Sample records for mrr reactor

  1. MRR and TWR evaluation on electrical discharge machining of Ti-6Al-4V using tungsten : copper composite electrode

    NASA Astrophysics Data System (ADS)

    Prasanna, J.; Rajamanickam, S.; Amith Kumar, O.; Karthick Raj, G.; Sathya Narayanan, P. V. V.

    2017-05-01

    In this paper Ti-6Al-4V used as workpiece material and it is keenly seen in variety of field including medical, chemical, marine, automotive, aerospace, aviation, electronic industries, nuclear reactor, consumer products etc., The conventional machining of Ti-6Al-4V is very difficult due to its distinctive properties. The Electrical Discharge Machining (EDM) is right choice of machining this material. The tungsten copper composite material is employed as tool material. The gap voltage, peak current, pulse on time and duty factor is considered as the machining parameter to analyze the machining characteristics Material Removal Rate (MRR) and Tool Wear Rate (TWR). The Taguchi method is provided to work for finding the significant parameter of EDM. It is found that for MRR significant parameters rated in the following order Gap Voltage, Pulse On-Time, Peak Current and Duty Factor. On the other hand for TWR significant parameters are listed in line of Gap Voltage, Duty Factor, Peak Current and Pulse On-Time.

  2. Candida albicans Swi/Snf and Mediator Complexes Differentially Regulate Mrr1-Induced MDR1 Expression and Fluconazole Resistance.

    PubMed

    Liu, Zhongle; Myers, Lawrence C

    2017-11-01

    Long-term azole treatment of patients with chronic Candida albicans infections can lead to drug resistance. Gain-of-function (GOF) mutations in the transcription factor Mrr1 and the consequent transcriptional activation of MDR1 , a drug efflux coding gene, is a common pathway by which this human fungal pathogen acquires fluconazole resistance. This work elucidates the previously unknown downstream transcription mechanisms utilized by hyperactive Mrr1. We identified the Swi/Snf chromatin remodeling complex as a key coactivator for Mrr1, which is required to maintain basal and induced open chromatin, and Mrr1 occupancy, at the MDR1 promoter. Deletion of snf2 , the catalytic subunit of Swi/Snf, largely abrogates the increases in MDR1 expression and fluconazole MIC observed in MRR1 GOF mutant strains. Mediator positively and negatively regulates key Mrr1 target promoters. Deletion of the Mediator tail module med3 subunit reduces, but does not eliminate, the increased MDR1 expression and fluconazole MIC conferred by MRR1 GOF mutations. Eliminating the kinase activity of the Mediator Ssn3 subunit suppresses the decreased MDR1 expression and fluconazole MIC of the snf2 null mutation in MRR1 GOF strains. Ssn3 deletion also suppresses MDR1 promoter histone displacement defects in snf2 null mutants. The combination of this work with studies on other hyperactive zinc cluster transcription factors that confer azole resistance in fungal pathogens reveals a complex picture where the induction of drug efflux pump expression requires the coordination of multiple coactivators. The observed variations in transcription factor and target promoter dependence of this process may make the search for azole sensitivity-restoring small molecules more complicated. Copyright © 2017 American Society for Microbiology.

  3. Social security status and mortality in Belgian and Spanish male workers.

    PubMed

    Duran, Xavier; Vanroelen, Christophe; Deboosere, Patrick; Benavides, Fernando G

    2016-01-01

    To assess differences in mortality rates between social security statuses in two independent samples of Belgian and Spanish male workers. Study of two retrospective cohorts (Belgium, n=23,607; Spain, n=44,385) of 50-60 year old male employees with 4 years of follow-up. Mortality rate ratios (MRR) were estimated using Poisson regression models. Mortality for subjects with permanent disability was higher than for the employed, for both Belgium [MRR=4.56 (95% CI: 2.88-7.21)] and Spain [MRR=7.15 (95% CI: 5.37-9.51)]. For the unemployed/early retirees, mortality was higher in Spain [MRR=1.64 (95% CI: 1.24-2.17)] than in Belgium [MRR=0.88 (95% CI: 0.46-1.71)]. MRR differences between Belgium and Spain for unemployed workers could be partly explained because of differences between the two social security systems. Future studies should further explore mortality differences between countries with different social security systems. Copyright © 2016 SESPAS. Published by Elsevier Espana. All rights reserved.

  4. SEMICONDUCTOR TECHNOLOGY Effects of the reciprocating parameters of the carrier on material removal rate and non-uniformity in CMP

    NASA Astrophysics Data System (ADS)

    Cailing, Wang; Renke, Kang; Zhuji, Jin; Dongming, Guo

    2010-12-01

    Based on the Preston equation, the mathematical model of the material removal rate (MRR), aiming at a line-orbit chemical mechanical polisher, is established. The MRR and the material removal non-uniformity (MRNU) are numerically calculated by MATLAB, and the effects of the reciprocating parameters on the MRR and the MRNU are discussed. It is shown that the smaller the inclination angle and the larger the amplitude, the higher the MRR and the lower the MRNU. The reciprocating speed of the carrier plays a minor role to improve the MRR and decrease the MRNU. The results provide a guide for the design of a polisher and the determination of a process in line-orbit chemical mechanical polishing.

  5. Comparison of injury mortality risk in motor vehicle crash versus other etiologies.

    PubMed

    Kilgo, Patrick D; Weaver, Ashley A; Barnard, Ryan T; Love, Timothy P; Stitzel, Joel D

    2014-06-01

    The mortality risk ratio (MRR), a measure of the proportion of people who died that sustained a given injury, is reported to be among the most powerful discriminators of mortality following trauma. The primary aim was to determine whether mechanistic differences exist and are quantifiable when comparing MRR-based injury severity across two broadly defined etiologies (motor vehicle crash (MVC) versus non-MVC) for the clarification of important injury types that have some room for improvement by emergency treatment and vehicle design. All International Classification of Diseases, 9th revision (ICD-9) coded injuries in the National Trauma Data Bank (NTDB) database were stratified into MVC and non-MVC groups and the MRR for each injury was computed within each group. Injuries were classified as 11 different types for MRR comparison between etiologies. Overall, MRRs for specific injuries were 10-18% lower for MVC compared to non-MVC etiologies. MVCs however produced much higher mean MRRs for crushing injuries (0.184 versus 0.072) and internal injuries to the thorax, abdomen, and pelvis (0.200 versus 0.169). Non-MVCs produced much higher MRRs for intracranial injuries (0.199 versus 0.250). Analysis of the top 95% most frequent MVC injuries revealed higher MVC MRR values for 78% of the injuries with MRR ratios indicating an average 50% increase in a given injury's MRR when MVC was the etiology. Addressing the large differences in MRR in between etiologies for identical injuries could provide a reduction in fatalities and may be important to patient triage and vehicle safety design. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Analysis of the Material Removal Rate in Magnetic Abrasive Finishing of Thin Film Coated Pyrex Glass

    NASA Astrophysics Data System (ADS)

    Lee, Hee Hwan; Lee, Seoung Hwan

    The material removal rate (MRR) during precision finishing/polishing is a key factor, which dictates the process performance. Moreover, the MRR or wear rate is closely related to the material/part reliability. For nanoscale patterning and/or planarization on nano-order thickness coatings, the prediction and in-process monitoring of the MRR is necessary, because the process is not characterizable due to size effects and material property/process condition variations as a result of the coating/substrate interactions. The purpose of this research was to develop a practical methodology for the prediction and in-process monitoring of MRR during nanoscale finishing of coated surfaces. Using a specially designed magnetic abrasive finishing (MAF) and acoustic emission (AE) monitoring setup, experiments were carried out on indium-zinc-oxide (IZO) coated Pyrex glasses. After a given polishing time interval, AFM indentation was conducted for each workpiece sample to measure the adhesion force variations of the coating layers (IZO), which are directly related to the MRR changes. The force variation and AE monitoring data were compared to the MRR calculated form the surface measurement (Nanoview) results. The experimental results demonstrate strong correlations between AFM indentation and MRR measurement data. In addition, the monitored AE signals show sensitivity of the material structure variations of the coating layer, as the polishing progresses.

  7. South Carolina Commission on Higher Education Mission Resource Requirements (MRR), FY 2007-2008

    ERIC Educational Resources Information Center

    South Carolina Commission on Higher Education, 2007

    2007-01-01

    The Mission Resource Requirement (MRR) represents the level of funding necessary for an institution given its mission, size, and complexity of programs, based on regional and national norms, and the amount of the previous year's appropriation. This document is the MRR for the South Carolina Commission on Higher Education for Fiscal Year 2007-2008.…

  8. Observation of snowfall with a low-power FM-CW K-band radar (Micro Rain Radar)

    NASA Astrophysics Data System (ADS)

    Kneifel, Stefan; Maahn, Maximilian; Peters, Gerhard; Simmer, Clemens

    2011-06-01

    Quantifying snowfall intensity especially under arctic conditions is a challenge because wind and snow drift deteriorate estimates obtained from both ground-based gauges and disdrometers. Ground-based remote sensing with active instruments might be a solution because they can measure well above drifting snow and do not suffer from flow distortions by the instrument. Clear disadvantages are, however, the dependency of e.g. radar returns on snow habit which might lead to similar large uncertainties. Moreover, high sensitivity radars are still far too costly to operate in a network and under harsh conditions. In this paper we compare returns from a low-cost, low-power vertically pointing FM-CW radar (Micro Rain Radar, MRR) operating at 24.1 GHz with returns from a 35.5 GHz cloud radar (MIRA36) for dry snowfall during a 6-month observation period at an Alpine station (Environmental Research Station Schneefernerhaus, UFS) at 2,650 m height above sea level. The goal was to quantify the potential and limitations of the MRR in relation to what is achievable by a cloud radar. The operational MRR procedures to derive standard radar variables like effective reflectivity factor ( Z e) or the mean Doppler velocity ( W) had to be modified for snowfall since the MRR was originally designed for rain observations. Since the radar returns from snowfall are weaker than from comparable rainfall, the behavior of the MRR close to its detection threshold has been analyzed and a method is proposed to quantify the noise level of the MRR based on clear sky observations. By converting the resulting MRR- Z e into 35.5 GHz equivalent Z e values, a remaining difference below 1 dBz with slightly higher values close to the noise threshold could be obtained. Due to the much higher sensitivity of MIRA36, the transition of the MRR from the true signal to noise can be observed, which agrees well with the independent clear sky noise estimate. The mean Doppler velocity differences between both radars are below 0.3 ms-1. The distribution of Z e values from MIRA36 are finally used to estimate the uncertainty of retrieved snowfall and snow accumulation with the MRR. At UFS low snowfall rates missed by the MRR are negligible when comparing snow accumulation, which were mainly caused by intensities between 0.1 and 0.8 mm h-1. The MRR overestimates the total snow accumulation by about 7%. This error is much smaller than the error caused by uncertain Z e-snowfall rate relations, which would affect the MIRA36 estimated to a similar degree.

  9. Biosensing Using Microring Resonator Interferograms

    PubMed Central

    Hsu, Shih-Hsiang; Yang, Yung-Chia; Su, Yu-Hou; Wang, Sheng-Min; Huang, Shih-An; Lin, Ching-Yu

    2014-01-01

    Optical low-coherence interferometry (OLCI) takes advantage of the variation in refractive index in silicon-wire microring resonator (MRR) effective lengths to perform glucose biosensing using MRR interferograms. The MRR quality factor (Q), proportional to the effective length, could be improved using the silicon-wire propagation loss and coupling ratio from the MRR coupler. Our study showed that multimode interference (MMI) performed well in broad band response, but the splitting ratio drifted to 75/25 due to the stress issue. The glucose sensing sensitivity demonstrated 0.00279 meter per refractive-index-unit (RIU) with a Q factor of ∼30,000 under transverse electric polarization. The 1,310 nm DFB laser was built in the OLCI system as the optical ruler achieving 655 nm characterization accuracy. The lowest sensing limitation was therefore 2 × 10−4 RIU. Moreover, the MRR effective length from the glucose sensitivity could be utilized to experimentally demonstrate the silicon wire effective refractive index with a width of 0.45 μm and height of 0.26 μm. PMID:24434876

  10. Magnetorheological finishing of chemical-vapor deposited zinc sulfide via chemically and mechanically modified fluids.

    PubMed

    Salzman, Sivan; Romanofsky, Henry J; Giannechini, Lucca J; Jacobs, Stephen D; Lambropoulos, John C

    2016-02-20

    We describe the anisotropy in the material removal rate (MRR) of the polycrystalline, chemical-vapor deposited zinc sulfide (ZnS). We define the polycrystalline anisotropy via microhardness and chemical erosion tests for four crystallographic orientations of ZnS: (100), (110), (111), and (311). Anisotropy in the MRR was studied under magnetorheological finishing (MRF) conditions. Three chemically and mechanically modified magnetorheological (MR) fluids at pH values of 4, 5, and 6 were used to test the MRR variations among the four single-crystal planes. When polishing the single-crystal planes and the polycrystalline with pH 5 and pH 6 MR fluids, variations were found in the MRR among the four single-crystal planes and surface artifacts were observed on the polycrystalline material. When polishing the single-crystal planes and the polycrystalline with the modified MR fluid at pH 4, however, minimal variation was observed in the MRR among the four orientations and a reduction in surface artifacts was achieved on the polycrystalline material.

  11. Magnetoresistance in single-electron transistors comprising a superconducting island with ferromagnetic leads

    NASA Astrophysics Data System (ADS)

    Mizugaki, Yoshinao; Takiguchi, Masashi; Tamura, Nobuyuki; Shimada, Hiroshi

    2018-03-01

    We report electric and magnetic field responses of single-electron transistors (SETs) comprising a superconducting island with ferromagnetic (FM) leads. We fabricated two SETs, one of which had relatively high resistance and the other had relatively low resistance. The SETs had two states for the gate charge: SET-ON or SET-OFF. They also had two states for the FM lead magnetization: parallel (P) or anti-parallel (AP) configuration. Current-voltage characteristics of four SET states (“P & SET-ON,” “P & SET-OFF,” “AP & SET-ON,” and “AP & SET-OFF”) were measured at approximately 0.1 K in a compact dilution refrigerator. Magnetoresistance ratio (MRR) values were obtained for the SET-ON and SET-OFF states, respectively. The higher-resistance SET1 exhibited positive MRR values for all measured bias voltages. The MRR enhancement was confirmed for the SET-OFF state, which agreed well with the co-tunneling model. The lower-resistance SET2, on the other hand, exhibited negative and positive MRR values for higher and lower bias voltage conditions, respectively. The bias voltage for the MRR polarity reversal was changed by the gate voltage. It was also confirmed that the co-tunneling model was partially valid for negative MRR values.

  12. Mortality-based Quantification of Injury Severity for Frequently Occurring Motor Vehicle Crash Injuries

    PubMed Central

    Weaver, Ashley A.; Barnard, Ryan T.; Kilgo, Patrick D.; Martin, R. Shayn; Stitzel, Joel D.

    2013-01-01

    The study purpose was to develop mortality-based metrics of injury severity for frequent motor vehicle crash (MVC) injuries. Injury severity was quantified with mortality-based metrics for 240 injuries comprising the top 95% most frequently occurring AIS 2+ injuries in the National Automotive Sampling System – Crashworthiness Data System (NASS-CDS) 2000–2011. Mortality risk ratios (MRRs) were computed by dividing the number of deaths by occurrences for each of the 240 injuries using National Trauma Data Bank Research Data System (NTDB-RDS) MVC cases. MRRMAIS was computed using only patients with a maximum AIS (MAIS) equal to the AIS severity of a given injury. Each injury had an associated MRR and MRRMAIS which ranged from zero (0% mortality representing low severity) to one (100% or universal mortality representing high severity). Injuries with higher MRR and MRRMAIS values are considered more severe because they resulted in a greater proportion of deaths among injured patients. The results illustrated an overall positive trend between AIS severity and the MRR and MRRMAIS values as expected, but showed large variations in MRR and MRRMAIS for some injuries of the same AIS severity. Mortality differences up to 83% (MRR) and 54% (MRRMAIS) were observed for injuries of the same AIS severity. The MRR-based measures of injury severity indicate that some lower AIS severity injuries may result in as many deaths as higher AIS severity injuries. This data-driven determination of injury severity using MRR and MRRMAIS provides a supplement or an alternative to AIS severity classification. PMID:24406961

  13. Mortality-based Quantification of Injury Severity for Frequently Occurring Motor Vehicle Crash Injuries.

    PubMed

    Weaver, Ashley A; Barnard, Ryan T; Kilgo, Patrick D; Martin, R Shayn; Stitzel, Joel D

    The study purpose was to develop mortality-based metrics of injury severity for frequent motor vehicle crash (MVC) injuries. Injury severity was quantified with mortality-based metrics for 240 injuries comprising the top 95% most frequently occurring AIS 2+ injuries in the National Automotive Sampling System - Crashworthiness Data System (NASS-CDS) 2000-2011. Mortality risk ratios (MRRs) were computed by dividing the number of deaths by occurrences for each of the 240 injuries using National Trauma Data Bank Research Data System (NTDB-RDS) MVC cases. MRRMAIS was computed using only patients with a maximum AIS (MAIS) equal to the AIS severity of a given injury. Each injury had an associated MRR and MRRMAIS which ranged from zero (0% mortality representing low severity) to one (100% or universal mortality representing high severity). Injuries with higher MRR and MRRMAIS values are considered more severe because they resulted in a greater proportion of deaths among injured patients. The results illustrated an overall positive trend between AIS severity and the MRR and MRRMAIS values as expected, but showed large variations in MRR and MRRMAIS for some injuries of the same AIS severity. Mortality differences up to 83% (MRR) and 54% (MRRMAIS) were observed for injuries of the same AIS severity. The MRR-based measures of injury severity indicate that some lower AIS severity injuries may result in as many deaths as higher AIS severity injuries. This data-driven determination of injury severity using MRR and MRRMAIS provides a supplement or an alternative to AIS severity classification.

  14. Residential exposure to pesticides and childhood leukaemia: a systematic review and meta-analysis.

    PubMed

    Van Maele-Fabry, Geneviève; Lantin, Anne-Catherine; Hoet, Perrine; Lison, Dominique

    2011-01-01

    To conduct a systematic review of published studies on the association between residential/household/domestic exposure to pesticides and childhood leukaemia, and to provide a quantitative estimate of the risk. Publications in English were searched in MEDLINE (1966-31 December 2009) and from the reference list of identified publications. Extraction of relative risk (RR) estimates was performed independently by 2 authors using predefined inclusion criteria. Meta-rate ratio estimates (mRR) were calculated according to fixed and random-effect models. Separate analyses were conducted after stratification for exposure time windows, residential exposure location, biocide category and type of leukaemia. RR estimates were extracted from 13 case-control studies published between 1987 and 2009. Statistically significant associations with childhood leukaemia were observed when combining all studies (mRR: 1.74, 95% CI: 1.37-2.21). Exposure during and after pregnancy was positively associated with childhood leukaemia, with the strongest risk for exposure during pregnancy (mRR: 2.19, 95% CI: 1.92-2.50). Other stratifications showed the greatest risk estimates for indoor exposure (mRR: 1.74, 95% CI: 1.45-2.09), for exposure to insecticides (mRR: 1.73, 95% CI: 1.33-2.26) as well as for acute non-lymphocytic leukaemia (ANLL) (mRR: 2.30, 95% CI: 1.53-3.45). Outdoor exposure and exposure of children to herbicides (after pregnancy) were not significantly associated with childhood leukaemia (mRR: 1.21, 95% CI: 0.97-1.52; mRR: 1.16, 95% CI: 0.76-1.76, respectively). Our findings support the assumption that residential pesticide exposure may be a contributing risk factor for childhood leukaemia but available data were too scarce for causality ascertainment. It may be opportune to consider preventive actions, including educational measures, to decrease the use of pesticides for residential purposes and particularly the use of indoor insecticides during pregnancy. Copyright © 2010 Elsevier Ltd. All rights reserved.

  15. Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats.

    PubMed

    Taylor, Natalie C; Li, Aihua; Nattie, Eugene E

    2005-07-15

    Serotonergic neurones in the mammalian medullary raphe region (MRR) have been implicated in central chemoreception and the modulation of the ventilatory response to hypercapnia, and may also be involved in the ventilatory response to hypoxia. In this study, we ask whether ventilatory responses across arousal states are affected when the 5-hydroxytryptamine 1A receptor (5-HT1A) agonist (R)-(+)-8-hydroxy-2(di-n-propylamino)tetralin (DPAT) is microdialysed into the MRR of the unanaesthetized adult rat. Microdialysis of 1, 10 and 30 mM DPAT into the MRR significantly decreased absolute ventilation values(VE) during 7% CO2 breathing by 21%, 19% and 30%, respectively, in wakefulness compared to artificial cerebrospinal fluid (aCSF) microdialysis, due to decreases in tidal volume (VT) and not in frequency (f), similar to what occurred during non-rapid eye movement (NREM) sleep. The concentration-dependence of the hypercapnic ventilatory effect might be due to differences in tissue distribution of DPAT. DPAT (30 mM) changed room air breathing pattern by increasing f and decreasing VT. As evidenced by a sham control group, repeated experimentation and microdialysis of aCSF alone had no effect on the ventilatory response to 7% CO2 during wakefulness or sleep. Unlike during hypercapnia, microdialysis of 30 mM DPAT into the MRR did not change the ventilatory response to 10% O2. Additionally, 10 and 30 mM DPAT MRR microdialysis decreased body temperature, and 30 mM DPAT increased the percentage of experimental time in wakefulness. We conclude that serotonergic activity in the MRR plays a role in the ventilatory response to hypercapnia, but not to hypoxia, and that MRR 5-HT1A receptors are also involved in thermoregulation and arousal.

  16. A Single-Domain Response Regulator Functions as an Integrating Hub To Coordinate General Stress Response and Development in Alphaproteobacteria

    PubMed Central

    2018-01-01

    ABSTRACT The alphaproteobacterial general stress response is governed by a conserved partner-switching mechanism that is triggered by phosphorylation of the response regulator PhyR. In the model organism Caulobacter crescentus, PhyR was proposed to be phosphorylated by the histidine kinase PhyK, but biochemical evidence in support of such a role of PhyK is missing. Here, we identify a single-domain response regulator, MrrA, that is essential for general stress response activation in C. crescentus. We demonstrate that PhyK does not function as a kinase but accepts phosphoryl groups from MrrA and passes them on to PhyR, adopting the role of a histidine phosphotransferase. MrrA is phosphorylated by at least six histidine kinases that likely serve as stress sensors. MrrA also transfers phosphate to LovK, a histidine kinase involved in C. crescentus holdfast production and attachment, which also negatively regulates the general stress response. We show that LovK together with the response regulator LovR acts as a phosphate sink to redirect phosphate flux away from the PhyKR branch. In agreement with the biochemical data, an mrrA mutant is unable to activate the general stress response and shows a hyperattachment phenotype, which is linked to decreased expression of the major holdfast inhibitory protein HfiA. We propose that MrrA serves as a central phosphorylation hub that coordinates the general stress response with C. crescentus development and other adaptive behaviors. The characteristic bow-tie architecture of this phosphorylation network with MrrA as the central knot may expedite the evolvability and species-specific niche adaptation of this group of bacteria. PMID:29789370

  17. Magnetorheological finishing of chemical-vapor deposited zinc sulfide via chemically and mechanically modified fluids

    DOE PAGES

    Salzman, Sivan; Romanofsky, Henry J.; Giannechini, Lucca J.; ...

    2016-02-19

    In this study, we describe the anisotropy in the material removal rate (MRR) of the polycrystalline, chemical-vapor deposited zinc sulfide (ZnS).We define the polycrystalline anisotropy via microhardness and chemical erosion tests for four crystallographic orientations of ZnS: (100), (110), (111), and (311). Anisotropy in the MRR was studied under magnetorheological finishing (MRF) conditions. Three chemically and mechanically modified magnetorheological (MR) fluids at pH values of 4, 5, and 6 were used to test the MRR variations among the four single-crystal planes. When polishing the single-crystal planes and the polycrystalline with pH 5 and pH 6MR fluids, variations were found inmore » the MRR among the four single-crystal planes and surface artifacts were observed on the polycrystalline material. When polishing the single-crystal planes and the polycrystalline with the modified MR fluid at pH 4, however, minimal variation was observed in the MRR among the four orientations and a reduction in surface artifacts was achieved on the polycrystalline material.« less

  18. Individual- and area-level characteristics associated with alcohol-related mortality among adult Lithuanian males: A multilevel analysis based on census-linked data.

    PubMed

    Grigoriev, Pavel; Jasilionis, Domantas; Stumbrys, Daumantas; Stankūnienė, Vladislava; Shkolnikov, Vladimir M

    2017-01-01

    Although excessive alcohol-related mortality in the post-Soviet countries remains the major public health threat, determinants of this phenomenon are still poorly understood. We assess simultaneously individual- and area-level factors associated with an elevated risk of alcohol-related mortality among Lithuanian males aged 30-64. Our analysis is based on a census-linked dataset containing information on individual- and area-level characteristics and death events which occurred between March 1st, 2011 and December 31st, 2013. We limit the analysis to a few causes of death which are directly linked to excessive alcohol consumption: accidental poisonings by alcohol (X45) and liver cirrhosis (K70 and K74). Multilevel Poisson regression models with random intercepts are applied to estimate mortality rate ratios (MRR). The selected individual-level characteristics are important predictors of alcohol-related mortality, whereas area-level variables show much less pronounced or insignificant effects. Compared to married men, never married (MRR = 1.9, CI:1.6-2.2), divorced (MRR = 2.6, CI:2.3-2.9), and widowed (MRR = 2.4, CI: 1.8-3.1) men are disadvantaged groups. Men who have the lowest level of educational attainment have the highest mortality risk (MRR = 1.7 CI:1.4-2.1). Being unemployed is associated with a five-fold risk of alcohol-related death (MRR = 5.1, CI: 4.4-5.9), even after adjusting for all other individual variables. Lithuanian males have an advantage over Russian (MRR = 1.3, CI:1.1-1.6) and Polish (MRR = 1.8, CI: 1.5-2.2) males. After adjusting for all individual characteristics, only two out of seven area-level variables-i.e., the share of ethnic minorities in the population and the election turnout-have statistically significant direct associations. These variables contribute to a higher risk of alcohol-related mortality at the individual level. The huge and increasing socio-economic disparities in alcohol-related mortality indicate that recently implemented anti-alcohol measures in Lithuania should be reinforced by specific measures targeting the most disadvantaged population groups and geographical areas.

  19. Enhancing malaria diagnosis through microfluidic cell enrichment and magnetic resonance relaxometry detection

    NASA Astrophysics Data System (ADS)

    Fook Kong, Tian; Ye, Weijian; Peng, Weng Kung; Wei Hou, Han; Marcos; Preiser, Peter Rainer; Nguyen, Nam-Trung; Han, Jongyoon

    2015-06-01

    Despite significant advancements over the years, there remains an urgent need for low cost diagnostic approaches that allow for rapid, reliable and sensitive detection of malaria parasites in clinical samples. Our previous work has shown that magnetic resonance relaxometry (MRR) is a potentially highly sensitive tool for malaria diagnosis. A key challenge for making MRR based malaria diagnostics suitable for clinical testing is the fact that MRR baseline fluctuation exists between individuals, making it difficult to detect low level parasitemia. To overcome this problem, it is important to establish the MRR baseline of each individual while having the ability to reliably determine any changes that are caused by the infection of malaria parasite. Here we show that an approach that combines the use of microfluidic cell enrichment with a saponin lysis before MRR detection can overcome these challenges and provide the basis for a highly sensitive and reliable diagnostic approach of malaria parasites. Importantly, as little as 0.0005% of ring stage parasites can be detected reliably, making this ideally suited for the detection of malaria parasites in peripheral blood obtained from patients. The approaches used here are envisaged to provide a new malaria diagnosis solution in the near future.

  20. Continuously tunable photonic fractional Hilbert transformer using a high-contrast germanium-doped silica-on-silicon microring resonator.

    PubMed

    Shahoei, Hiva; Dumais, Patrick; Yao, Jianping

    2014-05-01

    We propose and experimentally demonstrate a continuously tunable fractional Hilbert transformer (FHT) based on a high-contrast germanium-doped silica-on-silicon (SOS) microring resonator (MRR). The propagation loss of a high-contrast germanium-doped SOS waveguide can be very small (0.02 dB/cm) while the lossless bend radius can be less than 1 mm. These characteristics lead to the fabrication of an MRR with a high Q-factor and a large free-spectral range (FSR), which is needed to implement a Hilbert transformer (HT). The SOS MRR is strongly polarization dependent. By changing the polarization direction of the input signal, the phase shift introduced at the center of the resonance spectrum is changed. The tunable phase shift at the resonance wavelength can be used to implement a tunable FHT. A germanium-doped SOS MRR with a high-index contrast of 3.8% is fabricated. The use of the fabricated MRR for the implementation of a tunable FHT with tunable orders at 1, 0.85, 0.95, 1.05, and 1.13 for a Gaussian pulse with the temporal full width at half-maximum of 80 ps is experimentally demonstrated.

  1. Improvement of vertical profiles of raindrop size distribution from micro rain radar using 2D video disdrometer measurements

    NASA Astrophysics Data System (ADS)

    Adirosi, E.; Baldini, L.; Roberto, N.; Gatlin, P.; Tokay, A.

    2016-03-01

    A measurement scheme aimed at investigating precipitation properties based on collocated disdrometer and profiling instruments is used in many experimental campaigns. Raindrop size distribution (RSD) estimated by disdrometer is referred to the ground level; the collocated profiling instrument is supposed to provide complementary estimation at different heights of the precipitation column above the instruments. As part of the Special Observation Period 1 of the HyMeX (Hydrological Cycle in the Mediterranean Experiment) project, conducted between 5 September and 6 November 2012, a K-band vertically pointing micro rain radar (MRR) and a 2D video disdrometer (2DVD) were installed close to each other at a site in the historic center of Rome (Italy). The raindrop size distributions collected by 2D video disdrometer are considered to be fairly accurate within the typical sizes of drops. Vertical profiles of raindrop sizes up to 1085 m are estimated from the Doppler spectra measured by the micro rain radar with a height resolution of 35 m. Several issues related to vertical winds, attenuation correction, Doppler spectra aliasing, and range-Doppler ambiguity limit the performance of MRR in heavy precipitation or in convection, conditions that frequently occur in late summer or in autumn in Mediterranean regions. In this paper, MRR Doppler spectra are reprocessed, exploiting the 2DVD measurements at ground to estimate the effects of vertical winds at 105 m (the most reliable MRR lower height), in order to provide a better estimation of vertical profiles of raindrop size distribution from MRR spectra. Results show that the reprocessing procedure leads to a better agreement between the reflectivity computed at 105 m from the reprocessed MRR spectra and that obtained from the 2DVD data. Finally, vertical profiles of MRR-estimated RSDs and their relevant moments (namely median volume diameter and reflectivity) are presented and discussed in order to investigate the microstructure of rain both in stratiform and convective conditions.

  2. A widely tunable dual-wavelength based on a microring resonator filter device

    NASA Astrophysics Data System (ADS)

    Amiri, Iraj S.; Ariannejad, M. M.; Tiu, Z. C.; Ooi, S. I.; Aidit, S. N.; Alizadeh, F.; Yupapin, P.

    2018-06-01

    We demonstrate a stable, tunable dual-wavelength (DW) generated by launching an in-house built supercontinuum (SC) into an add-drop microring resonator (MRR). The MRR is fabricated from a silicon–nitrogen–oxygen substrate. The frequency comb of the filtered SC is obtained with an experimental free spectral range (FSR) from 0.39 to 0.46 nm corresponding to 48.7–57 GHz within the wavelength range 1520–1660 nm. The stability of a generated DW within the ranges 1561.16 and 1561.57 nm over 120 min is examined, where high, stable DW with a very low power fluctuation is achieved. This work has demonstrated the use of waveguide based MRR in the fiber laser system, and a remarkable flat and low power fluctuations frequency comb is achieved using the in-house built SC source and MRR.

  3. Advances in Molecular Rotational Spectroscopy for Applied Science

    NASA Astrophysics Data System (ADS)

    Harris, Brent; Fields, Shelby S.; Pulliam, Robin; Muckle, Matt; Neill, Justin L.

    2017-06-01

    Advances in chemical sensitivity and robust, solid-state designs for microwave/millimeter-wave instrumentation compel the expansion of molecular rotational spectroscopy as research tool into applied science. It is familiar to consider molecular rotational spectroscopy for air analysis. Those techniques for molecular rotational spectroscopy are included in our presentation of a more broad application space for materials analysis using Fourier Transform Molecular Rotational Resonance (FT-MRR) spectrometers. There are potentially transformative advantages for direct gas analysis of complex mixtures, determination of unknown evolved gases with parts per trillion detection limits in solid materials, and unambiguous chiral determination. The introduction of FT-MRR as an alternative detection principle for analytical chemistry has created a ripe research space for the development of new analytical methods and sampling equipment to fully enable FT-MRR. We present the current state of purpose-built FT-MRR instrumentation and the latest application measurements that make use of new sampling methods.

  4. Do incident and new subsequent cases of non-melanoma skin cancer registered in a Danish prospective cohort study have different 10-year mortality?

    PubMed

    Jensen, Annette Østergaard; Olesen, Anne Braae; Dethlefsen, Claus; Sørensen, Henrik Toft

    2007-01-01

    The Danish Gerda Frentz Cohort (GFC) was created for registering all incident and new subsequent cases of non-melanoma skin cancer (NMSC) among patients seen by Danish dermatologists in 1995. We have recently found, in this cohort, a lower 10-year mortality than in the general population in patients with basal cell carcinoma (BCC). Differences in mortality between incident and new subsequent cases, incomplete registration or selection bias may be responsible for this finding. We aimed to quantify differences in mortality between incident and new subsequent cases of NMSC in the GFC and to compare mortality among incident cases recorded in the GFC and those recorded in the Danish Cancer Registry (DCR). We followed 10,830 skin cancer patients and 106,696 age-, gender- and residence-matched population controls through 2006 and computed their cumulative mortality and mortality rate ratio (MRR). One-, 5-, and 10-year cumulative mortality of incident and new subsequent cases of BCC and SCC in the GFC were similar. Likewise, MRR for incident BCC (MRR=0.91; 95% CI 0.84-0.98) and incident SCC (MRR=1.29; 95% CI 1.05-1.56) among patients registered in the GFC were similar to their counterparts in the DCR (MRR=0.96; 95% CI 0.91-1.00 and MRR=1.36; 95% CI 1.22-1.52). Mortality of incident and new subsequent cases of NMSC was similar and thus did not explain the reduced mortality of BCC patients.

  5. Educational inequality in cancer mortality: a record linkage study of over 35 million Italians.

    PubMed

    Alicandro, Gianfranco; Frova, Luisa; Sebastiani, Gabriella; El Sayed, Iman; Boffetta, Paolo; La Vecchia, Carlo

    2017-09-01

    Large studies are needed to evaluate socioeconomic inequality for site-specific cancer mortality. We conducted a longitudinal census-based national study to quantify the relative inequality in cancer mortality among educational levels in Italy. We linked the 2011 Italian census with the 2012 and 2013 death registries. Educational inequality in overall cancer and site-specific cancer mortality were evaluated by computing the mortality rate ratio (MRR). A total of 35,708,445 subjects aged 30-74 years and 147,981 cancer deaths were registered. Compared to the lowest level of education (none or primary school), the MRR for all cancers in the highest level (university) was 0.57 (95% CI 0.55; 0.58) in men and 0.84 (95% CI 0.81; 0.87) in women. Higher education was associated with reduced risk of mortality from lip, oral cavity, pharynx, oesophagus, stomach, colon and liver in both sexes. Higher education (university) was associated with decreased risk of lung cancer in men (MRR: 0.43, 95% CI 0.41; 0.46), but not in women (MRR: 1.00, 95% CI 0.92; 1.10). Highly educated women had a reduced risk of mortality from cervical cancer than lower educated women (MRR: 0.39, 95% CI 0.27; 0.56), but they had a similar risk for breast cancer (MRR: 1.01, 95% CI 0.94; 1.09). Education is inversely associated with total cancer mortality, and the association was stronger in men. Different patterns and trends in tobacco smoking in men and women account for at least most of the gender differences.

  6. Multiple Replica Repulsion Technique for Efficient Conformational Sampling of Biological Systems

    PubMed Central

    Malevanets, Anatoly; Wodak, Shoshana J.

    2011-01-01

    Here, we propose a technique for sampling complex molecular systems with many degrees of freedom. The technique, termed “multiple replica repulsion” (MRR), does not suffer from poor scaling with the number of degrees of freedom associated with common replica exchange procedures and does not require sampling at high temperatures. The algorithm involves creation of multiple copies (replicas) of the system, which interact with one another through a repulsive potential that can be applied to the system as a whole or to portions of it. The proposed scheme prevents oversampling of the most populated states and provides accurate descriptions of conformational perturbations typically associated with sampling ground-state energy wells. The performance of MRR is illustrated for three systems of increasing complexity. A two-dimensional toy potential surface is used to probe the sampling efficiency as a function of key parameters of the procedure. MRR simulations of the Met-enkephalin pentapeptide, and the 76-residue protein ubiquitin, performed in presence of explicit water molecules and totaling 32 ns each, investigate the ability of MRR to characterize the conformational landscape of the peptide, and the protein native basin, respectively. Results obtained for the enkephalin peptide reflect more closely the extensive conformational flexibility of this peptide than previously reported simulations. Those obtained for ubiquitin show that conformational ensembles sampled by MRR largely encompass structural fluctuations relevant to biological recognition, which occur on the microsecond timescale, or are observed in crystal structures of ubiquitin complexes with other proteins. MRR thus emerges as a very promising simple and versatile technique for modeling the structural plasticity of complex biological systems. PMID:21843487

  7. Millimeter-Wave Spectroscopy for Analytical Chemistry: Thermal Evolution of Low Volatility Impurities and Detection with a Fourier Transform Molecular Rotational Resonance Spectrometer (tev Ft-Mrr

    NASA Astrophysics Data System (ADS)

    Harris, Brent; Fields, Shelby S.; Neill, Justin L.; Pulliam, Robin; Muckle, Matt; Pate, Brooks

    2016-06-01

    Recent advances in Fourier transform millimeter-wave spectroscopy techniques have renewed the application reach of molecular rotational spectroscopy for analytical chemistry. We present a sampling method for sub ppm analysis of low volatility impurities by thermal evolution from solid powders using a millimeter-wave Fourier transform molecular rotational resonance (FT-MRR) spectrometer for detection. This application of FT-MRR is relevant to the manufacturing of safe oral pharmaceuticals. Low volatility impurities can be challenging to detect at 1 ppm levels with chromatographic techniques. One such example of a potentially mutagenic impurity is acetamide (v.p. 1 Torr at 40 C, m.p. 80 C). We measured the pure reference spectrum of acetamide by flowing the sublimated vapor pressure of acetamide crystals through the FT-MRR spectrometer. The spectrometer lower detection level (LDL) for a broadband (> 20 GHz, 10 min.) spectrum is 300 nTorr, 30 pmol, or 2 ng. For a 50 mg powder, perfect sample transfer efficiency can yield a w/w % detection limit of 35 ppb. We extended the sampling method for the acetamide reference measurement to an acetaminophen sample spiked with 5000 ppm acetamide in order to test the sample transfer efficiency when liberated from an pharmaceutical powder. A spectral reference matching algorithm detected the presence of several impurities including acetaldehyde, acetic acid, and acetonitrile that evolved at the melting point of acetaminophen, demonstrating the capability of FT-MRR for identification without a routine chemical standard. The method detection limit (MDL) without further development is less than 10 ppm w/w %. Resolved FT-MRR mixture spectra will be presented with a description of sampling methods.

  8. Vertical Variability of Rain Drop Size Distribution from Micro Rain Radar Measurements during IFloodS

    NASA Astrophysics Data System (ADS)

    Adirosi, Elisa; Tokay, Ali; Roberto, Nicoletta; Gorgucci, Eugenio; Montopoli, Mario; Baldini, Luca

    2017-04-01

    Ground based weather radars are highly used to generate rainfall products for meteorological and hydrological applications. However, weather radar quantitative rainfall estimation is obtained at a certain altitude that depends mainly on the radar elevation angle and on the distance from the radar. Therefore, depending on the vertical variability of rainfall, a time-height ambiguity between radar measurement and rainfall at the ground can affect the rainfall products. The vertically pointing radars (such as the Micro Rain Radar, MRR) are great tool to investigate the vertical variability of rainfall and its characteristics and ultimately, to fill the gap between the ground level and the first available radar elevation. Furthermore, the knowledge of rain Drop Size Distribution (DSD) variability is linked to the well-known problem of the non-uniform beam filling that is one of the main uncertainties of Global Precipitation Measurement (GPM) mission Dual frequency Precipitation Radar (DPR). During GPM Ground Validation Iowa Flood Studies (IFloodS) field experiment, data collected with 2D video disdrometers (2DVD), Autonomous OTT Parsivel2 Units (APU), and MRR profilers at different sites were available. In three different sites co-located APU, 2DVD and MRR are available and covered by the S-band Dual Polarimetric Doppler radar (NPOL). The first elevation height of the radar beam varies, among the three sites, between 70 m and 1100 m. The IFloodS set-up has been used to compare disdrometers, MRR and NPOL data and to evaluate the uncertainties of those measurements. First, the performance of disdrometers and MRR in determining different rainfall parameters at ground has been evaluated and then the MRR based parameters have been compared with the ones obtained from NPOL data at the lowest elevations. Furthermore, the vertical variability of DSD and integral rainfall parameters within the MRR bins (from ground to 1085 m each 35 m) has been investigated in order to provide some insight on the variability of the rainfall microphysical characteristics within about 1 km above the ground.

  9. The Membrane-Bound NAC Transcription Factor ANAC013 Functions in Mitochondrial Retrograde Regulation of the Oxidative Stress Response in Arabidopsis[C][W

    PubMed Central

    De Clercq, Inge; Vermeirssen, Vanessa; Van Aken, Olivier; Vandepoele, Klaas; Murcha, Monika W.; Law, Simon R.; Inzé, Annelies; Ng, Sophia; Ivanova, Aneta; Rombaut, Debbie; van de Cotte, Brigitte; Jaspers, Pinja; Van de Peer, Yves; Kangasjärvi, Jaakko; Whelan, James; Van Breusegem, Frank

    2013-01-01

    Upon disturbance of their function by stress, mitochondria can signal to the nucleus to steer the expression of responsive genes. This mitochondria-to-nucleus communication is often referred to as mitochondrial retrograde regulation (MRR). Although reactive oxygen species and calcium are likely candidate signaling molecules for MRR, the protein signaling components in plants remain largely unknown. Through meta-analysis of transcriptome data, we detected a set of genes that are common and robust targets of MRR and used them as a bait to identify its transcriptional regulators. In the upstream regions of these mitochondrial dysfunction stimulon (MDS) genes, we found a cis-regulatory element, the mitochondrial dysfunction motif (MDM), which is necessary and sufficient for gene expression under various mitochondrial perturbation conditions. Yeast one-hybrid analysis and electrophoretic mobility shift assays revealed that the transmembrane domain–containing NO APICAL MERISTEM/ARABIDOPSIS TRANSCRIPTION ACTIVATION FACTOR/CUP-SHAPED COTYLEDON transcription factors (ANAC013, ANAC016, ANAC017, ANAC053, and ANAC078) bound to the MDM cis-regulatory element. We demonstrate that ANAC013 mediates MRR-induced expression of the MDS genes by direct interaction with the MDM cis-regulatory element and triggers increased oxidative stress tolerance. In conclusion, we characterized ANAC013 as a regulator of MRR upon stress in Arabidopsis thaliana. PMID:24045019

  10. 45 Mbps cat's eye modulating retro-reflector link over 7 Km

    NASA Astrophysics Data System (ADS)

    Rabinovich, W. S.; Mahon, R.; Goetz, P. G.; Swingen, L.; Murphy, J.; Ferraro, M.; Burris, R.; Suite, M.; Moore, C. I.; Gilbreath, G. C.; Binari, S.

    2006-09-01

    Modulating retro-reflectors (MRR) allow free space optical links with no need for pointing, tracking or a laser on one end of the link. They work by coupling a passive optical retro-reflector with an optical modulator. The most common kind of MRR uses a corner cube retro-reflector. These devices must have a modulator whose active area is as large as the area of the corner cube. This limits the ability to close longer range high speed links because the large aperture need to return sufficient light implies a large modulator capacitance. To overcome this limitation we developed the concept of a cat's eye MRR. Cat's eye MRRs place the modulator in the focal plane of a lens system designed to passively retro-reflect light. Because the light focuses onto the modulator, a small, low capacitance, modulator can be used with a large optical aperture. However, the position of the focal spot varies with the angle of incidence so an array of modulators must be placed in the focal plane, In addition, to avoid having to drive all the modulator pixels, an angle of arrival sensor must be used. We discuss several cat's eye MRR systems with near diffraction limited performance and bandwidths of 45 Mbps. We also discuss a link to a cat's eye MRR over a 7 Km range.

  11. Multi Response Optimization of Process Parameters Using Grey Relational Analysis for Turning of Al-6061

    NASA Astrophysics Data System (ADS)

    Deepak, Doreswamy; Beedu, Rajendra

    2017-08-01

    Al-6061 is one among the most useful material used in manufacturing of products. The major qualities of Aluminium are reasonably good strength, corrosion resistance and thermal conductivity. These qualities have made it a suitable material for various applications. While manufacturing these products, companies strive for reducing the production cost by increasing Material Removal Rate (MRR). Meanwhile, the quality of surface need to be ensured at an acceptable value. This paper aims at bringing a compromise between high MRR and low surface roughness requirement by applying Grey Relational Analysis (GRA). This article presents the selection of controllable parameters like longitudinal feed, cutting speed and depth of cut to arrive at optimum values of MRR and surface roughness (Ra). The process parameters for experiments were selected based on Taguchi’s L9 array with two replications. Grey relation analysis being most suited method for multi response optimization, the same is adopted for the optimization. The result shows that feed rate is the most significant factor that influences MRR and Surface finish.

  12. The effect of different water immersion temperatures on post-exercise parasympathetic reactivation.

    PubMed

    de Oliveira Ottone, Vinícius; de Castro Magalhães, Flávio; de Paula, Fabrício; Avelar, Núbia Carelli Pereira; Aguiar, Paula Fernandes; da Matta Sampaio, Pâmela Fiche; Duarte, Tamiris Campos; Costa, Karine Beatriz; Araújo, Tatiane Líliam; Coimbra, Cândido Celso; Nakamura, Fábio Yuzo; Amorim, Fabiano Trigueiro; Rocha-Vieira, Etel

    2014-01-01

    We evaluated the effect of different water immersion (WI) temperatures on post-exercise cardiac parasympathetic reactivation. Eight young, physically active men participated in four experimental conditions composed of resting (REST), exercise session (resistance and endurance exercises), post-exercise recovery strategies, including 15 min of WI at 15°C (CWI), 28°C (TWI), 38°C (HWI) or control (CTRL, seated at room temperature), followed by passive resting. The following indices were assessed before and during WI, 30 min post-WI and 4 hours post-exercise: mean R-R (mR-R), the natural logarithm (ln) of the square root of the mean of the sum of the squares of differences between adjacent normal R-R (ln rMSSD) and the ln of instantaneous beat-to-beat variability (ln SD1). The results showed that during WI mRR was reduced for CTRL, TWI and HWI versus REST, and ln rMSSD and ln SD1 were reduced for TWI and HWI versus REST. During post-WI, mRR, ln rMSSD and ln SD1 were reduced for HWI versus REST, and mRR values for CWI were higher versus CTRL. Four hours post exercise, mRR was reduced for HWI versus REST, although no difference was observed among conditions. We conclude that CWI accelerates, while HWI blunts post-exercise parasympathetic reactivation, but these recovery strategies are short-lasting and not evident 4 hours after the exercise session.

  13. The Effect of Different Water Immersion Temperatures on Post-Exercise Parasympathetic Reactivation

    PubMed Central

    de Oliveira Ottone, Vinícius; de Castro Magalhães, Flávio; de Paula, Fabrício; Avelar, Núbia Carelli Pereira; Aguiar, Paula Fernandes; da Matta Sampaio, Pâmela Fiche; Duarte, Tamiris Campos; Costa, Karine Beatriz; Araújo, Tatiane Líliam; Coimbra, Cândido Celso; Nakamura, Fábio Yuzo; Amorim, Fabiano Trigueiro; Rocha-Vieira, Etel

    2014-01-01

    Purpose We evaluated the effect of different water immersion (WI) temperatures on post-exercise cardiac parasympathetic reactivation. Methods Eight young, physically active men participated in four experimental conditions composed of resting (REST), exercise session (resistance and endurance exercises), post-exercise recovery strategies, including 15 min of WI at 15°C (CWI), 28°C (TWI), 38°C (HWI) or control (CTRL, seated at room temperature), followed by passive resting. The following indices were assessed before and during WI, 30 min post-WI and 4 hours post-exercise: mean R-R (mR-R), the natural logarithm (ln) of the square root of the mean of the sum of the squares of differences between adjacent normal R–R (ln rMSSD) and the ln of instantaneous beat-to-beat variability (ln SD1). Results The results showed that during WI mRR was reduced for CTRL, TWI and HWI versus REST, and ln rMSSD and ln SD1 were reduced for TWI and HWI versus REST. During post-WI, mRR, ln rMSSD and ln SD1 were reduced for HWI versus REST, and mRR values for CWI were higher versus CTRL. Four hours post exercise, mRR was reduced for HWI versus REST, although no difference was observed among conditions. Conclusions We conclude that CWI accelerates, while HWI blunts post-exercise parasympathetic reactivation, but these recovery strategies are short-lasting and not evident 4 hours after the exercise session. PMID:25437181

  14. Report of Apollo 204 Review Board to the Administrator, National Aeronautics and Space Administration . Appendix F ; Schedule of Physical Evidence

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Immediately following the Apollo 204 accident of January 27, 1961. all associated equipment and material were impounded. Release of this equipment and material for normal use was under the close control of the Apollo 204 Review Board. Apollo Review Board Administrative Procedure No. 11, February 11, 1961, established the Apollo 204 Review Board Material Release Record (MRR). This MRR was the official form used to release material from full impoundment and was valid only after being approved by the Board and signed by a Member. The form was used as the authority to place any impounded item into one of the three Categories defined in Administrative Procedure No. 11. This appendix contains all of the authorized MRR's. Each item submitted on an MRR was given a control number; a description, including the part number and serial number; the relevance and location to the accident; any constraints before release; and the control category. The categories placed on the equipment were as follows: Category A - Items which may have a significant influence or bearing on the results or findings of the Apollo 204 Review Board; Category B - All material other than Category A which is considered relevant to the Apollo 204 Review Board investigation; Category C - Material released from Board jurisdiction. Several classes of equipment were released by special Board action prior to the establishment of the MRR system. The operating procedure for release of these classes is Enclosure F-l to this appendix.

  15. Wave-optics simulation of the double-pass beam propagation in modulating retro-reflector FSO systems using a corner cube reflector.

    PubMed

    Yang, Guowei; You, Shengzui; Bi, Meihua; Fan, Bing; Lu, Yang; Zhou, Xuefang; Li, Jing; Geng, Hujun; Wang, Tianshu

    2017-09-10

    Free-space optical (FSO) communication utilizing a modulating retro-reflector (MRR) is an innovative way to convey information between the traditional optical transceiver and the semi-passive MRR unit that reflects optical signals. The reflected signals experience turbulence-induced fading in the double-pass channel, which is very different from that in the traditional single-pass FSO channel. In this paper, we consider the corner cube reflector (CCR) as the retro-reflective device in the MRR. A general geometrical model of the CCR is established based on the ray tracing method to describe the ray trajectory inside the CCR. This ray tracing model could treat the general case that the optical beam is obliquely incident on the hypotenuse surface of the CCR with the dihedral angle error and surface nonflatness. Then, we integrate this general CCR model into the wave-optics (WO) simulation to construct the double-pass beam propagation simulation. This double-pass simulation contains the forward propagation from the transceiver to the MRR through the atmosphere, the retro-reflection of the CCR, and the backward propagation from the MRR to the transceiver, which can be realized by a single-pass WO simulation, the ray tracing CCR model, and another single-pass WO simulation, respectively. To verify the proposed CCR model and double-pass WO simulation, the effective reflection area, the incremental phase, and the reflected beam spot on the transceiver plane of the CCR are analyzed, and the numerical results are in agreement with the previously published results. Finally, we use the double-pass WO simulation to investigate the double-pass channel in the MRR FSO systems. The histograms of the turbulence-induced fading in the forward and backward channels are obtained from the simulation data and are fitted by gamma-gamma (ΓΓ) distributions. As the two opposite channels are highly correlated, we model the double-pass channel fading by the product of two correlated ΓΓ random variables (RVs).

  16. South Carolina Commission on Higher Education Mission Resource Requirement, FY 2005-2006

    ERIC Educational Resources Information Center

    South Carolina Commission on Higher Education, 2005

    2005-01-01

    The Mission Resource Requirement (MRR) represents the level of funding necessary for an institution given its mission, size, and complexity of programs, based on regional and national norms, and the amount of the previous year's appropriation. This document is the MRR for the South Carolina Commission on Higher Education for Fiscal Year 2005-2006.…

  17. All-cause mortality in adults with and without type 2 diabetes: findings from the national health monitoring in Germany

    PubMed Central

    Brinks, Ralph; Baumert, Jens; Paprott, Rebecca; Du, Yong; Heidemann, Christin; Scheidt-Nave, Christa

    2017-01-01

    Objective To estimate age-specific and sex-specific all-cause mortality among adults with and without type 2 diabetes (T2D) in Germany. Research design and methods The German National Health Interview and Examination Survey 1998 (GNHIES98) included a mortality follow-up (median follow-up time 12.0 years) of its nationwide sample representative of the population aged 18–79 years. After exclusion of participants with type 1 diabetes, age- and sex-stratified mortality rates (MR) were calculated for 330 GNHIES98 participants with diagnosed T2D (self-reported diagnosis or antidiabetic medication), 245 with undiagnosed T2D (no diagnosed T2D, glycated hemoglobin A1c ≥6.5% (≥48 mmol/mol)), and 5975 without T2D. Mortality rate ratios (MRR) comparing MR of persons with and without T2D were estimated. Age-/sex-standardized MR and MRR were calculated including persons aged 45 years or older. MRR were used to estimate the number of years of life lost (YLL) due to diagnosed diabetes in 2010. Results Over 75 994 person-years, 73 persons with undiagnosed T2D, 103 with diagnosed T2D, and 425 persons without T2D died. MRR were significantly higher in younger age groups, except for analyses limited to women or diagnosed T2D. Age- and sex-standardized MRR (95% CI) among persons aged 45 years or older were 1.96 (1.41 to 2.71) for undiagnosed, 1.68 (1.26 to 2.23) for diagnosed, and 1.82 (1.45 to 2.28) for total (undiagnosed or diagnosed) T2D. Sex-stratified analysis revealed similar age-standardized MRR for undiagnosed (1.56 (0.79 to 3.06)) and diagnosed T2D (1.56 (1.03 to 2.37)) among women, and a higher age-standardized MRR for undiagnosed (2.06 (1.43 to 2.97)) than diagnosed T2D (1.70 (1.10 to 2.63)) among men. YLL due to diagnosed diabetes in Germany in 2010 were 164 600 (35 000 to 279 300) among women and 169 900 (28 300 to 328 300) among men. Conclusions In Germany, age- and sex-standardized all-cause mortality is almost twice as high for adults with T2D as for adults without T2D. The T2D-associated excess risk of mortality appears to be most pronounced in younger adults and among men unaware of their T2D. PMID:29435349

  18. The impact of preadmission oral bisphosphonate use on 30-day mortality following stroke: a population-based cohort study of 100,043 patients

    PubMed Central

    Christensen, Diana Hedevang; Horváth-Puhó, Erzsébet; Schmidt, Morten; Christiansen, Christian Fynbo; Pedersen, Lars; Langdahl, Bente Lomholt; Thomsen, Reimar Wernich

    2015-01-01

    Purpose Bisphosphonate use has been associated with increased risk of fatal stroke. We examined the association between preadmission use of oral bisphosphonates and 30-day mortality following hospitalization for stroke. Patients and methods We conducted a nationwide population-based cohort study using medical databases and identified all patients in Denmark with a first-time hospitalization for stroke between 1 July 2004 and 31 December 2012 (N=100,043). Cox regression was used to compute adjusted hazard ratios as a measure of 30-day mortality rate ratios (MRRs) associated with bisphosphonate current use (prescription filled within 90 days prior to the stroke) or recent use (prescription filled in the 90–180 days prior to the stroke). Current use was further classified as new or long-term use. Results We found 51,982 patients with acute ischemic stroke (AIS), 11,779 with intracerebral hemorrhage (ICH), 4,528 with subarachnoid hemorrhage (SAH), and 31,754 with unspecified stroke. Absolute 30-day mortality risks were increased among current vs nonusers of bisphosphonates for AIS (11.9% vs 8.5%), ICH (43.2% vs 34.5%), SAH (40.3% vs 23.2%), and unspecified strokes (18.8% vs 14.0%). However, in adjusted analyses, current bisphosphonate use did not increase 30-day mortality from AIS (MRR, 0.87; 95% confidence interval [CI]: 0.75, 1.01); ICH (MRR, 1.05; 95% CI: 0.90, 1.23); SAH (MRR, 1.15; 95% CI: 0.83, 1.61); or unspecified stroke (MRR, 0.94; 95% CI: 0.81, 1.09). Likewise, no association with mortality was found for recent use. Adjusted analyses by type of bisphosphonate showed increased mortality following stroke among new users of etidronate (MRR, 1.40; 95% CI: 1.01, 1.93) and reduced mortality after AIS among current users of alendronate (MRR, 0.87; 95% CI: 0.74, 1.02). Conclusion We found no overall evidence that preadmission bisphosphonate use increases 30-day mortality following stroke. PMID:26346502

  19. Performance of colloidal silica and ceria based slurries on CMP of Si-face 6H-SiC substrates

    NASA Astrophysics Data System (ADS)

    Chen, Guomei; Ni, Zifeng; Xu, Laijun; Li, Qingzhong; Zhao, Yongwu

    2015-12-01

    Colloidal silica and ceria based slurries, both using KMnO4 as an oxidizer, for chemical mechanical polishing (CMP) of Si-face (0 0 0 1) 6H-SiC substrate, were investigated to obtain higher material removal rate (MRR) and ultra-smooth surface. The results indicate that there was a significant difference in the CMP performance of 6H-SiC between silica and ceria based slurries. For the ceria based slurries, a higher MRR was obtained, especially in strong acid KMnO4 environment, and the maximum MRR (1089 nm/h) and a smoother surface with an average roughness Ra of 0.11 nm was achieved using slurries containing 2 wt% colloidal ceria, 0.05 M KMnO4 at pH 2. In contrast, due to the attraction between negative charged silica particles and positive charged SiC surface below pH 5, the maximum MRR of silica based slurry was only 185 nm/h with surface roughness Ra of 0.254 nm using slurries containing 6 wt% colloidal silica, 0.05 M KMnO4 at pH 6. The polishing mechanism was discussed based on the zeta potential measurements of the abrasives and the X-ray photoelectron spectroscopy (XPS) analysis of the polished SiC surfaces.

  20. Monitoring All Weather Precipitation Using PIP and MRR

    NASA Astrophysics Data System (ADS)

    Bliven, Francis; Petersen, Walter; Kulie, Mark; Pettersen, Claire; Wolff, David; Dutter, Michael

    2015-04-01

    The objective of this study is to demonstrate the science benefit of monitoring all weather precipitation for the Global Precipitation Measurement (GPM) Mission Ground Validation Program using a combination of two instruments: the Precipitation Imaging Package (PIP) and a Microwave Rain Radar-II (MRR). The PIP is a new ground based precipitation imaging instrument that uses a high speed camera and advanced processing software to image individual hydrometeors, measure hydrometeor size distributions, track individual hydrometeors and compute fall velocities. PIP hydrometeor data are also processed using algorithms to compute precipitation rates in one-minute time increments, and to discriminate liquid, mixed and frozen (e.g., snow) precipitation. The MRR, a vertically-pointing 24 GHz radar, is well documented in the literature and monitors hydrometeor vertical profile characteristics such as Doppler fall-speed spectra, radar reflectivity, size distribution and precipitation rate. Of interest to GPM direct and physical ground validation are collections of robust, satellite overpass-coincident, long-duration datasets consisting of observations of the aforementioned hydrometeor characteristics for falling snow and mixes of falling-snow and rain, as there are relatively few instruments that provide continuous observations of coincident hydrometeor image, size, and fall velocity in cold regions due to harsh environmental conditions. During extended periods of 2013 and 2014, concurrent PIP and MRR data sets were obtained at the National Weather Service station in Marquette, Michigan (2014), and at the NASA Wallops Flight Facility in Wallops Island, Virginia (2013,14). Herein we present examples of those data sets for a variety of weather conditions (rain, snow, frontal passages, lake effect snow events etc.). The results demonstrate 1) that the PIP and MRR are well-suited to long term operation in cold regions; 2) PIP and MRR data products are useful for characterizing a wide variety of precipitation types and conditions; 3) systematic variability in bulk snow characteristics such as fall speed and size distributions can be observed between event types, but also within individual event types (e.g., within a given synoptic or lake effect storm). The observed behavior suggests that added information on environmental or cloud parameters may be necessary to further define snowfall types/regimes or to estimate snow water equivalent rates using satellite or ground-based active or passive remote sensing tools.

  1. Multiresponse Optimization of Process Parameters in Turning of GFRP Using TOPSIS Method

    PubMed Central

    Parida, Arun Kumar; Routara, Bharat Chandra

    2014-01-01

    Taguchi's design of experiment is utilized to optimize the process parameters in turning operation with dry environment. Three parameters, cutting speed (v), feed (f), and depth of cut (d), with three different levels are taken for the responses like material removal rate (MRR) and surface roughness (R a). The machining is conducted with Taguchi L9 orthogonal array, and based on the S/N analysis, the optimal process parameters for surface roughness and MRR are calculated separately. Considering the larger-the-better approach, optimal process parameters for material removal rate are cutting speed at level 3, feed at level 2, and depth of cut at level 3, that is, v 3-f 2-d 3. Similarly for surface roughness, considering smaller-the-better approach, the optimal process parameters are cutting speed at level 1, feed at level 1, and depth of cut at level 3, that is, v 1-f 1-d 3. Results of the main effects plot indicate that depth of cut is the most influencing parameter for MRR but cutting speed is the most influencing parameter for surface roughness and feed is found to be the least influencing parameter for both the responses. The confirmation test is conducted for both MRR and surface roughness separately. Finally, an attempt has been made to optimize the multiresponses using technique for order preference by similarity to ideal solution (TOPSIS) with Taguchi approach. PMID:27437503

  2. Research Registries: A Tool to Advance Understanding of Rare Neuro-Ophthalmic Diseases.

    PubMed

    Blankshain, Kimberly D; Moss, Heather E

    2016-09-01

    Medical research registries (MRR) are organized systems used to collect, store, and analyze patient information. They are important tools for medical research with particular application to the study of rare diseases, including those seen in neuro-ophthalmic practice. Evidence for this review was gathered from the writers' experiences creating a comprehensive neuro-ophthalmology registry and review of the literature. MRR are typically observational and prospective databases of de-identified patient information. The structure is flexible and can accommodate a focus on specific diseases or treatments, surveillance of patient populations, physician quality improvement, or recruitment for future studies. They are particularly useful for the study of rare diseases. They can be integrated into the hierarchy of medical research at many levels provided their construction is well organized and they have several key characteristics including an easily manipulated database, comprehensive information on carefully selected patients, and comply with human subjects regulations. MRR pertinent to neuro-ophthalmology include the University of Illinois at Chicago neuro-ophthalmology registry, Susac Syndrome Registry, Intracranial Hypertension Registry, and larger-scale patient outcome registries being developed by professional societies. MRR have a variety of forms and applications. With careful planning and clear goals, they are flexible and powerful research tools that can support multiple different study designs, and this can provide the potential to advance understanding and care of neuro-ophthalmic diseases.

  3. Dispersal of Male Aedes aegypti in a Coastal Village in Southern Mexico

    PubMed Central

    Valerio, Laura; Facchinelli, Luca; Ramsey, Janine M.; Scott, Thomas W.

    2012-01-01

    Most Aedes aegypti dispersal studies have focused on females because of their central role in dengue virus transmission. Only a few mark-release-recapture (MRR) studies provided insights into male Ae. aegypti dispersal. To fill this knowledge gap, we conducted five male Ae. aegypti MRR experiments in a coastal village in southern Mexico. Small and large male cohorts were marked with fluorescent dusts, released outside buildings, and recaptures were carried out by using backpack aspirators. Recapture rates ranged between 0.35% and 6.55% and median distance traveled was 12–166 meters. A statistically significant difference in median distance traveled with large males dispersing farther than small ones was detected only in one experiment (MRR5: U = 3.5, P < 0.01). Male dispersal data will be useful for constructing and estimating parameter values and validating models that will be used to plan the most effective release strategies for genetically modified male Ae. aegypti. PMID:22492152

  4. Optical micro-cavities on silicon

    NASA Astrophysics Data System (ADS)

    Dai, Daoxin; Liu, Erhu; Tan, Ying

    2018-01-01

    Silicon-based optical microcavities are very popular for many applications because of the ultra-compact footprint, easy scalability, and functional versatility. In this paper we give a discussion about the challenges of the optical microcavities on silicon and also give a review of our recent work, including the following parts. First, a near-"perfect" high-order MRR optical filter with a box-like filtering response is realized by introducing bent directional couplers to have sufficient coupling between the access waveguide and the microrings. Second, an efficient thermally-tunable MRR-based optical filter with graphene transparent nano-heater is realized by introducing transparent graphene nanoheaters. Thirdly, a polarization-selective microring-based optical filter is realized to work with resonances for only one of TE and TM polarizations for the first time. Finally, a on-chip reconfigurable optical add-drop multiplexer for hybrid mode- /wavelength-division-multiplexing systems is realized for the first time by monolithically integrating a mode demultiplexer, four MRR optical switches, and a mode multiplexer.

  5. Spatial-temporal variability of precipitation in Mountainous Regions in the Southern Appalachians

    NASA Astrophysics Data System (ADS)

    Prat, O. P.; Barros, A. P.

    2009-09-01

    The purpose of this work is to investigate the mechanisms of mountainous precipitation and specifically to quantify the influence of the topography on the modification of microphysical and dynamical processes of large weather systems or on the onset of localized convective storms. Three measurement campaigns involving the deployment of one (July-August 2008) or two (October-November 2008, and June-July 2009) Micro Rain Radars (MMR) were conducted in the Great Smoky Mountains National Park (GSMNP) in the Southern Appalachians, with the goal to provide microphysical observations. Here we focus on the characterization of the diurnal cycle of rainfall and the yearly repartition of precipitation both from MRR records and from more than 30 rain gauges deployed from mid- to high-elevation along exposed ridges in the vicinity of the MRR deployment sites. A particular attention is paid to the quantification of space-time patterns of orographic enhancements between valley and ridge locations for the MRR deployment sites. The second aspect of this work, concerns a comparison of raingauge and vertically pointing radars (MRR) records with TRMM 2A25 precipitation products. A long term (from 6 months to more than two years and depending on the rain gauge installation) systematic statistical analysis is performed in order to quantify differences between ground based and remotely sensed observations for precipitation events at the time of satellite overpass. The presentation will provide a synthesis of data analysis and sensor intercomparison.

  6. The wavefront compensation of free space optics utilizing micro corner-cube-reflector arrays

    NASA Astrophysics Data System (ADS)

    You, Shengzui; Yang, Guowei; Li, Changying; Bi, Meihua; Fan, Bing

    2018-01-01

    The wavefront compensation effect of micro corner-cube-reflector arrays (MCCRAs) in modulating retroreflector (MRR) free-space optical (FSO) link is investigated theoretically and experimentally. Triangular aperture of MCCRAs has been optically characterized and studied in an indoor atmospheric turbulence channel. The use of the MCCRAs instead of a single corner-cube reflector (CCR) as the reflective device is found to improve dramatically the quality of the reflected beam spot. We draw a conclusion that the MCCRAs can in principle yield a powerful wavefront compensation in MRR FSO communication links.

  7. Modelling and multi objective optimization of WEDM of commercially Monel super alloy using evolutionary algorithms

    NASA Astrophysics Data System (ADS)

    Varun, Sajja; Reddy, Kalakada Bhargav Bal; Vardhan Reddy, R. R. Vishnu

    2016-09-01

    In this research work, development of a multi response optimization technique has been undertaken, using traditional desirability analysis and non-traditional particle swarm optimization techniques (for different customer's priorities) in wire electrical discharge machining (WEDM). Monel 400 has been selected as work material for experimentation. The effect of key process parameters such as pulse on time (TON), pulse off time (TOFF), peak current (IP), wire feed (WF) were on material removal rate (MRR) and surface roughness(SR) in WEDM operation were investigated. Further, the responses such as MRR and SR were modelled empirically through regression analysis. The developed models can be used by the machinists to predict the MRR and SR over a wide range of input parameters. The optimization of multiple responses has been done for satisfying the priorities of multiple users by using Taguchi-desirability function method and particle swarm optimization technique. The analysis of variance (ANOVA) is also applied to investigate the effect of influential parameters. Finally, the confirmation experiments were conducted for the optimal set of machining parameters, and the betterment has been proved.

  8. Improvement of MRR and surface roughness during electrical discharge machining (EDM) using aluminum oxide powder mixed dielectric fluid

    NASA Astrophysics Data System (ADS)

    Khan, A. A.; Mohiuddin, A. K. M.; Latif, M. A. A.

    2018-01-01

    This paper discusses the effect of aluminium oxide (Al203) addition to dielectric fluid during electrical discharge machining (EDM). Aluminium oxide was added to the dielectric used in the EDM process to improve its performance when machining the stainless steel AISI 304, while copper was used as the electrode. Effect of the concentration of Al203 (0.3 mg/L) in dielectric fluid was compared with EDM without any addition of Al203. Surface quality of stainless steel and the material removal rate were investigated. Design of the experiment (DOE) was used for the experimental plan. Statistical analysis was done using ANOVA and then appropriate model was designated. The experimental results show that with dispersing of aluminium oxide in dielectric fluid surface roughness was improved while the material removal rate (MRR) was increased to some extent. These indicate the improvement of EDM performance using aluminium oxide in dielectric fluid. It was also found that with increase in pulse on time both MRR and surface roughness increase sharply.

  9. Quadriceps muscle strength and voluntary activation after polio.

    PubMed

    Beelen, Anita; Nollet, Frans; de Visser, Marianne; de Jong, Bareld A; Lankhorst, Gustaaf J; Sargeant, Anthony J

    2003-08-01

    Quadriceps strength, maximal anatomical cross-sectional area (CSA), maximal voluntary activation (MVA), and maximal relaxation rate (MRR) were studied in 48 subjects with a past history of polio, 26 with and 22 without postpoliomyelitis syndrome (PPS), and in 13 control subjects. It was also investigated whether, apart from CSA, MVA and MRR were determinants of muscle strength. Polio subjects had significantly less strength, CSA, and MRR in the more-affected quadriceps than control subjects. MVA was reduced in 18 polio subjects and normal in all controls. PPS subjects differed from non-PPS subjects only in that the MVA of the more-affected quadriceps was significantly lower. Both CSA and MVA were found to be associated with muscle strength. Quadriceps strength in polio subjects was dependent not only on muscle mass, but also on the ability to activate the muscles. Since impaired activation was more pronounced in PPS subjects, the new muscle weakness and functional decline in PPS may be due not only to a gradual loss of muscle fibers, but also to an increasing inability to activate the muscles.

  10. NASTRAN User’s Colloquium (12th), Held in Orlando, FLorida on May 7-11, 1984

    DTIC Science & Technology

    1984-08-01

    Tennessee Eastman Company) 10.K-FINITE ELEMENT PREDICTION OF ACOUSTIC SCATTERING AND RADIATION FROM SUBMERGED ELASTIC STRUCTURES ... ...... .192 by...MCB’Iee) 2 (MRC*Ivv+MRR*O+MRB’ ) (MRC*H(R+MRRIRR+MRBFIBR) (MRCO+MRRO+MRBIee) p + LL(MBC I vv+ MBR *O+MBB*O) (MBCHCR+ MBR *IRR+MBB*HBR) (MBC’O+ MBR *O+MBB*Iee)J I...for the reed would consist of the partition MRR only and would be devoid of MCR and MBR and so would their transposes; i.e., no mass coupling between

  11. Jim Crow and premature mortality among the US Black and White population, 1960-2009: an age-period-cohort analysis.

    PubMed

    Krieger, Nancy; Chen, Jarvis T; Coull, Brent A; Beckfield, Jason; Kiang, Mathew V; Waterman, Pamela D

    2014-07-01

    Scant research has analyzed the health impact of abolition of Jim Crow (ie, legal racial discrimination overturned by the US 1964 Civil Rights Act). We used hierarchical age-period-cohort models to analyze US national black and white premature mortality rates (death before 65 years of age) in 1960-2009. Within a context of declining US black and white premature mortality rates and a persistent 2-fold excess black risk of premature mortality in both the Jim Crow and non-Jim Crow states, analyses including random period, cohort, state, and county effects and fixed county income effects found that, within the black population, the largest Jim Crow-by-period interaction occurred in 1960-1964 (mortality rate ratio [MRR] = 1.15 [95% confidence interval = 1.09-1.22), yielding the largest overall period-specific Jim Crow effect MRR of 1.27, with no such interactions subsequently observed. Furthermore, the most elevated Jim Crow-by-cohort effects occurred for birth cohorts from 1901 through 1945 (MRR range = 1.05-1.11), translating to the largest overall cohort-specific Jim Crow effect MRRs for the 1921-1945 birth cohorts (MRR ~ 1.2), with no such interactions subsequently observed. No such interactions between Jim Crow and either period or cohort occurred among the white population. Together, the study results offer compelling evidence of the enduring impact of both Jim Crow and its abolition on premature mortality among the US black population, although insufficient to eliminate the persistent 2-fold black excess risk evident in both the Jim Crow and non-Jim Crow states from 1960 to 2009.

  12. Jim Crow and Premature Mortality Among the US Black and White Population, 1960–2009

    PubMed Central

    Krieger, Nancy; Chen, Jarvis T.; Coull, Brent A.; Beckfield, Jason; Kiang, Mathew V.; Waterman, Pamela D.

    2016-01-01

    Background Scant research has analyzed the health impact of abolition of Jim Crow (ie, legal racial discrimination overturned by the US 1964 Civil Rights Act). Methods We used hierarchical age–period–cohort models to analyze US national black and white premature mortality rates (death before 65 years of age) in 1960–2009. Results Within a context of declining US black and white premature mortality rates and a persistent 2-fold excess black risk of premature mortality in both the Jim Crow and non-Jim Crow states, analyses including random period, cohort, state, and county effects and fixed county income effects found that, within the black population, the largest Jim Crow-by-period interaction occurred in 1960–1964 (mortality rate ratio [MRR] = 1.15 [95% confidence interval = 1.09–1.22), yielding the largest overall period-specific Jim Crow effect MRR of 1.27, with no such interactions subsequently observed. Furthermore, the most elevated Jim Crow-by-cohort effects occurred for birth cohorts from 1901 through 1945 (MRR range = 1.05–1.11), translating to the largest overall cohort-specific Jim Crow effect MRRs for the 1921–1945 birth cohorts (MRR ~ 1.2), with no such interactions subsequently observed. No such interactions between Jim Crow and either period or cohort occurred among the white population. Conclusion Together, the study results offer compelling evidence of the enduring impact of both Jim Crow and its abolition on premature mortality among the US black population, although insufficient to eliminate the persistent 2-fold black excess risk evident in both the Jim Crow and non-Jim Crow states from 1960 to 2009. PMID:24825344

  13. Reduced All-cause Child Mortality After General Measles Vaccination Campaign in Rural Guinea-Bissau.

    PubMed

    Fisker, Ane B; Rodrigues, Amabelia; Martins, Cesario; Ravn, Henrik; Byberg, Stine; Thysen, Sanne; Storgaard, Line; Pedersen, Marie; Fernandes, Manuel; Benn, Christine S; Aaby, Peter

    2015-12-01

    Randomized trials have shown that measles vaccine (MV) prevents nonmeasles deaths. MV campaigns are conducted to eliminate measles infection. The overall mortality effect of MV campaigns has not been studied. Bandim Health Project (BHP) surveys children aged 0-4 years in rural Guinea-Bissau through a health and demographic surveillance system. A national MV campaign in 2006 targeted children aged 6 months to 15 years. In a Cox proportional hazards model with age as the underlying timescale, we compared mortality of children aged 6-59 months after the campaign with mortality in the same age group during the 2 previous years. Eight thousand one hundred fifty eight children aged 6-59 months were under BHP surveillance during the 2006 campaign and 7999 and 8108 during similar periods in 2004 and 2005. At least 90% of the eligible children received MV in the campaign. There were 161 nonaccident deaths in 12 months after the campaign compared with 203 and 206 deaths in the 2 previous years, the adjusted mortality rate ratio (aMRR) comparing all children in 2006 with all children in 2004 to 2005 being 0.80 (95% confidence interval: 0.66-0.96). Censoring deaths caused by measles infection, the aMRR was 0.83 (0.69-1.00). The mortality reduction was separately significant for girls [aMRR = 0.74 (0.56-0.97)] and for children who also had received routine MV [MRR = 0.59 (0.36-0.99)]. Mortality levels were stable during 2004 and 2005, but a significant drop occurred after the 2006 MV campaign and was not explained by the prevention of measles deaths. If MV campaigns reduce nonmeasles-related mortality, the policies for measles vaccination should take this into account.

  14. Does exposure to aircraft noise increase the mortality from cardiovascular disease in the population living in the vicinity of airports? Results of an ecological study in France.

    PubMed

    Evrard, Anne-Sophie; Bouaoun, Liacine; Champelovier, Patricia; Lambert, Jacques; Laumon, Bernard

    2015-01-01

    The impact of aircraft noise on health is of growing concern. We investigated the relationship between this exposure and mortality from cardiovascular disease, coronary heart disease, myocardial infarction, and stroke. We performed an ecological study on 161 communes (commune being the smallest administrative unit in France) close to the following three major French airports: Paris-Charles de Gaulle, Lyon Saint-Exupéry, and Toulouse-Blagnac. The mortality data were provided by the French Center on Medical Causes of Death for the period 2007-2010. Based on the data provided by the French Civil Aviation Authority, a weighted average exposure to aircraft noise (L den AEI) was computed at the commune level. A Poisson regression model with commune-specific random intercepts, adjusted for potential confounding factors including air pollution, was used to investigate the association between mortality rates and L den AEI. Positive associations were observed between L den AEI and mortality from cardiovascular disease [adjusted mortality rate ratio (MRR) per 10 dB(A) increase in L den AEI = 1.18; 95% confidence interval (CI): 1.11-1.25], coronary heart disease [MRR = 1.24 (1.12-1.36)], and myocardial infarction [MRR = 1.28 (1.11-1.46]. Stroke mortality was more weakly associated with L den AEI [MRR = 1.08 (0.97-1.21]. These significant associations were not attenuated after the adjustment for air pollution. The present ecological study supports the hypothesis of an association between aircraft noise exposure and mortality from cardiovascular disease, coronary heart disease, and myocardial infarction. However, the potential for ecological bias and the possibility that this association could be due to residual confounding cannot be excluded.

  15. Does exposure to aircraft noise increase the mortality from cardiovascular disease in the population living in the vicinity of airports? Results of an ecological study in France

    PubMed Central

    Evrard, Anne-Sophie; Bouaoun, Liacine; Champelovier, Patricia; Lambert, Jacques; Laumon, Bernard

    2015-01-01

    The impact of aircraft noise on health is of growing concern. We investigated the relationship between this exposure and mortality from cardiovascular disease, coronary heart disease, myocardial infarction, and stroke. We performed an ecological study on 161 communes (commune being the smallest administrative unit in France) close to the following three major French airports: Paris-Charles de Gaulle, Lyon Saint-Exupéry, and Toulouse-Blagnac. The mortality data were provided by the French Center on Medical Causes of Death for the period 2007-2010. Based on the data provided by the French Civil Aviation Authority, a weighted average exposure to aircraft noise (Lden AEI) was computed at the commune level. A Poisson regression model with commune-specific random intercepts, adjusted for potential confounding factors including air pollution, was used to investigate the association between mortality rates and Lden AEI. Positive associations were observed between Lden AEI and mortality from cardiovascular disease [adjusted mortality rate ratio (MRR) per 10 dB(A) increase in Lden AEI = 1.18; 95% confidence interval (CI): 1.11-1.25], coronary heart disease [MRR = 1.24 (1.12-1.36)], and myocardial infarction [MRR = 1.28 (1.11-1.46]. Stroke mortality was more weakly associated with Lden AEI [MRR = 1.08 (0.97-1.21]. These significant associations were not attenuated after the adjustment for air pollution. The present ecological study supports the hypothesis of an association between aircraft noise exposure and mortality from cardiovascular disease, coronary heart disease, and myocardial infarction. However, the potential for ecological bias and the possibility that this association could be due to residual confounding cannot be excluded. PMID:26356375

  16. Effects of pulse ON and OFF time and electrode types on the material removal rate and tool wear rate of the Ti-6Al-4V Alloy using EDM machining with reverse polarity

    NASA Astrophysics Data System (ADS)

    Praveen, L.; Geeta Krishna, P.; Venugopal, L.; Prasad, N. E. C.

    2018-03-01

    Electrical Discharge Machining (EDM) is an unconventional metal removal process that is extensively used for removing the difficult-to-machine metal such as Ti alloys, super alloys and metal matrix composites. This paper investigates the effects of pulse (ON/OFF) time on EDM machining characteristics of Ti-6Al-4V alloy using copper and graphite as electrodes in reverse polarity condition. Full factorial design method was used to design the experiments. Two variables (Pulse On and OFF) with three levels are considered. The output variables are the tool wear rate and the material removal rate. The important findings from the present work are: (1) the material removal rate (MRR) increases gradually with an increase of the Pulse ON time whereas the change is insignificant with an increase of the Pulse OFF time, (2) Between copper and graphite electrodes, the copper electrode is proved to be good in terms of MRR, (3) a combination of high pulse ON time and OFF time is desirable for high MRR rate in the Cu electrode whereas for the graphite electrode, a combination of high pulse ON time and low pulse OFF time is desirable for high MRR rate, (4) the tool wear rate (TWR) reduces with the Pulse On or OFF time, the rate of TWR is uniform for the graphite electrode in contrast to abrupt decrease from 25 to 50 μs (pulse ON time) in the copper electrode, (5) In order to keep the TWR as minimum possible, it is desirable to have a combination of high pulse ON time and OFF time for both the copper and the graphite electrode.

  17. All-Cause Mortality in Women With Severe Postpartum Psychiatric Disorders

    PubMed Central

    Johannsen, Benedicte Marie Winther; Larsen, Janne Tidselbak; Laursen, Thomas Munk; Bergink, Veerle; Meltzer-Brody, Samantha; Munk-Olsen, Trine

    2017-01-01

    Objective The postpartum period is associated with a high risk of psychiatric episodes. The authors studied mortality in women with first-onset severe psychiatric disorders following childbirth and compared their mortality rates with those in women from the background population including other female psychiatric patients (mothers and childless women). Method In a register-based cohort study with linked information from Danish population registers, the authors identified women with first psychiatric inpatient or outpatient contacts 0–3 months postpartum. The main outcome measure was mortality rate ratios (MRRs): deaths from natural causes (diseases and medical conditions) or unnatural causes (suicides, accidents, and homicides). The cohort included 1,545,857 women representing 68,473,423 person-years at risk. Results In total, 2,699 women had first-onset psychiatric disorders 0–3 months postpartum, and 96 of these died during follow-up. Women with postpartum psychiatric disorders had a higher MRR (3.74; 95% CI=3.06–4.57) than non-postpartum-onset mothers (MRR=2.73; 95% CI=2.67–2.79) when compared with mothers with no psychiatric history. However, childless women with psychiatric diagnoses had the highest MRR (6.15; 95% CI=5.94–6.38). Unnatural cause of death represented 40.6% of fatalities among women with postpartum psychiatric disorders, and within the first year after diagnosis, suicide risk was drastically increased (MRR=289.42; 95% CI=144.02–581.62) when compared with mothers with no psychiatric history. Conclusions Women with severe postpartum psychiatric disorders had increased MRRs compared with mothers without psychiatric diagnoses, and the first year after diagnosis represents a time of particularly high relative risk for suicide in this vulnerable group. PMID:26940804

  18. The Effect of Treatment Advances on the Mortality Results of Breast Cancer Screening Trials: A Microsimulation Model.

    PubMed

    Birnbaum, Jeanette; Gadi, Vijayakrishna K; Markowitz, Elan; Etzioni, Ruth

    2016-02-16

    Mammography trials, which are the primary sources of evidence for screening benefit, were conducted decades ago. Whether advances in systemic therapies have rendered previously observed benefits of screening less significant is unknown. To compare the outcomes of breast cancer screening trials had they been conducted using contemporary systemic treatments with outcomes of trials conducted with previously used treatments. Computer simulation model of 3 virtual screening trials with similar reductions in advanced-stage cancer cases but reflecting treatment patterns in 1975 (prechemotherapy era), 1999, or 2015 (treatment according to receptor status). Meta-analyses of screening and treatment trials; study of dissemination of primary systemic treatments; SEER (Surveillance, Epidemiology, and End Results) registry. U.S. women aged 50 to 74 years. 10 and 25 years. Population. Mammography, chemotherapy, tamoxifen, aromatase inhibitors, and trastuzumab. Breast cancer mortality rate ratio (MRR) and absolute risk reduction (ARR) obtained by the difference in cumulative breast cancer mortality between control and screening groups. At 10 years, screening in a 1975 trial yielded an MRR of 90% and an ARR of 5 deaths per 10,000 women. A 2015 screening trial yielded a 10-year MRR of 90% and an ARR of 3 deaths per 10,000 women. Greater reductions in advanced-stage disease yielded a greater screening effect, but MRRs remained similar across trials. However, ARRs were consistently lower under contemporary treatments. When contemporary treatments were available only for early-stage cases, the MRR was 88%. Disease models simplify reality and cannot capture all breast cancer subtypes. Advances in systemic therapies for breast cancer have not substantively reduced the relative benefits of screening but have likely reduced the absolute benefits because of their positive effect on breast cancer survival. University of Washington and National Cancer Institute.

  19. Spot breeding method to evaluate the determinism of magnetorheological finishing

    NASA Astrophysics Data System (ADS)

    Yang, Hang; He, Jianguo; Huang, Wen; Zhang, Yunfei

    2017-03-01

    The influences of immersion depth of magnetorheological finishing (MRF) on the shape and material removal rate (MRR) of removal function are theoretically investigated to establish the spot transition mechanism. Based on this mechanism, for the first time, the spot breeding method to predict the shape and removal rate of MRF spot is proposed. The UBK7 optical parts are polished to verify the proposed method on experimental installation PKC-1000Q2 developed by ourselves. The experimental results reveal that the predictions of shape and MRR with this method are precise. The proposed method provides a basis for analyzing the determinism of MRF due to geometry of the process.

  20. Non-specific effects of diphtheria-tetanus-pertussis and measles vaccinations? An analysis of surveillance data from Navrongo, Ghana.

    PubMed

    Welaga, Paul; Nielsen, Jens; Adjuik, Martin; Debpuur, Cornelius; Ross, David A; Ravn, Henrik; Benn, Christine S; Aaby, Peter

    2012-12-01

    Studies from low-income countries have suggested that routine vaccinations may have non-specific effects on child mortality; measles vaccine (MV) is associated with lower mortality and diphtheria-tetanus-pertussis (DTP) with relatively higher mortality. We used data from Navrongo, Ghana, to examine the impact of vaccinations on child mortality. Vaccination status was assessed at the initiation of a trial of vitamin A supplementation and after 12 and 24 months of follow-up. Within the placebo group, we compared the mortality over the first 4 months and the full 2 years of follow-up for different vaccination status groups with different likelihoods of additional vaccinations during follow-up. The frequency of additional vaccinations was assessed among children whose vaccination card was seen at 12 and 24 months of follow-up. Among children with a vaccination card, more than 75% received missing DTP or MV during the first 12 months of follow-up, whereas only 25% received these vaccines among children with no vaccination card at enrollment. Children without a card at enrollment had a significant threefold higher mortality over the 2-year follow-up period than those fully vaccinated. The small group of children with DTP3-4 but no MV at enrollment had lower mortality than children without a card and had the same mortality as fully vaccinated children. In contrast, children with 1-2 DTP doses but no MV had a higher mortality during the first 4 months than children without a card [MRR = 1.65 (0.95, 2.87)]; compared with the fully vaccinated children, they had significantly higher mortality after 4 months [MRR = 2.38 (1.07, 5.30)] and after 2 years [MRR = 2.41 (1.41, 4.15)]. Children with 0-2 DTP doses at enrollment had higher mortality after 4 months (MRR = 1.67 (0.82, 3.43) and after 2 years [MRR = 1.85 (1.16, 2.95)] than children who had all three doses of DTP at enrollment. As hypothesised, DTP vaccination was associated with higher child mortality than measles vaccination. To optimise vaccination policies, routine vaccinations need to be evaluated in randomised trials measuring the impact on survival. © 2012 Blackwell Publishing Ltd.

  1. Two-pole microring weight banks.

    PubMed

    Tait, Alexander N; Wu, Allie X; Ferreira de Lima, Thomas; Nahmias, Mitchell A; Shastri, Bhavin J; Prucnal, Paul R

    2018-05-15

    Weighted addition is an elemental multi-input to single-output operation that can be implemented with high-performance photonic devices. Microring (MRR) weight banks bring programmable weighted addition to silicon photonics. Prior work showed that their channel limits are affected by coherent inter-channel effects that occur uniquely in weight banks. We fabricate two-pole designs that exploit this inter-channel interference in a way that is robust to dynamic tuning and fabrication variation. Scaling analysis predicts a channel count improvement of 3.4-fold, which is substantially greater than predicted by incoherent analysis used in conventional MRR devices. Advances in weight bank design expand the potential of reconfigurable analog photonic networks and multivariate microwave photonics.

  2. Athermal synchronization of laser source with WDM filter in a silicon photonics platform

    PubMed Central

    Li, Nanxi; Purnawirman; Salih Magden, E.; Poulton, Christopher V.; Ruocco, Alfonso; Singh, Neetesh; Byrd, Matthew J.; Bradley, Jonathan D. B.; Leake, Gerald; Watts, Michael R.

    2017-01-01

    In an optical interconnect circuit, microring resonators (MRRs) are commonly used in wavelength division multiplexing systems. To make the MRR and laser synchronized, the resonance wavelength of the MRR needs to be thermally controlled, and the power consumption becomes significant with a high-channel count. Here, we demonstrate an athermally synchronized rare-earth-doped laser and MRR. The laser comprises a Si3N4 based cavity covered with erbium-doped Al2O3 to provide gain. The low thermo-optic coefficient of Al2O3 and Si3N4 and the comparable thermal shift of the effective index in the laser and microring cross-sections enable lasing and resonance wavelength synchronization over a wide range of temperatures. The power difference between matched and unmatched channels remains greater than 15 dB from 20 to 50 °C due to a synchronized wavelength shift of 0.02 nm/°C. The athermal synchronization approach reported here is not limited to microring filters but can be applied to any Si3N4 filter with integrated lasers using rare earth ion doped Al2O3 as a gain medium to achieve system-level temperature control free operation. PMID:28611487

  3. How have changes in air bag designs affected frontal crash mortality?

    PubMed

    Braver, Elisa R; Shardell, Michelle; Teoh, Eric R

    2010-07-01

    To determine whether front air bag changes have affected occupant protection, frontal crash mortality rates were compared among front outboard occupants in vehicles having certified-advanced air bags (latest generation of air bags) or sled-certified air bags with and without advanced features. Poisson marginal structural models were used to calculate standardized mortality rate ratios (MRRs) for front occupants per registered vehicle. Vehicle age-corrected mortality rates were lower for drivers of vehicles having sled-certified air bags with advanced features than for drivers having sled-certified air bags without advanced features (MRR = 0.88; 95% confidence interval [CI]: 0.81-0.95), including unbelted men and drivers younger than 60. The mortality rate was higher, though not statistically significant, for drivers having certified-advanced air bags compared with sled-certified air bags with advanced features (vehicle age-corrected MRR = 1.13; 95% CI: 0.97-1.32) and significantly higher for belted drivers (MRR = 1.21; 95% CI: 1.04-1.39). Advanced air bag features appeared protective for some occupants. However, increased mortality rates among belted drivers of vehicles having certified-advanced air bags relative to those having sled-certified air bags with advanced features suggest that further study is needed to identify any potential problems with requirements for certification. 2010 Elsevier Inc. All rights reserved.

  4. How carryover has an effect on recovery measures related to the area under the curve: theoretical and experimental investigations using cardiovascular parameters.

    PubMed

    Sawada, Yukihiro; Kato, Yuichi

    2011-03-01

    This study examines cardiovascular recovery from mental stress. Investigating the absence or presence of carryover effect, the effect of the final reactivity observed at the end of stressful task on the successive recovery, was the major objective. A recently advocated recovery measure related to the area under the curve, mean recovery rate (MRR), was investigated, comparing with the two relatives of this type, total carryover (TCO) and literally area under the curve (AUC). At the onset, a detailed theoretical formulation of each measure was carried out, starting from its original definition. It was predicted that MRR, but not TCO or AUC, could be free from the carryover effect. Next, 88 male students underwent a 5-min mental arithmetic during which blood pressure and heart rate were measured. Nearly all the theoretical predictions (i.e., 5/6 for the three recovery measures by two cardiovascular parameters) were supported by experimental data. There was only one exception: for heart rate, there was a proportional relationship even for MRR versus the final reactivity. Vagal rebound in the recovery period was conceived as the main contributor of this contradiction. The implications of these results for the understanding of future directions in recovery studies are discussed.

  5. Mark-Release-Recapture Reveals Extensive Movement of Bed Bugs (Cimex lectularius L.) within and between Apartments

    PubMed Central

    Cooper, Richard; Wang, Changlu; Singh, Narinderpal

    2015-01-01

    Understanding movement and dispersal of the common bed bug (Cimex lectularius L.) under field conditions is important in the control of infestations and for managing the spread of bed bugs to new locations. We investigated bed bug movement within and between apartments using mark-release-recapture (m-r-r) technique combined with apartment-wide monitoring using pitfall-style interceptors. Bed bugs were collected, marked, and released in six apartments. The distribution of marked and unmarked bed bugs in these apartments and their 24 neighboring units were monitored over 32 days. Extensive movement of marked bed bugs within and between apartments occurred regardless of the number of bed bugs released or presence/absence of a host. Comparison of marked and unmarked bed bug distributions confirms that the extensive bed bug activity observed was not an artifact of the m-r-r technique used. Marked bed bugs were recovered in apartments neighboring five of six m-r-r apartments. Their dispersal rates at 14 or 15 d were 0.0–5.0%. The estimated number of bed bugs per apartment in the six m-r-r apartments was 2,433–14,291 at 4–7 d after release. Longevity of bed bugs in the absence of a host was recorded in a vacant apartment. Marked large nymphs (3rd– 5th instar), adult females, and adult males continued to be recovered up to 57, 113, and 134 d after host absence, respectively. Among the naturally existing unmarked bed bugs, unfed small nymphs (1st– 2nd instar) were recovered up to 134 d; large nymphs and adults were still found at 155 d when the study ended. Our findings provide important insight into the behavioral ecology of bed bugs in infested apartments and have significant implications in regards to eradication programs and managing the spread of bed bugs within multi-occupancy dwellings. PMID:26352145

  6. Reliability of medical record abstraction by non-physicians for orthopedic research.

    PubMed

    Mi, Michael Y; Collins, Jamie E; Lerner, Vladislav; Losina, Elena; Katz, Jeffrey N

    2013-06-09

    Medical record review (MRR) is one of the most commonly used research methods in clinical studies because it provides rich clinical detail. However, because MRR involves subjective interpretation of information found in the medical record, it is critically important to understand the reproducibility of data obtained from MRR. Furthermore, because medical record review is both technically demanding and time intensive, it is important to establish whether trained research staff with no clinical training can abstract medical records reliably. We assessed the reliability of abstraction of medical record information in a sample of patients who underwent total knee replacement (TKR) at a referral center. An orthopedic surgeon instructed two research coordinators (RCs) in the abstraction of inpatient medical records and operative notes for patients undergoing primary TKR. The two RCs and the surgeon each independently reviewed 75 patients' records and one RC reviewed the records twice. Agreement was assessed using the proportion of items on which reviewers agreed and the kappa statistic. The kappa for agreement between the surgeon and each RC ranged from 0.59 to 1 for one RC and 0.49 to 1 for the other; the percent agreement ranged from 82% to 100% for one RC and 70% to 100% for the other. The repeated abstractions by the same RC showed high intra-rater agreement, with kappas ranging from 0.66 to 1 and percent agreement ranging from 97% to 100%. Inter-rater agreement between the two RCs was moderate with kappa ranging from 0.49 to 1 and percent agreement ranging from 76% to 100%. The MRR method used in this study showed excellent reliability for abstraction of information that had low technical complexity and moderate to good reliability for information that had greater complexity. Overall, these findings support the use of non-surgeons to abstract surgical data from operative notes.

  7. Does oral polio vaccine have non-specific effects on all-cause mortality? Natural experiments within a randomised controlled trial of early measles vaccine.

    PubMed

    Aaby, Peter; Andersen, Andreas; Martins, Cesário L; Fisker, Ane B; Rodrigues, Amabelia; Whittle, Hilton C; Benn, Christine S

    2016-12-23

    BCG and measles vaccine (MV) may have beneficial non-specific effects (NSEs). If an unplanned intervention with a vaccine (a natural experiment) modifies the estimated effect in a randomised controlled trial (RCT), this suggests NSEs. We used this approach to test NSEs of triple oral polio vaccine (OPV). During an RCT of 2 doses of MV at 4.5 and 9 months versus 1 dose of MV at 9 months of age, we experienced 2 natural experiments with OPV. We assessed whether these OPV experiments modified the effect of 2-dose MV in the MV trial. MV RCT conducted in urban Guinea-Bissau 2003-2009. Natural experiments with OPV due to missing vaccine and the implementation of OPV campaigns. Changes in the mortality rate ratio (MRR) for 2-dose MV versus 1-dose MV. First, the MRR (2-dose/1-dose MV) overall was 0.70 (0.52 to 0.94), but the MRR was 1.04 (0.53 to 2.04) when OPV at birth (OPV0) was not given, suggesting that early priming with OPV was important for the effect of 2-dose MV. The effect of OPV0 depended on age of administration; the MRR (2-dose/1-dose MV) was 0.45 (0.29 to 0.71) for children receiving OPV0 in the first week of life, but 3.63 (0.87 to 15.2) for those receiving OPV0 after the first month of life (p=0.007, test of no interaction). Second, campaign-OPV may have reduced the difference between the randomisation groups since the MRR (2-dose/1-dose MV) was 0.60 (0.42 to 0.85) for children who had not received campaign-OPV before RCT-enrolment versus 0.72 (0.23 to 2.31) and 1.42 (0.70 to 2.90) for children who had received 1 or 2 doses of campaign-OPV-before-enrolment, respectively. Bissau had no polio infection during this trial, so OPV0 and campaign-OPV may have NSEs since they modified the effect of 2-dose MV in an RCT. Different interventions may interact to a much larger effect than usually assumed. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  8. Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study.

    PubMed

    Raaschou-Nielsen, Ole; Andersen, Zorana Jovanovic; Jensen, Steen Solvang; Ketzel, Matthias; Sørensen, Mette; Hansen, Johnni; Loft, Steffen; Tjønneland, Anne; Overvad, Kim

    2012-09-05

    Traffic air pollution has been linked to cardiovascular mortality, which might be due to co-exposure to road traffic noise. Further, personal and lifestyle characteristics might modify any association. We followed up 52 061 participants in a Danish cohort for mortality in the nationwide Register of Causes of Death, from enrollment in 1993-1997 through 2009, and traced their residential addresses from 1971 onwards in the Central Population Registry. We used dispersion-modelled concentration of nitrogen dioxide (NO₂) since 1971 as indicator of traffic air pollution and used Cox regression models to estimate mortality rate ratios (MRRs) with adjustment for potential confounders. Mean levels of NO₂ at the residence since 1971 were significantly associated with mortality from cardiovascular disease (MRR, 1.26; 95% confidence interval [CI], 1.06-1.51, per doubling of NO₂ concentration) and all causes (MRR, 1.13; 95% CI, 1.04-1.23, per doubling of NO₂ concentration) after adjustment for potential confounders. For participants who ate < 200 g of fruit and vegetables per day, the MRR was 1.45 (95% CI, 1.13-1.87) for mortality from cardiovascular disease and 1.25 (95% CI, 1.11-1.42) for mortality from all causes. Traffic air pollution is associated with mortality from cardiovascular diseases and all causes, after adjustment for traffic noise. The association was strongest for people with a low fruit and vegetable intake.

  9. Research Registries: A Tool to Advance Understanding of Rare Neuro-Ophthalmic Diseases

    PubMed Central

    Blankshain, Kimberly D; Moss, Heather E

    2016-01-01

    Background Medical research registries (MRR) are organized systems used to collect, store and analyze patient information. They are important tools for medical research with particular application to the study of rare diseases, including those seen in neuro-ophthalmic practice. Evidence Acquisition Evidence for this review was gathered from the writers’ experiences creating a comprehensive neuro-ophthalmology registry and review of the literature. Results MRR are typically observational and prospective databases of de-identified patient information. The structure is flexible and can accommodate a focus on specific diseases or treatments, surveillance of patient populations, physician quality improvement, or recruitment for future studies. They are particularly useful for the study of rare diseases. They can be integrated into the hierarchy of medical research at many levels provided their construction is well organized and they have several key characteristics including an easily manipulated database, comprehensive information on carefully selected patients and comply with human subjects regulations. MRR pertinent to neuro-ophthalmology include the UIC neuro-ophthalmology registry, Susac Syndrome Registry, Intracranial Hypertension Registry as well as larger scale patient outcome registries being developed by professional societies. Conclusion Medical research registries have a variety of forms and applications. With careful planning and clear goals, they are flexible and powerful research tools that can support multiple different study designs, and through this have the potential to advance understanding and care of neuro-ophthalmic diseases. PMID:27389624

  10. Endometrial cancer in relation to coffee, tea, and caffeine consumption: a prospective cohort study among middle-aged women in Sweden.

    PubMed

    Weiderpass, Elisabete; Sandin, Sven; Lof, Marie; Oh, Jin-Kyoung; Inoue, Manami; Shimazu, Taichi; Tsugane, Shoichiro; Adami, Hans-Olov

    2014-01-01

    This study aimed to add to prospective data on the possible inverse association between coffee consumption and endometrial cancer risk, already supported by several case-control studies. Coffee and tea consumption and possible confounding factors were assessed among 42,270 women aged 30-49 years at enrollment in 1991-1992 in the Swedish Women's Lifestyle and Health cohort study, with complete follow-up through 2009. We calculated caffeine intake per day; Cox proportional hazard models were used to estimate multivariable relative risks (mRR) for endometrial cancer with 95% confidence intervals (CIs). One hundred forty-four endometrial cancers were diagnosed during follow-up. Women with and without endometrial cancer had a similar mean daily coffee consumption (549 vs. 547 g), tea consumption (104 vs. 115 g), and caffeine intake (405 vs. 406 mg). Compared to those consuming <2 cups of coffee per day, women consuming >3 cups had a mRR of 1.56 (95% CI: 0.94-2.59; P for trend = 0.17). Compared with the lowest tertile of caffeine intake, the highest tertile had a mRR of 1.32 (95% CI: 0.87-1.99; P for trend = 0.27). Our study provides no convincing evidence of an association between coffee consumption, tea consumption, or caffeine intake and endometrial cancer risk among middle-aged women.

  11. Healthcare Text Classification System and its Performance Evaluation: A Source of Better Intelligence by Characterizing Healthcare Text.

    PubMed

    Srivastava, Saurabh Kumar; Singh, Sandeep Kumar; Suri, Jasjit S

    2018-04-13

    A machine learning (ML)-based text classification system has several classifiers. The performance evaluation (PE) of the ML system is typically driven by the training data size and the partition protocols used. Such systems lead to low accuracy because the text classification systems lack the ability to model the input text data in terms of noise characteristics. This research study proposes a concept of misrepresentation ratio (MRR) on input healthcare text data and models the PE criteria for validating the hypothesis. Further, such a novel system provides a platform to amalgamate several attributes of the ML system such as: data size, classifier type, partitioning protocol and percentage MRR. Our comprehensive data analysis consisted of five types of text data sets (TwitterA, WebKB4, Disease, Reuters (R8), and SMS); five kinds of classifiers (support vector machine with linear kernel (SVM-L), MLP-based neural network, AdaBoost, stochastic gradient descent and decision tree); and five types of training protocols (K2, K4, K5, K10 and JK). Using the decreasing order of MRR, our ML system demonstrates the mean classification accuracies as: 70.13 ± 0.15%, 87.34 ± 0.06%, 93.73 ± 0.03%, 94.45 ± 0.03% and 97.83 ± 0.01%, respectively, using all the classifiers and protocols. The corresponding AUC is 0.98 for SMS data using Multi-Layer Perceptron (MLP) based neural network. All the classifiers, the best accuracy of 91.84 ± 0.04% is shown to be of MLP-based neural network and this is 6% better over previously published. Further we observed that as MRR decreases, the system robustness increases and validated by standard deviations. The overall text system accuracy using all data types, classifiers, protocols is 89%, thereby showing the entire ML system to be novel, robust and unique. The system is also tested for stability and reliability.

  12. Facility-level variation in diabetes and blood pressure control in patients with diabetes: Findings from the Veterans Affairs national database.

    PubMed

    Rehman, Hasan; Akeroyd, Julia M; Ramsey, David; Ahmed, Sarah T; Merchant, Anwar T; Navaneethan, Sankar D; Petersen, Laura A; Virani, Salim S

    2017-11-01

    Intensive glycemic and blood pressure (BP) control in diabetic patients is associated with improved cardiovascular outcomes. We hypothesized that there is suboptimal glycemic and BP control with significant facility-level variation in patients with diabetes. We identified patients with diabetes receiving care in 130 facilities in the Veterans Affairs Health Care System. We assessed facility-level rates of glycemic (hemoglobin [Hb]A1c <7%), BP (BP <140/90 mmHg), and combined glycemic and BP control (HbA1c <7% and BP <140/90 mmHg), and their facility-level variation in using median rate ratios (MRR). Among 1 103 302 patients with diabetes, 50.2% participants had an HbA1c <7%, 77.5% had a BP <140/90 mmHg, and 39.8% had both, HbA1c <7% and BP <140/90 mmHg. Median facility-level rates were 50.3% (interquartile range [IQR], 47.9%-52.4%) for glycemic control, 78.4% (IQR, 75.2%-80.0%) for BP control, and 39.9% (IQR, 38.14%-42.34%) for combined glycemic and BP control. Unadjusted MRR for glycemic control was 1.61 (95% confidence interval [CI]: 1.51-1.70) which decreased to 1.16 (95% CI: 1.14-1.19) after adjusting for patient and facility-level variables, indicating a 16% variation in glycemic control between 2 identical patients receiving care at 2 random facilities. Unadjusted MRR for BP control was 1.49 (95% CI: 1.41-1.56), which decreased to 1.25 (95% CI: 1.21-1.28), whereas unadjusted MRR for combined glycemic and BP control was 1.59 (95% CI: 1.50-1.68), which decreased to 1.15 (95% CI: 1.13-1.17) after adjustment. Facility-level rates for BP control and glycemic control remain low with significant facility-level variation. Much of this is explained by patient and facility-level variables although 16%, 25%, and 15% variation in glycemic, BP, and combined glycemic and BP control remains unexplained. © 2017 Wiley Periodicals, Inc.

  13. Mobile Phones and Multiple Sclerosis – A Nationwide Cohort Study in Denmark

    PubMed Central

    Harbo Poulsen, Aslak; Stenager, Egon; Johansen, Christoffer; Bentzen, Joan; Friis, Søren; Schüz, Joachim

    2012-01-01

    We investigated the risk of, prognosis of and symptoms of multiple sclerosis (MS) among all Danish residents who owned a mobile phone subscription before 1996. Using the Danish Multiple Sclerosis Registry and Civil Registration System, study subjects were followed up for MS through 2004. Poisson models were used to calculate incidence rate ratios (IRR, age range: 18–64 years) and mortality rate ratios (MRR, age range: 18+) and to compare presenting symptoms among subscribers and all non-subscribers. A total of 405 971 subscription holders accrued four million years of follow up, with men accounting for 86% of the observation time. Among subscription holding men, the IRR of MS was close to unity, overall as well as 13+ years after first subscription (IRR 1.02, 95% CI: 0.48–2.16). Among women, the IRR was 3.43 (95% CI: 0.86–13.72) 13+ years after first subscription, however, based on only two cases. Presenting symptoms of MS differed between subscribers and non-subscribers (p = 0.03), with slightly increased risk of diplopia in both genders (IRR: 1.38, 95% CI: 1.02–1.86), an increased risk of fatigue among women (IRR: 3.02, 95% CI: 1.45–6.28), and of optic neuritis among men (IRR: 1.38, 95% CI: 1.03–1.86). Overall the MRR was close to one (MRR: 0.91, 95%CI 0.70–1.19) among MS-patients with a subscription and although we observed some increased MRR estimates among women, these were based on small numbers. In conclusion, we found little evidence for a pronounced association between mobile phone use and risk of MS or mortality rate among MS patients. Symptoms of MS differed between subscribers and nonsubscribers for symptoms previously suggested to be associated with mobile phone use. This deserves further attention, as does the increased long-term risk of MS among female subscribers, although small numbers and lack of consistency between genders prevent causal interpretation. PMID:22558088

  14. The Mars Astrobiology Explorer-Cacher (MAX-C): a potential rover mission for 2018. Final report of the Mars Mid-Range Rover Science Analysis Group (MRR-SAG) October 14, 2009.

    PubMed

    2010-03-01

    This report documents the work of the Mid-Range Rover Science Analysis Group (MRR-SAG), which was assigned to formulate a concept for a potential rover mission that could be launched to Mars in 2018. Based on programmatic and engineering considerations as of April 2009, our deliberations assumed that the potential mission would use the Mars Science Laboratory (MSL) sky-crane landing system and include a single solar-powered rover. The mission would also have a targeting accuracy of approximately 7 km (semimajor axis landing ellipse), a mobility range of at least 10 km, and a lifetime on the martian surface of at least 1 Earth year. An additional key consideration, given recently declining budgets and cost growth issues with MSL, is that the proposed rover must have lower cost and cost risk than those of MSL--this is an essential consideration for the Mars Exploration Program Analysis Group (MEPAG). The MRR-SAG was asked to formulate a mission concept that would address two general objectives: (1) conduct high priority in situ science and (2) make concrete steps toward the potential return of samples to Earth. The proposed means of achieving these two goals while balancing the trade-offs between them are described here in detail. We propose the name Mars Astrobiology Explorer-Cacher(MAX-C) to reflect the dual purpose of this potential 2018 rover mission.

  15. Concrete bridge deck condition assessment and improvement strategies.

    DOT National Transportation Integrated Search

    2004-11-01

    The aging and deterioration of bridges in Utah mandates increasingly cost-effective strategies for bridge maintenance, rehabilitation, and repair (MR&R). Although the substructures and superstructures of bridges in Utah are in relatively good structu...

  16. Protein secondary structure prediction using modular reciprocal bidirectional recurrent neural networks.

    PubMed

    Babaei, Sepideh; Geranmayeh, Amir; Seyyedsalehi, Seyyed Ali

    2010-12-01

    The supervised learning of recurrent neural networks well-suited for prediction of protein secondary structures from the underlying amino acids sequence is studied. Modular reciprocal recurrent neural networks (MRR-NN) are proposed to model the strong correlations between adjacent secondary structure elements. Besides, a multilayer bidirectional recurrent neural network (MBR-NN) is introduced to capture the long-range intramolecular interactions between amino acids in formation of the secondary structure. The final modular prediction system is devised based on the interactive integration of the MRR-NN and the MBR-NN structures to arbitrarily engage the neighboring effects of the secondary structure types concurrent with memorizing the sequential dependencies of amino acids along the protein chain. The advanced combined network augments the percentage accuracy (Q₃) to 79.36% and boosts the segment overlap (SOV) up to 70.09% when tested on the PSIPRED dataset in three-fold cross-validation. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  17. Drilling of Hybrid Titanium Composite Laminate (HTCL) with Electrical Discharge Machining.

    PubMed

    Ramulu, M; Spaulding, Mathew

    2016-09-01

    An experimental investigation was conducted to determine the application of die sinker electrical discharge machining (EDM) as it applies to a hybrid titanium thermoplastic composite laminate material. Holes were drilled using a die sinker EDM. The effects of peak current, pulse time, and percent on-time on machinability of hybrid titanium composite material were evaluated in terms of material removal rate (MRR), tool wear rate, and cut quality. Experimental models relating each process response to the input parameters were developed and optimum operating conditions with a short cutting time, achieving the highest workpiece MRR, with very little tool wear were determined to occur at a peak current value of 8.60 A, a percent on-time of 36.12%, and a pulse time of 258 microseconds. After observing data acquired from experimentation, it was determined that while use of EDM is possible, for desirable quality it is not fast enough for industrial application.

  18. Drilling of Hybrid Titanium Composite Laminate (HTCL) with Electrical Discharge Machining

    PubMed Central

    Ramulu, M.; Spaulding, Mathew

    2016-01-01

    An experimental investigation was conducted to determine the application of die sinker electrical discharge machining (EDM) as it applies to a hybrid titanium thermoplastic composite laminate material. Holes were drilled using a die sinker EDM. The effects of peak current, pulse time, and percent on-time on machinability of hybrid titanium composite material were evaluated in terms of material removal rate (MRR), tool wear rate, and cut quality. Experimental models relating each process response to the input parameters were developed and optimum operating conditions with a short cutting time, achieving the highest workpiece MRR, with very little tool wear were determined to occur at a peak current value of 8.60 A, a percent on-time of 36.12%, and a pulse time of 258 microseconds. After observing data acquired from experimentation, it was determined that while use of EDM is possible, for desirable quality it is not fast enough for industrial application. PMID:28773866

  19. Dual-pump Kerr Micro-cavity Optical Frequency Comb with varying FSR spacing

    PubMed Central

    Wang, Weiqiang; Chu, Sai T.; Little, Brent E.; Pasquazi, Alessia; Wang, Yishan; Wang, Leiran; Zhang, Wenfu; Wang, Lei; Hu, Xiaohong; Wang, Guoxi; Hu, Hui; Su, Yulong; Li, Feitao; Liu, Yuanshan; Zhao, Wei

    2016-01-01

    In this paper, we demonstrate a novel dual-pump approach to generate robust optical frequency comb with varying free spectral range (FSR) spacing in a CMOS-compatible high-Q micro-ring resonator (MRR). The frequency spacing of the comb can be tuned by an integer number FSR of the MRR freely in our dual-pump scheme. The dual pumps are self-oscillated in the laser cavity loop and their wavelengths can be tuned flexibly by programming the tunable filter embedded in the cavity. By tuning the pump wavelength, broadband OFC with the bandwidth of >180 nm and the frequency-spacing varying from 6 to 46-fold FSRs is realized at a low pump power. This approach could find potential and practical applications in many areas, such as optical metrology, optical communication, and signal processing systems, for its excellent flexibility and robustness. PMID:27338250

  20. Evaluating the Efficacy of Lay Health Advisors for Increasing Risk-appropriate Pap Test Screening: A randomized controlled trial among Ohio Appalachian women

    PubMed Central

    Paskett, Electra D.; McLaughlin, John M.; Lehman, Amy M.; Katz, Mira L.; Tatum, Cathy M.; Oliveri, Jill M.

    2011-01-01

    Background Cervical cancer is a significant health disparity among women in Ohio Appalachia. The goal of this study was to evaluate the efficacy of a lay health advisor (LHA) intervention for improving Pap testing rates, to reduce cervical cancer, among women in need of screening. Methods Women from 14 Ohio Appalachian clinics in need of a Pap test were randomized to receive either usual care or an LHA intervention over a ten-month period. The intervention consisted of two in-person visits with an LHA, two phone calls, and four post cards. Both self-report and medical record review (MRR) data (primary outcome) were analyzed. Results Of the 286 women, 145 and 141 were randomized to intervention and usual care arms, respectively. According to MRR, more women in the LHA arm had a Pap test by the end of the study compared to those randomized to usual care (51.1% vs. 42.0%; OR=1.44, 95%CI: 0.89, 2.33; p=0.135). Results of self-report were more pronounced (71.3% vs. 54.2%; OR=2.10, 95%CI: 1.22, 3.61; p=0.008). Conclusions An LHA intervention showed some improvement in the receipt of Pap tests among Ohio Appalachian women in need of screening. While biases inherent in using self-reports of screening are well known, this study also identified biases in using MRR data in clinics located in underserved areas. Impact LHA interventions show promise for improving screening behaviors among non-adherent women from underserved populations. PMID:21430302

  1. Optimization of Processing Parameters in ECM of Die Tool Steel Using Nanofluid by Multiobjective Genetic Algorithm.

    PubMed

    Sathiyamoorthy, V; Sekar, T; Elango, N

    2015-01-01

    Formation of spikes prevents achievement of the better material removal rate (MRR) and surface finish while using plain NaNO3 aqueous electrolyte in electrochemical machining (ECM) of die tool steel. Hence this research work attempts to minimize the formation of spikes in the selected workpiece of high carbon high chromium die tool steel using copper nanoparticles suspended in NaNO3 aqueous electrolyte, that is, nanofluid. The selected influencing parameters are applied voltage and electrolyte discharge rate with three levels and tool feed rate with four levels. Thirty-six experiments were designed using Design Expert 7.0 software and optimization was done using multiobjective genetic algorithm (MOGA). This tool identified the best possible combination for achieving the better MRR and surface roughness. The results reveal that voltage of 18 V, tool feed rate of 0.54 mm/min, and nanofluid discharge rate of 12 lit/min would be the optimum values in ECM of HCHCr die tool steel. For checking the optimality obtained from the MOGA in MATLAB software, the maximum MRR of 375.78277 mm(3)/min and respective surface roughness Ra of 2.339779 μm were predicted at applied voltage of 17.688986 V, tool feed rate of 0.5399705 mm/min, and nanofluid discharge rate of 11.998816 lit/min. Confirmatory tests showed that the actual performance at the optimum conditions was 361.214 mm(3)/min and 2.41 μm; the deviation from the predicted performance is less than 4% which proves the composite desirability of the developed models.

  2. Long-term mortality in children diagnosed with Haemophilus influenzae meningitis: a Danish nationwide cohort study.

    PubMed

    Roed, Casper; Engsig, Frederik Neess; Omland, Lars Haukali; Skinhoj, Peter; Obel, Niels

    2011-08-01

    The long-term mortality in children diagnosed with Haemophilus influenzae meningitis is poorly documented. We performed a nationwide, population-based cohort study including all Danish children diagnosed at the age between 0 and <5 years with H. influenzae meningitis from 1977 through 1996 and who were alive 1 year after diagnosis. Data were retrieved from medical databases in Denmark. For each H. influenzae meningitis patient, 6 age- and gender-matched population controls were indentified. We constructed Kaplan-Meier survival curves and used Cox regression analysis to estimate mortality rate ratios (MRR) and analyze causes of death. The risk of inpatient admission and of requiring hospital outpatient services during follow-up was calculated. We identified 1242 H. influenzae meningitis patients and 7452 population controls, with a median follow-up time of 21.3 years. The MRR for patients with H. influenzae meningitis was 1.08 (95% confidence interval, 0.57-2.05), adjusted MRR was 0.97 (95% confidence interval, 0.50-1.89). No increased mortality due to infections, respiratory diseases, or cancer was observed. The overall risk of inpatient admission and of requiring hospital outpatient services for the H. influenzae meningitis patients was increased the first 15 years of follow-up, mainly due to the nervous system diseases and ear diseases, thereafter the risk decreased to that of the population controls. In a developed country, children younger than 5 years surviving the acute phase of H. influenzae meningitis have no increased long-term mortality and only moderately increased morbidity.

  3. Evaluation of a device for standardized measurements of reading performance in a prepresbyopic population.

    PubMed

    Arad, Tschingis; Baumeister, Martin; Bühren, Jens; Kohnen, Thomas

    2017-04-20

    Automated measurements of reading performance are required for clinical trials involving presbyopia-correcting surgery options. Repeatability of a testing device for reading (Salzburg Reading Desk) was evaluated in a prepresbyopic population. Subjective reading performance of 50 subjects divided into 2 age groups (23-30 years and 38-49 years) with distance-corrected eyes was investigated with different log-scaled reading charts. At study entry, refractive parameters were measured and distance visual acuity assessed. Two standardized binocular measurements were performed for each subject (32.24 ± 9.87 days apart [mean ± SD]). The repeatability of the tests was estimated using correlation coefficients, Wilcoxon signed-rank test, and Bland-Altman method. The test parameters at both maximum reading rate (MRR) measurements demonstrate a strong relationship of age group 2 subjects (correlation coefficient [r] = 0.74 p = 10-4) and of younger subjects (age group 1: r = 0.69, p = 10-4). Prepresbyopic subjects of age group 2 showed moderate results for near reading distance (r = 0.67, p = 10-4); by contrast, younger subjects had poorer results (r = 0.55, p = 10-3). The Wilcoxon signed-rank test revealed agreement between measurements and Bland-Altman plots showed a wide data spread for MRR and near reading distance in both groups. The device measures repeatedly selected reading performance parameters of near real world conditions, such as MRR, in prepresbyopic populations if several factors are taken into account. The option to choose preferred distance leads to more variance in measuring repeated reading performance. German Clinical Trials Register (DRKS) registration reference number: DRKS00000784.

  4. Panitumumab use in metastatic colorectal cancer and patterns of RAS testing: results from a Europe-wide physician survey and medical records review.

    PubMed

    Han van Krieken, J; Kafatos, George; Bennett, James; Mineur, Laurent; Tomášek, Jiří; Rouleau, Etienne; Fabian, Pavel; De Maglio, Giovanna; García-Alfonso, Pilar; Aprile, Giuseppe; Parkar, Parijan; Downey, Gerald; Demonty, Gaston; Trojan, Jörg

    2017-11-28

    In Europe, treatment of metastatic colorectal cancer (mCRC) with panitumumab requires prior confirmation of RAS wild-type mutation status. Two studies - a physician survey and a medical records review (MRR) - were conducted to evaluate the use of panitumumab and awareness among prescribing oncologists of the associated RAS testing requirements in clinical practice. Both studies enrolled participants from nine European countries and were carried out in three consecutive rounds. Rounds 1 and 2 (2012-2013) examined KRAS (exon 2) testing only; the results have been published in full previously. Round 3 (2014-2015) examined full RAS testing (exons 2, 3, 4 of KRAS and NRAS) and was initiated following a change in prescribing guidelines, from requiring KRAS alone to requiring full RAS testing. For the physician survey, telephone interviews were conducted with oncologists who had prescribed panitumumab to patients with mCRC in the previous 6 months. For the MRR, oncologists were asked to provide anonymised clinical information, extracted from their patients' records. In Round 3, 152 oncologists and 131 patients' records were included in the physician survey and MRR, respectively. In Round 3 of the physician survey, 95.4% (n = 145) of participants correctly identified that panitumumab should only be prescribed in RAS wild-type mCRC compared with 99.0% (n = 298) of 301 participants in Rounds 1 and 2, responding to the same question about KRAS testing. In Round 3 of the MRR, 100% (n = 131) of patients included in the study had confirmed KRAS or RAS wild-type status prior to initiation of panitumumab compared with 97.7% (n = 299) of 306 patients in Rounds 1 and 2 (KRAS only). Of those patients in Round 3, 83.2% (n = 109) had been tested for RAS status and 16.8% (n = 22) had been tested for KRAS status only. Physicians' adherence to prescribing guidelines has remained high over time in Europe, despite the change in indication for panitumumab treatment, from KRAS to RAS wild-type mCRC. Additionally, this study demonstrates the uptake of full RAS testing among the majority of oncologists and pathologists.

  5. Leaving A Mark: A Comparison Arthropod Protein Marking Protocols

    USDA-ARS?s Scientific Manuscript database

    Knowledge of arthropod pest and natural enemy disperal patterns is needed for effective and environmentally benign pest control. The most common tactics used to monitor arthropod dispersal patterns include mark-release-recapture (MRR) and mark-capture methodologies. Both methods require the applica...

  6. Innovative techniques for maintenance, repair and reconstruction (MRR) of asphalt roadways : final report.

    DOT National Transportation Integrated Search

    2017-08-01

    Highway networks in the United States have been suffering from poor operational and structural condition states for the past decades. The consequent congestion problems often result in major delays, safety issues, and large amounts of additional fuel...

  7. Measles vaccination in the presence or absence of maternal measles antibody: impact on child survival.

    PubMed

    Aaby, Peter; Martins, Cesário L; Garly, May-Lill; Andersen, Andreas; Fisker, Ane B; Claesson, Mogens H; Ravn, Henrik; Rodrigues, Amabelia; Whittle, Hilton C; Benn, Christine S

    2014-08-15

    Measles vaccine (MV) has a greater effect on child survival when administered in early infancy, when maternal antibody may still be present. To test whether MV has a greater effect on overall survival if given in the presence of maternal measles antibody, we reanalyzed data from 2 previously published randomized trials of a 2-dose schedule with MV given at 4-6 months and at 9 months of age. In both trials antibody levels had been measured before early measles vaccination. In trial I (1993-1995), the mortality rate was 0.0 per 1000 person-years among children vaccinated with MV in the presence of maternal antibody and 32.3 per 1000 person-years without maternal antibody (mortality rate ratio [MRR], 0.0; 95% confidence interval [CI], 0-.52). In trial II (2003-2007), the mortality rate was 4.2 per 1000 person-years among children vaccinated in presence of maternal measles antibody and 14.5 per 1000 person-years without measles antibody (MRR, 0.29; 95% CI, .09-.91). Possible confounding factors did not explain the difference. In a combined analysis, children who had measles antibody detected when they received their first dose of MV at 4-6 months of age had lower mortality than children with no maternal antibody, the MRR being 0.22 (95% CI, .07-.64) between 4-6 months and 5 years. Child mortality in low-income countries may be reduced by vaccinating against measles in the presence of maternal antibody, using a 2-dose schedule with the first dose at 4-6 months (earlier than currently recommended) and a booster dose at 9-12 months of age. NCT00168558. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America.

  8. Weight fluctuation, mortality and vascular disease in Pima Indians.

    PubMed

    Hanson, R L; Jacobsson, L T; McCance, D R; Narayan, K M; Pettitt, D J; Bennett, P H; Knowler, W C

    1996-05-01

    To examine the relationship of weight fluctuation to mortality rates and incidence of vascular disease. A cohort of Pima Indians, 572 of whom had non-insulin-dependent diabetes mellitus and 766 without diabetes. Individuals were invited biennially to research examinations. The root mean square error (RMSE) of the linear trend of weight with time for the first four examinations after age 20 years was used as an index of weight fluctuation. Subjects were followed from the fourth examination until death or until 31 December 1991. The mortality rate ratio (MRR) and its 95% confidence interval (CI) for those with a high weight fluctuation index relative to those with a lower value were determined. The median duration of follow up was 9.3 (range 0.1-22.6) years. All cause mortality (n = 356); incidence of diabetic retinopathy (n = 145), diabetic nephropathy (n = 132) and electrocardiographic abnormalities (n = 82). There was no significant relationship between weight fluctuation and mortality for diabetic subjects (MRR = 1.0, 95% CI 0.8-1.3, p = 0.91). Nondiabetic subjects with a high weight fluctuation index had a higher mortality rate than those with a lower index (MRR = 1.5, 95% CI 1.0-2.1, p = 0.03); the association was stronger among men than among women. The excess mortality in the high weight fluctuation group was not due to cardiovascular diseases, but to noncardiovascular causes and the risk for alcohol-related death was particularly increased. Weight fluctuation was not associated with the incidence of diabetic retinopathy, nephropathy or electrocardiographic abnormalities. A high weight fluctuation index was associated with higher mortality rates in nondiabetic, but not in diabetic, Pima Indians. The excess mortality is largely due to noncardiovascular causes of death and may reflect lifestyle factors associated with weight fluctuation, rather than its metabolic effects.

  9. Correlates of opium use: retrospective analysis of a survey of tribal communities in Arunachal Pradesh, India

    PubMed Central

    2013-01-01

    Background Household survey data of Changlang district, Arunachal Pradesh, were used in the present study to assess the prevalence of opium use among different tribes, and to examine the association between sociodemographic factors and opium use. Methods A sample of 3421 individuals (1795 men and 1626 women) aged 15 years and older was analyzed using a multivariate logistic regression model to determine factors associated with opium use. Sociodemographic information such as age, education, occupation, religion, ethnicity and marital status were included in the analysis. Results The prevalence of opium use was significantly higher (10.6%) among men than among women (2.1%). It varied according to age, educational level, occupation, marital status and religion of the respondents. In both sexes, opium use was significantly higher among Singpho and Khamti tribes compared with other tribes. Multivariate logistic regression indicated that opium use was significantly associated with age, occupation, ethnicity, religion and marital status of the respondents of both sexes. Multivariate rate ratios (MRR) for opium use were significantly higher (4–6 times) among older age groups (≥35 years) and male respondents. In males, the MRR was also significantly higher in respondents of Buddhist and Indigenous religion, while in females, the MRR was significantly higher in Buddhists. Most of the female opium users had taken opium for more than 5 years and were introduced to it by their husbands after marriage. Use of other substances among opium users comprised mainly tobacco (76%) and alcohol (44%). Conclusions The study reveals the sociodemographic factors, such as age, sex, ethnicity, religion and occupation, which are associated with opium use. Such information is useful for institution of intervention measures to reduce opium use. PMID:23575143

  10. Site of metastasis and breast cancer mortality: a Danish nationwide registry-based cohort study.

    PubMed

    Ording, Anne Gulbech; Heide-Jørgensen, Uffe; Christiansen, Christian Fynbo; Nørgaard, Mette; Acquavella, John; Sørensen, Henrik Toft

    2017-01-01

    Survival among patients with metastatic breast cancer may vary according to the site of metastasis and receptor status. We used Danish nationwide medical registries to establish a cohort of patients with metastatic breast cancer (870 with de novo metastatic disease and 3518 with recurrent disease with distant metastasis) diagnosed during 1997-2011. We examined 1-year and >1 to 5-year mortality associated with first site of metastasis and receptor expression status of the primary tumor. Cox proportional regression was used to compute confounder-adjusted mortality rate ratios (MRRs) associated with site of metastasis, stratified by receptor status. Overall 1-year and >1 to 5-year mortality risks were 36 and 69 %, respectively. Risk of death within 1 year was highest for brain-only (62 %) and liver-only (43 %) involvement and nearly the same for patients with lung-only (32 %), bone-only (32 %) involvement, and other/combination of sites (34 %). Using bone-only metastasis as reference, women with brain-only metastasis had more than two-fold increased risk of dying. The adjusted MRR for women with liver-only metastasis also was increased, though less pronounced. Patients with lung-only [adjusted MRR 0.9 (95 % confidence interval (CI) 0.8, 1.1)] or other metastases [adjusted MRR 1.0 (95 % CI 0.9, 1.2)] had similar mortality as patients with bone-only metastasis. Positive hormonal receptor status was a favorable prognostic factor. Metastatic breast cancer has a serious prognosis. Patients with brain-only metastasis had the highest mortality. Positive hormonal receptor status on the primary tumor was a favorable prognostic factor for all metastatic sites.

  11. Conversion between network-level and project-level units of measure for use in a bridge-management system.

    DOT National Transportation Integrated Search

    1998-01-01

    VDOT is implementing Pontis 3.0 to provide the analytical component of its Bridge Management System (BMS). This system prioritizes bridge maintenance, repair, rehabilitation, and replacement (MRR & R) needs using cost/benefit analysis. The accuracy o...

  12. Rectangular optical filter based on high-order silicon microring resonators

    NASA Astrophysics Data System (ADS)

    Bao, Jia-qi; Yu, Kan; Wang, Li-jun; Yin, Juan-juan

    2017-07-01

    The rectangular optical filter is one of the most important optical switching components in the dense wavelength division multiplexing (DWDM) fiber-optic communication system and the intelligent optical network. The integrated highorder silicon microring resonator (MRR) is one of the best candidates to achieve rectangular filtering spectrum response. In general, the spectrum response rectangular degree of the single MRR is very low, so it cannot be used in the DWDM system. Using the high-order MRRs, the bandwidth of flat-top pass band, the out-of-band rejection degree and the roll-off coefficient of the edge will be improved obviously. In this paper, a rectangular optical filter based on highorder MRRs with uniform couplers is presented and demonstrated. Using 15 coupled race-track MRRs with 10 μm in radius, the 3 dB flat-top pass band of 2 nm, the out-of-band rejection ratio of 30 dB and the rising and falling edges of 48 dB/nm can be realized successfully.

  13. 78 FR 8119 - Cancellation of the Notice of Intent To Prepare a Draft and Final Supplemental Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... the Herbert Hoover Dike Major Rehabilitation Project, Martin and Palm Beach Counties AGENCY...-wide risk reduction approach as required for safety modifications to dams. FOR FURTHER INFORMATION...-2108. SUPPLEMENTARY INFORMATION: The supplemental MRR will be replaced with a system-wide Dam Safety...

  14. 78 FR 8119 - Cancellation of the Notice of Intent To Prepare a Draft and Final Supplemental Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... the Herbert Hoover Dike Major Rehabilitation Project, Palm Beach and Glades Counties, FL AGENCY... safety modifications to dams. FOR FURTHER INFORMATION CONTACT: Questions may be forwarded to Ms. Angela... supplemental MRR will be replaced with a system wide Dam Safety Modification (DSM) Report. Environmental...

  15. Study on effect of the surface variation of colloidal silica abrasive during chemical mechanical polishing of sapphire

    NASA Astrophysics Data System (ADS)

    Bun-Athuek, Natthaphon; Yoshimoto, Yutaka; Sakai, Koya; Khajornrungruang, Panart; Suzuki, Keisuke

    2017-07-01

    The surface and diameter size variations of colloidal silica particles during the chemical mechanical polishing (CMP) of sapphire substrates were investigated using different particle diameters of 20 and 55 nm. Dynamic light scattering (DLS) results show that the silica particles became larger after CMP under both conditions. The increase in particle size in the slurry was proportional to the material removal amount (MRA) as a function of the removed volume of sapphire substrates by CMP and affected the material removal rate (MRR). Transmission electron microscopy (TEM) images revealed an increase in the size of the fine particles and a change in their surface shape in the slurry. The colloidal silica was coated with the material removed from the substrate during CMP. In this case, the increase in the size of 55 nm diameter particles is larger than that of 20 nm diameter particles. X-ray fluorescence spectrometry (XRF) results indicate that the aluminum element from polished sapphire substrates adhered to the surfaces of silica particles. Therefore, MRR decreases with increasing of polishing time owing to the degradation of particles in the slurry.

  16. Optimization of machining parameters in dry EDM of EN31 steel

    NASA Astrophysics Data System (ADS)

    Brar, G. S.

    2018-03-01

    Dry electric discharge machining (Dry EDM) is one of the novel EDM technology in which gases namely helium, argon, oxygen, nitrogen etc. are used as a dielectric medium at high pressure instead of oil based liquid dielectric. The present study investigates dry electric discharge machining (with rotary tool) of EN-31 steel to achieve lower tool wear rate (TWR) and better surface roughness (Ra) by performing a set of exploratory experiments with oxygen gas as dielectric. The effect of polarity, discharge current, gas flow pressure, pulse-on time, R.P.M. and gap voltage on the MRR, TWR and surface roughness (Ra) in dry EDM was studied with copper as rotary tool. The significant factors affecting MRR are discharge current and pulse on time. The significant factors affecting TWR are gas flow pressure, pulse on time and R.P.M. TWR was found close to zero in most of the experiments. The significant factors affecting Ra are pulse on time, gas flow pressure and R.P.M. It was found that polarity has nearly zero effect on all the three output variables.

  17. Passive bistatic radar analysis

    NASA Astrophysics Data System (ADS)

    O'Hagan, Daniel W.; Kuschel, H.; Schiller, Joachim

    2009-06-01

    Passive Bistatic Radar (PBR) research is at its zenith with several notable PBR systems currently operational, or available for deployment. Such PBRs include the Manastash Ridge Radar (MRR) developed for and by academia; Silent Sentry developed as a commercial concern by Lockheed Martin; and Homeland Alerter (HA100) also a commercial system developed by Thales. However at present, despite the existence of numerous PBR prototypes, take up of commercial passive radar technology remains slow. This is due in part to technology immaturity, in part to politics, and particularly due to the fact that monostatic radars perform so well. If PBRs are to enjoy longevity as a viable technology then it is imperative that they address certain niche application areas, with the aforementioned MRR being one prime example of this. The focus of this paper will be an analysis of a PBR system that utilised FM radio signals of opportunity to detect aircraft targets with an RCS generally not lower than 20 m2. The paper will demonstrate the theoretical detection coverage of an FM based PBR operating in a severe interference environment.

  18. Physician Religion and End-of-Life Pediatric Care: A Qualitative Examination of Physicians' Perspectives.

    PubMed

    Bateman, Lori Brand; Clair, Jeffrey Michael

    2015-01-01

    Physician religion/spirituality has the potential to influence the communication between physicians and parents of children at the end of life. In order to explore this relationship, the authors conducted two rounds of narrative interviews to examine pediatric physicians' perspectives (N=17) of how their religious/spiritual beliefs affect end-of-life communication and care. Grounded theory informed the design and analysis of the study. As a proxy for religiosity/spirituality, physicians were classified into the following groups based on the extent to which religious/spiritual language was infused into their responses: Religiously Rich Responders (RRR), Moderately Religious Responders (MRR), and Low Religious Responders (LRR). Twelve of the 17 participants (71%) were classified into the RRR or MRR groups. The majority of participants suggested that religion/spirituality played a role in their practice of medicine and communication with parents in a myriad of ways and to varying degrees. Participants used their religious/spiritual beliefs to support families' spirituality, uphold hope, participate in prayer, and alleviate their own emotional distress emerging from their patients' deaths.

  19. Measurements of precipitation in Dumont d'Urville, Adélie Land, East Antarctica

    NASA Astrophysics Data System (ADS)

    Grazioli, Jacopo; Genthon, Christophe; Boudevillain, Brice; Duran-Alarcon, Claudio; Del Guasta, Massimo; Madeleine, Jean-Baptiste; Berne, Alexis

    2017-08-01

    The first results of a campaign of intensive observation of precipitation in Dumont d'Urville, Antarctica, are presented. Several instruments collected data from November 2015 to February 2016 or longer, including a polarimetric radar (MXPol), a Micro Rain Radar (MRR), a weighing gauge (Pluvio2), and a Multi-Angle Snowflake Camera (MASC). These instruments collected the first ground-based measurements of precipitation in the region of Adélie Land (Terre Adélie), including precipitation microphysics. Microphysical observations during the austral summer 2015/2016 showed that, close to the ground level, aggregates are the dominant hydrometeor type, together with small ice particles (mostly originating from blowing snow), and that riming is a recurring process. Eleven percent of the measured particles were fully developed graupel, and aggregates had a mean riming degree of about 30 %. Spurious precipitation in the Pluvio2 measurements in windy conditions, leading to phantom accumulations, is observed and partly removed through synergistic use of MRR data. The yearly accumulated precipitation of snow (300 m above ground), obtained by means of a local conversion relation of MRR data, trained on the Pluvio2 measurement of the summer period, is estimated to be 815 mm of water equivalent, with a confidence interval ranging between 739.5 and 989 mm. Data obtained in previous research from satellite-borne radars, and the ERA-Interim reanalysis of the European Centre for Medium-Range Weather Forecasts (ECMWF) provide lower yearly totals: 655 mm for ERA-Interim and 679 mm for the climatological data over DDU. ERA-Interim overestimates the occurrence of low-intensity precipitation events especially in summer, but it compensates for them by underestimating the snowfall amounts carried by the most intense events. Overall, this paper provides insightful examples of the added values of precipitation monitoring in Antarctica with a synergistic use of in situ and remote sensing measurements.

  20. Mortality Among Persons With Obsessive-Compulsive Disorder in Denmark.

    PubMed

    Meier, Sandra M; Mattheisen, Manuel; Mors, Ole; Schendel, Diana E; Mortensen, Preben B; Plessen, Kerstin J

    2016-03-01

    Several mental disorders have consistently been found to be associated with decreased life expectancy, but little is known about whether this is also the case for obsessive-compulsive disorder (OCD). To determine whether persons who receive a diagnosis of OCD are at increased risk of death. Using data from Danish registers, we conducted a nationwide prospective cohort study with 30 million person-years of follow-up. The data were collected from Danish longitudinal registers. A total of 3 million people born between 1955 and 2006 were followed up from January 1, 2002, through December 31, 2011. During this period, 27,236 people died. The data were analyzed primarily in June 2015. We estimated mortality rate ratios (MRRs), adjusted for calendar year, age, sex, maternal and paternal age, place of residence at birth, and somatic comorbidities, to compare persons with OCT with persons without OCD. Of 10,155 persons with OCD (5935 women and 4220 men with a mean [SD] age of 29.1 [11.3] years who contributed a total of 54,937 person-years of observation), 110 (1.1%) died during the average follow-up of 9.7 years. The risk of death by natural or unnatural causes was significantly higher among persons with OCD (MRR, 1.68 [95% CI, 1.31-2.12] for natural causes; MRR, 2.61 [95% CI, 1.91-3.47] for unnatural causes) than among the general population. After the exclusion of persons with comorbid anxiety disorders, depression, or substance use disorders, OCD was still associated with increased mortality risk (MRR, 1.88 [95% CI, 1.27-2.67]). The presence of OCD was associated with a significantly increased mortality risk. Comorbid anxiety disorders, depression, or substance use disorders further increased the risk. However, after adjusting for these and somatic comorbidities, we found that the mortality risk remained significantly increased among persons with OCD.

  1. Mortality Among Persons With Obsessive-Compulsive Disorder in Denmark

    PubMed Central

    Meier, Sandra M.; Mattheisen, Manuel; Mors, Ole; Schendel, Diana E.; Mortensen, Preben B.; Plessen, Kerstin J.

    2016-01-01

    IMPORTANCE Several mental disorders have consistently been found to be associated with decreased life expectancy, but little is known about whether this is also the case for obsessive-compulsive disorder (OCD). OBJECTIVE To determine whether persons who receive a diagnosis of OCD are at increased risk of death. DESIGN, SETTING, AND PARTICIPANTS Using data from Danish registers, we conducted a nationwide prospective cohort study with 30 million person-years of follow-up. The data were collected from Danish longitudinal registers. A total of 3 million people born between 1955 and 2006 were followed up from January 1, 2002, through December 31, 2011. During this period, 27 236 people died. The data were analyzed primarily in June 2015. MAIN OUTCOMES AND MEASURES We estimated mortality rate ratios (MRRs), adjusted for calendar year, age, sex, maternal and paternal age, place of residence at birth, and somatic comorbidities, to compare persons with OCT with persons without OCD. RESULTS Of 10 155 persons with OCD (5935 women and 4220 men with a mean [SD] age of 29.1 [11.3] years who contributed a total of 54 937 person-years of observation), 110 (1.1%) died during the average follow-up of 9.7 years. The risk of death by natural or unnatural causes was significantly higher among persons with OCD (MRR, 1.68 [95% CI, 1.31–2.12] for natural causes; MRR, 2.61 [95% CI, 1.91–3.47] for unnatural causes) than among the general population. After the exclusion of persons with comorbid anxiety disorders, depression, or substance use disorders, OCD was still associated with increased mortality risk (MRR, 1.88 [95% CI, 1.27–2.67]). CONCLUSIONS AND RELEVANCE The presence of OCD was associated with a significantly increased mortality risk. Comorbid anxiety disorders, depression, or substance use disorders further increased the risk. However, after adjusting for these and somatic comorbidities, we found that the mortality risk remained significantly increased among persons with OCD. PMID:26818216

  2. Pre-Finishing of SiC for Optical Applications

    NASA Technical Reports Server (NTRS)

    Rozzi, Jay; Clavier, Odile; Gagne, John

    2011-01-01

    13 Manufacturing & Prototyping A method is based on two unique processing steps that are both based on deterministic machining processes using a single-point diamond turning (SPDT) machine. In the first step, a high-MRR (material removal rate) process is used to machine the part within several microns of the final geometry. In the second step, a low-MRR process is used to machine the part to near optical quality using a novel ductile regime machining (DRM) process. DRM is a deterministic machining process associated with conditions under high hydrostatic pressures and very small depths of cut. Under such conditions, using high negative-rake angle cutting tools, the high-pressure region near the tool corresponds to a plastic zone, where even a brittle material will behave in a ductile manner. In the high-MRR processing step, the objective is to remove material with a sufficiently high rate such that the process is economical, without inducing large-scale subsurface damage. A laser-assisted machining approach was evaluated whereby a CO2 laser was focused in advance of the cutting tool. While CVD (chemical vapor deposition) SiC was successfully machined with this approach, the cutting forces were substantially higher than cuts at room temperature under the same machining conditions. During the experiments, the expansion of the part and the tool due to the heating was carefully accounted for. The higher cutting forces are most likely due to a small reduction in the shear strength of the material compared with a larger increase in friction forces due to the thermal softening effect. The key advantage is that the hybrid machine approach has the potential to achieve optical quality without the need for a separate optical finishing step. Also, this method is scalable, so one can easily progress from machining 50-mm-diameter samples to the 250-mm-diameter mirror that NASA desires.

  3. Measles Vaccination in the Presence or Absence of Maternal Measles Antibody: Impact on Child Survival

    PubMed Central

    Aaby, Peter; Martins, Cesário L.; Garly, May-Lill; Andersen, Andreas; Fisker, Ane B.; Claesson, Mogens H.; Ravn, Henrik; Rodrigues, Amabelia; Whittle, Hilton C.; Benn, Christine S.

    2014-01-01

    Background. Measles vaccine (MV) has a greater effect on child survival when administered in early infancy, when maternal antibody may still be present. Methods. To test whether MV has a greater effect on overall survival if given in the presence of maternal measles antibody, we reanalyzed data from 2 previously published randomized trials of a 2-dose schedule with MV given at 4–6 months and at 9 months of age. In both trials antibody levels had been measured before early measles vaccination. Results. In trial I (1993–1995), the mortality rate was 0.0 per 1000 person-years among children vaccinated with MV in the presence of maternal antibody and 32.3 per 1000 person-years without maternal antibody (mortality rate ratio [MRR], 0.0; 95% confidence interval [CI], 0–.52). In trial II (2003–2007), the mortality rate was 4.2 per 1000 person-years among children vaccinated in presence of maternal measles antibody and 14.5 per 1000 person-years without measles antibody (MRR, 0.29; 95% CI, .09–.91). Possible confounding factors did not explain the difference. In a combined analysis, children who had measles antibody detected when they received their first dose of MV at 4–6 months of age had lower mortality than children with no maternal antibody, the MRR being 0.22 (95% CI, .07–.64) between 4–6 months and 5 years. Conclusions. Child mortality in low-income countries may be reduced by vaccinating against measles in the presence of maternal antibody, using a 2-dose schedule with the first dose at 4–6 months (earlier than currently recommended) and a booster dose at 9–12 months of age. Clinical Trials Registration. NCT00168558. PMID:24829213

  4. Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study.

    PubMed

    Christensen, Steffen; Riis, Anders; Nørgaard, Mette; Sørensen, Henrik T; Thomsen, Reimar W

    2007-04-17

    Mortality after perforated and bleeding peptic ulcer increases with age. Limited data exist on how the higher burden of comorbidity among elderly patients affects this association. We aimed to examine the association of age with short-term mortality after perforated and bleeding peptic ulcer and to determine the impact of comorbidity on this association. In this population-based cohort study in three Danish counties between 1991 and 2003 we identified two cohorts of patients: those hospitalized with a first-time discharge diagnosis of perforated peptic ulcer and those with bleeding peptic ulcer. The diagnoses were ascertained from hospital discharge registries and mortality through the Danish Civil Registration System. Information on comorbidity and use of ulcer-related drugs was obtained through administrative medical databases. We computed age-, gender- and comorbidity-standardized 30-day mortality rates and used Cox's regression to estimate adjusted 30-day mortality rate ratios (MRR) for elderly compared with younger patients. Among 2,061 patients with perforated peptic ulcer, 743 (36%) were 65-79 years old and 513 patients (25%) were aged 80+ years. Standardized 30-day mortality was 8.9% among patients younger than 65 years rising to 44.6% among patients aged 80+ years, corresponding to an adjusted MRR of 5.3 (95% CI: 4.0-7.0). Among 7,232 patients with bleeding peptic ulcer 2,372 (33%) were aged 80+ years. Standardized 30-day mortality among patients younger than 65 was 4.3% compared with 16.9% among patients aged 80+ years, corresponding to an adjusted MRR of 3.7 (95% CI: 2.9-4.7). Analyses stratified by comorbidity consistently showed high MRRs among elderly patients, regardless of comorbidity level. Ageing is a strong predictor for a poor outcome after perforated and bleeding peptic ulcer independently of comorbidity.

  5. Short-term mortality after perforated or bleeding peptic ulcer among elderly patients: a population-based cohort study

    PubMed Central

    2007-01-01

    Background Mortality after perforated and bleeding peptic ulcer increases with age. Limited data exist on how the higher burden of comorbidity among elderly patients affects this association. We aimed to examine the association of age with short-term mortality after perforated and bleeding peptic ulcer and to determine the impact of comorbidity on this association. Methods In this population-based cohort study in three Danish counties between 1991 and 2003 we identified two cohorts of patients: those hospitalized with a first-time discharge diagnosis of perforated peptic ulcer and those with bleeding peptic ulcer. The diagnoses were ascertained from hospital discharge registries and mortality through the Danish Civil Registration System. Information on comorbidity and use of ulcer-related drugs was obtained through administrative medical databases. We computed age-, gender- and comorbidity-standardized 30-day mortality rates and used Cox's regression to estimate adjusted 30-day mortality rate ratios (MRR) for elderly compared with younger patients. Results Among 2,061 patients with perforated peptic ulcer, 743 (36%) were 65–79 years old and 513 patients (25%) were aged 80+ years. Standardized 30-day mortality was 8.9% among patients younger than 65 years rising to 44.6% among patients aged 80+ years, corresponding to an adjusted MRR of 5.3 (95% CI: 4.0–7.0). Among 7,232 patients with bleeding peptic ulcer 2,372 (33%) were aged 80+ years. Standardized 30-day mortality among patients younger than 65 was 4.3% compared with 16.9% among patients aged 80+ years, corresponding to an adjusted MRR of 3.7 (95% CI: 2.9–4.7). Analyses stratified by comorbidity consistently showed high MRRs among elderly patients, regardless of comorbidity level. Conclusion Ageing is a strong predictor for a poor outcome after perforated and bleeding peptic ulcer independently of comorbidity. PMID:17439661

  6. Pricing, Carbon Emission Reduction, Low-Carbon Promotion and Returning Decision in a Closed-Loop Supply Chain under Vertical and Horizontal Cooperation

    PubMed Central

    Li, Hui; Wang, Chuanxu; Shang, Meng; Ou, Wei

    2017-01-01

    In this paper, we examine the influences of vertical and horizontal cooperation models on the optimal decisions and performance of a low-carbon closed-loop supply chain (CLSC) with a manufacturer and two retailers, and study optimal operation in the competitive pricing, competitive the low-carbon promotion, the carbon emission reduction, the used-products collection and the profits. We consider the completely decentralized model, M-R vertical cooperation model, R-R horizontal cooperation model, M-R-R vertical and horizontal cooperation model and completely centralized model, and also identify the optimal decision results and profits. It can be observed from a systematic comparison and numerical analysis that the completely centralized model is best in all optimal decision results among all models. In semi-cooperation, the M-R vertical cooperation model is positive, the R-R horizontal cooperation model is passive, and the positivity of the M-R-R vertical and horizontal cooperation model decreases with competitive intensity increasing in the used-products returning, carbon emissions reduction level, low-carbon promotion effort and the profits of the manufacturer and the entire supply chain. PMID:29104268

  7. Selection of Wire Electrical Discharge Machining Process Parameters on Stainless Steel AISI Grade-304 using Design of Experiments Approach

    NASA Astrophysics Data System (ADS)

    Lingadurai, K.; Nagasivamuni, B.; Muthu Kamatchi, M.; Palavesam, J.

    2012-06-01

    Wire electrical discharge machining (WEDM) is a specialized thermal machining process capable of accurately machining parts of hard materials with complex shapes. Parts having sharp edges that pose difficulties to be machined by the main stream machining processes can be easily machined by WEDM process. Design of Experiments approach (DOE) has been reported in this work for stainless steel AISI grade-304 which is used in cryogenic vessels, evaporators, hospital surgical equipment, marine equipment, fasteners, nuclear vessels, feed water tubing, valves, refrigeration equipment, etc., is machined by WEDM with brass wire electrode. The DOE method is used to formulate the experimental layout, to analyze the effect of each parameter on the machining characteristics, and to predict the optimal choice for each WEDM parameter such as voltage, pulse ON, pulse OFF and wire feed. It is found that these parameters have a significant influence on machining characteristic such as metal removal rate (MRR), kerf width and surface roughness (SR). The analysis of the DOE reveals that, in general the pulse ON time significantly affects the kerf width and the wire feed rate affects SR, while, the input voltage mainly affects the MRR.

  8. Pricing, Carbon Emission Reduction, Low-Carbon Promotion and Returning Decision in a Closed-Loop Supply Chain under Vertical and Horizontal Cooperation.

    PubMed

    Li, Hui; Wang, Chuanxu; Shang, Meng; Ou, Wei

    2017-11-01

    In this paper, we examine the influences of vertical and horizontal cooperation models on the optimal decisions and performance of a low-carbon closed-loop supply chain (CLSC) with a manufacturer and two retailers, and study optimal operation in the competitive pricing, competitive the low-carbon promotion, the carbon emission reduction, the used-products collection and the profits. We consider the completely decentralized model, M-R vertical cooperation model, R-R horizontal cooperation model, M-R-R vertical and horizontal cooperation model and completely centralized model, and also identify the optimal decision results and profits. It can be observed from a systematic comparison and numerical analysis that the completely centralized model is best in all optimal decision results among all models. In semi-cooperation, the M-R vertical cooperation model is positive, the R-R horizontal cooperation model is passive, and the positivity of the M-R-R vertical and horizontal cooperation model decreases with competitive intensity increasing in the used-products returning, carbon emissions reduction level, low-carbon promotion effort and the profits of the manufacturer and the entire supply chain.

  9. Price Analysis on Commercial Item Purchases Within the Department of Defense

    DTIC Science & Technology

    2013-09-01

    KTR contractor MFR memorandum for record MRR market research report PBS Public Building Service SAP simplified acquisition procedures...and reasonable. The survey asked what challenges the respondents face in executing price analysis and in determining and documenting price...organization’s biggest challenge was, a split response was received. Three supervisors answered that the skill level of employees was the biggest challenge

  10. Randomized Trials Comparing Inactivated Vaccine After Medium- or High-titer Measles Vaccine With Standard Titer Measles Vaccine After Inactivated Vaccine: A Meta-analysis.

    PubMed

    Aaby, Peter; Ravn, Henrik; Benn, Christine S; Rodrigues, Amabelia; Samb, Badara; Ibrahim, Salah A; Libman, Michael D; Whittle, Hilton C

    2016-11-01

    Observational studies have suggested that girls have higher mortality if their most recent immunization is an inactivated vaccine rather than a live vaccine. We therefore reanalyzed 5 randomized trials of early measles vaccine (MV) in which it was possible to compare an inactivated vaccines [after medium-titer MV (MTMV) or high-titer MV (HTMV)] and a live standard titer MV (after an initial inactivated vaccine). The trials were conducted in Sudan, Senegal, The Gambia and Guinea-Bissau. The intervention group received live MTMV or HTMV from 4 to 5 months and then an inactivated vaccine from 9 to 10 months of age; the control children received inactivated vaccine/placebo from 4 to 5 months and standard titer MV from 9 to 10 months of age. We compared mortality from 9 months until end of study at 3 to 5 years of age for children who received inactivated vaccine (after MTMV or HTMV) and standard titer MV (after inactivated vaccine), respectively. The original datasets were analyzed using a Cox proportional hazards model stratified by trial. The mortality rate ratio (MRR) was 1.38 (95% confidence interval: 1.05-1.83) after an inactivated vaccine (after MTMV or HTMV) compared with a standard titer MV (after inactivated vaccine). Girls had a MRR of 1.89 (1.27-2.80), whereas there was no effect for boys, the sex-differential effect being significant (P = 0.02). Excluding measles cases did not alter these conclusions, the MRR after inactivated vaccines (after MTMV or HTMV) being 1.40 (1.06-1.86) higher overall and 1.92 (1.29-2.86) for girls. Control for variations in national immunization schedules for other vaccines did not modify these results. After 9 months of age, all children had been immunized against measles, and mortality in girls was higher when they had received inactivated vaccines (after MTMV or HTMV) rather than live standard titer MV (after an inactivated vaccine).

  11. Population Dynamics of Owned, Free-Roaming Dogs: Implications for Rabies Control

    PubMed Central

    Conan, Anne; Akerele, Oluyemisi; Simpson, Greg; Reininghaus, Bjorn; van Rooyen, Jacques; Knobel, Darryn

    2015-01-01

    Background Rabies is a serious yet neglected public health threat in resource-limited communities in Africa, where the virus is maintained in populations of owned, free-roaming domestic dogs. Rabies elimination can be achieved through the mass vaccination of dogs, but maintaining the critical threshold of vaccination coverage for herd immunity in these populations is hampered by their rapid turnover. Knowledge of the population dynamics of free-roaming dog populations can inform effective planning and implementation of mass dog vaccination campaigns to control rabies. Methodology/Principal Findings We implemented a health and demographic surveillance system in dogs that monitored the entire owned dog population within a defined geographic area in a community in Mpumalanga Province, South Africa. We quantified demographic rates over a 24-month period, from 1st January 2012 through 1st January 2014, and assessed their implications for rabies control by simulating the decline in vaccination coverage over time. During this period, the population declined by 10%. Annual population growth rates were +18.6% in 2012 and -24.5% in 2013. Crude annual birth rates (per 1,000 dog-years of observation) were 451 in 2012 and 313 in 2013. Crude annual death rates were 406 in 2012 and 568 in 2013. Females suffered a significantly higher mortality rate in 2013 than males (mortality rate ratio [MRR] = 1.54, 95% CI = 1.28–1.85). In the age class 0–3 months, the mortality rate of dogs vaccinated against rabies was significantly lower than that of unvaccinated dogs (2012: MRR = 0.11, 95% CI = 0.05–0.21; 2013: MRR = 0.31, 95% CI = 0.11–0.69). The results of the simulation showed that achieving a 70% vaccination coverage during annual campaigns would maintain coverage above the critical threshold for at least 12 months. Conclusions and Significance Our findings provide an evidence base for the World Health Organization’s empirically-derived target of 70% vaccination coverage during annual campaigns. Achieving this will be effective even in highly dynamic populations with extremely high growth rates and rapid turnover. This increases confidence in the feasibility of dog rabies elimination in Africa through mass vaccination. PMID:26545242

  12. Tetrachloroethylene Exposure and Bladder Cancer Risk: A Meta-Analysis of Dry-Cleaning-Worker Studies

    PubMed Central

    Vlaanderen, Jelle; Straif, Kurt; Ruder, Avima; Blair, Aaron; Hansen, Johnni; Lynge, Elsebeth; Charbotel, Barbara; Loomis, Dana; Kauppinen, Timo; Kyyronen, Pentti; Pukkala, Eero; Weiderpass, Elisabete

    2014-01-01

    Background: In 2012, the International Agency for Research on Cancer classified tetrachloroethylene, used in the production of chemicals and the primary solvent used in dry cleaning, as “probably carcinogenic to humans” based on limited evidence of an increased risk of bladder cancer in dry cleaners. Objectives: We assessed the epidemiological evidence for the association between tetrachloroethylene exposure and bladder cancer from published studies estimating occupational exposure to tetrachloroethylene or in workers in the dry-cleaning industry. Methods: Random-effects meta-analyses were carried out separately for occupational exposure to tetrachloroethylene and employment as a dry cleaner. We qualitatively summarized exposure–response data because of the limited number of studies available. Results: The meta-relative risk (mRR) among tetrachloroethylene-exposed workers was 1.08 (95% CI: 0.82, 1.42; three studies; 463 exposed cases). For employment as a dry cleaner, the overall mRR was 1.47 (95% CI: 1.16, 1.85; seven studies; 139 exposed cases), and for smoking-adjusted studies, the mRR was 1.50 (95% CI: 0.80, 2.84; 4 case–control studies). Conclusions: Our meta-analysis demonstrates an increased risk of bladder cancer in dry cleaners, reported in both cohort and case–control studies, and some evidence for an exposure–response relationship. Although dry cleaners incur mixed exposures, tetrachloroethylene could be responsible for the excess risk of bladder cancer because it is the primary solvent used and it is the only chemical commonly used by dry cleaners that is currently identified as a potential bladder carcinogen. Relatively crude approaches in exposure assessment in the studies of “tetrachloroethylene-exposed workers” may have attenuated the relative risks. Citation: Vlaanderen J, Straif K, Ruder A, Blair A, Hansen J, Lynge E, Charbotel B, Loomis D, Kauppinen T, Kyyronen P, Pukkala E, Weiderpass E, Guha N. 2014. Tetrachloroethylene exposure and bladder cancer risk: a meta-analysis of dry-cleaning-worker studies. Environ Health Perspect 122:661–666; http://dx.doi.org/10.1289/ehp.1307055 PMID:24659585

  13. [A prospective study to compare the efficiency of oocyte vitrification using closed or open devices].

    PubMed

    Sarandi, S; Herbemont, C; Sermondade, N; Benoit, A; Sonigo, C; Poncelet, C; Benard, J; Gronier, H; Boujenah, J; Grynberg, M; Sifer, C

    2016-05-01

    Oocyte vitrification using an open device is thought to be a source of microbiological and chemical contaminations that can be avoided using a closed device. The principal purpose of this study was to compare the two vitrification protocols: closed and open system. The secondary aim was to study the effects of the storage in the vapor phase of nitrogen (VPN) on oocytes vitrified using an open system and to compare it to those of a storage in liquid nitrogen (LN). Forty-four patients have been included in our study between November 2014 and May 2015. Two hundred and fourteen oocytes have been vitrified at germinal vesicle (GV), metaphase I (0PB) and metaphase II (1PB) stages. We vitrified 96 oocytes (59 GV/37 0PB) using a closed vitrification device and 118 oocytes (57 GV/31 0PB/30 1PB) using an open device. The vitrified oocytes were then stored either in LN or in VPN. The main outcome measures were the survival rate after warming (SR), meiosis resumption rate (MRR) and maturation rate (MR). The global post-thaw SR was significantly higher for oocytes vitrified using an open system (93.2%) compared to those vitrified using a closed one (64.5%; P<0.001). On the contrary, there was no significant difference in terms of global MRR and MR (82.1% vs. 87.5% and 60.7% vs. 61.2% using closed and open system respectively). The SR, MRR and the MR were not significantly different when vitrified oocytes were stored in VPN or LN (91.6, 83.8, 64.5% vs. 93.9, 89.8, 59.1% respectively). Taking into account the limits of our protocol, the open vitrification system remains the more efficient system. The use of sterile liquid nitrogen for oocyte vitrification and the subsequent storage in vapor phase of nitrogen could minimize the hypothetical risks of biological and chemical contaminations. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  14. Intra-urban vulnerability to heat-related mortality in New York City, 1997–2006

    PubMed Central

    Rosenthal, Joyce Klein; Kinney, Patrick L.; Metzger, Kristina B.

    2015-01-01

    The health impacts of exposure to summertime heat are a significant problem in New York City (NYC) and for many cities and are expected to increase with a warming climate. Most studies on heat-related mortality have examined risk factors at the municipal or regional scale and may have missed the intra-urban variation of vulnerability that might inform prevention strategies. We evaluated whether place-based characteristics (socioeconomic/demographic and health factors, as well as the built and biophysical environment) may be associated with greater risk of heat-related mortality for seniors during heat events in NYC. As a measure of relative vulnerability to heat, we used the natural cause mortality rate ratio among those aged 65 and over (MRR65+), comparing extremely hot days (maximum heat index 100 °F+) to all warm season days, across 1997–2006 for NYC's 59 Community Districts and 42 United Hospital Fund neighborhoods. Significant positive associations were found between the MRR65+ and neighborhood-level characteristics: poverty, poor housing conditions, lower rates of access to air-conditioning, impervious land cover, surface temperatures aggregated to the area-level, and seniors’ hypertension. Percent Black/African American and household poverty were strong negative predictors of seniors’ air conditioning access in multivariate regression analysis. PMID:25199872

  15. Effect of photocatalytic oxidation technology on GaN CMP

    NASA Astrophysics Data System (ADS)

    Wang, Jie; Wang, Tongqing; Pan, Guoshun; Lu, Xinchun

    2016-01-01

    GaN is so hard and so chemically inert that it is difficult to obtain a high material removal rate (MRR) in the chemical mechanical polishing (CMP) process. This paper discusses the application of photocatalytic oxidation technology in GaN planarization. Three N-type semiconductor particles (TiO2, SnO2, and Fe2O3) are used as catalysts and added to the H2O2-SiO2-based slurry. By optical excitation, highly reactive photoinduced holes are produced on the surface of the particles, which can oxidize OH- and H2O absorbed on the surface of the catalysts; therefore, more OH* will be generated. As a result, GaN MRRs in an H2O2-SiO2-based polishing system combined with catalysts are improved significantly, especially when using TiO2, the MRR of which is 122 nm/h. The X-ray photoelectron spectroscopy (XPS) analysis shows the variation trend of chemical composition on the GaN surface after polishing, revealing the planarization process. Besides, the effect of pH on photocatalytic oxidation combined with TiO2 is analyzed deeply. Furthermore, the physical model of GaN CMP combined with photocatalytic oxidation technology is proposed to describe the removal mechanism of GaN.

  16. Process optimization for ultrasonic vibration assisted polishing of micro-structured surfaces on super hard material

    NASA Astrophysics Data System (ADS)

    Sun, Zhiyuan; Guo, Bing; Rao, Zhimin; Zhao, Qingliang

    2014-08-01

    In consideration of the excellent property of SiC, the ground micro-structured surface quality is hard to meet the requirement - consequently the ultrasonic vibration assisted polishing (UVAP) of micro-structures of molds is proposed in this paper. Through the orthogonal experiment, the parameters of UVAP of micro-structures were optimized. The experimental results show that, abrasive polishing process, the effect of the workpiece feed rate on the surface roughness (Ra), groove tip radius (R) and material removal rate (MRR) of micro-structures is significant. While, the UVAP, the most significant effect factor for Ra, R and MRR is the ultrasonic amplitude of the ultrasonic vibration. In addition, within the scope of the polishing process parameters selected by preliminary experiments, ultrasonic amplitude of 2.5μm, polishing force of 0.5N, workpiece feed rate of 5 mm·min-1, polishing wheel rotational speed of 50rpm, polishing time of 35min, abrasive size of 100nm and the polishing liquid concentration of 15% is the best technology of UVAP of micro-structures. Under the optimal parameters, the ground traces on the micro-structured surface were removed efficiently and the integrity of the edges of the micro-structure after grinding was maintained efficiently.

  17. Reducing healthy worker survivor bias by restricting date of hire in a cohort study of Vermont granite workers

    PubMed Central

    Applebaum, Katie M; Malloy, Elizabeth J; Eisen, Ellen A

    2007-01-01

    Objective To explore the healthy worker survivor effect (HWSE) in a study of Vermont granite workers by distinguishing “prevalent” from “incident” hires based on date of hire before or after the start of follow‐up. Methods Records of workers between 1950 and 1982 were obtained from a medical surveillance programme. Proportional hazards models were used to model the association between silica exposure and lung cancer mortality, with penalised splines used to smooth the exposure‐response relationship. A sensitivity analysis compared results between the original cohort and subcohorts defined by restricting date of hire to include varying proportions of prevalent hires. Results Restricting to incident hires reduced the 213 cases by 74% and decreased the exposure range. The maximum mortality rate ratio (MRR) was close to twofold in all subcohorts. However, the exposure at which the maximum MRR was achieved decreased from 4.0 to 0.6 mg‐year/m3 as the proportion of prevalent hires decreased from 50% in the original cohort to 0% in the subcohort of incident hires. Conclusion Despite loss in power and restricted exposure range, decreasing the relative proportion of prevalent to incident hires reduced HWSE bias, resulting in stronger evidence for a dose‐response between silica exposure and lung cancer mortality. PMID:17449560

  18. Structural Area Inspection Frequency Evaluation (SAIFE). Volume III. Demonstration Input, Inspection Survey, and MRR Data

    DTIC Science & Technology

    1978-04-01

    3 1.7 Production Rate Change Time . . . . 3 1.8 Time of Fatigue Test Start . ..... 3 1.9 Fatigue Test Acceleration Factor . 3 1.10 Corrosion...simulation logic. SAIFE accounts for the following factors : (1) aircraft design analysis; (2) component and full-scale fatigue testing; (3) production ...reliability; production , servi ce,Information Service, Springfield, and corrosion defects; crack or corrosi on Virginia 22151 detection probability; crack

  19. Network Centric Communications for Expeditionary or Carrier Strike Groups

    DTIC Science & Technology

    2011-12-01

    known as Modulating Retroreflector (MRR) mode. In this configuration, a source laser transmits a beam to an optical receiver which receives the...be adapted for use at sea and found that interference was a key issue. SPAWAR Systems Center Pacific has spent over a decade trying to address this...ad-hoc wireless technology non-proprietary and radio agnostic. One of the issues with wireless technologies used at sea is the issue of ― beam

  20. Preoperative therapy with pazopanib in high-risk soft tissue sarcoma: a phase II window-of-opportunity study by the German Interdisciplinary Sarcoma Group (GISG-04/NOPASS).

    PubMed

    Ronellenfitsch, Ulrich; Dimitrakopoulou-Strauss, Antonia; Jakob, Jens; Kasper, Bernd; Nowak, Kai; Pilz, Lothar R; Attenberger, Ulrike; Gaiser, Timo; Egerer, Gerlinde; Fröhling, Stefan; Derigs, Hans-Günter; Schwarzbach, Matthias; Hohenberger, Peter

    2016-01-06

    For resectable soft tissue sarcoma (STS), radical surgery, usually combined with radiotherapy, is the mainstay of treatment and the only potentially curative modality. Since surgery is often complicated by large tumour size and extensive tumour vasculature, preoperative treatment strategies with the aim of devitalising the tumour are being explored. One option is treatment with antiangiogenic drugs. The multikinase inhibitor pazopanib, which possesses pronounced antiangiogenic effects, has shown activity in metastatic and unresectable STS, but has so far not been tested in the preoperative setting. This open-label, multicentre phase II window-of-opportunity trial assesses pazopanib as preoperative treatment of resectable STS. Participants receive a 21-day course of pazopanib 800 mg daily during wait time for surgery. Major eligibility criteria are resectable, high-risk adult STS of any location, or metachronous solitary STS metastasis for which resection is planned, and adequate organ function and performance status. The trial uses an exact single-stage design. The primary end point is metabolic response rate (MRR), that is, the proportion of patients with >50% reduction of the mean standardised uptake value (SUVmean) in post-treatment compared to pre-treatment fluorodeoxyglucose positron emission tomography CT. The MRR below which the treatment is considered ineffective is 0.2. The MRR above which the treatment warrants further exploration is 0.4. With a type I error of 5% and a power of 80%, the sample size is 35 evaluable patients, with 12 or more responders as threshold. Main secondary end points are histopathological and MRI response, resectability, toxicity, recurrence-free and overall survival. In a translational substudy, endothelial progenitor cells and vascular epithelial growth factor receptor are analysed as potential prognostic and predictive markers. Approval by the ethics committee II, University of Heidelberg, Germany (2012-019F-MA), German Federal Institute for Drugs and Medical Devices (61-3910-4038155) and German Federal Institute for Radiation Protection (Z5-22463/2-2012-007). NCT01543802, EudraCT: 2011-003745-18; Pre-results. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  1. Neighborhood socioeconomic status and the prevalence of stroke and coronary heart disease in rural China: a population-based study

    PubMed Central

    Tang, Xun; Laskowitz, Daniel T.; He, Liu; Østbye, Truls; Bettger, Janet Prvu; Cao, Yang; Li, Na; Li, Jingrong; Zhang, Zongxin; Liu, Jianjiang; Yu, Liping; Xu, Haitao; Hu, Yonghua; Goldstein, Larry B.

    2014-01-01

    Background Lower neighborhood-level socioeconomic status (SES) is associated with an increased risk of vascular disease in developed countries. Aims This study aims to identify village- and individual-level determinants of stroke and coronary heart disease (CHD) in a rural Chinese population. Methods We analyzed data from a population-based survey of 14,424 rural Chinese adults aged over 40-years from 54 villages. Primary outcomes were stroke and CHD prevalence. Village-level SES was determined from the Chinese government's official statistical yearbook. Individual-level characteristics were obtained by in-person interviews. Prevalence rate ratios (RR) and 95% confidence intervals (95% CI) were calculated using generalized linear mixed models with log link function to explore associations of village-level SES and individual social, demographic, and cardiovascular risk factors with stroke or CHD. Variance was expressed using the median rate ratio (MRR) and interval rate ratio (IRR). Results Villages accounted for significant variability in the prevalence of stroke (MRR=1.70; 95% CI:1.42-1.94; P<0.05) and CHD (MRR=1.59; 95% CI:1.35-1.78, P<0.05) with village-level income alone accounted for 10% and 13.5% of between-village variation in stroke and CHD, respectively. High-income villages were at higher risk of both stroke (RR=1.69, 95% CI:1.09∼2.62) and CHD (RR=1.63, 95% CI:1.13∼2.34) than lower-income villages. Among individual-level risk factors, hypertension was associated with a higher prevalence of stroke (RR=2.33, 95% CI:1.93-2.80) than CHD (RR=1.58, 95% CI:1.38-1.82), whereas obesity was only associated with CHD (RR=1.43, 95% CI:1.23-1.66). In addition, there was an interaction between age and income; residents of higher income villages age<60 had a higher prevalence of CHD (RR=1.58, 95% CI:1.15-2.18), but not stroke. Conclusions There were differences in vascular risk across rural villages in China, with higher lifetime stroke and CHD prevalence in higher income villages. For CHD, neighborhood effects were stronger among younger residents of high-income villages. The results may have implications for public health interventions targeting populations at risk. PMID:25088683

  2. observation and analysis of the structure of winter precipitation-generating clouds using ground-based sensor measurements

    NASA Astrophysics Data System (ADS)

    Menéndez José Luis, Marcos; Gómez José Luis, Sánchez; Campano Laura, López; Ortega Eduardo, García; Suances Andrés, Merino; González Sergio, Fernández; Salvador Estíbaliz, Gascón; González Lucía, Hermida

    2015-04-01

    In this study, we used a 28-day database corresponding to December, January and February of 2011/2012 and 2012/2013 campaigns to analyze cloud structure that produced precipitation in the Sierra Norte near Madrid, Spain. We used remote sensing measurements, both active type like the K-band Micro Rain Radar (MRR) and passive type like the Radiometrics MP-3000A multichannel microwave radiometer. Using reflectivity data from the MRR, we determined the important microphysical parameters of Ice Water Content (IWC) and its integrated value over the atmospheric column, or Ice Water Path (IWP). Among the measurements taken by the MP-3000A were Liquid Water Path (LWP) and Integrated Water Vapor (IWV). By representing these data together, sharp declines in LWP and IWV were evident, coincident with IWP increases. This result indicates the ability of a K-band radar to measure the amount of ice in the atmospheric column, simultaneously revealing the Wegener-Bergeron-Findeisen mechanism. We also used a Present Weather Sensor (VPF-730; Biral Ltd., Bristol, UK) to determine the type and amount of precipitation at the surface. With these data, we used regression equations to establish the relationship between visibility and precipitation intensity. In addition, through theoretical precipitation visibility-intensity relationships, we estimated the type of crystal, degree of accretion (riming), and moisture content of fallen snow crystals.

  3. AIBA as Free Radical Initiator for Abrasive-Free Polishing of Hard Disk Substrate

    NASA Astrophysics Data System (ADS)

    Lei, Hong; Ren, Xiaoyan

    2015-04-01

    In order to optimize the existing slurry for abrasive-free polishing (AFP) of a hard disk substrate, a water-soluble free radical initiator, 2,2'-azobis (2-methylpropionamidine) dihydrochloride (AIBA) was introduced into H2O2-based slurry in the present work. Polishing experiment results with AIBA in the H2O2 slurry indicate that the material removal rate (MRR) increases and the polished surface has a lower surface roughness. The mechanism of AIBA in AFP was investigated using electron spin-resonance spectroscopy and UV-Visible analysis, which showed that the concentration of hydroxyl radical (a stronger oxidizer than H2O2) in the slurry was enhanced in the present of AIBA. The structure of the film formed on the substrate surface was investigated by scanning electron microscopy, auger electron spectroscopy and electrochemical impedance spectroscopy technology, showing that a looser and porous oxide film was found on the hard disk substrate surface when treated with the H2O2-AIBA slurry. Furthermore, potentiodynamic polarization tests show that the H2O2-AIBA slurry has a higher corrosion current density, implying that a fast dissolution reaction can occur on the substrate surface. Therefore, we can conclude that the stronger oxidation ability, loose oxide film on the substrate surface, and the higher corrosion-wear rate of the H2O2-AIBA slurry lead to the higher MRR.

  4. A study on the effect of tool electrode thickness on MRR, and TWR in electrical discharge turning process

    NASA Astrophysics Data System (ADS)

    Gohil, Vikas; Puri, YM

    2018-04-01

    Turning by electrical discharge machining (EDM) is an emerging area of research. Generally, wire-EDM is used in EDM turning because it is not concerned with electrode tooling cost. In EDM turning wire electrode leaves cusps on the machined surface because of its small diameters and wire breakage which greatly affect the surface finish of the machined part. Moreover, one of the limitations of the process is low machining speed as compared to constituent processes. In this study, conventional EDM was employed for turning purpose in order to generate free-form cylindrical geometries on difficult-to-cut materials. Therefore, a specially designed turning spindle was mounted on a conventional die-sinking EDM machine to rotate the work piece. A conductive preshaped strip of copper as a forming tool is fed (reciprocate) continuously against the rotating work piece; thus, a mirror image of the tool is formed on the circumference of the work piece. In this way, an axisymmetric work piece can be made with small tools. The developed process is termed as the electrical discharge turning (EDT). In the experiments, the effect of machining parameters, such as pulse-on time, peak current, gap voltage and tool thickness on the MRR, and TWR were investigated and practical machining was carried out by turning of SS-304 stainless steel work piece.

  5. TEA CO2 laser machining of CFRP composite

    NASA Astrophysics Data System (ADS)

    Salama, A.; Li, L.; Mativenga, P.; Whitehead, D.

    2016-05-01

    Carbon fibre-reinforced polymer (CFRP) composites have found wide applications in the aerospace, marine, sports and automotive industries owing to their lightweight and acceptable mechanical properties compared to the commonly used metallic materials. Machining of CFRP composites using lasers can be challenging due to inhomogeneity in the material properties and structures, which can lead to thermal damages during laser processing. In the previous studies, Nd:YAG, diode-pumped solid-state, CO2 (continuous wave), disc and fibre lasers were used in cutting CFRP composites and the control of damages such as the size of heat-affected zones (HAZs) remains a challenge. In this paper, a short-pulsed (8 μs) transversely excited atmospheric pressure CO2 laser was used, for the first time, to machine CFRP composites. The laser has high peak powers (up to 250 kW) and excellent absorption by both the carbon fibre and the epoxy binder. Design of experiment and statistical modelling, based on response surface methodology, was used to understand the interactions between the process parameters such as laser fluence, repetition rate and cutting speed and their effects on the cut quality characteristics including size of HAZ, machining depth and material removal rate (MRR). Based on this study, process parameter optimization was carried out to minimize the HAZ and maximize the MRR. A discussion is given on the potential applications and comparisons to other lasers in machining CFRP.

  6. Increased pulmonary transit times in asymptomatic dogs with mitral regurgitation.

    PubMed

    Lord, Peter; Eriksson, Anders; Häggström, Jens; Järvinen, Anna-Kaisa; Kvart, Clarence; Hansson, Kerstin; Maripuu, Enn; Mäkelä, Olli

    2003-01-01

    Pulmonary transit time (PTT) normalized to heart rate (nPTT) is a measure of the pulmonary blood volume (PBV) to stroke volume ratio (PBV/SV). It is an index of cardiac performance. To determine the effect of compensated mitral regurgitation (CMR) and decompensated mitral regurgitation (DMR) caused by valvular endocardiosis on the index nPTT, we measured nPTT by first-pass radionuclide angiocardiography and ECG in 13 normal dogs, 18 dogs with CMR, and 13 dogs with DMR. PTT was measured as time between onset of appearance of activity at the pulmonary trunk and the left atrium. In the normal dogs, the relationship between PTT and mean R-R interval (mRR) was PTT = 4.08 x mRR + 0.15 (R2 = 0.71). Normal nPTT was 4.4 +/- 0.6 (SD) (range. 3.6-5.3). in CMR, 6.3 +/- 1.6 (SD) (range, 4.0-9.7). and in DMR, 11.9 +/- 3.4 (SD) (range, 8.0-18.8). The differences among all groups were significant. Heart rates were 110 +/- 22 bpm in normal dogs, 111 +/- 20 in dogs with CMR, and 144 +/- 18 in dogs with DMR (P < .001 for difference between DMR group and normal and CMR groups). Increased nPTT in CMR indicates preclinical heart pump dysfunction. Heart rate-normalized pulmonary transit times may be a useful index of heart function in mitral regurgitation.

  7. Dehydrochlorination of 1,1,1-trichloroethane and pentachloroethane by microbially reduced ferruginous smectite.

    PubMed

    Cervini-Silva, Javiera; Kostka, Joel E; Larson, Richard A; Stucki, Joseph W; Wu, Jun

    2003-05-01

    Reduction of structural Fe(III) in smectite clay minerals has been identified as a means to promote dechlorination of polychlorinated ethanes, but its environmental significance has yet to be fully assessed because Fe reduction has normally been achieved by agents uncommon in the environment (e.g., dithionite). This study reports the dehydrochlorination of pentachloroethane and 1,1,1-trichloroethane in the presence of ferruginous smectite reduced by two cultures of microorganisms, Shewanella oneidensis strain MR-1 (MR-R) and an enrichment culture from rice paddy soils (PS-R), in aqueous suspension under anoxic conditions. Microbially reduced ferruginous smectite facilitated dehydrochlorination of 1,1,1-trichloroethane to 1,1-dichloroethene with up to 60% conversion within 3 h of incubation time. In contrast, no formation of 1,1-dichloroethene was observed after incubation of 1,1,1-trichloroethane with chemically reduced ferruginous smectite for 24 h. Microbially reduced ferruginous smectite by MR-R and PS-R promoted the dehydrochlorination of pentachloroethane to tetrachloroethene by 80 and 15%, respectively, after 3 h of incubation time. The conversion of pentachloroethane to tetrachloroethene in the presence of chemically reduced ferruginous smectite after 24 h was 65%. These results indicate that structural Fe(II) in clay minerals has the potential to be an important reductant controlling the fate of organic chemicals in contaminated sediments.

  8. Abrasive Particle Trajectories and Material Removal Non-Uniformity during CMP and Filtration Characteristics of CMP Slurries - A Simulation and Experimental Study

    NASA Astrophysics Data System (ADS)

    Rastegar, Vahid

    Nanoscale finishing and planarization are integral process steps in multilevel metallization designs for integrated circuit (IC) manufacturing since it is necessary to ensure local and global surface planarization at each metal layer before depositing the next layer. Chemical mechanical planarization (CMP) has been widely recognized as the most promising technology to eliminate topographic variation and has allowed the construction of multilevel interconnection structures with a more regularly stacked sequence, resulting in better device performance [1]. Understanding fundamental of the CMP mechanisms can offer guidance to the control and optimization of the polishing processes. CMP kinematics based on slurry distribution and particle trajectories have a significant impact on MRR profiles. In this work a mathematical model to describe particle trajectories during chemical mechanical polishing was developed and extended to account for the effect of larger particles, particle location changes due to slurry dispensing and in-situ conditioning. Material removal rate (MRR) and within wafer non-uniformity (WIWNU) were determined based on the calculated particle trajectory densities. Rotary dynamics and reciprocating motion were optimized to obtain best MRR uniformity. Edge-fast MRR profile was discussed based on mechanical aspect of CMP. Using the model, we also investigated the effect of variable rotational speeds of wafer and pad, and of large particles on WIWNU and scratch growth. It was shown that the presence of even a small portion of large particles can deteriorate the WIWNU significantly and also lead to more scratches. Furthermore, it was shown that the in-situ conditioning improves the uniformity of the polished wafers. Furthermore, a combined experimental and computational study of fibrous filters for removal of larger abrasive particles from aqueous dispersions, essential to minimize defects during chemical mechanical polishing, was performed. Dilute aqueous suspensions of colloidal ceria particles, of known size distribution, were filtered at different flow rates and the filter efficiencies were measured for different particle sizes and pH, then converted to single fiber efficiencies. The particle size distributions were also measured for the influent and effluent streams. In a series of numerical simulations, the Navier-Stokes equation was solved for a single fiber using the ANSYS-FLUENT computational fluid dynamics commercial package. For dilute suspensions, the motion of the dispersed particles in the size range of 35-600 nm and zeta potential range of -50 to 50 mV was tracked in the Lagrangian reference frame including the effects of hydrodynamic drag, lift, gravity, hydrodynamic retardation, Brownian, van der Waals and electric double layer forces. The electric double layer and van der Waals forces were incorporated in the calculations by developing a user defined function. Particular attention was given to the effects of Brownian excitations, as well as the electric double layer and van der Waals forces that have been neglected in many of the previous models on the overall fiber collection efficiency for different particle sizes and charges. Moreover, the effect of flow velocity on the fiber capture efficiency and residence time was investigated. The effect of velocity on minimum collection efficiency and most penetrating particle size was investigated. It was also shown that the CFD results are in a good agreement with the experimental results.

  9. Modeling and Analysis of CNC Milling Process Parameters on Al3030 based Composite

    NASA Astrophysics Data System (ADS)

    Gupta, Anand; Soni, P. K.; Krishna, C. M.

    2018-04-01

    The machining of Al3030 based composites on Computer Numerical Control (CNC) high speed milling machine have assumed importance because of their wide application in aerospace industries, marine industries and automotive industries etc. Industries mainly focus on surface irregularities; material removal rate (MRR) and tool wear rate (TWR) which usually depends on input process parameters namely cutting speed, feed in mm/min, depth of cut and step over ratio. Many researchers have carried out researches in this area but very few have taken step over ratio or radial depth of cut also as one of the input variables. In this research work, the study of characteristics of Al3030 is carried out at high speed CNC milling machine over the speed range of 3000 to 5000 r.p.m. Step over ratio, depth of cut and feed rate are other input variables taken into consideration in this research work. A total nine experiments are conducted according to Taguchi L9 orthogonal array. The machining is carried out on high speed CNC milling machine using flat end mill of diameter 10mm. Flatness, MRR and TWR are taken as output parameters. Flatness has been measured using portable Coordinate Measuring Machine (CMM). Linear regression models have been developed using Minitab 18 software and result are validated by conducting selected additional set of experiments. Selection of input process parameters in order to get best machining outputs is the key contributions of this research work.

  10. Experimental heat and mass transfer of the separated and coupled rotating desiccant wheel and heat wheel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Enteria, Napoleon; Yoshino, Hiroshi; Mochida, Akashi

    The experimental evaluation of the separated and coupled rotating desiccant wheel and heat wheel is reported. The study aims to investigate the performance of the desiccant wheel and of the heat wheel both when operated separately and jointly. The performance evaluation of the desiccant wheel is based on its moisture removal capacity (MRC), moisture removal regeneration (MRR), and moisture mass balance (MMB). In addition, the study used the total energy balance (TEB), sensible coefficient of performance (COP{sub Sensible}), latent coefficient of performance (COP{sub Latent}) and, total coefficient of performance (COP{sub Total}). The performance of the heat wheel is based onmore » its effectiveness. The COP{sub Sensible}, COP{sub Latent} and, COP{sub Total} are used in the performance evaluation of the coupled desiccant wheel and heat wheel. The general results of the study show that the MRC, MRR and MMB coupled with the TEB, COP{sub Latent}, COP{sub Sensible} and COP{sub Total} predict adequately the performance of the desiccant wheel. In addition, the coupled operation of the desiccant wheel and heat wheel, contributed to the reduction of the external thermal energy requirement for the regeneration of the desiccant wheel. This study can be applied in other researches seeking evaluation of the desiccant wheel, heat wheel, and their combined operation. Moreover, the data presented here are significant for the desiccant wheel benchmarking and for evaluation of the desiccant wheel models. (author)« less

  11. 1550 nm modulating retroreflector based on coated nanoparticles for free-space optical communication.

    PubMed

    Rosenkrantz, Etai; Arnon, Shlomi

    2015-06-10

    Nowadays, there is a renaissance in the field of space exploration. Current and future missions depend on astronauts and a swarm of robots for reconnaissance. In order to reduce the power consumption, weight, and size of the robots, an asymmetric communication system may be used. This is achieved by installing modulating retroreflectors (MRRs) on one side of the link and an interrogating laser on the other side. In this paper, we theoretically study an innovative device that can serve as an MRR in the infrared range of the spectrum. The device is based on a ferroelectric PZT thin film containing TiO2 coated Ag nanoparticles, which exhibit strong plasmonic resonance in the infrared range. After intensive analyses, which included calculations and simulations, we were able to design the device to operate at the 1550 nm wavelength. This is of great importance since the design of devices operating at 1550 nm as this wavelength is a mature technology widely used in free-space optics. Hence, this MRR can serve in asymmetric communication links relying on 1550 nm transmissions, which are also eye-safe. To the best of our knowledge, this is the first time coated metal nanoparticles have been proposed to modulate light in the infrared region. The performance of this device is unique, reaching a 17.5 dB modulation contrast with only a ±2 V operating voltage. This modulator may also be used for terrestrial communication such as fiber optics and optical interconnects in future data centers.

  12. Investigations of Effect of Rotary EDM Electrode on Machining Performance of Al6061 Alloy

    NASA Astrophysics Data System (ADS)

    Robinson Smart, D. S.; Jenish Smart, Joses; Periasamy, C.; Ratna Kumar, P. S. Samuel

    2018-04-01

    Electric Discharge Machining is an essential process which is being used for machining desired shape using electrical discharges which creates sparks. There will be electrodes subjected to electric voltage and which are separated by a dielectric liquid. Removing of material will be due to the continuous and rapid current discharges between two electrodes.. The spark is very carefully controlled and localized so that it only affects the surface of the material. Usually in order to prevent the defects which are arising due to the conventional machining, the Electric Discharge Machining (EDM) machining is preferred. Also intricate and complicated shapes can be machined effectively by use of Electric Discharge Machining (EDM). The EDM process usually does not affect the heat treat below the surface. This research work focus on the design and fabrication of rotary EDM tool for machining Al6061alloy and investigation of effect of rotary tool on surface finish, material removal rate and tool wear rate. Also the effect of machining parameters of EDM such as pulse on & off time, current on material Removal Rate (MRR), Surface Roughness (SR) and Electrode wear rate (EWR) have studied. Al6061 alloy can be used for marine and offshore applications by reinforcing some other elements. The investigations have revealed that MRR (material removal rate), surface roughness (Ra) have been improved with the reduction in the tool wear rate (TWR) when the tool is rotating instead of stationary. It was clear that as rotary speed of the tool is increasing the material removal rate is increasing with the reduction of surface finish and tool wear rate.

  13. KDP Aqueous Solution-in-Oil Microemulsion for Ultra-Precision Chemical-Mechanical Polishing of KDP Crystal

    PubMed Central

    Dong, Hui; Wang, Lili; Gao, Wei; Li, Xiaoyuan; Wang, Chao; Ji, Fang; Pan, Jinlong; Wang, Baorui

    2017-01-01

    A novel functional KH2PO4 (KDP) aqueous solution-in-oil (KDP aq/O) microemulsion system for KDP crystal ultra-precision chemical-mechanical polishing (CMP) was prepared. The system, which consisted of decanol, Triton X-100, and KH2PO4 aqueous solution, was available at room temperature. The functional KDP aq/O microemulsion system was systematically studied and applied as polishing solution to KDP CMP technology. In this study, a controlled deliquescent mechanism was proposed for KDP polishing with the KDP aq/O microemulsion. KDP aqueous solution, the chemical etchant in the polishing process, was caged into the micelles in the microemulsion, leading to a limitation of the reaction between the KDP crystal and KDP aqueous solution only if the microemulsion was deformed under the effect of the external force. Based on the interface reaction dynamics, KDP aqueous solutions with different concentrations (cKDP) were applied to replace water in the traditional water-in-oil (W/O) microemulsion. The practicability of the controlled deliquescent mechanism was proved by the decreasing material removal rate (MRR) with the increasing of the cKDP. As a result, the corrosion pits on the KDP surface were avoided to some degree. Moreover, the roughnesses of KDP with KDP aq/O microemulsion (cKDP was changed from 10 mM to 100 mM) as polishing solutions were smaller than that with the W/O microemulsion. The smallest surface root-mean-square roughness of 1.5 nm was obtained at a 30 mmol/L KDP aq solution, because of the most appropriate deliquescent rate and MRR. PMID:28772632

  14. KDP Aqueous Solution-in-Oil Microemulsion for Ultra-Precision Chemical-Mechanical Polishing of KDP Crystal.

    PubMed

    Dong, Hui; Wang, Lili; Gao, Wei; Li, Xiaoyuan; Wang, Chao; Ji, Fang; Pan, Jinlong; Wang, Baorui

    2017-03-09

    A novel functional KH₂PO₄ (KDP) aqueous solution-in-oil (KDP aq/O) microemulsion system for KDP crystal ultra-precision chemical-mechanical polishing (CMP) was prepared. The system, which consisted of decanol, Triton X-100, and KH₂PO₄ aqueous solution, was available at room temperature. The functional KDP aq/O microemulsion system was systematically studied and applied as polishing solution to KDP CMP technology. In this study, a controlled deliquescent mechanism was proposed for KDP polishing with the KDP aq/O microemulsion. KDP aqueous solution, the chemical etchant in the polishing process, was caged into the micelles in the microemulsion, leading to a limitation of the reaction between the KDP crystal and KDP aqueous solution only if the microemulsion was deformed under the effect of the external force. Based on the interface reaction dynamics, KDP aqueous solutions with different concentrations ( c KDP ) were applied to replace water in the traditional water-in-oil (W/O) microemulsion. The practicability of the controlled deliquescent mechanism was proved by the decreasing material removal rate (MRR) with the increasing of the c KDP . As a result, the corrosion pits on the KDP surface were avoided to some degree. Moreover, the roughnesses of KDP with KDP aq/O microemulsion ( c KDP was changed from 10 mM to 100 mM) as polishing solutions were smaller than that with the W/O microemulsion. The smallest surface root-mean-square roughness of 1.5 nm was obtained at a 30 mmol/L KDP aq solution, because of the most appropriate deliquescent rate and MRR.

  15. Enhancing our Understanding of Snowfall Modes with Ground-Based Observations

    NASA Astrophysics Data System (ADS)

    Pettersen, C.; Kulie, M.; Petersen, W. A.; Bliven, L. F.; Wood, N.

    2016-12-01

    Snowfall can be broadly categorized into deep and shallow events based on the vertical distribution of the precipitating ice. Remotely sensed data refine these precipitation categories and aid in discerning the underlying macro- and microphysical mechanisms. The unique patterns in the remotely sensed instruments observations can potentially connect distinct modes of snowfall to specific processes. Though satellites can observe and recognize these patterns in snowfall, these measurements are limited - particularly in cases of shallow and light precipitation, as the snow may be too close to the surface or below the detection limits of the instrumentation. By enhancing satellite measurements with ground-based instrumentation, whether with limited-term field campaigns or long-term strategic sites, we can further our understanding and assumptions about different snowfall modes and how they are measured from spaceborne instruments. Presented are three years of data from a ground-based instrument suite consisting of a MicroRain Radar (MRR; optimized for snow events) and a Precipitation Imaging Package (PIP). These instruments are located at the Marquette, Michigan National Weather Service Weather Forecast Office to: a) use coincident meteorological measurements and observations to enhance our understanding of the thermodynamic drivers and b) showcase these instruments in an operational setting to enhance forecasts of shallow snow events. Three winters of MRR and PIP measurements are partitioned, based on meteorological surface observations, into two-dimensional histograms of reflectivity and particle size distribution data. These statistics improve our interpretation of deep versus shallow precipitation. Additionally, these statistical techniques are applied to similar datasets from Global Precipitation Measurement field campaigns for further insight into cloud and precipitation macro- and microphysical processes.

  16. The relationships between the arrangement of teeth, root resorption, and dental maturity in bovine mandibular incisors

    PubMed Central

    An, Jin-kyu; Ono, Takashi

    2017-01-01

    Objective The objective of this study is to investigate the eruption pattern and root resorption of the bovine anterior dentition in relation to growth-related parameters based on dental maturity. Methods A cross-sectional study was conducted on 110 bovine anterior mandibles by using standard radiography, cone-beam computed tomography (CBCT), and actual measurements. We determined the relationships between the stages of dental maturity by using a modification of Demirjian's method and various growth-related parameters, such as the activity of the root-resorbing tissue and mobility of the deciduous teeth. The correlation of growth-related parameters with interdental spacing and distal unusual root resorption (DRR) of the deciduous fourth incisor was assessed. The cause of mesial unusual root resorption (MRR) of the deciduous fourth incisor was determined on the basis of the arrangement of the permanent third incisor. Results An independent t-test and chi-square test indicated significant differences in growth-related parameters associated with dental arch length discrepancy and factors related to the shedding of deciduous teeth between the low and high dental maturity groups. The samples with interdental spacing and DRR showed a larger sum of mesiodistal permanent crown widths and higher dental maturity than did the respective controls. Samples with MRR tended to show a lingually rotated distal tip of the adjacent tooth crown. Conclusions Dental maturity has relevance to the interdental spaces and unusual root resorption of mixed dentition. The position of the adjacent tooth crown on CBCT may be correlated with the occurrence of unusual root resorption of the incisor. PMID:29090124

  17. Characterizing the physical-basis of orographic rainfall retrieval errors due to terrain artifacts on GPM-DPR reflectivity profiles

    NASA Astrophysics Data System (ADS)

    Arulraj, M.; Barros, A. P.

    2017-12-01

    GPM-DPR reflectivity profiles in mountainous regions are severely handicapped by low level ground-clutter artifacts which have different error characteristics depending on landform (upwind slopes of high mountains versus complex topography in middle-mountains) and precipitation regime. These artifacts result in high detection and estimation errors especially in mid-latitude and tropical mountain regions where low-level light precipitation and complex multi-layer clouds interact with incoming storms. Here, we present results assessment studies in the Southern Appalachian Mountains (SAM) and preliminary results over the eastern slopes of the Andes using ground-based observations from the long-term hydrometeorological networks and model studies toward developing a physically-based framework to systematically identify and attribute measurement errors. Specifically, the focus is on events when GPM-DPR Ka- and Ku- Band precipitation radar misses low-level precipitation with vertical altitude less than 2 km AGL (above ground level). For this purpose, ground-based MRR and Parsivel disdrometer observations near the surface are compared with the reflectivity profiles observed by the GPM-DPR overpasses, the raindrop-size spectra are used to classify the precipitation regime associated with different classes of detection and estimation errors. This information will be used along with a coupled rainfall dynamics and radar simulator model to 1) merge the low-level GPM-DPR measured reflectivity with the MRR reflectivities optimally under strict physically-based constraints and 2) build a library of reflectivity profile corrections. Finally, preliminary 4D analysis of the organization of reflectivity correction modes, microphysical regimes, topography and storm environment will be presented toward developing a general physically-based error model.

  18. Genome Engineering in Bacillus anthracis Using Cre Recombinase

    PubMed Central

    Pomerantsev, Andrei P.; Sitaraman, Ramakrishnan; Galloway, Craig R.; Kivovich, Violetta; Leppla, Stephen H.

    2006-01-01

    Genome engineering is a powerful method for the study of bacterial virulence. With the availability of the complete genomic sequence of Bacillus anthracis, it is now possible to inactivate or delete selected genes of interest. However, many current methods for disrupting or deleting more than one gene require use of multiple antibiotic resistance determinants. In this report we used an approach that temporarily inserts an antibiotic resistance marker into a selected region of the genome and subsequently removes it, leaving the target region (a single gene or a larger genomic segment) permanently mutated. For this purpose, a spectinomycin resistance cassette flanked by bacteriophage P1 loxP sites oriented as direct repeats was inserted within a selected gene. After identification of strains having the spectinomycin cassette inserted by a double-crossover event, a thermo-sensitive plasmid expressing Cre recombinase was introduced at the permissive temperature. Cre recombinase action at the loxP sites excised the spectinomycin marker, leaving a single loxP site within the targeted gene or genomic segment. The Cre-expressing plasmid was then removed by growth at the restrictive temperature. The procedure could then be repeated to mutate additional genes. In this way, we sequentially mutated two pairs of genes: pepM and spo0A, and mcrB and mrr. Furthermore, loxP sites introduced at distant genes could be recombined by Cre recombinase to cause deletion of large intervening regions. In this way, we deleted the capBCAD region of the pXO2 plasmid and the entire 30 kb of chromosomal DNA between the mcrB and mrr genes, and in the latter case we found that the 32 intervening open reading frames were not essential to growth. PMID:16369025

  19. Differences in education and premature mortality: a record linkage study of over 35 million Italians.

    PubMed

    Alicandro, Gianfranco; Frova, Luisa; Sebastiani, Gabriella; Boffetta, Paolo; La Vecchia, Carlo

    2018-04-01

    Large, representative studies are needed to evaluate cause-specific aspects of socio-economic inequalities in mortality. We conducted a census-based retrospective cohort study to quantify differences in cause-specific premature mortality by educational level in Italy. We linked the 2011 Italian census with 2012 and 2013 death registries. We used the mortality rate ratio (MRR) as a measure of relative inequality. Overall, 305 043 deaths (190 061 men-114 982 women) were registered from a population of 35 708 445 subjects aged 30-74. The age-standardized mortality rate for all educational levels was 57.68 deaths per 10 000 person-years among men and 31.41 among women. MRR from all causes was 0.51 (95% CI: 0.49; 0.52) in men and 0.63 (95% CI: 0.61; 0.65) in women for the highest (university) compared to the lowest level of education (none or primary school). The association was stronger in single than in married individuals: MRRs were 0.36 (95% CI: 0.34; 0.39) in single men, 0.57 (95% CI: 0.55; 0.59) in married men, 0.44 (95% CI: 0.40; 0.47) in single women and 0.69 (95% CI: 0.66; 0.72) in married women. High education was associated with lower mortality from liver, circulatory, chronic respiratory and genitourinary diseases in both sexes. Highly educated men had a lower mortality from lung cancer than less educated men, whereas highly educated women did not have a reduced mortality from lung and breast cancers. Level of education is a strong indicator of premature mortality. The magnitude of the association between educational level and mortality differs across sexes, marital status and causes of death.

  20. Evaluation of phytochemical content, antimicrobial, cytotoxic and antitumor activities of extract from Rumex hastatus D. Don roots.

    PubMed

    Sahreen, Sumaira; Khan, Muhammad Rashid; Khan, Rahmat Ali; Hadda, Taibi Ben

    2015-07-03

    Being a part of Chinese as well as ayurdic herbal system, roots of Rumex hastatus D. Don (RH) is highly medicinal, used to regulated blood pressure. It is also reported that the plant is diuretic, laxative, tonic, used against microbial skin diseases, bilious complaints and jaundice. The present study is conducted to evaluate phytochemical, antimicrobial, antitumor and cytotoxic activities of extract obtained from R. hastatus roots. RH roots were powdered and extracted with methanol to get crude extract. Crude extract was further fractioned on the basis of increasing polarity, with n-hexane (HRR), chloroform (CRR), ethyl acetate (ERR), n-butanol (BRR) and residual aqueous fraction (ARR). Methanol extract and its derived fractions were subjected to phytochemical screening and assayed for antibacterial activities via agar well diffusion method. Antifungal activities were checked through agar tube dilution method whereas potato disc assay was employed for the determination of antitumor activity. On the other hand cytotoxic activities were conducted using brine shrimps procedures. The results obtained from phytochemical analysis indicate the presence of alkaloids, anthraquinones, flavonoids and saponins in all the fractions. Most of the plant fractions showed substantial antimicrobial activities, which is in accordance with the spacious use of tested plant samples in primary healthcare center. Fractions of R. hastatus roots for cytotoxicity were tested as an effective cytotoxic was found as BRR > MRR > CRR > ARR > ERR > HRR. Ranking order of fractions of R. hastatus roots for effective antitumor screening was found as MRR > BRR > ARR > CRR > ERR > HRR. These results showed that R. hastatus appeared as an important source for the discovery of new antimicrobial drugs and antitumor agents; verify its traditional uses and its exploitation as therapeutic agent.

  1. Optimally combined regional geoid models for the realization of height systems in developing countries - ORG4heights

    NASA Astrophysics Data System (ADS)

    Lieb, Verena; Schmidt, Michael; Willberg, Martin; Pail, Roland

    2017-04-01

    Precise height systems require high-resolution and high-quality gravity data. However, such data sets are sparse especially in developing or newly industrializing countries. Thus, we initiated the DFG-project "ORG4heights" for the formulation of a general scientific concept how to (1) optimally combine all available data sets and (2) estimate realistic errors. The resulting regional gravity field models then deliver the fundamental basis for (3) establishing physical national height systems. The innovative key aspects of the project incorporate the development of a method which links (low- up to mid-resolution) gravity satellite mission data and (high- down to low-quality) terrestrial data. Hereby, an optimal combination of the data utilizing their highest measure of information including uncertainty quantification and analyzing systematic omission errors is pursued. Regional gravity field modeling via Multi-Resolution Representation (MRR) and Least Squares Collocation (LSC) are studied in detail and compared based on their theoretical fundamentals. From the findings, MRR shall be further developed towards implementing a pyramid algorithm. Within the project, we investigate comprehensive case studies in Saudi Arabia and South America, i. e. regions with varying topography, by means of simulated data with heterogeneous distribution, resolution, quality and altitude. GPS and tide gauge records serve as complementary input or validation data. The resulting products include error propagation, internal and external validation. A generalized concept then is derived in order to establish physical height systems in developing countries. The recommendations may serve as guidelines for sciences and administration. We present the ideas and strategies of the project, which combines methodical development and practical applications with high socio-economic impact.

  2. Heart rate variability (HRV) and muscular system activity (EMG) in cases of crash threat during simulated driving of a passenger car.

    PubMed

    Zużewicz, Krystyna; Roman-Liu, Danuta; Konarska, Maria; Bartuzi, Paweł; Matusiak, Krzysztof; Korczak, Dariusz; Lozia, Zbigniew; Guzek, Marek

    2013-10-01

    The aim of the study was to verify whether simultaneous responses from the muscular and circulatory system occur in the driver's body under simulated conditions of a crash threat. The study was carried out in a passenger car driving simulator. The crash was included in the driving test scenario developed in an urban setting. In the group of 22 young male subjects, two physiological signals - ECG and EMG were continuously recorded. The length of the RR interval in the ECG signal was assessed. A HRV analysis was performed in the time and frequency domains for 1-minute record segments at rest (seated position), during undisturbed driving as well as during and several minutes after the crash. For the left and right side muscles: m. trapezius (TR) and m. flexor digitorum superficialis (FDS), the EMG signal amplitude was determined. The percentage of maximal voluntary contraction (MVC) was compared during driving and during the crash. As for the ECG signal, it was found that in most of the drivers changes occurred in the parameter values reflecting HRV in the time domain. Significant changes were noted in the mean length of RR intervals (mRR). As for the EMG signal, the changes in the amplitude concerned the signal recorded from the FDS muscle. The changes in ECG and EMG were simultaneous in half of the cases. Such parameters as mRR (ECG signal) and FDS-L amplitude (EMG signal) were the responses to accident risk. Under simulated conditions, responses from the circulatory and musculoskeletal systems are not always simultaneous. The results indicate that a more complete driver's response to a crash in road traffic is obtained based on parallel recording of two physiological signals (ECG and EMG).

  3. Long-term follow-up among Danish transfusion recipients identified in the national hepatitis C lookback.

    PubMed

    Just, Søren Andreas; Grau, Katrine; Georgsen, Jørgen; Weis, Nina; Cowan, Susan; Groenbaek, Karin; Krarup, Henrik; Christensen, Peer Brehm

    2012-03-01

    In 1996, a national lookback study was performed in Denmark identifying 1018 patients exposed to hepatitis C virus (HCV) by transfusion before 1991. The objective of this study was to describe morbidity and mortality during extended follow-up among patients in the Danish HCV lookback cohort alive in 1996. In a retrospective cohort study of 230 patients exposed to HCV by blood transfusion and alive in 1996 we extracted data from national registers and compared these with a matched group of unexposed transfusion recipients. Among 230 HCV-exposed recipients alive in 1996, 124 (53.9%) had chronic hepatitis C, 43 (18.7%) were not infected, and 63 (27.4%) had incomplete HCV data. In 2009, 121 (52.6%) were still alive a median of 21.8 years after transfusion. The mortality rate among the HCV-exposed recipients followed from 1996 was 4.9 per 100 person-years (PY). The incidence of liver cirrhosis and decompensated cirrhosis was 1.0 per 100 PY and 0.4 per 100 PY, respectively; 16.5% had cirrhosis at death. Among HCV-exposed recipients, no difference in all-cause or liver-related mortality was observed between HCV-infected and HCV-uninfected recipients. Further, there was no difference in mortality between HCV-exposed and -unexposed transfusion recipients (mortality rate ratio [MRR], 1.06; 95% confidence interval [CI], 0.96-1.17; p = 0.47), but liver-related mortality was significantly higher among HCV-exposed patients (MRR, 10.0; 95% CI, 7.20-17.7; p < 0.001). Two decades after exposure to blood products from HCV-infected donors, only 121(11.8%) of 1018 recipients remained alive. For HCV-exposed recipients no excess all-cause mortality was observed, but liver-related mortality was significantly increased. © 2011 American Association of Blood Banks.

  4. A Multisensor Investigation of Convection During HyMeX SOP1 IOP13

    NASA Technical Reports Server (NTRS)

    Roberto, N.; Adirosi, E.; Baldini, L.; Casella, D.; Dietrich, S.; Panegrossi, G.; Petracca, M.; Sano, P.; Gatlin, P.

    2014-01-01

    A multisensor analysis of the convective precipitation event occurred over Rome during the IOP13 (October 15th, 2012) of the HyMeX (Hydrological cycle in the Mediterranean eXperiment) Special Observation Period (SOP) 1 is presented. Thanks to the cooperation among Italian meteorological services and scientific community and a specific agreement with NASA-GSFC, different types of devices for meteorological measurements were made available during the HyMeX SOP.1. For investigating this event, used are the 3-D lightning data provided by the LINET, the CNR ISAC dual-pol C-band radar (Polar 55C), located in Rome, the Drop Size Distributions (DSD) collected by the 2D Video Disdrometer (2DVD) and the collocated Micro Rain Radar (MRR) installed at the Radio Meteorology Lab. of "Sapienza" University of Rome, located 14 km from the Polar 55C radar. The relation between microphysical structure and electrical activity during the convective phase of the event was investigated using LINET lightning data and Polar 55C (working both in PPI and RHI scanning mode) observations. Location of regions of high horizontal reflectivity (Zh) values ( > 50 dBz), indicating convective precipitation, were found to be associated to a high number of LINET strokes. In addition, an hydrometeor classification scheme applied to the Polar 55C scans was used to detect graupel and to identify a relation between number of LINET strokes and integrated IWC of graupel along the event. Properties of DSDs measured by the 2DVD and vertical DSD profiles estimated by MRR and their relation with the lighting activity registered by LINET were investigated with specific focus on the transition from convective to stratiform regimes. A good agreement was found between convection detected by these instruments and the number of strokes detected by LINET.

  5. The influence of muscle length on the fatigue-related reduction in joint range of motion of the human dorsiflexors.

    PubMed

    Cheng, Arthur J; Davidson, Andrew W; Rice, Charles L

    2010-06-01

    The fatigue-related reduction in joint range of motion (ROM) during dynamic contraction tasks may be related to muscle length-dependent alterations in torque and contractile kinetics, but this has not been systematically explored previously. Twelve young men performed a repetitive voluntary muscle shortening contraction task of the dorsiflexors at a contraction load of 30% of maximum voluntary isometric contraction (MVC) torque, until total 40 degrees ROM had decreased by 50% at task failure (POST) to 20 degrees ROM. At both a short (5 degrees dorsiflexion) and long muscle length (35 degrees plantar flexion joint angle relative to a 0 degrees neutral ankle joint position), voluntary activation, MVC torque, and evoked tibialis anterior contractile properties of a 52.8 Hz high-frequency isometric tetanus [peak evoked torque, maximum rate of torque development (MRTD), maximum rate of relaxation (MRR)] were evaluated at baseline (PRE), at POST, and up to 10 min of recovery. At POST, we measured similar fatigue-related reductions in torque (voluntary and evoked) and slowing of contractile kinetics (MRTD and MRR) at both the short and long muscle lengths. Thus, the fatigue-related reduction in ROM could not be explained by length-dependent fatigue. Although torque (voluntary and evoked) at both muscle lengths was depressed and remained blunted throughout the recovery period, this was not related to the rapid recovery of ROM at 0.5 min after task failure. The reduction in ROM, however, was strongly related to the reduction in joint angular velocity (R(2) = 0.80) during the fatiguing task, although additional factors cannot yet be overlooked.

  6. Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains.

    PubMed

    Popp, Christina; Hampe, Irene A I; Hertlein, Tobias; Ohlsen, Knut; Rogers, P David; Morschhäuser, Joachim

    2017-07-01

    The pathogenic yeast Candida albicans can develop resistance to the widely used antifungal agent fluconazole, which inhibits ergosterol biosynthesis. Resistance is often caused by gain-of-function mutations in the transcription factors Mrr1 and Tac1, which result in constitutive overexpression of multidrug efflux pumps, and Upc2, which result in constitutive overexpression of ergosterol biosynthesis genes. However, the deregulated gene expression that is caused by hyperactive forms of these transcription factors also reduces the fitness of the cells in the absence of the drug. To investigate whether fluconazole-resistant clinical C. albicans isolates have overcome the fitness costs of drug resistance, we assessed the relative fitness of C. albicans isolates containing resistance mutations in these transcription factors in competition with matched drug-susceptible isolates from the same patients. Most of the fluconazole-resistant isolates were outcompeted by the corresponding drug-susceptible isolates when grown in rich medium without fluconazole. On the other hand, some resistant isolates with gain-of-function mutations in MRR1 did not exhibit reduced fitness under these conditions. In a mouse model of disseminated candidiasis, three out of four tested fluconazole-resistant clinical isolates did not exhibit a significant fitness defect. However, all four fluconazole-resistant isolates were outcompeted by the matched susceptible isolates in a mouse model of gastrointestinal colonization, demonstrating that the effects of drug resistance on in vivo fitness depend on the host niche. Collectively, our results indicate that the fitness costs of drug resistance in C. albicans are not easily remediated, especially when proper control of gene expression is required for successful adaptation to life within a mammalian host. Copyright © 2017 American Society for Microbiology.

  7. The impact of comorbid disease history on all-cause and cancer-specific mortality in myeloid leukemia and myeloma - a Swedish population-based study.

    PubMed

    Mohammadi, Mohammad; Cao, Yang; Glimelius, Ingrid; Bottai, Matteo; Eloranta, Sandra; Smedby, Karin E

    2015-11-05

    Comorbidity increases overall mortality in patients diagnosed with hematological malignancies. The impact of comorbidity on cancer-specific mortality, taking competing risks into account, has not been evaluated. Using the Swedish Cancer Register, we identified patients aged >18 years with a first diagnosis of acute myeloid leukemia (AML, N = 2,550), chronic myeloid leukemia (CML, N = 1,000) or myeloma (N = 4,584) 2002-2009. Comorbid disease history was assessed through in- and out-patient care as defined in the Charlson comorbidity index. Mortality rate ratios (MRR) were estimated through 2012 using Poisson regression. Probabilities of cancer-specific death were computed using flexible parametric survival models. Comorbidity was associated with increased all-cause as well as cancer-specific mortality (cancer-specific MRR: AML = 1.27, 95 % CI: 1.15-1.40; CML = 1.28, 0.96-1.70; myeloma = 1.17, 1.08-1.28) compared with patients without comorbidity. Disorders associated with higher cancer-specific mortality were renal disease (in patients with AML, CML and myeloma), cerebrovascular conditions, dementia, psychiatric disease (AML, myeloma), liver and rheumatic disease (AML), cardiovascular and pulmonary disease (myeloma). The difference in the probability of cancer-specific death, comparing patients with and without comorbidity, was largest among AML patients <70 years, whereas in myeloma the difference did not vary by age among the elderly. The probability of cancer-specific death was generally higher than other-cause death even in older age groups, irrespective of comorbidity. Comorbidities associated with organ failure or cognitive function are associated with poorer prognosis in several hematological malignancies, likely due to lower treatment tolerability. The results highlight the need for a better balance between treatment toxicity and efficacy in comorbid and elderly AML, CML and myeloma patients.

  8. Impact of COPD on outcome among patients with complicated peptic ulcer.

    PubMed

    Christensen, Steffen; Thomsen, Reimar W; Tørring, Marie Louise; Riis, Anders; Nørgaard, Mette; Sørensen, Henrik T

    2008-06-01

    COPD is associated with an increased risk of peptic ulcer disease, but limited data exist on whether COPD influences short-term mortality among patients with bleeding and a perforated peptic ulcer. We examined the association between COPD and 30-day mortality following bleeding and perforation of a peptic ulcer. We identified all patients who had been hospitalized with a first-time diagnosis of peptic ulcer perforation (n = 2,033) or bleeding (n = 7,486) in northern Denmark between 1991 and 2004. Information on COPD, comorbidities, and filled prescriptions was obtained from medical databases. Mortality was ascertained using the Danish Civil Registration System. We computed the cumulative 30-day mortality rates for ulcer patients with COPD and for other ulcer patients, and used regression analysis to obtain the 30-day mortality rate ratios (MRRs), controlling for potential confounding factors. Among patients who were hospitalized with perforated peptic ulcers, 218 (10.7%) had previously been hospitalized with COPD. The 30-day mortality rate was 44.0% among perforated ulcer patients with COPD vs 25.5% among other ulcer patients (adjusted MRR, 1.48; 95% confidence interval [CI], 1.18 to 1.85). Among patients hospitalized with a bleeding peptic ulcer, 759 (10.1%) had previously been hospitalized with COPD. The 30-day mortality rate was 16.5% among bleeding peptic ulcer patients with COPD vs 10.8% among other ulcer patients (adjusted MRR, 1.38; 95% CI, 1.14 to 1.68). The use of oral glucocorticoids among COPD patients was associated with higher MRRs for both perforated and bleeding peptic ulcers. COPD substantially increased 30-day mortality among patients with bleeding and perforated peptic ulcers.

  9. Variation in practice patterns in device closure of atrial septal defects and patent ductus arteriosus: An analysis of data from the IMproving Pediatric and Adult Congenital Treatment (IMPACT) registry.

    PubMed

    O'Byrne, Michael L; Kennedy, Kevin F; Rome, Jonathan J; Glatz, Andrew C

    2018-02-01

    Practice variation is a potentially important measure of healthcare quality. The IMPACT registry provides a representative national sample with which to study practice variation in trans-catheter interventions for congenital heart disease. We studied cases for closure of atrial septal defect (ASD) and patent ductus arteriosus (PDA) in IMPACT between January 1, 2011, and September 30, 2015, using hierarchical multivariate models studying (1) the distribution of indications for closure and (2) in patients whose indication for closure was left (LVVO) or right ventricular volume overload (RVVO), the factors influencing probability of closure of a small defect (either in size or in terms of the magnitude of shunt). Over the study period, 5233 PDA and 4459 ASD cases were performed at 77 hospitals. The indications for ASD closure were RVVO in 84% and stroke prevention in 13%. Indications for PDA closure were LVVO in 57%, endocarditis prevention in 36%, and pulmonary hypertension in 7%. There was statistically significant variability in indications between hospitals for PDA and ASD procedures (median rate ratio (MRR): 1.3 and 1.1; both P<.001). The proportion of cases for volume overload with a Qp:Qs <1.5:1 decreased with increasing PDA and ASD procedural volume (P=.04 and 0.05). For ASD, the proportion was higher at hospitals with a larger proportion of adult cases (P=.0007). There was significant variation in practice in the risk of closing PDA <2 mm for LVVO (MRR: 1.4, P<.001). There is measurable variation in transcatheter closure of PDA and ASD. Further research is necessary to study whether this affects outcomes or resource utilization. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Mortality and comorbidities in patients with multiple sclerosis compared with a population without multiple sclerosis: An observational study using the US Department of Defense administrative claims database.

    PubMed

    Capkun, Gorana; Dahlke, Frank; Lahoz, Raquel; Nordstrom, Beth; Tilson, Hugh H; Cutter, Gary; Bischof, Dorina; Moore, Alan; Simeone, Jason; Fraeman, Kathy; Bancken, Fabrice; Geissbühler, Yvonne; Wagner, Michael; Cohan, Stanley

    2015-11-01

    Data are limited for mortality and comorbidities in patients with multiple sclerosis (MS). Compare mortality rates and event rates for comorbidities in MS (n=15,684) and non-MS (n=78,420) cohorts from the US Department of Defense (DoD) database. Comorbidities and all-cause mortality were assessed using the database. Causes of death (CoDs) were assessed through linkage with the National Death Index. Cohorts were compared using mortality (MRR) and event (ERR) rate ratios. All-cause mortality was 2.9-fold higher in the MS versus non-MS cohort (MRR, 95% confidence interval [CI]: 2.9, 2.7-3.2). Frequent CoDs in the MS versus non-MS cohort were infectious diseases (6.2, 4.2-9.4), diseases of the nervous (5.8, 3.7-9.0), respiratory (5.0, 3.9-6.4) and circulatory (2.1, 1.7-2.7) systems and suicide (2.6, 1.3-5.2). Comorbidities including sepsis (ERR, 95% CI: 5.7, 5.1-6.3), ischemic stroke (3.8, 3.5-4.2), attempted suicide (2.4, 1.3-4.5) and ulcerative colitis (2.0, 1.7-2.3), were higher in the MS versus non-MS cohort. The rate of cancers was also higher in the MS versus the non-MS cohort, including lymphoproliferative disorders (2.2, 1.9-2.6) and melanoma (1.7, 1.4-2.0). Rates of mortality and several comorbidities are higher in the MS versus non-MS cohort. Early recognition and management of comorbidities may reduce premature mortality and improve quality of life in patients with MS. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  11. Effects of ruthenium ions on the sensory terminal discharges of the frog muscle spindle.

    PubMed

    Ito, F; Fujitsuka, N; Komatsu, Y

    1983-10-16

    The presence of a mixed Na+-Ca2+ spike along the sensory terminal of the frog muscle spindle was verified. When the terminal was perfused with Ringer's solution containing 0.1-0.5 mM ruthenium red (RuR), the amplitude and duration of the spike were increased, occurring as a prolonged or a long-lasting depolarization of up to 20-30 s duration following individual afferent spikes evoked spontaneously or antidromically by electrical stimulation. In an isotonic TEA solution, the amplitude and duration of the afferent spikes were increased; however, no prolonged depolarization occurred. Adding 0.2 mM RuR to the TEA solution produced the prolonged and long-lasting depolarization. All responses disappeared in the presence of 3 microM TTX or Na+-free Ringer's solution. An impedance decrease along the terminal was observed during the prolonged or long-lasting depolarization. The prolonged depolarization was blocked by the addition of Ca2+-blockers; the afferent spikes remained. In preparations preincubated with 0.1 mM RuR, increasing CaCl2 in Ringer's solution from 0.2 mM, resulted in shortening of the duration of individual spikes with prolonged depolarization and in increase in the maximum rate of rise (MRR) of the spikes. Preincubation with higher concentrations of RuR produced higher sensitivities in the modifications of the duration and MRR to the change in [Ca2+]O. The responses were retained by adding RuR or RuCl3 to Ca2+-free Ringer's solution containing 0.1-5 mM EGTA, although all responses disappeared in Ca2+-free EGTA Ringer's solution. It is concluded that the RuR-induced prolonged response is produced by an influx of Na+.

  12. Seasonal variation in child mortality in rural Guinea-Bissau.

    PubMed

    Nielsen, Bibi Uhre; Byberg, Stine; Aaby, Peter; Rodrigues, Amabelia; Benn, Christine Stabell; Fisker, Ane Baerent

    2017-07-01

    In many African countries, child mortality is higher in the rainy season than in the dry season. We investigated the effect of season on child mortality by time periods, sex and age in rural Guinea-Bissau. Bandim health project follows children under-five in a health and demographic surveillance system in rural Guinea-Bissau. We compared the mortality in the rainy season (June to November) between 1990 and 2013 with the mortality in the dry season (December to May) in Cox proportional hazards models providing rainy vs. dry season mortality rate ratios (r/d-mrr). Seasonal effects were estimated in strata defined by time periods with different frequency of vaccination campaigns, sex and age (<1 month, 1-11 months, 12-59 months). Verbal autopsies were interpreted using InterVa-4 software. From 1990 to 2013, overall mortality was declined by almost two-thirds among 81 292 children (10 588 deaths). Mortality was 51% (95% ci: 45-58%) higher in the rainy season than in the dry season throughout the study period. The seasonal difference increased significantly with age, the r/d-mrr being 0.94 (0.86-1.03) among neonates, 1.57 (1.46-1.69) in post-neonatal infants and 1.83 (1.72-1.95) in under-five children (P for same effect <0.001). According to the InterVa, malaria deaths were the main reason for the seasonal mortality difference, causing 50% of all deaths in the rainy season, but only if the InterVa included season of death, making the argument self-confirmatory. The mortality declined throughout the study, yet rainy season continued to be associated with 51% higher overall mortality. © 2017 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.

  13. Model Robust Calibration: Method and Application to Electronically-Scanned Pressure Transducers

    NASA Technical Reports Server (NTRS)

    Walker, Eric L.; Starnes, B. Alden; Birch, Jeffery B.; Mays, James E.

    2010-01-01

    This article presents the application of a recently developed statistical regression method to the controlled instrument calibration problem. The statistical method of Model Robust Regression (MRR), developed by Mays, Birch, and Starnes, is shown to improve instrument calibration by reducing the reliance of the calibration on a predetermined parametric (e.g. polynomial, exponential, logarithmic) model. This is accomplished by allowing fits from the predetermined parametric model to be augmented by a certain portion of a fit to the residuals from the initial regression using a nonparametric (locally parametric) regression technique. The method is demonstrated for the absolute scale calibration of silicon-based pressure transducers.

  14. The environmental heat flux routine, version 4 (EHFR-4) and Multiple Reflections Routine (MRR), volume 1

    NASA Technical Reports Server (NTRS)

    Dietz, J. B.

    1973-01-01

    The environmental heat flux routine version 4, (EHFR-4) is a generalized computer program which calculates the steady state and/or transient thermal environments experienced by a space system during lunar surface, deep space, or thermal vacuum chamber operation. The specific environments possible for EHFR analysis include: lunar plain, lunar crater, combined lunar plain and crater, lunar plain in the region of spacecraft surfaces, intervehicular, deep space in the region of spacecraft surfaces, and thermal vacuum chamber generation. The EHFR was used for Extra Vehicular Mobility Unit environment analysis of the Apollo 11-17 missions, EMU manned and unmanned thermal vacuum qualification testing, and EMU-LRV interface environmental analyses.

  15. Application of multi response optimization with grey relational analysis and fuzzy logic method

    NASA Astrophysics Data System (ADS)

    Winarni, Sri; Wahyu Indratno, Sapto

    2018-01-01

    Multi-response optimization is an optimization process by considering multiple responses simultaneously. The purpose of this research is to get the optimum point on multi-response optimization process using grey relational analysis and fuzzy logic method. The optimum point is determined from the Fuzzy-GRG (Grey Relational Grade) variable which is the conversion of the Signal to Noise Ratio of the responses involved. The case study used in this research are case optimization of electrical process parameters in electrical disharge machining. It was found that the combination of treatments resulting to optimum MRR and SR was a 70 V gap voltage factor, peak current 9 A and duty factor 0.8.

  16. Complete Genome Sequence of Escherichia coli ER1821R, a Laboratory K-12 Derivative Engineered To Be Deficient in All Methylcytosine and Methyladenine Restriction Systems.

    PubMed

    Jobling, Michael G; Raleigh, Elisabeth A; Frank, Daniel N

    2016-08-11

    We present here the complete genomic sequence of a rifampin-resistant derivative of the Escherichia coli K-12 laboratory strain ER1821, engineered to be deficient in all known restriction systems, making it suitable for generating unbiased libraries from organisms with non-K-12 methylation patterns. The ER1821R genome is most closely related to that of DH1, another popular cloning strain (both derived from MM294), but is deleted for the e14 prophage (McrA(-)) and the immigration control (McrBC(-) EcoKI R(-) M(-) Mrr(-)) loci. Copyright © 2016 Jobling et al.

  17. A comprehensive analysis of the content of heavy rare-earth elements and platinum in snow samples to assess the ecological hazard of air pollution in urban areas

    NASA Astrophysics Data System (ADS)

    Vinokurov, S. F.; Tarasova, N. P.; Trunova, A. N.; Sychkova, V. A.

    2017-07-01

    Snow samples from the territory of the Setun River Valley Wildlife Sanctuary are analyzed for the content of rare-earth elements, heavy metals, and other hazardous elements by the inductively coupled plasma mass-spectrometry method. The changes in the concentrations of rare-earth elements, Pt, Pd, and indicator ratios of elements in the solid fractions of snow are revealed. A trend toward a decrease in the content of several elements northeastward of the Moscow Ring Road (MRR) is established. The level of seasonal atmospheric contamination of the area under study is assessed, and a possible source is identified.

  18. Exposure to styrene and chronic health effects: mortality and incidence of solid cancers in the Danish reinforced plastics industry.

    PubMed Central

    Kolstad, H A; Juel, K; Olsen, J; Lynge, E

    1995-01-01

    OBJECTIVES--To study the occurrence of non-malignant diseases and solid cancers in workers exposed to styrene in the Danish reinforced plastics industry. METHODS--All 36,610 workers of 386 reinforced plastics companies and 14,293 workers not exposed to styrene from similar industries were followed up from 1970 to 1990. This industry is characterised by simple exposure conditions, exposure to high concentrations of styrene, and a high proportion of small companies, and the exposure assessment was based on experts' classification on a company level. The mortality from non-malignant causes and the incidence of solid cancers were compared with the national rates. Poisson models were used for internal comparisons. RESULTS--A total of 3031 deaths and 1134 newly diagnosed cases of solid cancer were reported in the workers in the reinforced plastics industry. In companies where 50% or more of the workers produced reinforced plastics an increased mortality rate ratio (MRR) for degenerative disorders of the nervous system (multiple sclerosis, parkinsonism, and motor neurone disease; MRR 1.8, 16 cases, 95% confidence interval (95% CI) 0.9-3.8) and an increased incidence rate ratio (IRR) for pancreatic cancer (IRR 2.2, 17 cases, 95% CI 1.1-4.5) was found. For both disease categories increased occurrence was also found among long term workers, workers of the 1960s (the period with the highest exposure to styrene), and workers with a latent period of more than 10 years after the start of employment. No other non-malignant diseases or solid cancers showed these patterns. CONCLUSION--The findings have to be interpreted with caution, due to the company based exposure assessment, but the possible association between exposures in the reinforced plastics industry, mainly styrene, and degenerative disorders of the nervous system and pancreatic cancer, deserves attention. PMID:7795754

  19. Influence of electrical resistivity and machining parameters on electrical discharge machining performance of engineering ceramics.

    PubMed

    Ji, Renjie; Liu, Yonghong; Diao, Ruiqiang; Xu, Chenchen; Li, Xiaopeng; Cai, Baoping; Zhang, Yanzhen

    2014-01-01

    Engineering ceramics have been widely used in modern industry for their excellent physical and mechanical properties, and they are difficult to machine owing to their high hardness and brittleness. Electrical discharge machining (EDM) is the appropriate process for machining engineering ceramics provided they are electrically conducting. However, the electrical resistivity of the popular engineering ceramics is higher, and there has been no research on the relationship between the EDM parameters and the electrical resistivity of the engineering ceramics. This paper investigates the effects of the electrical resistivity and EDM parameters such as tool polarity, pulse interval, and electrode material, on the ZnO/Al2O3 ceramic's EDM performance, in terms of the material removal rate (MRR), electrode wear ratio (EWR), and surface roughness (SR). The results show that the electrical resistivity and the EDM parameters have the great influence on the EDM performance. The ZnO/Al2O3 ceramic with the electrical resistivity up to 3410 Ω·cm can be effectively machined by EDM with the copper electrode, the negative tool polarity, and the shorter pulse interval. Under most machining conditions, the MRR increases, and the SR decreases with the decrease of electrical resistivity. Moreover, the tool polarity, and pulse interval affect the EWR, respectively, and the electrical resistivity and electrode material have a combined effect on the EWR. Furthermore, the EDM performance of ZnO/Al2O3 ceramic with the electrical resistivity higher than 687 Ω·cm is obviously different from that with the electrical resistivity lower than 687 Ω·cm, when the electrode material changes. The microstructure character analysis of the machined ZnO/Al2O3 ceramic surface shows that the ZnO/Al2O3 ceramic is removed by melting, evaporation and thermal spalling, and the material from the working fluid and the graphite electrode can transfer to the workpiece surface during electrical discharge machining ZnO/Al2O3 ceramic.

  20. Algorithms for highway-speed acoustic impact-echo evaluation of concrete bridge decks

    NASA Astrophysics Data System (ADS)

    Mazzeo, Brian A.; Guthrie, W. Spencer

    2018-04-01

    A new acoustic impact-echo testing device has been developed for detecting and mapping delaminations in concrete bridge decks at highway speeds. The apparatus produces nearly continuous acoustic excitation of concrete bridge decks through rolling mats of chains that are placed around six wheels mounted to a hinged trailer. The wheels approximately span the width of a traffic lane, and the ability to remotely lower and raise the apparatus using a winch system allows continuous data collection without stationary traffic control or exposure of personnel to traffic. Microphones near the wheels are used to record the acoustic response of the bridge deck during testing. In conjunction with the development of this new apparatus, advances in the algorithms required for data analysis were needed. This paper describes the general framework of the algorithms developed for converting differential global positioning system data and multi-channel audio data into maps that can be used in support of engineering decisions about bridge deck maintenance, rehabilitation, and replacement (MR&R). Acquisition of position and audio data is coordinated on a laptop computer through a custom graphical user interface. All of the streams of data are synchronized with the universal computer time so that audio data can be associated with interpolated position information through data post-processing. The audio segments are individually processed according to particular detection algorithms that can adapt to variations in microphone sensitivity or particular chain excitations. Features that are greater than a predetermined threshold, which is held constant throughout the analysis, are then subjected to further analysis and included in a map that shows the results of the testing. Maps of data collected on a bridge deck using the new acoustic impact-echo testing device at different speeds ranging from approximately 10 km/h to 55 km/h indicate that the collected data are reasonably repeatable. Use of the new acoustic impact-echo testing device is expected to enable more informed decisions about MR&R of concrete bridge decks.

  1. Do cardiometabolic, behavioural and socioeconomic factors explain the 'healthy migrant effect' in the UK? Linked mortality follow-up of South Asians compared with white Europeans in the Newcastle Heart Project.

    PubMed

    Hayes, Louise; White, Martin; McNally, Richard J Q; Unwin, Nigel; Tran, Anh; Bhopal, Raj

    2017-07-25

    Immigrants are sometimes found to have better health than locally born populations. We examined the mortality experience of South Asian origin and white European origin individuals living in Newcastle upon Tyne, UK. A linked 17-21 year mortality follow-up of a cross-sectional study of European (n=825) and South Asian (n=709) men and women, aged 25-74 years, recruited between 1993 and 1997. Poisson regression was used to estimate mortality rate ratios (MRRs) for all-cause mortality. Sensitivity analysis explored the possible effect of differences between ethnic groups in loss to follow-up. The impact of adjustment for established risk factors on MRRs was studied. South Asians had lower all-cause age-adjusted and sex-adjusted mortality than Europeans (MRR 0.70; 95% CI 0.58 to 0.85). There was higher loss to follow-up in South Asians. Sensitivity analyses demonstrated that this did not account for the observed lower mortality. Adjustment for cardiometabolic, behavioural and socioeconomic characteristics attenuated but did not eliminate the mortality differences between South Asians and Europeans, although CIs now cross 1 (MRR 0.79; 95% CI 0.55 to 1.13). South Asians had lower all-cause mortality compared with European origin individuals living in Newcastle upon Tyne that were not accounted for by incomplete mortality data. It is possible that such migrants to the UK have the resources and motivation to move in search of better opportunities and may be healthier and wealthier than those who remain in their country of origin. These findings challenge us to better understand and measure the factors contributing to their survival advantage. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. Co-administration of live measles and yellow fever vaccines and inactivated pentavalent vaccines is associated with increased mortality compared with measles and yellow fever vaccines only. An observational study from Guinea-Bissau.

    PubMed

    Fisker, Ane Bærent; Ravn, Henrik; Rodrigues, Amabelia; Østergaard, Marie Drivsholm; Bale, Carlito; Benn, Christine Stabell; Aaby, Peter

    2014-01-23

    Studies from low-income countries indicate that co-administration of inactivated diphtheria-tetanus-pertussis (DTP) vaccine and live attenuated measles vaccine (MV) is associated with increased mortality compared with receiving MV only. Pentavalent (DTP-H. Influenza type B-Hepatitis B) vaccine is replacing DTP in many low-income countries and yellow fever vaccine (YF) has been introduced to be given together with MV. Pentavalent and YF vaccines were introduced in Guinea-Bissau in 2008. We investigated whether co-administration of pentavalent vaccine with MV and yellow fever vaccine has similar negative effects. In 2007-2011, we conducted a randomised placebo-controlled trial of vitamin A at routine vaccination contacts among children aged 6-23 months in urban and rural Guinea-Bissau. In the present study, we included 2331 children randomised to placebo who received live vaccines only (MV or MV+YF) or a combination of live and inactivated vaccines (MV+DTP or MV+YF+pentavalent). Mortality was compared in Cox proportional hazards models stratified for urban/rural enrolment adjusted for age and unevenly distributed baseline factors. While DTP was still used 685 children received MV only and 358 MV+DTP; following the change in programme, 940 received MV+YF only and 348 MV+YF+pentavalent. During 6 months of follow-up, the adjusted mortality rate ratio (MRR) for co-administered live and inactivated vaccines compared with live vaccines only was 3.24 (1.20-8.73). For MV+YF+pentavalent compared with MV+YF only, the adjusted MRR was 7.73 (1.79-33.4). In line with previous studies of DTP, the present results indicate that pentavalent vaccine co-administered with MV and YF is associated with increased mortality. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Two-channel highly sensitive sensors based on 4 × 4 multimode interference couplers

    NASA Astrophysics Data System (ADS)

    Le, Trung-Thanh

    2017-12-01

    We propose a new kind of microring resonators (MRR) based on 4 × 4 multimode interference (MMI) couplers for multichannel and highly sensitive chemical and biological sensors. The proposed sensor structure has advantages of compactness and high sensitivity compared with the reported sensing structures. By using the transfer matrix method (TMM) and numerical simulations, the designs of the sensor based on silicon waveguides are optimized and demonstrated in detail. We apply our structure to detect glucose and ethanol concentrations simultaneously. A high sensitivity of 9000 nm/RIU, detection limit of 2 × 10‒4 for glucose sensing and sensitivity of 6000 nm/RIU, detection limit of 1.3 × 10‒5 for ethanol sensing are achieved.

  4. Optimisation of wire-cut EDM process parameter by Grey-based response surface methodology

    NASA Astrophysics Data System (ADS)

    Kumar, Amit; Soota, Tarun; Kumar, Jitendra

    2018-03-01

    Wire electric discharge machining (WEDM) is one of the advanced machining processes. Response surface methodology coupled with Grey relation analysis method has been proposed and used to optimise the machining parameters of WEDM. A face centred cubic design is used for conducting experiments on high speed steel (HSS) M2 grade workpiece material. The regression model of significant factors such as pulse-on time, pulse-off time, peak current, and wire feed is considered for optimising the responses variables material removal rate (MRR), surface roughness and Kerf width. The optimal condition of the machining parameter was obtained using the Grey relation grade. ANOVA is applied to determine significance of the input parameters for optimising the Grey relation grade.

  5. Design of CMOS compatible and compact, thermally-compensated electro-optic modulator based on off-axis microring resonator for dense wavelength division multiplexing applications.

    PubMed

    Haldar, Raktim; Banik, Abhik D; Varshney, Shailendra K

    2014-09-22

    In this work, we propose and demonstrate the performance of silicon-on-insulator (SOI) off-axis microring resonator (MRR) as electro-optic modulator (EOM). Adding an extra off-axis inner-ring in conventional microring structure provides control to compensate thermal effects on EOM. It is shown that dynamically controlled bias-voltage applied to the outer ring has the potency to quell the thermal effects over a wide range of temperature. Thus, besides the appositely biased conventional microring, off-axis inner microring with pre-emphasized electrical input message signal enables our proposed structure suitable for high data-rate dense wavelength division multiplexing scheme of optical communication within a very compact device size.

  6. Reducing the uncertainty in robotic machining by modal analysis

    NASA Astrophysics Data System (ADS)

    Alberdi, Iñigo; Pelegay, Jose Angel; Arrazola, Pedro Jose; Ørskov, Klaus Bonde

    2017-10-01

    The use of industrial robots for machining could lead to high cost and energy savings for the manufacturing industry. Machining robots offer several advantages respect to CNC machines such as flexibility, wide working space, adaptability and relatively low cost. However, there are some drawbacks that are preventing a widespread adoption of robotic solutions namely lower stiffness, vibration/chatter problems and lower accuracy and repeatability. Normally due to these issues conservative cutting parameters are chosen, resulting in a low material removal rate (MRR). In this article, an example of a modal analysis of a robot is presented. For that purpose the Tap-testing technology is introduced, which aims at maximizing productivity, reducing the uncertainty in the selection of cutting parameters and offering a stable process free from chatter vibrations.

  7. Optimization of Maghemite (γ-Fe2O3) Nano-Powder Mixed micro-EDM of CoCrMo with Multiple Responses Using Gray Relational Analysis (GRA)

    NASA Astrophysics Data System (ADS)

    Mejid Elsiti, Nagwa; Noordin, M. Y.; Idris, Ani; Saed Majeed, Faraj

    2017-10-01

    This paper presents an optimization of process parameters of Micro-Electrical Discharge Machining (EDM) process with (γ-Fe2O3) nano-powder mixed dielectric using multi-response optimization Grey Relational Analysis (GRA) method instead of single response optimization. These parameters were optimized based on 2-Level factorial design combined with Grey Relational Analysis. The machining parameters such as peak current, gap voltage, and pulse on time were chosen for experimentation. The performance characteristics chosen for this study are material removal rate (MRR), tool wear rate (TWR), Taper and Overcut. Experiments were conducted using electrolyte copper as the tool and CoCrMo as the workpiece. Experimental results have been improved through this approach.

  8. Influence of Electrical Resistivity and Machining Parameters on Electrical Discharge Machining Performance of Engineering Ceramics

    PubMed Central

    Ji, Renjie; Liu, Yonghong; Diao, Ruiqiang; Xu, Chenchen; Li, Xiaopeng; Cai, Baoping; Zhang, Yanzhen

    2014-01-01

    Engineering ceramics have been widely used in modern industry for their excellent physical and mechanical properties, and they are difficult to machine owing to their high hardness and brittleness. Electrical discharge machining (EDM) is the appropriate process for machining engineering ceramics provided they are electrically conducting. However, the electrical resistivity of the popular engineering ceramics is higher, and there has been no research on the relationship between the EDM parameters and the electrical resistivity of the engineering ceramics. This paper investigates the effects of the electrical resistivity and EDM parameters such as tool polarity, pulse interval, and electrode material, on the ZnO/Al2O3 ceramic's EDM performance, in terms of the material removal rate (MRR), electrode wear ratio (EWR), and surface roughness (SR). The results show that the electrical resistivity and the EDM parameters have the great influence on the EDM performance. The ZnO/Al2O3 ceramic with the electrical resistivity up to 3410 Ω·cm can be effectively machined by EDM with the copper electrode, the negative tool polarity, and the shorter pulse interval. Under most machining conditions, the MRR increases, and the SR decreases with the decrease of electrical resistivity. Moreover, the tool polarity, and pulse interval affect the EWR, respectively, and the electrical resistivity and electrode material have a combined effect on the EWR. Furthermore, the EDM performance of ZnO/Al2O3 ceramic with the electrical resistivity higher than 687 Ω·cm is obviously different from that with the electrical resistivity lower than 687 Ω·cm, when the electrode material changes. The microstructure character analysis of the machined ZnO/Al2O3 ceramic surface shows that the ZnO/Al2O3 ceramic is removed by melting, evaporation and thermal spalling, and the material from the working fluid and the graphite electrode can transfer to the workpiece surface during electrical discharge machining ZnO/Al2O3 ceramic. PMID:25364912

  9. Association between Integration Policies and Immigrants’ Mortality: An Explorative Study across Three European Countries

    PubMed Central

    Ikram, Umar Z.; Malmusi, Davide; Juel, Knud; Rey, Grégoire; Kunst, Anton E.

    2015-01-01

    Background To integrate immigrants into their societies, European countries have adopted different types of policies, which may influence health through both material and psychosocial determinants. Recent studies have suggested poorer health outcomes for immigrants living in countries with poorly rated integration policies. Objective To analyse mortality differences of immigrants from the same country of origin living in countries with distinct integration policy contexts. Methods From the mortality dataset collected in the Migrant Ethnic Health Observatory (MEHO) project, we chose the Netherlands (linked data from 1996-2006), France (unlinked; 2005-2007) and Denmark (linked; 1992-2001) as representatives of the inclusive, assimilationist and exclusionist policy models, respectively, based on the Migrant Integration Policy Index. We calculated for each country sex- and age-standardized mortality rates for Turkish-, Moroccan- and local-born populations aged 20-69 years. Poisson regression was used to estimate the mortality rate ratios (MRRs) for cross-country and within-country comparisons. The analyses were further stratified by age group and cause of death. Results Compared with their peers in the Netherlands, Turkish-born immigrants had higher all-cause mortality in Denmark (MRR men 1.92; 95% CI 1.74-2.13 and women 2.11; 1.80-2.47) but lower in France (men 0.64; 0.59-0.69 and women 0.58; 0.51-0.67). A similar pattern emerged for Moroccan-born immigrants. The relative differences between immigrants and the local-born population were also largest in Denmark and lowest in France (e.g., Turkish-born men MRR 1.52; 95% CI 1.38-1.67 and 0.62; 0.58-0.66, respectively). These patterns were consistent across all age groups, and more marked for cardiovascular diseases. Conclusions Although confounders and data comparability issues (e.g., French cross-sectional data) may affect the findings, this study suggests that different macro-level policy contexts may influence immigrants’ mortality. Comparable mortality registration systems across Europe along with detailed socio-demographic information on immigrants may help to better assess this association. PMID:26067249

  10. Compact tunable silicon photonic differential-equation solver for general linear time-invariant systems.

    PubMed

    Wu, Jiayang; Cao, Pan; Hu, Xiaofeng; Jiang, Xinhong; Pan, Ting; Yang, Yuxing; Qiu, Ciyuan; Tremblay, Christine; Su, Yikai

    2014-10-20

    We propose and experimentally demonstrate an all-optical temporal differential-equation solver that can be used to solve ordinary differential equations (ODEs) characterizing general linear time-invariant (LTI) systems. The photonic device implemented by an add-drop microring resonator (MRR) with two tunable interferometric couplers is monolithically integrated on a silicon-on-insulator (SOI) wafer with a compact footprint of ~60 μm × 120 μm. By thermally tuning the phase shifts along the bus arms of the two interferometric couplers, the proposed device is capable of solving first-order ODEs with two variable coefficients. The operation principle is theoretically analyzed, and system testing of solving ODE with tunable coefficients is carried out for 10-Gb/s optical Gaussian-like pulses. The experimental results verify the effectiveness of the fabricated device as a tunable photonic ODE solver.

  11. Experimental realization of a CMOS-compatible optical directed priority encoder using cascaded micro-ring resonators

    NASA Astrophysics Data System (ADS)

    Xiao, Huifu; Li, Dezhao; Liu, Zilong; Han, Xu; Chen, Wenping; Zhao, Ting; Tian, Yonghui; Yang, Jianhong

    2018-03-01

    In this paper, we propose and experimentally demonstrate an integrated optical device that can implement the logical function of priority encoding from a 4-bit electrical signal to a 2-bit optical signal. For the proof of concept, the thermo-optic modulation scheme is adopted to tune each micro-ring resonator (MRR). A monochromatic light with the working wavelength is coupled into the input port of the device through a lensed fiber, and the four input electrical logic signals regarded as pending encode signals are applied to the micro-heaters above four MRRs to control the working states of the optical switches. The encoding results are directed to the output ports in the form of light. At last, the logical function of priority encoding with an operation speed of 10 Kbps is demonstrated successfully.

  12. Query Auto-Completion Based on Word2vec Semantic Similarity

    NASA Astrophysics Data System (ADS)

    Shao, Taihua; Chen, Honghui; Chen, Wanyu

    2018-04-01

    Query auto-completion (QAC) is the first step of information retrieval, which helps users formulate the entire query after inputting only a few prefixes. Regarding the models of QAC, the traditional method ignores the contribution from the semantic relevance between queries. However, similar queries always express extremely similar search intention. In this paper, we propose a hybrid model FS-QAC based on query semantic similarity as well as the query frequency. We choose word2vec method to measure the semantic similarity between intended queries and pre-submitted queries. By combining both features, our experiments show that FS-QAC model improves the performance when predicting the user’s query intention and helping formulate the right query. Our experimental results show that the optimal hybrid model contributes to a 7.54% improvement in terms of MRR against a state-of-the-art baseline using the public AOL query logs.

  13. Effective description of a 3D object for photon transportation in Monte Carlo simulation

    NASA Astrophysics Data System (ADS)

    Suganuma, R.; Ogawa, K.

    2000-06-01

    Photon transport simulation by means of the Monte Carlo method is an indispensable technique for examining scatter and absorption correction methods in SPECT and PET. The authors have developed a method for object description with maximum size regions (maximum rectangular regions: MRRs) to speed up photon transport simulation, and compared the computation time with that for conventional object description methods, a voxel-based (VB) method and an octree method, in the simulations of two kinds of phantoms. The simulation results showed that the computation time with the proposed method became about 50% of that with the VD method and about 70% of that with the octree method for a high resolution MCAT phantom. Here, details of the expansion of the MRR method to three dimensions are given. Moreover, the effectiveness of the proposed method was compared with the VB and octree methods.

  14. Parameter optimization of electrochemical machining process using black hole algorithm

    NASA Astrophysics Data System (ADS)

    Singh, Dinesh; Shukla, Rajkamal

    2017-12-01

    Advanced machining processes are significant as higher accuracy in machined component is required in the manufacturing industries. Parameter optimization of machining processes gives optimum control to achieve the desired goals. In this paper, electrochemical machining (ECM) process is considered to evaluate the performance of the considered process using black hole algorithm (BHA). BHA considers the fundamental idea of a black hole theory and it has less operating parameters to tune. The two performance parameters, material removal rate (MRR) and overcut (OC) are considered separately to get optimum machining parameter settings using BHA. The variations of process parameters with respect to the performance parameters are reported for better and effective understanding of the considered process using single objective at a time. The results obtained using BHA are found better while compared with results of other metaheuristic algorithms, such as, genetic algorithm (GA), artificial bee colony (ABC) and bio-geography based optimization (BBO) attempted by previous researchers.

  15. Optimum surface roughness prediction for titanium alloy by adopting response surface methodology

    NASA Astrophysics Data System (ADS)

    Yang, Aimin; Han, Yang; Pan, Yuhang; Xing, Hongwei; Li, Jinze

    Titanium alloy has been widely applied in industrial engineering products due to its advantages of great corrosion resistance and high specific strength. This paper investigated the processing parameters for finish turning of titanium alloy TC11. Firstly, a three-factor central composite design of experiment, considering the cutting speed, feed rate and depth of cut, are conducted in titanium alloy TC11 and the corresponding surface roughness are obtained. Then a mathematic model is constructed by the response surface methodology to fit the relationship between the process parameters and the surface roughness. The prediction accuracy was verified by the one-way ANOVA. Finally, the contour line of the surface roughness under different combination of process parameters are obtained and used for the optimum surface roughness prediction. Verification experimental results demonstrated that material removal rate (MRR) at the obtained optimum can be significantly improved without sacrificing the surface roughness.

  16. A comparison of neural network architectures for the prediction of MRR in EDM

    NASA Astrophysics Data System (ADS)

    Jena, A. R.; Das, Raja

    2017-11-01

    The aim of the research work is to predict the material removal rate of a work-piece in electrical discharge machining (EDM). Here, an effort has been made to predict the material removal rate through back-propagation neural network (BPN) and radial basis function neural network (RBFN) for a work-piece of AISI D2 steel. The input parameters for the architecture are discharge-current (Ip), pulse-duration (Ton), and duty-cycle (τ) taken for consideration to obtained the output for material removal rate of the work-piece. In the architecture, it has been observed that radial basis function neural network is comparatively faster than back-propagation neural network but logically back-propagation neural network results more real value. Therefore BPN may consider as a better process in this architecture for consistent prediction to save time and money for conducting experiments.

  17. A Review on Parametric Analysis of Magnetic Abrasive Machining Process

    NASA Astrophysics Data System (ADS)

    Khattri, Krishna; Choudhary, Gulshan; Bhuyan, B. K.; Selokar, Ashish

    2018-03-01

    The magnetic abrasive machining (MAM) process is a highly developed unconventional machining process. It is frequently used in manufacturing industries for nanometer range surface finishing of workpiece with the help of Magnetic abrasive particles (MAPs) and magnetic force applied in the machining zone. It is precise and faster than conventional methods and able to produce defect free finished components. This paper provides a comprehensive review on the recent advancement of MAM process carried out by different researcher till date. The effect of different input parameters such as rotational speed of electromagnet, voltage, magnetic flux density, abrasive particles size and working gap on the performances of Material Removal Rate (MRR) and surface roughness (Ra) have been discussed. On the basis of review, it is observed that the rotational speed of electromagnet, voltage and mesh size of abrasive particles have significant impact on MAM process.

  18. Application of a microcomputer-based system to control and monitor bacterial growth.

    PubMed

    Titus, J A; Luli, G W; Dekleva, M L; Strohl, W R

    1984-02-01

    A modular microcomputer-based system was developed to control and monitor various modes of bacterial growth. The control system was composed of an Apple II Plus microcomputer with 64-kilobyte random-access memory; a Cyborg ISAAC model 91A multichannel analog-to-digital and digital-to-analog converter; paired MRR-1 pH, pO(2), and foam control units; and in-house-designed relay, servo control, and turbidimetry systems. To demonstrate the flexibility of the system, we grew bacteria under various computer-controlled and monitored modes of growth, including batch, turbidostat, and chemostat systems. The Apple-ISAAC system was programmed in Labsoft BASIC (extended Applesoft) with an average control program using ca. 6 to 8 kilobytes of memory and up to 30 kilobytes for datum arrays. This modular microcomputer-based control system was easily coupled to laboratory scale fermentors for a variety of fermentations.

  19. Application of a Microcomputer-Based System to Control and Monitor Bacterial Growth

    PubMed Central

    Titus, Jeffrey A.; Luli, Gregory W.; Dekleva, Michael L.; Strohl, William R.

    1984-01-01

    A modular microcomputer-based system was developed to control and monitor various modes of bacterial growth. The control system was composed of an Apple II Plus microcomputer with 64-kilobyte random-access memory; a Cyborg ISAAC model 91A multichannel analog-to-digital and digital-to-analog converter; paired MRR-1 pH, pO2, and foam control units; and in-house-designed relay, servo control, and turbidimetry systems. To demonstrate the flexibility of the system, we grew bacteria under various computer-controlled and monitored modes of growth, including batch, turbidostat, and chemostat systems. The Apple-ISAAC system was programmed in Labsoft BASIC (extended Applesoft) with an average control program using ca. 6 to 8 kilobytes of memory and up to 30 kilobytes for datum arrays. This modular microcomputer-based control system was easily coupled to laboratory scale fermentors for a variety of fermentations. PMID:16346462

  20. Integrated Computer-Aided Manufacturing (ICAM) Architecture. Part 3. Volume 7. MFG01 Glossary.

    DTIC Science & Technology

    1983-09-01

    lat oe C % 000 Sj C4 le ’ 4, 4,4 2:4 tj t*K l- X: 44 0’~ k IW- C4 % 40 Go r 00 c ~ IL P v C c -. . v IL zl - 4 1 S . v I .I a w I 1 v c u > c- -FT U 4...CC c .C C aI o , 0 A Z . 6--c 0 cCrV 46 a .0 b. 1 c 1 . Ga, v 0 M 0 44 c c c f-V - 4 0 aLS C C - . l-l - 2 - 0 S- C (~ b , J O’~ 0 .4. hSV b... ~ b...RD-R144 426 INTEGRATED COMPUTER-AIDED MANUFACTURING (ICAM)_ 1 /3 ARCHITECTURE PART 3 VOLUME.. (U) SOFTECH INC WALTHAM MRR HEINE ET RL. SEP 83 RFWRL-TR

  1. Cyclopentadienyl-containing low-valent early transition metal olefin polymerization catalysts

    DOEpatents

    Marks, Tobin J.; Luo, Lubin; Yoon, Sung Cheol

    2003-04-08

    A catalyst system useful to polymerize and co-polymerize polar and non-polar olefin monomers is formed by in situ reduction with a reducing agent of a catalyst precursor comprising {Cp*MRR'.sub.n }.sup.+ {A}.sup.- wherein Cp* is a cyclopentadienyl or substituted cyclopentadienyl moiety; M is an early transition metal; R is a C.sub.1 -C.sub.20 hydrocarbyl; R' are independently selected from hydride, C.sub.1 -C.sub.20 hydrocarbyl, SiR".sub.3, NR".sub.2, OR", SR", GeR".sub.3, and SnR".sub.3 containing groups (R"=C.sub.1 -C.sub.10 hydrocarbyl); n is an integer selected to balance the oxidation state of M; and A is a suitable non-coordinating anionic cocatalyst or precursor. This catalyst system may form stereoregular olefin polymers including syndiotactic polymers of styrene and methylmethacrylate and isotactic copolymers of polar and nonpolar olefin monomers such as methylmethacrylate and styrene.

  2. Catalytic aided electrical discharge machining of polycrystalline diamond - parameter analysis of finishing condition

    NASA Astrophysics Data System (ADS)

    Haikal Ahmad, M. A.; Zulafif Rahim, M.; Fauzi, M. F. Mohd; Abdullah, Aslam; Omar, Z.; Ding, Songlin; Ismail, A. E.; Rasidi Ibrahim, M.

    2018-01-01

    Polycrystalline diamond (PCD) is regarded as among the hardest material in the world. Electrical Discharge Machining (EDM) typically used to machine this material because of its non-contact process nature. This investigation was purposely done to compare the EDM performances of PCD when using normal electrode of copper (Cu) and newly proposed graphitization catalyst electrode of copper nickel (CuNi). Two level full factorial design of experiment with 4 center points technique was used to study the influence of main and interaction effects of the machining parameter namely; pulse-on, pulse-off, sparking current, and electrode materials (categorical factor). The paper shows interesting discovery in which the newly proposed electrode presented positive impact to the machining performance. With the same machining parameters of finishing, CuNi delivered more than 100% better in Ra and MRR than ordinary Cu electrode.

  3. Characterization of antimicrobial substances produced by Enterococcus faecalis MRR 10-3, isolated from the uropygial gland of the hoopoe (Upupa epops).

    PubMed

    Martín-Platero, Antonio M; Valdivia, Eva; Ruíz-Rodríguez, Magdalena; Soler, Juan J; Martín-Vivaldi, Manuel; Maqueda, Mercedes; Martínez-Bueno, Manuel

    2006-06-01

    The uropygial gland (preen gland) is a holocrine secretory gland situated at the base of the tail in birds which produces a hydrophobic fatty secretion. In certain birds, such as the hoopoe, Upupa epops, the composition of this secretion is influenced by both seasonal and sexual factors, becoming darker and more malodorous in females and in their nestlings during the nesting phase. The secretion is spread throughout the plumage when the bird preens itself, leaving its feathers flexible and waterproof. It is also thought to play a role in defending the bird against predators and parasites. We have isolated from the uropygial secretion of a nestling a bacterium that grows in monospecific culture which we have identified unambiguously by phenotypic and genotypic means as Enterococcus faecalis. The strain in question produces antibacterial substances that are active against all gram-positive bacteria assayed and also against some gram-negative strains. Its peptide nature identifies it as a bacteriocin within the group known as enterocins. Two peptides were purified to homogeneity (MR10A and MR10B), and matrix-assisted laser desorption ionization-time of flight (mass spectrometry) analysis showed masses of 5201.58 and 5207.7 Da, respectively. Amino acid sequencing of both peptides revealed high similarity with enterocin L50A and L50B (L. M. Cintas, P. Casaus, H. Holo, P. E. Hernández, I. F. Nes, and L. S. Håvarstein, J. Bacteriol. 180:1988-1994, 1998). PCR amplification of total DNA from strain MRR10-3 with primers for the L50A/B structural genes and sequencing of the amplified fragment revealed almost identical sequences, except for a single conservative change in residue 38 (Glu-->Asp) in MR10A and two changes in residues 9 (Thr-->Ala) and 15 (Leu-->Phe) in MR10B. This is the first time that the production of bacteriocins by a bacterium isolated from the uropygial gland has been described. The production of these broad-spectrum antibacterial substances by an enterococcal strain living in the uropygial gland may be important to the hygiene of the nest and thus to the health of the eggs and chicks.

  4. Characterization of Antimicrobial Substances Produced by Enterococcus faecalis MRR 10-3, Isolated from the Uropygial Gland of the Hoopoe (Upupa epops)

    PubMed Central

    Martín-Platero, Antonio M.; Valdivia, Eva; Ruíz-Rodríguez, Magdalena; Soler, Juan J.; Martín-Vivaldi, Manuel; Maqueda, Mercedes; Martínez-Bueno, Manuel

    2006-01-01

    The uropygial gland (preen gland) is a holocrine secretory gland situated at the base of the tail in birds which produces a hydrophobic fatty secretion. In certain birds, such as the hoopoe, Upupa epops, the composition of this secretion is influenced by both seasonal and sexual factors, becoming darker and more malodorous in females and in their nestlings during the nesting phase. The secretion is spread throughout the plumage when the bird preens itself, leaving its feathers flexible and waterproof. It is also thought to play a role in defending the bird against predators and parasites. We have isolated from the uropygial secretion of a nestling a bacterium that grows in monospecific culture which we have identified unambiguously by phenotypic and genotypic means as Enterococcus faecalis. The strain in question produces antibacterial substances that are active against all gram-positive bacteria assayed and also against some gram-negative strains. Its peptide nature identifies it as a bacteriocin within the group known as enterocins. Two peptides were purified to homogeneity (MR10A and MR10B), and matrix-assisted laser desorption ionization-time of flight (mass spectrometry) analysis showed masses of 5201.58 and 5207.7 Da, respectively. Amino acid sequencing of both peptides revealed high similarity with enterocin L50A and L50B (L. M. Cintas, P. Casaus, H. Holo, P. E. Hernández, I. F. Nes, and L. S. Håvarstein, J. Bacteriol. 180:1988-1994, 1998). PCR amplification of total DNA from strain MRR10-3 with primers for the L50A/B structural genes and sequencing of the amplified fragment revealed almost identical sequences, except for a single conservative change in residue 38 (Glu→Asp) in MR10A and two changes in residues 9 (Thr→Ala) and 15 (Leu→Phe) in MR10B. This is the first time that the production of bacteriocins by a bacterium isolated from the uropygial gland has been described. The production of these broad-spectrum antibacterial substances by an enterococcal strain living in the uropygial gland may be important to the hygiene of the nest and thus to the health of the eggs and chicks. PMID:16751538

  5. Estimating the snowfall limit in alpine and pre-alpine valleys: A local evaluation of operational approaches

    NASA Astrophysics Data System (ADS)

    Fehlmann, Michael; Gascón, Estíbaliz; Rohrer, Mario; Schwarb, Manfred; Stoffel, Markus

    2018-05-01

    The snowfall limit has important implications for different hazardous processes associated with prolonged or heavy precipitation such as flash floods, rain-on-snow events and freezing precipitation. To increase preparedness and to reduce risk in such situations, early warning systems are frequently used to monitor and predict precipitation events at different temporal and spatial scales. However, in alpine and pre-alpine valleys, the estimation of the snowfall limit remains rather challenging. In this study, we characterize uncertainties related to snowfall limit for different lead times based on local measurements of a vertically pointing micro rain radar (MRR) and a disdrometer in the Zulg valley, Switzerland. Regarding the monitoring, we show that the interpolation of surface temperatures tends to overestimate the altitude of the snowfall limit and can thus lead to highly uncertain estimates of liquid precipitation in the catchment. This bias is much smaller in the Integrated Nowcasting through Comprehensive Analysis (INCA) system, which integrates surface station and remotely sensed data as well as outputs of a numerical weather prediction model. To reduce systematic error, we perform a bias correction based on local MRR measurements and thereby demonstrate the added value of such measurements for the estimation of liquid precipitation in the catchment. Regarding the nowcasting, we show that the INCA system provides good estimates up to 6 h ahead and is thus considered promising for operational hydrological applications. Finally, we explore the medium-range forecasting of precipitation type, especially with respect to rain-on-snow events. We show for a selected case study that the probability for a certain precipitation type in an ensemble-based forecast is more persistent than the respective type in the high-resolution forecast (HRES) of the European Centre for Medium Range Weather Forecasts Integrated Forecasting System (ECMWF IFS). In this case study, the ensemble-based forecast could be used to anticipate such an event up to 7-8 days ahead, whereas the use of the HRES is limited to a lead time of 4-5 days. For the different lead times investigated, we point out possibilities of considering uncertainties in snowfall limit and precipitation type estimates so as to increase preparedness to risk situations.

  6. High-performance, scalable optical network-on-chip architectures

    NASA Astrophysics Data System (ADS)

    Tan, Xianfang

    The rapid advance of technology enables a large number of processing cores to be integrated into a single chip which is called a Chip Multiprocessor (CMP) or a Multiprocessor System-on-Chip (MPSoC) design. The on-chip interconnection network, which is the communication infrastructure for these processing cores, plays a central role in a many-core system. With the continuously increasing complexity of many-core systems, traditional metallic wired electronic networks-on-chip (NoC) became a bottleneck because of the unbearable latency in data transmission and extremely high energy consumption on chip. Optical networks-on-chip (ONoC) has been proposed as a promising alternative paradigm for electronic NoC with the benefits of optical signaling communication such as extremely high bandwidth, negligible latency, and low power consumption. This dissertation focus on the design of high-performance and scalable ONoC architectures and the contributions are highlighted as follow: 1. A micro-ring resonator (MRR)-based Generic Wavelength-routed Optical Router (GWOR) is proposed. A method for developing any sized GWOR is introduced. GWOR is a scalable non-blocking ONoC architecture with simple structure, low cost and high power efficiency compared to existing ONoC designs. 2. To expand the bandwidth and improve the fault tolerance of the GWOR, a redundant GWOR architecture is designed by cascading different type of GWORs into one network. 3. The redundant GWOR built with MRR-based comb switches is proposed. Comb switches can expand the bandwidth while keep the topology of GWOR unchanged by replacing the general MRRs with comb switches. 4. A butterfly fat tree (BFT)-based hybrid optoelectronic NoC (HONoC) architecture is developed in which GWORs are used for global communication and electronic routers are used for local communication. The proposed HONoC uses less numbers of electronic routers and links than its counterpart of electronic BFT-based NoC. It takes the advantages of GWOR in optical communication and BFT in non-uniform traffic communication and three-dimension (3D) implementation. 5. A cycle-accurate NoC simulator is developed to evaluate the performance of proposed HONoC architectures. It is a comprehensive platform that can simulate both electronic and optical NoCs. Different size HONoC architectures are evaluated in terms of throughput, latency and energy dissipation. Simulation results confirm that HONoC achieves good network performance with lower power consumption.

  7. Tunable filters based on an SOI nano-wire waveguide micro ring resonator

    NASA Astrophysics Data System (ADS)

    Shuai, Li; Yuanda, Wu; Xiaojie, Yin; Junming, An; Jianguang, Li; Hongjie, Wang; Xiongwei, Hu

    2011-08-01

    Micro ring resonator (MRR) filters based on a silicon on insulator (SOI) nanowire waveguide are fabricated by electron beam photolithography (EBL) and inductive coupled plasma (ICP) etching technology. The cross-section size of the strip waveguides is 450 × 220 nm2, and the bending radius of the micro ring is around 5 μm. The test results from the tunable filter based on a single ring show that the free spectral range (FSR) is 16.8 nm and the extinction ratio (ER) around the wavelength 1550 nm is 18.1 dB. After thermal tuning, the filter's tuning bandwidth reaches 4.8 nm with a tuning efficiency of 0.12 nm/°C Meanwhile, we fabricated and studied multi-channel filters based on a single ring and a double ring. After measurement, we drew the following conclusions: during the signal transmission of multi-channel filters, crosstalk exists mainly among different transmission channels and are fairly distinct when there are signals input to add ports.

  8. Cyclopentadienyl-containing low-valent early transition metal olefin polymerization catalysts

    DOEpatents

    Marks, Tobin J.; Luo, Lubin; Yoon, Sung Cheol

    2006-10-10

    A catalyst system useful to polymerize and co-polymerize polar and non-polar olefin monomers is formed by in situ reduction with a reducing agent of a catalyst precursor comprising {Cp*MRR'.sub.n}.sup.+{A}.sup.- wherein Cp* is a cyclopentadienyl or substituted cyclopentadienyl moiety; M is an early transition metal; R is a C.sub.1 C.sub.20 hydrocarbyl; R' are independently selected from hydride, C.sub.1 C.sub.20 hydrocarbyl, SiR''.sub.3, NR''.sub.2, OR'', SR'', GeR''.sub.3, SnR''.sub.3, and C.dbd.C-containing groups (R''=C.sub.1 C.sub.10 hydrocarbyl); n is an integer selected to balance the oxidation state of M; and A is a suitable non-coordinating anionic cocatalyst or precursor. This catalyst system may form stereoregular olefin polymers including syndiotactic polymers of styrene and methylmethacrylate and isotactic copolymers of polar and nonpolar olefin monomers such as methylmethacrylate and styrene.

  9. Cyclopentadienyl-containing low-valent early transition metal olefin polymerization catalysts

    DOEpatents

    Marks, Tobin J.; Luo, Lubin; Yoon, Sung Cheol

    2007-01-09

    A catalyst system useful to polymerize and co-polymerize polar and non-polar olefin monomers is formed by in situ reduction with a reducing agent of a catalyst precursor comprising {Cp*MRR'.sub.n}.sup.+{A}.sup.- wherein Cp* is a cyclopentadienyl or substituted cyclopentadienyl moiety; M is an early transition metal; R is a C.sub.1 C.sub.20 hydrocarbyl; R' are independently selected from hydride, C.sub.1 C.sub.20 hydrocarbyl, SiR''.sub.3, NR''.sub.2, OR'', SR'', GeR''.sub.3, SnR''.sub.3, and C.dbd.C-containing groups (R''=C.sub.1 C.sub.10 hydrocarbyl); n is an integer selected to balance the oxidation state of M; and A is a suitable non-coordinating anionic cocatalyst or precursor. This catalyst system may form stereoregular olefin polymers including syndiotactic polymers of styrene and methylmethacrylate and isotactic copolymers of polar and nonpolar olefin monomers such as methylmethacrylate and styrene.

  10. Cyclopentadienyl-Containing Low-Valent Early Transition Metal Olefin Polymerization Catalysts

    DOEpatents

    Marks, Tobin J.; Luo, Lubin; Yoon, Sung Cheol

    2004-06-08

    A catalyst system useful to polymerize and co-polymerize polar and non-polar olefin monomers is formed by in situ reduction with a reducing agent of a catalyst precursor comprising {Cp*MRR'.sub.n }.sup.+ {A}.sup.- wherein Cp* is a cyclopentadienyl or substituted cyclopentadienyl moiety; M is an early transition metal; R is a C.sub.1 -C.sub.20 hydrocarbyl; R' are independently selected from hydride, C.sub.1 -C.sub.20 hydrocarbyl, SiR".sub.3, NR".sub.2, OR", SR", GeR".sub.3, SnR".sub.3, and C.dbd.C-containing groups (R"=C.sub.1 -C.sub.10 hydrocarbyl); n is an integer selected to balance the oxidation state of M; and A is a suitable non-coordinating anionic cocatalyst or precursor. This catalyst system may form stereoregular olefin polymers including syndiotactic polymers of styrene and methylmethacrylate and isotactic copolymers of polar and nonpolar olefin monomers such as methylmethacrylate and styrene.

  11. Broadscale postseismic gravity change following the 2011 Tohoku-Oki earthquake and implication for deformation by viscoelastic relaxation and afterslip

    PubMed Central

    Han, Shin-Chan; Sauber, Jeanne; Pollitz, Fred

    2014-01-01

    The analysis of GRACE gravity data revealed postseismic gravity increase by 6 μGal over a 500 km scale within a couple of years after the 2011 Tohoku-Oki earthquake, which is nearly 40–50% of the coseismic gravity change. It originates mostly from changes in the isotropic component corresponding to the Mrr moment tensor element. The exponential decay with rapid change in a year and gradual change afterward is a characteristic temporal pattern. Both viscoelastic relaxation and afterslip models produce reasonable agreement with the GRACE free-air gravity observation, while their Bouguer gravity patterns and seafloor vertical deformations are distinctly different. The postseismic gravity variation is best modeled by the biviscous relaxation with a transient and steady state viscosity of 1018 and 1019 Pa s, respectively, for the asthenosphere. Our calculated higher-resolution viscoelastic relaxation model, underlying the partially ruptured elastic lithosphere, yields the localized postseismic subsidence above the hypocenter reported from the GPS-acoustic seafloor surveying. PMID:25821272

  12. Intercomparison of attenuation correction algorithms for single-polarized X-band radars

    NASA Astrophysics Data System (ADS)

    Lengfeld, K.; Berenguer, M.; Sempere Torres, D.

    2018-03-01

    Attenuation due to liquid water is one of the largest uncertainties in radar observations. The effects of attenuation are generally inversely proportional to the wavelength, i.e. observations from X-band radars are more affected by attenuation than those from C- or S-band systems. On the other hand, X-band radars can measure precipitation fields in higher temporal and spatial resolution and are more mobile and easier to install due to smaller antennas. A first algorithm for attenuation correction in single-polarized systems was proposed by Hitschfeld and Bordan (1954) (HB), but it gets unstable in case of small errors (e.g. in the radar calibration) and strong attenuation. Therefore, methods have been developed that restrict attenuation correction to keep the algorithm stable, using e.g. surface echoes (for space-borne radars) and mountain returns (for ground radars) as a final value (FV), or adjustment of the radar constant (C) or the coefficient α. In the absence of mountain returns, measurements from C- or S-band radars can be used to constrain the correction. All these methods are based on the statistical relation between reflectivity and specific attenuation. Another way to correct for attenuation in X-band radar observations is to use additional information from less attenuated radar systems, e.g. the ratio between X-band and C- or S-band radar measurements. Lengfeld et al. (2016) proposed such a method based isotonic regression of the ratio between X- and C-band radar observations along the radar beam. This study presents a comparison of the original HB algorithm and three algorithms based on the statistical relation between reflectivity and specific attenuation as well as two methods implementing additional information of C-band radar measurements. Their performance in two precipitation events (one mainly convective and the other one stratiform) shows that a restriction of the HB is necessary to avoid instabilities. A comparison with vertically pointing micro rain radars (MRR) reveals good performance of two of the methods based in the statistical k-Z-relation: FV and α. The C algorithm seems to be more sensitive to differences in calibration of the two systems and requires additional information from C- or S-band radars. Furthermore, a study of five months of radar observations examines the long-term performance of each algorithm. From this study conclusions can be drawn that using additional information from less attenuated radar systems lead to best results. The two algorithms that use this additional information eliminate the bias caused by attenuation and preserve the agreement with MRR observations.

  13. Prediction of the wear and evolution of cutting tools in a carbide / titanium-aluminum-vanadium machining tribosystem by volumetric tool wear characterization and modeling

    NASA Astrophysics Data System (ADS)

    Kuttolamadom, Mathew Abraham

    The objective of this research work is to create a comprehensive microstructural wear mechanism-based predictive model of tool wear in the tungsten carbide / Ti-6Al-4V machining tribosystem, and to develop a new topology characterization method for worn cutting tools in order to validate the model predictions. This is accomplished by blending first principle wear mechanism models using a weighting scheme derived from scanning electron microscopy (SEM) imaging and energy dispersive x-ray spectroscopy (EDS) analysis of tools worn under different operational conditions. In addition, the topology of worn tools is characterized through scanning by white light interferometry (WLI), and then application of an algorithm to stitch and solidify data sets to calculate the volume of the tool worn away. The methodology was to first combine and weight dominant microstructural wear mechanism models, to be able to effectively predict the tool volume worn away. Then, by developing a new metrology method for accurately quantifying the bulk-3D wear, the model-predicted wear was validated against worn tool volumes obtained from corresponding machining experiments. On analyzing worn crater faces using SEM/EDS, adhesion was found dominant at lower surface speeds, while dissolution wear dominated with increasing speeds -- this is in conformance with the lower relative surface speed requirement for micro welds to form and rupture, essentially defining the mechanical load limit of the tool material. It also conforms to the known dominance of high temperature-controlled wear mechanisms with increasing surface speed, which is known to exponentially increase temperatures especially when machining Ti-6Al-4V due to its low thermal conductivity. Thus, straight tungsten carbide wear when machining Ti-6Al-4V is mechanically-driven at low surface speeds and thermally-driven at high surface speeds. Further, at high surface speeds, craters were formed due to carbon diffusing to the tool surface and being carried away by the rubbing action of the chips -- this left behind a smooth crater surface predominantly of tungsten and cobalt as observed from EDS analysis. Also, at high surface speeds, carbon from the tool was found diffused into the adhered titanium layer to form a titanium carbide (TiC) boundary layer -- this was observed as instances of TiC build-up on the tool edge from EDS analysis. A complex wear mechanism interaction was thus observed, i.e., titanium adhered on top of an earlier worn out crater trough, additional carbon diffused into this adhered titanium layer to create a more stable boundary layer (which could limit diffusion-rates on saturation), and then all were further worn away by dissolution wear as temperatures increased. At low and medium feeds, notch discoloration was observed -- this was detected to be carbon from EDS analysis, suggesting that it was deposited from the edges of the passing chips. Mapping the dominant wear mechanisms showed the increasing dominance of dissolution wear relative to adhesion, with increasing grain size -- this is because a 13% larger sub-micron grain results in a larger surface area of cobalt exposed to chemical action. On the macro-scale, wear quantification through topology characterization elevated wear from a 1D to 3D concept. From investigation, a second order dependence of volumetric tool wear (VTW) and VTW rate with the material removal rate (MRR) emerged, suggesting that MRR is a more consistent wear-controlling factor instead of the traditionally used cutting speed. A predictive model for VTW was developed which showed its exponential dependence with workpiece stock volume removed. Also, both VTW and VTW rate were found to be dependent on the accumulated cumulative wear on the tool. Further, a ratio metric of stock material removed to tool volume lost is now possible as a tool efficiency quantifier and energy-based productivity parameter, which was found to inversely depend on MRR - this led to a more comprehensive tool wear definition based on cutting tool efficiency. (Abstract shortened by UMI.)

  14. Experimental Investigation Nano Particles Influence in NPMEDM to Machine Inconel 800 with Electrolyte Copper Electrode

    NASA Astrophysics Data System (ADS)

    Karunakaran, K.; Chandrasekaran, M.

    2017-05-01

    The recent technology of machining hard materials is Powder mix dielectric electrical Discharge Machining (PMEDM). This research investigates nano sized (about 5Nm) powders influence in machining Inconel 800 nickel based super alloy. This work is motivated for a practical need for a manufacturing industry, which processes various kinds of jobs of Inconel 800 material. The conventional EDM machining also considered for investigation for the measure of Nano powders performances. The aluminum, silicon and multi walled Carbon Nano tubes powders were considered in this investigation along with pulse on time, pulse of time and input current to analyze and optimize the responses of Material Removal Rate, Tool Wear Rate and surface roughness. The Taguchi general Full Factorial Design was used to design the experiments. The most advance equipments employed in conducting experiments and measuring equipments to improve the accuracy of the result. The MWCNT powder mix was out performs than other powders which reduce 22% to 50% of the tool wear rate, gives the surface roughness reduction from 29.62% to 41.64% and improved MRR 42.91% to 53.51% than conventional EDM.

  15. Space Optical Communications Using Laser Beam Amplification

    NASA Technical Reports Server (NTRS)

    Agrawal, Govind

    2015-01-01

    The Space Optical Communications Using Laser Beam Amplification (SOCLBA) project will provide a capability to amplify a laser beam that is received in a modulating retro-reflector (MRR) located in a satellite in low Earth orbit. It will also improve the pointing procedure between Earth and spacecraft terminals. The technology uses laser arrays to strengthen the reflected laser beam from the spacecraft. The results of first year's work (2014) show amplification factors of 60 times the power of the signal beam. MMRs are mirrors that reflect light beams back to the source. In space optical communications, a high-powered laser interrogator beam is directed from the ground to a satellite. Within the satellite, the beam is redirected back to ground using the MMR. In the MMR, the beam passes through modulators, which encode a data signal onto the returning beam. MMRs can be used in small spacecraft for optical communications. The SOCLBA project is significant to NASA and small spacecraft due to its application to CubeSats for optical data transmission to ground stations, as well as possible application to spacecraft for optical data transmission.

  16. The Environmental Heat Flux Routine, Version 4 (EHFR-4) and Multiple Reflections Routine (MRR). Volume 2: Programmers reference manual

    NASA Technical Reports Server (NTRS)

    Dietz, J. B.

    1973-01-01

    The EHFR program reference information which is presented consists of the following subprogram detailed data: purpose-description of the routine, a list of the calling programs, an argument list description, nomenclature definition, flow charts, and a compilation listing of each subprogram. Each of the EHFR subprograms were developed specifically for this routine and do not have an applicability of a general nature. Single precision accuracy available on the Univac 1108 is used exclusively in all but two of the 31 EHFR subprograms. The double precision variables required are identified in the nomenclature definition of the two subprograms that require them. A concise definition of the purpose, function, and capabilities is made in the subprogram description. The description references the appropriate Volume 1 sections of the report which contain the applicable detailed definitions, governing equations, and assumptions used. The compilation listing of each subprogram defines the program/data storage requirements, identifies the labeled block common data required, and identifies other subprograms called during execution. For Vol. 1, see N73-31842.

  17. High Sensitivity Detection of Broadband Acoustic Vibration Using Optical Demodulation Method

    NASA Astrophysics Data System (ADS)

    Zhang, Zhen

    Measuring the high frequency acoustic vibrations represents the fundamental interest in revealing the intrinsic dynamic characteristic of board range of systems, such as the growth of the fetus, blood flow in human palms, and vibrations of carbon nanotube. However, the acoustic wave detection capability is limited by the detection bandwidth and sensitivity of the commonly used piezoelectric based ultrasound detectors. To overcome these limitations, this thesis focuses on exploring the optical demodulation method for highly sensitive detection of broadband acoustic vibration. First, a transparent optical ultrasonic detector has been developed using micro-ring resonator (MRR) made of soft polymeric materials. It outperforms the traditional piezoelectric detectors with broader detection bandwidth, miniaturized size and wide angular sensitivity. Its ease of integration into photoacoustic microscopy system has resulted in the great improvement of the imaging resolution. A theoretic framework has been developed to establish the quantitative understanding of its unique distance and angular dependent detection characteristics and was subsequently validated experimentally. The developed theoretic framework provides a guideline to fully accounts for the trade-offs between axial and lateral resolution, working distance, and the field of view in developing optimal imaging performance for a wide range of biological and clinical applications. MRR-based ultrasonic detector is further integrated into confocal fluorescence microscopy to realize the simultaneous imaging of fluorescence and optical absorption of retinal pigment epithelium, achieving multi-contrast imaging at sub-cellular level. The needs to resolve the fine details of the biological specimen with the resolution beyond the diffraction limit further motivate the development of optical demodulated ultrasonic detection method based on near-field scanning optical microscopy (NSOM). The nano-focusing probe was developed for adiabatic focusing of surface plasmon polaritons to the probe apex with high energy efficiency and the suppression of the background noise was accomplished through the implementation of the harmonic demodulation technique. Collectively, this system is capable of delivering intense near-field illumination source while effectively suppressing the background signal due to the far-field scattering and thus, allows for quantitative mapping of local evanescent field with enhanced contrast and improved resolutions. The performance of the developed NSOM system has been validated through the experimental measurements of the surface plasmon polariton mode. This new NSOM system enables optical demodulated ultrasound detection at nanoscale spatial resolution. Using it to detect the ultrasound signal within the acoustic near-field has led to the successful experimental demonstration of the sub-surface photoacoustic imaging of buried objects with sub-diffraction-limited resolution and high sensitivity. Such a new ultrasound detection method holds promising potential for super-resolution ultrasound imaging.

  18. Determination of laser cutting process conditions using the preference selection index method

    NASA Astrophysics Data System (ADS)

    Madić, Miloš; Antucheviciene, Jurgita; Radovanović, Miroslav; Petković, Dušan

    2017-03-01

    Determination of adequate parameter settings for improvement of multiple quality and productivity characteristics at the same time is of great practical importance in laser cutting. This paper discusses the application of the preference selection index (PSI) method for discrete optimization of the CO2 laser cutting of stainless steel. The main motivation for application of the PSI method is that it represents an almost unexplored multi-criteria decision making (MCDM) method, and moreover, this method does not require assessment of the considered criteria relative significances. After reviewing and comparing the existing approaches for determination of laser cutting parameter settings, the application of the PSI method was explained in detail. Experiment realization was conducted by using Taguchi's L27 orthogonal array. Roughness of the cut surface, heat affected zone (HAZ), kerf width and material removal rate (MRR) were considered as optimization criteria. The proposed methodology is found to be very useful in real manufacturing environment since it involves simple calculations which are easy to understand and implement. However, while applying the PSI method it was observed that it can not be useful in situations where there exist a large number of alternatives which have attribute values (performances) very close to those which are preferred.

  19. On-Board Real-Time Optimization Control for Turbo-Fan Engine Life Extending

    NASA Astrophysics Data System (ADS)

    Zheng, Qiangang; Zhang, Haibo; Miao, Lizhen; Sun, Fengyong

    2017-11-01

    A real-time optimization control method is proposed to extend turbo-fan engine service life. This real-time optimization control is based on an on-board engine mode, which is devised by a MRR-LSSVR (multi-input multi-output recursive reduced least squares support vector regression method). To solve the optimization problem, a FSQP (feasible sequential quadratic programming) algorithm is utilized. The thermal mechanical fatigue is taken into account during the optimization process. Furthermore, to describe the engine life decaying, a thermal mechanical fatigue model of engine acceleration process is established. The optimization objective function not only contains the sub-item which can get fast response of the engine, but also concludes the sub-item of the total mechanical strain range which has positive relationship to engine fatigue life. Finally, the simulations of the conventional optimization control which just consider engine acceleration performance or the proposed optimization method have been conducted. The simulations demonstrate that the time of the two control methods from idle to 99.5 % of the maximum power are equal. However, the engine life using the proposed optimization method could be surprisingly increased by 36.17 % compared with that using conventional optimization control.

  20. Multiple performance characteristics optimization for Al 7075 on electric discharge drilling by Taguchi grey relational theory

    NASA Astrophysics Data System (ADS)

    Khanna, Rajesh; Kumar, Anish; Garg, Mohinder Pal; Singh, Ajit; Sharma, Neeraj

    2015-12-01

    Electric discharge drill machine (EDDM) is a spark erosion process to produce micro-holes in conductive materials. This process is widely used in aerospace, medical, dental and automobile industries. As for the performance evaluation of the electric discharge drilling machine, it is very necessary to study the process parameters of machine tool. In this research paper, a brass rod 2 mm diameter was selected as a tool electrode. The experiments generate output responses such as tool wear rate (TWR). The best parameters such as pulse on-time, pulse off-time and water pressure were studied for best machining characteristics. This investigation presents the use of Taguchi approach for better TWR in drilling of Al-7075. A plan of experiments, based on L27 Taguchi design method, was selected for drilling of material. Analysis of variance (ANOVA) shows the percentage contribution of the control factor in the machining of Al-7075 in EDDM. The optimal combination levels and the significant drilling parameters on TWR were obtained. The optimization results showed that the combination of maximum pulse on-time and minimum pulse off-time gives maximum MRR.

  1. Application of grey-fuzzy approach in parametric optimization of EDM process in machining of MDN 300 steel

    NASA Astrophysics Data System (ADS)

    Protim Das, Partha; Gupta, P.; Das, S.; Pradhan, B. B.; Chakraborty, S.

    2018-01-01

    Maraging steel (MDN 300) find its application in many industries as it exhibits high hardness which are very difficult to machine material. Electro discharge machining (EDM) is an extensively popular machining process which can be used in machining of such materials. Optimization of response parameters are essential for effective machining of these materials. Past researchers have already used Taguchi for obtaining the optimal responses of EDM process for this material with responses such as material removal rate (MRR), tool wear rate (TWR), relative wear ratio (RWR), and surface roughness (SR) considering discharge current, pulse on time, pulse off time, arc gap, and duty cycle as process parameters. In this paper, grey relation analysis (GRA) with fuzzy logic is applied to this multi objective optimization problem to check the responses by an implementation of the derived parametric setting. It was found that the parametric setting derived by the proposed method results in better a response than those reported by the past researchers. Obtained results are also verified using the technique for order of preference by similarity to ideal solution (TOPSIS). The predicted result also shows that there is a significant improvement in comparison to the results of past researchers.

  2. Hybrid micromachining using a nanosecond pulsed laser and micro EDM

    NASA Astrophysics Data System (ADS)

    Kim, Sanha; Kim, Bo Hyun; Chung, Do Kwan; Shin, Hong Shik; Chu, Chong Nam

    2010-01-01

    Micro electrical discharge machining (micro EDM) is a well-known precise machining process that achieves micro structures of excellent quality for any conductive material. However, the slow machining speed and high tool wear are main drawbacks of this process. Though the use of deionized water instead of kerosene as a dielectric fluid can reduce the tool wear and increase the machine speed, the material removal rate (MRR) is still low. In contrast, laser ablation using a nanosecond pulsed laser is a fast and non-wear machining process but achieves micro figures of rather low quality. Therefore, the integration of these two processes can overcome the respective disadvantages. This paper reports a hybrid process of a nanosecond pulsed laser and micro EDM for micromachining. A novel hybrid micromachining system that combines the two discrete machining processes is introduced. Then, the feasibility and characteristics of the hybrid machining process are investigated compared to conventional EDM and laser ablation. It is verified experimentally that the machining time can be effectively reduced in both EDM drilling and milling by rapid laser pre-machining prior to micro EDM. Finally, some examples of complicated 3D micro structures fabricated by the hybrid process are shown.

  3. High productivity mould robotic milling in Al-5083

    NASA Astrophysics Data System (ADS)

    Urresti, Iker; Arrazola, Pedro Jose; Ørskov, Klaus Bonde; Pelegay, Jose Angel

    2018-05-01

    Industrial serial robots were usually limited to welding, handling or spray painting operations until very recent years. However, some industries have already realized about their important capabilities in terms of flexibility, working space, adaptability and cost. Hence, currently they are seriously being considered to carry out certain metal machining tasks. Therefore, robot based machining is presented as a cost-saving and flexible manufacturing alternative compared to conventional CNC machines especially for roughing or even pre-roughing of large parts. Nevertheless, there are still some drawbacks usually referred as low rigidity, accuracy and repeatability. Thus, the process productivity is usually sacrificed getting low Material Removal Rates (MRR), and consequently not being competitive. Nevertheless, in this paper different techniques to obtain increased productivity are presented, though an appropriate selection of cutting strategies and parameters that are essential for it. During this research some rough milling tests in Al-5083 are presented where High Feed Milling (HFM) is implemented as productive cutting strategy and the experimental modal analysis named Tap-testing is used for the suitable choice of cutting conditions. Competitive productivity rates are experienced while process stability is checked through the cutting forces measurements in order to prove the effectiveness of the experimental modal analysis for robotic machining.

  4. JPRS Report, Science & Technology, China: Energy.

    DTIC Science & Technology

    1992-03-30

    breeder reactors should become...the primary type of reactors . In developing breeder reactors , we should follow the path of using metal fuel. Breeder reactors give us more time to...first reactor used for power generation was a fast reactor : the " Breeder 1" reactor at the Idaho National Reactor Test Center which was used to

  5. Biofilm reactors for industrial bioconversion processes: employing potential of enhanced reaction rates

    PubMed Central

    Qureshi, Nasib; Annous, Bassam A; Ezeji, Thaddeus C; Karcher, Patrick; Maddox, Ian S

    2005-01-01

    This article describes the use of biofilm reactors for the production of various chemicals by fermentation and wastewater treatment. Biofilm formation is a natural process where microbial cells attach to the support (adsorbent) or form flocs/aggregates (also called granules) without use of chemicals and form thick layers of cells known as "biofilms." As a result of biofilm formation, cell densities in the reactor increase and cell concentrations as high as 74 gL-1 can be achieved. The reactor configurations can be as simple as a batch reactor, continuous stirred tank reactor (CSTR), packed bed reactor (PBR), fluidized bed reactor (FBR), airlift reactor (ALR), upflow anaerobic sludge blanket (UASB) reactor, or any other suitable configuration. In UASB granular biofilm particles are used. This article demonstrates that reactor productivities in these reactors have been superior to any other reactor types. This article describes production of ethanol, butanol, lactic acid, acetic acid/vinegar, succinic acid, and fumaric acid in addition to wastewater treatment in the biofilm reactors. As the title suggests, biofilm reactors have high potential to be employed in biotechnology/bioconversion industry for viable economic reasons. In this article, various reactor types have been compared for the above bioconversion processes. PMID:16122390

  6. Understanding mechanisms behind intense precipitation events in East Antarctica: merging modeling and remote sensing techniques

    NASA Astrophysics Data System (ADS)

    Gorodetskaya, Irina V.; Maahn, Maximilian; Gallée, Hubert; Kneifel, Stefan; Souverijns, Niels; Gossart, Alexandra; Crewell, Susanne; Van Lipzig, Nicole P. M.

    2016-04-01

    Large interannual variability has been found in surface mass balance (SMB) over the East Antarctic ice sheet coastal and escarpment zones, with the total yearly SMB strongly depending on occasional intense precipitation events. Thus for correct prediction of the ice sheet climate and SMB, climate models should be capable to represent such events. Not less importantly, models should also correctly represent the relevant mechanisms behind. The coupled land-atmosphere non-hydrostatic regional climate model MAR (Modèle Atmosphérique Régional) is used to simulate climate and SMB of Dronning Maud Land (DML), East Antarctica. DML has shown a significant increase in SMB during the last years attributed to only few occasional very intense snowfall events. MAR is run at 5km horizontal resolution using initial and boundary conditions from the European Centre for Medium-range Weather Forecasts (ECMWF) Interim re-analysis atmospheric and oceanic fields. The MAR microphysical scheme predicts the evolution of the mixing ratios of five water species: specific humidity, cloud droplets and ice crystals, raindrops and snow particles. Additional prognostic equation describes the number concentration of cloud ice crystals. The mass and terminal velocity of snow particles are defined as for the graupel-like snowflakes of hexagonal type. These definitions are important to determine single scattering properties for snow hydrometeors used as input (along with cloud particle properties and atmospheric parameters) into the Passive and Active Microwave radiative TRAnsfer model (PAMTRA). PAMTRA allows direct comparison of the radar-measured and climate model-based vertical profiles of the radar reflectivity and Doppler velocity for particular precipitation events. The comparison is based on the measurements from the vertically profiling 24-GHz MRR radar operating as part of the cloud-precipitation-meteorological observatory at Princess Elisabeth (PE) base in DML escarpment zone, from 2010 through now. Preliminary results show that MAR simulates well the timing of major synoptic-scale precipitation events, while a bias exists towards higher radar reflectivities using MAR snowfall properties compared to PE MRR measurements. This bias can be related to the differences both in the amount and type of snowflakes reaching the surface. The spatial extent of precipitation also matters as PE provides only vertical profiling. PAMTRA is used to evaluate specific intense snowfall events at PE-centered grid, while MAR-simulated atmospheric fields are further analyzed for understanding the large- and meso-scale atmospheric circulation and moisture transport patterns, together with cloud properties responsible for these events. PE measurements showed that the most intense precipitation events at PE (up to 30 mm water equivalent per day) have been associated with atmospheric rivers, where enhanced tropospheric integrated water vapor amounts are concentrated in narrow long bands stretching from subtropical latitudes to the East Antarctic coast. We analyze representation of such events in MAR, including their extent, intensity, as well as time and location of where such moisture bands are reaching the Antarctic coast.

  7. Control of reactor coolant flow path during reactor decay heat removal

    DOEpatents

    Hunsbedt, Anstein N.

    1988-01-01

    An improved reactor vessel auxiliary cooling system for a sodium cooled nuclear reactor is disclosed. The sodium cooled nuclear reactor is of the type having a reactor vessel liner separating the reactor hot pool on the upstream side of an intermediate heat exchanger and the reactor cold pool on the downstream side of the intermediate heat exchanger. The improvement includes a flow path across the reactor vessel liner flow gap which dissipates core heat across the reactor vessel and containment vessel responsive to a casualty including the loss of normal heat removal paths and associated shutdown of the main coolant liquid sodium pumps. In normal operation, the reactor vessel cold pool is inlet to the suction side of coolant liquid sodium pumps, these pumps being of the electromagnetic variety. The pumps discharge through the core into the reactor hot pool and then through an intermediate heat exchanger where the heat generated in the reactor core is discharged. Upon outlet from the heat exchanger, the sodium is returned to the reactor cold pool. The improvement includes placing a jet pump across the reactor vessel liner flow gap, pumping a small flow of liquid sodium from the lower pressure cold pool into the hot pool. The jet pump has a small high pressure driving stream diverted from the high pressure side of the reactor pumps. During normal operation, the jet pumps supplement the normal reactor pressure differential from the lower pressure cold pool to the hot pool. Upon the occurrence of a casualty involving loss of coolant pump pressure, and immediate cooling circuit is established by the back flow of sodium through the jet pumps from the reactor vessel hot pool to the reactor vessel cold pool. The cooling circuit includes flow into the reactor vessel liner flow gap immediate the reactor vessel wall and containment vessel where optimum and immediate discharge of residual reactor heat occurs.

  8. Neutron fluxes in test reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Youinou, Gilles Jean-Michel

    Communicate the fact that high-power water-cooled test reactors such as the Advanced Test Reactor (ATR), the High Flux Isotope Reactor (HFIR) or the Jules Horowitz Reactor (JHR) cannot provide fast flux levels as high as sodium-cooled fast test reactors. The memo first presents some basics physics considerations about neutron fluxes in test reactors and then uses ATR, HFIR and JHR as an illustration of the performance of modern high-power water-cooled test reactors.

  9. Reactor engineering support of operations at the Davis-Besse nuclear power station

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kelley, D.B.

    1995-12-31

    Reactor engineering functions differ greatly from unit to unit; however, direct support of the reactor operators during reactor startups and operational transients is common to all units. This paper summarizes the support the reactor engineers provide the reactor operators during reactor startups and power changes through the use of automated computer programs at the Davis-Besse nuclear power station.

  10. 10 CFR 2.337 - Evidence at a hearing.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... chapter by the Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, or... the Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, or Director... the Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, or Director...

  11. Nuclear Reactors. Revised.

    ERIC Educational Resources Information Center

    Hogerton, John F.

    This publication is one of a series of information booklets for the general public published by the United States Atomic Energy Commission. Among the topics discussed are: How Reactors Work; Reactor Design; Research, Teaching, and Materials Testing; Reactors (Research, Teaching and Materials); Production Reactors; Reactors for Electric Power…

  12. 10 CFR 2.337 - Evidence at a hearing.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... chapter by the Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, or... the Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, or Director... the Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, or Director...

  13. Nuclear reactor construction with bottom supported reactor vessel

    DOEpatents

    Sharbaugh, John E.

    1987-01-01

    An improved liquid metal nuclear reactor construction has a reactor core and a generally cylindrical reactor vessel for holding a large pool of low pressure liquid metal coolant and housing the core within the pool. The reactor vessel has an open top end, a closed flat bottom end wall and a continuous cylindrical closed side wall interconnecting the top end and bottom end wall. The reactor also has a generally cylindrical concrete containment structure surrounding the reactor vessel and being formed by a cylindrical side wall spaced outwardly from the reactor vessel side wall and a flat base mat spaced below the reactor vessel bottom end wall. A central support pedestal is anchored to the containment structure base mat and extends upwardly therefrom to the reactor vessel and upwardly therefrom to the reactor core so as to support the bottom end wall of the reactor vessel and the lower end of the reactor core in spaced apart relationship above the containment structure base mat. Also, an annular reinforced support structure is disposed in the reactor vessel on the bottom end wall thereof and extends about the lower end of the core so as to support the periphery thereof. In addition, an annular support ring having a plurality of inward radially extending linear members is disposed between the containment structure base mat and the bottom end of the reactor vessel wall and is connected to and supports the reactor vessel at its bottom end on the containment structure base mat so as to allow the reactor vessel to expand radially but substantially prevent any lateral motions that might be imposed by the occurrence of a seismic event. The reactor construction also includes a bed of insulating material in sand-like granular form, preferably being high density magnesium oxide particles, disposed between the containment structure base mat and the bottom end wall of the reactor vessel and uniformly supporting the reactor vessel at its bottom end wall on the containment structure base mat so as to insulate the reactor vessel bottom end wall from the containment structure base mat and allow the reactor vessel bottom end wall to freely expand as it heats up while providing continuous support thereof. Further, a deck is supported upon the side wall of the containment structure above the top open end of the reactor vessel, and a plurality of serially connected extendible and retractable annular bellows extend between the deck and the top open end of the reactor vessel and flexibly and sealably interconnect the reactor vessel at its top end to the deck. An annular guide ring is disposed on the containment structure and extends between its side wall and the top open end of the reactor vessel for providing lateral support of the reactor vessel top open end by limiting imposition of lateral loads on the annular bellows by the occurrence of a lateral seismic event.

  14. Request for Naval Reactors Comment on Proposed Prometheus Space Flight Nuclear Reactor High Tier Reactor Safety Requirements and for Naval Reactors Approval to Transmit These Requirements to JPL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D. Kokkinos

    2005-04-28

    The purpose of this letter is to request Naval Reactors comments on the nuclear reactor high tier requirements for the PROMETHEUS space flight reactor design, pre-launch operations, launch, ascent, operation, and disposal, and to request Naval Reactors approval to transmit these requirements to Jet Propulsion Laboratory to ensure consistency between the reactor safety requirements and the spacecraft safety requirements. The proposed PROMETHEUS nuclear reactor high tier safety requirements are consistent with the long standing safety culture of the Naval Reactors Program and its commitment to protecting the health and safety of the public and the environment. In addition, the philosophymore » on which these requirements are based is consistent with the Nuclear Safety Policy Working Group recommendations on space nuclear propulsion safety (Reference 1), DOE Nuclear Safety Criteria and Specifications for Space Nuclear Reactors (Reference 2), the Nuclear Space Power Safety and Facility Guidelines Study of the Applied Physics Laboratory.« less

  15. Heat transfer analysis of cylindrical anaerobic reactors with different sizes: a heat transfer model.

    PubMed

    Liu, Jiawei; Zhou, Xingqiu; Wu, Jiangdong; Gao, Wen; Qian, Xu

    2017-10-01

    The temperature is the essential factor that influences the efficiency of anaerobic reactors. During the operation of the anaerobic reactor, the fluctuations of ambient temperature can cause a change in the internal temperature of the reactor. Therefore, insulation and heating measures are often used to maintain anaerobic reactor's internal temperature. In this paper, a simplified heat transfer model was developed to study heat transfer between cylindrical anaerobic reactors and their surroundings. Three cylindrical reactors of different sizes were studied, and the internal relations between ambient temperature, thickness of insulation, and temperature fluctuations of the reactors were obtained at different reactor sizes. The model was calibrated by a sensitivity analysis, and the calibrated model was well able to predict reactor temperature. The Nash-Sutcliffe model efficiency coefficient was used to assess the predictive power of heat transfer models. The Nash coefficients of the three reactors were 0.76, 0.60, and 0.45, respectively. The model can provide reference for the thermal insulation design of cylindrical anaerobic reactors.

  16. Solvent refined coal reactor quench system

    DOEpatents

    Thorogood, Robert M.

    1983-01-01

    There is described an improved SRC reactor quench system using a condensed product which is recycled to the reactor and provides cooling by evaporation. In the process, the second and subsequent reactors of a series of reactors are cooled by the addition of a light oil fraction which provides cooling by evaporation in the reactor. The vaporized quench liquid is recondensed from the reactor outlet vapor stream.

  17. Solvent refined coal reactor quench system

    DOEpatents

    Thorogood, R.M.

    1983-11-08

    There is described an improved SRC reactor quench system using a condensed product which is recycled to the reactor and provides cooling by evaporation. In the process, the second and subsequent reactors of a series of reactors are cooled by the addition of a light oil fraction which provides cooling by evaporation in the reactor. The vaporized quench liquid is recondensed from the reactor outlet vapor stream. 1 fig.

  18. Nuclear reactor neutron shielding

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Speaker, Daniel P; Neeley, Gary W; Inman, James B

    A nuclear reactor includes a reactor pressure vessel and a nuclear reactor core comprising fissile material disposed in a lower portion of the reactor pressure vessel. The lower portion of the reactor pressure vessel is disposed in a reactor cavity. An annular neutron stop is located at an elevation above the uppermost elevation of the nuclear reactor core. The annular neutron stop comprises neutron absorbing material filling an annular gap between the reactor pressure vessel and the wall of the reactor cavity. The annular neutron stop may comprise an outer neutron stop ring attached to the wall of the reactormore » cavity, and an inner neutron stop ring attached to the reactor pressure vessel. An excore instrument guide tube penetrates through the annular neutron stop, and a neutron plug comprising neutron absorbing material is disposed in the tube at the penetration through the neutron stop.« less

  19. Reactor pressure vessel head vents and methods of using the same

    DOEpatents

    Gels, John L; Keck, David J; Deaver, Gerald A

    2014-10-28

    Internal head vents are usable in nuclear reactors and include piping inside of the reactor pressure vessel with a vent in the reactor upper head. Piping extends downward from the upper head and passes outside of the reactor to permit the gas to escape or be forcibly vented outside of the reactor without external piping on the upper head. The piping may include upper and lowers section that removably mate where the upper head joins to the reactor pressure vessel. The removable mating may include a compressible bellows and corresponding funnel. The piping is fabricated of nuclear-reactor-safe materials, including carbon steel, stainless steel, and/or a Ni--Cr--Fe alloy. Methods install an internal head vent in a nuclear reactor by securing piping to an internal surface of an upper head of the nuclear reactor and/or securing piping to an internal surface of a reactor pressure vessel.

  20. Proposed Advanced Reactor Adaptation of the Standard Review Plan NUREG-0800 Chapter 4 (Reactor) for Sodium-Cooled Fast Reactors and Modular High-Temperature Gas-Cooled Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Belles, Randy; Poore, III, Willis P.; Brown, Nicholas R.

    2017-03-01

    This report proposes adaptation of the previous regulatory gap analysis in Chapter 4 (Reactor) of NUREG 0800, Standard Review Plan (SRP) for the Review of Safety Analysis Reports for Nuclear Power Plants: LWR [Light Water Reactor] Edition. The proposed adaptation would result in a Chapter 4 review plan applicable to certain advanced reactors. This report addresses two technologies: the sodium-cooled fast reactor (SFR) and the modular high temperature gas-cooled reactor (mHTGR). SRP Chapter 4, which addresses reactor components, was selected for adaptation because of the possible significant differences in advanced non-light water reactor (non-LWR) technologies compared with the current LWR-basedmore » description in Chapter 4. SFR and mHTGR technologies were chosen for this gap analysis because of their diverse designs and the availability of significant historical design detail.« less

  1. 10 CFR 52.167 - Issuance of manufacturing license.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... proposed reactor(s) can be incorporated into a nuclear power plant and operated at sites having... design and manufacture the proposed nuclear power reactor(s); (5) The proposed inspections, tests... the construction of a nuclear power facility using the manufactured reactor(s). (2) A holder of a...

  2. A novel plant protection strategy for transient reactors

    NASA Astrophysics Data System (ADS)

    Bhattacharyya, Samit K.; Lipinski, Walter C.; Hanan, Nelson A.

    A novel plant protection system designed for use in the TREAT Upgrade (TU) reactor is described. The TU reactor is designed for controlled transient operation in the testing of reactor fuel behavior under simulated reactor accident conditions. Safe operation of the reactor is of paramount importance and the Plant Protection System (PPS) had to be designed to exacting requirements. Researchers believe that the strategy developed for the TU has potential application to the multimegawatt space reactors and represents the state of the art in terrestrial transient reactor protection systems.

  3. Process and apparatus for adding and removing particles from pressurized reactors

    DOEpatents

    Milligan, John D.

    1983-01-01

    A method for adding and removing fine particles from a pressurized reactor is provided, which comprises connecting the reactor to a container, sealing the container from the reactor, filling the container with particles and a liquid material compatible with the reactants, pressurizing the container to substantially the reactor pressure, removing the seal between the reactor and the container, permitting particles to fall into or out of the reactor, and resealing the container from the reactor. An apparatus for adding and removing particles is also disclosed.

  4. Effects of imperfect mixing on low-density polyethylene reactor dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Villa, C.M.; Dihora, J.O.; Ray, W.H.

    1998-07-01

    Earlier work considered the effect of feed conditions and controller configuration on the runaway behavior of LDPE autoclave reactors assuming a perfectly mixed reactor. This study provides additional insight on the dynamics of such reactors by using an imperfectly mixed reactor model and bifurcation analysis to show the changes in the stability region when there is imperfect macroscale mixing. The presence of imperfect mixing substantially increases the range of stable operation of the reactor and makes the process much easier to control than for a perfectly mixed reactor. The results of model analysis and simulations are used to identify somemore » of the conditions that lead to unstable reactor behavior and to suggest ways to avoid reactor runaway or reactor extinction during grade transitions and other process operation disturbances.« less

  5. Startup of reactors for anoxic ammonium oxidation: experiences from the first full-scale anammox reactor in Rotterdam.

    PubMed

    van der Star, Wouter R L; Abma, Wiebe R; Blommers, Dennis; Mulder, Jan-Willem; Tokutomi, Takaaki; Strous, Marc; Picioreanu, Cristian; van Loosdrecht, Mark C M

    2007-10-01

    The first full-scale anammox reactor in the world was started in Rotterdam (NL). The reactor was scaled-up directly from laboratory-scale to full-scale and treats up to 750 kg-N/d. In the initial phase of the startup, anammox conversions could not be identified by traditional methods, but quantitative PCR proved to be a reliable indicator for growth of the anammox population, indicating an anammox doubling time of 10-12 days. The experience gained during this first startup in combination with the availability of seed sludge from this reactor, will lead to a faster startup of anammox reactors in the future. The anammox reactor type employed in Rotterdam was compared to other reactor types for the anammox process. Reactors with a high specific surface area like the granular sludge reactor employed in Rotterdam provide the highest volumetric loading rates. Mass transfer of nitrite into the biofilm is limiting the conversion of those reactor types that have a lower specific surface area. Now the first full-scale commercial anammox reactor is in operation, a consistent and descriptive nomenclature is suggested for reactors in which the anammox process is employed.

  6. A small, 1400 K, reactor for Brayton space power systems.

    NASA Technical Reports Server (NTRS)

    Lantz, E.; Mayo, W.

    1972-01-01

    An investigation was conducted to determine minimum dimensions and minimum weight obtainable in a design for a reactor using uranium-233 nitride or plutonium-239 nitride as fuel. Such a reactor had been considered by Krasner et al. (1971). Present space power status is discussed, together with questions of reactor design and power distribution in the reactor. The characteristics of various reactor types are compared, giving attention also to a zirconium hydride reactor.

  7. Alternative approaches to fusion. [reactor design and reactor physics for Tokamak fusion reactors

    NASA Technical Reports Server (NTRS)

    Roth, R. J.

    1976-01-01

    The limitations of the Tokamak fusion reactor concept are discussed and various other fusion reactor concepts are considered that employ the containment of thermonuclear plasmas by magnetic fields (i.e., stellarators). Progress made in the containment of plasmas in toroidal devices is reported. Reactor design concepts are illustrated. The possibility of using fusion reactors as a power source in interplanetary space travel and electric power plants is briefly examined.

  8. 10 CFR 50.46a - Acceptance criteria for reactor coolant system venting systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Acceptance criteria for reactor coolant system venting... criteria for reactor coolant system venting systems. Each nuclear power reactor must be provided with high point vents for the reactor coolant system, for the reactor vessel head, and for other systems required...

  9. 10 CFR 50.46a - Acceptance criteria for reactor coolant system venting systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Acceptance criteria for reactor coolant system venting... criteria for reactor coolant system venting systems. Each nuclear power reactor must be provided with high point vents for the reactor coolant system, for the reactor vessel head, and for other systems required...

  10. KINETICS OF TREAT USED AS A TEST REACTOR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dickerman, C.E.; Johnson, R.D.; Gasidlo, J.

    1962-05-01

    An analysis is presented concerning the reactor kinetics of TREAT used as a pulsed, engineering test reactor for fast reactor fuel element studies. A description of the reactor performance is given for a wide range of conditions associated with its use as a test reactor. Supplemental information on meltdown experimentation is included. (J.R.D.)

  11. Generating unstructured nuclear reactor core meshes in parallel

    DOE PAGES

    Jain, Rajeev; Tautges, Timothy J.

    2014-10-24

    Recent advances in supercomputers and parallel solver techniques have enabled users to run large simulations problems using millions of processors. Techniques for multiphysics nuclear reactor core simulations are under active development in several countries. Most of these techniques require large unstructured meshes that can be hard to generate in a standalone desktop computers because of high memory requirements, limited processing power, and other complexities. We have previously reported on a hierarchical lattice-based approach for generating reactor core meshes. Here, we describe efforts to exploit coarse-grained parallelism during reactor assembly and reactor core mesh generation processes. We highlight several reactor coremore » examples including a very high temperature reactor, a full-core model of the Korean MONJU reactor, a ¼ pressurized water reactor core, the fast reactor Experimental Breeder Reactor-II core with a XX09 assembly, and an advanced breeder test reactor core. The times required to generate large mesh models, along with speedups obtained from running these problems in parallel, are reported. A graphical user interface to the tools described here has also been developed.« less

  12. Nuclear reactor having a polyhedral primary shield and removable vessel insulation

    DOEpatents

    Ekeroth, Douglas E.; Orr, Richard

    1993-01-01

    A nuclear reactor is provided having a generally cylindrical reactor vessel disposed within an opening in a primary shield. The opening in the primary shield is defined by a plurality of generally planar side walls forming a generally polyhedral-shaped opening. The reactor vessel is supported within the opening in the primary shield by reactor vessel supports which are in communication and aligned with central portions of some of the side walls. The reactor vessel is connected to the central portions of the reactor vessel supports. A thermal insulation polyhedron formed from a plurality of slidably insertable and removable generally planar insulation panels substantially surrounds at least a portion of the reactor vessel and is disposed between the reactor vessel and the side walls of the primary shield. The shape of the insulation polyhedron generally corresponds to the shape of the opening in the primary shield. Reactor monitoring instrumentation may be mounted in the corners of the opening in the primary shield between the side walls and the reactor vessel such that insulation is not disposed between the instrumentation and the reactor vessel.

  13. Nuclear reactor having a polyhedral primary shield and removable vessel insulation

    DOEpatents

    Ekeroth, D.E.; Orr, R.

    1993-12-07

    A nuclear reactor is provided having a generally cylindrical reactor vessel disposed within an opening in a primary shield. The opening in the primary shield is defined by a plurality of generally planar side walls forming a generally polyhedral-shaped opening. The reactor vessel is supported within the opening in the primary shield by reactor vessel supports which are in communication and aligned with central portions of some of the side walls. The reactor vessel is connected to the central portions of the reactor vessel supports. A thermal insulation polyhedron formed from a plurality of slidably insertable and removable generally planar insulation panels substantially surrounds at least a portion of the reactor vessel and is disposed between the reactor vessel and the side walls of the primary shield. The shape of the insulation polyhedron generally corresponds to the shape of the opening in the primary shield. Reactor monitoring instrumentation may be mounted in the corners of the opening in the primary shield between the side walls and the reactor vessel such that insulation is not disposed between the instrumentation and the reactor vessel. 5 figures.

  14. Boiling water neutronic reactor incorporating a process inherent safety design

    DOEpatents

    Forsberg, C.W.

    1985-02-19

    A boiling-water reactor core is positioned within a prestressed concrete reactor vessel of a size which will hold a supply of coolant water sufficient to submerge and cool the reactor core by boiling for a period of at least one week after shutdown. Separate volumes of hot, clean (nonborated) water for cooling during normal operation and cool highly borated water for emergency cooling and reactor shutdown are separated by an insulated wall during normal reactor operation with contact between the two water volumes being maintained at interfaces near the top and bottom ends of the reactor vessel. Means are provided for balancing the pressure of the two water volumes at the lower interface zone during normal operation to prevent entry of the cool borated water into the reactor core region, for detecting the onset of excessive power to coolant flow conditions in the reactor core and for detecting low water levels of reactor coolant. Cool borated water is permitted to flow into the reactor core when low reactor coolant levels or excessive power to coolant flow conditions are encountered.

  15. Boiling water neutronic reactor incorporating a process inherent safety design

    DOEpatents

    Forsberg, Charles W.

    1987-01-01

    A boiling-water reactor core is positioned within a prestressed concrete reactor vessel of a size which will hold a supply of coolant water sufficient to submerge and cool the reactor core by boiling for a period of at least one week after shutdown. Separate volumes of hot, clean (non-borated) water for cooling during normal operation and cool highly borated water for emergency cooling and reactor shutdown are separated by an insulated wall during normal reactor operation with contact between the two water volumes being maintained at interfaces near the top and bottom ends of the reactor vessel. Means are provided for balancing the pressure of the two volumes at the lower interface zone during normal operation to prevent entry of the cool borated water into the reactor core region, for detecting the onset of excessive power to coolant flow conditions in the reactor core and for detecting low water levels of reactor coolant. Cool borated water is permitted to flow into the reactor core when low reactor coolant levels or excessive power to coolant flow conditions are encountered.

  16. Summary of NR Program Prometheus Efforts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J Ashcroft; C Eshelman

    2006-02-08

    The Naval Reactors Program led work on the development of a reactor plant system for the Prometheus space reactor program. The work centered on a 200 kWe electric reactor plant with a 15-20 year mission applicable to nuclear electric propulsion (NEP). After a review of all reactor and energy conversion alternatives, a direct gas Brayton reactor plant was selected for further development. The work performed subsequent to this selection included preliminary nuclear reactor and reactor plant design, development of instrumentation and control techniques, modeling reactor plant operational features, development and testing of core and plant material options, and development ofmore » an overall project plan. Prior to restructuring of the program, substantial progress had been made on defining reference plant operating conditions, defining reactor mechanical, thermal and nuclear performance, understanding the capabilities and uncertainties provided by material alternatives, and planning non-nuclear and nuclear system testing. The mission requirements for the envisioned NEP missions cannot be accommodated with existing reactor technologies. Therefore concurrent design, development and testing would be needed to deliver a functional reactor system. Fuel and material performance beyond the current state of the art is needed. There is very little national infrastructure available for fast reactor nuclear testing and associated materials development and testing. Surface mission requirements may be different enough to warrant different reactor design approaches and development of a generic multi-purpose reactor requires substantial sacrifice in performance capability for each mission.« less

  17. METHOD AND APPARATUS FOR CONTROLLING DIRECT-CYCLE NEUTRONIC REACTORS

    DOEpatents

    Reed, G.A.

    1961-01-10

    A control arrangement is offered for a boiling-water reactor. Boric acid is maintained in the water in the reactor and the amount in the reactor is controlled by continuously removing a portion of the water from the reactor, concentrating the boric acid by evaporating the water therefrom, returning a controlled amount of the acid to the reactor, and simultaneously controlling the water level by varying the rate of spent steam return to the reactor.

  18. Control Means for Reactor

    DOEpatents

    Manley, J. H.

    1961-06-27

    An apparatus for controlling a nuclear reactor includes a tank just below the reactor, tubes extending from the tank into the reactor, and a thermally expansible liquid neutron absorbent material in the tank. The liquid in the tank is exposed to a beam of neutrons from the reactor which heats the liquid causing it to expand into the reactor when the neutron flux in the reactor rises above a predetermincd danger point. Boron triamine may be used for this purpose.

  19. 10 CFR 2.621 - Acceptance and docketing of application for early review of site suitability issues in a combined...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will inform the... Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will accept for... New Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, that they...

  20. 10 CFR 2.621 - Acceptance and docketing of application for early review of site suitability issues in a combined...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will inform the... Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will accept for... New Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, that they...

  1. Low temperature pre-treatment of domestic sewage in an anaerobic hybrid or an anaerobic filter reactor.

    PubMed

    Elmitwalli, Tarek A; Sklyar, Vladimir; Zeeman, Grietje; Lettinga, Gatze

    2002-05-01

    The pre-treatment of domestic sewage for removal of suspended solids (SS) at a process temperature of 13 degrees C and an hydraulic retention time (HRT) of 4 h was investigated in an anaerobic filter (AF) and anaerobic hybrid (AH) reactor. The AF and the top of the AH reactor consisted of vertical sheets of reticulated polyurethane foam (RPF) with knobs. All biomass in the AF was only in attached form to avoid clogging and sludge washout. The AF reactor showed a significantly higher removal of total and suspended chemical oxygen demand (COD) than the AH reactor, respectively, 55% and 82% in the AF reactor and 34% and 53% in the AH reactor. Because the reactors were operated at a short HRT and low temperature, the hydrolysis, acidification and methanogenesis based on the influent COD were limited to, respectively, 12%, 21% and 23% for the AF reactor and 12%, 17% and 16% for the AH reactor. The excess sludge from the AH reactor was more stabilised and had a better settling capacity and dewaterability. However, the excess sludge from both the AH and AF reactors needed stabilisation. Therefore, the AF reactor is recommended for the pretreatment of domestic sewage at low temperatures.

  2. Nuclear reactor cavity floor passive heat removal system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Edwards, Tyler A.; Neeley, Gary W.; Inman, James B.

    A nuclear reactor includes a reactor core disposed in a reactor pressure vessel. A radiological containment contains the nuclear reactor and includes a concrete floor located underneath the nuclear reactor. An ex vessel corium retention system includes flow channels embedded in the concrete floor located underneath the nuclear reactor, an inlet in fluid communication with first ends of the flow channels, and an outlet in fluid communication with second ends of the flow channels. In some embodiments the inlet is in fluid communication with the interior of the radiological containment at a first elevation and the outlet is in fluidmore » communication with the interior of the radiological containment at a second elevation higher than the first elevation. The radiological containment may include a reactor cavity containing a lower portion of the pressure vessel, wherein the concrete floor located underneath the nuclear reactor is the reactor cavity floor.« less

  3. Methods and apparatuses for deoxygenating pyrolysis oil

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baird, Lance Awender; Brandvold, Timothy A.; Frey, Stanley Joseph

    Methods and apparatuses are provided for deoxygenating pyrolysis oil. A method includes contacting a pyrolysis oil with a deoxygenation catalyst in a first reactor at deoxygenation conditions to produce a first reactor effluent. The first reactor effluent has a first oxygen concentration and a first hydrogen concentration, based on hydrocarbons in the first reactor effluent, and the first reactor effluent includes an aromatic compound. The first reactor effluent is contacted with a dehydrogenation catalyst in a second reactor at conditions that deoxygenate the first reactor effluent while preserving the aromatic compound to produce a second reactor effluent. The second reactormore » effluent has a second oxygen concentration lower than the first oxygen concentration and a second hydrogen concentration that is equal to or lower than the first hydrogen concentration, where the second oxygen concentration and the second hydrogen concentration are based on the hydrocarbons in the second reactor effluent.« less

  4. Methanation assembly using multiple reactors

    DOEpatents

    Jahnke, Fred C.; Parab, Sanjay C.

    2007-07-24

    A methanation assembly for use with a water supply and a gas supply containing gas to be methanated in which a reactor assembly has a plurality of methanation reactors each for methanating gas input to the assembly and a gas delivery and cooling assembly adapted to deliver gas from the gas supply to each of said methanation reactors and to combine water from the water supply with the output of each methanation reactor being conveyed to a next methanation reactor and carry the mixture to such next methanation reactor.

  5. When Do Commercial Reactors Permanently Shut Down?

    EIA Publications

    2011-01-01

    For those wishing to obtain current data, the following resources are available: U.S. reactors, go to the Energy Information Administration's nuclear reactor shutdown list. (Note: As of April 30, 2010, the last U.S. reactor to permanently shut down was Big Rock Point in 1997.) Foreign Reactors, go to the Power Reactor Information System (PRIS) on the International Atomic Energy Agency's website.

  6. 10 CFR 140.11 - Amounts of financial protection for certain reactors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...,000,000 for each nuclear reactor he is authorized to operate at a thermal power level not exceeding ten kilowatts; (2) In the amount of $1,500,000 for each nuclear reactor he is authorized to operate at... amount of $2,500,000 for each nuclear reactor other than a testing reactor or a reactor licensed under...

  7. 10 CFR 2.603 - Acceptance and docketing of application for early review of site suitability issues in a...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will... Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will... Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, that they are...

  8. 10 CFR 140.11 - Amounts of financial protection for certain reactors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...,000,000 for each nuclear reactor he is authorized to operate at a thermal power level not exceeding ten kilowatts; (2) In the amount of $1,500,000 for each nuclear reactor he is authorized to operate at... amount of $2,500,000 for each nuclear reactor other than a testing reactor or a reactor licensed under...

  9. 10 CFR 2.603 - Acceptance and docketing of application for early review of site suitability issues in a...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will... Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, will... Reactors or the Director of the Office of Nuclear Reactor Regulation, as appropriate, that they are...

  10. 10 CFR 140.11 - Amounts of financial protection for certain reactors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...,000,000 for each nuclear reactor he is authorized to operate at a thermal power level not exceeding ten kilowatts; (2) In the amount of $1,500,000 for each nuclear reactor he is authorized to operate at... amount of $2,500,000 for each nuclear reactor other than a testing reactor or a reactor licensed under...

  11. Determination of the Sensitivity of the Antineutrino Probe for Reactor Core Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cormon, S.; Fallot, M., E-mail: fallot@subatech.in2p3.fr; Bui, V.-M.

    This paper presents a feasibility study of the use of the detection of reactor-antineutrinos (ν{sup ¯}{sub e}) for non proliferation purpose. To proceed, we have started to study different reactor designs with our simulation tools. We use a package called MCNP Utility for Reactor Evolution (MURE), initially developed by CNRS/IN2P3 labs to study Generation IV reactors. The MURE package has been coupled to fission product beta decay nuclear databases for studying reactor antineutrino emission. This method is the only one able to predict the antineutrino emission from future reactor cores, which don't use the thermal fission of {sup 235}U, {supmore » 239}Pu and {sup 241}Pu. It is also the only way to include off-equilibrium effects, due to neutron captures and time evolution of the fission product concentrations during a reactor cycle. We will present here the first predictions of antineutrino energy spectra from innovative reactor designs (Generation IV reactors). We will then discuss a summary of our results of non-proliferation scenarios involving the latter reactor designs, taking into account reactor physics constraints.« less

  12. Bioaugmentation of activated sludge towards 3-chloroaniline removal with a mixed bacterial population carrying a degradative plasmid.

    PubMed

    Bathe, Stephan; Schwarzenbeck, Norbert; Hausner, Martina

    2009-06-01

    A bioaugmentation approach combining several strategies was applied to achieve degradation of 3-chloroaniline (3CA) in semicontinuous activated sludge reactors. In a first step, a 3CA-degrading Comamonas testosteroni strain carrying the degradative plasmid pNB2 was added to a biofilm reactor, and complete 3CA degradation together with spread of the plasmid within the indigenous biofilm population was achieved. A second set of reactors was then bioaugmented with either a suspension of biofilm cells removed from the carrier material or with biofilm-containing carrier material. 3CA degradation was established rapidly in all bioaugmented reactors, followed by a slow adaptation of the non-bioaugmented control reactors. In response to variations in 3CA concentration, all reactors exhibited temporary performance breakdowns. Whereas duplicates of the control reactors deviated in their behaviour, the bioaugmented reactors appeared more reproducible in their performance and population dynamics. Finally, the carrier-bioaugmented reactors showed an improved performance in the presence of high 3CA influent concentrations over the suspension-bioaugmented reactors. In contrast, degradation in one control reactor failed completely, but was rapidly established in the remaining control reactor.

  13. A comparative study of thermophilic and mesophilic anaerobic co-digestion of food waste and wheat straw: Process stability and microbial community structure shifts.

    PubMed

    Shi, Xuchuan; Guo, Xianglin; Zuo, Jiane; Wang, Yajiao; Zhang, Mengyu

    2018-05-01

    Renewable energy recovery from organic solid waste via anaerobic digestion is a promising way to provide sustainable energy supply and eliminate environmental pollution. However, poor efficiency and operational problems hinder its wide application of anaerobic digestion. The effects of two key parameters, i.e. temperature and substrate characteristics on process stability and microbial community structure were studied using two lab-scale anaerobic reactors under thermophilic and mesophilic conditions. Both the reactors were fed with food waste (FW) and wheat straw (WS). The organic loading rates (OLRs) were maintained at a constant level of 3 kg VS/(m 3 ·d). Five different FW:WS substrate ratios were utilized in different operational phases. The synergetic effects of co-digestion improved the stability and performance of the reactors. When FW was mono-digested, both reactors were unstable. The mesophilic reactor eventually failed due to volatile fatty acid accumulation. The thermophilic reactor had better performance compared to mesophilic one. The biogas production rate of the thermophilic reactor was 4.9-14.8% higher than that of mesophilic reactor throughout the experiment. The shifts in microbial community structures throughout the experiment in both thermophilic and mesophilic reactors were investigated. With increasing FW proportions, bacteria belonging to the phylum Thermotogae became predominant in the thermophilic reactor, while the phylum Bacteroidetes was predominant in the mesophilic reactor. The genus Methanosarcina was the predominant methanogen in the thermophilic reactor, while the genus Methanothrix remained predominant in the mesophilic reactor. The methanogenesis pathway shifted from acetoclastic to hydrogenotrophic when the mesophilic reactor experienced perturbations. Moreover, the population of lignocellulose-degrading microorganisms in the thermophilic reactor was higher than those in mesophilic reactor, which explained the better performance of the thermophilic reactor. Copyright © 2018. Published by Elsevier Ltd.

  14. Coupled reactor kinetics and heat transfer model for heat pipe cooled reactors

    NASA Astrophysics Data System (ADS)

    Wright, Steven A.; Houts, Michael

    2001-02-01

    Heat pipes are often proposed as cooling system components for small fission reactors. SAFE-300 and STAR-C are two reactor concepts that use heat pipes as an integral part of the cooling system. Heat pipes have been used in reactors to cool components within radiation tests (Deverall, 1973); however, no reactor has been built or tested that uses heat pipes solely as the primary cooling system. Heat pipe cooled reactors will likely require the development of a test reactor to determine the main differences in operational behavior from forced cooled reactors. The purpose of this paper is to describe the results of a systems code capable of modeling the coupling between the reactor kinetics and heat pipe controlled heat transport. Heat transport in heat pipe reactors is complex and highly system dependent. Nevertheless, in general terms it relies on heat flowing from the fuel pins through the heat pipe, to the heat exchanger, and then ultimately into the power conversion system and heat sink. A system model is described that is capable of modeling coupled reactor kinetics phenomena, heat transfer dynamics within the fuel pins, and the transient behavior of heat pipes (including the melting of the working fluid). This paper focuses primarily on the coupling effects caused by reactor feedback and compares the observations with forced cooled reactors. A number of reactor startup transients have been modeled, and issues such as power peaking, and power-to-flow mismatches, and loading transients were examined, including the possibility of heat flow from the heat exchanger back into the reactor. This system model is envisioned as a tool to be used for screening various heat pipe cooled reactor concepts, for designing and developing test facility requirements, for use in safety evaluations, and for developing test criteria for in-pile and out-of-pile test facilities. .

  15. Technical Application of Nuclear Fission

    NASA Astrophysics Data System (ADS)

    Denschlag, J. O.

    The chapter is devoted to the practical application of the fission process, mainly in nuclear reactors. After a historical discussion covering the natural reactors at Oklo and the first attempts to build artificial reactors, the fundamental principles of chain reactions are discussed. In this context chain reactions with fast and thermal neutrons are covered as well as the process of neutron moderation. Criticality concepts (fission factor η, criticality factor k) are discussed as well as reactor kinetics and the role of delayed neutrons. Examples of specific nuclear reactor types are presented briefly: research reactors (TRIGA and ILL High Flux Reactor), and some reactor types used to drive nuclear power stations (pressurized water reactor [PWR], boiling water reactor [BWR], Reaktor Bolshoi Moshchnosti Kanalny [RBMK], fast breeder reactor [FBR]). The new concept of the accelerator-driven systems (ADS) is presented. The principle of fission weapons is outlined. Finally, the nuclear fuel cycle is briefly covered from mining, chemical isolation of the fuel and preparation of the fuel elements to reprocessing the spent fuel and conditioning for deposit in a final repository.

  16. Effects of catalyst concentration and ultraviolet intensity on chemical mechanical polishing of GaN

    NASA Astrophysics Data System (ADS)

    Wang, Jie; Wang, Tongqing; Pan, Guoshun; Lu, Xinchun

    2016-08-01

    Effects of catalyst concentration and ultraviolet intensity on chemical mechanical polishing (CMP) of GaN were deeply investigated in this paper. Working as an ideal homogeneous substrate material in LED industry, GaN ought to be equipped with a smooth and flat surface. Taking the strong chemical stability of GaN into account, photocatalytic oxidation technology was adopted in GaN CMP process to realize efficient removal. It was found that, because of the improved reaction rate of photocatalytic oxidation, GaN material removal rate (MRR) increases by a certain extent with catalyst concentration increasing. Cross single line analysis on the surface after polishing by Phase Shift MicroXAM-3D was carried out to prove the better removal effect with higher catalyst concentration. Ultraviolet intensity field in H2O2-SiO2-based polishing system was established and simulated, revealing the variation trend of ultraviolet intensity around the outlet of the slurry. It could be concluded that, owing to the higher planarization efficiency and lower energy damage, the UV lamp of 125 W is the most appropriate lamp in this system. Based on the analysis, defects removal model of this work was proposed to describe the effects of higher catalyst concentration and higher power of UV lamp.

  17. The C3PO project: a laser communication system concept for small satellites

    NASA Astrophysics Data System (ADS)

    d'Humières, Benoît; Esmiller, Bruno; Gouy, Yann; Steck, Emilie; Quintana, Crisanto; Faulkner, Graham; O'Brien, Dominic; Sproll, Fabian; Wagner, Paul; Hampf, Daniel; Riede, Wolfgang; Salter, Michael; Wang, Qin; Platt, Duncan; Jakonis, Darius; Piao, Xiaoyu; Karlsson, Mikael; Oberg, Olof; Petermann, Ingemar; Michalkiewicz, Aneta; Krezel, Jerzy; Debowska, Anna; Thueux, Yoann

    2017-02-01

    The satellite market is shifting towards smaller (micro and nanosatellites), lowered mass and increased performance platforms. Nanosatellites and picosatellites have been used for a number of new, innovative and unique payloads and missions. This trend requires new concepts for a reduced size, a better performance/weight ratio and a reduction of onboard power consumption. In this context, disruptive technologies, such as laser-optical communication systems, are opening new possibilities. This paper presents the C3PO1 system, "advanced Concept for laser uplink/ downlink CommuniCation with sPace Objects", and the first results of the development of its key technologies. This project targets the design of a communications system that uses a ground-based laser to illuminate a satellite, and a Modulating Retro-Reflector (MRR) to return a beam of light modulated by data to the ground. This enables a downlink, without a laser source on the satellite. This architecture suits well to small satellite applications so as high data rates are potentially provided with very low board mass. C3PO project aims to achieve data rates of 1Gbit/s between LEO satellites and Earth with a communication payload mass of less than 1kilogram. In this paper, results of the initial experiments and demonstration of the key technologies will be shown.

  18. A cytoplasmic protein, bystin, interacts with trophinin, tastin, and cytokeratin and may be involved in trophinin-mediated cell adhesion between trophoblast and endometrial epithelial cells

    PubMed Central

    Suzuki, Nao; Zara, Jane; Sato, Takaaki; Ong, Edgar; Bakhiet, Nouna; Oshima, Robert G.; Watson, Kellie L.; Fukuda, Michiko N.

    1998-01-01

    Trophinin and tastin form a cell adhesion molecule complex that potentially mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of implantation. Trophinin and tastin, however, do not directly bind to each other, suggesting the presence of an intermediary protein. The present study identifies a cytoplasmic protein, named bystin, that directly binds trophinin and tastin. Bystin consists of 306 amino acid residues and is predicted to contain tyrosine, serine, and threonine residues in contexts conforming to motifs for phosphorylation by protein kinases. Database searches revealed a 53% identity of the predicted peptide sequence with the Drosophila bys (mrr) gene. Direct protein–protein interactions of trophinin, tastin, and bystin analyzed by yeast two-hybrid assays and by in vitro protein binding assays indicated that binding between bystin and trophinin and between bystin and tastin is enhanced when cytokeratin 8 and 18 are present as the third molecule. Immunocytochemistry of bystin showed that bystin colocalizes with trophinin, tastin, and cytokeratins in a human trophoblastic teratocarcinoma cell, HT-H. It is therefore possible that these molecules form a complex and thus are involved in the process of embryo implantation. PMID:9560222

  19. Optimization of multi response in end milling process of ASSAB XW-42 tool steel with liquid nitrogen cooling using Taguchi-grey relational analysis

    NASA Astrophysics Data System (ADS)

    Norcahyo, Rachmadi; Soepangkat, Bobby O. P.

    2017-06-01

    A research was conducted for the optimization of the end milling process of ASSAB XW-42 tool steel with multiple performance characteristics based on the orthogonal array with Taguchi-grey relational analysis method. Liquid nitrogen was applied as a coolant. The experimental studies were conducted under varying the liquid nitrogen cooling flow rates (FL), and the end milling process variables, i.e., cutting speed (Vc), feeding speed (Vf), and axial depth of cut (Aa). The optimized multiple performance characteristics were surface roughness (SR), flank wear (VB), and material removal rate (MRR). An orthogonal array, signal-to-noise (S/N) ratio, grey relational analysis, grey relational grade, and analysis of variance were employed to study the multiple performance characteristics. Experimental results showed that flow rate gave the highest contribution for reducing the total variation of the multiple responses, followed by cutting speed, feeding speed, and axial depth of cut. The minimum surface roughness, flank wear, and maximum material removal rate could be obtained by using the values of flow rate, cutting speed, feeding speed, and axial depth of cut of 0.5 l/minute, 109.9 m/minute, 440 mm/minute, and 0.9 mm, respectively.

  20. Optimally moderated nuclear fission reactor and fuel source therefor

    DOEpatents

    Ougouag, Abderrafi M [Idaho Falls, ID; Terry, William K [Shelley, ID; Gougar, Hans D [Idaho Falls, ID

    2008-07-22

    An improved nuclear fission reactor of the continuous fueling type involves determining an asymptotic equilibrium state for the nuclear fission reactor and providing the reactor with a moderator-to-fuel ratio that is optimally moderated for the asymptotic equilibrium state of the nuclear fission reactor; the fuel-to-moderator ratio allowing the nuclear fission reactor to be substantially continuously operated in an optimally moderated state.

  1. Flow rate analysis of wastewater inside reactor tanks on tofu wastewater treatment plant

    NASA Astrophysics Data System (ADS)

    Mamat; Sintawardani, N.; Astuti, J. T.; Nilawati, D.; Wulan, D. R.; Muchlis; Sriwuryandari, L.; Sembiring, T.; Jern, N. W.

    2017-03-01

    The research aimed to analyse the flow rate of the wastewater inside reactor tanks which were placed a number of bamboo cutting. The resistance of wastewater flow inside reactor tanks might not be occurred and produce biogas fuel optimally. Wastewater from eleven tofu factories was treated by multi-stages anaerobic process to reduce its organic pollutant and produce biogas. Biogas plant has six reactor tanks of which its capacity for waste water and gas dome was 18 m3 and 4.5 m3, respectively. Wastewater was pumped from collecting ponds to reactors by either serial or parallel way. Maximum pump capacity, head, and electrical motor power was 5m3/h, 50m, and 0.75HP, consecutively. Maximum pressure of biogas inside the reactor tanks was 55 mbar higher than atmosphere pressure. A number of 1,400 pieces of cutting bamboo at 50-60 mm diameter and 100 mm length were used as bacteria growth media inside each reactor tank, covering around 14,287 m2 bamboo area, and cross section area of inner reactor was 4,9 m2. In each reactor, a 6 inches PVC pipe was installed vertically as channel. When channels inside reactor were opened, flow rate of wastewater was 6x10-1 L.sec-1. Contrary, when channels were closed on the upper part, wastewater flow inside the first reactor affected and increased gas dome. Initially, wastewater flowed into each reactor by a gravity mode with head difference between the second and third reactor was 15x10-2m. However, head loss at the second reactor was equal to the third reactor by 8,422 x 10-4m. As result, wastewater flow at the second and third reactors were stagnant. To overcome the problem pump in each reactor should be installed in serial mode. In order to reach the output from the first reactor and the others would be equal, and biogas space was not filled by wastewater, therefore biogas production will be optimum.

  2. Operators in the Plum Brook Reactor Facility Control Room

    NASA Image and Video Library

    1970-03-21

    Donald Rhodes, left, and Clyde Greer, right, monitor the operation of the National Aeronautics and Space Administration’s (NASA) Plum Brook Reactor Facility from the control room. The 60-megawatt test reactor, NASA’s only reactor, was the eighth largest test reactor in the world. The facility was built by the Lewis Research Center in the late 1950s to study the effects of radiation on different materials that could be used to construct nuclear propulsion systems for aircraft or rockets. The reactor went critical for the first time in 1961. For the next two years, two operators were on duty 24 hours per day working on the fission process until the reactor reached its full-power level in 1963. Reactor Operators were responsible for monitoring and controlling the reactor systems. Once the reactor was running under normal operating conditions, the work was relatively uneventful. Normally the reactor was kept at a designated power level within certain limits. Occasionally the operators had to increase the power for a certain test. The shift supervisor and several different people would get together and discuss the change before boosting the power. All operators were required to maintain a Reactor Operator License from the Atomic Energy Commission. The license included six months of training, an eight-hour written exam, a four-hour walkaround, and testing on the reactor controls.

  3. 10 CFR 50.70 - Inspections.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Director, Office of Nuclear Reactor Regulation or Director, Office of New Reactors, as appropriate, provide... New Reactors, or the Director, Office of Nuclear Reactor Regulation. All furniture, supplies and... construction permit holder (nuclear power reactor only) shall ensure that the arrival and presence of an NRC...

  4. 10 CFR 50.70 - Inspections.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Director, Office of Nuclear Reactor Regulation or Director, Office of New Reactors, as appropriate, provide... New Reactors, or the Director, Office of Nuclear Reactor Regulation. All furniture, supplies and... construction permit holder (nuclear power reactor only) shall ensure that the arrival and presence of an NRC...

  5. 10 CFR 50.70 - Inspections.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Director, Office of Nuclear Reactor Regulation or Director, Office of New Reactors, as appropriate, provide... New Reactors, or the Director, Office of Nuclear Reactor Regulation. All furniture, supplies and... construction permit holder (nuclear power reactor only) shall ensure that the arrival and presence of an NRC...

  6. 10 CFR 50.70 - Inspections.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Director, Office of Nuclear Reactor Regulation or Director, Office of New Reactors, as appropriate, provide... New Reactors, or the Director, Office of Nuclear Reactor Regulation. All furniture, supplies and... construction permit holder (nuclear power reactor only) shall ensure that the arrival and presence of an NRC...

  7. 10 CFR 50.70 - Inspections.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Director, Office of Nuclear Reactor Regulation or Director, Office of New Reactors, as appropriate, provide... New Reactors, or the Director, Office of Nuclear Reactor Regulation. All furniture, supplies and... construction permit holder (nuclear power reactor only) shall ensure that the arrival and presence of an NRC...

  8. 10 CFR 2.101 - Filing of application.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Reactors, the Director, Office of Nuclear Reactor Regulation, the Director, Office of Nuclear Material... Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of Federal and State... be requested to: (i) Submit to the Director, Office of Nuclear Reactor Regulation, Director, Office...

  9. 10 CFR 2.101 - Filing of application.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Reactors, the Director, Office of Nuclear Reactor Regulation, the Director, Office of Nuclear Material... Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of Federal and State... be requested to: (i) Submit to the Director, Office of Nuclear Reactor Regulation, Director, Office...

  10. Weld monitor and failure detector for nuclear reactor system

    DOEpatents

    Sutton, Jr., Harry G.

    1987-01-01

    Critical but inaccessible welds in a nuclear reactor system are monitored throughout the life of the reactor by providing small aperture means projecting completely through the reactor vessel wall and also through the weld or welds to be monitored. The aperture means is normally sealed from the atmosphere within the reactor. Any incipient failure or cracking of the weld will cause the environment contained within the reactor to pass into the aperture means and thence to the outer surface of the reactor vessel where its presence is readily detected.

  11. Demonstration of Robustness and Integrated Operation of a Series-Bosch System

    NASA Technical Reports Server (NTRS)

    Abney, Morgan B.; Mansell, Matthew J.; Stanley, Christine; Barnett, Bill; Junaedi, Christian; Vilekar, Saurabh A.; Ryan, Kent

    2016-01-01

    Manned missions beyond low Earth orbit will require highly robust, reliable, and maintainable life support systems that maximize recycling of water and oxygen. Bosch technology is one option to maximize oxygen recovery, in the form of water, from metabolically-produced carbon dioxide (CO2). A two stage approach to Bosch, called Series-Bosch, reduces metabolic CO2 with hydrogen (H2) to produce water and solid carbon using two reactors: a Reverse Water-Gas Shift (RWGS) reactor and a carbon formation (CF) reactor. Previous development efforts demonstrated the stand-alone performance of a NASA-designed RWGS reactor designed for robustness against carbon formation, two membrane separators intended to maximize single pass conversion of reactants, and a batch CF reactor with both transit and surface catalysts. In the past year, Precision Combustion, Inc. (PCI) developed and delivered a RWGS reactor for testing at NASA. The reactor design was based on their patented Microlith® technology and was first evaluated under a Phase I Small Business Innovative Research (SBIR) effort in 2010. The RWGS reactor was recently evaluated at NASA to compare its performance and operating conditions with NASA's RWGS reactor. The test results will be provided in this paper. Separately, in 2015, a semi-continuous CF reactor was designed and fabricated at NASA based on the results from batch CF reactor testing. The batch CF reactor and the semi-continuous CF reactor were individually integrated with an upstream RWGS reactor to demonstrate the system operation and to evaluate performance. Here, we compare the performance and robustness to carbon formation of both RWGS reactors. We report the results of the integrated operation of a Series-Bosch system and we discuss the technology readiness level.

  12. Reactor water cleanup system

    DOEpatents

    Gluntz, Douglas M.; Taft, William E.

    1994-01-01

    A reactor water cleanup system includes a reactor pressure vessel containing a reactor core submerged in reactor water. First and second parallel cleanup trains are provided for extracting portions of the reactor water from the pressure vessel, cleaning the extracted water, and returning the cleaned water to the pressure vessel. Each of the cleanup trains includes a heat exchanger for cooling the reactor water, and a cleaner for cleaning the cooled reactor water. A return line is disposed between the cleaner and the pressure vessel for channeling the cleaned water thereto in a first mode of operation. A portion of the cooled water is bypassed around the cleaner during a second mode of operation and returned through the pressure vessel for shutdown cooling.

  13. The role of nuclear reactors in space exploration and development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lipinski, R.J.

    2000-07-01

    The United States has launched more than 20 radioisotopic thermoelectric generators (RTGs) into space over the past 30 yr but has launched only one nuclear reactor, and that was in 1965. Russia has launched more than 30 reactors. The RTGs use the heat of alpha decay of {sup 238}Pu for power and typically generate <1 kW of electricity. Apollo, Pioneer, Voyager, Viking, Galileo, Ulysses, and Cassini all used RTGs. Space reactors use the fission energy of {sup 235}U; typical designs are for 100 to 1000 kW of electricity. The only US space reactor launch (SNAP-10A) was a demonstration mission. Onemore » reason for the lack of space reactor use by the United States was the lack of space missions that required high power. But, another was the assumed negative publicity that would accompany a reactor launch. The net result is that all space reactor programs after 1970 were terminated before an operating space reactor could be developed, and they are now many years from recovering the ability to build them. Two major near-term needs for space reactors are the human exploration of Mars and advanced missions to and beyond the orbit of Jupiter. To help obtain public acceptance of space reactors, one must correct some of the misconceptions concerning space reactors and convey the following facts to the public and to decision makers: Space reactors are 1000 times smaller in power and size than a commercial power reactor. A space reactor at launch is only as radioactive as a pile of dirt 60 m (200 ft) across. A space reactor contains no plutonium at launch. It does not become significantly radioactive until it is turned on, and it will be engineered so that no launch accident can turn it on, even if that means fueling it after launch. The reactor will not be turned on until it is in a high stable orbit or even on an earth-escape trajectory for some missions. The benefits of space reactors are that they give humanity a stairway to the planets and perhaps the stars. They open a new frontier for their children and their grandchildren. They pave the way for all life on earth to move out into the solar system. At one time, humans built and flew space reactors; it is time to do so again.« less

  14. Degradation of Acid Orange 7 Dye in Two Hybrid Plasma Discharge Reactors

    NASA Astrophysics Data System (ADS)

    Shen, Yongjun; Lei, Lecheng; Zhang, Xingwang; Ding, Jiandong

    2014-11-01

    To get an optimized pulsed electrical plasma discharge reactor and to increase the energy utilization efficiency in the removal of pollutants, two hybrid plasma discharge reactors were designed and optimized. The reactors were compared via the discharge characteristics, energy transfer efficiency, the yields of the active species and the energy utilization in dye wastewater degradation. The results showed that under the same AC input power, the characteristics of the discharge waveform of the point-to-plate reactor were better. Under the same AC input power, the two reactors both had almost the same peak voltage of 22 kV. The peak current of the point-to-plate reactor was 146 A, while that of the wire-to-cylinder reactor was only 48.8 A. The peak powers of the point-to-plate reactor and the wire-to-cylinder reactor were 1.38 MW and 1.01 MW, respectively. The energy per pulse of the point-to-plate reactor was 0.2221 J, which was about 29.4% higher than that of the wire-to-cylinder reactor (0.1716 J). To remove 50% Acid Orange 7 (AO7), the energy utilizations of the point-to-plate reactor and the wire-to-cylinder reactor were 1.02 × 10-9 mol/L and 0.61 × 10-9 mol/L, respectively. In the point-to-plate reactor, the concentration of hydrogen peroxide in pure water was 3.6 mmol/L after 40 min of discharge, which was higher than that of the wire-to-cylinder reactor (2.5 mmol/L). The concentration of liquid phase ozone in the point-to-plate reactor (5.7 × 10-2 mmol/L) was about 26.7% higher than that in the wire-to-cylinder reactor (4.5 × 10-2 mmol/L). The analysis results of the variance showed that the type of reactor and reaction time had significant impacts on the yields of the hydrogen peroxide and ozone. The main degradation intermediates of AO7 identified by gas chromatography and mass spectrometry (GCMS) were acetic acid, maleic anhydride, p-benzoquinone, phenol, benzoic acid, phthalic anhydride, coumarin and 2-naphthol. Proposed degradation pathways were elucidated in light of the analyzed degradation products.

  15. 10 CFR 72.1 - Purpose.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.1 Purpose. The... receive, transfer, and possess power reactor spent fuel, power reactor-related Greater than Class C (GTCC... reactor spent fuel, high-level radioactive waste, power reactor-related GTCC waste, and other radioactive...

  16. 10 CFR 72.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Provisions § 72.1 Purpose. The... receive, transfer, and possess power reactor spent fuel, power reactor-related Greater than Class C (GTCC... reactor spent fuel, high-level radioactive waste, power reactor-related GTCC waste, and other radioactive...

  17. Unmixed fuel processors and methods for using the same

    DOEpatents

    Kulkarni, Parag Prakash; Cui, Zhe

    2010-08-24

    Disclosed herein are unmixed fuel processors and methods for using the same. In one embodiment, an unmixed fuel processor comprises: an oxidation reactor comprising an oxidation portion and a gasifier, a CO.sub.2 acceptor reactor, and a regeneration reactor. The oxidation portion comprises an air inlet, effluent outlet, and an oxygen transfer material. The gasifier comprises a solid hydrocarbon fuel inlet, a solids outlet, and a syngas outlet. The CO.sub.2 acceptor reactor comprises a water inlet, a hydrogen outlet, and a CO.sub.2 sorbent, and is configured to receive syngas from the gasifier. The regeneration reactor comprises a water inlet and a CO.sub.2 stream outlet. The regeneration reactor is configured to receive spent CO.sub.2 adsorption material from the gasification reactor and to return regenerated CO.sub.2 adsorption material to the gasification reactor, and configured to receive oxidized oxygen transfer material from the oxidation reactor and to return reduced oxygen transfer material to the oxidation reactor.

  18. Thermionic switched self-actuating reactor shutdown system

    DOEpatents

    Barrus, Donald M.; Shires, Charles D.; Brummond, William A.

    1989-01-01

    A self-actuating reactor shutdown system incorporating a thermionic switched electromagnetic latch arrangement which is responsive to reactor neutron flux changes and to reactor coolant temperature changes. The system is self-actuating in that the sensing thermionic device acts directly to release (scram) the control rod (absorber) without reference or signal from the main reactor plant protective and control systems. To be responsive to both temperature and neutron flux effects, two detectors are used, one responsive to reactor coolant temperatures, and the other responsive to reactor neutron flux increase. The detectors are incorporated into a thermionic diode connected electrically with an electromagnetic mechanism which under normal reactor operating conditions holds the the control rod in its ready position (exterior of the reactor core). Upon reaching either a specified temperature or neutron flux, the thermionic diode functions to short-circuit the electromagnetic mechanism causing same to lose its holding power and release the control rod, which drops into the reactor core region under gravitational force.

  19. Thermal insulating barrier and neutron shield providing integrated protection for a nuclear reactor vessel

    DOEpatents

    Schreiber, R.B.; Fero, A.H.; Sejvar, J.

    1997-12-16

    The reactor vessel of a nuclear reactor installation which is suspended from the cold leg nozzles in a reactor cavity is provided with a lower thermal insulating barrier spaced from the reactor vessel to form a chamber which can be flooded with cooling water through passive valving to directly cool the reactor vessel in the event of a severe accident. The passive valving also includes bistable vents at the upper end of the thermal insulating barrier for releasing steam. A removable, modular neutron shield extending around the upper end of the reactor cavity below the nozzles forms with the upwardly and outwardly tapered transition on the outer surface of the reactor vessel, a labyrinthine channel which reduces neutron streaming while providing a passage for the escape of steam during a severe accident, and for the cooling air which is circulated along the reactor cavity walls outside the thermal insulating barrier during normal operation of the reactor. 8 figs.

  20. Thermal insulating barrier and neutron shield providing integrated protection for a nuclear reactor vessel

    DOEpatents

    Schreiber, Roger B.; Fero, Arnold H.; Sejvar, James

    1997-01-01

    The reactor vessel of a nuclear reactor installation which is suspended from the cold leg nozzles in a reactor cavity is provided with a lower thermal insulating barrier spaced from the reactor vessel to form a chamber which can be flooded with cooling water through passive valving to directly cool the reactor vessel in the event of a severe accident. The passive valving also includes bistable vents at the upper end of the thermal insulating barrier for releasing steam. A removable, modular neutron shield extending around the upper end of the reactor cavity below the nozzles forms with the upwardly and outwardly tapered transition on the outer surface of the reactor vessel, a labyrinthine channel which reduces neutron streaming while providing a passage for the escape of steam during a severe accident, and for the cooling air which is circulated along the reactor cavity walls outside the thermal insulating barrier during normal operation of the reactor.

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soldevilla, M.; Salmons, S.; Espinosa, B.

    The new application BDDR (Reactor database) has been developed at CEA in order to manage nuclear reactors technological and operating data. This application is a knowledge management tool which meets several internal needs: -) to facilitate scenario studies for any set of reactors, e.g. non-proliferation assessments; -) to make core physics studies easier, whatever the reactor design (PWR-Pressurized Water Reactor-, BWR-Boiling Water Reactor-, MAGNOX- Magnesium Oxide reactor-, CANDU - CANada Deuterium Uranium-, FBR - Fast Breeder Reactor -, etc.); -) to preserve the technological data of all reactors (past and present, power generating or experimental, naval propulsion,...) in a uniquemore » repository. Within the application database are enclosed location data and operating history data as well as a tree-like structure containing numerous technological data. These data address all kinds of reactors features and components. A few neutronics data are also included (neutrons fluxes). The BDDR application is based on open-source technologies and thin client/server architecture. The software architecture has been made flexible enough to allow for any change. (authors)« less

  2. Propellant actuated nuclear reactor steam depressurization valve

    DOEpatents

    Ehrke, Alan C.; Knepp, John B.; Skoda, George I.

    1992-01-01

    A nuclear fission reactor combined with a propellant actuated depressurization and/or water injection valve is disclosed. The depressurization valve releases pressure from a water cooled, steam producing nuclear reactor when required to insure the safety of the reactor. Depressurization of the reactor pressure vessel enables gravity feeding of supplementary coolant water through the water injection valve to the reactor pressure vessel to prevent damage to the fuel core.

  3. NEUTRONIC REACTOR CONSTRUCTION AND OPERATION

    DOEpatents

    West, J.M.; Weills, J.T.

    1960-03-15

    A method is given for operating a nuclear reactor having a negative coefficient of reactivity to compensate for the change in reactor reactivity due to the burn-up of the xenon peak following start-up of the reactor. When it is desired to start up the reactor within less than 72 hours after shutdown, the temperature of the reactor is lowered prior to start-up, and then gradually raised after start-up.

  4. Thermal-hydraulic interfacing code modules for CANDU reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, W.S.; Gold, M.; Sills, H.

    1997-07-01

    The approach for CANDU reactor safety analysis in Ontario Hydro Nuclear (OHN) and Atomic Energy of Canada Limited (AECL) is presented. Reflecting the unique characteristics of CANDU reactors, the procedure of coupling the thermal-hydraulics, reactor physics and fuel channel/element codes in the safety analysis is described. The experience generated in the Canadian nuclear industry may be useful to other types of reactors in the areas of reactor safety analysis.

  5. 97. ARAIII. ML1 reactor has been moved into GCRE reactor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    97. ARA-III. ML-1 reactor has been moved into GCRE reactor building (ARA-608) for examination of corrosion on its underside and repair. May 24, 1963. Ineel photo no. 63-3485. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  6. NEUTRONIC REACTOR MANIPULATING DEVICE

    DOEpatents

    Ohlinger, L.A.

    1962-08-01

    A cable connecting a control rod in a reactor with a motor outside the reactor for moving the rod, and a helical conduit in the reactor wall, through which the cable passes are described. The helical shape of the conduit prevents the escape of certain harmful radiations from the reactor. (AEC)

  7. 40 CFR 63.1406 - Reactor batch process vent provisions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 11 2011-07-01 2011-07-01 false Reactor batch process vent provisions... § 63.1406 Reactor batch process vent provisions. (a) Emission standards. Owners or operators of reactor... reactor batch process vent located at a new affected source shall control organic HAP emissions by...

  8. 78 FR 73898 - Operator Licensing Examination Standards for Power Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ... Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft NUREG; request for comment. SUMMARY: The U.S..., Revision 10, ``Operator Licensing Examination Standards for Power Reactors.'' DATES: Submit comments [email protected] . Both of the Office of New Reactors; or Timothy Kolb, Office of Nuclear Reactor Regulation, U...

  9. 76 FR 55718 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels The ACRS Subcommittee on Materials, Metallurgy & Reactor...'' for reactor coolant system (RCS) components, as mentioned in 10 CFR 50 Appendix A, GDC-4. The...

  10. 40 CFR 63.1406 - Reactor batch process vent provisions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 11 2010-07-01 2010-07-01 true Reactor batch process vent provisions... § 63.1406 Reactor batch process vent provisions. (a) Emission standards. Owners or operators of reactor... reactor batch process vent located at a new affected source shall control organic HAP emissions by...

  11. 75 FR 58449 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Materials, Metallurgy & Reactor Fuels The ACRS Subcommittee on Materials, Metallurgy & Reactor... would result in a major inconvenience. Dated: September 17, 2010. Antonio Dias, Chief, Reactor Safety...

  12. 151. ARAIII Reactor building (ARA608) Details of reactor pit and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    151. ARA-III Reactor building (ARA-608) Details of reactor pit and instrument plan. Aerojet-general 880-area/GCRE-608-T-19. Date: November 1958. Ineel index code no. 063-0608-25-013-102678. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  13. 10 CFR 72.120 - General considerations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NUCLEAR FUEL, HIGH-LEVEL RADIOACTIVE WASTE, AND REACTOR-RELATED GREATER THAN CLASS C WASTE General Design... reactor-related GTCC waste in an ISFSI or to store spent fuel, high-level radioactive waste, or reactor... be designed to store spent fuel and/or solid reactor-related GTCC waste. (1) Reactor-related GTCC...

  14. ADVANCED REACTIVITY MEASUREMENT FACILITY, TRA660, INTERIOR. REACTOR INSIDE TANK. METAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ADVANCED REACTIVITY MEASUREMENT FACILITY, TRA-660, INTERIOR. REACTOR INSIDE TANK. METAL WORK PLATFORM ABOVE. THE REACTOR WAS IN A SMALL WATER-FILLED POOL. INL NEGATIVE NO. 66-6373. Unknown Photographer, ca. 1966 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  15. 10 CFR 50.30 - Filing of application; oath or affirmation.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Reactor Regulation, Director, Office of New Reactors, or Director, Office of Nuclear Material Safety and... Director, Office of New Reactors, or the Director, Office of Nuclear Reactor Regulation, or the Director..., operating license, early site permit, combined license, or manufacturing license for a nuclear power reactor...

  16. 10 CFR 50.30 - Filing of application; oath or affirmation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Reactor Regulation, Director, Office of New Reactors, or Director, Office of Nuclear Material Safety and... Director, Office of New Reactors, or the Director, Office of Nuclear Reactor Regulation, or the Director..., operating license, early site permit, combined license, or manufacturing license for a nuclear power reactor...

  17. 10 CFR 50.30 - Filing of application; oath or affirmation.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Reactor Regulation, Director, Office of New Reactors, or Director, Office of Nuclear Material Safety and... Director, Office of New Reactors, or the Director, Office of Nuclear Reactor Regulation, or the Director..., operating license, early site permit, combined license, or manufacturing license for a nuclear power reactor...

  18. 10 CFR 50.30 - Filing of application; oath or affirmation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Reactor Regulation, Director, Office of New Reactors, or Director, Office of Nuclear Material Safety and... Director, Office of New Reactors, or the Director, Office of Nuclear Reactor Regulation, or the Director..., operating license, early site permit, combined license, or manufacturing license for a nuclear power reactor...

  19. A Review of Gas-Cooled Reactor Concepts for SDI Applications

    DTIC Science & Technology

    1989-08-01

    710 program .) Wire- Core Reactor (proposed by Rockwell). The wire- core reactor utilizes thin fuel wires woven between spacer wires to form an open...reactor is based on results of developmental studies of nuclear rocket propulsion systems. The reactor core is made up of annular fuel assemblies of...XE Addendum to Volume II. NERVA Fuel Development , Westinghouse Astronuclear Laboratory, TNR-230, July 15’ 1972. J I8- Rover Program Reactor Tests

  20. Computer study of emergency shutdowns of a 60-kilowatt reactor Brayton space power system

    NASA Technical Reports Server (NTRS)

    Tew, R. C.; Jefferies, K. S.

    1974-01-01

    A digital computer study of emergency shutdowns of a 60-kWe reactor Brayton power system was conducted. Malfunctions considered were (1) loss of reactor coolant flow, (2) loss of Brayton system gas flow, (3)turbine overspeed, and (4) a reactivity insertion error. Loss of reactor coolant flow was the most serious malfunction for the reactor. Methods for moderating the reactor transients due to this malfunction are considered.

  1. Function of university reactors in operator licensing training for nuclear utilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wicks, F.

    1985-11-01

    The director of the Division of the US Nuclear Regulatory Commission in generic letter 84-10, dated April 26, 1984, spoke the requirement that applicants for senior reactor operator licenses for power reactors shall have performed then reactor startups. Simulator startups were not acknowledged. Startups performed on a university reactor are acceptable. The content and results of a five-day program combining instruction and experiments with the Rensselaer reactor are summarized.

  2. Numerical Simulations of a 96-rod Polysilicon CVD Reactor

    NASA Astrophysics Data System (ADS)

    Guoqiang, Tang; Cong, Chen; Yifang, Cai; Bing, Zong; Yanguo, Cai; Tihu, Wang

    2018-05-01

    With the rapid development of the photovoltaic industry, pressurized Siemens belljar-type polysilicon CVD reactors have been enlarged from 24 rods to 96 rods in less than 10 years aimed at much greater single-reactor productivity. A CFD model of an industry-scale 96-rod CVD reactor was established to study the internal temperature distribution and the flow field of the reactor. Numerical simulations were carried out and compared with actual growth results from a real CVD reactor. Factors affecting polysilicon depositions such as inlet gas injections, flow field, and temperature distribution in the CVD reactor are studied.

  3. Reactor water cleanup system

    DOEpatents

    Gluntz, D.M.; Taft, W.E.

    1994-12-20

    A reactor water cleanup system includes a reactor pressure vessel containing a reactor core submerged in reactor water. First and second parallel cleanup trains are provided for extracting portions of the reactor water from the pressure vessel, cleaning the extracted water, and returning the cleaned water to the pressure vessel. Each of the cleanup trains includes a heat exchanger for cooling the reactor water, and a cleaner for cleaning the cooled reactor water. A return line is disposed between the cleaner and the pressure vessel for channeling the cleaned water thereto in a first mode of operation. A portion of the cooled water is bypassed around the cleaner during a second mode of operation and returned through the pressure vessel for shutdown cooling. 1 figure.

  4. Characteristics and Dose Levels for Spent Reactor Fuels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coates, Cameron W

    2007-01-01

    Current guidance considers highly radioactive special nuclear materials to be those materials that, unshielded, emit a radiation dose [rate] measured at 1 m which exceeds 100 rem/h. Smaller, less massive fuel assemblies from research reactors can present a challenge from the point of view of self protection because of their size (lower dose, easier to handle) and the desirability of higher enrichments; however, a follow-on study to cross-compare dose trends of research reactors and power reactors was deemed useful to confirm/verify these trends. This paper summarizes the characteristics and dose levels of spent reactor fuels for both research reactors andmore » power reactors and extends previous studies aimed at quantifying expected dose rates from research reactor fuels worldwide.« less

  5. Comparing the new generation accelerator driven subcritical reactor system (ADS) to traditional critical reactors

    NASA Astrophysics Data System (ADS)

    Kemah, Elif; Akkaya, Recep; Tokgöz, Seyit Rıza

    2017-02-01

    In recent years, the accelerator driven subcritical reactors have taken great interest worldwide. The Accelerator Driven System (ADS) has been used to produce neutron in subcritical state by the external proton beam source. These reactors, which are hybrid systems, are important in production of clean and safe energy and conversion of radioactive waste. The ADS with the selection of reliability and robust target materials have been the new generation of fission reactors. In addition, in the ADS Reactors the problems of long-lived radioactive fission products and waste actinides encountered in the fission process of the reactor during incineration can be solved, and ADS has come to the forefront of thorium as fuel for the reactors.

  6. Reactor operation environmental information document

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haselow, J.S.; Price, V.; Stephenson, D.E.

    1989-12-01

    The Savannah River Site (SRS) produces nuclear materials, primarily plutonium and tritium, to meet the requirements of the Department of Defense. These products have been formed in nuclear reactors that were built during 1950--1955 at the SRS. K, L, and P reactors are three of five reactors that have been used in the past to produce the nuclear materials. All three of these reactors discontinued operation in 1988. Currently, intense efforts are being extended to prepare these three reactors for restart in a manner that protects human health and the environment. To document that restarting the reactors will have minimalmore » impacts to human health and the environment, a three-volume Reactor Operations Environmental Impact Document has been prepared. The document focuses on the impacts of restarting the K, L, and P reactors on both the SRS and surrounding areas. This volume discusses the geology, seismology, and subsurface hydrology. 195 refs., 101 figs., 16 tabs.« less

  7. Auxiliary reactor for a hydrocarbon reforming system

    DOEpatents

    Clawson, Lawrence G.; Dorson, Matthew H.; Mitchell, William L.; Nowicki, Brian J.; Bentley, Jeffrey M.; Davis, Robert; Rumsey, Jennifer W.

    2006-01-17

    An auxiliary reactor for use with a reformer reactor having at least one reaction zone, and including a burner for burning fuel and creating a heated auxiliary reactor gas stream, and heat exchanger for transferring heat from auxiliary reactor gas stream and heat transfer medium, preferably two-phase water, to reformer reaction zone. Auxiliary reactor may include first cylindrical wall defining a chamber for burning fuel and creating a heated auxiliary reactor gas stream, the chamber having an inlet end, an outlet end, a second cylindrical wall surrounding first wall and a second annular chamber there between. The reactor being configured so heated auxiliary reactor gas flows out the outlet end and into and through second annular chamber and conduit which is disposed in second annular chamber, the conduit adapted to carry heat transfer medium and being connectable to reformer reaction zone for additional heat exchange.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lister, Tedd E; Parkman, Jacob A; Diaz Aldana, Luis A

    A method of recovering metals from electronic waste comprises providing a powder comprising electronic waste in at least a first reactor and a second reactor and providing an electrolyte comprising at least ferric ions in an electrochemical cell in fluid communication with the first reactor and the second reactor. The method further includes contacting the powders within the first reactor and the second reactor with the electrolyte to dissolve at least one base metal from each reactor into the electrolyte and reduce at least some of the ferric ions to ferrous ions. The ferrous ions are oxidized at an anodemore » of the electrochemical cell to regenerate the ferric ions. The powder within the second reactor comprises a higher weight percent of the at least one base metal than the powder in the first reactor. Additional methods of recovering metals from electronic waste are also described, as well as an apparatus of recovering metals from electronic waste.« less

  9. High-intensity power-resolved radiation imaging of an operational nuclear reactor.

    PubMed

    Beaumont, Jonathan S; Mellor, Matthew P; Villa, Mario; Joyce, Malcolm J

    2015-10-09

    Knowledge of the neutron distribution in a nuclear reactor is necessary to ensure the safe and efficient burnup of reactor fuel. Currently these measurements are performed by in-core systems in what are extremely hostile environments and in most reactor accident scenarios it is likely that these systems would be damaged. Here we present a compact and portable radiation imaging system with the ability to image high-intensity fast-neutron and gamma-ray fields simultaneously. This system has been deployed to image radiation fields emitted during the operation of a TRIGA test reactor allowing a spatial visualization of the internal reactor conditions to be obtained. The imaged flux in each case is found to scale linearly with reactor power indicating that this method may be used for power-resolved reactor monitoring and for the assay of ongoing nuclear criticalities in damaged nuclear reactors.

  10. Exploratory study of several advanced nuclear-MHD power plant systems.

    NASA Technical Reports Server (NTRS)

    Williams, J. R.; Clement, J. D.; Rosa, R. J.; Yang, Y. Y.

    1973-01-01

    In order for efficient multimegawatt closed cycle nuclear-MHD systems to become practical, long-life gas cooled reactors with exit temperatures of about 2500 K or higher must be developed. Four types of nuclear reactors which have the potential of achieving this goal are the NERVA-type solid core reactor, the colloid core (rotating fluidized bed) reactor, the 'light bulb' gas core reactor, and the 'coaxial flow' gas core reactor. Research programs aimed at developing these reactors have progressed rapidly in recent years so that prototype power reactors could be operating by 1980. Three types of power plant systems which use these reactors have been analyzed to determine the operating characteristics, critical parameters and performance of these power plants. Overall thermal efficiencies as high as 80% are projected, using an MHD turbine-compressor cycle with steam bottoming, and slightly lower efficiencies are projected for an MHD motor-compressor cycle.

  11. High-intensity power-resolved radiation imaging of an operational nuclear reactor

    PubMed Central

    Beaumont, Jonathan S.; Mellor, Matthew P.; Villa, Mario; Joyce, Malcolm J.

    2015-01-01

    Knowledge of the neutron distribution in a nuclear reactor is necessary to ensure the safe and efficient burnup of reactor fuel. Currently these measurements are performed by in-core systems in what are extremely hostile environments and in most reactor accident scenarios it is likely that these systems would be damaged. Here we present a compact and portable radiation imaging system with the ability to image high-intensity fast-neutron and gamma-ray fields simultaneously. This system has been deployed to image radiation fields emitted during the operation of a TRIGA test reactor allowing a spatial visualization of the internal reactor conditions to be obtained. The imaged flux in each case is found to scale linearly with reactor power indicating that this method may be used for power-resolved reactor monitoring and for the assay of ongoing nuclear criticalities in damaged nuclear reactors. PMID:26450669

  12. Design and manufacture of a D-shape coil-based toroid-type HTS DC reactor using 2nd generation HTS wire

    NASA Astrophysics Data System (ADS)

    Kim, Kwangmin; Go, Byeong-Soo; Sung, Hae-Jin; Park, Hea-chul; Kim, Seokho; Lee, Sangjin; Jin, Yoon-Su; Oh, Yunsang; Park, Minwon; Yu, In-Keun

    2014-09-01

    This paper describes the design specifications and performance of a real toroid-type high temperature superconducting (HTS) DC reactor. The HTS DC reactor was designed using 2G HTS wires. The HTS coils of the toroid-type DC reactor magnet were made in the form of a D-shape. The target inductance of the HTS DC reactor was 400 mH. The expected operating temperature was under 20 K. The electromagnetic performance of the toroid-type HTS DC reactor magnet was analyzed using the finite element method program. A conduction cooling method was adopted for reactor magnet cooling. Performances of the toroid-type HTS DC reactor were analyzed through experiments conducted under the steady-state and charge conditions. The fundamental design specifications and the data obtained from this research will be applied to the design of a commercial-type HTS DC reactor.

  13. A comparison of the technological effectiveness of dairy wastewater treatment in anaerobic UASB reactor and anaerobic reactor with an innovative design.

    PubMed

    Jedrzejewska-Cicinska, M; Kozak, K; Krzemieniewski, M

    2007-10-01

    The present research was an investigation of the influence of an innovative design of reactor filled with polyethylene (PE) granulate on model dairy wastewater treatment efficiency under anaerobic conditions compared to that obtained in a typical UASB reactor. The experiment was conducted at laboratory scale. An innovative reactor was designed with the reaction chamber inclined 30 degrees in relation to the ground with upward waste flow and was filled with PE granular material. Raw model dairy wastewater was fed to two anaerobic reactors of different design at the organic loading rate of 4 kg COD m(-3)d(-1). Throughout the experiment, a higher removal efficiency of organic compounds was observed in the reactor with an innovative design and it was higher by 7.1% on average than in the UASB reactor. The total suspended solids was lower in the wastewater treated in the anaerobic reactor with the innovative design. Applying a PE granulated filling in the chamber of the innovative reactor contributed to an even distribution of sludge biomass in the reactor, reducing washout of anaerobic sludge biomass from the reaction chamber and giving a higher organic compounds removal efficiency.

  14. Thorium Fuel Utilization Analysis on Small Long Life Reactor for Different Coolant Types

    NASA Astrophysics Data System (ADS)

    Permana, Sidik

    2017-07-01

    A small power reactor and long operation which can be deployed for less population and remote area has been proposed by the IAEA as a small and medium reactor (SMR) program. Beside uranium utilization, it can be used also thorium fuel resources for SMR as a part of optimalization of nuclear fuel as a “partner” fuel with uranium fuel. A small long-life reactor based on thorium fuel cycle for several reactor coolant types and several power output has been evaluated in the present study for 10 years period of reactor operation. Several key parameters are used to evaluate its effect to the reactor performances such as reactor criticality, excess reactivity, reactor burnup achievement and power density profile. Water-cooled types give higher criticality than liquid metal coolants. Liquid metal coolant for fast reactor system gives less criticality especially at beginning of cycle (BOC), which shows liquid metal coolant system obtains almost stable criticality condition. Liquid metal coolants are relatively less excess reactivity to maintain longer reactor operation than water coolants. In addition, liquid metal coolant gives higher achievable burnup than water coolant types as well as higher power density for liquid metal coolants.

  15. Development of toroid-type HTS DC reactor series for HVDC system

    NASA Astrophysics Data System (ADS)

    Kim, Kwangmin; Go, Byeong-Soo; Park, Hea-chul; Kim, Sung-kyu; Kim, Seokho; Lee, Sangjin; Oh, Yunsang; Park, Minwon; Yu, In-Keun

    2015-11-01

    This paper describes design specifications and performance of a toroid-type high-temperature superconducting (HTS) DC reactor. The first phase operation targets of the HTS DC reactor were 400 mH and 400 A. The authors have developed a real HTS DC reactor system during the last three years. The HTS DC reactor was designed using 2G GdBCO HTS wires. The HTS coils of the toroid-type DC reactor magnet were made in the form of a D-shape. The electromagnetic performance of the toroid-type HTS DC reactor magnet was analyzed using the finite element method program. A conduction cooling method was adopted for reactor magnet cooling. The total system has been successfully developed and tested in connection with LCC type HVDC system. Now, the authors are studying a 400 mH, kA class toroid-type HTS DC reactor for the next phase research. The 1500 A class DC reactor system was designed using layered 13 mm GdBCO 2G HTS wire. The expected operating temperature is under 30 K. These fundamental data obtained through both works will usefully be applied to design a real toroid-type HTS DC reactor for grid application.

  16. Experiences in utilization of research reactors in Yugoslavia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Copic, M.; Gabrovsek, Z.; Pop-Jordanov, J.

    1971-06-15

    The nuclear institutes in Yugoslavia possess three research reactors. Since 1958, two heavy-water reactors have been in operation at the 'Boris Kidric' Institute, a zero-power reactor RB and a 6. 5-MW reactor RA. At the Jozef Stefan Institute, a 250-kW TRIGA Mark II reactor has been operating since 1966. All reactors are equipped with the necessary experimental facilities. The main activities based on these reactors are: (1) fundamental research in solid-state and nuclear physics; (2) R and D activities related to nuclear power program; and (3) radioisotope production. In fundamental physics, inelastic neutron scattering and diffraction phenomena are studied bymore » means of the neutron beam tubes and applied to investigations of the structures of solids and liquids. Valuable results are also obtained in n - γ reaction studies. Experiments connected with the fuel -element development program, owing to the characteristics of the existing reactors, are limited to determination of the fuel element parameters, to studies on the purity of uranium, and to a small number of capsule irradiations. All three reactors are also used for the verification of different methods applied in the analysis of power reactors, particularly concerning neutron flux distributions, the optimization of reactor core configurations and the shielding effects. An appreciable irradiation space in the reactors is reserved for isotope production. Fruitful international co-operation has been established in all these activities, on the basis of either bilateral or multilateral arrangements. The paper gives a critical analysis of the utilization of research reactors in a developing country such as Yugoslavia. The investments in and the operational costs of research reactors are compared with the benefits obtained in different areas of reactor application. The impact on the general scientific, technological and educational level in the country is also considered. In particular, an attempt is made ro envisage the role of research reactors in the promotion of nuclear power programs in relation to the size of the program, the competence of domestic industries and the degree of independence where fuel supply is concerned. (author)« less

  17. Nuclear Reactor Physics

    NASA Astrophysics Data System (ADS)

    Stacey, Weston M.

    2001-02-01

    An authoritative textbook and up-to-date professional's guide to basic and advanced principles and practices Nuclear reactors now account for a significant portion of the electrical power generated worldwide. At the same time, the past few decades have seen an ever-increasing number of industrial, medical, military, and research applications for nuclear reactors. Nuclear reactor physics is the core discipline of nuclear engineering, and as the first comprehensive textbook and reference on basic and advanced nuclear reactor physics to appear in a quarter century, this book fills a large gap in the professional literature. Nuclear Reactor Physics is a textbook for students new to the subject, for others who need a basic understanding of how nuclear reactors work, as well as for those who are, or wish to become, specialists in nuclear reactor physics and reactor physics computations. It is also a valuable resource for engineers responsible for the operation of nuclear reactors. Dr. Weston Stacey begins with clear presentations of the basic physical principles, nuclear data, and computational methodology needed to understand both the static and dynamic behaviors of nuclear reactors. This is followed by in-depth discussions of advanced concepts, including extensive treatment of neutron transport computational methods. As an aid to comprehension and quick mastery of computational skills, he provides numerous examples illustrating step-by-step procedures for performing the calculations described and chapter-end problems. Nuclear Reactor Physics is a useful textbook and working reference. It is an excellent self-teaching guide for research scientists, engineers, and technicians involved in industrial, research, and military applications of nuclear reactors, as well as government regulators who wish to increase their understanding of nuclear reactors.

  18. SELF-REGULATING BOILING-WATER NUCLEAR REACTORS

    DOEpatents

    Ransohoff, J.A.; Plawchan, J.D.

    1960-08-16

    A boiling-water reactor was designed which comprises a pressure vessel containing a mass of water, a reactor core submerged within the water, a reflector tank disposed within the reactor, the reflector tank being open at the top to the interior of the pressure vessel, and a surge tank connected to the reflector tank. In operation the reflector level changes as a function of the pressure witoin the reactor so that the reactivity of the reactor is automatically controlled.

  19. REACTOR-FLASH BOILER-FLYWHEEL POWER PLANT

    DOEpatents

    Loeb, E.

    1961-01-17

    A power generator in the form of a flywheel with four reactors positioned about its rim is described. The reactors are so positioned that steam, produced in the reactor, exists tangentially to the flywheel, giving it a rotation. The reactors are incompletely moderated without water. The water enters the flywheel at its axis, under sufficient pressure to force it through the reactors, where it is converted to steam. The fuel consists of parallel twisted ribbons assembled to approximate a cylinder.

  20. System and method for air temperature control in an oxygen transport membrane based reactor

    DOEpatents

    Kelly, Sean M

    2016-09-27

    A system and method for air temperature control in an oxygen transport membrane based reactor is provided. The system and method involves introducing a specific quantity of cooling air or trim air in between stages in a multistage oxygen transport membrane based reactor or furnace to maintain generally consistent surface temperatures of the oxygen transport membrane elements and associated reactors. The associated reactors may include reforming reactors, boilers or process gas heaters.

  1. System and method for temperature control in an oxygen transport membrane based reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kelly, Sean M.

    A system and method for temperature control in an oxygen transport membrane based reactor is provided. The system and method involves introducing a specific quantity of cooling air or trim air in between stages in a multistage oxygen transport membrane based reactor or furnace to maintain generally consistent surface temperatures of the oxygen transport membrane elements and associated reactors. The associated reactors may include reforming reactors, boilers or process gas heaters.

  2. Navy Nuclear-Powered Surface Ships: Background, Issues, and Options for Congress

    DTIC Science & Technology

    2010-09-29

    to design a smaller scale version of a naval pressurized water reactor , or to design a new reactor type potentially using a thorium liquid salt...integrated nuclear power system capable of use on destroyer- sized vessels either using a pressurized water reactor or a thorium liquid salt reactor ...nuclear reactors for Navy surface ships. The text of Section 246 is as follows: SEC. 246. STUDY ON THORIUM -LIQUID FUELED REACTORS FOR NAVAL FORCES

  3. Laboratory instrumentation modernization at the WPI Nuclear Reactor Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1995-01-01

    With partial funding from the Department of Energy (DOE) University Reactor Instrumentation Program several laboratory instruments utilized by students and researchers at the WPI Nuclear Reactor Facility have been upgraded or replaced. Designed and built by General Electric in 1959, the open pool nuclear training reactor at WPI was one of the first such facilities in the nation located on a university campus. Devoted to undergraduate use, the reactor and its related facilities have been since used to train two generations of nuclear engineers and scientists for the nuclear industry. The low power output of the reactor and an ergonomicmore » facility design make it an ideal tool for undergraduate nuclear engineering education and other training. The reactor, its control system, and the associate laboratory equipment are all located in the same room. Over the years, several important milestones have taken place at the WPI reactor. In 1969, the reactor power level was upgraded from 1 kW to 10 kW. The reactor`s Nuclear Regulatory Commission operating license was renewed for 20 years in 1983. In 1988, under DOE Grant No. DE-FG07-86ER75271, the reactor was converted to low-enriched uranium fuel. In 1992, again with partial funding from DOE (Grant No. DE-FG02-90ER12982), the original control console was replaced.« less

  4. Modification of UASB reactor by using CFD simulations for enhanced treatment of municipal sewage.

    PubMed

    Das, Suprotim; Sarkar, Supriya; Chaudhari, Sanjeev

    2018-02-01

    Up-flow anaerobic sludge blanket (UASB) has been in use since last few decades for the treatment of organic wastewaters. However, the performance of UASB reactor is quite low for treatment of low strength wastewaters (LSWs) due to less biogas production leading to poor mixing. In the present research work, a modification was done in the design of UASB to improve mixing of reactor liquid which is important to enhance the reactor performance. The modified UASB (MUASB) reactor was designed by providing a slanted baffle along the height of the reactor having an angle of 5.7° with the vertical wall. A two-dimensional computational fluid dynamics (CFD) simulation of three phase gas-liquid-solid flow in MUASB reactor was performed and compared with conventional UASB reactor. The CFD study indicated better mixing in terms of vorticity magnitude in MUASB reactor as compared to conventional UASB, which was reflected in the reactor performance. The performance of MUASB was compared with conventional UASB reactor for the onsite treatment of domestic sewage as LSW. Around 16% higher total chemical oxygen demand removal efficiency was observed in MUASB reactor as compared to conventional UASB during this study. Therefore, this MUASB model demonstrates a qualitative relationship between mixing and performance during the treatment of LSW. From the study, it seems that MUASB holds promise for field applications.

  5. 10 CFR 50.60 - Acceptance criteria for fracture prevention measures for lightwater nuclear power reactors for...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... lightwater nuclear power reactors for normal operation. 50.60 Section 50.60 Energy NUCLEAR REGULATORY... lightwater nuclear power reactors for normal operation. (a) Except as provided in paragraph (b) of this section, all light-water nuclear power reactors, other than reactor facilities for which the...

  6. 10 CFR 73.60 - Additional requirements for physical protection at nonpower reactors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... nonpower reactors. 73.60 Section 73.60 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION... requirements for physical protection at nonpower reactors. Each nonpower reactor licensee who, pursuant to the... nonpower reactors licensed to operate at or above a power level of 2 megawatts thermal. [38 FR 35430, Dec...

  7. 10 CFR 50.60 - Acceptance criteria for fracture prevention measures for lightwater nuclear power reactors for...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... lightwater nuclear power reactors for normal operation. 50.60 Section 50.60 Energy NUCLEAR REGULATORY... lightwater nuclear power reactors for normal operation. (a) Except as provided in paragraph (b) of this section, all light-water nuclear power reactors, other than reactor facilities for which the...

  8. 10 CFR 73.60 - Additional requirements for physical protection at nonpower reactors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... nonpower reactors. 73.60 Section 73.60 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION... requirements for physical protection at nonpower reactors. Each nonpower reactor licensee who, pursuant to the... nonpower reactors licensed to operate at or above a power level of 2 megawatts thermal. [38 FR 35430, Dec...

  9. 78 FR 26811 - Dow Chemical Company, Dow TRIGA Research Reactor; License Renewal for the Dow Chemical TRIGA...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-08

    ... Research Reactor; License Renewal for the Dow Chemical TRIGA Research Reactor; Supplemental Information and... 20, 2012 (77 FR 42771), ``License Renewal for the Dow Chemical TRIGA Research Reactor,'' to inform... Chemical Company which would authorize continued operation of the Dow TRIGA Research Reactor. The notice...

  10. 10 CFR 140.12 - Amount of financial protection required for other reactors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Amount of financial protection required for other reactors... reactors. (a) Each licensee is required to have and maintain financial protection for each nuclear reactor... of financial protection required for any nuclear reactor under this section be less than $4,500,000...

  11. 10 CFR 140.12 - Amount of financial protection required for other reactors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Amount of financial protection required for other reactors... reactors. (a) Each licensee is required to have and maintain financial protection for each nuclear reactor... of financial protection required for any nuclear reactor under this section be less than $4,500,000...

  12. PBF Reactor Building (PER620). Camera faces north into highbay/reactor pit ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). Camera faces north into high-bay/reactor pit area. Inside from for reactor enclosure is in place. Photographer: John Capek. Date: March 15, 1967. INEEL negative no. 67-1769 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  13. Reactor safety method

    DOEpatents

    Vachon, Lawrence J.

    1980-03-11

    This invention relates to safety means for preventing a gas cooled nuclear reactor from attaining criticality prior to start up in the event the reactor core is immersed in hydrogenous liquid. This is accomplished by coating the inside surface of the reactor coolant channels with a neutral absorbing material that will vaporize at the reactor's operating temperature.

  14. 155. ARAIII Reactor building (ARA608) Details of reactor pit showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    155. ARA-III Reactor building (ARA-608) Details of reactor pit showing tray supports and fuel element storage rack. Aerojet-general 880-area/GCRE-608-MS-2. Date: November 1958. Ineel index code no. 063-0608-40-013-102625. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

  15. World Energy Data System (WENDS). Volume XI. Nuclear fission program summaries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1979-06-01

    Brief management and technical summaries of nuclear fission power programs are presented for nineteen countries. The programs include the following: fuel supply, resource recovery, enrichment, fuel fabrication, light water reactors, heavy water reactors, gas cooled reactors, breeder reactors, research and test reactors, spent fuel processing, waste management, and safety and environment. (JWR)

  16. Breeder Reactors, Understanding the Atom Series.

    ERIC Educational Resources Information Center

    Mitchell, Walter, III; Turner, Stanley E.

    The theory of breeder reactors in relationship to a discussion of fission is presented. Different kinds of reactors are characterized by the cooling fluids used, such as liquid metal, gas, and molten salt. The historical development of breeder reactors over the past twenty-five years includes specific examples of reactors. The location and a brief…

  17. 10 CFR 140.12 - Amount of financial protection required for other reactors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... reactors. (a) Each licensee is required to have and maintain financial protection for each nuclear reactor... of financial protection required for any nuclear reactor under this section be less than $4,500,000... chapter to operate two or more nuclear reactors at the same location, the total financial protection...

  18. 10 CFR 2.103 - Action on applications for byproduct, source, special nuclear material, facility and operator...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of Federal and..., Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of Nuclear... of this chapter, see § 2.106(d). (b) If the Director, Office of Nuclear Reactor Regulation, Director...

  19. 10 CFR 140.12 - Amount of financial protection required for other reactors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... reactors. (a) Each licensee is required to have and maintain financial protection for each nuclear reactor... of financial protection required for any nuclear reactor under this section be less than $4,500,000... chapter to operate two or more nuclear reactors at the same location, the total financial protection...

  20. 10 CFR 140.12 - Amount of financial protection required for other reactors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... reactors. (a) Each licensee is required to have and maintain financial protection for each nuclear reactor... of financial protection required for any nuclear reactor under this section be less than $4,500,000... chapter to operate two or more nuclear reactors at the same location, the total financial protection...

  1. 10 CFR 2.103 - Action on applications for byproduct, source, special nuclear material, facility and operator...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of Federal and..., Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of Nuclear... of this chapter, see § 2.106(d). (b) If the Director, Office of Nuclear Reactor Regulation, Director...

  2. Computer model of catalytic combustion/Stirling engine heater head

    NASA Technical Reports Server (NTRS)

    Chu, E. K.; Chang, R. L.; Tong, H.

    1981-01-01

    The basic Acurex HET code was modified to analyze specific problems for Stirling engine heater head applications. Specifically, the code can model: an adiabatic catalytic monolith reactor, an externally cooled catalytic cylindrical reactor/flat plate reactor, a coannular tube radiatively cooled reactor, and a monolithic reactor radiating to upstream and downstream heat exchangers.

  3. Analysis of the Gas Core Actinide Transmutation Reactor (GCATR)

    NASA Technical Reports Server (NTRS)

    Clement, J. D.; Rust, J. H.

    1977-01-01

    Design power plant studies were carried out for two applications of the plasma core reactor: (1) As a breeder reactor, (2) As a reactor able to transmute actinides effectively. In addition to the above applications the reactor produced electrical power with a high efficiency. A reactor subsystem was designed for each of the two applications. For the breeder reactor, neutronics calculations were carried out for a U-233 plasma core with a molten salt breeding blanket. A reactor was designed with a low critical mass (less than a few hundred kilograms U-233) and a breeding ratio of 1.01. The plasma core actinide transmutation reactor was designed to transmute the nuclear waste from conventional LWR's. The spent fuel is reprocessed during which 100% of Np, Am, Cm, and higher actinides are separated from the other components. These actinides are then manufactured as oxides into zirconium clad fuel rods and charged as fuel assemblies in the reflector region of the plasma core actinide transmutation reactor. In the equilibrium cycle, about 7% of the actinides are directly fissioned away, while about 31% are removed by reprocessing.

  4. MONTE CARLO SIMULATIONS OF PERIODIC PULSED REACTOR WITH MOVING GEOMETRY PARTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cao, Yan; Gohar, Yousry

    2015-11-01

    In a periodic pulsed reactor, the reactor state varies periodically from slightly subcritical to slightly prompt supercritical for producing periodic power pulses. Such periodic state change is accomplished by a periodic movement of specific reactor parts, such as control rods or reflector sections. The analysis of such reactor is difficult to perform with the current reactor physics computer programs. Based on past experience, the utilization of the point kinetics approximations gives considerable errors in predicting the magnitude and the shape of the power pulse if the reactor has significantly different neutron life times in different zones. To accurately simulate themore » dynamics of this type of reactor, a Monte Carlo procedure using the transfer function TRCL/TR of the MCNP/MCNPX computer programs is utilized to model the movable reactor parts. In this paper, two algorithms simulating the geometry part movements during a neutron history tracking have been developed. Several test cases have been developed to evaluate these procedures. The numerical test cases have shown that the developed algorithms can be utilized to simulate the reactor dynamics with movable geometry parts.« less

  5. Pressurized fluidized bed reactor

    DOEpatents

    Isaksson, J.

    1996-03-19

    A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine. 1 fig.

  6. Pressurized fluidized bed reactor

    DOEpatents

    Isaksson, Juhani

    1996-01-01

    A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine.

  7. Reactor vibration reduction based on giant magnetostrictive materials

    NASA Astrophysics Data System (ADS)

    Rongge, Yan; Weiying, Liu; Yuechao, Wu; Menghua, Duan; Xiaohong, Zhang; Lihua, Zhu; Ling, Weng; Ying, Sun

    2017-05-01

    The vibration of reactors not only produces noise pollution, but also affects the safe operation of reactors. Giant magnetostrictive materials can generate huge expansion and shrinkage deformation in a magnetic field. With the principle of mutual offset between the giant magnetostrictive force produced by the giant magnetostrictive material and the original vibration force of the reactor, the vibration of the reactor can be reduced. In this paper, magnetization and magnetostriction characteristics in silicon steel and the giant magnetostrictive material are measured, respectively. According to the presented magneto-mechanical coupling model including the electromagnetic force and the magnetostrictive force, reactor vibration is calculated. By comparing the vibration of the reactor with different inserted materials in the air gaps between the reactor cores, the vibration reduction effectiveness of the giant magnetostrictive material is validated.

  8. Preliminary analysis of loss-of-coolant accident in Fukushima nuclear accident

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Su'ud, Zaki; Anshari, Rio

    Loss-of-Coolant Accident (LOCA) in Boiling Water Reactor (BWR) especially on Fukushima Nuclear Accident will be discussed in this paper. The Tohoku earthquake triggered the shutdown of nuclear power reactors at Fukushima Nuclear Power station. Though shutdown process has been completely performed, cooling process, at much smaller level than in normal operation, is needed to remove decay heat from the reactor core until the reactor reach cold-shutdown condition. If LOCA happen at this condition, it will cause the increase of reactor fuel and other core temperatures and can lead to reactor core meltdown and exposure of radioactive material to the environmentmore » such as in the Fukushima Dai Ichi nuclear accident case. In this study numerical simulation has been performed to calculate pressure composition, water level and temperature distribution on reactor during this accident. There are two coolant regulating system that operational on reactor unit 1 at this accident, Isolation Condensers (IC) system and Safety Relief Valves (SRV) system. Average mass flow of steam to the IC system in this event is 10 kg/s and could keep reactor core from uncovered about 3,2 hours and fully uncovered in 4,7 hours later. There are two coolant regulating system at operational on reactor unit 2, Reactor Core Isolation Condenser (RCIC) System and Safety Relief Valves (SRV). Average mass flow of coolant that correspond this event is 20 kg/s and could keep reactor core from uncovered about 73 hours and fully uncovered in 75 hours later. There are three coolant regulating system at operational on reactor unit 3, Reactor Core Isolation Condenser (RCIC) system, High Pressure Coolant Injection (HPCI) system and Safety Relief Valves (SRV). Average mass flow of water that correspond this event is 15 kg/s and could keep reactor core from uncovered about 37 hours and fully uncovered in 40 hours later.« less

  9. Preliminary analysis of loss-of-coolant accident in Fukushima nuclear accident

    NASA Astrophysics Data System (ADS)

    Su'ud, Zaki; Anshari, Rio

    2012-06-01

    Loss-of-Coolant Accident (LOCA) in Boiling Water Reactor (BWR) especially on Fukushima Nuclear Accident will be discussed in this paper. The Tohoku earthquake triggered the shutdown of nuclear power reactors at Fukushima Nuclear Power station. Though shutdown process has been completely performed, cooling process, at much smaller level than in normal operation, is needed to remove decay heat from the reactor core until the reactor reach cold-shutdown condition. If LOCA happen at this condition, it will cause the increase of reactor fuel and other core temperatures and can lead to reactor core meltdown and exposure of radioactive material to the environment such as in the Fukushima Dai Ichi nuclear accident case. In this study numerical simulation has been performed to calculate pressure composition, water level and temperature distribution on reactor during this accident. There are two coolant regulating system that operational on reactor unit 1 at this accident, Isolation Condensers (IC) system and Safety Relief Valves (SRV) system. Average mass flow of steam to the IC system in this event is 10 kg/s and could keep reactor core from uncovered about 3,2 hours and fully uncovered in 4,7 hours later. There are two coolant regulating system at operational on reactor unit 2, Reactor Core Isolation Condenser (RCIC) System and Safety Relief Valves (SRV). Average mass flow of coolant that correspond this event is 20 kg/s and could keep reactor core from uncovered about 73 hours and fully uncovered in 75 hours later. There are three coolant regulating system at operational on reactor unit 3, Reactor Core Isolation Condenser (RCIC) system, High Pressure Coolant Injection (HPCI) system and Safety Relief Valves (SRV). Average mass flow of water that correspond this event is 15 kg/s and could keep reactor core from uncovered about 37 hours and fully uncovered in 40 hours later.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wichman, K.; Tsao, J.; Mayfield, M.

    The regulatory application of leak before break (LBB) for operating and advanced reactors in the U.S. is described. The U.S. Nuclear Regulatory Commission (NRC) has approved the application of LBB for six piping systems in operating reactors: reactor coolant system primary loop piping, pressurizer surge, safety injection accumulator, residual heat removal, safety injection, and reactor coolant loop bypass. The LBB concept has also been applied in the design of advanced light water reactors. LBB applications, and regulatory considerations, for pressurized water reactors and advanced light water reactors are summarized in this paper. Technology development for LBB performed by the NRCmore » and the International Piping Integrity Research Group is also briefly summarized.« less

  11. Solution of heat removal from nuclear reactors by natural convection

    NASA Astrophysics Data System (ADS)

    Zitek, Pavel; Valenta, Vaclav

    2014-03-01

    This paper summarizes the basis for the solution of heat removal by natural convection from both conventional nuclear reactors and reactors with fuel flowing coolant (such as reactors with molten fluoride salts MSR).The possibility of intensification of heat removal through gas lift is focused on. It might be used in an MSR (Molten Salt Reactor) for cleaning the salt mixture of degassed fission products and therefore eliminating problems with iodine pitting. Heat removal by natural convection and its intensification increases significantly the safety of nuclear reactors. Simultaneously the heat removal also solves problems with lifetime of pumps in the primary circuit of high-temperature reactors.

  12. Imaging Fukushima Daiichi reactors with muons

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miyadera, Haruo; Borozdin, Konstantin N.; Greene, Steve J.

    2013-05-15

    A study of imaging the Fukushima Daiichi reactors with cosmic-ray muons to assess the damage to the reactors is presented. Muon scattering imaging has high sensitivity for detecting uranium fuel and debris even through thick concrete walls and a reactor pressure vessel. Technical demonstrations using a reactor mockup, detector radiation test at Fukushima Daiichi, and simulation studies have been carried out. These studies establish feasibility for the reactor imaging. A few months of measurement will reveal the spatial distribution of the reactor fuel. The muon scattering technique would be the best and probably the only way for Fukushima Daiichi tomore » make this determination in the near future.« less

  13. Imaging Fukushima Daiichi reactors with muons

    NASA Astrophysics Data System (ADS)

    Miyadera, Haruo; Borozdin, Konstantin N.; Greene, Steve J.; Lukić, Zarija; Masuda, Koji; Milner, Edward C.; Morris, Christopher L.; Perry, John O.

    2013-05-01

    A study of imaging the Fukushima Daiichi reactors with cosmic-ray muons to assess the damage to the reactors is presented. Muon scattering imaging has high sensitivity for detecting uranium fuel and debris even through thick concrete walls and a reactor pressure vessel. Technical demonstrations using a reactor mockup, detector radiation test at Fukushima Daiichi, and simulation studies have been carried out. These studies establish feasibility for the reactor imaging. A few months of measurement will reveal the spatial distribution of the reactor fuel. The muon scattering technique would be the best and probably the only way for Fukushima Daiichi to make this determination in the near future.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fitzpatrick, F.C.; Gray, D.D.; Hyndman, J.R.

    The thermal, ecological, and social impacts of a 40-reactor NEC are compared to impacts from four 10-reactor NECs and ten 4-reactor power plants. The comparison was made for surrogate sites in western Tennessee. The surrogate site for the 40-reactor NEC is located on Kentucky Lake. A layout is postulated for ten clusters of four reactors each with 2.5-mile spacing between clusters. The plants use natural-draft cooling towers. A transmission system is proposed for delivering the power (48,000 MW) to five load centers. Comparable transmission systems are proposed for the 10-reactor NECs and the 4-reactor dispersed sites delivering power to themore » same load centers. (auth)« less

  15. Digital computer study of nuclear reactor thermal transients during startup of 60-kWe Brayton power conversion system

    NASA Technical Reports Server (NTRS)

    Jefferies, K. S.; Tew, R. C.

    1974-01-01

    A digital computer study was made of reactor thermal transients during startup of the Brayton power conversion loop of a 60-kWe reactor Brayton power system. A startup procedure requiring the least Brayton system complication was tried first; this procedure caused violations of design limits on key reactor variables. Several modifications of this procedure were then found which caused no design limit violations. These modifications involved: (1) using a slower rate of increase in gas flow; (2) increasing the initial reactor power level to make the reactor respond faster; and (3) appropriate reactor control drum manipulation during the startup transient.

  16. Hybrid adsorptive membrane reactor

    NASA Technical Reports Server (NTRS)

    Tsotsis, Theodore T. (Inventor); Sahimi, Muhammad (Inventor); Fayyaz-Najafi, Babak (Inventor); Harale, Aadesh (Inventor); Park, Byoung-Gi (Inventor); Liu, Paul K. T. (Inventor)

    2011-01-01

    A hybrid adsorbent-membrane reactor in which the chemical reaction, membrane separation, and product adsorption are coupled. Also disclosed are a dual-reactor apparatus and a process using the reactor or the apparatus.

  17. Hybrid adsorptive membrane reactor

    DOEpatents

    Tsotsis, Theodore T [Huntington Beach, CA; Sahimi, Muhammad [Altadena, CA; Fayyaz-Najafi, Babak [Richmond, CA; Harale, Aadesh [Los Angeles, CA; Park, Byoung-Gi [Yeosu, KR; Liu, Paul K. T. [Lafayette Hill, PA

    2011-03-01

    A hybrid adsorbent-membrane reactor in which the chemical reaction, membrane separation, and product adsorption are coupled. Also disclosed are a dual-reactor apparatus and a process using the reactor or the apparatus.

  18. Neutron Fluence And DPA Rate Analysis In Pebble-Bed HTR Reactor Vessel Using MCNP

    NASA Astrophysics Data System (ADS)

    Hamzah, Amir; Suwoto; Rohanda, Anis; Adrial, Hery; Bakhri, Syaiful; Sunaryo, Geni Rina

    2018-02-01

    In the Pebble-bed HTR reactor, the distance between the core and the reactor vessel is very close and the media inside are carbon and He gas. Neutron moderation capability of graphite material is theoretically lower than that of water-moderated reactors. Thus, it is estimated much more the fast neutrons will reach the reactor vessel. The fast neutron collisions with the atoms in the reactor vessel will result in radiation damage and could be reducing the vessel life. The purpose of this study was to obtain the magnitude of neutron fluence in the Pebble-bed HTR reactor vessel. Neutron fluence calculations in the pebble-bed HTR reactor vessel were performed using the MCNP computer program. By determining the tally position, it can be calculated flux, spectrum and neutron fluence in the position of Pebble-bed HTR reactor vessel. The calculations results of total neutron flux and fast neutron flux in the reactor vessel of 1.82x108 n/cm2/s and 1.79x108 n/cm2/s respectively. The fast neutron fluence in the reactor vessel is 3.4x1017 n/cm2 for 60 years reactor operation. Radiation damage in stainless steel material caused by high-energy neutrons (> 1.0 MeV) will occur when it has reached the neutron flux level of 1.0x1024 n/cm2. The neutron fluence results show that there is no radiation damage in the Pebble-bed HTR reactor vessel, so it is predicted that it will be safe to operate at least for 60 years.

  19. Reactor performances and microbial communities of biogas reactors: effects of inoculum sources.

    PubMed

    Han, Sheng; Liu, Yafeng; Zhang, Shicheng; Luo, Gang

    2016-01-01

    Anaerobic digestion is a very complex process that is mediated by various microorganisms, and the understanding of the microbial community assembly and its corresponding function is critical in order to better control the anaerobic process. The present study investigated the effect of different inocula on the microbial community assembly in biogas reactors treating cellulose with various inocula, and three parallel biogas reactors with the same inoculum were also operated in order to reveal the reproducibility of both microbial communities and functions of the biogas reactors. The results showed that the biogas production, volatile fatty acid (VFA) concentrations, and pH were different for the biogas reactors with different inocula, and different steady-state microbial community patterns were also obtained in different biogas reactors as reflected by Bray-Curtis similarity matrices and taxonomic classification. It indicated that inoculum played an important role in shaping the microbial communities of biogas reactor in the present study, and the microbial community assembly in biogas reactor did not follow the niche-based ecology theory. Furthermore, it was found that the microbial communities and reactor performances of parallel biogas reactors with the same inoculum were different, which could be explained by the neutral-based ecology theory and stochastic factors should played important roles in the microbial community assembly in the biogas reactors. The Bray-Curtis similarity matrices analysis suggested that inoculum affected more on the microbial community assembly compared to stochastic factors, since the samples with different inocula had lower similarity (10-20 %) compared to the samples from the parallel biogas reactors (30 %).

  20. A novel plant protection strategy for transient reactors

    NASA Astrophysics Data System (ADS)

    Bhattacharyya, Samit K.; Lipinski, Walter C.; Hanan, Nelson A.

    The present plant protection system (PPS) has been defined for use in the TREAT-upgrade (TU) reactor for controlled transient operation of reactor-fuel behavior testing under simulated reactor-accident conditions. A PPS with energy-dependent trip set points lowered worst-case clad temperatures by as much as 180 K, relative to the use of conventional fixed-level trip set points. The multilayered multilevel protection strategy represents the state-of-the-art in terrestrial transient reactor protection systems, and should be applicable to multi-MW space reactors.

  1. Nuclear Energy Policy

    DTIC Science & Technology

    2009-12-10

    Small Modular Reactors Rising cost estimates for large conventional nuclear power plants—widely projected to be $6 billion or more—have contributed to growing interest in proposals for smaller, modular reactors. Ranging from about 40 to 350 megawatts of electrical capacity, such reactors would be only a fraction of the size of current commercial reactors. Several modular reactors would be installed together to make up a power block with a single control room, under most concepts. Modular reactor concepts would use a variety of technologies,

  2. Research and proposal on selective catalytic reduction reactor optimization for industrial boiler.

    PubMed

    Yang, Yiming; Li, Jian; He, Hong

    2017-08-24

    The advanced computational fluid dynamics (CFD) software STAR-CCM+ was used to simulate a denitrification (De-NOx) project for a boiler in this paper, and the simulation result was verified based on a physical model. Two selective catalytic reduction (SCR) reactors were developed: reactor 1 was optimized and reactor 2 was developed based on reactor 1. Various indicators, including gas flow field, ammonia concentration distribution, temperature distribution, gas incident angle, and system pressure drop were analyzed. The analysis indicated that reactor 2 was of outstanding performance and could simplify developing greatly. Ammonia injection grid (AIG), the core component of the reactor, was studied; three AIGs were developed and their performances were compared and analyzed. The result indicated that AIG 3 was of the best performance. The technical indicators were proposed for SCR reactor based on the study. Flow filed distribution, gas incident angle, and temperature distribution are subjected to SCR reactor shape to a great extent, and reactor 2 proposed in this paper was of outstanding performance; ammonia concentration distribution is subjected to ammonia injection grid (AIG) shape, and AIG 3 could meet the technical indicator of ammonia concentration without mounting ammonia mixer. The developments above on the reactor and the AIG are both of great application value and social efficiency.

  3. REACTOR PHYSICS MODELING OF SPENT RESEARCH REACTOR FUEL FOR TECHNICAL NUCLEAR FORENSICS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nichols, T.; Beals, D.; Sternat, M.

    2011-07-18

    Technical nuclear forensics (TNF) refers to the collection, analysis and evaluation of pre- and post-detonation radiological or nuclear materials, devices, and/or debris. TNF is an integral component, complementing traditional forensics and investigative work, to help enable the attribution of discovered radiological or nuclear material. Research is needed to improve the capabilities of TNF. One research area of interest is determining the isotopic signatures of research reactors. Research reactors are a potential source of both radiological and nuclear material. Research reactors are often the least safeguarded type of reactor; they vary greatly in size, fuel type, enrichment, power, and burn-up. Manymore » research reactors are fueled with highly-enriched uranium (HEU), up to {approx}93% {sup 235}U, which could potentially be used as weapons material. All of them have significant amounts of radiological material with which a radioactive dispersal device (RDD) could be built. Therefore, the ability to attribute if material originated from or was produced in a specific research reactor is an important tool in providing for the security of the United States. Currently there are approximately 237 operating research reactors worldwide, another 12 are in temporary shutdown and 224 research reactors are reported as shut down. Little is currently known about the isotopic signatures of spent research reactor fuel. An effort is underway at Savannah River National Laboratory (SRNL) to analyze spent research reactor fuel to determine these signatures. Computer models, using reactor physics codes, are being compared to the measured analytes in the spent fuel. This allows for improving the reactor physics codes in modeling research reactors for the purpose of nuclear forensics. Currently the Oak Ridge Research reactor (ORR) is being modeled and fuel samples are being analyzed for comparison. Samples of an ORR spent fuel assembly were taken by SRNL for analytical and radiochemical analysis. The fuel assembly was modeled using MONTEBURNS(MCNP5/ ORIGEN2.2) and MCNPX/CINDER90. The results from the models have been compared to each other and to the measured data.« less

  4. 10 CFR Appendix A to Part 110 - Illustrative List of Nuclear Reactor Equipment Under NRC Export Licensing Authority

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Illustrative List of Nuclear Reactor Equipment Under NRC... List of Nuclear Reactor Equipment Under NRC Export Licensing Authority Note—A nuclear reactor basically includes the items within or attached directly to the reactor vessel, the equipment which controls the...

  5. 78 FR 20959 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-08

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Advanced Boiling Water Reactor The ACRS Subcommittee on Advanced Boiling Water Reactor (ABWR... Committee on Reactor Safeguards. [FR Doc. 2013-08131 Filed 4-5-13; 8:45 am] BILLING CODE 7590-01-P ...

  6. 10 CFR Appendix A to Part 110 - Illustrative List of Nuclear Reactor Equipment Under NRC Export Licensing Authority

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Illustrative List of Nuclear Reactor Equipment Under NRC... List of Nuclear Reactor Equipment Under NRC Export Licensing Authority Note—A nuclear reactor basically includes the items within or attached directly to the reactor vessel, the equipment which controls the...

  7. 10 CFR 50.46 - Acceptance criteria for emergency core cooling systems for light-water nuclear power reactors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... light-water nuclear power reactors. 50.46 Section 50.46 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... reactors. (a)(1)(i) Each boiling or pressurized light-water nuclear power reactor fueled with uranium oxide... behavior of the reactor system during a loss-of-coolant accident. Comparisons to applicable experimental...

  8. NEUTRONIC REACTOR

    DOEpatents

    Fermi, E.; Zinn, W.H.; Anderson, H.L.

    1958-09-16

    Means are presenied for increasing the reproduction ratio of a gaphite- moderated neutronic reactor by diminishing the neutron loss due to absorption or capture by gaseous impurities within the reactor. This means comprised of a fluid-tight casing or envelope completely enclosing the reactor and provided with a valve through which the casing, and thereby the reactor, may be evacuated of atmospheric air.

  9. 76 FR 70331 - List of Approved Spent Fuel Storage Casks: MAGNASTOR ® System, Revision 2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... various boron-10 areal densities for use with Pressurized Water Reactor and Boiling Water Reactor baskets... add various boron-10 areal densities for use with Pressurized Water Reactor and Boiling Water Reactor....1.1 to add various boron-10 areal densities for use with Pressurized Water Reactor and Boiling Water...

  10. 10 CFR 50.46 - Acceptance criteria for emergency core cooling systems for light-water nuclear power reactors.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... light-water nuclear power reactors. 50.46 Section 50.46 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... reactors. (a)(1)(i) Each boiling or pressurized light-water nuclear power reactor fueled with uranium oxide... evaluation model. This section does not apply to a nuclear power reactor facility for which the...

  11. 10 CFR Appendix A to Part 110 - Illustrative List of Nuclear Reactor Equipment Under NRC Export Licensing Authority

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Illustrative List of Nuclear Reactor Equipment Under NRC... List of Nuclear Reactor Equipment Under NRC Export Licensing Authority Note: A nuclear reactor... core of a nuclear reactor and capable of withstanding the operating pressure of the primary coolant. (2...

  12. 10 CFR 50.46 - Acceptance criteria for emergency core cooling systems for light-water nuclear power reactors.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... light-water nuclear power reactors. 50.46 Section 50.46 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... reactors. (a)(1)(i) Each boiling or pressurized light-water nuclear power reactor fueled with uranium oxide... evaluation model. This section does not apply to a nuclear power reactor facility for which the...

  13. 10 CFR 50.46 - Acceptance criteria for emergency core cooling systems for light-water nuclear power reactors.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... light-water nuclear power reactors. 50.46 Section 50.46 Energy NUCLEAR REGULATORY COMMISSION DOMESTIC... reactors. (a)(1)(i) Each boiling or pressurized light-water nuclear power reactor fueled with uranium oxide... evaluation model. This section does not apply to a nuclear power reactor facility for which the...

  14. NEUTRONIC REACTOR

    DOEpatents

    Wigner, E.P.

    1958-04-22

    A nuclear reactor for isotope production is described. This reactor is designed to provide a maximum thermal neutron flux in a region adjacent to the periphery of the reactor rather than in the center of the reactor. The core of the reactor is generally centrally located with respect tn a surrounding first reflector, constructed of beryllium. The beryllium reflector is surrounded by a second reflector, constructed of graphite, which, in tune, is surrounded by a conventional thermal shield. Water is circulated through the core and the reflector and functions both as a moderator and a coolant. In order to produce a greatsr maximum thermal neutron flux adjacent to the periphery of the reactor rather than in the core, the reactor is designed so tbat the ratio of neutron scattering cross section to neutron absorption cross section averaged over all of the materials in the reflector is approximately twice the ratio of neutron scattering cross section to neutron absorption cross section averaged over all of the material of the core of the reactor.

  15. Next generation fuel irradiation capability in the High Flux Reactor Petten

    NASA Astrophysics Data System (ADS)

    Fütterer, Michael A.; D'Agata, Elio; Laurie, Mathias; Marmier, Alain; Scaffidi-Argentina, Francesco; Raison, Philippe; Bakker, Klaas; de Groot, Sander; Klaassen, Frodo

    2009-07-01

    This paper describes selected equipment and expertise on fuel irradiation testing at the High Flux Reactor (HFR) in Petten, The Netherlands. The reactor went critical in 1961 and holds an operating license up to at least 2015. While HFR has initially focused on Light Water Reactor fuel and materials, it also played a decisive role since the 1970s in the German High Temperature Reactor (HTR) development program. A variety of tests related to fast reactor development in Europe were carried out for next generation fuel and materials, in particular for Very High Temperature Reactor (V/HTR) fuel, fuel for closed fuel cycles (U-Pu and Th-U fuel cycle) and transmutation, as well as for other innovative fuel types. The HFR constitutes a significant European infrastructure tool for the development of next generation reactors. Experimental facilities addressed include V/HTR fuel tests, a coated particle irradiation rig, and tests on fast reactor, transmutation and thorium fuel. The rationales for these tests are given, results are provided and further work is outlined.

  16. Using thermal balance model to determine optimal reactor volume and insulation material needed in a laboratory-scale composting reactor.

    PubMed

    Wang, Yongjiang; Pang, Li; Liu, Xinyu; Wang, Yuansheng; Zhou, Kexun; Luo, Fei

    2016-04-01

    A comprehensive model of thermal balance and degradation kinetics was developed to determine the optimal reactor volume and insulation material. Biological heat production and five channels of heat loss were considered in the thermal balance model for a representative reactor. Degradation kinetics was developed to make the model applicable to different types of substrates. Simulation of the model showed that the internal energy accumulation of compost was the significant heat loss channel, following by heat loss through reactor wall, and latent heat of water evaporation. Lower proportion of heat loss occurred through the reactor wall when the reactor volume was larger. Insulating materials with low densities and low conductive coefficients were more desirable for building small reactor systems. Model developed could be used to determine the optimal reactor volume and insulation material needed before the fabrication of a lab-scale composting system. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Utilization of Stop-flow Micro-tubing Reactors for the Development of Organic Transformations.

    PubMed

    Toh, Ren Wei; Li, Jie Sheng; Wu, Jie

    2018-01-04

    A new reaction screening technology for organic synthesis was recently demonstrated by combining elements from both continuous micro-flow and conventional batch reactors, coined stop-flow micro-tubing (SFMT) reactors. In SFMT, chemical reactions that require high pressure can be screened in parallel through a safer and convenient way. Cross-contamination, which is a common problem in reaction screening for continuous flow reactors, is avoided in SFMT. Moreover, the commercially available light-permeable micro-tubing can be incorporated into SFMT, serving as an excellent choice for light-mediated reactions due to a more effective uniform light exposure, compared to batch reactors. Overall, the SFMT reactor system is similar to continuous flow reactors and more superior than batch reactors for reactions that incorporate gas reagents and/or require light-illumination, which enables a simple but highly efficient reaction screening system. Furthermore, any successfully developed reaction in the SFMT reactor system can be conveniently translated to continuous-flow synthesis for large scale production.

  18. Employing ISRU Models to Improve Hardware Design

    NASA Technical Reports Server (NTRS)

    Linne, Diane L.

    2010-01-01

    An analytical model for hydrogen reduction of regolith was used to investigate the effects of several key variables on the energy and mass performance of reactors for a lunar in-situ resource utilization oxygen production plant. Reactor geometry, reaction time, number of reactors, heat recuperation, heat loss, and operating pressure were all studied to guide hardware designers who are developing future prototype reactors. The effects of heat recuperation where the incoming regolith is pre-heated by the hot spent regolith before transfer was also investigated for the first time. In general, longer reaction times per batch provide a lower overall energy, but also result in larger and heavier reactors. Three reactors with long heat-up times results in similar energy requirements as a two-reactor system with all other parameters the same. Three reactors with heat recuperation results in energy reductions of 20 to 40 percent compared to a three-reactor system with no heat recuperation. Increasing operating pressure can provide similar energy reductions as heat recuperation for the same reaction times.

  19. NEUTRONIC REACTOR SYSTEM

    DOEpatents

    Treshow, M.

    1959-02-10

    A reactor system incorporating a reactor of the heterogeneous boiling water type is described. The reactor is comprised essentially of a core submerged adwater in the lower half of a pressure vessel and two distribution rings connected to a source of water are disposed within the pressure vessel above the reactor core, the lower distribution ring being submerged adjacent to the uppcr end of the reactor core and the other distribution ring being located adjacent to the top of the pressure vessel. A feed-water control valve, responsive to the steam demand of the load, is provided in the feedwater line to the distribution rings and regulates the amount of feed water flowing to each distribution ring, the proportion of water flowing to the submerged distribution ring being proportional to the steam demand of the load. This invention provides an automatic means exterior to the reactor to control the reactivity of the reactor over relatively long periods of time without relying upon movement of control rods or of other moving parts within the reactor structure.

  20. Oak Ridge National Laboratory Support of Non-light Water Reactor Technologies: Capabilities Assessment for NRC Near-term Implementation Action Plans for Non-light Water Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Belles, Randy; Jain, Prashant K.; Powers, Jeffrey J.

    The Oak Ridge National Laboratory (ORNL) has a rich history of support for light water reactor (LWR) and non-LWR technologies. The ORNL history involves operation of 13 reactors at ORNL including the graphite reactor dating back to World War II, two aqueous homogeneous reactors, two molten salt reactors (MSRs), a fast-burst health physics reactor, and seven LWRs. Operation of the High Flux Isotope Reactor (HFIR) has been ongoing since 1965. Expertise exists amongst the ORNL staff to provide non-LWR training; support evaluation of non-LWR licensing and safety issues; perform modeling and simulation using advanced computational tools; run laboratory experiments usingmore » equipment such as the liquid salt component test facility; and perform in-depth fuel performance and thermal-hydraulic technology reviews using a vast suite of computer codes and tools. Summaries of this expertise are included in this paper.« less

  1. The IRIS Spool-Type Reactor Coolant Pump

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kujawski, J.M.; Kitch, D.M.; Conway, L.E.

    2002-07-01

    IRIS (International Reactor Innovative and Secure) is a light water cooled, 335 MWe power reactor which is being designed by an international consortium as part of the US DOE NERI Program. IRIS features an integral reactor vessel that contains all the major reactor coolant system components including the reactor core, the coolant pumps, the steam generators and the pressurizer. This integral design approach eliminates the large coolant loop piping, and thus eliminates large loss-of-coolant accidents (LOCAs) as well as the individual component pressure vessels and supports. In addition, IRIS is being designed with a long life core and enhanced safetymore » to address the requirements defined by the US DOE for Generation IV reactors. One of the innovative features of the IRIS design is the adoption of a reactor coolant pump (called 'spool' pump) which is completely contained inside the reactor vessel. Background, status and future developments of the IRIS spool pump are presented in this paper. (authors)« less

  2. 10 CFR 171.3 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... holding an operating license for a power reactor, test reactor or research reactor issued under part 50 of... authorizes operation of a power reactor. The regulations in this part also apply to any person holding a...

  3. Advanced Test Reactor Tour

    ScienceCinema

    Miley, Don

    2017-12-21

    The Advanced Test Reactor at Idaho National Laboratory is the foremost nuclear materials test reactor in the world. This virtual tour describes the reactor, how experiments are conducted, and how spent nuclear fuel is handled and stored.

  4. Looking Southwest at Reactor Box Furnaces With Reactor Boxes and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking Southwest at Reactor Box Furnaces With Reactor Boxes and Repossessed Uranium in Recycle Recovery Building - Hematite Fuel Fabrication Facility, Recycle Recovery Building, 3300 State Road P, Festus, Jefferson County, MO

  5. Development of a high-temperature durable catalyst for use in catalytic combustors for advanced automotive gas turbine engines

    NASA Astrophysics Data System (ADS)

    Tong, H.; Snow, G. C.; Chu, E. K.; Chang, R. L. S.; Angwin, M. J.; Pessagno, S. L.

    1981-09-01

    Durable catalytic reactors for advanced gas turbine engines were developed. Objectives were: to evaluate furnace aging as a cost effective catalytic reactor screening test, measure reactor degradation as a function of furnace aging, demonstrate 1,000 hours of combustion durability, and define a catalytic reactor system with a high probability of successful integration into an automotive gas turbine engine. Fourteen different catalytic reactor concepts were evaluated, leading to the selection of one for a durability combustion test with diesel fuel for combustion conditions. Eight additional catalytic reactors were evaluated and one of these was successfully combustion tested on propane fuel. This durability reactor used graded cell honeycombs and a combination of noble metal and metal oxide catalysts. The reactor was catalytically active and structurally sound at the end of the durability test.

  6. Moving bed reactor setup to study complex gas-solid reactions.

    PubMed

    Gupta, Puneet; Velazquez-Vargas, Luis G; Valentine, Charles; Fan, Liang-Shih

    2007-08-01

    A moving bed scale reactor setup for studying complex gas-solid reactions has been designed in order to obtain kinetic data for scale-up purpose. In this bench scale reactor setup, gas and solid reactants can be contacted in a cocurrent and countercurrent manner at high temperatures. Gas and solid sampling can be performed through the reactor bed with their composition profiles determined at steady state. The reactor setup can be used to evaluate and corroborate model parameters accounting for intrinsic reaction rates in both simple and complex gas-solid reaction systems. The moving bed design allows experimentation over a variety of gas and solid compositions in a single experiment unlike differential bed reactors where the gas composition is usually fixed. The data obtained from the reactor can also be used for direct scale-up of designs for moving bed reactors.

  7. Development of a high-temperature durable catalyst for use in catalytic combustors for advanced automotive gas turbine engines

    NASA Technical Reports Server (NTRS)

    Tong, H.; Snow, G. C.; Chu, E. K.; Chang, R. L. S.; Angwin, M. J.; Pessagno, S. L.

    1981-01-01

    Durable catalytic reactors for advanced gas turbine engines were developed. Objectives were: to evaluate furnace aging as a cost effective catalytic reactor screening test, measure reactor degradation as a function of furnace aging, demonstrate 1,000 hours of combustion durability, and define a catalytic reactor system with a high probability of successful integration into an automotive gas turbine engine. Fourteen different catalytic reactor concepts were evaluated, leading to the selection of one for a durability combustion test with diesel fuel for combustion conditions. Eight additional catalytic reactors were evaluated and one of these was successfully combustion tested on propane fuel. This durability reactor used graded cell honeycombs and a combination of noble metal and metal oxide catalysts. The reactor was catalytically active and structurally sound at the end of the durability test.

  8. Spinning fluids reactor

    DOEpatents

    Miller, Jan D; Hupka, Jan; Aranowski, Robert

    2012-11-20

    A spinning fluids reactor, includes a reactor body (24) having a circular cross-section and a fluid contactor screen (26) within the reactor body (24). The fluid contactor screen (26) having a plurality of apertures and a circular cross-section concentric with the reactor body (24) for a length thus forming an inner volume (28) bound by the fluid contactor screen (26) and an outer volume (30) bound by the reactor body (24) and the fluid contactor screen (26). A primary inlet (20) can be operatively connected to the reactor body (24) and can be configured to produce flow-through first spinning flow of a first fluid within the inner volume (28). A secondary inlet (22) can similarly be operatively connected to the reactor body (24) and can be configured to produce a second flow of a second fluid within the outer volume (30) which is optionally spinning.

  9. Plum Brook Reactor Facility Control Room during Facility Startup

    NASA Image and Video Library

    1961-02-21

    Operators test the National Aeronautics and Space Administration’s (NASA) Plum Brook Reactor Facility systems in the months leading up to its actual operation. The “Reactor On” signs are illuminated but the reactor core was not yet ready for chain reactions. Just a couple weeks after this photograph, Plum Brook Station held a media open house to unveil the 60-megawatt test reactor near Sandusky, Ohio. More than 60 members of the print media and radio and television news services met at the site to talk with community leaders and representatives from NASA and Atomic Energy Commission. The Plum Brook reactor went critical for the first time on the evening of June 14, 1961. It was not until April 1963 that the reactor reached its full potential of 60 megawatts. The reactor control room, located on the second floor of the facility, was run by licensed operators. The operators manually operated the shim rods which adjusted the chain reaction in the reactor core. The regulating rods could partially or completely shut down the reactor. The control room also housed remote area monitoring panels and other monitoring equipment that allowed operators to monitor radiation sensors located throughout the facility and to scram the reactor instantly if necessary. The color of the indicator lights corresponded with the elevation of the detectors in the various buildings. The reactor could also shut itself down automatically if the monitors detected any sudden irregularities.

  10. Research Program of a Super Fast Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oka, Yoshiaki; Ishiwatari, Yuki; Liu, Jie

    2006-07-01

    Research program of a supercritical-pressure light water cooled fast reactor (Super Fast Reactor) is funded by MEXT (Ministry of Education, Culture, Sports, Science and Technology) in December 2005 as one of the research programs of Japanese NERI (Nuclear Energy Research Initiative). It consists of three programs. (1) development of Super Fast Reactor concept; (2) thermal-hydraulic experiments; (3) material developments. The purpose of the concept development is to pursue the advantage of high power density of fast reactor over thermal reactors to achieve economic competitiveness of fast reactor for its deployment without waiting for exhausting uranium resources. Design goal is notmore » breeding, but maximizing reactor power by using plutonium from spent LWR fuel. MOX will be the fuel of the Super Fast Reactor. Thermal-hydraulic experiments will be conducted with HCFC22 (Hydro chlorofluorocarbons) heat transfer loop of Kyushu University and supercritical water loop at JAEA. Heat transfer data including effect of grid spacers will be taken. The critical flow and condensation of supercritical fluid will be studied. The materials research includes the development and testing of austenitic stainless steel cladding from the experience of PNC1520 for LMFBR. Material for thermal insulation will be tested. SCWR (Supercritical-Water Cooled Reactor) of GIF (Generation-4 International Forum) includes both thermal and fast reactors. The research of the Super Fast Reactor will enhance SCWR research and the data base. The research period will be until March 2010. (authors)« less

  11. Experiment for search for sterile neutrino at SM-3 reactor

    NASA Astrophysics Data System (ADS)

    Serebrov, A. P.; Ivochkin, V. G.; Samoylov, R. M.; Fomin, A. K.; Zinoviev, V. G.; Neustroev, P. V.; Golovtsov, V. L.; Gruzinsky, N. V.; Solovey, V. A.; Cherniy, A. V.; Zherebtsov, O. M.; Martemyanov, V. P.; Zinoev, V. G.; Tarasenkov, V. G.; Aleshin, V. I.; Petelin, A. L.; Pavlov, S. V.; Izhutov, A. L.; Sazontov, S. A.; Ryazanov, D. K.; Gromov, M. O.; Afanasiev, V. V.; Matrosov, L. N.; Matrosova, M. Yu.

    2016-11-01

    In connection with the question of possible existence of sterile neutrino the laboratory on the basis of SM-3 reactor was created to search for oscillations of reactor antineutrino. A prototype of a neutrino detector with scintillator volume of 400 l can be moved at the distance of 6-11 m from the reactor core. The measurements of background conditions have been made. It is shown that the main experimental problem is associated with cosmic radiation background. Test measurements of dependence of a reactor antineutrino flux on the distance from a reactor core have been made. The prospects of search for oscillations of reactor antineutrino at short distances are discussed.

  12. Zirconium Hydride Space Power Reactor design.

    NASA Technical Reports Server (NTRS)

    Asquith, J. G.; Mason, D. G.; Stamp, S.

    1972-01-01

    The Zirconium Hydride Space Power Reactor being designed and fabricated at Atomics International is intended for a wide range of potential applications. Throughout the program a series of reactor designs have been evaluated to establish the unique requirements imposed by coupling with various power conversion systems and for specific applications. Current design and development emphasis is upon a 100 kilowatt thermal reactor for application in a 5 kwe thermoelectric space power generating system, which is scheduled to be fabricated and ground tested in the mid 70s. The reactor design considerations reviewed in this paper will be discussed in the context of this 100 kwt reactor and a 300 kwt reactor previously designed for larger power demand applications.

  13. A document review to characterize Atomic International SNAP fuels shipped to INEL 1966--1973

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wahnschaffe, S.D.; Lords, R.E.; Kneff, D.W.

    1995-09-01

    This report provides the results of a document search and review study to obtain information on the spent fuels for the following six Nuclear Auxiliary Power (SNAP) reactor cores now stored at the Idaho National Engineering Laboratory (INEL): SNAP-2 Experimental Reactor, SNAP-2 Development Reactor, SNAP-10A Ground Test Reactor, SNAP-8 Experimental Reactor, SNAP-8 Development Reactor, and Shield Test Reactor. The report also covers documentation on SNAP fuel materials from four in-pile materials tests: NAA-82-1, NAA-115-2, NAA-117-1, and NAA-121. Pieces of these fuel materials are also stored at INEL as part of the SNAP fuel shipments.

  14. A Roadmap of Innovative Nuclear Energy System

    NASA Astrophysics Data System (ADS)

    Sekimoto, Hiroshi

    2017-01-01

    Nuclear is a dense energy without CO2 emission. It can be used for more than 100,000 years using fast breeder reactors with uranium from the sea. However, it raises difficult problems associated with severe accidents, spent fuel waste and nuclear threats, which should be solved with acceptable costs. Some innovative reactors have attracted interest, and many designs have been proposed for small reactors. These reactors are considered much safer than conventional large reactors and have fewer technical obstructions. Breed-and-burn reactors have high potential to solve all inherent problems for peaceful use of nuclear energy. However, they have some technical problems with materials. A roadmap for innovative reactors is presented herein.

  15. SNAP 10A FS-3 reactor performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hawley, J.P.; Johnson, R.A.

    1966-08-15

    SNAP 10FS-3 was the first flight-qualified SNAP reactor system to be operated in a simulated space environment. Prestart-up qualification testing, automatic start-up, endurance period performance, extended operation test and reactor shutdown are described as they affected, or were affected by, overall reactor performance. Performance of the reactor control system and the diagnostic instrumentation is critically evaluted.

  16. 10 CFR Appendix A to Part 110 - Illustrative List of Nuclear Reactor Equipment Under NRC Export Licensing Authority

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Illustrative List of Nuclear Reactor Equipment Under NRC... List of Nuclear Reactor Equipment Under NRC Export Licensing Authority Note—A nuclear reactor basically... nuclear reactor and capable of withstanding the operating pressure of the primary coolant. (2) On-line (e...

  17. 10 CFR Appendix A to Part 110 - Illustrative List of Nuclear Reactor Equipment Under NRC Export Licensing Authority

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Illustrative List of Nuclear Reactor Equipment Under NRC... List of Nuclear Reactor Equipment Under NRC Export Licensing Authority Note—A nuclear reactor basically... nuclear reactor and capable of withstanding the operating pressure of the primary coolant. (2) On-line (e...

  18. Method for passive cooling liquid metal cooled nuclear reactors, and system thereof

    DOEpatents

    Hunsbedt, Anstein; Busboom, Herbert J.

    1991-01-01

    A liquid metal cooled nuclear reactor having a passive cooling system for removing residual heat resulting from fuel decay during reactor shutdown. The passive cooling system comprises a plurality of partitions surrounding the reactor vessel in spaced apart relation forming intermediate areas for circulating heat transferring fluid which remove and carry away heat from the reactor vessel.

  19. 10 CFR 2.621 - Acceptance and docketing of application for early review of site suitability issues in a combined...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Director of the Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation, as...) The Director of the Office of New Reactors or the Director of the Office of Nuclear Reactor Regulation... of Nuclear Reactor Regulation, as appropriate, that they are complete. (c) If part one of the...

  20. High yields of hydrogen production from methanol steam reforming with a cross-U type reactor

    PubMed Central

    Zhang, Shubin; Chen, Junyu; Zhang, Xuelin; Liu, Xiaowei

    2017-01-01

    This paper presents a numerical and experimental study on the performance of a methanol steam reformer integrated with a hydrogen/air combustion reactor for hydrogen production. A CFD-based 3D model with mass and momentum transport and temperature characteristics is established. The simulation results show that better performance is achieved in the cross-U type reactor compared to either a tubular reactor or a parallel-U type reactor because of more effective heat transfer characteristics. Furthermore, Cu-based micro reformers of both cross-U and parallel-U type reactors are designed, fabricated and tested for experimental validation. Under the same condition for reforming and combustion, the results demonstrate that higher methanol conversion is achievable in cross-U type reactor. However, it is also found in cross-U type reactor that methanol reforming selectivity is the lowest due to the decreased water gas shift reaction under high temperature, thereby carbon monoxide concentration is increased. Furthermore, the reformed gas generated from the reactors is fed into a high temperature proton exchange membrane fuel cell (PEMFC). In the test of discharging for 4 h, the fuel cell fed by cross-U type reactor exhibits the most stable performance. PMID:29121067

  1. High yields of hydrogen production from methanol steam reforming with a cross-U type reactor.

    PubMed

    Zhang, Shubin; Zhang, Yufeng; Chen, Junyu; Zhang, Xuelin; Liu, Xiaowei

    2017-01-01

    This paper presents a numerical and experimental study on the performance of a methanol steam reformer integrated with a hydrogen/air combustion reactor for hydrogen production. A CFD-based 3D model with mass and momentum transport and temperature characteristics is established. The simulation results show that better performance is achieved in the cross-U type reactor compared to either a tubular reactor or a parallel-U type reactor because of more effective heat transfer characteristics. Furthermore, Cu-based micro reformers of both cross-U and parallel-U type reactors are designed, fabricated and tested for experimental validation. Under the same condition for reforming and combustion, the results demonstrate that higher methanol conversion is achievable in cross-U type reactor. However, it is also found in cross-U type reactor that methanol reforming selectivity is the lowest due to the decreased water gas shift reaction under high temperature, thereby carbon monoxide concentration is increased. Furthermore, the reformed gas generated from the reactors is fed into a high temperature proton exchange membrane fuel cell (PEMFC). In the test of discharging for 4 h, the fuel cell fed by cross-U type reactor exhibits the most stable performance.

  2. Pressurized fluidized bed reactor and a method of operating the same

    DOEpatents

    Isaksson, J.

    1996-02-20

    A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine. 1 fig.

  3. Pressurized fluidized bed reactor and a method of operating the same

    DOEpatents

    Isaksson, Juhani

    1996-01-01

    A pressurized fluid bed reactor power plant includes a fluidized bed reactor contained within a pressure vessel with a pressurized gas volume between the reactor and the vessel. A first conduit supplies primary gas from the gas volume to the reactor, passing outside the pressure vessel and then returning through the pressure vessel to the reactor, and pressurized gas is supplied from a compressor through a second conduit to the gas volume. A third conduit, comprising a hot gas discharge, carries gases from the reactor, through a filter, and ultimately to a turbine. During normal operation of the plant, pressurized gas is withdrawn from the gas volume through the first conduit and introduced into the reactor at a substantially continuously controlled rate as the primary gas to the reactor. In response to an operational disturbance of the plant, the flow of gas in the first, second, and third conduits is terminated, and thereafter the pressure in the gas volume and in the reactor is substantially simultaneously reduced by opening pressure relief valves in the first and third conduits, and optionally by passing air directly from the second conduit to the turbine.

  4. Operating characteristic analysis of a 400 mH class HTS DC reactor in connection with a laboratory scale LCC type HVDC system

    NASA Astrophysics Data System (ADS)

    Kim, Sung-Kyu; Kim, Kwangmin; Park, Minwon; Yu, In-Keun; Lee, Sangjin

    2015-11-01

    High temperature superconducting (HTS) devices are being developed due to their advantages. Most line commutated converter based high voltage direct current (HVDC) transmission systems for long-distance transmission require large inductance of DC reactor; however, generally, copper-based reactors cause a lot of electrical losses during the system operation. This is driving researchers to develop a new type of DC reactor using HTS wire. The authors have developed a 400 mH class HTS DC reactor and a laboratory scale test-bed for line-commutated converter type HVDC system and applied the HTS DC reactor to the HVDC system to investigate their operating characteristics. The 400 mH class HTS DC reactor is designed using a toroid type magnet. The HVDC system is designed in the form of a mono-pole system with thyristor-based 12-pulse power converters. In this paper, the investigation results of the HTS DC reactor in connection with the HVDC system are described. The operating characteristics of the HTS DC reactor are analyzed under various operating conditions of the system. Through the results, applicability of an HTS DC reactor in an HVDC system is discussed in detail.

  5. Potential of Electric Power Production from Microbial Fuel Cell (MFC) in Evapotranspiration Reactor for Leachate Treatment Using Alocasia macrorrhiza Plant and Eleusine indica Grass

    NASA Astrophysics Data System (ADS)

    Zaman, Badrus; Wardhana, Irawan Wisnu

    2018-02-01

    Microbial fuel cell is one of attractive electric power generator from nature bacterial activity. While, Evapotranspiration is one of the waste water treatment system which developed to eliminate biological weakness that utilize the natural evaporation process and bacterial activity on plant roots and plant media. This study aims to determine the potential of electrical energy from leachate treatment using evapotranspiration reactor. The study was conducted using local plant, namely Alocasia macrorrhiza and local grass, namely Eleusine Indica. The system was using horizontal MFC by placing the cathodes and anodes at different chamber (i.e. in the leachate reactor and reactor with plant media). Carbon plates was used for chatode-anodes material with size of 40 cm x 10 cm x1 cm. Electrical power production was measure by a digital multimeter for 30 days reactor operation. The result shows electric power production was fluctuated during reactor operation from all reactors. The electric power generated from each reactor was fluctuated, but from the reactor using Alocasia macrorrhiza plant reach to 70 μwatt average. From the reactor using Eleusine Indica grass was reached 60 μwatt average. Electric power production fluctuation is related to the bacterial growth pattern in the soil media and on the plant roots which undergo the adaptation process until the middle of the operational period and then in stable growth condition until the end of the reactor operation. The results indicate that the evapotranspiration reactor using Alocasia macrorrhiza plant was 60-95% higher electric power potential than using Eleusine Indica grass in short-term (30-day) operation. Although, MFC system in evapotranspiration reactor system was one of potential system for renewable electric power generation.

  6. Assessment of the Technical Maturity of Generation IV Concepts for Test or Demonstration Reactor Applications, Revision 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gougar, Hans David

    2015-10-01

    The United States Department of Energy (DOE) commissioned a study the suitability of different advanced reactor concepts to support materials irradiations (i.e. a test reactor) or to demonstrate an advanced power plant/fuel cycle concept (demonstration reactor). As part of the study, an assessment of the technical maturity of the individual concepts was undertaken to see which, if any, can support near-term deployment. A Working Group composed of the authors of this document performed the maturity assessment using the Technical Readiness Levels as defined in DOE’s Technology Readiness Guide . One representative design was selected for assessment from of each ofmore » the six Generation-IV reactor types: gas-cooled fast reactor (GFR), lead-cooled fast reactor (LFR), molten salt reactor (MSR), supercritical water-cooled reactor (SCWR), sodium-cooled fast reactor (SFR), and very high temperature reactor (VHTR). Background information was obtained from previous detailed evaluations such as the Generation-IV Roadmap but other technical references were also used including consultations with concept proponents and subject matter experts. Outside of Generation IV activity in which the US is a party, non-U.S. experience or data sources were generally not factored into the evaluations as one cannot assume that this data is easily available or of sufficient quality to be used for licensing a US facility. The Working Group established the scope of the assessment (which systems and subsystems needed to be considered), adapted a specific technology readiness scale, and scored each system through discussions designed to achieve internal consistency across concepts. In general, the Working Group sought to determine which of the reactor options have sufficient maturity to serve either the test or demonstration reactor missions.« less

  7. Preliminary study on aerobic granular biomass formation with aerobic continuous flow reactor

    NASA Astrophysics Data System (ADS)

    Yulianto, Andik; Soewondo, Prayatni; Handajani, Marissa; Ariesyady, Herto Dwi

    2017-03-01

    A paradigm shift in waste processing is done to obtain additional benefits from treated wastewater. By using the appropriate processing, wastewater can be turned into a resource. The use of aerobic granular biomass (AGB) can be used for such purposes, particularly for the processing of nutrients in wastewater. During this time, the use of AGB for processing nutrients more reactors based on a Sequencing Batch Reactor (SBR). Studies on the use of SBR Reactor for AGB demonstrate satisfactory performance in both formation and use. SBR reactor with AGB also has been applied on a full scale. However, the use use of SBR reactor still posses some problems, such as the need for additional buffer tank and the change of operation mode from conventional activated sludge to SBR. This gives room for further reactor research with the use of a different type, one of which is a continuous reactor. The purpose of this study is to compare AGB formation using continuous reactor and SBR with same operation parameter. Operation parameter are Organic Loading Rate (OLR) set to 2,5 Kg COD/m3.day with acetate as substrate, aeration rate 3 L/min, and microorganism from Hospital WWTP as microbial source. SBR use two column reactor with volumes 2 m3, and continuous reactor uses continuous airlift reactor, with two compartments and working volume of 5 L. Results from preliminary research shows that although the optimum results are not yet obtained, AGB can be formed on the continuous reactor. When compared with AGB generated by SBR, then the characteristics of granular diameter showed similarities, while the sedimentation rate and Sludge Volume Index (SVI) characteristics showed lower yields.

  8. Assessment of Sensor Technologies for Advanced Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Korsah, Kofi; Kisner, R. A.; Britton Jr., C. L.

    This paper provides an assessment of sensor technologies and a determination of measurement needs for advanced reactors (AdvRx). It is a summary of a study performed to provide the technical basis for identifying and prioritizing research targets within the instrumentation and control (I&C) Technology Area under the Department of Energy’s (DOE’s) Advanced Reactor Technology (ART) program. The study covered two broad reactor technology categories: High Temperature Reactors and Fast Reactors. The scope of “High temperature reactors” included Gen IV reactors whose coolant exit temperatures exceed ≈650 °C and are moderated (as opposed to fast reactors). To bound the scope formore » fast reactors, this report reviewed relevant operating experience from US-operated Sodium Fast Reactor (SFR) and relevant test experience from the Fast Flux Test Facility (FFTF). For high temperature reactors the study showed that in many cases instrumentation have performed reasonably well in research and demonstration reactors. However, even in cases where the technology is “mature” (such as thermocouples), HTGRs can benefit from improved technologies. Current HTGR instrumentation is generally based on decades-old technology and adapting newer technologies could provide significant advantages. For sodium fast reactors, the study found that several key research needs arise around (1) radiation-tolerant sensor design for in-vessel or in-core applications, where possible non-invasive sensing approaches for key parameters that minimize the need to deploy sensors in-vessel, (2) approaches to exfiltrating data from in-vessel sensors while minimizing penetrations, (3) calibration of sensors in-situ, and (4) optimizing sensor placements to maximize the information content while minimizing the number of sensors needed.« less

  9. Shutdown system for a nuclear reactor

    DOEpatents

    Groh, E.F.; Olson, A.P.; Wade, D.C.; Robinson, B.W.

    1984-06-05

    An ultimate shutdown system is provided for termination of neutronic activity in a nuclear reactor. The shutdown system includes bead chains comprising spherical containers suspended on a flexible cable. The containers are comprised of mating hemispherical shells which provide a ruggedized enclosure for reactor poison material. The bead chains, normally suspended above the reactor core on storage spools, are released for downward travel upon command from an external reactor monitor. The chains are capable of horizontal movement, so as to flow around obstructions in the reactor during their downward motion. 8 figs.

  10. Reactor vessel support system. [LMFBR

    DOEpatents

    Golden, M.P.; Holley, J.C.

    1980-05-09

    A reactor vessel support system includes a support ring at the reactor top supported through a box ring on a ledge of the reactor containment. The box ring includes an annular space in the center of its cross-section to reduce heat flow and is keyed to the support ledge to transmit seismic forces from the reactor vessel to the containment structure. A coolant channel is provided at the outside circumference of the support ring to supply coolant gas through the keyways to channels between the reactor vessel and support ledge into the containment space.

  11. NUCLEAR REACTOR AS THE OBJECT OF CONTROL. AUTOMATIC CONTROL OF AIRCRAFT ENGINES . B.S. Voronkev Collection of Articles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    BS> The dynamics of a power reactor is treated in some detail. Although the reactor is described by a nonlinear differential equation of the seventh order, a two-group approximstion with prompt neutrons and one averaged group of delayed neutrons may be used. When the reactor is in equilibrium, the reactor equation may be linearized in two ways. The effects of positive and negative coefficients of tins of the reactor are discussed. The nonlinear character of the control rods is trested. (D.L.C.)

  12. Shutdown system for a nuclear reactor

    DOEpatents

    Groh, Edward F.; Olson, Arne P.; Wade, David C.; Robinson, Bryan W.

    1984-01-01

    An ultimate shutdown system is provided for termination of neutronic activity in a nuclear reactor. The shutdown system includes bead chains comprising spherical containers suspended on a flexible cable. The containers are comprised of mating hemispherical shells which provide a ruggedized enclosure for reactor poison material. The bead chains, normally suspended above the reactor core on storage spools, are released for downward travel upon command from an external reactor monitor. The chains are capable of horizontal movement, so as to flow around obstructions in the reactor during their downward motion.

  13. Passive cooling safety system for liquid metal cooled nuclear reactors

    DOEpatents

    Hunsbedt, Anstein; Boardman, Charles E.; Hui, Marvin M.; Berglund, Robert C.

    1991-01-01

    A liquid metal cooled nuclear reactor having a passive cooling system for removing residual heat resulting from fuel decay during reactor shutdown. The passive cooling system comprises a plurality of partitions surrounding the reactor vessel in spaced apart relation forming intermediate areas for circulating heat transferring fluid which remove and carry away heat from the reactor vessel. The passive cooling system includes a closed primary fluid circuit through the partitions surrounding the reactor vessel and a partially adjoining secondary open fluid circuit for carrying transferred heat out into the atmosphere.

  14. Special features of the inverse-beta-decay reaction proceeding on a proton in a reactor-antineutrino flux

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kopeikin, V. I., E-mail: kopeikin46@yandex.ru; Skorokhvatov, M. D., E-mail: skorokhvatov-md@nrcki.ru

    2017-03-15

    The evolution of the reactor-antineutrino spectrum and the evolution of the spectrum of positrons from the inverse-beta-decay reaction in the course of reactor operation and after reactor shutdown are considered. The present-day status in determining the initial reactor-antineutrino spectrum on the basis of spectra of beta particles from mixtures of products originating from uranium and plutonium fission is described. A local rise of the experimental spectrum of reactor antineutrinos with respect to the expected spectrum is studied.

  15. An atmospheric pressure flow reactor: Gas phase kinetics and mechanism in tropospheric conditions without wall effects

    NASA Technical Reports Server (NTRS)

    Koontz, Steven L.; Davis, Dennis D.; Hansen, Merrill

    1988-01-01

    A new type of gas phase flow reactor, designed to permit the study of gas phase reactions near 1 atm of pressure, is described. A general solution to the flow/diffusion/reaction equations describing reactor performance under pseudo-first-order kinetic conditions is presented along with a discussion of critical reactor parameters and reactor limitations. The results of numerical simulations of the reactions of ozone with monomethylhydrazine and hydrazine are discussed, and performance data from a prototype flow reactor are presented.

  16. DOE/NNSA perspective safeguard by design: GEN III/III+ light water reactors and beyond

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pan, Paul Y

    2010-12-10

    An overview of key issues relevant to safeguards by design (SBD) for GEN III/IV nuclear reactors is provided. Lessons learned from construction of typical GEN III+ water reactors with respect to SBD are highlighted. Details of SBD for safeguards guidance development for GEN III/III+ light water reactors are developed and reported. This paper also identifies technical challenges to extend SBD including proliferation resistance methodologies to other GEN III/III+ reactors (except HWRs) and GEN IV reactors because of their immaturity in designs.

  17. Nuclear engine flow reactivity shim control

    DOEpatents

    Walsh, J.M.

    1973-12-11

    A nuclear engine control system is provided which automatically compensates for reactor reactivity uncertainties at the start of life and reactivity losses due to core corrosion during the reactor life in gas-cooled reactors. The coolant gas flow is varied automatically by means of specially provided control apparatus so that the reactor control drums maintain a predetermined steady state position throughout the reactor life. This permits the reactor to be designed for a constant drum position and results in a desirable, relatively flat temperature profile across the core. (Official Gazette)

  18. Nuclear Thermal Propulsion: A Joint NASA/DOE/DOD Workshop

    NASA Technical Reports Server (NTRS)

    Clark, John S. (Editor)

    1991-01-01

    Papers presented at the joint NASA/DOE/DOD workshop on nuclear thermal propulsion are compiled. The following subject areas are covered: nuclear thermal propulsion programs; Rover/NERVA and NERVA systems; Low Pressure Nuclear Thermal Rocket (LPNTR); particle bed reactor nuclear rocket; hybrid propulsion systems; wire core reactor; pellet bed reactor; foil reactor; Droplet Core Nuclear Rocket (DCNR); open cycle gas core nuclear rockets; vapor core propulsion reactors; nuclear light bulb; Nuclear rocket using Indigenous Martian Fuel (NIMF); mission analysis; propulsion and reactor technology; development plans; and safety issues.

  19. Control rod drive for reactor shutdown

    DOEpatents

    McKeehan, Ernest R.; Shawver, Bruce M.; Schiro, Donald J.; Taft, William E.

    1976-01-20

    A means for rapidly shutting down or scramming a nuclear reactor, such as a liquid metal-cooled fast breeder reactor, and serves as a backup to the primary shutdown system. The control rod drive consists basically of an in-core assembly, a drive shaft and seal assembly, and a control drive mechanism. The control rod is driven into the core region of the reactor by gravity and hydraulic pressure forces supplied by the reactor coolant, thus assuring that common mode failures will not interfere with or prohibit scramming the reactor when necessary.

  20. Indirect passive cooling system for liquid metal cooled nuclear reactors

    DOEpatents

    Hunsbedt, Anstein; Boardman, Charles E.

    1990-01-01

    A liquid metal cooled nuclear reactor having a passive cooling system for removing residual heat resulting from fuel decay during reactor shutdown. The passive cooling system comprises a plurality of partitions surrounding the reactor vessel in spaced apart relation forming intermediate areas for circulating heat transferring fluid which remove and carry away heat from the reactor vessel. The passive cooling system includes a closed primary fluid circuit through the partitions surrounding the reactor vessel and a partially adjoining secondary open fluid circuit for carrying transferred heat out into the atmosphere.

  1. Self isolating high frequency saturable reactor

    DOEpatents

    Moore, James A.

    1998-06-23

    The present invention discloses a saturable reactor and a method for decoupling the interwinding capacitance from the frequency limitations of the reactor so that the equivalent electrical circuit of the saturable reactor comprises a variable inductor. The saturable reactor comprises a plurality of physically symmetrical magnetic cores with closed loop magnetic paths and a novel method of wiring a control winding and a RF winding. The present invention additionally discloses a matching network and method for matching the impedances of a RF generator to a load. The matching network comprises a matching transformer and a saturable reactor.

  2. Thorium fueled reactor

    NASA Astrophysics Data System (ADS)

    Sipaun, S.

    2017-01-01

    Current development in thorium fueled reactors shows that they can be designed to operate in the fast or thermal spectrum. The thorium/uranium fuel cycle converts fertile thorium-232 into fissile uranium-233, which fissions and releases energy. This paper analyses the characteristics of thorium fueled reactors and discusses the thermal reactor option. It is found that thorium fuel can be utilized in molten salt reactors through many configurations and designs. A balanced assessment on the feasibility of adopting one reactor technology versus another could lead to optimized benefits of having thorium resource.

  3. A Basic LEGO Reactor Design for the Provision of Lunar Surface Power

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    John Darrell Bess

    2008-06-01

    A final design has been established for a basic Lunar Evolutionary Growth-Optimized (LEGO) Reactor using current and near-term technologies. The LEGO Reactor is a modular, fast-fission, heatpipe-cooled, clustered-reactor system for lunar-surface power generation. The reactor is divided into subcritical units that can be safely launched with lunar shipments from Earth, and then emplaced directly into holes drilled into the lunar regolith to form a critical reactor assembly. The regolith would not just provide radiation shielding, but serve as neutron-reflector material as well. The reactor subunits are to be manufactured using proven and tested materials for use in radiation environments, suchmore » as uranium-dioxide fuel, stainless-steel cladding and structural support, and liquid-sodium heatpipes. The LEGO Reactor system promotes reliability, safety, and ease of manufacture and testing at the cost of an increase in launch mass per overall rated power level and a reduction in neutron economy when compared to a single-reactor system. A single unshielded LEGO Reactor subunit has an estimated mass of approximately 448 kg and provides approximately 5 kWe. The overall envelope for a single subunit with fully extended radiator panels has a height of 8.77 m and a diameter of 0.50 m. Six subunits could provide sufficient power generation throughout the initial stages of establishing a lunar outpost. Portions of the reactor may be neutronically decoupled to allow for reduced power production during unmanned periods of base operations. During later stages of lunar-base development, additional subunits may be emplaced and coupled into the existing LEGO Reactor network, subject to lunar base power demand. Improvements in reactor control methods, fuel form and matrix, shielding, as well as power conversion and heat rejection techniques can help generate an even more competitive LEGO Reactor design. Further modifications in the design could provide power generative opportunities for use on other extraterrestrial surfaces.« less

  4. Small space reactor power systems for unmanned solar system exploration missions

    NASA Technical Reports Server (NTRS)

    Bloomfield, Harvey S.

    1987-01-01

    A preliminary feasibility study of the application of small nuclear reactor space power systems to the Mariner Mark II Cassini spacecraft/mission was conducted. The purpose of the study was to identify and assess the technology and performance issues associated with the reactor power system/spacecraft/mission integration. The Cassini mission was selected because study of the Saturn system was identified as a high priority outer planet exploration objective. Reactor power systems applied to this mission were evaluated for two different uses. First, a very small 1 kWe reactor power system was used as an RTG replacement for the nominal spacecraft mission science payload power requirements while still retaining the spacecraft's usual bipropellant chemical propulsion system. The second use of reactor power involved the additional replacement of the chemical propulsion system with a small reactor power system and an electric propulsion system. The study also provides an examination of potential applications for the additional power available for scientific data collection. The reactor power system characteristics utilized in the study were based on a parametric mass model that was developed specifically for these low power applications. The model was generated following a neutronic safety and operational feasibility assessment of six small reactor concepts solicited from U.S. industry. This assessment provided the validation of reactor safety for all mission phases and generatad the reactor mass and dimensional data needed for the system mass model.

  5. A brief history of design studies on innovative nuclear reactors

    NASA Astrophysics Data System (ADS)

    Sekimoto, Hiroshi

    2014-09-01

    In a short period after the success of CP1, many types of nuclear reactors were proposed and investigated. However, soon only a small number of reactors were selected for practical use. Around 1970, only LWRs with small number of CANDUs were operated in the western world, and FBRs were under development. It was about the time when Apollo moon landing was accomplished. However, at the same time, the future of human being was widely considered pessimistic and Limits to Growth was published. In the end of 1970's the TMI accident occurred and many nuclear reactor contracts were cancelled in USA and any more contracts had not been concluded until recent years. From the reflection of this accident, many Inherent Safe Reactors (ISRs) were proposed, though none of them were constructed. A common idea of ISRs is smallness of their size. Tokyo Institute of Technology (TokyoTech) held a symposium on small reactors, SR/TIT, in 1991, where many types of small ISRs were presented. Recently small reactors attract interest again. The most ideas employed in these reactors were the same discussed in SR/TIT. In 1980's the radioactive wastes from fuel cycle became a severe problem around the world. In TokyoTech, this issue was discussed mainly from the viewpoint of nuclear transmutations. The neutron economy became inevitable for these innovative nuclear reactors especially small long-life reactors and transmutation reactors.

  6. WORKER STACKS GRAPHITE BLOCKS AGAINST INNER SOUTH WALL OF REACTOR. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    WORKER STACKS GRAPHITE BLOCKS AGAINST INNER SOUTH WALL OF REACTOR. INL NEGATIVE NO. 3925. Unknown Photographer, 12/14/1951 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  7. Looking Northeast in Oxide Building at Reactors on Second Floor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking Northeast in Oxide Building at Reactors on Second Floor Including Reactor One (Left) and Reactor Two (Right) - Hematite Fuel Fabrication Facility, Oxide Building & Oxide Loading Dock, 3300 State Road P, Festus, Jefferson County, MO

  8. Preliminary Comparison of Radioactive Waste Disposal Cost for Fusion and Fission Reactors

    NASA Astrophysics Data System (ADS)

    Seki, Yasushi; Aoki, Isao; Yamano, Naoki; Tabara, Takashi

    1997-09-01

    The environmental and economic impact of radioactive waste (radwaste) generated from fusion power reactors using five types of structural materials and a fission reactor has been evaluated and compared. Possible radwaste disposal scenario of fusion radwaste in Japan is considered. The exposure doses were evaluated for the skyshine of gamma-ray during the disposal operation, groundwater migration scenario during the institutional control period of 300 years and future site use scenario after the institutional period. The radwaste generated from a typical light water fission reactor was evaluated using the same methodology as for the fusion reactors. It is found that radwaste from the fusion reactors using F82H and SiC/SiC composites without impurities could be disposed by the shallow land disposal presently applied to the low level waste in Japan. The disposal cost of radwaste from five fusion power reactors and a typical light water reactor were roughly evaluated and compared.

  9. High throughput semiconductor deposition system

    DOEpatents

    Young, David L.; Ptak, Aaron Joseph; Kuech, Thomas F.; Schulte, Kevin; Simon, John D.

    2017-11-21

    A reactor for growing or depositing semiconductor films or devices. The reactor may be designed for inline production of III-V materials grown by hydride vapor phase epitaxy (HVPE). The operating principles of the HVPE reactor can be used to provide a completely or partially inline reactor for many different materials. An exemplary design of the reactor is shown in the attached drawings. In some instances, all or many of the pieces of the reactor formed of quartz, such as welded quartz tubing, while other reactors are made from metal with appropriate corrosion resistant coatings such as quartz or other materials, e.g., corrosion resistant material, or stainless steel tubing or pipes may be used with a corrosion resistant material useful with HVPE-type reactants and gases. Using HVPE in the reactor allows use of lower-cost precursors at higher deposition rates such as in the range of 1 to 5 .mu.m/minute.

  10. Nuclear reactor vessel fuel thermal insulating barrier

    DOEpatents

    Keegan, C. Patrick; Scobel, James H.; Wright, Richard F.

    2013-03-19

    The reactor vessel of a nuclear reactor installation which is suspended from the cold leg nozzles in a reactor cavity is provided with a lower thermal insulating barrier spaced from the reactor vessel that has a hemispherical lower section that increases in volume from the center line of the reactor to the outer extent of the diameter of the thermal insulating barrier and smoothly transitions up the side walls of the vessel. The space between the thermal insulating harrier and the reactor vessel forms a chamber which can be flooded with cooling water through passive valving to directly cool the reactor vessel in the event of a severe accident. The passive inlet valve for the cooling water includes a buoyant door that is normally maintained sealed under its own weight and floats open when the cavity is Hooded. Passively opening steam vents are also provided.

  11. Nuclear reactors built, being built, or planned, 1991

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simpson, B.

    1992-07-01

    This document contains unclassified information about facilities built, being built, or planned in the United States for domestic use or export as of December 31, 1991. The book is divided into three major sections: Section 1 consists of a reactor locator map and reactor tables; Section 2 includes nuclear reactors that are operating, being built, or planned; and Section 3 includes reactors that have been shut down permanently or dismantled. Sections 2 and 3 contain the following classification of reactors: Civilian, Production, Military, Export, and Critical Assembly. Export reactor refers to a reactor for which the principal nuclear contractor ismore » an American company -- working either independently or in cooperation with a foreign company (Part 4, in each section). Critical assembly refers to an assembly of fuel and assembly of fuel and moderator that requires an external source of neutrons to initiate and maintain fission. A critical assembly is used for experimental measurements (Part 5).« less

  12. Nuclear component horizontal seismic restraint

    DOEpatents

    Snyder, Glenn J.

    1988-01-01

    A nuclear component horizontal seismic restraint. Small gaps limit horizontal displacement of components during a seismic occurrence and therefore reduce dynamic loadings on the free lower end. The reactor vessel and reactor guard vessel use thicker section roll-forged rings welded between the vessel straight shell sections and the bottom hemispherical head sections. The inside of the reactor guard vessel ring forging contains local vertical dovetail slots and upper ledge pockets to mount and retain field fitted and installed blocks. As an option, the horizontal displacement of the reactor vessel core support cone can be limited by including shop fitted/installed local blocks in opposing alignment with the reactor vessel forged ring. Beams embedded in the wall of the reactor building protrude into apertures in the thermal insulation shell adjacent the reactor guard vessel ring and have motion limit blocks attached thereto to provide to a predetermined clearance between the blocks and reactor guard vessel ring.

  13. Safety control circuit for a neutronic reactor

    DOEpatents

    Ellsworth, Howard C.

    2004-04-27

    A neutronic reactor comprising an active portion containing material fissionable by neutrons of thermal energy, means to control a neutronic chain reaction within the reactor comprising a safety device and a regulating device, a safety device including means defining a vertical channel extending into the reactor from an aperture in the upper surface of the reactor, a rod containing neutron-absorbing materials slidably disposed within the channel, means for maintaining the safety rod in a withdrawn position relative to the active portion of the reactor including means for releasing said rod on actuation thereof, a hopper mounted above the active portion of the reactor having a door disposed at the bottom of the hopper opening into the vertical channel, a plurality of bodies of neutron-absorbing materials disposed within the hopper, and means responsive to the failure of the safety rod on actuation thereof to enter the active portion of the reactor for opening the door in the hopper.

  14. Eastern Europe Research Reactor Initiative nuclear education and training courses - Current activities and future challenges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Snoj, L.; Sklenka, L.; Rataj, J.

    2012-07-01

    The Eastern Europe Research Reactor Initiative was established in January 2008 to enhance cooperation between the Research Reactors in Eastern Europe. It covers three areas of research reactor utilisation: irradiation of materials and fuel, radioisotope production, neutron beam experiments, education and training. In the field of education and training an EERRI training course was developed. The training programme has been elaborated with the purpose to assist IAEA Member States, which consider building a research reactor (RR) as a first step to develop nuclear competence and infrastructure in the Country. The major strength of the reactor is utilisation of three differentmore » research reactors and a lot of practical exercises. Due to high level of adaptability, the course can be tailored to specific needs of institutions with limited or no access to research reactors. (authors)« less

  15. Eddy Current Flow Measurements in the FFTF

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nielsen, Deborah L.; Polzin, David L.; Omberg, Ronald P.

    2017-02-02

    The Fast Flux Test Facility (FFTF) is the most recent liquid metal reactor (LMR) to be designed, constructed, and operated by the U.S. Department of Energy (DOE). The 400-MWt sodium-cooled, fast-neutron flux reactor plant was designed for irradiation testing of nuclear reactor fuels and materials for liquid metal fast breeder reactors. Following shut down of the Clinch River Breeder Reactor Plant (CRBRP) project in 1983, FFTF continued to play a key role in providing a test bed for demonstrating performance of advanced fuel designs and demonstrating operation, maintenance, and safety of advanced liquid metal reactors. The FFTF Program provides valuablemore » information for potential follow-on reactor projects in the areas of plant system and component design, component fabrication, fuel design and performance, prototype testing, site construction, and reactor control and operations. This report provides HEDL-TC-1344, “ECFM Flow Measurements in the FFTF Using Phase-Sensitive Detectors”, March 1979.« less

  16. Transmutation of actinides in power reactors.

    PubMed

    Bergelson, B R; Gerasimov, A S; Tikhomirov, G V

    2005-01-01

    Power reactors can be used for partial short-term transmutation of radwaste. This transmutation is beneficial in terms of subsequent storage conditions for spent fuel in long-term storage facilities. CANDU-type reactors can transmute the main minor actinides from two or three reactors of the VVER-1000 type. A VVER-1000-type reactor can operate in a self-service mode with transmutation of its own actinides.

  17. Double-clad nuclear fuel safety rod

    DOEpatents

    McCarthy, William H.; Atcheson, Donald B.; Vaidyanathan, Swaminathan

    1984-01-01

    A device for shutting down a nuclear reactor during an undercooling or overpower event, whether or not the reactor's scram system operates properly. This is accomplished by double-clad fuel safety rods positioned at various locations throughout the reactor core, wherein melting of a secondary internal cladding of the rod allows the fuel column therein to shift from the reactor core to place the reactor in a subcritical condition.

  18. Double-clad nuclear-fuel safety rod

    DOEpatents

    McCarthy, W.H.; Atcheson, D.B.

    1981-12-30

    A device for shutting down a nuclear reactor during an undercooling or overpower event, whether or not the reactor's scram system operates properly. This is accomplished by double-clad fuel safety rods positioned at various locations throughout the reactor core, wherein melting of a secondary internal cladding of the rod allows the fuel column therein to shift from the reactor core to place the reactor in a subcritical condition.

  19. NEUTRONIC REACTOR POWER PLANT

    DOEpatents

    Metcalf, H.E.

    1962-12-25

    This patent relates to a nuclear reactor power plant incorporating an air-cooled, beryllium oxide-moderated, pebble bed reactor. According to the invention means are provided for circulating a flow of air through tubes in the reactor to a turbine and for directing a sidestream of the circu1ating air through the pebble bed to remove fission products therefrom as well as assist in cooling the reactor. (AEC)

  20. U.S. Nuclear Cooperation with India: Issues for Congress

    DTIC Science & Technology

    2008-11-03

    separation list: ! 8 indigenous Indian power reactors ! Fast Breeder test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction...facilities like reprocessing and enrichment plants and breeder reactors could be viewed as providing a significant nonproliferation benefit because the... breeder reactors would support the 2002 U.S. National Strategy to Combat Weapons of Mass Destruction, in which the United States pledged to “continue to

  1. U.S. Nuclear Cooperation with India: Issues for Congress

    DTIC Science & Technology

    2008-10-02

    8 indigenous Indian power reactors ! Fast Breeder test Reactor (FTBR) and Prototype Fast Breeder Reactors (PFBR) under construction ! Enrichment... breeder reactors could be viewed as providing a significant nonproliferation benefit because the materials produced by these plants are a few steps closer...to potential use in a bomb. In addition, safeguards on enrichment, reprocessing plants, and breeder reactors would support the 2002 U.S. National

  2. BUILDING FOR THE EXPERIMENTAL SWIMMING POOL REACTOR OF 3Mw OF THE JUNTA DE ENERGIA NUCLEAR (in Spanish)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    de la Camara, S.N.

    1958-10-01

    The Spanish experimental swimming pool reactor is constructed on the grounds of the Ciudad Universitaria de Madrid. A general layout of the reactor building and its annexes is given, and the reactor building itself is described. The construction of the reactor building and the characteristics of the annex building are discussed. (J.S.R.)

  3. PRELIMINARY HAZARDS SUMMARY REPORT FOR THE VALLECITOS SUPERHEAT REACTOR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murray, J.L.

    1961-02-01

    BS>The Vallecitos Superheat Reactor (VSR) is a light-watermoderated, thermal-spectrum reactor, cooled by a combination of moderator boiling and forced convection cooling with saturated steam. The reactor core consists of 32 fuel hurdles containing 5300 lb of UO/sub 2/ enriched in U/sub 235/ to 3.6%. The fuel elements are arranged in individual process tubes that direct the cooling steam flow and separate the steam from the water moderator. The reactor vessel is designed for 1250 psig and operates at 960 to 1000 psig. With the reactor operating at 12.5 Mw(t), the maximum fuel cladding temperature is 1250 deg F and themore » cooling steam is superheated to an average temperature of about 810 deg F at 905 psig. Nu clear operation of the reactor is controlled by 12 control rods, actuated by drives mounted on the bottom of the reactor vessel. The water moderator recirculates inside the reactor vessel and through the core region by natural convection. Inherent safety features of the reactor include the negative core reactivity effects upon heating the UO/sub 2/ fuel (Doppler effect), upon increasing the temperature or void content of the moderator in the operating condition, and upon unflooding the fuel process tubes in the hot condition. Snfety features designed into the reactor and plant systems include a system of sensors and devices to detect petentially unsafe operating conditions and to initiate automatically the appropriate countermeasures, a set of fast and reliable control rods for scramming the reactor if a potentially unsafe condition occurs, a manually-actuated liquid neutron poison system, and an emergency cooling system to provide continued steam flow through the reactor core in the event the reactor becomes isolated from either its normal source of steam supply or discharge. The release of radioactivity to unrestricted areas is maintained within permissible limits by monitoring the radioactivity of wastes and controlling their release. The reactor and many of its auxiliaries are housed within a high-integrity essentially leak-tight containment vessel. (auth)« less

  4. Fast formation of aerobic granules by combining strong hydraulic selection pressure with overstressed organic loading rate.

    PubMed

    Liu, Yong-Qiang; Tay, Joo-Hwa

    2015-09-01

    The combined strong hydraulic selection pressure (HSP) with overstressed organic loading rate (OLR) as a fast granulation strategy was used to enhance aerobic granulation. To investigate the wide applicability of this strategy to different scenarios and its relevant mechanism, different settling times, different inoculums, different exchange ratios, different reactor configurations, and different shear force were used in this study. It was found that clear granules were formed within 24 h and steady state reached within three days when the fast granulation strategy was used in a lab-scale reactor seeded with well settled activated sludge (Reactor 2). However, granules appeared after 2-week operation and reached steady state after one month at the traditional step-wise decreased settling time from 20 to 2 min with OLR of 6 g COD/L·d (Reactor 1). With the fast granulation strategy, granules appeared within 24 h even with bulking sludge as seed to start up Reactor 3, but 6-day lag phase was observed compared with Reactor 2. Both Reactor 2 and Reactor 3 experienced sigmoidal growth curve in terms of biomass accumulation and granule size increase after granulation. In addition, the reproducible results in pilot-scale reactors (Reactor 5 and Reactor 6) with diameter of 20 cm and height/diameter ratio (H/D) of 4 further proved that reactor configuration and fluid flow pattern had no effect on the aerobic granulation when the fast granulation strategy was employed, but biomass accumulation experienced a short lag phase too in Reactor 5 and Reactor 6. Although overstressed OLR was favorable for fast granulation, it also led to the fluffy granules after around two-week operation. However, the stable 6-month operation of Reactor 3 demonstrated that the rapidly formed granules were able to maintain long-term stability by reducing OLR from 12 g COD/L·d to 6 g COD/L·d. A mechanism of fast granulation with the strategy of combined strong HSP and OLR was proposed to explain results and guide the operation with this fast strategy. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Application of ATHLET/DYN3D coupled codes system for fast liquid metal cooled reactor steady state simulation

    NASA Astrophysics Data System (ADS)

    Ivanov, V.; Samokhin, A.; Danicheva, I.; Khrennikov, N.; Bouscuet, J.; Velkov, K.; Pasichnyk, I.

    2017-01-01

    In this paper the approaches used for developing of the BN-800 reactor test model and for validation of coupled neutron-physic and thermohydraulic calculations are described. Coupled codes ATHLET 3.0 (code for thermohydraulic calculations of reactor transients) and DYN3D (3-dimensional code of neutron kinetics) are used for calculations. The main calculation results of reactor steady state condition are provided. 3-D model used for neutron calculations was developed for start reactor BN-800 load. The homogeneous approach is used for description of reactor assemblies. Along with main simplifications, the main reactor BN-800 core zones are described (LEZ, MEZ, HEZ, MOX, blankets). The 3D neutron physics calculations were provided with 28-group library, which is based on estimated nuclear data ENDF/B-7.0. Neutron SCALE code was used for preparation of group constants. Nodalization hydraulic model has boundary conditions by coolant mass-flow rate for core inlet part, by pressure and enthalpy for core outlet part, which can be chosen depending on reactor state. Core inlet and outlet temperatures were chosen according to reactor nominal state. The coolant mass flow rate profiling through the core is based on reactor power distribution. The test thermohydraulic calculations made with using of developed model showed acceptable results in coolant mass flow rate distribution through the reactor core and in axial temperature and pressure distribution. The developed model will be upgraded in future for different transient analysis in metal-cooled fast reactors of BN type including reactivity transients (control rods withdrawal, stop of the main circulation pump, etc.).

  6. How to Produce a Reactor Neutron Spectrum Using a Proton Accelerator

    DOE PAGES

    Burns, Kimberly A.; Wootan, David W.; Gates, Robert O.; ...

    2015-06-18

    A method for reproducing the neutron energy spectrum present in the core of an operating nuclear reactor using an engineered target in an accelerator proton beam is proposed. The protons interact with a target to create neutrons through various (p,n) type reactions. Spectral tailoring of the emitted neutrons can be used to modify the energy of the generated neutron spectrum to represent various reactor spectra. Through the use of moderators and reflectors, the neutron spectrum can be modified to reproduce many different spectra of interest including spectra in small thermal test reactors, large pressurized water reactors, and fast reactors. Themore » particular application of this methodology is the design of an experimental approach for using an accelerator to measure the betas produced during fission to be used to reduce uncertainties in the interpretation of reactor antineutrino measurements. This approach involves using a proton accelerator to produce a neutron field representative of a power reactor, and using this neutron field to irradiate fission foils of the primary isotopes contributing to fission in the reactor, creating unstable, neutron rich fission products that subsequently beta decay and emit electron antineutrinos. A major advantage of an accelerator neutron source over a neutron beam from a thermal reactor is that the fast neutrons can be slowed down or tailored to approximate various power reactor spectra. An accelerator based neutron source that can be tailored to match various reactor neutron spectra provides an advantage for control in studying how changes in the neutron spectra affect parameters such as the resulting fission product beta spectrum.« less

  7. Biological hydrogen production by Clostridium acetobutylicum in an unsaturated flow reactor.

    PubMed

    Zhang, Husen; Bruns, Mary Ann; Logan, Bruce E

    2006-02-01

    A mesophilic unsaturated flow (trickle bed) reactor was designed and tested for H2 production via fermentation of glucose. The reactor consisted of a column packed with glass beads and inoculated with a pure culture (Clostridium acetobutylicum ATCC 824). A defined medium containing glucose was fed at a flow rate of 1.6 mL/min (0.096 L/h) into the capped reactor, producing a hydraulic retention time of 2.1 min. Gas-phase H2 concentrations were constant, averaging 74 +/- 3% for all conditions tested. H2 production rates increased from 89 to 220 mL/hL of reactor when influent glucose concentrations were varied from 1.0 to 10.5 g/L. Specific H2 production rate ranged from 680 to 1270 mL/g glucose per liter of reactor (total volume). The H2 yield was 15-27%, based on a theoretical limit by fermentation of 4 moles of H2 from 1 mole of glucose. The major fermentation by-products in the liquid effluent were acetate and butyrate. The reactor rapidly (within 60-72 h) became clogged with biomass, requiring manual cleaning of the system. In order to make long-term operation of the reactor feasible, biofilm accumulation in the reactor will need to be controlled through some process such as backwashing. These tests using an unsaturated flow reactor demonstrate the feasibility of the process to produce high H2 gas concentrations in a trickle-bed type of reactor. A likely application of this reactor technology could be H2 gas recovery from pre-treatment of high carbohydrate-containing wastewaters.

  8. Fail-safe reactivity compensation method for a nuclear reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nygaard, Erik T.; Angelo, Peter L.; Aase, Scott B.

    The present invention relates generally to the field of compensation methods for nuclear reactors and, in particular to a method for fail-safe reactivity compensation in solution-type nuclear reactors. In one embodiment, the fail-safe reactivity compensation method of the present invention augments other control methods for a nuclear reactor. In still another embodiment, the fail-safe reactivity compensation method of the present invention permits one to control a nuclear reaction in a nuclear reactor through a method that does not rely on moving components into or out of a reactor core, nor does the method of the present invention rely on themore » constant repositioning of control rods within a nuclear reactor in order to maintain a critical state.« less

  9. HORIZONTAL BOILING REACTOR SYSTEM

    DOEpatents

    Treshow, M.

    1958-11-18

    Reactors of the boiling water type are described wherein water serves both as the moderator and coolant. The reactor system consists essentially of a horizontal pressure vessel divided into two compartments by a weir, a thermal neutronic reactor core having vertical coolant passages and designed to use water as a moderator-coolant posltioned in one compartment, means for removing live steam from the other compartment and means for conveying feed-water and water from the steam compartment to the reactor compartment. The system further includes auxiliary apparatus to utilize the steam for driving a turbine and returning the condensate to the feed-water inlet of the reactor. The entire system is designed so that the reactor is self-regulating and has self-limiting power and self-limiting pressure features.

  10. Low-power lead-cooled fast reactor loaded with MOX-fuel

    NASA Astrophysics Data System (ADS)

    Sitdikov, E. R.; Terekhova, A. M.

    2017-01-01

    Fast reactor for the purpose of implementation of research, education of undergraduate and doctoral students in handling innovative fast reactors and training specialists for atomic research centers and nuclear power plants (BRUTs) was considered. Hard neutron spectrum achieved in the fast reactor with compact core and lead coolant. Possibility of prompt neutron runaway of the reactor is excluded due to the low reactivity margin which is less than the effective fraction of delayed neutrons. The possibility of using MOX fuel in the BRUTs reactor was examined. The effect of Keff growth connected with replacement of natural lead coolant to 208Pb coolant was evaluated. The calculations and reactor core model were performed using the Serpent Monte Carlo code.

  11. Extension of the TRANSURANUS burnup model to heavy water reactor conditions

    NASA Astrophysics Data System (ADS)

    Lassmann, K.; Walker, C. T.; van de Laar, J.

    1998-06-01

    The extension of the light water reactor burnup equations of the TRANSURANUS code to heavy water reactor conditions is described. Existing models for the fission of 235U and the buildup of plutonium in a heavy water reactor are evaluated. In order to overcome the limitations of the frequently used RADAR model at high burnup, a new model is presented. After verification against data for the radial distributions of Xe, Cs, Nd and Pu from electron probe microanalysis, the model is used to analyse the formation of the high burnup structure in a heavy water reactor. The new model allows the analysis of light water reactor fuel rod designs at high burnup in the OECD Halden Heavy Water Reactor.

  12. METHOD FOR SENSING DEGREE OF FLUIDIZATION IN FLUIDIZED BED

    DOEpatents

    Levey, R.P. Jr.; Fowler, A.H.

    1961-12-12

    A method is given for detecting, indicating, and controlling the degree of fluidization in a fluid-bed reactor into which powdered material is fed. The method comprises admitting of gas into the reactor, inserting a springsupported rod into the powder bed of the reactor, exciting the rod to vibrate at its resonant frequency, deriving a signal responsive to the amplitude of vibi-ation of the rod and spring, the signal being directiy proportional to the rate of flow of the gas through the reactor, displaying the signal to provide an indication of the degree of fluidization within the reactor, and controlling the rate of gas flow into the reactor until said signal stabilizes at a constant value to provide substantially complete fluidization within the reactor. (AEC)

  13. Fuel Cycle Performance of Thermal Spectrum Small Modular Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Worrall, Andrew; Todosow, Michael

    2016-01-01

    Small modular reactors may offer potential benefits, such as enhanced operational flexibility. However, it is vital to understand the holistic impact of small modular reactors on the nuclear fuel cycle and fuel cycle performance. The focus of this paper is on the fuel cycle impacts of light water small modular reactors in a once-through fuel cycle with low-enriched uranium fuel. A key objective of this paper is to describe preliminary reactor core physics and fuel cycle analyses conducted in support of the U.S. Department of Energy Office of Nuclear Energy Fuel Cycle Options Campaign. Challenges with small modular reactors include:more » increased neutron leakage, fewer assemblies in the core (and therefore fewer degrees of freedom in the core design), complex enrichment and burnable absorber loadings, full power operation with inserted control rods, the potential for frequent load-following operation, and shortened core height. Each of these will impact the achievable discharge burn-up in the reactor and the fuel cycle performance. This paper summarizes the results of an expert elicitation focused on developing a list of the factors relevant to small modular reactor fuel, core, and operation that will impact fuel cycle performance. Preliminary scoping analyses were performed using a regulatory-grade reactor core simulator. The hypothetical light water small modular reactor considered in these preliminary scoping studies is a cartridge type one-batch core with 4.9% enrichment. Some core parameters, such as the size of the reactor and general assembly layout, are similar to an example small modular reactor concept from industry. The high-level issues identified and preliminary scoping calculations in this paper are intended to inform on potential fuel cycle impacts of one-batch thermal spectrum SMRs. In particular, this paper highlights the impact of increased neutron leakage and reduced number of batches on the achievable burn-up of the reactor. Fuel cycle performance metrics for a small modular reactor are compared to a conventional three-batch light water reactor in the following areas: nuclear waste management, environmental impact, and resource utilization. Metrics performance for a small modular reactor are degraded for mass of spent nuclear fuel and high level waste disposed, mass of depleted uranium disposed, land use per energy generated, and carbon emission per energy generated« less

  14. Aerosol reactor production of uniform submicron powders

    NASA Technical Reports Server (NTRS)

    Flagan, Richard C. (Inventor); Wu, Jin J. (Inventor)

    1991-01-01

    A method of producing submicron nonagglomerated particles in a single stage reactor includes introducing a reactant or mixture of reactants at one end while varying the temperature along the reactor to initiate reactions at a low rate. As homogeneously small numbers of seed particles generated in the initial section of the reactor progress through the reactor, the reaction is gradually accelerated through programmed increases in temperature along the length of the reactor to promote particle growth by chemical vapor deposition while minimizing agglomerate formation by maintaining a sufficiently low number concentration of particles in the reactor such that coagulation is inhibited within the residence time of particles in the reactor. The maximum temperature and minimum residence time is defined by a combination of temperature and residence time that is necessary to bring the reaction to completion. In one embodiment, electronic grade silane and high purity nitrogen are introduced into the reactor and temperatures of approximately 770.degree. K. to 1550.degree. K. are employed. In another embodiment silane and ammonia are employed at temperatures from 750.degree. K. to 1800.degree. K.

  15. Improvement of anaerobic digestion performance by continuous nitrogen removal with a membrane contactor treating a substrate rich in ammonia and sulfide.

    PubMed

    Lauterböck, B; Nikolausz, M; Lv, Z; Baumgartner, M; Liebhard, G; Fuchs, W

    2014-04-01

    The effect of reduced ammonia levels on anaerobic digestion was investigated. Two reactors were fed with slaughterhouse waste, one with a hollow fiber membrane contractor for ammonia removal and one without. Different organic loading rates (OLR) and free ammonia and sulfide concentrations were investigated. In the reactor with the membrane contactor, the NH4-N concentration was reduced threefold. At a moderate OLR (3.1 kg chemical oxygen demand - COD/m(3)/d), this reactor performed significantly better than the reference reactor. At high OLR (4.2 kg COD/m(3)/d), the reference reactor almost stopped producing methane (0.01 Nl/gCOD). The membrane reactor also showed a stable process with a methane yield of 0.23 Nl/g COD was achieved. Both reactors had predominantly a hydrogenotrophic microbial consortium, however in the membrane reactor the genus Methanosaeta (acetoclastic) was also detected. In general, all relevant parameters and the methanogenic consortium indicated improved anaerobic digestion of the reactor with the membrane. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Control console replacement at the WPI Reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-01-01

    With partial funding from the Department of Energy (DOE) University Reactor Instrumentation Upgrade Program (DOE Grant No. DE-FG02-90ER12982), the original control console at the Worcester Polytechnic Institute (WPI) Reactor has been replaced with a modern system. The new console maintains the original design bases and functionality while utilizing current technology. An advanced remote monitoring system has been added to augment the educational capabilities of the reactor. Designed and built by General Electric in 1959, the open pool nuclear training reactor at WPI was one of the first such facilities in the nation located on a university campus. Devoted to undergraduatemore » use, the reactor and its related facilities have been since used to train two generations of nuclear engineers and scientists for the nuclear industry. The reactor power level was upgraded from 1 to 10 kill in 1969, and its operating license was renewed for 20 years in 1983. In 1988, the reactor was converted to low enriched uranium. The low power output of the reactor and ergonomic facility design make it an ideal tool for undergraduate nuclear engineering education and other training.« less

  17. Aerosol reactor production of uniform submicron powders

    DOEpatents

    Flagan, Richard C.; Wu, Jin J.

    1991-02-19

    A method of producing submicron nonagglomerated particles in a single stage reactor includes introducing a reactant or mixture of reactants at one end while varying the temperature along the reactor to initiate reactions at a low rate. As homogeneously small numbers of seed particles generated in the initial section of the reactor progress through the reactor, the reaction is gradually accelerated through programmed increases in temperature along the length of the reactor to promote particle growth by chemical vapor deposition while minimizing agglomerate formation by maintaining a sufficiently low number concentration of particles in the reactor such that coagulation is inhibited within the residence time of particles in the reactor. The maximum temperature and minimum residence time is defined by a combination of temperature and residence time that is necessary to bring the reaction to completion. In one embodiment, electronic grade silane and high purity nitrogen are introduced into the reactor and temperatures of approximately 770.degree. K. to 1550.degree. K. are employed. In another embodiment silane and ammonia are employed at temperatures from 750.degree. K. to 1800.degree. K.

  18. Oxidative coupling of methane using inorganic membrane reactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ma, Y.H.; Moser, W.R.; Dixon, A.G.

    1995-12-31

    The goal of this research is to improve the oxidative coupling of methane in a catalytic inorganic membrane reactor. A specific target is to achieve conversion of methane to C{sub 2} hydrocarbons at very high selectivity and relatively higher yields than in fixed bed reactors by controlling the oxygen supply through the membrane. A membrane reactor has the advantage of precisely controlling the rate of delivery of oxygen to the catalyst. This facility permits balancing the rate of oxidation and reduction of the catalyst. In addition, membrane reactors minimize the concentration of gas phase oxygen thus reducing non selective gasmore » phase reactions, which are believed to be a main route for formation of CO{sub x} products. Such gas phase reactions are a cause for decreased selectivity in oxidative coupling of methane in conventional flow reactors. Membrane reactors could also produce higher product yields by providing better distribution of the reactant gases over the catalyst than the conventional plug flow reactors. Modeling work which aimed at predicting the observed experimental trends in porous membrane reactors was also undertaken in this research program.« less

  19. Stimulation of the hydrolytic stage for biogas production from cattle manure in an electrochemical bioreactor.

    PubMed

    Samani, Saeed; Abdoli, Mohammad Ali; Karbassi, Abdolreza; Amin, Mohammad Mehdi

    Electrical current in the hydrolytic phase of the biogas process might affect biogas yield. In this study, four 1,150 mL single membrane-less chamber electrochemical bioreactors, containing two parallel titanium plates were connected to the electrical source with voltages of 0, -0.5, -1 and -1.5 V, respectively. Reactor 1 with 0 V was considered as a control reactor. The trend of biogas production was precisely checked against pH, oxidation reduction potential and electrical power at a temperature of 37 ± 0.5°C amid cattle manure as substrate for 120 days. Biogas production increased by voltage applied to Reactors 2 and 3 when compared with the control reactor. In addition, the electricity in Reactors 2 and 3 caused more biogas production than Reactor 4. Acetogenic phase occurred more quickly in Reactor 3 than in the other reactors. The obtained results from Reactor 4 were indicative of acidogenic domination and its continuous behavior under electrical stimulation. The results of the present investigation clearly revealed that phasic electrical current could enhance the efficiency of biogas production.

  20. Comparative study between single core model and detail core model of CFD modelling on reactor core cooling behaviour

    NASA Astrophysics Data System (ADS)

    Darmawan, R.

    2018-01-01

    Nuclear power industry is facing uncertainties since the occurrence of the unfortunate accident at Fukushima Daiichi Nuclear Power Plant. The issue of nuclear power plant safety becomes the major hindrance in the planning of nuclear power program for new build countries. Thus, the understanding of the behaviour of reactor system is very important to ensure the continuous development and improvement on reactor safety. Throughout the development of nuclear reactor technology, investigation and analysis on reactor safety have gone through several phases. In the early days, analytical and experimental methods were employed. For the last four decades 1D system level codes were widely used. The continuous development of nuclear reactor technology has brought about more complex system and processes of nuclear reactor operation. More detailed dimensional simulation codes are needed to assess these new reactors. Recently, 2D and 3D system level codes such as CFD are being explored. This paper discusses a comparative study on two different approaches of CFD modelling on reactor core cooling behaviour.

  1. Void effect analysis of Pb-208 of fast reactors with modified CANDLE burn-up scheme

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Widiawati, Nina, E-mail: nina-widiawati28@yahoo.com; Su’ud, Zaki, E-mail: szaki@fi.itb.ac.id

    Void effect analysis of Pb-208 as coolant of fast reactors with modified candle burn-up scheme has been conducted. Lead cooled fast reactor (LFR) is one of the fourth-generation reactor designs. The reactor is designed with a thermal power output of 500 MWt. Modified CANDLE burn-up scheme allows the reactor to have long life operation by supplying only natural uranium as fuel cycle input. This scheme introducing discrete region, the fuel is initially put in region 1, after one cycle of 10 years of burn up it is shifted to region 2 and region 1 is filled by fresh natural uraniummore » fuel. The reactor is designed for 100 years with 10 regions arranged axially. The results of neutronic calculation showed that the void coefficients ranged from −0.6695443 % at BOC to −0.5273626 % at EOC for 500 MWt reactor. The void coefficients of Pb-208 more negative than Pb-nat. The results showed that the reactors with Pb-208 coolant have better level of safety than Pb-nat.« less

  2. Five Lectures on Nuclear Reactors Presented at Cal Tech

    DOE R&D Accomplishments Database

    Weinberg, Alvin M.

    1956-02-10

    The basic issues involved in the physics and engineering of nuclear reactors are summarized. Topics discussed include theory of reactor design, technical problems in power reactors, physical problems in nuclear power production, and future developments in nuclear power. (C.H.)

  3. 10 CFR 2.102 - Administrative review of application.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of...) The Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office... Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES OF PRACTICE AND PROCEDURE Procedure for Issuance...

  4. 10 CFR 2.102 - Administrative review of application.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office of...) The Director, Office of Nuclear Reactor Regulation, Director, Office of New Reactors, Director, Office... Energy NUCLEAR REGULATORY COMMISSION AGENCY RULES OF PRACTICE AND PROCEDURE Procedure for Issuance...

  5. Proceedings of the 1992 topical meeting on advances in reactor physics. Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-04-01

    This document, Volume 2, presents proceedings of the 1992 Topical Meeting on Advances in Reactor Physics on March 8--11, 1992 at Charleston, SC. Session topics were as follows: Transport Theory; Fast Reactors; Plant Analyzers; Integral Experiments/Measurements & Analysis; Core Computational Systems; Reactor Physics; Monte Carlo; Safety Aspects of Heavy Water Reactors; and Space-Time Core Kinetics. The individual reports have been cataloged separately. (FI)

  6. Navy Nuclear-Powered Surface Ships: Background, Issues, and Options for Congress

    DTIC Science & Technology

    2010-06-10

    scale pressurized water reactors suitable for destroyer-sized vessels or for alternative nuclear power systems using thorium liquid salt technology...or to design a new reactor type potentially using a thorium liquid salt reactor developed for maritime use. The committee recommends an increase of...either using a pressurized water reactor or a thorium liquid salt reactor . (Page 158) Senate The Senate Armed Services Committee, in its report

  7. Reactor monitoring using antineutrino detectors

    NASA Astrophysics Data System (ADS)

    Bowden, N. S.

    2011-08-01

    Nuclear reactors have served as the antineutrino source for many fundamental physics experiments. The techniques developed by these experiments make it possible to use these weakly interacting particles for a practical purpose. The large flux of antineutrinos that leaves a reactor carries information about two quantities of interest for safeguards: the reactor power and fissile inventory. Measurements made with antineutrino detectors could therefore offer an alternative means for verifying the power history and fissile inventory of a reactor as part of International Atomic Energy Agency (IAEA) and/or other reactor safeguards regimes. Several efforts to develop this monitoring technique are underway worldwide.

  8. CONVECTION REACTOR

    DOEpatents

    Hammond, R.P.; King, L.D.P.

    1960-03-22

    An homogeneous nuclear power reactor utilizing convection circulation of the liquid fuel is proposed. The reactor has an internal heat exchanger looated in the same pressure vessel as the critical assembly, thereby eliminating necessity for handling the hot liquid fuel outside the reactor pressure vessel during normal operation. The liquid fuel used in this reactor eliminates the necessity for extensive radiolytic gas rocombination apparatus, and the reactor is resiliently pressurized and, without any movable mechanical apparatus, automatically regulates itself to the condition of criticality during moderate variations in temperature snd pressure and shuts itself down as the pressure exceeds a predetermined safe operating value.

  9. Chip-based device for parallel sorting, amplification, detection, and identification of nucleic acid subsequences

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beer, Neil Reginald; Colston, Jr, Billy W.

    An apparatus for chip-based sorting, amplification, detection, and identification of a sample having a planar substrate. The planar substrate is divided into cells. The cells are arranged on the planar substrate in rows and columns. Electrodes are located in the cells. A micro-reactor maker produces micro-reactors containing the sample. The micro-reactor maker is positioned to deliver the micro-reactors to the planar substrate. A microprocessor is connected to the electrodes for manipulating the micro-reactors on the planar substrate. A detector is positioned to interrogate the sample contained in the micro-reactors.

  10. Design and evaluation of experimental ceramic automobile thermal reactors

    NASA Technical Reports Server (NTRS)

    Stone, P. L.; Blankenship, C. P.

    1974-01-01

    The paper summarizes the results obtained in an exploratory evaluation of ceramics for automobile thermal reactors. Candidate ceramic materials were evaluated in several reactor designs using both engine dynamometer and vehicle road tests. Silicon carbide contained in a corrugated metal support structure exhibited the best performance, lasting 1100 hours in engine dynamometer tests and for more than 38,600 kilimeters (24,000 miles) in vehicle road tests. Although reactors containing glass-ceramic components did not perform as well as silicon carbide, the glass-ceramics still offer good potential for reactor use with improved reactor designs.

  11. Design and evaluation of experimental ceramic automobile thermal reactors

    NASA Technical Reports Server (NTRS)

    Stone, P. L.; Blankenship, C. P.

    1974-01-01

    The results obtained in an exploratory evaluation of ceramics for automobile thermal reactors are summarized. Candidate ceramic materials were evaluated in several reactor designs by using both engine-dynamometer and vehicle road tests. Silicon carbide contained in a corrugated-metal support structure exhibited the best performance, lasting 1100 hr in engine-dynamometer tests and more than 38,600 km (24000 miles) in vehicle road tests. Although reactors containing glass-ceramic components did not perform as well as those containing silicon carbide, the glass-ceramics still offer good potential for reactor use with improved reactor designs.

  12. On Study of Application of Micro-reactor in Chemistry and Chemical Field

    NASA Astrophysics Data System (ADS)

    Zhang, Yunshen

    2018-02-01

    Serving as a micro-scale chemical reaction system, micro-reactor is characterized by high heat transfer efficiency and mass transfer, strictly controlled reaction time and good safety performance; compared with the traditional mixing reactor, it can effectively shorten reaction time by virtue of these advantages and greatly enhance the chemical reaction conversion rate. However, problems still exist in the process where micro-reactor is used for production in chemistry and chemical field, and relevant researchers are required to optimize and perfect the performance of micro-reactor. This paper analyzes specific application of micro-reactor in chemistry and chemical field.

  13. The results of systems tests of the 500 kV busbar controllable shunting reactor in the Tavricheskaya substation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gusev, S. I.; Karpov, V. N.; Kiselev, A. N.

    2009-09-15

    The results of systems tests of the 500 kV busbar magnetization-controllable shunting reactor (CSR), set up in the Tavricheskaya substation, including measurements of the quality of the electric power, the harmonic composition of the network currents of the reactor for different values of the reactive power consumed, the determination of the regulating characteristics of the reactor, the speed of response of the shunting reactor in the current and voltage stabilization modes, and also the operation of the reactor under dynamic conditions for different perturbations, are presented. The results obtained are analyzed.

  14. Evolution of the collective radiation dose of nuclear reactors from the 2nd through to the 3rd generation and 4th generation sodium-cooled fast reactors

    NASA Astrophysics Data System (ADS)

    Guidez, Joel; Saturnin, Anne

    2017-11-01

    During the operation of a nuclear reactor, the external individual doses received by the personnel are measured and recorded, in conformity with the regulations in force. The sum of these measurements enables an evaluation of the annual collective dose expressed in man·Sv/year. This information is a useful tool when comparing the different design types and reactors. This article discusses the evolution of the collective dose for several types of reactors, mainly based on publications from the NEA and the IAEA. The spread of good practices (optimization of working conditions and of the organization, sharing of lessons learned, etc.) and ongoing improvements in reactor design have meant that over time, the doses of various origins received by the personnel have decreased. In the case of sodium-cooled fast reactors (SFRs), the compilation and summarizing of various documentary resources has enabled them to be situated and compared to other types of reactors of the second and third generations (respectively pressurized water reactors in operation and EPR under construction). From these results, it can be seen that the doses received during the operation of SFR are significantly lower for this type of reactor.

  15. 454 pyrosequencing analyses of bacterial and archaeal richness in 21 full-scale biogas digesters.

    PubMed

    Sundberg, Carina; Al-Soud, Waleed A; Larsson, Madeleine; Alm, Erik; Yekta, Sepehr S; Svensson, Bo H; Sørensen, Søren J; Karlsson, Anna

    2013-09-01

    The microbial community of 21 full-scale biogas reactors was examined using 454 pyrosequencing of 16S rRNA gene sequences. These reactors included seven (six mesophilic and one thermophilic) digesting sewage sludge (SS) and 14 (ten mesophilic and four thermophilic) codigesting (CD) various combinations of wastes from slaughterhouses, restaurants, households, etc. The pyrosequencing generated more than 160,000 sequences representing 11 phyla, 23 classes, and 95 genera of Bacteria and Archaea. The bacterial community was always both more abundant and more diverse than the archaeal community. At the phylum level, the foremost populations in the SS reactors included Actinobacteria, Proteobacteria, Chloroflexi, Spirochetes, and Euryarchaeota, while Firmicutes was the most prevalent in the CD reactors. The main bacterial class in all reactors was Clostridia. Acetoclastic methanogens were detected in the SS, but not in the CD reactors. Their absence suggests that methane formation from acetate takes place mainly via syntrophic acetate oxidation in the CD reactors. A principal component analysis of the communities at genus level revealed three clusters: SS reactors, mesophilic CD reactors (including one thermophilic CD and one SS), and thermophilic CD reactors. Thus, the microbial composition was mainly governed by the substrate differences and the process temperature. © 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  16. Application of a novel type impinging streams reactor in solid-liquid enzyme reactions and modeling of residence time distribution using GDB model.

    PubMed

    Fatourehchi, Niloufar; Sohrabi, Morteza; Dabir, Bahram; Royaee, Sayed Javid; Haji Malayeri, Adel

    2014-02-05

    Solid-liquid enzyme reactions constitute important processes in biochemical industries. The isomerization of d-glucose to d-fructose, using the immobilized glucose isomerase (Sweetzyme T), as a typical example of solid-liquid catalyzed reactions has been carried out in one stage and multi-stage novel type of impinging streams reactors. Response surface methodology was applied to determine the effects of certain pertinent parameters of the process namely axial velocity (A), feed concentration (B), nozzles' flow rates (C) and enzyme loading (D) on the performance of the apparatus. The results obtained from the conversion of glucose in this reactor were much higher than those expected in conventional reactors, while residence time was decreased dramatically. Residence time distribution (RTD) in a one-stage impinging streams reactor was investigated using colored solution as the tracer. The results showed that the flow pattern in the reactor was close to that in a continuous stirred tank reactor (CSTR). Based on the analysis of flow region in the reactor, gamma distribution model with bypass (GDB) was applied to study the RTD of the reactor. The results indicated that RTD in the impinging streams reactor could be described by the latter model. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Enhanced biodegradation of hexachlorocyclohexane in upflow anaerobic sludge blanket reactor using methanol as an electron donor.

    PubMed

    Bhatt, Praveena; Kumar, M Suresh; Mudliar, Sandeep; Chakrabarti, Tapan

    2008-05-01

    Anaerobic dechlorination of technical grade hexachlorocyclohexane (THCH) was studied in a continuous upflow anaerobic sludge blanket (UASB) reactor with methanol as a supplementary substrate and electron donor. A reactor without methanol served as the experimental control. The inlet feed concentration of THCH in both the experimental and the control UASB reactor was 100 mg l(-1). After 60 days of continuous operation, the removal of THCH was >99% in the methanol-supplemented reactor as compared to 20-35% in the control reactor. THCH was completely dechlorinated in the methanol fed reactor at 48 h HRT after 2 months of continuous operation. This period was also accompanied by increase in biomass in the reactor, which was not observed in the experimental control. Batch studies using other supplementary substrates as well as electron donors namely acetate, butyrate, formate and ethanol showed lower % dechlorination (<85%) and dechlorination rates (<3 mg g(-1)d(-1)) as compared to methanol (98%, 5 mg g(-1)d(-1)). The optimum concentration of methanol required, for stable dechlorination of THCH (100 mg l(-1)) in the UASB reactor, was found to be 500 mg l(-1). Results indicate that addition of methanol as electron donor enhances dechlorination of THCH at high inlet concentration, and is also required for stable UASB reactor performance.

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nygaard, E. T.; Williams, M. M. R.; Angelo, P. L.

    Babcock and Wilcox Technical Services Group (B and W) has identified aqueous homogeneous reactors (AHRs) as a technology well suited to produce the medical isotope molybdenum 99 (Mo-99). AHRs have never been specifically designed or built for this specialized purpose. However, AHRs have a proven history of being safe research reactors. In fact, in 1958, AHRs had 'a longer history of operation than any other type of research reactor using enriched fuel' and had 'experimentally demonstrated to be among the safest of all various type of research reactor now in use [1].' A 'Level 1' model representing B and W'smore » proposed Medical Isotope Production System (MIPS) reactor has been developed. The Level 1 model couples a series of differential equations representing neutronics, temperature, and voiding. Neutronics are represented by point reactor kinetics while temperature and voiding terms are axially varying (one-dimensional). While this model was developed specifically for the MIPS reactor, its applicability to the Japanese TRACY reactor was assessed. The results from the Level 1 model were in good agreement with TRACY experimental data and found to be conservative over most of the time domains considered. The Level 1 model was used to study the MIPS reactor. An analysis showed the Level 1 model agreed well with a more complex computational model of the MIPS reactor (a FETCH model). Finally, a significant reactivity insertion was simulated with the Level 1 model to study the MIPS reactor's time-dependent response. (authors)« less

  19. Consumption of the electric power inside silent discharge reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yehia, Ashraf, E-mail: yehia30161@yahoo.com

    An experimental study was made in this paper to investigate the relation between the places of the dielectric barriers, which cover the surfaces of the electrodes in the coaxial cylindrical reactors, and the rate of change of the electric power that is consumed in forming silent discharges. Therefore, silent discharges have been formed inside three coaxial cylindrical reactors. The dielectric barriers in these reactors were pasted on both the internal surface of the outer electrode in the first reactor and the external surface of the inner electrode in the second reactor as well as the surfaces of the two electrodesmore » in the third reactor. The reactor under study has been fed by atmospheric air that flowed inside it with a constant rate at normal temperature and pressure, in parallel with the application of a sinusoidal ac voltage between the electrodes of the reactor. The electric power consumed in forming the silent discharges inside the three reactors was measured as a function of the ac peak voltage. The validity of the experimental results was investigated by applying Manley's equation on the same discharge conditions. The results have shown that the rate of consumption of the electric power relative to the ac peak voltage per unit width of the discharge gap improves by a ratio of either 26.8% or 80% or 128% depending on the places of the dielectric barriers that cover the surfaces of the electrodes inside the three reactors.« less

  20. Reactor Operations Monitoring System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hart, M.M.

    1989-01-01

    The Reactor Operations Monitoring System (ROMS) is a VME based, parallel processor data acquisition and safety action system designed by the Equipment Engineering Section and Reactor Engineering Department of the Savannah River Site. The ROMS will be analyzing over 8 million signal samples per minute. Sixty-eight microprocessors are used in the ROMS in order to achieve a real-time data analysis. The ROMS is composed of multiple computer subsystems. Four redundant computer subsystems monitor 600 temperatures with 2400 thermocouples. Two computer subsystems share the monitoring of 600 reactor coolant flows. Additional computer subsystems are dedicated to monitoring 400 signals from assortedmore » process sensors. Data from these computer subsystems are transferred to two redundant process display computer subsystems which present process information to reactor operators and to reactor control computers. The ROMS is also designed to carry out safety functions based on its analysis of process data. The safety functions include initiating a reactor scram (shutdown), the injection of neutron poison, and the loadshed of selected equipment. A complete development Reactor Operations Monitoring System has been built. It is located in the Program Development Center at the Savannah River Site and is currently being used by the Reactor Engineering Department in software development. The Equipment Engineering Section is designing and fabricating the process interface hardware. Upon proof of hardware and design concept, orders will be placed for the final five systems located in the three reactor areas, the reactor training simulator, and the hardware maintenance center.« less

  1. A brief history of design studies on innovative nuclear reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sekimoto, Hiroshi, E-mail: hsekimot@gmail.com

    2014-09-30

    In a short period after the success of CP1, many types of nuclear reactors were proposed and investigated. However, soon only a small number of reactors were selected for practical use. Around 1970, only LWRs with small number of CANDUs were operated in the western world, and FBRs were under development. It was about the time when Apollo moon landing was accomplished. However, at the same time, the future of human being was widely considered pessimistic and Limits to Growth was published. In the end of 1970’s the TMI accident occurred and many nuclear reactor contracts were cancelled in USAmore » and any more contracts had not been concluded until recent years. From the reflection of this accident, many Inherent Safe Reactors (ISRs) were proposed, though none of them were constructed. A common idea of ISRs is smallness of their size. Tokyo Institute of Technology (TokyoTech) held a symposium on small reactors, SR/TIT, in 1991, where many types of small ISRs were presented. Recently small reactors attract interest again. The most ideas employed in these reactors were the same discussed in SR/TIT. In 1980’s the radioactive wastes from fuel cycle became a severe problem around the world. In TokyoTech, this issue was discussed mainly from the viewpoint of nuclear transmutations. The neutron economy became inevitable for these innovative nuclear reactors especially small long-life reactors and transmutation reactors.« less

  2. A new safety channel based on ¹⁷N detection in research reactors.

    PubMed

    Seyfi, Somayye; Gharib, Morteza

    2015-10-01

    Tehran research reactor (TRR) is a representative of pool type research reactors using light water, as coolant and moderator. This reactor is chosen as a prototype to demonstrate and prove the feasibility of (17)N detection as a new redundant channel for reactor power measurement. In TRR, similar to other pool type reactors, neutron detectors are immersed in the pool around the core as the main power measuring devices. In the present article, a different approach, using out of water neutron detector, is employed to measure reactor power. This new method is based on (17)O (n,p) (17)N reaction taking place inside the core and subsequent measurement of delayed neutrons emitted due to (17)N disintegration. Count and measurement of neutrons around outlet water pipe provides a reliable redundant safety channel to measure reactor power. Results compared with other established channels indicate a good agreement and shows a linear interdependency with true thermal power. Safety of reactor operation is improved with installation & use of this new power measuring channel. The new approach may equally serve well as a redundant channel in all other types of reactors having coolant comprised of oxygen in its molecular constituents. Contrary to existing channels, this one is totally out of water and thus is an advantage over current instrumentations. It is proposed to employ the same idea on other reactors (nuclear power plants too) to improve safety criteria. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. 75 FR 21046 - Advisory Committee on Reactor Safeguards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-22

    ... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards In accordance with the... on Reactor Safeguards (ACRS) will hold a meeting on May 6-8, 2010, 11545 Rockville Pike, Rockville....: Boiling Water Reactor (BWR) Owners Group (BWROG) Topical Report NEDC-33347P, ``Containment Overpressure...

  4. Thermionic reactors for space nuclear power

    NASA Technical Reports Server (NTRS)

    Homeyer, W. G.; Merrill, M. H.; Holland, J. W.; Fisher, C. R.; Allen, D. T.

    1985-01-01

    Thermionic reactor designs for a variety of space power applications spanning the range from 5 kWe to 3 MWe are described. In all of these reactors, nuclear heat is converted directly to electrical energy in thermionic fuel elements (TFEs). A circulating reactor coolant carries heat from the core of TFEs directly to a heat rejection radiator system. The recent design of a thermionic reactor to meet the SP-100 requirements is emphasized. Design studies of reactors at other power levels show that the same TFE can be used over a broad range in power, and that design modifications can extend the range to many megawatts. The design of the SP-100 TFE is similar to that of TFEs operated successfully in test reactors, but with design improvements to extend the operating lifetime to seven years.

  5. Axi-symmetrical flow reactor for .sup.196 Hg photochemical enrichment

    DOEpatents

    Grossman, Mark W.

    1991-01-01

    The present invention is directed to an improved photochemical reactor useful for the isotopic enrichment of a predetermined isotope of mercury, especially, .sup.196 Hg. Specifically, two axi-symmetrical flow reactors were constructed according to the teachings of the present invention. These reactors improve the mixing of the reactants during the photochemical enrichment process, affording higher yields of the desired .sup.196 Hg product. Measurements of the variation of yield (Y) and enrichment factor (E) along the flow axis of these reactors indicates very substantial improvement in process uniformity compared to previously used photochemical reactor systems. In one preferred embodiment of the present invention, the photoreactor system was built such that the reactor chamber was removable from the system without disturbing the location of either the photochemical lamp or the filter employed therewith.

  6. Applications of plasma core reactors to terrestrial energy systems

    NASA Technical Reports Server (NTRS)

    Latham, T. S.; Biancardi, F. R.; Rodgers, R. J.

    1974-01-01

    Plasma core reactors offer several new options for future energy needs in addition to space power and propulsion applications. Power extraction from plasma core reactors with gaseous nuclear fuel allows operation at temperatures higher than conventional reactors. Highly efficient thermodynamic cycles and applications employing direct coupling of radiant energy are possible. Conceptual configurations of plasma core reactors for terrestrial applications are described. Closed-cycle gas turbines, MHD systems, photo- and thermo-chemical hydrogen production processes, and laser systems using plasma core reactors as prime energy sources are considered. Cycle efficiencies in the range of 50 to 65 percent are calculated for closed-cycle gas turbine and MHD electrical generators. Reactor advantages include continuous fuel reprocessing which limits inventory of radioactive by-products and thorium-U-233 breeder configurations with about 5-year doubling times.-

  7. Grey water treatment in upflow anaerobic sludge blanket (UASB) reactor at different temperatures.

    PubMed

    Elmitwalli, Tarek; Otterpohl, Ralf

    2011-01-01

    The treatment of grey water in two upflow anaerobic sludge blanket (UASB) reactors, operated at different hydraulic retention times (HRTs) and temperatures, was investigated. The first reactor (UASB-A) was operated at ambient temperature (14-25 degrees C) and HRT of 20, 12 and 8 h, while the second reactor (UASB-30) was operated at controlled temperature of 30 degrees C and HRT of 16, 10 and 6 h. The two reactors were fed with grey water from 'Flintenbreite' settlement in Luebeck, Germany. When the grey water was treated in the UASB reactor at 30 degrees C, total chemical oxygen demand (CODt) removal of 52-64% was achieved at HRT between 6 and 16 h, while at lower temperature lower removal (31-41%) was obtained at HRT between 8 and 20 h. Total nitrogen and phosphorous removal in the UASB reactors were limited (22-36 and 10-24%, respectively) at all operational conditions. The results showed that at increasing temperature or decreasing HRT of the reactors, maximum specific methanogenic activity of the sludge in the reactors improved. As the UASB reactor showed a significantly higher COD removal (31-64%) than the septic tank (11-14%) even at low temperature, it is recommended to use UASB reactor instead of septic tank (the most common system) for grey water pre-treatment. Based on the achieved results and due to high peak flow factor, a HRT between 8 and 12 h can be considered the suitable HRT for the UASB reactor treating grey water at temperature 20-30 degrees C, while a HRT of 12-24 h can be applied at temperature lower than 20 degrees C.

  8. Optimization of post-column reactor radius in capillary high performance liquid chromatography Effect of chromatographic column diameter and particle diameter

    PubMed Central

    Xu, Hongjuan; Weber, Stephen G.

    2006-01-01

    A post-column reactor consisting of a simple open tube (Capillary Taylor Reactor) affects the performance of a capillary LC in two ways: stealing pressure from the column and adding band spreading. The former is a problem for very small radius reactors, while the latter shows itself for large reactor diameters. We derived an equation that defines the observed number of theoretical plates (Nobs) taking into account the two effects stated above. Making some assumptions and asserting certain conditions led to a final equation with a limited number of variables, namely chromatographic column radius, reactor radius and chromatographic particle diameter. The assumptions and conditions are that the van Deemter equation applies, the mass transfer limitation is for intraparticle diffusion in spherical particles, the velocity is at the optimum, the analyte’s retention factor, k′, is zero, the post-column reactor is only long enough to allow complete mixing of reagents and analytes and the maximum operating pressure of the pumping system is used. Optimal ranges of the reactor radius (ar) are obtained by comparing the number of observed theoretical plates (and theoretical plates per time) with and without a reactor. Results show that the acceptable reactor radii depend on column diameter, particle diameter, and maximum available pressure. Optimal ranges of ar become narrower as column diameter increases, particle diameter decreases or the maximum pressure is decreased. When the available pressure is 4000 psi, a Capillary Taylor Reactor with 12 μm radius is suitable for all columns smaller than 150 μm (radius) packed with 2–5 μm particles. For 1 μm packing particles, only columns smaller than 42.5 μm (radius) can be used and the reactor radius needs to be 5 μm. PMID:16494886

  9. Experimental study of radiation dose rate at different strategic points of the BAEC TRIGA Research Reactor.

    PubMed

    Ajijul Hoq, M; Malek Soner, M A; Salam, M A; Haque, M M; Khanom, Salma; Fahad, S M

    2017-12-01

    The 3MW TRIGA Mark-II Research Reactor of Bangladesh Atomic Energy Commission (BAEC) has been under operation for about thirty years since its commissioning at 1986. In accordance with the demand of fundamental nuclear research works, the reactor has to operate at different power levels by utilizing a number of experimental facilities. Regarding the enquiry for safety of reactor operating personnel and radiation workers, it is necessary to know the radiation level at different strategic points of the reactor where they are often worked. In the present study, neutron, beta and gamma radiation dose rate at different strategic points of the reactor facility with reactor power level of 2.4MW was measured to estimate the rising level of radiation due to its operational activities. From the obtained results high radiation dose is observed at the measurement position of the piercing beam port which is caused by neutron leakage and accordingly, dose rate at the stated position with different reactor power levels was measured. This study also deals with the gamma dose rate measurements at a fixed position of the reactor pool top surface for different reactor power levels under both Natural Convection Cooling Mode (NCCM) and Forced Convection Cooling Mode (FCCM). Results show that, radiation dose rate is higher for NCCM in compared with FCCM and increasing with the increase of reactor power. Thus, concerning the radiological safety issues for working personnel and the general public, the radiation dose level monitoring and the experimental analysis performed within this paper is so much effective and the result of this work can be utilized for base line data and code verification of the nuclear reactor. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Validation of large-scale, monochromatic UV disinfection systems for drinking water using dyed microspheres.

    PubMed

    Blatchley, E R; Shen, C; Scheible, O K; Robinson, J P; Ragheb, K; Bergstrom, D E; Rokjer, D

    2008-02-01

    Dyed microspheres have been developed as a new method for validation of ultraviolet (UV) reactor systems. When properly applied, dyed microspheres allow measurement of the UV dose distribution delivered by a photochemical reactor for a given operating condition. Prior to this research, dyed microspheres had only been applied to a bench-scale UV reactor. The goal of this research was to extend the application of dyed microspheres to large-scale reactors. Dyed microsphere tests were conducted on two prototype large-scale UV reactors at the UV Validation and Research Center of New York (UV Center) in Johnstown, NY. All microsphere tests were conducted under conditions that had been used previously in biodosimetry experiments involving two challenge bacteriophage: MS2 and Qbeta. Numerical simulations based on computational fluid dynamics and irradiance field modeling were also performed for the same set of operating conditions used in the microspheres assays. Microsphere tests on the first reactor illustrated difficulties in sample collection and discrimination of microspheres against ambient particles. Changes in sample collection and work-up were implemented in tests conducted on the second reactor that allowed for improvements in microsphere capture and discrimination against the background. Under these conditions, estimates of the UV dose distribution from the microspheres assay were consistent with numerical simulations and the results of biodosimetry, using both challenge organisms. The combined application of dyed microspheres, biodosimetry, and numerical simulation offers the potential to provide a more in-depth description of reactor performance than any of these methods individually, or in combination. This approach also has the potential to substantially reduce uncertainties in reactor validation, thereby leading to better understanding of reactor performance, improvements in reactor design, and decreases in reactor capital and operating costs.

  11. BOILING REACTORS

    DOEpatents

    Untermyer, S.

    1962-04-10

    A boiling reactor having a reactivity which is reduced by an increase in the volume of vaporized coolant therein is described. In this system unvaporized liquid coolant is extracted from the reactor, heat is extracted therefrom, and it is returned to the reactor as sub-cooled liquid coolant. This reduces a portion of the coolant which includes vaporized coolant within the core assembly thereby enhancing the power output of the assembly and rendering the reactor substantially self-regulating. (AEC)

  12. Period meter for reactors

    DOEpatents

    Rusch, Gordon K.

    1976-01-06

    An improved log N amplifier type nuclear reactor period meter with reduced probability for noise-induced scrams is provided. With the reactor at low power levels a sampling circuit is provided to determine the reactor period by measuring the finite change in the amplitude of the log N amplifier output signal for a predetermined time period, while at high power levels, differentiation of the log N amplifier output signal provides an additional measure of the reactor period.

  13. PBF Reactor Building (PER620). After lowering reactor vessel onto blocks, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PBF Reactor Building (PER-620). After lowering reactor vessel onto blocks, it is rolled on logs into PBF. Metal framework under vessel is handling device. Various penetrations in reactor bottom were for instrumentation, poison injection, drains. Large one, below center "manhole" was for primary coolant. Photographer: Larry Page. Date: February 13, 1970. INEEL negative no. 70-736 - Idaho National Engineering Laboratory, SPERT-I & Power Burst Facility Area, Scoville, Butte County, ID

  14. Liquid metal cooled nuclear reactor plant system

    DOEpatents

    Hunsbedt, Anstein; Boardman, Charles E.

    1993-01-01

    A liquid metal cooled nuclear reactor having a passive cooling system for removing residual heat resulting for fuel decay during reactor shutdown, or heat produced during a mishap. The reactor system is enhanced with sealing means for excluding external air from contact with the liquid metal coolant leaking from the reactor vessel during an accident. The invention also includes a silo structure which resists attack by leaking liquid metal coolant, and an added unique cooling means.

  15. Modelling of the anti-neutrino production and spectra from a Magnox reactor

    NASA Astrophysics Data System (ADS)

    Mills, Robert W.; Mountford, David J.; Coleman, Jonathon P.; Metelko, Carl; Murdoch, Matthew; Schnellbach, Yan-Jie

    2018-01-01

    The anti-neutrino source properties of a fission reactor are governed by the production and beta decay of the radionuclides present and the summation of their individual anti-neutrino spectra. The fission product radionuclide production changes during reactor operation and different fissioning species give rise to different product distributions. It is thus possible to determine some details of reactor operation, such as power, from the anti-neutrino emission to confirm safeguards records. Also according to some published calculations, it may be feasible to observe different anti-neutrino spectra depending on the fissile contents of the reactor fuel and thus determine the reactor's fissile material inventory during operation which could considerable improve safeguards. In mid-2014 the University of Liverpool deployed a prototype anti-neutrino detector at the Wylfa R1 station in Anglesey, United Kingdom based upon plastic scintillator technology developed for the T2K project. The deployment was used to develop the detector electronics and software until the reactor was finally shutdown in December 2015. To support the development of this detector technology for reactor monitoring and to understand its capabilities, the National Nuclear Laboratory modelled this graphite moderated and natural uranium fuelled reactor with existing codes used to support Magnox reactor operations and waste management. The 3D multi-physics code PANTHER was used to determine the individual powers of each fuel element (8×6152) during the year and a half period of monitoring based upon reactor records. The WIMS/TRAIL/FISPIN code route was then used to determine the radionuclide inventory of each nuclide on a daily basis in each element. These nuclide inventories were then used with the BTSPEC code to determine the anti-neutrino spectra and source strength using JEFF-3.1.1 data. Finally the anti-neutrino source from the reactor for each day during the year and a half of monitored reactor operation was calculated. The results of the preliminary calculations are shown and limitations in the methods and data discussed.

  16. NASA Reactor Facility Hazards Summary. Volume 1

    NASA Technical Reports Server (NTRS)

    1959-01-01

    The Lewis Research Center of the National Aeronautics and Space Administration proposes to build a nuclear research reactor which will be located in the Plum Brook Ordnance Works near Sandusky, Ohio. The purpose of this report is to inform the Advisory Committee on Reactor Safeguards of the U. S. Atomic Energy Commission in regard to the design Lq of the reactor facility, the characteristics of the site, and the hazards of operation at this location. The purpose of this research reactor is to make pumped loop studies of aircraft reactor fuel elements and other reactor components, radiation effects studies on aircraft reactor materials and equipment, shielding studies, and nuclear and solid state physics experiments. The reactor is light water cooled and moderated of the MTR-type with a primary beryllium reflector and a secondary water reflector. The core initially will be a 3 by 9 array of MTR-type fuel elements and is designed for operation up to a power of 60 megawatts. The reactor facility is described in general terms. This is followed by a discussion of the nuclear characteristics and performance of the reactor. Then details of the reactor control system are discussed. A summary of the site characteristics is then presented followed by a discussion of the larger type of experiments which may eventually be operated in this facility. The considerations for normal operation are concluded with a proposed method of handling fuel elements and radioactive wastes. The potential hazards involved with failures or malfunctions of this facility are considered in some detail. These are examined first from the standpoint of preventing them or minimizing their effects and second from the standpoint of what effect they might have on the reactor facility staff and the surrounding population. The most essential feature of the design for location at the proposed site is containment of the maximum credible accident.

  17. Investigation of the effects of radiolytic-gas bubbles on the long-term operation of solution reactors for medical-isotope production

    NASA Astrophysics Data System (ADS)

    Souto Mantecon, Francisco Javier

    One of the most common and important medical radioisotopes is 99Mo, which is currently produced using the target irradiation technology in heterogeneous nuclear reactors. The medical isotope 99Mo can also be produced from uranium fission using aqueous homogeneous solution reactors. In solution reactors, 99Mo is generated directly in the fuel solution, resulting in potential advantages when compared with the target irradiation process in heterogeneous reactors, such as lower reactor power, less waste heat, and reduction by a factor of about 100 in the generation of spent fuel. The commercial production of medical isotopes in solution reactors requires steady-state operation at about 200 kW. At this power regime, the formation of radiolytic-gas bubbles creates a void volume in the fuel solution that introduces a negative coefficient of reactivity, resulting in power reduction and instabilities that may impede reactor operation for medical-isotope production. A model has been developed considering that reactivity effects are due to the increase in the fuel-solution temperature and the formation of radiolytic-gas bubbles. The model has been validated against experimental results from the Los Alamos National Laboratory uranyl fluoride Solution High-Energy Burst Assembly (SHEBA), and the SILENE uranyl nitrate solution reactor, commissioned at the Commissariat a l'Energie Atomique, in Valduc, France. The model shows the feasibility of solution reactors for the commercial production of medical isotopes and reveals some of the important parameters to consider in their design, including the fuel-solution type, 235U enrichment, uranium concentration, reactor vessel geometry, and neutron reflectors surrounding the reactor vessel. The work presented herein indicates that steady-state operation at 200 kW can be achieved with a solution reactor consisting of 120 L of uranyl nitrate solution enriched up to 20% with 235U and a uranium concentration of 145 kg/m3 in a graphite-reflected cylindrical geometry.

  18. The RERTR Program status and progress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Travelli, A.

    1995-12-01

    The progress of the Reduced Enrichment Research and Test Reactor (RERTR) Program is described. The major events, findings, and activities of 1995 are reviewed after a brief summary of the results which the RERTR Program had achieved by the end of 1994. The revelation that Iraq was on the verge of developing a nuclear weapon at the time of the Gulf War, and that it was planning to do so by extracting HEU from the fuel of its research reactors, has given new impetus and urgency to the RERTR commitment of eliminating HEU use in research and test reactors worldwide.more » Development of advanced LEU research reactor fuels is scheduled to begin in October 1995. The Russian RERTR program, which aims to develop and demonstrate within the next five years the technical means needed to convert Russian-supplied research reactors to LEU fuels, is now in operation. A Statement of Intent was signed by high US and Chinese officials, endorsing cooperative activities between the RERTR program and Chinese laboratories involved in similar activities. Joint studies of LEU technical feasibility were completed for the SAFARI-I reactor in South Africa and for the ANS reactor in the US. A new study has been initiated for the FRM-II reactor in Germany. Significant progress was made on several aspects of producing {sup 99}Mo from fission targets utilizing LEU instead of HEU. A cooperation agreements is in place with the Indonesian BATAN. The first prototypical irradiation of an LEU metal-foil target for {sup 99}Mo production was accomplished in Indonesia. The TR-2 reactor, in Turkey, began conversion. SAPHIR, in Switzerland, was shut down. LEU fuel fabrication has begun for the conversion of two more US reactors. Twelve foreign reactors and nine domestic reactors have been fully converted. Approximately 60 % of the work required to eliminate the use of HEU in US-supplied research reactors has been accomplished.« less

  19. Thermionic fast spectrum reactor-converter on the basis of multi-cell TFE

    NASA Astrophysics Data System (ADS)

    Ponomarev-Stepnoi, N. N.; Kompaniets, G. V.; Poliakov, D. N.; Stepennov, B. S.; Andreev, P. V.; Zhabotinsky, E. E.; Nikolaev, Yu. V.; Lapochkin, N. V.

    2001-02-01

    Today Russian experts have technological experience in development of in-core thermionic converters for reactors of space nuclear power plants. Such a converter contains nuclear fuel inside and really represents a fuel element of a reactor. Two types of reactors can be considered on the basis of these thermionic fuel elements: with thermal or intermediate neutron spectrum, and with fast neutron spectrum. The first type is characterized by the presence of moderator in core that ensures most economical usage of nuclear fuel. The estimation shows that moderated system is the most effective in the power range of about 5 ... 100 kWe. The power systems of higher level are characterized by larger dimensions due to the presence of moderator. The second type of reactor is considered for higher power levels. This power range is about hundreds kWe. Dimensions of the fast reactor and core configuration are determined by the necessity to ensure the required net output power, on the one hand, and the necessity to ensure critical state on the other hand. In the case of using in-core thermionic fuel elements of the specified design, minimal reactor output power is determined by reactor criticality condition, and maximum reactor power output is determined by specifications and launcher capabilities. In the present paper the effective multiplication factor of a fast spectrum reactor on the basis of a multi-cell TFE developed by ``Lutch'' is considered a function of the total number of TFEs in the reactor. The MCU Monte-Carlo code, developed in Russia (Alekseev, et al., 1991), was used for computations. TFE computational models are placed in the nodes of a uniform triangular lattice and surrounded with pressure vessel and a side reflector. Ordinary fuel pins without thermionic converters were used instead of some TFEs to optimize criticality parameters, dimensions and output power of the reactor. General weight parameters of the reactor are presented in the paper. .

  20. Management of fresh water weeds (macrophytes) by vermicomposting using Eisenia fetida.

    PubMed

    Najar, Ishtiyaq Ahmed; Khan, Anisa B

    2013-09-01

    In the present study, potential of Eisenia fetida to recycle the different types of fresh water weeds (macrophytes) used as substrate in different reactors (Azolla pinnata reactor, Trapa natans reactor, Ceratophyllum demersum reactor, free-floating macrophytes mixture reactor, and submerged macrophytes mixture reactor) during 2 months experiment is investigated. E. fetida showed significant variation in number and weight among the reactors and during the different fortnights (P <0.05) with maximum in A. pinnata reactor (number 343.3 ± 10.23 %; weight 98.62 ± 4.23 % ) and minimum in submerged macrophytes mixture reactor (number 105 ± 5.77 %; weight 41.07 ± 3.97 % ). ANOVA showed significant variation in cocoon production (F4 = 15.67, P <0.05) and mean body weight (F4 = 13.49, P <0.05) among different reactors whereas growth rate (F3 = 23.62, P <0.05) and relative growth rate (F3 = 4.91, P <0.05) exhibited significant variation during different fortnights. Reactors showed significant variation (P <0.05) in pH, Electrical conductivity (EC), Organic carbon (OC), Organic nitrogen (ON), and C/N ratio during different fortnights with increase in pH, EC, N, and K whereas decrease in OC and C/N ratio. Hierarchical cluster analysis grouped five substrates (weeds) into three clusters-poor vermicompost substrates, moderate vermicompost substrate, and excellent vermicompost substrate. Two principal components (PCs) have been identified by factor analysis with a cumulative variance of 90.43 %. PC1 accounts for 47.17 % of the total variance represents "reproduction factor" and PC2 explaining 43.26 % variance representing "growth factor." Thus, the nature of macrophyte affects the growth and reproduction pattern of E. fetida among the different reactors, further the addition of A. pinnata in other macrophytes reactors can improve their recycling by E. fetida.

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