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Sample records for mt blanc france

  1. A two century record of strontium isotopes from an ice core drilled at Mt Blanc, France

    NASA Astrophysics Data System (ADS)

    Burton, G. R.; Rosman, K. J. R.; Van de Velde, K. P.; Boutron, C. F.

    2006-08-01

    New techniques which allow small amounts of Sr to be reliably analysed [G.R. Burton, V.I. Morgan, C.F. Boutron, K.J.R. Rosman, High-sensitivity measurements of strontium isotopes in polar ice, Anal. Chim. Acta 469 (2002) 225-233] by TIMS (Thermal Ionisation Mass Spectrometry) have been used to measure the isotopic composition of Sr and the concentration of Rb and Sr at sub-nanogram per gram levels in a Mt Blanc snow and ice core. This two century time series of Sr isotopes is the first to be reported in an Alpine glacier. The Sr and Rb concentrations range from 3 ng/g to 20 pg/g and 1 ng/g to 10 pg/g, respectively, with higher concentrations evident in more recent times. This trend is consistent with that reported previously for other metals such as Cd, Cu and Zn [K. Van de Velde, C. Barbante, G. Cozzi, I. Moret, T. Bellomi, C. Ferrari, C. Boutron, Changes in the occurrence of silver, gold, platinum, palladium and rhodium in Mont Blanc ice and snow since the 18th century, Atmos. Environ. 34 (2000) 3117-3127; K. Van de Velde, C. Boutron, C. Ferrari, T. Bellomi, C. Barbante, S. Rudnev, M. Bolshov, Seasonal variations of heavy metals in the 1960s Alpine ice: sources versus meteorological factors, Earth Planet. Sci. Lett. 164 (1998) 521-533; K.J.R. Rosman, C. Ly, K. Van de Velde, C.F. Boutron, A two century record of lead isotopes in high altitude Alpine snow and ice, Earth Planet. Sci. Lett. 176 (2000) 413-424]. The 87Sr/ 86Sr ratios vary between 0.7020 and 0.7176 and display relatively larger variations in recent times which have been attributed to seasonal variations made evident by the increased sampling resolution available at shallower depths. No change with time is evident in this ratio which has a mean value of ˜ 0.712 and is similar to Glacial ice at Summit Greenland, suggesting that aerosols reaching Mt Blanc represent the same mixture of sources. Also, anthropogenic sources would appear to have the same isotopic ratio. The presence of Saharan dust in some

  2. Evolution of hut access facing glacier shrinkage in the Mer de Glace basin (Mont Blanc massif, France)

    NASA Astrophysics Data System (ADS)

    Mourey, Jacques; Ravanel, Ludovic

    2016-04-01

    Given the evolution of high mountain environment due to global warming, mountaineering routes and huts accesses are more and more strongly affected by glacial shrinkage and concomitant gravity processes, but almost no studies have been conducted on this relationship. The aim of this research is to describe and explain the evolution over the last century of the access to the five alpine huts around the Mer de Glace glacier (Mont Blanc massif), the larger French glacier (length = 11.5 km, area = 30 km²), a major place for Alpine tourism since 1741 and the birthplace of mountaineering, by using several methods (comparing photographs, surveying, collecting historical documents). While most of the 20th century shows no marked changes, loss of ice thickness and associated erosion of lateral moraines generate numerous and significant changes since the 1990s. Boulder falls, rockfalls and landslides are the main geomorphological processes that affect the access, while the glacier surface lowering makes access much longer and more unstable. The danger is then greatly increased and the access must be relocated and/or equipped more and more frequently (e.g. a total of 520 m of ladders has been added). This questions the future accessibility to the huts, jeopardizing an important part of mountaineering and its linked economy in the Mer de Glace area.

  3. Kinematics and thermal conditions in the permafrost-affected rockwalls of the Aiguille du Midi (3842 m a.s.l., Mont Blanc massif, France)

    NASA Astrophysics Data System (ADS)

    Ravanel, Ludovic; Grangier, Germain; Weber, Samuel; Beutel, Jan; Magnin, Florence; Gruber, Stefan; Deline, Philip

    2016-04-01

    Processes that control climate-dependent rockfall from permafrost-affected rock slopes are still poorly understood. In this study, we present the results of a Wireless Sensor Network, integrated within the Swiss project PermaSense and developed in 2012, to measure rock temperature and geotechnical parameters in the steep rockwalls of the Aiguille du Midi (AdM, 3842 m a.s.l., Mont Blanc massif, France). Accessible year round by cable car, the AdM comprises two main peaks: (i) the Piton Nord with the cable car arrival station, where 4 crack-meters are placed on four major fractures, and (ii) the Piton Central with many touristic infrastructure, equipped with three 10-m-deep boreholes with 15 temperatures sensors since 2009, and where 2 crack-meters are installed along a major fracture. Three major kinematic regimes are observed: (i) opening of clefts when the rock temperature becomes positive, followed by closing during the cold period, (ii) summer opening continued by a winter opening, and (iii) closing during the warm period followed by opening in winter.

  4. GPS and TerraSAR-X time series measure temperate glacier flow in the Mont Blanc massif (France): the Argentière glacier test site.

    NASA Astrophysics Data System (ADS)

    Ponton, F.; Walpersdorf, A.; Gay, M.; Trouvé, E.; Mugnier, J. L.; Fallourd, R.; Cotte, N.; Ott, L.; Serafini, J.

    2012-04-01

    We present measurements of the surface velocity of the Argentière glacier in the Mont Blanc massif, France, obtained by SAR and GPS observations. We produce surface velocity fields from several couples of descending and ascending TerraSAR-X acquisitions repeated at 11 days intervals in spring 2009, using the offset power tracking technique. Moreover, we dispose of four years of GPS data acquired continuously on the Argentière glacier. Our local permanent GPS network is composed of two stations on the glacier at altitudes of 2441 m and 2770 m, and two stations in static places, one in the valley of Chamonix at an altitude of 1121 m and the other on a rock outcrop near the glacier at the altitude of 2835 m. The measurements yield average displacement rates of about 13 cm/day for the upper glacier station (2770 m) and 17 cm/day for the lower site (2441 m). These in situ GPS results have been used already to validate the displacement rates of a corner reflector on the glacier measured by SAR interferometry. Here, we will use the GPS observations to validate longitudinal profiles of the surface velocity field obtained by offset power tracking. The combination of continuous GPS time series and successive TerraSAR-X images yield new information on temperate glacier dynamics, constraining an annual variability of the displacement rates of up to 28 %, with fastest flow in late summer, and a spatial variability of the displacement rates of up to 50%, with fastest flow at the bottom of the glacier. The continuous monitoring (in space and time) of the Argentière glacier flow over several annual cycles can be used to examine the correlation with climatological parameters such as temperature and cumulated precipitations and provides an exceptional data set for improving models of temperate glacier flow mechanisms.

  5. Basal icequakes recorded beneath an Alpine glacier (Glacier d'Argentière, Mont Blanc, France): Evidence for stick-slip motion?

    NASA Astrophysics Data System (ADS)

    Helmstetter, Agnès.; Nicolas, Barbara; Comon, Pierre; Gay, Michel

    2015-03-01

    While basal icequakes associated with glacier motion have been detected under Antarctica for several decades, there remains very little evidence of stick-slip motion for Alpine glaciers. Here we analyzed 2357 basal icequakes that were recorded at Glacier d'Argentière (Mont-Blanc Massif) between February and November of 2012 and that are likely to be associated with basal sliding. These events have been classified into 18 multiplets, based on their waveforms. The strong similarity of the waveforms within each multiplet suggests an isolated repeating source. Despite this similarity, the peak amplitude within each multiplet varies gradually in time, by up to a factor of 18. The distribution of these events in time is relatively complex. For long time scales, we observe progressive variations in the amplitudes of events within each multiplet. For intermediate time scales (hours), the events occur regularly in time, with typical return times of several minutes up to several hours. For short time scales (from 0.01 to 100 s), the largest multiplet shows clustering in time, with a power law distribution of the interevent times. The location of these events and their focal mechanisms are not well constrained, because most of these events were detected by a single seismometer. Nevertheless, the locations can be estimated with an accuracy of a few tens of meters using a polarization analysis. The estimated average depth of the basal events is 179 m, which is in good agreement with the estimated glacier thickness. The relative changes in distance between the source and the sensor can be measured accurately by correlating separately the P wave and S wave parts of the seismograms of each event with the template waveforms, which are obtained by averaging the signals within each multiplet. We observed small variations in the times between the P wave and the S wave of up to 0.6 ms over 50 days. These variations cannot be explained by displacement of the sensor with respect to the

  6. Surface-to-base transfer and subglacial hydrology controls on subglacial erosion evidenced from 7 years of hydro-sedimentary observations within Bossons glacier catchment (Mont-Blanc massif, France)

    NASA Astrophysics Data System (ADS)

    Guillon, Hervé; Mugnier, Jean-Louis; Buoncristiani, Jean-François

    2016-04-01

    Continuous monitoring of sediment load in proglacial rivers allows to quantify the mass of sediment exported from a glaciated catchment toward the fluvial system. However, supraglacial, subglacial and proglacial sources contribute to this export and their specific roles are poorly understood. Our general intent in this study is to understand their respective contribution to the total exported load of suspended sediment. The catchment of the rapidly retreating Bossons glacier (Mont-Blanc massif, France) provides an ideal field laboratory to infer about the intensity of present-day erosion processes. On this glacier, two proglacial rivers were monitored : Crosette stream and Bossons stream. For Bossons stream, completing the initial 2009-2010 data, discharge and sediment load have been measured from 2011 to 2015 at a high time resolution (timestep from 15 to 2 min). Two stations acquired these data, upstream and downstream, respectively, from a valley sandur located at ˜1 km from the glacial tongue. Crosette stream was monitored directly at the exit of the subglacial system during 2013 and 2014. The combined dataset currently available from these 3 stations spans 7 years from 2009 to 2015, is not only limited to the melt season duration and is appreciably rich (4.3 millions raw data points). This tremendous data profusion allowed developping statistical methods. Multi-linear models were used to investigate sediment transfer processes in the proglacial area during the 2013 melt season. An original probabilistic approach provided critical information for every other years. Uncertainties on sediment masses were assessed by a careful propagation and by a Monte-Carlo method. Additionnaly, sediment transfer from supraglacial to subglacial position has been estimated for Crosette and Bossons streams. Applying the conclusions of these previous works on the 7 years dataset, we provide erosion rates for the supraglacial rockwalls, subglacial bedrock and proglacial area

  7. Multi-stage melt-rock interaction in the Mt. Maggiore (Corsica, France) ophiolitic peridotites: microstructural and geochemical evidence

    NASA Astrophysics Data System (ADS)

    Rampone, Elisabetta; Piccardo, Giovanni B.; Hofmann, Albrecht W.

    2008-10-01

    Spinel and plagioclase peridotites from the Mt.Maggiore (Corsica, France) ophiolitic massif record a composite asthenosphere-lithosphere history of partial melting and subsequent multi-stage melt-rock interaction. Cpx-poor spinel lherzolites are consistent with mantle residues after low-degree fractional melting ( F = 5-10%). Opx + spinel symplectites at the rims of orthopyroxene porphyroclasts indicate post-melting lithospheric cooling ( T = 970-1,100°C); this was followed by formation of olivine embayments within pyroxene porphyroclasts by melt-rock interaction. Enrichment in modal olivine (up to 85 wt%) at constant bulk Mg values, and variable absolute REE contents (at constant LREE/HREE) indicate olivine precipitation and pyroxene dissolution during reactive porous melt flow. This stage occurred at spinel-facies depths, after incorporation of the peridotites in the thermal lithosphere. Plagioclase-enriched peridotites show melt impregnation microtextures, like opx + plag intergrowths replacing exsolved cpx porphyroclasts and interstitial gabbronoritic veinlets. This second melt-rock interaction stage caused systematic chemical changes in clinopyroxene (e.g. Ti, REE, Zr, Y increase), related to the concomitant effects of local melt-rock interaction at decreasing melt mass, and crystallization of small (<3%) trapped melt fractions. LREE depletion in minerals of the gabbronoritic veinlets indicates that the impregnating melts were more depleted than normal MORB. Preserved microtextural evidence of previous melt-rock interaction in the impregnated peridotites suggests that they were progressively uplifted in response to lithosphere extension and thinning. Migrating melts were likely produced by mantle upwelling and melting related to extension; they were modified from olivine-saturated to opx-saturated compositions, and caused different styles of melt-rock interaction (reactive spinel harzburgites, vs. impregnated plagioclase peridotites) depending on the

  8. France.

    PubMed

    1993-02-10

    Taxes on cigarettes in France have been increased by 15 per cent, the first of an overall rise of 30 per cent. Part of the revenue raised will help subsidise motor racing which lost its sponsors following a recent national ban on cigarette advertising. The remainder will go to the social security service.

  9. France

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Every July, the world's best cyclists race more than 3500 km around France, and sometimes the surrounding countries, in the Tour de France. This image from the Moderate resolution Imaging Spectroradiometer (MODIS) shows the varied terrain which challenges the riders. The race started in western France at Futuroscope, and headed toward Brittany. In these mostly flat 'stages' (as each day's race is called) sprinting specialists usually dash for the finish out of the main pack of riders. The race then moved to the Pyrenees mountains, in southern France along the border with Spain. Climbers and the overall favorites shine in the mountains, often gaining 10 minutes or more on their rivals. Only a few days after the Pyrenees climbs the race was again in the mountains. First Mont Ventoux, an extinct volcano in Provence, and then the massive Alps, with altitudes as high as 2,645 meters, challenged the racers. Finally the race headed toward Paris and a July 23rd finish in Paris. Go Lance! To learn more about MODIS, visit the MODIS web. Image by Jacques Descloitres, MODIS Land group, NASA GSFC

  10. France.

    PubMed

    1987-09-01

    In 1986, France had a population of 55,493,000, with an annual growth rate of 0.4%. The infant mortality rate stood at 8.2/1000. Of the work force of 23.8 million, 8.3% were engaged in agriculture, 45.2% were in the industry and commerce sector, and 46.5% were engaged in services. The unemployment rate stood at 10.7%. The country's gross domestic product (GDP) was US$724 billion in 1986, with an average annual growth rate of 2.0%, and per capita income averaged $13,046. France has substantial agricultural resources, a diversified modern industrial system, and a highly skilled labor force. Following the return of a socialist majority in government in 1981, several large manufacturing firms were nationalized along with much of the commercial banking sector. Initial socialist policies were stimulative, relying partly on income redistribution and partly on increased government spending. However, the resultant increase in import demand was not offset by an increased demand French exports. In 1983, an economic stabilization plan of reductions in the budget deficit, involving spending cuts, increased taxes, and tighter monetary and credit policies, was successfully implemented. Although current economic policies should promote stronger growth over the medium to long term, trade competitiveness remains weak and high unemployment is a major social problem.

  11. Contained events in the Mont-Blanc nucleon stability experiment

    NASA Astrophysics Data System (ADS)

    Battistoni, G.; Campana, P.; Chiarella, V.; Ciocio, A.; Iarocci, E.

    1986-04-01

    The nucleon-stability experiment (NUSEX) underway at Mt. Blanc Laboratory is briefly described, and some preliminary results are reported. NUSEX is designed to both generate nucleons and detect eventual nucleon decays, and comprises 136 1-cm-thick iron sheets interleaved with limited streamer tubes and arranged in a 3.5-m cube; the active mass for nucleon decay is about 130 tons. During 22,350 h of live time (equivalent to 2.3 x 10 to the 32nd nucleon yr) up to April 1985, 30 contained events were recorded (22 attributed to numu and seven attributed to nue), corresponding to a neutrino interaction rate of 149 + or - 27/kton yr.

  12. The Mont Blanc detection of neutrinos from SN 1987A.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Kalchukov, F. F.; Kortchaguin, V. B.; Kortchaguin, P. V.; Malguin, A. S.; Ryassny, V. G.; Ryazhkaya, O. G.; Saavedra, O.; Talochkin, V. P.; Trinchero, G.; Vernetto, S.; Zatsepin, G. T.; Yakushev, V. F.

    The authors discuss the event detected in the Mont Blanc Underground Neutrino Observatory on February 23, 1987, during the occurrence of supernova SN 1987A. The pulse amplitudes, the background imitation probability, and the energetics connected with the event are reported. It is also shown that some interactions recorded at the same time in other underground experiments, with a lower detection efficiency, are consistent with the Mont Blanc event.

  13. Results of the liquid scintillation detector of the Mont Blanc Laboratory

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G. F.; Castagnoli, C.; Fulgione, W.

    1986-04-01

    Preliminary results research on collapsing-star neutrino bursts and cosmic-ray muons, obtained using the 90-ton 72 element liquid-scintillation detector (LSD) at Mt. Blanc Laboratory since October 1984, are presented in tables and graphs and characterized. The theoretically expected energy and time values for neutrinos from collapsing stars of 2 solar mass are calculated, and it is shown that no burst with multiplicity 6 or greater and Delta t 30 s or less was detected in 4 mo of LSD live time, corresponding to a preliminary upper limit of 3/yr for Galactic stellar collapses. About 3 muons/h crossing at least two counters were observed, and detection of aobut 700 muon bundles per year of multiplicity 2 or greater or 90 bundles per year of multiplicity 3 or greater is predicted. The possible use of the LSD to search for nucleon instability (proton decay into muons) is considered.

  14. Wind-driven surface circulation in the Cape Blanc region

    NASA Astrophysics Data System (ADS)

    Castellanos, P.; Pelegrí, J. L.; Benazzouz, A.

    2013-06-01

    We analyze the short-term transition, on time scales of the order of days and weeks, of the surface fields in the coastal transition zone off Northwest Africa, between 15°N and 25°N, during winter and spring 2005 and 2006. This is a complex region characterized by the baroclinic coastal jet north of Cape Blanc, along-shore convergence and water export at the Cape Blanc giant filament, and substantial mesoscale variability between Capes Verde and Blanc. We use the anomalies of the wind impulse and two different coastal upwelling indexes, evaluated off 17°N, 20°N and 23°N, in order to assess the importance of wind forcing in this short-term variability. We also employ daily and weekly surface maps of wind, temperature, surface height and currents to investigate which are the mechanisms that lead to the relatively fast changes in the flow patterns. The coastal baroclinic jet and the Cape Blanc giant filament are ubiquitous features, the two being intrinsically related through the intensity of upwelling off Cape Blanc. Therefore, the strength of both features responds, to a large extent, to the fluctuations of the northeasterly winds; their intensity is greater in spring than winter but during both seasons they experience relatively fast oscillations related to the intermittency of the wind field. The mesoscalar features are visible in the entire domain, with time scales typically of the order of two weeks, but become prominent in the southern region during spring, apparently related to an intense northward coastal jet south of Cape Blanc.

  15. Mise en évidence de déformations en faille inverse avec ruptures de surface cosismiques dans des dépôts colluviaux würmiens du versant nord du mont Ventoux (Provence occidentale, France)Evidence of reverse faulting and coseismic surface ruptures in Würm colluvial deposits from the Mt Ventoux northern slope (Western Provence, France)

    NASA Astrophysics Data System (ADS)

    Dutour, Alain; Philip, Hervé; Jaurand, Erwan; Combes, Philippe

    In western Provence (France), brittle deformation of Quaternary age occurring in the vicinity of the Nı̂mes and Durance faults has been linked to palaeoseisms of significant magnitude. Our new observations made on the southern rim of the Tertiary Malaucène Basin, in the continuation of a thrust to the north of Mt Ventoux, present evidence for reverse faulting deformation in deposits of a Würm colluvial fan. The analysis of a trench section provides clear evidence for: (1) the development of two successive surface ruptures and degradation of associated scarps during the Mid-Upper Würm, and, (2) the continuation of the reverse fault within the Oligocene basement. These tectonic events were associated with earthquakes of at least 6 in magnitude. To cite this article: A. Dutour et al., C. R. Geoscience 334 (2002) 849-856.

  16. Neutrino astronomy at Mont Blanc: from LSD to LSD-2.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Kalchukov, F. F.; Kortchaguin, V. B.; Kortchaguin, P. V.; Malguin, A. S.; Ryassny, V. G.; Ryazskaya, O. G.; Saavedra, O.; Talockin, V. P.; Trinchero, G.; Vernetto, S.; Zatsepin, G. T.; Yakushev, V. F.

    In this paper the authors present the upgrading of the LSD experiment, presently running in the Mont Blanc Laboratory. The data recorded during the period when supernova 1987A exploded are analysed in detail. The research program of LSD-2, the same experiment as LSD but with a higher sensitivity to search for neutrino bursts from collapsing stars, is also discussed.

  17. Search for neutrinos from collapsing stars at Mont Blanc.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Kalchukov, F. F.; Kortchaguin, V. B.; Kortchaguin, P. V.; Malguin, A. S.; Ryassny, V. G.; Ryazskaya, O. G.; Saavedra, O.; Talockin, V. P.; Trinchero, G.; Vernetto, S.; Zatsepin, G. T.; Yakushev, V. F.

    The authors present the upgrading of the LSD experiment, presently running in the Mont Blanc Laboratory. The data recorded during the period when supernova 1987A exploded are analysed in detail. The research program of LSD-2, the same experiment as LSD but with an higher sensitivity to search for neutrino bursts from collapsing stars, is also discussed.

  18. The Mont Blanc detector of neutrinos from collapsing stars.

    NASA Astrophysics Data System (ADS)

    Saavedra, O.

    The author describes the upgrading of the LSD experiment presently running in the Mont Blanc Laboratory, and the research program of LSD-2, the same experiment as LSD but with a higher sensitivity to search for neutrino bursts from collapsing stars.

  19. The neutrino burst from SN 1987A detected in the Mont Blanc LSD experiment.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Kalchukov, F. F.; Khalchukov, F. F.; Kortchaguin, V. B.; Korchagin, V. B.; Kortchaguin, P. V.; Korchagin, P. V.; Malguin, A. S.; Mal'Gin, A. S.; Ryassny, V. G.; Ryasnyj, V. G.; Ryazhkaya, O. G.; Saavedra, O.; Talochkin, V. P.; Trinchero, G.; Vernetto, S.; Zatsepin, G. T.; Yakushev, V. F.

    The authors discuss the event, (5 interactions recorded during 7 seconds) detected in the Mont Blanc Underground Neutrino Observatory on February 23, 1987, during the occurrence of supernova SN 1987A. The pulse amplitudes, the background imitation probability, and the energetics connected with the event are reported. It is also shown that some interactions recorded at the same time in other underground experiments, with a lower detection efficiency, are consistent with the Mont Blanc event.

  20. Dental abnormalities in the osteopetrotic rat mutation microphthalmia blanc.

    PubMed

    Cielinski, M J; Iizuka, T; Marks, S C

    1994-11-01

    Dental manifestations of the mild, transient osteopetrosis in the rat mutation microphthalmia blanc (mib) were examined. Eruption of all teeth was delayed in mib rats compared to normal littermates. The delays ranged from 5 days for incisors to 3 and 2 days for the first and second molars. Normal rats had straight incisors in the sagittal plane that exhibited signs of wear, but in mib littermates the incisors were maloccluded, distorted, and showed no signs of wear. Radiographic and histological examination of the dentition of 1- and 4-week-old rats revealed that the apical end of incisors in mib rats failed to extend posteriorly to the third molar region as in normal siblings, but ended at the first molar. Histological examination of longitudinal sections of mandibles through the incisors of neonatal normal and mib rats showed that in 1-day-old mutants the incisor was closely surrounded by alveolar bone to which it was ankylosed. The incisor body in mib rats was also malformed, with an indented apical end. This ankylosis was temporary, being resolved by 3 days. These findings show that neonatal reductions in bone resorption cause incisor defects and delay the eruption of all teeth in mib rats. The malocclusion and distortion of incisors of mib rats are likely caused by temporary ankylosis of incisor matrices to alveolar bone. Taken together, these findings illustrate the concept that bone resorption is an essential and rate-limiting element of tooth eruption.

  1. Monitoring the morphological evolution of complex glaciers: the Planpincieux case-study (Mont Blanc - Aosta Valley)

    NASA Astrophysics Data System (ADS)

    Giordan, Daniele; Manconi, Andrea; Allasia, Paolo; Curtaz, Michèle; Vagliasindi, Marco; Bertolo, Davide

    2014-05-01

    The Planpincieux Glacier (PG) is located on the Italian side of the Grandes Jorasses massif, Mont Blanc, Italy. This area is historically known for the occasional activation of ice falls events from the frontal part of the glacier. The PG is a so-called "polythermal" glacier, meaning that the liquid water present at contact between ice and the bedrock in the lower part of the glacier itself plays an important role in the glacier dynamics, and ice falls might occur in a sudden and unpredictable fashion. In this scenario, the accurate analysis of the glacier morphological evolution assumes a crucial role. Starting from 2012, within the framework of the regional plan for glaciers risk detection, a research project was set up to study the Planpincieux Glacier and evaluate the potential hazard concerning the possible activation of large ice or ice-snow avalanches triggered by icefall events in that area. Dynamics of such avalanches, as well as potentially endangered areas, have been evaluated in an expertise by the SLF Institute. Therefore, the availability of both qualitative information and quantitative measurements relevant to the glacier movements represented a primary goal. After a careful evaluation of several possible technical solutions to achieve displacement monitoring also based on the results of a preliminary study managed by the ETH Zurich (prof. M. Funk), we installed an experimental monitoring station located on the opposite side of the valley, at the top of the Mt. de la Saxe, ca. 3.5 km away from the main target. The monitoring station is composed of two modules, including: (i) a surveillance module, based on a medium resolution digital camera, observing large part of the slope; (ii) a photogrammetric module, based on a high resolution digital camera equipped with a 300mm optical zoom, pointed on the Planpincieux glacier front. At this stage, our analyses focused mainly on the qualitative assessment and recognition of impulsive phenomena affecting the

  2. Microbiological fingerprint of African dust deposition in alpine snow pack, Mont Blanc summit

    NASA Astrophysics Data System (ADS)

    Chuvochina, Maria; Alekhina, Irina; Normand, Philippe; Petit, Jean-Robert; Bulat, Sergey

    2010-05-01

    The biogeochemical effect of African dust transport has been reported mostly with respect to nutrient budget change in both terrestrial and aquatic ecosystems and global transport of microorganisms, including pathogens. However, its potential to seed or colonize the remote environments by transported microorganisms is poorly understood. This study has focused on bacterial content and diversity of Saharan dust deposition from 2006, 2008 and 2009 in snow pack of Mont Blanc (MtBl) glacier as well as recognition of bacteria which could be involved in establishing microbiota in this icy environment. Four snow samples recorded Saharan dust events from June 2006 (SDm06/2006 - 3,5 months aged), May and June 2008 (SDm05/2008 and SDm06/2008 - 1 month in between and 1 week aged each) and May 2009 (SDm05/2009 - 1 week aged) were collected at Col du Dome area (4250m a.s.l.). Bacterial community structure was assessed by ribotyping and subsequent sequencing of bacterial 16S rRNA genes. To exclude human-associated and laboratory contamination several controls were run in parallel updating our contaminant library. The obtained phylotypes were tested against this library keeping only those which successfully passed through this exam. Of 176 selected clones from four clone libraries 29.8% were met in our contaminant library. The ‘true' sequences were assigned to 57 phylotypes (>97.5% sequence similarity) originating mostly from soil. The prevalent phylotypes recovered were belonging to different bacterial divisions: Deinococcus-Thermus, Alpha-proteobacteria and CFB groups for SDm06/2006; Actinobacteria, Alpha-proteobacteria and CFB for SDm05/2008 and SDm06/2008; Actinobacteria and chloroplasts/plastids for SDm05/2009. Phylogenetic analysis of all phylotypes showed no shared species amongst all 4 dust layers in MtBl snow pack in 2006, 2008 and 2009. However, two phylotypes (Blastococcus saxobsidens sp. - 99%, Geodermatophilus obscurus sp. - 99%) were shared between 2008 and 2009

  3. Large solar flares - Analysis of the events recorded by the Mont Blanc neutrino detector

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Kalchukov, F. F.; Korolkova, I. V.; Kortchaguin, P. V.; Kudryavtsev, V. A.; Malguin, A. S.; Periale, L.; Ryassny, V. G.; Ryazhskaya, O. G.; Saavedra, O.; Trinchero, G.; Vernetto, S.; Yakushev, V. F.; Zatsepin, G. T.

    1991-11-01

    Analytical results are discussed from events recorded by the Mont Blanc neutrino detector during 19 large solar flares from August 1988 to March 1990, including the powerful flares of September 29 and October 19, 1989. It is found that no significant neutrino signal coincides temporally with solar flares. Upper limits are obtained for the integral neutrino and antineutrino flux of different flavors.

  4. The PermaFRANCE network

    NASA Astrophysics Data System (ADS)

    Schoeneich, Philippe

    2010-05-01

    A French long term monitoring network of permafrost and frost related processes, named PermaFRANCE, is being built since two years. It will represent the French contribution to the Alpine wide PermaNET network. The PermaFRANCE network will focus not only on permafrost, but on all frost related phenomena at different altitudinal levels, including both thermal monitoring and process observation and monitoring : 1) continuous and discontinuous permafrost in rock walls : - thermal monitoring is mainly performed at the Aiguille du Midi (Mont Blanc massif) and includes rock surface temperature (RST) and temperature profils in medium depth boreholes (10 m) ; - inventory and observation of rockfall activity in high mountain rock walls : this action concerns the whole Mont Blanc area and is based on a hitorical inventory and an observation of current activity based on a network of observers and contributors ; 2) discontinuous permafrost is surficial deposits and flat bedrock : - thermal monitoring is performed on five rockglacier sites and includes ground surface temperature (GST) and annual BTS campaigns on some sites. Two medium depth boreholes (15 m) have been made in 2009 on one site, and equipped for thermal profile monitoring. A deep borehole (100 m) will be made in 2010 at 45° N latitude ; - geophysical monitoring is performed on 4 sites : repeated vertical electrical soundings exist for some sites since 20 years, and have been complemented since 2007 by eletrical resistivity tomography (ERT) and refraction seismics ; - surficial displacements of rockglaciers : surficial displacements are measured either by classical geodesy or by DGPS on 6 rockglaciers ; 3) sporadic permafrost at middle altitudes : - an inventory of cold scree slopes and biological investigations on soil and tree growth (dendrogeomorphology) have already been achieved ; - a thermal monitoring should be initiated on selected sites in 2010 ; 4) seasonal frost and frost/thaw cycles at middle and low

  5. Microbial communities established on Mont Blanc summit with Saharan dust deposition

    NASA Astrophysics Data System (ADS)

    Chuvochina, M.; Alekhina, I.; Normand, P.; Petit, J. R.; Bulat, S.

    2009-04-01

    Dust originating from the Sahara desert can be uplifted during storms, transported across the Mediterranean towards the Alpine region and deposited during snowfalls. The microbes associated with dust particles can be involved in establishing microbiota in icy environments as well as affect ecosystem and human health. Our objective was to use a culture-free DNA-based approach to assess bacterial content and diversity and furthermore, to identify ‘icy' microbes which could be brought on the Mont Blanc (MtBl) summit with Saharan dust and became living in the snow. Saharan dust fallout on MtBl summit from one event (MB5, event June 2006) vs. control libraries and that from another event (May 2008) were collected in Grenoble (SD, 200 m a.s.l.) and at Col du Dome (MB-SD, 4250 m a.s.l.). Soil from Ksar Ghilane (SS, Saharan desert, Tunisia, March 2008) was taken for overall comparison as a possible source population. Fresh snow falling in Grenoble (85) was collected as example of diversity in this area. To assess the microbial diversity 16S rRNA gene libraries (v3-v5 region) were constructed for corresponding dust-snow samples (MB5, SS, SD, 85 and MB-SD) along with clear snow samples and several controls. For both MB5 and MB-SD samples full-gene technique was evoked in attempt to differentiate reproduced bacteria from damaged DNA. Before sequencing the clones were rybotyped. All clone libraries were distinct in community composition except for some single phylotypes (or closely related groups) overlap. Thus, clone libraries from two different events that were collected at Col du Dome area within 2 year interval (MB5 and MB-SD) were different in community composition except one of the abundant phylotype from MB-SD library (Geodermatophilus sp.) which was shared (98% sequence similarity) with single representative from MB-5 library. These bacteria are pigmented and radiation-resistant, so it could be an indicator of desert origin for our sequences. For MB5 library two

  6. Monitoring surface displacements of glaciers with ground based photogrammetry: insights from Planpincieux Glacier, Grandes Jorasses massif, Mont Blanc

    NASA Astrophysics Data System (ADS)

    Manconi, Andrea; Dell'Anese, Federico; Giordan, Daniele; Allasia, Paolo; Curtaz, Michèle; Vagliasindi, Marco; Bertolo, Davide

    2015-04-01

    Monitoring the spatial and temporal evolution of glaciers modifications in a climate change scenario is a major scientific problem. The Italian side of the Grandes Jorasses massif, Mont Blanc, is historically known for the occasional activation of icefalls events from the frontal part of the glaciers located on that area. The Planpincieux Glacier (PG) is a "polythermal" glacier, meaning that the liquid water present at the contact between ice and the bedrock in the lower part of the glacier itself plays an important role in its dynamics. Under these conditions icefalls might occur in a sudden and barely predictable manner. In this scenario, an accurate analysis of its morphological evolution is crucial; however, one of the major problems on PG is the limited access to perform direct measurements. For this reason, remote sensing has been identified as the more convenient approach to achieve quantitative measurements of surficial modifications. An experimental monitoring station was installed on August 2013 in order to monitor the surface displacements at PG. The monitoring station is located on the opposite side of the valley, at the top of the Mt. de la Saxe, ca. 3.5 km away from the target under investigation. Monitoring includes: (i) a surveillance module, based on a medium resolution digital camera, observing large part of the slope; (ii) a photogrammetric module, based on a high resolution digital camera equipped with a 300 mm optical zoom, pointed to the PG front. Digital images acquired by the monitoring station are acquired with a revisit time of 1-hour, and analyzed by considering change-detection and pixel-offset techniques. This approach allows to evaluate surface changes over time, as well as to retrieve quantitative measurements of the glacier displacements. Here we present the results after one year of monitoring, and we discuss how the combination of different remote sensing techniques can be exploited for a better understanding of the glacier

  7. Coincidences among Mont Blanc, Kamiokande, Baksan, IMB, Frejus, Homestake and Plateau Rosa detectors during SN1987A.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Fulgione, W.; Galeotti, P.; Saavedra, O.; Trinchero, G.; Vernetto, S.

    Correlation analysis has been performed among the events recorded during the occurrence of SN1987A by the underground detectors of Mont Blanc, Kamiokande, Baksan, IMB, Frejus, Homestake and the EAS array of Plateau Rosa. A significative excess of coincidence exists between low energy events of Mont Blanc and IMB muons, in the time interval from 1:45 to 3:45 UT on Feb. 23, 1987.

  8. Drug Use on Mont Blanc: A Study Using Automated Urine Collection

    PubMed Central

    Robach, Paul; Trebes, Gilles; Lasne, Françoise; Buisson, Corinne; Méchin, Nathalie; Mazzarino, Monica; de la Torre, Xavier; Roustit, Matthieu; Kérivel, Patricia; Botré, Francesco; Bouzat, Pierre

    2016-01-01

    Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological capacities. This practice may be unsafe in this remote alpine environment. However, robust data on medication during the ascent of Mont Blanc are lacking. Individual urine samples from male climbers using urinals in mountain refuges on access routes to Mont Blanc (Goûter and Cosmiques mountain huts) were blindly and anonymously collected using a hidden automatic sampler. Urine samples were screened for a wide range of drugs, including diuretics, glucocorticoids, stimulants, hypnotics and phosphodiesterase 5 (PDE-5) inhibitors. Out of 430 samples analyzed from both huts, 35.8% contained at least one drug. Diuretics (22.7%) and hypnotics (12.9%) were the most frequently detected drugs, while glucocorticoids (3.5%) and stimulants (3.1%) were less commonly detected. None of the samples contained PDE-5 inhibitors. Two substances were predominant: the diuretic acetazolamide (20.6%) and the hypnotic zolpidem (8.4%). Thirty three samples were found positive for at least two substances, the most frequent combination being acetazolamide and a hypnotic (2.1%). Based on a novel sampling technique, we demonstrate that about one third of the urine samples collected from a random sample of male climbers contained one or several drugs, suggesting frequent drug use amongst climbers ascending Mont Blanc. Our data suggest that medication primarily aims at mitigating the symptoms of altitude illnesses, rather than enhancing performance. In this hazardous environment, the relatively high prevalence of hypnotics must be highlighted, since these molecules may alter vigilance. PMID:27253728

  9. The research program of the Liquid Scintillation Detector (LSD) in the Mont Blanc Laboratory

    NASA Technical Reports Server (NTRS)

    Dadykin, V. L.; Yakushev, V. F.; Korchagin, P. V.; Korchagin, V. B.; Malgin, A. S.; Ryassny, F. G.; Ryazhskaya, O. G.; Talochkin, V. P.; Zatsepin, G. T.; Badino, G.

    1985-01-01

    A massive (90 tons) liquid scintillation detector (LSD) has been running since October 1984 in the Mont Blanc Laboratory at a depth of 5,200 hg/sq cm of standard rock. The research program of the experiment covers a variety of topics in particle physics and astrophysics. The performance of the detector, the main fields of research are presented and the preliminary results are discussed.

  10. Drug Use on Mont Blanc: A Study Using Automated Urine Collection.

    PubMed

    Robach, Paul; Trebes, Gilles; Lasne, Françoise; Buisson, Corinne; Méchin, Nathalie; Mazzarino, Monica; de la Torre, Xavier; Roustit, Matthieu; Kérivel, Patricia; Botré, Francesco; Bouzat, Pierre

    2016-01-01

    Mont Blanc, the summit of Western Europe, is a popular but demanding high-altitude ascent. Drug use is thought to be widespread among climbers attempting this summit, not only to prevent altitude illnesses, but also to boost physical and/or psychological capacities. This practice may be unsafe in this remote alpine environment. However, robust data on medication during the ascent of Mont Blanc are lacking. Individual urine samples from male climbers using urinals in mountain refuges on access routes to Mont Blanc (Goûter and Cosmiques mountain huts) were blindly and anonymously collected using a hidden automatic sampler. Urine samples were screened for a wide range of drugs, including diuretics, glucocorticoids, stimulants, hypnotics and phosphodiesterase 5 (PDE-5) inhibitors. Out of 430 samples analyzed from both huts, 35.8% contained at least one drug. Diuretics (22.7%) and hypnotics (12.9%) were the most frequently detected drugs, while glucocorticoids (3.5%) and stimulants (3.1%) were less commonly detected. None of the samples contained PDE-5 inhibitors. Two substances were predominant: the diuretic acetazolamide (20.6%) and the hypnotic zolpidem (8.4%). Thirty three samples were found positive for at least two substances, the most frequent combination being acetazolamide and a hypnotic (2.1%). Based on a novel sampling technique, we demonstrate that about one third of the urine samples collected from a random sample of male climbers contained one or several drugs, suggesting frequent drug use amongst climbers ascending Mont Blanc. Our data suggest that medication primarily aims at mitigating the symptoms of altitude illnesses, rather than enhancing performance. In this hazardous environment, the relatively high prevalence of hypnotics must be highlighted, since these molecules may alter vigilance.

  11. An event observed by the Mont Blanc underground neutrino detector on February 23, 1987

    NASA Astrophysics Data System (ADS)

    Dadykin, V. L.; Zatsepin, G. T.; Korchaguin, V. B.; Korchaguin, P. V.; Malgin, A. S.; Ryazhskaya, O. G.; Ryassny, V. G.; Talochkin, V. P.; Khalchukov, F. F.; Yakushev, V. F.; Aglietta, M.; Badino, G.; Bologna, G.; Vernetto, S.; Galeotti, P.; Castagnoli, C.; Castellina, A.; Saavedra, O.; Trinchero, G.; Fulgione, W.

    1988-02-01

    An analysis is made of the event detected by the Soviet-Italian neutrino scintillation detector (LSD) beneath Mont Blanc on Februrary 23, 1987 at 2:52:37 UT. Corrected energies of the pulses of the event have been determined along with the probability of event imitiation by the background. The LSD data are compared with Kamiokande and IMB data. The possibility that the observed event may be connected with the explosion of SN 1987A is examined.

  12. Analysis of the data recorded by the Mont Blanc neutrino detector andby the Maryland and Rome gravitational wave detectors during SN1987A.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Amaldi, E.; Badino, G.; Bassan, M.; Bologna, G.; Bonifazi, P.; Castagnoli, C.; Castellano, M. G.; Castellina, A.; Coccia, E.; Cosmelli, C.; Dadykin, V. L.; Frasca, S.; Fulgione, W.; Galeotti, P.; Gretz, D.; Kalchukov, F. F.; Malguin, A. S.; Modena, I.; Pallottino, G. V.; Pizzella, G.; Rapagnani, P.; Ricci, F.; Ryassny, V. G.; Ryazhskaya, O. G.; Saavedra, O.; Trinchero, G.; Vannaroni, G.; Vernetto, S.; Weber, J.; Wilmot, G.; Zatsepin, G. T.

    The data recorded by the gravitational wave and neutrino detectors have been analyzed over a period of 18h that includes the Mont Blanc 5ν burst occurrence time. A correlation is found during a period of about two hours roughly centered on the 5ν burst, independently between Maryland and Mont Blanc and Rome and Mont Blanc. The probability that these two correlations be due to chance is of the order of 3×10-6.

  13. Analysis of the data recorded by the Mont Blanc neutrino detector and by the Maryland and Rome gravitational-wave detectors during SN 1987 A

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.

    1989-02-01

    The paper presents data recorded by the neutrino detector on Mont Blanc and by gravitational wave detectors in Maryland and Rome. The data were obtained over a period of several days and include the occurrence of the Mont Blanc five-neutrino burst. A correlation is found during a period of about two hours roughly centered on the five-neutrino burst, independently between Maryland and Mont Blanc and Rome and Mont Blanc. The probability that these two correlations are due to chance is of the order of between 10 to the -6th and 10 to the -5th.

  14. Italy: Mt. Etna

    Atmospheric Science Data Center

    2013-04-17

    article title:  Multi-angle Portrayals of Mt. Etna's Plume     View Larger Image ... (MISR) capture the energetic eruption of Sicily's Mount Etna volcano on October 29, 2002. Viewing Etna's eruptive activities at ...

  15. Coso MT Site Locations

    DOE Data Explorer

    Doug Blankenship

    2011-05-04

    This data includes the locations of the MT data collected in and around the Coso Geothermal field that covered the West Flank area. These are the data that the 3D MT models were created from that were discussed in Phase 1 of the West Flank FORGE project. The projected coordinate system is NAD 1927 State Plane California IV FIPS 0404 and the Projection is Lambert Conformal Conic. Units are in feet.

  16. ALP-RISK, a smartphone app for collecting data on geomorphic phenomena at high altitude in the Mont Blanc region

    NASA Astrophysics Data System (ADS)

    Ravanel, Ludovic; Deline, Philip

    2014-05-01

    A network of observers (mountain guides, hut keepers and mountaineers) has been created from 2005 for the Mont Blanc massif in order to acquire data on rockfall in permafrost-affected rock walls. This network, fully operational since 2007, is based on observation sheets or oral communications and has documented nearly 350 events with volume between 100 and 45,000 m3. Their analysis confirmed and helped to better understand the role of the permafrost degradation as main triggering factor. To i) reinforce this network, ii) facilitate its observation work and iii) develop it as well in space (the whole Mont Blanc region, or eventually the whole western Alps) as in a thematic point of view (all glacial and periglacial brutal phenomena), the Alp-Risk app has been created in the framework of the Alcotra PrévRisk Mont-Blanc project. The latter (2011-13) has been developed to improve the prevention of individual and collective natural hazards around the Mont Blanc massif. The app was created for I-Phones and Androids in three languages (French, English and Italian) and allows, as intuitively and quickly as possible, transmitting data on natural hazards in high mountain (snow and ice avalanche, landslides and rockfalls, landslides, moraine destabilization, water pocket outburst flood, torrential flood, and others) to both practitioners (observations available directly on the app via an interface web), scientists, and possibly local managers. Alp-Risk thus constitutes a new step for participatory science in the Mont Blanc region.

  17. Investigating K-feldspar Luminescence Thermochronometry for Application in the Mont Blanc Massif

    NASA Astrophysics Data System (ADS)

    Lambert, R.; King, G. E.; Herman, F.; Valla, P.

    2015-12-01

    Luminescence dating has the potential to quantify the recent exhumation history of mountain ranges as a low-temperature thermochronometer. During rock exhumation, electrons get trapped through exposure to ionizing radiation whilst elevated temperatures cause thermally stimulated detrapping. The resulting luminescence signals measured in the laboratory can be used to constrain rock thermal histories through modelling of the kinetic parameters of electron trapping and detrapping. Here, we investigate and model laboratory kinetic processes of the luminescence of K-feldspar and assess their extrapolation over geological timescales. Samples were taken from the actively eroding Mont Blanc massif in the European Alps, along a 12 km long tunnel with ambient temperatures of 10-35 °C. In this setting rapid exhumation rates have been found during the last 2 million years (up to ~2 km/Myr), however, we intend to increase the temporal resolution to sub-Quaternary timescales using luminescence thermochronometry. Infra-red stimulated luminescence signals at 50 °C (IR50) and at 225 °C (post-IR IRSL225) of K-feldspar extracted from Mont Blanc tunnel samples were measured and our first results reveal a thermal signature from which rock cooling rates can be derived. Isothermal decay experiments show non-exponential decay, but interestingly, experiments with a range of regenerative doses reveal first-order kinetics. The observed thermal decay pattern is well-described by a model based on a physically plausible distribution of the density of states. Ultimately, we intend to use the IR50 and post-IR IRSL225 signals of K-feldspar as dual thermochronometers to determine the late-Quaternary cooling history of the Mont Blanc massif. Moreover, the luminescence signals may give insights into local thermal field evolution, before the influence of postglacial hydrothermal flow.

  18. Correlation analysis of the data recorded by the Baksan, Kamioka, and Mont Blanc detectors during SN 1987A

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.

    1989-12-01

    Results are presented on the correlation analysis of data recorded by the Baksan, Kamioka, and Mont Blanc underground detectors during the explosion of the SN 1987. The analysis was performed in order to reinvestigate the observations of two burst of several pulses each occurring several hours before first optical observations. The Mont Blanc computer detected a burst of five pulses about 8 hrs before the first optical observation, followed by a second burst of three pulses about 2 hrs later; Kamioka and Baksan reported observations of a burst made by eleven and five pulses, respectively, delayed by 4.7 hrs in comparison with the Mont Blanc burst. The results of the analysis strongly suggest that the event was real, occurring a few hours before the first optical observation of SN 1987A.

  19. Schatten Matrix Norm Based Polarimetric SAR Data Regularization Application over Chamonix Mont-Blanc

    NASA Astrophysics Data System (ADS)

    Le, Thu Trang; Atto, Abdourrahmane M.; Trouve, Emmanuel

    2013-08-01

    The paper addresses the filtering of Polarimetry Synthetic Aperture Radar (PolSAR) images. The filtering strategy is based on a regularizing cost function associated with matrix norms called the Schatten p-norms. These norms apply on matrix singular values. The proposed approach is illustrated upon scattering and coherency matrices on RADARSAT-2 PolSAR images over the Chamonix Mont-Blanc site. Several p values of Schatten p-norms are surveyed and their capabilities on filtering PolSAR images is provided in comparison with conventional strategies for filtering PolSAR data.

  20. Search for fractionally charged particles in the Mont Blanc LSD scintillation detector

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Antonioli, P.; Badino, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Khalchukov, F. F.; Korolkova, E. V.; Kortchaguin, P. V.; Kortchaguin, V. B.; Kudryavtsev, V. A.; Malguin, A. S.; Marchetti, G.; Periale, L.; Ryassny, V. G.; Ryazhskaya, O. G.; Saavedra, O.; Trinchero, G. C.; Vernetto, S.; Yakushev, V. F.; Zatsepin, G. T.

    1994-02-01

    An analysis of the events recorded by the Mont Blanc Neutrino Scintillation Detector was performed in order to search for fractionally charged particles with |Q| = 1/3and |Q| = 2/3. In a live time of 2378 days, the obtained 90% C. L. upper limits on the fluxes of fractionally charged particles in the core of our detector are Φ(|Q| = 1/3) < 2. 3 10 -13cm-2s-1sr-1and Φ(|Q| = 2/3) < 2. 7 10 -13cm-2s-1sr-1, the best available limits obtained by scintillation counters technique.

  1. Neutrino out-blow from supernova 1987A detected in the Mont Blanc observatory

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.

    The authors discuss the neutrino outflow connected with the event detected in the Mont Blanc Underground Neutrino Observatory on February 23, 1987, and consisting of 5 interactions recorded during 7 seconds. The measured energies of the 5 pulses, the duration of the burst, and the advance of the detection time in comparison with the first optical observations give evidence that the event can be explained in terms of detection of neutrinos emitted during the stellar collapse in the Large Magellanic Cloud, which originated supernova SN 1987A.

  2. Present-day subglacial erosion efficiency inferred from sources and transport of glacial clasts in the North face of Mont Blanc

    NASA Astrophysics Data System (ADS)

    Mugnier, J. L.; Godon, C.; Buoncristiani, J. F.; Paquette, J. L.; Trouvé, E.

    2012-04-01

    The efficiency of erosional processes is classically considered from detrital composition at the outlet of a shed that reflects the rocks eroded within the shed. We adapt fluvial detrital thermochronology (DeCelles et al., 2004) and lithology (Attal and Lavé, 2006) methods to the subglacial streams of the north face of the Mont Blanc. The lithology of this area is composed by a ~303 Ma old granite intruded within an older poly metamorphic complex (orthogneisses). In this study,we use macroscopic criteria (~10 000 clasts) and Ur/Pb dating of zircons (~500 datings of sand grains) to determine the provenance of the sediment transported by the glacier and by the sub-glacial streams. Samples come from sediments collected around the glacier (above, below or laterally), from different bedrocks sources according to the surface flow lines and glacier characteristics (above or below the ELA; temperate or cold), and from different subglacial streams. A comparison between the proportion of granite and orthogneisses in these samples indicates that: 1) the supra load follows the flow lines of the glacier deduced from SAR images correlation and the displacement pattern excludes supra load mixing of the different sources; 2) the transport by the glacier does not mix the clasts issued from the sub-glacial erosion with the clasts issued from supraglacial deposition, except in the lower tongue where supraglacial streams and moulins move the supraglacial load from top to bottom; 3) the erosion rate beneath the glacier is very small: null beneath the cold ice but also very weak beneath the greatest part of the temperate glacier; the erosion increases significantly beneath the tongue, where supraglacial load incorporated at the base favors abrasion; 4) the glacial erosion rate beneath the tongue remains at least five time smaller than the erosion rate coming from non-glacial area. According to our results, we demonstrate that the glaciers of the Mont-Blanc north face protect the top of

  3. Mt. St. Helens Memories.

    ERIC Educational Resources Information Center

    Sharp, Len

    1992-01-01

    Provides a personal account of one science teacher's participation in a teacher workshop in which teachers learned about volcanic development, types of eruption, geomorphology, plate tectonics, volcano monitoring, and hazards created by volcanoes by examining Mt. St. Helens. Provides a graphic identifying volcanoes active since 1975. (MDH)

  4. A re-analysis of 533 rockfalls occurred since 2003 in the Mont Blanc massif for the study of their relationship with permafrost

    NASA Astrophysics Data System (ADS)

    Ravanel, Ludovic; Magnin, Florence; Deline, Philip

    2015-04-01

    Rockfall is one of the main natural hazards in high mountain regions and its frequency is growing, especially since two decades. Collapses at high elevation are with an increasing certainty assumed to be a consequence of the climate change through the warming permafrost. In the Mont Blanc massif, data on present rockfalls (occurrence time when possible, accurate location, topographical and geological settings, volume, weather and snow conditions) were acquired for 2003 and for the period 2007-2014 thanks to a satellite image of the massif and a network of observers in the central part of the massif, respectively. The study of the 533 so-documented rockfalls shows a strong correlation at the year scale between air temperature and rockfall. Along with this data acquisition, a statistical model of the Mean Annual Rock Surface Temperature (MARST) for the 1961-1990 period has been implemented on a 4-m-resolution DEM of the Mont Blanc massif. The model runs with Potential Incoming Solar radiation (PISR) calculated with GIS tools and air temperature parameters computed from Chamonix Météo France records. We cross here the data on rockfalls with the permafrost distribution model to show that: (i) rockfall occurs mainly over modeled negative MARST (context of permafrost); (ii) simulated warm permafrost areas (> -2°C) are the most affected by instabilities; (iii) as the 1961-1990 period is supposed to be representative of the conditions at depth that are not affected by the climate warming during the two last decades, the latest results are mainly valuable for rockfalls related to pluri-decadal signal; and (iv) the higher (close to 0°C) the MARST, the deeper the detachment (possibly related to the deepening of the permafrost active layer). These results and field observations confirm that warming permafrost corresponds to the main required configuration for rockfall triggering at high elevation. In addition, we show that rockfalls for which ice observed in their scar

  5. Influence of fermentation temperature on volatile thiols concentrations in Sauvignon blanc wines.

    PubMed

    Masneuf-Pomarède, Isabelle; Mansour, Chantal; Murat, Marie-Laure; Tominaga, Takatoshi; Dubourdieu, Denis

    2006-05-01

    The effect of Saccharomyces cerevisiae strains on the amount of 4-mercapto-4-methylpentan-2-one, a major varietal aroma of Sauvignon blanc wines, was demonstrated by previous research work. However, the influence of different alcoholic fermentation parameters on the levels of volatile thiols (4-mercapto-4-methylpentan-2-one, 3-mercaptohexan-1-ol and 3-mercaptohexyl acetate) in wines has not yet been investigated. The impact of fermentation temperature on the final amount of volatiles thiols and on some other analytical parameters (ethanol, total acidity, residual sugars, volatile acidity) was determined in a model medium and in grape juice. Interaction between fermentation temperature and yeast strain was also tested. The fermentation temperature influenced the amount of volatile thiols irrespective of the yeast strain used. The final levels of 4MMP and 3MH in model medium and in wines were higher when the alcoholic fermentation is conducted at 20 degrees C than at 13 degrees C. The 3MHA, which was correlated with the amount of 3MH determined in wines, was also higher when the alcoholic fermentation was conducted at 20 degrees C. From a technological point of view, the choice of yeast strain and fermentation temperature has a decisive influence on the concentrations of the varietal aromas of Sauvignon blanc wines.

  6. New radiocarbon chronology of a late Holocene landslide event in the Mont Blanc massif, Italy

    NASA Astrophysics Data System (ADS)

    Hajdas, Irka; Sojc, Ursula; Ivy-Ochs, Susan; Akçar, Naki; Deline, Philip

    2016-04-01

    The Ferret valley Arp Nouva peat bog located in the Mont Blanc massif was critically evaluated since previously published radiocarbon dates have led to controversial conclusions on the formation of the swamp. Radiocarbon dating of roots from three pits of up to 1 m depth was applied to discuss the question whether the historical documented rock avalanche occurring in AD 1717 overran the peat bog or formed it at a later stage. Our results indicate that the rock avalanche formed the Arp Nouva peat bog by downstream blockage of the Bellecombe torrent. Furthermore, careful sample preparation with consequent separation of roots from the bulk peat sample provides possible explanation for the too old 14C ages of bulk peat samples dated previously (Deline and Kirkbride, 2009 and references therein). This work demonstrates that a combined geomorphological and geochronological approach is the most reliable way to reconstruct landscape evolution, especially in light of apparent chronological problems. The key to successful 14C dating is a careful sample selection and the identification of material that might be not ideal for chronological reconstructions. References Deline, Philip, and Martin P. Kirkbride. "Rock avalanches on a glacier and morainic complex in Haut Val Ferret (Mont Blanc Massif, Italy)".Geomorphology 103 (2009): 80-92.

  7. Mineralogy and ore fluid chemistry of the Roc Blanc Ag deposit, Jebilet Hercynian massif, Morocco

    NASA Astrophysics Data System (ADS)

    Essarraj, Samira; Boiron, Marie-Christine; Cathelineau, Michel; Tarantola, Alexandre; Leisen, Mathieu; Hibti, Mohamed

    2017-03-01

    The Roc Blanc Ag deposit is located about 20 km north of Marrakesh city (Morocco) in the Jebilet Hercynian massif. The ore bodies consist of N-S to NE-SW quartz (±carbonates) veins hosted by the Sarhlef marine sediments. These series, deposited in a Devonian-Carboniferous rift basin context, were deformed during the Hercynian orogeny, and submitted to low-grade regional metamorphism. Two major stages of fluid circulation and metal deposition are distinguished on the basis of mineralogical and paleo-fluid studies carried out on quartz and dolomite (microthermometry, Raman spectroscopy, LA-ICP-MS on individual inclusions, and O, H stable isotope data): (i) an early Fe-As stage, characterized by the circulation of metamorphic aqueous-carbonic fluids, under P-T conditions lower than 200 MPa ± 20 MPa and 400 °C respectively, along N-S structures; (ii) the ore stage, characterized by the circulation of a Na-Mg-K ± Ca high salinity brine, poor in gas but rich in metals such as Fe, Sr, Ba, Zn, Pb, ± Cu (salinity ranging from 19.6 wt% to likely more than 30 wt% NaCl equiv.) and the deposition of a sphalerite/dolomite-calcite assemblage; such a fluid likely evolved to a Na-K-(Ca-Mg)-Ag brine, with significant Pb and Sb concentrations and lower Sr, Ba and Zn concentrations than in the preceding fluid (salinity up to 19.4 wt% NaCl equiv.). The Ag content of the second mineralizing brine ranges from 0.9 mmol/kg to 9.4 mmol/kg solution (100 ppm-1000 ppm), whereas the base metal brine is generally Ag poor (up to 1.3 mmol/kg solution: 140 ppm). Dilution of the Ag brine by low salinity fluids (<6 wt% NaCl equiv., and Th from 130° to 230 °C) seems to be the main driving mechanism for the Ag ore deposition at Roc Blanc, with a possible involvement of cooling and reduction reactions in black schists. Base metal and Ag fluids may have circulated at average temperatures around 200 ± 30 °C or slightly higher and under hydrostatic pressures, along dominant E-W structures. The ore

  8. Mt. Spurr's 1992 eruptions

    USGS Publications Warehouse

    1993-01-01

    On 27 June, 1992, the Crater Peak vent on the south side of Mt. Spurr awoke from 39 years of dormancy and burst into sub-plinian eruption after 10 months of elevated seismicity. Two more eruptions followed in August and September. The volcano lies 125 km west of Anchorage, Alaska's largest city and an important international hub for air travel. The Alaska Volcano Observatory (AVO) was able to warn communities and the aviation industry well in advance of these eruptions.

  9. The Spirit of France

    DTIC Science & Technology

    1994-01-01

    self - esteem amongst the French, giving France a greater sense of dignity. Charles de Gaulle sought grandeur to unite France and give the people a sense of common purpose. According to de Gaulle, France’s pursuit of its national interests was not narrow and self-serving, but was

  10. Pre-fermentation fining effects on the aroma chemistry of Marlborough Sauvignon blanc press fractions.

    PubMed

    Parish, Katie J; Herbst-Johnstone, Mandy; Bouda, Flo; Klaere, Steffen; Fedrizzi, Bruno

    2016-10-01

    In the wine industry, fining agents are commonly used with many choices now commercially available. Here the influence of pre-fermentation fining on wine aroma chemistry has been explored. Free run and press fraction Sauvignon blanc juices from two vineyards were fined using gelatin, activated carbon, polyvinylpolypyrrolidone (PVPP) and a combination agent which included bentonite, PVPP and isinglass. Over thirty aroma compounds were quantified in the experimental wines. Results showed that activated carbon fining led to a significant (p<0.05) concentration decrease of hexan-1-ol and linalool in the experimental wines when compared to a control, consistent across all vineyard and fraction combinations. Other aroma compounds were also influenced by fining agent, even if vineyards and press fractions played a crucial role. This study confirmed that fining agents used pre-fermentation can influence wine aroma profiles and therefore needs specific tailoring addressing style and origin of grape.

  11. Orsay, Santeuil and Le Blanc viruses primarily infect intestinal cells in Caenorhabditis nematodes.

    PubMed

    Franz, Carl J; Renshaw, Hilary; Frezal, Lise; Jiang, Yanfang; Félix, Marie-Anne; Wang, David

    2014-01-05

    The discoveries of Orsay, Santeuil and Le Blanc viruses, three viruses infecting either Caenorhabditis elegans or its relative Caenorhabditis briggsae, enable the study of virus-host interactions using natural pathogens of these two well-established model organisms. We characterized the tissue tropism of infection in Caenorhabditis nematodes by these viruses. Using immunofluorescence assays targeting proteins from each of the viruses, and in situ hybridization, we demonstrate viral proteins and RNAs localize to intestinal cells in larval stage Caenorhabditis nematodes. Viral proteins were detected in one to six of the 20 intestinal cells present in Caenorhabditis nematodes. In Orsay virus-infected C. elegans, viral proteins were detected as early as 6h post-infection. The RNA-dependent RNA polymerase and capsid proteins of Orsay virus exhibited different subcellular localization patterns. Collectively, these observations provide the first experimental insights into viral protein expression in any nematode host, and broaden our understanding of viral infection in Caenorhabditis nematodes.

  12. Limits on low-energy neutrino fluxes with the Mont Blanc liquid scintillator detector

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Antonioli, P.; Badino, G.; Bologna, G.; Castagnoli, C.; Castellina, A.; Dadykin, V. L.; Fulgione, W.; Galeotti, P.; Khalchukov, F. F.; Korolkova, E. V.; Kortchaguin, P. V.; Kortchaguin, V. B.; Kudryavtsev, V. A.; Malguin, A. S.; Periale, L.; Ryassny, V. G.; Ryazhskaya, O. G.; Saavedra, O.; Trinchero, G.; Vernetto, S.; Yakushev, V. F.; Zatsepin, G. T.

    1992-11-01

    The LSD liquid scintillation detector has been operating since 1985 as an underground neutrino observatory in the Mont Blanc Laboratory with the main objective of detecting antineutrino bursts from collapsing stars. In August 1988 the construction of an additional lead and borex paraffin shield considerably reduced the radioactive background and increased the sensitivity of the apparatus. In this way the search for steady fluxes of low-energy neutrinos of different flavours through their interactions with free protons and carbon nuclei of the scintillator was made possible. No evidence for a galactic collapse was observed during the whole period of measurement. The corresponding 90% c.l. upper limit on the galactic collapses rate is 0.45 y -1 for a burst duration of ΔT ⩽ 10 s. After analysing the last 3 years data, the following 90% c.l. upper limits on the steady neutrino and antineutrino fluxes were obtained:

  13. Grape cluster microclimate influences the aroma composition of Sauvignon blanc wine.

    PubMed

    Martin, Damian; Grose, Claire; Fedrizzi, Bruno; Stuart, Lily; Albright, Abby; McLachlan, Andrew

    2016-11-01

    New Zealand Sauvignon blanc (SB) wines are characterised by a distinctive combination of tropical-fruity and green-herbaceous aromatic compounds. The influence of sunlight exposure of grape clusters on juice and wine composition was investigated, with the aim of manipulating aromatic compounds in SB wine. In the absence of basal leaf removal SB clusters naturally exposed to sunlight were riper than shaded clusters, evidenced by higher total soluble solids (TSS) and proline, and lower malic acid, 3-isobutyl-2-methoxypyrazine (IBMP) and arginine. Volatile thiols in wines did not differ between shaded and exposed clusters. At equivalent TSS, cluster exposure had little or no effect on malic acid concentration. Conversely, wine from shaded clusters had almost double the IBMP concentration of wine from exposed clusters at equivalent TSS. The effects on SB juice and wine composition of natural variations in cluster microclimate are not comparable with the effects of cluster exposure created through leaf removal.

  14. The use of ground based photogrammetry for the monitoring of seasonal movement of a glacier: the case study of Planpincieux Glacier, Grandes Jorasses massif, Mont Blanc

    NASA Astrophysics Data System (ADS)

    Giordan, Daniele; Dell'Anese, Federico; Allasia, Paolo; Vagliasindi, Marco; Motta, Elena

    2016-04-01

    In September 2013, an experimental low cost monitoring station has been installed on the top of Mt. de La Saxe (Val Ferret, Aosta Valley, NW of Italy) to monitor the Planpincieux Glacier, located on the Italian side of Mont Blanc Massif. This system is based on two commercial APS-C DSLR cameras equipped with a 297 mm and 120 mm optical zoom respectively. Every hour cameras automatically acquire pictures of the lower part of the glacier, which showed to be the most active. The available dataset is analyzed using both change-detection and pixel-offset techniques, to detect the main surface changes over time, as well as to retrieve quantitative measurements of the glacier displacements. The system is able to work throughout the year. The available dataset has been used to analyze the daily evolution of the lower part of the glacier over the May-November period (when the glacier is free from snow) both in 2014 and 2015. The pixel-offset approach allows to measure the displacement of different parts of the glacier and to describe its seasonal evolution. Furthermore, change detection algorithm allows highlighting sudden changes of the scene, usually due to icefalls. The available dataset shows that the displacement rate of the glacier increases during the warm season, that in 2014 it was higher than in 2015, and that it was distributed in a different way. Actually, in 2015, the maximum rate was reached in August, whereas in 2014 the measured summer velocity was lower but it lasted over the months of July, August and September. The results have been validated using different ground based SARs, both in 2014 and 2015. Here we present the results of a three years monitoring, demonstrating the efficiency of pixel-offset and change-detection techniques for contactless monitoring of unreachable glacier surfaces. Furthermore, we present cross-analysis, considering displacements vs. weather measurements, in order to understand glaciers dynamics.

  15. Correlation between background events detected by the Mont Blanc neutrino detector and by the Baksan Neutrino Telescope on 23.02.1987.

    NASA Astrophysics Data System (ADS)

    Alexeyev, E. N.; Alexeyeva, L. N.; Klimenko, N. F.; Kogaj, I. M.; Krivosheina, I. V.; Poddubny, V. A.; Zakidyshev, V. N.

    The Mont Blanc and Baksan neutrino detector data were compared for the period 00:00 - 10:00 UT on 23 February 1987. During one hour (1:45 - 2:45 UT) a correlation between Mont Blanc events, which are mainly caused by natural radioactivity, and Baksan high energy cosmic ray muons has been found. This correlation can probably be associated with SN 1987A.

  16. New structural field data on the timing and kinematics of deformation and exhumation of the Mont Blanc massif

    NASA Astrophysics Data System (ADS)

    Egli, Daniel; Mancktelow, Neil

    2010-05-01

    The Mont Blanc massif is one of the external crystalline massifs, which represent the basement of the former European continental margin and therefore belong to the Helvetic domain. It mainly consists of polymetamorphic Late Proterozoic to Early Paleozoic gneisses intruded by the Variscan Mont Blanc granite (Von Raumer et al. 1993). The timing and kinematics of deformation and exhumation of the Mont Blanc massif is a controversial topic and various models have been proposed. Low-temperature thermochronology studies provide an extensive data set for estimating exhumation rates in Neogene times (e.g. Seward & Mancktelow 1994; Leloup et al. 2005; Glotzbach et al. 2008), but detailed structural studies to critically asses and constrain the proposed kinematic models are largely lacking. Glotzbach et al. (2008) show that the exhumation is episodic, with rates changing from relatively fast (~2.5 km/Ma before 6 Ma) to a slow phase (<0.5 km/Ma between 6 and 3.5 Ma), in turn followed by acceleration to ~1 km/Ma after 3 Ma. Our study presents new structural data from the south-eastern side of the Mont Blanc massif and the adjacent sediments and addresses the tectonic evolution and late stage exhumation history of the massif. The goal is to assess the importance of tectonics versus climate for controlling exhumation, as well as to establish the overall geometry of uplift (2D pop-up, 3D dextral transpressive model, large scale backfolding). A major back-thrust was proposed by previous authors ("Mont Blanc back-thrust", e.g. Leloup et al. 2005, Rolland et al. 2007), characterized as a relatively steeply north-west dipping thrust bringing the Mont Blanc basement back over the tectonostratigraphically higher Helvetic and Ultrahelvetic metasediments. 40Ar¬-39Ar dating of white micas interpreted to have grown during movement on the Mont Blanc back-thrust indicates an initiation of movement around 16 Ma (Rolland et al. 2007). Leloup et al. (2005) suggest a reactivation of this

  17. Mt. Vesuvius, Italy

    NASA Technical Reports Server (NTRS)

    2001-01-01

    This ASTER image of Mt. Vesuvius Italy was acquired September 26, 2000, and covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. The image is centered at 40.8 degrees north latitude, 14.4 degrees east longitude.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  18. Mt. St. Helens

    NASA Technical Reports Server (NTRS)

    2001-01-01

    [figure removed for brevity, see original site] [figure removed for brevity, see original site] Figure 1 Movie

    This 3-D anaglyph image of Mt. St. Helens volcano combines the nadir-looking and back-looking band 3 images of ASTER. To view the image in stereo, you will need blue-red glasses. Make sure to look through the red lens with your left eye. Figure 1: This ASTER image of Mt. St. Helens volcano in Washington was acquired on August 8, 2000 and covers an area of 37 by 51 km. Mount Saint Helens, a volcano in the Cascade Range of southwestern Washington that had been dormant since 1857, began to show signs of renewed activity in early 1980. On 18 May 1980, it erupted with such violence that the top of the mountain was blown off, spewing a cloud of ash and gases that rose to an altitude of 19 kilometers. The blast killed about 60 people and destroyed all life in an area of some 180 square kilometers (some 70 square miles), while a much larger area was covered with ash and debris. It continues to spit forth ash and steam intermittently. As a result of the eruption, the mountain's elevation decreased from 2,950 meters to 2,549 meters. The image is centered at 46.2 degrees north latitude, 122.2 degrees west longitude.

    Movie: The simulated fly-over was produced by draping ASTER visible and near infrared image data over a digital topography model, created from ASTER's 3-D stereo bands. The color was computer enhanced to create a natural color image, where the vegetation appears green. The topography has been exaggerated 2 times to enhance the appearance of the relief.

    The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

  19. Environmental factors controlling the seasonal variability in particle size distribution of modern Saharan dust deposited off Cape Blanc

    NASA Astrophysics Data System (ADS)

    Friese, Carmen A.; van der Does, Michèlle; Merkel, Ute; Iversen, Morten H.; Fischer, Gerhard; Stuut, Jan-Berend W.

    2016-09-01

    The particle sizes of Saharan dust in marine sediment core records have been used frequently as a proxy for trade-wind speed. However, there are still large uncertainties with respect to the seasonality of the particle sizes of deposited Saharan dust off northwestern Africa and the factors influencing this seasonality. We investigated a three-year time-series of grain-size data from two sediment-trap moorings off Cape Blanc, Mauritania and compared them to observed wind-speed and precipitation as well as satellite images. Our results indicate a clear seasonality in the grain-size distributions: during summer the modal grain sizes were generally larger and the sorting was generally less pronounced compared to the winter season. Gravitational settling was the major deposition process during winter. We conclude that the following two mechanisms control the modal grain size of the collected dust during summer: (1) wet deposition causes increased deposition fluxes resulting in coarser modal grain sizes and (2) the development of cold fronts favors the emission and transport of coarse particles off Cape Blanc. Individual dust-storm events throughout the year could be recognized in the traps as anomalously coarse-grained samples. During winter and spring, intense cyclonic dust-storm events in the dust-source region explained the enhanced emission and transport of a larger component of coarse particles off Cape Blanc. The outcome of our study provides important implications for climate modellers and paleo-climatologists.

  20. Mt. Etna, Italy

    NASA Technical Reports Server (NTRS)

    2002-01-01

    On Sunday, November 3, 2002, Mt. Etna's ash-laden plume was imaged by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. The plume is seen blowing toward the south-southeast, over the city and airport of Catania, Sicily. The previous day, the plume was blowing toward the northwest, and posed no hazard to Catania. The current eruption of Mt. Etna, Europe's most active volcano, began on October 27. These sorts of observations from space may help civil defense authorities mitigate hazards from active eruptions. Space data may also help scientists evaluate the behavior and effects volcanic eruptions have on our global climate system.

    With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER images Earth to map and monitor the changing surface of our planet.

    ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

    The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

    Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, Calif., is the U.S. science team leader; Bjorn Eng of JPL is the project manager. The Terra mission is part of NASA's Earth Science

  1. Nitrogen and carbon assimilation by Saccharomyces cerevisiae during Sauvignon blanc juice fermentation.

    PubMed

    Pinu, Farhana R; Edwards, Patrick J B; Gardner, Richard C; Villas-Boas, Silas G

    2014-12-01

    To investigate the assimilation and production of juice metabolites by Saccharomyces cerevisiae during winemaking, we compared the metabolite profiles of 63 Sauvignon blanc (SB) grape juices collected over five harvesting seasons from different locations of New Zealand before and after fermentation by the commercial wine yeast strain EC1118 at 15 °C. Metabolite profiles were obtained using gas chromatography-mass spectrometry and nuclear magnetic resonance and the oenological parameters were determined by Fourier transform infrared spectroscopy. Our results revealed that the amino acids threonine and serine were the most consumed organic nitrogen sources, while proline and gamma-aminobutyric acid were the least consumed amino acids during SB juice fermentation. Saccharomyces cerevisiae metabolised some uncommon nitrogen sources (e.g. norleucine, norvaline and pyroglutamic acid) and several organic acids, including some fatty acids, most likely after fermenting the main juice sugars (glucose, fructose and mannose). However, consumption showed large variation between juices and in some cases between seasons. Our study clearly shows that preferred nitrogen and carbon sources were consumed by S. cerevisiae EC1118 independent of the juice fine composition, whilst the consumption of other nutrient sources mainly depended on the concentration of other juice metabolites, which explains the uniqueness of each barrel of wine.

  2. Atmospheric heavy metals in high altitude surface snows from Mont Blanc, French Alps

    NASA Astrophysics Data System (ADS)

    Batifol, Francoise M.; Boutron, Claude F.

    We present here the results of the analysis of various surface snow samples collected in the massif of Mont Blanc, French Alps, at three locations whose altitude ranges from 3560 to 4785 m a. s l. These samples were collected using ultra-clean techniques similar to the ones developed for Greenland and Antarctic studies. They were analysed for Pb, Cd, Cu, Zn, Ag, Na, Mg, K, Ca, Fe, Al and Mn by Graphite Furnace Atomic Absorption in clean room conditions. Measured concentrations are very low, then confirming the extreme purity of high altitude snow in the Alps. Principal components factor analysis of the data suggest a crustal source for Na, Mg, K, Ca, Fe, Mn and Al; heavy metals Pb, Cd, Cu, Zn and Ag are found on the other hand to be derived from one or several sources independent of the crustal source. Measured concentrations in snow appear to be closely related to those previously published by other authors for local aerosols.

  3. Mt. Etna Eruption

    NASA Technical Reports Server (NTRS)

    2002-01-01

    [figure removed for brevity, see original site] [figure removed for brevity, see original site] Figure 1: Vis/NIR Image CloseupFigure 2: Difference Image

    October 2002 Mt. Etna, a volcano on the island of Sicily, erupted on October 26, 2002. Preliminary analysis of data taken by the Atmospheric Infrared Sounder (AIRS) on NASA's Aqua satellite on October 28 shows the instrument can provide an excellent means to study the evolution and structure of the sulfur dioxide (SO2) plume emitted from volcanoes. These data also demonstrate that AIRS can be used to obtain the total mass of SO2 injected into the atmosphere during a volcanic event, information that may help us to better understand these dangerous natural occurrences in the future.

    This image was made from a sensor on the AIRS instrument that is sensitive to the visible and near-infrared portions of the spectrum. The visible/near infrared data show the smoke plume from Mt. Etna. The view is of Europe and the central Mediterranean with Italy in the center. Since the visible/near infrared sensor on AIRS is sensitive to wavelengths that are different than the human eye, vegetated regions appear red (compare the red color of Europe with the tan desert of North Africa in the lower left). Figure 1 is a closer view of Sicily and shows a long, brownish smoke plume extending across the Mediterranean to Africa. This is consistent with the enhanced feature in the difference image in Figure 2 and helps validate the information inferred from that image.

    Figure 2 clearly shows the SO2 plume. This image was created by comparing data taken at two different frequencies, or channels, and creating one image that highlights the differences between these two channels. Both channels are sensitive to water vapor, but one of the channels is also sensitive to SO2. By subtracting out the common water vapor signal in both channels, the SO2 feature remains and shows up as an enhancement in the difference image.

    The

  4. MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective

    PubMed Central

    Liu, Jiabei; Clough, Shannon J.; Hutchinson, Anthony J.; Adamah-Biassi, Ekue B.; Popovska-Gorevski, Marina; Dubocovich, Margarita L.

    2016-01-01

    Melatonin, or 5-methoxy-N-acetyltryptamine, is synthesized and released by the pineal gland and locally in the retina following a circadian rhythm, with low levels during the day and elevated levels at night. Melatonin activates two high-affinity G protein–coupled receptors, termed MT1 and MT2, to exert beneficial actions in sleep and circadian abnormality, mood disorders, learning and memory, neuroprotection, drug abuse, and cancer. Progress in understanding the role of melatonin receptors in the modulation of sleep and circadian rhythms has led to the discovery of a novel class of melatonin agonists for treating insomnia, circadian rhythms, mood disorders, and cancer. This review describes the pharmacological properties of a slow-release melatonin preparation (i.e., Circadin®) and synthetic ligands (i.e., agomelatine, ramelteon, tasimelteon), with emphasis on identifying specific therapeutic effects mediated through MT1 and MT2 receptor activation. Discovery of selective ligands targeting the MT1 or the MT2 melatonin receptors may promote the development of novel and more efficacious therapeutic agents. PMID:26514204

  5. MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective.

    PubMed

    Liu, Jiabei; Clough, Shannon J; Hutchinson, Anthony J; Adamah-Biassi, Ekue B; Popovska-Gorevski, Marina; Dubocovich, Margarita L

    2016-01-01

    Melatonin, or 5-methoxy-N-acetyltryptamine, is synthesized and released by the pineal gland and locally in the retina following a circadian rhythm, with low levels during the day and elevated levels at night. Melatonin activates two high-affinity G protein-coupled receptors, termed MT1 and MT2, to exert beneficial actions in sleep and circadian abnormality, mood disorders, learning and memory, neuroprotection, drug abuse, and cancer. Progress in understanding the role of melatonin receptors in the modulation of sleep and circadian rhythms has led to the discovery of a novel class of melatonin agonists for treating insomnia, circadian rhythms, mood disorders, and cancer. This review describes the pharmacological properties of a slow-release melatonin preparation (i.e., Circadin®) and synthetic ligands (i.e., agomelatine, ramelteon, tasimelteon), with emphasis on identifying specific therapeutic effects mediated through MT1 and MT2 receptor activation. Discovery of selective ligands targeting the MT1 or the MT2 melatonin receptors may promote the development of novel and more efficacious therapeutic agents.

  6. Coincidences among the data recorded by the Baksan, KAMIOKA and Mont Blanc underground neutrino detectors, and by the Maryland and Rome gravitational-wave detectors during Supernova 1987 A

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Castellina, A.; Fulgione, W.; Trinchero, G.; Vernetto, S.

    1991-04-01

    Data recorded with neutrino detectors at Mont Blanc, Kamioka, and Baksan and with gravitational wave detectors in Maryland and Rome are analyzed. An attempt is made to find correlations associated with SN 1987 A. The time when an excess of coincidences is found is centered at a 5-pulse burst detected at Mont Blanc.

  7. Repeated Holocene rock avalanches onto the Brenva Glacier, Mont Blanc massif, Italy: A chronology

    NASA Astrophysics Data System (ADS)

    Deline, Philip; Akçar, Naki; Ivy-Ochs, Susan; Kubik, Peter W.

    2015-10-01

    Infrequent rock avalanches (volume ≥1 Mm3) are long-runout processes, especially when travelling onto a glacier, that may threaten populated mountain valleys. Rock avalanches also have strong implications are for relief generation and destruction though time. Both consequences make reconstruction and dating of past events crucial, but dense clusters of events documented in one basin that may improve our knowledge of rock-avalanche frequency and triggering are very rare. Here we propose a chronology of seven of the rock-ice avalanches that affected a steep glacier basin on the southeast side of the Mont Blanc during the late Holocene. A geomorphological study of the runout deposits on the valley floor and the opposite side was combined with the analysis of historical sources and the use of absolute and relative dating methods, especially surface exposure dating with cosmogenic nuclides of 18 granite boulders from two deposits. These rock-ice avalanches are dated AD 1997 and 1920, with a rock volume in the range 2.4-3.6 and 2 × 106 m3, respectively; AD 1767, with a slightly shorter runout; AD 1000-1200, with a longer runout; c. AD 500, the runout of which is uncertain; c. 2500 BP, the determination of which is indirect; and c. 3500 years, with the longest runout. There is no distinct relationship between climatic periods and occurrence of these rock avalanches. Even for the two best documented ones, modelling suggests that the 1997 scar was characterized by a permafrost close to 0 °C, whereas in contrast, the 1920 scar was on the contrary located in cold permafrost.

  8. Episodic exhumation and relief growth in the Mont Blanc massif, Western Alps from numerical modelling of thermochronology data

    NASA Astrophysics Data System (ADS)

    Glotzbach, C.; van der Beek, P. A.; Spiegel, C.

    2011-04-01

    The Pliocene-Quaternary exhumational and topographic evolution of the European Alps and its potential climatic and tectonic controls remain a subject of controversy. Here, we apply inverse numerical thermal-kinematic modelling to a spatially dense thermochronological dataset (apatite fission-track and (U-Th)/He) of both tunnel and surface samples across the Mont Blanc massif in the Western Alps, complemented by new zircon fission-track data, in order to better quantify its Neogene exhumation and relief history. Age-elevation relationships and modelling results show that an episodic exhumation scenario best fits the data. Initiation of exhumation in the Mont Blanc massif at 22 ± 2 Ma with a rate of 0.8 ± 0.15 km/Myr is probably related to NW-directed thrusting during nappe emplacement. Exhumation rates decrease at 6 ± 2 Ma to values of 0.15 ± 0.65 km/Myr, which we interpret to be the result of a general decrease in convergence rates and/or extensive exposure of less erodible crystalline basement rocks from below more easily erodible Mesozoic sediments. Finally, local exhumation rates increase up to 2.0 ± 0.6 km/Myr at 1.7 ± 0.8 Ma. Modelling shows that this recent increase in local exhumation can be explained by valley incision and the associated increase in relief at 0.9 ± 0.8 Ma, leading to erosional unloading, isostatic rebound and additional rock uplift and exhumation. Given the lack of tectonic activity as evidenced by constant thermochronological ages along the tunnel transect, we suggest that the final increase in exhumation and relief in the Mont Blanc massif is the result of climate change, with the initiation of mid-Pleistocene glaciations leading to rapid valley incision and related local exhumation.

  9. Hurricanes Frances and Ivan

    Atmospheric Science Data Center

    2014-05-15

    article title:  Cloud Height Maps for Hurricanes Frances and Ivan     ... predict the intensity and amount of rainfall associated with hurricanes still requires improvement, especially on the 24 to 48 hour ...

  10. France in Black Africa,

    DTIC Science & Technology

    1989-01-01

    disease and the lack of support from the metropole (mother 4 France Acquires and Adninisters an Empire country), French rule over the small...as socially 9 France in Black Africa undesirable in an officer corps still dominated by the aristocracy; they were apt to be republicans, anticler- ics ...the interior. Endemic tropical diseases like yellow fever and malaria claimed a high proportion of Europeans who attempted to live in this region up to

  11. Mt. SAC Research Briefs, 2000.

    ERIC Educational Resources Information Center

    Mt. SAC Research Briefs, 2000

    2000-01-01

    These Research Briefs examine Mt. San Antonio College District's (MSAC's) (California) enrollment trends. Over the last few years, the district has drawn a large number of students from surrounding areas; however, there are concerns as to whether this fact will remain the same as new forms of educational techniques such as distance education and…

  12. English Teaching Profile: France.

    ERIC Educational Resources Information Center

    British Council, London (England). English Language and Literature Div.

    This review of the status of English language instruction in France provides an overview of the role of English in the society in general and outlines the status of English in the educational system at the elementary, secondary, higher, and vocational levels. The following topics are covered: instruction in English for special purposes, the…

  13. France. [CME Country Reports].

    ERIC Educational Resources Information Center

    Council of Europe, Strasbourg (France). Documentation Center for Education in Europe.

    In France, the 1882 Compulsory Education Act includes both French and foreign children. Since then, the need to go further than this general principle of non-discrimination and to undertake specific action for immigrants, both adults and children, has been recognized. Since 1970, the Ministry of Education has been directly responsible for this…

  14. Urban Sociology in France.

    ERIC Educational Resources Information Center

    Amiot, Michel

    1986-01-01

    Divides the history of urban sociology in France into three periods: (1) functionalism, which lasted from 1910 until the 1960s, (2) neo-Marxist socioeconomics lasting from 1968 until 1979, and (3) anthropological approach which is still dominant. Reviews theoretical perspectives and research characteristic of each period. (JDH)

  15. Technological Elites in France.

    ERIC Educational Resources Information Center

    Trilling, Leon

    1988-01-01

    Compares the training and activity of scientists and engineers in France and the United States. Describes the French higher education system including the features and curriculum design of the "grandes ecoles." Discusses the differences in the role of government to research and development between the two nations. (YP)

  16. [Psychosocial rehabilitation in France].

    PubMed

    Vidon, Gilles

    2015-01-01

    For a long time in France, readaptation and reinsertion have been considered separately. While readaptation focuses on the way the patient "adapts again", reintegration looks at the place of the readaptation, the society or the group. Today, psychosocial rehabilitation encompasses both of these notions by taking into account the medical and social aspects.

  17. [Anesthesiologists in France].

    PubMed

    Mizuno, Ju; Hanaoka, Kazuo; Merckx, Paul; Bonneville, Claire Tae; Kavafyan, Juliette; Mantz, Jean

    2007-03-01

    We review some anesthesiologist's curriculum and demographic characteristics in France to the community of Japanese anesthesiologists. To become a certified anesthesiologist and an intensive care physician currently requires six years' medical education, passing national medical examination, and five years' special training as an intern of anesthesiology and intensive care. This educational course was started in 1984. There are 7942 certified anesthesiologists in France in 1999. The average age is 45.9 years and the ratio of female is 35.3%. Approximately two thirds of certified anesthesiologists are working in public institutions. 89% is full-time workers. More than half of certified anesthesiologists actually participate in daily intensive care practice. The number of certified anesthesiologists has been increasing gradually totaling 10,062 persons in 2005. The number of certified anesthesiologists per ten thousands general population is 1.7 persons and the corresponding ratio to all medical doctors is 4.8%. Working hours and holidays are regulated by the French Labour Law. The anaesthesiologist often works in a team with a nurse anaesthetist. The number of certified anesthesiologists in France is larger than that in Japan. Management of anesthesia in France seems to have an advantage in manpower.

  18. [Primary care in France].

    PubMed

    Sánchez-Sagrado, T

    2016-01-01

    The poor planning of health care professionals in Spain has led to an exodus of doctors leaving the country. France is one of the chosen countries for Spanish doctors to develop their professional career. The French health care system belongs to the Bismarck model. In this model, health care system is financed jointly by workers and employers through payroll deduction. The right to health care is linked to the job, and provision of services is done by sickness-funds controlled by the Government. Primary care in France is quite different from Spanish primary care. General practitioners are independent workers who have the right to set up a practice anywhere in France. This lack of regulation has generated a great problem of "medical desertification" with problems of health care access and inequalities in health. French doctors do not want to work in rural areas or outside cities because "they are not value for money". Medical salary is linked to professional activity. The role of doctors is to give punctual care. Team work team does not exist, and coordination between primary and secondary care is lacking. Access to diagnostic tests, hospitals and specialists is unlimited. Duplicity of services, adverse events and inefficiencies are the norm. Patients can freely choose their doctor, and they have a co-payment for visits and hospital care settings. Two years training is required to become a general practitioner. After that, continuing medical education is compulsory, but it is not regulated. Although the French medical Health System was named by the WHO in 2000 as the best health care system in the world, is it not that good. While primary care in Spain has room for improvement, there is a long way for France to be like Spain.

  19. SN 1987 A - Correlations between the Maryland and Rome gravitational wave detector data and the Mont Blanc and KAMIOKANDE neutrino detector data

    NASA Astrophysics Data System (ADS)

    Pallottino, G. V.

    1990-02-01

    The paper describes the analysis of data obtained in the period 12 h of February 22, 1987 to 6 h of February 23, 1987, that includes the time of neutrino observation with the Mont Blanc detector during SN 1987 A. A very significant correlation has been observed among the data of the above detectors in a period of one or two hours which includes the time of the Mont Blanc 5-neutrino observation. The correlation between the gravitational wave detector data and the Kamiokande data is found if a time of 7.8 s is added to the Kamioka recorded time; this is very close to the time difference, 6.2 s, between the IMB and Kamioka large neutrino bursts observed at about 7 h 35 min.

  20. Correlation between the Maryland and Rome gravitational-wave detectors and the Mont Blanc, Kamioka and IMB particle detectors during SN 1987A.

    NASA Astrophysics Data System (ADS)

    Aglietta, M.; Castellina, A.; Fulgione, W.; Trinchero, G.; Vernetto, S.; Astone, P.; Badino, G.; Bologna, G.; Bassan, M.; Coccia, E.; Modena, I.; Bonifazi, P.; Castellano, M. G.; Visco, M.; Castagnoli, C.; Galeotti, P.; Saavedra, O.; Cosmelli, C.; Frasca, S.; Pallottino, G. V.; Pizzella, G.; Rapagnani, P.; Ricci, F.; Majorana, E.; Gretz, D.; Weber, J.; Wilmot, G.

    1991-11-01

    Following a previously found correlation between the gravitational-wave detectors and the Mont Blanc particle detector, the authors have searched for a similar correlation between the data of the experiments mentioned in the title. They have found that both the Kamioka and the IMB data have a correlation with the gravitational-wave data that occurs with the same characteristics and at the same time of that already found with Mont Blanc. This correlation extends for a period of one or two hours centred at the hour 2:45 UT of 23 February 1987. It shows that the particle detector signals are delayed with respect to the gravitational-wave detector signals by (1.2±0.5)s. The probability that the additional correlation due to Kamioka and IMB is only accidental is estimated of the order of 10-3 or 10-4.

  1. European security and France

    SciTech Connect

    deRose, A.

    1985-01-01

    A French authority on security argues for new European initiatives in the face of the ''danger represented by Soviet military power deployed in support of an imperialistic ideology.'' His proposals, including the strengthening of conventional forces without abandoning the option of the first use of nuclear weapons, are meant to give substance to President Mitterrand's declaration in 1983: ''The European nations now need to realize that their defense is also their responsibility....'' A part of the increasingly important debate in France over defense policy in Europe.

  2. Incineration of municipal and assimilated wastes in France: assessment of latest energy and material recovery performances.

    PubMed

    Autret, Erwan; Berthier, Francine; Luszezanec, Audrey; Nicolas, Florence

    2007-01-31

    Incineration has an important place in waste management in France. In 2003, around 130 incineration plants have treated 12.6 Mt of non-dangerous waste, mainly composed of household waste (10.8 Mt), non-dangerous waste from industry, business, services (1.0 Mt), sewage sludge (0.2 Mt) or clinical waste (0.1 Mt). The incineration of these wastes generated 3.0 Mt of bottom ash of which 2.3 Mt were used for roads construction and 0.2 Mt of ferrous and non-ferrous metal were recycled. It also produced 2,900,000 MWh of electricity, of which 2,200,000 MWh were sold to Electricité de France (EDF) and 9,100,000 MWh of heat, of which 7,200,000 MWh were sold to private or public users. These French incinerators of non-hazardous waste are currently being thoroughly modernized, thus making possible the consolidation and the enhancement of their environmental and energy performance. This process is related to the implementation of the European Directive 2000/76/CE whose expiration date is 28 December 2005. Upon request of ADEME, the engineering company GIRUS has realised the first technical and economical evaluation of works necessary to bring incinerators into compliance. The financial estimations, carried out in 30 June 2003, show that the investments to be devoted could reach 750 million euros. This assessment shed new light on the situation of non-hazardous waste incinerators, including an identification and a rank ordering for each incinerator of the most frequent and the most complex non-conformities to be solved in term of cost and delay. At last, this assessment gives the solutions for each non-compliance.

  3. Thermal and structural evolution of the external Western Alps: Insights from (U-Th-Sm)/He thermochronology and RSCM thermometry in the Aiguilles Rouges/Mont Blanc massifs

    NASA Astrophysics Data System (ADS)

    Boutoux, A.; Bellahsen, N.; Nanni, U.; Pik, R.; Verlaguet, A.; Rolland, Y.; Lacombe, O.

    2016-06-01

    In the Western Alps, the External Crystalline Massifs (ECM) are key places to investigate the kinematics and thermal structure of a collisional crustal wedge, as their paleo-brittle/ductile transition is now exhumed at the surface. New (U-Th-Sm)/He data on zircon and new Raman Spectroscopy on Carbonaceous Material (RSCM) data from the Aiguilles Rouges and the Mont Blanc massifs, coupled to HeFTy thermal modeling, constrain the thermal evolution and exhumation of the massifs. In the cover of the Aiguilles Rouges massif, we found that the maximal temperature was about 320 °C (+/- 25 °C), close to the maximal temperature reached in the cover of the Mont Blanc massif ( 350 °C +/- 25 °C). We show that, after a fast heating period, the thermal peak lasted 10-15 Myrs in the Mont Blanc massif, and probably 5-10 Myrs in the Aiguilles Rouges massif. This thermal peak is synchronous with crustal shortening documented in the basement. (U-Th-Sm)/He data and thermal modeling point toward a coeval cooling of both massifs, like other ECM, at around 18 Ma +/- 1 Ma. This cooling was related to an exhumation due to the initiation of frontal crustal ramps below the ECM, quite synchronously along the Western Alps arc.

  4. Functional MT + lesion impairs contralateral motion processing.

    PubMed

    Moo, Lauren R; Emerton, Britt C; Slotnick, Scott D

    2008-07-01

    Human motion processing region MT + is retinotopically organized with perception of and attention to motion in the right visual field preferentially associated with left MT + activity and vice versa. However, the degree to which MT + is crucial for motion processing is uncertain. We report an epilepsy patient with visual symptoms early in his seizure evolution and a left temporal-occipital seizure onset electrographically in whom we hypothesized a functional left MT + lesion. The patient was impaired in his right but not left visual field on a hemifield motion attention task and demonstrated worse performance on a hemifield picture identification task when pictures implying motion were presented in the right as opposed to the left visual field. Functional MRI (fMRI) during a full-field motion detection task activated right MT + but failed to activate left MT + despite activating both left and right MT + in each of 10 controls. Furthermore, fMRI during a hemifield motion attention task also showed a lack of left MT + attention effects in the patient. Together these results suggest that MT + is necessary for normal motion processing.

  5. Battle of France WWII

    NASA Astrophysics Data System (ADS)

    Gadhath, Arpitha Rao

    The purpose of this thesis is to build an interactive Geographical Information System (GIS) tool, relating to the series of events that occurred during the Battle of France World War II. The tool gives us an insight about the countries involved in the battle, their allies and their strategies. This tool was created to use it as a one stop source of information regarding all the important battles that took place, which lead to the fall of France. The tool brings together the maps of all the countries involved. Integrated with each map is the data relevant to that map. The data for each country includes the place of attack, the strategies used during the attack, and the kind of warfare. The tool also makes use of HTML files to give all the information, along with the images from the time of the war and a footage which explains everything about the particular battle. The tool was build using JAVA, along with the use of MOJO (Map Objects Java Objects) to develop Maps of each of the countries. MOJO is developed by ESRI (Environmental Science Research Institute) which makes it easier to add data to the maps. It also makes highlighting important information easier making use of pop-up windows, charts and infographics. HTML files were designed making use of the open-source template developed by Bootstrap. The tool is built in such a way that the interface is simple and easy for the user to use and understand.

  6. Legionnaires' disease in France.

    PubMed

    Campèse, C; Descours, G; Lepoutre, A; Beraud, L; Maine, C; Che, D; Jarraud, S

    2015-03-01

    The aim of this review was to describe the current knowledge of Legionnaires' disease (LD) illustrated by the epidemiological situation in France in 2013. LD is a severe pneumonia commonly caused by Legionella pneumophila serogroup 1. The diagnosis is usually based on the urinary antigen test. This rapid method reduces the delay between clinical suspicion and initiation of an appropriate treatment. However, the availability of a clinical strain is important to improve knowledge of circulating bacteria, to document case clusters, and to identify the sources of contamination. The source of contamination is unknown in most cases. The main contamination sources generating aerosols are water network systems and cooling towers. Thanks to the strengthening of clinical and environmental monitoring and to several guidelines, no epidemic has been reported in France since 2006. Despite these efforts, the number of LD cases has not decreased in recent years. It is essential that applied research continue to better understand the spatial and temporal dynamics of the disease and its characteristics (impact of environmental factors, sources of exposure, strains, host, etc.). Fundamental knowledge has been greatly improved (pathogenesis, immune mechanisms, etc.). The results of this research should help define new strategies for the diagnosis, prevention, and control to decrease the number of LD cases diagnosed every year.

  7. Women in physics in France

    SciTech Connect

    Pierron-Bohnes, Véronique

    2015-12-31

    We present six associations and entities working in France on issues of women in physics: the Women and Physics Commission, French Physical Society; Women in Nuclear (WiN) France; Women and Science Association; Mission for the Place of Women at CNRS; Parity, Diversity, and Women Network, CEA; and the Network of University Equality-Diversity Representatives.

  8. France acts on electronic cigarettes.

    PubMed

    Cahn, Zachary

    2013-11-01

    France is deciding how to regulate electronic cigarettes. I first consider the French approach and how it contrasts with other attempts at electronic cigarette regulation globally. Next, I critique the individual elements of the French proposal. The overall approach taken by France is a positive development, but banning indoor use appears unnecessary and banning advertising may be counterproductive.

  9. Dynamic study of yeast species and Saccharomyces cerevisiae strains during the spontaneous fermentations of Muscat blanc in Jingyang, China.

    PubMed

    Wang, Chunxiao; Liu, Yanlin

    2013-04-01

    The evolution of yeast species and Saccharomyces cerevisiae genotypes during spontaneous fermentations of Muscat blanc planted in 1957 in Jingyang region of China was followed in this study. Using a combination of colony morphology on Wallerstein Nutrient (WLN) medium, sequence analysis of the 26S rDNA D1/D2 domain and 5.8S-ITS-RFLP analysis, a total of 686 isolates were identified at the species level. The six species identified were S. cerevisiae, Hanseniaspora uvarum, Hanseniaspora opuntiae, Issatchenkia terricola, Pichia kudriavzevii (Issatchenkia orientalis) and Trichosporon coremiiforme. This is the first report of T. coremiiforme as an inhabitant of grape must. Three new colony morphologies on WLN medium and one new 5.8S-ITS-RFLP profile are described. Species of non-Saccharomyces, predominantly H. opuntiae, were found in early stages of fermentation. Subsequently, S. cerevisiae prevailed followed by large numbers of P. kudriavzevii that dominated at the end of fermentations. Six native genotypes of S. cerevisiae were determined by interdelta sequence analysis. Genotypes III and IV were predominant. As a first step in exploring untapped yeast resources of the region, this study is important for monitoring the yeast ecology in native fermentations and screening indigenous yeasts that will produce wines with regional characteristics.

  10. ASTER Images Mt. Usu Volcano

    NASA Technical Reports Server (NTRS)

    2000-01-01

    On April 3, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra Satellite captured this image of the erupting Mt. Usu volcano in Hokkaido, Japan. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER will image the Earth for the next 6 years to map and monitor the changing surface of our planet.

    This false color infrared image of Mt Usu volcano is dominated by Lake Toya, an ancient volcanic caldera. On the south shore is the active Usu volcano. On Friday, March 31, more than 11,000 people were evacuated by helicopter, truck and boat from the foot of Usu, that began erupting from the northwest flank, shooting debris and plumes of smoke streaked with blue lightning thousands of feet in the air. Although no lava gushed from the mountain, rocks and ash continued to fall after the eruption. The region was shaken by thousands of tremors before the eruption. People said they could taste grit from the ash that was spewed as high as 2,700 meters (8,850 ft) into the sky and fell to coat surrounding towns with ash. 'Mount Usu has had seven significant eruptions that we know of, and at no time has it ended quickly with only a small scale eruption,' said Yoshio Katsui, a professor at Hokkaido University. This was the seventh major eruption of Mount Usu in the past 300 years. Fifty people died when the volcano erupted in 1822, its worst known eruption.

    In the image, most of the land is covered by snow. Vegetation, appearing red in the false color composite, can be seen in the agricultural fields, and forests in the mountains. Mt. Usu is crossed by three dark streaks. These are the paths of ash deposits that rained out from eruption plumes two days earlier. The prevailing wind was from the northwest, carrying the ash away from the main city of Date. Ash deposited can be traced on the image as far away as 10 kilometers (16

  11. The role of MT2-MMP in cancer progression

    SciTech Connect

    Ito, Emiko; Yana, Ikuo; Fujita, Chisato; Irifune, Aiko; Takeda, Maki; Madachi, Ayako; Mori, Seiji; Hamada, Yoshinosuke; Kawaguchi, Naomasa; Matsuura, Nariaki

    2010-03-05

    The role of MT2-MMP in cancer progression remains to be elucidated in spite of many reports on MT1-MMP. Using a human fibrosarcoma cell, HT1080 and a human gastric cancer cell, TMK-1, endogenous expression of MT1-MMP or MT2-MMP was suppressed by siRNA induction to examine the influence of cancer progression in vitro and in vivo. In HT1080 cells, positive both in MT1-MMP and MT2-MMP, the migration as well as the invasion was impaired by MT1-MMP or MT2-MMP suppression. Also cell proliferation in three dimensional (3D) condition was inhibited by MT1-MMP or MT2-MMP suppression and tumor growth in the nude mice transplanted with tumor cells were reduced either MT1-MMP or MT2-MMP suppression with a prolongation of survival time in vivo. MT2-MMP suppression induces more inhibitory effects on 3D proliferation and in vivo tumor growth than MT1-MMP. On the other hand, TMK-1 cells, negative in MT1-MMP and MMP-2 but positive in MT2-MMP, all the migratory, invasive, and 3D proliferative activities in TMK-1 are decreased only by MT2-MMP suppression. These results indicate MT2-MMP might be involved in the cancer progression more than or equal to MT1-MMP independently of MMP-2 and MT1-MMP.

  12. Mt. Pinatubo, Phillippines - Perspective View

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The effects of the June 15, 1991, eruption of Mt. Pinatubo continue to affect the lives of people living near the volcano on the island of Luzon in the Philippines. The eruption produced a large amount of volcanic debris that was deposited on the flanks of the volcano as part of pyroclastic flows. This perspective view looking toward the east shows the western flank of the volcano where most of these pyroclastic flows were deposited.

    This debris consists of ash and boulders that mix with water after heavy rains to form volcanic mudflows called lahars. Lahars are moving rivers of concrete slurry that are highly erosive. They can sweep down existing river valleys, carving deep canyons where the slopes are steep, or depositing a mixture of fine ash and larger rocks on the gentler slopes. The deposits left from a lahar soon solidify into a material similar to concrete, but while they are moving, lahars are dynamic features, and in a single river valley the active channel may change locations within a few minutes or hours. These changes represent a significant natural hazard to local communities.

    The topographic data were collected by NASA's airborne imaging radar AIRSAR instrument on November 29, 1996. Colors are from the French SPOT satellite imaging data in both visible and infrared wavelengths collected in February 1996. Areas of vegetation appear red and areas without vegetation appear light blue. River valleys radiate out from the summit of the volcano (upper center). Since the eruption, lahars have stripped these valleys of any vegetation. The Pasig-Potrero River flows to the northeast off the summit in the upper right of the image.

    Scientists have been using airborne radar data collected by the AIRSAR instrument in their studies of the aftereffects of the Mt. Pinatubo eruption. AIRSAR collected imaging radar data over the volcano during a mission to the Pacific Rim region in late 1996 and on a follow-up mission to the area in late 2000. These data sets

  13. Chronic erosion in Wissant Bay coast, northern France - Causes and trials of management projects

    NASA Astrophysics Data System (ADS)

    Sedrati, M.; Anthony, E. J.

    2012-04-01

    Cape Gris Nez to the southwest and Cape Blanc Nez to the northeast limit's Wissant Bay. This extreme northern coast of France, facing the Dover Strait, is one of the most rapidly eroding sector of coast in France. Shoreline retreat has exceeded 250 m in the last fifty years in the central and western parts of the bay, while the eastern sector of the bay is now a zone of accretion, after being a sand-starved zone in the past, when the western sector was either stable or in accretion. The reasons for these changes are still not clear. They seem to involve interactions between a nearshore sand bank and the activity of current gyres related to the projecting headland of Cape Gris Nez, beach rotation processes and human activities, notably past aggregate extraction from the nearshore sand bank which acted hitherto as both a dissipater of incident storm wave energy and as a coastal sand source. The aim of this paper to contribute to the understanding of these long-term changes and investigate the mechanisms of this mildly embayed coast evolution. To this end, 10-years of topographic profile data throughout the bay were analysed and confronted with offshore wave data. This analysis complements a previous analytical effort that determined gross rates of annual shoreline retreat by time slices of several decades from the careful interpretation of long series of ortho-rectified aerial photographs. The overall data suggest chronic sand bleeding from the western sector of the beach and longshore transport to the east, within a framework of what appears to be an ongoing beach rotation process within a dominant longshore sediment transport cell between the headland of Cape Gris Nez and the bold chalk cliffs of Cape Blanc Nez. Retreat of the beach-dune barrier in the western sector of Wissant Bay poses a threat in the coming years as there is a likelihood of storm breaching of the narrow dune barrier. Face to this critical situation, a proper management strategy involving a good

  14. Molecular cloning and pharmacological characterization of rat melatonin MT1 and MT2 receptors.

    PubMed

    Audinot, Valérie; Bonnaud, Anne; Grandcolas, Line; Rodriguez, Marianne; Nagel, Nadine; Galizzi, Jean-Pierre; Balik, Ales; Messager, Sophie; Hazlerigg, David G; Barrett, Perry; Delagrange, Philippe; Boutin, Jean A

    2008-05-15

    In order to interpret the effects of melatonin ligands in rats, we need to determine their activity at the receptor subtype level in the corresponding species. Thus, the rat melatonin rMT(1) receptor was cloned using DNA fragments for exon 1 and 2 amplified from rat genomic DNA followed by screening of a rat genomic library for the full length exon sequences. The rat rMT(2) receptor subtype was cloned in a similar manner with the exception of exon 1 which was identified by screening a rat genomic library with exon 1 of the human hMT(2) receptor. The coding region of these receptors translates proteins of 353 and 364 amino acids, respectively, for rMT(1) and rMT(2). A 55% homology was observed between both rat isoforms. The entire contiguous rat MT(1) and MT(2) receptor coding sequences were cloned, stably expressed in CHO cells and characterized in binding assay using 2-[(125)I]-Iodomelatonin. The dissociation constants (K(d)) for rMT(1) and rMT(2) were 42 and 130 pM, respectively. Chemically diverse compounds previously characterized at human MT(1) and MT(2) receptors were evaluated at rMT(1) and rMT(2) receptors, for their binding affinity and functionality in [(35)S]-GTPgammaS binding assay. Some, but not all, compounds shared a similar binding affinity and functionality at both rat and human corresponding subtypes. A different pharmacological profile of the MT(1) subtype has also been observed previously between human and ovine species. These in vitro results obtained with the rat melatonin receptors are thus of importance to understand the physiological roles of each subtype in animal models.

  15. [Nurse anesthetist in France].

    PubMed

    Mizuno, Ju; Yann, Douchy; De Almeida, Sylvie; Deckert, Christine; Gauss, Tobias; Bonneville, Claire Tae; Merckx, Paul; Mantz, Jean

    2006-12-01

    We present the system of nurse anesthetist (Infirmier Anesthésiste Diplômé d'Etat: IADE) in France to the community of Japanese anesthesiologists. This French system with 70 years' history is older than the Japan Society of Anesthesiologists itself. There are 7000 nurse anesthetists in France now and the number of nurse anesthetists increases by 450-500 each year. Training to become a nurse anesthetist requires at least two years' experience as a general nurse and the general nurse must pass an examination after two years' special training in an anesthetistic nurse school to acquire the national certification. The nurse anesthetist's profession is regulated by French law. They work in a team with certified anesthesiologists. They can perform many kinds of anesthetic tasks including tracheal intubation and insertion of arterial catheter under the responsibility and supervision of certified anesthesiologists. The nurse anesthetists are not allowed to perform spinal, epidural, conduction and local anesthesia, although they can maintain these anesthesia and control these methods, e.g., by injecting local anesthetic agents through epidural catheter, following a specified prescription. The nurse anesthetists are not allowed to insert central venous and pulmonary artery catheters, although they can manage them. They are allowed to administer inhalation anesthetic agents, and inject venous anesthetic agents, muscle relaxants, their antagonists, and opioids by their own initiatives, but the decision for the use of catecholamine and emergency drugs is reserved to certified anesthesiologists. The nurse anesthetists perform other tasks preparing and checking anesthetic agents and equipment such as anesthetic machine, monitor, and defibrillator everyday, and sometimes use autologous blood recovery systems. The relationship between the certified anesthesiologist and the nurse anesthetist is marked by mutual respect, confidence and cooperation at each step of the anesthetic

  16. The "Casa" of Sevres, France.

    ERIC Educational Resources Information Center

    Waltuch, Margot

    1996-01-01

    Discusses the author's teaching experiences during the 1930s at "La Maison des Enfants," a Montessori school in Sevres, France. Provides photographs and descriptions of the school day, outdoor activities, gardening, cooking and eating, practical activities, and creative activities. (MDM)

  17. mtDNA analysis reveals a major late Paleolithic population expansion from southwestern to northeastern Europe.

    PubMed Central

    Torroni, A; Bandelt, H J; D'Urbano, L; Lahermo, P; Moral, P; Sellitto, D; Rengo, C; Forster, P; Savontaus, M L; Bonné-Tamir, B; Scozzari, R

    1998-01-01

    mtDNA sequence variation was studied in 419 individuals from nine Eurasian populations, by high-resolution RFLP analysis, and it was followed by sequencing of the control region of a subset of these mtDNAs and a detailed survey of previously published data from numerous other European populations. This analysis revealed that a major Paleolithic population expansion from the "Atlantic zone" (southwestern Europe) occurred 10,000-15,000 years ago, after the Last Glacial Maximum. As an mtDNA marker for this expansion we identified haplogroup V, an autochthonous European haplogroup, which most likely originated in the northern Iberian peninsula or southwestern France at about the time of the Younger Dryas. Its sister haplogroup, H, which is distributed throughout the entire range of Caucasoid populations and which originated in the Near East approximately 25,000-30,000 years ago, also took part in this expansion, thus rendering it by far the most frequent (40%-60%) haplogroup in western Europe. Subsequent migrations after the Younger Dryas eventually carried those "Atlantic" mtDNAs into central and northern Europe. This scenario, already implied by archaeological records, is given overwhelming support from both the distribution of the autochthonous European Y chromosome type 15, as detected by the probes 49a/f, and the synthetic maps of nuclear data. PMID:9545392

  18. Chemical and Histochemical Analysis of ‘Quatre Saisons Blanc Mousseux’, a Moss Rose of the Rosa × damascena Group

    PubMed Central

    CAISSARD, JEAN-CLAUDE; BERGOUGNOUX, VÉRONIQUE; MARTIN, MAGALI; MAURIAT, MÉLANIE; BAUDINO, SYLVIE

    2006-01-01

    • Background and Aims Moss roses are old garden roses covered with a mossy growth on flower pedicel and calyx. This moss releases a pine-scented oleoresin that is very sticky and odoriferous. Rosa × centifolia ‘muscosa’ was the first moss rose to be obtained by bud-mutation but, interestingly, R. × damascena ‘Quatre Saisons Blanc Mousseux’ was the first repeat-blooming cultivar, thus interesting breeders. In the present study, the anatomy of these sports (i.e. bud-mutations) is characterized and the volatile organic compounds (VOCs) produced by the moss versus the petals are identified. They are compared between the two lines and their respective parents. • Methods Anatomy of the moss is studied by environmental scanning electron microscopy and histochemical light microscopy. Sudan Red IV and Fluorol Yellow 088 are used to detect lipids, and 1-naphthol reaction with N,N-dimethyl-p-phenylenediamine to detect terpenes (Nadi reaction). Head-space or solid/liquid extraction followed by gas chromatography and mass spectrometry are used to identify VOCs in moss, trichomes and petals. • Key Results Moss of the two cultivars has the same structure with trichomes on other trichomes but not exactly the same VOCs. These VOCs are specific to the moss, with lots of terpenes. An identical VOC composition is found in leaves but not in petals. They are nearly the same in the moss mutants and in the respective wild types. • Conclusions Sepals of moss roses and their parents have a specific VOC pattern, different from that of the petals. The moss corresponds to a heterochronic mutation with trichomes developing on other trichomes. Such a mutation has probably appeared twice and independently in the two lines. PMID:16344264

  19. Volcanic earthquake swarms at Mt. Erebus, Antarctica

    NASA Astrophysics Data System (ADS)

    Kaminuma, Katsutada; Ueki, Sadato; Juergen, Kienle

    1985-04-01

    Mount Erebus is an active volcano in Antarctica located on Ross Island. A convecting lava lake occupies the summit crater of Mt. Erebus. Since December 1980 the seismic activity of Mt. Erebus has been continuously monitored using a radio-telemetered network of six seismic stations. The seismic activity observed by the Ross Island network during the 1982-1983 field season shows that: (1)Strombolian eruptions occur frequently at the Erebus summit lava lake at rates of 2-5 per day; (2)centrally located earthquakes map out a nearly vertical, narrow conduit system beneath the lava lake; (3)there are other source regions of seismicity on Ross Island, well removed from Mt. Erebus proper. An intense earthquake swarm recorded in October 1982 near Abbott Peak, 10 km northwest of the summit of Mt. Erebus, and volcanic tremor accompanying the swarm, may have been associated with new dike emplacement at depth.

  20. 78 FR 44187 - Montana Disaster # MT-00079

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Montana Disaster MT-00079 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY... have been determined to be adversely affected by the disaster: Primary Counties: Blaine,...

  1. Goldfish (Carassius auratus) matching geometric and featural cues: a reinterpretation of some of the data of Vargas, López, Salas, and Thinus-Blanc (2004).

    PubMed

    Cheng, Ken

    2005-11-01

    Vargas, López, Salas, and Thinus-Blanc showed that goldfish (Carassius auratus) can use both geometric and featural cues in relocating a target corner in a rectangular enclosure. When featural cues (arrangement of striped walls) were put in conflict with geometric cues, results differed according to target location during training. Vargas, López, et al. explained the results of their cue conflict in terms of 2 different strategies: mapping and cue guidance. I provide an alternative, more parsimonious interpretation in which the same strategy of attempting to match as many cues as possible applies to both cases.

  2. High morphogenic activity in the permafrost-affected rock walls of the Mont Blanc massif during the 2015 summer heat wave

    NASA Astrophysics Data System (ADS)

    Ravanel, Ludovic; Magnin, Florence; Deline, Philip

    2016-04-01

    In order to test the geomorphological hypothesis on the link between permafrost degradation and rock wall destabilisation, we survey all the rockfalls that occur in the central part of the Mont-Blanc massif using a network of observers since 2007. 511 rockfalls (100 < V < 45,000 m3) have been documented, year 2015 included. Between 2007 and 2014, the average number of destabilizations was 44 (from 17 in 2014 with a cold summer to 72 in 2009 with a relatively hot summer). In 2015, 160 events were recorded i.e. 4 times more than the annual average of the previous years. That makes the year 2015 similar to 2003 that was characterized by its summer heatwave triggering 152 rockfalls in the area currently covered by the network of observers, as shown by the analysis of a SPOT-5 image. Observations of 2015 are discussed and crossed with a statistical model of the Mean Annual Rock Surface Temperature (MARST) for the 1961-1990 period, implemented on a 4-m-resolution DEM of the Mont Blanc massif, and temperature measurements in three 10-m-deep boreholes at the Aiguille du Midi (3842 m a.s.l.), where the summer 2015 active layers have been the thickest since the start of measurements in 2009 (e.g. 3.6 m in the NE face against 2.9 m in average during the previous years). Before 2015, 90 % of the inventoried rockfalls occurred in areas where MARST is in the range -5 to 1°C, whereas only 50 % of the whole rock wall area above 2000 m a.s.l. covers this temperature range. With an air 0°C isotherm which sometimes exceeded the summit of Mont Blanc (4809 m a.s.l.) during the 2015 Summer, conditions were particularly unfavorable for mountaineering. Numerous rescues were carried out to climbers technically blocked by uncommon conditions or injured by rockfalls. On the normal route to the summit of Mont Blanc, two administrative closures of the Goûter hut (3835 m a.s.l.) were necessary to prevent climbers from the huge risk of rockfalls in the access couloir, known for its rockfall

  3. Correlations of low-energy pulses and muons recorded by the LSD detector near Mont Blanc from February 10 to July 1, 1987

    NASA Astrophysics Data System (ADS)

    Dadykin, V. L.; Zatsepin, G. T.; Korol'Kova, E. V.; Korchagin, P. V.; Kudriavtsev, V. A.

    1991-04-01

    Observation data obtained by the LSD underground detector near Mont Blanc over the period February 10 - July 1, 1987, are analyzed for possible time correlations between all events with an energy over 5 MeV detected during this period. Nine pairs of correlated pulses (muons and low-energy pulses with a time interval of 2 s) are identified during the period from 5:42 to 10:13 UT on February 23, 1987 (i.e., around the time of the optical burst CH 1987A). The result indicates a possible relation between the time correlation of the pulses and the burst.

  4. SN1987A: correlation between the data recorded by the Mont Blanc neutrino detector and by the Maryland and Rome gravitational wave antennas.

    NASA Astrophysics Data System (ADS)

    Pallottino, G. V.

    The author reports the analysis of gravitational wave and neutrino detectors over a period of 18 hours that includes the Mont Blanc 5 neutrino burst time. There is statistical evidence for correlations during a period of about two hours, centered on the 5 neutrino burst: the effect is mainly due to a dozen of large amplitude Maryland and Rome events. The interpretation of these events as due to gravitational radiation from SN1987A should be rejected, according to the standard theory of the cross-section of g.w. detectors, since it would imply an emission of energy too large by a factor of about 104.

  5. Distant Mt. Fuji, Island of Honshu Japan

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This distant view of Mt. Fuji, on the main home island of Honshu, Japan (34.0N, 139.0E) was taken from about 450 miles to the south. Evan at that great distance, the majestic and inspiring Mt. Fuji is still plainly visible and easily recognized as a world renowned symbol of Japan. The snow capped extinct volcano lies just a few miles south of Tokyo.

  6. The Italian drilling project of the Mont Blanc road tunnel in the late fifties: an example of no geological care and lack of ethics in carrying out a big work.

    NASA Astrophysics Data System (ADS)

    Gosso, Guido; Croce, Giuseppe; Matteucci, Ruggero; Peppoloni, Silvia; Piacente, Sandra; Wasowski, Janusz

    2013-04-01

    In the first decade after the Second World War Italy was rushing to recover a positive role among European countries; basic needs as road communications with European neighbours became main priorities. The necessity of a rapid connection with South-eastern France, a subject already debated between the two nations over more than 50 years, appeared then on first line; the two countries convened on a joint investment for the construction of a tunnel across the international border of Mont Blanc, along the shortest track between Courmayeur and Chamonix. The political agreements were in favour of the quickest start of the drilling operations and such obligation imposed on the Italian side an impoverishment of the project content, specially concerning geological issues. No surveys were performed on fracture systems, cataclastic zones and faults, on the few rock ridges standing above the tunnel line and outcropping through thick talus cones, moraines, ice tongues and their related ice plateaus. Metasediments, migmatites and poorly foliated granites were to be drilled. Three Italian academics were allowed by the drilling company to track the working progress and collect rocks for comparison with other Alpine types; they mapped the lithology and the fault zonesall along the freshly excavated tunnel; the results of such survey appeared after the end of works. Geologists from Florence University published the surface granite faulting pattern 20 years after the road tunnel became operative. Such geological cares could have located the risky zones in time for the tunnel project, mitigating the catastrophic effects of sudden drainage of subglacial water from the Vallée Blanche ice plateau (Ghiacciaio del Gigante) at progression 3800m, that caused dramatic accidents and affected negatively the economy of the drilling. Also the wallrock temperature drops, measured during the drill, should have warned the company management on the location of dangerous fracture zones. Anxiety of

  7. 44 CFR 15.3 - Access to Mt. Weather.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Access to Mt. Weather. 15.3... HOMELAND SECURITY GENERAL CONDUCT AT THE MT. WEATHER EMERGENCY ASSISTANCE CENTER AND AT THE NATIONAL EMERGENCY TRAINING CENTER § 15.3 Access to Mt. Weather. Mt. Weather contains classified material and...

  8. 44 CFR 15.3 - Access to Mt. Weather.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Access to Mt. Weather. 15.3... HOMELAND SECURITY GENERAL CONDUCT AT THE MT. WEATHER EMERGENCY ASSISTANCE CENTER AND AT THE NATIONAL EMERGENCY TRAINING CENTER § 15.3 Access to Mt. Weather. Mt. Weather contains classified material and...

  9. 44 CFR 15.3 - Access to Mt. Weather.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Access to Mt. Weather. 15.3... HOMELAND SECURITY GENERAL CONDUCT AT THE MT. WEATHER EMERGENCY ASSISTANCE CENTER AND AT THE NATIONAL EMERGENCY TRAINING CENTER § 15.3 Access to Mt. Weather. Mt. Weather contains classified material and...

  10. 44 CFR 15.3 - Access to Mt. Weather.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Access to Mt. Weather. 15.3... HOMELAND SECURITY GENERAL CONDUCT AT THE MT. WEATHER EMERGENCY ASSISTANCE CENTER AND AT THE NATIONAL EMERGENCY TRAINING CENTER § 15.3 Access to Mt. Weather. Mt. Weather contains classified material and...

  11. 44 CFR 15.3 - Access to Mt. Weather.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Access to Mt. Weather. 15.3... HOMELAND SECURITY GENERAL CONDUCT AT THE MT. WEATHER EMERGENCY ASSISTANCE CENTER AND AT THE NATIONAL EMERGENCY TRAINING CENTER § 15.3 Access to Mt. Weather. Mt. Weather contains classified material and...

  12. 25 years (1981-2005) of equilibrium-line altitude and mass-balance reconstruction on Glacier Blanc, French Alps, using remote-sensing methods and meteorological data

    NASA Astrophysics Data System (ADS)

    Rabatel, Antoine; Dedieu, Jean-Pierre; Thibert, Emmanuel; Letréguilly, Anne; Vincent, Christian

    Annual equilibrium-line altitude (ELA) and surface mass balance of Glacier Blanc, Ecrins region, French Alps, were reconstructed from a 25 year time series of satellite images (1981-2005). The remote-sensing method used was based on identification of the snowline, which is easy to discern on optical satellite images taken at the end of the ablation season. In addition, surface mass balances at the ELA were reconstructed for the same period using meteorological data from three nearby weather stations. A comparison of the two types of series reveals a correlation of r > 0.67 at the 0.01 level of significance. Furthermore, the surface mass balances obtained from remote-sensing data are consistent with those obtained from field measurements on five other French glaciers (r = 0.76, p < 0.01). Also consistent for Glacier Blanc is the total mass loss (10.8 m w.e.) over the studied period. However, the surface mass balances obtained with the remote-sensing method show lower interannual variability. Given that the remote-sensing method is based on changes in the ELA, this difference probably results from the lower sensitivity of the surface mass balance to climate parameters at the ELA.

  13. Impact of oxygen dissolved at bottling and transmitted through closures on the composition and sensory properties of a Sauvignon Blanc wine during bottle storage.

    PubMed

    Lopes, Paulo; Silva, Maria A; Pons, Alexandre; Tominaga, Takatoshi; Lavigne, Valérie; Saucier, Cédric; Darriet, Philippe; Teissedre, Pierre-Louis; Dubourdieu, Denis

    2009-11-11

    This work outlines the results from an investigation to determine the effect of the oxygen dissolved at bottling and the specific oxygen barrier properties of commercially available closures on the composition, color and sensory properties of a Bordeaux Sauvignon Blanc wine during two years of storage. The importance of oxygen for wine development after bottling was also assessed using an airtight bottle ampule. Wines were assessed for the antioxidants (SO(2) and ascorbic acid), varietal thiols (4-mercapto-4-methylpentan-2-one, 3-mercaptohexan-1-ol), hydrogen sulfide and sotolon content, and color throughout 24 months of storage. In addition, the aroma and palate properties of wines were also assessed. The combination of oxygen dissolved at bottling and the oxygen transferred through closures has a significant effect on Sauvignon Blanc development after bottling. Wines highly exposed to oxygen at bottling and those sealed with a synthetic, Nomacorc classic closure, highly permeable to oxygen, were relatively oxidized in aroma, brown in color, and low in antioxidants and volatile compounds compared to wines sealed with other closures. Conversely, wines sealed under more airtight conditions, bottle ampule and screw cap Saran-tin, have the slowest rate of browning, and displayed the greatest contents of antioxidants and varietal thiols, but also high levels of H(2)S, which were responsible for the reduced dominating character found in these wines, while wines sealed with cork stoppers and screw cap Saranex presented negligible reduced and oxidized characters.

  14. 3D Detection, Quantification and Correlation of Slope Failures with Geologic Structure in the Mont Blanc massif

    NASA Astrophysics Data System (ADS)

    Allan, Mark; Dunning, Stuart; Lim, Michael; Woodward, John

    2016-04-01

    A thorough understanding of supply from landslides and knowledge of their spatial distribution is of fundamental importance to high-mountain sediment budgets. Advances in 3D data acquisition techniques are heralding new opportunities to create high-resolution topographic models to aid our understanding of landscape change through time. In this study, we use a Structure-from-Motion Multi-View Stereo (SfM-MVS) approach to detect and quantify slope failures at selected sites in the Mont Blanc massif. Past and present glaciations along with its topographical characteristics have resulted in a high rate of geomorphological activity within the range. Data for SfM-MVS processing were captured across variable temporal scales to examine short-term (daily), seasonal and annual change from terrestrial, Unmanned Aerial Vehicle (UAV) and helicopter perspectives. Variable spatial scales were also examined ranging from small focussed slopes (~0.01 km2) to large valley-scale surveys (~3 km2). Alignment and registration were conducted using a series of Ground Control Points (GCPs) across the surveyed slope at various heights and slope aspects. GCPs were also used to optimise data and reduce non-linear distortions. 3D differencing was performed using a multiscale model-to-model comparison algorithm (M3C2) which uses variable thresholding across each slope based on local surface roughness and model alignment quality. Detected change was correlated with local slope structure and 3D discontinuity analysis was undertaken using a plane-detection and clustering approach (DSE). Computation of joint spacing was performed using the classified data and normal distances. Structural analysis allowed us to assign a Slope Mass Rating (SMR) and assess the stability of each slope relative to the detected change and determine likely failure modes. We demonstrate an entirely 3D workflow which preserves the complexity of alpine slope topography to compute volumetric loss using a variable threshold. A

  15. Rare earth and trace element mobility in mid-crustal shear zones: insights from the Mont Blanc Massif (Western Alps)

    NASA Astrophysics Data System (ADS)

    Rolland, Yann; Cox, Stephen; Boullier, Anne-Marie; Pennacchioni, Giorgio; Mancktelow, Neil

    2003-09-01

    The behaviour of rare earth elements (REE) during fluid-rock interaction in mid-crustal shear zones has received little attention, despite their potential for mass balance calculation and isotopic tracing during deformation. In this study, several cases of large REE mobility during Alpine fluid-driven shear zone development in the pre-Alpine granitic basement of the Mont Blanc Massif are considered. On a regional scale, the undeformed granite compositions range within 5 wt% SiO 2 (70.5-75.3 wt%) and magmatic chemical variations are of the order of 10-20%, ascribed to minor effects of crystal fractionation. Major and trace element mobility observed in shear zones largely exceeds these initial variations. Shear zones developed a range of mineral assemblages as a result of shearing at mid-crustal depths (at ˜0.5 GPa, 400°C). Five main shear zone assemblages involve muscovite, chlorite, epidote, actinolite and calcite, respectively, as major phases. In most cases, selective enrichments of light or heavy REE (and Y, Ta, Hf) are observed. REE mobility is unrelated to deformation style (cataclastic, mylonitic), the intensity of strain, and to the shear zone's major metamorphic mineral assemblages. Instead, the changes in REE concentrations are ascribed to the alteration of pre-existing magmatic REE-bearing minerals during deformation-related fluid-rock interaction and to the syntectonic precipitation of metamorphic REE-bearing minerals (mainly monazite, bastnäsite, aeschynite and tombarthite). Minor proportions (<2%) of these accessory phases, with grain sizes mostly <20 μm, account for enrichments of up to 5:1 compared to the initial granite whole-rock REE budget. The stability of the REE phases appears to be largely dependent on the altering fluid composition. REE mobility is ascribed to changes in pH and to the availability of CO 32-, PO 42-, and SO 42-ligands in the fluid. Such processes are likely to influence the mobility of REE, Y, Hf and Ta in shear zones.

  16. Beginning of Viniculture in France

    NASA Technical Reports Server (NTRS)

    McGovern, Patrick E.; Luley, Benjamin P.; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P.; Smith, Karen F.; Hall, Gretchen R.; Davidson, Theodore; Henkin, Joshua M.

    2013-01-01

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport.

  17. Beginning of viniculture in France.

    PubMed

    McGovern, Patrick E; Luley, Benjamin P; Rovira, Nuria; Mirzoian, Armen; Callahan, Michael P; Smith, Karen E; Hall, Gretchen R; Davidson, Theodore; Henkin, Joshua M

    2013-06-18

    Chemical analyses of ancient organic compounds absorbed into the pottery fabrics of imported Etruscan amphoras (ca. 500-475 B.C.) and into a limestone pressing platform (ca. 425-400 B.C.) at the ancient coastal port site of Lattara in southern France provide the earliest biomolecular archaeological evidence for grape wine and viniculture from this country, which is crucial to the later history of wine in Europe and the rest of the world. The data support the hypothesis that export of wine by ship from Etruria in central Italy to southern Mediterranean France fueled an ever-growing market and interest in wine there, which, in turn, as evidenced by the winepress, led to transplantation of the Eurasian grapevine and the beginning of a Celtic industry in France. Herbal and pine resin additives to the Etruscan wine point to the medicinal role of wine in antiquity, as well as a means of preserving it during marine transport.

  18. Pyemotes ventricosus Dermatitis, Southeastern France

    PubMed Central

    Blanc-Amrane, Véronique; Bahadoran, Philippe; Caumes, Eric; Marty, Pierre; Lazar, Mariléna; Boissy, Christian; Desruelles, François; Izri, Arezki; Ortonne, Jean-Paul; Counillon, Evelyne; Chosidow, Olivier; Delaunay, Pascal

    2008-01-01

    We investigated 42 patients who had unusual pruritic dermatitis associated with a specific clinical sign (comet sign) in 23 houses in southeastern France from May through September 2007. Pyemotes ventricosus, a parasite of the furniture beetle Anobium punctatum, was the cause of this condition. PMID:18976564

  19. Earthworm Lumbricus rubellus MT-2: Metal Binding and Protein Folding of a True Cadmium-MT

    PubMed Central

    Kowald, Gregory R.; Stürzenbaum, Stephen R.; Blindauer, Claudia A.

    2016-01-01

    Earthworms express, as most animals, metallothioneins (MTs)—small, cysteine-rich proteins that bind d10 metal ions (Zn(II), Cd(II), or Cu(I)) in clusters. Three MT homologues are known for Lumbricus rubellus, the common red earthworm, one of which, wMT-2, is strongly induced by exposure of worms to cadmium. This study concerns composition, metal binding affinity and metal-dependent protein folding of wMT-2 expressed recombinantly and purified in the presence of Cd(II) and Zn(II). Crucially, whilst a single Cd7wMT-2 species was isolated from wMT-2-expressing E. coli cultures supplemented with Cd(II), expressions in the presence of Zn(II) yielded mixtures. The average affinities of wMT-2 determined for either Cd(II) or Zn(II) are both within normal ranges for MTs; hence, differential behaviour cannot be explained on the basis of overall affinity. Therefore, the protein folding properties of Cd- and Zn-wMT-2 were compared by 1H NMR spectroscopy. This comparison revealed that the protein fold is better defined in the presence of cadmium than in the presence of zinc. These differences in folding and dynamics may be at the root of the differential behaviour of the cadmium- and zinc-bound protein in vitro, and may ultimately also help in distinguishing zinc and cadmium in the earthworm in vivo. PMID:26742040

  20. Earthworm Lumbricus rubellus MT-2: Metal Binding and Protein Folding of a True Cadmium-MT.

    PubMed

    Kowald, Gregory R; Stürzenbaum, Stephen R; Blindauer, Claudia A

    2016-01-05

    Earthworms express, as most animals, metallothioneins (MTs)-small, cysteine-rich proteins that bind d(10) metal ions (Zn(II), Cd(II), or Cu(I)) in clusters. Three MT homologues are known for Lumbricus rubellus, the common red earthworm, one of which, wMT-2, is strongly induced by exposure of worms to cadmium. This study concerns composition, metal binding affinity and metal-dependent protein folding of wMT-2 expressed recombinantly and purified in the presence of Cd(II) and Zn(II). Crucially, whilst a single Cd₇wMT-2 species was isolated from wMT-2-expressing E. coli cultures supplemented with Cd(II), expressions in the presence of Zn(II) yielded mixtures. The average affinities of wMT-2 determined for either Cd(II) or Zn(II) are both within normal ranges for MTs; hence, differential behaviour cannot be explained on the basis of overall affinity. Therefore, the protein folding properties of Cd- and Zn-wMT-2 were compared by ¹H NMR spectroscopy. This comparison revealed that the protein fold is better defined in the presence of cadmium than in the presence of zinc. These differences in folding and dynamics may be at the root of the differential behaviour of the cadmium- and zinc-bound protein in vitro, and may ultimately also help in distinguishing zinc and cadmium in the earthworm in vivo.

  1. 77 FR 47907 - Montana Disaster #MT-00067

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... ADMINISTRATION Montana Disaster MT-00067 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of MONTANA dated 08/02/2012. Incident: Ash Creek Fire. Incident Period: 06/25/2012 through 07/22/2012. Effective Date:...

  2. 77 FR 48198 - Montana Disaster #MT-00068

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... ADMINISTRATION Montana Disaster MT-00068 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of Montana dated 08/06/2012. Incident: Dahl Fire. Incident Period: 06/26/2012 through 07/06/2012. Effective Date:...

  3. Bruce Medalists at the Mt. Wilson Observatory

    NASA Astrophysics Data System (ADS)

    Tenn, J. S.

    2004-12-01

    The institution which succeeded the Mt. Wilson Station of Yerkes Observatory in 1904 has had six names and three sites. From 1948-1980 it was united with Caltech's Palomar Observatory, and since then its main observatory has been in Chile, though still headquartered on Santa Barbara Street in Pasadena. For more than half of the twentieth century it was the leading observatory in the world. One bit of evidence for this is the amazing number of its staff members awarded the Bruce Medal. The Catherine Wolfe Bruce Gold Medal of the Astronomical Society of the Pacific has been awarded for lifetime contributions to astronomy since 1898. It is an international award. It wasn't until 1963 that the number of medalists who had worked primarily in the United States reached half the total. Yet fourteen of the first 87 medalists spent most of their careers at Mt. Wilson, including the period when it was Mt. Wilson and Palomar, and another three were Caltech observers who used the telescopes of the jointly operated observatory. Several more medalists made substantial use of the telescopes on Mt. Wilson and Palomar Mountain. We will discuss highlights of the careers of a number of these distinguished astronomers: directors George Ellery Hale, Walter Adams, Ira Bowen, and Horace Babcock; solar observer and satellite discoverer Seth Nicholson; instrument builder Harold Babcock; galactic and cosmological observers Frederick Seares, Edwin Hubble, Walter Baade, Rudolph Minkowski, and Allan Sandage; and spectroscopists Paul Merrill, Alfred Joy, Olin Wilson, Jesse Greenstein, Maarten Schmidt, and Wallace Sargent. We will touch briefly on others who used Mt. Wilson and/or Palomar, including Harlow Shapley, Joel Stebbins, Charlotte Moore Sitterly, Donald Osterbrock, and Albert Whitford.

  4. Surface exposure dating with cosmogenic 10Be of Late Holocene rock avalanches onto glaciers in the Mont Blanc massif, Italy

    NASA Astrophysics Data System (ADS)

    Deline, Philip; Akçar, Naki; Ivy-Ochs, Susan; Kubik, Peter W.

    2013-04-01

    Rock avalanching represents a potential high risk for growing infrastructure and people living in high mountain areas. This hazardous process is due to steep slopes, high relief, intensive rock fracturing, seismicity, paraglacial control, periglacial climatic conditions and the presence and interaction of snow, glaciers, and permafrost. The timing of rock avalanche recurrence intervals and the recognition of their spatial extension are essential. Very steep and elevated slopes on the Italian flank of the Mont Blanc massif are prone to rock avalanches (RAs) which travel onto glaciers. Whereas small RAs occurred in the Glacier du Miage basin during the 20th Century (the latest in July 2012), large RAs (volume > 1 M m3) travelled repeatedly onto Glaciers de Triolet, Frébouge, and la Brenva during the late Holocene The nature of the granitic deposit which largely overlaps the bottom of the upper Val Ferret over 2 km has been discussed since the 19th century. This extensive deposit was attributed to either glacial, or a September 12th 1717 AD rock avalanche, or a complex mixture of glacial, earlier RA and 1717 RA origin. Surface exposure dating of 16 boulders of the deposit shows that the 1717 RA, covering the whole upper Ferret valley floor, was one of the largest late Holocene RAs of the Alps, with a rock volume of 10-15 M m3 and a likely similar volume of glacier ice travelling more than 7 km downvalley. Two main RA deposits are lying downstream of the Glacier de Frébouge: a sheet of granite boulders with an open-work structure covers the south side of the Val Ferret, which ran > 100 m up the opposite metasedimentary side of the valley; a smaller RA deposit is located at the south and east margins of the large Frébouge polygenic fan. Surface exposure dating of 7 granite boulders of these deposits could in particular confirm whether the larger RA occurred sometime between 991 and 1154 AD, as suggested by a radiocarbon-dated piece of wood. Large RAs (volume > 2 M m3

  5. Geomatics techniques applied to time series of aerial images for multitemporal geomorphological analysis of the Miage Glacier (Mont Blanc).

    NASA Astrophysics Data System (ADS)

    Perotti, Luigi; Carletti, Roberto; Giardino, Marco; Mortara, Giovanni

    2010-05-01

    The Miage glacier is the major one in the Italian side of the Mont Blanc Massif, the third by area and the first by longitudinal extent among Italian glaciers. It is a typical debris covered glacier, since the end of the L.I.A. The debris coverage reduces ablation, allowing a relative stability of the glacier terminus, which is characterized by a wide and articulated moraine apparatus. For its conservative landforms, the Miage Glacier has a great importance for the analysis of the geomorphological response to recent climatic changes. Thanks to an organized existing archive of multitemporal aerial images (1935 to present) a photogrammetric approach has been applied to detect recent geomorphological changes in the Miage glacial basin. The research team provided: a) to digitize all the available images (still in analogic form) through photogrammetric scanners (very low image distortions devices) taking care of correctly defining the resolution of the acquisition compared to the scale mapping images are suitable for; b) to import digitized images into an appropriate digital photogrammetry software environment; c) to manage images in order, where possible, to carried out the stereo models orientation necessary for 3D navigation and plotting of critical geometric features of the glacier. Recognized geometric feature, referring to different periods, can be transferred to vector layers and imported in a GIS for further comparisons and investigations; d) to produce multi-temporal Digital Elevation Models for glacier volume changes; e) to perform orthoprojection of such images to obtain multitemporal orthoimages useful for areal an planar terrain evaluation and thematic analysis; f) to evaluate both planimetric positioning and height determination accuracies reachable through the photogrammetric process. Users have to known reliability of the measures they can do over such products. This can drive them to define the applicable field of this approach and this can help them to

  6. Rock falls in high-alpine rock walls quantified by terrestrial lidar measurements: A case study in the Mont Blanc area

    NASA Astrophysics Data System (ADS)

    Rabatel, Antoine; Deline, Philip; Jaillet, Stéphane; Ravanel, Ludovic

    2008-05-01

    The global warming observed in recent decades and its future increase may affect permafrost distribution on high-mountain faces with consequences for their stability. In this paper, we show that rock falls from high-alpine rock walls can be computed with a decimetre-resolution using lidar measurements. A laser scanner was used to create point clouds and triangulated irregular network models on the east face of the Tour Ronde at 3792 m asl (Mont Blanc massif). Comparison of the models realised from measurements of July 2005 and July 2006 enabled quantification of rock falls with reduced uncertainty. The volume of rock fall reached a total of 536 m3 in the scanned area, which matches an erosion rate of 8.4 mm yr-1. This rate slightly higher to the ones reported in former studies enable to assume that this rock fall may be the consequence of the permafrost degradation in this rock face.

  7. Melatonin MT1 and MT2 Receptors in the Ram Reproductive Tract

    PubMed Central

    González-Arto, Marta; Aguilar, David; Gaspar-Torrubia, Elena; Gallego, Margarita; Carvajal-Serna, Melissa; Herrera-Marcos, Luis V.; Serrano-Blesa, Edith; Hamilton, Thais Rose dos Santos; Pérez-Pé, Rosaura; Muiño-Blanco, Teresa; Cebrián-Pérez, José A.; Casao, Adriana

    2017-01-01

    Some melatonin functions in mammals are exerted through MT1 and MT2 receptors. However, there are no reports of their presence in the reproductive tract of the ram, a seasonal species. Thus, we have investigated their existence in the ram testis, epididymis, accessory glands and ductus deferens. Real-time polymerase chain reaction (qPCR) revealed higher levels of m-RNA for both receptors in the testis, ampulla, seminal vesicles, and vas deferens, than in the other organs of the reproductive tract (p < 0.05). Western blot analyses showed protein bands compatible with the MT1 in the testis and cauda epididymis, and for the MT2 in the cauda epididymis and deferent duct. Immunohistochemistry analyses revealed the presence of MT1 receptors in spermatogonias, spermatocytes, and spermatids, and MT2 receptors in the newly-formed spermatozoa in the testis, whereas both receptors were located in the epithelial cells of the ampulla, seminal vesicles, and ductus deferens. Indirect immunofluorescence showed significant differences in the immunolocation of both receptors in spermatozoa during their transit in the epididymis. In conclusion, it was demonstrated that melatonin receptors are present in the ram reproductive tract. These results open the way for new studies on the molecular mechanism of melatonin and the biological significance of its receptors. PMID:28335493

  8. Quantitation of selected terpenoids and mercaptans in the dual-purpose hop varieties Amarillo, Citra, Hallertau Blanc, Mosaic, and Sorachi Ace.

    PubMed

    Cibaka, Marie-Lucie Kankolongo; Gros, Jacques; Nizet, Sabrina; Collin, Sonia

    2015-03-25

    Free terpenoids and both free and bound polyfunctional thiols were investigated in five selected dual-purpose hop cultivars. Surprisingly, the dual-purpose Sorachi Ace variety was found to contain higher amounts of farnesene (2101 mg/kg) than aromatic hops such as Saaz but only traces of 3-methylbutylisobutyrate, a compound that usually distinguishes all bitter varieties. All five cultivars investigated here showed an exceptional citrus-like potential explained by either monoterpenic alcohols or polyfunctional thiols. Among the monoterpenic alcohols, β-citronellol at concentrations above 7 mg/kg distinguished Amarillo, Citra, Hallertau Blanc, Mosaic, and Sorachi Ace from Nelson Sauvin and Tomahawk, two previously investigated dual-purpose hops, while linalool (312 mg/kg) and geraniol (211 mg/kg) remained good discriminating compounds for Nelson Sauvin and Tomahawk, respectively. Regarding polyfunctional thiols, higher amounts of 3-sulfanylhexyl acetate (27 μg/kg) characterized the Citra variety. Free 4-sulfanyl-4-methylpentan-2-one proved discriminant for Sorachi Ace, while the bound form is predominant in Nelson Sauvin. On the other hand, an S-conjugate of 3-sulfanylhexan-1-ol was found in Sorachi Ace at levels not far from those previously reported for Cascade, although the free form was undetected here. Both free and bound grapefruit-like 3-sulfanyl-4-methylpentan-1-ol (never evidenced before the present work) emerged as discriminating compounds for the Hallertau Blanc variety. The apotryptophanase assay also allowed us to evidence for the first time an S-conjugate of 2-sulfanylethan-1-ol.

  9. Decadal region-wide and glacier-wide mass balances derived from multi-temporal ASTER satellite digital elevation models. Validation over the Mont-Blanc area

    NASA Astrophysics Data System (ADS)

    Berthier, Etienne; Cabot, Vincent; Vincent, Christian; Six, Delphine

    2016-06-01

    Since 2000, a vast archive of stereo-images has been built by the Advanced Spaceborne Thermal Emission and Reflection (ASTER) satellite. Several studies already extracted glacier mass balances from multi-temporal ASTER digital elevation models (DEMs) but they lacked accurate independent data for validation. Here, we apply a linear regression to a time series of 3D-coregistered ASTER DEMs to estimate the rate of surface elevation changes (dh/dtASTER) and geodetic mass balances of Mont-Blanc glaciers (155 km²) between 2000 and 2014. Validation using field and spaceborne geodetic measurements reveals large errors at the individual pixel level (> 1 m a-1) and an accuracy of 0.2-0.3 m a-1 for dh/dtASTER averaged over areas larger than 1 km². For all Mont-Blanc glaciers, the ASTER region-wide mass balance (-1.05±0.37 m water equivalent (w.e.) a-1) agrees remarkably with the one measured using Spot5 and Pléiades DEMs (-1.06±0.23 m w.e. a-1) over their common 2003-2012 period. This multi-temporal ASTER DEM strategy leads to smaller errors than the simple differencing of two ASTER DEMs. By extrapolating dh/dtASTER to mid-February 2000, we infer a mean penetration depth of about 9±3 m for the C-band Shuttle Radar Topographic Mission (SRTM) radar signal, with a strong altitudinal dependency (range 0-12 m). This methodology thus reveals the regional pattern of glacier surface elevation changes and improves our knowledge of the penetration of the radar signal into snow and ice.

  10. "Franklin: Science, Politics and France"

    NASA Astrophysics Data System (ADS)

    McClellan, James E., III

    2003-04-01

    This presentation traces Benjamin Franklin's career as a "civic scientist" in Old-Regime France. It outlines the initial - and not always positive - reception of Franklin's work on electricity by the community of French scientists in the 1750s. It sketches Franklin's subsequent elevation into the pantheon of French Enlightenment heros, and it details his work as a "civic scientist" while American envoy to France in the 1770s and 1780s, notably his service on the government-sponsored commissions that repudiated the scientific and medical claims of Franz Anton Mesmer. This presentation concludes by examining a few features of Franklin's career that are not completely congruent with our notion of what a "civic scientist" might be, a contrast that is intended to illuminate both Franklin and the concept of "civic scientist."

  11. [End of life in France].

    PubMed

    Vacheron, André

    2013-01-01

    Two major changes in end-of-life management have occured in recent decades: first, because of the increase in life expectancy and the resulting aging of the population, most deaths now involve old or very old people; second, more than two-thirds of deaths occur in a hospital or an institution. Our fellow citizens are afraid of suffering and death. They wish for a peaceful death, as rapid as possible and, in recent surveys, say they favour euthanasia. Yet euthanasia is illegal in France and in most other Western countries (with the exception of the Benelux nations). Palliative care ensures dignity in death, without anxiety of suffering, and is expanding rapidly in France. Léonetti's law of 22 April 2005 ensures the protection of the weakest, who should never be considered unworthy of life, yet is poorly known to the public and even to physicians. It now needs to be applied in practice.

  12. Human coronavirus NL63, France.

    PubMed

    Vabret, Astrid; Mourez, Thomas; Dina, Julia; van der Hoek, Lia; Gouarin, Stéphanie; Petitjean, Joëlle; Brouard, Jacques; Freymuth, François

    2005-08-01

    The human coronavirus NL63 (HCoV-NL63) was first identified in The Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory specimens for HCoV-NL63. Of the 300 samples, 28 (9.3%) were positive for HCoV-NL63. The highest prevalence was found in February (18%). The main symptoms were fever (61%), rhinitis (39%), bronchiolitis (39%), digestive problems (33%), otitis (28%), pharyngitis (22%), and conjunctivitis (17%). A fragment of the spike protein gene was sequenced to determine the variety of circulating HCoV-NL63. Phylogenetic analysis indicated that strains with different genetic markers cocirculate in France.

  13. 76 FR 28308 - Modification of Class E Airspace; Poplar, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... airspace at Poplar Municipal Airport, Poplar, MT. The airport was moved 1.5 Nautical Miles (NM) to the... Airport, Poplar, MT. The airport was moved 1.5 nautical miles to the northeast, and controlled...

  14. [Epidemiology of burns in France].

    PubMed

    Latarjet, Jacques; Ravat, François

    2012-01-01

    As with most traumas, the epidemiology of the "burn" health-event has long been neglected by public health doctors and rarely considered by burns specialists. There were therefore few verified data and many approximations and preconceived ideas. The gathering of information recently undertaken in France enables the reliability of the data to be improved and the diagnostic and demographic elements relating to hospitalised patients with burns to be established.

  15. Field transplantation of the freshwater bivalve Corbicula fluminea along a polymetallic contamination gradient (River Lot, France): 2. Metallothionein response to metal exposure

    SciTech Connect

    Baudrimont, M.; Andres, S.; Metivaud, J.; Lapaquellerie, Y.; Ribeyre, F.; Maillet, N.; Latouche, C.; Boudou, A.

    1999-11-01

    Specimens of the Asiatic clam Corbicula fluminea were transplanted from a clean lacustrine site to four stations along a polymetallic pollution gradient in the river Lot, France, downstream from an old Zn ore treatment facility (see Part 1). From April to September 1996, the authors studied Cd and Zn bioaccumulation and the metallothionein-like metal-binding protein (MT) concentrations by subsampling the ages at t = 0, 21, 49, 85, 120, and 150 d. Marked differences were observed among the four stations. At the most polluted station Riou-Mort, MT concentrations did not increase despite very rapid metal accumulation; all mollusks died between days 49 and 85, suggesting that the metal detoxification mechanisms were overwhelmed at this station. At the next station downstream, the final levels of bioaccumulated metal after 150 d were as high as those at the Riou-Mort station, but in this case the MT concentrations also increased progressively with positive correlations between MT and metal concentrations; no mortality was observed, but a significant growth inhibition was revealed in comparison to the reference site, with a lack of correlation between MT and reduced growth. Subcellular metal partitioning, as determined by size-exclusion chromatography, revealed that most of the Cd was sequestered by MT. In contrast, most of the Zn was bound to low molecular weight proteins, the MT fraction representing only 12% of cytosolic zn. These data show the marked role of MT toward Cd bioaccumulation and toxic effects on this freshwater bivalve species.

  16. Domain Tuning of Bilingual Lexicons for MT

    DTIC Science & Technology

    2003-02-01

    vocabulary—a set of words or terms from a document that indicate the topic or primary content of the text—is nec- essary for many NLP tasks. In monolingual ...specificity impacts the accuracy of text classification (Saku- rai, 1999). In multilingual processing, appropriate translation choices cannot be made...System A statistical MT system has 3 basic components, a language model, a translation model, and a decoder. The language model is a monolingual

  17. Post Eruption Hazards at Mt. Pinatubo, Philippines

    NASA Technical Reports Server (NTRS)

    Mouginis-Mark, Peter J.

    2004-01-01

    Our project focused on the investigation of the post-eruption hazards at Mt. Pinatubo (Philippines) using remote sensing data, and field observations of the 1991 eruption deposits. Through the use of multiple satellite images, field work, and the 1996/2000 PacRim data sets, we conducted studies of the co- and post-eruption hazards of the volcano due to erosion and re-deposition of the extensive pyroclastic flow deposits. A major part of this project was the assembly and analysis of a database of over 50 high resolution (1 - 50 m/pixel) images that will facilitate this study. We collected Ikonos, SPOT, SIR-C/X-SAR, Landsat, ERS, RADARSAT, and ASTER images of the area around Mt. Pinatubo. An example of the changes that could be seen in these data is shown. Our investigation focused on a retrospective analysis of the erosion, redeposition, and re-vegetation of the 1991 pyroclastic flow deposits of Mt. Pinatubo. The primary geologic goal of our work was the analysis of the spatial distribution and volume change of the sources and sinks of materials associated with mudflow ('lahar') events. This included the measurement of river valley gradients and cross-sections using TOPSAR digital elevation data, as we are participating in the PacRim 2000 deployment to the Philippines specifically so that we can collect a second set of TOPSAR data that can then be used to create a topographic difference image of the volcano. The main results from this multi-sensor study have been published as Torres et al.. A discussion of the methodology that we used to assemble an appropriate database was included in Mouginis-Mark and Domergue-Schmidt. As part of an educational outreach effort, we also helped the Philippine Institute of Volcanology and Seismology (PHIVOLCS) in the Philippines to use NASA data to study Mt. Pinatubo and other Filipino volcanoes.

  18. Mt. Pinatubo Volcano - Post Eruption, Luzon, Philippines

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Mt. Pinatubo on the island of Luzon (14.5N, 120.5E) erupted catastrophically in June 1991 after over 600 years of inactivity. Partially obscured by clouds in this post eruption photo, the crater is not obvious in this scene but the blowout area, in the once heavily forested region, is easily observed as lava flow, ash fallout, mud slide and debris trails mar the landscape. Clark AFB, once the crossroads of the SW Pacific can only partially be seen.

  19. Graphs for Isotopes of 109-Mt (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides a graphic representation of nucleon separation energies and residual interaction parameters for isotopes of the chemical element 109-Mt (Meitnerium, atomic number Z = 109).

  20. MtDNA COI-COII marker and drone congregation area: an efficient method to establish and monitor honeybee (Apis mellifera L.) conservation centres.

    PubMed

    Bertrand, Bénédicte; Alburaki, Mohamed; Legout, Hélène; Moulin, Sibyle; Mougel, Florence; Garnery, Lionel

    2015-05-01

    Honeybee subspecies have been affected by human activities in Europe over the past few decades. One such example is the importation of nonlocal subspecies of bees which has had an adverse impact on the geographical repartition and subsequently on the genetic diversity of the black honeybee Apis mellifera mellifera. To restore the original diversity of this local honeybee subspecies, different conservation centres were set up in Europe. In this study, we established a black honeybee conservation centre Conservatoire de l'Abeille Noire d'Ile de France (CANIF) in the region of Ile-de-France, France. CANIF's honeybee colonies were intensively studied over a 3-year period. This study included a drone congregation area (DCA) located in the conservation centre. MtDNA COI-COII marker was used to evaluate the genetic diversity of CANIF's honeybee populations and the drones found and collected from the DCA. The same marker (mtDNA) was used to estimate the interactions and the haplotype frequency between CANIF's honeybee populations and 10 surrounding honeybee apiaries located outside of the CANIF. Our results indicate that the colonies of the conservation centre and the drones of the DCA show similar stable profiles compared to the surrounding populations with lower level of introgression. The mtDNA marker used on both DCA and colonies of the conservation centre seems to be an efficient approach to monitor and maintain the genetic diversity of the protected honeybee populations.

  1. Modeling the Geologic History of Mt. Sharp

    NASA Technical Reports Server (NTRS)

    Pascuzzo, A.; Allen, C.

    2015-01-01

    Gale is an approximately 155 km diameter crater located on the martian dichotomy boundary (5 deg S 138 deg E). Gale is estimated to have formed 3.8 - 3.5 Gya, in the late Noachian or early Hesperian. Mt. Sharp, at the center of Gale Crater, is a crescent shaped sedimentary mound that rises 5.2 km above the crater floor. Gale is one of the few craters that has a peak reaching higher than the rim of the crater wall. The Curiosity rover is currently fighting to find its way across a dune field at the northwest base of the mound searching for evidence of habitability. This study used orbital images and topographic data to refine models for the geologic history of Mt. Sharp by analyzing its morphological features. In addition, it assessed the possibility of a peak ring in Gale. The presence of a peak ring can offer important information to how Mt. Sharp was formed and eroded early in Gale's history.

  2. Mt. Kilimanjaro expedition in earth science education

    NASA Astrophysics Data System (ADS)

    Sparrow, Elena; Yoshikawa, Kenji; Narita, Kenji; Brettenny, Mark; Yule, Sheila; O'Toole, Michael; Brettenny, Rogeline

    2010-05-01

    Mt. Kilimanjaro, Africa's highest mountain is 5,895 meters above sea level and is located 330 km south of the equator in Tanzania. In 1976 glaciers covered most of Mt. Kilimanjaro's summit; however in 2000, an estimated eighty percent of the ice cap has disappeared since the last thorough survey done in 1912. There is increased scientific interest in Mt. Kilimanjaro with the increase in global and African average temperatures. A team of college and pre-college school students from Tanzania, South Africa and Kenya, teachers from South Africa and the United States, and scientists from the University of Alaska Fairbanks in the United States and Akita University in Japan, climbed to the summit of Mt Kilimanjaro in October 2009. They were accompanied by guides, porters, two expedition guests, and a videographer. This expedition was part of the GLOBE Seasons and Biomes Earth System Science Project and the GLOBE Africa science education initiative, exploring and contributing to climate change studies. Students learned about earth science experientially by observing their physical and biological surroundings, making soil and air temperature measurements, participating in discussions, journaling their experience, and posing research questions. The international trekkers noted the change in the biomes as the altitude, temperature and conditions changed, from cultivated lands, to rain forest, heath zone, moorland, alpine desert, and summit. They also discovered permafrost, but not at the summit as expected. Rather, it was where the mountain was not covered by a glacier and thus more exposed to low extreme temperatures. This was the first report of permafrost on Mt. Kilimanjaro. Classrooms from all over the world participated in the expedition virtually. They followed the trek through the expedition website (http://www.xpeditiononline.com/) where pictures and journals were posted, and posed their own questions which were answered by the expedition and base camp team members

  3. METHYLATION OF ARSENIC BY RECOMBINANT HUMAN AS3MT/287M AND AS3MT/287T POLYMORPHS

    EPA Science Inventory

    Arsenic (+3 oxidation state) methyltransferase (AS3MT) is the key enzyme in the pathway for methylation of inorganic arsenic (iAs). AS3MT polymorphism is, in part, responsible for interindividual differences in iAs metabolism. AS3MT/M287T polymorphism that is found in ~ 10% of C...

  4. Genetic Diversity of Talpa Europaea and Nova Hanta Virus (NVAV) in France

    PubMed Central

    Hugot, Jean-Pierre; Gu, Se Hun; Feliu, Carlos; Ventur, Jacint; Ribas, Alexis; Dormion, Jerôme; Yanagihara, Richard; Nicolas, Violaine

    2014-01-01

    Summary Nova hantavirus (NVAV) was first identified in a single European mole (Talpa europaea), captured in Hungary. Analysis of lung tissues from 94 moles captured in France revealed NVAV in 50%. Based on the genetic diversity of the cytochrome b mtDNA, moles collected in Poitiers and Bordeaux were more closely related to the Iberian mole (T. occidentalis), a species previously assumed to be restricted to the Iberian Peninsula. Several hypotheses are discussed to explain these observations: 1) presence of hitherto unnoticed T. occidentalis in southwestern France; 2) existence of an ancient mitochondrial introgression phenomenon between the two Talpa species, producing a particular phenotype in some hybrids; 3) existence of a hybrid zone between the two species; and 4) existence of a new Talpa species. NVAV was not detected in the southwestern moles, which begs the question of the potential presence of a particular Hantavirus sp. in this population and/or in the Iberian moles. PMID:25530620

  5. Learning motion discrimination with suppressed and un-suppressed MT.

    PubMed

    Thompson, Benjamin; Liu, Zili

    2006-06-01

    Perceptual learning of motion direction discrimination is generally thought to rely on the middle temporal area of the brain (MT/V5). A recent study investigating learning of motion discrimination when MT was psychophysically suppressed found that learning was possible with suppressed MT, but only when the task was sufficiently easy [Lu, H., Qian, N., Liu, Z. (2004). Learning motion discrimination with suppressed MT. Vision Research 44, 1817-1825]. We investigated whether this effect was indeed due to MT suppression or whether it could be explained by task difficulty alone. By comparing learning of motion discrimination when MT was suppressed vs. un-suppressed, at different task difficulties, we found that task difficulty alone could not explain the effects. At the highest difficulty, learning was not possible with suppressed MT, confirming [Lu, H., Qian, N., Liu, Z. (2004). Learning motion discrimination with suppressed MT. Vision Research 44, 1817-1825]. In comparison, learning was possible with un-suppressed MT at the same difficulty level. At the intermediate task difficulty, there was a clear learning disadvantage when MT was suppressed. Only for the easiest level of difficulty, did learning become equally possible for both suppressed and un-suppressed conditions. These findings suggest that MT plays an important role in learning to discriminate relatively fine differences in motion direction.

  6. France: Nukes Stuck between NATO and EU

    DTIC Science & Technology

    2013-03-01

    an enhancement of France’s profile within European defense and deterrence would fulfill the fondest Gaullist aspirations for France as a world power...Thus, ultimately, this thesis argues that although France may aspire to take center stage in European nuclear defense, it is in no practical or...the Gaullist aspirations for France as a world power and for European defense autonomy. On the other hand, practical limits—economic, political, and

  7. [Access to medicines in France].

    PubMed

    Bouvenot, Gilles; Bouvenot, Julien

    2009-03-01

    In France the total cost of medicinal products reimbursed by health insurers in 2007 was over 25 thousand million euros, and access to new drugs is neither restricted nor rationed, despite the unfavorable economic situation. In 2007 and 2008 the Transparency Commission (TC) of the French National Authority for Health (Haute Autorité de Santé) approved the reimbursement of 97% of new drugs and new indications for existing products, within 90 days on average. The 3% of medicinal products that were not approved did not represent therapeutic advances and could be considered to be of dubious utility. If evaluation of new drugs is to be an independent process, then HAS must not only be independent of the decision-maker, funding bodies and commercial firms, but must also be a purely medical and technical organization. This implies removing all financial consideration from the picture, including the size of the target population that may qualify for a new treatment. This system could be further improved by creating special procedures to promote funding for innovations outside the marketing authorization system, thereby providing patients with faster access to the drugs they need; these procedures would include temporary authorisation, temporary treatment protocols, and a special-case function for treatment of chronic and rare conditions. Currently, new treatments produced by the pharmaceutical industry are paid for by national funding bodies and, from this point of view, it is difficult to argue that drug innovation is under-supported in France. On the other hand, it is well known that France has long been the largest consumer of medicinal drugs, both in Europe and worldwide. Two behavioral patterns partially explain this situation: one is a tendency to believe that drugs are the answer to all health concerns, and the other is a preference for new, more expensive drugs, even though "never" is not necessarily "better".

  8. CFB boiler at Gardanne (France)

    SciTech Connect

    Jaud, P.; Jacquet, L.; Delot, P.; Bayle, F.

    1995-06-01

    Among the new Clean Coal Technologies, {open_quotes}Circulating Fluidized Bed{close_quotes} is one of the most promising. Today, the largest project in commissioning`s the 250 MWe Provence CFB boiler, located near MARSEILLE in the south of France. At such a size, the CFB technique has now reached a capacity corresponding to thermal power plants operated by utilities. This new unit is a very important step towards larger size i.e. 400 MWe and greater. The SO{sub 2} emissions of this CFB boiler are guaranteed to be less than 400 mg / Nm{sup 3} at 6% O{sub 2} with the ratio of Ca/S lower than 3 while total sulfur in local coal used can reach 3.68 %. The purpose of the Provence project was to replace the existing pulverized coal boiler unit 4, commissioned in 1967, of the Provence power plant, with a new CFB boiler while reusing most of the existing equipment. The new boiler has been ordered from GEC ALSTHOM STEIN INDUSTREE (GASI) by Electricite de France (EDF) on behalf of the SOPROLIF consortium. Architect Engineering and construction management was performed by EDF jointly with Charbonnages de France (CdF: the French Coal Board). The 250 MWe CFB boiler is of the superheat-reheat type. The first firing of the boiler is due in April 1995. The poster session will describe the progress in the construction of the plant and provides technical details of the new boiler and auxiliaries.

  9. [Health and politics in France].

    PubMed

    Tabuteau, Didier

    2012-06-01

    Health is a dual notion. It is individual, singular and intimate. It is also collective, statistical and political. The modern problematic of health relies upon a balance of complex relations between individual and collective acceptances of the notion. You can try to outline the evolutions and the main concepts through a quadruple approach: health and politics, health and its professionals, health and society and in the end, health and the State. The relationships between health and politics in France are affected by the historical delay of France in public health, namely because of a structural weakness of the administrative organization of public health. Nevertheless France developed a dense and well organized care system and a universal social protection against the disease. The creation of the health professions in France was marked by a historical opposition between the doctors and the state which led to a failure of hygienist medicine and a fundamental misunderstanding on health insurance. Medical domination led to the organization of a system based on professional dichotomy and the delegation of the regulation skills to the health care professionals. The role of health issues in the French society was deeply renewed by the development of the medical and epidemiological knowledge. This resulted in a new political responsibility in the management of health risks but also in the confirmation of the patients' rights and the role of their associations in the health systems operations and the piloting of public policies. In this environment, the state has recently and progressively confirmed its dominating role in the health sector. A public hospital service was created In the 60's and 70's, then in the 80's there were recurrent interventions in order to control health spendings and eventually in the 90's health safety devices were set up. More recently, a process of health policies institutionalization confirmed this evolution. In the future, health issues should

  10. The MU-RAY project: detector technology and first data from Mt. Vesuvius

    NASA Astrophysics Data System (ADS)

    Ambrosino, F.; Anastasio, A.; Basta, D.; Bonechi, L.; Brianzi, M.; Bross, A.; Callier, S.; Caputo, A.; Ciaranfi, R.; Cimmino, L.; D'Alessandro, R.; D'Auria, L.; de La Taille, C.; Energico, S.; Garufi, F.; Giudicepietro, F.; Lauria, A.; Macedonio, G.; Martini, M.; Masone, V.; Mattone, C.; Montesi, M. C.; Noli, P.; Orazi, M.; Passeggio, G.; Peluso, R.; Pla-Dalmau, A.; Raux, L.; Rubinov, P.; Saracino, G.; Scarlini, E.; Scarpato, G.; Sekhniaidze, G.; Starodubtsev, O.; Strolin, P.; Taketa, A.; Tanaka, H. K. M.; Vanzanella, A.; Viliani, L.

    2014-02-01

    Muon Radiography allows to map the density of a volcanic cone. It is based on the measurement of the attenuation of the flux of muons present in the cosmic radiation on the ground. The MU-RAY project has developed an innovative detector designed for the muon radiography. The main features are the low electric power consumption, robustness and transportability, good spatial resolution and muon time of flight measurement. A 1 m2 detector prototype has been constructed. and collected data at Mt. Vesuvius for approximately 1 month in spring 2013. A second campaign of measurement has been performed at the Puy de Dôme, France, in the last four months of 2013. In this article the principles of muon radiography, the MU-RAY detector and the first results from the collected data will be described.

  11. Eurotra: A European perspective on MT

    SciTech Connect

    Arnold, D.

    1986-07-01

    This paper describes the perspective on Machine Translation taken in the Eurotra project: an R and D project of the European Communities at a relatively early stage. It describes: i) the project's rather challenging aims; ii) the framework of design principles and linguistic and software methodology which are of particular importance given its size, scope, and organization; iii) the proposed representational theories and expressive (programming) languages with which actual instances of MT systems can be constructed. The final section sketches some recent proposals and directions for future research.

  12. Mt. Pinatubo Volcano - Post Eruption, Luzon, Philippines

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Mt. Pinatubo on the island of Luzon (15.5N, 120.0E) erupted catastrophically in June 1991 after over 600 years of inactivity. This is the first shuttle post eruption photo. The north facing crater is not obvious in this scene but the blowout area, in the once heavily forested region, is easily observed as lava flow, ash fallout, mud slide and debris trails mar the landscape. Clark AFB, once the crossroads of the SW Pacific can only partially be seen.

  13. Two year study of CO2, CH4 and N2O dynamics and fluxes in four rivers in Belgium (Meuse, Ourthe, Geer and Blanc Gravier)

    NASA Astrophysics Data System (ADS)

    Borges, Alberto V.; Darchambeau, François; Beulen, Aurore

    2013-04-01

    Two rivers and two streams close to the city of Liège in Belgium (Meuse, Ourthe, Geer and Blanc Gravier) were sampled to describe the dynamics of CO2, CH4 and N2O (for the first time in Belgium for freshwaters). The four systems were chosen to cover a gradient of size (stream to river) and of human influence (mainly forested to mainly agricultural watersheds). The study covers the period from February 2011 to March 2013 with weekly sampling in surface waters. The variables were very contrasted in the four systems, the Geer showing a strong enrichment in nitrogen NH4+ et NO2-) and phosphorous in relation to the other three systems. The O2 concentrations were much lower, and the concentration of CH4, N2O and pCO2 were much higher in the Geer than in other three systems. The concentrations in CH4, N2O and pCO2 were higher in the Ourthe than in the Meuse and than in the Blanc Gravier. Marked seasonal variations were observed in the 4 systems. In general the concentration of CH4, N2O and pCO2 were higher in summer than in winter. This is related on one hand to the increase of temperature in summer that stimulates bacterial activity. Also in summer, the availability of organic matter for bacterial activity is higher after the spring phytoplankton blooms and also from allochthnous inputs from the watersheds. The increase of temperature and bacterial consumption of O2 in the water column leads to a lesser O2 penetration in the sediments that could stimulate benthic anaerobic processes among which methanogenesis and denitrification, leading to an increase of CH4 and N2O in the water column. Also, the production of N2O by denitrification strongly increases at low O2. During low water, the increase of residence time of the water mass and the decrease of current (decrease of degasing) allow an accumulation of CO2, CH4 and N2O in the water column. On the contrary during high water, dilution and increase of current (increase of degasing) lead to a decrease of concentrations

  14. Improving the Terrain-Based Parameter for the Assessment of Snow Redistribution in the Col du Lac Blanc Area and Comparisons with TLS Snow Depth Data

    NASA Astrophysics Data System (ADS)

    Schön, Peter; Prokop, Alexander; Naaim-Bouvet, Florence; Nishimura, Kouichi; Vionnet, Vincent; Guyomarc'h, Gilbert

    2014-05-01

    Wind and the associated snow drift are dominating factors determining the snow distribution and accumulation in alpine areas, resulting in a high spatial variability of snow depth that is difficult to evaluate and quantify. The terrain-based parameter Sx characterizes the degree of shelter or exposure of a grid point provided by the upwind terrain, without the computational complexity of numerical wind field models. The parameter has shown to qualitatively predict snow redistribution with good reproduction of spatial patterns, but has failed to quantitatively describe the snow redistribution, and correlations with measured snow heights were poor. The objective of our research was to a) identify the sources of poor correlations between predicted and measured snow re-distribution and b) improve the parameters ability to qualitatively and quantitatively describe snow redistribution in our research area, the Col du Lac Blanc in the French Alps. The area is at an elevation of 2700 m and particularly suited for our study due to its constant wind direction and the availability of data from a meteorological station. Our work focused on areas with terrain edges of approximately 10 m height, and we worked with 1-2 m resolution digital terrain and snow surface data. We first compared the results of the terrain-based parameter calculations to measured snow-depths, obtained by high-accuracy terrestrial laser scan measurements. The results were similar to previous studies: The parameter was able to reproduce observed patterns in snow distribution, but regression analyses showed poor correlations between terrain-based parameter and measured snow-depths. We demonstrate how the correlations between measured and calculated snow heights improve if the parameter is calculated based on a snow surface model instead of a digital terrain model. We show how changing the parameter's search distance and how raster re-sampling and raster smoothing improve the results. To improve the parameter

  15. Merging a Terrain-Based Parameter and Snow Particle Counter Data for the Assessment of Snow Redistribution in the Col du Lac Blanc Area

    NASA Astrophysics Data System (ADS)

    Schön, Peter; Prokop, Alexander; Naaim-Bouvet, Florence; Vionnet, Vincent; Guyomarc'h, Gilbert; Heiser, Micha; Nishimura, Kouichi

    2015-04-01

    Wind and the associated snow drift are dominating factors determining the snow distribution and accumulation in alpine areas, resulting in a high spatial variability of snow depth that is difficult to evaluate and quantify. The terrain-based parameter Sx characterizes the degree of shelter or exposure of a grid point provided by the upwind terrain, without the computational complexity of numerical wind field models. The parameter has shown to qualitatively predict snow redistribution with good reproduction of spatial patterns. It does not, however, provide a quantitative estimate of changes in snow depths. The objective of our research was to introduce a new parameter to quantify changes in snow depths in our research area, the Col du Lac Blanc in the French Alps. The area is at an elevation of 2700 m and particularly suited for our study due to its consistently bi-modal wind directions. Our work focused on two pronounced, approximately 10 m high terrain breaks, and we worked with 1 m resolution digital snow surface models (DSM). The DSM and measured changes in snow depths were obtained with high-accuracy terrestrial laser scan (TLS) measurements. First we calculated the terrain-based parameter Sx on a digital snow surface model and correlated Sx with measured changes in snow-depths (Δ SH). Results showed that Δ SH can be approximated by Δ SHestimated = α * Sx, where α is a newly introduced parameter. The parameter α has shown to be linked to the amount of snow deposited influenced by blowing snow flux. At the Col du Lac Blanc test side, blowing snow flux is recorded with snow particle counters (SPC). Snow flux is the number of drifting snow particles per time and area. Hence, the SPC provide data about the duration and intensity of drifting snow events, two important factors not accounted for by the terrain parameter Sx. We analyse how the SPC snow flux data can be used to estimate the magnitude of the new variable parameter α . To simulate the development

  16. New Radioligands for Describing the Molecular Pharmacology of MT1 and MT2 Melatonin Receptors

    PubMed Central

    Legros, Céline; Matthey, Ulrich; Grelak, Teresa; Pedragona-Moreau, Sandrine; Hassler, Werner; Yous, Saïd; Thomas, Emmanuel; Suzenet, Franck; Folleas, Benoît; Lefoulon, François; Berthelot, Pascal; Caignard, Daniel-Henri; Guillaumet, Gérald; Delagrange, Philippe; Brayer, Jean-Louis; Nosjean, Olivier; Boutin, Jean A.

    2013-01-01

    Melatonin receptors have been studied for several decades. The low expression of the receptors in tissues led the scientific community to find a substitute for the natural hormone melatonin, the agonist 2-[125I]-iodomelatonin. Using the agonist, several hundreds of studies were conducted, including the discovery of agonists and antagonists for the receptors and minute details about their molecular behavior. Recently, we attempted to expand the panel of radioligands available for studying the melatonin receptors by using the newly discovered compounds SD6, DIV880, and S70254. These compounds were characterized for their affinities to the hMT1 and hMT2 recombinant receptors and their functionality in the classical GTPγS system. SD6 is a full agonist, equilibrated between the receptor isoforms, whereas S70254 and DIV880 are only partial MT2 agonists, with Ki in the low nanomolar range while they have no affinity to MT1 receptors. These new tools will hopefully allow for additions to the current body of information on the native localization of the receptor isoforms in tissues. PMID:23698757

  17. Evolution of anorthoclase phonolite, Mt. Erebus, Antarctica

    SciTech Connect

    Moore, J.A.; Kyle, P.R.

    1985-01-01

    Over the last 1 m.y. Mt. Erebus (3794 m) has erupted mainly anorthoclase phonolite (AP) and lesser trachyte, kaersutite phonolite and intermediate differentiates. An active convecting AP lava lake, identical in composition to the older lavas, existed from 1972 until late 1984. Most of the rocks define a strongly undersaturated continuous sodic differentiation series, composed of basanite, Ne-hawaiite, Ne-mugearite, Ne-benmoreite and AP. The main phenocryst phases and their ranges are: olivine (Fo 81-43), clinopyroxene (Wo 50-44, En 42-24, Fs 11-30), opaque oxides (Usp 52-79) and feldspar. Major, trace and REE analyses exhibit smooth trends on variation diagrams. REE are strongly LREE enriched and increase from La/sub N/=220 in the basanites to 400 in AP. There are no significant Eu anomalies. Published isotopic data show derivation of the basanite parental magmas from a depleted (/sup 87/Sr//sup 86/Sr=0.703) heterogeneous mantle source similar to that for oceanic island basalts. Crustal contamination is insignificant except in the trachytes. Evolution of the Erebus lineage by fractional crystallization of the above phases plus apatite is supported by mass balance models. Differentiation probably occurred in larger, hotter and lower P/sub H20/ magma chambers compared to the basanite to kaersutite phonolite DVDP lineage (Kyle, 1981) of the neighboring Hut Point Peninsula. Mt. Erebus may mark the site of a major mantle upwelling.

  18. Stereo Image of Mt. Usu Volcano

    NASA Technical Reports Server (NTRS)

    2002-01-01

    On April 3, the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra Satellite captured this image of the erupting Mt. Usu volcano in Hokkaido, Japan. This anaglyph stereo image is of Mt Usu volcano. On Friday, March 31, more than 15,000 people were evacuated by helicopter, truck and boat from the foot of Usu, that began erupting from the northwest flank, shooting debris and plumes of smoke streaked with blue lightning thousands of feet in the air. Although no lava gushed from the mountain, rocks and ash continued to fall after the eruption. The region was shaken by thousands of tremors before the eruption. People said they could taste grit from the ash that was spewed as high as 2,700 meters (8,850 ft) into the sky and fell to coat surrounding towns with ash. A 3-D view can be obtained by looking through stereo glasses, with the blue film through your left eye and red film with your right eye at the same time. North is on your right hand side. For more information, see When Rivers of Rock Flow ASTER web page Image courtesy of MITI, ERSDAC, JAROS, and the U.S./Japan ASTER Science Team

  19. Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease

    PubMed Central

    Nicholls, Thomas J.; Zsurka, Gábor; Peeva, Viktoriya; Schöler, Susanne; Szczesny, Roman J.; Cysewski, Dominik; Reyes, Aurelio; Kornblum, Cornelia; Sciacco, Monica; Moggio, Maurizio; Dziembowski, Andrzej; Kunz, Wolfram S.; Minczuk, Michal

    2014-01-01

    MGME1, also known as Ddk1 or C20orf72, is a mitochondrial exonuclease found to be involved in the processing of mitochondrial DNA (mtDNA) during replication. Here, we present detailed insights on the role of MGME1 in mtDNA maintenance. Upon loss of MGME1, elongated 7S DNA species accumulate owing to incomplete processing of 5′ ends. Moreover, an 11-kb linear mtDNA fragment spanning the entire major arc of the mitochondrial genome is generated. In contrast to control cells, where linear mtDNA molecules are detectable only after nuclease S1 treatment, the 11-kb fragment persists in MGME1-deficient cells. In parallel, we observed characteristic mtDNA duplications in the absence of MGME1. The fact that the breakpoints of these mtDNA rearrangements do not correspond to either classical deletions or the ends of the linear 11-kb fragment points to a role of MGME1 in processing mtDNA ends, possibly enabling their repair by homologous recombination. In agreement with its functional involvement in mtDNA maintenance, we show that MGME1 interacts with the mitochondrial replicase PolgA, suggesting that it is a constituent of the mitochondrial replisome, to which it provides an additional exonuclease activity. Thus, our results support the viewpoint that MGME1-mediated mtDNA processing is essential for faithful mitochondrial genome replication and might be required for intramolecular recombination of mtDNA. PMID:24986917

  20. Keeping mtDNA in Shape between Generations

    PubMed Central

    Stewart, James B.; Larsson, Nils-Göran

    2014-01-01

    Since the unexpected discovery that mitochondria contain their own distinct DNA molecules, studies of the mitochondrial DNA (mtDNA) have yielded many surprises. In animals, transmission of the mtDNA genome is explicitly non-Mendelian, with a very high number of genome copies being inherited from the mother after a drastic bottleneck. Recent work has begun to uncover the molecular details of this unusual mode of transmission. Many surprising variations in animal mitochondrial biology are known; however, a series of recent studies have identified a core of evolutionarily conserved mechanisms relating to mtDNA inheritance, e.g., mtDNA bottlenecks during germ cell development, selection against specific mtDNA mutation types during maternal transmission, and targeted destruction of sperm mitochondria. In this review, we outline recent literature on the transmission of mtDNA in animals and highlight the implications for human health and ageing. PMID:25299061

  1. [Surgical glove use in France].

    PubMed

    Caillot, J L

    2005-01-01

    Since the end of the 19th century, surgeons have used gloves to prevent infectious complications to the patient. The AIDS epidemic of the 1980's sparked the use of universal precautions to protect the surgeon from infection and vice-versa. The interface between surgeon and patient is in effect a two-way street. Surgical techniques must be modified and barrier protection optimized to minimize these risks. A single layer glove is a fragile barrier to blood exposure; unrecognized glove perforations may lead to unrecognized and prolonged exposure. Double gloving, though far from being a widespread practice in France, seems to be the best protection from pathogen exposure. Glove powder and latex allergies have their own inherent risks to both surgeon and patient in the form of latex allergies and adhesive peritonitis. New institutional protocols will be necesssary in order to make powder-free non-latex gloves available to French surgeons.

  2. Identification of S-3-(hexanal)-glutathione and its bisulfite adduct in grape juice from Vitis vinifera L. cv. Sauvignon blanc as new potential precursors of 3SH.

    PubMed

    Thibon, Cécile; Böcker, Caroline; Shinkaruk, Svitlana; Moine, Virginie; Darriet, Philippe; Dubourdieu, Denis

    2016-05-15

    Two main precursors (S-3-(hexan-1-ol)-l-cysteine and S-3-(hexan-1-ol)-l-glutathione) of 3-sulfanylhexanol (3SH, formerly named 3-mercaptohexanol) have been identified so far in grape juice but a correlation between precursor concentrations in grape juices and 3SH concentrations in wines is not always observed. This suggests that there may be other compounds associated with the aromatic potential. In this work, S-3-(hexanal)-glutathione (Glut-3SH-Al) and its bisulfite (Glut-3SH-SO3) adduct were identified in Sauvignon blanc grape juice by liquid chromatography coupled to Fourier transform mass spectrometry experiments. A partial purification of the compounds was carried out by Medium Pressure Liquid Chromatography (MPLC) on the reverse phase using 5L of grape juice. The addition of synthetized Glut-3SH-Al and Glut-3SH-SO3 in the synthetic medium induced a significant release of 3SH after fermentation. Moreover, we demonstrate that Glut-3SH-Al and its bisulfite adduct are present in grape juice and could be considered as new direct 3SH precursors with molar conversion yields close to 0.4%.

  3. 77 FR 52219 - Amendment of Class E Airspace; Lewistown, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-29

    ... aircraft using Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach... surface, at Lewistown Municipal Airport, Lewistown, MT, to accommodate IFR aircraft executing RNAV...

  4. WPA Omnibus Award MT Wind Power Outreach

    SciTech Connect

    Brian Spangler, Manager Energy Planning and Renewables

    2012-01-30

    The objective of this grant was to further the development of Montana's vast wind resources for small, medium, and large scale benefits to Montana and the nation. This was accomplished through collaborative work with wind industry representatives, state and local governments, the agricultural community, and interested citizens. Through these efforts MT Dept Environmental Quality (DEQ) was able to identify development barriers, educate and inform citizens, as well as to participate in regional and national dialogue that will spur the development of wind resources. The scope of DEQ's wind outreach effort evolved over the course of this agreement from the development of the Montana Wind Working Group and traditional outreach efforts, to the current focus on working with the state's university system to deliver a workforce trained to enter the wind industry.

  5. The mutation rate of the human mtDNA deletion mtDNA4977.

    PubMed

    Shenkar, R; Navidi, W; Tavaré, S; Dang, M H; Chomyn, A; Attardi, G; Cortopassi, G; Arnheim, N

    1996-10-01

    The human mitochondrial mutation mtDNA4977 is a 4,977-bp deletion that originates between two 13-bp direct repeats. We grew 220 colonies of cells, each from a single human cell. For each colony, we counted the number of cells and amplified the DNA by PCR to test for the presence of a deletion. To estimate the mutation fate, we used a model that describes the relationship between the mutation rate and the probability that a colony of a given size will contain no mutants, taking into account such factors as possible mitochondrial turnover and mistyping due to PCR error. We estimate that the mutation rate for mtDNA4977 in cultured human cells is 5.95 x 10(-8) per mitochondrial genome replication. This method can be applied to specific chromosomal, as well as mitochondrial, mutations.

  6. 78 FR 67024 - Establishment of Class E Airspace; Glasgow, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-08

    ... Federal Aviation Administration 14 CFR Parts 71 Establishment of Class E Airspace; Glasgow, MT AGENCY... a final rule published in the Federal Register of September 30, 2013, that establishes Class E... aid, Glasgow, MT. A favorable comment from the National Business Aviation Association (NBAA)...

  7. SignMT: An Alternative Language Learning Tool

    ERIC Educational Resources Information Center

    Ditcharoen, Nadh; Naruedomkul, Kanlaya; Cercone, Nick

    2010-01-01

    Learning a second language is very difficult, especially, for the disabled; the disability may be a barrier to learn and to utilize information written in text form. We present the SignMT, Thai sign to Thai machine translation system, which is able to translate from Thai sign language into Thai text. In the translation process, SignMT takes into…

  8. 77 FR 32896 - Modification of Class E Airspace; Billings, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-04

    ... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Billings, MT AGENCY... airspace at Billings Logan International Airport, Billings, MT. Controlled airspace is necessary to... procedures at Billings Logan International Airport. This action will also make a minor adjustment to...

  9. An Evaluation Study of Community Services, Mt. San Antonio College.

    ERIC Educational Resources Information Center

    Lohr, Sue

    A study was conducted by the Community Services Department at Mt. San Antonio College (Mt. SAC) to evaluate participant satisfaction and suggestions for future direction for the department's comprehensive program of non-credit courses. A questionnaire was administered in class to 307 participants between April 1, and June 1, 1987, focusing on…

  10. 77 FR 41259 - Modification of Class E Airspace; Plentywood, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ... airspace at Plentywood Sher-Wood Airport, Plentywood, MT. Controlled airspace is necessary to accommodate... procedures at Plentywood Sher-Wood Airport. This improves the safety and management of Instrument Flight... Plentywood Sher-Wood Airport, Plentywood, MT. Controlled airspace is necessary to accommodate IFR...

  11. 75 FR 41075 - Amendment of Class E Airspace; Bozeman, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Bozeman, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will amend Class E airspace at... proposed rulemaking to amend Class E airspace at Bozeman, MT (75 FR 20321). Interested parties were...

  12. Interface Symbiotic Membrane Formation in Root Nodules of Medicago truncatula: the Role of Synaptotagmins MtSyt1, MtSyt2 and MtSyt3

    PubMed Central

    Gavrin, Aleksandr; Kulikova, Olga; Bisseling, Ton; Fedorova, Elena E.

    2017-01-01

    Symbiotic bacteria (rhizobia) are maintained and conditioned to fix atmospheric nitrogen in infected cells of legume root nodules. Rhizobia are confined to the asymmetrical protrusions of plasma membrane (PM): infection threads (IT), cell wall-free unwalled droplets and symbiosomes. These compartments rapidly increase in surface and volume due to the microsymbiont expansion, and remarkably, the membrane resources of the host cells are targeted to interface membrane quite precisely. We hypothesized that the change in the membrane tension around the expanding microsymbionts creates a vector for membrane traffic toward the symbiotic interface. To test this hypothesis, we selected calcium sensors from the group of synaptotagmins: MtSyt1, Medicago truncatula homolog of AtSYT1 from Arabidopsis thaliana known to be involved in membrane repair, and two other homologs expressed in root nodules: MtSyt2 and MtSyt3. Here we show that MtSyt1, MtSyt2, and MtSyt3 are expressed in the expanding cells of the meristem, zone of infection and proximal cell layers of zone of nitrogen fixation (MtSyt1, MtSyt3). All three GFP-tagged proteins delineate the interface membrane of IT and unwalled droplets and create a subcompartments of PM surrounding these structures. The localization of MtSyt1 by EM immunogold labeling has shown the signal on symbiosome membrane and endoplasmic reticulum (ER). To specify the role of synaptotagmins in interface membrane formation, we compared the localization of MtSyt1, MtSyt3 and exocyst subunit EXO70i, involved in the tethering of post-Golgi secretory vesicles and operational in tip growth. The localization of EXO70i in root nodules and arbusculated roots was strictly associated with the tips of IT and the tips of arbuscular fine branches, but the distribution of synaptotagmins on membrane subcompartments was broader and includes lateral parts of IT, the membrane of unwalled droplets as well as the symbiosomes. The double silencing of synaptotagmins

  13. Interface Symbiotic Membrane Formation in Root Nodules of Medicago truncatula: the Role of Synaptotagmins MtSyt1, MtSyt2 and MtSyt3.

    PubMed

    Gavrin, Aleksandr; Kulikova, Olga; Bisseling, Ton; Fedorova, Elena E

    2017-01-01

    Symbiotic bacteria (rhizobia) are maintained and conditioned to fix atmospheric nitrogen in infected cells of legume root nodules. Rhizobia are confined to the asymmetrical protrusions of plasma membrane (PM): infection threads (IT), cell wall-free unwalled droplets and symbiosomes. These compartments rapidly increase in surface and volume due to the microsymbiont expansion, and remarkably, the membrane resources of the host cells are targeted to interface membrane quite precisely. We hypothesized that the change in the membrane tension around the expanding microsymbionts creates a vector for membrane traffic toward the symbiotic interface. To test this hypothesis, we selected calcium sensors from the group of synaptotagmins: MtSyt1, Medicago truncatula homolog of AtSYT1 from Arabidopsis thaliana known to be involved in membrane repair, and two other homologs expressed in root nodules: MtSyt2 and MtSyt3. Here we show that MtSyt1, MtSyt2, and MtSyt3 are expressed in the expanding cells of the meristem, zone of infection and proximal cell layers of zone of nitrogen fixation (MtSyt1, MtSyt3). All three GFP-tagged proteins delineate the interface membrane of IT and unwalled droplets and create a subcompartments of PM surrounding these structures. The localization of MtSyt1 by EM immunogold labeling has shown the signal on symbiosome membrane and endoplasmic reticulum (ER). To specify the role of synaptotagmins in interface membrane formation, we compared the localization of MtSyt1, MtSyt3 and exocyst subunit EXO70i, involved in the tethering of post-Golgi secretory vesicles and operational in tip growth. The localization of EXO70i in root nodules and arbusculated roots was strictly associated with the tips of IT and the tips of arbuscular fine branches, but the distribution of synaptotagmins on membrane subcompartments was broader and includes lateral parts of IT, the membrane of unwalled droplets as well as the symbiosomes. The double silencing of synaptotagmins

  14. [The occupational physician in France].

    PubMed

    Matsuda, Shinya

    2013-10-01

    The French Labor law defines the role and its allocation criteria of the occupational physician (OP) the same as in Japan. In France, occupational medicine is one of the medical specialties. The OP resident must follow the 4 years clinical training before certification. After having finished their residency, they are entitled to work for the occupational health service office of a company or company association (in the case of small and medium sized companies). The most important characteristics of the French system is that they cover all workers regardless of company size. The main role of the OP is prevention of work related diseases and accidents. They are not allowed to do clinical services except for emergency cases. Their main activities are health examinations, health education, patrol and advice for better working condition. Formerly, it was rather difficult to attract the medical students for OP resident course because of its prevention oriented characteristics. A growing concern about the importance of health management at the work site, however, has changed the situation. Now, the number of candidates for OP resident course is increasing. Their task has expanded to cover mental health and other life style related diseases. The 2011 modification of law redefines the role of the OP as a director of an occupational health service office who has a total responsibility of multidisciplinary services. The French and Japanese occupational health systems have many of similarities. A comparative study by researchers of UOEH is expected to yield useful information.

  15. [Smoking in women in France].

    PubMed

    Hill, C

    1999-10-01

    Surveillance of smoking behavior and study of consequences of smoking on the health of the French population, and particularly the female population, is a public health priority. The amount of tobacco consumed can be determined from sales figures and from surveys. Globally, tobacco sales increased through 1985. According to the available surveys, the proportion of regular smokers has varied little as smoking rate has decreased in men and increased in women. The decrease occurred in all age groups for men and increased only in the 25-49 year age group for women. Smoking is the cause of 60,000 deaths per year in France, 57,000 in the male population and 3,000 in the female population. Despite reinforced legislation (The Veil and Evin laws) which is unfortunately poorly applied, tobacco consumption has not decreased greatly. Funding levels for anti-smoking campaigns are totally insignificant compared with the efforts of the tobacco industry to promote their products. However, the beneficial health effect of stopping smoking is truly great since the risk depends much more on the duration of smoking than on the number of daily cigarettes. In addition, the delay between the cause and consequence is long, the consequences of the increase in tobacco smoking among young women over the last 20 years will not become visible until 20 to 40 years from now. One could wonder why so little effort has been put into anti-smoking campaigns despite the readily available data clearly warranting their promotion.

  16. [Cannabis in France, new insights].

    PubMed

    Costentin, Jean

    2014-03-01

    France holds the record for cannabis use in Europe, especially among adolescents. This drug of abuse is thus mainly used during a very sensitive period of brain development, education, vehicle driving and development of life projects. In addition, synthetic derivatives of tetrahydrocannabinol (THC), which are more noxious than cannabis itself are now appearing on the market. Traficking and cultivation for personnal use have intensified; products proposed for sale are richer in THC; and some methods of consumption (e-cigarettes, vaporizers, water pipes) increase the supply of THC to the lungs and thence to the body and brain. It is in this context that attempts are being made to legalize this drug of abuse. Other attempts are made to disguise it as a medication. Meanwhile, the list of its psychic as well as physical damages grows longer, with some very severe cases of major injuries. This evolution takes place in spite of numerous warnings expressed by the French Academy of Medicine. Subsequently, it is prompted to carefully and vigorously denounce these events. This will be the aim of this thematic session.

  17. Cold wake of Hurricane Frances

    NASA Astrophysics Data System (ADS)

    D'Asaro, Eric A.; Sanford, Thomas B.; Niiler, P. Peter; Terrill, Eric J.

    2007-08-01

    An array of instruments air-deployed ahead of Hurricane Frances measured the three-dimensional, time dependent response of the ocean to this strong (60 ms-1) storm. Sea surface temperature cooled by up to 2.2°C with the greatest cooling occurring in a 50-km-wide band centered 60-85 km to the right of the track. The cooling was almost entirely due to vertical mixing, not air-sea heat fluxes. Currents of up to 1.6 ms-1 and thermocline displacements of up to 50 m dispersed as near-inertial internal waves. The heat in excess of 26°C, decreased behind the storm due primarily to horizontal advection of heat away from the storm track, with a small contribution from mixing across the 26°C isotherm. SST cooling under the storm core (0.4°C) produced a 16% decrease in air-sea heat flux implying an approximately 5 ms-1 reduction in peak winds

  18. Spotlight on the relevance of mtDNA in cancer.

    PubMed

    Cruz-Bermúdez, A; Vicente-Blanco, R J; Gonzalez-Vioque, E; Provencio, M; Fernández-Moreno, M Á; Garesse, R

    2017-04-01

    The potential role of the mitochondrial genome has recently attracted interest because of its high mutation frequency in tumors. Different aspects of mtDNA make it relevant for cancer's biology, such as it encodes a limited but essential number of genes for OXPHOS biogenesis, it is particularly susceptible to mutations, and its copy number can vary. Moreover, most ROS in mitochondria are produced by the electron transport chain. These characteristics place the mtDNA in the center of multiple signaling pathways, known as mitochondrial retrograde signaling, which modifies numerous key processes in cancer. Cybrid studies support that mtDNA mutations are relevant and exert their effect through a modification of OXPHOS function and ROS production. However, there is still much controversy regarding the clinical relevance of mtDNA mutations. New studies should focus more on OXPHOS dysfunction associated with a specific mutational signature rather than the presence of mutations in the mtDNA.

  19. Developing equine mtDNA profiling for forensic application.

    PubMed

    Gurney, Susan M R; Schneider, Sandra; Pflugradt, René; Barrett, Elizabeth; Forster, Anna Catharina; Brinkmann, Bernd; Jansen, Thomas; Forster, Peter

    2010-11-01

    Horse mtDNA profiling can be useful in forensic work investigating degraded samples, hair shafts or highly dilute samples. Degraded DNA often does not allow sequencing of fragments longer than 200 nucleotides. In this study we therefore search for the most discriminatory sections within the hypervariable horse mtDNA control region. Among a random sample of 39 horses, 32 different sequences were identified in a stretch of 921 nucleotides. The sequences were assigned to the published mtDNA types A-G, and to a newly labelled minor type H. The random match probability within the analysed samples is 3.61%, and the average pairwise sequence difference is 15 nucleotides. In a "sliding window" analysis of 200-nucleotide sections of the mtDNA control region, we find that the known repetitive central motif divides the mtDNA control region into a highly diverse segment and a markedly less discriminatory segment.

  20. 75 FR 16839 - Sorbitol From France

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Sorbitol From France AGENCY: United States International Trade Commission. ACTION: Revised schedule for the subject review. DATES: Effective Date: Date of Commission approval. FOR...

  1. Demoiselles and Drafts from Italy and France.

    ERIC Educational Resources Information Center

    Picard, M. Dane

    1988-01-01

    Recounts the adventures of a journey taken through France and Italy. Makes an analogy of this trip to that of the one Charles Dickens took in 1844. Describes silicified horizons of the southern Paris Basin, moraines, outcrops, and "Hoodoos." (RT)

  2. Women's Employment in France: Protection or Equality.

    ERIC Educational Resources Information Center

    Devaud, Marcelle; Levy, Martine

    1980-01-01

    Reviews the origin and evolution of special protection laws in France for employed women, describes those measures that still exist, and explains what employers, unions, and the authorities think of them. Discusses pregnancy, family responsibilities, and technological progress. (CT)

  3. mtDNAprofiler: a Web application for the nomenclature and comparison of human mitochondrial DNA sequences.

    PubMed

    Yang, In Seok; Lee, Hwan Young; Yang, Woo Ick; Shin, Kyoung-Jin

    2013-07-01

    Mitochondrial DNA (mtDNA) is a valuable tool in the fields of forensic, population, and medical genetics. However, recording and comparing mtDNA control region or entire genome sequences would be difficult if researchers are not familiar with mtDNA nomenclature conventions. Therefore, mtDNAprofiler, a Web application, was designed for the analysis and comparison of mtDNA sequences in a string format or as a list of mtDNA single-nucleotide polymorphisms (mtSNPs). mtDNAprofiler which comprises four mtDNA sequence-analysis tools (mtDNA nomenclature, mtDNA assembly, mtSNP conversion, and mtSNP concordance-check) supports not only the accurate analysis of mtDNA sequences via an automated nomenclature function, but also consistent management of mtSNP data via direct comparison and validity-check functions. Since mtDNAprofiler consists of four tools that are associated with key steps of mtDNA sequence analysis, mtDNAprofiler will be helpful for researchers working with mtDNA. mtDNAprofiler is freely available at http://mtprofiler.yonsei.ac.kr.

  4. Napoli and Volcanism - Vesuvius and Mt. Etna

    NASA Technical Reports Server (NTRS)

    2002-01-01

    For more than 240 million years the region now known as Italy has been the scene of episodic volcanic activity. East-southeast of Napoli (Naples) stands the imposing cone of Vesuvius, which erupted explosively in 79 A.D. to bury Pompeii and Herculaneum. More recently, when the crew of Space Shuttle mission STS-104 captured this view, Mt. Etna (Sicily, not seen in this image, but photographed the day before) was spewing ash and gas thousands of meters into the air, some of which can be seen as a brownish smear over Isola d' Ischia and the Tyrrhenian Sea. The Appenine ranges extend from northern Italy, down the boot of the peninsula and westward into Sicily. This photograph of the Appenino Napoletano is part of an 18-frame stereophoto mapping strip that spans the entire mountain chain. The almost 1200-km-long belt of volcanoes and folded/faulted mountains is a result of the ongoing collision of Africa and Eurasia, accompanied by the progressive closing of the Mediterranean Sea. Using overlapping pairs of stereophotos, and a special viewer, scientists can get a three-dimensional perspective on the ranges that surpasses any image viewed alone. For more information, see another image of Mt. Vesuvius, taken by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER). References: Behncke, Boris, 2000, Vesuvio - The eruption of A.D. 79: Italy's Volcanoes - The Cradle of Volcanology [http://www.geo.mtu.edu/boris/VESUVIO_79.html (accessed 10/18/01)] Doglioni, C., and Flores, G., 1997, Italy, in Moores, E. M., and Fairbridge, R. W., editors, Encyclopedia of European and Asian Regional Geology: London, Chapman and Hall, p. 414-435 Shuttle photograph STS104-710-60 was taken 23 July 2001 from the orbiter Atlantis using a Hasselblad camera with 250-mm lens. The image is provided by the Earth Sciences and Image Analysis Laboratory at Johnson Space Center. The entire mapping series (of frames numbered in sequence from 50 through 68) can also be downloaded from the

  5. [Smoking and electronic cigarettes in France].

    PubMed

    Berlin, Ivan

    2016-12-01

    France is one of the developed countries where the prevalence of tobacco use is the highest. The reduction of incidence and prevalence of tobacco use in the near future would considerably decrease tobacco associated mortality and morbidity. The electronic cigarette, a consumer product that delivers pharmacologically active substances, is used by several millions of persons in France. The benefit-risk ratio of electronic cigarette use is unknown, as of today.

  6. Mechanisms for the export of archaeal lipids down the water column in the upwelling area off Cape Blanc, North-West Africa

    NASA Astrophysics Data System (ADS)

    Ebersbach, Friederike; Goldenstein, Nadine; Iversen, Morten; Mollenhauer, Gesine; Hinrichs, Kai-Uwe

    2016-04-01

    Transport mechanisms of microbial membrane lipids from surface waters to the seafloor are poorly understood. In particular, pelagic archaeal glycerol dibiphytanyl glycerol tetraethers (GDGTs) from planktonic archaea are frequently used for reconstruction of ancient sea surface temperatures (Schouten et al. 2013). Because planktonic archaea are too small and neutrally buoyant to sink independently, transport vehicles for efficient export of fossil archaeal biomarkers to the sediment are required. The surface ocean is coupled with the deep ocean through biogenic sinking particles, a process known as the biological pump (Volk and Hoffert 1985). Two different pathways for particle formation, mainly taking place in the mesopelagic zone, are distinguished: Direct aggregation of phytoplankton blooms or grazing, resulting in phyto-detrital aggregates or reprocessed faecal material, respectively. Grazing and packaging into sinking particles is a possible export mechanism for GDGTs (Huguet et al. 2006). Moreover, it is assumed that phyto-detrital aggregates also play an important role in transporting GDGTs to the deep (Mollenhauer et al. 2015), but processes behind this pathway remain unclear. However, there are only few studies that link GDGT signals in sinking particles to the composition of the exported particulate matter (e.g. Yamamoto et al., 2012; Mollenhauer et al. 2015). Here we investigate sinking particles and suspended particulate matter (SPM) from spring blooms in 2012 and 2013 in the upwelling region in the Atlantic Ocean off Cape Blanc, Mauritania. We compare for the first time material from free-floating sediment traps (100, 200 and 400 m; purely sinking particles) with sinking particles and SPM from size fractionated in-situ pump (ISP) filters (several depths between 40 and 2350 m). This setup allows to relate the signal from archaeal lipids to (i) the flux of particulate organic carbon and the particle assemblages as revealed by the characterisation of

  7. Tracking Holocene glacial and high-altitude alpine environments fluctuations from minerogenic and organic markers in proglacial lake sediments (Lake Blanc Huez, Western French Alps)

    NASA Astrophysics Data System (ADS)

    Simonneau, Anaëlle; Chapron, Emmanuel; Garçon, Marion; Winiarski, Thierry; Graz, Yann; Chauvel, Catherine; Debret, Maxime; Motelica-Heino, Mickaël; Desmet, Marc; Di Giovanni, Christian

    2014-04-01

    Holocene palaeoenvironmental evolution and glacial fluctuations at high-altitude in the western French Alps are reconstructed based on a multiproxy approach within Lake Blanc Huez (2550 m a.s.l.) drainage basin. The combination of seismic profiling (3.5 kHz), piston coring and radiocarbon dating in proglacial lacustrine sediments together with a detailed organic analysis of autochthonous and allochthonous supply allows documenting the evolution of glacier activity during the Holocene. Over the last 9700 years, the Holocene lake record has a bimodal pattern whose transition is progressive and occurring between 5400 and 4700 cal BP. During the Early Holocene, the organic lacustrine facies reflects reduced glacial activity in the catchment. This major glacial retreat seems to result from solar forcing and high summer insolation. After 5400 cal BP, lacustrine sedimentation is marked by the gradual increase both of minerogenic supply and soil erosion, suggesting a progressive transition to wetter climatic conditions. This climate change is synchronous both from the gradual decrease of summer insolation and the gradual reorganization of oceanic and atmospheric circulations, characterizing the beginning of the Neoglacial period. Both colder temperature and humid climate induced significant glacier advance, since 4700 cal BP. Over this global trend, three periods are particularly associated with higher runoff processes and higher soil erosion interpreted as wetter time intervals resulting from enhanced northern Westerlies regimes across the North Atlantic and Western Europe. They are dated from 8700 to 7000, 4700 to 2500 and 1200 to 200 cal BP. These wetter phases drastically contrast with periods of reduced glacial activities dated from the Early Bronze Age (ca 3870-3770 cal BP), the Iron Age (ca 2220-2150 cal BP), the Roman period (ca AD115-330) and the Medieval Warm Period (ca AD760-1160). In addition, these dryer periods are associated with mining activities at high-altitude.

  8. Surface and thickness variations of Brenva Glacier tongue (Mont Blanc, Italian Alps) in the second half of the 20th century by historical maps and aerial photogrammetry comparisons

    NASA Astrophysics Data System (ADS)

    D Agata, C.; Zanutta, A.; Muzzu Martis, D.; Mancini, F.; Smiraglia, C.

    2003-04-01

    Aim of this contribution is the evaluation of volumetric and surface variations of Brenva Glacier (Mont Blanc, Italian Alps) during the second half of the 20th century, by GIS-based processing of maps and aerial photogrammetry technique. Brenva Glacier is a typical debris covered glacier, located in a valley on the S-E side of the Mont Blanc. The glacier covers a surface of 7 kmq and shows a length of 7,6 km at maximum. The glacier snout reaches 1415 m a.s.l., which is the lowest glacier terminus of the Italian Alps. To evaluate glacier variations different historical maps were used: 1) The 1959 Map, at the scale 1:5.000, by EIRA (Ente Italiano Rilievi Aerofotogrammetrici, Firenze), from terrestrial photogrammetric survey, published in the Bollettino del Comitato Glaciologico Italiano, 2, n. 19, 1971. 2) The 1971 Map, at the scale 1:5.000, from aerial photogrammetry (Alifoto, Torino) published in the Bollettino del Comitato Glaciologico Italiano, 2, n. 20, 1972. 3) The 1988 Map, at the scale 1:10.000, (Region Aosta Valley, Regional Technical Map) from 1983 aerial photogrammetric survey. 4) The 1999 Map, at the scale 1:10.000, (Region Aosta Valley, Regional Technical Map) from 1991 aerial photogrammetry survey. For the same purpose the following aereal photographs were used: 1) The 1975 image, CGR (Italian General Company aerial Surveys) flight RAVDA (Administrative Autonomous Region Aosta Valley), at the scale 1:17.000. 2) The 1991 image, CGR (Italian General Company aerial Surveys) flight RAVDA (Administrative Autonomous Region Aosta Valley), at the scale 1:17.000. Aerial imageries have been acquired over a long period from 1975 to 1991. The black and white images were scanned at suitable resolution if compared with the imagery scale and several models, representing the glacier tongue area, oriented using the inner and outer orientation parameters delivered with the images, were produced. The digital photogrammetric system, after orientation and matching, produces

  9. [Epidemiology of nephrolithiasis in France].

    PubMed

    Daudon, M

    2005-12-01

    Nephrolithiasis is a frequent disease that affects about 10% of people in western countries. The prevalence of calcium oxalate stones has been constantly increasing during the past fifty years in France as well as in other industrialized countries. Stone composition varies depending to gender and age of patients and also underlines the role of other risk factors and associated pathologies such as body mass index and diabetes mellitus. The decrease in struvite frequency in female patients is the result of a significantly improved diagnostic and treatment of urinary tract infections by urea-splitting bacteria. In contrast, the increasing occurrence of weddellite calculi in stone forming women aged more than 50 years could be the consequence of post-menopausal therapy. A high prevalence of uric acid was found in overweight and obese stone formers and in diabetic ones as well. Another important finding was the increased occurrence with time of calcium oxalate stones formed from papillary Randall's plaques, especially in young patients. Nutritional risk factors for stone disease are well known: they include excessive consumption of animal proteins, sodium chloride and rapidly absorbed glucides, and insufficient dietary intake of fruits and potassium-rich vegetables, which provide an alkaline load. As a consequence, an excessive production of hydrogen ions may induce several urinary disorders including low urine pH, high urine calcium and uric acid excretion and low urine citrate excretion. Excess in calorie intake, high chocolate consumption inducing hyperoxaluria and low water intake are other factors, which favour excessive urine concentration of solutes. Restoring the dietary balance is the first advice to prevent stone recurrence. However, the striking increase of some types of calculi, such as calcium oxalate stones developed from Randall's plaque, should alert to peculiar lithogenetic risk factors and suggests that specific advices should be given to prevent stone

  10. Viscosity controlled magma-carbonate interaction: a comparison of Mt. Vesuvius (Italy) and Mt. Merapi (Indonesia).

    NASA Astrophysics Data System (ADS)

    Blythe, L. S.; Misiti, V.; Masotta, M.; Taddeucci, J.; Freda, C.; Troll, V. R.; Deegan, F. M.; Jolis, E. M.

    2012-04-01

    Magma-carbonate interaction is increasingly seen as a viable and extremely important cause of magma contamination, and the generation of a crustally sourced CO2 phase (Goff et al., 2001; Freda et al., 2010). Even though the process is well recognized at certain volcanoes e.g. Popocatépetl, (Mexico); Merapi, (Indonesia); and Colli Albani, (Italy) (Goff et al., 2001; Deegan et al., 2010; Freda et al., 2010), neither the kinetics of carbonate assimilation nor its consequences for controlling the explosivity of eruptions have been constrained. Here we show the results of magma-carbonate interaction experiments conducted at 1200 °C and 0.5 GPa for varying durations (0 s, 60 s, 90 s and 300 s) for the Mt. Merapi (Indonesia) and Mt. Vesuvius (Italy) volcanic systems. We performed experiments using glassy starting materials specific to each volcano (shoshonite for Mt. Vesuvius, basaltic-andesite for Mt. Merapi) with different degrees of hydration (anhydrous vs hydration with ~ 2 wt % water) and using carbonate fragments of local origin; see Deegan et al., (2010) and Jolis et al., (2011). Experimental products include a gas phase (CO2-rich) and two melt phases, one pristine (Ca-normal) and one contaminated (Ca-rich) separated by a 'contamination front' which propagates outwards from the carbonate clast. Vesicles appear to nucleate in the contaminated glass and then migrate into the pristine one. Both contamination front propagation and bubble migration away from the carbonate are slower in anhydrous basaltic-andesite (Merapi anhydrous series) than in hydrated basaltic-andesite and shoshonite (Merapi and Vesuvius hydrated series), suggesting that assimilation speed is strongly controlled by the degree of hydration and the SiO2 content, both of which influence melt viscosity and hence diffusivity. As the carbonate dissolution proceeds in our experiments, initially dissolved and eventually exsolved CO2 builds up in the contaminated Ca-rich melt phase. Once melt volatile

  11. Comparison of Complementary Reactions in the Production of Mt

    SciTech Connect

    Nelson, Sarah; Gregorich, Kenneth; Dragojevic, Irena; Ellison, Paul; Garcia, Mitch Andre; Gates, Jacklyn; Stavsetra, Liv; Ali, Mazhar; Nitsche, Heino

    2009-01-21

    The new reaction 208Pb(59Co,n)266Mt was studied using the Berkeley Gas-filled Separator at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. A cross section of 7.7+5.2-3.3 pb was measured at a compound nucleus excitation energy of 14.9 MeV. The measured decay properties of 266Mt and its daughters correspond well with existing data. We compare this experimental result to transactinide compound nucleus formation model predictions, and the previously studied 209Bi(58Fe,n)266Mt reaction.

  12. Comparison of complementary reactions in the production of Mt

    SciTech Connect

    Nelson, S. L.; Dragojevic, I.; Ellison, P. A.; Garcia, M. A.; Gates, J. M.; Nitsche, H.; Gregorich, K. E.; Dvorak, J.; Stavsetra, L.; Ali, M. N.

    2009-02-15

    The new reaction {sup 208}Pb({sup 59}Co,n){sup 266}Mt was studied using the Berkeley Gas-filled Separator at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. A cross section of 7.7{sub -3.3}{sup +5.2} pb was measured at a compound nucleus excitation energy of 14.9 MeV. The measured decay properties of {sup 266}Mt and its daughters correspond well with existing data. We compare this experimental result to transactinide compound nucleus formation model predictions, and the previously studied {sup 209}Bi({sup 58}Fe,n){sup 266}Mt reaction.

  13. Stoichiometric expression of mtHsp40 and mtHsp70 modulates mitochondrial morphology and cristae structure via Opa1L cleavage.

    PubMed

    Lee, Byoungchun; Ahn, Younghee; Kang, Sung-Myung; Park, Youngjin; Jeon, You-Jin; Rho, Jong M; Kim, Sung-Woo

    2015-06-15

    Deregulation of mitochondrial heat-shock protein 40 (mtHsp40) and dysfunction of mtHsp70 are associated with mitochondrial fragmentation, suggesting that mtHsp40 and mtHsp70 may play roles in modulating mitochondrial morphology. However, the mechanism of mitochondrial fragmentation induced by mtHsp40 deregulation and mtHsp70 dysfunction remains unclear. In addition, the functional link between mitochondrial morphology change upon deregulated mtHsp40/mtHsp70 and mitochondrial function has been unexplored. Our coimmunoprecipitation and protein aggregation analysis showed that both overexpression and depletion of mtHsp40 accumulated aggregated proteins in fragmented mitochondria. Moreover, mtHsp70 loss and expression of a mtHsp70 mutant lacking the client-binding domain caused mitochondrial fragmentation. Together the data suggest that the molecular ratio of mtHsp40 to mtHsp70 is important for their chaperone function and mitochondrial morphology. Whereas mitochondrial translocation of Drp1 was not altered, optic atrophy 1 (Opa1) short isoform accumulated in fragmented mitochondria, suggesting that mitochondrial fragmentation in this study results from aberration of mitochondrial inner membrane fusion. Finally, we found that fragmented mitochondria were defective in cristae development, OXPHOS, and ATP production. Taken together, our data suggest that impaired stoichiometry between mtHsp40 and mtHsp70 promotes Opa1L cleavage, leading to cristae opening, decreased OXPHOS, and triggering of mitochondrial fragmentation after reduction in their chaperone function.

  14. Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs

    PubMed Central

    Gammage, Payam A.; Gaude, Edoardo; Van Haute, Lindsey; Rebelo-Guiomar, Pedro; Jackson, Christopher B.; Rorbach, Joanna; Pekalski, Marcin L.; Robinson, Alan J.; Charpentier, Marine; Concordet, Jean-Paul; Frezza, Christian; Minczuk, Michal

    2016-01-01

    Mitochondrial diseases are frequently associated with mutations in mitochondrial DNA (mtDNA). In most cases, mutant and wild-type mtDNAs coexist, resulting in heteroplasmy. The selective elimination of mutant mtDNA, and consequent enrichment of wild-type mtDNA, can rescue pathological phenotypes in heteroplasmic cells. Use of the mitochondrially targeted zinc finger-nuclease (mtZFN) results in degradation of mutant mtDNA through site-specific DNA cleavage. Here, we describe a substantial enhancement of our previous mtZFN-based approaches to targeting mtDNA, allowing near-complete directional shifts of mtDNA heteroplasmy, either by iterative treatment or through finely controlled expression of mtZFN, which limits off-target catalysis and undesired mtDNA copy number depletion. To demonstrate the utility of this improved approach, we generated an isogenic distribution of heteroplasmic cells with variable mtDNA mutant level from the same parental source without clonal selection. Analysis of these populations demonstrated an altered metabolic signature in cells harbouring decreased levels of mutant m.8993T>G mtDNA, associated with neuropathy, ataxia, and retinitis pigmentosa (NARP). We conclude that mtZFN-based approaches offer means for mtDNA heteroplasmy manipulation in basic research, and may provide a strategy for therapeutic intervention in selected mitochondrial diseases. PMID:27466392

  15. Zinc metallothionein (MT) induction by parenteral iron and endotoxin: A temporal analysis of hepatic MT mRNA changes

    SciTech Connect

    McCormick, C.C. )

    1991-03-15

    The present study was undertaken to compare the temporal characteristics of iron-induced hepatic MT mRNA accumulation to that effected by endotoxin. Young chicks were given (ip) either endotoxin, ferrous gluconate or an equivalent volume of saline. At various times following injections, liver was obtained from 5 chicks per treatment for total RNA extraction. Equal amounts of total hepatic RNA from each chick were pooled and 10 {mu}g separated by denaturing agarose gel electrophoresis. Hepatic MT mRNA and albumin mRNA were analyzed by Northern blot analysis using synthetic oligonucleotides. The results indicated little temporal difference in the accumulation of hepatic MT mRNA as affected by either endotoxin or iron. In both treatments, MT mRNA was minimally affected at 3 hours post-injection. Maximum accumulation was achieved during a 6 h period from 6 to 12 hours post-injection. At 24 hours, MT mRNA was considerably higher in liver of endotoxin-injected chicks when compared to that of iron-injection chicks. Albumin expression appeared not to be substantially affected by either treatment. The results suggest that the induction of hepatic MT by iron injection is not substantially different than that observed following endotoxin administration. It would be speculative to suggest that the processes by which MT is induced under these conditions are also similar.

  16. Porous aerosol in degassing plumes of Mt. Etna and Mt. Stromboli

    NASA Astrophysics Data System (ADS)

    Shcherbakov, Valery; Jourdan, Olivier; Voigt, Christiane; Gayet, Jean-Francois; Chauvigne, Aurélien; Schwarzenboeck, Alfons; Minikin, Andreas; Klingebiel, Marcus; Weigel, Ralf; Borrmann, Stephan; Jurkat, Tina; Kaufmann, Stefan; Schlage, Romy; Gourbeyre, Christophe; Febvre, Guy; Lapyonok, Tatyana; Frey, Wiebke; Molleker, Sergej; Weinzierl, Bernadett

    2016-09-01

    Aerosols of the volcanic degassing plumes from Mt. Etna and Mt. Stromboli were probed with in situ instruments on board the Deutsches Zentrum für Luft- und Raumfahrt research aircraft Falcon during the contrail, volcano, and cirrus experiment CONCERT in September 2011. Aerosol properties were analyzed using angular-scattering intensities and particle size distributions measured simultaneously with the Polar Nephelometer and the Forward Scattering Spectrometer probes (FSSP series 100 and 300), respectively. Aerosols of degassing plumes are characterized by low values of the asymmetry parameter (between 0.6 and 0.75); the effective diameter was within the range of 1.5-2.8 µm and the maximal diameter was lower than 20 µm. A principal component analysis applied to the Polar Nephelometer data indicates that scattering features of volcanic aerosols of different crater origins are clearly distinctive from angular-scattering intensities of cirrus and contrails. Retrievals of aerosol properties revealed that the particles were "optically spherical" and the estimated values of the real part of the refractive index are within the interval from 1.35 to 1.38. The interpretation of these results leads to the conclusion that the degassing plume aerosols were porous with air voids. Our estimates suggest that aerosol particles contained about 18 to 35 % of air voids in terms of the total volume.

  17. Loparite-(Ce) in rocks of the Lovozero layered complex at Mt. Karnasurt and Mt. Kedykvyrpakhk

    NASA Astrophysics Data System (ADS)

    Pakhomovsky, Ya. A.; Ivanyuk, G. Yu.; Yakovenchuk, V. N.

    2014-12-01

    Following from a mineralogical and petrographic study of loparite-bearing units I-4 at Mt. Karnasurt and II-4 at Mt. Kedykvyrpakhk, loparite-(Ce) is found to be concentrated in thin (10-40 cm) malignite-ijolite layers at the boundary between the underlying nepheline syenite and the overlying foidolite. Skeletal loparite-(Ce) metacrysts occur as inclusions in nepheline, sodalite, natrolite, aegirine, eudialyte, and lomonosovite or within the intergranular space between them. In turn, the characteristic segregations of skeletal loparite-(Ce) metacrysts contain inclusions of natrolite, lomonosovite, rhabdophane-(Ce), labuntsovite, and other relatively low-temperature minerals typical of pegmatites and hydrothermally altered rocks. The chemical composition of loparite-(Ce) varies within narrow limits (Lop59-70Per11-18Lue5-11Tsn4-7 due to an increase in Ca, Ln, Al, and Ti contents and a decrease in Na, Mn, Th, Sr, Fe, and Ta contents in the transitional zone between the underlying nepheline syenite, ore-bearing foidolite-malignite, and overlying ijoliteurtite. Variations in composition are also caused by the lateral isomorphic replacement of Na and Nb with Ln and Ti. The data obtained show that loparite mineralization is related to a pneumatolytic-hydrothermal alteration of foidolite and nepheline syenite along the contact between them.

  18. Eudialyte-group minerals in rocks of Lovozero layered complex at Mt. Karnasurt and Mt. Kedykvyrpakhk

    NASA Astrophysics Data System (ADS)

    Ivanyuk, G. Yu.; Pakhomovsky, Ya. A.; Yakovenchuk, V. N.

    2015-12-01

    Eudialyte-bearing interbeds within layers I-4 (Mt. Karnasurt) and II-4 (Mt. Kedykvyrpakhk) in the layered complex of the Lovozero Pluton are localized symmetrically relative to the loparite-bearing ijolite-malignite layer; the content of eudialyte decreases from underlying nepheline syenite to overlying foidolite. Eudialyte-group minerals fill the interstices between nepheline, sodalite, and microcline-perthite crystals in all rock types and are partially replaced with georgechaoite and minerals of the lovozerite group as a result of hydrothermal alteration. Variations in the chemical composition of the eudialyte-group minerals are mainly controlled by block substitution NaFeZrCl ↔ LnMn(Nb,Ti)S producing eudialyte proper, manganoeudialyte (sharply predominant), kentbrooksite, alluaivite, and a phase intermediate between manganoeudialyte and alluaivite. As the total Ln2O3 content increases, the relative amounts of Ce and La oxides increases linearly in the proportion Ce2O3: La2O3 = 2.5: 1. In the phases containing lower than 3 wt % La2O3, Nd becomes the next REE after Ce. It is very likely that (mangano)eudialyte was mostly formed after parakeldyshite and other anhydrous zirconium-silicate under effect of residual fluids enriched in Ca and Mn, which took part in fenitization of basalt, tuff, and tuffite of the Lovozero Formation.

  19. Motion-dependent representation of space in area MT+

    PubMed Central

    Fischer, Jason; Whitney, David

    2013-01-01

    Summary How is visual space represented in cortical area MT+? At a relatively coarse scale, the organization of MT+ is debated: Retinotopic, spatiotopic, or mixed representations have been proposed. However, none of these entirely explains perceptual localization of objects at a fine spatial scale—a scale relevant for tasks like navigating or manipulating objects. For example, perceived positions of objects are strongly modulated by visual motion: stationary flashes appear shifted in the direction of nearby motion. Does spatial coding in MT+ reflect these shifts in perceived position? We performed an fMRI experiment employing this “flash-drag effect”, and found that flashes presented near motion produced patterns of activity similar to physically shifted flashes in the absence of motion. This reveals a motion-dependent change in the neural representation of object position in human MT+, a process that could help compensate for perceptual and motor delays in localizing objects in dynamic scenes. PMID:23664618

  20. 76 FR 27914 - Television Broadcasting Services; Kalispell, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... From the Federal Register Online via the Government Publishing Office FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Kalispell, MT AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: The Commission has before it a Notice of Proposed Rulemaking...

  1. 75 FR 54419 - Environmental Impact Statement: Yellowstone County, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ... Federal Highway Administration Environmental Impact Statement: Yellowstone County, MT AGENCY: Federal... highway project in Yellowstone County, Montana. FOR FURTHER INFORMATION CONTACT: Brian Hasselbach, Right... (I-90) and Old Highway 312 in or near the city of Billings, Yellowstone County, Montana....

  2. RadNet Air Data From Billings, MT

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Billings, MT from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  3. RadNet Air Data From Kalispell, MT

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Kalispell, MT from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  4. [Utilization of methylphenidate(Ritalin) in France].

    PubMed

    Frances, C; Hoizey, G; Millart, H; Trenque, T

    2002-01-01

    Methylphenidate (Ritalin) is the only psychostimulant approved in France and indicated in attention deficit hyperactivity disorder in children over 6 years. It is under restricted prescription and distribution conditions. As such, it requires a hospital initiated prescription from either a neurology, psychiatry or pediatric specialist and it is covered by the "narcotics" schedule. The French Pharmacovigilance database spontaneous adverse drug reactions reporting, since it was approved in 1995, were analyzed. 21 adverse drug reactions were reported. In 16 cases, methylphenidate was suspected. They were generally non-serious, mild side effects and in most cases promptly resolved. These results do not suggest methylphenidate misuse in France or an overuse in between 1300 and 4000 treated children, to date. Until more information is available concerning the long-term effects of methylphenidate, and in order to limit misuse, inappropriate or overuse, the current prescription and dispensing regulation should be maintained in France, and could well be developed in other countries.

  5. MT1-MMP: universal or particular player in angiogenesis?

    PubMed

    Genís, Laura; Gálvez, Beatriz G; Gonzalo, Pilar; Arroyo, Alicia G

    2006-03-01

    Tumorigenesis involves not only tumor cells that become transformed but also the peritumoral stroma which reacts inducing inflammatory and angiogenic responses. Angiogenesis, the formation of new capillaries from preexisting vessels, is an absolute requirement for tumor growth and metastasis, and it can be induced and modulated by a wide variety of soluble factors. During angiogenesis, quiescent endothelial cells are activated and they initiate migration by degrading the basement membranes through the action of specific proteases, in particular of matrix metalloproteinases (MMPs). Among these, the membrane type 1-matrix metalloproteinase (MT1-MMP) has been identified as a key player during the angiogenic response. In this review, we will summarize the role of MT1-MMP in angiogenesis and the regulatory mechanisms of this protease in endothelial cells. Since our recent findings have suggested that MT1-MMP is not universally required for angiogenesis, we hypothesize that the regulation and participation of MT1-MMP in angiogenesis may depend on the nature of the angiogenic stimulus. Experiments aimed at testing this hypothesis have shown that similarly to the chemokine stromal cell-derived factor-1 (SDF-1)/CXCL12, lipopolysaccharide (LPS) seems to induce the formation of capillary tubes by human or mouse endothelial cells (ECs) in an MT1-MMP-independent manner. The implications of these findings in the potential use of MT1-MMP inhibitors in cancer therapy are discussed.

  6. Revealing the hidden complexities of mtDNA inheritance.

    PubMed

    White, Daniel James; Wolff, Jonci Nikolai; Pierson, Melanie; Gemmell, Neil John

    2008-12-01

    Mitochondrial DNA (mtDNA) is a pivotal tool in molecular ecology, evolutionary and population genetics. The power of mtDNA analyses derives from a relatively high mutation rate and the apparent simplicity of mitochondrial inheritance (maternal, without recombination), which has simplified modelling population history compared to the analysis of nuclear DNA. However, in biology things are seldom simple, and advances in DNA sequencing and polymorphism detection technology have documented a growing list of exceptions to the central tenets of mitochondrial inheritance, with paternal leakage, heteroplasmy and recombination now all documented in multiple systems. The presence of paternal leakage, recombination and heteroplasmy can have substantial impact on analyses based on mtDNA, affecting phylogenetic and population genetic analyses, estimates of the coalescent and the myriad of other parameters that are dependent on such estimates. Here, we review our understanding of mtDNA inheritance, discuss how recent findings mean that established ideas may need to be re-evaluated, and we assess the implications of these new-found complications for molecular ecologists who have relied for decades on the assumption of a simpler mode of inheritance. We show how it is possible to account for recombination and heteroplasmy in evolutionary and population analyses, but that accurate estimates of the frequencies of biparental inheritance and recombination are needed. We also suggest how nonclonal inheritance of mtDNA could be exploited, to increase the ways in which mtDNA can be used in analyses.

  7. Two-stage fluid flow and element transfers in shear zones during collision burial-exhumation cycle: Insights from the Mont Blanc Crystalline Massif (Western Alps)

    NASA Astrophysics Data System (ADS)

    Rolland, Y.; Rossi, M.

    2016-11-01

    The Mont-Blanc Massif was intensely deformed during the Alpine orogenesis: in a first stage of prograde underthrusting at c. 30 Ma and in a second stage of uplift and exhumation at 22-11 Ma. Mid-crustal shear zones of 1 mm-50 m size, neighbouring episyenites (quartz-dissolved altered granite) and alpine veins, have localised intense fluid flow, which produced substantial changes in mineralogy and whole-rock geochemistry. Four main metamorphic zones are oriented parallel to the strike of the massif: (i) epidote, (ii) chlorite, (iii) actinolite-muscovite ± biotite and (iv) muscovite ± biotite. In addition, phlogopite-bearing shear zones occur in the chlorite zone, and calcite-bearing shear zones are locally found in the muscovite zone. The initial chemical composition of the granitic protolith is relatively constant at massif scale, which allows investigating compositional changes related to shear zone activity, and subsequent volume change and elements mobility. The variations of whole-rock composition and mineral chemistry in shear zones reflect variations in fluid/rock ratios and fluid's chemistry, which have produced specific mineral reactions. Estimated time-integrated fluid fluxes are of the order of 106 m3/m2. The mineral assemblages that crystallised upon these fluid-P-T conditions are responsible for specific major and trace element enrichments. The XFe (Fe/Fe + Mg) pattern of shear zone phyllosilicates and the δ13C pattern of vein calcite both show a bell-type pattern across the massif with high values on the massif rims and low values in the centre of the massif. These low XFe and δ13C values are explained by down temperature up-flow of a Fe-Mg-CO2-rich and silica-depleted fluid during stage 1, while the massif was underthrusting. These produced phlogopite, chlorite and actinolite precipitation and quartz hydrolysis, resulting in strong volume losses. In contrast, during stage 2 (uplift), substantial volume gains occurred on the massif rims due to the

  8. Calendar-dated glacier variations in the western European Alps during the Neoglacial: the Mer de Glace record, Mont Blanc massif

    NASA Astrophysics Data System (ADS)

    Le Roy, Melaine; Nicolussi, Kurt; Deline, Philip; Astrade, Laurent; Edouard, Jean-Louis; Miramont, Cécile; Arnaud, Fabien

    2015-01-01

    Holocene glacier records from the western European Alps are still sparse, although a number of sites are well suited to constraining pre- and early- Little Ice Age (LIA) glacier advances. The present study provides the first dendrochronologically-based and calendar-dated Neoglacial glacier chronology for the Mont Blanc massif, French Alps. It is based on the analysis of over 240 glacially buried Pinus cembra subfossil logs and wood remains found either embedded-in-till or as detrital material in the Mer de Glace right lateral moraine. Only a few of the samples were found to be 'formally in situ' but we show that some logs were 'virtually in situ' (not rooted but showing little or no evidence of reworking) and could be used to accurately reconstruct past glacier margin behavior in space and time. Uncertainties regarding the other samples may relate to original growth location and/or to outer wood decay. The resulting dates (followed by a '+') were therefore considered maximum-limiting ages for glacier advances. The main burial events - interpreted as glacier advances - occurred between ca 1655+ and 1544+ BC, between ca 1230+ and 1105+ BC, between ca 1013+ and 962+/937+ BC, at ca 802-777 BC, after 608+ BC, between 312 and 337 AD, between ca 485+ AD and 606+ AD, between 1120 and 1178 AD, between ca 1248 and 1278+/1296 AD, and after 1352+ AD. These advances predate the late LIA maxima known from historical sources. The magnitude of the advances gradually increased to culminate in three near-Neoglacial maxima during the 7th, 12th and 13th centuries AD, followed by a first LIA/Neoglacial maximum in the second half of the 14th century AD. The pattern of Neoglacial events described here is coherent with Central and Eastern Alpine glacier chronologies. This indicates marked synchronicity of late Holocene glacier variability and forcing at a regional scale, although occasional differences could be detected between 'Western' and 'Eastern' records. The Mer de Glace record also

  9. Snow control on active layer and permafrost in steep alpine rock walls (Aiguille du Midi, 3842 m a.s.l, Mont Blanc massif)

    NASA Astrophysics Data System (ADS)

    Magnin, Florence; Westermann, Sebastian; Pogliotti, Paolo; Ravanel, Ludovic; Deline, Philip

    2016-04-01

    Permafrost degradation through the thickening of the active layer and the rising temperature at depth is a crucial process of rock wall stability. The ongoing increase in rock falls observed during hot periods in mid-latitude mountain ranges is regarded as a result of permafrost degradation. However, the short-term thermal dynamics of alpine rock walls are misunderstood since they result of complex processes related to the interaction of local climate variables, heterogeneous snow cover and heat transfers. As a consequence steady-state and long-term changes that can be approached with simpler process mainly related to air temperature, solar radiations and heat conduction were the most common dynamics to be studied so far. The effect of snow on the bedrock surface temperature is increasingly investigated and has already been demonstrated to be an essential factor of permafrost distribution. Nevertheless, its effect on the year-to-year changes of the active layer thickness and of the permafrost temperature in steep alpine bedrock has not been investigated yet, partly due to the lack of appropriate data. We explore the role of snow accumulations on the active layer and permafrost thermal regime of steep rock walls of a high-elevated site, the Aiguille du Midi (AdM, 3842 m a.s.l, Mont Blanc massif, Western European Alps) by mean of a multi-methods approach. We first analyse six years of temperature records in three 10-m-deep boreholes. Then we describe the snow accumulation patterns on two rock faces by means of automatically processed camera records. Finally, sensitivity analyses of the active layer thickness and permafrost temperature towards timing and magnitude of snow accumulations are performed using the numerical permafrost model CryoGrid 3. The energy balance module is forced with local meteorological measurements on the AdM S face and validated with surface temperature measurements at the weather station location. The heat conduction scheme is calibrated with

  10. [Foreign-born youth in France].

    PubMed

    Tribalat, M

    1996-12-01

    Data from an INED survey on migration and social integration (Mobilite Geographique et Insertion Sociale) carried out in France in 1992 are used to examine the process of assimilation of young people aged 20-29 in France. The results show that although there are many problems facing the young of foreign origin, and particularly those of North African origin, the situation concerning their integration into French society has improved significantly over the course of a generation despite the economic and social problems affecting the country that have made the process of assimilation more difficult.

  11. Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states.

    PubMed

    Ochoa-Sanchez, Rafael; Comai, Stefano; Spadoni, Gilberto; Bedini, Annalida; Tarzia, Giorgio; Gobbi, Gabriella

    2014-02-21

    Melatonin (MLT) is a neurohormone implicated in several physiological processes such as sleep. Contrasting results have been produced on whether or not it may act as a hypnotic agent, and the neurobiological mechanism through which it controls the vigilance states has not yet been elucidated. In this study we investigated the effect of MLT (40 mg/kg), a non-selective MT1/MT2 receptor agonist (UCM793, 40 mg/kg), and a selective MT2 partial agonist (UCM924, 40 mg/kg) on the 24-h vigilance states. EEG and EMG sleep-wake patterns were registered across the 24-h light-dark cycle in adult Sprague-Dawley male rats. MLT decreased (-37%) the latency to the first episode of non rapid eye movement sleep (NREMS), enhanced the power of NREMS delta band (+33%), but did not alter the duration of any of the three vigilance states. Differently, UCM793 increased the number of episodes (+52%) and decreased the length of the episodes (-38%) of wakefulness but did not alter the 24-h duration of wakefulness, NREMS and REMS. UCM924 instead reduced the latency (-56%) and increased (+31%) the duration of NREMS. Moreover, it raised the number of REMS episodes (+57%) but did not affect REMS duration. Taken together, these findings show that MLT and non-selective MT1/MT2 receptor agonists do not increase the quantity of sleep but differently influence the three vigilance states. In addition, they support the evidence that selective MT2 receptor agonists increase NREMS duration compared to MLT and non-selective MT1/MT2 agonists.

  12. Kinetic evidence for different mechanisms of interaction of black mamba toxins MT alpha and MT beta with muscarinic receptors.

    PubMed

    Jolkkonen, M; Oras, A; Toomela, T; Karlsson, E; Järv, J; Akerman, K E

    2001-01-01

    By studying the influence of two toxins from the black mamba Dendroaspis polylepis on the kinetics of [3H]-N-methylscopolamine binding to muscarinic acetylcholine receptors from rat cerebral cortex, it was revealed that these toxins, MT alpha and MT beta, interact with the receptors via kinetically distinct mechanisms. MT beta bound to receptors in a one-step, readily reversible process with the dissociation constant K(d)=5.3 microM. The binding mechanism of MTalpha was more complex, involving at least two consecutive steps. A fast receptor-toxin complex formation (K(T)=3.8 microM) was followed by a slow process of isomerisation of this complex (k(i)=1.8 x 10(-2) s(-1), half-time 39 s). A similar two-step interaction mechanism has been established for a related toxin, MT2 from the green mamba D. angusticeps (K(T)=1.4 microM, k(i)=8.3 x 10(-4) s(-1), half-time 840 s). The slow isomerisation process delays the effect of MT alpha and MT2, but increases their apparent potency compared to toxins unable to induce the isomerisation process.

  13. 78 FR 49115 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ...-100-AD; Amendment 39-17285; AD 2012-25-04] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... applies to certain Eurocopter France (Eurocopter) Model AS350B3 helicopters. The reference to Title...

  14. The Formation and Erosion History of Mt. Sharp

    NASA Technical Reports Server (NTRS)

    Allen, Carlton C.; Dapremont, Angela M.

    2014-01-01

    The Curiosity rover is exploring 155 km diameter Gale crater and Mt. Sharp, Gale's 5 km high central mound (Fig. 1). This study addresses the formation and erosion history of Mt. Sharp. Gale lies on the topographic dichotomy between the southern highlands and the northern plains - a drop of over 2 km [1,2]. Altitude differences between the north and south rim reflect this regional slope, as do altitude differences between the deep annulus north of Mt. Sharp and the southern crater floor. Orbiter and rover images demonstrate that most exposed areas on Mt. Sharp consist of thin, sub-parallel units interpreted as sedimentary layers [3]. Gale is typical of the 50 large martian craters that have been totally or partially filled with such layers [4,5]. In many craters these sediments have been deeply eroded. Central Peak and Peak Ring: The highest point on Mt. Sharp, near the crater's center, is interpreted as a central peak [6]. The peak has a massive lower portion and a thin, smooth capping deposit (Fig. 2). Gale's size is transitional between martian craters with single central peaks and craters with peak rings approximately half the crater's diameter [2,6]. The boundaries of Mt. Sharp, as well as an arc of hills to the southeast of the mountain, closely match a circle approximately 80 km in diameter (Fig. 3). This morphology suggests that the Gale impact may have formed both a central peak and a partial peak ring, which is covered by the sediments of Mt. Sharp in the north and possibly exposed in the arc of eroded hills in the southeast quadrant (Figs. 3,4).

  15. Murine Typhus, Reunion, France, 2011–2013

    PubMed Central

    Camuset, Guillaume; Socolovschi, Cristina; Moiton, Marie-Pierre; Kuli, Barbara; Foucher, Aurélie; Poubeau, Patrice; Borgherini, Gianandrea; Wartel, Guillaume; Audin, Héla; Raoult, Didier; Filleul, Laurent; Parola, Philippe; Pagès, Fréderic

    2015-01-01

    Murine typhus case was initially identified in Reunion, France, in 2012 in a tourist. Our investigation confirmed 8 autochthonous cases that occurred during January 2011–January 2013 in Reunion. Murine typhus should be considered in local patients and in travelers returning from Reunion who have fevers of unknown origin. PMID:25625653

  16. A Paradox in Physics Education in France

    ERIC Educational Resources Information Center

    Smigiel, Eddie; Sonntag, Michel

    2013-01-01

    This paper deals with the nature and the level of difficulty of teaching and learning physics in the first year of undergraduate engineering schools in France. Our case study is based on a survey regarding a classic and basic question in applied physics, and which was conducted with a group of second-year students in a post-baccalaureate 1…

  17. 75 FR 39277 - Sorbitol From France; Determination

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-08

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Sorbitol From France; Determination On the basis of the record \\1\\ developed in the subject five-year review, the United States International Trade Commission (Commission) determines, pursuant to section 751(c) of the Tariff Act of 1930 (19...

  18. Frances Rauscher: Music and Reasoning. Interview.

    ERIC Educational Resources Information Center

    Snyder, Neal

    1995-01-01

    Reports on an interview with Frances Rauscher, a research psychologist and musician who has studied the effects of music on the brain. Maintains that students who have studied music have enhanced spatial reasoning. Recommends that music education begin at younger ages. (CFR)

  19. The emergence of cognitive science in France.

    PubMed

    Chamak, B

    1999-10-01

    A comparison between the development of cognitive science in France and the USA enables us to analyze some national differences linked to specific connections between the scientific, military, economic and political worlds. The influence of new practices and tools developed during World War II and the Cold War appears to be of crucial importance in understanding the development of this new field, as well as that of cybernetics, computer science, artificial intelligence and molecular biology. This paper can be considered as a study in how the differing contexts in France and the USA shaped the history of the construction of cognitive science in each of these two countries. In spite of various differences, some common aspects may be pointed out: in both cases, computer experts and psychologists using a computational modelling approach were those first engaged in the construction of cognitive science. If in France neuroscience-oriented cognitive science research was stronger than in the USA, it seems that the artificial intelligence orientation is also of growing importance in France.

  20. Haemovigilance and transfusion safety in France.

    PubMed

    Rouger, P; Noizat-Pirenne, F; Le Pennec, P Y

    2000-01-01

    The risks associated to red cell and platelet transfusions are essentially bound to the polymorphism of blood group antigens and to transfusion transmitted agents including virus, bacterias.... In France, the haemovigilance system and several investigations allowed to measure these different kinds of risks. We also developed analysis of failures in order to prevent errors and accidents to increase blood safety.

  1. World Foods. The Flavor of France.

    ERIC Educational Resources Information Center

    Calhoun, Helen; And Others

    This teacher's guide contains materials to be used in a study of France and its cuisine. Unit 1 provides an overview of French geographic, political, economic, social, and cultural characteristics. Unit 2 studies French food habits, nutrition, food preparation, and meal patterns. Each unit contains a list of objectives (e.g., identify the type of…

  2. Competence: Conceptual Approach and Practice in France

    ERIC Educational Resources Information Center

    Le Deist, Francoise

    2009-01-01

    Purpose: The purpose of this article is to analyse the conceptual approaches to competence and practice in competence management in France. Design/methodology/approach: Extensive literature review, discussion with academic experts in the French competence network of AGRH and interviews concerning developments following the 2003 national agreement…

  3. Transcriptional quiescence of paternal mtDNA in cyprinid fish embryos

    PubMed Central

    Wen, Ming; Peng, Liangyue; Hu, Xinjiang; Zhao, Yuling; Liu, Shaojun; Hong, Yunhan

    2016-01-01

    Mitochondrial homoplasmy signifies the existence of identical copies of mitochondrial DNA (mtDNA) and is essential for normal development, as heteroplasmy causes abnormal development and diseases in human. Homoplasmy in many organisms is ensured by maternal mtDNA inheritance through either absence of paternal mtDNA delivery or early elimination of paternal mtDNA. However, whether paternal mtDNA is transcribed has remained unknown. Here we report that paternal mtDNA shows late elimination and transcriptional quiescence in cyprinid fishes. Paternal mtDNA was present in zygotes but absent in larvae and adult organs of goldfish and blunt-snout bream, demonstrating paternal mtDNA delivery and elimination for maternal mtDNA inheritance. Surprisingly, paternal mtDNA remained detectable up to the heartbeat stage, suggesting its late elimination leading to embryonic heteroplasmy up to advanced embryogenesis. Most importantly, we never detected the cytb RNA of paternal mtDNA at all stages when paternal mtDNA was easily detectable, which reveals that paternal mtDNA is transcriptionally quiescent and thus excludes its effect on the development of heteroplasmic embryos. Therefore, paternal mtDNA in cyprinids shows late elimination and transcriptional quiescence. Clearly, transcriptional quiescence of paternal mtDNA represents a new mechanism for maternal mtDNA inheritance and provides implications for treating mitochondrion-associated diseases by mitochondrial transfer or replacement. PMID:27334806

  4. Les instituts universitaires de technologie en France. (The university institutes of technology in France)

    ERIC Educational Resources Information Center

    Pineau, Gaston

    1971-01-01

    In 1966 France passed legislation naming three types of technical training: two year postbaccalaureate, short-cycle for those without a bachelor's degree, adult education, for those already employed. (MF)

  5. Satellite remote sensing of hailstorms in France

    NASA Astrophysics Data System (ADS)

    Melcón, Pablo; Merino, Andrés; Sánchez, José Luis; López, Laura; Hermida, Lucía

    2016-12-01

    Hailstorms are meteorological phenomena of great interest to the scientific community, owing to their socioeconomic impact, which is mainly on agricultural production. With its global coverage and high spatial and temporal resolution, satellite remote sensing can contribute to monitoring of such events through the development of appropriate techniques. This paper presents an extensive validation in the south of France of a hail detection tool (HDT) developed for the Middle Ebro Valley (MEV). The HDT is based on consecutive application of two filters, a convection mask (CM) and hail mask (HM), using spectral channels of the Meteosat Second Generation (MSG) satellite. The south of France is an ideal area for studying hailstorms, because there is a robust database of hail falls recorded by an extensive network of hailpads managed by the Association Nationale d'Etude et de Lutte contre les Fleáux Atmosphériques (ANELFA). The results show noticeably poorer performance of the HDT in France relative to that in the MEV, with probability of detection (POD) 60.4% and false alarm rate (FAR) 26.6%. For this reason, a new tool to suit the characteristics of hailstorms in France has been developed. The France Hail Detection Tool (FHDT) was developed using logistic regression from channels of the Spinning Enhanced Visible and Infrared Imager (SEVIRI) sensor of the MSG. The FHDT was validated, resulting in POD 69.3% and FAR 15.4%, thus improving hail detection in the study area as compared with the previous tool. The new tool was tested in a case study with satisfactory results, supporting its future practical application.

  6. 78 FR 75579 - Low Enriched Uranium From France

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-12

    ... COMMISSION Low Enriched Uranium From France Determination On the basis of the record \\1\\ developed in the... antidumping duty order on low enriched uranium from France would be likely to lead to continuation or...), entitled Low Enriched Uranium from France: Investigation No. 731-TA-909 (Second Review). By order of...

  7. Aging in France: Population Trends, Policy Issues, and Research Institutions

    ERIC Educational Resources Information Center

    Beland, Daniel; Durandal, Jean-Philippe Viriot

    2013-01-01

    Like in other advanced industrial countries, in France, demographic aging has become a widely debated research and policy topic. This article offers a brief overview of major aging-related trends in France. The article describes France's demographics of aging, explores key policy matters, maps the institutional field of French social gerontology…

  8. 77 FR 18965 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... Directives; Eurocopter France Helicopters AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice... Eurocopter France Model SA341G helicopters. This proposed AD is prompted by an analysis and tests performed... Civile (DGAC), which is the aviation authority for France, has issued French AD No. F-2004-070, dated...

  9. MtDNA haplogroups and elite Korean athlete status.

    PubMed

    Kim, K C; Cho, H I; Kim, W

    2012-01-01

    Mitochondrial DNA (mtDNA) variation has recently been suggested to have an association with athletic performance or physical endurance. Since mtDNA is haploid and lacks recombination, specific mutations in the mtDNA genome associated with human exercise tolerance or intolerance arise and remain in particular genetic backgrounds referred to as haplogroups. To assess the possible contribution of mtDNA haplogroup-specific variants to differences in elite athletic performance, we performed a population-based study of 152 Korean elite athletes [77 sprint/power athletes (SPA) and 75 endurance/middle-power athletes (EMA)] and 265 non-athletic controls (CON). The overall haplogroup distribution of EMA differed significantly from CON (p<0.01), but that of SPA did not. The EMA have an excess of haplogroups M* (OR 4.38, 95% CI 1.63-11.79, p=0.003) and N9 (OR 2.32, 95% CI 0.92-5.81, p=0.042), but a dearth of haplogroup B (OR 0.26, 95% CI 0.09-0.75, p=0.003) compared with the CON. Thus, our data imply that specific mtDNA lineages may provide a significant effect on elite Korean endurance status, although functional studies with larger sample sizes are necessary to further substantiate these findings.

  10. The mitochondrial Italian Human Proteome Project initiative (mt-HPP).

    PubMed

    Urbani, Andrea; De Canio, Michele; Palmieri, Ferdinando; Sechi, Salvatore; Bini, Luca; Castagnola, Massimo; Fasano, Mauro; Modesti, Alessandra; Roncada, Paola; Timperio, Anna Maria; Bonizzi, Luigi; Brunori, Maurizio; Cutruzzolà, Francesca; De Pinto, Vito; Di Ilio, Carmine; Federici, Giorgio; Folli, Franco; Foti, Salvatore; Gelfi, Cecilia; Lauro, Davide; Lucacchini, Antonio; Magni, Fulvio; Messana, Irene; Pandolfi, Pier Paolo; Papa, Sergio; Pucci, Piero; Sacchetta, Paolo

    2013-08-01

    Mitochondria carry maternally inherited genetic material, called the mitochondrial genome (mtDNA), which can be defined as the 25th human chromosome. The chromosome-centric Human Proteome Project (c-HPP) has initially focused its activities addressing the characterization and quantification of the nuclear encoded proteins. Following the last International HUPO Congress in Boston (September 2012) it was clear that however small the mitochondrial chromosome is, it plays an important role in many biological and physiopathological functions. Mutations in the mtDNA have been shown to be associated with dozens of unexplained disorders and the information contained in the mtDNA should be of major relevance to the understanding of many human diseases. Within this paper we describe the Italian initiative of the Human Proteome Project dedicated to mitochondria as part of both programs: chromosome-centric (c-HPP) and Biology/Disease (B/D-HPP). The mt-HPP has finally shifted the attention of the HUPO community outside the nuclear chromosomes with the general purpose to highlight the mitochondrial processes influencing the human health. Following this vision and considering the large interest and evidence collected on the non-Mendelian heredity of Homo sapiens associated with mt-chromosome and with the microbial commensal ecosystem constituting our organism we may speculate that this program will represent an initial step toward other HPP initiatives focusing on human phenotypic heredity.

  11. Spatial precision of population activity in primate area MT

    PubMed Central

    Morley, John W.; Solomon, Samuel G.

    2015-01-01

    The middle temporal (MT) area is a cortical area integral to the “where” pathway of primate visual processing, signaling the movement and position of objects in the visual world. The receptive field of a single MT neuron is sensitive to the direction of object motion but is too large to signal precise spatial position. Here, we asked if the activity of MT neurons could be combined to support the high spatial precision required in the where pathway. With the use of multielectrode arrays, we recorded simultaneously neural activity at 24–65 sites in area MT of anesthetized marmoset monkeys. We found that although individual receptive fields span more than 5° of the visual field, the combined population response can support fine spatial discriminations (<0.2°). This is because receptive fields at neighboring sites overlapped substantially, and changes in spatial position are therefore projected onto neural activity in a large ensemble of neurons. This fine spatial discrimination is supported primarily by neurons with receptive fields flanking the target locations. Population performance is degraded (by 13–22%) when correlations in neural activity are ignored, further reflecting the contribution of population neural interactions. Our results show that population signals can provide high spatial precision despite large receptive fields, allowing area MT to represent both the motion and the position of objects in the visual world. PMID:26041825

  12. Melatonin receptors MT1 and MT2 are expressed in spermatozoa from several seasonal and nonseasonal breeder species.

    PubMed

    González-Arto, Marta; Vicente-Carrillo, Alejandro; Martínez-Pastor, Felipe; Fernández-Alegre, Estela; Roca, Jordi; Miró, Jordi; Rigau, Teresa; Rodríguez-Gil, Joan E; Pérez-Pé, Rosaura; Muiño-Blanco, Teresa; Cebrián-Pérez, José A; Casao, Adriana

    2016-11-01

    Melatonin is a ubiquitous and multipurpose molecule, and one of its roles is to regulate reproduction in some seasonal mammals. Our group has previously reported the variation in the melatonin levels in ram seminal plasma along the year and identified MT1 and MT2 receptors in ram spermatozoa. The objective of this study was to elucidate whether the presence of melatonin receptors (MT1 and MT2) in the sperm plasma membrane, and melatonin in the seminal plasma is related to seasonal breeding. For this purpose, the presence of melatonin receptors and the levels of melatonin in seminal plasma have been examined in several species: donkey and stallion as long-day breeders; red deer as a wild, short-day, highly seasonal breeder (epididymal spermatozoa); bull as a conventional nonseasonal breeder; boar as a seasonal breeder under management techniques; and dog as possible a seasonal breeder not regulated by melatonin. We have detected measurable levels of melatonin in the seminal plasma of all ejaculated semen samples (from donkey, stallion, boar, bull, and dog). Also, and for the first time, we have demonstrated the presence of MT1 and MT2 melatonin receptors in the spermatozoa of all these species, regardless their type of reproduction or sperm source (ejaculated or epididymal), using indirect immunofluorescence techniques and Western blotting. Our findings suggest that melatonin and melatonin receptors may be universally distributed in the reproductive system of mammals and that the sperm melatonin receptors cells may not be necessarily related with seasonal reproduction. Furthermore, the presence of MT1 at the cytoplasmic droplet in immature ejaculated stallion spermatozoa found in one sample and epididymal red deer spermatozoa suggests that melatonin may be involved in specific functions during spermatogenesis and sperm maturation, like protecting spermatozoa from oxidative damage, this activity being mediated through these receptors.

  13. Caenorhabditis elegans metallothionein isoform specificity--metal binding abilities and the role of histidine in CeMT1 and CeMT2.

    PubMed

    Bofill, Roger; Orihuela, Rubén; Romagosa, Míriam; Domènech, Jordi; Atrian, Sílvia; Capdevila, Mercè

    2009-12-01

    Two metallothionein (MT) isoforms have been identified in the model nematode Caenorhabditis elegans: CeMT1 and CeMT2, comprising two polypeptides that are 75 and 63 residues in length, respectively. Both isoforms encompass a conserved cysteine pattern (19 in CeMT1 and 18 in CeMT2) and, most significantly, as a result of their coordinative potential, CeMT1 includes four histidines, whereas CeMT2 has only one. In the present study, we present a comprehensive and comparative analysis of the metal [Zn(II), Cd(II) and Cu(I)] binding abilities of CeMT1 and CeMT2, performed through spectroscopic and spectrometric characterization of the recombinant metal-MT complexes synthesized for wild-type isoforms (CeMT1 and CeMT2), their separate N- and C-terminal moieties (NtCeMT1, CtCeMT1, NtCeMT2 and CtCeMT2) and a DeltaHisCeMT2 mutant. The corresponding in vitro Zn/Cd- and Zn/Cu-replacement and acidification/renaturalization processes have also been studied, as well as protein modification strategies that make it possible to identify and quantify the contribution of the histidine residues to metal coordination. Overall, the data obtained in the present study are consistent with a scenario where both isoforms exhibit a clear preference for divalent metal ion binding, rather than for Cu coordination, although this preference is more pronounced towards cadmium for CeMT2, whereas it is markedly clearer towards Zn for CeMT1. The presence of histidines in these MTs is revealed to be decisive for their coordination performance. In CeMT1, they contribute to the binding of a seventh Zn(II) ion in relation to the M(II)(6)-CeMT2 complexes, both when synthesized in the presence of supplemented Zn(II) or Cd(II). In CeMT2, the unique C-terminal histidine abolishes the Cu-thionein character that this isoform would otherwise exhibit.

  14. Rheology of Crystallizing Basalts from Mt. Nyiragongo and Mt. Nyamuragira D.R.C.

    NASA Astrophysics Data System (ADS)

    Morrison, A. A.; Whittington, A. G.; Sehlke, A.

    2015-12-01

    Mt. Nyiragongo, located within the Virunga Volcanic Province on the western branch of the East African Rift, is known for its persistent lava lake activity as well as devastating eruptions in 1977 and 2002. The 2002 eruption caused a humanitarian crisis when channelized lava flows entered the nearby city of Goma killing 170 people and displacing ~350,000 others. These lavas have extremely low silica contents (39-42 wt.% SiO2) and are very fluid, allowing flows to move rapidly away from the source. We have measured the rheology of lavas from Nyiragongo using a concentric cylinder viscometer at temperatures of ~1220, 1205, 1190, 1175, 1165, and 1145°C. Each experiment starts with a liquid viscosity measurement at 1500˚C, followed by cooling to the desired experimental temperature. The lava spends 10-12 hours at this temperature, with constant stirring, before measurements begin. After measuring at a range of strain rates, the lava is quenched by immersion of the Pt crucible in a water bath. The viscosity is ~32 Pas at the liquidus temperature of ~1220°C, increasing gradually to ~142 Pas at 1165˚C. These viscosity measurements are much lower than most other basaltic compositions including Hawaiian lavas which have a crystal fraction of ~42% and apparent viscosity of ~2000 Pas at 1169°C. Over this temperature range, crystal fraction varies little (1-5% spinel crystals). Interpolating between measurements of the melt viscosity by concentric cylinder and parallel-plate viscometry suggests that at 1165˚C, the viscosity of the starting melt would be ~63 Pas. Consequently, the change in viscosity is due primarily to cooling rather than either the physical or chemical effects of crystallization. The data were collected at strain rates between ~1 and 46 s-1, and are well reproduced using a power-law model with exponents ~0.94 to 0.96. Below 1165˚C, crystal fraction and magma viscosity both increase rapidly. Further experiments at lower temperatures will quantify this

  15. Genetic analysis of the presumptive blood from Louis XVI, King of France.

    PubMed

    Lalueza-Fox, Carles; Gigli, Elena; Bini, Carla; Calafell, Francesc; Luiselli, Donata; Pelotti, Susi; Pettener, Davide

    2011-11-01

    A text on a pyrographically decorated gourd dated to 1793 explains that it contains a handkerchief dipped with the blood of Louis XVI, king of France, after his execution. Biochemical analyses confirmed that the material contained within the gourd was blood. The mitochondrial DNA (mtDNA) hypervariable region 1 (HVR1) and 2 (HVR2), the Y-chromosome STR profile, some autosomal STR markers and a SNP in HERC2 gene associated to blue eyes, were retrieved, and some results independently replicated in two different laboratories. The uncommon mtDNA sequence retrieved can be attributed to a N1b haplotype, while the novel Y-chromosome haplotype belongs to haplogroup G2a. The HERC2 gene showed that the subject analyzed was a heterozygote, which is compatible with a blue-eyed person, as king Louis XVI was. To confirm the identity of the subject, an analysis of the dried heart of his son, Louis XVII, could be undertaken.

  16. EMT and EndMT: regulated in similar ways?

    PubMed

    Saito, Akira

    2013-06-01

    Epithelial-mesenchymal transition (EMT) is an evolutionary conserved developmental process, which is evoked during tumour invasion and metastasis. In the tumour microenvironment, a variety of resident and recruited cells participate in tumour progression. Kawata et al. demonstrated an experimental model where proinflammatory cytokines derived from macrophages could enhance EMT of cancer cells. Endothelial-mesenchymal transition (EndMT) is originally observed during heart development, and recent studies suggest its role in pathological settings such as cancer and fibrosis. Mihira et al. demonstrated a line of evidence showing endothelial cell plasticity to undergo EndMT in vitro. Both in EMT and EndMT, transforming growth factor-β played pivotal roles, and multiple downstream mechanisms were used, depending on cell context. These recent works unraveled discrete regulatory networks in mesenchymal transition of epithelial and endothelial cells.

  17. Gravity survey of the Mt. Toondina impact structure, South Australia

    NASA Technical Reports Server (NTRS)

    Plescia, J. B.; Shoemaker, E. M.; Shoemaker, C. S.

    1991-01-01

    The Mt. Toondina impact structure is located in northern South Australia, about 45 km south of the town of Oodnadatta. Only the central uplift is exposed. The outcrops at Mt. Toondina reveal a remarkable structural anomaly surrounded by a broad expanse of nearly flat-lying beds of the Bulldog Shale of Early Cretaceous age. A gravity survey was undertaken in 1989 to determine the diameter of the impact structure, define the form of the central uplift, and understand the local crustal structure. Data were collected along two orthogonal lines across the structure. In addition to the profiles, a significant number of measurements were made on and around the central uplift. The 1989 gravity data combined with 1963 gravity data and the seismic reflection data provide an excellent data base to interpret the subsurface structure of the Mt. Toondina feature.

  18. Mitochondrial disease in childhood: mtDNA encoded.

    PubMed

    Saneto, Russell P; Sedensky, Margret M

    2013-04-01

    Since the first description of a mitochondrial DNA (mtDNA)-associated disease in the late 1980s, there have been more than 275 mutations within the mtDNA genome described causing human disease. The phenotypic expression of these disorders is vast, as disturbances of the unique physiology of mitochondria can create a wide range of clinical heterogeneity. Features of heteroplasmy, threshold effect, genetic bottleneck, mtDNA depletion, mitotic segregation, and maternal inheritance have been identified and described as a result of novel biochemical and genetic controls of mitochondrial function. We hope that as we unfold this fascinating part of clinical medicine, the reader will see how alterations in the tapestry of mitochondrial biochemistry and genetics can give rise to human illness.

  19. The eruptive history of the Trous Blancs pit craters, La Réunion Island: The origin of a 24 km long lava flow

    NASA Astrophysics Data System (ADS)

    Walther, Georg; Frese, Ingmar; Di Muro, Andrea; Kueppers, Ulrich; Michon, Laurent; Métrich, Nicole

    2015-04-01

    The assessment of volcanic hazards is strongly based on the past eruptive behaviour of volcanoes and its morphological parameters. Since past eruption characteristics and their frequency provide the best probabilities of such eruptions for the future, understanding the complete eruptive history of a volcano is one of the most powerful tools in assessing the potential hazards or eruptions. At Piton de la Fournaise (PdF) volcano (La Réunion, Indian Ocean), the most frequent style of activity is the effusion of lava flows, which pose the greatest hazard by invasion of inhabited areas and destruction of human property. Here we examined the eruptive history of a previously uninvestigated area, believed to be the origin of a 24 km long lava flow. The eruptions recurrence time of PdF is about one eruption every 9 months in the central caldera. Besides this central activity, eruptive vents have been built along three main rift zones cutting the edifice during the last 50 kyrs. In this study we focused on the largest rift zone of about 15 km width and 20 km length, which extends in a north westerly direction between PdF and the nearby Piton des Neiges volcanic complex. This rift zone is typified by deep seismicity (up to 30 km), emitting mostly primitive magmas, indicative of high fluid pressures (up to 5 kbar) and large volume eruptions. Our area of investigation focused on four consecutively aligned pit craters called the Trous Blancs. These have been identified [1] as the source area of one of the youngest (ca. 6 kyrs) and largest lava field, which extends for 24 km from a height of 1800m asl, passing Le Tampon and Saint Pierre city, until it reaches the coast. To gain insight into the development of this eruption and possible future similar activity, we collected new field data (including stratigraphic logs, a geological map of the area, C-14 dating and geochemical analyses of the eruptive products). Fieldwork revealed that the eruption initiated with intense

  20. Passive monitoring of Mt. Etna and Mt. Yasur to probe the upper atmosphere

    NASA Astrophysics Data System (ADS)

    Assink, J. D.; Le Pichon, A.; Blanc, E.

    2013-12-01

    We present two case studies in which the influence of atmospheric dynamics on infrasound propagation is studied. We make use of a volcanic infrasound data set that has been recorded at infrasound arrays in the vicinity of Mount Etna, Italy (37 N). In addition, we revisit the Mt. Yasur (22 S) dataset. Respectively, over 6 and 10 years of infrasound observables are compared to theoretical estimates obtained from propagation modeling using existing European Centre for Medium-Range Weather Forecasts (ECMWF) atmospheric databases. Long-term detail comparisons such as presented in this study have been unprecedented and are useful for atmospheric modeling and infrasound propagation studies. While a first-order agreement is found, we report on significant discrepancies around the equinox period and during intervals during which anomalous detections occur during the winter, such as during Sudden Stratospheric Warmings (SSWs). We present an inversion study in which we make use of measured trace velocity estimates to predict effective sound speed model updates in a Bayesian framework. Such estimates will be compared to independent wind and temperature measurements that are available through the Atmospheric dynamics Research InfraStructure in Europe (ARISE) network.

  1. Diphtheria: a zoonotic disease in France?

    PubMed

    Bonmarin, Isabelle; Guiso, Nicole; Le Flèche-Matéos, Anne; Patey, Olivier; Patrick, A D Grimont; Levy-Bruhl, Daniel

    2009-06-24

    Thanks to vaccination, diphtheria has almost disappeared in France. The case definition, used for mandatory notification, was expanded in 2003 to include toxin-producing strains of Corynebacterium ulcerans. We describe the epidemiology of diphtheria in France from 1990 to 2008. No cases occurred between 1990 and 2001. Since 2002, 19 cases have been reported: 4 cases due to Corynebacterium diphtheriae related to exposure in endemic countries, and 15 cases due to other corynebacteria, including 4 cases of pseudomembranous pharyngitis, mainly related to contact with domestic animals. High vaccination coverage in the population and sensitive surveillance need to be maintained. Moreover, control measures need to be adapted to the non-C. diphtheriae toxigenic species.

  2. Identifying Water on Mt. Baker and Mt. St. Helens, WA with Geophysics: Implications for Volcanic Landslide Hazards

    NASA Astrophysics Data System (ADS)

    Finn, C.; Bedrosian, P.; Wisniewski, M.; Deszcz-Pan, M.

    2015-12-01

    Groundwater position, abundance, and flow rates within a volcano affect the transmission of fluid pressure, transport of mass and heat and formation of mechanically weak hydrothermal alteration influencing the stability of volcanoes. In addition, eruptions can shatter volcanic rocks, weakening the edifice. Helicopter magnetic and electromagnetic (HEM) data collected over Mt. Baker and Mt. St. Helens volcanoes reveal the distribution of water, shattered volcanic rocks and hydrothermal alteration essential to evaluating volcanic landslide hazards. These data, combined with geological mapping and rock property measurements, indicate the presence of localized <100 m thick zones of water-saturated hydrothermally altered rock beneath Sherman Crater and the Dorr Fumarole Fields at Mt. Baker. Nuclear magnetic resonance data indicate that the hydrothermal clays contain ~50% bound water with no evidence for free water ponded beneath the ice. The HEM data suggest water-saturated fresh volcanic rocks from the surface to the detection limit (~100 m) over the entire summit of Mt. Baker (below the ice). A 50-100 m thick high resistivity layer (>1500 ohm-m) corresponding to domes, debris avalanche, volcanic rocks and glaciers mantles the crater at Mt. St. Helens. Shallow low resistivity layers corresponding to fresh, cold water and hot brines are observed below the high resistivity surface in EM data. Shallow ground water mainly concentrates in shattered dome material in the crater of Mt. St. Helens. Aeromagnetic data indicate the location of basalts sandwiched between debris avalanche deposits and shattered dome material. The combination of the EM and magnetic data help map the location of the shattered dome material that is considered to be the failure surface for the 1980 debris avalanche. The EM data image the regional groundwater table near the base of the volcano. The geophysical identification of groundwater and weak layers constrain landslide hazards assessments.

  3. Melatonin influences somatostatin secretion from human pancreatic δ-cells via MT1 and MT2 receptors.

    PubMed

    Zibolka, Juliane; Mühlbauer, Eckhard; Peschke, Elmar

    2015-03-01

    Melatonin is an effector of the diurnal clock on pancreatic islets. The membrane receptor-transmitted inhibitory influence of melatonin on insulin secretion is well established and contrasts with the reported stimulation of glucagon release from α-cells. Virtually, nothing is known concerning the melatonin-mediated effects on islet δ-cells. Analysis of a human pancreatic δ-cell model, the cell line QGP-1, and the use of a somatostatin-specific radioimmunoassay showed that melatonin primarily has an inhibitory effect on somatostatin secretion in the physiological concentration range. In the pharmacological range, melatonin elicited slightly increased somatostatin release from δ-cells. Cyclic adenosine monophosphate (cAMP) is the major second messenger dose-dependently stimulating somatostatin secretion, in experiments employing the membrane-permeable 8-Br-cAMP. 8-Br-cyclic guanosine monophosphate proved to be of only minor relevance to somatostatin release. As the inhibitory effect of 1 nm melatonin was reversed after incubation of QGP-1 cells with the nonselective melatonin receptor antagonist luzindole, but not with the MT2-selective antagonist 4-P-PDOT (4-phenyl-2-propionamidotetraline), an involvement of the MT1 receptor can be assumed. Somatostatin release from the δ-cells at low glucose concentrations was significantly inhibited during co-incubation with 1 nm melatonin, an effect which was less pronounced at higher glucose levels. Transient expression experiments, overexpressing MT1, MT2, or a deletion variant as a control, indicated that the MT1 and not the MT2 receptor was the major transmitter of the inhibitory melatonin effect. These data point to a significant influence of melatonin on pancreatic δ-cells and on somatostatin release.

  4. Screening programme for congenital toxoplasmosis in France.

    PubMed

    Thulliez, P

    1992-01-01

    The high prevalence of Toxoplasma gondii infection in France led to the establishment of a national screening programme. Preventive measures were progressively introduced, and these became compulsory in 1978 with the result that the incidence of congenital toxoplasmosis is now markedly reduced. Further improvements may include more systematic sampling from women before pregnancy, better and adequate health education and centralized notification of both maternal and congenital cases of toxoplasmosis.

  5. Minimally Invasive Forefoot Surgery in France.

    PubMed

    Meusnier, Tristan; Mukish, Prikesht

    2016-06-01

    Study groups have been formed in France to advance the use of minimally invasive surgery. These techniques are becoming more frequently used and the technique nuances are continuing to evolve. The objective of this article was to advance the awareness of the current trends in minimally invasive surgery for common diseases of the forefoot. The percutaneous surgery at the forefoot is less developed at this time, but also will be discussed.

  6. Enterovirus Migration Patterns between France and Tunisia.

    PubMed

    Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

    2015-01-01

    The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000-2012) and Tunisia (2011-2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs.

  7. Bioelectromagnetics Research in France--An Assessment.

    DTIC Science & Technology

    1984-06-29

    lEanetj’ hr black auf) Over the past decade, France has played a major research role In bicebec- tri~ gnetics (BEN) (studies of the interaction of...materials studied at CNRS; reasonable conclusion. Occupational use animal behavior and electroencephalogram of electromagnetic energy, on the oher...at slightly shorter A crossed -beam apparatus for treatment times and at slightly lower simultaneous spectrophotometric observa- final temperatures

  8. Frances Keesler Graham (1918-2013).

    PubMed

    Berg, W Keith

    2014-09-01

    Frances Keesler Graham, noted psychophysiologist and developmental researcher, died on April 16, 2013. Fran was born in Canastota, New York, on August 1, 1918. Fran's high-quality research, her success in obtaining 39 years of uninterrupted funding, and the very high regard in which she was held among her colleagues led to numerous awards and honors. Fran was demanding but equally willing to provide extensive assistance to students willing to work hard.

  9. Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration

    PubMed Central

    Khiati, Salim; Baechler, Simone A.; Factor, Valentina M.; Zhang, Hongliang; Huang, Shar-yin N.; Dalla Rosa, Ilaria; Sourbier, Carole; Neckers, Leonard; Thorgeirsson, Snorri S.; Pommier, Yves

    2015-01-01

    The liver has an exceptional replicative capacity following partial hepatectomy or chemical injuries. Cellular proliferation requires increased production of energy and essential metabolites, which critically depend on the mitochondria. To determine whether Top1mt, the vertebrate mitochondrial topoisomerase, is involved in this process, we studied liver regeneration after carbon tetrachloride (CCl4) administration. TOP1mt knockout (KO) mice showed a marked reduction in regeneration and hepatocyte proliferation. The hepatic mitochondrial DNA (mtDNA) failed to increase during recovery from CCl4 exposure. Reduced glutathione was also depleted, indicating increased reactive oxygen species (ROS). Steady-state levels of ATP, O2 consumption, mtDNA, and mitochondrial mass were also reduced in primary hepatocytes from CCl4-treated KO mice. To further test whether Top1mt acted by enabling mtDNA regeneration, we tested TOP1mt KO fibroblasts and human colon carcinoma HCT116 cells and measured mtDNA after 3-d treatment with ethidium bromide. Both types of TOP1mt knockout cells showed defective mtDNA regeneration following mtDNA depletion. Our study demonstrates that Top1mt is required for normal mtDNA homeostasis and for linking mtDNA expansion with hepatocyte proliferation. PMID:26305952

  10. A paradox in physics education in France

    NASA Astrophysics Data System (ADS)

    Smigiel, Eddie; Sonntag, Michel

    2013-07-01

    This paper deals with the nature and the level of difficulty of teaching and learning physics in the first year of undergraduate engineering schools in France. Our case study is based on a survey regarding a classic and basic question in applied physics, and which was conducted with a group of second-year students in a post-baccalaureateThe French baccalaureate (baccalauréat) is the examination students must pass to graduate from high school. undergraduate engineering school. The responses to the survey indicate that many students fall into a kind of mathematical ‘formalism’, which prevents them from understanding the actual physics behind the question. This leads us to believe that we must reconsider the way that physics is taught. An analysis of a physics teaching sequence in French and English undergraduate textbooks confirms the weight given to mathematical formalism in France. When approached from a purely mathematical angle, physics becomes a long and slow process of assimilation of the specific scientific culture that underlies the teaching model used in classes préparatoires, classes that are usually presented as a model of academic excellence. However, this model appears to be less suitable when teaching more ‘ordinary students’, who respond better when taken through a ‘detour’ of the ‘important roots’ of physics. This paper shows that in France historically rooted pedagogical traditions persist, ignoring the latest advances in research on science teaching.

  11. 77 FR 44120 - Establishment of Class E Airspace; Roundup, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-27

    ... airspace at Roundup Airport, Roundup, MT, to accommodate aircraft using new Area Navigation (RNAV) Global... action under 1 CFR part 51, subject to the annual revision of FAA Order 7400.9 and publication of... the TAAs. The airspace in question includes the following areas where Class E begins at 14,500...

  12. 78 FR 59807 - Establishment of Class E Airspace; Glasgow, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... airspace at the Glasgow VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation... the surface, at the Glasgow VOR/DME navigation aid, Glasgow, MT, to accommodate IFR aircraft under... within the scope of that authority as it establishes controlled airspace at the Glasgow VOR/DME,...

  13. 76 FR 9991 - Television Broadcasting Services; Kalispell, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ... From the Federal Register Online via the Government Publishing Office ] FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 Television Broadcasting Services; Kalispell, MT AGENCY: Federal Communications... CFR 1.415 and 1.420. List of Subjects in 47 CFR Part 73 Television, Television broadcasting. For...

  14. Mt. San Antonio College Matriculation Study: Fall 1986-Spring 1989.

    ERIC Educational Resources Information Center

    Hall, Barbara Ann; And Others

    In fall 1986, Mt. San Antonio College (MSAC) began a five year longitudinal study of the effectiveness of its matriculation services, which include assessment, orientation, counseling/advisement, and follow-up of students by staff members. The study utilized a computerized tracking system to compare retention, grade point average (GPA),…

  15. Mt. San Antonio College Matriculation Research Update, 1989-90.

    ERIC Educational Resources Information Center

    Hall, Barbara Ann; And Others

    In fall 1986, Mt. San Antonio College (MSAC) initiated a 5-year longitudinal study of the effectiveness of its matriculation services, including assessment, orientation, counseling/advisement, and follow-up. The academic performance and success of students participating in one or more of these services were compared to those of degree- and…

  16. Mt. San Antonio Community College Information Notebook; Volume Two, 1985.

    ERIC Educational Resources Information Center

    Mount San Antonio Community Coll. District, Walnut, CA.

    This databook contains some of the basic information to be used in decision making and planning in the Mt. San Antonio College (MSAC) District. Part I focuses on the demographic characteristics of the district population, feeder school districts, and data from other educational providers. Part II presents statewide data on potential enrollment by…

  17. Mt. St. Helens Seen Close Up on May 18.

    ERIC Educational Resources Information Center

    Stoffel, Dorothy B.; Stoffel, Keith L.

    1980-01-01

    Describes eruption steps in Mt. St. Helens' top surface deformation: constant shaking of earthquakes, minor steaming from vents, and sudden catastrophic eruption. Explosions caused black projectile-laden ash clouds, vertical white steam clouds, and vertical gray ash-laden clouds. (SK)

  18. 76 FR 35967 - Amendment of Class E Airspace; Bozeman, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-21

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Bozeman, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at... geographic coordinates for the Class D and E airspace areas, and updates the airport name. DATES:...

  19. 76 FR 53049 - Amendment of Class E Airspace; Shelby, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-25

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Shelby, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at... received. Class E airspace designations are published in paragraph 6005 of FAA Order 7400.9U dated...

  20. 77 FR 55690 - Amendment of Class E Airspace; Dillon, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... Federal Aviation Administration 14 CFR Part 71 Amendment of Class E Airspace; Dillon, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace... Federal Register a notice of proposed rulemaking (NPRM) to amend Class E airspace at Dillon...

  1. Southern Hemisphere Lidar Measurements of the Aerosol Clouds from Mt. Pinatubo and Mt. Hudson

    NASA Technical Reports Server (NTRS)

    Young, Stuart A.; Manson, Peter J.; Patterson, Graeme R.

    1992-01-01

    On 19 Jul., 1991, during tests to determine the ability of the newly-modified CSIRO Ns:YAG lidar to measure signals from the stratosphere before the arrival of dust from the eruption of Mt. Pinatubo, a strongly scattering layer was detected at an altitude of 2 km. That evening, the spectacular sunset and twilight were typical of volcanically disturbed conditions. Lidar measurements at 532 nm were made between 1400 and 1500 EST (0400-0500 UT) on 19 Jul. through broken cloud. Approximately 3800 laser firings were averaged in 256 shot blocks. These and subsequent data have been analyzed to produce profiles of aerosol volume backscatter function and scattering ratio. Clouds again prevented a clear view of the twilights on the next two nights, although there was some evidence for an enhanced glow. The evidence suggested that the aerosol layer had disappeared. An explanation for this disappearance and the earlier than expected arrival of the layer over Melbourne was required. Nimbus 7 TOMS data for 23 Jun. showed that the SO2 from the eruption had extended at least 11000 km to the west and that the southern boundary of the cloud had reached 15 degrees S just 8 days after the climactic eruption. It can be assumed that this cloud also contained dust and sulphuric acid aerosol. It was proposed that a section had then been broken away from the main cloud and carried south by a large scale eddy between the low latitude easterlies and the strong mid-latitude westerlies which finally carried the aerosol cloud over southern Australia. Accompanying 30 mb wind data showed a counter clockwise circulation, responsible for the transport, located in the South Atlantic Ocean.

  2. Transformation of MT Resistivity Sections into Geologically Meaningful Images

    NASA Astrophysics Data System (ADS)

    Park, S. K.

    2004-05-01

    Earthscope offers an unprecedented opportunity for interdisciplinary studies of North America. In addition to a continent-wide seismic study, it includes the acquisition of magnetotelluric (MT) data at many of the Bigfoot array sites. Earthscope will thus provide a uniform 3-D MT survey over regional scales when completed. MT interpreters will be able to include 3-D regional effects in their models for the first time whether they are interpreting local studies. However, the full value of the interdisciplinary nature of Earthscope will be realized only if MT sections and maps are useful to other earth scientists. The standard final product from any 2-D or 3-D MT interpretation is a spatial distribution of electrical resistivity. Inference of the physicochemical state from bulk resistivity is complicated because a variety of factors influence the property including temperature, intrinsic conduction of silicates, and small amounts of interconnected conducting materials (e.g., graphite, metallic minerals, partial melt, fluid). Here, I use petrophysical measurements and a petrological model to transform a resistivity section into cross sections of temperature and partial melt fraction in the mantle beneath the Sierra Nevada. In this manner, I am able to separate the contributions of increasing temperature and melt fraction to the bulk resistivity. Predicted melt fractions match observations from xenoliths relatively well but temperatures are systematically 200C higher than those observed. A small amount of dissolved hydrogen (~70 ppm H/Si) lowers the predicted temperatures to match those from the xenoliths, however. I conclude that while this transformation is a simple first step based on many assumptions, initial results are promising.

  3. New geophysical views of Mt.Melbourne Volcano (East Antarctica)

    NASA Astrophysics Data System (ADS)

    Armadillo, E.; Gambetta, M.; Ferraccioli, F.; Corr, H.; Bozzo, E.

    2009-05-01

    Mt. Melbourne volcano is located along the transition between the Transantarctic Mountains and the West Antarctic Rift System. Recent volcanic activity is suggested by the occurrence of blankets of pyroclastic pumice and scoria fall around the eastern and southern flanks of Mt Melbourne and by pyroclastic layers interbedded with the summit snows. Geothermal activity in the crater area of Mount Melbourne may be linked to the intrusion of dykes within the last 200 years. Geophysical networks suggest that Mount Melbourne is a quiescent volcano, possibly characterised by slow internal dynamics. During the 2002-2003 Italian Antarctic campaign a high-resolution aeromagnetic survey was performed within the TIMM (Tectonics and Interior of Mt. Melbourne area) project. This helicopter-borne survey was flown at low-altitude and in drape-mode configuration (305 m above terrain) with a line separation less than 500 m. Our new high-resolution magnetic maps reveal the largely ice-covered magmatic and tectonic patters in the Mt. Melbourne volcano area. Additionally, in the frame of the UK-Italian ISODYN-WISE project (2005-06), an airborne ice-sounding radar survey was flown. We combine the sub-ice topography with images and models of the interior of Mt. Melbourne volcano, as derived from the high resolution aeromagnetic data and land gravity data. Our new geophysical maps and models also provide a new tool to study the regional setting of the volcano. In particular we re-assess whether there is geophysical evidence for coupling between strike-slip faulting, the Terror Rift, and Mount Melbourne volcano.

  4. Analysis of BRCA1 and mtDNA haplotypes and mtDNA polymorphism in familial breast cancer.

    PubMed

    Gutiérrez Povedano, Cristina; Salgado, Josefa; Gil, Carmen; Robles, Maitane; Patiño-García, Ana; García-Foncillas, Jesús

    2015-04-01

    Mitochondrial DNA (mtDNA) defects have been postulated to play an important role in the modulation and/or progression of cancer. In the past decade, a wide spectrum of mtDNA variations have been suggested as potentially sensitive and specific biomarkers for several human cancer types. In this context, single nucleotide polymorphisms (SNPs) described as protective or risk variants have been published, in particular in breast cancer, though not without controversy. Moreover, many mtDNA haplogroups have been associated with different phenotypes and diseases. We genotyped 18 SNPs, 15 of them defining European mtDNA haplogroups, including SNPs described as protective or risk variants, 7 SNPs that determine BRCA1 haplotypes and a BRCA1 intron 7 polymorphism. We included in this study 90 Caucasian unrelated women with breast cancer with familial criteria and 96 controls. Our aim was to clarify the importance of any of these SNPs, mitochondrial haplogroups and BRCA1 haplotypes in the modulation of breast cancer. We detected no significant differences in the distribution of BRCA1 haplotypes between patients and controls. Haplogroup U and the 12308G variant of mtDNA were overrepresented within the control group (p = 0.005 and p = 0.036, respectively) compared to breast cancer. Finally, we identified a significant association between the BRCA1 intron 7 polymorphism and BRCA1 haplotypes. Specifically, (TTC)6/6 and (TTC)6/7 genotypes with the seven polymorphic site cassette of "H2-like" haplotypes, and the (TTC)7/7 genotype associated with the "H1-like" haplotypes (p < 0.001).

  5. Barley Metallothioneins: MT3 and MT4 Are Localized in the Grain Aleurone Layer and Show Differential Zinc Binding1[W][OA

    PubMed Central

    Hegelund, Josefine Nymark; Schiller, Michaela; Kichey, Thomas; Hansen, Thomas Hesselhøj; Pedas, Pai; Husted, Søren; Schjoerring, Jan Kofod

    2012-01-01

    Metallothioneins (MTs) are low-molecular-weight, cysteine-rich proteins believed to play a role in cytosolic zinc (Zn) and copper (Cu) homeostasis. However, evidence for the functional properties of MTs has been hampered by methodological problems in the isolation and characterization of the proteins. Here, we document that barley (Hordeum vulgare) MT3 and MT4 proteins exist in planta and that they differ in tissue localization as well as in metal coordination chemistry. Combined transcriptional and histological analyses showed temporal and spatial correlations between transcript levels and protein abundance during grain development. MT3 was present in tissues of both maternal and filial origin throughout grain filling. In contrast, MT4 was confined to the embryo and aleurone layer, where it appeared during tissue specialization and remained until maturity. Using state-of-the-art speciation analysis by size-exclusion chromatography inductively coupled plasma mass spectrometry and electrospray ionization time-of-flight mass spectrometry on recombinant MT3 and MT4, their specificity and capacity for metal ion binding were quantified, showing a strong preferential Zn binding relative to Cu and cadmium (Cd) in MT4, which was not the case for MT3. When complementary DNAs from barley MTs were expressed in Cu- or Cd-sensitive yeast mutants, MT3 provided a much stronger complementation than did MT4. We conclude that MT3 may play a housekeeping role in metal homeostasis, while MT4 may function in Zn storage in developing and mature grains. The localization of MT4 and its discrimination against Cd make it an ideal candidate for future biofortification strategies directed toward increasing food and feed Zn concentrations. PMID:22582132

  6. Legume Resources: MtDB and Medicago.Org.

    PubMed

    Retzel, Ernest F; Johnson, James E; Crow, John A; Lamblin, Anne F; Paule, Charles E

    2007-01-01

    To identify the genes and gene functions that underlie key aspects of legume biology, researchers have selected the cool season legume Medicago truncatula as a model system for legume research. The mission of the M. truncatula Consortium is to promote unrestricted sharing of data and information that are provided by Medicago research groups worldwide. Through integration of a variety of data and tools, the medicago.org site intends to facilitate progress in the fields of structural, comparative, and functional genomics. To this goal, and as a consortium partner, the Center for Computational Genomics and Bioinformatics (CCGB) at the University of Minnesota has developed MtDB2.0, the M. truncatula database version 2.0. The MtDB2.0 database is the first step toward the global integration of M. truncatula genomic, genetic, and biological information. MtDB2.0 is a relational database that integrates M. truncatula transcriptome data and provides a wide range of user-defined data mining options. The database is interrogated through a series of interfaces, with 58 options grouped into two filters. Sequence identifiers from all public M. truncatula sites [e.g., IDs from GenBank, CCGB, The Institute for Genomic Research (TIGR), National Center for Genome Resources (NCGR), and I'Institut National de la Recherche Agronomique (INRA)] are fully cross-referenced to facilitate comparisons between different sites, and hypertext links to the appropriate database records are provided for all queries' results. MtDB's goal is to provide researchers with the means to quickly and independently identify sequences that match specific research interests based on user-defined criteria. MtDB2.0 offers unrestricted access to advanced and powerful querying tools unmatched by any other public databases. Structurad Query Language (SQL)-encoded queries with a Java-based Web user interface, incorporate different filtering that allow sophisticated data mining of the expressed sequence tag sequencing

  7. 78 FR 38821 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... new airworthiness directive (AD) for Eurocopter France Model EC 155B, EC155B1, SA-366G1, SA-365N, SA... apply to Eurocopter France Model EC 155B, EC155B1, SA-366G1, SA-365N, SA-365N1, AS-365N2, and AS 365 N3..., 2011 (AD No. 2011-0190), to correct an unsafe condition for the Eurocopter France EC 155, SA 366,...

  8. [Current data on malaria in metropolitan France].

    PubMed

    Danis, M; Legros, F; Thellier, M; Caumes, E

    2002-01-01

    Epidemiological data from the French National Reference Center for Imported Diseases showed that the estimated number of cases of imported malaria in France increased from 5,940 in 1998 to 7,127 in 1999 and 8,056 in 2000. This three-year progression ended in 2001 when the number of estimated cases fell back to 7,223. It was due mainly to the concomitant increase in the number of people traveling to endemic zones especially in Africa. In 2000 the median age of patients with imported malaria in France was 29.5 years and the sex ratio was 1.78. Sixty-three percent of cases involved people of African origin and 37% involved "Westerners". The countries in which contamination occurred were located in tropical Africa (95%), Asia (2.2%), and Latin America (2.7%). During the three year period from 1998 to 2000, there were a total of 13 accidental autochtonous cases of malaria involving patients with no history of travel to tropical areas. The distribution of Plasmodium species involved in imported malaria in France was stable with 83% of cases involving Plasmodium falciparum, 6% involving Plasmodium vivax, 6.5% involving Plasmodium ovale and 1.3% involving Plasmodium malariae. Attacks were clinically uncomplicated in 90 to 95% of cases and severe in 2 to 5% including fatal Plasmodium falciparum malaria in 0.49 to 0.37% of cases. Less than 10% of the 45% of patients claiming use of prophylaxis complied properly. Analysis of the drugs used for curative treatment in 2000 showed an increase in the use of quinine and mefloquine and decrease in the use of halofantrine. The main objectives remain reduction of mortality and improvement of prevention.

  9. Outlier detection for groundwater data in France

    NASA Astrophysics Data System (ADS)

    Valmy, Larissa; de Fouquet, Chantal; Bourgine, Bernard

    2014-05-01

    Quality and quantity water in France are increasingly observed since the 70s. Moreover, in 2000, the EU Water Framework Directive established a framework for community action in the water policy field for the protection of inland surface waters (rivers and lakes), transitional waters (estuaries), coastal waters and groundwater. It will ensure that all aquatic ecosystems and, with regard to their water needs, terrestrial ecosystems and wetlands meet 'good status' by 2015. The Directive requires Member States to establish river basin districts and for each of these a river basin management plan. In France, monitoring programs for the water status were implemented in each basin since 2007. The data collected through these programs feed into an information system which contributes to check the compliance of water environmental legislation implementation, assess the status of water guide management actions (programs of measures) and evaluate their effectiveness, and inform the public. Our work consists in study quality and quantity groundwater data for some basins in France. We propose a specific mathematical approach in order to detect outliers and study trends in time series. In statistic, an outlier is an observation that lies outside the overall pattern of a distribution. Usually, the presence of an outlier indicates some sort of problem, thus, it is important to detect it in order to know the cause. In fact, techniques for temporal data analysis have been developed for several decades in parallel with geostatistical methods. However compared to standard statistical methods, geostatistical analysis allows incomplete or irregular time series analysis. Otherwise, tests carried out by the BRGM showed the potential contribution of geostatistical methods for characterization of environmental data time series. Our approach is to exploit this potential through the development of specific algorithms, tests and validation of methods. We will introduce and explain our method

  10. [Infant botulism in France, 1991-2009].

    PubMed

    King, L-A; Popoff, M-R; Mazuet, C; Espié, E; Vaillant, V; de Valk, H

    2010-09-01

    Infant botulism is caused by the ingestion of spores of Clostridium botulinum and affects newborns and infants under 12 months of age. Ingested spores multiply and produce botulinum toxin in the digestive tract, which then induces clinical symptoms. A single French case was described in the literature prior to 1991. We describe the cases of infant botulism identified in France between 1991 and 2009. All clinical suspicions of botulism must be declared in France. Biological confirmation of the disease is provided by the National reference laboratory for anaerobic bacteria and botulism at the Pasteur Institute. During this period, 7 cases of infant botulism were identified, 1 per year from 2004 to 2008 and 2 in 2009. The median age of affected infants was 119 days and all were female. All infants presented with constipation and oculomotor symptoms. All were hospitalized and required mechanical ventilation. The infants recovered from their botulism. The diagnosis of infant botulism was biologically confirmed for all patients. One 4-month-old infant was treated with a single dose of the human-derived botulism antitoxin specific for infant botulism types A and B (BabyBIG®). The infants all had different feeding habits ranging from exclusive breast feeding to a mix of formula feeding and solid food consumption. The consumption of honey, the only documented risk food for this disease, was reported for 3 of the infants. The honey had been placed on the pacifier of 2 infants and directly in the mouth of the 3rd by the mother. Infant botulism, a form of botulism that was previously rarely recognized in France, has been reported more frequently during the last 6 years. This disease remains rare but nonetheless severe. In light of recent epidemiological data, efforts to raise awareness among parents of infants and health professionals on the danger of infant botulism and particularly, its association with honey consumption seems necessary.

  11. How Gaz de France optimizes LNG regasification

    SciTech Connect

    Colonna, J.L.; Lecomte, B.; Caudron, S.

    1986-05-05

    A regasification optimization program was implemented at Montoir-de-Bretagne in 1984, and rapidly accepted by the operators. It has been an important tool for decision-making in the optimizing operation of this liquefied natural gas (LNG) storage and regasification terminal. The models used are regularly and easily updated on the basis of equipment behavior: aging or fouling. The Montoir-de-Bretagne LNG terminal is in the port area of Nates-Saint Nazaire on the Atlantic coast. It was commissioned in 1982 by Gaz de France. This terminal is used for receiving, storing, and regasifying the Algerian LNG received under a contract between Gaz de France and Sonatrach, as well as the LNG imported by Belgium and temporarily routed through France. It is designed to receive 25,000 to 200,000 cu m LNG carriers and has three 120,000 cm m LNG storage tanks. The daily sendout ranges between 6.7 million cu m and 36 million cu m. Monitor terminal supplies mainly Brittany and the Paris area. Two identifical berths allow the simultaneous reception of two LNG carriers. LNG is carried to the storage tanks in 32-in. lines at a rate of 12,000 cu m/hr. Each storage tank is equipped with three submerged 450 cu m/hr pumps with which the LNG is sent from the tanks to the secondary pumps at 8 bar. The nine high-pressure (HP) secondary pumps, with a capacity of either 450 cu m/hr or 180 cu m/hr, raise the LNG pressure to a level at least equal to pipeline pressure prior to revaporization.

  12. [National organization of forensic medicine in France].

    PubMed

    Chariot, Patrick

    2012-06-01

    Forensic medicine has long been characterized, in France, by diverse medical practices, which affected its recognition and development. A change was needed, Harmonization procedure includes the development of professional guidelines and allows forensic medicine to look at itself. However, the implementation of the recommendations is still far from complete. A national reform came into effect on 15 January 2011 and has defined a national reform of forensic medicine which includes funding by global budgets instead of fee-for-service. This reform allows easier organization and identification of forensic medicine units. One year later, tangible results are mixed. Forensic medicine is now more clearly identified but properly defined funding criteria are still lacking.

  13. [Economic repercussions of cardiac insufficiency in France].

    PubMed

    Selke, B; Brunot, A; Lebrun, T

    2003-03-01

    The aim of the article is to review economic and public health consequences of congestive heart failure in France. This disease with an increasing prevalence induces for the social security system and the society a high cost; 85 to 93% of this cost are bound to hospitalizations, most of them avoidable. New modalities of care are to be chosen in order to improve the management of heart failure and to contain costs. In this context, multidisciplinary interventions based on patients' education are experimented taking care to assure a greater role to health actors working in the ambulatory sector (GPs, private cardiologists, nurses).

  14. Frances E. Jensen's The Teenage Brain.

    PubMed

    Silveri, Marisa M

    2015-01-01

    The unpredictable and sometimes incomprehensible moods and behaviors of a teenager can be a head-scratching mystery-especially to parents. Hormones, boredom, social media, peer pressure, and drugs and alcohol are just a few of the factors to consider. Frances E. Jensen, M.D., professor and chair of neurology at the University of Pennsylvania and the mother of two sons who are now in their twenties (along with Washington Post health and science reporter and Pulitzer Prize winner Amy Ellis Nutt) look at the emerging science of the adolescent brain and provide advice based on Jensen's own research and experience as a single mother.

  15. La France a ta porte: Negocier les apprentissages (France at Your Doorstep: Negotiating Learning Experiences).

    ERIC Educational Resources Information Center

    de Acosta, Asuncion; Serna, Isabel

    1992-01-01

    A second-language teaching strategy in which students are active in the selection of a unit theme and objective is discussed. In this approach, the teacher assumes the role of monitor in student development of the unit. A sample unit on language for daily living in France illustrates the process. (MSE)

  16. Attention to surfaces modulates motion processing in extrastriate area MT.

    PubMed

    Wannig, Aurel; Rodríguez, Valia; Freiwald, Winrich A

    2007-05-24

    In the visual system, early atomized representations are grouped into higher-level entities through processes of perceptual organization. Here we present neurophysiological evidence that a representation of a simple object, a surface defined by color and motion, can be the unit of attentional selection at an early stage of visual processing. Monkeys were cued by the color of a fixation spot to attend to one of two transparent random-dot surfaces, one red and one green, which occupied the same region of space. Motion of the attended surface drove neurons in the middle temporal (MT) visual area more strongly than physically identical motion of the non-attended surface, even though both occurred within the spotlight of attention. Surface-based effects of attention persisted even without differential surface coloring, but attentional modulation was stronger with color. These results show that attention can select surface representations to modulate visual processing as early as cortical area MT.

  17. Microtron MT 25 as a source of neutrons

    SciTech Connect

    Kralik, M.; Solc, J.; Chvatil, D.; Krist, P.; Turek, K.; Granja, C.

    2012-08-15

    The objective was to describe Microtron MT25 as a source of neutrons generated by bremsstrahlung induced photonuclear reactions in U and Pb targets. Bremsstrahlung photons were produced by electrons accelerated at energy 21.6 MeV. Spectral fluence of the generated neutrons was calculated with MCNPX code and then experimentally determined at two positions by means of a Bonner spheres spectrometer in which the detector of thermal neutrons was replaced by activation Mn tablets or track detectors CR-39 with a {sup 10}B radiator. The measured neutron spectral fluence and the calculated anisotropy served for the estimation of neutron yield from the targets and for the determination of ambient dose equivalent rate at the place of measurement. Microtron MT25 is intended as one of the sources for testing neutron sensitive devices which will be sent into the space.

  18. MT Serpentis: A pre-cataclysmic variable or not?

    NASA Astrophysics Data System (ADS)

    Bruch, A.

    2002-01-01

    MT Ser, the central star of the planetary nebula Abell 41, shows photometric variations with a period of P1 = 2h 43m (Grauer & Bond 1983, ApJ, 271, 259). They are interpreted as due to a reflection effect in a close binary consisting of a compact hot component and a cool star (Model 1). This configuration would make MT Ser the pre-cataclysmic variable with the shortest known orbital period. However, an alternative scenario of a system consisting of two hot subdwarfs in an orbit with period P2 = 2 P1 is also possible (Model 2). The light curve can then be explained by ellipsoidal variations and (partial) eclipses.

  19. 78 FR 52112 - Proposed Amendment of Class E Airspace; Cut Bank, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; Cut Bank, MT AGENCY... action proposes to modify Class E airspace at Cut Bank Municipal Airport, Cut Bank, MT. Controlled... from 700/1,200 feet above the surface at Cut Bank Municipal Airport, Cut Bank, MT. Controlled...

  20. Random Genetic Drift Determines the Level of Mutant mtDNA in Human Primary Oocytes

    PubMed Central

    Brown, D. T.; Samuels, D. C.; Michael, E. M.; Turnbull, D. M.; Chinnery, P. F.

    2001-01-01

    We measured the proportion of mutant mtDNA (mutation load) in 82 primary oocytes from a woman who harbored the A3243G mtDNA mutation. The frequency distribution of mutation load indicates that random drift is the principal mechanism that determines the level of mutant mtDNA within individual oocytes. PMID:11133360

  1. 78 FR 54415 - Proposed Establishment of Class E Airspace; Ennis, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ...). SUMMARY: This action proposes to establish Class E airspace at Ennis- Big Sky Airport, Ennis, MT... System (GPS) standard instrument approach procedures at Ennis-Big Sky Airport, Ennis, MT. The FAA is... from 700 feet above the surface within a 7-mile radius of Ennis- Big Sky Airport, Ennis, MT, along...

  2. Directions toward the Year 2000. Strategic Plan, Mt. San Antonio Community College.

    ERIC Educational Resources Information Center

    Mount San Antonio Community Coll. District, Walnut, CA.

    This booklet presents Mt. San Antonio College's (Mt. SAC's) long-range goals and specific action priorities in an effort to focus planning on the year 2000. Introductory comments discuss the purpose of strategic planning and Mt. SAC's planning orientation. The next sections list goals and objectives with respect to: (1) the improvement of existing…

  3. 77 FR 41939 - Proposed Establishment of Class E Airspace; Deer Lodge, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-17

    ... Proposed Establishment of Class E Airspace; Deer Lodge, MT AGENCY: Federal Aviation Administration (FAA... airspace at Deer Lodge-City-County Airport, Deer Lodge, MT. Controlled airspace is necessary to accommodate... procedures at Deer Lodge-City-County Airport, Deer Lodge, MT. The FAA is proposing this action to enhance...

  4. An Analysis of the Mt. Meron Seismic Array

    SciTech Connect

    Pasyanos, M E; Ryall, F

    2008-01-10

    We have performed a quick analysis of the Mt. Meron seismic array to monitor regional seismic events in the Middle East. The Meron array is the only current array in the Levant and Arabian Peninsula and, as such, might be useful in contributing to event location, identification, and other analysis. Here, we provide a brief description of the array and a review of the travel time and array analysis done to assess its performance.

  5. miRNAs in mtDNA-less cell mitochondria

    PubMed Central

    Dasgupta, N; Peng, Y; Tan, Z; Ciraolo, G; Wang, D; Li, R

    2015-01-01

    The novel regulation mechanism in mtDNA-less cells was investigated. Very low mtDNA copy in mtDNA-less 206 ρ° cells was identified. But no 13 mitochondria-specific proteins were translated in 206 ρ° cells. Their mitochondrial respiration complexes V, III and II were 86.5, 29.4 and 49.6% of 143B cells, respectively. Complexes I and IV completely lack in 206 ρ° cells. Non-mitochondrial respiration to generate ATP in 206 ρ° cells was discovered. The expression levels of some mitochondrial RNAs including 12S rRNA, COX1, COX2, COX3, ND4 and ND5 were low. However, ND1, ND3 and Cyto b were not expressed in 206 ρ° cells. Unequal transcription of mitochondrial RNAs indicated the post-transcriptional cleavage and processing mechanisms in the regulation of mitochondrial gene expression in 206 ρ° cells. MicroRNAs (miRNAs) may modulate these mitochondrial RNA expression in these cells. RNA-induced silencing complex indeed within 206 ρ° cell mitochondria indicated miRNAs in 206 ρ° cell mitochondria. miRNA profile in mtDNA-less 206 ρ° cells was studied by next-generation sequencing of small RNAs. Several mitochondria-enriched miRNAs such as miR-181c-5p and miR-146a-5p were identified in 206 ρ° cell mitochondria. miR-181c-5p and miR-146a-5p had 23 and 19 potential targets on mitochondrial RNAs respectively, and these two miRNAs had multiple targets on mitochondria-associated messenger RNAs encoded by nuclear genes. These data provided the first direct evidence that miRNAs were imported into mitochondria and regulated mitochondrial RNA expressions. PMID:27551440

  6. Volcanogenic origin of cenotes near Mt Gambier, southeastern Australia

    NASA Astrophysics Data System (ADS)

    Webb, John A.; Grimes, Ken G.; Lewis, Ian D.

    2010-07-01

    The cenotes near Mt Gambier are circular, cliffed, collapse dolines containing water-table lakes up to 125 m deep, floored by large rubble cones. They lie in a flat, coastal plain composed of mid-Tertiary limestone. Most of the deepest cenotes are concentrated in two small areas located along trends sub-parallel to the main joint direction in the limestone. The cenotes do not connect to underwater phreatic passages, and water chemistry data confirm that they are not part of an interconnected karst network. They formed by collapse into large chambers (up to > 1 million m 3) that extended 125 m or more below the land surface. Several cenotes have actively growing stromatolites on the sub-vertical walls that started growing at ˜ 8000 years BP. The caves that collapsed to form the deep Mt Gambier cenotes are much larger than shallow and deep phreatic caves in the area, and do not connect into deep phreatic systems. They were not formed by freshwater/seawater mixing, responsible for many of the well-known Yucatan cenotes, because they are not associated with locations of the mixing zone during previous high sea levels, and are much larger than caves presently forming along the mixing zone near Mt Gambier. Instead dissolution was most likely due to a process whereby acidified groundwater containing large amounts of volcanogenic CO 2 ascended up fractures from the magma chambers that fed the Pleistocene-Holocene volcanic eruptions in the area; deep reservoirs of volcanogenic CO 2 occur nearby. Cave dissolution could have been due to release of CO 2 during the Mt Gambier eruption ˜ 28,000 years ago, followed by collapse to form cenotes during the low sea levels of the Last Glacial Maximum ˜ 20,000 years ago. The cenotes then flooded ˜ 8000 years ago as sea level rose, and stromatolites began to grow on the walls.

  7. Vertical Scales of Turbulence at the Mt. Wilson Observatory

    NASA Technical Reports Server (NTRS)

    Treuhaft, Robert N.

    1995-01-01

    The vertical scales of turbulence at the Mt. Wilson observatory are inferred from data from the University of California at Berkeley Infrared Spatial Interferometer (ISI), by modeling path length fluctuations observed in the interferometric paths to celestial objects and those in instrumental ground- based paths. The correlations between the stellar and ground-based path length fluctuations and the temporal statistic of those fluctuations are modeled on various time scales to constrain the vertical scales.

  8. Evidences for higher nocturnal seismic activity at the Mt. Vesuvius

    NASA Astrophysics Data System (ADS)

    Mazzarella, Adriano; Scafetta, Nicola

    2016-07-01

    We analyze hourly seismic data measured at the Osservatorio Vesuviano Ovest (OVO, 1972-2014) and at the Bunker Est (BKE, 1999-2014) stations on the Mt. Vesuvius. The OVO record is complete for seismic events with magnitude M ≥ 1.9. We demonstrate that before 1996 this record presents a daily oscillation that nearly vanishes afterwards. To determine whether a daily oscillation exists in the seismic activity of the Mt. Vesuvius, we use the higher quality BKE record that is complete for seismic events with magnitude M ≥ 0.2. We demonstrate that BKE confirms that the seismic activity at the Mt. Vesuvius is higher during nighttime than during daytime. The amplitude of the daily oscillation is enhanced during summer and damped during winter. We speculate possible links with the cooling/warming diurnal cycle of the volcanic edifice, with external geomagnetic field and with magnetostriction, which stress the rocks. We find that the amplitude of the seismic daily cycle changes in time and has been increasing since 2008. Finally, we propose a seismic activity index to monitor the 24-hour oscillation that could be used to complement other methodologies currently adopted to determine the seismic status of the volcano to prevent the relative hazard.

  9. Geothermal energy resource investigations at Mt. Spurr, Alaska

    SciTech Connect

    Turner, D.L.; Wescott, E.M.

    1986-12-01

    Spurr volcano is a composite Quaternary cone of largely andesitic composition located on the west side of Cook Inlet about 80 miles west of Anchorage and about 40 miles from the Beluga electrical transmission line. Geologic mapping (Plate 1-1) shows that the present summit depression was produced by a Mt. St. Helens-type sector collapse, rather than by a caldera collapse. Geochronologic and previous tephrachronologic studies show that there has been an active magmatic system at Spurr volcano during the late Pleistocene-to-Holocene time interval that is of critical interest for geothermal energy resource assessment. Major effort was devoted to geochemical and geophysical surveys of the accessible area south of Mt. Spurr, in addition to geologic mapping and geochronologic studies. Many coincident mercury and helium anomalies were found, suggesting the presence of geothermal systems at depth. Extremely large electrical self-potential anomalies were also found, together with extensive zones of low resistivity discovered by our controlled-source audiomagnetotelluric survey. The juxtaposition of all of these different types of anomalies at certain areas on the south slope of Crater Peak indicates the presence of a geothermal system which should be accessible by drilling to about 2000 ft depth. It is also evident that there is a strong volcanic hazard to be evaluated in considering any development on the south side of Mt. Spurr. This hazardous situation may require angle drilling of production wells from safer areas and placement of power generation facilities at a considerable distance from hazardous areas.

  10. Strategic nuclear forces of Britain and France

    SciTech Connect

    Prados, J.; Wit, J.S.; Zagurek, M.J. Jr.

    1984-08-01

    Weapon inventories of the US and the USSR account for about 97% of the nuclear warheads in the world today; Britain and France have most of the remainder. Yet even the comparatively modest claims the two Western European nations can make in this regard represent an awesome military capability that the USSR (and, to a lesser extent, the US) cannot afford to ignore. Indeed, the recent proposals both superpowers have made to dismantle all their European-based intermediate-range missiles differ sharply in particulars but raise the same fundamental question: What role will the other nuclear forces in Europe have in the future military balance. The Europeans are unlikely to place their limited strategic forces on the bargaining table along with those of the USSR and the US unless the superpowers impose severe constraints on their own strategic-weapon programs, and in particular on their strategic-defense programs. The deployment of such defense systems poses a worrisome dilemma for the Europeans: while in the near term a Soviet anti-ballistic-missile (ABM) system might have only marginal military impact, over the longer term a novel, exotic defense could conceivably nullify the dependent deterrent Britain and France have so arduously sought. At the same time and American system such as the Strategic Defense Initiative could, by decoupling the defense of Europe from that of the US, increase the need for precisely such an independent deterrent in the minds of the British and the French.

  11. Aedes albopictus: a potential problem in France.

    PubMed

    Rodhain, F

    1995-12-01

    Aedes albopictus, a mosquito of Asian origin, has been rapidly spreading in all the continents since a decade: it is now established in North and South America, Africa, Oceania and even in Europe where it was detected in Albania, 1979 and in Italy, 1990. The international shipping trade of used tires provides to Ae. albopictus an ideal mechanism of dissemination, and everywhere the tire stocks constitute an extremely productive ecological niche. Now, this mosquito is present in several localities in Northern and Central Italy, and it is a real threat for other Mediterranean countries, particularly Southern part of France (French Riviera and Corsica) where climatic conditions are very suitable for its establishment. In addition, the tolerance exhibited by some natural populations of Ae. albopictus for low temperatures allows this species to occupy an area much further north than Ae. aegypti. Ae. albopictus is a very competent vector for many arboviruses, particularly the four dengue serotypes, with the possibility of a vertical transmission; we also know that it can act as an experimental vector for many other viruses. The consequences of its introduction into France would lie in an increased level of transmission of autochthonous viral or filarial (canine dirofilariasis) infections, along with the spread of viruses presently unknown in the region (like dengue, Rift Valley fever, Batai, etc.). For these reasons, it is necessary to set up a permanent entomological surveillance in all the threatened areas in order to detect immediately such an introduction and to be able to quickly eliminate the mosquito.

  12. Overview of manure treatment in France.

    PubMed

    Loyon, L

    2017-03-01

    Manure treatment becomes a focal issue in relation to current EU and national policies on environmental, climate and renewable energy matters. The objective of this desk study was to collect all available data on the treatment of manure from cattle, pig and poultry farms for an overview of manure treatment in France. Specific surveys in 2008 showed that 12% of pig farms, 11% of poultry farms and 7.5% of cattle farms was concerned by manure treatment. Taken together, the treatment of pig, poultry and cattle manure accounted for 13.6milliontons corresponding to 11.3% of the total annual tonnage (120milliontons). The main processes, mostly applied on the farm, were composting (8.5milliontons), aerobic treatment (2.9milliontons of pig slurry) and anaerobic digestion (1milliontons). Other manure treatments, including physical-chemical treatment, were less frequent (0.4million of m(3)). Treated manure was mainly used to fertilize the soil and crops on the farm concerned. Manure treatment can thus be considered to be underused in France. However, anaerobic digestion is expected to expand to reach the European target of 20% of energy from renewable sources. Nevertheless, this expansion will depend on overcoming the constraint requiring registration or normalization of the use of the digestate as fertilizer. Thus, to avoid penalizing farmers, the further development or creation of collective processing platforms is recommended, combined with an N recovery process that will enable the production of organic amendments and fertilizers in an easy marketable form.

  13. 75 FR 43556 - TA-W-73,381, MT Rail Link, Inc., Missoula, MT; TA-W-73,381A, Billings, MT; TA-W-73,381B, Laurel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... Employment and Training Administration TA-W-73,381, MT Rail Link, Inc., Missoula, MT; TA-W-73,381A, Billings... facilities (yards) in Billings, Laurel, Livingston, Helena and Missoula, Montana. The Billings, Laurel... Rail Link, Inc. at facilities in Billings, Laurel, Livingston, and Helena, Montana. The amended...

  14. Causes and Consequences of Rapidly Evolving mtDNA in a Plant Lineage

    PubMed Central

    Trapp, Paul; Miller, Christopher M.; Bazos, Ioannis

    2017-01-01

    Understanding mechanisms of coevolution between nuclear and mitochondrial (mt) genomes is a defining challenge in eukaryotic genetics. The angiosperm genus Silene is a natural system to investigate the causes and consequences of mt mutation rate variation because closely related species have highly divergent rates. In Silene species with fast-evolving mtDNA, nuclear genes that encode mitochondrially targeted proteins (N-mt genes) are also fast-evolving. This correlation could indicate positive selection to compensate for mt mutations, but might also result from a recent relaxation of selection. To differentiate between these interpretations, we used phylogenetic and population-genetic methods to test for positive and relaxed selection in three classes of N-mt genes (oxidative phosphorylation genes, ribosomal genes, and “RRR” genes involved in mtDNA recombination, replication, and repair). In all three classes, we found that species with fast-evolving mtDNA had: 1) elevated dN/dS, 2) an excess of nonsynonymous divergence relative to levels of intraspecific polymorphism, which is a signature of positive selection, and 3) no clear signals of relaxed selection. “Control” genes exhibited comparatively few signs of positive selection. These results suggest that high mt mutation rates can create selection on N-mt genes and that relaxed selection is an unlikely cause of recent accelerations in the evolution of N-mt genes. Because mt-RRR genes were found to be under positive selection, it is unlikely that elevated mt mutation rates in Silene were caused by inactivation of these mt-RRR genes. Therefore, the causes of extreme increases in angiosperm mt mutation rates remain uncertain. PMID:28164243

  15. Adjusting MtDNA Quantification in Whole Blood for Peripheral Blood Platelet and Leukocyte Counts

    PubMed Central

    Gonzalez-Lazaro, Monica; Moreno-Loshuertos, Raquel; Fernandez-Silva, Patricio; Enriquez, Jose Antonio; Laclaustra, Martin

    2016-01-01

    Alterations of mitochondrial DNA copy number (mtDNAcn) in the blood (mitochondrial to nuclear DNA ratio) appear associated with several systemic diseases, including primary mitochondrial disorders, carcinogenesis, and hematologic diseases. Measuring mtDNAcn in DNA extracted from whole blood (WB) instead of from peripheral blood mononuclear cells or buffy coat may yield different results due to mitochondrial DNA present in platelets. The aim of this work is to quantify the contribution of platelets to mtDNAcn in whole blood [mtDNAcn(WB)] and to propose a correction formula to estimate leukocytes' mtDNAcn [mtDNAcn(L)] from mtDNAcn(WB). Blood samples from 10 healthy adults were combined with platelet-enriched plasma and saline solution to produce artificial blood preparations. Aliquots of each sample were combined with five different platelet concentrations. In 46 of these blood preparations, mtDNAcn was measured by qPCR. MtDNAcn(WB) increased 1.07 (95%CI 0.86, 1.29; p<0.001) per 1000 platelets present in the preparation. We proved that leukocyte count should also be taken into account as mtDNAcn(WB) was inversely associated with leukocyte count; it increased 1.10 (95%CI 0.95, 1.25, p<0.001) per unit increase of the ratio between platelet and leukocyte counts. If hematological measurements are available, subtracting 1.10 the platelets/leukocyte ratio from mtDNAcn(WB) may serve as an estimation for mtDNAcn(L). Both platelet and leukocyte counts in the sample are important sources of variation if comparing mtDNAcn among groups of patients when mtDNAcn is measured in DNA extracted from whole blood. Not taking the platelet/leukocyte ratio into account in whole blood measurements, may lead to overestimation and misclassification if interpreted as leukocytes' mtDNAcn. PMID:27736919

  16. Social Representation of Gifted Children: A Preliminary Study in France

    ERIC Educational Resources Information Center

    Tavani, Jean Louis; Zenasni, Franck; Pereira-Fradin, Maria

    2009-01-01

    There is a growing recognition of giftedness in France and the need for identification. Social Representations (SR) of gifted children have never been examined in France with an appropriate methodology, yet it is important to do so as the information obtained may help ensure the insertion and inclusion of these children in school and society. The…

  17. In Wake of Riots, France Refashions Priority Zones

    ERIC Educational Resources Information Center

    Hendrie, Caroline

    2006-01-01

    This article deals with an initiative embarked upon by the government of France one year after widespread youth violence broke out in many disadvantaged communities in France. The initiative is aimed at adapting its 25-year-old "priority education" program to a landscape that has dramatically changed. The initiative is the centerpiece of…

  18. France: The Challenges of Renewal. Headline Series #282.

    ERIC Educational Resources Information Center

    DePorte, A. W.

    France has responded well to the social, economic, and political challenges which began when that nation was defeated by Germany in 1940. Two major challenges have been to limit internal quarrels which reduce the nation's ability to handle current issues and to accept the fact that France is no longer the greatest power in Europe. Chapter 1…

  19. France: The Move toward Distance Education in the University Sector

    ERIC Educational Resources Information Center

    Mortimer, Peter

    2005-01-01

    France is one of the most modern countries in the world and is a leading force in Europe. A highly literate and well-educated society, France's education statistics for 2003 show 12.1 million French children in primary and secondary education and 2.2 million students in tertiary education. The concept of education as a market commodity--long since…

  20. La punaise diabolique a la conquete de la France

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Halyomorpha halys is now present in France in Alsace and in several neighboring countries (Switzerland and Italy). The potential risk of invasion of H. halys throughout France is considered to be high. Through its natural dispersal, or with human assistance, this insect will likely colonize the majo...

  1. A Primer for Accompanying Secondary Student Groups to France. [Revised].

    ERIC Educational Resources Information Center

    Becker, Jim

    Many of the factors that can help ensure a successful and positive learning experience for teachers, leaders, chaperons, and students who travel and/or study in France are addressed in this publication. Although it is geared toward France, many of the ideas, especially the section on pre-departure orientation, can be applied to any travel group.…

  2. The Challenges Facing Catholic Education in France Today

    ERIC Educational Resources Information Center

    Moog, François

    2016-01-01

    The effects of secularisation on society demand a rethinking of the identity and mission of Catholic schools in France. In 2013, the French bishops published a new directory which offers new approaches, described here, based on the three challenges facing Catholic education in France: linking social responsibility and evangelisation, setting up…

  3. Influenza D Virus in Cattle, France, 2011–2014

    PubMed Central

    Pelletier, Claire; Meyer, Gilles

    2015-01-01

    A new influenza virus, genus D, isolated in US pigs and cattle, has also been circulating in cattle in France. It was first identified there in 2011, and an increase was detected in 2014. The virus genome in France is 94%–99% identical to its US counterpart, which suggests intercontinental spillover. PMID:25628038

  4. 78 FR 49116 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-13

    ...-018-AD; Amendment 39-16847; AD 2011-22-05] RIN 2120-AA64 Airworthiness Directives; Eurocopter France... applies to certain Eurocopter France (Eurocopter) Model AS350B, B1, B2, B3, BA, C, D, and D1...

  5. International Reports on Literacy Research: France and Argentina

    ERIC Educational Resources Information Center

    Malloy, Jacquelynn A., Comp.; Botzakis, Stergios, Comp.

    2006-01-01

    This is a compilation of two separate reports on international literacy research from France and Argentina. In the reports from France, research correspondent Jacques Fijalkow detailed three research projects that included the following: (1) A description of adult literacy skills; (2) An investigation of how study-abroad students were integrated…

  6. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  7. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  8. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  9. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  10. 47 CFR 3.46 - Use of gold francs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false Use of gold francs. 3.46 Section 3.46... AUTHORITIES IN MARITIME AND MARITIME MOBILE-SATELLITE RADIO SERVICES Settlement Operations § 3.46 Use of gold francs. An accounting authority must accept accounts presented to it from foreign administrations in...

  11. [Training in tropical medicine in France].

    PubMed

    Touze, Jean-Étienne; Laroche, Roland

    2013-10-01

    Tropical medicine was a key element of the medical structures provided by France to our former colonies and, later; to countries within the scope of our international cooperation. hI recent decades, France has drastically reduced its bilateral commitments to countries in the tropics, and especially in sub-Saharan Africa. At the same time, the teaching of tropical medicine, which was highly regarded even beyond our borders, has lost a good deal of its expertise. Initially available in a few large French centers, and ensured by teachers with extensive field experience, training in tropical medicine is now offered in many universities. However; their programs and educational objectives, focusing mainly on infectious and parasitic diseases, no longer meet the healthcare priorities of southern countries, which are facing an epidemiological transition and the rise of non communicable diseases. Few teachers now have recognized expertise in tropical medicine. These changes have had negative consequences for research programs in tropical medicine and for the image of French assistance to developing countries. In this context, the followving perspectives should be considered: 1) training in tropical medicine should be enhanced by the creation of a national diploma recognized by international bodies. 2) The creation of a doctoral course in tropical medicine is a prerequisite for achieving this goal, and the future diploma must include a significant research component. 3) Teaching in tropical medicine must become more practical and be ensured by teachers with extensive field experience. 4) Training in tropical medicine should be part of a bilateral relationship with countries in the tropics, each party contributing its expertise while respecting that of its partners. 5) Training in tropical medicine should be backed uip by high-level scientific research based on enhanced synergy of our current networks (Institute for Research and Development, Network of overseas Pasteur

  12. Repetitive transcranial magnetic stimulation of human MT+ reduces apparent motion perception.

    PubMed

    Matsuyoshi, Daisuke; Hirose, Nobuyuki; Mima, Tatsuya; Fukuyama, Hidenao; Osaka, Naoyuki

    2007-12-18

    We investigated the effects of repetitive transcranial magnetic stimulation (rTMS) over the human cerebral cortex on apparent motion perception. Previous studies have shown that human extrastriate visual area MT+ (V5) processes not only real but also apparent motion. However, the functional relevance of MT+ on long-range apparent motion perception remains unclear. Here, we show direct evidence for the involvement of MT+ in apparent motion perception using rTMS, which is known to temporarily inhibit a localized region in the cerebral cortex. The results showed that apparent motion perception decreased after applying rTMS over MT+, but not after applying rTMS over the control region (inferior temporal gyrus). The decrease in performance caused by applying rTMS to MT+ suggests that MT+ is a causally responsible region for apparent motion perception, and thus, further supports the idea that MT+ plays a major role in the perception of motion.

  13. An enhanced MITOMAP with a global mtDNA mutational phylogeny

    PubMed Central

    Ruiz-Pesini, Eduardo; Lott, Marie T.; Procaccio, Vincent; Poole, Jason C.; Brandon, Marty C.; Mishmar, Dan; Yi, Christina; Kreuziger, James; Baldi, Pierre; Wallace, Douglas C.

    2007-01-01

    The MITOMAP () data system for the human mitochondrial genome has been greatly enhanced by the addition of a navigable mutational mitochondrial DNA (mtDNA) phylogenetic tree of ∼3000 mtDNA coding region sequences plus expanded pathogenic mutation tables and a nuclear-mtDNA pseudogene (NUMT) data base. The phylogeny reconstructs the entire mutational history of the human mtDNA, thus defining the mtDNA haplogroups and differentiating ancient from recent mtDNA mutations. Pathogenic mutations are classified by both genotype and phenotype, and the NUMT sequences permits detection of spurious inclusion of pseudogene variants during mutation analysis. These additions position MITOMAP for the implementation of our automated mtDNA sequence analysis system, Mitomaster. PMID:17178747

  14. Aging in france: population trends, policy issues, and research institutions.

    PubMed

    Béland, Daniel; Viriot Durandal, Jean-Philippe

    2013-04-01

    Like in other advanced industrial countries, in France, demographic aging has become a widely debated research and policy topic. This article offers a brief overview of major aging-related trends in France. The article describes France's demographics of aging, explores key policy matters, maps the institutional field of French social gerontology research, and, finally, points to several emerging issues about aging. In France, these issues include active and healthy aging, the improvement of knowledge on specific vulnerable segments of the elderly population, and the adaptation of the urban landscape and infrastructure to an aging population. At the broadest level, one of the key points formulated in this article is that in France, aging research is dominated by the state, yet it is scattered and compartmentalized, posing a crucial challenge in an era dominated by European and other international networks and coordination efforts in aging policy and knowledge.

  15. MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27

    PubMed Central

    Pai, Hui Chen; Kumar, Sunil; Shen, Chien-Chang; Liou, Jing Ping; Pan, Shiow Lin; Teng, Che Ming

    2015-01-01

    Objective In this study, the anticancer mechanisms of MT-4 were examined in A2780 and multidrug-resistant NCI-ADR/res human ovarian cancer cell lines. Methods To evaluate the activity of MT-4, we performed in vitro cell viability and cell cycle assays and in vivo xenograft assays. Immunoblotting analysis was carried out to evaluate the effect of MT-4 on ovarian cancer. Tubulin polymerization was determined using a tubulin binding assay. Results MT-4 (2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-phenol), a derivative of moscatilin, can inhibit both sensitive A2780 and multidrug-resistant NCI-ADR/res cell growth and viability. MT-4 inhibited tubulin polymerization to induce G2/M arrest followed by caspase-mediated apoptosis. Further studies indicated that MT-4 is not a substrate of P-glycoprotein (p-gp). MT-4 also caused G2/M cell cycle arrest, accompanied by the upregulation of cyclin B, p-Thr161 Cdc2/p34, polo-like kinase 1 (PLK1), Aurora kinase B, and phospho-Ser10-histone H3 protein levels. In addition, we found that p38 MAPK pathway activation was involved in MT-4-induced apoptosis. Most importantly, MT-4 also decreased heat shock protein 27 expression and reduced its interaction with caspase-3, which inured cancer cells to chemotherapy resistance. Treatment of cells with SB203580 or overexpression of dominant negative (DN)-p38 or wild-type HSP27 reduced PARP cleavage caused by MT-4. MT-4 induced apoptosis through regulation of p38 and HSP27. Our xenograft models also show the in vivo efficacy of MT-4. MT-4 inhibited both A2780 and NCI-ADR/res cell growth in vitro and in vivo. Conclusion These findings indicate that MT-4 could be a potential lead compound for the treatment of multidrug-resistant ovarian cancer. PMID:25874627

  16. The LUNEX5 project in France

    NASA Astrophysics Data System (ADS)

    Couprie, M. E.; Benabderrahmane, C.; Betinelli, P.; Bouvet, F.; Buteau, A.; Cassinari, L.; Daillant, J.; Denard, J. C.; Eymard, P.; Gagey, B.; Herbeaux, C.; Labat, M.; Lagarde, B.; Lestrade, A.; Loulergue, A.; Marchand, P.; Marlats, J. L.; Miron, C.; Morin, P.; Nadji, A.; Polack, F.; Pruvost, J. B.; Ribeiro, F.; Ricaud, J. P.; Roy, P.; Tanikawa, T.; Roux, R.; Bielawski, S.; Evain, C.; Szwaj, C.; Lambert, G.; Lifschitz, A.; Malka, V.; Lehe, R.; Rousse, A.; Phuoc, K. Ta; Thaury, C.; Devanz, G.; Luong, M.; Carré, B.; LeBec, G.; Farvacque, L.; Dubois, A.; Lüning, J.

    2013-03-01

    The LUNEX5 (free electron Laser Using a New accelerator for the Exploitation of X-ray radiation of 5th generation) in France aims at investigating the generation of short, intense, and coherent pulses in the soft x-ray region (with two particular targeted wavelengths of 20 and 13 nm). It consists in a single Free Electron Laser (FEL) line with cryo-ready in-vacuum undulators using a Conventional Linear Accelerator (CLA) using the superconducting technology of 400 MeV or a Laser Wake Field Accelerator (LWFA) ranging from 0.4 to 1 GeV with multi-TW or PW lasers. The FEL line can be operated in the seeded (High order Harmonic in Gas seeding) and Echo Enable Harmonic Generation configurations, which performances will be compared. Two pilot user experiments for time-resolved studies of isolated species and magnetization dynamics will take benefit of LUNEX5 FEL radiation.

  17. Case management in France: an economic perspective.

    PubMed

    Frossard, M

    1996-01-01

    Case management is currently an important issue in France. Because neither service providers nor consumers pay for case management in this country, a cost-benefit analysis is often required by the organizations that do pay. Given the context of French social policy and the current focus on justifying case management through cost-benefit analysis, we have developed a way to evaluate its costs. This article presents the limitations of standard economic choice theory, provides a methodology based on the principles of limited rationality, and gives the results of an evaluation of four case management programs. The article provides a method to measure case management costs and efficiency, as well as the willingness of consumers to pay for services.

  18. Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans

    PubMed Central

    Baines, Holly L.; Stewart, James B.; Stamp, Craig; Zupanic, Anze; Kirkwood, Thomas B.L.; Larsson, Nils-Göran; Turnbull, Douglass M.; Greaves, Laura C.

    2014-01-01

    Clonally expanded mitochondrial DNA (mtDNA) mutations resulting in focal respiratory chain deficiency in individual cells are proposed to contribute to the ageing of human tissues that depend on adult stem cells for self-renewal; however, the consequences of these mutations remain unclear. A good animal model is required to investigate this further; but it is unknown whether mechanisms for clonal expansion of mtDNA mutations, and the mutational spectra, are similar between species. Here we show that mice, heterozygous for a mutation disrupting the proof-reading activity of mtDNA polymerase (PolgA+/mut) resulting in an increased mtDNA mutation rate, accumulate clonally expanded mtDNA point mutations in their colonic crypts with age. This results in focal respiratory chain deficiency, and by 81 weeks of age these animals exhibit a similar level and pattern of respiratory chain deficiency to 70-year-old human subjects. Furthermore, like in humans, the mtDNA mutation spectrum appears random and there is an absence of selective constraints. Computer simulations show that a random genetic drift model of mtDNA clonal expansion can accurately model the data from the colonic crypts of wild-type, PolgA+/mut animals, and humans, providing evidence for a similar mechanism for clonal expansion of mtDNA point mutations between these mice and humans. PMID:24915468

  19. Mt. Elgon, Africa, Shaded Relief and Colored Height

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The striking contrast of geologic structures in Africa is shown in this shaded relief image of Mt. Elgon on the left and a section of the Great Rift Valley on the right.

    Mt. Elgon is a solitary extinct volcano straddling the border between Uganda and Kenya, and at 4,321 meters (14,178 feet) tall is the eighth highest mountain in Africa. It is positioned on the Pre-Cambriam bedrock of the Trans Nzoia Plateau, and is similar to other such volcanoes in East Africa in that it is associated with the formation of the Rift Valley. However one thing that sets Mt. Elgon apart is its age.

    Although there is no verifiable evidence of its earliest volcanic activity, Mt. Elgon is estimated to be at least 24 million years old, making it the oldest extinct volcano in East Africa. This presents a striking comparison to Mt. Kilimanjaro, the highest mountain in Africa at 5,895 meters (19,341 feet), which is just over one million years old. Judging by the diameter of its base, it is a common belief among geological experts that Mt. Elgon was once the highest mountains in Africa, however erosion has played a significant role in reducing the height to its present value.

    Juxtaposed with this impressive mountain is a section of the Great Rift Valley, a geological fault system that extends for about 4,830 kilometers (2,995 miles) from Syria to central Mozambique. Erosion has concealed some sections, but in some sections like that shown here, there are sheer cliffs several thousand feet high. The present configuration of the valley, which dates from the mid-Pleistocene epoch, results from a rifting process associated with thermal currents in the Earth's mantle.

    Two visualization methods were combined to produce the image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the northwest-southeast direction, so that northwest slopes appear bright and southeast slopes appear dark. Color coding is directly

  20. Modeling sulfur dioxide concentrations in Mt. Rainier area during prevent

    NASA Astrophysics Data System (ADS)

    Givati, Reuven; Flocchini, Robert G.; Cahill, Thomas A.

    The MATHEW/ADPIC models (a diagnostic wind model and a particle model) which were developed at Lawrence Livermore National Laboratory, were used to compute SO 2 concentrations in the Mt Rainier area during PREVENT (Pacific Northwest Regional Visibility Experiment Using Natural Tracers, June to September 1990). The modeled concentrations were compared to measured concentrations at two sampling locations (Tahoma Woods and Paradise near Mt Rainier) which are located in a valley. The SO 2 sources considered are located along the Puget Sound (Everett, Seattle and Tacoma area) and south of it. New formulations were included in the models for the oxidation of SO 2 and the interpolation of the wind field. Because of the paucity of the meteorological data near the sampling points, an estimation was made of the wind values in the valley, based on the phenomena of wind channeling, mountain and valley winds, and historical wind observations near Mt Rainier. The models were run for several non-rainy days during the PREVENT period when large SO 2 concentrations were observed, and for other special cases. Out of 14 days for which the emissions of the previous night were taken into account, for 12 days the ratio of the modeled to the measured SO 2 concentrations at Tahoma Woods during the daytime, was in the interval 0.45-2.00, considered a good agreement. However, the agreement at Tahoma Woods during the night, and at Paradise during the day and the night, were not as good. It seems that the wind flow near Tahoma Woods under the stable conditions at night, and near the steep terrain of Paradise, were not modeled correctly, with the limited input of available meteorological observations.

  1. DNA Barcoding the Medusozoa using mtCOI

    NASA Astrophysics Data System (ADS)

    Ortman, Brian D.; Bucklin, Ann; Pagès, Francesc; Youngbluth, Marsh

    2010-12-01

    The Medusozoa are a clade within the Cnidaria comprising the classes Hydrozoa, Scyphozoa, and Cubozoa. Identification of medusozoan species is challenging, even for taxonomic experts, due to their fragile forms and complex, morphologically-distinct life history stages. In this study 231 sequences for a portion of the mitochondrial Cytochrome Oxidase I (mtCOI) gene were obtained from 95 species of Medusozoans including; 84 hydrozoans (61 siphonophores, eight anthomedusae, four leptomedusae, seven trachymedusae, and four narcomedusae), 10 scyphozoans (three coronatae, four semaeostomae, two rhizostomae, and one stauromedusae), and one cubozoan. This region of mtCOI has been used as a DNA barcode (i.e., a molecular character for species recognition and discrimination) for a diverse array of taxa, including some Cnidaria. Kimura 2-parameter (K2P) genetic distances between sequence variants within species ranged from 0 to 0.057 (mean 0.013). Within the 13 genera for which multiple species were available, K2P distance between congeneric species ranged from 0.056 to 0.381. A cluster diagram generated by Neighbor Joining (NJ) using K2P distances reliably clustered all barcodes of the same species with ≥99% bootstrap support, ensuring accurate identification of species. Intra- and inter-specific variation of the mtCOI gene for the Medusozoa are appropriate for this gene to be used as a DNA barcode for species-level identification, but not for phylogenetic analysis or taxonomic classification of unknown sequences at higher taxonomic levels. This study provides a set of molecular tools that can be used to address questions of speciation, biodiversity, life-history, and population boundaries in the Medusozoa.

  2. The Magmatic Structure of Mt. Vesuvius: Isotopic and Thermal Constraints

    NASA Astrophysics Data System (ADS)

    Civetta, L.; D'Antonio, M.; de Lorenzo, S.; Gasparini, P.

    2002-12-01

    Mt. Vesuvius is an active volcano famous for the AD 79 eruption that destroyed Pompeii, Herculaneum and Stabiae. Because of the intense urbanization around and on the volcano, the risk today is very high. Therefore, the knowledge of the structure and behavior of the magmatic system is fundamental both for the interpretation of any change in the dynamics of the volcano and for prediction of eruptions. A review of available and new isotopic data on rocks from Mt. Vesuvius, together with mineralogical and geochemical data and recent geophysical results, allow us to constrain a thermal modeling that describes history and present state of Mt. Vesuvius magmatic system. This system is formed by a "deep", complex magmatic reservoir where mantle-derived magmas arrive, stagnate and differentiate. The reservoir extends discontinuously between 10 and 20 km of depth, is hosted in densely fractured crustal rocks, where magmas and crust can interact, and has been fed more than once since 400 ka. The hypothesis of crustal contamination is favored by the high temperatures reached by crustal rocks as a consequence of repetitive intrusions of magma. From the "deep" reservoir magmas of K-basaltic to K-tephritic to K-phonotephritic composition rise to shallow depths where they stagnate at 3-5 km of depth before plinian eruptions, and through crystallization and mixing processes with the residual portion of the feeding systems, generate isotopically and geochemically layered reservoirs. Alternatively, during "open conduit" conditions deep, volatile-rich magma batches rise from the "deep" reservoir to less than 1 km of depth and mix with the crystal-rich, volatile-poor resident magma, triggering eruptions.

  3. Stratospheric dynamics following the eruption of Mt. Pinatubo

    NASA Astrophysics Data System (ADS)

    Match, Aaron; Abalos, Marta; Sheng, Jianxiong; Stenke, Andrea; Paynter, David; Fueglistaler, Stephan

    2016-04-01

    Large volcanic eruptions at low latitudes such as that of Mt. Pinatubo in June 1991 can lead to massively enhanced stratospheric aerosol loading for up to about two years. The enhanced aerosol loading leads to a global cooling in the troposphere as a result of the larger albedo. In the lower stratosphere, the enhanced aerosol leads to a warming of several Kelvins as a result of enhanced absorbed radiation. It has been argued that the characteristic temperature change from volcanic aerosols in the stratosphere - a warming of the low latitudes relative to the high latitudes - tends to induce a more stable polar vortex, and as such a reduced residual circulation. More recently, however, a number of studies have presented calculations of the residual circulation from meteorological reanalyses that suggest that the residual circulation may have been anomalously strong following the Mt. Pinatubo eruption. Similarly, unexpected ozone anomalies in the Southern Hemisphere stratosphere have been linked to a stronger residual circulation. Here, we will present General Circulation Model results, using models ranging in complexity from a primitive equation model to Chemistry-Climate Models, in combination with reanalysis data that aim to provide a mechanistic understanding of the anomalous stratospheric state following the eruption of Mt. Pinatubo. Of particular interest are the impact on model results of the relatively large differences in heating rate perturbations between different data sets of stratospheric aerosol, and the responses in atmospheric dynamics arising from, on the one hand, the specific sea surface temperature pattern of that period and, on the other hand, the response arising from the stratospheric radiative heating perturbation. Our model results suggest that the adjustment in the stratospheric state in response to the in-situ radiative heating perturbation from the volcanic aerosol is probably insufficient to explain the enhanced residual circulation seen

  4. The effects of a wheat germ rich diet on oxidative mtDNA damage, mtDNA copy number and antioxidant enzyme activities in aging Drosophila.

    PubMed

    Mutlu, Ayse Gul

    2013-03-01

    The free radical theory of aging posits that the accumulation of macromolecular damage induced by toxic reactive oxygen species plays a central role in the aging process. Therefore consumption of dietary antioxidants appears to be of great importance. Wheat germ have strong antioxidant properties. Aim of this study is investigate the effects of a wheat germ rich diet on oxidative mtDNA damage, mtDNA copy number and antioxidant enzyme activities in Drosophila. Current results suggested that dietary wheat germ enhances the activities of antioxidant enzymes in Drosophila. There was no statistically difference in mtDNA damage and mtDNA copy number results of "Wheat Germ" and "Refined White Flour" feed groups. mtDNA damage slightly increased with aging in both groups but these changes were no statistically different.

  5. Climbing Mt. Sharp: Maximizing Curiosity's Science Over Traversable Terrains

    NASA Astrophysics Data System (ADS)

    Fraeman, A. A.; Arvidson, R. E.; Bellutta, P.; Sletten, R. S.; Team, M.

    2013-12-01

    As Curiosity transitions from the plains of Gale Crater to the flanks of Mt. Sharp, the rover will begin to encounter material and terrains that could present greater mobility challenges. These challenges include the presence of significantly steeper slopes and large dunes that have the potential to embed the vehicle. Strategic path planning during this phase of the mission will therefore require carefully selecting a traversable route that is both time-efficient and that will provide access to the most scientifically rewarding targets. We consider possible solutions to this optimization problem by examining multiple orbital data sets in order to locate likely mobility hazards and to select potential science waypoints for future in situ investigation. High resolution HiRISE monochromatic images and digital elevation models show filled craters, rock fields, areas with slopes too steep for the rover to traverse, and other possible mobility obstacles on the northwest flank of Mt. Sharp. Using this context, we review accessibility to scientific targets on Mt. Sharp that have been previously discussed in landing site workshop presentations and peer-reviewed publications. Additionally, we identify new targets using detailed geologic maps combined with oversampled CRISM observations that provide mineralogical information at unprecedented high spatial resolutions (up to 6 m/pixel). For example, the spatially sharpened CRISM spectral data show a localized hematite deposit that is associated with the upper-most stratum of a ridge which is located ~3km from the rover's entry point to Mt. Sharp. This deposit may represent a previously habitable environment and is therefore a high priority target for in situ investigation. In order to study the hematite and also to eventually access the phyllosilicate-bearing trough that is located directly behind the ridge, Curiosity will have to cross this ridge, but the ridge edges are often defined by regions with slopes that are too steep

  6. Spine growth mechanisms: friction and seismicity at Mt. Unzen, Japan

    NASA Astrophysics Data System (ADS)

    Hornby, Adrian; Kendrick, Jackie; Hirose, Takehiro; Henton De Angelis, Sarah; De Angelis, Silvio; Umakoshi, Kodo; Miwa, Takahiro; Wadsworth, Fabian; Dingwell, Don; Lavallee, Yan

    2014-05-01

    The final episode of dome growth during the 1991-1995 eruption of Mt. Unzen was characterised by spine extrusion accompanied by repetitive seismicity. This type of cyclic activity has been observed at several dome-building volcanoes and recent work suggests a source mechanism of brittle failure of magma in the conduit. Spine growth may proceed by densification and closure of permeable pathways within the uppermost conduit magma, leading to sealing of the dome and inflation of the edifice. Amplified stresses on the wall rock and plug cause brittle failure near the conduit wall once static friction forces are overcome, and during spine growth these fractures may propagate to the dome surface. The preservation of these features is rare, and the conduit is typically inaccessible; therefore spines, the extruded manifestation of upper conduit material, provide the opportunity to study direct evidence of brittle processes in the conduit. At Mt. Unzen the spine retains evidence for brittle deformation and slip, however mechanical constraints on the formation of these features and their potential impact on eruption dynamics have not been well constrained. Here, we conduct an investigation into the process of episodic spine growth using high velocity friction apparatus at variable shear slip rate (0.4-1.5 m.s-1) and normal stress (0.4-3.5 MPa) on dome rock from Mt. Unzen, generating frictional melt at velocity >0.4 m.s-1 and normal stress >0.7 MPa. Our results show that the presence of frictional melt causes a deviation from Byerlee's frictional rule for rock friction. Melt generation is a disequilibrium process: initial amphibole breakdown leads to melt formation, followed by chemical homogenization of the melt layer. Ultimately, the experimentally generated frictional melts have a similar final chemistry, thickness and comminuted clast size distribution, thereby facilitating the extrapolation of a single viscoelastic model to describe melt-lubricated slip events at Mt

  7. Plutonium Immobilization Can Loading Conceptual Design for 13 MT Case

    SciTech Connect

    Peterson, K.D.

    2001-01-31

    The Plutonium Immobilization Plant (PIP) will encapsulate plutonium in ceramic pucks and seal the pucks inside welded cans. Remote equipment will place these cans in magazines and the magazines in a Defense Waste Processing Facility (DWPF) canister. The DWPF will fill the canister with glass for permanent storage. This report discusses the Plutonium Immobilization Can Loading conceptual design for the 13 Metric Ton (MT) PIP throughput case. This report includes a process block diagram, process description, and preliminary equipment specifications and documents the changes to the original can loading concept documented in previous reports.

  8. Seismic evidence of an extended magmatic sill under Mt. Vesuvius.

    PubMed

    Auger, E; Gasparini, P; Virieux, J; Zollo, A

    2001-11-16

    Mt. Vesuvius is a small volcano associated with an elevated risk. Seismic data were used to better define its magmatic system. We found evidence of an extended (at least 400 square kilometers) low-velocity layer at about 8-kilometer depth. The inferred S-wave (approximately 0.6 to 1.0 kilometer per second) and P-wave velocities (approximately 2.0 kilometer per second) as well as other evidence indicate an extended sill with magma interspersed in a solid matrix.

  9. A miniature VGA SWIR camera using MT6415CA ROIC

    NASA Astrophysics Data System (ADS)

    Eminoglu, Selim; Yilmaz, S. Gokhan; Kocak, Serhat

    2014-06-01

    This paper reports the development of a new miniature VGA SWIR camera called NanoCAM-6415, which is developed to demonstrate the key features of the MT6415CA ROIC such as high integration level, low-noise, and low-power in a small volume. The NanoCAM-6415 uses an InGaAs Focal Plane Array (FPA) with a format of 640 × 512 and pixel pitch of 15 μm built using MT6415CA ROIC. MT6415CA is a low-noise CTIA ROIC, which has a system-on-chip architecture, allows generation of all the required timing and biases on-chip in the ROIC without requiring any external components or inputs, thus enabling the development of compact and low-noise SWIR cameras, with reduced size, weight, and power (SWaP). NanoCAM-6415 camera supports snapshot operation using Integrate-Then-Read (ITR) and Integrate-While-Read (IWR) modes. The camera has three gain settings enabled by the ROIC through programmable Full-Well-Capacity (FWC) values of 10.000 e-, 20.000 e-, and 350.000 e- in the very high gain (VHG), high-gain (HG), and low-gain (LG) modes, respectively. The camera has an input referred noise level of 10 e- rms in the VHG mode at 1 ms integration time, suitable for low-noise SWIR imaging applications. In order to reduce the size and power of the camera, only 2 outputs out of 8 of the ROIC are connected to the external Analog-to-Digital Converters (ADCs) in the camera electronics, providing a maximum frame rate of 50 fps through a 26-pin SDR type Camera Link connector. NanoCAM-6415 SWIR camera without the optics measures 32 mm × 32 mm × 35 mm, weighs 45gr, and dissipates less than 1.8 W using a 5 V supply. These results show that MT6415CA ROIC can successfully be used to develop cameras for SWIR imaging applications where SWaP is a concern. Mikro-Tasarim has also developed new imaging software to demonstrate the functionality of this miniature VGA camera. Mikro-Tasarim provides tested ROIC wafers and also offers compact and easy-to-use test electronics, demo cameras, and hardware

  10. Partial reanimation of experimental complex ANI at Mt. Aragats (proposal)

    NASA Astrophysics Data System (ADS)

    Shaulov, S.B.; Martirosov, R.M.; Mamidjanian, E.A.; Jones, L.W.; Saavedra, O.; Tamada, M.

    We present the proposal for reanimation of the half-built experimental complex ANI at Mt. Aragats (Armenia, 3200 m a.s.l.). It is proposed as a first stage to complete the functioning GAMMA installation by big X-ray emulsion chamber for detailed study of EAS cores at energies 1-100 PeV. Preliminary data obtained in this fieled by the Tien Shan “Hadron” installation are presented. This proposal is an EFT and requests creation of an international cooperation.

  11. Partial reanimation of experimental complex ANI at Mt. Aragats (proposal)

    NASA Astrophysics Data System (ADS)

    Shaulov, S. B.; Martirosov, R. M.; Mamidjanian, E. A.; Jones, L. W.; Saavedra, O.; Tamada, M.

    2009-12-01

    The proposal is presented for reanimation of the half-built experimental complex ANI at Mt. Aragats (Armenia, 3200 m a.s.l.). It is proposed as a first stage to complete the functioning GAMMA installation by big X-ray emulsion chamber for detailed study of extensive air shower cores at energies 1-100 PeV. Preliminary data obtained in this field by the Tien-Shan HADRON installation are presented. This proposal is an EFT and requests creation of an international cooperation.

  12. A VIEW TO THE SOUTHWEST TOWARD MT. SAN ANTONIO FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    A VIEW TO THE SOUTHWEST TOWARD MT. SAN ANTONIO FROM THE UNION PACIFIC RAILROAD TRACK NEAR CAJON PASS. VISIBLE FROM LEFT TO RIGHT ARE THE SANDSTONE OUTCROPS AT SULLIVAN’S CURVE IN THE FAR LEFT DISTANCE; BNSF RAILROAD MAIN TRACK 2 CURVING THROUGH THE HILLS IN THE LEFT DISTANCE; HILL 58.2 AT CENTER, MARKED BY AN ISOLATED STAND OF TREES; BNSF RAILROAD MAIN TRACK 1, RUNNING STRAIGHT THROUGH THE CENTER OF THE PHOTOGRAPH; AND THE UNION PACIFIC TRACK AT THE FAR RIGHT. 123 - Burlington Northern Santa Fe Railroad, Cajon Subdivision, Between Cajon Summit and Keenbrook, Devore, San Bernardino County, CA

  13. Atomic Mass and Nuclear Binding Energy for Mt-283 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-283 (Meitnerium, atomic number Z = 109, mass number A = 283).

  14. Atomic Mass and Nuclear Binding Energy for Mt-324 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-324 (Meitnerium, atomic number Z = 109, mass number A = 324).

  15. Atomic Mass and Nuclear Binding Energy for Mt-295 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-295 (Meitnerium, atomic number Z = 109, mass number A = 295).

  16. Atomic Mass and Nuclear Binding Energy for Mt-280 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-280 (Meitnerium, atomic number Z = 109, mass number A = 280).

  17. Atomic Mass and Nuclear Binding Energy for Mt-320 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-320 (Meitnerium, atomic number Z = 109, mass number A = 320).

  18. Atomic Mass and Nuclear Binding Energy for Mt-284 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-284 (Meitnerium, atomic number Z = 109, mass number A = 284).

  19. Atomic Mass and Nuclear Binding Energy for Mt-300 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-300 (Meitnerium, atomic number Z = 109, mass number A = 300).

  20. Atomic Mass and Nuclear Binding Energy for Mt-336 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-336 (Meitnerium, atomic number Z = 109, mass number A = 336).

  1. Atomic Mass and Nuclear Binding Energy for Mt-319 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-319 (Meitnerium, atomic number Z = 109, mass number A = 319).

  2. Atomic Mass and Nuclear Binding Energy for Mt-290 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-290 (Meitnerium, atomic number Z = 109, mass number A = 290).

  3. Atomic Mass and Nuclear Binding Energy for Mt-328 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-328 (Meitnerium, atomic number Z = 109, mass number A = 328).

  4. Atomic Mass and Nuclear Binding Energy for Mt-273 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-273 (Meitnerium, atomic number Z = 109, mass number A = 273).

  5. Atomic Mass and Nuclear Binding Energy for Mt-307 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-307 (Meitnerium, atomic number Z = 109, mass number A = 307).

  6. Atomic Mass and Nuclear Binding Energy for Mt-329 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-329 (Meitnerium, atomic number Z = 109, mass number A = 329).

  7. Atomic Mass and Nuclear Binding Energy for Mt-352 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-352 (Meitnerium, atomic number Z = 109, mass number A = 352).

  8. Atomic Mass and Nuclear Binding Energy for Mt-316 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-316 (Meitnerium, atomic number Z = 109, mass number A = 316).

  9. Atomic Mass and Nuclear Binding Energy for Mt-267 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-267 (Meitnerium, atomic number Z = 109, mass number A = 267).

  10. Atomic Mass and Nuclear Binding Energy for Mt-294 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-294 (Meitnerium, atomic number Z = 109, mass number A = 294).

  11. Atomic Mass and Nuclear Binding Energy for Mt-332 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-332 (Meitnerium, atomic number Z = 109, mass number A = 332).

  12. Atomic Mass and Nuclear Binding Energy for Mt-271 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-271 (Meitnerium, atomic number Z = 109, mass number A = 271).

  13. Atomic Mass and Nuclear Binding Energy for Mt-297 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-297 (Meitnerium, atomic number Z = 109, mass number A = 297).

  14. Atomic Mass and Nuclear Binding Energy for Mt-312 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-312 (Meitnerium, atomic number Z = 109, mass number A = 312).

  15. Atomic Mass and Nuclear Binding Energy for Mt-321 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-321 (Meitnerium, atomic number Z = 109, mass number A = 321).

  16. Atomic Mass and Nuclear Binding Energy for Mt-274 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-274 (Meitnerium, atomic number Z = 109, mass number A = 274).

  17. Atomic Mass and Nuclear Binding Energy for Mt-358 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-358 (Meitnerium, atomic number Z = 109, mass number A = 358).

  18. Atomic Mass and Nuclear Binding Energy for Mt-296 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-296 (Meitnerium, atomic number Z = 109, mass number A = 296).

  19. Atomic Mass and Nuclear Binding Energy for Mt-277 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-277 (Meitnerium, atomic number Z = 109, mass number A = 277).

  20. Atomic Mass and Nuclear Binding Energy for Mt-301 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-301 (Meitnerium, atomic number Z = 109, mass number A = 301).

  1. Atomic Mass and Nuclear Binding Energy for Mt-342 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-342 (Meitnerium, atomic number Z = 109, mass number A = 342).

  2. Atomic Mass and Nuclear Binding Energy for Mt-302 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-302 (Meitnerium, atomic number Z = 109, mass number A = 302).

  3. Atomic Mass and Nuclear Binding Energy for Mt-268 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-268 (Meitnerium, atomic number Z = 109, mass number A = 268).

  4. Atomic Mass and Nuclear Binding Energy for Mt-272 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-272 (Meitnerium, atomic number Z = 109, mass number A = 272).

  5. Atomic Mass and Nuclear Binding Energy for Mt-349 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-349 (Meitnerium, atomic number Z = 109, mass number A = 349).

  6. Atomic Mass and Nuclear Binding Energy for Mt-270 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-270 (Meitnerium, atomic number Z = 109, mass number A = 270).

  7. Atomic Mass and Nuclear Binding Energy for Mt-322 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-322 (Meitnerium, atomic number Z = 109, mass number A = 322).

  8. Atomic Mass and Nuclear Binding Energy for Mt-299 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-299 (Meitnerium, atomic number Z = 109, mass number A = 299).

  9. Atomic Mass and Nuclear Binding Energy for Mt-278 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-278 (Meitnerium, atomic number Z = 109, mass number A = 278).

  10. Atomic Mass and Nuclear Binding Energy for Mt-343 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-343 (Meitnerium, atomic number Z = 109, mass number A = 343).

  11. Atomic Mass and Nuclear Binding Energy for Mt-298 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-298 (Meitnerium, atomic number Z = 109, mass number A = 298).

  12. Atomic Mass and Nuclear Binding Energy for Mt-313 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-313 (Meitnerium, atomic number Z = 109, mass number A = 313).

  13. Atomic Mass and Nuclear Binding Energy for Mt-339 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-339 (Meitnerium, atomic number Z = 109, mass number A = 339).

  14. Atomic Mass and Nuclear Binding Energy for Mt-287 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-287 (Meitnerium, atomic number Z = 109, mass number A = 287).

  15. Atomic Mass and Nuclear Binding Energy for Mt-304 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-304 (Meitnerium, atomic number Z = 109, mass number A = 304).

  16. Atomic Mass and Nuclear Binding Energy for Mt-282 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-282 (Meitnerium, atomic number Z = 109, mass number A = 282).

  17. Atomic Mass and Nuclear Binding Energy for Mt-327 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-327 (Meitnerium, atomic number Z = 109, mass number A = 327).

  18. Atomic Mass and Nuclear Binding Energy for Mt-276 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-276 (Meitnerium, atomic number Z = 109, mass number A = 276).

  19. Atomic Mass and Nuclear Binding Energy for Mt-350 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-350 (Meitnerium, atomic number Z = 109, mass number A = 350).

  20. Atomic Mass and Nuclear Binding Energy for Mt-317 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-317 (Meitnerium, atomic number Z = 109, mass number A = 317).

  1. Atomic Mass and Nuclear Binding Energy for Mt-326 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-326 (Meitnerium, atomic number Z = 109, mass number A = 326).

  2. Atomic Mass and Nuclear Binding Energy for Mt-354 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-354 (Meitnerium, atomic number Z = 109, mass number A = 354).

  3. Atomic Mass and Nuclear Binding Energy for Mt-351 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-351 (Meitnerium, atomic number Z = 109, mass number A = 351).

  4. Atomic Mass and Nuclear Binding Energy for Mt-265 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-265 (Meitnerium, atomic number Z = 109, mass number A = 265).

  5. Atomic Mass and Nuclear Binding Energy for Mt-353 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-353 (Meitnerium, atomic number Z = 109, mass number A = 353).

  6. Atomic Mass and Nuclear Binding Energy for Mt-285 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-285 (Meitnerium, atomic number Z = 109, mass number A = 285).

  7. Atomic Mass and Nuclear Binding Energy for Mt-341 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-341 (Meitnerium, atomic number Z = 109, mass number A = 341).

  8. Atomic Mass and Nuclear Binding Energy for Mt-359 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-359 (Meitnerium, atomic number Z = 109, mass number A = 359).

  9. Atomic Mass and Nuclear Binding Energy for Mt-335 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-335 (Meitnerium, atomic number Z = 109, mass number A = 335).

  10. Atomic Mass and Nuclear Binding Energy for Mt-338 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-338 (Meitnerium, atomic number Z = 109, mass number A = 338).

  11. Atomic Mass and Nuclear Binding Energy for Mt-264 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-264 (Meitnerium, atomic number Z = 109, mass number A = 264).

  12. Atomic Mass and Nuclear Binding Energy for Mt-347 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-347 (Meitnerium, atomic number Z = 109, mass number A = 347).

  13. Atomic Mass and Nuclear Binding Energy for Mt-337 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-337 (Meitnerium, atomic number Z = 109, mass number A = 337).

  14. Atomic Mass and Nuclear Binding Energy for Mt-344 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-344 (Meitnerium, atomic number Z = 109, mass number A = 344).

  15. Atomic Mass and Nuclear Binding Energy for Mt-340 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-340 (Meitnerium, atomic number Z = 109, mass number A = 340).

  16. Atomic Mass and Nuclear Binding Energy for Mt-318 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-318 (Meitnerium, atomic number Z = 109, mass number A = 318).

  17. Atomic Mass and Nuclear Binding Energy for Mt-315 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-315 (Meitnerium, atomic number Z = 109, mass number A = 315).

  18. Atomic Mass and Nuclear Binding Energy for Mt-308 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-308 (Meitnerium, atomic number Z = 109, mass number A = 308).

  19. Atomic Mass and Nuclear Binding Energy for Mt-310 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-310 (Meitnerium, atomic number Z = 109, mass number A = 310).

  20. Atomic Mass and Nuclear Binding Energy for Mt-311 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-311 (Meitnerium, atomic number Z = 109, mass number A = 311).

  1. Atomic Mass and Nuclear Binding Energy for Mt-309 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-309 (Meitnerium, atomic number Z = 109, mass number A = 309).

  2. Atomic Mass and Nuclear Binding Energy for Mt-289 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-289 (Meitnerium, atomic number Z = 109, mass number A = 289).

  3. Atomic Mass and Nuclear Binding Energy for Mt-305 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-305 (Meitnerium, atomic number Z = 109, mass number A = 305).

  4. Atomic Mass and Nuclear Binding Energy for Mt-331 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-331 (Meitnerium, atomic number Z = 109, mass number A = 331).

  5. Atomic Mass and Nuclear Binding Energy for Mt-288 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-288 (Meitnerium, atomic number Z = 109, mass number A = 288).

  6. Atomic Mass and Nuclear Binding Energy for Mt-357 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-357 (Meitnerium, atomic number Z = 109, mass number A = 357).

  7. Atomic Mass and Nuclear Binding Energy for Mt-330 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-330 (Meitnerium, atomic number Z = 109, mass number A = 330).

  8. Atomic Mass and Nuclear Binding Energy for Mt-303 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-303 (Meitnerium, atomic number Z = 109, mass number A = 303).

  9. Atomic Mass and Nuclear Binding Energy for Mt-306 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-306 (Meitnerium, atomic number Z = 109, mass number A = 306).

  10. Atomic Mass and Nuclear Binding Energy for Mt-281 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-281 (Meitnerium, atomic number Z = 109, mass number A = 281).

  11. Atomic Mass and Nuclear Binding Energy for Mt-286 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-286 (Meitnerium, atomic number Z = 109, mass number A = 286).

  12. Atomic Mass and Nuclear Binding Energy for Mt-291 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-291 (Meitnerium, atomic number Z = 109, mass number A = 291).

  13. Atomic Mass and Nuclear Binding Energy for Mt-348 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-348 (Meitnerium, atomic number Z = 109, mass number A = 348).

  14. Atomic Mass and Nuclear Binding Energy for Mt-275 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-275 (Meitnerium, atomic number Z = 109, mass number A = 275).

  15. Atomic Mass and Nuclear Binding Energy for Mt-323 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-323 (Meitnerium, atomic number Z = 109, mass number A = 323).

  16. Atomic Mass and Nuclear Binding Energy for Mt-355 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-355 (Meitnerium, atomic number Z = 109, mass number A = 355).

  17. Atomic Mass and Nuclear Binding Energy for Mt-346 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-346 (Meitnerium, atomic number Z = 109, mass number A = 346).

  18. Atomic Mass and Nuclear Binding Energy for Mt-345 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-345 (Meitnerium, atomic number Z = 109, mass number A = 345).

  19. Atomic Mass and Nuclear Binding Energy for Mt-293 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-293 (Meitnerium, atomic number Z = 109, mass number A = 293).

  20. Atomic Mass and Nuclear Binding Energy for Mt-325 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-325 (Meitnerium, atomic number Z = 109, mass number A = 325).

  1. Atomic Mass and Nuclear Binding Energy for Mt-356 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-356 (Meitnerium, atomic number Z = 109, mass number A = 356).

  2. Atomic Mass and Nuclear Binding Energy for Mt-314 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-314 (Meitnerium, atomic number Z = 109, mass number A = 314).

  3. Atomic Mass and Nuclear Binding Energy for Mt-333 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-333 (Meitnerium, atomic number Z = 109, mass number A = 333).

  4. Atomic Mass and Nuclear Binding Energy for Mt-269 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-269 (Meitnerium, atomic number Z = 109, mass number A = 269).

  5. Atomic Mass and Nuclear Binding Energy for Mt-266 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-266 (Meitnerium, atomic number Z = 109, mass number A = 266).

  6. Atomic Mass and Nuclear Binding Energy for Mt-279 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-279 (Meitnerium, atomic number Z = 109, mass number A = 279).

  7. Atomic Mass and Nuclear Binding Energy for Mt-292 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-292 (Meitnerium, atomic number Z = 109, mass number A = 292).

  8. Atomic Mass and Nuclear Binding Energy for Mt-334 (Meitnerium)

    NASA Astrophysics Data System (ADS)

    Sukhoruchkin, S. I.; Soroko, Z. N.

    This document is part of the Supplement containing the complete sets of data of Subvolume B `Nuclei with Z = 55 - 100' of Volume 22 `Nuclear Binding Energies and Atomic Masses' of Landolt-Börnstein - Group I `Elementary Particles, Nuclei and Atoms', and additionally including data for nuclei with Z = 101 - 130. It provides atomic mass, mass excess, nuclear binding energy, nucleon separation energies, Q-values, and nucleon residual interaction parameters for atomic nuclei of the isotope Mt-334 (Meitnerium, atomic number Z = 109, mass number A = 334).

  9. Infrared site testing of Mt. Lemmon and Catalina Observatory

    NASA Technical Reports Server (NTRS)

    Kuiper, G. P.

    1973-01-01

    The operation and problems involved with two sky noise meters installed in the Catalina Mountains near Tucson, Arizona are discussed. The instruments were installed at two different locations on Mt. Lemon. It was found that when photometric conditions prevailed, a positive correlation existed between the outputs of the two instruments. In particular, the strongdiurnal effect, in which the sky noise increases abruptly at sunrise and falls markedly after sunset, was reproduced by both instruments. Discrepancies in data recorded by the two instruments are analyzed and possible causes for the discrepancies are proposed.

  10. Effects of Grapevine Leafroll associated Virus 3 (GLRaV-3) and duration of infection on fruit composition and wine chemical profile of Vitis vinifera L. cv. Sauvignon blanc.

    PubMed

    Montero, R; Mundy, D; Albright, A; Grose, C; Trought, M C T; Cohen, D; Chooi, K M; MacDiarmid, R; Flexas, J; Bota, J

    2016-04-15

    In order to determine the effects of Grapevine Leafroll associated Virus 3 (GLRaV-3) on fruit composition and chemical profile of juice and wine from Vitis vinifera L. cv. Sauvignon blanc grown in New Zealand, composition variables were measured on fruit from vines either infected with GLRaV-3 (established or recent infections) or uninfected vines. Physiological ripeness (20.4°Brix) was the criterion established to determine the harvest date for each of the three treatments. Date of grape ripeness was strongly affected by virus infection. In juice and wine, GLRaV-3 infection prior to 2008 reduced titratable acidity compared with the uninfected control. Differences observed in amino acids from the three infection status groups did not modify basic wine chemical properties. In conclusion, GLRaV-3 infection slowed grape ripening, but at equivalent ripeness to result in minimal effects on the juice and wine chemistry. Time of infection produced differences in specific plant physiological variables.

  11. The setting of the Mt. Carmel caves reassessed

    NASA Astrophysics Data System (ADS)

    Vita-Finzi, Claudio; Stringer, Chris

    2007-02-01

    Four caves on the SW flank of Mt. Carmel, es Skhul, el Wad, el Jaml and et Tabun, were first excavated in the 1930s by a team led by Dorothy Garrod. They yielded human remains whose age and evolutionary status remain controversial partly because the complexity of the cave deposits invites conflicting interpretations. The abrasion of artefacts and pebbles in el Wad and es Skhul, which was originally ascribed to spring flow within the caves, is explained here by wave action, with the implication that during part of the Middle Palaeolithic the caves were on the shoreline rather than being separated from it—as they now are—by several kilometres of coastal plain and a height difference of some 45 m. U-series, thermoluminescence (TL) and electron spin resonance (ESR) dating suggests that this occurred about 120,000 years ago, when sea level in the eastern Mediterranean stood 5-6 m above its present position. It follows that Mt. Carmel has subsequently undergone some 40 m of uplift. During the period of maximum submergence, the coastal route between Africa and the northern Mediterranean would have been partly blocked, but the loss of the coastal plain for transit and as a source of animal food was offset by easier access from the caves to marine resources.

  12. Gravity Survey of the Mt. Toondina Impact Structure South Australia

    NASA Technical Reports Server (NTRS)

    Plescia, J. B.; Shoemaker, E. M.; Shoemaker, C. S.

    1994-01-01

    Gravity and seismic reflection data, together with geologic mapping, indicate that the Mt. Toondina feature in South Australia is best interpreted as an eroded 4-km-diameter impact structure consisting of a ring structural depression surrounding a pronounced central uplift. Beds at the center of the structure within the central uplift have been raised as much as 200 m from depth and deformed by convergent flow. Seismic reflection data indicate that deformation extends to depths of only about 800 m; at greater depths the reflectors are nearly flat lying indicating little or no deformation. Gravity data show residual anomalies of +1.0 mGal coincident with the central uplift and a -0.5 mGal low associated with the ring structural depression. Modeling of the gravity data indicates that relatively high-density material occurs within the central uplift, whereas the ring depression is filled with low-density material. The deformation at Mt. Toondina is typical of a complex impact crater; the 4-km diameter is consistent with the expected threshold size for complex craters formed in weak to moderate strength sedimentary rocks.

  13. The novel high-performance 3-D MT inverse solver

    NASA Astrophysics Data System (ADS)

    Kruglyakov, Mikhail; Geraskin, Alexey; Kuvshinov, Alexey

    2016-04-01

    We present novel, robust, scalable, and fast 3-D magnetotelluric (MT) inverse solver. The solver is written in multi-language paradigm to make it as efficient, readable and maintainable as possible. Separation of concerns and single responsibility concepts go through implementation of the solver. As a forward modelling engine a modern scalable solver extrEMe, based on contracting integral equation approach, is used. Iterative gradient-type (quasi-Newton) optimization scheme is invoked to search for (regularized) inverse problem solution, and adjoint source approach is used to calculate efficiently the gradient of the misfit. The inverse solver is able to deal with highly detailed and contrasting models, allows for working (separately or jointly) with any type of MT responses, and supports massive parallelization. Moreover, different parallelization strategies implemented in the code allow optimal usage of available computational resources for a given problem statement. To parameterize an inverse domain the so-called mask parameterization is implemented, which means that one can merge any subset of forward modelling cells in order to account for (usually) irregular distribution of observation sites. We report results of 3-D numerical experiments aimed at analysing the robustness, performance and scalability of the code. In particular, our computational experiments carried out at different platforms ranging from modern laptops to HPC Piz Daint (6th supercomputer in the world) demonstrate practically linear scalability of the code up to thousands of nodes.

  14. Hypocentral Relocations of the 2008 Mt. Carmel, Illinois Aftershock Sequence

    NASA Astrophysics Data System (ADS)

    Shoemaker, K.; Hamburger, M. W.; Pavlis, G. L.; Horton, S. P.; Withers, M. M.

    2009-12-01

    On April 18, 2008, a moderate sized earthquake (Mw 5.2, hypocentral depth of 16 km) occurred near the Indiana-Illinois state border within 3 km of the Mt. Carmel-New Harmony fault at the northern termination of the Wabash Valley Fault System. A total of 257 aftershocks were recorded over the next month by a fourteen-station temporary network deployed by Indiana University and University of Memphis/Center of Earthquake Research and Information (CERI). The number of recorded aftershocks is greater than aftershocks recorded from previous earthquakes in the WVFS of similar magnitude within the last 50 years. The number and density of local stations allowed the generation of precise hypocentral relocations with the combination of waveform cross-correlation and joint hypocentral techniques. The relocated hypocenters indicate a well-defined near-vertical fault plane striking east-west. The fault orientation is consistent with the focal mechanism of the main shock and nearly orthogonal with respect to the trace of the neighboring Mt. Carmel-New Harmony fault. The interpreted ruptured fault orientation suggests the aftershock sequence occurred on a transfer structure at the fault termination. The structure may be related to the change in deformation styles suggested by the transition from the northeast-trending WVFS to the northwest-trending La Salle anticlinorium.

  15. Barometric pressures at extreme altitudes on Mt. Everest: physiological significance.

    PubMed

    West, J B; Lahiri, S; Maret, K H; Peters, R M; Pizzo, C J

    1983-05-01

    Barometric pressures were measured on Mt. Everest from altitudes of 5,400 (base camp) to 8,848 m (summit) during the American Medical Research Expedition to Everest. Measurements at 5,400 m were made with a mercury barometer, and above this most of the pressures were obtained with an accurate crystal-sensor barometer. The mean daily pressures were 400.4 +/- 2.7 (SD) Torr (n = 35) at 5,400 m, 351.0 +/- 1.0 Torr (n = 16) at 6,300 m, 283.6 +/- 1.5 Torr (n = 6) at 8,050 m, and 253.0 Torr (n = 1) at 8,848 m. All these pressures are considerably higher than those predicted from the ICAO Standard Atmosphere. The chief reason is that pressures at altitudes between 2 and 16 km are latitude dependent, being higher near the equator because of the large mass of cold air in the stratosphere of that region. Data from weather balloons show that the pressure at the altitude of the summit of Mt. Everest varies considerably with season, being about 11.5 Torr higher in midsummer than in midwinter. Although the mountain has been climbed without supplementary O2, the very low O2 partial pressure at the summit means that it is at the limit of man's tolerance, and even day-by-day variations in barometric pressure apparently affect maximal O2 uptake.

  16. Reservoir characterization of the Mt. Simon Sandstone, Illinois Basin, USA

    USGS Publications Warehouse

    Frailey, S.M.; Damico, J.; Leetaru, H.E.

    2011-01-01

    The integration of open hole well log analyses, core analyses and pressure transient analyses was used for reservoir characterization of the Mt. Simon sandstone. Characterization of the injection interval provides the basis for a geologic model to support the baseline MVA model, specify pressure design requirements of surface equipment, develop completion strategies, estimate injection rates, and project the CO2 plume distribution.The Cambrian-age Mt. Simon Sandstone overlies the Precambrian granite basement of the Illinois Basin. The Mt. Simon is relatively thick formation exceeding 800 meters in some areas of the Illinois Basin. In the deeper part of the basin where sequestration is likely to occur at depths exceeding 1000 m, horizontal core permeability ranges from less than 1 ?? 10-12 cm 2 to greater than 1 ?? 10-8 cm2. Well log and core porosity can be up to 30% in the basal Mt. Simon reservoir. For modeling purposes, reservoir characterization includes absolute horizontal and vertical permeability, effective porosity, net and gross thickness, and depth. For horizontal permeability, log porosity was correlated with core. The core porosity-permeability correlation was improved by using grain size as an indication of pore throat size. After numerous attempts to identify an appropriate log signature, the calculated cementation exponent from Archie's porosity and resistivity relationships was used to identify which porosity-permeability correlation to apply and a permeability log was made. Due to the relatively large thickness of the Mt. Simon, vertical permeability is an important attribute to understand the distribution of CO2 when the injection interval is in the lower part of the unit. Only core analyses and specifically designed pressure transient tests can yield vertical permeability. Many reservoir flow models show that 500-800 m from the injection well most of the CO2 migrates upward depending on the magnitude of the vertical permeability and CO2 injection

  17. Periodicities of hail precipitation in France

    NASA Astrophysics Data System (ADS)

    Hermida, Lucía; Sánchez, José Luis; Berthet, Claude; Dessens, Jean; López, Laura; Hierro, Rodrigo; Wu, Xueke; García-Ortega, Eduardo

    2013-04-01

    The wavelet analysis is a powerful tool appropriated for studying multiscale and non-stationary processes that occur in finite spatial and temporal domains. Its development began with Morlet and, since then, the wavelet transform (WT) has had better applications in Geophysics. However, the characterization of hail precipitation is not exempt from difficulty, since it deals with phenomenon on a small scale, with elevated spatial and temporal variation. The extreme variability of the frequency and distribution of hail is attributed, among other things, to the same process of its formation. The conditions that influence hail formation span from air masses climatology to lower-scale factors such as orography, wind fields, concentration of ice nuclei or temperature. This last factor is important both from a point of view of convective activity as well as its influence in the height of the freezing point. Thus, it would be possible to do comparative analysis between time series of temperature and diverse hail variables; or, rather, to try to establish a relationship between periodicities found and phenomenon such as ENSO (El Niño, Southern Oscillation) or NAO (North-Atlantic Oscillation). France is one of the European countries that is most affected by hail precipitation. Previous climatic studies have been done with the objective of characterizing the long-term variability of distinct variables of this hydrometeor that is present in the time series. These measurements are obtained using networks of hailpads distributed in French territory and managed by ANELFA. Berthet et al. (2011) observed the annual hail frequency in France, finding successions of three years with high values followed by three years of low values; this being calculated as the number of hailfalls per year divided by the number of hailpad stations that were in use during said year. In the present paper, a wavelet analysis was carried out with the objective of detecting the possible existence of

  18. Single-cell analysis of intercellular heteroplasmy of mtDNA in Leber hereditary optic neuropathy

    SciTech Connect

    Kobayashi, Y.; Sharpe, H.; Brown, N.

    1994-07-01

    The authors have investigated the distribution of mutant mtDNA molecules in single cells from a patient with Leber hereditary optic neuropathy (LHON). LHON is a maternally inherited disease that is characterized by a sudden-onset bilateral loss of central vision, which typically occurs in early adulthood. More than 50% of all LHON patients carry an mtDNA mutation at nucleotide position 11778. This nucleotide change converts a highly conserved arginine residue to histidine at codon 340 in the NADH-ubiquinone oxidoreductase subunit 4 (ND4) gene of mtDNA. In the present study, the authors used PCR amplification of mtDNA from lymphocytes to investigate mtDNA heteroplasmy at the single-cell level in a LHON patient. They found that most cells were either homoplasmic normal or homoplasmic mutant at nucleotide position 11778. Some (16%) cells contained both mutant and normal mtDNA.

  19. ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.

    PubMed

    Lewis, Samantha C; Uchiyama, Lauren F; Nunnari, Jodi

    2016-07-15

    Mitochondrial DNA (mtDNA) encodes RNAs and proteins critical for cell function. In human cells, hundreds to thousands of mtDNA copies are replicated asynchronously, packaged into protein-DNA nucleoids, and distributed within a dynamic mitochondrial network. The mechanisms that govern how nucleoids are chosen for replication and distribution are not understood. Mitochondrial distribution depends on division, which occurs at endoplasmic reticulum (ER)-mitochondria contact sites. These sites were spatially linked to a subset of nucleoids selectively marked by mtDNA polymerase and engaged in mtDNA synthesis--events that occurred upstream of mitochondrial constriction and division machine assembly. Our data suggest that ER tubules proximal to nucleoids are necessary but not sufficient for mtDNA synthesis. Thus, ER-mitochondria contacts coordinate licensing of mtDNA synthesis with division to distribute newly replicated nucleoids to daughter mitochondria.

  20. Modeling flow and nitrate fate at catchment scale in Brittany (France).

    PubMed

    Conan, Céline; Bouraoui, Fayçal; Turpin, Nadine; de Marsily, Ghislain; Bidoglio, Giovanni

    2003-01-01

    In the intensive pig-farming (Sus scrofa) area of Brittany (western France), many surface and subsurface water resources are contaminated by nitrate (NO3) with concentrations that chronically exceed the European Community 50 mg L(-1) drinking standard. To ensure sustainable water supply, the fate of NO3 must be considered in both surface water and ground water. The fate of N was investigated in a Britain catchment, the Coët-Dan watershed, with an integrated management tool: the hydrological SWAT model coupled with the ground water model MODFLOW, and its companion contaminant and solute transport model MT3DMS. The model was validated with respect to water quantity during a 6-yr period and for the NO3 concentration during a 44-mo period, at two gauging stations in the catchment. The coupled models reproduced accurately the measurements. At the basin outlet, the Nash-Sutcliffe coefficients were 0.88 for monthly flow for the entire period and 0.87 for monthly N load. Alternative scenarios were simulated and showed potential benefits of decreasing manure application from 210 to 170 kg N ha(-1) as required by the European Commission Nitrates Directive.

  1. Distinguishing Features of Atmospheric River Storms Linked to Debris Flow Initiation on Mt. Hood, Oregon and Mt. Rainier, Washington

    NASA Astrophysics Data System (ADS)

    Desrochers, J.; Nolin, A. W.

    2011-12-01

    Strong eastern Pacific storms characterized by tropical-sourced moisture and heat are often referred to as Atmospheric Rivers (ARs) and are associated with the triggering of debris flows in the Cascade Mountain Range, USA primarily in the fall season. These storms typically feature freezing levels above 3000 m and heavy precipitation that can saturate slopes and rapidly melt shallow early season snowpack. In a study of periglacial debris flows on Mt. Hood, Oregon and Mt. Rainier, Washington, this combination of factors is proposed to initiate slope failure and subsequent debris flows. However, not all ARs trigger debris flows and other storms not associated with ARs may also lead to debris flows. The presence of these non-triggering storms has led to the question: what features distinguish the storms that trigger debris flows, and do these conditions differ between ARs and other storms? ACARS soundings are used to develop temporally detailed information about freezing levels and storm structure. Supplemental data from the SNOTEL network and NWS WSR-88D radar sites allow for better delineation of storm features and their impact on the ground. Antecedent snowpack, atmospheric temperature profiles, precipitation, and oragraphic enhancement are examined for storms associated with debris flows and those that failed to trigger events to determine what characteristics best differentiate the storms from one another. Specific features within the triggering storms, such as the presence of temperature inversions, are also examined for links to the elevation and geomorphic character of these periglacial debris flow initiation sites.

  2. Melatonin acts through MT1/MT2 receptors to activate hypothalamic Akt and suppress hepatic gluconeogenesis in rats.

    PubMed

    Faria, Juliana A; Kinote, Andrezza; Ignacio-Souza, Letícia M; de Araújo, Thiago M; Razolli, Daniela S; Doneda, Diego L; Paschoal, Lívia B; Lellis-Santos, Camilo; Bertolini, Gisele L; Velloso, Lício A; Bordin, Silvana; Anhê, Gabriel F

    2013-07-15

    Melatonin can contribute to glucose homeostasis either by decreasing gluconeogenesis or by counteracting insulin resistance in distinct models of obesity. However, the precise mechanism through which melatonin controls glucose homeostasis is not completely understood. Male Wistar rats were administered an intracerebroventricular (icv) injection of melatonin and one of following: an icv injection of a phosphatidylinositol 3-kinase (PI3K) inhibitor, an icv injection of a melatonin receptor (MT) antagonist, or an intraperitoneal (ip) injection of a muscarinic receptor antagonist. Anesthetized rats were subjected to pyruvate tolerance test to estimate in vivo glucose clearance after pyruvate load and in situ liver perfusion to assess hepatic gluconeogenesis. The hypothalamus was removed to determine Akt phosphorylation. Melatonin injections in the central nervous system suppressed hepatic gluconeogenesis and increased hypothalamic Akt phosphorylation. These effects of melatonin were suppressed either by icv injections of PI3K inhibitors and MT antagonists and by ip injection of a muscarinic receptor antagonist. We conclude that melatonin activates hypothalamus-liver communication that may contribute to circadian adjustments of gluconeogenesis. These data further suggest a physiopathological relationship between the circadian disruptions in metabolism and reduced levels of melatonin found in type 2 diabetes patients.

  3. Inter-Rater Agreement Measures and the Refinement of Metrics in the PLATO MT Evaluation Paradigm

    DTIC Science & Technology

    2005-07-01

    automated downstream processes are able to perform on MT output. 7 Acknowledgements We acknowledge and thank Lacey Sculley , who spent many long hours...Validation of MT Evaluation Metrics Across Languages. Proceedings of Language Resources and Evaluation Conference, Spain. White, John S. and K...Taylor. (1998). Task- Oriented Metric for MT Evaluation Proceedings of AMTA 1998, Langhorne, PA. White, John S., Jennifer B. Doyon, and Susan W. Talbott

  4. Mitochondrial topoisomerase I (Top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

    PubMed Central

    Khiati, Salim; Dalla Rosa, Ilaria; Sourbier, Carole; Ma, Xuefei; Rao, V. Ashutosh; Neckers, Leonard M; Zhang, Hongliang; Pommier, Yves

    2014-01-01

    Purpose Doxorubicin (DOX) is one of the most effective chemotherapeutic agents. However, up to 30% of the patients treated with DOX suffer from congestive heart failure. The mechanism of DOX cardiotoxicity is likely multifactorial and most importantly, the genetic factors predisposing to DOX cardiotoxicity are unknown. Based on the fact that mtDNA lesions and mitochondrial dysfunctions have been found in human hearts exposed to DOX and that mitochondrial topoisomerase 1 (Top1mt) specifically controls mtDNA homeostasis, we hypothesized that Top1mt knockout (KO) mice might exhibit hypersensitivity to DOX. Experimental Design Wild type (WT) and knockout Top1mt mice were treated once a week with 4 mg/kg DOX for 8 weeks. Heart tissues were analyzed one week after the last treatment. Results Genetic inactivation of Top1mt in mice accentuates mtDNA copy number loss and mtDNA damage in heart tissue following DOX treatment. Top1mt knockout mice also fail to maintain respiratory chain protein production and mitochondrial cristae ultrastructure organization. These mitochondrial defects result in decreased O2 consumption, increased ROS production and enhanced heart muscle damage in animals treated with DOX. Accordingly, Top1mt knockout mice die within 45 days after the last DOX injection under conditions whereas the wild type mice survive. Conclusions Our results provide evidence that mitochondrial topoisomerase I, Top1mt, which is conserved across vertebrates, is critical for cardiac tolerance to DOX and adaptive response to DOX cardiotoxicity. They also suggest the potential of Top1mt single nucleotide polymorphisms (SNP) testing to investigate patient susceptibility to DOX induced cardiotoxicity. PMID:24714774

  5. Metabolic rescue in pluripotent cells from patients with mtDNA disease.

    PubMed

    Ma, Hong; Folmes, Clifford D L; Wu, Jun; Morey, Robert; Mora-Castilla, Sergio; Ocampo, Alejandro; Ma, Li; Poulton, Joanna; Wang, Xinjian; Ahmed, Riffat; Kang, Eunju; Lee, Yeonmi; Hayama, Tomonari; Li, Ying; Van Dyken, Crystal; Gutierrez, Nuria Marti; Tippner-Hedges, Rebecca; Koski, Amy; Mitalipov, Nargiz; Amato, Paula; Wolf, Don P; Huang, Taosheng; Terzic, Andre; Laurent, Louise C; Izpisua Belmonte, Juan Carlos; Mitalipov, Shoukhrat

    2015-08-13

    Mitochondria have a major role in energy production via oxidative phosphorylation, which is dependent on the expression of critical genes encoded by mitochondrial (mt)DNA. Mutations in mtDNA can cause fatal or severely debilitating disorders with limited treatment options. Clinical manifestations vary based on mutation type and heteroplasmy (that is, the relative levels of mutant and wild-type mtDNA within each cell). Here we generated genetically corrected pluripotent stem cells (PSCs) from patients with mtDNA disease. Multiple induced pluripotent stem (iPS) cell lines were derived from patients with common heteroplasmic mutations including 3243A>G, causing mitochondrial encephalomyopathy and stroke-like episodes (MELAS), and 8993T>G and 13513G>A, implicated in Leigh syndrome. Isogenic MELAS and Leigh syndrome iPS cell lines were generated containing exclusively wild-type or mutant mtDNA through spontaneous segregation of heteroplasmic mtDNA in proliferating fibroblasts. Furthermore, somatic cell nuclear transfer (SCNT) enabled replacement of mutant mtDNA from homoplasmic 8993T>G fibroblasts to generate corrected Leigh-NT1 PSCs. Although Leigh-NT1 PSCs contained donor oocyte wild-type mtDNA (human haplotype D4a) that differed from Leigh syndrome patient haplotype (F1a) at a total of 47 nucleotide sites, Leigh-NT1 cells displayed transcriptomic profiles similar to those in embryo-derived PSCs carrying wild-type mtDNA, indicative of normal nuclear-to-mitochondrial interactions. Moreover, genetically rescued patient PSCs displayed normal metabolic function compared to impaired oxygen consumption and ATP production observed in mutant cells. We conclude that both reprogramming approaches offer complementary strategies for derivation of PSCs containing exclusively wild-type mtDNA, through spontaneous segregation of heteroplasmic mtDNA in individual iPS cell lines or mitochondrial replacement by SCNT in homoplasmic mtDNA-based disease.

  6. [Studies on mtDNA of Ustilago maydis. II. Restriction mapping].

    PubMed

    Feng, G H; Cheng, W; Lu, S Y

    1991-01-01

    A restriction map was constructed for mtDNA of Ustilago maydis. The fragment order for each restriction enzyme was determined by DNA hybridization and fragment overlapping. The restriction sites were located by analysing the secondary digestions of the cloned mtDNA fragments. It was also found that the mtDNA of U. maydis was a circle molecule (60.7 kb), without recognizable repeat sequence.

  7. Return on Investment Tool for Effective Medical Training (RITE-MT)

    DTIC Science & Technology

    2016-01-11

    RITE-MT (Return on Investment Tool for Effective Medical Training ) FINAL REPORT Prepared by: Christina Padron, Roberto Champney...SUBTITLE Return on Investment Tool for Effective Medical Training (RITE-MT): 5a. CONTRACT NUMBER N00014-13-C-0277 Phase II Final Report 5b. GRANT...14. ABSTRACT The Return on Investment Tool for Effective Medical Training (RITE-MT) effort sought to develop a decision-support software tool to

  8. [Computerization of hospital blood banks in France].

    PubMed

    Daurat, G; Py, J-Y

    2012-11-01

    In France, most blood products are delivered by the établissement francais du sang, directly to the recipients, and hospital blood banks deliver a minor part, but are independent from it. However that may be, hospital blood banks are hazardous activities regarding to recipients, blood products, blood supply of the hospital and regional blood supply. Because of the high risk level, a computerized information system is compulsory for all hospital blood banks, except for those only devoted to vital emergency transfusion. On the field, the integration of computerization in the different processes is very heterogeneous. So, it has been decided to publish guidelines for computerizing hospital blood banks information systems and production management. They have been built according to risk assessment and are intended to minimize those risks. The principle is that all acquisition and processing of data about recipients or blood products and tracking, must be fully computerized and that the result of all manual processes must be checked by computer before proceeding to the next step. The guidelines list the different processes and, for each of them, the functions the software must play. All together, they form the basic level all hospital blood banks should reach. Optional functions are listed. Moreover, the guidelines are also aimed to be a common tool for regional health authorities who supervise hospital blood banks.

  9. [Computerization of hospital blood banks in France].

    PubMed

    Daurat, G; Py, J-Y

    2011-04-01

    In France, most blood products are delivered by the Établissement français du sang, directly to the recipients, and hospital blood banks deliver a minor part, but are independent from it. However that may be, hospital blood banks are hazardous activities regarding recipients, blood products, blood supply for the hospital and regional blood supply. Because of the high risk level, a computerized information system is compulsory for all hospital blood banks, except for those only devoted to vital emergency transfusion. On the field, integration of computerization in the different processes is very heterogeneous. So it has been decided to publish guidelines for computerizing hospital blood banks information systems and production management. They have been built according to risk assessment and are intended to minimize those risks. The principle is that all acquisition and processing of data about recipients or blood products and tracking, must be fully computerized and that the result of all manual processes must be checked by computer before proceeding to the next step. The guidelines list the different processes and, for each of them, the functions the software must play. All together, they form the basic level all hospital blood banks should reach. Optional functions are listed. Moreover, the guidelines are also aimed at being a common tool for regional health authorities who supervise hospital blood banks.

  10. The Quaternary coversands of southwest France

    NASA Astrophysics Data System (ADS)

    Sitzia, Luca; Bertran, Pascal; Bahain, Jean-Jacques; Bateman, Mark D.; Hernandez, Marion; Garon, Henri; de Lafontaine, Guillaume; Mercier, Norbert; Leroyer, Chantal; Queffelec, Alain; Voinchet, Pierre

    2015-09-01

    Detailed stratigraphic analysis and numerical dating (OSL, IRSL, ESR, 14C) of Pleistocene coversands in southwest France enable the construction of a renewed chronostratigraphic framework for sand deposition. The chronological data obtained from sandsheet units testify to the development of transgressive dunefields since at least the Middle Pleistocene (MIS 10). Three main phases of accumulation occurred during the Last Glacial. The oldest one (64-42 ka) is associated with wet sandsheet facies, histic horizons and zibar-type dune fields, which reflect deposition in a context strongly influenced by the groundwater table. The Late Pleniglacial (24-14 ka) corresponds to the main phase of coversand extension in a drier context. Silty gley horizons suggest, however, local interruptions of sand drifting during GS 2.1. Lateglacial stabilization of the coversands may not have occurred before GI-1c (Allerød), which was typified by the development of cumulic arenosols. These were covered by parabolic dunes during the Younger Dryas. The variations in extent of the emerged continental shelf during the glacial-interglacial cycles may explain the uneven geographical distribution of sand deposition through time. Because of coastline retreat up to 100 km north of 45°N during the LGM lowstand, the coversands were unable to reach the northern part of the basin. Comparison with other European regions highlights stronger affinities of the French record with Portugal than with the Netherlands and Great Britain, probably because of reduced influence of permafrost.

  11. Sexology as a profession in France.

    PubMed

    Giami, Alain; de Colomby, Patrick

    2003-08-01

    A national survey of sexologists was carried out in France in 1998-1999, among the individuals listed in the professional directories and the telephone book as "sexologists." It described the sociodemographic characteristics of sexologists, their initial profession and training in sexology, sex therapy and psychotherapeutic techniques, and how they practice sexology. A total of 959 individuals were identified and surveyed. The response rate was 63%. Two thirds of the sexologists were physicians and 60% were men. French sexologists appeared to be segmented into three subgroups: (1) one-third were general practitioners, trained in sexology and psychotherapeutic approaches, recognized themselves as sexologists, and devoted 40% of their professional activity to sexology. Men were about two thirds of this group; (2) one-third were nonphysicians (including psychologists and other health professionals, such as social workers and nurses), recognized themselves as sex therapists and devoted one third of their time to sexology. Men and women were equally represented in this group; (3) one-third were specialists, with less training in sexology and psychotherapeutic techniques, and did not generally recognize themselves as sexologists. They devoted a lesser part of their time to sexology and had academic and hospital practice. Men comprised more than 75% of this group. This study raised the issue of the diversity of primary professions involved in the field of sexology and showed that sexology is a secondary professional choice for the majority of sexologists.

  12. Tick-borne encephalitis in eastern France.

    PubMed

    Hansmann, Yves; Pierre Gut, Jean; Remy, Veronique; Martinot, Martin; Allard Witz, Marie; Christmann, Daniel

    2006-01-01

    Each y a few cases of TBE infection are described in Alsace, France which lies at the occidental limit of the endemic zone of tick-borne encephalitis (TBE). Hence we carried out a retrospective epidemiological and clinical study of TBE infection in Alsace. Data were collected from serological results sent to the Institut de Virologie (Université Louis Pasteur) in Strasbourg. All samples positive for specific IgM against TBE were retained. The physician in charge of each patient was asked to provide clinical, epidemiological and biological data and with his agreement the medical file was referred to us. Since 1968, 64 cases of TBE infection, occurring between April and November, had been described. In 56% of cases, flu-like symptoms preceded neurological symptoms. Most patients had meningitis (54%) or meningoencephalitis (34%). There was no death due to TBE. Two areas were more highly endemic for the disease: the Guebwiller valley in low mountain country and the Neuhof forest, near Strasbourg in the plain of Alsace. In the last 2 y of the study, a third zone seemed to emerge, in the Munster valley. This epidemiological survey revealed the existence in Alsace of 2 endemic zones of TBE with a third zone possibly emerging in the last few y. The survey must be continued to follow the evolution of the disease.

  13. Identifying barriers to Muslim integration in France

    PubMed Central

    Adida, Claire L.; Laitin, David D.; Valfort, Marie-Anne

    2010-01-01

    Is there a Muslim disadvantage in economic integration for second-generation immigrants to Europe? Previous research has failed to isolate the effect that religion may have on an immigrant family's labor market opportunities because other factors, such as country of origin or race, confound the result. This paper uses a correspondence test in the French labor market to identify and measure this religious effect. The results confirm that in the French labor market, anti-Muslim discrimination exists: a Muslim candidate is 2.5 times less likely to receive a job interview callback than is his or her Christian counterpart. A high-n survey reveals, consistent with expectations from the correspondence test, that second-generation Muslim households in France have lower income compared with matched Christian households. The paper thereby contributes to both substantive debates on the Muslim experience in Europe and methodological debates on how to measure discrimination. Following the National Academy of Sciences’ 2001 recommendations on combining a variety of methodologies and applying them to real-world situations, this research identifies, measures, and infers consequences of discrimination based on religious affiliation, controlling for potentially confounding factors, such as race and country of origin. PMID:21098283

  14. Identifying barriers to Muslim integration in France.

    PubMed

    Adida, Claire L; Laitin, David D; Valfort, Marie-Anne

    2010-12-28

    Is there a Muslim disadvantage in economic integration for second-generation immigrants to Europe? Previous research has failed to isolate the effect that religion may have on an immigrant family's labor market opportunities because other factors, such as country of origin or race, confound the result. This paper uses a correspondence test in the French labor market to identify and measure this religious effect. The results confirm that in the French labor market, anti-Muslim discrimination exists: a Muslim candidate is 2.5 times less likely to receive a job interview callback than is his or her Christian counterpart. A high-n survey reveals, consistent with expectations from the correspondence test, that second-generation Muslim households in France have lower income compared with matched Christian households. The paper thereby contributes to both substantive debates on the Muslim experience in Europe and methodological debates on how to measure discrimination. Following the National Academy of Sciences' 2001 recommendations on combining a variety of methodologies and applying them to real-world situations, this research identifies, measures, and infers consequences of discrimination based on religious affiliation, controlling for potentially confounding factors, such as race and country of origin.

  15. View of Mediterranean coast of France

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A vertical view of the Mediterranean coast of France is seen in this Skylab 3 Earth Resources Experiments Package S190-B (five-inch earth terrain camera) photograph taken from the Skylab space station in Earth orbit. This view includes the port cities of Marseilles (near center) and Toulon (far right). The mouth of the Rhone River is on the left. The irregular L-shaped inland body of water is Etang de Berre and is connected to the sea by a narrow canal. The city of Martiques is on the inland side of the canal. Cloud formations form narrow bands or streets along the coast east of Martiques and over the water. Cultural features such as major highways are indicated by thin white lines. Harbor facilities (wharves) and inner city patterns are distinctive in Marseilles and Toulon. The light tan areas in the regions inland from the major cities represent farming communities. The patterns are well shown in the vicinity of the Rhone River. The geology of the region is complex as illustrated by

  16. Briquet and Briquet's syndrome viewed from France.

    PubMed

    Dongier, M

    1983-10-01

    Briquet's contributions to the description of hysteria have been almost completely forgotten in France. One may wonder how he, as well as contemporary French psychiatrists, would react to the approach to hysteria introduced and officialized by DSM III. In particular, its fragmentation into syndromes without apparent link to each other (psychogenic amnesia, conversion disorders, histrionic personality disorder, etc.) and its psychological causation, unbalanced by the consideration of organic factors in etiology, may raise questions. The correlation of conversion disorders with hysterical personality remains a feature of the WHO classification (ICD 9), as well as a feature of French contemporary texts, although it is no longer viewed as a regular association by American psychiatry. It may be that cultural factors lead, as suggested by Brisset, to a repression of conversion phenomena and of hyperexpressivity of affects replaced by more psychosomatic disorders in many contemporary societies. Finally, one may question whether the choice of the term "Briquet Syndrome" is appropriate, as many of the patients described by him did not have the chronic and malignant course described by Guze: It tends to limit hysteria to one end (the most severe one) of a spectrum of disorders.

  17. 19. Photocopy of photograph (from Frances Rand Smith Collection, California ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photocopy of photograph (from Frances Rand Smith Collection, California Historical Society, 1880) Photographer unknown, April 1940 EXTERIOR VIEW OF REAR OF CHURCH - Mission San Miguel Arcangel, Highway 101, San Miguel, San Luis Obispo County, CA

  18. 20. Photocopy of photograph (From Frances Rand Smith Collection, California ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photocopy of photograph (From Frances Rand Smith Collection, California Historical Society) Photographer unknown, Date unknown VIEW OF CHURCH FROM REAR - Mission San Miguel Arcangel, Highway 101, San Miguel, San Luis Obispo County, CA

  19. 16. Photocopy of photograph (from Frances Rand Smith Collection, California ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of photograph (from Frances Rand Smith Collection, California Historical Society, 1900) Photographer unknown, Date unknown FRONT VIEW OF MISSION, c. 1900 - Mission San Miguel Arcangel, Highway 101, San Miguel, San Luis Obispo County, CA

  20. A short account of forensic dentistry in France.

    PubMed

    Riaud, Xavier

    2016-01-01

    The earliest records and more recent cases where forensic dentistry has been used to identify bodies in France are described. The establishment of the French Society of Forensic Odontology is detailed.

  1. History as Passport: Frances FitzGerald and Her Critics.

    ERIC Educational Resources Information Center

    Westfall, William

    1981-01-01

    Attempts to get at some of the assumptions and definitions behind "America Revised" by Frances FitzGerald and, in addition, to investigate some of the conceptions of history held by critics who reviewed the book. (DB)

  2. African human mtDNA phylogeography at-a-glance.

    PubMed

    Rosa, Alexandra; Brehem, António

    2011-01-01

    The mitochondrial DNA (mtDNA) genetic system has long proven to be useful for studying the demographic history of our species, since their proposed Southeast/East African origin 200 kya. Despite the weak archaeological and anthropologic records, which render a difficult understanding of early intra- continental migrations, the phylogenetic L0-L1'6 split at about 140-160 kya is thought to represent also an early sub-structuring of small and isolated communities in South and East Africa. Regional variation accumulated over the following millennia, with L2 and L3 lineages arising in Central and East Africa 100-75 kya. Their sub-Saharan dispersal not later than 60 kya, largely overwhelmed the L0'1 distribution, nowadays limited to South African Khoisan and Central African Pygmies. Cyclic expansions and retractions of the equatorial forest between 40 kya and the "Last Glacial Aridity Maximum" were able to reduce the genetic diversity of modern humans. Surviving regional-specific lineages have emerged from the Sahelian refuge areas, repopulating the region and contributing to the overall West African genetic similarity. Particular L1- L3 lineages mirror the substantial population growth made possible by moister and warmer conditions of the Sahara's Wet Phase and the adoption of agriculture and iron smelting techniques. The diffusion of the farming expertise from a Central African source towards South Africa was mediated by the Bantu people 3 kya. The strong impact of their gene flow almost erased the pre-existent maternal pool. Non-L mtDNAs testify for Eurasian lineages that have enriched the African maternal pool at different timeframes: i) Near and Middle Eastern influences in Upper Palaeolithic, probably link to the spread of Afro-Asiatic languages; ii) particular lineages from West Eurasia around or after the glacial period; iii) post-glacial mtDNA signatures from the Franco-Cantabrian refugia, that have crossed the Strait of Gibraltar and iv) Eurasian lineages

  3. Oxygen isotope geochemistry of mafic magmas at Mt. Vesuvius

    NASA Astrophysics Data System (ADS)

    Dallai, Luigi; Raffaello, Cioni; Chiara, Boschi; Claudia, D'oriano

    2010-05-01

    Pumice and scoria from different eruptive layers of Mt. Vesuvius volcanic products contain mafic minerals consisting of High-Fo olivine and Diopsidic Pyroxene. These phases were crystallized in unerupted trachibasaltic to tephritic magmas, and were brought to surface by large phonolitic/tephri-phonolitic (e.g. Avellino and Pompei) and/or of tephritic and phono-tephritic (Pollena) eruptions. A large set of these mm-sized crystals was accurately separated from selected juvenile material and measured for their chemical compositions (EPMA, Laser Ablation ICP-MS) and 18O/16O ratios (conventional laser fluorination) to constrain the nature and evolution of the primary magmas at Mt. Vesuvius. Uncontaminated mantle δ18O values are hardly recovered in Italian Quaternary magmas, mostly due to the widespread occurrence of crustal contamination of the primary melts during their ascent to the surface (e.g. Alban Hills, Ernici Mts., and Aeolian Islands). At Mt. Vesuvius, measured olivine and clinopyroxene share quite homogeneous chemical compositions (Olivine Fo 85-90 ; Diopside En 45-48, respectively), and represent phases crystallized in near primary mafic magmas. Trace element composition constrains the near primary nature of the phases. Published data on volatile content of melt inclusions hosted in these crystals reveal the coexistence of dissolved water and carbon dioxide, and a minimum trapping pressure around 200-300 MPa, suggesting that crystal growth occurred in a reservoir at about 8-10 km depth. Recently, experimental data have suggested massive carbonate assimilation (up to about 20%) to derive potassic alkali magmas from trachybasaltic melts. Accordingly, the δ18O variability and the trace element content of the studied minerals suggest possible contamination of primary melts by an O-isotope enriched, REE-poor contaminant like the limestone of Vesuvius basement. Low, nearly primitive δ18O values are observed for olivine from Pompeii eruption, although still

  4. MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features

    PubMed Central

    Li, Xiaoran; Zhong, Yali; Lu, Jie; Axcrona, Karol; Eide, Lars; Syljuåsen, Randi G.; Peng, Qian; Wang, Junbai; Zhang, Hongquan; Goscinski, Mariusz Adam; Kvalheim, Gunnar; Nesland, Jahn M.; Suo, Zhenhe

    2016-01-01

    Reducing mtDNA content was considered as a critical step in the metabolism restructuring for cell stemness restoration and further neoplastic development. However, the connections between mtDNA depletion and metabolism reprograming-based cancer cell stemness in prostate cancers are still lack of studies. Here, we demonstrated that human CRPC cell line PC3 tolerated high concentration of the mtDNA replication inhibitor ethidium bromide (EtBr) and the mtDNA depletion triggered a universal metabolic remodeling process. Failure in completing that process caused lethal consequences. The mtDNA depleted (MtDP) PC3 cells could be steadily maintained in the special medium in slow cycling status. The MtDP PC3 cells contained immature mitochondria and exhibited Warburg effect. Furthermore, the MtDP PC3 cells were resistant to therapeutic treatments and contained greater cancer stem cell-like subpopulations: CD44+, ABCG2+, side-population and ALDHbright. In conclusion, these results highlight the association of mtDNA content, mitochondrial function and cancer cell stemness features. PMID:27248169

  5. REM sleep deprivation promotes a dopaminergic influence in the striatal MT2 anxiolytic-like effects

    PubMed Central

    Noseda, Ana Carolina D.; Targa, Adriano D.S.; Rodrigues, Lais S.; Aurich, Mariana F.; Lima, Marcelo M.S.

    2015-01-01

    The aim of this study was to investigate the possible anxiolytic-like effects of striatal MT2 activation, and its counteraction induced by the selective blockade of this receptor. Furthermore, we analyzed this condition under the paradigm of rapid eye movement (REM) sleep deprivation (REMSD) and the animal model of Parkinson’s disease (PD) induced by rotenone. Male Wistar rats were infused with intranigral rotenone (12 μg/μL), and 7 days later were subjected to 24 h of REMSD. Afterwards the rats underwent striatal micro-infusions of selective melatonin MT2 receptor agonist, 8-M-PDOT (10 μg/μL) or selective melatonin MT2 receptor antagonist, 4-P-PDOT (5 μg/μL) or vehicle. Subsequently, the animals were tested in the open-field (OP) and elevated plus maze (EPM) tests. Results indicated that the activation of MT2 receptors produced anxiolytic-like effects. In opposite, the MT2 blockade did not show an anxiogenic-like effect. Besides, REMSD induced anxiolytic-like effects similar to 8-M-PDOT. MT2 activation generated a prevalent locomotor increase compared to MT2 blockade in the context of REMSD. Together, these results suggest a striatal MT2 modulation associated to the REMSD-induced dopaminergic supersensitivity causing a possible dopaminergic influence in the MT2 anxiolytic-like effects in the intranigral rotenone model of PD. PMID:27226821

  6. 77 FR 43116 - Notice of Inventory Completion: The University of Montana, Missoula, MT; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... were removed from prehistoric archeological site 24MO1071 in Missoula County, MT. Metric analysis and... contact Sally Thompson, University of Montana, Anthropological Curation Facility, Department...

  7. MT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway.

    PubMed

    Bravo-Cordero, Jose J; Marrero-Diaz, Raquel; Megías, Diego; Genís, Laura; García-Grande, Aranzazu; García, Maria A; Arroyo, Alicia G; Montoya, María C

    2007-03-21

    MT1-matrix metalloproteinase (MT1-MMP) is one of the most critical factors in the invasion machinery of tumor cells. Subcellular localization to invasive structures is key for MT1-MMP proinvasive activity. However, the mechanism driving this polarized distribution remains obscure. We now report that polarized exocytosis of MT1-MMP occurs during MDA-MB-231 adenocarcinoma cell migration into collagen type I three-dimensional matrices. Polarized trafficking of MT1-MMP is triggered by beta1 integrin-mediated adhesion to collagen, and is required for protease localization at invasive structures. Localization of MT1-MMP within VSV-G/Rab8-positive vesicles, but not in Rab11/Tf/TfRc-positive compartment in invasive cells, suggests the involvement of the exocytic traffic pathway. Furthermore, constitutively active Rab8 mutants induce MT1-MMP exocytic traffic, collagen degradation and invasion, whereas Rab8- but not Rab11-knockdown inhibited these processes. Altogether, these data reveal a novel pathway of MT1-MMP redistribution to invasive structures, exocytic vesicle trafficking, which is crucial for its role in tumor cell invasiveness. Mechanistically, MT1-MMP delivery to invasive structures, and therefore its proinvasive activity, is regulated by Rab8 GTPase.

  8. No recombination of mtDNA after heteroplasmy for 50 generations in the mouse maternal germline

    PubMed Central

    Hagström, Erik; Freyer, Christoph; Battersby, Brendan J.; Stewart, James B.; Larsson, Nils-Göran

    2014-01-01

    Variants of mitochondrial DNA (mtDNA) are commonly used as markers to track human evolution because of the high sequence divergence and exclusive maternal inheritance. It is assumed that the inheritance is clonal, i.e. that mtDNA is transmitted between generations without germline recombination. In contrast to this assumption, a number of studies have reported the presence of recombinant mtDNA molecules in cell lines and animal tissues, including humans. If germline recombination of mtDNA is frequent, it would strongly impact phylogenetic and population studies by altering estimates of coalescent time and branch lengths in phylogenetic trees. Unfortunately, this whole area is controversial and the experimental approaches have been widely criticized as they often depend on polymerase chain reaction (PCR) amplification of mtDNA and/or involve studies of transformed cell lines. In this study, we used an in vivo mouse model that has had germline heteroplasmy for a defined set of mtDNA mutations for more than 50 generations. To assess recombination, we adapted and validated a method based on cloning of single mtDNA molecules in the λ phage, without prior PCR amplification, followed by subsequent mutation analysis. We screened 2922 mtDNA molecules and found no germline recombination after transmission of mtDNA under genetically and evolutionary relevant conditions in mammals. PMID:24163253

  9. Freeing France: The Allies, the Resistance, and the JEDBURGHs

    DTIC Science & Technology

    2008-01-01

    Lendemains Qui Déchantent: Le Parti Communiste Français À La Libération ([Paris, France]: Presses de la Fondation nationale des sciences politiques ...Province À La Liberation: Les Commissaires De La République, 1943-1946, Travaux Et Recherches De Science Politique ; 32. Paris: Fondation Nationale...des Sciences Politiques , 1975. 180 Kriegsmarine headquarters in Berlin, in actual practice, commanded their air and naval forces in France so not

  10. 77 FR 54353 - Airworthiness Directives; Eurocopter France Helicopters

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... directive (AD) for all Eurocopter France (EC) Model SA-365N, SA-365N1, SA-366G1, AS-365N2, AS 365 N3, EC... to amend 14 CFR part 39 to include an AD that would apply to all Eurocopter France (EC) Model SA-365N, SA-365N1, SA-366G1, AS-365N2, AS 365 N3, EC 155B, and EC155B1 helicopters. That NPRM proposed...

  11. Multiparametric Experiment at Mt. Etna: Investigation on Both Degassing and Eruptive Dynamics

    NASA Astrophysics Data System (ADS)

    Cannata, A.; Privitera, E.

    2014-12-01

    In the framework of the MED-SUV project, a multi-parametric experiment to investigate degassing, explosive and effusive dynamics was performed at Mt. Etna volcano in July 2014. The experiment has involved the so-called "Scientific Team of NEC multi-parametric experiment" composed of researchers/technicians from different institutions in Italy, Germany and France: D. Andronico, T. Barnie, A. Boselli, M. Burton, T. Caltabiano, A. Cannata, D. Carbone, A. Chiarugi, F. Ciancitto, D. Contrafatto, S. Corradini, F. D'Amato, E. Del Bello, F. Donnadieu, F. Ferrari, A. Ferro, S. Gambino, F. Greco, A. Harris, U. Kueppers, A. La Spina, P. Labazuy, G. Leto, L. Lodato, R. Maugeri, L. Merucci, S. Moune, R. Paris, J.J. Pena Fernandez, E. Privitera, M. Queisser, T. Ricci, G. Salerno, R. Z. Sanchez, P. Scarlato, M. Sciotto, S. Scollo, L. Scuderi, J. Sesterhenn, L. Spampinato, L. Spina, J. Taddeucci, X. Wang, L. Zuccarello. The aim was two-fold: first, to study degassing processes at Etna's NE Crater (NEC); second, to investigate the activity at the eruptive fissure (EF) that opened at the base of the NEC in early-July 2014. Indeed, NEC is the main contributor to Etna's gas release, and continuously generates infrasonic events: a result of its impulsive degassing regime. Moreover, the opening of the EF offered a unique opportunity to investigate the partitioning of energy and geophysical signals between degassing, explosive and effusive sources. The field campaign involved coupled deployment of seismometers, microphones, thermopiles, a mini-UV scanner, FTIR spectrometer, SO2 camera systems, high-speed video cameras, thermal and visible cameras, gravimeters, tiltmeters, drones, laser HCl sensor, Lidar and satellite data. Moreover, this experiment gave the opportunity to test the prototype of a DIAL for volcanic CO2 sensing the first time in a volcanic environment. Gathered information were integrated with data simultaneously recorded by the permanent networks run by Istituto Nazionale

  12. Dynamic evolution of the Mt. Cameroon volcanic edifice

    NASA Astrophysics Data System (ADS)

    Barfod, Dan N.; Njome, Manga S.; Suh, Cheo E.; Godfrey Fitton, J.

    2014-05-01

    The growth and destruction of a volcanic edifice reflects dynamic processes that shape the Earth, including transport of mass and heat in a cooling planet versus the mechanical and chemical degradation of igneous material driving toward equilibrium. Central to understanding the nature of volcanoes are determinations of the rates of change in the volumes of these features. Through a quantitative temporal framework it is possible to elucidate the relative importance of competing processes that govern growth and destruction of volcanoes, e.g., magma production versus mass wasting. As the energetics of constructive and destructive processes are directly linked to the hazards that they pose to human populations and because volcanoes are stochastic systems, the only means of long-term forecast is via comprehensive understanding of volcanic history. Mount Cameroon is one of Africa's largest volcanoes and is currently the only active centre on the Cameroon line. The edifice is 4 km high with a volume of at least 1200 km3. Seventeen eruptions have been reported since 1800 and a time-averaged eruption volume of 6 x 106 m3/year is calculated from 7 eruptions over the past 91 years. Eight new Ar/Ar ages have been determined for basaltic rocks distributed across Mt. Cameroon; plateau ages are 4139±19 ka, 195±2 ka, 187±5 ka, 161±2 ka, 82±4, 68±3, 14±4 and 2±4 ka (1σ). The upper age from this set defines the oldest age yet measured for the Mt. Cameroon system. The data demonstrate activity through the mid to upper Pleistocene, continuing through to modern activity. Using recent estimates for basin-wide erosion of ca. 0.05 mm/a on a similar edifice (Kauai, Hawaii, Gayer et al 2008) and extrapolating over the Mt. Cameroon edifice yields an erosion rate of 5x104 m3/a, a factor of 30 times lower than the modern magma production rate. Considering these two fluxes implies that approximately 700 ka is required to construct an edifice of 1200 km3 (the current volume of Mt

  13. The Multi-Stage History of Mt. Sharp

    NASA Astrophysics Data System (ADS)

    Allen, C.; Dapremont, A.

    2013-12-01

    The Curiosity rover is exploring Gale crater and Mt. Sharp, Gale's 5-km high central mound. We are investigating the history of alteration and erosion of Mt. Sharp using orbital imagery, spectroscopy and rover observations. Our results suggest a significant time gap between emplacement of the upper and lower sections of the mound. Crater counts show that the lower mound was formed soon after Gale itself, and that it contains distinct units ranging in altitude from approximately -4,500 to -1,800 m. Spectral data suggest that many units contain phyllosilicates. We found that these clay-bearing rocks occur in distinct layers concentrated below -2,900 m. Parts of the lower mound exhibit a transition from clays to sulfates with increasing altitude. The lower mound shows evidence of flowing water, including canyons and inverted channels. Wind erosion produced km-scale yardangs and scalloped cliffs. Our mapping shows that many yardangs in the lower mound are clay-bearing, with a predominant orientation of around N-S. Curiosity's ground-level images show myriad fine-scale, mainly horizontal layers in the lower mound. The rover has found stream beds and conglomerates, indicating that water once flowed on the crater floor. Drilling near the deepest point in Gale produced abundant clay, providing additional evidence of aqueous alteration. Upper mound units range in altitude from -2,100 m to +500 m, and mantle the lower mound above an angular unconformity. Most upper mound units are composed of layers. The formation age of the upper mound is unknown, since few craters are preserved. Clay-bearing layers are detectable in several locations, mainly at altitudes near -2,000 m. There is no evidence of water flow, but wind erosion has scalloped the surfaces and edges of layers, and fine-scale yardangs are common. Correlations between yardangs and clay spectra are apparent only in the lowermost units of the upper mound. Yardang orientations vary, and include N-S, NW-SE, and NE

  14. The Multi-Stage History of Mt. Sharp

    NASA Technical Reports Server (NTRS)

    Allen, C.; Dapremont, A.

    2013-01-01

    The Curiosity rover is exploring Gale crater and Mt. Sharp, Gale's 5-km high central mound. We are investigating the history of alteration and erosion of Mt. Sharp using orbital imagery, spectroscopy and rover observations. Our results suggest a significant time gap between emplacement of the upper and lower sections of the mound. Crater counts show that the lower mound was formed soon after Gale itself, and that it contains distinct units ranging in altitude from approximately -4,500 to -1,800 m. Spectral data suggest that many units contain phyllosilicates. We found that these clay-bearing rocks occur in distinct layers concentrated below -2,900 m. Parts of the lower mound exhibit a transition from clays to sulfates with increasing altitude. The lower mound shows evidence of flowing water, including canyons and inverted channels. Wind erosion produced km-scale yardangs and scalloped cliffs. Our mapping shows that many yardangs in the lower mound are clay-bearing, with a predominant orientation of around N-S. Curiosity's ground-level images show myriad fine-scale, mainly horizontal layers in the lower mound. The rover has found stream beds and conglomerates, indicating that water once flowed on the crater floor. Drilling near the deepest point in Gale produced abundant clay, providing additional evidence of aqueous alteration. Upper mound units range in altitude from -2,100 m to +500 m, and mantle the lower mound above an angular unconformity. Most upper mound units are composed of layers. The formation age of the upper mound is unknown, since few craters are preserved. Clay-bearing layers are detectable in several locations, mainly at altitudes near -2,000 m. There is no evidence of water flow, but wind erosion has scalloped the surfaces and edges of layers, and fine-scale yardangs are common. Correlations between yardangs and clay spectra are apparent only in the lowermost units of the upper mound. Yardang orientations vary, and include N-S, NW-SE, and NE

  15. Ethnobotany of the Samburu of Mt. Nyiru, South Turkana, Kenya

    PubMed Central

    Bussmann, Rainer W

    2006-01-01

    Traditional plant use is of extremely high importance in many societies, and prevalent in African communities. This knowledge is however dwindling rapidly due to changes towards a more Western lifestyle. The influence of modern tourism cannot be neglected in this context. This paper examines the plant use of the Samburu of the Mt. Nyiru area in Northern Kenya. The Samburu pastoralists of Kenya are still amongst the most traditional communities of the country and have retained most of their knowledge about the use of a large part of the plants in their environment for a wide variety of purposes. The results indicate that the local population has a very high knowledge of the plants in their surroundings, and attributes a purpose to a large percentage of the plants found. 448 plant species were collected, identified and their Samburu names and traditional uses recorded. 199 species were reported as of "no use". The high proportion of 249 plant species however had some traditional use: The highest number (180 species) was used as fodder, followed by 80 species that had medicinal use. Firewood (59 species), construction (42 species), tools (31 species), food (29 species) and ceremonial use (19 species) ranked far behind. Traditionally the Samburu attribute most illnesses to the effect of pollutants that block or inhibit digestion. This can include "polluted" food, contagion through sick people as well as witchcraft. In most cases the treatment of illness involves herbal purgatives to cleanse the patient. There are however frequent indications of plant use for common problems like wounds, parasites, body aches and burns. The change from a nomadic to a more sedentary lifestyle, often observed in other areas of the country, has affected the Samburu of remote Mt. Nyiru to a much lesser extent and did so far not lead to a major loss of traditional plant knowledge. However, overgrazing and over-exploitation of plant resources have already led to a decline of the plant

  16. Remote Observing with Robotic Telescopes on Mt. Hopkins

    NASA Astrophysics Data System (ADS)

    Henry, G. W.

    1994-12-01

    Tennessee State University conducts remote, automatic observing with four robotic telescopes located at the Fairborn Observatory site on Mt. Hopkins, 30 miles south of Tucson. These telescopes run completely unattended; a site control computer monitors the time of day and weather conditions, opens the roof at the beginning of the night, informs each telescope's control computer when observations can begin, and shuts down the site when morning twilight or bad weather intervenes. The Automatic Telescope Instruction Set (ATIS) allows us to program the telescopes and to retrieve data via ASCII file transfers over the Internet. ATIS also includes a set of target selection rules that allow the telescopes to operate autonomously for many weeks or months without our intervention. Over the past several years, Tennessee State University has collaborated with Fairborn to develop precision photometers, software, observing techniques and quality control procedures that have culminated in the automatic acquisition and reduction of high volumes of data with millimagnitude precision. The telescopes are being used for a variety long-term monitoring programs that would be difficult or impossible (and prohibitively expensive) to conduct by traditional manual methods. A 10-inch telescope is dedicated to observations of semi-regular variable stars to uncover their multiple periods. A 16-inch telescope is dedicated to long-term observations of chromospherically active (single and binary) stars to search for activity cycles. Solar-type stars are being monitored by 30-inch and 32-inch telescopes to measure the subtle luminosity variations of these stars associated with their long-term magnetic variations as measured by the HK Project at Mt. Wilson Observatory. An additional project in collaboration with the NASA Ames Research Center seeks to apply artificial intelligence techniques to improve the scheduling of the observations on these telescopes and to develop a software package to

  17. Does Mt Etna creep in a brittle manner?

    NASA Astrophysics Data System (ADS)

    Meredith, P. G.; Heap, M. J.; Baud, P.; Vinciguerra, S.; Bell, A. F.; Main, I. G.

    2010-12-01

    Time-dependent brittle deformation is a fundamental and pervasive process operating in the Earth’s upper crust. Its characterization is a pre-requisite to understanding and unravelling the complexities of crustal evolution and dynamics. The preferential chemical interaction between pore fluids and strained atomic bonds at crack tips, a mechanism known as stress corrosion, allows rock to fail under a constant stress that is well below its short-term strength over an extended period of time; a process known as brittle creep. Here we present the first experimental measurements of brittle creep in a basic rock (basalt from Mt Etna volcano) under triaxial stress conditions. Results from conventional creep experiments demonstrate that creep strain rates are highly and non-linearly dependent on the level of applied stress; with a 20% increase in stress producing close to three orders of magnitude increase in creep strain rate. Results from stress-stepping creep experiments show that creep strain rates are also highly dependent on the effective confining pressure. Stress corrosion reactions are inhibited at higher effective confining pressures, and this is interpreted as being due to a reduction in crack aperture that restricts the transport of reactive species to crack tips. Overall, our results also suggest that a critical level of crack damage is required before the deformation starts to accelerate to failure, regardless of the level of applied stress and the time taken to reach this point. The experimental results are discussed in terms of microstructural observations and fits to a macroscopic creep law, and compared with the observed deformation history at Mt Etna volcano.

  18. Ethnobotany of the Samburu of Mt. Nyiru, South Turkana, Kenya.

    PubMed

    Bussmann, Rainer W

    2006-09-06

    Traditional plant use is of extremely high importance in many societies, and prevalent in African communities. This knowledge is however dwindling rapidly due to changes towards a more Western lifestyle. The influence of modern tourism cannot be neglected in this context. This paper examines the plant use of the Samburu of the Mt. Nyiru area in Northern Kenya. The Samburu pastoralists of Kenya are still amongst the most traditional communities of the country and have retained most of their knowledge about the use of a large part of the plants in their environment for a wide variety of purposes. The results indicate that the local population has a very high knowledge of the plants in their surroundings, and attributes a purpose to a large percentage of the plants found. 448 plant species were collected, identified and their Samburu names and traditional uses recorded. 199 species were reported as of "no use". The high proportion of 249 plant species however had some traditional use: The highest number (180 species) was used as fodder, followed by 80 species that had medicinal use. Firewood (59 species), construction (42 species), tools (31 species), food (29 species) and ceremonial use (19 species) ranked far behind. Traditionally the Samburu attribute most illnesses to the effect of pollutants that block or inhibit digestion. This can include "polluted" food, contagion through sick people as well as witchcraft. In most cases the treatment of illness involves herbal purgatives to cleanse the patient. There are however frequent indications of plant use for common problems like wounds, parasites, body aches and burns. The change from a nomadic to a more sedentary lifestyle, often observed in other areas of the country, has affected the Samburu of remote Mt. Nyiru to a much lesser extent and did so far not lead to a major loss of traditional plant knowledge. However, overgrazing and over-exploitation of plant resources have already led to a decline of the plant

  19. The stress field beneath Mt. Vesuvius (Southern Italy)

    NASA Astrophysics Data System (ADS)

    D'Auria, Luca; Massa, Bruno; De Matteo, Ada

    2014-05-01

    The Somma-Vesuvius is the smallest and one of the youngest volcanoes of the Neapolitan district. Its origin is linked to a Late Pleistocene-Holocene extension occurred along the entire Tyrrhenian margin of the Apennine chain. Nowadays, Mt. Vesuvius is a quiescent strato-volcano. Using different approaches and a comparison between observations and numerical models we have determined the spatial variations in the stress field beneath the volcano edifice. In order to achieve this target we have analyzed a focal mechanism dataset derived from 197 events recorded from Jan. 1999 to Jan. 2012. The main results highlight the presence of two seismogenic volumes characterized by markedly different stress patterns. The two volumes are separated by a layer where the seismic strain release shows a significant decrease. Previous studies postulated the existence, at about the same depth, of a ductile layer allowing the spreading of the Mt. Vesuvius edifice. We interpreted the difference in the stress pattern within the two volumes as the effect of a mechanical decoupling caused by the aforementioned ductile layer. The stress pattern in the top volume is dominated by a reverse faulting style, which agrees with the hypothesis of a seismicity driven by the spreading process. On the other hand, the stress field determined for the deep volume is consistent with a background regional field locally perturbed by the effects of the topography and of heterogeneities in the volcanic structure. Since the seismicity of the deep volume shows an intermittent behaviour and has shown to be linked to geochemical variations in the fumaroles of the volcano, we hypothesize that it results from the effect of fluid injection episodes, possibly of magmatic origin, perturbing the pore pressure within the hydrothermal system. The retrieved changes in the stress pattern could indicate variations in volcano dynamics potentially linked to the intrusion of magma at shallow depth.

  20. Observations of volcanic tremor at Mt. St. Helens volcano

    SciTech Connect

    Fehler, M.

    1982-06-25

    Digital recordings of ground motion during tremor episodes accompanying eruptions at Mt. St. Helens Volcano in the state of Washington on August 7 and October 16-18, 1980 are studied. The spectra of the vertical component waveforms contain at least two dominant peaks at 1.0 and 1.3 Hz for all events recorded during both eruptions that were studied. Spectra of horizontal ground motion show peaks at .9 and 1.1 Hz. the relative amplitudes of the two peaks changes between tremor episodes and during single tremor episodes and show no consistent relation to amplitude of ground motion. Spectra of long period earthquakes are very similar to those of tremor events suggesting that tremor is composed of many long period earthquakes that occur over a period of time. The path effect of tremor waveforms is small since there are no peaks in the spectra of waveforms recorded during tectonic earthquakes occurring in the vicinity of Mt. St. Helens. Amplitudes of ground motion varies between .11 ..mu..m and 4.7 ..mu..m. Seismic moment rates during the two eruptions are calculated using the model of Aki et al. (1977) and found to vary between 6 x 10/sup 18/ and 1 x 10/sup 20/ dynes cm sec/sup -1/ which are larger than values found by Aki et al. (1977) who studied amplitudes of shallow tremor events recorded during the October, 1963 eruption of Kilauea volcano in Hawaii. Study of tremor amplitudes recorded at Corvallis, Oregon leads to the conclusion that tremor accompanying the cataclysmic May 18, 1980 eruption was at least one order of magnitude larger in amplitude than tremor during August and October.

  1. Geographic patterns of mtDNA diversity in Europe.

    PubMed

    Simoni, L; Calafell, F; Pettener, D; Bertranpetit, J; Barbujani, G

    2000-01-01

    Genetic diversity in Europe has been interpreted as a reflection of phenomena occurring during the Paleolithic ( approximately 45,000 years before the present [BP]), Mesolithic ( approximately 18,000 years BP), and Neolithic ( approximately 10,000 years BP) periods. A crucial role of the Neolithic demographic transition is supported by the analysis of most nuclear loci, but the interpretation of mtDNA evidence is controversial. More than 2,600 sequences of the first hypervariable mitochondrial control region were analyzed for geographic patterns in samples from Europe, the Near East, and the Caucasus. Two autocorrelation statistics were used, one based on allele-frequency differences between samples and the other based on both sequence and frequency differences between alleles. In the global analysis, limited geographic patterning was observed, which could largely be attributed to a marked difference between the Saami and all other populations. The distribution of the zones of highest mitochondrial variation (genetic boundaries) confirmed that the Saami are sharply differentiated from an otherwise rather homogeneous set of European samples. However, an area of significant clinal variation was identified around the Mediterranean Sea (and not in the north), even though the differences between northern and southern populations were insignificant. Both a Paleolithic expansion and the Neolithic demic diffusion of farmers could have determined a longitudinal cline of mtDNA diversity. However, additional phenomena must be considered in both models, to account both for the north-south differences and for the greater geographic scope of clinical patterns at nuclear loci. Conversely, two predicted consequences of models of Mesolithic reexpansion from glacial refugia were not observed in the present study.

  2. Pathway of Human AS3MT Arsenic Methylation

    PubMed Central

    2015-01-01

    A synthetic gene encoding human As(III) S-adenosylmethionine (SAM) methyltransferase (hAS3MT) was expressed, and the purified enzyme was characterized. The synthetic enzyme is considerably more active than a cDNA-expressed enzyme using endogenous reductants thioredoxin (Trx), thioredoxin reductase (TR), NADPH, and reduced glutathione (GSH). Each of the seven cysteines (the four conserved residues, Cys32, Cys61, Cys156, and Cys206, and nonconserved, Cys72, Cys85, and Cys250) was individually changed to serine. The nonconserved cysteine derivates were still active. None of the individual C32S, C61S, C156S, and C206S derivates were able to methylate As(III). However, the C32S and C61S enzymes retained the ability to methylate MAs(III). These observations suggest that Cys156 and Cys206 play a different role in catalysis than that of Cys32 and Cys61. A homology model built on the structure of a thermophilic orthologue indicates that Cys156 and Cys206 form the As(III) binding site, whereas Cys32 and Cys61 form a disulfide bond. Two observations shed light on the pathway of methylation. First, binding assays using the fluorescence of a single-tryptophan derivative indicate that As(GS)3 binds to the enzyme much faster than inorganic As(III). Second, the major product of the first round of methylation is MAs(III), not MAs(V), and remains enzyme-bound until it is methylated a second time. We propose a new pathway for hAS3MT catalysis that reconciles the hypothesis of Challenger ((1947) Sci. Prog., 35, 396–416) with the pathway proposed by Hayakawa et al. ((2005) Arch. Toxicol., 79, 183–191). The products are the more toxic and more carcinogenic trivalent methylarsenicals, but arsenic undergoes oxidation and reduction as enzyme-bound intermediates. PMID:25325836

  3. Geographic Patterns of mtDNA Diversity in Europe

    PubMed Central

    Simoni, Lucia; Calafell, Francesc; Pettener, Davide; Bertranpetit, Jaume; Barbujani, Guido

    2000-01-01

    Summary Genetic diversity in Europe has been interpreted as a reflection of phenomena occurring during the Paleolithic (∼45,000 years before the present [BP]), Mesolithic (∼18,000 years BP), and Neolithic (∼10,000 years BP) periods. A crucial role of the Neolithic demographic transition is supported by the analysis of most nuclear loci, but the interpretation of mtDNA evidence is controversial. More than 2,600 sequences of the first hypervariable mitochondrial control region were analyzed for geographic patterns in samples from Europe, the Near East, and the Caucasus. Two autocorrelation statistics were used, one based on allele-frequency differences between samples and the other based on both sequence and frequency differences between alleles. In the global analysis, limited geographic patterning was observed, which could largely be attributed to a marked difference between the Saami and all other populations. The distribution of the zones of highest mitochondrial variation (genetic boundaries) confirmed that the Saami are sharply differentiated from an otherwise rather homogeneous set of European samples. However, an area of significant clinal variation was identified around the Mediterranean Sea (and not in the north), even though the differences between northern and southern populations were insignificant. Both a Paleolithic expansion and the Neolithic demic diffusion of farmers could have determined a longitudinal cline of mtDNA diversity. However, additional phenomena must be considered in both models, to account both for the north-south differences and for the greater geographic scope of clinal patterns at nuclear loci. Conversely, two predicted consequences of models of Mesolithic reexpansion from glacial refugia were not observed in the present study. PMID:10631156

  4. [History of clinical pharmacology in France: adaptation, evaluation, defense and illustration of drug in France 1978-1981].

    PubMed

    Montastruc, Paul

    2014-01-01

    This text illustrates some unknown aspects of the history and beginnings of clinical pharmacology in France in the late 1970s and early 1980s From the current situation, development and objectives of clinical pharmacology are recalled as well as obstacles necessary to overcome to change the paradigm in the field of drug evaluation and appropriate use in France. The text recalls this important moment where French medicine and medical pharmacology entered the modern era.

  5. France, Shaded Relief and Colored Height

    NASA Technical Reports Server (NTRS)

    2003-01-01

    This image of France was generated with data from the Shuttle Radar Topography Mission (SRTM). For this broad view the resolution of the data was reduced to 6 arcseconds (about 185 meters north-south and 127 meters east-west), resampled to a Mercator projection, and the French border outlined. Even at this decreased resolution the variety of landforms comprising the country is readily apparent.

    The upper central part of this scene is dominated by the Paris Basin, which consists of a layered sequence of sedimentary rocks. Fertile soils over much of the area make good agricultural land. The Normandie coast to the upper left is characterized by high, chalk cliffs, while the Brittany coast (the peninsula to the left) is highly indented where deep valleys were drowned by the sea, and the Biscay coast to the southwest is marked by flat, sandy beaches.

    To the south, the Pyrenees form a natural border between France and Spain, and the south-central part of the country is dominated by the ancient Massif Central. Subject to volcanism that has only subsided in the last 10,000 years, these central mountains are separated from the Alps by the north-south trending Rhone River Basin.

    Two visualization methods were combined to produce the image: shading and color coding of topographic height. The shade image was derived by computing topographic slope in the northwest-southeast direction, so that northwest slopes appear bright and southeast slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations.

    Elevation data used in this image were acquired by the Shuttle Radar Topography Mission aboard the Space Shuttle Endeavour, launched on Feb. 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to

  6. History of infrared optronics in France

    NASA Astrophysics Data System (ADS)

    Fouilloy, J. P.; Siriex, Michel B.

    1995-09-01

    In France, the real start of work on the applications of infrared radiations occurred around 1947 - 1948. During many years, technological research was performed in the field of detectors, optical material, modulation techniques, and a lot of measurements were made in order to acquire a better knowledge of the propagation medium and radiation of IR sources, namely those of jet engines. The birth of industrial infrared activities in France started with the Franco-German missile guidance programs: Milan, HOT, Roland and the French air to air missile seeker programs: R530, MAGIC. At these early stages of IR technologies development, it was a great technical adventure for both the governmental agencies and industry to develop: detector technology with PbS and InSb, detector cooling for 3 - 5 micrometer wavelength range, optical material transparent in the infrared, opto mechanical design, signal processing and related electronic technologies. Etablissement Jean Turck and SAT were the pioneers associated with Aerospatiale, Matra and under contracts from the French Ministry of Defence (DGA). In the 60s, the need arose to enhance night vision capability of equipment in service with the French Army. TRT was chosen by DGA to develop the first thermal imagers: LUTHER 1, 2, and 3 with an increasing number of detectors and image frequency rate. This period was also the era in which the SAT detector made rapid advance. After basic work done in the CNRS and with the support of DGA, SAT became the world leader of MCT photovoltaic detector working in the 8 to 12 micron waveband. From 1979, TRT and SAT were given the responsibility for the joint development and production of the first generation French thermal imaging modular system so-called SMT. Now, THOMSON TTD Optronique takes over the opto-electronics activities of TRT. Laser based systems were also studied for military application using YAG type laser and CO2 laser: Laboratoire de Marcousis, CILAS, THOMSON CSF and SAT have

  7. Contraceptive practices and trends in France.

    PubMed

    Toulemon, L; Leridon, H

    1998-01-01

    This study describes current contraceptive practices in France over the past 30 years, by method, among single men and women, for dual method use, for pregnancy or sexually transmitted disease (STD) prevention, and at 1st intercourse. Data were obtained from the 1994 Fertility and Family Survey and previous fertility surveys. In 1994, 69% of women aged 20-49 years used contraceptives. Most women relied on the pill (about 36%), followed by the IUD (16%). 7% of women were sterilized. About 5% used condoms, and 6% used abstinence or withdrawal. 31% reported not using contraceptives, of whom 3% were sterile. 4% were infertile. 4% were pregnant. 4% desired pregnancy, and 11% had no ongoing sexual relationship. 5% were determined to be at risk for unintended pregnancy. About 83% of women reported ever use of the pill, and 58% had ever used condoms. Typical patterns of use during the 1980s include 10 years of pill use followed by IUD use. Contraceptive behavior only differed among single men and women not in a union. Some men and women reported multiple method use, especially pills and condoms. During 1988-94, pill use increased, IUD use decreased, and condom use increased. Condom use was higher among singles, among the well educated, and in large cities. During 1978-94, natural method use and sterilization declined. Women tended to identify condom use with pregnancy prevention. Men tended to include STD/AIDS prevention. Contraceptive use at 1st intercourse increased over time. Even though contraceptive use increased, the number of induced abortions remained constant, suggesting lower use-effectiveness.

  8. Magnitude M w in metropolitan France

    NASA Astrophysics Data System (ADS)

    Cara, Michel; Denieul, Marylin; Sèbe, Olivier; Delouis, Bertrand; Cansi, Yves; Schlupp, Antoine

    2016-12-01

    The recent seismicity catalogue of metropolitan France Sismicité Instrumentale de l'Hexagone (SI-Hex) covers the period 1962-2009. It is the outcome of a multipartner project conducted between 2010 and 2013. In this catalogue, moment magnitudes (M w) are mainly determined from short-period velocimetric records, the same records as those used by the Laboratoire de Détection Géophysique (LDG) for issuing local magnitudes (M L) since 1962. Two distinct procedures are used, whether M L-LDG is larger or smaller than 4. For M L-LDG >4, M w is computed by fitting the coda-wave amplitude on the raw records. Station corrections and regional properties of coda-wave attenuation are taken into account in the computations. For M L-LDG ≤4, M w is converted from M L-LDG through linear regression rules. In the smallest magnitude range M L-LDG <3.1, special attention is paid to the non-unity slope of the relation between the local magnitudes and M w. All M w determined during the SI-Hex project is calibrated according to reference M w of recent events. As for some small events, no M L-LDG has been determined; local magnitudes issued by other French networks or LDG duration magnitude (M D) are first converted into M L-LDG before applying the conversion rules. This paper shows how the different sources of information and the different magnitude ranges are combined in order to determine an unbiased set of M w for the whole 38,027 events of the catalogue.

  9. Metal music and mental health in France.

    PubMed

    Recours, Robin; Aussaguel, François; Trujillo, Nick

    2009-09-01

    Although numerous authors have associated metal music with social problems such as suicide, self-destruction and Satanism, few studies have been undertaken to examine the mental health of fans of heavy metal music. This study attempts to determine if there is a link between mental health and the enjoyment of this type of music in France. The researchers surveyed 333 fans of metal music. Their mental health was evaluated by the Hospital Anxiety and Depression Scale (HADS), a widely used instrument that measures anxiety and depression. The scores of the sample of metal music fans were then compared to the scores that reveal possible, probable, or severe mental disorders. Qualifying variables included age, gender, status, education, motivation and participation in metal music culture. The results indicated that fans of metal music are mainly young adults (median age = 22.67, SD = 5.29) and tend to be male (87.85 percent). As a whole, metal music fans have levels of anxiety and depression that are similar to and lower than levels in the general population. Specifically, <5 percent of metal music fans surveyed showed pathological symptoms. Subjects that scored higher levels of anxiety and depression were those that had literary and/or arts backgrounds rather than scientific backgrounds, that wrote metal music lyrics, that consumed alcohol and that engaged in the body modification practice of scarification. This study suggests that opponents of metal music should re-examine the basis for their criticism. More scholarly research is needed to better understand the effects of metal music on fans and on society.

  10. The spatial distribution of Mustelidae in France.

    PubMed

    Calenge, Clément; Chadoeuf, Joël; Giraud, Christophe; Huet, Sylvie; Julliard, Romain; Monestiez, Pascal; Piffady, Jérémy; Pinaud, David; Ruette, Sandrine

    2015-01-01

    We estimated the spatial distribution of 6 Mustelidae species in France using the data collected by the French national hunting and wildlife agency under the "small carnivorous species logbooks" program. The 1500 national wildlife protection officers working for this agency spend 80% of their working time traveling in the spatial area in which they have authority. During their travels, they occasionally detect dead or living small and medium size carnivorous animals. Between 2002 and 2005, each car operated by this agency was equipped with a logbook in which officers recorded information about the detected animals (species, location, dead or alive, date). Thus, more than 30000 dead or living animals were detected during the study period. Because a large number of detected animals in a region could have been the result of a high sampling pressure there, we modeled the number of detected animals as a function of the sampling effort to allow for unbiased estimation of the species density. For dead animals -- mostly roadkill -- we supposed that the effort in a given region was proportional to the distance traveled by the officers. For living animals, we had no way to measure the sampling effort. We demonstrated that it was possible to use the whole dataset (dead and living animals) to estimate the following: (i) the relative density -- i.e., the density multiplied by an unknown constant -- of each species of interest across the different French agricultural regions, (ii) the sampling effort for living animals for each region, and (iii) the relative detection probability for various species of interest.

  11. The Ocean Boundary Layer beneath Hurricane Frances

    NASA Astrophysics Data System (ADS)

    Dasaro, E. A.; Sanford, T. B.; Terrill, E.; Price, J.

    2006-12-01

    The upper ocean beneath the peak winds of Hurricane Frances (57 m/s) was measured using several varieties of air-deployed floats as part of CBLAST. A multilayer structure was observed as the boundary layer deepened from 20m to 120m in about 12 hours. Bubbles generated by breaking waves create a 10m thick surface layer with a density anomaly, due to the bubbles, of about 1 kg/m3. This acts to lubricate the near surface layer. A turbulent boundary layer extends beneath this to about 40 m depth. This is characterized by large turbulent eddies spanning the boundary layer. A stratified boundary layer grows beneath this reaching 120m depth. This is characterized by a gradient Richardson number of 1/4, which is maintained by strong inertial currents generated by the hurricane, and smaller turbulent eddies driven by the shear instead of the wind and waves. There is little evidence of mixing beneath this layer. Heat budgets reveal the boundary layer to be nearly one dimensional through much of the deepening, with horizontal and vertical heat advection becoming important only after the storm had passed. Turbulent kinetic energy measurements support the idea of reduced surface drag at high wind speeds. The PWP model correctly predicts the degree of mixed layer deepening if the surface drag is reduced at high wind speed. Overall, the greatest uncertainty in understanding the ocean boundary layer at these extreme wind speeds is a characterization of the near- surface processes which govern the air-sea fluxes and surface wave properties.

  12. Stable isotope and Ar/Ar evidence of prolonged multi-scale fluid flow during exhumation of orogenic crust: example from the Mont Blanc and Aar massifs (NW Alps)

    NASA Astrophysics Data System (ADS)

    Rolland, Yann; Rossi, Magali

    2015-04-01

    The spatial and temporal scales and the geometry of fluid pathways in a collisional orogen are investigated using stable isotope analysis (O, C, H) and 40Ar/39Ar dating of vein minerals formed at c. 11-16 Ma in the Mont Blanc and the Aar External Crystalline Massifs. In both massifs 40Ar/39Ar dating of veins adularia provides evidence for progressive crystallization from 16 to 9 Ma, and mainly at 11-12 Ma following veins opening during shear zone activity. The fluid flow duration thus ranges from 4 to 5 Ma in the two massifs. The δ18O values of vein quartz and calcite are similar to those of undeformed crystalline and sedimentary host-rocks, suggesting rock buffering, while carbon isotope ratios of vein calcites fall into three compositional groups. A-type veins have δ13C values that are buffered by the Helvetic metasediments, which suggests that these veins formed in a closed-system from a locally-derived CO2-rich fluid. The fluid in equilibrium with C-type veins has depleted δ13C values similar to mantle-CO2, while the intermediate δ13C values of B-type veins suggest mixing between the A-type and C-type fluids. These results are in agreement with crustal- to lithosphere-scale upward vertical fluid flow along vertical shear zones related to the strike-slip system bounding the Adriatic block since 16-20 Ma, connecting a deep-seated fluid to some downward flow in the sedimentary cover of External Crystalline Massifs.

  13. Climatically-driven rockfalls in high-alpine steep rockwalls: the North side of the Aiguilles de Chamonix (Mont Blanc massif) since the end of the Little Ice Age

    NASA Astrophysics Data System (ADS)

    Ravanel, Ludovic; Deline, Philip

    2010-05-01

    Rockfall is one of the main process that affect rockwalls, with related risks for people and infrastructures. Nevertheless, the process and its relation with the permafrost degradation remain insufficiently understood, partly due to the lack of data. By comparing old, recent and present photos, and using geomorphological field data, we propose an inventory of the main (volume > 500 m3) rockfalls that affected the North face of the Aiguilles de Chamonix since the end of the Little Ice Age (LIA, c. 1860 AD). We documented 42 rockfalls on this emblematic ridge of the Mont-Blanc massif, ranging in volume from 500 m3 to 65,000 m3 (total volume: 390,000 ± 60,000 m3). The affected rockwalls are mostly with N to NW aspect, ranging in elevation from 2615 m to 3500 m a.s.l.. This suggests that the area is likely characterised with permafrost, of which degradation could trigger a part of the surveyed rockfalls. We observe a very good correlation between rockfall frequency and the air temperature: periods of years with the highest temperatures between 1860 and 2009 AD experienced the highest frequency; 70 % of rockfalls occurred during the two last decades, characterized by an accelerated increase of the warming in the Alps. Warm summers in 1947, 1976, 1983, and 2003, experienced the highest rockfall frequency, which was maximal during the 2003 Summer heatwave. Average elevation of rockfall scars is 3130 m a.s.l., suggesting that the lower limit of permafrost was affected, where degradation is active. For the most part, triggering of the surveyed post-LIA rockfalls in the Aiguilles de Chamonix was probably controlled by the current permafrost degradation.

  14. Mitochondrial DNA (mtDNA) biogenesis: visualization and duel incorporation of BrdU and EdU into newly synthesized mtDNA in vitro.

    PubMed

    Lentz, Stephen I; Edwards, James L; Backus, Carey; McLean, Lisa L; Haines, Kristine M; Feldman, Eva L

    2010-02-01

    Mitochondria are key regulators of cellular energy and are the focus of a large number of studies examining the regulation of mitochondrial dynamics and biogenesis in healthy and diseased conditions. One approach to monitoring mitochondrial biogenesis is to measure the rate of mitochondrial DNA (mtDNA) replication. We developed a sensitive technique to visualize newly synthesized mtDNA in individual cells to study mtDNA replication within subcellular compartments of neurons. The technique combines the incorporation of 5-bromo-2-deoxyuridine (BrdU) and/or 5-ethynyl-2'-deoxyuridine (EdU) into mtDNA, together with a tyramide signal amplification protocol. Employing this technique, we visualized and measured mtDNA biogenesis in individual cells. The labeling procedure for EdU allows for more comprehensive results by allowing the comparison of its incorporation with other intracellular markers, because it does not require the harsh acid or enzyme digests necessary to recover the BrdU epitope. In addition, the utilization of both BrdU and EdU permits sequential pulse-chase experiments to follow the intracellular localization of mtDNA replication. The ability to quantify mitochondrial biogenesis provides an essential tool for investigating the alterations in mitochondrial dynamics involved in the pathogenesis of multiple cellular disorders, including neuropathies and neurodegenerative diseases.

  15. Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions

    PubMed Central

    Caporali, Leonardo; Ghelli, Anna Maria; Iommarini, Luisa; Maresca, Alessandra; Valentino, Maria Lucia; La Morgia, Chiara; Liguori, Rocco; Zanna, Claudia; Barboni, Piero; De Nardo, Vera; Martinuzzi, Andrea; Rizzo, Giovanni; Tonon, Caterina; Lodi, Raffaele; Calvaruso, Maria Antonietta; Cappelletti, Martina; Porcelli, Anna Maria; Achilli, Alessandro; Pala, Maria; Torroni, Antonio; Carelli, Valerio

    2013-01-01

    Complex I (CI) deficiency is a frequent cause of mitochondrial disorders and, in most cases, is due to mutations in CI subunit genes encoded by mitochondrial DNA (mtDNA). In this study, we establish the pathogenic role of the heteroplasmic mtDNA m.3890G>A/MT-ND1 (p.R195Q) mutation, which affects an extremely conserved amino acid position in ND1 subunit of CI. This mutation was found in a young-adult male with optic atrophy resembling Leber's hereditary optic neuropathy (LHON) and bilateral brainstem lesions. The only previously reported case with this mutation was a girl with fatal infantile Leigh syndrome with bilateral brainstem lesions. Transfer of the mutant mtDNA in the cybrid cell system resulted in a marked reduction of CI activity and CI-dependent ATP synthesis in the presence of a normally assembled enzyme. These findings establish the pathogenicity of the m.3890G>A/MT-ND1 mutation and remark the link between CI mutations affecting the mtDNA-encoded ND subunits and LHON-like optic atrophy, which may be complicated by bilateral and symmetric lesions affecting the central nervous system. Peculiar to this mutation is the distribution of the brainstem lesions, with sparing of the striatum in both patients. PMID:23246842

  16. Environmental risk mapping of canine leishmaniasis in France

    PubMed Central

    2010-01-01

    Background Canine leishmaniasis (CanL) is a zoonotic disease caused by Leishmania infantum, a Trypanosomatid protozoan transmitted by phlebotomine sandflies. Leishmaniasis is endemic in southern France, but the influences of environmental and climatic factors on its maintenance and emergence remain poorly understood. From a retrospective database, including all the studies reporting prevalence or incidence of CanL in France between 1965 and 2007, we performed a spatial analysis in order to i) map the reported cases in France, and ii) produce an environment-based map of the areas at risk for CanL. We performed a Principal Component Analysis (PCA) followed by a Hierarchical Ascendant Classification (HAC) to assess if the locations of CanL could be grouped according to environmental variables related to climate, forest cover, and human and dog densities. For each group, the potential distribution of CanL in France was mapped using a species niche modelling approach (Maxent model). Results Results revealed the existence of two spatial groups of CanL cases. The first group is located in the Cévennes region (southern Massif Central), at altitudes of 200-1000 m above sea level, characterized by relatively low winter temperatures (1.9°C average), 1042 mm average annual rainfall and much forest cover. The second group is located on the Mediterranean coastal plain, characterized by higher temperatures, lower rainfall and less forest cover. These two groups may correspond to the environments favoured by the two sandfly vectors in France, Phlebotomus ariasi and Phlebotomus perniciosus respectively. Our niche modelling of these two eco-epidemiological patterns was based on environmental variables and led to the first risk map for CanL in France. Conclusion Results show how an ecological approach can help to improve our understanding of the spatial distribution of CanL in France. PMID:20377867

  17. The apoptotic mechanisms of MT-6, a mitotic arrest inducer, in human ovarian cancer cells.

    PubMed

    Chen, Mei-Chuan; Kuo, Yi-Chiu; Hsu, Chia-Ming; Chen, Yi-Lin; Shen, Chien-Chang; Teng, Che-Ming; Pan, Shiow-Lin

    2017-04-07

    Patients with ovarian cancer are typically diagnosed at an advanced stage, resulting in poor prognosis since there are currently no effective early-detection screening tests for women at average-risk for ovarian cancer. Here, we investigated the effects of MT-6, a derivative of moscatilin, in ovarian cancer cells. Our investigation showed that MT-6 inhibited the proliferation and viability of ovarian cancer cells with submicromolar IC50 values. MT-6-treated SKOV3 cells showed significant cell cycle arrest at G2/M phase, followed by an increase in the proportion of cells in a sub-G1 phase. In addition, MT-6 induced a concentration-dependent increase in mitotic markers, mitotic kinases, cell cycle regulators of G2/M transition, and apoptosis-related markers in ovarian cancer cells. MT-6 treatment also induced mitochondrial membrane potential loss, JNK activation, and DR5 expression. Cotreatment of cells with the JNK inhibitor SP600125 considerably attenuated MT-6-induced apoptosis, mitochondria membrane potential loss, DR5 upregulation, and suppression of cell viability. MT-6 also inhibited tumor growth in an SKOV3 xenograft model without significant body weight loss. Together, our findings suggest that MT-6 is a potent anticancer agent with tumor-suppressive activity in vitro and in vivo that could be further investigated for ovarian cancer therapy in the future.

  18. 75 FR 27287 - South Mt. Baker-Snoqualmie Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    .... ACTION: Notice of meeting. SUMMARY: The South Mt. Baker-Snoqualmie (MBS) Resource Advisory Committee (RAC..., recommend grant funding opportunities to the MBS Forest Supervisor. More information will be posted on the Mt. Baker-Snoqualmie National Forest Web site at:...

  19. 78 FR 67299 - Modification of Class E Airspace; Cut Bank, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-12

    ... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Cut Bank, MT AGENCY... airspace at Cut Bank, MT, to accommodate new Area Navigation (RNAV) Global Positioning System (GPS) standard instrument approach procedures at Cut Bank Municipal Airport. This improves the safety...

  20. 78 FR 65556 - Establishment of Class E Airspace; Cut Bank, MT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-01

    ... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Cut Bank, MT AGENCY... airspace at the Cut Bank VHF Omni-Directional Radio Range Tactical Air Navigational Aid (VORTAC) navigation aid, Cut Bank, MT, to facilitate vectoring of Instrument Flight Rules (IFR) aircraft under control...