Practical low-cost stereo head-mounted display

NASA Astrophysics Data System (ADS)

Pausch, Randy; Dwivedi, Pramod; Long, Allan C., Jr.

1991-08-01

A high-resolution head-mounted display has been developed from substantially cheaper components than previous systems. Monochrome displays provide 720 by 280 monochrome pixels to each eye in a one-inch-square region positioned approximately one inch from each eye. The display hardware is the Private Eye, manufactured by Reflection Technologies, Inc. The tracking system uses the Polhemus Isotrak, providing (x,y,z, azimuth, elevation and roll) information on the user''s head position and orientation 60 times per second. In combination with a modified Nintendo Power Glove, this system provides a full-functionality virtual reality/simulation system. Using two host 80386 computers, real-time wire frame images can be produced. Other virtual reality systems require roughly 250,000 in hardware, while this one requires only 5,000. Stereo is particularly useful for this system because shading or occlusion cannot be used as depth cues.

Visual cueing considerations in Nap-of-the-Earth helicopter flight head-slaved helmet-mounted displays

NASA Technical Reports Server (NTRS)

Grunwald, Arthur J.; Kohn, Silvia

1993-01-01

The pilot's ability to derive Control-Oriented Visual Field Information from teleoperated Helmet-Mounted displays in Nap-of-the-Earth flight, is investigated. The visual field with these types of displays, commonly used in Apache and Cobra helicopter night operations, originates from a relatively narrow field-of-view Forward Looking Infrared Radiation Camera, gimbal-mounted at the nose of the aircraft and slaved to the pilot's line-of-sight, in order to obtain a wide-angle field-of-regard. Pilots have encountered considerable difficulties in controlling the aircraft by these devices. Experimental simulator results presented here indicate that part of these difficulties can be attributed to head/camera slaving system phase lags and errors. In the presence of voluntary head rotation, these slaving system imperfections are shown to impair the Control-Oriented Visual Field Information vital in vehicular control, such as the perception of the anticipated flight path or the vehicle yaw rate. Since, in the presence of slaving system imperfections, the pilot will tend to minimize head rotation, the full wide-angle field-of-regard of the line-of-sight slaved Helmet-Mounted Display, is not always fully utilized.

Visual Simulation The Old Way

NASA Astrophysics Data System (ADS)

Gomes, Gary G.

1986-05-01

A cost effective and supportable color visual system has been developed to provide the necessary visual cues to United States Air Force B-52 bomber pilots training to become proficient at the task of inflight refueling. This camera model visual system approach is not suitable for all simulation applications, but provides a cost effective alternative to digital image generation systems when high fidelity of a single movable object is required. The system consists of a three axis gimballed KC-l35 tanker model, a range carriage mounted color augmented monochrome television camera, interface electronics, a color light valve projector and an infinity optics display system.

Simulator Study of Helmet-Mounted Symbology System Concepts in Degraded Visual Environments.

PubMed

Cheung, Bob; McKinley, Richard A; Steels, Brad; Sceviour, Robert; Cosman, Vaughn; Holst, Peter

2015-07-01

A sudden loss of external visual cues during critical phases of flight results in spatial disorientation. This is due to undetected horizontal and vertical drift when there is little tolerance for error and correction delay as the helicopter is close to the ground. Three helmet-mounted symbology system concepts were investigated in the simulator as potential solutions for the legacy Griffon helicopters. Thirteen Royal Canadian Air Force (RCAF) Griffon pilots were exposed to the Helmet Display Tracking System for Degraded Visual Environments (HDTS), the BrownOut Symbology System (BOSS), and the current RCAF AVS7 symbology system. For each symbology system, the pilot performed a two-stage departure and a single-stage approach. The presentation order of the symbology systems was randomized. Objective performance metrics included aircraft speed, altitude, attitude, and distance from the landing point. Subjective measurements included situation awareness, mental effort, perceived performance, perceptual cue rating, and NASA Task Load Index. Repeated measures analysis of variance and subsequent planned comparison for all the objective and subjective measurements were performed between the AVS7, HDTS, and BOSS. Our results demonstrated that HDTS and BOSS showed general improvement over AVS7 in two-stage departure. However, only HDTS performed significantly better in heading error than AVS7. During the single-stage approach, BOSS performed worse than AVS7 in heading root mean square error, and only HDTS performed significantly better in distance to landing point and approach heading than the others. Both the HDTS and BOSS possess their own limitations; however, HDTS is the pilots' preferred flight display.

Experiments in teleoperator and autonomous control of space robotic vehicles

NASA Technical Reports Server (NTRS)

Alexander, Harold L.

1991-01-01

A program of research embracing teleoperator and automatic navigational control of freely flying satellite robots is presented. Current research goals include: (1) developing visual operator interfaces for improved vehicle teleoperation; (2) determining the effects of different visual interface system designs on operator performance; and (3) achieving autonomous vision-based vehicle navigation and control. This research program combines virtual-environment teleoperation studies and neutral-buoyancy experiments using a space-robot simulator vehicle currently under development. Visual-interface design options under investigation include monoscopic versus stereoscopic displays and cameras, helmet-mounted versus panel-mounted display monitors, head-tracking versus fixed or manually steerable remote cameras, and the provision of vehicle-fixed visual cues, or markers, in the remote scene for improved sensing of vehicle position, orientation, and motion.

Ft. Hood iScout to Persistent Ground Surveillance System (PGSS) Cueing Demonstration

DTIC Science & Technology

2011-06-01

significantly as the team waited for the aerostat crew to finish their day’s testing. By the time the aerostat was moored on the trailer , it was moving about...maintained (figure 6). After looking over several movie clips, we drove back to the TOC to discuss emplacement strategy with Nibblett, who already had a...location would allow reception of signals from the Jalalabad sensors (figure 10). Figure 10. Mounting site for the repeater antenna on the

Motion parallax in immersive cylindrical display systems

NASA Astrophysics Data System (ADS)

Filliard, N.; Reymond, G.; Kemeny, A.; Berthoz, A.

2012-03-01

Motion parallax is a crucial visual cue produced by translations of the observer for the perception of depth and selfmotion. Therefore, tracking the observer viewpoint has become inevitable in immersive virtual (VR) reality systems (cylindrical screens, CAVE, head mounted displays) used e.g. in automotive industry (style reviews, architecture design, ergonomics studies) or in scientific studies of visual perception. The perception of a stable and rigid world requires that this visual cue be coherent with other extra-retinal (e.g. vestibular, kinesthetic) cues signaling ego-motion. Although world stability is never questioned in real world, rendering head coupled viewpoint in VR can lead to the perception of an illusory perception of unstable environments, unless a non-unity scale factor is applied on recorded head movements. Besides, cylindrical screens are usually used with static observers due to image distortions when rendering image for viewpoints different from a sweet spot. We developed a technique to compensate in real-time these non-linear visual distortions, in an industrial VR setup, based on a cylindrical screen projection system. Additionally, to evaluate the amount of discrepancies tolerated without perceptual distortions between visual and extraretinal cues, a "motion parallax gain" between the velocity of the observer's head and that of the virtual camera was introduced in this system. The influence of this artificial gain was measured on the gait stability of free-standing participants. Results indicate that, below unity, gains significantly alter postural control. Conversely, the influence of higher gains remains limited, suggesting a certain tolerance of observers to these conditions. Parallax gain amplification is therefore proposed as a possible solution to provide a wider exploration of space to users of immersive virtual reality systems.

A Molecular Code for Identity in the Vomeronasal System.

PubMed

Fu, Xiaoyan; Yan, Yuetian; Xu, Pei S; Geerlof-Vidavsky, Ilan; Chong, Wongi; Gross, Michael L; Holy, Timothy E

2015-10-08

In social interactions among mammals, individuals are recognized by olfactory cues, but identifying the key signals among thousands of compounds remains a major challenge. To address this need, we developed a new technique, component-activity matching (CAM), to select candidate ligands that "explain" patterns of bioactivity across diverse complex mixtures. Using mouse urine from eight different sexes and strains, we identified 23 components to explain firing rates in seven of eight functional classes of vomeronasal sensory neurons. Focusing on a class of neurons selective for females, we identified a novel family of vomeronasal ligands, steroid carboxylic acids. These ligands accounted for much of the neuronal activity of urine from some female strains, were necessary for normal levels of male investigatory behavior of female scents, and were sufficient to trigger mounting behavior. CAM represents the first step toward an exhaustive characterization of the molecular cues for natural behavior in a mammalian olfactory system. Copyright © 2015 Elsevier Inc. All rights reserved.

Re-Design and Beat Testing of the Man-Machine Integration Design and Analysis System: MIDAS

NASA Technical Reports Server (NTRS)

Shively, R. Jay; Rutkowski, Michael (Technical Monitor)

1999-01-01

The Man-machine Design and Analysis System (MIDAS) is a human factors design and analysis system that combines human cognitive models with 3D CAD models and rapid prototyping and simulation techniques. MIDAS allows designers to ask 'what if' types of questions early in concept exploration and development prior to actual hardware development. The system outputs predictions of operator workload, situational awareness and system performance as well as graphical visualization of the cockpit designs interacting with models of the human in a mission scenario. Recently, MIDAS was re-designed to enhance functionality and usability. The goals driving the redesign include more efficient processing, GUI interface, advances in the memory structures, implementation of external vision models and audition. These changes were detailed in an earlier paper. Two Beta test sites with diverse applications have been chosen. One Beta test site is investigating the development of a new airframe and its interaction with the air traffic management system. The second Beta test effort will investigate 3D auditory cueing in conjunction with traditional visual cueing strategies including panel-mounted and heads-up displays. The progress and lessons learned on each of these projects will be discussed.

The Human Retrosplenial Cortex and Thalamus Code Head Direction in a Global Reference Frame.

PubMed

Shine, Jonathan P; Valdés-Herrera, José P; Hegarty, Mary; Wolbers, Thomas

2016-06-15

Spatial navigation is a multisensory process involving integration of visual and body-based cues. In rodents, head direction (HD) cells, which are most abundant in the thalamus, integrate these cues to code facing direction. Human fMRI studies examining HD coding in virtual environments (VE) have reported effects in retrosplenial complex and (pre-)subiculum, but not the thalamus. Furthermore, HD coding appeared insensitive to global landmarks. These tasks, however, provided only visual cues for orientation, and attending to global landmarks did not benefit task performance. In the present study, participants explored a VE comprising four separate locales, surrounded by four global landmarks. To provide body-based cues, participants wore a head-mounted display so that physical rotations changed facing direction in the VE. During subsequent MRI scanning, subjects saw stationary views of the environment and judged whether their orientation was the same as in the preceding trial. Parameter estimates extracted from retrosplenial cortex and the thalamus revealed significantly reduced BOLD responses when HD was repeated. Moreover, consistent with rodent findings, the signal did not continue to adapt over repetitions of the same HD. These results were supported by a whole-brain analysis showing additional repetition suppression in the precuneus. Together, our findings suggest that: (1) consistent with the rodent literature, the human thalamus may integrate visual and body-based, orientation cues; (2) global reference frame cues can be used to integrate HD across separate individual locales; and (3) immersive training procedures providing full body-based cues may help to elucidate the neural mechanisms supporting spatial navigation. In rodents, head direction (HD) cells signal facing direction in the environment via increased firing when the animal assumes a certain orientation. Distinct brain regions, the retrosplenial cortex (RSC) and thalamus, code for visual and vestibular cues of orientation, respectively. Putative HD signals have been observed in human RSC but not the thalamus, potentially because body-based cues were not provided. Here, participants encoded HD in a novel virtual environment while wearing a head-mounted display to provide body-based cues for orientation. In subsequent fMRI scanning, we found evidence of an HD signal in RSC, thalamus, and precuneus. These findings harmonize rodent and human data, and suggest that immersive training procedures provide a viable way to examine the neural basis of navigation. Copyright © 2016 the authors 0270-6474/16/366371-11$15.00/0.

Multisensory cueing for enhancing orientation information during flight.

PubMed

Albery, William B

2007-05-01

The U.S. Air Force still regards spatial disorientation (SD) and loss of situational awareness (SA) as major contributing factors in operational Class A aircraft mishaps ($1M in aircraft loss and/or pilot fatality). Air Force Safety Agency data show 71 Class A SD mishaps from 1991-2004 in both fixed and rotary-wing aircraft. These mishaps resulted in 62 fatalities and an aircraft cost of over $2.OB. These losses account for 21 % of the USAF's Class A mishaps during that 14-yr period. Even non-mishap SD events negatively impact aircrew performance and reduce mission effectiveness. A multisensory system has been developed called the Spatial Orientation Retention Device (SORD) to enhance the aircraft attitude information to the pilot. SORD incorporates multisensory aids including helmet mounted symbology and tactile and audio cues. SORD has been prototyped and demonstrated in the Air Force Research Laboratory at Wright-Patterson AFB, OH. The technology has now been transitioned to a Rotary Wing Brownout program. This paper discusses the development of SORD and a potential application, including an augmented cognition application. Unlike automatic ground collision avoidance systems, SORD does not take over the aircraft if a pre-set altitude is broached by the pilot; rather, SORD provides complementary attitude cues to the pilot via the tactile, audio, and visual systems that allow the pilot to continue flying through disorienting conditions.

Multispectral image-fused head-tracked vision system (HTVS) for driving applications

NASA Astrophysics Data System (ADS)

Reese, Colin E.; Bender, Edward J.

2001-08-01

Current military thermal driver vision systems consist of a single Long Wave Infrared (LWIR) sensor mounted on a manually operated gimbal, which is normally locked forward during driving. The sensor video imagery is presented on a large area flat panel display for direct view. The Night Vision and Electronics Sensors Directorate and Kaiser Electronics are cooperatively working to develop a driver's Head Tracked Vision System (HTVS) which directs dual waveband sensors in a more natural head-slewed imaging mode. The HTVS consists of LWIR and image intensified sensors, a high-speed gimbal, a head mounted display, and a head tracker. The first prototype systems have been delivered and have undergone preliminary field trials to characterize the operational benefits of a head tracked sensor system for tactical military ground applications. This investigation will address the advantages of head tracked vs. fixed sensor systems regarding peripheral sightings of threats, road hazards, and nearby vehicles. An additional thrust will investigate the degree to which additive (A+B) fusion of LWIR and image intensified sensors enhances overall driving performance. Typically, LWIR sensors are better for detecting threats, while image intensified sensors provide more natural scene cues, such as shadows and texture. This investigation will examine the degree to which the fusion of these two sensors enhances the driver's overall situational awareness.

Falcons pursue prey using visual motion cues: new perspectives from animal-borne cameras

PubMed Central

Kane, Suzanne Amador; Zamani, Marjon

2014-01-01

This study reports on experiments on falcons wearing miniature videocameras mounted on their backs or heads while pursuing flying prey. Videos of hunts by a gyrfalcon (Falco rusticolus), gyrfalcon (F. rusticolus)/Saker falcon (F. cherrug) hybrids and peregrine falcons (F. peregrinus) were analyzed to determine apparent prey positions on their visual fields during pursuits. These video data were then interpreted using computer simulations of pursuit steering laws observed in insects and mammals. A comparison of the empirical and modeling data indicates that falcons use cues due to the apparent motion of prey on the falcon's visual field to track and capture flying prey via a form of motion camouflage. The falcons also were found to maintain their prey's image at visual angles consistent with using their shallow fovea. These results should prove relevant for understanding the co-evolution of pursuit and evasion, as well as the development of computer models of predation and the integration of sensory and locomotion systems in biomimetic robots. PMID:24431144

Falcons pursue prey using visual motion cues: new perspectives from animal-borne cameras.

PubMed

Kane, Suzanne Amador; Zamani, Marjon

2014-01-15

This study reports on experiments on falcons wearing miniature videocameras mounted on their backs or heads while pursuing flying prey. Videos of hunts by a gyrfalcon (Falco rusticolus), gyrfalcon (F. rusticolus)/Saker falcon (F. cherrug) hybrids and peregrine falcons (F. peregrinus) were analyzed to determine apparent prey positions on their visual fields during pursuits. These video data were then interpreted using computer simulations of pursuit steering laws observed in insects and mammals. A comparison of the empirical and modeling data indicates that falcons use cues due to the apparent motion of prey on the falcon's visual field to track and capture flying prey via a form of motion camouflage. The falcons also were found to maintain their prey's image at visual angles consistent with using their shallow fovea. These results should prove relevant for understanding the co-evolution of pursuit and evasion, as well as the development of computer models of predation and the integration of sensory and locomotion systems in biomimetic robots.

Depth Perception of Surgeons in Minimally Invasive Surgery.

PubMed

Bogdanova, Rositsa; Boulanger, Pierre; Zheng, Bin

2016-10-01

Minimally invasive surgery (MIS) poses visual challenges to the surgeons. In MIS, binocular disparity is not freely available for surgeons, who are required to mentally rebuild the 3-dimensional (3D) patient anatomy from a limited number of monoscopic visual cues. The insufficient depth cues from the MIS environment could cause surgeons to misjudge spatial depth, which could lead to performance errors thus jeopardizing patient safety. In this article, we will first discuss the natural human depth perception by exploring the main depth cues available for surgeons in open procedures. Subsequently, we will reveal what depth cues are lost in MIS and how surgeons compensate for the incomplete depth presentation. Next, we will further expand our knowledge by exploring some of the available solutions for improving depth presentation to surgeons. Here we will review the innovative approaches (multiple 2D camera assembly, shadow introduction) and devices (3D monitors, head-mounted devices, and auto-stereoscopic monitors) for 3D image presentation from the past few years. © The Author(s) 2016.

Effectiveness of basic display augmentation in vehicular control by visual field cues

NASA Technical Reports Server (NTRS)

Grunwald, A. J.; Merhav, S. J.

1978-01-01

The paper investigates the effectiveness of different basic display augmentation concepts - fixed reticle, velocity vector, and predicted future vehicle path - for RPVs controlled by a vehicle-mounted TV camera. The task is lateral manual control of a low flying RPV along a straight reference line in the presence of random side gusts. The man-machine system and the visual interface are modeled as a linear time-invariant system. Minimization of a quadratic performance criterion is assumed to underlie the control strategy of a well-trained human operator. The solution for the optimal feedback matrix enables the explicit computation of the variances of lateral deviation and directional error of the vehicle and of the control force that are used as performance measures.

Heeding the Voice of Experience: The Role of Talker Variation in Lexical Access

ERIC Educational Resources Information Center

Creel, Sarah C.; Aslin, Richard N.; Tanenhaus, Michael K.

2008-01-01

Two experiments used the head-mounted eye-tracking methodology to examine the time course of lexical activation in the face of a non-phonemic cue, talker variation. We found that lexical competition was attenuated by consistent talker differences between words that would otherwise be lexical competitors. In Experiment 1, some English cohort…

The moon illusion: a test of the vestibular hypothesis under monocular viewing conditions.

PubMed

Carter, D S

1977-12-01

The results of earlier monocular experiments on the moon illusion have been either negative or confounded. To test the role of vestibular function, 24 subjects made forced-choice distance comparisons between stimuli mounted in translucent tubes. The stimulus tube for standard distance could be positioned in three viewing angles (45 degrees up, horizontal, and 45 degrees down). A comparison tube adjustable for distance was mounted horizontally. There was a greater perception of depth in the downward looking condition. The relatively weak effects are discussed in terms of a two-hypothesis explanation of the real-life moon illusion and the poor cues for depth perception in monocular viewing.

In-Flight Study of Helmet-Mounted Symbology System Concepts in Degraded Visual Environments.

PubMed

Cheung, Bob; Craig, Gregory; Steels, Brad; Sceviour, Robert; Cosman, Vaughn; Jennings, Sion; Holst, Peter

2015-08-01

During approach and departure in rotary wing aircraft, a sudden loss of external visual reference precipitates spatial disorientation. There were 10 Royal Canadian Air Force (RCAF) Griffon pilots who participated in an in-flight investigation of a 3-dimensional conformal Helmet Display Tracking System (HDTS) and the BrownOut Symbology System (BOSS) aboard an Advanced System Research Aircraft. For each symbology system, pilots performed a two-stage departure followed by a single-stage approach. The presentation order of the two symbology systems was randomized across the pilots. Subjective measurements included situation awareness, mental effort, perceived performance, perceptual cue rating, NASA Task Load Index, and physiological response. Objective performance included aircraft speed, altitude, attitude, and distance from the landing point, control position, and control activity. Repeated measures analysis of variance and planned comparison tests for the subjective and objective responses were performed. For both maneuvers, the HDTS system afforded better situation awareness, lower workload, better perceptual cueing in attitude, horizontal and vertical translation, and lower overall workload index. During the two-stage departure, HDTS achieved less lateral drift from initial takeoff and hover, lower root mean square error (RMSE) in altitude during hover, and lower track error during the acceleration to forward flight. During the single-stage approach, HDTS achieved less error in lateral and longitudinal position offset from the landing point and lower RMSE in heading. In both maneuvers, pilots exhibited higher control activity when using HDTS, which suggested that more pertinent information was available to the pilots. Pilots preferred the HDTS system.

The evolutionary stability of attenuators that mask information about animals that social partners can exploit.

PubMed

Hackett, Sean; Ruxton, Graeme D

2018-05-01

Signals and cues are fundamental to social interactions. A well-established concept in the study of animal communication is an amplifier, defined as a trait that does not add extra information to that already present in the original cue or signal, but rather enhances the fidelity with which variation in the original cue or signal is correctly perceived. Attenuators as the logical compliment of amplifiers: attenuators act to reduce the fidelity with which variation in a signal or cue can be reliably evaluated by the perceivers. Where amplifiers reduce the effect of noise on the perception of variation, attenuators add noise. Attenuators have been subject to much less consideration than amplifiers; however, they will be the focus of our theoretical study. We utilize an extension of a well-established model incorporated signal or cue inaccuracy and costly investments by emitter and perceiver in sending and attending to the signal or cue. We present broad conditions involving some conflict of interest between emitter and perceiver where it may be advantageous for emitters to invest in costly attenuators to mask cues from potential perceivers, and a subset of these conditions where the perceiver may be willing to invest in costly anti-attenuators to mitigate the loss of information to them. We demonstrate that attenuators can be evolutionary stable even if they are costly, even if they are sometimes disadvantageous and even if a perceiver can mount counter-measures to them. As such, we feel that attenuators of cues may be deserving of much more research attention. © 2018 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2018 European Society For Evolutionary Biology.

Sensor-enhanced 3D conformal cueing for safe and reliable HC operation in DVE in all flight phases

NASA Astrophysics Data System (ADS)

Münsterer, Thomas; Schafhitzel, Tobias; Strobel, Michael; Völschow, Philipp; Klasen, Stephanus; Eisenkeil, Ferdinand

2014-06-01

Low level helicopter operations in Degraded Visual Environment (DVE) still are a major challenge and bear the risk of potentially fatal accidents. DVE generally encompasses all degradations to the visual perception of the pilot ranging from night conditions via rain and snowfall to fog and maybe even blinding sunlight or unstructured outside scenery. Each of these conditions reduce the pilots' ability to perceive visual cues in the outside world reducing his performance and finally increasing risk of mission failure and accidents, like for example Controlled Flight Into Terrain (CFIT). The basis for the presented solution is a fusion of processed and classified high resolution ladar data with database information having a potential to also include other sensor data like forward looking or 360° radar data. This paper reports on a pilot assistance system aiming at giving back the essential visual cues to the pilot by means of displaying 3D conformal cues and symbols in a head-tracked Helmet Mounted Display (HMD) and a combination with synthetic view on a head-down Multi-Function Display (MFD). Each flight phase and each flight envelope requires different symbology sets and different possibilities for the pilots to select specific support functions. Several functionalities have been implemented and tested in a simulator as well as in flight. The symbology ranges from obstacle warning symbology via terrain enhancements through grids or ridge lines to different waypoint symbols supporting navigation. While some adaptations can be automated it emerged as essential that symbology characteristics and completeness can be selected by the pilot to match the relevant flight envelope and outside visual conditions.

The Effects of Helmet-Mounted Display Symbology on the Opto-Kinetic Cervical Reflex and Frame of Reference

DTIC Science & Technology

2003-02-01

Ververs and Wickens, 1998; Wickens and Long, 1995; Yeh, Wickens, and Seagull , 1999) showed that some tasks do not allow for the near domain (symbology...Wickens, C. D., and Seagull , F. J. (1999). Target cueing in visual search: The effects of conformal and display location on the allocation of visual attention. Human Factors, 41(4), 524- 542.

Static and Motion-Based Visual Features Used by Airport Tower Controllers: Some Implications for the Design of Remote or Virtual Towers

NASA Technical Reports Server (NTRS)

Ellis, Stephen R.; Liston, Dorion B.

2011-01-01

Visual motion and other visual cues are used by tower controllers to provide important support for their control tasks at and near airports. These cues are particularly important for anticipated separation. Some of them, which we call visual features, have been identified from structured interviews and discussions with 24 active air traffic controllers or supervisors. The visual information that these features provide has been analyzed with respect to possible ways it could be presented at a remote tower that does not allow a direct view of the airport. Two types of remote towers are possible. One could be based on a plan-view, map-like computer-generated display of the airport and its immediate surroundings. An alternative would present a composite perspective view of the airport and its surroundings, possibly provided by an array of radially mounted cameras positioned at the airport in lieu of a tower. An initial more detailed analyses of one of the specific landing cues identified by the controllers, landing deceleration, is provided as a basis for evaluating how controllers might detect and use it. Understanding other such cues will help identify the information that may be degraded or lost in a remote or virtual tower not located at the airport. Some initial suggestions how some of the lost visual information may be presented in displays are mentioned. Many of the cues considered involve visual motion, though some important static cues are also discussed.

The influence of visual and vestibular orientation cues in a clock reading task.

PubMed

Davidenko, Nicolas; Cheong, Yeram; Waterman, Amanda; Smith, Jacob; Anderson, Barrett; Harmon, Sarah

2018-05-23

We investigated how performance in the real-life perceptual task of analog clock reading is influenced by the clock's orientation with respect to egocentric, gravitational, and visual-environmental reference frames. In Experiment 1, we designed a simple clock-reading task and found that observers' reaction time to correctly tell the time depends systematically on the clock's orientation. In Experiment 2, we dissociated egocentric from environmental reference frames by having participants sit upright or lie sideways while performing the task. We found that both reference frames substantially contribute to response times in this task. In Experiment 3, we placed upright or rotated participants in an upright or rotated immersive virtual environment, which allowed us to further dissociate vestibular from visual cues to the environmental reference frame. We found evidence of environmental reference frame effects only when visual and vestibular cues were aligned. We discuss the implications for the design of remote and head-mounted displays. Copyright © 2018 Elsevier Inc. All rights reserved.

Modeling Human Elements of Decision-Making

DTIC Science & Technology

2002-06-01

59 LIST OF REFERENCES Agor , Weston H ., The Logic of Intuitive Decision Making, Greenwood Press 1998 Barrick, M., Mount, M., "The Big Five...of sources discuss the concept of intuition. In The Logic of Intuitive Decision-making, Weston Agor refers to intuition as a highly rational...both factual and feeling 16 cues. Agor studied over 3000 individuals in leadership positions in a variety of organizations to determine the role

Claimed Versus Calculated Cue-Weighting Systems for Screening Employee Applicants

ERIC Educational Resources Information Center

Blevins, David E.

1975-01-01

This research compares the cue-weighting system which assessors claimed they used with the cue-weighting system one would infer they used based on multiple observations of their assessing behavior. The claimed cue-weighting systems agreed poorly with the empirically calculated cue-weighting systems for all assessors except one who utilized only…

The effects of motion and g-seat cues on pilot simulator performance of three piloting tasks

NASA Technical Reports Server (NTRS)

Showalter, T. W.; Parris, B. L.

1980-01-01

Data are presented that show the effects of motion system cues, g-seat cues, and pilot experience on pilot performance during takeoffs with engine failures, during in-flight precision turns, and during landings with wind shear. Eight groups of USAF pilots flew a simulated KC-135 using four different cueing systems. The basic cueing system was a fixed-base type (no-motion cueing) with visual cueing. The other three systems were produced by the presence of either a motion system or a g-seat, or both. Extensive statistical analysis of the data was performed and representative performance means were examined. These data show that the addition of motion system cueing results in significant improvement in pilot performance for all three tasks; however, the use of g-seat cueing, either alone or in conjunction with the motion system, provides little if any performance improvement for these tasks and for this aircraft type.

Spatio-temporal variation in click production rates of beaked whales: Implications for passive acoustic density estimation.

PubMed

Warren, Victoria E; Marques, Tiago A; Harris, Danielle; Thomas, Len; Tyack, Peter L; Aguilar de Soto, Natacha; Hickmott, Leigh S; Johnson, Mark P

2017-03-01

Passive acoustic monitoring has become an increasingly prevalent tool for estimating density of marine mammals, such as beaked whales, which vocalize often but are difficult to survey visually. Counts of acoustic cues (e.g., vocalizations), when corrected for detection probability, can be translated into animal density estimates by applying an individual cue production rate multiplier. It is essential to understand variation in these rates to avoid biased estimates. The most direct way to measure cue production rate is with animal-mounted acoustic recorders. This study utilized data from sound recording tags deployed on Blainville's (Mesoplodon densirostris, 19 deployments) and Cuvier's (Ziphius cavirostris, 16 deployments) beaked whales, in two locations per species, to explore spatial and temporal variation in click production rates. No spatial or temporal variation was detected within the average click production rate of Blainville's beaked whales when calculated over dive cycles (including silent periods between dives); however, spatial variation was detected when averaged only over vocal periods. Cuvier's beaked whales exhibited significant spatial and temporal variation in click production rates within vocal periods and when silent periods were included. This evidence of variation emphasizes the need to utilize appropriate cue production rates when estimating density from passive acoustic data.

Exploring virtual worlds with head-mounted displays

NASA Astrophysics Data System (ADS)

Chung, James C.; Harris, Mark R.; Brooks, F. P.; Fuchs, Henry; Kelley, Michael T.

1989-02-01

Research has been conducted in the use of simple head mounted displays in real world applications. Such units provide the user with non-holographic true 3-D information, since the kinetic depth effect, stereoscopy, and other visual cues combine to immerse the user in a virtual world which behaves like the real world in some respects. UNC's head mounted display was built inexpensively from commercially available off-the-shelf components. Tracking of the user's head position and orientation is performed by a Polhemus Navigation Sciences' 3SPACE tracker. The host computer uses the tracking information to generate updated images corresponding to the user's new left eye and right eye views. The images are broadcast to two liquid crystal television screens (220x320 pixels) mounted on a horizontal shelf at the user's forehead. The user views these color screens through half-silvered mirrors, enabling the computer generated image to be superimposed upon the user's real physical environment. The head mounted display was incorporated into existing molecular and architectural applications being developed at UNC. In molecular structure studies, chemists are presented with a room sized molecule with which they can interact in a manner more intuitive than that provided by conventional 2-D displays and dial boxes. Walking around and through the large molecule may provide quicker understanding of its structure, and such problems as drug enzyme docking may be approached with greater insight.

Wireless physiological monitoring and ocular tracking: 3D calibration in a fully-immersive virtual health care environment.

PubMed

Zhang, Lelin; Chi, Yu Mike; Edelstein, Eve; Schulze, Jurgen; Gramann, Klaus; Velasquez, Alvaro; Cauwenberghs, Gert; Macagno, Eduardo

2010-01-01

Wireless physiological/neurological monitoring in virtual reality (VR) offers a unique opportunity for unobtrusively quantifying human responses to precisely controlled and readily modulated VR representations of health care environments. Here we present such a wireless, light-weight head-mounted system for measuring electrooculogram (EOG) and electroencephalogram (EEG) activity in human subjects interacting with and navigating in the Calit2 StarCAVE, a five-sided immersive 3-D visualization VR environment. The system can be easily expanded to include other measurements, such as cardiac activity and galvanic skin responses. We demonstrate the capacity of the system to track focus of gaze in 3-D and report a novel calibration procedure for estimating eye movements from responses to the presentation of a set of dynamic visual cues in the StarCAVE. We discuss cyber and clinical applications that include a 3-D cursor for visual navigation in VR interactive environments, and the monitoring of neurological and ocular dysfunction in vision/attention disorders.

Augmented-reality visualization of brain structures with stereo and kinetic depth cues: system description and initial evaluation with head phantom

NASA Astrophysics Data System (ADS)

Maurer, Calvin R., Jr.; Sauer, Frank; Hu, Bo; Bascle, Benedicte; Geiger, Bernhard; Wenzel, Fabian; Recchi, Filippo; Rohlfing, Torsten; Brown, Christopher R.; Bakos, Robert J.; Maciunas, Robert J.; Bani-Hashemi, Ali R.

2001-05-01

We are developing a video see-through head-mounted display (HMD) augmented reality (AR) system for image-guided neurosurgical planning and navigation. The surgeon wears a HMD that presents him with the augmented stereo view. The HMD is custom fitted with two miniature color video cameras that capture a stereo view of the real-world scene. We are concentrating specifically at this point on cranial neurosurgery, so the images will be of the patient's head. A third video camera, operating in the near infrared, is also attached to the HMD and is used for head tracking. The pose (i.e., position and orientation) of the HMD is used to determine where to overlay anatomic structures segmented from preoperative tomographic images (e.g., CT, MR) on the intraoperative video images. Two SGI 540 Visual Workstation computers process the three video streams and render the augmented stereo views for display on the HMD. The AR system operates in real time at 30 frames/sec with a temporal latency of about three frames (100 ms) and zero relative lag between the virtual objects and the real-world scene. For an initial evaluation of the system, we created AR images using a head phantom with actual internal anatomic structures (segmented from CT and MR scans of a patient) realistically positioned inside the phantom. When using shaded renderings, many users had difficulty appreciating overlaid brain structures as being inside the head. When using wire frames, and texture-mapped dot patterns, most users correctly visualized brain anatomy as being internal and could generally appreciate spatial relationships among various objects. The 3D perception of these structures is based on both stereoscopic depth cues and kinetic depth cues, with the user looking at the head phantom from varying positions. The perception of the augmented visualization is natural and convincing. The brain structures appear rigidly anchored in the head, manifesting little or no apparent swimming or jitter. The initial evaluation of the system is encouraging, and we believe that AR visualization might become an important tool for image-guided neurosurgical planning and navigation.

Common software and interface for different helmet-mounted display (HMD) aircraft symbology sets

NASA Astrophysics Data System (ADS)

Mulholland, Fred F.

2000-06-01

Different aircraft in different services and countries have their own set of symbology they want displayed on their HMD. Even as flight symbolgy is standardized, there will still be some differences for types of aircraft, different weapons, different sensors, and different countries. As an HMD supplier, we want to provide a system that can be used across all these applications with no changes in the system, including no changes in the software. This HMD system must also provide the flexibility to accommodate new symbology as it is developed over the years, again, with no change in the HMD software. VSI has developed their HMD software to accommodate F-15, F- 16, F-18, and F-22 symbology sets for the Joint Helmet Mounted Cueing System. It also has the flexibility to accommodate the aircraft types and services of the Joint Strike Fighter: Conventional Takeoff and Landing variant for the USAF, Carrier-based Variant for the USN, and the Short Takeoff and Vertical Landing variant for the USMC and U.K. Royal Navy and Air Force. The key to this flexibility is the interface definition. The interface parameters are established at power-on with the download of an interface definition data set. This data set is used to interpret symbology commands from the aircraft OFP during operation and provide graphic commands to the HMD software. This presentation will define the graphics commands, provide an example of how the interface definition data set is defined, and then show how symbology commands produce a display.

Effects of Frame of Reference and Viewing Condition on Attentional Issues with Helmet Mounted Displays

DTIC Science & Technology

1998-01-01

monoscopically rather than only one, possibly due to the fact that the symbology was more intense when viewed with two eyes. Thus, subjects detected the...perceive the image with stereopsis depth cues. Applications for HMD technology range from the medical domain for the viewing of ultrasound data...its use must be considered within the context of the task; Dudfield, Hardiman, and Selcon (1995) warn of using decluttering in high workload

Developments in Human Centered Cueing Algorithms for Control of Flight Simulator Motion Systems

NASA Technical Reports Server (NTRS)

Houck, Jacob A.; Telban, Robert J.; Cardullo, Frank M.

1997-01-01

The authors conducted further research with cueing algorithms for control of flight simulator motion systems. A variation of the so-called optimal algorithm was formulated using simulated aircraft angular velocity input as a basis. Models of the human vestibular sensation system, i.e. the semicircular canals and otoliths, are incorporated within the algorithm. Comparisons of angular velocity cueing responses showed a significant improvement over a formulation using angular acceleration input. Results also compared favorably with the coordinated adaptive washout algorithm, yielding similar results for angular velocity cues while eliminating false cues and reducing the tilt rate for longitudinal cues. These results were confirmed in piloted tests on the current motion system at NASA-Langley, the Visual Motion Simulator (VMS). Proposed future developments by the authors in cueing algorithms are revealed. The new motion system, the Cockpit Motion Facility (CMF), where the final evaluation of the cueing algorithms will be conducted, is also described.

Decoupling analysis for a powertrain mounting system with a combination of hydraulic mounts

NASA Astrophysics Data System (ADS)

Hu, Jinfang; Chen, Wuwei; Huang, He

2013-07-01

The existing torque roll axis(TRA) decoupling theories for a powertrain mounting system assume that the stiffness and viscous damping properties are constant. However, real-life mounts exhibit considerable spectrally varying stiffness and damping characteristics, and the influence of the spectrally-varying properties of the hydraulic mounts on the powertrain system cannot be ignored. To overcome the deficiency, an analytical quasi-linear model of the hydraulic mount and the coupled properties of the powertrain and hydraulic mounts system are formulated. The influence of the hydraulic mounts on the TRA decoupling of a powertrain system is analytically examined in terms of eigensolutions, frequency, and impulse responses, and then a new analytical axiom is proposed based on the TRA decoupling indices. With the experimental setup of a fixed decoupler hydraulic mount in the context of non-resonant dynamic stiffness testing procedure, the quasi-linear model of the hydraulic mount is verified by comparing the predictions with the measurement. And the quasi-linear formulation of the coupled system is also verified by comparing the frequency responses with the numerical results obtained by the direct inversion method. Finally, the mounting system with a combination of hydraulic mounts is redesigned in terms of the stiffness, damping and mount locations by satisfying the new axiom. The frequency and time domain results of the redesigned system demonstrate that the torque roll axis of the redesigned powertrain mounting system is indeed decoupled in the presence of hydraulic mounts (given oscillating torque or impulsive torque excitation). The proposed research provides an important basis and method for the research on a powertrain system with spectrally-varying mount properties, especially for the TRA decoupling.

From cues to signals: evolution of interspecific communication via aposematism and mimicry in a predator-prey system.

PubMed

Lehmann, Kenna D S; Goldman, Brian W; Dworkin, Ian; Bryson, David M; Wagner, Aaron P

2014-01-01

Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment.

From Cues to Signals: Evolution of Interspecific Communication via Aposematism and Mimicry in a Predator-Prey System

PubMed Central

Lehmann, Kenna D. S.; Goldman, Brian W.; Dworkin, Ian; Bryson, David M.; Wagner, Aaron P.

2014-01-01

Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment. PMID:24614755

Call sign intelligibility improvement using a spatial auditory display

NASA Technical Reports Server (NTRS)

Begault, Durand R.

1994-01-01

A spatial auditory display was designed for separating the multiple communication channels usually heard over one ear to different virtual auditory positions. The single 19 foot rack mount device utilizes digital filtering algorithms to separate up to four communication channels. The filters use four different binaural transfer functions, synthesized from actual outer ear measurements, to impose localization cues on the incoming sound. Hardware design features include 'fail-safe' operation in the case of power loss, and microphone/headset interfaces to the mobile launch communication system in use at KSC. An experiment designed to verify the intelligibility advantage of the display used 130 different call signs taken from the communications protocol used at NASA KSC. A 6 to 7 dB intelligibility advantage was found when multiple channels were spatially displayed, compared to monaural listening. The findings suggest that the use of a spatial auditory display could enhance both occupational and operational safety and efficiency of NASA operations.

Automation in visual inspection tasks: X-ray luggage screening supported by a system of direct, indirect or adaptable cueing with low and high system reliability.

PubMed

Chavaillaz, Alain; Schwaninger, Adrian; Michel, Stefan; Sauer, Juergen

2018-05-25

The present study evaluated three automation modes for improving performance in an X-ray luggage screening task. 140 participants were asked to detect the presence of prohibited items in X-ray images of cabin luggage. Twenty participants conducted this task without automatic support (control group), whereas the others worked with either indirect cues (system indicated the target presence without specifying its location), or direct cues (system pointed out the exact target location) or adaptable automation (participants could freely choose between no cue, direct and indirect cues). Furthermore, automatic support reliability was manipulated (low vs. high). The results showed a clear advantage for direct cues regarding detection performance and response time. No benefits were observed for adaptable automation. Finally, high automation reliability led to better performance and higher operator trust. The findings overall confirmed that automatic support systems for luggage screening should be designed such that they provide direct, highly reliable cues.

Social orienting of children with autism to facial expressions and speech: a study with a wearable eye-tracker in naturalistic settings

PubMed Central

Magrelli, Silvia; Jermann, Patrick; Noris, Basilio; Ansermet, François; Hentsch, François; Nadel, Jacqueline; Billard, Aude

2013-01-01

This study investigates attention orienting to social stimuli in children with Autism Spectrum Conditions (ASC) during dyadic social interactions taking place in real-life settings. We study the effect of social cues that differ in complexity and distinguish between social cues produced by facial expressions of emotion and those produced during speech. We record the children's gazes using a head-mounted eye-tracking device and report on a detailed and quantitative analysis of the motion of the gaze in response to the social cues. The study encompasses a group of children with ASC from 2 to 11-years old (n = 14) and a group of typically developing (TD) children (n = 17) between 3 and 6-years old. While the two groups orient overtly to facial expressions, children with ASC do so to a lesser extent. Children with ASC differ importantly from TD children in the way they respond to speech cues, displaying little overt shifting of attention to speaking faces. When children with ASC orient to facial expressions, they show reaction times and first fixation lengths similar to those presented by TD children. However, children with ASC orient to speaking faces slower than TD children. These results support the hypothesis that individuals affected by ASC have difficulties processing complex social sounds and detecting intermodal correspondence between facial and vocal information. It also corroborates evidence that people with ASC show reduced overt attention toward social stimuli. PMID:24312064

Daytime Water Detection Based on Color Variation

NASA Technical Reports Server (NTRS)

Rankin, Arturo L.; Matthies, Larry H.

2010-01-01

Robust water detection is a critical perception requirement for unmanned ground vehicle (UGV) autonomous navigation. This is particularly true in wide open areas where water can collect in naturally occurring terrain depressions during periods of heavy precipitation and form large water bodies (such as ponds). At far range, reflections of the sky provide a strong cue for water. But at close range, the color coming out of a water body dominates sky reflections and the water cue from sky reflections is of marginal use. We model this behavior by using water body intensity data from multiple frames of RGB imagery to estimate the total reflection coefficient contribution from surface reflections and the combination of all other factors. Then we describe an algorithm that uses one of the color cameras in a forward- looking, UGV-mounted stereo-vision perception system to detect water bodies in wide open areas. This detector exploits the knowledge that the change in saturation-to-brightness ratio across a water body from the leading to trailing edge is uniform and distinct from other terrain types. In test sequences approaching a pond under clear, overcast, and cloudy sky conditions, the true positive and false negative water detection rates were (95.76%, 96.71%, 98.77%) and (0.45%, 0.60%, 0.62%), respectively. This software has been integrated on an experimental unmanned vehicle and field tested at Ft. Indiantown Gap, PA.

Receding and disparity cues aid relaxation of accommodation

PubMed Central

Horwood, Anna M; Riddell, Patricia M

2015-01-01

Purpose Accommodation can mask hyperopia and reduce the accuracy of non-cycloplegic refraction. It is therefore important to minimize accommodation to obtain as accurate a measure of hyperopia as possible. In order to characterize the parameters required to measure the maximally hyperopic error using photorefraction, we used different target types and distances to determine which target was most likely to maximally relax accommodation and thus more accurately detect hyperopia in an individual. Methods A PlusoptiX SO4 infra-red photorefractor was mounted in a remote haploscope which presented the targets. All participants were tested with targets at four fixation distances between 0.3m and 2m containing all combinations of blur, disparity and proximity/looming cues. 38 infants (6-44 wks) were studied longitudinally, and 104 children (4 -15 yrs (mean 6.4)) and 85 adults, with a range of refractive errors and binocular vision status, were tested once. Cycloplegic refraction data was available for a sub-set of 59 participants spread across the age range. Results The maximally hyperopic refraction (MHR) found at any time in the session was most frequently found when fixating the most distant targets and those containing disparity and dynamic proximity/looming cues. Presence or absence of blur was less significant, and targets in which only single cues to depth were present were also less likely to produce MHR. MHR correlated closely with cycloplegic refraction (r = 0.93,mean difference 0.07D,p=n.s.,95%CI ±<0.25D) after correction by a calibration factor. Conclusion Maximum relaxation of accommodation occurred for binocular targets receding into the distance. Proximal and disparity cues aid relaxation of accommodation to a greater extent than blur, and thus non-cycloplegic refraction targets should incorporate these cues. This is especially important in screening contexts with a brief opportunity to test for significant hyperopia. MHR in our laboratory was found to be a reliable estimation of cycloplegic refraction. PMID:19770814

Effects of visual and motion simulation cueing systems on pilot performance during takeoffs with engine failures

NASA Technical Reports Server (NTRS)

Parris, B. L.; Cook, A. M.

1978-01-01

Data are presented that show the effects of visual and motion during cueing on pilot performance during takeoffs with engine failures. Four groups of USAF pilots flew a simulated KC-135 using four different cueing systems. The most basic of these systems was of the instrument-only type. Visual scene simulation and/or motion simulation was added to produce the other systems. Learning curves, mean performance, and subjective data are examined. The results show that the addition of visual cueing results in significant improvement in pilot performance, but the combined use of visual and motion cueing results in far better performance.

Spatial awareness in immersive virtual environments revealed in open-loop walking

NASA Astrophysics Data System (ADS)

Turano, Kathleen A.; Chaudhury, Sidhartha

2005-03-01

People are able to walk without vision to previously viewed targets in the real world. This ability to update one"s position in space has been attributed to a path integration system that uses internally generated self-motion signals together with the perceived object-to-self distance of the target. In a previous study using an immersive virtual environment (VE), we found that many subjects were unable to walk without vision to a previously viewed target located 4 m away. Their walking paths were influenced by the room structure that varied trial to trial. In this study we investigated whether the phenomenon is specific to a VE by testing subjects in a real world and a VE. The real world was viewed with field restricting goggles and via cameras using the same head-mounted display as in the VE. The results showed that only in the VE were walking paths influenced by the room structure. Women were more affected than men, and the effect decreased over trials and after subjects performed the task in the real world. The results also showed that a brief (<0.5 s) exposure to the visual scene during self-motion was sufficient to reduce the influence of the room structure on walking paths. The results are consistent with the idea that without visual experience within the VE, the path integration system is unable to effectively update one"s spatial position. As a result, people rely on other cues to define their position in space. Women, unlike men, choose to use visual cues about environmental structure to reorient.

Solar panel truss mounting systems and methods

DOEpatents

Al-Haddad, Tristan Farris; Cavieres, Andres; Gentry, Russell; Goodman, Joseph; Nolan, Wade; Pitelka, Taylor; Rahimzadeh, Keyan; Brooks, Bradley; Lohr, Joshua; Crooks, Ryan; Porges, Jamie; Rubin, Daniel

2015-10-20

An exemplary embodiment of the present invention provides a solar panel truss mounting system comprising a base and a truss assembly coupled to the base. The truss assembly comprises a first panel rail mount, second panel rail mount parallel to the first panel rail mount, base rail mount parallel to the first and second panel rail mounts, and a plurality of support members. A first portion of the plurality of support members extends between the first and second panel rail mounts. A second portion of the plurality of support members extends between the first panel rail mount and the base rail mount. A third portion of the plurality of support members extends between the second panel rail mount and the base rail mount. The system can further comprise a plurality of connectors for coupling a plurality of photovoltaic solar panels to the truss assembly.

Solar panel truss mounting systems and methods

DOEpatents

Al-Haddad, Tristan Farris; Cavieres, Andres; Gentry, Russell; Goodman, Joseph; Nolan, Wade; Pitelka, Taylor; Rahimzadeh, Keyan; Brooks, Bradley; Lohr, Joshua; Crooks, Ryan; Porges, Jamie; Rubin, Daniel

2016-06-28

An exemplary embodiment of the present invention provides a solar panel truss mounting system comprising a base and a truss assembly coupled to the base. The truss assembly comprises a first panel rail mount, second panel rail mount parallel to the first panel rail mount, base rail mount parallel to the first and second panel rail mounts, and a plurality of support members. A first portion of the plurality of support members extends between the first and second panel rail mounts. A second portion of the plurality of support members extends between the first panel rail mount and the base rail mount. A third portion of the plurality of support members extends between the second panel rail mount and the base rail mount. The system can further comprise a plurality of connectors for coupling a plurality of photovoltaic solar panels to the truss assembly.

Neural substrates of smoking cue reactivity: A meta-analysis of fMRI studies

PubMed Central

Engelmann, Jeffrey M.; Versace, Francesco; Robinson, Jason D.; Minnix, Jennifer A.; Lam, Cho Y.; Cui, Yong; Brown, Victoria L.; Cinciripini, Paul M.

2012-01-01

Reactivity to smoking-related cues may be an important factor that precipitates relapse in smokers who are trying to quit. The neurobiology of smoking cue reactivity has been investigated in several fMRI studies. We combined the results of these studies using activation likelihood estimation, a meta-analytic technique for fMRI data. Results of the meta-analysis indicated that smoking cues reliably evoke larger fMRI responses than neutral cues in the extended visual system, precuneus, posterior cingulate gyrus, anterior cingulate gyrus, dorsal and medial prefrontal cortex, insula, and dorsal striatum. Subtraction meta-analyses revealed that parts of the extended visual system and dorsal prefrontal cortex are more reliably responsive to smoking cues in deprived smokers than in non-deprived smokers, and that short-duration cues presented in event-related designs produce larger responses in the extended visual system than long-duration cues presented in blocked designs. The areas that were found to be responsive to smoking cues agree with theories of the neurobiology of cue reactivity, with two exceptions. First, there was a reliable cue reactivity effect in the precuneus, which is not typically considered a brain region important to addiction. Second, we found no significant effect in the nucleus accumbens, an area that plays a critical role in addiction, but this effect may have been due to technical difficulties associated with measuring fMRI data in that region. The results of this meta-analysis suggest that the extended visual system should receive more attention in future studies of smoking cue reactivity. PMID:22206965

Mounting Systems for Structural Members, Fastening Assemblies Thereof, and Vibration Isolation Systems Including the Same

NASA Technical Reports Server (NTRS)

Young, Ken (Inventor); Hindle, Timothy (Inventor); Barber, Tim Daniel (Inventor)

2016-01-01

Mounting systems for structural members, fastening assemblies thereof, and vibration isolation systems including the same are provided. Mounting systems comprise a pair of mounting brackets, each clamped against a fastening assembly forming a mounting assembly. Fastening assemblies comprise a spherical rod end comprising a spherical member having a through opening and an integrally threaded shaft, first and second seating members on opposite sides of the spherical member and each having a through opening that is substantially coaxial with the spherical member through opening, and a partially threaded fastener that threadably engages each mounting bracket forming the mounting assembly. Structural members have axial end portions, each releasably coupled to a mounting bracket by the integrally threaded shaft. Axial end portions are threaded in opposite directions for permitting structural member rotation to adjust a length thereof to a substantially zero strain position. Structural members may be vibration isolator struts in vibration isolation systems.

Solar panel truss mounting systems and methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Haddad, Tristan Farris; Cavieres, Andres; Gentry, Russell

An exemplary embodiment of the present invention provides a solar panel truss mounting system comprising a base and a truss assembly coupled to the base. The truss assembly comprises a first panel rail mount, second panel rail mount parallel to the first panel rail mount, base rail mount parallel to the first and second panel rail mounts, and a plurality of support members. A first portion of the plurality of support members extends between the first and second panel rail mounts. A second portion of the plurality of support members extends between the first panel rail mount and the basemore » rail mount. A third portion of the plurality of support members extends between the second panel rail mount and the base rail mount. The system can further comprise a plurality of connectors for coupling a plurality of photovoltaic solar panels to the truss assembly.« less

Research on LQR optimal control method of active engine mount

NASA Astrophysics Data System (ADS)

Huan, Xie; Yu, Duan

2018-04-01

In this paper, the LQR control method is applied to the active mount of the engine, and a six-cylinder engine excitation model is established. Through the joint simulation of AMESim and MATLAB, the vibration isolation performance of the active mount system and the passive mount system is analyzed. Excited by the multi-engine operation, the simulation results of the vertical displacement, acceleration and dynamic deflection of the vehicle body show that the vibration isolation capability of the active mount system is superior to that of the passive mount system. It shows that compared with the passive mount, LQR active mount can greatly improve the vibration isolation performance, which proves the feasibility and effectiveness of the LQR control method.

Hyperstereopsis in night vision devices: basic mechanisms and impact for training requirements

NASA Astrophysics Data System (ADS)

Priot, Anne-Emmanuelle; Hourlier, Sylvain; Giraudet, Guillaume; Leger, Alain; Roumes, Corinne

2006-05-01

Including night vision capabilities in Helmet Mounted Displays has been a serious challenge for many years. The use of "see through" head mounted image intensifiers systems is particularly challenging as it introduces some peculiar visual characteristics usually referred as "hyperstereopsis". Flight testing of such systems has started in the early nineties, both in US and Europe. While the trials conducted in US yielded quite controversial results, convergent positive ones were obtained from European testing, mainly in UK, Germany and France. Subsequently, work on integrating optically coupled I2 tubes on HMD was discontinued in the US, while European manufacturers developed such HMDs for various rotary wings platforms like the TIGER. Coping with hyperstereopsis raises physiological and cognitive human factors issues. Starting in the sixties, effects of increased interocular separation and adaptation to such unusual vision conditions has been quite extensively studied by a number of authors as Wallach, Schor, Judge and Miles, Fisher and Ciuffreda. A synthetic review of literature on this subject will be presented. According to users' reports, three successive phases will be described for habituation to such devices: initial exposure, building compensation phase and behavioral adjustments phase. An habituation model will be suggested to account for HMSD users' reports and literature data bearing on hyperstereopsis, cue weighting for depth perception, adaptation and learning processes, task cognitive control. Finally, some preliminary results on hyperstereopsis spatial and temporal adaptation coming from the survey of training of TIGER pilots, currently conducted at the French-German Army Aviation Training Center, will be unveiled.

Methodology for the determination of criticality codes and recertification intervals for Tank Mounted Air Compressors (TMAC) and Base Mounted Air Compressors (BMAC)

NASA Technical Reports Server (NTRS)

Hargrove, William T.

1991-01-01

This methodology is used to determine inspection procedures and intervals for components contained within tank mounted air compressor systems (TMAC) and base mounted air compressor systems (BMAC). These systems are included in the Pressure Vessel and System Recertification inventory at GSFC.

Physical biology in cancer. 4. Physical cues guide tumor cell adhesion and migration.

PubMed

Stroka, Kimberly M; Konstantopoulos, Konstantinos

2014-01-15

As tumor cells metastasize from the primary tumor location to a distant secondary site, they encounter an array of biologically and physically heterogeneous microenvironments. While it is well established that biochemical signals guide all stages of the metastatic cascade, mounting evidence indicates that physical cues also direct tumor cell behavior, including adhesion and migration phenotypes. Physical cues acting on tumor cells in vivo include extracellular matrix mechanical properties, dimensionality, and topography, as well as interstitial flow, hydrodynamic shear stresses, and local forces due to neighboring cells. State-of-the-art technologies have recently enabled us and other researchers to engineer cell microenvironments that mimic specific physical properties of the cellular milieu. Through integration of these engineering strategies, along with physics, molecular biology, and imaging techniques, we have acquired new insights into tumor cell adhesion and migration mechanisms. In this review, we focus on the extravasation and invasion stages of the metastatic cascade. We first discuss the physical role of the endothelium during tumor cell extravasation and invasion and how contractility of endothelial and tumor cells contributes to the ability of tumor cells to exit the vasculature. Next, we examine how matrix dimensionality and stiffness coregulate tumor cell adhesion and migration beyond the vasculature. Finally, we summarize how tumor cells translate and respond to physical cues through mechanotransduction. Because of the critical role of tumor cell mechanotransduction at various stages of the metastatic cascade, targeting signaling pathways involved in tumor cell mechanosensing of physical stimuli may prove to be an effective therapeutic strategy for cancer patients.

Cue Reliability Represented in the Shape of Tuning Curves in the Owl's Sound Localization System

PubMed Central

Fischer, Brian J.; Peña, Jose L.

2016-01-01

Optimal use of sensory information requires that the brain estimates the reliability of sensory cues, but the neural correlate of cue reliability relevant for behavior is not well defined. Here, we addressed this issue by examining how the reliability of spatial cue influences neuronal responses and behavior in the owl's auditory system. We show that the firing rate and spatial selectivity changed with cue reliability due to the mechanisms generating the tuning to the sound localization cue. We found that the correlated variability among neurons strongly depended on the shape of the tuning curves. Finally, we demonstrated that the change in the neurons' selectivity was necessary and sufficient for a network of stochastic neurons to predict behavior when sensory cues were corrupted with noise. This study demonstrates that the shape of tuning curves can stand alone as a coding dimension of environmental statistics. SIGNIFICANCE STATEMENT In natural environments, sensory cues are often corrupted by noise and are therefore unreliable. To make the best decisions, the brain must estimate the degree to which a cue can be trusted. The behaviorally relevant neural correlates of cue reliability are debated. In this study, we used the barn owl's sound localization system to address this question. We demonstrated that the mechanisms that account for spatial selectivity also explained how neural responses changed with degraded signals. This allowed for the neurons' selectivity to capture cue reliability, influencing the population readout commanding the owl's sound-orienting behavior. PMID:26888922

Photovoltaic module mounting system

DOEpatents

Miros, Robert H. J.; Mittan, Margaret Birmingham; Seery, Martin N; Holland, Rodney H

2012-09-18

A solar array mounting system having unique installation, load distribution, and grounding features, and which is adaptable for mounting solar panels having no external frame. The solar array mounting system includes flexible, pedestal-style feet and structural links connected in a grid formation on the mounting surface. The photovoltaic modules are secured in place via the use of attachment clamps that grip the edge of the typically glass substrate. The panel mounting clamps are then held in place by tilt brackets and/or mid-link brackets that provide fixation for the clamps and align the solar panels at a tilt to the horizontal mounting surface. The tilt brackets are held in place atop the flexible feet and connected link members thus creating a complete mounting structure.

Photovoltaic module mounting system

DOEpatents

Miros, Robert H. J. [Fairfax, CA; Mittan, Margaret Birmingham [Oakland, CA; Seery, Martin N [San Rafael, CA; Holland, Rodney H [Novato, CA

2012-04-17

A solar array mounting system having unique installation, load distribution, and grounding features, and which is adaptable for mounting solar panels having no external frame. The solar array mounting system includes flexible, pedestal-style feet and structural links connected in a grid formation on the mounting surface. The photovoltaic modules are secured in place via the use of attachment clamps that grip the edge of the typically glass substrate. The panel mounting clamps are then held in place by tilt brackets and/or mid-link brackets that provide fixation for the clamps and align the solar panels at a tilt to the horizontal mounting surface. The tilt brackets are held in place atop the flexible feet and connected link members thus creating a complete mounting structure.

Role of Hypothalamic-Pituitary-Adrenal axis and corticotropin-releasing factor stress system on cue-induced relapse to alcohol seeking.

PubMed

Galesi, Fernanda L; Ayanwuyi, Lydia O; Mijares, Miriam Garcia; Cippitelli, Andrea; Cannella, Nazzareno; Ciccocioppo, Roberto; Ubaldi, Massimo

2016-10-05

A large body of evidence has shown that the Corticotropin Releasing Factor (CRF) system, which plays a key role in stress modulation, is deeply involved in relapse to alcohol seeking induced by exposure to stressful events such as foot shock or yohimbine injections. Exposure to environmental cues is also known to be a trigger for alcohol relapse, nevertheless, the relationship between the relapse evoked by the cue-induced model and the CRF stress systems remains unclear. The purpose of this study was to evaluate, in male Wistar rats, the involvement of the CRF system and Hypothalamic-Pituitary-Adrenal (HPA) axis in relapse induced by environmental cues. Antalarmin, a selective CRF1 receptor antagonist, Metyrapone, a corticosterone (CORT) synthesis inhibitor and CORT were evaluated for their effects on the reinstatement test in a cue-induced relapse model. Antalarmin (20mg/kg) blocked relapse to alcohol seeking induced by environmental cues. Metyrapone (50 and 100mg/kg) also blocked relapse in Wistar rats but only at the highest dose (100mg/kg). Corticosterone had no effect on relapse at the doses tested. The results obtained from this study suggest that the CRF stress system and the HPA axis are involved in cue-induced alcohol relapse. Copyright © 2016 Elsevier B.V. All rights reserved.

Fish predators reduce kelp frond loss via a trait-mediated trophic cascade.

PubMed

Haggerty, Miranda B; Anderson, Todd W; Long, Jeremy D

2018-05-05

Although trophic cascades were originally believed to be driven only by predators eating prey, there is mounting evidence that such cascades can be generated in large part via non-consumptive effects. This is especially important in cascades affecting habitat-forming foundation species that in turn, influence associated communities. Here, we use laboratory and field experiments to identify a trait-mediated indirect interaction between predators and an abundant kelp in a marine temperate reef system. Predation risk from a microcarnivorous fish, the señorita, suppressed grazing by the host-specific seaweed limpet, which in turn, influenced frond loss of the habitat-forming feather boa kelp. This trophic cascade was pronounced because minor amounts of limpet grazing decreased the strength required to break kelp fronds. Cues from fish predators mitigated kelp loss by decreasing limpet grazing; we found 86% of this indirect interaction between predator and kelp was attributed to the non-consumptive effect in the laboratory and 56% when applying the same effect size calculations to the field. In field manipulations, the non-consumptive effect of señorita was as strong as the total predator effect and most importantly, as strong as the uncaged, "open" treatment with natural levels of predators. Our findings demonstrate that the mere presence of this fish reduces frond loss of the feather boa kelp through a trait-mediated trophic cascade. Moreover, despite large volumes of water, current flow, and wave energy, we clearly demonstrate a strong non-consumptive effect via an apparent chemical cue from señorita, suggesting that chemically mediated trait-driven cascades may be more prevalent in subtidal marine systems than we are currently aware. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The Effect of Repeated Virtual Nicotine Cue Exposure Therapy on the Psychophysiological Responses: A Preliminary Study

PubMed Central

Choi, Jung-Seok; Park, Sumi; Lee, Jun-Young; Jung, Hee-Yeon; Lee, Hae-Woo; Jin, Chong-Hyeon

2011-01-01

Objective Smoking related cues may elicit smoking urges and psychophysiological responses in subjects with nicotine dependence. This study aimed to investigate the effect of repeated virtual cue exposure therapy using the surround-screen based projection wall system on the psychophysiological responses in nicotine dependence. Methods The authors developed 3-dimensional neutral and smoking-related environments using virtual reality (VR) technology. Smoking-related environment was a virtual bar, which comprised both object-related and social situation cues. Ten subjects with nicotine dependence participated in 4-week (one session per week) virtual cue exposure therapy. Psychophysiological responses [electromyography (EMG), skin conductance (SC), and heart rate] and subjective nicotine craving were acquired during each session. Results VR nicotine cue elicited greater psychophysiological responses and subjective craving for smoking than did neutral cue, and exposure to social situation cues showed greater psychophysiological responses in SC and EMG than did object-related cues. This responsiveness decreased during the course of repeated therapy. Conclusion The present study found that both psychophysiological responses and subjective nicotine craving were greater to nicotine cue exposure via projection wall VR system than to neutral cues and that enhanced cue reactivity decreased gradually over the course of repeated exposure therapy. These results suggest that VR cue exposure therapy combined with psychophysiological response monitoring may be an alternative treatment modality for smoking cessation, although the current findings are preliminary. PMID:21852993

Fractionating dead reckoning: role of the compass, odometer, logbook, and home base establishment in spatial orientation

NASA Astrophysics Data System (ADS)

Wallace, Douglas G.; Martin, Megan M.; Winter, Shawn S.

2008-06-01

Rats use multiple sources of information to maintain spatial orientation. Although previous work has focused on rats’ use of environmental cues, a growing number of studies have demonstrated that rats also use self-movement cues to organize navigation. This review examines the extent that kinematic analysis of naturally occurring behavior has provided insight into processes that mediate dead-reckoning-based navigation. This work supports a role for separate systems in processing self-movement cues that converge on the hippocampus. The compass system is involved in deriving directional information from self-movement cues; whereas, the odometer system is involved in deriving distance information from self-movement cues. The hippocampus functions similar to a logbook in that outward path unique information from the compass and odometer is used to derive the direction and distance of a path to the point at which movement was initiated. Finally, home base establishment may function to reset this system after each excursion and anchor environmental cues to self-movement cues. The combination of natural behaviors and kinematic analysis has proven to be a robust paradigm to investigate the neural basis of spatial orientation.

Fractionating dead reckoning: role of the compass, odometer, logbook, and home base establishment in spatial orientation

PubMed Central

Martin, Megan M.; Winter, Shawn S.

2008-01-01

Rats use multiple sources of information to maintain spatial orientation. Although previous work has focused on rats' use of environmental cues, a growing number of studies have demonstrated that rats also use self-movement cues to organize navigation. This review examines the extent that kinematic analysis of naturally occurring behavior has provided insight into processes that mediate dead-reckoning-based navigation. This work supports a role for separate systems in processing self-movement cues that converge on the hippocampus. The compass system is involved in deriving directional information from self-movement cues; whereas, the odometer system is involved in deriving distance information from self-movement cues. The hippocampus functions similar to a logbook in that outward path unique information from the compass and odometer is used to derive the direction and distance of a path to the point at which movement was initiated. Finally, home base establishment may function to reset this system after each excursion and anchor environmental cues to self-movement cues. The combination of natural behaviors and kinematic analysis has proven to be a robust paradigm to investigate the neural basis of spatial orientation. PMID:18553065

Virtual integral holography

NASA Astrophysics Data System (ADS)

Venolia, Dan S.; Williams, Lance

1990-08-01

A range of stereoscopic display technologies exist which are no more intrusive, to the user, than a pair of spectacles. Combining such a display system with sensors for the position and orientation of the user's point-of-view results in a greatly enhanced depiction of three-dimensional data. As the point of view changes, the stereo display channels are updated in real time. The face of a monitor or display screen becomes a window on a three-dimensional scene. Motion parallax naturally conveys the placement and relative depth of objects in the field of view. Most of the advantages of "head-mounted display" technology are achieved with a less cumbersome system. To derive the full benefits of stereo combined with motion parallax, both stereo channels must be updated in real time. This may limit the size and complexity of data bases which can be viewed on processors of modest resources, and restrict the use of additional three-dimensional cues, such as texture mapping, depth cueing, and hidden surface elimination. Effective use of "full 3D" may still be undertaken in a non-interactive mode. Integral composite holograms have often been advanced as a powerful 3D visualization tool. Such a hologram is typically produced from a film recording of an object on a turntable, or a computer animation of an object rotating about one axis. The individual frames of film are multiplexed, in a composite hologram, in such a way as to be indexed by viewing angle. The composite may be produced as a cylinder transparency, which provides a stereo view of the object as if enclosed within the cylinder, which can be viewed from any angle. No vertical parallax is usually provided (this would require increasing the dimensionality of the multiplexing scheme), but the three dimensional image is highly resolved and easy to view and interpret. Even a modest processor can duplicate the effect of such a precomputed display, provided sufficient memory and bus bandwidth. This paper describes the components of a stereo display system with user point-of-view tracking for interactive 3D, and a digital realization of integral composite display which we term virtual integral holography. The primary drawbacks of holographic display - film processing turnaround time, and the difficulties of displaying scenes in full color -are obviated, and motion parallax cues provide easy 3D interpretation even for users who cannot see in stereo.

Conveying facial expressions to blind and visually impaired persons through a wearable vibrotactile device.

PubMed

Buimer, Hendrik P; Bittner, Marian; Kostelijk, Tjerk; van der Geest, Thea M; Nemri, Abdellatif; van Wezel, Richard J A; Zhao, Yan

2018-01-01

In face-to-face social interactions, blind and visually impaired persons (VIPs) lack access to nonverbal cues like facial expressions, body posture, and gestures, which may lead to impaired interpersonal communication. In this study, a wearable sensory substitution device (SSD) consisting of a head mounted camera and a haptic belt was evaluated to determine whether vibrotactile cues around the waist could be used to convey facial expressions to users and whether such a device is desired by VIPs for use in daily living situations. Ten VIPs (mean age: 38.8, SD: 14.4) and 10 sighted persons (SPs) (mean age: 44.5, SD: 19.6) participated in the study, in which validated sets of pictures, silent videos, and videos with audio of facial expressions were presented to the participant. A control measurement was first performed to determine how accurately participants could identify facial expressions while relying on their functional senses. After a short training, participants were asked to determine facial expressions while wearing the emotion feedback system. VIPs using the device showed significant improvements in their ability to determine which facial expressions were shown. A significant increase in accuracy of 44.4% was found across all types of stimuli when comparing the scores of the control (mean±SEM: 35.0±2.5%) and supported (mean±SEM: 79.4±2.1%) phases. The greatest improvements achieved with the support of the SSD were found for silent stimuli (68.3% for pictures and 50.8% for silent videos). SPs also showed consistent, though not statistically significant, improvements while supported. Overall, our study shows that vibrotactile cues are well suited to convey facial expressions to VIPs in real-time. Participants became skilled with the device after a short training session. Further testing and development of the SSD is required to improve its accuracy and aesthetics for potential daily use.

Conveying facial expressions to blind and visually impaired persons through a wearable vibrotactile device

PubMed Central

Bittner, Marian; Kostelijk, Tjerk; van der Geest, Thea M.; Nemri, Abdellatif; van Wezel, Richard J. A.; Zhao, Yan

2018-01-01

In face-to-face social interactions, blind and visually impaired persons (VIPs) lack access to nonverbal cues like facial expressions, body posture, and gestures, which may lead to impaired interpersonal communication. In this study, a wearable sensory substitution device (SSD) consisting of a head mounted camera and a haptic belt was evaluated to determine whether vibrotactile cues around the waist could be used to convey facial expressions to users and whether such a device is desired by VIPs for use in daily living situations. Ten VIPs (mean age: 38.8, SD: 14.4) and 10 sighted persons (SPs) (mean age: 44.5, SD: 19.6) participated in the study, in which validated sets of pictures, silent videos, and videos with audio of facial expressions were presented to the participant. A control measurement was first performed to determine how accurately participants could identify facial expressions while relying on their functional senses. After a short training, participants were asked to determine facial expressions while wearing the emotion feedback system. VIPs using the device showed significant improvements in their ability to determine which facial expressions were shown. A significant increase in accuracy of 44.4% was found across all types of stimuli when comparing the scores of the control (mean±SEM: 35.0±2.5%) and supported (mean±SEM: 79.4±2.1%) phases. The greatest improvements achieved with the support of the SSD were found for silent stimuli (68.3% for pictures and 50.8% for silent videos). SPs also showed consistent, though not statistically significant, improvements while supported. Overall, our study shows that vibrotactile cues are well suited to convey facial expressions to VIPs in real-time. Participants became skilled with the device after a short training session. Further testing and development of the SSD is required to improve its accuracy and aesthetics for potential daily use. PMID:29584738

Orexin-1 receptor signaling increases motivation for cocaine-associated cues

PubMed Central

Bentzley, Brandon S.; Aston-Jones, Gary

2015-01-01

The orexin/hypocretin system is involved in multiple cocaine addiction processes that involve drug-associated environmental cues, including cue-induced reinstatement of extinguished cocaine seeking and expression of conditioned place preference. However, the orexin system does not play a role in several behaviors that are less cue-dependent, such as cocaine-primed reinstatement of extinguished cocaine seeking and low-effort cocaine self-administration. We hypothesized that cocaine-associated cues, but not cocaine alone, engage signaling at orexin-1 receptors (OX1R), and this cue-engaged OX1R signaling increases motivation for cocaine. Motivation for cocaine was measured in Sprague-Dawley rats with behavioral-economic demand curve analysis after pretreatment with the OX1R antagonist SB-334867 (SB) or vehicle with and without light+tone cues. Demand for cocaine was higher when cocaine-associated cues were present, and SB only reduced cocaine demand in the presence of these cues. We then asked if cocaine demand is linked to cued-reinstatement of cocaine seeking, as both procedures are partially driven by cocaine-associated cues in an orexin-dependent manner. SB blocked cue-induced reinstatement behavior, and baseline demand predicted SB efficacy with the largest effect in high demand animals, i.e., animals with the greatest cue-dependent behavior. We conclude that OX1R signaling increases the reinforcing efficacy of cocaine-associated cues but not for cocaine alone. This supports our view that orexin plays a prominent role in the ability of conditioned cues to activate motivational responses. PMID:25754681

Excitotoxic lesions of the infralimbic, but not prelimbic cortex facilitate reversal of appetitive discriminative context conditioning: the role of the infralimbic cortex in context generalization

PubMed Central

Ashwell, Rachel; Ito, Rutsuko

2014-01-01

The prelimbic and infralimbic regions of the rat medial prefrontal cortex (mPFC) are important components of the limbic cortico-striatal circuit, receiving converging projections from the hippocampus (HPC) and amygdala. Mounting evidence points to these regions having opposing roles in the regulation of the expression of contextual fear and context-induced cocaine-seeking. To investigate this functional differentiation in motivated behavior further, this study employed a novel radial maze task previously shown to be dependent on the integrity of the hippocampus and its functional connection to the nucleus accumbens (NAc) shell, to investigate the effects of selective excitotoxic lesions of the prelimbic (PL) and infralimbic (IL) upon the spatial contextual control over reward learning. To this end, rats were trained to develop discriminative responding towards a reward-associated discrete cue presented in three out of six spatial locations (3 arms out of 6 radial maze arms), and to avoid the same discrete cue presented in the other three spatial locations. Once acquired, the reward contingencies of the spatial locations were reversed, such that responding to the cue presented in a previously rewarded location was no longer rewarded. Furthermore, the acquisition of spatial learning was probed separately using conditioned place preference (CPP) and the monitoring of arm selection at the beginning of each training session. Lesions of the PL transiently attenuated the acquisition of the initial cue approach training and spatial learning, while leaving reversal learning intact. In contrast, IL lesions led to a significantly superior performance of spatial context-dependent discriminative cue approach and reversal learning, in the absence of a significant preference for the new reward-associated spatial locations. These results indicate that the PL and IL have functionally dissociative, and potentially opposite roles in the regulation of spatial contextual control over appetitive learning. PMID:24616678

F-16 Task Analysis Criterion-Referenced Objective and Objectives Hierarchy Report. Volume 4

DTIC Science & Technology

1981-03-01

Initiation cues: Engine flameout Systems presenting cues: Aircraft fuel, engine STANDARD: Authority: TACR 60-2 Performance precision: TD in first 1/3 of...task: None Initiation cues: On short final Systems preventing cues: N/A STANDARD: Authority: 60-2 Performance precision: +/- .5 AOA; TD zone 150-1000...precision: +/- .05 AOA; TD Zone 150-1000 Computational accuracy: N/A ... . . ... . ... e e m I TASK NO.: 1.9.4 BEHAVIOR: Perform short field landing

Cue Reliability Represented in the Shape of Tuning Curves in the Owl's Sound Localization System.

PubMed

Cazettes, Fanny; Fischer, Brian J; Peña, Jose L

2016-02-17

Optimal use of sensory information requires that the brain estimates the reliability of sensory cues, but the neural correlate of cue reliability relevant for behavior is not well defined. Here, we addressed this issue by examining how the reliability of spatial cue influences neuronal responses and behavior in the owl's auditory system. We show that the firing rate and spatial selectivity changed with cue reliability due to the mechanisms generating the tuning to the sound localization cue. We found that the correlated variability among neurons strongly depended on the shape of the tuning curves. Finally, we demonstrated that the change in the neurons' selectivity was necessary and sufficient for a network of stochastic neurons to predict behavior when sensory cues were corrupted with noise. This study demonstrates that the shape of tuning curves can stand alone as a coding dimension of environmental statistics. In natural environments, sensory cues are often corrupted by noise and are therefore unreliable. To make the best decisions, the brain must estimate the degree to which a cue can be trusted. The behaviorally relevant neural correlates of cue reliability are debated. In this study, we used the barn owl's sound localization system to address this question. We demonstrated that the mechanisms that account for spatial selectivity also explained how neural responses changed with degraded signals. This allowed for the neurons' selectivity to capture cue reliability, influencing the population readout commanding the owl's sound-orienting behavior. Copyright © 2016 the authors 0270-6474/16/362101-10$15.00/0.

Design and vibration control of vehicle engine mount activated by MR fluid and piezoelectric actuator

NASA Astrophysics Data System (ADS)

Lee, D. Y.; Park, Y. K.; Choi, S. B.; Lee, H. G.

2009-07-01

An engine is one of the most dominant noise and vibration sources in vehicle systems. Therefore, in order to resolve noise and vibration problems due to engine, various types of engine mounts have been proposed. This work presents a new type of active engine mount system featuring a magneto-rheological (MR) fluid and a piezostack actuator. As a first step, six degrees-of freedom dynamic model of an in-line four-cylinder engine which has three points mounting system is derived by considering the dynamic behaviors of MR mount and piezostack mount. In the configuration of engine mount system, two MR mounts are installed for vibration control of roll mode motion whose energy is very high in low frequency range, while one piezostack mount is installed for vibration control of bounce and pitch mode motion whose energy is relatively high in high frequency range. As a second step, linear quadratic regulator (LQR) controller is synthesized to actively control the imposed vibration. In order to demonstrate the effectiveness of the proposed active engine mount, vibration control performances are evaluated under various engine operating speeds (wide frequency range).

Near-optimal integration of facial form and motion.

PubMed

Dobs, Katharina; Ma, Wei Ji; Reddy, Leila

2017-09-08

Human perception consists of the continuous integration of sensory cues pertaining to the same object. While it has been fairly well shown that humans use an optimal strategy when integrating low-level cues proportional to their relative reliability, the integration processes underlying high-level perception are much less understood. Here we investigate cue integration in a complex high-level perceptual system, the human face processing system. We tested cue integration of facial form and motion in an identity categorization task and found that an optimal model could successfully predict subjects' identity choices. Our results suggest that optimal cue integration may be implemented across different levels of the visual processing hierarchy.

Candidate configuration trade study, Stellar-inertial Measurement Systems (SIMS) for an Earth Observation Satellite (EOS)

NASA Technical Reports Server (NTRS)

Ogletree, G.; Coccoli, J.; Mckern, R.; Smith, M.; White, R.

1972-01-01

The results of analytical and simulation studies of the stellar-inertial measurement system (SIMS) for an earth observation satellite are presented. Subsystem design analyses and sensor design trades are reported. Three candidate systems are considered: (1) structure-mounted gyros with structure-mounted star mapper, (2) structure-mounted gyros with gimbaled star tracker, and (3) gimbaled gyros with structure-mounted star mapper. The purpose of the study is to facilitate the decisions pertaining to gimbaled versus structure-mounted gyros and star sensors, and combinations of systems suitable for the EOS satellite.

Cannabis cue-elicited craving and the reward neurocircuitry.

PubMed

Filbey, Francesca M; DeWitt, Samuel J

2012-07-02

Cue-elicited craving or the intense desire to consume a substance following exposure to a conditioned drug cue is one of the primary behavioral symptoms of substance use disorders (SUDs). While the concept of cue-elicited craving is well characterized in alcohol and other substances of abuse, only recently has it been described in cannabis. A review of the extant literature has established that cue-elicited craving is a powerful reinforcer that contributes to drug-seeking for cannabis. Further, emergent research has begun to identify the neurobiological systems and neural mechanisms associated with this behavior. What research shows is that while theories of THC's effects on the dopaminergic-reward system remain divergent, cannabis cues elicit neural activation in the brain's reward network. Copyright © 2011 Elsevier Inc. All rights reserved.

Repeated Alcohol Extinction Sessions in Conjunction with MK-801, but not Yohimbine or Propranolol, Reduces Subsequent Alcohol Cue-Induced Responding in Rats

PubMed Central

Williams, Keith L.; Harding, Kaitlyn M.

2014-01-01

Cues associated with alcohol can stimulate subjective states that increase relapse. Alcohol-cue associations may be strengthened by enhancing adrenergic activity with yohimbine or weakened by blocking adrenergic activity with propranolol. Alcohol-cue associations may also be weakened by long cue exposure sessions or strengthened by short cue exposure sessions. A useful treatment approach for alcoholism may combine adrenergic manipulation with cue exposure sessions of a specific duration. The present study sought to determine if cue exposure during long- or short-duration extinction sessions with post-session yohimbine or propranolol would alter alcohol cue-induced responding and self-administration. Rats were trained to respond for alcohol during sessions that included an olfactory cue given at the beginning of the session and a visual/auditory cue complex delivered concurrently with alcohol. Cue-induced responding was assessed before and after the repeated extinction sessions. Repeated alcohol extinction sessions of long duration (45 min) or short duration (5 min) were followed immediately by injections of saline, yohimbine, or propranolol. After the second set of cue-induced responding tests, reacquisition of operant alcohol self-administration was examined. To determine if the experimental procedures were sensitive to memory manipulation through other pharmacological mechanisms, the NMDA receptor antagonist MK-801 was given 20 min prior to long-duration extinction sessions. Both the long- and short-duration extinction sessions decreased cue-induced responding. Neither yohimbine nor propranolol, given post-session, had subsequent effects on cue-induced responding or alcohol self-administration. MK-801 blocked the effect of extinction sessions on cue-induced responding but had no effect on self-administration. The present study shows that manipulation of the NMDA system in combination with alcohol cue exposure therapy during extinction-like sessions may be more effective than manipulation of the adrenergic system in reducing the strength of alcohol-cue associations in this specific model of alcohol relapse. PMID:24269546

Static Performance of a Wing-Mounted Thrust Reverser Concept

NASA Technical Reports Server (NTRS)

Asbury, Scott C.; Yetter, Jeffrey A.

1998-01-01

An experimental investigation was conducted in the Jet-Exit Test Facility at NASA Langley Research Center to study the static aerodynamic performance of a wing-mounted thrust reverser concept applicable to subsonic transport aircraft. This innovative engine powered thrust reverser system is designed to utilize wing-mounted flow deflectors to produce aircraft deceleration forces. Testing was conducted using a 7.9%-scale exhaust system model with a fan-to-core bypass ratio of approximately 9.0, a supercritical left-hand wing section attached via a pylon, and wing-mounted flow deflectors attached to the wing section. Geometric variations of key design parameters investigated for the wing-mounted thrust reverser concept included flow deflector angle and chord length, deflector edge fences, and the yaw mount angle of the deflector system (normal to the engine centerline or parallel to the wing trailing edge). All tests were conducted with no external flow and high pressure air was used to simulate core and fan engine exhaust flows. Test results indicate that the wing-mounted thrust reverser concept can achieve overall thrust reverser effectiveness levels competitive with (parallel mount), or better than (normal mount) a conventional cascade thrust reverser system. By removing the thrust reverser system from the nacelle, the wing-mounted concept offers the nacelle designer more options for improving nacelle aero dynamics and propulsion-airframe integration, simplifying nacelle structural designs, reducing nacelle weight, and improving engine maintenance access.

The Influence of Loss of Visual Cues on Pilot Performance During the Final Approach and Landing Phase of a Remotely Piloted Vehicle Mission

NASA Technical Reports Server (NTRS)

Howard, James C.

1976-01-01

Remotely piloted research vehicles (RPRVS) are currently being flown from fixed-base control centers, and visual information is supplied to the remote pilot by a TV camera mounted in the vehicle. In these circumstances, the possibility of a TV failure or an interruption in the downlink to the pilot must be considered. To determine the influence of loss of TV information on pilot performance during the final approach and landing phase of a mission, an experiment was conducted in which pilots were asked to fly a fixed-base simulation of a Piper PA-30 aircraft with loss of TV information occurring at altitudes of 15.24, 30.48, and 45.72 m (50, 100, and 150 ft). For this experiment, a specially designed display configuration was presented to four pilots in accordance with a Latin square design. Initial results indicate that pilots could not ensure successful landings from altitudes exceeding 15.24 m (.50 ft) without the visual cues supplied by the TV picture.

Mental Effort in Binary Categorization Aided by Binary Cues

ERIC Educational Resources Information Center

Botzer, Assaf; Meyer, Joachim; Parmet, Yisrael

2013-01-01

Binary cueing systems assist in many tasks, often alerting people about potential hazards (such as alarms and alerts). We investigate whether cues, besides possibly improving decision accuracy, also affect the effort users invest in tasks and whether the required effort in tasks affects the responses to cues. We developed a novel experimental tool…

Algorithm for Simulating Atmospheric Turbulence and Aeroelastic Effects on Simulator Motion Systems

NASA Technical Reports Server (NTRS)

Ercole, Anthony V.; Cardullo, Frank M.; Kelly, Lon C.; Houck, Jacob A.

2012-01-01

Atmospheric turbulence produces high frequency accelerations in aircraft, typically greater than the response to pilot input. Motion system equipped flight simulators must present cues representative of the aircraft response to turbulence in order to maintain the integrity of the simulation. Currently, turbulence motion cueing produced by flight simulator motion systems has been less than satisfactory because the turbulence profiles have been attenuated by the motion cueing algorithms. This report presents a new turbulence motion cueing algorithm, referred to as the augmented turbulence channel. Like the previous turbulence algorithms, the output of the channel only augments the vertical degree of freedom of motion. This algorithm employs a parallel aircraft model and an optional high bandwidth cueing filter. Simulation of aeroelastic effects is also an area where frequency content must be preserved by the cueing algorithm. The current aeroelastic implementation uses a similar secondary channel that supplements the primary motion cue. Two studies were conducted using the NASA Langley Visual Motion Simulator and Cockpit Motion Facility to evaluate the effect of the turbulence channel and aeroelastic model on pilot control input. Results indicate that the pilot is better correlated with the aircraft response, when the augmented channel is in place.

Naloxone injections into CA3 disrupt pattern completion associated with relapse from cocaine seeking

PubMed Central

Kirk, Ryan A.; Clark, Jascha K.; Moore, Angela; Keefe, Kristen

2016-01-01

The goal of the present research was to assess the degree to which a pattern completion process operates in cue-induced relapse to cocaine-seeking behavior. Using a novel cue-preference version of the place preference task, rats were administered cocaine or saline, which resulted in a preference for the cocaine-paired cues. After 21 days of abstinence and prior to the preference test, for one group, PBS or naloxone was injected into the CA3 subregion of the hippocampus and for a second group, saline or naloxone was injected systemically. The results indicated that infusions of naloxone into CA3 or systemic injections produced a marked disruption for one and two cues, but had minimal disruptive effect for three or four cues, suggesting that naloxone injections disrupt CA3 function and trigger a deficit in a pattern completion process. Thus, it appears that cue-based activation of the dorsal CA3 might be a critical trigger via a pattern completion process. Based on additional analyses it appears that there is a disruption primarily for object touches for one cue naloxone injections into the CA3 or systemic injections, but no effect on time (spatial context). PMID:26815290

Cortical cholinergic signaling controls the detection of cues

PubMed Central

Gritton, Howard J.; Howe, William M.; Mallory, Caitlin S.; Hetrick, Vaughn L.; Berke, Joshua D.; Sarter, Martin

2016-01-01

The cortical cholinergic input system has been described as a neuromodulator system that influences broadly defined behavioral and brain states. The discovery of phasic, trial-based increases in extracellular choline (transients), resulting from the hydrolysis of newly released acetylcholine (ACh), in the cortex of animals reporting the presence of cues suggests that ACh may have a more specialized role in cognitive processes. Here we expressed channelrhodopsin or halorhodopsin in basal forebrain cholinergic neurons of mice with optic fibers directed into this region and prefrontal cortex. Cholinergic transients, evoked in accordance with photostimulation parameters determined in vivo, were generated in mice performing a task necessitating the reporting of cue and noncue events. Generating cholinergic transients in conjunction with cues enhanced cue detection rates. Moreover, generating transients in noncued trials, where cholinergic transients normally are not observed, increased the number of invalid claims for cues. Enhancing hits and generating false alarms both scaled with stimulation intensity. Suppression of endogenous cholinergic activity during cued trials reduced hit rates. Cholinergic transients may be essential for synchronizing cortical neuronal output driven by salient cues and executing cue-guided responses. PMID:26787867

Open Platform for Limit Protection with Carefree Maneuver Applications

NASA Technical Reports Server (NTRS)

Jeram, Geoffrey J.

2004-01-01

This Open Platform for Limit Protection guides the open design of maneuver limit protection systems in general, and manned, rotorcraft, aerospace applications in particular. The platform uses three stages of limit protection modules: limit cue creation, limit cue arbitration, and control system interface. A common set of limit cue modules provides commands that can include constraints, alerts, transfer functions, and friction. An arbitration module selects the "best" limit protection cues and distributes them to the most appropriate control path interface. This platform adopts a holistic approach to limit protection whereby it considers all potential interface points, including the pilot's visual, aural, and tactile displays; and automatic command restraint shaping for autonomous limit protection. For each functional module, this thesis guides the control system designer through the design choices and information interfaces among the modules. Limit cue module design choices include type of prediction, prediction mechanism, method of critical control calculation, and type of limit cue. Special consideration is given to the nature of the limit, particularly the level of knowledge about it, and the ramifications for limit protection design, especially with respect to intelligent control methods such as fuzzy inference systems and neural networks.

Decision Maker Perception of Information Quality: A Case Study of Military Command and Control

ERIC Educational Resources Information Center

Morgan, Grayson B.

2013-01-01

Decision maker perception of information quality cues from an "information system" (IS) and the process which creates such meta cueing, or data about cues, is a critical yet un-modeled component of "situation awareness" (SA). Examples of common information quality meta cueing for quality criteria include custom ring-tones for…

Bedside hemoglobinometry in hemodialysis patients: lessons from point-of-care testing.

PubMed

Agarwal, R; Heinz, T

2001-01-01

The HemoCue B-hemoglobin test system (HemoCue, Inc., Mission Viejo, CA) is a photometric method for rapid bedside determination of hemoglobin (Hb). We compared the performance of HemoCue measured Hb against Coulter STK-S (CSTK) measured Hb in chronic hemodialysis (HD) patients in two different settings. In the first setting, Hemocue analysis was performed by multiple HD technicians (n = 132). In the second setting, a nurse trained in proper specimen handling performed the HemoCue analysis (n = 74). Simultaneous measurement of Hb by the CSTK method was performed. First setting: Hb was 11.1+/-1.66 (SD) g/dl by CSTK and 11.7+/-2.29 g/dl by HemoCue. The HemoCue method consistently overestimated Hb by an average (SD) of 0.63 (1.267) g/dl (95% CI = 0.42 to 0.85). Hb was overestimated in 25.7% and underestimated in 2.3% of the patients by 1 g/dl or more. Thus, the HemoCue system was accurate within 1 g/dl only 72% of the time. Second setting: HemoCue overestimated Hb by an average (SD) of 0.29 (0.52) g/dl (95% CI, 0.17 to 0.41). Only 4% of all patients had errors in estimation of 1 g/dl or more. Thus, HemoCue was accurate in 96% of the patients within 1 g/dl. After reviewing the two protocols, the primary difference in the two studies was the technique used to obtain the specimens. When performed properly, Hb testing using the HemoCue testing system had a high level of agreement with CSTK. Appropriate training in specimen handling, as well as test performance, will increase accuracy and reliability of bedside hemoglobinometry.

Cannabis cue-induced brain activation correlates with drug craving in limbic and visual salience regions: Preliminary results

PubMed Central

Charboneau, Evonne J.; Dietrich, Mary S.; Park, Sohee; Cao, Aize; Watkins, Tristan J; Blackford, Jennifer U; Benningfield, Margaret M.; Martin, Peter R.; Buchowski, Maciej S.; Cowan, Ronald L.

2013-01-01

Craving is a major motivator underlying drug use and relapse but the neural correlates of cannabis craving are not well understood. This study sought to determine whether visual cannabis cues increase cannabis craving and whether cue-induced craving is associated with regional brain activation in cannabis-dependent individuals. Cannabis craving was assessed in 16 cannabis-dependent adult volunteers while they viewed cannabis cues during a functional MRI (fMRI) scan. The Marijuana Craving Questionnaire was administered immediately before and after each of three cannabis cue-exposure fMRI runs. FMRI blood-oxygenation-level-dependent (BOLD) signal intensity was determined in regions activated by cannabis cues to examine the relationship of regional brain activation to cannabis craving. Craving scores increased significantly following exposure to visual cannabis cues. Visual cues activated multiple brain regions, including inferior orbital frontal cortex, posterior cingulate gyrus, parahippocampal gyrus, hippocampus, amygdala, superior temporal pole, and occipital cortex. Craving scores at baseline and at the end of all three runs were significantly correlated with brain activation during the first fMRI run only, in the limbic system (including amygdala and hippocampus) and paralimbic system (superior temporal pole), and visual regions (occipital cortex). Cannabis cues increased craving in cannabis-dependent individuals and this increase was associated with activation in the limbic, paralimbic, and visual systems during the first fMRI run, but not subsequent fMRI runs. These results suggest that these regions may mediate visually cued aspects of drug craving. This study provides preliminary evidence for the neural basis of cue-induced cannabis craving and suggests possible neural targets for interventions targeted at treating cannabis dependence. PMID:24035535

Male but not female olfaction is crucial for intermolt mating in European lobsters (Homarus gammarus L.).

PubMed

Skog, Malin

2009-02-01

Chemical signals are common in most crustacean social interactions and are often perceived via chemosensory (olfactory) organs on the first antenna. Intermolt courtship behaviors and mating were investigated in size-matched pairs of intermolt European lobsters (Homarus gammarus) where the olfactory receptors of either the male or the female were lesioned with distilled water (olfactory ablation) or seawater (control). Matings or advanced male courtship behaviors (mounting and turning) were common in seawater controls and olfactory-ablated females. In contrast, when male olfaction was ablated with distilled water, there was not a single mating, and the only male courtship behaviors seen were a few very brief and unsuccessful mounting attempts. Individual females mated up to 5 times with different males, showing that previously inseminated females were still attractive to males. Thus, male but not female olfaction is crucial for intermolt mating in H. gammarus, indicating the presence of a female sex pheromone during the entire female molt cycle, not only at the time of molting. Female sex discrimination may be based on other cues from the male in combination with typical male behaviors.

A Portable Shoulder-Mounted Camera System for Surgical Education in Spine Surgery.

PubMed

Pham, Martin H; Ohiorhenuan, Ifije E; Patel, Neil N; Jakoi, Andre M; Hsieh, Patrick C; Acosta, Frank L; Wang, Jeffrey C; Liu, John C

2017-02-07

The past several years have demonstrated an increased recognition of operative videos as an important adjunct for resident education. Currently lacking, however, are effective methods to record video for the purposes of illustrating the techniques of minimally invasive (MIS) and complex spine surgery. We describe here our experiences developing and using a shoulder-mounted camera system for recording surgical video. Our requirements for an effective camera system included wireless portability to allow for movement around the operating room, camera mount location for comfort and loupes/headlight usage, battery life for long operative days, and sterile control of on/off recording. With this in mind, we created a shoulder-mounted camera system utilizing a GoPro™ HERO3+, its Smart Remote (GoPro, Inc., San Mateo, California), a high-capacity external battery pack, and a commercially available shoulder-mount harness. This shoulder-mounted system was more comfortable to wear for long periods of time in comparison to existing head-mounted and loupe-mounted systems. Without requiring any wired connections, the surgeon was free to move around the room as needed. Over the past several years, we have recorded numerous MIS and complex spine surgeries for the purposes of surgical video creation for resident education. Surgical videos serve as a platform to distribute important operative nuances in rich multimedia. Effective and practical camera system setups are needed to encourage the continued creation of videos to illustrate the surgical maneuvers in minimally invasive and complex spinal surgery. We describe here a novel portable shoulder-mounted camera system setup specifically designed to be worn and used for long periods of time in the operating room.

Motion cue effects on human pilot dynamics in manual control

NASA Technical Reports Server (NTRS)

Washizu, K.; Tanaka, K.; Endo, S.; Itoko, T.

1977-01-01

Two experiments were conducted to study the motion cue effects on human pilots during tracking tasks. The moving-base simulator of National Aerospace Laboratory was employed as the motion cue device, and the attitude director indicator or the projected visual field was employed as the visual cue device. The chosen controlled elements were second-order unstable systems. It was confirmed that with the aid of motion cues the pilot workload was lessened and consequently the human controllability limits were enlarged. In order to clarify the mechanism of these effects, the describing functions of the human pilots were identified by making use of the spectral and the time domain analyses. The results of these analyses suggest that the sensory system of the motion cues can yield the differential informations of the signal effectively, which coincides with the existing knowledges in the physiological area.

External cues challenging the internal appetite control system-Overview and practical implications.

PubMed

Bilman, Els; van Kleef, Ellen; van Trijp, Hans

2017-09-02

Inadequate regulation of food intake plays an important role in the development of overweight and obesity, and is under the influence of both the internal appetite control system and external environmental cues. Especially in environments where food is overly available, external cues seem to override and/or undermine internal signals, which put severe challenges on the accurate regulation of food intake. By structuring these external cues around five different phases in the food consumption process this paper aims to provide an overview of the wide range of external cues that potentially facilitate or hamper internal signals and with that influence food intake. For each of the five phases of the food consumption process, meal initiation, meal planning, consumption phase, end of eating episode and time till next meal, the most relevant internal signals are discussed and it is explained how specific external cues exert their influence.

Role of Dopamine 2 Receptor in Impaired Drug-Cue Extinction in Adolescent Rats.

PubMed

Zbukvic, Isabel C; Ganella, Despina E; Perry, Christina J; Madsen, Heather B; Bye, Christopher R; Lawrence, Andrew J; Kim, Jee Hyun

2016-06-01

Adolescent drug users display resistance to treatment such as cue exposure therapy (CET), as well as increased liability to relapse. The basis of CET is extinction learning, which involves dopamine signaling in the medial prefrontal cortex (mPFC). This system undergoes dramatic alterations during adolescence. Therefore, we investigated extinction of a cocaine-associated cue in adolescent and adult rats. While cocaine self-administration and lever-alone extinction were not different between the two ages, we observed that cue extinction reduced cue-induced reinstatement in adult but not adolescent rats. Infusion of the selective dopamine 2 receptor (D2R)-like agonist quinpirole into the infralimbic cortex (IL) of the mPFC prior to cue extinction significantly reduced cue-induced reinstatement in adolescents. This effect was replicated by acute systemic treatment with the atypical antipsychotic aripiprazole (Abilify), a partial D2R-like agonist. These data suggest that adolescents may be more susceptible to relapse due to a deficit in cue extinction learning, and highlight the significance of D2R signaling in the IL for cue extinction during adolescence. These findings inspire new tactics for improving adolescent CET, with aripiprazole representing an exciting potential pharmacological adjunct for behavioral therapy. © The Author 2016. Published by Oxford University Press.

Effects of Presentation Type and Visual Control in Numerosity Discrimination: Implications for Number Processing?

PubMed Central

Smets, Karolien; Moors, Pieter; Reynvoet, Bert

2016-01-01

Performance in a non-symbolic comparison task in which participants are asked to indicate the larger numerosity of two dot arrays, is assumed to be supported by the Approximate Number System (ANS). This system allows participants to judge numerosity independently from other visual cues. Supporting this idea, previous studies indicated that numerosity can be processed when visual cues are controlled for. Consequently, distinct types of visual cue control are assumed to be interchangeable. However, a previous study showed that the type of visual cue control affected performance using a simultaneous presentation of the stimuli in numerosity comparison. In the current study, we explored whether the influence of the type of visual cue control on performance disappeared when sequentially presenting each stimulus in numerosity comparison. While the influence of the applied type of visual cue control was significantly more evident in the simultaneous condition, sequentially presenting the stimuli did not completely exclude the influence of distinct types of visual cue control. Altogether, these results indicate that the implicit assumption that it is possible to compare performances across studies with a differential visual cue control is unwarranted and that the influence of the type of visual cue control partly depends on the presentation format of the stimuli. PMID:26869967

Improving visual spatial working memory in younger and older adults: effects of cross-modal cues.

PubMed

Curtis, Ashley F; Turner, Gary R; Park, Norman W; Murtha, Susan J E

2017-11-06

Spatially informative auditory and vibrotactile (cross-modal) cues can facilitate attention but little is known about how similar cues influence visual spatial working memory (WM) across the adult lifespan. We investigated the effects of cues (spatially informative or alerting pre-cues vs. no cues), cue modality (auditory vs. vibrotactile vs. visual), memory array size (four vs. six items), and maintenance delay (900 vs. 1800 ms) on visual spatial location WM recognition accuracy in younger adults (YA) and older adults (OA). We observed a significant interaction between spatially informative pre-cue type, array size, and delay. OA and YA benefitted equally from spatially informative pre-cues, suggesting that attentional orienting prior to WM encoding, regardless of cue modality, is preserved with age.  Contrary to predictions, alerting pre-cues generally impaired performance in both age groups, suggesting that maintaining a vigilant state of arousal by facilitating the alerting attention system does not help visual spatial location WM.

Three-dimensional repositioning accuracy of semiadjustable articulator cast mounting systems.

PubMed

Tan, Ming Yi; Ung, Justina Youlin; Low, Ada Hui Yin; Tan, En En; Tan, Keson Beng Choon

2014-10-01

In spite of its importance in prosthesis precision and quality, the 3-dimensional repositioning accuracy of cast mounting systems has not been reported in detail. The purpose of this study was to quantify the 3-dimensional repositioning accuracy of 6 selected cast mounting systems. Five magnetic mounting systems were compared with a conventional screw-on system. Six systems on 3 semiadjustable articulators were evaluated: Denar Mark II with conventional screw-on mounting plates (DENSCR) and magnetic mounting system with converter plates (DENCON); Denar Mark 330 with in-built magnetic mounting system (DENMAG) and disposable mounting plates; and Artex CP with blue (ARTBLU), white (ARTWHI), and black (ARTBLA) magnetic mounting plates. Test casts with 3 high-precision ceramic ball bearings at the mandibular central incisor (Point I) and the right and left second molar (Point R; Point L) positions were mounted on 5 mounting plates (n=5) for all 6 systems. Each cast was repositioned 10 times by 4 operators in random order. Nine linear (Ix, Iy, Iz; Rx, Ry, Rz; Lx, Ly, Lz) and 3 angular (anteroposterior, mediolateral, twisting) displacements were measured with a coordinate measuring machine. The mean standard deviations of the linear and angular displacements defined repositioning accuracy. Anteroposterior linear repositioning accuracy ranged from 23.8 ±3.7 μm (DENCON) to 4.9 ±3.2 μm (DENSCR). Mediolateral linear repositioning accuracy ranged from 46.0 ±8.0 μm (DENCON) to 3.7 ±1.5 μm (ARTBLU), and vertical linear repositioning accuracy ranged from 7.2 ±9.6 μm (DENMAG) to 1.5 ±0.9 μm (ARTBLU). Anteroposterior angular repositioning accuracy ranged from 0.0084 ±0.0080 degrees (DENCON) to 0.0020 ±0.0006 degrees (ARTBLU), and mediolateral angular repositioning accuracy ranged from 0.0120 ±0.0111 degrees (ARTWHI) to 0.0027 ±0.0008 degrees (ARTBLU). Twisting angular repositioning accuracy ranged from 0.0419 ±0.0176 degrees (DENCON) to 0.0042 ±0.0038 degrees (ARTBLA). One-way ANOVA found significant differences (P<.05) among all systems for Iy, Ry, Lx, Ly, and twisting. Generally, vertical linear displacements were less likely to reach the threshold of clinical detectability compared with anteroposterior or mediolateral linear displacements. The overall repositioning accuracy of DENSCR was comparable with 4 magnetic mounting systems (DENMAG, ARTBLU, ARTWHI, ARTBLA). DENCON exhibited the worst repositioning accuracy for Iy, Ry, Lx, Ly, and twisting. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Evaluating the effects of delivering integrated kinesthetic and tactile cues to individuals with unilateral hemiparetic stroke during overground walking.

PubMed

Afzal, Muhammad Raheel; Pyo, Sanghun; Oh, Min-Kyun; Park, Young Sook; Yoon, Jungwon

2018-04-16

Integration of kinesthetic and tactile cues for application to post-stroke gait rehabilitation is a novel concept which needs to be explored. The combined provision of haptic cues may result in collective improvement of gait parameters such as symmetry, balance and muscle activation patterns. Our proposed integrated cue system can offer a cost-effective and voluntary gait training experience for rehabilitation of subjects with unilateral hemiparetic stroke. Ten post-stroke ambulatory subjects participated in a 10 m walking trial while utilizing the haptic cues (either alone or integrated application), at their preferred and increased gait speeds. In the system a haptic cane device (HCD) provided kinesthetic perception and a vibrotactile feedback device (VFD) provided tactile cue on the paretic leg for gait modification. Balance, gait symmetry and muscle activity were analyzed to identify the benefits of utilizing the proposed system. When using kinesthetic cues, either alone or integrated with a tactile cue, an increase in the percentage of non-paretic peak activity in the paretic muscles was observed at the preferred gait speed (vastus medialis obliquus: p <  0.001, partial eta squared (η 2 ) = 0.954; semitendinosus p <  0.001, partial η 2  = 0.793) and increased gait speeds (vastus medialis obliquus: p <  0.001, partial η 2  = 0.881; semitendinosus p = 0.028, partial η 2  = 0.399). While using HCD and VFD (individual and integrated applications), subjects could walk at their preferred and increased gait speeds without disrupting trunk balance in the mediolateral direction. The temporal stance symmetry ratio was improved when using tactile cues, either alone or integrated with a kinesthetic cue, at their preferred gait speed (p <  0.001, partial η 2  = 0.702). When combining haptic cues, the subjects walked at their preferred gait speed with increased temporal stance symmetry and paretic muscle activity affecting their balance. Similar improvements were observed at higher gait speeds. The efficacy of the proposed system is influenced by gait speed. Improvements were observed at a 20% increased gait speed, whereas, a plateau effect was observed at a 40% increased gait speed. These results imply that integration of haptic cues may benefit post-stroke gait rehabilitation by inducing simultaneous improvements in gait symmetry and muscle activity.

Naloxone injections into CA3 disrupt pattern completion associated with relapse from cocaine seeking.

PubMed

Kesner, Raymond P; Kirk, Ryan A; Clark, Jascha K; Moore, Angela; Keefe, Kristen

2016-07-01

The goal of the present research was to assess the degree to which a pattern completion process operates in cue-induced relapse to cocaine-seeking behavior. Using a novel cue-preference version of the place preference task, rats were administered cocaine or saline, which resulted in a preference for the cocaine-paired cues. After 21 days of abstinence and prior to the preference test, for one group, PBS or naloxone was injected into the CA3 subregion of the hippocampus and for a second group, saline or naloxone was injected systemically. The results indicated that infusions of naloxone into CA3 or systemic injections produced a marked disruption for one and two cues, but had minimal disruptive effect for three or four cues, suggesting that naloxone injections disrupt CA3 function and trigger a deficit in a pattern completion process. Thus, it appears that cue-based activation of the dorsal CA3 might be a critical trigger via a pattern completion process. Based on additional analyses it appears that there is a disruption primarily for object touches for one cue naloxone injections into the CA3 or systemic injections, but no effect on time (spatial context). © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Spiny lobsters detect conspecific blood-borne alarm cues exclusively through olfactory sensilla.

PubMed

Shabani, Shkelzen; Kamio, Michiya; Derby, Charles D

2008-08-01

When attacked by predators, diverse animals actively or passively release molecules that evoke alarm and related anti-predatory behavior by nearby conspecifics. The actively released molecules are alarm pheromones, whereas the passively released molecules are alarm cues. For example, many insects have alarm-signaling systems that involve active release of alarm pheromones from specialized glands and detection of these signals using specific sensors. Many crustaceans passively release alarm cues, but the nature of the cues, sensors and responses is poorly characterized. Here we show in laboratory and field experiments that injured Caribbean spiny lobsters, Panulirus argus, passively release alarm cues via blood (hemolymph) that induce alarm responses in the form of avoidance and suppression of feeding. These cues are detected exclusively through specific olfactory chemosensors, the aesthetasc sensilla. The alarm cues for Caribbean spiny lobsters are not unique to the species but do show some phylogenetic specificity: P. argus responds primarily with alarm behavior to conspecific blood, but with mixed alarm and appetitive behaviors to blood from the congener Panulirus interruptus, or with appetitive behaviors to blood from the blue crab Callinectes sapidus. This study lays the foundation for future neuroethological studies of alarm cue systems in this and other decapod crustaceans.

Nucleus Accumbens Acetylcholine Receptors Modulate Dopamine and Motivation.

PubMed

Collins, Anne L; Aitken, Tara J; Greenfield, Venuz Y; Ostlund, Sean B; Wassum, Kate M

2016-11-01

Environmental reward-predictive cues can motivate reward-seeking behaviors. Although this influence is normally adaptive, it can become maladaptive in disordered states, such as addiction. Dopamine release in the nucleus accumbens core (NAc) is known to mediate the motivational impact of reward-predictive cues, but little is known about how other neuromodulatory systems contribute to cue-motivated behavior. Here, we examined the role of the NAc cholinergic receptor system in cue-motivated behavior using a Pavlovian-to-instrumental transfer task designed to assess the motivating influence of a reward-predictive cue over an independently-trained instrumental action. Disruption of NAc muscarinic acetylcholine receptor activity attenuated, whereas blockade of nicotinic receptors augmented cue-induced invigoration of reward seeking. We next examined a potential dopaminergic mechanism for this behavioral effect by combining fast-scan cyclic voltammetry with local pharmacological acetylcholine receptor manipulation. The data show evidence of opposing modulation of cue-evoked dopamine release, with muscarinic and nicotinic receptor antagonists causing suppression and augmentation, respectively, consistent with the behavioral effects of these manipulations. In addition to demonstrating cholinergic modulation of naturally-evoked and behaviorally-relevant dopamine signaling, these data suggest that NAc cholinergic receptors may gate the expression of cue-motivated behavior through modulation of phasic dopamine release.

The Effects of Various Mounting Systems of near Magnification on Reading Performance and Preference in School-Age Students with Low Vision

ERIC Educational Resources Information Center

Lusk, Kelly E.

2012-01-01

This single-subject study explored the effects of different mounting systems of prescribed near magnification (handheld, stand-mounted, spectacle-mounted, and electronic) on reading performance and preference in students with low vision. Participants included five students ranging from 3rd to 11th grade, and with various etiologies. Reading…

Project CUES: A New Middle-School Earth System Science Curriculum Being Developed by the American Geological Institute

NASA Astrophysics Data System (ADS)

Smith, M. C.; Smith, M. J.; Lederman, N.; Southard, J. B.; Rogers, E. A.; Callahan, C. N.

2002-12-01

Project CUES is a middle-school earth systems science curriculum project under development by the American Geological Institute (AGI) and funded by the National Science Foundation (ESI-0095938). CUES features a student-centered, inquiry pedagogy and approaches earth science from a systems perspective. CUES will use the expanded learning cycle approach of Trowbridge and Bybee (1996), known as the 5E model (engage-explore-explain-elaborate-evaluate). Unlike AGI's Investigating Earth Systems (IES) curriculum modules, CUES will include a single hard-bound textbook, and will take one school-year to complete. The textbook includes a prologue that addresses systems concepts and four main units: Geosphere, Hydrosphere, Atmosphere, and Biosphere. Each eight-week unit takes students through a progression from guided inquiry to open-ended, student-driven inquiry. During first 4 to 5 weeks of each unit, students explore important earth science phenomena and concepts through scripted investigations and narrative reading passages written by scientists as "inquiry narratives". The narratives address the development of scientific ideas and relay the personal experiences of a scientist during their scientific exploration. Aspects of the nature of science will be explicitly addressed in investigations and inquiry narratives. After the guided inquiry, students will develop a research proposal and conduct their own inquiry into local or regional scientific problems. Each unit culminates with a science conference at which students present their research. CUES will be the first NSF-funded, comprehensive earth systems textbook for middle school that is based on national standards. CUES will be pilot tested in 12 classrooms in January 2003, with a national field test of the program in 50 classrooms during the 2003-2004 school year.

A method for estimating mount isolations of powertrain mounting systems

NASA Astrophysics Data System (ADS)

Qin, Wu; Shangguan, Wen-Bin; Luo, Guohai; Xie, Zhengchao

2018-07-01

A method for calculating isolation ratios of mounts at a powertrain mounting systems (PMS) is proposed assuming a powertrain as a rigid body and using the identified powertrain excitation forces and the measured IPI (input point inertance) of mounting points at the body side. With measured accelerations of mounts at powertrain and body sides of one Vehicle (Vehicle A), the excitation forces of a powertrain are identified using conversational method firstly. Another Vehicle (Vehicle B) has the same powertrain as that of Vehicle A, but with different body and mount configuration. The accelerations of mounts at powertrain side of a PMS on Vehicle B are calculated using the powertrain excitation forces identified from Vehicle A. The identified forces of the powertrain are validated by comparing the calculated and the measured accelerations of mounts at the powertrain side of the powertrain on Vehicle B. A method for calculating acceleration of mounting point at body side for Vehicle B is presented using the identified powertrain excitation forces and the measured IPI at a connecting point between car body and mount. Using the calculated accelerations of mounts at powertrain side and body side at different directions, the isolation ratios of a mount are then estimated. The isolation ratios are validated using the experiment, which verified the proposed methods for estimating isolation ratios of mounts. The developed method is beneficial for optimizing mount stiffness to meet mount isolation requirements before prototype.

Vibration control of a ship engine system using high-load magnetorheological mounts associated with a new indirect fuzzy sliding mode controller

NASA Astrophysics Data System (ADS)

Phu, Do Xuan; Choi, Seung-Bok

2015-02-01

In this work, a new high-load magnetorheological (MR) fluid mount system is devised and applied to control vibration in a ship engine. In the investigation of vibration-control performance, a new modified indirect fuzzy sliding mode controller is formulated and realized. The design of the proposed MR mount is based on the flow mode of MR fluid, and it includes two separated coils for generating a magnetic field. An optimization process is carried out to achieve maximal damping force under certain design constraints, such as the allowable height of the mount. As an actuating smart fluid, a new plate-like iron-particle-based MR fluid is used, instead of the conventional spherical iron-particle-based MR fluid. After evaluating the field-dependent yield stress of the MR fluid, the field-dependent damping force required to control unwanted vibration in the ship engine is determined. Subsequently, an appropriate-sized MR mount is manufactured and its damping characteristics are evaluated. After confirming the sufficient damping force level of the manufactured MR mount, a medium-sized ship engine mount system consisting of eight MR mounts is established, and its dynamic governing equations are derived. A new modified indirect fuzzy sliding mode controller is then formulated and applied to the engine mount system. The displacement and velocity responses show that the unwanted vibrations of the ship engine system can be effectively controlled in both the axial and radial directions by applying the proposed control methodology.

Helicopter flight simulation motion platform requirements

NASA Astrophysics Data System (ADS)

Schroeder, Jeffery Allyn

Flight simulators attempt to reproduce in-flight pilot-vehicle behavior on the ground. This reproduction is challenging for helicopter simulators, as the pilot is often inextricably dependent on external cues for pilot-vehicle stabilization. One important simulator cue is platform motion; however, its required fidelity is unknown. To determine the required motion fidelity, several unique experiments were performed. A large displacement motion platform was used that allowed pilots to fly tasks with matched motion and visual cues. Then, the platform motion was modified to give cues varying from full motion to no motion. Several key results were found. First, lateral and vertical translational platform cues had significant effects on fidelity. Their presence improved performance and reduced pilot workload. Second, yaw and roll rotational platform cues were not as important as the translational platform cues. In particular, the yaw rotational motion platform cue did not appear at all useful in improving performance or reducing workload. Third, when the lateral translational platform cue was combined with visual yaw rotational cues, pilots believed the platform was rotating when it was not. Thus, simulator systems can be made more efficient by proper combination of platform and visual cues. Fourth, motion fidelity specifications were revised that now provide simulator users with a better prediction of motion fidelity based upon the frequency responses of their motion control laws. Fifth, vertical platform motion affected pilot estimates of steady-state altitude during altitude repositionings. This refutes the view that pilots estimate altitude and altitude rate in simulation solely from visual cues. Finally, the combined results led to a general method for configuring helicopter motion systems and for developing simulator tasks that more likely represent actual flight. The overall results can serve as a guide to future simulator designers and to today's operators.

Inclusion of Specialist and Generalist Stimuli in Attract-and-Kill Programs: Their Relative Efficacy in Apple Maggot Fly (Diptera: Tephritidae) Pest Management.

PubMed

Morrison, William R; Lee, Doo-Hyung; Reissig, W Harvey; Combs, David; Leahy, Kathleen; Tuttle, Arthur; Cooley, Daniel; Leskey, Tracy C

2016-08-01

Investigating the chemical ecology of agricultural systems continues to be a salient part of integrated pest management programs. Apple maggot fly, a key pest of apple in eastern North America, is a visual specialist with attraction to host fruit-mimicking cues. These cues have been incorporated into red spherical traps used for both monitoring and behaviorally based management. Incorporating generalist or specialist olfactory cues can potentially increase the overall success of this management system. The primary aim of this study was to evaluate the attractiveness of a generalist olfactory cue, ammonium carbonate, and the specialist olfactory cue, a five-component apple volatile blend, when included as a component of a red attracticidal sphere system. Secondly, we assessed how critical it was to maintain minimal deviation from the optimal, full-round specialist visual stimulus provided by red spheres. Finally, attracticidal spheres were deployed with specialist olfactory cues in commercial apple orchards to evaluate their potential for effective management of apple maggot. Ammonium carbonate did not increase residency, feeding time, or mortality in the laboratory-based trials. Field deployment of specialist olfactory cues increased apple maggot captures on red spheres, while the generalist cue did not. Apple maggot tolerated some deviation from the optimal visual stimulus without reducing captures on red spheres. Attracticidal spheres hung in perimeter trees in orchards resulted in acceptable and statistically identical levels of control compared with standard insecticide programs used by growers. Overall, our study contributes valuable information for developing a reliable attract-and-kill system for apple maggot. Published by Oxford University Press on behalf of Entomological Society of America 2016. This work is written by US Government employees and is in the public domain in the United States.

Development of CO2 laser Doppler instrumentation for detection of clear air turbulence, volume 2: Appendices

NASA Technical Reports Server (NTRS)

Harris, C. E.; Jelalian, A. V.

1979-01-01

Analyses of the mounting and mount support systems of the clear air turbulence transmitters verify that satisfactory shock and vibration isolation are attained. The mount support structure conforms to flight crash safety requirements with high margins of safety. Restraint cables reinforce the mounts in the critical loaded forward direction limiting maximum forward system deflection to 1 1/4 inches.

Chaoborus and gasterosteus anti-predator responses in Daphnia pulex are mediated by independent cholinergic and gabaergic neuronal signals.

PubMed

Weiss, Linda C; Kruppert, Sebastian; Laforsch, Christian; Tollrian, Ralph

2012-01-01

Many prey species evolved inducible defense strategies that protect effectively against predation threats. Especially the crustacean Daphnia emerged as a model system for studying the ecology and evolution of inducible defenses. Daphnia pulex e.g. shows different phenotypic adaptations against vertebrate and invertebrate predators. In response to the invertebrate phantom midge larvae Chaoborus (Diptera) D. pulex develops defensive morphological defenses (neckteeth). Cues originating from predatory fish result in life history changes in which resources are allocated from somatic growth to reproduction. While there are hints that responses against Chaoborus cues are transmitted involving cholinergic neuronal pathways, nothing is known about the neurophysiology underlying the transmission of fish related cues. We investigated the neurophysiological basis underlying the activation of inducible defenses in D. pulex using induction assays with the invertebrate predator Chaoborus and the three-spined stickleback Gasterosteus aculeatus. Predator-specific cues were combined with neuro-effective substances that stimulated or inhibited the cholinergic and gabaergic nervous system. We show that cholinergic-dependent pathways are involved in the perception and transmission of Chaoborus cues, while GABA was not involved. Thus, the cholinergic nervous system independently mediates the development of morphological defenses in response to Chaoborus cues. In contrast, only the inhibitory effect of GABA significantly influence fish-induced life history changes, while the application of cholinergic stimulants had no effect in combination with fish related cues. Our results show that cholinergic stimulation mediates signal transmission of Chaoborus cues leading to morphological defenses. Fish cues, which are responsible for predator-specific life history adaptations involve gabaergic control. Our study shows that both pathways are independent and thus potentially allow for adjustment of responses to variable predation regimes.

Prolonged Walking with a Wearable System Providing Intelligent Auditory Input in People with Parkinson's Disease.

PubMed

Ginis, Pieter; Heremans, Elke; Ferrari, Alberto; Dockx, Kim; Canning, Colleen G; Nieuwboer, Alice

2017-01-01

Rhythmic auditory cueing is a well-accepted tool for gait rehabilitation in Parkinson's disease (PD), which can now be applied in a performance-adapted fashion due to technological advance. This study investigated the immediate differences on gait during a prolonged, 30 min, walk with performance-adapted (intelligent) auditory cueing and verbal feedback provided by a wearable sensor-based system as alternatives for traditional cueing. Additionally, potential effects on self-perceived fatigue were assessed. Twenty-eight people with PD and 13 age-matched healthy elderly (HE) performed four 30 min walks with a wearable cue and feedback system. In randomized order, participants received: (1) continuous auditory cueing; (2) intelligent cueing (10 metronome beats triggered by a deviating walking rhythm); (3) intelligent feedback (verbal instructions triggered by a deviating walking rhythm); and (4) no external input. Fatigue was self-scored at rest and after walking during each session. The results showed that while HE were able to maintain cadence for 30 min during all conditions, cadence in PD significantly declined without input. With continuous cueing and intelligent feedback people with PD were able to maintain cadence ( p  = 0.04), although they were more physically fatigued than HE. Furthermore, cadence deviated significantly more in people with PD than in HE without input and particularly with intelligent feedback (both: p  = 0.04). In PD, continuous and intelligent cueing induced significantly less deviations of cadence ( p  = 0.006). Altogether, this suggests that intelligent cueing is a suitable alternative for the continuous mode during prolonged walking in PD, as it induced similar effects on gait without generating levels of fatigue beyond that of HE.

Prospective memory failures in aviation: effects of cue salience, workload, and individual differences.

PubMed

Van Benthem, Kathleen D; Herdman, Chris M; Tolton, Rani G; LeFevre, Jo-Anne

2015-04-01

Prospective memory allows people to complete intended tasks in the future. Prospective memory failures, such as pilots forgetting to inform pattern traffic of their locations, can have fatal consequences. The present research examined the impact of system factors (memory cue salience and workload) and individual differences (pilot age, cognitive health, and expertise) on prospective memory for communication tasks in the cockpit. Pilots (N = 101) flew a Cessna 172 simulator at a non-towered aerodrome while maintaining communication with traffic and attending to flight parameters. Memory cue salience (the prominence of cues that signal an intended action) and workload were manipulated. Prospective memory was measured as radio call completion rates. Pilots' prospective memory was adversely affected by low-salience cues and high workload. An interaction of cue salience, pilots' age, and cognitive health reflected the effects of system and individual difference factors on prospective memory failures. For example, younger pilots with low levels of cognitive health completed 78% of the radio calls associated with low-salience memory cues, whereas older pilots with low cognitive health scores completed just 61% of similar radio calls. Our findings suggest that technologies designed to signal intended future tasks should target those tasks with inherently low-salience memory cues. In addition, increasing the salience of memory cues is most likely to benefit pilots with lower levels of cognitive health in high-workload conditions.

Depth Perception and Defensive System Activation in a 3-D Environment

PubMed Central

Combe, Emmanuelle; Fujii, Naotaka

2011-01-01

To survive, animals must be able to react appropriately (in temporal and behavioral terms) when facing a threat. One of the essential parameters considered by the defensive system is the distance of the threat, the “defensive distance.” In this study, we investigate the visual depth cues that could be considered as an alarm cue for the activation of the defensive system. For this purpose, we performed an active-escape pain task in a virtual three-dimensional environment. In two experiments, we manipulated the nature and consistency of different depth cues: vergence, linear perspective, and angular size. By measuring skin conductance responses, we characterized the situations that activated the defensive system. We show that the angular size of the predator was sufficient information to trigger responses from the defensive system, but we also demonstrate that vergence, which can delay the emotional response in inconsistent situations, is also a highly reliable cue for the activation of the defensive system. PMID:21941515

Visual/motion cue mismatch in a coordinated roll maneuver

NASA Technical Reports Server (NTRS)

Shirachi, D. K.; Shirley, R. S.

1981-01-01

The effects of bandwidth differences between visual and motion cueing systems on pilot performance for a coordinated roll task were investigated. Visual and motion cue configurations which were acceptable and the effects of reduced motion cue scaling on pilot performance were studied to determine the scale reduction threshold for which pilot performance was significantly different from full scale pilot performance. It is concluded that: (1) the presence or absence of high frequency error information in the visual and/or motion display systems significantly affects pilot performance; and (2) the attenuation of motion scaling while maintaining other display dynamic characteristics constant, affects pilot performance.

The effectiveness of sentence cues in measuring the Big Three motives.

PubMed

Langan-Fox, Janice; Grant, Sharon

2007-10-01

Despite the popularity of free response measures in the motivation literature, research geared toward the development of a standard battery of cues for measuring the Big Three motives (achievement, affiliation, power) has been lacking. The current research examined the effectiveness of sentence cues in eliciting motive imagery in two studies (students, entrepreneurs) comprising 242 men and women. Results indicated that sentence cues were effective in eliciting achievement and affiliation imagery, but not power imagery. In addition, an examination of the subcategories underlying each motive scoring system indicated that there were several infrequently scored subcategories in the achievement and power motive scoring systems that could be considered for removal.

76 FR 4097 - Verdant Power, LLC (Verdant); Notice of Application Tendered for Filing With the Commission and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

... facilities would include: (1) Three 35-kilowatt (kW), 5-meter-diameter axial flow Kinetic System turbine...; (2) nine additional 5-meter-diameter axial flow Kinetic System turbine generator units mounted on...-meter-diameter axial flow Kinetic System turbine generator units mounted on six triframe mounts, with a...

Reactivity to Cannabis Cues in Virtual Reality Environments†

PubMed Central

Bordnick, Patrick S.; Copp, Hilary L.; Traylor, Amy; Graap, Ken M.; Carter, Brian L.; Walton, Alicia; Ferrer, Mirtha

2014-01-01

Virtual reality (VR) cue environments have been developed and successfully tested in nicotine, cocaine, and alcohol abusers. Aims in the current article include the development and testing of a novel VR cannabis cue reactivity assessment system. It was hypothesized that subjective craving levels and attention to cannabis cues would be higher in VR environments merits with cannabis cues compared to VR neutral environments. Twenty nontreatment-seeking current cannabis smokers participated in the VR cue trial. During the VR cue trial, participants were exposed to four virtual environments that contained audio, visual, olfactory, and vibrotactile sensory stimuli. Two VR environments contained cannabis cues that consisted of a party room in which people were smoking cannabis and a room containing cannabis paraphernalia without people. Two VR neutral rooms without cannabis cues consisted of a digital art gallery with nature videos. Subjective craving and attention to cues were significantly higher in the VR cannabis environments compared to the VR neutral environments. These findings indicate that VR cannabis cue reactivity may offer a new technology-based method to advance addiction research and treatment. PMID:19705672

Second Generation Electronic Nicotine Delivery System Vape Pen Exposure Generalizes as a Smoking Cue.

PubMed

King, Andrea C; Smith, Lia J; McNamara, Patrick J; Cao, Dingcai

2018-01-05

Second generation electronic nicotine delivery systems (ENDS; also known as e-cigarettes, vaporizers or vape pens) are designed for a customized nicotine delivery experience and have less resemblance to regular cigarettes than first generation "cigalikes." The present study examined whether they generalize as a conditioned cue and evoke smoking urges or behavior in persons exposed to their use. Data were analyzed in N = 108 young adult smokers (≥5 cigarettes per week) randomized to either a traditional combustible cigarette smoking cue or a second generation ENDS vaping cue in a controlled laboratory setting. Cigarette and e-cigarette urge and desire were assessed pre- and post-cue exposure. Smoking behavior was also explored in a subsample undergoing a smoking latency phase after cue exposure (N = 26). The ENDS vape pen cue evoked both urge and desire for a regular cigarette to a similar extent as that produced by the combustible cigarette cue. Both cues produced similar time to initiate smoking during the smoking latency phase. The ENDS vape pen cue elicited smoking urge and desire regardless of ENDS use history, that is, across ENDS naїve, lifetime or current users. Inclusion of past ENDS or cigarette use as covariates did not significantly alter the results. These findings demonstrate that observation of vape pen ENDS use generalizes as a conditioned cue to produce smoking urge, desire, and behavior in young adult smokers. As the popularity of these devices may eventually overtake those of first generation ENDS cigalikes, exposure effects will be of increasing importance. This study shows that passive exposure to a second generation ENDS vape pen cue evoked smoking urge, desire, and behavior across a range of daily and non-daily young adult smokers. Smoking urge and desire increases after vape pen exposure were similar to those produced by exposure to a first generation ENDS cigalike and a combustible cigarette, a known potent cue. Given the increasing popularity of ENDS tank system products, passive exposures to these devices will no doubt increase, and may contribute to tobacco use in young adult smokers. © The Author(s) 2017. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Neural Mechanism for Mirrored Self-face Recognition.

PubMed

Sugiura, Motoaki; Miyauchi, Carlos Makoto; Kotozaki, Yuka; Akimoto, Yoritaka; Nozawa, Takayuki; Yomogida, Yukihito; Hanawa, Sugiko; Yamamoto, Yuki; Sakuma, Atsushi; Nakagawa, Seishu; Kawashima, Ryuta

2015-09-01

Self-face recognition in the mirror is considered to involve multiple processes that integrate 2 perceptual cues: temporal contingency of the visual feedback on one's action (contingency cue) and matching with self-face representation in long-term memory (figurative cue). The aim of this study was to examine the neural bases of these processes by manipulating 2 perceptual cues using a "virtual mirror" system. This system allowed online dynamic presentations of real-time and delayed self- or other facial actions. Perception-level processes were identified as responses to only a single perceptual cue. The effect of the contingency cue was identified in the cuneus. The regions sensitive to the figurative cue were subdivided by the response to a static self-face, which was identified in the right temporal, parietal, and frontal regions, but not in the bilateral occipitoparietal regions. Semantic- or integration-level processes, including amodal self-representation and belief validation, which allow modality-independent self-recognition and the resolution of potential conflicts between perceptual cues, respectively, were identified in distinct regions in the right frontal and insular cortices. The results are supportive of the multicomponent notion of self-recognition and suggest a critical role for contingency detection in the co-emergence of self-recognition and empathy in infants. © The Author 2014. Published by Oxford University Press.

Neural Mechanism for Mirrored Self-face Recognition

PubMed Central

Sugiura, Motoaki; Miyauchi, Carlos Makoto; Kotozaki, Yuka; Akimoto, Yoritaka; Nozawa, Takayuki; Yomogida, Yukihito; Hanawa, Sugiko; Yamamoto, Yuki; Sakuma, Atsushi; Nakagawa, Seishu; Kawashima, Ryuta

2015-01-01

Self-face recognition in the mirror is considered to involve multiple processes that integrate 2 perceptual cues: temporal contingency of the visual feedback on one's action (contingency cue) and matching with self-face representation in long-term memory (figurative cue). The aim of this study was to examine the neural bases of these processes by manipulating 2 perceptual cues using a “virtual mirror” system. This system allowed online dynamic presentations of real-time and delayed self- or other facial actions. Perception-level processes were identified as responses to only a single perceptual cue. The effect of the contingency cue was identified in the cuneus. The regions sensitive to the figurative cue were subdivided by the response to a static self-face, which was identified in the right temporal, parietal, and frontal regions, but not in the bilateral occipitoparietal regions. Semantic- or integration-level processes, including amodal self-representation and belief validation, which allow modality-independent self-recognition and the resolution of potential conflicts between perceptual cues, respectively, were identified in distinct regions in the right frontal and insular cortices. The results are supportive of the multicomponent notion of self-recognition and suggest a critical role for contingency detection in the co-emergence of self-recognition and empathy in infants. PMID:24770712

GPS compound eye attitude and navigation sensor and method

NASA Technical Reports Server (NTRS)

Quinn, David A. (Inventor)

2003-01-01

The present invention is a GPS system for navigation and attitude determination, comprising a sensor array including a convex hemispherical mounting structure having a plurality of mounting surfaces, and a plurality of antennas mounted to the mounting surfaces for receiving signals from space vehicles of a GPS constellation. The present invention also includes a receiver for collecting the signals and making navigation and attitude determinations. In an alternate embodiment the present invention may include two opposing convex hemispherical mounting structures, each of the mounting structures having a plurality of mounting surfaces, and a plurality of antennas mounted to the mounting surfaces.

Meninges-derived cues control axon guidance.

PubMed

Suter, Tracey A C S; DeLoughery, Zachary J; Jaworski, Alexander

2017-10-01

The axons of developing neurons travel long distances along stereotyped pathways under the direction of extracellular cues sensed by the axonal growth cone. Guidance cues are either secreted proteins that diffuse freely or bind the extracellular matrix, or membrane-anchored proteins. Different populations of axons express distinct sets of receptors for guidance cues, which results in differential responses to specific ligands. The full repertoire of axon guidance cues and receptors and the identity of the tissues producing these cues remain to be elucidated. The meninges are connective tissue layers enveloping the vertebrate brain and spinal cord that serve to protect the central nervous system (CNS). The meninges also instruct nervous system development by regulating the generation and migration of neural progenitors, but it has not been determined whether they help guide axons to their targets. Here, we investigate a possible role for the meninges in neuronal wiring. Using mouse neural tissue explants, we show that developing spinal cord meninges produce secreted attractive and repulsive cues that can guide multiple types of axons in vitro. We find that motor and sensory neurons, which project axons across the CNS-peripheral nervous system (PNS) boundary, are attracted by meninges. Conversely, axons of both ipsi- and contralaterally projecting dorsal spinal cord interneurons are repelled by meninges. The responses of these axonal populations to the meninges are consistent with their trajectories relative to meninges in vivo, suggesting that meningeal guidance factors contribute to nervous system wiring and control which axons are able to traverse the CNS-PNS boundary. Copyright © 2017 Elsevier Inc. All rights reserved.

Sexual behavior and sex-associated environmental cues activate the mesolimbic system in male rats.

PubMed

Balfour, Margaret E; Yu, Lei; Coolen, Lique M

2004-04-01

The mesolimbic system plays an important role in the regulation of both pathological behaviors such as drug addiction and normal motivated behaviors such as sexual behavior. The present study investigated the mechanism by which this system is endogenously activated during sexual behavior. Specifically, the effects of sexual experience and sex-related environmental cues on the activation of several components of the mesolimbic system were studied. The mesolimbic system consists of a dopaminergic projection from the ventral tegmental area (VTA) to the nucleus accumbens (NAc). Previous studies suggest that these neurons are under tonic inhibition by local GABA interneurons, which are in turn modulated by mu opioid receptor (MOR) ligands. To test the hypothesis that opioids are acting in the VTA during sexual behavior, visualization of MOR internalization in VTA was used as a marker for ligand-induced activation of the receptor. Significant increases in MOR internalization were observed following copulation or exposure to sex-related environmental cues. The next goal was to determine if sexual behavior activates dopamine neurons in the VTA, using tyrosine hydroxylase as a marker for dopaminergic neurons and Fos-immunoreactivity as a marker for neuronal activation. Significant increases in the percentage of activated dopaminergic neurons were observed following copulation or exposure to sex-related environmental cues. In addition, mating and sex-related cues activated a large population of nondopaminergic neurons in VTA as well as neurons in both the NAc Core and Shell. Taken together, our results provide functional neuroanatomical evidence that the mesolimbic system is activated by both sexual behavior and exposure to sex-related environmental cues.

White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package

DTIC Science & Technology

2015-12-01

Rack Mount System Mechanical Drawing Package by Steven P Callaway Approved for public release; distribution unlimited...Laboratory White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package by Steven P...Note 3. DATES COVERED (From - To) 04/2013 4. TITLE AND SUBTITLE White House Communications Agency (WHCA) Presidential Voice Communications Rack

Individual differences in anticipatory activity to food rewards predict cue-induced appetitive 50-kHz calls in rats.

PubMed

Brenes, Juan C; Schwarting, Rainer K W

2015-10-01

Reward-related stimuli come to acquire incentive salience through Pavlovian learning and become capable of controlling reward-oriented behaviors. Here, we examined individual differences in anticipatory activity elicited by reward-related cues as indicative of how animals attribute incentive salience to otherwise neutral stimuli. Since adult rats can signal incentive motivation states through ultrasonic vocalizations (USVs) at around 50-kHz, such calls were recorded in food-deprived rats trained to associate cues with food rewards, which were subsequently devalued by satiation.We found that the extent to which animals developed conditioned anticipatory activity to food cues while food deprived determined the level of cue-induced appetitive USVs while sated. Re-exposure to reward cues after a free-testing period reinstated USVs, invigorated reward seeking and consumption, and again, increases in calling occurred only in animals with high levels of cue-induced anticipatory activity. Reward-experienced rats systemically challenged with the catecholamine agonist amphetamine or with the dopamine receptor antagonist flupenthixol showed attenuated responses to these drugs, especially for USVs and in subjects with high levels of cue-induced anticipatory activity. Our results suggest that individuals prone to attribute incentive salience to reward cues showed heightened reward-induced USVs which were reliably expressed over time and persisted despite physiological needs being fulfilled. Also, prone subjects seemed to undergo particular adaptations in their dopaminergic system related with incentive learning. Our findings may have translational relevance in preclinical research modeling compulsive disorders, which may be due to excessive attribution of incentive salience to reward cues, such as overeating, pathological gambling, and drug addiction.

Crozier's paradox revisited: maintenance of genetic recognition systems by disassortative mating.

PubMed

Holman, Luke; van Zweden, Jelle S; Linksvayer, Timothy A; d'Ettorre, Patrizia

2013-09-27

Organisms are predicted to behave more favourably towards relatives, and kin-biased cooperation has been found in all domains of life from bacteria to vertebrates. Cooperation based on genetic recognition cues is paradoxical because it disproportionately benefits individuals with common phenotypes, which should erode the required cue polymorphism. Theoretical models suggest that many recognition loci likely have some secondary function that is subject to diversifying selection, keeping them variable. Here, we use individual-based simulations to investigate the hypothesis that the dual use of recognition cues to facilitate social behaviour and disassortative mating (e.g. for inbreeding avoidance) can maintain cue diversity over evolutionary time. Our model shows that when organisms mate disassortatively with respect to their recognition cues, cooperation and recognition locus diversity can persist at high values, especially when outcrossed matings produce more surviving offspring. Mating system affects cue diversity via at least four distinct mechanisms, and its effects interact with other parameters such as population structure. Also, the attrition of cue diversity is less rapid when cooperation does not require an exact cue match. Using a literature review, we show that there is abundant empirical evidence that heritable recognition cues are simultaneously used in social and sexual behaviour. Our models show that mate choice is one possible resolution of the paradox of genetic kin recognition, and the literature review suggests that genetic recognition cues simultaneously inform assortative cooperation and disassortative mating in a large range of taxa. However, direct evidence is scant and there is substantial scope for future work.

Eliciting nicotine craving with virtual smoking cues.

PubMed

Gamito, Pedro; Oliveira, Jorge; Baptista, André; Morais, Diogo; Lopes, Paulo; Rosa, Pedro; Santos, Nuno; Brito, Rodrigo

2014-08-01

Craving is a strong desire to consume that emerges in every case of substance addiction. Previous studies have shown that eliciting craving with an exposure cues protocol can be a useful option for the treatment of nicotine dependence. Thus, the main goal of this study was to develop a virtual platform in order to induce craving in smokers. Fifty-five undergraduate students were randomly assigned to two different virtual environments: high arousal contextual cues and low arousal contextual cues scenarios (17 smokers with low nicotine dependency were excluded). An eye-tracker system was used to evaluate attention toward these cues. Eye fixation on smoking-related cues differed between smokers and nonsmokers, indicating that smokers focused more often on smoking-related cues than nonsmokers. Self-reports of craving are in agreement with these results and suggest a significant increase in craving after exposure to smoking cues. In sum, these data support the use of virtual environments for eliciting craving.

Helicopter Flight Simulation Motion Platform Requirements

NASA Technical Reports Server (NTRS)

Schroeder, Jeffery Allyn

1999-01-01

To determine motion fidelity requirements, a series of piloted simulations was performed. Several key results were found. First, lateral and vertical translational platform cues had significant effects on fidelity. Their presence improved performance and reduced pilot workload. Second, yaw and roll rotational platform cues were not as important as the translational platform cues. In particular, the yaw rotational motion platform cue did not appear at all useful in improving performance or reducing workload. Third, when the lateral translational platform cue was combined with visual yaw rotational cues, pilots believed the platform was rotating when it was not. Thus, simulator systems can be made more efficient by proper combination of platform and visual cues. Fourth, motion fidelity specifications were revised that now provide simulator users with a better prediction of motion fidelity based upon the frequency responses of their motion control laws. Fifth, vertical platform motion affected pilot estimates of steady-state altitude during altitude repositioning. Finally, the combined results led to a general method for configuring helicopter motion systems and for developing simulator tasks that more likely represent actual flight. The overall results can serve as a guide to future simulator designers and to today's operators.

Systems and methods for mirror mounting with minimized distortion

NASA Technical Reports Server (NTRS)

Antonille, Scott R. (Inventor); Wallace, Thomas E. (Inventor); Content, David A. (Inventor); Wake, Shane W. (Inventor)

2012-01-01

A method for mounting a mirror for use in a telescope includes attaching the mirror to a plurality of adjustable mounts; determining a distortion in the mirror caused by the plurality adjustable mounts, and, if the distortion is determined to be above a predetermined level: adjusting one or more of the adjustable mounts; and determining the distortion in the mirror caused by the adjustable mounts; and in the event the determined distortion is determined to be at or below the predetermined level, rigidizing the adjustable mounts.

New human-centered linear and nonlinear motion cueing algorithms for control of simulator motion systems

NASA Astrophysics Data System (ADS)

Telban, Robert J.

While the performance of flight simulator motion system hardware has advanced substantially, the development of the motion cueing algorithm, the software that transforms simulated aircraft dynamics into realizable motion commands, has not kept pace. To address this, new human-centered motion cueing algorithms were developed. A revised "optimal algorithm" uses time-invariant filters developed by optimal control, incorporating human vestibular system models. The "nonlinear algorithm" is a novel approach that is also formulated by optimal control, but can also be updated in real time. It incorporates a new integrated visual-vestibular perception model that includes both visual and vestibular sensation and the interaction between the stimuli. A time-varying control law requires the matrix Riccati equation to be solved in real time by a neurocomputing approach. Preliminary pilot testing resulted in the optimal algorithm incorporating a new otolith model, producing improved motion cues. The nonlinear algorithm vertical mode produced a motion cue with a time-varying washout, sustaining small cues for longer durations and washing out large cues more quickly compared to the optimal algorithm. The inclusion of the integrated perception model improved the responses to longitudinal and lateral cues. False cues observed with the NASA adaptive algorithm were absent. As a result of unsatisfactory sensation, an augmented turbulence cue was added to the vertical mode for both the optimal and nonlinear algorithms. The relative effectiveness of the algorithms, in simulating aircraft maneuvers, was assessed with an eleven-subject piloted performance test conducted on the NASA Langley Visual Motion Simulator (VMS). Two methods, the quasi-objective NASA Task Load Index (TLX), and power spectral density analysis of pilot control, were used to assess pilot workload. TLX analysis reveals, in most cases, less workload and variation among pilots with the nonlinear algorithm. Control input analysis shows pilot-induced oscillations on a straight-in approach are less prevalent compared to the optimal algorithm. The augmented turbulence cues increased workload on an offset approach that the pilots deemed more realistic compared to the NASA adaptive algorithm. The takeoff with engine failure showed the least roll activity for the nonlinear algorithm, with the least rudder pedal activity for the optimal algorithm.

Depth Cue Integration in an Active Control Paradigm

NASA Technical Reports Server (NTRS)

Kaiser, Mary K.; Sweet, Barabara T.; Shafto, Meredith; Null, Cynthia H. (Technical Monitor)

1995-01-01

Numerous models of depth cue integration have been proposed. Of particular interest is how the visual system processes discrepent cues, as might arise when viewing synthetic displays. A powerful paradigm for examining this integration process can be adapted from manual control research. This methodology introduces independent disturbances in the candidate cues, then performs spectral analysis of subjects' resulting motoric responses (e.g., depth matching). We will describe this technique and present initial findings.

An Overview of Psycholinguistic Reading Theory.

ERIC Educational Resources Information Center

Hayes, Christopher G.

In the most adequate psycholinguistic model of the reading process the proficient silent reader decodes directly from graphic surface structure into deep structure, with no decoding into oral surface structure. Three cue systems used by all proficient readers include graphic cues (letters and words), syntactic cues (the grammatical arrangement of…

The Effects of Explicit Visual Cues in Reading Biological Diagrams

ERIC Educational Resources Information Center

Ge, Yun-Ping; Unsworth, Len; Wang, Kuo-Hua

2017-01-01

Drawing on cognitive theories, this study intends to investigate the effects of explicit visual cues which have been proposed as a critical factor in facilitating understanding of biological images. Three diagrams from Taiwanese textbooks with implicit visual cues, involving the concepts of biological classification systems, fish taxonomy, and…

Assessing the Structural, Driver and Economic Impacts of Traffic Pole Mounted Wind Power Generator and Solar Panel Hybrid System

DOT National Transportation Integrated Search

2012-06-01

This project evaluates the physical and economic feasibility of using existing traffic infrastructure to mount wind power : generators. Some possible places to mount a light weight wind generator and solar panel hybrid system are: i) Traffic : signal...

The research on a novel type of the solar-blind UV head-mounted displays

NASA Astrophysics Data System (ADS)

Zhao, Shun-long

2011-08-01

Ultraviolet technology of detecting is playing a more and more important role in the field of civil application, especially in the corona discharge detection, in modern society. Now the UV imaging detector is one of the most important equipments in power equipment flaws detection. And the modern head-mounted displays (HMDs) have shown the applications in the fields of military, industry production, medical treatment, entertainment, 3D visualization, education and training. We applied the system of head-mounted displays to the UV image detection, and a novel type of head-mounted displays is presented: the solar-blind UV head-mounted displays. And the structure is given. By the solar-blind UV head-mounted displays, a real-time, isometric and visible image of the corona discharge is correctly displayed upon the background scene where it exists. The user will see the visible image of the corona discharge on the real scene rather than on a small screen. Then the user can easily find out the power equipment flaws and repair them. Compared with the traditional UV imaging detector, the introducing of the HMDs simplifies the structure of the whole system. The original visible spectrum optical system is replaced by the eye in the solar-blind UV head-mounted displays. And the optical image fusion technology would be used rather than the digital image fusion system which is necessary in traditional UV imaging detector. That means the visible spectrum optical system and digital image fusion system are not necessary. This makes the whole system cheaper than the traditional UV imaging detector. Another advantage of the solar-blind UV head-mounted displays is that the two hands of user will be free. So while observing the corona discharge the user can do some things about it. Therefore the solar-blind UV head-mounted displays can make the corona discharge expose itself to the user in a better way, and it will play an important role in corona detection in the future.

Context controls access to working and reference memory in the pigeon (Columba livia).

PubMed

Roberts, William A; Macpherson, Krista; Strang, Caroline

2016-01-01

The interaction between working and reference memory systems was examined under conditions in which salient contextual cues were presented during memory retrieval. Ambient colored lights (red or green) bathed the operant chamber during the presentation of comparison stimuli in delayed matching-to-sample training (working memory) and during the presentation of the comparison stimuli as S+ and S- cues in discrimination training (reference memory). Strong competition between memory systems appeared when the same contextual cue appeared during working and reference memory training. When different contextual cues were used, however, working memory was completely protected from reference memory interference. © 2016 Society for the Experimental Analysis of Behavior.

Vertical repositioning accuracy of magnetic mounting systems on 4 articulator models.

PubMed

Lee, Wonsup; Kwon, Ho-Beom

2018-03-01

Research of the ability of a cast mounted on an articulator on maintaining the identical position of a cast mounted on an articulator after repeated repositioning is lacking, despite the possible effects this may have on the occlusion of a mounted cast. The purpose of this in vitro study was to verify and compare the vertical repositioning accuracy of 4 different, commercially available articulator magnetic mounting plate systems. Four articulators and their associated magnetic mounting plates were selected for the study. These were the Artex AR articulator (Amann Girrbach AG), the Denar Mark II articulator (Whip Mix Corp), the Kavo Protar Evo articulator (Kavo Dental GmbH), and the SAM3 articulator (SAM Präzisionstechnik GmbH). Three new magnetic mounting plates were prepared for each articulator system. The repositioning accuracy of each mounting plate was evaluated by comparing the standard deviation of the vertical distances measured between the mounting plate and a laser displacement sensor. The lower arm of the articulator was secured, and the vertical distance was measured by positioning the laser displacement sensor positioned vertically above the mounting plate. Once the vertical distance was measured, the mounting plate was detached from the articulator and reattached manually to prepare for the next measurement. This procedure was repeated 30 times for each of the 3 magnetic mounting plates. Data were analyzed by ANOVA for 2-stage nested design and the Levene test (α=.05). Significant differences were detected among articulator systems and between magnetic mounting plates of the same type. The standard deviations of the measurements made with the Artex AR articulator, Denar Mark II articulator, Kavo Protar Evo articulator, and SAM3 articulator were 0.0027, 0.0308, 0.0214, and 0.0215 mm, respectively. Thus, the repositioning accuracy could be ranked in the order as follows: Artex AR, Kavo Protar Evo, SAM3, and Denar Mark II. The position of the magnetic mounting plate after repositioning did not maintain an identical position in the vertical dimension on any of the 4 articulator models tested. The repositioning accuracy of the mounting plates showed significant differences among the articulators tested in this study. Copyright © 2017 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

Visual cues in low-level flight - Implications for pilotage, training, simulation, and enhanced/synthetic vision systems

NASA Technical Reports Server (NTRS)

Foyle, David C.; Kaiser, Mary K.; Johnson, Walter W.

1992-01-01

This paper reviews some of the sources of visual information that are available in the out-the-window scene and describes how these visual cues are important for routine pilotage and training, as well as the development of simulator visual systems and enhanced or synthetic vision systems for aircraft cockpits. It is shown how these visual cues may change or disappear under environmental or sensor conditions, and how the visual scene can be augmented by advanced displays to capitalize on the pilot's excellent ability to extract visual information from the visual scene.

Extracting Social Information from Chemosensory Cues: Consideration of Several Scenarios and Their Functional Implications

PubMed Central

Ben-Shaul, Yoram

2015-01-01

Across all sensory modalities, stimuli can vary along multiple dimensions. Efficient extraction of information requires sensitivity to those stimulus dimensions that provide behaviorally relevant information. To derive social information from chemosensory cues, sensory systems must embed information about the relationships between behaviorally relevant traits of individuals and the distributions of the chemical cues that are informative about these traits. In simple cases, the mere presence of one particular compound is sufficient to guide appropriate behavior. However, more generally, chemosensory information is conveyed via relative levels of multiple chemical cues, in non-trivial ways. The computations and networks needed to derive information from multi-molecule stimuli are distinct from those required by single molecule cues. Our current knowledge about how socially relevant information is encoded by chemical blends, and how it is extracted by chemosensory systems is very limited. This manuscript explores several scenarios and the neuronal computations required to identify them. PMID:26635515

User's guide for a revised computer program to analyze the LRC 16 foot transonic dynamics tunnel active cable mount system. [computer techniques - aircraft models

NASA Technical Reports Server (NTRS)

Chin, J.; Barbero, P.

1975-01-01

The revision of an existing digital program to analyze the stability of models mounted on a two-cable mount system used in a transonic dynamics wind tunnel is presented. The program revisions and analysis of an active feedback control system to be used for controlling the free-flying models are treated.

Steering intermediate courses: desert ants combine information from various navigational routines.

PubMed

Wehner, Rüdiger; Hoinville, Thierry; Cruse, Holk; Cheng, Ken

2016-07-01

A number of systems of navigation have been studied in some detail in insects. These include path integration, a system that keeps track of the straight-line distance and direction travelled on the current trip, the use of panoramic landmarks and scenery for orientation, and systematic searching. A traditional view is that only one navigational system is in operation at any one time, with different systems running in sequence depending on the context and conditions. We review selected data suggesting that often, different navigational cues (e.g., compass cues) and different systems of navigation are in operation simultaneously in desert ant navigation. The evidence suggests that all systems operate in parallel forming a heterarchical network. External and internal conditions determine the weights to be accorded to each cue and system. We also show that a model of independent modules feeding into a central summating device, the Navinet model, can in principle account for such data. No central executive processor is necessary aside from a weighted summation of the different cues and systems. Such a heterarchy of parallel systems all in operation represents a new view of insect navigation that has already been expressed informally by some authors.

Design of a new engine mount for vertical and horizontal vibration control using magnetorheological fluid

NASA Astrophysics Data System (ADS)

Phu, D. X.; Choi, S. B.; Lee, Y. S.; Han, M. S.

2014-10-01

This paper presents a new design of a magnetorheological fluid (MR) mount for vibration control considering both vertical forces and horizontal moments such as are met in various engine systems, including a medium high-speed engine of ship. The newly designed mount, called a MR brake mount, offers several salient benefits such as small size and relatively high load capacity compared with a conventional MR engine mount that can control vertical vibration only. The principal design parameters of the proposed mount are optimally determined to achieve maximum torque with geometric and spatial constraints. Subsequently, the proposed MR mount is designed and manufactured based on the optimized design parameters. It is shown from experimental testing that the proposed mount, which combines MR mount with MR brake, can produce the desired force and torque to reduce unwanted vibration of a medium high-speed engine system of ship subjected to both vertical and horizontal exciting motions. In addition, it is verified that there is no large difference between experiment results and simulation results that are obtained from an analytical model derived in this work.

An improved loopless mounting method for cryocrystallography

NASA Astrophysics Data System (ADS)

Qi, Jian-Xun; Jiang, Fan

2010-01-01

Based on a recent loopless mounting method, a simplified loopless and bufferless crystal mounting method is developed for macromolecular crystallography. This simplified crystal mounting system is composed of the following components: a home-made glass capillary, a brass seat for holding the glass capillary, a flow regulator, and a vacuum pump for evacuation. Compared with the currently prevalent loop mounting method, this simplified method has almost the same mounting procedure and thus is compatible with the current automated crystal mounting system. The advantages of this method include higher signal-to-noise ratio, more accurate measurement, more rapid flash cooling, less x-ray absorption and thus less radiation damage to the crystal. This method can be extended to the flash-freeing of a crystal without or with soaking it in a lower concentration of cryoprotectant, thus it may be the best option for data collection in the absence of suitable cryoprotectant. Therefore, it is suggested that this mounting method should be further improved and extensively applied to cryocrystallographic experiments.

Effect of structural flexibility on the design of vibration-isolating mounts for aircraft engines

NASA Technical Reports Server (NTRS)

Phillips, W. H.

1984-01-01

Previous analyses of the design of vibration-isolating mounts for a rear-mounted engine to decouple linear and rotational oscillations are extended to take into account flexibility of the engine-mount structure. Equations and curves are presented to allow the design of mount systems and to illustrate the results for a range of design conditions.

Control of Prose Processing via Instructional and Typographical Cues.

ERIC Educational Resources Information Center

Glynn, Shawn M.; Di Vesta, Francis J.

1979-01-01

College students studied text about an imaginary solar system. Two cuing systems were manipulated to induce a single or double set of cues consistent with one or two sets of text propositions, or no target propositions were specified. Cuing systems guided construction and implementation of prose-processing decision criteria. (Author/RD)

14 CFR 29.1163 - Powerplant accessories.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine involved; (2) Use the provisions on the engine for mounting; and (3) Be sealed in such a way as to prevent contamination of the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or...

14 CFR 29.1163 - Powerplant accessories.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine involved; (2) Use the provisions on the engine for mounting; and (3) Be sealed in such a way as to prevent contamination of the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or...

14 CFR 29.1163 - Powerplant accessories.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine involved; (2) Use the provisions on the engine for mounting; and (3) Be sealed in such a way as to prevent contamination of the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or...

14 CFR 29.1163 - Powerplant accessories.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine involved; (2) Use the provisions on the engine for mounting; and (3) Be sealed in such a way as to prevent contamination of the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or...

Vibration isolation mounting system

NASA Technical Reports Server (NTRS)

Carter, Sam D. (Inventor); Bastin, Paul H. (Inventor)

1995-01-01

A system is disclosed for mounting a vibration producing device onto a spacecraft structure and also for isolating the vibration forces thereof from the structure. The system includes a mount on which the device is securely mounted and inner and outer rings. The rings and mount are concentrically positioned. The system includes a base (secured to the structure) and a set of links which are interconnected by a set of torsion bars which allow and resist relative rotational movement therebetween. The set of links are also rotatably connected to a set of brackets which are rigidly connected to the outer ring. Damped leaf springs interconnect the inner and outer rings and the mount allow relative translational movement therebetween in X and Y directions. The links, brackets and base are interconnected and configured so that they allow and resist translational movement of the device in the Z direction so that in combination with the springs they provide absorption of vibrational energy produced by the device in all three dimensions while providing rotational stiffness about all three axes to prevent undesired rotational motions.

Dread of uncertain pain: An event-related potential study

PubMed Central

Huang, Yujing; Shang, Qian; Dai, Shenyi; Ma, Qingguo

2017-01-01

Humans experience more stress about uncertain situations than certain situations. However, the neural mechanism underlying the uncertainty of a negative stimulus has not been determined. In the present study, event-related potential was recorded to examine neural responses during the dread of unpredictable pain. We used a cueing paradigm in which predictable cues were always followed by electric shocks, unpredictable cues by electric shocks at a 50/50 ratio and safe cues by no electric shock. Visual analogue scales following electric shocks were presented to quantify subjective anxiety levels. The behavioral results showed that unpredictable cues evoked high-level anxiety compared with predictable cues in both painful and unpainful stimulation conditions. More importantly, the ERPs results revealed that unpredictable cues elicited a larger P200 at parietal sites than predictable cues. In addition, unpredictable cues evoked larger P200 compared with safe cues at frontal electrodes and compared with predictable cues at parietal electrodes. In addition, larger P3b and LPP were observed during perception of safe cues compared with predictable cues at frontal and central electrodes. The similar P3b effect was also revealed in the left sites. The present study underlined that the uncertain dread of pain was associated with threat appraisal process in pain system. These findings on early event-related potentials were significant for a neural marker and development of therapeutic interventions. PMID:28832607

Forgotten but not gone: Retro-cue costs and benefits in a double-cueing paradigm suggest multiple states in visual short-term memory.

PubMed

van Moorselaar, Dirk; Olivers, Christian N L; Theeuwes, Jan; Lamme, Victor A F; Sligte, Ilja G

2015-11-01

Visual short-term memory (VSTM) performance is enhanced when the to-be-tested item is cued after encoding. This so-called retro-cue benefit is typically accompanied by a cost for the noncued items, suggesting that information is lost from VSTM upon presentation of a retrospective cue. Here we assessed whether noncued items can be restored to VSTM when made relevant again by a subsequent second cue. We presented either 1 or 2 consecutive retro-cues (80% valid) during the retention interval of a change-detection task. Relative to no cue, a valid cue increased VSTM capacity by 2 items, while an invalid cue decreased capacity by 2. Importantly, when a second, valid cue followed an invalid cue, capacity regained 2 items, so that performance was back on par. In addition, when the second cue was also invalid, there was no extra loss of information from VSTM, suggesting that those items that survived a first invalid cue, automatically also survived a second. We conclude that these results are in support of a very versatile VSTM system, in which memoranda adopt different representational states depending on whether they are deemed relevant now, in the future, or not at all. We discuss a neural model that is consistent with this conclusion. (c) 2015 APA, all rights reserved).

The Effect of a Monocular Helmet-Mounted Display on Aircrew Health: A Cohort Study of Apache AH Mk 1 Pilots Four-Year Review

DTIC Science & Technology

2009-12-01

forward-looking infrared FOV field-of-view HDU helmet display unit HMD helmet-mounted display IHADSS Integrated Helmet and Display...monocular Integrated Helmet and Display Sighting System (IHADSS) helmet-mounted display ( HMD ) in the British Army’s Apache AH Mk 1 attack helicopter has any...Integrated Helmet and Display Sighting System, IHADSS, Helmet-mounted display, HMD , Apache helicopter, Visual performance UNCLAS UNCLAS UNCLAS SAR 96

Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system.

PubMed

Swinford-Jackson, S E; Anastasio, N C; Fox, R G; Stutz, S J; Cunningham, K A

2016-06-02

Intensification of craving elicited by drug-associated cues during abstinence occurs over time in human cocaine users while elevation of cue reactivity ("incubation") is observed in rats exposed to extended forced abstinence from cocaine self-administration. Incubation in rodents has been linked to time-dependent neuronal plasticity in the medial prefrontal cortex (mPFC). We tested the hypothesis that incubation of cue reactivity during abstinence from cocaine self-administration is accompanied by lower potency and/or efficacy of the selective serotonin (5-HT) 5-HT2C​ receptor (5-HT2CR) agonist WAY163909 to suppress cue reactivity and a shift in the subcellular localization profile of the mPFC 5-HT2CR protein. We observed incubation of cue reactivity (measured as lever presses reinforced by the discrete cue complex) between Day 1 and Day 30 of forced abstinence from cocaine relative to sucrose self-administration. Pharmacological and biochemical analyses revealed that the potency of the selective 5-HT2CR agonist WAY163909 to suppress cue reactivity, the expression of synaptosomal 5-HT2CR protein in the mPFC, and the membrane to cytoplasmic expression of the 5-HT2CR in mPFC were lower on Day 30 vs. Day 1 of forced abstinence from cocaine self-administration. Incubation of cue reactivity assessed during forced abstinence from sucrose self-administration did not associate with 5-HT2CR protein expression in the mPFC. Collectively, these outcomes are the first indication that neuroadaptations in the 5-HT2CR system may contribute to incubation of cocaine cue reactivity. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT2C receptor (5-HT2CR) system

PubMed Central

Swinford-Jackson, Sarah E.; Anastasio, Noelle C.; Fox, Robert G.; Stutz, Sonja J.; Cunningham, Kathryn A.

2016-01-01

Intensification of craving elicited by drug-associated cues during abstinence occurs over time in human cocaine users while elevation of cue reactivity (“incubation”) is observed in rats exposed to extended forced abstinence from cocaine self-administration. Incubation in rodents has been linked to time-dependent neuronal plasticity in the medial prefrontal cortex (mPFC). We tested the hypothesis that incubation of cue reactivity during abstinence from cocaine self-administration is accompanied by lower potency and/or efficacy of the selective 5-HT2CR agonist WAY163909 to suppress cue reactivity and a shift in the subcellular localization profile of the mPFC 5-HT2CR protein. We observed incubation of cue reactivity (measured as lever presses reinforced by the discrete cue complex) between Day 1 and Day 30 of forced abstinence from cocaine relative to sucrose self-administration. Pharmacological and biochemical analyses revealed that the potency of the selective 5-HT2CR agonist WAY163909 to suppress cue reactivity, the expression of synaptosomal 5-HT2CR protein in the mPFC, and the membrane to cytoplasmic expression of the 5-HT2CR in mPFC were lower on Day 30 vs. Day 1 of forced abstinence from cocaine self-administration. Incubation of cue reactivity assessed during forced abstinence from sucrose self-administration did not associate with 5-HT2CR protein expression in the mPFC. Collectively, these outcomes are the first indication that neuroadaptations in the 5-HT2CR system may contribute to incubation of cocaine cue reactivity. PMID:26926963

Orexin / hypocretin signaling at the OX1 receptor regulates cue-elicited cocaine-seeking

PubMed Central

Smith, Rachel J.; See, Ronald E.; Aston-Jones, Gary

2009-01-01

The orexin / hypocretin system has recently been implicated in reward-processing and addiction. We examined the involvement of the orexin system in cue-induced reinstatement of extinguished cocaine-seeking by administering the orexin 1 receptor (OX1R) antagonist SB-334867, or the orexin 2 receptor (OX2R) antagonist 4-pyridylmethyl (S)-tert-leucyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (4PT), prior to reinstatement testing. Male Sprague-Dawley rats self-administered cocaine in 2-hour sessions for 10 days, followed by extinction training. Reinstatement of cocaine-seeking was elicited by presentation of tone + light cues previously paired with cocaine infusions. SB-334867 (10, 20, 30 mg/kg) dose-dependently decreased cue-induced reinstatement of cocaine-seeking without significantly affecting responding during late extinction. 4PT (10, 30 mg/kg) did not significantly alter cue-induced reinstatement. In separate experiments, the highest doses of SB-334867 and 4PT had no significant effect on established cocaine self-administration, and 4PT reduced spontaneous activity in a locomotor test to a greater extent than SB-334867. Finally, SB-334867 (30 mg/kg) had no effect on the acquisition of cocaine-paired cues during a Pavlovian cocaine-stimulus conditioning session in the operant chamber. Pretreatment with SB-334867 prior to the Pavlovian acquisition session had no effect on subsequent cue-induced reinstatement of cocaine-seeking elicited by those cues. However, pretreatment with SB-334867 prior to a second reinstatement session significantly attenuated the expression of cue-induced reinstatement. These results show that orexin transmission at OX1R, but not OX2R, is necessary for the reinstatement of cocaine-seeking elicited by drug-paired cues, and that orexin signaling is not critical for cocaine reinforcement or cocaine-stimulus conditioning. PMID:19656173

A System of Deception and Fraud Detection Using Reliable Linguistic Cues Including Hedging, Disfluencies, and Repeated Phrases

ERIC Educational Resources Information Center

Humpherys, Sean LaMarc

2010-01-01

Given the increasing problem of fraud, crime, and national security threats, assessing credibility is a recurring research topic in Information Systems and in other disciplines. Decision support systems can help. But the success of the system depends on reliable cues that can distinguish deceptive/truthful behavior and on a proven classification…

Optical mounts for harsh environments

NASA Astrophysics Data System (ADS)

Mimovich, Mark E.; Griffee, Jonathan C.; Goodding, James C.

2009-08-01

Development and testing of a lightweight-kinematic optical mount with integrated passive vibration-and-shock mitigation technologies and simple / robust optical alignment functionality is presented. Traditionally, optical mounts are designed for use in laboratory environments where the thermal-mechanical environments are carefully controlled to preserve beam path conditions and background disturbances are minimized to facilitate precise optically based measurements. Today's weapon and surveillance systems, however, have optical sensor suites where static and dynamic alignment performance in the presence of harsh operating environments is required to nearly the same precision and where the system cannot afford the mass of laboratory-grade stabilized mounting systems. Jitter and alignment stability is particularly challenging for larger optics operating within moving vehicles and aircraft where high shock and significant temperature excursions occur. The design intent is to have the mount be suitable for integration into existing defense and security optical systems while also targeting new commercial and military components for improved structural dynamic and thermal distortion performance. A mount suitable for moderate-sized optics and an integrated disturbance-optical metrology system are described. The mount design has performance enhancements derived from the integration of proven aerospace mechanical vibration and shock mitigation technologies (i.e. multi-axis passive isolation and integral damping), precision alignment adjustment and lock-out functionality, high dimensional stability materials and design practices which provide benign optical surface figure errors under harsh thermal-mechanical loading. Optical jitter, alignment, and wave-front performance testing of an eight-inch-aperture optical mount based on this design approach are presented to validate predicted performance improvements over an existing commercial off-the-shelf (COTS) design.

Improved memory for reward cues following acute buprenorphine administration in humans.

PubMed

Syal, Supriya; Ipser, Jonathan; Terburg, David; Solms, Mark; Panksepp, Jaak; Malcolm-Smith, Susan; Bos, Peter A; Montoya, Estrella R; Stein, Dan J; van Honk, Jack

2015-03-01

In rodents, there is abundant evidence for the involvement of the opioid system in the processing of reward cues, but this system has remained understudied in humans. In humans, the happy facial expression is a pivotal reward cue. Happy facial expressions activate the brain's reward system and are disregarded by subjects scoring high on depressive mood who are low in reward drive. We investigated whether a single 0.2mg administration of the mixed mu-opioid agonist/kappa-antagonist, buprenorphine, would influence short-term memory for happy, angry or fearful expressions relative to neutral faces. Healthy human subjects (n38) participated in a randomized placebo-controlled within-subject design, and performed an emotional face relocation task after administration of buprenorphine and placebo. We show that, compared to placebo, buprenorphine administration results in a significant improvement of memory for happy faces. Our data demonstrate that acute manipulation of the opioid system by buprenorphine increases short-term memory for social reward cues. Copyright © 2015. Published by Elsevier Ltd.

Using PVFORM, a systems performance model, to determine optimum mounting configurations for flat-plate photovoltaic modules

NASA Astrophysics Data System (ADS)

Menicucci, D. F.

The performance of a photovoltaic (PV) system is affected by the particular mounting configuration selected. But the optimal configuration for various potential designs is unknown because too few PV systems have been fielded. Sandia National Laboratories (SNLA) is currently conducting a controlled field experiment in which four of the most commonly used module mounting configurations are being compared. The data from the experiment are used to verify the accuracy of PVFORM, a new PV performance model. The model is then used to simulate the performance of PV modules mounted in different configurations in eight sites throughtout the U.S. The module mounting configurations, the experimental methods used, the specialized statistical techniques used in the analysis and the final results of the effort are described. The module mounting configurations are rank ordered at each site according to their energy production performane and each is briefly discussed in terms of its advantages or disadvantages in various applications.

Role of somatosensory and vestibular cues in attenuating visually induced human postural sway

NASA Technical Reports Server (NTRS)

Peterka, Robert J.; Benolken, Martha S.

1993-01-01

The purpose was to determine the contribution of visual, vestibular, and somatosensory cues to the maintenance of stance in humans. Postural sway was induced by full field, sinusoidal visual surround rotations about an axis at the level of the ankle joints. The influences of vestibular and somatosensory cues were characterized by comparing postural sway in normal and bilateral vestibular absent subjects in conditions that provided either accurate or inaccurate somatosensory orientation information. In normal subjects, the amplitude of visually induced sway reached a saturation level as stimulus amplitude increased. The saturation amplitude decreased with increasing stimulus frequency. No saturation phenomena was observed in subjects with vestibular loss, implying that vestibular cues were responsible for the saturation phenomenon. For visually induced sways below the saturation level, the stimulus-response curves for both normal and vestibular loss subjects were nearly identical implying that (1) normal subjects were not using vestibular information to attenuate their visually induced sway, possibly because sway was below a vestibular-related threshold level, and (2) vestibular loss subjects did not utilize visual cues to a greater extent than normal subjects; that is, a fundamental change in visual system 'gain' was not used to compensate for a vestibular deficit. An unexpected finding was that the amplitude of body sway induced by visual surround motion could be almost three times greater than the amplitude of the visual stimulus in normals and vestibular loss subjects. This occurred in conditions where somatosensory cues were inaccurate and at low stimulus amplitudes. A control system model of visually induced postural sway was developed to explain this finding. For both subject groups, the amplitude of visually induced sway was smaller by a factor of about four in tests where somatosensory cues provided accurate versus inaccurate orientation information. This implied that (1) the vestibular loss subjects did not utilize somatosensory cues to a greater extent than normal subjects; that is, changes in somatosensory system 'gain' were not used to compensate for a vestibular deficit, and (2) the threshold for the use of vestibular cues in normals was apparently lower in test conditions where somatosensory cues were providing accurate orientation information.

Experience-Dependent Effects of Cocaine Self-Administration/Conditioning on Prefrontal and Accumbens Dopamine Responses

PubMed Central

Ikegami, Aiko; Olsen, Christopher M.; D’Souza, Manoranjan S.; Duvauchelle, Christine L.

2008-01-01

Experiments were performed to examine the effects of cocaine self-administration and conditioning experience on operant behavior, locomotor activity, and nucleus accumbens (NAcc) and prefrontal cortex (PFC) dopamine (DA) responses. Sensory cues were paired with alternating cocaine and nonreinforcement during 12 (limited training) or 40 (long-term training) daily operant sessions. After limited training, NAcc DA responses to cocaine were significantly enhanced in the presence of cocaine-associated cues compared with nonreward cues and significantly depressed after cocaine-paired cues accompanied a nonreinforced lever response. PFC DA levels were generally nonresponsive to cues after the same training duration. However, after long-term training, cocaine-associated cues increased the magnitude of cocaine-stimulated PFC DA levels significantly over levels observed with nonreinforcement cues. Conversely, conditioned cues no longer influenced NAcc DA levels after long-term training. In addition, cocaine-stimulated locomotor activity was enhanced by cocaine-paired cues after long-term, but not after limited, training. Findings demonstrate that cue-induced cocaine expectation exerts a significant impact on dopaminergic and behavioral systems, progressing from mesolimbic to mesocortical regions and from latent to patent behaviors as cocaine and associative experiences escalate. PMID:17469929

Pavlovian Conditioning of Rat Mucosal Mast Cells to Secrete Rat Mast Cell Protease II

NASA Astrophysics Data System (ADS)

MacQueen, Glenda; Marshall, Jean; Perdue, Mary; Siegel, Shepard; Bienenstock, John

1989-01-01

Antigen (egg albumin) injections, which stimulate mucosal mast cells to secrete mediators, were paired with an audiovisual cue. After reexposure to the audiovisual cue, a mediator (rat mast cell protease II) was measured with a sensitive and specific assay. Animals reexposed to only the audiovisual cue released a quantity of protease not significantly different from animals reexposed to both the cue and the antigen; these groups released significantly more protease than animals that had received the cue and antigen in a noncontingent manner. The results support a role for the central nervous system as a functional effector of mast cell function in the allergic state.

Planning Support for Maintenance and Overhaul of Gun Weapon Systems

DTIC Science & Technology

1981-05-01

13 (shielded twin) gun mounts are targeted to receive ORDALTs 9335 and 9409. Sixty-seven ship hulls are involved in the program, for a total of 147...gun mounts (excluding four training mounts ). Seventy-three Mod 0 and seventy-four Mod 13 gun mounts are included in the program, for an estimated total ...of gun mounts included in the GWSIP. Each mount will receive one amplifier ORDALT, for a. a total of 147, and two upgraded oscillating assemblies

Vibration isolation of automotive vehicle engine using periodic mounting systems

NASA Astrophysics Data System (ADS)

Asiri, S.

2005-05-01

Customer awareness and sensitivity to noise and vibration levels have been raised through increasing television advertisement, in which the vehicle noise and vibration performance is used as the main market differentiation. This awareness has caused the transportation industry to regard noise and vibration as important criteria for improving market shares. One industry that tends to be in the forefront of the technology to reduce the levels of noise and vibration is the automobile industry. Hence, it is of practical interest to reduce the vibrations induced structural responses. The automotive vehicle engine is the main source of mechanical vibrations of automobiles. The engine is vulnerable to the dynamic action caused by engine disturbance force in various speed ranges. The vibrations of the automotive vehicle engines may cause structural failure, malfunction of other parts, or discomfort to passengers because of high level noise and vibrations. The mounts of the engines act as the transmission paths of the vibrations transmitted from the excitation sources to the body of the vehicle and passengers. Therefore, proper design and control of these mounts are essential to the attenuation of the vibration of platform structures. To improve vibration resistant capacities of engine mounting systems, vibration control techniques may be used. For instance, some passive and semi-active dissipation devices may be installed at mounts to enhance vibration energy absorbing capacity. In the proposed study, a radically different concept is presented whereby periodic mounts are considered because these mounts exhibit unique dynamic characteristics that make them act as mechanical filters for wave propagation. As a result, waves can propagate along the periodic mounts only within specific frequency bands called the "Pass Bands" and wave propagation is completely blocked within other frequency bands called the "Stop Bands". The experimental arrangements, including the design of mounting systems with plain and periodic mounts will be studied first. The dynamic characteristics of such systems will be obtained experimentally in both cases. The tests will be then carried out to study the performance characteristics of periodic mounts with geometrical and/or material periodicity. The effectiveness of the periodicity on the vibration levels of mounting systems will be demonstrated theoretically and experimentally. Finally, the experimental results will be compared with the theoretical predictions.

Visual gate for brain-computer interfaces.

PubMed

Dias, N S; Jacinto, L R; Mendes, P M; Correia, J H

2009-01-01

Brain-Computer Interfaces (BCI) based on event related potentials (ERP) have been successfully developed for applications like virtual spellers and navigation systems. This study tests the use of visual stimuli unbalanced in the subject's field of view to simultaneously cue mental imagery tasks (left vs. right hand movement) and detect subject attention. The responses to unbalanced cues were compared with the responses to balanced cues in terms of classification accuracy. Subject specific ERP spatial filters were calculated for optimal group separation. The unbalanced cues appear to enhance early ERPs related to cue visuospatial processing that improved the classification accuracy (as low as 6%) of ERPs in response to left vs. right cues soon (150-200 ms) after the cue presentation. This work suggests that such visual interface may be of interest in BCI applications as a gate mechanism for attention estimation and validation of control decisions.

Are face representations depth cue invariant?

PubMed

Dehmoobadsharifabadi, Armita; Farivar, Reza

2016-06-01

The visual system can process three-dimensional depth cues defining surfaces of objects, but it is unclear whether such information contributes to complex object recognition, including face recognition. The processing of different depth cues involves both dorsal and ventral visual pathways. We investigated whether facial surfaces defined by individual depth cues resulted in meaningful face representations-representations that maintain the relationship between the population of faces as defined in a multidimensional face space. We measured face identity aftereffects for facial surfaces defined by individual depth cues (Experiments 1 and 2) and tested whether the aftereffect transfers across depth cues (Experiments 3 and 4). Facial surfaces and their morphs to the average face were defined purely by one of shading, texture, motion, or binocular disparity. We obtained identification thresholds for matched (matched identity between adapting and test stimuli), non-matched (non-matched identity between adapting and test stimuli), and no-adaptation (showing only the test stimuli) conditions for each cue and across different depth cues. We found robust face identity aftereffect in both experiments. Our results suggest that depth cues do contribute to forming meaningful face representations that are depth cue invariant. Depth cue invariance would require integration of information across different areas and different pathways for object recognition, and this in turn has important implications for cortical models of visual object recognition.

Flight simulator with spaced visuals

NASA Technical Reports Server (NTRS)

Gilson, Richard D. (Inventor); Thurston, Marlin O. (Inventor); Olson, Karl W. (Inventor); Ventola, Ronald W. (Inventor)

1980-01-01

A flight simulator arrangement wherein a conventional, movable base flight trainer is combined with a visual cue display surface spaced a predetermined distance from an eye position within the trainer. Thus, three degrees of motive freedom (roll, pitch and crab) are provided for a visual proprioceptive, and vestibular cue system by the trainer while the remaining geometric visual cue image alterations are developed by a video system. A geometric approach to computing runway image eliminates a need to electronically compute trigonometric functions, while utilization of a line generator and designated vanishing point at the video system raster permits facile development of the images of the longitudinal edges of the runway.

Foraging strategies of dogwhelks, Nucella lapillus (L.): interacting effects of age, diet and chemical cues to the threat of predation.

PubMed

Sr Vadas, R L; Burrows, M T; Hughes, R N

1994-12-01

The effects of diet history, hunger and predation risk on short-term behavioral decisions of dogwhelks were tested in a specially designed test apparatus, termed a linear feeding array (LFA). The LFA consists of a sequential series of prey items mounted in a flume with unidirectional current directed towards a test (predatory) animal, and into which potential olfactory cues regarding predation risk are introduced. For dogwhelks the array was constructed vertically to accomodate intertidal foraging movements and is termed a vertical linear array (VLA). The behaviors exhibited by the dogwhelks were interpreted from distribution patterns in the VLA. Recent experimental studies and advances in optimal foraging theory provided the basis for the hypotheses tested in the VLA, which included: foraging and other behaviors are affected by predation, animals will avoid risk in the presence of predation threat, responses to predation threat will be proportional to the number and kinds of predator cues present, and starved animals will take greater risks than fed animals. We also test the proposition that foraging decisions are further modified by age. Three groups of juvenile and adult animals were maintained on diets of barnacles, mussels or no food (starved). The scent of crabs and damaged conspecifics served as olfactory cues to predation risk. Dogwhelks exhibited a range of behaviors in the VLA including: sheltering, searching, feeding, and aerial climbing. Distribution of animals in the tank assumed a relatively stable pattern after 2-3 h. These patterns were interpreted as the consequence of heirarchial decision making including: (i) a decision to become active, leaving the resting place or water refuge adopted during initial placement, followed by (ii) a decision to move vertically upwards or downwards, and (iii) a decision to attack prey when encountered. Analysis of movement patterns revealed that the initial decision, analogous to leaving a crevice as the tide comes in, was influenced in adults by predator cues and in juveniles by both predator cues and diet history. Perceived risk, as crab and damaged-conspecific odors, made individuals more likely to remain inactive, a risk-avoiding strategy for animals already in a refuge. Starved animals were more likely to descend into the tank and attack prey than fed animals. Our results support the hypotheses that higher-order predators affect the foraging decisions of dogwhelks and that juveniles and satiated animals are more sensitive to predation risk than starved ones. Together, these and earlier studies suggest that dogwhelks assess their environment before foraging, and that they are attuned to reducing the risks of mortality.

A Pilot/Vehicle Model Analysis of the Effects of Motion Cues on Harrier Control Tasks.

DTIC Science & Technology

1983-09-01

7 D- R136 291 A PILOT/VEHILE MODEL ANALYSIS OF THE EFFECTS OF MOTION i/i LS 91 CUES ON HARRIER C..(U) BOLT BERANEK AND NEWMAN INC CAMBRIDGE MA S...provided by well-designed platform motion systems , the actual rovement of performance or training effectiveness that results from incorporating these...for the Harrier AV-8B. The effects of providing motion cues via an idealized platform motion system or a g-seat device are predicted with the model, and

A Method to Test the Effect of Environmental Cues on Mating Behavior in Drosophila melanogaster.

PubMed

Gorter, Jenke A; Billeter, Jean-Christophe

2017-07-17

An individual's sexual drive is influenced by genotype, experience and environmental conditions. How these factors interact to modulate sexual behaviors remains poorly understood. In Drosophila melanogaster, environmental cues, such as food availability, affect mating activity offering a tractable system to investigate the mechanisms modulating sexual behavior. In D. melanogaster, environmental cues are often sensed via the chemosensory gustatory and olfactory systems. Here, we present a method to test the effect of environmental chemical cues on mating behavior. The assay consists of a small mating arena containing food medium and a mating couple. The mating frequency for each couple is continuously monitored for 24 h. Here we present the applicability of this assay to test environmental compounds from an external source through a pressurized air system as well as manipulation of the environmental components directly in the mating arena. The use of a pressurized air system is especially useful to test the effect of very volatile compounds, while manipulating components directly in the mating arena can be of value to ascertain a compound's presence. This assay can be adapted to answer questions about the influence of genetic and environmental cues on mating behavior and fecundity as well as other male and female reproductive behaviors.

Chemosensory cues of predators and competitors influence search for refuge in fruit by the coconut mite Aceria guerreronis.

PubMed

Calvet, Érica C; Lima, Debora B; Melo, José W S; Gondim, Manoel G C

2018-03-01

Organisms are adapted to recognize environmental cues that can provide information about predation risk or competition. Non-vagrant eriophyoid mites mainly avoid predation by using habitats that are difficult for predators to access (galls or confined spaces in plants) such as the meristematic region of the coconut fruit, which is inhabited by the phytophagous mites Aceria guerreronis and Steneotarsonemus concavuscutum. The objective of this study was to investigate the response of A. guerreronis to cues from the predators Neoseiulus baraki and Amblyseius largoensis in coconut fruits, cues from conspecifics (A. guerreronis injured) and cues from the phytophage S. concavuscutum. The test was carried out through the release of about 300 A. guerreronis on coconut fruits previously treated with cues from predators, conspecific or heterospecific phytophagous. We also observed the walking behaviour of A. guerreronis exposed to the same chemical cues using a video tracking system. The infestation of fruits by A. guerreronis was greater in the presence of predator cues and reduced in the presence of S. concavuscutum cues, but cues from injured conspecifics did not interfere in the infestation process. In addition, the cues also altered the walking parameters of A. guerreronis: it walked more in response to cues from predators and the heterospecific phytophage. Aceria guerreronis spent more time in activity in the treatments with clues than in the control treatment. These results suggest that A. guerreronis recognizes cues from predators and competitors and modifies its behaviour to increase its fitness.

Memory for Drug Related Visual Stimuli in Young Adult, Cocaine Dependent Polydrug Users

PubMed Central

Ray, Suchismita; Pandina, Robert; Bates, Marsha E.

2015-01-01

Background and Objectives Implicit (unconscious) and explicit (conscious) memory associations with drugs have been examined primarily using verbal cues. However, drug seeking, drug use behaviors, and relapse in chronic cocaine and other drug users are frequently triggered by viewing substance related visual cues in the environment. We thus examined implicit and explicit memory for drug picture cues to understand the relative extent to which conscious and unconscious memory facilitation of visual drug cues occurs during cocaine dependence. Methods Memory for drug related and neutral picture cues was assessed in 14 inpatient cocaine dependent polydrug users and a comparison group of 21 young adults with limited drug experience (N = 35). Participants completed picture cue exposure, free recall and recognition tasks to assess explicit memory, and a repetition priming task to assess implicit memory. Results Drug cues, compared to neutral cues were better explicitly recalled and implicitly primed, and especially so in the cocaine group. In contrast, neutral cues were better explicitly recognized, and especially in the control group. Conclusion Certain forms of explicit and implicit memory for drug cues were enhanced in cocaine users compared to controls when memory was tested a short time following cue exposure. Enhanced unconscious memory processing of drug cues in chronic cocaine users may be a behavioral manifestation of heightened drug cue salience that supports drug seeking and taking. There may be value in expanding intervention techniques to utilize cocaine users’ implicit memory system. PMID:24588421

Ion accelerator system mounting design and operating characteristics for a 5 kW 30-cm xenon ion engine

NASA Technical Reports Server (NTRS)

Aston, Graeme; Brophy, John R.

1987-01-01

Results from a series of experiments to determine the effect of accelerator grid mount geometry on the performance of the J-series ion optics assembly are described. Three mounting schemes, two flexible and one rigid, are compared for their relative ion extraction capability over a range of total accelerating voltages. The largest ion beam current, for the maximum total voltage investigated, is shown to occur using one of the flexible grid mounting geometries. However, at lower total voltages and reduced engine input power levels, the original rigid J-series ion optics accelerator grid mounts result in marginally better grid system performance at the same cold interelectrode gap.

Systemic treatment with D-fenfluramine, but not sibutramine, blocks cue-induced reinstatement of food-seeking behavior in the rat.

PubMed

Pratt, Wayne E; Ford, Ryan T

2013-11-27

Individuals struggling with obesity often have difficulty maintaining dietary regimens. One source of dietary relapse is the reinstatement of previous feeding behaviors following the presentation of cues indicating the availability of palatable but highly caloric food reward. The drugs fenfluramine and sibutramine have previously been prescribed because they enhance satiety mechanisms and decrease meal size. However, it is unclear whether these anorectic agents are also effective in blocking the cue-induced reinstatement of food-seeking behaviors. In these three experiments, we compared the effects of systemic treatment of d-fenfluramine (3mg/kg; N=10) and sibutramine (3mg/kg; N=11) with that of the D1 antagonist SCH 23390 (6μg/kg; N=11) at a dose that has previously been shown to attenuate cue-induced reinstatement. d-Fenfluramine treatment blocked the cue's ability to reinstate lever pressing as compared to the saline injection day. In contrast, sibutramine had no effect on cue-induced reinstatement; all animals reinstated their lever pressing during the first reinstatement test, and this was unaffected by sibutramine treatment. SCH 23390 treatment did not significantly reduce cue-induced reinstatement in this set of experiments. The results suggest that the motivational effects of d-fenfluramine is not limited to the promotion of satiety once a meal has been initiated, and demonstrate that some anorectic treatments may inhibit the effectiveness of conditioned cues to elicit relapse of food-seeking behavior. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

A New View on an Old Debate: Type of Cue-Conflict Manipulation and Availability of Stars Can Explain the Discrepancies between Cue-Calibration Experiments with Migratory Songbirds.

PubMed

Sjöberg, Sissel; Muheim, Rachel

2016-01-01

Migratory birds use multiple compass systems for orientation, including a magnetic, star and sun/polarized light compass. To keep these compasses in register, birds have to regularly update them with respect to a common reference. However, cue-conflict studies have revealed contradictory results on the compass hierarchy, favoring either celestial or magnetic compass cues as the primary calibration reference. Both the geomagnetic field and polarized light cues present at sunrise and sunset have been shown to play a role in compass cue integration, and evidence suggests that polarized light cues at sunrise and sunset may provide the primary calibration reference for the other compass systems. We tested whether migratory garden warblers recalibrated their compasses when they were exposed to the natural celestial cues at sunset in a shifted magnetic field, which are conditions that have been shown to be necessary for the use of a compass reference based on polarized light cues. We released the birds on the same evening under a starry sky and followed them by radio tracking. We found no evidence of compass recalibration, even though the birds had a full view of polarized light cues near the horizon at sunset during the cue-conflict exposure. Based on a meta-analysis of the available literature, we propose an extended unifying theory on compass cue hierarchy used by migratory birds to calibrate the different compasses. According to this scheme, birds recalibrate their magnetic compass by sunrise/sunset polarized light cues, provided they have access to the vertically aligned band of maximum polarization near the horizon and a view of landmarks. Once the stars appear in the sky, the birds then recalibrate the star compass with respect of the recalibrated magnetic compass. If sunrise and sunset information can be viewed from the same location, the birds average the information to get a true geographic reference. If polarized light information is not available near the horizon at sunrise or sunset, the birds temporarily transfer the previously calibrated magnetic compass information to the available celestial compasses. We conclude that the type of cue-conflict manipulation and the availability of stars can explain the discrepancies between studies.

A New View on an Old Debate: Type of Cue-Conflict Manipulation and Availability of Stars Can Explain the Discrepancies between Cue-Calibration Experiments with Migratory Songbirds

PubMed Central

Sjöberg, Sissel; Muheim, Rachel

2016-01-01

Migratory birds use multiple compass systems for orientation, including a magnetic, star and sun/polarized light compass. To keep these compasses in register, birds have to regularly update them with respect to a common reference. However, cue-conflict studies have revealed contradictory results on the compass hierarchy, favoring either celestial or magnetic compass cues as the primary calibration reference. Both the geomagnetic field and polarized light cues present at sunrise and sunset have been shown to play a role in compass cue integration, and evidence suggests that polarized light cues at sunrise and sunset may provide the primary calibration reference for the other compass systems. We tested whether migratory garden warblers recalibrated their compasses when they were exposed to the natural celestial cues at sunset in a shifted magnetic field, which are conditions that have been shown to be necessary for the use of a compass reference based on polarized light cues. We released the birds on the same evening under a starry sky and followed them by radio tracking. We found no evidence of compass recalibration, even though the birds had a full view of polarized light cues near the horizon at sunset during the cue-conflict exposure. Based on a meta-analysis of the available literature, we propose an extended unifying theory on compass cue hierarchy used by migratory birds to calibrate the different compasses. According to this scheme, birds recalibrate their magnetic compass by sunrise/sunset polarized light cues, provided they have access to the vertically aligned band of maximum polarization near the horizon and a view of landmarks. Once the stars appear in the sky, the birds then recalibrate the star compass with respect of the recalibrated magnetic compass. If sunrise and sunset information can be viewed from the same location, the birds average the information to get a true geographic reference. If polarized light information is not available near the horizon at sunrise or sunset, the birds temporarily transfer the previously calibrated magnetic compass information to the available celestial compasses. We conclude that the type of cue-conflict manipulation and the availability of stars can explain the discrepancies between studies. PMID:26941631

Catalog of earthquake hypocenters at Alaskan volcanoes: January 1 through December 31, 2002

USGS Publications Warehouse

Dixon, James P.; Stihler, Scott D.; Power, John A.; Tytgat, Guy; Moran, Seth C.; Sánchez, John; Estes, Steve; McNutt, Stephen R.; Paskievitch, John

2003-01-01

The Alaska Volcano Observatory (AVO), a cooperative program of the U.S. Geological Survey, the Geophysical Institute of the University of Alaska Fairbanks, and the Alaska Division of Geological and Geophysical Surveys, has maintained seismic monitoring networks at historically active volcanoes in Alaska since 1988 (Power and others, 1993; Jolly and others, 1996; Jolly and others, 2001; Dixon and others, 2002). The primary objectives of this program are the seismic monitoring of active, potentially hazardous, Alaskan volcanoes and the investigation of seismic processes associated with active volcanism. This catalog presents the basic seismic data and changes in the seismic monitoring program for the period January 1, 2002 through December 31, 2002. Appendix G contains a list of publications pertaining to seismicity of Alaskan volcanoes based on these and previously recorded data. The AVO seismic network was used to monitor twenty-four volcanoes in real time in 2002. These include Mount Wrangell, Mount Spurr, Redoubt Volcano, Iliamna Volcano, Augustine Volcano, Katmai Volcanic Group (Snowy Mountain, Mount Griggs, Mount Katmai, Novarupta, Trident Volcano, Mount Mageik, Mount Martin), Aniakchak Crater, Mount Veniaminof, Pavlof Volcano, Mount Dutton, Isanotski Peaks, Shishaldin Volcano, Fisher Caldera, Westdahl Peak, Akutan Peak, Makushin Volcano, Great Sitkin Volcano, and Kanaga Volcano (Figure 1). Monitoring highlights in 2002 include an earthquake swarm at Great Sitkin Volcano in May-June; an earthquake swarm near Snowy Mountain in July-September; low frequency (1-3 Hz) tremor and long-period events at Mount Veniaminof in September-October and in December; and continuing volcanogenic seismic swarms at Shishaldin Volcano throughout the year. Instrumentation and data acquisition highlights in 2002 were the installation of a subnetwork on Okmok Volcano, the establishment of telemetry for the Mount Veniaminof subnetwork, and the change in the data acquisition system to an EARTHWORM detection system. AVO located 7430 earthquakes during 2002 in the vicinity of the monitored volcanoes. This catalog includes: (1) a description of instruments deployed in the field and their locations; (2) a description of earthquake detection, recording, analysis, and data archival systems; (3) a description of velocity models used for earthquake locations; (4) a summary of earthquakes located in 2002; and (5) an accompanying UNIX tar-file with a summary of earthquake origin times, hypocenters, magnitudes, and location quality statistics; daily station usage statistics; and all HYPOELLIPSE files used to determine the earthquake locations in 2002.The AVO seismic network was used to monitor twenty-four volcanoes in real time in 2002. These include Mount Wrangell, Mount Spurr, Redoubt Volcano, Iliamna Volcano, Augustine Volcano, Katmai Volcanic Group (Snowy Mountain, Mount Griggs, Mount Katmai, Novarupta, Trident Volcano, Mount Mageik, Mount Martin), Aniakchak Crater, Mount Veniaminof, Pavlof Volcano, Mount Dutton, Isanotski Peaks, Shishaldin Volcano, Fisher Caldera, Westdahl Peak, Akutan Peak, Makushin Volcano, Great Sitkin Volcano, and Kanaga Volcano (Figure 1). Monitoring highlights in 2002 include an earthquake swarm at Great Sitkin Volcano in May-June; an earthquake swarm near Snowy Mountain in July-September; low frequency (1-3 Hz) tremor and long-period events at Mount Veniaminof in September-October and in December; and continuing volcanogenic seismic swarms at Shishaldin Volcano throughout the year. Instrumentation and data acquisition highlights in 2002 were the installation of a subnetwork on Okmok Volcano, the establishment of telemetry for the Mount Veniaminof subnetwork, and the change in the data acquisition system to an EARTHWORM detection system. AVO located 7430 earthquakes during 2002 in the vicinity of the monitored volcanoes.This catalog includes: (1) a description of instruments deployed in the field and their locations; (2) a description of earthquake detection, recording, analysis, and data archival systems; (3) a description of velocity models used for earthquake locations; (4) a summary of earthquakes located in 2002; and (5) an accompanying UNIX tar-file with a summary of earthquake origin times, hypocenters, magnitudes, and location quality statistics; daily station usage statistics; and all HYPOELLIPSE files used to determine the earthquake locations in 2002.

Determining the relative contribution of retinal disparity and blur cues to ocular accommodation in Down syndrome.

PubMed

Doyle, Lesley; Saunders, Kathryn J; Little, Julie-Anne

2017-01-10

Individuals with Down syndrome (DS) often exhibit hypoaccommodation alongside accurate vergence. This study investigates the sensitivity of the two systems to retinal disparity and blur cues, establishing the relationship between the two in terms of accommodative-convergence to accommodation (AC/A) and convergence-accommodation to convergence (CA/C) ratios. An objective photorefraction system measured accommodation and vergence under binocular conditions and when retinal disparity and blur cues were removed. Participants were aged 6-16 years (DS n = 41, controls n = 76). Measures were obtained from 65.9% of participants with DS and 100% of controls. Accommodative and vergence responses were reduced with the removal of one or both cues in controls (p < 0.007). For participants with DS, removal of blur was less detrimental to accommodative responses than removal of disparity; accommodative responses being significantly better when all cues were available or when blur was removed in comparison to when proximity was the only available cue. AC/A ratios were larger and CA/C ratios smaller in participants with DS (p < 0.00001). This study demonstrates that retinal disparity is the main driver to both systems in DS and illustrates the diminished influence of retinal blur. High AC/A and low CA/C ratios in combination with disparity-driven responses suggest prioritisation of vergence over accurate accommodation.

Determining the relative contribution of retinal disparity and blur cues to ocular accommodation in Down syndrome

PubMed Central

Doyle, Lesley; Saunders, Kathryn J.; Little, Julie-Anne

2017-01-01

Individuals with Down syndrome (DS) often exhibit hypoaccommodation alongside accurate vergence. This study investigates the sensitivity of the two systems to retinal disparity and blur cues, establishing the relationship between the two in terms of accommodative-convergence to accommodation (AC/A) and convergence-accommodation to convergence (CA/C) ratios. An objective photorefraction system measured accommodation and vergence under binocular conditions and when retinal disparity and blur cues were removed. Participants were aged 6–16 years (DS n = 41, controls n = 76). Measures were obtained from 65.9% of participants with DS and 100% of controls. Accommodative and vergence responses were reduced with the removal of one or both cues in controls (p < 0.007). For participants with DS, removal of blur was less detrimental to accommodative responses than removal of disparity; accommodative responses being significantly better when all cues were available or when blur was removed in comparison to when proximity was the only available cue. AC/A ratios were larger and CA/C ratios smaller in participants with DS (p < 0.00001). This study demonstrates that retinal disparity is the main driver to both systems in DS and illustrates the diminished influence of retinal blur. High AC/A and low CA/C ratios in combination with disparity-driven responses suggest prioritisation of vergence over accurate accommodation. PMID:28071728

SIRTF primary mirror design, analysis, and testing

NASA Technical Reports Server (NTRS)

Sarver, George L., III; Maa, Scott; Chang, LI

1990-01-01

The primary mirror assembly (PMA) requirements and concepts for the Space Infrared Telescope Facility (SIRTF) program are discussed. The PMA studies at NASA/ARC resulted in the design of two engineering test articles, the development of a mirror mount cryogenic static load testing system, and the procurement and partial testing of a full scale spherical mirror mounting system. Preliminary analysis and testing of the single arch mirror with conical mount design and the structured mirror with the spherical mount design indicate that the designs will meet all figure and environmental requirements of the SIRTF program.

Model mount system for testing flutter

NASA Technical Reports Server (NTRS)

Farmer, M. G. (Inventor)

1984-01-01

A wind tunnel model mount system is disclosed for effectively and accurately determining the effects of attack and airstream velocity on a model airfoil or aircraft. The model mount system includes a rigid model attached to a splitter plate which is supported away from the wind tunnel wall several of flexible rods. Conventional instrumentation is employed to effect model rotation through a turntable and to record model flutter data as a function of the angle of attack versus dynamic pressure.

A simple model for studying rotation errors of gimbal mount axes in laser tracking system based on spherical mirror as a reflection unit

NASA Astrophysics Data System (ADS)

Song, Huixu; Shi, Zhaoyao; Chen, Hongfang; Sun, Yanqiang

2018-01-01

This paper presents a novel experimental approach and a simple model for verifying that spherical mirror of laser tracking system could lessen the effect of rotation errors of gimbal mount axes based on relative motion thinking. Enough material and evidence are provided to support that this simple model could replace complex optical system in laser tracking system. This experimental approach and model interchange the kinematic relationship between spherical mirror and gimbal mount axes in laser tracking system. Being fixed stably, gimbal mount axes' rotation error motions are replaced by spatial micro-displacements of spherical mirror. These motions are simulated by driving spherical mirror along the optical axis and vertical direction with the use of precision positioning platform. The effect on the laser ranging measurement accuracy of displacement caused by the rotation errors of gimbal mount axes could be recorded according to the outcome of laser interferometer. The experimental results show that laser ranging measurement error caused by the rotation errors is less than 0.1 μm if radial error motion and axial error motion are under 10 μm. The method based on relative motion thinking not only simplifies the experimental procedure but also achieves that spherical mirror owns the ability to reduce the effect of rotation errors of gimbal mount axes in laser tracking system.

Effect of Cues to Increase Sound Pressure Level on Respiratory Kinematic Patterns during Connected Speech

ERIC Educational Resources Information Center

Huber, Jessica E.

2007-01-01

Purpose: This study examined the response of the respiratory system to 3 cues used to elicit increased vocal loudness to determine whether the effects of cueing, shown previously in sentence tasks, were present in connected speech tasks and to describe differences among tasks. Method: Fifteen young men and 15 young women produced a 2-paragraph…

The role of the sun in the celestial compass of dung beetles

PubMed Central

Dacke, M.; el Jundi, Basil; Smolka, Jochen; Byrne, Marcus; Baird, Emily

2014-01-01

Recent research has focused on the different types of compass cues available to ball-rolling beetles for orientation, but little is known about the relative precision of each of these cues and how they interact. In this study, we find that the absolute orientation error of the celestial compass of the day-active dung beetle Scarabaeus lamarcki doubles from 16° at solar elevations below 60° to an error of 29° at solar elevations above 75°. As ball-rolling dung beetles rely solely on celestial compass cues for their orientation, these insects experience a large decrease in orientation precision towards the middle of the day. We also find that in the compass system of dung beetles, the solar cues and the skylight cues are used together and share the control of orientation behaviour. Finally, we demonstrate that the relative influence of the azimuthal position of the sun for straight-line orientation decreases as the sun draws closer to the horizon. In conclusion, ball-rolling dung beetles possess a dynamic celestial compass system in which the orientation precision and the relative influence of the solar compass cues change over the course of the day. PMID:24395963

The role of the sun in the celestial compass of dung beetles.

PubMed

Dacke, M; el Jundi, Basil; Smolka, Jochen; Byrne, Marcus; Baird, Emily

2014-01-01

Recent research has focused on the different types of compass cues available to ball-rolling beetles for orientation, but little is known about the relative precision of each of these cues and how they interact. In this study, we find that the absolute orientation error of the celestial compass of the day-active dung beetle Scarabaeus lamarcki doubles from 16° at solar elevations below 60° to an error of 29° at solar elevations above 75°. As ball-rolling dung beetles rely solely on celestial compass cues for their orientation, these insects experience a large decrease in orientation precision towards the middle of the day. We also find that in the compass system of dung beetles, the solar cues and the skylight cues are used together and share the control of orientation behaviour. Finally, we demonstrate that the relative influence of the azimuthal position of the sun for straight-line orientation decreases as the sun draws closer to the horizon. In conclusion, ball-rolling dung beetles possess a dynamic celestial compass system in which the orientation precision and the relative influence of the solar compass cues change over the course of the day.

Decision Utility, Incentive Salience, and Cue-Triggered “Wanting”

PubMed Central

Berridge, Kent C.; Aldridge, J. Wayne

2010-01-01

This chapter examines brain mechanisms of reward utility operating at particular decision moments in life—moments such as when one encounters an image, sound, scent, or other cue associated in the past with a particular reward or perhaps just when one vividly imagines that cue. Such a cue can often trigger a sudden motivational urge to pursue its reward and sometimes a decision to do so. Drawing on a utility taxonomy that distinguishes among subtypes of reward utility—predicted utility, decision utility, experienced utility, and remembered utility—it is shown how cue-triggered cravings, such as an addict’s surrender to relapse, can hang on special transformations by brain mesolimbic systems of one utility subtype, namely, decision utility. The chapter focuses on a particular form of decision utility called incentive salience, a type of “wanting” for rewards that is amplified by brain mesolimbic systems. Sudden peaks of intensity of incentive salience, caused by neurobiological mechanisms, can elevate the decision utility of a particular reward at the moment its cue occurs. An understanding of what happens at such moments leads to a better understanding of the mechanisms at work in decision making in general. PMID:25309963

Decision Utility, Incentive Salience, and Cue-Triggered "Wanting"

PubMed

Berridge, Kent C; Aldridge, J Wayne

2009-01-01

This chapter examines brain mechanisms of reward utility operating at particular decision moments in life-moments such as when one encounters an image, sound, scent, or other cue associated in the past with a particular reward or perhaps just when one vividly imagines that cue. Such a cue can often trigger a sudden motivational urge to pursue its reward and sometimes a decision to do so. Drawing on a utility taxonomy that distinguishes among subtypes of reward utility-predicted utility, decision utility, experienced utility, and remembered utility-it is shown how cue-triggered cravings, such as an addict's surrender to relapse, can hang on special transformations by brain mesolimbic systems of one utility subtype, namely, decision utility. The chapter focuses on a particular form of decision utility called incentive salience, a type of "wanting" for rewards that is amplified by brain mesolimbic systems. Sudden peaks of intensity of incentive salience, caused by neurobiological mechanisms, can elevate the decision utility of a particular reward at the moment its cue occurs. An understanding of what happens at such moments leads to a better understanding of the mechanisms at work in decision making in general.

Dynamics and control simulation of the Spacelab Experiment Pointing Mount

NASA Technical Reports Server (NTRS)

Marsh, E. L.; Ward, R. S.

1977-01-01

Computer simulations were developed to evaluate the performance of four Experiment Pointing Mounts (EPM) being considered for Spacelab experiments in the 1980-1990 time frame. The system modeled compromises a multibody system consisting of the shuttle, a mechanical isolation device, the EPM, celestial and inertial sensors, bearings, gimbal torque motors and associated nonlinearities, the experiment payload, and control and estimator algorithms. Each mount was subjected to a common disturbance (shuttle vernier thruster firing and man push off) and command (stellar pointing or solar raster scan) input. The fundamental limitation common to all mounts was found to be sensor noise. System dynamics and hardware nonlinearities have secondary effects on pointing performance for sufficiently high bandwidth.

Exposure to retrieval cues improves retention performance and induces changes in ACTH and corticosterone release.

PubMed

Gisquet-Verrier, Pascale; Botreau, Fanny; Venero, Cesar; Sandi, Carmen

2004-05-01

Memory retrieval can be facilitated by pretest exposure to cues associated with the original training. The present series of experiments was aimed at investigating whether the effectiveness of the retrieval cues might be due to their emotional value and thus be associated to a particular pattern of activation of stress systems. Therefore, the effects of exposing rats to different cueing conditions were investigated both on retention performance and on the level of different stress hormones (ACTH, corticosterone and glucose; the latter as an indirect index of adrenergic/sympathetic nervous system activation). Rats trained in a brightness avoidance discrimination task exhibited an enhancement of the retention performance following exposure to the light discriminative stimulus when delivered 1-day after training and not after 21 days, while exposure to contextual cues led to opposite effects on the retention performance, confirming our previous results. Analyses of the level of stress hormones at the time of testing indicated that when the retrieval cues were effective at the behavioral level, cued rats exhibited higher ACTH plasmatic levels than controls, but did not differ in their glucose or corticosterone levels. Further experiments showed that one day after training, both ACTH and corticosterone levels were elevated in light-cued rats if hormone samples were taken 15 min after cueing. These results show that exposure to an effective retrieval cue is accompanied by the activation of the hypothalamus-pituitary-adrenal axis. The possible involvement of the Corticotropin Releasing Factor at the level of the hypothalamus and amygdala (particularly the central nucleus) on the facilitating effect on retention performance following exposure to aversive training-associated cues is discussed. The present results strengthen the notion that emotion can interact with retrieval processes.

Analysis of engagement behavior in children during dyadic interactions using prosodic cues.

PubMed

Gupta, Rahul; Bone, Daniel; Lee, Sungbok; Narayanan, Shrikanth

2016-05-01

Child engagement is defined as the interaction of a child with his/her environment in a contextually appropriate manner. Engagement behavior in children is linked to socio-emotional and cognitive state assessment with enhanced engagement identified with improved skills. A vast majority of studies however rely solely, and often implicitly, on subjective perceptual measures of engagement. Access to automatic quantification could assist researchers/clinicians to objectively interpret engagement with respect to a target behavior or condition, and furthermore inform mechanisms for improving engagement in various settings. In this paper, we present an engagement prediction system based exclusively on vocal cues observed during structured interaction between a child and a psychologist involving several tasks. Specifically, we derive prosodic cues that capture engagement levels across the various tasks. Our experiments suggest that a child's engagement is reflected not only in the vocalizations, but also in the speech of the interacting psychologist. Moreover, we show that prosodic cues are informative of the engagement phenomena not only as characterized over the entire task (i.e., global cues), but also in short term patterns (i.e., local cues). We perform a classification experiment assigning the engagement of a child into three discrete levels achieving an unweighted average recall of 55.8% (chance is 33.3%). While the systems using global cues and local level cues are each statistically significant in predicting engagement, we obtain the best results after fusing these two components. We perform further analysis of the cues at local and global levels to achieve insights linking specific prosodic patterns to the engagement phenomenon. We observe that while the performance of our model varies with task setting and interacting psychologist, there exist universal prosodic patterns reflective of engagement.

Two-Degree-of-Freedom Mount System for Flutter Models

NASA Technical Reports Server (NTRS)

Farmer, M. G.

1983-01-01

Flexible rods replace conventional bearing supports to minimize structural damping. Aerodynamic damping not masked by effects of mount system, making more accurate studies possible of how aerodynamic damping varies as flow over model changed. New system called PAPA.

The language used in describing autobiographical memories prompted by life period visually presented verbal cues, event-specific visually presented verbal cues and short musical clips of popular music.

PubMed

Zator, Krysten; Katz, Albert N

2017-07-01

Here, we examined linguistic differences in the reports of memories produced by three cueing methods. Two groups of young adults were cued visually either by words representing events or popular cultural phenomena that took place when they were 5, 10, or 16 years of age, or by words referencing a general lifetime period word cue directing them to that period in their life. A third group heard 30-second long musical clips of songs popular during the same three time periods. In each condition, participants typed a specific event memory evoked by the cue and these typed memories were subjected to analysis by the Linguistic Inquiry and Word Count (LIWC) program. Differences in the reports produced indicated that listening to music evoked memories embodied in motor-perceptual systems more so than memories evoked by our word-cueing conditions. Additionally, relative to music cues, lifetime period word cues produced memories with reliably more uses of personal pronouns, past tense terms, and negative emotions. The findings provide evidence for the embodiment of autobiographical memories, and how those differ when the cues emphasise different aspects of the encoded events.

77 FR 61401 - Notice of Availability of Government-Owned Inventions; Available for Licensing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

... FOR UNMANNED UNDERSEA VEHICLES//Patent No. 7,721,666: HULL-MOUNTED LINE RETRIEVAL AND RELEASE SYSTEM... EXTERNALLY MOUNTED SLEWING CRANE FOR SHIPPING CONTAINERS// Patent No. 7,730,843: HULL-MOUNTED LINE RETRIEVAL...

Maternal Olfactory Cues Synchronize the Circadian System of Artificially Raised Newborn Rabbits

PubMed Central

Montúfar-Chaveznava, Rodrigo; Trejo-Muñoz, Lucero; Hernández-Campos, Oscar; Navarrete, Erika; Caldelas, Ivette

2013-01-01

In European newborn rabbits, once-daily nursing acts as a strong non-photic entraining cue for the pre-visual circadian system. Nevertheless, there is a lack of information regarding which of the non-photic cues are capable of modulating pup circadian system. In this study, for the first time, we determined that the mammary pheromone 2-methylbut-2-enal (2MB2) presented in the maternal milk acts as a non-photic entraining cue. We evaluated the effect of once-daily exposure to maternal olfactory cues on the temporal pattern of core body temperature, gross locomotor activity and metabolic variables (liver weight, serum glucose, triacylglycerides, free fatty acids, cholecystokinin and cholesterol levels) in newborn rabbits. Rabbit pups were separated from their mothers from postnatal day 1 (P1) to P8 and were randomly assigned to one of the following conditions: nursed by a lactating doe (NAT); exposed to a 3-min pulse of maternal milk (M-Milk), mammary pheromone (2MB2), or water (H2O). To eliminate maternal stimulation, the pups of the last three groups were artificially fed once every 24-h. On P8, the rabbits were sacrificed at different times of the day. In temperature and activity, the NAT, M-Milk and 2MB2 groups exhibited clear diurnal rhythmicity with a conspicuous anticipatory rise hours prior to nursing. In contrast, the H2O group exhibited atypical rhythmicity in both parameters, lacking the anticipatory component. At the metabolic level, all of the groups exhibited a diurnal pattern with similar phases in liver weight and metabolites examined. The results obtained in this study suggest that during pre-visual stages of development, the circadian system of newborn rabbits is sensitive to the maternal olfactory cues contained in milk, indicating that these cues function as non-photic entraining signals mainly for the central oscillators regulating the expression of temperature and behavior, whereas in metabolic diurnal rhythmicity, these cues lack an effect, indicating that peripheral oscillators respond to milk administration. PMID:24040161

Launch Lock Assemblies Including Axial Gap Amplification Devices and Spacecraft Isolation Systems Including the Same

NASA Technical Reports Server (NTRS)

Barber, Tim Daniel (Inventor); Hindle, Timothy (Inventor); Young, Ken (Inventor); Davis, Torey (Inventor)

2014-01-01

Embodiments of a launch lock assembly are provided, as are embodiments of a spacecraft isolation system including one or more launch lock assemblies. In one embodiment, the launch lock assembly includes first and second mount pieces, a releasable clamp device, and an axial gap amplification device. The releasable clamp device normally maintains the first and second mount pieces in clamped engagement; and, when actuated, releases the first and second mount pieces from clamped engagement to allow relative axial motion there between. The axial gap amplification device normally residing in a blocking position wherein the gap amplification device obstructs relative axial motion between the first and second mount pieces. The axial gap amplification device moves into a non-blocking position when the first and second mount pieces are released from clamped engagement to increase the range of axial motion between the first and second mount pieces.

Nonlinear Motion Cueing Algorithm: Filtering at Pilot Station and Development of the Nonlinear Optimal Filters for Pitch and Roll

NASA Technical Reports Server (NTRS)

Zaychik, Kirill B.; Cardullo, Frank M.

2012-01-01

Telban and Cardullo have developed and successfully implemented the non-linear optimal motion cueing algorithm at the Visual Motion Simulator (VMS) at the NASA Langley Research Center in 2005. The latest version of the non-linear algorithm performed filtering of motion cues in all degrees-of-freedom except for pitch and roll. This manuscript describes the development and implementation of the non-linear optimal motion cueing algorithm for the pitch and roll degrees of freedom. Presented results indicate improved cues in the specified channels as compared to the original design. To further advance motion cueing in general, this manuscript describes modifications to the existing algorithm, which allow for filtering at the location of the pilot's head as opposed to the centroid of the motion platform. The rational for such modification to the cueing algorithms is that the location of the pilot's vestibular system must be taken into account as opposed to the off-set of the centroid of the cockpit relative to the center of rotation alone. Results provided in this report suggest improved performance of the motion cueing algorithm.

Power System Implementation and Demonstration at Camp Katuu, Palau

DTIC Science & Technology

2011-05-11

Horizontal Rows 3 Vertical Rows 3 Vertical Rows with Center Walkway 6 Vertical Rows 1 Amount of rail mounting (lf) 1440’ 1800’ 1800’ 1440’ 2 Ease of rail...installation some rail cutting required to clear walkway requires two level rail mounting system requires two level rail mounting system no rail...Maintenance access 21" horizontal & vertical walkway , does not have direct access to all panels Accessible with 15" walkways Direct access to each panel and

Reversal of alcohol dependence-induced deficits in cue-guided behavior via mGluR2/3 signaling in mice.

PubMed

Barker, Jacqueline M; Lench, Daniel H; Chandler, L Judson

2016-01-01

Alcohol use disorders are associated with deficits in adaptive behavior. While some behavioral impairments that are associated with alcohol use disorders may predate exposure to drugs of abuse, others may result directly from exposure to drugs of abuse, including alcohol. Identifying a causal role for how alcohol exposure leads to these impairments will enable further investigation of the neurobiological mechanisms by which it acts to dysregulate adaptive behavior. In the present study, we examined the effects of chronic intermittent ethanol exposure (CIE) on the use of reward-paired cues to guide consummatory behaviors in a mouse model, and further, how manipulations of mGluR2/3 signaling-known to be dysregulated after chronic alcohol exposure-may alter the expression of this behavior. Adult male C57B/6J mice were trained to self-administer 10 % ethanol and exposed to CIE via vapor inhalation. After CIE exposure, mice were trained in a Pavlovian task wherein a cue (tone) was paired with the delivery of a 10 % sucrose unconditioned stimulus. The use of the reward-paired cue to guide licking behavior was determined across training. The effect of systemic mGluR2/3 manipulation on discrimination between cue-on and cue-off intervals was assessed by administration of the mGluR2/3 agonist LY379268 or the antagonist LY341495 prior to a testing session. Exposure to CIE resulted in reductions in discrimination between cue-on and cue-off intervals, with CIE-exposed mice exhibiting significantly lower consummatory behavior during reward-paired cues than air controls. In addition, systemic administration of an mGluR2/3 agonist restored the use of reward-paired cues in CIE-exposed animals without impacting behavior in air controls. Conversely, administration of an mGluR2/3 antagonist mimicked the effects of CIE on cue-guided licking behavior, indicating that mGluR2/3 signaling can bidirectionally regulate the ability to use reward-paired cues to guide behavior. Together, these data suggest that chronic ethanol exposure drives impairments in the ability to use reward-paired cues to adaptively regulate behavior and that mGluR2/3 receptors represent a therapeutic target for restoration of these deficits in behavioral control in the alcoholic.

Support System for Solar Receivers

NASA Technical Reports Server (NTRS)

Kiceniuk, T.

1985-01-01

Hinged split-ring mounts insure safe support of heavy receivers. In addition to safer operation and damage-free mounting system provides more accurate focusing, and small incremental adjustments of ring more easily made.

Sensorimotor Adaptation Following Exposure to Ambiguous Inertial Motion Cues

NASA Technical Reports Server (NTRS)

Wood, S. J.; Clement, G. R.; Rupert, A. H.; Reschke, M. F.; Harm, D. L.; Guedry, F. E.

2007-01-01

The central nervous system must resolve the ambiguity of inertial motion sensory cues in order to derive accurate spatial orientation awareness. Adaptive changes in how inertial cues from the otolith system are integrated with other sensory information lead to perceptual and postural disturbances upon return to Earth s gravity. The primary goals of this ground-based research investigation are to explore physiological mechanisms and operational implications of tilt-translation disturbances during and following re-entry, and to evaluate a tactile prosthesis as a countermeasure for improving control of whole-body orientation during tilt and translation motion.

Lightweight helmet-mounted eye movement measurement system

NASA Technical Reports Server (NTRS)

Barnes, J. A.

1978-01-01

The helmet-mounted eye movement measuring system, weighs 1,530 grams; the weight of the present aviators' helmet in standard form with the visor is 1,545 grams. The optical head is standard NAC Eye-Mark. This optical head was mounted on a magnesium yoke which in turn was attached to a slide cam mounted on the flight helmet. The slide cam allows one to adjust the eye-to-optics system distance quite easily and to secure it so that the system will remain in calibration. The design of the yoke and slide cam is such that the subject can, in an emergency, move the optical head forward and upward to the stowed and locked position atop the helmet. This feature was necessary for flight safety. The television camera that is used in the system is a solid state General Electric TN-2000 with a charged induced device imager used as the vidicon.

Distinct heat shock factors and chromatin modifications mediate the organ-autonomous transcriptional memory of heat stress.

PubMed

Liu, Hsiang-Chin; Lämke, Jörn; Lin, Siou-Ying; Hung, Meng-Ju; Liu, Kuan-Ming; Charng, Yee-Yung; Bäurle, Isabel

2018-05-11

Plants can be primed by a stress cue to mount a faster or stronger activation of defense mechanisms upon a subsequent stress. A crucial component of such stress priming is the modified reactivation of genes upon recurring stress; however, the underlying mechanisms are poorly understood. Here, we report that dozens of Arabidopsis thaliana genes display transcriptional memory, i.e. stronger upregulation after a recurring heat stress, that lasts for at least three days. We define a set of transcription factors involved in this memory response and show that the transcriptional memory results in enhanced transcriptional activation within minutes after the onset of a heat stress cue. Further, we show that the transcriptional memory is active in all tissues. It may last for up to a week, and is associated with histone H3 lysine 4 hyper-methylation during this time. This transcriptional memory is cis-encoded, as we identify a promoter fragment that confers memory onto a heterologous gene. In summary, heat-induced transcriptional memory is a widespread and sustained response, and our study provides a framework for future mechanistic studies of somatic stress memory in higher plants. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Role of somatosensory and vestibular cues in attenuating visually induced human postural sway

NASA Technical Reports Server (NTRS)

Peterka, R. J.; Benolken, M. S.

1995-01-01

The purpose of this study was to determine the contribution of visual, vestibular, and somatosensory cues to the maintenance of stance in humans. Postural sway was induced by full-field, sinusoidal visual surround rotations about an axis at the level of the ankle joints. The influences of vestibular and somatosensory cues were characterized by comparing postural sway in normal and bilateral vestibular absent subjects in conditions that provided either accurate or inaccurate somatosensory orientation information. In normal subjects, the amplitude of visually induced sway reached a saturation level as stimulus amplitude increased. The saturation amplitude decreased with increasing stimulus frequency. No saturation phenomena were observed in subjects with vestibular loss, implying that vestibular cues were responsible for the saturation phenomenon. For visually induced sways below the saturation level, the stimulus-response curves for both normal subjects and subjects experiencing vestibular loss were nearly identical, implying (1) that normal subjects were not using vestibular information to attenuate their visually induced sway, possibly because sway was below a vestibular-related threshold level, and (2) that subjects with vestibular loss did not utilize visual cues to a greater extent than normal subjects; that is, a fundamental change in visual system "gain" was not used to compensate for a vestibular deficit. An unexpected finding was that the amplitude of body sway induced by visual surround motion could be almost 3 times greater than the amplitude of the visual stimulus in normal subjects and subjects with vestibular loss. This occurred in conditions where somatosensory cues were inaccurate and at low stimulus amplitudes. A control system model of visually induced postural sway was developed to explain this finding. For both subject groups, the amplitude of visually induced sway was smaller by a factor of about 4 in tests where somatosensory cues provided accurate versus inaccurate orientation information. This implied (1) that the subjects experiencing vestibular loss did not utilize somatosensory cues to a greater extent than normal subjects; that is, changes in somatosensory system "gain" were not used to compensate for a vestibular deficit, and (2) that the threshold for the use of vestibular cues in normal subjects was apparently lower in test conditions where somatosensory cues were providing accurate orientation information.

Sensory Flask Cells in Sponge Larvae Regulate Metamorphosis via Calcium Signaling.

PubMed

Nakanishi, Nagayasu; Stoupin, Daniel; Degnan, Sandie M; Degnan, Bernard M

2015-12-01

The Porifera (sponges) is one of the earliest phyletic lineages to branch off the metazoan tree. Although the body-plan of sponges is among the simplest in the animal kingdom and sponges lack nervous systems that communicate environmental signals to other cells, their larvae have sensory systems that generate coordinated responses to environmental cues. In eumetazoans (Cnidaria and Bilateria), the nervous systems of larvae often regulate metamorphosis through Ca(2+)-dependent signal transduction. In sponges, neither the identity of the receptor system that detects an inductive environmental cue (hereafter "metamorphic cues") nor the signaling system that mediates settlement and metamorphosis are known. Using a combination of behavioral assays and surgical manipulations, we show here that specialized epithelial cells-referred to as flask cells-enriched in the anterior third of the Amphimedon queenslandica larva are most likely to be the sensory cells that detect the metamorphic cues. Surgical removal of the region enriched in flask cells in a larva inhibits the initiation of metamorphosis. The flask cell has an apical sensory apparatus with a cilium surrounded by an apical F-actin-rich protrusion, and numerous vesicles, hallmarks of eumetazoan sensory-neurosecretory cells. We demonstrate that these flask cells respond to metamorphic cues by elevating intracellular Ca(2+) levels, and that this elevation is necessary for the initiation of metamorphosis. Taken together, these analyses suggest that sponge larvae have sensory-secretory epithelial cells capable of converting exogenous cues into internal signals via Ca(2+)-mediated signaling, which is necessary for the initiation of metamorphosis. Similarities in the morphology, physiology, and function of the sensory flask cells in sponge larvae with the sensory/neurosecretory cells in eumetazoan larvae suggest this sensory system predates the divergence of Porifera and Eumetazoa. © The Author 2015. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email: journals.permissions@oup.com.

Top-down controlled alpha band activity in somatosensory areas determines behavioral performance in a discrimination task.

PubMed

Haegens, Saskia; Händel, Barbara F; Jensen, Ole

2011-04-06

The brain receives a rich flow of information which must be processed according to behavioral relevance. How is the state of the sensory system adjusted to up- or downregulate processing according to anticipation? We used magnetoencephalography to investigate whether prestimulus alpha band activity (8-14 Hz) reflects allocation of attentional resources in the human somatosensory system. Subjects performed a tactile discrimination task where a visual cue directed attention to their right or left hand. The strength of attentional modulation was controlled by varying the reliability of the cue in three experimental blocks (100%, 75%, or 50% valid cueing). While somatosensory prestimulus alpha power lateralized strongly with a fully predictive cue (100%), lateralization was decreased with lower cue reliability (75%) and virtually absent if the cue had no predictive value at all (50%). Importantly, alpha lateralization influenced the subjects' behavioral performance positively: both accuracy and speed of response improved with the degree of alpha lateralization. This study demonstrates that prestimulus alpha lateralization in the somatosensory system behaves similarly to posterior alpha activity observed in visual attention tasks. Our findings extend the notion that alpha band activity is involved in shaping the functional architecture of the working brain by determining both the engagement and disengagement of specific regions: the degree of anticipation modulates the alpha activity in sensory regions in a graded manner. Thus, the alpha activity is under top-down control and seems to play an important role for setting the state of sensory regions to optimize processing.

Social cognitive conflict resolution: Contributions of domain general and domain specific neural systems

PubMed Central

Zaki, Jamil; Hennigan, Kelly; Weber, Jochen; Ochsner, Kevin N.

2010-01-01

Cognitive control mechanisms allow individuals to behave adaptively in the face of complex and sometimes conflicting information. While the neural bases of these control mechanisms have been examined in many contexts, almost no attention has been paid to their role in resolving conflicts between competing social cues, which is surprising, given that cognitive conflicts are part of many social interactions. Evidence about the neural processing of social information suggests that two systems—the mirror neuron system (MNS) and mental state attribution system (MSAS)—are specialized for processing nonverbal and contextual social cues, respectively. This could support a model of social cognitive conflict resolution in which competition between social cues would recruit domain-general cognitive control mechanisms, which in turn would bias processing towards the MNS or MSAS. Such biasing could also alter social behaviors, such as inferences made about the internal states of others. We tested this model by scanning participants using fMRI while they drew inferences about social targets' emotional states based on congruent or incongruent nonverbal and contextual social cues. Conflicts between social cues recruited the anterior cingulate and lateral prefrontal cortex, brain areas associated with domain-general control processes. This activation was accompanied by biasing of neural activity towards areas in the MNS or MSAS, which tracked, respectively, with perceivers' behavioral reliance on nonverbal or contextual cues when drawing inferences about targets' emotions. Together, these data provide evidence about both domain general and domain specific mechanisms involved in resolving social cognitive conflicts. PMID:20573895

Research on Measurement Accuracy of Laser Tracking System Based on Spherical Mirror with Rotation Errors of Gimbal Mount Axes

NASA Astrophysics Data System (ADS)

Shi, Zhaoyao; Song, Huixu; Chen, Hongfang; Sun, Yanqiang

2018-02-01

This paper presents a novel experimental approach for confirming that spherical mirror of a laser tracking system can reduce the influences of rotation errors of gimbal mount axes on the measurement accuracy. By simplifying the optical system model of laser tracking system based on spherical mirror, we can easily extract the laser ranging measurement error caused by rotation errors of gimbal mount axes with the positions of spherical mirror, biconvex lens, cat's eye reflector, and measuring beam. The motions of polarization beam splitter and biconvex lens along the optical axis and vertical direction of optical axis are driven by error motions of gimbal mount axes. In order to simplify the experimental process, the motion of biconvex lens is substituted by the motion of spherical mirror according to the principle of relative motion. The laser ranging measurement error caused by the rotation errors of gimbal mount axes could be recorded in the readings of laser interferometer. The experimental results showed that the laser ranging measurement error caused by rotation errors was less than 0.1 μm if radial error motion and axial error motion were within ±10 μm. The experimental method simplified the experimental procedure and the spherical mirror could reduce the influences of rotation errors of gimbal mount axes on the measurement accuracy of the laser tracking system.

Mount mechanisms for the Saturn 5/Apollo mobile launcher at John F. Kennedy Space Center

NASA Technical Reports Server (NTRS)

Balke, H. A.

1975-01-01

A support system was designed to resist hurricane wind loads at the launch pad and to allow the supported structural frame to expand and contract freely under wide ranges of temperature. This system consists of six mount mechanisms devised to meet the previously stated requirements plus a load-carrying capacity for each of 3.2-million kilograms (7-million pounds) downward and 1.6-million kilograms (3.5-million pounds) upward. A similar but lighter system of six mount mechanisms was designed for use in the sheltered environment of the vehicle assembly building. Each requirement and design result is discussed, and each mount mechanism is defined by location and type with references to visual presentations.

Raster graphic helmet-mounted display study

NASA Technical Reports Server (NTRS)

Beamon, William S.; Moran, Susanna I.

1990-01-01

A design of a helmet mounted display system is presented, including a design specification and development plan for the selected design approach. The requirements for the helmet mounted display system and a survey of applicable technologies are presented. Three helmet display concepts are then described which utilize lasers, liquid crystal display's (LCD's), and subminiature cathode ray tubes (CRT's), respectively. The laser approach is further developed in a design specification and a development plan.

Gazing at me: the importance of social meaning in understanding direct-gaze cues

PubMed Central

Hamilton, Antonia F. de C.

2016-01-01

Direct gaze is an engaging and important social cue, but the meaning of direct gaze depends heavily on the surrounding context. This paper reviews some recent studies of direct gaze, to understand more about what neural and cognitive systems are engaged by this social cue and why. The data show that gaze can act as an arousal cue and can modulate actions, and can activate brain regions linked to theory of mind and self-related processing. However, all these results are strongly modulated by the social meaning of a gaze cue and by whether participants believe that another person is really watching them. The implications of these contextual effects and audience effects for our theories of gaze are considered. PMID:26644598

Head-mounted active noise control system with virtual sensing technique

NASA Astrophysics Data System (ADS)

Miyazaki, Nobuhiro; Kajikawa, Yoshinobu

2015-03-01

In this paper, we apply a virtual sensing technique to a head-mounted active noise control (ANC) system we have already proposed. The proposed ANC system can reduce narrowband noise while improving the noise reduction ability at the desired locations. A head-mounted ANC system based on an adaptive feedback structure can reduce noise with periodicity or narrowband components. However, since quiet zones are formed only at the locations of error microphones, an adequate noise reduction cannot be achieved at the locations where error microphones cannot be placed such as near the eardrums. A solution to this problem is to apply a virtual sensing technique. A virtual sensing ANC system can achieve higher noise reduction at the desired locations by measuring the system models from physical sensors to virtual sensors, which will be used in the online operation of the virtual sensing ANC algorithm. Hence, we attempt to achieve the maximum noise reduction near the eardrums by applying the virtual sensing technique to the head-mounted ANC system. However, it is impossible to place the microphone near the eardrums. Therefore, the system models from physical sensors to virtual sensors are estimated using the Head And Torso Simulator (HATS) instead of human ears. Some simulation, experimental, and subjective assessment results demonstrate that the head-mounted ANC system with virtual sensing is superior to that without virtual sensing in terms of the noise reduction ability at the desired locations.

Turbomachine blade reinforcement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garcia Crespo, Andres Jose

Embodiments of the present disclosure include a system having a turbomachine blade segment including a blade and a mounting segment coupled to the blade, wherein the mounting segment has a plurality of reinforcement pins laterally extending at least partially through a neck of the mounting segment.

A model for the pilot's use of motion cues in roll-axis tracking tasks

NASA Technical Reports Server (NTRS)

Levison, W. H.; Junker, A. M.

1977-01-01

Simulated target-following and disturbance-regulation tasks were explored with subjects using visual-only and combined visual and motion cues. The effects of motion cues on task performance and pilot response behavior were appreciably different for the two task configurations and were consistent with data reported in earlier studies for similar task configurations. The optimal-control model for pilot/vehicle systems provided a task-independent framework for accounting for the pilot's use of motion cues. Specifically, the availability of motion cues was modeled by augmenting the set of perceptual variables to include position, rate, acceleration, and accleration-rate of the motion simulator, and results were consistent with the hypothesis of attention-sharing between visual and motion variables. This straightforward informational model allowed accurate model predictions of the effects of motion cues on a variety of response measures for both the target-following and disturbance-regulation tasks.

Flat conductor cable commercialization project

NASA Technical Reports Server (NTRS)

Hogarth, P.; Wadsworth, E.

1977-01-01

An undercarpet flat conductor cable and a baseboard flat conductor cable system were studied for commercialization. The undercarpet system is designed for use in office and commercial buildings. It employs a flat power cable, protected by a grounded metal shield, that terminates in receptacles mounted on the floor. It is designed to interface with a flat conductor cable telephone system. The baseboard system consists of a flat power cable mounted in a plastic raceway; both the raceway and the receptacles are mounted on the surface of the baseboard. It is designed primarily for use in residential buildings, particularly for renovation and concrete and masonry construction.

a Man-Portable Imu-Free Mobile Mapping System

NASA Astrophysics Data System (ADS)

Nüchter, A.; Borrmann, D.; Koch, P.; Kühn, M.; May, S.

2015-08-01

Mobile mapping systems are commonly mounted on cars, ships and robots. The data is directly geo-referenced using GPS data and expensive IMU (inertial measurement systems). Driven by the need for flexible, indoor mapping systems we present an inexpensive mobile mapping solution that can be mounted on a backpack. It combines a horizontally mounted 2D profiler with a constantly spinning 3D laser scanner. The initial system featuring a low-cost MEMS IMU was revealed and demonstrated at MoLaS: Technology Workshop Mobile Laser Scanning at Fraunhofer IPM in Freiburg in November 2014. In this paper, we present an IMU-free solution.

Photoelectric panel with equatorial mounting of drive

NASA Astrophysics Data System (ADS)

Kukhta, M. S.; Krauinsh, P. Y.; Krauinsh, D. P.; Sokolov, A. P.; Mainy, S. B.

2018-03-01

The relevance of the work is determined by the need to create effective models for sunny energy. The article considers a photoelectric panel equipped with a system for tracking the sun. Efficiency of the system is provided by equatorial mounting, which compensates for the rotation of the Earth by rotating the sunny panel in the plane of the celestial equator. The specificity of climatic and geographical conditions of Tomsk is estimated. The dynamics of power variations of photoelectric panels with equatorial mounting during seasonal fluctuations in Tomsk is calculated. A mobile photovoltaic panel with equatorial mounting of the drive has been developed. The methods of design strategy for placing photovoltaic panels in the architectural environment of the city are presented. Key words: sunny energy, photovoltaics, equatorial mounting, mechatronic model, wave reducer, electric drive.

Robust cue integration: a Bayesian model and evidence from cue-conflict studies with stereoscopic and figure cues to slant.

PubMed

Knill, David C

2007-05-23

Most research on depth cue integration has focused on stimulus regimes in which stimuli contain the small cue conflicts that one might expect to normally arise from sensory noise. In these regimes, linear models for cue integration provide a good approximation to system performance. This article focuses on situations in which large cue conflicts can naturally occur in stimuli. We describe a Bayesian model for nonlinear cue integration that makes rational inferences about scenes across the entire range of possible cue conflicts. The model derives from the simple intuition that multiple properties of scenes or causal factors give rise to the image information associated with most cues. To make perceptual inferences about one property of a scene, an ideal observer must necessarily take into account the possible contribution of these other factors to the information provided by a cue. In the context of classical depth cues, large cue conflicts most commonly arise when one or another cue is generated by an object or scene that violates the strongest form of constraint that makes the cue informative. For example, when binocularly viewing a slanted trapezoid, the slant interpretation of the figure derived by assuming that the figure is rectangular may conflict greatly with the slant suggested by stereoscopic disparities. An optimal Bayesian estimator incorporates the possibility that different constraints might apply to objects in the world and robustly integrates cues with large conflicts by effectively switching between different internal models of the prior constraints underlying one or both cues. We performed two experiments to test the predictions of the model when applied to estimating surface slant from binocular disparities and the compression cue (the aspect ratio of figures in an image). The apparent weight that subjects gave to the compression cue decreased smoothly as a function of the conflict between the cues but did not shrink to zero; that is, subjects did not fully veto the compression cue at large cue conflicts. A Bayesian model that assumes a mixed prior distribution of figure shapes in the world, with a large proportion being very regular and a smaller proportion having random shapes, provides a good quantitative fit for subjects' performance. The best fitting model parameters are consistent with the sensory noise to be expected in measurements of figure shape, further supporting the Bayesian model as an account of robust cue integration.

Calibration of magnetic and celestial compass cues in migratory birds--a review of cue-conflict experiments.

PubMed

Muheim, Rachel; Moore, Frank R; Phillips, John B

2006-01-01

Migratory birds use multiple sources of compass information for orientation, including the geomagnetic field, the sun, skylight polarization patterns and star patterns. In this paper we review the results of cue-conflict experiments designed to determine the relative importance of the different compass mechanisms, and how directional information from these compass mechanisms is integrated. We focus on cue-conflict experiments in which the magnetic field was shifted in alignment relative to natural celestial cues. Consistent with the conclusions of earlier authors, our analyses suggest that during the premigratory season, celestial information is given the greatest salience and used to recalibrate the magnetic compass by both juvenile and adult birds. Sunset polarized light patterns from the region of the sky near the horizon appear to provide the calibration reference for the magnetic compass. In contrast, during migration, a majority of experiments suggest that birds rely on the magnetic field as the primary source of compass information and use it to calibrate celestial compass cues, i.e. the relative saliency of magnetic and celestial cues is reversed. An alternative possibility, however, is suggested by several experiments in which birds exposed to a cue conflict during migration appear to have recalibrated the magnetic compass, i.e. their response is similar to that of birds exposed to cue conflicts during the premigratory season. The general pattern to emerge from these analyses is that birds exposed to the cue conflict with a view of the entire sunset sky tended to recalibrate the magnetic compass, regardless of whether the cue conflict occurred during the premigratory or migratory period. In contrast, birds exposed to the cue conflict in orientation funnels and registration cages that restricted their view of the region of sky near the horizon (as was generally the case in experiments carried out during the migratory season) did not recalibrate the magnetic compass but, instead, used the magnetic compass to calibrate the other celestial compass systems. If access to critical celestial cues, rather than the timing of exposure to the cue conflict (i.e. premigratory vs migratory), determines whether recalibration of the magnetic compass occurs, this suggests that under natural conditions there may be a single calibration reference for all of the compass systems of migratory birds that is derived from sunset (and possibly also sunrise) polarized light cues from the region of sky near the horizon. In cue-conflict experiments carried out during the migratory season, there was also an interesting asymmetry in the birds' response to magnetic fields shifted clockwise and counterclockwise relative to celestial cues. We discuss two possible explanations for these differences: (1) lateral asymmetry in the role of the right and left eye in mediating light-dependent magnetic compass orientation and (2) interference from the spectral and intensity distribution of skylight at sunset with the response of the light-dependent magnetic compass.

Environmental Cues and Attempts to Change in Daily Cannabis Users: An Intensive Longitudinal Study

PubMed Central

Hughes, John R.; Naud, Shelly; Budney, Alan J.; Fingar, James R.; Callas, Peter W.

2016-01-01

Introduction We tested whether environmental cues prompt or inhibit quit or reduction attempts among heavy cannabis users. Methods We recruited 196 daily cannabis users who intended to stop or reduce at some point in the next 3 months. Users called an Interactive Voice Response system daily over 3 months to report on cues that might prompt an attempt to quit or reduce (e.g., a request to stop), cues that might inhibit a quit/reduction attempt (e.g., someone offering cannabis), cannabis use, and attempts to stop or reduce cannabis. No treatment was provided. Results Our major findings were a) cost and health/psychological problems were the most common prompting cues, and seeing others use and being offered cannabis were the most common inhibiting cues, b) the number of different types of prompting cues prospectively predicted an increase in attempts to change in a dose-related manner, c) more proximal cues appeared to be more strongly related to change, d) requests to stop or reduce, and physical or psychological problems from cannabis, best predicted change attempts, and e) inhibiting cues did not consistently predict the probability of an attempt to change. Conclusion These preliminary results suggest several environmental cues prompt attempts to change cannabis use. Thus, interventions to increase the frequency of these cues, and specifically requests to stop or reduce cannabis use, and reinforcing concerns about health and mental adverse events from cannabis use may increase cannabis reduction or cessation. PMID:26872879

Environmental cues and attempts to change in daily cannabis users: An intensive longitudinal study.

PubMed

Hughes, John R; Naud, Shelly; Budney, Alan J; Fingar, James R; Callas, Peter W

2016-04-01

We tested whether environmental cues prompt or inhibit quit or reduction attempts among heavy cannabis users. We recruited 196 daily cannabis users who intended to stop or reduce at some point in the next 3 months. Users called an Interactive Voice Response system daily over 3 months to report on cues that might prompt an attempt to quit or reduce (e.g., a request to stop), cues that might inhibit a quit/reduction attempt (e.g., someone offering cannabis), cannabis use, and attempts to stop or reduce cannabis. No treatment was provided. Our major findings were (a) cost and health/psychological problems were the most common prompting cues, and seeing others use and being offered cannabis were the most common inhibiting cues, (b) the number of different types of prompting cues prospectively predicted an increase in attempts to change in a dose-related manner, (c) more proximal cues appeared to be more strongly related to change, (d) requests to stop or reduce, and physical or psychological problems from cannabis, best predicted change attempts, and (e) inhibiting cues did not consistently predict the probability of an attempt to change. These preliminary results suggest several environmental cues prompt attempts to change cannabis use. Thus, interventions to increase the frequency of these cues, and specifically requests to stop or reduce cannabis use, and reinforcing concerns about health and mental adverse events from cannabis use, may increase cannabis reduction or cessation. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Predator pursuit strategies: how do falcons and hawks chase prey?

NASA Astrophysics Data System (ADS)

Kane, Suzanne Amador; Zamani, Marjon; Fulton, Andrew; Rosenthal, Lee

2014-03-01

This study reports on experiments on falcons, goshawks and red-tailed hawks wearing miniature videocameras mounted on their backs or heads while pursuing flying or ground-based prey. Videos of hunts recorded by the raptors were analyzed to determine apparent prey positions on their visual fields during pursuits. These video data then were interpreted using computer simulations of pursuit steering laws observed in insects and mammals. A comparison of the empirical and modeling data indicates that falcons use cues due to the apparent motion of prey on the falcon's visual field to track and capture flying prey via a form of motion camouflage. The falcons also were found to maintain their prey's image at visual angles consistent with using their shallow fovea. Results for goshawks and red-tailed hawks were analyzed for a comparative study of how pursuits of ground-based prey by accipeters and buteos differ from those used by falcons chasing flying prey. These results should prove relevant for understanding the coevolution of pursuit and evasion, as well as the development of computer models of predation on flocks,and the integration of sensory and locomotion systems in biomimetic robots.

Expectancy modulates pupil size during endogenous orienting of spatial attention.

PubMed

Dragone, Alessio; Lasaponara, Stefano; Pinto, Mario; Rotondaro, Francesca; De Luca, Maria; Doricchi, Fabrizio

2018-05-01

fMRI investigations in healthy humans have documented phasic changes in the level of activation of the right temporal-parietal junction (TPJ) during cued voluntary orienting of spatial attention. Cues that correctly predict the position of upcoming targets in the majority of trials, i.e., predictive cues, produce higher deactivation of the right TPJ as compared with non-predictive cues. Since the right TPJ is the recipient of noradrenergic (NE) innervation, it has been hypothesised that changes in the level of TPJ activity are matched with changes in the level of NE activity. Based on aforementioned fMRI findings, this might imply that orienting with predictive cues is matched with different levels of NE activity as compared with non-predictive cues. To test this hypothesis, we measured changes in pupil dilation, an indirect index of NE activity, during voluntary orienting of attention with highly predictive (80% validity) or non-predictive (50% validity) cues. In agreement with current interpretations of the tonic/phasic activity of the Locus Coeruleus-Norepinephrinic system (LC-NE), we found that the steady level of cue predictiveness that characterised both the predictive and non-predictive conditions caused, across consecutive blocks of trials, a progressive decrement in pupil dilation during the baseline-fixation period that anticipated the cue period. With predictive cues we observed increased pupil dilation as compared with non-predictive cues. In addition, the relative reduction in pupil size observed with non-predictive cues increased as a function of cue-duration. These results show that changes in the predictiveness of cues that guide voluntary orienting of spatial attention are matched with changes in pupil dilation and, putatively, with corresponding changes in LC-NE activity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Motion Cueing Algorithm Development: Human-Centered Linear and Nonlinear Approaches

NASA Technical Reports Server (NTRS)

Houck, Jacob A. (Technical Monitor); Telban, Robert J.; Cardullo, Frank M.

2005-01-01

While the performance of flight simulator motion system hardware has advanced substantially, the development of the motion cueing algorithm, the software that transforms simulated aircraft dynamics into realizable motion commands, has not kept pace. Prior research identified viable features from two algorithms: the nonlinear "adaptive algorithm", and the "optimal algorithm" that incorporates human vestibular models. A novel approach to motion cueing, the "nonlinear algorithm" is introduced that combines features from both approaches. This algorithm is formulated by optimal control, and incorporates a new integrated perception model that includes both visual and vestibular sensation and the interaction between the stimuli. Using a time-varying control law, the matrix Riccati equation is updated in real time by a neurocomputing approach. Preliminary pilot testing resulted in the optimal algorithm incorporating a new otolith model, producing improved motion cues. The nonlinear algorithm vertical mode produced a motion cue with a time-varying washout, sustaining small cues for longer durations and washing out large cues more quickly compared to the optimal algorithm. The inclusion of the integrated perception model improved the responses to longitudinal and lateral cues. False cues observed with the NASA adaptive algorithm were absent. The neurocomputing approach was crucial in that the number of presentations of an input vector could be reduced to meet the real time requirement without degrading the quality of the motion cues.

The Instructed Learning of Form-Function Mappings in the English Article System

ERIC Educational Resources Information Center

Zhao, Helen; MacWhinney, Brian

2018-01-01

This article analyzes the instructed learning of the English article system by second language (L2) learners. The Competition Model (MacWhinney, 1987, 2012) was adopted as the theoretical framework for analyzing the cues to article usage and for designing effective computer-based article instruction. Study 1 found that article cues followed a…

The neural correlates of priming emotion and reward systems for conflict processing in alcoholics.

PubMed

Schulte, T; Jung, Y-C; Sullivan, E V; Pfefferbaum, A; Serventi, M; Müller-Oehring, E M

2017-12-01

Emotional dysregulation in alcoholism (ALC) may result from disturbed inhibitory mechanisms. We therefore tested emotion and alcohol cue reactivity and inhibitory processes using negative priming. To test the neural correlates of cue reactivity and negative priming, 26 ALC and 26 age-matched controls underwent functional MRI performing a Stroop color match-to-sample task. In cue reactivity trials, task-irrelevant emotion and alcohol-related pictures were interspersed between color samples and color words. In negative priming trials, pictures primed the semantic content of an alcohol or emotion Stroop word. Behaviorally, both groups showed response facilitation to picture cue trials and response inhibition to primed trials. For cue reactivity to emotion and alcohol pictures, ALC showed midbrain-limbic activation. By contrast, controls activated frontoparietal executive control regions. Greater midbrain-hippocampal activation in ALC correlated with higher amounts of lifetime alcohol consumption and higher anxiety. With negative priming, ALC exhibited frontal cortical but not midbrain-hippocampal activation, similar to the pattern observed in controls. Higher frontal activation to alcohol-priming correlated with less craving and to emotion-priming with fewer depressive symptoms. The findings suggest that neurofunctional systems in ALC can be primed to deal with upcoming emotion- and alcohol-related conflict and can overcome the prepotent midbrain-limbic cue reactivity response.

Re-calibration of the magnetic compass in hand-raised European robins (Erithacus rubecula)

PubMed Central

Alert, Bianca; Michalik, Andreas; Thiele, Nadine; Bottesch, Michael; Mouritsen, Henrik

2015-01-01

Migratory birds can use a variety of environmental cues for orientation. A primary calibration between the celestial and magnetic compasses seems to be fundamental prior to a bird’s first autumn migration. Releasing hand-raised or rescued young birds back into the wild might therefore be a problem because they might not have established a functional orientation system during their first calendar year. Here, we test whether hand-raised European robins that did not develop any functional compass before or during their first autumn migration could relearn to orient if they were exposed to natural celestial cues during the subsequent winter and spring. When tested in the geomagnetic field without access to celestial cues, these birds could orient in their species-specific spring migratory direction. In contrast, control birds that were deprived of any natural celestial cues throughout remained unable to orient. Our experiments suggest that European robins are still capable of establishing a functional orientation system after their first autumn. Although the external reference remains speculative, most likely, natural celestial cues enabled our birds to calibrate their magnetic compass. Our data suggest that avian compass systems are more flexible than previously believed and have implications for the release of hand-reared migratory birds. PMID:26388258

OH-58 Helicopter Transmission Failure Analysis

DTIC Science & Technology

1976-01-01

would require rigid stradle mountings in place of the overhung mountings currently on the plane- tary spider. However, there is a probability that...roller bearings with rigid stradle mounting to replace the overhung mounting. This change would re- duce the heat generation in the planet...Weapons System Manager requested NASA-Lewis Research Center’s assistance in upgrading the current OH-58 main rotor transmission in performance and

Neurite outgrowth at the interface of 2D and 3D growth environments

NASA Astrophysics Data System (ADS)

Kofron, Celinda M.; Fong, Vivian J.; Hoffman-Kim, Diane

2009-02-01

Growing neurons navigate complex environments, but in vitro systems for studying neuronal growth typically limit the cues to flat surfaces or a single type of cue, thereby limiting the resulting growth. Here we examined the growth of neurons presented with two-dimensional (2D) substrate-bound cues when these cues were presented in conjunction with a more complex three-dimensional (3D) architecture. Dorsal root ganglia (DRG) explants were cultured at the interface between a collagen I matrix and a glass coverslip. Laminin (LN) or chondroitin sulfate proteoglycans (CSPG) were uniformly coated on the surface of the glass coverslip or patterned in 50 µm tracks by microcontact printing. Quantitative analysis of neurite outgrowth with a novel grid system at multiple depths in the gel revealed several interesting trends. Most of the neurites extended at the surface of the gel when LN was presented whereas more neurites extended into the gel when CSPG was presented. Patterning of cues did not affect neurite density or depth of growth. However, neurite outgrowth near the surface of the gel aligned with LN patterns, and these extensions were significantly longer than neurites extended in other cultures. In interface cultures, DRG growth patterns varied with the type of cue where neurite density was higher in cultures presenting LN than in cultures presenting CSPG. These results represent an important step toward understanding how neurons integrate local structural and chemical cues to make net growth decisions.

The Effects of Pharmacological Opioid Blockade on Neural Measures of Drug Cue-Reactivity in Humans.

PubMed

Courtney, Kelly E; Ghahremani, Dara G; Ray, Lara A

2016-11-01

Interactions between dopaminergic and opioidergic systems have been implicated in the reinforcing properties of drugs of abuse. The present study investigated the effects of opioid blockade, via naltrexone, on functional magnetic resonance imaging (fMRI) measures during methamphetamine cue-reactivity to elucidate the role of endogenous opioids in the neural systems underlying drug craving. To investigate this question, non-treatment seeking individuals with methamphetamine use disorder (N=23; 74% male, mean age=34.70 (SD=8.95)) were recruited for a randomized, placebo controlled, within-subject design and underwent a visual methamphetamine cue-reactivity task during two blood-oxygen-level dependent (BOLD) fMRI sessions following 3 days of naltrexone (50 mg) and matched time for placebo. fMRI analyses tested naltrexone-induced differences in BOLD activation and functional connectivity during cue processing. The results showed that naltrexone administration reduced cue-reactivity in sensorimotor regions and related to altered functional connectivity of dorsal striatum, ventral tegmental area, and precuneus with frontal, visual, sensory, and motor-related regions. Naltrexone also weakened the associations between subjective craving and precuneus functional connectivity with sensorimotor regions and strengthened the associations between subjective craving and dorsal striatum and precuneus connectivity with frontal regions. In conclusion, this study provides the first evidence that opioidergic blockade alters neural responses to drug cues in humans with methamphetamine addiction and suggests that naltrexone may be reducing drug cue salience by decreasing the involvement of sensorimotor regions and by engaging greater frontal regulation over salience attribution.

Systemic treatment with d-fenfluramine, but not sibutramine, blocks cue-induced reinstatement of food-seeking behavior in the rat

PubMed Central

Pratt, Wayne E.; Ford, Ryan T.

2013-01-01

Individuals struggling with obesity often have difficulty maintaining dietary regimens. One source of dietary relapse is the reinstatement of previous feeding behaviors following the presentation of cues indicating the availability of palatable but highly caloric food reward. The drugs fenfluramine and sibutramine have previously been prescribed because they enhance satiety mechanisms and decrease meal size. However, it is unclear whether these anorectic agents are also effective in blocking the cue-induced reinstatement of food-seeking behaviors. In these three experiments, we compared the effects of systemic treatment of d-fenfluramine (3 mg/kg; N=11) and sibutramine (3 mg/kg; N=11) with that of the D1 antagonist SCH 23390 (6 μg/kg; N=11) at a dose that has previously been shown to attenuate cue-induced reinstatement. D-fenfluramine treatment blocked the cue’s ability to reinstate lever pressing as compared to the saline injection day. In contrast, sibutramine had no effect on cue-induced reinstatement; all animals reinstated their lever pressing during the first reinstatement test, and this was unaffected by sibutramine treatment. SCH 23390 treatment did not significantly reduce cue-induced reinstatement in this set of experiments. The results suggest that the motivational effects of d-fenfluramine is not limited to the promotion of satiety once a meal has been initiated, and demonstrate that some anorectic treatments may inhibit the effectiveness of conditioned cues to elicit relapse of food-seeking behavior. PMID:24157852

Water spray ventilator system for continuous mining machines

DOEpatents

Page, Steven J.; Mal, Thomas

1995-01-01

The invention relates to a water spray ventilator system mounted on a continuous mining machine to streamline airflow and provide effective face ventilation of both respirable dust and methane in underground coal mines. This system has two side spray nozzles mounted one on each side of the mining machine and six spray nozzles disposed on a manifold mounted to the underside of the machine boom. The six spray nozzles are angularly and laterally oriented on the manifold so as to provide non-overlapping spray patterns along the length of the cutter drum.

3D-additive manufactured optical mount

NASA Astrophysics Data System (ADS)

Mammini, Paul V.; Ciscel, David; Wooten, John

2015-09-01

The Area Defense Anti-Munitions (ADAM) is a low cost and effective high power laser weapon system. It's designed to address and negate important threats such as short-range rockets, UAVs, and small boats. Many critical optical components operate in the system. The optics and mounts must accommodate thermal and mechanical stresses, plus maintain an exceptional wave front during operation. Lockheed Martin Space Systems Company (LMSSC) developed, designed, and currently operates ADAM. This paper covers the design and development of a key monolithic, flexured, titanium mirror mount that was manufactured by CalRAM using additive processes.

Biochemical, spectroscopic and X-ray structural analysis of deuterated multicopper oxidase CueO prepared from a new expression construct for neutron crystallography.

PubMed

Akter, Mahfuza; Inoue, Chika; Komori, Hirofumi; Matsuda, Nana; Sakurai, Takeshi; Kataoka, Kunishige; Higuchi, Yoshiki; Shibata, Naoki

2016-10-01

Multicopper oxidases oxidize various phenolic and nonphenolic compounds by using molecular oxygen as an electron acceptor to produce water. A multicopper oxidase protein, CueO, from Escherichia coli is involved in copper homeostasis in the bacterial cell. Although X-ray crystallographic studies have been conducted, the reduction mechanism of oxygen and the proton-transfer pathway remain unclear owing to the difficulty in identifying H atoms from X-ray diffraction data alone. To elucidate the reaction mechanism using neutron crystallography, a preparation system for obtaining large, high-quality single crystals of deuterated CueO was developed. Tiny crystals were obtained from the deuterated CueO initially prepared from the original construct. The X-ray crystal structure of the deuterated CueO showed that the protein contained an incompletely truncated signal sequence at the N-terminus, which resulted in the heterogeneity of the protein sample for crystallization. Here, a new CueO expression system that had an HRV3C cleavage site just after the signal sequence was constructed. Deuterated CueO from the new construct was expressed in cells cultured in deuterated algae-extract medium and the signal sequence was completely eliminated by HRV3C protease. The deuteration level of the purified protein was estimated by MALDI-TOF mass spectrometry to be at least 83.2% compared with nondeuterated protein. Nondeuterated CueO crystallized in space group P2 1 , with unit-cell parameters a = 49.51, b = 88.79, c = 53.95 Å, β = 94.24°, and deuterated CueO crystallized in space group P2 1 2 1 2 1 , with unit-cell parameters a = 49.91, b = 106.92, c = 262.89 Å. The crystallographic parameters for the crystals of the new construct were different from those previously reported for nondeuterated crystals. The nondeuterated and deuterated CueO from the new construct had similar UV-Vis spectra, enzymatic activities and overall structure and geometry of the ligands of the Cu atoms in the active site to those of previously reported CueO structures. These results indicate that the CueO protein prepared using the new construct is suitable for further neutron diffraction studies.

Magnetic core mounting system

DOEpatents

Ronning, Jeffrey J.

2002-01-01

A mounting apparatus for an electromagnetic device such as a transformer of inductor includes a generally planar metallic plate as a first heat sink, and a metallic mounting cup as a second heat sink. The mounting cup includes a cavity configured to receive the electromagnetic device, the cavity being defined by a base, and an axially-extending annular sidewall extending from the base to a flange portion of the mounting cup. The mounting cup includes first and second passages for allowing the leads of first and second windings of the electromagnetic device to be routed out of the cavity. The cavity is filled with a polyurethane potting resin, and the mounting cup, including the potted electromagnetic device, is mounted to the plate heat sink using fasteners. The mounting cup, which surrounds the electromagnetic device, in combination with the potting resin provides improved thermal transfer to the plate heat sink, as well as providing resistance to vibration and shocks.

Acetylcholine Release in Prefrontal Cortex Promotes Gamma Oscillations and Theta–Gamma Coupling during Cue Detection

PubMed Central

Hetrick, Vaughn L.; Berke, Joshua D.

2017-01-01

The capacity for using external cues to guide behavior (“cue detection”) constitutes an essential aspect of attention and goal-directed behavior. The cortical cholinergic input system, via phasic increases in prefrontal acetylcholine release, plays an essential role in attention by mediating such cue detection. However, the relationship between cholinergic signaling during cue detection and neural activity dynamics in prefrontal networks remains unclear. Here we combined subsecond measures of cholinergic signaling, neurophysiological recordings, and cholinergic receptor blockade to delineate the cholinergic contributions to prefrontal oscillations during cue detection in rats. We first confirmed that detected cues evoke phasic acetylcholine release. These cholinergic signals were coincident with increased neuronal synchrony across several frequency bands and the emergence of theta–gamma coupling. Muscarinic and nicotinic cholinergic receptors both contributed specifically to gamma synchrony evoked by detected cues, but the effects of blocking the two receptor subtypes were dissociable. Blocking nicotinic receptors primarily attenuated high-gamma oscillations occurring during the earliest phases of the cue detection process, while muscarinic (M1) receptor activity was preferentially involved in the transition from high to low gamma power that followed and corresponded to the mobilization of networks involved in cue-guided decision making. Detected cues also promoted coupling between gamma and theta oscillations, and both nicotinic and muscarinic receptor activity contributed to this process. These results indicate that acetylcholine release coordinates neural oscillations during the process of cue detection. SIGNIFICANCE STATEMENT The capacity of learned cues to direct attention and guide responding (“cue detection”) is a key component of goal-directed behavior. Rhythmic neural activity and increases in acetylcholine release in the prefrontal cortex contribute to this process; however, the relationship between these neuronal mechanisms is not well understood. Using a combination of in vivo neurochemistry, neurophysiology, and pharmacological methods, we demonstrate that cue-evoked acetylcholine release, through distinct actions at both nicotinic and muscarinic receptors, triggers a procession of neural oscillations that map onto the multiple stages of cue detection. Our data offer new insights into cholinergic function by revealing the temporally orchestrated changes in prefrontal network synchrony modulated by acetylcholine release during cue detection. PMID:28213446

Motorized control for mirror mount apparatus

DOEpatents

Cutburth, Ronald W.

1989-01-01

A motorized control and automatic braking system for adjusting mirror mount apparatus is disclosed. The motor control includes a planetary gear arrangement to provide improved pitch adjustment capability while permitting a small packaged design. The motor control for mirror mount adjustment is suitable for laser beam propagation applications. The brake is a system of constant contact, floating detents which engage the planetary gear at selected between-teeth increments to stop rotation instantaneously when the drive motor stops.

Preliminary Design of a Modular Unmanned Research Vehicle. Volume 1. System Design Document

DTIC Science & Technology

1988-12-01

providing con- munications and restraint. 1-5 Tethered unpowered vehicle - an airplane-like body tether-mounted to an automobile , the auto providing...the velocity by towing. Auto-mounted vehicle - an airplane-like body rigidly mounted external to an automobile , the auto providing the velocity. Rail...accordingly. Based on this experiment, the MURV flight control system must be flexible in two ways: it should be reprogrammable for varying experimental

Social learning of predators in the dark: understanding the role of visual, chemical and mechanical information.

PubMed

Manassa, R P; McCormick, M I; Chivers, D P; Ferrari, M C O

2013-08-22

The ability of prey to observe and learn to recognize potential predators from the behaviour of nearby individuals can dramatically increase survival and, not surprisingly, is widespread across animal taxa. A range of sensory modalities are available for this learning, with visual and chemical cues being well-established modes of transmission in aquatic systems. The use of other sensory cues in mediating social learning in fishes, including mechano-sensory cues, remains unexplored. Here, we examine the role of different sensory cues in social learning of predator recognition, using juvenile damselfish (Amphiprion percula). Specifically, we show that a predator-naive observer can socially learn to recognize a novel predator when paired with a predator-experienced conspecific in total darkness. Furthermore, this study demonstrates that when threatened, individuals release chemical cues (known as disturbance cues) into the water. These cues induce an anti-predator response in nearby individuals; however, they do not facilitate learnt recognition of the predator. As such, another sensory modality, probably mechano-sensory in origin, is responsible for information transfer in the dark. This study highlights the diversity of sensory cues used by coral reef fishes in a social learning context.

Global Repetition Influences Contextual Cueing

PubMed Central

Zang, Xuelian; Zinchenko, Artyom; Jia, Lina; Li, Hong

2018-01-01

Our visual system has a striking ability to improve visual search based on the learning of repeated ambient regularities, an effect named contextual cueing. Whereas most of the previous studies investigated contextual cueing effect with the same number of repeated and non-repeated search displays per block, the current study focused on whether a global repetition frequency formed by different presentation ratios between the repeated and non-repeated configurations influence contextual cueing effect. Specifically, the number of repeated and non-repeated displays presented in each block was manipulated: 12:12, 20:4, 4:20, and 4:4 in Experiments 1–4, respectively. The results revealed a significant contextual cueing effect when the global repetition frequency is high (≥1:1 ratio) in Experiments 1, 2, and 4, given that processing of repeated displays was expedited relative to non-repeated displays. Nevertheless, the contextual cueing effect reduced to a non-significant level when the repetition frequency reduced to 4:20 in Experiment 3. These results suggested that the presentation frequency of repeated relative to the non-repeated displays could influence the strength of contextual cueing. In other words, global repetition statistics could be a crucial factor to mediate contextual cueing effect. PMID:29636716

Interaction of Object Binding Cues in Binaural Masking Pattern Experiments.

PubMed

Verhey, Jesko L; Lübken, Björn; van de Par, Steven

2016-01-01

Object binding cues such as binaural and across-frequency modulation cues are likely to be used by the auditory system to separate sounds from different sources in complex auditory scenes. The present study investigates the interaction of these cues in a binaural masking pattern paradigm where a sinusoidal target is masked by a narrowband noise. It was hypothesised that beating between signal and masker may contribute to signal detection when signal and masker do not spectrally overlap but that this cue could not be used in combination with interaural cues. To test this hypothesis an additional sinusoidal interferer was added to the noise masker with a lower frequency than the noise whereas the target had a higher frequency than the noise. Thresholds increase when the interferer is added. This effect is largest when the spectral interferer-masker and masker-target distances are equal. The result supports the hypothesis that modulation cues contribute to signal detection in the classical masking paradigm and that these are analysed with modulation bandpass filters. A monaural model including an across-frequency modulation process is presented that account for this effect. Interestingly, the interferer also affects dichotic thresholds indicating that modulation cues also play a role in binaural processing.

Cue-recruitment for extrinsic signals after training with low information stimuli.

PubMed

Jain, Anshul; Fuller, Stuart; Backus, Benjamin T

2014-01-01

Cue-recruitment occurs when a previously ineffective signal comes to affect the perceptual appearance of a target object, in a manner similar to the trusted cues with which the signal was put into correlation during training. Jain, Fuller and Backus reported that extrinsic signals, those not carried by the target object itself, were not recruited even after extensive training. However, recent studies have shown that training using weakened trusted cues can facilitate recruitment of intrinsic signals. The current study was designed to examine whether extrinsic signals can be recruited by putting them in correlation with weakened trusted cues. Specifically, we tested whether an extrinsic visual signal, the rotary motion direction of an annulus of random dots, and an extrinsic auditory signal, direction of an auditory pitch glide, can be recruited as cues for the rotation direction of a Necker cube. We found learning, albeit weak, for visual but not for auditory signals. These results extend the generality of the cue-recruitment phenomenon to an extrinsic signal and provide further evidence that the visual system learns to use new signals most quickly when other, long-trusted cues are unavailable or unreliable.

Global Repetition Influences Contextual Cueing.

PubMed

Zang, Xuelian; Zinchenko, Artyom; Jia, Lina; Assumpção, Leonardo; Li, Hong

2018-01-01

Our visual system has a striking ability to improve visual search based on the learning of repeated ambient regularities, an effect named contextual cueing. Whereas most of the previous studies investigated contextual cueing effect with the same number of repeated and non-repeated search displays per block, the current study focused on whether a global repetition frequency formed by different presentation ratios between the repeated and non-repeated configurations influence contextual cueing effect. Specifically, the number of repeated and non-repeated displays presented in each block was manipulated: 12:12, 20:4, 4:20, and 4:4 in Experiments 1-4, respectively. The results revealed a significant contextual cueing effect when the global repetition frequency is high (≥1:1 ratio) in Experiments 1, 2, and 4, given that processing of repeated displays was expedited relative to non-repeated displays. Nevertheless, the contextual cueing effect reduced to a non-significant level when the repetition frequency reduced to 4:20 in Experiment 3. These results suggested that the presentation frequency of repeated relative to the non-repeated displays could influence the strength of contextual cueing. In other words, global repetition statistics could be a crucial factor to mediate contextual cueing effect.

Analysis of engagement behavior in children during dyadic interactions using prosodic cues⋆

PubMed Central

Gupta, Rahul; Bone, Daniel; Lee, Sungbok; Narayanan, Shrikanth

2017-01-01

Child engagement is defined as the interaction of a child with his/her environment in a contextually appropriate manner. Engagement behavior in children is linked to socio-emotional and cognitive state assessment with enhanced engagement identified with improved skills. A vast majority of studies however rely solely, and often implicitly, on subjective perceptual measures of engagement. Access to automatic quantification could assist researchers/clinicians to objectively interpret engagement with respect to a target behavior or condition, and furthermore inform mechanisms for improving engagement in various settings. In this paper, we present an engagement prediction system based exclusively on vocal cues observed during structured interaction between a child and a psychologist involving several tasks. Specifically, we derive prosodic cues that capture engagement levels across the various tasks. Our experiments suggest that a child’s engagement is reflected not only in the vocalizations, but also in the speech of the interacting psychologist. Moreover, we show that prosodic cues are informative of the engagement phenomena not only as characterized over the entire task (i.e., global cues), but also in short term patterns (i.e., local cues). We perform a classification experiment assigning the engagement of a child into three discrete levels achieving an unweighted average recall of 55.8% (chance is 33.3%). While the systems using global cues and local level cues are each statistically significant in predicting engagement, we obtain the best results after fusing these two components. We perform further analysis of the cues at local and global levels to achieve insights linking specific prosodic patterns to the engagement phenomenon. We observe that while the performance of our model varies with task setting and interacting psychologist, there exist universal prosodic patterns reflective of engagement. PMID:28713198

The plastic ear and perceptual relearning in auditory spatial perception

PubMed Central

Carlile, Simon

2014-01-01

The auditory system of adult listeners has been shown to accommodate to altered spectral cues to sound location which presumably provides the basis for recalibration to changes in the shape of the ear over a life time. Here we review the role of auditory and non-auditory inputs to the perception of sound location and consider a range of recent experiments looking at the role of non-auditory inputs in the process of accommodation to these altered spectral cues. A number of studies have used small ear molds to modify the spectral cues that result in significant degradation in localization performance. Following chronic exposure (10–60 days) performance recovers to some extent and recent work has demonstrated that this occurs for both audio-visual and audio-only regions of space. This begs the questions as to the teacher signal for this remarkable functional plasticity in the adult nervous system. Following a brief review of influence of the motor state in auditory localization, we consider the potential role of auditory-motor learning in the perceptual recalibration of the spectral cues. Several recent studies have considered how multi-modal and sensory-motor feedback might influence accommodation to altered spectral cues produced by ear molds or through virtual auditory space stimulation using non-individualized spectral cues. The work with ear molds demonstrates that a relatively short period of training involving audio-motor feedback (5–10 days) significantly improved both the rate and extent of accommodation to altered spectral cues. This has significant implications not only for the mechanisms by which this complex sensory information is encoded to provide spatial cues but also for adaptive training to altered auditory inputs. The review concludes by considering the implications for rehabilitative training with hearing aids and cochlear prosthesis. PMID:25147497

Engineering data exchange.

PubMed

Moore, M

2001-11-01

Mount Clemens General Hospsital, Mount Clemens, Mich. performance anomalies due to multiple interfaces with separate systems. implementation of an interface engine. improved management of data exchange among disparate systems. up-front studies of vendor offerings, potential problems, and long-term needs.

Design of an automated cart and mount for a hyperspectral imaging system to be used in produce fields

NASA Astrophysics Data System (ADS)

Lefcourt, Alan M.; Kistler, Ross; Gadsden, S. Andrew

2016-05-01

The goal of this project was to construct a cart and a mounting system that would allow a hyperspectral laser-induced fluorescence imaging system (HLIFIS) to be used to detect fecal material in produce fields. Fecal contaminated produce is a recognized food safety risk. Previous research demonstrated the HLIFIS could detect fecal contamination in a laboratory setting. A cart was designed and built, and then tested to demonstrate that the cart was capable of moving at constant speeds or at precise intervals. A mounting system was designed and built to facilitate the critical alignment of the camera's imaging and the laser's illumination fields, and to allow the HLIFIS to be used in both field and laboratory settings without changing alignments. A hardened mount for the Powell lens that is used to produce the appropriate illumination profile was also designed, built, and tested.

Determination of optimum mounting configurations for flat-plate photovoltaic modules based on a structured field experiment and simulated results from PVFORM, a photovoltaic system performance model

NASA Astrophysics Data System (ADS)

Menicucci, D. F.

1986-01-01

The performance of a photovoltaic (PV) system is affected by its mounting configuration. The optimal configuration is unclear because of lack of experience and data. Sandia National Laboratories, Albuquerque (SNLA), has conducted a controlled field experiment to compare four types of the most common module mounting. The data from the experiment were used to verify the accuracy of PVFORM, a new computer program that simulates PV performance. PVFORM was then used to simulate the performance of identical PV modules on different mounting configurations at 10 sites throughout the US. This report describes the module mounting configurations, the experimental methods used, the specialized statistical techniques used in the analysis, and the final results of the effort. The module mounting configurations are rank ordered at each site according to their annual and seasonal energy production performance, and each is briefly discussed in terms of its advantages and disadvantages in various applications.

Gazing at me: the importance of social meaning in understanding direct-gaze cues.

PubMed

de C Hamilton, Antonia F

2016-01-19

Direct gaze is an engaging and important social cue, but the meaning of direct gaze depends heavily on the surrounding context. This paper reviews some recent studies of direct gaze, to understand more about what neural and cognitive systems are engaged by this social cue and why. The data show that gaze can act as an arousal cue and can modulate actions, and can activate brain regions linked to theory of mind and self-related processing. However, all these results are strongly modulated by the social meaning of a gaze cue and by whether participants believe that another person is really watching them. The implications of these contextual effects and audience effects for our theories of gaze are considered. © 2015 The Author(s).

Obtaining Acoustic Cue Rate Estimates for Some Mysticete Species Using Existing Data

DTIC Science & Technology

2015-09-30

several species of endangered mysticete whales on and near U.S. Navy ranges, using existing recordings from both the SCORE and PMRF hydrophone...Mysticete Species using Existing Data Tyler A. Helble Marine Mammals and Autonomous Underwater Vehicles, Code 56440 Space and Naval Warfare Systems...acoustics, one must know the species -specific average cue rate, which is the average number of calls produced per animal per time. The cue rate can

Imaging the Mount St. Helens Magmatic Systems using Magnetotellurics

NASA Astrophysics Data System (ADS)

Hill, G. J.; Caldwell, T. G.; Heise, W.; Bibby, H. M.; Chertkoff, D. G.; Burgess, M. K.; Cull, J. P.; Cas, R. A.

2009-05-01

A detailed magnetotelluric survey of Mount St. Helens shows that a conduit like zone of high electrical conductivity beneath the volcano is connected to a larger zone of high conductivity at 15 km depth that extends eastward to Mount Adams. We interpret this zone to be a region of connected melt that acts as the reservoir for the silicic magma being extruded at the time of the magnetotelluric survey. This interpretation is consistent with a mid-crustal origin for the silicic component of the Mount St. Helens' magmas and provides an elegant explanation for a previously unexplained feature of the seismicity observed at the time of the catastrophic eruption in 1980. This zone of high mid-crustal conductivity extends northwards to near Mount Rainier suggesting a single region of connected melt comparable in size to the largest silicic volcanic systems known.

A multiple pointing-mount control strategy for space platforms

NASA Technical Reports Server (NTRS)

Johnson, C. D.

1992-01-01

A new disturbance-adaptive control strategy for multiple pointing-mount space platforms is proposed and illustrated by consideration of a simplified 3-link dynamic model of a multiple pointing-mount space platform. Simulation results demonstrate the effectiveness of the new platform control strategy. The simulation results also reveal a system 'destabilization phenomena' that can occur if the set of individual platform-mounted experiment controllers are 'too responsive.'

Ocean floor mounting of wave energy converters

DOEpatents

Siegel, Stefan G

2015-01-20

A system for mounting a set of wave energy converters in the ocean includes a pole attached to a floor of an ocean and a slider mounted on the pole in a manner that permits the slider to move vertically along the pole and rotate about the pole. The wave energy converters can then be mounted on the slider to allow adjustment of the depth and orientation of the wave energy converters.

Three-Dimensional Modeling of Mount Etna Volcano: Volume Assessment, Trend of Eruption Rates, and Geodynamic Significance

NASA Astrophysics Data System (ADS)

Barreca, Giovanni; Branca, Stefano; Monaco, Carmelo

2018-03-01

3-D modeling of Mount Etna, the largest and most active volcano in Europe, has for the first time enabled acquiring new information on the volumes of products emitted during the volcanic phases that have formed Mount Etna and particularly during the last 60 ka, an issue previously not fully addressed. Volumes emitted over time allow determining the trend of eruption rates during the volcano's lifetime, also highlighting a drastic increase of emitted products in the last 15 ka. The comparison of Mount Etna's eruption rates with those of other volcanic systems in different geodynamic frameworks worldwide revealed that since 60 ka ago, eruption rates have reached a value near to that of oceanic-arc volcanic systems, although Mount Etna is considered a continental rift strato-volcano. This finding agrees well with previous studies on a possible transition of Mount Etna's magmatic source from plume-related to island-arc related. As suggested by tomographic studies, trench-parallel breakoff of the Ionian slab has occurred north of Mount Etna. Slab gateway formation right between the Aeolian magmatic province and the Mount Etna area probably induced a previously softened and fluid-enriched suprasubduction mantle wedge to flow toward the volcano with consequent magmatic source mixing.

Follow your nose: Implicit spatial processing within the chemosensory systems.

PubMed

Wudarczyk, Olga A; Habel, Ute; Turetsky, Bruce I; Gur, Raquel E; Kellermann, Thilo; Schneider, Frank; Moessnang, Carolin

2016-11-01

Although most studies agree that humans cannot smell in stereo, it was recently suggested that olfactory localization is possible when assessed implicitly. In a spatial cueing paradigm, lateralized olfactory cues impaired the detection of congruently presented visual targets, an effect contrary to the typical facilitation observed in other sensory domains. Here, we examined the specificity and the robustness of this finding by studying implicit localization abilities in another chemosensory system and by accounting for possible confounds in a modified paradigm. Sixty participants completed a spatial cueing task along with an explicit localization task, using trigeminal (Experiment 1) and olfactory (Experiment 2) stimuli. A control task was implemented to control for residual somatosensory stimulation (Experiment 3). In the trigeminal experiment, stimuli were localized with high accuracy on the explicit level, while the cueing effect in form of facilitation was limited to response accuracy. In the olfactory experiment, responses were slowed by congruent cues on the implicit level, while no explicit localization was observed. Our results point to the robustness of the olfactory interference effect, corroborating the implicit-explicit dissociation of olfactory localization, and challenging the view that humans lost the ability to extract spatial information from smell. The absence of a similar interference for trigeminal cues suggests distinct implicit spatial processing mechanisms within the chemosensory systems. Moreover, the lack of a typical facilitation effect in the trigeminal domain points to important differences from spatial information processing in other, nonchemosensory domains. The possible mechanisms driving the effects are discussed. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Shuttle vehicle and mission simulation requirements report, volume 1

NASA Technical Reports Server (NTRS)

Burke, J. F.

1972-01-01

The requirements for the space shuttle vehicle and mission simulation are developed to analyze the systems, mission, operations, and interfaces. The requirements are developed according to the following subject areas: (1) mission envelope, (2) orbit flight dynamics, (3) shuttle vehicle systems, (4) external interfaces, (5) crew procedures, (6) crew station, (7) visual cues, and (8) aural cues. Line drawings and diagrams of the space shuttle are included to explain the various systems and components.

Appetitive startle modulation in the human laboratory predicts Cannabis craving in the natural environment.

PubMed

Mereish, Ethan H; Padovano, Hayley Treloar; Wemm, Stephanie; Miranda, Robert

2018-07-01

Drug-related cues evoke craving and stimulate motivational systems in the brain. The acoustic startle reflex captures activation of these motivational processes and affords a unique measure of reactivity to drug cues. This study examined the effects of cannabis-related cues on subjective and eye blink startle reactivity in the human laboratory and tested whether these effects predicted youth's cue-elicited cannabis craving in the natural environment. Participants were 55 frequent cannabis users, ages 16 to 24 years (M = 19.9, SD = 1.9; 55% male; 56% met criteria for cannabis dependence), who were recruited from a clinical trial to reduce cannabis use. Eye blink electromyographic activity was recorded in response to acoustic probes that elicited startle reactivity while participants viewed pleasant, unpleasant, neutral, and cannabis picture cues. Following the startle assessment, participants completed an ecological momentary assessment protocol that involved repeated assessments of cue-elicited craving in real time in their real-world environments. Multilevel models included the presence or absence of visible cannabis cues in the natural environment, startle magnitude, and the cross-level interaction of cues by startle to test whether cue-modulated startle reactivity in the laboratory was associated with cue-elicited craving in the natural environment. Analyses showed that cannabis-related stimuli evoked an appetitive startle response pattern in the laboratory, and this effect was associated with increased cue-elicited craving in the natural environment, b = - 0.15, p = .022, 95% CI [- 0.28, - 0.02]. Pleasant stimuli also evoked an appetitive response pattern, but in this case, blunted response was associated with increased cue-elicited craving in the natural environment, b = 0.27, p < .001, 95% CI [0.12, 0.43]. Our findings support cue-modulated startle reactivity as an index of the phenotypic expression of cue-elicited cannabis craving.

Role of Self-Generated Odor Cues in Contextual Representation

PubMed Central

Aikath, Devdeep; Weible, Aldis P; Rowland, David C; Kentros, Clifford G

2014-01-01

As first demonstrated in the patient H.M., the hippocampus is critically involved in forming episodic memories, the recall of “what” happened “where” and “when.” In rodents, the clearest functional correlate of hippocampal primary neurons is the place field: a cell fires predominantly when the animal is in a specific part of the environment, typically defined relative to the available visuospatial cues. However, rodents have relatively poor visual acuity. Furthermore, they are highly adept at navigating in total darkness. This raises the question of how other sensory modalities might contribute to a hippocampal representation of an environment. Rodents have a highly developed olfactory system, suggesting that cues such as odor trails may be important. To test this, we familiarized mice to a visually cued environment over a number of days while maintaining odor cues. During familiarization, self-generated odor cues unique to each animal were collected by re-using absorbent paperboard flooring from one session to the next. Visual and odor cues were then put in conflict by counter-rotating the recording arena and the flooring. Perhaps surprisingly, place fields seemed to follow the visual cue rotation exclusively, raising the question of whether olfactory cues have any influence at all on a hippocampal spatial representation. However, subsequent removal of the familiar, self-generated odor cues severely disrupted both long-term stability and rotation to visual cues in a novel environment. Our data suggest that odor cues, in the absence of additional rule learning, do not provide a discriminative spatial signal that anchors place fields. Such cues do, however, become integral to the context over time and exert a powerful influence on the stability of its hippocampal representation. © 2014 The Authors. Hippocampus Published by Wiley Periodicals, Inc. PMID:24753119

Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation

PubMed Central

Gilchrist, Christopher L.; Ruch, David S.; Little, Dianne; Guilak, Farshid

2014-01-01

Tissue and biomaterial microenvironments provide architectural cues that direct important cell behaviors including cell shape, alignment, migration, and resulting tissue formation. These architectural features may be presented to cells across multiple length scales, from nanometers to millimeters in size. In this study, we examined how architectural cues at two distinctly different length scales, “micro-scale” cues on the order of ~1–2 μm, and “meso-scale” cues several orders of magnitude larger (>100 μm), interact to direct aligned neo-tissue formation. Utilizing a micro-photopatterning (μPP) model system to precisely arrange cell-adhesive patterns, we examined the effects of substrate architecture at these length scales on human mesenchymal stem cell (hMSC) organization, gene expression, and fibrillar collagen deposition. Both micro- and meso-scale architectures directed cell alignment and resulting tissue organization, and when combined, meso cues could enhance or compete against micro-scale cues. As meso boundary aspect ratios were increased, meso-scale cues overrode micro-scale cues and controlled tissue alignment, with a characteristic critical width (~500 μm) similar to boundary dimensions that exist in vivo in highly aligned tissues. Meso-scale cues acted via both lateral confinement (in a cell-density-dependent manner) and by permitting end-to-end cell arrangements that yielded greater fibrillar collagen deposition. Despite large differences in fibrillar collagen content and organization between μPP architectural conditions, these changes did not correspond with changes in gene expression of key matrix or tendon-related genes. These findings highlight the complex interplay between geometric cues at multiple length scales and may have implications for tissue engineering strategies, where scaffold designs that incorporate cues at multiple length scales could improve neo-tissue organization and resulting functional outcomes. PMID:25263687

Surface-illuminant ambiguity and color constancy: effects of scene complexity and depth cues.

PubMed

Kraft, James M; Maloney, Shannon I; Brainard, David H

2002-01-01

Two experiments were conducted to study how scene complexity and cues to depth affect human color constancy. Specifically, two levels of scene complexity were compared. The low-complexity scene contained two walls with the same surface reflectance and a test patch which provided no information about the illuminant. In addition to the surfaces visible in the low-complexity scene, the high-complexity scene contained two rectangular solid objects and 24 paper samples with diverse surface reflectances. Observers viewed illuminated objects in an experimental chamber and adjusted the test patch until it appeared achromatic. Achromatic settings made tinder two different illuminants were used to compute an index that quantified the degree of constancy. Two experiments were conducted: one in which observers viewed the stimuli directly, and one in which they viewed the scenes through an optical system that reduced cues to depth. In each experiment, constancy was assessed for two conditions. In the valid-cue condition, many cues provided valid information about the illuminant change. In the invalid-cue condition, some image cues provided invalid information. Four broad conclusions are drawn from the data: (a) constancy is generally better in the valid-cue condition than in the invalid-cue condition: (b) for the stimulus configuration used, increasing image complexity has little effect in the valid-cue condition but leads to increased constancy in the invalid-cue condition; (c) for the stimulus configuration used, reducing cues to depth has little effect for either constancy condition: and (d) there is moderate individual variation in the degree of constancy exhibited, particularly in the degree to which the complexity manipulation affects performance.

Evaluating Health Advice in a Web 2.0 Environment: The Impact of Multiple User-Generated Factors on HIV Advice Perceptions.

PubMed

Walther, Joseph B; Jang, Jeong-Woo; Hanna Edwards, Ashley A

2018-01-01

Unlike traditional media, social media systems often present information of different types from different kinds of contributors within a single message pane, a juxtaposition of potential influences that challenges traditional health communication processing. One type of social media system, question-and-answer advice systems, provides peers' answers to health-related questions, which yet other peers read and rate. Responses may appear good or bad, responders may claim expertise, and others' aggregated evaluations of an answer's usefulness may affect readers' judgments. An experiment explored how answer feasibility, expertise claims, and user-generated ratings affected readers' assessments of advice about anonymous HIV testing. Results extend the heuristic-systematic model of persuasion (Chaiken, 1980) and warranting theory (Walther & Parks, 2002). Information that is generally associated with both systematic and heuristic processes influenced readers' evaluations. Moreover, content-level cues affected judgments about message sources unexpectedly. When conflicting cues were present, cues with greater warranting value (consensus user-generated ratings) had greater influence on outcomes than less warranted cues (self-promoted expertise). Findings present a challenge to health professionals' concerns about the reliability of online health information systems.

Inhibition of protein synthesis but not β-adrenergic receptors blocks reconsolidation of a cocaine-associated cue memory

PubMed Central

Dunbar, Amber B.

2016-01-01

Previously consolidated memories have the potential to enter a state of lability upon memory recall, during which time the memory can be altered before undergoing an additional consolidation-like process and being stored again as a long-term memory. Blocking reconsolidation of aberrant memories has been proposed as a potential treatment for psychiatric disorders including addiction. Here we investigated of the effect of systemically administering the protein synthesis inhibitor cycloheximide or the β-adrenergic antagonist propranolol on reconsolidation. Rats were trained to self-administer cocaine, during which each lever press resulted in the presentation of a cue paired with an intravenous infusion of cocaine. After undergoing lever press extinction to reduce operant responding, the cue memory was reactivated and rats were administered systemic injections of propranolol, cycloheximide, or vehicle. Post-reactivation cycloheximide, but not propranolol, resulted in a reactivation-dependent decrease in cue-induced reinstatement, indicative of reconsolidation blockade by protein synthesis inhibition. The present data indicate that systemically targeting protein synthesis as opposed to the β-adrenergic system may more effectively attenuate the reconsolidation of a drug-related memory and decrease drug-seeking behavior. PMID:27421890

Inhibition of protein synthesis but not β-adrenergic receptors blocks reconsolidation of a cocaine-associated cue memory.

PubMed

Dunbar, Amber B; Taylor, Jane R

2016-08-01

Previously consolidated memories have the potential to enter a state of lability upon memory recall, during which time the memory can be altered before undergoing an additional consolidation-like process and being stored again as a long-term memory. Blocking reconsolidation of aberrant memories has been proposed as a potential treatment for psychiatric disorders including addiction. Here we investigated of the effect of systemically administering the protein synthesis inhibitor cycloheximide or the β-adrenergic antagonist propranolol on reconsolidation. Rats were trained to self-administer cocaine, during which each lever press resulted in the presentation of a cue paired with an intravenous infusion of cocaine. After undergoing lever press extinction to reduce operant responding, the cue memory was reactivated and rats were administered systemic injections of propranolol, cycloheximide, or vehicle. Post-reactivation cycloheximide, but not propranolol, resulted in a reactivation-dependent decrease in cue-induced reinstatement, indicative of reconsolidation blockade by protein synthesis inhibition. The present data indicate that systemically targeting protein synthesis as opposed to the β-adrenergic system may more effectively attenuate the reconsolidation of a drug-related memory and decrease drug-seeking behavior. © 2016 Dunbar and Taylor; Published by Cold Spring Harbor Laboratory Press.

Shuttle Hitchhiker Experiment Launcher System (SHELS)

NASA Technical Reports Server (NTRS)

Daelemans, Gerry

1999-01-01

NASA's Goddard Space Flight Center Shuttle Small Payloads Project (SSPP), in partnership with the United States Air Force and NASA's Explorer Program, is developing a Shuttle based launch system called SHELS (Shuttle Hitchhiker Experiment Launcher System), which shall be capable of launching up to a 400 pound spacecraft from the Shuttle cargo bay. SHELS consists of a Marman band clamp push-plate ejection system mounted to a launch structure; the launch structure is mounted to one Orbiter sidewall adapter beam. Avionics mounted to the adapter beam will interface with Orbiter electrical services and provide optional umbilical services and ejection circuitry. SHELS provides an array of manifesting possibilities to a wide range of satellites.

Obstacles encountered in the development of the low vision enhancement system.

PubMed

Massof, R W; Rickman, D L

1992-01-01

The Johns Hopkins Wilmer Eye Institute and the NASA Stennis Space Center are collaborating on the development of a new high technology low vision aid called the Low Vision Enhancement System (LVES). The LVES consists of a binocular head-mounted video display system, video cameras mounted on the head-mounted display, and real-time video image processing in a system package that is battery powered and portable. Through a phased development approach, several generations of the LVES can be made available to the patient in a timely fashion. This paper describes the LVES project with major emphasis on technical problems encountered or anticipated during the development process.

Determination of the maximum MGS mounting height : phase I crash testing.

DOT National Transportation Integrated Search

2012-03-09

Post-and-rail guardrail systems encounter environmental conditions, such as severe frost heave or erosion, which : may drastically affect the post embedment depth and rail mounting height. In addition, guardrail systems may be designed : to accommoda...

Determination of the maximum MGS mounting height : phase II detailed analysis with LS-DYNA.

DOT National Transportation Integrated Search

2012-12-01

Determination of the maximum Midwest Guardrail System (MGS) mounting height was performed in two phases. : Phase I concentrated on crash testing: two full-scale crash tests were performed on the MGS with top-rail mounting heights : of 34 in. (864 mm)...

The Combat Vehicle Command and Control System. Combat Performance of Armor Battalions Using Interactive Simulation

DTIC Science & Technology

1994-01-31

ncluded the Commander’s Independent Thermal Viewer and a Command and Control display. Using 1 tank simulators in the Mounted Warfare Test Bed at Fort...CCD), the Commander’s Independent Thermal Viewer (CITV), and digital TOC workstations. Using autoloading tank simulators in the Mounted Warfare Test...identifying ways that the CVCC system might best benefit the battlefield commander, and potential modifications to mounted warfare TTPs. Another area of

Feasibility Study of a Barge Mounted System for Treatment of Sewage from Army Watercraft Holding Tank

DTIC Science & Technology

1980-10-01

coarse solids removal followed by a packed bed filter, activated carbon (for soluble organic removal ) and effluent chlorination prior to discharge...mounted blackwater treatment systems. 29. Comparison of four types of coarse solids removal methods........ 86 for barge mounted physical/chemical...then 904 BOOD,"’ ’ COD and T-PO4 removal ; efluent ollform densities’< ’l’MPN/ 100 ml. Additional Comments: Figure 1. Representative bibliographical

Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues.

PubMed

Young, Kimberly A; Franklin, Teresa R; Roberts, David C S; Jagannathan, Kanchana; Suh, Jesse J; Wetherill, Reagan R; Wang, Ze; Kampman, Kyle M; O'Brien, Charles P; Childress, Anna Rose

2014-04-02

Relapse is a widely recognized and difficult to treat feature of the addictions. Substantial evidence implicates cue-triggered activation of the mesolimbic dopamine system as an important contributing factor. Even drug cues presented outside of conscious awareness (i.e., subliminally) produce robust activation within this circuitry, indicating the sensitivity and vulnerability of the brain to potentially problematic reward signals. Because pharmacological agents that prevent these early cue-induced responses could play an important role in relapse prevention, we examined whether baclofen-a GABAB receptor agonist that reduces mesolimbic dopamine release and conditioned drug responses in laboratory animals-could inhibit mesolimbic activation elicited by subliminal cocaine cues in cocaine-dependent individuals. Twenty cocaine-dependent participants were randomized to receive baclofen (60 mg/d; 20 mg t.i.d.) or placebo. Event-related BOLD fMRI and a backward-masking paradigm were used to examine the effects of baclofen on subliminal cocaine (vs neutral) cues. Sexual and aversive cues were included to examine specificity. We observed that baclofen-treated participants displayed significantly less activation in response to subliminal cocaine (vs neutral) cues, but not sexual or aversive (vs neutral) cues, than placebo-treated participants in a large interconnected bilateral cluster spanning the ventral striatum, ventral pallidum, amygdala, midbrain, and orbitofrontal cortex (voxel threshold p < 0.005; cluster corrected at p < 0.05). These results suggest that baclofen may inhibit the earliest type of drug cue-induced motivational processing-that which occurs outside of awareness-before it evolves into a less manageable state.

Nipping Cue Reactivity in the Bud: Baclofen Prevents Limbic Activation Elicited by Subliminal Drug Cues

PubMed Central

Young, Kimberly A.; Franklin, Teresa R.; Roberts, David C.S.; Jagannathan, Kanchana; Suh, Jesse J.; Wetherill, Reagan R.; Wang, Ze; Kampman, Kyle M.; O'Brien, Charles P.

2014-01-01

Relapse is a widely recognized and difficult to treat feature of the addictions. Substantial evidence implicates cue-triggered activation of the mesolimbic dopamine system as an important contributing factor. Even drug cues presented outside of conscious awareness (i.e., subliminally) produce robust activation within this circuitry, indicating the sensitivity and vulnerability of the brain to potentially problematic reward signals. Because pharmacological agents that prevent these early cue-induced responses could play an important role in relapse prevention, we examined whether baclofen—a GABAB receptor agonist that reduces mesolimbic dopamine release and conditioned drug responses in laboratory animals—could inhibit mesolimbic activation elicited by subliminal cocaine cues in cocaine-dependent individuals. Twenty cocaine-dependent participants were randomized to receive baclofen (60 mg/d; 20 mg t.i.d.) or placebo. Event-related BOLD fMRI and a backward-masking paradigm were used to examine the effects of baclofen on subliminal cocaine (vs neutral) cues. Sexual and aversive cues were included to examine specificity. We observed that baclofen-treated participants displayed significantly less activation in response to subliminal cocaine (vs neutral) cues, but not sexual or aversive (vs neutral) cues, than placebo-treated participants in a large interconnected bilateral cluster spanning the ventral striatum, ventral pallidum, amygdala, midbrain, and orbitofrontal cortex (voxel threshold p < 0.005; cluster corrected at p < 0.05). These results suggest that baclofen may inhibit the earliest type of drug cue-induced motivational processing—that which occurs outside of awareness—before it evolves into a less manageable state. PMID:24695721

Mount control system of the ASTRI SST-2M prototype for the Cherenkov Telescope Array

NASA Astrophysics Data System (ADS)

Antolini, Elisa; Tosti, Gino; Tanci, Claudio; Bagaglia, Marco; Canestrari, Rodolfo; Cascone, Enrico; Gambini, Giorgio; Nucciarelli, Giuliano; Pareschi, Giovanni; Scuderi, Salvo; Stringhetti, Luca; Busatta, Andrea; Giacomel, Stefano; Marchiori, Gianpietro; Manfrin, Cristiana; Marcuzzi, Enrico; Di Michele, Daniele; Grigolon, Carlo; Guarise, Paolo

2016-08-01

The ASTRI SST-2M telescope is an end-to-end prototype proposed for the Small Size class of Telescopes (SST) of the future Cherenkov Telescope Array (CTA). The prototype is installed in Italy at the INAF observing station located at Serra La Nave on Mount Etna (Sicily) and it was inaugurated in September 2014. This paper presents the software and hardware architecture and development of the system dedicated to the control of the mount, health, safety and monitoring systems of the ASTRI SST-2M telescope prototype. The mount control system installed on the ASTRI SST-2M telescope prototype makes use of standard and widely deployed industrial hardware and software. State of the art of the control and automation industries was selected in order to fulfill the mount related functional and safety requirements with assembly compactness, high reliability, and reduced maintenance. The software package was implemented with the Beckhoff TwinCAT version 3 environment for the software Programmable Logical Controller (PLC), while the control electronics have been chosen in order to maximize the homogeneity and the real time performance of the system. The integration with the high level controller (Telescope Control System) has been carried out by choosing the open platform communications Unified Architecture (UA) protocol, supporting rich data model while offering compatibility with the PLC platform. In this contribution we show how the ASTRI approach for the design and implementation of the mount control system has made the ASTRI SST-2M prototype a standalone intelligent machine, able to fulfill requirements and easy to be integrated in an array configuration such as the future ASTRI mini-array proposed to be installed at the southern site of the Cherenkov Telescope Array (CTA).

Geometrical and optical calibration of a vehicle-mounted IR imager for land mine localization

NASA Astrophysics Data System (ADS)

Aitken, Victor C.; Russell, Kevin L.; McFee, John E.

2000-08-01

Many present day vehicle-mounted landmine detection systems use IR imagers. Information furnished by these imaging systems usually consists of video and the location of targets within the video. In multisensor systems employing data fusion, there is a need to convert sensor information to a common coordinate system that all sensors share.

Effects of Head-Mounted Display on the Oculomotor System and Refractive Error in Normal Adolescents.

PubMed

Ha, Suk-Gyu; Na, Kun-Hoo; Kweon, Il-Joo; Suh, Young-Woo; Kim, Seung-Hyun

2016-07-01

To investigate the clinical effects of head-mounted display on the refractive error and oculomotor system in normal adolescents. Sixty volunteers (age: 13 to 18 years) watched a three-dimensional movie and virtual reality application of head-mounted display for 30 minutes. The refractive error (diopters [D]), angle of deviation (prism diopters [PD]) at distance (6 m) and near (33 cm), near point of accommodation, and stereoacuity were measured before, immediately after, and 10 minutes after watching the head-mounted display. The refractive error was presented as spherical equivalent (SE). Refractive error was measured repeatedly after every 10 minutes when a myopic shift greater than 0.15 D was observed after watching the head-mounted display. The mean age of the participants was 14.7 ± 1.3 years and the mean SE before watching head-mounted display was -3.1 ± 2.6 D. One participant in the virtual reality application group was excluded due to motion sickness and nausea. After 30 minutes of watching the head-mounted display, the SE, near point of accommodation, and stereoacuity in both eyes did not change significantly (all P > .05). Immediately after watching the head-mounted display, esophoric shift was observed (0.6 ± 1.5 to 0.2 ± 1.5 PD), although it was not significant (P = .06). Transient myopic shifts of 17.2% to 30% were observed immediately after watching the head-mounted display in both groups, but recovered fully within 40 minutes after watching the head-mounted display. There were no significant clinical effects of watching head-mounted display for 30 minutes on the normal adolescent eye. Transient changes in refractive error and binocular alignment were noted, but were not significant. [J Pediatr Ophthalmol Strabismus. 2016;53(4):238-245.]. Copyright 2016, SLACK Incorporated.

Sensorimotor Adaptation Following Exposure to Ambiguous Inertial Motion Cues

NASA Technical Reports Server (NTRS)

Wood, S. J.; Clement, G. R.; Harm, D L.; Rupert, A. H.; Guedry, F. E.; Reschke, M. F.

2005-01-01

The central nervous system must resolve the ambiguity of inertial motion sensory cues in order to derive accurate spatial orientation awareness. Our general hypothesis is that the central nervous system utilizes both multi-sensory integration and frequency segregation as neural strategies to resolve the ambiguity of tilt and translation stimuli. Movement in an altered gravity environment, such as weightlessness without a stable gravity reference, results in new patterns of sensory cues. For example, the semicircular canals, vision and neck proprioception provide information about head tilt on orbit without the normal otolith head-tilt position that is omnipresent on Earth. Adaptive changes in how inertial cues from the otolith system are integrated with other sensory information lead to perceptual and postural disturbances upon return to Earth s gravity. The primary goals of this ground-based research investigation are to explore physiological mechanisms and operational implications of disorientation and tilt-translation disturbances reported by crewmembers during and following re-entry, and to evaluate a tactile prosthesis as a countermeasure for improving control of whole-body orientation during tilt and translation motion.

Sensorimotor Adaptation Following Exposure to Ambiguous Inertial Motion Cues

NASA Technical Reports Server (NTRS)

Wood, S. J.; Clement, G. R.; Harm, D. L.; Rupert, A. H.; Guedry, F. E.; Reschke, M. F.

2005-01-01

The central nervous system must resolve the ambiguity of inertial motion sensory cues in order to derive accurate spatial orientation awareness. Our general hypothesis is that the central nervous system utilizes both multi-sensory integration and frequency segregation as neural strategies to resolve the ambiguity of tilt and translation stimuli. Movement in an altered gravity environment, such as weightlessness without a stable gravity reference, results in new patterns of sensory cues. For example, the semicircular canals, vision and neck proprioception provide information about head tilt on orbit without the normal otolith head-tilt position that is omnipresent on Earth. Adaptive changes in how inertial cues from the otolith system are integrated with other sensory information lead to perceptual and postural disturbances upon return to Earth's gravity. The primary goals of this ground-based research investigation are to explore physiological mechanisms and operational implications of disorientation and tilt-translation disturbances reported by crewmembers during and following re-entry, and to evaluate a tactile prosthesis as a countermeasure for improving control of whole-body orientation during tilt and translation motion.

Implications of Dynamic Pressure Transducer Mounting Variations on Measurements in Pyrotechnic Test Apparatus

NASA Technical Reports Server (NTRS)

Dibbern, Andreas; Crisafulli, Jeffrey; Hagopia, Michael; McDougle, Stephen H.; Saulsberry, Regor L.

2009-01-01

Accurate dynamic pressure measurements are often difficult to make within small pyrotechnic devices, and transducer mounting difficulties can cause data anomalies that lead to erroneous conclusions. Delayed initial pressure response followed by data ringing has been observed when using miniaturized pressure transducer mounting adapters required to interface transducers to small test chambers. This delayed pressure response and ringing, combined with a high data acquisition rate, has complicated data analysis. This paper compares the output signal characteristics from different pressure transducer mounting options, where the passage distance from the transducer face to the pyrotechnic chamber is varied in length and diameter. By analyzing the data and understating the associated system dynamics, a more realistic understanding of the actual dynamic pressure variations is achieved. Three pressure transducer mounting configurations (elongated, standard, and face/flush mount) were simultaneously tested using NASA standard initiators in closed volume pressure bombs. This paper also presents results of these pressure transducer mounting configurations as a result of a larger NASA Engineering and Safety Center pyrovalve test project. Results from these tests indicate the improved performance of using face/flush mounted pressure transducers in this application. This type of mounting improved initial pressure measurement response time by approximately 19 s over standard adapter mounting, eliminating most of the lag time; provided a near step-function type initial pressure increase; and greatly reduced data ringing in high data acquisition rate systems. The paper goes on to discuss other issues associated with the firing and instrumentation that are important for the tester to understand.

Analysis of Radiant Cooling System Configurations Integrated with Cooling Tower for Different Indian Climatic Zones

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mathur, Jyotirmay; Bhandari, Mahabir S; Jain, Robin

Radiant cooling system has proven to be a low energy consumption system for building cooling needs. This study describes the use of cooling tower in radiant cooling system to improve the overall system efficiency. A comprehensive simulation feasibility study of the application of cooling tower in radiant cooling system was performed for the fifteen cities in different climatic zones of India. It was found that in summer, the wet bulb temperature (WBT) of the different climatic zones except warm-humid is suitable for the integration of cooling tower with radiant cooling system. In these climates, cooling tower can provide on averagemore » 24 C to 27 C water In order to achieve the energy saving potential, three different configurations of radiant cooling system have been compared in terms of energy consumption. The different configurations of the radiant cooling system integrated with cooling tower are: (1) provide chilled water to the floor, wall and ceiling mounted tubular installation. (2) provide chilled water to the wall and ceiling mounted tabular installation. In this arrangement a separate chiller has also been used to provide chilled water at 16 C to the floor mounted tubular installation. (3) provide chilled water to the wall mounted tabular installation and a separate chiller is used to provide chilled water at 16 C to the floor and ceiling mounted tabular installation. A dedicated outdoor air system is also coupled for dehumidification and ventilation in all three configurations. A conventional all-air system was simulated as a baseline to compare these configurations for assessing the energy saving potential.« less

Social Vision: Functional Forecasting and the Integration of Compound Social Cues

PubMed Central

Adams, Reginald B.; Kveraga, Kestutis

2017-01-01

For decades the study of social perception was largely compartmentalized by type of social cue: race, gender, emotion, eye gaze, body language, facial expression etc. This was partly due to good scientific practice (e.g., controlling for extraneous variability), and partly due to assumptions that each type of social cue was functionally distinct from others. Herein, we present a functional forecast approach to understanding compound social cue processing that emphasizes the importance of shared social affordances across various cues (see too Adams, Franklin, Nelson, & Stevenson, 2010; Adams & Nelson, 2011; Weisbuch & Adams, 2012). We review the traditional theories of emotion and face processing that argued for dissociable and noninteracting pathways (e.g., for specific emotional expressions, gaze, identity cues), as well as more recent evidence for combinatorial processing of social cues. We argue here that early, and presumably reflexive, visual integration of such cues is necessary for adaptive behavioral responding to others. In support of this claim, we review contemporary work that reveals a flexible visual system, one that readily incorporates meaningful contextual influences in even nonsocial visual processing, thereby establishing the functional and neuroanatomical bases necessary for compound social cue integration. Finally, we explicate three likely mechanisms driving such integration. Together, this work implicates a role for cognitive penetrability in visual perceptual abilities that have often been (and in some cases still are) ascribed to direct encapsulated perceptual processes. PMID:29242738

Test Operations Procedure (TOP) 6-3-044. Optical Transfer Function

DTIC Science & Technology

2009-07-27

Mounting Fixtures As required Alignment Periscope See section 4.1.6 TOP 6-3-040 27 July 2009 3 3. REQUIRED TEST CONDITIONS. 3.1 Pre-test...carefully selected. The stabilized cast iron lathe bed type, typically 2-3 m long, provides adequate support for mounting the various assemblies...combined size and weight of some vehicle mounted sights, a special mounting fixture , perhaps including a periscopic system may be required. It is

Investigation of correlation between full-scale and fifth-scale wind tunnel tests of a Bell helicopter Textron Model 222

NASA Technical Reports Server (NTRS)

Squires, P. K.

1982-01-01

Reasons for lack of correlation between data from a fifth-scale wind tunnel test of the Bell Helicopter Textron Model 222 and a full-scale test of the model 222 prototype in the NASA Ames 40-by 80-foot tunnel were investigated. This investigation centered around a carefully designed fifth-scale wind tunnel test of an accurately contoured model of the Model 222 prototype mounted on a replica of the full-scale mounting system. The improvement in correlation for drag characteristics in pitch and yaw with the fifth-scale model mounted on the replica system is shown. Interference between the model and mounting system was identified as a significant effect and was concluded to be a primary cause of the lack of correlation in the earlier tests.

Cocaine cues drive opposing context-dependent shifts in reward processing and emotional state.

PubMed

Wheeler, Robert A; Aragona, Brandon J; Fuhrmann, Katherine A; Jones, Joshua L; Day, Jeremy J; Cacciapaglia, Fabio; Wightman, R Mark; Carelli, Regina M

2011-06-01

Prominent neurobiological theories of addiction posit a central role for aberrant mesolimbic dopamine release but disagree as to whether repeated drug experience blunts or enhances this system. Although drug withdrawal diminishes dopamine release, drug sensitization augments mesolimbic function, and both processes have been linked to drug seeking. One possibility is that the dopamine system can rapidly switch from dampened to enhanced release depending on the specific drug-predictive environment. To test this, we examined dopamine release when cues signaled delayed cocaine delivery versus imminent cocaine self-administration. Fast-scan cyclic voltammetry was used to examine real-time dopamine release while simultaneously monitoring behavioral indexes of aversion as rats experienced a sweet taste cue that predicted delayed cocaine availability and during self-administration. Furthermore, the impact of cues signaling delayed drug availability on intracranial self-stimulation, a broad measure of reward function, was assessed. We observed decreased mesolimbic dopamine concentrations, decreased reward sensitivity, and negative affect in response to the cocaine-predictive taste cue that signaled delayed cocaine availability. Importantly, dopamine concentration rapidly switched to elevated levels to cues signaling imminent cocaine delivery in the subsequent self-administration session. These findings show rapid, bivalent contextual control over brain reward processing, affect, and motivated behavior and have implications for mechanisms mediating substance abuse. Copyright © 2011 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

The Effects of Pharmacological Opioid Blockade on Neural Measures of Drug Cue-Reactivity in Humans

PubMed Central

Courtney, Kelly E; Ghahremani, Dara G; Ray, Lara A

2016-01-01

Interactions between dopaminergic and opioidergic systems have been implicated in the reinforcing properties of drugs of abuse. The present study investigated the effects of opioid blockade, via naltrexone, on functional magnetic resonance imaging (fMRI) measures during methamphetamine cue-reactivity to elucidate the role of endogenous opioids in the neural systems underlying drug craving. To investigate this question, non-treatment seeking individuals with methamphetamine use disorder (N=23; 74% male, mean age=34.70 (SD=8.95)) were recruited for a randomized, placebo controlled, within-subject design and underwent a visual methamphetamine cue-reactivity task during two blood-oxygen-level dependent (BOLD) fMRI sessions following 3 days of naltrexone (50 mg) and matched time for placebo. fMRI analyses tested naltrexone-induced differences in BOLD activation and functional connectivity during cue processing. The results showed that naltrexone administration reduced cue-reactivity in sensorimotor regions and related to altered functional connectivity of dorsal striatum, ventral tegmental area, and precuneus with frontal, visual, sensory, and motor-related regions. Naltrexone also weakened the associations between subjective craving and precuneus functional connectivity with sensorimotor regions and strengthened the associations between subjective craving and dorsal striatum and precuneus connectivity with frontal regions. In conclusion, this study provides the first evidence that opioidergic blockade alters neural responses to drug cues in humans with methamphetamine addiction and suggests that naltrexone may be reducing drug cue salience by decreasing the involvement of sensorimotor regions and by engaging greater frontal regulation over salience attribution. PMID:27312405

Dynamic Vibrotactile Signals for Forward Collision Avoidance Warning Systems

PubMed Central

Meng, Fanxing; Gray, Rob; Ho, Cristy; Ahtamad, Mujthaba

2015-01-01

Objective: Four experiments were conducted in order to assess the effectiveness of dynamic vibrotactile collision-warning signals in potentially enhancing safe driving. Background: Auditory neuroscience research has demonstrated that auditory signals that move toward a person are more salient than those that move away. If this looming effect were found to extend to the tactile modality, then it could be utilized in the context of in-car warning signal design. Method: The effectiveness of various vibrotactile warning signals was assessed using a simulated car-following task. The vibrotactile warning signals consisted of dynamic toward-/away-from-torso cues (Experiment 1), dynamic versus static vibrotactile cues (Experiment 2), looming-intensity- and constant-intensity-toward-torso cues (Experiment 3), and static cues presented on the hands or on the waist, having either a low or high vibration intensity (Experiment 4). Results: Braking reaction times (BRTs) were significantly faster for toward-torso as compared to away-from-torso cues (Experiments 1 and 2) and static cues (Experiment 2). This difference could not have been attributed to differential responses to signals delivered to different body parts (i.e., the waist vs. hands; Experiment 4). Embedding a looming-intensity signal into the toward-torso signal did not result in any additional BRT benefits (Experiment 3). Conclusion: Dynamic vibrotactile cues that feel as though they are approaching the torso can be used to communicate information concerning external events, resulting in a significantly faster reaction time to potential collisions. Application: Dynamic vibrotactile warning signals that move toward the body offer great potential for the design of future in-car collision-warning system. PMID:25850161

Aversive Stimuli Differentially Modulate Real-Time Dopamine Transmission Dynamics within the Nucleus Accumbens Core and Shell

PubMed Central

Badrinarayan, Aneesha; Wescott, Seth A.; Vander Weele, Caitlin M.; Saunders, Benjamin T.; Couturier, Brenann E.; Maren, Stephen

2012-01-01

Although fear directs adaptive behavioral responses, how aversive cues recruit motivational neural circuitry is poorly understood. Specifically, while it is known that dopamine (DA) transmission within the nucleus accumbens (NAc) is imperative for mediating appetitive motivated behaviors, its role in aversive behavior is controversial. It has been proposed that divergent phasic DA transmission following aversive events may correspond to segregated mesolimbic dopamine pathways; however, this prediction has never been tested. Here, we used fast-scan cyclic voltammetry to examine real-time DA transmission within NAc core and shell projection systems in response to a fear-evoking cue. In male Sprague Dawley rats, we first demonstrate that a fear cue results in decreased DA transmission within the NAc core, but increased transmission within the NAc shell. We examined whether these changes in DA transmission could be attributed to modulation of phasic transmission evoked by cue presentation. We found that cue presentation decreased the probability of phasic DA release in the core, while the same cue enhanced the amplitude of release events in the NAc shell. We further characterized the relationship between freezing and both changes in DA as well as local pH. Although we found that both analytes were significantly correlated with freezing in the NAc across the session, changes in DA were not strictly associated with freezing while basic pH shifts in the core more consistently followed behavioral expression. Together, these results provide the first real-time neurochemical evidence that aversive cues differentially modulate distinct DA projection systems. PMID:23136417

Contextual Cueing Effect in Spatial Layout Defined by Binocular Disparity

PubMed Central

Zhao, Guang; Zhuang, Qian; Ma, Jie; Tu, Shen; Liu, Qiang; Sun, Hong-jin

2017-01-01

Repeated visual context induces higher search efficiency, revealing a contextual cueing effect, which depends on the association between the target and its visual context. In this study, participants performed a visual search task where search items were presented with depth information defined by binocular disparity. When the 3-dimensional (3D) configurations were repeated over blocks, the contextual cueing effect was obtained (Experiment 1). When depth information was in chaos over repeated configurations, visual search was not facilitated and the contextual cueing effect largely crippled (Experiment 2). However, when we made the search items within a tiny random displacement in the 2-dimentional (2D) plane but maintained the depth information constant, the contextual cueing was preserved (Experiment 3). We concluded that the contextual cueing effect was robust in the context provided by 3D space with stereoscopic information, and more importantly, the visual system prioritized stereoscopic information in learning of spatial information when depth information was available. PMID:28912739

Effect of motion cues during complex curved approach and landing tasks: A piloted simulation study

NASA Technical Reports Server (NTRS)

Scanlon, Charles H.

1987-01-01

A piloted simulation study was conducted to examine the effect of motion cues using a high fidelity simulation of commercial aircraft during the performance of complex approach and landing tasks in the Microwave Landing System (MLS) signal environment. The data from these tests indicate that in a high complexity MLS approach task with moderate turbulence and wind, the pilot uses motion cues to improve path tracking performance. No significant differences in tracking accuracy were noted for the low and medium complexity tasks, regardless of the presence of motion cues. Higher control input rates were measured for all tasks when motion was used. Pilot eye scan, as measured by instrument dwell time, was faster when motion cues were used regardless of the complexity of the approach tasks. Pilot comments indicated a preference for motion. With motion cues, pilots appeared to work harder in all levels of task complexity and to improve tracking performance in the most complex approach task.

Motion Cueing Algorithm Development: New Motion Cueing Program Implementation and Tuning

NASA Technical Reports Server (NTRS)

Houck, Jacob A. (Technical Monitor); Telban, Robert J.; Cardullo, Frank M.; Kelly, Lon C.

2005-01-01

A computer program has been developed for the purpose of driving the NASA Langley Research Center Visual Motion Simulator (VMS). This program includes two new motion cueing algorithms, the optimal algorithm and the nonlinear algorithm. A general description of the program is given along with a description and flowcharts for each cueing algorithm, and also descriptions and flowcharts for subroutines used with the algorithms. Common block variable listings and a program listing are also provided. The new cueing algorithms have a nonlinear gain algorithm implemented that scales each aircraft degree-of-freedom input with a third-order polynomial. A description of the nonlinear gain algorithm is given along with past tuning experience and procedures for tuning the gain coefficient sets for each degree-of-freedom to produce the desired piloted performance. This algorithm tuning will be needed when the nonlinear motion cueing algorithm is implemented on a new motion system in the Cockpit Motion Facility (CMF) at the NASA Langley Research Center.

Contextual Cueing Effect in Spatial Layout Defined by Binocular Disparity.

PubMed

Zhao, Guang; Zhuang, Qian; Ma, Jie; Tu, Shen; Liu, Qiang; Sun, Hong-Jin

2017-01-01

Repeated visual context induces higher search efficiency, revealing a contextual cueing effect, which depends on the association between the target and its visual context. In this study, participants performed a visual search task where search items were presented with depth information defined by binocular disparity. When the 3-dimensional (3D) configurations were repeated over blocks, the contextual cueing effect was obtained (Experiment 1). When depth information was in chaos over repeated configurations, visual search was not facilitated and the contextual cueing effect largely crippled (Experiment 2). However, when we made the search items within a tiny random displacement in the 2-dimentional (2D) plane but maintained the depth information constant, the contextual cueing was preserved (Experiment 3). We concluded that the contextual cueing effect was robust in the context provided by 3D space with stereoscopic information, and more importantly, the visual system prioritized stereoscopic information in learning of spatial information when depth information was available.

An investigation of motion base cueing and G-seat cueing on pilot performance in a simulator

NASA Technical Reports Server (NTRS)

Mckissick, B. T.; Ashworth, B. R.; Parrish, R. V.

1983-01-01

The effect of G-seat cueing (GSC) and motion-base cueing (MBC) on performance of a pursuit-tracking task is studied using the visual motion simulator (VMS) at Langley Research Center. The G-seat, the six-degree-of-freedom synergistic platform motion system, the visual display, the cockpit hardware, and the F-16 aircraft mathematical model are characterized. Each of 8 active F-15 pilots performed the 2-min-43-sec task 10 times for each experimental mode: no cue, GSC, MBC, and GSC + MBC; the results were analyzed statistically in terms of the RMS values of vertical and lateral tracking error. It is shown that lateral error is significantly reduced by either GSC or MBC, and that the combination of cues produces a further, significant decrease. Vertical error is significantly decreased by GSC with or without MBC, whereas MBC effects vary for different pilots. The pattern of these findings is roughly duplicated in measurements of stick force applied for roll and pitch correction.

Performance effects of mounting a helmet-mounted display on the ANVIS mount of the HGU-56P helmet

NASA Astrophysics Data System (ADS)

Harding, Thomas H.; Martin, John S.; Rash, Clarence E.

2006-05-01

The U.S. Army, under the auspices of the Air Warrior Product Office, is developing a modular helmet-mounted display (HMD) for four aircraft series within its helicopter fleet. A design consideration is mounting the HMDs to the HGU- 56P Aviator's Night Vision Imaging System (ANVIS) mount. This particular mount is being considered, presumably due to its inherent cost savings, as the mount is already part of the helmet. Mounting the HMD in this position may have consequences for the daylight performance of these HMDs, as well as increasing the forward weight of the HMD. The latter would have consequences for helmet weight and center-of-mass biodynamic issues. Calculations were made of the increased luminance needed as a consequence of mounting the HMD in front of an HGU-56P tinted visor as opposed to mounting it behind the visor. By mounting in front of the helmet's visor, the HMD's light output will be filtered as light coming from the outside world. Special consideration then would have to be given to the HMD's light source selection process, as not to select a source that would differentially reduce luminance by a mounted visor (e.g., laser protection visors) compared to the ambient light in the aviator's field-of-view.

A Single Serine Residue Determines Selectivity to Monovalent Metal Ions in Metalloregulators of the MerR Family

PubMed Central

Ibáñez, María M.

2015-01-01

ABSTRACT MerR metalloregulators alleviate toxicity caused by an excess of metal ions, such as copper, zinc, mercury, lead, cadmium, silver, or gold, by triggering the expression of specific efflux or detoxification systems upon metal detection. The sensor protein binds the inducer metal ion by using two conserved cysteine residues at the C-terminal metal-binding loop (MBL). Divalent metal ion sensors, such as MerR and ZntR, require a third cysteine residue, located at the beginning of the dimerization (α5) helix, for metal coordination, while monovalent metal ion sensors, such as CueR and GolS, have a serine residue at this position. This serine residue was proposed to provide hydrophobic and steric restrictions to privilege the binding of monovalent metal ions. Here we show that the presence of alanine at this position does not modify the activation pattern of monovalent metal sensors. In contrast, GolS or CueR mutant sensors with a substitution of cysteine for the serine residue respond to monovalent metal ions or Hg(II) with high sensitivities. Furthermore, in a mutant deleted of the Zn(II) exporter ZntA, they also trigger the expression of their target genes in response to either Zn(II), Cd(II), Pb(II), or Co(II). IMPORTANCE Specificity in a stressor's recognition is essential for mounting an appropriate response. MerR metalloregulators trigger the expression of specific resistance systems upon detection of heavy metal ions. Two groups of these metalloregulators can be distinguished, recognizing either +1 or +2 metal ions, depending on the presence of a conserved serine in the former or a cysteine in the latter. Here we demonstrate that the serine residue in monovalent metal ion sensors excludes divalent metal ion detection, as its replacement by cysteine renders a pan-metal ion sensor. Our results indicate that the spectrum of signals detected by these sensors is determined not only by the metal-binding ligand availability but also by the metal-binding cavity flexibility. PMID:25691529

Solar energy system installed at Mount Rushmore National Visitor Center in Keystone, South Dakota

NASA Technical Reports Server (NTRS)

1979-01-01

The design and installation of the solar energy system installed at the Mount Rushmore Visitor Center is described. The system was designed to furnish about 45 percent of the heating for the total facility and about 53 percent partial cooling for the 2000 square foot observatory.

Ground sprayer designs for forestry applications

Treesearch

James H. Miller; Qiu Zhongze; D.L. Sirois

1985-01-01

Three herbicide spraying systems were designed, constructed, and field tested in cooperation with the-USDA Forest Service,.Georgia Forestry Commission, and Scott Paper Company. One system was designed to mount on wildland tree planting machines for applying banded treatments for herbaceous weed control. This system consisted of a top mounted 50-gal tank and a small...

The Effects of Content-Area Writing Patterns Upon Cue System Utilization by Second-Grade, Ninth-Grade, and Mature Adult Readers.

ERIC Educational Resources Information Center

Stansell, John C.; And Others

Studies were conducted to investigate cue system utilization by three groups of readers--six second graders, six ninth graders, and four adults past the age of sixty who were rated as mature readers. The second graders read materials that varied according to organizational structure, while the other groups read materials that differed in the…

Processing of lexical stress cues by young children.

PubMed

Quam, Carolyn; Swingley, Daniel

2014-07-01

Although infants learn an impressive amount about their native-language phonological system by the end of the first year of life, after the first year children still have much to learn about how acoustic dimensions cue linguistic categories in fluent speech. The current study investigated what children have learned about how the acoustic dimension of pitch indicates the location of the stressed syllable in familiar words. Preschoolers (2.5- to 5-year-olds) and adults were tested on their ability to use lexical-stress cues to identify familiar words. Both age groups saw pictures of a bunny and a banana and heard versions of "bunny" and "banana" in which stress either was indicated normally with convergent cues (pitch, duration, amplitude, and vowel quality) or was manipulated such that only pitch differentiated the words' initial syllables. Adults (n=48) used both the convergent cues and the isolated pitch cue to identify the target words as they unfolded. Children (n=206) used the convergent stress cues but not pitch alone in identifying words. We discuss potential reasons for children's difficulty in exploiting isolated pitch cues to stress despite children's early sensitivity to pitch in language. These findings contribute to a view in which phonological development progresses toward the adult state well past infancy. Copyright © 2014 Elsevier Inc. All rights reserved.

Effects of cues in a binary categorization task on dual-task performance, mental workload, and effort.

PubMed

Botzer, Assaf; Meyer, Joachim; Parmet, Yisrael

2016-09-01

Binary cues help operators perform binary categorization tasks, such as monitoring for system failures. They may also allow them to attend to other tasks they concurrently perform. If the time saved by using cues is allocated to other concurrent tasks, users' overall effort may remain unchanged. In 2 experiments, participants performed a simulated quality control task, together with a tracking task. In half the experimental blocks cues were available, and participants could use them in their decisions about the quality of products (intact or faulty). In Experiment 1, the difficulty of tracking was constant, while in Experiment 2, tracking difficulty differed in the 2 halves of the experiment. In both experiments, participants reported on the NASA Task Load Index that cues improved their performance and reduced their frustration. Consequently, their overall score on mental workload (MWL) was lower with cues. They also reported, however, that cues did not reduce their effort. We conclude that cues and other forms of automation may support task performance and reduce overall MWL, but this will not necessarily mean that users will work less hard. Thus, effort and overall MWL should be evaluated separately, if one wants to obtain a full picture of the effects of automation. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Mechanisms underlying the control of responses to predator odours in aquatic prey.

PubMed

Mitchell, Matthew D; Bairos-Novak, Kevin R; Ferrari, Maud C O

2017-06-01

In aquatic systems, chemical cues are a major source of information through which animals are able to assess the current state of their environment to gain information about local predation risk. Prey use chemicals released by predators (including cues from a predator's diet) and other prey (such as alarm cues and disturbance cues) to mediate a range of behavioural, morphological and life-history antipredator defences. Despite the wealth of knowledge on the ecology of antipredator defences, we know surprisingly little about the physiological mechanisms that control the expression of these defensive traits. Here, we summarise the current literature on the mechanisms known to specifically mediate responses to predator odours, including dietary cues. Interestingly, these studies suggest that independent pathways may control predator-specific responses, highlighting the need for greater focus on predator-derived cues when looking at the mechanistic control of responses. Thus, we urge researchers to tease apart the effects of predator-specific cues (i.e. chemicals representing a predator's identity) from those of diet-mediated cues (i.e. chemicals released from a predator's diet), which are known to mediate different ecological endpoints. Finally, we suggest some key areas of research that would greatly benefit from a more mechanistic approach. © 2017. Published by The Company of Biologists Ltd.

Processing of Lexical-Stress Cues by Young Children

PubMed Central

Quam, Carolyn; Swingley, Daniel

2014-01-01

Though infants learn an impressive amount about their native-language phonological system by the end of the first year of life, after the first year children still have much to learn about how acoustic dimensions cue linguistic categories in fluent speech. The present study investigates what children have learned about how the acoustic dimension of pitch indicates the location of the stressed syllable in familiar words. Preschoolers (2.5–5 years) and adults were tested on their ability to use lexical-stress cues to identify familiar words. Both age groups saw pictures of a bunny and a banana, and heard versions of “bunny” and “banana” in which stress was either indicated normally with convergent cues (pitch, duration, amplitude, and vowel quality), or was manipulated such that only pitch differentiated the words’ initial syllables. Adults (n=48) used both the convergent cues, and the isolated pitch cue, to identify the target words as they unfolded. Children (n=206) used the convergent stress cues, but not pitch alone, in identifying words. We discuss potential reasons for children’s difficulty exploiting isolated pitch cues to stress, despite children’s early sensitivity to pitch in language (e.g., Fernald, 1992). These findings contribute to a view in which phonological development progresses toward the adult state well past infancy. PMID:24705094

Impaired movement timing in neurological disorders: rehabilitation and treatment strategies.

PubMed

Hove, Michael J; Keller, Peter E

2015-03-01

Timing abnormalities have been reported in many neurological disorders, including Parkinson's disease (PD). In PD, motor-timing impairments are especially debilitating in gait. Despite impaired audiomotor synchronization, PD patients' gait improves when they walk with an auditory metronome or with music. Building on that research, we make recommendations for optimizing sensory cues to improve the efficacy of rhythmic cuing in gait rehabilitation. Adaptive rhythmic metronomes (that synchronize with the patient's walking) might be especially effective. In a recent study we showed that adaptive metronomes synchronized consistently with PD patients' footsteps without requiring attention; this improved stability and reinstated healthy gait dynamics. Other strategies could help optimize sensory cues for gait rehabilitation. Groove music strongly engages the motor system and induces movement; bass-frequency tones are associated with movement and provide strong timing cues. Thus, groove and bass-frequency pulses could deliver potent rhythmic cues. These strategies capitalize on the close neural connections between auditory and motor networks; and auditory cues are typically preferred. However, moving visual cues greatly improve visuomotor synchronization and could warrant examination in gait rehabilitation. Together, a treatment approach that employs groove, auditory, bass-frequency, and adaptive (GABA) cues could help optimize rhythmic sensory cues for treating motor and timing deficits. © 2014 New York Academy of Sciences.

Acetylcholine Release in Prefrontal Cortex Promotes Gamma Oscillations and Theta-Gamma Coupling during Cue Detection.

PubMed

Howe, William M; Gritton, Howard J; Lusk, Nicholas A; Roberts, Erik A; Hetrick, Vaughn L; Berke, Joshua D; Sarter, Martin

2017-03-22

The capacity for using external cues to guide behavior ("cue detection") constitutes an essential aspect of attention and goal-directed behavior. The cortical cholinergic input system, via phasic increases in prefrontal acetylcholine release, plays an essential role in attention by mediating such cue detection. However, the relationship between cholinergic signaling during cue detection and neural activity dynamics in prefrontal networks remains unclear. Here we combined subsecond measures of cholinergic signaling, neurophysiological recordings, and cholinergic receptor blockade to delineate the cholinergic contributions to prefrontal oscillations during cue detection in rats. We first confirmed that detected cues evoke phasic acetylcholine release. These cholinergic signals were coincident with increased neuronal synchrony across several frequency bands and the emergence of theta-gamma coupling. Muscarinic and nicotinic cholinergic receptors both contributed specifically to gamma synchrony evoked by detected cues, but the effects of blocking the two receptor subtypes were dissociable. Blocking nicotinic receptors primarily attenuated high-gamma oscillations occurring during the earliest phases of the cue detection process, while muscarinic (M1) receptor activity was preferentially involved in the transition from high to low gamma power that followed and corresponded to the mobilization of networks involved in cue-guided decision making. Detected cues also promoted coupling between gamma and theta oscillations, and both nicotinic and muscarinic receptor activity contributed to this process. These results indicate that acetylcholine release coordinates neural oscillations during the process of cue detection. SIGNIFICANCE STATEMENT The capacity of learned cues to direct attention and guide responding ("cue detection") is a key component of goal-directed behavior. Rhythmic neural activity and increases in acetylcholine release in the prefrontal cortex contribute to this process; however, the relationship between these neuronal mechanisms is not well understood. Using a combination of in vivo neurochemistry, neurophysiology, and pharmacological methods, we demonstrate that cue-evoked acetylcholine release, through distinct actions at both nicotinic and muscarinic receptors, triggers a procession of neural oscillations that map onto the multiple stages of cue detection. Our data offer new insights into cholinergic function by revealing the temporally orchestrated changes in prefrontal network synchrony modulated by acetylcholine release during cue detection. Copyright © 2017 the authors 0270-6474/17/373215-16$15.00/0.

Method of vibration isolating an aircraft engine

NASA Technical Reports Server (NTRS)

Bender, Stanley I. (Inventor); Butler, Lawrence (Inventor); Dawes, Peter W. (Inventor)

1991-01-01

A method for coupling an engine to a support frame for mounting to a fuselage of an aircraft using a three point vibration isolating mounting system in which the load reactive forces at each mounting point are statically and dynamically determined. A first vibration isolating mount pivotably couples a first end of an elongated support beam to a stator portion of an engine with the pivoting action of the vibration mount being oriented such that it is pivotable about a line parallel to a center line of the engine. An aft end of the supporting frame is coupled to the engine through an additional pair of vibration isolating mounts with the mounts being oriented such that they are pivotable about a circumference of the engine. The aft mounts are symmetrically spaced to each side of the supporting frame by 45 degrees. The relative orientation between the front mount and the pair of rear mounts is such that only the rear mounts provide load reactive forces parallel to the engine center line, in support of the engine to the aircraft against thrust forces. The forward mount is oriented so as to provide only radial forces to the engine and some lifting forces to maintain the engine in position adjacent a fuselage. Since each mount is connected to provide specific forces to support the engine, forces required of each mount are statically and dynamically determinable.

Diverse Roads to Relapse: A Discriminative Cue Signaling Cocaine Availability Is More Effective in Renewing Cocaine Seeking in Goal Trackers Than Sign Trackers and Depends on Basal Forebrain Cholinergic Activity.

PubMed

Pitchers, Kyle K; Phillips, Kyra B; Jones, Jonte L; Robinson, Terry E; Sarter, Martin

2017-07-26

Stimuli associated with taking drugs are notorious instigators of relapse. There is, however, considerable variation in the motivational properties of such stimuli, both as a function of the individual and the nature of the stimulus. The behavior of some individuals (sign trackers, STs) is especially influenced by cues paired with reward delivery, perhaps because they are prone to process information via dopamine-dependent, cue-driven, incentive salience systems. Other individuals (goal trackers, GTs) are better able to incorporate higher-order contextual information, perhaps because of better executive/attentional control over behavior, which requires frontal cortical cholinergic activity. We hypothesized, therefore, that a cue that "sets the occasion" for drug taking (a discriminative stimulus, DS) would reinstate cocaine seeking more readily in GTs than STs and that this would require intact cholinergic neurotransmission. To test this, male STs and GTs were trained to self-administer cocaine using an intermittent access schedule with periods of cocaine availability and unavailability signaled by a DS + and a DS - , respectively. Thereafter, half of the rats received an immunotoxic lesion that destroyed 40-50% of basal forebrain cholinergic neurons and later, after extinction training, were tested for the ability of noncontingent presentations of the DS + to reinstate cocaine seeking behavior. The DS + was much more effective in reinstating cocaine seeking in GTs than STs and this effect was abolished by cholinergic losses despite the fact that all rats continued to orient to the DS + We conclude that vulnerability to relapse involves interactions between individual cognitive-motivational biases and the form of the drug cue encountered. SIGNIFICANCE STATEMENT The most predictable outcome of a diagnosis of addiction is a high chance for relapse. When addicts encounter cues previously associated with drug, their attention may be unduly attracted to such cues and these cues can evoke motivational states that instigate and maintain drug-seeking behavior. Although sign-tracking rats were previously demonstrated to exhibit greater relapse vulnerability to Pavlovian drug cues paired with drug delivery, here, we demonstrate that their counterparts, the goal trackers, are more vulnerable if the drug cue acts to signal drug availability and that the forebrain cholinergic system mediates such vulnerability. Given the importance of contextual cues for triggering relapse and the human cognitive-cholinergic capacity for the processing of such cues, goal trackers model essential aspects of relapse vulnerability. Copyright © 2017 the authors 0270-6474/17/377198-11$15.00/0.

Estimating the relative weights of visual and auditory tau versus heuristic-based cues for time-to-contact judgments in realistic, familiar scenes by older and younger adults.

PubMed

Keshavarz, Behrang; Campos, Jennifer L; DeLucia, Patricia R; Oberfeld, Daniel

2017-04-01

Estimating time to contact (TTC) involves multiple sensory systems, including vision and audition. Previous findings suggested that the ratio of an object's instantaneous optical size/sound intensity to its instantaneous rate of change in optical size/sound intensity (τ) drives TTC judgments. Other evidence has shown that heuristic-based cues are used, including final optical size or final sound pressure level. Most previous studies have used decontextualized and unfamiliar stimuli (e.g., geometric shapes on a blank background). Here we evaluated TTC estimates by using a traffic scene with an approaching vehicle to evaluate the weights of visual and auditory TTC cues under more realistic conditions. Younger (18-39 years) and older (65+ years) participants made TTC estimates in three sensory conditions: visual-only, auditory-only, and audio-visual. Stimuli were presented within an immersive virtual-reality environment, and cue weights were calculated for both visual cues (e.g., visual τ, final optical size) and auditory cues (e.g., auditory τ, final sound pressure level). The results demonstrated the use of visual τ as well as heuristic cues in the visual-only condition. TTC estimates in the auditory-only condition, however, were primarily based on an auditory heuristic cue (final sound pressure level), rather than on auditory τ. In the audio-visual condition, the visual cues dominated overall, with the highest weight being assigned to visual τ by younger adults, and a more equal weighting of visual τ and heuristic cues in older adults. Overall, better characterizing the effects of combined sensory inputs, stimulus characteristics, and age on the cues used to estimate TTC will provide important insights into how these factors may affect everyday behavior.

Aversive and appetitive events evoke the release of corticotropin-releasing hormone and bombesin-like peptides at the central nucleus of the amygdala.

PubMed

Merali, Z; McIntosh, J; Kent, P; Michaud, D; Anisman, H

1998-06-15

There is wide agreement that corticotropin-releasing hormone (CRH) systems within the brain are activated by stressful stimuli. There is also mounting evidence for the role of bombesin (BN)-like peptides in the mediation of the stress response. To date, however, the extent to which other stimuli increase the activity of these peptidergic systems has received little attention. In the present investigation we validated and used in vivo microdialysis sampling followed by ex vivo radioimmunoassays to monitor the release of CRH and BN-like peptides during appetitive (food intake) and stressful (restraint) events. It is demonstrated for the first time that the in vivo release of CRH and BN-like peptides at the central nucleus of the amygdala was markedly increased by both stressor exposure and food ingestion. In fact, the meal-elicited rise of CRH release was as great as that associated with 20 min of restraint stress. Paralleling these findings, circulating ACTH and corticosterone levels were also increased in response to both food intake and restraint. Contrary to the current views, these results indicate that either food ingestion is interpreted as a "stressful" event by certain neural circuits involving the central amygdala or that the CRH- and BN-related peptidergic systems may serve a much broader role than previously envisioned. Rather than evoking feelings of fear and anxiety, these systems may serve to draw attention to events or cues of biological significance, such as those associated with food availability as well as those posing a threat to survival.

Primary display latency criteria based on flying qualities and performance data

NASA Technical Reports Server (NTRS)

Funk, John D., Jr.; Beck, Corin P.; Johns, John B.

1993-01-01

With a pilots' increasing use of visual cue augmentation, much requiring extensive pre-processing, there is a need to establish criteria for new avionics/display design. The timeliness and synchronization of the augmented cues is vital to ensure the performance quality required for precision mission task elements (MTEs) where augmented cues are the primary source of information to the pilot. Processing delays incurred while transforming sensor-supplied flight information into visual cues are unavoidable. Relationships between maximum control system delays and associated flying qualities levels are documented in MIL-F-83300 and MIL-F-8785. While cues representing aircraft status may be just as vital to the pilot as prompt control response for operations in instrument meteorological conditions, presently, there are no specification requirements on avionics system latency. To produce data relating avionics system latency to degradations in flying qualities, the Navy conducted two simulation investigations. During the investigations, flying qualities and performance data were recorded as simulated avionics system latency was varied. Correlated results of the investigation indicates that there is a detrimental impact of latency on flying qualities. Analysis of these results and consideration of key factors influencing their application indicate that: (1) Task performance degrades and pilot workload increases as latency is increased. Inconsistency in task performance increases as latency increases. (2) Latency reduces the probability of achieving Level 1 handling qualities with avionics system latency as low as 70 ms. (3) The data suggest that the achievement of desired performance will be ensured only at display latency values below 120 ms. (4) These data also suggest that avoidance of inadequate performance will be ensured only at display latency values below 150 ms.

Field-trip guide to Mount Hood, Oregon, highlighting eruptive history and hazards

USGS Publications Warehouse

Scott, William E.; Gardner, Cynthia A.

2017-06-22

This guidebook describes stops of interest for a geological field trip around Mount Hood volcano. It was developed for the 2017 International Association of Volcanology and Chemistry of the Earth’s Interior (IAVCEI) Scientific Assembly in Portland, Oregon. The intent of this guidebook and accompanying contributions is to provide an overview of Mount Hood, including its chief geologic processes, magmatic system, eruptive history, local tectonics, and hazards, by visiting a variety of readily accessible localities. We also describe coeval, largely monogenetic, volcanoes in the region. Accompanying the field-trip guidebook are separately authored contributions that discuss in detail the Mount Hood magmatic system and its products and behavior (Kent and Koleszar, this volume); Mount Hood earthquakes and their relation to regional tectonics and the volcanic system (Thelen and Moran, this volume); and young surface faults cutting the broader Mount Hood area whose extent has come to light after acquisition of regional light detection and ranging coverage (Madin and others, this volume).The trip makes an approximately 175-mile (280-kilometer) clockwise loop around Mount Hood, starting and ending in Portland. The route heads east on Interstate 84 through the Columbia River Gorge National Scenic Area. The guidebook points out only a few conspicuous features of note in the gorge, but many other guides to the gorge are available. The route continues south on the Mount Hood National Scenic Byway on Oregon Route 35 following Hood River, and returns to Portland on U.S. Highway 26 following Sandy River. The route traverses rocks as old as the early Miocene Eagle Creek Formation and overlying Columbia River Basalt Group of middle Miocene age, but chiefly lava flows and clastic products of arc volcanism of late Miocene to Holocene age.

Radiometric, Spectral and Effectiveness Equipment

DTIC Science & Technology

1993-09-24

modified Contraves Kineto Tracking Mount (KTM) Model 443. The KTM is a self-contained trailer and mount. The trailer is a four wheel duel-axle bed with...measurement system also uses the Contraves (KTM) Model 433. The KTM is a self-contained trailer and mount. The trailer is a four wheel duel-axle bed with

Performance Analysis of AN Engine Mount Featuring ER Fluids and Piezoactuators

NASA Astrophysics Data System (ADS)

Choi, S. H.; Choi, Y. T.; Choi, S. B.; Cheong, C. C.

Conventional rubber mounts and various types of passive or semi-active hydraulic engine mounts for a passenger vehicle have their own functional aims on the limited frequency band in the broad engine operating frequency range. In order to achieve high system performance over all frequency ranges of the engine operation, a new type of engine mount featuring electro-rheological(ER) fluids and piezoactuators is proposed in this study. A mathematical model of the proposed engine mount is derived using the bond graph method which is inherently adequate to model the interconnected hydromechanical system. In the low frequency domain, the ER fluid is activated upon imposing an electric field for vibration isolation while the piezoactuator is activated in the high frequency domain. A neuro-control algorithm is utilized to determine control electric field for the ER fluid, and H∞ control technique is adopted for the piezoactuator Comparative works between the proposed and single-actuating(ER fluid only or piezoactuator only) engine mounts are undertaken by evaluating force transmissibility over a wide operating frequency range.

Cue-based assertion classification for Swedish clinical text – developing a lexicon for pyConTextSwe

PubMed Central

Velupillai, Sumithra; Skeppstedt, Maria; Kvist, Maria; Mowery, Danielle; Chapman, Brian E.; Dalianis, Hercules; Chapman, Wendy W.

2014-01-01

Objective The ability of a cue-based system to accurately assert whether a disorder is affirmed, negated, or uncertain is dependent, in part, on its cue lexicon. In this paper, we continue our study of porting an assertion system (pyConTextNLP) from English to Swedish (pyConTextSwe) by creating an optimized assertion lexicon for clinical Swedish. Methods and material We integrated cues from four external lexicons, along with generated inflections and combinations. We used subsets of a clinical corpus in Swedish. We applied four assertion classes (definite existence, probable existence, probable negated existence and definite negated existence) and two binary classes (existence yes/no and uncertainty yes/no) to pyConTextSwe. We compared pyConTextSwe’s performance with and without the added cues on a development set, and improved the lexicon further after an error analysis. On a separate evaluation set, we calculated the system’s final performance. Results Following integration steps, we added 454 cues to pyConTextSwe. The optimized lexicon developed after an error analysis resulted in statistically significant improvements on the development set (83% F-score, overall). The system’s final F-scores on an evaluation set were 81% (overall). For the individual assertion classes, F-score results were 88% (definite existence), 81% (probable existence), 55% (probable negated existence), and 63% (definite negated existence). For the binary classifications existence yes/no and uncertainty yes/no, final system performance was 97%/87% and 78%/86% F-score, respectively. Conclusions We have successfully ported pyConTextNLP to Swedish (pyConTextSwe). We have created an extensive and useful assertion lexicon for Swedish clinical text, which could form a valuable resource for similar studies, and which is publicly available. PMID:24556644

Computational models of the Posner simple and choice reaction time tasks

PubMed Central

Feher da Silva, Carolina; Baldo, Marcus V. C.

2015-01-01

The landmark experiments by Posner in the late 1970s have shown that reaction time (RT) is faster when the stimulus appears in an expected location, as indicated by a cue; since then, the so-called Posner task has been considered a “gold standard” test of spatial attention. It is thus fundamental to understand the neural mechanisms involved in performing it. To this end, we have developed a Bayesian detection system and small integrate-and-fire neural networks, which modeled sensory and motor circuits, respectively, and optimized them to perform the Posner task under different cue type proportions and noise levels. In doing so, main findings of experimental research on RT were replicated: the relative frequency effect, suboptimal RTs and significant error rates due to noise and invalid cues, slower RT for choice RT tasks than for simple RT tasks, fastest RTs for valid cues and slowest RTs for invalid cues. Analysis of the optimized systems revealed that the employed mechanisms were consistent with related findings in neurophysiology. Our models predict that (1) the results of a Posner task may be affected by the relative frequency of valid and neutral trials, (2) in simple RT tasks, input from multiple locations are added together to compose a stronger signal, and (3) the cue affects motor circuits more strongly in choice RT tasks than in simple RT tasks. In discussing the computational demands of the Posner task, attention has often been described as a filter that protects the nervous system, whose capacity is limited, from information overload. Our models, however, reveal that the main problems that must be overcome to perform the Posner task effectively are distinguishing signal from external noise and selecting the appropriate response in the presence of internal noise. PMID:26190997

Amygdala subsystems and control of feeding behavior by learned cues.

PubMed

Petrovich, Gorica D; Gallagher, Michela

2003-04-01

A combination of behavioral studies and a neural systems analysis approach has proven fruitful in defining the role of the amygdala complex and associated circuits in fear conditioning. The evidence presented in this chapter suggests that this approach is also informative in the study of other adaptive functions that involve the amygdala. In this chapter we present a novel model to study learning in an appetitive context. Furthermore, we demonstrate that long-recognized connections between the amygdala and the hypothalamus play a crucial role in allowing learning to modulate feeding behavior. In the first part we describe a behavioral model for motivational learning. In this model a cue that acquires motivational properties through pairings with food delivery when an animal is hungry can override satiety and promote eating in sated rats. Next, we present evidence that a specific amygdala subsystem (basolateral area) is responsible for allowing such learned cues to control eating (override satiety and promote eating in sated rats). We also show that basolateral amygdala mediates these actions via connectivity with the lateral hypothalamus. Lastly, we present evidence that the amygdalohypothalamic system is specific for the control of eating by learned motivational cues, as it does not mediate another function that depends on intact basolateral amygdala, namely, the ability of a conditioned cue to support new learning based on its acquired value. Knowledge about neural systems through which food-associated cues specifically control feeding behavior provides a defined model for the study of learning. In addition, this model may be informative for understanding mechanisms of maladaptive aspects of learned control of eating that contribute to eating disorders and more moderate forms of overeating.

Design Definition Study Report. Full Crew Interaction Simulator-Laboratory Model (FCIS-LM) (Device X17B7). Volume II. Requirements.

DTIC Science & Technology

1978-06-01

stimulate at-least three levels of crew function. At the most complex level, visual cues are used to discriminate the presence or activities of...limited to motion on- set cues washed out at subliminal levels.. Because of the cues they provide the driver, gunner, and commander, and the dis...motion, i.e.,which physiological receptors are affected, how they function,and how they may be stimulated by a simulator motion system. I Motion is

14 CFR 25.1163 - Powerplant accessories.

Code of Federal Regulations, 2012 CFR

2012-01-01

... the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or sparking... to prevent rotation without interfering with the continued operation of the engine. [Doc. No. 5066... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine...

14 CFR 25.1163 - Powerplant accessories.

Code of Federal Regulations, 2011 CFR

2011-01-01

... the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or sparking... to prevent rotation without interfering with the continued operation of the engine. [Doc. No. 5066... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine...

14 CFR 25.1163 - Powerplant accessories.

Code of Federal Regulations, 2013 CFR

2013-01-01

... the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or sparking... to prevent rotation without interfering with the continued operation of the engine. [Doc. No. 5066... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine...

14 CFR 25.1163 - Powerplant accessories.

Code of Federal Regulations, 2014 CFR

2014-01-01

... the engine oil system and the accessory system. (b) Electrical equipment subject to arcing or sparking... to prevent rotation without interfering with the continued operation of the engine. [Doc. No. 5066... Powerplant accessories. (a) Each engine mounted accessory must— (1) Be approved for mounting on the engine...

Tracking a head-mounted display in a room-sized environment with head-mounted cameras

NASA Astrophysics Data System (ADS)

Wang, Jih-Fang; Azuma, Ronald T.; Bishop, Gary; Chi, Vernon; Eyles, John; Fuchs, Henry

1990-10-01

This paper presents our efforts to accurately track a Head-Mounted Display (HMD) in a large environment. We review our current benchtop prototype (introduced in {WCF9O]), then describe our plans for building the full-scale system. Both systems use an inside-oui optical tracking scheme, where lateraleffect photodiodes mounted on the user's helmet view flashing infrared beacons placed in the environment. Church's method uses the measured 2D image positions and the known 3D beacon locations to recover the 3D position and orientation of the helmet in real-time. We discuss the implementation and performance of the benchtop prototype. The full-scale system design includes ceiling panels that hold the infrared beacons and a new sensor arrangement of two photodiodes with holographic lenses. In the full-scale system, the user can walk almost anywhere under the grid of ceiling panels, making the working volume nearly as large as the room.

Detection and location of fouling on photovoltaic panels using a drone-mounted infrared thermography system

NASA Astrophysics Data System (ADS)

Zhang, Peng; Zhang, Lifu; Wu, Taixia; Zhang, Hongming; Sun, Xuejian

2017-01-01

Due to weathering and external forces, solar panels are subject to fouling and defects after a certain amount of time in service. These fouling and defects have direct adverse consequences such as low-power efficiency. Because solar power plants usually have large-scale photovoltaic (PV) panels, fast detection and location of fouling and defects across large PV areas are imperative. A drone-mounted infrared thermography system was designed and developed, and its ability to detect rapid fouling on large-scale PV panel systems was investigated. The infrared images were preprocessed using the K neighbor mean filter, and the single PV module on each image was recognized and extracted. Combining the local and global detection method, suspicious sites were located precisely. The results showed the flexible drone-mounted infrared thermography system to have a strong ability to detect the presence and determine the position of PV fouling. Drone-mounted infrared thermography also has good technical feasibility and practical value in the detection of PV fouling detection.

Cryogenic-Compatible Winchester Connector Mount and Retaining System for Composite Tubes

NASA Technical Reports Server (NTRS)

Pontius, James; McGuffey, Douglas

2011-01-01

A connector retainer and mounting system has been designed to replace screw-mounting of Winchester connectors. Countersunk screws are normally used to secure connectors to structures, and to keep them from coming apart. These screws are normally put into threaded or through-holes in metallic structures. This unique retainer is designed such that integral posts keep the connector halves retained, and a groove permits a cable tie to be fastened around the retainer and composite tube, thus securing the connector to the structure. The system is compatible for use on cryogenic (and conventional) bonded composite tube assemblies. Screws and tapped/through-holes needed to retain and mount Winchester connectors cannot be used on blind-access composite tubes. This system allows for rapid installation, removal, low-molecular-outgassing materials, and particulate-free installation and removal. Installation and/or changes late in the integration, and test flow with limited access in a cleanroom environment are possible. No sanding or bonding is needed.

An in flight investigation of pitch rate flight control systems and application of frequency domain and time domain predictive criteria

NASA Technical Reports Server (NTRS)

Berthe, C. J.; Chalk, C. R.; Sarrafian, S.

1984-01-01

The degree of attitude control provided by current integral-proportional pitch rate command-type control systems, while a prerequisite for flared landing, is insufficient for 'Level 1' performance. The pilot requires 'surrogate' feedback cues to precisely control flight path in the landing flare. Monotonic stick forces and pilot station vertical acceleration are important cues which can be provided by means of angle-of-attack and pitch rate feedback in order to achieve conventional short period and phugoid characteristics. Integral-proportional pitch rate flight control systems can be upgraded to Level 1 flared landing performance by means of lead/lag and washout prefilters in the command path. Strong pilot station vertical acceleration cues can provide Level 1 flared landing performance even in the absence of monotonic stick forces.

MPI CyberMotion Simulator: implementation of a novel motion simulator to investigate multisensory path integration in three dimensions.

PubMed

Barnett-Cowan, Michael; Meilinger, Tobias; Vidal, Manuel; Teufel, Harald; Bülthoff, Heinrich H

2012-05-10

Path integration is a process in which self-motion is integrated over time to obtain an estimate of one's current position relative to a starting point (1). Humans can do path integration based exclusively on visual (2-3), auditory (4), or inertial cues (5). However, with multiple cues present, inertial cues - particularly kinaesthetic - seem to dominate (6-7). In the absence of vision, humans tend to overestimate short distances (<5 m) and turning angles (<30°), but underestimate longer ones (5). Movement through physical space therefore does not seem to be accurately represented by the brain. Extensive work has been done on evaluating path integration in the horizontal plane, but little is known about vertical movement (see (3) for virtual movement from vision alone). One reason for this is that traditional motion simulators have a small range of motion restricted mainly to the horizontal plane. Here we take advantage of a motion simulator (8-9) with a large range of motion to assess whether path integration is similar between horizontal and vertical planes. The relative contributions of inertial and visual cues for path navigation were also assessed. 16 observers sat upright in a seat mounted to the flange of a modified KUKA anthropomorphic robot arm. Sensory information was manipulated by providing visual (optic flow, limited lifetime star field), vestibular-kinaesthetic (passive self motion with eyes closed), or visual and vestibular-kinaesthetic motion cues. Movement trajectories in the horizontal, sagittal and frontal planes consisted of two segment lengths (1st: 0.4 m, 2nd: 1 m; ±0.24 m/s(2) peak acceleration). The angle of the two segments was either 45° or 90°. Observers pointed back to their origin by moving an arrow that was superimposed on an avatar presented on the screen. Observers were more likely to underestimate angle size for movement in the horizontal plane compared to the vertical planes. In the frontal plane observers were more likely to overestimate angle size while there was no such bias in the sagittal plane. Finally, observers responded slower when answering based on vestibular-kinaesthetic information alone. Human path integration based on vestibular-kinaesthetic information alone thus takes longer than when visual information is present. That pointing is consistent with underestimating and overestimating the angle one has moved through in the horizontal and vertical planes respectively, suggests that the neural representation of self-motion through space is non-symmetrical which may relate to the fact that humans experience movement mostly within the horizontal plane.

Automated inspection of solder joints for surface mount technology

NASA Technical Reports Server (NTRS)

Savage, Robert M.; Park, Hyun Soo; Fan, Mark S.

1993-01-01

Researchers at NASA/GSFC evaluated various automated inspection systems (AIS) technologies using test boards with known defects in surface mount solder joints. These boards were complex and included almost every type of surface mount device typical of critical assemblies used for space flight applications: X-ray radiography; X-ray laminography; Ultrasonic Imaging; Optical Imaging; Laser Imaging; and Infrared Inspection. Vendors, representative of the different technologies, inspected the test boards with their particular machine. The results of the evaluation showed limitations of AIS. Furthermore, none of the AIS technologies evaluated proved to meet all of the inspection criteria for use in high-reliability applications. It was found that certain inspection systems could supplement but not replace manual inspection for low-volume, high-reliability, surface mount solder joints.

Design of an automated cart and mount for a hyperspectral imaging system to be used in produce fields

USDA-ARS?s Scientific Manuscript database

The goal of this project was to construct a cart and a mounting system that would allow a hyperspectral laser-induced fluorescence imaging system (HLIFIS) to be used to detect fecal material in produce fields. Fecal contaminated produce is a recognized food safety risk. Previous research demonstrate...

Propulsion and stabilization system for magnetically levitated vehicles

DOEpatents

Coffey, Howard T.

1993-06-29

A propulsion and stabilization system for an inductive repulsion type magnetically levitated vehicle which is propelled and stabilized by a system which includes propulsion windings mounted above and parallel to vehicle-borne suspension magnets. A linear synchronous motor is part of the vehicle guideway and is mounted above and parallel to superconducting magnets attached to the magnetically levitated vehicle.

Vestibular-visual interactions in flight simulators

NASA Technical Reports Server (NTRS)

Clark, B.

1977-01-01

The following research work is reported: (1) vestibular-visual interactions; (2) flight management and crew system interactions; (3) peripheral cue utilization in simulation technology; (4) control of signs and symptoms of motion sickness; (5) auditory cue utilization in flight simulators, and (6) vestibular function: Animal experiments.

Piloted Simulation to Evaluate the Utility of a Real Time Envelope Protection System for Mitigating In-Flight Icing Hazards

NASA Technical Reports Server (NTRS)

Ranaudo, Richard J.; Martos, Borja; Norton, Bill W.; Gingras, David R.; Barnhart, Billy P.; Ratvasky, Thomas P.; Morelli, Eugene

2011-01-01

The utility of the Icing Contamination Envelope Protection (ICEPro) system for mitigating a potentially hazardous icing condition was evaluated by 29 pilots using the NASA Ice Contamination Effects Flight Training Device (ICEFTD). ICEPro provides real time envelope protection cues and alerting messages on pilot displays. The pilots participating in this test were divided into two groups; a control group using baseline displays without ICEPro, and an experimental group using ICEPro driven display cueing. Each group flew identical precision approach and missed approach procedures with a simulated failure case icing condition. Pilot performance, workload, and survey questionnaires were collected for both groups of pilots. Results showed that real time assessment cues were effective in reducing the number of potentially hazardous upset events and in lessening exposure to loss of control following an incipient upset condition. Pilot workload with the added ICEPro displays was not measurably affected, but pilot opinion surveys showed that real time cueing greatly improved their situation awareness of a hazardous aircraft state.

Weatherwise: evaluation of a cue-based training approach for the recognition of deteriorating weather conditions during flight.

PubMed

Wiggins, Mark; O'Hare, David

2003-01-01

Inappropriate and ineffective weather-related decision making continues to account for a significant proportion of general aviation fatalities in the United States and elsewhere. This study details the evaluation of a computer-based training system that was developed to provide visual pilots with the skills necessary to recognize and respond to the cues associated with deteriorating weather conditions during flight. A total of 66 pilots were assigned to one of two groups, and the evaluation process was undertaken at both a self-report and performance level. At the self-report level, the results suggested that pilots were more likely to use the cues following exposure to the training program. From a performance perspective, there is evidence to suggest that cue-based training can improve the timeliness of weather-related decision making during visual flight rules flight. Actual or potential applications of this research include the development of computer-based training systems for fault diagnosis in complex industrial environments.

Synthetic vision display evaluation studies

NASA Technical Reports Server (NTRS)

Regal, David M.; Whittington, David H.

1994-01-01

The goal of this research was to help us understand the display requirements for a synthetic vision system for the High Speed Civil Transport (HSCT). Four experiments were conducted to examine the effects of different levels of perceptual cue complexity in displays used by pilots in a flare and landing task. Increased levels of texture mapping of terrain and runway produced mixed results, including harder but shorter landings and a lower flare initiation altitude. Under higher workload conditions, increased texture resulted in an improvement in performance. An increase in familiar size cues did not result in improved performance. Only a small difference was found between displays using two patterns of high resolution texture mapping. The effects of increased perceptual cue complexity on performance was not as strong as would be predicted from the pilot's subjective reports or from related literature. A description of the role of a synthetic vision system in the High Speed Civil Transport is provide along with a literature review covering applied research related to perceptual cue usage in aircraft displays.

Decentralized Multisensory Information Integration in Neural Systems.

PubMed

Zhang, Wen-Hao; Chen, Aihua; Rasch, Malte J; Wu, Si

2016-01-13

How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that the decentralized system can integrate information optimally, with the reciprocal connections between processers determining the extent of cue integration. Our model reproduces known multisensory integration behaviors observed in experiments and sheds new light on our understanding of how information is integrated in the brain. Copyright © 2016 Zhang et al.

Decentralized Multisensory Information Integration in Neural Systems

PubMed Central

Zhang, Wen-hao; Chen, Aihua

2016-01-01

How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. SIGNIFICANCE STATEMENT To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that the decentralized system can integrate information optimally, with the reciprocal connections between processers determining the extent of cue integration. Our model reproduces known multisensory integration behaviors observed in experiments and sheds new light on our understanding of how information is integrated in the brain. PMID:26758843

Multisensory control of a straight locomotor trajectory.

PubMed

Hanna, Maxim; Fung, Joyce; Lamontagne, Anouk

2017-01-01

Locomotor steering is contingent upon orienting oneself spatially in the environment. When the head is turned while walking, the optic flow projected onto the retina is a complex pattern comprising of a translational and a rotational component. We have created a unique paradigm to simulate different optic flows in a virtual environment. We hypothesized that non-visual (vestibular and somatosensory) cues are required for proper control of a straight trajectory while walking. This research study included 9 healthy young subjects walking in a large physical space (40×25m2) while the virtual environment is viewed in a helmet-mounted display. They were instructed to walk straight in the physical world while being exposed to three conditions: (1) self-initiated active head turns (AHT: 40° right, left, or none); (2) visually simulated head turns (SHT); and (3) visually simulated head turns with no target element (SHT_NT). Conditions 1 and 2 involved an eye-level target which subjects were instructed to fixate, whereas condition 3 was similar to condition 2 but with no target. Identical retinal flow patterns were present in the AHT and SHT conditions whereas non-visual cues differed in that a head rotation was sensed only in AHT but not in SHT. Body motions were captured by a 12-camera Vicon system. Horizontal orientations of the head and body segments, as well as the trajectory of the body's centre of mass were analyzed. SHT and SNT_NT yielded similar results. Heading and body segment orientations changed in the direction opposite to the head turns in SHT conditions. Heading remained unchanged across head turn directions in AHT. Results suggest that non-visual information is used in the control of heading while being exposed to changing rotational optic flows. The small magnitude of the changes in SHT conditions suggests that the CNS can re-weight relevant sources of information to minimize heading errors in the presence of sensory conflicts.

Creating a competitive PSO: a case study.

PubMed

Calvaruso, J T

1999-06-01

Mount Carmel Health System, an integrated delivery system in Columbus, Ohio, became a Medicare+Choice contractor in response to unsatisfactory payment proposals from the Medicare contractors it serviced and to compete with the increasing number of managed care providers in its market. To meet HCFA's operational requirements, Mount Carmel upgraded and expanded its administrative and health information systems and solicited the support of its network physicians. It also developed a marketing strategy to promote its health plan. In the two years after instituting its provider-sponsored organization, Mount Carmel surpassed its original enrollment projections, decreased its patient management and utilization costs, and increased payments to its network members.

Capture by colour: evidence for dimension-specific singleton capture.

PubMed

Harris, Anthony M; Becker, Stefanie I; Remington, Roger W

2015-10-01

Previous work on attentional capture has shown the attentional system to be quite flexible in the stimulus properties it can be set to respond to. Several different attentional "modes" have been identified. Feature search mode allows attention to be set for specific features of a target (e.g., red). Singleton detection mode sets attention to respond to any discrepant item ("singleton") in the display. Relational search sets attention for the relative properties of the target in relation to the distractors (e.g., redder, larger). Recently, a new attentional mode was proposed that sets attention to respond to any singleton within a particular feature dimension (e.g., colour; Folk & Anderson, 2010). We tested this proposal against the predictions of previously established attentional modes. In a spatial cueing paradigm, participants searched for a colour target that was randomly either red or green. The nature of the attentional control setting was probed by presenting an irrelevant singleton cue prior to the target display and assessing whether it attracted attention. In all experiments, the cues were red, green, blue, or a white stimulus rapidly rotated (motion cue). The results of three experiments support the existence of a "colour singleton set," finding that all colour cues captured attention strongly, while motion cues captured attention only weakly or not at all. Notably, we also found that capture by motion cues in search for colour targets was moderated by their frequency; rare motion cues captured attention (weakly), while frequent motion cues did not.

Toward understanding social cues and signals in human–robot interaction: effects of robot gaze and proxemic behavior

PubMed Central

Fiore, Stephen M.; Wiltshire, Travis J.; Lobato, Emilio J. C.; Jentsch, Florian G.; Huang, Wesley H.; Axelrod, Benjamin

2013-01-01

As robots are increasingly deployed in settings requiring social interaction, research is needed to examine the social signals perceived by humans when robots display certain social cues. In this paper, we report a study designed to examine how humans interpret social cues exhibited by robots. We first provide a brief overview of perspectives from social cognition in humans and how these processes are applicable to human–robot interaction (HRI). We then discuss the need to examine the relationship between social cues and signals as a function of the degree to which a robot is perceived as a socially present agent. We describe an experiment in which social cues were manipulated on an iRobot AvaTM mobile robotics platform in a hallway navigation scenario. Cues associated with the robot’s proxemic behavior were found to significantly affect participant perceptions of the robot’s social presence and emotional state while cues associated with the robot’s gaze behavior were not found to be significant. Further, regardless of the proxemic behavior, participants attributed more social presence and emotional states to the robot over repeated interactions than when they first interacted with it. Generally, these results indicate the importance for HRI research to consider how social cues expressed by a robot can differentially affect perceptions of the robot’s mental states and intentions. The discussion focuses on implications for the design of robotic systems and future directions for research on the relationship between social cues and signals. PMID:24348434

Toward understanding social cues and signals in human-robot interaction: effects of robot gaze and proxemic behavior.

PubMed

Fiore, Stephen M; Wiltshire, Travis J; Lobato, Emilio J C; Jentsch, Florian G; Huang, Wesley H; Axelrod, Benjamin

2013-01-01

As robots are increasingly deployed in settings requiring social interaction, research is needed to examine the social signals perceived by humans when robots display certain social cues. In this paper, we report a study designed to examine how humans interpret social cues exhibited by robots. We first provide a brief overview of perspectives from social cognition in humans and how these processes are applicable to human-robot interaction (HRI). We then discuss the need to examine the relationship between social cues and signals as a function of the degree to which a robot is perceived as a socially present agent. We describe an experiment in which social cues were manipulated on an iRobot Ava(TM) mobile robotics platform in a hallway navigation scenario. Cues associated with the robot's proxemic behavior were found to significantly affect participant perceptions of the robot's social presence and emotional state while cues associated with the robot's gaze behavior were not found to be significant. Further, regardless of the proxemic behavior, participants attributed more social presence and emotional states to the robot over repeated interactions than when they first interacted with it. Generally, these results indicate the importance for HRI research to consider how social cues expressed by a robot can differentially affect perceptions of the robot's mental states and intentions. The discussion focuses on implications for the design of robotic systems and future directions for research on the relationship between social cues and signals.

Integration of reward signalling and appetite regulating peptide systems in the control of food-cue responses.

PubMed

Reichelt, A C; Westbrook, R F; Morris, M J

2015-11-01

Understanding the neurobiological substrates that encode learning about food-associated cues and how those signals are modulated is of great clinical importance especially in light of the worldwide obesity problem. Inappropriate or maladaptive responses to food-associated cues can promote over-consumption, leading to excessive energy intake and weight gain. Chronic exposure to foods rich in fat and sugar alters the reinforcing value of foods and weakens inhibitory neural control, triggering learned, but maladaptive, associations between environmental cues and food rewards. Thus, responses to food-associated cues can promote cravings and food-seeking by activating mesocorticolimbic dopamine neurocircuitry, and exert physiological effects including salivation. These responses may be analogous to the cravings experienced by abstaining drug addicts that can trigger relapse into drug self-administration. Preventing cue-triggered eating may therefore reduce the over-consumption seen in obesity and binge-eating disorder. In this review we discuss recent research examining how cues associated with palatable foods can promote reward-based feeding behaviours and the potential involvement of appetite-regulating peptides including leptin, ghrelin, orexin and melanin concentrating hormone. These peptide signals interface with mesolimbic dopaminergic regions including the ventral tegmental area to modulate reactivity to cues associated with palatable foods. Thus, a novel target for anti-obesity therapeutics is to reduce non-homeostatic, reward driven eating behaviour, which can be triggered by environmental cues associated with highly palatable, fat and sugar rich foods. © 2015 The British Pharmacological Society.

Reducing Visual Discomfort with HMDs Using Dynamic Depth of Field.

PubMed

Carnegie, Kieran; Rhee, Taehyun

2015-01-01

Although head-mounted displays (HMDs) are ideal devices for personal viewing of immersive stereoscopic content, exposure to VR applications on them results in significant discomfort for the majority of people, with symptoms including eye fatigue, headaches, nausea, and sweating. A conflict between accommodation and vergence depth cues on stereoscopic displays is a significant cause of visual discomfort. This article describes the results of an evaluation used to judge the effectiveness of dynamic depth-of-field (DoF) blur in an effort to reduce discomfort caused by exposure to stereoscopic content on HMDs. Using a commercial game engine implementation, study participants report a reduction of visual discomfort on a simulator sickness questionnaire when DoF blurring is enabled. The study participants reported a decrease in symptom severity caused by HMD exposure, indicating that dynamic DoF can effectively reduce visual discomfort.

Marine Chemical Ecology: Chemical Signals and Cues Structure Marine Populations, Communities, and Ecosystems

PubMed Central

Hay, Mark E.

2012-01-01

Chemical cues constitute much of the language of life in the sea. Our understanding of biotic interactions and their effects on marine ecosystems will advance more rapidly if this language is studied and understood. Here, I review how chemical cues regulate critical aspects of the behavior of marine organisms from bacteria to phytoplankton to benthic invertebrates and water column fishes. These chemically mediated interactions strongly affect population structure, community organization, and ecosystem function. Chemical cues determine foraging strategies, feeding choices, commensal associations, selection of mates and habitats, competitive interactions, and transfer of energy and nutrients within and among ecosystems. In numerous cases, the indirect effects of chemical signals on behavior have as much or more effect on community structure and function as the direct effects of consumers and pathogens. Chemical cues are critical for understanding marine systems, but their omnipresence and impact are inadequately recognized. PMID:21141035

NEURAL SUBSTRATES OF CUE-REACTIVITY: ASSOCIATION WITH TREATMENT OUTCOMES AND RELAPSE

PubMed Central

Courtney, Kelly E.; Schacht, Joseph P.; Hutchison, Kent; Roche, Daniel J.O.; Ray, Lara A.

2016-01-01

Given the strong evidence for neurological alterations at the basis of drug dependence, functional magnetic resonance imaging (fMRI) represents an important tool in the clinical neuroscience of addiction. fMRI cue-reactivity paradigms represent an ideal platform to probe the involvement of neurobiological pathways subserving the reward/motivation system in addiction and potentially offer a translational mechanism by which interventions and behavioral predictions can be tested. Thus, this review summarizes the research that has applied fMRI cue-reactivity paradigms to the study of adult substance use disorder treatment responses. Studies utilizing fMRI cue-reactivity paradigms for the prediction of relapse, and as a means to investigate psychosocial and pharmacological treatment effects on cue-elicited brain activation are presented within four primary categories of substances: alcohol, nicotine, cocaine, and opioids. Lastly, suggestions for how to leverage fMRI technology to advance addiction science and treatment development are provided. PMID:26435524

A rotor-mounted digital instrumentation system for helicopter blade flight research measurements

NASA Technical Reports Server (NTRS)

Knight, V. H., Jr.; Haywood, W. S., Jr.; Williams, M. L.

1978-01-01

A rotor mounted flight instrumentation system developed for helicopter rotor blade research is described. The system utilizes high speed digital techniques to acquire research data from miniature pressure transducers on advanced rotor airfoils which are flight tested on an AH-1G helicopter. The system employs microelectronic pulse code modulation (PCM) multiplexer digitizer stations located remotely on the blade and in a hub mounted metal canister. As many as 25 sensors can be remotely digitized by a 2.5 mm thick electronics package mounted on the blade near the tip to reduce blade wiring. The electronics contained in the canister digitizes up to 16 sensors, formats these data with serial PCM data from the remote stations, and transmits the data from the canister which is above the plane of the rotor. Data are transmitted over an RF link to the ground for real time monitoring and to the helicopter fuselage for tape recording. The complete system is powered by batteries located in the canister and requires no slip rings on the rotor shaft.

Head Mounted Displays for Virtual Reality

DTIC Science & Technology

1993-02-01

Produce an Image of Infinity 9 3 The Naval Ocean Systems Center HMD with Front-Mounted CRTs 10 4 The VR Group HMD with Side-Mounted CRTs. The Image is...Convergence Angles 34 vii SECTION 1 INTRODUCTION One of the goals in the development of Virtual Reality ( VR ) is to achieve "total immersion" where one...become transported out of the real world and into the virtual world. The developers of VR have utilized the head mounted display (HMD) as a means of

Learning to Use Illumination Gradients as an Unambiguous Cue to Three Dimensional Shape

PubMed Central

Harding, Glen; Harris, Julie M.; Bloj, Marina

2012-01-01

The luminance and colour gradients across an image are the result of complex interactions between object shape, material and illumination. Using such variations to infer object shape or surface colour is therefore a difficult problem for the visual system. We know that changes to the shape of an object can affect its perceived colour, and that shading gradients confer a sense of shape. Here we investigate if the visual system is able to effectively utilise these gradients as a cue to shape perception, even when additional cues are not available. We tested shape perception of a folded card object that contained illumination gradients in the form of shading and more subtle effects such as inter-reflections. Our results suggest that observers are able to use the gradients to make consistent shape judgements. In order to do this, observers must be given the opportunity to learn suitable assumptions about the lighting and scene. Using a variety of different training conditions, we demonstrate that learning can occur quickly and requires only coarse information. We also establish that learning does not deliver a trivial mapping between gradient and shape; rather learning leads to the acquisition of assumptions about lighting and scene parameters that subsequently allow for gradients to be used as a shape cue. The perceived shape is shown to be consistent for convex and concave versions of the object that exhibit very different shading, and also similar to that delivered by outline, a largely unrelated cue to shape. Overall our results indicate that, although gradients are less reliable than some other cues, the relationship between gradients and shape can be quickly assessed and the gradients therefore used effectively as a visual shape cue. PMID:22558279

Common influences of non-competitive NMDA receptor antagonists on the consolidation and reconsolidation of cocaine-cue memory.

PubMed

Alaghband, Yasaman; Marshall, John F

2013-04-01

Environmental stimuli or contexts previously associated with rewarding drugs contribute importantly to relapse among addicts, and research has focused on neurobiological processes maintaining those memories. Much research shows contributions of cell surface receptors and intracellular signaling pathways in maintaining associations between rewarding drugs (e.g., cocaine) and concurrent cues/contexts; these memories can be degraded at the time of their retrieval through reconsolidation interference. Much less studied is the consolidation of drug-cue memories during their acquisition. The present experiments use the cocaine-conditioned place preference (CPP) paradigm in rats to directly compare, in a consistent setting, the effects of N-methyl-D-aspartate (NMDA) glutamate receptor antagonists MK-801 and memantine on the consolidation and reconsolidation of cocaine-cue memories. For the consolidation studies, animals were systemically administered MK-801 or memantine immediately following training sessions. To investigate the effects of these NMDA receptor antagonists on the retention of previously established cocaine-cue memories, animals were systemically administered MK-801 or memantine immediately after memory retrieval. Animals given either NMDA receptor antagonist immediately following training sessions did not establish a preference for the cocaine-paired compartment. Post-retrieval administration of either NMDA receptor antagonist attenuated the animals' preference for the cocaine-paired compartment. Furthermore, animals given NMDA receptor antagonists post-retrieval showed a blunted response to cocaine-primed reinstatement. Using two distinct NMDA receptor antagonists in a common setting, these findings demonstrate that NMDA receptor-dependent processes contribute both to the consolidation and reconsolidation of cocaine-cue memories, and they point to the potential utility of treatments that interfere with drug-cue memory reconsolidation.

Elemental or contextual? It depends: individual difference in the hippocampal dependence of associative learning for a simple sensory stimulus

PubMed Central

Lee, Kyung J.; Park, Seong-Beom; Lee, Inah

2014-01-01

Learning theories categorize learning systems into elemental and contextual systems, the former being processed by non-hippocampal regions and the latter being processed in the hippocampus. A set of complex stimuli such as a visual background is often considered a contextual stimulus and simple sensory stimuli such as pure tone and light are considered elemental stimuli. However, this elemental-contextual categorization scheme has only been tested in limited behavioral paradigms and it is largely unknown whether it can be generalized across different learning situations. By requiring rats to respond differently to a common object in association with various types of sensory cues including contextual and elemental stimuli, we tested whether different types of elemental and contextual sensory stimuli depended on the hippocampus to different degrees. In most rats, a surrounding visual background and a tactile stimulus served as contextual (hippocampal dependent) and elemental (non-hippocampal dependent) stimuli, respectively. However, simple tone and light stimuli frequently used as elemental cues in traditional experiments required the hippocampus to varying degrees among rats. Specifically, one group of rats showed a normal contextual bias when both contextual and elemental cues were present. These rats effectively switched to using elemental cues when the hippocampus was inactivated. The other group showed a strong contextual bias (and hippocampal dependence) because these rats were not able to use elemental cues when the hippocampus was unavailable. It is possible that the latter group of rats might have interpreted the elemental cues (light and tone) as background stimuli and depended more on the hippocampus in associating the cues with choice responses. Although exact mechanisms underlying these individual variances are unclear, our findings recommend a caution for adopting a simple sensory stimulus as a non-hippocampal sensory cue only based on the literature. PMID:24982624

Scrubbing masks magmatic degassing during repose at Cascade-Range and Aleutian-Arc volcanoes

USGS Publications Warehouse

Symonds, Robert B.; Janik, C.J.; Evans, William C.; Ritchie, B.E.; Counce, Dale; Poreda, R.J.; Iven, Mark

2003-01-01

Between 1992 and 1998, we sampled gas discharges from ≤173°C fumaroles and springs at 12 quiescent but potentially restless volcanoes in the Cascade Range and Aleutian Arc (CRAA) including Mount Shasta, Mount Hood, Mount St. Helens, Mount Rainier, Mount Baker, Augustine Volcano, Mount Griggs, Trident, Mount Mageik, Aniakchak Crater, Akutan, and Makushin. For each site, we collected and analyzed samples to characterize the chemical (H2O, CO2, H2S, N2, CH4, H2, HCl, HF, NH3, Ar, O2, He) and isotopic (δ13C of CO2, 3He/4He, 40Ar/36Ar, δ34S, δ13C of CH4, δ15N, and δD and δ18O of water) compositions of the gas discharges, and to create baseline data for comparison during future unrest. The chemical and isotopic data show that these gases contain a magmatic component that is heavily modified from scrubbing by deep hydrothermal (150° - 350°C) water (primary scrubbing) and shallow meteoric water (secondary scrubbing). The impact of scrubbing is most pronounced in gas discharges from bubbling springs; gases from boiling-point fumaroles and superheated vents show progressively less impact from scrubbing. The most effective strategies for detecting gas precursors to future CRAA eruptions are to measure periodically the emission rates of CO2 and SO2, which have low and high respective solubilities in water, and to monitor continuously CO2 concentrations in soils around volcanic vents. Timely resampling of fumaroles can augment the geochemical surveillance program by watching for chemical changes associated with drying of fumarolic pathways (all CRAA sites), increases in gas geothermometry temperatures (Mount Mageik, Trident, Mount Baker, Mount Shasta), changes in δ13C of CO2 affiliated with magma movement (all CRAA site), and increases in 3He/4He coupled with intrusion of new magma (Mount Rainier, Augustine Volcano, Makushin, Mount Shasta). Repose magmatic degassing may discharge substantial amounts of S and Cl into the edifices of Mount Baker and several other CRAA volcanoes that is trapped by primary and secondary scrubbing. The consequent acidic fluids produce ongoing alteration in the 0.2- to 3-km-deep hydrothermal systems and in fields of boiling-point fumaroles near the surface. Such alteration may influence edifice stability and contribute to the formation of more-hazardous cohesive debris flows. In particular, we recommend further investigation of the volume, extent, and hazards of hydrothermal alteration at Mount Baker. Other potential hazards associated with the CRAA volcano hydrothermal systems include hydrothermal eruptions and, for deeper systems intruded by magma, deep-seated edifice collapse.

Mount Sinai Hospital's approach to Ontario's Health System Funding Reform.

PubMed

Chalk, Tyler; Lau, Davina; Morgan, Matthew; Dietrich, Sandra; Beduz, Mary Agnes; Bell, Chaim M

2014-01-01

In April 2012, the Ontario government introduced Health System Funding Reform (HSFR), a transformational shift in how hospitals are funded. Mount Sinai Hospital recognized that moving from global funding to a "patient-based" model would have substantial operational and clinical implications. Adjusting to the new funding environment was set as a top corporate priority, serving as the strategic basis for re-examining and redesigning operations to further improve both quality and efficiency. Two years into HSFR, this article outlines Mount Sinai Hospital's approach and highlights key lessons learned. Copyright © 2014 Longwoods Publishing.

Wind instrument mountings for above-the-cab lookout exposure

Treesearch

Owen P. Cramer; Ralph H. Moltzau

1968-01-01

The lookout tower offers a ready-made platform from which the speed of true unobstructed wind can be measured, then reduced to equivalent of 20-foot wind. Tower-mounted instruments must meet the requirements of a lightning conductor system, but should also be easily installed and removed for storage and maintenance. Lightweight aluminum mountings for catwalk or flat-...

47 CFR 15.253 - Operation within the bands 46.7-46.9 GHz and 76.0-77.0 GHz.

Code of Federal Regulations, 2014 CFR

2014-10-01

... restricted to vehicle-mounted field disturbance sensors used as vehicle radar systems. The transmission of...-mounted field disturbance sensor. Operation under the provisions of this section is not permitted on... structure. (2) For forward-looking vehicle mounted field disturbance sensors, if the vehicle is in motion...

47 CFR 15.253 - Operation within the bands 46.7-46.9 GHz and 76.0-77.0 GHz.

Code of Federal Regulations, 2013 CFR

2013-10-01

... restricted to vehicle-mounted field disturbance sensors used as vehicle radar systems. The transmission of...-mounted field disturbance sensor. Operation under the provisions of this section is not permitted on... structure. (2) For forward-looking vehicle mounted field disturbance sensors, if the vehicle is in motion...

47 CFR 15.253 - Operation within the bands 46.7-46.9 GHz and 76.0-77.0 GHz.

Code of Federal Regulations, 2012 CFR

2012-10-01

... restricted to vehicle-mounted field disturbance sensors used as vehicle radar systems. The transmission of...-mounted field disturbance sensor. Operation under the provisions of this section is not permitted on... structure. (2) For forward-looking vehicle mounted field disturbance sensors, if the vehicle is in motion...

A balance of activity in brain control and reward systems predicts self-regulatory outcomes

PubMed Central

Chen, Pin-Hao A.; Huckins, Jeremy F.; Hofmann, Wilhelm; Kelley, William M.; Heatherton, Todd F.

2017-01-01

Abstract Previous neuroimaging work has shown that increased reward-related activity following exposure to food cues is predictive of self-control failure. The balance model suggests that self-regulation failures result from an imbalance in reward and executive control mechanisms. However, an open question is whether the relative balance of activity in brain systems associated with executive control (vs reward) supports self-regulatory outcomes when people encounter tempting cues in daily life. Sixty-nine chronic dieters, a population known for frequent lapses in self-control, completed a food cue-reactivity task during an fMRI scanning session, followed by a weeklong sampling of daily eating behaviors via ecological momentary assessment. We related participants’ food cue activity in brain systems associated with executive control and reward to real-world eating patterns. Specifically, a balance score representing the amount of activity in brain regions associated with self-regulatory control, relative to automatic reward-related activity, predicted dieters’ control over their eating behavior during the following week. This balance measure may reflect individual self-control capacity and be useful for examining self-regulation success in other domains and populations. PMID:28158874

A balance of activity in brain control and reward systems predicts self-regulatory outcomes.

PubMed

Lopez, Richard B; Chen, Pin-Hao A; Huckins, Jeremy F; Hofmann, Wilhelm; Kelley, William M; Heatherton, Todd F

2017-05-01

Previous neuroimaging work has shown that increased reward-related activity following exposure to food cues is predictive of self-control failure. The balance model suggests that self-regulation failures result from an imbalance in reward and executive control mechanisms. However, an open question is whether the relative balance of activity in brain systems associated with executive control (vs reward) supports self-regulatory outcomes when people encounter tempting cues in daily life. Sixty-nine chronic dieters, a population known for frequent lapses in self-control, completed a food cue-reactivity task during an fMRI scanning session, followed by a weeklong sampling of daily eating behaviors via ecological momentary assessment. We related participants' food cue activity in brain systems associated with executive control and reward to real-world eating patterns. Specifically, a balance score representing the amount of activity in brain regions associated with self-regulatory control, relative to automatic reward-related activity, predicted dieters' control over their eating behavior during the following week. This balance measure may reflect individual self-control capacity and be useful for examining self-regulation success in other domains and populations. © The Author (2017). Published by Oxford University Press.

Judging sound rotation when listeners and sounds rotate: Sound source localization is a multisystem process.

PubMed

Yost, William A; Zhong, Xuan; Najam, Anbar

2015-11-01

In four experiments listeners were rotated or were stationary. Sounds came from a stationary loudspeaker or rotated from loudspeaker to loudspeaker around an azimuth array. When either sounds or listeners rotate the auditory cues used for sound source localization change, but in the everyday world listeners perceive sound rotation only when sounds rotate not when listeners rotate. In the everyday world sound source locations are referenced to positions in the environment (a world-centric reference system). The auditory cues for sound source location indicate locations relative to the head (a head-centric reference system), not locations relative to the world. This paper deals with a general hypothesis that the world-centric location of sound sources requires the auditory system to have information about auditory cues used for sound source location and cues about head position. The use of visual and vestibular information in determining rotating head position in sound rotation perception was investigated. The experiments show that sound rotation perception when sources and listeners rotate was based on acoustic, visual, and, perhaps, vestibular information. The findings are consistent with the general hypotheses and suggest that sound source localization is not based just on acoustics. It is a multisystem process.

A structural comparison of female-male and female-female mounting in Japanese macaques (Macaca fuscata).

PubMed

Ottenheimer Carrier, Lydia; Leca, Jean-Baptiste; Pellis, Sergio; Vasey, Paul L

2015-10-01

In certain populations, female Japanese macaques (Macaca fuscata) mount both males and females. Vasey (2007) proposed that female-female sexual mounting in Japanese macaques may be a neutral evolutionary by-product of a purported adaptation, namely, female-male mounting. In this study, we aim to further examine the proposed link between female-male and female-female mounting in Japanese macaques by comparing the structural characteristics that define both forms of mounting. We do so using Eshkol-Wachman Movement Notation (EWMN), a globographic reference system that can be used to describe the position of body segments. No significant differences were observed in the female mounters' positioning of eight different body segments (i.e., lower torso, mid-torso, upper torso, upper arm, lower arm, upper leg, lower leg, and foot) during female-male and female-female mounting. This finding lends support to the conclusion that female-female and female-male mounting are structurally, and thus, evolutionarily, related. Copyright © 2015 Elsevier B.V. All rights reserved.

In the blink of an eye: head mounted displays development within BAE Systems

NASA Astrophysics Data System (ADS)

Cameron, Alex

2015-05-01

There has been an explosion of interest in head worn displays in recent years, particularly for consumer applications with an attendant ramping up of investment into key enabling technologies to provide what is essence a mobile computer display. However, head mounted system have been around for over 40 years and today's consumer products are building on a legacy of knowledge and technology created by companies such as BAE Systems who have been designing and fielding helmet mounted displays (HMD) for a wide range of specialist applications. Although the dominant application area has been military aviation, solutions have been fielded for solider, ground vehicle, simulation, medical, racing car and even subsea navigation applications. What sets these HMDs apart is that they provide the user with accurate conformal information embedded in the users real world view where the information presented is intuitive and easy to use because it overlays the real world and enables them to stay head up, eyes out, - improving their effectiveness, reducing workload and improving safety. Such systems are an enabling technology in the provision of enhanced Situation Awareness (SA) and reducing user workload in high intensity situations. These capabilities are finding much wider application in new types of compact man mounted audio/visual products enabled by the emergence of new families of micro displays, novel optical concepts and ultra-compact low power processing solutions. This paper therefore provides a personal summary of BAE Systems 40 year's journey in developing and fielding Head Mounted systems, their applications.

Valenced cues and contexts have different effects on event-based prospective memory.

PubMed

Graf, Peter; Yu, Martin

2015-01-01

This study examined the separate influence and joint influences on event-based prospective memory task performance due to the valence of cues and the valence of contexts. We manipulated the valence of cues and contexts with pictures from the International Affective Picture System. The participants, undergraduate students, showed higher performance when neutral compared to valenced pictures were used for cueing prospective memory. In addition, neutral pictures were more effective as cues when they occurred in a valenced context than in the context of neutral pictures, but the effectiveness of valenced cues did not vary across contexts that differed in valence. The finding of an interaction between cue and context valence indicates that their respective influence on event-based prospective memory task performance cannot be understood in isolation from each other. Our findings are not consistent with by the prevailing view which holds that the scope of attention is broadened and narrowed, respectively, by positively and negatively valenced stimuli. Instead, our findings are more supportive of the recent proposal that the scope of attention is determined by the motivational intensity associated with valenced stimuli. Consistent with this proposal, we speculate that the motivational intensity associated with different retrieval cues determines the scope of attention, that contexts with different valence values determine participants' task engagement, and that prospective memory task performance is determined jointly by attention scope and task engagement.

Valenced Cues and Contexts Have Different Effects on Event-Based Prospective Memory

PubMed Central

Graf, Peter; Yu, Martin

2015-01-01

This study examined the separate influence and joint influences on event-based prospective memory task performance due to the valence of cues and the valence of contexts. We manipulated the valence of cues and contexts with pictures from the International Affective Picture System. The participants, undergraduate students, showed higher performance when neutral compared to valenced pictures were used for cueing prospective memory. In addition, neutral pictures were more effective as cues when they occurred in a valenced context than in the context of neutral pictures, but the effectiveness of valenced cues did not vary across contexts that differed in valence. The finding of an interaction between cue and context valence indicates that their respective influence on event-based prospective memory task performance cannot be understood in isolation from each other. Our findings are not consistent with by the prevailing view which holds that the scope of attention is broadened and narrowed, respectively, by positively and negatively valenced stimuli. Instead, our findings are more supportive of the recent proposal that the scope of attention is determined by the motivational intensity associated with valenced stimuli. Consistent with this proposal, we speculate that the motivational intensity associated with different retrieval cues determines the scope of attention, that contexts with different valence values determine participants’ task engagement, and that prospective memory task performance is determined jointly by attention scope and task engagement. PMID:25647484

Can cleanerfish overcome temptation? A selective role for dopamine influence on cooperative-based decision making.

PubMed

Soares, Marta C; Cardoso, Sónia C; Malato, João T; Messias, João P M

2017-02-01

Evidence suggests that animals are selected to make accurate choices and prioritize goals within the constraints of a given social environment to maximize fitness. These decisions are mostly based on complex processes in which value is linked to reward and cues may carry variable incentive salience. However, the level in which the incentive elicited by a cue is able to shift individual choices should differ between individuals and neurophysiological states. Here we used a notorious cooperative cleanerfish species Labroides dimidiatus to probe for differences in the incentive motivational valences given to food cues and then tested for the role of the dopaminergic system in the appraisal of such cues. We found that cleaners differed in Pavlovian conditioned approach behavioural responses to reward-associated stimuli: while the majority were fast to engage physically with the cue plate that indicated future reward delivery (sign trackers), only a few took significantly more time to respond (goal trackers). But amongst those that were considering the sole cue attractive, we discovered that the dopaminergic blockage decreased their initial propensity to approach and touch the cue plate. Our results show that dopamine disruption contributes to shifting the attribution of motivational incentive from the predictive cue towards the actual reward and provides key insight into the physiological framework of cooperative-based decision making. Copyright © 2016 Elsevier Inc. All rights reserved.

Commercial/industrial photovoltaic module and array requirement study. Low-cost solar array project engineering area

NASA Technical Reports Server (NTRS)

1981-01-01

Design requirements for photovoltaic modules and arrays used in commercial and industrial applications were identified. Building codes and referenced standards were reviewed for their applicability to commercial and industrial photovoltaic array installation. Four general installation types were identified - integral (replaces roofing), direct (mounted on top of roofing), stand-off (mounted away from roofing), and rack (for flat or low slope roofs, or ground mounted). Each of the generic mounting types can be used in vertical wall mounting systems. This implies eight mounting types exist in the commercial/industrial sector. Installation costs were developed for these mounting types as a function of panel/module size. Cost drivers were identified. Studies were performed to identify optimum module shapes and sizes and operating voltage cost drivers. The general conclusion is that there are no perceived major obstacles to the use of photovoltaic modules in commercial/industrial arrays.

Assessing Spatial Learning and Memory in Rodents

PubMed Central

Vorhees, Charles V.; Williams, Michael T.

2014-01-01

Maneuvering safely through the environment is central to survival of almost all species. The ability to do this depends on learning and remembering locations. This capacity is encoded in the brain by two systems: one using cues outside the organism (distal cues), allocentric navigation, and one using self-movement, internal cues and nearby proximal cues, egocentric navigation. Allocentric navigation involves the hippocampus, entorhinal cortex, and surrounding structures; in humans this system encodes allocentric, semantic, and episodic memory. This form of memory is assessed in laboratory animals in many ways, but the dominant form of assessment is the Morris water maze (MWM). Egocentric navigation involves the dorsal striatum and connected structures; in humans this system encodes routes and integrated paths and, when overlearned, becomes procedural memory. In this article, several allocentric assessment methods for rodents are reviewed and compared with the MWM. MWM advantages (little training required, no food deprivation, ease of testing, rapid and reliable learning, insensitivity to differences in body weight and appetite, absence of nonperformers, control methods for proximal cue learning, and performance effects) and disadvantages (concern about stress, perhaps not as sensitive for working memory) are discussed. Evidence-based design improvements and testing methods are reviewed for both rats and mice. Experimental factors that apply generally to spatial navigation and to MWM specifically are considered. It is concluded that, on balance, the MWM has more advantages than disadvantages and compares favorably with other allocentric navigation tasks. PMID:25225309

Control of forward swept wing configurations dominated by flight-dynamic/aeroelastic interactions

NASA Technical Reports Server (NTRS)

Rimer, M.; Chipman, R.; Muniz, B.

1984-01-01

An active control system concept for an aeroelastic wind-tunnel model of a statically unstable FSW configuration with wing-mounted stores is developed to provide acceptable longitudinal flying qualities while maintaining adequate flutter speed margin. On FSW configurations, the inherent aeroelastic wing divergence tendency causes strong flight-dynamic/aeroelastic interactions that in certain cases can produce a dynamic instability known as body-freedom flutter (BFF). The carriage of wing-mounted stores is shown to severely aggravate this problem. The control system developed combines a canard-based SAS with an Active Divergence/Flutter Suppression (ADFS) system which relies on wing-mounted sensors and a trailing-edge device (flaperon). Synergism between these two systems is exploited to obtain the flying qualities and flutter speed objectives.

A noninterference blade vibration measurement system for gas turbine engines

NASA Astrophysics Data System (ADS)

Watkins, William B.; Chi, Ray M.

1987-06-01

A noninterfering blade vibration system has been demonstrated in tests of a gas turbine first stage fan. Conceptual design of the system, including its theory, design of case mounted probes, and data acquisition and signal processing hardware was done in a previous effort. The current effort involved instrumentation of an engine fan stage with strain gages; data acquisition using shaft-mounted reference and case-mounted optical probes; recording of data on a wideband tape recorder; and posttest processing using off-line analysis in a facility computer and a minicomputer-based readout system designed for near- real-time readout. Results are presented in terms of true blade vibration frequencies, time and frequency dependent vibration amplitudes and comparison of the optical noninterference results with strain gage readings.

Center pivot mounted infrared sensors: Retrieval of ET and interface with satellite systems

USDA-ARS?s Scientific Manuscript database

Infrared sensors mounted aboard cener pivot irrigation systems can remotely sense the surface temperatures of the crops and soils, which provides important information on crop water status. This can be used for irrigation management and irrigation automation, which can increase crop water productivi...

Video monitoring system for car seat

NASA Technical Reports Server (NTRS)

Elrod, Susan Vinz (Inventor); Dabney, Richard W. (Inventor)

2004-01-01

A video monitoring system for use with a child car seat has video camera(s) mounted in the car seat. The video images are wirelessly transmitted to a remote receiver/display encased in a portable housing that can be removably mounted in the vehicle in which the car seat is installed.

Pyrogasification of blended animal manures to produce combustable gas and biochar

USDA-ARS?s Scientific Manuscript database

The objective of this study is to evaluate the efficiency of a skid-mounted pyrogasificaiton system for producing combustible gas from from animal manures: chicken litter, swine solids, and swine solids blended with rye grass. The skid-mounted pyrolysis system by the US Innovation Group, Inc. (USIG,...

Stable wafer-carrier system

DOEpatents

Rozenzon, Yan; Trujillo, Robert T; Beese, Steven C

2013-10-22

One embodiment of the present invention provides a wafer-carrier system used in a deposition chamber for carrying wafers. The wafer-carrier system includes a base susceptor and a top susceptor nested inside the base susceptor with its wafer-mounting side facing the base susceptor's wafer-mounting side, thereby forming a substantially enclosed narrow channel. The base susceptor provides an upward support to the top susceptor.

Retrieval cues that trigger reconsolidation of associative fear memory are not necessarily an exact replica of the original learning experience.

PubMed

Soeter, Marieke; Kindt, Merel

2015-01-01

Disrupting the process of memory reconsolidation may point to a novel therapeutic strategy for the permanent reduction of fear in patients suffering from anxiety disorders. However both in animal and human studies the retrieval cue typically involves a re-exposure to the original fear-conditioned stimulus (CS). A relevant question is whether abstract cues not directly associated with the threat event also trigger reconsolidation, given that anxiety disorders often result from vicarious or unobtrusive learning for which no explicit memory exists. Insofar as the fear memory involves a flexible representation of the original learning experience, we hypothesized that the process of memory reconsolidation may also be triggered by abstract cues. We addressed this hypothesis by using a differential human fear-conditioning procedure in two distinct fear-learning groups. We predicted that if fear learning involves discrimination on basis of perceptual cues within one semantic category (i.e., the perceptual-learning group, n = 15), the subsequent ambiguity of the abstract retrieval cue would not trigger memory reconsolidation. In contrast, if fear learning involves discriminating between two semantic categories (i.e., categorical-learning group, n = 15), an abstract retrieval cue would unequivocally reactivate the fear memory and might subsequently trigger memory reconsolidation. Here we show that memory reconsolidation may indeed be triggered by another cue than the one that was present during the original learning occasion, but this effect depends on the learning history. Evidence for fear memory reconsolidation was inferred from the fear-erasing effect of one pill of propranolol (40 mg) systemically administered upon exposure to the abstract retrieval cue. Our finding that reconsolidation of a specific fear association does not require exposure to the original retrieval cue supports the feasibility of reconsolidation-based interventions for emotional disorders.

Dopamine receptor blockade attenuates the general incentive motivational effects of noncontingently delivered rewards and reward-paired cues without affecting their ability to bias action selection.

PubMed

Ostlund, Sean B; Maidment, Nigel T

2012-01-01

Environmental cues affect our behavior in a variety of ways. Despite playing an invaluable role in guiding our daily activities, such cues also appear to trigger the harmful, compulsive behaviors that characterize addiction and other disorders of behavioral control. In instrumental conditioning, rewards and reward-paired cues bias action selection and invigorate reward-seeking behaviors, and appear to do so through distinct neurobehavioral processes. Although reward-paired cues are known to invigorate performance through a dopamine-dependent incentive motivational process, it is not known if dopamine also mediates the influence of rewards and reward-paired cues over action selection. The current study contrasted the effects of systemic administration of the nonspecific dopamine receptor antagonist flupentixol on response invigoration and action bias in Pavlovian-instrumental transfer, a test of cue-elicited responding, and in instrumental reinstatement, a test of noncontingent reward-elicited responding. Hungry rats were trained on two different stimulus-outcome relationships (eg, tone-grain pellets and noise-sucrose solution) and two different action-outcome relationships (eg, left press-grain and right press-sucrose). At test, we found that flupentixol pretreatment blocked the response invigoration generated by the cues but spared their ability to bias action selection to favor the action whose outcome was signaled by the cue being presented. The response-biasing influence of noncontingent reward deliveries was also unaffected by flupentixol. Interestingly, although flupentixol had a modest effect on the immediate response invigoration produced by those rewards, it was particularly potent in countering the lingering enhancement of responding produced by multiple reward deliveries. These findings indicate that dopamine mediates the general incentive motivational effects of noncontingent rewards and reward-paired cues but does not support their ability to bias action selection.

Sound arithmetic: auditory cues in the rehabilitation of impaired fact retrieval.

PubMed

Domahs, Frank; Zamarian, Laura; Delazer, Margarete

2008-04-01

The present single case study describes the rehabilitation of an acquired impairment of multiplication fact retrieval. In addition to a conventional drill approach, one set of problems was preceded by auditory cues while the other half was not. After extensive repetition, non-specific improvements could be observed for all trained problems (e.g., 3 * 7) as well as for their non-trained complementary problems (e.g., 7 * 3). Beyond this general improvement, specific therapy effects were found for problems trained with auditory cues. These specific effects were attributed to an involvement of implicit memory systems and/or attentional processes during training. Thus, the present results demonstrate that cues in the training of arithmetic facts do not have to be visual to be effective.

Alerting prefixes for speech warning messages. [in helicopters

NASA Technical Reports Server (NTRS)

Bucher, N. M.; Voorhees, J. W.; Karl, R. L.; Werner, E.

1984-01-01

A major question posed by the design of an integrated voice information display/warning system for next-generation helicopter cockpits is whether an alerting prefix should precede voice warning messages; if so, the characteristics desirable in such a cue must also be addressed. Attention is presently given to the results of a study which ascertained pilot response time and response accuracy to messages preceded by either neutral cues or the cognitively appropriate semantic cues. Both verbal cues and messages were spoken in direct, phoneme-synthesized speech, and a training manipulation was included to determine the extent to which previous exposure to speech thus produced facilitates these messages' comprehension. Results are discussed in terms of the importance of human factors research in cockpit display design.

Effects of motion base and g-seat cueing of simulator pilot performance

NASA Technical Reports Server (NTRS)

Ashworth, B. R.; Mckissick, B. T.; Parrish, R. V.

1984-01-01

In order to measure and analyze the effects of a motion plus g-seat cueing system, a manned-flight-simulation experiment was conducted utilizing a pursuit tracking task and an F-16 simulation model in the NASA Langley visual/motion simulator. This experiment provided the information necessary to determine whether motion and g-seat cues have an additive effect on the performance of this task. With respect to the lateral tracking error and roll-control stick force, the answer is affirmative. It is shown that presenting the two cues simultaneously caused significant reductions in lateral tracking error and that using the g-seat and motion base separately provided essentially equal reductions in the pilot's lateral tracking error.

Modeling Fault Diagnosis Performance on a Marine Powerplant Simulator.

DTIC Science & Technology

1985-08-01

two definitions are very similar. They emphasize that fidelity is a two dimensional -:oncept. They also pointed out the measurement prob- lems. Tasks...simulator duplicares cne enscr-: ztimulation, 4. . rnamic motion cues , visual :ues, ec. ?svcno ogicai fidelity is simply the degree to which the trainee...functions is only acceptable if the performance is paced by tne system, i.e., cues from the system serve to initiate elementary, skilled sub-routines

Revise and resubmit: How real-time parsing limitations influence grammar acquisition

PubMed Central

Pozzan, Lucia; Trueswell, John C.

2015-01-01

We present the results from a three-day artificial language learning study on adults. The study examined whether sentence-parsing limitations, in particular, difficulties revising initial syntactic/semantic commitments during comprehension, shape learners’ ability to acquire a language. Findings show that both comprehension and production of morphology pertaining to sentence argument structure are delayed when this morphology consistently appears at the end, rather than at the beginning, of sentences in otherwise identical grammatical systems. This suggests that real-time processing constraints impact acquisition; morphological cues that tend to guide linguistic analyses are easier to learn than cues that revise these analyses. Parallel performance in production and comprehension indicates that parsing constraints affect grammatical acquisition, not just real-time commitments. Properties of the linguistic system (e.g., ordering of cues within a sentence) interact with the properties of the cognitive system (cognitive control and conflict-resolution abilities) and together affect language acquisition. PMID:26026607

Dorsolateral striatal lesions impair navigation based on landmark-goal vectors but facilitate spatial learning based on a “cognitive map”

PubMed Central

Poulter, Steven L.; Austen, Joe M.

2015-01-01

In three experiments, the nature of the interaction between multiple memory systems in rats solving a variation of a spatial task in the water maze was investigated. Throughout training rats were able to find a submerged platform at a fixed distance and direction from an intramaze landmark by learning a landmark-goal vector. Extramaze cues were also available for standard place learning, or “cognitive mapping,” but these cues were valid only within each session, as the position of the platform moved around the pool between sessions together with the intramaze landmark. Animals could therefore learn the position of the platform by taking the consistent vector from the landmark across sessions or by rapidly encoding the new platform position on each session with reference to the extramaze cues. Excitotoxic lesions of the dorsolateral striatum impaired vector-based learning but facilitated cognitive map-based rapid place learning when the extramaze cues were relatively poor (Experiment 1) but not when they were more salient (Experiments 2 and 3). The way the lesion effects interacted with cue availability is consistent with the idea that the memory systems involved in the current navigation task are functionally cooperative yet associatively competitive in nature. PMID:25691518

Combat vehicle crew helmet-mounted display: next generation high-resolution head-mounted display

NASA Astrophysics Data System (ADS)

Nelson, Scott A.

1994-06-01

The Combat Vehicle Crew Head-Mounted Display (CVC HMD) program is an ARPA-funded, US Army Natick Research, Development, and Engineering Center monitored effort to develop a high resolution, flat panel HMD for the M1 A2 Abrams main battle tank. CVC HMD is part of the ARPA High Definition Systems (HDS) thrust to develop and integrate small (24 micrometers square pels), high resolution (1280 X 1024 X 6-bit grey scale at 60 frame/sec) active matrix electroluminescent (AMEL) and active matrix liquid crystal displays (AMLCD) for head mounted and projection applications. The Honeywell designed CVC HMD is a next generation head-mounted display system that includes advanced flat panel image sources, advanced digital display driver electronics, high speed (> 1 Gbps) digital interconnect electronics, and light weight, high performance optical and mechanical designs. The resulting dramatic improvements in size, weight, power, and cost have already led to program spin offs for both military and commercial applications.

The Effects of Attention Cueing on Visualizers' Multimedia Learning

ERIC Educational Resources Information Center

Yang, Hui-Yu

2016-01-01

The present study examines how various types of attention cueing and cognitive preference affect learners' comprehension of a cardiovascular system and cognitive load. EFL learners were randomly assigned to one of four conditions: non-signal, static-blood-signal, static-blood-static-arrow-signal, and animation-signal. The results indicated that…

Integration of a vision-based tracking platform, visual instruction, and error analysis models for an efficient billiard training system

NASA Astrophysics Data System (ADS)

Shih, Chihhsiong; Hsiung, Pao-Ann; Wan, Chieh-Hao; Koong, Chorng-Shiuh; Liu, Tang-Kun; Yang, Yuanfan; Lin, Chu-Hsing; Chu, William Cheng-Chung

2009-02-01

A billiard ball tracking system is designed to combine with a visual guide interface to instruct users for a reliable strike. The integrated system runs on a PC platform. The system makes use of a vision system for cue ball, object ball and cue stick tracking. A least-squares error calibration process correlates the real-world and the virtual-world pool ball coordinates for a precise guidance line calculation. Users are able to adjust the cue stick on the pool table according to a visual guidance line instruction displayed on a PC monitor. The ideal visual guidance line extended from the cue ball is calculated based on a collision motion analysis. In addition to calculating the ideal visual guide, the factors influencing selection of the best shot among different object balls and pockets are explored. It is found that a tolerance angle around the ideal line for the object ball to roll into a pocket determines the difficulty of a strike. This angle depends in turn on the distance from the pocket to the object, the distance from the object to the cue ball, and the angle between these two vectors. Simulation results for tolerance angles as a function of these quantities are given. A selected object ball was tested extensively with respect to various geometrical parameters with and without using our integrated system. Players with different proficiency levels were selected for the experiment. The results indicate that all players benefit from our proposed visual guidance system in enhancing their skills, while low-skill players show the maximum enhancement in skill with the help of our system. All exhibit enhanced maximum and average hit-in rates. Experimental results on hit-in rates have shown a pattern consistent with that of the analysis. The hit-in rate is thus tightly connected with the analyzed tolerance angles for sinking object balls into a target pocket. These results prove the efficiency of our system, and the analysis results can be used to attain an efficient game-playing strategy.

Cytoplasmic Copper Detoxification in Salmonella Can Contribute to SodC Metalation but Is Dispensable during Systemic Infection

PubMed Central

Fenlon, Luke A.

2017-01-01

ABSTRACT Salmonella enterica serovar Typhimurium is a leading cause of foodborne disease worldwide. Severe infections result from the ability of S. Typhimurium to survive within host immune cells, despite being exposed to various host antimicrobial factors. SodCI, a copper-zinc-cofactored superoxide dismutase, is required to defend against phagocytic superoxide. SodCII, an additional periplasmic superoxide dismutase, although produced during infection, does not function in the host. Previous studies suggested that CueP, a periplasmic copper binding protein, facilitates acquisition of copper by SodCII. CopA and GolT, both inner membrane ATPases that pump copper from the cytoplasm to the periplasm, are a source of copper for CueP. Using in vitro SOD assays, we found that SodCI can also utilize CueP to acquire copper. However, both SodCI and SodCII have a significant fraction of activity independent of CueP and cytoplasmic copper export. We utilized a series of mouse competition assays to address the in vivo role of CueP-mediated SodC activation. A copA golT cueP triple mutant was equally as competitive as the wild type, suggesting that sufficient SodCI is active to defend against phagocytic superoxide independent of CueP and cytoplasmic copper export. We also confirmed that a strain containing a modified SodCII, which is capable of complementing a sodCI deletion, was fully virulent in a copA golT cueP background competed against the wild type. These competitions also address the potential impact of cytoplasmic copper toxicity within the phagosome. Our data suggest that Salmonella does not encounter inhibitory concentrations of copper during systemic infection. IMPORTANCE Salmonella is a leading cause of gastrointestinal disease worldwide. In severe cases, Salmonella can cause life-threatening systemic infections, particularly in very young children, the elderly, or people who are immunocompromised. To cause disease, Salmonella must survive the hostile environment inside host immune cells, a location in which most bacteria are killed. Our work examines how one particular metal, copper, is acquired by Salmonella to activate a protein important for survival within immune cells. At high levels, copper itself can inhibit Salmonella. Using a strain of Salmonella that cannot detoxify intracellular copper, we also addressed the in vivo role of copper as an antimicrobial agent. PMID:28924031

Cytoplasmic Copper Detoxification in Salmonella Can Contribute to SodC Metalation but Is Dispensable during Systemic Infection.

PubMed

Fenlon, Luke A; Slauch, James M

2017-12-15

Salmonella enterica serovar Typhimurium is a leading cause of foodborne disease worldwide. Severe infections result from the ability of S Typhimurium to survive within host immune cells, despite being exposed to various host antimicrobial factors. SodCI, a copper-zinc-cofactored superoxide dismutase, is required to defend against phagocytic superoxide. SodCII, an additional periplasmic superoxide dismutase, although produced during infection, does not function in the host. Previous studies suggested that CueP, a periplasmic copper binding protein, facilitates acquisition of copper by SodCII. CopA and GolT, both inner membrane ATPases that pump copper from the cytoplasm to the periplasm, are a source of copper for CueP. Using in vitro SOD assays, we found that SodCI can also utilize CueP to acquire copper. However, both SodCI and SodCII have a significant fraction of activity independent of CueP and cytoplasmic copper export. We utilized a series of mouse competition assays to address the in vivo role of CueP-mediated SodC activation. A copA golT cueP triple mutant was equally as competitive as the wild type, suggesting that sufficient SodCI is active to defend against phagocytic superoxide independent of CueP and cytoplasmic copper export. We also confirmed that a strain containing a modified SodCII, which is capable of complementing a sodCI deletion, was fully virulent in a copA golT cueP background competed against the wild type. These competitions also address the potential impact of cytoplasmic copper toxicity within the phagosome. Our data suggest that Salmonella does not encounter inhibitory concentrations of copper during systemic infection. IMPORTANCE Salmonella is a leading cause of gastrointestinal disease worldwide. In severe cases, Salmonella can cause life-threatening systemic infections, particularly in very young children, the elderly, or people who are immunocompromised. To cause disease, Salmonella must survive the hostile environment inside host immune cells, a location in which most bacteria are killed. Our work examines how one particular metal, copper, is acquired by Salmonella to activate a protein important for survival within immune cells. At high levels, copper itself can inhibit Salmonella Using a strain of Salmonella that cannot detoxify intracellular copper, we also addressed the in vivo role of copper as an antimicrobial agent. Copyright © 2017 American Society for Microbiology.

Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture.

PubMed

Cebrià, Francesc; Newmark, Phillip A

2005-08-01

Conserved axon guidance mechanisms are essential for proper wiring of the nervous system during embryogenesis; however, the functions of these cues in adults and during regeneration remain poorly understood. Because freshwater planarians can regenerate a functional central nervous system (CNS) from almost any portion of their body, they are useful models in which to study the roles of guidance cues during neural regeneration. Here, we characterize two netrin homologs and one netrin receptor family member from Schmidtea mediterranea. RNAi analyses indicate that Smed-netR (netrin receptor) and Smed-netrin2 are required for proper CNS regeneration and that Smed-netR may mediate the response to Smed-netrin2. Remarkably, Smed-netR and Smed-netrin2 are also required in intact planarians to maintain the proper patterning of the CNS. These results suggest a crucial role for guidance cues, not only in CNS regeneration but also in maintenance of neural architecture.

Tachistoscopic exposure and masking of real three-dimensional scenes

PubMed Central

Pothier, Stephen; Philbeck, John; Chichka, David; Gajewski, Daniel A.

2010-01-01

Although there are many well-known forms of visual cues specifying absolute and relative distance, little is known about how visual space perception develops at small temporal scales. How much time does the visual system require to extract the information in the various absolute and relative distance cues? In this article, we describe a system that may be used to address this issue by presenting brief exposures of real, three-dimensional scenes, followed by a masking stimulus. The system is composed of an electronic shutter (a liquid crystal smart window) for exposing the stimulus scene, and a liquid crystal projector coupled with an electromechanical shutter for presenting the masking stimulus. This system can be used in both full- and reduced-cue viewing conditions, under monocular and binocular viewing, and at distances limited only by the testing space. We describe a configuration that may be used for studying the microgenesis of visual space perception in the context of visually directed walking. PMID:19182129

Man-systems evaluation of moving base vehicle simulation motion cues. [human acceleration perception involving visual feedback

NASA Technical Reports Server (NTRS)

Kirkpatrick, M.; Brye, R. G.

1974-01-01

A motion cue investigation program is reported that deals with human factor aspects of high fidelity vehicle simulation. General data on non-visual motion thresholds and specific threshold values are established for use as washout parameters in vehicle simulation. A general purpose similator is used to test the contradictory cue hypothesis that acceleration sensitivity is reduced during a vehicle control task involving visual feedback. The simulator provides varying acceleration levels. The method of forced choice is based on the theory of signal detect ability.

Research on integration of visual and motion cues for flight simulation and ride quality investigation

NASA Technical Reports Server (NTRS)

Young, L. R.; Oman, C. M.; Curry, R. E.

1977-01-01

Vestibular perception and integration of several sensory inputs in simulation were studied. The relationship between tilt sensation induced by moving fields and those produced by actual body tilt is discussed. Linearvection studies were included and the application of the vestibular model for perception of orientation based on motion cues is presented. Other areas of examination includes visual cues in approach to landing, and a comparison of linear and nonlinear wash out filters using a model of the human vestibular system is given.

47 CFR 15.253 - Operation within the bands 46.7-46.9 GHz and 76.0-77.0 GHz.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-77.0 GHz is restricted to vehicle-mounted field disturbance sensors used as vehicle radar systems... operation is as a vehicle-mounted field disturbance sensor. Operation under the provisions of this section...-mounted field disturbance sensors, if the vehicle is in motion the power density of any emission within...

Validation of the i-STAT and HemoCue systems for the analysis of blood parameters in the bar-headed goose, Anser indicus

PubMed Central

Harter, T. S.; Reichert, M.; Brauner, C. J.; Milsom, W. K.

2015-01-01

Every year, bar-headed geese (Anser indicus) perform some of the most remarkable trans-Himalayan migrations, and researchers are increasingly interested in understanding the physiology underlying their high-altitude flight performance. A major challenge is generating reliable measurements of blood parameters on wild birds in the field, where established analytical techniques are often not available. Therefore, we validated two commonly used portable clinical analysers (PCAs), the i-STAT and the HemoCue systems, for the analysis of blood parameters in bar-headed geese. The pH, partial pressures of O2 and CO2 (PO2 and PCO2), haemoglobin O2 saturation (sO2), haematocrit (Hct) and haemoglobin concentration [Hb] were simultaneously measured with the two PCA systems (i-STAT for all parameters; HemoCue for [Hb]) and with conventional laboratory techniques over a physiological range of PO2, PCO2 and Hct. Our results indicate that the i-STAT system can generate reliable values on bar-headed goose whole blood pH, PO2, PCO2 and Hct, but we recommend correcting the obtained values using the linear equations determined here for higher accuracy. The i-STAT is probably not able to produce meaningful measurements of sO2 and [Hb] over a range of physiologically relevant environmental conditions. However, we can recommend the use of the HemoCue to measure [Hb] in the bar-headed goose, if results are corrected. We emphasize that the equations that we provide to correct PCA results are applicable only to bar-headed goose whole blood under the conditions that we tested. We encourage researchers to validate i-STAT or HemoCue results thoroughly for their specific study conditions and species in order to yield accurate results. PMID:27293706

Female sea lamprey shift orientation toward a conspecific chemical cue to escape a sensory trap

USGS Publications Warehouse

Brant, Cory O.; Johnson, Nicholas; Li, Ke; Buchinger, Tyler J.; Li, Weiming

2016-01-01

The sensory trap model of signal evolution hypothesizes that signalers adapt to exploit a cue used by the receiver in another context. Although exploitation of receiver biases can result in conflict between the sexes, deceptive signaling systems that are mutually beneficial drive the evolution of stable communication systems. However, female responses in the nonsexual and sexual contexts may become uncoupled if costs are associated with exhibiting a similar response to a trait in both contexts. Male sea lamprey (Petromyzon marinus) signal with a mating pheromone, 3-keto petromyzonol sulfate (3kPZS), which may be a match to a juvenile cue used by females during migration. Upstream movement of migratory lampreys is partially guided by 3kPZS, but females only move toward 3kPZS with proximal accuracy during spawning. Here, we use in-stream behavioral assays paired with gonad histology to document the transition of female preference for juvenile- and male-released 3kPZS that coincides with the functional shift of 3kPZS as a migratory cue to a mating pheromone. Females became increasingly biased toward the source of synthesized 3kPZS as their maturation progressed into the reproductive phase, at which point, a preference for juvenile odor (also containing 3kPZS naturally) ceased to exist. Uncoupling of female responses during migration and spawning makes the 3kPZS communication system a reliable means of synchronizing mate search. The present study offers a rare example of a transition in female responses to a chemical cue between nonsexual and sexual contexts, provides insights into the origins of stable communication signaling systems.

Spatial Attention, Motor Intention, and Bayesian Cue Predictability in the Human Brain.

PubMed

Kuhns, Anna B; Dombert, Pascasie L; Mengotti, Paola; Fink, Gereon R; Vossel, Simone

2017-05-24

Predictions about upcoming events influence how we perceive and respond to our environment. There is increasing evidence that predictions may be generated based upon previous observations following Bayesian principles, but little is known about the underlying cortical mechanisms and their specificity for different cognitive subsystems. The present study aimed at identifying common and distinct neural signatures of predictive processing in the spatial attentional and motor intentional system. Twenty-three female and male healthy human volunteers performed two probabilistic cueing tasks with either spatial or motor cues while lying in the fMRI scanner. In these tasks, the percentage of cue validity changed unpredictably over time. Trialwise estimates of cue predictability were derived from a Bayesian observer model of behavioral responses. These estimates were included as parametric regressors for analyzing the BOLD time series. Parametric effects of cue predictability in valid and invalid trials were considered to reflect belief updating by precision-weighted prediction errors. The brain areas exhibiting predictability-dependent effects dissociated between the spatial attention and motor intention task, with the right temporoparietal cortex being involved during spatial attention and the left angular gyrus and anterior cingulate cortex during motor intention. Connectivity analyses revealed that all three areas showed predictability-dependent coupling with the right hippocampus. These results suggest that precision-weighted prediction errors of stimulus locations and motor responses are encoded in distinct brain regions, but that crosstalk with the hippocampus may be necessary to integrate new trialwise outcomes in both cognitive systems. SIGNIFICANCE STATEMENT The brain is able to infer the environments' statistical structure and responds strongly to expectancy violations. In the spatial attentional domain, it has been shown that parts of the attentional networks are sensitive to the predictability of stimuli. It remains unknown, however, whether these effects are ubiquitous or if they are specific for different cognitive systems. The present study compared the influence of model-derived cue predictability on brain activity in the spatial attentional and motor intentional system. We identified areas with distinct predictability-dependent activation for spatial attention and motor intention, but also common connectivity changes of these regions with the hippocampus. These findings provide novel insights into the generality and specificity of predictive processing signatures in the human brain. Copyright © 2017 the authors 0270-6474/17/375334-11$15.00/0.

Top-mounted inlet system feasibility for transonic-supersonic fighter aircraft. [V/STOL aircraft

NASA Technical Reports Server (NTRS)

Williams, T. L.; Hunt, B. L.; Smeltzer, D. B.; Nelms, W. P.

1981-01-01

The more salient findings are presented of recent top inlet performance evaluations aimed at assessing the feasibility of top-mounted inlet systems for transonic-supersonic fighter aircraft applications. Top inlet flow field and engine-inlet performance test data show the influence of key aircraft configuration variables-inlet longitudinal position, wing leading-edge extension planform area, canopy-dorsal integration, and variable incidence canards-on top inlet performance over the Mach range of 0.6 to 2.0. Top inlet performance data are compared with those or more conventional inlet/airframe integrations in an effort to assess the viability of top-mounted inlet systems relative to conventional inlet installations.

A designated odor-language integration system in the human brain.

PubMed

Olofsson, Jonas K; Hurley, Robert S; Bowman, Nicholas E; Bao, Xiaojun; Mesulam, M-Marsel; Gottfried, Jay A

2014-11-05

Odors are surprisingly difficult to name, but the mechanism underlying this phenomenon is poorly understood. In experiments using event-related potentials (ERPs) and functional magnetic resonance imaging (fMRI), we investigated the physiological basis of odor naming with a paradigm where olfactory and visual object cues were followed by target words that either matched or mismatched the cue. We hypothesized that word processing would not only be affected by its semantic congruency with the preceding cue, but would also depend on the cue modality (olfactory or visual). Performance was slower and less precise when linking a word to its corresponding odor than to its picture. The ERP index of semantic incongruity (N400), reflected in the comparison of nonmatching versus matching target words, was more constrained to posterior electrode sites and lasted longer on odor-cue (vs picture-cue) trials. In parallel, fMRI cross-adaptation in the right orbitofrontal cortex (OFC) and the left anterior temporal lobe (ATL) was observed in response to words when preceded by matching olfactory cues, but not by matching visual cues. Time-series plots demonstrated increased fMRI activity in OFC and ATL at the onset of the odor cue itself, followed by response habituation after processing of a matching (vs nonmatching) target word, suggesting that predictive perceptual representations in these regions are already established before delivery and deliberation of the target word. Together, our findings underscore the modality-specific anatomy and physiology of object identification in the human brain. Copyright © 2014 the authors 0270-6474/14/3414864-10$15.00/0.

Automatic Mechanisms for Social Attention Are Culturally Penetrable.

PubMed

Cohen, Adam S; Sasaki, Joni Y; German, Tamsin C; Kim, Heejung S

2017-01-01

Are mechanisms for social attention influenced by culture? Evidence that social attention is triggered automatically by bottom-up gaze cues and is uninfluenced by top-down verbal instructions may suggest it operates in the same way everywhere. Yet considerations from evolutionary and cultural psychology suggest that specific aspects of one's cultural background may have consequence for the way mechanisms for social attention develop and operate. In more interdependent cultures, the scope of social attention may be broader, focusing on more individuals and relations between those individuals. We administered a multi-gaze cueing task requiring participants to fixate a foreground face flanked by background faces and measured shifts in attention using eye tracking. For European Americans, gaze cueing did not depend on the direction of background gaze cues, suggesting foreground gaze alone drives automatic attention shifting; for East Asians, cueing patterns differed depending on whether the foreground cue matched or mismatched background cues, suggesting foreground and background gaze information were integrated. These results demonstrate that cultural background influences the social attention system by shifting it into a narrow or broad mode of operation and, importantly, provides evidence challenging the assumption that mechanisms underlying automatic social attention are necessarily rigid and impenetrable to culture. Copyright © 2015 Cognitive Science Society, Inc.

The polarization compass dominates over idiothetic cues in path integration of desert ants.

PubMed

Lebhardt, Fleur; Koch, Julja; Ronacher, Bernhard

2012-02-01

Desert ants, Cataglyphis, use the sky's pattern of polarized light as a compass reference for navigation. However, they do not fully exploit the complexity of this pattern, rather - as proposed previously - they assess their walking direction by means of an approximate solution based on a simplified internal template. Approximate rules are error-prone. We therefore asked whether the ants use additional cues to improve the accuracy of directional decisions, and focused on 'idiothetic' cues, i.e. cues based on information from proprioceptors. We trained ants in a channel system that was covered with a polarization filter, providing only a single e-vector direction as a directional 'celestial' cue. Then we observed their homebound runs on a test field, allowing full view of the sky. In crucial experiments, the ants were exposed to a cue conflict, in which sky compass and idiothetic information disagreed, by training them in a straight channel that provided a change in e-vector direction. The results indicated that the polarization information completely dominates over idiothetic cues. Two path segments with different e-vector orientations are combined linearly to a summed home vector. Our data provide additional evidence that Cataglyphis uses a simplified internal template to derive directional information from the sky's polarization pattern.

Common mechanisms of spatial attention in memory and perception: a tactile dual-task study.

PubMed

Katus, Tobias; Andersen, Søren K; Müller, Matthias M

2014-03-01

Orienting attention to locations in mnemonic representations engages processes that functionally and anatomically overlap the neural circuitry guiding prospective shifts of spatial attention. The attention-based rehearsal account predicts that the requirement to withdraw attention from a memorized location impairs memory accuracy. In a dual-task study, we simultaneously presented retro-cues and pre-cues to guide spatial attention in short-term memory (STM) and perception, respectively. The spatial direction of each cue was independent of the other. The locations indicated by the combined cues could be compatible (same hand) or incompatible (opposite hands). Incompatible directional cues decreased lateralized activity in brain potentials evoked by visual cues, indicating interference in the generation of prospective attention shifts. The detection of external stimuli at the prospectively cued location was impaired when the memorized location was part of the perceptually ignored hand. The disruption of attention-based rehearsal by means of incompatible pre-cues reduced memory accuracy and affected encoding of tactile test stimuli at the retrospectively cued hand. These findings highlight the functional significance of spatial attention for spatial STM. The bidirectional interactions between both tasks demonstrate that spatial attention is a shared neural resource of a capacity-limited system that regulates information processing in internal and external stimulus representations.

The association between reading abilities and visual-spatial attention in Hong Kong Chinese children.

PubMed

Liu, Sisi; Liu, Duo; Pan, Zhihui; Xu, Zhengye

2018-03-25

A growing body of research suggests that visual-spatial attention is important for reading achievement. However, few studies have been conducted in non-alphabetic orthographies. This study extended the current research to reading development in Chinese, a logographic writing system known for its visual complexity. Eighty Hong Kong Chinese children were selected and divided into poor reader and typical reader groups, based on their performance on the measures of reading fluency, Chinese character reading, and reading comprehension. The poor and typical readers were matched on age and nonverbal intelligence. A Posner's spatial cueing task was adopted to measure the exogenous and endogenous orienting of visual-spatial attention. Although the typical readers showed the cueing effect in the central cue condition (i.e., responses to targets following valid cues were faster than those to targets following invalid cues), the poor readers did not respond differently in valid and invalid conditions, suggesting an impairment of the endogenous orienting of attention. The two groups, however, showed a similar cueing effect in the peripheral cue condition, indicating intact exogenous orienting in the poor readers. These findings generally supported a link between the orienting of covert attention and Chinese reading, providing evidence for the attentional-deficit theory of dyslexia. Copyright © 2018 John Wiley & Sons, Ltd.

Seeing by touch: evaluation of a soft biologically-inspired artificial fingertip in real-time active touch.

PubMed

Assaf, Tareq; Roke, Calum; Rossiter, Jonathan; Pipe, Tony; Melhuish, Chris

2014-02-07

Effective tactile sensing for artificial platforms remains an open issue in robotics. This study investigates the performance of a soft biologically-inspired artificial fingertip in active exploration tasks. The fingertip sensor replicates the mechanisms within human skin and offers a robust solution that can be used both for tactile sensing and gripping/manipulating objects. The softness of the optical sensor's contact surface also allows safer interactions with objects. High-level tactile features such as edges are extrapolated from the sensor's output and the information is used to generate a tactile image. The work presented in this paper aims to investigate and evaluate this artificial fingertip for 2D shape reconstruction. The sensor was mounted on a robot arm to allow autonomous exploration of different objects. The sensor and a number of human participants were then tested for their abilities to track the raised perimeters of different planar objects and compared. By observing the technique and accuracy of the human subjects, simple but effective parameters were determined in order to evaluate the artificial system's performance. The results prove the capability of the sensor in such active exploration tasks, with a comparable performance to the human subjects despite it using tactile data alone whereas the human participants were also able to use proprioceptive cues.

A Self-Diagnostic System for the M6 Accelerometer

NASA Technical Reports Server (NTRS)

Flanagan, Patrick M.; Lekki, John

2001-01-01

The design of a Self-Diagnostic (SD) accelerometer system for the Space Shuttle Main Engine is presented. This retrofit system connects diagnostic electronic hardware and software to the current M6 accelerometer system. This paper discusses the general operation of the M6 accelerometer SD system and procedures for developing and evaluating the SD system. Signal processing techniques using M6 accelerometer diagnostic data are explained. Test results include diagnostic data responding to changing ambient temperature, mounting torque and base mounting impedance.

MOUNT SHASTA WILDERNESS STUDY AREA, CALIFORNIA.

USGS Publications Warehouse

Christiansen, Robert L.; Tuchek, Ernest T.

1984-01-01

The Mount Shasta Wilderness lies wholly on the slopes and summit area of Mount Shasta and consists almost entirely of the products of geologically young volcanism. Small deposits of volcanic cinders and pumice are present. The volcanic system of Mount Shasta is judged to have probable resource potential for geothermal energy but that potential is least within the wilderness study area boundaries. Because any geothermal energy resource beneath the volcano would lie at considerable depths, exploration or development would be most likely at lower altitudes on the gentler slopes outside the study area.

A Real-Time Optical 3D Tracker for Head-Mounted Display Systems

DTIC Science & Technology

1990-03-01

paper. OPTOTRAK [Nor88] uses one camera with two dual-axis CCD infrared position sensors. Each position sen- sor has a dedicated processor board to...enhance the use- [Nor88] Northern Digital. Trade literature on Optotrak fulness of head-mounted display systems. - Northern Digital’s Three Dimensional

4. PULLEY SYSTEM AND CABLE FOR GATELIFTING MECHANISM, MOUNTED ABOVE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. PULLEY SYSTEM AND CABLE FOR GATE-LIFTING MECHANISM, MOUNTED ABOVE THE THREE GATE OPENINGS, LOOKING SOUTH/SOUTHEAST. - Washington Water Power Spokane River Upper Falls Hydroelectric Development, Gates & Gate-Lifting Mechanisms, Spokane River, approximately 0.5 mile northeast of intersection of Spokane Falls Boulevard & Post Street, Spokane, Spokane County, WA

Power supply sharing in the Apollo telescope mount electrical power system

NASA Technical Reports Server (NTRS)

Lanier, R., Jr.; Kapustka, R.

1977-01-01

A modular dc power supply power sharing technique was developed for the Apollo telescope mount electrical power sytem on Skylab. The advantages and disadvantages of various techniques used are reviewed and compared. The new technique design is discussed, and results of its implementation in the power system are reviewed.

Peregrine System | High-Performance Computing | NREL

Science.gov Websites

) and longer-term (/projects) storage. These file systems are mounted on all nodes. Peregrine has three -2670 Xeon processors and 64 GB of memory. In addition to mounting the /home, /nopt, /projects and # cores/node Memory/node Peak (DP) performance per node 88 Intel Xeon E5-2670 "Sandy Bridge" 8

Base excitation testing system using spring elements to pivotally mount wind turbine blades

DOEpatents

Cotrell, Jason; Hughes, Scott; Butterfield, Sandy; Lambert, Scott

2013-12-10

A system (1100) for fatigue testing wind turbine blades (1102) through forced or resonant excitation of the base (1104) of a blade (1102). The system (1100) includes a test stand (1112) and a restoring spring assembly (1120) mounted on the test stand (1112). The restoring spring assembly (1120) includes a primary spring element (1124) that extends outward from the test stand (1112) to a blade mounting plate (1130) configured to receive a base (1104) of blade (1102). During fatigue testing, a supported base (1104) of a blad (1102) may be pivotally mounted to the test stand (1112) via the restoring spring assembly (1120). The system (1100) may include an excitation input assembly (1140) that is interconnected with the blade mouting plate (1130) to selectively apply flapwise, edgewise, and/or pitch excitation forces. The restoring spring assemply (1120) may include at least one tuning spring member (1127) positioned adjacent to the primary spring element (1124) used to tune the spring constant or stiffness of the primary spring element (1124) in one of the excitation directions.

A comparison of visuomotor cue integration strategies for object placement and prehension.

PubMed

Greenwald, Hal S; Knill, David C

2009-01-01

Visual cue integration strategies are known to depend on cue reliability and how rapidly the visual system processes incoming information. We investigated whether these strategies also depend on differences in the information demands for different natural tasks. Using two common goal-oriented tasks, prehension and object placement, we determined whether monocular and binocular information influence estimates of three-dimensional (3D) orientation differently depending on task demands. Both tasks rely on accurate 3D orientation estimates, but 3D position is potentially more important for grasping. Subjects placed an object on or picked up a disc in a virtual environment. On some trials, the monocular cues (aspect ratio and texture compression) and binocular cues (e.g., binocular disparity) suggested slightly different 3D orientations for the disc; these conflicts either were present upon initial stimulus presentation or were introduced after movement initiation, which allowed us to quantify how information from the cues accumulated over time. We analyzed the time-varying orientations of subjects' fingers in the grasping task and those of the object in the object placement task to quantify how different visual cues influenced motor control. In the first experiment, different subjects performed each task, and those performing the grasping task relied on binocular information more when orienting their hands than those performing the object placement task. When subjects in the second experiment performed both tasks in interleaved sessions, binocular cues were still more influential during grasping than object placement, and the different cue integration strategies observed for each task in isolation were maintained. In both experiments, the temporal analyses showed that subjects processed binocular information faster than monocular information, but task demands did not affect the time course of cue processing. How one uses visual cues for motor control depends on the task being performed, although how quickly the information is processed appears to be task invariant.

Winnebago Tribe Solar Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nieman, Autumn

2016-02-26

The strategy of the Solar Project was to reduce fuel use within two years by a roof mounted photovoltaic system. The police/fire building is completely powered by electricity. The renewable energy system we have selected has a power capacity of 23kW and the ability to export 44.3 MWh. We anticipate 32.55% kWh energy savings, an excess of the required 30% reduction, in the building’s total fuel use based on the most current 12 months of data (2012). The solar electric system is a grid-tie, ballast mounted on a flat roof over the police/fire station. The solar electric system includes 280more » Watt modules for a nominal total of 22.80 kW. Approximately 84 modules are ballast mounted to the flat roof facing south.« less

Payload isolation and stabilization by a Suspended Experiment Mount (SEM)

NASA Technical Reports Server (NTRS)

Bailey, Wayne L.; Desanctis, Carmine E.; Nicaise, Placide D.; Schultz, David N.

1992-01-01

Many Space Shuttle and Space Station payloads can benefit from isolation from crew or attitude control system disturbances. Preliminary studies have been performed for a Suspended Experiment Mount (SEM) system that will provide isolation from accelerations and stabilize the viewing direction of a payload. The concept consists of a flexible suspension system and payload-mounted control moment gyros. The suspension system, which is rigidly locked for ascent and descent, isolates the payload from high frequency disturbances. The control moment gyros stabilize the payload orientation. The SEM will be useful for payloads that require a lower-g environment than a manned vehicle can provide, such as materials processing, and for payloads that require stabilization of pointing direction, but not large angle slewing, such as nadir-viewing earth observation or solar viewing payloads.

Auditory and visual cueing modulate cycling speed of older adults and persons with Parkinson's disease in a Virtual Cycling (V-Cycle) system.

PubMed

Gallagher, Rosemary; Damodaran, Harish; Werner, William G; Powell, Wendy; Deutsch, Judith E

2016-08-19

Evidence based virtual environments (VEs) that incorporate compensatory strategies such as cueing may change motor behavior and increase exercise intensity while also being engaging and motivating. The purpose of this study was to determine if persons with Parkinson's disease and aged matched healthy adults responded to auditory and visual cueing embedded in a bicycling VE as a method to increase exercise intensity. We tested two groups of participants, persons with Parkinson's disease (PD) (n = 15) and age-matched healthy adults (n = 13) as they cycled on a stationary bicycle while interacting with a VE. Participants cycled under two conditions: auditory cueing (provided by a metronome) and visual cueing (represented as central road markers in the VE). The auditory condition had four trials in which auditory cues or the VE were presented alone or in combination. The visual condition had five trials in which the VE and visual cue rate presentation was manipulated. Data were analyzed by condition using factorial RMANOVAs with planned t-tests corrected for multiple comparisons. There were no differences in pedaling rates between groups for both the auditory and visual cueing conditions. Persons with PD increased their pedaling rate in the auditory (F 4.78, p = 0.029) and visual cueing (F 26.48, p < 0.000) conditions. Age-matched healthy adults also increased their pedaling rate in the auditory (F = 24.72, p < 0.000) and visual cueing (F = 40.69, p < 0.000) conditions. Trial-to-trial comparisons in the visual condition in age-matched healthy adults showed a step-wise increase in pedaling rate (p = 0.003 to p < 0.000). In contrast, persons with PD increased their pedaling rate only when explicitly instructed to attend to the visual cues (p < 0.000). An evidenced based cycling VE can modify pedaling rate in persons with PD and age-matched healthy adults. Persons with PD required attention directed to the visual cues in order to obtain an increase in cycling intensity. The combination of the VE and auditory cues was neither additive nor interfering. These data serve as preliminary evidence that embedding auditory and visual cues to alter cycling speed in a VE as method to increase exercise intensity that may promote fitness.

[Effects of odor cue on morphine-induced dependence and craving in mice].

PubMed

Liu, Xiao-Fen; Yang, Guang; Yang, Rui; Jia, Qiang; Guan, Su-Dong

2012-04-01

The olfactory system may play a pivotal role in drug addiction. To clarify the issues, we investigated the morphine dependence and psychological craving in morphine addicted mice using the conditioned place preference (CPP) paradigm by taking an only odor cue as the conditioned stimulus (CS). The results showed that by pairing morphine with odor, the CPP could be induced in mice. When the morphine addicted mice were exposed to a novel environment during morphine withdrawal, they spent significantly longer time in the chamber with morphine-paired odor than in the control chamber. The effects of odor cue on the morphine CPP were blocked by the administration of dopamine D1 or D2 antagonists. The studies indicated that olfactory system plays an important role in drug addiction.

Tackling the challenges of fully immersive head-mounted AR devices

NASA Astrophysics Data System (ADS)

Singer, Wolfgang; Hillenbrand, Matthias; Münz, Holger

2017-11-01

The optical requirements of fully immersive head mounted AR devices are inherently determined by the human visual system. The etendue of the visual system is large. As a consequence, the requirements for fully immersive head-mounted AR devices exceeds almost any high end optical system. Two promising solutions to achieve the large etendue and their challenges are discussed. Head-mounted augmented reality devices have been developed for decades - mostly for application within aircrafts and in combination with a heavy and bulky helmet. The established head-up displays for applications within automotive vehicles typically utilize similar techniques. Recently, there is the vision of eyeglasses with included augmentation, offering a large field of view, and being unobtrusively all-day wearable. There seems to be no simple solution to reach the functional performance requirements. Known technical solutions paths seem to be a dead-end, and some seem to offer promising perspectives, however with severe limitations. As an alternative, unobtrusively all-day wearable devices with a significantly smaller field of view are already possible.

The application of reduced-processing decision support systems to facilitate the acquisition of decision-making skills.

PubMed

Perry, Nathan C; Wiggins, Mark W; Childs, Merilyn; Fogarty, Gerard

2013-06-01

The study was designed to examine whether the availability of reduced-processing decision support system interfaces could improve the decision making of inexperienced personnel in the context of Although research into reduced-processing decision support systems has demonstrated benefits in minimizing cognitive load, these benefits have not typically translated into direct improvements in decision accuracy because of the tendency for inexperienced personnel to focus on less-critical information. The authors investigated whether reduced-processing interfaces that direct users' attention toward the most critical cues for decision making can produce improvements in decision-making performance. Novice participants made incident command-related decisions in experimental conditions that differed according to the amount of information that was available within the interface, the level of control that they could exert over the presentation of information, and whether they had received decision training. The results revealed that despite receiving training, participants improved in decision accuracy only when they were provided with an interface that restricted information access to the most critical cues. It was concluded that an interface that restricts information access to only the most critical cues in the scenario can facilitate improvements in decision performance. Decision support system interfaces that encourage the processing of the most critical cues have the potential to improve the accuracy and timeliness of decisions made by inexperienced personnel.

Attentional bias to food-related visual cues: is there a role in obesity?

PubMed

Doolan, K J; Breslin, G; Hanna, D; Gallagher, A M

2015-02-01

The incentive sensitisation model of obesity suggests that modification of the dopaminergic associated reward systems in the brain may result in increased awareness of food-related visual cues present in the current food environment. Having a heightened awareness of these visual food cues may impact on food choices and eating behaviours with those being most aware of or demonstrating greater attention to food-related stimuli potentially being at greater risk of overeating and subsequent weight gain. To date, research related to attentional responses to visual food cues has been both limited and conflicting. Such inconsistent findings may in part be explained by the use of different methodological approaches to measure attentional bias and the impact of other factors such as hunger levels, energy density of visual food cues and individual eating style traits that may influence visual attention to food-related cues outside of weight status alone. This review examines the various methodologies employed to measure attentional bias with a particular focus on the role that attentional processing of food-related visual cues may have in obesity. Based on the findings of this review, it appears that it may be too early to clarify the role visual attention to food-related cues may have in obesity. Results however highlight the importance of considering the most appropriate methodology to use when measuring attentional bias and the characteristics of the study populations targeted while interpreting results to date and in designing future studies.

Subconscious Visual Cues during Movement Execution Allow Correct Online Choice Reactions

PubMed Central

Leukel, Christian; Lundbye-Jensen, Jesper; Christensen, Mark Schram; Gollhofer, Albert; Nielsen, Jens Bo; Taube, Wolfgang

2012-01-01

Part of the sensory information is processed by our central nervous system without conscious perception. Subconscious processing has been shown to be capable of triggering motor reactions. In the present study, we asked the question whether visual information, which is not consciously perceived, could influence decision-making in a choice reaction task. Ten healthy subjects (28±5 years) executed two different experimental protocols. In the Motor reaction protocol, a visual target cue was shown on a computer screen. Depending on the displayed cue, subjects had to either complete a reaching movement (go-condition) or had to abort the movement (stop-condition). The cue was presented with different display durations (20–160 ms). In the second Verbalization protocol, subjects verbalized what they experienced on the screen. Again, the cue was presented with different display durations. This second protocol tested for conscious perception of the visual cue. The results of this study show that subjects achieved significantly more correct responses in the Motor reaction protocol than in the Verbalization protocol. This difference was only observed at the very short display durations of the visual cue. Since correct responses in the Verbalization protocol required conscious perception of the visual information, our findings imply that the subjects performed correct motor responses to visual cues, which they were not conscious about. It is therefore concluded that humans may reach decisions based on subconscious visual information in a choice reaction task. PMID:23049749

Musically cued gait-training improves both perceptual and motor timing in Parkinson's disease.

PubMed

Benoit, Charles-Etienne; Dalla Bella, Simone; Farrugia, Nicolas; Obrig, Hellmuth; Mainka, Stefan; Kotz, Sonja A

2014-01-01

It is well established that auditory cueing improves gait in patients with idiopathic Parkinson's disease (IPD). Disease-related reductions in speed and step length can be improved by providing rhythmical auditory cues via a metronome or music. However, effects on cognitive aspects of motor control have yet to be thoroughly investigated. If synchronization of movement to an auditory cue relies on a supramodal timing system involved in perceptual, motor, and sensorimotor integration, auditory cueing can be expected to affect both motor and perceptual timing. Here, we tested this hypothesis by assessing perceptual and motor timing in 15 IPD patients before and after a 4-week music training program with rhythmic auditory cueing. Long-term effects were assessed 1 month after the end of the training. Perceptual and motor timing was evaluated with a battery for the assessment of auditory sensorimotor and timing abilities and compared to that of age-, gender-, and education-matched healthy controls. Prior to training, IPD patients exhibited impaired perceptual and motor timing. Training improved patients' performance in tasks requiring synchronization with isochronous sequences, and enhanced their ability to adapt to durational changes in a sequence in hand tapping tasks. Benefits of cueing extended to time perception (duration discrimination and detection of misaligned beats in musical excerpts). The current results demonstrate that auditory cueing leads to benefits beyond gait and support the idea that coupling gait to rhythmic auditory cues in IPD patients relies on a neuronal network engaged in both perceptual and motor timing.

Slant Perception Under Stereomicroscopy.

PubMed

Horvath, Samantha; Macdonald, Kori; Galeotti, John; Klatzky, Roberta L

2017-11-01

Objective These studies used threshold and slant-matching tasks to assess and quantitatively measure human perception of 3-D planar images viewed through a stereomicroscope. The results are intended for use in developing augmented-reality surgical aids. Background Substantial research demonstrates that slant perception is performed with high accuracy from monocular and binocular cues, but less research concerns the effects of magnification. Viewing through a microscope affects the utility of monocular and stereo slant cues, but its impact is as yet unknown. Method Participants performed in a threshold slant-detection task and matched the slant of a tool to a surface. Different stimuli and monocular versus binocular viewing conditions were implemented to isolate stereo cues alone, stereo with perspective cues, accommodation cue only, and cues intrinsic to optical-coherence-tomography images. Results At magnification of 5x, slant thresholds with stimuli providing stereo cues approximated those reported for direct viewing, about 12°. Most participants (75%) who passed a stereoacuity pretest could match a tool to the slant of a surface viewed with stereo at 5x magnification, with mean compressive error of about 20% for optimized surfaces. Slant matching to optical coherence tomography images of the cornea viewed under the microscope was also demonstrated. Conclusion Despite the distortions and cue loss introduced by viewing under the stereomicroscope, most participants were able to detect and interact with slanted surfaces. Application The experiments demonstrated sensitivity to surface slant that supports the development of augmented-reality systems to aid microscope-aided surgery.

The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory.

PubMed

Monsey, Melissa S; Sanchez, Hayde; Taylor, Jane R

2017-02-01

Sustained abstinence from cocaine use is frequently compromised by exposure to environmental stimuli that have previously been strongly associated with drug taking. Such cues trigger memories of the effects of the drug, leading to craving and potential relapse. Our work has demonstrated that manipulating cocaine-cue memories by destabilizing them through interfering with the reconsolidation process is one potential therapeutic tool by which to prolong abstinence. Here, we examine the use of the naturally occurring amnestic agent garcinol to manipulate an established cocaine-cue memory. Rats underwent 12 days of cocaine self-administration training during which time active lever presses resulted in an i.v. infusion of cocaine that was paired with a light/tone cue. Next rats underwent lever extinction for 8 days followed by light/tone reactivation and a test of cue-induced cocaine-seeking behavior. Systemic injection of garcinol 30 min after reactivation significantly impaired the reconsolidation of the cocaine-associated cue memory. Further testing revealed that garcinol had no effect on drug-induced cocaine-seeking, but was capable of blocking the initial conditioned reinforcing properties of the cue and prevents the acquisition of a new response. Additional experiments showed that the effects of garcinol are specific to reactivated memories only, temporally constrained, cue-specific, long-lasting, and persist following extended cocaine access. These data provide strong evidence that the naturally occurring compound, garcinol, may be a potentially useful tool to sustain abstinence from drug abuse.

The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory

PubMed Central

Monsey, Melissa S; Sanchez, Hayde; Taylor, Jane R

2017-01-01

Sustained abstinence from cocaine use is frequently compromised by exposure to environmental stimuli that have previously been strongly associated with drug taking. Such cues trigger memories of the effects of the drug, leading to craving and potential relapse. Our work has demonstrated that manipulating cocaine-cue memories by destabilizing them through interfering with the reconsolidation process is one potential therapeutic tool by which to prolong abstinence. Here, we examine the use of the naturally occurring amnestic agent garcinol to manipulate an established cocaine-cue memory. Rats underwent 12 days of cocaine self-administration training during which time active lever presses resulted in an i.v. infusion of cocaine that was paired with a light/tone cue. Next rats underwent lever extinction for 8 days followed by light/tone reactivation and a test of cue-induced cocaine-seeking behavior. Systemic injection of garcinol 30 min after reactivation significantly impaired the reconsolidation of the cocaine-associated cue memory. Further testing revealed that garcinol had no effect on drug-induced cocaine-seeking, but was capable of blocking the initial conditioned reinforcing properties of the cue and prevents the acquisition of a new response. Additional experiments showed that the effects of garcinol are specific to reactivated memories only, temporally constrained, cue-specific, long-lasting, and persist following extended cocaine access. These data provide strong evidence that the naturally occurring compound, garcinol, may be a potentially useful tool to sustain abstinence from drug abuse. PMID:27380937

Integration of reward signalling and appetite regulating peptide systems in the control of food‐cue responses

PubMed Central

Westbrook, R F; Morris, M J

2015-01-01

Understanding the neurobiological substrates that encode learning about food‐associated cues and how those signals are modulated is of great clinical importance especially in light of the worldwide obesity problem. Inappropriate or maladaptive responses to food‐associated cues can promote over‐consumption, leading to excessive energy intake and weight gain. Chronic exposure to foods rich in fat and sugar alters the reinforcing value of foods and weakens inhibitory neural control, triggering learned, but maladaptive, associations between environmental cues and food rewards. Thus, responses to food‐associated cues can promote cravings and food‐seeking by activating mesocorticolimbic dopamine neurocircuitry, and exert physiological effects including salivation. These responses may be analogous to the cravings experienced by abstaining drug addicts that can trigger relapse into drug self‐administration. Preventing cue‐triggered eating may therefore reduce the over‐consumption seen in obesity and binge‐eating disorder. In this review we discuss recent research examining how cues associated with palatable foods can promote reward‐based feeding behaviours and the potential involvement of appetite‐regulating peptides including leptin, ghrelin, orexin and melanin concentrating hormone. These peptide signals interface with mesolimbic dopaminergic regions including the ventral tegmental area to modulate reactivity to cues associated with palatable foods. Thus, a novel target for anti‐obesity therapeutics is to reduce non‐homeostatic, reward driven eating behaviour, which can be triggered by environmental cues associated with highly palatable, fat and sugar rich foods. PMID:26403657

Accommodative and vergence responses to conflicting blur and disparity stimuli during development

PubMed Central

Bharadwaj, Shrikant R.; Candy, T. Rowan

2014-01-01

Accommodative and vergence responses of the typically developing visual system are generated using a combination of cues, including retinal blur and disparity. The developmental importance of blur and disparity cues in generating these motor responses was assessed by placing the two cues in conflict with each other. Cue-conflicts were induced by placing either −2 D lenses or 2 MA base-out prisms before both eyes of 140 subjects (2.0 months to 40.8 years) while they watched a cartoon movie binocularly at 80 cm. The frequency and amplitude of accommodation to lenses and vergence to prisms increased with age (both p < 0.001), with the vergence response (mean ± 1 SEM = 1.38 ± 0.05 MA) being slightly larger than the accommodative response (1.18 ± 0.04 D) at all ages (p = 0.007). The amplitude of these responses decreased with an increase in conflict stimuli (1 to 3 D or MA) (both p < 0.01). The coupled vergence response to −2 D lenses (0.31 ± 0.06 MA) and coupled accommodative response to 2 MA base-out prisms (0.21 ± 0.02 D) were significantly smaller than (both p < 0.001) and poorly correlated with the open-loop vergence (r = 0.12; p = 0.44) and open-loop accommodation (r = −0.08; p = 0.69), respectively. The typically developing visual system compensates for transiently induced conflicts between blur and disparity stimuli, without exhibiting a strong preference for either cue. The accuracy of this compensation decreases with an increase in amplitude of cue-conflict. PMID:20053067

Transition from lab to flight demo for model-based FLIR ATR and SAR-FLIR fusion

NASA Astrophysics Data System (ADS)

Childs, Martin B.; Carlson, Karen M.; Pujara, Neeraj

2000-08-01

Model-based automatic target recognition (ATR) using forward- looking infrared (FLIR) imagery, and using FLIR imagery combined with cues from a synthetic aperture radar (SAR) system, has been successfully demonstrated in the laboratory. For the laboratory demonstration, FLIR images, platform location, sensor data, and SAR cues were read in from files stored on computer disk. This ATR system, however, was intended to ultimately be flown in a fighter aircraft. We discuss the transition from laboratory demonstration to flight demonstration for this system. The obvious changes required were in the interfaces: the flight system must get live FLIR imagery from a sensor; it must get platform location, sensor data, and controls from the avionics computer in the aircraft via 1553 bus; and it must get SAR cues from the on-board SAR system, also via 1553 bus. Other changes included the transition to rugged hardware that would withstand the fighter aircraft environment, and the need for the system to be compact and self-contained. Unexpected as well as expected challenges were encountered. We discuss some of these challenges, how they were met, and the performance of the flight-demonstration system.

Visual Landmarks Facilitate Rodent Spatial Navigation in Virtual Reality Environments

ERIC Educational Resources Information Center

Youngstrom, Isaac A.; Strowbridge, Ben W.

2012-01-01

Because many different sensory modalities contribute to spatial learning in rodents, it has been difficult to determine whether spatial navigation can be guided solely by visual cues. Rodents moving within physical environments with visual cues engage a variety of nonvisual sensory systems that cannot be easily inhibited without lesioning brain…

Social pain and social gain in the adolescent brain: A common neural circuitry underlying both positive and negative social evaluation

PubMed Central

Dalgleish, Tim; Walsh, Nicholas D.; Mobbs, Dean; Schweizer, Susanne; van Harmelen, Anne-Laura; Dunn, Barnaby; Dunn, Valerie; Goodyer, Ian; Stretton, Jason

2017-01-01

Social interaction inherently involves the subjective evaluation of cues salient to social inclusion and exclusion. Testifying to the importance of such social cues, parts of the neural system dedicated to the detection of physical pain, the dorsal anterior cingulate cortex (dACC) and anterior insula (AI), have been shown to be equally sensitive to the detection of social pain experienced after social exclusion. However, recent work suggests that this dACC-AI matrix may index any socially pertinent information. We directly tested the hypothesis that the dACC-AI would respond to cues of both inclusion and exclusion, using a novel social feedback fMRI paradigm in a population-derived sample of adolescents. We show that the dACC and left AI are commonly activated by feedback cues of inclusion and exclusion. Our findings suggest that theoretical accounts of the dACC-AI network as a neural alarm system restricted within the social domain to the processing of signals of exclusion require significant revision. PMID:28169323

An evaluation of the HemoCue for measuring haemoglobin in field studies in Jamaica.

PubMed Central

Hudson-Thomas, M.; Bingham, K. C.; Simmons, W. K.

1994-01-01

The HemoCue system utilizes the principle of oxidation of haemoglobin to hemiglobin by sodium nitrite and the subsequent conversion of hemiglobin to hemiglobinazide by sodium azide. The reagents for these reactions are contained within a small disposable microcuvette of approximately 10 microliters in volume. A venous or capillary sample is introduced into the microcuvette by capillary action and, after reaction with the reagents, the absorbance is read in the HemoCue photometer at 565 and 880 nm. The haemoglobin concentration is then displayed as a digital reading, in either g/dl or mmol/l in 15-45 seconds. We compared haemoglobin values obtained by the HemoCue system with those from the Coulter Counter S-Plus IV in 366 pregnant women in urban Jamaica, and found a highly significant correlation (r = 0.78, P < 0.01). However, because of the convenience and ease of use of this instrument and considering the relatively high cost, we recommend it for use only as a research tool in field studies where accurate and rapid haemoglobin determinations are required. PMID:8062400

Analytical modeling and experimental validation of a magnetorheological mount

NASA Astrophysics Data System (ADS)

Nguyen, The; Ciocanel, Constantin; Elahinia, Mohammad

2009-03-01

Magnetorheological (MR) fluid has been increasingly researched and applied in vibration isolation devices. To date, the suspension system of several high performance vehicles has been equipped with MR fluid based dampers and research is ongoing to develop MR fluid based mounts for engine and powertrain isolation. MR fluid based devices have received attention due to the MR fluid's capability to change its properties in the presence of a magnetic field. This characteristic places MR mounts in the class of semiactive isolators making them a desirable substitution for the passive hydraulic mounts. In this research, an analytical model of a mixed-mode MR mount was constructed. The magnetorheological mount employs flow (valve) mode and squeeze mode. Each mode is powered by an independent electromagnet, so one mode does not affect the operation of the other. The analytical model was used to predict the performance of the MR mount with different sets of parameters. Furthermore, in order to produce the actual prototype, the analytical model was used to identify the optimal geometry of the mount. The experimental phase of this research was carried by fabricating and testing the actual MR mount. The manufactured mount was tested to evaluate the effectiveness of each mode individually and in combination. The experimental results were also used to validate the ability of the analytical model in predicting the response of the MR mount. Based on the observed response of the mount a suitable controller can be designed for it. However, the control scheme is not addressed in this study.

Evaluation of the effectiveness of elastomeric mount using vibration power flow and transmissibility methods

NASA Astrophysics Data System (ADS)

Arib Rejab, M. N.; Shukor, S. A. Abdul; Sofian, M. R. Mohd; Inayat-Hussain, J. I.; Nazirah, A.; Asyraf, I.

2017-10-01

This paper presents the results of an experimental work to determine the dynamic stiffness and loss factor of elastomeric mounts. It also presents the results of theoretical analysis to determine the transmissibility and vibration power flow of these mounts, which are associated with their contribution to structure-borne noise. Four types of elastomeric mounts were considered, where three of them were made from green natural rubber material (SMR CV60, Ekoprena and Pureprena) and one made from petroleum based synthetic rubber (EPDM). In order to determine the dynamic stiffness and loss factor of these elastomeric mounts, dynamic tests were conducted using MTS 830 Elastomer Test System. Dynamic stiffness and loss factor of these mounts were measured for a range of frequency between 5 Hz and 150 Hz, and with a dynamic amplitude of 0.2 mm (p-p). The transmissibility and vibration power flow were determined based on a simple 2-Degree-of-Freedom model representing a vibration isolation system with a flexible receiver. This model reprsents the three main parts of a vehicle, which are the powertrain and engine mounting, the flexible structure and the floor of the vehicle. The results revealed that synthetic rubber (EPDM) was only effective at high frequency region. Natural rubber (Ekoprena), on the other hand, was found to be effective at both low and high frequency regions due to its low transmissibility at resonant frequency and its ability to damp the resonance. The estimated structure-borne noise emission showed that Ekoprena has a lower contribution to structure-borne noise as compared to the other types of elastomeric mounts.

Neural Representation of Motion-In-Depth in Area MT

PubMed Central

Sanada, Takahisa M.

2014-01-01

Neural processing of 2D visual motion has been studied extensively, but relatively little is known about how visual cortical neurons represent visual motion trajectories that include a component toward or away from the observer (motion in depth). Psychophysical studies have demonstrated that humans perceive motion in depth based on both changes in binocular disparity over time (CD cue) and interocular velocity differences (IOVD cue). However, evidence for neurons that represent motion in depth has been limited, especially in primates, and it is unknown whether such neurons make use of CD or IOVD cues. We show that approximately one-half of neurons in macaque area MT are selective for the direction of motion in depth, and that this selectivity is driven primarily by IOVD cues, with a small contribution from the CD cue. Our results establish that area MT, a central hub of the primate visual motion processing system, contains a 3D representation of visual motion. PMID:25411481

Food and conspecific chemical cues modify visual behavior of zebrafish, Danio rerio.

PubMed

Stephenson, Jessica F; Partridge, Julian C; Whitlock, Kathleen E

2012-06-01

Animals use the different qualities of olfactory and visual sensory information to make decisions. Ethological and electrophysiological evidence suggests that there is cross-modal priming between these sensory systems in fish. We present the first experimental study showing that ecologically relevant chemical mixtures alter visual behavior, using adult male and female zebrafish, Danio rerio. Neutral-density filters were used to attenuate the light reaching the tank to an initial light intensity of 2.3×10(16) photons/s/m2. Fish were exposed to food cue and to alarm cue. The light intensity was then increased by the removal of one layer of filter (nominal absorbance 0.3) every minute until, after 10 minutes, the light level was 15.5×10(16) photons/s/m2. Adult male and female zebrafish responded to a moving visual stimulus at lower light levels if they had been first exposed to food cue, or to conspecific alarm cue. These results suggest the need for more integrative studies of sensory biology.

Directing driver attention with augmented reality cues

PubMed Central

Rusch, Michelle L.; Schall, Mark C.; Gavin, Patrick; Lee, John D.; Dawson, Jeffrey D.; Vecera, Shaun; Rizzo, Matthew

2013-01-01

This simulator study evaluated the effects of augmented reality (AR) cues designed to direct the attention of experienced drivers to roadside hazards. Twenty-seven healthy middle-aged licensed drivers with a range of attention capacity participated in a 54 mile (1.5 hour) drive in an interactive fixed-base driving simulator. Each participant received AR cues to potential roadside hazards in six simulated straight (9 mile long) rural roadway segments. Drivers were evaluated on response time for detecting a potentially hazardous event, detection accuracy for target (hazard) and non-target objects, and headway with respect to the hazards. Results showed no negative outcomes associated with interference. AR cues did not impair perception of non-target objects, including for drivers with lower attentional capacity. Results showed near significant response time benefits for AR cued hazards. AR cueing increased response rate for detecting pedestrians and warning signs but not vehicles. AR system false alarms and misses did not impair driver responses to potential hazards. PMID:24436635

Blockade of THC-seeking behavior and relapse in monkeys by the cannabinoid CB(1)-receptor antagonist rimonabant.

PubMed

Justinova, Zuzana; Munzar, Patrik; Panlilio, Leigh V; Yasar, Sevil; Redhi, Godfrey H; Tanda, Gianluigi; Goldberg, Steven R

2008-11-01

Accumulating evidence suggests the endocannabinoid system modulates environmental cues' ability to induce seeking of drugs, including nicotine and alcohol. However, little attention has been directed toward extending these advances to the growing problem of cannabis use disorders. Therefore, we studied intravenous self-administration of Delta(9)-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana, using a second-order schedule of drug seeking. Squirrel monkeys' lever responses produced only a brief cue light until the end of the session, when the final response delivered THC along with the cue. When a reinstatement procedure was used to model relapse following a period of abstinence, THC-seeking behavior was robustly reinstated by the cue or by pre-session administration of THC, other cannabinoid agonists, or morphine, but not cocaine. The cannabinoid antagonist rimonabant blocked cue-induced drug seeking, THC-induced drug seeking, and the direct reinforcing effects of THC. Thus, rimonabant and related medications might be effective as treatments for cannabinoid dependence.

Attenuation of saccharin-seeking in rats by orexin/hypocretin receptor 1 antagonist.

PubMed

Cason, Angie M; Aston-Jones, Gary

2013-08-01

The orexin (Orx)/hypocretin system has been implicated in reward-seeking, especially for highly salient food and drug rewards. We recently demonstrated that signaling at the OxR1 receptor is involved in sucrose reinforcement and reinstatement of sucrose-seeking elicited by sucrose-paired cues in food-restricted rats. Because sucrose reinforcement has both a hedonic and caloric component, it remains unknown what aspect of this reward drives its reinforcing value. The present study examined the involvement of the Orx system in operant responding for saccharin, a noncaloric, hedonic (sweet) reward, and in cue-induced reinstatement of extinguished saccharin-seeking in ad libitum-fed vs food-restricted male subjects. Male Sprague Dawley rats were fed ad libitum or food-restricted and trained to self-administer saccharin. We determined the effects of pretreatment with the OxR1 receptor antagonist SB-334867 (SB; 10-30 mg/kg) on fixed ratio (FR) saccharin self-administration and on cue-induced reinstatement of extinguished saccharin-seeking. SB decreased responding and number of reinforcers earned during FR responding for saccharin and decreased cue-induced reinstatement of extinguished saccharin-seeking. All of these effects were obtained similarly in food-restricted and ad libitum-fed rats. These results indicate that signaling at the OxR1 receptor is involved in saccharin reinforcement and reinstatement of saccharin-seeking elicited by saccharin-paired cues regardless of food restriction. These findings lead us to conclude that the Orx system contributes to the motivational effects of hedonic food rewards, independently of caloric value and homeostatic needs.

Framing spatial cognition: Neural representations of proximal and distal frames of reference and their roles in navigation

PubMed Central

Knierim, James J.; Hamilton, Derek A.

2011-01-01

The most common behavioral test of hippocampus-dependent, spatial learning and memory is the Morris water task, and the most commonly studied behavioral correlate of hippocampal neurons is the spatial specificity of place cells. Despite decades of intensive research, it is not completely understood how animals solve the water task and how place cells generate their spatially specific firing fields. Based on early work, it has become the accepted wisdom in the general neuroscience community that distal spatial cues are the primary sources of information used by animals to solve the water task (and similar spatial tasks) and by place cells to generate their spatial specificity. More recent research, along with earlier studies that were overshadowed by the emphasis on distal cues, put this common view into question by demonstrating primary influences of local cues and local boundaries on spatial behavior and place-cell firing. This paper first reviews the historical underpinnings of the “standard” view from a behavioral perspective, and then reviews newer results demonstrating that an animal's behavior in such spatial tasks is more strongly controlled by a local-apparatus frame of reference than by distal landmarks. The paper then reviews similar findings from the literature on the neurophysiological correlates of place cells and other spatially-correlated cells from related brain areas. A model is proposed by which distal cues primarily set the orientation of the animal's internal spatial coordinate system, via the head direction cell system, whereas local cues and apparatus boundaries primarily set the translation and scale of that coordinate system. PMID:22013211

A Microsaccadic Account of Attentional Capture and Inhibition of Return in Posner Cueing

PubMed Central

Tian, Xiaoguang; Yoshida, Masatoshi; Hafed, Ziad M.

2016-01-01

Microsaccades exhibit systematic oscillations in direction after spatial cueing, and these oscillations correlate with facilitatory and inhibitory changes in behavioral performance in the same tasks. However, independent of cueing, facilitatory and inhibitory changes in visual sensitivity also arise pre-microsaccadically. Given such pre-microsaccadic modulation, an imperative question to ask becomes: how much of task performance in spatial cueing may be attributable to these peri-movement changes in visual sensitivity? To investigate this question, we adopted a theoretical approach. We developed a minimalist model in which: (1) microsaccades are repetitively generated using a rise-to-threshold mechanism, and (2) pre-microsaccadic target onset is associated with direction-dependent modulation of visual sensitivity, as found experimentally. We asked whether such a model alone is sufficient to account for performance dynamics in spatial cueing. Our model not only explained fine-scale microsaccade frequency and direction modulations after spatial cueing, but it also generated classic facilitatory (i.e., attentional capture) and inhibitory [i.e., inhibition of return (IOR)] effects of the cue on behavioral performance. According to the model, cues reflexively reset the oculomotor system, which unmasks oscillatory processes underlying microsaccade generation; once these oscillatory processes are unmasked, “attentional capture” and “IOR” become direct outcomes of pre-microsaccadic enhancement or suppression, respectively. Interestingly, our model predicted that facilitatory and inhibitory effects on behavior should appear as a function of target onset relative to microsaccades even without prior cues. We experimentally validated this prediction for both saccadic and manual responses. We also established a potential causal mechanism for the microsaccadic oscillatory processes hypothesized by our model. We used retinal-image stabilization to experimentally control instantaneous foveal motor error during the presentation of peripheral cues, and we found that post-cue microsaccadic oscillations were severely disrupted. This suggests that microsaccades in spatial cueing tasks reflect active oculomotor correction of foveal motor error, rather than presumed oscillatory covert attentional processes. Taken together, our results demonstrate that peri-microsaccadic changes in vision can go a long way in accounting for some classic behavioral phenomena. PMID:27013991

Bio-inspired display of polarization information using selected visual cues

NASA Astrophysics Data System (ADS)

Yemelyanov, Konstantin M.; Lin, Shih-Schon; Luis, William Q.; Pugh, Edward N., Jr.; Engheta, Nader

2003-12-01

For imaging systems the polarization of electromagnetic waves carries much potentially useful information about such features of the world as the surface shape, material contents, local curvature of objects, as well as about the relative locations of the source, object and imaging system. The imaging system of the human eye however, is "polarization-blind", and cannot utilize the polarization of light without the aid of an artificial, polarization-sensitive instrument. Therefore, polarization information captured by a man-made polarimetric imaging system must be displayed to a human observer in the form of visual cues that are naturally processed by the human visual system, while essentially preserving the other important non-polarization information (such as spectral and intensity information) in an image. In other words, some forms of sensory substitution are needed for representing polarization "signals" without affecting other visual information such as color and brightness. We are investigating several bio-inspired representational methodologies for mapping polarization information into visual cues readily perceived by the human visual system, and determining which mappings are most suitable for specific applications such as object detection, navigation, sensing, scene classifications, and surface deformation. The visual cues and strategies we are exploring are the use of coherently moving dots superimposed on image to represent various range of polarization signals, overlaying textures with spatial and/or temporal signatures to segregate regions of image with differing polarization, modulating luminance and/or color contrast of scenes in terms of certain aspects of polarization values, and fusing polarization images into intensity-only images. In this talk, we will present samples of our findings in this area.

The role of orexin-A in food motivation, reward-based feeding behavior and food-induced neuronal activation in rats.

PubMed

Choi, D L; Davis, J F; Fitzgerald, M E; Benoit, S C

2010-04-28

Consumption beyond homeostatic needs, referred to here as reward-based feeding behavior, is a central contributor to the current obesity epidemic worldwide. Importantly, reward-based feeding can be driven by palatability, the taste and texture of the food, as well as cues associated with the consumption of palatable foods. The hypothalamic orexin system regulates both diet preference and anticipation of food rewards making it a likely target to modulate reward-based feeding behavior. In the current manuscript we hypothesized that orexin signaling mediates food-motivated behaviors and reward-based feeding behavior. We further hypothesized that orexin neurons and targets of the orexin system become activated in response to cues associated with the consumption of palatable food. Data from these studies suggest that orexin signaling promotes progressive ratio responding for palatable foods while blockade of orexin signaling attenuates reward-based feeding of a high fat diet. In addition, cues linked to the consumption of chocolate, or the receipt of a daily meal, activate the orexin system and its target regions differentially. Collectively, these data suggest that orexin signaling mediates reward-based feeding behavior and, within specific target regions, may regulate cue-induced overconsumption of palatable foods. Copyright 2010 IBRO. Published by Elsevier Ltd. All rights reserved.

PERIPHERAL IMMUNE SYSTEM SUPPRESSION IN EARLY ABSTINENT ALCOHOL DEPENDENT INDIVIDUALS: LINKS TO STRESS AND CUE-RELATED CRAVING

PubMed Central

Fox, Helen C; Milivojevic, Verica; Angarita, Gustavo A; Stowe, Raymond; Sinha, Rajita

2017-01-01

Background Peripheral immune system cytokines may play an integral role in underlying sensitized stress response and alcohol craving during early withdrawal. To date, the nature of these immune changes during early abstinence have not been examined. Methods Thirty-nine early abstinent, treatment-seeking alcohol dependent individuals and 46 socially drinking controls were exposed to three guided imageries: stress, alcohol cue and neutral. These were presented randomly across consecutive days. Plasma measures of tumor necrosis factor alpha (TNFα), tumor necrosis factor receptor 1 (TNFR1), interleukin-6 (IL-6), and interleukin-10 (IL-10), were collected at baseline, immediately after imagery and at various recovery time-points. Ratings of alcohol craving, negative mood and anxiety were also obtained at the same time-points. Results The alcohol group demonstrated decreased basal IL-10 compared with controls particularly following exposure to alcohol cue. They also showed a dampened TNFα and TNFR1 response to stress and cue, respectively, and a generalized suppression of IL-6. In the alcohol group, these immune system adaptations occurred alongside significant elevations in anxiety, negative mood and alcohol craving. Conclusions Findings demonstrate that broad immuno-suppression is still observed in alcohol dependent individuals after three weeks of abstinence and may be linked to motivation for alcohol. PMID:28675117

Tumor Restrictions to Oncolytic Virus

PubMed Central

Vähä-Koskela, Markus; Hinkkanen, Ari

2014-01-01

Oncolytic virotherapy has advanced since the days of its conception but therapeutic efficacy in the clinics does not seem to reach the same level as in animal models. One reason is premature oncolytic virus clearance in humans, which is a reasonable assumption considering the immune-stimulating nature of the oncolytic agents. However, several studies are beginning to reveal layers of restriction to oncolytic virotherapy that are present before an adaptive neutralizing immune response. Some of these barriers are present constitutively halting infection before it even begins, whereas others are raised by minute cues triggered by virus infection. Indeed, we and others have noticed that delivering viruses to tumors may not be the biggest obstacle to successful therapy, but instead the physical make-up of the tumor and its capacity to mount antiviral defenses seem to be the most important efficacy determinants. In this review, we summarize the constitutive and innate barriers to oncolytic virotherapy and discuss strategies to overcome them. PMID:28548066

On the Use of a Low-Cost Thermal Sensor to Improve Kinect People Detection in a Mobile Robot

PubMed Central

Susperregi, Loreto; Sierra, Basilio; Castrillón, Modesto; Lorenzo, Javier; Martínez-Otzeta, Jose María; Lazkano, Elena

2013-01-01

Detecting people is a key capability for robots that operate in populated environments. In this paper, we have adopted a hierarchical approach that combines classifiers created using supervised learning in order to identify whether a person is in the view-scope of the robot or not. Our approach makes use of vision, depth and thermal sensors mounted on top of a mobile platform. The set of sensors is set up combining the rich data source offered by a Kinect sensor, which provides vision and depth at low cost, and a thermopile array sensor. Experimental results carried out with a mobile platform in a manufacturing shop floor and in a science museum have shown that the false positive rate achieved using any single cue is drastically reduced. The performance of our algorithm improves other well-known approaches, such as C4 and histogram of oriented gradients (HOG). PMID:24172285

Beyond NK cells: the expanding universe of innate lymphoid cells.

PubMed

Cella, Marina; Miller, Hannah; Song, Christina

2014-01-01

For a long time, natural killer (NK) cells were thought to be the only innate immune lymphoid population capable of responding to invading pathogens under the influence of changing environmental cues. In the last few years, an increasing amount of evidence has shown that a number of different innate lymphoid cell (ILC) populations found at mucosal sites rapidly respond to locally produced cytokines in order to establish or maintain homeostasis. These ILC populations closely mirror the phenotype of adaptive T helper subsets in their repertoire of secreted soluble factors. Early in the immune response, ILCs are responsible for setting the stage to mount an adaptive T cell response that is appropriate for the incoming insult. Here, we review the diversity of ILC subsets and discuss similarities and differences between ILCs and NK cells in function and key transcriptional factors required for their development.

Approximation of Engine Casing Temperature Constraints for Casing Mounted Electronics

NASA Technical Reports Server (NTRS)

Kratz, Jonathan L.; Culley, Dennis E.; Chapman, Jeffryes W.

2017-01-01

The performance of propulsion engine systems is sensitive to weight and volume considerations. This can severely constrain the configuration and complexity of the control system hardware. Distributed Engine Control technology is a response to these concerns by providing more flexibility in designing the control system, and by extension, more functionality leading to higher performing engine systems. Consequently, there can be a weight benefit to mounting modular electronic hardware on the engine core casing in a high temperature environment. This paper attempts to quantify the in-flight temperature constraints for engine casing mounted electronics. In addition, an attempt is made at studying heat soak back effects. The Commercial Modular Aero Propulsion System Simulation 40k (C-MAPSS40k) software is leveraged with real flight data as the inputs to the simulation. A two-dimensional (2-D) heat transfer model is integrated with the engine simulation to approximate the temperature along the length of the engine casing. This modification to the existing C-MAPSS40k software will provide tools and methodologies to develop a better understanding of the requirements for the embedded electronics hardware in future engine systems. Results of the simulations are presented and their implications on temperature constraints for engine casing mounted electronics is discussed.

Approximation of Engine Casing Temperature Constraints for Casing Mounted Electronics

NASA Technical Reports Server (NTRS)

Kratz, Jonathan; Culley, Dennis; Chapman, Jeffryes

2016-01-01

The performance of propulsion engine systems is sensitive to weight and volume considerations. This can severely constrain the configuration and complexity of the control system hardware. Distributed Engine Control technology is a response to these concerns by providing more flexibility in designing the control system, and by extension, more functionality leading to higher performing engine systems. Consequently, there can be a weight benefit to mounting modular electronic hardware on the engine core casing in a high temperature environment. This paper attempts to quantify the in-flight temperature constraints for engine casing mounted electronics. In addition, an attempt is made at studying heat soak back effects. The Commercial Modular Aero Propulsion System Simulation 40k (C-MAPSS40k) software is leveraged with real flight data as the inputs to the simulation. A two-dimensional (2-D) heat transfer model is integrated with the engine simulation to approximate the temperature along the length of the engine casing. This modification to the existing C-MAPSS40k software will provide tools and methodologies to develop a better understanding of the requirements for the embedded electronics hardware in future engine systems. Results of the simulations are presented and their implications on temperature constraints for engine casing mounted electronics is discussed.

Parallel pathways for cross-modal memory retrieval in Drosophila.

PubMed

Zhang, Xiaonan; Ren, Qingzhong; Guo, Aike

2013-05-15

Memory-retrieval processing of cross-modal sensory preconditioning is vital for understanding the plasticity underlying the interactions between modalities. As part of the sensory preconditioning paradigm, it has been hypothesized that the conditioned response to an unreinforced cue depends on the memory of the reinforced cue via a sensory link between the two cues. To test this hypothesis, we studied cross-modal memory-retrieval processing in a genetically tractable model organism, Drosophila melanogaster. By expressing the dominant temperature-sensitive shibire(ts1) (shi(ts1)) transgene, which blocks synaptic vesicle recycling of specific neural subsets with the Gal4/UAS system at the restrictive temperature, we specifically blocked visual and olfactory memory retrieval, either alone or in combination; memory acquisition remained intact for these modalities. Blocking the memory retrieval of the reinforced olfactory cues did not impair the conditioned response to the unreinforced visual cues or vice versa, in contrast to the canonical memory-retrieval processing of sensory preconditioning. In addition, these conditioned responses can be abolished by blocking the memory retrieval of the two modalities simultaneously. In sum, our results indicated that a conditioned response to an unreinforced cue in cross-modal sensory preconditioning can be recalled through parallel pathways.

77 FR 38777 - 36(b)(1) Arms Sales Notification

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... Systems (SINCGARS), 200 M2 Chrysler Mount Machine Guns, 400 7.62MM M240 Machine Guns, 12,049,842... Exportable Single Channel Ground and Airborne Radio Systems (SINCGARS), 200 M2 Chrysler Mount Machine Guns, and 400 7.62MM M240 Machine Guns. The possible sale also includes 12,049,842 Ammunition Rounds...

The port side view of the Orbiter Discovery while mounted ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

The port side view of the Orbiter Discovery while mounted atop the 76-wheeled orbiter transfer system as it is being rolled from the Orbiter Processing Facility to the Vehicle Assembly Building at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

The starboard side view of the Orbiter Discovery while mounted ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

The starboard side view of the Orbiter Discovery while mounted atop the 76-wheeled orbiter transfer system as it is being rolled from the Orbiter Processing Facility to the Vehicle Assembly Building at Kennedy Space Center. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

Hitchhiker capabilities

NASA Technical Reports Server (NTRS)

Goldsmith, Theodore C.

1988-01-01

A carrier system has been developed for economical and quick response flight of small attached payloads on the space shuttle. Hitchhiker can accommodate up to 750 lb of customer payloads in canisters or mounted to an exposed side-mount plate, or up to 1200 lb mounted on a cross-bay structure. The carrier connects to the orbiter's electrical systems and provides up to six customers with standard electrical services including power, real time telemetry and commands. A transparent data and command system concept is employed to allow the customer to easily use his own ground support equipment and personnel to control his payload during integration and flight operations. A general description of the Hitchhiker program and the Shuttle Payload of Opportunity Carrier (SPOC) is given and future enhancements are outlined.

Prior Haloperidol, but not Olanzapine, Exposure Augments the Pursuit of Reward Cues: Implications for Substance Abuse in Schizophrenia

PubMed Central

Samaha, Anne-Noël

2013-01-01

Drug abuse and addiction are excessively common in schizophrenia. Chronic antipsychotic treatment might contribute to this comorbidity by inducing supersensitivity within the brain’s dopamine system. Dopamine supersensitivity can enhance the incentive motivational properties of reward cues, and reward cues contribute to the maintenance and severity of drug addiction. We have shown previously that rats withdrawn from continuous haloperidol (HAL) treatment (via subcutaneous minipump) develop dopamine supersensitivity and pursue reward cues more vigorously than HAL-naive rats following an amphetamine (AMPH) challenge. Atypical antipsychotic drugs are thought to be less likely than typicals to produce dopamine supersensitivity. Thus, we compared the effects of HAL and the atypical antipsychotic olanzapine (OLZ) on the pursuit of reward cues. Rats were trained to associate a light-tone cue with water then treated with HAL or OLZ. Following antipsychotic withdrawal, we assessed AMPH-induced enhancement of lever pressing for the cue. Withdrawal from HAL, but not from OLZ, enhanced this effect. HAL, but not OLZ, also enhanced AMPH-induced psychomotor activation and c-fos mRNA expression in the caudate-putamen. Thus, prior HAL, but not OLZ, enhanced conditioned reward following an AMPH challenge, and this was potentially linked to enhanced behavioral sensitivity to AMPH and AMPH-induced engagement of the caudate-putamen. These findings suggest that HAL, but not an atypical like OLZ, modifies reward circuitry in ways that increase responsiveness to reward cues. Because enhanced responsiveness to reward cues can promote drug-seeking behavior, it should be investigated whether atypical antipsychotics might be a preferential option in schizophrenic patients at risk for drug abuse or addiction. PMID:22927669

Glycogen synthase kinase 3β in the basolateral amygdala is critical for the reconsolidation of cocaine reward memory.

PubMed

Wu, Ping; Xue, Yan-Xue; Ding, Zeng-Bo; Xue, Li-Fen; Xu, Chun-Mei; Lu, Lin

2011-07-01

Exposure to cocaine-associated conditioned stimuli elicits craving and increases the probability of cocaine relapse in cocaine users even after extended periods of abstinence. Recent evidence indicates that cocaine seeking can be inhibited by disrupting the reconsolidation of the cocaine cue memories and that basolateral amygdala (BLA) neuronal activity plays a role in this effect. Previous studies demonstrated that glycogen synthase kinase 3β (GSK-3β) plays a role in the reconsolidation of fear memory. Here, we used a conditioned place preference procedure to examine the role of GSK-3β in the BLA in the reconsolidation of cocaine cue memories. GSK-3β activity in the BLA, but not central amygdala (CeA), in rats that acquired cocaine (10 mg/kg)-induced conditioned place preference increased after re-exposure to a previously cocaine-paired chamber (i.e., a memory reactivation procedure). Systemic injections of the GSK-3β inhibitor lithium chloride after memory reactivation impaired the reconsolidation of cocaine cue memories and inhibited subsequent cue-induced GSK-3β activity in the BLA. Basolateral amygdala, but not central amygdala, injections of SB216763, a selective inhibitor of GSK-3β, immediately after the reactivation of cocaine cue memories also disrupted cocaine cue memory reconsolidation and prevented cue-induced increases in GSK-3β activity in the BLA. The effect of SB216763 on the reconsolidation of cocaine cue memories lasted at least 2 weeks and was not recovered by a cocaine priming injection. These results indicate that GSK-3β activity in the BLA mediates the reconsolidation of cocaine cue memories. © 2011 The Authors. Journal of Neurochemistry © 2011 International Society for Neurochemistry.

Chemical and visual communication during mate searching in rock shrimp.

PubMed

Díaz, Eliecer R; Thiel, Martin

2004-06-01

Mate searching in crustaceans depends on different communicational cues, of which chemical and visual cues are most important. Herein we examined the role of chemical and visual communication during mate searching and assessment in the rock shrimp Rhynchocinetes typus. Adult male rock shrimp experience major ontogenetic changes. The terminal molt stages (named "robustus") are dominant and capable of monopolizing females during the mating process. Previous studies had shown that most females preferably mate with robustus males, but how these dominant males and receptive females find each other is uncertain, and is the question we examined herein. In a Y-maze designed to test for the importance of waterborne chemical cues, we observed that females approached the robustus male significantly more often than the typus male. Robustus males, however, were unable to locate receptive females via chemical signals. Using an experimental set-up that allowed testing for the importance of visual cues, we demonstrated that receptive females do not use visual cues to select robustus males, but robustus males use visual cues to find receptive females. Visual cues used by the robustus males were the tumults created by agitated aggregations of subordinate typus males around the receptive females. These results indicate a strong link between sexual communication and the mating system of rock shrimp in which dominant males monopolize receptive females. We found that females and males use different (sex-specific) communicational cues during mate searching and assessment, and that the sexual communication of rock shrimp is similar to that of the American lobster, where females are first attracted to the dominant males by chemical cues emitted by these males. A brief comparison between these two species shows that female behaviors during sexual communication contribute strongly to the outcome of mate searching and assessment.

Aeroservoelastic Testing of a Sidewall Mounted Free Flying Wind-Tunnel Model

NASA Technical Reports Server (NTRS)

Scott, Robert C.; Vetter, Travis K.; Penning, Kevin B.; Coulson, David A.; Heeg, Jennifer

2008-01-01

A team comprised of the Air Force Research Laboratory (AFRL), Northrop Grumman, Lockheed Martin, and the NASA Langley Research Center conducted three j wind-tunnel tests in the Transonic Dynamics Tunnel to demonstrate active control technologies relevant to large, exible vehicles. In the rst of these three tests, a semispan, aeroelastically scaled, wind-tunnel model of a ying wing SensorCraft vehi- cle was mounted to a force balance to demonstrate gust load alleviation. In the second and third tests, the same wing was mated to a new, multi-degree-of-freedom, sidewall mount. This mount allowed the half-span model to translate vertically and pitch at the wing root, allowing better simulation of the full span vehicle's rigid-body modes. Gust Load Alleviation (GLA) and Body Freedom Flutter (BFF) suppression were successfully demonstrated. The rigid body degrees-of-freedom required that the model be own in the wind tunnel using an active control system. This risky mode of testing necessitated that a model arrestment system be integrated into the new mount. The safe and successful completion of these free-flying tests required the development and integration of custom hardware and software. This paper describes the many systems, software, and procedures that were developed as part of this effort.

Biologically-inspired robust and adaptive multi-sensor fusion and active control

NASA Astrophysics Data System (ADS)

Khosla, Deepak; Dow, Paul A.; Huber, David J.

2009-04-01

In this paper, we describe a method and system for robust and efficient goal-oriented active control of a machine (e.g., robot) based on processing, hierarchical spatial understanding, representation and memory of multimodal sensory inputs. This work assumes that a high-level plan or goal is known a priori or is provided by an operator interface, which translates into an overall perceptual processing strategy for the machine. Its analogy to the human brain is the download of plans and decisions from the pre-frontal cortex into various perceptual working memories as a perceptual plan that then guides the sensory data collection and processing. For example, a goal might be to look for specific colored objects in a scene while also looking for specific sound sources. This paper combines three key ideas and methods into a single closed-loop active control system. (1) Use high-level plan or goal to determine and prioritize spatial locations or waypoints (targets) in multimodal sensory space; (2) collect/store information about these spatial locations at the appropriate hierarchy and representation in a spatial working memory. This includes invariant learning of these spatial representations and how to convert between them; and (3) execute actions based on ordered retrieval of these spatial locations from hierarchical spatial working memory and using the "right" level of representation that can efficiently translate into motor actions. In its most specific form, the active control is described for a vision system (such as a pantilt- zoom camera system mounted on a robotic head and neck unit) which finds and then fixates on high saliency visual objects. We also describe the approach where the goal is to turn towards and sequentially foveate on salient multimodal cues that include both visual and auditory inputs.

Facilitating Children’s Ability to Distinguish Symbols for Emotions: The Effects of Background Color Cues and Spatial Arrangement of Symbols on Accuracy and Speed of Search

PubMed Central

Wilkinson, Krista M.; Snell, Julie

2012-01-01

Purpose Communication about feelings is a core element of human interaction. Aided augmentative and alternative communication systems must therefore include symbols representing these concepts. The symbols must be readily distinguishable in order for users to communicate effectively. However, emotions are represented within most systems by schematic faces in which subtle distinctions are difficult to represent. We examined whether background color cuing and spatial arrangement might help children identify symbols for different emotions. Methods Thirty nondisabled children searched for symbols representing emotions within an 8-choice array. On some trials, a color cue signaled the valence of the emotion (positive vs. negative). Additionally, symbols were either organized with the negatively-valenced symbols at the top and the positive symbols on the bottom of the display, or the symbols were distributed randomly throughout. Dependent variables were accuracy and speed of responses. Results The speed with which children could locate a target was significantly faster for displays in which symbols were clustered by valence, but only when the symbols had white backgrounds. Addition of a background color cue did not facilitate responses. Conclusions Rapid search was facilitated by a spatial organization cue, but not by the addition of background color. Further examination of the situations in which color cues may be useful is warranted. PMID:21813821

Facilitating children's ability to distinguish symbols for emotions: the effects of background color cues and spatial arrangement of symbols on accuracy and speed of search.

PubMed

Wilkinson, Krista M; Snell, Julie

2011-11-01

Communication about feelings is a core element of human interaction. Aided augmentative and alternative communication systems must therefore include symbols representing these concepts. The symbols must be readily distinguishable in order for users to communicate effectively. However, emotions are represented within most systems by schematic faces in which subtle distinctions are difficult to represent. We examined whether background color cuing and spatial arrangement might help children identify symbols for different emotions. Thirty nondisabled children searched for symbols representing emotions within an 8-choice array. On some trials, a color cue signaled the valence of the emotion (positive vs. negative). Additionally, the symbols were either (a) organized with the negatively valenced symbols at the top and the positive symbols on the bottom of the display or (b) distributed randomly throughout. Dependent variables were accuracy and speed of responses. The speed with which children could locate a target was significantly faster for displays in which symbols were clustered by valence, but only when the symbols had white backgrounds. Addition of a background color cue did not facilitate responses. Rapid search was facilitated by a spatial organization cue, but not by the addition of background color. Further examination of the situations in which color cues may be useful is warranted.

Mechanical control of tissue-engineered bone.

PubMed

Hung, Ben P; Hutton, Daphne L; Grayson, Warren L

2013-01-31

Bone is a load-bearing tissue and physical forces play key roles in the development and maintenance of its structure. Mechanical cues can stimulate the expression of an osteogenic phenotype, enhance matrix and mineral deposition, and influence tissue organization to improve the functional outcome of engineered bone grafts. In recent years, a number of studies have investigated the effects of biophysical forces on the bone formation properties of osteoprogenitor cells. The application of physiologically relevant stimuli to tissue-engineered bone may be determined through observation and understanding of forces to which osteoblasts, osteoclasts, and osteocytes are exposed in native bone. Subsequently, these cues may be parameterized and their effects studied in well-defined in vitro systems. The osteo-inductive effects of three specific mechanical cues - shear stress, substrate rigidity, and nanotopography - on cells cultured in monolayer or in three-dimensional biomaterial scaffolds in vitro are reviewed. Additionally, we address the time-dependent effects of mechanical cues on vascular infiltration and de novo bone formation in acellular scaffolds implanted into load-bearing sites in vivo. Recent studies employing cutting-edge advances in biomaterial fabrication and bioreactor design have provided key insights into the role of mechanical cues on cellular fate and tissue properties of engineered bone grafts. By providing mechanistic understanding, future studies may go beyond empirical approaches to rational design of engineering systems to control tissue development.

Characterization of Multilayer Piezoelectric Actuators for Use in Active Isolation Mounts

NASA Technical Reports Server (NTRS)

Wise, Stephanie A.; Hooker, Matthew W.

1997-01-01

Active mounts are desirable for isolating spacecraft science instruments from on-board vibrational sources such as motors and release mechanisms. Such active isolation mounts typically employ multilayer piezoelectric actuators to cancel these vibrational disturbances. The actuators selected for spacecraft systems must consume minimal power while exhibiting displacements of 5 to 10 micron under load. This report describes a study that compares the power consumption, displacement, and load characteristics of four commercially available multilayer piezoelectric actuators. The results of this study indicate that commercially available actuators exist that meet or exceed the design requirements used in spacecraft isolation mounts.

Multi-Mounted X-Ray Computed Tomography.

PubMed

Fu, Jian; Liu, Zhenzhong; Wang, Jingzheng

2016-01-01

Most existing X-ray computed tomography (CT) techniques work in single-mounted mode and need to scan the inspected objects one by one. It is time-consuming and not acceptable for the inspection in a large scale. In this paper, we report a multi-mounted CT method and its first engineering implementation. It consists of a multi-mounted scanning geometry and the corresponding algebraic iterative reconstruction algorithm. This approach permits the CT rotation scanning of multiple objects simultaneously without the increase of penetration thickness and the signal crosstalk. Compared with the conventional single-mounted methods, it has the potential to improve the imaging efficiency and suppress the artifacts from the beam hardening and the scatter. This work comprises a numerical study of the method and its experimental verification using a dataset measured with a developed multi-mounted X-ray CT prototype system. We believe that this technique is of particular interest for pushing the engineering applications of X-ray CT.

The Impact of Rechargeable Batteries: Quantifying the Cost and Weight for a Marine Infantry Battalion

DTIC Science & Technology

2011-12-01

Suitcase Portable Charger (SPC), Vehicle - Mounted Charger (VMC), Solar Portable Power System (SPACES) 15. NUMBER OF PAGES 77 16. PRICE CODE 17...battery (MCCOC, 2010): the Soldier Portable Charger (SPC), the Vehicle Mounted Charger (VMC), and the Solar Portable Alternative Communication Energy...Suitcase Portable Charger TO&E Table of Organization and Equipment UHF Ultra High Frequency VHF Very High Frequency VMC Vehicle Mounted

The habenula governs the attribution of incentive salience to reward predictive cues

PubMed Central

Danna, Carey L.; Shepard, Paul D.; Elmer, Greg I.

2013-01-01

The attribution of incentive salience to reward associated cues is critical for motivation and the pursuit of rewards. Disruptions in the integrity of the neural systems controlling these processes can lead to avolition and anhedonia, symptoms that cross the diagnostic boundaries of many neuropsychiatric illnesses. Here, we consider whether the habenula (Hb), a region recently demonstrated to encode negatively valenced events, also modulates the attribution of incentive salience to a neutral cue predicting a food reward. The Pavlovian autoshaping paradigm was used in the rat as an investigative tool to dissociate Pavlovian learning processes imparting strictly predictive value from learning that attributes incentive motivational value. Electrolytic lesions of the fasciculus retroflexus (fr), the sole pathway through which descending Hb efferents are conveyed, significantly increased incentive salience as measured by conditioned approaches to a cue light predictive of reward. Conversely, generation of a fictive Hb signal via fr stimulation during CS+ presentation significantly decreased the incentive salience of the predictive cue. Neither manipulation altered the reward predictive value of the cue as measured by conditioned approach to the food. Our results provide new evidence supporting a significant role for the Hb in governing the attribution of incentive motivational salience to reward predictive cues and further imply that pathological changes in Hb activity could contribute to the aberrant pursuit of debilitating goals or avolition and depression-like symptoms. PMID:24368898

The Effects of Age and Preoral Sensorimotor Cues on Anticipatory Mouth Movement During Swallowing

PubMed Central

Moon, Jerald B.; Goodman, Shawn S.

2016-01-01

Purpose The aim of this study was to investigate the effects of preoral sensorimotor cues on anticipatory swallowing/eating-related mouth movements in older and younger adults. It was hypothesized that these cues are essential to timing anticipatory oral motor patterns, and these movements are delayed in older as compared with younger adults. Method Using a 2 × 2 repeated-measures design, eating-related lip, jaw, and hand movements were recorded from 24 healthy older (ages 70–85 years) and 24 healthy younger (ages 18–30 years) adults under 4 conditions: typical self-feeding, typical assisted feeding (proprioceptive loss), sensory-loss self-feeding (auditory and visual loss/degradation), and sensory-loss assisted feeding (loss/degradation of all cues). Results All participants demonstrated anticipatory mouth opening. The absence of proprioception delayed lip-lowering onset, and sensory loss more negatively affected offset. Given at least 1 preoral sensorimotor cue, older adults initiated movement earlier than younger adults. Conclusions Preoral sensorimotor information influences anticipatory swallowing/eating-related mouth movements, highlighting the importance of these cues. Earlier movement in older adults may be a compensation, facilitating safe swallowing given other age-related declines. Further research is needed to determine if the negative impact of cue removal may be further exacerbated in a nonhealthy system (e.g., presence of dysphagia or disease), potentially increasing swallowing- and eating-related risks. PMID:26540553

Passive exposure to electronic cigarette (e-cigarette) use increases desire for combustible and e-cigarettes in young adult smokers

PubMed Central

King, Andrea C; Smith, Lia J; McNamara, Patrick J; Matthews, Alicia K; Fridberg, Daniel J

2016-01-01

Background Passive exposure to combustible cigarette use has been shown to act as a cue to increase smoking urge. Given the resemblance of e-cigarettes and other electronic nicotine delivery systems (ENDS) to combustible cigarettes, we examined whether these devices could also act as a cue to increase smoking desire and urges in those passively exposed. Methods Young adult daily smokers (age 18–35 years; N=60) completed subjective ratings before and after exposure to a study confederate drinking bottled water (control cue) and then smoking either a combustible or e-cigarette (active cue). Smoking desire and urge ratings were measured with visual analogue scale items for desire for a regular and an e-cigarette and the Brief Questionnaire of Smoking Urges. Results Passive exposure to both the e-cigarette and combustible cigarette cue significantly increased observers’ ratings of desire and urge to smoke a regular cigarette (all ps<0.05). Exposure to the e-cigarette cue but not the regular cigarette cue also increased desire to smoke an e-cigarette (p<0.01). Conclusions The results provide the first evidence in a controlled setting that electronic cigarette exposure may evoke smoking urges in young adult daily smokers. With replication, these findings may have relevance for ENDS regulation and policy. PMID:24848637

Cue-exposure therapy to decrease alcohol craving in virtual environment.

PubMed

Lee, Jang-Han; Kwon, Hyoseok; Choi, Joonho; Yang, Byung-Hwan

2007-10-01

During abstinence from alcohol, craving is elicited by the cues and contexts previously associated with alcohol, which contribute to relapse. To prevent the craving and relapse experienced by alcoholics, cue-exposure therapy (CET) has been used to extinguish the association between alcohol and alcohol-related cues and contexts. This study applied CET, using a virtual reality (VR) system, to eight members of an Alcoholics Anonymous group for eight sessions. Cues and contexts most likely to elicit an urge to drink were selected through a preliminary survey in order to compose VR-CET scenarios: a glass, a bottle, food, and a bar were judged to be the most tempting for people in alcohol dependence and abstinence. Using these cues and contexts, a Japanese-style pub and a western bar were created. Each session was administered for 30 minutes by a psychiatrist and included an introduction, immersion, VR navigation, interviews about feelings, and self-report questionnaires about cravings. The eight sessions consisted of initial and closing sessions and person-, object-, and situation-focused sessions. As a result, a reduction in cue-elicited craving after VR-CET was reported. A mean score of 15.75 (SD = 10.91) on the Alcohol Urge Questionnaire in the first session decreased to 11.50 (SD = 5.76) in the final session. This study suggests that using virtual reality can enhance the effectiveness of CET.

Nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress?

PubMed

Peciña, Susana; Schulkin, Jay; Berridge, Kent C

2006-04-13

Corticotropin-releasing factor (CRF) is typically considered to mediate aversive aspects of stress, fear and anxiety. However, CRF release in the brain is also elicited by natural rewards and incentive cues, raising the possibility that some CRF systems in the brain mediate an independent function of positive incentive motivation, such as amplifying incentive salience. Here we asked whether activation of a limbic CRF subsystem magnifies the increase in positive motivation for reward elicited by incentive cues previously associated with that reward, in a way that might exacerbate cue-triggered binge pursuit of food or other incentives? We assessed the impact of CRF microinjections into the medial shell of nucleus accumbens using a pure incentive version of Pavlovian-Instrumental transfer, a measure specifically sensitive to the incentive salience of reward cues (which it separates from influences of aversive stress, stress reduction, frustration and other traditional explanations for stress-increased behavior). Rats were first trained to press one of two levers to obtain sucrose pellets, and then separately conditioned to associate a Pavlovian cue with free sucrose pellets. On test days, rats received microinjections of vehicle, CRF (250 or 500 ng/0.2 microl) or amphetamine (20 microg/0.2 microl). Lever pressing was assessed in the presence or absence of the Pavlovian cues during a half-hour test. Microinjections of the highest dose of CRF (500 ng) or amphetamine (20 microg) selectively enhanced the ability of Pavlovian reward cues to trigger phasic peaks of increased instrumental performance for a sucrose reward, each peak lasting a minute or so before decaying after the cue. Lever pressing was not enhanced by CRF microinjections in the baseline absence of the Pavlovian cue or during the presentation without a cue, showing that the CRF enhancement could not be explained as a result of generalized motor arousal, frustration or stress, or by persistent attempts to ameliorate aversive states. We conclude that CRF in nucleus accumbens shell amplifies positive motivation for cued rewards, in particular by magnifying incentive salience that is attributed to Pavlovian cues previously associated with those rewards. CRF-induced magnification of incentive salience provides a novel explanation as to why stress may produce cue-triggered bursts of binge eating, drug addiction relapse, or other excessive pursuits of rewards.

Nucleus accumbens corticotropin-releasing factor increases cue-triggered motivation for sucrose reward: paradoxical positive incentive effects in stress?

PubMed Central

Peciña, Susana; Schulkin, Jay; Berridge, Kent C

2006-01-01

Background Corticotropin-releasing factor (CRF) is typically considered to mediate aversive aspects of stress, fear and anxiety. However, CRF release in the brain is also elicited by natural rewards and incentive cues, raising the possibility that some CRF systems in the brain mediate an independent function of positive incentive motivation, such as amplifying incentive salience. Here we asked whether activation of a limbic CRF subsystem magnifies the increase in positive motivation for reward elicited by incentive cues previously associated with that reward, in a way that might exacerbate cue-triggered binge pursuit of food or other incentives? We assessed the impact of CRF microinjections into the medial shell of nucleus accumbens using a pure incentive version of Pavlovian-Instrumental transfer, a measure specifically sensitive to the incentive salience of reward cues (which it separates from influences of aversive stress, stress reduction, frustration and other traditional explanations for stress-increased behavior). Rats were first trained to press one of two levers to obtain sucrose pellets, and then separately conditioned to associate a Pavlovian cue with free sucrose pellets. On test days, rats received microinjections of vehicle, CRF (250 or 500 ng/0.2 μl) or amphetamine (20 μg/0.2 μl). Lever pressing was assessed in the presence or absence of the Pavlovian cues during a half-hour test. Results Microinjections of the highest dose of CRF (500 ng) or amphetamine (20 μg) selectively enhanced the ability of Pavlovian reward cues to trigger phasic peaks of increased instrumental performance for a sucrose reward, each peak lasting a minute or so before decaying after the cue. Lever pressing was not enhanced by CRF microinjections in the baseline absence of the Pavlovian cue or during the presentation without a cue, showing that the CRF enhancement could not be explained as a result of generalized motor arousal, frustration or stress, or by persistent attempts to ameliorate aversive states. Conclusion We conclude that CRF in nucleus accumbens shell amplifies positive motivation for cued rewards, in particular by magnifying incentive salience that is attributed to Pavlovian cues previously associated with those rewards. CRF-induced magnification of incentive salience provides a novel explanation as to why stress may produce cue-triggered bursts of binge eating, drug addiction relapse, or other excessive pursuits of rewards. PMID:16613600

Driver Distraction Using Visual-Based Sensors and Algorithms.

PubMed

Fernández, Alberto; Usamentiaga, Rubén; Carús, Juan Luis; Casado, Rubén

2016-10-28

Driver distraction, defined as the diversion of attention away from activities critical for safe driving toward a competing activity, is increasingly recognized as a significant source of injuries and fatalities on the roadway. Additionally, the trend towards increasing the use of in-vehicle information systems is critical because they induce visual, biomechanical and cognitive distraction and may affect driving performance in qualitatively different ways. Non-intrusive methods are strongly preferred for monitoring distraction, and vision-based systems have appeared to be attractive for both drivers and researchers. Biomechanical, visual and cognitive distractions are the most commonly detected types in video-based algorithms. Many distraction detection systems only use a single visual cue and therefore, they may be easily disturbed when occlusion or illumination changes appear. Moreover, the combination of these visual cues is a key and challenging aspect in the development of robust distraction detection systems. These visual cues can be extracted mainly by using face monitoring systems but they should be completed with more visual cues (e.g., hands or body information) or even, distraction detection from specific actions (e.g., phone usage). Additionally, these algorithms should be included in an embedded device or system inside a car. This is not a trivial task and several requirements must be taken into account: reliability, real-time performance, low cost, small size, low power consumption, flexibility and short time-to-market. The key points for the development and implementation of sensors to carry out the detection of distraction will also be reviewed. This paper shows a review of the role of computer vision technology applied to the development of monitoring systems to detect distraction. Some key points considered as both future work and challenges ahead yet to be solved will also be addressed.

Driver Distraction Using Visual-Based Sensors and Algorithms

PubMed Central

Fernández, Alberto; Usamentiaga, Rubén; Carús, Juan Luis; Casado, Rubén

2016-01-01

Driver distraction, defined as the diversion of attention away from activities critical for safe driving toward a competing activity, is increasingly recognized as a significant source of injuries and fatalities on the roadway. Additionally, the trend towards increasing the use of in-vehicle information systems is critical because they induce visual, biomechanical and cognitive distraction and may affect driving performance in qualitatively different ways. Non-intrusive methods are strongly preferred for monitoring distraction, and vision-based systems have appeared to be attractive for both drivers and researchers. Biomechanical, visual and cognitive distractions are the most commonly detected types in video-based algorithms. Many distraction detection systems only use a single visual cue and therefore, they may be easily disturbed when occlusion or illumination changes appear. Moreover, the combination of these visual cues is a key and challenging aspect in the development of robust distraction detection systems. These visual cues can be extracted mainly by using face monitoring systems but they should be completed with more visual cues (e.g., hands or body information) or even, distraction detection from specific actions (e.g., phone usage). Additionally, these algorithms should be included in an embedded device or system inside a car. This is not a trivial task and several requirements must be taken into account: reliability, real-time performance, low cost, small size, low power consumption, flexibility and short time-to-market. The key points for the development and implementation of sensors to carry out the detection of distraction will also be reviewed. This paper shows a review of the role of computer vision technology applied to the development of monitoring systems to detect distraction. Some key points considered as both future work and challenges ahead yet to be solved will also be addressed. PMID:27801822

Conceptual design study: Cold water pipe systems for self-mounted OTEC powerplants

NASA Astrophysics Data System (ADS)

1981-02-01

The conceptual design and installation aspects of cold water pipes (CWP) systems for shelf mounted OTEC power plants in Puerto Rico and Hawaii are considered. The CWP systems using Fiberglass Reinforced Plastic (FRP) and steel were designed; the FRP, can be controlled by varying the core thickness; and steel is used as a structural material in offshore applications. A marine railway approach was chosen for installation of the CWP. Two methods for pulling the track for the railway down the pipe fairway to its final location are presented. The track is permanently fastened to the sloping seabed with piles installed by a remotely controlled cart that rides on the track itself. Both the marine railway and the shelf mounted platform that houses the OTEC power plant require an anodic or equivalent corrosion protection system.

Color Helmet Mounted Display System with Real Time Computer Generated and Video Imagery for In-Flight Simulation

NASA Technical Reports Server (NTRS)

Sawyer, Kevin; Jacobsen, Robert; Aiken, Edwin W. (Technical Monitor)

1995-01-01

NASA Ames Research Center and the US Army are developing the Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL) using a Sikorsky UH-60 helicopter for the purpose of flight systems research. A primary use of the RASCAL is in-flight simulation for which the visual scene will use computer generated imagery and synthetic vision. This research is made possible in part to a full color wide field of view Helmet Mounted Display (HMD) system that provides high performance color imagery suitable for daytime operations in a flight-rated package. This paper describes the design and performance characteristics of the HMD system. Emphasis is placed on the design specifications, testing, and integration into the aircraft of Kaiser Electronics' RASCAL HMD system that was designed and built under contract for NASA. The optical performance and design of the Helmet mounted display unit will be discussed as well as the unique capabilities provided by the system's Programmable Display Generator (PDG).

System and method for reproducibly mounting an optical element

DOEpatents

Eisenbies, Stephen; Haney, Steven

2005-05-31

The present invention provides a two-piece apparatus for holding and aligning the MEMS deformable mirror. The two-piece apparatus comprises a holding plate for fixedly holding an adaptive optics element in an overall optical system and a base spatially fixed with respect to the optical system and adapted for mounting and containing the holding plate. The invention further relates to a means for configuring the holding plate through adjustments to each of a number of off-set pads touching each of three orthogonal plane surfaces on the base, wherein through the adjustments the orientation of the holding plate, and the adaptive optics element attached thereto, can be aligned with respect to the optical system with six degrees of freedom when aligning the plane surface of the optical element. The mounting system thus described also enables an operator to repeatedly remove and restore the adaptive element in the optical system without the need to realign the system once that element has been aligned.

Bayesian integration of position and orientation cues in perception of biological and non-biological forms.

PubMed

Thurman, Steven M; Lu, Hongjing

2014-01-01

Visual form analysis is fundamental to shape perception and likely plays a central role in perception of more complex dynamic shapes, such as moving objects or biological motion. Two primary form-based cues serve to represent the overall shape of an object: the spatial position and the orientation of locations along the boundary of the object. However, it is unclear how the visual system integrates these two sources of information in dynamic form analysis, and in particular how the brain resolves ambiguities due to sensory uncertainty and/or cue conflict. In the current study, we created animations of sparsely-sampled dynamic objects (human walkers or rotating squares) comprised of oriented Gabor patches in which orientation could either coincide or conflict with information provided by position cues. When the cues were incongruent, we found a characteristic trade-off between position and orientation information whereby position cues increasingly dominated perception as the relative uncertainty of orientation increased and vice versa. Furthermore, we found no evidence for differences in the visual processing of biological and non-biological objects, casting doubt on the claim that biological motion may be specialized in the human brain, at least in specific terms of form analysis. To explain these behavioral results quantitatively, we adopt a probabilistic template-matching model that uses Bayesian inference within local modules to estimate object shape separately from either spatial position or orientation signals. The outputs of the two modules are integrated with weights that reflect individual estimates of subjective cue reliability, and integrated over time to produce a decision about the perceived dynamics of the input data. Results of this model provided a close fit to the behavioral data, suggesting a mechanism in the human visual system that approximates rational Bayesian inference to integrate position and orientation signals in dynamic form analysis.

Food-derived sensory cues modulate longevity via distinct neuroendocrine insulin-like peptides

PubMed Central

Artan, Murat; Jeong, Dae-Eun; Lee, Dongyeop; Kim, Young-Il; Son, Heehwa G.; Husain, Zahabiya; Kim, Jinmahn; Altintas, Ozlem; Kim, Kyuhyung; Alcedo, Joy; Lee, Seung-Jae V.

2016-01-01

Environmental fluctuations influence organismal aging by affecting various regulatory systems. One such system involves sensory neurons, which affect life span in many species. However, how sensory neurons coordinate organismal aging in response to changes in environmental signals remains elusive. Here, we found that a subset of sensory neurons shortens Caenorhabditis elegans’ life span by differentially regulating the expression of a specific insulin-like peptide (ILP), INS-6. Notably, treatment with food-derived cues or optogenetic activation of sensory neurons significantly increases ins-6 expression and decreases life span. INS-6 in turn relays the longevity signals to nonneuronal tissues by decreasing the activity of the transcription factor DAF-16/FOXO. Together, our study delineates a mechanism through which environmental sensory cues regulate aging rates by modulating the activities of specific sensory neurons and ILPs. PMID:27125673

Two Persons with Multiple Disabilities Use Orientation Technology with Auditory Cues to Manage Simple Indoor Traveling

ERIC Educational Resources Information Center

Lancioni, Giulio E.; Singh, Nirbhay N.; O'Reilly, Mark F.; Sigafoos, Jeff; Campodonico, Francesca; Oliva, Doretta

2010-01-01

This study was an effort to extend the evaluation of orientation technology for promoting independent indoor traveling in persons with multiple disabilities. Two participants (adults) were included, who were to travel to activity destinations within occupational settings. The orientation system involved (a) cueing sources only at the destinations…

Effects of Visual Cues and Self-Explanation Prompts: Empirical Evidence in a Multimedia Environment

ERIC Educational Resources Information Center

Lin, Lijia; Atkinson, Robert K.; Savenye, Wilhelmina C.; Nelson, Brian C.

2016-01-01

The purpose of this study was to investigate the impacts of visual cues and different types of self-explanation prompts on learning, cognitive load, and intrinsic motivation in an interactive multimedia environment that was designed to deliver a computer-based lesson about the human cardiovascular system. A total of 126 college students were…

Integration of visual and motion cues for flight simulator requirements and ride quality investigation

NASA Technical Reports Server (NTRS)

Young, L. R.

1976-01-01

Investigations for the improvement of flight simulators are reported. Topics include: visual cues in landing, comparison of linear and nonlinear washout filters using a model of the vestibular system, and visual vestibular interactions (yaw axis). An abstract is given for a thesis on the applications of human dynamic orientation models to motion simulation.

The Structure of Meaning--A Linguistic Description.

ERIC Educational Resources Information Center

Eisenhardt, Catheryn T.

Just as a reader must bring an experiential conceptual background to the printed page, so must he bring an ability to recognize the graphic cues that signal meaning. The graphic cues or structural meaning works as a system the description of which can be outlined in three parts as the vocabulary, the structure, and the sound. What has been…

Neural Activity in the Ventral Pallidum Encodes Variation in the Incentive Value of a Reward Cue

PubMed Central

Meyer, Paul J.; Ferguson, Lindsay M.; Robinson, Terry E.; Aldridge, J. Wayne

2016-01-01

There is considerable individual variation in the extent to which reward cues are attributed with incentive salience. For example, a food-predictive conditioned stimulus (CS; an illuminated lever) becomes attractive, eliciting approach toward it only in some rats (“sign trackers,” STs), whereas others (“goal trackers,” GTs) approach the food cup during the CS period. The purpose of this study was to determine how individual differences in Pavlovian approach responses are represented in neural firing patterns in the major output structure of the mesolimbic system, the ventral pallidum (VP). Single-unit in vivo electrophysiology was used to record neural activity in the caudal VP during the performance of ST and GT conditioned responses. All rats showed neural responses to both cue onset and reward delivery but, during the CS period, STs showed greater neural activity than GTs both in terms of the percentage of responsive neurons and the magnitude of the change in neural activity. Furthermore, neural activity was positively correlated with the degree of attraction to the cue. Given that the CS had equal predictive value in STs and GTs, we conclude that neural activity in the VP largely reflects the degree to which the CS was attributed with incentive salience. SIGNIFICANCE STATEMENT Cues associated with reward can acquire motivational properties (i.e., incentive salience) that cause them to have a powerful influence on desire and motivated behavior. There are individual differences in sensitivity to reward-paired cues, with some individuals attaching greater motivational value to cues than others. Here, we investigated the neural activity associated with these individual differences in incentive salience. We found that cue-evoked neural firing in the ventral pallidum (VP) reflected the strength of incentive motivation, with the greatest neural responses occurring in individuals that demonstrated the strongest attraction to the cue. This suggests that the VP plays an important role in the process by which cues gain control over motivation and behavior. PMID:27466340

Owl Monkeys (Aotus nigriceps and A. infulatus) Follow Routes Instead of Food-Related Cues during Foraging in Captivity

PubMed Central

da Costa, Renata Souza; Bicca-Marques, Júlio César

2014-01-01

Foraging at night imposes different challenges from those faced during daylight, including the reliability of sensory cues. Owl monkeys (Aotus spp.) are ideal models among anthropoids to study the information used during foraging at low light levels because they are unique by having a nocturnal lifestyle. Six Aotus nigriceps and four A. infulatus individuals distributed into five enclosures were studied for testing their ability to rely on olfactory, visual, auditory, or spatial and quantitative information for locating food rewards and for evaluating the use of routes to navigate among five visually similar artificial feeding boxes mounted in each enclosure. During most experiments only a single box was baited with a food reward in each session. The baited box changed randomly throughout the experiment. In the spatial and quantitative information experiment there were two baited boxes varying in the amount of food provided. These baited boxes remained the same throughout the experiment. A total of 45 sessions (three sessions per night during 15 consecutive nights) per enclosure was conducted in each experiment. Only one female showed a performance suggestive of learning of the usefulness of sight to locate the food reward in the visual information experiment. Subjects showed a chance performance in the remaining experiments. All owl monkeys showed a preference for one box or a subset of boxes to inspect upon the beginning of each experimental session and consistently followed individual routes among feeding boxes. PMID:25517894

Owl monkeys (Aotus nigriceps and A. infulatus) follow routes instead of food-related cues during foraging in captivity.

PubMed

da Costa, Renata Souza; Bicca-Marques, Júlio César

2014-01-01

Foraging at night imposes different challenges from those faced during daylight, including the reliability of sensory cues. Owl monkeys (Aotus spp.) are ideal models among anthropoids to study the information used during foraging at low light levels because they are unique by having a nocturnal lifestyle. Six Aotus nigriceps and four A. infulatus individuals distributed into five enclosures were studied for testing their ability to rely on olfactory, visual, auditory, or spatial and quantitative information for locating food rewards and for evaluating the use of routes to navigate among five visually similar artificial feeding boxes mounted in each enclosure. During most experiments only a single box was baited with a food reward in each session. The baited box changed randomly throughout the experiment. In the spatial and quantitative information experiment there were two baited boxes varying in the amount of food provided. These baited boxes remained the same throughout the experiment. A total of 45 sessions (three sessions per night during 15 consecutive nights) per enclosure was conducted in each experiment. Only one female showed a performance suggestive of learning of the usefulness of sight to locate the food reward in the visual information experiment. Subjects showed a chance performance in the remaining experiments. All owl monkeys showed a preference for one box or a subset of boxes to inspect upon the beginning of each experimental session and consistently followed individual routes among feeding boxes.

Multi-Sensor Mud Detection

NASA Technical Reports Server (NTRS)

Rankin, Arturo L.; Matthies, Larry H.

2010-01-01

Robust mud detection is a critical perception requirement for Unmanned Ground Vehicle (UGV) autonomous offroad navigation. A military UGV stuck in a mud body during a mission may have to be sacrificed or rescued, both of which are unattractive options. There are several characteristics of mud that may be detectable with appropriate UGV-mounted sensors. For example, mud only occurs on the ground surface, is cooler than surrounding dry soil during the daytime under nominal weather conditions, is generally darker than surrounding dry soil in visible imagery, and is highly polarized. However, none of these cues are definitive on their own. Dry soil also occurs on the ground surface, shadows, snow, ice, and water can also be cooler than surrounding dry soil, shadows are also darker than surrounding dry soil in visible imagery, and cars, water, and some vegetation are also highly polarized. Shadows, snow, ice, water, cars, and vegetation can all be disambiguated from mud by using a suite of sensors that span multiple bands in the electromagnetic spectrum. Because there are military operations when it is imperative for UGV's to operate without emitting strong, detectable electromagnetic signals, passive sensors are desirable. JPL has developed a daytime mud detection capability using multiple passive imaging sensors. Cues for mud from multiple passive imaging sensors are fused into a single mud detection image using a rule base, and the resultant mud detection is localized in a terrain map using range data generated from a stereo pair of color cameras.

Astrophysical payload accommodation on the space station

NASA Technical Reports Server (NTRS)

Woods, B. P.

1985-01-01

Surveys of potential space station astrophysics payload requirements and existing point mount design concepts were performed to identify potential design approaches for accommodating astrophysics instruments from space station. Most existing instrument pointing systems were designed for operation from the space shuttle and it is unlikely that they will sustain their performance requirements when exposed to the space station disturbance environment. The technology exists or is becoming available so that precision pointing can be provided from the space station manned core. Development of a disturbance insensitive pointing mount is the key to providing a generic system for space station. It is recommended that the MSFC Suspended Experiment Mount concept be investigated for use as part of a generic pointing mount for space station. Availability of a shirtsleeve module for instrument change out, maintenance and repair is desirable from the user's point of view. Addition of a shirtsleeve module on space station would require a major program commitment.

Hall Current Plasma Source Having a Center-Mounted or a Surface-Mounted Cathode

NASA Technical Reports Server (NTRS)

Martinez, Rafael A. (Inventor); Moritz, Jr., Joel A. (Inventor); Williams, John D. (Inventor); Farnell, Casey C. (Inventor)

2018-01-01

A miniature Hall current plasma source apparatus having magnetic shielding of the walls from ionized plasma, an integrated discharge channel and gas distributor, an instant-start hollow cathode mounted to the plasma source, and an externally mounted keeper, is described. The apparatus offers advantages over other Hall current plasma sources having similar power levels, including: lower mass, longer lifetime, lower part count including fewer power supplies, and the ability to be continuously adjustable to lower average power levels using pulsed operation and adjustment of the pulse duty cycle. The Hall current plasma source can provide propulsion for small spacecraft that either do not have sufficient power to accommodate a propulsion system or do not have available volume to incorporate the larger propulsion systems currently available. The present low-power Hall current plasma source can be used to provide energetic ions to assist the deposition of thin films in plasma processing applications.

Army Contracting Officials Could Have Purchased Husky Mounted Detection System Spare Parts at Lower Prices (Redacted)

DTIC Science & Technology

2016-03-31

system mounted on an armored vehicle . It detects and marks landmines and other buried explosive hazards, and serves an important role in keeping...countries. Figure 1. HMDS Shown on a Husky Vehicle Source: Project Manager Close Combat Systems FOR OFFICIAL USE ONLY FOR OFFICIAL USE ONLY Introduction...Reasonable Prices From Meggitt Aircraft Braking Systems for Sole-Source Commercial Spare Parts,” May 8, 2015 Report No. DODIG-2015-103, “Summary of

The Multiple-Demand System in the Novelty of Musical Improvisation: Evidence from an MRI Study on Composers.

PubMed

Lu, Jing; Yang, Hua; He, Hui; Jeon, Seun; Hou, Changyue; Evans, Alan C; Yao, Dezhong

2017-01-01

The multiple-demand (MD) system has proven to be associated with creating structured mental programs in comprehensive behaviors, but the functional mechanisms of this system have not been clarified in the musical domain. In this study, we explored the hypothesis that the MD system is involved in a comprehensive music-related behavior known as musical improvisation. Under a functional magnetic resonance imaging (fMRI) paradigm, 29 composers were recruited to improvise melodies through visual imagery tasks according to familiar and unfamiliar cues. We found that the main regions of the MD system were significantly activated during both musical improvisation conditions. However, only a greater involvement of the intraparietal sulcus (IPS) within the MD system was shown when improvising with unfamiliar cues. Our results revealed that the MD system strongly participated in musical improvisation through processing the novelty of melodies, working memory, and attention. In particular, improvising with unfamiliar cues required more musical transposition manipulations. Moreover, both functional and structural analyses indicated evidence of neuroplasticity in MD regions that could be associated with musical improvisation training. These findings can help unveil the functional mechanisms of the MD system in musical cognition, as well as improve our understanding of musical improvisation.

The Multiple-Demand System in the Novelty of Musical Improvisation: Evidence from an MRI Study on Composers

PubMed Central

Lu, Jing; Yang, Hua; He, Hui; Jeon, Seun; Hou, Changyue; Evans, Alan C.; Yao, Dezhong

2017-01-01

The multiple-demand (MD) system has proven to be associated with creating structured mental programs in comprehensive behaviors, but the functional mechanisms of this system have not been clarified in the musical domain. In this study, we explored the hypothesis that the MD system is involved in a comprehensive music-related behavior known as musical improvisation. Under a functional magnetic resonance imaging (fMRI) paradigm, 29 composers were recruited to improvise melodies through visual imagery tasks according to familiar and unfamiliar cues. We found that the main regions of the MD system were significantly activated during both musical improvisation conditions. However, only a greater involvement of the intraparietal sulcus (IPS) within the MD system was shown when improvising with unfamiliar cues. Our results revealed that the MD system strongly participated in musical improvisation through processing the novelty of melodies, working memory, and attention. In particular, improvising with unfamiliar cues required more musical transposition manipulations. Moreover, both functional and structural analyses indicated evidence of neuroplasticity in MD regions that could be associated with musical improvisation training. These findings can help unveil the functional mechanisms of the MD system in musical cognition, as well as improve our understanding of musical improvisation. PMID:29311776

Stimulus competition mediates the joint effects of spatial and feature-based attention

PubMed Central

White, Alex L.; Rolfs, Martin; Carrasco, Marisa

2015-01-01

Distinct attentional mechanisms enhance the sensory processing of visual stimuli that appear at task-relevant locations and have task-relevant features. We used a combination of psychophysics and computational modeling to investigate how these two types of attention—spatial and feature based—interact to modulate sensitivity when combined in one task. Observers monitored overlapping groups of dots for a target change in color saturation, which they had to localize as being in the upper or lower visual hemifield. Pre-cues indicated the target's most likely location (left/right), color (red/green), or both location and color. We measured sensitivity (d′) for every combination of the location cue and the color cue, each of which could be valid, neutral, or invalid. When three competing saturation changes occurred simultaneously with the target change, there was a clear interaction: The spatial cueing effect was strongest for the cued color, and the color cueing effect was strongest at the cued location. In a second experiment, only the target dot group changed saturation, such that stimulus competition was low. The resulting cueing effects were statistically independent and additive: The color cueing effect was equally strong at attended and unattended locations. We account for these data with a computational model in which spatial and feature-based attention independently modulate the gain of sensory responses, consistent with measurements of cortical activity. Multiple responses then compete via divisive normalization. Sufficient competition creates interactions between the two cueing effects, although the attentional systems are themselves independent. This model helps reconcile seemingly disparate behavioral and physiological findings. PMID:26473316

Computational search for hypotheses concerning the endocannabinoid contribution to the extinction of fear conditioning.

PubMed

Anastasio, Thomas J

2013-01-01

Fear conditioning, in which a cue is conditioned to elicit a fear response, and extinction, in which a previously conditioned cue no longer elicits a fear response, depend on neural plasticity occurring within the amygdala. Projection neurons in the basolateral amygdala (BLA) learn to respond to the cue during fear conditioning, and they mediate fear responding by transferring cue signals to the output stage of the amygdala. Some BLA projection neurons retain their cue responses after extinction. Recent work shows that activation of the endocannabinoid system is necessary for extinction, and it leads to long-term depression (LTD) of the GABAergic synapses that inhibitory interneurons make onto BLA projection neurons. Such GABAergic LTD would enhance the responses of the BLA projection neurons that mediate fear responding, so it would seem to oppose, rather than promote, extinction. To address this paradox, a computational analysis of two well-known conceptual models of amygdaloid plasticity was undertaken. The analysis employed exhaustive state-space search conducted within a declarative programming environment. The analysis reveals that GABAergic LTD actually increases the number of synaptic strength configurations that achieve extinction while preserving the cue responses of some BLA projection neurons in both models. The results suggest that GABAergic LTD helps the amygdala retain cue memory during extinction even as the amygdala learns to suppress the previously conditioned response. The analysis also reveals which features of both models are essential for their ability to achieve extinction with some cue memory preservation, and suggests experimental tests of those features.

Computational search for hypotheses concerning the endocannabinoid contribution to the extinction of fear conditioning

PubMed Central

Anastasio, Thomas J.

2013-01-01

Fear conditioning, in which a cue is conditioned to elicit a fear response, and extinction, in which a previously conditioned cue no longer elicits a fear response, depend on neural plasticity occurring within the amygdala. Projection neurons in the basolateral amygdala (BLA) learn to respond to the cue during fear conditioning, and they mediate fear responding by transferring cue signals to the output stage of the amygdala. Some BLA projection neurons retain their cue responses after extinction. Recent work shows that activation of the endocannabinoid system is necessary for extinction, and it leads to long-term depression (LTD) of the GABAergic synapses that inhibitory interneurons make onto BLA projection neurons. Such GABAergic LTD would enhance the responses of the BLA projection neurons that mediate fear responding, so it would seem to oppose, rather than promote, extinction. To address this paradox, a computational analysis of two well-known conceptual models of amygdaloid plasticity was undertaken. The analysis employed exhaustive state-space search conducted within a declarative programming environment. The analysis reveals that GABAergic LTD actually increases the number of synaptic strength configurations that achieve extinction while preserving the cue responses of some BLA projection neurons in both models. The results suggest that GABAergic LTD helps the amygdala retain cue memory during extinction even as the amygdala learns to suppress the previously conditioned response. The analysis also reveals which features of both models are essential for their ability to achieve extinction with some cue memory preservation, and suggests experimental tests of those features. PMID:23761759

Modeling Auditory-Haptic Interface Cues from an Analog Multi-line Telephone

NASA Technical Reports Server (NTRS)

Begault, Durand R.; Anderson, Mark R.; Bittner, Rachael M.

2012-01-01

The Western Electric Company produced a multi-line telephone during the 1940s-1970s using a six-button interface design that provided robust tactile, haptic and auditory cues regarding the "state" of the communication system. This multi-line telephone was used as a model for a trade study comparison of two interfaces: a touchscreen interface (iPad)) versus a pressure-sensitive strain gauge button interface (Phidget USB interface controllers). The experiment and its results are detailed in the authors' AES 133rd convention paper " Multimodal Information Management: Evaluation of Auditory and Haptic Cues for NextGen Communication Dispays". This Engineering Brief describes how the interface logic, visual indications, and auditory cues of the original telephone were synthesized using MAX/MSP, including the logic for line selection, line hold, and priority line activation.

Investigation of UH-60A Rotor Structural Loads from Flight and Wind Tunnel Tests

DTIC Science & Technology

2016-05-19

and main rotor blades. A bifilar pendulum -type vibration absorber system was mounted on top of the hub to reduce 3/rev rotating in-plane loads. Main... pendulum weights were not attached (no 3/rev in-plane load absorption). The rotor assembly was mounted on a large test stand with its own fixed system

Lens-mount stability trade-off: a survey exemplified for DUV wafer inspection objectives

NASA Astrophysics Data System (ADS)

Bouazzam, Achmed; Erbe, Torsten; Fahr, Stephan; Werschnik, Jan

2015-09-01

The position stability of optical elements is an essential part of the tolerance budget of an optical system because its compensation would require an alignment step after the lens has left the factory. In order to achieve a given built performance the stability error contribution needs to be known and accounted for. Given a high-end lens touching the edge of technology not knowing, under- or overestimating this contribution becomes a serious cost and risk factor. If overestimated the remaining parts of the budget need to be tighter. If underestimated the total project might fail. For many mounting principles the stability benchmark is based on previous systems or information gathered by elaborated testing of complete optical systems. This renders the development of a new system into a risky endeavour, because these experiences are not sufficiently precise and tend to be not transferable when scaling of the optical elements is intended. This contribution discusses the influences of different optical mounting concepts on the position stability using the example of high numerical aperture (HNA) inspection lenses working in the deep ultraviolet (DUV) spectrum. A method to investigate the positional stability is presented for selected mounting examples typical for inspection lenses.

Instrument-mounted displays for reducing cognitive load during surgical navigation.

PubMed

Herrlich, Marc; Tavakol, Parnian; Black, David; Wenig, Dirk; Rieder, Christian; Malaka, Rainer; Kikinis, Ron

2017-09-01

Surgical navigation systems rely on a monitor placed in the operating room to relay information. Optimal monitor placement can be challenging in crowded rooms, and it is often not possible to place the monitor directly beside the situs. The operator must split attention between the navigation system and the situs. We present an approach for needle-based interventions to provide navigational feedback directly on the instrument and close to the situs by mounting a small display onto the needle. By mounting a small and lightweight smartwatch display directly onto the instrument, we are able to provide navigational guidance close to the situs and directly in the operator's field of view, thereby reducing the need to switch the focus of view between the situs and the navigation system. We devise a specific variant of the established crosshair metaphor suitable for the very limited screen space. We conduct an empirical user study comparing our approach to using a monitor and a combination of both. Results from the empirical user study show significant benefits for cognitive load, user preference, and general usability for the instrument-mounted display, while achieving the same level of performance in terms of time and accuracy compared to using a monitor. We successfully demonstrate the feasibility of our approach and potential benefits. With ongoing technological advancements, instrument-mounted displays might complement standard monitor setups for surgical navigation in order to lower cognitive demands and for improved usability of such systems.