    PubMed

    Gürtler, N

    2003-08-01

    Molecular-genetic research in Otolaryngology has seen a rapid advancement during the last ten years, especially in the fields of otology and head and neck tumors. The results of this basic research have now started to be implemented in the clinic. In otology the understanding of auditive function has dramatically improved. The syndromic and non-syndromic forms of hereditary hearing impairment can be subdivided into their underlying genetic defects, as more and more genes are identified. Diagnostic of syndromic hearing loss has been improved and can be done earlier. But the molecular-genetic analysis is still time-consuming and difficult. Currently, in our clinic, only patients with suspected Pendred-syndrome, representing the most frequent syndrome with hearing impairment, undergo a routine search for mutation detection in the corresponding gene SLC26A4. A multitude of genes and mutations are seen in the non-syndromic forms of hereditary hearing impairment. The gene gap-junction-protein beta2, encoding connexin 26, is encountered most frequently. Its prevalence in Switzerland is high with about 20% in the non-syndromic group. A molecular-genetic analysis of connexin 26 is offered in cases of congenital hearing loss. Another analysis, which has been implemented in the clinic, is the sequencing of Wolfram-syndrome gene 1 in familial low-frequency hearing loss. This gene seems to be involved in the majority of families with this type of hearing loss. Gene therapy for hearing loss is currently not an option in the clinical field. The different steps in carcinogenesis of head and neck cancer have further been elucidated by molecular-genetic research. Clinical applications are the establishment of risk-profiles for tumor-development and defining prognostic markers as well as the development of new treatment strategies based on genetic therapy.

  14. Molecular nutrition research: the modern way of performing nutritional science.

    PubMed

    Norheim, Frode; Gjelstad, Ingrid Merethe Fange; Hjorth, Marit; Vinknes, Kathrine J; Langleite, Torgrim M; Holen, Torgeir; Jensen, Jørgen; Dalen, Knut Tomas; Karlsen, Anette S; Kielland, Anders; Rustan, Arild C; Drevon, Christian A

    2012-12-03

    In spite of amazing progress in food supply and nutritional science, and a striking increase in life expectancy of approximately 2.5 months per year in many countries during the previous 150 years, modern nutritional research has a great potential of still contributing to improved health for future generations, granted that the revolutions in molecular and systems technologies are applied to nutritional questions. Descriptive and mechanistic studies using state of the art epidemiology, food intake registration, genomics with single nucleotide polymorphisms (SNPs) and epigenomics, transcriptomics, proteomics, metabolomics, advanced biostatistics, imaging, calorimetry, cell biology, challenge tests (meals, exercise, etc.), and integration of all data by systems biology, will provide insight on a much higher level than today in a field we may name molecular nutrition research. To take advantage of all the new technologies scientists should develop international collaboration and gather data in large open access databases like the suggested Nutritional Phenotype database (dbNP). This collaboration will promote standardization of procedures (SOP), and provide a possibility to use collected data in future research projects. The ultimate goals of future nutritional research are to understand the detailed mechanisms of action for how nutrients/foods interact with the body and thereby enhance health and treat diet-related diseases.

  15. Chemistry-nuclear chemistry division. Progress report, October 1979-September 1980

    SciTech Connect

    Ryan, R.R.

    1981-05-01

    This report presents the research and development programs pursued by the Chemistry-Nuclear Chemistry Division of the Los Alamos National Laboratory. Topics covered include advanced analytical methods, atmospheric chemistry and transport, biochemistry, biomedical research, element migration and fixation, inorganic chemistry, isotope separation and analysis, atomic and molecular collisions, molecular spectroscopy, muonic x rays, nuclear cosmochemistry, nuclear structure and reactions, radiochemical separations, theoretical chemistry, and unclassified weapons research.

  16. Argonne National Laboratory, High Energy Physics Division, semiannual report of research activities, July 1, 1989--December 31, 1989

    SciTech Connect

    Not Available

    1989-01-01

    This report discusses research being conducted at the Argonne National Laboratory in the following areas: Experimental High Energy Physics; Theoretical High Energy Physics; Experimental Facilities Research; Accelerator Research and Development; and SSC Detector Research and Development.

  17. Long Divisions

    NASA Image and Video Library

    2016-08-08

    The shadow of Saturn on the rings, which stretched across all of the rings earlier in Cassini's mission (see PIA08362), now barely makes it past the Cassini division. The changing length of the shadow marks the passing of the seasons on Saturn. As the planet nears its northern-hemisphere solstice in May 2017, the shadow will get even shorter. At solstice, the shadow's edge will be about 28,000 miles (45,000 kilometers) from the planet's surface, barely making it past the middle of the B ring. The moon Mimas is a few pixels wide, near the lower left in this image. This view looks toward the sunlit side of the rings from about 35 degrees above the ring plane. The image was taken in visible light with the Cassini spacecraft wide-angle camera on May 21, 2016. The view was obtained at a distance of approximately 2.0 million miles (3.2 million kilometers) from Saturn. Image scale is 120 miles (190 kilometers) per pixel. http://photojournal.jpl.nasa.gov/catalog/PIA20494

  18. Molecularly Engineered Energy Materials, an Energy Frontier Research Center

    SciTech Connect

    Ozolins, Vidvuds

    2016-09-28

    Molecularly Engineered Energy Materials (MEEM) was established as an interdisciplinary cutting-edge UCLA-based research center uniquely equipped to attack the challenge of rationally designing, synthesizing and testing revolutionary new energy materials. Our mission was to achieve transformational improvements in the performance of materials via controlling the nano-and mesoscale structure using selectively designed, earth-abundant, inexpensive molecular building blocks. MEEM has focused on materials that are inherently abundant, can be easily assembled from intelligently designed building blocks (molecules, nanoparticles), and have the potential to deliver transformative economic benefits in comparison with the current crystalline-and polycrystalline-based energy technologies. MEEM addressed basic science issues related to the fundamental mechanisms of carrier generation, energy conversion, as well as transport and storage of charge and mass in tunable, architectonically complex materials. Fundamental understanding of these processes will enable rational design, efficient synthesis and effective deployment of novel three-dimensional material architectures for energy applications. Three interrelated research directions were initially identified where these novel architectures hold great promise for high-reward research: solar energy generation, electrochemical energy storage, and materials for CO2 capture. Of these, the first two remained throughout the project performance period, while carbon capture was been phased out in consultation and with approval from BES program manager.

  19. Hemoglobin research and the origins of molecular medicine

    PubMed Central

    2008-01-01

    Much of our understanding of human physiology, and of many aspects of pathology, has its antecedents in laboratory and clinical studies of hemoglobin. Over the last century, knowledge of the genetics, functions, and diseases of the hemoglobin proteins has been refined to the molecular level by analyses of their crystallographic structures and by cloning and sequencing of their genes and surrounding DNA. In the last few decades, research has opened up new paradigms for hemoglobin related to processes such as its role in the transport of nitric oxide and the complex developmental control of the α-like and β-like globin gene clusters. It is noteworthy that this recent work has had implications for understanding and treating the prevalent diseases of hemoglobin, especially the use of hydroxyurea to elevate fetal hemoglobin in sickle cell disease. It is likely that current research will also have significant clinical implications, as well as lessons for other aspects of molecular medicine, the origin of which can be largely traced to this research tradition. PMID:18988877

  20. Chemical Technology Division, Annual technical report, 1991

    SciTech Connect

    Not Available

    1992-03-01

    Highlights of the Chemical Technology (CMT) Division`s activities during 1991 are presented. In this period, CMT conducted research and development in the following areas: (1) electrochemical technology, including advanced batteries and fuel cells; (2) technology for fluidized-bed combustion and coal-fired magnetohydrodynamics; (3) methods for treatment of hazardous and mixed hazardous/radioactive waste; (4) the reaction of nuclear waste glass and spent fuel under conditions expected for an unsaturated repository; (5) processes for separating and recovering transuranic elements from nuclear waste streams; (6) recovery processes for discharged fuel and the uranium blanket in the Integral Fast Reactor (IFR); (7) processes for removal of actinides in spent fuel from commercial water-cooled nuclear reactors and burnup in IFRs; and (8) physical chemistry of selected materials in environments simulating those of fission and fusion energy systems. The Division also conducts basic research in catalytic chemistry associated with molecular energy resources; chemistry of superconducting oxides and other materials of interest with technological application; interfacial processes of importance to corrosion science, catalysis, and high-temperature superconductivity; and the geochemical processes involved in water-rock interactions occurring in active hydrothermal systems. In addition, the Analytical Chemistry Laboratory in CMT provides a broad range of analytical chemistry support services to the technical programs at Argonne National Laboratory (ANL).

  1. Argonne National Laboratory High Energy Physics Division semiannual report of research activities, January 1, 1989--June 30, 1989

    SciTech Connect

    Not Available

    1989-01-01

    This paper discuss the following areas on High Energy Physics at Argonne National Laboratory: experimental program; theory program; experimental facilities research; accelerator research and development; and SSC detector research and development.

  2. Research Applications of Proteolytic Enzymes in Molecular Biology

    PubMed Central

    Mótyán, János András; Tóth, Ferenc; Tőzsér, József

    2013-01-01

    Proteolytic enzymes (also termed peptidases, proteases and proteinases) are capable of hydrolyzing peptide bonds in proteins. They can be found in all living organisms, from viruses to animals and humans. Proteolytic enzymes have great medical and pharmaceutical importance due to their key role in biological processes and in the life-cycle of many pathogens. Proteases are extensively applied enzymes in several sectors of industry and biotechnology, furthermore, numerous research applications require their use, including production of Klenow fragments, peptide synthesis, digestion of unwanted proteins during nucleic acid purification, cell culturing and tissue dissociation, preparation of recombinant antibody fragments for research, diagnostics and therapy, exploration of the structure-function relationships by structural studies, removal of affinity tags from fusion proteins in recombinant protein techniques, peptide sequencing and proteolytic digestion of proteins in proteomics. The aim of this paper is to review the molecular biological aspects of proteolytic enzymes and summarize their applications in the life sciences. PMID:24970197

  3. The latest progress in sugarcane molecular genetics research at the USDA-ARS, Sugarcane Research Laboratory

    USDA-ARS?s Scientific Manuscript database

    In 2005, two sugar molecular genetics tools were developed in the USDA-ARS, Southeast Area, Sugarcane Research Laboratory at Houma, LA. One is the high throughput fluorescence- and capillary electrophoregrams (CE)-based SSR genotyping tool and the other is single pollen collection and SSR genotyping...

  4. Insulated Masonry Cavity Walls. Proceedings of the Research Correlation Conference by the Building Research Institute, Division of Engineering and Industrial Research. (April 1960).

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC.

    Publication of conference paper texts include --(1) history and development of masonry cavity walls, (2) recent research related to determination of thermal and moisture resistance, (3) wall design and detailing, (4) design for crack prevention, (5) mortar specification characteristics, (6) performance experience with low-rise buildings, (7)…

  5. Psychological Sciences Division: 1985 Programs.

    ERIC Educational Resources Information Center

    Office of Naval Research, Washington, DC. Psychological Sciences Div.

    This booklet describes research carried out under sponsorship of the Psychological Sciences Division of the U.S. Office of Naval Research during Fiscal Year 1985. The booklet is divided into three programmatic research areas: (1) Engineering Psychology; (2) Personnel and Training; and (3) Group Psychology. Each program is described by an overview…

  6. Classical and Molecular Genetic Research on General Cognitive Ability.

    PubMed

    McGue, Matt; Gottesman, Irving I

    2015-01-01

    Arguably, no psychological variable has received more attention from behavioral geneticists than what has been called "general cognitive ability" (as well as "general intelligence" or "g"), and for good reason. GCA has a rich correlational network, implying that it may play an important role in multiple domains of functioning. GCA is highly correlated with various indicators of educational attainment, yet its predictive utility is not limited to academic achievement. It is also correlated with work performance, navigating the complexities of everyday life, the absence of various social pathologies (such as criminal convictions), and even health and mortality. Although the causal basis for these associations is not always known, it is nonetheless the case that research on GCA has the potential to provide insights into the origins of a wide range of important social outcomes. In this essay, our discussion of why GCA is considered a fundamentally important dimension of behavior on which humans differ is followed by a look at behavioral genetics research on CGA. We summarize behavioral genetics research that has sought to identify and quantify the total contributions of genetic and environmental factors to individual differences in GCA as well as molecular genetic research that has sought to identify genetic variants that underlie inherited effects. © 2015 The Hastings Center.

  7. UCSC genome browser: deep support for molecular biomedical research.

    PubMed

    Mangan, Mary E; Williams, Jennifer M; Lathe, Scott M; Karolchik, Donna; Lathe, Warren C

    2008-01-01

    The volume and complexity of genomic sequence data, and the additional experimental data required for annotation of the genomic context, pose a major challenge for display and access for biomedical researchers. Genome browsers organize this data and make it available in various ways to extract useful information to advance research projects. The UCSC Genome Browser is one of these resources. The official sequence data for a given species forms the framework to display many other types of data such as expression, variation, cross-species comparisons, and more. Visual representations of the data are available for exploration. Data can be queried with sequences. Complex database queries are also easily achieved with the Table Browser interface. Associated tools permit additional query types or access to additional data sources such as images of in situ localizations. Support for solving researcher's issues is provided with active discussion mailing lists and by providing updated training materials. The UCSC Genome Browser provides a source of deep support for a wide range of biomedical molecular research (http://genome.ucsc.edu).

  8. Major Programs | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention supports major scientific collaborations, research networks, investigator-initiated grants, postdoctoral training, and specialized resources across the United States. |

  9. Division Overview

    NASA Technical Reports Server (NTRS)

    Emerson, Dawn

    2016-01-01

    This presentation provides an overview of the research and engineering in the competency fields of advanced communications and intelligent systems with emphasis on advanced technologies, architecture definition and system development for application in current and future aeronautics and space systems.

  10. E-Division activities report

    SciTech Connect

    Barschall, H.H.

    1983-07-01

    This report describes some of the activities in E (Experimental Physics) Division during the past year. E-division carries out research and development in areas related to the missions of the Laboratory. Many of the activities are in pure and applied atomic and nuclear physics and in materials science. In addition, this report describes development work on accelerators and on instrumentation for plasma diagnostics, nitrogen exchange rates in tissue, and breakdown in gases by microwave pulses.

  11. E-Division activities report

    SciTech Connect

    Barschall, H.H.

    1981-07-01

    This report describes some of the activities in E (Experimental Physics) Division during the past year. E-Division carries out research and development in areas related to the missions of the Laboratory. Many of the activities are in pure and applied atomic and nuclear physics and in material science. In addition this report describes work on accelerators, microwaves, plasma diagnostics, determination of atmospheric oxygen and of nitrogen in tissue.

  12. Young Kim, PhD | Division of Cancer Prevention

    Cancer.gov

    Young S Kim, PhD, joined the Division of Cancer Prevention at the National Cancer Institute in 1998 as a Program Director who oversees and monitors NCI grants in the area of Nutrition and Cancer. She serves as an expert in nutrition, molecular biology, and genomics as they relate to cancer prevention. Dr. Kim assists with research initiatives that will advance nutritional science and lead to human health benefits. |

  13. Cognitive and Neural Sciences Division 1990 Programs.

    ERIC Educational Resources Information Center

    Vaughan, Willard S., Jr., Ed.

    Research and development efforts carried out under sponsorship of the Cognitive and Neural Sciences Division of the Office of Naval Research during fiscal year 1990 are described in this compilation of project description summaries. The Division's research is organized in three types of programs: (1) Cognitive Science (the human learner--cognitive…

  14. Chemical Technology Division annual technical report, 1993

    SciTech Connect

    Battles, J.E.; Myles, K.M.; Laidler, J.J.; Green, D.W.

    1994-04-01

    Chemical Technology (CMT) Division this period, conducted research and development in the following areas: advanced batteries and fuel cells; fluidized-bed combustion and coal-fired magnetohydrodynamics; treatment of hazardous waste and mixed hazardous/radioactive waste; reaction of nuclear waste glass and spent fuel under conditions expected for an unsaturated repository; separating and recovering transuranic elements, concentrating radioactive waste streams with advanced evaporators, and producing {sup 99}Mo from low-enriched uranium; recovering actinide from IFR core and blanket fuel in removing fission products from recycled fuel, and disposing removal of actinides in spent fuel from commercial water-cooled nuclear reactors; and physical chemistry of selected materials in environments simulating those of fission and fusion energy systems. The Division also conducts basic research in catalytic chemistry associated with molecular energy resources and novel ceramic precursors; materials chemistry of superconducting oxides, electrified metal/solution interfaces, molecular sieve structures, thin-film diamond surfaces, effluents from wood combustion, and molten silicates; and the geochemical processes involved in water-rock interactions. The Analytical Chemistry Laboratory in CMT also provides a broad range of analytical chemistry support.

  15. [Research advances in soil fungal diversity and molecular ecology].

    PubMed

    Zhang, Jing; Zhang, Huiwen; Li, Xinyu; Zhang, Chenggang

    2004-10-01

    Fungi are a kind of important soil microorganisms that participate in the decomposition of organic materials and supply nutrients to the plant through symbiosis. But, they can also reduce the output of food due to the existence of pathogenic fungi. Soil fungal diversity plays a fundamentally unique role in maintaining the balance of ecosystem and in supplying large amount of undeveloped resources for the people. In this paper, soil fungal diversity was expatiated from the viewpoints of species diversity, habitant diversity and functional diversity, and furthermore, the research advances in the molecular ecology of soil fungal diversity were reviewed from the aspects of the fungal diversity of farmland, woodland, pasture, extreme environment, and other complex environments. The affecting factors of soil fungal diversity were discussed, and the development trend of the study on soil fungal diversity was also approached.

  16. Mesoporous Silica Molecular Sieve based Nanocarriers: Transpiring Drug Dissolution Research.

    PubMed

    Pattnaik, Satyanarayan; Pathak, Kamla

    2017-01-01

    Improvement of oral bioavailability through enhancement of dissolution for poorly soluble drugs has been a very promising approach. Recently, mesoporous silica based molecular sieves have demonstrated excellent properties to enhance the dissolution velocity of poorly water-soluble drugs. Current research in this area is focused on investigating the factors influencing the drug release from these carriers, the kinetics of drug release and manufacturing approaches to scale-up production for commercial manufacture. This comprehensive review provides an overview of different methods adopted for synthesis of mesoporous materials, influence of processing factors on properties of these materials and drug loading methods. The drug release kinetics from mesoporous silica systems, the manufacturability and stability of these formulations are reviewed. Finally, the safety and biocompatibility issues related to these silica based materials are discussed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  17. Fluorescence Molecular Tomography: Principles and Potential for Pharmaceutical Research

    PubMed Central

    Stuker, Florian; Ripoll, Jorge; Rudin, Markus

    2011-01-01

    Fluorescence microscopic imaging is widely used in biomedical research to study molecular and cellular processes in cell culture or tissue samples. This is motivated by the high inherent sensitivity of fluorescence techniques, the spatial resolution that compares favorably with cellular dimensions, the stability of the fluorescent labels used and the sophisticated labeling strategies that have been developed for selectively labeling target molecules. More recently, two and three-dimensional optical imaging methods have also been applied to monitor biological processes in intact biological organisms such as animals or even humans. These whole body optical imaging approaches have to cope with the fact that biological tissue is a highly scattering and absorbing medium. As a consequence, light propagation in tissue is well described by a diffusion approximation and accurate reconstruction of spatial information is demanding. While in vivo optical imaging is a highly sensitive method, the signal is strongly surface weighted, i.e., the signal detected from the same light source will become weaker the deeper it is embedded in tissue, and strongly depends on the optical properties of the surrounding tissue. Derivation of quantitative information, therefore, requires tomographic techniques such as fluorescence molecular tomography (FMT), which maps the three-dimensional distribution of a fluorescent probe or protein concentration. The combination of FMT with a structural imaging method such as X-ray computed tomography (CT) or Magnetic Resonance Imaging (MRI) will allow mapping molecular information on a high definition anatomical reference and enable the use of prior information on tissue's optical properties to enhance both resolution and sensitivity. Today many of the fluorescent assays originally developed for studies in cellular systems have been successfully translated for experimental studies in animals. The opportunity of monitoring molecular processes non

  18. Scientific Scope | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention conducts and supports research to determine a person's risk of developing cancer and to find ways to reduce that risk. Through laboratory, clinical, and epidemiologic research, scientists have shown that the diseases of cancer occur not as single, catastrophic events, but rather as the result of a complex and long-evolving molecular process that can take decades. This long-term process of carcinogenesis provides time and opportunities to slow down, stop, or reverse the cellular changes that can become cancer. | DCP research spans the initiation of cancer and the occurrence of invasive disease in major organ sites. The overall goal is to detect changes and intervene early to prevent symptomatic disease and death.

  19. Structure and vulnerability of Pacific Northwest tidal wetlands – A summary of wetland climate change research by the Western Ecology Division, U.S. EPA

    USGS Publications Warehouse

    Folger, Christina L; Lee, Henry; Janousek, Christopher N.; Reusser, Deborah A.

    2014-01-01

    Climate change poses a serious threat to the tidal wetlands of the Pacific Northwest (PNW) region of the U.S. In response to this threat, scientists at the Western Ecology Division of the U.S. EPA at and the Western Fisheries Research Center of the U.S. Geological Survey, along with other partners, initiated a series of studies on the structure and vulnerability of tidal wetlands to climate change. One research thrust was to evaluate community structure of PNW marshes, experimentally assess the vulnerability of marsh plants to inundation and salinity stress (as would happen with sea level rise), and evaluate the utility of the National Wetland Inventory (NWI) classification system. Another research thrust was to develop tools that provide insights into possible impacts of climate change. This effort included enhancing the Sea Level Affecting Marshes Model (SLAMM) to predict the effects of sea level rise on submerged aquatic vegetation (Zostera marina) distributions, evaluating changes in river flow into coastal estuaries in response to precipitation changes, and synthesizing Pacific Coast estuary, watershed, and climate data in a downloadable tool. Because the research resulting from these efforts was published in multiple venues, we summarized them in this document. We anticipate that future research efforts by the U.S. EPA will continue with a focus on climate change impacts on a regional scale.

  20. E-Division activities report

    SciTech Connect

    Barschall, H.H.

    1984-07-01

    E (Experimental Physics) Division carries out basic and applied research in atomic and nuclear physics, in materials science, and in other areas related to the missions of the Laboratory. Some of the activities are cooperative efforts with other divisions of the Laboratory, and, in a few cases, with other laboratories. Many of the experiments are directly applicable to problems in weapons and energy, some have only potential applied uses, and others are in pure physics. This report presents abstracts of papers published by E (Experimental Physics) Division staff members between July 1983 and June 1984. In addition, it lists the members of the scientific staff of the division, including visitors and students, and some of the assignments of staff members on scientific committees. A brief summary of the budget is included.

  1. Molecular biology research to benefit patients with Entamoeba histolytica infection.

    PubMed

    Watanabe, Koji; Petri, William A

    2015-10-01

    The development of molecular microbiology has made it possible for us to deepen our understanding of the pathogenesis of amebiasis. Research using the trophozoite form of Entamoeba histolytica has clearly shown us the importance of the interface between the parasite and host cells in vitro. Immuno-pathogenesis after excystation was similarly well advanced by the use of a novel murine model of amebic colitis. However, it is still challenging to apply these findings to clinical and epidemiological settings. This is mainly because of the lack of a complete infection animal model of amebiasis by oral-fecal infection. Moreover, in vitro experiments have predominantly been performed using the same axenic cultured strain HM-1: IMSS isolated about 50 years ago, whereas highly diverse strains are prevalent all over the world. Translational research informed by clinical observations has the greatest potential for the development of effective interventions. Here, we highlight discoveries of the experiments designed from cohort observation and discuss remaining problems to be solved. © 2015 John Wiley & Sons Ltd.

  2. Expansion of Genetic Testing in the Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University from 2000 to 2013

    PubMed Central

    Adachi, Kaori

    2014-01-01

    Background At the Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University, we have been making an effort to establish a genetic testing facility that can provide the same screening procedures conducted worldwide. Methods Direct Sequencing of PCR products is the main method to detect point mutations, small deletions and insertions. Multiplex Ligation-dependent Probe Amplification (MLPA) was used to detect large deletions or insertions. Expansion of the repeat was analyzed for triplet repeat diseases. Original primers were constructed for 41 diseases when the reported primers failed to amplify the gene. Prediction of functional effects of human nsSNPs (PolyPhen) was used for evaluation of novel mutations. Results From January 2000 to September 2013, a total of 1,006 DNA samples were subjected to genetic testing in the Division of Functional Genomics, Research Center for Bioscience and Technology, Tottori University. The hospitals that requested genetic testing were located in 43 prefectures in Japan and in 11 foreign countries. The genetic testing covered 62 diseases, and mutations were detected in 287 out of 1,006 with an average mutation detection rate of 24.7%. There were 77 samples for prenatal diagnosis. The number of samples has rapidly increased since 2010. Conclusion In 2013, the next-generation sequencers were introduced in our facility and are expected to provide more comprehensive genetic testing in the near future. Nowadays, genetic testing is a popular and powerful tool for diagnosis of many genetic diseases. Our genetic testing should be further expanded in the future. PMID:25067876

  3. Home | Division of Cancer Prevention

    Cancer.gov

    Our Research The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into cancer. |

  4. 75 FR 70031 - Antitrust Division

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Antitrust Division Notice Pursuant to the National Cooperative Research and Production Act of 1993--Open... National Cooperative Research and Production Act of 1993, 15 U.S.C. 4301 et seq. (``the Act''), Open Axis... Consulting Corp., Miami Beach, FL; Mobiata, Ann Arbor, MI; AOl Marketing, Minneapolis, MN; eNett...

  5. Sustainable production of wood and non-wood forest products: Proceedings of IUFRO Division 5 Research Groups 5.11 and 5.12, Rotorua, New Zealand, March 11–15, 2003.

    Treesearch

    E.M. Donoghue; G.L. Benson; J.L. Chamberlain

    2004-01-01

    This proceedings is a collection of 18 papers and extended abstracts based on talks presented at the International Union of Forest Research Organizations (IUFRO) All Division 5 Conference, held in Rotorua, New Zealand, March 11–15, 2003. This conference emphasized the many ways that forest products research can contribute to sustainable choices in forest management....

  6. Review and Assessment of the Impact on Occupational Education Resulting from the Research and Development Activities Supported by the Division of Vocational and Technical Education of Illinois, Project RDC-A2-078.

    ERIC Educational Resources Information Center

    Carvell, Fred; Draheim, Kirk

    A 4-phase study was conducted to provide an objective third-party assessment of the effectiveness of research and development (R. & D.) projects supported by the Research and Development Unit (RDU) of the Illinois Division of Vocational and Technical Education. Activities during the four phases consisted of: (1) a preliminary review to obtain…

  7. Exploration: Past and Future Contributions of the Vertical Lift Community and the Flight Vehicle Research and Technology Division

    NASA Technical Reports Server (NTRS)

    Young, Larry A.; Aiken, Edwin W.

    2005-01-01

    Fulfillment of the exploration vision will require new cross-mission directorate and multi-technical discipline synergies in order to achieve the necessary long-term sustainability. In part, lessons from the Apollo-era, as well as more recent research efforts, suggest that the aeronautics and specifically the vertical lift research community can and will make significant contributions to the exploration effort. A number of notional concepts and associated technologies for such contributions are outlined.

  8. The Council On Undergraduate Research Division of Physics and Astronomy Distributed REU Program: Outcomes from the First Year of the Pilot Program

    NASA Astrophysics Data System (ADS)

    Armstrong, John C.; Jackson, Michael; Mateja, John

    2015-01-01

    Virtual collaborations are a feature of modern research groups. As such, the Council on Undergraduate Research Division of Physics and Astronomy developed a distributed REU pilot program. Projects in physics and astronomy spanned theoretical, experimental, and computational areas. Funding for the REU brought students from across the country to work with research groups at partner institutions. Students were selected from institutions with fewer opportunities for research, with a focus on students from smaller universities or community colleges. Faculty and students at the host institutions collaborated virtually during the summer, attending seminars and discussions via web conferencing. Interactions among the students in the six-campus REU cohort took place on-line with the experience culminating in an in-person meeting at Central Washington University that included presentations on the students' work. We present the outcome of the first year of this NSF-funded work, seeking to leverage the collective experience of faculty mentors across a spectrum of physics and astronomy projects. We will review some of the assessment data from the first year of the project, and present the benefits and challenges to such virtual collaborations.

  9. [Application of molecular pharmacognosy in research of Mongolian medicine].

    PubMed

    Li, Qianquan; Zhou, Lishe; Guo, Lanping; Li, Minhui; Zhang, Na; Yuan, Qingjun; Yuan, Yuan

    2011-10-01

    Molecular pharmacognosy has developed as a new borderline discipline. Using the method and technology of molecular pharmacognosy, a wide range of challenging problems were resolved, such as the identification of Mongolian medicinal raw materials, etiology of endangerment and protection of endangered Mongolian medicinal plants and animals, biosynthesis and bioregulation of active components in Mongolian medicinal plants, and characteristics and the molecular bases of Dao-di Herbs. So molecular pharmacognosy will provide the new methods and insights for modernization of Mongolian medicine.

  10. Impact of molecular genetic research on peanut cultivar development

    USDA-ARS?s Scientific Manuscript database

    Peanut (Arachis hypogaea L.) has lagged other crops on use of molecular genetic technology for cultivar development in part due to lack of investment, but also because of low levels of molecular polymorphism among cultivated varieties. Recent advances in molecular genetic technology have allowed res...

  11. Cognitive and Neural Sciences Division, 1991 Programs.

    ERIC Educational Resources Information Center

    Vaughan, Willard S., Ed.

    This report documents research and development performed under the sponsorship of the Cognitive and Neural Sciences Division of the Office of Naval Research in fiscal year 1991. It provides abstracts (title, principal investigator, project code, objective, approach, progress, and related reports) of projects of three program divisions (cognitive…

  12. New Study Designs | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention is expanding clinical research beyond standard trial designs to find interventions that may play a role in more than one prevalent disease. | The Division of Cancer Prevention is expanding clinical research beyond standard trial designs to find interventions that may play a role in more than one prevalent disease.

  13. Materials Sciences Division 1990 annual report

    SciTech Connect

    Not Available

    1990-12-31

    This report is the Materials Sciences Division`s annual report. It contains abstracts describing materials research at the National Center for Electron Microscopy, and for research groups in metallurgy, solid-state physics, materials chemistry, electrochemical energy storage, electronic materials, surface science and catalysis, ceramic science, high tc superconductivity, polymers, composites, and high performance metals.

  14. Description of the programs and facilities of the Physics Division

    SciTech Connect

    Not Available

    1992-10-01

    The major emphasis of our experimental nuclear physics research is in Heavy-Ion Physics, centered at the recently completed ATLAS facility. ATLAS is a designated National User Facility and is based on superconducting radio-frequency technology developed in the Physics Division. In addition, the Division has strong programs in Medium-Energy Physics and in Weak-Interaction Physics as well as in accelerator development. Our nuclear theory research spans a wide range of interests including nuclear dynamics with subnucleonic degrees of freedom, dynamics of many-nucleon systems, nuclear structure, and heavy-ion interactions. This research makes contact with experimental research programs in intermediate-energy and heavy-ion physics, both within the Division and on the national scale. The Atomic Physics program, the largest of which is accelerator-based, primarily uses ATLAS, a 5-MV Dynamitron accelerator and a highly stable 150-kV accelerator. A synchrotron-based atomic physics program has recently been initiated with current research with the National Synchrotron Light Source in preparation for a program at the Advanced Photon Source, at Argonne. The principal interests of the Atomic Physics program are in the interactions of fast atomic and molecular ions with solids and gases and in the laser spectroscopy of exotic species. The program is currently being expanded to take advantage of the unique research opportunities in synchrotron-based research that will present themselves when the Advanced Photon Source comes on line at Argonne. These topics are discussed briefly in this report.

  15. NCI Awards 18 Grants to Continue the Early Detection Research Network (EDRN) Biomarkers Effort | Division of Cancer Prevention

    Cancer.gov

    The NCI has awarded 18 grants to continue the Early Detection Research Network (EDRN), a national infrastructure that supports the integrated development, validation, and clinical application of biomarkers for the early detection of cancer. The awards fund 7 Biomarker Developmental Laboratories, 8 Clinical Validation Centers, 2 Biomarker Reference Laboratories, and a Data Management and Coordinating Center (DMCC). |

  16. Mining the Geophysical Research Abstracts Corpus: Mapping the impact of Free and Open Source Software on the EGU Divisions

    NASA Astrophysics Data System (ADS)

    Löwe, Peter; Klump, Jens; Robertson, Jesse

    2015-04-01

    Text mining is commonly employed as a tool in data science to investigate and chart emergent information from corpora of research abstracts, such as the Geophysical Research Abstracts (GRA) published by Copernicus. In this context current standards, such as persistent identifiers like DOI and ORCID, allow us to trace, cite and map links between journal publications, the underlying research data and scientific software. This network can be expressed as a directed graph which enables us to chart networks of cooperation and innovation, thematic foci and the locations of research communities in time and space. However, this approach of data science, focusing on the research process in a self-referential manner, rather than the topical work, is still in a developing stage. Scientific work presented at the EGU General Assembly is often the first step towards new approaches and innovative ideas to the geospatial community. It represents a rich, deep and heterogeneous source of geoscientific thought. This corpus is a significant data source for data science, which has not been analysed on this scale previously. In this work, the corpus of the Geophysical Research Abstracts is used for the first time as a data base for analyses of topical text mining. For this, we used a sturdy and customizable software framework, based on the work of Schmitt et al. [1]. For the analysis we used the High Performance Computing infrastructure of the German Research Centre for Geosciences GFZ in Potsdam, Germany. Here, we report on the first results from the analysis of the continuous spreading the of use of Free and Open Source Software Tools (FOSS) within the EGU communities, mapping the general increase of FOSS-themed GRA articles in the last decade and the developing spatial patterns of involved parties and FOSS topics. References: [1] Schmitt, L. M., Christianson, K.T, Gupta R..: Linguistic Computing with UNIX Tools, in Kao, A., Poteet S.R. (Eds.): Natural Language processing and Text

  17. Body Composition and Bone Mineral Density of Division 1 Collegiate Football Players, a Consortium of College Athlete Research (C-CAR) Study.

    PubMed

    Bosch, Tyler A; Carbuhn, Aaron; Stanforth, Philip R; Oliver, Jonathan M; Keller, Kathryn A; Dengel, Donald R

    2017-03-08

    The purpose of the present study was to generate normative data for total and regional body composition in Division 1 collegiate football players using dual-energy X-ray absorptiometry (DXA) and examine positional differences in total and regional measurements. Data was used from the Consortium of College Athlete Research (C-CAR) group. Four hundred-sixty-seven players were included in this study. Height, weight, total and regional fat mass, lean mass and bone mineral density were measured in each athlete in the preseason (June-August). Players were categorized by their offensive or defensive position for comparisons. Linemen tended to have the higher fat and lean mass measures (p<0.05 for all) compared to other positions. Positions that mirror each other (ex. Linemen) had similar body composition and body ratios. All positions were classified as overweight or obese based on BMI (>25 kg/m), yet other than offensive and defensive linemen, all positions had healthy percent body fat (13-20%) and low visceral fat mass (<500 g). The data presented here provide normative positional data for total and regional fat mass, lean mass, and bone density in Division 1 collegiate football players. Player position had a significant effect on body composition measures and is likely associated with on-field positional requirements. From a player health perspective, even though all positions had relatively high BMI values, the majority of positions had relatively low body fat and visceral fat, which is important for the health of players during and after their playing career. The increased accuracy and reliability of DXA provides greater information regarding positional differences in college football players compared to other methods.

  18. Biological and Environmental Research: Climate and Environmental Sciences Division: U.S./European Workshop on Climate Change Challenges and Observations

    SciTech Connect

    Mather, James; McCord, Raymond; Sisterson, Doug; Voyles, Jimmy

    2012-11-08

    The workshop aimed to identify outstanding climate change science questions and the observational strategies for addressing them. The scientific focus was clouds, aerosols, and precipitation, and the required ground- and aerial-based observations. The workshop findings will be useful input for setting priorities within the Department of Energy (DOE) and the participating European centers. This joint workshop was envisioned as the first step in enhancing the collaboration among these climate research activities needed to better serve the science community.

  19. Chemistry-Nuclear Chemistry Division. Progress report, October 1980-September 1981

    SciTech Connect

    Ryan, R.R.

    1982-05-01

    This report describes major progress in the research and development programs pursued by the Chemistry-Nuclear Chemistry Division of the Los Alamos National Laboratory during FY 1981. Topics covered include advanced analytical methods, atmospheric chemistry and transport, biochemistry, biomedical research, medical radioisotopes research, element migration and fixation, nuclear waste isolation research, inorganic and structural chemistry, isotope separation, analysis and applications, the newly established Nuclear Magnetic Resonance Center, atomic and molecular collisions, molecular spectroscopy, nuclear cosmochemistry, nuclear structure and reactions, pion charge exchange, radiochemical separations, theoretical chemistry, and unclassified weapons research.

  20. Biology Division progress report, October 1, 1991--September 30, 1993

    SciTech Connect

    Hartman, F.C.; Cook, J.S.

    1993-10-01

    This Progress Report summarizes the research endeavors of the Biology Division of the Oak Ridge National Laboratory during the period October 1, 1991, through September 30, 1993. The report is structured to provide descriptions of current activities and accomplishments in each of the Division`s major organizational units. Lists of information to convey the entire scope of the Division`s activities are compiled at the end of the report.

  1. Graduate Research Assistant Program for Professional Development at Oak Ridge National Laboratory (ORNL) Global Nuclear Security Technology Division (GNSTD)

    SciTech Connect

    Eipeldauer, Mary D; Shelander Jr, Bruce R

    2012-01-01

    The southeast is a highly suitable environment for establishing a series of nuclear safety, security and safeguards 'professional development' courses. Oak Ridge National Laboratory (ORNL) provides expertise in the research component of these subjects while the Y-12 Nuclear Security Complex handles safeguards/security and safety applications. Several universities (i.e., University of Tennessee, Knoxville (UTK), North Carolina State University, University of Michigan, and Georgia Technology Institute) in the region, which offer nuclear engineering and public policy administration programs, and the Howard Baker Center for Public Policy make this an ideal environment for learning. More recently, the Institute for Nuclear Security (INS) was established between ORNL, Y-12, UTK and Oak Ridge Associate Universities (ORAU), with a focus on five principal areas. These areas include policy, law, and diplomacy; education and training; science and technology; operational and intelligence capability building; and real-world missions and applications. This is a new approach that includes professional development within the graduate research assistant program addressing global needs in nuclear security, safety and safeguards.

  2. About DCP | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) is the primary unit of the National Cancer Institute devoted to cancer prevention research. DCP provides funding and administrative support to clinical and laboratory researchers, community and multidisciplinary teams, and collaborative scientific networks. |

  3. Physics division annual report 2000.

    SciTech Connect

    Thayer, K., ed.

    2001-10-04

    This report summarizes the research performed in 2000 in the Physics Division of Argonne National Laboratory. The Division's programs include operation of ATLAS as a national user facility, nuclear structure and reaction research, nuclear theory and medium energy physics research, and accelerator research and development. As the Nuclear Science Advisory Committee and the nuclear science community create a new long range plan for the field in 2001, it is clear that the research of the Division is closely aligned with and continues to help define the national goals of our field. The NSAC 2001 Long Range Plan recommends as the highest priority for major new construction the Rare Isotope Accelerator (RIA), a bold step forward for nuclear structure and nuclear astrophysics. The accelerator R&D in the Physics Division has made major contributions to almost all aspects of the RIA design concept and the community was convinced that this project is ready to move forward. 2000 saw the end of the first Gammasphere epoch at ATLAS, One hundred Gammasphere experiments were completed between January 1998 and March 2000, 60% of which used the Fragment Mass Analyzer to provide mass identification in the reaction. The experimental program at ATLAS then shifted to other important research avenues including proton radioactivity, mass measurements with the Canadian Penning Trap and measurements of high energy gamma-rays in nuclear reactions with the MSU/ORNL/Texas A&M BaF{sub 2} array. ATLAS provided 5460 beam-research hours for user experiments and maintained an operational reliability of 95%. Radioactive beams accounted for 7% of the beam time. ATLAS also provided a crucial test of a key RIA concept, the ability to accelerate multiple charge states in a superconducting heavy-ion linac. This new capability was immediately used to increase the performance for a scheduled experiment. The medium energy program continued to make strides in examining how the quark-gluon structure of matter

  4. Teaching Molecular Biological Techniques in a Research Content

    ERIC Educational Resources Information Center

    Stiller, John W.; Coggins, T. Chad

    2006-01-01

    Molecular biological methods, such as the polymerase chain reaction (PCR) and gel electrophoresis, are now commonly taught to students in introductory biology courses at the college and even high school levels. This often includes hands-on experience with one or more molecular techniques as part of a general biology laboratory. To assure that most…

  5. Teaching Molecular Biological Techniques in a Research Content

    ERIC Educational Resources Information Center

    Stiller, John W.; Coggins, T. Chad

    2006-01-01

    Molecular biological methods, such as the polymerase chain reaction (PCR) and gel electrophoresis, are now commonly taught to students in introductory biology courses at the college and even high school levels. This often includes hands-on experience with one or more molecular techniques as part of a general biology laboratory. To assure that most…

  6. Chemical Technology Division, Annual technical report, 1991

    SciTech Connect

    Not Available

    1992-03-01

    Highlights of the Chemical Technology (CMT) Division's activities during 1991 are presented. In this period, CMT conducted research and development in the following areas: (1) electrochemical technology, including advanced batteries and fuel cells; (2) technology for fluidized-bed combustion and coal-fired magnetohydrodynamics; (3) methods for treatment of hazardous and mixed hazardous/radioactive waste; (4) the reaction of nuclear waste glass and spent fuel under conditions expected for an unsaturated repository; (5) processes for separating and recovering transuranic elements from nuclear waste streams; (6) recovery processes for discharged fuel and the uranium blanket in the Integral Fast Reactor (IFR); (7) processes for removal of actinides in spent fuel from commercial water-cooled nuclear reactors and burnup in IFRs; and (8) physical chemistry of selected materials in environments simulating those of fission and fusion energy systems. The Division also conducts basic research in catalytic chemistry associated with molecular energy resources; chemistry of superconducting oxides and other materials of interest with technological application; interfacial processes of importance to corrosion science, catalysis, and high-temperature superconductivity; and the geochemical processes involved in water-rock interactions occurring in active hydrothermal systems. In addition, the Analytical Chemistry Laboratory in CMT provides a broad range of analytical chemistry support services to the technical programs at Argonne National Laboratory (ANL).

  7. Detailing the Division

    NASA Image and Video Library

    2010-10-11

    NASA Cassini spacecraft looks between Saturn A and B rings to spy structure in the Cassini Division. The Cassini Division, occupying the middle and left of the image, contains five dim bands of ring material, but not all of the division is shown here.

  8. Formative cell divisions: principal determinants of plant morphogenesis.

    PubMed

    Smolarkiewicz, Michalina; Dhonukshe, Pankaj

    2013-03-01

    Formative cell divisions utilizing precise rotations of cell division planes generate and spatially place asymmetric daughters to produce different cell layers. Therefore, by shaping tissues and organs, formative cell divisions dictate multicellular morphogenesis. In animal formative cell divisions, the orientation of the mitotic spindle and cell division planes relies on intrinsic and extrinsic cortical polarity cues. Plants lack known key players from animals, and cell division planes are determined prior to the mitotic spindle stage. Therefore, it appears that plants have evolved specialized mechanisms to execute formative cell divisions. Despite their profound influence on plant architecture, molecular players and cellular mechanisms regulating formative divisions in plants are not well understood. This is because formative cell divisions in plants have been difficult to track owing to their submerged positions and imprecise timings of occurrence. However, by identifying a spatiotemporally inducible cell division plane switch system applicable for advanced microscopy techniques, recent studies have begun to uncover molecular modules and mechanisms for formative cell divisions. The identified molecular modules comprise developmentally triggered transcriptional cascades feeding onto microtubule regulators that now allow dissection of the hierarchy of the events at better spatiotemporal resolutions. Here, we survey the current advances in understanding of formative cell divisions in plants in the context of embryogenesis, stem cell functionality and post-embryonic organ formation.

  9. Research by ESS Division for the Nevada Nuclear Waste Storage Investigations: Progress report, January-June 1985

    SciTech Connect

    Vaniman, D.

    1987-10-01

    Petrographic research for the Nevada Nuclear Waste Storage Investigations focused on xenolithic variability in the Topopah Spring Member and on variations of clinoptilolite composition at Yucca Mountain. Zeolite and smectite occurrences were considered in terms of their relation to a disturbed zone beneath the potential repository, and mineral stability experiments have produced a new clinoptilolite structure as a result of prolonged heating at low temperature. Limitations were defined on the abundance of erionite and of sulfur. X-ray diffraction studies lead to improved analytical methods. Progress was made in the comparative study of mineralogy in sand ramps and in faults. Geological modeling considered the differences of the diffusion of nonsorbing tracers in vertically and in horizontally fractured rock. Modeling also treated the diffusion of a nonsorbing tracer in devitrified and in zeolitized rock. The results of these experiments in all cases show relatively symmetrical two-dimensional diffusion patterns. Preliminary calculations compare the dispersion/diffusion of nonsorbing Tc with the dispersion/diffusion/sorption of U. 27 refs., 20 figs., 5 tabs.

  10. Overview of the Applied Aerodynamics Division

    NASA Technical Reports Server (NTRS)

    1991-01-01

    A major reorganization of the Aeronautics Directorate of the Langley Research Center occurred in early 1989. As a result of this reorganization, the scope of research in the Applied Aeronautics Division is now quite different than that in the past. An overview of the current organization, mission, and facilities of this division is presented. A summary of current research programs and sample highlights of recent research are also presented. This is intended to provide a general view of the scope and capabilities of the division.

  11. Environmental Transport Division: 1979 report

    SciTech Connect

    Murphy, C.E. Jr.; Schubert, J.F.; Bowman, W.W.; Adams, S.E.

    1980-03-01

    During 1979, the Environmental Transport Division (ETD) of the Savannah River Laboratory conducted atmospheric, terrestrial, aquatic, and marine studies, which are described in a series of articles. Separate abstracts were prepared for each. Publications written about the 1979 research are listed at the end of the report.

  12. newsletter | Division of Cancer Prevention

    Cancer.gov

    The Division of Cancer Prevention (DCP) conducts and supports research to determine a person's risk of cancer and to find ways to reduce the risk. This knowledge is critical to making progress against cancer because risk varies over the lifespan as genetic and epigenetic changes can transform healthy tissue into invasive cancer.

  13. Climate for Women in Industry: the Xerox Approach - An Example from the Division of Xerox Research and Technology

    NASA Astrophysics Data System (ADS)

    Chang, Shu

    2000-03-01

    Xerox has a very favorable reputation as an employer for women. In 1998, Xerox was cited three times as a top company for working women. "Working Mother" magazine, for the 13th consecutive year, chose Xerox as one of the 100 best companies for working mothers. "Working Women" magazine included Xerox as one of the top 25 public companies in the United States for executive women. "Latina Style" named Xerox as one of the 50 companies that offer the best professional opportunities for Hispanic women. However, Xerox is striving to be the employer of choice for women. Xerox views diversity as a business necessity and is beyond numbers and targets. To Xerox, diversity brings ideas, perspectives, and creativity that lead to more innovative solutions. To become the employer of choice for women, the approach from the Xerox Research and Technology organization (XR&T) is to improve the recruitment, retention, and advancement of women. The measurement of the improvement is an increasing representation of women at all levels. Championed by Dr. Mark B. Myers, Senior Vice President and head of XR&T, a dual effort has been implemented. At the request of Dr. Myers, an XR&T Women’s Council was formed in 1991. The mission of the Council has been to identify and promote opportunities for improving the work environment to support diversity and to advise XR&T management how to achieve this goal. Along with the Council, the mission of the XR&T management has been to follow through with Dr. Myers’ directions, Xerox policies, and the Council’s recommendations. By persistency, this dual effort is now paying off. Since 1991, the number of women among new hires and promotions has been steadily increasing. As for retention, XR&T is continuously creating, improving, and communicating policies and practices on career development programs, BWF tracking, diversity training, etc. Due to these proactive actions, a more supportive climate for women is emerging in XR&T. In our talk, we will

  14. Progress in nucleic acid research and molecular biology

    SciTech Connect

    Cohn, W.E. ); Moldave, K. )

    1989-01-01

    This book is organized under the following headings: Transposable elements in Drosophilia; Regulation of gene expression; Structure and function of repetitive and unusual sequences; Retroviruses; Molecular analysis of chromosomal translocation and gene insertion.

  15. Studies of acute and chronic radiation injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992: The JANUS Program Survival and Pathology Data

    SciTech Connect

    Grahn, D.; Wright, B.J.; Carnes, B.A.; Williamson, F.S.; Fox, C.

    1995-02-01

    A research reactor for exclusive use in experimental radiobiology was designed and built at Argonne National Laboratory in the 1960`s. It was located in a special addition to Building 202, which housed the Division of Biological and Medical Research. Its location assured easy access for all users to the animal facilities, and it was also near the existing gamma-irradiation facilities. The water-cooled, heterogeneous 200-kW(th) reactor, named JANUS, became the focal point for a range of radiobiological studies gathered under the rubic of {open_quotes}the JANUS program{close_quotes}. The program ran from about 1969 to 1992 and included research at all levels of biological organization, from subcellular to organism. More than a dozen moderate- to large-scale studies with the B6CF{sub 1} mouse were carried out; these focused on the late effects of whole-body exposure to gamma rays or fission neutrons, in matching exposure regimes. In broad terms, these studies collected data on survival and on the pathology observed at death. A deliberate effort was made to establish the cause of death. This archieve describes these late-effects studies and their general findings. The database includes exposure parameters, time of death, and the gross pathology and histopathology in codified form. A series of appendices describes all pathology procedures and codes, treatment or irradiation codes, and the manner in which the data can be accessed in the ORACLE database management system. A series of tables also presents summaries of the individual experiments in terms of radiation quality, sample sizes at entry, mean survival times by sex, and number of gross pathology and histopathology records.

  16. Teaching Cell Division: Basics and Recommendations.

    ERIC Educational Resources Information Center

    Smith, Mike U.; Kindfield, Ann C. H.

    1999-01-01

    Presents a concise overview of cell division that includes only the essential concepts necessary for understanding genetics and evolution. Makes recommendations based on published research and teaching experiences that can be used to judge the merits of potential activities and materials for teaching cell division. Makes suggestions regarding the…

  17. Teaching Cell Division: Basics and Recommendations.

    ERIC Educational Resources Information Center

    Smith, Mike U.; Kindfield, Ann C. H.

    1999-01-01

    Presents a concise overview of cell division that includes only the essential concepts necessary for understanding genetics and evolution. Makes recommendations based on published research and teaching experiences that can be used to judge the merits of potential activities and materials for teaching cell division. Makes suggestions regarding the…

  18. Building an Academic Colorectal Division

    PubMed Central

    Koltun, Walter A.

    2014-01-01

    Colon and rectal surgery is fully justified as a valid subspecialty within academic university health centers, but such formal recognition at the organizational level is not the norm. Creating a colon and rectal division within a greater department of surgery requires an unfailing commitment to academic concepts while promulgating the improvements that come in patient care, research, and teaching from a specialty service perspective. The creation of divisional identity then opens the door for a strategic process that will grow the division even more as well as provide benefits to the institution within which it resides. The fundamentals of core values, academic commitment, and shared success reinforced by receptive leadership are critical. Attention to culture, commitment, collaboration, control, cost, and compensation leads to a successful academic division of colon and rectal surgery. PMID:25067922

  19. Development Problems With Component Construction. Proceedings of Conference of the Building Research Institute, Division of Engineering and Industrial Research (Fall 1959).

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC.

    Publication of conference papers includes--(1) an overview of the ceiling system complex by a lighting manufacturer, (2) review of problems influencing the development of roofing systems, (3) description of cooperative research within the cement industry, and (4) description of joint research development of structural ceramic panels. Included…

  20. IFLA General Conference, 1984. General Research Libraries Division. Section on Parliamentary Libraries; Section on Public Libraries; Section on University and Other General Research Libraries. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on government libraries, public libraries, and research libraries presented at the 1984 IFLA general conference include: (1) "Library Services for Research" (Maria S. Pla de Menendez, Colombia); (2) "Interlibrary Loans, Present and Future: A Consideration for Academic Library Management" (Geoffrey G. Allen, Australia);…

  1. IFLA General Conference, 1984. General Research Libraries Division. Section on Parliamentary Libraries; Section on Public Libraries; Section on University and Other General Research Libraries. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on government libraries, public libraries, and research libraries presented at the 1984 IFLA general conference include: (1) "Library Services for Research" (Maria S. Pla de Menendez, Colombia); (2) "Interlibrary Loans, Present and Future: A Consideration for Academic Library Management" (Geoffrey G. Allen, Australia);…

  2. Development Problems With Component Construction. Proceedings of Conference of the Building Research Institute, Division of Engineering and Industrial Research (Fall 1959).

    ERIC Educational Resources Information Center

    National Academy of Sciences - National Research Council, Washington, DC.

    Publication of conference papers includes--(1) an overview of the ceiling system complex by a lighting manufacturer, (2) review of problems influencing the development of roofing systems, (3) description of cooperative research within the cement industry, and (4) description of joint research development of structural ceramic panels. Included…

  3. International Federation of Library Associations Annual Conference Papers. Education and Research Division: Library Theory and Research Section (47th, Leipzig, East Germany, August 17-22, 1981).

    ERIC Educational Resources Information Center

    Kolodziejska, Jadwiga; And Others

    Seven of these ten papers are concerned with library research in specific countries; the remaining three deal with library planning and ethics in research. Titles are "The Library as a Cultural Institution," by Jadwiga Kolodziejska, Poland; "The International Seminar 'Book and Library in Society' of the Polish Book and Readers…

  4. Accelerator Technology Division

    NASA Astrophysics Data System (ADS)

    1992-04-01

    In fiscal year (FY) 1991, the Accelerator Technology (AT) division continued fulfilling its mission to pursue accelerator science and technology and to develop new accelerator concepts for application to research, defense, energy, industry, and other areas of national interest. This report discusses the following programs: The Ground Test Accelerator Program; APLE Free-Electron Laser Program; Accelerator Transmutation of Waste; JAERI, OMEGA Project, and Intense Neutron Source for Materials Testing; Advanced Free-Electron Laser Initiative; Superconducting Super Collider; The High-Power Microwave Program; (Phi) Factory Collaboration; Neutral Particle Beam Power System Highlights; Accelerator Physics and Special Projects; Magnetic Optics and Beam Diagnostics; Accelerator Design and Engineering; Radio-Frequency Technology; Free-Electron Laser Technology; Accelerator Controls and Automation; Very High-Power Microwave Sources and Effects; and GTA Installation, Commissioning, and Operations.

  5. Molecular design concept for x-ray laser research

    SciTech Connect

    Rhodes, C.K.; Luk, Ting Shan; McPherson, A.; Boyer, K.

    1991-09-17

    The goal of this program is the construction of an x-ray laser in the kilovolt regime. Recent experimental results indicate that a new technique for the generation of strong amplification of x-ray wavelengths is feasible. It involves the combination of (1) a new ultrahigh brightness subpicosecond laser technology and (2) a recently discovered unique mode of strong-field interaction, particularly applicable to molecules. A concept of molecular x-ray laser design emerges from these considerations which matches the mode of excitation to the structure of the molecular system. The molecular approach enables the combination of very highly electronically excited conditions with an environment characteristic of dense cold matter, a general situation exceptionally conducive to x-ray amplification. Both high efficiency and wavelength tunability are intrinsic features of this method. 19 refs., 4 figs.

  6. Division Chief Meeting, April, 1929

    NASA Technical Reports Server (NTRS)

    1929-01-01

    Caption: 'LMAL division chiefs confer with the engineer-in-charge in April 1929. Left to right: E.A. Myers, Personnel Division; Edward R. Sharp, Property and Clerical Division; Thomas Carroll, Flight Test Division; Henry J.E. Reid, engineer in chief; Carlton Kemper, Power Plants Division; Elton Miller, aerodynamics division.'

  7. Training Program in the Molecular Basis of Breast Cancer Research

    DTIC Science & Technology

    1999-10-01

    superfamily" Spring Semester: 1999 Hugo J. Bellen "Genetic dissection of neurotransmitter release and endocytosis" Riccardo Dalla-Favera "Molecular...breast. Lee, Wen-Hwa, Ph.D. James Wang Linda deGraffenried Jennifer Gooch David Levin Ernesto Salcedo Jerry Alan Bates Jill Gilroy Jonathan

  8. Physics Division activities report, 1986--1987

    SciTech Connect

    Not Available

    1987-01-01

    This report summarizes the research activities of the Physics Division for the years 1986 and 1987. Areas of research discussed in this paper are: research on e/sup +/e/sup /minus// interactions; research on p/bar p/ interactions; experiment at TRIUMF; double beta decay; high energy astrophysics; interdisciplinary research; and advanced technology development and the SSC.

  9. A New Paradigm for Mentored Undergraduate Research in Molecular Microbiology

    ERIC Educational Resources Information Center

    Carson, Susan

    2007-01-01

    Science educators agree that an undergraduate research experience is critical for students who are considering graduate school or research careers. The process of researching a topic in the primary literature, designing experiments, implementing those experiments, and analyzing the results is essential in developing the analytical skills necessary…

  10. A New Paradigm for Mentored Undergraduate Research in Molecular Microbiology

    ERIC Educational Resources Information Center

    Carson, Susan

    2007-01-01

    Science educators agree that an undergraduate research experience is critical for students who are considering graduate school or research careers. The process of researching a topic in the primary literature, designing experiments, implementing those experiments, and analyzing the results is essential in developing the analytical skills necessary…

  11. Molecular communication among biological nanomachines: a layered architecture and research issues.

    PubMed

    Nakano, Tadashi; Suda, Tatsuya; Okaie, Yutaka; Moore, Michael J; Vasilakos, Athanasios V

    2014-09-01

    Molecular communication is an emerging communication paradigm for biological nanomachines. It allows biological nanomachines to communicate through exchanging molecules in an aqueous environment and to perform collaborative tasks through integrating functionalities of individual biological nanomachines. This paper develops the layered architecture of molecular communication and describes research issues that molecular communication faces at each layer of the architecture. Specifically, this paper applies a layered architecture approach, traditionally used in communication networks, to molecular communication, decomposes complex molecular communication functionality into a set of manageable layers, identifies basic functionalities of each layer, and develops a descriptive model consisting of key components of the layer for each layer. This paper also discusses open research issues that need to be addressed at each layer. In addition, this paper provides an example design of targeted drug delivery, a nanomedical application, to illustrate how the layered architecture helps design an application of molecular communication. The primary contribution of this paper is to provide an in-depth architectural view of molecular communication. Establishing a layered architecture of molecular communication helps organize various research issues and design concerns into layers that are relatively independent of each other, and thus accelerates research in each layer and facilitates the design and development of applications of molecular communication.

  12. IFLA General Conference, 1987. Division of Education and Research. Theory and Research Section. Round Table on Library History. Round Table of Editors of Library Journals. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    Four of the 10 papers in this collection are presented in the original language, i.e., either French or German, and English translations are provided for two of them. The papers are: (1) "UAP (Universal Availability of Publications) and Its Relation to Research and Education" (Maurice B. Line); (2) "Zehn Jahre IFLA-Abteilung…

  13. IFLA General Conference, 1990. Division of Education and Research: Section of Education and Training; Section of Library Theory and Research; Library History, Round Table; Research in Reading, Round Table; Editors of Library Journals, Round Table; and Continuing Professional Education, Round Table; Joint Workshop Papers. Booklet 7.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    The 21 papers in this collection were presented at the meetings of two sections and three round tables of the Division of Education and Research: (1) "Library and Information Services in Culturally Diverse Communities" (Cheryl Metoyer-Duran); (2) "Library Education in a Pluralistic Society" (Shmuel Sever); (3) "Each One an Individual:…

  14. IFLA General Conference, 1990. Division of Education and Research: Section of Education and Training; Section of Library Theory and Research; Library History, Round Table; Research in Reading, Round Table; Editors of Library Journals, Round Table; and Continuing Professional Education, Round Table; Joint Workshop Papers. Booklet 7.

    ERIC Educational Resources Information Center

    International Federation of Library Associations, The Hague (Netherlands).

    The 21 papers in this collection were presented at the meetings of two sections and three round tables of the Division of Education and Research: (1) "Library and Information Services in Culturally Diverse Communities" (Cheryl Metoyer-Duran); (2) "Library Education in a Pluralistic Society" (Shmuel Sever); (3) "Each One an Individual:…

  15. IFLA General Conference, 1992. Division of Education and Research: Editors of Library Journals (RT); Section on Research in Reading; Section on Women's Interest in Librarianship; Section on Education and Training; Continuing Professional Education (RT); Section on Library Theory and Research. Papers.

    ERIC Educational Resources Information Center

    International Federation of Library Associations and Institutions, London (England).

    The following 19 papers were delivered at the 1992 annual meeting of the International Federation of Library Associations and Institutions for the Division of Education and Research: (1) "Across the Frontiers: Impact of Foreign Journals in Library Science in India: A Citation Analysis" (M. A. Gopinath); (2) "Children and Reading in…

  16. Translational research in glioblastoma multiforme: molecular criteria for patient selection.

    PubMed

    Rosell, Rafael; de Las Peñas, Ramon; Balaña, Carme; Santarpia, Mariacarmela; Salazar, Fernanda; de Aguirre, Itziar; Reguart, Noemi; Villa, Salvador; Wei, Jia; Ramirez, Jose Luis; Molina, Miguel Angel; Ramon y Cajal, Santiago; Jablons, David; Taron, Miquel

    2008-04-01

    In spite of the dismal outcome of glioblastoma multiforme (GBM), we are in a position to provide a ray of hope to patients and families. Methylation of MGMT in tumor occurs in approximately a third of patients and predicts meaningful response and survival to adjuvant radiotherapy plus temozolomide. Limited access to tumor tissue in some patients could be circumvented by examining MGMT methylation in circulating serum DNA, although this approach needs to be validated. Molecular signatures are also promising prognostic and predictive markers, and clinical trials should be carried out to validate their use in the selection of patients for specific targeted therapies. Gene expression by quantitative PCR of key components of these molecular signatures could pave the way for easy identification of different subgroups of patients. Translational clinical trials are warranted in order to detect the subgroups of patients resistant to radiotherapy who may derive benefit from novel therapies, including antiangiogenic drugs.

  17. Grete Kellenberger-Gujer: Molecular biology research pioneer.

    PubMed

    Citi, Sandra; Berg, Douglas E

    2016-01-01

    Grete Kellenberger-Gujer was a Swiss molecular biologist who pioneered fundamental studies of bacteriophage in the mid-20(th) century at the University of Geneva. Her life and career stories are reviewed here, focusing on her fundamental contributions to our early understanding of phage biology via her insightful analyses of phenomena such as the lysogenic state of a temperate phage (λ), genetic recombination, radiation's in vivo consequences, and DNA restriction-modification; on her creative personality and interactions with peers; and how her academic advancement was affected by gender, societal conditions and cultural attitudes of the time. Her story is important scientifically, putting into perspective features of the scientific community from just before the molecular biology era started through its early years, and also sociologically, in illustrating the numerous "glass ceilings" that, especially then, often hampered the advancement of creative women.

  18. Grete Kellenberger-Gujer: Molecular biology research pioneer

    PubMed Central

    Citi, Sandra; Berg, Douglas E.

    2016-01-01

    ABSTRACT Grete Kellenberger-Gujer was a Swiss molecular biologist who pioneered fundamental studies of bacteriophage in the mid-20th century at the University of Geneva. Her life and career stories are reviewed here, focusing on her fundamental contributions to our early understanding of phage biology via her insightful analyses of phenomena such as the lysogenic state of a temperate phage (λ), genetic recombination, radiation's in vivo consequences, and DNA restriction-modification; on her creative personality and interactions with peers; and how her academic advancement was affected by gender, societal conditions and cultural attitudes of the time. Her story is important scientifically, putting into perspective features of the scientific community from just before the molecular biology era started through its early years, and also sociologically, in illustrating the numerous “glass ceilings” that, especially then, often hampered the advancement of creative women. PMID:27607140

  19. Hybrid Molecular and Spin-Semiconductor Based Research

    DTIC Science & Technology

    2005-02-02

    13. ABSTRACT (Maximum 200 words) This project has three thrusts. Thrust I is entitled “Integrated Bacteriorhodopsin -Based Photodetectors...studied Thrust I: Integrated Bacteriorhodopsin -Based Photodetectors The objective of this thrust was to enable a new class of optoelectronic devices by...nature of Bacteriorhodopsin (bR) have been utilized to construct novel molecular sensors, modulators, or imaging devices. The light induced photovoltage

  20. Training Program in the Molecular Basis of Breast Cancer Research.

    DTIC Science & Technology

    1997-10-01

    97-05/31/01 04/01/96-03/31/00 06/01/96-05/31/99 Structure- Function Relationships in the FAD- and FMN-Containing Enzymes, NADPH - Cytochrome P450 ...Prostaglandin 19- and 20- Hydorxylation by Cytochrome P450 GM31296 Structural & Modularity in Synthase GM52419 Functional Nitric Oxide 06/01...germ cells whereas DNA ligase lll-b functions in meiotic recombination. A manuscript describing these studies has been published in Molecular and

  1. Chemical Sciences Division: Annual report 1992

    SciTech Connect

    Not Available

    1993-10-01

    The Chemical Sciences Division (CSD) is one of twelve research Divisions of the Lawrence Berkeley Laboratory, a Department of Energy National Laboratory. The CSD is composed of individual groups and research programs that are organized into five scientific areas: Chemical Physics, Inorganic/Organometallic Chemistry, Actinide Chemistry, Atomic Physics, and Physical Chemistry. This report describes progress by the CSD for 1992. Also included are remarks by the Division Director, a description of work for others (United States Office of Naval Research), and appendices of the Division personnel and an index of investigators. Research reports are grouped as Fundamental Interactions (Photochemical and Radiation Sciences, Chemical Physics, Atomic Physics) or Processes and Techniques (Chemical Energy, Heavy-Element Chemistry, and Chemical Engineering Sciences).

  2. WESTERN ECOLOGY DIVISION - GENERAL INFORMATION SHEET

    EPA Science Inventory

    abstract for flyer - general information The Western Ecology Division (WED), part of EPAs National Health and Environmental Effects Research Laboratory, provides information to EPA offices and regions nationwide to improve understanding of how human activities affect estuarine,...

  3. Chemical Sciences Division annual report 1994

    SciTech Connect

    1995-06-01

    The division is one of ten LBL research divisions. It is composed of individual research groups organized into 5 scientific areas: chemical physics, inorganic/organometallic chemistry, actinide chemistry, atomic physics, and chemical engineering. Studies include structure and reactivity of critical reaction intermediates, transients and dynamics of elementary chemical reactions, and heterogeneous and homogeneous catalysis. Work for others included studies of superconducting properties of high-{Tc} oxides. In FY 1994, the division neared completion of two end-stations and a beamline for the Advanced Light Source, which will be used for combustion and other studies. This document presents summaries of the studies.

  4. Advanced synchrotron-based and globar-sourced molecular (micro) spectroscopy contributions to advances in food and feed research on molecular structure, mycotoxin determination, and molecular nutrition.

    PubMed

    Shi, Haitao; Yu, Peiqiang

    2017-04-17

    Mycotoxin contamination has been a worldwide problem for food and feeds production for a long time. There is an obviously increased focus of the food and feed industry toward the reduction of mycotoxin concentration in both the raw materials and finished products. Therefore, both effective qualitative and quantitative techniques for the determination of mycotoxins are required to minimize their harmful effects. Conventional wet chemical methods usually are time-consuming, expensive, and rely on complex extraction and cleanup pretreatments. Synchrotron-based and globar-based molecular spectroscopy have shown great potential to be developed as rapid and nondestructive tools for the determination of molecular structure, molecular nutrition and mycotoxins in feed and food. This article reviews the common types of mycotoxins in feed and food, their toxicity, as well as the conventional detection methods. The principle of advanced molecular spectroscopy techniques and their application prospects for mycotoxin detection are discussed. Recent progress in food and feed research with molecular spectroscopy techniques is highlighted. This review provides a potential and insight into how to determine the structure and mycotoxins of feed and food on a molecular basis with advanced Synchrotron-based and globar-based molecular (micro) spectroscopy.

  5. Friday's Agenda | Division of Cancer Prevention

    Cancer.gov

    TimeAgenda8:00 am - 8:10 amWelcome and Opening RemarksLeslie Ford, MDAssociate Director for Clinical ResearchDivision of Cancer Prevention, NCIEva Szabo, MD Chief, Lung and Upper Aerodigestive Cancer Research GroupDivision of Cancer Prevention, NCI8:10 am - 8:40 amClinical Trials Statistical Concepts for Non-StatisticiansKevin Dodd, PhD |

  6. Chemical Technology Division annual technical report, 1992

    SciTech Connect

    Battles, J.E.; Myles, K.M.; Laidler, J.J.; Green, D.W.

    1993-06-01

    In this period, CMT conducted research and development in the following areas: (1) electrochemical technology, including advanced batteries and fuel cells; (2) technology for fluidized-bed combustion and coal-fired magnetohydrodynamics; (3) methods for treatment of hazardous waste, mixed hazardous/radioactive waste, and municipal solid waste; (4) the reaction of nuclear waste glass and spent fuel under conditions expected for an unsaturated repository; (5) processes for separating and recovering transuranic elements from nuclear waste streams, treating water contaminated with volatile organics, and concentrating radioactive waste streams; (6) recovery processes for discharged fuel and the uranium blanket in the Integral Fast Reactor (EFR); (7) processes for removal of actinides in spent fuel from commercial water-cooled nuclear reactors and burnup in IFRs; and (8) physical chemistry of selected materials (corium; Fe-U-Zr, tritium in LiAlO{sub 2} in environments simulating those of fission and fusion energy systems. The Division also conducts basic research in catalytic chemistry associated with molecular energy resources and novel` ceramic precursors; materials chemistry of superconducting oxides, electrified metal/solution interfaces, and molecular sieve structures; and the geochemical processes involved in water-rock interactions occurring in active hydrothermal systems. In addition, the Analytical Chemistry Laboratory in CMT provides a broad range of analytical chemistry support services to the technical programs at Argonne National Laboratory (ANL).

  7. Applying the results of education research to help students learn more: peer instruction and clicker questions in upper-division courses

    NASA Astrophysics Data System (ADS)

    Pepper, Rachel E.; Chasteen, Stephanie V.; Pollock, Steven J.; Perkins, Katherine K.

    2014-11-01

    The physics faculty at the University of Colorado have transformed four upper-division courses: Classical Mechanics/Math Methods, Electricity and Magnetism (E&M) I and II, and Quantum Mechanics. We discuss these transformations as a model for other upper-division courses, such as fluid mechanics, focusing on one of the changes made in the transformation effort: the addition of peer instruction (``clicker questions'') to lecture. The goals of our course transformation were to improve student learning and to develop materials and approaches that other faculty could easily adopt or adapt. In this talk, we review the evidence for effectiveness of peer instruction, discuss our implementation, and present evidence of improved student learning in our transformed upper division courses. Tips for effective use of peer instruction and banks of clicker questions available for fluid mechanics will also be discussed. Our curriculum materials are free and available at http://per.colorado.edu/sei.

  8. High Pressure Materials Research: Novel Extended Phases of Molecular Triatomics

    SciTech Connect

    Yoo, C

    2004-05-26

    Application of high pressure significantly alters the interatomic distance and thus the nature of intermolecular interaction, chemical bonding, molecular configuration, crystal structure, and stability of solid [1]. With modern advances in high-pressure technologies [2], it is feasible to achieve a large (often up to a several-fold) compression of lattice, at which condition material can be easily forced into a new physical and chemical configuration [3]. The high-pressure thus offers enhanced opportunities to discover new phases, both stable and metastable ones, and to tune exotic properties in a wide-range of atomistic length scale, substantially greater than (often being several orders of) those achieved by other thermal (varying temperatures) and chemical (varying composition or making alloys) means. Simple molecular solids like H{sub 2}, C, CO{sub 2}, N{sub 2}, O{sub 2}, H{sub 2}O, CO, NH{sub 3}, and CH{sub 4} are bounded by strong covalent intramolecular bonds, yet relatively weak intermolecular bonds of van der Waals and/or hydrogen bonds. The weak intermolecular bonds make these solids highly compressible (i.e., low bulk moduli typically less than 10 GPa), while the strong covalent bonds make them chemically inert at least initially at low pressures. Carbon-carbon single bonds, carbon-oxygen double bonds and nitrogen-nitrogen triple bonds, for example, are among the strongest. These molecular forms are, thus, often considered to remain stable in an extended region of high pressures and high temperatures. High stabilities of these covalent molecules are also the basis of which their mixtures are often presumed to be the major detonation products of energetic materials as well as the major constituents of giant planets. However, their physical/chemical stabilities are not truly understood at those extreme pressure-temperature conditions. In fact, an increasing amount of experimental evidences contradict the assumed stability of these materials at high

  9. Progress in nucleic acid research and molecular biology

    SciTech Connect

    Cohn, W.E.; Moldave, K.

    1988-01-01

    Complementary Use of Chemical Modification and Site-Directed Mutagenesis to Probe Structure-Activity Relationships in Enzymes. Mechanisms of the Antiviral Action of Inteferons. Modulation of Cellular Genes by Oncogenes. DNA Damage Produced by Ionizing Radiation in Mammalian Cells: Identities, Mechanisms of Formation, and Reparability. Human Ferritin Gene Expression. Molecular Biology of the Insulin Receptor. Cap-Binding Proteins of Eukaryotic Messenger RNA: Functions in Initiation and Control of Translation. Physical Monitoring of Meiotic and Mitotic Recombination in Yeast. Early Signals Underlying the Induction of the c-fos and c-myc Genes in Quiescent Fibroblasts: Studies with Bombesin and Other Growth Factors. Each chapter includes references.

  10. Division: The Sleeping Dragon

    ERIC Educational Resources Information Center

    Watson, Anne

    2012-01-01

    Of the four mathematical operators, division seems to not sit easily for many learners. Division is often described as "the odd one out". Pupils develop coping strategies that enable them to "get away with it". So, problems, misunderstandings, and misconceptions go unresolved perhaps for a lifetime. Why is this? Is it a case of "out of sight out…

  11. Division: The Sleeping Dragon

    ERIC Educational Resources Information Center

    Watson, Anne

    2012-01-01

    Of the four mathematical operators, division seems to not sit easily for many learners. Division is often described as "the odd one out". Pupils develop coping strategies that enable them to "get away with it". So, problems, misunderstandings, and misconceptions go unresolved perhaps for a lifetime. Why is this? Is it a case of "out of sight out…

  12. Physics Division annual review, April 1, 1992--March 31, 1993

    SciTech Connect

    Thayer, K.J.

    1993-08-01

    This document is the annual review of the Argonne National Laboratory Physics Division for the period April 1, 1992--March 31, 1993. Work on the ATLAS device is covered, as well as work on a number of others in lab, as well as collaborative projects. Heavy ion nuclear physics research looked at quasi-elastic, and deep-inelastic reactions, cluster states, superdeformed nuclei, and nuclear shape effects. There were programs on accelerator mass spectroscopy, and accelerator and linac development. There were efforts in medium energy nuclear physics, weak interactions, theoretical nuclear and atomic physics, and experimental atomic and molecular physics based on accelerators and synchrotron radiation.

  13. Physics division. Progress report, January 1, 1995--December 31, 1996

    SciTech Connect

    Stewart, M.; Bacon, D.S.; Aine, C.J.; Bartsch, R.R.

    1997-10-01

    This issue of the Physics Division Progress Report describes progress and achievements in Physics Division research during the period January 1, 1995-December 31, 1996. The report covers the five main areas of experimental research and development in which Physics Division serves the needs of Los Alamos National Laboratory and the nation in applied and basic sciences: (1) biophysics, (2) hydrodynamic physics, (3) neutron science and technology, (4) plasma physics, and (5) subatomic physics. Included in this report are a message from the Division Director, the Physics Division mission statement, an organizational chart, descriptions of the research areas of the five groups in the Division, selected research highlights, project descriptions, the Division staffing and funding levels for FY95-FY97, and a list of publications and presentations.

  14. Health, Safety, and Environment Division

    SciTech Connect

    Wade, C

    1992-01-01

    The primary responsibility of the Health, Safety, and Environmental (HSE) Division at the Los Alamos National Laboratory is to provide comprehensive occupational health and safety programs, waste processing, and environmental protection. These activities are designed to protect the worker, the public, and the environment. Meeting these responsibilities requires expertise in many disciplines, including radiation protection, industrial hygiene, safety, occupational medicine, environmental science and engineering, analytical chemistry, epidemiology, and waste management. New and challenging health, safety, and environmental problems occasionally arise from the diverse research and development work of the Laboratory, and research programs in HSE Division often stem from these applied needs. These programs continue but are also extended, as needed, to study specific problems for the Department of Energy. The results of these programs help develop better practices in occupational health and safety, radiation protection, and environmental science.

  15. Molecular Genetic Tools and Techniques for Marchantia polymorpha Research.

    PubMed

    Ishizaki, Kimitsune; Nishihama, Ryuichi; Yamato, Katsuyuki T; Kohchi, Takayuki

    2016-02-01

    Liverworts occupy a basal position in the evolution of land plants, and are a key group to address a wide variety of questions in plant biology. Marchantia polymorpha is a common, easily cultivated, dioecious liverwort species, and is emerging as an experimental model organism. The haploid gametophytic generation dominates the diploid sporophytic generation in its life cycle. Genetically homogeneous lines in the gametophyte generation can be established easily and propagated through asexual reproduction, which aids genetic and biochemical experiments. Owing to its dioecy, male and female sexual organs are formed in separate individuals, which enables crossing in a fully controlled manner. Reproductive growth can be induced at the desired times under laboratory conditions, which helps genetic analysis. The developmental process from a single-celled spore to a multicellular body can be observed directly in detail. As a model organism, molecular techniques for M. polymorpha are well developed; for example, simple and efficient protocols of Agrobacterium-mediated transformation have been established. Based on them, various strategies for molecular genetics, such as introduction of reporter constructs, overexpression, gene silencing and targeted gene modification, are available. Herein, we describe the technologies and resources for reverse and forward genetics in M. polymorpha, which offer an excellent experimental platform to study the evolution and diversity of regulatory systems in land plants.

  16. Coordinated Research Projects of the IAEA Atomic and Molecular Data Unit

    SciTech Connect

    Braams, B. J.; Chung, H.-K.

    2011-05-11

    The IAEA Atomic and Molecular Data Unit is dedicated to the provision of databases for atomic, molecular and plasma-material interaction (AM/PMI) data that are relevant for nuclear fusion research. IAEA Coordinated Research Projects (CRPs) are the principal mechanism by which the Unit encourages data evaluation and the production of new data. Ongoing and planned CRPs on AM/PMI data are briefly described here.

  17. 25 years of African trypanosome research: From description to molecular dissection and new drug discovery.

    PubMed

    Matthews, Keith R

    2015-01-01

    The Molecular Parasitology conference was first held at the Marine Biological laboratory, Woods Hole, USA 25 years ago. Since that first meeting, the conference has evolved and expanded but has remained the showcase for the latest research developments in molecular parasitology. In this perspective, I reflect on the scientific discoveries focussed on African trypanosomes (Trypanosoma brucei spp.) that have occurred since the inaugural MPM meeting and discuss the current and future status of research on these parasites.

  18. The Future is Now. HBCU/ONR (Historically Black Colleges and Universities/Office of Naval Research) Planning Workshop, Mathematical Sciences Division Held in Washington, DC on October 28-29, 1985.

    DTIC Science & Technology

    1986-09-30

    Numerical Analysis and Related Computational Architecture o Mathematical and Compjtational Statistics and Special Programs o Operations Research o...For analysis purposes, a mean designation of ŗ" or less was considered less than satisfactory and the basis for reassessment and serious planning...new fiscal year, some of the Division’s priorities are: applied analysis , numerical analysis and related computational architecture, mathematical and

  19. Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

    PubMed Central

    Shinjo, K; Koland, J G; Hart, M J; Narasimhan, V; Johnson, D I; Evans, T; Cerione, R A

    1990-01-01

    We have isolated cDNA clones from a human placental library that code for a low molecular weight GTP-binding protein originally designated Gp (also called G25K). This identification is based on comparisons with the available peptide sequences for the purified human Gp protein and the use of two highly specific anti-peptide antibodies. The predicted amino acid sequence of the protein is very similar to those of various members of the ras superfamily of low molecular weight GTP-binding proteins, including the N-, Ki-, and Ha-ras proteins (30-35% identical), the rho proteins (approximately 50% identical), and the rac proteins (approximately 70% identical). The highest degree of sequence identity (80%) is found with the Saccharomyces cerevisiae cell-division-cycle protein CDC42. The human placental gene, which we designate CDC42Hs, complements the cdc42-1 mutation in S. cerevisiae, which suggests that this GTP-binding protein is the human homolog of the yeast protein. Images PMID:2124704

  20. Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

    PubMed

    Shinjo, K; Koland, J G; Hart, M J; Narasimhan, V; Johnson, D I; Evans, T; Cerione, R A

    1990-12-01

    We have isolated cDNA clones from a human placental library that code for a low molecular weight GTP-binding protein originally designated Gp (also called G25K). This identification is based on comparisons with the available peptide sequences for the purified human Gp protein and the use of two highly specific anti-peptide antibodies. The predicted amino acid sequence of the protein is very similar to those of various members of the ras superfamily of low molecular weight GTP-binding proteins, including the N-, Ki-, and Ha-ras proteins (30-35% identical), the rho proteins (approximately 50% identical), and the rac proteins (approximately 70% identical). The highest degree of sequence identity (80%) is found with the Saccharomyces cerevisiae cell-division-cycle protein CDC42. The human placental gene, which we designate CDC42Hs, complements the cdc42-1 mutation in S. cerevisiae, which suggests that this GTP-binding protein is the human homolog of the yeast protein.

  1. Molecular cloning of the gene for the human placental GTP-binding protein G sub p (G25K): Identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42

    SciTech Connect

    Shinjo, K.; Koland, J.G.; Hart, M.J.; Narasimhan, V.; Cerione, R.A. ); Johnson, D.I. ); Evans, T. )

    1990-12-01

    The authors have isolated cDNA clones from a human placental library that code for a low molecular weight GTP-binding protein originally designated G{sub p} (also called G25K). This identification is based on comparisons with the available peptide sequences for the purified human G{sub p} protein and the use of two highly specific anti-peptide antibodies. The predicted amino acid sequence of the protein is very similar to those of various members of the ras superfamily of low molecular weight GTP-binding proteins, including the N-, Ki-, and Ha-ras proteins (30-35% identical), the rho proteins and the rac proteins. The highest degree of sequence identity (80%) is found with the Saccharomyces cerevisiae cell division-cycle protein CDC42. The human placental gene, which they designate CDC42Hs, complements the cdc42-1 mutation in S. cerevisiae, which suggests that this GTP-binding protein is the human homolog of the yeast protein.

  2. Division Iv: Stars

    NASA Astrophysics Data System (ADS)

    Corbally, Christopher; D'Antona, Francesca; Spite, Monique; Asplund, Martin; Charbonnel, Corinne; Docobo, Jose Angel; Gray, Richard O.; Piskunov, Nikolai E.

    2012-04-01

    This Division IV was started on a trial basis at the General Assembly in The Hague 1994 and was formally accepted at the Kyoto General Assembly in 1997. Its broad coverage of ``Stars'' is reflected in its relatively large number of Commissions and so of members (1266 in late 2011). Its kindred Division V, ``Variable Stars'', has the same history of its beginning. The thinking at the time was to achieve some kind of balance between the number of members in each of the 12 Divisions. Amid the current discussion of reorganizing the number of Divisions into a more compact form it seems advisable to make this numerical balance less of an issue than the rationalization of the scientific coverage of each Division, so providing more effective interaction within a particular field of astronomy. After all, every star is variable to a certain degree and such variability is becoming an ever more powerful tool to understand the characteristics of every kind of normal and peculiar star. So we may expect, after hearing the reactions of members, that in the restructuring a single Division will result from the current Divisions IV and V.

  3. High Pressure Materials Research: Novel Extended Phases of Molecular Triatomics

    SciTech Connect

    Yoo, Choong-Shik

    2006-01-27

    Application of high pressure significantly alters the interatomic distance and thus the nature of intermolecular interaction, chemical bonding, molecular configuration, crystal structure, and stability of solid. With modern advances in high-pressure technologies, it is feasible to achieve a large (often up to a several-fold) compression of lattice, at which condition material can be easily forced into a new physical and chemical configuration. The high-pressure thus offers enhanced opportunities to discover new phases, both stable and metastable ones, and to tune exotic properties in a wide-range of atomistic length scale, substantially greater than (often being several orders of) those achieved by other thermal (varing temperatures) and chemical (varying composition or making alloys) means. Simple molecular solids like H{sub 2}, C, CO{sub 2}, N{sub 2}, O{sub 2}, H{sub 2}O, CO, NH{sub 3}, and CH{sub 4} are bounded by strong covalent intramolecular bonds, yet relatively weak intermolecular bonds of van der Waals and/or hydrogen bonds. The weak intermolecular bonds make these solids highly compressible (i.e., low bulk moduli typically less than 10 GPa), while the strong covalent bonds make them chemically inert at least initially at low pressures. Carboncarbon single bonds, carbon-oxygen double bonds and nitrogen-nitrogen triple bonds, for example, are among the strongest. These molecular forms are, thus, often considered to remain stable in an extended region of high pressures and high temperatures. High stabilities of these covalent molecules are also the basis of which their mixtures are often presumed to be the major detonation products of energetic materials as well as the major constituents of giant planets. However, their physical/chemical stabilities are not truly understood at those extreme pressure-temperature conditions. In fact, an increasing amount of experimental evidences contradict the assumed stability of these materials at high pressures and

  4. New Researches and Application Progress of Commonly Used Optical Molecular Imaging Technology

    PubMed Central

    Chen, Zhi-Yi; Yang, Feng; Lin, Yan; Zhou, Qiu-Lan; Liao, Yang-Ying

    2014-01-01

    Optical molecular imaging, a new medical imaging technique, is developed based on genomics, proteomics and modern optical imaging technique, characterized by non-invasiveness, non-radiativity, high cost-effectiveness, high resolution, high sensitivity and simple operation in comparison with conventional imaging modalities. Currently, it has become one of the most widely used molecular imaging techniques and has been applied in gene expression regulation and activity detection, biological development and cytological detection, drug research and development, pathogenesis research, pharmaceutical effect evaluation and therapeutic effect evaluation, and so forth, This paper will review the latest researches and application progresses of commonly used optical molecular imaging techniques such as bioluminescence imaging and fluorescence molecular imaging. PMID:24696850

  5. Web Service Access and Display of USGS Oceanographic Time-Series Data Using the NOAA Earth Research Division's Data Access Program (ERDDAP)

    NASA Astrophysics Data System (ADS)

    Montgomery, E. T.

    2008-12-01

    The sediment transport group of the U.S. Geologic Survey Coastal Marine Geology Program (USGS CMGP) maintains an archive of more than 4400 NetCDF files collected over the last 30 years (Montgomery et al, 2007). The conventions used in these NetCDF files were determined long before the emerging standard Climate and Forecast (CF) conventions for NetCDF, and web access has been traditionally been limited to simple downloading of the NetCDF files. To take advantage of a growing suite of software that works with CF-compliant data, A combination of NcML and the THREDDS Data Server were used to allow web services access of CF compliant data via the OGC WCS service and OPeNDAP. The primary users of these coastal oceanographic measurements are modelers who are facile with netCDF files and URL references. Other users, however, may prefer to obtain the data in another format or perhaps just plot a variable. To assist both groups of users, we have evaluated NOAA's Earth Research Division's Data Access Program (ERDDAP) as a potential method of providing a more flexible and powerful interface to the data. This versatile program is able to access data from a variety of web services, including OPeNDAP, and then deliver the data using web services in a very wide variety of formats, from common image formats such as PNG and JPG (pictures of plots), to NetCDF, Matlab, text and spreadsheet formats. Installation and configuration of ERDDAP was straightforward. The software written in Java, and delivered as a War file that runs on a standard Tomcat server. Configuration of the user interface and the dataset list is controlled by XML files. The documentation is well written and much of the XML generation is handled by the supplied autogen function that reads a netCDF file and generates XML based on the file attributes. We are working on a Matlab program that will completely automate the process by interrogating our data holdings and producing the completely formed XML. Our initial

  6. In vivo effects of microinjected alkaline phosphatase and its low molecular weight substrates on the first meiotic cell division in Xenopus laevis oocytes.

    PubMed Central

    Hermann, J; Mulner, O; Bellé, R; Marot, J; Tso, J; Ozon, R

    1984-01-01

    Xenopus laevis oocytes were microinjected with low molecular weight phosphoesters such as 2-glycerophosphate, phosphotyrosine, phosphoserine, phosphothreonine, 4-nitrophenyl phosphate, and orthophosphate. These compounds were able to induce a considerable reduction in the time course of progesterone-induced maturation, with 2-glycerophosphate being the most effective. The basal level of cAMP and its drop during maturation were not affected by the microinjection of 2-glycerophosphate. The injection of alkaline phosphatase (EC 3.1.3.1.) from calf intestine at a low concentration (10 ng per oocyte) was able to decrease or abolish the effect of 2-glycerophosphate. At higher concentration (25 ng per oocyte) this enzyme totally blocked progesterone- or maturation-promoting factor-induced maturation. Alkaline phosphatase might behave in vivo as a phosphoprotein phosphatase active towards phosphotyrosine-containing proteins. In addition, our results indicate that phosphate or phosphoester-containing buffers should be avoided in the course of maturation-promoting factor purification. PMID:6089179

  7. Asymmetric zygote division: A mystery starting point of embryogenesis.

    PubMed

    Zhao, Jing; Sun, Meng-Xiang

    2016-10-02

    In angiosperm, asymmetric zygote division is critical for embryogenesis. The molecular mechanism underlying this process has gained a great attention recently. Some players involve in the control of both accurate position and correct orientation of zygote division plane have been found, which provide useful clues for the extensive investigations. It is getting clear that both internal and external factors are involved in this complex regulatory mechanism and the asymmetric zygote division seems with great impact in cell fate determination and embryo pattern formation.

  8. [Molecular biological researches of the lower urinary tract function].

    PubMed

    Takeda, Masayuki; Araki, Isao

    2003-05-01

    Adrenergic alpha1 and beta receptors are present in the target organs of sympathetic nerve and they participate in the signal transduction mechanism of the lower urinary tract. Adrenergic alpha1 receptors are present in urethral and prostatic smooth muscles, and contract these muscles. Among these receptor subtypes, the alpha1-A receptor has the most important role, and mRNA expression of the corresponding alpha1-a subtype is predominant. In the human urinary bladder detrusor smooth muscle, the expression of adrenergic beta3 receptor subtype mRNA is predominant, and relaxation of detrusor smooth muscle is mediated mainly via beta3 receptor. Afferent nerve with lower threshold can easily transmit bladder sensation and takes an important role in the pathophysiology of urge urinary incontinence. Successful molecular cloning of vanilloid receptors, which are present in these afferent nerves, revealed that vanilloid receptors are ion-channels, sensitive for heat and pH, and termed VR1 and VRL1. Among purinergic receptors, ion channel type P2X3 receptor is found in afferent nerve fibers and plays some roles in the signal transduction of bladder sensation. In the near future, agonist for the adrenergic beta3 receptor and selective antagonists for VR1, VRL1, or P2X3 will possibly become drugs for pollakisuria and urge urinary incontinence.

  9. Physics Division annual report - 1998

    SciTech Connect

    1999-09-07

    Summaries are given of progress accomplished for the year in the following areas: (1) Heavy-Ion Nuclear Physics Research; (2) Operation and Development of Atlas; (3) Medium-Energy Nuclear Physics Research; (4) Theoretical Physics Research; and (5) Atomic and Molecular Physics Research.

  10. Earth Sciences Division collected abstracts: 1979

    SciTech Connect

    Henry, A.L.; Schwartz, L.L.

    1980-04-30

    This report is a compilation of abstracts of papers, internal reports, and talks presented during 1979 at national and international meetings by members of the Earth Sciences Division, Lawrence Livermore Laboratory. The arrangement is alphabetical (by author). For a given report, a bibliographic reference appears under the name of each coauthor, but the abstract iself is given only under the name of the first author or the first Earth Sciences Division author. A topical index at the end of the report provides useful cross references, while indicating major areas of research interest in the Earth Sciences Division.

  11. Asymmetric stem cell division: lessons from Drosophila.

    PubMed

    Wu, Pao-Shu; Egger, Boris; Brand, Andrea H

    2008-06-01

    Asymmetric cell division is an important and conserved strategy in the generation of cellular diversity during animal development. Many of our insights into the underlying mechanisms of asymmetric cell division have been gained from Drosophila, including the establishment of polarity, orientation of mitotic spindles and segregation of cell fate determinants. Recent studies are also beginning to reveal the connection between the misregulation of asymmetric cell division and cancer. What we are learning from Drosophila as a model system has implication both for stem cell biology and also cancer research.

  12. Cognitive and Neural Sciences Division 1990 Programs

    DTIC Science & Technology

    1990-08-01

    f D-/a33 773 ! COGNITIVE AND NEURAL SCIENCES -DIVISION 1990 PROGRAMS P .. i I’ • . M,’AR ’ OFFICE OF NAVAL RESEARCH 800 NORTH QUINCY STREET ARLINGTON... Cognitive and Neural Sciences Division 1990 Programs PE 61153N * 6. AUTHOR(S)I Edited by W-illard S. Vaughan 7. PERFORMING ORGANIZATION NAME(S) AND...NOTES This is a compilation of abstracts representing R&D sponsured by the ONR Cognitive and Neural Sciences Division. 12a. DISTRIBUTION AVAILABILITY

  13. Origin of life: Division for multiplication

    NASA Astrophysics Data System (ADS)

    Golestanian, Ramin

    2017-04-01

    Early forms of life could have started by molecular compounds coming together under conditions dense enough to promote reactions. But how might these droplets have undergone what we now know as cell division? The answer may be simpler than we think.

  14. Recent molecular genetic studies and methodological issues in suicide research.

    PubMed

    Tsai, Shih-Jen; Hong, Chen-Jee; Liou, Ying-Jay

    2011-06-01

    Suicide behavior (SB) spans a spectrum ranging from suicidal ideation to suicide attempts and completed suicide. Strong evidence suggests a genetic susceptibility to SB, including familial heritability and common occurrence in twins. This review addresses recent molecular genetic studies in SB that include case-control association, genome gene-expression microarray, and genome-wide association (GWA). This work also reviews epigenetics in SB and pharmacogenetic studies of antidepressant-induced suicide. SB fulfills criteria for a complex genetic phenotype in which environmental factors interact with multiple genes to influence susceptibility. So far, case-control association approaches are still the mainstream in SB genetic studies, although whole genome gene-expression microarray and GWA studies have begun to emerge in recent years. Genetic association studies have suggested several genes (e.g., serotonin transporter, tryptophan hydroxylase 2, and brain-derived neurotrophic factor) related to SB, but not all reports support these findings. The case-control approach while useful is limited by present knowledge of disease pathophysiology. Genome-wide studies of gene expression and genetic variation are not constrained by our limited knowledge. However, the explanatory power and path to clinical translation of risk estimates for common variants reported in genome-wide association studies remain unclear because of the presence of rare and structural genetic variation. As whole genome sequencing becomes increasingly widespread, available genomic information will no longer be the limiting factor in applying genetics to clinical medicine. These approaches provide exciting new avenues to identify new candidate genes for SB genetic studies. The other limitation of genetic association is the lack of a consistent definition of the SB phenotype among studies, an inconsistency that hampers the comparability of the studies and data pooling. In summary, SB involves multiple genes

  15. Training Program in the Molecular Basis of Breast Cancer Research

    DTIC Science & Technology

    1996-10-01

    Control with Cellular Stress Signals" "• Reception 3:30 p.m. - 4:30 p.m. Date: Friday, December 1, 1995 ,Organizer: Eva Lee, Ph.D. Place: Conference Room...34. * Reception 4:00 p.m. - 5:00 p.m. Thursday, February 8, 1996 Organizer: Alan Tomkinson Place: Conference Room 3.002 at the Institute of Biotechnology...Geoffrey Cooper, Dana-Farber Cancer Institute, Boston, MA 3:30 - 4:30 p.m. Reception Friday, April 5, 1996 Organizer: Ed Seto 1996 PORT ARANSAS RESEARCH

  16. The Need for Novel Informatics Tools for Integrating and Planning Research in Molecular and Cellular Cognition

    ERIC Educational Resources Information Center

    Silva, Alcino J.; Müller, Klaus-Robert

    2015-01-01

    The sheer volume and complexity of publications in the biological sciences are straining traditional approaches to research planning. Nowhere is this problem more serious than in molecular and cellular cognition, since in this neuroscience field, researchers routinely use approaches and information from a variety of areas in neuroscience and other…

  17. The role of research in molecular entomology in the fight against malaria vectors.

    PubMed

    della Torre, A; Arca, B; Favia, G; Petrarca, V; Coluzzi, M

    2008-06-01

    The text summarizes the principal current fields of investigation and the recent achievements of the research groups presently contributing to the Molecular Entomology Cluster of the Italian Malaria Network. Particular emphasis is given to the researches with a more direct impact on the fight against malaria vectors.

  18. The Need for Novel Informatics Tools for Integrating and Planning Research in Molecular and Cellular Cognition

    ERIC Educational Resources Information Center

    Silva, Alcino J.; Müller, Klaus-Robert

    2015-01-01

    The sheer volume and complexity of publications in the biological sciences are straining traditional approaches to research planning. Nowhere is this problem more serious than in molecular and cellular cognition, since in this neuroscience field, researchers routinely use approaches and information from a variety of areas in neuroscience and other…

  19. Global foot-and-mouth disease research update and gap analysis: 7 - pathogenesis and molecular biology

    USDA-ARS?s Scientific Manuscript database

    In 2014, the GFRA (Global Foot-and-mouth disease Research Alliance) conducted a gap analysis of FMD (Foot-and-Mouth Disease) research. This work has been updated and reported in a series of papers, in this article we report findings in the fields of 1) pathogenesis and 2) molecular biology. The arti...

  20. Oriented divisions, fate decisions

    PubMed Central

    Williams, Scott E.; Fuchs, Elaine

    2013-01-01

    During development, the establishment of proper tissue architecture depends upon the coordinated control of cell divisions not only in space and time, but also direction. Execution of an oriented cell division requires establishment of an axis of polarity and alignment of the mitotic spindle along this axis. Frequently, the cleavage plane also segregates fate determinants, either unequally or equally between daughter cells, the outcome of which is either an asymmetric or symmetric division, respectively. The last few years have witnessed tremendous growth in understanding both the extrinsic and intrinsic cues that position the mitotic spindle, the varied mechanisms in which the spindle orientation machinery is controlled in diverse organisms and organ systems, and the manner in which the division axis influences the signaling pathways that direct cell fate choices. PMID:24021274